LOCUS       DAEQAF010000001       167311 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.001, whole genome shotgun sequence.
ACCESSION   DAEQAF010000001 DAEQAF010000000
VERSION     DAEQAF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 167311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 167311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..167311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.001"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            252..1226
                     /locus_tag="KRN00_000001"
     CDS             252..1226
                     /locus_tag="KRN00_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1825901.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(1342..2403)
                     /locus_tag="KRN00_000002"
     CDS             complement(1342..2403)
                     /locus_tag="KRN00_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1825902.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(3015..3866)
                     /locus_tag="KRN00_000003"
     CDS             complement(3015..3866)
                     /locus_tag="KRN00_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1825903.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(3883..4803)
                     /locus_tag="KRN00_000004"
     CDS             complement(3883..4803)
                     /locus_tag="KRN00_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBH1825904.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(4913..5827)
                     /gene="murQ"
                     /locus_tag="KRN00_000005"
     CDS             complement(4913..5827)
                     /gene="murQ"
                     /locus_tag="KRN00_000005"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBH1825905.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(5926..7023)
                     /locus_tag="KRN00_000006"
     CDS             complement(5926..7023)
                     /locus_tag="KRN00_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH1825906.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDIGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLTGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(7256..8602)
                     /locus_tag="KRN00_000007"
     CDS             complement(7256..8602)
                     /locus_tag="KRN00_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1825907.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(8691..8999)
                     /locus_tag="KRN00_000008"
     CDS             complement(8691..8999)
                     /locus_tag="KRN00_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1825908.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFENE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(9261..9659)
                     /locus_tag="KRN00_000009"
     CDS             complement(9261..9659)
                     /locus_tag="KRN00_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1825909.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKEMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(9661..10821)
                     /locus_tag="KRN00_000010"
     CDS             complement(9661..10821)
                     /locus_tag="KRN00_000010"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBH1825910.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILPKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(11252..12271)
                     /locus_tag="KRN00_000011"
     CDS             complement(11252..12271)
                     /locus_tag="KRN00_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1825911.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVDGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSENGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(12265..12945)
                     /locus_tag="KRN00_000012"
     CDS             complement(12265..12945)
                     /locus_tag="KRN00_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1825912.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(13097..15004)
                     /locus_tag="KRN00_000013"
     CDS             complement(13097..15004)
                     /locus_tag="KRN00_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1825913.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NVLQDENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVVIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIVSIIVIGYGYY
                     LSTNIRTGDITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYGERLVSGNNVIELKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNVYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(15005..15757)
                     /locus_tag="KRN00_000014"
     CDS             complement(15005..15757)
                     /locus_tag="KRN00_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1825914.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFISIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(16073..17227)
                     /locus_tag="KRN00_000015"
     CDS             complement(16073..17227)
                     /locus_tag="KRN00_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1825915.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINILLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYCLIVLLNYLQE"
     gene            complement(17230..17697)
                     /locus_tag="KRN00_000016"
     CDS             complement(17230..17697)
                     /locus_tag="KRN00_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1825916.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(17711..18199)
                     /locus_tag="KRN00_000017"
     CDS             complement(17711..18199)
                     /locus_tag="KRN00_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1825917.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIRQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(18213..19544)
                     /locus_tag="KRN00_000018"
     CDS             complement(18213..19544)
                     /locus_tag="KRN00_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1825918.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKNYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(19558..21123)
                     /locus_tag="KRN00_000019"
     CDS             complement(19558..21123)
                     /locus_tag="KRN00_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1825919.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(21293..22078)
                     /locus_tag="KRN00_000020"
     CDS             complement(21293..22078)
                     /locus_tag="KRN00_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1825920.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(22245..23444)
                     /locus_tag="KRN00_000021"
     CDS             complement(22245..23444)
                     /locus_tag="KRN00_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBH1825921.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNDWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYIDTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(23966..25303)
                     /gene="xylA"
                     /locus_tag="KRN00_000022"
     CDS             complement(23966..25303)
                     /gene="xylA"
                     /locus_tag="KRN00_000022"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBH1825922.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNIARINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(25399..26949)
                     /gene="xylB"
                     /locus_tag="KRN00_000023"
     CDS             complement(25399..26949)
                     /gene="xylB"
                     /locus_tag="KRN00_000023"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBH1825923.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            27157..28317
                     /locus_tag="KRN00_000024"
     CDS             27157..28317
                     /locus_tag="KRN00_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH1825924.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(28473..28877)
                     /locus_tag="KRN00_000025"
     CDS             complement(28473..28877)
                     /locus_tag="KRN00_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1825925.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(28898..29380)
                     /locus_tag="KRN00_000026"
     CDS             complement(28898..29380)
                     /locus_tag="KRN00_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1825926.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(29400..30209)
                     /locus_tag="KRN00_000027"
     CDS             complement(29400..30209)
                     /locus_tag="KRN00_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1825927.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(30202..30981)
                     /locus_tag="KRN00_000028"
     CDS             complement(30202..30981)
                     /locus_tag="KRN00_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1825928.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(30981..33059)
                     /locus_tag="KRN00_000029"
     CDS             complement(30981..33059)
                     /locus_tag="KRN00_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBH1825929.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            33369..34238
                     /locus_tag="KRN00_000030"
     CDS             33369..34238
                     /locus_tag="KRN00_000030"
                     /inference="COORDINATES: protein
                     motif:HMM:NF014376.1,HMM:NF024242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1825930.1"
                     /translation="MNTLKHESVNIHDDIGVKLYLSIDNGSFTVKHWHYSLEVILILN
                     GSFNLFIDNERLNLKENDLIILNPKQIHSAICSDGNESIVLQIPYKFLEENIPNINEL
                     RINYKELLTDTDNTNVNKLKNTLNELYKIYSKEPQLYILNSKILLYEFLYILYVNYSI
                     SIDSISYKNTDKYFDRLKIITDYVKENYKEQISLSTASKVVNLTPQYLSRFFKTHMGI
                     TFTSYVNNIRLENMYSDLINTDNNILDIIQNNGFYNYKQFMKLFKKIYNCTPSQKRQQ
                     INKTRKDVVSKYR"
     gene            complement(34340..35704)
                     /locus_tag="KRN00_000031"
     CDS             complement(34340..35704)
                     /locus_tag="KRN00_000031"
                     /inference="COORDINATES: protein motif:HMM:TIGR00792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1825931.1"
                     /translation="MENNMKQPIIASDKLSGKEKVGYATGDLACNLIFSTVGAFLMYF
                     YTDVYGLAPMAVSMIFLVARIWDGLNDPIMGVIVDRTKSKHGKFRPYLLYGALPFTLI
                     AILCFTVPDISPMGKFVYAFVTYIGLGMIYTLVNVPYGALTSAMTQDSTERANLSVVR
                     MFFASVGTLIVTYGVPKLSTILGGENLAKGYQQAMIIYGIAGGLLLLFCFFTTKERYS
                     VVNEDSEKAGFKDIIVLLKNNKPLVILSLIFILMFGIMSIVDAVGIYFFQYVLGREDL
                     IPTYMILGKGAVLVGYAVTPLLLKKFDKKEIIFWFTVVTLSLPIGMMFLGKEHITLIM
                     ILRVIHGIAYSSTGIMWSLVPDTIEYGELKTGKRREGITYSIIGFFFKFGMALGGLVP
                     GVVLSMTGYVANTSQTSQALYGIRSINGIIPVVLTVAMLVLIKMYPLTEEKCREVINE
                     LRSR"
     gene            complement(35784..38138)
                     /gene="yicI"
                     /locus_tag="KRN00_000032"
     CDS             complement(35784..38138)
                     /gene="yicI"
                     /locus_tag="KRN00_000032"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010964400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HBH1825932.1"
                     /translation="MKFSNGMWLNKGNYTVLHPVELYDMCIEEVKLTAYCPFVKVNTR
                     GNTLDGGMLTTEISSPMENIIKVRITHHAGEKEQSYFKLNEKTPDIKIKENNDNYEFI
                     SGRLKAQIGKGENWGIKFYNNDKLLTETSRTGTAYITTDKKEIYMREQLAIGVGELVY
                     GLGERFTPFVKNGQSVDIWNQDGGTASEQSYKNIPFYLTNKGYGVFVNHSENVSFEVG
                     SESVSKVQFSVEGESLEYYIIGGNDLKEVINNYTNLTGKPTLPPAWSFGLWLTTSFCT
                     NYDEETVMGFIDGMLERDIPLETFHFDCFWMKEFEWCNFEWDNRVFPDPEGMLKRIND
                     KGIKVCVWINPYIGQKSPLYKEGAEKGYFVKTGNNKIWQCDRWQAGMALVDFTNPEAC
                     KWYKSHLERLIDMGVDSFKTDFGERIPVQDEFYGMDALKYGIKYYDGSDSKKMHNYYT
                     YLYNKLVFELLVEKLGNEQACVFARSATVGGQNFPVHWGGDCLSNYPSMAESLRGGLS
                     LSLCGFGYWSHDIGGFEEGCTADIYKRWTQFGLLSSHSRYHGNVEYKVPWIYDEEAVE
                     VTRKFAKLKMKLMPYLFKYVVEAKNTGIPMIRPMVLEYSDDETCIYLDRQYMFGEGLL
                     VAPIFSDTGDVSYYLPEGRWTNLLNNKVLEGRRWYKENHDYMSLPLMVKDNTIIPIGY
                     NDKKPDYDYLKDLEINIFELDENNRIETILYNSLGKEVGKVSAIKIGNKISVQTKGIS
                     GDYKIVLRNINATSENTKCKYDLEIGTVAQVKDSEVIFTVKNNF"
     gene            complement(38480..39529)
                     /locus_tag="KRN00_000033"
     CDS             complement(38480..39529)
                     /locus_tag="KRN00_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1825933.1"
                     /translation="MKKIRKLATKLLITTMVLISGMSMTAYGMTAKEVTTKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIECYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLTHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAFGELGDIKDKHVMYEGVRCIVINSSVNTVTFIGSKSNLDPSKLVIAVIGFM
                     NTPYGMFALAPEGNPVEYPFEYDKPFSLDFSGKNRSGVELAKYCKKNDVTIKIEITDK
                     EANNGIGQVMYIRYE"
     gene            complement(40164..41573)
                     /locus_tag="KRN00_000034"
     CDS             complement(40164..41573)
                     /locus_tag="KRN00_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012059035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1825934.1"
                     /translation="MSRFPENFLWGGAVAANQCEGAYNVDGKGLSIQDVTPNGIMTPR
                     TEKPTEDNMKLVGIDFYNRYKEDIKLFAEMGFKVFRTSIAWSRIYPKGDELEPNEKGL
                     KFYDDLFDECRKYDIEPLVTLSHYETPLYLAEKYDGWISRDLIDFYCRYVTTVFKRYK
                     DKVKYWLTFNEINSIVHEPFLSGGINTPKEKLTKNQIYQAIHHELVASAKAVKIGHEI
                     NPEFKIGCMVLSMPVYPLTPNPDDVICAMEKEHENLFFADIHVRGKYPSYSKRYFRKN
                     NIHIDVMDEDIEILKNTVDFISFSYYMSICESSDKTIKGSKGNIMGGAKNPTLKESEW
                     GWQIDPQGLRYVLNQFYDRYQKPLFIVENGFGAFDELIVGENGEFTVNDDYRIDYLRN
                     HLKQVAEAIDDGVDLMGYTTWGCIDLVSASTAELKKRYGFIYVDRNDDGSGTLNRYKK
                     KSFNWYKKVIETNGEYLFE"
     gene            complement(41691..43547)
                     /locus_tag="KRN00_000035"
     CDS             complement(41691..43547)
                     /locus_tag="KRN00_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009169876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1825935.1"
                     /translation="MSTKYCDLSKEIIEGVGGLENISYVTHCATRLRFKLKNIGKANT
                     ENLKKNNGVITVVESGGQYQVVIGNHVSEVYNQLVKGTILETQVDNIEDKEKAKEKLI
                     DRFISAISAIFSPLMMALSGAGMLKALLILGNTVGVLQENSGAYMILYAAADAIFNFL
                     PIALAFTSAKYFKANQFLAFIIGASLVYPNIVALYNEGQSINFLGLSVILVSYTSSVI
                     PAIISVWALAKVEAFLNKIIPSILKSFLVPLLCISIIVPLTYLTIGPVTSYAGVYLAD
                     GYKWVMSINPIIAGGLVSVIWPTVIIFGLHWGFVPIVLNNIATYGRDTLFVITGPNNF
                     SQAGACLGVFLKTKDKDLKSIAGPAAVSAVLTGITEPAIYGVNLKFKKPFIIASIFSG
                     VAGAITAAAGTGVGAFIGTSLITLPAYIGVGFIGFLIACAIAYVGSAVTTFIWGFNDN
                     MILEGLTYKSVLDSKKDSVVLKSALQGELVSLKDIPDQCFSEGAMGQGIAIKPYKGEL
                     YAPADGEVKFVFPTKHALGFETNEGVEILMHIGIDTVELEGKYYEMHINAGDKVKAGD
                     LLVTFDIDKISEAGYSTITPIIVTNSSEFQDIIISTNDKELMIESDLLTAVI"
     gene            complement(44021..45298)
                     /locus_tag="KRN00_000036"
     CDS             complement(44021..45298)
                     /locus_tag="KRN00_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4038 domain-containing protein"
                     /protein_id="HBH1825936.1"
                     /translation="MSRLKVASDNRTFTLDKEHFFYLADTCWSAFTNIDFNEWRFYLE
                     KRKQQGFNTLQVNILPQWDRSAKHNELLPFDIKDDGAFDYSTLNKLYFENARKMCLLA
                     KEYGFQLALVVLWSNYVPGTWASAIMDKNIIPISFLSTYFDIVNKTFNDMNPIYLISG
                     DTDFGKEESIEYYNKALEFFNKVSPNTLKTLHIRGRLEEIPEILVSKIDFYMYQSGHN
                     SSFTNMPYYLAEVFYSKYPCKPILNSEPCYEQMGYSRKVYGRFNDYDIRKAGWQSVLS
                     GGCAGLTYGAHGIWSWHTNDSTFFMGIGEAFDSPLLWQSALQLPGAFDYGMIKYLLEQ
                     NNLKNIIPKNNLVVNDTDEIRYATNYDKSSVVLYIPINTNVKISENLSEYKFHLFDLE
                     TKNILIPLIEFKKDSTLFKMHSCNKDIVIIGQK"
     gene            complement(45347..46372)
                     /locus_tag="KRN00_000037"
     CDS             complement(45347..46372)
                     /locus_tag="KRN00_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH1825937.1"
                     /translation="MNSKTIMQDIAKLAGVSPGTVSNALNNRKGVGKETKERIIKIAE
                     EKGYFRNQKKNEDNAIRLIVFKKHGYVVSDTPFFSALIEGCERECRNNGYELLISHVR
                     DDVNSKENIDTIIRQKNVDGILLLATEMNEADLRFFENLSISIPIVIVDSYHETKSSD
                     YVCINNVSGAYSAVKYFVEKGHKKIGYLGSSRSIKNFEYRATGFDKALNDLNIKQNQE
                     YKFLLEPTIDGAYNDMNKIIDEKVELPTALFAFNDIIALGAMKAMNEKGIKIPEDVSI
                     IGFDDITFSALANPALTTIKVQTVEMGKIAVNRLIDKIDNQINLKLKIEVETELIERD
                     SVKDINK"
     gene            complement(46524..47948)
                     /locus_tag="KRN00_000038"
     CDS             complement(46524..47948)
                     /locus_tag="KRN00_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose/L-arabinose isomerase family protein"
                     /protein_id="HBH1825938.1"
                     /translation="MIEYKIKLGVAPTRRNIFSKKEAIRYKQLVSKKLKSMNIDFVDI
                     EDINEEGLLFKESDVEKVVDKFKQEKVDALFFPHCNFGTEDLVAKVAHKLHLPVLLWG
                     PRDGAPLEDGTRLRDSQCGLFATGKILRRFKIKFTYIPNASLEDEAFERGVNNFIAAV
                     NVVKELKNLRILQISTRPLSFWTMMCNEGELLEKFGVQINPISLSEFVSSVKEIESKN
                     NEKLKETIQFLRENLEINVEDESVVRVAALKLSFNLLTEKYGCKAVAIQCWNALQEEL
                     KIMPCMANAILTDEGIPVVCETDIHGAITSVIAQSAAMGKTPPFFADWTVAHPTNKNG
                     ELLQHCGCYPISLTKEGEKAKFGVPFALESRCVGSSFAEIKGGNISLLRFDGDNGEYS
                     LLLGHAKGIEGPYIQGTYLWVEVENLTRLEDKLVTGPYVHHCVGIHHDVLPAIYEACK
                     YLPDLNLDFYDNVEEDVKAWIRGE"
     gene            complement(47959..49473)
                     /gene="glpK"
                     /locus_tag="KRN00_000039"
     CDS             complement(47959..49473)
                     /gene="glpK"
                     /locus_tag="KRN00_000039"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004618113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH1825939.1"
                     /translation="MDKKYILTIDQSTSGTKVLLIDSRGIIINKLSKKHTQYYLNNSW
                     IEHDPIEIYSNVICLLKEIIISHELCTGDIAGISITNQRETVVIWDKNTGKPVYNAIV
                     WQCRRTSDICKNLSVYKNEIQEKTGLKLDPYFSATKVKWILDNVDGARAKAERGDLLL
                     GNIDSWLVWNLTNGKSHATDYTNASRTLLLNIRDLKWDDSLLSIFDIPRSMLPKIYPS
                     DEIFGETNIEGYFSENLKISGVIGDSQGALFGQRCFEVGMAKSTFGTGNSIMINVGEN
                     FIPSQNGVVSTVGYITKNIVSYAVEGIVNSSGDTINWIKNELGLFSDFEEFNKAVEEV
                     KNNDGVYFIPAFIGIGVPFWKPNARASIVGISRNTTKKHIMRAAMESIAYQVKDAIDI
                     LELESNITVKNLSVDGGVTVNDIYNQFLADLLDCKIAKNKNEELSALGSAYLGGIGLG
                     IWNGIEEIKNLHKNIKNYTSNVNEENRENLYRKWKNAMKSVLYMTDLNSQNVNL"
     gene            complement(49485..50426)
                     /locus_tag="KRN00_000040"
     CDS             complement(49485..50426)
                     /locus_tag="KRN00_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004618111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH1825940.1"
                     /translation="MNNVANRKVICDALVDIAKYDKDIIVLTSDSRGSASMSEFAELY
                     PEQFVEVGIAEQNLVGIASGLASCGKKTYVASPACFLSMRSIEQIKIDVAYSKNNVKL
                     IGISGGISYGALGMTHHSLQDIAVTRAIPDIQVLLPADRYETKKMIQELYKSDIPAYI
                     RIGRNPVEDVYENEDFDFKIGRANELHSGNDITVIATGETVRIALDAAIELEKHGIEC
                     RVINMHTIKPLDKEAIIKSSKETKGIITIEEHSIYGGLGAAVSEVVVQNIPVKMQVLG
                     IADESPISGNSKEVFNYYGLNSENIVKIAKEMLFSEN"
     gene            complement(50427..51248)
                     /locus_tag="KRN00_000041"
     CDS             complement(50427..51248)
                     /locus_tag="KRN00_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015394896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH1825941.1"
                     /translation="MNKQIKRLEEKSNQIRKEILDVVYNAKAGHIGGAMSSTDILTTL
                     YYHIMNISPENAKDSNRDRFILSKGHIAEALYCILADKGFFSRDKLKTYSQFNSTLIG
                     HPNKKNEGIEVNTGSLGHGLSLAVGMAIAGKRDKKSYRVFTLMGDGELAEGSIWEGAM
                     AASHYKLDNLVAIIDRNKLQISGTTEEVMTLENLQEKWQSFGWKVVQVDGNNITELVE
                     VFDKIPLKKNKPTMIIANTIKGKGISFMENNVKWHHGVLTEEQYIKAVEDLKEGK"
     gene            complement(51829..52350)
                     /locus_tag="KRN00_000042"
     CDS             complement(51829..52350)
                     /locus_tag="KRN00_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH1825942.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKINDIQMVDGKGIFIEELEKLLKEYNLK
                     IPIVGLDEFREDK"
     gene            52516..53082
                     /locus_tag="KRN00_000043"
     CDS             52516..53082
                     /locus_tag="KRN00_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1825943.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKSTSSYS"
     gene            complement(53604..54473)
                     /gene="gatY"
                     /locus_tag="KRN00_000044"
     CDS             complement(53604..54473)
                     /gene="gatY"
                     /locus_tag="KRN00_000044"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH1825944.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIREVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(54493..56409)
                     /locus_tag="KRN00_000045"
     CDS             complement(54493..56409)
                     /locus_tag="KRN00_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBH1825945.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSSVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGL
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(56412..57332)
                     /locus_tag="KRN00_000046"
     CDS             complement(56412..57332)
                     /locus_tag="KRN00_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBH1825946.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLEDISYLSISGSLPPGIDDNYYEDIFKICENKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKSIRVRKVV"
     gene            complement(57434..58186)
                     /locus_tag="KRN00_000047"
     CDS             complement(57434..58186)
                     /locus_tag="KRN00_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1825947.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(58482..59099)
                     /locus_tag="KRN00_000048"
     CDS             complement(58482..59099)
                     /locus_tag="KRN00_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1825948.1"
                     /translation="MNVIKKFIFVILIINILGCGISLILQSSLGSDAITLLNEGIHIK
                     LGISYTIAGLIYNGTLLLIALLLNKKSLGLGSCVYVLVAGIFIDLYIYLLLDFNISSL
                     GIIIRIMSFIIGHILMCSGFAMLIKFDIGMSPLDAILIYIEGKFKYPYKVLKTIADVI
                     FLILGVYLGGNLGFGTIFSILCTGTTISIVSKMISVNKKRYYSNI"
     gene            complement(59198..60643)
                     /locus_tag="KRN00_000049"
     CDS             complement(59198..60643)
                     /locus_tag="KRN00_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1825949.1"
                     /translation="MIKLGKFPKDFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVQEARYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVIEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNINNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDNYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKKRYKKDSFYWYQNVIRTNGEELKEK"
     gene            complement(60665..61018)
                     /locus_tag="KRN00_000050"
     CDS             complement(60665..61018)
                     /locus_tag="KRN00_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1825950.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(61047..62294)
                     /locus_tag="KRN00_000051"
     CDS             complement(61047..62294)
                     /locus_tag="KRN00_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1825951.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMEIMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(62302..62619)
                     /locus_tag="KRN00_000052"
     CDS             complement(62302..62619)
                     /locus_tag="KRN00_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1825952.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            62861..64774
                     /locus_tag="KRN00_000053"
     CDS             62861..64774
                     /locus_tag="KRN00_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1825953.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGEFILSSKKGYKVNLNNNCQTKVDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     DLFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLIGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIMYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYINNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIS
                     DRCHIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIKFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(64897..66051)
                     /locus_tag="KRN00_000054"
     CDS             complement(64897..66051)
                     /locus_tag="KRN00_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBH1825954.1"
                     /translation="MKILISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLNSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(66331..68946)
                     /gene="mngB"
                     /locus_tag="KRN00_000055"
     CDS             complement(66331..68946)
                     /gene="mngB"
                     /locus_tag="KRN00_000055"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH1825955.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPERKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLVAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLLNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGYIKRSVYDDAMEVWQQEEWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLPTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKQEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(69090..71015)
                     /gene="mngA"
                     /locus_tag="KRN00_000056"
     CDS             complement(69090..71015)
                     /gene="mngA"
                     /locus_tag="KRN00_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBH1825956.1"
                     /translation="MEFKKITNENLVFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEY
                     LEAVMYRETLSPTGFERGLAIPHGKSKSVKEASFAAMTLETPIENWESVDPDNKVEII
                     FLIAVPENEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKE
                     EIRIQNESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHT
                     PDIIKRADAIIYATDVAPKNTERFEHLPNIKTSVSAPLKRAKEIIYEALEVAQKQGKG
                     DYIEKSSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQEL
                     YNQEGSWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGF
                     LGGMLGGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAA
                     LNNGLINWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAI
                     FASVKMVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVI
                     PSLVAGSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIIS
                     AILLIITRKQKNQRKIH"
     gene            complement(71145..71870)
                     /locus_tag="KRN00_000057"
     CDS             complement(71145..71870)
                     /locus_tag="KRN00_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1825957.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAINKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(72133..72912)
                     /locus_tag="KRN00_000058"
     CDS             complement(72133..72912)
                     /locus_tag="KRN00_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBH1825958.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEENVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(72905..74332)
                     /locus_tag="KRN00_000059"
     CDS             complement(72905..74332)
                     /locus_tag="KRN00_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1825959.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            74723..75445
                     /locus_tag="KRN00_000060"
     CDS             74723..75445
                     /locus_tag="KRN00_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1825960.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKAGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            complement(75593..76774)
                     /locus_tag="KRN00_000061"
     CDS             complement(75593..76774)
                     /locus_tag="KRN00_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1825961.1"
                     /translation="MKHNFDEVYNRKGTYCTQWDYIQDRFGKKDLIPFSISDTDFTVP
                     KPVYEKLQEILQHQIYGYSRWNHNDFKGSITGYYNRRFEAKIESDWVLYSPSVMYSVA
                     LLLRLLCNNKKKVATFNPMYDAFFSVIEENGFELEKIQLYEKDGKFNIDFDEFEDSVK
                     NCDVLLLCSPHNPTGKVWKEVELEFLINTCKKYNIKIISDEIHADIIMPDNKHLPIVK
                     YLREYKELYLVSSGSKTFNYPGLIGSYAVIANKNIYDEFLSITRRRDFLNSVSLPGMY
                     ATMVSYNECDYYIEQLVEYIDNNLSYVSQFIKENFEDIKFTKPEGTYLAWIDCRDVPF
                     TCEEIQDSLINIGGVGIMRGEVYGSEKYLRLNCGCPREKLKKGLERFKQSIDYLYFNN
                     K"
     gene            complement(76995..78332)
                     /locus_tag="KRN00_000062"
     CDS             complement(76995..78332)
                     /locus_tag="KRN00_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1825962.1"
                     /translation="MFKKFEQFMNKHLTPIAQRMDKQHHLSAIKKSMVAMTPILIIGS
                     LSLMPEAIGNLTEKAIGANAITSFITNNMDSLQIPFYLTIGMMGFLVCMCITYFLSEH
                     YKLYVPGAMSLAAVGFLLMSFNFTEDGGMDIKYMGTKGLFIAMVAGVLAVELYRWCKK
                     KNFTIRMPESVPDFVSSSFELIPTTVIIVGVFIGIRIITLQVFGVLPPEILTQFLAPL
                     VGSLDNPFTFAFITFLGITLFFFGIHPSVLSPITAPITAQFLAENLEAMAVGQSLPHF
                     YTGGMVSAFANFTGTGVTFGLVFWYLMSKRVDFKRIGQVSLVPALFGINEPILFGGPI
                     VLNPTFFLPFVIGGTILGTFPAFLMNAGILAKPFFNPPYLGVFIEGFLVNGHWLTPIV
                     QAFQMVGSILIWYPFYKMYEKQCDERDTKQVQEIQEESVISPEDLGLLGDLDF"
     gene            complement(78371..78697)
                     /locus_tag="KRN00_000063"
     CDS             complement(78371..78697)
                     /locus_tag="KRN00_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002607219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1825963.1"
                     /translation="MRIILCCAGGFSTTMLMKNMENVVKNSKKLNDDDFEFKAIPVDL
                     LKNEVDNCDVLVIGPQIAHKLDYIKPILEPKNVPYVIIDQNTYGKMDGATALKMALIA
                     HKKANM"
     gene            complement(78700..79020)
                     /locus_tag="KRN00_000064"
     CDS             complement(78700..79020)
                     /locus_tag="KRN00_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002610126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1825964.1"
                     /translation="MENLEMKIMEIIVSSGDSKSKSFEALNKVKEGDYEGARACIEEA
                     RKIDIEAHNAQTALIQSELSGDCESKSMVSLLMVHAQDHYMTSQLSRDLIEKLIDIFE
                     SKEA"
     gene            complement(79038..80066)
                     /gene="ypdE"
                     /locus_tag="KRN00_000065"
     CDS             complement(79038..80066)
                     /gene="ypdE"
                     /locus_tag="KRN00_000065"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1825965.1"
                     /translation="MSIDYLKKLCEADGIASNEQEIRELLAENINGEISFDNLGSMIV
                     HHRGNGVKMMFCAHMDEVGFMVRHISDIGMLHLINVGGVKDSAKSFQKVNISKVDGTK
                     VKGLINCSYDENNKVKDLYADIGVSTAKEVEDLGINIGDMVCFASESEMLNENVLMAK
                     ALDDRIGCYILKEIDRRVNQIKKNDNDIYIVYTSSEEVGIRGGKTTSKVVNPDIVFAV
                     DVACAPDLIRNYTNQRQLSKGCMIVHYDKTMIPNKKFLNYMKDLATKYDIKFQCDMFS
                     GGGTDAGNAHLVNEGKLAIVLGVPLRYCHGNYSMVDMRDVEEVINLCTAVINDMNMEK
                     YNNILKFI"
     gene            complement(80078..81919)
                     /locus_tag="KRN00_000066"
     CDS             complement(80078..81919)
                     /locus_tag="KRN00_000066"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012579.1,HMM:NF013070.1,HMM:NF019884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1825966.1"
                     /translation="MRILKIINDLENTNKYLSIAYFIDKYSVSKRTLQNDFSYLSKVS
                     SNKGFKIIQKRGLGYLLEIEDNTLFKKFKVELFEYLDQPKLNVESIIACLILNEDYIT
                     IDRILEELKTSRSVIKGYKEDIDSYLKKYNLKLERKSHYGLKIINSMKERRKLIVELY
                     IKENEIIKKYIDSKLENDFKEVQEKFINKLKENNLVINYIELKEILSWLKVTMYIDRQ
                     SKLLELDDSTNEYELNLSSEDYKILKSLIKKKARKKFRRQKGADNLRDDLEDFLKQFD
                     EENNTYFNEDEEFKRSLLNHLTELLERSTFSISYQNPLIDEIQIKYPVAFNIAILLGK
                     IMYKKYNVEIQRDEIGFIATYFAMNMEKQAIYKFRKYNSIAIVCSSGGGSAQLIKFKI
                     SSLFENTNIKTFSLIQMKELEKFNPDIIFSICELDIKLEVPIVYIKELLDDYDILRIK
                     ELIMFEKFKEYSLENKGQAFICKFLRNDYFNIDNDSIDYIKCLEDMSKNIELKGAGNY
                     GYSENVLKREYFATNIYINGVAIPHPIDIDGNENLISVKILQNPIDFKGKKVSLIFMI
                     CLKKENIGLYKKISSSLYEIMNDIETVQLLVNAKTFKEFVALINQRI"
     gene            82426..84093
                     /locus_tag="KRN00_000067"
     CDS             82426..84093
                     /locus_tag="KRN00_000067"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBH1825967.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMNDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(84189..85508)
                     /locus_tag="KRN00_000068"
     CDS             complement(84189..85508)
                     /locus_tag="KRN00_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1825968.1"
                     /translation="MEKCIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLIKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYADKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVDVK"
     gene            complement(85549..86295)
                     /locus_tag="KRN00_000069"
     CDS             complement(85549..86295)
                     /locus_tag="KRN00_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH1825969.1"
                     /translation="MKKLVKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVASGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(86539..88548)
                     /locus_tag="KRN00_000070"
     CDS             complement(86539..88548)
                     /locus_tag="KRN00_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1825970.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKGNIIICNNSLGDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYSITEGEVRGILNMLKDLDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(88986..90419)
                     /locus_tag="KRN00_000071"
     CDS             complement(88986..90419)
                     /locus_tag="KRN00_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1825971.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYENVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYTFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(90435..91859)
                     /gene="ascB"
                     /locus_tag="KRN00_000072"
     CDS             complement(90435..91859)
                     /gene="ascB"
                     /locus_tag="KRN00_000072"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1825972.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEDGRGLANVDVTPQGKDRFPV
                     LAGKMKMFECDDEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGVE
                     DVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKGKVKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMLAAGNTYPNTCNPLDVWKSIEKDRENYFFIDVQSRGEYPTY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPKVNILTEGNVFASL
                     KNPYLDASEWGWQIDPLGLRITMNSLYDRYQKPLFIVENGLGAVDNPDENGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFAWYKKVIESNGEEL"
     gene            complement(91946..93862)
                     /locus_tag="KRN00_000073"
     CDS             complement(91946..93862)
                     /locus_tag="KRN00_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1825973.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQELITVLA"
     gene            complement(93936..94796)
                     /locus_tag="KRN00_000074"
     CDS             complement(93936..94796)
                     /locus_tag="KRN00_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1825974.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(95150..96337)
                     /locus_tag="KRN00_000075"
     CDS             complement(95150..96337)
                     /locus_tag="KRN00_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1825975.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFDNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKF
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSGEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(96351..97742)
                     /locus_tag="KRN00_000076"
     CDS             complement(96351..97742)
                     /locus_tag="KRN00_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBH1825976.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(98337..100037)
                     /locus_tag="KRN00_000077"
     CDS             complement(98337..100037)
                     /locus_tag="KRN00_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1825977.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(100009..101412)
                     /locus_tag="KRN00_000078"
     CDS             complement(100009..101412)
                     /locus_tag="KRN00_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1825978.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGIYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIIDIYKDLKLLYVKPDSELI
                     NKLSSAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(101676..102167)
                     /locus_tag="KRN00_000079"
     CDS             complement(101676..102167)
                     /locus_tag="KRN00_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1825979.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLKDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(102193..103005)
                     /locus_tag="KRN00_000080"
     CDS             complement(102193..103005)
                     /locus_tag="KRN00_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1825980.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEVMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSEEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALKKILS"
     gene            complement(103018..104169)
                     /locus_tag="KRN00_000081"
     CDS             complement(103018..104169)
                     /locus_tag="KRN00_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1825981.1"
                     /translation="MINFYQPSRINFGQGTLSELPRIIGKYGKKCLLVTTPNVEPLDK
                     LYKRVTLNLIEKGIEVVHFDRVEPNPTVELINEGFELAKKESVDVVLAVGGGSSIDTA
                     KVLALTFGLEKIDWDYMFSTYTNPFKIYDKVSEKELPLIAVSTTSGTGSQVTQAAVIS
                     RGSEKNTIFHQNCFSKECIVDPELMLTLPERITASTAFDAFTHAFESYINPNANDFTE
                     IMSEKSMELVINYLPKVMEDKNNIEYRTKLAVADTLGGSSLANAGAAAPHPLSEIIGG
                     VTHIPHGEALAIVFPKFAEKFYKDNIEKFAKVARMLNQELEKVEDDEAAKTLGNEIES
                     FLKRVGLKTKMSEFNVTKEQLEQITSCPVLGFLPFGKKEDLVEILEKSY"
     gene            104439..105080
                     /locus_tag="KRN00_000082"
     CDS             104439..105080
                     /locus_tag="KRN00_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBH1825982.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            105106..106650
                     /locus_tag="KRN00_000083"
     CDS             105106..106650
                     /locus_tag="KRN00_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1825983.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLREAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(106850..107476)
                     /locus_tag="KRN00_000084"
     CDS             complement(106850..107476)
                     /locus_tag="KRN00_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1825984.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(107611..108327)
                     /locus_tag="KRN00_000085"
     CDS             complement(107611..108327)
                     /locus_tag="KRN00_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBH1825985.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDSGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRADNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            108764..109978
                     /locus_tag="KRN00_000086"
     CDS             108764..109978
                     /locus_tag="KRN00_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH1825986.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITDEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            110588..111916
                     /locus_tag="KRN00_000087"
     CDS             110588..111916
                     /locus_tag="KRN00_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1825987.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIKIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINPLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(112044..113234)
                     /locus_tag="KRN00_000088"
     CDS             complement(112044..113234)
                     /locus_tag="KRN00_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1825988.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNLPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETSRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVANAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSVSQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(113340..114719)
                     /locus_tag="KRN00_000089"
     CDS             complement(113340..114719)
                     /locus_tag="KRN00_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1825989.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTLEELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            complement(114750..115958)
                     /locus_tag="KRN00_000090"
     CDS             complement(114750..115958)
                     /locus_tag="KRN00_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1825990.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLL
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            complement(116983..118437)
                     /locus_tag="KRN00_000091"
     CDS             complement(116983..118437)
                     /locus_tag="KRN00_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1825991.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDKKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFQNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            complement(118457..120328)
                     /locus_tag="KRN00_000092"
     CDS             complement(118457..120328)
                     /locus_tag="KRN00_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1825992.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASILALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSVTLTIFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPIALNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVNGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            complement(120318..121178)
                     /locus_tag="KRN00_000093"
     CDS             complement(120318..121178)
                     /locus_tag="KRN00_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1825993.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGINLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            complement(121773..122177)
                     /locus_tag="KRN00_000094"
     CDS             complement(121773..122177)
                     /locus_tag="KRN00_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH1825994.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            complement(122369..123556)
                     /locus_tag="KRN00_000095"
     CDS             complement(122369..123556)
                     /locus_tag="KRN00_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBH1825995.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(123588..124013)
                     /locus_tag="KRN00_000096"
     CDS             complement(123588..124013)
                     /locus_tag="KRN00_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1825996.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            124471..125220
                     /locus_tag="KRN00_000097"
     CDS             124471..125220
                     /locus_tag="KRN00_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1825997.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(125386..125751)
                     /locus_tag="KRN00_000098"
     CDS             complement(125386..125751)
                     /locus_tag="KRN00_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1825998.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(125767..126543)
                     /locus_tag="KRN00_000099"
     CDS             complement(125767..126543)
                     /locus_tag="KRN00_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1825999.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(126990..128417)
                     /gene="ascB"
                     /locus_tag="KRN00_000100"
     CDS             complement(126990..128417)
                     /gene="ascB"
                     /locus_tag="KRN00_000100"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1826000.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(128478..130406)
                     /locus_tag="KRN00_000101"
     CDS             complement(128478..130406)
                     /locus_tag="KRN00_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1826001.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPNLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIV
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVDAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(130551..131393)
                     /locus_tag="KRN00_000102"
     CDS             complement(130551..131393)
                     /locus_tag="KRN00_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1826002.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(131907..134408)
                     /locus_tag="KRN00_000103"
     CDS             complement(131907..134408)
                     /locus_tag="KRN00_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826003.1"
                     /translation="MIFHEVYKIYSKNSLKNNKLLKISCIISIVFATAILLFTRVLTD
                     TYSSEVKRNMAITNGGDIKIQNIEYNKYYFTSEQIDKLEELKDKEAIDFQLGSSMNTN
                     ILSNGMIESTELTVVNNIKMQNTYLKLRNEKDIVLSQKTANKLNVNIGDKVFLKLHSS
                     VYDDTYFKVSDIIPKKFSLSTAQKEAEVGQEVVGESYVYLPNETKYNVAYINIINKEN
                     VKNIKNEIKNVFKNHFEVRTTDELEQSIIKRISMQLDSINLIGAISLLITGICLCSTF
                     IVFILNRIHDFSTFKALGIKKRSLSFLVFTELMSITIKGIIIGIILGIPITIFYINLQ
                     HINLFNISILSIIKNIFISIVIIIIETSIFSLIPISFVKKIPYEGINRDNSMLSSYKF
                     NFIPDIILVIFLTSISFTIYVKSFLGIFFILGLILLDLLVYSLIYALLKMVCLIKKII
                     KGKYSITFIYLNNDCKTNAFSSSLLTITIIFVLLLFMISEITFAMFSNYEVDNSIKNS
                     IVYQTTLEGKLITDKKLIENDIDYFQYYPIKIDSIESVNNISVNDYIEKIPYENRKDV
                     MNDLNDLSVDLFNTKQTILKSDLEYGNWFKENDKENSIIINNYLHRYLIDYKLGDTVK
                     LRINGKKIDFKVIGFLSPKSLNKGVDLGYININENISPKTLDLSKNQPVIYFFKEKLD
                     NTLLSKLLHNDKYANLEDYNDFAYSMKTYVDDQKSLLLNIIFAVSLSSILLILTSQII
                     IFIRRVLDYQIMYRVGMSKRKLIKIGLLEMIIVSIIQSILIAIFYELFRFLLISLLQR
                     AYNINYLLILIEFLVVLSINCFIFILAQRNIKLDL"
     gene            complement(134420..135079)
                     /locus_tag="KRN00_000104"
     CDS             complement(134420..135079)
                     /locus_tag="KRN00_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003410138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826004.1"
                     /translation="MIIEVSNLSKVVDLLNTELTILRNIDLYIEEGEFVSIMGASGSG
                     KSSLISILSGLDKNYTGNVKVCGENLSKLTDDELAEYRNRKIGIVFQSFNLITSMSVE
                     ENIKLPLIFSDNKDYKIVDKMIKKVGLTSKTKNNIKQLSGGEKQRVAISRALVCSPNI
                     LFADEPTGSLDSTNSHAIMKLFKNINNEYGTTIVMVTHDIQMAEYSDRIISIKDGTII
                     K"
     gene            complement(135650..135802)
                     /locus_tag="KRN00_000105"
     CDS             complement(135650..135802)
                     /locus_tag="KRN00_000105"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826005.1"
                     /translation="MEKKFDTYIPTTGRWSLGCTIGFIMYKIVHVKVISPLGWWLINN
                     MINRIV"
     gene            complement(135993..137396)
                     /locus_tag="KRN00_000106"
     CDS             complement(135993..137396)
                     /locus_tag="KRN00_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1826006.1"
                     /translation="MKNKYEDVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKNKKNSI
                     LNNIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYF
                     MPIILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYAASV
                     IPALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLA
                     SIINLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCA
                     NLAQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGA
                     GIAGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFG
                     VEKNVKEGIGKLRKCVK"
     gene            complement(137435..138106)
                     /gene="pgmB"
                     /locus_tag="KRN00_000107"
     CDS             complement(137435..138106)
                     /gene="pgmB"
                     /locus_tag="KRN00_000107"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH1826007.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAHRILESLGIKDEFDCIVNPSLLERGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINSANMTSIGVGKKEVLGKCDHIVEDTSLLNYNTLLQAWSK
                     KINLA"
     gene            complement(138108..140498)
                     /locus_tag="KRN00_000108"
     CDS             complement(138108..140498)
                     /locus_tag="KRN00_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH1826008.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHTRILDLNEGILKRSFIWENSCGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKIDVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRKRARELGINKGCLYSWRTINGNECSAYYPAGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVELGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHATNMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(140524..141972)
                     /locus_tag="KRN00_000109"
     CDS             complement(140524..141972)
                     /locus_tag="KRN00_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1826009.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERHNLFFSDVQVRGVYPSF
                     MSYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(142377..143264)
                     /locus_tag="KRN00_000110"
     CDS             complement(142377..143264)
                     /locus_tag="KRN00_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1826010.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(143364..143813)
                     /locus_tag="KRN00_000111"
     CDS             complement(143364..143813)
                     /locus_tag="KRN00_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1826011.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(143803..145710)
                     /locus_tag="KRN00_000112"
     CDS             complement(143803..145710)
                     /locus_tag="KRN00_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1826012.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDELMYIYIFLVSSGFSSESNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGMYLEDNIYFNFDAAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNINNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(145978..147873)
                     /locus_tag="KRN00_000113"
     CDS             complement(145978..147873)
                     /locus_tag="KRN00_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1826013.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAELGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVITALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(147909..148787)
                     /locus_tag="KRN00_000114"
     CDS             complement(147909..148787)
                     /locus_tag="KRN00_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBH1826014.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(149330..149500)
                     /locus_tag="KRN00_000115"
     CDS             complement(149330..149500)
                     /locus_tag="KRN00_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826015.1"
                     /translation="MSALLYGVCNKPISISIVTNMQEFKIGVSMDYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(149897..150109)
                     /locus_tag="KRN00_000116"
     CDS             complement(149897..150109)
                     /locus_tag="KRN00_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826016.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAMDIAKVFDTTVENLFEFIEEE"
     gene            complement(150110..150526)
                     /locus_tag="KRN00_000117"
     CDS             complement(150110..150526)
                     /locus_tag="KRN00_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826017.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLATKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(150594..151007)
                     /locus_tag="KRN00_000118"
     CDS             complement(150594..151007)
                     /locus_tag="KRN00_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826018.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKEGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLISVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(151839..152468)
                     /locus_tag="KRN00_000119"
     CDS             complement(151839..152468)
                     /locus_tag="KRN00_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBH1826019.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(152547..153509)
                     /locus_tag="KRN00_000120"
     CDS             complement(152547..153509)
                     /locus_tag="KRN00_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1826020.1"
                     /translation="MAKIDNMMSILWMLNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNNLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(154190..157855)
                     /gene="cbpA"
                     /locus_tag="KRN00_000121"
     CDS             complement(154190..157855)
                     /gene="cbpA"
                     /locus_tag="KRN00_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBH1826021.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAGGDANAGNAEGDANAGNAGGDANAGNAGGDTNAGNPEGDANAGNAGGD
                     ANAGNAGGDANAGNAEEDANAGNAEGDANAGNAEEDSNAGNAEEDSNAGNAEGDMNAL
                     VVEEATAEDPTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIV
                     IPKDVKAELIFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGM
                     RAGKGTTLIIDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRG
                     SLKVVGNYYSAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGD
                     ITINGGTITAKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSY
                     GGAHGSAFGDGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSL
                     KATTFKSLGGAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYG
                     APSYTDDQGVLYLWFSEQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQ
                     YEEFTIDDTPPYLIIKRYDGLPFEEDVEKSFLDWILKDGGIPIITPKGEKLTDKKFMT
                     ISSQRLNEETMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYK
                     AEIIPADTETSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYIN
                     GKEYKDPVELKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIE
                     GSEDEKKLKLDVTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGE
                     WKPSTEGGNGDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGS
                     GGYDTGNPNLNKPDPDNGGNSKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNG
                     GNSKPDSGNGGNSKPDPDNGGNGKPDPDNGGNGKPDPDNGGNNKPDPDNGGNSKPDPD
                     NGGNSKPDIDIDIDTDGDGKPNINIDTDGDGKPDINIDTDGDGKPDVNIDIDGDGKPD
                     VNIDIDGDGKPDINIDTDGDGKPDINIDTDESLDSNVGQNVQTGDQSNIMLDLALMFT
                     SLFFLIKNLINKYLRRK"
     gene            158124..158695
                     /locus_tag="KRN00_000122"
                     /pseudo
     CDS             158124..158695
                     /locus_tag="KRN00_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
     gene            complement(159705..160367)
                     /locus_tag="KRN00_000123"
     CDS             complement(159705..160367)
                     /locus_tag="KRN00_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826022.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(160384..162938)
                     /locus_tag="KRN00_000124"
                     /pseudo
     CDS             complement(160384..162938)
                     /locus_tag="KRN00_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(163172..163366)
                     /locus_tag="KRN00_000125"
     CDS             complement(163172..163366)
                     /locus_tag="KRN00_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBH1826023.1"
                     /translation="MRKYKAILLTLIISIIAIIGFIIYNNYFRKWNEAEKYIDKYMTY
                     QGVSGDDIERITKEKYTKEN"
     gene            complement(163378..163557)
                     /locus_tag="KRN00_000126"
     CDS             complement(163378..163557)
                     /locus_tag="KRN00_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826024.1"
                     /translation="MIHVEISEKEFFRKIEEVFDKGEGNVEVDNLGDIKIQVKKFDDK
                     TKSLELKLIKEFKLK"
     gene            complement(163562..163819)
                     /locus_tag="KRN00_000127"
     CDS             complement(163562..163819)
                     /locus_tag="KRN00_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826025.1"
                     /translation="MSKKISESIENSGLRVAENKSDGSFVLSLENLEYTKEQSSQVLH
                     YSMTKDKKGTKEILSIQCVKDFSYNEKLSEGDKFIMAIYNI"
     gene            complement(163792..163998)
                     /locus_tag="KRN00_000128"
     CDS             complement(163792..163998)
                     /locus_tag="KRN00_000128"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826026.1"
                     /translation="MINNEFSIYKVDYMKIKKITITMVIAISLTLGLITGCTNKVSDT
                     NEKIYTIEQISSIKKTCQRKYQNQ"
     gene            complement(164081..165474)
                     /locus_tag="KRN00_000129"
                     /pseudo
     CDS             complement(164081..165474)
                     /locus_tag="KRN00_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            complement(165468..165713)
                     /locus_tag="KRN00_000130"
     CDS             complement(165468..165713)
                     /locus_tag="KRN00_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH1826027.1"
                     /translation="MLIHTKNKTFDAICILEKIEKDLNIEELVRCHKSYIINLNYVEN
                     IKSNTAILDIQEEVPISRYRYKDIKEGFLKFIGDRIC"
     gene            complement(166029..166181)
                     /locus_tag="KRN00_000131"
     CDS             complement(166029..166181)
                     /locus_tag="KRN00_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826028.1"
                     /translation="MKNLNKNKILGEVIITITACDDEKEIQIVIKNQVDNILKNKNKE
                     YRIKKI"
     gene            complement(166782..>167311)
                     /locus_tag="KRN00_000132"
     CDS             complement(166782..>167311)
                     /locus_tag="KRN00_000132"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826029.1"
                     /translation="HSYEILIRKLVYNLLPKCKKINSKIIEREIKNNLVIDCSNILKK
                     YTNKIIINAHKVYINNEKIITLSNEIDLIAVVTKKLFIIECKDIYYKFTPYGFKCDIN
                     KTYSFISKMEKKYKSVLENKQNLEIKFGCEIEEIQPIIVFKTYNMAINSKLNNNRIKI
                     INFNGLEKLIRDTKN"
BASE COUNT        54848 a        29298 c        17861 g        65304 t
ORIGIN      
        1 tacatatttg attattttca tttgctgctt aaaatcaatt ttaagttttc ttcctataat
       61 aaacttcctc tttgtggtct catgttagtc tctaaattta aaattttaca aaaaattttc
      121 ataaaataaa attatattga ttgtatctaa acaaataggg caataaaata attaagtata
      181 gttacttacc tttcaagcaa tattagtttt atgttagaat tttattatat tgatttacag
      241 gaggtttgca tttgaataat attaattcac ttaaagtaat aaaattatct cttggatgtt
      301 ctcttgctat atttattgct tggctattaa aattagaata ttcaatggtt gctggagtta
      361 tagtactact tacagtaaag gacactaaaa gagaaactct taaaggctcc attggaaaga
      421 tttatggttt tcttttatgt actatttttt catatttatg ttttaatatt ttaggatata
      481 atttgacttc attttcaata tttatattta taattatacc actttgtttt ttgttaaata
      541 ttcaagatgt tattgctatg tgtgtagtca tagcatccca ttactacctt caaggagaaa
      601 cttctatcaa atggatttta aatgaagctg gaatatttgc agtaggaact ggaataggtg
      661 tcttaataaa tatgtatatt ccaacaaata tacataaaat ccatgaagtt caaaaaaagt
      721 tacaggaaga agtgagtatt gtacttatag acattgcaga tattattgta aatcctaaaa
      781 aagaaaatgg atatagtaga gatttatata cattaaattc acttattgac agcagtattt
      841 ctgaaactta cgataatatt aataatactt tattaagtga tactagattc ttcttagagc
      901 atatggatat tataaaaagc caacgggata tcttagaaaa tttgtatagt tatgtatctc
      961 aactaaattc tacaccacca caagctcata ttctatctgc ttttatacat aagataggtt
     1021 atactgaatt tgaagctgaa acaggcaatc ttcttcttga agaattaaag agactaatgc
     1081 ttagtatgaa aaaccagcct ctgcctgttg acagaacaga gtttgaaaat agagctattt
     1141 tattcctatg cttgactgag ttaaaacagt ttttagttaa tcgtaaacat gctcagatgc
     1201 ttagagataa taatttttat aaataaaaag gggagaaatc tagcagttga cctgactaca
     1261 aaatatcaga tataatatta aatgcgcccc tagtaagagg gcgcaatgtt tataacttat
     1321 tctactgtca tgattaaatc attattcata tcgaacatac attatttgac caagtccaat
     1381 attagctttt tcatcagtga tttctatttt aatagtcaca tcattttttt tacagtactt
     1441 cgctaattct gcaccagaac gatttttacc actaaaatct aaagaaaatg gcttatcata
     1501 tttaaaagga tattcaacag gtttaccctc tggtgctaat gcaaacatcc catatggtgt
     1561 gttcataaat cctattacag caatcgtaag atttgatggg tctaaatttg attcactacc
     1621 tgtaaatgta attgtattta ctgatgaatt aactacacta catctaacac cttcatacat
     1681 tacatgtttt tcatttatat cttctccttt ttttccaaaa tttccaacag cctttgcccc
     1741 ttcttgatgt ggtaacatag tgtgcttccc aggtggtgct ggtttctgtg tctgttctgg
     1801 ttttaccgtc tgtactattg caccaacttt tggatatgct gtcttatcaa atggtaatgg
     1861 gtggctaaga ctcttgtata tgatatcctt tcctgctgat ttattagcat caatatctac
     1921 atgatacaaa cgcccatcac caaaacggat aagattccac tggtggtcat ttgatgtgct
     1981 gtgtacataa taagattcaa ttcccatagc atcacacaaa gctttcatgc tcctagccat
     2041 tcctgaacat gcaccttttt tagtgaccaa tgtataggca gtatttgctc cctctactgc
     2101 attccagtca acatatgttg tgttattttt aatgtgattg taggcaacta aaatcttagc
     2161 atctgtagtc atattctttg tgattttctt gttcataaaa tctgctgttg cttgtgctac
     2221 tgagtttagt tgggcttgtg acagctttgg accatatacg ctattggttc cagtgacata
     2281 gctttttggt gtttttgctg ttacctcttt ggctgtcata ccataaactg tcatactcat
     2341 acctgagatt aaaactattg ttgtaatcaa taacttggta gctaacttcc taattttctt
     2401 catacttaat attctccttt ataaaacatt gttacttcct attctctacc attaataaaa
     2461 ttaatttagg atttaaaaag gtggattgtc aacatgtata tttctccatt catacattcg
     2521 tgaaatattt aaatttcatg gaaaatctaa tagatatttt ctagataatt tgtatacaat
     2581 acaactcgca aatcagggtg tttgctgtta gtttgagaaa atgatgatga ttaatacatt
     2641 cggaatcttt gacctataat aaataccatt gtcttcaatc attaataatg gtaagagtaa
     2701 agagaattat caataataca gttaaaatca actttgtata catttcatac attctctccc
     2761 aacaacatta tacttcttat aatttgtata ttcaatacgt tttctgggaa aatataggat
     2821 atatctataa aaatataaaa aaggagttga acttaaaatt tgattaaaaa aaatcaattt
     2881 taagacaact catttgtatt ataaaaatgc tatatattat tattaagtaa gtcaatattt
     2941 tagatattta tctatttctt attgacttac gcttatagtc taacttattt gtttagttga
     3001 tatataacct agttttaagc attattaata tttaaataat caagtatcct ttttgtttct
     3061 tgtagtttct gttctgcctc atttaagttt tcttgaatta tagaaatata tattatatct
     3121 atcaacgtaa gcattgctat tcttgaagaa atagctcctt ctctaagcct tttttctata
     3181 tttggtacta ctagctttaa atcactaatc ttactaagat gattgtcact atatttagtt
     3241 atacaaatga ccttacatcc ttttaatttt gcattttcta tagactttat tacttctttt
     3301 gattctccag agtaagatat tgctatagct atatcttctt tatctacatt tgaagatacc
     3361 ataagttgtg tatgactatc taaagaggta aatgcctgtt tatttatcct taaaagtttc
     3421 atctgtaaat ctagtgcaac taaagccgaa ccacctactc caaatatata tacattttta
     3481 gcctttatta tctgttcaac tgcttctttt attatatctt tttcattcaa caaccttgtt
     3541 tggttgatag tctctatgtt tttgtttgta attttgttta taacactatc tatattacaa
     3601 tcatagtttt catctacata tgtgtattca ttttctttgc ccatcaaatc tttagctatc
     3661 tcaattttta aatccccaaa acccgaatat cccatttttc tagaaaacct aactatactt
     3721 gctgtacttg tttttgagtt tgacgccaat tctgatacag aaagcttact tatagcctct
     3781 gtattattaa gtatgtaatc agctattttt ttatctactt ccgttaaatc ttcatatatc
     3841 tgttttaatt ttaaaatgca actcatactc tatcacctct acctatttac tataatattt
     3901 cttcttagca agtaaacatg ctcctaaatc tggagtcaac actggtctca ctataccaaa
     3961 tctcgtttta ttcaaatatt ttttaagtgg ctctaatatt aaatctcctg acttaaacac
     4021 tccacctgaa taagatacct ttatctttgt accttgttca aaatgatgct ctaatcctat
     4081 tataagccta cttaattcat aagctgcatc atcaaatatt ttactagcag tattatcacc
     4141 ttcaataact gcttttaaac atatcgtagc aaactttgct atttctattc tatctccttg
     4201 tatttcatca tttacatatt ttattatgtc ataatcattc tctatattaa gatgtctttt
     4261 tattaaatca tataattttg tttttgaaca ccttccatca gactgcattg tgaacatttt
     4321 taaggtagcc attcctatat aatacgctga accttcatct cctaatacat agccccatcc
     4381 tccacatctg tgaagattcc catctttatc taaagcctgt gctattgaac cagtacctgc
     4441 aattatattt ataccttttt ccccatttaa agaacctgct aatgctattt ctacatcatt
     4501 acctagagta taatttatat gactatatgc attttttgtt gctacttcta atgcatacaa
     4561 tacttctttt atttttccat atccagcaag tccaacaaat gcatacgtta tttcttctac
     4621 atttatctta gcatctttac aaacttcttc caacccagtt attaataatt tcgttagatt
     4681 atcaaatcct atttgattat aatgacaagt tcctttggtt atggttccta ctatatttaa
     4741 ttcttcatct actaatgtaa atgttgtttt cgttcctcca ccatctacac ctaaaaaata
     4801 catactatcc tcctacaata tctttaataa ttctttcaat acttaatatc taaaaataac
     4861 cttccaatgc tgttttttta atattgaaag gttatcagta ctattattta ttttacaatt
     4921 tttctattga ttttaaagct tcacttatat aaccttcttg tctatctagg atactctttg
     4981 cactatcctt atctaaacca ctttttatca taaatatagc caatttaacg ctattatctg
     5041 cttcttctaa gaatttttct gcaacatcat attttacatt tgtagctatc attattattc
     5101 tttttgctct ttcaaccaac ttttcatttg atgtcttaac atctaccatc aagtttgagt
     5161 atacttttcc catcttaacc atagaagctg ttgttaacat attacatacc attttttgag
     5221 ctgtaccact tttcattcta gttgaaccca ttattacttc tgcccctact ataatgttta
     5281 ttggtaaatc cgctttttta ctcatttcac tattcggatt catagttatt gatagtactg
     5341 cacaccccaa ttccttagca tactccattg cacctataac ataaggagtc cttcctgatg
     5401 cagctatacc acatataaca tccttagatg taactcctct atctattata tcttgctttc
     5461 caagttcttt atcatcttca gcaccttcta ttgctttaaa tattgcttga tttccaccag
     5521 ctattatagc ttgaacaagc tcaaaatcca ctccgtaagt tggaggacat tctgtggcat
     5581 ctagtattcc tatcctacca ctggtacctg ctcctatata gaataatcta cctccctgct
     5641 tcattctatc tactattata ttaacagctt ttgctatact ctccttttgt tcttcaacag
     5701 cataggctac agttttatct tcgttattta ttaattctat tatgcctaat gtatcttctt
     5761 tatctatttg caatgtattc ttatttctac cttctgtaac taaattttct aaagttttta
     5821 ttaacatatc atttcctcat tttcttaata ttaaattttt aaacacattt taattccaac
     5881 tttcataatt atatttttat aataaattaa tattttcata ataaattatt ttgttgaggg
     5941 tttaaaatta aacttttgcc atggtttaat ataatctaat ataaataatt cttcttttct
     6001 tatatatcct actacattcg atttaccact gtttttcata tcagtcaagg ctatttgtaa
     6061 ctcccctgca taatgaccat attcactact ttcaattact atatctcctc tttttattat
     6121 tttaggagta ttaaatagtt caaatttgta tcctttatat ttaacacgag attgagtaga
     6181 ccttatcaga ctgtcagata tgtcccctct attaaaatgt atttcttcaa agagtatctt
     6241 cttctcaact tctcgtatat tttcctctat tgctacatca aatgtaacca tatcttttct
     6301 catagaacct aataccttta gctcctcata tgttggataa caatttgata ttattatatc
     6361 atttatatta ttcatagcta ttatatgctt tacttgaata tctataggta gatttctgtg
     6421 catctcaatt gttggaagcc catcagttac aggccatggt ccaaatgtag tttcattttg
     6481 acttgttaca aaaactgctg ttcttaatcc atacttatta aatctttctg tacattttat
     6541 aaagtgttct aaatttaatc cactatatct atgtggataa aagttatgac atcctgtcaa
     6601 gttttcttta tttggttggt agtccattat tgtatctata taattagtat tattactcat
     6661 attgatttct attttaagat tttgaggatt aaaagtcatt aatgcctctt cagaacctgt
     6721 aaatcctata tcaagcctta ttccgtctgc cttcgtcttt ttaaaaaaat tcaaatcttt
     6781 gtagcttatt tctaattcac caaatactct gggatttaca tcaagtatta cctcaaaacc
     6841 tttaaactta gcgtattcat ttatactttt aaatttttta attatatttt ctttagtatc
     6901 tttaactgat aataaacatg aaaatatacg tgtaaatcca ttttcagcag ctttatctat
     6961 ataatcatat atttccttag atgttgtttt ttctggataa attgatattc ctaatcttcc
     7021 catctgtgtc atctccttat atcctatatg tgtttaaatt tatttcgaat tacacgaaac
     7081 ttttttaaaa atttggtgaa aaaaagtttc atatatattt ataaaaaaag aaaagtttac
     7141 cttttctttt tttataaaca atcaacaaaa tatcttcgtt acttatttca taactgttat
     7201 actttgaaat ttatactaat ctaatatagt ttttaatttc caatatagtt tctaattaat
     7261 aagcttcttg ctcttcaact ttttcttcat gaagcaatct cttatcgtac atcttgacaa
     7321 atggatagta aattattatt gatatagcta tacataataa gttaagaact gaagctctcc
     7381 aatctccacc agtggctaaa tatgccccta ctggtcctgg taatgtccaa ggagcagtaa
     7441 ctactactct ggatactaaa ttagcactca tagcaaacca tgaaactgtt gccattacta
     7501 ttggtgctac aacaaatggt attattaata ttgggtttaa tactattggt gctccaaata
     7561 ttattggttc atttatattg aatattgctg gtattacagt tgcttttcct aaagactttc
     7621 cataagctga ttttgctcta aatgcaagaa gtaaagctaa gcctattgta gctccagaac
     7681 ctccaatcca tataaaccat tgaaaaaagg gttcagcagc aatacctgga actgcttgac
     7741 ccgcagcata tgaagctgta ttagcatcta ataattgtat ccataaaggt cttgccaatg
     7801 aacctattat tgatacacca tgtattccaa atgaccaaaa aaacgttatt aaaaatatta
     7861 gtataattac tgatggtaat gtgtcagtgg ctgaaactaa tggagttact aatttagcta
     7921 tgaagccatg ccaatcaaac cctaggaaat aagtaacaat agccattaaa attattatta
     7981 atgcggctgg tgtcagagct tcaaaagacc ttgtgactga tgctggaact gcttctggca
     8041 tggttatctt gaatttagat ttgtcagtaa atctataaat ctcaacacct attatagatg
     8101 ttacaatagc aacaaacatt gaacctccac caagattagc cattggcatt tgccatcctt
     8161 gaggaattga attataccaa gctaaaagtt ctggactctt ttcaactatc tttaataaat
     8221 caggggtaag accctctatt gcagtaggaa ctattgtcaa aaggaatgta gctgtagcta
     8281 ataaacctcc tgtcaatcca tctaacttat atgactttgc caaactataa cctatgccaa
     8341 atgtagaata tactgatata ataaaaaatg tcattctata tggtagtaat attgtaactg
     8401 cattttcctt tagatactga gttacccccc atgaatctgg taatggagga aatgctaata
     8461 tcaagaaaaa tgacccaact attataagtg gtaatgaagc tacgattcca tctcttacag
     8521 ctcttaagtg acgttgttct gccaatctgg ccatagaagt tgataattta gtgtctaaaa
     8581 attctgtaaa tttatctagc atcttttctc tccttaatta atatttattt ttattatcat
     8641 taaaattttt ataaaatcaa ctttcttcta atctaacaac actgcaacta ctatttactc
     8701 aacagttctt gaacttgttt taataacttt ggtcctccta atggactata agcttgtgct
     8761 tgtattaatg cacatggtac actaacctca tcagcaaaag cttttaaata gtcaaatcta
     8821 tgtctgactt gtggagctac catagcaata tcccatccat ttttaacttc attctcaaac
     8881 tcttgagtac caacagccaa aacatctata tctattccat tttttgctcc ttctttttgt
     8941 aatgcattaa ctgctatagc acttgacatc cctgatgaac aaacaaataa tactctcata
     9001 ttgattcccc ctgttttttt atttcttttc aatcattata gcatgtattt ttgattacag
     9061 gaatacgttt gtatatattt tttcatattt tacattttaa attgtaattt tatttcatac
     9121 atttatatct tgctttaatt gctttattta tctaatcatt cttttgtcta aaattacaca
     9181 ctacttaaaa tactcatctc ttttcttaaa aaagaaaaaa gactatctta ttattaacat
     9241 aaaatagtct caatactttt ttaaatatgt attcctttat atatccagaa gtaacctatt
     9301 attgcaaatg ataaagcaaa taaaatatac agtctaaaaa atcccaaaga aaaacctctc
     9361 ttagtttcaa caaagtatct tgtatatgca actgcaaaag atgtaattaa tgaatttcct
     9421 ataacaactc caaatctatt atctattcca aatatagata ataacaaagg aaaaactaca
     9481 gtacttacaa gagatgaaac tattagtatt aatccacttt taaaacttat agttggaata
     9541 ttataatctg ttctttgatt tttctccatt tctttcttag tatttttatt actttttgta
     9601 ctttttgcat ttttataatt attatttttc tttcttttct tttttttatt attagacatg
     9661 tcatttacct ccaaaaggtt taggtgttat attccctaaa ataactttat ttttagcccc
     9721 tgttgcagat attacattag aaaaagaatt atttaatgtt tcattgccca agattacaaa
     9781 tgccaaagcc tcctttgcat cagaagaata cccatattca tcttgagtta atacttcaac
     9841 ctctaataat aactctttta tatatcctat taaagttaga ttatgagctc ctccacctcc
     9901 aattaataaa gtatctacat taacctttgg aagtatgaag tttttataat tataatatat
     9961 agcttttgcc gtaaacatag ttactgttgc tatcaaatca tatttatcta catgtttata
    10021 tttgttaagc atgttatcca aataaacttg tccaaatacc tctcttccag tgcttttagg
    10081 tggcgcttga ctaagatact tatgactcat caaatctttt aacatttctt cattaatttt
    10141 accttttgat gcaaagtatc catttttatc atactttcta ttaaataatc tttgacatac
    10201 tccatctatt atcatatttc ctggtcctgt atcaaatgca aatacatcat ctatgttaca
    10261 tgatttaggt attatagtaa tatttcctat tccaccaata ttttgaagtg ctaaattttt
    10321 attgttatca ctatataata aaaattcact atatggtact aatggagcac cttctccacc
    10381 tgctgctata tccattactc taaaattaga tattaccttt gtatttgttt catatgctat
    10441 aactgctggt tcacctattt gaagcgttga agatacaaaa ttattataac ttcttggtat
    10501 atgaaagatt gtttgaccat gagatgcgat aaaatccaaa tttgctatat gaaagtttgc
    10561 tttatgacac actgatttta cagctttact aaataaatat ccaagcttaa aatttaagct
    10621 acagattaaa tcaacactcg attcctcttc tatacagcac tttcttattt cgtcttttat
    10681 atctttagga atttctagag ttataaattc tatttgctta actttagtat ttctaccatt
    10741 cccactaatt tcagctagta ctgcatcaac tccatctaag gaagttcctg acattaaacc
    10801 tacactatac atagttatca tccttttaag tttatagtta ttcctcccca aatcaaggta
    10861 ttaagtttaa taattttaga attaatctta tttcatcttt aattacgata atttactctt
    10921 atgaaattaa ttgagttaat cttatacacg ttttttacct tagctaaatc ttacattaat
    10981 ttattttcag tgtcaatgta atgccatgta attttttttc acaaacaaaa catattctct
    11041 ctccaaaaac catattaaaa tagttactac aaataaaaaa cataccaggt acatatctga
    11101 tatgtttttc atatataata attattattt tataatatag atagagcatc atttaaggca
    11161 ctaattaaat cttcactatt ttcaagaact aaatttattc ttattgtata tgtcgatttg
    11221 tatatgatga tagattttat agtctaataa cctaactatc taggcttaaa taatctgata
    11281 tatcataaaa atagatatta aaaattgtat atgaaccatt ttccgaacat acctcaatct
    11341 catgccctaa actatctatc attttcttta caaaatacat ccccattcca gtagacttat
    11401 acaattgatt tcttccattt ttccccgtaa atcccttgtc aaaaacccta gatatatctt
    11461 cctcatttat acctatacca aaatctttta tagataatac cactccattt tctaactttt
    11521 ttgaattaaa ttcaatctta ccaacttcct ttgaatactt tatagcatta ttaataattt
    11581 ggtctaaaac atatgacatg catttagaat ctgtgtaaac atcattttct aattcattca
    11641 aactaacttc tacattattt tttataagca aaaatgaatt attttttata gacattttta
    11701 ccaatttttc taaattaaat ttatttataa atacatcttc aaacatagtg ttgcttctac
    11761 tactatacaa aatagagttt actaaaaaat ttatctttgc aacctgattc ttaatatcca
    11821 aactatcttc tatgctactt aacctatctg taattatact taaagaagat attggaattt
    11881 ttatttcatg aacccattta gctatgtact catccaattc ttttaatgat tgtttataag
    11941 tctctatgtc actattattt tttattttta agttttctat aatatctttt attagatttt
    12001 cttcaaaaga ttgtccatca actaaataac tgtctatttc accactattt tctatacaat
    12061 tatataaatt tgtgtaacta tttctaaaat ttatataatc tataacaaaa aataccatta
    12121 ttataaacag cactaaaaaa tctaaatata ttaactctga atatttattt ttaaaaatat
    12181 ctatagcaaa taagtagata tttattatac taactacaac taaaggtaga gcaatatact
    12241 tagacctacc tttcaaatat tttactagca ttgtattata tatcctatcc ccttcttagt
    12301 ttttataaaa tcatcaaaac ctagttcttt aactttactt ctcaatctat tcatatttac
    12361 agtaagtgca ttgtctgtca caaactcatc attatcccat agagtcatca taagactttc
    12421 ccttgataca accctattct tattttttaa taataatgtt aaaattttta tttcgttttt
    12481 agtcaactct atacttttat ccttatactt atgttttata atccctttcc ccacatcaaa
    12541 catcaaatct tcacaataca aaatactatt agaatcacta taattataga ctcttcttat
    12601 tataccattt attttggtaa ccaatatttc tatagaaaat ggtttggtaa tgtaatcatc
    12661 tgctccatta tttataccca ttattaaatc catatcagaa tctcttgatg ataaaaatat
    12721 taatggtaca tttgaaatag ctcttatttt ttcgcaccag taaaatccat tatataatgg
    12781 taaatttaca tctaaaagta ctacatctgg ttttttatct ataaattcat ctaatactac
    12841 ctcaaaatca tcaattaatt ctactttaaa tccccatttt tcaagtgcta atgcaatctc
    12901 ttttgataaa tcaatatcgt cctctactaa taaaattcta tacatttgta tattctccat
    12961 tatcctaata tttcactatg ctatgaatta ttaatatcat aacatatttt atatgaattt
    13021 attacccaaa ttatttagtt aatcaacaag gagactctta ttacaagaat ctcctttctc
    13081 tttattaata tatcaactaa tttttataca ctacactctt aaacttatta acagatactg
    13141 ctccatatat tatgaatatt atcaaacata tcactaaact tagtatatat ataccaaata
    13201 aatcggtcat caataaatct cctgctaatc tcaatgcaaa ataactagat atagttgcac
    13261 ttaacattgg caaagtataa aaaatagcta cttctttaag tatagctcta tttatatctt
    13321 tttctgtagt acctattttt aacaaaatct tatatttctc tttatcttca tatgcatcac
    13381 tatatatttt catatatatt atacttccag ctacaattgc aaagactaag aataaaaaca
    13441 caagcactac atatgcaaac ttcatccatt gactctcacc ttgagcttta tatccatttt
    13501 gaatatacac attttttaaa cttaaattct tttcaatatt gttgaacatt acttgactat
    13561 tttcttcttg aaataccttt gcaccataaa aatacacttg ttgaccctta tctcttagtt
    13621 taaaatatgt atcatcattt accactataa tactttgatt aagtcctgtc cctagtactg
    13681 gaacttttac ttctcccctt gaaatattat ataactgacc atcaagtttt atcttggctt
    13741 cttttgtagc tattgatgct atcgtttgag ggctttttaa ctctattaca ttatttccac
    13801 taactaatct ttcaccatac tcttttaatt ctttatcatt gccattcact ttaagagtat
    13861 tacaaaaatc actatatttc attatagtat ctgttgtatc ataagcttct tttatatctg
    13921 ttttctttaa aattgttagt tctggattta ctgagtactt tatcttatta gtatctttta
    13981 ttatattctc tatttgtttt ttattcactt catctttatc cattgaaact atgctaatag
    14041 tgtacacatt tctttgttct tgggcattct tatgtatacg cttcatcgca actgaagcac
    14101 caagagttga tattgttgta gttataatta tagctattat agcataagtt ttatagtttt
    14161 tatttaatcg gtagtttata ttgtttattg caattatatt atttccatta aataatattt
    14221 ttttattttt gattataata tcaaatataa caggcataac tgatttgaat aatccataag
    14281 tacctactat tattatacct ataacaggta gtacactagt tatatctcca gttcttatat
    14341 tggtagaaag atagtagcca tatcctatta ctataattga tactatagct aatatatata
    14401 tacctattcc tacctttggt attttttctt gttttttaga tatattgatt agatttatta
    14461 cactacttct acatattgtt ataaaacctt ttacagccat tattataaat atagaaataa
    14521 agattaaagt agcatatagt atagcttcta tactaagtcc attagatacc tttatattaa
    14581 atccagataa ctttattatc actacttgaa aaaatctaga tgttattatc cctataatta
    14641 ttcctgttat acaagaactt attcctataa gcatattttc tacaaaatat atttttccta
    14701 tagtatataa atctaatccc ataaaagaca atattccaat ttctttagac ctattcttaa
    14761 aaaatatatt tgttgcatac catataaaga aaaataaaaa tactgatagt atcattatta
    14821 cagctactaa cactgatagt gtaaattttt tattttcatc ttgtaacaca tttatagcat
    14881 caccatatct taataattca aaattagtta gcacaactac tgaaaaaacc atagatataa
    14941 aaaatgctag ataagttctt atgttactct taaaattatt ataagcaatt ccaagtatac
    15001 tcacttacat ctcacctccc atagaggcta gcatatccat aatttttcca taaaattctt
    15061 ttctactatt tcctttgttt aatttacact ttatatttcc atcatttatc atatatactt
    15121 catttgaata acttgctgtt agagggtcat gtgtaatcat tataatagta gcgttatttt
    15181 ctctgtttat tttttctaat gattctaaaa gttcatatgc tgatttagag tctaaagcac
    15241 cagttggctc atcagcaaat atgactgttg gatttgtaat taatgaccta gctgctgcgc
    15301 ctctttgttt ttgtcctcct gataactgat atggatattt atctaaatga ttttctaatc
    15361 caaatttttt agctatagaa aataccttag cttctatctc cttacttttc ttttttccta
    15421 atgctagagg aagtgctata ttgtccatta gtttcatatt atctaataga ttatagtctt
    15481 gaaatataaa ccctattttt tctcttctta attttgatag ttcattattt tttacttttg
    15541 atatattaat tccatctagt attatttctc ctgaagtttg tttgtcaagt gtagacatta
    15601 aatttagcaa tgttgtcttt cctgcaccag atggacccat tattgatata aaatcacctt
    15661 cattgactgt aagagatata ttttttaaca catttgtttt aaatcctttt attccataat
    15721 cttttgatat attttttatt tttaatattt ctttcataat aatagcctcc agttgctaat
    15781 tttttaatat atatttattt taaaggtttt atataaataa atccttaagt aaatattaca
    15841 ttttaactgt tagcattaca cttttgtaac atatggaaga ctattataat tatagtagaa
    15901 atatcttaaa ataaaaactt gcttcacttt tttgtataaa caaagaaaag aagctcctaa
    15961 gaagcctcta atctatacaa taattcttct ctataaaaaa ccaaaataca cattgattgt
    16021 ggcaaataca gatactataa acaagtgata ttactactat atattaaaac aattattcct
    16081 gaagataatt caataagact atcaagcaat aagctaagca tccaaaaaga cttaatacca
    16141 ttaatgtata attataccca atattaatgc tcaaaaaacc agcaacagtt ggaataatca
    16201 gagatgaacc tcccataaat atacttaaag ctattaattg gctactactt ctaagttttt
    16261 taggagaaac ttcaaatatt aatctttttg aagtaattaa aattaaagga gtagaaaaca
    16321 cttgaaaaac acacagtata ataatgatat ttgaatcatt tgttaaagca aataatagaa
    16381 actgaactgt tatcataata gcacttaatt ttaataagtt taaactgcta tattttttta
    16441 ataaataaga accagccaga tatgttggta tctctaacaa tgactgtaaa gaccacttta
    16501 aagatatctg agaatttgta gcatttaaag ctatcatttt atctattaca gtacagttat
    16561 ttgctaccac cattgagtat aataagaata aaatacatac tagtaagata tattttttat
    16621 cttttaataa ttcaataata tctttattag ttacatttat tttcttatta atcttttcaa
    16681 tatcaggtaa taatagtata tttataataa gtaatactac aattaaacca atcgctacag
    16741 ataatccaaa atatgagaat ctaagaatca agtaagatgc taccatactt ccaatagccc
    16801 atccaatcga cccaaaagtc ttaataaatg acaaataatt attaatatta tctccacaac
    16861 ctattatcca tgtatcatat aaactacagc aagtatttaa taatcctcct gataaagcaa
    16921 caagtaataa gtatattata aaagttgcag attcagtaga aaacataata actgatgcaa
    16981 ttccataaac tgataaacta attaaaacaa tttttttcat tgtttgatac ttatcagcta
    17041 atactccaaa taataattga aataatatat tggttattgc ataactcgat aatataattc
    17101 ctctttcaaa cgctgagtaa cccaattttg ataagaaagg tgtgaatttt gttgaagcaa
    17161 aggcaaaaat aatatatgag aaaaaataga atatgataaa tttaaattta atcgctttat
    17221 taatcataat caatcaaaat tgataacttt aataccacta tttccttcct gatttaagtt
    17281 tgaaagatga tattttaccg tattaggatt ctctacaata actaaaggaa tatataaagt
    17341 attttcaagt aacttattat caatttctac taacttttcc cccatattaa cttcttgacc
    17401 ttgtttaact tctaatttaa agttttcttt ttttgttgtt gcactatcca atccaatatg
    17461 aataagaatt tgaacatcat tttgcaattt aattcctata gcatggttag tttgagcaat
    17521 aaaacttatt actcctttag tcggtgattt aagaatattg tcctttgcta tcatagcaaa
    17581 tccatctccc attaccttag ttgaaaatac tttatcagga atttctccaa gattaattat
    17641 ttttccatca atgtaggaat taattgtaat tgcttctttt tttcttttaa agaacattat
    17701 agacactcct ctacataatt aactttattc taattatcat tacaaataac gatattaagc
    17761 atactgcaat tgaggaaaaa agagccttat agctctttcc ccattgtaat tctttaatac
    17821 tgcttatgat ttgtctaatt ccaacaaatt tataaatata ggtaaacatg ataacaatag
    17881 ttattgtgta aatttggaat atctgcccta ataagactaa atagaaagca atcatgtttt
    17941 cttttatctc tttattcttt tttatattgt aaataacata tgcactgtat actgcactaa
    18001 agttagagat taaatttaaa cttgcattaa catcattgtt taaaagttgt gaaaatgaaa
    18061 tatttgtaaa taatgatgtc aattctaaat acactatata taaaacaggt aatattagaa
    18121 aacaaaccat aaccactgaa agaaatatat tttcatcttt taatactgct gtgatatttt
    18181 ttattttatt tgttatcatg tttttgttct ccttatttaa aagttggcca gaaatcctta
    18241 ttagccacaa tcatttcatc taagatttct tttgctactt ttgcacttgg aacagtttta
    18301 ctcatagtaa acgactgcca taatttttga taattttttt ctatccatgc ttctacagct
    18361 aatttttcag aagcaacttg ttgttccatt aaaccttttt ggaaagttgg aattttacct
    18421 atagacatag gttcaaccat atcttttcca acaaggcaag gaatttcaac cattgcatca
    18481 tctgcaaaat tttcaatagc tccattatta ggaacaatca gtaaaaatct ttcctgagta
    18541 ttaaatgcta atgcacaagc taattcaaca ataaattgag aatgctcact tgcatcaaac
    18601 catgtatccc ttgctgtgcc attttttata attctttcac attcttcgaa tgtatccttt
    18661 tctcttctat ccataatttc atttgctctt gtataatttg gattagcatg ttcaacagtt
    18721 tcatcagcca ttaaataata ttttaaataa gtattaggta atgtagtcgg ttctatttcc
    18781 aataaatcct ttgctgctct catagtttct aaccaactag attctttgtg ttgaccttga
    18841 ggtgtaaatt cctcatatcc ttttttagca caatattctt gtaatttagg cattaaatca
    18901 tttccttctt tgtccttaat acttgtccac cacccgaaat gattcaatcc ataatatcta
    18961 acatcaaagt ctttacgaga atttaaacct aaaactctag caaatatttc ctctaaacat
    19021 actggcatat cacaaatatt aataattctt gaatttggtc ttaatacacg acatgcttct
    19081 gcaactatag ctgctggatt tgaataatta agcatccaag catttggaga atatttttcc
    19141 atataatcaa tcatttcgat tattggacct attgttctta atccataggc aattccacct
    19201 gccccacaag tttcttgacc aacaacccca tattttagtg gaattttttc atcttgttca
    19261 cgtaaagcat ataaaccaac acgaatttgt gccattacaa aatcaatatc agtaaatgct
    19321 tcttctggat ttgttgtata actaaattta atttctggat ttttctctct aacaattatt
    19381 gcacatgctt cagcaacttt tctttgtctc tcatcattat tatcatataa tttaattgat
    19441 tcaataggaa atttagcaac actttcaatt aacattgtta caattccagc agtataagta
    19501 ctacccccac cagcaattag tatcctctgt ctttttcttt ccatctttcc ttctccttta
    19561 taataaattt tcaaattctt ctcttacact tggtactgaa agcccaataa taatctgaat
    19621 agcttttcca ttatgcacta aaccatgtgc acctactgcc ttaaaatctt cttctttaga
    19681 aataattgag tcatctttca aggttaatct caatctcgta gcacagtttg taacatctac
    19741 aacattttct gctccaccaa ctaattttat gtattcagat gcttgttgag aggctttact
    19801 caatttattt cctttttcat ctttagtttc taaatattca tttttagtat atagttttgt
    19861 ttcttcacta tcttcttctc taccaggagt tttcatatca aacttcttaa ttaagaaagt
    19921 aaatacaaag aaccagataa atgaaaatat aatccctaca acaacttgaa caacatatac
    19981 cttccagtga tacattccaa gaggaagcca atttaataca acccagttaa taattcctcc
    20041 accaaaatca ccaacaactc ctagggcaaa cgaaatcgtt tgcaagcatg catctaaaaa
    20101 tgcatgtact aggaataaaa gtggtgctac aaataaaaat gtaaattcta acggctcagt
    20161 aattccagtt aatactgcag taagagtagc aggaatcatt aaacctaata cttttttctt
    20221 tttttctggc tttgcagtta catagaaagc accaaataca cctaatgaac caaacacctt
    20281 cgataatccg gataatgaaa atccgattgg atacatttcc tttagagtct tagctgaagt
    20341 ttgaaagtcc tgaatatgag tagcccaata tactgatgta ccacctggaa caacaacact
    20401 atcataacaa attggtgcat atacaaaatg atgtaatcca gttggtatta aaatcttttg
    20461 taagaatgca taacaccaaa ctcctatatt tccactattt ataaaaaacg tttgcaaatg
    20521 tctaataaca ttttgaatat gaggccaaat aaaacaagtt aataatgcaa ctggtatcat
    20581 aacaaagaaa caaattgcaa ctacaagtga tgagcctcta aataatccaa taaaatctgg
    20641 cagttcttta tcataaaatc tattatgaat ataaatgaca atacctgata ttaacaaagc
    20701 accaaccata ccagtatcta atgttttaat accagcaatg cttacaagtc cacttccagc
    20761 acttatttca gctgcgaaat caactccaaa gctttttccc caaaaactta acatagaacc
    20821 tacaaaataa ttaaaagtca aatacgttgc taaagcctcc atacaagctc ttgcttgttg
    20881 cttttttgca agtgctattg gtaaagaaat agcaaataat aatggtaatt gattaaatac
    20941 catccaagct ccactagata ttacacccca aaattggtac caaatatttt ctggtgtagc
    21001 aagtgaaccc ataattgact gattttgaaa tacaattgag aatccaacca ttatcccagc
    21061 aaaagcaaat aatagtgttg gtgtaaacat tgcccctcca aaacgctgta ttttcttcat
    21121 catataaatt actcccctcc tcatattttt agtttatctt tggccttaga tatctattat
    21181 tttaacaggt taataaatat atacaatctt tagagtacat tcggagctta ttcacagtca
    21241 aataagtttt tgcacttttt tatgttcaaa ttctcataaa aaaaaagaat gactacaatt
    21301 tgcaatcaat cccttctgta atcattctat gccttttata aatactatat ttaataaata
    21361 ataactcaat caatataaaa tataacattg tcaatttata actagggtgc atttgtaaaa
    21421 atgagatatt agtcgctgaa atataaattg attcatcact taaatcagtc aatgtattat
    21481 ttttaaactc tgtaattgaa attattttag ttcctattaa ttttaatctt ctagcaatat
    21541 taagtgtatt ctcattctca ccacttaggg atataataat cataacatca tttttactga
    21601 caatattgta aaaagaatca tcaaatgttc ttccctcaaa atcatatatt atttcttgac
    21661 atgataagaa cattctcttt atctgttttg caaccacatt ttgaatatca cctgaaccat
    21721 aagcgtatat tgttcttgat tcataaagaa gtttacacaa tgcatcataa tctttatttt
    21781 tttgatcttc aacatactta attattgaat tacatgcaat atcaaatgac tgattttcta
    21841 tgacatgaac cttttctgat tcccagctta ataatacttt aaactcactg aaacctttta
    21901 aatctaattt tttaacaaat cttgtaatag ttgcacgaga cacattacat ttcatagcaa
    21961 gttcatttat tgacatctta ctacaatgtt ttttatttgc agttatatat ttccatatta
    22021 ataaatctgt atcattcaat ttattataat ttaaaaaaat catttcttct aatctcataa
    22081 actattaccc cctttaatta aaaatcgtca taaatattat accaatattc aacattaaat
    22141 tacagcgtat tcttatattt actatttagc ccataaaatt gactataaaa aatactgcta
    22201 taattgatgt ttaaaaaaat gtagttttaa ttttattctt ttatctaata attaatattt
    22261 tcaagttcta gtgcttttct tatacaatta tcatctttaa aatcagcagt ccttttacaa
    22321 tcttttactt taaattctgg aatagtttta aattcctcat cacatattcc attcttattt
    22381 aaatacatac aacttgccat tctaactatt agaccactat tttttaaatt aaacaataca
    22441 gggtctatac accctccatc tccgccagta gtttcaccaa ctaaagtcgc aaatttattt
    22501 tctttacaaa acattgcaaa tgactctgat gatgaatata tttttctatc aacaagtaag
    22561 tatatattac ccttaaattt tgaatcatct gtagatttta tagtatagga agtatcttca
    22621 aaatcattaa aatcttttat aatttcttta ggtgcatttt cctttacact tgctggtaaa
    22681 ttttctacag gatttaattt tatatttctt gcatttgtat atttttttac tatttcatta
    22741 ttatttctat aaattctata accatttatt ttgacatcat tttttatgag tttagatacg
    22801 attccttgcc aataactatc acttccacct aaattacctc ttatatcaat aattaaagct
    22861 ttatgttttt ctaaagtgtc aatataatct ccaattattt ttaaatcatt atttatagag
    22921 ccattctttg atgacattga tggtaaatac atatatccaa tctgaccctt aataacatcc
    22981 tttaaaatta attctttttt tacaaaaata tcatctggca tttttatttt aagattcata
    23041 gagtcatatc tatccacaac ttttttatca ttaagaaaat cataccaatc attattagag
    23101 tatgatttct taaaaagttc atatcttttc ttattatcta ttacttctgt gtgtttatta
    23161 tttaaatcag ataatataga tgacagttct tctataaatt cttcatcatt ttcagtgttt
    23221 tttattcgtt ttgtatattc atccttattt gctaaccaat caatattatt aagcctctta
    23281 tttacaccta gatatggata tcctgtcttt acaacattat acacataatt aaagtcatcc
    23341 accttttcct cttcagacaa ctgattcttt tgagaataag tagaattacc taataatatt
    23401 ataaatgcta aaataattac taaaaataat actttctttt tcatgtaatt ctcatccact
    23461 ttcagatttt atattttaat acattgtatc attattttat tatcacctaa acagttaaaa
    23521 gaaattcttg aagatatatt ccactattat tctatttaaa aatttttatt tgtattttca
    23581 aaattatttc atgaaagtta taaaataaca attatattca aatatctatt ttactgctat
    23641 atcctgaagg taaattctta tcagtgatat actaaaaaag atatgctaaa aaatttatcc
    23701 attataatga cttaaattta gatactttac tgatttttat ttattagttg agaaagatat
    23761 tgataattaa aaatattgat aactatagaa atgattattt tttatagaaa ttttaaggat
    23821 ataaactaat tatacttaag tctatatcct taatttatca tgattatgag aatttttaca
    23881 aatacttatc tttgtccgtt ttagaataaa aacaagaaca tatcctgttg ttttattcaa
    23941 acatccaaat ttaattacta cacaattact tattagaaat tgtatctact tcatatatat
    24001 atctgttaag tatagcttct agcatttctt gtcttccaga cttattcttt ataactggca
    24061 tttgcagtgc ataagattct aactctttaa atccaacctt accttctact atatccttac
    24121 ctataccttc actaaaactt gcatatcttt ctttagtaaa gttttcaaat acctcatctt
    24181 ctaataattt atgagctatt aataatccct ttgcaaatgt atccattcct gcaatataag
    24241 ctaggaataa gtcttctacc tcaaaagatg ctcttcttac tttagagtca aagttaaatc
    24301 ctcctggtgc tattccacct tgctttaaca cttcatacat agcaagtgtt gcatcatata
    24361 tatttgttgg aaattggtct gtatcccaac ctaataatag gtctccttga tttgcatcta
    24421 tactacctaa aacattgttt attcttgcta tatttaattc atgttggaaa gtatgtcctg
    24481 caagtgttgc atggtttgct tctatattca ttttgaagta tttatccaga ttatactttc
    24541 ttaaaaatcc taaaacagta gcagtatcaa aatcgtattg atgtttagta ggctcttttg
    24601 gcttaggctc tattaagaat tggccagtga atcctatttc cttagcataa tctacagcca
    24661 tttgtaagaa tcttgcaaag ttatccattt caagttctgt attagtgtta agtaaagttt
    24721 cataaccttc tcttccaccc cagaatacaa aattttctcc tcctaagtac ttagttattt
    24781 ccatagcttt tttaacctga gctgctgcat atgcatatac atctgcatta catgttgtag
    24841 atgcaccatg aacaaatctt ggatttccaa acatattggc agttccccat aataacttta
    24901 tacctgtctt ttccatatta acttttatat actcaactat ttcatctaat atcttatttg
    24961 tctcttctaa atctcttcct tctggtgcta tatctctgtc atgaaaacag aaatactcaa
    25021 ttcccatctt agacataaat tcaaatcctg catcaacttt aatctttgct atctcaattg
    25081 ggtctgttat attattccaa ggtctctcta ctgtgcctac tccaaatggg tcattaccct
    25141 ctccacataa agtatgccaa tagctcattg caaatcttaa gtgttctttc atagtcttat
    25201 tacctaccac ttgttcagga ttgtagtatc taaatgctaa ttcattgtca gattttactc
    25261 cttcaaattt tatctgtcct attcctttaa atatttcact catttcatgt cctcctaata
    25321 ttttacacat ataatatatg tagtatgttt tcttaattta aaactatttt ctatctttat
    25381 ttttcttttt aagctaattt aattatttat ttttgcatta actacttcat ctaataactt
    25441 aaagtcatct ttcaaagatt tgtatattct tttatacaat ctatgatata tattgtatgt
    25501 atctacattt tcacttattg gttctaattt agttgaagtt tttattatag catcacatgc
    25561 tttttgtata ttttcatata ttccagctcc tactaatgca agaattgcaa ctccaagtgc
    25621 tggtccttca cttgaattta tagtatatac atcttgatta aacatatctg cttgcatctg
    25681 tctccatact ttactttttc cacctccacc tgaggctctt acttcattaa cgtctatatt
    25741 aagattctct attatatcca tacagtcttt aagactatat gaaacacctt ccattattga
    25801 ccttgcgatt tcttttttag aatggattgg agataatcca aagaacacac ctcttgcata
    25861 agggtcaaga tgaggggttc tttctcccat catatatggt aagtaaagca atccattaca
    25921 tcctgttggt acttgactta cttgattatt tataatctca tatacatctt cacctaaaga
    25981 atttgaaact tccacttcac tttgacagaa attatcttta aaccatttta atgacaagcc
    26041 agctccttga gtaactccca taacatgcca tgtatttggt attgcatgac agaaagtatg
    26101 aactctacct tctttatcaa tttttggctc ttttgtataa gcaaatacta cacctgatgt
    26161 acctatagta gatgaaacta ctccatcttt aactattcca tttcctatag ctcctgctgc
    26221 ttggtctcca gctcctccta ccactattgt tccttcttta agccctgtca aacttgctac
    26281 atctctagtc acataacctg taatctcttg tgattcataa actttaccta aaagattttt
    26341 atctatattt aacttttcta gtacttcatc gctccaatct ctttttctta tatcgagcaa
    26401 ctgcatacca cttgcatctg atacctctgt agcatattca cctgtcaatt tgtatcttat
    26461 ataatctttt ggaagaagta ttttattagt atttttatat atatctggtt cattgtttct
    26521 aacccataat atctttgatg ctgtaaatcc tgtaagtgct ggattagcag ttatttcaat
    26581 cagtctttct tcacctacta aatcagttat ctcctcacac tcttttactg ttcgttggtc
    26641 acaccatatt atagagtttc tcaatgtttt accttcattg tccagcataa ctagaccatg
    26701 catctgtcct gataatccaa ttccttttat acattcactg cttatatttg aactttgaac
    26761 tacttctctt atagattcga ctacagcttt ccaccaatca tttgcatcct gctctgccca
    26821 acctgatttc tcttgtataa gaggatattc atatgtacaa ctttttatag tatttcctag
    26881 tttatcaaat aaaactgttt tcgtacctga tgtaccaata tccacaccta atacatactc
    26941 caacttcatc cctccttgaa tgccacttca taactatcgt tttcctatcc taattttttt
    27001 atattttagg tatattttac ttgctttatt tttgttagta tattaaacta acttatgaac
    27061 taataataaa atatttaatt atctttgtca atgcaaaata accttttatt tttgtgtaaa
    27121 aagtattaca atattatttt aaggaggaat atcaaattgg ttactgataa atacactatt
    27181 cgagaaatga atgaaagatt ggtacttgaa caaattataa aaaatggtcc tatttctagg
    27241 gcaagtatag cttctactat aggattgaat aaagcaacta tatccgctat taccaaaaaa
    27301 cttattgatg aatctctagt tcatgaaata ggaattggaa atagtactca tagtggcgga
    27361 agaaaaccca tattattagt atttaataaa tgtgcaggga tttctttaag tatggacatt
    27421 ggatacgact atatattttc ttctctatct tacttagatg gaactattat aaattctaag
    27481 aaattaacag atatacaagt aagtaaagac aatgttatac aattgataga tgaaattata
    27541 aatagttata acatatccaa aatagacact ccttataagg taattggtct tactttggct
    27601 atacatggga ttacttgtga aaataaagta ttgtttactc catattacaa tcttaatgag
    27661 attgacttat atagcatcct tagcaaaaag tatgactttc ctattcacat agaaaatgaa
    27721 gcaaacttaa cagctttagc tgagaatact ttttcaactg tacataactc actacttagt
    27781 ctcagtattc acagtggatt tggttcaggc attataataa ataataaatt atatagtggc
    27841 agaaatggta tgagtggaga aattggtcac actatcatca tgcctaatgg taaactatgt
    27901 ccttgtggaa atcgtggctg tttagaacag tattgttcag aaaaaaaggt atttgaacag
    27961 ctttcttctt tagaaaatat tcctaaaata gattctgata tagtaaaaca actatattat
    28021 gaagataacc agaatgccaa aaaagttatt catgagtttt gtagttactt aacaatagct
    28081 ataaataatg ctattacaac ttatgctcct gaaataatat atttaaatag ccaaataatt
    28141 agtgatatcc ctgagatatt acagattaca aaagatatgt tagttagctc ttttaacaaa
    28201 ggaataaata tagaaatttc atcattaggg tctgaggcat ctctatatgg tggctctgcc
    28261 gtaaatatca agagcttttt gaatatacaa aatttaactt taattaatga aatataaggg
    28321 ttatgactat atacagccat aaccctttaa attatacatt ctaaaattag atttattata
    28381 tagtttatgc aagattagct atacttttta aaaattgtat atcaattaag tattaacata
    28441 agtatttcgt tttaaatatt aatataatct tcctactcat catcagataa taaacttgca
    28501 ttttgttcaa ccatagaaat attatcttta cctattttct ctaattttgc tgccaattcc
    28561 tttgtatcta aaaaagctga ttcaataacc atacctaaat ttagccctga aataatttta
    28621 attcgactgt cattattggc tactaataaa gcagcattgc atggagttcc acctagtaaa
    28681 tctgccatta taattatttc tgaactttcc ttgtacactt ctaaagcttt ttttaatttt
    28741 tctattgttc cttctattcc atcatcttgt ttcatattta cagtaggata atctatagaa
    28801 tcccctatta tcatttttgc agaatttaag acttcttcag ccatattgcc atgactcatc
    28861 aaaataatac tattcacttt aatacacctc tttaaatcta taagatgtct acaagataag
    28921 ttttcttatc atcaggcgtc attatagttg taatttcaat tccttcatct aaaagtcttt
    28981 taaatgcttc tttctcttct tcagtaacac tgatattagg tcttagaact gttgtatctt
    29041 ttctacttga catatttcct acatttatat tatgtatttt aaatcctgcc tctacaaatg
    29101 gaataaggtc cacaggagac ttaacaatta ataatacatt ttgtccttca tactttcctg
    29161 cagtaatatt ttttatagca gtctcttctg taattataga tgacgctata cctgcaggtg
    29221 tagccattct taaaacttgt ttttgaacag aattgttagc tactgcatca tttactacca
    29281 ttaatcttgt aacacccaat ttattactcc acatagttgc aacttgacca tggattaaac
    29341 ggtcatctat acgaatattt ttaatacctt tcatttccat atctaatatc atcctttcct
    29401 tattttaaaa tacctaatgc atataaaatt attgaaacaa ccattactcc taaaattaag
    29461 tatataggtt ttatattctt tttaagagcc caataaacaa tcacaactag aattgcagga
    29521 actaacccag gcataatttg gtctaatatt tcttgacctt tcattgtaaa atcaccttgt
    29581 tgaaagttca aagcaacatt agcttttaca actgaaggta ttaatgcacc tacaaccatt
    29641 aaacctaaaa tagatgtact ctcagttaaa atctttaaac ttttttcaat tgaagatatt
    29701 agcttagtac ctgatgtata accagcatta aatagtggta tacttaataa tttcaatgct
    29761 acactcacta caatccacag taagattcca aatggacttc catctatcgc catattagct
    29821 gctatagctc caaaaattgt ccacggaata acgacaaata aactatctcc taaacctgct
    29881 actggtccca tcaagcctgt tttaattgaa gcaacagcct cttcagtctc ttcacttgat
    29941 aactcctcca ttgctacatt aatacccaaa atataagggg caacccaagg attagtgtta
    30001 aaaaattgta aatgatttaa tacagcactt tgtaactttt ctggattatc tttgtatact
    30061 acttttaaaa aaggtagtac tgcataacag tatgccaagg cctgcatctt ctcataattt
    30121 gaagaaacag aactagtaaa aaaccagcgc cataagacac tttttttcac cttttcattt
    30181 gatttattta atgatacctt atcactcatc ttcgtccata cctcctacta cagtatattg
    30241 ttgttcttga ttttccaaat tctttttgta aattataagt gcaattgctc caccaattaa
    30301 agctacacct aataatggta ctttcatata tactgctaaa acaaaaccaa ttactaagta
    30361 actaaaatac tccttagcag gaagatatct aagtaataat cctatcccta ctgctggaag
    30421 tagtcctcca gctactgtta aaccacctgt taaccattca ggtgtatatt tcaaaatggt
    30481 attaattaaa gaaggtccaa atattacaga tagagcaact ggaatacctg ttgtagctgc
    30541 tgttaatagt actcctaaca tttgcatata ggttatattt ttataatttc cttttttagc
    30601 tccatcttct gctttatgaa ctagccatat accaatagta tttctaagaa catctaattg
    30661 taccatcaat aaagcaactg gaatacctat agagattcct acagatgctt cttgcttagt
    30721 cgtaatagtt ataaatgtgg ctactatact tgctgtttga taatcaggta ttgatgctcc
    30781 accaaagtta ctaataccta atgataatag ctgtaatgta cctccaatat ataaccctgt
    30841 atttatatct cctaagataa gaccagtaat aaaacctgct gttactggtt gatatgttcc
    30901 aaacattgtt gaattttttt catagtttat aaaaaatcca tatagtacga ttaataataa
    30961 ttgccataat tgtggctcca ttatgatttc acctctccca aaatattttt tagttcttta
    31021 aaattataac tggaatcttg ctttaggaaa ataggaattt cttccagtgg gcattcaact
    31081 tcataagttt tcccaccttc ataactaact ccactaaata tattttccca tgtatgtcct
    31141 tttggtaaat atacttttct acttctatct ttataattca ttattggagc taccaaaatt
    31201 tcatctccaa gcatatatgt attatccacc tcccaagttt tatcatcttc aggaaattca
    31261 taaaataaag ttctcataac tggtgttcca tcttcatgcg cttctttcat cagttttttt
    31321 aaataagttt ttaagctctc tctaattttt atgaattttg taagaattac ttcaacttct
    31381 tcaccataag accatatttc attaggagct ccagttacca ttgagcctcc acctttattt
    31441 gataatggtt tactatgagg caatctatct ccatgcattc tcaaaattgg tgaaaaagta
    31501 gcatattgga accatcttac cataagttct ctaaattctg ggtctttagg atttcctcca
    31561 tggaaacctc caatatcagt agtccaccat ggtatacctg ccagtcccat atttaaccct
    31621 gtatttactt gattattaaa agcttcaaaa ctagaatcaa tgtcaccaga ccatactaaa
    31681 gctccatact tttgagctcc tgcccaagct cctcttacaa gagttacaac agactctatg
    31741 tcattatgta aaccatcata aatcattttt aaataatcaa taggataaat attaccacaa
    31801 cttaaaacat ttcctttttt atatctatag ttatcaaaat catacacaga atagccaggt
    31861 tcagctacat ctaaccaata atagtcaatc ccaagttgtt tataattttt atctattcta
    31921 tcccaaacat attctcttgc attttcattt gtcatatcta caaagactgt atttccttga
    31981 atttgcattg tcattctaac accacgatta acattgacta aatagccatt ttctaaataa
    32041 tcattgtagt tttctgcatc actttgaact gtaggccata cagatactat tggttctact
    32101 gaatactctt ctttcaattt tttaactaat tctttaggat ttttccaata atctaagtca
    32161 aatttatatt caccttgctt aggccaatga aaatagtcaa ttgcaattga tgaaagctta
    32221 attcctcttt tagaatattc cttcacaaca tctaaaactt cttctgaagt tctatatctt
    32281 agtttacttt gccatagtcc taaaaggttt tcaggcatca taggaacagt tccagtaact
    32341 tgagagtaat ttttatttaa ctcttttggg ctttctccac aagtaatcca ataatctata
    32401 aaatttgtag aaaacatctt ccattctgtc atatttttag caaaagatac ttttccaatt
    32461 cccggattat tccataaaag tccataacct agactagaaa tataaaaagg aactgatatt
    32521 tgagaatttc tttgggctaa ctccaaaaca gtattcttta aatctaaaaa tttatgttga
    32581 tattgtccca ttccaaaaat cttttcagaa ggctcagatt caaatctagt agttacttca
    32641 aattctccac tatagcttgg tcgatattct cttgatttta actttagagt agagttaaag
    32701 tctttggtaa tctcaattgt ccctacatct tctccaccat catcatgttt tacagctctt
    32761 aatcgaatat attctttcaa taatatttca tttttatcat tataaaaagt aattctatct
    32821 ctatggtcta agacagcttt tatctttcca tttttaatga ttgcacttcc atcttcattt
    32881 ttattaattg taatatcatc tttatttaac ttaggttttt cgttaagagc atagttttca
    32941 tcaacaaaat tttggtctac aaacgaccta atacgtaaag agttttttcc ccatgcttct
    33001 attcgcaata gttcattgtc aaatcttttt tcaatatagt cttcagatat ttttatcacg
    33061 gctacctcct aaatcaatgg tataatattc tatctttgtg tagcttaagt taaataacgt
    33121 cgtttagtat cgttatttat aaattaggtt ttatatataa ttcatttgta cattaaacta
    33181 acttaccaat aatatacttt atttgacttt gtttgtcaat cgctttccgg attttagtaa
    33241 aattttctaa ttaagtaatg gaaagtaatt cttaatattt tttatttata ctttttaata
    33301 tctgtgataa tatttatata cattatatat tcattgaaaa tcaaaaaatt gttttttagg
    33361 agtctattat gaatacactt aaacatgaat cggtaaatat ccatgatgat ataggtgtaa
    33421 agctctatct atctattgat aatggaagtt ttacagttaa acactggcat tatagtcttg
    33481 aagttattct catacttaat ggaagcttta atctttttat agataatgaa agattaaatt
    33541 taaaggaaaa tgatttaata atattaaatc caaagcaaat tcattctgct atttgttctg
    33601 atggtaatga atctatagtt cttcaaattc cttataaatt tttagaagaa aacataccta
    33661 atataaatga gttacgtatt aattataagg aattgcttac tgatactgat aatactaatg
    33721 tgaataaatt aaaaaatact ttaaatgaat tatataagat atatagcaaa gagcctcaac
    33781 tatatatatt aaactcaaaa attttattat atgaattttt atatatttta tatgtgaatt
    33841 attcaatttc tatagattca atatcttata aaaatacaga taaatatttt gatagactaa
    33901 aaattataac tgattatgta aaagaaaatt acaaagaaca aatttctcta tctacagcaa
    33961 gtaaagttgt aaatttaaca cctcaatatt tatctagatt ttttaaaaca catatgggaa
    34021 taacgtttac ctcttatgta aataatataa gacttgaaaa tatgtatagt gaccttataa
    34081 atacagataa taatatatta gatattattc aaaacaatgg attttataat tataaacaat
    34141 ttatgaaatt atttaagaaa atatataatt gtacaccaag tcaaaaacga caacaaataa
    34201 ataaaactag aaaagatgtt gtctcaaaat atagataagt ctatttttcg ttattgagat
    34261 gattaaaata gacttgattt aatataaaaa agagtgtctc atgaactaaa aagttcactt
    34321 tgagacactc ctttatatat tatctacttc ttaattcatt tattacctct ctacattttt
    34381 cttcagttag tggatacatc tttataagta ctaacatagc tactgtaagt actactggta
    34441 taataccatt tatagaacga ataccgtaca aagcttgtga agtttgagaa gtatttgcaa
    34501 catatcctgt catagataat actacccctg gaactaatcc acctaaagcc ataccaaatt
    34561 taaagaagaa tcctattata gaataagtta taccttctct tctctttcct gtttttaatt
    34621 caccatattc aatagtatct ggaactaagc tccacattat tccagtgcta gaataagcta
    34681 taccatgaat tactctaaga atcataatta aagttatatg ttcttttccc aagaacatca
    34741 ttccaattgg aagagataaa gtaactacag taaaccaaaa tattatttct ttcttgtcaa
    34801 atttctttaa tagaagtgga gtaacagcat atccaactaa tacagcacct tttcctagta
    34861 tcatatatgt tggaattaag tcttctctac ctaatacata ttgaaagaaa tatataccca
    34921 cagcatccac tatagacata ataccaaaca tcaatatgaa tattaatgac aatataacta
    34981 atggcttgtt atttttaagt aaaactatta tatccttaaa cccagctttt tcactatctt
    35041 catttaccac actatatctt tctttagtag tgaagaaaca gaataatagt aataatccac
    35101 ctgctatacc ataaattatc attgcttgtt gataaccctt agctaaattt tctcctccta
    35161 atattgtact taacttagga acaccgtaag ttactataag agttcctact gatgcaaaga
    35221 acattcttac tacggaaagg tttgcacgtt ctgtagaatc ttgtgtcatt gctgatgtta
    35281 atgctccata aggtacattt actaacgtat atatcatccc taaccctata taagtaacaa
    35341 atgcatatac aaatttaccc ataggagata tatctggcac tgtgaaacat aaaatagcta
    35401 ttaatgtaaa cggcaatgca ccatataaaa gatatggtct aaatttacca tgctttgatt
    35461 ttgttctatc tacaataaca cccattatag ggtcattcaa accatcccaa atccttgcta
    35521 ctaaaaaaat catagatact gccattggag ctaatccata tacatctgta taaaaataca
    35581 ttaaaaatgc tccaactgta ctaaatatta agttacatgc taaatctcct gtagcataac
    35641 cgaccttttc tttccctgaa agcttatcac ttgctataat aggttgcttc atattgtttt
    35701 ccatgtaatt aaccccctta tcttagagct ggtataaatt tataccaact cactttataa
    35761 caatactatc tagttataaa tacttaaaaa ttattcttta ctgtaaatat gacttcacta
    35821 tctttaactt gtgctactgt tcctatttct aaatcgtact tacatttagt attttcagat
    35881 gttgcattaa tatttctaag aactatttta taatctccac ttattccttt tgtttggaca
    35941 cttattttat ttcctatttt tattgcagat acttttccta cttcttttcc aagtgagttg
    36001 tatagtatcg tttctattct attattttca tctaattcaa atatgttaat ctctaaatcc
    36061 tttaaataat cataatctgg ttttttatca ttatatccta taggaattat ggtattatct
    36121 ttaaccatta aaggcagtga catataatca tgattttcct tgtaccatct tctaccttca
    36181 agtactttat tatttaataa atttgtccat cttccttctg gcaaataata acttacatct
    36241 ccagtatcac taaatatagg agctactaat aaaccttcac caaacatata ctgacggtct
    36301 aggtatatac aggtttcatc atcactatac tcaagtacca taggtcttat cataggtata
    36361 ccagtatttt ttgcttcaac aacatattta aatagataag gcataagctt catttttaac
    36421 ttagcaaatt tacgagttac ttcaacagct tcctcatcat atatccaggg tactttatat
    36481 tcaacatttc catgatatct actatgtgat gataaaagac caaattgagt ccatcttttg
    36541 taaatatcag ctgtacaccc ttcttcaaat cctcctatat catgactcca atatccaaat
    36601 ccacaaagac ttaaagataa tccacctctt aatgactctg ccatagaagg ataattggac
    36661 aaacagtctc ctccccaatg tactgggaag ttttgtcctc caactgttgc tgatctagca
    36721 aacacacatg cttgttcatt tcctagtttc tctactaaaa gttcaaatac tagcttattg
    36781 tataaataag tatagtaatt atgcattttc ttagaatctg acccgtcgta gtattttatg
    36841 ccatatttta gtgcatccat tccataaaat tcatcttgaa caggtatcct ttcaccaaaa
    36901 tcagttttaa aactatctac tcccatgtca atcaatcttt caaggtgtga cttataccac
    36961 ttacaagcct ctggattagt aaaatcaact aaggccatcc ctgcttgcca tctatcgcat
    37021 tgccatattt tattatttcc agttttaaca aagtatcctt tttcagcacc ttctttatat
    37081 agaggtgatt tttgacctat gtatggattt atccaaacac aaacttttat acccttatca
    37141 ttaattcttt ttaacattcc ttctgggtct ggaaatactc tattatccca ttcaaagtta
    37201 caccactcaa attctttcat ccagaaacaa tcaaagtgga aagtttcaag tggtatatcc
    37261 ctttctaaca ttccatctat aaagcccatt actgtttctt catcgtaatt tgtacagaaa
    37321 gaagttgtta gccaaagacc aaatgaccac gctggtggaa gtgttggttt tccagttaaa
    37381 tttgtataat tatttataac ctcttttagg tcatttccac ctattatgta atattcaagt
    37441 gattcacctt ctacactaaa ttgaacttta ctaactgact ctgagcctac ttcaaaagat
    37501 acgttttcag aatgattaac aaaaactcca taccccttat ttgttaaata aaacggtata
    37561 tttttatatg actgttcact tgcagttcca ccatcttgat tccaaatatc cactgattga
    37621 ccatttttta caaaaggggt aaaacgttct cccaaaccat atactaactc tccaactcct
    37681 attgctaatt gttctctcat ataaatttct tttttgtctg ttgtaatata agcagtacct
    37741 gttctacttg tttcagttaa taacttgtca ttattataaa atttaatccc ccagttttcc
    37801 ccttttccta tttgtgcttt taatctacct gatataaatt catagttatc attattttct
    37861 tttattttaa tatctggtgt tttttcattt aatttgaagt aagattgttc cttttctcct
    37921 gcatgatggg taattcttac cttaattata ttttccatag gagaagatat ttctgttgtt
    37981 aacattcctc catctaaagt atttcctctt gtatttactt tgacaaacgg acaatatgct
    38041 gttaatttta cctcttctat acacatatca taaagctcaa caggatgtaa aaccgtgtaa
    38101 tttcctttgt ttaaccacat tccattacta aatttcaatt taatatacct ccttcaacta
    38161 atattagctt tgcttcaact taagtatagt ttatattatt ttttagagat atattaggta
    38221 ttttctatgc tattttatag gtctttttta gctttttatt tataaaaatg tttagaggaa
    38281 agctactcat gtaatatttt aaaatcccat tttacatatt tatttttaaa tttaaactca
    38341 tgattattac aaattatcta aaaaaggaga tatctcaaaa taaaaatttg aatcatctcc
    38401 ttttttatac aaaaaaataa agggtattcc taagaatccc taatctatca gcccagtgat
    38461 aggatacaat gtttataatt tattcatatc taatatacat tacttgacca attccattat
    38521 tagcttcttt atcagtgatt tctattttaa tagttacatc gttttttttg cagtacttcg
    38581 ctaattctac accagaacga tttttaccac taaaatctaa agaaaatggc ttatcatatt
    38641 caaaaggata ttcaacagga ttaccttctg gtgctaatgc aaacatccca tatggtgtgt
    38701 tcataaatcc tattacagca atcacaagct ttgatgggtc taaatttgat ttactaccta
    38761 taaatgtaac tgtatttact gatgaattaa ttacaataca tcgaacacct tcatacatta
    38821 catgtttgtc ctttatatct cccaattctc caaaagcctt tgccccttct tgatgtggta
    38881 acatagtgtg cttcccaggt ggtgctggtt tctgtgtctg ttctggtttt accgtctgta
    38941 ctattgcacc aacttttgga tatgctgtct tatcaaatgg caatggatgt gtaaggctct
    39001 tgtatataat gtcctttcct gctgatttat tagcatcaat gtctacatga tacaaacgcc
    39061 catcaccaaa acggataaga ttccactggt ggtcatttga tgtactatgg acataataac
    39121 attcaattcc catagcgtca cacaaagctt tcatgctcct agccattcca gaacatgctc
    39181 cctttttagt aaccaatgta taagcagtat tggctccctc tactgcgttc cagtcaacat
    39241 atgttgtgtt atttttaatg tgattatagg caactaaaat cttagcatct gtagtcatat
    39301 tctttgtgat tttcttgttc ataaaatctg ctgttgcttg cgctactgag ttcagttggg
    39361 cttgtgacag cttgggtcca tatacactat tagttccagt gacatagctt tttggtgtct
    39421 tcgttgttac ctccttggct gtcataccat aagctgtcat actcatacct gagattaaaa
    39481 ccattgttgt aatcaataac ttggtagcta acttcctaat tttcttcata cttaatattc
    39541 tcctttataa aacattgtta cttcctattc tctaccatta ataaaattaa tttaggattt
    39601 aaaaaggtgg attgtcaaca tgtatatttc tccattcata cgttcgtgaa atatttaaat
    39661 ttcattgaaa atctaataga tattttctag ataatttgta tacaatacaa ctcgcaaatc
    39721 agtgtgtttg ctgttagttt gataaaatga tgatgattaa tatattcgga atctttgacc
    39781 tataataaat agtactattt tcaatcatta gtaatggtaa gaataaagag aattatcaat
    39841 aatacagtta aaatcaactt tgtatacatt tcatatattc tccctagaca atattataca
    39901 aattataata tgtatattca atacattttc tggaagttat atcaatatgt gtaattatat
    39961 attacccacg gttgaaagtc atgaaataat atgattgata gtagtaaatt tcaataagta
    40021 aaggatttag aaataatgaa aaataaaata acatataaaa attaaaaaag ggggtgaatt
    40081 taagatttta ttagaaaaaa ttaattttga aacatcccct ccttttttat cctaaatatt
    40141 caatttcact aaattttgta tatctattca aataaatatt ctccatttgt ttctataacc
    40201 ttcttatacc aattaaagct cttcttttta tatctattta aagtaccact tccatcatca
    40261 ttacggtcta cataaataaa tccataacgt ttcttaagct ctgctgttga cgcacttact
    40321 aaatctatac atccccatgt agtatatccc atcaaatcaa caccatcatc aatagcttca
    40381 gcaacttgct ttaagtgatt tctcaaatag tctattctat aatcatcatt aactgtaaac
    40441 tctccatttt cacccactat taattcatca aaagctccaa atccattttc tactataaac
    40501 aatggttttt gatatctatc atagaattga ttaagtacat atctaagacc ctgtgggtct
    40561 atttgccatc cccattcact ttcttttaat gttggatttt ttgctccacc catgatattg
    40621 cctttactac ctttaatagt cttatctgaa ctttcacaaa tactcatata ataactaaaa
    40681 gatataaaat ctactgtatt ttttaatatc tcaatatctt catccattac atctatatgt
    40741 atattatttt ttctaaaata acgttttgaa taacttgggt atttacctct aacatgaata
    40801 tctgcaaaga ataaattttc gtgttccttt tccattgcac aaatcacatc atcaggattt
    40861 ggagttaatg gataaactgg catagataac accatacatc ctatcttaaa ctcaggattt
    40921 atctcatgcc ctatctttac tgcttttgca cttgctacca attcatggtg tatagcttga
    40981 tatatttgat tttttgttaa cttttcttta ggagtattaa ttcccccact taaaaatggt
    41041 tcatgtacta tagagtttat ttcattgaat gtaagccagt actttacctt atctttgtat
    41101 cttttaaaaa ctgtagttac atacctacaa taaaaatcta ttaaatcacg acttatccat
    41161 ccatcatact tttctgccaa atataatggt gtttcatagt gagacaaagt aactaatggt
    41221 tctatatcat attttctaca ctcatcaaat aggtcatcat aaaatttaag acctttttca
    41281 tttggctcta gttcatctcc cttaggataa attctagacc atgctattga tgttctaaat
    41341 actttaaatc ccatttcagc aaacaactta atgtcttctt tgtatctatt ataaaaatca
    41401 attccaacta atttcatatt atcttctgtt ggcttttcag ttcttggagt cataattcca
    41461 tttggagtca catcctgtat gctaagtcct ttcccatcta cattatatgc accttcacat
    41521 tggtttgcag ctactgcacc gccccataaa aaattttctg gaaatctact cattttctat
    41581 catctccctt aattcaatat taaacgttac ttaaaatata atctttaaga aatttcttat
    41641 gttatattta ttaatatatg tacaataatt cactttctag ttaatcaaat ttatatcact
    41701 gctgttaata aatcagattc tatcatcaac tccttatcat tagtacttat tattatatct
    41761 tgaaattctg atgagttagt cacaataatt ggtgttattg ttgaataccc agcttcactg
    41821 attttatcaa tatcaaacgt aactaacaaa tctccagcct taactttatc tccagcgtta
    41881 atatgcattt cgtagtattt tccttccaat tcaactgtat caattcctat gtgcattaat
    41941 atttctacac cttcattagt ttcaaatcct aaagcatgtt ttgtaggaaa aacaaatttt
    42001 acttctccat ctgcaggtgc atataattca cctttatatg gttttattgc aattccttgc
    42061 cccatagctc cttctgaaaa acactggtca ggtatatctt ttaaagatac caattctcct
    42121 tgtaatgcac tctttaacac tacactatct ttttttgaat ctaaaacact tttatatgta
    42181 agtccttcta aaatcatgtt atcattaaat ccccatataa aagttgtaac agctgaccct
    42241 acataagcaa tcgcacatgc tattaagaaa ccaataaaac caacacctat atatgcaggt
    42301 aaagtaatta aacttgtccc aataaatgct cctacacctg tgcctgccgc tgctgttata
    42361 gcacctgcta ctccagaaaa tatacttgca ataataaaag gctttttaaa ctttaaattg
    42421 actccatata ttgcaggctc tgttattcct gttaatactg ccgaaactgc tgcaggtcct
    42481 gctatagatt ttaaatcttt atcttttgtt tttaaaaaca ctcccaaaca agctccagct
    42541 tgactaaaat tattaggtcc agttattaca aataaagtat ctctaccata tgtagctata
    42601 ttatttaata ctataggtac aaatccccaa tgcaatccaa atattattac tgttggccat
    42661 attacagata ctaaacctcc tgcaattata ggatttatac tcataaccca cttatatcca
    42721 tcagctaaat atactcctgc atagcttgta actggtccaa tagttaaata tgttaatgga
    42781 acaataatcg atatacataa tagtgggact aaaaaacttt ttaatatact tggtattatt
    42841 ttatttaaaa atgcttctac cttagcaagt gcccatacac taataattgc cggtatgaca
    42901 ctagaagtat aacttactag aataactgat aatcctaaaa aatttatact ttgaccttca
    42961 ttatataaag caactatatt tggatatact aacgatgctc caatgataaa tgctaaaaat
    43021 tgatttgcct taaaatattt ggctgatgta aatgctaaag ctataggtaa aaaattaaaa
    43081 attgcatctg ctgctgcata taaaatcata tatgcaccgc tattctcttg taaaactcct
    43141 actgtatttc ctagtattaa taaagctttt aacatacccg cacctgaaag agccatcatt
    43201 aaaggagaaa aaattgcaga tatcgcagat atgaatctat caataagttt ttcttttgct
    43261 ttctctttat cttctatatt atcaacttgc gtttcaagta tagtcccttt tacgagttga
    43321 ttgtatactt cagaaacatg atttcctatg actacttgat actgacctcc actttctact
    43381 actgttatta caccattatt tttttttaga ttctctgtat ttgcttttcc tatatttttt
    43441 aacttaaacc ttaatctagt tgcacagtga gtaacatatg atatgttttc taatccacca
    43501 actccttcta ttatctcttt agataggtca caatattttg tagacataat aaacctccca
    43561 catttaatat aaaatcaatt tttatctcaa ataatcaact atatcaactt ctcttttaca
    43621 tgttttgaat tacttactga tattttagaa aacgatttca aattaattat aaacattcta
    43681 tgtatcttat atttttatat catttagttc aagtatatta attaatacta aatatttact
    43741 tctgtaaact ttttccataa ttttcaaact attaatcctc gttaaattta atcaaatcat
    43801 gtcttaagaa gttaacatca cttgttagaa cattagtatc ttcactcctt tctaagtcta
    43861 aatattcttt atatttttat agtagcataa ctaattgttt ttgtaaatat ttattatttt
    43921 taaactaaat atttatctaa ttattttcat ttttttattg aacacaaaaa tcctaagcaa
    43981 tatttcatat gcttaggatt ttgaaaattt attacaatat ttatttttgt cctataatta
    44041 ctatatcttt attacatgag tgcatcttaa ataaagtact atctttttta aattcaatta
    44101 aagggataag aatattcttt gtttctaaat caaacaaatg aaatttatac tctgataaat
    44161 tttcacttat tttaacatta gtatttatcg gtatgtatag tacaacagat gatttatcat
    44221 aattagttgc atatcttatt tcatctgtat cattaacaac aagattattt ttagggataa
    44281 tattttttaa attattttgt tcaagaagat actttatcat gccataatca aaagcacctg
    44341 gtaattgaag tgcactttgc cacaataaag gactgtcaaa agcttctcct attcccataa
    44401 aaaatgtcga atcattagtg tgccaactcc atatcccatg agctccatac gttaatccag
    44461 cacaacctcc agatagtaca ctttgccatc ctgcctttct tatatcatag tcattaaatc
    44521 taccatacac ctttctacta tagcccatct gctcataaca aggttctgaa tttaagattg
    44581 gtttacatgg atatttacta taaaatactt ctgctaagta gtaaggcata ttggtaaatg
    44641 aactattatg tcctgattga tacatataga aatcaatttt acttactaat atctctggta
    44701 tttcctccag cctccctctg atatggagag tttttaaggt atttggagat actttattaa
    44761 aaaactctaa tgctttattg taatattcta tactttcttc ttttccaaaa tcagtatccc
    44821 cactaattaa ataaataggg ttcatatcat taaaagtttt atttactatg tcaaaataag
    44881 ttgataaaaa cgatataggt attatatttt tatccataat agcacttgcc catgttcctg
    44941 gtacataatt tgaccacaat accactaaag ctaattgaaa cccatattct ttagctaata
    45001 aacacatctt tctagcattt tcaaaatata gtttattcaa agttgaatag tcgaaagctc
    45061 catcatcctt tatatcaaat ggtaacaact cattatgctt agcacttcta tcccattgag
    45121 gaagtatatt tacttgaaga gtattaaatc cttgttgctt cctcttttca agataaaacc
    45181 tccactcatt aaaatcgata tttgtaaatg cactccaaca tgtatctgct aaataaaaaa
    45241 aatgctcttt atccaaagta aaagttctat tgtcagatgc tacttttaat ctactcacaa
    45301 ttacaaccct cttccttaac aatagtctta aacaagatta aaactattac ttattaatat
    45361 ctttaacact atctctttct attaattctg tttctacttc tatctttaac ttcagattaa
    45421 tttgattatc aatcttatct ataagcctat ttacagctat tttccccatt tctacagtct
    45481 gtaccttaat agttgttaaa gcaggattag caagtgcact aaaagttata tcatcaaatc
    45541 ctattataga tacatcttca ggaattttga ttcctttttc attcatcgcc ttcattgctc
    45601 ccaaagcaat tatgtcattg aatgcaaata atgcagtcgg tagctctact ttttcatcta
    45661 ttatcttgtt catatcatta taagcaccat ctatagtagg ctctaataaa aacttatatt
    45721 cttgattttg ttttatattt aaatcattta gagccttatc aaatccagtt gctctatatt
    45781 caaaattctt tatacttcta gaacttccta agtaacctat ttttttatgc cccttttcaa
    45841 caaaatactt tacagcagag tacgcaccac tgacattgtt tatacaaaca tagtctgaac
    45901 ttttagtctc atgataacta tctactataa ctataggtat agatatactt aaattttcaa
    45961 aaaatcttaa atccgcttca ttcatttctg ttgccaacaa taaaatacca tctacatttt
    46021 tttgtcttat tattgtatca atattctctt ttgaattaac atcatctcta acatgagaaa
    46081 tcaagagttc ataaccatta ttacgacact ctctttcaca accttctata agcgcagaga
    46141 aaaaaggagt atcagaaaca acatagccat gctttttaaa tactattagt ctaattgcat
    46201 tatcctcatt ttttttctga tttctaaaat aacctttttc ctctgctatt ttaattattc
    46261 tttctttagt ttcttttcct acaccttttc tattattcaa tgcatttgaa acagttccag
    46321 gcgatacacc tgctaattta gctatatctt gcattatagt tttactattc attttatcac
    46381 taccttttct atattaaatg attaaattca cactccataa attatagtat aaggcaataa
    46441 ttaaataaaa taaacactta agctaaatat ttagtaaata tttttatttt actaatgctt
    46501 ttcaattttt aataaacaaa atcttattct cctcttatcc acgcctttac atcctcttct
    46561 acattatcat aaaaatctag atttaaatcc ggtaaatact tacaagcttc ataaatagca
    46621 ggtagtacat catgatgtat tccaacacaa tgatgcacat atggaccagt tacaagctta
    46681 tcctctaatc ttgtcaagtt ttctacttca acccaaagat atgttccttg tatataaggt
    46741 ccttctattc cttttgcatg tcctaacaac aaagaatact ctccattatc tccatcaaat
    46801 cttaataaag atatattccc tccttttatt tctgcaaatg atgaacctac acatctactt
    46861 tcaagagcaa aaggaactcc aaattttgct ttttctcctt ctttagtcaa agatataggg
    46921 taacatccac aatgttgaag caattctcca tttttattgg ttggatgtgc tactgtccaa
    46981 tcagcaaaaa acggtggtgt tttccccatt gcagcagatt gagctatgac agaggttatc
    47041 gctccatgta tatcagtttc acaaactact ggtatcccct catcagtaag aatagcattt
    47101 gccatacatg gcattatctt aagctcctct tgtaaggcat tccagcattg aatggctact
    47161 gctttacatc catacttttc agttaaaagg ttaaatgaca acttaagtgc tgctacccta
    47221 actacactct catcttcaac atttatttct aaattttctc ttagaaactg tattgtttcc
    47281 tttaattttt cattattttt tgattctatc tcttttacag aactaacaaa ctccgataaa
    47341 gaaattggat ttatttgaac tccaaacttc tcaagtagtt caccttcatt acacatcata
    47401 gtccaaaaag ataacggtct agttgatatt tgaagtattc ttaaattttt aagttctttt
    47461 actacattaa ctgcggcaat aaaattgttt actcctcttt caaaagcttc atcttccaga
    47521 gatgcatttg gtatgtatgt aaatttaatt ttaaatcttc taagtatctt acctgtagca
    47581 aatagaccac attgactatc tctaagtctt gttccatctt ctagtggagc tccatctcta
    47641 ggtccccata aaagaactgg tagatgtaat ttatgagcaa ctttagccac caaatcctca
    47701 gtaccaaagt tacaatgtgg aaaaaacaaa gcatctactt tctcctgttt aaacttatcg
    47761 acaaccttct ctacatctga ttctttaaat aacagtcctt cttcatttat atcctctata
    47821 tcaacaaaat ctatattcat ggattttaat ttcttactta ctaattgttt ataccttata
    47881 gcttctttct tactaaatat atttctacga gttggtgcaa ctcctagctt tattttatac
    47941 tctatcatat tatctctcct ataaattaac attttggcta tttaaatctg tcatatataa
    48001 tacacttttc attgcatttt tccattttct atacaaattt tctctatttt cttcatttac
    48061 attagaagta tagtttttta tatttttatg taaattttta atttcttcta tgccattcca
    48121 aatacctaag cctatacctc ctaagtatgc agaacctaaa gctgacaact cttcattttt
    48181 atttttagca attttgcaat caagtaaatc tgctaaaaat tgattatata tatcatttac
    48241 agttactcca ccatcaacac ttaaattttt aactgttata ttactttcca attctaatat
    48301 atcaatagca tctttaactt gatatgctat tgattccata gcagctctca ttatatgctt
    48361 tttagtcgta tttctagata tacctactat agatgccctc gcattgggct tccaaaaagg
    48421 tacaccaatt cctataaatg ctggtataaa atatacacca tcattatttt taacttcttc
    48481 gacagccttg ttaaactctt caaaatcaga aaatagacct aattcatttt ttatccagtt
    48541 tattgtatct ccactagaat ttacaattcc ttcaactgca tagctaacta tatttttagt
    48601 aatataacca acagtcgata caactccatt ttgagaagga ataaagttct ctcctacatt
    48661 tatcattata gaattaccag taccaaatgt agactttgcc atacctactt caaaacatct
    48721 ttgaccaaac aaagcacctt gagaatctcc aattactcca ctaatcttaa gattttctga
    48781 aaaatatcct tcaatattag tttctccaaa tatttcatct gatggatata ttttgggtaa
    48841 catactcctt ggtatatcaa atatgctcaa taaagaatcg tcccacttca aatctcttat
    48901 attaagcaat aaggttctac tagcgttagt atagtctgta gcatgacttt tcccattagt
    48961 aagattccaa actaaccatg aatcaatatt accaagtaat aaatcacctc gttcagcttt
    49021 agctctagct ccatctacat tgtctaatat ccacttgact ttagtagctg aaaaataagg
    49081 gtctaatttt aaaccagtct tttcttgtat ttcattttta tatacactta gatttttgca
    49141 tatatcacta gttctcctac attgccatac tattgcatta tatacaggct tacctgtatt
    49201 cttatcccaa attactacag tctctctttg atttgttata gaaataccag ctatatcccc
    49261 tgtacataat tcatgagata tgattatttc ctttaataaa cagattacat tactgtatat
    49321 ttcaataggg tcgtgttcta tccaactatt attaagataa tattgggtat gtttcttaga
    49381 taatttattt attattattc ctctactatc tataagcagt acctttgttc ctgatgtact
    49441 ctggtctatg gttaatatat attttttatc catattttgc ctctttaatt ttcactaaat
    49501 agcatttcct tagctatttt cactatattt tcgctattca atccataata attaaatact
    49561 tctttactat tacctgatat aggagattca tctgctattc ctaacacttg catcttaaca
    49621 gggatatttt ggactacgac ctctgatact gctgctccca atccaccata tatactgtgt
    49681 tcttctattg ttataattcc cttcgtttct ttagaagatt ttattatagc ttctttatct
    49741 aaaggcttaa ttgtatgcat atttattact ctacattcaa taccatgctt ttcaagttct
    49801 atagctgcat ctagtgcaat tcttactgtt tcaccagttg ctatcactgt tatatcattt
    49861 ccactatgta attcattagc tctacctatt ttaaaatcaa aatcttcatt ttcatataca
    49921 tcttcaacag gatttcttcc tattcttata taagctggaa tatcactttt atacaattct
    49981 tgtatcattt tcttagtttc atatctgtca gccggaagca gtacttgtat atctggtatt
    50041 gctctagtta ctgctatatc ttgaagagaa tgatgagtca ttcctagcgc cccataactt
    50101 atacccccac ttattcctat aagtttgaca ttatttttag aataagctac atctattttt
    50161 atttgctcta tacttctcat tgataaaaaa cacgctggag aagctacata agtttttttc
    50221 ccacaagatg ctaatcctga tgcaatacca actaaatttt gctctgctat tccaacttca
    50281 acaaactgct ccggatataa ttcagcaaac tctgacattg aagcagaacc tctagaatca
    50341 ctagttaaaa ctattatatc tttatcatat tttgctatat ccactaaagc atcacaaatt
    50401 actttacggt ttgctacatt attcatctat tttccctcct ttaaatcttc aactgctttt
    50461 atgtattgct cctctgttag cactccatga tgccatttta cgttattttc cataaaagat
    50521 atccccttgc cctttatggt attagctatt atcattgttg gcttattttt tttcaatggt
    50581 atcttatcaa aaacttcaac taattctgtt atattgtttc catctacctg cactactttc
    50641 cagccaaagc tctgccactt ttcttgaaga ttttcaagtg tcataacttc ttctgttgtt
    50701 cctgatattt gcaatttatt tctatctata attgctacta ggttatctaa cttataatga
    50761 ctagctgcca tggctccttc ccatatagac ccttcagcta attcgccatc tcccataagg
    50821 gtaaaaactc tgtaactttt cttatcacgc tttcctgcta tggccatacc cacagctaat
    50881 gaaagaccat gacctaaaga acctgtatta acctctatcc cttcattttt tttgtttgga
    50941 tgacctataa gtgttgagtt aaattgacta tatgttttta acttatctct actaaagaat
    51001 cctttatcag ctaatataca gtatagagct tctgctatat gccctttact taatataaat
    51061 ctatctctat ttgagtcttt tgcgttttca gggcttatat tcattatatg gtaataaaga
    51121 gttgttaaga tatcagtact agacattgca cctcctatgt gacctgcttt tgcattatat
    51181 acaacatcta atatttcttt tcttatttga tttgattttt cttctaacct tttaatctgt
    51241 ttattcatag tcccctccat ataaatctcc ttttttatat ttagtaaata tttagttgta
    51301 tttttatatt atcacttatt ttaaaattag taaatattta ttatttatat gtggtaattt
    51361 ttagttatat ttttatttat attgctaaat atttattcaa tagaagttaa aaaatggaaa
    51421 ttaaaattac atcggatatc caacattata agtaaaatct ataatttaca aaaaaaagtg
    51481 agtgtctcaa agtgaacttt tttagttcat gaggcactct tttttgtatg aaatcaaata
    51541 tattttcatc agtttaacaa agaaaaagag tcttatctct attttgagat atactctttc
    51601 ttacagattt taatactaca tttattttaa ttactcttat tttattatca ttagatttat
    51661 agttgcaatt tttacaacaa agtataagct ttttcttata ttatttacac aacttttttc
    51721 tttttaacct ataaacttaa ttatacattt tgtagattta tttccttaat tcttaaagtt
    51781 ttttctgaac attttataat gtcatctttt tgataaatat ttatatattt acttatcttc
    51841 tctaaactcg tcaagtccaa ctataggtat ctttaaatta tattctttaa gtagcttttc
    51901 tagctcttct ataaaaatac ctttcccatc caccatttgt atatcattta ttttatccat
    51961 caattcattg caaccactta actcaccaaa ccaacgttta gaactacatg tcttattata
    52021 accacaactt ggactgccat ctattgcaat gatacttttt atatcataat cattttttaa
    52081 atattcatca aactgcctta catgaggtat taacatttgc ctacattgtt ctctaaaaaa
    52141 caaattgtca aactgttctt ttacatgtcc ccacctattt attccataca taatcatttc
    52201 tgggcatggt agttgaatta ttccataccc tttatttatt aaatttatcg ctatattttg
    52261 tgctccctta aattctgaca atccctccac tttagaatta caatttaata tacaatgaca
    52321 tactactaca atctctctat ttcttttcat aataatctcc ttagttattc ttaattttaa
    52381 tgatactaca tattttgata attatattat ttatttgttc tatatttcca atattctata
    52441 tagaaatata caattagtaa tcttttataa tctatactat gataaatgta tatatttttt
    52501 taggaggtat tataattgga tactaaaaaa gtcacatttt cttcaatgtg catagttatt
    52561 aatattgtct taggtatggt tatatctatg ataaatatac cattattatt tttagataca
    52621 gttggtactg tacttggggc tgtcgtatta ggtccttttt ggggtgctct tattggtggg
    52681 tgtacaaact tagttttagg tgttatatca ggtcctacaa atataccttt tgctcttgta
    52741 aatattgttc ttggtcttat tgttggatat atttctaaga aaaaaggttt tggttataaa
    52801 gaagctatta ttacaggagt aattttatct attgtttgtc ctttgattgg tactcctatt
    52861 tcagttttat tgtttggtgg tttaagtgga agtggtgctg atttattggt tggtttttta
    52921 gttcagtctg gtcagaagat atttactgct gcgttctttc caaggattct tagtaatata
    52981 gtagacaaac ctttgtcttg tattatggtg gtatatttta taagtaaaat gcctaaaggt
    53041 tttataaaac aatatagtaa aagtacgtct agttattctt agtaaatttg tacatactat
    53101 atgatttttt aaatgttata acaagtttat acaaatatat ttgtataata tctttgctac
    53161 tttatttttc attaatttta gtattagtga tttaattatt tattatctgt attaatttaa
    53221 ttaaatacaa cctcttaata taaatttaga ttctaaaatt atatcaagag gttatatttt
    53281 tattttataa tatatttaaa gttttataac aatttataga atatatgttt ttattttagc
    53341 taaaatacct ctctaaaaat cattttttac aagtatttct tatattaaca aatatattct
    53401 cattttctat aaacaactca tacatatctt caaactctag tatacaatat ccatgagagt
    53461 cattatctct taatttttta agtgttttta ataatatctt ctttattcta tatttctaat
    53521 ttgacctctt aaatatacaa actaaagtaa gatatctact atagacatct tactttagct
    53581 tcatttatga ataggtttta ttattaacac ttcactatct ctattgcttt tcctacacat
    53641 ccacaaactt ccatcctact cttaacaaaa tctttaactg actctaaacc ttttttacca
    53701 tatttcttag ggtcaattac ctctgggtca gaattaagca catccttaac cccattgcta
    53761 taagcaatcc ttaattcagt tgcataatta accttgcaaa tccctctttt tatagactcc
    53821 ttaataacct catctggtat tccagaccca ccatgtaata ctaatggaac tgatacaacc
    53881 tctctaattt cagataatct atctaaatca agctttggct ctcccttata taatccatgt
    53941 gccgtaccta ttgctactgc caaagatgat acccctgttc tctctacaaa ctcttttgct
    54001 tctaatgggt ctgtatatgc tcccccatca ccaccatcta aatcgtcttc cttacctcca
    54061 actttaccta attcagcttc aacaggtata tctgaaggca tacatgcatc tacaacagat
    54121 ttagatattg aaatattatc ttcataactt tcatgagaac catcaatcat aatagaagta
    54181 tatccaactc taagtgcctg catagctagt ccaaagcttg aaccatggtc taagtgcatt
    54241 gccactggaa cacttgcctt ctctgatgct acctttacat tcgctaaata ataatctagt
    54301 cctgcatact ttattgttga aggtgttgtt tgcaatatta ctggtgattt aagttcttca
    54361 gcagcctcta ttactgccat aaccatctcc atattttcaa cattaaatgc acctactgca
    54421 taatgccctt cttgtgcatc taataatatt tgtttagttg tcactaatgc cataatttct
    54481 cctcctatat gtttatactg atttaatttc ttcgttattt aattttgata ctatttctct
    54541 acttgttttg ctatttaata actcatttaa aaattcttca ttcattaatt ttgaagatag
    54601 ttgagataat gtttttaagt gtaaattatc gccattatct gtagctgcta tcataaatat
    54661 aatatgtgcc aagcttccat cttctgattc aaagtcaaac ccttcttttg atagacctac
    54721 tgctacacgt ggtaccttta ctgcatctgt ttttgcatgt ggtatcgcta tccccatacc
    54781 aaaacctgta gatgatattt cttctctttt aaggatttct tctttaaact tctttttatc
    54841 taaaagaaca ctagatttat caagtattcc aatcatttca tcaattacat ctgttttatt
    54901 ttttccctta acatctaaaa ttactgtttc ttcgctatat aaagagatat tattagatac
    54961 gttttccgat tctgcacttt catttttatg ttcatctttt gttacatttg tattttctat
    55021 agtatttttc tcatttacta ctttaggtgt aaccatcata taaagtacag cacctactaa
    55081 tgaacctaca aatatacacc ctacccataa aagtggctta ttgactaatc ctagaaccaa
    55141 aaaccctcca tgtggagctg gtacttctat tttcattata taagttaaaa ttgatgatat
    55201 tgatgatgca atcataagta ctggcaacac ttttaatgga ttttttgctg caaaaggtat
    55261 tgccccctct gttatatgag tactacctag tatataattg attaatcctg ctgctctatc
    55321 ttcttctgta aatctatttt taaataaagt agatgctatt gctattacca atggtggtgt
    55381 tatacaagct gcagatacac ctgccataaa taaataattt ccctgtccta gaagcatagt
    55441 tccagttaca tatgctgctt tatttactgg acctcccata tcaaatgctg acatacatcc
    55501 tattactatt cccaaaatta tagggcttga attttgtaac cccgatagaa agttcatcat
    55561 agcattgtta agtgctgaac atggcccacc aagtaacaac attgctacac ccacaagacc
    55621 tacgctgaca ataggaatta taaaaatcga tttaagacct tctaattgtc gtggtaattt
    55681 tcttaacaaa tgtacaaata gtttaactaa gtaacctgct aaaaatcctg atatgattcc
    55741 acctaaaaaa cccgaacctg tatcaaatga tatcattcct ccaacaagtc ctgccaacat
    55801 accagctctt cccgatatag attgagctat aaatgctgcc aatacaggaa ccatcaagtt
    55861 catagaatat ccaccaacag attttaatgt agctgctatt tgattatatt gttctgaatt
    55921 tgggtcaaat gaataaatcc cccataaaaa tgatatagca gtaagtactc cacctgctac
    55981 tactaaaggt aacatgtgag atacaccatt cattaagtct ttatacaact tttgaccaaa
    56041 cgataaattt ccttcttctg caattttact gcttgataag tttccttttc taatagctac
    56101 ttttccatca atacatcttt gtataagttc attagcctta tgtatacctt ctttgacagg
    56161 tacttctatt actggctttc cattgaatct gtccatatca acatttttat cacaagcaac
    56221 tattattgca tctgccattt cgatatcttt tgctgttaac ttattttcta cacctatagc
    56281 tccattcgtt tcaactttta tgtcacagcc taattccctg gctgaatttt ttaatgcttc
    56341 ttctgccata aaagtatgag ctattccagt tggacaacct gttaccccta gaatcatttt
    56401 ctttcccatt tttataccac ctttctgact cttatacttt ttatataatc ttccacattc
    56461 tccaaattac ctataccatt actttcagcc acacttgctc ctgttgctgc tgaccttttt
    56521 aatgcttctt caatatgttc tggattttcc agccatatac ttaaaaaagc agctaatgca
    56581 gaatcaccag cacatgcaga gctgactact gtaactggtt gagcactagc ataataaatt
    56641 gattttccat tataaaaata agaacctttt tctcctaaag ttagcaatat attttgagca
    56701 ccttttaaat ggagtaattt aagtacatcc ttaatatctt cttcatctct tacaataatt
    56761 ccaaatatat ctttgatttc ttcatcattt ggttttatca aatatggatt atactgtagt
    56821 aactccttta attttggtga acttatatcg agtattgtct ttatactttt attttcacaa
    56881 attttaaata tatcctcata gtaattatca tcaataccag gaggtagact tccacttatt
    56941 gataagtaac ttatatcttc taatgactgt atcttatcta gcatatctag tttttgtttt
    57001 tcgtttacat atgacccaga gtttacaaat ttaaattcat cacttccatc atttaaaaat
    57061 atatttatac gagttgtatc ttctacccaa gtaggcaata cgtcaaatcc tctcttttcg
    57121 ctttcttcaa ctatatattt tcctgaaaat cctccaaaaa atcctaatat cttagattct
    57181 ataccataat gacctagtac aaaagttaca tttaatccct ttccattagg agaatataca
    57241 gcatttgatg tacgatttac taattttctc tttatcccat tagtagatat attcatatct
    57301 attgcaggat tcgtagttaa tgtatatatc attgtcttcc cccttgcttg tgctgtgtat
    57361 gttttcatta taataaaaaa gtctatgaaa atcttttcac aaatagaaaa tcgattttca
    57421 tagacttttc aatttaattt tcagaattat tatatctgac catataatct ataattatcc
    57481 tagatataat atacaagggc aatctggaag atacttcata ttcagaaatt gatatatgtt
    57541 catgtttgta tcctacaata tataaatccg aatactttat aagttttgca ctttcactac
    57601 aacagcaagt tataacctta gctccaacta aattggcatt ctgtgctgat tctacaagct
    57661 ctatggtatt tccattcaat gaaaatataa ttataagttc gtcttttttt attgatttag
    57721 attttatttt cattatgttg gggtcattta taaaaacaac attaaaatca agtaattgca
    57781 atttaagact aaactctttt gctacatatt cagtaagccc tcttgctaaa atatatatct
    57841 tactagattt atttatagtt tttattatat tgattagtgt agttaaagat atttgttcta
    57901 taactctctg tgcttctata aaggatttat ttattatatc tcccatattt tgtatatcat
    57961 cattttcatc ttttactgtt aatctatacc taagttcatt gaatccattt aaaccacatt
    58021 ttctaattgc tcttgaaacg gttgctggag atgaatatgt ttcatgagca atctctacta
    58081 tagataattc tggtaatatt gattcatttt catttataaa tttaattatt tcaagttccg
    58141 tcttcgttag attttcagaa ttacttttgt ttagctcaat tatcatatgt tatctcccct
    58201 tatataagtt ttatttgtct aaatttatcg agtaatataa tatattacct cttaactact
    58261 tatttttata tacaattaag atttagtcaa tgtctatata tgtaaattta taatataata
    58321 attttatgct tcaattaatt atgtaattat tagagtattt tgtaataaaa attggagtta
    58381 ctcaattact gaaactgagt aactccaatt tttacgacct caaattaact cgaattattg
    58441 aaaatgattc ataaacatta tccatactct cacttatcaa tttatatatt tgagtaatac
    58501 ctttttttat taacagaaat catcttacta acaattgaaa ttgtagttcc agtacataat
    58561 attgaaaata tagttccaaa ccctaaattt ccgcctaaat atacacctaa aattaaaaat
    58621 attacatctg ctatagtttt taaaacttta tatggatact taaatttgcc ctcaatatag
    58681 attaatatag catctaaagg gctcattcca atgtcaaatt ttataagcat tgcaaatcca
    58741 ctacacataa gtatatgtcc aattataaag ctcattattc taatgataat ccctaaacta
    58801 cttatattaa aatctaataa taagtatata tacaaatcta taaatattcc tgctactagt
    58861 acataaacac agcttcctaa tcccaaactt tttttattca atagcaatgc tataagtaat
    58921 agagttccat tatatattag ccctgctatt gtataactta tacctaactt tatatgtata
    58981 ccctcattta aaagtgtaat tgcatcacta ccaaggcttg actgaagtat aagagatata
    59041 ccacatccca gtatatttat aattaaaatt acaaatataa atttttttat gacattcata
    59101 attaataaac caccttattt ataattataa tccctcttat aaaactgtat taataacata
    59161 gtatttataa gagggattat ttatatttaa aaactattta cttttctttt aattcttctc
    59221 cattagttct tattacattt tgataccaat aaaaactatc ttttttataa cgttttttac
    59281 ttccatttcc attgttatct atatctacat atataaatcc gtatcttttt tccatttctt
    59341 gagatgaaca acttactata tctattggcg accacataca ataagctaat atttcggttc
    59401 catcagctat agcttcacct atttgttcta tatgttttcc taaataatct attctataat
    59461 tatcatgaac ttttccatct tcaaatttat catgcattcc aaatccattt tcagctatca
    59521 ttattggctt ttggtatcta tcataatatt gagataaagt attgtataat ccttttggat
    59581 caattgccca cccccaagga tttgctttta aatatggatt atttatatta tcagttggat
    59641 tcatggtgtt tttacttgct gatactgttg tagaataata gtatgataaa gctagaaaat
    59701 ccatagtatt ttcttttaag attttatcat ctccttcctc tataactata tttatgttat
    59761 tttctttgaa aaatctctta atatagactg gatactctcc cctaaaactt acatcagtga
    59821 aaaaatattg tagcctattt ctttttaaag caaatactac attttcaggg tcacaatctt
    59881 ctggataaga tgtacaatct gccatcatca tacctatcat catatctgaa tttatttctt
    59941 ttccaagctt cttagtcaaa gctgtagcta tgaattgatg atgaatagct tgatatctag
    60001 cctcttgtac attatctact tggtctacac aaaatgcaac tgaattaaat gattcataat
    60061 gtattaaatt tatttgattt ataactatcc aatatttaac tttattttta tatctattta
    60121 gtattaattc tgcatatcta acaaagaaat ctaccacttt tctattagac catcctttat
    60181 attttaatac taaattcaaa ggagtctcat agtgaagtag tgttacaata ggttccatac
    60241 cattatctat tacttcattt ataagattat cataaaactt taatccctct tcattaggct
    60301 ctaaatcatc tccatttgga aatattctag cccaatttat tgaaaatcta aaacacttta
    60361 accctagctc tttcaaaagc tttaaatctt ctttgtatgt atgataaaag tctattccac
    60421 tacgcttagg ataatatcca ttattatctt tcatagcaaa ctttattctt tctatagtca
    60481 tatcagactc ataaggttta gatatatctc tatctttatc atacatatgt acatcagcta
    60541 aacaccaacc tttgccacct tcattccatg caccttctaa ttgattagct gctacagctc
    60601 caccccacaa aaaatcttta ggaaacttac ccaatttaat cactccttat tttatttatt
    60661 taaatcattt actattattt accttatatt ctatagactt tactattcct actaaagaca
    60721 tagttatatt taactcgctg aatatggtca taagagtatc ttgagcatgt gcaaataaca
    60781 gcgaatgtgc tcttttctct ccaccagctt ccccttgtat aatcttggtt tgagctctat
    60841 gtgcttctgt cataaaccct tttgctttag ctagttttaa atcagcattt ctataatcaa
    60901 acttttccaa atcattaaga gcatgtttaa tttctgttct agcctcacct gcacgaagta
    60961 ttatttgcat tgccacctct actaattctt catctattat atgttcttca attgtcatat
    61021 ttataatttc ctttcaattt ctaaatttaa acctcttggc tctctaattt tatctcttct
    61081 ttctcataag ctttaaaaaa tggataccat atcataaata gcaatactat atttattgct
    61141 aaaacaataa gacctctaac atcttgattt accataaaag tagatatacc aaaaggaaca
    61201 taccataaat taaacacctt actcggaatt gtcacaaatc ccatactcat tgataagtaa
    61261 gtagttattg atattactac tgttcctatc cacataggta acattaaaaa tgggttccat
    61321 gccactggag ctccaaatat tactggttca tttatattca ttatagaagg gacaatacat
    61381 gctcttccta ttgcttttat tcttccaact ctggataaac acatcattat aactaatggt
    61441 aatgtagcac ccaaccctcc taaagttatc caacctgttt gaataacttc gtaaacatat
    61501 atattagttg ctactcctcc tgatgctact gctgctgcat tagctgcaat tgcaccaagt
    61561 tgaattgaat aagttatagg agatagtacc cacccactta ttcctaaaga atatataaat
    61621 actactaaga agtttaagag tacaaatcca ggtaatgtct gtgctatatc tgatactggt
    61681 ttaaatactc taactattat ttcaaacatg tcaaagttga gtccataaat taatccccag
    61741 cctacaaaca ttatcactgt tataggtaac atattatcaa accacttgct tacaaaatcc
    61801 ggaagtgctg aatcttctcc gaaaaatgaa aaagaaccaa ataaagacat tattaatcca
    61861 gagaataatc ctgcaactag cgatacaagc attccttctc ctccaaacct gttgaagtta
    61921 aatatagctc cttcattcgt aatctctgga cgaatcatca ttaacattaa tccagcacct
    61981 gcaagaccag ctactacact catactttca aatttcttat tcttcattat ttccataggc
    62041 aataaaaatg ctataaataa tcctaaaagt ccaaatgtat attgatttat tggacttaaa
    62101 tcaggtaaaa agcttatgta attcttcaag acagaaacta tagttactaa tgagcctaca
    62161 aataccattg gcaaaacttt cattatagtt gattgaactg attgtaccca tatattctta
    62221 gtcatattat ttacaacagg agtaaatttt tcacttaaaa aatctataaa tttattcata
    62281 aacactctcc ccataaatat tttatttgtt tgatattagt tctagtgctt cttccaaagc
    62341 ctttgcccca tctagtcttc catatgcagt tttagatata catgctactg gaacattata
    62401 ttcattagcc ttttgttgaa tttcttcctt catataatct aaatgtggtc ctagtaataa
    62461 acaatctatt tctgataaat acttatctat ctctgactca cttctcgctt ttatatctgc
    62521 ttctataccc tttttctttg cactctttct catactagtt gccataaaac ctgtacttgc
    62581 tcctgaacca cacgccaaaa gcactcttat atttttcata atgatacctc caatattttt
    62641 atccattaat ttatttctta atgaactttt tattttatta tgtttatatt gtacttacca
    62701 aataagttca tttcacataa atatatttcc taataatagg aaatcaatta ctcttaatta
    62761 aacatattaa tatagtataa tgtatcttat aatacgtaca ttcaattata taattatcat
    62821 atcatccaga ttttatttta aaactatgcg agggaatcta atgaaaacat ctaaaaaaga
    62881 actattttta aatttcataa aaacacaaca tgattggata gattcatcta cattggctaa
    62941 ttatcttaat gtctcaacgc gttcaattag aaaatatgta aacgaaatta attccaatgg
    63001 tgaatttata ttatcctcta aaaaaggata taaagtaaat ctcaataata attgtcaaac
    63061 caaggttgat agttcagaaa atatatcacc tgataacagg ttaaatttaa ttttaaaaga
    63121 acttatagtt aatagtaatg gaattaatat atttgatttg agtgaagact tgtttgttag
    63181 tccagctact attgaaggag atatagtcaa agctaataaa tttataggaa gttataattt
    63241 aaagataaag caatcgaaat ttttattgaa actaattgga aatgagtctg caaagcgcaa
    63301 gttaatgagc tctataatat ttaaagaaac gggaagtgat tttttaagct tatttgatgt
    63361 acaaaaaata tatcaagagt ataatttgac taaactaaaa gaaaatataa tgtatatatt
    63421 aaaaaaatac aatttattta taaatgagta tgctataaac aacatacttc ttcatttaat
    63481 gataactata gacagaataa aaaagaataa ttacatagac tctgttgaag tagtaaacta
    63541 cataaacaat aacgtagata taaatattgc aaaagacata tcaaattttt tagaatctga
    63601 atacaatata actttaacta gtgcggaatt atactattta gtatttcagt taacaaacaa
    63661 aactacagtc ttaaactaca atcaaatgga tactaaatca ttgtcaaatt atatagatga
    63721 acactttgtt aaattaacta aaaaaataat taaaaatgta tatgacttat atcttataga
    63781 tttatctgat gaggaatttg ttgtaaaatt tactcttcat gtaaaaaatt taatcagtag
    63841 agccaaaaat aatcaagttt taagaaatca aatacctcaa aagttaaaag attcctaccc
    63901 tttgatatat gatatatctg tttatatttg caatcagatt caaactttag aaaatgtaga
    63961 tatagacgaa gatgaaatat cttatatatc tcttcatgta ggttcattct ttgatagaca
    64021 aaaattatta gaagataaag ttctatgtgc attaattact ccaaattact atgatttaca
    64081 attcaaaata gtaagagacc ttgagaagag atttaatgaa tccatagaaa ttattcagat
    64141 tttttcagat actcataatc ttgattttga caataaggta gacatggtta ttactacttt
    64201 accaattagc gatagatgcc atataccttt tgtttatgta aatccttacc taaacagaaa
    64261 ggattatgat aatattcaaa gtaaatttat tcagattaaa gatagaaaaa atatacttac
    64321 tgtacaaaat catttagaaa tgtactttag tgaatctttg tttatgaaaa atatatattt
    64381 agatagtgct aaagattata taaaatttat gggaaatatt ctgtacgaaa ataaatatgt
    64441 caaacccaat tatatagatg atgttcttat aagagaaaaa atgtcttcaa ctgcatttaa
    64501 taacaatgta gcaattcctc atagcatgaa aatggatgct ttaaaaaccg gagtatgttt
    64561 aattgttaac gataaaccag ttaaatgggg tgaggaaaaa gttcagatta tagctatgat
    64621 acctataaat gaaaaagaaa aagaaaaatt caattacata tttgaaagct ttattgaaat
    64681 attatctgag tggaataatg ttaaagaact tactaaggca gataactata gtagttttat
    64741 gaatagaata gcttatctta ttcaaaatat ctaaatccat taatttattt ccaatatatg
    64801 tttcttaagt tattaacata aaatagataa gctgtcacac taaaaagtct aaattaatat
    64861 gtgacagctt tttacctaat ataccttgtt ttaatactac atattttttg actgttgtat
    64921 actagttata agattgaata tttgtgttgt tgtagctgtc atattctcac tagcagttgc
    64981 tttatccatt gcttcttcta ttgtcatagc tctatttact atagaaaaat aagcatctat
    65041 accctcttca ttacatttaa ctgcatcttc tgttgtggct ccagccaaac ctattacttt
    65101 taccccatat ttttttgcca gttttgcaac tcctattgga gccttgccca tagcagtttg
    65161 attgtccaat ctaccttcac cagttatgac aaaatctgca tcttttaact cttcctctaa
    65221 tttaatttct tctaatatta tttttattcc agattctaat tttgaattta aaaatgctaa
    65281 aaaagcaaaa cctaatcctc ctgctgctcc tgctccttct acattagcta catctttact
    65341 taagtaattt ttaactactt tagaaaaatt tctaagccca ttatctaact cctcaattat
    65401 ttctgatgtt gcaccttttt gagacccgta tatgtatgca gctccatttt tcccaaacag
    65461 cggattattt acatcacagg ctattttaaa cttacattca tctaattcct ttaatctatt
    65521 ttctattttt atatgtctta tttcatttaa aacttttcca cctaatccta ctaacttgtt
    65581 atttttatca taaaactcaa accctaaggc ttgaagcata cctatcccag catcattagt
    65641 agcacttcca cctatcccaa ctataaaatt tctatagcct ttatttattg cttcctttat
    65701 tatttcccca acaccataag ttgtagtgta taaaggattt ctaagttcag tcggaaccaa
    65761 tgttaatcct gatgcttgag ctatttctat tattgctgta cttgtatttt ttaataatcc
    65821 atatgttgca tccacttttt tagctattgg tccagtaact tctatagtct cttttttacc
    65881 attcatccct tgaactaaag catctactgt cccttcacca ccatcagcaa gtggcaatat
    65941 ctttacttgc gcatcttctt taaccttcaa tatccccttt tttattgcat ttcctgcctc
    66001 tattgaagat aagcttcctt tcaaagaatc tatagaaatt aatattttca tatttatcta
    66061 ctccttttta ttactcctta ttttaaacat ataattttat gagcttaatt tatcttttat
    66121 tttatactct atatctctct ttgtatacaa cttataccat taatattctt ttatcttata
    66181 aaaagggagt gtctcaaaat aaatttctta gttcatgaga cactcttttt gtataaaatc
    66241 aaatatatgt ttattatttc aacaatgata aggaggatta tctctatttt aagataattc
    66301 ctttttagca ctatctaatc atttttagca ctatttaacc aatatagttt taacttggtt
    66361 cattaagcac tctacattta cagagttatt atctattgat atagattcta attctttttc
    66421 atttaggtta atccatttag ctgttttaat atttttgtta aatactatgt tagctgattt
    66481 tgtttcttct ttagaattat aaaatctaac tactaatgcc tcttgttttt cagccttttt
    66541 tacaacactt aacacaagat ccttattagt ttccttaagt aaactatatg aataatctac
    66601 ttctatttct gattgattca atttcatagc attatatggc attttattat aagtttgtat
    66661 ttttgttaaa tactctttag ccatatttgc aacatttgct tctagtgtag atttttcatg
    66721 agtaactatt gctaagtcta tttttatatc tcctatcatt tgagaatctg gagtaggcaa
    66781 ctttattcct gatggacgac ctgggcgtct tgccatttct tctttaccta ggaatcctac
    66841 acttctaaat aatgttatag ctattgtgtc aaatttttcc cctactattt caaactctct
    66901 tgtactgttt gtaagaacag ctactccatg ctctttgtca gacaatccaa cgaatgttag
    66961 cattggatat atagaatctg gtctttcact ccattcttcc tgttgccaaa cttccatagc
    67021 atcatcatac acacttctct ttatatatcc aaactgatta tcagacacag aaaactttga
    67081 agctatattt gttggtatat aagttctaac cctacaatct cttgcttggt tatttatgtt
    67141 gaatactaca tctattatag ctttatcatt tggaacattt ataactatat caaagtcaat
    67201 aaatgaatct gctctattat tttttctagc ttgtatatct tttggtactt ttaatctata
    67261 atttatcttt atctcattat taaatctatt tttctttata gtggaatttg ctactatatt
    67321 atcgttaaat attaatttct catttagaag tggtgaaaaa tcatactcat ctccttcatc
    67381 tcctccattt tccatcaata atacattttc aaaagtttta tttaattttt tatcaaatat
    67441 ctttaatgtc ccgttttcat taacttgaat agtataaaag tcattatcta ccatgtcaca
    67501 tacttcataa gctttttcta acatatgttc aacttctttt atcatatacg ccttataccc
    67561 cattgcaggt attttatctt taaagtttat tgtatatacc ataaatgaat catagtttcc
    67621 ataatgaaca atttgacggt ctattaatcc tgcatctatt acttctttat gtaccacttc
    67681 aaaatccaac ttattattat ctttatcaaa tatttcaaat gctttcattt tagttataac
    67741 ttgggcgctc actatttcat tcctatcgta aggcattaag ttaaatgcta ctaacttatc
    67801 taaagccatt tcacaactca ttgcatcaac tattcttctt ttgtaaaatg ttattaattg
    67861 gtctactttt tcctcagcta agaaaaatct attcattatt tcctggtgaa ctttatctga
    67921 acaacaacat ccaatgctgt catgagcatg atttttcatt atttctttcc aaattaactc
    67981 tattaatcca tgatgatatt caaatcctag agaatatgca atagaagcta gtggctccaa
    68041 tatgttggtt atctttgatt ctattctagc atttgctgat tttatatcca ttcttgttga
    68101 gaatatactt ctatgaaccc tcatatattt cccatctaaa aattcccctt ttattgtatc
    68161 tatatcctca tttttttcta gctctttaaa tatgttttca tatctactta agaaaaattt
    68221 tctttctgga taacattctt ttaatttata tataacttca aatatattct tttgaattgg
    68281 catttggtca tgtccatttg gaagtattat atggtcagta gttgcaccct tatcaagaac
    68341 cggtaaatat ttatccattc ttgttcttag ctcatcttca ttcattggta gatattttcc
    68401 tattgcataa cctaatggaa gtatttgaac caaaacagaa gacccatcat cactcttcca
    68461 attaaactct gttttattag ttccttttct ttcagaacat cctctccaaa acattgagta
    68521 ttttatatca aacccattta gtatttgtgg catttgagca ctttgaccaa atgaatctgg
    68581 taaatatcct attttcatat attctccaaa ttcatcacaa tcttttattc catatagtaa
    68641 atttctaagt atggattctc caccaactac catttcatca gtttgagtat accaaggacc
    68701 tattattagc cttccttctt gaactaattt ttttattctc tccttacatt caggcttaac
    68761 tgctaaataa tcttctaata tagcagtttg accatccatc acataatatg gatagttatg
    68821 attattttct aacatatcca ttatttcttc catattattt acaagtaata ttctagattc
    68881 ctcagttgag aagtaccatt ctctatccca atgcatatga ggaactatgt gtacattttt
    68941 tttcattgct tatcctccaa aacttatctg ataatatttt ctgtctaatt aaaaatccaa
    69001 taaaaatact actgagttta caaaattttt taatatttat tttatcacta taattaaacc
    69061 tttgatttaa atatctaata acgtatcttt taatgtatct ttctttgatt tttttgtttc
    69121 ctagttatta ttaataatat tgctgatatt atagctccaa gtactgccgc aaagaaccat
    69181 attgatgcta taataaatcc tgacatactt ccctctaaaa gcgccaatga gaatatcccc
    69241 gctccaggca cttgaagacc tatattgaag aatgctacta tagacccagt tatggctgaa
    69301 ccagctacca atgatggtat aacacggatt gggtcctcta tcataaatgg tattgcacct
    69361 tcagttattc cagccaatcc taatatccaa gtttgctttc ctatttcctt ttctgattct
    69421 gaaaataaat ctctgcctaa aacagtagct attgtaactc caaaagctga aaccatctta
    69481 actgatgcaa atattgcata aggtataaaa tttccacttg ctattgctcc tattgcaaat
    69541 gtataggctg ctttatttat tggtccacct aagtcaaatg aaaccatagc tcctattatt
    69601 gcacctagta gtattgcatt tactccagtc atcccattta accaatttat aagaccattg
    69661 ttaagtgctg ctacaggctt tcctactaca aataacatca ataaacctac taccaaagaa
    69721 ccaactactg gatataccca aaaacttacg aatccagcta atgtgccttt ggctggtata
    69781 ttcttcttta aaaattttac tatataacca gcaagtaaac ctcctaacat acctccaaga
    69841 aatccactac ctattaaatc agctgctaga cctgctgcaa atcctggtcc aagacctggt
    69901 ttttcagcta gtgagtaaga catatatgct gataatactg gaaccatcaa tgtacctaac
    69961 atacctccag aaagctttct taattgccat aaccaagaac cttcttgatt gtatagttct
    70021 tgtagaccaa atgcttgaga tgctaatact gcaaatgcaa gtatcatacc tcctgccaca
    70081 ataagtggta ttatatgaga tactcctgta agtattgctg attttacatc ttttttccat
    70141 gatgattttt cacaatatga tatatcagat gatttttcta tataatcacc tttaccttgt
    70201 ttttgtgcta cttctaaagc ttcgtatatt atttcttttg ctctttttag tggagctgat
    70261 actgacgttt ttatgtttgg caaatgttca aatctttctg tatttttagg tgctacatct
    70321 gttgcatata ttattgcatc tgcccttttt attatatctg gtgtatgagg gtccaccata
    70381 ccattagctc cttgcttttc tacatacaca tccacaccta tttctttacc agctttaatt
    70441 aatgcttctg ctgacatata tgtatgtgct atacctgcag ggcatgctgt tatcgctaat
    70501 ataatttttt ttgattcatt ttgaatccta atctcttctt ttatttgttc tttcttttct
    70561 tttatatcta agttattaaa taactctttc ttagtttttg aatttaacaa catattcata
    70621 taatcttcat ttgacagtct agtaactaac tcagaaagta tttgtatgtg tgtatttcca
    70681 ccttcatttt ctggtactgc tattaaaaat attatctcta ctttattatc tgggtctacg
    70741 ctttcccaat tttctattgg tgtctctaag gtcatagctg caaatgaagc ttctttaact
    70801 gacttagatt ttccatgagg aattgcaagc cctctttcaa aacctgttgg agataaagtt
    70861 tctctgtaca ttacagcttc taaatattcc tcataagatg ttaacttgcc ttcatcatat
    70921 agctttcttg ctaagaactt tattgcgtct tcctttgttt ttattttttg ttttaaaaaa
    70981 acaaggtttt catttgtgat tttcttaaat tccaaaatta cgccctcctt aaatcattta
    71041 atgttatgaa tatagcataa aataaatcat gaaaatgttt ttttgaaatt atacacacaa
    71101 tttcttctta aaaaataaag atttgtgtat ttatacacaa atctctatct taaccagtat
    71161 tgttctatta ttgctctcat aatcatcata attggaacct tatctgatat attgtaccca
    71221 tttacttgtt taattgttga atagcaatat aaacttatat ctgcaatttg ttgcaattga
    71281 ttttcacata tatgtgttag agctactacc ttacaaccct tattaattgc tgtctttgct
    71341 gcttctataa cttctttcgt ttctccactt aaactaagtg caaaaaacat atcttgttca
    71401 cctaattttc ctatatcatg aagtacttca tgtctttgac tatagtaagt tatattatca
    71461 tgcccacctc taatttcttt tactaatatc tcacataaag gaatgttttg acctattcca
    71521 taaactataa tactcctaga tttttgaatt atatctgcta ctttatttat tttttcataa
    71581 tctattagct ctaatgtctt ttttatatct gattcaaaac cattttttgg ctctttatcc
    71641 tcatttttta actcttcttt taaattattt tttagttgag agaaaccatc atactccatt
    71701 tttttacata gcctaactat ggtatttggg acagtaaaaa atttatctgc taaagattgt
    71761 attgataatt ttactatttc ttctttgttt tttctcatat attcaattat catgtcttct
    71821 gtatctgtaa atttatactc atattttttt gctctttcat aaaattccat agtttatcct
    71881 ccatctattt tattattcat aagtaaaatt caaaaatatt agctaaaatt ttcgttaata
    71941 taattataat ttaatatttt taatttatta atgcatacta ctctttttat tatacataaa
    72001 aaatgtgtac ttcctatatt gatagagatg attcaagttt ttattttgat acatctctat
    72061 caatattttt ttagaaaata cacatttttt tcaaatactt atttttaatt aaaactttag
    72121 gtaatctatt ctttatatat aattattaga cttgaaaata tctttaaaat caaccaattc
    72181 aatattattt ctttttaacc acattttaac ttccttatca catagcattg catgttcata
    72241 tactctctct tgaataagag aagatgattt tataagacta taatctataa atcctggatg
    72301 agtaaccatc aatgttatat ctttatctaa atttatatat ttttcttcaa ataatttaac
    72361 aaaagattta tttaacttgt aaaaatcatt ctgaggatat ttacttggca tgctaataca
    72421 tgaatctaaa taatagggac aacttggtat accgtattct tttgcagcat cacacattgc
    72481 tgatattgat acattttctt ctataccatg tatatcaata tactcaggca atttactcat
    72541 atacaacttg taagtttcaa tttgagcaca aacttcttca tatacttctt cataattaaa
    72601 aacctcttta cctgtcagta gttgcgttct tcttattttg ctagaaacaa attttccacc
    72661 ttcatctaac aaattcttta tcttaatatg ttctttgcaa caaggttctc ctattactaa
    72721 attaacatgt aaaccaaaac atacatcatc attttttacc atttctatag cttgtcttga
    72781 aaaaggcata ttcaccatga ttccagcact tgtaacaata ccgttcttat aagaagatat
    72841 tatccctagt gtaacacctt ctgaatatcc tatatcatct gccctaacta ctaatttctt
    72901 cattttatgc atctgcctgc tttctcaact catcaagttg catttccatc tcatccttta
    72961 ctttaacaac atccgttcct atgatgattt gaactgatgt attactcaat ttaattaccc
    73021 ctttggctcc tgttttttta atattatcat cattcaaaat agtggcatcc ttcacttcta
    73081 aacgtaatct cgtcatacaa ttattaagag tcactatatt ttcataacca ccacaatttt
    73141 taattatctg tttagccata tatgaaaaat taccatgaga aagttttaaa ttcttttctt
    73201 tttcactaac tttatcacct atctctatct caacttcacg tcctggtgtt tgtacattat
    73261 cttttattat tatatattta aatgttacat aatataatac aaagaataca actcctacag
    73321 gtataactaa ccacgcttta tctccataac taaaacttaa gacatagtca attatacttg
    73381 ctccattaaa tgaacccaag cgagcaccca gtaaatatag tacaactcca cctagaccag
    73441 aataaaaaga atgaattata tataactttg gagatgcaaa taaaaacgaa aattctattg
    73501 gttcagttac tgttgccata aaagaagtca atgctccagc ggtcattgca ccttttactt
    73561 cttgcttctt tttatcttgt gctgttttat atatagcata agaaatagca ggtattgaaa
    73621 acatcataat tatgtaaaat cctgtccaga agaatcctgc atttgggtct cctgccataa
    73681 atctaggaat ttctcctctt ataacttctc ctgttgatgt tgtatattca cccatttcaa
    73741 ataatatgta agcatttaaa acttgatgta acccagttgg tattagtgca cggttacaga
    73801 ataaaaacaa gaatattcct attgcaccag ctcctcccaa ccaaaaacca aattgattca
    73861 ttgcagcttg tggatatatc cataataaac taaatatata tgataaaatt aaagcaacca
    73921 ctggtgatag tgtaattaca catttttctc ctgcaaagaa gcttaaaaat gctggaactt
    73981 taactttata tgttttattg taagtccatg ctatacaagc tccaacaatt atcccaccaa
    74041 atacacctgc atttaatgta tcattcaata actctaaatt tgacttaaat atcatatatg
    74101 caactacggc tgcaaccatt acacttgtct tgtctttaga ctttgagtag gcactagctg
    74161 ctcctaacaa aaataagtag tccacatttg aaaatactat attagatata ttagatatag
    74221 ctggcacatt gagcatattt ggaccaaata ataatcctaa tatacctgct gctggcatta
    74281 cagctattgg caccagcata gtctttccta aaagtgacag ttgttgcatc attttgttta
    74341 agaacctctt catatccaat cccctttcta tttcggttta attttttgtg aaaacgattt
    74401 attcacattt tatattttaa atattatatt tgtttaaaca aattgtcaat attttttatt
    74461 cattttattt ttatcattta gtttcacata taaatccttt taagtatatt gctatatcta
    74521 gtctattttt ttaattcatt ttttttattt taaaaatatg tttaaccatg tatttgaaac
    74581 aacccacaaa ataattctat tttatccttt ttatggttga tatgattcta ttttcactat
    74641 acatgtctaa acacatttga tataatttgt tcatatcagt tcaataatat tactaaagac
    74701 ctttaaggag ggataggggt atatggctaa aaataaattt tcagagatat atgaagtatt
    74761 gaaagaggaa atacttgatg gtaaatatac aagtaatatg atgctgccta ctgaacttca
    74821 acttattgaa aggttttcat gtagcagaaa cactgtacgt agagcaattt ctcaattaaa
    74881 cacagaagga tatgttcaaa gtataaaagg caagggtgtt gtagtgttag aaaatagttg
    74941 ttctaatgat ttttttctaa atatgcacaa tttcaaaggt gtagaatcga ttgtagaaga
    75001 taaaaaggtt aatactgcta ctagtgttct ccacttcagc aaaatcttaa ttgataataa
    75061 gttatctaaa aagacaggtt ttaaagctgg tagtgaagta tattaccttc acagactaag
    75121 atatattgat aacataccta aaattctcga cattaactat tttctatgta gtatagttaa
    75181 agaccttgat gtttctatag cacaaggctc tatttataaa tatatagaag agtgtctagg
    75241 tacaaaaatt gtttcatcca gaaagatatt taaaattgaa aaagctacag agcttgagtt
    75301 aaaaacgcta cctctaaatg attataattg tgttggtgtt attaaaaata gtgtatatac
    75361 tgatgatgga aagctttttg aatatactga atcaaagcat acacctgaaa catttgtatt
    75421 catggatgtt actcaaagat attaaaagag gatgtctcaa aataaatatt tgaatcatct
    75481 ttttttattt taccaaatta aaattattca ttttagaaat caatttttta tcaattgaaa
    75541 aatagatagg aacaaattgt ccctatctat ttttaatagt ttatttttta aactatttgt
    75601 tgttaaagta taaatagtct atactctgtt taaatctttc aagacctttt tttaattttt
    75661 ctcttggaca gccacaattt aatcttaaat atttctcact tccatatact tctccccgca
    75721 ttattcccac tcccccaata ttaattaaag aatcttgtat ttcttcacaa gtaaatggaa
    75781 cgtctctaca atctatccat gccaaataag taccttctgg ctttgtaaat ttaatatctt
    75841 caaaattctc ttttataaac tgtgatacat aacttaagtt attatctatg tattcgacga
    75901 gttgttctat ataataatca cattcattat aagaaaccat tgtcgcatac atacctggta
    75961 aacttacaga gtttagaaaa tctcttcttc ttgttattga taaaaattca tcatatatat
    76021 ttttatttgc tataacagca tatgaaccta ttaatcctgg ataattaaat gttttacttc
    76081 cagaagacac taaatatagc tctttatatt cccttaaata tttaactatt ggcaaatgtt
    76141 tattatctgg catgattata tcagcatgta tttcatcact tataattttt atattgtatt
    76201 ttttacaagt atttattaaa aactctaatt caacttcttt ccaaacctta cctgttggat
    76261 tatgaggtga gcataataat aatacatcac aattttttac actatcttca aattcgtcaa
    76321 aatctatatt aaatttacca tccttttcat ataattgtat tttttctaac tcaaatccat
    76381 tttcttctat tacactgaaa aatgcatcat acatagggtt aaatgtagca actttctttt
    76441 tattattaca aagtaatcta agtagtaatg ctactgaata cataactgat ggactatata
    76501 acacccaatc gctctctatt ttcgcttcaa atcgtctatt ataatagcct gtaatacttc
    76561 ctttaaaatc attgtgattc catctagaat atccatatat ctgatgctgt aatatctcct
    76621 gtaacttttc atatactggt ttaggtactg taaaatctgt atctgaaata gaaaatggaa
    76681 tcaaatcttt tttaccaaat ctatcttgta tataatccca ctgtgtacaa taagtacctt
    76741 tgcggttata aacttcatca aaattgtgct tcatattaat cctccaatat aattcttctc
    76801 acatgcaata taaaaatacg atttattaga tttttatgga gtattttttg cttcatttgc
    76861 atgtttttta tctaaaataa aatattaatt atattttgtt actaaaatat ctttctactc
    76921 tataaaataa aagctatgaa tatagatttg taactctatc tccacagctt ttatttacat
    76981 gcttgattat atttctagaa atctaaatca cctaataagc ctaaatcttc tggagatatt
    77041 acagattctt cttgaatttc ttgaacctgc ttagtatctc tctcatcaca ctgtttttca
    77101 tacattttat agaatggata ccatattaat atagaaccca ccatttgaaa tgcttgaact
    77161 attggagtta accaatgtcc atttactaag aatccttcta taaatactcc taaatatgga
    77221 gggttgaaaa agggtttggc taatattcct gcattcatta aaaatgcagg gaatgttccc
    77281 agtatagttc ctccaattac aaaaggtaaa aagaatgttg ggtttaaaac tatcggacca
    77341 ccaaataata taggttcatt tataccaaat aatgctggta ctaaagaaac ttgacctata
    77401 cgcttgaaat ctactctttt agacattaag taccaaaata ccaagccaaa tgttactcct
    77461 gtacctgtaa aatttgcaaa tgcacttacc attcctcctg tataaaagtg tggtaatgat
    77521 tgacctactg ccatagcctc caagttttca gctaaaaatt gagctgttat tggtgctgtt
    77581 attggcgata atacagatgg atgtattcca aaaaagaata atgttattcc taggaatgtt
    77641 ataaatgcaa atgtaaatgg attatctaaa gaaccaacta atggagctaa aaattgggta
    77701 agtatttctg gaggaagtac tccaaatact tgtaaagtta ttattcttat acctataaat
    77761 actccaacta ttattactgt tgtaggtatt aattcaaatg aacttgatac aaaatcgggt
    77821 acactttctg gcatacgtat agtaaagttt ttctttttac accatctata caactcaaca
    77881 gctaatacac ctgccaccat tgctataaat aaccctttag ttcccatata cttaatatcc
    77941 attccaccat cttcagtgaa attaaaactc attaaaagaa aaccaacagc agctaaggac
    78001 attgctcctg gtacataaag cttatagtgt tctgaaagga aatacgttat acacatacat
    78061 actaaaaatc ccatcattcc tatagttaag taaaatggaa tttgtaatga atccatatta
    78121 tttgttataa atgaagttat agcatttgct cctatagctt tttctgttaa gtttcctata
    78181 gcctctggca taagacttaa acttcctatt ataaggattg gagtcatcgc caccattgac
    78241 tttttaattg cacttaagtg atgctgtttg tccattcttt gtgcaatagg tgtaagatgc
    78301 ttattcataa attgttcgaa ctttttaaac attatttttc ccccatcatc atagtatact
    78361 ttaatgaata ttacatatta gcttttttgt gagctattaa tgccatctta agtgcagttg
    78421 caccatccat ttttccatat gtattttgat ctattattac atatggtaca tttttaggct
    78481 ctagtatagg ttttatgtaa tcaagtttat gagctatttg tggtcctata actagtacat
    78541 cacaattatc aacctcattt tttaataaat ctactggtat tgctttaaat tcaaaatcat
    78601 catcatttaa ttttttacta ttttttacaa cattctccat atttttcatt agcattgtag
    78661 tcgaaaatcc acctgcacaa cataatatta ttctcatttt tacgcctcct tagattcaaa
    78721 tatatctatt aatttttcta ttaaatctct agataactgt gaagtcatgt aatgatcttg
    78781 ggcatgtacc attaataaac tcaccattga cttactttca caatctccag ataattcact
    78841 ttgtattaat gcagtttgtg cattatgagc ttctatatct atttttctag cttcttctat
    78901 acaagctcta gctccttcat aatcgccttc tttcacttta tttaaagctt caaatgactt
    78961 tgatttacta tcccctgaag aaactattat ctccattatt ttcatctcta aattttccat
    79021 gcttacctcc tatgtcgtta aataaacttt aatatgttat tgtacttctc catattcata
    79081 tcattaataa cagcagtaca taaattgata acctcttcaa catctctcat atctaccatt
    79141 gaataatttc catgacagta tcttaaagga acccccaaaa ctatagctaa ttttccttca
    79201 tttactagat gtgcatttcc agcatctgtt cctccaccac taaacatatc gcattggaat
    79261 tttatatcat acttagttgc taagtctttc atataattta aaaatttttt attaggaatc
    79321 attgttttat cataatgcac tatcatacaa cctttagata attggcgttg attggtataa
    79381 tttctaatta aatctggtgc acaagcaaca tctacagcaa acactatatc aggattcact
    79441 acttttgatg ttgttttacc tcctcttatt ccaacttctt cagaacttgt atatacaata
    79501 tatatatcat tatcattctt ttttatttga ttaactcttc tatctatctc tttaagtata
    79561 tagcatccta ttctatcatc taaagccttt gccataagta cattttcatt taacatttca
    79621 ctctcactag caaaacatac catatctcct atgtttatac ctaaatcctc aacttcttta
    79681 gctgtactta ctcctatatc tgcatataaa tcttttactt tgttattttc gtcatatgaa
    79741 caatttataa gcccttttac cttagtacca tcaactttac ttatatttac tttttggaaa
    79801 gactttgcac tatctttaac tccaccaaca ttaattaaat gtagcattcc aatatcactt
    79861 atgtgcctta ccataaatcc aacttcatcc atatgagcac aaaacatcat ttttactcca
    79921 ttacctctat ggtgaactat catacttcct aagttatcaa aactaatttc tccatttata
    79981 ttttcagcta atagttctct tatttcttgt tcatttgaag ctattccatc tgcttcacat
    80041 agttttttta aataatctat actcatacga ttaccctcta tattctttga tttattaaag
    80101 ctacaaattc tttgaatgtt ttagcattta caagtagttg aacagtttct atatcattca
    80161 ttatttcata taaactacta ctaatttttt tataaagtcc aatattttct ttttttaaac
    80221 aaatcataaa tattaaagaa acttttttac ctttaaagtc tattggattt tgtaaaattt
    80281 ttactgaaat taaattttca tttccatcaa tatctatagg atgaggtatt gcaactccat
    80341 ttatatatat atttgttgca aagtactctc ttttcaaaac attttcagag tacccataat
    80401 ttcctgcacc ttttaattct atatttttag acatatcttc taaacatttg atataatcaa
    80461 ttgaatcatt gtctatatta aaatagtcat ttcttaaaaa tttgcagata aatgcttgac
    80521 ctttattttc taaagagtat tccttaaatt tttcaaacat aattaactct ttgattctta
    80581 aaatatcata atcatctaaa agttctttta tatatacaat tggtacttct agctttatat
    80641 ctagttcaca aatcgaaaag ataatatctg gattaaattt ttctaattct ttcatctgta
    80701 taagagaaaa agtttttata ttagtatttt caaacaaact gcttatctta aattttatta
    80761 actgagcact tccaccacct gatgaacata ctattgctat tgaattatat tttctaaatt
    80821 tatagatagc ttgcttttcc atattcatag caaaatatgt agctataaac ccaatttcat
    80881 ctcgttggat ttcaacatta tactttttat acattatttt tcctagtaat atagctatat
    80941 taaaagcaac tggatatttg atttgtattt catctataag cggattttga taagatatac
    81001 taaaagtaga cctttctaat aattctgtca aatgatttaa taatgacctt ttaaattctt
    81061 catcttcatt aaaatatgta ttattttctt catcaaattg cttcaaaaaa tcttctaaat
    81121 catctcttaa gttatctgca cctttttgtc ttctaaattt ttttctagct tttttcttta
    81181 tcaaagattt cagtatctta taatcttcac tagataaatt taattcatac tcattggtac
    81241 tatcatctaa ctctaataat ttagattgcc tatctatata catagttact tttaaccaag
    81301 acagtatttc tttcaattca atataattta tgactaaatt attttctttt aatttattga
    81361 taaatttctc ctgaacttct ttaaaatcgt tttccagttt actatcaata tactttttta
    81421 taatttcatt ttcttttata taaagctcta ctatcaattt tcttctttct ttcatactat
    81481 ttataatttt caatccatag tgagattttc tttctagctt aagattgtat ttttttaaat
    81541 aagaatcaat atcttcttta tatcctttta ttactgacct acttgttttt aattcttcta
    81601 atatcctatc tatagttata taatcttcat ttaatataag acatgctatt atactttcaa
    81661 catttaactt aggttggtct aaatactcaa ataactcaac tttaaatttt ttaaataaag
    81721 tattatcttc aatctctaat agataaccta atcctctttt ttgtattatt ttaaaacctt
    81781 tattactaga taccttagat aaatacgaaa aatcattttg tagtgttctt ttagatacag
    81841 aatacttatc tataaaataa gctatagata gatacttatt tgtgttttct aaatcattta
    81901 taatttttaa tattcgcatt cttacacctc ctattatcca taacagtttt atttttacat
    81961 tctaaaaaat attgtagaac tattttattt taattgtaca atctagtatc gatttgtgta
    82021 agatgcttat actgttatta tattttctat acaatacctt taaaaggttt ttaatttcat
    82081 tataaaatga aattaaaaac ctaatacatt acctattatt gaagatattg tgtatatcta
    82141 ctagaattta agtatcatct attatttgca tttaataata caacaagata ttttttaaaa
    82201 taagagttaa ataatagtac aaccttttat tgcatttaaa tattatcaaa acaaaaataa
    82261 atgtactatg ctatttatcc catactaacc tcactattct atatacaatt atatgtttat
    82321 acaaataatt atttattgta tattttagct ttaatattag tttaatgctt gacaatttgt
    82381 ttaaacatat tataattaac ttataaatta caggaggtat caagtatgaa aaattggtgg
    82441 aaaaaagcaa ctgtctatca aatatatcca aaaagtttca aagatagcaa caatgatggt
    82501 ataggtgata taaatggtat tatagaaaaa ttagattatc tgtattcttt aggtgttgat
    82561 ttattatggt tgactcctat gtacgtttct cctcaaagag ataatggata tgatatagaa
    82621 gattattata atatagaccc aaaatatggg acaatgaacg actttgaaaa actcttaaaa
    82681 gaagctcata aaagagacat aaaaataatg atggatatgg tcctaaacca tacatctact
    82741 gaacataaat ggtttaaaga atctaaaaaa agcaaagaca atccatatcg tgattattat
    82801 ttctggaaag atgctaaacc tgatggttct gttcctaata actggatatc cagatttagt
    82861 ggaactgctt ggaaatatga tgaaaccact aaccaatatt atttacattt atttgaagaa
    82921 actcaagctg atttaaattg ggaaaatgaa aaggttcgtg aagaatgtta caaaatacta
    82981 gaattttggg ctgataaagg tattgatggt tttcgtttag atgtagtcaa cctactctcc
    83041 aaaacacctg gattacctga tgaccctata acaggaccaa aaggagatgg aagaactcac
    83101 tacgctgatg gtcctcgtat acacgaatat ttacataata tgaatcaaaa agttttcaaa
    83161 cctaaaaata tagttactgt aggtgaaatg tcatctacta cacctgaaga gtgtatcaac
    83221 tatactagag aaaatcgaga agaactatct atggttttta gcttccatca tatgaaaaca
    83281 gattataaag gaggcgcaaa atggactaat gaaatgttct ctctggataa attaaaaaaa
    83341 gcacaatctg actttcaata taaaatgtat gaaggaaagg gatggaatgc tctattttac
    83401 tctaatcacg accaacctag agctttatct cgatttggag atgatagatt ttttcgtcaa
    83461 gaaagtgcta agatgttagc cataacatta tttggtctac agggtactac atacatatat
    83521 caaggtgaag aaataggtat gacaaatgcc tactttacta aaatagatga atatgatgat
    83581 gctgaaagta agaatgcata ctatcatatg attaaatctg gtattgatga aaaggaggca
    83641 ttgcttatac ttcaacaaaa atccagagat aatgcccgta ctcctatgca atgggataat
    83701 actatttata aggggttttc taatcataaa ccgtggttaa aagttaataa tgacaatatt
    83761 agtgtagaaa atgagcttaa tgattctcgt tcagtatttt atacttatca aagattaatc
    83821 aaatatcgta aacaatatga tatttttaca gaaggtactt atagattgtt agatgaaaat
    83881 cataaaaatc tatttgttta tgaaagagag tataaaaacc aaaatcttct tgttataagt
    83941 aatttcactc atgataatgt agtatataaa ttacctgaaa cttatttgaa taaattaaac
    84001 tacacaatac ttgaaaccaa ttacactaga gatataattg aaaataaaat ggaaataaaa
    84061 ccttacgaaa gtataatgat atattataaa taaagttatt tatgtaaaaa tcggtataac
    84121 accctggtgt tataccaatt ttactaaatt caaagtaata tttatagaat atctatagat
    84181 tagaataatt atttgacgtc tacatcatta tatttctttg aatatacttt agtcatatag
    84241 aaatatatag gaactacaat tatcatccca cctaatcccc aaactatctt cataggttca
    84301 tcaatacctg cttttatcag taataatata cttataataa ctgcaaatat tggtataatt
    84361 gctcctccag gtattctaaa atttacatct ttatcagcat acttctttct caatattagt
    84421 acagctaaac atgtaggaat atattgaata aatctagata caacacttat ttgagataat
    84481 gttgtgaatg aacccgacca tgctattagt aaagttccta tgacagatac tataattgct
    84541 atataaggag ctccattttt attagttttt cttatagact taggcattaa tccttgttca
    84601 accaaagcag cagcagacct tggtgtaaat atggatgatg caatatttat acctccaaca
    84661 gatactatag ttcctattgt aattatatac ccacctatag gacctaacat cttaatggca
    84721 gcatctgcaa caggagtagc tgaccctgcc aagccattac ccaacacccc tatacttatt
    84781 cccagtataa gcatatatat tactgatact acaaacatta ccattaccaa tgctttaggt
    84841 acatttttct tagggttctc catatctttt gctgcaacag ctaaagattc aaatcctgta
    84901 aaagcataaa ataaagttat agatactgct acaaaagctg atgacgcact ttgacctttt
    84961 tgtattatta caaatggggt aaaattagaa ccctttataa agaataatcc tacagctata
    85021 aataaaacta ttggtaataa ttttcctata gtcatgatat tatttaagtg cttagattgt
    85081 ttcattccca taaaatttat aatcccaagt cctacaacta atataccaat tattatattt
    85141 ttaataagtg gttctgctgc ttgtggccat acagatgata gtgttacagc aaagaaattt
    85201 gccatagtag cccaagcaat catactaact atccacttca taaatccaac ttcaaatcca
    85261 acaaaatctc caaatgcctc ttttgcataa agatagggcc ctccatcagt atcaaaccaa
    85321 ctacctgctt cagcaaaaca taaagcaata gaaacagcta aaagcataca aaatactaat
    85381 actaatatac ttgctggacc tatatctgta taagcatcac caggtaaccc gaatatacct
    85441 gaccctatta ttgcattgat tcctaatagt acaatactcc aaaaacctaa cttaatgcat
    85501 ttttccattg ttattccccc caaagccaac ttaatatatt tatatttttt atttagatgc
    85561 ttctttaact attgccataa atattttttt catattatca taatctctag tcatcatttc
    85621 tggatgccat tgtatcccta ttacaaactc acttccttcc ttttctatag cttcaattaa
    85681 accgtcttta gatgtagctg aaacaatata tcccgatgct actttgttga caactaagtg
    85741 atgaaaacta ttaactaaaa cttctttttc tcctaatatt tcatataatt ttgtcccctc
    85801 ctttatctgt actgtatgtg taggtacatt agatagatgt tgctgattgt gtttaatata
    85861 agcaccttca attaaagata aatcttgata caaactacct ccttcagtta catttataat
    85921 ttgttctcct ctacatatac ctaaaactgg ttttttcata tctaaagcat gttttaataa
    85981 tttcatatca aaactatctc tctttggtga tattgccccc aacttattat gaggttcttc
    86041 tttccatatg agtggattta catcttgtcc cccagatagt ataagcgcat ctatattaga
    86101 tacctgctcc tttataatct catcatcata tacaatcggt acaatatatg gtatagcttt
    86161 acacataact actgattgta tataatcatt atttacataa gccctttcat agccaggaaa
    86221 cattcctcct tcatcaatta gtaaattacc tgatattcct attattggat atttcttttt
    86281 aaccaatttc ttcacccctt aacttatttg tgaacaataa aaaatgctac ttctcttaaa
    86341 gagcaagtag cataccaaga ttttatttat ttgaacatta taatttattt tagaaatact
    86401 ttttttgaat acgagtaata taaataactt tatttactta tattttattt taatcctgtt
    86461 tagtttgact tttttaaatt gttttaagta caactaatag gtaaaatagg catttatatt
    86521 ttccttttta tcaacctatt aaatactgtt taatatattt tttccccttc tatttaattc
    86581 acttcccttt ctaccagatt cacatattat caaatccaga tcttttaaca tattaagtat
    86641 tccccttacc tcaccttctg ttatactgta gcctaattca tttattgaat taacaatacc
    86701 atttctacct atatttttat taagattatt ggcatttttt aaacactcca ttactaactt
    86761 tactttctct atagatgttc tatcctttaa tatacttatt tctttactaa aatcttcagt
    86821 tatatttaat aagttatgag gtaaatcatt tattaaaata acatcctcag aactcataat
    86881 gttaatatac atagcagtat tttttaattc tcttatatta cctggccatt catatgcatt
    86941 aataatgtct tgaacatctt gactaattgc tctcttcctt ttcataaaat gctttaacat
    87001 aacttctata tcttcttttc gctctcttaa aggtggtata tttataggca atacatttat
    87061 cctatagtat aaatctgctc taaatctatc tccttttatc atttctaata aatttttatt
    87121 tgtagccgca attactctaa catctatatc tattacattt tctcctccaa ccctcattac
    87181 ttgattctct tgtaatactc taagtaattt gctttgtaag tatataggca tgtctcctat
    87241 ttcatccaaa aatatagttc cattgttagc ctgttcaaat aatccttttt tacctccttt
    87301 taaagctcct gtaaaagcac cttcttcata tccaaaaagt tcactttcaa gtaaattttc
    87361 tggcatagct gcacagttta ttgctataaa tggctgacta tgtcttggtg atgcattatg
    87421 aatagactga gccatgagtt cttttcccgt tccactttct cccgttataa gaattgtata
    87481 atcagattca gctattttca tacctaattt cttagttctt tccatcttcg ttgaaactgt
    87541 ttttatatca tcaaaagtat atctagcaac ttgtcccttt tctctaagct tctttgatag
    87601 gttttgctcc aattttctta tgtaagttat ttcttgaata caaaaataat atccagtaac
    87661 ccttccaaaa ctctctatat tatacttatt tacgtttaag tacttattat taaattttat
    87721 aacttcatca tgtgccttac tcaaactaaa aatcttttta atattctcat tctctaattc
    87781 atctatattt ttccctataa tattactttg aatatctagt atatccccta aactattatt
    87841 gcaaataatt atgtttccct tatctgatac cattgccata cctaagtttg ataaatttat
    87901 tatagaattt aattcatctg cttttatagt aagttctttg tatttagtat ttattcctga
    87961 atataaacta attatttcat ctgtatactt aattagcctc tcagtaattt ctttatcatc
    88021 cagtttgagt tttgctatta tttgaataaa cgttgaacta tcaatatacc tatgacctaa
    88081 atcaataact tcttctatat attttggaac taaacttgac tctcctggcg ttatagctat
    88141 cttaatattt ctatattctt cattgggatt gtatggtata aaattcagat gatttattcc
    88201 tatattgtat aaattagata ttgtttccaa tacagtatgc ttattatcgt ttactactaa
    88261 tacatctatt ccttctggca atgaaaataa cttatatata tccttttgct ttatgctcct
    88321 atttatagtt attatctttg agacatcttc tacatatttt tttattttta atactctatc
    88381 atctatcatt accaatatta tgtcatcttt tattaattcc ttctctgtta ttttatttaa
    88441 ataataattt tttatcatta ctttatcttt aaatatcatt tctagatttt tatttaagaa
    88501 acattctaat ttagacaacc catcagttac tactgctatt gttttcattt gattactcct
    88561 tttaaaatat actctactct tttataatat acatctgatt ttcactttaa tagcacaaaa
    88621 aattgtacat ttagtatact aacatattcc tttattagtt ttatgtccct aaatatcata
    88681 gttgcaatat ctatcatatt tcttaaactt ctataaagca aaaattgtgc caaattaata
    88741 attttcttaa ttttattcta aagttcctca atagtattta cagacttagc acttatagct
    88801 tataagtctt tatattatta atctattttt ataggttaat tgtacaaatc atatatcact
    88861 tttacctatt aaatgcatta taaaaaagat ggaataacga ttcgtcactc cacctttttt
    88921 gtaataaaaa attgtatata taaacactat ttactactct tctaagtaca aacagtatct
    88981 acatactata acctttcacc attagattct attacttgtt tataccagtc aaaactcttt
    89041 ttcttaatcc tagacaagtc tccacttcca tcatcatact tatccacgta tataaaccca
    89101 tatctcttgg ccatctcacc agtagatgca cttactaaat ctatacatcc ccatggagta
    89161 tatccaaata aatcaacacc atcttctaca gcttccttca tttgctctat atgtgctttt
    89221 aaatactcta tacgatagtc atcatttatc actccattag attctttttt atcataagct
    89281 cctaaaccat tttcaactac catcataggt attctatatc tatcataaat ttcatttagt
    89341 gcatatctaa gcccttcagg gtctatttgc catccccatt cactagactt aagatatgga
    89401 tttttcactc cacctaatat gttgccactt gtattatctt ctttagaatc actacttaca
    89461 catgtagaca tatagtaact aaatgtataa aaatctacac aaccttcttt taaaatttct
    89521 aaatctcctt tttccatttt tatttcaata ttattttctc caaaatatct attcatataa
    89581 gttggatatt cgccacgcac ttgtacatct ccacagaaat aattcattac tctactatct
    89641 ctttgagttt taactgcatc atctggatta caagtataag gatacattgt tgcaaatatt
    89701 tgcatacatc caacttgata atttgaatct atttcatgag ctaacttaac agccttagca
    89761 cttgctacaa attgatgatg taacccttga aaacgaagtt gaggtatatc tacttggttt
    89821 ataaaatctg tagtcccttc atttaatatt ccttgtgata agtagcctcc cataggcatt
    89881 gtagctgaat ttatttcatt aaatgtcagc caatatttta cttttccttt atatctttta
    89941 aatattgttt cacagtaatt catatacaag tctattacat ctcttgaaac ccatccattg
    90001 tatttctctg ttattgcaaa tggtatttca tagtgagata ttgttattaa tggttctata
    90061 ttatatttta aacattcatc tatcacattt tcataaaatt taagtcctgc ttcatttggt
    90121 tctttctcca ttccagttgg aaatattcta gtccatgcta ttgaaaatct aaatacctta
    90181 aatcccattt ctgcaaataa agctatatct tctttgtatc tgtgataaaa atctattgct
    90241 tcatgacttg gataaaatgt tcctttttct ataactctcg ttattctttt acttactttt
    90301 tgagaacctc cagtacacat atctgaacaa gaaggacctt tcccatctaa attccatgct
    90361 ccttcacatt gatttgctgc tgttgctcca ccccataaaa aatctttttt aaatgacata
    90421 cctatatcct cctattataa ttcttcacca tttgattcta ttactttttt ataccaggca
    90481 aaactcttct ttttactgcg ttttaaagtt ccatttccat cattatcttt atccacatat
    90541 ataaatccat agcgcttctt catttctcca gtacttgcac ttactaagtc aatacatccc
    90601 catggtgtgt acccccataa atcaacacca tctaactcaa cagcatctat catggctttt
    90661 atatgagcac gtaaataatc aattctataa tcatcattta tatttccatt ttcatctgga
    90721 ttatctactg ctcctagtcc attttcaact ataaataatg gtttttgata acggtcatat
    90781 aaagagttca tagttattct aagccctaat gggtctattt gccatcccca ctcacttgca
    90841 tctagatatg gatttttaag acttgcaaaa acatttcctt ctgttaaaat atttactttt
    90901 gggtctgcac ttgtaagtct tgatgagtaa tatgagaacg aaataaaatc tactgtgttc
    90961 tctttaagta tctttttatc atcttcttcc atcactatat ttattccttt tctctccaat
    91021 tcttttaatg catatgttgg atattctcca cgagattgta catctataaa aaagtaattt
    91081 tccctatctt tttctataga tttccataca tctagtgggt tacaagtatt aggataagta
    91141 tttcctgctg ctaacataca ccctatttta aattcttgat ttatgttatg tgctagttta
    91201 gtaactaacg cactcgcaac taattgatga tgtgcagctt ggtattttat ttgttcttca
    91261 ttttctccct cttcaatata gaggcctgca cctataaatg gtaaatgaag tatcatgttt
    91321 atttcattaa atgttagcca atactttacc ttacctttaa accttgtaaa aataacttca
    91381 cagtatttta catataagtc tactagctta cgatttctcc atgctccata tttttttacc
    91441 aaatacatgg gaacatcaaa atgacagatt gttactactg gttctattcc atactttaaa
    91501 cactcatcaa ataaatcttc atagaatttt agtccctctt catttggaac atcctcaact
    91561 cctgttggaa atatcctagt ccatgctatt gacatacgat agcatttaaa tcccatctca
    91621 gcaaataatt ttatatcttc tttataattg tgatacatat ctattgcttc atgagctggg
    91681 taatagtgtt catcatcaca ttcaaacatt ttcattttcc cagccaaaac tggaaatcta
    91741 tcttttcctt gtggtgtaac gtcaacatta gctagacctc taccatcttc tttatatcca
    91801 ccttcacatt ggtttgctgc tgttgctcca ccccataaaa aatcttttct aagtgccata
    91861 attctacctc caataattta tttatagtaa ctttatttta aaataaaaat acatatatat
    91921 aattcttaat taatagaact ctcttttacg ctaaaacagt tatcaattcc tgactattat
    91981 ttacatgctt ttgtgtattt tctacaatat ccacataatc agaataatta gtaacaacta
    92041 ctggtgtttc taagcaatat ccttcttttg aaatactttc tatgtcaaaa gttattaatg
    92101 tctgaccttt tttaatctta tccccttgat taacaaaaga tttgaaatat ttaccttcca
    92161 actgaatagt atttaaccct atatgtatca atagttcaca accattatca gatataattc
    92221 ctattgcatg ttttgttgga aataaagtca ttacagtccc atcaaatggt gccactactt
    92281 ttccttcttt aggtgttatt gctacacctt ttcccaatat acctgttgaa aacgctgcat
    92341 cttgtatctg ctccaaagcc tttacttcac cttttattgg gctatatact acttctcttt
    92401 tgtttttttc tataacgcct tgcccattat catctttaga aatttctact atagcatcat
    92461 ctttccaaaa aaataatgtt aaaacaaatc ctactacaat agctactatt attgctatta
    92521 tagttgcata aacacctttc atatctccag ttgttggatt tatataatta ggtataccaa
    92581 atattccaag tccacccatt acataacttt ttacattcat tatccccatt acagctcctg
    92641 ccacaccacc acctacacag ctatatatga atggtgtttt tcttggtaaa gttattccat
    92701 atattgcagg ctctgttaca ccacatatcc ctgaaataac tgcaggtata cacagctctt
    92761 ttatcttctt atcttttaat ttaaagtaca ttgctgctac tactgctgtt tgtgcaaaag
    92821 atggtacaaa tgctcccact aatatggtgt caaaccccat agtcataagg tttgacatag
    92881 ctattggtac taatccccaa tgtagaccaa atattacaag cacttgccac aataaaccag
    92941 ttaatgcacc acataaaatt ggtgaaaagt taaataaagc taaaaatcca tttccaacta
    93001 tattagaagc ataggtagct ataggcccta taaccataaa tcccaatggt aaagaaacta
    93061 ataaaactgc cattggtaca aagaaattct ttactacatc tggtattatt ttagcaaaca
    93121 ctttctccaa cttagctgct aataatacta ttaaaattac tggtactact gttgaagtgt
    93181 agttcattgc tattactggt aatcctaaga aagttatata tactggtgat tcaaatattg
    93241 ttccagtaaa tagattgtat aaaggttgac ctgtagatgc tagagtatct aattgaatac
    93301 ctgaatagca taaaactgca cctataagca ttccaataaa tggttttaat ttgaatttct
    93361 tagcagctgt atatccaaga attattggca tatactggaa cattgcatct ccaattgcat
    93421 ttaacataat atatgcacca tcagtttctc catacaaacc caatgctgta aatactgcat
    93481 taaatccttt tatcatacca gcagcacaca gaactcctaa tattggttga aaaactcctg
    93541 atattatgtc tataaactta ttaagtaatc cttttggcgc atctgagtct gaattatcta
    93601 ttgtatctcc tcctaatcca gccaaatcgc acacaacttc ataaacatct ggaacatgat
    93661 taccaataac tacttggtat tgacctgcac ttttcattac agtaactata ccatccattt
    93721 tttttagcac atcatcattt gctattgact catcttttaa tttaaaacgt agcctcgtta
    93781 tacagtgaga taaactgcta atattatcct ttcctcctac attcgcaatg atttcttttg
    93841 atagttgttc atactttctc attttttctc ctccattttc tttttgaaat atgaaggttt
    93901 ggccaactta atgtcaccac ccaatatata taaacctaat tattaggatt tatatctgac
    93961 ttaatacttt tacttaccac tctttcaacg tgaatagtta agtataattt ttcctcatct
    94021 gttaaatcgt agttgtattt tttatgtata aattcatcca acttttctat gaatttataa
    94081 gcatttttat atttaacttt tattacattt aataaatcat cttcattatt ttcatgtaaa
    94141 ttattactaa caattcgttc tgcaaaatac tttaagtgag taataaatct atgataataa
    94201 actgaatctt catcaaatac tattctgtaa tggtatttaa ccatatttga aatttcttgt
    94261 attatttgtg taatctcata tatagttttt atactttgat ccatttgtgc attaactata
    94321 tgcagtgcta taaatccagc ttcatcttct gatagtctaa tttcaaattt tttttctata
    94381 taatccaatg cctctaaccc tattttaaat tcactcttat aaaatctttt tatatcccaa
    94441 agtaatacat tttttacact tactccttca cgagctcttt ctattgcagt atacatatgg
    94501 tctgttaaag aaatataaat actatcattt aatcttttcc ctagtttttc tttagcatat
    94561 aaaattattt catctgataa ttccatatat cttataggaa tatctgctat tagttcttta
    94621 aatttatcag atatatttgg gtctgaaagt ttgaatatct tatcaatttt atcctttgat
    94681 atatgctctc ctgtacgttt tttataagct aaacctctcc ccataactac tatttcctta
    94741 tgattttcat cagttgtaat aattacatta ttattgagta ttttttcaat aatcattgtg
    94801 atgccccctt tattagcatt aagttaaaaa ataaatcttt tttaattatt tagaatattt
    94861 aaaatgtaat ttattacata aaaaaaaacc tatttattac acattaaata gactcccatg
    94921 agtcctgagt aataaatagg tttagcttgt atttaaacaa tcactatccg tttgtatttt
    94981 attttaatta ttatttatta tatgttagca aatttatttt ttagtgtcaa ctttttctca
    95041 atattttaat tttaaataaa tttatataaa ttgaatcttc aaagtactat ttttatcaat
    95101 aaacaaaata aaaaaggtat tactttcttt aagtaatacc catttatttt taatttaagt
    95161 ggtttttctt aatctcatca agtagtccat cttctaaata aatttctaat gcacatccta
    95221 ccattgcctt tactgctttg tgaagtttat cataagcttc accagaattt gcataattta
    95281 gaaattcttt ttcatgaaca tataccattg gacttatatc taaggctatt tctgtataca
    95341 tagtagggca aacttgactt acattaccta tatctgtaga acctactgga ccatctttac
    95401 cttctaatat atctgttata cctgcctcaa tcaaattatt ctttgttatc ttttgaagta
    95461 ctttgttatt tattatgttg tcaaaagaat tttcaaagta tctataagaa aacttagctc
    95521 ctgtcattaa ctctgcacct tttgcacagt ttataacttt tttagttact tcatctaaat
    95581 aacttctttc agcagctctt acgaaaaact tacaggctgc tttttctgga actatatttg
    95641 gagcctctcc tccatttgaa actataccat gtattctaac atctgatttt acatgttgtc
    95701 ttagtgcatt tatcccagca aaagtaagtt gtactgcatc tagtgcatta actcccatat
    95761 gagggtgact agctgcatgt gctgataccc cttcaaaact aaactctaat gaatctatcg
    95821 ccaaagcctt acagtttata ttattaaaag cttctatatg catttgataa cttacatcaa
    95881 catcatcaaa agctcctgcc ttaactaaat cacattttcc tcctgttgtt tcttcagctg
    95941 gtgttcctat tagtacaatt tttcctttaa aattttcttt taacttactt aatactatac
    96001 aagctcctag tgtagatgct gcaatccagt tatgtccaca agcatgagct ggttctttat
    96061 tttctccata tccaggaagt gcatcatact cagctaaaaa tgctatggta ggtccatcat
    96121 tatctcctaa ttcagctcta aaagcagtct ccatattaca atatggataa actgtatcaa
    96181 atccatattc cttcattttt tctactaagt attttgatga tatgtattct tcttccccta
    96241 attcaggatt gtcaaatata aaattacaaa cttcttcaat ttcttttcca agttcattct
    96301 ctatctcata agctctcttc tttatactct ctatcataat ttacctccta ctagaatcct
    96361 agatataatc ctattgtcaa aaatgccatt acaagaattg ttaatactac cattaaagga
    96421 attacgaatc taacccactt tgaccaagga atattggcta ctgctagtgc tcccattaaa
    96481 acacctgatg taggtgttat caagttagtt acacctatac caaattgata agctgtaact
    96541 atcatttgtc ttgatacatc tactaagtcg ccaagtggtg caagtacagg tattgtaagt
    96601 gatgcaagcc ctgatgctga tggtattaaa aatgctatta atccttctat taagaaagtt
    96661 aaatttataa atatagtttt tggtaatcca tttaataaat ttgctgcaga atttaaaatt
    96721 gtatctatta taaatccatt ttctgctatt attacgattc cacgtgcaaa tgctatacac
    96781 aatcctgctg taattaaatc tcctgctcca cttataaatg aattaactat ctcatcttgt
    96841 ttaagccctg atgctattcc tgatattata cctatagctg taaatatcat tgcaatttca
    96901 gttatgtacc attctagtct taaaactcca tatatcataa tcgccatacc tattgtgaaa
    96961 atggctatta ccatggcttc tctttttgta aattccttta tatttgtatc actattaacc
    97021 attaattctt gatttagtga tatatcgtgt actaaagatt ttttagggtc ttttttaact
    97081 ttattggcat acatcataac aaatcctata gatatagcca tatatattat aaacataaca
    97141 actctaaact ctattccaga acctggtact atttgtgata atgcttgtgc tattcctaca
    97201 gagaaaggat tcgtagtagc tgctccaaat ccagctgttg ctcctataaa tactgtggcc
    97261 actgctgtca atgaatcata tcccatactg gtcataagtg gaataaatat catataaaaa
    97321 ggtagtgtct cttcactcat tccaaacgtc gtcccaccta gtccaaatag aatcattgaa
    97381 attggtatta ttaaaaattg aaacttcttc attttattta cagtatgagc tataacagct
    97441 tctatagctc ctgttttatt aactatccca aaagctcctc caactattaa aacaaatcca
    97501 actacttcag ctgcatctat aaatccgttt ataggtgctg taaatacatc agtaattcct
    97561 tgtggatttg atggtgcttt ttcataagtt ccagctacaa caactgacct tccgtctata
    97621 tctactcttt caaaatttcc acttggcact atccaagtaa gaattgccat taacactatt
    97681 agcaaaaata ttattgtaag tgtctgtggc atagtaaact ttttcttttt taaactgctc
    97741 atttttaatc tccccacttt ttaaattaaa tattttatta ttgcatccct ttatcctatt
    97801 ttgtatagat gtaaaaaagc tcaacatgga tacatgttga gctaaatgtg ctaaatacaa
    97861 catacctgca tcttcccttt atcttgttta agatagctct ccatcaaaat tcgggataat
    97921 tttgatgaca gtactgtacc tattaaatac agtcccagca ctagcttcgg acactagcac
    97981 ttcggcactt actcctttta tattgcctca ttggtttcca acctcttcaa tattaatctt
    98041 agtaaatgca acctctacct caatctgttt gttagatgag gtaattctta ttaattttta
    98101 ttaattcaaa gtaattgtag cataatatgt cgagattgta aatattttca gtataataat
    98161 tcttacttta tgatttcatt ccatttttca caaataattt tttctccata taatttaaat
    98221 actgtagtat attttaaata cacacaaact ttccacaaat tttaaattat tataatacct
    98281 ttataataaa aaataaaagc tatgtaaact tatcaattta cacagcttta tatacattaa
    98341 tctactccaa gtacagcttt aagctttgat gctattgtaa taactcgtgg accaaatata
    98401 acttgaactg agtttttctt tttaacaact ccacttgcac ccaattcatt tacccagaag
    98461 ccatcttcat agaatccatc aattgaattt agctctaccc taagtctagt tgcacagttt
    98521 gtaacatttt ttatattatt acttcctcct aaaccttcta ttatagaatg tacaagcttt
    98581 gtatctttat catctacttc ctcttctact gcattgttgt atgctgtttt accagcatct
    98641 acagattgtc tttctctata ttctttctta ctataaagct taacttcttc tgagcttctt
    98701 cctggtgttt ttatatcaaa cttcttgatt gcccatgtaa atattatata agtaactata
    98761 aaaaatattg gtatcaaaaa taataatggt aacgcatcca ctttttgtgg ttgtaataaa
    98821 ttaggaaaca tatttctaaa tgattctccc attatagaaa cattaaacat ttctgtaaat
    98881 acatacgtca atcctgccag tggtacatat gctacaaaat ataataatgg tgcaacaaat
    98941 aggaatgtat actctattgg ttccgttacc cctaccaaca tggctgttac tattgctggt
    99001 atcaatatac ttattgcttt tttcttatta gcattatcag ccaacttata catagctaaa
    99061 gctgctgctg gtaatattgc aaaatgtatt aataaacgac ctgttgtgaa gttacgagtt
    99121 atataagata gtgtatctgg gtctcccatt tgagctaatc ttatattatt aacaccctcg
    99181 taaattgctc cacctacttc cattgttcca cctactcttg tatattctat agggaatgca
    99241 attaagtgat gtataccaaa tggtaataat gctttatcca ttgctccaaa agtaaatgtt
    99301 cctaataatc cactagaacc tatccaatta ccaagtttag ataatgccaa ccctactggt
    99361 ggccatataa agtacattgc tgtacctaat actattgatg ctataaacat cataatcatt
    99421 gaaaatcttg gacctgagaa aaaagataat gcactaggaa gttctatgtc aacaaatttg
    99481 ttatgtactg cactagctac aaatccagct attatagctc caaatatact acaatcatat
    99541 gaaaagattc ctaagaaaga accatataaa gaacttcgac tatatgcttc tgcctctcct
    99601 aatccagatg ccataaacgc ttctgctgta actgtatctg aatttatacc atttgctgct
    99661 aacaatgtac ttataactgt gtgcattcct ataaataaaa caattcctcc taatgcaccc
    99721 catccttttt cctttttaga taatccaaag gctatacctg taacaaagaa tattggtaag
    99781 tatctcatta ccataaatcc taaatcgttt attactttaa agaatacatt tataaatgac
    99841 ccttctttta ttagtccgct aagccctaat gcagaaacgt tttccatatt tgcaaaagct
    99901 gaccctaacc ctataaatac tcctgctaca acaagtaata taacaggtat catcattgct
    99961 ccagaaagta cttgtaattt atccttcata gtattatttc ctccattttt attgaaatgc
   100021 caggctatat aatgcatata tatatacttc tattgctttg tataatgtat ctatacttat
   100081 attttcattt gcctgatgtg aatttggatt atccccctct attgtgggtc caaatgcaac
   100141 tccatttttt aacactcttg cataagatgc agctcctttt gtaaaaagtt cggcttcttt
   100201 tccaaaacct tgtttatatg cacttgataa tttatttatt aattcactat ctggttttac
   100261 atacagtaat tttaaatcct tatatatatc aattattaaa ttttcttttt ttccaatttc
   100321 attaattcta ttagttataa actcccaact tataccctta ggatatctaa agtctatttt
   100381 catattcaat tcatttttct ctaagaagat actcattata catattgtag aaactcccat
   100441 atctacatct tctttatata tccctaattt ttttccatga ttatcatctg taaagtatga
   100501 atttaaaata tcccttatta taacgccttt atcatttagt tttttaattt tctctaaatc
   100561 ttttgctaaa ctaaatgcac agttatatga cctgtgtgga tttctcgata aagccctttc
   100621 tcctgtatat cttactaata ctttaccttc atctaattct tctatctctg tataataagc
   100681 taatgattct actaaatctt tcttatcatt agttttaaaa acagcctcaa ttttgtcaca
   100741 tacaaatcca tcttctttgt ttgactttat atcaactaaa ttgtgatttc taaatttatc
   100801 tttatctatt ttctttctta gattgaagta taaaatacct ttttctccat ttactattgg
   100861 gaagtttcca tctggagaaa atgcaaattt gggctgttca ttgacactaa agtaatgctc
   100921 catacattcc caagtcgtct cttcagctcc acccactatc aatctaatct ttctcttcgg
   100981 cttttcatta agttctctta agaaaagtaa tgcatataaa atccctatca aaggtccttt
   101041 gttgtcatta actcctctac cataaagata gttatctttt tgacatactt taaaaggttt
   101101 actcttccaa agttctttat tatatattgg caccacatct atatgattaa gcacccctac
   101161 tacttcttct ccttctccat attctatatg aattgcatat ccatcaaagt cttttacaac
   101221 aaaatctttg tcttttgcta tttgaataag cttatcgaag gcatttctta tttctatccc
   101281 aaatggttga tttatatctg ttgtactttc atctctaatt gaaggtattt caactaaact
   101341 tctaatatca tttatgatat tttcttgatt ggattttaaa taatcaataa ttagttcttt
   101401 gtttactatc atcttaatta tttatcaccc ctttatatta attttacaaa gcatttcagt
   101461 tcatatctac attataaatt ttgaatatta ttttttcaat atttcaaata cttctctaag
   101521 ttaccataat gatacggtaa acaatcaaca gattatgaca aaatcatact atacctatta
   101581 ctaatatttt aacttatcta ttacgtcttt tttaatgtaa gtttattcca aaaatacata
   101641 aaaaaagatg tagacttagc tacatcttct tatatctatt caacttccat tattatgcta
   101701 ttaatatcta catttccagg ttctatccta tcttttactg ttctcttaac agaatcagca
   101761 tcatccatta taactacagg agttattata tttaaatcat ttgacgttat aaaatctaaa
   101821 tctacttcca ttattaaatc tttagctttt accttatctc ctgcctttac cttaacatca
   101881 aacggctttc cttctagtga cattgtctct aaacctacat gtattaatat atttgtatta
   101941 tcattactct taatcattat tgcatgcttt gtatcaaata cattgactat ttcaccatca
   102001 acaggagaat ataacttacc ttcacttggt attattgcta ctccatctcc catcatcttt
   102061 tgggcaaaaa ctgcatctgg aacatctttt aagttcacta aatttccctt aaaagggcta
   102121 tatattttct caatcttatt ttcttttttc ttaaatatat taaacataac acactctcca
   102181 cattataaaa ttttatgata atattttttt taaagctttt gctacaccat catttacatt
   102241 agtatcagtt acaaaatctg ccatagattt tacttcatct gtagcatttc ccatagcaat
   102301 accaagacct gcaaatttaa tcatggatat atcattttca ttatcaccta tacaaataac
   102361 ttcttcgcta tctataccta atatatcaca aaatttttta actgcaatac cttttgaagt
   102421 acctttgctc ataacttcaa aatttatctt tccagaactt actacttcta aatcttcttg
   102481 ttttttaaat tcttcctttg cttctctcaa agaatctaca ttttctgaga aaagtataca
   102541 ttttaaaatt tcattatcag ctttttctaa taaagtttca caacttgcat tttctattat
   102601 ttcaattctg tcttcttctt tatttttact atttattaat ctatatggat gttcttcacc
   102661 tatttcattg ttggatataa ctattttaca gcctttaaaa tgtttgttta aattatactt
   102721 ttcacctatt gtatagattt tctttagagc ttctttgctc aaaaccttct tatactcata
   102781 tcccagtaat ttaaaatatg tcccattagt tgatataata tatatatcat cccctaaaac
   102841 acttgtaaaa tatttcatag cattataagg tcttcccgta actaaggcta ccttaatacc
   102901 cttttccatg acttctttta gtgctttaat attttcttct gatacttcaa atcctttacc
   102961 catcaaagta ccatccatat cagtacaaat taatttatat cgcatttgta tcacatccta
   103021 gtaagatttt tctaatattt caacaaggtc ttctttcttt ccaaaaggta aaaatcctaa
   103081 aactggacag cttgttattt gttctaattg ttcctttgtt acattaaact cagacatttt
   103141 tgtcttaagt cccactctct ttaaaaaact ttctatttca tttcctaaag ttttagctgc
   103201 ttcatcatct tccacttttt ctaattcttg gtttagcatt ctcgctactt tggcaaattt
   103261 ctctatatta tccttataga acttttctgc aaattttggg aacactatag ccaaagcctc
   103321 accatgagga atatgtgtaa ctcctcctat tatttcactt agtggatgtg gtgctgctgc
   103381 tccagcattt gccagtgaac ttcctcctaa tgtatctgct actgctaact ttgttctgta
   103441 ttctatatta tttttatctt ccattacttt aggtagatag ttaatgacta attccataga
   103501 tttttcagac attatctctg taaaatcatt agcatttgga tttatataac tttcaaatgc
   103561 atgagtaaaa gcatcaaatg ctgttgatgc agtaattctc tctggcagag ttaacataag
   103621 ctctgggtca actatacatt cttttgagaa acaattttga tgaaatattg tatttttctc
   103681 gcttcctctc gatattactg ctgcttgtgt aacttggctt cctgttccag aagtagttga
   103741 tacagctatt aacggtaatt ctttttcact taccttatcg tatattttaa atggatttgt
   103801 atatgtacta aacatataat cccaatctat tttttctaaa ccaaaagtca atgctaatac
   103861 ttttgcagta tctatacttg aacctcctcc aacagctaaa acaacatcta cagattcttt
   103921 tttagccaat tcaaaccctt catttattaa ttctacagtt gggtttggct ctactctatc
   103981 aaagtgtaca acttctatac ctttttctat taaattcaat gtaactcttt tatataactt
   104041 gtctaatggc tctacatttg gagtagtaac taacaaacat ttctttccat attttcctat
   104101 tattctaggt aattcactta aagttccttg tccaaaattt attcttgatg gttgataaaa
   104161 gttaatcata tttttcctcc cttaaattat tgccttcata ttcaaattat acatatcata
   104221 ggatttttaa ggcaatacct tcactgttaa ctcttattta ctaaagctta tggcaattat
   104281 tagacaataa atgttttatt attaccatat cattatgtaa attttattaa gtacccatgt
   104341 tataatttta taatcaatct tattgtataa ttgacttaat aataaaaata gagtatatac
   104401 acttttttat gacaaatagc ttaaaggaga attaaattat gaaatatttg atagacagcg
   104461 ctaatcttga tgaaattcaa aagtgtttaa agtatggatt taagggaata acagctaatc
   104521 catctatgta tcttaaagag aaagtaaact tccatgaatt tattgagaca tgtgctaatt
   104581 taaatccaga aatattaact gctgaagtca ttggaaataa tttatacgaa ttaattaatt
   104641 catgtgataa gatattaaat ataaataaaa acactataat aaaaataaat ttctctgaag
   104701 ttggcttaga acttataaac atattaaata gtaaaggtgt aaaaactgca tgtaccttga
   104761 ttttcaatgt aaatcaagca tcattagcta taaatgcagg tgctgattac ctattccctt
   104821 ttataggtag aaatgatgaa aatgggaatg atggtataaa aaaccttaca gaaatatgta
   104881 accttatatc aataaatgga tataatacta aagttgttgc agcttctatt aaaaatgtat
   104941 tccacttaac tcaagcatct ctttgtggat gtgattatgc agctgtaaca tatgatttat
   105001 ttaaaaaagc ttcttttaac cagctcacaa tagatggtgc caatactttt gaaagagatt
   105061 ggtccaaggt taataaatag taactaagat ttaggagggt ttgcattgaa caaaagatta
   105121 ttagatattg ctgaattatt actcaacagc tcagactata ttactgtaga tactattgcc
   105181 gaagaattaa aagttagtaa taaaactatt cgtaatgacc ttgttatttt agatgaatgg
   105241 cttttagagt ttaatttatc cctagataaa aaaactggtt caggggttat tattctaggt
   105301 aatgaagata taaaacttaa agttattaga gatatcaatg ataaatcaaa ttgtatatat
   105361 gcatactctc ctgaagatag aaaaaggtat attctaagta aattatttat taaaaattct
   105421 aagtttagga ttcgtgatat ttgcaatgaa ctacatgtta gtagagctac tgtgcataaa
   105481 gacttggtag ttattcaaaa ttttttgcaa aactttaaag tgactctagt tagaaaaacc
   105541 aataatggag tatatttaga gggaaaagag aaagatattc gaaaagcaat ttttgaactt
   105601 gctactgtta ataaaagtta tactgaactt aaagaaatat tattctcgaa atctaatgaa
   105661 tgcaaagata ccccatcaac aaaaatattt aaggaactat ttaactatga ttttgagaaa
   105721 ttatctcaaa tcactctaca caccttacaa gtagaaaaaa gtaaccttag tgatgagtat
   105781 tatataaact tcttaataca tatagctata tgtattaaaa gaatttcaat taaaagatat
   105841 attaacttat ctgaaggttt ttttagagaa ttattagaac atgaatactt tgaaaaatca
   105901 aaaattttat gtgctaacct aagagaagct tttgacgtag agtttattga tgaagaggtc
   105961 tgttatatcc ttcttcatat agaaggatta cttaaatcaa taaagaaaac tactactctt
   106021 gaacctctta aaaatgaaga aattacagag tataatctat ctgaagcaat agctgttcat
   106081 tggggaagta tactaaactt aaacttaaag gatgatttaa tattaataaa gtctcttgct
   106141 aatcacctta aatcagttct acacagaata aactatgggt ttactattac aaatcccata
   106201 ttaaatgata taaagagaac atttccttat acttataagg ctgctaaaga gtctaatact
   106261 gttatcaaac agttgatgaa ttatgaagtc aatgatgacg aaataggata tcttgcttta
   106321 tatttaatat cagcaataga tagaagcaaa tctcccctaa atactatttt aatatgtcac
   106381 tgtagtgatg gtgtatctaa tttattagtc caaaagttaa gttttgaatt taatcagatt
   106441 aatatagtta aatctatacc tctatcttct atttcattta cgaactttga tgatgtggac
   106501 ttaatactaa ccactgctcc tgtagacttt gaacataatg ctgaactgat aaatataaat
   106561 gctcttttaa gtaagaatga tatttctaga cttagtacaa ttataaaaaa actatattct
   106621 gaaaaaaata aaatattatc ttataaataa acaaaaatag gcttgtctca acatagagat
   106681 aaacctattt ttcattgtcc aaatgataaa aatatatttg atttcataga aaaagtgcct
   106741 catgaactaa aaaattcatt ttgagacacc ttcatttttt atatttaatc tttttattta
   106801 agcttttata ttttttaaac ttttatattt aaagtaaatt ttattatttt tattgagcac
   106861 aagcattatt tatattatta atttcttcag tattcttacc aaactttgta gttacaaatc
   106921 ctattgtttt tattatgagt aataaggata tcaatgaata tatagatatc ataaaattct
   106981 tacttattat tccagacgct actattataa atccatctag cataaataat ataactggca
   107041 acttcagaaa cttaattacc ttattaataa gcattgcaac taaatcagtt ccaccagtac
   107101 tacagcccct tattattgct atccctatag cagttcctac caataaccca cctatcactc
   107161 ctgctactaa tagattgtca gttatgtgag tttgtggtat tacttttaag aataatgggc
   107221 ccataagagt tatatataat gtttttattc caaaaccttt ccctaaaaat aataatccca
   107281 ttactaaaag tggcatagat attcctaatg atatattctc aacaggcatt gataagaatg
   107341 tgctaagtac gactgataat cctgttatcc ctcctggagc taatgtatgt tctgcaaaga
   107401 aaaaattaac tgctaatgcc attaaaaatg ctgatattgt tatcagtaaa taatctttta
   107461 tcatttcttt tttcatttaa taacctccta tgattatatt gtttcagtat aaaaaatcaa
   107521 ttaaattagt ctagcttcct gtagtttttc ataaaattaa tgcttcctta aaacattaag
   107581 aaagcatctc ttttatcata gtttattatc ttattctaaa ccaaactttg tagctgcttc
   107641 atctatagct tttctacaat tcttaacacc tgctgttata ccatctttat ccttgaatat
   107701 tgctgaagat aatattacaa cgtctgggtt acattctatt aatggctcca tattgtctgc
   107761 tcttagtcca ccatctattg ctaattcaca cttaggattc ttttcgtcta tcatttttct
   107821 agctcttttt actaaatcaa cagcactctt tctccatccc cagttatctt ttccatcagt
   107881 ttcatcaaca ccatgaacga ctatttgcaa tctatctata tcatatatag cttcatcaac
   107941 aaaacatagt ggtgtgtaac atccaattgt taatcctact ttcataccaa attctctaca
   108001 gtaatttatt atgtatgcaa gaggagcacc taaaaaatgt tctgctggta ttatcaacaa
   108061 gttacatcct gctgctgcta ttttttctat aaataatcta tcacaatctc ttgtgtatat
   108121 atggcattct attggtttat ctgtcaccgg tcttattgct tctattattt gatgaccacc
   108181 cataagttgc atatttttta agtcatgcat atctgctgca tctgaatgta cgtagtctac
   108241 acctgaatcc attgcttctt taactacggc tgatatatga ccgtaattta catgtgctaa
   108301 tcctgctgct atttttatgt gtttcatatt tgtatacctc catattttac tttaattagt
   108361 attaaatatt agtttttgat atttttttaa tattttttta atatttttta atccagtatt
   108421 acttttattt agcattactt ttattgctgt atatatttct tttatgaact tattctgctt
   108481 ttgttaactg tgaacttatt ttgctttgta aattaatatt acactgatat attttttttc
   108541 acaacacttt gactactcct taaaagtacc tttatattgt ggtaaattat agacattaat
   108601 tgtatataaa aagttagttt tttaccacat tcttatggca tttattgtct atactaactc
   108661 aattgatata gctagttcat ttaatatata atcagactat aaatataaat ttactcgata
   108721 aaaagtacca ttcataacaa tattaatgaa agggagatgt aaaatgagaa actgtattat
   108781 tgcccaatct ggaggcccta cagctgttat caatgcttct gcagttggta tttatgaaaa
   108841 aaatttagaa actaaatact ttgataaagt atattttggt atcaatggga ttgaaggtat
   108901 attaaacaaa aatataatag attcagactc cttaaacaaa gataatgtat taaatttaaa
   108961 gcaaacacct tcgtctggtc ttggttcttg tagatacaaa ctggctgatt ataaaataaa
   109021 ttcttatgat tatgatagag ttataaatat actagatgaa tataaaatag atacattatt
   109081 ttatataggc ggaaatgatt ctatggacac agtgatgaaa ttttctcaat actgcaaaaa
   109141 cactacttgt aaaataaaat ttataggtat tcctaaaaca atagataatg atttattagg
   109201 aactgacaac tgtcctggat ttggttctgc tgcaaagctt atttctacac taataatgga
   109261 aacatactta gatttttcta tatacaaaaa taatggtata tttatagtag aaactatggg
   109321 tagagatact ggatggttag cagcttcttc ttcactagct agacttaatg atactccact
   109381 tgttgattta atataccttc cagaaattga tttctatgaa gataagttta tagaagatgt
   109441 tagaaaaata tttaaagaaa aaaataaggc ttatatagtt gcatcagaag gtataaggga
   109501 taaatacggc aactttatat gcgaacaaaa aacttctgct catgataaat ttggtcattc
   109561 ccaattaggt ggagtaagca actatctaaa gaatcttata gtatcatcat caattacaac
   109621 aagagtaaaa accttagaac ttggtgtaat acaaagatgt gctatgcatt tagcttcaga
   109681 tactgattta aaacaagcag ctgaagttgg tgcatatggg atagaactat ctaaaaaagg
   109741 atatacagga gttatggcta tcattaatag aacatgcaat aatccttata agtatgaagt
   109801 tagtcatact gatatttcta aaatagctaa caagacaaaa tattttccta aagagtggat
   109861 aaatgaagaa tgtaattata taactgatga agccctaaat tatctatatc cacttattca
   109921 aggtaaacca gatatcaaat ataaaaatgg actaccttat ttttcaatta tttactagga
   109981 aattattata atttgatata cactcaattc tatcgctctt aaatacctaa gtggctgtta
   110041 aataaaatta taaattgtta tatgacagtc acttaatcgt ttaattattt aactgtttag
   110101 ttttttaatt tttttaatac taatacaatt tgttgtaata atatctcaca cccattttca
   110161 ttttggatag attataatta gttagacaat aaatattttg tcatgatatt attatatata
   110221 gtgatacaaa tagaaatact tttatcatgg ctagaaaaac aaagattaca caaaggattt
   110281 aaaaatcaaa caacttcaat taaaataaat ggttaaaata acttctaaat caactacata
   110341 aacaataaaa gaacataaag tagttaaatc tacaattata aaattagtaa gactataata
   110401 acttaaataa aattaaagtt aacaaagact attaaagtta gcaaatattc ctctacctaa
   110461 ataattgctt tttataaaga gttatttatt ttaattgaat ttaattgaaa tacgatttta
   110521 actagaacaa tagattaatg taatatttaa tataaaataa ctataataat tgaaaaggaa
   110581 gtaatctatg atgaaaatag cagtcataac aaccgaattt ttaaaagagt ttgtagataa
   110641 ttctataaaa aagttaaata ttaatgcaga aattaaaata tatatctata gagatttttc
   110701 tcatgttgga gatttatatt tggaaataga agataggttt gatggatttg cagttagtgg
   110761 ccctatcccc aaaaaagcta ttacaaaaaa ggctggaact attaaaaaac ctctagttga
   110821 ttttggtact gacttacaaa gttactatga tatgtttcta aagcttatct ttaaatataa
   110881 tacattagat ttttccagag catactttga cttaacagac tgggcagata atccaaaaga
   110941 tatatcatac tatttatcaa atggcacatt tggagactta atggatagta ttgatgaaaa
   111001 tgcatctaaa atgagtttat ctgatatagc aaaacttgaa aaaaagattg caaaaaaaca
   111061 tattaatcta tggaatgaag ggaaaatcga tttttctact actcgtttta gtagtattgt
   111121 tcctatgtta caaaatgcag gagtaaactt tcatttcata taccctgata tagatttatt
   111181 aaaaaatact tttaataact taataaaaga tattcattta catagaatga agggaaatca
   111241 accaagtgta atatatataa cagttaaaga tacaaattat gatgactcta ctctagacca
   111301 agtttataaa atattaaata gtattaaaaa agataaatta accgatttta taattgaaaa
   111361 aaatagtaat tcttttaaaa ttttcactaa atgtgaaacg attaaatcat taactaaaaa
   111421 ttttactgca tgttacataa aagaatctat tgaaaatagt acaaatatta aagtatgtgt
   111481 tggatatgga attggtaatg atataaagca agctatgtct agtgccataa gtgctaataa
   111541 ggaatctaaa ataaatcctt taaattacag tttcttagtt aacgaaaatt atgagacaat
   111601 aggaccttta ctgtgtgata agttacttac tgtttcaaat aaagtaactc cacatataaa
   111661 tacaattgcc aaaagttcta aattgtctac tcttactatt caaaagatta tatctgttac
   111721 tgaaattcta caaagagatg aagttactcc taaggaatta tcttcatgtt taaatgtaac
   111781 agttagaact gctaatagat ttctaagtag tctcttaaag tctggaaacg ctactatatt
   111841 atatgaaaaa caaaactcaa caaaaggtag acctgaaagg gtatacaaat tatttatatc
   111901 agaaaataaa tattaaaatc caaaatgcat aaaaatattt tatcatctaa tattaagtaa
   111961 aattatatat gactttctaa aaggtatatc tttgcatctt tttaagatat accttttatg
   112021 atatttaata atattttatg ttattatcta ctaaaattat tttctaacca ttttactgca
   112081 caatgagcaa ataaagctga accataaact aatccctctt cattaaaaat tgctttagga
   112141 ttatgcatac caaaattata tccctgacta acacttccca ttccaatcca taaaaatact
   112201 cctggaaccc ttagtaaaat ctctgaaaaa tcttctgaac ccattgcaga tggaaagtct
   112261 attacatttt catttcctat aacttcttta acataagata caatctcatc tcctacatcc
   112321 aaatcattta taactgcagg agtccccatt ttaaattcca ctttagcatt tcctccaaat
   112381 gatttagcta ttcctgtaga tatttcaata attctatttt ttaatttttc tctaacaaat
   112441 tggtcaaatg ttcttaaagt tcctgacata gatgctttat ttggtatagc atttgctacg
   112501 tttcctgcat taaacatacc aatagttaaa actacaggtt ctttctgagg tttttctctt
   112561 gaaagtatag tgtttaatgc tatttgtata tgcgacatta tgtttattgg gtccactcca
   112621 aattcagggc ttgctccatg agttgctttt ccttctactg ttatttcaaa tatatccgca
   112681 gatgccatag ctggaccacg tgaataagct acttgacctg tgttaagaaa tttacccacc
   112741 atactgtgaa atgccatagc tgcatcgacc tgaggatttt ctaatatacc atcatcaatc
   112801 attgattttg cacctctgct agtctcttca tctggttcaa atacaaactt tactctacct
   112861 ttaagtaagt gcttattatc cataagtatt ttagctgctc ctaagagcat tgctgtgtga
   112921 ttatcgtgtc cacaactatg agatgcatct ttattcttac ttttaaaagg taaatccgtc
   112981 tcctccataa taggaagtgc atccatatct gcccttaata ataaggtctt tccaccattt
   113041 tcactgtcta aaacagctac tattccatta ttagatgtca atttcggaga atatcccatt
   113101 ttttctaaag tactggtaac aaaggttact gttttcggta gattgcaacc aatttcggga
   113161 ttttcatgta aatatcttct ccatctaata atttcccctt ctattgactg cgcttcttta
   113221 aaaaaatttt tcatattcct tcctcctaat cagatagtca gcaaaatctc actttctttt
   113281 agtaatgaaa tgatgctgat ataaaaatta taattttata tattaaattt catgtctttt
   113341 taaggagttg gaatatcatc tggaatagga catttatatg ttttaccatt catagattta
   113401 tcaaattctt cttttgcctt tttagctatc tctggattat ttaatatttt agctccaaac
   113461 atagccataa tttttgatgc atatatcata cctttttctc ctatagaact tcctgcacaa
   113521 gatgtaaact gccagctatg acctggtgct cctagattcg tacaccctgt aaaaaagtat
   113581 gctgtcggaa ctatatgcat tacatctcca atatcagtag agccataact attaaagttt
   113641 gtaacatttc ctccaccata atatagatga gttccttctg gcaaattata tttacttatc
   113701 atagccttat attgttgtgg gctttgtcta tctaattcag ctgcaaaatc caattcctct
   113761 agagtccaag gctcttgttt aatctcattc atacattctg atacaagatt tgctaaaaca
   113821 tgattgttta aagtattata acatcctcct aaaaactcta cttcaacttc agtttcagtc
   113881 atcattgcag ctccttttgc tacctttaca agtctttcat atgtactttc tacagcttct
   113941 ctacttaaag ctcttgtata ataccatact gatgctttat caggaactat gttgggtgct
   114001 actcctccat ctgtaattgt ataatgaatc cttacatcag aagtaacatg ttctctcaaa
   114061 taattagctc ccacattagt aagttccaca gcatctagtg cacttcttcc attttgaggg
   114121 tctgagcctg catgtgcagt ctttccctta aagtgaaact ttacagaatt aacagctgtt
   114181 gaagtaccaa ttgtagcttc actaatttta tttggatgaa aatttatagc taagtctaac
   114241 ccttcaaacg ctccacctct agccataaat cctttacctg ttaattgttc ttctcctgga
   114301 catgcataaa atactatagt cccacttaag ttattttcta tcatctctct tttaagccct
   114361 actactgccc ctacatgtgc tgtacataat aaattatgcc cacatccatg accatatgca
   114421 cccaattcaa atgcttcttg ctttgttgaa actttttgat ttaaaccagg taatgcatca
   114481 aattctccca taaaacctat aactggttta cctgaaccaa aactagctct aatagccgtg
   114541 gctaaacctc ctacacctac ttccacatca aatccttcac ttcttagaaa gtttgctgta
   114601 ttttcacatg ctttaaattc tttaaatgct ttttctggat tttcccatat tttcttactt
   114661 aaatcatcaa gtttgaatct ttttttatct atctcattta tagatatact tcctatcatt
   114721 tcttattcct cctataagta tatttactat caaccaaata taattggacc tattatacta
   114781 gcaaatgcca ctgatgcaat ggttacagta acaaatcctc ctataatcat ctttggtaat
   114841 aaataatctg ttgccctttg tttttcttct tcagttcctt ccatagcatc aataccttcg
   114901 ttggaaatta tctgtgttgc aggataagct agcatacaag ttacaccaat tgcagctgac
   114961 attcttggag aatatcccaa tagttttcct acaattgcag taaataatat tataaataca
   115021 gaacctacaa caagtattcc tatagttgga acaatcatcc caaacaatgc tgttggagtt
   115081 accttagcaa gtcctccagg taacatcaac atacaaccaa acattataat tccattagat
   115141 tgagatttat ctaaaattcc tttttctaaa aaacctattc gtgtaaaaat caaccctact
   115201 aacaaacatg ctatattagg atttaaataa tagtttgcag gggtaaatcc tggtattaaa
   115261 gtagccaatc ctacaaaatt accaatcata gcaacaaatg aaagctttgc aagatacact
   115321 agagtagatg attttttacc taaatcttct ttaaaaattc tcatacttgg aagtttaaaa
   115381 ttactttttg actcatcttt caaaaaatcc ccgttatctc ttttaaattt taattcttta
   115441 tttatacaat atgtagttat cggaatacca aagaactttt gaaatgataa tactagaatt
   115501 acaaatgcag caagttcagg tctatttgca gcttctgcaa cagttgttac gataatccca
   115561 gcaacagtag aacctgctat tggaggtgct gctattaaag catactctct gccaaataac
   115621 atactaccca ctgttaaaca gccaactcct attcctacaa tacctactaa tgcaattaca
   115681 accgttttcc attcatgaca taagtcttca agatttataa gtgttcctaa gttagttatt
   115741 aataaagcta taccaaagtt gctcattgca gctaatatcc ctgatgctcc tgtaatgtct
   115801 tttggtaaaa tatttgtcca aaatcctagt aaaaatataa tacatacaaa taacaatgtt
   115861 gaaattgcac cttttgtttt cttagataaa aactcactaa aagcataaat cattacacat
   115921 acagtaaagc aagtaagtgg attccaaaaa ttttccattg ttgtttcctc ctaaatataa
   115981 taatttttta tcaataaaac aataattata aaatgtatat tatgcagtta ttcttaacta
   116041 catatggtat agcttgatat tttttgatga tattatatac gtcctaaatt attcctaaaa
   116101 tatctaaata aatataacta gagttaactc tctaaatatt aactatagtt atcaacttgc
   116161 tagatttctt tttgattttt actttctaca taattttaca agttagaata gtacttcaac
   116221 tactctctat attaatatac atgttggaag acttatattt atttaaatat tagatataga
   116281 atacattttt ataaacgtct taaattattc ttaaaatatc taaaacgaaa taataatata
   116341 cccattaaac caatattatc agaatatact tcactttaag tcttctttat atagaaattt
   116401 tatctattag tgcatcccct cctttgtaaa ttagactatt tctaaacgaa tttagatatc
   116461 ttattcctag gaactattac tagaaacaga aattatttat tatattaaat caatgataag
   116521 ccatacttta aaattctttc tatacaagta tgatttatca tataatgaca tctatacctt
   116581 tatctttata gtagtcctaa attattctta aattgacaat aaaaataatt tcactatttg
   116641 taaaaatact tgtttttata ttgtcaaact attcttaata tagattataa ttttaaatct
   116701 tttctttgtc aatatattct gacatttttc cagaaaattt ataaagttgt atagtgagta
   116761 aatcatacta tttttatata atgagtaaat tatactatga atatgtctaa atatttactt
   116821 aagtataaac ataaaaaatg tgtattctcc tttttatagt aattttagtt gccattactt
   116881 ttaagaagaa tacacacttt actttaaaga ccctatactc tgttttaaat gctttactag
   116941 acactaatta acattagttc ctaacttcta tttatcttat tcctacccta ctactatatc
   117001 cgtagaaaaa tctaaaactt ctccattaga ttttattact tctttgtacc aatcaaatga
   117061 ttttttctta tatctcttaa aacttccttt gccttcatca tctaagtcaa catagataaa
   117121 tccatatctc ttactcatct gacctgtagt tgcactgact aaatcaattg gtccccacat
   117181 caaatatcca aaacattcaa cattatcctc ttcaattgca gacttcattt gagatagatg
   117241 cttacttaaa tattcaattc tataatcatc atttatagtt ccatcttctt cgattttatc
   117301 atatgcccct aaaccatttt ctgtaattaa gataggtaat tgatactttc tgtaaatata
   117361 gttcaaggta aatcttaaac ctatagggtc tattgcccac ccccacttac tttgttccaa
   117421 atatggattt tgaatcccac caaataaaga tttatcacct gataaatttt cttttggagt
   117481 agatacactt gaaaaataat aattaagtcc tataaaatct aacttacctt ctttaaatgc
   117541 ttttttgtct tcatcagtca cttcaatagt tatattattt ttttcatatt cttttaattt
   117601 atattgtgga aacttcccat tgcacattgc atcaatttga taataatcac ggtcattatc
   117661 taaaaatgca tttaacacat tactaggatt acaattgtat ggataaattg gatttagtcc
   117721 aaatacacat ccaactttat tgttgggatt gatttctcta gctaactttg caacctttac
   117781 acccgccaaa gtcatattat accctacatt tgccaatgtt tgaaccttat tttctatttc
   117841 actatactta atacctgcta tcatataagt aaaaatatcc gagtgctctg tttgagggtc
   117901 aatatggttc atctcattaa atgtaaccca gtactttacc ttatcatcaa atcttcttat
   117961 tacagtctca ctgtacttta aatacaaatc tataagtttt ctgttattcc atgaaccata
   118021 tttatgtact aaattcatag gtaattcaaa atgatatagt gttacaatag gttctatatt
   118081 attttctatt aatgtatcta tcagaccttc atagtattta atccctaatt cattaggatt
   118141 ttcatcatct ccattttgaa aaattcttga ccaatctata gatattctta atgcactaaa
   118201 tcccatttct ttaaataaag ctatatcttc tttatatcta ttataaaaat ctattccatt
   118261 atgagatgga taatccaatt tttcttctat tttatcagta attactcttg gcgtttcata
   118321 agagccctta gttacaaaat ccataattgc aggtcctttt ttatcactat cccatgaacc
   118381 ttcacattga tgggctgcaa tacttcctcc ccagaaaaat gtatctttaa tattcatgaa
   118441 ttttccctcc taaaatttat actattacag ttaataattc ttctgattca tcatttgatg
   118501 agattacatc taaataatcg ctagtatttg taactacagt tattatagta gaatcaaagc
   118561 cttcctctat aattttatca gattcaaata ctgctaaagc atctcctttt ttaacccttt
   118621 gattttgtgt tacaagactt tcaaagaatt ttccatctaa gtttacagta tctatcccaa
   118681 tatgaattaa tatttctaat ccttcatcag tcactatacc atatgcatgt ttagttggaa
   118741 atactatagt tatagttcca tctacaggag atataacagt tgattttgat tcactaggta
   118801 taactccaac ccctttacct aatgctccag aggaaaatgc tttgtcatta acttccccaa
   118861 gtgcaattac ctgacctttt gcaacatttc caatactaat agttcttgaa ttgttctcgt
   118921 tgattattag ttctaattct ttttcattat caccattaac ttcttctttt tcatctgaag
   118981 gtattcctag taaataggaa gctgctgttg ctgctacaaa tgatactact acacttatta
   119041 tcataaatgt aaagttagat acctctcctc caacaagata tgttggtaat gcagctaatc
   119101 cccaaaccat tccatatgtt ttaacttgag ctaaacctgc tattaaacca cctatacccc
   119161 cacctatcat tactgctaca aatggtcttc tatatttcat aaacacacca aacactgaag
   119221 gctctgtaac tcccataagt gcactaaaac ttactgtacc aaataattgt ttttgttctt
   119281 tattcctagt ttttaagaaa tatccaaaca ttgcaccaca aactgcaata tcagatattg
   119341 ttgcagcacc cataaaaatt gggtcatacc ccaatgttgt cacagaattt aaagctatag
   119401 gcatagtaaa gtttgctgca ccaaaaacta ttaagagtgg ttgtaaagct gcatacagtg
   119461 caacaacact ccaattaccc aatgtatcaa ttaaaaacat acatgcatag tttaatccat
   119521 caccaatcca cataccaata ggtccaaata tagttaatgt aactgataga gttattatta
   119581 aagataatac tggaactaaa aaatagtgta gtgctttagg taatattttt ttcaaacctt
   119641 caattataat tcccattgcc catactccta aaagtattgg aataaaactg tttgcataag
   119701 ttgtagcctg taaatttata ccaaataaac ttaatccttc tacaccatct attgatgaag
   119761 ataataacgt aactgctaac actactgcta tatagggatt tacattaagt ctttttgctg
   119821 atgctattgc aattaatact ggtaagaagt gaaatgtagc acttcttaat gtatctaata
   119881 tttgatatgt aggactgtca ctctgaagta tgccagacat atttaaaagt gctaatatac
   119941 ttgcaagtat accagctgca agtagtactt caattactga agtcatagtc tctgagacta
   120001 ccacaaagat ggaattaaat atacctttga tacctctaat tccctttttt ctttcacttt
   120061 ttatacttga ttcacttgaa cttaaaccta tcatagacat aaactcgtta tatacatcta
   120121 caacatgagt acctattata atttgataag caacatcatt agaaactaca tcaattactc
   120181 cttttaattt tttaatttct tctgtttgag cgatactcct atcatttaaa gtaaatctta
   120241 aacgagtaac acaatgcgct accgacttta tattttcttt tccccctata agttttatta
   120301 tattttcatt taaatcttta tatttcatct gattttgcct ccagtctttg agtcacccta
   120361 tttatatgca acattaaata agtttcttca cttatagata tatcgacatt aaattgtgat
   120421 tttatatatt ttcttatctt ttgaacactt ccaaatgact ttggataaag ttgacttact
   120481 tgtttatata aatctataga attatcttca tctattgaag cttcatccga cataattctt
   120541 tggataaagt actgtagatg agtagtaaat ctcatataat ttgttgaagt ttcatctagc
   120601 tctacattaa aatgatattt tattatagaa actatatctg ctaaagttct caactctaca
   120661 attgtactat catgagactc tttatttacc tccatattta caaaatgaag tgctattgat
   120721 actgcctcat catcaggaag attaattccc ttactatcac caattaattt tagtgcatgc
   120781 attccaattt caaaatgctt tggataaaat cttttaacat tccataccaa aggacttttt
   120841 ataaattgat tcttttcaca tcttttaagt aaaaactcta aatggtctag taaggttaag
   120901 cttagataat cacttgactt tatatttaaa gctttctcac catattcaat tatttcatta
   120961 ataagaacta tattattgga gtctgagttt tgtagtagat aactaaagtg ttctagcata
   121021 tcgtatgaat ctagtatata tgttctctct atttcatttt catttattac ttgtcccact
   121081 ctttttttaa agccaattcc tttaacaaat acaataattt catttttacc tctttttact
   121141 aaggctacat tattatttaa aatctgaatt attttcatat attcctccct tcaataaaaa
   121201 gaactcaagc atatatgtat agagtatccc tctatttttc acatatatac ttgagttctg
   121261 cctgctaatc agtaacatac tcaaaattat gactacgtcg ccataattaa aattcttttt
   121321 tgtttaattt catattctat atgttatact atccatataa atctgtcaac ggtttcctag
   121381 atattttttt attctataac tacaagctct gttatgcgat tatctgacaa ggtttatata
   121441 ctaaattgat actattttac cgtcactagt atttataata ttgtctgaac cattatctat
   121501 tttactatta tgaattatca tagtaatgct tttaaatata atgaactgta tgttaacaaa
   121561 taaattctta agatatatta acatataaag tcttaagttt agttttattt aatcactatt
   121621 aagatatatt aataggtaaa gcttcaaatt tagtttcatt taaatgctag taagatatac
   121681 taatatataa atacttaaat ttagttttat ttaaacactc tagtgatatt tttaaataaa
   121741 ttttaataaa aatcattcta ttttgtcata aatcatttat ctggcttata tttaagatat
   121801 attggtggat actttacact ttttaattcc tcattacttc ttaaaagttt attattattt
   121861 tccatatcat aaatttgtaa cattacttta tttacatata gagcataata attatcacta
   121921 taaaaatatt gatactcata tcgagggtca tctttgtaat acactttgta tagtattcct
   121981 tcgtaacttg ccttcttggc tttttctttt gtaatacttt ttatattatc ttttgaaata
   122041 tcttgtttta ccatatactt atcaatatat gtttcagcat ctttccatgg tttaatgcag
   122101 tttttatata caacaaaccc tgttacactt ataataccta taattaatac tataaaaata
   122161 actttatatt ttttcatatt aatcctcctt catttattat ttaaaactcg atataatgca
   122221 ctaaaaaaag gatgttatct tttttattaa aatataacat ccctcatatt tagcatcaat
   122281 atatatgccc caactggtag gttaaaagac cccactgtca gtactttgat taaattacat
   122341 gtatgtatat atatttttaa caaatctatt atatgtcaac ttgtctacta ttacatataa
   122401 tctgtaatat tacatctgct gctttttttg agcctcctgc attataaaag ctttttgata
   122461 gtttagttgc attttcttta tattcattgt catttataac ttgaaatact gcttttttaa
   122521 tactttctga cttatcctct tttaacataa ttcctgctcc caaatgaaca actctcttag
   122581 ctaccattct ctgctccgaa tgttgaggaa ataataccat aggtactcca taatataaac
   122641 tttcattaac actattcatc ccagaatgag taacaaacac atcagttttt tgaagtatag
   122701 caatctgttc aacactattt ttgacctcaa aattatttgg tatatttcct aaacttttaa
   122761 tatcagtact tctaccaaca gacataatca catcaacatc agaatcttta aatgcactta
   122821 tacagttttt ataaaagcta acatttttat tattaattgt accaagcgaa atatatatta
   122881 gctttctttt tctctcttta ggttcaataa tcaactttga tactgatgga cctacaaatg
   122941 aatacttact agagaaggtt tctaccattg gttgaaattc ttttgatgta tatacaatgg
   123001 tatccgtatc attatcatta gaaactatag aaataaaatt ttttacttca tacccttttc
   123061 tttgtaaaag ctttattttt ttattaatgc gtcttacacc aaaaatcata cgtataattt
   123121 ctataaagtt ttgtttcatc aactttgctg tatgtttatt aaatgcaaaa gttgttgtag
   123181 agcatacata tggaatatta agtttttgtg caaataactt tccccaaaaa cttaatgaat
   123241 ctgatacaat gcaatctgga ttaaaatctt taagttctct acaaactttt tcatctaaag
   123301 aaatagtagt atctactatc atctcaatta atccaggaaa atccttacca atttttttct
   123361 catctccagg gagtaattct ggaaggtatt tatcacaaca aataaatttt gctccagcac
   123421 cttcaatttt atctttaaat tcattaaaag aataatacaa tacctcattt cctctatcca
   123481 ctaattcacg aactacttca atagtaggat tagtatgacc atatgcagga atgctaaaaa
   123541 atactatttt actcatattt catacctcct tttataattt ttttaaatca ttcttcttta
   123601 cgtactactc ccacatgacc tataaaattt atcaaatcac gttgatgaac aattcctaat
   123661 cctctttcct catctccaag taccaataat ttatctcctg catttatatt aaatacttct
   123721 cttgcttctt ttggaatgac aatctgacca cgttcaccaa ctacaactgc tccaaagaaa
   123781 aactttcctt taggaggtac tataatacct gttttttctt ctgaatgatt aactaagtca
   123841 tctagtttga cattgtacaa ttttgcaagt ttaatgcaac tacatatatc aggaatagat
   123901 tctccacttt cccattttgc tattgattgt ctagaaacat taagtttttc agctaattct
   123961 tcttgtgtat actggttgat ttttcttaga ctttttaaat tctcattaat catatttttc
   124021 atacctccta tgtttataat attggattta ttatttaaat tctatcaact aatcttaaca
   124081 ttcatatata tatttatata cttttattat ataaatttat tattcaggta acatatttcc
   124141 ttaagttatc gtaaacaaaa aaacaagcac aaatctacta actgttgtta aagtatttaa
   124201 gttaaggtca tttacattat caaatatttc tacaccttta aaataacctt tatatttata
   124261 atctttcata agcaaattat tatcccttct catatacaag tccagttgat gtcttgttgc
   124321 taaatttaat ggtaatcaaa ttctttacca ataagtataa aaattactaa tgtgttataa
   124381 ttttcttaac tactaaattt tacatacatt tgaatagaat atatcaataa attactataa
   124441 taaataaaaa atagttaggg agatattatt atgattttat attttagcgg aactggtaat
   124501 agccgatatg tggctcgtaa aattgcacaa gaattaaatg atgaactgat atcactaaat
   124561 caacttataa aagaggaaaa aacagatgaa ttaatatcag cagataaacc attcatattt
   124621 gtatgtccta cttatgcatg gagattgcca atagtagtta cggattttat aaaagaaaca
   124681 aaatttctag gaagcaacag agtttacttt gtaatgactt gtggtggaga tacagcaaaa
   124741 tccataaact atattcaaaa actatgtaaa tacaaggaat ggcaattaaa aggtatggca
   124801 gaaattaaaa tgccagagaa ttatatagct ttattttcta caacagacaa agaaacatca
   124861 aaacaaatga ttaaagaagc agataaacaa atatatagga ttatttctga tatacgcaat
   124921 gaaaatgaat ttgaaactat tactcctagt ggcttaggag gtacaattaa aagtggtata
   124981 ataaatacag ttttttataa gacaattatt agtgccaaag gatttcatta tactgataaa
   125041 tgcattggct gtggaaaatg tgtagagcta tgtcctttaa ataatattaa tttaaaaaac
   125101 aaaaaaccag tttggaaaaa taactgtact cattgtatgg catgtatttg tggttgcccc
   125161 actgaagcta ttgagtataa aaataaaact caaaacagag aaagatacta tttagaataa
   125221 tatattctta atatttaaac cattataaaa tgaactatac ccattgtttt atacagtttt
   125281 acatatttta accgtctcct aaaatgggta tagttcaaaa gatagtgtct caaagtgaat
   125341 tttttagttc ctaaatcaat ctttttgtat taaatcaagt ataatttaat caccttttct
   125401 tatatcattt tcactaatat gttgtattcc aacaaatata agatttatta gctctgttag
   125461 tgacttccat tgtgattttt ttgaatcaag ataataataa tttttcgttc cttctctacg
   125521 caaattaaca atctctgctt cttttaatat cttaagatga tgagatacag caggacgaga
   125581 aagatgtgtt ttttttgtga tttctcccac tcgtatacca ttaaaatcac tctctaaaag
   125641 agcaattaaa atcaattgtc tagtctcatc acccatagca gagatagctt tgcgacattc
   125701 tttaaattta gacgttattt cttgcattct ttgttgacat tctttttcca taaaatccac
   125761 cctctcttat aagtatctaa cagttgctac ttctttctgt gcagtacgtc tatatttaac
   125821 atctgggtat ccaattacta atgttgtaag aacatgatta ctacgtttta gacctaaaag
   125881 cttttttaat tttggcgaat tatttgctac atctgaaaaa tatccactaa ataaaacacc
   125941 tagaccataa gactctgcca ttaatgccat atttgatgct gcaagtgaac cactaatctt
   126001 atcttttgta attatcatta ttgcaatagg agcatgctta aagaaaaagt tatcgtcaat
   126061 ctcaacttct tttgaatatt taatagctat atttgcaata ggttttattt ttctaaaaaa
   126121 tttcactgct tcgttttcat aaattgactt tttattgtct aaaacaatat atgatacatc
   126181 ttgtgaattt ttagcactag gggtatacct acctgcctca ataatttgct ttataatttc
   126241 tgaagaaact tctttatctt taaatttacg tatacttctt ctagatttaa ttgccattag
   126301 taattcatct gaatctagct ttggcttatt tgtaagttct ataggaggtt catcaaatcc
   126361 tgtcaaggta atagcttttg tgggacatat tgctgcacaa tgtccacaca ttagacaatc
   126421 ttgtttttta attactgact ttttattttc tataattata ttgtttactg gacaatcatt
   126481 tttacaaagc ccacatccaa tgcaaagttc tttgtcaact tctattatat gttggtattt
   126541 catattcatt catctacctt tcgtttatta gtttaaacta ttataacacg tagacatttt
   126601 ttatattcat tggtaaagaa tttgattacc attaaatttt taatttctct attaaataaa
   126661 tttttcatag aattttaaaa tatcatagtt tatacataat aaaaaagaca agcttaaaac
   126721 ctaagcttgc ctttttcatc ttttattaca aagtaaattg cacttacttc ccatacttct
   126781 taacaatttt attttctaaa attttatttg tgaatcatac tattgcatca atacaatgta
   126841 aaataattct atattgattt tctatagtta aaaaagttaa aaattatact tattattaat
   126901 ttttatactc ttcttattta atacaaagtt cttatttaac atagatttct tgtctaatat
   126961 agatttctta tttaacatag atttcttgtc taatataaat cttcaccatt tgaagcaatt
   127021 actttcttat accattcaaa acttttcttt ttcattcttc ttagacttcc attaccacta
   127081 ttgtctctat ctacatatat aaatccataa cgcttttcca tttcacctgt accagcactt
   127141 actaaatcaa taggtgccca tgtagtataa cctaataaat cgaccccatc tatagaaact
   127201 gcatcatgca tagcttttat atgttctctt agataatcaa ttctgtaatc atcttctaca
   127261 taaccatttt catcagctat atctttagca cctaatccat tttctacaat aaatagtggc
   127321 ttttcatatc tatcatatac atgatttagt gtaattctca aacctaatgg gtcaattggc
   127381 catccccatt gactgtatga aagatatgga tttttagcag atgtaaatat gtttccttca
   127441 gccatatcat ctgcattttc atcggttcta acacaacggc tattgtaata tgaaaatgaa
   127501 ataaaatcta ctgtatattt attcaataat tcaatatcac caggttccat ttctggtgta
   127561 ataccttttt gctccatata ctttaacgca tagttaggat atttaccttt agattgtaca
   127621 tccacaaaga agtaattttc tctatctaac tttgtagctt cccatacatc attaggatta
   127681 caactataag gatatacact tccagctgca aacatacatc caattaagtt atttgaatca
   127741 acttcatgtg ctattttagt tgcaattgca ctagctacaa gctcatgatg ggcagcttga
   127801 tattttatct tttcaacatc ttcaccttct tcaaagcaaa taccagcacc cataaatgga
   127861 gcatgtaaaa tcatatttat ttcattgaaa gttagccagt acttcactaa tcctttatat
   127921 cttctaaaga taacattgca taatttctca tagaaaccta tcatttttcg attacgccat
   127981 gcaccatact ttttaactaa atgcattgga caatcaaagt gtgtaatagt gactaaaggc
   128041 tctattttat attttttaca ctccttaaat atattttcat aaaattgaag tcccttttca
   128101 tttggtgttt cttcatcacc ttttggaaat attcgactcc atgcaatgct cattctatat
   128161 actttaaatc ccatttcagc aaataacttt atatcttctt tataattatg atacatatca
   128221 ataccagttt tagctggata ataatgctca tcatcaaaat caaacatttt tagtttccct
   128281 gtaataactg ctgttctatc ttttcctgtt ggacatacat ctacatttgc caatcctctt
   128341 tcgtcttcat tgtatccacc ttcacattga ttggccgcag tagctcctcc ccataaaaaa
   128401 tcattcttaa aactcatagt caaagcctcc taaaattata accaaagcac tagattatgc
   128461 taatacctca atctttacta aaataagact gtaattagat tgtcttctaa ttcaatattt
   128521 ttactttctg tttctactac atctaaaaat tgtgatgaat ttgtaataac aattggagtt
   128581 acagtactat accccaactc ttttattgca tcaacatcaa agtttaatat agtttgacct
   128641 tttgtaattc tatcaccttg ttttatacat gcctcaaaac ctcttccctc taattgaata
   128701 gtatttaatc caatatgaat aagcacttca acacctgtat cagaaagaat ccctatagca
   128761 tgtagactag gaaataaggt tgtaactacc ccatctactg gagcaactac ttttccatca
   128821 ctaggtatta ttgccacccc ttgacctagt acaccagatg caaatgctgc atcctctata
   128881 tcacttaatt ttaatacttc accttttata ggacttgtta ctatttctct ttctaattta
   128941 gtagacttga cttcttttat ttcttcttta cccttatttc ttactttttt agactcttct
   129001 actttctcat ctttatataa aatcatagtt aatacaaaag ctacgaccat tgatataact
   129061 ataccagaaa gagctactat taagttaccc attcccccat ctggttcaat cattgctgga
   129121 agttcaaata ttcccattcc tccagttata aattttctaa gattaaagaa tccatagaaa
   129181 gcgcctccaa taccactagc aatacaactt attataaatg gtttctttaa aggcaataat
   129241 attccataaa ttgctggctc tgtaactcca aatataccag atataaagtt tggtattgcc
   129301 atctctttta gttttttatc tttagtcttg aaaaatattg ccaacacaac tgccgaactt
   129361 gcaaatgtac aggcaaagaa tggcatcata acattatcat atcctaaagt cataacattg
   129421 tttatatata caggaataaa tccccagtgc ataccaaaaa taacaagaat ttgccaagta
   129481 aatcctacta tagcacctgc caatagtgga ctaaaatctc ttattgaaat tacaatttgt
   129541 gaaataagtg tagaaccaaa tgttgctata gggcctataa ctataagtgc aacaggcact
   129601 gttattaata atgtaagcat tggcacaaag aaaaacttaa ctaaatttgg aacacactta
   129661 ttaaataatt tttcacacct agaagcaaaa tacactataa atataattgg tacgactgtt
   129721 ccagtataat caattgatac aattggtagt ccaaagaaat caatatatac tggtgatgca
   129781 aacattgttc ctttaaataa agtgtacatc acatctgctc ctgctgatat actgctacct
   129841 tgtatagcag gataacatac tgcagctcct agtgctaatc ccaacattgg ttttaatcca
   129901 aacttcttag ctgaagtata tcctaagaac aaaggaagga atgtaaataa tgcatctcct
   129961 gctgcattta ttaccatata accaccagat acatcactat ataatcccat tgctacaaat
   130021 aatgcattaa atcctttcaa cataccacaa gctgccatta ttcctaacac tggctgaaaa
   130081 attcctgata ttatatctat acctttatct agtatattac ctgatttttt agtttctgaa
   130141 cttgtacttg aatcatctaa accaattatt tcaactacat ctttatagac agcttcaaca
   130201 tgatttccta taactacttg atattgtcct ccacttttca ttacagtaac aataccttcc
   130261 atgtttttta atacattgtc atttgctata ctttcatctt ttaaagtaaa acgtaatctt
   130321 gtaatacagt gtactaaccc actaatattt tcttttccac caacattgtt tactatctct
   130381 tgtgctaatt gtttgtattt tcccattttt ctcctccata tttcgtttaa attaattttt
   130441 tgaaatttga aggtttggcc aactcaatgt taccatccaa ccataagtat aattttgtta
   130501 gtatcactcc tttcaatcat tcttaatata ctactgaaaa attatttcac ttacatattt
   130561 gagtctttaa ctactttagc taaatgtatt gttaaatata taagctcatc atctgttaat
   130621 atgtagttat attgtttttt aatgaaattt ttaattttaa ctacacattc aaactcttta
   130681 ttatatttag atttaataat gcttagtaat tctttgtctg tctcaccttc atgtgcacta
   130741 tctaaaagca atctttgcgc aaaaaacttt aaatgcatta taaatctata ataaaacact
   130801 gattcttcat gaaattctat cctaaaatga tacctaacta tgctaagtac ttcttgtatt
   130861 aacttcgtaa tatcagatgc caaagtatga ccttcactta actgagcatt cactatatga
   130921 aaggctataa atccagcctc atcttctggt aattttatac ctgttttgtt ttcaataata
   130981 tctagtgctt tcattccaat ttcaaactct tctttataaa atcttttaat ttcccaaagg
   131041 attgcatttt ttacatttat tccttctttc atcctttgaa ttgcagaata tgtatggtca
   131101 cttaaggata tgtaaatact ttcatttagc ttcttgttta actttatttg tgcgtattct
   131161 ataatttcac ttgataattt catgtgttct ataggaatat tattgagtaa ttcttgtagt
   131221 ttgtttgata tttctttatt tgatattcta aatactttat ttactttagt tttatctatt
   131281 agattgcctt ttgatttttg ataaccaatt cctttaccca taacgataac ttcttcatca
   131341 ttatcatcta atgtgattac aacattattg tttaatatct tattaattat catgattatc
   131401 ctccttttaa gcataaaaaa agcttatcca taataatggg catactcctt cctaggatac
   131461 tgctattatt aatgaataag cttagcttgt acttaaacaa ttactaccta attccaatta
   131521 atatgataaa acatcagaca tattttgtca actttttatt tccatatact tcatcaatct
   131581 tttgtgttgc tttttgtcag ttataataat tattcttatt aatattaatt taatagagtc
   131641 catttttaat agttttatta taatttttaa aatcaacaac attaaatcct ttatttatta
   131701 gaagattata tgttgttata tgttttaaat tatattttct ttctcacctc taaactattc
   131761 tctatctctt atttatttct gtaataaaaa acgaccttct atagtaattt aagctctcac
   131821 aataggttgt ttttcgattt ataaattcaa ttattaacct cttcatttga cttaaaatct
   131881 atactagatt tgtctcaata aaaaatttat aagtctaatt taatatttct ttgagccaat
   131941 ataaatataa aacaatttat agacaatact actaaaaatt ctattaaaat caataaataa
   132001 ttaatattat aagctctctg caacaatgaa attagtaaga atctaaatag ttcataaaaa
   132061 attgctataa gaatactttg gataattgat acaattatca tttctaataa acctattttt
   132121 atcaattttc gtttactcat tcctactcta tacataattt gataatctag tactctcctt
   132181 ataaaaataa ttatttgaga tgttagtatt agaagtatac ttgacaatga cacagcaaat
   132241 ataatattca aaagtaatga cttttgatca tcaacatatg ttttcataga ataagcaaaa
   132301 tcattatagt cttctaaatt agcatattta tcattatgta ataatttact aagtaaagtg
   132361 ttatctaact tttctttaaa aaaatatatt actggttgat ttttagataa atcaagggtt
   132421 ttaggtgaaa tattttcatt tatatttata tatcctaaat ctacaccttt attcaatgat
   132481 tttggactta aaaatcctat tactttaaag tctatcttct ttccattaat tcttaacttt
   132541 acagtatcgc ctagtttata atctattaag tatctatgaa gataattatt tataattata
   132601 ctattttctt tatcattttc tttgaaccag tttccatact ctaaatcact ttttaatatt
   132661 gtctgtttag tattgaataa gtcaacactt aagtcattta aatcattcat tacatctttt
   132721 ctattctcat atggaatttt ttcaatataa tcattaacag aaatattatt tactgactct
   132781 atactatcta ttttaattgg ataatattgg aaataatcta tatcattttc gataagtttt
   132841 ttatctgtaa ttaattttcc ttctaaagtt gtttgatata caattgaatt ttttatacta
   132901 ttatcaactt cataattgct aaacatagca aaggttattt cagatatcat aaacaacaac
   132961 aaaacaaata ttattgttat tgttaataga ctagagctaa aagcattggt tttacaatca
   133021 ttattaagat atataaaagt aatcgagtat tttcccttaa taattttttt aattaaacat
   133081 accattttta ataatgcata tatcaaactg tataccaata aatctagtag tattaatcct
   133141 aaaataaaaa aaatacctag aaaggacttc acatatattg taaaagaaat acttgttaaa
   133201 aatattacaa gaattatatc tggaataaag ttaaatttat atgaagacaa catactatta
   133261 tctctattta ttccttcata aggtattttt ttaacaaaac ttataggaat taatgagaat
   133321 attgatgttt caattattat aataactatt gaaatgaaaa tatttttgat aatactcaaa
   133381 atagaaatat taaatagatt aatatgttgt aagttaatat agaatatagt tataggaatc
   133441 cccaaaataa tacctattat aatccccttt atagtaattg acataagttc agtaaatact
   133501 aaaaaagata aacttctttt tttaattcct aaagccttaa aagttgaaaa atcatgtatt
   133561 cgatttaaaa taaatacaat aaatgtagaa catagacaaa ttccagtgat taataatgaa
   133621 atagctccaa ttaaatttat tgaatctaat tgcatagata ttctctttat tattgactgt
   133681 tctagttcat cagttgttct aacttcaaaa tggtttttaa atacattttt tatttcattt
   133741 ttaatatttt tcacattttc tttgtttatt atatttatat aagctacatt atatttagtt
   133801 tcattaggca aatatacata actttctcca actacctctt ggccaacctc tgcttctttt
   133861 tgagctgtac ttaatgaaaa cttttttggt attatatcac taactttaaa atatgtatca
   133921 tcataaactg aagaatgtag ttttaaaaac actttatctc ctatatttac atttaattta
   133981 ttagctgttt tttgggataa aactatatct ttttcatttc ttaattttaa atatgtattt
   134041 tgcattttta tattatttac tacagtcaat tcagtacttt caatcatacc atttgacaat
   134101 atatttgtat tcatactact tcccaactga aaatcaatag cttctttatc ttttaattct
   134161 tctaacttat ctatttgttc acttgtaaag tagtatttat tatattctat attttgtatt
   134221 tttatatctc caccatttgt tatagccata tttctcttaa cttcacttga atatgtatcc
   134281 gttaacactc ttgtaaaaag taatattgct gtggcaaata caatagatat tatacaagag
   134341 atttttaata atttattatt cttcaaacta ttcttactat atattttata aacttcatga
   134401 aatatcaatg tatcaccacc tattttataa tagttccatc tttaatactt ataatcctat
   134461 cactatattc tgccatttga atatcatgag taaccattac tattgtagta ccatattcat
   134521 tgtttatatt cttaaacaat ttcattatag catgactatt agtactatct aatgatccag
   134581 ttggttcatc agcaaagagt atatttggag aacaaactag agctcttgaa atagcaactc
   134641 tttgcttctc accacctgat aattgtttaa tattattttt tgtttttgat gtcaacccaa
   134701 cctttttaat catcttatct actattttat aatctttatt atcagaaaaa atcaatggca
   134761 attttatatt ttcttcaaca gacattgatg taattaagtt aaatgattga aatacaatcc
   134821 ctatctttct atttctatat tcagcaagtt catcatcagt taatttcgat aaattctcac
   134881 cacaaacttt cacgtttcca gtataatttt tatcaagacc acttaatata cttattagag
   134941 agcttttccc actaccacta gcacccatta tagaaacaaa ttctccttct tctatgtata
   135001 aatctatatt ccttagtata gtaagttctg tgtttaacaa gtctacaact ttagataagt
   135061 ttgaaacttc aattatcatt tttttcatac cattatttcc tttcatacaa aacttttaag
   135121 attgattatt aattaaaaca gagtatatag gacacaaaat attagagaaa cttatacaag
   135181 caagcttttt tgagaatgat atattttcta aaactgtaca aatcttaata ggtcattata
   135241 tttcttatta tacataagat tgcttgacca aaagttagta aaattataaa aaataaactt
   135301 tttcaatgat aaatctaaaa aatataatat catcaataat tcggaagtgg gatttaattt
   135361 aatactaagt tttagcttag atatacagaa tctctcccca aaatttatat atttataaca
   135421 ctttatgtta taaatatatg actctttcaa ataaatttca acagaatatt gcgaatactt
   135481 gatatcatct tataagtata atttataaaa aatttcatga taaatattta agaattacag
   135541 atactattat aaaactactt ttttattaca ttttatagaa ctctccacat aaaaaatgct
   135601 tataacttat gacataaaat gattctttaa taaacattac aatacaaggc taaactattc
   135661 tattaatcat attatttatt aaccaccatc ctaatggact aataactttt acatgtacaa
   135721 ttttatacat tataaatcct atagtacacc caagagacca tcttcctgta gtaggaatat
   135781 aggtatcaaa tttcttctcc aaaataaaaa atatgccaaa ccttaacaaa acatattttt
   135841 atatatttta ctaaagtttg actatttaag aatcgtattt tttaaagttt taaattgagc
   135901 ttatcttaat tattatataa ctattattta ctaagtttta taggttaatc acttttatta
   135961 taaatattta tcatgaattt ttttatctca tactatttaa cacacttcct taatttacct
   136021 ataccttcct taacattttt ttcaactcca aaaacatatg tcataataaa tggagcaacc
   136081 aatgctataa atataactat aagtccattt actatatttg aaatcccctt ttcccctgat
   136141 aatccaagta ctgccattat actattttgt ggaacatata aagtcacatg agtaattcct
   136201 gcaaataacc ctgcgattcc tgctcctata gatgctaaca tagcaggttt tttaagtttc
   136261 aatgtaactc cataaagagc tggttcagtt atacccatga tagctgatat ccatgcagct
   136321 gatgctaact gtttcatctt actatctttg cttcttaatg ctacagctaa tgtcgcgcca
   136381 ccttgcgcta aattagcaca aacttgagat attaatatta gcgattcttg tcctgtagtt
   136441 gcaaatgctg atatgaatat aggagtcaat gcatgatgca tccctgtcat aacgataaat
   136501 ggcattgcag ctgctaataa acaaaccatt ataaatccta accttccttg tagtaaattt
   136561 attatactag ctaatccctc tcctaagaaa tttcctattg gtccaattac tattaatgct
   136621 attggcgcac ttattaataa tactaaagtt ggatttaaaa ttgtttttaa catgctaggt
   136681 gttaatttat caatgaattt ttctatatat gacatcatcc atactgttaa aagtgcaggg
   136741 ataacagatg ctgcatatat aacaccttga attggtactc ctataaatga tatagggtcc
   136801 ccacttgata cccatgcaga gaaatttgga tgtaaaaaca cacctactac tataactgct
   136861 attgatgtat taacattaaa ttttttagct gcatttattg caagtattat aggcataaag
   136921 taaaatgcta catctcctat tatatctaat actctatatg tacttgaatt tgatgatagc
   136981 caattaaaag tggtacaaag agataatata acttttatca tcccagatgc tgtaagggct
   137041 ggtatcatag gtgtcataca accagttatt gtatctatta tattatttaa aatactattt
   137101 tttttatttt tattttttat atcgctttta atatctcctg tggtatttat ccccttattt
   137161 attattgcat taaatacaac acctacctca ttacctatta tgacctgata ttgagttgaa
   137221 gttgagttta ctccaactac cttatctata gattttaatt tatctgcatt gactttcttt
   137281 tcatctttta agatgaacct taatcgtgtc atacaatgag ttaagtcaat tatattatct
   137341 tttcctccaa gtccatcaat tatcaattga gctacatctt catatttatt cttcatacct
   137401 tatcctctct tttaaaataa tttttaatat agttttaagc caaattaatc tttttactcc
   137461 aagcttgtaa tagtgtattg taatttaata agctagtatc ttctacaata tggtcacatt
   137521 ttcctagtac ttcttttttc cccacaccaa ttgatgtcat attggcagaa tttatagctt
   137581 taatacccga ataagaatct tctattccta cacaatcata ttgttttaaa tttagaatct
   137641 tgctcccttc aataaaaata tcaggatatg gttttcccct ttctaataag gatggattta
   137701 ctatacaatc aaattcatct tttattccca aagattctaa tatcctatgt gcattcttac
   137761 tagcagatgc tattcccaat ttcacattat tttttttaag ttcttttata agctcattta
   137821 tccctggtaa tatatcttta tatgttaatg agtttattaa ctttatataa atgttatttt
   137881 tttcttcaca cacctttaac ttttcctctt tagtataact atctacttta ttagcagata
   137941 acaatatttt atctaatgat tcttccctgc ttatgccttt taatttttca ttaaaagttt
   138001 catctatttc tatatctagc gattttgcta tctcatgcca agcttcaaaa tgatacttag
   138061 cagtatctgt tataactcca tcaagatcaa ataagactgc tttcatatta attactccct
   138121 ttaaaacaat tattaacttc tattatgttc tttgataatt ttatttcttt attatcatgt
   138181 aatatggtta tatttctacc tttgattaac ttataataag atttatattc ttctatattt
   138241 acagaaacta aattatctct aaataatata ttaaatttaa tatttttcca gtgtttaggt
   138301 atccttggtt caaaacttaa tttatcattt tttattttca ttcctgcaaa tccatatact
   138361 aaactcatcc atgttccacc catattagta gcatgtattc catcacttgt atttttttgt
   138421 aggttattaa tatccattaa tgctgtgtcc ataaaatagt tataagcttt ttcatgattt
   138481 ccaatttcac ttgccatcat tccaaatatt gaccttgaca aagatgaatc atgagtagtt
   138541 attttttcat agtattcaaa atctctcttc ttttgttcta agctaaactc atcagggaaa
   138601 agcaacgctg aaagtacagt atctgcttgt ttatttactt gatatctata tattgttaat
   138661 ggatgataat gaagaagtaa tggatatttt tcttttggtg tatttttaaa atcccatact
   138721 gatttttcta aaaatgaatc gtcttgttta cttattttct tctcttcatc atatggtaaa
   138781 tacatatttt gagcggcatt tatccagttt ttcacttcat attcttgtaa tttaactttt
   138841 ctaaatactt catttgaaaa taaattatgc ttaaatttat ctaccatctg tactgcatat
   138901 attaaattat atttagccat taaattagtg tagtaattat tgtttactat tgctgtatat
   138961 tcatctggtc ctgttactcc atttatacag aatttattat tttttgattc tatataatct
   139021 ccaagttcaa cccaaaatct tgctgtttct ataagaattt ctaagccatt ttgcatcata
   139081 aattcttcat cattagttgc ttcaaaatac gttctaatac cataagctat atctgcattt
   139141 atatgaaact gtgctgttcc tgctggataa tatgcactgc attcattacc atttatagtt
   139201 ctccatgaat ataagcaacc tttatttatt ccaagttctc tagctctttt tcttgatgca
   139261 tctaagattg agtatctata atctaataaa gctctagcaa tggatggttg agtatatata
   139321 aaaaatggta atatatacat ttctgtatcc cagaaataat gcccctcata gccatcacct
   139381 gtaagacctt ttgctgatat attagtcttt ccatctcttc ctgctgattg ataaatatga
   139441 aataaattgg tttttatccc cagttgaaga gttttatcgc cttcaatttc tacatcagag
   139501 gttgtccaaa actcattcat tttctttctc tgaatatttt tgactttatc aaatccaata
   139561 ttacatgctt ctcttaaaac caattctaat gattttaaat gtgcttctga ttctaaacat
   139621 tttaacgact ccagacattc taatgatttt aaacgttctt catttagatt taaatcagaa
   139681 tatactctac tatagcctac aacaatttct aaatttaacc tttcatcttt tttggcatag
   139741 acttctattt ctcgctcaat acattcatct gaaacattat aggtctcatt tgtaatattt
   139801 ccacaagtaa tatatgaatc aaacccacac cataacccta atctacttct ttctgtaact
   139861 aaattcataa aatacttatt gttatatttt tttacatcaa ttttaaattg cttcttattt
   139921 atagatgcca ctcttgggtc atctactttt tcacaattaa acttctccat actattttcc
   139981 attttatttt taaattttat ttttccatta aaattcaatg gtgttattgt atatgaaatc
   140041 atcattaatt cttctatatc ttgtgatact aatctttcta tagatacttt aacttttcta
   140101 ccacaagagt tttcccatat aaatgaacgt ttaagaatcc cttcatttaa atctagtatc
   140161 ctagtatgtt cacttgtaat accttttgat aaatcaaaat aatctccttc aatagagaaa
   140221 tttactatat gagcattagg taacttacag atagtctgat tttgttttgc atagccataa
   140281 gcgctttctc catatgtaat tggagattct tcataaaatc catttacata tgtacccata
   140341 ttatctacat actcattatt aaaatcagac tcttcaatat tccctctaac ccctaaatgt
   140401 ccattagcta gtgtaaacaa cgtttcattg gattttattg tatccttact aaacccttgc
   140461 tctataagtt ggtccttagt agtaaatatt aaactcataa taacactcct ttcttaaaat
   140521 gaattatgca tgagtttcca tatcattaaa taaaatttct ccatctgttt ctattacttt
   140581 tttataccaa aaagcacttt gttttttagt tcttttaaat gagcctcttc catagtcatc
   140641 agaatcaaca tgaattatgc catatcgttt tgtcatcttt ccttcactta cactggttac
   140701 atctatacat ccccacataa gatatcctat aagctctatt ccatcttcat ttactccaag
   140761 aatcatattt ttaatatgtt ctttcatgta atctatacga taatcatcaa ttatttttcc
   140821 atcttcattt acaatatctt gagtacccag tccattttct actataaata aaggtaactg
   140881 atacctttca tataactgat tcatagttat tcttaaccct acagggtcgt tttgccatac
   140941 actatttgat tttggaagat atggattttt tatggtttct ggtccgtttg cctttgattt
   141001 ttctaaacct tcagctctag ctgaactaca agcactagaa taatagctaa aagatacaaa
   141061 atctacagta ttatccttaa gtgttgataa atcttcctct tttattatta attttatttg
   141121 atttgatttt aaataataac tcataaagct tggatacaca cccctaactt gaacatcaga
   141181 aaaaaacaaa ttatgccttt catgctctaa agttgcaaat acatcttctg gtttacatgt
   141241 gtatggatat gtttttccag cagctaacat acacccaaac ttaaattctt tatttatata
   141301 ccttcctatt tctatagttt ttgcattagc taataattga tggtgtgctg cttgatattt
   141361 tttctgaagt tgattttcat cagctataaa agttaaccca gcacctatat atggaatatg
   141421 cattatcata ttcatttcgt taaaaggaat ccagtatttg acatcatctt tatatctttt
   141481 catcaaaatt tcagcatatt ttacatataa attaaccact cttctatcag cccacccaga
   141541 atatttttca actagagaat aaggtatatc aaagtggctt atcgttatta atggctctat
   141601 attatatttt tttaattctt ttattatatt atcataaagt tgtaatccct tttcatttgg
   141661 ttcactttct tctcctgttg ggaatattct tgaccaagat atagaaaatc taaaacattt
   141721 aaaacctatt tctgctaaca ttgctatatc ttctttgtaa ttttcacaaa atttaatccc
   141781 tatatgactt ggatagtatt gattattttc atttaaaata ttatcctcat ctaaacatac
   141841 atcttttaat ctcttatcat ttaatggtag tttatcaaac tgagataaac cttttccccc
   141901 atctaaataa aatccttcac tttgattggc tgaaattgcc cctccccata aaaaatcttt
   141961 ccctaatttc atgcatctac ctctttcaca atataaagtt ttataatttc tatctcatat
   142021 ttagttataa gatttttttc atactatacc ttttaaataa ttcaatttaa aaatccaatt
   142081 atatttttta ctcactataa ttaatattgt ctattttcaa tactttcata ttaaatatca
   142141 atattagata tctatgtata taattatata tatagcaaat acatttttat atcctcatta
   142201 ttgttatctt attctcatat attgctgtat atttatatat ataaaaggat ttatttcgaa
   142261 atagaggttg tattgagaac taaaatttag actttataaa tgaatggaat tttcattgtt
   142321 gaaatactga aaatatattt gatttcatat aaaagaaagt gcctcatgaa ctaagttcat
   142381 tttgagacac tccctttttt ctccaagcta ttatatcttt ttttaaattc taatggagag
   142441 actccaattt tttctttaaa tactctgtaa aaagtttttg tacttccaaa accaacttct
   142501 tcaaccaaat ctacaatgga tatattgtta ttaagtaata tccactttgc tttttctaat
   142561 ctatattcat ttaaaaaagt tataaatgtt tttcctgtat tttttttgaa aaatttagta
   142621 aaataatata cactaaatcc tacttcataa gacacatctt ctaattttat aggttgttta
   142681 taattttttt ctacatattt gaatatattg ttcaatctct ctaatatctc tttagagttt
   142741 atttcatatt ctactgtatt ttcttcaatt tctctaggaa tctgtctata taatatagga
   142801 attaaattat acattttacc ttttattgca taactatatc cttctatttt gtataggtct
   142861 tcattgtaga tatctatcaa tatatcgaaa actgactttc ttatttttgc tgaccaatct
   142921 ctactacatt tttttatact actgaataaa ttaattaagc tttctttttc ctcatttaat
   142981 aaaattaaat cattaaaaaa agatatatca aattgaaata ctaatctttc acttcccggt
   143041 gatggcagta tataatgaat atctcctcct tttattatca ctatctcgcc tttttttaat
   143101 tgcataggct tgtcatttat aaatagattt actacacctt ctgttataag taatatttct
   143161 atttccttat gccagtgtgg tgttgttaat acttctcctt catttgatag actacgaaaa
   143221 ggaaattcat gtattaattt aggcatttct aaatatattg ccatatatat cctctcctct
   143281 ctagtgtcta aaaattaatc tatactattt aaaagaatac acattttatt ttaaaaacct
   143341 caaatttata atttatacaa tacctacact tcataaaata tatctaatat ttcttttttt
   143401 gtatgtgcat ttaaaagtct ttcacctata tttttaccac ctaaaatgta agctatttta
   143461 gatattaata tcatatcttc attgcctcca gattgtggca tagcaaacat aattattact
   143521 tttacaggta agccatctat acttggccaa tctacacctt ttttagattt acctattact
   143581 acagaggcct tctttacata ttttgttttt ccatgtggca tggccatttg ataacctata
   143641 ctagtagagc ctattttttc tctatgtttt aatgccttta taaacttact ttttaaagtt
   143701 atacttcctg tatcgtataa tttatctact aattcctgta ttatgccttc ttttgtagtt
   143761 gatttcaaat ctaaaataat gctttcttct gttaatattt ctctaatttc catttgtttt
   143821 ctccaataga ttattcttaa ataatatttt aatatcctct ttgctcttgc aatctattat
   143881 atagtttata tagttctttt gcctatataa atttgatatt tccattaaaa tattctttaa
   143941 aaaactttga ttactaattt ctaaataaat atcaatcgtt ctagtaacat tattgatatt
   144001 cattatccct ttatttaatt tactttgctt atgtatatat atatttaaat cttttcctaa
   144061 tgaaatagat tcatatttac tccctaaatt cacacctatt aaactttcca tctgagctgc
   144121 atcaaaatta aaatatatat tatcttctaa atacattcct aataagtttg tatctaagtt
   144181 catacttttt ttaggtttag aaagtaaagc attttttata ttattaatat cattttccat
   144241 taatagtact gatacaacta tatgtaattt atctttcaaa tctaagttta cagtagatat
   144301 tacaaagtct acatcatcta aatttcgctt actcaactga tgcataggaa ctatatcaac
   144361 tatagtccat tcaggaaatt ctctttttaa tctggctgca aggagctgag atgttccata
   144421 tcctgtatga caaactacta ttactctttt actactcata tttctttcta ttgccgcttg
   144481 aaaatatgtg gcaagatacg agacttcatc tatactaata ttcttcaaat tatcatactc
   144541 tgtcataata tttatagtca tcatacataa tcccagcaca tctgaaaatc gctcttgtat
   144601 ctctcctaac aacgggtttt ttatttggat atcatatctt aatctgttta acataggcct
   144661 tacatgagat gctagacttt tctgtagtaa gtcatcattt ttgagattta tatttaaaaa
   144721 tcgtgacata ttctctatca ttatagatga aactttttca ctttcactta atctatctga
   144781 ttcatcattg taactactat tactttcgct actaaatcca gatgatacca aaaaaatata
   144841 tatgtacata agttcatctt tcgttatttt tactctgtat ctattttcta ttttatctat
   144901 aagtgtagtg acatttttat atactaactc gtccaaatta tctacagaaa tttctctttc
   144961 ttcctgagat tctatttgat taccttcttc gattctcttt aaacatataa gtatatgggt
   145021 aattaaattt atatagtagg gctgatttat agtatatcct aaattgtatt ctaattctgt
   145081 aattatagtt tctacaaata taatagaatc aatatcaaat aaatttatca atgcactaaa
   145141 tgtagcagaa tctaatcttg ttaactcaga tatatcatgt tgttcataat tttcatctaa
   145201 taaatcatcc atcattttgg caatcgattt ccttatatcc acttctttac ctataatctt
   145261 agttccttct aaagttttat taagttttaa attgtattct tttatccatg cctctatata
   145321 tttaaaatca tttactatag aagttttact tacataatat ttatctgcta actgatttat
   145381 tgaagttata ttatttgaat ttagtaataa atactttaaa atctccattc ttctctgctc
   145441 tactgataaa gatttatttt ccttcgattg tatatttaaa ctattaatta agtctatgtt
   145501 cttctttgct aaatcttcta ttaatattcc atagcctctt tttatatcaa tttttatatt
   145561 aaaagtttct aaatatttct caatcatctt caaatctttt tgtaaagttt tatcagatac
   145621 atttaattta tctttaaagt attttatagg tctatattta ttttcgttta gtatcaattt
   145681 aagaaattca atttgcctcg acacaagcat acttagccct ccctacctat gtttatatat
   145741 ttctatgttt atattaagta ctattttaac atatttacta actatgtaaa attactaaga
   145801 tacttctgta tcataaaaga atttatgata caccttacta aattgatata atagataata
   145861 taatttcaaa ataaaaatta aggatattta gaagtagtta actgattcta aatatcctta
   145921 ttattattct atatacttgt tgttattcca ttaattattt ttactattat ttataattta
   145981 agcaccaagt aattcaactt cactattttc actccttata gtaggctttg ttacccctat
   146041 aatcaatgct gttattactg taccaatcaa tatacaagct atatatgcaa ctggtgcact
   146101 acatgcaaat ggtattacaa atattccccc atgtggtgcc attaaagtta tatctaaact
   146161 catacatatt gccccaccta tacaagaacc aattatattt gctggaatca ttcttaatgg
   146221 gtctgcagct gcaaacggta ttgcgccttc tgttatgaaa gatgccccca ttatagcagt
   146281 tggtagagat gactttcttt cttctttagt aaacttattt ttgaatatta acatagctaa
   146341 tgatattgct aatggaggta ccattcctcc taccattaat gctgctgatg gttcaaatat
   146401 attacttgaa aacatagcca atccaaaagc tgaagctgtt ttattaatag gtcctcccat
   146461 atctgatgcc atcatccctg ctaatattgc acctaataat actttattag ttccagacat
   146521 actttgtaac caagattgta aagcttcatt taaccatgat gctggcgtat taactacaaa
   146581 gaacattata gctccactcg taaatgcaat caaaagtgga catatcaata cagcatttac
   146641 tccttttaat acatctggta aattttctgt tatcttcatt actcctaaag ctatatatcc
   146701 tgttgcaaaa ccagctacca taccacctat aaaccctgaa cctccaataa ctgccataaa
   146761 accagctatc atagcaggag caaatccttg tcttcctgct attgatttag ctataaaacc
   146821 agcaagtatc ggtataaata acttaaatgc tgaatcgcct ccaagttgtc caaagaatcc
   146881 agctataggg ttgtatgttt catgagttgg gtctgatgca aatataccaa acataaaagc
   146941 tatggctata ccaattccac ctatcactac aaatggaatc atttcagata caccactcat
   147001 taagtgctta taaacaccct ttttctctga cccttgaagc atttcttttg aatcttctaa
   147061 agtctttcca cctggtttaa tttctttagc cattccattt tcagcgttta taattaaatt
   147121 tttagctaat gaaacattct tagcatctac tactttcttt tgtagcactt tctttcctat
   147181 aaatctactc agttgaactt ctttatcaca agctattatt acgtattcag ctctttttat
   147241 atcttcttta gtcaacttat tttctacacc tatagctcca tgagtttcta ttttaacttc
   147301 atatccaagt tcttgccctg cttcctctaa tgcttttttt gccataaaag tatgagctat
   147361 acctgttgga catcctgtta tcccaactat aagaccttta ttttgattat tactaaaatc
   147421 tcctaattct gcagctttat tattaaatat acttaatatt tcgtatggag tttctgcact
   147481 tagtagatgc ttaagaaaat tttcttccat tagatatgta gctagtttag atataatctt
   147541 aagatgttca tctgaacctg attctggaac tgctatcata aaaaatgacc taagtttttg
   147601 accatcatta tctgtaatct ctctatctgt tcttaaatac atcattacag gttgatttac
   147661 tacatttgac ttagcatgag gtatagctat taaattaccc atattagttg atgattcttt
   147721 ttcgcgttta ttaatatcag ctataaactt ttctttatta tttatataat ttccatggta
   147781 caaatgattt gccatataat taattacatc tttttttgtt tgtaattgtt tatctagtac
   147841 aatacaatcg cttcgtagta ttttacctat cataaattct cccctccttt taatttgtta
   147901 cctcataatt aatttttatt tttataaaag cactttaact tatctatagc attgaataga
   147961 ttcattttaa actctataac ttctcttgca gattttatac atggtggata tatagtatct
   148021 ggctcatata agcttgggtt ttgttctaat agttctctgc acttcttata atatgccgac
   148081 ttaacatcac tcgaaatatt tattttacaa actcctagtt taactgcttg tgctatttct
   148141 tcatctggat ttgatgaacc accatgaaga actaaaggta tatctactac ttctcttatt
   148201 tcttttaata aatctagttt aagctctggt ttaaaacctt ttggatatat accatgtgct
   148261 gtaccaattg caatagctag tgtgtctact cctgtttttt caacaaaatc cttagctaat
   148321 tttgaatctg tatatattat ttcatcagta ccaccttcac ttgatgttcc tgttgttcct
   148381 attgttccaa gttctccttc tacggacaca tttaatcctt ttgctatttc tactatttcc
   148441 ctagatatag ctacattctc ttcatatggt aaatgtgagc catcaatcat tactgatgta
   148501 aatccacatc ttattgccct taatatttgt tctttatttt ccccatgatc taagtgtatt
   148561 accataggta ctttactctt atttgcttct tctatgcaac tagctacaaa gctatctcct
   148621 agaaaactta gctcatttgg gtgtattgca agtattactg gtgcattttt ttcgttagca
   148681 ctctgtacta ctgctttaag tatttgccca cttcctatat taaatgctgg tacagcaaat
   148741 tgattttctt gtgccacttt tagcatttcc ttcatattta ttaacatatt gtacctcccg
   148801 atattttaaa ttttaggttg aatttgcttc ttgttaattt tgttgttgtt tatatttaaa
   148861 taatatcagg gtaatgaaga tcagaaaata acaatcgttt tccttagtga aaaggaactt
   148921 ttattataca ctctaagttc cttttcacta aataattttt agaagtctgc atcatagtta
   148981 attatatttc tcatgtacat cttctctttt taagtgtttt atgctttagc cttcatagat
   149041 tttataataa acaattaaga tacattaact ataaatttaa agatactcat gcaatagtta
   149101 atgctatatt agagtcaaaa aaattaaaaa gatattagct atttggccaa taccttttct
   149161 tggattccaa tagtatatac gatttataga aatcatactc acgattatct aatgttttac
   149221 ttccataaac tttacataaa acaccaaagt gacaccctcc aaattcatct ctagctaata
   149281 aagtgattta gttttctaag caccaattta taaattagcc tttgttatct tatgtaaatc
   149341 tttttctatc taatttaaaa attattccta atgctatata gcatatacca attactaata
   149401 caccataatc catagatact cctatcttaa attcttgcat attagttaca atagaaattg
   149461 aaataggttt attacaaaca ccataaagca aggctgacat tgtatattat ccaattgtat
   149521 gaatgaatac taatatagct ccttttaatt aaatgatgct atataaatca tatttatccc
   149581 aatttttaat ctaacctatt tatatgtata ttccttttta ataaaaaaag atattgacta
   149641 aatagtcaat atcttttagt tgatttaaat acccacaatt ttaatctaat ttttaagtgt
   149701 ttccttaaca taatcttata aatattaaaa tttatctacc tataaaattt ctccattaaa
   149761 ttttattaca ttttatctta aaacaattat aatctgacct taatcacatg ttatattata
   149821 taaatatttt taacaaactt aataattaaa taactatatt ttattatcca tcttataaat
   149881 gtttataaat tttccactat tcttcttcaa taaattcaaa caaattttct actgtagtat
   149941 cgaatacttt agcgatatcc atagctaatt tcaaagaagg attatatttc ccattttcta
   150001 agtgtacaat agtctcacgt cttaccccaa ccaatttagc aagttcattt tgcgtcataa
   150061 ggagtttttc tctgtattct ttaatttttg ttttcatcaa tattgccact tagttacata
   150121 tccccctttt atcaaagtat atatacaaca ctaatttaga taaagactgt ataaataaaa
   150181 ctgcaatgag gattatacct gtatctaggt ttgatatatt tatattactt gtataaggtg
   150241 ttgcaaagaa aatagatatt attactatag aatatatcat tatttttatt gcaatcttat
   150301 taacctttga taatataaat tcagatgatt catcaactaa atcattatat tttttattat
   150361 aaattgaata acatccaaaa actattaacc aactcaaccc tggaagagaa gcagtgcttg
   150421 gacctttaaa aatatactta gtggctaata cagctataaa aaaataagtt attacaagca
   150481 actccaggat aagctttgat cttacaccag tttctgattt agacatataa aatcactcct
   150541 taaaaattat attctctata ctctttaatt ttcgttttta tcaatattat cacttagttg
   150601 catattccct ttctatcaaa atgtatatac aaaattaatt tagataaaga ttgtataaat
   150661 aaaatagcta agagaattac acctatatcc aaatttgata tatccaaacc tcttgtataa
   150721 tttgctgaaa agaaaacaga tattagcaaa atagaatata acattatttt tgatgcaata
   150781 tgatcaacct ttaataacat aagttttgac gcctcgtcaa ctaaatcatt atatttttta
   150841 ttatacatga agtcacatgc ccaaaaagcg aataaaatta taaaagtaat acaaagattt
   150901 ccctctttaa aaataaactt ttttaataat gagtctataa aaaaatagga tatcataagt
   150961 aactctgaaa caagatttgt tttaacacca agctctgatt tagacatata aaatcacccc
   151021 ttaaaagtta tatatttata acaccttatg ttataaatat ataacttttc caaataaatt
   151081 gcaatagaat attgaaaata ttcaataata tcttcataaa tatattttat aaaaggtttt
   151141 ataataaaca ttacaataca gtactaaatt agtttatttc atctatcatc tcaatcatat
   151201 catttactaa ctattattct aatgagcata taacattgaa atttataatt atacaaccta
   151261 aatgcctccc aatgtaccct caaaacctca ttttctgtaa ctgaagtata attggtatat
   151321 tttatcactg aaataaaaaa acactagtca ataaagacta gtattttcaa gtattttatc
   151381 attctttttt taattattgg agacgaatca tcagaataat accataattt atctatatgc
   151441 aaattctaaa tttaaaataa agtttcagat aaatttacta ttctatgcta tgatacaaca
   151501 gaaaaaactg aaatctatga gtggtagctt catataatcc tagttcctac agtaatcaaa
   151561 actgaggttt attctatatg taactaatga taaattttat tataggagtt attagctcta
   151621 tttgtgttac tataagtagt aattatatat atgataattt tttaacactt ttctgttggc
   151681 tatatagaaa gtggtttaga atttaaattt aaataaaatt taaattcacc aaaaagaaat
   151741 ctatattaga aaccactact ctattccacc agattgtaat tttttgttct ttatatcaca
   151801 atgctatacc atattaaatt gaaaaataaa ttttaaattt atttgttaca attcattagt
   151861 tcaaaaaaat attttgagtc atgagttttg taaagattta gccatgaatt taatgcttct
   151921 gattcaaaaa catctaaaag tttcagtact tgaaacgtaa attccaacgg agcaattcct
   151981 gaagccgtaa ctaaattttc atcactaact acagattctg ttttataata tttttctcca
   152041 gagtaatttg gtattaccat tttaagaaac tctaagtcat tacttgtatg atttctaaaa
   152101 tctaatagcc cttttttagc taggcctaat gtagctccac atatggctgc aactatagaa
   152161 tcttgtatta aagcttcttt aactttttct aatattatct catgattcat agataaccaa
   152221 gtatttcccc ctggcaaaat taataaatcc ttactttcca tattaaactc atcaactgta
   152281 atttcaggta aaacttttaa cccacccatt gttataatag gatttttatc aattcctaca
   152341 gtaattactt ttagtggctt taatcctttt ttaaaatatc ttcctgtatt taattcagca
   152401 gttaaatatg ccacttccca atctgacata gtatcaaata catacatata tacttttcta
   152461 tttttcatct tttttactcc ttatgtaatt aatttatata tctaattata aaataactta
   152521 actgacatat tcagtcagtt aagctattaa atttgataat aatcaattaa ttctagtaaa
   152581 tcttcaatta ttttcttcct aaggcttagt ggttcaatta cttgtattgt ctttctataa
   152641 ggtaaaagta tatttggtat gtacttgcat attacttcct cttcaagcat aaatattatt
   152701 ttattaggtg ttctttcttt caagtagtgc cctaaaaacc aatgttggct taaactatct
   152761 aaagaatcta tactcccttc tacaactaat tgaattatat tttgttcatc ttttatttca
   152821 ggtataattc cttttataaa aaattcactt gctgaaaatt ctgtcggtct gttaaatgta
   152881 tttgatgttt ctatgatttc actaatccta tccactctga aactacgtac ctcatttctc
   152941 atattacaaa atgcaactac gtaccaatta ttattccagt gaacaattcc atatggattt
   153001 ataattctat attttgattt tgctttacga cctgcatggt agttgatttc tacagatagc
   153061 tcctttaata tactattctc caatttttta agtactgatt ctatagacac tttcccaatt
   153121 ggttttatta cttcaagggc tcttaagttg tttgttaaaa tatcttcttg tttttgattt
   153181 gaatacattt ttaactttaa tatcgattta tctaatgctt cgtctaagaa gtatccttct
   153241 tttttagcaa atagagctgc atgaagtaga gatttttgct cttctatatc aaaaaaaaga
   153301 ggtgctttag taaaattatt taaaaggcta tacccaccat tatgacctgt atctgaaatt
   153361 ataggtactc cactcgcaga aagtacatca atatatcggt acactgttct tatatttatt
   153421 tctaattttt cagctatctg ttttgctgta atttttttgt cagagtttaa catccacagt
   153481 atagacatca tattgtcaat tttagccatg tagtttcacc tctttctatt tgttatataa
   153541 agttattata taactttttg attgattttt tacaaaaaaa cattagtaaa ctgctaataa
   153601 tttatactaa gatttatttc aaatatttat agagagtctt tttctatagt taagttatcc
   153661 attaaattcc atagtagtgt atctacttca attgatatat tttcaactac acttctcgtt
   153721 atatatcaat tttctttttt aaagatttta caactgatat ttagttcaag atttatatat
   153781 attctttttc aaaaaccttt cagtctcaaa ttaaaacttt tttgttttaa tttcttcaag
   153841 atatagaaaa agtcttatcc taatttattt aagctaaaat tcttatattt taaatttttc
   153901 tttaaaacta aaatatttat catcatcttc agcaacaata taaatctact aattaaatac
   153961 ctaatattta ttcatatttt tctaaacata attactaaaa ttgaattaat gatatcaatt
   154021 ccatcaatct cttttaataa aaaattctct tttttatatg aaaattattt caaaacttta
   154081 aaattaaata taaaaataac tataaataga tttttattta cacaaatcta tctatagcca
   154141 ctatagttta tccaataaaa taataaaata aatatgtaca caataaatgt tatttacgtc
   154201 ttaagtattt atttattaga tttttaatta aaaaaaacaa gctagtgaac attaatgcta
   154261 aatctagcat tatattgctt tgatctcctg tttgtacatt ttgacctaca ttactatcta
   154321 aactttcatc tgtatctata tttatatctg gttttccatc cccatctgta tctatattta
   154381 tatccggttt cccatctcca tctatatcta tatttacatc cggctttcca tctccatcta
   154441 tatctatatt tacatctggt tttccatctc catctgtatc tatatttata tctggttttc
   154501 catctccatc tgtgtctata tttatattcg gttttccatc cccatctgta tctatatcta
   154561 tatctatatc tggtttgcta tttcctccat tatctgggtc tggtttacta tttccaccgt
   154621 tatctggatc cggtttgtta tttcctccat tatctggatc tggtttacca ttgccaccgt
   154681 tatctggatc tggtttacca ttgccaccgt tatctggatc tggtttgcta tttcctccat
   154741 tacctgaatc cggtttgcta tttcctccat tacctgaatc cggtttgcta tttcctccat
   154801 tacctgaatc tggtttgcta tttcctccat tatctggatc cggcttgcta tttcctccat
   154861 tatctggatc cggcttgcta tttcctccat tatctggatc tggcttattt agatttggat
   154921 tacctgtatc ataacctcct gagccagtat ctacattttt atcaggcttc caataatcat
   154981 ctactccatc attatctgta tctattgctg gacgattata atctgtatca gggtttccat
   155041 ctccattggt atctatattt ttatcaggtt tccaaatacc atctccattt ccaccttctg
   155101 tactaggctt ccattcacct gtattatcag tatctatgtt aatatctggc ttccaatcac
   155161 cactcgtatc tatattgata tctggccttc catcaccatc agtgtctata tttatatccg
   155221 gtattccatc cccatctaca tctacatttg tcacatctaa ctttaacttc ttttcatcct
   155281 cactaccttc aatgtaattt atatcatctc caatatattt tacagtaata gtttgttcag
   155341 tagtaaaaat atgatgattg ctatctaaag gtctccattc aatagatgca gtactataat
   155401 tatgactctc actaccctta ttatgagttt ttaattctac tggatcttta tattcctttc
   155461 cattaatata gaattgtacg taacctcttg gagaggcaca atctggtcct tctttcttat
   155521 ctggtgaaat agtaacattt aatgtaaacg tatctgttgg tttaaaaaca tcagttttag
   155581 ctttagactc ttctacaact aatgaagttt ctgtatcagc aggaataatt tctgccttat
   155641 aatatgctct atgcccccaa taagcttcat taaaaggata tacatttgaa aactgtgttg
   155701 atgtaatgct taattgatat tttccagcat caacttgctt tgtaaggtca tcacttccta
   155761 aatttgtatc tggttccatt gtttcctcat ttaaacgttg agaactaata gtcataaatt
   155821 ttttatctgt gagtttttca cctttaggag taattattgg aataccccca tcttttaata
   155881 tccaatctaa aaatgatttt tctacatctt cttcaaatgg taatccatca tatcttttaa
   155941 taatcaaata tggtggagta tcatcaatag taaattcttc atattgcttt aaaaattgag
   156001 aacctgaacc tatatcttta acataaaaat catctggttt tatatttcct ccagtaattt
   156061 tatctataac aactaaatta acagatactt cagatccctt aaattgttca gaaaaccata
   156121 agtaaagaac cccttgatca tctgtataac taggtgctcc ataaggataa atttttccat
   156181 caattagcat tttaaaatca tcaactaatg tagtactaac tttatcttgt cctaaatact
   156241 ttaaagatat tttattcata aaaacttttg ttttcttttc taaatcaccg tatgcaactg
   156301 ctccacctaa acttttgaat gttgttgctt ttaatgaacc acctgttact ataacatctc
   156361 ccgttgtagc acttaggtca aaaatccaat ctcccactcc tgtcatataa ggtaaaatcg
   156421 ttcctccagt tacaagtata cgatatcctc tatttgttcc tggattaaca catccatccc
   156481 caaatgcact accatgtgca cctccatatg aataggaaag tccaccatta attgtaatat
   156541 tcccactata accagaacct gtgctaggat ctactactga gggacttaat gcattctttg
   156601 ttgttgtata gtatcctcca cctattccag ctccatggta tgcaccttta gcagttatag
   156661 taccaccatt gattgtgata tctccaccac taccattacc gcctccacct attccagctc
   156721 catatcctgt attacgactc gattcttgac ctatagcagt tatagcacca ccattaataa
   156781 taatatttcc tccactttca gtatttccac cgccaatacc tgcagaataa taatttccaa
   156841 caacttttaa acttcctcta ttattactat ctagtagtgt aaggcgatct ccttttttta
   156901 acttgtctcc attttctaga gttacatctc taggaatttt tccaccctca ggaactataa
   156961 actcgccttc aatatctcta tttacaacag aatcatcaat aattagagta gtaccttttc
   157021 ctgctctcat acctggataa tatacatcac ctgactctag cttgttttca ctaccatctt
   157081 gtaatataac atgtgcatat gcaccaccat ctttatctgg tgttaaagta aatgggctat
   157141 tagatgcagt tttaatattt actccatcaa atattaattc agcttttaca tctttaggta
   157201 taacaatcct atgtgttgtt ggagtatttg gattattatt ttgaattgtc atttgttttc
   157261 cactaagaat agttaaaacg ccacttgcaa atttaaaatc gacatttatt tctccaccac
   157321 taattttaaa gtctcctaca gatgtaggat cttctgcagt ggcttcttcc acaactaatg
   157381 cattcatatc tccttctgca tttcctgcat tagaatcttc ttctgcattt cctgcattag
   157441 aatcttcttc tgcatttcct gcattagcat ctccttctgc atttcctgca ttagcatctt
   157501 cttctgcatt tcctgcatta gcatctcctc ctgcatttcc tgcattagca tctcctcctg
   157561 catttcctgc attagcatct ccttctggat ttcctgcatt agtatctcct cctgcatttc
   157621 ctgcattagc atcccctcct gcatttcctg cattagcatc cccttctgca tttcctgcat
   157681 tagcatcccc tcctgcattt cctgcattag tatctccttc tgcatttcct gcattagtac
   157741 tttcttctat agtatctgcg aaagtatttg acgcattaaa tgatgctact gatccaagtc
   157801 ccattgagat acttaaaatc attgatagtg ctttcttttt acatttttgt tgcataaatt
   157861 ccccctcccc ttaacaattt ttaatataca ctgtatacat ccttatatac actctaataa
   157921 ttcttaatat acactgtata catccttata tacactctaa taatttttaa tatatactta
   157981 aaacttatat ttgtcaatga atatacagtt tttttcaacc ttatatatta taagtattca
   158041 ttatttgcta aataactaca ataaaaattt taattatata aaatttattt aatcttttat
   158101 ataataatac aaggggtaat taattgaaaa aactagtaaa aatattaata aatattattt
   158161 gcattattac gctaactttc tctagccttt cgatttacat aaaattatct gaatataaaa
   158221 agctgatgaa gtatatacgg aactcagaga aaacactatc aataatagca aacatcaaga
   158281 actttatgat aaaaataatg attatagatt ctggcttaaa ataaacaacg taaatataga
   158341 ctatcctgta gtacaaggat ataacaatga tttctaccta actcatgatt tttataaaaa
   158401 ttatcttcct ttaggtagta ttttcatgga ttatagaaat aattttgaaa atgataagag
   158461 tttaatagtc tatggtcatt atatgaaaaa taaaactatg tttggtcagc tagaaaacta
   158521 tactgatgaa gtatttttca aagaaaataa tttagtagaa ataaattata aagtacaaac
   158581 ttatacttat gaaatttttt cagtatatac tgctgactta attaacagag attatttaag
   158641 tatacacttt aataataatg atgagtttaa atattctttg aattatataa cctaaaaatc
   158701 agtacacaaa tctgatataa aggtagatat ttcagataaa attataactt tgtatacttg
   158761 taaatatgaa tttaaagatg ctcttactat agttcatgct aaattaattt caaaaaagag
   158821 acctataagt aggtttgtgt aaatgcagac ttatctacag tcttttttga acgtaaaatt
   158881 ggtaagtata gaataatatt catattaaac ttttgtaggc aaagaaatga aaaatcaaag
   158941 agaaataatt attacagatt tagattacca agctgaatta agaaagtgta aaactatgga
   159001 ggatgtagtt ggtgaagata gtatataata gtttaactta taaattatct tggtgatatt
   159061 aatgaagttt caaagtatat attatttatt gatataaata aaattaaatc tgttgctaat
   159121 agatgtacct ttgtttggag acaaactatt gaagaaatat aactaaaatg ttgaagtagc
   159181 tacctgactt tattttgaaa tgcgaacaag attttggcat taagataatt tagaaagaat
   159241 cactggtaca caaggatgtg aacttagaat gaatagaagt attcaggcat aaggagcttt
   159301 cacccaaata aaacatagta tgaactttaa aagaattcta atcagagaca atcaaaatgt
   159361 tctttcatag tttatacctg tagtgttaga catagtattt ctaagtttca caaataagat
   159421 aatcattaat aaatgtagta tgtatattca tcctctcaaa aatatttttt aatcttacac
   159481 tttgtaaatt attctatttt aaaatggtat ttttatacct ttatttctta tgaccgtttt
   159541 caagctcaaa ttttgcataa atataaatta atgaaaagca agtaaaaaaa gaactgtcgc
   159601 acagcaattt aaaattactc attcgacagt ccttttttcg tggattaatg gtggagaaga
   159661 atcacaagaa taatacccac gattaaacct ttatacaata cattttatat gactttacca
   159721 tcactaatag ttattataca atcagccatc ttagctattt catcattatg agttatcata
   159781 accaacgtct gcttgtattc atttacacaa tactttagta aattcatcac ctcattagtt
   159841 gttttactgt ctaaatttcc agtaggttca tctgcaaaaa ttattgatgg cttattggca
   159901 agtgatcttg ctattgcaac tctttgttgt tgaccacctg ataattcatt aggaaattta
   159961 ttaatctgac tttctaatcc taacttagtt attaaatcat taatataatt attatctatc
   160021 tttcctttag caattaaaat aggaagaact atattatcat aaacattgat aacaggtatt
   160081 agattatagt tttggaatat aaacccaaat tctttacttc taagattaga tagcttttca
   160141 tcacttaaag tatataaatc taaattatcc ataaatacat tacctaaagt tggtttatca
   160201 agccctgcca tacagtgaag taatgtgctt tttccagaac cactttgtcc aattattgca
   160261 ctaaatttat ggggttctat ctctaaagta attccatcaa cagcctttat ttcattttct
   160321 ccttttccat atattttttt aatatctata acttttaaca tcttcataca tttacctccc
   160381 aaattattca ttctctttta taccttcaat aatattcata ctttcaaaat ctctattact
   160441 tacaactact gctattaaac atacaaatac agatatagca aagaatagta aagattcctt
   160501 aattgggaat gtaaaagaca taaaattctc tattccatag tttatatacg catcattatt
   160561 ccaatttgta aatttaacta gatttataaa tgatggaatc atagctatta taaagctaaa
   160621 aactgcatat gctaatgctt catatataag catttttttc atatttttaa gactaacacc
   160681 taatgctcta agcgttgaaa tttctttttt tctaattagt agatttgttc ttatagtaca
   160741 gaaaatatta attgatgcta ttattaaaac tagtgcaatt attgctattt gtgatttaat
   160801 gtaactttta tatatacttt ctgacatttc atgataactt aatctactat taaatagaga
   160861 ccctggtata cttcttgaaa ttttctgtat ctcattatta acaatctcat catatggatt
   160921 ttctaaattt atgcctaatt gagtgtattt ttgttctcct gttatgtttt tagagtgaat
   160981 attacttgtt ataatttcta gatctggcat aaaatcgcca tctcccatag caatccattc
   161041 atcctttaaa attacagcca ctcttacctt catctcttta taaacaattg tattattttc
   161101 ttcaacagga atttttacag ttattatgtc tcctatattt aattctttga atataggctt
   161161 tatagtatga tcatcaacta tatcataaaa ataattatat actgctacat ttggatatcc
   161221 atcagtgtcc tttttaatat catctaagct accttcttca acaaagtcat ttaacttttc
   161281 atctatataa tcatcatcat aaagctttaa aactaattta tcttccatta tctctttttt
   161341 tctactccat tataggttgt aaattctttg tttatatcct tattattaaa agtaaacatt
   161401 ccatttgtta tttgaatttt atgtatactt ttaacaccct taattttttc tatattctct
   161461 acatcactat ccgtgtattt tgatatttgc gggtctgcat ttactccaaa ttgcattgtt
   161521 atattatatc tattttgcat atcttcaatt ttactgttga cctcttcttg catacttgag
   161581 aatgtagtaa tgaatatata tcctcctaaa gcaatagaca acatagatat agcagctcta
   161641 accttatttc ttccgatatt tttaagtccc ataaatccat aaaatccaaa tattttgctt
   161701 actagtctgt ctattccaag tctacttctg tgatttttaa ttttgtctgt atttattatt
   161761 gattcaatag gtgatatctt gccgatttta aaagttggta taatacaaga tataaaaaca
   161821 gaaatcattc caaccaatat agcttttata actatttcat tatttatata taatttaggg
   161881 ttaagaccag cttcactgta taaaacttcg ttataattac taattcctat atatgaatat
   161941 gtaaccccag ctactaaccc aagtagtata cctattattg ttataattaa tgcttgatag
   162001 attatcatac accttacgtt tcttttcttt gcgcccatca gtctaagcag tcccatttct
   162061 tttaccgatt gatttagtgt aatattgaaa atattaaata tgaaaattat agatactgta
   162121 gttattaaaa catttctttt aaaaacattc ggatcattct tatcatcttc tacataacga
   162181 agttccctta caagaggtac atttggtaga aagctttttt gtcctaactt atattttttc
   162241 ataagataat cacattcacc ttcaatattt ctccatccac ttttaaaact taatatacta
   162301 ttataactaa tcgcatcatt aggtataatg ttgtttgttt catcattgcc ataagttact
   162361 gcttcgtatt gcaaaaccac atcatagtac ccttttggtt tttccataac tcctactatt
   162421 ttaaattctt tatttataga aaataatcga ttacttccgt tagtatcttt atagttcttt
   162481 tttattgtta aatttaatgt agatcctact ccttcactta aattcattgc ttctagtgct
   162541 tttttctcta atactatttc attgttgttt ttaggtagtc taccttctat tattttgttg
   162601 tatctacttt ttagatactc ttcgtttgat gaagttaata taaatgagtt tcctttttta
   162661 tctgaaatac gtcctagatt ttgtaccaaa ttaccctttg atactttttc atcagtttct
   162721 aattttttag catcatcaag tgtcaaatca ctaaactcta catggtatcc actgtaaagt
   162781 tcatgtattg ctactacatt gttttcattt tgtgaatctt ttataacact aggtccaaat
   162841 atcaacataa cgcctaacat aactcctatt attaaaagta gtgttctaag tttatttttc
   162901 tttaaatatg ctagtgatat ttttaagtaa atccccatat aatcctccta ttttactata
   162961 aattatttat ccaactcatc tgttaagtag attggtggat attttaaatc ttttaattct
   163021 tcattatttt ttgaagctta ctaccatctt cctcatgata aacttgcagt atcaccttat
   163081 ttacatgtag tgcataataa tcaccattat aaaaatatta gtatttataa cctggatagt
   163141 ttttgtaaaa tgatttataa agtatcccat cctaattctc ttttgtatac ttttcttttg
   163201 taatacgctc tatatcatca cctgaaactc cttgatatgt catatattta tctatatatt
   163261 tttcagcttc attccatttt ctaaaatagt tgttgtatat aataaatcct attatggcta
   163321 taatgcttat aattaaagtt aataaaatag ctttgtattt tctcatagtg aatcttccta
   163381 cttcaattta aattctttaa taagttttaa ttctaaagac ttagttttat catcaaattt
   163441 cttaacttga atttttatat ctcccaaatt atcaacctct acatttcctt cacctttatc
   163501 aaatacttct tcaatttttc taaaaaattc tttctcactt atttctacat gaatcaatga
   163561 tctatatgtt ataaatggcc attatgaatt tatcaccttc tgacagcttt tcattataag
   163621 aaaaatcttt aacacattga attgataata tttccttcgt acccttcttg tccttagtca
   163681 ttgaataatg taaaacttgg ctagattgtt cttttgtata ctccaagttt tccaaagaca
   163741 aaacaaaact tccatctgat ttattttcag ctaccctaag accactattt tctattgatt
   163801 ctgatatttt ctttgacaag tcttcttgat actagaaatc tgttcaatgg tatatatttt
   163861 ttcatttgta tctgaaacct tatttgtgca tcctgttatt aaacctagcg ttaagcttat
   163921 agctataacc atagttattg taattttttt tatcttcata taatccactt tatatattga
   163981 aaactcgtta tttatcataa aaaaaaagac gctatctttt tctattaaaa gataacatcc
   164041 ctatatgttt agtatcaata tatgttcccc aactggtagg ttaatcgacc caactatcag
   164101 tattttgatt taatggtata taaatattca atataaattt gtctttttta tcttcaaatg
   164161 ataaatctcc tctatatttt tttatagaag atttgatgct ttaaatccct attccatgta
   164221 caagtttatc ttttttatct gttaataata aacttttatt ctttctaatt gaatttattt
   164281 tactattctc acatttaatt acgaaatagg actttgagat agttcctttt atttgtatat
   164341 atttatcaat acttttatca tgtatcttat cgcaagcttc tattgcatta tctaagtatt
   164401 tgcaaatata ttagatacat ctatttgttt tataaaattc actttggaaa aattgatatc
   164461 acaaatgaat ttaatttttc ttttttcact tacatcactt tttttattta ttattatatc
   164521 caatataaca ttacctgtat tgtaaattga tttaaattct ttaatttaat cttttaaact
   164581 atttacatac ccatcaattt tcctttttta tatttgagat tttctacaca atatatatga
   164641 ttatttatat catgataaag cttcttaact ttagcgtgtg attcttgaat acttagataa
   164701 tgagaatact gcatatctag cttatttttt attacttcat tttgcgattt taacttattt
   164761 tccttaatta tttttataaa cactataata atgactaagc tactagctag tattaaccta
   164821 ggtatcacaa tatacccaac tatatatatt tcctaatacc caccaaatcg atacattttt
   164881 ctatttatat aaattattaa tatagtaaat aaatttgtta ttaaagcaac agataagtat
   164941 atatagttta ttttattatc tttatctagt cccaatcttt tattaataaa tttaaatata
   165001 gcacaagcta ctatataact attattataa gataatagta tatatctact ttagcattat
   165061 cataactaaa cactaataga gcttcctctg atgatattac attacttgta actacaaaaa
   165121 ataaatttat agatataaca tcttttatta aagggtgata tacgtcaaat aagaaaaatg
   165181 aaactatata tttaacaatt cctatcttat aaaaataatt atagtaagtt ctcaaataat
   165241 aaatatcaaa taatagatta tatcatatag atttttcttc atattataat tatgggtctt
   165301 atcaacgtta aataatataa tgattttagt tataagataa gctaataata cagtaaaaaa
   165361 agatattttc ttagtcttat ctgtatcttt atcgtaagtt aatatacttt ttagtatcat
   165421 tattggtgta aacaatgata atattaataa tattttattt atatggttta acatattcta
   165481 tcaccaataa attttagaaa cccctctttt atatctttat atctatatct actaataggt
   165541 acttcttctt gaatgtctaa tattgcagta tttgacttta tattttctac atagtttaag
   165601 ttaattatat aacttttatg acatcttaca agttcctcta tatttaaatc tttttctatt
   165661 ttttctagta tacatatagc atcaaaagtt ttattttttg tatgtattag catgttcttt
   165721 ttttgaactt ctatctattt ttttgctaga gtagattttg tatgtgttag acttattttt
   165781 atttttttca atttttttga gacatgttaa tatgtgtttt tctagttctt gaaaatttat
   165841 tggctttaat aagtatcaat aagctcttac ttcatatctt tcctgtacat aatttttaga
   165901 gatgttataa atattattat ctacttttct tatgtttctt gcgatatcta tactatttag
   165961 ttctgccatt tttatatcta agagtagtgt atcctctcaa ttaactttgt aatggttctt
   166021 cttttgagct atattttttt aattcgatat tctttgtttt tattttttaa tatattatca
   166081 acttgatttt ttattacgat ttgtatttct ttttcatcat cacaagctgt tattgtaatg
   166141 atgacctctc ctaatatttt atttttattt agattcttca ctttaggtta aaacttttta
   166201 aatgtattta tcaataatat ttaaactaaa aatgtataaa aatacctata tccaattgga
   166261 tatagatatt cgtggatttc aatgttggag atgaggggag tctataagtg gttatttgat
   166321 tgttttgttg gttttgtaaa agttgataat acagcagttt acatataata ctatataaaa
   166381 tttttataat ttttttgtta tttgttttta taattggggt atagttgggg tataattata
   166441 taaagttatt acacactata atattaaact attttacacc ttttgatagt gatattacat
   166501 agtcattatg tatttacctg taaaaaatat tttattgtta tcaattggac atatgttatt
   166561 ctcatcttct agtactttca tagtttcttt atacatcaat tttaccttta taaaaacttc
   166621 ttctgttaag aaacaatttt aagttcaaac agaatcaaac atatcataaa gcttgataat
   166681 gctaaattac aaacaatcaa tataagaaat attcacttat aaaattatca tttttacttt
   166741 aattaataat taaaccataa aagtatatta ataatatcat gctaattttt tgtatctctt
   166801 ataagttttt caagtccatt aaaattaatt atctttattc tattattatt taacttagag
   166861 tttatggcca tattatatgt tttaaatact ataattggct gaatctcttc aatttcacaa
   166921 ccaaatttaa tttcaagatt ttgtttattc tctaatacag atttatattt tttctccatt
   166981 ttacttataa atgaatatgt tttgtttata tcacatttaa atccatatgg tgtaaattta
   167041 taatatatgt ccttacattc tataataaat aatttttttg taactactgc aattaagtca
   167101 atctcattag ataatgttat aatcttttca ttgttaatat aaactttatg agcatttatt
   167161 ataattttat ttgtatattt cttcaatata ttgctacaat ctataactag attatttttt
   167221 atttctcttt ctataatttt tgagttaatc ttcttgcatt ttggaagaag attataaacc
   167281 aactttctta ttaaaatttc ataggaatgt a
//
LOCUS       DAEQAF010000002       117946 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.002, whole genome shotgun sequence.
ACCESSION   DAEQAF010000002 DAEQAF010000000
VERSION     DAEQAF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 117946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 117946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..117946
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.002"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            378..1706
                     /locus_tag="KRN00_000133"
     CDS             378..1706
                     /locus_tag="KRN00_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1826030.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            2459..3292
                     /locus_tag="KRN00_000134"
     CDS             2459..3292
                     /locus_tag="KRN00_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH1826031.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDQMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            3385..4317
                     /locus_tag="KRN00_000135"
     CDS             3385..4317
                     /locus_tag="KRN00_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1826032.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            4369..4851
                     /locus_tag="KRN00_000136"
     CDS             4369..4851
                     /locus_tag="KRN00_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1826033.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQEAMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            4863..5732
                     /locus_tag="KRN00_000137"
     CDS             4863..5732
                     /locus_tag="KRN00_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1826034.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIGAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            5775..6530
                     /locus_tag="KRN00_000138"
     CDS             5775..6530
                     /locus_tag="KRN00_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1826035.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSSNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNEFLQDGKKIYSEFQNKMK
                     KENNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVDKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGVVEFVIPNKVIKRLR"
     gene            6572..7393
                     /locus_tag="KRN00_000139"
     CDS             6572..7393
                     /locus_tag="KRN00_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBH1826036.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            7398..8159
                     /locus_tag="KRN00_000140"
     CDS             7398..8159
                     /locus_tag="KRN00_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBH1826037.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKIDPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKYKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIFVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    8320..8577
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8690..8929
                     /locus_tag="KRN00_000141"
     CDS             8690..8929
                     /locus_tag="KRN00_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1826038.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            9233..10228
                     /gene="ilvC"
                     /locus_tag="KRN00_000142"
     CDS             9233..10228
                     /gene="ilvC"
                     /locus_tag="KRN00_000142"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBH1826039.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDYT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            10281..11969
                     /gene="ilvB"
                     /locus_tag="KRN00_000143"
     CDS             10281..11969
                     /gene="ilvB"
                     /locus_tag="KRN00_000143"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBH1826040.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKTFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWSAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            complement(12330..13460)
                     /locus_tag="KRN00_000144"
     CDS             complement(12330..13460)
                     /locus_tag="KRN00_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1826041.1"
                     /translation="MKGGVRKRSNKWYYYFDLGIVEGKRKKVERVGGNTKKEAEKALR
                     EALNEYENSGIVFEESNISLSDYLDFWYKEYVLLNCKYNTQESYRINIEKHIKPKLGA
                     YKVKALTPAILQNFINKKYKEDYSQNTLQVLKAILHRSLKSAVHPYKHIRENPMQYVS
                     IPKTKSKTETNKIKTITLEEFNQILNIFPQDSFQRIVLLIGFHTGMRRGEIIALKWDN
                     IDLDNKTITVKHTLIKKPNGMFELGQPKTESSCRTIFTGDTLIKALKEHKLYQKKMKL
                     KYGEFYFDSDWVCTKENGQQVNTHTLDTIVRQIRVALNNDFHFHSLRHAHATLLLENG
                     ANIKDIQNRLGHSQLSTTMDTYSHVTDKMKNETVDIFEKITN"
     gene            complement(13700..14206)
                     /locus_tag="KRN00_000145"
     CDS             complement(13700..14206)
                     /locus_tag="KRN00_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBH1826042.1"
                     /translation="MNKLDALLDLANNEEIEIYYTDKIADDIKGLYINRQGLKIISLL
                     NSLKQNNAKLIEILAEELGHHFTSVGNYVSSKNSYKNKILIDKTENKALKWACEFLIT
                     EEEIIHVINSHATSVYEIAEELQVSINFLLKRLEFLSKKKSMLDLGNNRFLVLTNLPN
                     FYIYEDIF"
     gene            complement(14469..16058)
                     /locus_tag="KRN00_000146"
     CDS             complement(14469..16058)
                     /locus_tag="KRN00_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH1826043.1"
                     /translation="MKSIISDVINRFNATPFLFVGSGLTRRYYNLPNWEDLLKVFAEK
                     ISNDDFIYTSYKNKAKSENPKMGINPRIAELIENDFNKKWFSDSSIRSLDSKYLDIVK
                     SGVSPFKAEIAMYIKNNSKIVDKYQDEVEKLSNISKKSLSGFITTNYDCFLETIVDNY
                     TTYIGQENLVFSSIQGIAEIYKIHGCVSSPNSIVINEADYIDFDSKSAYLAAKLMTIF
                     VEFPIIFIGYSVTDVNIKKILNAIVNCLSNENAKKLEERFIFIEYEKNFNDIEISSHT
                     IAFDNKMITMTKIKLEDFNLLYEALSEKKSKLPVRILRMFKQEFYDFTITNKPTAKIR
                     VGSVDDTRIKDEDLVLAVGKASDFGLKGLKGLSFDEWYRDIVMNDLEFSSDELLEYAY
                     PSLIKQYNKLPLNKHLFNSTLEFPDYRTIALESDFENIISNSIKKNRNNTYIKNRSVY
                     GIWNDEHQSFEKATRLIAFLEEKEIDTEQLENLLKKIFEENPNILESAKTSEKTNLRR
                     LIRIYDYMKYSNMQKSLGYSE"
     gene            complement(16082..16645)
                     /locus_tag="KRN00_000147"
     CDS             complement(16082..16645)
                     /locus_tag="KRN00_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1826044.1"
                     /translation="MSILSDRLKFLRKEKGVMQKEIANYLNITTSAYGFYEQGKRTPT
                     PEMLSSLAEYFGTTVDYLIGRYDNKASNISSKTSCNNTLFQKRLKELRAEKNMTQEDV
                     ANKLNLTKSAYGYYEQGKTVPDAYMLSSLAEIFNVTTDYLLGRSIVKNDIDTVAAHRV
                     NPHKDLPEEAQEQLNDYIEFLINKYKK"
     gene            16798..17019
                     /locus_tag="KRN00_000148"
     CDS             16798..17019
                     /locus_tag="KRN00_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826045.1"
                     /translation="MNNLKELRTERNLKQKDVALKVGITTSYYGMIESGTRVPSLAIA
                     IKLSKCFGVSIEKIFLNTNTTRCCLKERS"
     gene            17022..17838
                     /locus_tag="KRN00_000149"
                     /pseudo
     CDS             17022..17838
                     /locus_tag="KRN00_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902586.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein/antirepressor Ant"
     gene            complement(18017..18196)
                     /locus_tag="KRN00_000150"
     CDS             complement(18017..18196)
                     /locus_tag="KRN00_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBH1826046.1"
                     /translation="MSTSLPKYTLRINRVLLEKIKYIAESEGRSANKEIEQIIKKHIE
                     DYEQRKGEIKINIEE"
     gene            18273..18410
                     /locus_tag="KRN00_000151"
     CDS             18273..18410
                     /locus_tag="KRN00_000151"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826047.1"
                     /translation="MKHEQTTLRIPEDLYKALIDLSSEIGMPIASIIIIACWLYISKI
                     N"
     gene            18421..18645
                     /locus_tag="KRN00_000152"
     CDS             18421..18645
                     /locus_tag="KRN00_000152"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826048.1"
                     /translation="MQNECTALFIRELTDKLFSLAVFSSNSFRTLGILRVERTLSSLL
                     YEIDLSSLTFEFLIMSLIAYRISEDLRIPV"
     gene            18829..18999
                     /locus_tag="KRN00_000153"
     CDS             18829..18999
                     /locus_tag="KRN00_000153"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826049.1"
                     /translation="MEKVRMTVRLVPKLNQDVQKIAKKCGKSKNSIIIDACWDFVEKI
                     KKENKFNIESEE"
     gene            19002..19805
                     /locus_tag="KRN00_000154"
     CDS             19002..19805
                     /locus_tag="KRN00_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBH1826050.1"
                     /translation="MNNLTIIKQNNKYLVESREVAELIEKDHNQLLRSIRGYISVLEQ
                     SAKLHTDDFFIESTYKNENNQKYPCYLLTKKGCDMVANKMTGEKGIIFTAIYVAKFEE
                     MEQVLKNGPQPKLPTTYKEALQHLIEQVEVNEKLQLESKMKEKVIKELKPKADYTDMI
                     LKNKGLVTITQIAKDYGMSGKEMNKILHERGIQYKQSGQWLLYKQHQGKGYTHSETID
                     ITRSNGMPDVKMTTKWTQKGRLFLYDLLKTNNILPDIEKEYSYQTSILG"
     gene            19852..20061
                     /locus_tag="KRN00_000155"
     CDS             19852..20061
                     /locus_tag="KRN00_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826051.1"
                     /translation="MENKKIEEIEKRITMLENQLQAQLFSQITAQSNSDFIDYMYQCI
                     VLYLHEMNKSEKRKISEITKERIRK"
     gene            complement(20071..20445)
                     /locus_tag="KRN00_000156"
     CDS             complement(20071..20445)
                     /locus_tag="KRN00_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826052.1"
                     /translation="MQFSNNISKELQESIRKTVSDTSNTEYFYYAEFQYKIILKSIEE
                     FEKELDDEHEIALKLTNFGKDVLMIVEEVGYHNPCLIHYYGIVNGVYSEILQHTSQIN
                     FMITSVKKTDPSKPARRIGFIL"
     gene            20521..20718
                     /locus_tag="KRN00_000157"
                     /pseudo
     CDS             20521..20718
                     /locus_tag="KRN00_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            20749..21141
                     /locus_tag="KRN00_000158"
     CDS             20749..21141
                     /locus_tag="KRN00_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1826053.1"
                     /translation="MDISESITKQFSDSLKSLIEIEISKQETDRVKSQTIEQKVKVLE
                     PKDIVVLIKRGYPNYLITVEEARGILKLDTAFMRRLVSTGLIKSLVRGDGRKISRYEV
                     DDFIERNQGKNLDELLKAVERGDEIAES"
     gene            21122..21271
                     /locus_tag="KRN00_000159"
     CDS             21122..21271
                     /locus_tag="KRN00_000159"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826054.1"
                     /translation="MKLLSLDTNNKNVVTLKKDGKVIADIVFKDIKTGKKISVGILNK
                     KVLVK"
     gene            21342..21779
                     /locus_tag="KRN00_000160"
     CDS             21342..21779
                     /locus_tag="KRN00_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826055.1"
                     /translation="MVEVNVNVKVKVEAPEFTNALLVVANALGGLNLGKAMQIEPINI
                     TDMKEEKKVEVKKAEKIKKVEVKEDVKEEIAEAKEEIEKNNENTTSEVKYTKEEVRTK
                     AAQVSKSGKKDKLKELFGEFGASKLSEVKEEDYSAFMNKLESL"
     gene            21791..22957
                     /locus_tag="KRN00_000161"
     CDS             21791..22957
                     /locus_tag="KRN00_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HBH1826056.1"
                     /translation="MPLQHARLSASGAHRWLHCTPSIKLEENYPPSTSIYAEEGTVAH
                     ELAEVKLMLEYEKISKKAYNARIKKIQKSEYYNSEMEDYIQSYVENVVELVNDSKAIC
                     DDVIVMLEERLDFSEWVPEGFGTGDVVVISDGILQVIDLKYGKGLEVSAIENPQLRLY
                     GLGAYNQFEMLYDIDLIKTTIIQPRLDNISSEEIEVTKLLTWADNVKKKAQMAFNGEG
                     EFVSGSHCGFCRAKNDCRKRAEDNLKLARKYDFADTFALNKYEIADILGFAKNIQDWL
                     KDVQSYALEQAEKHGVKYPGYKLVEGRSNRKYIDEQEVAKVLLNSDYDEEKIYKPRTL
                     KGISDMEKAIGKKSFAKLLSDLIIKPVGKATLVVESDKRSEINSIDSAKKDFEI"
     gene            22972..23307
                     /locus_tag="KRN00_000162"
     CDS             22972..23307
                     /locus_tag="KRN00_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826057.1"
                     /translation="MPLDAGIKDKLDESISIILDLKDRKKSIEKDLDYEKDNLLDMLK
                     RLNITEYNSTEENAKVTVMDFKRESLIKDKVMSTFLEVNDNHLDRVYIPEHIKVSPVC
                     FVSVRAKDN"
     gene            23360..23932
                     /locus_tag="KRN00_000163"
     CDS             23360..23932
                     /locus_tag="KRN00_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma-70"
                     /protein_id="HBH1826058.1"
                     /translation="MSNQEITKLVENNLNLVHFSINRFFKSYVEQHPYLYEEFYQEGC
                     IGLYKAALNYDSNRGKFSTVAVSYIRIEMFKALRYGEKHYRNSIEGLDVSVFEDSKRP
                     LKDIHGFYEIQFNYDVDYIRKIARKSYLKDIDKIVDWILQDKKISDIGELLNVSSTVI
                     CGRIKLFSKQVRDLDKFGEITSNIKSIYQI"
     gene            23955..24527
                     /locus_tag="KRN00_000164"
     CDS             23955..24527
                     /locus_tag="KRN00_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HBH1826059.1"
                     /translation="MSNSVQSTKVVTGKVRLSYCNIFKSRAMVEGAEPKYSVCILIPK
                     SDKVTLGRIKKAIDAAKEQGKTSKWGGKLPGNLKTPIRDGDAERADEAEEYVGMYFLN
                     ANSTQKPGIVDKDLNEILDNTEVYSGCYGRVSINFFPYNSAGNKGIGCGLQNVQKLAD
                     GEVLGGARASAEADFSDDFEYEDEEEDFLS"
     gene            24527..26485
                     /locus_tag="KRN00_000165"
     CDS             24527..26485
                     /locus_tag="KRN00_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HBH1826060.1"
                     /translation="MRTLSIDIETYSDLDIKKVGVYRYVDSANFEILLFAYAFDNEEV
                     KVIDLVNDEELPKEVIEALNDNKVIKSAFNANFERTAISKFLNINLKPNEWSCTMIKA
                     LTLGLPGSLDSVSKALKFNEDKQKMKEGKALIQYFCKPCKATKVNKGRTRNLPIHDME
                     KWNKFKEYCKQDVVVEREIRNKLSKYKTTEREIKLWYLDQRINDTGIKVDTELIENAI
                     ECDKRYTEKLTKEAIKITGLNNPNSPAQLKKWLSDKVSFEITSLTKESIPEILKQVDD
                     ENVVRTLELRKLMSKTSIKKYEAMKLAKGNDNRVRGLLQFYGANRTGRWAGRLVQVQN
                     LPQNHIEDLDLARNLLKEGDFDLIELLYDSVPDVLSQLIRTAFIPSEGHRFIVSDFSA
                     IEARVIAWLAGEKWRLDVFNSHGKIYEASASQMFKVPIESIKKGSELRQKGKLAELSN
                     GYGGSVGALISMGAIKMGLKEEELQPIVTAWRNANPNITKFWWDVDKAAKKAIKDRTI
                     VEIQHGIKFIYNPGVLFIELPSSRRLSYLRPKIEPHTTFSGDKITYEGMEQTSKQWKR
                     IDTYGPKLVENIVQATARDCLREAMFNVTDAGYSIVMHVHDELVIDVDKKGGSLEEVN
                     SIMGKEISWAKGLPLKADGYECDYYKKD"
     gene            26497..28914
                     /locus_tag="KRN00_000166"
     CDS             26497..28914
                     /locus_tag="KRN00_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826061.1"
                     /translation="MDIKASEIEHINVRHDGQLMLAIGKNKLETHWKNKSILWSELVN
                     RLSKTLRTQETYTEYRKMSKTEKDRVKDVGGFVGGSLKNGRRKAENIANRSIITLDID
                     YANKDIWEDITLLNDYACLMYSTHSHTENNPRYRLVIPLTRPVLPEEYQAISRMIADT
                     IGIDMFDDTTYQPHRLMYFPSTSIDGDYIFKFQDGEFLNPNEILDLYLDWTDVSYWPE
                     SSRERQKFNTQLKKQQDPIEKAGIIGAFCRSYSIKETIETFLNEVYIPGIDETRYTYS
                     EGSTSGGVVIYDDKFSYSHHGTDPASGILCNAFDLVRIHKFGELDEDAKPETPVNRLP
                     SFTRMSEFASSDTKVRKTIGRENLDKAKDDFGDIDFEDDEWLTRLDYDNKGSYKKTTN
                     NILMFIENDPYLKGKIAYNEFSNRAVVLGKLPWRNDDKLNDWNDSDDSGLRHHIETIY
                     NISSPSKVNDALIIAFENNTFHPIKDYLNSLKWDGIKRVDTLLIDYLGAEDNHYTRTI
                     IRKVLVAAVARVFNPGIKFDNMMVLSGPQGMGKSTFIKKLGGDWYSDSLTTVQGKEAY
                     EQLQGVWLLEMGEMMATKKADIEAVKHFLSKSEDIYRVAYGKRTSRFLRQCVVIGTTN
                     DKEFLRDKTGNRRFWPIDTGVKKINKSIFNGQLDNERNQIWAEAVELYKANEQLYLSD
                     EEKKEAERQQRTHSEENAKSGIIEEYLNKPITKNWYDLSISEKREYIHGSDFGDLKEG
                     TILREKTCVMEIWVELFNGEPKQLTPILSREINDILKGLDGWEPHSSHLRFGKVYGKQ
                     RAYIRTK"
     gene            29195..29506
                     /locus_tag="KRN00_000167"
     CDS             29195..29506
                     /locus_tag="KRN00_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HBH1826062.1"
                     /translation="MLESKIEKRLKKEIELLGGKAMKFISPGEAGVPDRIVLLPEGHV
                     IFVELKAPGKKPRKLQQYKMRELRELGFKVKCVSTLKEIDDFIKEVKGWNLNHIHTKN
                     T"
     gene            29470..30840
                     /locus_tag="KRN00_000168"
     CDS             29470..30840
                     /locus_tag="KRN00_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1826063.1"
                     /translation="MEFKPHPYQEYIIRKTIDNNNIGLLLDMGLGKTVCTLTAISELM
                     YDCFDISKVLVIAPLRVARDTWSSEVKKWEHLKHLKVSKVLGSKLDRVRALSTDSDIY
                     IINREMVPWIVDFYKRKWPFDMVVIDELSSFKSNKAQRFKSLKKVLPLTKRVVGLTGT
                     PTPNSLIDLWAQMYLLDRGERLGKTITGYKERYFEPGQKNYQTGAIYNWQPKDGAENA
                     IHNKIKDICISLKAEDYLNMPRKIDNKIEIHLDSKILKYYKELEKEKILELEKDIITA
                     SSAAVAANKLLQLANGAIYDNDKNVKELHREKLEALKEIIDISNGKPIIVFYNYKHDY
                     NRLMKEFKSLKPRTIENSKDIYDWNNGRIQLLLCHPASTGHGLNLQSGGSIIVWFGLT
                     WSLELYQQANARLYRQGQRETVIIHHLICKGTIDEQVMEALENKDKGQSALLEAVKAK
                     LKEYRE"
     gene            30864..31001
                     /locus_tag="KRN00_000169"
     CDS             30864..31001
                     /locus_tag="KRN00_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826064.1"
                     /translation="MELISPGKIVRCAWCGRRFYKLDKSKVKYCSRSCSKRARRSDLS
                     G"
     gene            30994..31473
                     /locus_tag="KRN00_000170"
     CDS             30994..31473
                     /locus_tag="KRN00_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 region 4 domain-containing protein"
                     /protein_id="HBH1826065.1"
                     /translation="MDKESIKEIVRELRKEEREDRKKGVLYNTRLLMKHYNDFKRHID
                     SAVSEAKDVDYLEDDLGKLDNEELYILSIKKSKARTIIMIAHIDSAMKTLKLRQERLH
                     SYEKYRALELYYCDEKTYEEIAEILNCGVVTSRRWINEMIKELGVYLFGIDGLKLTV"
     gene            31959..32195
                     /locus_tag="KRN00_000171"
     CDS             31959..32195
                     /locus_tag="KRN00_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826066.1"
                     /translation="MPNFGTTFVTEEAVYNMSFRSNKAEAKLFTKWVTKALKQIRIHG
                     YYIATEKDQEWLDIRTEGKKVRKDFTDEIQEFVY"
     gene            32498..33472
                     /locus_tag="KRN00_000172"
     CDS             32498..33472
                     /locus_tag="KRN00_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826067.1"
                     /translation="MSNFKKRYIDVYRIDIINKINGSVYSDEEILKEVIKTFFKDKEY
                     CKENKNGINITKDKKFWITEVKCSEDDLIIKVKLEYTKYNQNTNIINAHTKEVEGNKK
                     MDQGDSNKQHLFIKFMKENNIAVVLFERVFVGVPMIELSKNLHLYYEDMIENNKFDNN
                     MSKTSINITQIASKDFIEQILDLDGVSKITLNVDREKFGTDEDNLFSNLNNSRRHNDL
                     IYKPTFRTRYLPSEVKRCCEKYIKGEEFRNKKINRIIIEGEKNKRKLKLDTEGIKLCR
                     EIEVSLDIDNHIDSEDIFDKMNNLIDDLIENNSVFFNLMYQEVAMSEA"
     gene            33493..34002
                     /locus_tag="KRN00_000173"
     CDS             33493..34002
                     /locus_tag="KRN00_000173"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826068.1"
                     /translation="MYKKVLNILLNYYKAINSKEVVELVLTPVLICIISYMFFNSSIN
                     KEVVISLNKDVLTLSGLLVAFGVCIITLLFTTYNKSISEAKDIKTERKVNGFNISYFQ
                     FIQLKAYYTVIMEILVVVICFINTIMLTRYYSNIIFYVLIFFTVHIILSLTTLIISMF
                     HLSWKDRGD"
     gene            34073..34765
                     /locus_tag="KRN00_000174"
     CDS             34073..34765
                     /locus_tag="KRN00_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1826069.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISSKYDISLNTLKSWIKRYNWASE
                     KKKGAPINKRGAPFSNKNSVGHGAPKENKNAEKFGFFSKYLPEETRELIQEISIKDKF
                     DILWEQITIQYAAIIRAQKIMYVKGKEEMVKELKKYESTENGEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDEL
                     KISVDYGDRNDS"
     gene            34743..35996
                     /locus_tag="KRN00_000175"
     CDS             34743..35996
                     /locus_tag="KRN00_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBH1826070.1"
                     /translation="MVIEMIVRVNFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSATHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANVVL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSRGLEKTLFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            36002..37441
                     /locus_tag="KRN00_000176"
     CDS             36002..37441
                     /locus_tag="KRN00_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1826071.1"
                     /translation="MLNIYISETDLIKVQLKKESTFNLVKVIEHYILKHRPEKYKQGE
                     EYYYGNTDVNNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNA
                     DDDNLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDSKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFVERGNSFVQEFLYDEYG
                     KMTDIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNL
                     DEIQEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDE
                     LERLKKQEDTQKEYDDLIPNNQDGVIDET"
     gene            37431..38924
                     /locus_tag="KRN00_000177"
     CDS             37431..38924
                     /locus_tag="KRN00_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBH1826072.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSIKYYLELEKQYKLAMSNIERDI
                     LIWYNRFTENEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWTSDGLNFSERIWGKHRPALVNELHTKLTQSIIRGENPKKLV
                     NDFAKRFKVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLRTSNICRE
                     LDGKIFDMKDYQVGITAPPFHCRCRTTTAPWFEDEEGYRAARGEDGKTYYVPSSMKYN
                     EWYEKYVKNNSKQTGAKYTKGDIEWNIRREEEAELYYDNIRNRKDDISKISKNTNWSE
                     KSIGQIKNHIFYNTHIMRDGTRRMLDSDYSMSVAWQRLINGTYEDIDILLLKHEYLES
                     IFEKKYNISNLEAHRMTEKKHDWYKELIKQKGEFEEDDCLNELIRKE"
     gene            38890..39132
                     /locus_tag="KRN00_000178"
     CDS             38890..39132
                     /locus_tag="KRN00_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826073.1"
                     /translation="MIVLMNLLEKNNEYVIYSYGYEENKLDGRIKIYLDDFYNYEIIK
                     ESKDEHISKSATLKAISKLIKAAKNNDLKKEMSYQC"
     gene            39441..40004
                     /locus_tag="KRN00_000179"
     CDS             39441..40004
                     /locus_tag="KRN00_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBH1826074.1"
                     /translation="MDWLKELLEGIKIENNKIDVVSLQKSIEKKIKETTITKEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            40016..40915
                     /locus_tag="KRN00_000180"
     CDS             40016..40915
                     /locus_tag="KRN00_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009323118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBH1826075.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTANVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGV"
     gene            40915..41148
                     /locus_tag="KRN00_000181"
     CDS             40915..41148
                     /locus_tag="KRN00_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826076.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            41158..41559
                     /locus_tag="KRN00_000182"
     CDS             41158..41559
                     /locus_tag="KRN00_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826077.1"
                     /translation="MENNLIDEIEKRLESFGYILKDGDKWLIDFIREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDSLIAYLTTYGKNKILTFRCLRW"
     gene            41553..41915
                     /locus_tag="KRN00_000183"
     CDS             41553..41915
                     /locus_tag="KRN00_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826078.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKVAKLEQTIKLFISPDISVKAGSKLIITNQNNITKEYIRSGES
                     AIYPNHQEIVLELLEDKA"
     gene            41915..42340
                     /locus_tag="KRN00_000184"
     CDS             41915..42340
                     /locus_tag="KRN00_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBH1826079.1"
                     /translation="MGRGGSVNFKELKKLQRNLQRLEESQLDKFCRDCAKELAARLIG
                     KAIKRTPVDTGVLRQGWNGVAYARALPVIKAGDTYIIEIINPIKYASFIEYGHRTRNH
                     KGWVKGRYMMTISVQELRGQVDVIIEKKLINLLKKVFDA"
     gene            42333..42770
                     /locus_tag="KRN00_000185"
     CDS             42333..42770
                     /locus_tag="KRN00_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826080.1"
                     /translation="MLNNIIDGISVKLDKSFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SKVSYPSGRTLKKNSFDVHYFPKSNDKSFEINEVAEMLLEELEYIEIDGDLVRGTNMN
                     FEIVDNVLHFFVDYNYFTIKSNNTDKMDTVELFGGLKRGDKLE"
     gene            42763..42939
                     /locus_tag="KRN00_000186"
     CDS             42763..42939
                     /locus_tag="KRN00_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826081.1"
                     /translation="MSKTLSKEENYKFTKEQIVNSKRYVNRKDLLNAILKEDELYSFS
                     EVEDMINNFMKGVS"
     gene            42940..44250
                     /locus_tag="KRN00_000187"
     CDS             42940..44250
                     /locus_tag="KRN00_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBH1826082.1"
                     /translation="MALGGGTFVTQNKVLPGAYINFISAKRATSSLSDRGIVAIPLEL
                     DWGIDEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKINKGVKAS
                     CSIATAKYSGTRGNDLKVIVTTNIDDNTKFDVVTLLDNKKVDIQAAKVITDLQDNDYI
                     TWKKDATLEASAGLVFTGGTNGEAVTGAEYQTFLDKIESYSFNALGCLAITTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDIGLVESSLIYWVTGAIAGC
                     DINKSNTNKKYDGEFDIDVNYTQIQLEEALKTGKFIFHKVGDEVHMLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS"
     gene            44268..44738
                     /locus_tag="KRN00_000188"
     CDS             44268..44738
                     /locus_tag="KRN00_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH1826083.1"
                     /translation="MFQQIKARDTISASKAECYVTIEGKRYNFMQAINLEAKMEKNKS
                     EVPILGSTTKGNKSTGSKYTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SSAGRQTIILKDCNMDSGIIVKFDADGEYLDEDMDFTCEDWELVEKFNIINGME"
     gene            44809..45249
                     /locus_tag="KRN00_000189"
     CDS             44809..45249
                     /locus_tag="KRN00_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1826084.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYIASDRFLDEEGKPVEWELKVLSSE
                     EDEVLRRNCTKRVKVIGNNGKPTGQFTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDITFEDKVEEAKN"
     gene            45592..45753
                     /locus_tag="KRN00_000190"
     CDS             45592..45753
                     /locus_tag="KRN00_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826085.1"
                     /translation="MDNFLIGVLASLTASLIGYIVCLCIKKVKSHSVQESDLDVELKF
                     SFKFKKNKH"
     repeat_region   46035..46654
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=46035..46063
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            46788..47312
                     /locus_tag="KRN00_000191"
     CDS             46788..47312
                     /locus_tag="KRN00_000191"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826086.1"
                     /translation="MWGKFKKLSLLKKILVIFLIYFVVFTVSMMIHQAIRDSKNRDEV
                     NEGNITKENIISEREKEDIYKQEMQAKVDFMIPEDLKDKTTYYVNILNPTKGEGYIVS
                     IQVENSRFNDENECRNFTKEFVNNIKDMNDIHSVRISFIVDVTLTYNVFLDDWNNIKN
                     NVNLIDDLDFSSGN"
     gene            47490..47678
                     /locus_tag="KRN00_000192"
     CDS             47490..47678
                     /locus_tag="KRN00_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826087.1"
                     /translation="MKIITDSSRADYFKQRRQNKKTFSVLLDREKVEKIEEHLKKQNK
                     TKTIWLEEKINEELEKEE"
     gene            47796..48617
                     /locus_tag="KRN00_000193"
     CDS             47796..48617
                     /locus_tag="KRN00_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBH1826088.1"
                     /translation="MKNELMMFEEKKVEVLEYNGQVLFNPYDCGRCLELSDSAIRNHL
                     SKMNDTQAVLLKNSNVLDKDFRKLHNTGEKFLTESGVYKLIFKSKKEEAERFQDWISD
                     EVLPAIRQTGAYITNNADPQALREKANEIESLDTVNKTIEILTPFLDGAGIDEKAKLL
                     TAKTIYKKAGIELPLEIEEKEHFFDTVQIATKLNIYSKSNKPAFHAIGEIIKKLDIQD
                     NEKLVVLESKRGWSGSVNKYSQSVIDKVRNWIEENNRPSKIAGEKKNYHVVYKIE"
     gene            48680..48853
                     /locus_tag="KRN00_000194"
     CDS             48680..48853
                     /locus_tag="KRN00_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826089.1"
                     /translation="MRESLLNEYNLKTDEDVEYFVKFANALYELKQNSEEKFQEYAEI
                     LRGILREQEERKN"
     gene            49671..50231
                     /locus_tag="KRN00_000195"
     CDS             49671..50231
                     /locus_tag="KRN00_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012424789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1826090.1"
                     /translation="MKKKVCFLFSILIVICLAIVGCSNSESPEESSKNNEPKKEEKKD
                     KEVVIGEKIISDKMEITINNIEFSYDVLPKVKESLYTHYPAESGKVYIDIAADIKNTQ
                     KQELNCSDLLTIEANYNDGYKYSSQTIVEDETTGFTYDNISSIDPLETKGVRFIIDCP
                     DEVKTSDKPVILSFTFDGNKYVYKMK"
     gene            50275..50844
                     /locus_tag="KRN00_000196"
     CDS             50275..50844
                     /locus_tag="KRN00_000196"
                     /inference="COORDINATES: protein motif:HMM:NF024637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HBH1826091.1"
                     /translation="MDDIVEYIFCSECGAKCLKGSKFCSECGTEIADIKMLNESIIKE
                     KEYDLKGIDLQHVMQETSFIKASSVRRLKELTGIELDDCRKILEEPYQKYYNENADML
                     EEKRKKEDDISKIRKAKEEKKEKEKIACCPACGSTSLTTHKKGFGIGKAITGATIAGG
                     IGLVAGNIGAKKVRVTCLNCGKQFWAGKK"
     gene            50965..51747
                     /locus_tag="KRN00_000197"
     CDS             50965..51747
                     /locus_tag="KRN00_000197"
                     /inference="COORDINATES: protein motif:HMM:NF021378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH1826092.1"
                     /translation="MGLFGGKEPCCICGGKGKNKVLENEYLCNNCFVDFTIFSSGRLK
                     TTSAMQVLADHEGIRKFINFSKKNRELLEKFVETNKINKFISIDENNKFIKISDIRKG
                     GDIIETVYATDEIIEFELLEDEESIVSGGLGRAVVGGALFGATGAVVGGVTGKKTTRK
                     IVNTFKIKITFNNINNPLEYINLINTRTKTNSSIYQNACNEAQEILSVLSIIVKNNDK
                     ANNEQDKTSSSIEQVKGLKELLDIGAITEEEFNTKKKELLNL"
     gene            51812..54163
                     /locus_tag="KRN00_000198"
     CDS             51812..54163
                     /locus_tag="KRN00_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBH1826093.1"
                     /translation="MATIQTSIRIFDGMTPAFRSMTASINTTINSLERLQGRLNNPLN
                     TGGIQTSHQSLNNIENILTRIEQNIGKADEQQRKFNEDINKGASNTDRLLGSVKKVVG
                     TYMGLKTIGGLANLSDQMTSTNARLNMINDGQLSDGGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGSAFSSTREIVSFAEQLNKKFVIAGASTEEMNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIKSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAASAETNAQFE
                     KMPLTIGQIFTSIKNNAVMIFGAIQKKIEDTVSSGGFRTFIVNVTDSLYVLGAVGYSV
                     FNGFIDLLSSPTFQGFANMMIVGISLITQGFGWLLTVLGSVINFISQGWSIIQPILIT
                     SIVLWGLYKTAVIAGALVTAIQVVWIALQTFWTNLLNGSLLTNIMMNIAAKISTDALS
                     GSMLLLITTIVMVVAAVALVIAAIFVAVAIFNHFAGTSISATGVVVGAFYFLGTCIYD
                     VFAGAWNIVMAFAEFFVNSFNIVIYNVQLLFYKFQNFVINAMGDVGGSFDNCATALAN
                     AFVSAANIAIKGINGVIKTLNLIPGVNIKTFGSLDKIDSFVKQYKDYQKTLKEPVKPA
                     EWKAPTMKLKNPVDSFKKGYEVGQNLENKIKDAFDISKIAEKAKKDLGLDDLWDDKYG
                     LGDRFGSAGLNSPLNDAAKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFT
                     GVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMIVSAEGIV"
     gene            54179..54868
                     /locus_tag="KRN00_000199"
     CDS             54179..54868
                     /locus_tag="KRN00_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBH1826094.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGAFSDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNIKVSLEEYAISEDADNGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKKVPKY
                     TIYKGQVLRLV"
     gene            54861..56753
                     /locus_tag="KRN00_000200"
     CDS             54861..56753
                     /locus_tag="KRN00_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1826095.1"
                     /translation="MSDDLVLANDRDIRLVIAHWEDFYEPAVIDGITWEIERRGSPSK
                     LEFTIAMDDILEFCEGNSVRIYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCLVPVFLNLGDIKLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKDEKKNGPAQSITKKNTGKKVPAIFTAYYPGNNAMEGGKTDCNGKPL
                     DVKSRTVAGPMNREGVKKTWYTDDFLKKHPVFEYGDKVKIILPGTAYDNKVYTVKDNG
                     GRIYVETNGTYHIDVLLANASECKKFGRKNGYIIIGGDEEQTYQVEGNNQSSTNNNSK
                     EDKLISIAKSKLGCNYVYGAEGPNNFDCSGFTQWCYKQIGIKIPRTASAQSKAGKAVD
                     LKDRSKWKAGDLLCRIGGGSSNHVVMYIGNNQIIHSPQTGDVVKIESVNSYRKGKAYT
                     HVRRFI"
     gene            56767..57027
                     /locus_tag="KRN00_000201"
     CDS             56767..57027
                     /locus_tag="KRN00_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBH1826096.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMRVVFGTIESISPLRVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            57032..57451
                     /locus_tag="KRN00_000202"
     CDS             57032..57451
                     /locus_tag="KRN00_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH1826097.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLHIEKSKIDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFENIKGKVQCRFSVHTKYGNIKAEKVVSV"
     gene            57452..58501
                     /locus_tag="KRN00_000203"
     CDS             57452..58501
                     /locus_tag="KRN00_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH1826098.1"
                     /translation="MFELMTFENIIKRMLDSVPNTLDKREGSIIYNALAPVAVELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLPATNTIAKGVFNIDIPLDSRFNLGE
                     YNYIAIERISEKTYKMKCETAGPIFELGKLIPIEYIDGLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHKVTVTGVVSTTINISAEITYKNGYTWEN
                     IKSIAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMINDVKSNL
                     TIDSNSIVVRGEVVG"
     gene            58494..59111
                     /locus_tag="KRN00_000204"
     CDS             58494..59111
                     /locus_tag="KRN00_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBH1826099.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNVENKEIKTLHEKLNDLSS
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDSI
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSSIKPCNMTLDYTRVLVSKDNY
                     MNFGITTLIGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            59123..60115
                     /locus_tag="KRN00_000205"
     CDS             59123..60115
                     /locus_tag="KRN00_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH1826100.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELTSNIETAKTELNTKIDQLIAGGSNVAYTQRVAIDDWVEDAESG
                     FKATVTHSLLTQRIVVNIIDATTKENIVPNFKIVDDNSIEIRSEVKVELNVYVINGNA
                     ETHFINATVDDNRVSEMTTYSSKKIEDRLVNIEEKVNGGLSNIATSVNELITYC"
     gene            60132..61844
                     /locus_tag="KRN00_000206"
     CDS             60132..61844
                     /locus_tag="KRN00_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826101.1"
                     /translation="MQTEWNFNYANYVQNVSLPPGRYKLECWGACGGAVDTSDWTDCA
                     KGGYSKGEIVFKKRTNLQICVGQSGYEKVSEGSSLTRSGFNGAGAAGKVTTGSFAYSK
                     YGGGATDIRLYHPSATWGNTESLLSRILVAGGGGGMKNNFASACSIGHGGGYVGVNGV
                     GRDRDFCGGGSQYQGGTSYDTEEYHGSLGKGGYGNIGIGGGGGWYGGAGSYSNECGGG
                     GSGYALNKDSYKVPGYIPTPEYYLENIVMTTGGNTTKADGYAKITLLQALPFLTVSSY
                     NSTQATFKADHTDPALLTKIEWFIDDVLKETITTNLTEEKTINYTLEDNALHTLKIVV
                     TDSNNATAEKVLSISKNIMPLPENVNLNDISTKLVEVNAGFKVGKTSIINTLALKNIE
                     ASLNNTLVELSEKIKTSFDSSDTSVQDLQNQVTQKNNTITQLETELSKRKRFITGTYT
                     FTKTDAENFNLSIYDKEGTSKTLTIPVNMGFSPSLIVLSGVTFSTTSKSYVYFDNVCN
                     SNFYNFGYNSDSTHSNPKAVGILNVSNVGYSSLVLTLYKLSMSEAVGIWAKEGATLTY
                     KIYI"
     gene            61865..62212
                     /locus_tag="KRN00_000207"
     CDS             61865..62212
                     /locus_tag="KRN00_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826102.1"
                     /translation="MNRNNRIIYDQTGNIWLQTGEATGDIQEWSKITELNFLDVEFGS
                     IDYSKQYIESINPVTKEPIIKDIEVILTDEQKRLQALEKELSMLKEENKNRDSEIVNT
                     AFEVENIKLNNNL"
     gene            62224..62394
                     /locus_tag="KRN00_000208"
     CDS             62224..62394
                     /locus_tag="KRN00_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826103.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKIDVFYAVNRITEEQYLELTSL
                     LNKEETPAEPIK"
     gene            62425..63018
                     /locus_tag="KRN00_000209"
     CDS             62425..63018
                     /locus_tag="KRN00_000209"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826104.1"
                     /translation="MTFKELVNKVRNLVLEAKNVTIEDTESKFTSENVEGALKECIDR
                     ADEAFQEADSGKTLLSTAIGSPATSEQTFQDYANYITGFKNTIVSKDNTINSLRNRYQ
                     STSGFFIYDKEHYPNGIVVGFKPDIVSYTTTNLVGEKYYCIYTPLFYFFYNARTKETC
                     FDSTDSHRGIDIKDNSWLPKGPVNGGAGYDYIAVKYR"
     gene            63077..63367
                     /locus_tag="KRN00_000210"
     CDS             63077..63367
                     /locus_tag="KRN00_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826105.1"
                     /translation="MEEISINLLCAVAGVVISYLAFRNSSNRKIQDDTETTTKLEQQI
                     TFLCENVRDIKHDVAKFNTSFLDISERVAKVEASTKQAHLRIDEIINRIGGK"
     gene            63371..63628
                     /locus_tag="KRN00_000211"
     CDS             63371..63628
                     /locus_tag="KRN00_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBH1826106.1"
                     /translation="MDNLISFIPEQLLILVAALYVIGAGCKKYKQLDNKYIPVVLLIL
                     GIGFSIWMLGLNPVAVLQGVICWGVAIGINQTYKQFKDGEK"
     gene            63889..64752
                     /locus_tag="KRN00_000212"
     CDS             63889..64752
                     /locus_tag="KRN00_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HBH1826107.1"
                     /translation="MVEVKEEKTFDEQIDILKSRGLIINDKEDAKFVLSNVNYYRFTA
                     YLLSFKNDDGSYKEGTTFEEVYDIYRFNKEFRILLTDLLGSIEIAFRTYIAYTLAIKH
                     GACGYLERESFKDEKFYINFLTALEREKSNNSDKLFIIHHKEKYEGKLPIWVATEIMT
                     FGMLSKLYSNMLPEDTRYIKNNLCRVNTLLVKSWLQSLTQVRNQCAHYGRIYNNNFRI
                     ITIKNEYKKYNLDNKKIFSYILAMKHLTMDKLIWNSFFIKLQKLINDYNNSIDLKLIG
                     FPNNWIEILAK"
     gene            64831..65643
                     /locus_tag="KRN00_000213"
     CDS             64831..65643
                     /locus_tag="KRN00_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1826108.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKFLAPVLADTFRKE
                     GHKADVIICPEKQFKTKAEEKTYKIPRVNSGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICNKLGTVFRNRRAKLDKGLYILNSSKPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKIPATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVIGGGACEKISSITKEHYKMIKGNDRFDTLYKALDFINR"
     gene            65800..68091
                     /locus_tag="KRN00_000214"
     CDS             65800..68091
                     /locus_tag="KRN00_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1826109.1"
                     /translation="MKNLSKKAVILSLSLVVVSPLVHKINAQDIEKNREVRYETRKAN
                     NLENMTMEEAFPDENFRKVICDKLSILDDGNPIGISQKAIIESTKGLTLGSKSIKNLS
                     GINYFIGLENFSCRGNNLMSLDLSSNINLKELYCNENQLTSLDLSNNRELTTLHCGEN
                     NLTDLVIENSKLDELNCRKNNLKSLDITKATNLTTLLCFENELTSLNLSKNQKLKILK
                     CDYNNLNDLDISTNLELQDLNCSFNQLENINLDNNKELVKLICHNNKLQNLNLKNHEK
                     LVKLYCNQEQLSTLNVENCINLEDLTCSRSNLKNLDISSNKNLKYLECVANKLTNLNI
                     ENNIELLELYCYDNEIKALDISKNIDLENLTCYKNKLDSLNTSKNKNLKYLYCSQNEL
                     TSLDVTKNTELVRLYCGENRLTSLDVSKNTKLKELDWSNQKKSTSTGGSSGSGGGSSS
                     TNEESSKPTSTPSKEKLTGADRNETSVKISQKGWNKADNIVLINDSSISDALSATLFA
                     KSKDAPILLTKNNNLNKLTEKEINRLEAKNVYIVGGLKSVDEKVVSDLKKKGLNVIRI
                     SGNDRYETSIKLAKELDKNSNLSKVVVVNGEKGLADAVSMGAISAKEEMPILLTNQND
                     DMKDIKDLIANKNISKSYVIGGESLFNNKEVNNTLPSVTKIAGSDRTETNSKVISHFY
                     SKDTLNDLYVAKNGMNKQDDLVDALSVGVLAGKTESPVVLVGNGLDDSQKELIKNKKF
                     KNITQIGGNGNEKAFNEVENLVK"
     gene            complement(68132..68317)
                     /locus_tag="KRN00_000215"
     CDS             complement(68132..68317)
                     /locus_tag="KRN00_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBH1826110.1"
                     /translation="MILLEQRKLRIGFNKSGKGSFTPRLILPMSWIKEMNISPDERDV
                     LVTFEDGKIIIEKTENE"
     gene            complement(68865..69041)
                     /locus_tag="KRN00_000216"
     CDS             complement(68865..69041)
                     /locus_tag="KRN00_000216"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826111.1"
                     /translation="MEQKESKIVYSKGGSGTYSAKISLPLSQLEKMGFTREKRKAVVI
                     FKEDEIIIKKSDEE"
     gene            69758..70435
                     /locus_tag="KRN00_000217"
     CDS             69758..70435
                     /locus_tag="KRN00_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1826112.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNSVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            70609..72645
                     /locus_tag="KRN00_000218"
     CDS             70609..72645
                     /locus_tag="KRN00_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBH1826113.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYRLKDDKISYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(72836..73402)
                     /locus_tag="KRN00_000219"
     CDS             complement(72836..73402)
                     /locus_tag="KRN00_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1826114.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRKRVNKND"
     gene            73690..74625
                     /locus_tag="KRN00_000220"
     CDS             73690..74625
                     /locus_tag="KRN00_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1826115.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            75098..76312
                     /locus_tag="KRN00_000221"
     CDS             75098..76312
                     /locus_tag="KRN00_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826116.1"
                     /translation="MQIKIGKVIQRLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLKQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHESLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(76661..77182)
                     /locus_tag="KRN00_000222"
     CDS             complement(76661..77182)
                     /locus_tag="KRN00_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1826117.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSSLQEEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            77538..78335
                     /locus_tag="KRN00_000223"
     CDS             77538..78335
                     /locus_tag="KRN00_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH1826118.1"
                     /translation="MEKREKRIIISSLLSVSILMGLVSIYSILNKEDIILTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            78445..79035
                     /locus_tag="KRN00_000224"
     CDS             78445..79035
                     /locus_tag="KRN00_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBH1826119.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEIVNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVRKDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            79101..80798
                     /locus_tag="KRN00_000225"
     CDS             79101..80798
                     /locus_tag="KRN00_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH1826120.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEVVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            81012..81851
                     /locus_tag="KRN00_000226"
     CDS             81012..81851
                     /locus_tag="KRN00_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBH1826121.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            82368..84224
                     /locus_tag="KRN00_000227"
     CDS             82368..84224
                     /locus_tag="KRN00_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH1826122.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    84307..84547
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    84613..84848
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            84933..86150
                     /locus_tag="KRN00_000228"
     CDS             84933..86150
                     /locus_tag="KRN00_000228"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH1826123.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            86267..86749
                     /gene="cdeM"
                     /locus_tag="KRN00_000229"
     CDS             86267..86749
                     /gene="cdeM"
                     /locus_tag="KRN00_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBH1826124.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            87014..88279
                     /gene="hisD"
                     /locus_tag="KRN00_000230"
     CDS             87014..88279
                     /gene="hisD"
                     /locus_tag="KRN00_000230"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBH1826125.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(88474..89226)
                     /locus_tag="KRN00_000231"
     CDS             complement(88474..89226)
                     /locus_tag="KRN00_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1826126.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCQGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIHIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(89344..89613)
                     /locus_tag="KRN00_000232"
     CDS             complement(89344..89613)
                     /locus_tag="KRN00_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826127.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            90088..91182
                     /locus_tag="KRN00_000233"
     CDS             90088..91182
                     /locus_tag="KRN00_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1826128.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            91184..92134
                     /locus_tag="KRN00_000234"
     CDS             91184..92134
                     /locus_tag="KRN00_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBH1826129.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFRANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     QGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQILM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVKHG"
     gene            92127..93311
                     /locus_tag="KRN00_000235"
     CDS             92127..93311
                     /locus_tag="KRN00_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826130.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DIYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            93324..94820
                     /locus_tag="KRN00_000236"
     CDS             93324..94820
                     /locus_tag="KRN00_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH1826131.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIIGRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            94843..95793
                     /locus_tag="KRN00_000237"
     CDS             94843..95793
                     /locus_tag="KRN00_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826132.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFN
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            95814..96776
                     /locus_tag="KRN00_000238"
     CDS             95814..96776
                     /locus_tag="KRN00_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1826133.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            97148..97780
                     /locus_tag="KRN00_000239"
     CDS             97148..97780
                     /locus_tag="KRN00_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1826134.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            98191..98283
                     /gene="kdpF"
                     /locus_tag="KRN00_000240"
     CDS             98191..98283
                     /gene="kdpF"
                     /locus_tag="KRN00_000240"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBH1826135.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            98324..100006
                     /gene="kdpA"
                     /locus_tag="KRN00_000241"
     CDS             98324..100006
                     /gene="kdpA"
                     /locus_tag="KRN00_000241"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBH1826136.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            100031..102088
                     /gene="kdpB"
                     /locus_tag="KRN00_000242"
     CDS             100031..102088
                     /gene="kdpB"
                     /locus_tag="KRN00_000242"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBH1826137.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIEVGNAGSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            102107..102733
                     /locus_tag="KRN00_000243"
     CDS             102107..102733
                     /locus_tag="KRN00_000243"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBH1826138.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDIVNVLKVNVEVAKILGLI"
     gene            102970..103878
                     /gene="cysK"
                     /locus_tag="KRN00_000244"
     CDS             102970..103878
                     /gene="cysK"
                     /locus_tag="KRN00_000244"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBH1826139.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            103905..104495
                     /gene="cysE"
                     /locus_tag="KRN00_000245"
     CDS             103905..104495
                     /gene="cysE"
                     /locus_tag="KRN00_000245"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBH1826140.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            104655..104843
                     /locus_tag="KRN00_000246"
     CDS             104655..104843
                     /locus_tag="KRN00_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH1826141.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(104897..105766)
                     /locus_tag="KRN00_000247"
     CDS             complement(104897..105766)
                     /locus_tag="KRN00_000247"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBH1826142.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(105963..107207)
                     /locus_tag="KRN00_000248"
     CDS             complement(105963..107207)
                     /locus_tag="KRN00_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826143.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINSKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            107498..107809
                     /locus_tag="KRN00_000249"
     CDS             107498..107809
                     /locus_tag="KRN00_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH1826144.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      107902..107994
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            108094..108888
                     /gene="thiD"
                     /locus_tag="KRN00_000250"
     CDS             108094..108888
                     /gene="thiD"
                     /locus_tag="KRN00_000250"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBH1826145.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            108912..109700
                     /gene="thiM"
                     /locus_tag="KRN00_000251"
     CDS             108912..109700
                     /gene="thiM"
                     /locus_tag="KRN00_000251"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBH1826146.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            109723..110355
                     /gene="thiE"
                     /locus_tag="KRN00_000252"
     CDS             109723..110355
                     /gene="thiE"
                     /locus_tag="KRN00_000252"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH1826147.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGKNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSASFETVKEIKEK
                     VDIPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            110494..110796
                     /locus_tag="KRN00_000253"
     CDS             110494..110796
                     /locus_tag="KRN00_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1826148.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(110862..111611)
                     /locus_tag="KRN00_000254"
     CDS             complement(110862..111611)
                     /locus_tag="KRN00_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826149.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIILIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(111605..112567)
                     /locus_tag="KRN00_000255"
     CDS             complement(111605..112567)
                     /locus_tag="KRN00_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826150.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNGLSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDSIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(112571..113029)
                     /locus_tag="KRN00_000256"
     CDS             complement(112571..113029)
                     /locus_tag="KRN00_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1826151.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNLPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            113385..113741
                     /locus_tag="KRN00_000257"
     CDS             113385..113741
                     /locus_tag="KRN00_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1826152.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            113813..114529
                     /locus_tag="KRN00_000258"
     CDS             113813..114529
                     /locus_tag="KRN00_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826153.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            114522..115346
                     /locus_tag="KRN00_000259"
     CDS             114522..115346
                     /locus_tag="KRN00_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826154.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYNLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            115358..116557
                     /locus_tag="KRN00_000260"
     CDS             115358..116557
                     /locus_tag="KRN00_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826155.1"
                     /translation="MKLKSKISIFIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYAKILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIENIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDDKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            116566..117378
                     /locus_tag="KRN00_000261"
     CDS             116566..117378
                     /locus_tag="KRN00_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826156.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVNVTGFSSFRNIMGSTESWFMFGIIACICYAFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            117389..>117946
                     /locus_tag="KRN00_000262"
     CDS             117389..>117946
                     /locus_tag="KRN00_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826157.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNIS"
BASE COUNT        47032 a        12430 c        20864 g        37620 t
ORIGIN      
        1 tactattata taaaagacct taaagataga aaactacaga aagaagccaa aatgtttttg
       61 aaaaaaatga aattttattg caaaaaaatc aaaatgaatt taacttaata gttataatct
      121 atttttagtg ttacaaatat acaatgtata ttatacaata taaaaaatac atttacttag
      181 aaatattatt atatttggat ttttggtttt tataattttt ttatatttaa acataactaa
      241 aaataaaaga ttactaaagc taagtagagt ttattttatt ttaataaata ataaagctat
      301 ttttctatat attggcataa tatatgctta tttaactatg aaattaaaat taaataggat
      361 taatgaggag gaaaaaaatg ggaagtaatg aactgaaaaa gactcttggc gtatcagcag
      421 cattatcaac tgttgttggt tccgttatag gagcgggcgt attttttaaa ccacaagcag
      481 tctatacatt aactggagga gctccaggtc ttggtatatt ggcatggtta atagctggaa
      541 tcataactat aacagctggt cttacagctg cagaggtatc agttgcgata ccaaaaactg
      601 gtggaatgat ggtatatata aaagaaattt atggagaaaa attaggtttt ttaactggat
      661 ggatgcaaat tgtattattt tatccaggga tgatggcagc attaggtgtt atatttggag
      721 aacaagcatc agcactaatt ggtagtccat cacttttact tccaatagca attggaatta
      781 tagtaatagt tgcagggctt aatatgttag gttcaaaaac tggaggagtc atacaaactg
      841 tttctacaat ttgtaagtta ataccactta ttttaataat ggttgttgga tttattaaag
      901 gtggtggaaa taatccaata cttacaccta tggttggtga aggattaagt ctgggtagtg
      961 tactaggtca agttttaatt gctatattat ttgcttttga tggatggatg aatgttggta
     1021 ctttagctgg agaaatgaag aatcctggaa aagaccttcc aaaagctata ataggtggat
     1081 tgtcagttgt tatggctgtt tattttataa taaatttagc gtatctttgg gtattaccag
     1141 ctaatgaatt agcaaattat gcttctcctg catcagcagt tgctgaagtt atatttggtt
     1201 caatgggtgg aaaaataata tctgtaggta tattaatttc agtgtttgga gcattaaatg
     1261 gatttttact aactggttca agggtggcat atactttagc tacagataag actttaccaa
     1321 agtatggtat attttctaaa ttaaattctg ctcaagttcc agcaaatgca atagcattag
     1381 tatctgttat tgcatctata tatgctttgt caggtcaatt taatttatta actgacttag
     1441 ctgtatttgc tacttggata ttctatgtat taacttttat aggggttatg aaacttagaa
     1501 agactcatcc aaatatacca agagagtata aagtcccatt atatcctatt gttcctataa
     1561 tagctatagc aagtggtata tttgttgtag ttaatcaatt gtgttttgca ggtatgaaaa
     1621 ctactatgat atctatagga ggtcttgtaa taacagctat aggcttacca gtgtatgctt
     1681 atatgactag aggagtaaaa agataaacca agtagtttac aaatgcttca taattaaaat
     1741 aaaagagact gtctcaaata gagataagtc tcttttttat tgttaaaatg gtaaagatat
     1801 gtttaatttt acaaaaaaag agcgttccat gaactaaaaa gtttatttta aggtattcat
     1861 tttattttta gttttttgat tataaaatta aacatctaaa aaattattta ttttaaaata
     1921 ctttatttta aagtgttttt tatcaaacta agtggtatct gtacaacaaa tattatacat
     1981 agcttttatg aaaattaaat ctttctgtta tatataatag aatattgtat tatatagaaa
     2041 atattacctg attaatatag tgatttataa atgagattag aaaattttat ttgataacaa
     2101 aaattagata atatgaatat ataatgtatg tattaaaaat gtggcaaata gttgttttgc
     2161 tatttattat ttgtttaata tttctaattt ataaaaaaaa aattataaat tttaaaaatt
     2221 ataaatgaca ttttaactag aattaattgt aaaaaacact atataatact caattttcaa
     2281 cattctatac aattatacag aaattataca gcataataat caccgaaata acaaatttta
     2341 aaaattaagc aaaacttttt gtcgaagttc aacgtctata tatatgtagt gtaaattttt
     2401 gggataaaat actacaaaaa tataaatgta aaaatatagt aatattggag gtcgaacgat
     2461 gagaaataaa aagaaaaaaa taaatagaaa gaagttgtat ttgcttttaa gtgctattgt
     2521 agtgtgtctg gcttttatag tagttggtgt tcgcgtcagc tctttaaata tgaaggaaaa
     2581 tgaaattagt agaaatgcaa aactgtcaag ttctactatt acagatatag tatctaatac
     2641 atcaatagaa gttagtaaag ggccaagtaa aagttctgga aaaatagcat acataactat
     2701 agatgatggt ccatctaaat ttactgacca gatgataaaa actttaaata aatacaatgt
     2761 taaagcaact ttttttatga tagatgggaa tatgaaggaa tatccacagc aagttaaaaa
     2821 tataattaaa aatgggaaca cagcaggttt tcatagtgta tcacatgata ttcacaagct
     2881 ttatgttact agtacatcag caaaagagga atttgataca aatgatcaaa ctttttataa
     2941 gataactggt aaacattcaa aagtaataag aataccttat ggaagcaaac catatacacc
     3001 acaagcctct tatcaggctt tagttgatgc tggatataaa atttgggact gggacttaga
     3061 tacagaagac tggagatcta attcttctca aattgtacaa aatgtaaaaa atcatattaa
     3121 gaatagaaaa ggtgaagata aagaccaact tgtagtttta atgcatgaga aaaaacagag
     3181 tgcagaagct ttagattcag ttttaaaatt cttatcagat gaaggttatg aatttgcgcc
     3241 agtagatcaa aaccaaatac caaaaaatta ttggttacgc aatttagagt agttaaaata
     3301 taagaatatt gattgatatt tttagaaatt gagaataaaa atgagtgagg tgtaggtata
     3361 ttgaataaaa aactttatat aggaatggtc ggaatattgt ctttgatgat ggttggttgt
     3421 aataaaagtt tagcaaaagt aaatgatgtg gaaatcacaa aagaacagta caaaaaaaca
     3481 aaagcagttt tatctgctac taataattat ataaatgggc agtctttaga tgaattagaa
     3541 aaaactttgg ataaaaaagg tagaaataaa ttagaaaatg ttataatatc gtttatggtg
     3601 gataatgaac ttttatatca agaggctaag gataaaggac taactccaag taaaagtgaa
     3661 gtagactcaa aatatcaaga actagaagat aagatgaatt tgaatacaag ctataaggaa
     3721 aaaatggaca aagcaggtgt tgataaagat tatttaaaac aagaaatatc tagagattta
     3781 gcaatagata aaaataaaaa ggcctttgaa gatagaataa acataagtga taatgatatg
     3841 gaagcctact atacaagtca taaaaaagat tttaatgtag aagaagtaag tgcttctcag
     3901 atacttatat cgactttaga taaaaataaa aaagaagtaa gcaaagataa aaaagaagct
     3961 ttgaagaaga aggcagataa tatattgact aaaatcaaaa atggagaaag ttttgaaagt
     4021 ttggctaaaa aatattcgga tgataaagca actggaaaaa atggaggaca gctaggatat
     4081 tttacaaagg atgataaaaa tgctgagttt acaaaggaag tgttcaaatt aaagaaaaat
     4141 gaagtttcaa atgtgtttga aactagttat ggatatcata tagtcaaagt tactgataaa
     4201 agagaaagac aaaaaagttt taatgagtgt cagagtttaa taagagaatc tattttaaat
     4261 gaaaagtata ttgagcatat aaaaaaactg aatgaagatg ctaaaataga cagatagaat
     4321 ttctaacagc tcaatcctag cctgtaatcg gagggagatt ttacaggaat gtttaagagt
     4381 ttaaagagaa cgaaagttga gaaatacatt atcgataata aagactcttt ttatagaata
     4441 gcatatagtt atacgaagaa tgaagaagat gccttagatg tggttcaaga agccatgtat
     4501 aaggcactat actcagtgga aaatattaaa gaagtaaatt atataaagac atggttttat
     4561 aaaattttag ttagaacgag tatagatttt attagaaaaa accgtaaata taataatatg
     4621 acagatattg accttataga tgagactgga gagtatgata aatatactga tttggattta
     4681 agaagagctt tggaagaatt acctattgaa tacaaatcta ttataatatt aagatttttt
     4741 gaagatttaa agattgaaga agtagcaata atattggatg aaaatgtgaa tactgttaaa
     4801 actaggttat atactgcttt aaaaaaacta aaattaaaaa ttgaagagta gggataaaaa
     4861 gaatgacaag caaagaaagg ttaaataagt taaaagatga gtatcataaa attccaatac
     4921 ccaagaaatt agatactata ataaatcatg aaaaaataga aaacatatat cgagagaaaa
     4981 ataaaaaagt aaatagatta agatttaaag ttgcaatagc ctttgcatgt atatttacag
     5041 tattagtaaa tataagtcct gtatttgcag acaatttttc taagatacct gtaattggag
     5101 caatagtaga agtaataact ataaaaaatt atagtttaaa aagtgaaaat tatgaagctg
     5161 agattgatat tcctaaaata cgaggtttaa aagataaaaa cttagaacaa agattaaaca
     5221 gtagttttat ggaagatgga aaaaggcttt atcatcaatt ccaggagaga atggagaaga
     5281 tacaatcatc aaagaataaa ggatataaat ctttaagttt gagttatagt gtaaaaaata
     5341 attctaaaaa atttctatca atagagatga caaaaaatga gatagaggct tcatcatatg
     5401 tgagtaaagt acattatact attgataaaa aaagacaaat agttttgact ttgccaatgc
     5461 tttttaaaga tgataagtat ataaaagtta taagtgataa tataaaagaa caaatgagag
     5521 aacaaatgaa aaaggatagt acaaaatcct attttataga tcaaaaaaaa gacttgcctg
     5581 ttgaagattt taaaacaatt aataagtatc aggattttta ttttaataaa aatgaagacc
     5641 ttgtaatttg ttttgatgaa tatgaagtag cacctggtta tatgggcgca gttgagtttg
     5701 taataccata taaagtaata aaagatttgt aaattgaata gtagtttata tataaatctt
     5761 ttaaggagga caatatgact acatataaaa aacttaaaaa atctatattt aaaattgcta
     5821 tattttcaat atgcttatta gtttcattag tagatacaaa ccctatattt gcaggtagtt
     5881 cctctaatga gacttcaaat agtgatacga taaaggtgtt aaatgctaag agtatcaact
     5941 ttaaacaaga caattatgaa gtgaatgtga gtattcctaa aataaaaggt ttaaaagata
     6001 aaactttaga gaataaatta aacaatgagt ttttgcaaga tgggaaaaaa atttacagtg
     6061 aatttcaaaa taaaatgaaa aaggaaaata ataagggtca tagataccta aatgtaatcc
     6121 ataatgtcaa aaataattct aaggactttt tatcaataga aatgacaaaa gaagagatag
     6181 aagcttcctc atctataact aagaagcatt acactgttga taaaaataga ggaatactat
     6241 taaatttacc aatatttttt aaagatagta gatatattag agctataagt gataatataa
     6301 aagagcagat gagaaatcaa attaagaaag atgatacaaa atcttatttt atagaccaag
     6361 ataaagactc gccagtgaaa gattttgaat ctataaataa gtatcaagat ttttatttta
     6421 ataaaaatgg aaatcttgtg attagttttg atgaatatga agtagctcct ggttatatgg
     6481 gagtagtaga atttgtgata ccaaataaag taataaaaag actaagatag atatatagaa
     6541 gatttttaga tagactggta aggagaatta tatgaatata tatgaacaag caataagatt
     6601 aatagaaaat aatgaggatt tcgcatttgc tacaataacg tctcattcag gttcaacacc
     6661 acgtgaaact ggagcaatga tgattgtgaa aaatgattct actatatttg gctcagtagg
     6721 aggaggtagt gtagaagcag aatgtataaa acatgcaatt aatgttataa aaaacagaga
     6781 atcaatgttg tataaattta ctctaaacaa atctgatgtg gcaaaactag gaatgatatg
     6841 tggaggtact ggagaaatac aaatagattt tatagatagt aaattaaaaa gtaatataga
     6901 aaaatttaat aagagactaa aggaaaatac aagtaaagca tatatatttg gtgcaggtca
     6961 tatttcaaga gatgttgctg tgatactatc tcttttagaa tttagaacag tagtaataga
     7021 tgatagagaa gaatttgcta atcatgaaag gtttccagaa tcagaagtag tagttttaga
     7081 ttcttttgaa aacataccag attttccaac tgacgaaaat agttatataa ttattttaac
     7141 aagaggtcat ctatatgatt caagtgcttt agaatgggct cttaaaagag aggctggtta
     7201 tataggtatg attggaagta gaacaaaaat tggattgact tacgaaaaac tcatgaaaaa
     7261 aggttttaag aaggaagaat tatcaaaagt acatgcacca ataggcataa aattgaatgc
     7321 tcaaacacca gctgaaatag ctgtatgtat agctgctgaa cttataaatt gtagagctaa
     7381 taaggaaaaa taaactaatg aacacaggga gtaaagatat tgatacttta aaggttaatt
     7441 ttagagggat tgaaataaaa gcagttttag tatataaaaa tagaaaaaat atttctataa
     7501 aaatagatcc atttggcaaa ataactgtaa tgagtcctcc taaaatatcc aaaaaaataa
     7561 taaaagatat aattattgaa aaaggagact ggatacttaa aaagtcagaa aaatataaag
     7621 gaagagagga agtatataaa caaagaatgt ttataactgg cgaaaaattt ctttatttag
     7681 gtgaagagta ccatctagtt ataaaagaac tgttgagaga ttctgtcaaa aaaagtaact
     7741 gtagaataac tattaacgaa tatcaaatat ttgttcagac aaatgataca agtacagatt
     7801 ttattaaaaa atctttaaaa tcttggtata agatggaaag tgaaagaata gtattagaga
     7861 gaatagattt tcttaaatta aattgtgaaa taatgaagca attagttcca gcgagtgtta
     7921 aggtaaaaga acaaaataag agatggggaa gttgtacagc tcaaaaaaat atttatataa
     7981 actcaaaaat atctatggca agattagatg taattgatta tgtaataata catgagttta
     8041 gccatttagt acatatgaat cactctaaaa aattctatga tttagtaaaa tccattatgc
     8101 ccgattataa agataaagaa aattggctaa aaataaatgg atataaaata ataatctgaa
     8161 aacgattatt ccaaaatata ggcgtaaagt ataaaagaag tattattgtg aaaaaaataa
     8221 ataatctgaa aattttaaaa aaagtcattg acattgtaaa tgatagggaa tataatctat
     8281 attaacaaca aaacagaatt aaaatataaa attaaaaaat taaaagcaat gacagagaca
     8341 acaatactaa tagtgttatc cacagagaac caatgttgct gagaattggt gttaacagta
     8401 gtataatgat cactctggag cttttgtact gaatattttt agtaagtaca aacgtatgtc
     8461 aacgttacat gactaaggtt aaggtaatta attacccgac ctgaaaaaag aggggtagat
     8521 gtatttttta tatctacaaa taaggtggta ccgcggaata taactttcgt ccttataagt
     8581 aatatttata ttgcttataa agatgaaagt ttttttattt taagcgatat aaataaattt
     8641 aatccatata aaattaataa aaaaataata aaaataagga gggattttta tggaaaatac
     8701 tgtatatgct aaattaaacc aaggaataga ttctttttta agagtggcta tgactctaag
     8761 aagaagagag gttgatatac aatcaataag tatgactgta gataatatga ataattcagg
     8821 tataaaatta atagtaaatg aagaaaagac atctttagat tctgtcttaa accatatgaa
     8881 aaaactacat gatataagag agataactgt tgaaagaatg agacattaat taaatatatt
     8941 ttataaaact aaagataaat atgcttattt taaaataaaa aactaaagat aaatattaaa
     9001 taagaaaaat cttagattaa aatataagtg tcattgaatt tattagttta tcacagttaa
     9061 taaatttatt agtttgttgt agctaataaa aactgaaaat tctaaaatta taattgtaag
     9121 attatataaa tttagaattt aaatctgttg aataatatta aaacaatgat aatgagtatg
     9181 aatttctaat aaaaataaat atcataaaaa taagaaaaag tattgggagg aaatgaaaat
     9241 ggcaagaatg tattatgaaa aagatgtgga tttagaggtt ttaaaaaata aaaaggttgc
     9301 agttttaggt tatggaagtc aaggacatgc acatgcacaa aatcttagag ataacggtgt
     9361 acatgtaatg ataggtcttt atgacggaag taaatcagca caaaaagcaa aagaagatgg
     9421 atttgaagtt aagagtgtag cagaagctac aaaagaaagt gatttgacaa tgatgttaat
     9481 gcctgatgaa aaacaaaaga aagtttatga agagagtgta aaggataact taaaagaagg
     9541 tcagacatta gcttttgctc atggattcaa tatacattat aatcaagtac aaccaccaga
     9601 atttgttgat gttgtaatgg tagctcctaa aggacctggt cacttagtta gaaatgtatt
     9661 tacaaaggga agtggagttc ctgcactatt tgcagtatat caagactaca ctaaaaaagc
     9721 tacagagaca gttttagcat atgcaaaagg gataggagca acaagagcag gtgttttaga
     9781 aactactttt aaagaagaaa cagaaacaga tttatttgga gaacaatcag tactttgtgg
     9841 tggaataagt gaacttataa aattgggata taaaacgctt gtagatgcag gttatcaaaa
     9901 agaagtagca tattttgaat gtttacatga aatgaaacta atagtcgacc ttatatatga
     9961 aggtggattt gaaagaatga gatatagtat aagtgacaca gcagaatatg gagattatgt
    10021 atctggtaaa agggtaataa ctgatgctgc aaaacaaggt atgcaaaatg ttttagagga
    10081 tatacaaaat ggaaaatttg caaaagcgtg gattaaagaa aatgaagaag gacgtgaaaa
    10141 cttcctaaaa actagagaag aagaatataa tacagaaatt gccgaagttg gtagaaatct
    10201 aagaagtatg atgtcattct taaaataaat atatattaaa tggattagtt tgagggaaag
    10261 agtggtgtat agtagtgcgt atgaatggag caaaggtaat tttagaatgt ttaaagaaag
    10321 agggaattga cacaatattt ggatatcctg gtggagctgt gatacctctt tatgatgctc
    10381 tatacgatta ttcagatgat tttaaacata taaggacatc ccatgaacaa ggtttagttc
    10441 atgctgcaga tgggtacgca agaagtacta atacagtagg agtttgtttt acaacatctg
    10501 gtccaggagc aacaaatgcc ataactggaa tagcaacagc ttttatggat tcttcaccta
    10561 tggttgtaat ttcagggcag gtgccaacta gtttattagg aaaagattct tttcaagaaa
    10621 ttgacataac tggagcaaca ttatctatga caaaacataa ttatttagtt agaaacacta
    10681 aagaattagt tcctacaata aaagaagctt ttagagttgc aaattcaggt agaaaaggac
    10741 ctgtacttgt agatgttcca aaagatttat ttttagcaga aatggatttt agtggtgagg
    10801 actatgattt atgtcaaata gatgattata tggattataa gagtgatttt gatctagatg
    10861 atgaaactaa tattaagctt ttaaatgaag caatagatat cataaaagaa tctaaaaagc
    10921 ctgtaatata tgcaggtgga ggtgttaaat cttcagacag tgaggaaatt cttgaaaaat
    10981 ttgcaactaa gatagataca cccgtactaa atacacttat ggggcttgga aatatagata
    11041 gaaagaatga actatctctt ggaatggttg gaatgcatgg aagtagagaa agtaatttag
    11101 cactttctaa ttcagattta gtgatagcga taggtgcgag atttagtgat agagtgataa
    11161 gtaaaagttc tgaatttgct aaaaatgcaa aaataataca catagacata gacccatctg
    11221 aaataagtaa aaatatagaa tctaatgtat ctttggttgg agatgtaaag ctagtcctta
    11281 gtttattaat tgaaagggtt gaaagtaaga ataatagcaa ttggaaagaa gagataaaga
    11341 catttagaaa gagtgagggt gtacaaacat atgaatttca tccacaaaat atacttaaaa
    11401 aaataaatga aaaatatgaa acattaaaga aacccactgt ggtagtaact gatgtcggtc
    11461 aacatcaaat gtggtctgct aaatactgga attttaaagg taataaaagt tttataacat
    11521 cagcagggtt aggaactatg ggatttggtt taggtgcagc tattggaact aaagttggta
    11581 atgtagataa aaatgtagtt ttagtcactg gtgatggaag ttttagaatg aactgtaatg
    11641 aactagctac agttgcaaat tataatgtac ctatgcttat tttactactc aataatagaa
    11701 cattaggaat ggtaaggcaa tggcaaaagt tattttccaa tcaaagatac tctcaaactg
    11761 acattaatga aaatgtggat tatgttaaac tcgtaaatgc atataatatt gatggatata
    11821 aggtatccag tatggaagaa ttaggaaagg cgctagatat gatagatttt aataaacctg
    11881 tatttttgca atgtgatata gataaggatt atgatgttta tcctattgta gcacctaatg
    11941 atgcattgga aaatttgata tgtaactaaa acttatactg aatattgata aaatttttta
    12001 ttaaattttt attggtattc agtttttgtt gtttagagat agattggcat tttttatttt
    12061 ttcaaataaa tcaatgacta tataattaag aacttattaa attttaatta tataatttgg
    12121 aatagtatta caacttaagt aaatattaag ttttatttgt tagatttatt attaatacct
    12181 tatattagtt atggttgtta tatactctaa agccttgaaa ttacaagtgt atagctgacc
    12241 atataaattt gataatttta gcttttaaaa tagataaatt agattttgcc acccatttgc
    12301 caccgtatta tatttttggg tggcaaactc taatttgtaa ttttttcaaa tatatctaca
    12361 gtttcatttt tcattttatc agttacatgt gaataggtat ccattgtagt tgatagttgg
    12421 ctatgaccta aacggttttg tatgtcttta atgttagcac cattttctaa taatagggta
    12481 gcatgtgcat gtcttaaaga atgaaaatgg aagtcattgt ttaaagctac tcgaatttgt
    12541 cttactatag tgtctaaagt gtgagtattc acttgttgac cattttcttt ggtacatacc
    12601 cagtcactat caaagtaaaa ttctccatat tttaatttca ttttcttttg atataattta
    12661 tgttctttta atgcctttat taaagtgtca cctgtaaata tagttctgca agagctttct
    12721 gtttttggtt gccctaattc aaacattcca tttggttttt taatcaaagt atgctttact
    12781 gtgatagttt tattatcaag gtctatatta tcccatttta gtgcaataat ttcacccctt
    12841 cgcataccag tatgaaatcc aattagtaaa actatacgtt gaaatgaatc ttgaggaaat
    12901 atatttagta tttgattaaa ttcttctaat gtaatagttt taattttatt agtttctgtt
    12961 ttagatttag tttttggtat gctcacatat tgcatagggt tttctcgtat atgtttgtaa
    13021 ggatggactg ctgattttaa tgacctatgt aatatggctt ttaatacttg taatgtattt
    13081 tgagagtaat cctctttgta ctttttattt atgaagtttt gtagtattgc aggagttaaa
    13141 gcttttactt tgtaagctcc tagctttggc tttatatgtt tttctatgtt tattcggtag
    13201 ctttcttgag tgttgtattt acagttaagt aagacatatt ctttgtacca aaagtctaag
    13261 tagtctgata aactgatgtt gctttcttca aatactatgc cagagttttc atattcattt
    13321 agtgcttctc ttaaggcttt ttctgcttct tttttagtat tgcctccaac tctttctact
    13381 ttttttcttt ttccttctac tatgcctagg tcaaagtagt aataccattt gttacttctt
    13441 tttcttactc cacctttcat aatagtatcc ctccctttta gaatgtatgt ttgtttggtg
    13501 tttatataaa agagcagatt aactgctctt tatatacttt tgttatgtac aatattatct
    13561 taattttgtt tatctggttt tcacttagtt attttcttaa tattcttaca attttttagc
    13621 ttttatgtgt agtttattat aataatattg aaatatatat ttattaagta aaaaatctat
    13681 aaaagtagaa taaatgagtt taaaaaatat cctcatatat gtagaaattt ggcaaattag
    13741 ttaatactaa aaatctatta tttcctaagt ccaacatgct tttctttttt gatagaaatt
    13801 ctaatctttt tagtaagaag ttgatgctaa cttgtaattc ttcagctatt tcgtatacac
    13861 ttgtagcgtg tgaattaata acatgtatta tttcttcttc tgttataaga aattcacatg
    13921 cccattttaa tgctttgttt tcagttttgt ctatcaagat tttatttttg taactgtttt
    13981 ttgaagatac atagttccca acactggtaa aatgatgtcc taattcttct gctaagattt
    14041 ctattagttt agcattgttt tgttttaatg aattaagtaa tgatataatc tttagtcctt
    14101 gtctgtttat atacaatcct tttatgtcat ctgctatttt gtcagtgtag taaatttcta
    14161 tctcttcatt atttgctaag tctaaaagtg cgtctagttt gttcattgaa atccccctat
    14221 aaaaagaatg tatttttgat ttttgttata tataaagagc aggtgtgaac tgctctaaat
    14281 attcattttt tatccaaaaa agattggata attttagctg tagacaaaat atggattata
    14341 gtatatgatt ataatataat tacatataat atatgtaagc acttacaaat gtgtgttagt
    14401 atagttagca ctaaatttgt atttgtgctt aaagcgatta aaggagtttt ggagcggtgg
    14461 gtagagtttt actcactata accaagactc ttttgcatat tagagtattt catgtagtca
    14521 tatattctaa taagccttct taaatttgtt ttttcgcttg tttttgcaga ctctaaaata
    14581 ttaggatttt cctcaaatat tttcttaagt agattttcta actgttcagt gtcaatttct
    14641 ttttcttcta aaaaagcaat aagtcttgta gctttttcaa atgattgatg ttcatcattc
    14701 caaataccat aaacacttct attttttatg taagtattat ttctattttt tttaatacta
    14761 ttgctaataa tattttcaaa gtcactttct agtgcaattg tcctataatc tggaaattca
    14821 agtgtgctat taaaaagatg tttatttaat ggtaatttat tatattgctt aattaaagat
    14881 ggataagcat attcaagtaa ttcatctgat gaaaattcta agtcattcat gactatatca
    14941 cgataccatt catcaaaact taatcctttt aatcctttaa gaccaaaatc acttgccttg
    15001 ccaactgcta aaactaaatc ttcatctttt attcttgtat catcaacact accaacccga
    15061 attttagcag taggtttgtt agtaattgtg aaatcgtaaa attcttgttt gaacattctt
    15121 aatattctaa ctggtaattt tgattttttt tcagataatg cctcatagag taaattaaaa
    15181 tcctccagtt taattttagt catagtaatc attttattat caaaagcaat tgtatgactt
    15241 gatatttcta tatcattaaa gtttttttca tactcaatga atatgaaacg ttcctcgagt
    15301 tttttagcat tttcattaga tagacaatta actatagcat taagtatttt ttttatattt
    15361 acatctgtaa cagagtaacc aataaatatg ataggaaact caacaaatat agtcattagc
    15421 ttagctgcca agtaggcact tttgctgtca aagtctatat aatcagcttc atttattaca
    15481 atactatttg gagaagaaac acatccatga attttataaa tttctgcaat accttgtata
    15541 gatgaaaaaa ctaaattttc ttgacctata tatgttgtat aattatcaac gatagtttcc
    15601 aaaaaacaat cataatttgt tgtaataaat cctgataaac tttttttaga gatattacta
    15661 agtttttcaa cttcatcttg atatttatct actattttag aattattttt aatatacata
    15721 gcaatttctg ccttaaatgg agaaactcct gatttaacaa tatctaaata cttagagtct
    15781 aagcttcgta tagaagaatc tgaaaaccat tttttattaa aatcattttc aataagttct
    15841 gcaattctag gatttatacc catttttggg ttctctgatt ttgctttatt tttataactt
    15901 gtatatataa agtcatcatt actaattttt tctgcaaaga cttttagtaa atcctcccaa
    15961 tttggaagat tatagtatct tctagttaaa ccagaaccaa caaataaaaa tggtgtagca
    16021 ttaaatcggt ttatgacatc tgatattata gatttcatat aatttatcac ctacttttaa
    16081 tttatttttt atacttattt attaaaaatt caatataatc attgagttgt tcttgagctt
    16141 cctctggtaa atctttgtga ggattaactc tatgtgcagc tacagtgtct atatcatttt
    16201 ttacaataga cctacctaat aaataatcag tagtcacatt aaatatttca gcaaggctag
    16261 ataacatata agcatcagga actgtctttc cttgttcata ataaccataa gcgcttttgg
    16321 ttaagtttaa tttatttgca acatcttctt gagtcatatt tttttcagct ctaagttctt
    16381 ttagtctttt ttgaaataat gtattattac aagaagtttt gctagaaata ttgcttgctt
    16441 tattatcata cctacctatt aaataatcaa cagtagtgcc aaaatattca gctaaactag
    16501 ataacatttc tggggtaggt gttcttttac cttgttcata aaatccatat gcactagtag
    16561 ttatgttaag atagttggca atttcttttt gcattacacc tttttctttc ctaagaaatt
    16621 tcaatctatc tgataaaatg ctcatataat cactcctctt aataaagttg cctttattaa
    16681 ataatacaac aaatagttgt aaaatgaaat aaaaaaataa aaaaactatt tacaaacaac
    16741 atatagttgt gtattatata agtataaaca acaaaatgtt ggcaaggagg atatagcttg
    16801 aacaatctaa aggaacttag gacagaaagg aatttaaagc aaaaagatgt tgcattaaaa
    16861 gtaggtataa ctactagtta ttatggaatg attgaaagtg gaacaagagt accaagttta
    16921 gcaatagcaa taaaattatc taaatgtttt ggagtatcaa tagaaaaaat ttttttaaat
    16981 acaaatacaa caagatgttg tttaaaagag aggagttaaa tatgaaagat ttaaaaatag
    17041 taaaagttaa taataaacta acaactgata gtagggatat agctctaatg gttgaaaaag
    17101 aacacaagat tttactaaga gatataagaa actatataaa tcagatggaa gaagccaata
    17161 aaaacatgag tacagatttg tacccatctg attattttat tgaaaatact tatttagatg
    17221 attataaaag agagaagcca tgctatgcaa taacaaagat aggttgtgac ttcatagcaa
    17281 ataaaatgac aggcataaaa ggtacggcat ttacaggaat atatacaaaa aaatttgaag
    17341 aaatggagca agtattaaaa aatgaacaaa ctaaactacc aactacatat aaagaagcgt
    17401 tacaacatct tatagagcaa gtagaagtaa atgagcagtt acaattagaa ggtaaaatga
    17461 aagaccaagt aataaaagaa ttaaaaccga aggcggatta tacagatatg atacttaaaa
    17521 acaaaggact tgtcacaata actcaaatag caaaagacta tggaatgagt ggaaaagaaa
    17581 tgaataaaat acttcatgaa agagggattc aatataaaca aagtggacaa tggcttttat
    17641 ataaacaaca tcaaggggaa gggatacact cattcagaaa caatagacat aactagaagt
    17701 gatggaatga ctgatgtaaa aatgacaact aagtggactc aaaagggaag attgttttta
    17761 tatgacttat tgaaagtaaa taacatatta ccagatatag aaaaagagta tagttatcaa
    17821 acttcaatgt tgggttagta ctttgaaaaa taaatacaga atattcaaaa agaggtgatt
    17881 taaaggttga gtaatagaaa gaagtatacc ttgagtatta cgaaagaatt atacaataaa
    17941 tgtaaagaaa aagctaatca aagaggtatg tcagtgaatg attacatact atcagtgatt
    18001 agcaagagta tataaattat tcttcaatat taattttaat ttctcctttt ctttgctcat
    18061 aatcttcaat atgttttttt attatttgtt caatttcctt attagcagaa cgaccttcgc
    18121 tttcagctat atatttaatt ttttcaagca gaactctgtt tattcttaaa gtgtatttag
    18181 gtagtgaagt tgacataata atacctcctt tttaaagtct aaatgatgtc ataattatat
    18241 cataaaaata attaaagaaa gagggagata aaatgaaaca tgagcaaaca acgcttcgta
    18301 taccagaaga cttgtacaaa gcgttgatag atttaagtag tgaaatagga atgcctattg
    18361 catctattat aataattgca tgctggttgt atatatcaaa gataaattaa ccaatgagat
    18421 atgcaaaatg aatgcacagc attatttatt agagaattga ctgataaatt attttcttta
    18481 gctgttttct ctagtaattc ttttagaaca ctaggaatcc tgagagtaga acgaacgcta
    18541 tcatcacttt tatatgagat tgatttaagt tcattaactt ttgaatttct aataatgtca
    18601 ttaatagcat atagaataag cgaagattta agaatacctg tttgataaga aattttttct
    18661 aaattttcat ttaatggtgt atatattctt acagtaatag tagtcatttt gacacctccc
    18721 taatgacatt atacagaaga tgtttagaaa agtcttgaca gtaaaacagt gtcataatat
    18781 aatggatata gacagtgaaa cggtgtcata aagagaggag gaataagaat ggaaaaagta
    18841 agaatgacag taagacttgt accaaaatta aatcaagatg tgcagaaaat agctaaaaaa
    18901 tgtggaaaaa gtaagaattc tattatcata gatgcttgtt gggattttgt tgagaaaatt
    18961 aaaaaagaaa ataaatttaa tatagaaagc gaggaataag tatgaataac ttaacaatta
    19021 tcaagcaaaa caataaatat ttagttgaga gtagagaggt agcagaatta atagaaaaag
    19081 accataacca attattaaga agtataagag gatatataag tgtattagag cagagtgcaa
    19141 aattgcacac tgatgatttt tttattgaaa gcacttataa gaatgaaaat aatcagaaat
    19201 atccttgtta tctattgact aaaaaaggtt gtgatatggt tgcgaataaa atgactgggg
    19261 aaaaaggcat tatatttact gctatttatg tggctaagtt tgaagaaatg gagcaagtat
    19321 taaaaaatgg accacaacct aaactaccaa ctacatataa agaagcatta caacacctta
    19381 tagaacaagt agaagtaaat gagaaattac aactagaaag taaaatgaaa gaaaaagtaa
    19441 taaaagaact aaaaccaaag gcagattata cagatatgat acttaaaaac aaaggtctag
    19501 tcactataac tcaaatagca aaggattatg gaatgagtgg aaaagaaatg aacaaaatac
    19561 ttcatgaaag agggattcaa tataaacaaa gtggacaatg gcttttatat aaacaacatc
    19621 aagggaaggg atacactcat tcagaaacaa tagacataac tagaagtaat ggaatgcctg
    19681 atgtaaaaat gacaactaag tggactcaaa aaggtagatt gtttttatat gatttattga
    19741 aaacaaataa catattacca gatatagaaa aagaatatag ttatcaaact tcaatattag
    19801 gttagtactt tgaaaactaa atacagaata ttttggaaag gagagattga attggaaaat
    19861 aagaaaatag aagaaataga gaaaagaata accatgcttg aaaatcaatt gcaagcacag
    19921 ttatttagtc agataacagc tcaatcaaat agtgatttta tagattatat gtaccaatgt
    19981 atagttttgt atttacatga gatgaataaa agtgaaaaaa gaaaaattag tgaaattact
    20041 aaagaaagaa tcagaaaata agaatgataa ttacaatata aaacctattc ttctagcagg
    20101 ttttgaaggg tcagttttct ttactgaagt tatcataaag tttatctgtg atgtgtgttg
    20161 aagaatttca gaataaactc catttactat gccgtagtag tgaattagac aagggttatg
    20221 ataacctact tcttcaacaa tcattaatac atcttttcca aagttagtca attttagtgc
    20281 aatttcatgt tcatcatcaa gttctttttc aaattcctct atagatttaa gaataatttt
    20341 atattgaaat tcagcatagt aaaaatactc tgtgttagaa gtatcagaga ctgtctttct
    20401 tatactttct tgtaattctt tagatatatt gtttgaaaac tgcataatac accatccttt
    20461 tgaaaatttt ggaatttatt ccatgtttat attataccat gtagaactga ggtgaataca
    20521 atgttaatag gcgacaatat aaagcaaata ctaagaaaaa gagatataaa accttataaa
    20581 ttggcaaaag aattggatat agatgtaagt ggtttatata aattactgtg aaataaaagt
    20641 tctaatccaa ctatagatac tctaataaaa ttagctgatt gtttagatat tacattagac
    20701 gaattggttg gaagataaat aattgaaaag aggggagagc attttcacat ggatatttct
    20761 gaaagcataa caaaacaatt tagtgatagc ttaaaaagct taatagaaat agagataagt
    20821 aaacaagaga cagatagagt taagagtcaa actattgaac aaaaggtaaa ggtactggag
    20881 cctaaagata tagttgtttt aataaaaaga ggttatccaa attatctaat aacagtagaa
    20941 gaagcaaggg gaattttaaa gttagataca gcctttatgc gtaggttagt aagcacaggt
    21001 ttgataaaat cactagttag aggtgatggt agaaaaattt caagatatga agttgatgat
    21061 tttattgaaa gaaatcaagg taaaaatttg gatgaacttt taaaagcagt agagaggggg
    21121 gatgaaattg ctgagtcttg atactaataa taagaatgta gtaactctta aaaaagatgg
    21181 aaaagttata gcagatatag tatttaaaga tattaaaact ggtaagaaaa tatcggttgg
    21241 aatattaaat aaaaaagtgt tggtaaaata accaacacac aaaaaaataa aaaataaaat
    21301 ataacacaag taaagtataa cacaaaaagg agatatttaa aatggttgaa gttaatgtaa
    21361 atgtaaaagt taaagtagaa gcaccagaat ttacaaatgc actattagta gtggcgaatg
    21421 ctttaggagg tcttaatcta ggaaaagcaa tgcagataga acctataaat ataacagata
    21481 tgaaagaaga gaagaaagtt gaagttaaaa aagctgaaaa gattaaaaag gtagaagtaa
    21541 aagaagacgt taaagaagaa atagcagaag caaaggaaga aatagaaaag aataatgaaa
    21601 atacaactag tgaagttaaa tacacaaaag aagaggtaag aactaaggca gcacaagtaa
    21661 gtaagtcagg taagaaggat aagcttaagg agttatttgg tgaatttgga gctagtaagt
    21721 taagtgaagt aaaagaagaa gattattcag cttttatgaa caaattagaa agtttatagg
    21781 gggtacataa atgccattac aacatgcaag acttagtgcg agtggagccc atagatggct
    21841 tcactgcact cctagtataa aattagaaga aaactatcca ccatcaacta gtatatatgc
    21901 agaagaagga acagttgcac atgaattagc agaagttaaa ttaatgctag agtatgaaaa
    21961 aataagtaaa aaggcatata atgcaagaat taaaaagata cagaaaagtg agtattataa
    22021 ctctgaaatg gaggactata tacaatctta tgttgagaat gtagttgaat tagtaaatga
    22081 tagtaaagct atatgtgatg atgtaatagt gatgttagaa gaaagactcg attttagtga
    22141 gtgggttcca gaaggatttg gaacaggaga cgttgttgta atatctgatg gtatacttca
    22201 agttatagac ctaaagtatg gaaaaggttt agaagtttca gctatagaga atcctcaact
    22261 tagactatat ggtttagggg catataatca gtttgaaatg ctatacgata ttgatttaat
    22321 taaaacaaca ataattcaac ctagacttga taacatatca agtgaagaaa tagaagttac
    22381 taaattactt acatgggcag ataatgttaa gaagaaggct caaatggctt ttaatggtga
    22441 aggagagttt gtaagtggca gtcattgtgg attttgtaga gctaaaaatg attgcagaaa
    22501 aagagctgag gataacctta aactagctag aaaatatgat tttgctgaca catttgctct
    22561 taataaatat gagatagcag atattttagg ttttgctaag aatatacaag attggttaaa
    22621 ggatgttcaa agttatgcac tagaacaagc tgaaaagcat ggtgttaaat atccaggata
    22681 taagcttgta gaaggcagaa gtaatagaaa gtatatagat gagcaagaag ttgctaaggt
    22741 tttattaaat tcagattatg atgaagaaaa aatttataag ccaaggacct taaaaggaat
    22801 tagtgatatg gagaaagcta taggtaaaaa gagttttgct aaactactaa gtgatttaat
    22861 tataaaacca gttggaaaag ctactttagt agtagaaagt gataaaaggt cagaaattaa
    22921 tagtatagat tcagcgaaaa aagattttga aatataaatg ggggatatta catgccatta
    22981 gatgcaggta taaaagataa attagatgaa agcataagta taattttaga tttaaaggat
    23041 agaaaaaaga gtatcgaaaa agatttagat tatgaaaaag ataatttact agatatgtta
    23101 aagagactaa atattacaga atataactca actgaagaaa atgcaaaagt tacagtgatg
    23161 gattttaaaa gagaaagttt aataaaggat aaagtgatgt caactttcct cgaagtaaat
    23221 gacaatcatc ttgatagagt gtatatacca gaacatataa aagttagtcc agtatgcttt
    23281 gtatcagtaa gagcaaagga taattaaaaa tatttaattc ctagtagcta taaaaagatt
    23341 taaaagggga tataatttta tgagtaatca agaaataact aaactagttg aaaataattt
    23401 gaatcttgta cattttagta taaatagatt ttttaagtct tatgtagagc aacatccata
    23461 cttatatgaa gagttttatc aagaaggatg tattgggtta tataaagcag cattaaatta
    23521 tgatagtaac agaggcaagt tttctacagt ggctgtttct tacataagaa tagaaatgtt
    23581 taaagctttg cgttatggcg aaaaacatta tagaaactct atagaaggtt tagatgtaag
    23641 tgtatttgaa gatagtaaaa gaccattaaa agatatacat ggattttatg aaattcaatt
    23701 taactatgat gttgattata taagaaaaat tgcaagaaag tcatatttaa aagatattga
    23761 taaaatagta gattggattt tacaagataa aaagatatct gatataggag agttattaaa
    23821 tgtttcttca acagttattt gtggaagaat taaattgttt agtaagcaag ttagagattt
    23881 agataaattt ggagaaataa cttcaaatat aaaatcaata taccaaatat aaaaatatta
    23941 ggaggaagaa aattatgagt aattcagtac aatcaacaaa ggtagtaaca ggaaaggtaa
    24001 gattaagtta ttgcaatatc tttaaaagca gagcaatggt agaaggtgca gagcccaagt
    24061 attcagtttg tattttaata ccaaaatcag ataaggtgac tttaggaaga ataaagaagg
    24121 ctattgatgc agctaaagaa caaggtaaaa cttctaaatg gggtggaaaa ttaccaggta
    24181 atttaaaaac acctattcgt gatggagacg cagaaagagc tgacgaagca gaggaatatg
    24241 taggaatgta ttttttaaat gcaaatagta ctcaaaagcc aggaatagtt gataaagact
    24301 taaatgaaat attagataat acagaggtat atagtggttg ttatggaaga gttagtataa
    24361 actttttccc atataatagt gcaggaaata aaggaatagg ttgtggctta caaaatgttc
    24421 aaaagttagc agatggagaa gtacttggag gagctagagc tagtgcagaa gcagatttct
    24481 cagatgactt tgaatatgaa gatgaagaag aggacttctt aagttaatga ggaccttatc
    24541 aattgatata gaaacatata gtgatttaga tataaaaaaa gttggagtct acagatatgt
    24601 agactctgct aattttgaga tactgttatt tgcctatgct tttgataatg aagaggtaaa
    24661 agttattgat ttagtaaatg atgaagagtt accaaaagaa gtaatagaag ctttaaatga
    24721 taataaagtt ataaaatcag catttaatgc taattttgaa agaacagcaa taagtaaatt
    24781 tttaaatatt aatttaaaac caaatgagtg gtcatgtaca atgataaagg cgttaacact
    24841 aggacttcca ggaagtttag atagtgtgtc taaggcttta aagtttaatg aagataaaca
    24901 gaaaatgaaa gaaggtaaag cattaataca atatttctgt aaaccttgta aggctacaaa
    24961 agttaacaag ggaagaacta gaaatttacc aatacatgat atggaaaaat ggaataaatt
    25021 taaagaatat tgtaaacaag atgttgtagt tgaaagagaa ataagaaaca aacttagtaa
    25081 gtataagact accgaaagag aaattaaatt atggtattta gaccagagaa ttaatgatac
    25141 tggtattaaa gtagatacag agttaataga gaatgcaata gaatgtgata aaagatatac
    25201 tgaaaaactt acaaaagaag caattaaaat aactggtcta aataatccaa atagtccagc
    25261 tcaattaaaa aaatggttaa gtgataaagt tagctttgag attacaagcc taacaaaaga
    25321 aagtattcca gaaatattaa aacaagttga tgatgaaaat gtagttagaa ctttagaact
    25381 tagaaaatta atgtctaaaa cctctataaa gaagtatgag gctatgaaat tagctaaagg
    25441 taatgacaat agagtaagag gtctactaca gttttatggg gctaatagga ctggtagatg
    25501 ggcaggaaga ttagtacaag tacagaattt accacaaaac catatagaag atttagacct
    25561 agctagaaac ctattaaaag aaggtgactt tgatttaata gagcttttat atgatagtgt
    25621 accagatgtc ttaagtcaat tgataaggac agcttttata ccaagtgaag gtcatagatt
    25681 tatagtatca gattttagtg caatagaagc tagggttata gcttggcttg ctggtgagaa
    25741 gtggaggctg gatgtgttta attctcatgg aaaaatatat gaagctagtg ctagtcagat
    25801 gtttaaagtt ccaatagaaa gtattaaaaa aggttctgaa cttagacaaa aaggaaagct
    25861 agcagaatta tcgaatggat atggtggaag tgtaggggcc ttaatttcta tgggggctat
    25921 taaaatgggg cttaaagaag aagagcttca acctattgtt actgcatgga gaaatgctaa
    25981 tccaaatata actaagtttt ggtgggatgt agataaggca gctaaaaaag ctataaaaga
    26041 taggactata gtagaaattc aacatgggat taaatttatt tataatccag gcgttttatt
    26101 tatagaacta ccaagtagta gaagattatc gtatctaagg cctaagatag agccacatac
    26161 tacatttagt ggagataaga taacatatga aggtatggaa cagacaagta aacaatggaa
    26221 aagaatagat acttatggac ctaagttagt tgagaatatt gttcaagcta cagctagaga
    26281 ttgcttaaga gaggctatgt ttaatgtgac agatgcaggt tatagcattg taatgcatgt
    26341 acatgatgag cttgtaattg atgtagataa aaaaggaggt tctttagaag aagttaacag
    26401 tattatggga aaagaaatat cttgggctaa aggtcttcct cttaaagcag atggatatga
    26461 atgtgattat tataagaaag actaggtgat tgatttatgg atataaaggc cagtgaaatt
    26521 gaacacataa atgtaagaca tgatggccaa ctcatgctgg ccataggaaa aaataaatta
    26581 gaaacacatt ggaaaaataa aagtatttta tggtccgaac ttgtaaatag attaagtaaa
    26641 acattaagaa ctcaagaaac atatacagaa tataggaaga tgtcaaagac tgaaaaagat
    26701 agagttaaag atgttggtgg atttgtaggt ggaagcttaa aaaatggaag acgaaaagca
    26761 gagaatattg caaatagaag tattataact ttagatatag attatgcgaa taaagatata
    26821 tgggaggata taacattatt aaatgattat gcttgtctta tgtattctac gcactcacat
    26881 actgagaata atcccagata tagacttgta atacctttaa ctagaccagt actaccagaa
    26941 gaatatcaag caatttccag gatgatagcc gatactatag gaatagatat gtttgatgat
    27001 actacatatc aacctcatag acttatgtat tttccaagta cttcaattga tggagactat
    27061 atatttaaat ttcaagatgg agagttttta aacccaaatg aaatactaga tttatattta
    27121 gactggacag atgtaagcta ttggccagaa agttcgaggg agaggcaaaa gtttaataca
    27181 caattaaaaa aacaacaaga ccctattgaa aaggctggaa ttataggtgc attttgcagg
    27241 tcctatagta taaaagaaac tatagaaact ttcttaaatg aagtatatat tcctggtatt
    27301 gatgaaacca ggtatacata ttcagaaggt agtacaagtg gtggagtagt tatttatgat
    27361 gacaagtttt catatagtca tcatggtaca gacccagcaa gcggaatttt atgcaatgct
    27421 tttgatttag ttaggataca taaatttggt gaacttgatg aagatgctaa acccgaaacg
    27481 cctgtaaata gattaccttc atttactcga atgagcgaat ttgcaagcag tgacactaaa
    27541 gtacgaaaga ctataggaag agaaaacctt gataaagcta aggatgattt tggtgatata
    27601 gattttgaag atgatgaatg gttaactagg ttagattatg acaataaggg aagttataag
    27661 aaaacaacaa acaatatctt aatgtttata gaaaatgacc catatttgaa aggaaaaata
    27721 gcttataatg aattttcaaa tagagctgtc gttttaggta agttaccttg gagaaatgat
    27781 gataaattaa atgattggaa tgatagtgat gattctgggc ttagacatca tatagaaaca
    27841 atttacaata tctcatcacc atcaaaagta aatgatgctc taataattgc ttttgaaaat
    27901 aatacttttc atcctataaa agattattta aattctttaa agtgggatgg cattaagaga
    27961 gtggatacac ttttaattga ctatttaggt gcagaagata accactatac aaggactata
    28021 ataagaaaag ttttagtagc agcagtagca agagtattta atccaggaat aaagtttgat
    28081 aatatgatgg ttttatctgg tcctcaagga atgggaaaaa gtacttttat taaaaaactt
    28141 ggtggagact ggtattctga tagtttaact actgtacaag gtaaagaagc gtatgaacaa
    28201 ttacaaggag tatggttgct ggaaatgggt gaaatgatgg ctactaaaaa agcagatatt
    28261 gaagcagtta agcattttct aagcaaatca gaggatatat atagggtcgc atatgggaag
    28321 agaacctcaa gatttttacg tcaatgtgta gttataggaa caactaatga taaagaattt
    28381 ttaagagata agactggaaa tagaaggttt tggccaatag atacaggagt aaagaagatt
    28441 aacaagagta tatttaatgg ccaacttgat aatgaaagaa atcaaatttg ggcagaagca
    28501 gtagaattat ataaagccaa tgaacagcta tatctatcag atgaggagaa aaaagaagct
    28561 gaaagacaac aaagaactca ctcagaagaa aatgctaaat ctggaattat cgaagagtat
    28621 ctaaataaac ctattactaa gaattggtat gatttaagta tttcagaaaa gagagaatat
    28681 attcatggtt cagattttgg tgatttaaaa gaagggacaa tattaagaga aaaaacgtgt
    28741 gttatggaga tatgggttga gctatttaat ggagaaccta aacaactcac acctatctta
    28801 tcaagagaaa ttaatgacat attaaaaggt ttagatggat gggagccaca cagtagtcat
    28861 ctaagatttg gaaaagtgta tggtaaacaa agagcatata ttagaacaaa atagtgtcta
    28921 caaagtaagt tttactaaat ttatgtaaaa taggtaggtg tctacaatgt ctacagaaaa
    28981 aatggctttg tagacacttc tgtagacacc taaaatatag atattgcaat gtatggaata
    29041 ctaacgtcta caatgtctac aaaaattata tataaagtaa taaaagtaat attaggcata
    29101 tatgtatata tatatgtatg cctaatatgc atatatacat atatatagaa aatctgtaga
    29161 cattgtagac acctaaattt aaggaagtga tattttgtta gaatcaaaaa tagaaaaaag
    29221 acttaaaaaa gagattgagt tgttaggtgg aaaggctatg aaatttattt caccagggga
    29281 ggcaggtgtg ccagatagga ttgtcttatt accagaagga catgttatat ttgtagaact
    29341 taaagcacca ggtaaaaaac caaggaagct tcaacaatat aaaatgcgag aattaagaga
    29401 attaggattt aaagttaagt gtgtaagcac attaaaagag atagatgatt ttatcaagga
    29461 ggttaaggga tggaatttaa accacatcca taccaagaat acataattag aaaaactata
    29521 gataataata atataggttt actattagat atgggattag gtaaaacagt ctgtactcta
    29581 acagctataa gtgaattaat gtatgattgc tttgatatat caaaagtttt agttatagca
    29641 cctttaagag ttgcaagaga tacctggagt agtgaagtaa aaaaatggga acatctaaag
    29701 catctaaaag tatctaaagt tcttggtagt aaattagata gagtgagagc tttaagtaca
    29761 gactcagata tttatataat aaatagagaa atggtaccct ggatagtgga tttttataaa
    29821 agaaaatggc catttgatat ggttgtgata gatgaactta gttcttttaa atcaaataaa
    29881 gcacaacgat ttaaaagttt aaagaaagta ttgcctttaa ctaaaagagt agttgggctt
    29941 actggtacac caacaccaaa tagtttaata gacttatggg cacagatgta cttacttgat
    30001 agaggtgaaa gactaggtaa aactattaca ggatataaag aacgatactt tgagccagga
    30061 caaaaaaatt atcaaacagg agctatatat aattggcagc ctaaagatgg agcagaaaat
    30121 gcaatacata ataaaataaa agatatttgt ataagcttaa aagcagaaga ttatttgaat
    30181 atgcctagaa aaatagataa taaaattgaa atacaccttg atagtaaaat acttaaatat
    30241 tacaaagaat tagaaaaaga gaagatatta gaattagaaa aagatataat aacagcttca
    30301 tcagcagctg tagcagcaaa taaactttta caattagcta atggagcaat ttatgataat
    30361 gataaaaatg taaaggaact ccatagagaa aaattagaag ctttaaaaga aattatagat
    30421 atttcaaatg gtaagcctat tatagttttt tataactata aacatgatta taatcgttta
    30481 atgaaagagt ttaagagttt gaaaccaaga acaatagaaa actcaaaaga tatatatgat
    30541 tggaataatg gaagaataca attattactt tgtcatccag caagtacagg acatggactt
    30601 aatttacaat caggtggaag tataattgtt tggtttggat taacttggag cttagaactg
    30661 tatcaacaag ccaatgcaag gctttataga caggggcaaa gggaaactgt tattatccat
    30721 catctaatct gtaaaggtac aatagatgaa caagtaatgg aggctctaga gaataaagat
    30781 aaaggacaaa gtgcattact tgaagcagtc aaagcaaaat taaaagaata tagggagtga
    30841 aagtatgaaa gtaaaaagaa aagatggaac ttataagccc aggtaaaata gtaagatgtg
    30901 cttggtgtgg tagaagattt tataagttgg ataaatctaa agttaagtat tgcagtagaa
    30961 gttgttcgaa gagagcaaga aggagtgatt taagtggata aagaaagtat aaaagaaatt
    31021 gtaagagagt taagaaaaga agaaagagaa gataggaaaa aaggcgtttt atataatact
    31081 agattattga tgaagcatta taatgatttt aagagacata tagactcagc ggtaagtgaa
    31141 gctaaagatg tagattactt agaggatgat ttaggtaagc ttgataatga agagttgtat
    31201 attttaagta taaagaaaag taaagcaaga actattatta tgatagcaca tatagattca
    31261 gcaatgaaaa ctttgaaatt aagacaagag cgtttacatt cttatgaaaa gtatagagct
    31321 ttagagcttt actattgtga tgaaaaaaca tatgaagaaa tagcagagat attaaattgt
    31381 ggagtagtta catcaagacg ttggattaat gaaatgataa aggaactggg agtgtattta
    31441 ttcggtatag atggcttgaa attaactgtt tgataaatat atgataaaaa gatgatattt
    31501 taatgatatt ttaaccctgt tataatggta gtatgaaaca agtgtataat atattccccc
    31561 ttgaaaaagg ctaagttacc ccaacttagt cttttttatt ttgtaaataa ggagaatgat
    31621 aaatgagtaa ttcatgactt agagtgattt ctaggtcttt ttttatacaa ttttaatccc
    31681 tcatattgaa gggtcgaaaa taagggtgtt caaattgaat attctttatt aataactaat
    31741 ttaggaggta gtagtatgtt gaaaatttta caagagaaaa atgtaaggat gatatggtca
    31801 aaaaatggag aagaagtttg atttaatgca aatgacgtag gagaggaact aggcatagta
    31861 aatattcgtg atacattaag aaatatagat agagaatata aaaagaaatt aatgagtcta
    31921 ctgtcggaga ttcctacact agaaacttta aagacaaatt gcctaacttt ggtactactt
    31981 ttgttacaga agaagctgtg tacaatatgt catttagaag taataaagca gaagcaaaac
    32041 tatttacgaa gtgggttaca aaagcactta aacaaattag aatacatggt tactatattg
    32101 ccacagaaaa agatcaagaa tggctggata taagaacaga aggtaaaaag gtcagaaaag
    32161 attttacaga tgaaatacaa gagtttgttt attaatacaa gcacttgaaa gagttatatc
    32221 tatgaaatca cctaggttga tagataaaag tatgaattat aaagaggtat ataaaagatt
    32281 aaagaattaa tagaaatgat ttaaatgact gtattaatag agggtctttt ttttatgtaa
    32341 tgaattaaaa atgaaatata tttgtacatt atagacagga ataaggtaaa agtattattt
    32401 agacttattt tgtggttgtc gaatgattat tgaaggatat tgactgatta tatagaatta
    32461 tatcattata aatatttgtg aaaggaataa tggtataatg agtaatttta aaaaaagata
    32521 tattgatgtt tatagaatag atattataaa taaaattaat gggagtgtct attcagatga
    32581 agaaatttta aaagaggtaa taaagacctt ctttaaggat aaagaatatt gtaaagaaaa
    32641 caaaaatgga attaatatta ctaaagataa aaagttttgg attacagaag taaaatgtag
    32701 cgaggatgat ttaataatca aggtgaaact tgaatatact aaatacaatc agaatacaaa
    32761 tattataaat gctcatacta aagaagtaga gggtaataaa aaaatggatc aaggagatag
    32821 caataagcag cacctattta ttaaatttat gaaggaaaat aatatagcag tagtattatt
    32881 tgaaagagtt tttgtggggg ttcccatgat tgaactaagt aaaaacttac atctatatta
    32941 tgaggatatg attgaaaata ataaatttga taataatatg tcaaaaacat caattaatat
    33001 tacacaaata gcaagtaaag attttataga acaaatatta gatttagatg gtgtttcaaa
    33061 aataacttta aatgttgata gagagaagtt tggaactgat gaagataatt tgttttctaa
    33121 tttaaataat tcaagacgac ataacgattt gatatataag cccacattta gaactagata
    33181 tttacctagt gaagttaaaa gatgttgcga aaaatatatt aaaggagagg aatttagaaa
    33241 taaaaaaata aataggataa taattgaggg agagaaaaac aagagaaaat taaagttgga
    33301 tactgagggt ataaagttgt gtagagaaat agaggtttct cttgatatag ataatcatat
    33361 agatagtgaa gacatttttg ataagatgaa taatttgata gatgatttaa ttgagaataa
    33421 ttcagttttt tttaatttaa tgtatcaaga agttgctatg agtgaagcat agattgcgaa
    33481 ggaggtgtta aaatgtataa aaaggtatta aatatcttac tcaattatta caaggctata
    33541 aattctaaag aagtagtaga gttagtttta acaccagtat taatatgtat tatttcatac
    33601 atgtttttta attcgtcaat taataaagaa gttgtaattt ctttaaacaa agatgtacta
    33661 actttgtcag gactattagt agcttttgga gtttgcatta ttacattatt gtttactaca
    33721 tataacaaat caatatcaga agcaaaagat ataaaaacag aaagaaaggt aaatggattt
    33781 aatatatcat actttcaatt catacagtta aaagcatatt atactgtaat aatggagatt
    33841 ttggttgttg taatatgttt tatcaataca ataatgctta ctcgatatta ttctaatata
    33901 attttctatg ttttaatatt ttttacagtt catataattt tatctctaac tacattaata
    33961 ataagtatgt ttcatttatc ctggaaggat agaggagact agatttgaaa caatcctatt
    34021 aaataggatt gtttttttta ttcccaaaac aaacaaataa agaggtggtg atgtgcaaga
    34081 tgtcaaagaa aaggtaaaac aagattactt aaaaggaatg aaacaaaagg aaatatcatc
    34141 aaagtatgac attagcttaa acactttaaa gtcatggata aaaagataca actgggctag
    34201 tgaaaaaaag aagggtgcac ctataaataa aagaggtgca cccttttcta ataaaaattc
    34261 agttggtcat ggtgctccaa aagagaataa gaacgctgaa aagtttggtt tcttctcaaa
    34321 atatctaccc gaagaaacta gggaattgat acaagaaata tctataaaag ataaatttga
    34381 tattctttgg gaacagataa caattcaata cgcagcaata ataagagcac agaagataat
    34441 gtatgttaaa ggcaaggaag aaatggttaa agaattaaag aaatatgaaa gcacagaaaa
    34501 tggtgagaag atagagtatg aatttcaatt tgcatgggat aggcaagcat cttttcttaa
    34561 tgcacagagt agagctatga gtgaacttag aagtttaatt aaacagtatg atgaaatgat
    34621 tcataaggat tggaatttgg ctacagagga gcagaaaaca agagttgaga agttgaaatg
    34681 tgaagttgat aacctaagta aagatgatat tggagatgat gagttgaaaa taagtgtaga
    34741 ttatggtgat agaaatgata gttagagtaa attttaatcc agatttcaag gaagctaatt
    34801 ttactaaaaa aagatacaga gcaatgaaag gttcagcagg gagtggaaaa tctgttaatg
    34861 tagcacaaga ctatatacta aagttaggag ataagaagta tcaaggagct aatctattag
    34921 tagttagaaa gtcagaagct acacataagt attcaacgta tgcagagctt acaggagcta
    34981 taaatcgtat ttatggtaaa caagctgata agtattggaa aactacttta aatcctttag
    35041 aaattaagag taaagttact ggtaactcta taattttcag aggagttaat gatgcaaaac
    35101 aaagagaaaa attaaaatca attaacttct cgaaaggaaa attaacatgg gtttggtgtg
    35161 aagaagctac agaacttatg gaaagtgaca tagacatact agatgaccgt ttaagaggta
    35221 ttttaactaa tcctaaccta tactatcaaa tgacatttac atttaatcca gtctcagcta
    35281 ctcattggat aaaaagaaag tattttgact ataaaaatga tgatatattt actcatcata
    35341 gtacttatct acaaaataga ttcatagatg aggcttacta cagaagaatg caaatgagaa
    35401 aagagcaaga cccagaaggg tacaaagtct atggtcttgg agaatgggga gaaactggtg
    35461 gagcaatact taaaaattat gttatacatg aatttcctac agaatttgag tattttgaca
    35521 atatgaggtt atcacaagac tttggattta accatgcaaa tgtagtactt agaattggct
    35581 ttaaggatgg agaattatat atatgtaatg aaatatatgt acatgaaatg gatacttcag
    35641 aaatcataaa gattgcaaat agtagaggtt tagaaaagac tctatttatg tactgtgata
    35701 gtgctgaacc agatagaatt aagatgtgga agagtgcagg atataaagct aaaggagtta
    35761 aaaaaggacc aggaagtgtt aaagctcaaa tagattattt gaaacaatta agaatacatg
    35821 tacatcctag ctgcactaat accataaaag aaatacaaca atggaaatgg aaacaagatg
    35881 aaagaactgg attatatctt gatgaaccag ttgagtttat ggatgatgca atggctgcgc
    35941 ttagatattc tatagataat aagcttaaaa ataatggaat aagcttctta aagtaaagga
    36001 ggtgttaaat atttatataa gtgaaacaga tttaataaaa gttcagttaa aaaaagagag
    36061 cacctttaac ctagtaaaag tcatagaaca ctacatctta aagcataggc cagaaaaata
    36121 taaacaagga gaagaatact attatggtaa tactgatgta aacaataaga gaagatatta
    36181 tctcttagat ggagctaagg ttgatgattt tactaaggtt aataataaag caattaacaa
    36241 ctaccataag cttttagttg accaaaaagt gggctatagt gttggaaatc caatcgtatt
    36301 taatgcagat gatgataatc tcactaagct tttaaatgac ttactaggag aagagtttga
    36361 cgatacaata acagaactat atctcaatgc tagtaataaa ggggttgaat ggttacatcc
    36421 atatattaat agaaaaggtg agtttaaata tgtaataatt ccagctgaag aagcaattcc
    36481 tatttgggat agtaaaagac agagggaatt agttgcattt attaggtttt attatattga
    36541 agatatagat ggaaataaaa taaaaagagt tgagtactac acagaaaatg atgtaactta
    36601 ctttgttgaa agaggtaata gttttgttca agaattttta tatgatgaat atggaaaaat
    36661 gactgatata caagaaggtc attttagaat aaataacaaa gaacagggtt ggggtaaagt
    36721 tccatttata ccttttaaaa ataatgaaaa gtgtgtctca gatttaactt tctataaatc
    36781 attaatagat atatatgaca ataatatttc tacactagca gataacttag atgaaataca
    36841 agaggttatt tatgtattaa aagaatatcc aggaacaagt ctacaagagt ttatagataa
    36901 tataagatac tataaatcaa ttaaagtaga tggtggaggt ggagttgata aactagagat
    36961 aaatatacca gttgaagcta aaaaggagct tcttgataga ttggaaaaga atataattat
    37021 ctttggtcaa ggagttaatc cagaatctca aaacacaggt gacaaatcgg gtgtagcact
    37081 taaattttta tattcactac ttgacttaaa atgttctaag actgaaaaga agtttaaaaa
    37141 agcaattaga gagcttttat ggtttgtgtg tgagtattta aagataagtg gtagtaagag
    37201 ctatgattat aaaacagttc aaattacttt taatcactct atgataataa atgaagctga
    37261 aaagatagat atggcagcta aatcaactgg aattgtatca gatgaaacta ttgtttctaa
    37321 ccatccttgg gtcgaggatg ttaatgacga acttgagaga cttaaaaaac aggaagatac
    37381 tcaaaaagag tatgatgatt taattcctaa taatcaagat ggtgttatag atgaaacata
    37441 aagattattg gaggaagaga tttgaacaat tagaagaagc tcagaataat aaaagtataa
    37501 aatattatct tgaattagaa aaacaatata aactagcaat gtctaatata gaaagagata
    37561 tacttatatg gtataacaga ttcactgaaa atgagggaat atctttattg gaagctaaga
    37621 aactgctaaa tacaagagaa ctagaagagt ttaaatggag tgtagaagaa tatattaaat
    37681 atggtaaaga aaatgctata aatcaaaagt ggatgaaaga gttagaaaat gctagtgcaa
    37741 gagttcatat aacaaggctt gaagctttaa aactgcaaat acagcaacaa gtagaagttt
    37801 tatatggaaa tgaacttgat ggtattgata aactaatgag agatatttat acaagtggat
    37861 actatcatac agcttttaat gttcaacaag gagtaaacgt tggttggagt ttaatgagtc
    37921 ttgatactaa cagaataaat aaagttattt ctaagccttg gactagtgat ggattaaact
    37981 tcagtgaaag gatttggggt aagcatagac ctgctttagt aaatgaatta catactaagc
    38041 taactcaatc aattattaga ggtgaaaatc caaagaagct agtaaatgac tttgctaaga
    38101 gatttaaggt atctaagtca caagctaaga acttaataat gactgaatca gctttctttg
    38161 catcagcttc aagaaaagat tgttttaatg atttagatgt agagaaatat gagattattg
    38221 ctacattaga tttaagaact tcaaatatat gcagagagtt agatggaaaa atatttgata
    38281 tgaaagatta tcaagttgga ataacagctc caccatttca ttgtcgttgt aggacaacaa
    38341 cagctccttg gttcgaggat gaagaaggct atagagcagc aagaggagaa gatggaaaaa
    38401 catattatgt accatctagt atgaagtata atgagtggta tgagaagtat gttaaaaata
    38461 atagtaaaca aactggtgca aaatatacta aaggtgatat cgagtggaat ataagaagag
    38521 aagaagaagc agaactatat tacgataata ttagaaatag aaaagatgat atttccaaaa
    38581 tatcaaagaa tacaaattgg tcagaaaaaa gtataggtca aattaaaaat catattttct
    38641 acaatactca tataatgaga gatggaacta gacgtatgtt ggattctgac tatagtatgt
    38701 cagttgcttg gcaaagactt ataaatggta catacgaaga tattgatatt ctcttattaa
    38761 aacatgaata ccttgaaagt atatttgaga aaaagtataa tataagtaac ttagaagccc
    38821 atagaatgac tgagaaaaag catgattggt ataaagaatt aattaaacag aaaggagagt
    38881 ttgaagaaga tgattgtctt aatgaactta ttagaaaaga ataatgaata tgttatatat
    38941 agttatggat atgaagaaaa taagcttgat ggaagaataa aaatatattt agatgatttt
    39001 tataattatg aaataataaa agagtcaaaa gatgaacata taagtaaatc agcaacgtta
    39061 aaagctattt ctaaacttat aaaagctgct aaaaataacg atttgaaaaa agaaatgagt
    39121 tatcaatgtt agaagcactt actgaacaat aaattagtag gtgcttttat tatgtaaaag
    39181 tttaaaaaag taggtaattt taatgtaaat attaactcaa gttatagctg tagtttgtgt
    39241 agtacaaatc tttattaatt gtattgctaa tgtcaatgta tgtattcttt gcaataaatt
    39301 aaaagaaaaa atgaagctaa tatagataaa gtttctgatg aaattctaaa gagagtagga
    39361 gaagaattaa ataaatcatt agacaaaagt ctttaaagac tttttttatt gtgtaaaaaa
    39421 tgaaaggaga tatttaaaag atggattggt taaaagaatt gctagaagga ataaaaatag
    39481 aaaataacaa aattgatgta gtttctcttc aaaaatctat agaaaagaaa ataaaagaga
    39541 ctacaattac taaagaagat tatacaaatc ttgaaacaca acttaataca gctaatgaaa
    39601 ctattaaaaa gtttgaagga ggtatgacaa aagaagatgt agagaatcta aaaacaactt
    39661 atgaaactga taagaaaact ttggaagaaa cctacaaaaa agaaattgaa gaaaaagatt
    39721 ttaattactg gttaggtgat gcttttaaat ctgttaaatg tagagatgaa atagcattaa
    39781 aagctcattt agatatagaa gcactaagaa atagtaaaga cagacaaaaa gcttttgaag
    39841 agcaaataaa tcctttgaaa caggataaag attatttgtt taatgcaaca ctagaaggtg
    39901 aagaacctaa aatagatact ataacaccag ggcaagagcc taagataaat gattttggtt
    39961 ttaattttac tggggtaaga cctcatgaaa ataataataa ataggaggaa ataaaatggc
    40021 agcactaaat tatgcaaaag aatattcaaa tgttttagca caagcatatc cttatacttt
    40081 aaacttcggg gatttgtatg caacaccaaa taatggaaga tatagatgga ctggttctaa
    40141 aacaatagaa ataccaacta tatctacaac tggaagagta gattcaaaca gagatacaat
    40201 agcagtagct caaagaaact atgataatgc ttgggaacct aaggtattaa ctaatcaaag
    40261 gaaatggtca acattggttc atccagcaga tataaaccaa actaattatg tggcttcaat
    40321 aggcaatata acaaaagtat ataatgagga acaaaagttt ccagagatgg atgcttattg
    40381 tatatctaaa atatatgctg attggaccgc attaggtaac acagcagata caactgttct
    40441 tacaacagca aacgtattag aagtatttga taagttaatg gaaaaaatga cagaagctag
    40501 agtacctgaa aatggaagaa tattgtatgt tactccagta gtaaatacac ttatcaaaaa
    40561 tgcaaaagag atacaaagaa cagtaaacat aaaagatggt ggaacttctt taaatagaca
    40621 aaccacagat attgacacag ttaaaataat taaagtacca tctaatctaa tgaaaactgc
    40681 atatgatttt acaactggat ggaaagtagg agcaggagct aaacaaatat ttatgtcctt
    40741 agttcaccca agtgcaataa ttacacctgt ttcttatcag ttctctaagt tagacgaacc
    40801 aacagcagtt acagagggaa aatacttcta ctttgaagaa agttttgagg atgtatttat
    40861 attaaataaa aaagctgatg caatacaatt tgttgttgaa ggagctggag tataatggca
    40921 caagtaagga aattaaatag aatattaact atagaagagt gtaaaataga tgatttctta
    40981 gagatgggat atgatttgat agatgaaact ggtaaggcag taaagtatgg caagtcatta
    41041 aatgtaaaag atttaatagc tgaaaataat attttaaggt caaaagttga gtctttagaa
    41101 gaagaaaata agcagcttaa agagaaaaat aagcttacta aaaagtaggt gaaaattatg
    41161 gaaaataatc tgattgatga aatagaaaaa agacttgaaa gttttggata tatattaaaa
    41221 gatggagata agtggttaat agattttata agagaaaaaa tagaaaatat tattaaacta
    41281 gattgtaata taaaaactat gccaattgaa ttgaaagaaa ttgaagttga tatgatagtt
    41341 ggagagttct tatttactaa gaaaaatatg gggcaattag atatagaaag cattaacttt
    41401 gaagctgtag aaaagtctat atcagaaggt gatacaaagg tagattttgc tataggaagt
    41461 ggctctcaaa caccagaaca acgctttgat agcttaatag cttatcttac tacttatggc
    41521 aagaataaga tattaacctt taggtgctta agatggtaag taaaactaga aaagcaatag
    41581 aaatgttata tagagataaa tgtactatag ttgagtatca gccaatcaaa gaccctgtaa
    41641 caaaacgaac taacaataaa gaagtgattg tattagaaaa tcaaccatgt aaactttcat
    41701 ataaaaatat agtttctgct acagaaggga aagtagctaa gctagagcaa actattaaac
    41761 tctttatatc tccagatata agcgttaaag caggttcaaa acttattata actaatcaaa
    41821 ataatattac aaaagaatat ataagaagtg gagaatctgc tatataccca aatcatcaag
    41881 aaattgtatt agaattacta gaggataaag cgtaatgggt agaggtggaa gtgttaattt
    41941 taaagaattg aaaaagttgc aaagaaatct acaaaggttg gaagaaagtc aactcgataa
    42001 gttttgcaga gattgtgcaa aagaattagc agcaagatta attggcaaag ctataaaacg
    42061 tacaccagtt gatacaggag tgttacgaca aggttggaat ggtgtggctt atgcaagggc
    42121 acttccagta attaaagctg gagatactta cattatagaa attattaacc ccatcaaata
    42181 tgccagtttt attgaatatg gtcatagaac tagaaatcat aaaggttggg ttaaaggtag
    42241 atatatgatg actatttcag tgcaagaatt aagaggtcaa gtagatgtaa taatagaaaa
    42301 gaaattaata aatttattaa agaaggtatt tgatgcttaa taatattata gatggaatat
    42361 cagtaaaatt agataaatca tttggagaga gttatacaat ttatagtgaa gatgtggagc
    42421 aaggtataaa tgaaccttgt ttttttattg ttcctttaaa tccaagcaaa gtatcatatc
    42481 caagtggcag gacattaaaa aagaactctt ttgatgtaca ttattttccc aaaagtaatg
    42541 ataaatcatt tgaaataaat gaggtagctg agatgctact ggaggaatta gagtatatag
    42601 aaattgatgg agatttagtc agaggtacaa atatgaactt tgaaattgta gataatgttc
    42661 ttcatttctt tgttgattat aactatttca ctataaaaag caataataca gataagatgg
    42721 acacagtaga gttgtttggt ggtctaaaga gaggtgataa acttgagtaa aacattaagt
    42781 aaagaagaaa attataagtt tactaaggag caaatagtta attctaaaag gtatgtaaat
    42841 agaaaagatt tattaaatgc aatcttaaag gaagatgaat tgtattcttt ctcagaagtg
    42901 gaagatatga taaataattt tatgaaagga gtgagctaga tggctttagg tggaggaaca
    42961 tttgtaacac aaaataaggt cctacctggt gcatatataa attttatctc agctaagagg
    43021 gcaaccagtt cattatcgga tagaggtatt gttgcaatac ctttagagtt agattggggc
    43081 atagatgaag aagtattcca agtaaccagt gatgattttg agaagtattc agtgaagtat
    43141 tttggatatg attatactca tgagaagctg aaaggtttga gagatttatt caaaaatata
    43201 aggttgggat atttttataa aataaataaa ggagttaaag ctagttgcag tattgctaca
    43261 gctaagtact caggtactag aggtaatgat ttaaaagtta tagtaacaac aaatatagat
    43321 gataacacta agtttgatgt tgtaacactt ttagataata agaaggtaga tattcaagca
    43381 gctaaagtca ttacagactt acaagataat gactatatca cttggaagaa ggatgcaaca
    43441 ctagaagcaa gcgcaggact tgtatttact ggtggaacta atggcgaagc tgtgacagga
    43501 gcagagtacc aaactttctt ggataaaata gaaagctata gctttaatgc tttaggatgt
    43561 ttggctataa caacagaaat taaaagttta tttgtagaat ttacaaagag aatgagagat
    43621 aaggtaggag ctaagtttca aacagtacta tataagaaaa gtgatgcaga ttatgaaggt
    43681 gtagtgtctg tagaaaacaa gattaaagat attggattag tagaatctag cttgatttat
    43741 tgggtaactg gagctatagc tggatgtgac ataaataaat ctaatactaa taaaaagtat
    43801 gatggcgagt ttgatattga tgttaactat actcaaatac aacttgaaga agctttaaaa
    43861 actggtaaat ttatattcca caaggtggga gatgaagttc atatgttaga ggatataaat
    43921 acttttgtat catttacaga tgataaaaat gacgattttt caagtaacca aagtgttaga
    43981 gtacttgacc aaattgctaa tgatattgca actttattta atgaaaagta tttaggtaaa
    44041 gttccgaatg ataaggcagg aagaataagt ttctggaatg atgttgttaa acaccataaa
    44101 gaattagaga atataagggc aatagaagat tttaaaactg atgatgttag tgtagagctt
    44161 ggaaatgata agaaaactgt catagtatct gatgctgtta aggttataaa tgctatgagt
    44221 aagctttata tgactgtttc agttagttaa gagaggagtg tgataatatg tttcagcaaa
    44281 taaaagcaag agatacaata agtgcatcta aggcagaatg ctatgttact atcgagggta
    44341 aaagatataa ttttatgcaa gctattaact tagaagctaa gatggaaaaa aataaaagtg
    44401 aagttcctat cttaggtagc actacaaaag ggaataaaag tactggaagc aaatacacag
    44461 gaagtgcaac atttcactac aatacttcta tatttagaga gcttctttat aggtacaaag
    44521 agactggtga agatatttat tttgatatac aggtaacaaa tgaagaccca acgagttcag
    44581 ctggacgtca aactataata cttaaggatt gcaacatgga cagtggaatt atagttaaat
    44641 ttgatgcaga tggtgagtat cttgatgaag atatggactt tacatgcgag gattgggaat
    44701 tggttgaaaa gttcaatata ataaatggaa tggaataaaa cacacattta taaattatag
    44761 atgtgttttt ttatataaaa aattaaaata aaaggagatt aggataatat gagtaattta
    44821 agtgcttttt taagtcaaaa tgcaataaag gttgataatg taaaatatat agcaagtgat
    44881 agatttttag acgaagaagg aaagccagtt gaatgggaat taaaagtttt atcttctgag
    44941 gaagatgaag tattaagaag aaattgtacc aaaagagtaa aagtgattgg caataacggg
    45001 aagccaacag gtcaattcac aagtgaaatt gattataaca gttatgtagc tgaattatgt
    45061 gtagcatcta cagtatttcc agatttaaag gatgccgaac tccaaaatag ttatggagtg
    45121 atgggagaag ctcagttatt aaagacaatg cttacagcag gtgagtatgt caactataca
    45181 gtaaaagtta atgaggttaa tggatttgat ataacatttg aagataaagt agaagaagca
    45241 aaaaactaat taggggcggc gattttgatg ctagtatcac gcattattgt atccaaaaat
    45301 taaagtggaa accaggtgat tatatgggat tagagattaa tgagagagca ttagcagccg
    45361 cctcaatact tattaagata gaggatgaag aggaagcaat gaaagaagct gaaagagaga
    45421 gaaagagggg tagaagaaga tagcaaaata aaaaaataaa tatagaatag gtaaaatatg
    45481 taataattat atgttataat atttttagca agaagatgta atctacaatt tatagagtgg
    45541 agttcataca aaagattatc ctcccaacgt atagaaggga ggtgaatatg tatggataat
    45601 tttttgattg gtgtattagc tagtttaaca gctagtctaa tcggttacat agtttgtcta
    45661 tgtatcaaaa aagtaaaaag ccactctgtg caagagagtg acttagatgt tgagcttaaa
    45721 ttttcattta agttcaaaaa aaataaacat taaattgttt agaacttcac tctacttcca
    45781 aatagattgt agttcttctt gtttttatta taccacaaat tggtacagat attcaaaaat
    45841 aatattttta tgatataata aaaatgtaga gattttgcag tgttcgattt ttgtaataaa
    45901 atatggctta acaattggaa tacaaggcat tgagggtgtg tgataaatgt tatcaattgc
    45961 actactcatg gctcactgca aatttgagag aggtatgtat gtgtaggtat tggaaatgcc
    46021 aagtttattt tggggtttta gattaactat atggaatgta aatataatta aatcaaatac
    46081 tccatttaaa atagatgcta gttttagatt aactatatgg aatgtaaatt ttagttccaa
    46141 gtgcatttcc tttttgaaat tctggtttta gattaactat atggaatgta aatcagcttt
    46201 acatatctat ctatgatttt tgaatctcca tgttttagat taactatatg gaatgtaaat
    46261 tctaatttag ttgttaaaat aaattcctta ccaattgttt tagattaact atatggaatg
    46321 taaattgagc tgttagataa tatcctagca tttttatttt tcgttttaga ttaactatat
    46381 ggaatgtaaa ttatgtacct agaaatttag aaagttttgg agaaatagtt ttagattaac
    46441 tatatggaat gtaaatttcg caacttatga tggtgaaatg attacattaa caggttttat
    46501 attaactatg tggtatgtaa agattactct aaaagtcttt ttatcatttt ctacctcaat
    46561 tttatattaa ctatgtggta tgtaaataaa gcaaaagata ggaatgataa ttttaaaact
    46621 ccaaactttt atattaacaa tgtggagaaa aactaaatag aagaaagaag cacttatttt
    46681 tggtaggtgc ttttattttg ctcaaaatat tttaaaacaa tagactaagt tcttattttt
    46741 agatagaatt atatttgaat aaagaattta ataggggaga gttcattatg tggggaaaat
    46801 ttaaaaaatt aagtttgttg aagaaaattt tagtgatatt tttaatatac tttgttgtat
    46861 ttacagtatc aatgatgatt catcaagcga tacgagattc aaaaaataga gatgaagtaa
    46921 atgaaggaaa tattacaaaa gaaaatataa ttagcgaaag agaaaaagaa gatatttata
    46981 aacaagagat gcaagcaaaa gtagacttta tgataccaga agacttaaaa gataaaacaa
    47041 catattatgt taacatatta aacccaacaa aaggtgaggg atatatagtt agtattcaag
    47101 tggaaaattc taggtttaat gatgaaaatg agtgtagaaa ctttactaaa gaatttgtaa
    47161 acaatataaa agatatgaat gatatccatt cagtgagaat aagctttatt gttgatgtga
    47221 cactcactta taatgtattt ttagatgatt ggaataatat aaaaaataat gtaaatttaa
    47281 ttgatgattt ggatttctcg tctggaaatt aggtgaatac tttattttaa aattaaatct
    47341 gttatataga aagcacttac tttttggtag gtgcttttgt tttgctcaaa attggtcggt
    47401 tgagtaaaat aattagaaaa aattagtaaa aactcttgaa aagtgtcgcg atacaatgta
    47461 taattatatt atcgcgatac agaaaagagg tgaaaattat tactgatagc agtagagcag
    47521 attacttcaa gcagagacga cagaataaga aaacttttag tgttctacta gatagagaga
    47581 aagtagaaaa aattgaagaa catttaaaaa agcagaacaa gactaaaact atttggcttg
    47641 aagaaaagat taatgaagag ttagaaaaag aggaataaaa aataagagac gttctccccg
    47701 accaaagatt gaacatccct tattgacgta tattatatac actaactata gtatacgtca
    47761 ttccttaaaa aaattcaatt aaggagtgta atattatgaa aaatgaatta atgatgtttg
    47821 aagaaaagaa agttgaagta cttgaatata atgggcaagt tttatttaat ccatatgatt
    47881 gtggaagatg tttagagtta agtgatagtg caataagaaa tcatttatct aaaatgaatg
    47941 atactcaagc tgtattatta aaaaattcta atgtcctaga taaggacttt agaaaattgc
    48001 ataacacagg tgaaaagttc ttaacagaga gtggagtata taagttaata tttaaatcta
    48061 aaaaagaaga agctgagaga tttcaagatt ggataagtga tgaagtactt ccagccattc
    48121 gacaaactgg tgcatacata acaaataacg ctgaccctca agcattaaga gaaaaagcaa
    48181 atgaaataga aagtttagat acagttaaca agactataga aatattaaca ccattcttag
    48241 atggtgctgg aatagatgaa aaagcaaagt tacttacagc gaagactatc tataaaaagg
    48301 caggaattga gttacctctt gaaatagaag agaaggaaca cttctttgac actgtacaaa
    48361 tagcaactaa gttaaatatt tattctaagt ctaataaacc tgcatttcat gcaataggtg
    48421 aaattattaa gaagttagat atacaagata atgaaaagtt agtagtacta gagagtaaaa
    48481 gaggttggag tggaagtgtt aataagtatt cacagagtgt aatagataaa gtgagaaatt
    48541 ggatagagga aaataataga cctagcaaga ttgcaggtga gaagaagaat tatcatgtgg
    48601 tttataagat tgagtaaatt tatcagttgt attaaataat ttagtttagt ttattttagt
    48661 tttgaggggg attaataaaa tgcgtgaaag tttacttaat gaatataatt taaaaactga
    48721 tgaagatgta gaatactttg taaagtttgc taatgcgtta tatgaactaa aacagaatag
    48781 tgaagaaaag tttcaagaat atgcagagat attaagaggt attcttagag aacaagaaga
    48841 gagaaaaaat tagagaaaaa taattaaata aatagataaa gcacttggat attatgttgt
    48901 ttcaagtgct ttatttggta taaaatggta taatggaagt agggatttat attaactaag
    48961 tggtatgtaa aggctggaat taatgcgact acagtagaag aaaagaaaat tttatattaa
    49021 ctaagtggta tgtaaaggca tttcggcata tgacaactgc tatgaatata gtacatttta
    49081 tattaactat gtggtatgta aatgttcatt tgtatttctt ccaattttct gttctatcct
    49141 agttttatat taactatgtg gtatgtaaat gataaatttt atagatttgt aagtttagtg
    49201 aaagaagaat gtaggaaaaa agaaaagaaa gagaataaat aatatagata aagcacttgg
    49261 atattgtata gtttcaagtg ctttgtctgt taaaaaatgg tataatagag ataagagtta
    49321 tattaactat gtggtatgta aaggtttgag aacgctgtat aaagcttgta gctagttctt
    49381 gttttatatt aactaagtgg tatgtaaagg ttgcatcatt aaatattttc cctacaaact
    49441 cttttcattt tatattaact atgtggtatg taaatagtac atacaaagag tctataaaat
    49501 tatctataaa gggttttata ttaactatgt ggacttaaaa ttaaaaataa ttcaaaaaca
    49561 cttacaaatg agtaagtgtt tttttaatga aaggaggtga taataatgta aaaattttac
    49621 taatatagta taatattgtt aaagaatata atttaggggg atattatatt atgaagaaaa
    49681 aagtatgttt tttattttct attcttatag ttatctgttt agctattgta ggatgttcta
    49741 attcagaaag tccagaggag agtagtaaaa ataatgaacc aaaaaaagaa gaaaaaaagg
    49801 ataaagaagt agtcatagga gagaaaatta tttcagataa aatggaaatc actattaata
    49861 atattgaatt ctcttatgat gttttaccaa aggttaagga aagtttatat acacattatc
    49921 ctgctgagtc aggcaaagta tatattgata ttgctgctga tataaaaaat actcaaaaac
    49981 aagagttaaa ttgttcagat ttactaacta ttgaagcaaa ttataatgat gggtataaat
    50041 attcatcaca aacaatagta gaagatgaaa ccacaggttt tacttatgat aatatttcta
    50101 gtattgaccc tttagaaaca aagggagtta gatttataat cgattgccct gatgaagtaa
    50161 aaacaagtga taagccagta atattaagtt ttacatttga tgggaataag tatgtttata
    50221 aaatgaagta atttatacaa aaatgaatat attataatac caaggagata ttttatggat
    50281 gatatagtag aatatatatt ttgtagcgag tgtggagcaa agtgtttaaa aggaagcaag
    50341 ttttgcagtg aatgtggaac ggaaatagct gatataaaaa tgttaaatga aagcattatt
    50401 aaagaaaagg aatatgattt gaagggtatt gatttacaac atgtaatgca agaaacaagt
    50461 tttataaaag cttcatctgt aagaagattg aaagaattaa ctggaataga gttggatgat
    50521 tgtagaaaaa tattagaaga accatatcaa aaatattata atgaaaatgc tgatatgctt
    50581 gaagaaaaaa gaaaaaaaga agatgatata tcaaaaatta gaaaagccaa agaggaaaag
    50641 aaagaaaaag aaaaaatagc ttgttgccct gcatgtggtt caacttcttt gacaacacat
    50701 aaaaaaggtt ttggcatagg aaaagctata acaggagcta ctatagcagg aggcattggt
    50761 ctcgtagcag gaaacatagg agcaaagaaa gttagagtta catgcttgaa ctgtgggaaa
    50821 cagttttggg caggcaaaaa atagatacta aaaataaaac acttactcag gtaggtgttt
    50881 ttttaatgaa agaaggtgat gataatgtaa aaattttact tatatagtat aataatctta
    50941 taaaattgcg tagggggtaa tattatggga ttatttggag gtaaagaacc atgttgcata
    51001 tgtggaggaa agggtaaaaa taaagtttta gaaaatgaat atctgtgcaa taattgcttt
    51061 gttgatttta cgatattctc tagtggaaga ttaaaaacaa ctagtgcaat gcaagtatta
    51121 gcagaccatg aaggaataag aaagtttata aatttttcta agaaaaatag agaactatta
    51181 gaaaaatttg ttgagacaaa taaaattaat aaattcatat caattgatga aaataataaa
    51241 tttattaaaa tatcagatat tcgtaaaggc ggagatataa tagaaaccgt atatgcaact
    51301 gatgaaatta tagagtttga acttttagaa gatgaagagt ctatagttag tggtggttta
    51361 ggaagagctg tagttggggg tgctttattt ggtgcaactg gagctgtagt tggaggtgta
    51421 acaggtaaaa aaacaacaag aaagattgtc aatacattta aaatcaaaat aacatttaat
    51481 aatattaata atcctttaga atatattaat ttgattaata caaggacaaa aactaattca
    51541 tctatatacc aaaatgcttg taatgaagca caagagattt tatcagtact ttcaataatt
    51601 gtaaaaaaca atgataaagc taacaatgaa caagataaaa ctagtagttc aatagagcaa
    51661 gtaaaaggat tgaaagagct actagatata ggagcaataa cagaagaaga atttaatact
    51721 aagaaaaaag aattattaaa tttataataa ctagacactt acaaaagtaa gtgttttttt
    51781 atatggaaat ttatgaaagg agagtgataa aatggcaact atacaaacat ctatccgaat
    51841 tttcgatgga atgacacctg catttaggag tatgacagca tctattaata cgacaattaa
    51901 tagtctagaa agactacaag ggagattgaa taatccgctc aatacaggtg gaatacagac
    51961 atctcatcag agtttaaata acatagaaaa tattttaaca agaatagaac aaaacatagg
    52021 aaaagcagat gaacaacaaa gaaagtttaa cgaggatatt aataaaggag caagtaatac
    52081 agatagatta ttaggaagtg ttaaaaaggt tgttgggact tatatgggat taaagacgat
    52141 aggaggatta gcaaatttaa gtgaccaaat gacgagtaca aatgcccgtt taaacatgat
    52201 aaatgatggt caactttctg acggaggatt gaataaaatg attttccagt cggctgaaag
    52261 gtcaagagca tcctatctag acacagcaca gatagtaagc cgtataggta tgaatgcagg
    52321 gagtgcattt agtagtacta gagaaatagt aagctttgca gagcagctca acaaaaaatt
    52381 tgtaatagca ggtgcaagta ctgaggaaat gaactcggca cttttacagt tgactcaagg
    52441 attaggaagt ggagttttgc gtggggaaga attaaatgct gtatttgagt cagcacctaa
    52501 tatcatcaaa agtattgcgg attatttaga tgtggacata ggaaagattc gaggaatggc
    52561 aagcgaggga atgttgacag cagatattgt aaaaaattct ctgcttgcag catcagcaga
    52621 aacaaatgct caatttgaaa aaatgccact tacaataggt caaatcttta catcaattaa
    52681 gaataacgca gtaatgatat ttggagcgat acaaaaaaag attgaggata cagtttcaag
    52741 cggaggattt cgaaccttca tagttaatgt aacagattcg ttgtatgtct tgggagctgt
    52801 tggatatagt gtctttaatg ggtttattga tttgctgagc agtccaacat ttcaaggttt
    52861 tgcaaatatg atgattgtcg gaatcagttt aattactcaa ggatttgggt ggctattaac
    52921 agtattagga agtgttatta attttatttc acaaggttgg agtataatac aacctatttt
    52981 gataacgagc atcgttttgt ggggcttata taaaacagct gtcatagcag gtgctttagt
    53041 tacagctatt caggtagtgt ggatagcttt acagacattt tggactaatt tgctaaatgg
    53101 ttcgttatta actaatataa tgatgaatat agctgcaaaa atatcaacag atgcactaag
    53161 tggttcaatg ttacttttaa ttaccacaat agttatggtt gtagcagcag tagccttagt
    53221 aatagcagca atatttgtag cagtagcaat atttaaccat tttgcaggaa caagcatttc
    53281 tgcaactgga gtagttgtag gagctttcta ttttctagga acttgcattt atgatgtatt
    53341 cgcaggagcg tggaacatag ttatggcatt tgcagagttc tttgttaatt catttaatat
    53401 cgttatctac aatgtgcagt tattatttta taaattccaa aactttgtaa taaatgccat
    53461 gggagatgta ggaggaagtt ttgacaattg tgctacagct ttagcaaatg cttttgtaag
    53521 tgctgctaat atagcaataa aaggtataaa tggagttata aaaacactaa atttgatacc
    53581 aggcgttaat ataaagacat ttggaagctt ggacaaaata gattcttttg taaaacaata
    53641 taaagattac caaaaaacgt taaaagagcc tgtaaagcct gctgaatgga aagctccaac
    53701 tatgaaattg aagaatcctg tagattcatt taaaaaaggg tatgaagtag gtcaaaattt
    53761 agaaaataaa ataaaagatg cttttgacat tagcaagata gcagaaaagg caaaaaaaga
    53821 tttaggacta gatgaccttt gggatgataa atatggatta ggagatagat ttggttcagc
    53881 aggtcttaat tcacctttaa atgacgcagc aaaaaatgta aaagacacag caggaaacac
    53941 agccaaaatg gctaaaacaa tggataaaag tcaagaagac cttaaatact taagagacat
    54001 tgcagaacaa gaaacaataa acagattcac aggagtaaac ataaaaattg atatgaacaa
    54061 tactaacaat ataagtaaag acacggatgt ggatggtata gtaaatgttt taacagaaaa
    54121 actgaatgat gctatgattg tatcagcaga aggaatagtt tagaaaggag ggatataaat
    54181 ggcttatgac ttttatttag atggagtaca attaccaata cctccgccaa agttagagat
    54241 taaagttaca aataaaaaca agacagttga tttgataaat actggagaag taaacatact
    54301 aaaaaaagaa ggattatctg aaataagttt tgaagcagaa tttacacata ataagttgcc
    54361 attctatcgt ggagctttta gtgatgttca attcttttta agtaagctag aattactaaa
    54421 aactgattgt aagccatttc aatttattgt ctcgagggaa atgggtggaa aagtactatt
    54481 taacactaat ataaaagtat ctcttgaaga gtatgctatt tcagaagacg cagataatgg
    54541 ttcagataca aaagttgcaa taaagttaaa gcaatataga gattactcaa ctaaaaagtt
    54601 agttcttgcc cctcctaaaa atgagactgg tagacctaat gtaaagatag agccaaaacg
    54661 agttgattca gtcaatgcca caaacactaa aacatataca gtaaaagcag gggatagcct
    54721 ttggtcaatt tgtcagaagc aacttggtaa tggttcgtta tacaagaaag tatatgagtt
    54781 aaataaaaca atgatggata aagctaacaa gggtaaaaaa gtacctaaat ataccatcta
    54841 taaagggcag gtgttgaggc ttgtctgatg atttagttct ggcgaatgat agagatataa
    54901 ggctagttat tgcacattgg gaagatttct acgaacctgc tgtcattgat ggtatcacat
    54961 gggagataga aagaagaggt tcaccttcaa agttagagtt tactatagca atggatgata
    55021 tattagagtt ttgcgaaggt aattctgtaa ggatatatta taagggaatt ggcatatttt
    55081 atggatatat atttcagaag aaaagagata aagaaaatca cattaaaata gttgcttatg
    55141 accagttgag atattttaaa aataaagata cttatgtata tagtaataaa acagcaagtg
    55201 aacttgtaaa gatgttggct aaagatttta atttaaaata caatgtcata gaagatacaa
    55261 aatataaaat atcgagagtt gaagaaaata aaacactctt tgatatggtc ttaactgcac
    55321 tagatgatac tctaagagag aaaaaagaaa tgtatgtgtt atatgatgat tttggaagaa
    55381 taacattaaa gaatgttgca tcaatgaaat tagatactgt tatgaacaat gatgtaatag
    55441 aagactttga ctataattca tcaatagata gtgatactta cacaaagatt aaacttgtga
    55501 gagataatga agaaacagga aaaagagatg tgtatattgc tcaagactca acgcatatga
    55561 ggagttgggg aatacttcaa atgtttgata cagtagacaa aaacatgagt gaagcagaga
    55621 taaaacaaaa gtgtgatata cttctaaaac tatataataa gaaaactaag tcattaagtt
    55681 taaaaaatgt acttggagat attagagtga gagcaggttg tttagtacct gtttttttaa
    55741 atctaggaga tattaaactt caaaattata tgctagttga gaaagtaaaa catacttttg
    55801 aaaataacag tcattttatg gatttgactc ttgttgatgg agatgaattt gcttcttatt
    55861 cttcaagctc atattcaagt ggaaatacta acaataagga tgaaaagaaa aatggtcctg
    55921 cacaaagtat tacgaaaaaa aatacaggta aaaaagttcc tgctatattt actgcatatt
    55981 atccagggaa caatgcaatg gaaggcggaa aaacagattg caatggaaag ccacttgatg
    56041 taaaatcaag aactgttgct ggtccaatga atcgagaagg agttaagaaa acttggtata
    56101 ctgatgattt tctaaagaaa catccagttt ttgaatatgg agataaagta aaaattatac
    56161 ttcctggtac tgcctatgac aacaaagtat atacagttaa agataatgga ggaagaatat
    56221 atgttgaaac aaacggaaca tatcatatag atgtactatt agctaatgct agtgaatgta
    56281 aaaaatttgg tagaaagaat ggctatataa ttataggtgg agatgaagaa caaacatatc
    56341 aagttgaagg taataaccaa agtagtacaa ataataactc taaagaagat aaattaatta
    56401 gtatagcaaa aagtaaactg ggttgtaatt atgtgtatgg agcagaaggt cctaataatt
    56461 ttgattgcag tgggtttact caatggtgtt ataaacaaat aggtataaaa attcctcgta
    56521 ctgcttctgc acaaagtaaa gcaggaaaag cagtagattt aaaagataga agcaagtgga
    56581 aagcaggaga cttattatgt agaattggag gaggaagtag taatcatgtt gtaatgtata
    56641 ttggaaacaa tcaaataatt cattcaccac aaacaggaga tgtggtaaaa atagagtctg
    56701 ttaattctta tagaaaagga aaagcataca cacatgtgag aagatttata taagtgaggt
    56761 ggcaatatga gccaagattt attacagata ataaaaaaag ctgcaatgga tgcagtagaa
    56821 acaagcaacc caatgagggt tgtatttgga acaatagaaa gtattagtcc tctaagagtt
    56881 aagatagaac aaaaactatc tattggtgaa atttttctaa tacaaacaga tacatttaaa
    56941 agatatacag ataaaaaaat aggagataaa ttagtcttaa ttcgtatgca aggagggcaa
    57001 caatacttga ttttagatag gatgtgataa agtgttacca agtgataatt tagattatga
    57061 tattgaagat gtatcaataa ttaattttga tgtaagacaa gagccaagta agacatttaa
    57121 acttcatata gaaaagtcta agattgatgg tatttgtgat gatgtagaag cattaaaaca
    57181 gaccatcttt ttgattttaa acacagagag ataccaacat ctaatatata gttggaatta
    57241 tggagtcgag ttgaacgacc ttattggaga gcctatatcc tttgtaatac cagagttaga
    57301 gagaagaatc aaagaagcac taattcaaga tgatagggtt gaaaatgtag ataattttga
    57361 gtttgaaaat ataaagggta aagtacaatg tagattttca gttcatacaa aatatggaaa
    57421 tataaaagca gagaaggtgg tgagtgtata attgtttgag ttaatgacat ttgaaaatat
    57481 aattaaaaga atgttagata gtgtacctaa cacacttgat aagagagaag gttctataat
    57541 atacaatgcc ttggcaccag ttgcagtgga gcttacagaa acatatattg ctatggatga
    57601 attactagac caaacattcg tagatactgc tagttattac tatttagaga agagatgtaa
    57661 agagcgagga attacacctt taccagccac taatacaatt gctaaaggag tttttaacat
    57721 agatattcca cttgattcta ggtttaatct aggagaatac aattatattg caattgagag
    57781 aatatctgaa aaaacatata aaatgaaatg tgaaactgct ggacctatat ttgagttggg
    57841 aaaactaata cctattgaat atatagatgg tcttgaaact gctgaactaa ctgaaatctt
    57901 gataaatgga gaggatgaag agtcagaaga tagtttaaga caaagatatt atgatagcct
    57961 aaattcacag agctttggtg ggaatataca aaactataaa gatgaagtta acaaaataca
    58021 agatgttgga ggagttaagg tttatcctgt gtgggacggt ggaggaactg ttaagttagt
    58081 aataattaac tctaatttca aagtaccatc agaggattta gttaatttag tgcaagaaga
    58141 aattgaccca attggacatc aaggacaagg cttaggatta gcaccaatag ggcataaagt
    58201 tactgttaca ggtgttgtaa gtacaactat aaatatatca gcagagataa catacaaaaa
    58261 tggctacact tgggagaata taaaatcaat tgcagaagaa gcaatagacg actatttaaa
    58321 tgaacttaac atgagttggg aagatgaaga aaacttaata gtccgtatat ctcaaattga
    58381 aactagatta cttagtatag atggagtgtt agatattaca aacacaatga taaatgatgt
    58441 taaatctaat ctaacaatag atagtaacag tatagtagtg agaggtgagg tagttggata
    58501 aagagattaa tctaataaat tacttaccac aaattctaca agataaagaa gaatatataa
    58561 aagtatttaa tgtagaaaac aaagaaataa aaacactaca tgaaaaatta aatgacctat
    58621 caagtgacca gtttttagag gatttaactc caagtggtat aaaaagatgg gaaaagataa
    58681 tgtctataac tcctaaaagt aatgagagtt tagaagatag aaggtttagg atttttagta
    58741 aatatataag taaactacct tactcagaga gatttttaag gaactggcta gatagtatag
    58801 ttggagaagg caattatgaa ttaactatta ataatgctac ttataatata catcttgaaa
    58861 gtgatgctag aaatcaagat tggtttgagg aggttcattc ttttgtaagt agtattaaac
    58921 cttgcaacat gactttagat tacactagag tgcttgtaag taaagacaat tatatgaatt
    58981 ttggtataac aaccctaata ggtcaagaaa taactatata cccttggagt ccaccagata
    59041 tagaaactta tggagaaatt gatgtattaa ctggcaatgg agttggatac caagagataa
    59101 caatatttta ggaggtgata tattggctat agataaaagt tattacacta taattacaga
    59161 tgtagggaaa gcaaagatag caaatgcaag tgtcacaggt aataaagtgg gatttgtaaa
    59221 aattcaactt ggtgatggag gagggagtga atatactcca actgagagtc agacagctct
    59281 caaaaatgtg gtatgggaag gcaatatcgg aaatacaact acagatgaaa ctgcaccaaa
    59341 ttgtataata ttagagagtt taataccatc aagtgtaggc gggtttatga taagagaaat
    59401 aggatattta gatgatgaaa ataatttaat tgccatttct aaatacaaag agtgttataa
    59461 accttctata gaacaaggtg cagtggtaga catgaaggtt aaaactgtgc ttattgtatc
    59521 taatgtaaat aatatagaac ttaaaattga cccaacaata atctttgcaa cactcaaaga
    59581 tatacaagac ttagaaacta aaataggtac tgttaatact aaaattgata caactaaaac
    59641 agaattaaca agcaacatag aaactgctaa aacagagtta aatactaaaa tcgaccaatt
    59701 aatcgcaggt ggctcaaatg ttgcatacac tcaaagggtc gcaattgatg attgggttga
    59761 ggatgcagaa agtggattca aagcaactgt aacacatagt ttattaacac agagaatagt
    59821 tgtaaatatt atagatgcta ctacaaaaga aaatatagtt ccaaatttta aaatagttga
    59881 tgataattca attgagatta gaagtgaagt aaaagttgag ttaaatgtct atgtgataaa
    59941 tggaaatgca gaaactcatt ttataaatgc aactgtagat gataacagag tatctgaaat
    60001 gactacttat tcatctaaga aaatagagga cagattggtt aatatagaag aaaaggtaaa
    60061 tggtggttta tctaatattg caacaagtgt aaatgagttg ataacttatt gttagagagg
    60121 agagtgagaa aatgcagact gaatggaatt ttaattatgc taattatgta caaaatgttt
    60181 cattgccacc tgggcgatat aaattagaat gttggggtgc ttgtggtggt gctgtcgata
    60241 caagcgattg gactgattgt gcaaaaggtg gttattcaaa aggtgagatt gtatttaaaa
    60301 aaagaactaa tctacaaatt tgtgtcggtc aatccggtta tgagaaagtt tctgaaggtt
    60361 caagccttac tagaagtggt tttaacggtg caggcgctgc tggcaaagtt actactggta
    60421 gctttgctta ttctaaatac ggtggtggag caactgatat aagactttat catcctagtg
    60481 caacttgggg taacaccgaa agtttgcttt cacgcatact tgttgcaggc ggtggaggag
    60541 gtatgaaaaa taattttgct tctgcttgtt ctattggtca tggtggtggt tatgtaggtg
    60601 ttaatggagt tggtcgtgac agagattttt gtggcggtgg ttctcaatac caaggtggaa
    60661 caagttacga cacagaagaa taccatggtt cattaggaaa aggaggttat ggtaacatag
    60721 gaataggtgg tggagggggt tggtacggtg gtgctggttc ttattctaat gaatgtggag
    60781 gtggtggaag tggttacgca ctaaataaag atagttataa ggtacccgga tatataccaa
    60841 cacctgaata ttatcttgaa aatatagtca tgactactgg aggtaatact actaaagcag
    60901 atggttatgc taaaataaca ttactacaag cattgccatt tttaacagta tcttcttata
    60961 attctacaca ggcaacattt aaagccgacc acacagaccc tgcattactt acaaagatag
    61021 aatggtttat agatgatgta ctaaaagaaa ctataacaac aaatttaaca gaagagaaaa
    61081 caattaatta tacattagaa gataatgcat tacacacact taaaatagtt gttacagaca
    61141 gtaataatgc tacagcagaa aaagtgttaa gtataagtaa gaatataatg ccactgcccg
    61201 aaaatgtaaa tttaaatgat atatcaacaa aattagttga ggttaatgca ggatttaaag
    61261 ttgggaaaac aagtattata aacactttag cacttaaaaa tatagaagca agtttaaata
    61321 atacacttgt ggagttatca gagaaaataa aaacaagttt tgatagttca gacactagtg
    61381 tgcaagattt acaaaatcaa gtaacacaaa aaaacaatac tataactcaa ttagaaacag
    61441 agttaagtaa aagaaaaaga tttataacag gaacttatac attcacaaaa acggatgcag
    61501 agaattttaa cttaagtata tatgacaaag aaggaacttc aaaaactctt actataccag
    61561 ttaacatggg cttctctcct agtttaattg tacttagtgg agtaactttt agtacaacaa
    61621 gtaaatctta tgtttatttt gataatgttt gtaattcaaa tttttataat tttggctata
    61681 attctgattc tactcatagt aacccgaaag ctgttggtat tcttaatgta tctaatgttg
    61741 ggtattcttc attagtgctt acattatata aattatcaat gtcagaagca gttggaatat
    61801 gggcaaaaga gggagctaca ttaacttaca aaatatatat ttaataaaaa aatgaggtga
    61861 taatatgaac agaaataata gaataattta cgaccaaaca ggcaatatat ggcttcaaac
    61921 tggtgaagca acaggagata tacaagagtg gtcaaaaata actgaattaa attttttgga
    61981 tgttgaattt ggtagtatag actatagtaa acaatatata gagtctataa atccagttac
    62041 aaaagaacca atcatcaaag acatagaagt cattttaaca gatgaacaaa agagattaca
    62101 agcattagaa aaagaattaa gcatgttaaa agaagaaaat aaaaatagag atagtgagat
    62161 agtaaacaca gcctttgagg tagaaaatat aaaattaaat aacaatttat aggaggaatt
    62221 aacatgtata acttattaaa acttatgata gaacaaaaga actatagcac taaagaggat
    62281 ttgcaacaca aaattgatgt attctatgca gtaaatagaa ttacagaaga acaatattta
    62341 gaacttacaa gtttattaaa taaagaagaa acaccagcag aaccaataaa ataggttctt
    62401 tttttattga aagaaggtga ctaaatgact tttaaagagt tagttaataa agttagaaat
    62461 cttgtattag aagcaaagaa tgtaactata gaagatacag aaagtaaatt tacaagtgaa
    62521 aatgtagaag gagcattgaa agaatgtata gatagagcag atgaggcttt tcaagaagcc
    62581 gatagtggaa aaacactttt atcaactgct atcggctctc ctgctacatc agaacaaaca
    62641 tttcaagatt atgcgaacta tattacagga tttaagaata ctatagtaag caaagataat
    62701 actataaata gtttacgaaa tagatatcaa agtacaagtg gattttttat atatgataaa
    62761 gaacattatc caaacggaat agttgtgggt tttaagcctg acattgtttc atatactacc
    62821 acaaatcttg taggtgaaaa atattattgt atatacactc ctttgtttta tttcttttat
    62881 aatgcaagaa cgaaagaaac gtgttttgat agtactgata gtcacagagg catagatata
    62941 aaggataatt catggttacc aaaaggtcca gttaatggcg gagcaggtta tgattatata
    63001 gcagttaagt atcgttaatt gtcaaagact tagataaatt tctaagtctt attttaacac
    63061 aaaataagga ggatgtatgg aagaaattag cataaatcta ttatgtgcag tagcaggagt
    63121 tgtaatatcc tacttagcat ttagaaatag ttcaaacaga aagatacaag atgatacaga
    63181 aacaactaca aaattagaac aacaaataac ttttctgtgt gagaatgtaa gagatataaa
    63241 gcatgatgta gcaaagttta atacaagttt cttagatatc agtgaacgag ttgcaaaagt
    63301 agaagcaagt acaaaacaag cacatcttag aattgatgaa attataaata gaattggagg
    63361 aaaataaaag atggataatt taataagttt tataccagag cagttactaa ttttagtagc
    63421 tgctctttat gttataggag caggttgcaa aaaatataaa caattagata ataaatacat
    63481 tccagtagtg ttattgatac ttggaatagg tttctcaata tggatgctag gattaaatcc
    63541 tgttgcagtc ttacaaggtg taatttgttg gggagttgca ataggtataa atcaaactta
    63601 caaacagttt aaggatggtg aaaagtaatg aaattaacaa aaatattatt actcacaaaa
    63661 atttaaaaaa tttcattaaa tagagtatac ttttatagct aataagtata taataatagt
    63721 acagaactcg taaagcattt atatgctcaa atatacggga cattgatttt tgaaggaacc
    63781 cgccaagctt cttttatagc tcaaataggc gggacagata aatttaccca ctaatattaa
    63841 ttggtgggtt ttattattta aaagtatatc tatgaaaagg tgaaaacaat ggttgaagta
    63901 aaagaagaaa aaacatttga tgaacaaata gatattttaa aaagtagagg attaataata
    63961 aatgataaag aagatgctaa atttgtatta agtaatgtca attattatag gtttacagca
    64021 tatcttctaa gttttaagaa tgatgatggc tcatataaag aaggaactac gtttgaagaa
    64081 gtttatgata tatataggtt taataaggaa tttaggatat tattaacaga tttgttaggg
    64141 agcatagaaa tagcatttag gacatacatt gcatatacat tagcaattaa acatggtgct
    64201 tgtggatatc tagaaaggga gagtttcaaa gatgaaaaat tctatattaa ttttttgaca
    64261 gcattagaga gagaaaaaag taataattca gataagcttt ttattataca ccataaagaa
    64321 aaatatgaag gaaaacttcc catttgggtt gcaacggaaa taatgacttt tggtatgttg
    64381 tcaaaattat attcaaacat gttgccagaa gatactagat acataaaaaa taatttgtgt
    64441 agagtgaata ctttattagt taaatcttgg ttacaatcat taacacaggt cagaaatcaa
    64501 tgcgctcatt atggtagaat atataataat aatttccgta ttataacaat aaaaaacgaa
    64561 tataaaaagt ataacttgga taataaaaag atattttctt atatacttgc tatgaagcat
    64621 ttgactatgg ataaattaat ttggaatagt ttttttataa aacttcaaaa gttaattaat
    64681 gattataata attctataga cttaaagctt attggttttc ctaataattg gatagagata
    64741 ttggctaaat aaaatagtta ctttaagaag tttataaaca cttactatat gtaagtgttt
    64801 ttttattgaa aagaaggagg aaaataaata atgaaaatat gtattacagt aggacacagt
    64861 attttaaaaa gtggtgcatg cacttctgct gatggggtag ttaacgaata ccaatacaat
    64921 aaatttcttg caccagtatt agcagataca tttagaaaag aaggtcataa ggcagatgta
    64981 ataatatgcc ctgaaaagca gtttaaaact aaagcagaag aaaagactta taaaatacct
    65041 agagttaata gtggaggata tgatttactt atagaactac atctaaatgc aagtgatggt
    65101 caaggaaaag gttcagaagt tctatattat agtaataaag gtttagaata tgcaactaga
    65161 atatgtaata agctaggtac agtatttaga aatagaagag ctaaattaga taaaggatta
    65221 tatatcttaa atagttcaaa gcctacagca gtattaattg aaagtttctt ctgtgataat
    65281 aaagaagatt atgagaaagc taagaaacta ggtcatgaag gtattgctaa gttaattgta
    65341 gaaggtgtat taaataaaaa tataaataat gagggagtta aacagatgta caaacataca
    65401 attgtttatg atggagaagt tgacaaaatc cctgcaactg tagttggttg gggttataat
    65461 gatgggaaaa tactgatatg tgatataaaa gattatgtac ctggccagac acaaaatctt
    65521 tatgtcatag ggggtggagc atgtgaaaag ataagttcta ttactaaaga acattataaa
    65581 atgataaaag gtaatgatag atttgataca ctttataaag cattagattt tattaataga
    65641 taaattaaaa agtagcaact aaaagtagtt gttatcttct aatgcctcat tcataataaa
    65701 aaaataattt attatataat aatattaaag tttgtttcta aggttaatat tatgtgatac
    65761 aattcaagtg ggtaaatatt atttgaatga ggtgtgggga tgaaaaattt aagcaaaaaa
    65821 gcagttattt tatcactttc attggtagtt gtatcacctt tggtacataa gataaatgca
    65881 caagatattg agaaaaatag ggaagttaga tatgaaacaa ggaaagctaa taacttagaa
    65941 aatatgacaa tggaagaagc ttttccagat gaaaatttta gaaaagtaat ttgtgataaa
    66001 ctaagtattt tagatgatgg aaatccaatt ggaatttcac aaaaagcgat tatagaatct
    66061 acaaaaggtt taaccttagg gagcaaatca ataaaaaatt tatctggaat taattatttt
    66121 attggattag aaaattttag ttgtagagga aataatttaa tgagtctaga tttaagtagc
    66181 aacataaatt taaaagaatt gtattgtaac gaaaatcaat taacaagtct agatttaagt
    66241 aataatagag agttaacaac gttgcattgt ggagaaaata atctaacaga cttagttata
    66301 gaaaattcta aattagacga attgaactgt agaaaaaata atttaaagag tttagatata
    66361 actaaagcaa ctaatttgac aactctttta tgttttgaaa atgaattgac tagtttgaac
    66421 ctatctaaga atcagaaatt aaaaattttg aaatgtgatt ataataattt aaatgattta
    66481 gatatatcta caaatttaga attacaggat ttaaactgtt cttttaatca attagaaaat
    66541 ataaatttag ataataataa agaacttgtt aagttaattt gtcacaacaa taaattgcaa
    66601 aatttaaatt taaaaaatca tgaaaaactt gtaaaactat attgtaatca agaacaatta
    66661 agtactttaa atgtggaaaa ttgtattaat ttggaagatt taacttgtag tagaagtaat
    66721 ctgaagaatt tggatataag tagcaataag aatttaaaat atctagagtg tgtagcaaac
    66781 aagttaacaa atttgaatat agagaataat atagaacttt tagaattata ctgttatgac
    66841 aatgaaataa aagctttaga tataagtaaa aatattgact tagaaaattt aacttgttat
    66901 aaaaataaat tagatagttt aaatacaagt aaaaataaaa atcttaaata cttatattgt
    66961 tcacaaaatg aattaactag cttggatgta acaaaaaata cagaacttgt aaggctatat
    67021 tgtggggaaa atagattaac cagcttagat gtaagcaaaa acacaaaatt aaaagaatta
    67081 gattggtcaa atcaaaaaaa atcaacatca acaggaggtt cgtcaggaag tggaggaggt
    67141 tcatcatcta caaatgaaga gtcctctaaa cctacttcaa caccatctaa ggaaaaatta
    67201 acaggtgcag acagaaatga aacatcagtg aaaataagtc aaaaaggatg gaataaagct
    67261 gataatatag tgttaataaa tgactctagc atatcggatg ctttatcagc aacactattt
    67321 gctaagtcta aagatgcacc aatattactt actaaaaata ataacttaaa taaattaaca
    67381 gaaaaagaaa taaatagatt agaagcaaaa aatgtgtaca tagtgggtgg attaaagtct
    67441 gttgatgaaa aagtagtgtc tgatttaaag aaaaaaggat taaatgtaat tagaatatct
    67501 ggaaatgata gatatgaaac atcaataaaa cttgcaaaag aattagacaa aaattctaac
    67561 ctgtcaaaag tagtagtggt aaatggagaa aagggactag ctgatgcagt aagtatggga
    67621 gctatatcag caaaagagga aatgccaatt cttcttacta atcaaaatga tgatatgaaa
    67681 gatataaaag acttaatagc taataaaaac atatcaaaat catatgtaat aggtggagaa
    67741 tctttattta ataataaaga agtgaataat acattaccat ctgtaactaa aatagcaggt
    67801 tctgatagaa cagaaactaa ctcaaaagta ataagtcatt tctatagcaa agatacactt
    67861 aatgacttat atgtagctaa gaatggaatg aataaacaag acgatttagt agatgcctta
    67921 tcagtaggag tgcttgcagg taaaactgaa tctccagtag tattagttgg aaatggatta
    67981 gatgatagcc aaaaagagtt aatcaagaat aaaaagttta aaaatataac tcaaattggt
    68041 ggaaatggaa atgaaaaagc atttaatgaa gtagaaaact tagttaaata gattgaaagg
    68101 tagtaactgg aaatagttac tacctccttt tttattcatt ttcagttttt tcaataatta
    68161 tttttccatc ctcaaaagta acaagaacat ccctttcatc aggagagata ttcatctctt
    68221 taatccatga cattggaagt atcaatctgg gtgtaaaaga gcctttgcca cttttattaa
    68281 atccaattct aagttttctt tgctccaata atatcattcc tttctactat taataaatgc
    68341 cagcaataat aaagtaaata ccaaagcaat aagagcttta aaagtaaaac ttattattat
    68401 attaataata tttaaaacta tagtgatacc aagaataatc atacaaattc tataaaattt
    68461 attattcata ttaaattaga aaatgtgtta taatattaga aagaagctac ctagaaggaa
    68521 ggtattttcc tcctaggatt gaaacttata attctttaat caatcttagt attgcgagta
    68581 ctagattaat taaaactaat gtgaaagaga aagcattttt aattttatta aatttgtttt
    68641 ctcttttatt ttttcttctt tctaatctcc ccactttctt tgtcctccct tctaagtttt
    68701 ttattttctt acctcctttc tatatttata ttatatcatc acgtgacgtg aaagtcgata
    68761 aatattccat atttttcaat aaagttataa aatatattaa tataaaatac aaaatataat
    68821 aaagataagt ggatgcttac attatacacc cacttatttt agagttattc ctcatcagat
    68881 ttttttatta taatctcatc ttccttaaaa ataactacag ccttacgttt ttcccttgta
    68941 aatcccattt tttcaagttg gcttaaaggt aaagaaattt tggccgaata agtacctgaa
    69001 cctcctttac tgtaaactat tttagattct ttttgctcca aactattttc ctcctttttt
    69061 atattgtaat gtaacaaata ttaacaataa aatgcttact attaatccta ttatattgtt
    69121 gatattaaaa tgtaaaaata aaagtattat gtctattact atagttatag caactataat
    69181 aagacagaat ttataaactt tatcactcat attttataga aaatgtgtta taatatttag
    69241 aaagaagtca ctaggaagaa gattaaattc ttcctagctt acaaaactat aaatctttta
    69301 ataatttaat tagtttatca attaaattta ttaaaatggg taagatagag agagcagttt
    69361 taactttggc gagtttgctt tctctatctt tttttcttct ttctattcta ctcattttcc
    69421 ttttcacccc ctttctatat ttatattata acatgccgaa ccggcaaaaa caatatttat
    69481 ttccatattt ttcaataaag ttatattgac aaactatatt tttttacaaa taaaaataag
    69541 agtggcaaaa ccaaacttgc caccattttg ccaccgaaaa taaataatag aataaattta
    69601 aactaaacat aataaaacat aaacaacaaa acttacctta ataaaacatt gaaataccaa
    69661 cacttgtaaa aaataacaac aataaacaaa taaaatagaa taatattaca acttaagtaa
    69721 ataataattt tgaataataa tttacggagg tattcatatg tttaaacacg ataaagcatt
    69781 attaaaagaa gtaaaagtag aaagaccaaa tcctcaatat gctgttttaa tgcaagaaca
    69841 gttgggtggt gcaaatggag agttaaaagc agctatgcaa tacttgtccc aaagttttag
    69901 aataaaagac cctcaaataa aagatttatt tcttgatata gcagcagaag agcttagcca
    69961 tatggaaatg gtagcacaaa ctataaattt attaaatgga catgatgttg attataattc
    70021 agttaataca ggcgaaatag aaacacatgt attaactggt ctatcaccag tcttaataaa
    70081 ctcatcagga gctccttgga ctgctaatta cgttacagtt acaggggatt tagtagctga
    70141 cttactttca aatatagctt ctgaacaaag agctaaggta gtttatgagt acttgtatag
    70201 acaaatagat gataaatatg taaaagaaac aatagatttc ttacttaata gagaagaagc
    70261 acataatgct ctatttagag atgctttaaa taaagttaaa gatacaggtt caaatagaga
    70321 ttttggagtt acagaagatt ctaaattata tttcgatttg tctactccag ggccaaatca
    70381 cgatactaag atagatatta atcctccttc ttttgaaaaa cctttaaaaa aataatttga
    70441 tattttttat gttgttttgt tttagtagtt ataaaaatta tttattagaa gaattaatta
    70501 tatgaaaaat taaatatgta tagctaaaaa tgggtataca cttattataa gtgtatatct
    70561 atttgtttat tgcaaaacat ataataaaat aacaaatgag gtggtatttt ggacagtaat
    70621 agaaaaccta ataatctaat aaatgaaaaa tctccatatc ttttacagca tgcttataat
    70681 cctataaact ggtatagttg gaatgatgag gcttttaaaa aagcaaaaga agaggataaa
    70741 ccaatatttt taagtgtagg atattcaaca tgtcattggt gtcatgttat ggaaaaagaa
    70801 tcttttgaag atgaagaagt tgctgaaata atgaatagaa actttgtggc aataaaagta
    70861 gataaagagg aaagacctga tgtagatagc gtgtatatga cagtttgcca agctatgaca
    70921 ggtagtggtg gatggccaat gaccataata atgacaccag ataaaaaacc tttttttgcg
    70981 ggaacatatt tcccaaaata ttcaaggtat aatagacctg gagttataga tttattagag
    71041 aatgtatctg aaaagtggaa tacaagcagg gatatattaa taaaatctgg agatgaaata
    71101 atagaagctc ttaaggatga ttttggtgta aaaaatactg agggtgattt atcaaaagag
    71161 atgttgagtt catcagttag agtatttaag gctatttatg atgaaaagta tggtggtttt
    71221 ggtaatgctc ctaaatttcc aagtcctcag aatcttatgt ttttaatgaa atattatagt
    71281 atagaaaaag acaaagatgt gttaaaaatg gtggaaaaaa ctttagatgg aatgtataga
    71341 ggaggcttgt ttgatcatat tggatttggg ttttcaagat actctactga taaaaagtgg
    71401 ttggctcctc attttgaaaa aatgctatat gataatgcta tgcttactat agctttttta
    71461 gatgcgtata aaataacaaa gaaagagttg tataaagaaa ttgctataaa aactatagat
    71521 tatgtagtta gagagatgaa ggataaagaa ggtgggtttt attcagcaca ggatgctgat
    71581 agtgaaggtg aagaaggtaa attttataca tttaatcctc ttgagataat tgaagttttg
    71641 ggtgaagaag atggaacttt ctttaataat tattttgata taactagtag tggaaatttt
    71701 gaaggcaaaa gtattcctaa tctcataaaa aataaagaat atgaaagaca taatgaaaag
    71761 atagctgacc ttagtaaaaa ggtatttgaa tatagaaaag aaagaacatc tttgcataaa
    71821 gatgacaaga tacttacatc atggaatgca ttgatgatag ttgctttaac aaaggcatat
    71881 agtactttaa aaaatgacat atatttagag tattcaaata agtgtcttaa ctttataaat
    71941 aataatcttg taaatgagtc aggtagatta ttagctagat atagagatgg aagttccgac
    72001 tatttagcat atttagatga ttatgctttt ttaatctggg cgtatataga gctttatgag
    72061 tcaacattta atatgaaata tttagaaaag gctttaaatt tgaatgaaag ctgtatcaac
    72121 cttttttggg attatgaaaa aagtggattt tatatatatg gtaaagatag tgaaaattta
    72181 atagcaaggc caaaagattt gtatgatgga gctattccat caggaaattc tgttcaatta
    72241 tacaatctta taagacttgc gaaaattact ggagataata gacttgaaga aatgtcatat
    72301 aaacaattaa aactgtatgt ggataatgta aagagttctc caactggcta cagcttttat
    72361 atgctttcat tgatgtttga actttattct actaaggaaa ttatatgtat ttttaaggaa
    72421 gattctgatt taattgcctt taaagaattg ataagtgaaa attttatacc aaatgcaact
    72481 tttttagcaa agaaatacaa tgaagaaaac actattatag gttttttaaa taactataga
    72541 ttgaaggatg ataagattag ttattacgtg tgtcaaagta atagttgtag tcaaccaatt
    72601 aatgatttac aaaaattaaa agatatgatt ttaggagtag aataatcata atagtgaaaa
    72661 aggagatgct ttaaaataaa agtctaatca tctccttttt ttgtacaaaa aacagaaaaa
    72721 gagttcctga gaacacctaa tctatgtaat gattgttttg ttaaaaaata aaaatgacat
    72781 tatagttata taaaatattg tactataaaa aagtagtatt atagatgcga tagtattaat
    72841 cgtttttatt tactctcttt cttctttttg caaattcttc aagtgcttca gatttaattt
    72901 tatctatttc ttcatattcc ataaaattag catcttcttc aaagccatct tgttcttcac
    72961 cattaaaacg atacattttt tttagtaaac tccataaggt ctctaattca tctttggtaa
    73021 attcgtgaaa tacatctgcc ataaagttta ttccagtcct actacatgtt accataacct
    73081 tttttcctaa gtctgtaact ttaacattaa ttgctctctt atcatgagga cttggaatta
    73141 catcaacata tccatttttt tcaagattag caactagtct atttatattt tgtttacttg
    73201 tacccatttt tcttgcaata ttatttaatg ttgtttcttc ctctggtaaa tgaagaattg
    73261 ataaaatagt catatactgt cttgaagtaa gtataccaaa atatttatct ccttctattt
    73321 gtattttgtt tgtaagggta aaaagagttg catatgtttg attcattaaa aagagttctt
    73381 ttagttcatt tgaataatcc atgaaatata tctcctttat ttttagatgt tgttttgtcg
    73441 aaaacagaat atcatgaatt aattctaatg tcaatatggt gtcaaaatat attaaagtat
    73501 tactttttta tgtaactatt aattaattaa attattgtat aattttatgt aaaaacttat
    73561 atgtaccaat gataatttct atgaggaatt aataattctt aaatttttta gaaagatttt
    73621 gacttgaaaa tacttgtaat ataatatata aattaatata ctgaataaaa tcaatctgga
    73681 gggataatta tgaagtgtac aaactttact ttcaaaggag aggaaggttt agatatatat
    73741 acatataaat gggaagatga aaatataaaa aaaccaaagg cagttatcca aattgcacat
    73801 ggaatggctg aaactgcaca aaggtatgag acttttgcca aggtacttac taaaaatggt
    73861 tatatagtat atatcaatga ccatagaggt catggaaaaa ctgcaaagat aatagaaaat
    73921 gttggacatt tagctgaaaa agaaggattt agatgtcttg tagaggacat gtatacttta
    73981 acaaatatta taaagaaaga aaatgaagat ctgccaattt atctatttgg acacagcatg
    74041 ggttcatttg caagtcaaag atatataatg gattacagta ataatttatc tggtcttata
    74101 ctatgtggtt caaatggaaa gcaaggaatc attctaaatc ttgctcatct gataatcaat
    74161 cgtgagatta aaaagtatgg aagacgttct aaaagtaata aaataaataa tttgatattt
    74221 ggtggcgaaa taataagaag aaatgaaaag actaagtttg actggttaag tagagataaa
    74281 gaacaagttg aaaaatatat aaatgaccca ttttgtggag tagtgtgtag ttgtggcttt
    74341 ttttatgatt tagttcaagg gttaaaagaa attgaggata aagaaaactt aaaaaaagtg
    74401 ccacttgata tacctattta cataatatct ggagataaag accccatagg aaaaaatggt
    74461 aaaggagtct taagactaag ggatagatat ataaaattag gagtaaaaga tgtaacttgc
    74521 aaactttaca aagatggaag gcatgaattg ttgaatgaaa taaatagaga agaagttttt
    74581 gaggatataa tttgttggtt aaataataaa atagaaatat tgtaataaaa aaatataatg
    74641 atatatttgc tttaaattta tttatatata atatttgaaa agtggattat gtatatgcaa
    74701 agtagaaaag atagagccca gaagtgattt tttgctataa tgccatttat tgaataggtg
    74761 ggtgttatta taaataaatt attaacactc agtattatta tcattgtata tggaatttat
    74821 tttatttaaa attccttgaa agtttaaaag tttaaatata gtaagttgta ataaagagaa
    74881 aatctaaata tttaaatgct atttaatgtg aatctattaa ttaggttata cttaaactta
    74941 attaatagat tttatatttc aagacaatga gatagggttt tagattaaaa tataaccaat
    75001 ggttaaatta cagacatttt gttaactttc cctcgattta ctagtaaata tttttttaat
    75061 atacttaaat tacaacagat gtactaggga ggtatatatg caaattaaaa taggtaaagt
    75121 catacagcgt cttagaaaag aacgaaattt aactcaagaa caattagcaa agtttatagg
    75181 tgtgtcaaca ccagcagtat ctaagtggga gagtggaaat tcttacccag atatagaatt
    75241 attgccttta ttagcagact tttttaatgt gtctattgat aagcttttaa attacaagat
    75301 tgatttaagt gaagaagaag taatgaaaat ttataaagaa ttagaatcag gctttgctag
    75361 aattgaaatt gatttatcaa cagaagaacc aaaagaagaa tttagacaag acttagaatc
    75421 tgtaaaaaag ctttccaata tgtatataga gaagtatcct aaaagctatt tattgaagct
    75481 aaggatatgt tcgctgtatc agatgtattc atataaattt ggtaagagtg aacttaatga
    75541 cagagtaaaa gaaacaacga atattcttga agatatagtg agaaatacag atgatatcca
    75601 aataaaagaa acagctctta ttatattatc aaacgcatat tgtatgttgg aggattatga
    75661 aaaggcagag ttgtatttaa atatgataca taagtcaata ggggatacaa gtgttaattt
    75721 agctatgata tatttaaagc aaaatagact tgaagaagca gaaatattgc ttcaaaataa
    75781 attgtttagt aatgtattta atataagcat ggattgtaag ggaataatta atgtatacaa
    75841 aaatcaatac aaggaattaa agaaaaaatt ggagaataga aattttaata aaaatgcaat
    75901 tgagagagaa atggagtata taaaaaataa gttgctgggg tatgcaaatc tttctttaga
    75961 aataaaaaaa atgctcagtg aagataaagg tgcatttttt agtatgtata tggattatat
    76021 ggaattatct ctaatttttt tattttttaa catgaaagaa gaagcaaaaa aagccttata
    76081 tagtctaaaa gaaatattag aaaaatatcc tatacatgaa agtttggatg taagtcaaat
    76141 gagatttttt gataaggtag agtctaaaaa tttatatact tttaatatat atacaaactt
    76201 gttaattgta cttaatgatg atagttataa tgagcttaga gaagaaccaa tttttaagga
    76261 tgtaattgaa aagattttag atatggaaaa aatgttgaaa aataaagaat aagtaaaaat
    76321 ttaatatagg atttaaagat taatcaaatt aaaagaaagt gtttcaaaat aaaaatttga
    76381 attacctttt ttgtcggtct taaacagtta tttagaaaaa tagaataaag tttgttatat
    76441 aaaatgtaat tttgtctata aaatctcacc tgttttctta actttaagcg tgaaaaagag
    76501 gatgtatcat gaatttttta gttcatgatg catccttctt tgtatgaaat ccaatatatc
    76561 tttattattt aaacaatgga aaagagtctt atttctattt tgagacatct cttttattta
    76621 attatgaagt tttatacagt tcaataaata ggaattatat ttagaaactc atgacattat
    76681 ttcttagata gtgattaaat ttatcatatt ccattttaga taacttttct gggtaagaca
    76741 ttacaatcag gttatgccca ttaaattttt catggtatgg tggatgaatg tgttcataat
    76801 tatttgtctt atattttact ctttcataga acgccttgcg ataaattgaa atctcatcaa
    76861 ttggaaggtc aatttctaaa ataatagttt ttcctttctt atttaaaagc tctaacgctc
    76921 tttgcccata tctattattg cgcatttctg gaaaaatgca gaaatgttct acatagataa
    76981 agtcatctgt ttcccaacat aaaattatgc cgacaaactg gtttttatca taaattaaat
    77041 tgaattgata ttctttattt ttcaaaattt cttcttgcaa agaagatttt ctttgttcat
    77101 gaaatgggaa actaatttta tataattcca tagccttgta atataattta ttttcactgg
    77161 ttcttaaccg ttcaaatttc actttactcc tcctaatcac gaaaattcca atttatttat
    77221 gagttcattt taccatagtc agtatttgca tacaatgtgt tttaagttga gtgtcatttc
    77281 tttcttttat ttatgtttat atctcataga ctaagagata attacttaag acataactaa
    77341 aaactattat attaagcttt gataatctaa aaacagtata tttatggact tttctaggtc
    77401 taaaagtaat cttaataatt ttagaagtta caaaaaagtt acataaattt ggaaagctat
    77461 aatatacata tataatataa ggttaaaact gtaatgaata atattaattt aaaatttgaa
    77521 catggaagga gattattatg gagaaaagag aaaagaggat aataatatca tctttattaa
    77581 gtgtatcaat tttaatgggt ttggtaagta tatattctat attaaataaa gaagacataa
    77641 ttttaactgt taagggtcaa gagcaaaaag tatcttcctt taagaaaaca gttgaggaac
    77701 ttttggatga acagggtgta aagtataatt ctgaagataa gattaatcca agtttagata
    77761 cagaactaaa agatgatatg aaaataaaag ttgttaaggt aactaaaagt aaaaaagaag
    77821 agattgaaaa aattccattt gatacaaagc atgtaaatga tagtaatttg ttaaaaggaa
    77881 aatctaaagt ttatcaagaa ggtcaagaag gagaaaaaaa actagtctat aatttaactt
    77941 accatgatgg aaagttagtc aaaaaagtct tatcaaaaga agtaatatct aaggagccaa
    78001 ctacaaaaat tataaaatat ggaactaaag aaaaagtact aatagcatca agaggagcaa
    78061 atataagagg aggcaaacat atgaaagtgg ttgccactgc atatgcagga gatacaataa
    78121 catctactgg tacaactcca agatggggtg ttattgcagt tgacccacgt gtaataccat
    78181 atggaacaaa agtatatata cctaaactgg gtatgacttt tgtagcagaa gattgtggag
    78241 gtgcgattaa aggtaataga atagacattt ttatgaacag tgagggaaaa gcttcaaatt
    78301 ggggaaggaa aagtatagat atatatctac attaaattag tgaatagaat aactttactt
    78361 gaaggacaaa aaagtataaa atatgaatta actaaactgt tagattattc ttaaaacata
    78421 aaaatatatc taagggggga taagatgaaa atagtctgct taggagacag tttaacgtat
    78481 ggatttggag tatcacgaag taattcatgg acaaacattg taaataaaga gactcgatta
    78541 gaaatagtaa ataagggtat aaatggtgat acaacaagtg gtatgttagc taggtttaat
    78601 gaagatgttg taaaaaattc tcctgatata gtttttataa tgggtggcac caatgatttt
    78661 attgctggtg cgggaaatga aattattaat tctaatataa tggctatggt gcatcagtca
    78721 tattcaaaaa atattatacc tataataggt ataccattaa aaccagatat tccaaatgtt
    78781 aggaaagatt ggagttgttt tactgatttt aatatagtat ctcaaaactt agaatcatat
    78841 agttattgga taaaaaaatt ttgtatgaca tttaatacta atttcgtaga tttttattca
    78901 gaatataata aaaatatgga actagaagga tataaaaaat tatattttga tgggttacat
    78961 ccaaccaaag agggtcatag aataatggca gacattttta ttaattcaat taataagtat
    79021 atagaagagt tatagattac attaaaatgc ttgtttatgc gtcagttgca ataaatacat
    79081 acagtagaga ggggtttatt atggattata ctaaaactta tgaagagtgg ataaagggtt
    79141 catattttga tgaagataca aagctagagt tggagaatat aaaaaataat gaaaaagaaa
    79201 tagaggatag attctataag gatttagaat ttgggactgc gggtcttaga ggaataattg
    79261 aagcaggaac gaatagaata aataagtaca cagttagaag agctactttt ggattggcaa
    79321 actatatatt agaaaacaca acaaaagaag aaacaagtag aggggtagta atagctcatg
    79381 ataatagaca caagtctaga caattctgta tagaatctgc aaatactttg gcagcatgtg
    79441 gtataaaagc atatatattt gatagtttga gaactactcc agaattatct tttgctgtta
    79501 gaagcttaaa tgcaatcgct ggtatagtca taacagcaag ccataatcct ccagaatata
    79561 atggatataa ggtatactgg gaagatggag cacaagttat gccagagatt gcaaatgcaa
    79621 taacagagaa agtaaatagt atacatgatt atagtacaat accaacctta acggaagcta
    79681 ataaaaattt ggtagttttg ttggacgaat cacaagatac taaatttata gaagtagtaa
    79741 aaagccaaat tataagaaaa gatttagtta aaaatgtagg taaaagcttt aagatagttt
    79801 atacacctct ttgtggaaca gggaatgttc caataagaag agcattgaaa gaagttggtt
    79861 ttgaaaatat aattgtagtt ccagaagaag aaaatccaga cccaaatttt gcaggacttg
    79921 attatccaaa tccagaagag aaaaaagctt taaatagagg tatattactc gcaaaagaaa
    79981 aaggagcaga ccttgtaata gcaactgacc cagattgtga tagagtaggt gtagcagtaa
    80041 aaactactac aggtgagtat gctttactta caggaaatca aattggtggt atgctgacac
    80101 attatataat agaaggatta aaagaaaata acaaattaaa agaaaatcct acaataataa
    80161 aaaccatagt tacatcagaa tttggagcag atatagctaa agcaaataat gttgatgtat
    80221 taaatgttct tacaggtttt aaatttattg gtgaaaaaat aaaattattt gaacaaaata
    80281 aaaatagaag ttatgtattt ggatatgaag aaagttatgg ttacttagtt gggactcatg
    80341 ctagagataa agatggtgta gtttcttcat tgttaatatc tgaaatggca gcattttact
    80401 attcaaaagg tatgagttta tatgatggtt taatagaact ttataaaaag tatggatttt
    80461 tcaaagaaca gactatatct ttgactttaa aaggtataga aggtgtagaa aagataaaag
    80521 aaataatatc ttattttaga gaaaatcaaa ttgattatat aaatagtatt aaagtagttg
    80581 ataaaaaaga ttataaaaat ggtatagata atcttcctaa atctgatgtt ttaaaatact
    80641 ttttggaaga tgaatcctgg gtagctataa gaccatctgg aacagaacca aaacttaaat
    80701 tttacatagc tgtaaaagga gctagtgata ttgaagcaga taaaaagatt caaggtttga
    80761 aaaagtatat agatgacatg gtcgaaaaat taaaataaaa tattattatt ttataagata
    80821 attttgtaat aatatttatt tagctgaaaa ttataattta ctttcattga gtagaatatg
    80881 gaaatgttag tagaattgtt attttcagct tttatttgtg ttatttttac ttaaataatt
    80941 atattataga atgaatctga gtataattaa tattgtataa tgaaattaat ttgatagaaa
    81001 aggggatatt tatgtttggt atagataaga aattgattga atatataatt gcaaaatcca
    81061 attacagtga attaagttca aagtcagcag aagtatcttt cttcttaatg ttgtccatat
    81121 ttcctttttt aatatttaca ataagttcta tagcttatat accgattctt catttaaata
    81181 agtatatagc tttgtttaga aatatgatgc cagaaggtgc ttttgctgtg ttatcttcaa
    81241 tcatagtttc tgcaatagac aatagaaacc tgaaattttt agcagtcagt tttgtactta
    81301 ctatgtggac attttcaaga gcagtaaaag ctcttattaa aggaatgaat agagcctata
    81361 aagttaaaga aactaggtct ttttttaaaa ttttatctat atcattttta tttacaataa
    81421 tgcttttggt ccttattttt ttatctatga tatttttagt ttacggggaa aaaataggtt
    81481 attttatttt taatcttgta ggattggatg agatatttat aaaaatatgg gatattctaa
    81541 gatacactgt aggtataata acaataatag tgatatttac acttttatat aaatacactc
    81601 caaataaaaa gttaactatt aaagaatctg cgccaggtgc tatttttgct acttttgctt
    81661 ggtttttagt atcattttta tattcttatt atacaaatta ctatgctaac tatgaagtaa
    81721 tctatggaag tatagctgaa ataattgtac ttatgacctg gatgtatttt agtagttggt
    81781 ctatcgttat tggctatgag gtaaattcaa gattgtattt tagaaagata agacatgaaa
    81841 tgttaaagta aagtatttaa aataaaagag agtatttagt attataaatg taattgaatt
    81901 aataaagaaa tattgacatt taagttaaaa agtctagaat ttttctgggc tttttttatt
    81961 tttagtataa cttgacaaat tttatttaat gggatagttt taatttataa tcatctttaa
    82021 aaagatgact attgataagt aagagataaa attggtaagt atcaaaaaat atactaaata
    82081 aaaattatag tcctaatgag ttaatttctg tattttcaaa taatgcagta tttagtcatg
    82141 tgtttttata tgcgcctgta tttctaatta ctaatatatt agaataagct actgtaatta
    82201 gatttagaaa aaagcgacat aaataattat aaacaaataa taaattacat aaaattaaat
    82261 ttattcacaa gtatatctta taaaatatgt tataattaat agaaaattgt catataatta
    82321 attaagtagt attattataa ataacattga aaggtagtgg ttagaatatg gatacccata
    82381 ataaatatgt aaattttata aaaaatatac ctgtaccttt tttatattgt agaattgtaa
    82441 agagacaaga agatatagaa tatcgagtag aatatataag taagggtatg ggcaaagtat
    82501 tacaattaga agaaggtatt tgtgataaaa atatactaga tgtattgcct gtatttaagt
    82561 ctaaaaaata tttcaaagag ttgttctcaa atgaagtgga ttgtataaaa aggtacattc
    82621 cgacacttaa aaactggata aatataaaaa aacagataat aggggattca tacataattt
    82681 tgtattttgg taaaattgta tttgattata gacagataat cgattccttt gataaaaagg
    82741 aaaaagtagc ttatattaaa gacgaagaag gcatatatat agattgcagt gaaaatttaa
    82801 taccaatatt aaataacaac attaaaacaa cgaaagatat ctttggtaaa aatgatatag
    82861 aagtatgggg agagaataca ggaaaattat ttagagatga ttatagagaa ggagtatcta
    82921 gtaaaaaaag atttttacaa aatctttttg aatatgaaga aacatttttt atggttgaaa
    82981 aatatttttt gtatgatgaa gacgaacttt taggtactat agggatagta gacaatataa
    83041 tatatagtgg ttacagtaat agaaattata actcaaaaga tttaatgaag atgatagaac
    83101 actcaattcc agagaatatg ttttataaag atgtgtatgg aaattatatt ggatttaatt
    83161 caggtttttt gaatttagct tgtatgaata aagaagaatt attagggaag aatagttata
    83221 aaatatcaga agaagaagct ttaatagata agatttttga aagtgataag ggtgtagttg
    83281 aaaataaaaa agtagttacg tttgagttaa atataagtat gaatgatgaa aacaagtgta
    83341 ttgagattac aaaaaggccg ttttttgata gctatggaag tgttattgga ataattggaa
    83401 cagcaaggga tataagtaga agaaaaagat tagaagagga aatggataaa actaggatgg
    83461 aattttttgc aaatttatcc catgaactta gaacgcctat aaatttaata tcatcttcat
    83521 tacaagtgat agaaaaaaaa gaagcagatt taatagaatc aaatgatact ttaaaaagaa
    83581 atctaggtat aataaaacaa aatggaaata gaatattgag gttagtaaat aatgttatag
    83641 actttacaaa aatgcaatca ggatatttag attttaaacc agaagaatct gatataattg
    83701 catttataga ggagatatgt atgtctgtag ctgattttgc aagccaaaat aatatacaac
    83761 ttacatttga tacagaaata gaagaatttt caatgttatt tgattcagaa aaattggaaa
    83821 gaataatatt aaatttactt tctaatggaa ttaagtacaa taagaaagat ggaaaaataa
    83881 atatattttt atatgtgaaa gataatgtat ttaatatgaa aatatctgat agtggtatag
    83941 gtataccaaa agaaaaaata gataaaatat ttaataggtt tgaacagatt gacaatgaac
    84001 tttcttacag agttaaagga agtggtattg gactttcatt agtgaaatct ttggttgagt
    84061 tgcatgaggg aagtatatct ttaaaaagtc aacttggtat tggaagtgaa tttatagttt
    84121 cattgcctgt tagaagtaaa aataatattg aaaaatataa tcataaaaga gaaatcagca
    84181 atgaactaag taaaaaatta gaaatagagt tttcggattt ataagtttaa atataaaaaa
    84241 taaaatttta aaaaagtatt gacaattgat ttagaagggt ttaaaataaa ttacaacata
    84301 ataaataaaa aggcgatgaa taggaagagt aaatctaatt cgattaccag agagaagagt
    84361 ccgttggctg gaagactttt taaattagag ggattgaaaa ctacctagga gctactttct
    84421 gaagtcatct gcattagtag attttagtaa gaatagtcgt tagctgcgtt aaagtgtaaa
    84481 gtgagttttc atgacatatg aaaactaaat taggtggaac cgcgggaata atactctcgt
    84541 ccttatgtta taaggatgag agttttttgt tatttaaaaa tataaacagt aatcataata
    84601 attatagaaa atataaaagc gatgaatagg aagagtaaat ttaattcgac tatcagagag
    84661 gaaagttcac aggctgaaag actttctaag tttgagaaat tgaaaactac ctaggagctg
    84721 tggtctgaag ttactttaaa aagttttagt aagactaacc gttaactgcg ttaaagtgta
    84781 aagtggattt tatcaataaa tgataaaatc aaattgggtg gaaccgcgag tgtagactcg
    84841 tccctttata tagggatgag tctattttta ttgcaataaa agattgaaaa taaaaaaaaa
    84901 tcggaaaatt ataaatttag gaggaaaata aaatggagaa taaagtgaaa attggagtac
    84961 taggatatgg agttgtagga agtggactta tagatataat agataataat aaagaaaaaa
    85021 gaaatataga aatagttgga attttagtta ataatttgga aaaacataag gacaaaaaat
    85081 attctaatat aataactaat aatatagatg atatatttaa taaagatata gatatacttg
    85141 ttgaagtcat gggtggttta gaaccatcat tatcttatat aaaaaaagca ttaaacaata
    85201 aaattcatgt tgttacagca aataaagatt tgttagctga atgtggagat gagcttgcaa
    85261 aattagcaag tgaaaataaa gtaagtatta aatttgaagc ttcagttgca ggaggtatac
    85321 cagtattaaa accaataata gaatcactag aaggaaataa tatagatagt ataaatgcaa
    85381 ttttaaatgg aactactaat tttatattat ctaaaatgta tgatgagaat ctatcttatg
    85441 atatggcatt aagacaagca caagaattag gttttgctga agcaaatcca gagtcagatg
    85501 tattagggta tgatgctgct agaaaactat caatattatc aactctagct tatgacaata
    85561 gagtatattg gaaagatgtg tatttagaag gaattacaga tatagatgaa aaagatattg
    85621 aatatgcaaa aaaattaaat tgtaaaataa aattgattgg tcaaagtaag tatgaaaatg
    85681 ataaagtaag tgcttttgtt agacctgttt tagtagaaaa agataatatc cttgctagaa
    85741 tagacaatga gttcaatgct gtcatagtga atggagattc agtaggagaa gtttcttttg
    85801 taggtaaagg agctggaagt ttagcaacag gaagtgcggt ttattcagat gttatagata
    85861 taatagataa tagagtttca agtatagatt cttttactaa agataaaata caagttaata
    85921 aaatagttag agaaaagtgt ggagcacttc ttagatttaa aaaatgtaat aaagatgaaa
    85981 ttctaaatat agttgagaat tgtttagtaa aattcgatat tttaaatgat gatgatgaac
    86041 ttgctattat ggtttatgct gattctgaat atgaaataaa caacagttta tgtctaataa
    86101 aagataaagg atactgcgaa aaaatgaata aaatgttgaa aataagttaa aaaagaaaaa
    86161 atataagttt atatgtaaca tattttgacg attttaatac tatatagtat gagatgaaac
    86221 aaaacatctc ataaaaaaat taaaattaaa gggagagata tgttatatgg aaaataaaaa
    86281 atgttattca gaagattggt atgaaagagg agaatctaca gctaaatggt tccaaaatga
    86341 tagagaagaa tatgaaagag aagcatatga tgaagataga gaaagaagag gttcaaactg
    86401 tggatgttca gattcaggag aaaatagacc tagaaactgt gaaagattta gaagagaagc
    86461 tgagataaga gaaagagaag caagagaagc attttgtgaa tcttcagaga aaaagaaaga
    86521 ggcattagca tatgaatgtg aagctagaaa attatgggaa gaagcagaaa aatactggga
    86581 tgaatattca aaatacaact ataaaggaat cgaatattta gcagaagctg ctagattatt
    86641 tgatgaaggt atggaatgtg aagctagaag aaatggaaat aatggaggaa acaataataa
    86701 ttgttgccat aaatgccata aatgtaattg taactgctgt agaaaataaa aaaattaatt
    86761 gacaaatcaa tagttaaaat atatcatatt atgtataata aaaagaaaat tcagaaaaaa
    86821 ataatgatta gaagaaatat aagtatattt attagacaaa tagtgctcag ttagtgaggt
    86881 gagtacaata tgattaaact cccatcctct agcttttgat agagggtggg agtttttatt
    86941 tattgatata tcttaaatga ggataatatt gtaaaataaa tgagtatgag attgtaaaat
    87001 taggaggtaa aaaatgaaaa gtattaaaac atcaagtatg aaagaaaagg tagatgaaaa
    87061 gatattaaga gagcaagtaa gttctataat agaagatata agaaataata aggatgttgc
    87121 acttaaaaaa tataatgaga agtttgatag aaatacaaga gatgaattta gaattactaa
    87181 ggaagaaata aaggaagctt ataagcatgt agatgacgaa tttataaata acttaaagat
    87241 tgctgccaaa aatataagag aatttgctaa agctcaaaaa ctaagttttg aaaacccttt
    87301 tgaaaaagaa atttatccag gtgtaatctt aggtcaaact aatattccaa tagagtcatg
    87361 tcttgcatat gttccaggag gtcagtatcc attgttttca acagctctta tgcttataat
    87421 acctgcaaaa gtagcaggag taaaaagaat agtggcatgt tcaccaacta tgaaaaatac
    87481 tgaaaagata aatcctaaga cattggtagc tatggatata gcaggtgctg atgaaatata
    87541 tgcaactgga ggagttcaag ctatagcagc atttacatat ggaacagaaa agattaatcc
    87601 agttgacata attgtaggac caggaaataa gtttgtaact gaagctaaaa gacaatgtta
    87661 tggacaagta gggattgatt ttgtcgctgg gccaagtgaa gttcttataa tagcggatga
    87721 aacttcaaat ccagtttata ttgcagctga tttattagca caatgtgagc atgatttaaa
    87781 tgcaagagga atattattga caaatagctt ggaagtagca caaaaagttg aaaaaaatat
    87841 agaaagtatg ctaaaagatt tgccaacaaa ggacatagca tatagttcat gggaaaataa
    87901 tggagagata atattggttg atgatatgga agaagccatt aaaataagta atttttatgc
    87961 accagaacat ttagaagttg cagtaaatga gtataatgat atttgtgata gattaactaa
    88021 ctatggttct ttatttattg gaaatctttc tgctgaggtg tttggtgact atgtttcagg
    88081 taccaatcat acattaccaa cacttaaagc atcaagatat actggtggtg tttgggttgg
    88141 aacttttatc aaaacttgta caaagcagat atttaatgaa aaagctatac aatcattagc
    88201 acctgtagct gaaaagctgg caaaagaaga gggattatat gcacatgcaa aggctgctga
    88261 ggttaggttt aaaaagtagt aaaaaatttt attttggcag tagtattaga ctgagataag
    88321 gaaaacgctg agaacctgaa taaatactat attttgtggg tctcggcgtt tcttttatat
    88381 ctgtatataa tagaataata ctatctgtgt gtttaaatac taacttaata tttcttttct
    88441 aaataatgtt tatgaaatag ttaatatttt tagttaatac ttgaaaaaaa cttttgctaa
    88501 ctgtgcaaat tcatctgcat ttgtcaatat agcagggtgt cctccctgac taaaaatgtg
    88561 aatacttgct tttgaaataa aagttgccat ttgcttgtac tcttcttcaa gattatgacg
    88621 acacatttcg tcttccttac ttcctgtaaa taaaattggc atttctaatt tacacaattc
    88681 tttatgaaac aaagggcgtt tctcgtttgc acattgtaat agagcttttg tatcaagatt
    88741 aacaacattc tcccaatctt ttccctgaca ccattcatag aattttcgtg cttgaatatc
    88801 ttgctttgat ttttcccttc cagtgattag attatctatg aagttatcat taagagtacg
    88861 tccatcaaag ctatctgcta taattgcttc aactaaatcg ggacgttcta atccagtatt
    88921 aacagctgcc catgctcctc cacttgttcc aattaagcca actttaccac aattcaaatg
    88981 ttcaatcagt gctattgtct gtaaggcttc atcatgccat atgtcaggag aaaattgaga
    89041 aactctatcc gactgtccat tacctaaaaa atcaattaag atacatctaa aattttctgc
    89101 atataatggc acaagtgctt taaacatatt agaagaacca gtattaccat gcaggaaaat
    89161 tatcggttta ccttgtccat attctttata aaaacaagaa ttaccttgat actgaaaata
    89221 tgacatatat tttcctcctt tttatttgat aagttaatta taacaatata ggtatgaatg
    89281 aaaaacctca tgttctttct tagaataaaa atgtgccacg cataaaacgt gacacatttc
    89341 taattataaa ttttgctgtt taagtattct ttgtatgctt ttctctgtca aaaagtattt
    89401 ctctgataac tgcttgatac tcattccatt ttggaaattt atacagattt gagaattacg
    89461 agaagctaag acttgtttgg tgtttgtgtt ttcaccccaa tgctttttgt gctcttgctt
    89521 tttgggaata taaatcactt taccatctat atattcttgc acttgctcaa tcagttcttt
    89581 aggcagtaag tcaatcgaat tttgatagct cattttgcac ctcctaaata attattcttt
    89641 aggattagca aaggctactg ccactcacaa ttaaaaataa aattttttat tatgtacaat
    89701 agcctttgct atgcacaagt tccaattccc ataaactaaa tactcctttc tggtttgaaa
    89761 aattcatctg aacattgatt tcgcttttaa gatagagttc aatgacaaat ttacattttt
    89821 attatatata ttcagataga taattgcaac tgtctttgta tgaggatatt ttattatagt
    89881 caatactata atatgtattt atatcatcaa actaatatga acagttgaaa ggaatatgaa
    89941 caataaaact tagtcaggaa taataattat gaagcagaca attgagaaat ttgattttaa
    90001 agttttattg aaaatttatt gacaaattta acttgtaaat attatactaa acttaataaa
    90061 taaagtttat aaagtaaggt gttgtctatg aaaaatatag ttggaaaacc gcaaacgata
    90121 aaaaaagtaa atgaagattt aataaaaaac attataaaaa atgaaggtcc tataacaaaa
    90181 ccagaaattt caagcattac tgaattgagt ttagctacag ttaataagat tgtagagcaa
    90241 ttagctttga aaaatgaagt taaagtaagt ggactaagtg aatctactgg aggaagaaga
    90301 gctcaattat ttgaaataaa tgcaaactta gaacacataa tagctttata ttattataga
    90361 aattgttgta taggggtagt tgccaattta ttaggtgaaa taatttatca agaagaattt
    90421 aatataagaa tggatacgta tgaaaacgtt aaccaagata ctttttttgt tatagatact
    90481 ctaataaaaa aggaaaaagg aaacaatata agggctattg gaattggtgt cccaggagtt
    90541 gtaaaaaaag gtgtagttaa aaatatacca actataaaaa gttgggaagg tataaattta
    90601 gaaaatttaa taaagagtaa atacaatact aaagtgttta tagaaaatga tacaaatatt
    90661 actactattg ggatttatca aaaacagtat aaagacaaat ataaaaatat ggctcttatg
    90721 tatttagaag atggtattgg ttcaggtata gttataaatg gtgaattgta tttaggttct
    90781 acaaattttg ctggagagtt aagttatcta aatatagaat ttggtaagta taactctaac
    90841 aacttaaatc ttgaagatta tattatgagt ttaagaaaaa gatatttaga aagtaaagat
    90901 aataaattta agaaagaaat tttatctata atatcaaact ttataaggac tcttgtatgt
    90961 gtcctaaatc cacaagctat gattatacag tgtagtatat taaccaagag tgacatggag
    91021 tttatagaaa aagatgtaag caataatgtt ggagaagaaa attttcctaa attaataaaa
    91081 gtagactcat tgagagaagg aagtataaat ggagtaatta gtatgtgttt aaaagaaact
    91141 gactatcaat attccttatc taataaaaaa ggaggatatt aatgtgaaat atttggtttc
    91201 aatagatgga gggggaacaa aaactaaatt ttgtgtaagt gacttagatg gaaacatact
    91261 taaagaacat accactggtt caactaatta taagtcagtt ggaattaaaa aaacatatga
    91321 aaatattaat aatggattta aaaaaatatt aaaagattta tatatcgatt atgacgatat
    91381 tgagtacact gtatttggta tatctggttg tgattctcct aatgactata agattataat
    91441 ggatgaaata ttaaaaattg ggattaacaa agaaaaaata tatctggcaa atgatgcagt
    91501 tttagctttt tatgcacaag ctgattcccc tggtttagta attgtggctg ggacaggttc
    91561 aattatactg ggaattaaag aagatggaga aatatataga gttggtggat gggggtataa
    91621 ttttagtgat ttgggttctg gatatgatat agggagaaaa ttattaaaga aagtattgct
    91681 ttattgtgat gaatgtcatg agtatagtga tttatttagt tgtgtcttgg acttctttag
    91741 agcaaatagt tttgaacaac ttgcatatat gattactgat ataaatgata atgttgaaat
    91801 agcaaactta gcttcattag tgattgattg tgccgaacaa ggtgataaat tggctattga
    91861 aatattaaga gaatcatcaa ctgaactatc taaattagct caagtaatat tgagaaaaat
    91921 atctaatcca atgaaaatgg ataaaagcga aataaatata gttttgtctg gtggtacatt
    91981 aaataaaact gtatatgctc aaatattaat gaataattta aaaacagaaa atacagataa
    92041 aaatttaaaa tttatatctc aagaaaatca gccagtatat ggggggataa gacttgctat
    92101 ggcattagct aataggaggg tcaagcatgg atagaaaaaa ggtaatagta caaattttta
    92161 ctggaggttt taaggctaaa gaaataaagt ttaatgatat aaaatgtaaa ctactagaat
    92221 tattggactg tattgatata gaaaaggtta tcatgggatg gagtgtagat gaagaattat
    92281 atgtagaaac taaaaaacta ttaaataaat ataatgttga actatatctt tggttgccat
    92341 gtttttctga aataggatta cttgaaaaaa gtaatttgct aattgattat atggggaaag
    92401 aagtcaaggg ctatgcttta caagaggatg aaaattttga gttttattgc ccaaataata
    92461 aggaaaatat aaaaaatata aagaaaatat atagtactta ttttagtgat attaaatttg
    92521 atggaatttt tttagataaa ataaggtatg gttctttttc gaataaacta aatggtgttt
    92581 ttaattgttt ttgtaaagat tgtttaaata tatatgaaaa aaataatatt gataaagagt
    92641 cgttaatgag agaaatgaat aatgtgtcta agggagttat agataatgaa gatactccat
    92701 ttggtataac agaatacatt aatggaaaat acaaatttaa aaataaaata tgggaagatt
    92761 tttttgaaac aaaaaatcaa aatatataca aggcattatt agagataagt agttatttta
    92821 aaagtaaggg attgaaaata ggtatagata ctttttctcc ttttatttct tactttacag
    92881 gtcaagattt agaaaaatta caagaagtag cagattttat aaaaccaatg atgtatagaa
    92941 ctacaaaagc tccagctggt ttaccatttg aatttgaaag gtttattgat gaatccatac
    93001 ataagaataa agagattgga aaaagaaatt tcttagatat tttaggaatt aaggagtatg
    93061 aaggagatgt atatcctata gaatttgtac tagaggaaat cgattttatg acaagaaatc
    93121 ttaataaaga tatatatgta ggagttgaaa taaataaaaa ggaaattata tctcctgtta
    93181 cacctaagta cataagtgaa aatatttcaa atataaataa gacaacagta aaaggatatg
    93241 ttttatcttg ggatttgttg tcagcaccaa aagaaaatat tgatgaaatt ataaaatggt
    93301 ttcggaatta gtgaggtgat aaagtgagta agatattgga aatgcaacaa atatataaaa
    93361 gttttggaaa ggtagatgtt ttaaaaggga taaattttga gttagaaaag ggagaagtaa
    93421 gagctctttt gggagctaat ggagcaggaa aatctacact tattaaaatt ttaggaggag
    93481 ttcattctca aactaaaggt aaagtaattt tgactggtaa tgaaataatg tttaaaaatc
    93541 cacatcattc taaagaaaat ggtattagta taatttatca agaattaagc ttgataccaa
    93601 cgcttacagt acttgaaaat atttttcttg gtagagaaat tttaaaagga agtgtgtttt
    93661 taaacaagaa agacatgctt gaggaatata tgaaaatttg tgaggatttt gattttaata
    93721 tagacccaca tatagtagtt tctaatttaa gtgtagcaaa ccaacaaatg gttgagataa
    93781 tgaaagctgt ttcatgtaat tctgaaatta tcataatgga tgaacctaca acatcactta
    93841 ctaataatga aaaagatggg ctatttaaaa taataggtag actaaagtct aaaggtaaaa
    93901 caatagtcta tatttctcac atattagagg aagtttttaa agtatgtgat agtgcaagta
    93961 taatgaaaaa tggaattatg attggaactt atgatgtaga ggatttaact aaattaaaga
    94021 taactcaact tatgacagga aatgataatc acaaacttat tgagaagaag gattatacat
    94081 ttgcaaaata tgaagagcca ccagtactag aagtaaagaa tataagctgg tctaacaaaa
    94141 taaaaaatgt ttcatttaaa gtttatagag gcgaagttgt aggtcttgca ggtcttgtag
    94201 gttcaagaag aactgaaatt ataaatttga tatttggtat agataataaa gatagtggag
    94261 atatttttat caatggtaaa aaagtagaca taacttctcc taaggttgct ataaaaaaca
    94321 aaataggatt gattcctgaa gatagaaaaa atctaggatt aattttagaa caagctatat
    94381 acacaaactc atcatcagta caaattgata aattcaagaa atttttgttt atagatagaa
    94441 ataaagaaat tgagttttct aaaaaaggtg ttaaggaatt aggaataaaa gttagtgatg
    94501 taaagcaaga agtaaaagag cttagtggtg gaaatcaaca aaaagtagta gtttctaagt
    94561 ggttagagaa agatttagat ttaataatat atgatgagcc gacaaaggga atagatattg
    94621 ctgcaaaaga agatattttc aatacaatca aagaattttc aagtaaagga ataggagtaa
    94681 tatttatatc ttctgattta gaagaagtaa taagagtaag tgatagaatt ttagtaacta
    94741 gagaaggttc tattgtagat gatttaaaaa atgagaatat acaggttcaa gatataatga
    94801 acagtatatt taatgtataa aaaatgaaaa tggaggactg agatgaagaa agcttttgag
    94861 aagttaaatt taagagatta tggagtatta ttaggttttt tagctttatg tatagctata
    94921 agtattgcaa ctccatcatt tttaggtaaa caaaatatac ttaatctttt acgacaatct
    94981 tctataattg gaataatttc agcaggtatg acttttgtta taatatctgg aaactttgat
    95041 atatcagttg gagcagtagc agctcttgca ggtgctataa caatgaaatt tgcgactggt
    95101 ggaactaatt tgtttgcatc catgctctta ggtgtagcga tttgtgcagt aataggatta
    95161 atcaatggta tagtagttgc aaagataaat gtaccatcat taatagccac tatggctatg
    95221 gtcactattg taagaggatt gctgttgatg cttacaggag gatatccaat tactgaaaat
    95281 ataccaatac ttgattacat tggaaatgga tatttgttta atataccaat accagtagta
    95341 attttcttta tagtggtgtt agcttcgttt attgtactta ataaaactaa gtttggtaga
    95401 tatgtttatt ctgtaggagg gaatcaagaa gcaagtaaac ttaatggtat aaatgtagat
    95461 tctcacaaag tgaaagtgtt tattattaat gctgtacttg caggaatagc tggaatcgta
    95521 ctaacaggaa gacttgggac tgcaactgcg attgcaggtg aaggatatga tatggatgca
    95581 attgcatctg tagtaatagg aggtacatca gtggcaggag gttctggttc tgtacttaaa
    95641 actgttatag gagtattact tatgagtgtt ataaacaaca gttttaatct tcttggaata
    95701 gatgtatatt tccagtacat atttaaagga ttaataattt tagcagcagt tggatttgat
    95761 tcttatagca agaaaaaact tgcttcaaga taaaaaataa gggggatttt tttatgaaaa
    95821 aattaatgaa acatttagca ttgttgctat cacttgttat gatatttggt ttagttggtt
    95881 gttcaaatgg tggtgacaaa gaaaaaaatg gagaaaagaa aatagcagta ttactaccag
    95941 gttcaacagg ttactttgta gcaactaaac aaggtataga tgcaaaatct aaagaattag
    96001 gtgtaagcgt ggaatatgca gatgctcaat gggatgctag taaacaatta tcacaagctg
    96061 aagattttat ggctaaaggg gtagacatga ttgcattatg tggagttgat tctgctgtaa
    96121 gtgagagaat agttaaagct gctaatgatt cagacgttcc tatagtagca tttacaaatt
    96181 ctataggaag taacccaact ggagaattta aaggtttagt tacatatata ggacaaaatg
    96241 aggaagaaac aggagcatta actggaaaaa ttgctaaaaa cttattagga gaaactggtg
    96301 ggaaagctgt attaatagaa ggagtaccag gaactactcc acaagtatta agaaaaaaag
    96361 gtcttgaaaa agaattaaaa gatagtaata tagaaatagt ttataatcaa acttcaaatt
    96421 gggagaaaga gcaagcttta aaagtaacag aagatttaat tcaaaagaaa actgatttta
    96481 atgttataat atgtcaagat gataattctg ctacaggtgc aggtcaagct ttaaaagatg
    96541 ctggtcttaa ggataaagtt aaagtcatag gtttgggtgg aagtaaagat ggattaaaag
    96601 ctataactga tgggttaata gatggtacaa cttatatgtc tgctgtagaa gaaggtggat
    96661 tagtcataga aaaggcatct aaattcctta aaggtgaaaa aatagaacct gttacacaaa
    96721 ttaaacaagt tgaagttaac aaagataata tttcagagtt caagggtgaa tggtaaattg
    96781 tcatagataa taaataagat ttttagagtt actttagaaa ctatataaag taactctttt
    96841 tttaatttaa tttagtgata aattattgaa tagtatttct aaacaaataa aaaattaata
    96901 taaacaaaga cttaattata ctaaattata agtaaaacta atataaactt atggaaaaaa
    96961 ggaaaacgtc taaagtattg gaattactat agtgtaggtg tggtattaaa aaaacataaa
    97021 aaaacataaa aaaattgttg aaaaaaatat agaaattttg tataattaaa gatttgaaaa
    97081 gtgcggtata caaagccaat tcttttgtat ataatatata taaattcaga aaaaggaagg
    97141 gatatgtatg gccaggcggt tatttttaga aaggattgga cttatatttt taggttcagc
    97201 aatattagca tttggagttt ataattttta ttatttaaac aacataacag aaggtggagt
    97261 gttaggtatt ttactactgt taaaaaattt attcaatata caaccagcaa tagcaaatgt
    97321 tgtaatagat ggtttactac ttttagtagg atataaattt ttcggtaaaa aattccttat
    97381 atattcaata gtagcttcta taactttttc agtgttatat gacttatttg aagctatagg
    97441 acctctagta ccacaatcac aaaatatgct tttatcaact attttggcag gtgtaactgt
    97501 tggaactggt gtaggtatag tagtaaaagc aggttgtgca tcaggaggag acgatgcttt
    97561 agcattagta atttctaaga ctacatcttt gaacataggg caagtttatt tagcaacaga
    97621 tgttattgta ttgttgttat cattatttta tctatcagcg tttgatatct tttattcttt
    97681 gattgctgtt acaattagtg gcaaggtaat tgattttatt tattatcatg gtaaaagttt
    97741 ggatatggat ataagtaatg atatagttcc agaatgttaa tataaattaa ataactttag
    97801 attttattag gggtggcaga tttgccacct tttttgtgtc taaatcttta tagaaagtat
    97861 aatcccatct aggtttttgc aaatctcaaa tatagaatta tgttggaatg actgggaata
    97921 cgattgctag atgtgcattt taaaaaccca attttatatt tatgaaatac taatcattaa
    97981 tggatgtttc ttaatcctat ctttatacct aaaatgataa gataaatgaa gtagcaatac
    98041 aaaactaaaa tttgtaaaag agattaaatt aaatggagga gctaaaatgt tggatatagt
    98101 tatgatagca ttgttattca taggatttgt ttccatgaag ttacttgctg attggtgtgg
    98161 gaaacaaact gaaaaaaaat aatgtaatgt atggagggat tacctatgtg gtttctggca
    98221 gttgtaatta taatgttaat aatatatttg gtatatgcgc ttattaatcc tgaaaaattt
    98281 taaacagtat aaggctaata agtaagttga attgggggga acaattttta tggtgcagat
    98341 agtaatagtg ttagcgattt ttatgatttt agtaatacct atgggcaagt atttatatca
    98401 tatagctact aatcaaaaaa catttggaga tagactattt gataaagtgg acaattttat
    98461 atataaggta tgtagtatag ataagaaaaa agaaatgaac tggaaacagt atgcattagc
    98521 tttattattt acaaatgcag ttatggtatt tataggatat atcatactta gaactcaaag
    98581 tatgcatatt tttaatccaa gtggaattaa aagtatggaa caaggactat catttaatac
    98641 aataataagt tttatgacaa atacaaatct tcaacattat tcaggtgaat caggactttc
    98701 atactttagt cagatgacag tgataatata tatgatgttt acatcagctg caacaggata
    98761 tgcggctgct atggcatttg taagaggtct agtcggtaaa aagaaaacat tgggaaattt
    98821 ttatgtagat ttaattagga taacaacaag agtactttta ccaggagctt taattattgg
    98881 gcttatatta gttacacaag gagtaccaca aacttttgct gggacagaaa cagtgactac
    98941 tatagaagga aagcttcaag atatagctag aggtcctgtg gcagctcttg aatcaataaa
    99001 acatttagga acaaatggtg gtggattctt tggttcaaat tcatcacacc catttgaaaa
    99061 tccaacaata atatcaaata tagtagaaat attatctatg atgatattac caggagcttg
    99121 tgttgttgca ttcggtcaca tgataaagaa taaaaaacaa ggttgggttg tgtttggcgc
    99181 aatgtcaatc atatttttaa taggtctagt agtgtgcttt aaagcagaaa gtgcaggaaa
    99241 tcctatttta tcacaattag ggcttaatca aagtatggga agtatggaag gtaaggaagt
    99301 tagatttggt atagcacaat catcattatt cacaacagtg actacttcct ttacgacagg
    99361 tacagttaat aatatgcatg atacactgac tcctttagga ggattagtac cacttttaaa
    99421 tatgatgcta aatgtagtat ttggtggtaa aggcgtaggt ctgatgaata tgttgatgta
    99481 cgctataata gcagtattct tatgtggatt aatggtagga agaacaccag agtttttaac
    99541 taagaaaatc gaaggaaaag aaatgaagct tattgcttta cttattatat tacatccact
    99601 tttaatacta atgttctctg gtctttcagt agcaatacca gcaggacttg aaggaatttc
    99661 aaatcctgga ttccatggat tatcacaggt attgtatgag tttgcatctt cagcagccaa
    99721 taatggttca ggatttgaag gtctaggaga taacactatg ttttggaata taacaacagg
    99781 tatagttatg ttctttggaa gatatgtgtc tattatagta ctactagcaa tatcaagttt
    99841 gttagcatct aaaaaagctg taaatgaaag tataggaaca cttagaacgg ataattttac
    99901 atttacaata gttttagtac ttgttgtttt aattgttggt gctttaacat ttttcccagc
    99961 cttagcgctt ggacctattt cggagcatct agtgttgtgg cactaaaaaa ttgggaggga
   100021 gtaaagtttt atggaaacta aaaaaacaaa gtttattaca aaagatattt tcaaaacttc
   100081 cattatagaa gcttttaaaa aattaaatcc taaatatatg atgaaaaatc cagttatgtt
   100141 tgttgtagaa attggattta tagtaacatt gatacttaca atagtaccta gtttgtttgg
   100201 tgatgaaggc aataacttaa gagcttataa tgggattgta acaataatct tatttataac
   100261 agtccttttt gcaaattttg ctgaagctgt agctgaagga agaggtaaag ctcaagcaga
   100321 tacacttaag aaaactagaa aagatacagt agcaagggtt atagatacat taggaaatga
   100381 aaaaatgata agtgcaagtg agctaaaact tggtgatatt gttttagtaa atgctggaga
   100441 agttattcca aatgatggag aagttataga gggtatagct tctgtggatg agtcagcaat
   100501 aactggagaa tctgcacctg tcatgagaga atcaggtgga gatttcgcat ctgttacagg
   100561 tggtactaca gttgtaagtg actggttaaa gataagaata acaacaaaac caggagaatc
   100621 gttcttagat aaaatgatag ctcttgtaga aggtgcttca agacaaaaaa cgccaaatga
   100681 gattgcttta aatactttgt tagtagggtt aacacttata tttatggttg ttttaatatc
   100741 tctttatcca atggcaaact atgcaggtgt aaagattcca atttctacta tgatagctct
   100801 tttggtatgt ttaataccaa ctactatagg tggattgttg tcagctattg gtattgcagg
   100861 tatggataga gtaactagat ttaatgtaat tgcaatgtca ggaaaagcag tagaagcttg
   100921 tggagacgtt gatactatga ttttggataa gacaggtaca attacttatg ggaatagact
   100981 tgcatcagaa tttatagaag ttggaaatgc aggttcaaaa gatttaataa attattctgt
   101041 tatgtgttca ttaaaagatg atacaccaga aggaaaatct atagttgatt taggtatgaa
   101101 attaggttca acaggtaaga caaaagaggc agaggaagct gagtttgtag aattttctgc
   101161 acaaactaga atgagtggta ttaacttagc tgatggtaga gctataagaa aaggtgctta
   101221 tgatagcata ataaaaagag taaaagaatc tggtggtaca gtgccagaag atttagaaga
   101281 aaatgtaaat cgagtagcta aactaggagg gacaccttta gtagtgtgtg tagataatga
   101341 gatatatgga attatctact taaaagatac agtaaaatca gggcttgtag aaagatttgc
   101401 tagacttcga gagataggaa taaagacaat aatgtgtaca ggggataatc ccttgacagc
   101461 agctacaatt gcaagagaag ctggagtaga tggatttatt gcagaatgta aaccagaaga
   101521 taaaatagat gcaataaaaa aagaacaatt agagggtaaa atagttgcaa tgacaggtga
   101581 tggaacaaat gatgctcctg cacttgctca ggcagatgta ggtcttgcaa tgaatagtgg
   101641 tacaacatct gcaaaagaag cagcaaatat ggtagattta gattcagacc caactaagat
   101701 attggaagtt gttgaaatag gaaaacagct tttaataact cgtggggctt tgacaacatt
   101761 tagtatagca aatgatgttg caaaatattt tgcgattata ccagctatat ttactcttgc
   101821 aatacctcaa atggagatat taaatgtaat gaaactttct acgtcattta gtgcgatatt
   101881 atcagcttta atatttaatg ctataattat cccatgttta atacctcttg caatgaaggg
   101941 agtaaaatat agacctatga aatcacaagc tatgttaatg agaaatatgc ttatatttgg
   102001 tcttggtgga gttatagtac catttttagg aataaaatta attgatttat tgattacacc
   102061 tttagtaatg gttcttaatt taggttaata aatggaggat ataaaaatga aaacattaaa
   102121 gccagcatta cttgtaagta ttgtattgtt agttgtttgt ggacttgtat atccacttgt
   102181 tttgacaggt gtaagtcaag ttgcatttaa agataaagct aatggaagta tgatagaagt
   102241 aaatggtgta aaagtaggtt cagaacttat tggtcaaagc tttacagatg cgagattctt
   102301 taagggaaga gtatcatcag taaactataa tacttataca aaagaagatt tagtaccaga
   102361 taaagatgga aatacatctt atggaggtgt atcatcaggg tcttttaatt atggagctac
   102421 aaatccagaa cttcatgata gagtacaaaa agatatagaa aagtttttaa aggataatcc
   102481 aactgtcaaa agagaggata taccaacaga tttacttaca gcatcaggtt caggacttga
   102541 ccctaatata agtccagcct ctgcaaaaat tcagatacca gctatagcaa aagcgtctgg
   102601 aatatcagaa agtaaattac aaaaaattgt agatgataat acttccaaaa aactttttgg
   102661 agttttaggt gaagatatag ttaatgtatt aaaagttaat gtagaggtcg caaaaatatt
   102721 aggtcttata tagtattttg tggaatttta gcaacaaaat attacgcaag atttaattta
   102781 aaggttaaat tttaaagagt gaaaatcgat aatgattttc acttttttat ttgaatatta
   102841 ctaatatttg gaataaagtg attgtaagta taaaatccaa aaaaaggttg cattatcaaa
   102901 atgataatac tataatatat ttatcgttat caatttgata atagatttgg acatatagga
   102961 ggaaatagta tgttatataa taacgcatta gagttgatag gaaacacacc tgtagtaagg
   103021 ctgaataatt taggctgtac taatgggtgt tctaacatat atgtaaaatt agaaaaagta
   103081 aatccagcag gaagtataaa agatagagct gtttatgaaa tgttagaggg tttagagcaa
   103141 agaggagaat taaaaaaggg agatgtacta gttgaagcaa ctagtggaaa tactggtatt
   103201 gcattatcta tgataggaaa attaaaagga tatgaagtag taatcgtaat gcccgaaaca
   103261 atgagcgttg agagaagaga tttaatgaag gcttatggag caaatttggt gcttacagat
   103321 ggtaaagctg gaatggcagg ttccatagaa aaagcaaatg aacttttaaa agaaaatcca
   103381 aactataaaa gcttaaaaca atttgaaaat aaagataatc caaatgcaca ttataaaaca
   103441 acagcagttg aaattatgaa tgatgtcaaa gatttagata tattcgtatg tggagttgga
   103501 acaggtggta ctttaatagg aactgcaaga tatttaaaag aacaaaatcc aaatataaga
   103561 gtaattgcac ttgaaccaaa aaaatctcca gctatatcag aaaacaagac tggacctcat
   103621 aaaatacaag gaataggtgc taactttgtt cctgaaaatt atgattctag tgtagttgat
   103681 gaagtaatat tagtagatga tgaagatgca tttgatacag ttaaattact tgcagcaaaa
   103741 gagggaattt tagtagggat atcttctgga gcaaatatat ttggtgctat agagatggca
   103801 aaaaagtatc cagataaaaa gatagttaca gtagctccag atggagttga taagtatatg
   103861 tctatgggaa tattttaata attttatttg agggagtgaa tactttgttt aagaaaataa
   103921 ataaagatat tgaatatata atgaagaatg atccagcagc taggtctaag atagaagttt
   103981 ttttacttta tccatcagtt catgcaatga taatgcatag gatggctcat gctctttata
   104041 agaagaagaa gctttttaca gcaagattaa tatcccagat atccagattt atgactggca
   104101 tagaaataca tcctggtgct aaaatggggg aaggtatatt gatagaccat ggaatgggtg
   104161 ttgtaattgg agagacagcg gaagtaggga atagggtgac aatatatcaa ggagctactt
   104221 taggagctac aggaaaagat actggaaaga gacatccaac tgttggtgat gatgtattaa
   104281 ttggtgctgg aacaaaaata ctaggacctt taaatatagg ttcaaattca aaaattggtg
   104341 caaattctgt tgtcgttaag gatgtaccta atggtgcaac agttgttggt ataccagcaa
   104401 aaatagtaaa aataagaaac ctagaacctg taaaaaagaa taaaaaagaa gtgtcctatg
   104461 agtatgatga attagataat gtatattata tataggattt atataactat aaaataaact
   104521 ttataaaaat tattttaaaa ggtatttttt tcaaatttga ggacataata aaaaagaact
   104581 gaatgttaca gttttggttc atcaatcttt gataaacaag attttaaatt tgtagcgtct
   104641 aggaggattt tattatgaaa gcaaatgtta atcaagatac ttgtataggt tgtggattat
   104701 gtccatcaat atgtccagaa gtatttgata tgaaggatga tgggaaatca catgttatag
   104761 ttgatgaagt accaagtgat gctgaagaat cagcagcaga agctagagaa agctgtccag
   104821 ttgatgcaat agatgtgcat taataaaata aatgcctata aaaattgaat tttcaatttt
   104881 tataggcatt tgtcttttat tcagttagta tttcaacacc tgtttctgta actaaaacca
   104941 tacattccca ttgagcagat aatttaccat cttttgtata aatagtccaa ttattttctt
   105001 catcaacaaa aatttcgtga gttccttcat ttaccatagg ttctattgtg aatatcatcc
   105061 caggaaccaa tagcatctca gtcccttttt tggatacata acttacaaaa gggtcttcat
   105121 gaaagcttaa tccaactcca tgaccaccta tttctctaac aacagagtat ccatttttct
   105181 ttgcataaga gttgatagca tcacctatat ctcctaaaaa tccccatggt ttggcaactt
   105241 caagaccttt ttggacacat tcctttgtaa cttgaactaa tttttttgca ttttcattaa
   105301 cattacctat cataaacatt cttgaagcat ctgaatagta tccattaaaa atagtagaaa
   105361 catctacatt tataatatct ccatctttta agataatgtc cttacttgga ataccatgac
   105421 aaacttcatt atttactgat gtacatacac ttttaggaaa tccattatag tctagtggag
   105481 cagggatagc tccattttgt agtgtaaagt catgaaccaa cttatttata tcttctgtag
   105541 acattccaat ttcgatttta tctgaaatat aatccaaaat ttttgtgttt attacagcac
   105601 ttttttttat ttcctcaatt tgactttcat tttttataat atcatgagtt ggtacaatat
   105661 gacctaactt agcaaatgaa tctattttat tatccatatc catatgacat tttttatatt
   105721 ttttagtact tccacaccaa cagctatcat ttctatttaa cttcataact tttcatcctt
   105781 cttttattat ttatttaaat tatgggttac ataaactatt ttaaaacata accattataa
   105841 atattataac ataaatacta agaaatcctt tatagatagt gatttattca aagtataaat
   105901 tattatatgg ttattgttga tgaaaagagg atagttaaat gtattattgg atattagcgc
   105961 acttaatagt ttagttcaag tttttcaaga aaatcatatg ttagaggaca attttccttt
   106021 aaagtatttt ttgaatcttc atcaagataa taatgtacaa atgattctgc aaaaaattct
   106081 tctataaact tgcttatata tgcatgtgca acttgcttag ggtcataaag cttatatctt
   106141 tcctgagcaa atacttccat aaattcttca gaatttgatt ttttatttaa aacattttta
   106201 tctatagcat gtgcagtttc atgtaattct aaattttttg atgaatgtac atttgcatag
   106261 ctaggattac tataacctat tttagccact atagaattat ttctatatat accaggtaca
   106321 tctttccaag tcttgcctga tcttacccaa catggaggta attgatattt taaatcacta
   106381 aattctggtt catcagttag atttgaattt attaatttta tttttatatc cttttcttta
   106441 agtgtctgta aatatttact atttattttt gcaagtctgt ttttcatatt ttcaacttca
   106501 tctttatcat aattcaagtc atcaggaagt ataagcattt gttcaattat atctatacta
   106561 ctgtctttta tattttcaga ttcttcatca aatttatatt gaagagtatt attttcatag
   106621 atagttatat ttgtattatt ttctatagaa taagagtgaa tatcctctaa atctaaaata
   106681 ttcatttgtt gtaaaatatg ttttgtttcg ccactccata ctactaaaga aagtgaatta
   106741 aaattaatta gtggattttc ttttgctttt atatcattgc ttatatctac atcaaataca
   106801 tattcaattg agtcttctat gttaagacta tctgtattct ttttaatata taaatacgct
   106861 tgttttaagt ctatataaat ctcatctaaa gattcgtcat aaaattctga taaattatta
   106921 gtaaagagtt cttcacttaa aagttcattt ttatcagtta tactttcaat taaaatatta
   106981 atttctttta tcatatcgta aatacttatt tttctatttg ctttttcact agatacattg
   107041 catggcgcaa gagcaatgca ataaaaatct ttttcttttt tataaaaggc tttaagtgat
   107101 tttgataaaa gtgtaaagtc tacacctatc tgtaagttga ccttaagtga gtcattttgt
   107161 aataattcag tattatttct tttagctgta tttaaattgt tttccataat cattgccccc
   107221 tttttattag ggtatcataa tttttttata tgtgtcaatt tatttttttg aaaattataa
   107281 tttttttgaa aattttattt tttataattt gtgaattttt tattatagaa ataaatatgt
   107341 tattattatg tcaagattta gcattagatt catgtagagt atgttttata catatattat
   107401 aattaattct ttgaagattg catattcaaa atacacacca ttttttttaa ttctataata
   107461 taatatttat atatttaatg ttaggatgtg atttaaggtg tattttacat atattataag
   107521 atgtaaagat gattctctat acactggata taccagtaat atagtcagaa gaatgaatga
   107581 acataagtta ggaattaatt caaaatacac aagagcaaag ggatttgaaa aactagaagt
   107641 ttattttgtg accaacacaa aaagcaatgc tatgaagtta gaatattata taaaaaaatt
   107701 aactagaaat aaaaaattgt ctataataaa aaacccaagt atacttataa atttaattga
   107761 taataaagaa gattatatta ttggtaagga aatagaacaa ttaacataaa tatttatagt
   107821 aacattataa tgggtgcata tagtgtaaaa acttgacaat aaatactatt gtaatataat
   107881 gaagttataa atatagtaaa ttaaaatagc taggggagcc aagagctgag aggtataccg
   107941 acccttacac ctgatctgga taataccagc gtaggaaagc ttagtaaaaa ttcaagtatg
   108001 tattatttgt gatatatgct atttctaagc tatacctatt gtaggtatag cttttttaat
   108061 taagttattt aaattaaact ttaggaggca acaatgagta attataaaat accaacactt
   108121 acaatagctg gatctgattc atctggagga gctgggattc aggctgattt gaaaacgttt
   108181 agtgcaattg gtacttatgg tatgagtgta ataacagcta taacagcaca gaatactaaa
   108241 ggagtttttg ctgtagagga tttaaataag aaaataataa aaaaacaaat agaggcagtc
   108301 tttgaagata tacctccaag agctgtaaaa ataggaatgg tttcaagtcc tgagattata
   108361 cttgaaatag ttgagaatct aaagaaatac aatccaaaat atttggttgt ggacccagta
   108421 atgatatcta aaagtggata ttatctatta aagccagagg caaaagaaaa cttaattaag
   108481 tatttgatac cacttgcata cataattaca ccaaatatac cagaggcaga agaaataaca
   108541 ggaataaaaa tacataatgt agatgatatg aagagagtag gagaagaaat actacaactt
   108601 ggacctaaat ttgtacttat gaaaggaggt catttagatg gagaagcagt ggatatttta
   108661 gttggtaaaa atatatttaa agtttataaa agtgaaagaa ttgataaaaa aaatacacat
   108721 ggaacagggt gcacattatc ttctgcaata acatcttatc tagcattagg atatgaaata
   108781 acagaagcag taaatctaag taaaatctat ataacagaag caataaaaag aagttttgat
   108841 ataggtcatg gagtaggacc agtacatcat ttttataaat ttgagtaata aaaaaatatt
   108901 ggaggtagaa tatgtataat ttaattaaag atgtaaaaaa attaaatcca ttggtaattc
   108961 attatactaa taatgtaact ataaatgatt gtgctaatgt aactttagct gtaggagcaa
   109021 gtcctcttat gagtttttca tatgaggaag tagaagaaat ggtaagtgta gcaaactctg
   109081 tagtaataaa tataggaact atgaactcaa atatgttgga tttattccta ttagctggaa
   109141 aagcagcaaa taagtacaat aaacctgttg ttttggaccc agttggagta tttgcaagca
   109201 aagcgagagc agaacttaca agtagacttt taaatgaagt caaatttagt gttgttaaag
   109261 ggaatgtatc agaaataaag tttataggtg gctttaatgt aaggggtaaa ggtgtagatt
   109321 catttgatga agaagaagat tctactgaga taataagaaa gattgctgaa aagcttgaat
   109381 gtgtagttgt agcaactgga aaaatagata taataactaa tggtaaaggt acatataaaa
   109441 taaacaatgg aactgataaa ttaaaaggaa ttacaggaac tggatgtatg actgctagct
   109501 tgattgcaag ttttatggct gttactgaga atatattaga agcagcaaca atgggtgttc
   109561 ttacaatgtc tttaagtggg gaattagcta atttaaataa tccaccaata ggtacattta
   109621 aagaaaatct tatgaatgct atttatcaaa tggatataga tactttaagt aaaaattcta
   109681 atattgaatt tttaaattaa taaagagtaa gggagactta aaatgattga taaagaatct
   109741 ttaaaaaaat gtttaaagtt gtatttagta actgactctg aaatgcttaa aggtagagac
   109801 ttttataaat gtcttgaaga tgcaatatct tctggaataa caactgtaca acttagagaa
   109861 aaaaatgctt ctggaagaga gtttttaaga aaagctatga aacttagaga aataactaaa
   109921 agatatggtg ttaagtttat aataaatgat agagtggata tagcacttat ttgtgatgca
   109981 gatggagtac atgtaggaca gagtgacatt gatgttagag aggttagaaa gcttatagga
   110041 aaaaataaaa ttctaggagt atcagcaaga actttagaag aagctatttg tgcaaaaaat
   110101 gatggcgcag actatttagg tgtagggtct atattcacaa catctactaa attagatgca
   110161 aaatcagctt cgtttgaaac tgttaaagaa attaaagaaa aagtagacat tccatttgta
   110221 ctaattggag gtataaattt agacaatata gataaactta aatgtttaga aagtgacggg
   110281 tatgctataa tatcagctat attaaaagct gaagatatct ctaaagaagt ggaaaagtgg
   110341 acattaaaaa tataaaattg gctctggtag tgaaaaaaat ggaaaaattt gatataatct
   110401 aagagtaaaa tttaagcaat tataaatgat aaacttttct acatatactt tttaatcaag
   110461 atatatgtag atttggttaa aaaggagcta taaatgatta ggatattgtt agtgtgtgtt
   110521 ggaggcatgt cttctaccct attggtaaat aaaatggaga aggatgcaaa aaaaagaaat
   110581 atagactgta aaatatgggc agttggagaa ggagatataa aatcggagct tgataacttt
   110641 gatattttac ttcttggacc acaacttaga tttatgcttg atgacgtaaa gtctatagtt
   110701 ggagatagag ctcctgtatc tataatagat atggtaaact atggtacttg taatggtcat
   110761 gctgtgttaa attcggtttt agaaatatta aaataaataa taaaagtgga ttctatataa
   110821 tagagtccac ttttattatt tgttattaat aggcttaaaa cttagcttac catttctttt
   110881 tttaatctcc acatagcaag tgaaaaactt gaacagcaca atattaaaaa tagtaggata
   110941 acaggcagta tatctccaat aagaatagtc tcaccaaata ttaagctacg taaagcgtta
   111001 ataacatggg taaatggatt gagcatcact gctactttta atcctccaga taaactttct
   111061 atagggaaaa gagctgaact taaaaagaaa ataggaagta caattgcagt cataattgtt
   111121 tcataaacta tttcatttgg caataataaa cttatagaat aagctagact tgataaaaag
   111181 aaggctgtca taaatatcag tattatcata agtaggattc caccaatgcc agattctatc
   111241 cttactgaga agaatatact tactatacac aaaatagtta cttctatgaa agaaactaag
   111301 atagcttcta ataattgacc aaggacgatt gaatacctgc tgataggtgc aattaagact
   111361 ctatagaaac ttccactgtt cttcattata aagtttataa taccaccact actacaagaa
   111421 gaaaacacaa ccagtacaat gatacctggt agtataaaag cagtataatt attgatattt
   111481 atattattca tagtttggtt tgcaatagaa ctataaagca caagccaaag aaaaggttgt
   111541 aatatagtaa ctacaaatga gattggattt ttaaaacgcc acttcatact acgccataag
   111601 atatttaaca ttcccattcc tcctttaagc tttttttaga acttgtaagt gctaaaaata
   111661 catcttcgag acttggctct acaatttcta ttgcatcaaa ttctatatca tgttctaaaa
   111721 gccatttatt tattaaagta aaagcagttc tactatcgtt tacacttata aaaattgaat
   111781 tttctcgtac gctcataaac tttactaaac cagtactttt aattgaatct ttatattttt
   111841 ttatatcttc agtattatga aaagttatac gtagtatatt ttgtctaatg taactacgta
   111901 aacttgatgg tgttccttgt gctaaatcct ttccattctt cataatacaa atattatcac
   111961 tcaattgttc agcttcttca agataatgag tagttagaaa tatagttgtg ccatactcat
   112021 ctctaatttt taataacata tcccacatag attttcttga atcgacatcc ataccaacag
   112081 ttggttcatc taaaaatagg attttaggag atgataccat attcatagct atgtccaatc
   112141 tacgttttac accccctgaa tatgatgaag taggatattt taagtaacta gataagtcaa
   112201 acttatcaat taaagagtct attctttgtt ttgcaatctg tggttctact ttatacattt
   112261 tactttgaaa taccatattt tccataaggg ataaatgttc atcaatagag atttgctgtg
   112321 ctacacaagc aatttgagta cgtatccaag aaggattatc tactaaatct tttccaaaca
   112381 ttgttacatt tccagatgta ggtttgtaaa aggtagtcaa aatatttata agagaagatt
   112441 taccagcacc attaggacca agtaaagaaa aaatttctcc agcatttaca ttaaagctta
   112501 gaccatttaa agctttcaca ccatttttat attcttttac taaattgtct atttcaatcg
   112561 ctaacatata ttattcctcc tctttaagtg gaaatattat ctctgtaata tagttatctg
   112621 ggtttccttt tatcaacata cctggtcctt taataaatac ttctctccaa ggagtttgta
   112681 tttttatatt attttcatga atatatttaa atatcatttc atacgttttt ggcaaattac
   112741 tataagagcc tgtgtgagta aaaaataaag cttttgtttt aggaaattct tttgtagtta
   112801 tacccatacg atttggagtt tcagcagttg gaacacataa ttccatttct gcaacaccag
   112861 ttttttggtc aacatcatag tagcaaaaga atggtgcacc gttagacttt ccttttatag
   112921 ctttaaatac atttggaaaa tactttgttg cctcagtcat aggtccatta taacgcatgg
   112981 tagccactgt gactgattcg atatttttga tttcaatttt gcaattcatt tgtttacctc
   113041 ctaatgtgtg ttcatattct tactagattt ttaagcatta atacatataa gattttgatt
   113101 agttgaaaac atataatctt atctcgtttg cttgttttca agtctaacat aacataaaat
   113161 atatatcctc tcatttgatg ctccattttg taaagttatt atttaagctt tactttagat
   113221 tttttagcaa attaaaataa agcaatttat aaaataagta tttacaaatt aagtgtatta
   113281 atcgtataat acacttaata ggatactaga taaagtctga aataaaggcg tattttttta
   113341 aagtaagtgt actatcgtat taatacacta gaataggagg aatcatgaat tttgaattag
   113401 ataatacaac tcccatttat ttgcaaatag taaagtatat aaagagacaa atagtaacag
   113461 gagagttgaa accaggagag acaataccat caagaagaga aatggcactt aatctaaaag
   113521 taaacttaaa tacagttcaa agagcatata aggagatggg tgatatgaat ataataaata
   113581 cttttaaaaa ttatcaaagc agtgtaacag ttgatgaaaa tatattaaaa aatttaaaat
   113641 tagagcttat aaatgaatca ctatctgttt ttatagaaga tatgaaagca ataaatgtta
   113701 gcaaagaaga agttttaaaa ataatagaag ataagtatta gttttttaac aaatagaaaa
   113761 cttagtttag aaagtttatt tataagcata ttggatgtgg aggatagtaa atatgataga
   113821 aataaagaat gtcagcaaaa catataaaag gatgcaaggg cttaaaataa gaaagataga
   113881 agctttaaaa aatgtaagtt ttaatataga aaagggaaaa ataactgcat tacttggtat
   113941 aaatggtgtt ggtaaatcaa ctatgttaaa agcaatagca ggacttataa acattgatag
   114001 tggagaaatt cgtatagatg gagaaaaaat aaatgaaaag gtatacaata aattggcttt
   114061 tgttccagat gtacaatctc actttagcaa tacaacaata aaagaaacat ttgaatttat
   114121 ggaaattttt tattcaaagt ggaataaaga aaaatcaaaa gaaatgatgg acatatttaa
   114181 attggatgaa gatgaaataa ttgataactt gtcaaaagga aacattgcaa gagtaaaatt
   114241 aatacttgga ttttgccaag acccagagta catacttctt gatgaaccat ttacaggaat
   114301 tgatttgttt aagagggaag agtttatagg agtaatagcg caatatatgg aggaaaatca
   114361 agccattatt ataactactc atgagatagt agagatagaa agtttagttg atgaggttgt
   114421 aattcttgat gaagggcaga ttataacttc atttaatgca gaagaattaa gagaaagaga
   114481 aggtaaatct atattagata agatgaggga ggtatataag aatgaataaa cttctatatc
   114541 taataaatgt agatttgaga agaagcaata agttttatat agcttatata tcattttttt
   114601 cattaattac acttagttta aatttattcg aaattaataa atttaaaaat tctaaattta
   114661 ttatgaactt agcaatagaa gattttggag gtatatttta tggactaggg atacttagta
   114721 atcttggttt tatccaaagt atattgttct ttgggatatt gggacttttt atatactata
   114781 tttttatgtg gaaaagagag ttcttttcaa ataatcaaag tatttataca cttatgatgt
   114841 tacctcaaaa taagtttaag atttgtatat ctaaatcaat agccttgata acaatgatat
   114901 atggtttttt gataagtcag acagcaacat tatttatatg taaatatata tttaatttca
   114961 tttttagaaa tatgcctata atcaatatga actttgccaa agatttatat tatttaaact
   115021 tgaagagtat accaattgat tttatctctt ttatggctat ttatgtattt ttactactta
   115081 tagctatttc tattgtaaat tgctgtatat tatttatctt ttcctatata aataaatttt
   115141 atgtaatttt aatcactttg ctgattatag caggcttata tttttcaaca atatatataa
   115201 atataatcac tttatttaga aaatattata atcttatagg atttcaattt aacaatttag
   115261 tagcagggtt attaagtttt ttaattataa tgtttattct aaatggaata tcttatttgc
   115321 taattaaaaa gaaagtatct ctttaaggag gggtggtatg aaattaaaat ctaaaatatc
   115381 tatatttatt atatttttga ctttagcaat atattttagt ataggtttat taaataatga
   115441 agataattta aagataaaaa ctataaaagg tgactctaat gaattagacc atataaacat
   115501 aaattttgga tatgctttga atggatatat aaattcatat tatacaataa atggaagcaa
   115561 caaaaccaaa aagactgaat taataaaact acaaaaggat agtaagaaca caaataattt
   115621 aattgatgta tctagtggtt cagatttaat tgctcatgtt ggatttgaaa tgaatgagga
   115681 gtcaaaagat ataaactttg tgatagatga gaaaaaagaa gatttagaaa aaggtgtatt
   115741 tccatcagaa ggtagtgata aagaaattga atatgaaaaa ttagatatga ataattttac
   115801 aaggacaaga tataaagtag ataaaagtac agatgattat tatgcaaaga tactagcatc
   115861 aaaaagatat aaaaaatact tatatgtatc tgtactttat gctacaagtg attcatcaga
   115921 aaataacaaa gaatattcaa gtactataga tataataaaa attaatccag aaaataaaaa
   115981 aatcaagact ataaaaagta taaatttaag taattatttt tccgaaaaat accaaaacat
   116041 agagaacata ggtgtaagtt atgctagcaa atatgaggat aagatgtata ttttagtaaa
   116101 tgtactaaat acaaacatag gtgataatag taattctaaa tttcatttac ttgagtataa
   116161 tcttgaagaa aataaggaaa gcataatgga attaaaaact gatagcaaaa tggctttagc
   116221 aaaagcaaag ttagaagcta ataaattata tatggtaatg tcgaatgatt atgataatag
   116281 ttcaattaca gagttaaatt tacttaccta taatatatta gataaaagct tagatgaaga
   116341 taaatatgtt ttagataata gagaaaaaag aggaattaga agtattgaaa ttgattcaaa
   116401 taaaatcgtt gcatatacat caaggctaaa ctctatatta tcttgggatg ataaatttat
   116461 gctatatata ataaataaaa attctaagga aattgtatat gaaggagaat tacaatttaa
   116521 cagttcaaat agtatgttag aatttgaaat aaagtaggtg agttgatgaa agatttaata
   116581 agattattcg aatttgaatt aaaaagaaat ataaagaatt atatatttat aataatttgt
   116641 tgttgttctt ttgtaatttt aaacatagta aaaaatttaa atgactataa ttacataata
   116701 gaaaatgcag ttaaaagtga acagttaaca aaaatcggaa atacgataga aacggtaaat
   116761 gttacaggtt tctcaagctt tagaaatata atgggttcta cagaatcgtg gtttatgttt
   116821 ggtataattg catgtatttg ctatgctttt tttatttggt atagagactt taatggtaga
   116881 agtaaatcta tatatacact tataatgcta cctaaaaata gaatcaatat ttatatatct
   116941 aaattattaa atatattatt tctagtgtat agctatacag tagtacttac aatatctttg
   117001 tttattgcaa gtaagttgtt gcctagacat atgcttggta atgtcacaaa ctatggtttt
   117061 gtacaagaaa caatatatga gttaaaaatg ttacttccat atagctttga aatactattt
   117121 gtagagtata tatttttatt gataggattt gtatctgtag tatttacatc aattcttata
   117181 aataaatcta tttataaagt aagcacttta ataagttttc tatttttagt tatagaaatt
   117241 ttagtgttta taatttctat agaatttatt ataccttacg aatacagtga tgtatttact
   117301 gttctatatt caagtataaa catatttgta tgtagtctta tatctaataa acttttgaag
   117361 caaaagattg acttttagga gggatattat gaaagcaaaa aatataggaa aatatacaat
   117421 atgttttata atagtatgtt ttttaatgat tactatgacc ttaatattga gttattttaa
   117481 taaggataaa ctatctgtaa aaactttaaa aggcaatgta aaagatatag ggagagtaag
   117541 tgtagtatat acacctaata taagcaaatt ttcttatgag gaggtaatta taagtaaaaa
   117601 tggagtaaga aataatacaa acccaaaatc aagaattaga aatgattatt taaatattga
   117661 caaaaaatac agtgactttg ttaatgataa aggaaaagaa tttatatata aagatgattt
   117721 gaatatagga gaagcgtata cctctgttaa gtctgattta gtacaaggaa tgaatgcttt
   117781 aaatgattgt ataaaggttt caaataaaaa tttaaaaagt ggggtagaag aaaattttga
   117841 tattaattta aataagtctg attttaaaga aaatagttgg aaaaccttat ttaacaaaat
   117901 atataaaggt aatttatata tggtaattag tgaaactaat atttca
//
LOCUS       DAEQAF010000003        94000 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.003, whole genome shotgun sequence.
ACCESSION   DAEQAF010000003 DAEQAF010000000
VERSION     DAEQAF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 94000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 94000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..94000
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.003"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            20..403
                     /locus_tag="KRN00_000263"
     CDS             20..403
                     /locus_tag="KRN00_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826158.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            911..1294
                     /locus_tag="KRN00_000264"
     CDS             911..1294
                     /locus_tag="KRN00_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1826159.1"
                     /translation="MNLTKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDTSQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            1296..1646
                     /locus_tag="KRN00_000265"
     CDS             1296..1646
                     /locus_tag="KRN00_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826160.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(1747..2205)
                     /locus_tag="KRN00_000266"
     CDS             complement(1747..2205)
                     /locus_tag="KRN00_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826161.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYAPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLNEVYINQSRASYRSGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(2250..3038)
                     /locus_tag="KRN00_000267"
     CDS             complement(2250..3038)
                     /locus_tag="KRN00_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1826162.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(3177..3614)
                     /locus_tag="KRN00_000268"
     CDS             complement(3177..3614)
                     /locus_tag="KRN00_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH1826163.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            4436..4945
                     /locus_tag="KRN00_000269"
     CDS             4436..4945
                     /locus_tag="KRN00_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1826164.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVESEVDNLKVISEKLEIINLQLAQRKNMRRKMFHWLF
                     ILLCAVILIVFVVLGRLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFLTRKKI"
     gene            5350..5886
                     /locus_tag="KRN00_000270"
     CDS             5350..5886
                     /locus_tag="KRN00_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH1826165.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKR"
     gene            complement(6327..7127)
                     /locus_tag="KRN00_000271"
     CDS             complement(6327..7127)
                     /locus_tag="KRN00_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826166.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLLYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(7322..8920)
                     /locus_tag="KRN00_000272"
     CDS             complement(7322..8920)
                     /locus_tag="KRN00_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1826167.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINILESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            9248..9424
                     /locus_tag="KRN00_000273"
     CDS             9248..9424
                     /locus_tag="KRN00_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826168.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            9598..10728
                     /locus_tag="KRN00_000274"
     CDS             9598..10728
                     /locus_tag="KRN00_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1826169.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVAGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            10969..11319
                     /locus_tag="KRN00_000275"
     CDS             10969..11319
                     /locus_tag="KRN00_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH1826170.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            11327..11776
                     /locus_tag="KRN00_000276"
     CDS             11327..11776
                     /locus_tag="KRN00_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBH1826171.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLGKYKNIDEV"
     gene            11878..12453
                     /locus_tag="KRN00_000277"
     CDS             11878..12453
                     /locus_tag="KRN00_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1826172.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENLAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            12446..13855
                     /locus_tag="KRN00_000278"
     CDS             12446..13855
                     /locus_tag="KRN00_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBH1826173.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            14039..15472
                     /gene="eutA"
                     /locus_tag="KRN00_000279"
     CDS             14039..15472
                     /gene="eutA"
                     /locus_tag="KRN00_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBH1826174.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            15490..16854
                     /locus_tag="KRN00_000280"
     CDS             15490..16854
                     /locus_tag="KRN00_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBH1826175.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            16867..17748
                     /gene="eutC"
                     /locus_tag="KRN00_000281"
     CDS             16867..17748
                     /gene="eutC"
                     /locus_tag="KRN00_000281"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBH1826176.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            17768..18421
                     /gene="eutL"
                     /locus_tag="KRN00_000282"
     CDS             17768..18421
                     /gene="eutL"
                     /locus_tag="KRN00_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBH1826177.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            18432..19133
                     /locus_tag="KRN00_000283"
     CDS             18432..19133
                     /locus_tag="KRN00_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH1826178.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDNSLTEA
                     NEEKIENTNDKEVLEQVKIENFDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            19136..20605
                     /locus_tag="KRN00_000284"
     CDS             19136..20605
                     /locus_tag="KRN00_000284"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBH1826179.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISE
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     MPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            20701..20988
                     /gene="eutM"
                     /locus_tag="KRN00_000285"
     CDS             20701..20988
                     /gene="eutM"
                     /locus_tag="KRN00_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBH1826180.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            21115..21876
                     /locus_tag="KRN00_000286"
     CDS             21115..21876
                     /locus_tag="KRN00_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBH1826181.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVFKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            21889..22518
                     /locus_tag="KRN00_000287"
     CDS             21889..22518
                     /locus_tag="KRN00_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH1826182.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     GYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRPLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            22560..23285
                     /locus_tag="KRN00_000288"
     CDS             22560..23285
                     /locus_tag="KRN00_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBH1826183.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKEDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            23298..23570
                     /locus_tag="KRN00_000289"
     CDS             23298..23570
                     /locus_tag="KRN00_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBH1826184.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            23563..24114
                     /locus_tag="KRN00_000290"
     CDS             23563..24114
                     /locus_tag="KRN00_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBH1826185.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            24126..25217
                     /gene="eutH"
                     /locus_tag="KRN00_000291"
     CDS             24126..25217
                     /gene="eutH"
                     /locus_tag="KRN00_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH1826186.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            25219..25692
                     /locus_tag="KRN00_000292"
     CDS             25219..25692
                     /locus_tag="KRN00_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBH1826187.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(25812..25913)
                     /locus_tag="KRN00_000293"
                     /pseudo
     CDS             complement(25812..25913)
                     /locus_tag="KRN00_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            26208..26729
                     /locus_tag="KRN00_000294"
     CDS             26208..26729
                     /locus_tag="KRN00_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1826188.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            27108..28283
                     /locus_tag="KRN00_000295"
     CDS             27108..28283
                     /locus_tag="KRN00_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1826189.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLVFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            28317..29855
                     /locus_tag="KRN00_000296"
     CDS             28317..29855
                     /locus_tag="KRN00_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1826190.1"
                     /translation="MQGALKENKKKSGGGFLGWIEKVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQDFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQVI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            29887..31089
                     /locus_tag="KRN00_000297"
     CDS             29887..31089
                     /locus_tag="KRN00_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1826191.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKDENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWINQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(31255..31854)
                     /locus_tag="KRN00_000298"
     CDS             complement(31255..31854)
                     /locus_tag="KRN00_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1826192.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARCIKVQL"
     gene            32024..33382
                     /locus_tag="KRN00_000299"
     CDS             32024..33382
                     /locus_tag="KRN00_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826193.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDKQFNILNI
                     KFVKLFDKYDNQDNINKEILFDIKESSKNIYNATESQFKIRDYIKNINAGFALYERSA
                     QDLLTKLMTHENKISQNQKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSL
                     DIQDKLDVMFNNSFMNDEVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDEL
                     NE"
     gene            33375..34007
                     /locus_tag="KRN00_000300"
     CDS             33375..34007
                     /locus_tag="KRN00_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1826194.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            34336..35493
                     /locus_tag="KRN00_000301"
     CDS             34336..35493
                     /locus_tag="KRN00_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1826195.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(35640..36275)
                     /gene="lexA"
                     /locus_tag="KRN00_000302"
     CDS             complement(35640..36275)
                     /gene="lexA"
                     /locus_tag="KRN00_000302"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBH1826196.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(36379..37506)
                     /locus_tag="KRN00_000303"
     CDS             complement(36379..37506)
                     /locus_tag="KRN00_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1826197.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(37828..38673)
                     /locus_tag="KRN00_000304"
     CDS             complement(37828..38673)
                     /locus_tag="KRN00_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826198.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFFHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(38703..39074)
                     /locus_tag="KRN00_000305"
     CDS             complement(38703..39074)
                     /locus_tag="KRN00_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1826199.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(39227..39487)
                     /locus_tag="KRN00_000306"
     CDS             complement(39227..39487)
                     /locus_tag="KRN00_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBH1826200.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(39676..40620)
                     /locus_tag="KRN00_000307"
     CDS             complement(39676..40620)
                     /locus_tag="KRN00_000307"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBH1826201.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(40641..41495)
                     /locus_tag="KRN00_000308"
     CDS             complement(40641..41495)
                     /locus_tag="KRN00_000308"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBH1826202.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(41510..42871)
                     /gene="accC"
                     /locus_tag="KRN00_000309"
     CDS             complement(41510..42871)
                     /gene="accC"
                     /locus_tag="KRN00_000309"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBH1826203.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(42887..43339)
                     /gene="accB"
                     /locus_tag="KRN00_000310"
     CDS             complement(42887..43339)
                     /gene="accB"
                     /locus_tag="KRN00_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBH1826204.1"
                     /translation="MNINEIKELLEAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(43609..44055)
                     /locus_tag="KRN00_000311"
     CDS             complement(43609..44055)
                     /locus_tag="KRN00_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826205.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            44330..44608
                     /locus_tag="KRN00_000312"
     CDS             44330..44608
                     /locus_tag="KRN00_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826206.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     ILVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(44737..45483)
                     /locus_tag="KRN00_000313"
     CDS             complement(44737..45483)
                     /locus_tag="KRN00_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826207.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGQAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(45612..46256)
                     /gene="trmB"
                     /locus_tag="KRN00_000314"
     CDS             complement(45612..46256)
                     /gene="trmB"
                     /locus_tag="KRN00_000314"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBH1826208.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(46394..46714)
                     /locus_tag="KRN00_000315"
     CDS             complement(46394..46714)
                     /locus_tag="KRN00_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBH1826209.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(47167..47415)
                     /locus_tag="KRN00_000316"
     CDS             complement(47167..47415)
                     /locus_tag="KRN00_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1826210.1"
                     /translation="MQKTKAWGIIEPEKPESQQQMAHMDFAVKDLEEAVQYAIHCGAT
                     IAEEQFTDDWRVMIDPAGHPFCLCQMKSIMESSHFSLL"
     gene            complement(47446..47907)
                     /locus_tag="KRN00_000317"
     CDS             complement(47446..47907)
                     /locus_tag="KRN00_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH1826211.1"
                     /translation="MKFGGVLLIVKDINKSKKFYEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFITQFQQV"
     gene            complement(47945..48778)
                     /locus_tag="KRN00_000318"
     CDS             complement(47945..48778)
                     /locus_tag="KRN00_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826212.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(49053..49739)
                     /locus_tag="KRN00_000319"
     CDS             complement(49053..49739)
                     /locus_tag="KRN00_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826213.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(49754..52231)
                     /locus_tag="KRN00_000320"
     CDS             complement(49754..52231)
                     /locus_tag="KRN00_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1826214.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNAIKSKVGVLESSAIYNKGVYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRISPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKAYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIEAFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIVGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(52450..53853)
                     /locus_tag="KRN00_000321"
     CDS             complement(52450..53853)
                     /locus_tag="KRN00_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1826215.1"
                     /translation="MHKPSYKTVFHSYIIFFMIFICLILTVIGIFLSLITIQKPNGEF
                     IRSDWPKKFTENFNEQIVFIDNKPQVKQSGLKKLRENQLWLQILDSSGNRVYGFLEPK
                     EHKDYYSNSELLALANQNNSSNGTVYFNTIKNNKNDYIYIIYFPLNISKVNMFFDGGK
                     FIGGKSIVFSIIGIIFLIILVSGIAYGYWVTKCISNITSAVSDISKRSYLPVNIKGVF
                     ADIYNSLNILNEEIHKSDEIQNKTDIMREEWISNITHDLKTPLSPIKGYAELLTDSST
                     NYSPEKVYKYASIMLKNIEYTNTLINDLKLTYQLKNGIIPLNKNNYDLVRFLKELSID
                     ILNYPEYESNIVEFKSNIDNINFDFDCTLLKRAFSNLIVNAFTYGDKNTKVCVHITLN
                     ERIEIIISDNGKGMSREEASNLFNRYYRGSNTKQKIEGTGLGLAITKQIIEVHGGNIS
                     VESIPGLGSSFYITFPI"
     gene            54346..55206
                     /locus_tag="KRN00_000322"
     CDS             54346..55206
                     /locus_tag="KRN00_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1826216.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(55445..56002)
                     /locus_tag="KRN00_000323"
     CDS             complement(55445..56002)
                     /locus_tag="KRN00_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1826217.1"
                     /translation="MSDSEYPQMKTLETRSCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(56192..57079)
                     /locus_tag="KRN00_000324"
     CDS             complement(56192..57079)
                     /locus_tag="KRN00_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1826218.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            57198..58397
                     /locus_tag="KRN00_000325"
     CDS             57198..58397
                     /locus_tag="KRN00_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBH1826219.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(58591..61146)
                     /locus_tag="KRN00_000326"
     CDS             complement(58591..61146)
                     /locus_tag="KRN00_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1826220.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWPLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKN
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRSMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(61143..61829)
                     /locus_tag="KRN00_000327"
     CDS             complement(61143..61829)
                     /locus_tag="KRN00_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826221.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     IVVNTGGEVL"
     gene            complement(61906..62814)
                     /locus_tag="KRN00_000328"
     CDS             complement(61906..62814)
                     /locus_tag="KRN00_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1826222.1"
                     /translation="MFILAFIICTVVIFIVSTKINQKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(62816..63487)
                     /locus_tag="KRN00_000329"
     CDS             complement(62816..63487)
                     /locus_tag="KRN00_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826223.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKKCLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            63749..64813
                     /locus_tag="KRN00_000330"
     CDS             63749..64813
                     /locus_tag="KRN00_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBH1826224.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            64971..65657
                     /locus_tag="KRN00_000331"
     CDS             64971..65657
                     /locus_tag="KRN00_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826225.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKGNYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            65647..66678
                     /locus_tag="KRN00_000332"
     CDS             65647..66678
                     /locus_tag="KRN00_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1826226.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITGDLKLIALLL
                     IYTMVLCGFIALIIFLLHKKIVIFCYKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMIKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNALKYTNSNGKIRVATECWVMYTKIDII
                     DNGKGISESHQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            66760..67425
                     /locus_tag="KRN00_000333"
     CDS             66760..67425
                     /locus_tag="KRN00_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826227.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            67438..69855
                     /locus_tag="KRN00_000334"
     CDS             67438..69855
                     /locus_tag="KRN00_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826228.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDELRPDTVDVLV
                     KLSEENTEKDSASIKTQLNKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLKKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     SYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRTFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(70036..70827)
                     /locus_tag="KRN00_000335"
     CDS             complement(70036..70827)
                     /locus_tag="KRN00_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1826229.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFYKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(70860..71447)
                     /locus_tag="KRN00_000336"
     CDS             complement(70860..71447)
                     /locus_tag="KRN00_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1826230.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(71624..73015)
                     /locus_tag="KRN00_000337"
     CDS             complement(71624..73015)
                     /locus_tag="KRN00_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HBH1826231.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSKEIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVITAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(73205..74503)
                     /locus_tag="KRN00_000338"
     CDS             complement(73205..74503)
                     /locus_tag="KRN00_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBH1826232.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIMNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLKALEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFELWNRTIEFYKKPLSSDLNN"
     gene            complement(74862..75737)
                     /locus_tag="KRN00_000339"
     CDS             complement(74862..75737)
                     /locus_tag="KRN00_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBH1826233.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(75930..76616)
                     /locus_tag="KRN00_000340"
     CDS             complement(75930..76616)
                     /locus_tag="KRN00_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBH1826234.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(76665..77198)
                     /locus_tag="KRN00_000341"
     CDS             complement(76665..77198)
                     /locus_tag="KRN00_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH1826235.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(77242..77874)
                     /locus_tag="KRN00_000342"
     CDS             complement(77242..77874)
                     /locus_tag="KRN00_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBH1826236.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(77964..79043)
                     /locus_tag="KRN00_000343"
     CDS             complement(77964..79043)
                     /locus_tag="KRN00_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBH1826237.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(79176..80522)
                     /gene="pepV"
                     /locus_tag="KRN00_000344"
     CDS             complement(79176..80522)
                     /gene="pepV"
                     /locus_tag="KRN00_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBH1826238.1"
                     /translation="MKDQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELDKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(80591..81871)
                     /locus_tag="KRN00_000345"
     CDS             complement(80591..81871)
                     /locus_tag="KRN00_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBH1826239.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEDIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(81998..82258)
                     /gene="hfq"
                     /locus_tag="KRN00_000346"
     CDS             complement(81998..82258)
                     /gene="hfq"
                     /locus_tag="KRN00_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBH1826240.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(82372..83307)
                     /gene="miaA"
                     /locus_tag="KRN00_000347"
     CDS             complement(82372..83307)
                     /gene="miaA"
                     /locus_tag="KRN00_000347"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBH1826241.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINEKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(83345..85312)
                     /gene="mutL"
                     /locus_tag="KRN00_000348"
     CDS             complement(83345..85312)
                     /gene="mutL"
                     /locus_tag="KRN00_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBH1826242.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYSCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(85323..88166)
                     /gene="mutS"
                     /locus_tag="KRN00_000349"
     CDS             complement(85323..88166)
                     /gene="mutS"
                     /locus_tag="KRN00_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBH1826243.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIEKLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALMKQNDDKEKINQEDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(88327..89061)
                     /locus_tag="KRN00_000350"
     CDS             complement(88327..89061)
                     /locus_tag="KRN00_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826244.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIKVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(89030..90043)
                     /locus_tag="KRN00_000351"
     CDS             complement(89030..90043)
                     /locus_tag="KRN00_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1826245.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(90065..90835)
                     /locus_tag="KRN00_000352"
     CDS             complement(90065..90835)
                     /locus_tag="KRN00_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826246.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(90810..91100)
                     /locus_tag="KRN00_000353"
     CDS             complement(90810..91100)
                     /locus_tag="KRN00_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBH1826247.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(91231..91330)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      91950..92039
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            92092..92268
                     /locus_tag="KRN00_000354"
     CDS             92092..92268
                     /locus_tag="KRN00_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826248.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(92383..92739)
                     /locus_tag="KRN00_000355"
     CDS             complement(92383..92739)
                     /locus_tag="KRN00_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826249.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSVGFTMTVIGSKWREIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLEIDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            92995..93908
                     /locus_tag="KRN00_000356"
                     /pseudo
     CDS             92995..93908
                     /locus_tag="KRN00_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007061260.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
BASE COUNT        33893 a        13521 c        12561 g        34025 t
ORIGIN      
        1 agaaaggaat gtgctttata tgtctacaga caaagttgtt ggaatcatag atgaagaaac
       61 ggcagaactt gcaggaattg aatatactgg taaaatttat gcttcttctg gtgttataaa
      121 acatataaag aaaaaacata gatgtcaact gagtaaggat atttttaatg atataataga
      181 cactataaaa atggtattaa agtcacctga atatatagga agtcatccta aaaaacctgg
      241 aaaaagtgtg gagtttataa aaaaaattga tgattatatt ttagtagcta cagaattaga
      301 tacaaaaaaa ggatatttat atgtatcttc aatgtatgct ataaaagaag caaaattaga
      361 aagtagagta aacagtggaa gagtaaaaca atatgatggt taacataata ttattaattt
      421 tccctaaaat attgaaaaat attattatat aagttataat attaatatac acgtagatat
      481 ttattagtta gatttgaggt tggaaaaggc acccaatacg ctactataga gtagttaata
      541 gagatgcagg atacgccgcc ctgccaaatc taattaaatt aaaaagagag gattaattcc
      601 tctcttattg tttttttgag atactaattt aatctataat agaaagattg aaggtcgttt
      661 atacaaaaaa attttcagtt atatacatta aactaattaa ataagatatt tataatctat
      721 atgtgataca tattatatat taataaaaga aaaatatata gaaaatcctt ataaaaattt
      781 aaattgtaat gaataggaag taattaaaaa gaatttttat tgatttttaa aaatttagtt
      841 agaaactata tcattatggt aaaaaatgta ttataatgtt tagaaatatt ataataagga
      901 gcgattaaac atgaatctaa cgaagaaaat agaagataaa agaaaagcta aacagagagc
      961 tgaaaaagtt aagaaagcta aaattgctac agctggtgtg gtattaggag ctgttactgg
     1021 tgcagtgagt ggagtacttt tggctcctaa atctggaaaa gaaacaagag aggatataaa
     1081 agatacttca caacaaattg ctgaaaagat aaatatgaaa actgtagatg taaaaggcaa
     1141 agtatctgag aagctagagg ataaaaaagg aaactttata gaatcaaaga aaaaaataaa
     1201 aaaatatata gataacaaaa agagtgttga aaattctagt gaggaagata aaataataga
     1261 tatagttgaa ccagttagtg ttactgagga ataatatgga caatacaata acgattaaca
     1321 taagtataat atatgtatta ttagctatac ttgcttgtat tgctttagtt tatttaatta
     1381 ttgtacttgt taaactacat aagattttaa ataatgttgg aactatgtta aatgaaaata
     1441 ctcaaaatat aaatacaact ttaaataatc ttcctaatgt tgtagaaact tttggagaag
     1501 taggagaaaa tatgaaagat gtaacagaag tagttactga agttacagca gattttcttg
     1561 ttactaaaga cagtgtcaaa tcaaatatgg atgttatagt tgatatattg actataatta
     1621 aaaacatttt tctagataaa aaataataag ttaatataaa ataagcctat aagatataat
     1681 ttaaacgacc ttaaaatagc atttataagg tcgtttttta ttagcttgat ttgacactat
     1741 gtgtttttaa taattggtaa tattcctctt tatcatttga acatatatat ctatgcttgt
     1801 tgtttcaatt acatccataa gaacatcttt acattcaagc tcaaaatctt ccattccttc
     1861 taaatattca tcatcttcat caaaaaagat ataagaatta tatagccatt cttcaaattt
     1921 ttcttcaagt atatcccaat acgaactcca aaataatcca caacctgatc tataagatgc
     1981 tctactttga tttatataaa cctcatttag aagcttttgt aatctactgc tataaagaaa
     2041 atctgctctt ccactgcttg atattaattc atttaaatct tctattgaca ttaattcaac
     2101 tttaccactt ttatcataag gagcataatt ttcatcaacc catttatgtg gtttgttttc
     2161 tctgcatact gttgctatca actctacaac ttttgttctt atcatttttt tatcctaact
     2221 tatttatttt ttataaaata atcatgattt tataatttat ctatttcttg taatgctaat
     2281 ttaacagttt catatctatc agcaccattt attactacat caccttttac aagtttatta
     2341 gcttctccac ctacaacata aaccttttta cctaaacctt gcttataact agacgcctca
     2401 attattaaag aatctttcaa ttgccaatgt aaaatctgag cagccacttt atcagcatca
     2461 cctgtataaa cgattacatt ttcatacact ttattttccc ctcccccttg agaatttgat
     2521 atagatttgt ttagtatacc ttctgctatc aatttagcaa ctttatcttt attattaaca
     2581 taataatctg tatctgcttt actatctaca aaacatactt ctattaatat tgctggtgca
     2641 atagtatgat taagccaata aagacctcta acatcagact ttgcacccct atctttgaat
     2701 actgtagcta acctagtatt cactctttct gcataggttt tgccattatt agtcttatat
     2761 attgtttctg tccctactgg agttgaagtt gtagcatttg aattaaaatg aatctgaaca
     2821 gccaaatcag tttcctgttt atttgctata gcacattggt ctgctaaatg attacttgat
     2881 tcatcaactc ttcctgtata aacagtagct ccacctattt taagccattt aacaattaag
     2941 tcattcagta ttcttgtttc tttgctttcg tttatatacc caacagctcc tgtacctttt
     3001 ccaattaaag tgtgccctgg tattattact actttcaaac taacatctcc tttacaatta
     3061 aatttaactt ctatttaata tatgcataac ctagaatttt gtttcttttt atatcttata
     3121 cttttattat aacccatttt gtaaaaatat agaatattaa gtaaataatg ttaaaattat
     3181 aattttgtat ataagacatt acttgattgc aataatttta tagcatattc atctattcta
     3241 tatccagttc tataatatat atgtttaatt ccagcttgaa ttatagcctt agtacaattt
     3301 aagcaaggaa agtgagttac ataaatagag caatctttaa ctgaaatacc ttcttttgca
     3361 caataataaa gggcattttg ttcagcgtga atggttctaa tacaatgtcc atctctcatt
     3421 tcatgaccaa cttcactaca atgcttatct ccagaaatac taccattata tccagtagac
     3481 actattctgt tttctgaatt gacaattata gctcctacat aagctctatc acaagttcct
     3541 ctttcagcta ctgtttcgca cagtctcata aaatattctt gccatgagca tctattttca
     3601 agttttttat tcaaatcata tacctccaaa atttatatct aatatataag atttatacct
     3661 taaaaataat attaaaaaca aatttatacg ataaataaaa tttattaata ctgtttttag
     3721 tctaaattat ttcattttaa attaaagtta caaggaatct aaaattatat atatctttct
     3781 tcgtaatatg aatgttacaa tataaaaaac tgtctcaata aaatagagac agttttacag
     3841 tcaaagttta taatacaagt tcatattttt ctttaaattc ttttacagct tcgggccatg
     3901 ccttttgttc tgtaatacct ttttctttag ctattttaat tgcaatctct cttatcattg
     3961 cagcgccttc taatattccc atttttaatc tcccttcaaa tatctttttg tatagaatat
     4021 aaatagtgct aagatttatt acatgctgca tatacaatat ctatacaaca cataacttgt
     4081 aaattccttt tattttcata cgtctttaac cgacatataa ttatattcaa taagttttaa
     4141 aattatgaac tcaattataa ttatttttat ttttttagaa tctaaacact aaaaattgta
     4201 ggtaaatttg tcttatgcct ttataaatat ttctacagtt ttaattactg gacatatcta
     4261 tttttattat aaaaagcgat taaaaatgga gaatatcctc ataaaaacta tatataagca
     4321 aaacggttaa aggaaaaaga agaaatttac ttgaatgtta aaatgcgttg cttgaagcaa
     4381 tgggcagttt tgcctataat atcggtaaca actgaaagaa aggtggttag ccctaatgtt
     4441 aagcgaaaac attaaaacaa tcaggaagtc aaaaggactt tcacaacaag aacttgctat
     4501 aaaactgaat gtagtgcgac aaacaatatc taaatgggaa caaggactgt cggttcccga
     4561 ttctgatatg ttgatttcca tatcagaggt gcttgaaacg cccgtaagca ctttacttgg
     4621 agaaactatt gttgagtcgg aagttgataa cttaaaagtg atttctgaaa aattagagat
     4681 tataaacttg caacttgcac aaagaaaaaa catgagaaga aaaatgtttc attggttatt
     4741 tattttatta tgtgcagtca tattaatagt ttttgtggtc ttagggagac taaatagtcc
     4801 ttacttggat tggaattata ccgaccctga aaccgctgtt tttggagtag cttttcatgc
     4861 ttttgagtgg ctatttgtca gattagtacc gattgtcctt ataggagcaa ttattggaat
     4921 ctttttgaca cgtaagaaaa tatgaagtaa ctctgctttt tataatacag caagcgttcc
     4981 ttaaaagcgt cattctacat ggcaatcgag gacgactatg taaggaagaa ccttttggat
     5041 ttccaactaa gcgaagttat tgaggacgac agtaggccca aaaccgcatt aagtaaagta
     5101 caggaagcaa gactgctgga cttatactct catgcgtaag atgcaggaaa tgcgaggtct
     5161 ggtagcatga tttacaacga tttgtacaac gactacgagt agaaatatat ggagataagt
     5221 attatctacg aaatcagaaa agaaatgact tgataattta ctcatgttat aattattgat
     5281 gtgaaattaa taaatcgaaa ttcctttttt ggatttaaca atactgagta aggaaaaagt
     5341 gaatgacttt tgcaaggagg tgttaatatc aggcaagtaa agtcttttgt ttttccagtt
     5401 atatccttaa tattcttaga ccaaattagc aaagttctta taggattatt cttaatggac
     5461 tttgaaattg atataattgg gaaattttta agattcaatc ctgttcaaaa tacaaatctc
     5521 tcttatgggg gaaactttat tggtattcta tctaatttat gggtattggt attgtttaac
     5581 attttagtta tattagttat tatatctgga tatgcttttt ataaatcaaa aaatgaacaa
     5641 acaagctatt cagtaaaagt aattatgtct tgtggacttg ctggtacaat atgtagcttg
     5701 atagataaat tattttgggg aggaagttta gattttttgc agataccaag cttttttatt
     5761 ttcgacttaa aagactgcta ccttactgtt gcagaaataa tatttgttgt cataggaatt
     5821 ttgcataata gagaaatatc aatgaaagaa tacatatatt tttgctatcg tcagtttaaa
     5881 agataaattt agaagataaa tttaagtttc aaggtaaact tatttaatca cagcaaatag
     5941 ttggcttact taagcttttg ggctaaactg tgagcactaa ttaagtctct gctatctaac
     6001 aaacggagca caaaaataaa aataaaaatt aaatattaaa tataaagcac agttaatttt
     6061 gattaaaaag ttgactgtct tttcttttgt agaaatttaa gcataggtaa taaagaaatg
     6121 actgcattta agcattatgt atataattgg aggcaataaa aagccagcaa agcccataaa
     6181 atagagctgt gctagcaaca tgatgagtta taagaagata atcaaaaaac ttacgcttta
     6241 ttttaattta aaaaaatgat tactgtaaag aaatcatttt ttattataat cactgataca
     6301 tcaaatattc taaataaaat ttttatttat ctggaattgt atattttttc tataatatta
     6361 actacagcgt acattgccca agcacagata gccaatacaa atactcccat cattactaaa
     6421 tctaatttaa atacttgaga accatatact atcaagtagc ctattccata tcttgaaact
     6481 aaaaattctc caactattac acctacccat gccataccaa tattaatttt agttaaattt
     6541 attaaatttc ctgtgtttgc aggtaatatg agtttaaata atatttgaga tttagtagct
     6601 ccaaagcttt ttaacatctt aattttttct tcatctatat tcataaaata attataagct
     6661 gaaagtatag taacaacaac agaaatcgtt acagctgtta cgacgattcc ttctattcca
     6721 gcacctaccc aaactataat tataggagct aaagcagtct taggaagagc atttaaaact
     6781 accaaaaatg ggtctaatat ttttgataat ttttctgacc accaaagagc aattgctacc
     6841 aaaataccta atacagtacc tataacaaga ccaagaacag tttcatatac agatattcca
     6901 atatgtttaa ataattgacc actaaatgca tattgaataa ataaattgta aatatcactt
     6961 ggtttgctaa atagaaatgt atttataaca tttaagtcag ctaaaagttc ccagattaca
     7021 ataaaaccaa ttaaaattaa tagctggtat aataatacat ttcttttttc tctttttaca
     7081 cctttaacat agtttatata tccttcagat cttttattaa gcctcatgtg tatctagctc
     7141 cttccataat atgtcgaaat acttttgaaa atcaggaact ttacgtgttt tgagaggcgt
     7201 ttttgttcca tccatgttaa gttcaatatc gtaaatattt tttatggtag ctggtctttt
     7261 agatagtatt gcaaccttat ctgatatgct tattgcttct gctatagcta aaaaagtgca
     7321 actaattgct taaagaaaca gaattatcaa cttcagcacc catataaaca atattaagat
     7381 ttcctaaact gctatcccaa acgatactat taataatagt agataataac aatctcttat
     7441 catctaaact ggcattatca acttcatcat taaatctctt caaattacta acaataatat
     7501 caatattaat actgtcacta ctaatattga tgttactaga ttccaaaata ttaatcttat
     7561 cctttaaaat actaatctca ttatttaggc tctcaatctg ggaaactata taatcagaag
     7621 cagtactacc agtatttttt gcaagctcta taactaaatt tttaataagt ctttccttat
     7681 ctaaaatttg atttttaagt aaattagtct cagatttaaa aatattaaaa acattatcag
     7741 tcttaatgtt attactattg aatgcactta taatagactc ttctttacaa ttcttaattt
     7801 tatctataac taaactttca actaatggac cattaaggtt tttacagttg caactatcag
     7861 acccaagtgt ttttttagta ccacaaatat aataatactt taaatccttg tcagtttttt
     7921 tgcctttata ggtaattctc atattagaac cacatttacc acattttata agaccagata
     7981 aaagagcagt ttttccagtt gatatccttg gagttttatc acgattttta tctaattgat
     8041 tttgtacttc aagccatatt tcaggttcta tgactccatg gtgttttgca attgctgcta
     8101 ttgagttaga tgtattttta gcataagtaa ggattccaca ttttctatct ggagtaccta
     8161 caacatccat accactattt ttaaggtaat ctaaaatttc atcattagct tttacatatg
     8221 ctggatttct aagtattcta gataaagaac tagggtcaaa tttaccacca cgaggacccc
     8281 ttattccatt attatagaca tatttatata acttagataa ggacctaagt tctaaatatt
     8341 tattgtatat tagctttaca atctccattt gttcatcatt tacttgaagc ttatacatac
     8401 ttctttcttt tagattttca tctaagaatg tgattttttc actgttgaat ccatgaggtg
     8461 tattgcctcc aagccatcta ccactacggg ctaattcata catattgtct tttatacgtt
     8521 ctgctattgt ttctctttct aattgagcaa atacacttga tataaacatc atagctcttc
     8581 ccattggagt tgaagtatca aattgttctt tgatagatat aaatgatatg tttagttcat
     8641 ttaatttttc tattaaagta gagaagtcag atacatttct cgatatccta tctaatctat
     8701 aacaaactag gtaactaaat ttcttatctt tggcatcctg catcattttc ttaaattgtg
     8761 gtctatctat attgctacca ctaaatccct catcttcata tatcaaaaaa tcttttacac
     8821 caatagactt tgcataatca atacataatt gtatttgatt ttctatagaa tcaccttttc
     8881 cagtaaatct tgattttctt gaataaattg cagctttcaa aattaaaacc tcctataagt
     8941 taggatatat atttgaaact atttatctac aaccttttaa gtaaacttat tagaatgaat
     9001 ttattaatta ggtaaattta tataattcta ctttttataa tatatgacta tttattttat
     9061 ttctttacta ttcaagttct aaatcaataa taaattttga tatttaattg tatcaggaca
     9121 aatctctaat ttcatagatt attaatataa aatcataggt tagtgtgaaa aagttgaaat
     9181 ttaaatattt taaaagataa tttttttgaa ctaataggta taacaaaaat ttataggggg
     9241 attgcatatg gaaatcaatg ttatagaaat tttccctaaa gataaagcta aacttaataa
     9301 aatagaaatg gataaagcta gttggtttgt aaatataata agtaaaaaat atcctaaaga
     9361 agctttaaat gaagcattta gtactttaga aaaagaatta aatataagta aagctaatac
     9421 ataagctttg attattgatt ttatatacta ttggttttat acgctatgac ttgacattat
     9481 attaatcaaa tagtatattt ttaaatatag cacaatgaag tgttaaaaga gcaatggagc
     9541 tccatagata aagtctatgg agcttttttg cgtatttaac ttaaggagga taggactttg
     9601 aataactttg agattaaaac tagaataaaa tttggagaag gctcactaaa agctttgcaa
     9661 gaattaaaaa acaaaaatgt actaataata acagaccctt ttatggtgaa atcaaaaaca
     9721 atagataaaa taacatctaa tttaataaac tcaacatatc aagtttttga agaaatagta
     9781 ccagacccac caatagaagt agtagtagca ggaatagaag catttaaatc tataaatcca
     9841 gacgtaataa tagcattagg tggtggttct gcaatagatg cagcaaaatc tataatggac
     9901 ttttctaaaa aaatattaaa aattaacgaa gtagagttta tagcaatacc aacaacaagt
     9961 ggaacaggtt cagaagtaac atcatttgct gtaataacag atagtcaaaa aaaatgtaag
    10021 tatccattag tgagtgatga tttacttcca gatatggcaa tactagaccc agaacttgta
    10081 aaaactgtac caaattttat aacagcagat acagggatgg atgtattgac acatgctata
    10141 gaagcttacg tatctacaaa ttctaatgac ttttcagatg cactagctga aaaagctata
    10201 aagttagtat ttaaatactt aataaaagca tataaagatg gaaatgacat agaagctaga
    10261 gaaaaaatgc acaatgcatc ttgtttagca ggtatggcat ttaaccaagc atcacttggc
    10321 ataaatcatt ctattgcaca tgtattaggt ggaaaattcc atataccaca tggaagaaca
    10381 aactctatat tacttcctca tgtaatagaa tataattcat caatagtagg atatactaac
    10441 acaacttact ctgctacagc taaaaaatat gcacaaatag cagaattagt aggacttggg
    10501 agtgctaata taagaatatc tgttagaaat ttagtaaatg aaataaagaa actacaaaaa
    10561 gaaatgaata tgccaactaa attgacacaa tgcaaattaa gtttagaaga tataactaat
    10621 gaagaaagag aaatagcaaa acttgctata aaagatactt gtacattaac taatcctaag
    10681 gtaccaactg aagatgatat aataaacata ttaaagaaca ttaaataact acattttatt
    10741 acatgtaaat ataatattat acaaataggg aaaatgtttt taaaaatata aattatatat
    10801 tgacaaatat aaaacataaa actataatga aagtatcaca aaggcgtgat actttagtag
    10861 aaagcaatgg agcttcttag gaatattaat attattctta tggagctcct tttattttaa
    10921 tcaaatagct ttttaataaa ctatattcaa agaaagcagg gaataaattt gactgaagaa
    10981 tctaagcaaa gagttattca agaatatgtt cctggaaaac aggttacatt agcacatatc
    11041 atagctaacc ctaatgaaga tatatataag aagttaggat tagtacttga taaaaaagat
    11101 gcaataggaa tacttacaat aacaccaagt gaagcgtcaa taatagcagc agatgttgct
    11161 acaaaggctt caaatgtatc tttaggtttt atagatagat ttagtggttc agtagtaata
    11221 tcaggtgatg taagttctgt agaatcagcg ttaaatgatg ttttagaagt cttaggaaat
    11281 atgttaaact tctcatctac aaaaatcaca aggacataat aatacaatga agaatataat
    11341 atttatggga aagacaggta gtggtaaaac taccttatgt caaaaactag accagttaga
    11401 attaaagtat aaaaaaactc aatcagtgga actttataat aatgcaatag acactcctgg
    11461 tgagtatatg gaaaatagaa acctatataa tgccttaata acaacatcag cagatgctaa
    11521 aattatagca atagtgtatg atgccacaca agaagaaaat tatatagcac caggttttgc
    11581 cagtatgttt tgcaaagacg taataggaat tataactaaa ataaataaag ctactgaaaa
    11641 cgaagtcaat atagcttatg aaagactatc actagcagga gcaagtcaaa tctttaaaat
    11701 agacacagtt gataatattg gacttgaaaa attatttaaa tatctaggaa aatataaaaa
    11761 tatagatgaa gtttaagggg aaatattttt ttattcaaaa atattattaa agtatgataa
    11821 aataaaaaaa tgtataaact attttaagaa gatttaatct ttaagcgagg taggaacatg
    11881 gggaaaaaaa tactattggt tgatgatgaa ccactgttaa ggatggatac aaaagatata
    11941 ttagaaagtc atggctatga aataataggc gaagcaagtg atggatttga agctgttgaa
    12001 atgtgtaaaa aacacaaacc tgatttagtt ataatggata tagagatgcc aatacttgat
    12061 ggtataaagg caggcaaaat aatatgtaaa gaaaatctag ctggtggagt acttttatta
    12121 acttcatttg aagataaaga atacgtagaa aaggctaaaa gtataggtgc ttatggatat
    12181 ttagtaaaaa cagcaagtga aaaatcactt atcccaacca tagaaatgtg tttaaataag
    12241 gtaaatgaat ttgaaaaaat gaaaaaagat ttagaaaaag taaattctaa attgaatgaa
    12301 agaaaattag tagaaagagc aaaaggtata cttataagag agtttaagat ttctgaggat
    12361 gaagcataca ctagaataag aaaattaagt atggataaaa gaactacaat gatggaaatt
    12421 gccaaaatga ttataatagg atacgatgac taatacgata aaaaaaatat caactgcaca
    12481 aacatactta aataataacg aaattgaaaa aattatagaa gtatcaaaat ccttagattt
    12541 aatggcttct ttttatgaag ctgatgtttt tatagatgta ctaagtaaat ttgatgatga
    12601 agcaattgtt gtggcacatg gtagacctaa agaaaagtca atgtactgtg aaaatgttat
    12661 aggtaaaaag gctttaattg aaaatgaacc aggagttata aagtgcttaa aaacaggaga
    12721 aagagtaaga gatattaaag ctttaacaca ggaatataaa ctggtcaaac aaaatattca
    12781 gccaataaca ctagatgaca aagttttagc agtactaata gttgaaaaag atataagtag
    12841 tgaagttaag aatgagttta atgctagtga agacgaagaa aataaaaatt tacatcagtt
    12901 tataaaactt ataggaaata atgacttttt agttgataat ttaaattcag ccatattaat
    12961 atttgataaa aatggaaaat taaaaattaa aaatcgtatt gcaactgaga tatacaaaaa
    13021 tcttgggttt ggatatgata tacaagatat gcattacaat gatttagata tagaaaccaa
    13081 cacctttgaa aatatattaa tggatgaaaa ttatgatgag acaaatgaag tttcaatagg
    13141 taatatgttt tttaaaataa agaccatata catcaaagat gatgaattta aggtttgcaa
    13201 aatagtacaa gatataagtg atttaaagag aaaagaagaa gaattagttt tgaaaacagt
    13261 ggctataaga gaagctcatc atagagtaaa aaataatctt catacagtaa tatctataat
    13321 aaaaaaacaa agtagattat ctcaaaatga tgaagtaaag cagtgtttag ataacataat
    13381 aaatagggta tttgcaatac tttcgactca ttatttacta tctaaagaag ttgataataa
    13441 tatatctata cgagaaggta tcaatttatt agtgtcaaat attcaaggtg gctatttatt
    13501 tagtaaggat atagatatac gtataactgg tgaagatttt aaaattagtg gagaaaaagc
    13561 aacagcaata cttttggtta taaatgaaat actacaaaat tgttatgacc atgcattttc
    13621 ggatagagaa catggtacta tacaaatatt aataaataaa gataacgact atagaaatat
    13681 tgctattata gatgatggaa ttggatttga tagtaataat ataaataaaa atagcttagg
    13741 gacatatata atagatagtt atataacaca gatgttaaaa ggaaatatag agagaaaaag
    13801 tagtgagaat ggtacagaag tattaattac tatacctaca caaattaata tttaaataat
    13861 aactcatcta caaagtagta gttttaattg agcaaagagg cttaaggtta ttaatagatt
    13921 aagttaattg aatgtattta taaaaattat aagtatatat tcaatttaac aggtatttat
    13981 tataacttta agcctctttg cttgtttaag acatacttaa attttaggag gtgagaaaat
    14041 gagagaagag ttattaagtg ttggtattga cattggaaca agtactactc agttaatttt
    14101 ttctaaatta atagtagaaa atactgaatc aaatttttcg gtacctagaa taagtatagt
    14161 agacaaagaa attatttata aaagcaaagt ttatttcacc cctcttattt caaataatga
    14221 aataaatggt caacaaataa aagatatagt tgaaaatgaa tataaaaaag caaatatatc
    14281 taaagaagat atacatacag gagcagtaat aataactggt gaaacagcta gaaaagaaaa
    14341 tgcaaatgat gtacttcata ctttgagtgg atttgctggg gacttcgttg ttgcaacagc
    14401 aggacctgat ttagaaagta taatatcagg aaaaggagct ggagctcata tttattcaaa
    14461 agaacattca actacaattg taaatataga cataggtggg ggaactagta acatagcctc
    14521 atttaaaagg ggagaagtaa ccgatactgg gtgtttggat ataggtggaa ggcttgtaaa
    14581 gatagataaa ataagtaaaa aaataactta tatatcacct aaaatagata aaatcataaa
    14641 agataataat ttaaatcttc aagtaggcac aatggctact gtagaaaata caaagccaat
    14701 agtggatata atggttgact tattaatgga aagcatagga ttaaagaaac agacaccttt
    14761 gtttgatttt ataataacca ataaatcaat aagtatagat gaaaatatta aaaatgtttc
    14821 attctctggt ggagtagctg attatattta ctatgatgga gaaataaaag attattttga
    14881 atatggtgac ttgggaattt tacttgggca agcaataaaa aattgtgaat accttaaaaa
    14941 agtaaatgta gttaaatcta tggaaacaat aagagccaca gtggttggag caggttctca
    15001 tactactgaa gtaagtggaa gtacaataac ttacactagc gaaaagtttc cacttaagaa
    15061 cttgccagtt ttaaaattat caattgatga agaaacaggc acttcaaaac aaatcagtga
    15121 agctataaaa aataaactta attggtttaa actagaaaat gatttacaga aagttgctat
    15181 agccatgata ggaaagaaaa atccaacctt tttagatata caagagtatg ctaaagggtt
    15241 tgtagatgga atgcaacaaa tcatagaaaa tgatttacct tttatagtaa ttgttgaaaa
    15301 tgatatggca aaagtgttag gtcaagcaat atatgcatta ttaaattatg aaaaagaaat
    15361 tgtttgtata gacagtgtca aggttgaaaa tggagactat atcgacattg gaaaacctat
    15421 agttgaaggt aaagttttac ctgtggtaat aaaaacatta gtttttaatt aatagaagga
    15481 ggtaagtaaa tgattttaaa tacaaaatta tttggacgta cttatcagtt taaaggctta
    15541 tatgatgtaa tggctaaagc taatgaagaa aaatcaggag ataaattagc aggtcttgca
    15601 gcagaatcag ctgaagaaag aatagcagca aaagttgttt tatcacacat aaaattggag
    15661 gatataagaa ataatcctgc agtggcatat gaagaagatg aagtaacaag aataatacaa
    15721 gatgctgtaa atgaaaaagt ttatgaagaa ataaaaaatt ggacagtctc tgaacttaga
    15781 gaatggctat tggattcaaa tactacaagt cttgatataa gaagaatatc aagaggatta
    15841 acttctgaaa tgatagcagc agttgcaaaa ttaatgtcaa atatggactt agtttatgca
    15901 gctaaaaaga taaaggttac tgctcactgt aatacaacta taggagaaca aggaacatta
    15961 tcagcaagac ttcaacctaa tcatccaaca gacgacccag atggaatact tgcatcactt
    16021 cttgaaggtt taacttttgg tataggagat gcagtacttg gattaaatcc agttgatgac
    16081 tctgttgaga gtgttactaa agtattaaaa agatttgaag aagtaaaaca aaaatatcaa
    16141 ataccaactc aaacatgtgt attggcacac gttactacac aaatggaagc aataagaaat
    16201 ggtgctcctg cagatttaat attccaatct atagcaggtt ctgaaaaagg aaatgaagca
    16261 tttggattta atggcgacac tatagaagaa gctagacagt tagccttaaa acacggtaca
    16321 gctacaggac ctaacgttat gtattttgaa actggacaag gttcagaatt atcttcagaa
    16381 gcacatcatg gaatagacca agttactatg gaagctagat gctatggatt tgctaaaaag
    16441 tatgaaccat tcttagtaaa tacagttgtt gggtttatag gacctgagta cttatatgat
    16501 gctagagaag ttgtaagagc aggacttgaa gaccacttta tgggtaaact acatggctta
    16561 ccaatgggtg ttgatgtttg ttacactaac catatgaagg ctgaccaaaa tgatatggaa
    16621 aacttagcca tactattaac aacagcagga tgtacgtatt ttatgggaat acctcatgga
    16681 gatgatgtta tgcttaacta tcaaacaaca ggataccatg aaacagcatc acttagagaa
    16741 atgtttggac taacagcaat aaaagaattt gatgcttgga tggaaaagat gggattctct
    16801 aaagatggta agttaacaga gttggcggga gacgcatctg tattattagg ataggaggta
    16861 tttaatatga atgagaagga tttaaaagca ttggtagaac aattagttgg acaaatggtt
    16921 ggagaattag atactaatgt tgtgtctgag actgttaaaa aggcaactga agttgtagta
    16981 gacaacaatg cttgtataga tgatataaca gaagttgata taagaaagca attactagta
    17041 aaaaatccta aggatgcaga agcttattta gatatgaaag caaaaacacc tgcaagatta
    17101 ggtataggaa gagctggtac tagatataaa acagaaacag ttttaagatt tagagcagac
    17161 catgctgctg cacaagatgc tgtattctct tatgtagatg aagaatttat aaaagaaaat
    17221 aatatgtttg cagtggaaac tttatgtaaa gataaagatg aatacttaac aagaccagat
    17281 ttgggaagaa aattttctcc agaaactata aataatataa aatctaaatt tggtacaaat
    17341 caaaaggttt taatattagt tggagatggg cttagctcag ctgcaataga ggcaaattta
    17401 aaagactgtg tgccagctat aaaacagggg ctaaaaatgt atggtataga ttcaagtgaa
    17461 attttatttg ttaaacattg tagagttggt gctatggacc acttaggtga agaattaggt
    17521 tgtgaagtta tatgtatgtt ggttggagaa agaccaggat tagttactgc tgaatcaatg
    17581 tcagcatata tagcttataa gccatatata ggaatggcag aagcaaaaag aacagttata
    17641 tcaaatattc acaaaggtgg aacaactgca gttgaagcag gtgctcatat agctgaactt
    17701 ataaaaacta tgttagataa aaaagcttca ggaatagacc ttaaataaag tcgagggagt
    17761 gtagaatatg aaaaatgatg taattcgtcc taatatacta ggaattaaaa taatttcaaa
    17821 tataagtcca gaaatggcac aaaaactaga attaaaatca catcacaaaa gcttaggttt
    17881 aataactgca gactgtgatg atgttacgta tacagctctt gacgaagcaa ctaaagcttc
    17941 agaagttgat gttgtatatg caaaatcaat gtatgcaggt gctgcaaatg cttcaacaaa
    18001 acttgctggt gaagtattag gaataatagc aggtccaagc ccagcagaag taagaagtgg
    18061 tctaaatgca gtagttgatt ttctagagta tggagcaact tttataagtg caaatgatga
    18121 tgattcaata gcatactatg ctcactgcgt atcaagaaca ggtacatacc tttcagaggt
    18181 agcaggaata agagaaggtg aagcattagc ttatttagta gcaccaccac ttgaagcaat
    18241 gtatgcacta gatgcagcaa tgaaagctgc agatgttaag atgtgtgaat tatttgcacc
    18301 tccaactgaa acaaactttg gtggagcatt acttacaggt tctcaatcgg cttgtaaagc
    18361 agcatgtgat gcatttgcag aagcagtaaa atcagttgca gacaatccaa caggatttta
    18421 aggatagtta gatggatgct ataggcttaa tagaagtaat aggatatgtt gctgcaatag
    18481 aagcttctga tgcttgttta aaatctgcaa atgttaatat tgtaagagtt gataaggttg
    18541 gagcaggtat tgttacttta acaatatgtg gagatgtcgg tgctgtaaaa gctgctttag
    18601 aagcaggtga aatagcagct tccagagttg gtacattaag aacatcacat attataccga
    18661 gaatccataa tgaagtaaca aatgctttat tcaaaactaa agaacctaaa gtctgtgaag
    18721 tttcagaaga taaagaaaaa aactttgaga ttacattgga aatagctgat aatgtatcga
    18781 aaaatttatc agaaaaagaa aatgtaattt tagatgtcaa tgaaaacagt ggagatactg
    18841 aaaatttata tagtgatata gataaaacaa acaaaaaaat tgaaacagtt gataatagtt
    18901 taacagaagc taatgaggaa aaaatagaaa acactaatga taaagaagta ttggaacaag
    18961 ttaaaataga aaatttcgat tttgatagag atgacctatc aaagaacagt gtaaaaaaac
    19021 ttaaagctat ggctaagaaa ttagattctt caataactta taaagattta aatgttctta
    19081 aaaaagaaga attaataaac ttagttaaaa agcttagtag aagggataga tagttatgac
    19141 acttttagat aaagatttag tatctataca agaagtaaga actcttgtaa gaagatctaa
    19201 agtggctcaa gagaaacttt ctaaaatgag tcaagagcaa atagataaaa tagtaaaagc
    19261 tgttgtagat gcagcattta ataatgctac taaattggct aaaatggcaa atgaagaaac
    19321 tggatttgga aaatgggaag ataaagtaat taaaaatact tttgcatcta tgggagttta
    19381 tgaaacttta aagaacacaa aaactattgg aataattggt gaagataaag aagccaatac
    19441 gatagatata gctacaccag ttggagttgt tgcaggtctt ataccttcaa caaacccaac
    19501 atcaacagta atatacaaaa ctataatatc tctaaaagca ggaaatacta tagttttctc
    19561 tccacatcca aatgcaaaaa actgcatact tgaaacagtt aatataataa gtgaggctgc
    19621 tataaaggct ggagctccag aggattcaat attatgtata actaatccaa gtatagttgg
    19681 aaccaatgaa ttgatgaaac ataaagatac aaacttaata ctagcaactg gaggagaagc
    19741 aatggttaga gctgcttact cttcaggaac accagctatt ggagttggac caggaaatgg
    19801 accagcattt atagataaat cagcaaatgt taaattagca atcaaaagaa taatagattc
    19861 taaaactttt gataatggtg ttatatgtgc atcagaacaa tctatagtaa tagaaaaatc
    19921 tatggaagaa actgttttaa aagagcttaa aaatcaaggt gcatatgttt taaatgaaga
    19981 ggaaagtgaa agattagcaa aattcatatt aagagctaat ggtactatga atccacaaat
    20041 agttggtaaa agtgttgagg taatagcaaa tttagcagac ttaacaaatg tacctaaaaa
    20101 tacaaaagtt ctagttgcaa gagaaaataa agttggtcac aatgtagcct attcaagaga
    20161 aaaacttaca ccaatactag cgttctatgt tgaagaaaat gtagaagcta ttatgaacag
    20221 atgtagagaa atattgttaa atgaaggtgc aggtcataca ttctcaatgc atgtaaatga
    20281 tgaagaattg gtaaaaagat ttgcccttaa tatgccagta tcaagaatac ttgtgaatac
    20341 tccttcagca cttggaggaa taggtgcatc aacaaacctt gtaccagcac taacacttgg
    20401 ttgtggtgca ataggtggaa gttcaacttc aaacaatata ggaccacttg atttaataaa
    20461 tgttaaaaga gtagcttatg gaatcaaaga aatagaagaa cttggaagag ataaatctca
    20521 agttgaaaaa tcaatgtttg actcaatgga taaagaagaa ttaataaatc ttcttgttca
    20581 aaaactagtc aaagaactag cataactaaa ataaacaatg aaacttatag ctatcgctat
    20641 aaatttctaa aaatataaac tataaaaaac tataaaatta aatttttgga ggataagatt
    20701 atggcaagtg caaacgcatt aggaatgata gaaactaaag gattagtagg agcaatagaa
    20761 gcagcagatg caatggttaa agctgcaaat gtacaattag taggaaaaga gcaagtaggt
    20821 ggaggattag ttactgtaat ggtaagagga gatgttggag ctgttaaagc tgctacagat
    20881 gcaggagctg ccgctgccga gagagttgga gaactaatat cagttcatgt tataccaaga
    20941 ccacactttg aagtagatgc tatattacca aaggtatcag ctgagtaata taagaataat
    21001 tataaaattt aaattttgat tgaaaaagag gctatctcaa aaatgagtct tactaataaa
    21061 ctcaatgtat tttgaggtag tcttttttat acatctaata ggagatgtga taaaatgggt
    21121 gttttaacag aaaacgaagt aaaaagaaaa attggaaaaa acaaaaataa tataactgaa
    21181 ttttatatag aaaaaggtca aataataact ccttctgcaa aatcttattt agctgagaga
    21241 agtattgagc ttaaatatgt tgataaactt tcagatgtaa acaatgaacc taaagaagtt
    21301 gtaaaagaag tatttaaaga gaaaaaatat aaatatacta ctgtatttgg cgctaaattg
    21361 gatgaaaaac cagaacatat gactcaatta aatggaaatc ttttagtttt taaagaccat
    21421 aaaagaataa tattgagagg aaaaatagat tctcttgaat cagaaatact aaaggtacag
    21481 atactttgtc aaaaactaga tatgccaaag cttgttaagg aattgcaaga agtattagac
    21541 tttgtaagaa atataatgag atgtgaagtt ttagatgaaa agctagggga ctttaaactt
    21601 ttaggattaa ctcctcaaga acttagagaa caatctcact atcctaaaaa atactttggt
    21661 ataggacatg agttcccaag ttatgaaatg ggagaagtag tagtagctat aaatagtata
    21721 agaagtaata cacgagaggt tgaacttgca gcctatgaag catttaaggg tgagtatgga
    21781 aatgttcaca gagaagattt aataaaggca cttaatagat tatcgtcagt attttggata
    21841 atgatatata aggttagaac taataagtat aagtagttgg aggacataat ggagaatcta
    21901 ttaaatgaaa tagtggaaga agtaataact agagttaaaa aagaagcatt tatagaagtt
    21961 gaagcatcag gaagacacgt tcacttaagt agagaagatg tcgataaatt atttggagaa
    22021 ggatatactc ttacaaaact aaaagaccta tctcaaccag gtcaatatgc atgtaaggaa
    22081 agagttacaa taactggtcc taaaggaagt ataaaaaatg tagttgtact tggaccatgt
    22141 agaaatgaaa ctcaggtaga aatatcttta acagatggtt caactcttgg actaaaagct
    22201 cctataaaac aaagtggaga cttagaaggt actttaagta ttaaaatatc aacacaatat
    22261 ggtgaagttg aacttgataa ggggctaatg gttgctaaaa gacatataca catgactcct
    22321 aaagatgctg aaaaattcaa tgtatgtgat aaagagatag ttgaagctaa ggtgatgggt
    22381 caaagacctt taacatttga tgatgtagta ataagagtga gtgacagttt taaaacttat
    22441 atgcatatag actatgatga agccaatgca tgtggttatt caaaaggaac tgttgctaaa
    22501 ataataaaga aagcataaat ttaacctact atataaatta cctctaggga ggatttaata
    22561 tgaattatga taaccttgta gatttaataa cggaagaaat ctataaaaaa ataaatagta
    22621 atgaaataaa aatatctaat aaacctaaag ctgtgattgt atttgaacaa gataacaata
    22681 aatttaactt attaaaagat gaatttgaaa tagtagaatt tgataaaagt ataagggaat
    22741 gtgaaatagt gatagtttca agactttgta tgagggggct atcgaatata gcacttggaa
    22801 attcaacaag tgatgaagaa agatttatac taaaaatgat tatgaagggc aaaaaagtat
    22861 atgtcctaga tgaaggaatt gaatacaaaa aatataagga tactgcacca aaagcattat
    22921 ataagaaatt tatgtcattt gaagatgaaa tatgtaaatt tggtgtagaa attataaaag
    22981 acttaaatgt tataactaaa aataagttaa atataaagaa agaactagaa agtactagag
    23041 gttctaaaaa agaagataca aaagttttag ataaagatgt tttaaattta accagtgtcg
    23101 aaagtgtaaa aatagataat gaatttagtt tagatttaag gaataaaaaa cttatatcgg
    23161 aagctgactt aagaaaacca actataaatg gagttaaaaa catattagtt aataaaaaaa
    23221 gtataataac accattagct gtagatttta tgagaataca ccatctcaaa ctaaagaaac
    23281 tgtaaggagg taattttatg gatataggaa aagttgtagg taatgtttgg gctacaagaa
    23341 aagatgaaaa attatgtggc caaaaacttt tagttgtaaa aattttaaaa actaaagaca
    23401 catacaagga aggcttcatg gttgcagccg ataatgcagg agcaggaaat ggagacttag
    23461 ttcttatatc caaaggttcc tcagctagag agtcgattga aaaatctcat gttccagtag
    23521 atgcaactat agttggagta gtcgattcgt ttgaggtgtt tgatgaataa aagtatagga
    23581 gccatagagt ttaaaagcat tgctaaaggt atagaagtat ccaatgaaat gataaagaaa
    23641 tcttcagttg atgtattgta cttaaaaagt atttgcccag gtaaatttct aataatagta
    23701 ggtggagaaa cttcttatat aaatgaatgt gtagattatg gaataaaact tggagaagga
    23761 tatattgtag ataactttgt aataaatgca atttcacaag aaatattaga tggatttaaa
    23821 aataagtatc aaaagctaga tagtatagtc tctataggcg ttgttgaaag tagtaaagta
    23881 tgcgctggaa taaaaatgct tgataagact ttaaaatctg gcgacttagt attagtaaaa
    23941 cttcaattat cttttgctat aggtggcaaa ttagtatata tagtagcagg agatttaagt
    24001 agtttagaat atgcattaaa agaaagtgaa aatgtagtaa gagaaaaaga agtaatatat
    24061 aagactgtaa taccatcagt agacagtcaa ataataaaaa gtctaataaa ataatggggg
    24121 gaattatgag tataaacgaa attataatct atgtaatggt agtcttcatg gtacttggag
    24181 ctatagataa atgtataggt aacaaatttg gtcttggaga acaatttgaa gaaggtataa
    24241 tggcaatggg gtcacttgca gttgcaatgg ttggtgttat atgtttagca ccagttcttg
    24301 ctgatgtatt aagaccaatt gtagtaccag tatttaatat acttggagct gacccagcta
    24361 tgtttgctgg aagtttatta gctaatgata tgggtggtgc gccacttgca cttgaacttg
    24421 cgaaagaccc taatgctggg ttatttggtg gattaatagt aggggctatg atgggaccta
    24481 caatagtatt tataatacca gttgcgcttg gaataattga aaaagaagac caaaaattct
    24541 tagcaacagg aatacttgca ggtataataa caatacctat tggagcattc gttggtggat
    24601 tagttgcagg attcgaggta atgatggttc ttagaaactt agtgccaata ataatatttg
    24661 cagtagttat agcacttgga ttattaaaat tcgaaaatgc tatgataaaa ggattcacat
    24721 actttggaaa aggtgtagta atagttataa ctttaggact tgctgctgcc atagttgaag
    24781 ctttaacagg aatagttgta atacctggaa tgaaaccaat cagtgaaggt atagaaatag
    24841 ttggagatat agcaatagtt ttagcaggag cattcccatt agtgtttgtt ataacaaagg
    24901 tatttaataa accattaatg gctttaggaa aagttcttgg aatgaatgat gtatcagcag
    24961 caggccttgt tgcaagttta gctaactgta taccaatgtt tggtatgatg aaagatatgg
    25021 acaatagagg aaaaataata aatgtagcat tctctgtatc agcagcattc gtatttggag
    25081 accacttagg atttacggca ggatttaatt ctaatatgat aacaccaatg atagttgcta
    25141 aattagttgg tggtataaca gcagtattgt tagctatggt tatcgcaaat aagacactaa
    25201 agaaggagaa tgtataagat ggatatatca aatatagata aaaatttaat tgaaacatta
    25261 gtaagacaaa taatagaaga aaaaataagt ggaactaaag acacagtaga ttttgttaga
    25321 aataaagaca ttagtggaat aacttctata aagttaccaa ctgtaaaagt tagtgaatct
    25381 gatagattag atacagggaa tccaagtgat gtagtttaca caaaagattt atttacatta
    25441 gaggaaagcc caagattagg ttgtggtatg atggaaatga aagaaacaac ttttgattgg
    25501 actctaaact atgatgaaat agattatgta atagatggaa ctttagatat aataatagat
    25561 ggaagaaagg tttctgcttc ttcaggtgaa ttaatattca taccaaaagg aagtaagata
    25621 caattttctg tacctgatta tgctagattt atatatgtaa catatccggc agattgggca
    25681 tctcaaaatt aataaaaatc aagttaagtt aataataatc aaataaataa tttaaaatac
    25741 aaactcttaa ataagcacac atatttaaaa aagctatgaa ttaaaattca tagctttttt
    25801 tataaagaat gttatatttt agacgtattt tttctatatt tactgggaga catattatat
    25861 tttttattaa ataatctaat aaaatgctct acatttggat aaccaatact attttactga
    25921 taatcttttc cttatcacta atcttacatt ttaaaatatt atttttactc gtaatattat
    25981 cataagaatt tgtttcttat ttaaaactaa ttagaattat aaagtttatt gccatgttat
    26041 taataaaata aatccagtta aatcgagtgc tagttaaagt aataagaaac ttttacaatg
    26101 gtttccttta tcgattgaaa taaaagttaa tatggtataa tatctaaaga gagaatctta
    26161 tcaattagaa tatgcataga aacaagtggc ttaaaaggag acgttatatg gaagagatag
    26221 taaagaagga acaagcaagt atgaatgata tttttttgta tcttaaagct aaatcaaact
    26281 cattatataa atttgtaata ttatataatg agtttatcaa taaacctaaa gattatggaa
    26341 ctggggaact tataaacatg gttgaagtac atatgctaac agcgattgaa gaaaatccag
    26401 gaataagtcc aactcagtta gctaaaatat ggaacagaac taaaggtgca atatctcaaa
    26461 ctatatctaa attggagaaa aagggttata taactaaaga aaagaaagaa ggaaatgcaa
    26521 aaactatatt actatatcca accacatcag gagtagagtt aagtaaggca cataaactat
    26581 atgacaccat agatgttaca agaacatttg aatacttaat caaggagtgt acattagagg
    26641 agatagatag tttttataaa gtaattgatt tgtttattaa tttattagaa gaatctccgc
    26701 aggaaaataa tgattctgaa aaagtgtagc taagattgaa gttgaataaa gagaaataga
    26761 tattatagaa gtagtactta agtacacatt atataaaaat ataataggta taggattaaa
    26821 aagtttagtg gtttaaagtt taaccactaa acttttttaa tgtctataat ctactattat
    26881 ttaatttact aaaaataaaa aaactcatta tattaagata aaaatagaaa aataactaga
    26941 aaaatactat aatatatcag cttaatacag aaaaaagtta aaaaatttga gaaaaataaa
    27001 aatgaaaacg ttttatattg acatagagaa aaagtagtga taccatttaa atatagttta
    27061 gtagctaaac tatatttaaa ttataataac tattttaggg ggatgttatg aatttaaaac
    27121 aattaagtga aaaatacgaa gaatatgtaa ttcaaatgag aagagaattt cataagtatc
    27181 cagaattatc ttttaaagaa ataagaacaa cccaaagaat aagggaagaa ttacaaaaaa
    27241 taggggtccc ttttgtatct attgaaccaa atatcgtaat agctactata caaggcaaaa
    27301 atgaaggtaa gacaattgca attagaggag atatagatgc gcttccaatg caagaagatt
    27361 cagatgttga atacaaatca gaatatgatg gaataatgca ttcttgtgga catgatgctc
    27421 atggagctat gttactagga cttgcacata tgctaaatga tataagaaaa gatttaaaag
    27481 gtagagtatt attagttttt caagcagctg aagaagttgg tggtggacac aaggagataa
    27541 tacagtactt taaggaaaat ggaggaccag atagattaat agctactcat gtttggtccg
    27601 atattgaagc tggtaaaatt tctgttgaac caggacctcg tatggctggt gggtctggtt
    27661 ggagaataga cataacaggt agaggaggtc atggttctag accagatcaa agcatagatc
    27721 ctataaagcc agcttgtgat atagttttaa aagtatcttc tataccagtt aatcatataa
    27781 gtgtactaga acaatgtgtt gtacatgcat gtgcaataca tggaggaact acaataggaa
    27841 atgttattcc aaacaatgca gaggtaatag gtggatatag atattttact gaagaatcag
    27901 gcaaaaaagt gtttgacatt ataaagcaaa tgagtaatgg tgttggacaa gtttatggag
    27961 tggatgtgaa ggttactcat actggaggca taggacctgt tatcaatgat gaagaagcag
    28021 ttaagatggc taaagaaata gtttctaata tagatggatt ggagttagat tcttatgagc
    28081 caatatgtgc atcagattgt tatggtgaaa tattaaaaga gtattctggc ttttattgtt
    28141 atctaggggt aggtaacaaa gaaaaaggaa taatatatgc acaacaccat cctaagtaca
    28201 atatagatga agatacatta aagttaggtt gcgaatttat ggctaaatat gcagttgaat
    28261 ttttaaataa aaataataac taaaataaat cgaattttat aaatgggggg atgaaaatgc
    28321 aaggtgcatt aaaggaaaat aagaaaaaaa gtggtggagg atttttagga tggattgaaa
    28381 aagttgggaa taaaatgcca catcctctag cattatttac atatattaca ttgatagtag
    28441 tagcattatc tgcaatagca agctttttag gtttttcagc aacaagtcct gctacaggaa
    28501 agttaataaa agttatgaac ttaataagtg caaaaggttt agtactattt atgcaagagt
    28561 ttgttaagaa cttccaaaac ttccctgtgc ttggagtagt tttagttatg gcagttgcca
    28621 caggagtttg tgaaaagaca ggattttttt caactgccat aaaaatgagt ttatcaaaag
    28681 ttaaggggaa tgcggttgta tttataatag cttttatagg agtatttgct aatcaagctg
    28741 gtgatgctgc ttttgtatta gtaccaactc ttgcaggagc aatattttat ggattaaata
    28801 gaaatccatt agctggtata ttctgtggat ttgcatcagt tggtggtgga tttgcaacag
    28861 ctgtaattcc tgggggatgg gacgttacgc taacgccaat aactgtatca gctgctcaaa
    28921 ctattcaacc tgcatttgat atgacattat tagctagtta ttatgcacta tttgtatctg
    28981 cgtttatagt agctacagta tcaacaatag taacggttaa atttatagaa cctaaattag
    29041 gtaagtatac tggtaaacca gaaggtatag atgataatca agattttgag gtcacaaaag
    29101 aacaagcaaa agcagcaaag ttagcaggtt ttacagtttt agcttatgta gcgttattaa
    29161 ttgctttgtg tataccagct aatagttttt taagaagtcc agaaggttct ttaatatttg
    29221 gagcaccact tatgtcttgc ttacagtttt ttatagtaat actattcttc ttgccaggga
    29281 ttgtgtatgg aatgagggtt ggtaaaatca agactgtaaa agacttaaat gatatattat
    29341 gtcaatcaat ggcagcaatg gcaccgttta tcgtacttgc aatagttata ggtcaattct
    29401 taacgctatt ctcagtgtct aatttggcac aggtactagc tataaaaggt ggagcattac
    29461 tcaactcatt gccactacca ccacaagtta taatactgct attcttagta ctagtagcgt
    29521 ttataaatat atttgttata agcggaagta caaaatggat gatatttgga ccagtatttg
    29581 ttccaatgtt aatgcaatta aacatacatc cagcatttac tcagtttgta tatagattag
    29641 gagattctgt aaccaatcat ttatcaccat taaatgcatt ctttataata cttttagcaa
    29701 cagtccaaaa atacgataaa aatgcaggta tgggaactat attctcagct atgatacctt
    29761 acactatagg ttactttgta gtacttgcag ttttagtagt agtttggatg acaataggta
    29821 taccagtagg aataggtgga caagtttggt tataaaacat atttaataat tttgggagga
    29881 aagaaaatgg aaacaactga aataagatac aattttgatg aagtaataga tagaagtgga
    29941 acaaactgtc ttaaatatga tcttaagagt caatttatgc cagaatctcc agaagatgca
    30001 ctaccactat gggtagcaga tatggatttt gcatgtgccc ctgagataat taatgcaatg
    30061 catgaaagaa tagacagaaa aatatttgga tatagctctc aacaaactga tgattattat
    30121 gaagctgtat gtggatggtt taagagaaga tttgattgga aaatagaaaa agagaatata
    30181 ttctttagcc caggggttgt gcctgcgtta ggatttttca cacaaatatt aacacaaaaa
    30241 ggtgatggta tcataataga aaagcctgta tactatcctt ttgaagataa aataactaac
    30301 aatgaaagaa aagtagttaa tagtccttta aagtttgaag atggtcatta ttctatggat
    30361 tatgatggat ttgaagaatt agctaaagat gaaaataata aggtgtttat attatgtagt
    30421 cctcataatc cagttggtag agtatggaaa aaagaagagc ttagaaaaat agtagacata
    30481 tgtaagaaat atgatttgtg gataatatct gatgaaatac attgtgatat tattcgtaaa
    30541 ggtgaaaagc atataccatt agaagtagca tgtcctgatt ataaagatag aataataact
    30601 tgtacagctc caagtaagag ttttaactta gctggtatgc aattatcaaa tatagtaatc
    30661 aataataagg aattacaaga aaaatggatg cttgaaacag attctaaatt agctatattc
    30721 ctacctaatc cattcgcaat agttgctact aaagttgctt ataatgattg tgaagattgg
    30781 attaatcaag taaatgagta tatagatggt aatattaaat atgtagaaga ttttgttaat
    30841 gagtatatgc ctaaagtaaa gataataaaa tcacaaggaa cttacttagt ttggttagac
    30901 tttagagggt atggattaga tgcaaaacag cttgaatatg taatgcttaa caaggcgaag
    30961 gtattgctag atgaaggata catattcgga gaagaaggag caggatttga aagaataaat
    31021 gttgcttcac ctagaacaat tatagaagag tgtatgaata gaataaaatg tgcatttgaa
    31081 ggattataat agtaatatct aaataatata tttgtgtatt ttaaaaaaag actatgctaa
    31141 aaaatatttc aaagcatagt cttttaaagt tttatgatga gtttaaaaaa tttcaaaacg
    31201 ttactattca cttatatgtt tatattagaa ataattccac aatatactca ttttctaaag
    31261 ttgcactttt atacaccttg cttcaccaat atcatgtgta accaaaatag tagacttatt
    31321 ctcattctta ataatactat aaacatcatc acaaactaat aatctagtct gataatcaag
    31381 agctgaaaaa ggttcatcta aaagtagaat atctggattt acagaaagtg ttctaataag
    31441 cgcaactctt tgtctcatac ctccagataa ttcttttgga tacatacttc taaaatccca
    31501 taatccataa gtctttaaaa ggctttcaac tctatctaaa gattttttat cttttttgcc
    31561 ttgaatttcc aatccaatag ttatattatc cattatattt ctccattcaa gcaaattatc
    31621 tttttgaaac atatatccaa tatttccagt aatctttata tcaccactag tcggttttaa
    31681 aagattagta agaatattta atattgtaga tttaccactt ccagaaggac caagcaaagt
    31741 taatatttct ccttctttca agttaaaatt gacatccttt aatacttcaa gctcgccttc
    31801 cttagtgtag aagttcatat ttatattttt aacttctact atgttgtcat tcattatgcc
    31861 accccctata acttttagct cgtatatatt atgttattaa caatatgacc tatttgtacc
    31921 atttttcata aatataatat aaatattttg tttatttacg tattttctta gtaacttgta
    31981 cgtataaatt atagataaat aaattataag gtaggggata aatttgagta acataataac
    32041 gaatttaata gagtcaatat ttactaatcc aataactata ttgtttttac ttgcaataac
    32101 tgtgtattct gtttttaaaa taatagaaaa taacagagta tattcatttg taagttcaaa
    32161 attagacgaa atcaatagag actataagac aagtgagttt tataaaaagg taagggatga
    32221 ctactataca tatagtaaag aaaatcctta tgcagacgta aatataactt catttataga
    32281 ggaagttgta tctgatttaa agcataataa tttgccattg ttagaaaaaa ttagaagtat
    32341 aaaaaattca tcttcaataa gtatattact tggggtttta ggtacgtttg ttggtctttc
    32401 tacaatgctt ttatgtgttg atactaaaga cattataaat tcacttcctt caactattag
    32461 tagtatgcaa actgcattta caactagtat atttggagtt gtattttctc taattatagg
    32521 ttactttact aagataaaag attgtgaaca tgttttgata caaataatgt taaaatctga
    32581 aaatttacta acatctgaaa taactcattt taagtcagaa agaatggatt taaaagtaga
    32641 agaggtaaaa aatacaataa aacaaataag taagtctata gaagctattg aaaaatttga
    32701 taaaatatct aaagatttaa atgactttaa tgatgaattt atcagtggta tagaagcttt
    32761 aaaaagcctt ttagaaggtt ctcaaagttc tattaagaca tttgaccaga gcgtaagaaa
    32821 attagataaa cagtttaata ttttaaatat aaaatttgta aagctttttg ataaatatga
    32881 taatcaagat aatataaata aagagatttt atttgatata aaagaatctt caaaaaatat
    32941 atacaatgcc actgaaagcc aattcaaaat tagagattat ataaaaaata taaatgcagg
    33001 atttgctcta tatgaaagaa gtgctcaaga tttattaact aaattaatga cccatgaaaa
    33061 taaaatctct caaaatcaaa aaatcctttt agatgaaaag tttaccttag atgactcaat
    33121 aaaaaatctc tcaagtatta ttgaaaactt ttctaatgac ctacaagtta aactggatat
    33181 gatgtttgaa aattctttag atattcaaga taagttagat gttatgttta ataactcttt
    33241 tatgaatgat gaagttcctc ttgatagtga agaattattt aaggatgatg ttaataatgt
    33301 atttaatcct tttagtgaag aaatttatga gatagaggat aaagaaataa aggtcatagg
    33361 tgaggatgag ttaaatgaat aataaatata gaagaactgt taacagggaa tttgaaaaga
    33421 gtagcttttg gccaacattt acagatttat tatctactgt attgatggtt gtaattctta
    33481 tcttatttag ctcagaaagt atttcaggtt ctgttgaaca agatttagct aagaatgtca
    33541 atgcttctgt tgaagaaact tttaaaaaaa gtggaatacc tgtgaaggta gataaatcta
    33601 atgggcaagt aacttttggt gaaaaaacca tgtttgatgt agatagtgat gttttaaaac
    33661 cagaggctaa agaaatgcta aaaatgtttg ttccaaagta catagagact atttataaag
    33721 attatggtga ctatatatcc aaaatagtta tagaaggtca tacagatgat gtgggaagtt
    33781 atatatacaa cttagattta tcacaaagaa gagcatatag cgttgctaaa tttatagttg
    33841 gagatgaaat aggtgactat aaatacaaag ataaagtgac taagcatatt attgcaatag
    33901 gaaggtcaaa agctgaactc atcaaaaatg gtgacaatag cgtgaataga gatgcatcta
    33961 gaagagtaga actaaaatac gaaataaata ttaatcaaaa taaataatta aatttttata
    34021 aaaaaaaaga aggcagttgg tgtgagcttt aagccttctt taaggaaaaa gtttatttat
    34081 ttttgttgat acttaacata ttatagtttt tagaagcagt ttgcaatata ttaaacgtaa
    34141 atggtcgttt aaaatgcata actggatact actgatgtaa aatatttcat tttatataat
    34201 ataaaaatta tacagtgtca attttctata ttattgtact ataatctatt atttaaaata
    34261 ttatgtaaaa aaatatcata aaaacgcata tcatgttata attactagag tattatgaat
    34321 atggaggcgt agtttgtgat agaaataagt ataaaaaata aaaaaaattc taaaattaaa
    34381 actttgatac ttttattgat agtatctata tcgatttatt taactggttg tactacatca
    34441 gataatggaa ataatcaatc aaataataat gattctttgt ctagtagtat atcaagtgat
    34501 aagaatgtaa aaattcattt tattgacact ggaaatagtg atgcaatatt gattcaagat
    34561 ggtaaaactt ttacattgat agatggggga gataatgatg atgagggatt aatggtagat
    34621 tacctaaaca atcaaggtgt aaaagatatt aaatatctta tagctaccca ttctcatgca
    34681 gaccatttag gtggacttga ttctgttgtc aaaaacttta atatagaaaa tgtttttgta
    34741 tcgaatggtt cagcagaaac aaagagttat agggacttta taaatgcttt agcaaataag
    34801 ggtttatccc caagtgtacc tcttgaaaat aataagttct atttagaaga ttcttatttt
    34861 gaagttctaa atacaaatgg gggagatact actaatgaac aatctctagt ccttgtatat
    34921 actaatggga atgataaagt tttatttaca ggtgatgctg aagaaggtac cgaaaaagaa
    34981 atactaccta agcttgagaa agtagacctt ttaaaagtag ctcatcatgg ttctcgtagt
    35041 agttcatctc aagagttttt agataaagta aatcctgaat atgcggttct tttagtaggc
    35101 aagggtaatt catatggtca tccacatcag gagacaatga ataaattaaa aaaaatggga
    35161 gtaaaagtac atagaagtga tgagtgttca gatataatat ttgaatcaac aggtgatgga
    35221 gtatttacaa gttgtaaaga tggaagttat aataaaggcg ttagagaaga tggaaactct
    35281 ggaaaatcaa acagtaatac aagtaaaaat gattctttta aaaataaaca aaatacatcc
    35341 aattcagaag aaatagtgta ttttactcca aaaggtaaga gttatcactc tacaaaaaat
    35401 tgtagtgggc tttcaagaag taaaaaaata ttatcaggca caattgcaga aagtaagaaa
    35461 aatgacccat gtgatatatg ttatggaaaa taacaaaaaa acaaccaatt tatctataaa
    35521 gcttctgaac tttaaatcat ttaaaaaata aaataaatgc ataaaaaaat aagctataat
    35581 caatagataa cacattttat ctatacgaat agcttatttt tttaagtatt ttttaatagc
    35641 tatttaataa ctctaaatac accagttaca atacctacaa tttcaacttc agagtcattg
    35701 agcataattg gttccataaa atcattttct ggctgaagtc ttattaaatt tccttcttta
    35761 aaaaacctct taactgtagc agattcacca tttataagtg caactactat ctgagaattt
    35821 aaggctgtat tttttttgtc tactacaacg taatcttcat ctaaaattcc tgcattaatc
    35881 atactttcgc cttttactct taatacaaaa ttgttactgc cctttactaa actggcaggg
    35941 aatggaatgt attcctctat gttttgttga gctaaaatgg gttctccagc tgttatttga
    36001 cctactaaag gaagctctat tatttcttga ttagctccag aaacatcatt tactttacta
    36061 cgttctaaaa cttcaatagc tcttggttta gtagggtcct ttcttatgta tcccagtttt
    36121 tcaagtttat ttagatgaga gtgcacagtt gaagtagatc ttaaccctac agcagtacat
    36181 atttctctta cagcaggtgg ataacctttt aatatgattt gagactttat aaattccaat
    36241 atcaagactt gcttttcagt tagatctaaa tacataacat cactcatttc caaacatatt
    36301 ttgtttttat ttccatacac tttatatttt taattataac ataatccatt tatatctgca
    36361 aacatttgtt cctgattttt aatcgtcctc aatccattca aaattcttga ctatatcacg
    36421 ttttacattt ttcttatgag ctgcataaag ctgagtagtt gtgacattat catggtcaag
    36481 taagttttga acatcatata tagaaaatcc tgtttggatt agagaagttg cagccgttgc
    36541 tcttaattta tggggactat atccattgtc tctagtagta tcaagtggaa tagatgtata
    36601 tttttttacc agtgttctta tagcctttgc tgtaattctc ttattttgaa gagacaaaaa
    36661 taaagcatct ttttcttcat catttaatag ttcatctctt gttctttcgt tttgcaaata
    36721 atcttttatt acatgttcac aagtatgatt tataggcatt aaaacttctt tcccacgttt
    36781 tctatatatt ttaaattcac ctcttgaaaa attaaaagag gagatattga gttctctaag
    36841 ctcatttaat ctaagcccgt atgtaacaaa taatgctagt atagctttgt cacgtaattt
    36901 agtttttctc caatatacct tttctttctc tgtaagccct tcacctgttt ctactgattc
    36961 aagcatctta gcaacttcat ctatctcaag gcgcttaata gcatctggct gaggtttagg
    37021 aagttttatt ggattaaatc catcagttat attattatct atctgagagt ttctgtataa
    37081 gaatttaaat agagtagaga tggatgattt ttttcttgct aaagctctat tgttattttc
    37141 aaaaatcaat gtgttttttt ctgtattttt gtaatatcta ctgcaataat cacctaagaa
    37201 taaatttata tctcttgatt ttattgtatt aaaatcatct tctgtaatat cttttacaca
    37261 atctgcattt gttaattctt tggtttcaat caaatatgaa caaaaaaaat taatatcttc
    37321 taaataagca agtcgtgtag aaactgcaac agaacctttt aaatatataa aataatcctt
    37381 cataaataca ggaagtttat tttccaaaag tagacatttt tctatgagtt cattttcttt
    37441 gataacaata ttatcaggtt tatctgattt attatgtact tttataattt tcttatcatt
    37501 attcaaaatt aaacctccta aaactaaaat ataaatcttt tatattattt tttgatattt
    37561 ataccaagtg agtataaata tttaatttaa tcatttttta catttttaag agattagcag
    37621 tgctttagat gaaattatca ctaactattc cctaaatcca catttaaaga ctagttgaat
    37681 ttaattactc tttttttatt tctcaatata tttatagaaa tattttaaaa tatattgaga
    37741 aattttttat gctctactaa aatctttttt atataatatt tttatatgtt tctaacgaaa
    37801 ccaaatatta gtaaaatatg tatttattta actaaagttt ttaaatgggc tgactaagct
    37861 taaaatatag gatattatga gagttactat tgaaaaaata aaccctattg ccataaagaa
    37921 acttataaat atgttatact taactattaa actggatata ttcaagttat caaatccaaa
    37981 taagtatgta attgaactta ttacaaaaat aactataact ataaagctca gaccatttaa
    38041 gctatttttt aaatcagcac tactaagtga catatgtgta gatatagaat acattaaaaa
    38101 cataaatata aaatacttca atgaatatac actaggtgtt aacaacatta ttcttataaa
    38161 attggaaata tcacctaaaa taatgtgtat aaaaccattt atatttaaat tattaatcat
    38221 acttacatat aactttaaat ctatattttg agtcactttc atataactat ctggcagtaa
    38281 tatcttaaaa attaaaataa tcattattgt tccacctata ataggtgcaa ttcctataaa
    38341 gaaatttcct atactttgat aaagattatc ttttttatag ctatgactta catatcctag
    38401 tataccatca tttttacttt ctattggtct gaaaaattta actgaattta ttttatgcat
    38461 gaaaatcaaa cacattatca aatgactcaa ttcatgaaaa aacgttccta tagctccagt
    38521 tacaataatt ccagtttttc caaaagatga aaatataaat ttattattta gattttctgt
    38581 aatgctaaaa atcaatccaa atacaataaa tattcctatg aaacaaaaaa tatttattac
    38641 acttattttt aaaatttcga ttatataaat cataagttaa gtcctcatgt aaaagtattt
    38701 aactactcta cttcatatcc attacagctt aaaattttac aagcattttc tatatctttt
    38761 tcttttacta agatatagtc tgtatcataa gtagaaattg caaatatgct tattttgttg
    38821 tctgctaaca aactacttaa cttagataaa attcctacaa gtgaaaagtc taaaggacct
    38881 agtatcttaa gtattctcca ctccttttct gacttgacat cagaaggaat attattattt
    38941 aaacatacaa cacttaattc atcatcagtt ctagttatag aataaaactt ctctgtatct
    39001 atccatgttg gtattttact gtcattattt aatctacata ctgcatactc ttctaccaat
    39061 aattttaatt tcataatgta tatttcctcc aatcttattt gtttacttaa gattatacat
    39121 taaaagttac ataaaataaa acatataaag taaaaaaggt tcactatagt gtcctatttc
    39181 tatagccaac ctttaaaact taattaaatt ctaataaaga gatatattat ctaggttcaa
    39241 ttataagttt aatggctgtt ttcttatcac cttcgatttc tatatcagta aatgcgggaa
    39301 tgcaaactaa atccattcca ctaggtgcaa caaaacctct tgctattgca attgatttta
    39361 tcgcttgatt tagagctcca gctcctatag cttgtatttc tgcaacgcct cgttctctta
    39421 gtactccagc caaggctcca gctacagaat taggattaga ttttgatgaa acttttagta
    39481 cctccatttc aacatctcct tgttaatttg ttaaagtatc cattacctaa agtactaaat
    39541 cataattgcc atttactaat tacaatcatc atttaaagta tacttttata aaaatatact
    39601 tctataatcg ttttaagaaa acctttattt tttttaacca ttttattatg aaaaaactac
    39661 aaatttcttt atattctata agcattttcc aatatttcta aattttttat atctttgagc
    39721 tataatttcc tctttatcca tatctttgta atgatttaat ctttctaaaa tataagcttt
    39781 tatttctttt gaaacagctt ctacatcttt ttgtgctcct ccaagaggtt cttttataat
    39841 cttatctatt atttttaaat catataaatc attacttgta agcttcataa catcacaagc
    39901 ttctttagct ttagatgaat ctttaaatag aatactagaa agcccttctg gagaaattac
    39961 agaataaact gaatgttcta acatacaaac atcatttcct actccgatac ctaaagctcc
    40021 tccactacca ccttcaccaa ttacaaaagt gattactgga acagaaagtt tactcatttc
    40081 aagtaagttt cttgcaatag cttctccttg tcctctttct tctgcttcta gaccacaaaa
    40141 agctcctgat gtatcaataa acgttattat aggtctatta aatttttcag cttgtttcat
    40201 aagtcttaat gcttttctgt atccttctgg atgaggcatt ccaaaatttc tttttatatt
    40261 ttcttttgta tctcttcctt tttggtgtcc aactatagta acattaaact ttcctatctg
    40321 accaattcct ccaaccatag aagggtcatc tttaaaaagc ctatctccat gaagttctaa
    40381 aaaattagaa caaatatgtt ctatgtattc caatgtcgta ggtctcttta tatctctact
    40441 tagtgttacc ttttcatatg ctgatagatg tgaaaaagca tcttccttaa gcttttccaa
    40501 tttctcatta agtgaattta ttttatcact taaatctata ttatttgcct tagaaatagt
    40561 tattaattgt ttaatatcat tttctaagac ttttattttt tcactattat tttcaatcaa
    40621 aacagttcct cctttatgcc ctatttcttg tgcatagcaa gaatttgata taatacttcc
    40681 ttcatttttc ttctatctac tatcatgtca ataaaacctt tttcaagtaa aaactcagaa
    40741 gtttgaaatc cttcaggaag tttttgattt attgtttgct ctattactct tggacctgca
    40801 aaacctatca acgtatttgg ctcagaaatt ataatatcac caagcatagc aaaactagca
    40861 gttactcctc cagtagtagg gtcagttaga actgatatat atggcaatga tttttcttca
    40921 agcttagaaa gtgcttgaga agtctttgcc atctgcataa gagataccat accttcttgc
    40981 attctagctc ctcctgaagc agaacaaata attataggta aattattttc agcagcatac
    41041 tctattgaat aagttatttt ttccccaaca atagaaccca tacttcccat cataaaatca
    41101 ggattcatta cacaaataac tgttttaatt ccatttattc ttccataacc tgtgacaaca
    41161 gcttctgact cttttgtttt ttccttataa gagtctactt tttctttgta tttaggaaaa
    41221 tttagtggat tttgaaattc tacatcagaa ttaaactcca taaaagttcc tttatcaatc
    41281 aataaattta ttctttttct tgctcttaag ccataatgtc ttgaacattt tggacataca
    41341 aatgaatttt cttctatgtc ctttctaaat acatgactat cacaaccttt gcaataggtc
    41401 caaaatttat catctacact attcttttta aagttgtcat ctaaagaaat cgtaacatac
    41461 ttagattctt ttgatgataa aaattttttt atcataatct atttactcct tataatgtag
    41521 caaattcttt cttcataaag acatcttcta taaatttggt atgatgagta tcttctctaa
    41581 actcctcact tgttacaagt gccttttgaa attctacatt tgtattaata ccttctacaa
    41641 taatttcgtc tagagctcta tatattctac ttatacattc ttctctagtt tcagcccaac
    41701 atattaactt acctatcata gaatcatata aaggtggtat agtatatcct gcatatacaa
    41761 aagtatcaaa tctaacacca aaacctccag gtaaatttaa tgattctatc ttacctggtg
    41821 atggagcaaa attctttgat gaatcttctg catttattct acattcaata gcatgacctc
    41881 taaaagtaat atcttcttgt ttaaaaggaa ttttatcccc attagctata gatatttgaa
    41941 gttttataag gtcaagattt gttaccatct ctgtaactgg atgttcaact tgtattcttg
    42001 tattcatctc tataaaataa aagtttttat ctttgtcaac tataaactca atagtacctg
    42061 caccgatata acctactcct tttactatat ctactgcaat tttatgaagt ttttgtcttt
    42121 cttcatctga aaggtatgga cttaaagatt cttctattac tttttgattt cgcctttgca
    42181 tagaacaatc tctatcacct aaatgtattg catttgaatg tttatctcca aatacttgta
    42241 cttctatatg tctaggattt tctataaact tttccatata taaatcacta ttagaaaatg
    42301 ctgctagagc ttctgaactt gccatatcaa aatttgaaaa aagttcttct tcttttctaa
    42361 cgattctcat accttttcca ccgcctccac ttgaggcttt tatcataaca ggatatccaa
    42421 tttctcttgc aacttctaaa gcttcttcct tagttttcaa aacagattct gaaccaggaa
    42481 caacagggat attcaattcc atcatagttt ctcttgctct agatttatct cccatcaaaa
    42541 tcatttgttc tcttgttgga cctataaaaa taatattatt atcttcacat tgctttgcaa
    42601 attcaggatt ctctgataaa aatccaaagc ctggatgaat agcatcacac tttaatttaa
    42661 gagcaagata gattatattt tctatattat tataactctt acttatatta tttggtccta
    42721 tacaaataga ttcatcagct atatatctat gaaaacaatc tttatctatt tcagaataga
    42781 tagcaacagt ttttatacct agttctttac atgttctgat gattctaact gctatatcgc
    42841 ctctatttgc aactagtatt ttttttatca acttaaatac ctcctactac aatggtttta
    42901 tcttaaataa aggttgatta tattctacta gttcttcatt actaactaat acttcaatta
    42961 tttcaccttt aatttcactt gttatctcat tcataagctt cattgcttct aatatacata
    43021 aagtgtcgcc ttcttcaact acatcgccaa ctttaacaaa gctatctgca tctggacttg
    43081 gagaatcata gaatgttccc atcaaaggag ctactactac tgatagattc tcattagatg
    43141 tgacaggtgt atcgtttaca actggctttt ctaaagaaag atccactact gattcttgtt
    43201 gtacacttaa aacaggtgaa cttgtagatt gagctttttt agatacttct aatcttaaat
    43261 cgctactttc aagttttaca tattctaagt tagttgagtc tatggcctct aataattcct
    43321 taatttcatt gatgttcatt ttgttacccc cttgtattat tacctggtgc taatattata
    43381 tcacaaaaaa caaatttata aaagaaaaag tgctgactag agaatcaaca catcaatata
    43441 tcttttaatt ttaaattaac aaccagtaac ttatatttgt tttaattttc cattattaat
    43501 ataaattata agtataaaat gaataaaatt caatattttt tgcaaaatac aagagaatac
    43561 aaattaatac ctcgggaatt tttaagacaa ataccaatat tatgcaattt agacttcgct
    43621 ttctttcaaa ttagtatcat tttctttatt tttacatagg atgtacttta atttagctat
    43681 caaaacattg ctatataggt taaaagttat tagaattgca ggaattataa agtaaactct
    43741 agcacctata aaaccaaaaa ctactgtaat aagtattaat cttttattta aagtaaaaaa
    43801 aggtatatta aaaatacttt tgtcggatgt ttctggagta taagaatata taactccaaa
    43861 aatcaaagta agcatacaaa gtggaagtag tgtataactt gaaattattc ccaaaaatcc
    43921 tatactttca aaatatttgc tagcactatt tgtataaaca aacatgtatc catttaaata
    43981 tgcgcatata catgatataa tgccaaaagt tccccctaag gattgagtgt accaattaaa
    44041 aaatttagat tccatatacc tcacctccta aaactgtata tataatgata tgcatttaaa
    44101 tagtaaaata tatctttata tgtttctgaa taaaattttg ttaatttcat taatttatgt
    44161 ttaagaaatt tgaagtatag tgtagtatat attaatgtag atgaagtttt atagtactta
    44221 tttcatagtg cttaatcaag ttatcttatt atggattcaa aagttgtttg tagggtttta
    44281 tattttgttg agctgaaaaa tttattataa atgaagggat gttttcgctt tggtagatac
    44341 attagaattt ggtcttaaaa ttttattttt tatattatca ataatttgga tgggtaaaat
    44401 aatgatttta agaactgata agcaaatagt aatcaatcct ttgcttattg gtatatctgc
    44461 aatccttgtg atgttgcata cctcacagag taacattgaa ttttttggat tagatgtcca
    44521 atatataaga atagttttgt atataatata ttcactgata attttaatag gaatatgggc
    44581 tactaacaga agaaatggaa ttttttagat aatctatttc tataaaattt aaaggttgct
    44641 agtaacaaat cactaatatt agcgttctgt tactaacaac ctttattttg attatacact
    44701 taaattgaaa atagaatgat tgaataagtt gacagattat tttacattga cagtaattag
    44761 aacttcttga gatgtattta aatcattttt gtcgcttagt ataactttta ccactgcttg
    44821 acctgtttta ttacctttaa ttatcatatc ttcacatgaa agtacactct tatcacttac
    44881 agatacaata aaatttaaat cttttggaag gttatcagta acttcccagt atttataata
    44941 actatcaatt ttcttcgtaa ttatttttct caaatcaata ctttcacctt ttgctatatc
    45001 aacattatga tatttagagt ccagtttata ctgattatct tttgtatcaa taaaatttaa
    45061 atcgcaattt acatccacac cattatgaga aagagaattt actacatcgt catcaatcaa
    45121 ataattattg gcaagattta ttgaatccat atcttttaga cttaaagctt ccttaggaac
    45181 ctcttttata ttattattcc aaaaaataaa attgtctaca ttttcaagat atgatatacc
    45241 ttttaaattt gaaatactct caccagttgc ataaaattct ccatctaaag cctttatatt
    45301 gcttatagtc atctcatctg gatttatata tctttttaca actgctctta aatttgcatc
    45361 aggaaaaata tctttaagtt gattttcgct caaaacctta tcatttgaat ttattggact
    45421 taaagctgct gcagaaataa taaatggtat taaattagct aaattcatag taccctccca
    45481 cataaatttt ttattataat aatttaattt ctatgagagg gttctgtttc cttgttatat
    45541 atacctactt tcgtacactt tattaatata aattaaaata aatttctact attaaactta
    45601 taaacatatt actagttacg ttttttagct tcacatctaa atattcgcat accttgtgac
    45661 ataaatttgt cttcatactc tgttgtaaca ttattttcat actcactatt tcctaaatca
    45721 agagaaatat tctttaatag ccaattattt gcagcaattt catttaaact aaactcgaat
    45781 aatttttcat tatctgtttt aaagtgaatt tcgccatcat cttccaaaac cctattgtac
    45841 atttctaaaa atccagaatg agtgagtctt cttttactcc atctattttt aggccatggg
    45901 tcacagaaat ttatataaat tctcgataat tctttagctt caaagtaatc caaaatattg
    45961 cttacatctc cccataaaaa tagtatatta ttcaaattag aagcatctgc tttttcaaca
    46021 gcttttaaaa gaacttcttc cttaagttcc atggcaatat aatttatgtc agggttctgc
    46081 ttagctaaag ttgttataaa cttacctttt ccagtcccaa attcaacatg tattggatta
    46141 tcatttctaa actttaaatt ccacttgcct tttaatttgt ctatatcgtc tcttaaaaca
    46201 tattttgtat aacttaaaag cttttcatct gcaccttttt ttcgtcttct tctcacaata
    46261 attctcctta catataaaaa attagtaaaa tacattttta ttatacatta tctcaccaaa
    46321 aaataaaaag aactctctta aaatagaaat ttatttctat aaagagagtt ctaaacttac
    46381 taaaaactta atcttagtgg caccctgaac aaccagagca tcctcctcca ccttgatctt
    46441 tcatattttc aggaataact ctaaatccaa atcctgtatc ttctattatt atatctccat
    46501 actgactata ttcatcagag ctcattacaa attgtaactc tccaacttca taagttaagt
    46561 catcttcttt tttctcatct aaagctaatc caaaagaagg acctccacaa ccaacacctg
    46621 caaagtatac tcttatatta ttaggtttat cttgattgtc ttttaagata ctttttaaag
    46681 tatcaatagc tgtttctggt aaagtaattt tcatcaaatc attccctttc aaatatttta
    46741 ttaaaacaat atctattata tacccataca aggtacataa tcaattagtt tttgcatatt
    46801 ttactaaaac ttctacctaa tattacctaa ggctttaaaa tattttatat aatattttat
    46861 taccttaaat aaatacccta tcataaactt agtaaacaaa taaaattatt attctaaaaa
    46921 atataataat tttatttgtt gttttaatat tataacacat ttgataatgt ccaattcata
    46981 tatgcaaaat ttatatactt taaaatatct aagaaattat tcaataaaaa aatactattt
    47041 tttaaaaatt atcattattg ataaagctct actatttata ttttttagtg tattcatgta
    47101 taataagtaa aagcacaacg gtatatactg ttgtgctttt ttgtaattaa taaacaatat
    47161 tttggtctat aacaatgaaa aatggctact ttccataatt gatttcatct gacataagca
    47221 aaaagggtgt ccagctgggt caatcataac tctccagtca tcagtaaatt gctcctctgc
    47281 gattgtagct ccacaatgaa ttgcatattg aactgcttct tctaaatcct taacagcgaa
    47341 atccatatga gccatttgct gttgagattc aggtttttct ggttctatta tgccccaagc
    47401 ctttgttttt tgcaatataa agaaaaaatt atatatttta atattttata cttgttgaaa
    47461 ttgtgtaata aattcaactg gatacatagt gcgttttgaa atttcttcta aagctaaacc
    47521 ttgttttaaa agcctcttta tgacgctttc catactttct gaaatttcta taatattttt
    47581 atcaaaatca taaaacctaa aagttctttg accccatggg tattctttta tataatgtaa
    47641 aaattcaata tttcctattc tatttatctt actttcccat tgtttgatgt cattaacctc
    47701 aaaatacaac tgaaagttat ttgattgttg atatattggt aaatcatatc caattatagc
    47761 tttataatta ctttgtaatc caaatccatt ttcaaatgat acatgttctc ctaaatctaa
    47821 tgtgattttt tgctccataa catcttcata aaactttttt gatttattta tgtctttgac
    47881 aattagcaat actcctccaa atttcatctt atcactatcc tttctttgtt ataagtatta
    47941 taacttaaaa ttttgcaatt tcactgtaaa aatcagacat attagctcgg tatttttgag
    48001 gagttattcc acagacaatt ttaaaatctt taataaaatg tggtatatca tagaatccta
    48061 attcattaca tatagacatc aatgaagttt tattattgtt tagaagtttt atagatttat
    48121 taatacgtac caaacgagaa aatgacttca tactcaaccc tagatactga ttaaagagtc
    48181 tgtttaaatg cctagaacta taaaatactt ttttagaaat ttcttgtgaa gatatatttc
    48241 cagagttttg aataatcaac tgaattgcca aaataaactc atatgagtat tcaattttaa
    48301 tattagaaat caataattct tccaacttta aaatcaattt atctatagat aaagattcat
    48361 taaatatttt tttaatttct aaatctaatg aagtattaat tatagaaaat ggaacaactt
    48421 tatcaataag ttcactttgc tgtataccta taagcgggaa aaaaccagca ggttgaaatt
    48481 ctataattag tataacatca catctattag caatatttcc tactgttttt ggtttagtag
    48541 ttggaccaaa taatagacta tgtaaccctg tggcatcata aaaaaacacc aaagttacac
    48601 ttccatgagg aataatcgtg taattatcag aaattattgt ttgatttgga aacgatatag
    48661 taaaattcga tatccaattt cttaattgta tacaaggcaa gagataaaca aaattgtctt
    48721 cacaaactat aagtgaccta tttttattta taaaatgaat actttctttt tttaacatat
    48781 attatatcct gtcctatcgt gaatatttat taaagtaaga agaatccata ttatctctat
    48841 atatcattaa ctgcttttaa taatagagat agtatgaata ctcattagat atttaataaa
    48901 caaataaaat taaaataatc aataaaaaat atagtacttt tatctgttat tttaatatta
    48961 tagcacactt atagtattta acttatatcc actttacata tgtctaattt atataattaa
    49021 aaaatgctta tctcaaatac aataattagt ccttatacaa ttaaaccatc tgaaactgta
    49081 atagtacgac tactactttt ggctgcttct ggtgagtgag ttaccataat tatagtttgt
    49141 ccattgtctc tgtttatttt attcagtaaa tctattattt ctatccctgt tttactatct
    49201 aaatttccag taggctcatc agcaaataaa atctctggtt ttccaattaa agctcgagct
    49261 atagcaacac gttgttgctg accaccagat aactctcgtg gtgtatgttt acgtctatca
    49321 gttaaaccaa ctatatctaa gatttcatct aattgatttt tataatcttt taaattttta
    49381 ccatctaata acaaaggaag cattatattt tcctccacat ttaaatttgg tattaagtta
    49441 taaaattgaa atacgaatcc tatatttcta cgacgtatta tgctcatttt ctcatcatta
    49501 aaatgtgata tatcagctcc attcatatac acttttccgc tcgttggagt atctaaacca
    49561 cctaaaatat ataaaagagt acttttacca gaaccagatt gacccatgat agaaacaaat
    49621 tcacctttca ttacttgtaa agatacctct tttaacactc gagttgttgt atttccaatt
    49681 ttatattctt tgataatatt ttttgcttct acagctaaac tattatgtgt aattttcata
    49741 ttaacctcca taattattca aacttaattt cttctatcag tttcattttc ttccctttta
    49801 taataggcac tatcgaacct attaaagtta ctataattcc caataaccca acaataataa
    49861 atgttttaaa atctaaatct ggtttcattg aaatttttgg tcctgcaact ataaagatag
    49921 tttgaatctc aagtatagat atcacaatac caataacagc tccaagtaaa cctgaagtaa
    49981 acccttcaat caatgttact tttatatttt gtttattact tagtcctata gatttataca
    50041 tagctataga acgtcttttt tgaatataat taatcagtag attattaata atacctactg
    50101 tagcaagaag aaaaatgaaa taggtcatct tattcatagg agacaaaaaa ctacttatag
    50161 tatttaaaga atcattatta aattcttcaa ctgtacgact ccaattatat gtatctccaa
    50221 ataaatatct tatctgaatc ataacagcat ctggattgac tgctgtatat actaaaaaac
    50281 cataattagt tttatcaaaa tcattaactg cataatgtga tggtataaca gcttctacat
    50341 catttgcacg ggatttaaaa ctacctacta ttttataaga aaaatcatac ttatcattag
    50401 atagagttat tgtatctcct atagataagc ctactttttt tagagtatct tcattcaaaa
    50461 taacagaacg tttatcatta aaagcttcta ttacttgttt ttttatctca aaatttgtat
    50521 aattgattcc aaacatagag ttatatagtt ttatattatc tgtaccctct agtcttgata
    50581 atgttacacc attaccagaa atctcattat tcataacata aagaggtaat atttttttaa
    50641 ttccatccat atgtctaaca tcttcaataa actcttcatt catctttcca tctgcaaaac
    50701 cttgtaattc tgcgtcacga aacacatctg ttatataagc tttaacaaag ttaccaacaa
    50761 cacttattgc aataactgca gaaatactta taaatagtaa agtgatattc tgtattatat
    50821 ttttgttatt tttcatattt ctagcagcta atttaccctc attccctaaa atatttttat
    50881 aaacaaactc aaaaactata gacatgatat cagtaataag aggaatcaac acaatagtag
    50941 ctacaattaa tcccagtaat gaaaatccac cagctagata caatgtattt tcaggggata
    51001 ttcttggaag taaaatagat aaaataaaca ttatacttcc tataaaaagt atagaacgat
    51061 ttgaaacatt cttttcttct actgttccta gtacaatatt ttttattggc aaatggctag
    51121 cttttttaac aggtatatat gcactaaatg aagaaacgat tattgctact ataacagata
    51181 taatcactcc aatgggtgat attactactg gaattgatat tccttgttcg agagaatttc
    51241 ctaacccatg aagcattaaa tttaaaacaa ctacaccaat aggaatagca attaatcctc
    51301 ctatacttcc gtataatata ctttcaagca tcaatatacg agttacggtt ttttcattgg
    51361 caccaatact tctaaatgtt ccaataaaag gaagacgttc taatgtaata accttataac
    51421 tgctgtatat tataaatata ctaagggtta atgcaaaaaa acttattaaa aagaaaggca
    51481 ttgtcttttg tctagcatct gaaattatct tagtttcatt tatagtattt gataccatat
    51541 atttttcagt agaaagttct tcggataatt tatttactag attttctgta atttcttctt
    51601 ctgactctat aagaactctt gtatatccac tgcctttatt tataattttt gatagagtct
    51661 ctttgggtag cagtgcattt acacctcttg tgttcctcaa aaatactgta tcataagatg
    51721 caatatcact aacttgaaaa gtataggact ttccataaat ctgtaaagta atagaatcac
    51781 ctttttttat tttatatttt gatgtaaagc gatttggaag aataatttta tcaccagaaa
    51841 aatcagtaat actatcgcca ttttctaatc gtggcttgtt gattttattt agttgactta
    51901 agtctgctga tataagacta aattcttcat agtatacccc tttattataa atagcagagc
    51961 tttccaatac accaaccttt gattttatag catttaaatc aggtatgtct tctaaattgg
    52021 ttaatatatc tggattttta ctttggacag atatagtcgc tgtaccatac ataccttttg
    52081 ccatttttct ttgtgcactt tcataagata atccaattga gaatgaaaca aaaagtaaaa
    52141 ctgttgataa aactatggac aataacataa ctgctgttct aatttttcgt tctttaatat
    52201 ttgtgaaaat atactttaat ataattttca aatttacacc ttctttcctt atctaagata
    52261 tttcaatcta atatttttat actttaatct aaattaaatc tctaatagac tcctccatac
    52321 ttttatcatt ctatttataa tatttttaat caaatcaccc cttaaataaa aaagattgat
    52381 aaactactat ataaatataa taatctatca accttaatat attttttatt taaccttaat
    52441 taaccttaat taaataggaa aggtgatata aaatgagcta cctaatcctg gtatactttc
    52501 aacagatata ttccctccat gaacttcaat aatttgcttc gttattgcta gtcctaaacc
    52561 agttccttct attttttgtt ttgtattgct tcctctataa taacgattaa acaaatttga
    52621 tgcttcttct cttgacatcc cttttccatt atcagatata atgatttcaa ttctttcatt
    52681 taatgttata tgtacacaaa ctttagtatt tttatctcca tatgtaaaag cattgacaat
    52741 aagattacta aaagctcgtt ttaatagtgt acaatcaaaa tcaaagttaa tattatctat
    52801 attactctta aattcaacta tatttgattc atattctgga taatttaaaa tatcaatgga
    52861 taattctttc aagaatctta ctaaatcata attattttta tttaaaggga ttattccatt
    52921 ttttaattga taggttaatt ttaaatcgtt tataagtgta tttgtatatt ctatattctt
    52981 taacatgatt gaagcatatt tatatacttt ttcaggtgaa taattagtac tactatctgt
    53041 aagaagctct gcataccctt ttattggtga aagtggagtt tttaaatcat gagttatatt
    53101 tgaaatccac tcttctctca taatatcagt tttattttgt atctcatcac ttttatgaat
    53161 ttcttcattt aaaatattta aactattata tatatcagca aaaacacctt taatattaac
    53221 tggaagatag cttcgttttg aaatatcgct aacagcagat gtaatatttg atatgcactt
    53281 tgttacccag taaccataag caattccaga aaccaaaatt attaaaaata taatccctat
    53341 gattgaaaat acaattgact taccacctat aaatttacct ccatcaaaaa acatattcac
    53401 tttagatata tttaatggaa aatatataat ataaatatag tcatttttat tatttttaat
    53461 tgtattaaag tatacagttc cattacttga attattttgg ttagctaatg ctaataattc
    53521 agaattagaa taataatctt tatgctcttt tggttctaaa aacccataaa ctctatttcc
    53581 actagaatct aaaatttgca accacaattg attttctcga agttttttta atccagactg
    53641 ttttacttgt ggcttattat ctataaatac gatttgttca ttaaagtttt ctgtaaattt
    53701 tttcggccag tcactacgaa taaattcccc atttggtttc tgaatagtaa taagtgataa
    53761 gaaaatacct attactgtca ggattaagca aataaaaatc atgaaaaaaa taatgtatga
    53821 atgaaatact gttttataac taggtttatg catttaatca actcttttct taaactttta
    53881 ttttgattgt tgcttatata aaatagacaa taattattga tatgtaaaaa tttatttaaa
    53941 aatacaacta tctacataaa ttatatttat ataattatat gttatcaagc tgtctgttgt
    54001 atttaataaa tccttttgat aacatataaa agtaagataa atttttccat taaatacctt
    54061 ataattatac acaaaatctc tatatacgtt aaacagtata gagaaaattt tcatagaacc
    54121 atctttatag gggatacttt ataaaagaat aaaaaaatta taatatataa aaacttcata
    54181 ggagtgtaac aacatcagta aagatatgaa aacactatat aaaaattcaa aaatattaag
    54241 aataatgaaa tacttgaaat tgcttatatc aagaaatttt atataatata aactggtcaa
    54301 atatgttata atattaaatt gtgacaagtt catggaggtg tttatatgaa aaaacaaaag
    54361 tcgccaattt tacttgaaat gcttggacta ttttttggtt gtatatcaat gagtattggt
    54421 ataaatatgt ttttaaaacc acatacaatt gctcctggag gacttagtgg tctatcatta
    54481 gtactaaaca aggttacagg acttccagta tcagctatca tgttaattat aggtgtccca
    54541 ttagtaatac ttgcttttag aattatgggt acaaaaaatt cattaaaaac tttatttgga
    54601 acagttgtat tttcagctat agttcaatta acagacccat tatcaaaact aagatttact
    54661 aatgacttat tattgtcttc tattgcagga ggaatcctag ttggtatagg tttaggaata
    54721 atgtttaaat cagatgcttc tactggagga acagacttaa ttgcactcat acttagtaag
    54781 aaattcccag gaataaaagc tacaaaattc atgtcatgcc tagatggaat ggttgttata
    54841 tcttctggta tagtaaatcg tagtttagaa actgctcttt actctggtat agcactttgt
    54901 gtattaataa aaatagcaga tatgataatg gaaggatttg accattcaaa agcatttttt
    54961 attatctctg atgagcctga aagtttaaga caagctataa ctgaagaact tgatagaggt
    55021 cttactattc ttgatggtaa aggtggatac actagagaaa ataaagaagt tctattagtc
    55081 gtagtttcta aaaaacaaga actttatcta aagagattag ttaaaagaac tgaccctact
    55141 gcatttgtta ttgttacaga tgtacatgag gttcttggag aaggatttaa aaatttagag
    55201 aactaataaa aattaatatt ttaagtatat atactatttt aattaaaata cgatttattc
    55261 aaaaagagtg tctcataaac tttttagttc atgagacact cttttttgta taaaatcaaa
    55321 tgcattttca gtattttaac aataaaaaca ggattatcta tattttgagg caaccacttt
    55381 attgaaattt tatttagaaa acaatcatta ctaaataacc agcatagata ttaaatgatt
    55441 atatctattg ttttttcaat tcatattgat aacaaggaac attttttaca gtatttccag
    55501 tatgaatttt tttgatatac tttcctgtac atttaaatcc taataaatct aatgattttg
    55561 tagaattttg gttttcttca taggttattg caattatttt atttaagttt agttctctaa
    55621 atccatactg tattactctt tttgttatct cagtagcaaa atcatgtccc caatagcttg
    55681 gatttataca tatacctatt tctgcttcta atgctttagg atttatatta ttaaacccca
    55741 tatttccaat aactttattg tctcttttat atactatagc aaagtggcca attttccctt
    55801 ttttatatgg atttagaaaa aatgatttta taaactttct tgtatcttct aaagatttat
    55861 gctcactaaa tggtaaatgt tttactacta ttttattttt ataacagtca aaaaaatctt
    55921 caacatcatc taatgatgca ggtcttagta tacaacttct agtttctaag gttttcattt
    55981 gaggatattc agaatcagac atttctaatc cccctttata cattaatcta aatatactgt
    56041 tcatatttaa aatacgatat taattatata aatgttctca aattaacctt atttttattt
    56101 ttaataaaaa ctaattacta tatgaatctt tcaaatttac gaatttatct ctatttttat
    56161 attaaattac ttgtgaaata tgtattctaa attatatatt attagatatc atgcttaaaa
    56221 attctttggt tgctaaggat aaagatatat cttttaaatg gcagtaacct atatttctct
    56281 taggtattgg ctcttttata tctaatttaa acaatttctc attttccaaa taatctatgc
    56341 taaattcttc tataacacaa gacactccaa gatttatata cgcaaattct aaaagtaatt
    56401 catgagaacc caattctata tctgggttta gttttatacc ttttgataaa aaatattcat
    56461 ttacataaag tcttgaattt gctttatttt ctagcattat taaaggcaat gtgtttaatt
    56521 cttccaatga tattttccta cctttgtatt ctatgtaatc atttgcacat acaaatatat
    56581 catgtatttc aatacactca acaatattta gtgtatcatc ttctattggc atgtttataa
    56641 ttgctatatc tatattccca tctttgagta aagatataag ttctctactc gttctattta
    56701 ttgtagatac atgtatatgt ggatacttct tatgaaaaat ttctaaatat tttaacaaga
    56761 aaaaacgtgc agctgtatct cctactccta ttttcagaga accgtattct aattttttaa
    56821 atttatttat tctatcttct cctgatgata ttaactttaa tgcagtagtg acatgttcac
    56881 ttagaatttt cccctctgga gttaatttta ctcccttatt gtttctataa aataataaag
    56941 tatctaattg ttcttctaat tgctttattg actggcttac agctggctgt gacataaaca
    57001 attccttagc agcaagagaa aaactcttat tatttacaac tgcattaaaa accttataaa
    57061 gttcaagttt tatattcata tataattact ccttatgtca aatattagta ttatttattt
    57121 tacttataat tatatttgaa ttataatata catggtacta atatgacaat attaattctt
    57181 taggaggatt ttagataatg gatagattag ttggaactgt ttcaagaggg gttagagcac
    57241 ctattataag acaaggagat gacttagtta aaatagttgt tgattctgtt ttaaatgcgt
    57301 caaaaagtga aaactttgaa gttagggaca aagatgtaat tgccgttaca gaagctgttg
    57361 tagctagagc acagggaaat tatgctcacg ttgacaatat tgcaaaagat gtaaaagata
    57421 aatttggaga tgatactgtt ggggttatat tcccaatttt aagtagaaat cgttttgcta
    57481 tatgtttaaa aggaattgca aaaggatgta gaaaagtcgt attaatgtta agctaccctt
    57541 ctgatgaagt tggaaatcac ttaataagta ttgatgaact tgatgataag ggaataaatc
    57601 cttggtcaga tgttttaaca gaagaaaaat acagagaact atttggatat aacaagcata
    57661 catttactgg tgtagattat gttgattatt ataagaattt aatcaaggat tgtggtgcag
    57721 aggtagaaat agtatttgca aacaatccaa aaactattct taactataca acaagtattt
    57781 taacttgtga tatacataca agacaaagaa caaagagaat tttaagacaa aatggagcta
    57841 aaaaagtata ttcacttgat gatataatga cagcaagtgt agatggtagt ggttacaatg
    57901 accagtatgg acttttaggt tcaaacaaag ctacagaaga aacagtaaaa ttattcccta
    57961 taaattgtga tgaagttgta aacaaaatcc aaggtaatat aaaagaaata acagggaaag
    58021 atgtagaagt aatggtttat ggagatggag cttttaaaga ccctgtaggt aaaatatggg
    58081 aattagctga cccagtagta tctcctgctt atacaaaagg gctagaggga actccaaacg
    58141 aagtaaaatt aaaatactta gcagataatg attttgctga cttatctggt gatgagttaa
    58201 aagaagcaat ttcaaaatac atagttgaaa aagataataa atctgatgat ttaacaggaa
    58261 acatggtttc tcaaggtact actccaagaa gattaacaga ccttataggt tctttagcag
    58321 atttaacatc tggaagtgga gataagggta ctcctattat ttacatacaa ggatatttcg
    58381 ataactatac aaaatagtat gttttaataa gatttaattt ttttggatta tatatattaa
    58441 catgaaaatt tattaaaacc tcttaataga tatgactttt caagagttat atttattaag
    58501 aggtttattt aatgttcaca gataagatat atttaaataa tttaaacaag attgtcagaa
    58561 agttatataa tcttaaaaat ttatataact ctaattctta tttatttctg aaataatatc
    58621 actcttcaaa atttgtctta ctggaataat tacagcaact atactaatag tgatatttaa
    58681 aataatcata cctatgtata gaggtgtatt tattttaaga attggattta tatataaata
    58741 tacacgtttt accataaaat aaatcataaa ttgtccaata acacttccaa ttaccattat
    58801 aatacttgca tagaatccat ataaaaaacc ttctcttatc atcataagta aaaacttatt
    58861 atccgtaata cccatagatc ttaaaattcc aaactcatgt cttcttgaaa aaattaagta
    58921 gcttactgta ttgattatat ggaacaaact tattgcaaga agtacaaata caataccata
    58981 tataaataag agtttttgat ttaagtaggt attatttttt tcaatagcaa tggtataatc
    59041 tgttacgata catcttttta catcacttac aacacttttt atgttctcag acaattcctc
    59101 actgttacta tcttctgtct tttttatact tactgaatta taattttcga tatcaaagtt
    59161 atttttcatt tgcccattcg tcataactat atccatacca taatcaccaa tgaaatatat
    59221 gttatttgcc atcacacgtt ttacagtagc agcaactaca aattcttttg ttgtataatc
    59281 attcttattt tcttctttaa atttaacaat ttcatctgtt ggtttcattg tctttggcac
    59341 tttaactttt attgtatctc ctggatttat atcaactgca tcatacatcc cagttccatc
    59401 cataggtagt ctaactataa ccttattatt tttaaccata tcatgggtat taatctcccc
    59461 atctataata taagaattta atccttctaa cataccattg ttataaccat aaatatttgt
    59521 ttttaaaaga tagccacctt cattttgctt tgtacaaata ccatcaaaaa aagtctttat
    59581 cctgtaatct ttttcaagag gtttaaagaa atttttccaa aatagttgtt cttctttaat
    59641 ttgcatagct ccaaataaat atcttactgg atagactttt gatattccct caacattgtt
    59701 taatcttgaa attttatctt ttggtatacc tacatcaaaa tctgttgttt gcatagttat
    59761 ttggtagtca gaatttaaac catcatcagc tttcattgta agttcattat tatttttagt
    59821 aagctgtata gagtaactag aacatagaaa tataattcca ccaagtgata atgaaaacaa
    59881 aattccaata aacattccct ttttttgagt catgtattta tgagataata cttttgtcat
    59941 gttagagtgt tttacacttt ctaatattct atttttctta ttagtaatct taaagttttt
    60001 catagattct atactagaat atttattcaa ctgatgtaca acacgtacag caattaaaat
    60061 taacaacaat aagataaata aaaagcctag ataaatagat ttttcactta taaaaaatgc
    60121 tcctggaaca atatcactac tcaaaaatat atgtggaaat tgttcatata ttgtagacgc
    60181 tactccaata cctaagaagc aacctatagg aaatccaaca ataaaaagta aaaataactc
    60241 taaaaatagt agaaataaaa gttgtttatt attagcgcct aatacttcta aaaccccata
    60301 ttgtgatatt ctctgaagta ttgaaacatg gaaaatacta tatactgctg ctgcaccaaa
    60361 cactccaaca agcaatataa ttgcatttgt atttagttct aaatttttta agaactcaaa
    60421 tatattatat ttttctatat tttttggtgg ttttactcca aattcaactg aaagaggcca
    60481 gtttatataa gttttttctt ttgatatatt gaattttttc ataaatttat aattttgctt
    60541 tttaatattt ttattttcat catattttac ataaactata taagaatcct tttctttagg
    60601 ctgaaaataa tcgtttacaa atccctccag agcagtttct gggtttgaaa gacttgataa
    60661 aataccacat aacttataga ttttaccatc taaattgatt tctgttccaa tttctttgtt
    60721 tacatttaaa ttgtttagag aatatgtgtc aagtactatc tctccatctt tactaggaag
    60781 agttcctttt aataattttc tacctgtcat atctaaatat gaagaatcag catttaaaaa
    60841 ttctataata aaaggttcat ctatctgatt tttaggtttt gtaacgccaa gtctatctac
    60901 agtgtattcc tttgattttt tattttcttt aattttatta agttgttcct tatctacttt
    60961 atagaaataa tgataatctc cactatcttc ccttatcttt tcaattctac ttttgtctgc
    61021 actatgaact aaagaaccaa ttcccgtcaa taatgctact gatagtacta tgcttaaaac
    61081 tatagatata gattgttttt tataatgctt tatatattga attgaaaatt ttactagaga
    61141 catcatagta cttcaccacc agtattcacc acaattccat cttcaatatg gataattgag
    61201 tcgcatactt gtgctatatt ttcattgtgt gttaccataa gtatcgtttg atggaatttt
    61261 gcactacttt cttttaataa acataccact tccattgtag ttttactatc gagatttcct
    61321 gttggttcat ctgctaatat aagcgcaggt ttatttgcca aagctctagc aattgctacc
    61381 ctctgttgtt gaccaccaga tagttcactt ggaaatttta aacgcttatc ccaaattccc
    61441 aatgtcttca tcagcatttc aatatattca tggtctatat ggtttccttt atctaatgta
    61501 acaggaagag ctatattatc ataagtgttt aatacgggca ttaaactgta gttttgaaat
    61561 ataaatccta tatttcttct tctaaatact gtcaaatctt tttttcctat tttagatatg
    61621 ttctttcctt taattattac atcacctgaa gttggattat ctaatccacc tataatattt
    61681 aacaatgtgc tttttccaga accagaagtt ccaactatag cagtaaatgt atctcgttca
    61741 atttctatac ttactccatt tagggctttt actttagtct caccttttcc atagtgtttt
    61801 actaaattat tcgtcactaa tatactcatt taatttctcc tttcaataca gatatatgtt
    61861 ctataaaata ttgtaagtga cgataattac actcatccta caaaattagt ttaaactctt
    61921 acaattctgt aagaagatac taaaacaaca tccacttcct agtttagatt ctactataat
    61981 gtttccattt tctttttcta aaattaatct tgtaagatat agaccaatcc ctgtgccatt
    62041 ttggttttcc acatttttac ttctgtaaaa tcttttaaaa atatcattta gttctctact
    62101 atcaatacct attccctcat ctttaatagt aatcttcgta tatagttcca tttttattac
    62161 agaaatagta atcgtgctat ctgatggtga gtattttatt gcattttcta aaacatttac
    62221 aattgcttct atagtccact ttttattatg aactaatttt atgtctgaaa atggttcgag
    62281 atttatcctt atatttttag cttctgcttt attaaagata gtactgatac tttgaataag
    62341 agtatcttta attagtagtt cttctacttc aaattctata actccatcct ctaatttagt
    62401 cattttaaat aaggattgta acagccagtc aatcttaaaa gtttcatttt tcatcttttg
    62461 taaaaactcc ttcttctgta atgtggaaat atttatattc tccagaagtt cacaataaat
    62521 ggttatattt gaaagtggag tttttaattg atgtgacata tttgatatta aacctttaat
    62581 agcttctttt tctgactttg actgttctac ctctatttct atcatatcct taattttttt
    62641 tacttggtga gaaatttttg acgctcttgt atcctttgta tctggataag taacttcttt
    62701 accttccaat atttgattta acatcaaatt taattcatca tatctttttt gatttatttt
    62761 agtagatact ataaatataa caactgtaca tattataaag gctaatataa acatattatt
    62821 ctacctcatt ccataaataa cccattccat aagctgtttt tatatatttt ggattagatg
    62881 ggtcatcctc tacttttact ctaagtcttc ttatatttac agatacaata ttatcatcaa
    62941 cataattttc ttcgctgtcc caaatatggt gtaaaatttg ttcctttaat aatatttgac
    63001 ctttattttc gattagataa cttagaagct tatattctac agagctaagt tccaaacatt
    63061 ttttattttt atatactttt agtaactttt ggtccaattt tattccattg gaatatatta
    63121 ctttattatt cgattttttt cttattgcta ctttgactct tgcctttaat acagataaag
    63181 aaaatggttt tgtaatataa tcatcaagcc ctatttctaa tccttttact tcatcaattt
    63241 ctgagtctct tgcagtaagc attataattg gtatatctga cttttccctt attatttgac
    63301 atacatcaaa tccatctcca tctggaagat tgcagtctaa gattataaaa tctatatttt
    63361 tactattaaa tatatttaat ccttcttgtt ttgtataagc cttaaataca ttaaatccat
    63421 cattctcaaa tgcataaaaa agaccttcat ttaagtttat atcatcttca ataattaata
    63481 agttcaattt tactctcctt tagatttttt agataaataa ttattttctt gcattatcat
    63541 actaaaaata ttttaatttt atttatttca ctaaaaagat tgtatttaaa tttgttttca
    63601 aaataaaaac atcataatca agcatatagt tatatatttc ccaatttaat tacgcttaaa
    63661 ttgaaaatat aactttattc ttatataatt aaattataca acaataaagt tatatttttt
    63721 aaatatattt ttactagggg gaatagaatt gaaaagggtt gatgagagaa atactatgtt
    63781 tgcaagagca aattacaaaa aagatagtac tgcttataat gactattata agaaaaatcc
    63841 tgacaaaaaa gaaattgatg atagtataag aaatagacca aatttatgta gtgaaggaac
    63901 aatgacttac aatgagttaa actctccaat ggcaagtagt gcattcgatt ttttatctga
    63961 tatcaaatct ttatgcgaag gaaaagtttc tgatactaaa gtagatgtag atgcaaagtc
    64021 aatgacaaaa aaaattaagg gtcttgcaaa gcagtatgga gcttctgtag ttggtataac
    64081 taaattaaaa gactatcata tttatacaaa taggggtaga catgaagaaa attacggtga
    64141 agaaattaat ctaactcata agtatgcaat tgtatttgga tgtgagatgg ataaagaaat
    64201 gataaataga gctccaatga tatgtgaagt tatagaaaca tcaaagtgct atgtggatgc
    64261 atctatcgtc ggcatgattt taagttacta tataagaaat ttaggatatg atgctagaaa
    64321 tcatatggat gctaattatt tagtaatgcc tgtttttata gctcgtgatg cgggtttagg
    64381 agatatagga agaaatgcta tacttacgaa taaagattat ggctctagac ttagattagg
    64441 tgttgttact acagatattc ctcttttaga agatgaatat gttgattttg gactagaaga
    64501 tttttgtaag gtctgtaaaa aatgctcttt taactgccct tctcattcgc tttctaatga
    64561 tattaaaatt ggtgatgatg gaaaatataa ttgggtaatt gaacatgaga catgctatat
    64621 taaatggaga tatttaggta cagattgtgg tatgtgtata tctgcttgcc catttagcca
    64681 aaatctcgaa actataaaga atactacttc atttaagggt aataatgagc ttattcaaaa
    64741 agctttagat gagtatactt caaaatttgg taaaagaata tttatacctg gaaatccatc
    64801 ttggttgaaa taattttatt taataaagaa tctgtactag aatttatcat aggacaggtt
    64861 ctttattaaa tatataaatt tttaaatact ttttctcgtt tataacaatt cagcaatgtt
    64921 tttagtctat aattgacatt ataaaatatt aaactaaaag gagtaactgt atggaaaaaa
    64981 tattagtagt agaagatgat tctatattaa ataaaactct atcatataac ctaattgaag
    65041 atggatatat aattacttca aaatttacag ctaaatctgc actgaagtct atttttgaat
    65101 gtgaatttga tttaataatt ttggatatta atttaccaga taaaagtggg tttgaattat
    65161 gtaatgaaat aaagggaaat tacaatatac caataatttt tttaactgct aatgatatgg
    65221 aatgtgatat gattaaaggc tatgaacttg gagctttgga ttatataaca aaaccattta
    65281 atatcaatat atttaaacaa aaaattaaag cttttttaaa tcatcttaca ataaaaacaa
    65341 aacaagatta ctatagggat ggatatcttg aaattaactt ttctgagtta tctgccaata
    65401 taaatggaaa tcaaattata tttacaccat tagaatatcg tactttaaaa ctgcttactg
    65461 aaaatcctaa aagtatttta acaaggaaag tacttttaga aaaactctgg gatatagatg
    65521 ctaactttgt agatgaacat actttaacat ctgttataag taggattaga agcaaaattg
    65581 aaaaagacaa tcttaagtat atcaaaacgg tatatggtat gggatatatg tggttaggtg
    65641 aaagaaatga attttaaaaa attttctttt agttctattt atttaataat tgctgttggt
    65701 ataattttta cagctatttt atttagtatc tcaatttatc taataactgg tgatttaaaa
    65761 ctaattgctc tattattaat atatacaatg gtactttgtg gatttatagc attaataata
    65821 tttttacttc ataaaaaaat agttatattt tgttataaaa tatgtcacac tttagatagt
    65881 atgatgaata gtgaagacaa tattgaaatt gaattagaag aagaaactat tttatcacgt
    65941 atcaatcaca gattaattag aatgtatgaa gttattcaag aaaatcgcaa tagtattgct
    66001 atagagaaag ctgatttaca agaattagtt tctgatatat ctcatcaaat taaaactcct
    66061 attgcaaatt taaaaatgat taatactact ctactaaatc aaacatttaa aacagaaatt
    66121 caaaaggatt ttttaatgga tatggaaaac caattagata aattagattt tttaatgcaa
    66181 tctatgataa aaacctccag actagagaca ggtataatca cactatctaa aaagaaaaat
    66241 tcaatttatg aaacaattgc tacagcactt agtggaattt tgtttgatgc tgaaaaaaag
    66301 aatattgaag ttacagttga ttgtgaccca aatttatata taattcatga caagaaatgg
    66361 acttctgaag ctatttttaa tatattagat aatgctttaa aatacacaaa ttctaatggt
    66421 aaaatacgtg tagctacaga atgttgggtt atgtatacaa aaatagatat tattgataat
    66481 ggaaaaggaa tatcagaaag tcatcaagca gaaatcttta aaagatttta tcgtgaagaa
    66541 gatgtccatg acatagaagg tattggaata ggtctctatc tttcaagaaa aattatatct
    66601 cttcaaggtg gctatattaa agttacatca gatattggaa aagggtcgac tttttctatt
    66661 ttcttaccta ataaataaat ttttaaatat ttcatttgta atgattctgc aacattttgg
    66721 ttttatactg tatttacaag atgttaagga ggtattatta tgagtatttt acaagtaatt
    66781 aatttaaaga aatattatgg acaaagttca aacattacaa aagctcttga tggtgtaact
    66841 ctatctattg aaaaaggcga atttatttct attgtaggta catctggtag tggcaaatcc
    66901 acattattaa atatgatggg aggattagat aatcctacat ctggaaaggt tattataaag
    66961 ggtaaggaat tatctactat gactgatgaa cagcttacaa tctttagacg cagaaatata
    67021 ggttttatat ttcaaaatta taatcttgtt cctttactta atgtatatga aaatattatc
    67081 ttaccaatag gattggatgg agagaccata gataaggatt ttataaatga aattataaat
    67141 atgctttctc ttgaagaaaa attatatgat atgccaagta atctttctgg tggtcaacag
    67201 caacgtgttg ctatagctag agcacttgta acaaaaccag ctattatact agctgatgaa
    67261 ccaacaggta accttgatag tagaactagt tcagatgtac tgagtttact taaagtgaca
    67321 agtaaaaaat tcaaccaaac aattgtaatg attacacaca ataatgaaat tgcacaacta
    67381 actgatagaa ttattcgtat tgaagatgga aaaattgtta actaggaggt gtagtatatg
    67441 tttagaaata ataatcgcac atttataaga aaaatagctt taaatgattt aaaaattaat
    67501 aaacttaaaa catatctttc aggtatcatt ataatgattt ctacatgttt attattaaca
    67561 gtgaccttag tttcatataa tgcttctgta gatttagtta atgcatctcc atatcatgct
    67621 atatataaat ctgtagatga aaaagcaaaa aatatactat ataaagataa aaactttagt
    67681 ggcgtaggaa cttacaaatt aattggaagt aataaaaaga cagattgtat tatgtcgatt
    67741 gtttatgcag atgatacagc aattaaactt atgaattttc aaccattgaa aggcaaacta
    67801 cctacaaata aaaatgaaat tgctatttca gaaaaatatt tacaggaatt tggtttagat
    67861 aaagatattg gagatagcat taaattaaat tattatgatg atattacgaa taaagaagtt
    67921 caatgtgatt ttattattgt tggatttcta gaaaattatt atcaagataa tgccaagcaa
    67981 tactatacag tcgtttcaaa tgattatttt aagaatatag cttctacacc tttacaaaat
    68041 aaaagtaata cttttgacga gttaagacct gatactgtag atgtattagt taaactatca
    68101 gaagaaaata cagagaaaga ttcagcttca attaagacac agttaaataa aattggttta
    68161 tctttaggta ttaagaaata taatatatac ttaaatgata actatattga atcaaattta
    68221 attgatggtg agcagattat tacagtttta gtagttggaa tagttgttct tttttctagc
    68281 gtttttgtta tatatagtat tttttatatt tcagttgtta attcagttca gatgtatgct
    68341 aagttgaaat cgttaggtat gacttctttt cagttaaaaa agattatttc tctacaagga
    68401 aatattttgt caattatttt tattccatta ggggttatag cttcttgtat aattgcttac
    68461 ataattcaac cattagcatg gcaaatgata gctgatttat ttataatttt aattttatca
    68521 ctggtaatgt ttttaactgt tagaatttct ttatttaaac cagctagaat tatttctaaa
    68581 atatctgcta ttgaagccat gcaatataca gaaactaaat ttagaaaaaa agcaaaaaat
    68641 tttagttata taaatataaa aaatctagca ttaaagaata tcgagtcaaa tagaaagaaa
    68701 aatttgattg cattaatatc gctaagcatt agtggagttt tatttatttc aatcgctaat
    68761 cttgctaatt caatagattt caaaaaacaa ctatctcaac aatttgtcta taacgaagat
    68821 tatataatta gcattaagag tgataactta tatgagcata ttacagaaat ccaacaaaat
    68881 aatccactaa cagattctct taagaatgaa attaaatcta ttcatggagt aaaaaaatta
    68941 attgaatcca aatcaattaa aagtaatatt atagaacctt acatcaaaga tagagacgaa
    69001 aaacaattta ttactctaat taaaggtatt acgcctgaac tttcaaaatc acttgaagaa
    69061 tatattgtca gtggaaaaat agactataca catttagatt cagatagttt aattataaat
    69121 aaatatagaa caaaatctta tggattaaat ttaaaagttg gagatacagt tacatttaat
    69181 atctttagtg gaaatgatat tattaaaaag aaaatgaaaa ttataggaat cattgacaat
    69241 tccaatacag gaggtatgtt ttttgcttca gacaaaactt tagaatctct aacaccatat
    69301 aatacaaatt tagatttttc tattttaata gataaaaagc attctaaaga agttgaagaa
    69361 aagttgttaa gtataattca gaaaaattca aatttaatgc tttattcata tgaagatgat
    69421 tatagaatga ttactagaac atttcaatat ataattatag cttcatacat ttttgttggt
    69481 ttaatttctt gctttggtat actaaatatg accaataccc taataaacag cgttttaatt
    69541 agaaaaaaag agtttgcctt acttcaagcc gttggaatga caagaaagca actgcgaaat
    69601 atgctttata gagaaggtct aaacataagt atcaaagcta tatgtacttc aagtatacta
    69661 ggttattttg gttcaaatct actttgcact tttataaaag atgtaattag attagacttt
    69721 attaatttta aattttctat atttactatt ttaatttttt cattcgtatt aattggtata
    69781 caagttttag tgactgaatt acttgtaaga aatatagaaa aaaaatcact tacagaacgc
    69841 ttacgttctc agtaagaatg tatataaaaa atagccattt tttatacaag ttttgatatg
    69901 attttttaaa agctaaaggg atagaaaatt ttgactttac ataattttct atccctatac
    69961 ttgtttttat tttatacaga tacacttcct tatatctccg agcaacatca ccagagacat
    70021 aaacaagcat attccttatt ttctaaatat gtcaattgca tgacttgtaa cccctactaa
    70081 atcttcacgt tcacaagtag caaggtgata ttttaaatat aatgcaaatg catcatcatc
    70141 catagagtct actgcttcac gcatatataa agccaaacca tctgatgcga cataatgcag
    70201 tctagttaca ttaaatgcag acatcaaatc atcaatgttt tctttacgta caagctcaaa
    70261 caaatccttt ggttcagact tagcagcaaa tgtctgtgga tcaatcaaac ctttttcaat
    70321 atattcagat acattaatat ttcctctatg gaacccctcg tcaatgagac agccatcaga
    70381 tataacatat gcagcaaaaa ccacaccacc aggttttgtt acacgaattg cctcatgtaa
    70441 agcttgttgt ttatcttctt tgttataaag atgatatagt ggtcctaaca gtaacgtaat
    70501 atcatattta ttatctggga aaacagataa atccatagca ttaccctgag taatgcttat
    70561 attttcattt gattgagtat ttttatagaa aacctctata ttatgttcga ctaattccac
    70621 tgcgtcaaca tcatatccct gacgtgccag tgtgtgagaa taacgaccag ttgcagcgcc
    70681 aatttcaagc acacaatcac ctgattttat gtacttatca atgtaatgca tagtagtgag
    70741 aaattccacc attccatgtt ttaatgcaag tcgactatct tcatcataag tattataaaa
    70801 gtcaattaag tattgttttg tttccataat ttcacctctt ctatattagt taataaacat
    70861 caaatagaca aattccaatc tggtttttct tgtcttataa aagctgttaa tatatttttc
    70921 aacatttttt cagcactata tctatctaat gttagttttt ttgttgctgt taagacagct
    70981 atgccatgag tataaagaaa taaatctaaa aatattactt ttgcacattc caactctatt
    71041 ccaatgcttt ccgaaaaaag tcttgccttt ttttcattgt caatttcttt ataaaaatca
    71101 ttcgcctctt tcatcatcaa atctaaatca tttataaata acaacttaaa taaatacgtt
    71161 tcttcttgag caaattcaat gtatgaaagc ggaagcagta aataagggct tacactttta
    71221 gaattacgat aattaacaac atactgatta taatattcat atgcaaaagc aagaaattca
    71281 ttttttaatt cattcatgtt ttcataacaa gtaaaaattg gtcgagtgga acactgtaat
    71341 ttacttgcaa tactcctcgc atttacagct tcaaatccca cttctcttgt aatatccaag
    71401 actgtattca aaatcatttc ttttgttatc tttactttag gtggcatata tgttcacctc
    71461 tccattaaat ttttataaaa cacatatgtt atataactat agtaacatat caagaaatta
    71521 tgtcaagaaa aagctttgca tttttttgca attcctaaaa cttataaata aaacatgagt
    71581 tgcaattaat ctattaatag ataacagcaa ctcagatttt cctttaaata ctcttctttt
    71641 tgtctaatat ttcatataca caatcttcta ttgaattaat atctttttct tttctttttt
    71701 tagaatcaat taaaatgaaa tacagtataa aacctacagc aagtccccat gttccgcctt
    71761 tagcagtaat tacacctccc ataagtccaa tcaatccctt ctcaacacct gtattacata
    71821 gctccattga tagctttgta cataaatatc cttgaactaa aagtgttact gacaatgcta
    71881 atggtataag aggtgtagca atctgcgcaa ttggataaaa acagataaaa attgctgaaa
    71941 cccatactaa tgtacccatg ccactaaaaa cagactgcat ggcttccttt ccaaccttgt
    72001 acctttgagc aacacttcct gtaagtgtcg cagctaatgg accgcacatt ggtatatatg
    72061 gagaaaagat tgccataaaa atatttctta tcccacttat aacattagac ctatttgaat
    72121 tgaaatctat atattcatct tttctatttt cactttcaga aagtactaag ttttcacctg
    72181 ttataaaatc accaaaggca attatgtata tcataaaagc cattggtatc ccttgtataa
    72241 ataacattac acttggaaaa cctattccaa aaggagatac tgtatttatc agatttttaa
    72301 aatctactat gtaaactaaa ttgtcaaaac taaatctagg aatttctatt tctttactaa
    72361 atatacctac tattaaactc actaaaatag ctgatactac accatattct cctaaatgaa
    72421 ataaaaattt attcttaact tttagagtat caaatctttc agaaaacatt acaaaacaag
    72481 caaccaaaat tcctactgtt atagatatag gataagaatc aaatctccct ttaggattaa
    72541 actctgatat tatagtcgat ataccgacac ccattagtat tccaccttta atagaatttg
    72601 gtatcttact aactaacttt ccagctacac cagttatacc cattaaaata aatattattc
    72661 ctaaatctat ttgtaaagct gttaatgctt gtattctttc aatgcccatg ctgaacttta
    72721 acaaatatgc agttgtaaga gttatagaag ctgtaatcca gccaggtaca actgggtctc
    72781 ccataaaaac atgcaaacag tataatattg agttaatgat agccatactc catgccactt
    72841 catagggtaa tcccaaaatt tgtgtactaa ggccaattgt gcctaaactt gtcatacttg
    72901 atattatacc ttgaatagct tctggttttt caaatctgta atgtataaat ggaattctta
    72961 tcttaaacat tccaaatttt atatgaggtt gttcccttct agcgagtctt tccataactt
    73021 cactccacct ttcaataact cttataagtt tacaacttta taattgttta taaattatca
    73081 atgtcattaa aattagtata taacatgcaa attatataaa caataaatta aatctataaa
    73141 attgatagat tttgtgcata tatagaaaga ccgcttcatt tttagttact taaatcactt
    73201 aatattagtt atttaaatca cttgataaag gttttttata aaattcaata gttctattcc
    73261 ataattcaaa ctgtcctttt gaatttcctt ctacagttcc acctgaagaa aaaatccctc
    73321 cactcatact catacataaa gtctccttta gaggcataat atatggaatt ggtaacggat
    73381 gacccatatt attgtatgtt aataattcta cgttatatgg ataattattt tcttcaaaga
    73441 tttctaatgc ctttaaacaa gcttcataac tattccatat gttatcttct tttccagcaa
    73501 tcataagtat atctgctttg gaattttcta tttttattct agcctctttt ctattctctg
    73561 ctcttttaag acttttctta taagtactat taaatccaaa tggaatacct tttgatatat
    73621 tttttttctg ttcttcaaag aatatatcat tgtctacttt gatatatgga aatggctctc
    73681 ctttatatga ccatgatgaa gtatcatttc cactcatcaa tccattaaga gcttggaaac
    73741 aataaatgtg aggttgtgat actacaacct ttttaatttg ttcatatctt gaagcaagta
    73801 aaaaggccaa ttctccaccc tttgatgtcc catgtacaaa tatttcttta gtactggtaa
    73861 tttcattttc actaatccac tcaaatactt tttcaaaata ttctaatgga acctcttcta
    73921 atttatctgg taacccttct aaagcaaagt atgcaactgt tagtacattg aatcctctag
    73981 atgcaagtgg agctgctaaa aggtctagag cgtctaaatt tccatcagaa ccacctagca
    74041 ttaaaattgt tttattatta gaattttgtt tataaaataa ttttcctata aactcatcag
    74101 atatgtattt tgtggtaata tcttctgatt taaatattct ctttaattca acttcttttc
    74161 tttcaataga agtttcaaat atcatattca taattattgg tttatcaata gatatatttt
    74221 ctgcaaaatt tttaccttca gttttagatt tttccagcga ataaattaac cccatacaat
    74281 tatcagcctt ataagtacct tctataggtt caactaaatc taaatctact tctccttttt
    74341 catttgaaca aaacactcca taagatgaaa attcttctcc cttgcaccat ggaaattcca
    74401 ttttcacact tattttaagt ttagtatttg gaattaagtc cgaaaccata atcttaagtc
    74461 tttcatccac aaatgattct acattgtata catttacttt cataatctat ttctccttat
    74521 aataattatt tatgttttat ataaaacaga tttatctaat gcaacataaa taaattttta
    74581 aattaagaca ccatattgac tatttcattt tatcaacata ttccatcttt gtcaacatat
    74641 tgtctttttt agtaatttaa aattatgtag tctatatgaa atccagttga tttttggcta
    74701 attaaagata ggaatgctat taggtttaaa atatatctat tcaaaataaa aaaccactca
    74761 ttttaagaat ggtttttaat ataaactatt tgttattaat aaggatattt ttttatttaa
    74821 atttatataa tcgaacatct aatatttaat gtttaataaa attatgcatt tgcaaaagta
    74881 tatatggcat taactcttgc tacatataaa ttctcatcac tacatccaat atatctagca
    74941 tatttttcaa tcttttcttt tgcattttca acatcatttt catcgctctc cattaactca
    75001 tttatataaa tatccattaa tgacgcttta tattctctta tatcatagcc taaaaattca
    75061 gtcaatctct caatttcctt actaaaatct ccatcttctt ttaccaaaaa ttcgtataca
    75121 tcttccctat atggatttaa agttattatt tgttttacta ctttgcattc gtcagccttc
    75181 ccaataaaac catctttata attattaaat aaggcattag atttttttat agattcttca
    75241 tcaatataag aatgtaccgc agttatacga ttttctataa gggcatctac aacagcataa
    75301 tgaattttaa aacaatcatt gtataaataa ttgctcattt tctttattgt cgattctatt
    75361 tctaagaagc tcgcgtggcc atttttttta tttttatttg gtataataaa agttttattc
    75421 aaattattaa aaagtctctt aaaatctaaa tatttttcac aataaacact tttaaaggta
    75481 tcgatatcta tagttataat tccaaaactt actatagtct caattccttt cttaaaagac
    75541 tcttctatat atttttctcc taaacttaaa cctctatcag atatttgctt tagattttga
    75601 aaactattta aacaatctct ttcaaagttt ttagatattt ctaaagcata taatttaaag
    75661 attttcctta tcttattata attatttttt gtatcatcaa atctgataat agctccattt
    75721 acatcaaaag taatcattga gttttaacct ccccattagt ttcatcaata aaataaattt
    75781 aatataaact ttataatcat aatattaaac ttatttatac tataattatt aatttgatga
    75841 taaaagctat tttccttcta aataaaaaat ttgtctaaag tttctaaaaa atttagacaa
    75901 atcttaggtt attactcttt aaattatttt taaattattc caaatacgcc aaataatatt
    75961 ggtataaata tagctggtaa caaattggct acttttatat tcgttaattt aagtacattt
    76021 agaccaagtc ctataattaa taaacttcca gctgctgtca tttctgtgac tacaggatca
    76081 cttaaaaatc catttaaaaa tgatgctccc acacatataa taccttcata caaaaataca
    76141 gatattgcag aaaacattac acctatacct aaagaagctg taaatataat tgaagctatt
    76201 ccatctataa cagattttac aaataaagta tcatgacttc ctgtaagacc actttctaat
    76261 gaaccaacta ctgccatggc tcctatacag aataataaac tagatgatat aaaaccctct
    76321 gctatagaat cttttttatt tcctttagaa aatttacttt gtaaaaaagc acccaactta
    76381 tttacccatt tgtcaatatc tattaattct cctatcagag cacctacagc tacggatatt
    76441 attgtcacta atgtgttttt tccttctagt gctcctgata taccaatgta caatacacat
    76501 aaagcaattc cattcattat agtatcgctt actctttgag gtaatcctcc ttttattata
    76561 agacctacta tacatccacc tgcaattgct agactatttg ctattactcc aaacattttt
    76621 tctcccctcg attagctaat tgaaatttat cctattatta aaacctaaac atctatactt
    76681 tgtattggat attttaaata ttccaaaaat tcttcaaaac cttttctaga tatatttaca
    76741 gttttagtat ttatgttagg atgaaaattt aagtaatctt ctttaattac atctttatct
    76801 atgtaaagct caacttttct ttctgtatca tttattaatg aaaaaggatt tacacttcca
    76861 ggaagaagtt taagtacatt gtatagtctt tcaggtgaag caaacgataa tctagaactt
    76921 cctatcttat ctttaagtga gtttaaatca acttgttttt ctcctttaac tacaataaga
    76981 taatacttat ttcctttggc atttcttaaa aataaatttt tacattgaca cccctttgtt
    77041 attccatcta aaatgactaa ttgctctgct gtatatacag cttcatgctc tactacatca
    77101 tattcaacat ttaatttatc caaaatatca tatattttag tttcattcat gctagattca
    77161 ttttcatctt gttctttttt attatttaaa tcactcatac ttttctcctt aaacacttca
    77221 tcataatatc attgtgaggt attattctac tatagctatt gctcttactg gagctccatc
    77281 agcatcatta tacttaaatg gtgctgctat aaatagaaat ttttctggaa cattttctaa
    77341 atttgtaaga ttttctatga ttatttttcc tttttcaaat aaaatatgat gcacttcaaa
    77401 tactgatgtg tcatatctat ccactgatag catatctatt cctatgcctt ttatattagt
    77461 attagctata tagtttgcag cttcttttgt taatgtagga taacctacat agtactgctt
    77521 tttatcccaa aattttgacc aacctgattt aaatattata aaatcactat tttttatttc
    77581 atcttcatat ttttttagat attctaattc tatattctca tttccctttt caagttccaa
    77641 tacataagct ttcccaacaa aattttctat atccaactta tctagggtct cacctttagt
    77701 atacatatgt cttggtgaat ccatatgagt tccattgtga gaaaatacac taattaatgt
    77761 ttcttgataa ccattttctt caataatagc tactttcttg atatctggtc tattaggctc
    77821 tgcatataca ggcatgtcat tatgtgtcac atgagttaaa tcaaaaacct tcatctttat
    77881 atacccccta tgtttttatt ttctattata tacctaaatt cattttattt ctatcagatt
    77941 ttattccatt atataccata ctactatata ttttttataa acctcaaggg atttaccgaa
    78001 aaatcttgga aagaattatc agtaaatata acatcttcac ccaaaaaacg tttatacctt
    78061 ccttcttctt tctttaaagt aattctctgt ttttgtgaat gattattaaa aaccattatc
    78121 ttaagaggag gtttttttct attagtctgc actcttttta acatgtattt tatgtgcata
    78181 tcagcttcag gaaatgaata tccacaaaat attaaaaggt cagtatctct taaagttttt
    78241 tctgtttcat tccaaacatt acttaaaaat atgtttgaca tattcttaaa atatgttggt
    78301 ggcactataa taggttctgt taactcacca cactctaaac attttgtctc tgaactattt
    78361 tcaataagct tcatgacacc accttcatgt ggtgtaagag ttacactatt acaaatgggg
    78421 caataaagcc aattcaatga cccatgtatc ttatataatt tgattaatgg ttcttttggt
    78481 tttctccaat ttaactcctc tttaaaattt gtaaactcca caccataatc aagcataatt
    78541 ggcaaatcat tcttatctct taatccagta actgtattgt ctatatgtat atcataattt
    78601 gcactaataa aagtagtatc aagaagcaaa tcattttcca aaagattttc aactaaaagt
    78661 ttatgatatt tattatctgt tctaggtgta ttatgaattg cttcagccat tagcagtatt
    78721 aaatattgtc ttaaaaaacg tatactatca cttctgttat ttagattttc tagtccaaaa
    78781 tttctaaatg cttcttttct ttgttctgct aagtctaaaa gacctaaaac ttcttcaaag
    78841 gtaggaaaat ttgcattatc tatattatct tttactatat caatattgaa catctgttta
    78901 aagaaaatat acaattctct attcattttg gtattataat ttgtgggatt tagtttttta
    78961 aaatattcgc taaaaagttc attttgaata ggtagattct ctgctgctga agctcctgct
    79021 cctaaaaata ttgctatttt catatagttc ctcctaatat aaatattact cctattttta
    79081 gatccattaa atatccatat catttatttt atgatacaac aataaagctg tcttttacta
    79141 gaaaaaatcc tattacaaga cagccttata ttatattaaa tctttaataa ttcgtaaata
    79201 gaaagagcat atatttgagt agcttttata atatcctcta ctattaagta ttcattagct
    79261 tggtgttctg tttctggttt tcctggaaaa atagctccaa atgcaacaca attatctaaa
    79321 gctcttgcgt atgttgctcc tccagatgaa agtggtgttc catcaagacc agtttcttct
    79381 tcatatactt ttctaagtgt cttaacaaga agagtatctt ctggaacata gattgaatcc
    79441 aagaaatcat attcttcata atttaaattg tatttatctg tcattttctt taactctttt
    79501 acaaaatcat cctttttgta tgttactgga atccttacat ctattcctgc aaattctttt
    79561 tcgttatcaa tagttactct acctatattt actgttagtt tacctgatac atcatccttg
    79621 caattaggaa ttatattgtt tccattagca tcttcaccaa taacttctgc taaaaactta
    79681 attatattag aatctatacc tatattatta agagctatac aaagtctagc cactgcattt
    79741 ataccagtat cacttgctgc tgaatggaca ctttttccaa ttatacagat tttattacct
    79801 tcaacagtat attcaaaatt taatttatca agttcttttt ttaatttatc agagtatttt
    79861 ccaatataga ttgctttacc tggaactgca tttaaagcct ttccaactga caactctata
    79921 tcacttttgc tatcacaagt caaatgaact tgtaaaagac ctttctctgc atttgttatt
    79981 gggaatctag aatctggagt aaatccatag tttggtattt cttcattatt ttctttatat
    80041 ttatttatac atctccaaag attttcttca tcagccccaa aaatgaatct tatcctctta
    80101 ttaaagtcta catttaaatc cataagagct ttcactgcat aaattgctga tattgtaggt
    80161 cctttatcat cttgtgttcc tcttccatac aatttaccat cttctaaaac agcttcaaat
    80221 ggagggtaat tccagctttc taaatcacct tctggaacca catcaacgtg accaagtata
    80281 cctatcattt tttcaccttg tcctatttct gcatatccat aatatccatc tttgtatact
    80341 gtcttaaatc ctaaagattt acataagtct aatatacctc ttaaagcttt atctacattt
    80401 tcaccaaatg gacaattttc agttgcttca gatataacac taggtatttt tacactttct
    80461 tgtattgaag aaatcatttc atcttgtaga gaatttactt tttctttaat ttgatctttc
    80521 atattatcac ccttcaattt tcatcataat atactaataa atattttgac cttttaaaaa
    80581 aaaaatatgc ttattttttc agttttttta taaattcaat cgcttttaaa gtccccattt
    80641 tcgaatggtc aaatgtaagt ccaccttgga aataaacatt ataaggaggt cttattggag
    80701 catctgcact taattctata gaagaacctt gtataaatgc tcctgctgcc attatgactt
    80761 cactttcgta tccaggcatg tcccaaggaa caggttttac ataagaatcg actggtgcag
    80821 cttcttgtat accttcacaa aaacttatta cttcatcagc attattaagt ctaatacatt
    80881 gaataatatc acttcttaag tcatcatatt ttggtaatac gtcatatcct aatttttcaa
    80941 aagctcttga gcaaaagata gctcccatta cagcctgaga tactatataa ggtgccaaga
    81001 aaaaaccctg aagtacattt ctagttgttc caaaagtaag accacattct tttcctattc
    81061 caggagaagt cattctataa gatataagct caatcaaatc ttttctacca gctatatatc
    81121 cacctgtcaa tgcaagccca ccaccaggat tttttattaa agagccagcc ataacatctg
    81181 ctccaacatc agtaggctct ttggtatcta aaaactcacc ataacaatta tcaaccatta
    81241 ctatagcttc tggtttaaca gactttatta cttctatagc ttcttttata tcactaattg
    81301 aaagtgattt tctccaagaa tatccttttg acctttgtat cataacgagt ttagttctat
    81361 catttatttt gtttttaatt ccttctaaat ctaagtttcc atcctctaaa aaatctacat
    81421 catcatatgt aacaccatac tctttcaatg aacctttttc ttctcttatg cctataactc
    81481 cctctaaagt atcatatggt ctaccagtaa cagataaaat ttcatctcct ggtctaacta
    81541 taccttgtat acataaagta agtgcatgtg taccatttac aattattggt cttacaagag
    81601 catcttctgt attaaatact ttagaataaa tttcctctat tttttcacga ccaatatcat
    81661 tatatccata tcctgtagtc cagttaaagt gcatatcact tagtttagat tcttgcatag
    81721 cttttaaaac tttatattga ttatattctc ttatttcttt tatttcttca aacttatctt
    81781 ttatatcttc cattatttct tgcgatagtt taaaagtatc atcatctatt ccatagtagt
    81841 cttttaataa ttcttttgtc tcattaagca ttttatcacc tgtctcttta ttattttatt
    81901 taaacatgta aaggagacta ttttactaaa acaaataaat tatagtttat aagttagtat
    81961 aagtctcctc tcaatcatct taaattaaat taattatcta tctgttgtta ttattattgt
    82021 tgttttggtt ttgatttgtt agattaatat actttccagg ttgtatagtt gatacagcat
    82081 gtttataaat catgttttgt tgtctattat ccccttctat taatattata taactatcaa
    82141 acccctttac aagcccttta acttgcactc cattaactaa atatatagta acaggtatcc
    82201 tttctttcct tgcattattt aaaaacaaat cttgtaaatt taaaactgta tttttcatta
    82261 gatttgtacc ctcccaagat taaattgaac ttctaaaata ttcctacctt atattctata
    82321 taagttatga caaattttca atattaagtt gtatacttaa aaatttatat attattttat
    82381 agaatcttta atatataaga ttatttcatt ttttaattcg tctatatttt catattggtc
    82441 taaatcaaac cattttgctg ttttatatct tttaaaccat gttatctgac gttttgcata
    82501 ccttctagaa tctcttttaa ttatttcaat agcttcttcg tatgtatatt ctccatccag
    82561 atactttaat atctctttat aacctatacc ttgcattgat atcatatctt ttttaaatcc
    82621 catacttaaa agttttttta cctcttcaac caatccattt ttaagcataa tatcaactct
    82681 catatttatt ctttgataca aatgttctct atctctattt agaactatta ttattggttg
    82741 atattcttca ttaaatttta aatcacttga aaaatcattc attttcttac cacttagaca
    82801 aacttcaaga gctcttatga cccttttagt attgttttta tggattctat tagcagattc
    82861 ttcatcaagt tcttttaact tattatgcat gtaatctatt cccttttcag caagctgttt
    82921 ttgaagttct tctcttaatt cattattggc atcagattgt gcaaaatcca tattatatat
    82981 taaagagttt aaataaagtc ctgtgcctcc agttactaaa acacattttt ccttttcatt
    83041 tatttcatgt atatattttt ttgctctttg ttgaaactct gaaactgaaa atggatagtc
    83101 aggcttaact tcatctataa ggtaatgctt cactccttgc atctcttcct ctgtaacttt
    83161 tgcacttcca atatccatat attcatatat ttgcatagaa tcagctgaaa ttatctctgc
    83221 attcatatct tttgctaatt ttattgacaa atctgttttt ccaacagcag ttggacctgt
    83281 aagtattata agtggtattt ttttcataac attcctttcc atatatttta aatatccaaa
    83341 tattttacat aattctttta aacatttttt ctatttctgt cttagatatt tcgaccatta
    83401 taggtcttcc atgaggacat gtaaatggat tctcacactt ttctagctgt tccaataaac
    83461 tttttatttc aatatcgtat attttatcat ttgcttttat agcagaccta catgccatag
    83521 atgcaaatct ctctcctttt aaatcataat tacttgtaat ttcttctata ttatcaatta
    83581 tttgaagtat aaatttctca gtttcaggta ctccaaatat agtaggaaca catcttacca
    83641 ttatatgatt attgccaaaa atttctagct caaaaccaaa tttcataaat aactccaagt
    83701 tattttcaat ttgaagcata tctacatttg atacttcaat aaccactggg tctaaaagta
    83761 tttgcatatt tatatcttgt ctatagaact tctccatata tctttcatat agtattcttt
    83821 catgtgcagc atgttggtcc aacaaataca tagaatcgtc tttgctcaaa attatataag
    83881 tattaaatac aactccaatt acagaatatc cgtataaaga aaacttgcgt tttgaactac
    83941 acgagtattc ttcttcactg tccttaatac tatctcctaa gtaataattt ccttcatttt
    84001 taattccatc aacttgaaac tcttcttgta tattatcatt tgcactatct tcacttagat
    84061 aattaatgtt ttttacatca tcttctacac ttgcatttag gacttcactt actgattgaa
    84121 attcatttat tggtttttca cttgataaag taacaacttc aatgacttca tccttacctt
    84181 tagtaatatt actattttta ggagtagatt ctaataaatc attatttctt aatttataat
    84241 ctgtactttt ttctctactg ttaatagcga ttctaggttg tgttttttta tcactataag
    84301 tagcatattt tccaataaga tttgagtgta ttaatttaac ctttaaaaaa tctctaagtt
    84361 ctatatacac ttcttgttct ttttcaaatt taatttcaag tttattgggg tgtatattta
    84421 catctataca tgatgggtct acttctatat ttaagaagca cactgcatgt ttacctattg
    84481 gaattataga cttataactt tctgttattg catctatgat tattttactt tttacaaatc
    84541 ttttatttat atagatatgt tgtaagtttt tatttgaacg gtatatattg ttattaccta
    84601 tatatccatt cattttaaag tgattgcact taaactctac atctattata ttttccgtta
    84661 tttcttttcc atatatactt ctaatagtgt ttacaagttt tccatcccct ggagtattta
    84721 gcatctgttt attgttattt gtatatttaa attgaatgtt tggattacct attgcaagtt
    84781 tatttatcaa atcacttatg tttatagttt ctgcatgagt agattttaaa aatttctgtc
    84841 ttgctggtgt attaaagaaa atatctttta taatgatggt agttccatta gtagaaccta
    84901 ttggttcttt cgatattatt tttccacctt caacatatat tttagttcct attatttcat
    84961 ctttagtttt agtcgtcatt tctaattttg atacagctga aatagatgcc aatgcttctc
    85021 ctctaaaacc aagagagtat aaatcataca aatcatcaat ttttttaatt ttactagtag
    85081 catgtctcaa aaatgatttt tcaacttcac ttgaaggtat tcctattcca ttatctgtaa
    85141 tcttaattag actttttcct ccatcaatta tatctatgga aattttattt gcacctgcat
    85201 caatggagtt ttcaataagt tcttttacta cagaagaagg tctttctaca acttcacctg
    85261 ctgctatctt atttatagtc aaatcatcta ggatgttaat tatatttttc atttttacac
    85321 ctctaagatt ttatttcttt tgcttttctt tgaagattat aaagagagtt tatagcatct
    85381 aatggagtca tatttaaaat atccagattt aaaatttctt ctgatagtat atctctattt
    85441 acactatcaa aagagatttg agttaaggct acttctttta cagaatcctc ttgattaatt
    85501 ttctctttat catcattttg cttcattaaa gcaacttcat catttaatgc tttaaattta
    85561 gaatttaatt tatcataatc cttttttata tgtttgtagt cttttactat aagttcatgt
    85621 tctattttta gagattcata tttattctta aaattacttt gatttacctt aactaattct
    85681 tcgtccaaat tactattaat tatattattg ttttctttat ctccatttat tgcaacactg
    85741 ttgtaaacat gatttttttc caagtcttta agtatatatt ttgctctttc tatgacttcg
    85801 tctggtaatt tagctaattt agcaacatat attccataac tcttgtctgc tccttgagga
    85861 attatttttc ttaaaaatat tattccttcc ccatcttctt tgactgctat tgaataattt
    85921 ttaacctctt taaactcttc ttctaaatca gtaagttcat gataatgtgt tgcaaataat
    85981 gtcttacatc taatattttt ttgaatatat tccactattg accatgctaa acttatccca
    86041 tcataggtac tagttccacg acctatttca tctaatataa ctaaacttct ctctgttgca
    86101 ttttttaata taagggatac ttcgttcatc tctaccataa aagtagattg accttgagat
    86161 aaatcgtcac tagctccaac tcttgtaaat attctatcta atattggaat atcagcagac
    86221 tctgctggta caaatgagcc tatatgtgcc ataagagcta ttatagcagt ttgtctcata
    86281 tatgttgatt tacctgacat attaggacca gttattatgt taataatgtt ttctccacga
    86341 tttaaataag tatcatttgg aacgaaattt tcctctccta ctatattttc gacaacagga
    86401 tgtctaccat ttcttatatc aagtttatta ttttcattta ttgctggttt tacatagtta
    86461 tttatatgtg caactgttgc aagggacaca aaaacatcta tattagctat agtcttagcc
    86521 actttttgta ttctatctat gtttttatat attgtatctc ttatctctac aaatatctcg
    86581 tattctaaag atttaatctt ttcctctgca tgtagtatct tttcttctat ttcctttaat
    86641 tctggagtta tatatctttc tgcattacta agtgtttgct ttcttatata tgtctcatct
    86701 agctttgctt gtttaaagtt ggcttttgtt atttctatat aatacccaaa aactttatta
    86761 aatcctattt ttaatgattt aactcctgtt ttttctcttt ccctgttttc tatttccttt
    86821 acaagaaagg ctccattctt agaaatctct cttagctcct taagttcatc actaaaatct
    86881 gatttaatta tgtttccatc ttttatggtt atcgtaggtt cttctagaat agcttcatct
    86941 attaaattgt atatatcatc taatttatcc atttctgaaa catactcttt taggattttt
    87001 gcatttgata aatttatagt atcttttaaa ttaggtaact tttctatcga attttttaag
    87061 tgaattaact cttttggtgt cactctctca aatgctatct ttccacatat tctttctata
    87121 tcgtatatat ttttaagtat atcatttagg tcttctctta atataaagtc atcttttatt
    87181 tcttctatta catctaatct attttcaatt ttagatttat ttatcaaagg ttcttctaca
    87241 tattttctta aaagtctacc tcccattgct gtagaagttt tgtcaagtac atgtaataat
    87301 gaaccttttt tcttattccc tcttatagtt tgagtaagtt ctaaattagt tctagtaaac
    87361 atatctagaa ccatatattc tgatgaattg tatatattta tattattaat gttagatgtt
    87421 atttgttttt gagtattgta tatataattc agaagaattg ataagcttga ctttattaga
    87481 cctttatcat caaactttag tttttgtaga taaacatctg gaaaatattc ttttaatata
    87541 tttatatcca aatagttatc actaaaactt tcatttatgt atatattact tacagtagct
    87601 atatctctaa gcttttctat aaagtctaaa tcatttataa ttatttcagt tggatggatt
    87661 tttgcaattt cttcaattac cttatcttca tttaaacatg ttgcattagt ttctcctgta
    87721 cttatatcaa cataagttag acctatatta gtaccatcct tatacaaaga taataaataa
    87781 ttattctttt tattttcaag taaatttcca tctaaaactg taccaggagt gatgaccctt
    87841 ataacctctc ttctaacaat tccttttgct gtagatgggt cttccatttg ttcacctatt
    87901 gctactttat atccattttc aactaatttt gatatatatg aattggctga gtggaaagga
    87961 acaccacaca taggagcacg ttcttctaaa ccacaagctt ttcctgtcaa tgctatttca
    88021 agagcttttg aagctactaa tgcatcttca aaaaacattt cataaaaatc tccaagtcta
    88081 aaaaacagta tacagtcttt atatctattt tttacttcaa gatactgttt catcatagga
    88141 gttaatttat tcatatctat ttgcattatc aaacctcctt cttttctaat taaatattat
    88201 atcatagtag atgattatta ttaacacaat atataaaatt ttgacatata actaaaaaca
    88261 atccaaaatg tatactcaca ttttggattg ctaagtttaa tgcttattaa ataaaaatat
    88321 ttttttttac aataaagata ttatttcttt tttaagttta atgatatttt caaggttatc
    88381 ttcatttaac tttctactat ctataacaaa ttctttcttt actattgatg gtttttttga
    88441 aataacataa attctgtttg atagcattat agcttcgtca atatcatgag ttataagaag
    88501 tattgttgaa tttacttttt tcttaacatc taaaagccat ttttgcatgg atgttttagt
    88561 taatgaatca agtgccccaa aaggctcatc taaaagcatt atgtcattag aatttataaa
    88621 agttctcaag aagttagccc tctgtctcat tcctccagaa agttctgaag gatatttatc
    88681 ttcatatccg cttaatccaa acacctcaaa ataaggtttt accattgacc tagctttact
    88741 ctttttttct ttttttaaaa ttagtggtag tgacacatta tctattatag ttttatatgg
    88801 caagagtaaa tctttttgat acatataact atacttacca tttatattca ctttgccact
    88861 atcataatct gtaagtttag ttataatatt aaaaatagta ctttttccac atccacttgg
    88921 ccctaatata gaaacaaact caccttcata aacatcaata cttatatctt ttaaaacttt
    88981 aatatcttta taagtttttg atacattttc tatagatact tttacttttt tattgtggta
    89041 aaaattcatt tgtgtaagca tcacttgcct tcatatcctt atctattaat ttatattctt
    89101 ttaagaatga tgtatagttg ttccatacac tatctttcat ttctccccat cgtggtgcat
    89161 catctttgta cttgcttgct aaatattctt gactctttaa agctagtttt tcatctactt
    89221 caggtgcatg ttttactaaa atttttgctg attcttctgg attttttatt gcatattcat
    89281 aaccttttgt tgtagctttt aagaattttt tagcaagctc tggattatct ttaagtacag
    89341 tttcattaga aattataagt ggtgtataat aatccaatct ctcatctaaa tcttttactg
    89401 gtataaagtt taagtcatat ccaattaaat cagctttaac tgcatcccaa ccttcaaata
    89461 tccatgcaaa atctacagtt ttcatagctg caaagaaatc atcttgacca gtattaacta
    89521 tctttaactt attaaaatca gctccatttt tcttcataac tgctttaaaa acagcttctt
    89581 ctgatggaga gccccaacca ccataagttt ttccttcaaa atctttagct gttgttatat
    89641 tcttttcttt tggtgatgca aacccagaag tattatgttg tataacagtt gctacagctt
    89701 ttattggaag tggatcttca ctagtctttg cataagtaac ttgttcttga tagcttatac
    89761 caaagtcagc ttttcctgtt gctactaaag tttctgctcc actttcaggt ggttgtacta
    89821 tttcaacatc caaaccttct tctttatagt aacccttatc aagtgctaca aataatccag
    89881 tatgatttgt atttggtgtc caatcaagca ccatagttac ttttttagaa gaagtatctt
    89941 tatcattgtt tttgtcttta ttgttatttg aagaacatcc agttattgtt gccaatgtaa
    90001 aaacacttac taaacctaat attcctaact ttttaaaatt cataattgcc tccctcaaat
    90061 acctttaatc tattaatcta tgtcttataa caactttttt tacagcctgt acaattccta
    90121 caaacattaa actaaatata actactaata tagtagatgc aaatacttta tcaagtgcat
    90181 atgcactttt tgacctaagc atataaacac caagtccttt cgttccacct agccattctg
    90241 caacagttgc tgccattaca gcatacgttg cagatatttt aagtccagaa aaaaatttat
    90301 ccattgccat aggaaattta aggtgaatga atgtattaac tttatttgag tccatagtct
    90361 taaataaatt taaataatct ttatcaatat tctcaatgcc atctacaaaa cttattaata
    90421 taggaaaaaa acaagtaagc attaccatca atacttttgg cattgttcca aatccaaacc
    90481 atatcataaa gagtggtgct ataattattg taggtatcat ctgtgtaacc aacataatag
    90541 gataaagaca tttttttatt attgatacaa aatccatcaa tattccaatt accaatgata
    90601 ttataattgc gactataaaa ccaagtattg cttctcctat agtaaccaca gcatgcatgg
    90661 ataaattttg ataatcttta aaaaacacat taattatatc tactggtgtg ggtagtatat
    90721 actgaggaac ttctaaaact cctaccatag attgccaaag aataagtata aacaaaaatg
    90781 ttgctattgg atatatacta tctttgactt tatctatgat ttctaagttt ttcatctata
    90841 gtcagacctc cagctttttc atctactcta gctactgtta tgactctttc acatccaaga
    90901 ttaaaaggga ttttatgtac cttttttaat aattcaaaaa cttcatcaaa atcaccttca
    90961 acagtagtgc tcattgctcc tatttcacat ttaagaccac ttttttcaat ttcagcaata
    91021 caagcatcta ctactttata catctcttct tcacctttgt aaggtcttag tggcattact
    91081 gctatgtctg cgattaccat ttaaatcact cctttaaaaa taattaatac ctactaggta
    91141 tattttgttt tttattaaaa aattttatta ctaaaaagat attatattta aataaaagaa
    91201 aagtcttatc caaaatagga taagacttat ttttatctta actggtctcc ctacactggc
    91261 attatccaaa caggttcaaa gggtcgagat aaaatctcct ctcagcacat tagctccccg
    91321 aaatatatta tatcttttct acttgattat actacactta tcatatttta acaaattttt
    91381 tatttatatt agatatttta tccgttcaaa aatatctaat ataaattgta cattattaca
    91441 ccaaataaat tatcttaaaa tggtatttta tcaacatctt ccaaaactag attaactgaa
    91501 ttttctagtt tttattttgc tatttcaagc atatttggat gtatatcaat tccatacaaa
    91561 tattgtgcta aatttctgtt ttcactcatc taatttgcaa tcgttacaga ttacagatta
    91621 gaaacagttt ttagactcta cttatcttta tctacaaaaa atctttcaat aaattcatta
    91681 ataatattca gtaatctaaa aataaacctc tatctggatt tttaagatac aaacctttta
    91741 ggaagtatct tttgtgataa tataaaaatt actcgtcatt atcatcaaaa tcctcagcaa
    91801 ccaacatttt atataagaat caaactctat aatataatta ttttatccaa tttatttttg
    91861 agaaataaaa tattttttta atttttaaat tttttaatat gcaccttgaa aaaagaaacg
    91921 ttttcctata ttatggtaat agtagaataa aactaaatag gcaaaactag agaaatttag
    91981 tgacgcaaag ctatagggac taagacttat gaaatgagtt atgtcagcca gttgccaaag
    92041 agatattttc tttttgtttt tatgaatgtt ttttaggggg atatatgata tatgtttatg
    92101 gataaaatgg atagatgtac acatatacta actgcatata tatgcagttc acgcgattac
    92161 tgcaatttta tagatacaca attaaatgat tttatactag aatatggaga gaatgtggta
    92221 gaatcttgtt tgcatcaagt gatggtattg gtaagcagat ataattaaag aaattttatt
    92281 ttctagaaaa ccctttttag ttttatctac gttttataat tcattaaaga actaattaaa
    92341 ataagcttca ttatatattt ttcataaagt aaacagttga gtttatctca tatactgttt
    92401 accccaatta cataattcta ataatataga ttccaatgat ttaccacgtt tagtagacaa
    92461 atattcaact tttggaggaa tagtcggata agaaatcctc ttaataagtc catctatttc
    92521 aagatacttt aattcttgtg acagtatctt atgacttata tgaacaactt ctttttttaa
    92581 ttgactgtaa cgtattggct cttgttttaa aatatgccat aaaataattt ccctccattt
    92641 acttcctatc acagtcatgg taaaaccaac tgaacaatta aaatcttttt gtctttcttc
    92701 aatatttgga aattcttcaa aattattatc tatatccatc tcaatcctct ctttcaaaat
    92761 agtaagtatc taactaaaaa gtgcattctt gtttagcgca ctaattcgta atataatctt
    92821 gattgtagta tagagcctta cataatacta cttttttaga tgtatatgtt taaactttaa
    92881 tatagacata tgttatttta ttaattttat ttaaacagat aataataaat aataatttat
    92941 ctcaagtttt ctatgtagat aaactaatct aatgtttaga aaggattata taatatgaat
    93001 aaaaaatttc gtctttatca agttgactca ttacaaaaga aaaatttaca ggtaatccag
    93061 ctggtgtaat tacaaatgct gatggcttat ctgaatcaca aatgcaaaaa atagcaagag
    93121 aattaaataa ttcagaaact gcttttattt tcaataactt ggctaaaaat catcaagaaa
    93181 attatgatgt acatatcaga ttttttacac caactaatga ggttcctata tgtggtcatg
    93241 ctactattgc tgcccattat gttagagcag tagaaaacca attcaataac aaaacagtat
    93301 ttcaaaaaac tggtgctgga atattaccag ttgatattat aaaaaaagat aatgattatg
    93361 aaataattat gacacaagga aaaattgaag tatctccacc attacaacaa acctatcaaa
    93421 aaagattact taatgcattt ggtattttaa aggaagatat tcgtacagat tgtcctattg
    93481 ccatatcatc tacaggacat tcaaaagtta tgattggaat aaaggaatta tcaacattaa
    93541 atagtttatc tccaaattta tatgaattat cgaaaataag tcaagaaata aaatgtaatg
    93601 gatattatat ttttacatta cataataaag aaactctaca agttcatgga agaatgtttg
    93661 ctcctgcaat tggtatttca gaagaccctg ttacaggaaa tgctaatgga cccttaggtg
    93721 cgtaccttgt acattataaa gtaataccta cacccaacac agagtttata tttgaagcag
    93781 ttcaaggaga agcaataaaa cgcaaaggca agatgttagt aagagtaatt attttagata
    93841 ataagccagt tgaagtaaaa ataattggaa aagctgtaat tgcattctca acaaacatag
    93901 aaatctaatt atagattcct tctaagtaaa tttttgaact ttttaatact aatttaataa
    93961 caaactaatt tatatacaat caaattaatt tttttattat
//
LOCUS       DAEQAF010000004        84452 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.004, whole genome shotgun sequence.
ACCESSION   DAEQAF010000004 DAEQAF010000000
VERSION     DAEQAF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 84452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84452
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.004"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(72..845)
                     /locus_tag="KRN00_000357"
     CDS             complement(72..845)
                     /locus_tag="KRN00_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBH1826250.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(845..1231)
                     /locus_tag="KRN00_000358"
     CDS             complement(845..1231)
                     /locus_tag="KRN00_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1826251.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1256..1573)
                     /locus_tag="KRN00_000359"
     CDS             complement(1256..1573)
                     /locus_tag="KRN00_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBH1826252.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1585..1845)
                     /locus_tag="KRN00_000360"
     CDS             complement(1585..1845)
                     /locus_tag="KRN00_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBH1826253.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1845..2141)
                     /locus_tag="KRN00_000361"
     CDS             complement(1845..2141)
                     /locus_tag="KRN00_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBH1826254.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="KRN00_000362"
     CDS             complement(2210..4636)
                     /gene="gyrA"
                     /locus_tag="KRN00_000362"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBH1826255.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="KRN00_000363"
     CDS             complement(4656..6557)
                     /gene="gyrB"
                     /locus_tag="KRN00_000363"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBH1826256.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6558..7673)
                     /gene="recF"
                     /locus_tag="KRN00_000364"
     CDS             complement(6558..7673)
                     /gene="recF"
                     /locus_tag="KRN00_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBH1826257.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSANRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="KRN00_000365"
     CDS             complement(7691..7897)
                     /gene="yaaA"
                     /locus_tag="KRN00_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBH1826258.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDKI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8034..9140)
                     /locus_tag="KRN00_000366"
     CDS             complement(8034..9140)
                     /locus_tag="KRN00_000366"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBH1826259.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="KRN00_000367"
     CDS             complement(9382..10704)
                     /gene="dnaA"
                     /locus_tag="KRN00_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBH1826260.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11360..11497
                     /gene="rpmH"
                     /locus_tag="KRN00_000368"
     CDS             11360..11497
                     /gene="rpmH"
                     /locus_tag="KRN00_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBH1826261.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11575..11919
                     /gene="rnpA"
                     /locus_tag="KRN00_000369"
     CDS             11575..11919
                     /gene="rnpA"
                     /locus_tag="KRN00_000369"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBH1826262.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            11951..12202
                     /gene="yidD"
                     /locus_tag="KRN00_000370"
     CDS             11951..12202
                     /gene="yidD"
                     /locus_tag="KRN00_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBH1826263.1"
                     /translation="MNKIIYILKEISKHLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12234..12941
                     /locus_tag="KRN00_000371"
     CDS             12234..12941
                     /locus_tag="KRN00_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH1826264.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12910..13539
                     /locus_tag="KRN00_000372"
     CDS             12910..13539
                     /locus_tag="KRN00_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBH1826265.1"
                     /translation="MRKSLKLIKSKSKEEAISKAIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13651..15030
                     /gene="mnmE"
                     /locus_tag="KRN00_000373"
     CDS             13651..15030
                     /gene="mnmE"
                     /locus_tag="KRN00_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBH1826266.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENVIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15128..17020
                     /gene="mnmG"
                     /locus_tag="KRN00_000374"
     CDS             15128..17020
                     /gene="mnmG"
                     /locus_tag="KRN00_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012065747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBH1826267.1"
                     /translation="MKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSIA
                     LMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQADK
                     FKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVYL
                     NSKIYMGEVAFYEGPNALGYAKYLTDSLVELGLRMRRFKTGTPARVHRDSIDFSVMSL
                     QEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPRY
                     CPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLENC
                     KIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINAV
                     RKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLTQ
                     KGYDIGLVKKDRYERFLNKKAAVEKEFERLKNERVTPKEVNSLLEEKGATPIKVGISL
                     YEFLKRPEVTYELLEELGKGAGEDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLEN
                     KKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRRT
                     RGGKGE"
     gene            17013..17732
                     /gene="rsmG"
                     /locus_tag="KRN00_000375"
     CDS             17013..17732
                     /gene="rsmG"
                     /locus_tag="KRN00_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBH1826268.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVEWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17895..18680
                     /gene="noc"
                     /locus_tag="KRN00_000376"
     CDS             17895..18680
                     /gene="noc"
                     /locus_tag="KRN00_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBH1826269.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18815..19588
                     /locus_tag="KRN00_000377"
     CDS             18815..19588
                     /locus_tag="KRN00_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBH1826270.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19590..20453
                     /locus_tag="KRN00_000378"
     CDS             19590..20453
                     /locus_tag="KRN00_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBH1826271.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20486..21628
                     /locus_tag="KRN00_000379"
     CDS             20486..21628
                     /locus_tag="KRN00_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1826272.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(21761..22336)
                     /locus_tag="KRN00_000380"
     CDS             complement(21761..22336)
                     /locus_tag="KRN00_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBH1826273.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKNNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
     gene            22596..23888
                     /locus_tag="KRN00_000381"
     CDS             22596..23888
                     /locus_tag="KRN00_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1826274.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
     gene            23993..24595
                     /gene="yedF"
                     /locus_tag="KRN00_000382"
     CDS             23993..24595
                     /gene="yedF"
                     /locus_tag="KRN00_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBH1826275.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            24668..24931
                     /locus_tag="KRN00_000383"
     CDS             24668..24931
                     /locus_tag="KRN00_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBH1826276.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            24946..25131
                     /locus_tag="KRN00_000384"
     CDS             24946..25131
                     /locus_tag="KRN00_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBH1826277.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            25234..26430
                     /locus_tag="KRN00_000385"
     CDS             25234..26430
                     /locus_tag="KRN00_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1826278.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            26644..26922
                     /locus_tag="KRN00_000386"
     CDS             26644..26922
                     /locus_tag="KRN00_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBH1826279.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            26959..27393
                     /gene="ssb"
                     /locus_tag="KRN00_000387"
     CDS             26959..27393
                     /gene="ssb"
                     /locus_tag="KRN00_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1826280.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            27412..27639
                     /locus_tag="KRN00_000388"
     CDS             27412..27639
                     /locus_tag="KRN00_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBH1826281.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            27782..28102
                     /locus_tag="KRN00_000389"
     CDS             27782..28102
                     /locus_tag="KRN00_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH1826282.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            28110..29066
                     /locus_tag="KRN00_000390"
     CDS             28110..29066
                     /locus_tag="KRN00_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBH1826283.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            29077..31071
                     /locus_tag="KRN00_000391"
     CDS             29077..31071
                     /locus_tag="KRN00_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBH1826284.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            31072..31521
                     /locus_tag="KRN00_000392"
     CDS             31072..31521
                     /locus_tag="KRN00_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBH1826285.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            31540..32868
                     /gene="dnaB"
                     /locus_tag="KRN00_000393"
     CDS             31540..32868
                     /gene="dnaB"
                     /locus_tag="KRN00_000393"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBH1826286.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            33073..33381
                     /locus_tag="KRN00_000394"
     CDS             33073..33381
                     /locus_tag="KRN00_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826287.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            33463..34752
                     /locus_tag="KRN00_000395"
     CDS             33463..34752
                     /locus_tag="KRN00_000395"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBH1826288.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYSARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            35078..35153
                     /locus_tag="KRN00_000396"
     tRNA            35078..35153
                     /locus_tag="KRN00_000396"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35111..35113,aa:Lys,seq:ttt)
     gene            35160..35234
                     /locus_tag="KRN00_000397"
     tRNA            35160..35234
                     /locus_tag="KRN00_000397"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35193..35195,aa:Glu,seq:ttc)
     gene            35239..35314
                     /locus_tag="KRN00_000398"
     tRNA            35239..35314
                     /locus_tag="KRN00_000398"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35272..35274,aa:Val,seq:tac)
     gene            35348..35422
                     /locus_tag="KRN00_000399"
     tRNA            35348..35422
                     /locus_tag="KRN00_000399"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35380..35382,aa:Thr,seq:tgt)
     gene            complement(35804..36796)
                     /locus_tag="KRN00_000400"
     CDS             complement(35804..36796)
                     /locus_tag="KRN00_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1826289.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(36805..37863)
                     /locus_tag="KRN00_000401"
     CDS             complement(36805..37863)
                     /locus_tag="KRN00_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH1826290.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            37988..39451
                     /locus_tag="KRN00_000402"
     CDS             37988..39451
                     /locus_tag="KRN00_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBH1826291.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIKKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIYDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            39553..40350
                     /locus_tag="KRN00_000403"
     CDS             39553..40350
                     /locus_tag="KRN00_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1826292.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            40363..42465
                     /locus_tag="KRN00_000404"
     CDS             40363..42465
                     /locus_tag="KRN00_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBH1826293.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            42533..43012
                     /gene="rlmH"
                     /locus_tag="KRN00_000405"
     CDS             42533..43012
                     /gene="rlmH"
                     /locus_tag="KRN00_000405"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBH1826294.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLPVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            43901..45163
                     /gene="tetA(P)"
                     /locus_tag="KRN00_000406"
     CDS             43901..45163
                     /gene="tetA(P)"
                     /locus_tag="KRN00_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter TetA(P)"
                     /protein_id="HBH1826295.1"
                     /translation="MVNKLSAYKTYLLFSAITAMCFSLVATVMIVYHIETVHLNPLQL
                     ILVGTTLEVACFIFEIPTGIVADVYSRKLSIVIGVVLTGVGFILEGSISSFVFVLVAQ
                     IVWGLGSTFISGSVEAWIAEEEKDKDLDKIYIKGAQAGQIGSVIGIVLSTVIANLSVR
                     LPIIVSGVLFIILALFLWLYMPENNFKSSAPEDLNTFKKMGYTFKSGLKFIKNKPIII
                     ILLSVTLFYGLSSEGYDRLSNMHFLQDTMLPKLGNLKPVTWFGIFGIAGMILSAIVMH
                     FMEKKLKDDDKNKNGKLLLCINIFYISFMFIFAITKRFNLMLIAYLATSTFRTINEPI
                     FSAWLNGHIDDKARSTVLSINGQINSLGQILGGPIIGIIATNISVSMGIACTSLLVTP
                     VLVLYIVAMIMDKKVVDRVGGIDYEENN"
     gene            45147..47105
                     /gene="tetB(P)"
                     /locus_tag="KRN00_000407"
     CDS             45147..47105
                     /gene="tetB(P)"
                     /locus_tag="KRN00_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012478245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein TetB(P)"
                     /protein_id="HBH1826296.1"
                     /translation="MKKIINIGIVAHVDAGKTTITENLLYYSGAIKSVGRVDLGNTQT
                     DSMELERKRGITIKSSTISFNWNNVKVNIVDTPGHVDFISEVERSLSVLDGAILVISG
                     VEGIQSQTRILFETLKELNIPTIIFVNKLDRIGANFNKVFEDIKKNMSNKVVRLQEVY
                     DVGSKAVYIKKLFDTCMINDDAIDVLSDLDEAFLERYIGGIEPDKEEIQEKLSLYASE
                     GSLYPVFCGAAAIGLGVEDLLDGICSYFPFAGDDCESDLSGVVFKIERTSKNEKKVYV
                     RLFGGKISVRDKIQVPNKEIAEKVKKINRLENGGVVEAQRIEAGDIGILYGLTSFQVG
                     DVIGISNDKIKNISIAKPALKTTISAIDKEKNPELFKALTLLAEEDPLLELEMNDIDK
                     EIYVNLFGEVQMEILSSMLDDLYGIKVEFSNIETIYKETPKGFGASIMHMQEDLNPFW
                     ATVGLEIEPAGRGEGLRYISNVSVGSLPKSFQNAIEEAVIKTSKQGLFGWEVTDVKVT
                     LSCGEFFSPASTPADFRNVTPMVFMEALYKAQTVLLEPLHEFELKIPQNALSKAVWDL
                     ETMRATFDNPIVIGDEFSIKGLIPVENSKEYKMKIASYTEGRGMFVTKFYGYKEASAE
                     FSKARKKTTYDPLNKKEYLLHKLNAIRD"
     gene            47297..47575
                     /locus_tag="KRN00_000408"
     CDS             47297..47575
                     /locus_tag="KRN00_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826297.1"
                     /translation="MKIDFKITKDDYISFNLHHLENSKSQKSTFNILRYAVPIILSIP
                     IYFTGTGIFNQPSIYWIIVAIVFLVIWILTYPKQYKKLVAKETDKLIS"
     gene            48012..49193
                     /locus_tag="KRN00_000409"
     CDS             48012..49193
                     /locus_tag="KRN00_000409"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826298.1"
                     /translation="MGERKVNLDVSNEIYLRMIKEGYSPEDIKEMVIEEFNQFFMNNQ
                     VLERNAIDVLLPELINLTKLKQYGKYYREFTMCLDMYKNSMNIDKEECFKAFANWSSD
                     INKAINKYWIIYNLDKVREKLTIEEYVEVTFKKIGKLIEGIIKPYSFNILNNIYIIKG
                     KKEKVNTFERKDLGTFFEEIIQSNITGELFRIQLDTISGIKEIKLNQLRNIVAHENYE
                     IEGEIINCFIKNKNEIKDSFRISIEQLKKCFGDVYYTLGAIKLAYTIFFVDNIDEIIK
                     YNPDKSIIRVEQLITNTFLGIQSQGFKIIDFVEDSIESKLILKDALCDNEKQRMIHSS
                     QFLFRLWEITKAKNNVIEYLDNTGKLKAIFQLDSNVCERINNGELEPLAQAEMMKIKI
                     I"
     gene            49333..50064
                     /locus_tag="KRN00_000410"
     CDS             49333..50064
                     /locus_tag="KRN00_000410"
                     /inference="COORDINATES: protein motif:HMM:NF024800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1826299.1"
                     /translation="MKCPVCGASMTVSRSTRKIKDGTEAVNEYYACGNWTNKGTAVCN
                     SNSVKAEVADEVVINNLIEKVNNEILLKRIIDNINKNKSSKLKPKLDETNLVNKEIDK
                     LNGKKNSNIELFEDGILTKSELAERVKKLNEEIDTLKFRLDEIKQDVMLAEGEPAPFE
                     LVSQVMKQFGQVFKESSTRQQRKQLLNLLVSKITIDKLRAIDTIELQINEDIISYLFK
                     EGSFKEDPSFFSTFIINCSCFKFTI"
     gene            50280..50591
                     /locus_tag="KRN00_000411"
     CDS             50280..50591
                     /locus_tag="KRN00_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1826300.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            50639..50956
                     /locus_tag="KRN00_000412"
     CDS             50639..50956
                     /locus_tag="KRN00_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1826301.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            51169..51870
                     /locus_tag="KRN00_000413"
     CDS             51169..51870
                     /locus_tag="KRN00_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1826302.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            52094..53395
                     /locus_tag="KRN00_000414"
     CDS             52094..53395
                     /locus_tag="KRN00_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1826303.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            53532..54626
                     /locus_tag="KRN00_000415"
     CDS             53532..54626
                     /locus_tag="KRN00_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH1826304.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            54628..55761
                     /locus_tag="KRN00_000416"
     CDS             54628..55761
                     /locus_tag="KRN00_000416"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBH1826305.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            55779..56888
                     /locus_tag="KRN00_000417"
     CDS             55779..56888
                     /locus_tag="KRN00_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBH1826306.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            56953..57693
                     /locus_tag="KRN00_000418"
     CDS             56953..57693
                     /locus_tag="KRN00_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBH1826307.1"
                     /translation="MNCIPQYYKNRVCLNVLAESIKNAKEVYDACDGHVLIGVLSKNY
                     STVEVAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            57698..58690
                     /locus_tag="KRN00_000419"
     CDS             57698..58690
                     /locus_tag="KRN00_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBH1826308.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGVGDGYVV
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(58878..59759)
                     /locus_tag="KRN00_000420"
     CDS             complement(58878..59759)
                     /locus_tag="KRN00_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1826309.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            60032..61420
                     /locus_tag="KRN00_000421"
     CDS             60032..61420
                     /locus_tag="KRN00_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826310.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            61448..62401
                     /locus_tag="KRN00_000422"
     CDS             61448..62401
                     /locus_tag="KRN00_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1826311.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            62461..62685
                     /locus_tag="KRN00_000423"
     CDS             62461..62685
                     /locus_tag="KRN00_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826312.1"
                     /translation="MNEKPSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIGQAREATNYNIGNG"
     gene            62678..63190
                     /locus_tag="KRN00_000424"
     CDS             62678..63190
                     /locus_tag="KRN00_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH1826313.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            63222..64076
                     /locus_tag="KRN00_000425"
     CDS             63222..64076
                     /locus_tag="KRN00_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBH1826314.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            64610..65404
                     /locus_tag="KRN00_000426"
     CDS             64610..65404
                     /locus_tag="KRN00_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1826315.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            65508..66314
                     /locus_tag="KRN00_000427"
     CDS             65508..66314
                     /locus_tag="KRN00_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1826316.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            66376..66897
                     /locus_tag="KRN00_000428"
     CDS             66376..66897
                     /locus_tag="KRN00_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1826317.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            67312..69399
                     /locus_tag="KRN00_000429"
     CDS             67312..69399
                     /locus_tag="KRN00_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1826318.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            69414..69701
                     /locus_tag="KRN00_000430"
     CDS             69414..69701
                     /locus_tag="KRN00_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1826319.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            69728..70999
                     /locus_tag="KRN00_000431"
     CDS             69728..70999
                     /locus_tag="KRN00_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBH1826320.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            71057..71656
                     /locus_tag="KRN00_000432"
     CDS             71057..71656
                     /locus_tag="KRN00_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1826321.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKILKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            71661..72566
                     /gene="dapA"
                     /locus_tag="KRN00_000433"
     CDS             71661..72566
                     /gene="dapA"
                     /locus_tag="KRN00_000433"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1826322.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            72672..73304
                     /locus_tag="KRN00_000434"
     CDS             72672..73304
                     /locus_tag="KRN00_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBH1826323.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNANKIREIIKNIRKI"
     gene            73782..76289
                     /locus_tag="KRN00_000435"
     CDS             73782..76289
                     /locus_tag="KRN00_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1826324.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAECPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNRNYQDYEDYEKFFEDES
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSMI"
     gene            76631..78793
                     /locus_tag="KRN00_000436"
     CDS             76631..78793
                     /locus_tag="KRN00_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBH1826325.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            78798..79415
                     /locus_tag="KRN00_000437"
     CDS             78798..79415
                     /locus_tag="KRN00_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826326.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            79604..79948
                     /locus_tag="KRN00_000438"
     CDS             79604..79948
                     /locus_tag="KRN00_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBH1826327.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            80518..81384
                     /locus_tag="KRN00_000439"
     CDS             80518..81384
                     /locus_tag="KRN00_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1826328.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            81497..81901
                     /locus_tag="KRN00_000440"
     CDS             81497..81901
                     /locus_tag="KRN00_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBH1826329.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINVGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            82065..82514
                     /locus_tag="KRN00_000441"
     CDS             82065..82514
                     /locus_tag="KRN00_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1826330.1"
                     /translation="MKSGIILEMKQINSIEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(82670..83047)
                     /locus_tag="KRN00_000442"
     CDS             complement(82670..83047)
                     /locus_tag="KRN00_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1826331.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            83309..84226
                     /locus_tag="KRN00_000443"
     CDS             83309..84226
                     /locus_tag="KRN00_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBH1826332.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT        32413 a         9854 c        14190 g        27995 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata ccatctttaa aacagtaggt caatactttt
       61 tttatatttt tttataaatt tttttcatat tcttttttca gcttctctac tacctttttc
      121 tctagtctag aaacagtcat ctgtgatatc cctagttctt tagctatact agattgtgtt
      181 ttatcaaaga aaaatctatc tttaaaaatt ttaacttcta attcatttaa agtttcaata
      241 aacttattaa taaaatcttc atactctata cttccaaagt taccttcttc ttttccaatc
      301 ttatcaataa gagttatatc tttatcctct gaatcatcat tacttgatga atccaaagac
      361 attggttgat atccataaga agcctccata gcctctaaaa catcttcttc actaacgcct
      421 atataatcag ctatatcttt tacctttgga tgcttcttat tttcttgttc taatttaatc
      481 ttcgcatcac ttatcttttt gcttaattcc tgtattcttc ttgggactct aagtgtccat
      541 accttatctc taaaatactt ttttatttct cctactatag ttggtgttgc aaagctggag
      601 aactcaaatc ctttctcaac atcatatcta tcaatagcat aaattaatgc caatgaagca
      661 acttgatata tatcttcaaa atcaacacct ttgtttatat acttcttagc taacaatctt
      721 gctaaataca gatgtctttc aataagaata tttctaatgt ctacattttt atttttatta
      781 tataaattaa atagctcttt tgtatccata tttaggtaat gtgtagcatt agctacattt
      841 ttcattaaat atcaactcct aaatatttag tcatttttat ttttgtccct tgattatgtt
      901 ctgattcaat atctacatca tccattaaag ttttaattat aaacaatcca agaccactct
      961 cttttggatt ctctaaatct ggtgtactta ttgagctaac atcatatcct tttccattat
     1021 cttgaatttc tatattaatt gcattatcta aaatattaaa tactatatta aacacatcat
     1081 ctttactgtg ttttattgca tttgtacatg cttcagatac tgctaccttt atatcttcta
     1141 tatcatctat tggaaaaccc atcttattgg caattccaga tgctgttaat cttattatac
     1201 taacataatc tggatttgta gtaatttcca tctttatagt ctcacaagcc aaagtttatc
     1261 cctccacttt aaatatttta tctagacctg ttatagtaaa aatctttctt acgttactct
     1321 taggatttac tatgtatatc tctttttcat ttatttttaa tttttttaat acacctatca
     1381 tagctcctaa gcctgttgag tctatataat ctaaatcttt aagattaatc tttacatcta
     1441 acatattttt ttctattaaa gcatgtaaat gttcctttag tttatctgct gtagaaacat
     1501 caagttctcc atcaagacaa acattccaaa atttattttg tgaatctaaa tttgaatcaa
     1561 tattcataga catgtaaaaa cctcctattt ccttttaata attttaaata tatttcctat
     1621 actcaatatt ttattaatta cataaactat atcatctatt ccctttgata ttgatgatgc
     1681 attttcaaca atatcttgta tatgtctttc attataatct acaatcttat atgccttttc
     1741 aacaacctta tttatgctgt ttagagtttt agctaaataa attgctacta taagagcaga
     1801 gcttcctact aacactgctc caatttgcca cccccatgca ttcattagtt aacatctccc
     1861 tcatcatcaa agcttttact tattactata tcttcttctg aaatctttat atcttcttca
     1921 ttattatcat catccactaa atttattatt ctctctttaa catcattaaa tgtttcatgt
     1981 agaacttctt ttggattttc tttgacatca ttaaacttct cttttgtttc ttttcttagt
     2041 tcagaacctt ttttaggtgc aaaaaacata ccaaatataa accctaaaat agctcctaat
     2101 aataaaaatc cacctttttt acaacttctt ttattgcaca taacaattac tcctttcaat
     2161 tttaaatttt tatctaacta cattatacaa aaagaatagg atatttatcc tattcttctt
     2221 caatatttat tttggcaatc gaaactacat tgacttcatc attcgtcttc attaatttaa
     2281 caccacttgt aactcttcca aacagtgata tttcattgac tcttattcta ataagaactc
     2341 catcagaatt tataatcatt atctcatcat cttcgttgac catatctgca cctacaattg
     2401 taccagtttt ttcagatata ttataagttt taattccttt accagctctt atttgacttc
     2461 tatactcttc tatatttgtt ctctttccaa aaccattctt acttacaact aacacatctg
     2521 tacctttact gcaaaggttc atagacacaa caaaatcttc tttacttaaa gttatacctt
     2581 ttacacccat tgctgttcta cccatatatc ttatatcatt ttcatcaaat cttatagaca
     2641 taccttcttt agttactaaa agtacttctt gttttccatc tgtaagttct actccaataa
     2701 gctcatcatc atctcttaaa cctatagcaa taagaccaga tttatttata tttttgaact
     2761 cttctctctt agtcttttta acaatacctt ttttcgttgc aagtaataaa tattcatttt
     2821 catcattacc atcaataggt attagagtag caattttctc atctgctgac aattgaagta
     2881 aattcactat agcagtacct ttagcctgtc tcttaccttc tggtatttca tatgcattta
     2941 atttaaatac tctaccttta tttgtaaaga ataatagtct actatgagta gttgtagtta
     3001 ccaagtgcct tacaaaatct tcttctctag ttgtaagtgc tgaaatacct cttccacccc
     3061 ttttttgact cttataagta tcagatggaa gcctttttat atatccaaag tgagtaagag
     3121 ttattgctat ttcttcatca cttataagat ctctcatatc tatttcgcct tcagcatgtc
     3181 ttatttctgt tcttctctca tcagagtaat tttcttttat tattgtaatt tcatccttta
     3241 ttacatttaa aagtaatctt tcatcagcta aaatctcttt taatctattt atcttcttga
     3301 ttaaatcttc atattcagct tctatcttat ctctttctaa acctgtaagt ctttgaagtc
     3361 tcatatctaa tatagcttgt gcttggattt cagttaattt gaatttttct attaaaccta
     3421 gcttagcttc ttgcccagtc tttgaagctc ttatcaagct tataacagca tctatattat
     3481 ctaaagcaat ctttaatcct tctaaaatat gtgctcttgc ttcagcttta tttagttcaa
     3541 atttagttct tcttgtaaca acatcttctt gatgtttaat ataatgatat aatatttgtt
     3601 taagatttaa aactcttggc tgaccatcta caagtgcaag cattattata ctaaaagtat
     3661 cttccatttg agaatgttta tacaaattat ttaatactat attagcatta gcatccctct
     3721 ttaattctat aacaattctc ataccatttc tattactttc gtctcttagg tctgatatac
     3781 cttctattct cttttcttta actaactctg ctattctttc aacgagttta gccttattta
     3841 cttgataagg tatttctgta actattattt gctgttttcc ttttggtagc tcttctataa
     3901 aagctctaga cctaacttta acttttcctc ttccagttct gtatgcttct gctatacttt
     3961 cttttcccat tataattgca gctgtaggga aatctggtcc ttgaacaaat tttattaaat
     4021 catctacact acactctgga ttatctatca aatatacagt tgcatcaatt acttctgcta
     4081 aattatgtgg aggtattgaa gttgccatac caacagctat accatttgag ccatttacta
     4141 ataaattagg atatctagct ggcaatactg aaggctcttt taacgactca tcaaagtttg
     4201 gtttaaagtc tacagtttcc ttttcaatat ctctcagtag ttctaatgat aatttactca
     4261 ttttagcttc tgtataacgc atagcagctg gtgaatcccc atcaacagaa ccaaagttac
     4321 catgaccatc tactaaaagt gctctagttg aaaaatcttg tgccattctt accatagcat
     4381 aataaacagc agtatctcca tgaggatggt acttacctaa aacgtcccca acaatacgag
     4441 ctgacttcct gtatggttta tctggagtta aatttaactc actcattgaa tataatattc
     4501 ttctatgaac tggctttaaa ccatctctaa catcaggaag agcacgtcca gctataacac
     4561 tcattgaata atcaatatac gattttttca tttcttccgc tatttcaata gggagtattt
     4621 tgttattttc ttccatgtat actaatcccc tctctctata tatctaagtt tctaacaaat
     4681 cttgcatttt cttctataaa ttcttttctt ggagcaacct tatcacccat aagcattgaa
     4741 aatacttcat ctgcaattgc agcatcttct acagtaactt gtaataaagt tcttgtctca
     4801 ggattcatag ttgtttccca taattgctct gcattcatct ctccaagacc tttgtacctt
     4861 tgaagttcaa caccatttct tccaatttca tctagtaaga tatttaactc tttatctgag
     4921 taaacataat gttccttctt ttgctttgtc actttatata aaggtggctg tgctgcataa
     4981 acatacccct catctataag aggtctcata tatctaaaga agaatgttaa taataaagtt
     5041 cttatatggg ctccgtctac atcagcatcg gtcataatta taattttatg atacctagcc
     5101 ttatctatat caaaatcttc tccaatacca caaccataag ctgttatcat attttttatt
     5161 tcatctgaag atagtatcct atctagtctt gatttctcaa cattaagtat tttccctctt
     5221 aatggaagta tagcttgact atttctatct ctaccttgtt tagctgaacc tcctgctgaa
     5281 tccccttcga ctaagaatat ttcactttta gatggatctt tttctgcaca atctgcaagt
     5341 tttccaggta aagatgtact ttctaataca ctttttctcc ttgttaattc tcttgctttt
     5401 tttgcagctt ctctagctct ttgtgctctt aaagctttat caactatgat tcttgctgtt
     5461 gatgggtttt cttctaggaa agaccccagt tcatcaactg ttacactatc aactatacct
     5521 ctcataaagc tattacctag ctttgtttta gtttgacctt caaattgagg ttctggtaat
     5581 ttaactgata ctactgctgt aagaccttct cttatgtctt caccaagtag gttaacatca
     5641 ttttccttta aaaatttatt tctcttagca taatcattta cagttttagt aagagctgct
     5701 ttaaatccac ttaaatgaga accaccttca tgtgtattta tattgtttgc aaaagaatat
     5761 atgttctctg tataaccatc tgtatattgc atagctagtt caacaaaaca atcatcaacc
     5821 tttttatcta tataaactat gtcatcatgt ataccagttc tagatttatt taaatactta
     5881 atatattcta ccaaaccacc tgtatagtga aattcttttc ttttttcttg tccttctctt
     5941 ttatcttcaa atactatttt tattccttta ttcaagaaag aaagttctct aagcctatac
     6001 tccaatgttt catatttaaa ctctatttca tcaaatattg tctcatctgg cataaattga
     6061 atcattgttc ctttatcttg agattctcca actacttcaa gcttagatgt tggcaatcct
     6121 ttctcatatg tctgcttata tatctttccg tttaaataaa cctctgctac catccatttt
     6181 gacaatgcat taactacaga aacaccaact ccatgaagac ctccagatac tttatatcct
     6241 ccgcctccaa actttcctcc tgcatgaaga ttagttaata ctgtttctaa agttgattta
     6301 ccagttttag gatgtatttc aacaggtata cctcttccgt tatcttttac taaaacactg
     6361 ccatcttcat taatagatac atatatgtct gaacaatatc cttgtaaagc ctcatctata
     6421 ctattatcta caacttcata aactaagtga tgtaaacctc tagggcttgt actaccaata
     6481 tacatacctg gtctttttct aacggcttct aatccctcta atacttgtat ctgacttgca
     6541 ccgtattctt gtttcattta atttcctcca ttctctatgc taataacatc gccattttca
     6601 atattaaata ttgtaacatt tttttcatca aatatttttt tatgtgaaac ttcagcactt
     6661 gttataaaca tttgaacatt gcttaaatta tttactaaaa gtttttgtct tgcttcatct
     6721 aactcactaa aaacatcatc taaaattaat actggatatt cttcaacttc attttttatt
     6781 aattctatct ctgataactt taatgatatt gaagcagttc tttgttgacc ttgtgaacca
     6841 aaaagtcttg catctaaatc atttatgaat atatttaagt catctttgtg tataccatat
     6901 ctggtagtct tagattctat atcattaggt ctattcgctg acaacttggc taaaaattta
     6961 ttatatactg tatctatagt atcttcatca gttatattta tttgattttt atatcgaatt
     7021 gataatcttt caactccatt agtcaaattc atatgcatat tttcagatat attagctatc
     7081 ttttttataa agtctctacg caaaatataa atataacttc catactttgc taacgtatca
     7141 tcatatacat ctaataaagc ttcatcaaca tgtatatttt taagcaccct actcctttga
     7201 gaaagtgttt tattataatt ggtaagatat ttataatatt taggtataat ctgactaatc
     7261 tctttgtcta taaatgccct tctttcttta ggaccctctt taaccaacct taaatcctca
     7321 ggagaaaata taacaacatt taagttgcca agtagctctt gtatcttttg taaaggaact
     7381 ttatttattc ttatcccttt tttatctttt ccaataatta gctctattag actatattta
     7441 ttatattttg aaaaacttcc tccaatatat aagttttcac tattaaatct aaccatttct
     7501 ttatctttgt tagtcctaaa tgattttcca aaagaaagca tataaataga ttctactata
     7561 tttgtctttc cttgaccatt tttaccaaca agtagattta ctttcccatt aaattccaga
     7621 tgcaactttt tataatttct aaaattaaca agttgcaaac ttttaagttt cacaaaaagt
     7681 tctccttttt ttacaatact tttattttag ttccttctat ttcaactata tctcctgatt
     7741 ttatcttttt tcctcttctt aattctattt tatcatttac tgtcactaaa ccttcttgaa
     7801 ttaaaaattt tgcatgacct cctgttgatg caatctctgc taatttaaga aattgatcca
     7861 actttatata ttctgattct atagttattt cagtcataat agttcctcct tgtcactatt
     7921 ttaaacaaat tcctattgat acactaaaag tatattatac cataaatatg cttataaaag
     7981 gagttgtcta agattagaaa aattttctac aaaagacaac tccttcatgt ctgctatata
     8041 tttgatgata ttcttactgg aagcagtaag taaatataat taacatcatc tgttggttta
     8101 attatacaag gatttacatt tgtagtaaat tctataaata tttcctcatt atctatattt
     8161 ttcaaacctt cgataaaata tctagaattg aaagctatat ctaggtaatc tccatctaaa
     8221 tctatttcaa cttcttcata cacatttcct ttttctgtat tagaagtaat tgccattact
     8281 ttatctctta tagataactt tataagatta tttttttctg attgagacaa taaagacgct
     8341 ctctctatac tatttaaaag ttccttagta tttaatttaa ctctgctgtt atgttctctt
     8401 ggcaataatt ttttataatc aataaaatct ccttcaagca atcttgtaat aattttcgta
     8461 tcattaatta taaaaatagc atttttttcg ttaaatccaa ctttaacatt atcctctcca
     8521 gaaagcaaac tatttacatc tataagtgtc tttccaggaa ttatgacttt tatattttca
     8581 gttaaactat caaccgaaca actttttaca gctaatctat atccatcaat tgctactaaa
     8641 tttaagtttc tatctacaat ttctaaaagt tctcccatta aaacaggttt tgtttggtcc
     8701 tgtgagatag caaatacagt ttgtttaatc atatttttta ggatttcttg aggtatgcta
     8761 tataaatctt cttcatttaa ttctggtaat ttaggaaatt cttttgctgc ataaccttta
     8821 attttaaatc ttgaatttac acaatttatg taaatattat tttctgaatc agtttctatc
     8881 tcaacaaagg aatctggtaa ttttctaatt atatctccaa atagccttgc atctacaaca
     8941 acatcacctt tttctatgat ttctgcttgt acataagttt ctattcctat ttcagcatca
     9001 tatccagtaa gttttaattg accttcttct gtagatataa gtataccttt taataattct
     9061 atagttgttt ttccattaat agctttttga gcaattccaa ttctatttgc taggattttt
     9121 tgattacaaa ttattttcaa tgtggataac ctcctctggc tttttatata taaaaataag
     9181 ttaaaatcat agtagtaata gtagtaggtg ttgttgataa tgttaataag tatgtataac
     9241 attataaata caaagatatt aacatgtgta taagatgtta atatctttgt tattttagac
     9301 ttgataattt gttaataatt tttgttcaaa aaaagtatta acaggttatt caagagatat
     9361 aaacatacaa ttgtgtataa attatccctt caaatctgat ataattttgt ctattttagt
     9421 cttaatttct tcactttctt ctatatcctt agatactttg tcatgagcat gaattactgt
     9481 tgtatggtct ctacccccaa actcttcacc tattttagga agggataaat cagtaagctc
     9541 gcgcgttaaa tacatagcta tctgtcttgg ataagctatt gaacgtgttc tttttttaga
     9601 attaaaatct tccatcttta aattgaatac agaagatact ttttctttta ttctgagaac
     9661 atttatttct tcatttttag aagttgttat aatatctttt aaagcttctg tagcaagatc
     9721 aaaagatatt accctattgc taagagaaga ataagcaacc actctagtta atgcaccttc
     9781 tagttccctt atgtttgact taatattttt tgctatatat gacataacct catttggcac
     9841 atctatacgt tctagttgag ccttttttct aagtatagca attcttgtct caaagtcagg
     9901 tgcttgaata tcagttataa gtcccatttc aaatctcgat cttagcctat cttctagtgt
     9961 aggtatgtct tttggcggtc tatcactaga tataattatt tgtttgtttg cttcatgaag
    10021 agtattgaat gtatggaaaa actcttcttg agttctttct tttcctgcta taaattgaat
    10081 atcgtcgatt agtaatacat ctacgtttct atatttattc ctaaattctt cgtttttatc
    10141 gtcttttata gagtttataa gttcattagt aaatttttct gaagaaacgt aaactacttt
    10201 tgagtctttt ttttgactaa caatatgatg acctatagca tgcattaggt gagtcttacc
    10261 taatccaact cctccataca aaaaaagtgg gttataagct ttagctggag attctgcaac
    10321 tgcaacgcat gcagcatgtg caaatctatt actattacca ataacgaatg tatcaaatgt
    10381 gtattttgga tttagattgg ggtaaagaac tctataattt aaatctgtgc tatcagaatt
    10441 taaatcagca acctcttttt cgctcaatac aaatttaata ttatattttt ttaatgacag
    10501 ttgactaata gcatcttcaa ttaaatgtaa atatctattc tctaagatat ctttattaaa
    10561 atcactagga gccagtaaga ttaaatcatt aagatgtatt tttaatggta cgatgttttt
    10621 aaaaaaggta ttaaaactta ctgaagttaa gtcacctttt attaattgta gggttttgtc
    10681 ccataaagaa actatatcca taatataaac ctccgaacag aataattaat attttccaca
    10741 aagttattaa cagaaaagca aaaatatata taaattttac agaataacta aatttatgga
    10801 taatggtgtt gataaattaa taatagtata aattattaaa aaaatatgaa aagatataaa
    10861 caatatgtag ataaagttat aaataacata aacatacaat aaatggtgat tataactaga
    10921 gtattgtcag taatcttaaa agttatacac aaaagtatcc acaagctgtg aataatttct
    10981 aataagttga taacatttat gcacattatc aacaagtata tttataatat caaaatatat
    11041 gtcaaacttc aatgatttgt aactaattta tccacaatat taactaattg ttgataaaaa
    11101 tataaacatg ttaaaattac tttatttgtg tatataattg aaaaaaataa tttagaataa
    11161 aattaaatag atttttacta gtattttcaa taaaaaaaat acataatata tatatggtag
    11221 attttgtgat ataagcgtcc caaaaactcg ttgacaacag tagtaaaagt atttataatt
    11281 atatgtgtta tgtttacttt gagggtaaag ttattatttt tataaacgga aaataaaatc
    11341 tgaaaggcgg tgcaaaataa tgagtaaaag aacttatcaa ccaaaaaaga gacaaagaag
    11401 taaagaacat ggtttcagaa aaagaatgaa gacgtctaac ggaagaaacg tgttaaagag
    11461 aagaagagct aaaggaagaa atagattaac tcattaatta caaaagggcc gctgcaaagg
    11521 tggccttttt gtgtaaataa ttacaattca tagctgtgtt tatggaggtt aactatggac
    11581 tttaatagga ctaaagggtt gaaaaaagac tctgatttta gaaaagtata taaacacggc
    11641 aaatcttttg caaacaaata tttagtaata tatatactta aaaataaatc agattatagt
    11701 agagtaggta tttctgtttc aaaaaaagta ggaaaagcta ttactaggaa tagagtaaga
    11761 agattaataa aagaagccta cagattaaat attgatgaaa aaattaagcc tggatatgat
    11821 atagtattta tagcaagggt atctagtaag gatgctactt ttaaagacat agacaagtct
    11881 ataaaaaatt tagttaaaag aacggatatt tctatttaat tgtatgctat aaatatggag
    11941 gttaatgact ttgaataaaa taatttatat attaaaggaa ataagtaagc atttatcgaa
    12001 tttatgtatt tatttagtga gattttatca aaagtatata tctcccttaa agggacctac
    12061 ctgtagattt tatccaactt gctcacaata ttcaatagag gcgtttaaga aatatggatt
    12121 tgtaaaaggt atgtatttaa cgataagaag acttttaaaa tgtcatcctt ttcatccagg
    12181 aggttacgac cctctaaaat aaaagagagt aactattagg aggtataaaa aaattgaata
    12241 taataggaaa tttcttagga ttgattctta aggtaatatt tgaatttgtt aatcattatg
    12301 gtatttctat aatacttttt acgatacttg taaagattat tttattacca ttaacaatta
    12361 agcagactaa gtcaacaaag gcaatgcaag atatacaacc tcgtataaaa gagatacaag
    12421 aaaaatataa aaataagcca gaaaaacaaa atgaagaaat tgttaagtta tatggagaag
    12481 ctaaaattaa tccactatct ggttgtttac ctttattaat acagtttcct atattaatag
    12541 gattatttag cgttttgaga gaaccagttg ctcatggcgt ttttgcaaac aaagctgcat
    12601 ttttagcagc tgacaatggg tttttatgga taaaaagctt aacatcacca gattatgtat
    12661 tagcagtatt ttcaggagca agtgcatatg tcatgcaaaa agtaatgaca ccaaaagatc
    12721 agttacaagg ctctatgaaa gtaatgacat atgtaatggc aggtatgtct ttctattggg
    12781 gatttatatt cccagcagga cttacattgt actggacagt aagtaactta ttctcaatag
    12841 ctcaatatta cttaataatg aatcctttaa aagctaaact ggctgctaac tctaaggagg
    12901 aaaaagttaa tgagaaaaag cctaaaatta ataaaaagta agagtaaaga ggaagctata
    12961 agtaaagcta tagcagagtt gaatttaaaa gcagaggata tagaagtaga aatacttgaa
    13021 aatccaagta aagggttttt aggttttata ggtgctaaag atggtactta tgaaattttt
    13081 gttatcgaga gggaagtaga tgtagctaaa aattttatag aggtaatgtt gaaaaatgca
    13141 aatgttgatg ccaaagtcaa tgtatctcaa aaagataatt taatcatggt tgatattgaa
    13201 ggcaaagaag ctgcaagttt aattggtaga agaggggaaa ctttagattc tattcaattt
    13261 ttgactggat tagctcttaa taaaataaat aaagattctc atacaagagt acttgtagat
    13321 atagaaaatt atagatcaaa acgagaagaa tctttaataa gatatgctaa taaagttgct
    13381 agagaagtag cgaaaacaag aaaaactaaa aaattagatt atatgaatcc atatgagaga
    13441 agaataatac attcagctct tcaaaatgac aaatatgtaa ttacatatag tgaaggaacc
    13501 gatccatata gaagattagt aattgagtgt aaaagataaa gtcaacctcc taaacattag
    13561 ggggttttat tttttaatat tattaaatca ttaatggttg gttaaatgta aatctatatg
    13621 taaaaaatta tgaattaaga ggtgataaat ttgtttatag atgatacaat tgcagcaata
    13681 gctacagcac ctggagaagg tggtataggt atacttagaa taagtggaga aaaagctttg
    13741 aaggttgcag aagaaatctt taaatctatg tctggaaaga gtattgaaga atacaataag
    13801 agaacattaa tatatggaaa tatagtggat aatgaaaatg taattgatga agttttattg
    13861 gcatatatga aaggaccaaa ttcctataca ggagaagatg ttatagaaat taattgccat
    13921 ggtggattta tttcggtaaa gaagatatta gaattaatac tatcaaaaga tgttagatta
    13981 gcagaggctg gtgagtttac taaaagagca ttcttaaatg gaagaataga tttatctcaa
    14041 gcagaggctg taattgatgt tataaaagcc aaaactgata tagctcatga agttgctcaa
    14101 aatcaattag agggttcttt atcaaagaag ataagagaat tgagagataa agtcactgag
    14161 atattagctc atgtagaagt tgctatagat tatcctgagg aagatattga gcatataaca
    14221 tatcaaactc ttaaagaaaa aactgatgaa cttaaaaaag acattaaaaa attatatgat
    14281 acagctgaaa gtggaaaaat acttagagaa ggcttaaaga cggtaattgt tgggaaacca
    14341 aatgtaggta aatcttcact acttaattct attttaggag agaatagagc aatagttact
    14401 gatataccag gaactactag agatgttata gaagagtttg taaacataaa aggtatacct
    14461 ttaaaaattg ttgacacagc aggtataaga gatactgatg atattgttga aaaaataggt
    14521 gttgaaaagt ctaaagaatc atttactagt gcagatttga tagtaatggt tttagatgca
    14581 tctagaaagt tgtcagaaga agatatagag atattagaaa aacttaagga taaacaaaca
    14641 atagtgctgt taaataagaa tgatttgaaa caagagattg aagaagaaaa aatacttaaa
    14701 tatgtagaaa ataatagtat aataaaaata tcagctttac aacaagaagg aatagaagaa
    14761 ttgcaagata aaatagagtc tatggtatat aaaggtagta tcaaaaataa ttctagttta
    14821 gtagtaacaa attcaagaca taaagatgca cttagtaaag catataaatc tgcaacagat
    14881 gctttaattg ctttggaaca aagtatgcca tttgactttg tagaagtcga tttaaaaaat
    14941 atatgggact atcttggata tattaatggt gatacagtaa cagaggattt actagataat
    15001 atattccata atttctgtat tggtaagtaa tgtacaaaag taaacttgtt tttattatag
    15061 agatttttaa aaaatttgaa gtgtttctca tgaaacatta attttgaaaa gaaaggaatt
    15121 ataaatgata aagtttgaag caggaaaata tgatgttata gtagtcggag caggacatgc
    15181 tggatgtgaa gctgctttgg ctactgcaag aatgggatat aaaactttga taataacaat
    15241 gtctttggat tccatagcat taatgccttg taatccatca attggaggga ctggtaaagg
    15301 tcaattagtt aaagaaatag atgccttagg cggtcagatg ggattaaata tagacaagac
    15361 atatatacaa agtagaatgt taaatactgc caaaggtcca gcggtacact ctttaagagc
    15421 acaagcagat aaatttaaat atcatgaaga aatgaaaaag acattagaag atgaaccaaa
    15481 tcttgatata gctatggatg aagttgtaga aatacttcat gaaggaaatg ttgtaatagg
    15541 agttggaact aaactaggat gttcatttaa atctaaagct gtaatattgg ccactggagt
    15601 ttatctgaac tcaaagatat atatgggtga agttgcattt tatgaaggtc ctaatgcatt
    15661 agggtatgca aaatatctta cagatagctt agttgagctt ggccttagaa tgagaagatt
    15721 taagacggga actccagcaa gagttcatag agatagtata gacttctctg taatgtcttt
    15781 acaagagggt gatgaaaaag taactccatt ctcatttatg aatgaaaata tagaaaaaaa
    15841 acaagaacct tgttatttaa caagaactac agaagaaact caaaaagtta tactggataa
    15901 tttaaaaagg tctgctatgt atagtggagt aatagaaagt actggtccaa gatactgtcc
    15961 ttctatagaa gataaagtag taagatttag tgataaaaca tcacatcaat tatttataga
    16021 accagaaggg ttaaatacta aagaaatgta tatacaagga atttcaacta gtttaccttt
    16081 tgaagttcaa ttagatatgt acaaaactat aaaaggactt gaaaattgta agataatgag
    16141 acctgcatat gctattgaat atgattgtgt tgacccaact caactaaaaa taagtttgga
    16201 aataaagggt gttgagaact tatttagtgc agggcaattt aatggaactt ctggatacga
    16261 ggaagcagca gctcaagggc ttatggctgg tataaatgca gttagaaaga tagaaggaaa
    16321 agagccattt gtattagacc gttcagaagc ttatataggt gtcttattag atgaccttgt
    16381 tactaaagga actaacgagc cttacagaat gatgacatca agagcagaat atcgactata
    16441 tttaagacaa gataatgcag atatgagatt aactcaaaaa ggttatgata taggattagt
    16501 taaaaaagat agatatgaaa ggttcctaaa taaaaaggct gctgtagaga aagaatttga
    16561 aagactaaaa aatgaaagag ttacaccaaa agaagtaaat agtttgttgg aagaaaaagg
    16621 agcaacacca ataaaggttg gaatatctct atatgaattt ttaaagagac cagaggttac
    16681 ttacgaattg cttgaagaat tagggaaagg cgctggagaa gatgtttcaa gagaagttaa
    16741 agaacagtgt gtaataataa ctaaatatga aggttatata gagaaacaat tgaaacaaat
    16801 agaccaattt aaaaaacttg agaataaaaa gttggatgag aaaataaatt attcatctat
    16861 agaaggtctt agattagaag ctagacagaa attagatgat ataaaaccta tttcaatagg
    16921 gcaagcatct cgtatatctg gtgtttctcc agctgatata tcagttttac ttatatacct
    16981 agaacaaatc agaagaacta gaggtggcaa aggtgaataa tatagaactt ctgaaaaacg
    17041 ggattgaagg ttttaatata gatacgaatg acagtatgtt agaaaaattt aaaatctata
    17101 gagagatatt agttgaatgg aataaaaaga tgaatcttac tggaatagaa gatgaaaaag
    17161 aagtgtatat aaaacatttt ttagactcta tttcagctgt aaaaaatgga tatataaaaa
    17221 atgggatgtc tataatagat gttggtacag gtgctggttt tcctggaata ccattgaaaa
    17281 tatgtttaga tagcttagaa cttactttgt tagattcgtt aaataaaaga ataaactttt
    17341 tagaggaagt tagtagagta ctagagttag ataatattac atttatacat ggaagagctg
    17401 aagattttgg taaaaatgaa gactataggg aaaaatatga tgttgctacg gcaagagctg
    17461 ttgctggatt accgattctt atggaatttt gtgtaccatt tgtaaaagtt ggagggtatt
    17521 ttatttgctt aaaaggtccg aatgctaatt tagagctaga agaatcacaa aaggctattg
    17581 atgttttagg attggagtat attgaaaaaa tagatgtaga gttaccagag gtagatttaa
    17641 atcataatat attagttttt aaaaaagtga tggaaacacc agttaagtac cctagaaaag
    17701 ctggtaaacc agccaaaaat cctattaagt aatgaaaaat ttattattgg taagcttaat
    17761 tatttctcag gaaataatta agcttactgt aaaaaaacaa aaataaagga attattaaag
    17821 tagatgcaga aataaatttg tatgtacata tagagaacaa aaataattta tatctaaaat
    17881 aagagaggta tgttatggaa gataaaagag ttatggagat acctatagaa gatgtagttc
    17941 caaatccata tcaaccaaga aaaatatttt cacaagtttc attggaggaa ttgagcaatt
    18001 ctataaaggt atatggtata attcaaccta taacagttag agcaaaagat ggcaaatatg
    18061 aactaattgc aggagaaaga agattaagag cagctaaatt agcagagctt aaaaccatac
    18121 cagcaattat aaataatatg aacgatgaat cttctgctgt tctagcgtta ttagaaaatt
    18181 tgcaacgaga agacttaaat ttcattgaag aagcaattgg ttatgaaaac ttaataaaag
    18241 aacatgcttt tactcaacag caattagcag aaaaattggg caaaaatcaa tctactgtag
    18301 caaataagct tagaatatta aagcttccaa acgatataaa aatgaagcta atagagaata
    18361 atttaacaga aagacatgct agagcatttc ttaaactacc aagtgaagat ttaatgcaaa
    18421 gtgtgttaga caaagtcata aaaaatgaat tgactgttaa aaaaacagaa aaattgatac
    18481 aagatgtatt agaagaaact aaagttcaag aagagcctga taaaaaacag aatataaagg
    18541 gtgctatgag tataagaatt tacataaata ctataaagca ggcctttgat gctatatcaa
    18601 atacaggaat tgatgctaag tataatgaaa tagataaggg agattatatg gaagttgttg
    18661 taaaaatccc taaaaaatag agattactgc ttaccagtaa tctttttttg taatataagc
    18721 cttgtaatat aaattgattt atagacatta tttatactta aaaaacacct attcaacatt
    18781 taaaattaat ttaattctta aaggggggaa catcatgggc aaagttatag ctgtattcaa
    18841 tcaaaagggt ggagtcggga aaactacaac aaatgtaaat ttaagtgcta gcttaggaac
    18901 tttgggaaag aaaatattag tattagattt agacccacaa ggaaatacaa ctagtggata
    18961 tggtattaat aaaaacgaag tagaaaatac aatctatgaa attatgttag atgggttaca
    19021 tattaaagaa gcaataataa gtactgaatt tgagaatgta gatgtagttc catcagctac
    19081 tgaactatca ggtgcagaga tagagcttac atctaaaact aatagagagt atattttaaa
    19141 aaattccata aaagcggtaa tagatgaata tgattatata tttttagatt gtccaccctc
    19201 actggggatg cttacaataa attgtttaac tgctgtagat agtgttttaa ttccaataca
    19261 atgtgaatat tatgctttag aaggtgttag tcaattaatg gagactataa aattagtaaa
    19321 atcaagatta aatgctgata tagaaattca aggtgttgtt ttaagtatgt ttgatggaag
    19381 agctaattta tcaatacaag tagttgaaga agttaagaaa tactttaaag gtagtgtata
    19441 tacaacttta attccaagaa atgtaagact tgcagaagct ccaagtcatg gaaaacctgt
    19501 aatttattat gataaaagat gtagagggtc tgtagcttat ttggagttag cagaagaatt
    19561 tatagattta gaagaggagg aatggtagta tggagaataa gtctaaaaga agtaatagat
    19621 taggtagagg tcttagtgca ttgataccag aaattaaagg agaaacttca gaaaaagaaa
    19681 tagtcaacat agatatagac aaaatatatc caaacgaagt tcaacctaga aagcaatttg
    19741 atgaagaaaa gataaaagta ttgtcggact ctataaaaaa ttatggtgtt ttacagccaa
    19801 tagtggttaa aatggatgaa aataataaat atatgataat agctggagaa agaagattta
    19861 gagcatcaaa acttgcaaat aaaaatcaaa tacctgctat aattaaagat atagatatga
    19921 aagatataat ggagatagcc ttaattgaaa acttacagag ggaagattta aattcaatag
    19981 aagaggctct agcatataag agtttaatag agcattacaa tgtaactcag gaagaaatat
    20041 cagaagctgt tgggaagagt agacctcata taactaatac actaagactt ttaaatcttg
    20101 gacaagatgt tatagaaatg atagacagtg gtagaattac agcaggccat ggtaaggctt
    20161 tattgagaat tgcagataaa gatttgcaac ttcaaatagc gaaaaaaata gaagaagaag
    20221 aactttctgt aagagaagtc gaaaatatag ctaaaaaaat atctgaaaat aaacaagaag
    20281 aacctaaaaa atctaaacct aaggatgtat ttattttaga tgttgaagat aaacttagaa
    20341 atatatttgg aacaaaggtg aatatttcta aaggaaagaa aaaaggtaaa atagagatag
    20401 aatactataa tgatgatgat ttaaatagta ttgtatcaat gcttcttgaa tagaacaaaa
    20461 atataaaaca gagaggaaga ttgttatgat ttatttagat aatgctgcaa ctacatatcc
    20521 aaaaccagaa agagtgtata atgctgtttt agattgtatg aaaaattatt gtgcaaatcc
    20581 aggtagagca ggccataaac ttgctatgag agctgctagg gagatatatg atacaagaga
    20641 gaatatagct aagttgttca atgtaagtaa tcctatgaat atagtattta catctaatgc
    20701 aacagattct ttaaatttag cgataaaagg tgtattacaa gaaggagacc atgtaataac
    20761 aacgtctatg gagcataatt cagtaataag acctataaaa gcattggaaa aaaggggtat
    20821 tgaaaatact gtagtaaaat gcgattatga gggattttta gattatgaag atttagagaa
    20881 atcaataaag aataatacta aattgattgt aacaacacat gcgtctaatg tatgtggaac
    20941 tttaatagat ataaaaaaag ttggagaaat agctaaaaaa cataatatac tatttttagt
    21001 agatgcatca caaacagcag gtgtttatga tatagacgta aatgaatgta atatagatat
    21061 gttggcaatg ccaggtcata aatgcttatt tggacctcaa ggaacaggta tattatatgt
    21121 aagagaaggg ttgaacttaa atatattaaa agaaggtgga acaggtagta aatcagaaga
    21181 aatagttcaa ccagagttat tcccagataa atatgaatca ggaactcata atactccagg
    21241 tatagcaggt cttaaccaag gtatactatt tatatttgaa agaggaatca acaatataag
    21301 acaacatgaa gaagaattat gtcaatatat gatagacaaa ttagaggaag taccagatat
    21361 aaagatatat ggaccaaagg acagtaaaaa aagagcatca gtaatagctc taaatatagg
    21421 agatatggat tctggagagg ttactttctt attagatagt gattataata tagcgactag
    21481 atcaggaata cattgttcac cactagcaca taccacttta ggtactttaa aacaaggtgc
    21541 agtaaggttc agtataggat atttcaacac aaaagatgag atagataaag cagtggaagc
    21601 tttgaaaaaa atttcaaaaa ataaatagca tgagatttaa taatatagaa ataaaaaagg
    21661 ggatatttca aaataaaaat ttgaatcatc tccttttttg tacaaaaaag aaaaggggtc
    21721 cctaagaacc tctaatctat ttgataattg ttttaagaag ttactttaag taatctcctt
    21781 cttcaagaac tatatgacca ctttcgtaat tagaaccatc aacagtaatt tttatttgtt
    21841 caacattcat attttttatg taagtacgag caactgaatc aagcattaaa gtttctgcat
    21901 cactacctaa gtttgacttt gtaaagtcag agctaacatc taatatacca gtttttacac
    21961 catcaatgtc ttttgtagta aatgaattta attttgcaga ttctggaaca actttaagtt
    22021 tttgaagttc ttcaaataaa gtgttctcat caattttatt taaatcaact ttattttcaa
    22081 ttaaatctgt cttatctaca tcaaaagagt aaatagtagc tgattgagtt ttagtttctt
    22141 cttttggagt aggtttagct ttgttattag gaacctcttt ttcagtattg ttttcttctt
    22201 ttggttgttc aacatttgta ttattcttag tttctttttt agatgaatca cttccatttt
    22261 gagcattagt acaaccaact gcgaatatag atatagataa tatacttaac actaacatta
    22321 ttttcttatt tttcataaaa atttctcctc tcttaaaaac tattcttata tataattata
    22381 gtcgttatga gcaaatatat gaatacaaaa tagtaacaaa tttaaaaaat gatttattta
    22441 aattaataaa actcaaaata aactaaattt tagtcatttt tatgggaaat catttaatgt
    22501 acagtgaaaa tattgtaaaa taaaagtagt gtttttaaaa taaatataag ttataattat
    22561 attataaaaa aatgtcttca aaaggtggga atagtatgga aattttgagc ttaggagaaa
    22621 agattaaaaa attaagaaaa gaaaaaaaca tgacattaaa agaattagct ggagatagga
    22681 taacagcagc acaaataagc catatagaga gggataaatc tcatactagt tatgaactgt
    22741 tggaatatct aggcgataag ctagatgtaa gtgtagaata cttattagag accaaggaaa
    22801 tgcaatcaaa aaagataact gataatttaa tactacagag cgaaatttat ataaaagaaa
    22861 atgaattaaa caaggctgag gaccaaataa aagaagtttt agatatatgt aagagatacg
    22921 atttaatgga gaactatggc agatgtaatt ttttaatggc taatattaat ttgaaaaaat
    22981 ctaattataa tgatgctata gaaaactttg aaaaggcatt gtacttcttt ataaaaaata
    23041 gtgatagtga aaatatactt aagtgttatt taaacatagg gaaaatatat atgcaggaag
    23101 acttttataa aggtgctata agccacttta attttgcaga ggaaattttg tcagagaata
    23161 aatttgagga tgttaacata cacaaggaac tatatagtaa gatggcatat tgttacataa
    23221 aactagataa tccaaatatg tcattgaagt acatagaaaa gataaatgaa atagataata
    23281 gaaatgatag aaaagaagat gtcgatattt tggtgttaaa agcaaataat atgcttgaga
    23341 ttggaaaata tgaagaatca agagattact ttaaaaaagc actaaaaata cttgagagtg
    23401 aggataataa aactggatta gcaaatgtgt atttaacaat ttgtgatgtt tacagaaaaa
    23461 taggtgaaac agatagagta cttgaatatt cacaaaaggt atatgacata aagaaaaatg
    23521 atgaagatga atacatgatg tcaggattat ttaagataat agaagcatat atagataaag
    23581 aagattatga tttagctaga aaatattgta agatagcctt agcttcatca ataaaaaata
    23641 aaaataaatt caatgaatat aaagcattga gattctatgc taatatgtat aaaaatcaga
    23701 atgaagtaac tcttgcaatt gaatatctga ttaaatgcat aaaaatagta tcagatttag
    23761 gcaacaatag aatattggcc aatttatata tagacttagg tcaattatat tcaaatatat
    23821 caaaagaaaa agagttagaa tattatcaaa aaggtgtatt tatgtacaaa aacttagaaa
    23881 taatgtaggg taaataaacc tataagggta tagaaacaat ctataacaag caagataata
    23941 tctatgataa aatataaatt gtatgaatat ttttaaggag atgaatcaga caatgagtat
    24001 aaaaatagat gcgagagggc ttgcttgtcc taaaccagtt ataaatacaa aaagagaatt
    24061 ggataaccta gaagaaggtg ttgtagttac aatagttgat aatgaaacag ctaaggagaa
    24121 tatattaaaa cttgctaaat ctttaagttg tgaagcaaat attgttgacg aaaaagagaa
    24181 ttttatatct atagaaatta gaaaaggtaa aaatatacta gataaacaaa atgttgtaga
    24241 taataaagaa agtgaattag acaatacatg tatatttata tcttcagata agatgggact
    24301 tggaaatgac gaattaggaa aagtgttaat aaaaggattt atatatacat taacagaatc
    24361 taaaccttat cctaagtatg tacttttagt taatggagga gtaaaattaa gtgctgaaaa
    24421 tgaagaaacc atagaaaatc taaaaatact tgagaatatg ggtgtagaag ttttatcttg
    24481 tggtacttgt ttagattatt ataatttaaa agacaaatta caagtaggta cagttacaaa
    24541 tatgtatact atagttgaga cattaaagaa tgcatcaaat accatttcta tataatatat
    24601 gtatgtttaa taatataaaa ctaacaataa agattaactc aaatagatag tcagaaagga
    24661 ttaagtaatg aatcaaatgt atatagtgtc atttaattcg acacatcatg cgataagatc
    24721 agaaaagtta tttggtgaaa atagtctaaa agtaatggct cttccaacac caagagaaat
    24781 aacagcaagt tgtggaatat caattaaatt ttcttttgaa gatatggaaa agataaaaac
    24841 tattttggtt gaaaataatg tagatataaa aggaatttat tgtataagta aattagaaaa
    24901 tggttcaaaa gaagtagaga agttagatta ggaggctaat tatttatgcc aatggattta
    24961 aaaataggtg atattgttga attaaaaaag caacatgcat gtgggtgtaa agagtttgaa
    25021 atcataagaa cgggaatgga tataaagata aaatgtacta aatgttcaag gctaataatg
    25081 cttgatagag agaccttaga aaagagagta aaaaagctaa taaaaaagtg ataaaaattt
    25141 aacacttaaa aaatgtcaaa taccgtatat taatatccaa aattttggta taataagaat
    25201 tgaagaaaac attttcatgg gggtgcttta attatggcag ttaaatatgc aaaaagaatg
    25261 caaggattac aaggatcaga aatacgtgag cttttaaaac ttactcaaca accacaaata
    25321 atatcttttg ctggtggaat gccggctcca gagttatttc cagttgagga aatgaaaaaa
    25381 gtatcagttg cagtgcttga agaaaatgga agatcagcta tgcaatatac tacaacagaa
    25441 ggatatgaac cattaagaga aaaaatagca gctagaatga atgataaaaa caaaactaat
    25501 gtaaacaaag atgatatatt agttacaagt ggttctcaac aaggtctaga ttttgcagga
    25561 aaagtattta ttgatgaggg tgatgtaatt ttatgtgaaa gtccatctta cataggagct
    25621 ataaacgcat ttaaatctta tcaacctaaa ttcatagatg ttccaacaga ttctgatgga
    25681 atgataatgg aagaattaga aaagatacta gaaacaactg atagaataaa aatgatttac
    25741 gtaatacctg acttccaaaa tccaacagga agaacttggc cacttgaaag acgtaaaaaa
    25801 ttcatggaaa tagtaaataa atttgaaata ccagtaatag aagataatcc atatggagat
    25861 ttaagatttg aaggagagac tttaccatct ttaaaatcaa tggatacaaa aggattagta
    25921 atattcttag gaactttctc taaaatattc tgcccaggat acagattagg atggacttgt
    25981 gcttctccag aaattttatc taagtttaac tttgcaaaac aaggtgcaga cttacaagca
    26041 tcaactatat ctcaaatgga agtaagcaaa tttatggata tgtatgacct agatgcacat
    26101 gttgacaaaa taaaagcagt ttatgttaaa cgtagagatg taatgcttaa gactatggaa
    26161 gaagagttcc cagaaggatt agtatttact catccagaag gtggattatt tacatgggta
    26221 gagcttccaa gtaatttaaa tgctaaagaa ttaatgccaa aatgtttaga taagaatgtt
    26281 gcttatgttg ctggaggagg attcttccct aatggtggta gagaaaatac tttcagactt
    26341 aactattcaa atatgccaga agaaaaaata atagaaggta taaaaaatat agcagctgta
    26401 ttaaaagaag ctatgggtgt agaagcttaa ttaaaaataa taacttatat ataatacaag
    26461 ggatggttgt tgccatccct tgtttgtttg aaaagtatat aattcacctt atactaaact
    26521 ttgtccaaaa tttaaattga cagaaataag aataaatgat aaaatgtgta ggtatgagat
    26581 tttagtctca tttctctgct ctaagagtgt agagccgtta agtccaaagg gaggtgaatt
    26641 atagtgagaa attatgaatt agtttatgtg gtaaagccaa actctgatga agaagtaaga
    26701 gaggctatac taaacaaagt taaggaagtt gttgcaactg acggagaaat agttaaagtt
    26761 gatacttggg gaactaaaaa attagcttat ccaatagcta agtttacaga aggtttctat
    26821 gtattagtta acttcaaatc agcagtagac gttcctaaag agatagacag aaacttaaag
    26881 ataaatgaaa acgtaataag acacatgata gttgttgctt aataactggt tttattataa
    26941 aaaataggtg gtgtttttat gaatcaagtt gtattagtgg gaaggttgac tagagaccct
    27001 gaattaagat acatcccagg tacaggaaca ccagtggcat cctttacaat agccattgat
    27061 agagactatg taaaaaaaga tggatctaaa gaaactgatt ttatacctgt tgaagtaatg
    27121 ggtaaatctg ctgaattttg tgctaactac ataactaaag gtagattagt agcacttcaa
    27181 ggatctataa gagtagacaa ttatcagaca caatcaggtg aaaagagaac ttttacaaaa
    27241 gtaagtacta gatcagtaca agctttggat agtaagaata aatcggaaaa ttcatataga
    27301 gagagtgctc cagcttttga gccaagcttt gaacctcaag gtttagaccc acaaggtttc
    27361 caagctatag atgatgacga tataccattt taaaaaggag ggaaaaaagt catgatgaat
    27421 aaaaaaagac gtaagaaaaa aagagtttgt caattttgtg ctgacaaaaa cgctaaaata
    27481 gattacaaaa gtactcaaag attacaaaag tatataactg aaagaggaaa gatattacca
    27541 agaagaatat ctggaacttg tgctaagcat caaagagaat taacagttgc tataaaaaga
    27601 gcgagaaata tagcactttt accatataca ttagactaaa aaaatgagcc ttgtgctcat
    27661 tttttattat atgtatttat atatctaaat gaggcgagct ataaagctcg tttttttgtt
    27721 tatatactta aatatattat tatttatgat ataatattat atattaagga gggttgtaaa
    27781 cgtgaaaata gataaaggtt ctgagataac gagaaacata aagataatag aatggatgaa
    27841 aacagaaata ttaatgagtg taagtgattt gtttaattta ttgtttaaag gggtaaaacc
    27901 attagatgaa gcaattcaag atactttagc aaatataata atgataacat atctcttagc
    27961 aaagagatta ggaattagtt ttagagatgt ggattataaa gtcaaggaaa aaataaaaat
    28021 tggtatagat gaggaccata gcgttgaaag atggtatgga gatttatcta atttaaaaaa
    28081 acatatggat aatagggagt gatattaaat tgaataataa aattagacta tctaaggcaa
    28141 tgtctataat agttttagct ataataatcg ctttagtaat agcctatatt ccaatgctag
    28201 gaatatttag tatgttagca gctgttccat atgtaattat aggtgctatt actgatagaa
    28261 agtattctct tatatctatt ttggttacat tttgtgtact gattctattt gcagacattt
    28321 cttatgcatt aaatatatgt ataatgtatt ctttaccagg tatagtaata ggaaagatgc
    28381 taaagagaag ctttgaacaa gaggacagta ataaattcga accgatatat ggtggaacca
    28441 taatatttgt actttcaatg cttgtatatt tttttgtatt aaagacattt ttaaatgtga
    28501 atctattaga tgaagtttct aagatgatat cagaaattgt aaatattcaa aaaaatagtt
    28561 tttctgcaac tgaacttaaa gtgtttgata aaatgaagcc agatgagatt gtaagttatt
    28621 ttacaaatat gctaccaatg atgttatttt tacaagggtt gttatcagcg tttgtcacat
    28681 attatttgag tgtatttttt ataaaaagga ttacaaagat gaatataaga tttcctaagt
    28741 ttgctgattt ttatttaccg ggaaatgcta tactcacaac tttcttactt tatttattag
    28801 tcttatttat tcaaattatt ggttcaaaat tatatacaga attaataatg actaatttac
    28861 agctagtttt taatttaatg tttgtaattc aaggtatagc agtttgcatt tatttcttaa
    28921 agaaatggat aagacaggga ccaaataaaa ttatgttttt ttcagggata attttatgtt
    28981 tatttggatt tatgggaata tcttttgttg gtatggtaga tagtataatt gactttagaa
    29041 aggtaagaag ctataaatcc acttaggagg atagaaatga gtaataaaca aacctttaaa
    29101 ttaaatatgc cagaaataaa tttatatata attgttattg gtatttctag tataattttg
    29161 ctttattaca acttgtatgt agggtgttta tttttctgta tttttgtata tatggttttt
    29221 cacaattgga gaactactaa tattagacgt catgaatgga cagagtatat tcaaaattta
    29281 tctttagata tagatgaaac aactaaaaaa gccataataa atcttccaat accattatgt
    29341 attttagaat ttgatggaaa tatatcctgg tataatggaa agttttatga tatgattggt
    29401 caaaaagatt tacttgataa aaatatagag gatatagtta aaaatcttaa tttaagaaaa
    29461 gtattaaatg aaaataaaga gatgtacaca gaaataaact ataaagaaaa agaatataca
    29521 ataatttata atgttataaa aaatgatcaa gaaaaaaatc ctaaatattt gatgatatta
    29581 tactggatag acaagactga atatttaaaa gtaaaacaaa attatgatga tgaaaaaaat
    29641 gcaatgatgc taatacaagt agatggatat gatgaagtat taaaaagtgc agcagaagat
    29701 aagagagctt taattaatgt tgaagtagag aaaatacttt ctgctttaga attaaattca
    29761 aatggtgcat tgagaagaac ttcaaaagac aaattcttct tggtaatgca taaaaaagag
    29821 ttaaaaaaat tggaagctga gaagttttct attttagata caataagaca tattgattat
    29881 ggaaataatc ttcctgttac tataagtata ggaattggta tagatggaga tacattaaat
    29941 gagaacctaa aacttgctac gggtgctctc gatttagcac ttggtagagg tggtgaccag
    30001 gctgttgtaa aaacaaaaga taaatttgtg ttttatggag gaaaatctaa agctgtagaa
    30061 aagaaaacca aagtaaaatc cagattaata ggtcatgctt taagagaggt tatacaacaa
    30121 agtgaccaag tttatataat gggacataaa tatcctgata tggatgctat gggagcagca
    30181 gttggtgttt atgatatatg taaatcctgt aacaaaactg caaacatagt tttacaatct
    30241 gtaaatgaat ctatagaaat atttataaat aaaataaatg aaaataatta ctataaaaag
    30301 ttgtttattg gaaaagagga agctattgac aactgcacta aaaatacatt agttgtagta
    30361 gttgatactc atagaccaaa ttatactgaa tgtgaagaac tgttaaagct atcagagaag
    30421 gtagtagtta tagaccatca tagaagaggt gtagagttta taaatgatgc agtgctttta
    30481 ttccatgaga tatatgtatc ctcaacgtgt gaaatggtta cagagttagt tcagtatatg
    30541 gatgaagatg taacaataaa taaacttaca gctgaagggc ttttagcagg tataagtcta
    30601 gatactaaaa actttgcatt caaaacaggt gttagaactt ttgaagctgc ttcttacctt
    30661 agaaaagttg gagcagatac tatagaggta aagaaattct tcaattctga tgtaaaagat
    30721 ttcataataa aagctgaaat aattcaaagt actaaaataa ttaataatag aatatgttta
    30781 gcatattcaa gtactgagat agatagtata aatgttataa tagctcaaac tgctgatgag
    30841 ttattgaata tcaaagaagt agaagcttcc tttgtattag gtgaaaaaga tgatactata
    30901 tttataagtg cgaggtcttt aggacaaata aatgtacatg tacttatgga aaaattagga
    30961 ggcgggggac acatagatat agctggagca cagttaaaaa atgtttctct aaaagaagct
    31021 tataagatgg taaataaaat aatagaggag tatttggagg aggaagaata gatgaaagtt
    31081 atattattaa aagacgtaaa aggaactggt aaaaagggag aaatgaaaga agtaagtgat
    31141 ggatatgcaa gaaatttctt atttcctaaa aagatggctg tgcaagcaga tagtgtagca
    31201 ataaaagaat taaatgaaaa gaataaatct aaagaaataa aagcacaaaa agagtatgaa
    31261 gaagcagttt tattaggtaa gcaaatggaa gaaattaata tagaaatata ttcaaaagca
    31321 ggagaaggtg gaagattatt tggttcaata acttctaaag aaattgctga gcaattaaag
    31381 aaacaaaaag acatagatgt agataaaaga aaaatattat tagatgagcc gataagatct
    31441 ttaggttcaa cttttgtaga aataaaaata catcaaaaag taactactaa aataagagtg
    31501 gatgtaaaag aaaaacagta ataactagag gtgattaaga tggaagatat gacgagaatt
    31561 cctcctcata gtgtagaatc agaacaatca atattgggtt ctatacttct agataaagat
    31621 gctataataa cggttacaga aactataaag cctgatgatt tctataaaga ggctcacaaa
    31681 ataatatatg aatgtatgat aactttaagt aataaaggtg agcctataga cttgataaca
    31741 ttaacagaag aactaagaaa acaagggcat cttaatgata ttggaggaat cagttatatt
    31801 acaagtcttt ctactatagt accgacgact tcaaatgtaa aatactatgc tgatatagta
    31861 aaagaaaagt ctgtacttag aaagcttata aaagcttcta atgaaataat aaatctagga
    31921 tatagtggag caactaagat tgaagatgtt ttagaacaag ctgaaaagag tatatttgat
    31981 atatcacagg agaaaactag tgatgatttt aaatctataa acttagtttt gatggatgcc
    32041 tatgatatga tagaaaaatt atacactaac aagagtgatg tcactggtat aactactggt
    32101 tttaaagatt taaacaaaaa aataaatggt cttcaaagga ctgatttaat attaattgca
    32161 gctagaccag caatgggtaa aactgccttt tctttaaact tggttcaaaa tgcagcctta
    32221 aaaggtgatg cctctgtagc tgtatttagt ttagagatgt ctaaggaaca attagtacaa
    32281 cgtatgttat cttcacaatc tagtgtagaa ttaaaaaaaa taaagactgg aacacttaat
    32341 gataatgatt ggcctagaat tatagatgct atggcagtat tatcagatgc caaaatacac
    32401 atagatgata ctcctggtat aaaaatatca gaactaaggt caaagtgtag aaagttaaaa
    32461 atagaaaaag gactagattt agtgcttatt gattatcttc aacttatgga aggtgaaggt
    32521 aataatgaaa gcagacaaca agagatatct aagatatcaa ggtcactaaa aatattagca
    32581 aaagaattaa actgtcctgt agtagcacta tctcagttat cacgtgcacc agaacaaaga
    32641 gcagaccata gacctatgtt atctgattta agagagtctg gagcaataga acaggatgca
    32701 gatatagtta tgttcttata cagggacgaa tattatcatg ctgattctga gagtaaaaat
    32761 ataggagaag taataatagc aaaaaataga cacggtgaaa ctggttctgt ggaacttgtt
    32821 tggcttggtg aagttcaaag atttggggat aagttgagag acctataatc taacgaatat
    32881 ccacagaacg tcctttcttt ctacaggaaa aatgtggata catgtcacta aatatgtcca
    32941 aacattgaaa tttagctaaa aaactatcca cactatccac agatggcctg ttgataagtg
    33001 tgaataagta gataaagcaa gcttttggct tgctttatct gtgtataaat attaattatt
    33061 aggaggaata atatggaaaa aataagctta aaatatatat atcccaatat aattaaagta
    33121 cttgatgaaa taaacttatt tagagtaatt gacaataatt taagagagtc tattgttgtt
    33181 tatgctaata atgtggataa tcagtatcat ataaacatga ctaatacaaa ctttggaaac
    33241 ataattaaca tatgtaaatt agaaaaactt ttagatgtgg ataaatttat ggaaaaagtt
    33301 ataaaatatg aaaaagaaat aatagagaaa gaagagtttt caaaaataga agaatatatg
    33361 ttaaatattg gagaatacta aaaaagttga aaaaaatacg aatgtttgat agaataagta
    33421 agtaaagtgt tcgagagtat ataaaatata gaggtgaatt acatgaaaac agttgcaatt
    33481 gttggttctc aatggggaga tgaaggtaaa ggtaaagtta tagattatct tgctactcaa
    33541 gcagatgtag tagtaagagg gcaaggtgga aataatgcag gacatacatt agttgtagaa
    33601 ggtaaaaaat atgcattaca tctaattcca tctggagttt taaatccaaa tacagtgaat
    33661 ataatcggaa atggaatagt gtttgaccct aaaggatttt tagaagaatt ggaaatgttt
    33721 aaaacggata atataagtac agaaaatata aaaataagtg atagagcaca tgtcatattc
    33781 ccatatcata aagaactaga tgcattgtca gaagaagcca gaggcgattt aaagataggt
    33841 acaacaaaaa aaggtattgg accttgttat atggataaaa cagagagatc tggtattaga
    33901 atatgtgact taatggataa agataaattt gctataaaat taaaagctca aatagatgct
    33961 aaaaatgaaa tagttaaaaa tatatatgga aaagaagaat tatttgattt tgaaactata
    34021 tataacgaat atctaggata tgcagaacaa ataagaaaat atgtggcaga tacgtctgtt
    34081 attgtatatg atgcagtaag agcaggtaaa aaagtattgt ttgaaggagc acaagggact
    34141 ttattagatt tagatttagg aacttatcca tttgttacat cttctcatcc aacatctggt
    34201 ggatttgcaa ttggtgcagg tataggacca aatatgataa aagacgttgt tggtatagta
    34261 aaagcatata ctacaagagt tggagaagga ccgtttgtta cagagcaaat aaatgaaact
    34321 ggagataaga taagagaaca aggacatgaa tttggggtaa ctactggtag accaagaaga
    34381 tgtgggtggt ttgatgcagt tatagttaag tattcagcta gagttaatgg attgactagt
    34441 atttcattta tgttacttga tgtattaact ggatttgata agataaaagt ttgtacgtct
    34501 tataaaatgg gcgataagat aataacggat ttcccagctt cattagatga tttagcaaaa
    34561 tgtgaacctg tatatgaaga attagatgga tggaatgaag atataactca aatagataac
    34621 tttgatgacc ttccagaaaa tgcaaagaaa tatgtagcaa aaatagaaga actagttgga
    34681 gtaagtgtag atatggtttc tgttggtcca aatagagctc aaactataat aagaagaaat
    34741 atatttgctt aatattttat caattaaata atttaaaata gttgaagaag agtatctcaa
    34801 gataatgttt atagttatta gagatgctct tttatatttg acttacattg attttttatt
    34861 aagttaaagc tacttataca tattctaact gaaattaaag ttgaatttat gtagatacag
    34921 ataggttttt taaaaagaat tttgttgaaa ataaatggct aaagatgatt ttaattatat
    34981 tctaaaaaaa gtaaaaaaaa ctattgacta aaaattatat agacgctata atataacttg
    35041 tgagtgaaag aaacgacgaa aaaagtcgaa aaaatgtggt ctattagctc agtcggtaga
    35101 gcacctgact tttaatcagg gtgtcccgcg ttcgagtcgc ggatagatca ccaaaatatg
    35161 gctcgttggt caagaggtta agacaccgcc ctttcacggc ggtaacaggg gttcaattcc
    35221 cctacgagtc accagtatgg gactatagct cagctgggag agcacctgcc ttacaagcag
    35281 ggggtcacag gttcgagccc tgttagtccc accaaatttt gaattagaga taaatactag
    35341 attatatgct ggtgtggctc aacggtagag cagctgactt gtaatcagca ggttgtaggt
    35401 tcgattccta tcaccagctc cacaaagtac ataaattcaa attaatataa ttttctatgt
    35461 tacaggatac ttttaagtat ctttttttaa tttcattttt attgtattaa aaatgaaatt
    35521 aaacatacaa caaaattttg aattacttgc aatgtgatag ttttaaatat aaaatttaga
    35581 atcattctag catagtatta tgtaatatag caaatttaat ttatagtatc aataaatata
    35641 gactactaag aatgtaatga tttgttagat taagatacat tagatatgta aatagaaaaa
    35701 taaaaagtat gttttaattt atgtggcata agttttaaac agagaagcaa gtttgctctt
    35761 acctctctat ttaaaaataa aaaaatgttt tttaagggct attttattta aatctttccc
    35821 atctcaaatc atctccagta aattctaaaa tcctaaactt atctaagatt ctagagagag
    35881 ttctttgagt gtaagtattt cctatttgag atggtgttaa gttggttgaa ataatgattt
    35941 ttttaccagc aacaagtctt gtatttacaa tattgaagat ttctccacta gtaaaagaat
    36001 tattaagttc agttccaagg tcatctatta ttaataaatc acaatcaaac aagtttttat
    36061 aattatcttc acttatttga ttatttgtgt ctcttctaaa tttataatct tcaagaatat
    36121 ctaaaattct aaaagaagtt tgatagatta caacattgcc tttatctaac aattcctttg
    36181 caatacaatt gcacatatag gtctttccta gtccagtaga accataaaac agtagatttt
    36241 cactattatc cttcttaaaa tcatgaacaa aattttcgca gatacttaaa ttatttagca
    36301 tattttctct aggagatatt tcaccatcag agcctttctt aggagaaaat atattcaagt
    36361 taaaattcga aaaattttcc tgacttaaaa tcctatctaa attagacatt ttataagctt
    36421 catttacaat ttcttgtttg aggcaagaac atttttctcc attaggtaaa aatcctttat
    36481 ctttacaaga aatacattga aactttattt ccaagtaatc aagaggtatg ttactttcag
    36541 ctaaaagtct ttctttcttt acttttaaag actctatatt ctctttagtc ttctttacaa
    36601 tttcatcttt agacttggga tttaaaagta ctatcttagc taaactgaga cctattttag
    36661 aaatttcatc atctatagat tttatctcag ggattctatt atatacctca ttttttctat
    36721 gttctaataa gagttcatta tcatctcttc tcttagcata tttagcaagt atttttctta
    36781 ttttatcctc attcatttaa tcacctactt aaacttttct ttttgacttt ttttaataat
    36841 ctcatcgagc tcatcagagg tatactgagt gaatgtttcg ttgaaattat gaaacttagt
    36901 ttttttgtaa gtattgttgt tttgagtagt attaatctgc ttcttattaa tattctcctt
    36961 aactatacgt tcttcctctt tttgctttaa atcatttaaa ttttttatat ttttttcatt
    37021 ccaattttta attatgccat ttatataaga tatacttggg tttgaaatat tcttagactt
    37081 agaacatgca tttattatca aatctatatc catattaaat ttatcaaacc aggtgtccat
    37141 aagttctttt tctgattttg atggttgtct tgaaaatccc aattcattga aaatcgtttt
    37201 atataaaata tatcgttcac ttcttaccaa aaagctttct tcaacatctt ttggcgtata
    37261 taaatttgaa tcataccaat ttctaataat gccttcaatg tatttaactg gctttgatgt
    37321 accagtttta tctttgacgt attcatatgc gcaaagtatc atatcggggc tcatattgta
    37381 tttattcatt atatccataa tactcatctt ttcacttggg tcgagatatc gcccaactat
    37441 tttatttata gaattaaaca tttttctaat acttggattt tcagaagtag atacaacctt
    37501 atctgtatta gattttatag atgaattatt gcttaatata ttctcaatat agaaattttt
    37561 taaatctaaa aattctattg aataattaaa attatcatat tctccattgt catgtatttt
    37621 tataatcttc ttttcttccc agaatttcca agcagataac acatcagaca atggtatatt
    37681 taggtttttg gctattgaat tattgtcgaa cttaggatta gaagtaatat cacatgcttg
    37741 tctatatcct aaaagataaa cttttacgta taacccgtcc gccattggca taaatatatc
    37801 tataaagata ttgggaatag tgatttcacc taaatctatt tcattgcttt ctttaaaaaa
    37861 cattttatca cctcagatta aattatatca ttttttatat tatatttgtc tgtaaacaaa
    37921 taaaaggtca caagattagc atgtaaatat tttctaaaag tattcatttt gaaaaggagg
    37981 agatattttg gttataaaat tcaaccaaaa agtaagaaga acattatcag tagcgattct
    38041 atttatggta ttaataatag gttgctttat aaaaaaggat gacagtttag aaacatacaa
    38101 agaaaaaact aattcaaaaa taaatcagta taatatggat gttatatttg atgatgagac
    38161 taagaggtta atgtgcaatc agaatgttga ctacataaat aatacaaaat caaacataga
    38221 taaaatatat ttccatatat atccgaatgc tttttccaag aaagattttg ctccttttga
    38281 aaaaagtgaa atgacaaggg cttatcctaa tggatttaac gaaggatata tagatataaa
    38341 gaatatatta aataataata gtaaaatgga gtataaaatt aaaggagaca aaaatgacat
    38401 attagaaata gaattaggga aagagttaaa accaaatgaa agaatgtcat tagatataaa
    38461 atataacgta aaaataccaa attcaattgg aagatttgga tatggagaaa atactataaa
    38521 tgttactaat tggtttccta tagcttgtgt aaatgatgaa aggggatgga atttaaagag
    38581 ttatgaaact attggcgacc cattttatag tgagactagc gattttcatg tgaaactatt
    38641 gattccaaat aaatataaaa ttgctcatac aggaaaactt atttatgata aacatgataa
    38701 taagaaaatg ctatatgaaa tagaagctga aaacgttaga gattttgcat ttatactaag
    38761 tagtaaattt gatgtaaaca aagtagattc aaaaggagta gctatcaata catataattt
    38821 aaataaaaag ctttctaaaa aagcaactga agtggcaaaa gattcaataa atatatttag
    38881 tgaattattt ggaaagtatc cttacaaaga attttctgtt gtagcaagtg acttttttat
    38941 aggggggatg gaatacccta tgcttgttat gatagaccaa agtttatata atgaaaaaaa
    39001 tgaattttta ctagaatatg ttattgccca tgagacagca catcaatggt ggtattctgc
    39061 tgttggaaat gatgaaataa gtgaaccctg gttagatgaa gcacttactg aatattctac
    39121 aatagtttat tttgaacaaa agtatggtaa agatatggca aacaagctta taaaaactat
    39181 ggagatacag acaaaaagtt atttgagcga aaatatattt aagccagcaa atgagtataa
    39241 aaattctact gaatacagct tgaatgttta tacaaaaggc gcaatagcat ttaatgaaat
    39301 aagaaaagaa gttggagata aagtattctt tgagacttta aatgagtact ataataaata
    39361 taagcataaa aatgctaatg gaagagcctt tgtggaacta tggaatagta aaggtgtaga
    39421 tataaataag attataagtg aatgtaagta aacagtgaat gtaagtaaat tttgtgtaga
    39481 gtattaaatt ttatttaata ctctgttttt ttggtataat ataatttata aggcagaaaa
    39541 agaggtgaag gaatgctaaa gtattgttca gtagggagtg gtagtagtgg taattgccac
    39601 tatatagggt ataaaaatac taatatacta gtagatgcag gattaagtgg caagagaata
    39661 actacaggtc ttaaagacat tggtgtagat gcagataaat taaaaggaat atttataaca
    39721 catgagcatg ttgaccatat aaaaggagca ggtatattat caagaaagtt tgatatacca
    39781 gtatttgcta atataaaaac atggtgttct atgaaggaca aattaggtga catcaaagat
    39841 aagaatatga aagtatttga aaatgataaa acctactcat taggtgatat catagtaaga
    39901 cctttttcaa tagaacatga tgcgtctgac ccagttggat ataattttta tacagagagt
    39961 gatgaaaaaa tgtctatagc tactgatata ggatgtataa ctcaaaatat aaaaaaacat
    40021 ctatataaat ctaaattagt agtattggaa tcaaattatg accctaatat gcttatgatg
    40081 ggttcatata catatgcttt aaagaaaaga gtaatgtcaa gtactggtca tttatccaat
    40141 gaagatgcag ctaatttctg cgttgaactt attaatgaag gtacagaatc tatattatta
    40201 gcacatttga gtaaagaaaa taattttcct gagttagcgt atgagacttc aaaaggagta
    40261 ttagcatcaa atgatatagt agttggacaa gatgtaaaac tagatgtact atcacgaaat
    40321 gatgtttcta atgtttatga gatgaagtag aggtgaataa ctttgctaaa gagaaatttt
    40381 gaaaatgttg aggataataa aattttatac tctataaagc agggtatgat tttagcgata
    40441 cctgctatta tgactggttc aactgctctt gtaattttga atcttccaat aaaggcttat
    40501 caagaatatt tatcaggctt gtttaatgga gaggttacaa atattcttaa ctttataaat
    40561 gattctactt taggaattat ttcattaata atattattaa caataagcta tagttatgga
    40621 aaaatatatg ggagcaagta tacagtactt gttcctatag ttgcaatgtg ctctttttta
    40681 gtattttcac atggtaatga gcttaattct tatatagaaa tatttaaaac aaagtggtta
    40741 tttacatcta taattgtttc tatgacatct tctgtattgt ttgtaaaact tacagaatct
    40801 tttgttacaa gtgtaaagtt tcatacagaa ggggctgatg cagactttaa tatggtagtt
    40861 tcggctatag ttcctttcat aatagtagta tttttgtttt ctatttttag agtgataatg
    40921 ataagtctaa ttggcagttc aaactttcaa gatatatttt ataatttatt ttcaaatgtt
    40981 tttaataaaa tgggaacaaa ccttatgagt gctctgttgt ttattttttt aatgcacttt
    41041 atgtggtttt ttgggattca tggtagtaat gtattagata ccgtcgcaaa aaatttattt
    41101 gaaaatagta tggcaattaa cataaattta gttaataata atcaattacc aacagaaatt
    41161 tttactaaga ccttttttga tacaatggtt ttattgggag gatgtggctc tttactatgt
    41221 ttagtaattg caatttttct tagtgaaaaa cgtataaatg taagaaagtt agctaaaatt
    41281 gcttcaatac cagctctttt taatatcaat gagatgctag ttttcgggat accaattgtt
    41341 tttaactata ttatgtttgt accttttgta attactccta taatcttaac catcacaagt
    41401 tatgtggcta tgtctacagg tattgtacca tgtacagttt cagctgtaga atggacctca
    41461 cctatatttt taagtggata tatgtctaca ggttcaataa gaggtagttt gttgcaagta
    41521 tttaatttat gtgttggtgt tatgatttat attccgttta taaaaatgtc gcaaaataga
    41581 tatacatata tgtttaaaaa taatatagaa aatttaacaa acttattaaa aaggtatgaa
    41641 ttaacaggtg aacagcctaa tcttctaaac cataatggta aaataggttc aatttcaaaa
    41701 atgttggcat cagacttgaa gtttgctatg aaaagaggag aaatagagct tttttatcaa
    41761 ccacaagtca attataatgg aaatgttgtg ggagcagagg gattacttag atggaaacat
    41821 tcaataggag ggttcattta tccaccacta gttataattt tggctaaaga agaagggttc
    41881 ttagatgaac ttggagagta tattattaat aaagcatgta ttgatttaaa gaagagtgaa
    41941 aagctattga gaaatcctgt taagttctct gtaaatatat ctccagacca acttgatgac
    42001 cctaagttac cagagcaaat aaaaaatatc attagtagta atgatataaa tcctaatatg
    42061 ttaggtatag aaataacaga gcaaattgca ttatcaggtt cacaaataat tattgaacgt
    42121 atcaatgcga tacataactt gggaataaag ttaattatgg atgattttgg gatggggcat
    42181 agctctctta tatatcttca aaataataac tttgatatag ttaaattgga tggttcatta
    42241 gttaaagaga tacttacaaa taaaagaagt agtgaaatta taatgactat tgtaaatctt
    42301 tcaaaaaatt tagattttga tatagttgtt gagtatgttg aaaatataga ccaaagggat
    42361 aagttatatg gtttaggatg tgaaatatat caaggatatt attatagcaa agcaatacct
    42421 tttgaagagt ttgtagaata tgcaaatcaa gaaagagaga tataatttta taagagcttg
    42481 taaattctag taatgcatag atttgtaata aaattaagtt taggagaaat atatgaatat
    42541 aagtatagta gtagtaggta aaattaaaga aaaatattta aaattaggta ttgatgagtt
    42601 taagaaaagg ctttctaagt attgtaagtt agaaattata gagttggatg atgaaaaagc
    42661 tccagagaat ttgagtgtta aggaaatgga aattataaaa gacaaagaag gaaagaaaat
    42721 tttagggaag ataaagcata atagttatgt tatagccttg gctattgatg ggaaaggttt
    42781 atcctctgaa gaacttgcta agactatgag tgatttacca gttagaggta atagtagtct
    42841 ctgttttata ataggaggtt ctctagggct ttctgatgag gttttaggaa gggctgatta
    42901 taggttatcc ttttctagga tgacttttcc tcatcagatg atgagattga tattgttaga
    42961 acagatttat agggcttata ggataaataa tggagaaccg tatcacaagt aagtgcgaac
    43021 tttaccaaaa ttggatatat aaatgaaagg taggtctgct ttaattctgc aatgaaactc
    43081 acaaaaatct aaaatttgaa tttttgtagg ttattgtagt tttattcata ggttcttcgt
    43141 ttttcaccta tttcagcaaa ttagaatttg ttttttctaa tctatagtat tgaaagaaat
    43201 tgtaaaacat tccacaaata tattttttat attcatttca gatttaggtt aaagttagta
    43261 gttattcttt tgtgtatata agttatttga agtaataaag tttcaattga atttggataa
    43321 atatgaatat aaaagtattg aaaaaaaata aaagtttata tataatgtaa ttatactaaa
    43381 atataaacat gaaaaatata aatgtaaagg agatgtaaat atgcgcaaag aggtagtttt
    43441 taactaaact aactgaataa ggattatttt aaaaagtata tgaaaaaaat cttggataac
    43501 tcaaggttta tttgtggtag aaacaattat taataatatt gatattacca tgtctatttg
    43561 tgtactctaa aaataatcag tattataatg agcatattac atctttattt gaagaatagg
    43621 aaaactgtgt tctaaacacg gtatttttat gcctattttt actatattta tagatatgat
    43681 ataagacttt aatttgcata gcttaatcat aagttatata aattaaagtt gtatatttca
    43741 tgtttatatt taggttatat aattatgagg ctgtaagtga attatgttca cttacagctt
    43801 tttttattta aggagattat tttgatgatt tatatattta aatatgaaga ttatgaaaaa
    43861 caaataaatt tttttaaaaa tactaggatg gtgattatta atggttaata aactttcagc
    43921 atataaaact tatttattat tttcagctat tacagcaatg tgtttttcac tagtagctac
    43981 agttatgata gtgtatcaca ttgaaacggt gcatttaaat ccacttcagc ttatacttgt
    44041 tggaactact ttagaagtag catgctttat atttgaaatt cctacaggaa tagttgcaga
    44101 tgtgtacagt cgtaaactat ctattgttat tggtgtagtt ttaacaggag tgggatttat
    44161 tttagaaggt tctatttcta gtttcgtttt cgtacttgta gcacagattg tatggggatt
    44221 aggttctact tttattagtg gatctgttga agcttggatt gcggaagaag agaaagataa
    44281 agatttggat aaaatttata taaagggagc acaagcagga cagataggat cggttattgg
    44341 aatagtacta agcactgtaa tagctaattt atctgtaaga ctacctatta tagttagtgg
    44401 agtcttattt ataattcttg cattattttt atggttatat atgccagaaa ataattttaa
    44461 atcatctgct ccagaggatt taaatacttt taaaaagatg ggatatacct ttaaatctgg
    44521 tcttaaattt ataaaaaata aacctataat tataattttg ctttcagtaa ctttatttta
    44581 tggattatcc agtgaaggtt atgatagact ttctaatatg cattttttac aagatactat
    44641 gcttcctaaa cttggaaacc ttaaaccagt gacttggttc ggaatttttg gaattgcagg
    44701 aatgatattg agtgctatag taatgcattt tatggaaaag aagcttaagg atgatgataa
    44761 gaataaaaat ggaaagctgt tattatgtat aaatatattt tatatatcat ttatgttcat
    44821 atttgctatt acaaaaagat ttaacttaat gctaatagct tatttagcga caagtacctt
    44881 tagaactata aatgaaccta tatttagtgc atggcttaat ggacatatag atgacaaggc
    44941 cagatctact gtactttcta taaatggaca aataaattcc ttaggtcaaa ttttaggtgg
    45001 accaattata ggaatcatag ctacaaatat ttcagtgagt atgggtatag catgtacttc
    45061 gttattagta acaccggtat tagtgttata tattgttgct atgataatgg ataaaaaggt
    45121 ggttgataga gttggaggta ttgattatga agaaaataat taatatagga atcgtagcac
    45181 acgtggatgc aggaaaaaca actataacag aaaacttatt atattatagt ggagctataa
    45241 aatcagttgg aagagttgat ttaggcaata cacagacgga ttctatggag cttgagcgta
    45301 agagagggat taccattaaa tcatcaacca tatcttttaa ttggaataat gtcaaggtta
    45361 atattgttga tactccagga catgtggatt ttatttcgga agttgaacgt tcattaagtg
    45421 ttttagatgg agcgatacta gttatatcag gagtagaggg tattcagtca caaacaagaa
    45481 tattatttga gacattaaag gagttaaaca ttccaacaat aatttttgta aataagctag
    45541 atagaattgg ggcaaatttc aataaagtat ttgaagatat aaagaagaat atgtccaata
    45601 aagtagttag attacaagaa gtatatgatg taggaagcaa agctgtttat ataaaaaaac
    45661 tatttgatac atgcatgata aatgatgatg ctattgatgt tttatcagac ttagacgaag
    45721 catttttaga aagatatatt ggtggaatag aacctgataa agaagaaata caagaaaagc
    45781 tttcattata tgcaagtgaa ggaagtctat atccagtatt ttgtggtgcg gcagcaattg
    45841 gacttggagt tgaagactta ttagatggaa tttgtagtta ttttccattt gcaggtgatg
    45901 attgtgaaag tgatttatct ggagtagtat ttaaaatcga aagaacaagt aaaaatgaaa
    45961 agaaggttta tgtaagatta tttggaggaa aaatatctgt aagagataaa attcaagtac
    46021 ctaataagga gatagcagaa aaagtaaaga aaattaatag gttagaaaat gggggagttg
    46081 ttgaagcaca gaggatagaa gcaggggata taggtatttt atatggactt acaagtttcc
    46141 aagtgggaga tgttattgga atttcaaatg ataaaattaa aaatatatct atagctaaac
    46201 cagcattaaa aacaacaatt tctgcaattg ataaagaaaa aaatccagag ctatttaaag
    46261 cattaacatt acttgcagag gaagatccac tactagaatt agagatgaat gacatagata
    46321 aagaaattta tgtcaactta ttcggtgaag ttcaaatgga aatactaagt tccatgttag
    46381 atgatttata tggaataaaa gtagagtttt cgaatattga gactatctat aaggaaacac
    46441 ctaaaggttt tggagcgtca ataatgcata tgcaggaaga cttaaatcca ttttgggcga
    46501 cagtaggctt agaaatagaa ccagcaggga gaggcgaagg tcttaggtat atttctaatg
    46561 tttcagtagg gtcattgcca aaatcttttc aaaatgcaat tgaagaagca gttattaaga
    46621 caagtaaaca aggattattt ggatgggagg ttacagatgt aaaagtcact cttagctgtg
    46681 gtgaattttt tagtccagcc agcactccag cagattttag aaatgtgaca cctatggtat
    46741 tcatggaagc attatataaa gcacaaactg ttttattaga gccattacat gagtttgagt
    46801 taaagattcc tcaaaatgct ttaagcaaag cggtatggga tttagaaact atgagggcaa
    46861 cctttgataa tcctattgtt ataggggatg aattctcaat aaagggatta attccagtag
    46921 aaaattcaaa agaatataaa atgaaaatag cttcatatac agaaggtaga ggaatgtttg
    46981 tgacaaaatt ttatgggtat aaggaagctt cagctgaatt ttcaaaagca cgcaaaaaaa
    47041 caacgtatga tccattgaat aaaaaagagt atttgcttca taaactaaac gcaattagag
    47101 attaaattta aatagataag ttaaattttt atatgtagga tttaaatata agacattcaa
    47161 agcctaaaag taaaggaagg gtcgtctgaa gaagatgaag acccttcctt ttttcatgtt
    47221 actatgctta attgtaagtg cttgaaattt gtaatataat gtaaataaag tttttaataa
    47281 taaggggacg gcacaaatga aaatcgactt taaaataaca aaagatgact atataagctt
    47341 caatttacat catttagaaa actcgaaatc acagaaaagt acatttaaca tacttagata
    47401 tgctgtaccc ataatacttt ctataccaat ctactttaca ggaacgggga tatttaatca
    47461 accgagtata tattggatta tagtagcgat agttttttta gtcatttgga ttttaacata
    47521 tcctaagcaa tacaaaaaat tagtagctaa agaaactgat aaactcataa gttaaggaga
    47581 taattcatca atatttggaa gtaagacttt agaaattatt gatgggacaa tagtagtaaa
    47641 aggggattct atatcagaaa cagtatcgtt agaaagtata aaagatgtaa aagtttacga
    47701 agatatgatc cttatatata agtggatttg tagctcatat aattccaagg agatatttag
    47761 ataaagaaat agagaaagaa cttatgaaag agcttaaaaa atataaggct ttagaacaat
    47821 taaagtaaaa cgtgctcctt tggaggtgta acggagaacc gtatcacaag taacggagcg
    47881 cgatagcctt atcaattgat atatcttgat taaggctatt ttcatacata aaaatactgt
    47941 atcataagta atataatata attgaaaaat atcgtatagt tgtaattgat aatgattaaa
    48001 ggagagcgtt tatgggggaa agaaaagtaa atttggatgt aagtaatgaa atttacttaa
    48061 gaatgattaa agagggatat tcaccagagg atataaaaga aatggtaata gaagagttta
    48121 atcagttttt tatgaataat caagtactag aaagaaatgc aattgatgtt ttattaccag
    48181 aattaattaa cttaactaaa ttaaaacaat atgggaagta ttatcgagaa tttactatgt
    48241 gtctagatat gtataagaat agtatgaata ttgataaaga agagtgtttt aaagcatttg
    48301 ctaattggtc gtcagatatt aataaagcaa taaataaata ttggattata tataatttgg
    48361 ataaagtaag agaaaaattg actatagagg aatatgtaga ggttacattt aaaaaaattg
    48421 gcaaattaat agaagggatt ataaagcctt attcatttaa catattaaat aacatatata
    48481 taatcaaagg taaaaaggaa aaggttaata catttgaaag gaaagattta ggtacatttt
    48541 ttgaagaaat aatacagtct aatataacag gggaactttt tagaatacaa ttagacacta
    48601 taagtggaat aaaagaaata aaactaaatc aattaagaaa tatagtagca catgaaaatt
    48661 atgagattga aggagaaatc ataaattgtt ttataaagaa taagaatgaa ataaaagact
    48721 catttagaat atctatagaa caattaaaaa aatgttttgg tgatgtatat tatacattag
    48781 gagcaataaa gttagcttat acgatatttt ttgttgataa tattgatgaa ataattaagt
    48841 ataatcctga taaatcaatt ataagagtag aacagttgat taccaatacc tttttgggaa
    48901 tacaatcaca aggatttaaa atcatagatt ttgtagaaga tagtatagag agtaaactaa
    48961 tccttaaaga tgctttatgt gataatgaaa aacaaagaat gattcactca tctcaatttt
    49021 tatttagatt gtgggaaatt actaaagcta aaaacaatgt aatagaatat cttgataata
    49081 cagggaagtt gaaggctata tttcaattag attcaaatgt atgtgaacgt attaataatg
    49141 gagaattaga gccattagct caagcagaaa tgatgaaaat aaagattata taaaaagctc
    49201 atttatcatc aatatggaga acacgaaact ataatagata atattacatg ggaaaaggta
    49261 cagataatag taaaagatag aattaaaact cacaatagag tctaggatag tgagctaatt
    49321 ctaagtagac tattgaaatg tcctgtgtgt ggagcctcaa tgactgtaag taggtcaact
    49381 agaaaaataa aagatggaac tgaagcagta aatgagtact atgcatgtgg gaattggacg
    49441 aataaaggaa cggcagtgtg taactcaaac tctgtaaaag cagaagttgc agatgaagtt
    49501 gtaatcaata atctaataga aaaagtaaat aatgagatac tgctaaagag gataatagac
    49561 aacatcaata agaataagtc tagtaagcta aaaccaaaat tagatgaaac taacttagta
    49621 aataaagaaa ttgataagtt aaatggcaag aagaactcta acatagagct atttgaagat
    49681 ggaatattaa ctaagagtga attggcagag agagtaaaga aactaaatga agagatagac
    49741 acattgaaat ttagactaga tgaaataaag caagatgtga tgttagcaga aggagaacca
    49801 gcaccttttg agttagtaag tcaagtgatg aaacagtttg ggcaagtatt caaggagagt
    49861 agtacaagac aacaaagaaa gcagttgtta aacttacttg tgtcaaagat aactatagat
    49921 aaattaagag caatagatac tatagaatta caaataaatg aagatataat aagttattta
    49981 tttaaggaag gatcgtttaa agaagatcct tcctttttta gtactttcat tattaattgc
    50041 agttgtttta aatttacaat ataattaatt aagttaaaat attaaaaata cgctcctttg
    50101 gtagtgtaac ggagaaccgt atcataaata aatgatacgg tttttgttag tttgcaactt
    50161 aataatatta aaataacaaa aaagtattga aagtatattg catttaaggt agaattaaat
    50221 aaaatattat aacattataa tgtttataaa gttgttaata aaaatttgga ggaaaatata
    50281 tgataaaaat aatgttggcc tgttcagcag ggatgtctac aagtttatta gttactaaaa
    50341 tggaaagtgc agctaaagaa aatggtatag agtcgcaaat ttgggcaata ccagaatcaa
    50401 ctatacaaaa tgaaatagaa aaatgtgatg tattattact aggaccacaa gttagatatg
    50461 tattacctaa ggctcaagaa attgctaagc catataatat accagtagaa gttataaata
    50521 tgatgcacta tggaacagtt aatggagaag ctgttttaaa tagagcgata gaacttaaca
    50581 acactaagta atataaatta taatgtattt ttaatatata aattgggaga atcaaaggat
    50641 ggatgaaaag attatagaaa tatcttttaa tataataggt tatgcaggtg aaggtaaagg
    50701 gttagctttt gaagcaataa aagaggctaa gaatggaaat atagaaaaag caaaagaatt
    50761 attaaaagag tctagggaag ttataaataa agcacataga tatcaaacag aattaataca
    50821 aaacgaagct agtggaaaca ggactgaaat aagtgtcata cttatacatg cacaggacca
    50881 cttaatgaat ggcatgaatt ttcaacagtt agctgaggaa atcgttgatt tacatttgaa
    50941 attacaagat aaataaaaat taaagataat aaattaagag agttcttaaa agatacatta
    51001 tgtgtagcac actaattgtt agattattga ttcaatattt agtgagtaat acattaggat
    51061 tattttgagg actcttttta tatttagttt aaagttaata aatatttatt attaataata
    51121 taagattata tgttataata ttataacata taatttaaga ggtgaatcat gttaagaaat
    51181 caaccattat atatacaagt tgtagatata ttaaagcaaa aaatattaaa taacgaatat
    51241 aaaattgatg aaaatattcc aacagaaagg gagttagagc aagagtttgg agtcagtaaa
    51301 attactatta gaaaagctat tgagatatta gaatcagaag ggtatgtaga gaaaaaaagt
    51361 ggaaaaggga caaaagtaat aagtaatagt ctttttaata agctatcaaa agcagagtct
    51421 ttttcaagta tacttttatc taaaggtcat aagttatcta aaaagactat ttcaattgaa
    51481 aaaataataa atgatacaaa ttcacaagta tttagtatat ttggagaaaa atgtagcaag
    51541 attactagaa tgtattactt agatagtaag ccatatatat tttttactca ttatattcct
    51601 tttgatgaaa atctaactgt tgaaagtttt aataatgaaa gttctttata tatgtactta
    51661 tataggagaa atataaatat aactagattt gaagatgaat tttttataga agaatcagaa
    51721 ctagaggtat caaaggctct aaatctagct aaagacatat tattaggaag aaaaagaaag
    51781 acctatgatg agaatgataa tatagttgag ctatcatttg caagatataa tacagaagta
    51841 caaaactatg taattaaata cgaaatataa taagaatcct gagtttattg aaatgataat
    51901 atgctcagga tttttgttta gttgtaaaaa taaaaaatat tataacatta taatgtttac
    51961 aactaaacat tataatgtta taatattttt aataaacaag tgatattatc aattacataa
    52021 aaattagttt atgttatgaa atcgttattg cattataaat aaaggataat atcaataata
    52081 cagggggata actatggaaa aattcgcaag ttttttagag cgcaagatta tgcctgtagc
    52141 agcgaagata agtaatcaga gacatatgag agctgtaaga gcaggtataa tagcaacatt
    52201 accactaaca atagtggggt catttttcac aatattatta aacataccta ttgatgctta
    52261 tatggatttt atagctccat ttaaagcaat attagatata ccatttagat atactgtagg
    52321 atttttatct ctatatgcta cttttgggat agcatcatca cttgctaaaa gctacgattt
    52381 agatacaaca ggtgttggta tgcttgcagt tatggcattt ttagtttcta caatagttcc
    52441 aactcaagta gttgaaccag taggtggagt tatagaagct ggtagatgga tggatatggc
    52501 aaaacttaat tcgccatcat tatttggagc tatcgtaaca tcattaatta cagttgaaat
    52561 atatcgtttt atgaaggaaa agaatattac aattaagatg ccagcaggag ttccagtaga
    52621 ggtttcaaat tcatttactg cattattacc gacagcagta attttaatgt tattctgggt
    52681 aataagacat attttaggat ttgatataag tgttgcacta agcgctatgt tatcaccttt
    52741 aaaaggattc ttatcaggaa atagtttagg tggtgggtta ctgacagtat tcctaataac
    52801 tttattctgg gtacttggaa tacatggtcc agctataatg gggccagtaa taagacctat
    52861 atgggacatg tctatagcag aaaatataac tgcattcaca gaaggagtat cagctcatgc
    52921 aatgccaaac atatttacag aacaattttt acagtggtat gtatggatag ggggagcagg
    52981 ggctactctt gcattagttg taatgtttat gttttctaag tcacaatatc taaaaagttt
    53041 aggtagatta ggatttttac cagggttatt caacataaat gaacctataa tatttggagc
    53101 accaatagtt atgaatccaa tactagggat accatttata attggaccta taataatgac
    53161 aattctatca tatgttctta ctattacagg ggttatacct atgatggtag caagattacc
    53221 atttgcaatg ccagcaccaa tagcagcagt aatgagtact aactggagta tattagcagg
    53281 tatcttagta ttaatcaact ttgtgatatc atttgctgtt tattatccat tcttcaaagt
    53341 ttttgaaaaa caacaattac aaagagaaca agaagaaatg agtgaaaatt tataaaaata
    53401 catagatata gaggttttgt actatataaa atatagaaaa aacttataag ttattaaggg
    53461 tgaaggtagg aggaatgacc tttgccttta attttatata ttttaaataa tgtaatttga
    53521 ggaggagaaa gatggaaaga agattaggaa tatcagtata tccagagcat agtaacatgg
    53581 aagatgataa ggcatatata aaaatggctt caaaatacgg atttaaaaga atatttatgt
    53641 gcatgctttc aattacaaga cctaaggaag aagttaaaaa acattttaaa gagattataa
    53701 cctatgcaag agaattagga tttgaagtaa tccttgatat agctccaaac atatttgata
    53761 tattacaaat atcttatgat gatttaacat tttttagtga gttaaatgct agtggaataa
    53821 ggcttgacta tggatatgat ggaagtaaag aagctatgat ttctttcaat ccatatgatt
    53881 taaaagtgga actaaatatg agtaatgatg tagcatactt ggataatata attacttaca
    53941 agccaaatgt aaataatata tatggttgtc acaattttta tcctcaaagg ggtacaggct
    54001 tgccatatga tttttttgta agatgttcaa atagatttaa aaagtatgga ataagaactg
    54061 ctgcttttgt taattcaaaa tatgcaacaa tcggaccttg gaatataaat gatggactgt
    54121 gtacgcttga aatgcataga aacttagata ttgctacagc aactaagcac ttattcgcaa
    54181 caggattgat tgacgatgta attgtaggga atgcatatgc aagtgaagat gaattaaaaa
    54241 gaatgtctga agtaaataaa tatcaagttg tatttaatgt agtaactgag gaaaaaactt
    54301 ctgaagtaga aaagacaata atggcaaatg agcaacactt tagaagaggg gatataacca
    54361 accaagtagc aaggtctaca gaagtaagaa aaaaatatgc taaagaaaat ttccctaagc
    54421 atgataatac gaccatcttt aaaagaggag atgtagtgat tggtaatgat gactttggaa
    54481 agtataaagg ggaattacag ttgatacttc aagattgtgc agatgaaaga aaaaataagg
    54541 taggtagaat aaaggaagac gaaataatgc ttttagactt tattgaacct tggagtaaat
    54601 ttaaacttat tttagaggga gagtaaagtg aagatagaca tattaataaa aggtggaaaa
    54661 acagtagata aaagtataat tgatatagct atattagacg ataaaataat agaagtaaaa
    54721 aatcagatag atgattctaa gtatcaggca aatcaaatta taaacctaga tggagaaaaa
    54781 tttattagtg ctggttggat agatatacat acgcattgct acgaaagact agacctttat
    54841 aaggattatc cagatgaggt tggaataaaa agcggtgtta ctactgtagt agatgcagga
    54901 acaacaggag ctttagatat aggtaaattt tatgaagata ctaaaaaata taaaacaaat
    54961 gtatatgctt taataaatat tgctaagcag ggaataacat ctcaagatga actttcaagt
    55021 atgatgaata ttgatgaata tgaacttaaa agagcagtta aaaaatacaa agattttgtt
    55081 gttggaatca aagctagaat gagtaaaagt gttgtaattt caaatgatgt tgaaccttta
    55141 aaagtagcta aaagaataaa aaatgaactt aatctaccta tgatggttca ctttgggagt
    55201 tctcctccaa cgatagagga tatatttgac tatatggaaa aaggagatat attaacccat
    55261 atatataatg gaaagccaaa tggaatactt agaggcaatg aggttaaaaa agaaatcata
    55321 gaagctagag aaagaggtat aatccttgat gtaggtcatg gaaccgaaag ttttagtatg
    55381 gatattgcaa tgaaatctaa ggatgcagga atttttccag acactataag tacagatata
    55441 tatattaaaa atagaataaa tggtccagtg tataatctat ctacaacaat ggaaaagttt
    55501 atatatatgg gctattcact tgaagatata atagataaag ttactaaaaa tgcagcagat
    55561 gcaataagtt taaaaaataa aggtttaata aaagaaggat atgatgctga tttaactata
    55621 tttgatgtgg ttaatgaaga aaaagaactt caagattctt tgaataagtc agtaatcaca
    55681 agtacgtcta taaagccaag agcagtagta gtcaatggag aatatttaaa tataggtaag
    55741 tctataggag agaatgagta gaagggagaa actattgtat gagtagtata tttgaaaaat
    55801 actctgtaag acgtgttata aatgcttcag gcaaaatgac tatactagga gtatcaacag
    55861 tagataagga agttattgaa gcaataggtg aagggtgtaa aaatttcttt ataatagaag
    55921 aacttataaa taaaacaggt gaatatatag caaatttatt agggtgtgaa agtgcactaa
    55981 tagtttctag tgcatctgct gggattgcac agagtgtggg agcaatgata gcaaaagatg
    56041 atatgagtct agtttacaat gtaaataatc ctaagaaaca agttaaaagg gaaataataa
    56101 ttccaaaggg acataatgtt gattatggag ttccagtaga agtaatgata agacttggag
    56161 gaggagaagt tgttgaggcc ggttatgcta atatgtgtaa caaggaacat ataataagag
    56221 agataaatga aaatacagca gcaattatgt atattaaatc tcatcattgt gttcaaaaga
    56281 gtatgctaag tgtattagat gcagtacaag ttgctaaaga atataattta cctttgatag
    56341 tagatgcagc agcagaagaa gatttaaatg tatattatga attgggagca gacctagtga
    56401 tatacagtgg tgctaaggct atagagggtc ctagctcagg gttagtaata ggtaagaaaa
    56461 aatacataga taatgtaaag cttcaatcaa agggtatagg aagagctatg aaaataggaa
    56521 aagaaaatat tgtaggtcta acatgtgcaa ttgagagata tataagtaat gataaagtaa
    56581 ctttaaaaga aatggaggac aagctaaatc catttataga caagataaat actataaagg
    56641 gagtgagtgc tagtataact agggattcag caggtagaga aatacttcgt ggagaaattg
    56701 actttaatga agatataata aataagtcaa cacaacaaat tataaatgaa cttagaagtg
    56761 gagagatagc tatatacact agagactata aggctaatga aggcaagatt gagattgata
    56821 taagaagtgt aactggaagt gatttagata ctatttataa taggataaaa aatatagtag
    56881 aaagttagag tgtagagtaa gtgacattat aatgatttaa taaattgaat tttaccaatg
    56941 gaggggataa atatgaattg tataccacaa tattataaaa atagagtttg tttaaatgtt
    57001 cttgcagaaa gcataaaaaa tgctaaagaa gtatatgatg cttgtgacgg gcatgtattg
    57061 ataggagtac tatcaaagaa ttacagcact gtagaagtag ctattgaaga tatgaaaaaa
    57121 tactcaaagg aaatagataa tgcaatatct gtggggcttg gagctggaga cccaaatcag
    57181 tcaaatatgg tatctcagat ttctaaagaa cttcagccac aacatataaa tcaagtgttt
    57241 acaggtgtgg ctacgtctag agcattgctt ggtcaaaatg atagtataat aaatggatta
    57301 gtttctccaa ctggtaaacc aggatttgta aaaatatcca caggtccatt aagttcaaaa
    57361 gaaaaagatg gtatagttcc tatagaaaca gcaatagcta tgatgaaaga tatgggagga
    57421 agctcaatta agttttttcc aatgggaggg cttaaaacaa aggatgaata tatagaagtt
    57481 gcaaaagctt gtgcaaagca taatttttat ttagaaccaa caggaggtat agacttagat
    57541 aacttcaaag agatagttca aattgcactt gatgctggtg tagaaaaagt tatacctcat
    57601 gtttatacat caataattga taaagaaaca ggtgaaacga aagtggaaga tataggagta
    57661 ctttataaaa taatgaaaga attattggga tagatttatg aatatattag cttttggtga
    57721 aataatgatg agactttcag tacctgacta caagttctta acacaaacca atgaactaaa
    57781 ttatataatt acaggcacgg gattaaatat attatctgga cttaaaaact ttggatacaa
    57841 tacctatatg ttgacaaagt tgcctaataa taatgtaggt aaagcatcaa gtgcaaatat
    57901 aagaaagctt ggagtaaaag atgactttat cacgtatgga gggaatcata taggagtgta
    57961 ttttcttgaa aatgggtatg gagaaagacc ttctgaagtg acttatttga ataggttaaa
    58021 tagttcattt tgtgagagta aattacaaga ttatgatatt gataaatgtt tagaagaaat
    58081 ggatatagtc catatttgtg gtattgctat gcaacttaca gattcagtta aagagattgc
    58141 tttagaacta gctagaaaat cttatgaaaa ggggataaaa gtattctttg attttaattt
    58201 tagacaatca ttaaatccag aaaggactta tgatgattta gtaaatgatt ataagaaaat
    58261 actaccatat tgtcatgggc tgtttgctag ttatagagat ataaataaga tacttaatat
    58321 agatagtcta aatataaaat ctagttcaga attgattaaa aaagagtatg atataggtat
    58381 tgtagctgga actatgagaa gatttgatga tatgaataat agatttataa agggatatat
    58441 atcaaatgat gatggttatt ttgaaagtag ggagtataag ttagaaatat atgacagggt
    58501 tggtgtcgga gatggatatg tagtaggaat tatatattca tatttggaaa atatgaagag
    58561 tgaagatata gttgagtttg gggttgctag ttcggtgtta gctcatacaa cttatgggga
    58621 taattcttta gtaagcacag gtcatgtact tagactgatg aacaatgaaa aaatagatat
    58681 attgagataa tacatttgta tataataaaa tttttatctt ttttagacac atttttgact
    58741 tgcttatatt tgttaaacag agttattttt aacgattata aatattaaat taaaagttaa
    58801 ataataaaat agtagaaaat agcattaact atagaaaaaa tggttaatgc tatttttatc
    58861 gttaatattg attaatttta tattatagaa atgaactttt ctaatgctgg atttgtattt
    58921 tttttattcc atacaactac aacttcaatt ctattttcta cttcttttat aggtactatt
    58981 gcaatatcac gttctatcat tgtatctgta acacaaaatg aaggtaaaat ggatattccc
    59041 atgttagaag ataccaatga ttcaatagta ttaagattat ttgaacgttg taccacatta
    59101 ggtacaaacc ctgcttcacg atatctattc tgtatcattg acttttgtcc atactcatcc
    59161 cctgtttctt ttacaaaaat aaatttatca tgttgtaatt caattaaatc gatagaatcc
    59221 tcattgtaaa gtggatgacc aggaggtaaa agagctacca aagaatatct ttctacagtt
    59281 ttatattcaa aatcttttaa tggttgattt tctggattaa taacaaaagc gaggtccata
    59341 gaattatttt ttactaagtt taaaagttcg gttatctcat tagtacaaat atccatagat
    59401 atattagggt atgtattaga aaattctttt aaatattgtt gaagtttgtt tttttcgtat
    59461 cctattaagg ttccaatgct caaagttcca aaaaaaccat gtgcaaattg ttgtgttttt
    59521 gcaatagcat cattgatatt ttttattata gtacgtgcct cagataaaaa aacttttcca
    59581 gctggtgtta gttcaacatg acgtttactt cttgtaaata gagttacatt tatttgttct
    59641 tctaaagctt ttatttgctg tgtaacagca gtttgagaaa tataaaattt ttctgctgtt
    59701 tttgtaaaac ttagattttc tgctacagat ataaaatatt ctaattgttt agtattcaaa
    59761 taatcacccc tatttaaact tgattgtttg taaaccttat ttatctataa ttaaagctta
    59821 ttatagtata agaaaattta cttttaaaga atattagaaa atatttgtat aaaaatatat
    59881 gttttaagta tatctttaca ttagatttta taaatttatt aataagaata acttatatat
    59941 tccaatgaaa acgatattgg atttaagtaa gtttgtctca taaaatgaaa gtatatcaat
    60001 tgataatact ttaaataaga agggagaaaa aatggaagat aaattttatg caaaaggcaa
    60061 cggaaataac ggatatatta aaaatcttga agtttgttcc tttaataact tagatggaac
    60121 ttgtggaatg tttcaaatgg ctctgtacaa aagagatgaa aaatactatt tatatggatg
    60181 ctgttttgga ggaaataaaa aaaatggagt aatgattagc gatattacag acccttataa
    60241 tccacaattt ataaaacatt ttcaaatgtt agaccctaaa gagtatccta caacaacaac
    60301 tcccaaaatt caaatagcag atgatttaat gatagtagca atgagttgtg gaagtggacc
    60361 aggagcactt gttgaccaag ctaaattagc aaatattaag tgtgaagcag gaattagaat
    60421 atacagttta aaagaagacc ctttaaatcc taagttttta ggatattggg attgtggctt
    60481 aaagcatgta atgggtgttc atagattcat gtacaatggt ggaagatatg tacatttatc
    60541 aagtgattgt gttggctttg aaggtctgat ttatagggtc atagatataa taaatcctac
    60601 taatccagtg gaaataggta aatggtggag accagaccaa tatgcagatg gatatccaaa
    60661 tagaactttt gatgcaggag cacctcattg cccagaattt atggataaag gatggcttca
    60721 tggacctcca tttgtaagag atggaaaagc atattgtggt tatggaggag ctggtttagt
    60781 tgtattagat gttgaagatt taacaagacc aagatgctta ggtgaattgc catttatgcc
    60841 tgcattttct agtagacttg caggtgcaag aactcataca gcattaccat tgccaggaag
    60901 agatttagtc gttgttcaaa atgagggaga aagattccag ttctttaaac cagataacat
    60961 tacagatgtt caagctatga ataatataca tatggttgat gttagtgacc caacaaaacc
    61021 aacattaatt gctcaatttc catatcctga agttccaaaa gatttccctt atcctaactt
    61081 taatgttgcg ggattaggaa aaccagggcc atttggccca cataatcttc atgaaccaat
    61141 ggataataag ccatggttag agcaaagagg agatagagta tattgctgtt atttccatgc
    61201 agggctaagg gtttatgatg tatcagaccc atattatatc aaagagctag catattttat
    61261 accaccaaat ccaaataaaa caccagaaga atcttatttc ccaggattcc caggaccacg
    61321 cttggcagta acagaagatc ttatcgttga tgatagaggc tacatcatca tagatgcttt
    61381 agatgatgga ttctatatat taaaaatgaa agaagattaa ataaatacta aagagggaga
    61441 gttgaaaatg aaaatactag gtatttcttt tggaacaaaa aatggaaata atgacacaat
    61501 gtgtaaagtt gcacttaaag gtgccaaaga agcaggggct gaagtagaat ttattcaaat
    61561 gtcatctatt aacattaaac attgtactgg atgttgtgcg tgtgttaaaa ctttattatc
    61621 tgggaaaggt agtatgtgtg tattaaaaga tgattttgaa tggttgcttg acaaaatgaa
    61681 agatgcagat ggtatagtag tttcagaccc tatttttgaa gaaggggcat caggattatt
    61741 ccatactata atggaccgtt ttggacccag agcagataga ggaaataaca ttataggaac
    61801 aaaagttgca gaagctatag gaggaaaaat tccagattca agaatgctta atgataaagt
    61861 aatatcattt atgggaatag gaggttctga ctggggtaca agagttcaat gtgaacatgc
    61921 tatgctagct ctcataccaa tgtggaaagt tatagataat gcttggttcc catgggcaaa
    61981 ggaattagta atggatgata caaggcttgt tcaagttcat caaattggtt taaatatagt
    62041 tgaagcagca aaagattttg aaaaagcttc atatcaagga gaagaaggtg tatgtccaca
    62101 ttgccacaat agattattct accttgagcc aggtactaaa aaggcaattt gtgctctatg
    62161 tggtatagtt ggagagttag atactataag tggaaaaact atatttagtt ttccagaaga
    62221 gcaattaggt catgctcatg atactttacc aggtaagttt atacatggtg atgatattaa
    62281 gaaaatggaa ggtcattatg cagaagttcg taaaacacaa gaatttaaag aaagaaaaac
    62341 atcttataat tttatagagc cattaactaa agaaaagcaa gctggagttt cattaggata
    62401 ataattaaaa tactaagact cttttttaag ggatgttaga tgttatagga ggcttattgt
    62461 atgaatgaaa agccaagttt taaacaaatt gaaattattt tagcagttat ttttttggta
    62521 cttacatatt acaaggttag attaactcca gcatttattg ttatatttat accactatat
    62581 ttaagttatt ttgcagtatc tatgattgta aatcaaatag caattaagct attggagata
    62641 gggcaagcta gggaagctac taattacaat ataggaaatg gatagaaaga aaaaagaaat
    62701 attaacactg tctatgggga ttgctttact acctccttta tgggcagtat tagcacctta
    62761 tataggaata aaaactggag ctgtagcact aatctgtgca ggattatatg taactaatgg
    62821 taataaacaa aaagatggat taaaaataat gtttggtttt tggtgtggag atttatgggc
    62881 agtgttagcc attttaatta tgggatatat gaatttcaat caaaacctag aattattttt
    62941 aacacttagt atattaggtt tttttgcagt tgtaattgca tccttatttg aaaaaataat
    63001 tttcctacca tcatggcttt gtggttgggc tataggtcta actattatga caggtgaaaa
    63061 tattattaat ttacaagata tttgtattca aattgctgta gctatggcag taggagtatg
    63121 gtacgtgggt gcaggtgtag atttgtttac aatatatatt ttgagtaaag ataggaaaaa
    63181 gggaaattga aagcatgtga atatactttg attataggag aatggctatg ggttttgaat
    63241 ttaaaataat gagaagttta atatatgtag gacttgccaa ggaagaatat agacctaagc
    63301 taatggactg gttatatcgt caccatattc cagatagtat tagcactttt ggaccatatt
    63361 gtactaaata tgccttttat caagcatatc ctacaccaaa tgaaggtgag cgttttggtg
    63421 cacgtaagat gcaactaaca gaacattatt ggcttgtaga tgaacatatg cctgagatgg
    63481 caaatagaat tatgacagaa tatatgccta tggatgttct acgttggcaa gggtgtatac
    63541 cagatgtaga aaataaaagg gttcatgaaa atgcagaaag tggagatgca ggacgtgcag
    63601 taggtggaga taatggatgt ccaccattta tatttgcctt tgttccaata aactgggaag
    63661 aagactttag aggaaaagga cgtactgtac aagatggacc aaactatcgt tggcaattta
    63721 tgattaagta tccagatggt atctctaaag aagaaggaga aaaatggttc tatgatgagg
    63781 tagtgccata ctttacaaac tgttgctatg ttaatcgttt tgtcagtagt aaaataatga
    63841 ttaattatgg agcaactgct tttgaccgtg tatcagaact atggtttgaa ggggaagaag
    63901 aatggtataa agctgtggtt gaagagacaa agtcgtttat taaaaaacca gaatgggcac
    63961 aagaagagga gttcccatat ttaaaaccac aattcaatat cgcatcagta ttcttaggtg
    64021 atatagcaac tatggatgca tactcacagt atcgtggata tataccaatg agataaaaat
    64081 tatagtttgt gataagtaga ggaggcattt actcttactg gtagaagaag acttattgta
    64141 tccttaaaag taggtgaata tatagtttta tatttaaatt tatataaaac taagactaat
    64201 aaatatgaaa caatagaatt agaataattt gataatattt gttaaaagag catttagaat
    64261 gtgtttaaag attaagatat tccttttatg gtagcagata gttgaaataa taaaactgtt
    64321 atcatgaaag gaatattttt atgtatagga aatttttaaa aataaaagtt aaatatgttt
    64381 aagaacatct taaagtgaaa gaatcattgt tagaaatatg tagacaatat agtctttata
    64441 acgtatcata ttaacaagtt tacacttgga ttatgaaata aaaagagtaa ttccaaaggt
    64501 tgtaaatact atgctgactt tgatacttca aagtttaggt gattttgtaa ttggtaatag
    64561 aaatacgttt aatgagcata aagaatttat ctaataatag gagaatataa tgtatacaat
    64621 tggacaagta tctaaatttt taggaatatc tagagataca ctaaaatttt atgaggacaa
    64681 aggattagta aatcctaaga aaaatgatga aaatggatat agaatatata atcaggttga
    64741 tatctatgat attgcaacaa taaactttta tagagaaatt gatatagaaa ttaaaaagat
    64801 tcaagaaata agaaaaagta agagtataaa caatttagaa ctcttactag aagagaagga
    64861 acaaatcata ctaaaagaga tagaatataa aaagcttctc ttaaaaaagg ttcagttagt
    64921 caaagaagat tgtgacaaaa taaaaacata ttttggaaaa tacacaataa aagaaatgaa
    64981 gcctttggaa gtaaaaggta aaataaaaca tgttactaac tatgaggaat atgaagccct
    65041 aaaagagaat acaaacaact taaaaaaagc agttacatta actgatttaa gaagagtaat
    65101 aaattttaat gaagaaggta taatagaaga aaaatttata attgtaaggg aagtagatga
    65161 ctacaacaaa atcatagaag gtgaagttct atctcatccc aattgtattt atactattat
    65221 tgaagatggc agatggtcaa ctggaggaga aaatattgat aataaagtgg aagacagatt
    65281 aagagaaata gcaatagaaa atgaatgtga attacttgga atagtctatg ttaatatatt
    65341 gcttactact tatgaagaag ggattgagcg tatattttta gagatttatg cacctataaa
    65401 ataatataaa agcattgacc tgggacttac tcataggttt aaactcatga tataagcagt
    65461 tataacttat atagcaatta aatattaatt tgaaatgagg attacttatg agaacagaga
    65521 aatcattaaa aaggcctata gccagtttta ttattctaac aaatataatt tttttaccac
    65581 tttttttatt ggtagtagtg actataatgt taaaacttcc aacagtgata tctgacattg
    65641 cgttgtgtat atcagcgtgg tcatccactt ttgcatttat gatattattt aaaaaaattt
    65701 atccaggtaa gaaattttta gtacacgtaa aagatagatt tagaaataaa cttaaatttt
    65761 caacagtatc tataataatt agtatacaag tcctaatagc tgtagtagtt atatttatat
    65821 tagcatctaa aaatcatgga ataatgccta actttacagt ttcatcatgg ggagcattta
    65881 tatatttatt tttaaaaaat ttatttgcag gatcattagg tgaggaatta ggttggagag
    65941 gatttgttca aaatcatctt cagaaaagac attctccttt aaaagcatcc ataatagtag
    66001 gtttttggtg ggggatgtgg catttaccaa tatggtttac aacaggattc aaagggcttg
    66061 atttaataaa atatattata ttttttatga ttgcaattat atcaatcagt attataatga
    66121 caacttttta taatctaaat aaaactttga taatacctat tgtaatacat caactattta
    66181 attttttaat agggataatt aatggagatt taatagagct tataaattac tatgcaatgt
    66241 tatatttaat atttgcaatt gcattaatag ttataaatcc aggaaatgta ttatataaaa
    66301 atattagaga gtaatatata tctttatggt aagatataaa gaaattatta gaagaacatc
    66361 caaggaggaa taaacatggt tttactgatt gttgatgcac aaaagttaat aacaaacgag
    66421 aggttatata aatttaatga atttgtagta aatgtagaaa atttaattga tacagctaga
    66481 aaaaataata tagaagtaat atatgtacgt catgatgatg gagttgaaaa tgaattgact
    66541 aaaggtaaaa atggctttga aatatacgaa aaatttaaac catgtaatgg agaaaaaata
    66601 tttgataaaa aagtaaatag tgcttttaaa gaaactggtc tattagaata cctaacaaat
    66661 aatggtgaaa aagatattat tattgctggt ctccaaacag attattgtat tgatgccact
    66721 ataaaatgtg gatttgaaca tggatttaat ataatagttc cagcttattc aaatacaact
    66781 gttgacaatt tttttatgtc agcagaacaa tcatataaat actacaatga atttatatgg
    66841 aatgaaagat atgcgaagtg tatttcatta gaggaaacac ttagaaaaat gaaataaaaa
    66901 tagagtatga attgtatatg tacataagtt gatttcataa aaaaggatgt taaattccaa
    66961 gttaaaaatt agattaaata tattatatta tagataaggc acatcaattt tattttaaat
    67021 taatgtgctt tttaattgta gtaatttatt tataatcaat atgattttta ttatttaaat
    67081 caatttctct tgagtttctt tgtctaaaga aacttttttt atttataaaa tctacagtta
    67141 tattatagta tctattttag agaagtttaa tttttgtatc aatctaaaac aaaagttata
    67201 cttaaatgaa attgaaaacg ataaaattct caaataaaat aagtattgtg gaggtgatga
    67261 aagaatccaa tgataatatg aagactaatc ttaataagaa agtaggggtt aatggtagtg
    67321 gacaaagaaa ttgtatcaat tctccagatt ttattaaata gcacattgat tacaactaat
    67381 ggattacaag aggagtctaa ttcatcaaag agacaaatta cttatagaat aaataaaatc
    67441 aatgacatgc ttaaagtaaa aaatgtacca cttatatgtt taagagctga taaagatatt
    67501 atcgttagaa aagaaacaaa aaaagcaatt aaagaaattt tagaaaaaaa ctattctaag
    67561 aatacttatt attttagtaa gacagaaaga cttttatata tgtatttaat gctttttatt
    67621 aacatggagg atatttcaat taatcatttt ataaattcta taaaagtaag taggtctact
    67681 gtaaatcttg atttcaagga tttgatacca gagcttgaaa agaagaacat taaagttaag
    67741 aacaatcgta taaatggata ttacatagtt ggcaatgaga tggaaattag gagagtgctt
    67801 attaaaaaca ttatagaaac tttgtctaat gagaaaagtt caagagtatt tgatattttt
    67861 attaaagaat ataatttaga tagttttgaa gaggctaaaa aaattatatt aaagctaata
    67921 aaaaaatatg aaattacttt tgttgaagat agattagtag aatttatata tatatttatc
    67981 tttctaaagg caaggatgta ttcaactaga atagttactc aggaaaatgt agatattcct
    68041 aatatttcgg ttatgagttc aatgaaggag tataaatttg ctaaggaatt attagaagta
    68101 tatgggagtg aagataagat aaagcctcac aatataatgt atattagtgc ttggatttta
    68161 ggtatatcag taggaaatta tgaagaagat acagaagata aggatgtaat ttcaaaaatt
    68221 gtaaataaaa tgatgacaaa gtttggatat ttaagcggag tttactatat aagccaagaa
    68281 aaaatattta aacaattata ttctcatttt agacctgcct actatagact tttatttaaa
    68341 ttacctattt ataatccgat ttgtgaaaaa gtaaaagaag aatataaatt agtttataga
    68401 attgtaagta atgcaatgaa agagttttgc ggattatttg gagaagaaat tcaggaagaa
    68461 gagttagcat atcttacaat gcactttgca acactttttt caaataaaaa agaatttgat
    68521 ggttttagaa aaagaatagc attaatagtt tgttcaaatg gcgttggtag ttcagctatt
    68581 ttgcatgcag aacttacaaa cttatttcct gacttacact ttataccaat gtcggaatca
    68641 gttggattag aaaatataag tgaacctgta gatattgtat ttactactaa ttataacgca
    68701 gagggtttaa aaacagatgt accagtaatt aaagtaagcc ctgttatgac cacaaaagaa
    68761 aaatataaga ttacacgtga agtgtatatt caattaggtg atattttttt aagacaacct
    68821 aaaatagatg aggttatgga tataataaaa aaatatgcaa atgtaacctc tgaaagtatt
    68881 ctttcaagtg agctattagc ttattttaca cagatagaga attttacatc taaggaagga
    68941 gaggggccta tgctaagtga gattactaat gaaacactag taaaaataaa ggtaaaagct
    69001 aagaattggg aggaagctat tagacagtca gcttctgtat tagttgaaaa taacaaagta
    69061 actgaagggt atgtagatgc tatgattaac tcagcaaaag catctggacc atacatagta
    69121 attacaaaac atgttgcact tccacatgct agaccagaag ctgggtcaaa agagattgca
    69181 ataggcattg ctactttaga tagtcctatt gagtttggga ataacgaaaa cgaccctgta
    69241 aaatatgtat tttgtctaag tgcaatagac aataatagcc atttacgtgc tatgtctgag
    69301 ctagttgaac tattggaaga agatgagttt tttaaggttt tagatagtgc taaagaagct
    69361 aaagaaatta ttgattttat aaaaacacac gaattataaa ggaggattta attatgtata
    69421 aaattttaat cgcatgtaga gcaggagttg gctcaagttt aatgttaaaa ataaagactc
    69481 aacaaattat taaggaaaat aactttccaa ttgaagtaga gcatggttca ttggattcac
    69541 taaatggatt caatggagat gctgtagaaa cattaattga tgttgctgaa gaattaaaaa
    69601 ataaaaattt gaagtttgat ataattggga ttcacaatat tgttgaccgt aatgaaataa
    69661 agacagcact agaaaaattc cttgcttcaa aagagggata aatttaagat gataaggagg
    69721 aatatttatg gagtttatta ttagtttgct gagtacacct gctgttttgc ttggcgtagt
    69781 tgcatgtata ggattgattc ttcaaaagaa atcagctgtt gaagtattta caggctcttc
    69841 aaaaacactt atcggttttt tgatatttgg tattggtgcc tctgctatga caggagcact
    69901 tcaaaatttc aataaactgt tccaacatgg ctttggaatt actggtgtta tagcttcacc
    69961 agaagcagct acagcacttg cacaaggtac atatggtttt gcagtttcat gtacattaat
    70021 tcttggattc atattaaatt tagtatttgc acgtattaca aagtttaaga atattttctt
    70081 tacaacaggt catagtttgt tcttttcttg tgtattagtt ttaattatga aagcacatgg
    70141 atttgataat acaatcacta ttttaatagg aggaactatc ttagggttta tgtctgctgc
    70201 actacctcaa ttctgtcaac catttatgcg tgaattaaca ggtggcgacg aacaagctat
    70261 tggtcacttt aacatgattg gttatggttt atcaggttat attgggcgtt tattttcaaa
    70321 acataaagat gatacaacag agactataga atttcctaag tggttatcaa tattcagaga
    70381 cttcttaatg ggtctatcca tagttatgtt aatcttattt tatattgcaa cattaaaagc
    70441 tggtcaagca tttactcaag aaattgctgg ttcaacacat tggttggttt ttccgcttat
    70501 agaggcattt acatttgtgg caggtatgtc aatattgatg tcaggtgttc gtatgttctt
    70561 agctgaaata actgcagcat ttgtaatcat ttcagaaaag tatattccag gttcacgtcc
    70621 tgcgctagat gttccaacag tatttccata tgcaccaaat gcagttatta ttgggtttat
    70681 atcagcatat gctgctggtc tattagcaat tgctattatg gcatcatttc ctagtatatt
    70741 tcctgtagta attattccag ctgctcacat atgttttttc tcaggaggta cagctgcaat
    70801 atttggcaat acttcaggag gatggagagg ggctattgct gggtcatttg ttgtggggtt
    70861 attacttgca tttttaccag ttatactata tccagtttat gggactcttg gtatagaagg
    70921 agcaactttc cctaatattg attacaatgt agttggttcg atattacata atattttaca
    70981 atttataaaa cctatttaaa ctaaattata taaaagtata gtcatagtta ctatgatttc
    71041 aaggaggata catcttatgg aaaatacatt atctgaattt ttagataata tatctaatga
    71101 attgtcagaa tttattgcct caatagatga gacatctata aataaagcat gcgaattaat
    71161 tcttgaagct gaaaaaaatc acggacgtgt acatgtgact ggtattggca aaccaggaca
    71221 tgtatcggga tatatttcat cattgctttc atctactgga acgtcagcat atatattgca
    71281 tggtacagaa gcagtacatg ggtcaagtgg tcaagtagtt gaaggagatg ttgttattgc
    71341 aatatcaaat agtggtgaaa ctcaagagtt aaaagcaact cttaagattc taaaagtaaa
    71401 tggagcaaag ataattggtg taagtggtaa tgagagttca tttttaaaaa atatttctga
    71461 tatattcctg tttgcaggtg ttaagcagga aggagattgt cttaataaag ctcctcgtgc
    71521 ttcaatttta gctgaaacaa taatattaca atcattaagt gttgtattac aatatgctaa
    71581 aggtcttaat acacagcagt atttgaagtg gcatccagca ggaagtcttg gaaagtctat
    71641 tagagaggga atataatttt atgaaatata aagggattat atgtgcaatg ataacaccat
    71701 ttgatgaaaa tcaaaatatt aattcacaag caacatgtca attaattgat tatttgattg
    71761 aaaagggaat ttatggatta tttattttgg gcactaatgg tgaatgtcat gtattaacag
    71821 atgatgaaaa agttgaattt gcaaagattg ttattaatca tacaaataat cgtgtacctg
    71881 tttttgttgg aacagggggt aattcaactc gtgaagttgt agatttatct aagagaatgg
    71941 aagcgattgg agcaagtgca ttatctatta ttacaccata ctttgttaca ccaacacaac
    72001 aggaattaat cttacattac aaaactattg ctaattcagt taatttacct attataatgt
    72061 acaatatgcc aggtaagact ggaattaata ttgaaccaga gtcagtacgt gaattatcaa
    72121 agataaagaa tattgttgga attaaggata gtagtggtaa acttgacaac atgaaagctt
    72181 atattgaagc aacgaagaat gagaatttta gtgtgttttc aggctcagat tcacttattc
    72241 tggatagtct aaaagctggt agtcaaggag ctgttgcagc aacaacaaac ttcctcacag
    72301 agattggtat ctctatctat gaaaacttta tgaaagggga tttggaagaa gctcaaaaag
    72361 ctcaaagtag tatagaagaa cttcgacgta tactgaaact tggaacaatt ccatctgtta
    72421 tgaagaaaac tattgtcttg aatggaatta atgttggaac tgcacgactt cctgtaactg
    72481 aaccaactgg ggaagtactt gaagaaatta aacgagtagt tgaaaattat aggacaatac
    72541 ttaataaaag tagtgagaat agataatata aatagggaaa ttacactggt atataattaa
    72601 tatatatatt ataaaacatg actaaaatta atgaataagt aaagtggttt gatgagtata
    72661 gaggtgataa tatgaaaaag atgaatataa ccaaaagaat gtcagaatgt ggggctcttg
    72721 caattgtaag agaagaaaat cttaaccgtg catgtgaaat tgctgaagga tgtataaaag
    72781 gtggtataac agttatagaa atgagttata ccctaaataa tgctggagaa ataattcaag
    72841 ggcttaataa aaagtatggt gaaacacttt gtgtgggagc aggaacagtt ttggatagtg
    72901 aaacagctcg tcatgctata ttacatggag ctcaatttat tattgcacca aattacaatg
    72961 aaggtgtagc gaagatttgc aatagatatc agattcctta tgctccagga tgtacatcat
    73021 tgactgaggc agtagatgca ctaagtttag gagcaacttt tataaaagct ttcccaatat
    73081 cagatttcta tggacctaaa ctagtaaagg tatttaagac accaatacct gatatgccag
    73141 ttttagcaag tggagggatt aatattgaaa acctacatat atggttagaa aatggagttg
    73201 atgtatgtgg atttggtggt ttattaacta aaggttctgt tgaagatatt gctaaaaatg
    73261 ctaacaagat tcgtgaaatc attaaaaata taagaaaaat ttaacatagg gctgtatcat
    73321 agtatcttat aattactatg atacagcctt tttaatatta ttcaaattta aaacagttta
    73381 catttatatt atattaaata taatttcagt aattttatat taatttttct atctggaaaa
    73441 aaatgattta aaacttaagt tatgatataa tttcattaaa agaaggcgat ttttagtaaa
    73501 tatgagaaaa taatgtgttt ttaggggaaa agttaaatac agatttaagt gaacaagaat
    73561 cgataattaa gatattaaat ggtgaatagg gcatcaaaaa aattactaaa ttaaaagttt
    73621 tagagggaga atcttagcaa gtgtgtgtga aaattcaatt tcaaacaaaa aataattgta
    73681 aatgaaatca atttatacac gttgaagatt cacttttatc attatattaa aaagcagagt
    73741 gaattaaaag tgagtctaaa gataggagga taattaaaac aatgaaagaa gacattaggt
    73801 tacatcgaat gtgtaaaaaa gaacaagcaa caaagaatga agttatatca gaggatattc
    73861 taaaatctat gagtattggg gtcagtaaac attttttaga tgattcattt acaataatat
    73921 ggggaaatac atcattctat caattattag gatatacaga agaagaattt ttagttaaat
    73981 tttctagttt aaaagattat tatgaacaga atctttatca ttttgaatct atgaaaaatc
    74041 attttttaga ggcttatcat catggcgaaa agagtataga atatcaaatt tgcatttcag
    74101 caaataatgg agaccctgtt tgggtaataa tgactggtat attaattgaa tcacaagata
    74161 atgagaaatc aatggtctat atattgtatt caaaaattaa tgagttaaaa ataaagcaag
    74221 aagaactatc tgatatggaa aaagagagta cagagaattt taaatggatg atgtcagagt
    74281 atgctgggaa tgtttatatt agcgatatgg atacatatga attactatac ttaaataagc
    74341 actcatgcaa tactttacag gcatcagcaa atgaacttat tggaagaaaa tgttatgagg
    74401 taattcaagg tagaacttcg ccatgtccgt tttgtacaaa ttcgtattta aaaaaagatg
    74461 acatatatga atgggaattt tataataaaa aactgaaacg aacatttata attaaagacc
    74521 gtatgttgaa ttggcaaggg cgaagagttc gtattgaatt atcttatgat atgtatagtg
    74581 ctgaatataa attagcaaaa aaagatcagg aaagagaatc aattttgaaa actattccag
    74641 caggaatggt tagattagat gcaagagatt atcttactat actttggtgt aatgatatat
    74701 ttttgaatat gattgaatat acaaaggaac agtttgcaga ggaacttaat aatcaatgtg
    74761 gatatttatt ttctgaagat tataaacgta gtaagaaact ggcacaagat ttgaaggagt
    74821 ctggggataa tgttgtattt gaagcaaaaa tatatacacg ttcaagggaa gaacgtatat
    74881 ggactgttac attgtgttat atcagtgggg aagacagttg ggatggaata ccatcttttt
    74941 atagtatagg tattgacata acaaaggaaa gaaaacagat tgagaaatta cagcatatat
    75001 cagagaaaga tgcattaaca ggaatttata atcgtgctga gactgaaagg cagattaaga
    75061 aatattttga aaaaaattta aatgttatgg gtgcactgtt tatgattgat acagataatt
    75121 ttaaacagat taatgataca gaagggcata tgattggaga tatagtactt actgagatgg
    75181 catcaggtat gaaaaaaata atgcgtgaca gtgatgttgt tggaagaata ggtggagatg
    75241 agtttacaat ttttatgaag aatatttctt cagttaaaga tgcagaaaag aaagcagaag
    75301 aactattgta tatgttccgt catctatttc agaaagaaaa aagttttcta aaagtaactt
    75361 gcagcatagg aatagctata tatccaaagg atggtactac attcaaggaa atatatgcaa
    75421 gagctgataa agcactatat caagcaaaaa atatgggaaa aaataattat gtaatctaca
    75481 accaagatta ttttaaagaa ttagaagaat ttgattgttc ttctcttggt acagttattg
    75541 attcagaaaa acaatatgct gaatgtcctg ataatcttac acgttatata ttccgtatgc
    75601 tttatcagac tgatgatata gaccaggcga ttaatatgat acttgaggtt gttgggaaac
    75661 agtttgatgt aagtcgtgtt tatatttttg aaaatacaga agatggtcga tatacttcta
    75721 atacttatga atggtgtaat gaaggaatct cttctcaaat ggcttatttg caaaaccgca
    75781 attatcaaga ctatgaggat tatgaaaagt tttttgagga tgaatcagtt ttttattgtc
    75841 gagatatcca cacattaagt cctaaactag aagaattgtt ttctagtcaa ggtatccact
    75901 ctacacttca atgtgcatat aaagaagata gagttttcag tggatttgtt ggatttgatg
    75961 aatgcacagg actacgtcta tggtcacaag aggaaataag tacattatca ttgatttctc
    76021 aaattatatc aatgttttta caacgtaaaa aaaataataa acttaatcaa cagattcaac
    76081 aataccagaa tattttagat aatattgacc agtgtatttg tgtgattaat aaagaaaata
    76141 attttttatt atatgtaaat aaaaaattta aaaatacata ttctaaattc caaattggac
    76201 aaccttatta tcttgattct atagatattc ataagatatc cattatatgg aataaaaaag
    76261 aagcatacct atgtactagc atgatttaat ggtaaagtaa agtttatatt ggacttaaat
    76321 taaatttcgt tttaaataag atattatttt agttgattac tgaaaagact agaatctata
    76381 ttaatgaatt atactaattt tataccacta ttaaaatatt gtttgctaaa aataaaaaat
    76441 agccttaaaa cagttgatta taaaaaatta actgctttaa ggctattttt atctttgtga
    76501 cgaaatagac acttgccatt tagaatgtga caatatagta gttgtttaga aaaggcacaa
    76561 agcattatac tttaactaaa gtaaaatgta ttttgctttt agaataaaaa caattaggag
    76621 ggagctataa ttgaaaaaga taatatatgt attatttaca attgaactat taatagtatc
    76681 tttattaggt ctaaatatag ttaaagataa tgaaattaat aatattttat ataacgatac
    76741 aacaagtata tctgtaatgt ttaaagatta taaaaagtta aataaaaatt atagtaagtg
    76801 gattaaagat attgcagatg aaaataatgt gactatatca aagtatgttt ttaataataa
    76861 tgaaaaatta tctatatata cgactgatac aagtttgaat aacaatataa agttaaaatc
    76921 aggaaaattt cctaatacta attcaaatga atttattagt aatataaaca ctaataatag
    76981 taatcaagta ggtaaattct caactatgag taaagacata tcaattttaa ttagggattt
    77041 tggtaaaata agtgaagttg gagaatcagg aatcttatat atttcaactc aaaatgaaga
    77101 tacaataaat aaaatattaa gagaactaaa tgtagataga agtatttttg tagcaagatt
    77161 acatgataga tatgttaact caaatttata cttaaatcct tcaataatta gagatttaat
    77221 actaattatc ctttgtttct tggctacaat aatacattat tcaattagtg tgagtagaga
    77281 ggcttctatt ttaagattaa atggatactc taagctagat ataattgcta gagttataaa
    77341 aaatatactt agaattatga ttttatcatc tgtcacagca ttattaatat atataatcta
    77401 tattttaaaa ttaaatatag gtgttagagc atgcttatac tttgctatgt tttcgattat
    77461 atgtattttg ataaatattt tgatatctat attaatagtt ggttttaata gtagaagttc
    77521 taaatatgtg ctatctctaa atggaaaaaa atcttatggt tttgtaaata taatgcattt
    77581 cacattgaaa attgtatttg tatcatttct tatattatcc ataaataact gtattttaaa
    77641 ttataatatg ctacaaactc agttaggaaa tctatctgag tgggataaag caaaaaatgt
    77701 ttataatctt actcttaaag atacaggcga acaatcttta ggaaaggaag aagtaattaa
    77761 aaatgccaag attaaaggtt tctataaaaa tttggtagaa gaaaaagatg ctttcttaat
    77821 agattcaact aattttgaaa aacttgaaga tggaagttac atgtatgaaa taaattcaaa
    77881 gggtaaaaac ccagaagtaa gtcaatatgg taaaaatata aaaataaata aaaactatct
    77941 taaagttaac cctatttact caaatggcaa agaaatattt aatctaatcg attatgacga
    78001 taagactata aatttattag ttcctaaaaa gttacaagta catgaaaatg agattaaaaa
    78061 agagtttaga gaattatttt attttgaaaa aatagaagta gaaaatatgt acaataaaga
    78121 gttaaataga gagttaaata aaacaaagaa gtcagattta aatgttaata taatatatgt
    78181 agataataat caaagctatt ttacttataa ctcccttgtt atggatgaca ataggaatct
    78241 cattgatgac ccaatagcaa tagttgacat agataatatt gatgattctt tttatctttc
    78301 ttatatatct agatgtgtat attttaattc taagaaatta gatgcccttg cagatataag
    78361 tagcattatt gaagctcaag gtgtagaagc gcatatccaa agtttacatg ctgtttataa
    78421 tgagtatggt ttagaaataa ataaactaga aaaatatttg aatagtgaaa tttttactat
    78481 aataataata gcaatatcaa acttaatgat tacctacaat atagtagcta gctactatga
    78541 aagaaataaa tataagttat atattaaaaa aatatttggt tattcaacta cagctagaag
    78601 tatgttgtta atagtctcat taatattaac aaacattatt ccaataggca ttatatcaac
    78661 aagagtagat ttaagtaata atattatctt atttggactt ttgatattag ttatagaagt
    78721 aattgtatct attgtattag acaagattat ctcaaatagt tcatttaata aaattataaa
    78781 aggagaacat taaaaagatg atttcattaa taaatatatc taaaaaattt aaagataaat
    78841 ctataataga caaatttaac ctagaaattt ctaagggcga gtttgtagcg ataacaggaa
    78901 atagtggttc aggtaagaca actttactta atataatggg attattagaa aaacctaatt
    78961 ctggtgatat tataataaat aatataaaaa atccaaatag taaacagata agaattttac
    79021 aaagggattt ttatggctat ctatttcaaa attatgcttt aattgagaat gaaaatgttg
    79081 aaaataactt gaaaattgct ttaaagtatc aaaaaaatat caaccataat gaaaaaataa
    79141 attacgcact tgagtctgta ggtcttagaa aatacaataa aaaaaagata tacgaattga
    79201 gtggaggaga acaacaaagg gtagcattag caagagtaat attaaaagaa tgtgaagtaa
    79261 tatttgcaga tgaacctaca ggtaatttag ataaaaaaaa tagagacata gtatttgata
    79321 tacttaaaag cctaaataag aatggtaaaa ctatcgtatt tgtaactcat gatttagagt
    79381 tatcggagca ggcagataga gttataaaat tgtaataata tcaactataa taaatataag
    79441 aaagagatta cagctaaatc aagtttaata ataatacgaa tagaatttaa acattaagta
    79501 aattagtagt ttgtaaatat aagtataata tgatatcata aaggctcaaa agaaatttta
    79561 tataataaga aatctaaaaa taacaaatgg aggacatata aagatggaaa atttaccaaa
    79621 ttgcccgaaa tgtaattcag aatatactta tgaagatgga actcttttag tttgtccaga
    79681 atgctctcat gagtgggcat taggattggg agctgaagaa gattcaaata ttatcaaaga
    79741 tgtaaatgga aatgtattaa atgatggaga ttctgttaca gtaattagag accttaaagt
    79801 aaaaggaagt tcatcatcta taaagattgg aacaaaagtg aaaaatatcc gtttaatcca
    79861 tgactcatca gatggacatg atatagaatg taagatagat ggttttggag ctatgaagct
    79921 aaagtcttct gttgttaaaa aagcgtaata ttataaataa gctgtagtgt ttattgtttt
    79981 tcagtacagt ataaaaccat aagaatctat taagtaataa aagtttgttt atttgtcttt
    80041 atattttctt atggttttat taaatataaa ttttattgaa caccaaaata ttctctcctc
    80101 tacaaataag ccaatcttat ttaaactaat atactttgta ctatttatac tgaaattgta
    80161 aatttaaatg ctatgttatt taggtttgta tagttaattt atatatttct gattttataa
    80221 attgtattta ttattatatc ttgattctaa aatcattaaa aatttcaact tctataaaga
    80281 tttacaattt atcaaataca ttatgagtat ataaacaatt tattattaca gtgctacatt
    80341 taaaataagt cttagtataa aggtattgtt acaagtataa agaaacttat gtatgctatt
    80401 ggaataaata ataccttaaa ttataattaa gaataagaac tgttaaataa gggacttgat
    80461 tatcatttag ttatagataa tataatatta aaaataaagt ttaagaggag aaaaaatatg
    80521 atagatatac ataaaaatat atatgataat aagttatttg aggagctaaa gattgactgt
    80581 aagaagtgct ttggactttg ctgtgtagct ctttattttt ctgcttcaga tggatttcct
    80641 atcgataagg aatcaggaaa accttgtatt aatttacaac cagattttaa atgttctgta
    80701 cataatagtc ttatgaagcg aggttttaaa gggtgtactg catatgattg ttttggttca
    80761 ggtcaaaaag tagcacaagt aacatataag gggatagact ggatgcaatc accagaacta
    80821 acaaatcaaa tgtctgaagt gtttttaatt atgagacaat tacatgaaat gttatggtat
    80881 cttaaagaag catctgtatt aaatatatca gatacaatca aatcaaaaat tgatttaata
    80941 attgaagaaa ctgaaaagat aactaatatg ggcccagaac agataattaa tttggatatc
    81001 atatcacata gaacaaaggt taatttatta ttatcacaag cgagtgagtc tgtgatggga
    81061 aaggttaaat catttatcaa gacttctact cttaaaaaca tgaaaaaatt aagtaaaaat
    81121 atagatttaa taggagcaga ccttagaaaa ataaatctaa taggagcaga tttaagaggt
    81181 agatttctaa tagcagcaaa tttaagaaat acagatttga gtggggcaaa tttaatagga
    81241 gcagacttaa gagattgtga tattagaggt gctaatcttg aaaatagtat atttttaaca
    81301 caattacaag taaatactgc aaaaggagat tctagtacga agttaccagc ttcactaata
    81361 cgccctaaat actgggaaaa ataattaaat taatacataa ttttacaaaa tataaacttt
    81421 tttgacttta gttcatatta tacattagag attctttaca agaatttctt aatataatat
    81481 agggagagat ataaaaatga gttatcaaaa ttataaatgt gaaagagatt atgtgtatga
    81541 tgattataaa tacaataagt gcaacaagtg ctataatgat tatgaggaaa tgacacatgt
    81601 tcatgaatat tcagaaagtg ttaagttagc agaagaatgt gaggatagac ataaccaccg
    81661 tgcagcaggg gttactggtg aagctatacc aataaatgta ggtacaaatc atgttcataa
    81721 aataaatgat aatgtagatt tccttgacca tttccataag atatgtgtta caacagggcc
    81781 agcaattaga atacctggaa ctgataaaca cattcactta atatgtggag aaactactgt
    81841 taatgatggt cattgtcata aattcctttt tactactcaa atagaagcac ctttagtata
    81901 agctgatgtg aattattgta gtgaatttgc tagattatag tataatatat aatagataat
    81961 atttaaactt aatgaggact atgatattta accttcgtag tcctttctaa gttttgtata
    82021 aaaaagtgtt atgcaattaa aagtgatata gggaggaaat ttttatgaaa tctggaataa
    82081 ttcttgaaat gaaacaaata aattcaatag aatatgacga aatgttgcaa gtctgggaat
    82141 catcagtaag agcaacgcat gattttttaa cagaaaaaga tattgaatct ttgataccat
    82201 tagttgagat tggacttaaa gaagtagaaa atatagtttg tataaaagat aatgatataa
    82261 taaagggctt tataggaata gataaagata aaattgagat gctctttata gaagataaat
    82321 atagaggaaa tggtattggt aaaaaattaa taaaatatgc tatagataaa tacaatgtaa
    82381 aatatgttga tgtaaatgag cagaataaaa aagctgtagg attttatatt cacttaggat
    82441 ttaaagtgtt tgataggtct gaaatagatg gacaaggtaa cccatttcca atactacata
    82501 tgaaattaat ttaaagttat aattctcact tattcgcaaa aatatttact taaattttta
    82561 tacaaataaa agtcgtgaca gtcttaggac acgacttttt tactacacta ttaaattgaa
    82621 atttatctgt tctatattat gattattaga tgtagttttt ttattttaac tatgtactta
    82681 aataccaagt atacccatac ctatcaagta cttcagcagc gccatcattt tgatgtggtg
    82741 gtgggtgtgg taaaaattct tgtacaagtg taccaccttc ggcaagtttt acagatattt
    82801 cttctatcgc ttctcgagat ggtagaacaa cacaaatcgc catgccagaa attacaacag
    82861 gcttgtctgt atccgctccc attatacaac cttcgtattt tgtgaaagta acacttgcgt
    82921 gcataatagg attgtttgga ttgctgtcta atcgcgcaaa tatagttttt cctcctccga
    82981 aagcctcagc ataaaaatta aatgcttttt cacaagtacc attaaatatt aaatatggag
    83041 ttagcatgac caatatatcc tccttgatat agaataattt atagttgcac ctgataatct
    83101 aaattatgat ttagtaaatt gtatcatagg gaaaccttga agtatataat tttttattat
    83161 tatattatac aaatttatta atttaaaaaa atgttatatg tacggaaggt ttacaggata
    83221 aaatataata aaaagattaa ggtgacatta taaaaaatgt atattgacat tgacgctacg
    83281 taattgtata tactttgtct taaaggagat ggtaaatatg aatattatag aaattcgctc
    83341 agataaaata tacaagaaga taatggatgc gccaataaac aaaaaagaag atatatacag
    83401 atatgaatta atgaagcctt ttgaatttaa gtggaagtgt atgaatgttc caatagttgc
    83461 tagacagaaa ggtggatatg atgtaattat agcaagtgaa atgttagggg ttttatcgcc
    83521 taaggatatt gatgaaaagc aaaaaaagaa tataaatgtg ttatctgctg ataaaatttg
    83581 gggcacttgc aaagaaacca tagaaaactc tataaatgct tttataaaag aagggtatga
    83641 tttaaacatt aaggactata aatattcaat attattggcg aatccaaata gtccttatac
    83701 aatattaagt gatggatact ggggtgatgg tgggattcct ggatatatat ttctatcatt
    83761 ggttcctaat gaatatacta tcaatagatt accagtatta atagcacatg aatgtaatca
    83821 caatattaga tttcagttta tagagtggaa taataatata acattagaag aaatgatgat
    83881 aaatgaaggt cttgcagaaa attttgcaac atggatgttt ggagaggaaa tgttaggacc
    83941 ttgggtcagt agaacagata tcgaaacatt aaatacttat ataaagccaa taataaaaag
    84001 tgctttaaaa gaaactggat ttcaaaatat aacatcttat ctttatggtg atgatatagc
    84061 taaaatgcaa ggatattttc cagtagggtt gccttattgt gcaggatatg cttgtggata
    84121 ttatatgatt aagtattatt tagaaaagac aaataaatca ataatcgaag cgactttatt
    84181 gccttatagt gagataatcg aagcagtaaa agagttttgg gaataaattt tataaattgc
    84241 ataatttgaa ataaattatg caattatttt atttttaaga aaaaataaat tgacaataat
    84301 ttataagaaa tatacaataa tatatataaa gaaatatttc aatatttaaa agttttaaga
    84361 tttcatatct agagtagcta acattacatg ttagtttctt gttacttatc taattacttt
    84421 atatttcgta gttatacata aaattactat aa
//
LOCUS       DAEQAF010000005        83109 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.005, whole genome shotgun sequence.
ACCESSION   DAEQAF010000005 DAEQAF010000000
VERSION     DAEQAF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 83109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83109
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.005"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            505..1572
                     /locus_tag="KRN00_000444"
     CDS             505..1572
                     /locus_tag="KRN00_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1826333.1"
                     /translation="MKFKKLVSLGILSTLLLSVITGCSNVSSGSNLKSNNKTKGELTV
                     YTAIEEDSIDTYLATFKEKYPDIKLNVLRLSVGGITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNSAFKDDKKVPSWVGIDAWMTGITVNTKELKAKNISA
                     PSSYEDLIKPEYKDLISMPSPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            1764..2294
                     /gene="rnmV"
                     /locus_tag="KRN00_000445"
     CDS             1764..2294
                     /gene="rnmV"
                     /locus_tag="KRN00_000445"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBH1826334.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            2465..3334
                     /gene="rsmA"
                     /locus_tag="KRN00_000446"
     CDS             2465..3334
                     /gene="rsmA"
                     /locus_tag="KRN00_000446"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBH1826335.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEVGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREVLKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            3400..4674
                     /locus_tag="KRN00_000447"
     CDS             3400..4674
                     /locus_tag="KRN00_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826336.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEEYEELEEEDEEIEENEESDRDED
                     SEEEYIIEEYDEDEYEDYWEDDEDIEEGELKARTEVEDSDDEEIEEFNNYKEIENYNR
                     VKVQEEYIDIEYDEEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANG
                     VSQGESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTM
                     PYLGYLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGS
                     TGFLRYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            4825..5940
                     /locus_tag="KRN00_000448"
     CDS             4825..5940
                     /locus_tag="KRN00_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1826337.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKILGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            6126..7022
                     /locus_tag="KRN00_000449"
     CDS             6126..7022
                     /locus_tag="KRN00_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1826338.1"
                     /translation="METRYEEANKITIQSILWNVVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            7092..7889
                     /locus_tag="KRN00_000450"
     CDS             7092..7889
                     /locus_tag="KRN00_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826339.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(7945..9297)
                     /locus_tag="KRN00_000451"
     CDS             complement(7945..9297)
                     /locus_tag="KRN00_000451"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBH1826340.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            9516..10394
                     /gene="purR"
                     /locus_tag="KRN00_000452"
     CDS             9516..10394
                     /gene="purR"
                     /locus_tag="KRN00_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBH1826341.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            10550..10828
                     /gene="spoVG"
                     /locus_tag="KRN00_000453"
     CDS             10550..10828
                     /gene="spoVG"
                     /locus_tag="KRN00_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBH1826342.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            11041..12420
                     /gene="glmU"
                     /locus_tag="KRN00_000454"
     CDS             11041..12420
                     /gene="glmU"
                     /locus_tag="KRN00_000454"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBH1826343.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEAEVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            12515..13465
                     /locus_tag="KRN00_000455"
     CDS             12515..13465
                     /locus_tag="KRN00_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBH1826344.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      14309..14394
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            14556..15077
                     /locus_tag="KRN00_000456"
     CDS             14556..15077
                     /locus_tag="KRN00_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1826345.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTPDGQTGLSVLETYMESLPDKADIGGEYKLIKVG
                     SKLVLQIGTNTEGVTLTEAQSAKLLSDIGEKKIYTSATTNSLGDPLTSNTKIDNKVLY
                     IVLIDNTVMDTTK"
     gene            15229..16905
                     /locus_tag="KRN00_000457"
     CDS             15229..16905
                     /locus_tag="KRN00_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH1826346.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            16917..18125
                     /locus_tag="KRN00_000458"
     CDS             16917..18125
                     /locus_tag="KRN00_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH1826347.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            18140..19852
                     /locus_tag="KRN00_000459"
     CDS             18140..19852
                     /locus_tag="KRN00_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBH1826348.1"
                     /translation="MNKVYVSYYGDYISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            19845..20753
                     /gene="pilO"
                     /locus_tag="KRN00_000460"
     CDS             19845..20753
                     /gene="pilO"
                     /locus_tag="KRN00_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBH1826349.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEIIKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            20780..21346
                     /locus_tag="KRN00_000461"
     CDS             20780..21346
                     /locus_tag="KRN00_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1826350.1"
                     /translation="MSLYKNNKKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            21383..21910
                     /locus_tag="KRN00_000462"
     CDS             21383..21910
                     /locus_tag="KRN00_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1826351.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            21931..23469
                     /locus_tag="KRN00_000463"
     CDS             21931..23469
                     /locus_tag="KRN00_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826352.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRNISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYSWNSKWDTLENLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKNGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            23565..24647
                     /locus_tag="KRN00_000464"
     CDS             23565..24647
                     /locus_tag="KRN00_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBH1826353.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKSGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            24628..25410
                     /locus_tag="KRN00_000465"
     CDS             24628..25410
                     /locus_tag="KRN00_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH1826354.1"
                     /translation="MDIIIVNLYVFIVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGILFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGLYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            25512..26162
                     /locus_tag="KRN00_000466"
     CDS             25512..26162
                     /locus_tag="KRN00_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBH1826355.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            26176..26736
                     /locus_tag="KRN00_000467"
     CDS             26176..26736
                     /locus_tag="KRN00_000467"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBH1826356.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            26753..30139
                     /gene="mfd"
                     /locus_tag="KRN00_000468"
     CDS             26753..30139
                     /gene="mfd"
                     /locus_tag="KRN00_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBH1826357.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            30170..31165
                     /locus_tag="KRN00_000469"
     CDS             30170..31165
                     /locus_tag="KRN00_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1826358.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFEDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            31289..31828
                     /gene="spoVT"
                     /locus_tag="KRN00_000470"
     CDS             31289..31828
                     /gene="spoVT"
                     /locus_tag="KRN00_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBH1826359.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            31948..33561
                     /locus_tag="KRN00_000471"
     CDS             31948..33561
                     /locus_tag="KRN00_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1826360.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            33668..35116
                     /gene="mazG"
                     /locus_tag="KRN00_000472"
     CDS             33668..35116
                     /gene="mazG"
                     /locus_tag="KRN00_000472"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBH1826361.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEESFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            35205..35483
                     /locus_tag="KRN00_000473"
     CDS             35205..35483
                     /locus_tag="KRN00_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBH1826362.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            35555..35797
                     /locus_tag="KRN00_000474"
     CDS             35555..35797
                     /locus_tag="KRN00_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBH1826363.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            35859..36113
                     /locus_tag="KRN00_000475"
     CDS             35859..36113
                     /locus_tag="KRN00_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBH1826364.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            36114..36647
                     /locus_tag="KRN00_000476"
     CDS             36114..36647
                     /locus_tag="KRN00_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826365.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIICF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            36653..36937
                     /locus_tag="KRN00_000477"
     CDS             36653..36937
                     /locus_tag="KRN00_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBH1826366.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            37050..37970
                     /locus_tag="KRN00_000478"
     CDS             37050..37970
                     /locus_tag="KRN00_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBH1826367.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIKFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYDEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            38060..40432
                     /gene="spoIIE"
                     /locus_tag="KRN00_000479"
     CDS             38060..40432
                     /gene="spoIIE"
                     /locus_tag="KRN00_000479"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBH1826368.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGCLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            40783..42675
                     /gene="pepF"
                     /locus_tag="KRN00_000480"
     CDS             40783..42675
                     /gene="pepF"
                     /locus_tag="KRN00_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH1826369.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            42789..43754
                     /gene="galU"
                     /locus_tag="KRN00_000481"
     CDS             42789..43754
                     /gene="galU"
                     /locus_tag="KRN00_000481"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH1826370.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            44254..45858
                     /gene="rho"
                     /locus_tag="KRN00_000482"
     CDS             44254..45858
                     /gene="rho"
                     /locus_tag="KRN00_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBH1826371.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            46011..46211
                     /gene="rpmE"
                     /locus_tag="KRN00_000483"
     CDS             46011..46211
                     /gene="rpmE"
                     /locus_tag="KRN00_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBH1826372.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            46356..47249
                     /locus_tag="KRN00_000484"
     CDS             46356..47249
                     /locus_tag="KRN00_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBH1826373.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            47267..48115
                     /gene="prmC"
                     /locus_tag="KRN00_000485"
     CDS             47267..48115
                     /gene="prmC"
                     /locus_tag="KRN00_000485"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBH1826374.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            48159..49223
                     /gene="prfA"
                     /locus_tag="KRN00_000486"
     CDS             48159..49223
                     /gene="prfA"
                     /locus_tag="KRN00_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBH1826375.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            49352..50032
                     /locus_tag="KRN00_000487"
     CDS             49352..50032
                     /locus_tag="KRN00_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBH1826376.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIALHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            50061..51101
                     /locus_tag="KRN00_000488"
     CDS             50061..51101
                     /locus_tag="KRN00_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBH1826377.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGIDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            51118..51567
                     /locus_tag="KRN00_000489"
     CDS             51118..51567
                     /locus_tag="KRN00_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBH1826378.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            51584..52036
                     /gene="rpiB"
                     /locus_tag="KRN00_000490"
     CDS             51584..52036
                     /gene="rpiB"
                     /locus_tag="KRN00_000490"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH1826379.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            52072..52701
                     /gene="upp"
                     /locus_tag="KRN00_000491"
     CDS             52072..52701
                     /gene="upp"
                     /locus_tag="KRN00_000491"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBH1826380.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            53002..53817
                     /locus_tag="KRN00_000492"
     CDS             53002..53817
                     /locus_tag="KRN00_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBH1826381.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDTVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            54043..54480
                     /locus_tag="KRN00_000493"
     CDS             54043..54480
                     /locus_tag="KRN00_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBH1826382.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            54665..54892
                     /locus_tag="KRN00_000494"
     CDS             54665..54892
                     /locus_tag="KRN00_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBH1826383.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            54897..55283
                     /locus_tag="KRN00_000495"
     CDS             54897..55283
                     /locus_tag="KRN00_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBH1826384.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            55286..55990
                     /gene="atpB"
                     /locus_tag="KRN00_000496"
     CDS             55286..55990
                     /gene="atpB"
                     /locus_tag="KRN00_000496"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBH1826385.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            56059..56319
                     /gene="atpE"
                     /locus_tag="KRN00_000497"
     CDS             56059..56319
                     /gene="atpE"
                     /locus_tag="KRN00_000497"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBH1826386.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            56442..56939
                     /gene="atpF"
                     /locus_tag="KRN00_000498"
     CDS             56442..56939
                     /gene="atpF"
                     /locus_tag="KRN00_000498"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBH1826387.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            56936..57481
                     /locus_tag="KRN00_000499"
     CDS             56936..57481
                     /locus_tag="KRN00_000499"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBH1826388.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            57498..59000
                     /locus_tag="KRN00_000500"
     CDS             57498..59000
                     /locus_tag="KRN00_000500"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBH1826389.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            59028..59906
                     /gene="atpG"
                     /locus_tag="KRN00_000501"
     CDS             59028..59906
                     /gene="atpG"
                     /locus_tag="KRN00_000501"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBH1826390.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            59919..61313
                     /gene="atpD"
                     /locus_tag="KRN00_000502"
     CDS             59919..61313
                     /gene="atpD"
                     /locus_tag="KRN00_000502"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBH1826391.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            61316..61576
                     /gene="atpC"
                     /locus_tag="KRN00_000503"
     CDS             61316..61576
                     /gene="atpC"
                     /locus_tag="KRN00_000503"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBH1826392.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            62038..62418
                     /locus_tag="KRN00_000504"
     CDS             62038..62418
                     /locus_tag="KRN00_000504"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBH1826393.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRLFNFKDIEVLRNEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            62433..62894
                     /locus_tag="KRN00_000505"
     CDS             62433..62894
                     /locus_tag="KRN00_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH1826394.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            62915..63505
                     /locus_tag="KRN00_000506"
     CDS             62915..63505
                     /locus_tag="KRN00_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826395.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            63520..64677
                     /gene="alr"
                     /locus_tag="KRN00_000507"
     CDS             63520..64677
                     /gene="alr"
                     /locus_tag="KRN00_000507"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH1826396.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEKSVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            64710..64997
                     /locus_tag="KRN00_000508"
     CDS             64710..64997
                     /locus_tag="KRN00_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBH1826397.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            64966..65349
                     /locus_tag="KRN00_000509"
     CDS             64966..65349
                     /locus_tag="KRN00_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBH1826398.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            65520..66347
                     /locus_tag="KRN00_000510"
     CDS             65520..66347
                     /locus_tag="KRN00_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH1826399.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            66340..67281
                     /locus_tag="KRN00_000511"
     CDS             66340..67281
                     /locus_tag="KRN00_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH1826400.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            67704..68798
                     /locus_tag="KRN00_000512"
     CDS             67704..68798
                     /locus_tag="KRN00_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826401.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            69024..69440
                     /locus_tag="KRN00_000513"
     CDS             69024..69440
                     /locus_tag="KRN00_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826402.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(69622..70191)
                     /locus_tag="KRN00_000514"
     CDS             complement(69622..70191)
                     /locus_tag="KRN00_000514"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBH1826403.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLKKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNS"
     gene            70345..71502
                     /locus_tag="KRN00_000515"
     CDS             70345..71502
                     /locus_tag="KRN00_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBH1826404.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKIVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDEALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            71667..72022
                     /locus_tag="KRN00_000516"
                     /pseudo
     CDS             71667..72022
                     /locus_tag="KRN00_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(72404..73156)
                     /locus_tag="KRN00_000517"
     CDS             complement(72404..73156)
                     /locus_tag="KRN00_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH1826405.1"
                     /translation="MEKKSPIIKNIVDSFRIIDVINEKGSIGIAKISEILSIPKTSVF
                     RIVKTLEEIHVIKQLENSDYTLDYRLLSYAKGTSQENKLISVAEPYLQKISKETGESV
                     NLGIRYQNEVIIVKSIEGEFYQLQTTLIPVSPLYCSGMGKLFLSQESEEFLQDYFNNL
                     EKRTVNTITEYNEFLLAKKRILELNLSIDNEEYEYGLSCYAVPIFDCNNDLICAISIT
                     GPSNRLMHKGEEYLIKVLKEQANNLQTEFSKL"
     gene            73406..74323
                     /locus_tag="KRN00_000518"
     CDS             73406..74323
                     /locus_tag="KRN00_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBH1826406.1"
                     /translation="MKVSIIGAGAVGATTAFTLAKTSFVDEIAIVDIDQNRAKGNALD
                     ILHGLSLMHETRIVSGDYDCAINSDVIVITVGVPEKVGESRLVPLQKNVKILQDIIPK
                     ITSTSPNGLLLVVSNPVDIISYFSQKISGWEAKRVIGLGTTLDSARLNYLIARDLKIS
                     QTDIQGLVIGEHGDSQVVAWSQTSVKGTPFLDYVKSNNISLQEDYCNNLAQEVKDTAF
                     DVWDMKGPNCYCVALAIERVIKAIARNEHAILPVSQPADSEMYISQPHIIGRDGVQRR
                     VILSYDTQELNAFDTSYQSLQDIVKQIEI"
     gene            74342..75019
                     /locus_tag="KRN00_000519"
                     /pseudo
     CDS             74342..75019
                     /locus_tag="KRN00_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898696.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            75035..75673
                     /locus_tag="KRN00_000520"
     CDS             75035..75673
                     /locus_tag="KRN00_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside recognition domain-containing
                     protein"
                     /protein_id="HBH1826407.1"
                     /translation="MDHFALIFLGITLIGIILAFINVRIPPISNYPDTYVDGSTTSKI
                     VSSTQGTRLQRAIIQSSMRANQVTLKNFTSKIDNMSFYVLWLTPIIIFWGALALIVSL
                     YTPLLTWVSYPIELVLKLANISEPAITASAIMSGFADNYLPVILGKGLESIESKTIIT
                     MMSILQLIFMSEIATLLQSCKVVKSFKDIIIIFLQRTIIALPFVIIFTKLIL"
     gene            complement(76261..77415)
                     /gene="nagA"
                     /locus_tag="KRN00_000521"
     CDS             complement(76261..77415)
                     /gene="nagA"
                     /locus_tag="KRN00_000521"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH1826408.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNITDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSIARLNSGSLAGSVLTMDKAVRNIVDWNIATLEDAIKM
                     ATYIPALSCNIDNVCGSIHQGMEADFIVTDKDFNIYETYISGICMYKVNK"
     gene            complement(77498..78223)
                     /locus_tag="KRN00_000522"
     CDS             complement(77498..78223)
                     /locus_tag="KRN00_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1826409.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            78492..79421
                     /gene="pfkB"
                     /locus_tag="KRN00_000523"
     CDS             78492..79421
                     /gene="pfkB"
                     /locus_tag="KRN00_000523"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH1826410.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDSVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLGEIDKYQDLVEVKKLS"
     gene            complement(79544..80461)
                     /locus_tag="KRN00_000524"
     CDS             complement(79544..80461)
                     /locus_tag="KRN00_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1826411.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVRFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAISGEECIKAQRLLEKIINSVK"
     gene            80932..82101
                     /locus_tag="KRN00_000525"
     CDS             80932..82101
                     /locus_tag="KRN00_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1826412.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            82150..83001
                     /locus_tag="KRN00_000526"
     CDS             82150..83001
                     /locus_tag="KRN00_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBH1826413.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
BASE COUNT        32949 a         9130 c        15046 g        25984 t
ORIGIN      
        1 aataattata aactaaagta aataaaatat tgagcgatta ttaaaaagat atatatataa
       61 tttaatttga gcagtttgtt atatattata aaaaaagaga aaaataaaag gtaaattgtt
      121 tctggataac ttaaaattgg aagtaagaat atttaactag agaagaatta tttaagttta
      181 ggttagctct aggagtagct gattttatag gaacaataga ttttatggat gatgatataa
      241 acatggtagc aattagatca gaagatataa gggtagaatt taatagagat ttcaaagaaa
      301 ttatagacct caaactcaaa ccgtatcgat ataaaaacta aagttagatg atatagtgtt
      361 gtatatagga ccatcagctg ttatggcagt attagtgctt ttaacaaata taatagtaaa
      421 acttttgtat gaattgataa taaaaaaatt aaaaaccaag acataaaaat ggcaacaaaa
      481 agaagttgaa taagggaggt aaaaatgaaa tttaagaagt tagtctcttt gggaatatta
      541 tcaacacttt tattgagtgt aataactgga tgtagtaatg tttcatcagg ttcaaactta
      601 aagtctaata ataagacaaa aggagagtta acagtttata cagcaattga agaagatagt
      661 atagatacat acttagctac atttaaagag aaatatccag atattaaatt gaatgtactt
      721 agattatcag taggaggtat aacagcaaga ttattagcag aaaaagataa tcctaaagca
      781 gatgtgttat ggggtgttgc agctacaagt ttgataattt tagatgacaa agaaatgcta
      841 gagccatacg ctccgaaagg ctttgataag gtaaattctg catttaaaga tgataagaaa
      901 gttccttctt gggttggaat agatgcttgg atgactggta taacagtaaa tactaaagaa
      961 ttaaaagcta aaaatatatc agctcctagt tcttatgaag atttaataaa gccagaatat
     1021 aaagatctta tatctatgcc tagtccagct tcttcaggaa caggatatct aacagtatca
     1081 gaactcatac aaattatggg tgaagaaaaa gcatggcagt atatggataa attgcataaa
     1141 aatattggtg tatacactca gtctggttca gctccagcta tattagcagc ttcaggagaa
     1201 tatcccattg gtatatcttt tggaaataga ggtataaagt taaaaggtga aggttatcca
     1261 gtagaagtag tatttccaaa agaaggttct ggatgggaga tagaatcaaa tgcacttgtg
     1321 aaaaaagata atataaaaga agcatcaaaa gtatttttag attgggctat aagtaaagat
     1381 gcaatgaatg agtattctaa gaattttgca gttactacaa ttgacacggg aaatccggtg
     1441 ccagaaggat ttccaaagaa tccattagaa cagatgatag ataatgattt aaaatcagca
     1501 gcaagaaata gagaggctat actaaataaa tggatagaaa aatatgatgg aaagacagaa
     1561 aaagagagct aagccttaca ataaaattta gtacaaaaag cgcctagaat ataagtttta
     1621 tatctaggct cttttgatat atttatttaa aatgcatatt tctatataaa aataaatagt
     1681 ttagtacctt gattaaatta aataaaaacc ttaaaataaa gagatgtaaa gaaaaactaa
     1741 aaacgaataa aaggtgaatt tatatgataa aagaaataat agtagtagag ggtagagatg
     1801 acgttacagc agttaagaga gcaatagatg cagaacttat aactacaggt ggatttggat
     1861 ttccaaaagg tgtaatggag cgtataaaag ctgctaatga aagacgtggt gttataatat
     1921 ttacagaccc agattttgca ggtgaaaaaa taagaaaaaa aatagcatca gaagttccag
     1981 gatgtaaaca tgcatttcta ccgagagagg aagctaaaaa ggatggagat ataggtattg
     2041 agaatgctac tcctcaaagt ataatagcag ctctgaataa agttagaact gaaaatacag
     2101 aaaaaagaga tgaatttaag caagttgact taattagaaa tggtcttata ggtaatgaag
     2161 aagcatcact tagaagagat gcacttggaa aaatacttgg aattggatat ggaaatgcaa
     2221 aacaattttt aaatagattg aataattatg gagttgaaag agaagaattt atagatgcat
     2281 taaaacaaat ctaaacgtaa tatttaatgt atgaaaaata tgtatataaa ataaattgtg
     2341 gaattacggt taatttaaga taaattattt ataatatata ccttatttta aatcaatgta
     2401 aatacatata aataagtata attaataaaa ttaaatatca aaataagtta aaaaggagta
     2461 aataatggat agactatctt cacataatgc aacaaaggaa gtagtacaaa aatataattt
     2521 taaattttca aagtctttag gtcaaaattt cttgatagat agtaatataa ttgataaaat
     2581 cttatctgga gctagaatca caagaggaga taatatcata gaagtaggac ctggtatagg
     2641 aactcttact cgtgagatgg gtaaaatagc agaaaaagta gtggctatag aaatcgatag
     2701 aaatttaatt cctatattga aagatacctt gtcagattta gataatacag aggttgtaaa
     2761 tcaagatata ctaaaagtag acatacagga attagtaaaa gataaattaa atggtgggcc
     2821 agttaagctt gtagcaaatc ttccatatta tataactact ccaatagtta tgaaattttt
     2881 agaggaagac atacctgtaa cagacatagt agtcatggtt caaaaagaag ttgcagatag
     2941 aatgaatgct attccgggta ctaaagatta tggggcatta tctatagctg ttcaatacta
     3001 ttgtgataca gagattgtgg caaaagctcc aagacatatg tttataccac aaccaaatgt
     3061 agattccaca gttataggtc tacatgtaag agataaaaga aaatatgatg ttcataatga
     3121 agacatattt tttaaaacag taaaagcatc ctttggacaa agaagaaaaa ctcttcttaa
     3181 ttcgttggga ggtcttggtt ttcttaataa agatgaaata agagaagtat taaaagaagc
     3241 taatatagac gaaaaaagaa ggggtgaaac tcttagtata gaagagtttt cagttctttc
     3301 aaatataata aatacaaaag tatcttctaa atagaaggta ctttttttaa ttttgttaac
     3361 atatattgtt tagagaaact gtgttaaggg gggattgcag tgggttctaa aagaaagttt
     3421 aaaagagact atataatact agaagctaaa gacataaact ttagatacaa agaacgagta
     3481 ctgccaaaag cttttgcaaa agttgaagta aatgatgaaa aagcaattat tgcattatat
     3541 gtagaaaatc taaaatatgt taaagatggg tataaagcag tagcaataaa agatgaccat
     3601 ggattaatag acttaggaaa tataatttta aatgaacaag gaagaggtga atttgtttta
     3661 gatttagaag attatgatga tgagataaaa ggtattgcat tattgtatga aagaaatata
     3721 cctttaattg gatttaaagg aaataagctt gaaaattatg aggacatatt atttcaagag
     3781 gtagaggaag aagaatatga agaatatgaa gaatatgaag agttggaaga agaagacgaa
     3841 gagatagagg agaatgagga aagtgataga gacgaagata gtgaagaaga atatattata
     3901 gaagaatatg atgaagatga gtatgaagac tattgggaag atgatgaaga tattgaagaa
     3961 ggagagttaa aagcaagaac ggaagtagaa gattctgatg atgaggaaat agaagagttc
     4021 aataattata aggaaataga aaattataat agggttaaag tacaggaaga atatatagac
     4081 atagaatatg atgaggaaga agaggaagaa gaagaagttt ttgaagtaaa tagagaagaa
     4141 gataggtttg tttcctcaaa acctactaaa tcaaagaaag ttcaaaaaga tcagaataat
     4201 attgaaaaaa taaaaagagc taatggagta agtcaaggag agagtggaaa taaacaaacc
     4261 agtacattac ttatgccaag acaaataaaa aaaggtttga aattatttaa agaagtaaaa
     4321 ccttttgtaa cagattatat agataagaca agatggtgga aaatagagat aaatcctaca
     4381 acactgtgtg gatatacaat gccttattta ggatatttaa acgtgttgaa ttacactatg
     4441 tatagtgatg cagttttaca ttcatataaa tacagacact atttatttgg agttcagtat
     4501 gatgaatata ataaaagaaa acattatatt tatgctatcc caggaaatag aaatgaacag
     4561 ccagacaatg gaagcacagg atttttaaga tatcaagctt gtgataatag aacaaatagt
     4621 ttaggatatt ggctatgttt tatagattct agacaaagaa atatagttag gtaaaaataa
     4681 taaaaatgaa aaaatttaga ctcaattctt attttactga aaaaattaat gaaatgtagt
     4741 acaaaacttt aaaaactatt gataatattt aaatattaca ctacaatata tcttgaaata
     4801 cctattatat tatggaggaa aattatgata aacgagcaaa gaattttaaa tgagtttctt
     4861 gaattagtac agatagatag tttatcttta aaagagggga atgttgctaa agtattagtt
     4921 aaaaaattag aagaaatagg ttgttcagta gtaatagaca atgctggtga aaaagcaaat
     4981 ggagaaactg gtaatataat agctacatta aaaggaaata aagaaggaaa gaaaatatta
     5041 tttagttcac atatggatac agtaactcca ggtatagggg taaaacctat agtggatgaa
     5101 gcaaatggaa taataaaaag tgatggtact acaatattag gttctgatga taaagcaggt
     5161 atagcagcta tattagaagg cttaagatat ataaatgaaa ataatataga acatactgat
     5221 atacaagttg tattctctat atgtgaggaa tgtggattag ttggagctaa aaatttagac
     5281 tatggaaaaa tagattctga atatgcattt atattagata gtggtggttc tccaggtgaa
     5341 ataatagtaa aagctcctgc acaagatgta ataaatgtta agatattagg aaagactgct
     5401 catgcaggtc ttgaacctga agctggaata agtgctataa tggtagctgc cagagcaata
     5461 gaaaatatga atttacttag aatagacgaa gaaacaactg ctaacatagg aattataaac
     5521 ggtggaacag ctacaaatat agtaacagga gaagttaata tagttgcaga agccagaagt
     5581 ctaaaagaaa ataaattaga tgttcaaact aaacacatgg tagagacttt tgaaaaagct
     5641 gcaaaagatt ttggagctca aattgagata gatgtcaata gagcatacac accaatagat
     5701 gttagtgagg attctgaaat aataaaactt gcaaagaagg ctttttcaaa cttaggtata
     5761 gaaggtcata ctgaatctac aggaggaggt agtgatacaa atatattaag taagaatggt
     5821 atcgaagcta taactttagg aattggtatg aaaaatgctc atacactaag tgaacatata
     5881 gctataaaag acttatatga ttctgctaaa atggtagtgg agataataaa ggaagcataa
     5941 atttaaataa tagtgtataa tatatatatc gcctagctta agctaggtga tttttcattt
     6001 tatagaagat tgataatctc tattgaaagc aaagagtata catttgcata taagagagtg
     6061 tttaatttat gttcaaatgt aggttcttaa taatatttag attgtttcat aagggaggaa
     6121 taaatatgga aacaaggtat gaagaagcaa ataaaataac aatacaatca atactttgga
     6181 atgtagtatt aacaataatt aaggttatag ctggtgttat tggtaattct agcgctatga
     6241 ttgcggatgg attacattca gcatcagata ttataagttc tataggagta ctaataggca
     6301 attatgtatc ttctagacct ggagatagag agcataatta tggtcatgag aaagcagaga
     6361 cattagtatc atttgtgtta tcaatattgc ttattttcgt ttctataaca ataggtatag
     6421 aggcaattaa atctttattt aacttagatg cattaagtgt tccatcaata ttaccattag
     6481 tagtatcagt tatttcaatc ctgataaaag agtatcaata tagaataaca ataaaagttg
     6541 ctaaaaagat aaattcacca gccctaaaag ctgatgcttg gcatcatagg tcagatgctt
     6601 tatcttcagt agctgctttt ataggtatag gtggttctat tttagggttt aaaccattag
     6661 acccaattgc gtcagttgta gtggctatat ttgtagctaa agtaggaatt agtatactta
     6721 taagttctgt taatgaattg atggatgttt cagttgatga agaagagata aaagaattaa
     6781 aatttattgt agcagataca gaaggtgtta aaaatcttgg tgatataaag actagaaaac
     6841 atggagctat ggcatatgta gatttgacta tatgtgtgga tgaaaatttg acagttaagc
     6901 aaggtcatga tattgctacc aagcttgaaa aacatataat aaaacatatg gaatttgtaa
     6961 aaggaataac agttcacgtt gaaccatgta ctaattgcca aggaaataag tgtaataatt
     7021 aattaaaact taaaaaaaag tgtaaaaagt tatataattg ttttatgatt ataaactcta
     7081 ggggtggtta aatgagcaag aaaagaaaac taaagaaaaa agctgcaata ttaataggag
     7141 tagttgtttt ctttataata tactttatat cctttagaat aggaataaat atggaaaagg
     7201 ataaaagtga agtgccaaag aaggtagaaa aagaagaaga agataatagg tctttaagga
     7261 ctcaaataaa agagaagaag aaggtttata tatcagataa aaatatagaa aacataaaaa
     7321 ttgaagaaga tatgtgggat gaaataaagt tatttttctc agattttaag aaagtaagaa
     7381 atactacttc ttcttacgaa gcagtttatg aaggttattc tgatgatgga gttaaatttt
     7441 ctactgacct taactttttt agagtatata ctgtaaataa agaagaatat tataaagtac
     7501 cagttagttc taaggatgct tttaagaaac ttttagatga gagtatatat acttcgtttg
     7561 accttttaag tcattataaa gattggaaag aggttactat aactcatgga aaagaaatta
     7621 aaaaagttca tagatggaaa tttgatgatt tagcacataa gatgatttca aagagggttg
     7681 taggaaaagt tcaacctgag aaaagtaagg aaagaagtga ctataatttt actataaata
     7741 taaaaggtga taattttgat gtaaaagttg atacaatggg aaaagattat gtaaaagtta
     7801 cttctaagaa aaatgtatct tactatgagg ttcatacaag tttatttgat taccttaaaa
     7861 atgagatatt tgaaattgga aagaaataag actttaagaa ggctatcaaa ttagatattt
     7921 gatagcctaa attattttta tatattattt ttcaaccaac aagtctgcaa ccttataaat
     7981 tggaccagca ccagcagtta ttactaaatc attatcctta acattttcac gtaagtattt
     8041 tactatatct tcaaattctt ttatatagat ggcatctaca ttattttgat ataatttctc
     8101 aaccaagtcc ttagaatgta tatctccagg gtctttttcc ctagcagcat atatatctgt
     8161 tatgataact ttatcagcag catagaatgc ctctgaaaat tcacctaaaa gagattttgt
     8221 tctagtataa gtatgtggct ggaagataca ccataaagtt gattttttta attttttggc
     8281 agcagctaaa gttgctttta actcagttgg atgatgtgca taatcatcta ctactaaagc
     8341 attcttataa taccctttag tttcaaatct tcttccgaca cctttataaa tttttatatt
     8401 ttttcttata gtctctaagt caataccaga aacaagagct gccattatag cagaagaagc
     8461 attgtatatg ttatgaagac catatacaga aagttcaaat tctcctaaat ctcttccttc
     8521 atattctatt ctaaatattc catgaccact attgtcaaag tgaatatctt ttattacagc
     8581 atcattgtca gaatctctac cgtattttat aatagtagct ttaacatcat acaatatgtc
     8641 atcaatattt tcatcatcgc catttattat gaaatagcct tctgggggta ataattttcc
     8701 aaatttgtta aaagaagcct tgatttcatc tattccagag aaataatcaa gatggtcttc
     8761 ttcaacattt aaaactatag atatctttgg gttaaaatta aggaaactat ctacatattc
     8821 acatgcttca gttataaagt ggttggaatt acctatctta acattaccac ctatcatact
     8881 taagttacca ccaactagta tagttgggtc taagtctgca tattcaaaga ttgtagataa
     8941 catagatgtt gtagaagttt ttccatgtgt tccagaaact gctatagaat ttttatattc
     9001 cctcatgatt tggcctaaaa aagttgctct gttcattacc aatttatttt tttctttagc
     9061 agccacaagt tcttcattat ctggatgaac tgctgctgta taaacaacca tatttacatc
     9121 atctgatata ttatcttttt tctgaccaat ataaatagtt gccccttggt ccctaagttt
     9181 gtctaatagg tatgattcgt ttgaatccga acctgaaact tgataacctt tattgataca
     9241 tatttcagct aatgcactca tgctgatacc gccaattcct ataaagtgta tattcataat
     9301 aaaaccacct ttctttttaa ttaagtccta caatatgaac tatttctgtg gtataataat
     9361 ataatgttca atattttata attaatatgc atataatatt atatgtattt tatttttgaa
     9421 tataataaaa cataagtaat attataccac aataagaatt gttatgcatt agttagttta
     9481 acgttatata aaggtacttg taggaggaaa taataatgaa atttaaaaga acagagagaa
     9541 ttggagcaat agttaaaata ctgtctgata atccaaataa aatatatact ttaagttatt
     9601 ttacaaatca atttaatgca gcaaaatcaa caataagtga agatttatta gttgtaaaaa
     9661 atgtatttga gaagttacat ttaggtaaag ttataactat ttcaggagca gcaggaggag
     9721 taaaatatat acctaaaact tctatagcag aaaatgcaga gttcttaatg gaattatgcg
     9781 agagaatatg tgacaagtct agaatactat ctggtggttt tttatacttg attgacctaa
     9841 tttacgaccc tacaatagct gctaagatag gaaagatatt cgcatcaaat attgagtatg
     9901 tagatgcaga ttatgttgtg acaatggaaa caaaaggtat acctatggca cttatgactg
     9961 caaaagctat gaatttacct ctagttataa taagaaaaga tataaaggta tcagaaggtc
    10021 ctacacttag catgacatat gtgagtggaa acagttctaa agttgaaagt atgagtttgc
    10081 caagaaaagc tcttaaacca gatagtaaag ttataattat agatgatttc atgaggggtg
    10141 gaggtactat aaaaggaatg gtagacctta tgaatgaatt tggtgcagag gttataggta
    10201 ctggagtatt catatctaca acgaatcctt cagaaaaaat ggtaaaagat tatatttcgt
    10261 tgattcaatt ggatgttaat ggagataaaa tagtagtaga accaaactta aagactttta
    10321 aagatgaata tagaaatgaa gatttagacg aagaagaaga ttcagaattt gaatttgaga
    10381 tagatgaaga ttaataaaaa aaatatttag aaaaatatgt aaaaataaaa agaggatatc
    10441 cctagttgtt catagaatta tttaaaaaac agtttatatt aatttattcc agcgataata
    10501 attttaatat aaattaattt ctgtcaaaat caaaggggga tattttggta tgaagataac
    10561 tgacgtaaga gtaagaaaat taacagaaga aggtaagatg aaatgtatag tttcaataac
    10621 tttcgataat ttgtttgtag tgcatgatat aaaagttata gaaggccata atgggctatt
    10681 tatagcaatg cctagcagaa aagtaggcga aggaaatttc agagatatag ctcatccaat
    10741 aaatgcagaa atgagacaag ttttagaaga tgcagtttta caagcgtatc atgaagcatt
    10801 agttcaatgg gaagtagctg ctgaataata ataaatatat aaaatggaga gagcccgaac
    10861 atttaggctc tttttaaatg tagaatttct attaaaatat gtacttttta gtaaaaaagt
    10921 gctatattat tagtgataat gtatatgttg tatacaaatt gttagataaa tgtattataa
    10981 tgtatattga ttaagagaat aatacgaata aaattaaatt agattgaatg gagtgtatca
    11041 atgaacttta aagctataat ccttgctgct ggcaaaggaa caagaatgaa gtctaaatac
    11101 ccaaaagtta tacataaagt atgtggaaaa gaaatggtta accatattat agatgtttca
    11161 aaaaaatcag gggtaaaaga tactgttgtg attttaggac atgaagctga ggtagttaaa
    11221 gaaaagcttg cagaagaaat tataatagcc atgcaaacag aacaacttgg gacaggacat
    11281 gctgtaaaga tggctaaaga atatattaat gatgaagata caatagttgt actttgtgga
    11341 gatactccac ttataaaaga agagacacta aagagactat ttgaatatca tatagaaaat
    11401 aaatatcatg ctacagttct tacaacaaga gttggaaatc caacaggtta tggtagaata
    11461 ataagagata agaagggtga ccttcttaaa atagtggaac aaaaagatgc aaattcagaa
    11521 gaaaagatga taagtgagat aaactctgga atttattgtt ttaatggaaa gagtcttaga
    11581 gaagcactag atttgctaaa taataacaat tcacaaggtg aatattattt aactgatact
    11641 gctaaaataa tgagagataa aggattaaaa gttggtgcat ttgcaggttc aactattgaa
    11701 gaacttatgg gcgttaactc aagagtagaa ttatcaaagg cagaagaaat tatgagacga
    11761 agaataaatg aatctcatat ggtaaatgga gtaactataa tagacactaa ctctacctat
    11821 atagaatctg atgttatgat aggcaatgat actataatat atccaggtgt tatgttacaa
    11881 ggaaaaacaa ggataggttc agattgtata attggaatga attcatctat aacaaattca
    11941 gaaataggtg atggtacaga aataaaaaat tcaactataa ttgatagtaa ggttggagaa
    12001 aattctactg ttgggccata tgcatactta agaccaaaga gtgacttagg aaataatgta
    12061 aaaataggcg attttgtaga agtaaaaaat gctattatag aagatggctc aaaagcatct
    12121 cacctttctt atataggaga tgcacatgtc ggtaaaaatg taaatattgg atgtggagta
    12181 gtatttgtaa actatgatgg taaaaataaa tttaaatcaa tagtaaaaga caatgcgttt
    12241 ataggttcaa attctaattt agttgcacca gtagttgtag aagaaaaagg atatatagca
    12301 acaggttcaa caataacaca tgatgtccca gatggtgctt tggcaatagc aagagaaaga
    12361 caagttatca aagaaggatg ggtagaaaaa aagaatcaaa aagacgacca aagtaagtaa
    12421 ttatgtagtt tattattttg gctaaaaaat ttagctcgaa attattataa attatattca
    12481 ttagtatttt aaaattttca ggagggttac ataaatgaat actagcggaa gcgagattaa
    12541 aattattgca ggtaattcat cgaaagagtt agcacaaaaa atagctgact atataggtgt
    12601 atcagtacta gattgtgaag taggtacatt tagtgatggt gaaatatgtg taaacatgaa
    12661 tgagacagta agaggttgtg atgtgtttgt agtgcaatct actaacagcc cagtaaatga
    12721 taacttaatg gagttattaa tcttaattga tgcgttaaag agagcatcag caggtagaat
    12781 aacagcagtt attccttact atggatatgc aagacaagac agaaaggcta aggcaagaga
    12841 tccaatcact gctaaattag ttgcaaattt aataactgct gctggagcag atagagtatt
    12901 aacaatggat ttacatgcag ctcaaataca aggatatttt gatataccat tagaccactt
    12961 actaggtgga acaatattag caaattattt taatgaaaag aaaatagaag atttagtagt
    13021 agtatctcct gacttaggaa gtgttactag atcaagaaaa tttgctaata ctttaaatgg
    13081 agaagttcca atagctataa tagataaaag aagaccgaaa gctaatgtat gcgaagttat
    13141 gaacttaata ggtgatgtta aaggtaaaaa tgttatacta ttagacgata tgatagatac
    13201 agcaggaaca atagttaatg ctgcaaatgc acttaaagag tttggagcaa aagatgttta
    13261 tgcttgttgt actcatggtg tgttatcagg tccagctatt gaaagaattg ctaattcaga
    13321 aataagtgag ttaatagttc ttgatactat acaacttcct gaagagaaaa gaatagataa
    13381 gataaagata aaaacagtag ctcctttatt tggagatgct ataagaatga tattctctaa
    13441 tgaatcagta agtaaattat tctaatttat tgtatttatg agagttgttt aaaaggatat
    13501 aaaccttttg agcaactctt ttttgatttt ataattatgg aatgttattt ttttcttgtt
    13561 agaaaggtat atattattgt aaaaagagat tatagtttaa aattatgtat atttaagtaa
    13621 aataaactta ataaaggaca tattattcaa aatattatga atataaaaaa tattacaaaa
    13681 aagtattgaa aaaattcaga ttatgtagta ttatgtaaat ataaataaag aaagaaagag
    13741 gtgtttccaa tgggaaggtt agaagatgaa cccctaataa ttaaatgatt cagtcacaat
    13801 ctaaagtgaa tataaaaatc tattgaaagt ttatttataa gaattgaaaa tagtatctat
    13861 tctatcttta gtgtttgtga gagggttctg gattatataa gattactgta aagaagtaat
    13921 tttgcacaat aagcatatct gtaaatgaag agtttcgttt atataatgat tgtggctgaa
    13981 tcataactat aatagataga atgtttataa tagatgattt tataaaatac tatattgtaa
    14041 tagcttttag ctttcaaata aatattagca aaggatggaa atgacaatga taaaactaaa
    14101 tgataattta taaatatctc cttacgatat ataataattg tagggagatg tttctttttt
    14161 ttgtagagta taatttttct agaaattctg tttcaatatg taaaaagttg gtatatataa
    14221 atagtataaa cagtgttgct aaaatatggt agatattata taatataaat ggatatgtat
    14281 atacattatg agttatataa tttgaattta ataaaataga aacgttgatt tatgttctgt
    14341 aatgtgggca ccttggagca tattgagtta gtggtgcaac cggctatgaa attgtattta
    14401 tttataaata ctattatttt catagctttt tttatttaaa aaatggttat atgttagaaa
    14461 taaatttggt tagtacgttt aaataatttt acttagattt ttaaccagat atattataag
    14521 taagtattaa ttaaaaaatt taagggggaa taaaaatgaa gttaaaaaag aataaaaaag
    14581 gtttcacttt agtggaatta ttggtagtaa ttgcaattat aggtatatta gcagtagtgg
    14641 cagttccagc tttatttagt aatataaaca aggctaaggt agcaagtgtt gagtctgatt
    14701 atagttcagt taagagtgct gcattatctt attattcaga tactaataag ataccagtta
    14761 caccagatgg tcaaactggt ttaagtgttt tagaaactta tatggagtct cttcctgata
    14821 aagctgatat aggtggagaa tataaattga ttaaagttgg tagtaaattg gtattacaga
    14881 taggtacaaa tactgaggga gttaccttaa cagaagcaca atcagcaaaa ttattgagtg
    14941 atataggtga aaaaaaaata tatacaagcg ctacaacaaa tagtttggga gatccattaa
    15001 caagtaatac aaaaatagat aataaagttc tatatatagt acttatagat aatactgtga
    15061 tggacacaac aaaatagtta aaacaatatt tttataaaga atattgtaaa tttaatgaaa
    15121 aatataatat aaaagacagg aagaaaatct tcctgttttt ttatactatt ttctttaatg
    15181 ttcaattatg aatgatgata taattgagat agtaaaggag tgaaacctgt ggctaaaaaa
    15241 gttagaatag gagacaaact ggtcgaaaaa ggatatataa cagaagaaca gcttaaatgg
    15301 gcactatcag aacaaaaaaa cagtggaaaa agactaggag aatttctagt acaagaaggt
    15361 cttatagata gtaacctact aataagtgta ttaaaagaac tcttggatat agaaagtata
    15421 tttttagaag ggacagaaat agacacttta gctacaaaga tggttccaga aaatatatgc
    15481 aaaagatata ctgtatttcc attcaaaata gatggaaata aaatatgtct agccatgtca
    15541 gacccacaag acagagaagc agttcaagat gtaaggcgta tgtcaggtaa agacgtagag
    15601 atatttatat caagtacaga agatataaac aaagcaatag gtcatgctta tgcacattca
    15661 gaaataaata aggcaatgac tgagtacaac aaaaatagaa ctggtggagt aagagaaaca
    15721 gtaatacttg aagaagatgt aaatgctgct ccaatagtac gattagtaaa taacatacta
    15781 gaaaatgctg ttagaatgga agcaagtgat atacatatag aacaaagtga aaattacatg
    15841 cgtgttaggt ttaggataga tggaatgtta agagaatata tgaggatgaa ctcagcacca
    15901 tataaggcag taatcagccg tatcaagata atgtcagata taaatatatc tgaaaagaga
    15961 ataccacagg atggtagaat ctatttaaaa gtagataata aacccataga ttttagggtt
    16021 tctacaatgc caactaacag ggatgaaaag atagctatga gagttcttga taagagtaat
    16081 tttatggtta gtaaagaagt actaggaata gacgaacatg gctctaagat atatgatgaa
    16141 ttgataaaca ctccttatgg tcttatattg gttgttggcc ctactggaag tgggaaaacc
    16201 actacattgt attcaatgtt aaatcaacta aatacagaaa atagaaatct attaacaata
    16261 gaagacccta tagagtatga attacctggt gtaaatcaat ctcaaataaa tgaaaaggca
    16321 gggcttactt tcgccagcgg acttagagct tttatgcgtc aagacccaga tataataatg
    16381 gttggagaga taagagatac tgagacagca gaaatagcaa ttagagcttc tcttacagga
    16441 catttagttt taagtacatt acatgcaaat acagcagttg gagcaatttc acgtctttta
    16501 gatatggatg tggaaagttt tttaataact tcatctgttt taggtgtaat atctcaaaga
    16561 cttacacgaa aaatatgtga gcattgtaag gtttcatatg aagcagatat tggagaaaaa
    16621 aaggctcttg gtattgatgt aaatgaatca gtaactattt atagaggaaa aggttgtgaa
    16681 aggtgtaata atactggata taaaggacgt ctaggtatat ttgaaatgct tgaaattact
    16741 ccagaaataa aagagttaat agattcatct gcaaatcaaa gagaaatttt aaagatggct
    16801 agaaaacaag gtatggttag cttaaaagag gatatagtta aaaaggtttt aaatggaaag
    16861 acaacagtag aagaaatgat tagaataatt ttgatgactg attaaaggat gatattatga
    16921 aaagttttaa atacacagta ataaaagagg acggaaaaaa gcaaactgat gtgattgaag
    16981 ccaacgattt taatgaagct agaaatcttc ttagaaagag aaatcttaga gttattgaaa
    17041 tcaaagaaag caaaaataaa aatataagat tatctagtag aaagagaaaa aaagacttag
    17101 gagctgacca gataagccac ttttgtagac agtttgctat tatagtatct tctggtataa
    17161 atagtatttc tggattagaa acattagcta gaaggtcaac taacattaca ttaagagaag
    17221 aaattaatcg tatagtggca gaaataaaag taggttctac tattgcagat tcaatgcttt
    17281 catcaaaatc aaagtttcca aagttactcg gtgctatggt agctacaggt gaagctacag
    17341 gtaaattaga tgaagtatta aaaagtatgg cttcatttta tgcaagtgaa cacagggtta
    17401 aacaaaagct tagaaatgct gcaacatatc cattaatagt tttgatttct tcatttataa
    17461 tgatttttat atttacaaca tttatggtgc ctaagatgat taattcaatt acaacagtag
    17521 gagcaactct tccacttata acaagaattg ttatggggtt tggtatgttt atgaagaagt
    17581 tttggataat agtactttta gttataatat tatttatcta tcagtttaaa aaatatctaa
    17641 aaacgtcagt tggaagggct cataaagata gagttataaa taagatacct gttttaggaa
    17701 aaggaataaa ttgtatggta gctacacgat tttcaagagc attgtatcta tttgtatcaa
    17761 caggataccc attagttcaa gggcttgatt atattataga tagtgtaaat aacaccatgg
    17821 cagagaagat tttagcatca gctaaagatg gaataacaag aggagaaggc ttagcagaaa
    17881 atttagagag atatacgtat tttgactctg tgttggtaca gatgatagct ataggggagc
    17941 agacagggga attagagaat ataagtagac agatggcaga attttatgag tatgaatccg
    18001 agatttattt aaataggatg gcctcaatga tagagcctgt tttaataatt gcagttggta
    18061 ttatagttgc gatactggtt gtatcaatat ttatgccaat gcttagtata tatgatgcca
    18121 tgtaggaggg aaaggacaaa tgaacaaggt ttatgtatca tattatggcg attatatttc
    18181 catagttgag ggcagatata aacacgataa ggataagttt tatgtaaaaa attttaatgt
    18241 gttttcaata gaggatattg cacaagattt ttctaaggaa aagtatgctc tattgagata
    18301 cgcattagaa aatgttaagt taaaatcaag acatgtagtt ttttgtttaa atacaagaga
    18361 tgtaatttta aaaccccaaa aacttcctaa tatggacaaa aaggatttag atggatttat
    18421 gaagctagag atggacgaaa tgatggcttt ggagtcagat gaatatgtat tttcgtatga
    18481 agtatctagt gaaacacctg ataattcaga tggcgatgaa tcaagcttaa atcttatcat
    18541 tggagctata caaaaggaag aggtaaatgc aattgtagag ataatgcatg aatttgattt
    18601 agtattagat agaatagata cattatcaac agcttactta agaatgctta aaaatttaga
    18661 ctacaatgat ataatggtaa ccaatataag tgacaatagc acaattataa atatatataa
    18721 gaaagatact ttatttatta gtgataatat acctataaag ataactgcta aagatatgga
    18781 catgcaatta ttaaatgtag tagaagaatc aaaaggtctt atgaattact attcgtcaag
    18841 aaactttggt aaggttacgg atactatatt aatattagga aaaagatatt ccaataaatt
    18901 aatttatgaa acttttagct ctgcattttc aagctatgtt tctcaaggcc ttactgagat
    18961 aatggatata tctgatatga taactggaga tatagatgaa gatgatataa attcaattgt
    19021 agagctttta ggaagtatga tagaacctaa agggaaaaga gattttgaaa atataaactt
    19081 tttaccaatg gatatactta gaaaacagat aaaagctaaa caaatgaaaa acatactgaa
    19141 aattgctcca atagttattt tgattcttgc tataccttat ttatgtttaa ttttttcaaa
    19201 taatttagca aataaggaac ttgaaaatgt taatggtgaa ataagaaata ttgaatctgc
    19261 atattatcag attggaaata tagaaaaaat gatacagagt aaaagcgaag aaataaaggt
    19321 atatgatatg ttaattggga aaaaggtaaa gtgggaaaat ttattggatg atatagataa
    19381 aaatactcca agtaaagttg aactaacaag tttatcaaca acttatcaaa atcttggaac
    19441 taataataaa gctgataatt caaaaagtaa taagactaca acagataaat caagtaacaa
    19501 tgaaacaaaa tcaagtacga aaagtgatag taatggagat aaaacagata atgatttaaa
    19561 tgaagataag actacaaatg tgtcagaagc attaactgga aatagtgaga ctaatagtaa
    19621 taacacggat aaagatgata aaactccatt gtatgataag ataccaaatg ttataaatat
    19681 agaaggaaat gctaaagatt cctcttatgt aggtcaattt ttatataaat taaagggatt
    19741 atactatttc aaggatgtta aattacatag cataaaaagt aatgcagaag attctaacta
    19801 tacatttagt atgacattat acctgaaaga aggtgtatta actaatgaat aaagatatat
    19861 ttaaaaaaga tataaaagat atatttaaaa tggaagttag tctaaaaggg attcttataa
    19921 aggttataat tttattagct attttatcat atggttattt tggactttac cctcaatatc
    19981 agaaatatat tgctacaaaa aattctgtaa aacaggctac tgaaaaatta aatatatata
    20041 aagagaaaac tgcacttatg ccaaaatatg aaaaacaact tgaagaagtt gaaagtgaac
    20101 taaaagaaaa aagcaaaaat cttttatatg atatgcaaga tggtcttttt ttaataggtt
    20161 tagataaaaa aatgaaggct tataatattg acttaaccag ttatgatgtt ggaaatgtta
    20221 aagaatacga acatttttat ggtatatcaa caacaataag tgttagaggt gattatagaa
    20281 atgtcaaaaa attaatggct tatttagaag aacaaaaaaa tgttactcaa atactagatt
    20341 atacaatgac ttcatatata gaaccagaaa aagaagagga agaaacaaca aacaataagg
    20401 atttaattaa aaatgtgaac ataaataaag atacaaaaat atactgggtg gaaggcgaaa
    20461 ataagtggca tttatataag gattgtccat tgataaaaga gggagagatt ataaaaaatg
    20521 acaaactttt agataggtct actaattatc tatgtaatac ttgtgtactt agagctgcaa
    20581 cagaaaaaga agcaaaaaaa gaagtcgtag ctccaaaggc agaaggtgta gtagatgcta
    20641 catttaaatt tataatgtac actaaagaga atactacaat gatacttgat acagataatc
    20701 catcttcatg gagaccagga aaatataatc catttaagtc tagtgcgaaa taaagctaag
    20761 taagctttaa agataggtga tgagtttgta caaaaataat aaaaaaggtc ttactttatt
    20821 agaagtaata atagctgttt ttatactgac aatagtttta agtatttctt ataaagtgtt
    20881 caatggtata acatcagcag taaaaaagca acagattatt acagatgctc aagtaaatat
    20941 taatctaatt aataagtatc taaatagaga tttggaaaac tgtaaagagc taactaaaac
    21001 tggttcaggt aataattatg aatacaatat agagatgcca gataatgttg taaaatatga
    21061 agtttctata gaaactaaaa aaaatacaga ggtatattct gtaacgagaa tccaaaacaa
    21121 tacaattgat acagaaaatg aagttagaga agagataatc tacaatcaac cactagttca
    21181 aaacaataaa gaaatgaagg aaacaccatt taaaatagaa aagcaaactg gtaaatctat
    21241 ttatactgta agtatatact ataatgaatc ggtgcaagaa agtcataaaa atagcaattt
    21301 aaataacaaa acttatacat ttgatgttat gtcaagaata gggtaataag aatttattaa
    21361 aaaataagta ggttgataaa atatgagtaa aaagaatagt gaaagaggat tttccttaat
    21421 tgaagtgtta gtagctatgg ctattatggg aattgtacta tttgcatttt ttaatattat
    21481 caatactaat aacaaagcaa acactaaaaa tgacacagat ataacttcct taaactatgt
    21541 ccaaagtgaa atagaaaatc taagagaaaa gataaaaagt ggagaatttg attttgatag
    21601 tttagataaa ctagaagatg gaactgtcgt atatgaaaaa ttaatagata aatcaaaaaa
    21661 agttgtatat gataaagttc ttagtgaagg tgacgtgagc ttatatgata ctccatatga
    21721 aaagattaca acaataaaag atgaagatgg taacttaatc gacaaaggaa atattacaaa
    21781 taagataaag actattgtag aagataaaag tggtcagata tataaaatag ctgtaactgg
    21841 gaaaagcatg aatgactatt caagtaaaaa agaggttaaa attgtaactg aaatatttaa
    21901 agataaataa ttttacttgg gggtgagatt ttgaggaagt ggaataaatt taaaagtgaa
    21961 agaggggcag ctttagtttt agttttggtt gtagtagcat tgctttctat tgttggattg
    22021 atattttcaa atcagatagc taatagaata aaatctacaa agactactaa tgaaggtata
    22081 caagcaaagt atttagcaga gacatgtgtg gaaaatagta ttgataaagc atatgaaaaa
    22141 ttgtatgatg agcttgagaa aatggataat gagtttaaaa gtgaaaatca agaaaaatcc
    22201 atatctaggt caaaattaag aaatatatca gatgaagatt ttaataatca agatgaggaa
    22261 aatattgaag cagaaagact tggatatatg aataatataa atttctattt aaataaagct
    22321 tcttcagact tggaaaaagc tagtatggaa ttgaaaaagc tatatgattt agatatgttg
    22381 gactatagag acattgaata tgtagatgca aatattattt cacatagaga ttctatctta
    22441 gaaatttgca agaattatac ttctggagat attagtaaaa taaatgaata tattctgaaa
    22501 gaagatatag actcaactac attgattgag gcaaagttag tgaataatga tattcttttg
    22561 aaaatgtttt tagaagaaaa taaaattgaa aatgaacatt taaattcagc cttttcacat
    22621 acttataagg cattagataa catttctttg gcgatgcaaa atatgattga gtatagacat
    22681 acgtttcata tagatgagcc aaaagtagaa gtatctaatg ggattccaga ctctcaacaa
    22741 tattatgaac taatacaaaa tcctataata aatagtatgg agtatagctg gaatagtaaa
    22801 tgggatacat tagaaaacct attggaaatt ttaccaaatc aaactcaagg atttaattct
    22861 ttaagagttc atttgagaaa taatgtaaga aaatttgaga agttaagcga taatatatct
    22921 agtggtaaaa aaaatacagc aaaaaatttc ttaaagtata aagagttatt gtatgaaata
    22981 tcagaccaat gtaatcaact aaaaagtatg tcttatgaga aaatacctgt taaatatgat
    23041 aacatggctt tgataacaac ttttgactat atacaaaatg agcttttagc agagataaaa
    23101 tgcagattaa aagaattaaa accacaagaa attgataaaa cagaaggtat tactataaaa
    23161 ataccttttt ataaggctga ctacgacatg acaaaagaag gatggcctaa attaaaagaa
    23221 aatggttcag gggcggagtt aagcttaatg gtaactggtg ataaaaatgg aataaaagaa
    23281 gtagaagtta cagatggtaa aaaaaatatt attggtttag gtgttgaaga aaattcaaat
    23341 tcaaagtata aggttgacgc cattgtaaac tttaatctaa atatagatac aaatgtagtt
    23401 ggaaattatg atataaaaga taaaattttg attaatcatg atataagttc atacaaaaaa
    23461 gtaaactaaa tataagaagc aacttagtat aaataacaaa ataattttat tatttactac
    23521 taaaaaaata agtaaactaa tagaagatat ggagagtaaa tattatgtat atttatgatt
    23581 tattagagca aggtataaga ctaaacgcat cagatataca cataacagtt ggaacaaatc
    23641 ctgtagctag agtaaaaggt ggatttgtaa aactaagtga acaaatattg acatcagaag
    23701 taacaatgca aatggcaaaa gacatagcag gggaatctat gtttaaagta atagaagaac
    23761 atggagaagc tgatttttca gcttctctaa aaacaggaga aagatttagg gtaaatgcat
    23821 ataggcaaaa aggaaattac gcaatagcaa taaggactat aacagcagaa attccaacat
    23881 ttgaaaaatt aggccttcca gagagtataa aatcttttac tgaaaagcat aaaggattag
    23941 ttttagttac aggtccaaca ggaagtggta aaagtacaac acttgcaagt atgataaata
    24001 taataaatga aaaacaacaa aaacatataa ttacacttga agacccgata gaatatgtac
    24061 atcatcataa acaaagttta gtaaatcaaa gagaagtagg aactgataca gaaagttttc
    24121 attcagccct tagagctatt ttacgtcagg acccagatgt aatactaata ggagagatga
    24181 gagaccctga aactgtttca atagcattaa cagcagcaga aacaggtcat ttagtatttt
    24241 caacactaca tacagtaggg gcagctaaga caattgatag aatagtagac atgtttcaac
    24301 catcccaaca gcaacaaata aaaacacagt tatctacagt ttgtgaaggt gtggtatcac
    24361 agcagttact tcctacagca gatgggaaag gcagaatagc agcaattgaa ttgatgtttg
    24421 ctactccagc aataaaaaac ctgataaggg aaggcaaaac atatcaaatt ccaaacatga
    24481 tacaaactgg agttaaatca ggtatgaaaa ctatggacca agatttaatg gaactttata
    24541 aaaatggaaa gattacaaaa gatatggcac ttagtaggtg tactgaccaa gagtttatga
    24601 caagaatgat aggtggagta aactacaatg gatattataa tcgttaatct atatgtattt
    24661 atagtgggta tagtgtttgg aagtttcttt aacgtctgta tttttaggat tccagaaggt
    24721 atatctattt ctagacctcc ttcccattgt atgagttgta atactagact aaagccaata
    24781 gacttaatac cagtgctaag ctatttaatg agtggcagaa agtgtagata ttgttatgag
    24841 aaaatttcta gtagatatgc tatagtggaa ttaattacag gaattttatt tttaacagta
    24901 tttatgttat atggaatatc tacatcaact atttattatt tggttcttgt gtctttactg
    24961 attataatta catttataga tattgaccac tttataatac cagataaaat attggttttt
    25021 ggagctatat tttctatgat ttttaacctt ttatttaaag aaattccagt taaggattca
    25081 attctaggtg tttttatttg tggaggaagt gtctggatta tagttctttt gattgaattt
    25141 gtaataaaaa aagagtgtat gggtggagga gatatcaaac tatttgcaat gctaggcctt
    25201 tacatgggtg ttaaaaatgg tcttttgaca gccttactaa gcgtttatgt aggagcagtc
    25261 tatggaatct gtgtaataat tataagtaga ataaaaggaa aggaatataa ttctgttata
    25321 ccatatggac cttttatatc tattggagca ttaataacaa tcttatgtgg aaagcaatta
    25381 cttgaacttt atttttctat ggttatatag atgatagtca agttaaataa agttttaatt
    25441 taaaaaaatg aattaaagta tttaataagg acaatattat tattaaccct attactaaag
    25501 tgctacaaac tatggagtat ataataataa tttccttatt ttttgcacat ttgataaata
    25561 aatctctatg tgttttttgt gatagagaaa agaaaaattt atacaatacg ttttttattt
    25621 acataataac tgtagtttta tctgtattaa tatatctaaa atttgggatt agtgtagaat
    25681 gtgtacaata tatggtttta attccatttt taataattat atccattgta gattactaca
    25741 caatatatgt atatgatata acaatagtta gtggtataat agttcaaggt ataatttttt
    25801 tggtcttttt caatatagtt caatttgatt atataaatca tatatttgga ctattgatag
    25861 gctttattat accttatatt attgctaaac taacaaaagg attaggctat ggagatgtag
    25921 gtctctatag cttatgttgc tttgcattgg gaaataatta tgggttttat gtgatagttt
    25981 tatcatttat tttagcgttt ttgtttttta ttattttata cataactaaa atatttaaag
    26041 atgtagatat aagaaagcaa attcctttta caccttttat ttccttgtca acaattttaa
    26101 taatatttac agagtataat atatttaatt tttattataa tttgttatac aaatttatat
    26161 aacaggaggt aagaaatgta cgtagtagta gggttaggta atccaggaaa gaagtatgag
    26221 aagactagac ataacgttgg atttgatgtt atagatattc ttgctaaaga atacaatatt
    26281 agtgttacta aaataaagca taaagctttg attggtgaag ggagagtagg tactgaaaaa
    26341 gtattattag ttaaaccaca aacttatatg aatttaagtg gagaaacatt aatagatata
    26401 tataaatatt ataaggttga tttaagtaat atagtagtag tatatgatga tatagattta
    26461 gaagttggaa agatacgtat aagaaaaaaa ggaagtggag gaactcataa tggcatgaaa
    26521 tctataacta agtgcctagg ttcaaatgac tttccaagag tgagagtagg tgtatctaaa
    26581 ccagaagctg gtcaagactt agcagacttt gtactttcta gatttagaaa agaagaatct
    26641 gataacataa atgaagcatt agaaaaagcg gcagatgcta ttgactcaat aataagagaa
    26701 aatatagata tgtctatgaa caaatataat ggatagtgag agggagattt aaatgaatga
    26761 tgttttttta tatcctttgc aaaattcaaa agagtataaa gatataataa actgtataaa
    26821 aaatacaaaa ggctcattat tggttaatgg acttttacca gtacaaaaac ctcatatatc
    26881 gtattctata tttaatgatt tatcacgaca aatgattttt ataacgagta gtgatttaga
    26941 agcaaagaaa gtatacgaag atttaagttt ttatatggaa gataaagttg aatatttagg
    27001 ttttcaagat atttattttt atcacttgga tgcaaaggac agaaacgaag aagcgaagaa
    27061 attaaaagta ttgttaaaac tagcaaataa agaaaaaatc attttagtaa cttctattga
    27121 ggcagtttta agaaaataca taccaaaaca agttttgctc gatagtgtat ctcattataa
    27181 ggtgggagat agcttagact tagaaaagtt aactgagaaa ttagtttcat tgggatatga
    27241 aagagtttca aaaatagagg ggtttggtca atttagtata agaggtggaa ttattgatgt
    27301 attttcactt gaatatacaa atccaattcg tatggaatta tttgatgatg agatagattc
    27361 catacgaact tttgacgtat attcacaaaa atcaattgat aaattgcaac aattctctat
    27421 aactccatct agggaattta tttatcccga aaaaactaca gatgcattag ttaaattaaa
    27481 aaaagaaaca actaaaaata ctgatgaagg tacatttcaa aatatagatt atatatcaag
    27541 taagacttat tttgaaggtg tagagaacta tatagattat atttatccag aagaaaacaa
    27601 aagtatattt acttatttag cagatgatgc aatagtattt attaatgata taacgagact
    27661 taaagaaaga tgcgaaaatt atataaatga gtttagagaa aattataaat taaatcttga
    27721 aagaggtctg gctattaaaa accaaggtaa attgttatat cactatacag atttagagta
    27781 cttagtaaaa gacaagtctg tggtattaaa ctcgctattg ccaaagtcta taaataactt
    27841 ttctataaaa tctataataa attttgaaag tagagaagtt cctacattta atggaaaggt
    27901 agatttgctt gtagaagaat taaatcggct gaaatataat ggatacaaaa taattttagc
    27961 aacaaatacc ttagaaagag caaataaatt aggaaaagat ttattggaca aaggcttaga
    28021 aacgaccatt tctaaagata gagatattga aattaaatct tcacaagtta taattgtacc
    28081 tgcacacata aacagtggtt ttcagtataa atctataaag tttgttgtta taacagataa
    28141 cgaaatgata ggtgtttata aaagagcgtc taagactagc aataaaaaag ttaaaaaggg
    28201 aaagaaaata gaatcctttt tagatttaag tgttggagac tatgtagtcc atgaaaatag
    28261 tggtgtaggt agatacacag gaattgaaca aattacagtc aatgctatta aaaaagatta
    28321 tatgaaaata gtatatcaag gtggagataa tctatatgtg ccaatagacc agatggacaa
    28381 agtacaaaaa tatattggtg cagaagtaga aaaagttaag ttaaataagc ttggaacaaa
    28441 tgagtggacg aaagcaaaag caaaagttaa aaaagaaatt gaagatatga caaaagactt
    28501 gattgagctt tatgcaaaac gtgaaaaaat acaagggtat aagttttcaa aagatacacc
    28561 ttggcaggca gagtttgaat cgttgtttcc atatcaagaa acagaagacc aattaaaggc
    28621 tatagaagaa actaaaaaag atatggaatc aagtaaggta atggataggc tagtatgtgg
    28681 agatgttggt tatggaaaaa cagaggtagc tattagaagt atttttaaag cttgtatgga
    28741 ccaaaaacaa gttgctgtat tggttccaac aacaatattg gcccaacaac attataatac
    28801 attcaaagag aggtttgaaa attatccttt gagagtagaa gttttaagta ggtttaaaac
    28861 accaaaacaa caaaaacaga ttattgaaga tgctaaaaaa ggattagtag atattttaat
    28921 tggaacacat agaataatat ccaaagatat aaatttacca aacttaggtc ttgtagtcat
    28981 tgatgaagaa caaagatttg gagtaaaaca taaagaagct ttaaagaaaa ttaaatctac
    29041 agtagatgta cttacacttt cagcaactcc tataccaaga acattacata tgtctttaag
    29101 tggaataaga gacatgagtg ttatagaaga acctccacaa gaaagacatc ctgtaataac
    29161 atatgttaca gagagtaagg aaagcgtaat tcaagatgag atagagagag aattaagtag
    29221 aggtggacag gtattttttg tatacaatag agttgaacac attgaagaaa tggcaagtat
    29281 gattcaaaaa ctcgtaccag atgctagagt ggctgttgca catggaagaa tgacttctaa
    29341 atcattagaa aatataatcc taggattttt aaataaagat tatgatgtac tagtctgtac
    29401 tacaataatt gaaactggta tggacatatc aaatgcaaat acaatgatta tatatgatgc
    29461 agataaaatg ggattggctc aactttacca attgagaggt agggttggaa gaagttcaag
    29521 acaaggatat gcatatcttt tgtatgaaaa agataaaact ttaagtgaga tagcggagaa
    29581 gagattaaaa gctatcagag aatttacaga gtttggttct ggttttaaaa tagcaatgag
    29641 agaccttgaa ataagaggag caggaaatat tttaggttct caacaacatg gtcatatggc
    29701 agttataggt tatgatttgt acgttaaaat gcttaatgat gcaattaaaa aagtcaaagg
    29761 tgaacctatt gtggaggaaa ttgatgttga aatagattta agtgtaaatg catacattcc
    29821 agataattat atcaaagatg agttgattaa aattgaaatg tataagaaaa tagcttctat
    29881 tgaaaacaaa gaagacatgt tggatataca agaagaactt gaggatagat tctctgatat
    29941 acctaaacca gtccagacac ttcttacaat agcttatata aaatcgttat gtaagatatt
    30001 aaaaatagaa aagataagac aattaaaaga tgaaatatta ttagttccaa taacaaagta
    30061 tagaactaaa cagaaaatag gttataatat agttacagaa ttagaagaat tattagaaaa
    30121 gatgtgcaag gtaaaataac ttgtaaattt aagaagggat gttttaaatt tgaaaaaagt
    30181 aataacattg gtaatagcta tgattttggt agtatctgtg actgcttgca gttctagtaa
    30241 aggagaaact gtggcaacag ttgaaggtac aaagatatca tcagatgaat ttaaaaaaac
    30301 tatagctctt tataaagatt ctatggaaca aacttatggg aaagatatat gggataagga
    30361 agttgaaaag ggtgtaaaat acaaggacaa gtttaaagat ttaattcttg accaacttat
    30421 aactacagaa gtaatatatt ctcaagctaa aaaagataac ttacttccta aaaaagagga
    30481 tgttgaaaaa agctttaaag aattaaaaga cgctatgggt aaagatgaaa aatataaaga
    30541 acaacttaag aaattaggta tagatgatga gtttttaaga gaccaacaag agaaagattt
    30601 agcaatgcaa aactatcaaa gtaactttgc taaaaagact aaaatatcag atgaagaaat
    30661 gaaaaaatac tatgatacac ataaagatga atttaaaaaa gatgaggtag aagcttctca
    30721 tattttattg aaaacagtag atgataataa caagccactt tcagataagg aaaaagctga
    30781 agctaagaaa aaggctgaag aggctcttaa agaagttaaa tcaggtgagg attttgcaaa
    30841 agtagcaaaa aaatattcac aagatacttc agcaagtgat ggtggtaaat taggattctt
    30901 ttcaaggggt caaatggttg ctgaatttga agatgctgct ttttctatga aaaagggtga
    30961 agtatctgat ttagttgaaa ctcaatatgg ataccacata attaaagtga cagacagaat
    31021 aaatgagcaa acatcatttg aagatgctaa agaaactata aaagaccaac tgttgaaaaa
    31081 taaatatcaa gaacaaatag aaaaattaac taaagaagct aaggtagaaa aagatgaaaa
    31141 agtaataaat aaaatcacaa tctaagactt aaaaaaagag taatatgctt aaaaaagcta
    31201 tatctggata agatatagct ttttttgtat atttttctta acaatggtaa aaataaactt
    31261 aaagtaattt atggagggat taaaaaatat gaaagcaaca ggtatagtta gaagaataga
    31321 tgatcttgga agggtagtta tcccaaaaga gataagaaag acattaagaa ttagagaagg
    31381 agacccttta gagatattca cagcaaaaga tggagaagtc atacttaaaa aatactctcc
    31441 aataggtgaa ttaaatgaat tttcgcaaga atatgctgaa acattagctg aagtactagg
    31501 atatggagtg ttgataacag acttagattc tataatagct gtgtctaagc ttcctaaaaa
    31561 agattataaa gaaaaaagta taagtgatga gttagaagca ataataagtg aaagaacagt
    31621 aaaatattca aaagataaaa acattttacc attattcaag gaagaccaaa aagaatatac
    31681 tagtcaagtt atcatgccta taattagtgc atctggtgac tgtataggtt caattgtagt
    31741 tgtttcaaag gataaagata caattgcaga aagtgaagaa aaatctttaa aaattgctgc
    31801 taacttttta ggaaaacaag ttcaataatt ttatcataaa gaccttttac atgaaggtct
    31861 tttgaagttt ttgtgtaaaa tattgaatat agcattaaaa atatggtata ttaaagtttg
    31921 ttatataaac agtatggagg ttatgttatg aacaataaca aaaataaaga ctcctttcta
    31981 aaaggagccc ttatacttgg gctagcaggt gtaatcgtaa aaataatggg tggatttttt
    32041 aggattcccc ttggaaacat gattggttca gaaggaatgg gatactatca ggctgcttat
    32101 cctgtgtata ctctattttt aacattagct actgctggat ttccaacagc tgtggcaaaa
    32161 ttggtttcgg aaaaagttgc aattggaaat tttaaaggtg caaataagat atttaaggta
    32221 tcacatacag ttttattcat taccggtata atatcatttt gtatattatt ttttggagcc
    32281 gactacatag taacaaacgt aatgaaaaat ccaggtgcgt tatactctat gaaagccatt
    32341 gctccagcat tactatttgt tcctgcaatg tctgcatata gaggatattt tcaagggaga
    32401 caagatatga ctaagattgc tgtgtctcaa gttgcagagc aattttttag agttgtatta
    32461 ggtcttactt tggcctactt gcttatgaag agtctaggtc agacttttgg tgcagcaggt
    32521 gctatatcag gggctacaat aggttcaata gcatctatgc tttatttggt gtttgcttat
    32581 atgctaggga gaaaagagcg tagagcagag atagatgcaa gccaaagatt taaagatgaa
    32641 agagtgtctt atatttttaa aaagctttta actgttgcca ttcctataac aataggagca
    32701 tcagtaatgc cacttgtaaa tatgatagat aatgttattg taataagaag acttatggaa
    32761 gcaggcttta catacaaagt ggcaaattca atgtttggtc aattaacagg tatggcaatg
    32821 gccacaataa atttaccagc agtcataaca actgcaatga gtatgagctt agttccagca
    32881 atttctaaag catatgcatt aggaaataag tcaaaagcta gaaaagatac taagagtgca
    32941 gttaaggtaa ctttacttat agtattgcct tgtgcgtttg gtatggcttc tttagcaata
    33001 ccaataatgg gtcttttatt tccacatgaa ccatcttctg taggaactat tttgtttact
    33061 cttactccat gtgtattatt tttaggatta atacagacat tgactggtat aattcaggga
    33121 atgggaaaac caatagtacc tgtaattgct ttatgtgttg gtatgctatg taaaattgta
    33181 ataagttata ctttaacagg tataccagat attaatgtac tgggttcagc atttggtaca
    33241 gttacagcat actttgtggc agccatgatt aacttactat atgttaaaaa acacatgaat
    33301 gtaaactttt ctaaaaaaga atttataata aagccattta taacagttat gacaatgttt
    33361 ataatggtta agttgagtta tggtgcttta gttggattct taggaaacag catatctaca
    33421 ataattgcaa tatgtgttgg tggaattgta tatgtagtag taatacttgg aataggtgga
    33481 attaaaaaag aagagattct aactatgcca aaaggtgata aattatataa attgttaaaa
    33541 aaagttaaac ttataagata atataggaat atatatgcaa ataaaggaaa tactatacaa
    33601 atagtaaatc tccttatttg tataataata taaaaataaa gtgaaatttg ctaataggag
    33661 tgatgttatg ggtaagataa gtattgtagg tcttggacca ggagactatt ctcttataag
    33721 ccaaggtgtg ttagaatctt taataaatag ccctaaagtt ttttttagaa cagagaaaca
    33781 tccaataatt gataaactta aagaaactat acaatacact tctttagact acttttatga
    33841 aaaagaggaa agttttgata atgtttattt gaaaatatct gaatttatca tagaagaatc
    33901 agcaaagggt gacctagtgt atgctgttcc tggtcaccca agagttgcag agaagactgt
    33961 aagtataata gagagattag ccaatgaaaa gcacatagca gtagaaatat tgccttctat
    34021 gagctttgta gacgctatgt ttaactattt ggctatagac ccatctgagg gatttaaact
    34081 ggtagatgct tttgaaatag aaaattcata tatagacttg gatacaagta tgataataac
    34141 tcaggtatat gataaattta tagcatctaa tgtaaagtta aaacttatgg aacattatga
    34201 ctataatcaa gaagtatgta tagtaaatgg agcaggtgtc aaagatttag aaagtaaaaa
    34261 gtttataaag ctttgtgaat tagacagaaa tgaaaacttt tttgactatt taactagctt
    34321 atatataccc aaaagttcta aaaagatgta taatacagta catgacttag aaataatagt
    34381 taatacactt agaagtccat ctggatgtga atgggataaa aaacaaacac atcaatcatt
    34441 aaaaaattct gttatagagg aagcatatga actttgtaat gcaattgata ataatgatat
    34501 agatgaaatg gtagaagagt taggtgatgt tcttttacag gttatattcc attgtcagat
    34561 aggaaatgag gagggctact ttgatttaaa agaagtagta aatggcatat gtaaaaaatt
    34621 aattcataga catcctcata tatttagtgg tgcaaaatta gatatgtcta agtttgagaa
    34681 aacttgggaa gaattaaaga aagaagagaa aggcgaaagt actataacag atggccttag
    34741 aaggatacca aaacatttac cagctcttat gaaggctagt aaagttcaac ataaagcagc
    34801 acttgtcggc tttgattggg acaatgtaga agatgtattt aaaaaaattg aagaagaata
    34861 tcaggaatta cttgacgaac acagggtcgg gaatataaaa tacataaagg aagagctagg
    34921 cgatttatta ttttcgatag taaatctagc tagattttta gacatagact caggagaagc
    34981 cttgaactgt actacagaaa aattcataaa tagatttgac tttatagaaa aaagtgcaat
    35041 gaacttgaat aaaaaattag aagacatgac acttgaagag atggatgagt tttggaatca
    35101 ggctaaaaaa caataaaatt gtggaaggaa atttgtcaaa aatctagaac ttttatcaca
    35161 aagatagaag tctatattat aaacattttt aggaggtaaa tatcgtgaat aaagctgaat
    35221 tagtatcaaa gatggcagaa aaaagtggat taacaaagaa ggaagcagaa gctgcgttaa
    35281 acgcatttat gagttctgtt caagatgcac tagtaaataa tgaaaaagtt caattagttg
    35341 gatttggaac atttgagaca agagaaagag ctgctagaca aggaagaaat ccaagagatc
    35401 cagagcaagt tatagatata ccagcttcta aagcaccagt tttcaaagct ggaaaaggat
    35461 taaaggatat aataaatgga taattagaaa tcttgtgaaa aagtgtggat aaatttgcca
    35521 cactttttct atagaaccaa ggaaggtgat aattatgaga ttagataaat ttttaaaagt
    35581 atctaggatt ataaaaagaa gaactgttgc taaagatgca tgtgataaag ggattgtcac
    35641 tataaatgga aaagttgcta aatcttcttc agaggtgaat attggagata cattagaaat
    35701 acaatttgga gagaagaaga tgaagtttaa gataaatgaa gtaaaagagc atgtattaaa
    35761 aaatgatgca aaagaaatgt acgaaatttt agaataaaat taatagtcct ctagtatatt
    35821 aatagtagta ttattgaaat atttactggg gggatattat ggaacagaac ataactttga
    35881 aagatagatc aaagctggtt atttcgggag tcgagcacat atactctttt aatgacaaaa
    35941 gagtagagct caaaacttct gtaggcgaga tggtaattga aggcgaaaac ctagatatga
    36001 gcaagctaag tatagacgaa aatataatta gcatagatgg aactataaat tctatggtat
    36061 atgcaaagcc taaaaagcca caagagagtt tcttgaaaaa ggtatttaga tagatgatac
    36121 cttttactca agatgtaagc attttttatg ctactattta tggtggaata ctcatagggg
    36181 tgttgtttga tttttataga gggctaagag ggaattttaa attcatcaat tattttgcta
    36241 taatctttga tgtattgttt tggtttctag ctacggttat aatattcgta acaataaacc
    36301 ttacagaatt ttttgattta agatattatc attttgtggc tttgtttatt ggttttattt
    36361 tatactataa caccataagt aaaattgttt tatcaattat caataaaata atttgttttg
    36421 tgagaaattc ttttaaaaaa gttacacatt acatagtcag ttttttaaat aatttgtatt
    36481 acgttataat ctattcacta cacctactat ttgatattat attttatata ccaaacatat
    36541 ttatagcaac aagaaaaagt ataaaaagaa aatcaaataa aaaattaaag aacaagaaaa
    36601 aatcaaaacc taagaagaaa aaaaataaaa ctaaaaaaag ggtgtaggaa aaatgaactt
    36661 aagaaaaaaa ttttcaggac agattattgt tatcagttta tttttaggaa tatcaatttt
    36721 tagtatgatg acaggatttg tatttgagta tacaaaagct aaggaatata aaaaagaaat
    36781 agcaagtcta aataaacaat taaaaaagac tgaaatacaa ataaacagct taaagaaaga
    36841 tgaaaaatca tatgaaggag acttagagga tatagcaaga aaaagattga atatggtaaa
    36901 accaaatgaa acagtttatg tagacataaa tcgttgatta aaacttgcta ataagtttac
    36961 agatgtattg attttaaaat ttaagattta ataaaaaagt cattcagtta aggatggctt
    37021 tttgttttta ttgaggaggg aatttcataa tgaaagtagg agctatagat attgggacaa
    37081 actcaatgag attactgata gcagattata gagatgggaa ttttataaac agaaaaaaat
    37141 ttgttaatac aactagaatt ggttatggtg tggatagtaa aggatatata aaagaagatg
    37201 ctatcaaaag aaatataaaa gcattaaaag aattttctga taagtgtaat gatgaaaagt
    37261 gtgaaaaaat ttattgtatg gggacatctg ctcttagaga cagtaaaaat ggagattact
    37321 ttgttaaatt agctaaagaa gaaactggaa tagatgttga tatagttacg ggaatagaag
    37381 aatcaaattt gggctttaag ggtgttttag aaggaataca aggtgatgat actattattg
    37441 ttatagatat tggaggaggt tcaacagaat ttattgtagg tgattcagaa ggaattaaat
    37501 ttaataaaag tgagaatgta ggtgctctta ggatgacaga gaggtttttg aagcacgata
    37561 ttattgaaga tgaagagttt gaagctatga gttcatttat atatgatgag attgacaaaa
    37621 cgttaaatca tataaaagac agaggattaa aaactcttat aggtatagga ggtacgatta
    37681 catcattatc agcaatgaat caagaattag agatttactc tatggaaaaa atacataata
    37741 gtaaaataca caaaaaagaa atagaagaaa ttctacaaaa attaataaag atgacattaa
    37801 gtgataaaaa gaacttaaaa gggctacaag aaaaacgtgc ggatattata actgctggtg
    37861 taaaaatatt gaatataata atggaaaaat tagaaataga agaaataacc gtaagtgaat
    37921 acgataattt ggaaggctta atatgtcaaa agtcaaaaaa aatgtattaa tattttttga
    37981 tttttaaaac cgattatgac aaaaaaaatt actcctcttt gttacaattc ttaatataaa
    38041 caaaagagga ggttttttta tgcaaagaag tgtagcagtt gtgaagaata agactgtaaa
    38101 accaaatgtc ataaaattaa taagcggata tattgatttt actacggcgg cattcgctgt
    38161 gatgggattt ttacttagta ggtctattat agtagactct gtagctcctt taggaattgc
    38221 cttttttata tgtgcatcaa agattgataa gtacaagata cctgtattca tatcaacatt
    38281 attaggaata ttgttatcat ctaatgattt tggaaatgta gcaaaatatg ctgtgtgcct
    38341 tacaatattt atggctatga ataaaaaatt aaaattatca gattcaattg ctaaggttgc
    38401 atttataggt gcaataatac tacttccaat ctccatggga caagctttct tttcaaatag
    38461 gtatgtatat ggtcttctta tagcaggagt agaagcaata ataatgttta tatctatata
    38521 tgtgttttct tatgggatag gtttaatggc caatgtcaac aataggatgt ctgtacggac
    38581 agaagaagcc atatcaataa gtttactgct aacctttagc ataatgggaa taggagatat
    38641 atctctgttt ggaatatcaa taaggaccat tttatcgacc gtattgatat tgctgacctc
    38701 aatagtaggt ggagctacca tgggagcatc tagtggtgta attattggtg tagcatccat
    38761 tttaaataat atgacatcag ctgtttatat ggggatatat tctttttcag gactaataag
    38821 tggagcattt aataaaataa ataaatattt ctgtatacta ggatatattc taagttggac
    38881 aataatatac ctatatactt ctggtattac ttctaatatg atgcaattaa gagatatact
    38941 attaggttgt ttgatagtac tagtattgcc agagcgatta tttaataaga ttgaaaaatt
    39001 aataaaaagt aatgtggctt caaatgaaat cgtatacgat tatattatga gaagcaaaaa
    39061 cctaactaat agcagattga acagtattta taaaacttat gatgaccttg cagatacatt
    39121 tgataagata agagaaaaag acaaagtgct agaccaaaga gacatagcta atgtaataga
    39181 tatgattcat aatgatgaat gtaaaagttg tagtatgaga agaatgtgct gggagtcaag
    39241 atttaatcat acatacacta tgatatataa cattcttgaa aaaattgagg agaaagggga
    39301 gttaagtcta aacgatatac ctaaaaattt tagaaaggaa tgtatgaaac cagagtcaat
    39361 agtgaaaata tcaaatcact attacaaaat gtttgtatta gattatgatt ggagtgtgaa
    39421 gttttcagaa agtagaaagt taatagcaaa tcagataaga agtatttcaa aatccattaa
    39481 atccttatct caagatttag aaggcgacat aatgctagat atagaaaagg aaaaaaatat
    39541 atatgaacag ttagaaagat atgatataac agttgataaa gtaagttact taacaaaaag
    39601 taacagtgag tttgaaatat caatagaaaa gaaaacttgc catgatggat gtatgtgtga
    39661 agataaaatt gtaaatataa tttcagacct agtaggggaa aatatgtctg ttagaaaaat
    39721 aggatgtcac tgtttaggag gtaaatgcaa ggcaacattc gttaaatctc aaaaatataa
    39781 ggctgttaca gaagtttcag caatgtcaag ggatgggcat atcctttgtg gagacaatta
    39841 cacatacatg gagataaatg atggtaaata catgatggct ataagtgatg gtatgggaaa
    39901 aggtaaaaaa gcatatgaag aatcttctgc cactattgat atactggaaa aaatgataga
    39961 tgcaaaaatt aaagatgaga tagtcattga tactataaat aatatgttgt tgttaaaatc
    40021 ttcagaagag atgttttcaa ctctggattt gggaatttta gatttaaaac gaggttgttt
    40081 agaaactata aagatgggag cgtgttctac ttatataaaa agagaggatg gagaagttga
    40141 cttaatatca tcatcatcat tacctgtggg tatattatca gatgtaaaaa ttgatagaaa
    40201 aaatgtaaaa gttaaggaag gagactatgt tataatggtt tctgatggaa ttgtagatgc
    40261 aggaagaaat aacaatttag gagacaattg gttaatatac ttcttaaaga atatagagac
    40321 tacaaatcca aaggaaattt caaatttaat attggataga gcattagagt tacaagcgtt
    40381 acaaatcgaa gatgacatga ctgttttagt tacgaaaata tgtacaaaat aaggtttaca
    40441 agattatgtg tataagatgt ggataacttg tgtataatat gttaatagac ttttgaaaaa
    40501 agtatagtta ttaacaaaaa taacatataa atcaacaaaa tttgttgata agtatggcag
    40561 aaatgttaat aaaatgtaaa aaaagaaaaa acaaaagcta ttatcaaaag agactcatgt
    40621 tgaaataact aaatttctaa gtaaagaaaa cctgtgaata tgttgattat tatgtggata
    40681 actattaatt cgatatttat ttatatagta tgaataattg aataatatat ctaaaaaaag
    40741 ccatcctatt attaagtaaa cttattgaaa ggatggcttt ttatgaatag aaaattgtgc
    40801 aaagcaataa tacctttatt tatttctatt ttttgcatgt taataataag tataaaagct
    40861 gaccaaggat atcaaaagaa taatgacaga gcaattactg tcatgaataa taatgatact
    40921 gaagatgatg ctgaaaaaaa acaagaaata gactatgaaa aaacatgttg gaatttgcaa
    40981 tctttgttta aaagtgatga ccaatggaaa aaagaactta agagttttga taaagatact
    41041 aaagagttga aaaattacat aggtaaagta acaaaatcgc caacacattt gtcttttgcc
    41101 ttaaacatta aagaaaaact tgatataaga ctaaataaac tttctgccta tgtaaaatta
    41161 aaacaagata ctaataaaaa ttcgtataag tacttagata tgaatgatag tatgagtaaa
    41221 tcctatggga attatatggg gatttgttca gatttagagt tagaaatact aaaattatca
    41281 aacaaagatt acaagaaaat tatttcaaat aaaaatataa ataggaaata tggtgcatat
    41341 ttaagagata taagaaggaa taaagtacat tatttggatg ataaatcaga agatattcta
    41401 agcaaagtat cttcaataag tagtcttcca agccaagtgt atgaattatt tagaaatatg
    41461 gatagaaaaa ctaatttgac accagctcaa tatgcgagtg aattagagtc atcagataga
    41521 gaaaatagaa aaaaagctta tcaagatgaa cttataactt acaatgataa tataaataca
    41581 attgcaggtt taattactgg tcaagttaaa aagaatattt tttattctca ggaaagaggt
    41641 tatgagtctt ctttagaaat gtacctggaa tctgataatg tagatgaaaa agtatacaat
    41701 aatttgataa ggactgtaaa tagtaatatg gacagtctgc acaaatatat agatttaaga
    41761 aaaaaagtat taaaattaga taaggttcat tcatatgata tgtttgtgcc tatggttaag
    41821 gctgttgata ataatattaa ttatgaaaag gcacaaagta tagtatattc agcgttgtca
    41881 cctttaggaa aagaatacaa tgatgtagta tataaagctt tcaatgaaaa atggatagat
    41941 gtttattcac atgaaaataa agtaagtggt ggatactgct tatctgttta tgaaaatcat
    42001 ccatatatac ttttaaatta taataattca ttaggttcag tttcgacttt atcacatgag
    42061 cttggacatg ctgtatatga atatttaagt tctaagaatc agaattattt taattcaaat
    42121 ccgtctatat ttactcacga agttgcatct acaacgaatg aagcattact ttacgagatg
    42181 cttataaaag aagctaaagg caatgatgaa aaagcttatt atataacaca gtatttagac
    42241 ttgataaaag atactcttta tacacaaact atgtatgctg aatttgaaaa aactatacac
    42301 gagttagtag aaaaaggaaa aagtgtaaac gcattagtat taaatgatgt ttggggacaa
    42361 cttcttaaaa aatattatgg acaaagctat gaattagacc aattatctaa ggtcggatgg
    42421 gctagaatcc cacattttta taatagtttc tatgtctata aatatgctac aggttgtagt
    42481 gcaggagtaa gttttgccca agacatccta aagaatggtt cagataacta tatgagcttt
    42541 cttaaaaagg gaagttcaga ttatccaata aatttgttaa aatcaagtgg cataaattta
    42601 actaatacaa aacccataga aaatacaatc aaaaaatttg atagtttagt agcagaactt
    42661 gaaaagctat tataaacatt attgtaatcc acatggtaaa tatatcgaat taatgataaa
    42721 atatactaaa agtttaaagt cctatcaaga taggactttt tatttattaa ttagtgggag
    42781 atgattctat gcaagttaaa gttaaaaagg ctgtaatacc agcagcaggt ttaggaacta
    42841 gatttttgcc agctacaaag gcacaaccaa aagagatgtt accaatagtt gataagccaa
    42901 ctctacaata cataatagaa gaagctgtgg cctcaggaat agaggaaata ctaataataa
    42961 caggtagaaa taaaaaatct attgaagacc actttgataa atctgtagaa ttggaacttg
    43021 atttagagaa aaaaggtaag aaagaattgt tggaggtagt acaaaacata tctaacatga
    43081 ttaacataca ttatataaga caaaaagagc caaaagggtt gggagatgca atttattgtg
    43141 cgaggcattt tataggtgat gagccgtttg cagtaatgtt aggggatgat attgtagata
    43201 atgatgtacc ttgtctaaaa caactaacag atgcatatga ggaatataga actacaatat
    43261 tgggtgttca aaaggtaaat caagaagata ctaataaata tgggataata gaagcaaaaa
    43321 atatagaagg tagagtttac aaggtaaaag acatggtaga aaagccagag tcaggaaaag
    43381 ctccttcaaa tattgctatt ttaggtagat atataataac tcctgaaatc tttgatattc
    43441 ttaaggattt accaccaggt aaaggtggag aggtacaact tacagatgct ttaaaaatat
    43501 tatctaagaa agaagctatg tatgcataca attttgaagg caagagatat gatgttgggg
    43561 acaagctagg atttttagaa gctactgttg actttgctct aaagaaagaa gaccttaagg
    43621 aagattttat aaaatatttg aaacatgtat gtagtgaatt tgataaaaat aacaatgtgt
    43681 tatacaataa tacagatgaa aaaatagatt taattgaagt caatgaagct agagaacttg
    43741 aaattcaaaa ataattaatg aaaggtgatg tatggtggca aaatcaagtc agaaaagaat
    43801 taatagaata atagctgttg ggattgtggg aattctcgta ataacgagta taacagctgt
    43861 tttgagtatg attgcaacta tgtaataaga taaatgacag cagttgatat acataaatat
    43921 aaaaaccata tataacttga tgtagtcaaa aacttacaat attttagtta tatatggttt
    43981 ttagaattta taaatgtaaa aaaaaatttt tataatagtt gcatatttta aaggaaaata
    44041 ttattataag atataaatat agtgataaat ttataaaaac gtgctaagat tggacttgaa
    44101 atacagtaat atagtaggta ataatgtttt aaattttatt tattgaccat aatatataaa
    44161 taatgatatt attagactta actgtttaaa taaaactttt ctttttcatg ccttcaattt
    44221 ccaaaataag tatgtatata aatgaatata tagatgagga ggattttttt gattttagat
    44281 gataaagtat tagaaggatt aggtagtaag accttagttg agctacgaga gatagctaaa
    44341 gaattaaaaa taaaatcaat tactacatat aagaaaaatg agttaattga gattataaat
    44401 tccaaaagta aaaatgagga aaaagtaaac gaagagacta aagaaaaaaa tgaagatatt
    44461 aaagaagaca taaagaatag aaaagaaaat atagagcgtg aaagtataga aaaagaagtt
    44521 gaatataaga gccctaccaa atcatacaac aagaaagaaa tagataccca aaatatttcc
    44581 caaaaccaag aacatagaaa tcaaagaaat gactataata agacaacgag tgtaaatgat
    44641 agtaataagt catcaaatat atctaataga atggtcagaa ataataataa aaactattat
    44701 atgcctaaac aagttgatga atctaagata gtagatgaat ttaacacatc aaaagaggat
    44761 gaagtagtag gtgtacttga aattctgcca gatggatttg gttttttaag aggttcaaat
    44821 tatttgtcta ctgaaggaga tgtttacgtt tcaccatctc aaataagaag atttaatatg
    44881 aaaacaggag acaagattaa gggaataact agacatccaa aaagtggaga gaaatttaga
    44941 gcacttttat atgttcaaaa aataaatgat gaaaaccctg acacagctat acaaagaaat
    45001 gcgtttgaga cattaacacc aatatttcca gaagaacgac ttacactgga aactaataga
    45061 aatgaaatag ctacaagaat tatagattta atttcaccta taggaaaagg acaaagagga
    45121 ttgatagtag cacctccaaa agctgggaaa acagttcttt taaaaagcgt tgcaaatagc
    45181 atagctaaaa atcatccaaa tgttgaactt atagtactcc ttatagatga aagaccagag
    45241 gaagttactg atatgaaaga atctattgaa ggagacgtta tatattccac ttttgaccaa
    45301 gtatcaagtc atcatgtcaa ggttgcagag atggtgttaa atagagctca aagattagtt
    45361 gaacatggta aagatgtagt aattttacta gatagtataa ctagattggc aagggcatat
    45421 aaccttacaa tatctcctac aggtagaact ttatctggag gtattgaccc tggtgcactt
    45481 catggaccta aaaagttctt tggtgcagca aggaatatta gacagggtgg ttctttgaca
    45541 atattaggaa cagcattggt tgaaactggt tctaggatgg atgatgtaat atttgaggaa
    45601 tttaaaggta caggaaatat ggagctacat ttagatagaa aattagcaga aaaaagaata
    45661 ttccctgcaa tagatattta caagtctggt acaagaagag atgatttatt gcttgatgat
    45721 gaagaaaaga ctgctctttg gagattaaga agagaaatga gtaataattc agtaatggaa
    45781 attacagata aagtcattga acttataaag agaactaagg acaataaaga gtttgtaaaa
    45841 tcaataaaga atttgtaaaa tcaataatac aaatgcaaat atggattata taaactaata
    45901 gaaaaatcac ttgaatggca taataagttg tgctataata atgtagttga taatgtaaaa
    45961 agaaagttaa tataattaat ttttttaaat aaagagaaga ggtgactata atgcaaaagg
    46021 aaatacaacc aaaatacaat ccagttgaag tgcgttgtgc ttgtgggaac acatttgttg
    46081 ctggttcaac taaggacgaa ataaaagttg aaatatgttc agagtgccat ccattctata
    46141 caggaaaaca aaagaacata gaaaaaggtg gaagaatcga caaattcaag aaaagattca
    46201 aaatggacta atttttataa aagtggagtt ggaggaagcc aactcctatt ttattacaaa
    46261 aaaacattca tattctactt taaattgtct ttttgtatta taataataaa tatgtaaaat
    46321 tgagtattct aaatacaata aaatgaggtg agtggatggc aaaacaagct gtaggtgggc
    46381 aagctgttat tgaaggtgta atgatgcagt caaaagacaa aagagcggta gctgttagaa
    46441 aaagtgacgg agaaatagca ctaaaagaag atagaataaa aagttgggta agagataaga
    46501 atatagataa gatacctttt gttagaggtt cttttgttat gatagataca atgattcaag
    46561 gcataaaaag cttaaacttt tcttcagagt tttttatgga agaagctgaa gaggataaat
    46621 ttgatttatt tataaagaaa atttttaaag ataaggcaaa tgatataatt ataatatttt
    46681 cattggtcat agcaatgtta ctttctgctg gattattcat ttttatacct acattggtag
    46741 gaggagcttt ttctaaagta atgcctaatg attttatgct taatttaata gaaggaatca
    46801 taaggatagc tatattattt gcatatatag tattgatttc acgaagtaag gatatagaaa
    46861 gagtctttca atatcatgga gcagaacata aatctatata ttgctatgaa aatgatttag
    46921 aacttacagt agagaatgct agaaaattta aaagattaca tcctagatgt ggtacaaatt
    46981 tcctatttat agttatggct gtatcaataa tattgtttgc attttttggt tggccaaatc
    47041 caattcttag aatatttatg agaattatat gtgtgcctat agtagcaggt ttatcttatg
    47101 aggtaattag agttcttggg aaatatgata atggatttac taaaattatt gcatatccag
    47161 gaatgatgtt gcaatatttt acaacaaaag agcctgatga tgagcaatta gaagttgctt
    47221 tggaagcatt gaaagcagta gtagattaga gaaaaggata tttgttatga cgataaaaga
    47281 tataattatt aaatattcag ataaactaaa agatataagt gatactccaa gattagatac
    47341 agagttattg ttacaaaaaa cattgggtgt tgatagatta tatattcact taaatctgaa
    47401 taaagagcta actgaagaac aaaaaacaaa atttatgggt tttgcagaag aaagattaaa
    47461 tggaagacca atagcatata tagttgaaaa tagggagttt atgggattag atttttttgt
    47521 taaggaaggc gtattgattc caagaccaga tacagaaact ttagtagaag aaataattga
    47581 aatatgtaga gaaaaaaaag atgtaagtat attagatata ggaactggtt ctggagctat
    47641 tacaataagt ttagcaaagt acattgaaaa ttctaaaatc atgtcttttg atatatcaga
    47701 gacagcatta gaaatagcta aaaaaaatgc tattataaat gaagttggtg aaaaaataaa
    47761 gtatattaat tctgatttat ttacagcaat aagtgatagt aacataaaat tcgatatcat
    47821 agtttcaaat ccaccatata ttaaaaaaca agatatagaa actctgcaca aacaagttaa
    47881 agattatgaa ccatataatg ctcttgaagg tggagaagat ggattagact tttatagaag
    47941 aataacagaa caaggtaaga aatatttaaa taagtgtgga atattagcat atgaagttgg
    48001 tcataatcaa gctgaagatg taataaatat tatgaaaagt aatggatata aaaaaatata
    48061 cacaaagaag gatattcaag gcattgatag agttgttata ggttacaata tatgatataa
    48121 tcaacaattg atatgttaca tttaatcgag gtgaaagtat gttaaaaaaa ttagaggtat
    48181 tggaagatac atataaagac ttaagtgaaa aaataggtga tccggatgta ataaatgatc
    48241 aaaaagtttg gcagaaatat ataaaagaac atgctgactt ggaacctatt gttatgaaat
    48301 acagagagta taaaagcgtt ttagatagta taaaagaatc aaaagaaatt ttacaagaag
    48361 agtcagatga agaattaaga gaattagcta aaatggagtt agctgagatg gaagaaaaag
    48421 tagcacctct ggaggaagaa ataaaaatac tattattgcc taaagaccct aatgatgata
    48481 agaacgttat agttgaaatt agaggtggag ctggaggaga tgaagcagct ctatttgctg
    48541 gtgatttatt tagaatgtac tcaaggtatg ctgaaagaag aagatggaaa atagaattat
    48601 tgagtgcaag tgatactgga gttggtggat ataaagaagt atcttttatg ataaaaggta
    48661 aaggtgctta ttcaagatta aagtatgaat ctggagttca tagagttcaa agaataccat
    48721 caactgaatc tggtggaaga atacacacat caacttctac tgttgcagta ttaccagaag
    48781 ttgaagatgt agaggttgaa ataaatccaa atgatttaag aatagatgtt ttccgttctt
    48841 caggtaatgg aggacaaagt gtcaatacta ctgactctgc tgttagggta acacatatac
    48901 ctacaggtga agtagtatct tgtcaagatg gaaaatcaca attaaaaaat aaagagcaag
    48961 ctttaaaaat attaaaagct agactttacg ataaagcatt ggcagaacaa cacaaagata
    49021 tagcagcaga aagaaaaagc caagtcggaa caggagacag gtcagaaaga ataagaacat
    49081 ataatttccc tcaaggtaga ataagtgacc atagaataaa tttaacttta tataagttag
    49141 atgcattctt agatggagat atagatgaaa tgatagatgc tttaattact gttgaccaaa
    49201 cagaaaaaat gactgcaata taagtaatgt tttaaagaag ctgtttcttc ctagaaatta
    49261 ttttctattt tgaaacagct attttgcatt ttaggtcatg ttatcatatt ctattgtata
    49321 taattgttat atacaagtat aggagggtta tatgatacta aaagtaacaa taattgggct
    49381 tttggcaggt gttataggga caggattagg aggagtaata tcagccattt ttaaaagaga
    49441 ggtcgataaa tatctaagtt tttttatggg attatctggt ggaataatgt tggctgtagt
    49501 ggtgtttgat ttaatgaaag aatccatgga caaaatgggg ataatcaata cagttatatt
    49561 tacgtttgtt ggagctctca taactatgta cataaaaaca aaattagatg tgtctggaaa
    49621 tatggcatct ggatatctta tattcataag tatattacta cataatttac cagaaggact
    49681 agccattggt tcttctttta tgtcaactga aagtttaggt attacacttg ctatagttat
    49741 agctctacat aatataccag aagggttagc tatggcatta ggcttagttt gcaataaaat
    49801 gaaactaagt aaagttattt tgtttactgt aatagctgga ttacctatgg gtctaggaag
    49861 ttttttaggt gtttattttg gaggagtatt tacttctctt ataggagtat ttcttgctac
    49921 agcaggaggt actatgatgt atgttgtatt ggaagaaatt tttccacatt caaaaagtgt
    49981 gtattgtata attggtttct tgttaggtac aatgattgta aattatatat aaaattaaaa
    50041 tgaaagcagg catacaaaag atgaaaacta ttataagtaa tattgatata aataatattg
    50101 attatgagga aataaaaata caagcaaaac ttcttagaga aggtaaaaca gttatttttc
    50161 caactgagac agtatatggg ttgggtgcaa atgcattaga tgaaaatgca gtaaagaaga
    50221 tttatgaagc taaaggaaga cctagtgaca atccattgat agtccatata tatgaaaaag
    50281 aagaagtata tgacttagcc aaagatataa gtgataaagc taaacttgtt atagaaaagc
    50341 tttggccagg acctataaca attatattaa ataaaaaaga tataattcca tacaaaacta
    50401 gtggagggct tgatacagtt gcaataagga tgccttctaa tgttattgcc agggcaataa
    50461 taaaagaagc tggtatacct attgcagctc cttctgcaaa tatctcaggt cgcccatctc
    50521 caacaaaagc aaaacatgta tatgaagaga tgaatggaag agtggatgga atagttttag
    50581 gaggagacag taattttggg ttggagtcaa ctgtattgga tttaacagaa gagactccta
    50641 tgatactgag accaggaagt ataactaaag aagttttaga ggaacttctt ggagaggtaa
    50701 agcttgaccc atcattaagt aaaaaagaag ataatcaaaa agctaaagct cctggaatga
    50761 aatataaaca ttattctcca aatgcagatg tatatataat atctggaaaa agagaaaatg
    50821 tagcaacaaa gattaatgat atgataaaat ctaatagaga caaaggtcta aagacaggtg
    50881 taatgtgtat tagtagaaac cgagagtttt atgatggaga agtaatcgat ttaggaaact
    50941 ctcttgaaga agttgcaagt aatctgtttg atgctcttat agaaatggac aaaaagggta
    51001 ttgatgtcat atattcagaa gagttcccta agactggagt tggacaagca attatgaata
    51061 gactactgaa gtcagcagga tacaaagtga taaaggctta agagggagtt gtaaaatatg
    51121 aatatactta ttgtgtgtac aggtaatact tgtagaagtc ctatggctga ggctatacta
    51181 aggaaagcaa ttaaagaatc tggaagaagt attgaagaat attctatatc atcagcaggt
    51241 atatctacag caaatggaat gggtgcttct gaaaattcta tagaagtact aaaagaaatc
    51301 ggtatagact tatcaaatca tagaagtaaa gtaattacta aaaaattaat tgatgaatca
    51361 gatataatac taacaatgac taaatctcat aaagaaattt tagtacaagc agttccaaaa
    51421 tgcaaagaaa aagtgtatac ttttaaaggg tttgcaaata aaaatgagga agatatatct
    51481 gacccatttg gtggaaattt ggatatttat agaagcacta tgagagaaat aatgtattct
    51541 gtcaacgaaa tagtaaaaaa aatatgaaac ggaggataaa caaatgaaga taggattagg
    51601 ctgtgaccat ggaggatata atttaaaaaa agaaataata agctatttag aaagtaaagg
    51661 tatagaatgt gtagattatg gaactaataa tgctacagat tctgttgatt atcctgttta
    51721 tggagaaata gttgcaaatt cagttataaa taaagaagta gattatggaa tattatgttg
    51781 tggtacaggg ataggaatat ctttagctgc taataaggtt cctgggataa gatgtgcagt
    51841 tgtatcagat gtattttctg caaaaatgtc aaaagcacat aatgatgcaa atatgttatc
    51901 attaggcgaa agagttttag gaaaaggtct agcacttgag atagttgaag catggattaa
    51961 tacggatttt gaaggtgata gacatgctag aagagtaaac atgattaaat caatagaaga
    52021 aaaacataat aaataataaa aattacagtt ttatcaggag gaattatcaa aatgagcaaa
    52081 gtggtagaga caaaccatcc attaatacaa cataaattaa ctttaatgag agataaaaat
    52141 actggttcta aagactttag agagctttta actgaaattg caatgttaat ggggtatgaa
    52201 ataacaaaag atataccatt aaaagatgta gaaatagaaa ctcctattca aaaaacatca
    52261 tctaaagtag ttgcaggtaa aaaattagca ataattccaa ttttaagagc aggtcttgga
    52321 atggtagatg gattagtgag cttaatgcca gcagcaaaag ttggacatgt aggactatat
    52381 agagacccag aaacattaaa accagttgaa tattattgca agcttcctca agacatagga
    52441 gaaagagata taatagtagt tgaccctatg cttgcaacag ggggttctgc tgtagcagct
    52501 atagatttac ttaagtctaa aggagctaaa agtataaaat tagctaattt agtagctgca
    52561 ccagaaggta tagcagaagt gcaaaaatat catgatgatg ttgatatata tgttgcatca
    52621 gttgacgaaa gattaaatga acatggatat ataattcctg gtcttggtga tgctggagat
    52681 agattgtttg gaactaaata aaaataaata actataaata tttattaggg actttcttat
    52741 atagtgtata taattttatg taagaaggtt cttttttata tattttttct caaaatagga
    52801 attattgaat tgataaattt ctcgaattga gaataaaaag tttttaccaa ttaaaaaaga
    52861 ttgcttattt tacaaggttt tatagaatag tagtctattt taatgtggca tgttagttgc
    52921 ttacgattaa gattataggt attaagtgta ttagttaaat tgagaattga atattaataa
    52981 tattattggg agtggtaata catgaagaat tgtatagtag taagaggggc tggagattta
    53041 gcaacagcag ttattcataa attacacaac agtggtttta aagtagttgc gttagaaata
    53101 gaagagccat tagctataag aaggcaaatt tctttttgtg aggctgttta tgaaaaaaaa
    53161 gtaactgttg aaggtgtaga atgtatattt tgcaatactg aaaaagaaat agaggaagtt
    53221 ttatctcaac ataaagtagc cttgattata gacccaaaag gagaaaaatt atctaaatta
    53281 aatccaatcg ttttggttga tggaatacta gctaagaaaa acttaggtac aactaaagat
    53341 atggcaccac ttacaatagc tttaggtcct ggattttgtg caggagaaga tgtagatgtt
    53401 gttatagaga caatgagagg tcataatcta ggaagaataa taactaatgg tagagcagaa
    53461 aaaaatacag gagtaccagg agcaataaaa ggtttttcta aagagagagt tatgcattca
    53521 cagtatgatg gcataatgga aaatgtatgt aagataggtg atacagttga aaagggagac
    53581 ctactttgct atattaataa ttatgaaaaa aaacatgaag ttagagcaac aatatctgga
    53641 gtccttagag gtttattaaa ggatggagca aaggtaaaca aaaatttaaa aatactagac
    53701 atagacccta gaaaagaaga agttaagaat gcttttacaa tatcagataa agctagatgt
    53761 atagctggag gggttttaga agccatacta aacaatggga tttatcccca aaattaattt
    53821 atattagata aagctattaa tattttatta agatgatata ataaatttaa tagattaaag
    53881 agagcatatg acgggtattt aaaatttaaa tggtaaaaat gctctttttt tattggacat
    53941 tcaattaaca tgtgtatata atataaaaat aagtatttat ttaggttgaa atctaataaa
    54001 tatataatac cagtacataa gcaaagagga gaaaagtaaa ttatgagacc atcatgggat
    54061 gaatacttca tggaaattgc agaagtagtg aaaaagcgtt caacttgtat tagaagacaa
    54121 gtaggagctg taattgtaag agacaaacaa atattaacaa ctggatataa tggttctccg
    54181 agaaatcttg aacactgtga aaatattgga tgtaagaggc aggaattaaa tattccctca
    54241 ggagaaaggc atgaattatg cagagcatta catgctgaac aaaatgcgat aatacaagct
    54301 gctcataatg gtattagtgt agatggggca actttgtatg ttactacaag accttgtgtt
    54361 ttgtgtgcaa aaatgtgcat aaatgcaggt atattgaaaa ttgtttatga aggtgattat
    54421 ccagatgata tgtctacaga attattaaaa gaagcaggaa tagaactcat aaaattttag
    54481 tggataaaat ttatatgaca ataaatgtca aattatgaca ctgaaataca atggtatcaa
    54541 atgattaaaa gaaagtattt gaaaaatcat cagattagta gtaagatata ttttataatt
    54601 aaataaattt atgagataga ttaattacat gttatttatt ttataataat gagggatact
    54661 atttatgagt aaaagaaata cacatacaga aattgcaaag ttgtttagtt taataagtca
    54721 aataggattg atgattgtaa tatcaatatt aggatgtact ttcttaggaa aatttttaga
    54781 tagtaaattg aatactactc cagttctgac aataatattt ttattgttgg gtgttggagg
    54841 tgcttttagt ggtgtttata aaactctaat agtatataca cgaaggaagt gatatattgg
    54901 atataaaatt acttaaccag gtaaggtcag taacaaaagg tatagtaata tttgatgtag
    54961 ttttaattgt gctaatgttg ataacatcaa cattaagtaa accagtatta ttaggactta
    55021 tatttggctc tataatagct atgttaaatt ttagattatt ggcgatatca ctggaaaaat
    55081 cagtgacatt tcctgctggg aaggcacaag cttatgcatc agcacaatat gctgttagat
    55141 tatttataat ggcagttgtt ctaattgcat cagctacagt accacattta aatataatcg
    55201 gaacagcatt gggattattg agcacaaagt ttgtcatatt atcaaaaaac tttataaata
    55261 aattaaagag gaaggaggca taagtatgaa tcaagcgcat tattatctca taggaaactt
    55321 taagattagt gaaacaatac tagtaagttg gggaataatg gcctttttag cgatagcatc
    55381 ttattttttg actagaaact taaaaaaagt tccaactagt aaagttcaaa tattcttaga
    55441 atttgcagta ggtggtcttg ctaaaatggt tacagatgtt atgggtaaaa atacagtaaa
    55501 aagaatgcca tatatgatac catacatagg aagcttgttt ttatttttcg catgttcaaa
    55561 tttaagccca ttacttggat taaggtcacc aacaaccgac ttagacacaa ctgctgcatg
    55621 ggcaatgatt acatttttta tgatttattt tgcaggagtt aaatttaagg ggttatcata
    55681 ctttaaagaa ttggctcaac cacttgccat aatgttacca atcaatatta taggtgagtt
    55741 agctagacca atatcattaa gtttccgtcc atttgggaat attttaggtg gaacaataat
    55801 aatgggtctg ttttatcaac ttttaggttt tatatctagt ttaataccag gattatcaat
    55861 accaattgga gaaatattaa taccagtccc attacacttg tactttgact tatttgcagg
    55921 attgttacaa gcatatatat ttataatgtt aacaatggta tttatatcaa gtgcaggaga
    55981 gttagattaa gaaatcaact tatattaaga taaaaataaa ataatttaaa aaattaaagt
    56041 tttaaggagg aaataattat ggaaacagca atagtagcag cagcatcagc aataggagca
    56101 gggatagcag ttgcaacagg tataggtgca ggtataggtc aaggtatagc agcagctaaa
    56161 gctgcagaag cagtaggaaa ccaaccagaa gctaaaggtg atataacatc aactttatta
    56221 ctaggagttg ctatagcaga gtcttcagca atatatggtt tggttatatc aataatactt
    56281 ctattcgtaa atccattctt taaatactta ggaatgtaga tttagtcctt aaatattttg
    56341 agataggttt ataggtaaat catctcaaac ttataatcat gagatgaact ttatcatctc
    56401 gtgattataa gtagttatga tttatggaaa ggaggataat tatggaaaaa gcactagtag
    56461 gtataacgtg ggaatttgtg ttccaaattg ttaatacttt tataatattt ttacttctga
    56521 gaaagctttt attcaagcca gtattaaata taattgaatc aagagaaaat gatattaaaa
    56581 gtgatttggc agaaggcgaa aaagcaaaaa atgaaggttt agctctgaaa aaagaatatg
    56641 agtcaaaaat caattttgcc aaagatgaag gtcaagaaat cataaaacaa gcaactataa
    56701 gagcagagca gaaatcagat gatatagtaa atactgcaaa gaaagatgct cttgatataa
    56761 aagaaaaagc aaacaaagat atagaacaag aaagacaaaa ggttataaat gaaatcaaaa
    56821 atgatatatc taacatagca ctacttgcag catctaaagt tattgaaaaa gatttagata
    56881 aatctaaaca tgaagaattg atagaaaact ttataaaaga ggtaggggaa gctaaatgat
    56941 aaatgtaata gcaaatagat atgccgaagc cctatttcaa ttaggagaag aagaaaattc
    57001 aactgatgtc ttattcaaag aactagaaaa agtagtagat atgatgacta aagttagtaa
    57061 agatttctac aaagttttaa aatcaccatt agtttcaaaa tcagaaaaga aaaacttggt
    57121 agaaattatt tttagtaagg aagtaagttc taacataaaa aactttttaa aagttttagt
    57181 agataaagat agaatatcat atttagaaga tatcgaatta gcttataaag aattattaaa
    57241 taagaaaaac aatgtaattg atggagtagc aataagtgct attccaatga gtgaaacaga
    57301 tattaaagaa cttgaagtca aactttcaaa taaatacaac aaaaatgtta ctatagaaaa
    57361 tgttgttgac aagactatac tagggggagt tctagttaga attggaaatg aacaaataga
    57421 tggcactgtg aaaactcgtc ttgataagat gaaagaaaag ctatctgaag taatatctta
    57481 agaatggcgg tgaacccatg aacttaaaac ctgaagaaat aagttctata attaaacagc
    57541 aaataaaaaa ttatgagaat aaagttgagt tgacagatac aggtagtgtt ttaacagttg
    57601 gggatggtat agcgagtgta tatggattag aaaaagctat gtctggtgag ttgctagagt
    57661 tcccaggtga aatatatggt atggcactta acttggaaga agaagtagtt ggagctgtta
    57721 tccttggaga tgacagtgaa ataaaagaag gcgatatagt taagagaact ggaagaatag
    57781 ttgaagttcc agttggagaa gctttaatag gtagagttgt aaactcacta ggtcagccaa
    57841 tagatggaaa aggacctata gcgtacacaa aaactagacc agttgaatct gaggcacctg
    57901 gtataataga tagaaggtct gtttatgaac cattacaaac aggaatcaaa tcaatagatt
    57961 caatgatacc aattggtaga ggtcaaagag agttaataat aggtgacaga caaactggta
    58021 aaacatctat agttattgac actatactaa atcaaaaagg aaaagatgtt atctgtatat
    58081 atgtagcaat tggacaaaaa cgttctacta tagctcaatt agttagctct ttagaaaaag
    58141 gtggagcttt ggattataca atagtagttt cagcaacagc atctgaatca gcaccacttc
    58201 aatatatagc accatatgct ggagcagcta tgggtgaaga atttatgtac aatgggaaac
    58261 atgtacttat agtgtatgat gatttaagta aacaagctgt tgcatataga gaaatgtcat
    58321 tgttacttag aagaccacca ggacgtgagg catatcctgg agatgtattc tatttacatt
    58381 caagattact tgaaagagca gctaagttat ctgatgaatt gggtggaggt tcaatgactg
    58441 ccttgcctat aatagaaact caagctggtg acgtttctgc atatatacca acaaatgtta
    58501 tatctataac agatggtcaa atatacttac aaccagagtt attctattca ggtgtaagac
    58561 cagcagttga ccctggtata tcagtatcaa gggttggtgg ttctgcgcaa attaaagcaa
    58621 tgaaaaaagt tgcaggaaca ttaaaacttg catattcaca atatagagaa cttgcagcat
    58681 tctcacagtt tggttctgac ttagatgaag atactaaaaa gagacttgct caaggtgaaa
    58741 gaatcgttga gatattaaaa caaggtgagc atcaaccaat aaaagttgaa aatcaagtta
    58801 tgataatata tgctgttata aataatcatt tagaggatat tccgatagat aatatagcta
    58861 gatttgaatc agaattgtat gcatttgtag ataataatta tccggaaata tcaagaaaaa
    58921 tattaggtgg agaagacttc actcatgatt taacagatgc aataaatgaa tttaaagaaa
    58981 agtttgttgt tgaagtataa tcctttttaa aaaaggaggt aaattaattg gcaggagctg
    59041 gaatcaaagc aatcaaaaca cgtatgggaa ctgttgaaag tacaaagcaa ataactaaag
    59101 caatggaatt agttgcatct tctaagctta gaaaagcaaa agaaaaggct gaagattcaa
    59161 gagaatattt taatacttta tacaatacag taaaagatat tgcccaaaca acacgtggaa
    59221 ttagaaatga atttttaaaa gaaagagaag taaaaaataa atgctatgta gtagtagctg
    59281 gagacagagg acttgcaggt ggatacaatt ctaatgtatt aaaggaatct gtctctcata
    59341 tgaaaggtaa aaaggaaaca gtgattactg ttggaaagaa agcacatgaa tttttttcta
    59401 aaagaaacta caatatagca aaagatataa atagtgttga agcttgtgga tatgaagatg
    59461 cgacagaaat ttcacaaact attattgacc tgtataaaaa aggtgaagta gatgaagttt
    59521 atattgctta tacaaaattt aaatctgctt tatcacaaga agttgaaatt ttgaaattgc
    59581 ttccattagt ctttgaaaaa gatacagacg aacaaggaat ggcagtaaaa gaagaaaaac
    59641 aaaatagatc aaaagtacaa tatataccat cagcagaagc agttttaagt tatattgtac
    59701 ctcagtttat atcaggtaca gtatatggtg gaattttgga atcttttgca tcagagcaag
    59761 gtgctagaag aactgcaatg gaatcagcca cagacaatgc gaatgaaatg ctatctaatt
    59821 tagagttaag ttataacaga gcaagacagt cagctgtaac tcaagaaata acagagatag
    59881 ttggtggagt tgaagctcta aaatagggag gttaggaaat ggcaaatgta ggtaaagtag
    59941 tacagattgt aggagctgta ctagatgtta agtttgatag tgaacaaagc ctacctaact
    60001 tattaaatgc gttagtaata aagttaggag ataaagaaat agttgcagaa gttgctcaac
    60061 atataggtga tgatactgta agatgtatag ctatgagtgc aacagacgga cttgtaagag
    60121 gtatggaagt tgtagataca ggagggccaa taagtgttcc tgttggagat gaaactttag
    60181 gtagaatatt caatgttctt ggaaaaccag ttgatgggaa accagctcca aaatctgcac
    60241 ctaaattacc tatacataga ccagcaccgg cgtatgatga actagaaact acagcagaga
    60301 tactagaaac tggtattaag gtagttgact tactagctcc atatctaaaa ggtggaaaaa
    60361 taggtctatt tggaggagca ggagtaggaa agacagttct aatacaagag cttataaaca
    60421 atattgctaa gcaacatggt ggtatttctg tattttcagg agtaggagaa agaacaagag
    60481 aaggtaacga cctttatggc gaaatgagtg agtctggagt tataaataaa acagctctag
    60541 tatttggtca aatgaatgaa ccacctggag cgagaatgag agttgcttta actggactta
    60601 caatggcaga acattttaga gatgagcaag gacaagacgt tttacttttc gttgataata
    60661 tattccgttt cacacaagct ggttcagaag tttcagcact tctaggacgt atgccatcag
    60721 ctgttggtta tcagccaaca ttagctactg aaatgggtgc acttcaagag agaataacat
    60781 caactaagaa aggttcaata acatctgttc aagcagtata tgtaccagca gatgacttaa
    60841 ctgacccagc accagctaca acattctctc acttagatgc aaaaacagtt ttatcaagac
    60901 aaatatcatc actgggtata tatccagcag ttgaccctct tgaatctaca tcaaggattc
    60961 ttgaccctag tatagtagga aaagaacatt atgaagtagc tagaggtgta caatcaatac
    61021 ttcaaagata taaagaactt caagatataa ttgctatact tggtatggat gaattatctg
    61081 atgaagataa gttaatagtt gcacgtgcta gaaagataca aagattctta tctcaatcat
    61141 tcacagttgc tgagcaattt acaggaaatc caggtcaata tgttcctgtt aaagagactg
    61201 taagaggatt taaagaaatt cttgaaggga aacatgatga cttaccagag tcagcattct
    61261 tatttgtagg aacaatagaa gacgctgtta gaaaagcgaa gggaagtatg tagtcatggc
    61321 cagtgaattt tcattgaaag ttgtaactcc aagtaatact ttttatgatg gagatgttga
    61381 aatgatagta gttagaacta caaaaggaga caaaggggtg ttgaaaggtc atataccatt
    61441 tgtttcaggt atacctgtag gaactttaaa gataaaaaaa gagggaagtt ttaaagaggc
    61501 gaaaatagca gaaggattca ttaatgtaac tcaagataaa actgtcatat tgacagaatc
    61561 tgctgagtgg atttaataaa ttaatttaga ttataaaaag tcattttgac caaaaaaact
    61621 tttgggtaaa atggcttttt tgcgttttgg tgttaataaa ataacgataa aattgtaagt
    61681 ttttagtgat aataaattca caaaatgttt aaatttactg caaaattatg ttgtaattaa
    61741 taagataaag aagatttaga tagcttttat gtaagtgaaa aagtcttcat ataagaaata
    61801 catataaaat ttttataaaa tttaaaaaat ttgcttagtt gtgtagtata ataaataata
    61861 taatagattt gtatataata ttcattacaa ataattttaa aagttacagt tttattataa
    61921 tgattattaa attaagataa gtaacataaa ctaaataata atgtgtatta tcgatagtaa
    61981 atttataaat tcattattaa ttattgaaag aagtattata aattttctgg aggaacaatg
    62041 aatatatttg atattggcgt agatataatt gaaattgata gaataagaaa ggctgtagac
    62101 aaaaataata ggtttttgga gaagatattt acagatagag aaatagagta ttttaattct
    62161 aagaatttta aagcagaaag tatagcaggt aatttcgcag ccaaggaagc tataagtaaa
    62221 tctataggta caggaattag attgtttaat tttaaagata tagaagttct cagaaatgaa
    62281 atgggaaaac caatagtaaa aacttataat aatctagcaa aaatgtgcat agattataat
    62341 gttttagaaa taaaagtttc aatatcacat tcaaaagatt atgctatagc aaatgcgata
    62401 accataatta aggactaagg agtgattaca ttatgatgga taaaacagca aaagaaataa
    62461 tgacaacaga tgtaatagta gcaaaacaag atgatagtat agcagatgta gctaatatgc
    62521 taattgcaga aaaaatagga ggtctgccag ttgtagattc agagaataga gttgttggaa
    62581 taatttctga aacagatatt cttaaaaaag aaaaatatat agaagcacct ctctatataa
    62641 atctattaca aggattgatt ttcttagatg acttaaaaaa agttgaaaaa gatataaaac
    62701 aagtagctgc ttataaggtt ggagaactta tgtctaaaga tataataaag gttcatgaag
    62761 atgataagtt tgatgatgta gctaatgtaa tgattaaaaa atcaataaac agagttcctg
    62821 tagtagatga tgacaacaaa cttaaaggta taatttgtag atatgatata ataaaagctt
    62881 tatacaatga ataaactgaa gtaggaggtg tgatgtgaga aaaaagtgga ccatagtatg
    62941 tattatgttc ttggcactgg ttataattgt aataggatgc caaaaacgac agtccacaaa
    63001 agaagaagta tacaaagatt ttcaaaagca gatttctgat atgaattatt acagttgtaa
    63061 agctgaagta gaagtagttg gaaataaaag cccacacaat tatgttttaa ttcatactta
    63121 taaaaaaacc gataactata aattagaagt aatttcccca aaacatttaa aagggaaaag
    63181 tatagaatat caaggtgata aaatattagt taaaaatcca aagattagtg atgtagtgga
    63241 gttacctaat acaggaaaaa ataatcaata tctttttgta ggagacttta taaaaaatta
    63301 tcttcaaaat gaggagatga aagtaaagtt atccaaagga catttggttt tagagacttt
    63361 tattcctggg gataataaat attttaacaa gcaagtatta tatgtaaatg ctgacacaaa
    63421 aaatcctgaa aaaatggaag tgttagataa agagggagtg ccaagattta cagtaaaata
    63481 caaagatttt gaatacagaa actaaggggg actaaagaca tgcaaaaaat aacagtgcct
    63541 acatgggcag agataaatct agataactta agatttaact taaataatat taaaaattta
    63601 ttagaagaag atattaagat ttgtggagta ataaaagctg atgcatatgg acatggtgca
    63661 gtagaagttg caaaattgct agaaaaagaa aaagtagatt acttagcagt agcaagaact
    63721 gctgaaggaa ttgaacttag acaaaatggc ataacacttc ctattttgaa cttgggatat
    63781 actccagatg aagcttttga agattctata aaaaataaaa taactatgac agtttattct
    63841 ttagaaacag cacaaaagat aaatgaaatt gcaaaatctt taggagaaaa agcctgtgtt
    63901 catgttaaaa tagactcagg gatgactaga ataggtttcc aacctaatga gaagtcagta
    63961 caggaaataa tagaattaaa taaattagaa tatatagatt tagaaggtat gtttactcat
    64021 tttgctacag ctgatgaagt aagtaaagag tacacttata aacaagctaa taattataaa
    64081 tttatgtctg ataaattaga tgaggctggt gtaaaaatag ctataaaaca tgtatcaaac
    64141 agtgcagcta ttatggattg ccctgattta agattaaata tggtaagagc aggaataata
    64201 ttatatggtc attatccatc tgatgatgta tttaaagata gattagaatt aagaccagcc
    64261 atgaaattaa aatcaaaaat cggacatata aaacaagttg aaccaggtgt aggaataagt
    64321 tatggactaa aatacacaac tacaggtaaa gaaacaatag ctacagttcc aataggatac
    64381 gcagatggat ttactagaat ccaaaaaaat ccaaaggttc ttattaaggg agaagtgttt
    64441 gatgtagttg gtagaatatg tatggatcaa ataatggtta gaattgacaa agatatagac
    64501 ataaaagttg gagatgaggt tatactattt ggagaaggcg aagttacagc tgagcgtata
    64561 gctaaagact taggaactat aaactatgaa gtgttatgta tgatatcaag aagagttgac
    64621 cgtgtttata tggaaaataa tgagcttgta caaataaaca gttatttgct aaaataaaac
    64681 catgatatta taatctggga ggcgattttg tgtacgataa gagtaaagaa aaaatagaag
    64741 ttactttacc tgactctctg atttctgaag ttgatagtat agttcagatg gagaacagta
    64801 acagagaaga ttttgcaaaa gctgcttttc agttctatat aactcagaaa aagaaaattc
    64861 atattaaaga atctatgaaa acgggttata gagaaatggg tcaaattaat ctgtcactag
    64921 ctgaattagg tatgacagtt gaagaagtat cttctgatga taaaaatgaa gggaagattg
    64981 cccaaggtga gtactaattg tgaaataaag cgtggtgatt tatattacgc tgatttaagt
    65041 ccagttgttg gttcagagca gggaggcgtt agacctgttc tgataataca aaatgatgta
    65101 ggtaataaat atagtcctac agttatagta tcagctataa catctcagat taataaagcc
    65161 aaattaccta ctcatgtaga gataagttcc aatgaatatg ggcttaataa agactcagta
    65221 attcttttag agcaaattag aactatcgat aaaaagagac tgagggaaaa aattggttgt
    65281 ctagatgaaa atatgatgat aaaagtagat gatggacttc aaataagttt aggattgttt
    65341 actttttaaa gagggatttg tcttttatta gacaatccct tttttctttt aaatatctct
    65401 taaggtttaa ttttaatgta ctatgttaat aaaattaaaa ataacgcaaa aaaatagcat
    65461 aaaagtgata taataatatg gaattgatat aaaattacga actcaaggga ggtaattgca
    65521 tgagagacca taaaggatta aatgagattg cgcgtatcat aagaagagat atagtttcaa
    65581 tgatacatag agccaaatct ggacatccag gagggtcatt atcagtagtt gaaatactta
    65641 ctgcgttata ctttgatgaa atgaatgtgg attcttcaaa tcctaaaatg gaggatagag
    65701 atagatttgt attatcaaaa ggacatgctg caccagcatt atatgctaca ttggctgaaa
    65761 aaggctattt tgataaggaa gaactgaatg gattaaggaa gataggaagg atgttacaag
    65821 gtcatccaga catgaaaggc acgccaggtg tggaaatatc tactggttct ttaggtcaag
    65881 gtttttcagt agcatgtggt atggctatgg catcaaagtt ggataatgct ccgtggaatg
    65941 tgtatacttt gcttggtgat ggtgaggttc aagaaggaat tgtttgggaa gctgctatga
    66001 gtgctgcaca ttataaactt gataatttaa ttgctttttt agataataat ggacttcaaa
    66061 tagatggaga tatagaaagc gtaatgagtt taggttcaat agttgataaa tttaaagctt
    66121 ttggttggaa tgtaattgag atagatggac atgattttga ccaaatattt gcggctcttg
    66181 atatagctaa atcaacagtt aaaaaaccta caatgatagt tgcaaaaact ataaaaggca
    66241 aaggaatatc ttttatggaa aatcaagcag gatggcatgg gacagctcca agtgatgagg
    66301 agctagaaaa agccttgctt gaattaggag gtgctgacaa tgagtaaaat ggcgacgaga
    66361 gaagcatatg gtaaagcatt agtaaaatta ggtcaaataa atgacaatgt tgtagtatta
    66421 gatgcagatt tatcaaagtc tacaaaaaca catgattttt acaagtcatt tccagataga
    66481 ttttttaata tgggtatagc tgaacaaaat ttaataggcg ctgcttgtgg attatcaact
    66541 gctggtaaaa taccttttgc aagtactttt gctatgtttg ctacaggaag ggcttttgag
    66601 attataagaa attcagtttg ttatccaaag ctaaatgtaa aaatatgtgc tactcatgca
    66661 ggtcttactg ttggagagga tggagcatct catgaaagtg tggaagatat tgctataatg
    66721 agagctatac caaatatgac agttcttgtt ccagctgatg gagttgaaac agaaaaaatt
    66781 atttttgaaa tagctaagta taatggacct gtttatgtta gattagggag aagttcagta
    66841 ccagttttat ttgatgaaga ttataaattt gaaataggaa aaggtacagt cttaagagaa
    66901 ggaaaggatg tatcaattat agcttgtgga attatggtaa atgaagctct attagcacaa
    66961 gaaaagttgc aagaagaagg tataagtgct agagttataa acatgtcctc gataaaacct
    67021 atagacaaag atttaatatt agaatcagca aaagaaacga atgctattgt aactgtagaa
    67081 gaacatagca taattggggg attaggttct gctgtaagtg aggtagtagg agagtcttgt
    67141 ccaaccattg taaagaaagt tggaattaaa gatacatttg gagaatctgg tactccaaac
    67201 gaattgttaa aaaaatatga attaacttgt gatgacataa taaagactgt taaagaagct
    67261 attattgcaa aaagaatgta agagatataa attattcatg tttgttaata atataatata
    67321 tttaaaagag aggtataaag tgttatatta atttatatct ctcttttttt tatatgatat
    67381 caatatatca aaaatgtaat aaaatattca aatttttaca aaaatagaga aaatattcaa
    67441 atatatattg actattcaga aaaatatgac taatatataa tttatagaga aattaatttt
    67501 atatataatg actacttaga taaaagaatc taaaaaaatt atgagaggag gagtagggta
    67561 taaaatcaga ttataagttt taagttatta tactaaaaag ctataaaaca gttatcatgt
    67621 attttatgtt aaaggaaatt gtaggtagtt tatcgaattg tttaatcaga agaaaaaatt
    67681 tcacatgggg aggtaactga gatatgtcag aaaaagtaaa tgttaaaaca gtcatcagtt
    67741 tcgcaggtgc gtatgtagca acagtaatcg gttctggatt tgcaacagga caggaaataa
    67801 tgcaattctt ctctttttat ggttttgcag gtattattgg tgggataatt tcaatggtat
    67861 tattctcatg gatgggtgct tcagttatgt caaaaggtaa agagcttcaa cttaaagaac
    67921 ctatcaaaat ttatcgtgtt tattgtggta agtatttagg aatattcttt gaatggtttg
    67981 gacctttatt cttatttggt gttttcgtag taatgatttc aggagcagga gcaactttaa
    68041 ctgaatacta tggattaaat ccatttgtag gtagagtagg tatggcagta gtagcattat
    68101 taactgtttc actaggtctt gataaattat caaagatact aggtggaata gggcctataa
    68161 taataatctt tacactttta gttggtggta taagtttagc taaaaacata ggtaatatag
    68221 gagaagctgc acaagttctt agcactgtaa agatagctaa accagttcca aatgcctatc
    68281 tatctggtgt aatatatact acttataaca caattgttgt tatggcattc ttaactggat
    68341 taggagcaag tgctgctaac aaaaaagaag ctatttgtgg tggtatatta ggtggagtag
    68401 cacttatggc tgcagctata atgatgcact tagctattct ttctgatata ggaaacttat
    68461 attcaaaagc aataccatca ttattcttag cagataagat ttcaccagta attggagttt
    68521 tattctcaat aattcttata ttaggtatat atacaacagc tgtaccttta ttatggtcag
    68581 taactaatag atttgtagat gataaacatc ctaagtttaa attaataact ttaatagcgg
    68641 ctatattagg tcttataggt ggcttcctac catttgataa gctggttggt attttatatc
    68701 catatactgg atatatgggt gtcataatac tggtttgtgt tctttataga cagattacaa
    68761 aaacatctgg atatcaagaa ggaatcagtg acaaataagt attttttaat attgtaaact
    68821 caagagctat atgaaaacaa tgaaaatgtt ttcatatagc tctttttatt ttttagctcg
    68881 tttattatga aatagaaaaa acatgttttt tagttacatt acatatattt ataattatgt
    68941 ataaatatat actaatcaat aatttagagt ctaagataag tttataaatc atatatttag
    69001 aatatatggg aggagtgata agattgaatg taaaatttaa tattaaaggt ataatttatg
    69061 gagttatagc tcttgtattc gttatagggg gatttatatt cataccaagt atgtttgtag
    69121 agaaatctaa acccatagat tatacagtat tacaaagaaa ttcaatacca gaaaagatat
    69181 tagatgtgat ggataagtat acaaatgaag aaagagcatt agcggctaaa atcgataaca
    69241 aaatatacat tatagtgact agaggaaata ataaatatgg tatagaaatg gacaaaatag
    69301 aaagtgtggt tgaggaagga aaggatgttt tgagagtcaa gataaagtat aaagataagg
    69361 aagattcttt tccatacata gttgttgaaa caaatatgag tgaacttcca gatagaatag
    69421 aattaaatgc aacgaaataa gaaggtattt tataattaaa taactgcata ttgtacaata
    69481 aagtcatggt ttttattaat gtaagtaaac tgtatatggt tcttattgtt gtaaaagcca
    69541 tgacttaaaa tgcttataaa gtaagatatt aacagtagta tttattacta cattaaatgg
    69601 ggtctggaaa tacttaatat tctaactatt tggagtgata attctagttt cagtaactat
    69661 gtagtctaat tgtgcatcat gagtttcttt tggaatagaa tcgaatatct ggaagtcaaa
    69721 tgctatgccg atagttatag catcttttct taagttttct aaaaatctat cataaaatcc
    69781 tccaccatat cctaatctat agcaatgtat atcatatgct acagctggta caattacaac
    69841 atctaaggcc ttaatatcaa ttgtaggtga tttttcgtta ggttctctta ttccatatgc
    69901 tccaattctc aatccctctt ttaaatctgt tatttgagta gggattaatg tatgattttc
    69961 ttttattgtg atgggacttg atactatttt ctttagagac aaaagttttt tgattaaatt
    70021 atctgtttga acttcattgt taaaatttag ataaagcatt atattagttg catttcttat
    70081 atcttccatt tgaagtaatt tttcagttat taaatttgaa ttactaagta caaagtttgc
    70141 actcttattt tttcttgatt caataacttt ttttctaaat tcttttttca taaaataatt
    70201 cctcccttaa tatgttataa tgtgtacagc aattgtattt aatataaatt ttagtataat
    70261 ttattgtaat aaagcaatat atttgggtaa atgtaataaa aataacagct agtcatataa
    70321 taataatagt ttatgtaaaa ggagatgtat cttgtgattt caaagaagaa agctattttt
    70381 ttaggggtga ttttagtaat tataacagct atggttacat cagcatttca gttgacattg
    70441 gggaataaag ttgtaatatc gaaagaactc tatgaagact ataaaaaata tgataagttg
    70501 ttaggactag aatctattat aaaacaagat ttttataaaa aagtatcaga tactgatttg
    70561 gtaaatggag cagcaaaagg tctatttcta ggaacaaatg ataagtattc tggttattat
    70621 actaaagatg aaatggagaa tctaattaat gatagtgaag gttcttatgt tggtgtaggt
    70681 atgtatatag gggcatcaaa agatggtggc ttagtagtag ttcccatgaa agattctcca
    70741 gcagagaaag ccggtgtaaa atcaggggat aaattagtaa aagtcaatgg aaaatctgtc
    70801 tcatataaaa attcagatga agctgttcgt atgatgaagg gtaaaaaagg gaaaatagtt
    70861 gaactgacta tattaagaga agataaacaa ttgaacttta aagtaaaaac agaccagata
    70921 attgagaaga gtatagaaag taaagtaatt gataatgatt taggatatat agaaattacc
    70981 caatttatat caagtacata tactgacttt gatgaagctt taaaagaatt aaaagcaaaa
    71041 aatatcaagg gattagtaat agaccttaga aataatcctg gtggaatgct agatatatgt
    71101 aaagaagttg ctgatgagtt aattggtgaa ggaactatag tatatacaaa agataataag
    71161 ggaaatactg agtacttgaa atctgataaa gaaaaattgg gacttccaat agtagtgtta
    71221 actaatggag aaagtgcttc tgctgctgaa atattaacag ctgcaatcgt tgataataaa
    71281 gaaggtattt ctgtagggac tacaactttt ggtaaagggt tggtacaatc agttgtaaga
    71341 ttgaaggatg gaacaggata caagttaact actgctcaat attttacacc taatggagat
    71401 tatatcaatg aaaaaggtat aaagcctact attgaagaga aagatgaaaa taaacagtta
    71461 gatgtagcaa ctaagtggct tagagaacag attgataaat aaaatttaat ttttataaat
    71521 ttatattgta aaataaagaa ccttaataaa aggagtgtct caaaattaac tttttagggt
    71581 ctttaaaata aagtgtgtat tcttctaaaa agtagtgata attgaaatat taaatatcac
    71641 tatataaagg aaggtgcaca ctttttatgc ttaataaaaa caaaatatta aaaaacttat
    71701 tgaagaatat gatgttaaaa caactacaga tattcaagat atgcgaaaag atttatttgc
    71761 aagtacaatt catcaaatgt tagaagtata gcttgatgac catttaggtt atgatagata
    71821 tgacaataag aataaaaata ctaaaaactc tagaaaggga tatagaaata aaaatattaa
    71881 atcagatttt ggagaaataa ctttaaatat tccaagagac cgaaatggag attttgaatc
    71941 aaaggtaatt agaaattatg aaaatgatat atctcattct ctaatagata aaattactga
    72001 tagagttata cctttagctc atttaagtat ttattttgaa gaaaaaattt aaaatctaag
    72061 ttaataaaga aatatttcaa aaaaattaag aaattttctt aaaggagtaa taatttttgc
    72121 aaaaataaaa aaacatcaaa gtaaggctat gatttttaaa ggcatagcct tactttgatg
    72181 tttaattatt acttaaagaa taaattttta tttgtagtga aaactccgta gattctatta
    72241 acatgtatac agcaggtttt tgctttaatt tatttagagt cacgcaatat ctatatcatg
    72301 ggtaccacca tagttgtata ggaagttatt tcaccgaatc cttttcttac tttatcgtat
    72361 attatattgt tgtattattc ttaacattag tctaaagtac tttctataat ttactaaatt
    72421 cagtttgcaa gttattggct tgttctttaa ggactttaat taaatattct tctcctttgt
    72481 gcattaatcg attgctagga ccagtaatac taatagcaca tattaaatca ttattgcaat
    72541 caaaaatagg aactgcataa caagacaatc catattcata ctcttcattg tctattgata
    72601 aatttagttc cagtattctt tttttagcta acagaaactc gttatactct gtgattgtat
    72661 ttacagtacg cttttctaag ttattaaagt aatcttgaag aaattcttcg gattcttgac
    72721 ttaggaataa tttccccatt cctgaacaat acaaaggact aacaggtata agggttgttt
    72781 gtaattgata aaactctcct tctattgatt ttacaataat aacttcattt tgataacgga
    72841 tacctagatt tacggattct ccagtttctt tgctgatttt ttgcaaatag ggttctgcta
    72901 cagaaattaa tttattttct tggcttgttc ccttcgcata agataataaa cgataatcaa
    72961 gagtatagtc gctgttttct aattgcttta taacatgaat ctcttcaagt gttttaacta
    73021 tacgaaagac actagtctta ggaatagata atatttctga aattttagca atacctatac
    73081 ttcctttttc attaataaca tcaattattc taaaactatc aactatgttc ttgataatag
    73141 gactcttctt ctccataatt gcccaccacc tttcttttaa attctaagtc taattagtta
    73201 aaatggcaag acgtattttc aaacttcata tatgtaaagc tcactaatta ttagtatttt
    73261 ttcactaatt ttagttgttt ctttataaaa aagagataaa aacaaaaaaa ctttgttatt
    73321 tattattaaa ggtattgact atatgatttt ataatagtat tataattttg gaacgtgttc
    73381 cgaaattaaa aaagggggta ataaaatgaa agttagtatt attggtgcag gtgctgtagg
    73441 tgctacaact gcttttacac ttgctaaaac aagttttgta gatgaaattg caattgttga
    73501 tattgatcaa aaccgtgcaa aaggaaatgc attagatatt cttcatggat tatctttaat
    73561 gcatgaaaca agaattgttt caggtgatta tgattgtgca attaactctg atgttattgt
    73621 aattactgta ggagtacctg aaaaagttgg cgaatcacgt ttggttccat tacaaaaaaa
    73681 tgtaaagata cttcaggata ttataccaaa gatcacaagt acgagtccta acggattatt
    73741 attggttgta agtaacccag tcgacatcat aagttacttt tctcaaaaaa tttcagggtg
    73801 ggaagcaaaa cgtgttattg gtttaggtac aacccttgat tccgctcgtt taaattattt
    73861 aatcgctcgt gatttaaaaa tttcacaaac tgatattcaa ggtttagtaa ttggtgaaca
    73921 tggtgactct caagttgttg cttggagtca aacaagtgtt aaaggaacac ctttcttgga
    73981 ttatgttaaa tctaataaca tctcgttaca agaagattac tgtaataatt tggctcaaga
    74041 agttaaagat actgcgtttg atgtatggga tatgaaagga ccaaattgtt actgtgttgc
    74101 cttggcaatt gagcgtgtaa ttaaagcaat cgctcgtaat gagcatgcaa ttttaccagt
    74161 tagtcagcca gctgattcag aaatgtatat cagccagcct catataattg gacgtgatgg
    74221 tgtacaaaga agagttatct tatcttatga tactcaagag ttaaatgcat ttgatacgtc
    74281 ttatcaatca ttgcaagata ttgttaaaca aattgaaatt taattaaggg agaaggattt
    74341 catgaatatt agtcaaacaa agggtttctt taagttcctt atcttaactt tactaggtat
    74401 tgtattttta ttgattccat ttcggttcga gaatggcatg gatacaatat tatttcatta
    74461 tctaaaatta tttatttcag aaaaccatgc tgttattcaa acaattgtgg ttctgttggt
    74521 ttgtattagt gcaaccttat ctcttataga tcaattgtta ccaaatacga ttttacgtaa
    74581 acaaagatta cttaagaaac tgttctcaac gacacctttc tatgtattta atagaatcat
    74641 gggtgcaatt attgctatgc tttgttattt acaaataggt cctaaattca tcatttcaat
    74701 cgatactggt ggcgcaatgc ttgatttagg aacacaactt tctgtacttg taccattgat
    74761 gctactattt caaacactta ttttagagtt tggtgctatg gagtttttag gacaattgat
    74821 agggtttatt gcaaaaccat tatttaaact ttcagaaatt tgtgctgtga atataatcag
    74881 tgcctgggtt ggtcctggta atgctgcaat tattggtact aaagaacttt ttgaaaaggg
    74941 atactttaca gtaaaggaat ccgctgttat cggaagtcag ttctccatct caagtattgg
    75001 ttgggttgta ctggtttgtt cagttttaga cacaatggat cattttgctt taatattctt
    75061 aggaataact ctgataggta taatcttagc tttcataaat gtaagaatac cacctatttc
    75121 taattatcct gatacttatg ttgatggttc aacaacttct aaaattgtct ctagcacaca
    75181 agggacacga ctgcaacgtg ctattataca atcaagtatg cgtgcaaacc aagttacttt
    75241 aaaaaatttt acaagtaaga ttgataatat gagcttctat gttttatggc taacacctat
    75301 tattattttc tggggggcat tagcacttat tgtttcattg tatactcctc tattaacttg
    75361 ggtatcttat ccaatagaat tagtattgaa gttagcaaat atctctgaac cagcaattac
    75421 tgctagcgca attatgtcag gatttgcgga taactattta ccagttatct tgggcaaagg
    75481 attagaatcc attgaaagca aaacaatcat tactatgatg agcatcctac agcttatctt
    75541 tatgtcagaa atcgcaacat tacttcagtc atgtaaagtt gtaaaaagtt ttaaagatat
    75601 tattattata tttttacaaa gaactattat cgccctacca tttgtaatta tatttacaaa
    75661 gcttattcta taagatttaa aggttttaaa gtgcttgaat gattattctt taatagtctt
    75721 tcttttcata atttagattg atgaacattc cttgaaatat cttttgtata agggagtttg
    75781 ctaaaatata ttgttaattt tttaatattt atttaatttc ttatttaaag aaattttgaa
    75841 gtcatcactt caaatagtta tattgaatat tctatttatt tttgtgattt tcaaactatc
    75901 attatgtaaa gcattatata gccaacctgg atatctaatt gaatttgtta aaaattaaat
    75961 ttataaagat aaaatatgtg aattatatta aaaatataca taagtagaag atatagggtt
    76021 ggtaattcta atattacaag ccctatttta tattatttat ggagtcttta aaataaagtg
    76081 tgtattcttc taaaaagtag tgataattga aatattaaat atcactatat aaaggaaggt
    76141 tcctactttt agtttatgag gcactctttt tgtatgaaat caaatgtatt ttcatcattt
    76201 taacaatgaa aaagaggctt atctctattt ttaggaagcc tctataactt tatattgaat
    76261 ctatttatta actttgtaca tacatatacc acttatataa gtttcgtata tattaaagtc
    76321 cttatctgtt actataaaat ctgcctccat accttgatgt atggagccac aaacattatc
    76381 aatattacaa cttaaagcag ggatatatgt agccattttt attgcatctt ctaaagtggc
    76441 tatgttccaa tcaactatat ttctcacagc cttgtccata gttaatacac ttccagctaa
    76501 actcccacta tttaatcttg caatactatt ttttacattt acattaaact taccaagagt
    76561 atattttcca tcctccatag caccagctct catacaatct gtaattaaag ctatgttatt
    76621 actagactta gcatccatca ttattttaac agctattggg cttacatgat gaccatcaca
    76681 aattaattca gcataagtat cttttagtac catagcagcc ccaaccattc caggttctct
    76741 atgatttaaa ggactcatcc cattatatgt atgtacaaac actttagcac ctgaattaac
    76801 gacttgttta acttgctcaa atgtagctga actatgacca agagaaactg atatattatt
    76861 tttagttgca tatcttgtta attctattga acctttacgt tctggagcaa ttgctatttt
    76921 ccttattaaa tttttcgatt ttttttgcca taattttaat atattgatgt cagggtcttt
    76981 aaaatatttt tcattttgag cgcccttata tttttctgta aaaaatggac cttctaaata
    77041 aatcccttgt atttttgcac cctcaactcg attgaagcta ttgcttatat tttctacaga
    77101 atcacttagt gtatctacag aatcagttaa agttgtaggt aggaaagatg ttactccata
    77161 ttttaataag ccttttgaaa ttgtgtttat tgcttcaaat gtattgtcca tgacatctgc
    77221 acctaaaaga ccgtgaatgt gagtatcaac taagccagga gcaatatatt tacctgaaaa
    77281 atctataaca ttatcagtaa tattaggtct ttcttgttga aattcaccaa atttgccatt
    77341 aattatgcta aggtaacctt tttctttgat tccatgtttc ataaaaaatt tatctgcata
    77401 aataaaactt ttcaaaataa cctccttata attatactat cattgtggca ttgacgttta
    77461 taatatcatt ctattttctt gaaagctatt taacttacta tcttacatgt cttactctat
    77521 atacaaattt atcgcttcta gcaacactca aagtaaattc aataactata ttgtcatcat
    77581 tatatgtggt acgaagtaat ttcagacaag gtgaatctcc tggtacttcc aataacttag
    77641 cttccttatc agagattatt ccagctgaaa attcttcatc agcaacttta ataatctcgc
    77701 cataatcttc tctaaatatt tcatataaag gtttttgttc gattttttct tttgtcaatc
    77761 ctataaattc tttcatagga agatatgttc tttcaagcat cataggaagg tcatcagcaa
    77821 gtcttaaacg cattattttt atcatttttt caccaggagt tatacctaat ttttcagaga
    77881 aatactttgt actttctact acctcaaatg ataatacctt tgtacctggc ttttttcctt
    77941 gtgttctcat ataatctgta aagctataac tttccattaa gttttgagaa ttttgactta
    78001 gtgcagcaac aaaagttcct tttccatgtc ttttatatat atatcccata tgctctaact
    78061 cagccatagc tagtctaact gtggttctac ttactccata ttcatcacaa atttttcttt
    78121 cagaaagcat tctatcgttt ggttccatct cattttcaat cttagttctt aatatctcaa
    78181 caagctggtc atatattggt cttttatcat ttctttttat cataaaaata tagtcctttc
    78241 taagtggtta ttaccacaat ttgattatag aatatagaat tatttatgtc aatgaataaa
    78301 gtttaatcaa aattcaataa gtaaggctat taatttatta taaaattatg gtacattgac
    78361 aaaacaagta aaataattta tattcaaatt ggtaataacc actttgggta tattatagat
    78421 gaggtatttt ttattttaca gattaattta ttgtttagaa aagtaaaaat taataatgag
    78481 gagaatctag tatgattaca gtaataacat tcaacccatc tatagataga atgtatagag
    78541 tgaataatat aaacataggt gaggtgcaaa gggtagtaag taagaatgca actgctggag
    78601 gtaaaggatt aaacgtagct aaggtatgta aaattttaaa agaaaatcct ttagctatgg
    78661 gatttctagg tggatttaat ggagaattta taaaaaatga acttagaaaa ctagatatac
    78721 aaaataaatt tacaaaaata gagcaggaaa ctagaaattg cttaaacata attgaggaca
    78781 ataaagttag tacagaattt ttagaaaaag gaccaatagt agaaaaaagc gatttagaga
    78841 gatttgaaaa tgatatagag gaagtactaa aaaatactaa aatactggta gcttctggta
    78901 gttattgtga gaatatgccg atagattatt atgaaaagat aggaaatata tgtagagcaa
    78961 ataatataaa atttatatta gatacatcag gagaagcatt aaaaatagct ttaaaatcaa
    79021 aaccatattt aataaagcca aatatagatg aaataagaca tttattagga atgaatatag
    79081 aatcaagaga ggaaattatc ttgtcaggaa aaaaacttat tgaaatgggt gcagagaatg
    79141 tatgtatatc tttaggaaaa gatggtatgg tgtatttaaa cgaagatagt gtatatgatg
    79201 taaaagtacc agttgtaaag tgtataaata ctgtaggtag tggagatagc acagtggctg
    79261 gatttagtgt aggtatttta aggggttata aaatagaaaa tttacttaaa tttgcaaatg
    79321 cttgtggtat aagtaatgct ttaaatatgg aaactggatt tgtagatttg ggagaaattg
    79381 ataaatatca agatttagtt gaagtaaaaa agttaagtta aatacattta atgggaatat
    79441 aataaattta atgttgttgt aatagatttt aatataaaag atatagtctt atataaaaat
    79501 aggttagaaa aattcatttt taacctattt ttataataaa tatctatttt actgaattta
    79561 taattttctc tagtaatctt tgagccttga tacactcttc tccactaata gctggtttta
    79621 tattattttc tatacaatca ataaaatgat ttgatatatc ctcaaaaccc ttttgtttta
    79681 atatatttac ccatgcacca ctttgcttta aagttaggtt tccaccttct tctatttcca
    79741 gtacattaag attcttaact ctttgaatct taccctttga aagaatttca acttgttcta
    79801 actttgttcc agaatctcta tgcatagagg tgtttataga gaaattttta cctttaagtt
    79861 tatgacttac aaatataaga ttcttattgt ctgttaaaaa taaatcctct ccactaattt
    79921 caacatcttc atttgctaac cataaagcag tgtcaataac atgtatatag tcatctataa
    79981 gagtactgtc gaatctaaca tttcttaagg aatttaatcc atgtttacat atattgatag
    80041 atacaatttc tgtagcatta tttttaattt ctttgtacat aggacagaat ctacggttga
    80101 atccaaccat taaatttaag ttttttttcg tacttaactc gataagttct tctccttgac
    80161 ttactgttga agcaagaggt ttgtctacat atacatgaac acctaaattt aataatattt
    80221 ttataatttc gtagtgtgtt tctgtagagc tatgtagaaa aatacaatca cattttttag
    80281 ctagggattc aatagaatcg aatggcatga ttctataatc actacagact ttttcccttt
    80341 taactttatt tggagtaaaa gctcctacaa actcaaatct ctcagactta gttaatatag
    80401 gtaaatatgc cttttgagct atggagccaa gacctatcat tcccattttt atatttttca
    80461 taatactttc tcctaaggtt tttatattta cagaattgat tataattcag acacataaat
    80521 ttgtaaactt tgtatcaaaa aataaattta aagcttatat aagtaaatta gcgaaataag
    80581 aaatattgat aaagtaattt tgtaggatat ctataaaatt gattgatata aatattttat
    80641 gtattgacaa aaaattcaaa ttaatttata tttggattag tggtaattac cactttggtc
    80701 tgaacaagtt tttatcgtaa aataaaaata ctaaagtata tagagtatga ttttattaaa
    80761 tttttaaaga taaactataa aattaattaa aatctatagt gtatatttta tagtgagttt
    80821 aagtagtact aaaaaatcta agcaaaaaat tataaaagag tatatttttt tatagtttaa
    80881 agtggttata acctcattac caaatgtaaa cgttacaagt atgaaaggag aatgaaaatg
    80941 tttaaattag aagaacaaaa actaaaagat ttaggtgcaa taataacaac taatgaaata
    81001 aaacaacagc ctgaattatg gttagaaact tatgaaatat ataaatctaa caaagaaaaa
    81061 ttaagtagat tcatagatac aataagtaat aatcatgggc agtttagagt tatatttaca
    81121 ggtgctggaa cttcagctta cataggaaat tcaatacttc cttaccttaa aaataaaaat
    81181 gacataagaa aatacatatt tgaagcaata cctactacgg atatagtttc aaacccatat
    81241 gattacttaa aaaaagatat accaacatta ttaatttcat ttgcaagaag tggaaatagt
    81301 cctgaaagtt tggctgcttt aaatttaggg aataagattg tagataattt ttatcattta
    81361 gctataactt gtaatccaga aggagaactg gctaagatga ctaaaaacga cgaaaataat
    81421 tacttgttat taatgccatc aaaatcaaat gatgaaggct ttgccatgac aggaagtttt
    81481 tcgtgtatga tgttatctgc tatgttaata ttcgatagtt tagaagatga tgtagaaaag
    81541 tcatatataa atgcaataat tgaaatggga agaaatgtta tagatagaaa agatgaaata
    81601 catgagttaa taaataaaga ttttgataga gttgtatatt taggttcagg aggattaggt
    81661 ggtttgacac aagaagcaca actaaaactt ttagaactta cagcaggaaa aatatctaca
    81721 gtgtatgatt ctcctatggg gtttagacac ggaccaaaat catttattga tgaaaataca
    81781 cttgtatttg aatttgtatc taactgttta tatacaagaa aatatgattt agatgtttta
    81841 gaggagataa aaagggataa aattgctaaa ttcacttgtg cagtgtcagt agaaaatgaa
    81901 aataacttct caggaacaaa gtttgagttt aaagaaaagt ataataaatt accagatgtg
    81961 tatcttgcaa tgccatacat attgtttgca caaactatag cattgtttgt atcggtaaag
    82021 gttggaaata agccagatac tccatcagct acaggaacag taaatcgagt agtaaaaggt
    82081 gtaacaatat atgaatatta aaagataaga ttaaaatatt ataactaaat aatttgggag
    82141 ggtatcaatg tggcattagt aacaacaaca tcaatgctta aaaaggcaca agatgaaggg
    82201 tatgcagtag gagcatttaa tgtagaaaat atggaaatgg taattgctgt tatagaagct
    82261 gctgaggagt taaattctcc agtaatatta caaactactc catctactgt aaaatatgca
    82321 ggtcttgatt attatctagc aaatgcaaag gttgctgcag aaagagtaaa tatacctgta
    82381 gcaatgcatc tggaccatgg ttcaagtttt gaccttgcaa tgaaagcttt aagaagtgga
    82441 tatacatcaa taatgataga tggttctcat gaaagctttg aaaataatat atctatatct
    82501 aaatcagtag taaaagcatg tagtccttct cttataccag tggaagcaga acttgggaaa
    82561 gttggtggaa aagaagatga tttagatggc gggaatagta atgattatac aaatccaaaa
    82621 gaggcaaaag agtttgtcga tagaacagga atatcttcat tggctattgc tataggtact
    82681 gcacatggat tgtataaggg tgaacctaaa atagatttag ataggttatc agaaattaaa
    82741 aatgtagttt caataccttt agtattgcat ggaggttcag gaatacatga tgatattata
    82801 aaagaagcta taaaaagagg tattgcaaaa gttaactatg caactgaatt aagaattgca
    82861 tatagtaaag gggttaaaaa agttttagat gaagattctg aggttataga ccctaaaaag
    82921 tatggattag cagggcttca atcagtaaag gattttgtaa aagaaaagat taaagtgtgt
    82981 gggtctgtaa atagagtata aaaataaaat atcctaaatt tattttagat aagtttagga
    83041 tatttgttat atgaaaaatt tatattaatt atatgtaaat ggtgtatttt tttcatttaa
    83101 ttgatgaaa
//
LOCUS       DAEQAF010000006        70360 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.006, whole genome shotgun sequence.
ACCESSION   DAEQAF010000006 DAEQAF010000000
VERSION     DAEQAF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 70360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.006"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(43..1434)
                     /locus_tag="KRN00_000527"
     CDS             complement(43..1434)
                     /locus_tag="KRN00_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH1826414.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(1445..2665)
                     /locus_tag="KRN00_000528"
     CDS             complement(1445..2665)
                     /locus_tag="KRN00_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBH1826415.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(2679..3467)
                     /locus_tag="KRN00_000529"
     CDS             complement(2679..3467)
                     /locus_tag="KRN00_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003457975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1826416.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKDENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(3484..4758)
                     /gene="larA"
                     /locus_tag="KRN00_000530"
     CDS             complement(3484..4758)
                     /gene="larA"
                     /locus_tag="KRN00_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBH1826417.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSIDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(4876..5589)
                     /locus_tag="KRN00_000531"
     CDS             complement(4876..5589)
                     /locus_tag="KRN00_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH1826418.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            5714..6973
                     /locus_tag="KRN00_000532"
     CDS             5714..6973
                     /locus_tag="KRN00_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBH1826419.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            7241..7807
                     /locus_tag="KRN00_000533"
     CDS             7241..7807
                     /locus_tag="KRN00_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1826420.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKYLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(8008..9213)
                     /locus_tag="KRN00_000534"
     CDS             complement(8008..9213)
                     /locus_tag="KRN00_000534"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBH1826421.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SAKKLLKID"
     regulatory      complement(9316..9422)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(9514..9882)
                     /locus_tag="KRN00_000535"
     CDS             complement(9514..9882)
                     /locus_tag="KRN00_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBH1826422.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(9934..11211)
                     /gene="obgE"
                     /locus_tag="KRN00_000536"
     CDS             complement(9934..11211)
                     /gene="obgE"
                     /locus_tag="KRN00_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBH1826423.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRT
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(11322..11612)
                     /gene="rpmA"
                     /locus_tag="KRN00_000537"
     CDS             complement(11322..11612)
                     /gene="rpmA"
                     /locus_tag="KRN00_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBH1826424.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(11626..11943)
                     /locus_tag="KRN00_000538"
     CDS             complement(11626..11943)
                     /locus_tag="KRN00_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBH1826425.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(11958..12269)
                     /gene="rplU"
                     /locus_tag="KRN00_000539"
     CDS             complement(11958..12269)
                     /gene="rplU"
                     /locus_tag="KRN00_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBH1826426.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(12370..13791)
                     /locus_tag="KRN00_000540"
     CDS             complement(12370..13791)
                     /locus_tag="KRN00_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBH1826427.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGHDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(13809..14510)
                     /locus_tag="KRN00_000541"
     CDS             complement(13809..14510)
                     /locus_tag="KRN00_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBH1826428.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(14512..16356)
                     /locus_tag="KRN00_000542"
     CDS             complement(14512..16356)
                     /locus_tag="KRN00_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBH1826429.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            16675..17868
                     /locus_tag="KRN00_000543"
     CDS             16675..17868
                     /locus_tag="KRN00_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH1826430.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(18080..19162)
                     /locus_tag="KRN00_000544"
     CDS             complement(18080..19162)
                     /locus_tag="KRN00_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1826431.1"
                     /translation="MKKIRKLATKLLIAMMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(19726..20517)
                     /locus_tag="KRN00_000545"
     CDS             complement(19726..20517)
                     /locus_tag="KRN00_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826432.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(20521..20850)
                     /locus_tag="KRN00_000546"
     CDS             complement(20521..20850)
                     /locus_tag="KRN00_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826433.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(21334..21747)
                     /locus_tag="KRN00_000547"
     CDS             complement(21334..21747)
                     /locus_tag="KRN00_000547"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBH1826434.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(21788..22918)
                     /gene="rodA"
                     /locus_tag="KRN00_000548"
     CDS             complement(21788..22918)
                     /gene="rodA"
                     /locus_tag="KRN00_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBH1826435.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(23003..23287)
                     /gene="minE"
                     /locus_tag="KRN00_000549"
     CDS             complement(23003..23287)
                     /gene="minE"
                     /locus_tag="KRN00_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBH1826436.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(23305..24102)
                     /gene="minD"
                     /locus_tag="KRN00_000550"
     CDS             complement(23305..24102)
                     /gene="minD"
                     /locus_tag="KRN00_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBH1826437.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(24126..24809)
                     /locus_tag="KRN00_000551"
     CDS             complement(24126..24809)
                     /locus_tag="KRN00_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBH1826438.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(24907..27885)
                     /locus_tag="KRN00_000552"
     CDS             complement(24907..27885)
                     /locus_tag="KRN00_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBH1826439.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKMNVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(27897..28385)
                     /gene="mreD"
                     /locus_tag="KRN00_000553"
     CDS             complement(27897..28385)
                     /gene="mreD"
                     /locus_tag="KRN00_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBH1826440.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(28400..29293)
                     /gene="mreC"
                     /locus_tag="KRN00_000554"
     CDS             complement(28400..29293)
                     /gene="mreC"
                     /locus_tag="KRN00_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBH1826441.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(29303..30313)
                     /locus_tag="KRN00_000555"
     CDS             complement(29303..30313)
                     /locus_tag="KRN00_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH1826442.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(30434..31093)
                     /gene="radC"
                     /locus_tag="KRN00_000556"
     CDS             complement(30434..31093)
                     /gene="radC"
                     /locus_tag="KRN00_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBH1826443.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIMNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(31138..31722)
                     /gene="maf"
                     /locus_tag="KRN00_000557"
     CDS             complement(31138..31722)
                     /gene="maf"
                     /locus_tag="KRN00_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBH1826444.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(31942..32913)
                     /locus_tag="KRN00_000558"
     CDS             complement(31942..32913)
                     /locus_tag="KRN00_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBH1826445.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVGGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(32929..33504)
                     /gene="rsxA"
                     /locus_tag="KRN00_000559"
     CDS             complement(32929..33504)
                     /gene="rsxA"
                     /locus_tag="KRN00_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBH1826446.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(33519..34112)
                     /locus_tag="KRN00_000560"
     CDS             complement(33519..34112)
                     /locus_tag="KRN00_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBH1826447.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(34125..34694)
                     /locus_tag="KRN00_000561"
     CDS             complement(34125..34694)
                     /locus_tag="KRN00_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBH1826448.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDGLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(34694..35671)
                     /locus_tag="KRN00_000562"
     CDS             complement(34694..35671)
                     /locus_tag="KRN00_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBH1826449.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(35694..37031)
                     /gene="rsxC"
                     /locus_tag="KRN00_000563"
     CDS             complement(35694..37031)
                     /gene="rsxC"
                     /locus_tag="KRN00_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBH1826450.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(37247..38191)
                     /locus_tag="KRN00_000564"
     CDS             complement(37247..38191)
                     /locus_tag="KRN00_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826451.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(38302..39576)
                     /locus_tag="KRN00_000565"
     CDS             complement(38302..39576)
                     /locus_tag="KRN00_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1826452.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEDTKEKPNSSSN
                     QNSQSNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(39708..40079)
                     /locus_tag="KRN00_000566"
     CDS             complement(39708..40079)
                     /locus_tag="KRN00_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1826453.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(40307..40906)
                     /locus_tag="KRN00_000567"
     CDS             complement(40307..40906)
                     /locus_tag="KRN00_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826454.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(41107..41319)
                     /locus_tag="KRN00_000568"
     CDS             complement(41107..41319)
                     /locus_tag="KRN00_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBH1826455.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(41392..43107)
                     /locus_tag="KRN00_000569"
     CDS             complement(41392..43107)
                     /locus_tag="KRN00_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1826456.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(43107..43661)
                     /locus_tag="KRN00_000570"
     CDS             complement(43107..43661)
                     /locus_tag="KRN00_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH1826457.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(43654..44256)
                     /locus_tag="KRN00_000571"
     CDS             complement(43654..44256)
                     /locus_tag="KRN00_000571"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBH1826458.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(44265..46913)
                     /gene="polA"
                     /locus_tag="KRN00_000572"
     CDS             complement(44265..46913)
                     /gene="polA"
                     /locus_tag="KRN00_000572"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBH1826459.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKDYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            47065..47152
                     /locus_tag="KRN00_000573"
     tRNA            47065..47152
                     /locus_tag="KRN00_000573"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47099..47101,aa:Leu,seq:caa)
     gene            complement(47339..47782)
                     /locus_tag="KRN00_000574"
     CDS             complement(47339..47782)
                     /locus_tag="KRN00_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826460.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMCYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKRL"
     gene            complement(47785..47982)
                     /locus_tag="KRN00_000575"
     CDS             complement(47785..47982)
                     /locus_tag="KRN00_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826461.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(48174..49040)
                     /locus_tag="KRN00_000576"
     CDS             complement(48174..49040)
                     /locus_tag="KRN00_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1826462.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(49266..50135)
                     /locus_tag="KRN00_000577"
     CDS             complement(49266..50135)
                     /locus_tag="KRN00_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1826463.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(50641..50862)
                     /locus_tag="KRN00_000578"
     CDS             complement(50641..50862)
                     /locus_tag="KRN00_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826464.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(51363..52343)
                     /locus_tag="KRN00_000579"
     CDS             complement(51363..52343)
                     /locus_tag="KRN00_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826465.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(52507..53379)
                     /locus_tag="KRN00_000580"
     CDS             complement(52507..53379)
                     /locus_tag="KRN00_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1826466.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(53543..54094)
                     /locus_tag="KRN00_000581"
     CDS             complement(53543..54094)
                     /locus_tag="KRN00_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1826467.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(54114..55016)
                     /locus_tag="KRN00_000582"
     CDS             complement(54114..55016)
                     /locus_tag="KRN00_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH1826468.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRAQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(55031..57403)
                     /locus_tag="KRN00_000583"
     CDS             complement(55031..57403)
                     /locus_tag="KRN00_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBH1826469.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPDEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(57624..58313)
                     /locus_tag="KRN00_000584"
     CDS             complement(57624..58313)
                     /locus_tag="KRN00_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1826470.1"
                     /translation="MKVKRNINRVAIIVALNLSLALMVGCMSPVSDKNLSSSEQISKD
                     SLKEQVEDKKDESIELFNNYSQKINDAKGREEVKKDLSQRFSKAIIDSGYSITNSKSD
                     GSFVVSINGAEKPPEKNIRSLFYSMSEDDKEGKVTIDILCAKEYPEDDKLSESDKYVK
                     FIYNLFKSLTDTNLTEKEIFSMVEEDFNKGVGVVELPYMKDIHVEVNKVKQSTKVLKL
                     SLVYKFDISNH"
     gene            complement(58554..59933)
                     /locus_tag="KRN00_000585"
     CDS             complement(58554..59933)
                     /locus_tag="KRN00_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1826471.1"
                     /translation="MLNFMTELLVVLSIFIQFSIMNGILIYKKDSKKNEKIVFYIVLF
                     LIYIIIQISRLFNGGNYFSNINYLFYILAFIAWGGYYNYFYKMGYIKYSIFFYLFSVY
                     YKCLDAVIYRILFFAITGNVISSKESLLVPHLESIKIQIYSNLIIILIYLIFSFFRKS
                     IKLISQDKRNYVYLLFALLVNTMNMLVNYVLKKLERFGSLHSEGYYFDNFVNPKLVGA
                     SSIFLILLFKEIIKENRLKSQAELIKNKLDMQYAHYLSIQESHMRVKKLYHDINNHIY
                     CIDNLRNNSKEINEYVNNLKDEIKTFKYIYNTGNMILDIIINEKSEVCLKKGIKFTCS
                     INFSKVNFVKPIDVSSIFSNILDNAIEACDKIVDENINKYIRIKGTITRSFFVLKCEN
                     SKLNQLTFNKNILLTNKMDKFVHGIGIQSIKSSLQKYNGELLFENSIDKFILNIYIPL
                     DQDTDSWGD"
     gene            complement(59927..60640)
                     /gene="rgbR"
                     /locus_tag="KRN00_000586"
     CDS             complement(59927..60640)
                     /gene="rgbR"
                     /locus_tag="KRN00_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBH1826472.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNTAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(60890..61450)
                     /locus_tag="KRN00_000587"
     CDS             complement(60890..61450)
                     /locus_tag="KRN00_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBH1826473.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSILFMNMFIFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYAVQLYRRLMYYLRLKKFK"
     gene            complement(61546..62349)
                     /gene="zupT"
                     /locus_tag="KRN00_000588"
     CDS             complement(61546..62349)
                     /gene="zupT"
                     /locus_tag="KRN00_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBH1826474.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(62500..63663)
                     /locus_tag="KRN00_000589"
     CDS             complement(62500..63663)
                     /locus_tag="KRN00_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1826475.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAVLEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(63723..64910)
                     /locus_tag="KRN00_000590"
     CDS             complement(63723..64910)
                     /locus_tag="KRN00_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826476.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(65273..66973)
                     /locus_tag="KRN00_000591"
     CDS             complement(65273..66973)
                     /locus_tag="KRN00_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826477.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNGMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(67228..67503)
                     /locus_tag="KRN00_000592"
     CDS             complement(67228..67503)
                     /locus_tag="KRN00_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1826478.1"
                     /translation="MKKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECS
                     TKQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
     gene            complement(67622..68194)
                     /gene="mobB"
                     /locus_tag="KRN00_000593"
     CDS             complement(67622..68194)
                     /gene="mobB"
                     /locus_tag="KRN00_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBH1826479.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCIKNEILSISNVEIKNILKE"
     gene            complement(68178..69359)
                     /locus_tag="KRN00_000594"
     CDS             complement(68178..69359)
                     /locus_tag="KRN00_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBH1826480.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            complement(69570..70304)
                     /locus_tag="KRN00_000595"
     CDS             complement(69570..70304)
                     /locus_tag="KRN00_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826481.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
BASE COUNT        22094 a        13019 c         7420 g        27827 t
ORIGIN      
        1 tttaatattt tttgttttat aaatattatt aaattaatat ttctaatata ttttccctgg
       61 atttaaaata tttttagggt caaaagctaa ctttatattt ttaattaaca tcatataagc
      121 atctgaattt gattcatgta agtactcttt tttagcatat cctatgccat gttcaccaga
      181 aacttgacca ctaagttctc tagatttttt atacatatag tcaaaagttt cttttaatct
      241 tattttccat gtattatcat ccataccatc ttttaaaata tatatgtgta gatttccatc
      301 tcctgcatga ccaaaacttt ttattcttat ttttaatttg tcttgaagct cgtgagtgta
      361 tcttataaac tctgctatct tatctcttgg aacaacgaca tcacattcat ccatttgtgt
      421 cgtagatgcc tttatagctt ctaaaaatgc acctctggct gaccatatag aatcgtttct
      481 ttcttgtgta tctgatataa atacatctaa tgcaccattt tctaaacata aattagctac
      541 tttttcatat tctttttcta tatcttcagt gctatttcca tcaaatgtaa gcaaaagata
      601 agcatctgat gtattatctg gaaacttttt acctaaaaat tcttctgctg ccaatattac
      661 atctctttcc ataaattcta tagccgttgg tattgatttt gattttatta ttttaggaac
      721 agtttctatt gccattgata aatctggaaa tggtataagc aaacttatac ttttctttgg
      781 taaaggaagc aattttaata tagctttagt aactattcct aaagtacctt ctgagcccac
      841 taataaatcc tttatactat atccagaact atttttaacc acctttccac ctacatttat
      901 aatttctcca tttggtagta caacttcaag acctcttaca taatcccttg taacgccata
      961 ttttactgct ctcataccac ctgcattagt gtttatatta cctgcaattg tagcactttt
     1021 ttcacctggg tcaggtgggt aaaataaatc tctatcttga acatattgac ctattgtcat
     1081 caataaaaca cctggttcta ctgtcaatgt taaattttca taatcaactt caagtatttt
     1141 attcatttta catagattaa tcattattcc accatttatg gcaacagcag cacctacaag
     1201 accagtacct tgacctcttg gtgtgactgg tatattattt ttatatgcgt atttcattat
     1261 tttagatact tgttcagttt caagtacatt tactaaaact tcagggtact tctcaatccc
     1321 tccaagttca tcatgtgaaa aatcttcatt tatatcactt ccaactaata cattttcttc
     1381 tccacaagta tctattaaaa aatctatatc ttttttatcg attaatttat acatttctat
     1441 ccccctattt agctgctgat gccatatatt tttgattatt atctttgtta ttttctattt
     1501 tttcaatcaa tttaggaata atatcataaa tatcacctat taaagctaga tgtgctacat
     1561 caagtatagg cgctttatca tctttattta ttgctactat atagtcagca ccctgcatcc
     1621 ctgcaacaaa ttgaacagct ccagatacac cacaagttat tatcaattta ggttttacag
     1681 ttctaccact aagacctatt tgttttttag catctatcca acctgcttct attacaggtc
     1741 ttgttcctgc cacttgagcg tttaacttat cagctaattt atatatcatc tccatatctt
     1801 cttgtttttt tattgctcta cttgccacaa ctatcacttc agcttcttcc agaccaactt
     1861 ctttattttt ttcttttaca ctcagtacct taattttaga ttttagttct tttttttcta
     1921 ctttacataa agttatcttt cctgtagtat tctctatttt ttctggtgct gaaaatattt
     1981 tatatcttac agtggcaaat tgtggtctat tattaggtgt gtttatatga gccattatat
     2041 ttccaccaaa tgctggtctt atttggtcta aatcagtatt tgattgaata tcaagtattg
     2101 tacaatctgc tgtaagacct gttctaaatc tagcggcaag tcttggagct aatgacctac
     2161 ctaatgtagt tccaccaact aatactatcg ttggttttat tttatctata aagttttcta
     2221 ttgcttttga atatggttct atcctaaaat ctttaaattc atcttcatca tatacaaata
     2281 cttcatccac cccataagaa atcaaattac tgcacttatc ttttatgtct tttcctacaa
     2341 atacacaata cacaggttgt tttatttttg atgccatctc acgagcttta cctataagct
     2401 cgtacgttac aggatgtata tttccattat gatgttcaac atatactgca attcccctcc
     2461 attcatcttt attaatttgt actttactac tctctataaa ttcaaatgcg ccttttggtc
     2521 cacttttgac acacaacttg cacatcttac agccagcact tatttctact atacctgact
     2581 tttcttctat agccccaaaa ggacatattt ctaaaattct ctttaagtca gttattttat
     2641 cttgatttac aactatcttt gacatttatt actccccctt acaccaactt taattcctct
     2701 aatttattta caagtgcaaa acttagttca tctgcatttc ctcttacaat atttttatct
     2761 gtatttggct ttggaggaaa tattcttaca acttgagtag gagaaccatt aagtccatag
     2821 ttattttcat ctttatcttc aaagtcatct aagctatata caggtatttc tctatcttta
     2881 gtattaagtt ttaatttaaa tgaaggtagt cttggttgaa aaatgtcttt ttctacagtt
     2941 attaaacatg gatattcaat ctcacatact tgtaaatcat ttggcatatc tatttcaaca
     3001 actatacttt catctttaac ttcaattaat tttgtaacgt tagtaacatg aggtatatct
     3061 aaaaattcag ctacttcagg tcccacctgt gctgtatcac catcagtagt ttgttttcca
     3121 caaattatta ggtctacctt tcccatcttc ttaatacctt gtgatatggt ataggaagta
     3181 gccaatacat ctgctcctcc aaatctccta tcacttatta atgctccttc atcagctccc
     3241 atcataaaac tttcttcaat taccttcttt gcctgaggag gacccatgct aagtactttt
     3301 agattcgctt tcttatcttc ctttattcta agagctgttt ctaaagcata taggtcatag
     3361 ggattcattt ttgaatctac tccatctctt tttagtactc ctgtagtttc atcaacttct
     3421 actgaagtcg ttccaggaac ttgtttaata catgtcaaaa tttccataaa gtacactcct
     3481 tttttattta actataactg atactccatc aggtataact actactttgc tctccttacc
     3541 aactatacta ttcgccattt ctaaagcttc tttaaagtta aatgcatgtt tcatatgcat
     3601 tttttttatc atttcaggat tacacttatc tgttaccatt atcacagtat atttagataa
     3661 tattctcgct agtatctgaa attcccattg gtctggaatc gtatctactc tatcgatact
     3721 tctaatttta tctaaaagtt gttttggaga atctgcattt gctacatttt cataaaaaga
     3781 ttgacctcca tgaccatcat tacatgctga aatcattatt attactccac cgtctttaca
     3841 agtagcttca gctgctgtca ttcctttaac agattgataa atattttggt ctagtggata
     3901 tccaccattt gtagttacaa caatatcaga ttttatagaa tttacttttg ataactctgt
     3961 tacaaatcta catcctttag tatgtgcttt ttcgacatca ccagcaaagg aagcaattat
     4021 ttttttatct ttatctatta caacattcaa tatgaatgct aattttgcaa ctttagcagc
     4081 atataccata tcctcatgaa taggattatt attcaatttt ccagttcttg aattgtcact
     4141 atctataaag tcactacagt gattgtacat tatagtcttt gcagatgcga ttcctggaag
     4201 tacgcttttt ctgccacctg aaaaacctgc aaagaaatga ggttctataa aaccttctgc
     4261 tatcaaaagt tctgcctcat atgctagttt gtttatatat aaatctccac ctgaaggcaa
     4321 tatccctact ttacacatag atttatcatc agtagatata tgcataacta tatcttcatt
     4381 atctactatt tcttctccca ttttataaat tagctcttcc cttgtacttg gcctatgaaa
     4441 tccagttgcc actataatct tcacatcaat ttctggatta acattcctaa tccttcttaa
     4501 tataattggc atagttattc tacttggtac aggtcttgta tggtcacttg taattatgac
     4561 tacattcttt ttccccttaa ccagttcttc cagagaatta gagcctatag gattattcat
     4621 agattcttca actatctctt cttgagtctt atgttctata taattatccg attttgactc
     4681 caaaacaccg agaaaacgtt catcaggtat ttctaaaatc attccttgtt ttgaatacgg
     4741 tacttttaac tttaccattt ttaatctccc attataataa actataaaat tggtatgtgg
     4801 tcataccagt tttacattta tataatagta ccattatcta ccatttgcaa gaataattta
     4861 ttttataaca aacttttaat tttcattttt tctataattt ttacttataa aatccatatg
     4921 ttcctttgct ttctcacatg caagttctac atcattttct acaactgcat tgtatatagc
     4981 ttcatgctgt ttaagcaata tattttcatt aaaaggttct gcgattattt tttctcttgc
     5041 atcttctata aatccatcaa ataattttga tgctgtcata aaaagacttt gaattaaata
     5101 atttttactc aatgttgcta gtttactgtg aaatttttgg tctaataaca ccagtactcg
     5161 attattatct tttttattag tttctaccct catttcatct attatatgtt tcaattctat
     5221 aacttcagaa gaagttattc tctttgaagc aagttttgca atctcaattt ctaggattat
     5281 tctaagctct aatatatctt caagtgtacc attattaagt ttaaaaatca tagataaagg
     5341 ttctattaaa gttttttcta tatttgtaca tataaaattt ccttcaccct gtctgctttc
     5401 tatcactccc atagtctcta ataccctaat agcttccctt atggaagttc tactcacatt
     5461 catttgttca gacagttctc tttctgatag taatttatcc ccctttttta actctccatt
     5521 tagtatttta tattgtattt gctcaattac ttgttcataa acttttttac tagctatact
     5581 attaaacatt ttttcctcca atatgataat cgttgttgta atatatatct attatatatc
     5641 ttaagccatt acattcatat atttttatta cttttaatat aatatcttat aactcaaatt
     5701 tacaggtgat attatgaaaa aaaataaaat tattgctttt tttgctccat ctatcatagt
     5761 tggagttcta gttttaggga ttatcctata cccaaatgaa gctataaaat ctgcaagaga
     5821 aggcttttct atatggtcta atgttttagt tccatcacta ctaccattta taattggagc
     5881 aaacttaatt gttgatttaa aaatagtgga tattataggg tttatcatca atcccataac
     5941 tagatttgta tttaatgttt caggaaagag cgctttagct tttgctatat ctacagtatc
     6001 tggttatcca gtaggagtaa gtttagcttc tgaatttagg agtaatggac aaatttctaa
     6061 gtatgaagca caaagacttg tgtctttttg ttctacatca ggacctttat tcataatagg
     6121 ttcggttggt acaggtatgt tccaaaattc aaacttaggt tatttaatga ttctctgcca
     6181 ttatctagga actatattgg ttggtctttt ctttagaaat tatggtaatg aaaatcttcc
     6241 aaagacaaaa ttggatttaa aaacaaatat aaaaaatgta atcaacatta gaaattcaag
     6301 tgggaatggt ttttttgttt tatttggaaa tgctgtattt aatggagtaa atacattact
     6361 tacagttggt ggatttgtaa ttgttttttc agtagtattt aaaatactat ctctttttaa
     6421 tgtaatctca ttaatagcat cagttatata tttgcctctt tcatttttag gtgttagtaa
     6481 agaactctgt caagcatttg taagtggtct atttgaaatt actataggat gcaataaagt
     6541 atctagtata acaagttctc cagaaatttt aagagcatct ttagctagtt ttttgatagg
     6601 atttagtgga ttatccatcc tagctcaatg ttgtacattt ctatcaaaaa cggacataga
     6661 tttaaaatta tacatactaa gtaaatttgc gcatggagtt ttagctgcta tctttatatt
     6721 tatactttat ccaattgcaa actctgctgt gttggtttct agctttgctg atacatacaa
     6781 cgttatatat aataatttaa tctggtttta ttatcttagc tattatgata caattcttca
     6841 aattgtagta ataatttatc taatctcagc cgtatttatt gcaaaaaaac atatgaaaac
     6901 tttatctaca aatgggaaac taatgcgata taaaaatact tttttcacta agaaattttc
     6961 acgaaaaaaa taaaactaat aaaacttaac taaatacttc cattttttta ttatatttgt
     7021 cataatttta ataacctttt taattagttt aacagcatag ttatttcatc acaatttaat
     7081 aattttatta gaaatatttt tcaaaaaatt ctccttaatc acatatatca cacttgtata
     7141 agtttactgg taaatttttc cattatataa tatttcattt atattatata ataaataccg
     7201 acctaaactt accaaatcaa actaagagga gtggttgaaa atggcaacaa gacctataga
     7261 aatagacgaa tataaaaaga taatggaact attacatact ggctttactt atagtgaaaa
     7321 tggcgttgaa aaaagattta gaaaaaatcc taaagttgca ttggcactaa tgttagaagc
     7381 taatttaggt ctaagaatat cagatatttt aagattaaag ataggtaatt ttaaaggtaa
     7441 tatgttggaa ataaatgaaa aaaagacggg caaattacag tatagaccag ttaataaaaa
     7501 tataattgag tccataaatg aacatgcaag aaagtataat cttaaatcaa atgactactt
     7561 agtaaatata aagacaaagg ctattcaaaa acagttgagg ataatttgta aatacttaaa
     7621 tctgtataat ataagtacac atagctttag aaagctctat gctactactc aatttgaaaa
     7681 gagtaacaat aatttagagt tggttaaaga acttttaaat cacagctctg tagccactac
     7741 acagcgatat ataagggtaa ctcagcaagc tattaatgaa gctagtgaaa atttctttat
     7801 tggttaatta taacgtatac atttttctat tatcttatta attcaccaga tattaaaaaa
     7861 gagtgtctta aaatgaactt tttagttcat gagacactct ttttttataa aatcaaatat
     7921 atttttatta tttcaacact ggaaaaaagg cttatctctc tattttgaga caccctatta
     7981 aattttcata attcttgcat aaacatatta atctatcttc aataattttt tagctgattc
     8041 actgtaatta tttcttttta caatttccaa aactctatca atctcatgtt ctgactttgc
     8101 acttacaaaa atcgccaatt cttcatcatc tataatatca taactatcta catatttatc
     8161 taaacattct aaaattccat ctttattatt atacccacca aatctaacta ctgcactaca
     8221 ctcatcttct ataagtccac ttaaatccaa tttccctttt gaaaaagact ttatatttga
     8281 actcctatta tctattatat ctataatatc tgcataaaca gcacttcctg ttgcacctct
     8341 tccagctccc ttacctacaa aagaaagttc acctactgaa tcacctacta aaataactac
     8401 gttgaactca ttatctatct ttgaaagcat attattattg tccactaagg ctggtctaac
     8461 aaatccactt acttctcctg attcatactt acttctagca accaatttta tcttacaatt
     8521 taattttttt gcatattcta tatctttttc atctattgaa gttattcctt ctaataataa
     8581 atctttccaa tatactattt ttccataaga taaagtagac aatatagata actttctagc
     8641 actatcatat cctaaaacat ctgcatctgg attaacttct gcaaatccca actcttgtgc
     8701 ctgttttaaa gcgacatcat acggtaaatt ttcatcatac atctttgata atataaaatt
     8761 acaagtccca tttaaaatag cgtttatgct ctttatattg ttgccttcca gtgattctat
     8821 caatggtttt aaaactggaa taccacctgc cacagatgct tcaaacttga tgctaacatt
     8881 atttaagtta gctaattcta taaggtcact acctttttca gccagtaaat ctttattagc
     8941 tgtcactaca tgtatttttt tatttaacgc tcttgttaca taatcaaaag ctggatttaa
     9001 tcctccaatt acttcaacta gtatatcaat atccttgtca aatatatctt ctatatcagt
     9061 agttatctta tcaaaatact tcttatactt gtgtttttct ttatttttaa ctaaaattcc
     9121 aacaacttct atatctcttt ttgaagtatt attttctatt aaatcaatta atccacttcc
     9181 tactgttcca taccctaata ttgctatctt cactgtaaca tacccccatc attttgatta
     9241 tattaaatta tttatatata taaatatacc aataaaaaaa gcttgagtat aaactcaagc
     9301 catatgacgg gtttatactc atctttcagc ataaatgctg caggatttag caccaatgta
     9361 taattaaata tactggttgc cgggcttcac agggccagtc cctctgccac tcttgataag
     9421 attgctaatt taaatttatg tttaatagta taatacaatt tcttccaatt gtcactattt
     9481 ttttaactta tttccctaaa aggatataaa ctattatcta acagctcttt tagttggttt
     9541 accctttttt gtaacattat tatttttagt ctttgccttc gcctgttcat gtcctggaaa
     9601 aagtatttta ggctcttcaa tattcctctt gtaaatagta aatttaaaac caatagcctg
     9661 cacaaattca gctcttaaag cttcacatac tgcattagca gtttctttag tatcaagacc
     9721 tgcattttct aatatagtaa cttttactaa ttctctagtt cttaacatac catctaattg
     9781 ctctaagaaa ctctctgtaa caccttcttt accaatttgt gtagtaggct ttaaagtatt
     9841 tgccaaagat cttaaatacg ccctttgttt tccttttaac atattctcac ctctataatt
     9901 ctatacttaa attatctata atctatattt aaattaattg taaaactcaa attctaattc
     9961 ataaatttta accacatctc catcttctat tcccatttct ctaagcctat caaaaacacc
    10021 ttgactctcc atagcttttt ggaaatattg aagggattcc atatcatcaa aatttacaga
    10081 atacattatt cttctaagtg ctttacctgt aactacatac acaccatctt caatatctat
    10141 acttaactct tcttcagtac caatatcaag ttctggtcta tacatttctt cttctgaaac
    10201 tagctccaca tcttctactt cttttagcat tttagaaaca taggctatta cttcatctat
    10261 gccttgacga gttgctgctg acattttaaa tactgtatat cctctgcctt ctaattcact
    10321 cttaaacttc tcaaacttac tctcatcttc taatatatca aatttatttg caactacaac
    10381 ttgtgttctc tttgaaagct tttcattgta caatttaagc tcatcattta tcttgtcaaa
    10441 atcttcaata gggtctcttc cctctaatcc agatatatct acaatatgta tcaatacctt
    10501 tgttctctca acatgtctta agaactcatg acctaatcct atgccttcag aagcaccctc
    10561 tataattcca ggtatatctg caagtacaaa actatctcca aacttagttt gaacaacacc
    10621 tagatttggt gtaagtgttg taaaatgata gtttgcaatt ttgggtttag ctttagttac
    10681 aactgataga aatgttgatt tacctacatt tggaaatcct aaaagaccaa catctgctat
    10741 cattttaagt tcaagagtta tccatctttc ttctccatct gtaccagatt ttgcaaaagc
    10801 tggagcttgt cttactgcat ttgcaaagtg ttggttacct ttaccaccta taccaccttt
    10861 tgcaactata gctgtatctc cttctttttt taaatctgct aatacaagac ctgtagcctc
    10921 atctcttatt actgtacctg ctggtacttt taatactaaa ttttctccat ttttaccagc
    10981 tctttttcct ttgcttccgt cgccaccatt ttgagcttga tattttttct ggtacttaaa
    11041 gtccattaga gttctaagcc ccaaatcaac ttcaaatatg atgcttgctc cacgaccacc
    11101 atctccaccg tctggaccac cagctggaac gtatttttct cttctaaatg ctaccgaacc
    11161 atttccacca tttccagcct taacaaatat tcttgcctta tctataaaca aattcttcac
    11221 ctacttaatt aaaaactttt aattagcatt accaaaaata ccattataaa ttcatcagta
    11281 ttataagaaa aaggagtgcc tcaacactcc ttttatgtat attactcagc tattgctact
    11341 ggatatatac taactttttt tctcttcttg tcttttcttt cgaatttaac agtaccatca
    11401 actaatgcaa ataaagtatc atcactacct tttccaacat tagttcctgg atgtatttta
    11461 gttcctcttt gtctaactat tatacttcca gcagttacta attgaccatc aaatctctta
    11521 acacctaatc ttttagatat agaatctcta ccatttttag aagaacctac ccctttttta
    11581 gatgctaata attgtaaatt catgtttaac atatggagtc accccctact tttttaaaat
    11641 ttttatattt tttgggtatt cccgtttaat ttctttaacc gctaattgaa agtgatttag
    11701 taataattgt gcgtctttta catgtgtatc tttgactata cactctatat gaccttcttc
    11761 tcctactact ttttcaaatt caatcttttg taatttgtct aaagaattta taactgcaat
    11821 agcattagat gtaactgcag cacatactat atcatagcct atttcagcaa aatcagcatg
    11881 tccctttaaa caaaaacctt gcaacaagaa atcatcatta taataatatt taacttttat
    11941 cataacttaa ccaataacta agcgtttatt ttttctacaa ctatcttagt gtatgattga
    12001 cgatgtcctt gttttcttct gtaatctttt tttgctttat acttgaaaac tataactttc
    12061 ttagctttac cttgttcaac aactttagct tgaacagatg ctccttctac tactggagaa
    12121 cctaatttta attctccatc tttagagcaa gctaatactt cgtttaaagt aacaacatca
    12181 cctgcgttag cttctaattt ttcaacgaat aatacatcac cttcagaaac tttatattgc
    12241 tttccaccag tctttactat agcgtacatt aaatacacct cctcggcctc aaactcgcca
    12301 gtacaaggta cttcatttga agatttaaac ctttactgtg cggcattaca attattaatt
    12361 ataaaatatt tacattttat tgtcaactat tttatcgaaa ataacattgg ttttattgtg
    12421 ctttaatgta ctatttgcgt ttaaagaaat ctttatatta tatttttcac caattttatc
    12481 aattatatcc atataatatt cttttatttg ttcaaaaata aaatcattaa attctaccat
    12541 tatgtttttg taaacagtat gttcacttat tctcataatt tctttttcaa tactatctag
    12601 tatataatgt acagatttta ttgtttgttc accatcacaa catggacaag acattaaata
    12661 atacttatca atggattctt tttctctacg cctagcaact tctactaaac caagttttgt
    12721 catacctaat acttcagctt ttcttttatc tttattaaat tcttcttcta ggatgtgtaa
    12781 aatctccttt tgatgcttct ttttatgcat atcaataaaa tcgattatta ttatcccagc
    12841 tatgtctcta attctaagct gtcttacaat ttcttttgca gcttcaagat tagttttata
    12901 aacggtttca tcaagtttac cagttccaat aaacttaccc gtatttacat ctataactgt
    12961 aagagcttct gttttttcaa ttattaaata acctccactc tttaaccata cttttttatt
    13021 taataatttt tctattttag attctattct gtataaatca aatacatctc tattttcctc
    13081 aagacacagt ttatcaacat aagtcttatc tatacctctt aaaatagact taagttcaga
    13141 gtacttatca taactattgg taattataga ttcaatatca tcattcacat tatcttttac
    13201 atatttagtt gcaaaatcta aagacttata taataatttc ggacctatac caagtttata
    13261 ttcttttaaa atgttttcat actttaattt caactcttct atatctttct ttatttcatc
    13321 atgagtgcaa ccttgagcct cagtccttat tattaatcct agattttcct tatttactgc
    13381 cttagtaatt ttttttaatc taaatcgttc tttttcatca gtaattttat ttgatattgt
    13441 agttctatca ttggaaggta tatagacaat ataccttcca gaaatactaa tctcagtgtt
    13501 taattttgcg cctttagttc ctatttcttc tttatttatc tgaaccaaaa tatcgtgacc
    13561 agattttata gtacttccct tttttaattg taaataagca agtttcttaa atccaatatc
    13621 tacaaaacaa gcttctattc ctggtataac tttttttacg attccacgat atatattgga
    13681 tacagtcttc ttatttaaat tgtcttcaac aaaaagttct gttaatcttt catcttcaag
    13741 tactgctgtt ttctgggacc ctattaggga ctcaataact atctttttca caacttcacc
    13801 tctcgagctt acataggagt cactaattcc ccatcttcta atacatataa atctcttctc
    13861 aatatatcaa catctaatgg gtcaatatca agttcaaaca tctctaatat ctttggtata
    13921 agtatattag tatttaaatt agtttttgag cctgtagcta tagtagcagt aagagtaata
    13981 tgttcatctt ctaaatttaa aacatcaaag gttcttatca taggtcttat atctacttca
    14041 accatcttac cttttttatt cttttttgtt atgattattt ctttattatt cataaagtca
    14101 attacttttc tttttacaaa ctctttcgtc ataggtcttt tcaaatctat attaaacaaa
    14161 tattctccat agtctatcac agaagaaaga gaaggtgttt gtctatcaat ttcttttgct
    14221 ttgataaaat ctatcccatc tggaagttga attgatactt tatttaaaaa ttcctctact
    14281 gataaatcat cttcttctat ttcaatatct acatactcac cttgactttc tgtccctaaa
    14341 gccaaagcat tgccataact cattttaggg tgaggattaa atccttgaga atgtgataag
    14401 tttatttcag ctcttctaaa cgctctttgt aacaatctct gaaggtcaag atgtgatata
    14461 tatatcatgt cgccttcctt tttaaatttt actcttatta tcttactcat attagcaaag
    14521 cccccttcct atatcatgta tatttattcc acaaccattg cagttatgtc tacaatcaga
    14581 agtgattttt tcttttttag cattttcgtc ttctctaatt aagaattttt tactaatacc
    14641 tacatctata tggtcccaag gaaatacctc ttcatagttt ctatttctat gtgcataaaa
    14701 atctatagaa agattattct tttccatagc ttctttccat atatctaaat taaaatgttc
    14761 tgcccatcca tcaaatttag cacctagtct aaatgcatca tatataactt ttcctattct
    14821 tctatcgcct ctagctacta ctgcttccat caaactagtc tttgaatcat gataattgta
    14881 ttttatattg ttatttctta atttatttac taaatgtctc tgcttattaa taacttcttc
    14941 tgtagtatct tgaccatgcc attggaaagg tgtaaatggc tttggtacaa atgtagaagt
    15001 actcactgta acactaaaac ttctctttag ctttcctcca tttacttttc tataaatatc
    15061 aataacttta taagctaatt tagctatacc atctaaatct tcataagtct cagttggtaa
    15121 accaatcata aaatacaact taacactatt ccaccccatc tcaaaagctc tttctgttgc
    15181 attttccaaa tcttcttctg taacaccttt atttataaca tctctaagtc tttgagttcc
    15241 tgcttctgga gcaaaagtaa gtccagattt tcttacttgt tgtattttat cagcaatttc
    15301 cattgaaaaa ttatctaatc taagggatgg aagcgaaatc ccaatattat tagatgcata
    15361 ttcatctacc aaataatcag tcaactctga taacttacta taatcactcg tactaagtga
    15421 tgataatgat atttcatcat atccagtatt cttaactaat ttatctaata tttctttaag
    15481 tcttttaaca ctcttttctc ttattggtct gtatatcata cctgcttgac agaatctaca
    15541 tcctctagta catcctctaa ataattctag tactattcta tcatgaacag tatctatata
    15601 aggtactatt agtttttctg gataatctac agtctcaaca tcttttatta tccttttagt
    15661 aggattttta gtaatccctt ctctattagg agttacactt tgaactgtac catcttcatt
    15721 gtacttgaca tcataaaaac ttggtatgta tactccttct atgctagata ttttatataa
    15781 aaaatcttct ctagtcgttt tatttttctt ccattcttta tactcattta ctacttctaa
    15841 attaacctct tcaccttcac ctaatattac tacatctaca aaatctgcta atggttcgga
    15901 attataagca caaggaccac caaccattat aaatgggtct tccaaagttc tttcttcttt
    15961 taatattggt atattggcta aatctaatat atttaagata ttagtgtatg aaagttcata
    16021 ttgaagtgta aaagtgacaa aatcaaagtt tgttataggc tctcttgact ctaatgcaaa
    16081 taatggtata cttttttctc tcattatatt ttccatatca actgcaggag aatacactct
    16141 ctcacaaaat acatcttcat ccttatttat tacatcatat aatatatgac tccctaagtg
    16201 actcatacca acttcatata aatctggaaa gcaatgtgca tatcttatca attcactatt
    16261 actagtatct ttatgaattg aatttatttc atttccaaga tatctagcag gcttttctac
    16321 tttttttaag atttttttca agtctacttt attcatttat taaaattcct ccaaacaagc
    16381 tctttatttt tattcttatt tataagtaat attatacacg ataaaatatt ttctatcaaa
    16441 aatataacta aaatattgaa tttaaaatac atattattca caaaatagaa tagctaaaaa
    16501 tatttaagaa tattttctat taaattttta ttgaaataca atttttttac aaagtatgat
    16561 atattataaa cataaaacta ttgttttaca tgacttatca tgacatcttt tgtttcattc
    16621 acctcaaaat ggggtatgtt acttatataa tgataaattt taggagggtt aaaaatgagt
    16681 aaagtttttg aagtaaaaaa agatatctac tttactggcg tagtagatga aggtttaaaa
    16741 gtattcgaca taataatgga aactgagttt gggacaactt acaactctta tttaatcaag
    16801 gacgaaaaaa cggttttatt tgacactgta aaggcaaatt ttaaagatga gtttttaagt
    16861 aatttatcag aggttactga tatagctaaa attgactatg ttgtaattca tcacacagaa
    16921 ccagaccatg caggtagttt aaaatactta ttagatataa atcctaatat agaagtttat
    16981 tgtactaaag ctgctaaact atacttagat ggtcaaataa atagaccttt taactgtcat
    17041 gtaataaaag atggtgaaat tttaaatatc ggtaaaagaa atcttagatt tataactgct
    17101 ccattcttac attgggttga tacaatgttt acttacattg aggaggacaa gactctttta
    17161 acttgtgatg catttggttg tcactttgca agtgttgatg cagaggtagt gaatagtgaa
    17221 gattatctaa aatcagctaa acactactat gattgtatag ttaagccatt tgctaaacat
    17281 gttttaagtg ctgtagataa ggtggtagga ctaaacatag aatttgatac tatattgact
    17341 tctcatggtc caatgcttac taaagaccca atggctgctg ttaaaagata tgttgagtgg
    17401 tctacagaag ctgttaatac aactaatcaa aatcaagttt ctatattcta cttatcagct
    17461 tatagtaata ctttagagat ggctaaaaag ataaaagaag gacttgataa agaaggtgca
    17521 aaggctgaat tatatgattt agaagatatg acattaacag aaatgcacga tacattagta
    17581 gtgtcaaaag taatattact aggctctcca actataaaca aaactatggt taaacctatg
    17641 tgggatttat tctctgttat agacccaatg gctaaccaag gcaagatagc aggagtattt
    17701 ggttcatttg gttggagtgg tgaaggtata actatggctg agactttact taaatctatg
    17761 tcattcaaaa tgcctgtaga atctcttaag aaaaaattct tccctagtga agagacatta
    17821 aaagagtgta tggcatttgg tgcagaattt gcaaaattag ttaaatagcc attaatcaca
    17881 cataatatta tttaaaataa atgattttat atttaaaaat aaattaaaat ggagttgtct
    17941 caaaattaat ttttctaatc taattttaag ttcaactcct ttttcatttt ctaaaatgac
    18001 tgatataatg ataaatgcac cctttgtgcg agggtgcatt atttataata tgttctattt
    18061 gtacactagt atatttgtat taattcacat atctagcgta tgctaccatc cctcttccag
    18121 aattagatgc cgtttcacca atttccactt taataattac attattttct ttacactttt
    18181 ttgataattc tgctgcagaa aggttcttac cagtaaaatc taaagaaaat ggcttatcat
    18241 attcaaaagg atactcatca ggtacaccat ctggagctaa tgcaaccata ccatatggtg
    18301 tattcataaa ccctattaca gtaactgtat gctttgatgg gtctaaattt gaatttttgc
    18361 ttgtaaactt aattgtattt attgatgagt tgattaaact acacggaact ccctcataca
    18421 tttcaatttt tggacgtaga ttatttccat aaacttcatc aagtattgcc ccttgttgat
    18481 ctgctatcat agtgtgattc ccaggtccaa ctggcgcaga aggcttagct ggcgtaggtt
    18541 tcttaacagt tggcgttgga ttctgtgtct ttactacttc gccaacagct ggatatgctt
    18601 tcttgtcaaa tggtaatggg tgagtaagac tcttgtatat gatgtctgct cctgctgatt
    18661 tgttggcatc aatatctaca tgatacaaac gtccatcctc aaaacgaata agattccact
    18721 gatggtcatt tgttgtacta tgtacataat aacattcaat tcccatagca tcacataaag
    18781 ctttcaagct cctacacatt ccagaacaag cacctttttt agtaaccaat gtataagcag
    18841 tattggctcc ctctgctgcg ttccagttaa catatgttgt gttgttttta atgtgattat
    18901 aagcaaccct aatcttagca tctgtggtca tgttctttgt aattttcttg ttcataaagt
    18961 ctgctgttgc ttgtgctacc gaattaagtt gagcttgtga taactttgga ccatatatac
    19021 tgttggttcc agctacataa cttttcggtg tctttgcagt aacatcttta gctgtcatac
    19081 cataaactgt tacactcata catgaggtta aaaccatcat tgcaatcaat agtttagtag
    19141 ctaatttccg gatttttttc atattagcat tctcctttat aatatatttt actttcaatt
    19201 ccctaccatt aattaagttc attttagatt taaaatatgg attatcaaca tgtatgcata
    19261 gcaattcacg tggtcataga atatttagat ttcttggaaa atctgttcta tatttcctat
    19321 atagttcgta tacaatccaa ctcacaaacc tgcagttttg atatcatcac aataaaatga
    19381 taataattaa tatattcaaa aatgttggtc tgtaacaggt atgtcaattt tccaattatt
    19441 ggtaatggcg agagtgagga gaattgtcaa taatacattt aaaattaaaa ttgtatacac
    19501 ttcatacatt ctcccctaac aacattatac agattataat ttgtatattc aatacatttt
    19561 ttggaaagta taattatatc aaaatatgtg attatgtata gatacaatcc actatggaga
    19621 aatataaaag aaaagagtat aacaaacaat aaaaaataag atgattcaaa ttttattttg
    19681 aaacatctta tttactctac aaattaagat tatttggtga attatttaat tattattttt
    19741 tattaaagaa attttaaatc ttaatataaa atacgctatt atacataata atccaaatgc
    19801 aaatgctact ggaattaaca tctccgattc aaaataaaag aaatattcta agaaaatatc
    19861 tggatttact atattcccat tcttgtctaa aaaatctttt ccattatatc ctaaatgctg
    19921 tataaaatta cttatgttat tataatctgc ttccctctca tataccatat tagcattcaa
    19981 tccagaagaa cttaaattag tgtttccatc tttcatatct attacatata gtctaagagc
    20041 tttgacttta ctatacttat ctttatcaag tattttttca agttctaact tatattcacc
    20101 aatctttgtc atatcatgtc tttctgccaa ttgctttatt tctccatcaa gttcttttcc
    20161 taaattatac atattatgtt gtaaactatt attgtaatac cacataaatc cagaaattaa
    20221 aaatgcaatt atacttatgt aacctaatac ttttttaaac cccattacaa ttgatttatg
    20281 cctatccaat gataaagata gttcttttat tatattacat aattcatact gcatttcatc
    20341 accatcatca aatctttcaa ttgctttttt acatgcttct tcttcatcta atccttctaa
    20401 tttaaattca tttgcagatt ctataagatg gcatctcatt tcctgtttta attctatagt
    20461 acttttattg tcacattttt tatatagttt atctaaatat tcatctatta gtttcataaa
    20521 ttaatccacc tctcccaaaa attgattcat aaccttttta ataaatctcc attcttgttt
    20581 ctttatttct agaaaatctt taccttcatt agttaaatta taatattttc ttcttccacc
    20641 tgaactttgt tcattgctat aataagattt aattaaattt ttagattcca ttcttttaag
    20701 tgcaagatac attgttcctt cttttaattc aaactcactt ctttctctta cttgctttgc
    20761 aatttcatat ccataacaat ctttcttttc taatatagaa acaattaata tatcgatata
    20821 accttttaac acttctttat ttaactgcat tatgtaccac cgccttttca cctactactc
    20881 tataatgtat agtacttata tttactataa taatacatag tactctatat tgcaaggttt
    20941 atattctaca atagactcaa aaataataaa tagctgtata ttaatattta atctataaat
    21001 actaatatac agctatttat caaattttaa aaataaattt ttgttttatt aatgttgtca
    21061 taacaacatt tacttgattg aaatagtatt acctataagt ttaaatatat ataataatag
    21121 acttgattct atttcatatt attaaaatag agtaatagtt aaattctact actctatcta
    21181 taatctattt cctaattatt taatctcaaa tttagctctt catcatttaa atctttcata
    21241 agatttctac aggtactagg tttattccaa cagaaagact agggcattaa acacttatat
    21301 atctgtttct ttagactgta atattaatat tttttaaata cgttgacttt tgctttttct
    21361 aacttctctc catgatagtt ctcctctatc aagagctttt ataaatattt ctgctgaagc
    21421 tagatttgta gctattggaa catgataaac atcacaaagt cttattaacg cttgtatatc
    21481 tgtttcatga gcctgagatg tcaatgggtc tcttaaaaaa ataactaaat ctatttcttg
    21541 tgttactatt aaagaaccta tttgttggtc tccacctaaa ggaccagatg ctaatctatt
    21601 tatatttaat tcagtttcat ccattattct ttttcctgta gttccagttg catatagtcc
    21661 atactttttt aaaattgatt cataacctat acaaaatccg accatagtgt ttttcatttg
    21721 gtcatgtgct actaatgcta tattcatata tctaatctcc tcaatttatg tttagatgta
    21781 tttaaattta gaaatttatt ttctttcttc tcatacacac atttagtact aatcctaagt
    21841 ttgctaaaga tgtcaataac gaacttcctc cataacttac aaaaggtaat gttactccag
    21901 ttactggtat taacgcaacc gtcataccta tattttggat tatctggtaa ccaaacattc
    21961 ccataacacc aaccactatg agggttccat aaaaatcttt tgcatctctt gcaattgcta
    22021 aaagccttaa taggaatatc ataaataaga ttatcaacac tgccattcct attacaccaa
    22081 gttcttcacc tacaacagca aatataaaat cactatcttg tacaggtaaa aaatcttctt
    22141 gattttgact tccattgtaa agtcctttac cagttacacc accagaacca attgcaatca
    22201 gagattgcat aacttgatag tttcctttta gtgttacatc ttctggattt agaaaagctt
    22261 ctattcttac cttttgatgg tctgccatca ttaaatacat cagtggcatt gacactaata
    22321 gtatgattat tcctcttttt atcaactttg agctaagacc tgctgtgaac agcattgcaa
    22381 atatcataca acaaaataca attcctgttc ccaagtctgg ttgtgcaatc aataatccga
    22441 taaatggaag agaataaact acaacaggca taacttcctt taacgtattt aatttatcct
    22501 tcttggattc aagtatcttt gcataactta gtacaaatgt taatttgact atttcagatg
    22561 tctgcaagtc aagtggtcct aagttaatcc acgacctagc tccacctttt actgtcccaa
    22621 ttccaggtaa taaaactatg gctaacaaaa taagacttat tatataaagc gctttataat
    22681 acctgcctag aaggttatag tcaaaaaata atatgactat aatcattcct atcccaagta
    22741 caaaagctaa tccttgttta atcaattgat tatatgaacc tgttgaatta gcatgtgttg
    22801 cactactaag tataacaagt ccaaaaataa agatagctaa tactgtaact ataagtttcc
    22861 agtctaactg ttttatcaac ttaattgtcg acttataatt aatattgatt tttttcaaag
    22921 aatcaccgtc tttctatctt taaacatata attaaataaa aggggcatat accaataagg
    22981 atatccccct tttaagcact aattacatac atctatcttt tatattcttt agtggtatat
    23041 tagcaactaa tgcagataca ggtttgtcat catgctcacc tctgcattta gacattttta
    23101 tttcaagacc atcatcttct atttctgcat aattagctat tactttcaaa atgtctgttt
    23161 ttatcatctc taaaagttgt ggtgaacaat ctactctatc atgaactaaa actagcttta
    23221 acctctcttt agcaacagat ttactagttt tagcctcgtt agaaaaaact ctaaataaat
    23281 ctaacacaga tgtatcctcc tttgctactt agccatgcta aacatttttt taagtctacc
    23341 aaagaatcca tcttcaactt caagatcaag tagaggaact tcttcattta gtatcctttt
    23401 tgcgatattt ttgtatgctt gaccagcaag tgacttagaa tcaagtatag ctggctctcc
    23461 tttatttgtt gatataatta tgctttcatc atcaggaaca agacctaaca aatctattgc
    23521 taatatttct attatatctt gtttatccat catgtctcca cgcttaacca tatcatttct
    23581 aattctattt ataactaatc ttatctcttt tatttcattt gcttctaata gacctattat
    23641 tctatcagca tctcttactg ctgatatttc tggattagta actacaatag ctctatctgc
    23701 cccagctact gcatttttaa agccttgctc aatacctgct ggacaatcta ttattatata
    23761 ctcgaaagat tcttttagtt tctcacacag gtcaatcatc tgctcaactg agacagcatt
    23821 tttatctcta gtttgtgctg ctggtaataa atatagatta tcaaatcttt tgtcttttat
    23881 tagagcttgc ttaagcctac aagttccttc aactacatct actatgtcat aaactattcg
    23941 attttcaaga cccattacta catctaagtt tctaagtcca atatctgcat ccacaactac
    24001 tgttttttta ttttctaggc ttagcgcagt tcctaagttt gctgcggtag tagtttttcc
    24061 aaccccacct ttaccagatg ttataactat aacttcgctc ataatactac cccctatttt
    24121 tctttctatt tgtctaactt tgacaaatag ctttcgatta caattcttcc attacttaca
    24181 aaggctattt ctgggctaat ttctgattca ctttcataat tttcttcatc atctggagct
    24241 tctgcaatat tatctgctat ttgtaatatt ttaggattaa gatttccagc aacaacatat
    24301 gcaaattcat tgccttctgc acctgcatgt acaaaacctt ctattttacc cattacaaaa
    24361 acattacctc ctgctacaac cttagcacca gcatttatat ctcccataac aactgtattt
    24421 gattttgaaa ggacttttga accaggtttc atatcattca atataactac atcaccttca
    24481 aattcaatat tttcaccaga tcttagggta ttgacatatt ttgttggaaa attactattt
    24541 tcttcaattt tttgatcttc aacaaattcc acatcaaatc tagaagtaat tccttcttta
    24601 agttctagaa tctccatgtc agttaaacaa tcactattaa ttttactaat tttagcccca
    24661 ttaaaaaagc caacatatgc ttccaatttg tttattattt tttcctgtat ttcctcaaat
    24721 ggagcttctc tttttatatt tactattatc cctcttttat tacccttgaa ctctactagt
    24781 tcttgactac aaatttctct taaagacata acaacctcca gagtgatata tcatttatat
    24841 tcttcaaata cgctttaaac ccttttattt tttctatata aagctaaagt ttatacatag
    24901 attgagctat ctattaattt gtgactcgaa atttatattt tcgtcagaag aattgttaac
    24961 atcattcgtc ttgttgtcat ttttactatt agttggctct aatcccatat aagttccaat
    25021 aacttctcta gttggtaaaa gtgagaatac acttgaatca ccttgaggaa ttacacatac
    25081 aacagctatt tctgggtcat ctgctggagc aaaagcaaca gtccacgtaa aagaaccata
    25141 atcttgttta aatctatcta tttggtcatc tgttattttt ggatttaatt cttttatagc
    25201 ttttcttaga tatgaagaat tcaccttatc agtgtcctct aatctaactt ttactccatc
    25261 ttctaattct tcctctaatt tctttctttc ttcgtctttc aaatctttat tttctaattt
    25321 cttttttatt tccttttcct tagctaatga aagctctttt tctttttctg ctttcatctt
    25381 atcagctagt ttaatcgcat catttaggtt gacattataa gatgacatat gactttttaa
    25441 atattcatac tcgttatctg taggtatttt cccacttttc tcagctgtac cagtttttgc
    25501 tgctacatct attggaaaat cagcaaaagc actcttcgct gtaccttgtc ttgcaaccaa
    25561 tttcatacct tttgttaatt cttttaagtt atctggattt ttaaaaggta ttttttcgac
    25621 tttcttctgg tcattaattt taactgatga ataatcactt gaaacagctc tatcaactac
    25681 agataattct actaaattac ctccatttgc tatagcagct acatatcttg atatttgagc
    25741 tggtgtataa gcattttcac cttgacctat agctaagtta aatgtatctg cagtactcca
    25801 ttttgcaaag ttaaaataac taaatactgc taaatctgct acttcttcta ttctatcttc
    25861 tttaacattc attttcttta gcctattcat tgtttcgact ctaccaggag ttttcttttc
    25921 tgctgcccag cttacaatct cattgattct tttctcatat tctttaggat ttttttctct
    25981 agttatatca acaaaatcat ttgccatttc tctttctaaa tttgacttta gaagagcttg
    26041 tgttgatttc aatttatctt ctgtgctagg aactttacct gctctttctt ctacttcatc
    26101 ttgaagccct gtattttggt caagcccaaa taattttgca tactcaagta ttttatttgc
    26161 attcatatct ataccaatgc tttttccatc tggccatgtt ttacctgtac caattgttgc
    26221 catatatata ttacaagact cttgtattgc tttatataag tttgtcatac catggtttcc
    26281 tctaccatgg ttccatacat agtcaccaaa agatttttta cctaacatta taaccccagg
    26341 gtcatttata gtaaagtttg gatccagacc attttctaac gctgccattg aagttaccat
    26401 cttaaatgaa gaacctggct gaaattcccc ttgtgtaacc aagtttaaaa gtggacttcc
    26461 tgctagtaag tcatttggat tttttggttg aagtgcttta taatcctctg tagaaatacc
    26521 ttttgcaaat ttatttgggt cataattagg ataacttgat gaagctaata cttctccatt
    26581 tttaacatca atagctataa gagctgctga ctgtgctttt cctgcatatg cactaattgg
    26641 tttgtcccca aatttacttt taaaagtacc tcctttagaa gcaacttcga ttatctgttt
    26701 taatgcatta tctgaaactt cttgtaaatc tttatctagt gtaagataca cagtatctcc
    26761 tgatttaggt tttttagatt caatttcttt actaattcta cccaatgcat caactttaac
    26821 cattttataa ccatcagttc ctcttaatct actttcatta ctcttttcta ctcctgcaag
    26881 acctaccatg tctccagttt cataaccttt ttgaaggtat gattctattt gagtggatgg
    26941 catttttcct acatatccta acatatgaga agctaatgac ccattaggat aatatcttac
    27001 tggttctact gctattgaaa caccaacaag gtccatagca ctttcttcaa tttgagcaat
    27061 cgtagtttct cctacatcct tagcaatagt tactggatta tattgagaat atccttttga
    27121 ttttatcaaa tcccttacga ccattatttt tcttgcatct tcatcactca aacttttatc
    27181 aatttctaat gcatcactat ttcttacttt ttcaaacgct tctttggcac tcagtttagt
    27241 ttcttttatc ttataactag ccaaccaatc tctcttatct ctttctgctg tgaacatcca
    27301 tttactaact aaaataggtg gataatatcc attttcattt agttttgcct gtaatcttgt
    27361 cgcatccaat cttttatctt cttgagataa tattccagct gatataagtt tgtccaccaa
    27421 gtaataaaaa ctttccttag cattataatc atttggaata ccattttctg atttatattc
    27481 cctaatatct ctgtcatatg tataatagta ctttccattt tctacatata taggaaactc
    27541 atctacatat tcttcaccat ttctctccag caaatttata agttttaatg atatttcatt
    27601 tgctcttgaa tgcttatttg catctttctt attaatatcg ttacctgaaa cttgaacagt
    27661 aaataagttt ttatttcctg ccaacagtct tccatatcta tcttttattt ctcctcttgg
    27721 agcttctatt gccaactttt tatatgtttt attctcagct aactcattgt aatattcata
    27781 tttaaatgta gtcatataga ttatttttac taaaatagct aaaaatatca cgcccatgac
    27841 tatcttaatt atttttagtc tatcaacttg tttattttct tccatgaaat caccaactaa
    27901 tcttctttaa gttttaaaac tgctctttta gataagcgat atattactaa accaattaaa
    27961 ctattcacta ttggtgctac tagtagacct tttacaaaaa gtgttgatat gttgtagctt
    28021 tgataaatta tactagatgt acctatattg acaattgaat caattaaact gcctataaaa
    28081 attaaaacga aagtaataat ataactacct ttatatagct gatctctcat gtatccaatt
    28141 gcatatgcaa taataaacaa aattaatgca tttacaccaa aaattccacc aacggttatg
    28201 tctttaataa gccctattat tgctgctata atcccacctt ctaattcatc taaataaaga
    28261 gagattatgg ttacatatat aagaactaaa ttaaagctta tgccaaaaat atctatataa
    28321 tttgttatac tattttctat agtcataagc acaatcccca acagacaaag taaaactttt
    28381 ttcattgttt ttatcccctt tatcctatat ttcttggttc tatgactaca acgtcattta
    28441 tattcttaaa atcaacataa ggttttacaa ctacatattt taatgactta tctttatcat
    28501 caaccacttt ttcaacttcg ccaattggta taccatctgg gaagaatcca agacctgatg
    28561 ttgttattat atctccttga attacattat atgatgagtc aaacatatat ccttgcaaat
    28621 atcctttact attataacta tctttattat ctaaagtagt attttgagta attgtacctt
    28681 tagcattggc atcctttgct agtttaaagc ttacagatgc cttagaatcc aatagtgaaa
    28741 ttgccttact ataattgttg gaaacctcat aaactatgcc aactaatcca ctaccattca
    28801 taactatact ttcttttttt acacctgaat tttttcctgc acctatgaca aaactctcat
    28861 accagtttcc atcattttta ccaacaacac ttgctgaaat acttgtcgcc ttatactctt
    28921 cttgtacaaa gttcagtgtc ttttttaact cttctagcga ttctgtttta tctagtttgg
    28981 catttaaagc tatcatattt tttttaagtt tttcattttc ttcttctaat ttttttacct
    29041 ttttagaatt atctttaaaa tttgctacat ctttaaaacc atttttgata aaagaaaatc
    29101 catcatttat tcccttacct acacttgtaa tagcatctga agctactcct aaatttactg
    29161 gactaccact agaaaattta ccaattgata tacccacaat tccaattaaa gtgatagcaa
    29221 ctacgcccgt tgctatcact ttaacattaa tccttttttt ctcatttttg ttcttgtcaa
    29281 atctcaaggc catcaccaac ttctaattct tagtattcat cattaatact ttttcaaaga
    29341 tttcttggtc ttcaacagat ttacctgttc caagtgcaac acaatcaaga ggtgtttctg
    29401 ctatttgtac agacatacca gtttcctgtg taataagctt atcaagacct ctaagcaaag
    29461 cgcctcctcc tgttagcatt attccgtttt ccattatatc tgaggctaat tctggtggag
    29521 ttctttctag tgtagatttt attgcatcta ctattgaact tacaggttct tttaatgctt
    29581 ctctaacttc tgtagagcat atttctattg ttttaggtaa tcctgagatt aaatctctac
    29641 ctcttatttg catatttatt tcttcatcat ctttaaatgt agaacctatg ttaattttta
    29701 cattttcagc agttctttca cctatcataa gattatattc tttttttaca taagccacta
    29761 tagactcgtc aaattcgtct ccacctattc ttatagattt agcagtaacg attcctccta
    29821 aagatattac agctatttct gaagtacctc caccaatatc aactaccata ttaccttctg
    29881 gttcttcaac ttttaatcca gcccctatag ccgctgccat tggctcttct ataaggaatg
    29941 catctttagc tcctgcttgt cttgcagcct cttctatagc tctcttttct acttctgtaa
    30001 ctccaaaagg aacacatata gctattcttg gacttacaac acctttttta tcagccgctt
    30061 tttgtataaa atagctaatc attgattgag ttatgtcaaa atcagctatt actccatctt
    30121 tcataggtct tatagctact atatttcctg gtgttctacc tatcattttt ttggcttctt
    30181 cacctactgc taatacctct ttactatcat ctcttattgc gacaactgat ggttctctaa
    30241 caacaatacc ttgtcctttt atgtaaacta atgtatttgc agtccctaaa tctattccca
    30301 tatcctttgt catcttatta aaactaaaaa aacctttttt ttctttcttt ttttccttag
    30361 ccatgatttt actccttcct actattaaga atcatgttta aaacattctc ctattatttt
    30421 atcacatata aagtcaaatt atcatatttt ctttaaagct aaagtataat ccatctccaa
    30481 taattatatg gtctattatt tctattccaa ttatttctcc acatttaata agtcttgatg
    30541 tgatattttt atcttctctt gatggttcta cacttcctga agggtgatta tgcatcacta
    30601 ttatcttact tgcacttctt cttatagctt ctttaaaaac ctctcttgga tggactaatg
    30661 acgagcttaa agtccctata gatacatcta catcagatat tatctcattt tttgtgttta
    30721 aaagaaccgc tttaaaaacc tcttttttta aataccttag gctatccata taatacctct
    30781 gtatatccca aggattcatt attttatact ttataggttt aaaactagct actctagagc
    30841 ctagttctaa agctgcttta atttgggttg attttgataa cccaattcca tctatattac
    30901 acagctcctc tattgtcata tcttctaaat gtctaatacc ctgaatatct ctatttatta
    30961 tatagttggc taattcaata gcatttttat tcttgttgcc agttcttaaa agtatagcca
    31021 acaactcagc atttgataag ctttttacgc ctttggcaag catcttttct ctgggtcttt
    31081 cctctggtgc catctctttt accttaatgg ttgaattaaa tgactttttc agataaatca
    31141 cactccataa aaaagattta tactaaaata tttttttaat aggtcgccta accttgaaat
    31201 tggaagacca actatattaa aataatctcc tctaatttct tcaactaaca aagctccata
    31261 accttgtata ccataggctc ctgctttgtc aaatgactca ttagttttca gataatcctc
    31321 aatatcctgc tctgataacg ttttaaattt cacattgctg attacatagt caattacctt
    31381 tttatcttcg cacaagttta ttaagctaat acctgttatg acttgatgct ctcttccaga
    31441 tagtcttttt aacatatctc ttgcacaaga ctcatctttt ggttttccta aaatagcatt
    31501 gtctaaaaca acaactgtat cagctccaat aacaacatct tcattatgtt cagatgctac
    31561 agacatactt ttttcaaaag ctaatctcat aactaaatgt tttggtgttt caccttccaa
    31621 tataatctca tcaatttcat ttttaattat atcaaatctt acattcgtat tctctagaat
    31681 ttctttcctt cttggagagg ctgatgccaa gattatattc atttattcac ctcatttgta
    31741 cgtaatttgt acctatttag tctatcacta tattgtaaaa aattcaacag aaatgtcgaa
    31801 ccttttttgt tacactattg ttatatttat taccattaga ataaatatac ataaaataga
    31861 ggtatggaaa ttattccata cctctgtttt atgtactcat tagagatatg gaaattattc
    31921 catatcctta ttttgtccat attacaaaat tttaatagct ttctttggac atttttccat
    31981 acataaatgg catcctacac atttatctgc atctacctta tgtttttctt ttaattctcc
    32041 ctctattgca tcaaacttac attgtttttt gcacactgta catccaacac aaagttcttg
    32101 gtcaatagta actttctttt tcttagttat gtcacctgat attacttttg tagggcattt
    32161 tgctacacat tgcatacaac ctacacactt attagggtct atcttagcta ttttgtcttc
    32221 aaatattatt gcatcaaatt tacaagcttt tacacacatt ccacagccaa tacatccagc
    32281 agtacatttt tccttaacag ctttaccaaa ctctttgcta ttacactcta caactacttc
    32341 ttgactttct ggttttgtga ttattatacc cttaggacaa acttctttac attttccaca
    32401 atttacacac ttttcttcat ctattactgc tattccatca actatagaaa tagcatcaaa
    32461 tttacaagca tctttacatg ttccaagacc taaacatcca aatttacaca tcttagcacc
    32521 tgagtttaaa acatttgctg ctctacaatc tgatattcct tcatactcat atttatcttt
    32581 tgcacttgaa caagttcctt tacaaataac ttttgctact tgtttctcac ctgcttcagc
    32641 acttattccc attatttctc caacttttgc accaacatct gctccaccta cagggcaacc
    32701 attaactggt gcattgcctc caactatcgc atttgcaaga cctccacaac ctggaaatcc
    32761 acaacctcca cagttggctc ctggaagtac tcctagtata gcttccactc tctcgtctac
    32821 ttctacagca aactttttag atgcaaaatc tagtactatc ccgaagatta agcccataat
    32881 tcctaaaact aatacagctg taagtatcac cattttcacc cctctttttt atagctttat
    32941 aagtcctgta aatcctaaga aagctattga cattaaacct gctgatataa gcgttatagg
    33001 gaaaccttta aatgcttctg gtatatcagc taattctagt ctttctctta tacctgcgaa
    33061 tattactatt gctaaagtaa atccagctcc ggctccaaat ccgtttatta ttgtttctac
    33121 taaattataa cttttttgaa cattaactag agctatacca agaactgcac agtttgtagt
    33181 tataagaggt aaataaactc ctaatgcttg atataaagat ggactcatct tttgaattac
    33241 catttcaacg aactgaacta tagaagctat aaccaatata aaagctattg tttgtaagaa
    33301 tccagttcca gtttttacta ataaaatctg tataaaataa gttataattg aagctagagt
    33361 taaaacgaac gtaactgcaa ctcccatccc tactgctgta tcaaccttct tagaaactcc
    33421 caagaaagga catataccca agaattgaga tgttataacg ttattaacaa gaacgatact
    33481 taaaaataaa agtattaaat tcatttatta cacctccact atgctttttt acttcttaat
    33541 ttattaaatc ctgcaaataa gaatcctaat gttaagaatg cacctggtgg taatataaat
    33601 attaatactg gttggaaaga tgctccaaat aatgtcattc caaataaact accatttcca
    33661 agtaattctc ttactgcacc tattattgta agtgcaacag taaatccaag accttgacct
    33721 acaccatcaa ctattgaagg catagctcct gttttgaaag caaaactttc tgcacgagct
    33781 aatattaaac agttaacaac tattaatggt atatatatac caagagcctt atcaagagca
    33841 ggaacatatg cttttaaaag catacctact attgtaacaa atgtagctat aactactata
    33901 aatataggta ttcttatctt atctggtgta atttttctta ttaaagatat aactaaattt
    33961 gcacatatta aaactgctgc tgttgaaaga cccataccaa ttccatttat tgctgaagtt
    34021 gtaacggcta gtgttggaca catacctata acttgaacaa atgttgggtt ctcatctatt
    34081 agcccatttt taaatacttt agctaaattc ataattaacc ctccttattt attaagagca
    34141 ctattgaaaa catctatagc agcatttact cctgtagtaa ctgctgtaga tgtaatagtt
    34201 gcacctgata ttgctaatat ttgattatct gctgttgtac ttccttttgc tacttcaaga
    34261 ggctcagcag tttttccttt gtattgaccc ttaaatgcat catccttagc ttttgctcca
    34321 agacctgctg tttctgacat attaccaatg tcaacacctg taacttgacc ttcagatgat
    34381 atacctacca taacttcaat ttctccacca tatccacttg gtttagcttt taaagtatat
    34441 ccaaccactt cagaaccatc taaaccttca tacacttcag ctataagacc atctccaagg
    34501 cctttgtaag tatcttcctt catttcttta aattcttttg cttctggaag gactgctttt
    34561 ctaagttcat tatttgcttg tatatttctt tgttctatta ctggagctgt aacctgatta
    34621 gtagctccaa gagctaatgc agctattgca cttatagcaa gtaaagtacc acctaatctc
    34681 accatactgt tcattattta gccacctccc caaatactct atttctaaca aacttatcta
    34741 taagtggagc aagacagttc actaatagta ttgagtaaga tacaccttct ggatatccac
    34801 catacattct tataacagtt gttataagac cagctaatac agcgtatatt atttgacctt
    34861 ttttagtcat aggcgaagtt gtataatccg taagcatgaa gaatccacct aacataagtc
    34921 ctccagcaaa cagttgatat attgcgaaag ttatattaaa tccacctaaa aggaatgtta
    34981 atataaatac agttgctatg taaaatactg gtataacata atttattatg cctttataca
    35041 ttaggtatac tccacctaat aataataata ttgctgatgt ctcacctata catccaccaa
    35101 tattccctat catcatgtca gcaagactaa ttccattgct agaaaggtct gccagtcctg
    35161 ctgctccatt tttcaaaaag cttaatggag ttgctgtagt aactgcatct aaatttttac
    35221 ctatccagtt aacacctggt tgagtccaag cagtcattgc tactgggaat gatgctaata
    35281 aaaatgctct tgcagcaagt gctggattga caaagttaca tccaattcca ccaaatacca
    35341 ttttaactac taatattgca aatattcctc ctactagaca catccaccaa ggaagtgatg
    35401 ctggtacgtt aaatgctaat aataatcctg ttacaacagc tgaaaaatct cctatagtac
    35461 ttttttgctt cgtaaatttt tgatataaaa attcagtacc tactgtacca agtatacaaa
    35521 aaaacatagc actcaaagca ttaagtctaa agaagtatac tcctgctact gctgctggaa
    35581 ggagtgctat aataacttgt ttcattatat atgaagtatc ttcattactt ctcacatgag
    35641 gagaagatga tactatcaac ttattttcca tcgtttttcc cccttaactt tctttatttc
    35701 tgagcagctt gctttcttct ctttgctcct atttctctct ttgctgatct tatagattga
    35761 agtaatggtc ttcttgctgg acaaataaat gagcaagacc cacattctat acaatccatt
    35821 gctctatgat attcagctgt gtcatagtca tcttttaaag aatatgcact tatgaaaagt
    35881 ggttgtaaga atgatggaca tacatctgta catcttccac atcttaaaca gttttgaata
    35941 tctggagtac gtgattcttc ctcatccaaa cataaaattc ctgaagaacc tttgttagta
    36001 gctatttcag tagtatattg agctattccc atcataggtc cacccattat aaccttacca
    36061 atcttcttat cttctttaaa tccaccacat tgttctatta tttctgaaac taatgttcca
    36121 acttttgtta ttaggttctt tggctctttg atgcaactac ctgttattgt agtgattctt
    36181 tcaaccaaag gcatacctgt tttaatagac ttagctatct gtgctgctgt ggcaacgttg
    36241 tcaacaactg cacctgctgc tattggtaat ccaccagatg gaacttcttt gcctgtacac
    36301 gcataaataa gttgtttctc tgctccttgt ggatatttca cttgaaggcc aacaacttcg
    36361 atttcgctat agtctttagc tacattttga attgcttcta tagcatctgg tttattcgtt
    36421 tcaattccta taaatccttt tttgacatct aataccttca ttaatgctct taaaccaaac
    36481 acaacatctt ctggattttc aaccattaat ctgtggtctg cagttaagta tggttcacat
    36541 tctgcaccat ttaatataac tacttctgcc ttgctatctg gtggaggaga tacttttaca
    36601 tggttaggga atgtagctcc acccatacct actattcctg cctcttttat gatacctact
    36661 atatcttctt tgctcaaatc ctctaactga ccttttggtt gaacactctc atgtaattct
    36721 tccttaaagt cattttcgat aactacacat tgagctgaac ctcctggtac ttcatgttgt
    36781 tcaatagcaa taactttacc tgatactgaa gaatgaacgt tacatgaaac aaaaccttgt
    36841 tgttcaccta ttttttgccc aaactttact tcatcaccaa cttcaacaat aggtttagct
    36901 ggcgccccta tatgttgctg aagaggaatg taaactatct ttggagcttg agctttttca
    36961 agtgcctttg tgttagagta ctcttttcta tatggaggat gtatccctcc cttaaaagtt
    37021 aagagtttca ttgttttacc cccttatcta taaaaaaaca ttttttctgc cttctataag
    37081 tatactatat atattaaaaa atcttaacaa ttgttaaaaa aatatccgta tttttataat
    37141 ttattttata aatcaatacc tctatattaa gtcaaactga ggaaaaggat tgcttaatta
    37201 aacaatcctt ttcatatagc tttctaaagt ccaaattttc tgtattttat tttatagaat
    37261 ttataaacat agagtactcc tgcatggatg ataaaagcag acttttactt acactatatt
    37321 tttcttcatt tgctgctttt gaagctgtat caattttttc attcacattc tttacatact
    37381 ctattaaatt atctttaaat aaacgcattt cagaatagtc aatcttttca gcttcttttg
    37441 atatattttg tgatattgcc tttctatttg tcaaaatagt attatatttt tccatatcta
    37501 cattattttc agcattcgac caaaaacttg attcttcttt aaagtttgtt attaatttat
    37561 ttaattcttt agatatactc tctatataag cgtagttact tgtatactct aaagacaaca
    37621 taggtgcatc taagtgtgat aaaaatgcat ctggaaacac ctttcttaca ctgcttatct
    37681 gctttctaac atcattttca tcaaaagagg aataggtttg tatttttttt actccatcct
    37741 tctccataac tgaaaaaggt atgtcattat taactaatga tgtctgtatt tttttcaaat
    37801 catcattatt atctattgca gcaacttgaa tagtatacat atcccagcct tctatagtag
    37861 ctaatttgac ttcttctggc tctttagtgt tatttaccgc tttttctgga ttagtttctt
    37921 gtttatcatc tgaattggtt tgtgatttag attttttccc tttttttatt gaatttaatt
    37981 catcagatat atctttataa gttatatctg atgaattatt tagaaatggt attttagccg
    38041 atacatactc caatatctta ctatctttta tttttgtata agaataatag ccaattagac
    38101 acaagcaagc aatcgttata acatatttac gtaaatcaat cttatgtcta ttattattaa
    38161 atcctctgta tatcgttttt cttctattca ttagtttgtc cctcccaaaa ttatattatt
    38221 aataaagtat atttttaaga gtcacaattt atgaatataa ataattattt cttctaattt
    38281 tttaataaga aattgtactt actaaacaaa tcttcttgca ccaagtaata ctttagacca
    38341 atatgaacta gttaaattat ccactttaac cttattagga ttagtctgag taccactaca
    38401 atggataaat ttactatttc ctacatatat acctacatga ttagttgttc catcaccatc
    38461 agtgtcaaaa taaactaaat ctcctggtgc ataatttccc atagaaattg cacttccaaa
    38521 attagcctgt tctctagaaa ctctaggaat agaaacgcct acagaatgtt taaaaacata
    38581 ctgtgtaaat ccagaacagt caaatttatc aggccctgaa gctccccatt gatatggtat
    38641 tccaataaga gtatatgcaa aatctacgat tgttgaacct tttgctgtag atttatctga
    38701 atttccagta aatgatggct ttgagttact attagattga gaattttggt tagatgatga
    38761 atttggtttt tcttttgtat cctcattagt ctcagaaata taactggcac tcacccatcc
    38821 aattgttcca ctcgataact ttaccttata ccaaccatta cttttagctt ttaattcaac
    38881 aacatctcca ccatttaatt ttcctattat agaatagctt gtcccaggac cacttcttac
    38941 atttaaactc acagcagatg ttaccttacc attcttgcct tcaattgatt cttcgctaga
    39001 tggtttttta tcagaattat tagtactatt tgaattacta gaattattcg ttccaacatc
    39061 ctctgatgtt ttagagatat attggctact agcccatcca gtaactccat ttgatagttt
    39121 tattttatac catccattgc tttgttctag taactttact acatctccat tatttgcttt
    39181 accaactaat gaatagttag tacctgcacc acttcttaca ttcagtctag aactcacatt
    39241 tactttacca tttccactaa tagttgtccc acttgaagtt ggattatttt gacttgatgt
    39301 accttcagac gaaccacttg ttgatatgta ttttgcactt ccccatccaa caacagaact
    39361 cgataccctt actttatacc atccattaga cttttctaaa atctctacag tttttccctt
    39421 gtataatttt gctaccttat cgcaatcaga acttggtcca cttcttatat tcaaggcact
    39481 tgctgttact gttccctttt caagagcact tgcatttatg gagctaacag atactgctac
    39541 tgccccaatt cctaaagctg ctatagcttt tttcactact atcactcccc ccaacaaatt
    39601 tttatagtca taaattcata acattattat ccatttttag tccctacaat ttaatgataa
    39661 cttattttct tattaattgt aaagaaatta taaacatatc cttaaaatta gtgattttta
    39721 ggaagtattt caatccaata attatctggg tccgctataa aataaattcc catactttca
    39781 ttttcaaaac atatgcaatc taaatcttta tgaagttttt ttgcctcatc aaactcctca
    39841 acttctaaag ccagatgaaa ttcattgtct cctaaattat atggtctatc ccaatctcta
    39901 agccaagtta attctaatgt atgactagta atgccatctc ctaaataaac taatataaaa
    39961 cttccatctt ctgcttcctt gcgctttacc tctttaagcc ctaaagcttt tttataaaaa
    40021 tctaaacttt tttctaaatt agtaacattg aaattgttat gacaaaaatt aaacttcatt
    40081 ttgaaatcac tctccaattt ttattttttt tatattatat cattattata aatttattta
    40141 aatcatatta agttaaaaat ttgaatgatg atgaccagtt accaaatcat ggtaaattat
    40201 ttaaaagaat atgtcaaaaa aagaataagc tctttcaaat gcataaaaaa tttataccca
    40261 agttatactt aatcatgcaa attggcagaa cttattcttt aaaactctaa cttttaagtt
    40321 tttctttaat aatataattt attacttttt ttctaatatc ttcagcatta taatcatctt
    40381 ctacttctat atccaaaagt tttgctattg acctcatatc ttctctagtc tttgacctat
    40441 agcttgatat taattcatct tttattttct ctggttctaa aagatattct tcatctcctc
    40501 ttttgaaaac aacgtatttt tgagcatatg aacttctatt gtagtatata tatcttgata
    40561 tttttcttaa aatttgatta tatgaaagtc gcttgttaat atcaagtttt aagtactctg
    40621 aaaaagcaaa tagctctttt tttgatttaa ataatgcttc tttctttata gtccttgata
    40681 ttgaagttac actttcttga tatgcacact tttttaacat ttttaaatat actctattaa
    40741 gaccaatact ttgattgaat ttttttatat tattattaat aatcttatcc aagttacctt
    40801 caaagtattt ttttgctcct ttttgtgata cataactctc aagttctttg tgggccatat
    40861 caagtatcat tttttttaaa tcctctttat atcccctaga ttccatgata ctccctccct
    40921 tagctattta tagtatattc aaaaagctca agaaatgtga gtcattacaa aattttttta
    40981 ctttttatgt atatattaat ttaaaagggg agataatagt aatgtaaaat caaacatact
    41041 caatctcccc catttttaga cctctattac tcccccaata gaggtctttt tttagtttat
    41101 caatttctat tcaattccct ttagttcaaa tcctaattct gctatcactt cttttaattt
    41161 ttcaatagat acatcatctt tcatatctac agatgcacac ttattttcta aatctacatc
    41221 taaaacttca ataccatcta tatcttctgt taatgcagtt ttaagatggt ttacacaatg
    41281 accacaactc ataccttcta ctaatagttt cttcttcatt taattacctc cttataccct
    41341 ataagggtat tctatcatat agtttatact ttttaaatag aaattaatca tttaatttga
    41401 ttcattcgat tttatatcta aattagatat tccctcatat acatcaaaat catttggagt
    41461 aattttacct tttaatctac tattacttac aatatagttg tttctcacag ctaaacttat
    41521 aaatgttgca ttatctttta tatatgtctg tacatctttg tatgcttttt ttgtttcaat
    41581 ttcagacgta gaacttgtaa gtgcagacat atatccattt aacttatcat cagtatatcc
    41641 actactcgct ataatactac ttgcatctgg tataattgat agtttccatc caactaatgc
    41701 taaatcataa tttttagaat taagagcatt ttccatatcc ttatctgaca gctgatttac
    41761 tgtactattt attcctatag cttttaagtt ttcatttatt atgtttgcag tttttattct
    41821 ctcactatta tctctgttta ctattatctt taagttcatt tcagaaagac ttttctttac
    41881 ttcctctttt tctctatttt ttttctcttc agcttctttt ttgattctat cttcttctgc
    41941 ttttttagct tttgcttctt cttctggcgt aagcttcttt gagttctttt tagctgattt
    42001 tttctgattt tttactttat tgtcattttg atttactgag tttacatttg catattctac
    42061 cttagcaaga cactctatcg ccttatcttt attaaactct aaatccttca tttcactatt
    42121 atagtatttt gattttgaat taagtggaaa attaactgga gtagcatcat ccatataacc
    42181 ttcactaata attctatctt tatctataga gtgtgcaatt gcttttctaa aattaacatc
    42241 tttgaaaaaa ggattattat aattaaataa tacacactca taatctcttc cttgatattt
    42301 tgttatatta aactcttttt cttgaaactt acttaaatca tttaatgtaa cattggttat
    42361 atcactatca agagccataa ccatagatgt ccttgcatct tcattaggca ccatacctac
    42421 ttttatgttc ttcatggttt ttggaacttc ttcatagtaa tctttgttta cagataaaac
    42481 cattccttct ctttctgtat atgattctat tttatatttc ccatttccta tcatattatt
    42541 attcttgtca tttacatctt ttgaatctaa atgattttga gatacaattg gaaaaattaa
    42601 actatcaatt gaaaaagcat atctagcttt aaattttatt gtaaaatctt tatctgattt
    42661 aatattcaca gaagctatat ttttagtaaa ttcattatat ggactatctg cacttttttg
    42721 aattaaacca atagtatagt ttacatcatt tgaagtaaca ttttttccat catgccactt
    42781 tgcatctttt agctttatat ctatactcat tccatcctga gctatattat actccttaac
    42841 taattgagga attacattgt agttctcatc tatagtaaat aaactatcat aaactaaatt
    42901 cattatataa ccaacagact tatcagtatt agttatagga tttatagttt ttggagttac
    42961 cattgttaag tttatatact tagcatctat agaactttga ctttgtaaac ttgaatcact
    43021 actactttgt tttgttttag tattactaca accagctacc ataagagtta tagctaaaac
    43081 gactgttaag acttttattc tcttcattag ttttttcctt tcttgccata tatcttatta
    43141 taatgttcgt aattattttt tactttttct acatattttg aagtttgctt aaaaggtata
    43201 tcatgtagat tttcgccatc tttactatat tcattatttt ctaaccattt tttcacatta
    43261 cctgaaccac cattatatgc agctatcact aaatctaatt taccaaattc tttgtataac
    43321 ttacttaaat accaacagcc aagtcttata ttagtctctg ggtcgaaaat atccacattt
    43381 tttaaattta gttcctctgc tccccaatct ctagttatgt ctaatatttg cattaatcct
    43441 tttgcttcct tttttgaaac agcagaacta ttaaacttac tttcggcttt aataacactg
    43501 taaactatat tttcatctaa attaaattct ttcgaatact tttctacata ctctgaatat
    43561 tttttaggat ataaaaattt atgtattact ttgctttcca ttaatagtgc cccaaataag
    43621 attataaaaa tagatagaat caatactttc ttactattca cgccaattct ccttcatgta
    43681 ctcaataaat ttatgtgctt tactttctaa ttcagttatt gttcccgaat tatctattat
    43741 ataatcacca tatttggatt tctcttcctg actcatctgt gaatttatcc tactaagtgc
    43801 ttcctgctca ctgcaattat ctctcttttg tattctacta atttgtactt cttgtttaca
    43861 agtaactact aatagcttgt caaccatatc taaaaaacca ctttctacca atattgccgc
    43921 atctaacact actatatttt cgcctttttt tctcaatttt tctatttcac ttattatttt
    43981 ttctcttatt cgtggatgag tcaagttatt taattcctta agtttttctt catcactaaa
    44041 aactattttc ccaagagctt ttctatttag agttccatca tcatttttta tactttgccc
    44101 aaaatggaca aatacttttt ccaataacaa cttatcctca aatatcttcc tggatataat
    44161 atcagcatcc actataggaa tgttaagatt tctaaatata tttgataggc tgctttttcc
    44221 acagcctatt cctcctgtaa gtcctaatat caacataaaa tcacctactt tgtctcatac
    44281 caagaactac ctacatttaa atctacatct aagtgaacat ccatatttac agcattttcc
    44341 atttcttctt ttactatttt cttaactata tctatttcat catcaattgc ttcaactatc
    44401 aactcgtcgt gaacttgtag tataagtttt gatttcaaat tgttctcttc caatttttta
    44461 tgaacattta tcatagcaat ttttattata tctgctgcac ttccttgtat tggtgcattc
    44521 attgcaaatc tctttcctct atttctttcc ataaaattgc ttgactttat ttctggtata
    44581 tatcttcttc tgtttaaaat tgttacagca tatccatcct cactagcctt ttctactgtt
    44641 gtgtccataa actcttttat tttatggtat ttagcaaaat aactttcgat atattctttc
    44701 gcctttggaa caggtatatt taaatcatca gctagaccaa agtcactttt accatatata
    44761 ataccaaagt ttacagcttt agctgcacct ctcaattcac tagtaacatc ttccatagga
    44821 acattaaaaa cttgtgaagc tgttttggta tgaatatctt catgatgttt aaatgcttct
    44881 atcatatttt catcctggct catatgtgca agaactctta gctctacttg tgagtaatcg
    44941 gcatcaacca acttacagtt atcatctgca ataaacactt ttcttatttt tctacccatt
    45001 tccattttta taggtatatt ttgaagattt ggttctgtag atgaaattct tcctgtagtc
    45061 gttatagttt gattaaatga tgaatgtatt ctattacttt ctggatttat tatatttaaa
    45121 agtccttcaa cgtaagtaga atttaacttt actatttgtc tatactcagt tatcttatct
    45181 attattggat gcttatctct taatttttct aaaacatctg cattagttga atatccagtt
    45241 ttagtttttt taattattgg aagctctaat ttttcaaata atataacacc caattgtttt
    45301 ggtgaattta tattgaatgg ctctcctgat aattcataaa tttccttttc taatgtagct
    45361 attatttctt taaattcaac actcaattca tccaatatac ttttgtctac ttttatacct
    45421 tcatactcca tatgacctaa gacttctact aaaggcatct ctacatgata aaaaagacca
    45481 tccatactca tatccattag acttctttcc atcataggaa ctgtttcttt aactgtgcat
    45541 attatttgac ccatatactc tgctaaatcc tcaaattcta aatcctcata gtttttagat
    45601 ttaacaccct ttcctaataa ttcttctttt gatttaacct tttttgataa atacttcata
    45661 gctattgcac tacaatcata tgaggtagat gaagttgaat ctattaagta ctcagctatt
    45721 gttatatcaa aatacatatt ttctaagttt atattatatg gttttaaaga tatataatca
    45781 tcttttaaat tatatccata ctttttaatt tcattatttg aaaatatact atctaacttt
    45841 gacacttcat ttgaatctac ataatatatt ttttctccat ctacacttat aaaaatatat
    45901 attatatttt tttcaagtat attaccttgt cctctaacag tttttaaaat aacttgtcct
    45961 tttttgttta cttcatctat aaatttttct atatctttta attttaatat ttctattttt
    46021 tcttctacgt gttctgtgtc atctgaatcg accaaatcaa ctaatcttga taagagactt
    46081 gtaaatccaa agtatctaaa tttatctaaa agttcatctt tatcataatc gccaaaaatc
    46141 atactatcta aatccacttc tattggcaca tctcttataa ttgttgcaag tcttttactt
    46201 tgaatagcta tttctttgtt ttcctctatt ttctttttta cactaccttt aagcttatct
    46261 gtattctcta ttagattctc tatactagaa aactctttta taagctttat acctgttttt
    46321 tcacctattc caggtactcc aggtatatta tcagacttgt ctcccataag accctttaaa
    46381 tcgataaatt gtgttggagt catctcatat ttttcaatta cagaattaaa gttgtattct
    46441 tctacttctc caaccccttt tttcgttata agggtagttg tattatctga agcaagttga
    46501 atagcatctt tatctccagt tactatgtat accttatatc cattttcttc tgctttttta
    46561 gaaacagtac ctataatatc atctgcctca taaccatcta tttccaatct atttattttg
    46621 aatttatcta aaaggtcttt taatggctgt aattgttctg ccaattcgtc tggcataccc
    46681 tttcttccag ccttataatc tttatattct aaatgcctaa atgtaggtgc ttttctgtca
    46741 aaagctacac ttatatgtgt tggtttatat atatctatca ttttaaataa cattgtagta
    46801 aatccatata ttgcattggt ctttaaccct tctttattat tcatttctgg cagagcataa
    46861 aaggctctat ttattattga atttccatct attataatta attttttttc caaattatat
    46921 cactcctaaa aattatctat ttttgtaaca tatatattat ataccaatat actgttattt
    46981 aatattccca taataataat agtatattaa aattaaatat gttgcaaaca atatattttt
    47041 ttgctataat aatatacatg acatgcccga gtggtggaat tggtagacgc agtggactca
    47101 aaatccaccg gactaatact ccgtgccggt tcgagtccgg cctcgggcac cattaaaaac
    47161 tcctaaagct atttattcaa tagattagga gtttttttat ttttgattta aattttaagt
    47221 tattttttga aattactgtg tctttttaaa atttatataa ttatataaat ttatcttcta
    47281 gcattaattt aaaaactaat ttacttttat ataattttct attttatatc ataacttatt
    47341 acaacctttt atctaattta ttgtatacaa caacactaca aataaattga aataaaataa
    47401 gcaatccaag aacaactaaa acccacttgc ttattaccat tacagaaaat acactcaata
    47461 tagaaacaat aaatataaga attacaagaa catagcacat gatttgatta gtaatacgtc
    47521 cagctttatc acgtaacata attcttcttt catcattcat ctctatcctt tgatttttta
    47581 tcttttcttc ataatctact gctctttcag gtttactcca atacatatat tgaagaatca
    47641 tacatacacc tggacctaaa gcagctccag ataatcccca aataaaagcc tcaaatgaaa
    47701 actcagtaaa tgtagccaat aaaacaagta aaattccaca aataaaatat ataattccaa
    47761 catataacat attctttttc atttttactc ctcctcataa ataaatattt cttcaatact
    47821 catatcaaag tatctagcta tcttaaaggc taagatgata gaaggattat acctaccatt
    47881 ttctaatgaa cctatagttt gtcttgatac ttgcaaaata gaagcaagtt cttcttgttt
    47941 tatgcctctt tcttttctta tttcttctaa tctatttttc acatctatcc ccctttaata
    48001 tctcaactac ggaaagtcta ctttccataa ttatacaact atattccatt tatgtaaagc
    48061 ttactttcca tatttacaaa aaaataacag actattttca gcctgtaatt ttagaatttc
    48121 atattgttta ttaattttaa tgttatttat taattccata ttatttatta attttaactt
    48181 ggtttctgaa ttggaatcca aacttctgta gtataatcag gagcattgat atcgccattg
    48241 ggataaagtt caatatctgg taaattagca tacacatacc cagaacttgg taaccactca
    48301 gtaataattc ttttttgcaa ttcctgtatt gccagagcat ttggcattgg agaaacacat
    48361 tcaaatactg cccatgtgcc tgatggtatt aagtattcat gagtatcttc taatacaggc
    48421 ttatctgttg gagcagcaat ataataatct aaacccttac tatttgtaca cacactaact
    48481 ccaagcaatc cacaaggttc gttatttatt aactctgaaa gtttatcaat tgttccattt
    48541 tttatgcatt tagcccataa cttaggaact ttctcaaaac actcttctac aatcatgttc
    48601 atactttctt ttataccaac aatacgaaac cctttctttt ctacaatacg atattgcatt
    48661 tctatatttc cttttacata aatgcttaat gtcatcttag gatatgcttt taaaacaaca
    48721 ccctttgctc tagctgcaga tggagaaatg ttatgtatat tttgaaaagc tctattaaaa
    48781 gatgttggtg aatcgtaacc atacttctca gatagttcta aaattttgat gttactgttc
    48841 tgaagttcaa atgcagcctt agtcatacgt cttcgtctaa tatattcaga taatggtact
    48901 tctgcaatat atgaaaacat tctttgaaaa tgaaaggttg aacaacatgc aatttttgct
    48961 gcttctgcat aatccactcc actttcgaga ttttcttcaa tataagtaat agcttgattt
    49021 aatttattta tccattccat ttgatattac ctccaagcaa attatacagt ttaataaaat
    49081 aatatacctc tctattcatg cacaaaattg taagcattta aatttataag catttttcaa
    49141 tcaatacaat aaatataaaa attgtattat acaataaaaa agttcaataa cattatatta
    49201 taaaatgtta ttgaactttt tataaaaatt aatttaagtg tagttaaatt aagtattaca
    49261 ctatcttata tattacaata tcctactatc ttatagtctt ctggcacttt ataatctttg
    49321 tctggagtac ctaaattcca ttttaaatca aacatagttg cacttattat tgttgcaaaa
    49381 taaagcataa ctataccaat gtctattttt tcttcatata aattagtatg accatctttt
    49441 ctaacagcta aaactacagt gcctccatca actataaatc tccatggttg tctatttaat
    49501 gtagatggag ctaatcttgc atagtgaaat gcatcaagaa gtgctctttc ttctaagatt
    49561 tctatacttg caacatttcc ccattcgttc atataaacaa catcttctac acctagtcta
    49621 gtagacccct tatctgttac aacttgcata tcagattttg aataattttg cccagttttt
    49681 gtagcattta atactttagc attacttaca ttttctccat atccaatagc tataattcct
    49741 gttacctctt tatctgaatt aattccaagt ttttctttta ccttttttcc atcttcaaaa
    49801 gtaacccaac aagaaccaat tccaagttct gttactttaa agattatact ttctcctatg
    49861 taccctgaat tttcaatgta attatctttt atgtcagata atattataat ataacttgga
    49921 gaatctatca tatttccttt gtaccctgct actttatcta aattattaaa aacttcactt
    49981 ctattcataa ttcttacatc aacatctatt tctggaacta gtttcttaca agattctgag
    50041 tatttcttaa tttcactaag atattcttct ttaatatctg tgttcttata ttctctaaca
    50101 gactttctat ttaatatgat tgttttataa tccataattt tatcctcccc aaactagtat
    50161 tgtcttaatt atatacccat taatatatta ttttactcat ttatttaata aataaagatt
    50221 acaattttgt aattattatt tattaataat attccacttt tacattaata atgaccagtt
    50281 gtgcaaaatc cattgccaac caccaaataa aaacatatta taaaggtaat ataaaataac
    50341 aaacaaatct taacaaaaaa ttaaactttt tttacacgaa agaaggcttc ccgttgcctt
    50401 ctttattttt ataaaaaaat aagctgtttc taaaatgatt tcacattttt gaaacagcca
    50461 agttattcta taatgacaac tataatttga ggatgtgagg gagagttgtc attataaatt
    50521 tagggtaatt atattatgtt ttaagctagt tctttctata tttatataat acattttata
    50581 tatgaatttt atatgagatt ggtataaatg atatatgaaa ttacatatgt ttatattata
    50641 ttaaatttta ttattacatt ttccacaaca atactcatat gtctccacat tatttggaat
    50701 atttacaaat acaaattctt tacagttctc acaatacttt aatatagata tagttccaca
    50761 agtgtaacat tcaaatatta cacaatcctc attttcctct actatttcaa actttttact
    50821 atgttcacca cactctgggc acttgtgatt atttacattc ataaatactc ctccttatta
    50881 gtatagttac atgtcaaaaa cttaattaat gtattctata ttacttatta tatattctat
    50941 aataaatcat attctaatat aataaaacaa attaaataaa aaaaaaccat aaattttaaa
    51001 tttatggatt aattcttgta atgataactc tatttgagga tgtgagggag ggttatcatt
    51061 acaatagggt attatattat ggtttttaag ctagtctttc tacacctcat atgatacata
    51121 tgctatatga attttatatg atttttacat aaatatttta tgaaatttaa attttttagt
    51181 cattttgaaa tttgtaaaaa gttctctaaa aatccacagc atcataaaca gccaaaattt
    51241 aagtaaaaca tcataaaaaa atttgtccaa taattttaac aagtaatctc acctcattat
    51301 aattattgac acaaacttaa ataaacaatc tataaatctt ctataaatct taaactttcc
    51361 ccctattgat acacaatttc tagtttgtca attttatttt gcatttctaa gaaaatttct
    51421 tcaacagaat tgttaaatat attgcctaaa tagattcttt tatctttttg aaatgaataa
    51481 gattttacac taccatcaga agaaatatat aaatgactcc actctgctcc atattttgaa
    51541 aacctctcct ttgtatcttt aaacctcata tcttctattt ttattgcttt ttctctgtct
    51601 cctcttacta cagtgtgacc cctttttatt aaactggtta tttttatatc ttcttttaat
    51661 ttaatacgtg tatcatcatt ttttgaatat actttccata tcactttatg acgataatta
    51721 tctaattcct ttattaagct tctatcaata gtaaaactat ctttagttac cacaattaaa
    51781 tcaaaatggt ctaacatata ttgaaatatt tctctcatac ttttattttt taaaatatcc
    51841 tcaccaataa cctctataaa tctacagcct ttctcataca tgcagttcaa taaacttgtg
    51901 atttcagaaa aataatcatt tgtattatta tctccatcta tttctatagt aaagtacaaa
    51961 ggagtaatgt atgatttatt tcctgttatc tcaaatacac ttgatagtgt ctgtatatca
    52021 tcttcaaacg ttaagtatac attctcataa aacataaaaa attccataac tttttctttc
    52081 atattatgga tatttctata tctattggat aatatattta ttatatcgtc agtagtattt
    52141 ttcccatcac attcagccag tataacaatt tgcttccaac ttaagctatc cacatttccg
    52201 atactttttt tatatccatc ttcttcatca taaatagggc caattataat gttttctttt
    52261 ggccacagat gaaccctagt tccatctttt aatttcggat atttattttt tacagactca
    52321 taaaatctac ttgtatcacc catgattctt tactaccccc catagtttaa atattctatg
    52381 ctaaaaatag cactttattt ttattaattc aacaattatt caaaattggt cattatatat
    52441 gtttaaatgg atttaacatc aaccttattt atatgttatt gatgtttata tatgttatat
    52501 aaaatcttat ttctcatact tcaatgtaat cttaactatc tctggtttac aattaagcct
    52561 aattaaaact tttgagcctc ctaagccttt atttaaaatc atagtgctat tatctttttc
    52621 atattttccc cagtcatact taggaaagaa ctctctattt ggagataata cacctccaac
    52681 aaaaggtatt cttattatac ctccatgaac atgtcctgct aaaaccaaat ctgctcccca
    52741 ttttgcatat ttttcaaaga aaaatggtgt atgtgctaaa agaatgttat attcattttc
    52801 attaacttta cctagattgt cttctacaaa attgtcactt agttctaatt ttttgttatt
    52861 agcaaataaa tatggatagc attccaatgg tataattaaa ccatataaat taagatggct
    52921 attacctcta tatattctta cagattcatt ttccatattt attattttct ttgaatatag
    52981 ttccttaaaa taatccttat atagatgttt atactttttt attaaagatt tttgttcatg
    53041 atttccaatt atatgatata cttcatattt ttcaaccaaa ttatctatta aatctaatgc
    53101 aacttgaaaa tttttatttt ctccatctac taaatctcct gttataaata taacatctgg
    53161 gtttaatgat tcaattttat ctatcaatac cttattattt ttatcaaaca ccttattatg
    53221 taaatcactc acttgaacta ttttaaagtt atcaaattcc tttggaattt ttttgttgaa
    53281 aatagtatat tctgtcgttt ctatatgctg agtttcatac ttatacagaa tatacaataa
    53341 tattaatact aatactgtca ttgaaacctt tataatcata ttctcttcct ctttattcta
    53401 ttttgttaat attattataa tgcttttatg ttttttttaa aacaataaca tcatcacata
    53461 catataaatc ttttcgacat tataaaaata agttatcctt ttctaaaatt ttcatttatt
    53521 ttagaaaagg ataactataa aattatctat aaacctctat attgtgaaat atagtttttc
    53581 ctttatttaa atttttatat atatgctcta aagttccatc aaacctaata gaatgtccag
    53641 actctaaaat ataagttttc ccatccacat taaggtcaag tttaccttct attacgagca
    53701 catactcttc taaaacatga ctatgtgtag atgaaacatg agtacagttt tcctcaagct
    53761 caattataaa aagttcaaac cttctttgag ggctaaaagg gtatattgga tataacttca
    53821 tgttcccttt ttgctcaaca ataggctcta cttcttcttt ctttataacc tcataggtat
    53881 ttgtattttc atttaatagt gtagtaaaat ttattttaaa tccagatgaa attttccata
    53941 aagtagatac tgtcggactt gattcacctc tctcaatctg tccaagcatt gctttactga
    54001 cacctgtcat ctttgaagct ttgtctaaac ttatgcccat ttcttgtctc aataacctta
    54061 aattttctcc cacattagga aatttattat ccatgttaaa atcctcctga tagctatttg
    54121 tattctatga tttttactcc tgtaagttct actatctctt ttaattttaa catatgattg
    54181 ttacaaattt catcaaattc atatatataa tcttcaagcc ctaatgcctt atatttatcg
    54241 attccaaatt tatgatatgg aagtaactcc atcttgcctc ctggaacatt ttgtttgaca
    54301 aataatgcag tatttcttat attttcttca ctatcattta ctccataaat aattggcact
    54361 cttataacca tagatttatt caactttgaa agcctacata tattatctaa tataatttta
    54421 ttacttactc ctgtatattc tttatgaata ttatcatcca tagattttat atctacaaat
    54481 atgtggtcta ttttctcaaa tacatcattt accttattcc aatcaaaata tccacaagtt
    54541 tcaattgcaa tatttatgcc tttatcataa aaaatatcaa ctaattctct taaaaaatca
    54601 atctgaagtg taggttcacc tccagaaaaa gttatccctc cattagattc aaagaaaaat
    54661 ataaaatctt tttcaacttc ctctactatt tcttcaacac tcatttcttc ggtcattata
    54721 caaatggcat ctttaagaca taccttgata cactctccac ataaatcaca tttattattt
    54781 atttgcgctc tatcaaatag tgaacttata ttttgaggac aaacatctat acatctatta
    54841 caggatacac atttatcttt cataacacct aattttacta tgttactcca ggaatctgga
    54901 ttagaacacc acttacattt taatttacat ccttctaaaa atatagtagt ccttattcca
    54961 tctccatcat ttactgaaaa atgttgtact tttacaactc tacctttttt actcataatc
    55021 tacctcataa ttaaaaattg ctatgtgaat ttctagctat tatagcatct tgcatttctc
    55081 ttgataaatt aacaaattga gtactatatc cagcaactct cactaataaa tctttatatt
    55141 catctggatt ttcttgagct tttaatagag tatcatttga tatcgtatta aattgtacat
    55201 ggaatcctcc taaagcaaaa tatgatttaa tcatagatgt tagatttcta agtcctcttt
    55261 cagtttccac caaatcttga ttcagtctta aatttagaag tgttccacca gtatgaacat
    55321 catgatttat ttttgatgca gatttcattg ctgctagtgg acttgttgta tcagtaccaa
    55381 caaatggaga aactccctct gtcaaaggtt ttgtcgcttt tcttccacaa ggagttgcac
    55441 ctactatttt tccagttggt acatagtttg atatacccat aaatgcacta ttaaatttag
    55501 agccaaaaat atccttgtat tttctagttt cagtataata aaaatcagaa acttcaattg
    55561 ctaatgaatc tacataatca ttatcatttc catacttagg aacatccaac gcaagttttc
    55621 ttaattcttc ataaccttcc caatcattat ttagtgcttt tgttaattct tctagcgtag
    55681 tcaccttatc ctcaaatact aattttttta tagctgccaa tgaatttgaa actacaccta
    55741 accctatacc agttaataca ggacctatat tatattttgc tcctccttta cttaaatcaa
    55801 ctcccttatc caaacatcca tctacacaag tagataaaaa tggtcttggt accatttctt
    55861 tatgaatttg ttgagcaaca gtagttccta taacagaact ttttacaaga tatgctaatt
    55921 gctttaaaaa ctcatcctta agttcttcaa aagaagtaaa ttctgtgata ttttttgtat
    55981 ctaaccccat tttttctcca gttaatctac tcttaccttc attcatagca tattctaaag
    56041 ctgctgcaaa attgatattt acggctgaag tccactgtcc tgtttttcta aaatgaggaa
    56101 ctacacaacc acagttactc caatctctag catcttctgc atcatatcca tcttgtagta
    56161 acatttgtgc ccctgcacta tcgctgtgta tagcagggaa accagttcct tgttttacca
    56221 atttagcaac tgccattacg aaattgtctg gtgctccttg actcactcta acacttaatc
    56281 ctggctggtg agtttttaca ctttctgtag cctttaaaca catatatgag atatcattcg
    56341 ttccatcagt accatttctc tttttaccac caacagtaag attttggaat tgattatatc
    56401 ctgcaaagta atttgctgta tttgctgata tagtccatac ccattctgat aacttaatcc
    56461 aaagtgcttc tatcaattct tgagcttctg attcagttat tttaccttct ctagcatcat
    56521 tttcataata tggatacata tattggtcaa atctacctaa atttaatgcc aatggatttt
    56581 ctgatagaat accacctaat tgaacaaacc atacaaattg tattgcttca taaaaattag
    56641 ttggagggtt tgctggtaca ttcatacata tctctgaaat ttttataagt tctaactttc
    56701 tcttttcatc tgtttcttgc ttactcatct cttttgcaag atttgaatat ctttgtgcca
    56761 atgtcataat accctgtgca actatagaaa cagatttgta aaaatctatc ttttcaatat
    56821 tttctgaaac tgatatatct aattctttaa tttttttatc tgcatcttcc ttaatccctt
    56881 tatatccttt tacaaacaat atatcttgat aatctggtgt tacttcacca actgcctgtc
    56941 tccacttaga atcattatct attattcctg tatctactaa tatcttagct gtatcttctg
    57001 ggattcttgc taagaaaact tcttccaaag attttccctt ccaatatgga aatatttctt
    57061 ttcttataaa ttctatttgt tcttttgata ttacatatgg gtcttgagtt cttttatcaa
    57121 aagtatccat ttctttgtct acccattgcc aagaaaactc tggtgtcaat atccctgttc
    57181 ttctaaattt tcctgctgta cctactatta attcattttc aaagattttt ataggaagtt
    57241 ctttacatgt ctccaaaaaa gctttagctc ttcttataca gatagcttct ccctcagttt
    57301 ttttatgtga ttctgtaaaa attctagccc tttcacaaca tatcataggt ttagaattaa
    57361 tatattcttg tctaaatgct tctattctat tagtttgact catttaaaat ccccctttgg
    57421 ataatatata ctacattttt gtatgttata acatacttta attatattat actgtccttt
    57481 agcataaaat ggaagcaaaa taacttattt tttttcatct accttgaaca cctatatatt
    57541 aatacttttt ttgttaaatt tataaaatct aaaaaaattt tctatgatat attttctata
    57601 ttgttatagt tatgtctaat atactaatga tttgaaatat caaatttgta tactagactt
    57661 agttttaaaa ccttagttga ttgtttaact ttgttaactt caacatgtat atccttcata
    57721 taaggaagct ctacaacacc tactccctta ttaaagtctt cttcaaccat agaaaaaatt
    57781 tctttctcag ttaagttcgt atcagtcaat gatttaaata aattgtatat aaatttaaca
    57841 tatttatcac tctcagataa cttatcatct tctggatact ctttagcaca gagaatatct
    57901 attgttactt ttccttcttt atcgtcttca gacatagaat agaataaact tcgaatattt
    57961 ttttcaggtg gtttttcagc accatttata gatactacaa agctaccatc tgattttgag
    58021 ttagtaatac tataaccact gtctattata gctttcgaaa atctttgaga taaatctttt
    58081 tttacttctt ctctaccttt cgcatcatta atcttttgtg agtaattatt aaatagctca
    58141 atagattcat cttttttatc ttcaacttgt tctttcaatg aatctttact aatttgttct
    58201 gagctactta agttcttatc agatacagga gacatacacc ctaccatcaa tgctaagcta
    58261 agatttaaag ccacaattat tgccactcta tttatattcc tttttacttt catacacaat
    58321 cctcccatca cactaaccgc tctaaagtat tattcattgc actagaatat atttatattt
    58381 tctttatatt aaagatttat tattcaatac atatcacctt cctatccaat tcttataact
    58441 tactattagt aaaattataa gctccttaat acagaaataa ggatgttatc ttttgttatt
    58501 aaaagataac atccttattt ttttgtatca atacatatgt cccaactggt aacttaatcg
    58561 ccccaactgt cagtatcttg gtccaatggt atatatatat ttagtataaa tttatcgata
    58621 ctattttcaa ataataattc tccattatat ttttgtaaag aagatttaat actctgaata
    58681 cctattccat gtacgaactt atccattttg tttgttaaca atatattttt attaaaagta
    58741 agctgattta gtttactatt ttcacattta agtacaaaaa atgaccttgt tatagttcct
    58801 ttaattctaa tatatttatt aatattttca tccactattt tatcacatgc ttctattgca
    58861 ttatccaaaa tattagaaaa tatgcttgac acatctatag gttttacaaa atttactttt
    58921 gaaaaattta tagagcaagt aaatttaatt ccttttttta aacatacttc actcttttcg
    58981 ttgattataa tgtctaatat catatttcct gtattataga tatatttaaa tgtttttatt
    59041 tcatctttta aattgttaac atattcatta atttctttgc tattgtttct aaggttgtct
    59101 atacaataaa tgtgattatt tatatcgtga tatagtttct taactcgcat atgagattct
    59161 tgaatactta aataatgcgc atattgcata tctaacttat tttttattaa ttcagcttga
    59221 gattttaatc tattctcttt tattatttct ttaaacaata gtataagaaa tatactacta
    59281 gctcctacca attttggatt aacaaaatta tcaaaatagt atccttctga atgtaatgac
    59341 ccaaaccgtt ctaatttttt taatacataa tttacaagca tattcattgt attaactaat
    59401 aaggcaaata ataaatatac ataatttctc ttatcttggc taattaattt tatagacttt
    59461 ctaaaaaagc taaatataag atatataaga ataattatta aattactata tatctgaatt
    59521 tttatagatt ctaagtgagg tactaataaa gattctttag atgaaataac attacctgta
    59581 attgcaaaaa atagtattct atatataaca gcatccaaac atttataata tacactaaat
    59641 agataaaaga aaatggaata cttaatataa cccatcttat aaaaataatt atagtatcct
    59701 ccccaagcaa taaatgctaa tatataaaat aaatagttta tattactaaa gtaatttcct
    59761 ccattaaata atctacttat ctgaattata atataaataa gaaacaagac aatatagaat
    59821 actatttttt catttttttt actatccttt ttataaatta aaattccgtt cattatagaa
    59881 aactgtataa atatagataa aactactaat agctcagtca taaagtttag catattgtat
    59941 caccaagaaa ttttaaaaat ttctccttaa cttctttata tctatatcta ctaataggta
    60001 cctcttctcc actttccagt attgcagtat taggctttat attttcaaca tatcttaaat
    60061 ttactataaa acttttatgg catcttataa atttatatgg atttaattct ttttctattt
    60121 tgcctaaact atattttata tcaaaattct tgtttattgt gtgtattagc atatcttttt
    60181 tttgaacttc tatatatttt atttcattta aataaatctt atatgtatta gacttatttt
    60241 ttattgtaat atgactttcc ttatttattt caatatcttt gatacaagtt agcacatgtt
    60301 tttttagttc ttccaactct attggcttta gtaaatacct ataagctctt acctcataac
    60361 cttcttgcac ataatctatt aatgaagtta caaatattat ttccatttca ttgtctactt
    60421 ctctaatctt tcttgcagta tccattccat ttagtttttc catttttata tcaagaagta
    60481 atatatctat atcttttaaa ttactttcca gtaactcttc tccagatata tacttttgta
    60541 tctcatattc tatacttata tcttttaata tattctcaag gtaatcttct attaaaagtt
    60601 gtgtttcttt ttcatcttca caaactgcta tcttaatcat aaaatgcctc cttacataat
    60661 ttctagttaa tacaattaaa atatttataa tatatttaaa gataattttg tatatctgat
    60721 actttaggat aacattttta aattattttt atcaatactc aatcccacac aactattatt
    60781 tgatatttca atttaaagac agaaattact ataattaaaa acagtactta ctgacaaaag
    60841 aagatgtctt aaaatattaa aaaaataatt ttaggacacc ttcttttatt tatttaaact
    60901 ttttaagcct taaataatac attaatctcc tatataattg tactgcatat aaaatcaaca
    60961 atataatctg tagtacaata gcagttacag atgctccata accactatat aaatttctta
    61021 tttcaatatt caataaatat ataaatatta ctactaacat aaagaatata aacatattca
    61081 taaataaaat tgactttact ttatttgttt tatcagaatc actatataat ttaggaggta
    61141 tgtctttgta ttctttcgac catatatacc atgcagatgt acccataaaa ctaccaatac
    61201 tcctaaatac aagattccag ccatttgatt tatgttcatc aaaataatta ttctctacat
    61261 catagtagta atcaacagtg tattttattt ttcttggact tcccttatga aaataaaata
    61321 ttcctccaaa tttatttatc ttatataaat tatatccttt agcttcaata tcttctaacc
    61381 atttctctat cttatcaggt gaactatacc agtcaaattt gaattttatt ttcttttcca
    61441 tagcactcat tctccaaaat gatattttta aatagcttaa aaatctattt aaataattat
    61501 atcattttga tactaatttt aggttacaat catatattta aaaagctatt taaatagtaa
    61561 taaactaata gccataacac ccattcctgc aatcaatcca taaatagata aatgatgttc
    61621 cccgtactct ctagctgatg gcaataattc atctagtgat atgaatacca taattcctcc
    61681 tacaattgca aatacaattc caagagttat atcatttaaa aaatttctaa gaagtacata
    61741 tccaataatc gctcctaaag gctcagacat accagataaa aaggaataat aaaaagcttt
    61801 ctttttatct cctgtggcat aataaactgg tacagataca gatatacctt ctggtatatt
    61861 gtgtattgca attgcaattg ctatcggaat agctattgta acatcatcaa gagctgatat
    61921 aaatgtagct aatccttcag gaaaattgtg aattgctata gccattgctg taaatatacc
    61981 tgttctcaaa agagacttat tttttttgat attcttttct tctatattct ccattttctt
    62041 tatttcatgt ggattttctt cttgtggaat tagcttatca ataacagcaa tgatagccat
    62101 acctataaaa aaagctatta cagttgacca acttcctaat ttctctccca tagattttgt
    62161 caaagcatct tgtgctttag gaaaaatttc tatcatagaa acataaatca taacaccagc
    62221 agaaaatcct aagcttatag aaagaaactt agtatttgtt tttttagcaa aaaatgctat
    62281 acaacttcct ataccagtag ataaaccagc caataatgtt atcaaaaatg caaatattac
    62341 attattcaaa taaatcacct tctttttaat tgatattgat tatcattttc tttatgctat
    62401 catatatatt ttatatagtc aatatttata aaaaatatac acaataaaaa agcagagata
    62461 taaacttagt ctctgctttt tctttatagt atattaaaat tatttattta agaaatccac
    62521 tgcatattgc acatataaag cagttccaat ttctagagca tcttcgtcta tattaaagca
    62581 tccatgatga tgaggataac aagcaccttt tgactcattt ctagctccta caaatgctag
    62641 tgcaccaggt gctatattca taaactcagc taaatcttct gctcctgtta ctttttcaaa
    62701 tagtgttata cagtcttctc caaatagctt aattgctgca tctgtagcta tctttgaaca
    62761 ttctttgtca tttataactg ctggtgttaa gtacccatac tctaattcag catctgctct
    62821 atatgcttct gctgtagatt ttgctatacg ttctaaaatt ccaggaattt gctttctaag
    62881 ctctggatta aatagcctta ttgtaccttc taagacagct tcactcgcaa ttacgttaaa
    62941 tctagttcca gaatttaaaa ctccaacact cacaactaat ggttccagag gacttacttc
    63001 tctactaacc atagattgta gattcataac tattgctgaa cttgcaagca ctgcatcaac
    63061 accttgatga ggaagtgaac catgaccacc tctacctttt acagtaattt taaagaaatc
    63121 agcagaagcc attcttggtc cttcttctac cgatatggtc ccagattcta catcagtcca
    63181 aagatgtatt ccaaacacac tatctacacc ttccatagca ccatcttgaa tcatagctct
    63241 tgcaccttta ccaacttctt ctcctggctg aaaaaataat tttacagttc cattgatact
    63301 atccttaata tcatttaaca cttttgctgc ccctagaagc attgatgtgt gaccatcatg
    63361 accacaagca tgcataagtc cttcattttt agatttgtat tctacatcag tgcattcaac
    63421 aacttgtaga gcatccatat cacccctaag tgctacagtc tttcctggat tagctccttt
    63481 tatagttgca attacacctg tacctccagc tgatacatat ggtatcccta ttttatcaag
    63541 ttcttcttta actctctttg atgttctaac ttcttccata cttttctcag gattttcatg
    63601 aaattccctt ctaagcttaa ttacatagtc tttataactc tttgttattt ctttaatatc
    63661 cattccatac ctccaagtag tacacattct tcttatttaa aatacttttt atcacttaaa
    63721 tactatatta gatttacaaa gatacccgct attactacag aagctattgt aactgtagta
    63781 aatcctccaa caagcatctt tggaagcatc ttatccatta aaaattcttt ttcttctggt
    63841 gtttcagcca aagcctttac tgcctcttca gttaatatat agtttggtgg aaaaccataa
    63901 agtgatgtaa gcgaaactga aaaagccatt tctttacttt cacctaaaag cttacctact
    63961 ataatagaga atattcccat acctattaca ccaaatatta tgattcctac aagaggaact
    64021 gccatttcaa caagcattgc tggtgtagct tttgctaacc ctgcaaatat aaaagccatc
    64081 aatgatgtca ttaaccatcc aaatgaacca gatttattaa gtggttttct atcaactatt
    64141 ccaagttctg atgctattac accaaatatt aaacatataa catatcttga tacaacttca
    64201 tttgtaagat ttgtaaattg tactgctaac catgctacaa atcctaatct aagtattatc
    64261 atatatgtcg tatcatattt ttctggtaag tctggtatta tcttaaatct gcttttttgt
    64321 tcaggtaaat ccttaacttt ttcttcatct gtatttacag ttacttttcc acttctaaag
    64381 tctgataaaa gtctttttcc ttctttttta agcattaatg ctgtaatagg ataacccgca
    64441 aatccttgtg caacatacat caaaattgca agtactgata aacttgcaag accttttgct
    64501 gtagcagcat ctgccatcat tatagatgca actagccctc cagtaagagg aggtgtagct
    64561 attactgctg tatcccatcc aaatactact gtccctaatg ccaaagcacc tacacatatt
    64621 cctactattc ctgccaaggc tattactatt gttttccatt gacctgctaa ttccttaata
    64681 ctcatcatag ttcccatatg agttattaac aaaagcatac ctaattgagc taatggtgtt
    64741 cctaaagcgg ctaagtccac aatattttct gggaaaaaag tccaaaatcc tactataaat
    64801 ataattgctg atacaaaaac cgacggaaca aaagctttag tttttgctga aactatatct
    64861 cctatcgtca gtgatactaa aactagacaa aaagctgtta ttgcctccat acaaaatccc
    64921 ccctcataat aaatatattt ttataaaatg tatgtatagt tatccattat tttactactt
    64981 ttgaaaaaca tttcaagtca aaattcgatt tttttcataa aattcgataa attccataaa
    65041 ttaaagttag ttttctaaat tattcttttt gtaaaaacgt tatcccgacc attggctatt
    65101 taactctatt cttacaaaga gaattaaatg taatttgcaa aaaataaaac ataggataca
    65161 ttttattcat aaaacatctt ataaatataa aatgaattgt ctttatgaat cttaatatat
    65221 cctatgtttg taagtttaat gtgtatgtta gctatggtgt aaaatttgta tactagttat
    65281 tgtgtaacct actatatact ccatttttgt ttactagctc ttcatgagta cctctttctt
    65341 caattccttt atccgtcaat actatgattt catcagcatt ttttatagta gtcaatctat
    65401 gtgcaacaac taaatttgtt ctatctttac ttaattcctc taaagactct tgaatttctc
    65461 tttctgttac attgtctaaa gcagatgtag cctcatccaa tattattatt ggaggattct
    65521 ttaaaaagat tcttgaaatt gaaattcttt gtttttgccc acctgataat tttacgcctc
    65581 tttctcctat ataagtatca tatccatctg gcaaagtctc tacaaagtca tgtattctag
    65641 cttttttagc agcagctatc atttcttcat ctgtagcatt agggttccca caaagaatat
    65701 tatctcttat agttcctgta aataaaaata catcttgttg aactatacct atattttttc
    65761 tcaatgattt taaactaaca tcttttatac tctttccatc aatttttata tcacccttat
    65821 caaattcata aaatcttggc aatagattac ataatgtagt ctttcctcct ccagaaggtc
    65881 caactaatgc tatagtctta ccagctttta tagataaact taaattatcc aaaacttgag
    65941 tcttatcttc atatgtgaaa gatatatttt ctatctcaat gtcacctttt acattttcaa
    66001 gttcaatagg atttttagct tctttttgat ggtcttgttc cattatctct atgaatcttt
    66061 taaaacctgt cataccattt tgatattgct ctgtaaagtt tattaatttt ttcataggtt
    66121 gtataaacat ttttacatat agtatataag cagcaaaatc acccaaagta atctttccta
    66181 tataagtaaa ataaccacca gctattacaa ctacccactc taagatatcc atgtataaat
    66241 tcataccaga gtaatattct gccattacct tataagaatc ttgtcttgct cttctaaata
    66301 atttattgct tcttacaaac ttatttaact cttctttctc agtacaaaaa gacttagtta
    66361 ccttcatacc tgctatacta ttttctaaag tagcatttac atcacctata gtaactctac
    66421 tcttcataaa agcaatattc atcttatctt ttttagctat tgcaaaccaa attataaacg
    66481 gtaatatagc aaatattata agcgtaagag gaatatttat atctataagt ataaagaatg
    66541 aaccaaccaa cattactata gaaatgaata aatcttcagg cccatgatgt gcaagttctg
    66601 ttatatccat taaatcattt actattctag acatagttac tccagatttg ttattatcaa
    66661 aatacgtatt tggaagtctt tgtaagtgtg taaatacctc atttctcata tcagcttgca
    66721 tatctacacc aataacatgt ccccaatact gcataaaata gttaagccct gcttttgcta
    66781 taaatataag tataagtgct actgcaaaaa ctactaacat tcttaagttt ttatttggaa
    66841 caacgtcatc cattatattt ctagttatca taggataaac taaatcacat aaggaaaata
    66901 gaaaagctgc tataaggtct agtgtaaaaa ttttcttata tggcttataa tatttgacaa
    66961 attgttttat cataagtatt aaatccctcc tttattagta cttctattag tacttctaaa
    67021 aaatacccat aaattagtat aacataacaa taactttaaa tcttttataa acttacaaag
    67081 taataactat ctttttcata aaattgaaga tttatatcat atagttgtat acttgaaaca
    67141 acataaaaag agctatatct ctatatttaa aattttataa agatacaact ctatatttaa
    67201 tactaaattt tttttataaa tacaaaacta cttcaatgca tttaatatct ttttatctaa
    67261 tgctgttgta tttatacctg ttatatatcc tgttgccttt attgtaggta tatcataagt
    67321 tgttggtagt atagtagtag atacgattaa atcagcacct tcttgttttg ttgaacattc
    67381 agcaatttta cattgctcaa cttctgcttg tatattattt tctttaacca atctttctac
    67441 tctgtcacaa actattgttg atgttgcgat tcctgctcca caggctacta atattttttt
    67501 catatattgt cctcctacaa tttctttaat attttataac tcaaaataaa attgataaat
    67561 ttcttatatc tttatttata taaataatta tatcatttta tataagaaga acatcttaaa
    67621 attattcttt taatatgttt tttatttcaa cattacttat acttaaaatt tcatttttta
    67681 tacaagactc tatgtacttt gatatatttt tataatcatt taaattaaac tgttcaatat
    67741 tcaatttata ttctatatca ctgacaatac ctatcaaatc agacttatta gataaaatat
    67801 cctcatactt accttttcta gttacttcca atcttttaaa tctataattt ttatatcctt
    67861 ctatgataat caagtccata tcttcatata attgaatcat tttatataat ggattcttct
    67921 cttttagttc ttcaatatat gctactcgtt tatctgatat tatacagact tttctcgccc
    67981 cagattttct atgtttataa gtatcttttc cttcctcatc catatcaaaa tcatgacagg
    68041 tatgtttaat aactccaaca cgataccctt ttttatttaa ttcttttatt atgccttcaa
    68101 tcaacgtagt tttacctact cctgaatatg agacaactga caatatatta tacataaaat
    68161 tgtgtccttt cataaaacta tctaataaca acatccacta attgattttc ttttattgtc
    68221 tcattctttt taatcttaat catacaatta cttcttagag ttgcagataa tctagctttt
    68281 gcatctttct tatcatttag ctctacatac aatttacctt cacttgtata tagttttcca
    68341 cttacaaatc tatctttatt tgaaagttta ttaaattctc ctttaaatat agcttttata
    68401 tgatgtgttc ccttcttata tgttaaatac tcaataacag gaactatcac attatcaaat
    68461 accactattg ctgcatgtgg attaccagaa agaccaaata atagcttttc tcccaatgta
    68521 cctacataac aagctccacc aggtttaatg tttatcttcc aaaataattc tgttgcccct
    68581 atttttttga atacatctgg aattaaatct ttatctccaa cagaaacacc acctgtggta
    68641 attaaaaaat ctacactctg taacatattc tttacctttt tttctaactc caatatatca
    68701 tcagaacaat tgcatattgt atctgcttgt attccaagtt ttaataatct tgaatataag
    68761 gtatatctat tactatcgta tattttacca ttctctaaag tctcatttat atcttgtagt
    68821 tctgtacctg tattcaaaat tccaactttt aaatcatcat aaacagttac tttggatatt
    68881 ccaagacttg ctaatactcc aataccatca tatcctatat tctgattttt attaataatc
    68941 aattgcccct tttttatatc ctcaccctta aatatgtaat tatcgtattc ctttaatttt
    69001 atatttaaag ttatcatatc acctataact gttacatctt ctttttttat tacacaattt
    69061 gcaccctgtg gtatctttcc accagtcatt atcttcactg cttcattttt atttaatacc
    69121 ctattaaata catctcctgc atacaaagtc cctataacct ttaaatttct attttcagaa
    69181 tttgcattat atgcataacc atcatagggt gacctatcaa atggaggact atcaattgtt
    69241 gaatatatat cttctgcaac taccttattt actgcatcta taagatttac tatcttgacc
    69301 ctgtttattg gtaaaacatt tttttcaata atttttatgg catcttctaa ttctatcatt
    69361 ttaaatactc cccaatatat tttttattta agatatttct atgtaatata ttatagatta
    69421 taaaagttgg aaatactttt atcttatatt taattataac taatagttat ctataagtgc
    69481 agttcaaatt ttataaatct aataaaaaaa ctgttcccag ctagaaattt ccttctatct
    69541 tgaaacagca tcatatgctt tagaatattt tattctaata aagttccttt tattattttt
    69601 acaattttat cactttcaat agtttttata gattttattt tgttatccac aatacttatt
    69661 gtaagtacct ctttttttaa tattttgtta tcttctttca atctataact cttaactact
    69721 ttactgcctt catgattata tgctgttaaa tcataattcg catctcctac aatttcattt
    69781 attctggaat cttcaacacc aacatactct cccaggtcaa tatgtctaaa attttctagt
    69841 gatacagccg atttttcatg gtcacttttt tcaatcacta tactagattc agcatcaatg
    69901 actgatatac cttgtgatga gaaagaattg gtttcaacat tgacaacttt attttcgtta
    69961 atatcaacat ataaagcact tccatctagt tcatcatttc cagtatattt tggataaact
    70021 aatgtcatat aacttgatgt atttatatct tgcattgtat ttgattcttt taaaacttta
    70081 ggttttatat aataaaatgt attataaggt atacccatat tctttataat gtacttataa
    70141 tctttattca taatttcatt aacatcattt tgaacttttg tcatagtttt ttgctgtgtt
    70201 gctttacttg ctacttgatt tttctcttta gtattttctt tatgacatcc aacaagtata
    70261 atacctaaaa tagttacaca aactaatgac ctttttaact tcataaatca atcctccttt
    70321 cttaaatttt atagtattta tctatatctc aatttacagt
//
LOCUS       DAEQAF010000007        69911 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.007, whole genome shotgun sequence.
ACCESSION   DAEQAF010000007 DAEQAF010000000
VERSION     DAEQAF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 69911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69911
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.007"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..1098
                     /locus_tag="KRN00_000596"
     CDS             <1..1098
                     /locus_tag="KRN00_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1826482.1"
                     /translation="YKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVYKSDKETF
                     TYKQCSSDLTNLKKKLKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKFKSKKINR
                     FSYKTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGRYYVSLCC
                     TDVDIEVFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQRELSRKTI
                     GSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLS
                     RLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKDLNIREWI
                     CPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            1216..1521
                     /locus_tag="KRN00_000597"
                     /pseudo
     CDS             1216..1521
                     /locus_tag="KRN00_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            1534..2439
                     /gene="truB"
                     /locus_tag="KRN00_000598"
     CDS             1534..2439
                     /gene="truB"
                     /locus_tag="KRN00_000598"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBH1826483.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     NNFLGLGKLSKHNNTISVKSDKMFI"
     gene            2570..3499
                     /locus_tag="KRN00_000599"
     CDS             2570..3499
                     /locus_tag="KRN00_000599"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBH1826484.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            3603..3860
                     /gene="rpsO"
                     /locus_tag="KRN00_000600"
     CDS             3603..3860
                     /gene="rpsO"
                     /locus_tag="KRN00_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBH1826485.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            4100..4945
                     /locus_tag="KRN00_000601"
     CDS             4100..4945
                     /locus_tag="KRN00_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1826486.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            5070..7181
                     /gene="pnp"
                     /locus_tag="KRN00_000602"
     CDS             5070..7181
                     /gene="pnp"
                     /locus_tag="KRN00_000602"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBH1826487.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETLEDFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETG
                     MIPRAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEA
                     RPSRGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTL
                     SLLDAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQ
                     MDIKIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDK
                     IKDVIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVG
                     KTYKGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEID
                     EKGRVNLSRKVLLPKPEHKNK"
     gene            7447..8190
                     /locus_tag="KRN00_000603"
     CDS             7447..8190
                     /locus_tag="KRN00_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1826488.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            8348..9595
                     /locus_tag="KRN00_000604"
     CDS             8348..9595
                     /locus_tag="KRN00_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1826489.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGI
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINSIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            9630..9875
                     /locus_tag="KRN00_000605"
     CDS             9630..9875
                     /locus_tag="KRN00_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH1826490.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            9885..11108
                     /gene="dapG"
                     /locus_tag="KRN00_000606"
     CDS             9885..11108
                     /gene="dapG"
                     /locus_tag="KRN00_000606"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH1826491.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            11221..11955
                     /locus_tag="KRN00_000607"
     CDS             11221..11955
                     /locus_tag="KRN00_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBH1826492.1"
                     /translation="MKDYREDNERFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            12078..14489
                     /locus_tag="KRN00_000608"
     CDS             12078..14489
                     /locus_tag="KRN00_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBH1826493.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDEEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            14492..15550
                     /gene="mnmH"
                     /locus_tag="KRN00_000609"
     CDS             14492..15550
                     /gene="mnmH"
                     /locus_tag="KRN00_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBH1826494.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQSAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            15544..16878
                     /gene="rimO"
                     /locus_tag="KRN00_000610"
     CDS             15544..16878
                     /gene="rimO"
                     /locus_tag="KRN00_000610"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBH1826495.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            16865..17407
                     /gene="pgsA"
                     /locus_tag="KRN00_000611"
     CDS             16865..17407
                     /gene="pgsA"
                     /locus_tag="KRN00_000611"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBH1826496.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNVPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            17695..18741
                     /gene="recA"
                     /locus_tag="KRN00_000612"
     CDS             17695..18741
                     /gene="recA"
                     /locus_tag="KRN00_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBH1826497.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            18917..20458
                     /gene="rny"
                     /locus_tag="KRN00_000613"
     CDS             18917..20458
                     /gene="rny"
                     /locus_tag="KRN00_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBH1826498.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFIRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            20772..23108
                     /locus_tag="KRN00_000614"
     CDS             20772..23108
                     /locus_tag="KRN00_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1826499.1"
                     /translation="MKKNTLLHTNIMVCIIITLGFVATSIIGYQSNTNIFKNDIEHVS
                     TLAAEGIYYQIDKLLSEPINVSLTMANDSLLKNFLDGEKEHLNDEEFIYKLQDYLNVY
                     RNKYSYDSVFLVSTKTNNYYHFNGLDRNLSANNSENQWYYTFLKNDDEYSLNVDNDEA
                     SNNSITVFVNCKIKDDNGATMGIIGVGLKVNSLQMLLKGYNDKFDVVARLIDDKGFVQ
                     LAVDKTGHENINFFENSSSDLSNSKQLILNNKKEQKSFWYSSEKSKSYIVCQYIPSLK
                     WHLVLENDFTLMIKQLHLQFFKGIAVIVLIIIFVLFTITHVLKKYKNQIIKLSVSQKL
                     EYQKLLSKSTEGLYENIFEIDITNNKAGCEDENRYFHEFGLGLNTPYDEALHTIAKNQ
                     IKEEYAQGYLDTFLPENVIKRYNSGINNISYDFLIKKDEESYHWIRINARIFFWTSDE
                     SVRMISYRKNIDKEKNRELLLLERSQRDSLTGLYNKATTEEFIRSFLKNESNQDLEHV
                     FLIFDIDNFKNVNDKYGHVFGDFVISEFALELKSQFREDDIVGRIGGDEFVVLIKDFN
                     NNNYVLIDKLERFCSKINQKKFVEQAEFSIACSIGVAMYPEHGYVYSELYEKADQALY
                     YAKSHGKNSYHIFSEDSIDSISFHIDSRDIKVLLEMATDGVVKFACMENLKLLYFNQK
                     MLEFTGYSAQTVTSIGFDIFSPVLQDDLQMVLDTLREAISKRETFEIVFRFCHTDGHI
                     FPVRMQGKFVSELYQNRYPVFYAIYTDISSINTLLENK"
     gene            23490..25271
                     /locus_tag="KRN00_000615"
     CDS             23490..25271
                     /locus_tag="KRN00_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBH1826500.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(25353..25883)
                     /gene="lepB"
                     /locus_tag="KRN00_000616"
     CDS             complement(25353..25883)
                     /gene="lepB"
                     /locus_tag="KRN00_000616"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1826501.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDENEVLG
                     KVMVRLLPLDNIGKVD"
     gene            complement(25923..26747)
                     /locus_tag="KRN00_000617"
     CDS             complement(25923..26747)
                     /locus_tag="KRN00_000617"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH1826502.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKRPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            27004..27912
                     /locus_tag="KRN00_000618"
     CDS             27004..27912
                     /locus_tag="KRN00_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1826503.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            28056..29501
                     /locus_tag="KRN00_000619"
     CDS             28056..29501
                     /locus_tag="KRN00_000619"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBH1826504.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKDL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            29812..30264
                     /locus_tag="KRN00_000620"
     CDS             29812..30264
                     /locus_tag="KRN00_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1826505.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(30589..31785)
                     /locus_tag="KRN00_000621"
     CDS             complement(30589..31785)
                     /locus_tag="KRN00_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1826506.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            32170..33120
                     /gene="galT"
                     /locus_tag="KRN00_000622"
     CDS             32170..33120
                     /gene="galT"
                     /locus_tag="KRN00_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBH1826507.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            33281..34033
                     /gene="xth"
                     /locus_tag="KRN00_000623"
     CDS             33281..34033
                     /gene="xth"
                     /locus_tag="KRN00_000623"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBH1826508.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(34125..34901)
                     /locus_tag="KRN00_000624"
     CDS             complement(34125..34901)
                     /locus_tag="KRN00_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1826509.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            35216..37114
                     /locus_tag="KRN00_000625"
     CDS             35216..37114
                     /locus_tag="KRN00_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBH1826510.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIDEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            complement(37242..38363)
                     /locus_tag="KRN00_000626"
     CDS             complement(37242..38363)
                     /locus_tag="KRN00_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBH1826511.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            38562..38894
                     /locus_tag="KRN00_000627"
     CDS             38562..38894
                     /locus_tag="KRN00_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1826512.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            38881..39939
                     /locus_tag="KRN00_000628"
     CDS             38881..39939
                     /locus_tag="KRN00_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBH1826513.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            39932..41002
                     /locus_tag="KRN00_000629"
     CDS             39932..41002
                     /locus_tag="KRN00_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBH1826514.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAEFKK
                     ENKLYQEKVNIDKLDIAVDNINVTIKKSSSEDVRVTTRGNNEFYKYNVTLKDKTLVVK
                     GERKYENKIKKIKNFDQLLNTSINSMFSHDYREIIIYVPNNVDINASSISSHLFVYDN
                     VASNTITYKTSYGGFSRAITENKVNRLENLNLISNNNLHLSTKSILGVKNVNIESESL
                     YISSENEDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHNEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            41104..41640
                     /locus_tag="KRN00_000630"
     CDS             41104..41640
                     /locus_tag="KRN00_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1826515.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            41756..42463
                     /locus_tag="KRN00_000631"
     CDS             41756..42463
                     /locus_tag="KRN00_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1826516.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGQ"
     gene            42465..43181
                     /locus_tag="KRN00_000632"
     CDS             42465..43181
                     /locus_tag="KRN00_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH1826517.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTIFLPGALTLISSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYMFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            43183..43941
                     /locus_tag="KRN00_000633"
     CDS             43183..43941
                     /locus_tag="KRN00_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH1826518.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSGIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            44076..45464
                     /locus_tag="KRN00_000634"
     CDS             44076..45464
                     /locus_tag="KRN00_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBH1826519.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGSLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVCNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLYIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(45540..46361)
                     /locus_tag="KRN00_000635"
     CDS             complement(45540..46361)
                     /locus_tag="KRN00_000635"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBH1826520.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIHIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            46597..47766
                     /locus_tag="KRN00_000636"
     CDS             46597..47766
                     /locus_tag="KRN00_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBH1826521.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSDDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            47950..48150
                     /locus_tag="KRN00_000637"
     CDS             47950..48150
                     /locus_tag="KRN00_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1826522.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            48571..48999
                     /locus_tag="KRN00_000638"
     CDS             48571..48999
                     /locus_tag="KRN00_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBH1826523.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(49142..49897)
                     /locus_tag="KRN00_000639"
     CDS             complement(49142..49897)
                     /locus_tag="KRN00_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1826524.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(50598..51104)
                     /locus_tag="KRN00_000640"
     CDS             complement(50598..51104)
                     /locus_tag="KRN00_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826525.1"
                     /translation="MNNLDKLFELASQEGIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            complement(51186..51506)
                     /locus_tag="KRN00_000641"
     CDS             complement(51186..51506)
                     /locus_tag="KRN00_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1826526.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            51675..51872
                     /locus_tag="KRN00_000642"
     CDS             51675..51872
                     /locus_tag="KRN00_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826527.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQL"
     gene            51976..52416
                     /locus_tag="KRN00_000643"
     CDS             51976..52416
                     /locus_tag="KRN00_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826528.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            52665..53108
                     /locus_tag="KRN00_000644"
     CDS             52665..53108
                     /locus_tag="KRN00_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826529.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPVMLNTNNKDIVISIKYLPKPQSKSIRMYEVSDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTLTLNYLDSVYEEDIVYENMEEINLNLGE"
     gene            53113..54177
                     /locus_tag="KRN00_000645"
     CDS             53113..54177
                     /locus_tag="KRN00_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBH1826530.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIN
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            54191..54619
                     /locus_tag="KRN00_000646"
     CDS             54191..54619
                     /locus_tag="KRN00_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBH1826531.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            54745..55191
                     /locus_tag="KRN00_000647"
     CDS             54745..55191
                     /locus_tag="KRN00_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBH1826532.1"
                     /translation="MSENGLLKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            55218..55385
                     /locus_tag="KRN00_000648"
     CDS             55218..55385
                     /locus_tag="KRN00_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826533.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            55385..57838
                     /locus_tag="KRN00_000649"
     CDS             55385..57838
                     /locus_tag="KRN00_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826534.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            57838..58260
                     /locus_tag="KRN00_000650"
     CDS             57838..58260
                     /locus_tag="KRN00_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826535.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            58542..60071
                     /locus_tag="KRN00_000651"
     CDS             58542..60071
                     /locus_tag="KRN00_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1826536.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGTVTLSVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            60087..60413
                     /locus_tag="KRN00_000652"
     CDS             60087..60413
                     /locus_tag="KRN00_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBH1826537.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            60413..60841
                     /locus_tag="KRN00_000653"
     CDS             60413..60841
                     /locus_tag="KRN00_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBH1826538.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            60834..61886
                     /locus_tag="KRN00_000654"
     CDS             60834..61886
                     /locus_tag="KRN00_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBH1826539.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTVI
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYFRDIRGEIIYTKVMGILINTTGVHDLSNLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            61883..62581
                     /locus_tag="KRN00_000655"
     CDS             61883..62581
                     /locus_tag="KRN00_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBH1826540.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            62582..63565
                     /locus_tag="KRN00_000656"
     CDS             62582..63565
                     /locus_tag="KRN00_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBH1826541.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            63582..68903
                     /locus_tag="KRN00_000657"
     CDS             63582..68903
                     /locus_tag="KRN00_000657"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826542.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDLKNIV
                     AKSIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTMVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSGYVNGLSNKSASQYT
                     EIGVSNVTDAYSSYNATFIVADEKKVYATGINTNYLLGVNPNDGVNINLTLINNWFYV
                     NPSGASYSTNSCTNDITKINNIIIYEYMAILCTNYGSFLTGYHGTLWTKPSDSTYRVQ
                     QQGITHAGYISNYIYNYYPTRCTQSSYSTNFAYLYYGESTSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFAKINIDNIKSISVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNVFTKINVENVKYVTVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGFVNGYFGFTESSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSITNNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDEYYMDIPVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     HRYDNDKNEALEGSLHSYFKTDNTSDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIF
                     KDNFKYTSIILPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTFT
                     EVNISDVKKVACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVK
                     DISIYNSMTLVLTNEGELYAQGYNTNGLFGLGESEKDKIITTFTKVLTNVKEIKSHND
                     DHILVIKNDNSLWITGKNKSMYKISISITDLYEFTKIPVPEHLNDILDIELSDDTIYM
                     ITKVDTSKASIEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIVFE
                     IPQNKIVLGENKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINIT
                     ENNTDLIVTLNEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSY
                     QEIYELEEANIKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            68920..69273
                     /locus_tag="KRN00_000658"
     CDS             68920..69273
                     /locus_tag="KRN00_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826543.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            69536..69796
                     /locus_tag="KRN00_000659"
     CDS             69536..69796
                     /locus_tag="KRN00_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826544.1"
                     /translation="MDKLITELSSLVAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTDIKGMLQNGV"
BASE COUNT        28101 a         7493 c        12102 g        22215 t
ORIGIN      
        1 tataagttta gaatgtatcc aaataaaaaa caacaagagt taattaacaa aacttttgga
       61 tgttgtagat ttgtatataa taagtatctt gctaaaagaa tagatgttta taaaagcgat
      121 aaagaaactt ttacttataa acagtgtagt tctgatttga ccaatttaaa aaaaaaatta
      181 aaatggctta aggaacctga caaattttca ctacaaaacg ccttaaaaga tttagataat
      241 gcatataaaa aattctttaa agaaaaggca ggatttccta aatttaaatc aaagaaaatt
      301 aatagatttt catataaaac taactttaca aatggaaaca ttatgtattg tggtcaatat
      361 ataaaactac ctaaacttgg tatggttaag ataagggata aacaagtacc tcaaggtaga
      421 atacttaatg ctactatatc taaagaacca agtggtagat attatgtatc attatgctgt
      481 actgatgtag atattgaagt atttgaaaat actaataatc atataggttt agatttagga
      541 attaaagaat tttgtatctc aagttgtgga gactttatag aaaatcctaa gtatcttaag
      601 aagtcattaa acaagcttgc taaattacaa agagaattat cgagaaaaac aatcggtagt
      661 ttaaatagaa ataaagcaag attaaaagtt gcaggacttc aagaacatat agctaatcaa
      721 agaaatgatt ttctacaaaa actatctact aaattaataa aagagaatga tattatttgc
      781 atagaagatt tacaagtaaa gaatatgatt agaaatcgta aactatctcg cttaatttca
      841 gatgtatcat ggtcagaatt tattcgtcaa ttagaataca aggctaattg gtatggtaga
      901 aaaattgtaa aggtaggtaa attctttgca agttcacaaa tatgcaataa atgtgggtat
      961 aaaaacgagg aagttaagga tttaaatata agagaatgga tttgtcctag ttgtaatgaa
     1021 actcacgata gagatataaa tgcaagtata aatatattaa aagaaggatt aagactaata
     1081 acgattcaaa ataaataact tatgtaagaa ccgtaggaac tacggggata gcctgtggag
     1141 aattagtaag acatatttta gtatgcaaaa ttctgtgaag caggaaccct gtgactttag
     1201 tcatgggagg ttcagtcaaa ggtatctagt atagttttaa ctcaagacat gatgaataga
     1261 aataatatta gctttaatga tgttgatgga ataacaacat atacaagaga cataaaaggt
     1321 atagaagttg gaattttatt taaagagaaa aaacaaaatg aaattaaagt gagttttagg
     1381 tcaaaaaatt atgttgatgt aagtgaaata gccaagttat ttggtggtgg tggtcatgta
     1441 agggctgctg gatgtactat tagagatagt attgataatg caaagaaaat ggtactagag
     1501 gcagtgttaa aatcaattta aggtgacagt aaaatgaata agattataag tatattgaaa
     1561 cccacaggta tgacatctca tgatgttgta agtagagtga gaaagatttt aaatataaaa
     1621 aaagttggtc atacaggtac tcttgaccca gatgcttcag gtgttttacc aatctgtata
     1681 gggaaagcta caaaagtatg tgaagttatt ttaaacaaag ataaatcgta tatatgtgag
     1741 cttactttag gtataagtac agatacttat gatgcttcag gtgaaatttt aaaaaaagtt
     1801 gatgatttta aatttagtaa tgaagacata gaaagagctt ttgacacaca aagaggagag
     1861 ataaatcaac ttcctccaat ttattcagct ttaaaggtaa atggaaagag aatgtgtgat
     1921 ttagtaagaa gtggtagaca atctgaaatt actttaaaaa caagaagagt aaatataaaa
     1981 gacataaaaa tactaagtat aaaaggtaat aaagtaatgt tttatgttga gtgttctaaa
     2041 gggacttatg tgagaagcat ttgccatgat ataggagaat atctaggttg tggagctcat
     2101 atgtcgtttt tgaatagaac atcttctggt aaatttgact tagataattc aataacatta
     2161 gaagaattag aattatttta tgaaaataaa actttagaca aatacttata tgatatagat
     2221 tatgtccttg attcgtttaa ttatgttgta ttaaacccta atgctataaa atattatagt
     2281 aatggtggct caatagatga taaaaggttt ttaaaaaata atttcgataa agatgatgaa
     2341 tttgtaagag tatacagtac aaataatttc ttaggattag gaaaattatc aaaacacaat
     2401 aatacaataa gtgttaaaag tgataagatg ttcatataac caatgtattt aaaaaaacaa
     2461 caaaagagat agtactataa taacttctat agtctatctc ttttacttat gctataatag
     2521 tttgtgaata agttaagagt aaattatatt ttagcgggga acatttatta tggtgattat
     2581 aaaatctata aaagaaatag caaacataaa agaaagtgtc attaccatag gaaattttga
     2641 tggtgtacac aaaggacatc aagttcttat aggaaaaaca gttgaacatg caaaaaaaga
     2701 aaatatacag agtatcgtat ttacatttgc aaatcatcct gtaaattact ttagaccaaa
     2761 ctcaacaaaa aatattataa gcaatgatga taaaataaaa ttattagaag atttgggaat
     2821 agatatagtt gtaatcatac catttgatga gtatatgact aaaatacctg caaaggattt
     2881 cgtagatgag atactagtaa aaaaattaaa agctaaaaag atagtaattg gacatgactt
     2941 tacatttgca agggcaaaag aaggcaatgt taatctatta aaaagcttag aacatgaatt
     3001 tggttttgag gtagaagtaa taaaacccat caaaatcaat gatgtaagag tgagtagtac
     3061 ttatattaga agtttagtat cccagggtga tatggctaat gtcaaggaat atttgggtag
     3121 aaattacaag ttagaaggtt gtgttataca ttctaaacac cttggaagaa ctataggatt
     3181 cccaacggca aatattgacc ttaagaataa tatgctcgtt ccaaagagag gtatttatgc
     3241 ttctattgta catattggag atgagactta ttttggtgct acaaatgtag gctataaccc
     3301 aacagttaat ggaaaaactt tgtctattga aacaaatatt ttagagtttg atagagatat
     3361 ttatggggaa aatataattg ttgaattttt ggaaagaata agagatgaaa gaaagtttaa
     3421 ttcaatagat gacttaaaaa atcaattgta taatgataca aattatgtgt atgaaaacta
     3481 tgtttgcaaa aacaagtaat gtatgataaa atgattaagg aaaataacca ttactcagca
     3541 tttgaatact ccaatcaatg cttagtaata ggcgtttcta aaaaaatacg gaggtaatct
     3601 aaatgataaa caaatcagaa ataataaaag aatatggaag agctgaaggg gatactggtt
     3661 ctccagaagt acaaatagct ttattaacag ctagaataaa cgagttaaat ggacatttaa
     3721 aaactcataa gaaagaccac cattcaagaa gaggactatt aaaaatggtt ggtagaagaa
     3781 gaaacttatt agcttactta aaggaaaaag atcttgaagg atatagagca ttaatagcta
     3841 aattaggatt aagaaagtaa tttcattctt tataaaaaag caggtatagt gtatacctgc
     3901 ttttttatag ttaattcatt ataaagtaaa atagttaata ataaaagtag tttatatgtt
     3961 ataaaaaatt ataaaatgaa taatattggg taagaatatt aaaatagtat acaaatacat
     4021 aatcaattta aaaggaaaga caggataaat atagaaattt tataacagga taattagttg
     4081 gaataaggag gatattattt tgaaaataaa gttagtatgc gatagtttgt gcgatattcc
     4141 agatgaaata tcagaaaaag attatataga gatagttcca cttacagtta tttttaatga
     4201 tagggaatat atagaaggag tagatataaa gaaagaagag ttttataaaa aagtaaaaga
     4261 aatcaagcaa atacctaaaa cttcacaagc tacatatatg gagtttaaag aagtgtttga
     4321 taagttcata acagaaggtt atcatataat ctgtatgaca ggggctgcaa acgcatcagg
     4381 aacttttcaa agtgctatga tagctaaaaa tgatgtaaat gaaaatgaaa aaatacatat
     4441 atttgatact agaaatttat ctctaggtag tggacaatat gttataaagg catgtgaact
     4501 tcttgaagaa ggactgggat ttgaagaaat tatagatgaa ttagaaaata ctcgcagtag
     4561 tgtaagattg ctttttgcac catatacact tgatttttta aagcagagtg gaagagttcc
     4621 agttgcaact gctttgatag gaaatatgtt aaatataaag cctatatttt tctttgataa
     4681 tggggaagct aagttggtaa ataaggttag aggaataaag aatatagcaa gtaaattggt
     4741 cgatataatt ttagaaatga atgaagggtc tttagaagga aaaatcgtca caataggttg
     4801 tggagataat ttacacgatt gtgaaatatt aaaagatgaa gtaaataaaa gaataaaagc
     4861 aagaagagta ttatttactc gaggaggagt ttctatttgc tctcatacag ggccagatat
     4921 attggctata agttgttcta attagtagta atataaggtt tttgcatata tatgtgaaga
     4981 taattttata ttgttaattt atagtatttt tgataatata gtaaatagag tgatatacgt
     5041 gttttttaat aagaggagga caagcattaa tgtttgaaca taaaatattt aaaatggatt
     5101 ttgcaggaag agaactttct gtagaaatag gaaagatttg tgaaatggct agtggtagtt
     5161 gtatagttcg atacagtgat agtatggtaa tggtaaatac aactaaatca gccaaaccta
     5221 gagacggaat agactttttt cctttaagtg tggattatga agaaaaatta tactctgtag
     5281 gtaagatacc tggaggtttt ttaaagagag aaggcaagcc ttcagagaaa gctatactta
     5341 catcaagatt gatagataga ccaataagac ctttattccc aaaaggattt agaaatgatg
     5401 ttcaggtagt tgcaacagtt ctatcagtag accaagattg tacaccagat atagtagcaa
     5461 tgataggttc ttcaatagcc ctttctatat cagacatacc atttaatgga ccaacaggtt
     5521 cagtatgtgt tggccttgta gatggtgcat ttgttgtaaa tccaaacgca gagcaaagag
     5581 aaaaaagttc aatgcatcta gttgtttcag gtacaaagga agcaataatg atggttgaag
     5641 ccggagctga tgaagttcca gacgaggtaa tgcttgatgc tattttattt gctcaccaag
     5701 aaataaaaaa aatagttgag tttatagaag gtatagttgc agaagttgga aaagaaaaaa
     5761 tgcctgttga attataccat gcaggagaag aaataactca attggttcgc gaatttgcaa
     5821 ctgataagat gaaaaaagca gttcagactt ttgaaaagtt agagagaatg gaaaatatgg
     5881 atagagttaa agaagaaact ttagctcact ttgaagaaac tttagaagat tttgaagatt
     5941 ttgttggaga tatagaagaa gtattacaag atataataaa agaagaagta agaaaactta
     6001 tagtacatga aaatgtaaga ccagataata gaaaacttga agaaataaga cctatatggt
     6061 gtgaaactgg catgatacct agagctcatg gttcagccat atttactaga ggacaaactc
     6121 aagtacttaa tgttgctact ttaggtgctt taggagatgt tcaaaaacta gatgggttag
     6181 atgaagaaga aaacaagaga tatatgcatc attataattt ccctgcatat agtgttggag
     6241 aagctagacc atcaagagga ccaggaagaa gagaaatagg acatggtgct ttagcagaaa
     6301 gagctttatt accagtaata ccatctcaag aagaatttcc ttatgctatt agattagttt
     6361 ctgaagtatt aagttcaaat ggttctacat ctcaagcaag tgtatgtggc tcaacattat
     6421 ctttacttga tgcaggtgta cctataaaag atatggttgc aggtatagca atgggactta
     6481 taaagcatga tggtaaggtt gcagtgcttt cagatataca aggtatggaa gaccatttag
     6541 gcgatatgga ctttaaagta gctggaacag agtatggtat aacagcaata caaatggata
     6601 taaaaattga tggtatagat aaagaaattc tacaacgtgc tttaaaacaa gctaaagagg
     6661 gtagaatcca tatactagga gagatgagaa aaactatatc tcagccaaaa ccagaacttt
     6721 caccatatgc acctaagatt gttaaaatgc aaataaatcc tgacaagata aaagatgtaa
     6781 taggacctgg tggaaagata ataactaaga taatagacga aactggagtt aagatagata
     6841 ttgaacaaac tggggaagta tttatatcag gtattgagat tgatatgatt aagaaagctc
     6901 aagaacttat aaataatata gtagttgaac cagaagtagg aaaaacttat aaaggtaagg
     6961 taagtagaat aatgaacttt ggagcatttg ttgagatact tccaggaaaa gaaggattac
     7021 ttcatatatc tcatatagct catgaaagag ttgccaaagt tgaagatgta ttgaatatag
     7081 gggatgaagt tgaagttaaa gttacagaga ttgatgaaaa aggaagagtt aatttatcaa
     7141 gaaaagttct tttaccaaaa ccagaacata aaaataaata acttattata taattaaaag
     7201 caaagtctta ggattttgct tttttaaata caaaaaagta gataatttta aaatgatagt
     7261 tatggatggc ttatagttct ttttctgtca ggctttactc ttataaagaa gctatttaaa
     7321 agctgattaa tagagagctt tattgatata tatagaatca cttaagttat atttagtgca
     7381 taaacagagc ttatttttaa tagtattaaa taagaaacaa tttgtacata attaggggga
     7441 gttttaatga taatgatggt acttaataag agtaagctca aaaaaatcat aatactaatt
     7501 ttagtagtgt tattagtatt atcaggaggg gtaatggtat taaagttatt taacaacaag
     7561 ccagtattta atttatttaa tggtgtagat ttaccatatg aaagaggtac aaaggataaa
     7621 agtggatatg ttgcattaac ctgtaatata gaccttggat gggaaacaga gtacgtagaa
     7681 tccattttag aaacacttaa aaaagaaaat gtaaagatta catttaatgt aactggaaaa
     7741 tgggcagaaa agaataagga tgaattatta aagataaaaa aacaaggaca tgaaataggt
     7801 aatcatggat acaaacattt agattattct acattatcat atgaagacaa ttatgagcaa
     7861 atagagacct ctaaaaagat aattgaagaa attataggtg aaaaaactaa attttttcaa
     7921 gcaccagcag gttcttttgg tccagaaaca gtaaaggctg ctaaagcatt agggtatact
     7981 tctatcaaat gggatgccga tactatagat tggaaataca aagaccaacc agaggtaatc
     8041 attgatagaa tgaagaaaaa agacattaaa gatagtagta taattttaat gcatccaacc
     8101 aacgcaacga caaaatgtat agatgatatt atagctattg taagagaaaa aggactaaaa
     8161 ccaggaaaac ttagtgatgt atttaagtag acaaagtata aatatttggt taagattgta
     8221 taagttgtag ttgaattaat taaaagactg acttataatg taatacatat aaaaaataaa
     8281 tataattaaa acatagtgtt ttcaataatc caatatgaaa caaagaataa attgttagga
     8341 gaatgtaatg tataagacaa aaatactgga aaatgggctt acaataattg gtgaagaaat
     8401 accatatcta aagtcaataa cattaggtat ttggataaat gcaggctcta ggatagaaga
     8461 agcacaggtg agtggaattt ctcattttat agagcatatg atgtttaaag gaaccaaaaa
     8521 cagaacatca aaagagattg ctagttcaat agataatttg ggtggtcaaa taaatgcatt
     8581 tacaagtaaa gaatgtacat gttattatgt aaaactaata gatgagcata tagatacagg
     8641 aattgatgta ttgagtgata tgatactaaa ttctaaattt gataaaaatg atatagataa
     8701 ggaaagactt ataatattgg aagaacttaa gatgtatgaa gactctccag atgacttatc
     8761 ttatgattta ttagtggaaa atatatatgc taatgatgga ttaggaatga atataattgg
     8821 gacaaaagaa tctctataca atataactag agaatccatg ttagaatact taaataagta
     8881 ttatattcca aataacgctg ttatttctat agctggaaac tttaactttg atgatatggt
     8941 ggagaaaatc aaatcaaaat ttggacactg ggaaaagaaa aatttaagta tagacataag
     9001 tgaggctaag tttaatcctt gctttatatc aaaaaataaa gatactgaac aggtgaactt
     9061 agctatgtgc ctaaaaggta ttccttttga aaatgatgaa gaagtctatt caatggcagt
     9121 ggtaaataat attttcggtg gaagtataag ctcaaggctt tttcagaaaa taagggaaga
     9181 aaaaggttta gtatattcaa tatactcatc acagacatta tataggaaat gtggtgaatt
     9241 aggtatattt gcaagcatga gtacagaaaa tttacaagat gtatataatt taataaagaa
     9301 agaaattgaa aatataagag aaaactatct tacagaaaaa gaaatatctg aaagcaagga
     9361 acagttaaaa ggaaattata tattggattt agaaagtact agcagtagaa tgatgtctac
     9421 tggtaaatct atgttactta gtaaaaaagt aaaaactaca gatgaaatac ttgaatgtat
     9481 aaataatgtt aatattaatt caataaagaa ggttgttgat aaggtattca atatcgaaaa
     9541 tattggtaca tgtatagttg gaagagatgt agaaaagatt ctacacttgg attaatattg
     9601 aaaaaagtaa atctctggag gtataaaata tgaatttatc tgaaatagca ggtaaggaaa
     9661 tagttaactt ggtcacagga gaaagattgg gggtcattgg agaatgtgac cttatactag
     9721 atgaaactac aggcggtata ttagcgcttc taattccaaa agaaaaagga ttttttgcca
     9781 gaagaaaaga taagtcattt ttagaagtac catggagaaa tgtaaaaaaa ataggtaatg
     9841 acatgataat tatagaatat gagggatata tttaggagga aaaaatgagt attttagtgc
     9901 aaaagtttgg tgggacatca gtagaatcat atgaaaaaat gaatgaagta tgtaagatag
     9961 taaaagcata caaaaaaaat gatgaagaat tacaattagt attagtagtt tcagcaatgg
    10021 gaagaaaagg agctccatat gctacagata cacttataaa tttgtgtagt gcagtaaatg
    10081 atgagccaag taaaagagaa cttgatttaa taatgtcttg tggagaaata atatcaggaa
    10141 caattcttgc taatttattg aatgcacagg ggatagattc tgttttcttt actggtcagc
    10201 aagcaggtat aattacaagt gatgaatatt ctaatgcaaa gataaagtat ataaatccta
    10261 aaaaggtaaa aagagcttta gatgatggta aggttgtagt tatagctggg ttccagggtg
    10321 taacagatga tggagaaata actactcttg gaagaggcgg aagcgataca tcagcagttg
    10381 ctattggtaa agctttagaa tgtgaaacag ttgaaattta cactgatgtg gatggtataa
    10441 tgactgcaga ccctagagta gaaccaaacg ctaaagtatt gagttttata gactatgagg
    10501 aagtattcca aatggctgac aaaggtgcaa aagtaataca tccaagagca gtacagttgg
    10561 ctaaaagtgg aaatataact ttagccataa agaatacaat gaatccaact tttgaaggta
    10621 caaaaatagg ttctttatgt agacacttag aagacaatat agaatatgaa caagaaagag
    10681 attttaaggt tgctgttgca aataaagata gcgtagcaca agttaagatt aagtcagcag
    10741 aagaagtgtt tacagaagta ttaaatgaga tagaaaagaa acttataact atagatatga
    10801 taaatttctt tatatcagaa aaagcatttg ttgtagaaga tgctgatata aaatcattaa
    10861 aggaaatact agataaattt gaattagatt atgaagtaaa tagagactgt gctaaagtaa
    10921 cattgatatg ttcaagaatt gctgatgaaa tgtctggtat catgtcaaag gtagttagag
    10981 gattatcaaa agcaggggta tctcttttac aaacatcaga ctcaaatatg actatatctt
    11041 gtttagttag tgaagaagat atgcatacag cagtacatgc tatacaccaa caattttatt
    11101 taaaataaac tgtataatac aattattttt taatcaaatt taagaatttc atatatatct
    11161 taatatattt gatttatttg gtaaaactaa attaaatata attttgatag gagttttttt
    11221 atgaaagatt atagagaaga taatgaaaga tttgataaag ataattgtag tgaagaatct
    11281 agttgcgaag agagagaatg tataaagcaa tttggtacca atgaaatgcc acctcaacct
    11341 cctaaagata ttcaatgtat aactataatt ggagaaattg agggacattt tataggaaat
    11401 cctcaaaaaa aagctacaaa gtacgagcat ataattccaa tgctatactc aattgaggaa
    11461 agcaatgatg ttaaaggagt gttagttgtt ttaaacactg ttggaggaga tattgaagca
    11521 ggtttagcta ttgcagaact tttaaacagt acatctaaaa aagtagttac tcttgttcta
    11581 ggaggaagtc atagtatagg tgtccctctt gctacagcag gagattactc atttatagca
    11641 ccaacagcaa ccatgattat acatccagtg cgaactactg gtcttgtgat tggtataaat
    11701 gagacttttg agtattttaa aaagatgcaa gatagaataa ttcaatttat aataagaaca
    11761 tcaaatatca aaaaagatgt acttgaaaaa cttatgcatg aaaaagatga acttgtaagt
    11821 gatgttggta gtgtattaat aggaaaagaa gctgtggatt atggtcttat agatgaagtt
    11881 ggaggactaa aagaagcact taaaaaatta agagagctta taaaagaatc tgaggaagaa
    11941 aaaaataatg attaaaattt gtttaaataa taaaatttat gatataatga tgtaataaag
    12001 taggagtgtt agtgttaagg cattagcact ttttgctgtg aaggggtaaa acttgctaaa
    12061 aataaggagt gatattaatg gccacgaaaa agaagaaaaa aaagaaggta aataccttaa
    12121 gttttaatgc agaatatcat aatttaataa caatatttat aggtgtattt ttattatata
    12181 gtttaaattc taattctatg ggatggatac ctgtgttaat gcaaaatctt tttaagggac
    12241 tatttggagg gctttcaata gcaataccat ttatagtaat tataacagga cttttaggat
    12301 tttttgatgg aaatgaatat atatataggc taagaaagac taaactatac tacataatta
    12361 ttttatttat atttgtattt tatggattat taaatgcagg aactcttcct gtagatagcc
    12421 cactaaaagg taacatgttt gatgatgtta tgaaattggg tgtaagtgga caaggtagtg
    12481 gtttgatagc aacaactatt gcgtattata tgagtaaaat atttggtata gcaggtggat
    12541 ggttaataag tatcttcgca cttatacttt ctgtaatgtt tatatttaat atttctataa
    12601 aagatttggt gtcaaatgca aaatcaaaat ctaaagcatc taaagacagt aatttaacgt
    12661 ttaaagataa aattgcaaat atgaaaaaat ctgcaataga tatgatgact gatgaagtag
    12721 atgatactac tataaataaa aaaccaggtt tctttaaagg gttaatgtca aaaggtctta
    12781 ataatgatga tgaagaagat gaatattttg aagaagaaaa tagtgatggt gtagatgata
    12841 aaactataaa aatagttgga tttaataagg cagaagatga gtatttagaa atattagaag
    12901 gaactcaaag tatgccagag ctagatgttt taaaagaatt acaaaaagct accaatgaaa
    12961 atccagttgt agatactaaa ccagaaaaaa aagttgatat agctaaacct aatttaaata
    13021 tagaaaaaac tcaacctatg agtattgtag cagagccagt taatgaggat tattcaaact
    13081 ataaaaagcc tagcattgag cttttaaata aagtaaataa gaagtctgat gaaaatggta
    13141 aaaagaaagt gttgaaaaat gcttctcttt tagaaaagac actatcagat tttggagtgg
    13201 aagcaaaaat taatcaagtt acagttggac ctactataac aagatatgaa atacaaccaa
    13261 gtccaggagt caaggtaagt aaaattgtaa atttaactga tgatatagct ttaagtttag
    13321 cagctaaaag tataagaatt gaagccccaa ttcctggtaa aagtgcaatt ggaatagaag
    13381 ttccaaatga agaagctcaa atggttggtg tgagagaagt tctagaaagt gaagaattta
    13441 ataattttaa ctctcctctt gcaatgggac ttggaaaaga cgtagcagga aaaattataa
    13501 ttggagatat aggtaagatg ccacacttac taatagctgg ttctacaggt tcaggaaaga
    13561 gtgtttgtgt aaatacatta ataagtagta ttttatataa ggcaaatcct gatgaagtaa
    13621 aattactatt aatagaccca aaagtagttg aacttgcaaa ttataatgga ataccacatc
    13681 tattgatacc agtagttact gaccctaaaa aagctgcaaa tgctttaaat tgggcagtta
    13741 cagagatgaa tagaaggtac aaattatttg cagatgctca agtaaaagat gtaacaagtt
    13801 ataatgagaa agcggaagaa aaacttccta aaatagtaat aataatagat gagttagcag
    13861 atttaatgat ggcaagtgca aatgatgtag aagattatat ttgtagatta gctcaaatgg
    13921 caagagctgc tggaatgcac ttgattgtag caactcaaag accatctgtt gacgttataa
    13981 caggggtaat aaaggctaat ataccatcta gaatagcatt tgcagtatca tctcaaactg
    14041 attcaagaac aatccttgat atgggtggtg cagagaagct tctaggtaaa ggtgatatgt
    14101 tattctatcc acttggtgca gcaaaaccag ttagacttca aggggcattc atatcagaga
    14161 gtgagtcgga aaaagtaatc gattttgtaa aaagtcaggt taaagatgga ataaaatatg
    14221 aagaagatat aattgaaact atatctaagg ttaatacttc aaagggtagt gatgaggatg
    14281 agtttttgag tgaagcgata gaatttgtcg tggaaagtgg tcaagcatct gcctctatgc
    14341 tacagagaag atttaaaata ggattcaata gagcagctag acttatagat tctatggaag
    14401 aaagaggaat aattggagca agtgagggaa gtaaaccgag aaaggtatta ataagcaaac
    14461 aggatttgca gaatttagaa ggtgaataga attgtcagtt ataaaaatag aaaaagcact
    14521 taagctagat aaagtaatat ttgtagatgt gagaactgaa ggagaatatg aagaagacca
    14581 tatattgaat gcaatcaata tgcctctttt taaaaataat gaacataatg aagttggaac
    14641 aatttataag atgcagggaa aacatgaagc aatacaaaaa gggtttgact atgtatcgta
    14701 taaattaaag gatatatatt tacaatctgc agaacttgca ttaaattatg ataatattgt
    14761 catatattgt gcaagaggcg gaatgagaag tggaagtata gtaaatttat tatcatcatt
    14821 aggtgtaaat gtatatcaac ttgaaggtgg atataaggct tatagaaatt ttgttttaga
    14881 gtatttaagg catgtaatgg atacaaaaaa ctttgtatct gttcatggat tgactggtac
    14941 aggaaagact gatttgttac atttattaga tgaaaaagga atagacgtac tggatttaga
    15001 aggcatagct aaaaacagtg gttctacctt tggttttata acttttgata aaaagccacc
    15061 atctcaaaag aactttgaaa caaaactatt tgaaagtata tttttttcga aagagaatta
    15121 tatatttgtc gagagtgaaa gcaaacgagt tggaagtgtt acagttccaa atgaaatttt
    15181 cgaggcaatg acacgagaag gacatcatat attattagaa tgtgatattg aaaatagagt
    15241 cgatagactt tgtagagatt atatttatga taaagatgaa ggtaatatat tgattttaaa
    15301 agaatgtata aacaagttta gaaaaagatt gggtaataaa gtagtagatg attatattga
    15361 tttattagaa tcaggtgaat ataaagaact tgtaaaaaga tatcttttag aatactacga
    15421 cccactttat atgcattcag tagagaaata taagtatagt aagattataa attttaatga
    15481 tacacaaaaa gctttagaag atgttataga cttatatgag agtatattgg aaggagaaag
    15541 tgaatgttaa aaatagcatt ggaatcatta ggatgctcaa aaaatttagt agatgcagaa
    15601 ataatgatgg gaattttaaa taacaaaggc tataaattaa ttggagattt tgaagaagct
    15661 gatgtaatta tagtaaatac atgtgggttt atagagtcag ctaaacaaga atctatagat
    15721 acgataataa actttgcaga gttaaaaaaa actggcaatt taaagttgtt gatagtaaca
    15781 gggtgtctag cccaaagata ttctgaagaa ttaaaaactg aaattcctga aatagatgct
    15841 atagtaggaa caggaagcta tcaaaatata gataaaatac ttaaagaatt aagtgaaatg
    15901 catcaaattg taagccttaa tgatatagag tttgtattta atgaagattt accaagatat
    15961 atatctacac ctagctatat ggcctattta aaaattggag aaggatgctc caataattgt
    16021 acttattgta taataccaaa actaagaggt aaatatagaa gtagaaaatt tgaagatata
    16081 attaaagaag ctaagaaatt agctgaatct ggagtaaaag aacttgtggt tatagcacag
    16141 gatacgacaa agtatggttt tgatttatat ggaaaagaaa gattatcaga acttttagaa
    16201 gaacttgcaa aaatagatgg atttaagtgg ataagggtta tgtattcata tccagaatct
    16261 ataacagaag aattgataca agttataaag aaatacgata atatatgtag ttactttgat
    16321 atgccaatac agcatgcaag taacaatatt ttaaaattaa tgaatagaaa aactactaaa
    16381 gaagatatat taaataaaat caatctgata agaagtaata taccagatgc tatacttaga
    16441 actacaataa tagtagggtt tcctggtgaa acagaagatg acttcaaaca acttgtggac
    16501 tttgttgaag aggttaaatt tgatagactt ggtgcatttg catattcaag agaagaagat
    16561 acaccagcag atagattgcc aaaccatata gatgaagaag taaaaataca aagaagagat
    16621 actttaatga tgattcaaca aaaaatatct gaagaactta atgacaaaaa gataggaaaa
    16681 acttatgagg tgttaataga agaacagata gaagataatg tatatacagg aagaacacaa
    16741 ggtgatgcag aagaaattga cagtatagtg tatgtaaaaa gtgtagacaa tcttgaagta
    16801 ggagaatttg taagtgttca aataaatgat gcaatggaat acgatttaat gggagatgtt
    16861 ttatatgaac ttgcctaaca agttaacttt gtttagaata tttttaatac cagtatttgt
    16921 tttaattatg ttgctcaatg taccaaataa atttttaata gcttgtatta tttttataat
    16981 agcttcaatt actgatgctt tagatggaaa aatagctaga aaatacaatc tagtcactga
    17041 ctttggaaaa tttatggacc cattagcaga taagttattg gttatttcag cacttacatg
    17101 tatgatagaa gaccatcttg taagtagttg gatggtaatt ataatagtgg ctagagagct
    17161 tacagttagc atattaagag ctatagctgc tgctgatgga aaagtaattg ctgctggaaa
    17221 cagtggaaaa cttaaaacga taactcaaat ggtatctata gtgtttttat tgttaggtgc
    17281 tcagtttgaa aatgtattga tattaaatat tggtgaaatt ctcattctta tagctacact
    17341 acttacatta tattctggat gggaatatct atataaaaat aaagagcttt ttatgtcttc
    17401 taagtaaaaa attatgcttt aataaataaa aactaatgat taataaataa aaaataacaa
    17461 cttaaaattt taaaaatgta aaaaagggta tactattata gtatacctct tttcatttta
    17521 agaatatttt cttttgtgta tataattatt aataatggtt tataaataaa atgtaatgaa
    17581 taaaaatata atcattagta gcgtttttaa attgactagg tttgatttat gttatataat
    17641 taatatataa caagagaaca aatgtttgta gataaatgaa gggatggtat agagatgagt
    17701 gtagatcaag aaaaattaaa agcgttgaat gaagctttag gtaaaattga aaaagatttt
    17761 ggtaaaggtt cagtaatgaa attgggagaa gcaacatcta tgtctataga tgttatatca
    17821 acaggagcga ttggtttaga catagctatt ggtataggag gtctacctag agggagaata
    17881 gttgaagtat atggtccaga atcttctggt aagactactg ttgcgcttag ttgtgtagca
    17941 tcagctcaaa aagatggagg aatagctgca tttatagatg cagaacatgc acttgaccca
    18001 gtatatgcaa aagctttggg tgtggatgtt gataacctaa taatatctca accagataca
    18061 ggtgaacagg ctttagagat agcagaggca ttgataagaa gtggagcgat agatataata
    18121 gtaatagact cagtagcagc attagttcca aaggctgaaa tagatggaga tatgggtgat
    18181 tctcatgtag gtttacaagc tagacttatg tcacaagcac ttagaaagtt aactggttca
    18241 attaaaaaat caaattgtgt tgctatattt ataaaccagt taagagagaa agtaggaata
    18301 atgtttggaa acccagaaac tactactgga ggacgtgcac taaaattcta ttcatcagtt
    18361 agattggatg ttagaaaaat agatacaata aaacaaggtg ataaagttat aggtagtaga
    18421 actagagtta aagttgttaa aaacaaagta gcaccaccat ttaagcaagc tgaatttgat
    18481 ataatgtatg gagaagggat ttcaaaaatt ggagaccttt tagatatagc tgctgatgta
    18541 gatatagtta aaaaatcagg ttcatggtat agttacaatg atactaaact tggacaagga
    18601 agagaaaatg ttaaaaaatt cttggaagat aatttagatt taactactga aatagatgag
    18661 aaagttagag cattttacaa tttaaatgaa gaacatgaag aatcaggtac ttcagtatca
    18721 aaagaaattg tagaagaata agtaaaaata caaaaaaata actagtaatt aaagacatgc
    18781 cacgctccct attagcttga cacaatgttg aaaaaattat aaaattaagt gaggataaaa
    18841 tatctaaatt taattttaat tattaggaat attttttaat catagtgatg acattttggg
    18901 attattaacg aaggaggtgg atgtcataga tagtgtagta atgattgtaa taggtgcagc
    18961 tgttggtatt atagctggat attttattag aaaaaatata tctgaagcaa aaattggaca
    19021 agctgaaaac ttggccaaag aaataataga taaagcacac cacgactcag aaacagtaca
    19081 aaaagaaaaa ttactagaag ctaaagaaga gatccataag tggagaacag aagctgaaag
    19141 agaaaacaga gaaagaagaa cagaagtaca aaagtatgaa aaaagagtag tacaaaaaga
    19201 agaagtctta gatagaaaat tacaaaattt agaatctaaa gaagtaaacc taagtgaaaa
    19261 attaaaggta gtggaaaaga aagaagaaga agttgaagta ataaaaactc aacagttaga
    19321 aaaattagaa agtatatcag gaattacttc tgataaggcc aaagaaatca tcttaaccaa
    19381 tgcggagaga gatgtaagac gtgaaatgtc tataatgata aaagagatag aaagtcaagc
    19441 taaagaagaa gctgataaga aatcaagaga aattatagga tatgcaattc aaaaatgtgc
    19501 agcagatcac gtagccgaaa ctactgtaac agtagtaagc ttgcctaatg atgaaatgaa
    19561 aggtagaata ataggtaggg aaggtagaaa tataaggact ttagaaacct taacaggtat
    19621 agaccttata atagatgaca ctccagaagc cgtaatttta tcaggatttg atccaataag
    19681 aagagaaatt gcaagaattg ctctagaaaa attaatagca gatggaagaa tacatccagc
    19741 tagaattgaa gaaatggttg aaaaggcgag aaaagaagtt gacaatatta taaaagaata
    19801 tggtgaacaa gctgcatttg aaactagtgt acatgggatt catccggaat taataagatt
    19861 attaggtaga cttaactata gaactagtta tggacaaaat gtacttaaac attctataga
    19921 agttgctcat atagctggta taatggctgc tgaaatagga gcagatatta gattggctaa
    19981 gagggcaggt ttattacatg atataggtaa ggctgtagac catgaaatgg aaggtacaca
    20041 tgttgaaata ggtatggatt tacttagacg ttataaagag tctaaagaag ttatacatgc
    20101 catgagtact catcatggag attacgagcc tcaaacagta gaggctgtat tagttacagc
    20161 agcagatgca atatcagctg ctagacctgg tgcgagaaga gaaactttag aagcatatat
    20221 aaagagactt gaaaaattag aagaaatagc taattcatat gaaggtgtag aaaaatcatt
    20281 tgctatacaa gctggtagag aaataagaat aatggtaaaa ccagaagcta taaatgatga
    20341 agaaatacat ctattggcta gagatatgac taagaaaata gaggatgaac ttgaatatcc
    20401 tggacaaata aaagtaagca taataagaga aacaagagct atagagtatg cgaagtaaaa
    20461 gaaataatat ctaaataata agaaaatatt tttagaaatt taaatttgcc acaagatatg
    20521 ataatatatc ttgtggcttt taaattgttt aagtttaatt ttatataatg caaaaataat
    20581 ctaagtgcta aaagtgctac ttacaaaaga ttaataaaat aaagctttat atatgtatta
    20641 tttatataat tatccaagtt tgtttgatat aatgaagttg taaaataaat atattactac
    20701 ttggaatgct tgtacttaaa taagatgaaa atacaatgac gctaaagtga ggattagaga
    20761 gagggtacac tatgaaaaaa aatacacttt tacatacaaa tattatggtt tgcattatta
    20821 ttactcttgg ttttgtggct acctctataa ttggatatca atctaatacc aatattttta
    20881 aaaatgatat tgaacatgta tctacattgg ctgctgaagg tatttattat cagatagata
    20941 aactactttc agaacctata aatgtatctc ttacaatggc aaatgacagt ctattaaaaa
    21001 attttttaga tggtgagaaa gaacatttaa atgatgaaga atttatttat aaattacaag
    21061 attatctgaa tgtgtataga aataaatatt catatgattc tgttttttta gtatcaacta
    21121 aaaccaataa ttattatcat tttaatggac ttgatagaaa tcttagcgct aataactcag
    21181 agaatcaatg gtattatact ttcttaaaga atgatgatga atactcatta aatgttgata
    21241 atgatgaagc aagtaacaat agtattacag tctttgtaaa ttgtaagata aaagatgata
    21301 atggagcaac tatgggaatt ataggtgttg ggttaaaggt taattcatta caaatgttgc
    21361 ttaaaggata taatgacaaa tttgatgttg ttgcacgctt aattgatgat aaagggtttg
    21421 tacaattagc agtagataaa accggtcatg agaatataaa tttttttgaa aattctagta
    21481 gcgacttgtc taattcgaaa caattaatat taaacaacaa aaaggaacaa aagagttttt
    21541 ggtattcatc tgaaaaatca aaaagttata ttgtatgtca gtacatacct agtttaaaat
    21601 ggcatcttgt tctagaaaat gattttactt taatgattaa acagcttcat ctgcaatttt
    21661 ttaaaggcat tgcagttata gttttaatta taatatttgt actttttact attacacatg
    21721 tgcttaaaaa atacaaaaac caaataataa agcttagtgt ttcacagaaa ttggaatatc
    21781 aaaaattgtt gagcaaatct actgaaggtc tttatgaaaa tatttttgaa attgatatta
    21841 ctaacaataa agctggttgt gaagatgaga ataggtattt tcatgaattt ggattagggc
    21901 ttaatacccc atatgatgaa gccttacata caatagctaa aaaccaaatc aaagaagaat
    21961 atgcacaagg ttatttagat acatttttac ctgaaaatgt aattaaacgt tataatagcg
    22021 gaattaataa tatcagctat gattttttaa ttaaaaaaga tgaagaaagt tatcattgga
    22081 ttagaattaa tgcacgaatt ttcttttgga catcagatga atctgttcgt atgatatctt
    22141 atcgtaaaaa tatagataaa gaaaaaaata gagaattact acttctcgaa cgttcacaac
    22201 gtgattctct tacagggctt tacaataaag ctacaacaga ggaatttatt cgttcatttt
    22261 taaaaaatga aagtaatcaa gatttagaac acgtttttct aattttcgat attgataatt
    22321 ttaaaaatgt aaatgataaa tatggtcatg tatttggaga ctttgttata agtgaatttg
    22381 ccttagaatt aaaatctcaa tttcgtgagg acgatattgt gggacgtatt ggtggagatg
    22441 agtttgtagt attaataaaa gactttaata ataataacta tgtgcttata gacaaattag
    22501 agcgtttttg ttctaagatt aatcagaaaa aatttgttga gcaagcagaa ttttctattg
    22561 catgtagtat tggtgtagca atgtatcctg aacatggata tgtatactct gaactatatg
    22621 agaaagcaga ccaagcactt tactatgcaa aaagccatgg gaaaaattct tatcatatat
    22681 tttcagagga ttctattgat agtatttcat ttcatataga ctctagagat ataaaagtat
    22741 tattagaaat ggctactgat ggtgttgtca aatttgcttg tatggaaaac ttaaaattac
    22801 tttatttcaa ccaaaaaatg cttgaattta ctggatattc agctcaaact gttacttcta
    22861 taggttttga tattttttcg cctgtattac aagacgactt acaaatggta ctagatacat
    22921 taagagaagc aatttctaaa agagagactt ttgaaatagt ttttcgtttt tgtcatacag
    22981 atggtcatat ttttcctgta aggatgcaag gtaagtttgt aagtgaatta tatcaaaatc
    23041 gttatcctgt tttttatgcg atttatacag acatatcaag tatcaatact ttactagaaa
    23101 ataaatagta aatactacag taaaatctaa aaataggata taatagtatt aatataagaa
    23161 gattataaat aaaacctgct aatgaaaata gattattttt agcaggtttt taaatttttt
    23221 ataataaatc ttatttttgg ctaacaagat ttattttttt taaaacttta cttattattt
    23281 taaaaattaa ttatgaaatt tatcgtttta ttatttacag aaagtattct ataacaataa
    23341 atatctatat ttattgcaaa attattttag cagttttgta tttatttgta tttattttga
    23401 atttatttac taaatttgcc tataaaaagt atatataaaa atatagttca aaatggtata
    23461 attaagtata acagaaggag gtaatgtaag tgagccaata cataaatata aattctcagt
    23521 tagacgccct aaaattgaag gagttcgaga aaatatttta cgaaaatatc aatgaggacg
    23581 ttaaagtagt gccaaaagtt actcctttta aaggaataaa taccgatttg ttgtatgtta
    23641 aagatggaag aattttattt ataaaattta tggatacaac agaagatata ttttttattt
    23701 tagaagaaga gttacttgaa gttatgaatg aggaatatga acttttgaaa ctaaaaatgg
    23761 gacaaaagaa tagaaatata agttataact acgtttacat tatgccatac gttgaagttg
    23821 aggaaacata tgaatttgaa gaatttgtta ataataatat aatagataaa aataagcttc
    23881 aagatataat gaataagggt tcgctggagg aatatcttaa tgatgagaat gatgaaataa
    23941 acttaaattt atttttacta gatatatgtt cagaatacta tataataaat gataaacttc
    24001 atctaaatga aaaatttaaa aaaatttcat tctacaatga tgactataag tatacagcaa
    24061 ctatgatgga agacgttcaa attaaagatg ttgtttctat taaatatggg aatacactta
    24121 ttgaaggtgg ttctggtata ggcaaaacag caattatgct ttctagggct ataaaattag
    24181 caaaagtata tccacatcat aaattagtca tatttacaca tacaaaacaa ttgtgcaatg
    24241 agcttcgaga aaggatagag ttattataca aagataataa caatttagaa gttcacacat
    24301 ttagttcttt tatatttaaa ctagctaaaa aattcaattt aattgtagat tataatatgt
    24361 taaaaaatga ttacgaaaag acctttaata atcttgtaaa acaagcacag aacattataa
    24421 aaaataaaaa tatgttcaag gctattttta ttgatgaagc agaaagcttt ttagagtatg
    24481 aaatagattt tataagggag tttttatata aaacaaaatt catatttaat gtatgttctt
    24541 gtaactcctt gaatatctct aatagattga atatatttaa aaaattatat aatggtatag
    24601 aatttgatga taagattatc ttaagtaaaa attatagaca agctaaagag attgtagatt
    24661 ttacaaataa attttcaaat aattctaact catatataaa cgaattaaga ccaaatacag
    24721 aatttagtac tttcttttat actaaagcac ttagaggtgg aaataagtct gttgatataa
    24781 taaaagtaag tgaccttgat gaccaaataa gttctgtaat ctgggaaatt gagtatttaa
    24841 taagtaaaaa aggtcttgat tattctgaag ttgctatcgt ttacccttac aataagaaga
    24901 aattaaaaag tggaaaaacc atttactttc aatatatgtt aaaaaaagca ttggaagagg
    24961 caaaaattcc ttatatatgt gcagaagata atttgacaaa tataagtaag aaggtaggaa
    25021 ctacaatagc aaatatatat gcaataaaga atttagagta taaagcggta atagtatgtg
    25081 aattagagat gttatataat caaactataa atgatattga acaagattat caagtaaatg
    25141 actttgtagg agatttaaat aaggtttatt tagctatgag tagagcaaca gactacctaa
    25201 gtatagtaac aacttttaat gaagaagcaa gtgatataat aagacttatt acagaatcaa
    25261 aagatattta gtaaaaaaat atttgtaatt taagaaaata aaaagagact gagatttgta
    25321 aaataaactt taccaattca gtctcttatt ttttagtcta ctttcccaat attatcaaga
    25381 ggtaatagtc tcaccataac cttaccaaga acttcatttt catcaaccat acctacatca
    25441 gggaatctac tatcattact attttctcta ttatctccca ttgcaaatag tttacctttt
    25501 ggaacaacag tatctatatc tccagaagta tagttattgt gtatatatgg ttcatttaat
    25561 aattttccat ttacatacac tttagaattt gatattttta ttctgtcacc ttcagtagct
    25621 ataactcttt ttattaagtc ttttttcttt cctgtttctc catcaactaa attggtttta
    25681 aaaactacaa tatcgccttt ttcaggttta ccaaccttgt atgatatcct atttaaaatc
    25741 agataatctt tatcatctaa agtaggatac attgattctc cacttacaat agaaggtctt
    25801 ataaattgta gaattacaaa tgcaagtaca atagccatag ctattgactt aatccaatca
    25861 aatatttctt ttttaacact cataactttt ctccttatca tttgttatta aattagaata
    25921 cattataata gaaagaaata agcaagaacc actataccca agactattct ataataacca
    25981 aatactttga agtcatgttt tttgatatag tccataaaaa atttaataac tacaattgaa
    26041 acaacaaatg ctactacaga accaacacct aaaataagcc attcaaatcc agtaaatcca
    26101 aatccagctt ttagaagttt taatgcacta gctccaagca ttgtagggat ggctaagaag
    26161 aatgaaaact ctgctgctac atatctagaa gtaccaagta atactgcacc tattatagta
    26221 gaaccagacc tagatgtacc tggtataaga gctagacact ggaataatcc tatacaaaga
    26281 gctaatttat atgtaacttg agaaaaatct ttatacttag gtcttttatt tctcttttca
    26341 agccctatca ttattatacc atatacaata agagcaatag caactactgt tgaattaaag
    26401 aataatctat ctatatcatc ttcaaatagt attccaataa ctccagatgg tataactgca
    26461 attataacct taagccataa acggactgtt tcttttttct gcttaatatt ctttgcgcta
    26521 tcaaaaggat ttaattttct aaaaaatata acaagtacag ctaatattga accaaattga
    26581 attacaacta aaaatgtact tataaatgta tttgaaaaat tcaattttat aaactcatca
    26641 actaatatca tatgccctgt actacttact ggtagccatt ctgttattcc ctgaactatg
    26701 cccaaaatga ctgccttaaa aatttcaagc aaactaaatg tttccaaatc aaaatacctc
    26761 caatacaaat ttatagtagc atattttatt catagattaa taaaaaaatg ccacctttta
    26821 ctaacttata ataccatagt actgtgtagt gcacaatgga agattgatat tttcataaaa
    26881 ccttcataat ataacaaaat aaacttaaaa gttatctatt gaataagggg tatatttgag
    26941 ggggaaatat atggtatagt aaaagtatag ctattttatt ttatgaaaag gaaaggagtt
    27001 attatgtata gtacaaaaat actagatgat tatgagtatg aaacttttaa tgttttttct
    27061 acaaaattaa atccaaacac gaaacacgat tatttatcaa aggttatatt gtttaaagaa
    27121 tttttaaaag ggaaagaatt gatttatgct acgaaagaag attgtaaaaa ttttgtagac
    27181 tatatacaga ctaaatatgc gaaatcaact tgtgaaaaga tatatagtta tttacatagt
    27241 ttttataact tcttaaaaaa agaaggatac atagatataa atccatttag atatgtagaa
    27301 aaaccgacag taacaagaat aaaaacaaaa gatgatgttc taagtataca agaaataaat
    27361 aaacttatag gtatcctacc aaaattaaat ataagagata gagtaataat agtctgtcta
    27421 gttactactg ggtgtttatt aaatgaatta gttagcttaa agtggaaaga ccttatggta
    27481 gatgaaaacg ataactcata tgtaaggtta ggtaagggaa gaaaagaaag agtagttaaa
    27541 ttacatccat acttttttaa acttttagaa gattacagga attattctgg gcttccagag
    27601 gtaataatac ctagtgatga ttttattttt acaactcaaa agagtaattc tataacagat
    27661 agaaatgtca gacttatagt caaaaaagca ttagatttag ctggactttc tcaatattca
    27721 gcaagagatt ttagacattc atttgcagca ataagtttaa ggcttggggc agatgaaagt
    27781 gatgtaaaaa atcagcttgg atggagtgat aaatactatg caattagata taagtatgta
    27841 ttaaattttg ttgatagtga aatagtggat tacttaattg aaaaagataa tttggatata
    27901 aataaaaaat agtaataaat aaaaaatact atatataaat gtgaacaaaa aataaaaaag
    27961 tcttgttata gttcgtaaaa ttatatataa ttatttatgt actaatgtgt acacagtaat
    28021 cacacgacaa aagatttaag gaaggtgcta atataatgat agataataaa tatactactt
    28081 actcaaaccc acttacagac agatattgta gcaaggacat gagttatata ttttctccac
    28141 aatttaaatt ctctacatgg agaaggttat gggttgcact tgcagaaggt gaacatgagt
    28201 taggaatcaa tataactgaa gaacaattag atgagctaag agctaatata gataatataa
    28261 attttgatga agctagaaaa atagaaaaag aagtaagaca tgatgtaatg tctcacgtaa
    28321 aagcttatgg tttacaatgt gaaaaagcca aaggaataat acatttagga gcaacatctg
    28381 catatgttgg agataataca gatgttatac aaatgaatga agctttaaaa cttctaagag
    28441 taaagcttgt aaatttaata aacaatttaa aagaatttgc acttaagtac aaagatatgc
    28501 cagctcttgg atttacacac ttccaagctg ctcaacttac aacagtagga aaaagagctt
    28561 gtttatgggc tcaagattta attcttgatt tggaagattt aaactataga atagataaca
    28621 tgaagttaag aggagttaaa ggtactactg gtactcaagc aagtttttta agcttatttg
    28681 aaggagacca cgaaaaagta aaagatttag ataagaaaat ttgtaaaaag atgggatacc
    28741 attcttccta tgcagtaagt ggacagacat atactagaaa gttagattat caagtaataa
    28801 gcatactatc agggatagct caaagtatgc ataagatgac taatgatata agacttttac
    28861 aaagtttaaa agaattagaa gagccatttg aaaaaaatca aataggttca tcagcaatgg
    28921 cttataagag gaatccaatg agaagtgaga gaatagcatc tttatctaag tatataatct
    28981 ctgaatctat aagccctgca atggtacaag ccactcaatg gttagagaga acattagatg
    29041 actcagccaa taagagattg gcaatacctc aagcatttat ggcagcagat gctatacttg
    29101 aaatagggat aaatgtaact gatggtttag tagtatatga aaatatgata aatagacgtg
    29161 taaatgaaga acttcctttt atggctacag aaacaatact tatggaagct gtaaaaagag
    29221 gtggagatag acaggaatta catgaaataa taagagaata ttctatgaaa gctgcctata
    29281 gagtaaagca tgaaggcaag gataataact taattgaact tataatgaat gatgattcat
    29341 ttaaaatgag caaggaagaa atactatcta taatggaccc aaaaaacttt ataggtagag
    29401 ctccagaaca agttgtagaa tttgtaaatg aagttgtaga acctgctata aaagattata
    29461 aggaagactt aggaaaagta gatgtagacc taagagtata gaattgtaca gataaaatat
    29521 aattaaaaat ggctatctta tttataaata agatagccat tttaatgggc tagcgtcttc
    29581 tctccaccgc tgtgaagagt tcttctttac ttactatacc atgaatttaa taaaatagct
    29641 atataaataa tatttaatag gaataatata aataaaaata aaaaaatgat aagattacta
    29701 attaaattta aacattcagc aaaaactatt gtacttgcaa tatttttaat gtaaactgaa
    29761 ataaagttat ttagataatt taataaattt taaaacaacc gaggtgatta tatgaactat
    29821 atagtaaaag ataccataag ttttttagta aaaacatttc ctaagattta ttctagcctg
    29881 tacttagaag acctaaaaaa atttgcacca gattataatg taaataaaac acaattaaga
    29941 gcattagttt tcataaaaaa ttatggagta ataagtatga ctgatttatg ctctaagtta
    30001 aatatagaaa aaggcagttt aactagtatg gttgatgatt taactgataa gaagtatgta
    30061 acaaggaaaa gagatttagt tgatagaaga aaatatctaa ttgacattac tgaagaggga
    30121 gataagatag caactgattt tatggataaa ttaagtgatg gtttaggaga aaaactttct
    30181 aaattaactg aagaagacag aaaaaaatat ttagaagcaa taaatactct tcaatatata
    30241 ttaaacaaag aagaatttag atagaaaaaa tataaaaatt tttgtattta atggtactaa
    30301 gattaattct ttgttattca tttaactata taattataag tctaaataca atctaaaaag
    30361 tacatcttaa attacttttt tataatttct ctaactaagg caagacaagt tttagatgct
    30421 ttaattaaag tgaataaaga ttactggcca acactatata aagaaaatga aaaatagtca
    30481 ggtctaagtc ttaattaata tattaattaa gaaatgtccc cttttcaaat aatatctgaa
    30541 aaggggacat tttatatcat taaatttata taaattaagt ttaaaaaatt atttttgtaa
    30601 agctacatat tgctctaaac cttcttttaa taatgtagca gctctatgaa ggtctttttc
    30661 atttaagatg taagctaatc ttatttcatc acgtcctaaa cctggagtag catagaatcc
    30721 ttcagcaggg caaaccataa ctgtttcatt atctttgtta aattctttta acatccaaat
    30781 tgtgaaatct tctgcatttt caactggtaa tttagcaact atatagaaag caccagttgg
    30841 ttttttacat ataacacctt caaccttcat taattcattg tataatacat ctcttctttt
    30901 tttgtactct tcattaactt ctttgaagta agaaacagga gttttgtata actcaacagc
    30961 tcctatttgc tctaatgtag gaacacaaag tcttccttga cataatttaa ggatttgagc
    31021 gataagacct ttatttttgc aagcgataga accaattcta gcaccacaag cactgtatct
    31081 cttagaaaca ctgtctatta ttataactct atcctgtaca ccctctaagt taccacagct
    31141 tgtatactca agcccatcat aaacaaattc tctataaact tcatctgcta ttatccataa
    31201 atctttttct ttagctattt cagctaggat attaagttct tcttttgtat aaattgcacc
    31261 agttggattt cctgggttag aaagaattat agccttagtt ttatcatcta ctttagacaa
    31321 tatttcttct ttagatggaa ggtggaaacc gttttctgcc tttgttgtaa cagcattaac
    31381 ttctacgttt acagattgac caaatccatt gtagtttgta tagaatggtt ctggaactaa
    31441 tagattatct cctgggtcac aaactgccat catagtgaaa agtaaagctt cactaccacc
    31501 attagttact aataattcat ctttttcaaa attcatatcg taagttttat agtaattttg
    31561 aagtgcttct aataattctg gaataccttc tgatgtagca tattctaaga cttcgctatc
    31621 aaagttttta acagcatcaa aaaatccttt aggagttttt atgtctggtt gtcctatgtt
    31681 taagtgatat actttgattc ctttatcttt tgctgcttgt gcaaatggaa caagttttct
    31741 gattggagag gcttgcattg cactaactct gtttgaataa ttcattttaa taccccctat
    31801 ttaatttaaa tacgtatatt gtattatgta aattgtatgt ttgaatacaa gacatcttta
    31861 caagataata ataacatact tatgggtaaa aatcatcaaa aaaaattaat atagctttaa
    31921 aataaacttt taacaaatta tagtaaaata cccatgttta tgccactaaa ttatgtattc
    31981 ataaattaat ttatagtaag ataatattct gatatactga tagtgatttt ttagttataa
    32041 tctttcagct atagacaaaa tatataataa taaatatgca aaattataaa aaatattata
    32101 aatttattta acagatacga taaatatcat ataattatat taaaggctat taactaagag
    32161 gtgttaatta tgaaagaatt aagaatagat ccaattacca atgatgttgt tatatttgct
    32221 acagataggt taaaaagacc tttagataca gcagatatcc caaatgaaga tgaagaaact
    32281 aatgaatatg atgaagaatg cccattttgc aaaggaaatg aagctcatgc aactgatgca
    32341 ttatttgaaa tagatagtga agaaggatgg cttgtaaaat ctgtctacaa taaatttcct
    32401 ataattgatg atatggcaag agatgtatat ggtgttcatg aagtaatgat agagagcgat
    32461 aaacataatc gtagttttta taacatgagt caaaaagaat ttgaagatgt tttttttatg
    32521 tatagaaata gatttagaga tttgtcgaaa gatgataaag tagagtatgt tagtatcttc
    32581 aaaaacttct tgagaaaggc aggagcatct ttgatgcatc cacatgctca aatattgtct
    32641 atgtctttta ttccacctga aattacgaat gaactgttgg tttcaaagga gtattatgac
    32701 agcaataaaa gctctttgta tgatgattta atagaaaatg aaataagttt agatagaaga
    32761 gttgtttata atggagaagc ttttttggta cttataccat atgcaaccaa gtatagtgga
    32821 gaagtaagaa taatatttaa agataaaata gagtttggtg agttaaatga taataatata
    32881 caggagcttt ctacaatatt tgaaaagttg tttaagaagt tatacaatat caatggatat
    32941 atgccattta atttatgtat tcacactcat ccaacaaaga ttgaaacaaa atcgtatttt
    33001 aatgttcata tgcacataat cccaagaaaa tataattttg gaggatttga acttggaaca
    33061 aatatgtatg tttcttcaat gagccctgaa gatttaacaa aaaagttaaa aattgattaa
    33121 aacatatatt tttaggtatt aagtaaatag taattttaga tgaaattata gtatagcatt
    33181 gttaaaataa aagtgaatta agaatttaca ataaaattgt tgaaaagccc ccatctttag
    33241 ctatggggag tgtgtcaatg tttagatgag gagtataagt atgaaattta tatcatggaa
    33301 tgttaatgga ataagagctt gtgttgggaa aggattttta gactttttca aagaagtaga
    33361 tgcagatata ttttgtttac aagaaactaa attgcaagaa gggcaaatag agttagattt
    33421 accaggatat tttcaatatt ggaattatgc tgagagaaag ggttattcag gtactgctat
    33481 atttacaaaa aaagagcctt taaaagtaat gtatggaata aatatagaag aacatgataa
    33541 agagggtaga gtgataactc tagagtttga agatttttac tttgttacag tatatacgcc
    33601 aaattctcaa tctgaattaa agagactaga atatagaact agatgggaag acgactttat
    33661 agattattta accaaactag ataatcataa gcctgtaatt gtgtgtggag atatgaacgt
    33721 tgcacataaa gaaatagatt taaaaaatcc taaaaataat atgaaaaatg caggttttac
    33781 taaagaagaa agagagaagt tttctaaatt attagacagt gggtttatag acacatatag
    33841 atattttaat cctgataaag aaggtgttta tagttggtgg tcatatagat ttaatgcaag
    33901 aaaaaataat gcagggtgga gaatagatta tttttgtgca tccaaaaaat tagaagatag
    33961 attagtaagt gcggatatac acactgaaat attaggttca gaccattgtc cagttgaatt
    34021 agagataaaa taaaaattaa ttatgataaa aattgggctg tagatataaa tttaaagtta
    34081 actagttttt taatctacat gcctattttt tatctaaata aactctattt gttttttctt
    34141 tgcttaacat tttctaatgt aaattgattt gttttcccca tattataagc taagttaatg
    34201 atttttttct cgtctttagt taattcacga tttaaaattt tcctaaattc atcaaataac
    34261 ttatcataat caactctttt tttattagaa tatcttatag ttttaggttt tatactcgta
    34321 taaagatata tatctgggac tatacttgga ttgtatatct taataaaaac tttagcagta
    34381 taatatgcat catttaaagc attgtgataa gacatttttt catcaagttc taatatagaa
    34441 atagcatttt gtaggccaat gctttttcct gctggattat tgaaatattt agatgcatgt
    34501 tgttgtatat taatataaga tttaggtaag gaatttgatg gtagcttgtg atagttgata
    34561 ttcctgtata attcctttaa atctccagct ccccaaacac ataatatagg gtcttgtgat
    34621 gatataaatt ttataaaatt gttgtagacc tcagggaaag taggcgaatc attaaaatca
    34681 gaatttttaa tattagtcat acgactaata aagggatgta tgtctttata aattgtaggt
    34741 tttacatagc tattaaacgt atctattata ttgaatttag aatccaattt aattgctcct
    34801 atttgtataa tttcaaaagg acacttttca ttggatacag ttttattgag ttttttatca
    34861 aatccttggt taaattccaa atcgaaaatt atgtattcca taaagtttat ctcctaaatt
    34921 tttttattat ttcttttact atagattata ttataaataa aattaaattt tcaaataaaa
    34981 atacttttat tttagtatac cccatatttg taaaaatgtt aaactattgt atgtataata
    35041 ttttttccaa taaaaaatat tgcgaacttt ttatacttga tatataataa tataaataaa
    35101 aacacgaata aaacacgaat aatttgcaag aaaaattcat aaatgtaagg aaaatgaaat
    35161 ttatcttgta tttaacaaaa taaaatatac ataaaaatta tgggagagtg gaaaaatgga
    35221 tagtctatta tacgtaatag agaaagataa acacactaat gaagaattaa gagaaatcct
    35281 aaaaagcaat aaaaatataa gatttgtttc cttaatgggg gttgatttag gaggaaatgc
    35341 aacagatgaa aagattcctg tagaattatt tttggaggat atagataaat ttttggaatc
    35401 agctatacag actgatggtt caagtgttga gctttataat atagctacat taaataatgc
    35461 gaaagtagat ttaatgccag ataaaagttg tcattggtat gtagattaca atatggaata
    35521 tatagacgaa gaagtaggtc tacctgttgg aacattaaag atacctgcat ttttaataca
    35581 tgataataaa aaagtatgtt ctagaggagt acttcaaaaa gcagataagt actttaaaaa
    35641 gtcaatgtat gaaatattta gagaatatcc acatgtaata aataacatag gaatagattc
    35701 agtagatgat atagatgaaa taatgttaac agcagctaca gaacttgagt tctgggttaa
    35761 tactcctgag gataaagctg acttagagaa attatatgta tcacaaagcc taaaagagca
    35821 atactggaaa agaactcatg gtattataag aacttgttta gagaaaagtt taattatact
    35881 tcaaaagcta ggtgtaaacc ctgaaatggc tcacaaagag gtcggaggaa tacaaagttc
    35941 tattagtata gatggaagaa caaaccatgc tatggagcaa ttagaggttt cttggaagtt
    36001 ttctacacca ttacaagcag cagacaatga attattagta agagatgtta tagaggatgt
    36061 atttacatca catggactag aagttacatt taaagcaaaa ccaattcatg gagtagcagg
    36121 aagtggtgga catacacatg taggagtaag tgcgaagtta aaggatggaa gtataaaaaa
    36181 tctatttgct ccaaaagatt taaaagaaga ttatctaagt gaactaggat atggggctct
    36241 tatgggactt ctttacaatt atgaagtatt aaacccaatt gtaacagctt ctaatgatgg
    36301 atttaataga ttagttcctg gatttgaagc tcctgtatgt atagttacat ctttagggca
    36361 tagttatgag attccatcaa gaaataggtc agttcttgtt ggattaataa gagatatgaa
    36421 aaatccaaag actgtaagat ttgaattaag gtcaccaagc cctctatcta acacgtattt
    36481 agtaatagca ggatgttatc aaacaatgtt ggatggtata aaagcagcag ctaagagtgg
    36541 tcttagtaca aaagaacttg aaaaagagtt atctaaaaat gtaggtgaag aaagtttcta
    36601 tttagaaaaa gatagagcat atagagatga aaatgatgta tttgaacatt atagtttgga
    36661 agaaagaaat gcaagatttg gaataccacc agctacagtt tatgaaaata tgaaaaactt
    36721 agaaatatat gcttcaaaat taaaatcttt aaaacaaggt gatgtattta ctgatagtat
    36781 aatagaatca tttaagattg gagctataga taagtggcaa aagaaattaa aaactagaat
    36841 aatagaggct gggattcaaa aaataagaag tattgtcaag atacacacaa aagaaaatat
    36901 ggatgcgctt gatgaggtag tttggaactc aatatcggat ttaaagttca atattatgaa
    36961 ggatacttta actagagaat cactattcac tagagtgaga gaagctatag aaaataagga
    37021 ttaccagact gcttcagatt tacaaataga attaaagaga agtatggaag aaatacaaca
    37081 actgtatatg cagtacaaga aaaatatata ctaatataac aatttgattt tgatatgata
    37141 aaggcaatca agtattatta aacactatga gtaaattctc aagtgtaaaa gcatacttga
    37201 ttgcctttaa ttttatgttt gaaatttttt aatagtacaa tttaactgta atgattatct
    37261 attaattctg atatataatc agcaattttc tctggatgaa tgactgtttt aaattctttt
    37321 aaattttttt tcataaagtt tattatagaa tcaaattcat ttgatactaa tttataaaat
    37381 atgtttttaa ggtctaggtc atcactataa atcatgccaa gacccttatc tattataaat
    37441 ttagcgtttt caatttcttg tccaactttt ggcattttta cgagtactgg agtttgtgat
    37501 tgaatagctt caaatatagt tgctcctcca ggcttagtta gcattaggtc acattctctt
    37561 attagattat acatgtcgtt tacaaatcca agtactttaa tattttttag aggtttttta
    37621 tgagttagat tgtcatataa ttttttgttt ttaccagtaa ctattgtaat ttctatagaa
    37681 ttactatgtt cttcaataaa ttcatctatc caatgcataa aatcctcatc tatatcaaat
    37741 agacctcttc ctccacctag aagtaatagt ctatatttat cacaacatag ttctttactt
    37801 tcaatttgaa atctcttatc aacaggaact ccagtaacct ttatggagtc aggatttatt
    37861 cctttctgaa aaaatctatt ttttatttca ggagaaggaa caaaatacaa atctgtattt
    37921 tcaaaaaccc attccatact atctacaaca tctgttataa ctgtaagtgt aggtatattt
    37981 atatcaggat tttttatctt aaagttattt acacaagcag cagctagtgg aaatgtagag
    38041 ataatcaaat ctggatttat atcagcaata tactcagaaa gtttaggtgt atataattta
    38101 tgagataaat catgtcttga atcaaacgat ttcttaaagt aataatagta attatataat
    38161 ccaggagtat attttgtatt gttttcataa agttttacca taggcttatt catcatggga
    38221 atacttgcat ttataaagtt ttgtataaca acattatagt tactatattt ttcaataata
    38281 cattctttga ctgcttttgc agcacttata tgtccagcac caaattgagc agttaggatt
    38341 aatattgttt tatcatcttt cattttagcc aatttatcac cactttcata aaatatatct
    38401 gattagagta ttatacattt atagaaggat ttaatcaaca agaatattta aaaataacta
    38461 ttgtgcagaa catagtactg tgttattatg aggatataag aagttttaac atagtacctt
    38521 gtaaaacaca atactgtgta tttaaagaaa ggatggagta tatgaacaca caatttagaa
    38581 agggtgtttt agaaatttgt gtacttgctc tcatatctaa gaaagatatg tatggatatg
    38641 agatagtaca taacatctct aaagtaatag atgtaaatga aggaacaata tatcctattc
    38701 taagaagact tacaaaagat ttgtatttcg aaacatatat actagaatct aatgaaggtc
    38761 ctgctagaaa atactataga ataacttcac taggaaaaga gaatttatcc aatctgatgg
    38821 aagagtggag agaatttgta aaggctgttg agattttaat aagtgaagat gagggaggta
    38881 atgaacttga ataaaactga gtttcttgaa attttaaagg attatctaaa aaaagatttt
    38941 tctgagagcg aagttaatga tatattgaga gattatgaag agtatttcgt agatggtctt
    39001 atagagggaa agagtgatat ggagataata gcatcacttg gctcaccaaa atctatagca
    39061 aaagaactta tcttacaaac taaagaaaaa aatattgaag aggaaaaaat aataaataca
    39121 gatgttttga atgataagtt tagtaaattt aaatcagata tgaaaaaagg ttactctatc
    39181 ttaaaagatg aagcaaaaga aaagtatagt aaatcaaaag aaaatataga tggaaaaata
    39241 atgaatacag acatattaaa tggtaaattt agtagattta aatcaaatgt aaaaaaggat
    39301 tactctatct tgaaagatga agctaaggaa aagtacaata aatcaaaaga aaatataaat
    39361 gataaactta caccaagtat agaagaaggc gtaggaggat tatccagaca agttataaag
    39421 gggttattag tagtgttatc tttatttcta attgttccag catttgcgtt tgtatgtgct
    39481 attgtatctg ctactattgc attagtatgc tcattaattg cttttgttat attaattcca
    39541 tttgtgatta aatttatagc aatggttcca gatgttatga tgttttgtat tttcgcaacc
    39601 atagcatttg tagggcttga gatacttgca tggcaaattt tattatttgc cataaaacta
    39661 ggtaaacaat tactaaataa ttatatacat tggataaaga gaaaaaatat ttatataaag
    39721 gcaaatgaaa agatggaaaa aagaaaaaaa gctactttaa atgatgaaga tttgaataaa
    39781 gacattaatg aagattcata taataatgat tactacaata gagaagaaga aagcataaaa
    39841 gaaactgatg aatataatga tgatagtata aattttgagg cgatatataa ggaccttgaa
    39901 gatatagaaa ataagaaagg agaagataaa catgaataaa aaacttgcta tatttgctgc
    39961 agttttattg gtaataggta taatagggac aacatggtca gggattttag ttatgccaag
    40021 cctaataaac tttggtttag aaaaggaagc tgaatttaaa aaagaaaata aactttatca
    40081 agaaaaagta aatattgaca agttagatat agctgttgac aatataaacg ttacaataaa
    40141 gaaaagttca agtgaagatg tgcgtgtaac aacaagagga aataatgagt tttacaaata
    40201 caatgtaact ttaaaagata agactttagt tgtaaaaggt gaaagaaaat atgaaaataa
    40261 aattaaaaag attaaaaatt tcgaccaatt attaaataca tctataaata gtatgttttc
    40321 acatgattat agagaaatta taatatatgt accaaataat gtagacataa atgcatcaag
    40381 tataagctca cacttatttg tatacgataa tgtagcttca aatactataa catataaaac
    40441 ttcttatgga ggttttagta gagctataac agagaacaaa gtaaatagat tagaaaacct
    40501 aaacttaata tctaataaca atcttcactt gtcaacaaaa tcaattttag gcgttaaaaa
    40561 tgtaaacata gaatcagagt cattgtatat atcttcagag aatgaagatg tatttatcaa
    40621 taatatagaa gagtatatac ctgaaaatgt aaatataaaa gagaaaatag gtagaaattc
    40681 aaattatgaa agtgaatttt acttgtactc tgatatgcca attgctaagt tcctggacat
    40741 agaagttcca aattctaagg taagacttga tataccagta aataagtata aatttaattg
    40801 tgatataaag tcaaaagaag caattgaaga atttaataat gatgaagaat atgacaatga
    40861 ttcatatgat tatgaacata atgaagaaca tagcaacaag tatagaaata cgagggaaat
    40921 aaaagggctt ttgaataaaa atctgtcgaa tttagagaaa gaatatacta taaaaataaa
    40981 ttcaaatagc ttagaattgt aaataattta ctataataat tcataaattg atttaaaagt
    41041 ataaaaatat aatctatact atggtataat aagtatcgaa agagaattag gagagggata
    41101 cttatgaata aaatagcagt aagtttttta ataattgcta ctactttatt gagtacggca
    41161 tgtatggatt atagcatcag tgcagttgag ctagttgatt ctaaagaatc agcagttgta
    41221 aagaaggatg aagatgcaaa agaagaaaca actagtaaaa tgattaattc taaaaaaact
    41281 actaaaatac ctatagagat aatttcaaag gatgagaaaa tagtaaagta cttacagatt
    41341 gatgaagaaa gttcacttaa ggataaactg cgattaatct tagatacatt atcaaatgag
    41401 tattttaatg gtttagacat ggaagtagaa gttaaggaaa aagataatct tgttaaaata
    41461 aacttgatag aaccagataa aaaaagtaga gtttcttgga aagatgatta tttgaatgaa
    41521 caaaatataa tatatactat aaataatatt attaaaaatg tcatccaaga agaagataat
    41581 agcatttgga ttgaagaagt agagatatac tacaatggaa aattaataga attaagataa
    41641 aaaaagatgt gtttttaaca catctttttt tgttttttaa ttcttataaa atccttatat
    41701 ttatgattta gaatgattct tgtaaataag tttgacaaaa gaaaggatga aaattatgag
    41761 taattatatt ttgcaggtaa aaggagtttc taaaaaattt aaggagcaga tggcagttga
    41821 taacatttca ctagcaatta aatctaattc tatatatgga ttattaggac caaatggagc
    41881 tgggaaatct actttattaa aaatgataac tgggatttta aatccaactt caggaaaaat
    41941 aatgtttgag ggacatagat ggactagaaa ggatttatca aatattggtt ctcttattga
    42001 gtctcctgct atatatgaga atttaacagc acgagaaaat ttaaaagtcc atactacttt
    42061 acttggtctt cctgactctc gcattgaaga agttttagag actgtagatt taagagatac
    42121 ctttaaaaag cgttcaggtc aattctctct aggcatgaag caacgccttg gtattgctat
    42181 tgcattatta aatcacccaa aacttttaat cttagatgag cctacaaatg gtcttgaccc
    42241 tattggtatt gaagaactta gagaattgat tcgttctttt ccaaaacaag gaattacagt
    42301 tattttatca agccatatct tgtctgaagt tgaacaagtt gtagatgaaa taggaataat
    42361 ttctaatgga gtaatgggtt atcaaggaga agtatcaaaa gaacaaaact tagaagaact
    42421 ttttatgaaa gttgtagctg aaaatagaaa gagagggcag taatatggaa agatttatta
    42481 gagtggaatt tcaaaagatg aaaggaactt ttggaatgaa gttgatatgg atagttccag
    42541 tgttttgtat acttttgtgt ggactaggtg gagggcaaaa tgctgctttc aactggtggt
    42601 atacgatatt tcttccagga gcattaacat taatatcttc tttaatagta ttaaaagatg
    42661 aaaaaagtaa atatcgtggt attttaccat tgccaattga aatgaaagac gtttggactg
    42721 gaaaaatgat ttactgtatt atttgttgtt ttatagcatc aattatttct gcaataggtg
    42781 tagtttttgt tgggataatc tataaagaaa ctatttcaat aggtcaaaat atcattgcaa
    42841 ctatattaat tattttacta tttatgtggc agattcctct ttgtatgttt ttagcttcaa
    42901 aatttggtat ttttgttaca gttctaataa atatgttctt tactattgtt ggagttgctg
    42961 ttttctcaac tacagaaatg tggtatatgt ttccatattc gattccttca agattaatgg
    43021 ctgttgtatt gcatattctg ccaaacggtc ttcctgtacc agagggaagt gaatttttaa
    43081 ataatgctgt tattttgcca ggagtattaa tatctattgt tttatttgta ttatttgctt
    43141 tagctacaag ggtttggttc aataatagag aggtgaagta atatgagaca gttaataaga
    43201 atattttgtt ctgatttaat aaaattaaag agaaatttta taatactaat gcacatttgc
    43261 attgctttaa tggggatggg attgttttta tggtattata aggtttcagg agctgataat
    43321 atactaaaga tagtagcata tttacaagtt atagcaatag cttttccttt attgtcaagt
    43381 gttgtgtgtt caatgtttgt tgaacaagaa tattatgcag ggaattataa acatatgtta
    43441 acaacatcta atccaaaata tcttactctt ataagtaaat atataatctt agtatgtctt
    43501 ggttttgtag caacattagt gtctgtatta ggttttaaat ttggtatatc taaggcttac
    43561 tttacatcaa gcttttatat gatttcaatt ctaattttaa ttgggtgtaa tttatttgaa
    43621 tacatattac atttattctt aagtttaagg ttcggaaaag gaacatcaat tggagtaggt
    43681 atagttgaaa tgttactttc agcattatta ttaactggat tgggttctgg tatttggcag
    43741 tattttcctt gtgcatgggg tgttagattt ataactattt ggtcgtcttt ttcaagttct
    43801 aaaacggttg aatatataaa ggttgaatca ataaaagcat atcaatcaac aggtttaatg
    43861 tgtggttttg taacaatttt agcatttgta attttatgta tttggttttc taaatgggaa
    43921 ggtaaaaaat cagaagaata gagtaaaaat tgactgttta tttatattat tatgttaaaa
    43981 tataacttag caataaaaag atataaaata atcaaataaa aaactggcta ggtattaatt
    44041 atgaattaat taaactattg gaggacaggg tacaaatgct tggaggtaaa aaatctaaca
    44101 acaaaaaagt tgaaaagtta agaactattt ttataaaata tttatcttta ttctttatta
    44161 tgacaatttc aattgtactc cttttaatgt tatcattttc tgtattatta tcatcaggtg
    44221 taattttacc agctaattat gcagaaaaac aatttaataa atataaagaa cagattattt
    44281 caagtgaaaa agtaactgaa gatataattc caagtatata tgagtatggg gtttatactt
    44341 tggatgggag tttaatttca ggtaccttta ataaaaaaga atcaaaagaa gtatggaatt
    44401 taatgagaga tattgaagaa aggcatgcat attcagaaag ttatataaag ttttttaaga
    44461 aagatgaagt ttttataata aaatacaaaa tagtatcaga gtatagttct ccaattttaa
    44521 gagcatattt accaaaacca gagacattgg gtatgattat ttttagtata atatttttta
    44581 ttgaaattgt tatattatca aaagtatttg gcaagaaatt taatattgaa atggagcttt
    44641 taaaaaatac tacagaaaaa atagaacaac aggatttaga ttttgttgta gaatctagta
    44701 aaatttatga aattaataat gtcctttttt ctatggataa aatgaagttg gcgttaaaag
    44761 attctttaga aaaacaatgg atgctagaag aaaatagaaa ggaacagata tctgcactgg
    44821 cacatgatat aaaaacacca ctgacaatta tacatggaaa tactgactta ttaattgaaa
    44881 taaatgaaaa tcctgagtta ttagaataca tggaatatat ctcaaagggt gtcactcaaa
    44941 tagaaaaata tattaatact ttaatagata tatcaaaaac agagaatggc tatatattaa
    45001 ataaagaagc aatcagtatg agtgagttta taaaagatgt cttagtgcaa atagaagcat
    45061 tagctagtac taaaaactta gatgtggagt tttataaaca agataatttg cctaaaaata
    45121 taactataga tagagaactg ttattcagag ctattatgaa tataatttca aatgctatag
    45181 attattcacc aagccagagt aaactataca taagtgtatc agtatgtaat aaatacttaa
    45241 aatttgtagt tacagattgt ggaagtggtt tttctaaagc agatttgtca aaagctacag
    45301 aacagtttta tacaggagat ttgagtagaa attctaaatc tcattatgga atgggactct
    45361 atattgtaaa taatattgta caaaaacata atgggacttt atatattgaa aattctgtga
    45421 aaactggtgg tgctatggta acaattgaaa taccaatagt ttagtaaata atatccattt
    45481 tgtaaatacc taaattttat gatttatagg tatttataaa atggatagtt tttttgattt
    45541 tatatattgg ttaaatctga taaaaagttt tcaaacataa ctccatcatt tctatcagta
    45601 tcaaattgag atgtgtaatt tatagtttta tatataaaat ctgttgcagt attaaccgct
    45661 actcccaaat catgtttatt tactaacata ccacaaagta tagatgtgaa tatatctcca
    45721 gttccactgt aagaacaatt attatatttg actgatgtaa agaatacatg gtcattatct
    45781 ctatcgtaag ccaaatttaa tatattatca tcttctaata taccagtaat aacgactttg
    45841 ctaggtccca aatcagatac agattttgca atatgtataa gctcatctct attataatcg
    45901 cttttggtat aatcatttcc agttaagaaa caagcttctg ttaaattagg agtagttaaa
    45961 tctgaatgtt taactaattc tttaatttcc tgtctcattt cttctgtgaa tattggatac
    46021 ataactccat tatcacccat cacagggtca actacgataa aagcattggg ataatcgttt
    46081 ataaaattag ccactatctc aatttgatgc tttgaaccca aaaaaccact atatatacta
    46141 tcaaaattga cttttaaatt tttccaaaca tttgaatatt ttaccatttc atcagtaaag
    46201 tctaagaaag taaattcagg ataaccagtt tgacttgaaa gtatggccgt tggaaatgga
    46261 caacattgaa cctttaatgc tgaaagtata ggtatagcaa ccgataatga gcattttcct
    46321 attccagata agtcattaat tgctgcgact tttttttgca taaaaaaccc tccattagta
    46381 tgtattaatt ataatgatac caaaatattt atatacatat atattactat aaaaaaaaga
    46441 aaaaagtaga ttataaaata aaaaattgta aaaaaaacag tgtattgata caattaattt
    46501 ttaatattgg acataataaa atagagaatt attaaatatg aaaattacta tatgtgacag
    46561 aatattcttt gtaatttgat ttgtaaggtg tactatttgg gaggtgtagc tttgaaaata
    46621 ctgaaaaata agaataagta catcaaaggt ataatggcat ttgtattttt gtctttagct
    46681 actacagcag gtgtattttt aatcaatgat ttaagtatga aaaatatgga agaaaaagtc
    46741 atggaatctg caaatgttga aggtgatgat gtaaaagacc aatataaact attgcttgaa
    46801 aacttatttg actacagaaa taaggcaata ttagagaaaa atgaaaacat tttaaaaggt
    46861 ctttatgaga cggataaaaa atttggtctg tgggcttatg aaaatgaagt aaaaaagatg
    46921 aagtatttag aaaactggtc tagtaagcaa ggtgtaaaat ttaaagacat aaagacaagg
    46981 gttaagatta aaaaaataaa ggaaaaagaa aaagaccttt atggtataat ctgttcagta
    47041 tcgactgaat ataagtattc atatgaaaat caaaaggaca aagaaaatgc ctttagaata
    47101 ggtacatatc attatctaaa tgtaaaaatt atagataatc aatatgtcat aactaaagag
    47161 tggtatacag acccttttgc agactcttta aatttagaaa atataaaatc tgatgatata
    47221 agaaattata ttggccaaca agatggtgta gagttacagc ttacagatga acaaaaaaaa
    47281 gctatagatt atgcacataa atactgtgga gccgcagctg atgaagaaca tggtatgaaa
    47341 tttaatccaa actatagaga ttataatcca gaaggtggag attgtgcaaa ctttgcatca
    47401 cagataatgt ttgaaagtgg aaggttcaaa aagaactcaa tttggaatta tagcgaaaga
    47461 gcaggtacaa aggcatgggt aaatgcacaa gcttttaaaa attatgcact gtatagtgga
    47521 agaggttcat taattgctaa aggttcatat gaagaagtat acaaagaagc ttataattta
    47581 cgtccagggg attttgttgg ttatgagaag aaaggcagaa taacacatgt ttcgacagtg
    47641 acaggattag actcaagagg atatcctttg gtaacttgcc ataatactga tagaatgttg
    47701 gtgccatggg atttaggctg gagtgataag tccataagat tccatataat aaaaataaat
    47761 tattaaaaaa ttataaagaa aaataaagtg taaaagataa taacgattta aaattataaa
    47821 gtaaaaaaaa ttgattatta atgtataaaa ataataataa ttgacaaaca tagctatata
    47881 tgatagagta gtaataaggt tacagaaaag agtagctaaa tatttgtgtt tttttaggag
    47941 gatttattaa tgaaaactgg tgtagttaaa tggtttaaca acgaaaaagg atttggattc
    48001 atatctgtag aaggtgaagg agatgttttc gtacatttct cagctataac tggagatgga
    48061 tacaaaacat tagaagaagg acaaagcgtt gagttcgaag tagtagatgg agctaaaggt
    48121 cctcaagctg ctaacgtagt tagattataa ttaaaaattc atatatatta gtgttctagt
    48181 aatatgagag ataagccgct aatcatttag cggttttttc agtttttgta aataaaatta
    48241 atagcaaaat aaattaaaat tattaaaata aaatcattaa taatgagata aatatgttaa
    48301 aattaatagt gtagagtaaa attattatgg ctaagtttaa gtcaattaat ttttagtaaa
    48361 ttttctaaaa agagaataag tgatactgat agaccatata aaaatattaa taaagcataa
    48421 taagattaaa atgagcaaag gaaaaacgct tgttacagcg tatagtatta agaatactta
    48481 gaaaataaga aaggagaaag ttactgcaaa aaagtaacat tataaatatt gagtaatatt
    48541 tataagtttt cagtaacggt gggtagtgta atgaacatat tattctttct aacaccaaaa
    48601 agtgaagtag catatatata tgaagactac actataaggc aagccctaga aaaaatggaa
    48661 tatcacaaat actctgcaat tccaataata agtaaggatg gtaaatatgt tggaactata
    48721 acagaaggtg attttttatg gacattaaaa aatgatttaa atctggactt aaagggattg
    48781 gaagatgttc cagtgacaga tataaataga aaaatggata attctcctgt ttccatcaac
    48841 gcagatattg aagatttagt tataaaatct ttaaatcaaa atttcattcc tgttatagat
    48901 gaccaagaca catttattgg gataataaaa agaagagatg taataggtta ctgttatgag
    48961 ataatacgtg gatataaaaa tttagctaat gataattaaa aatcttattt aaacttttaa
    49021 gctgagttct ttacaataaa agaatgataa tatgaaactg aatatttaaa ctttaatata
    49081 aaaagctgtc ttttctaata aatattgtga aaagacagct tttttatgta tgaccttatg
    49141 attaatcgtt gtattttaca aggtttccgt acttagcatt aagagcattt atcttatttc
    49201 cataaacttc attttgtttt tgatataata aacttttttc aacttcagcc ttaacttcat
    49261 caaatgtaga ctctgtactt tcttgaaggt cttctaattt tattatatgg tatccaaatt
    49321 gagttttaac tggttcactt acttcacctt tagccataga gaacacagct tcttcaaatt
    49381 caggaaccat ttgtcctcta ccgaatgttc ctaaatcacc acccatatct ttagatgggc
    49441 aagaagaatg tttaagagct gcatcttcaa aagatatttc ttctgatttt atttgagcaa
    49501 gtatttcttt agctttttca tcactatcta ctaatatatg tttagcagtt gcactttctg
    49561 gtttagagaa agagctctta ttagcttcaa agaattttac tttttcatct tctgttacat
    49621 taacactaga taaaacttta tttatagcaa attgctttaa tacattttct tctatctttt
    49681 tcatttctaa tttaaatatt tcttcttcat ctaatttttc ttctttagca tctaagaaga
    49741 ataattcttg attcactaaa tcatttaata agtgtttttt tccttcttca gttttaaatt
    49801 gcatagcttg ataagggtct aatgatttta atgcattttc aatatcaata ttagttatct
    49861 ctttttctcc aactgttgct aaaacttttt tttccataat agttaactcc ttcatagtgt
    49921 atttcattat taatataaga ctaccatctt aaataatatc agaaaataat gtagatgtct
    49981 aatatttaaa gccatattaa gtcaaataga attaaattta gtagaacaaa gttattacaa
    50041 ttaataaaag tgagctcata atacccacta caccttcgtc atctttaaat ttaagagttt
    50101 ttactattga ataataaagg tatattccag taaaaataat ctttaaatac aagaaaaata
    50161 aactctttgg gtatattaaa aagctaaaaa gtgtaaatat aaaagcaagt agagtactta
    50221 tcctgtaaaa gaaatctatt tgtgtaatgt ctttatattt tatcataaac accgaatata
    50281 aaatgatgaa aacaattgcg acgattgcat atatggtaaa taacatattt tcaagagtac
    50341 catttgaaat tactatccac ttataccaca taattggcca aaataatagt gctaagaact
    50401 taaaataatt atcaaacaac ttttctttat acattcatca aacaaccttt cttaacaaaa
    50461 gcatatattt gtttttagaa ttttaaataa tatgatatca ttattatata ttaatattga
    50521 atttatagaa accaaaattt gttaaaataa atatatagat tttactgtta agccagttaa
    50581 aattactact atttttatta tgaaattgga tcaaatatgt agaaatacgg caaattagtt
    50641 aatattaaat atttattatt tccaagttgt aaagactgtt tttttaatga tagaaattct
    50701 aatctttttt gaaagaaagt aatatccaca ttaagtatgt ctgccatttc ataaacgcaa
    50761 gtgatgccag agttaattat gtttattata tcttcttcag taattaagaa ctcacaagcc
    50821 cattttaagg ctttattttc gcacttatct ataataattt ttgtataata atcgttgtaa
    50881 gaggatacat agtatccaag gctagtgaaa tgatgtccaa gttcttcagc taagatggat
    50941 gtcaattttt ttgagttttg ttttaaatta ctgagtaatg atataatttt aataccatgt
    51001 ttgtttatat atagtccttc taaatcacct gcaatataag tggtataatg aattattatc
    51061 ccttcttgag aagctaattc aaaaagctta tccaaattat tcataaaaat ccccctaaaa
    51121 tagaatgtat gtttgccctt aaattatatt aaaagagcag aaaaatagac tgctcatcat
    51181 atggtttatt tttttttata tttatttagt aaaaattcta tataatcatt aagttgttct
    51241 tgtgcttctt caggtaactc ttcatgtgga ttttttctat gtgcagctac tgtatcaata
    51301 ttttccttaa ctaaggttct tccaagaagg taatcaactg atacattaaa tacatcagcc
    51361 aatttattta aaatgtgttc atcaggaaat ctgttttctg tttcatagta ccctaagact
    51421 ctttgggaaa cgcctacttt ttctccaagt tctctttgag tcaatccaaa ttcctttcta
    51481 agttctctta atcttttggc aaacattata acaccacctt atgtatagat tataacaaat
    51541 tgttctaaaa aataaaacta ataaaatata aaagaatatt tttttctaaa atctattgat
    51601 aaagaacaaa taattctata taatctaagt gaggaagaac aaaatattct taatagtaat
    51661 ggaggtataa aacaatgttt aaaaataact tgaaatatta tagaaaatgc aaaggtatga
    51721 cacaaattca acttgccaga aaggctggaa ttacaaatga ttatatatct caaatagaaa
    51781 gaggcataaa aaatcctgga cttcttatgg ctaagaagat ttctagtatt ttagaacaaa
    51841 atatagaaga agtttttttt atacagttat agaacaatat gttcttgaaa gttgtgagat
    51901 tagtaaaaaa ctgtgcacta aagagattat tgtaaatttg aaactaataa taagtatata
    51961 aaaaggagaa gtactatgga aaacaaaaaa gatatattat ttaaagaaac agataaaaga
    52021 ttacataatt ataagtattt ggatataaag ataaagaata ttaacttgga cataaaaaga
    52081 tgtgagaatg aatactctgg atgtggagca atggtatata cagaaaagac tagtaacaca
    52141 tataacataa gctcttctgt ggaaaatgag gtgttaaaaa gagaggaaag attaagaaaa
    52201 ttaaaaatgg aaaaagaaga tatagaaata gaaaaagaga agatagaaaa tgctctaacg
    52261 tgtctaaatg atatagaaat ggaatttttt aatctttttt ataatagtaa gacaaaaaac
    52321 aatatgacat atatttctat gaaactacac ttagatagaa catcttgcta caatttaaag
    52381 aaaaagatga tatttaaatt gagtgagata ttataaaaaa taggacaatt ttacaacact
    52441 ttatatacac cattgcaaca ataggcaata aaatatgtga gataatgtta ttgtgaaaga
    52501 aatccatatt gaaggaggtg atagattgaa aagaataata ttacctaaaa atatagaaga
    52561 tacttgacag gaataaatga gatatatatt taaaaatgac ttatatcatt tatagtaaga
    52621 ttatcagatt aagcaagaat atttagtgat agtgtggtga ttatttgctt aaatacaagg
    52681 aaatattaga aacaattatt gagattctca aaaaaaactt tactgaaagt atttttattg
    52741 atgatgaaag tgtgcaaggc tctgaagggt cttgtttttt tgtaagtata ctatcagtta
    52801 tttgtacacc tgtaatgtta aatacgaata ataaagatat tgttatctct ataaaatact
    52861 taccaaaacc acagtcaaag agtattagaa tgtatgaagt ttcagatgaa ttaaataagc
    52921 tatttaacag aaatataaag gtaacagaca gaaaattaaa tataacaaag ctagaacaaa
    52981 gtattaaaaa agaagagtca atttatgtat tgaactttac acttacacta aactatctgg
    53041 atagtgtata tgaggaagat atagtatatg aaaatatgga agaaatcaat ttaaatttag
    53101 gagagtgata gtatggctat aggattacca agtatcaaca tatcatttaa ggagctagct
    53161 acaactgtta aagaacgttc agctagagga ataattgcaa tggtgcttaa agatgctaag
    53221 gcactaggtc ttaatgaaat aaatgaaaaa gaggatatac cagttgattt atctgctgaa
    53281 aataaagaat atataaattt agctttgatg ggaaatgtta acactccaaa taaattatta
    53341 gtttatgtaa tagaaggaga agcagatatt caaactgcat tagatttttt agagactaag
    53401 gaatttaatt atctatgtat gccaaaagca gtagaagctg ataagactgc tataaaaaat
    53461 tggataatta aacttagaga tatagataag gttaaggtta aagctgtatt aggaaaagtt
    53521 gtaggaaatc atgaagggat aattaatttt actacagaag atgtgttagt tggagaaaag
    53581 aaatacagtg ttgatgagtt tacaagtagg gtggctggac ttatagcagg tacaccttta
    53641 agtcaatcag taacttatac taaacttagt gatgtagtcg atatacctaa gatgacgaaa
    53701 gttgatgcag aatcaagggt taataaagga gagcttatac ttattaaaga agcaggagct
    53761 ataagaattg ctagaggagt aaattcttta actgaattaa cagcagaaaa aggagaaatg
    53821 ttccagaaaa taaaaatagt tgacacttta gatattatac atagtgacat aagaaaggtg
    53881 ataatagatg actatatagg aaaggttact aacagttatg acaacaaatg tttattgata
    53941 gtagctataa aaagttattt agaagaatta gaaaaatcag cacttataga atctgattct
    54001 actgttgaaa tagattttga agcacaaaaa tcgtatttaa aatcaaaagg agtagattta
    54061 tcttatatga cattacaaga aataaaagaa gctaacacag gttctaaagt atttttaaaa
    54121 gcaaaaataa aagtacttga tgctatggaa gatatagatt tatcaataga aatataggag
    54181 gattattaat atggcaaata tggaagctag aaatgtaatg agtggtactt ggggagaact
    54241 ttggcttgat ggaaacaaag tagcagaagt aaagaagttt caagcaaaga tggaatttac
    54301 aaaagaagat attataatag caggtcaaat gggtactgat acaaagtata tgggatataa
    54361 aggaaaaggc tcaataactc tataccatgt tagttcaaga atgcacaagt taattggaga
    54421 aaagataaag agaggttctg aacctagatt tgttgctata tctaaattaa atgacccaga
    54481 ttcttatgga gcagaaagaa tagcagtaaa gaatatagca tttgatgatt taactttagc
    54541 tgattgggag gttggcgtaa aaggagagat agaagcacct ttcacattta ctgagtatga
    54601 ttttcttgat ataatttagt tttatattta gttttatatt tggttttata ctgatattta
    54661 gtaaatatat acttaataaa ttcagatagt taataagtaa aaaagttagt tgattgaatt
    54721 tgattgataa aggagcaaat aataatgagt gaaaatggat tattaaaaaa tataaacata
    54781 gtagatttac ttttaaatgc agatacagaa aacttagaaa gaccaagtac tatagttgaa
    54841 cttaagagat tatcaactat atttgggcag gaatttaaag taatgtgtag agctttaaca
    54901 ataagtaaag atgaagagat acaaaatact tgtcttaaaa ttgatgaaaa tatgaaaacg
    54961 gatatagact taccggagat gcagatgctt acaattatag aaggtgtttg tgatttggat
    55021 ggaaagcttt tatttaaaaa taaggagcta atggataaat ttaaggctcc aacaccaaaa
    55081 gaattagcaa gaaaattgtt attaccaggt gaaattacca acttatatag aatacttcaa
    55141 gatgttatgg gttatggtaa aaatgcagtg atagaagagg taaaaaacta atagggacgg
    55201 ataccaggac tacaataatg tactattatt ggaagaaaaa aggtataaga ccgtcccttt
    55261 tttatgcaat ggataaaggc gaattaaagc ttattgaagc ttttttcgcc ttagaaattg
    55321 aggaagaagt tgaaaaaatg aaacatggat atggagtgtg tcctttgaca ggaggtggta
    55381 tgtaatggga aatgtgagag aagaaggtat aaatatgtac cttacagata attacacacc
    55441 aaaaatgaat caaattatat cagtaactga taattttagg agagcaactg tggctgtttc
    55501 actttccact aatgtaatgg ctagtagcat aaaaaattct attggaagtg caagtaatag
    55561 agtaaacagt ttaaattcct cgttaagaaa agttcaaact actgctagta gtgtaagttc
    55621 aactatgaca aaattaagtt ctagcataaa tgctgtttca ggagttattg gaagtttaaa
    55681 tggaagtatt atgagactag caataactat agctatgatt attgattatt ttaataagtt
    55741 gattcaaaag aaaaatgagt ttaattcaaa tattatgatt atattaatat ttaaagctaa
    55801 aagtgatgaa gtagaaaaaa ctaaaaataa attacttgga aatttaaaaa agattggtgg
    55861 caagatttgg aatatcgtaa taaaagcaaa agatatgact aagagagtga taagtagtat
    55921 cttgggaaaa ttaaaacaag tagagaaacg tccttatcaa ggaagtatta atcttaaaga
    55981 tatggtgagt agtgctatgg gtagaatttt gcctaagtta atgttgttta aaaatacttt
    56041 ttggagtggt gtaatagcta taaaagatat ggcaagtggc attataagta aagtatttcc
    56101 caaattgaga ttatttgcag gtaaggtatg gagtggtgca atagctgtaa aggatatggc
    56161 aagtggaata cttggttcga taaaagggaa gatatctgat ttgacaaatg gtgctactat
    56221 aggtgtcgct gtgaaaaagg gtgttgattt acttggtcag gaacaaaatc agaaagttgt
    56281 tctagaaagt gtaatgaaaa gaaatactgg aaaagttaat caaatagatg ttgatgatta
    56341 ttatggcagt ttagtaagaa tggcaaatga tacgcctttt gaccctgaag atgttgttgc
    56401 aatgggaact aaagctaaaa tgattagtaa tattactggt ggcaaaaaag aaaaagatat
    56461 aactcaagct atggtagatg ttagagcttt aaatatgaat acaagtagtg aacaagatgt
    56521 atcagcagct ttcttaagtg cagcaaaagg aaacatggaa tctcttaata ctctggtagg
    56581 agaaaattat aaaacttttg atgaagcatt ggaaggcata agtgtaaagc agatggggtt
    56641 agctaaagaa atgagtaata caataccagg tataatatca ggagctcaaa caagcattaa
    56701 caatggcttg aagagtattg ttaaaccttt tgatgatatt ttaggtcaag gactaaagaa
    56761 aataaaaact tttatagaaa gtggattagg caatttagct ggcttatctg aaaaaatggc
    56821 tggtaaaata ggcaatgtaa tgaatggtaa gataattatt ggcaacaaat atgaccagat
    56881 gcaatctaga agtgtaaaaa atggaaaaga gttttctgat tctactcaat atcgaatttc
    56941 taatgaggct gaaaagcgta aaatgatggt tgaaaataag caagaacgtt ttgaaaatca
    57001 tgcagcaaca atgataggga atgcaccaaa agcaattgtt aacgcaggaa gtacactatt
    57061 acaaaatatc gattttacag cattaataga ttcattactt ccagtagtaa acttagtaaa
    57121 taatttacta gatagtataa acaataaatc accaattgca caaggattaa taagtatatt
    57181 tggtacaata gtaactacag cattccaact aatcggacct gtagttgaag ctgttagtcc
    57241 tattatcaca agaattttta cttttttagg tgaatatgca cctcaaataa acaattttat
    57301 agagacactg ggtgttattt ggaaaactgt atgggagacc ttaggacctc tgttggaaac
    57361 tggatggaaa attatagagc caatattggg agcttttttt aacatattag ataaagtatg
    57421 taaaatagtt aaagatatat gcaagtggtg gcaaactatg attaataaga taaaaaatgg
    57481 aagcatcaca ggaacagttt taaatctagt ggaaaagagt aaaaaaaatt acaaagataa
    57541 tccatatgct ggaacaaagg ctggtgattc tggtaaagct tattcaggta agaaaggtaa
    57601 taatgcattt ggattgaact atgttcctta taatgactat caaaccagac tccatgaagg
    57661 tgaaatggtt ttaactaaac aagaagcaaa tcaatataga agcagaaaaa atggtggaaa
    57721 tataaacata gctaagttag ctgatacaat agtgattaga gaagaagctg atatagaaaa
    57781 gataacatca aaattagttg caagtatcca attggcacag ttagggggtg tcttataatg
    57841 gaaatgtggc ttagacaagc tgaagataga tttagatttc cagtatttcc atcttccttt
    57901 agtattaatg gaaaagctgc tgtaaactct tctagtatac tcaaaatagg tgaaatagca
    57961 acttttggtg gtgtagctct taaaagcatt tcaatatcaa gtttttttcc aaataaagac
    58021 tatactttct gtgactatac aggttttcca tcaccatatg attgtgtaaa taagatagaa
    58081 aaatggatga aggaaggttt tatattaaga tttacaatta cggaaacaaa tataaatatg
    58141 gaagtcataa ttgaagggtt tagttatgaa gaaagagatg ggactcgaga tgtatatttt
    58201 acattagatt taaaagagta taaaagaata aagataccaa aagtaactcc aaaacaataa
    58261 ctattataga taataagtta taaataactg ctgatagaat taaatgaaaa ggcaggtgat
    58321 tttttattat taagatttgg gtacacataa aaaacggaag tatatatgac ataactgaca
    58381 tagtagacaa ggtatcatgg tcaggtgatt ataaatctcc atcaaggaca ctagagtttt
    58441 caataataca atcatcattt gatgtaaatt tccaacaaat cgatatacca atagctagta
    58501 cagtctgttt ctatgtagat gagaaagaac tctttagagg aatgataatt aataggtcta
    58561 aagattcaag tagtaatgaa attagttttg tatctaaaga tatgggattt ttacttacac
    58621 aaagtgaagt gtcatacaat tttaaagata agttagttga agacatagca aagcaagtat
    58681 ttgctgaaaa taggctttca gttggaacaa tagcaaagac caatgtcaag tatacaaaga
    58741 tgtttatagg agtaaatggt tatgacacaa taatgagtgc atatacagaa gcaagtaaaa
    58801 agacaaagaa aaagtatatg atagaggcca atttagataa gtttaatgtt attgaaaaag
    58861 gaactgttac attaagtgtt atgtttgaag agggatttaa tattataaat accacctttt
    58921 cggagagcat ggaaaatgta aaaaataaag taatagtggt agaccagtat ggaagcaaga
    58981 ttagcgaaaa aatagataat gaaattttta aggaagtaaa tgtaataatg caaaaagtaa
    59041 ttcagcaaca agaaaatcaa gatgtagata ttgatagcga gtttaatggg atagaaaaaa
    59101 gctgttctct taaaggttat ggagatgtaa gttgtataac tggtagagga gtaaaagtta
    59161 aagattctta tacaaagctt gtaggactat tttatataga tacagacaaa catacttggc
    59221 aaaatggaga atatcaaatt gaacttgaac ttaattttca aaatcttatg gatgaaaagt
    59281 cagcaggaca ggatgaacct aaggaagaaa gtaatttagg gggagaagat tatgcaggag
    59341 gaaaagagtt tacagcagaa tttacagctt actgtcctag aaaagaagaa ggtggagata
    59401 cagattgtag aaagaaaaaa cttgacccat ctaaaaaaac ttgcgctgct cctatggttg
    59461 gtaaatatga gcaaacttat tatacaaaag agtttttaaa taaacatcct ttattaaact
    59521 atggagatga aatacaggta attacaggag tttctggtcg tgatggagtc tataaagtaa
    59581 atgacgtagg acctgcaata actatagaaa agaatggaac ataccatata gatattttat
    59641 ttggaaatgt tgaagaagct agtaaatttg gaagaagaaa aggaaaaatt attattggtg
    59701 gttattctgg taatgtatct gataaagcta aaatagtaat atcagaagca aaaaaacatc
    59761 taggtaaacc ttataaatgg ggtggaaatg gaccaagtag ttttgactgt tctggtttaa
    59821 tggtctattg ttttaaaaaa gttaatgtta gtttgccaag aacgtcaaat caacaatcta
    59881 aaaaaggcaa gaaagtagaa caaaaaaatc ttcaagcagg agatttagta ttttttcata
    59941 atccagtcag ccatgttgga ttatatatag gtaatggaga atttttacat gctccacaaa
    60001 aaggtgatgt agttaaaata agtaagttaa gtagtagaag agattttaat acagctagga
    60061 gagtattata aaaggatggt gatataatgg ctaatccaat aaatgaattt ataggaataa
    60121 taagagaaga aggaaagtat cataatcaac cttctttttt tattggaaaa attaaaagta
    60181 aattaccaga tttaaaaata gagacaaata acatcatatt agaaaaagaa gatattttga
    60241 tagatagttg gatgattgat agacagctag aaacatttga cacagaaaca aatcaagaac
    60301 accagcatga agtaaaaaat ccttttatag ataactttga atctggggat atggtaataa
    60361 tgtttagaat aggcgaaaaa tttgctgttg taagtaagtt ggtgagctta taatgagtac
    60421 aatatttcct tttataggtg ttccagagga ttatatctta cctaaaacag aagaattgcc
    60481 aatctttcgt gaagtggcat gggattttga aaaagatgaa cctattttag aaaaaggtga
    60541 ctttaaaata attgaaaaaa aagaagcctt aaaagtttgg atatacaagt gtataaagac
    60601 aaatagatat gaacatgaga tatactcttt agaatatggg acagagcttt cagaactaat
    60661 aggacaaaaa tatacaaaag gtcttacaga aagtgaagct agtagattca taaaagaggc
    60721 ccttctaata aatccatata tattagaagt aaacgtaaaa agtgctaact ttaacagaga
    60781 cgtattgagt gcaaatgtaa aagtatccac tatctatggg gaggtggaaa taaatgtata
    60841 gtgaccagac atatgaagta ataaaaaata gaactcttga aaatattaat cttgatattt
    60901 ataaaggaga aggttctttt ctaaacaaca tggtatctgg aaataatcta gaactttcaa
    60961 agatatatct agaactttca aagatacata aaatggcttt tatacaagac acatataacc
    61021 agtttcttga taaaagagtc aatgaatttg gtgtatatag aaagttaggt acagagtcaa
    61081 atggagaagt tgaatttatt ggagagaaag gaactgtaat aaataatggc acagtaatat
    61141 catatagaga tttactattt gtagtaataa aagatgtaac tattggtagt gaagaaggtg
    61201 acaatagccc agttcaagct ctggaagttg gtaagaaata taatttacct acaaattgtg
    61261 aatttaaact agttgataat atatctggag taacaaagat tactaacaca agaagttttg
    61321 aaggtggtac agatatagag acagatgaag aactaaaaga aagattttat aaaatccaaa
    61381 gaaatcaagc tacaagtgga aataaagctc actatgaaga atgggctttg gaagtagatg
    61441 gagtctataa tgttaaggtt tatccaagat gggatggtcc gggaacagtt aaggtcttga
    61501 tatttgggaa aaataatcaa gctgttgata cagaaacgat tgaaagatgt cagcaacata
    61561 tagatgaaga gaagcctatt ggaccaacta taacagttgt gacaccatta ccaatagaaa
    61621 taagtataag tgcagtaatg aaactagaag atggatatac attagacaat gtaaaagaat
    61681 ctttcctaga aagtataaat acatacttta gagatattag aggagagata atctatacaa
    61741 aagtaatggg aatacttata aatactactg gtgtacacga tttaagtaac ttacttataa
    61801 atggaagtac agataatata actattaatg aagataaaat acctagtgta acaactgtta
    61861 attttagtga ggtggaaaat caatgaagct aattgataaa ctaccatcat ttgatagaaa
    61921 ttacattgta gaggagatac aaggtgcata cgatacagaa ttaaatattc ttaaagaaga
    61981 tattgatgat acctttaacc aattatttgt tgatacagca acatggggat tagatatgtg
    62041 ggaagacata ctctgcattg aaaaaaaaga acttgatttt gacacaagac gtagcaatat
    62101 aaaagctaaa atgagaagca gaggtactag tactattgaa gttataaaaa gtatatgtga
    62161 ggcatataca aaatcagaaa cagatataaa agtttatagt gatgaattta cattcgtatt
    62221 gagttttata gcaaataact gtgactataa aactctttta gattgtagcg atatgattga
    62281 aagagtaaaa cctgctcact tattacacta tttagaacca ataatactag ataaaagtat
    62341 ggtctattgt ggtggaggta tggtatgtag tgaagaggta aaagttcatc catactttga
    62401 accaattata aaatgtagtg ctgttgtaaa ctgtggagct ggaatgttaa gtagagaaga
    62461 aataaaggtt tatcctttaa gtattaaatg cattgaaaat aattgtaaga ttaatatagc
    62521 tattgcaaat gatacaggcg tagaaaatgt agtagtttat cctaaatcgg aggtggtata
    62581 attggaagaa aaattttata taatattaac caaaattggt agagaaaaaa tagcaaatgc
    62641 aactgcacta ggagagcttg ttggattaac caagtttcaa gttggagata gtaatggaga
    62701 atattatgag ccaacagagg aacaaactgc tttaaagaat gtagtttggg aaggaaatat
    62761 aaattctcta agaattgatg aaaaaaatcc taattggata gttatagaga ctattttacc
    62821 aggaacagtt ggtggattta tgataagaga agctgctgtt ctggataatg agaataatat
    62881 aatagctata ggtaagtatc cagagacgta taaaccacgt gctgaagatg gcagtattaa
    62941 agatttggtt gtaaaaatga ttttacaatt gtcaaatact tcaaatgtta cattagaagt
    63001 agacccgacg ttggtttttg taactcaaaa ggatattcaa gatttagatg ataagtttga
    63061 taaaaatata aaagaaataa aagtaaaaat tggcgaagaa ctcttatcta cagaagctaa
    63121 aaacttatca ggagctataa atgaggtagt agaaaaaatt aaaaatatat ctattgatga
    63181 tgtaatagga ggtcaaatac aaactgaact atctgtatta aaaaatagtt acaataaatt
    63241 atctgaaaaa gtattagata tcttaatata cttagaatta gagtcagaaa tagatgtaga
    63301 tgaagctgga tattggtatg ataccttaac taatgctaaa aacataatag ctatagaagg
    63361 ccttaagtta gatttaaata gaaagtgtat aactggagaa cttggtagtg ttacatttaa
    63421 gaatgtggtg ctaccattta atgcaaatag agttagatat atacatgaaa tggataataa
    63481 ctttgttgaa acaaaatcta atagggcata ttcaattggt cagacagata taactttaaa
    63541 taaatattcg tatgaaataa gataattagg aggtttttat aatgaaaaga actaaactac
    63601 ttcaaagagg taatttcttt ggcgataaaa atatggtagt tgatgaattt gatgaagggt
    63661 atgataatta tgactttatt aattttttta ctggatgttg taactataca tttggtctaa
    63721 aaaataataa tatcttgtat ggatgtggag ataatagtaa ctttcaactt ggattgggag
    63781 aagacaatac aacaagaaaa ttatttacga aaataccaaa tatatctacc aatattaaaa
    63841 aagttgcatg tggagaatct catgcagtta tacttacttc agatggagaa ttacttgtcg
    63901 caggtataaa tacagatggt caaatgggat tgggattaga aaaagtaggg aaaacagttt
    63961 ctacatttga gaaggttcca gaaataaaag gcgtaaagga tattgcatgt ggacttcaat
    64021 caacatatct tttatacaat gatggaactt tatatgttgc tggaaataat ttgtatggtc
    64081 aattaggtct aggaactaat ggagcatctg caaatgtaaa tacatttaca aaagtagatg
    64141 ttgacaatgt aaaggctgta ttttcatata ataaatcagc ttttataata aagaatgaca
    64201 ataaatgcta ttctactggt tttaataatc aaggtcaact aggtttagga gataagaata
    64261 atagagattt atttagttta gtttctatta atgatgttaa gactatagct tgtggttctg
    64321 aacacactgt gttaatgacg tataataatg atatatatgg ttgtggaaag gaaaaatgtt
    64381 ttggaaatgc acttcaatca tcactattta ctaagataga agaagtaaat ataaaaacta
    64441 ttgcatgtgg tcatggtaac actatgctta tagataacaa aggtactttg aaggttgctg
    64501 gaaataatga tatataccag ttgggtatag caaattactc tgagaatata gataattcat
    64561 ttatagattt aaaaaatatt gtagctaaga gtattttcat tggtttatca catagtatac
    64621 taattgattc aaataatgat tcatattgta caggagataa tacttatgga caattaggtt
    64681 cgttttttga tgatatgcac attgtagaat ttaagaaaat ggatagtgaa aaatatagtt
    64741 atagtaatta tataaattta attaaatctg aggataaatt aactttatta aaagaagaaa
    64801 tggaaataaa ggatattgaa cttccactag atatacattc tgtaagagat gtcgttttta
    64861 gtccttattg tactatggtt attttaggga atggagatgt atatggtcta ggaaataata
    64921 gatataaagg aatgggttct gacttaccaa gtcaattaaa tgaattgaca aaattaagta
    64981 tctctaatgt aaagtctata gtagcatcaa aaaatatttc tggaggaata ttctatatta
    65041 aaaatgatga tacttgttat tattctggac caaatagtaa ctcaatagca ggtgttcttc
    65101 cttctaattc agatgtattt aagaaaatat ctatagataa tgtaaaaaaa gttgttataa
    65161 atactgattt atcaaactgg ttttcattaa ttgtaactaa taataaacaa atatacactt
    65221 ctggaaagag ttcaggttat gttaatggac ttagtaataa atcagcaagt caatatactg
    65281 agattggtgt tagcaatgta acagatgcat atagttcata taatgcaaca tttattgtgg
    65341 ctgacgaaaa aaaggtatat gcaactggta taaatacaaa ctatttattg ggtgttaatc
    65401 ctaatgatgg agtcaatata aatttaacat taataaataa ctggttttat gtaaatcctt
    65461 caggagcaag ttatagtaca aattcttgta caaatgatat tactaaaatt aataatatta
    65521 ttatatatga atatatggct atattatgta caaattatgg ttctttttta actggatacc
    65581 atggtacttt atggacaaag ccaagtgatt ctacttatag agttcaacaa caaggaatta
    65641 cacatgctgg atatattagt aattacatat ataactatta tcccacaagg tgtacacaat
    65701 catcatattc tacaaatttt gcctatttgt attatggaga atcaacaagt aatttaaaaa
    65761 atgtaaatcc agataattta cttatttctg gaggttcatc ttatatacat caatatggaa
    65821 ggaattatct taacaatcaa tcatctaata atattgcagc atctaatata aattcaggtc
    65881 ctattacctc tgataaagcc atatttttat ataaagctct attgtattta tcttctaaca
    65941 cgctatatgg ttttgggaat atatctgaaa gtgcaaaaga actagatgtt tcagatacac
    66001 aagatggata taatgccact aattataaaa aggtaatgaa aaatataaaa aatatattta
    66061 tacctcctta tgatttaagt agagataaaa ctagatttgc aatattaact gataagagct
    66121 tatttatatg tggatataac tctaagggta cgcatggtat atcagttaat agtagtttaa
    66181 atttaaataa taagataaat tacaataaaa agaatagcag tagtgaaata tcttctaata
    66241 tacaagaaat atatagccat tcaaagtcta catatttatt aactaataat aatatgcttt
    66301 acagtgttgg tttaaatgat gtaggtcaat taggagtggg agatgagata aatagaaagg
    66361 tatttgctaa aataaatatt gataatataa aatctataag tgtaaataga tttactgaca
    66421 acagtaaaca tgcatttgct ataaaaaatg ataatacctg ttatgctgtt ggtttaaata
    66481 attctggtca gttaggaata ggagataatg taaatagaaa tgtatttact aaaataaatg
    66541 ttgaaaatgt aaaatatgta actgtatatg gaaacacatc tctattatta actaatgatg
    66601 gtcttttata tggagcaggt aataatggaa aaggacagtt aggattgggt gatactacaa
    66661 gtaggaatat atttacacgt atacctataa atggtgttag agatgtatat ctatgtaatg
    66721 atgtatcaat cattgtcaaa aatgataata catgttatgt atgtggattt gtaaatggat
    66781 attttggatt cactgaaagt agtataagta catttacaaa aataaatatt gagaatgtaa
    66841 aatctgttgt gacagcagga agtgaagcta cattttttat aacaaatgac aatatgattt
    66901 atactacagg gaaaaaagag agggtattct tttcaacaga aactaatgat ataaagggta
    66961 tacgagtaat taataatatt ataaatgcaa aaaaaatagt agttaatgga tatacttcag
    67021 ccattttaac aaatgataat aaactatttg ttggaggtct tagtggatat ggaagtataa
    67081 caaataataa caatacaaat agtgtggaag atgttaaaga tgtttttgtg acagctaata
    67141 atacacttta tatagataat aataacaatt tgatatcatc aggtagagat acttatggca
    67201 tatctgatga gtattatatg gatataccag ttccatatta taaagtatct ataaagaaag
    67261 atgttgatac tgtattttct agttacaata ctatatttat taaagatata tatggaaaat
    67321 tttattcttc aacaggagat aacagatata atcatttagg tattcaccat agatatgata
    67381 atgataaaaa tgaagctctt gaaggttccc tacattcata ttttaaaaca gataacacat
    67441 cagataaaat agtttttaat aagaaaaatg aaaagctagt aatgtttaat gataagtata
    67501 taaaaacaaa taataagtat ataaattata aaaacatatt taaagataat tttaagtata
    67561 cttcaataat attgccattt gaggtatctg atattgatat atcaaaaaca cattcattgg
    67621 ctgttgctaa ggatggaaaa ttatatggaa taggaagtaa ttcatataaa gaaattaatc
    67681 aaactcttga agatatagaa ttattaactt ttactgaagt aaatatatca gatgtcaaaa
    67741 aagttgcttg tggagataac tactcctata ttattaagac agataatact ctatggtcat
    67801 atggaaagaa tactgagtac caattgggag ttggtcacaa taatgatgta agagagttac
    67861 aaaaggttac tggattacct tctgttaaag atataagtat atataactca atgacacttg
    67921 ttttaactaa tgagggagag ttgtacgctc aagggtataa tacaaatgga ttgtttggac
    67981 taggagaaag tgaaaaagat aaaataataa caacttttac taaagtatta actaatgtta
    68041 aagaaattaa gtcacataat gatgaccaca tactagtaat taaaaatgat aatagtctat
    68101 ggataactgg taaaaataaa tctatgtata aaatatctat atcaattact gatttatatg
    68161 aatttactaa aataccagtt cctgaacatc taaatgatat tttagatata gagctttcag
    68221 atgatacaat atacatgata acaaaagtag atacaagtaa agcatctata gaaatagttg
    68281 aaaaatcaat atctcaagtg agagttgtag tacaagaccc taataatgtt atagaaaaac
    68341 ttgaaatgtt tataaatgat gaattaatat ctactaagac taatttggaa ataaatagca
    68401 ttgtatttga gataccacaa aataaaatag tattaggaga aaataagata ctgattaaag
    68461 ccagtagtcc tacaggcgat ttatattcaa gtatgtttat atttaaatca gaaacagggc
    68521 ttaaagtaaa aaaggattct attttaatga taaacaataa agtatattca atcataaaca
    68581 ttactgaaaa taacactgat ttaatagtaa cattaaatga gggattaaag gatgatatga
    68641 tggaaaacaa tcctatatat caattaataa ataaaactaa agttcaagta aaaataaata
    68701 aatctgactt attcaaagac atgaaactag ttgaaatcaa aaaatcagac tcaagttacc
    68761 aagaaatcta tgaattagaa gaagccaaca taaaaagtgc tcagcctaaa atcatagtag
    68821 aaaaaggaga taaatggaca gctataaaac gtccatctat gatttttaga tatgatgctg
    68881 aaaacaacga gccacaagct taaaatggag gtgtgaaaat tgtttaaatt cgataaaaat
    68941 aaaatagaac aaatcaaaca aggtagaaaa gtagaaatgc agtataaaga catttcagac
    69001 ataagtatag gtcaagtaaa gcaagatgat gatataacaa ataattttat agcaaatgca
    69061 gaaatatatg agatgttgtt aaatcaaagt tctgtcaatg aagcaagtaa tataagcact
    69121 tttagtgtaa gaaaatctgg aggtgagagt ggaatggtag aagtatatgt agctttaatt
    69181 ttaagaggca aaaaaacaat agaagaagta ccagcagtaa ttagagagca agttagaatt
    69241 agatgtaaag aattagaaat accagttgaa tagtaaattt agaataacta tgtattagtt
    69301 atttttttta tgtaaagtac aaggtcttaa ctttaataag taagccttgt acttattttt
    69361 tgttatatta gaaattgtat atatatttat tatttattca atctataaat tacacctaca
    69421 atttaaagta cagaagatta aattgataat cctgaaaata taatattgca tgatgtaaga
    69481 atataacaaa aattaaagct ataagtataa aaaatttaga caataggagg ctataatgga
    69541 taaattaata accgaattga gtagtctagt ggcaataggt atactatgtg ctctattatt
    69601 taaaaatact atgcaggaga aaaaagaaga tagagacatg tataaaaaaa ctgtagaaaa
    69661 ttttatagaa ttatctacac aacaacaaga aataaacaaa aatatacttg ttcaaatggg
    69721 aataatgaaa acagatgtag aggaaattaa ggaagatgtt actgatataa aaggtatgtt
    69781 acaaaacggt gtataacatg aaagagtagc atcagattat atattgttag gaaaagataa
    69841 agtagtattg tagatagtgc actattttat tgagaaggat ttaatattta aaaatattaa
    69901 ttaaaaaaag t
//
LOCUS       DAEQAF010000008        64256 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.008, whole genome shotgun sequence.
ACCESSION   DAEQAF010000008 DAEQAF010000000
VERSION     DAEQAF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 64256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64256
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.008"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            218..1414
                     /locus_tag="KRN00_000660"
     CDS             218..1414
                     /locus_tag="KRN00_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBH1826545.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            1507..2031
                     /locus_tag="KRN00_000661"
     CDS             1507..2031
                     /locus_tag="KRN00_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBH1826546.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            2056..2232
                     /gene="rpmF"
                     /locus_tag="KRN00_000662"
     CDS             2056..2232
                     /gene="rpmF"
                     /locus_tag="KRN00_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBH1826547.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            2439..2996
                     /gene="fapR"
                     /locus_tag="KRN00_000663"
     CDS             2439..2996
                     /gene="fapR"
                     /locus_tag="KRN00_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBH1826548.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            3007..4029
                     /gene="plsX"
                     /locus_tag="KRN00_000664"
     CDS             3007..4029
                     /gene="plsX"
                     /locus_tag="KRN00_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBH1826549.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            4055..5041
                     /locus_tag="KRN00_000665"
     CDS             4055..5041
                     /locus_tag="KRN00_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBH1826550.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            5150..6079
                     /gene="fabK"
                     /locus_tag="KRN00_000666"
     CDS             5150..6079
                     /gene="fabK"
                     /locus_tag="KRN00_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBH1826551.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            6095..7045
                     /gene="fabD"
                     /locus_tag="KRN00_000667"
     CDS             6095..7045
                     /gene="fabD"
                     /locus_tag="KRN00_000667"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBH1826552.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNAVAKSVIDEASDALNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQVDLKYSACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQDTVPTGVGAMAAILGLDRSILENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLREAGVKLGSELEKV
                     NITKPKIDVVANVNADYYKSEGKELLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            7045..7794
                     /gene="fabG"
                     /locus_tag="KRN00_000668"
     CDS             7045..7794
                     /gene="fabG"
                     /locus_tag="KRN00_000668"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBH1826553.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILVNNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            7848..8072
                     /gene="acpP"
                     /locus_tag="KRN00_000669"
     CDS             7848..8072
                     /gene="acpP"
                     /locus_tag="KRN00_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH1826554.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            8101..9339
                     /gene="fabF"
                     /locus_tag="KRN00_000670"
     CDS             8101..9339
                     /gene="fabF"
                     /locus_tag="KRN00_000670"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBH1826555.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            9565..11283
                     /locus_tag="KRN00_000671"
     CDS             9565..11283
                     /locus_tag="KRN00_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1826556.1"
                     /translation="MNFRLPKKRLPKKIIFICIILISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGSYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGEEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            11314..13314
                     /locus_tag="KRN00_000672"
     CDS             11314..13314
                     /locus_tag="KRN00_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1826557.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            13665..13910
                     /locus_tag="KRN00_000673"
     CDS             13665..13910
                     /locus_tag="KRN00_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH1826558.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            13945..14670
                     /locus_tag="KRN00_000674"
     CDS             13945..14670
                     /locus_tag="KRN00_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBH1826559.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            14692..16005
                     /locus_tag="KRN00_000675"
     CDS             14692..16005
                     /locus_tag="KRN00_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1826560.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVVMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            16211..16750
                     /locus_tag="KRN00_000676"
     CDS             16211..16750
                     /locus_tag="KRN00_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1826561.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            16839..18824
                     /locus_tag="KRN00_000677"
     CDS             16839..18824
                     /locus_tag="KRN00_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBH1826562.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGVKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            19048..20016
                     /gene="spoIIIAA"
                     /locus_tag="KRN00_000678"
     CDS             19048..20016
                     /gene="spoIIIAA"
                     /locus_tag="KRN00_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBH1826563.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            20006..20527
                     /locus_tag="KRN00_000679"
     CDS             20006..20527
                     /locus_tag="KRN00_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBH1826564.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            20544..20741
                     /gene="spoIIIAC"
                     /locus_tag="KRN00_000680"
     CDS             20544..20741
                     /gene="spoIIIAC"
                     /locus_tag="KRN00_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBH1826565.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            20757..21143
                     /gene="spoIIIAD"
                     /locus_tag="KRN00_000681"
     CDS             20757..21143
                     /gene="spoIIIAD"
                     /locus_tag="KRN00_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBH1826566.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            21228..22433
                     /gene="spoIIIAE"
                     /locus_tag="KRN00_000682"
     CDS             21228..22433
                     /gene="spoIIIAE"
                     /locus_tag="KRN00_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBH1826567.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            22493..23110
                     /locus_tag="KRN00_000683"
     CDS             22493..23110
                     /locus_tag="KRN00_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBH1826568.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            23122..23676
                     /locus_tag="KRN00_000684"
     CDS             23122..23676
                     /locus_tag="KRN00_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBH1826569.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            23703..24392
                     /locus_tag="KRN00_000685"
     CDS             23703..24392
                     /locus_tag="KRN00_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBH1826570.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNTDDSDSSKTEDSSNVDKQGGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            24502..24864
                     /locus_tag="KRN00_000686"
     CDS             24502..24864
                     /locus_tag="KRN00_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH1826571.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            24949..25455
                     /gene="nusB"
                     /locus_tag="KRN00_000687"
     CDS             24949..25455
                     /gene="nusB"
                     /locus_tag="KRN00_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBH1826572.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            25439..26509
                     /locus_tag="KRN00_000688"
     CDS             25439..26509
                     /locus_tag="KRN00_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBH1826573.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGDNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSMKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            26506..27711
                     /locus_tag="KRN00_000689"
     CDS             26506..27711
                     /locus_tag="KRN00_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBH1826574.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEKICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            27713..27928
                     /gene="xseB"
                     /locus_tag="KRN00_000690"
     CDS             27713..27928
                     /gene="xseB"
                     /locus_tag="KRN00_000690"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBH1826575.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            27931..28818
                     /locus_tag="KRN00_000691"
     CDS             27931..28818
                     /locus_tag="KRN00_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBH1826576.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            28848..29285
                     /locus_tag="KRN00_000692"
     CDS             28848..29285
                     /locus_tag="KRN00_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBH1826577.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            29319..31184
                     /locus_tag="KRN00_000693"
     CDS             29319..31184
                     /locus_tag="KRN00_000693"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBH1826578.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKVKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDEGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKVLLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            31320..32132
                     /locus_tag="KRN00_000694"
     CDS             31320..32132
                     /locus_tag="KRN00_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBH1826579.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            32152..33831
                     /gene="recN"
                     /locus_tag="KRN00_000695"
     CDS             32152..33831
                     /gene="recN"
                     /locus_tag="KRN00_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBH1826580.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKKVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIESANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            34046..34912
                     /locus_tag="KRN00_000696"
     CDS             34046..34912
                     /locus_tag="KRN00_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826581.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVAVSEINKNIESCSNKLDYLS
                     QELMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECIIDIDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFTSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKINNSNRNQVNYEVSFPKRDIDDIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(35005..35496)
                     /locus_tag="KRN00_000697"
     CDS             complement(35005..35496)
                     /locus_tag="KRN00_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1826582.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(35557..35997)
                     /locus_tag="KRN00_000698"
     CDS             complement(35557..35997)
                     /locus_tag="KRN00_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1826583.1"
                     /translation="MKLNVRIADINNWRDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            36158..37216
                     /locus_tag="KRN00_000699"
     CDS             36158..37216
                     /locus_tag="KRN00_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH1826584.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            37358..38182
                     /gene="spo0A"
                     /locus_tag="KRN00_000700"
     CDS             37358..38182
                     /gene="spo0A"
                     /locus_tag="KRN00_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBH1826585.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            38595..39716
                     /locus_tag="KRN00_000701"
     CDS             38595..39716
                     /locus_tag="KRN00_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826586.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            39734..40609
                     /locus_tag="KRN00_000702"
     CDS             39734..40609
                     /locus_tag="KRN00_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBH1826587.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            40633..41325
                     /locus_tag="KRN00_000703"
     CDS             40633..41325
                     /locus_tag="KRN00_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1826588.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            41333..42157
                     /locus_tag="KRN00_000704"
     CDS             41333..42157
                     /locus_tag="KRN00_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1826589.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            42162..43229
                     /locus_tag="KRN00_000705"
     CDS             42162..43229
                     /locus_tag="KRN00_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBH1826590.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQKAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            43231..43767
                     /locus_tag="KRN00_000706"
     CDS             43231..43767
                     /locus_tag="KRN00_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1826591.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            43835..44440
                     /locus_tag="KRN00_000707"
     CDS             43835..44440
                     /locus_tag="KRN00_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBH1826592.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            44452..45366
                     /locus_tag="KRN00_000708"
     CDS             44452..45366
                     /locus_tag="KRN00_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1826593.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            45408..46580
                     /locus_tag="KRN00_000709"
     CDS             45408..46580
                     /locus_tag="KRN00_000709"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBH1826594.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNRKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            46627..47439
                     /locus_tag="KRN00_000710"
     CDS             46627..47439
                     /locus_tag="KRN00_000710"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBH1826595.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            47643..48968
                     /locus_tag="KRN00_000711"
     CDS             47643..48968
                     /locus_tag="KRN00_000711"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBH1826596.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            49181..50260
                     /gene="mltG"
                     /locus_tag="KRN00_000712"
     CDS             49181..50260
                     /gene="mltG"
                     /locus_tag="KRN00_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBH1826597.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            50432..51106
                     /locus_tag="KRN00_000713"
     CDS             50432..51106
                     /locus_tag="KRN00_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBH1826598.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            51093..52340
                     /locus_tag="KRN00_000714"
     CDS             51093..52340
                     /locus_tag="KRN00_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH1826599.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            52412..54082
                     /locus_tag="KRN00_000715"
     CDS             52412..54082
                     /locus_tag="KRN00_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBH1826600.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDE
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDIDKSMKKELEKNGIMVEEKTMRYAKDGL
                     LSHTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKT
                     VDNKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQND
                     ISKSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNT
                     NEILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGL
                     DEEKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNM
                     NTIKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLN
                     KKAIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(54179..54463)
                     /locus_tag="KRN00_000716"
     CDS             complement(54179..54463)
                     /locus_tag="KRN00_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1826601.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(54486..56003)
                     /locus_tag="KRN00_000717"
     CDS             complement(54486..56003)
                     /locus_tag="KRN00_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1826602.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVRTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKTSDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAIYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            complement(56128..56949)
                     /locus_tag="KRN00_000718"
     CDS             complement(56128..56949)
                     /locus_tag="KRN00_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1826603.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            57140..58567
                     /locus_tag="KRN00_000719"
     CDS             57140..58567
                     /locus_tag="KRN00_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
                     /protein_id="HBH1826604.1"
                     /translation="MKIKKLLTIGLSLSIFIASCPISANALDKIESIKGVDKYETAGI
                     IADKQNYTTAILINADSTMADGLSASGLAGAINAPILLTKKNNIQNATLKRLEKAKKV
                     YIIGGENSIDKYTETVLKGKGIEIKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAF
                     KGEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMNDKLVKDTNSTR
                     LGGTDRYDTNKKIINKFYSGVKEFYIASGTDLVYALVGSTIAKNNAIVLVDNDSNKSV
                     LKSTTKLTAIGNLSDSILQQCLNVTKNIGDSNTGREYTVEDAANAVKKLLGVKKFYYE
                     PNYSEDEDLIFLLDKNFDFSGKEYYVFAYIKQGAEGDVRYCVAKNDMSKVYTYDVNGN
                     MKVCNPDDYKNKGSITEEQAKQIALKECAKRHKVSINNLVVDMIDFRDDIYSGNVYAV
                     KINSKNSNGTFGWFFIDIETGKVYN"
     repeat_region   59523..59815
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=59523..59551
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaag"
     gene            complement(60102..60326)
                     /locus_tag="KRN00_000720"
     CDS             complement(60102..60326)
                     /locus_tag="KRN00_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826605.1"
                     /translation="MDVNQRIKYTRENMNSSQKELLEKTNINTSVMNRIESGERPIRD
                     DGLIIFAKIFGLYTDYILGLSDTEKLNIGN"
     gene            60998..61153
                     /locus_tag="KRN00_000721"
     CDS             60998..61153
                     /locus_tag="KRN00_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HBH1826606.1"
                     /translation="MTLEVKIEVKIIKDVVILNITHWKKETSLLTVKIARSQGDLSYV
                     KYFANES"
     gene            61399..61650
                     /locus_tag="KRN00_000722"
     CDS             61399..61650
                     /locus_tag="KRN00_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826607.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDKEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWEEFNEVAKEVAINIAMKKVETVES"
     gene            complement(62859..63242)
                     /locus_tag="KRN00_000723"
     CDS             complement(62859..63242)
                     /locus_tag="KRN00_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826608.1"
                     /translation="MRKKFFIGILIVLIISVIAILNIKNDKNVFIGESENWKAKFVTT
                     EGHSKLEIKYKNSKDVVEQKFNYSYQFIDGEDAVVVVKNEILEAGQEKAIKIQRPGLY
                     SNRESSYKLIISWNGNEETINLKKK"
     gene            63369..63698
                     /locus_tag="KRN00_000724"
     CDS             63369..63698
                     /locus_tag="KRN00_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826609.1"
                     /translation="MNYRLKKSVTTILSLLIMTILLPTNASASKVEDSSMKVMYSEKQ
                     VTDMDKLYDMAKNGITDVKSSNEKGIIKNARTGESIYVDSISTTQLLEVKQSKNLTSK
                     IYSKTVF"
BASE COUNT        25749 a         6688 c        11490 g        20329 t
ORIGIN      
        1 gaaatacaca atttaccata ctagaaatat gatataatat aaaaaaaaag tatatacttt
       61 tatattaaaa ggtgatatat tatttatgaa aatcgtttaa tgtatacaat aatatatcta
      121 taacaaaata ataaaagata gagttttatt tagacattta ttacaaatca aaatttatta
      181 catattattt ataaaaaaat ctaaggagga aataataatg aaaatattag tattaaactg
      241 tgggagttct tcattaaaat atcaattaat agatatgaat aatgaagaag ttttatgtat
      301 aggattggtt gaaagaatag gaatagaagg ttctatatta aaacatgaaa aagcaggtag
      361 agatgataaa tacgttgttg aacaaccaat gaaggaccac aaagatgcaa tagcattagt
      421 tttagaagct gttgctcatc cagaatttgg tgcagttaaa gaaatgaaag aaatagatgc
      481 agtaggacat agagttgtac atgctggaga aaagtttgca acttcagtag taataactcc
      541 agaagtagaa gaagctttaa aagaatgtat agatttagct ccacttcata atccagcaaa
      601 cataatggga atagatgctt gtaaagctat acttccagat gtaccaatgg taggtgtatt
      661 tgatactgct ttccatcaaa caatgcctaa atcttcatac ttatatggtt tacctcatga
      721 gctatatact aaatatgggg taagaagata tggattccac ggaacttctc ataattatgt
      781 atctcaaaga gcagcagaga tattaggaaa agatataaaa gatttaaaaa tagtaacttg
      841 tcacttagga aatggtgctt ctatagctgc tgttgatggt ggaaaatgtg tagatacatc
      901 tatgggattc actccattag aaggattaat aatgggaact agatgtggag atatagaccc
      961 agctatatta ccattcttaa tgagaaaaga aggtttagat gctgatggat tggataaatt
     1021 aatgaataaa gaatctggag tatatggaat gactggaatt tctagtgact tcagagatat
     1081 agaagatgca gctaaaaatg gagacgaaag agctcaagct acattagaag cgtatgttaa
     1141 aaaagtacaa aaatatatag gcgcttatgc tgctgaaatg aatggattgg atgttgtagt
     1201 atttactgca ggcgttggtg aaaatggaaa ggctataaga gcagatattg cttctaacat
     1261 ggagttttta ggaatgaaat tagataaaga agctaatgat gttagaggaa aagaaacagt
     1321 aatatctact gctgattcta aagtaaaaat gcttttaata ccaactaatg aagaattaat
     1381 gatagctaga gatacattaa gattggtaaa ataattaaat taaacctatg cctatcaagt
     1441 aaaaatactt gacaaacaaa tgctagattt gtataataaa tttggtgata tgttgaggtg
     1501 aacttaatga aagttagcat agaaaaaata aatagaaaag aaactgacaa aatagacttg
     1561 aatttttgtg aaaaaattga tactattagt tattgtgatg agatttacaa attagtatca
     1621 cctgtaaatt taaaagggaa agtgtcaaag actaataaag gtttgtatct agatatagat
     1681 gtcaatttta caattgttga caattgttca agatgtctta aagaagtaga aataccacta
     1741 gagtattcta tacaaggttt tttagtaaaa gaagaagatt atgatgaaga tgagtttgag
     1801 gaatttgatc cttttatatt cgatggtgaa gaaatcgacc ttattgatat aatagaacag
     1861 acattagatt ttaatgtacc tcataaagtt ctttgtagtg aaaactgtaa aggtctttgt
     1921 caagtatgcg gggcaaactt aaatgaagaa gagtgttctt gcagtgaaat tacaaacgat
     1981 gaggaataca tagatcctcg ttttgctaaa ttaaaagatt tatttaatta aattttgact
     2041 aaggaggtgg cgtaaatggc agtaccaaag cgtaaaacgt ctaaatcaaa cacaaaaatg
     2101 agaagagcag ctaactcaaa gatggaagca acaggatttg taagttgccc acaatgtcat
     2161 gagccaaaat taccacatag agtgtgtcca gactgtggat attataaagg taaagaagtt
     2221 gtgtctaagt aatagcttct aaaaagcatg tagagtatac tctacatgtt ttttttgtac
     2281 atataaaaaa ataagatgat ttactagaga aaataagtgg attttatgca tattaaaaaa
     2341 tagaaaaata ataatataag tattgaaaat ttttgtgtgt tactatatac tactattagt
     2401 agctggtact aattacagct ataaaatttg gagggaacat gaaaaagaaa agtaaagccc
     2461 aaagacaaaa agagcttata gatatgctaa agacagatcc tttttatact gatgaagaat
     2521 tatcaagtct gtttgatgta agtatacaga ccataagatt agatagaatg agtctaaaca
     2581 taccagagct aagagaaaga gtcaaatcaa tagcagaaac tcagagttca aaagtaaaga
     2641 ctttaggagt aaaggaaatt acaggagaaa tcattgattt atctgtaggg cgattaggta
     2701 tatctatgtt agaagttaca caggacatga tttactctaa gactaatact ttaaaagata
     2761 cgtatatttt ttctctagca gattcattgg caatggctat aatagatgca cctaaggtta
     2821 ttatgagagt tgcaaatgta aaaagtttta agttgataga acaacaagat aggcttatag
     2881 caaaagcaga agtgtataga aatatagata aaaagcatta tgtaaaagtt gttatcaaca
     2941 ataaagccca agagcaaata tttagaggaa agtttatctt tgaagaatta gattaggagg
     3001 gaaattatga aaatagtaat tgatggaatg ggtggagata atgcacctaa atctaatgta
     3061 gaaggcgcag taaatgctat aaaagaatat caggttgatt taataatcac aggagataaa
     3121 gatttacttg aaaaggaatt ttcaaattat gaatttgata gaaataaatt agagatagtt
     3181 catactactg agattataga aaacgaagat aaaccagtaa aggctataag aagtaaaaaa
     3241 gattcatcta tggtagtagc attaaatctt gtaaaagaag gaaaggcaga tgctataata
     3301 tcagctggaa atacaggagc cttacttgct ggtggattat ttgttgttgg tagaataaaa
     3361 ggaatcgata gaccttgctt atgttcagca ataccaaatg taaagcgagg aatgacactt
     3421 atagcagact gtggcgcaaa tgcagattgt aaacctaaga atctagttga atttgcagct
     3481 atgagtaata tttattcaag aaaagtttta ggtcttgaaa atcctaaggt agcattagca
     3541 aatgttggac tagaagaagg caaaggcaat gatttagtca aaaggtcata tgaagaaatt
     3601 aaaaaattag atttaaattt tatagggaat gtagaagcta gagaagttat aaatgcatac
     3661 acagatataa tcatatgtga tggatttaca ggtaatatat tacttaaatc tgctgaaggt
     3721 gtagcacttt cagttatgag tcttataaag gaaactttta tggccagtac aaaaagtaaa
     3781 ataggagcat tacttataaa ggatgattta agaaaattaa aaagttttat agattattct
     3841 gagtatgggg gagctccact tttaggtcta aatggaggag ttataaaagc tcatggtagt
     3901 tctgatgcta aagctataaa aaatgctata aatcaaggaa taaaattttc aaagggaaaa
     3961 gtcgttgaag atattaacca atttataagc aaatacaatg aagaaaataa aaataacgaa
     4021 gatgaataaa ctcgttttgg aggtttaata tataatgaat acaaaggctg gaatattagg
     4081 agtaggaagt tatctacctg agcaatcata tgataatttt cacttcgaaa aaataatgga
     4141 tacatcagat gagtggataa gtactagaac tggtattaag gaaagaagat ttgccaaaga
     4201 gtctgaagca acttctgact tagcatctaa agctgcctta aaagctatag aatgtgcaaa
     4261 gttaaacgta gaggatatag agctgattat attagctaca attactcctg atatgtcttt
     4321 gccttcaact gcatgtatag tacaagatgc aataggagca gtgaatgcta ctgcatttga
     4381 tatatcagca gcttgttctg gatttgtata tggagtaact attgcaaagc aatttgtgga
     4441 aacaggttgc tataaaaatg tgcttgtaat aggagcagaa acttgttcta agtttttaaa
     4501 ttatgatgat agaacaacag cagtattgtt tggagatgga gctggagcag ctgttattgg
     4561 ccctgtaaat gagggtggaa tactgtctac acatatgggc tctgatggta aaggaaaaga
     4621 ttgtttaaaa gtacctgctg gaggttcaag acttaaggca agtaaagaga ctgtagaagc
     4681 taatctacat acaatagaaa tggcaggtag tgatgtgttt aaatttgcag ttagaaagat
     4741 ggcagaaact tctttaagag ctcttgaaaa agcaaatcta aatacaactg atatagacta
     4801 cttagtgcca catcaagcta atataagaat catacaagct tcttctaaga gattagagct
     4861 tgatatgaaa aaagtttatg taaatataga caaatatgga aatatgtctg ctgcatctat
     4921 accagtagca ttagatgaag cttatagaga aggtaaaatt aaaaagggtg ataatgtagt
     4981 tttagttggc tttggtggag gtctaacttg gggggcttca gttgtcaagt ggactttata
     5041 gtataaaata tctaaaatga tttaattaac aaaattaaac ttatacacaa aataaagttg
     5101 attaataata aaaagtttac ttttatgatt tcaagtgaag gagaattgta tgaataaaat
     5161 ttgcaaaata ttaaatataa aatacccagt tatccaaggg ggaatggcat gggtagctac
     5221 tgcatcatta gcaagtgctg tatctaatgc aggaggactt ggcataatag cagcaggaaa
     5281 cgcaccaaaa gaagctataa agaaagaaat tgttgagtgt aaaaaattaa cagataaacc
     5341 ttttggagta aatgtaatgc ttatgtcgcc atttgttgat gatataattg atttgattat
     5401 agaagaaaaa gttcaagtta ttactactgg tgctggaaat cctgcaaagt atatggatag
     5461 attaaaggaa gctggaacaa aggttattcc tgtagtacct acaatagctt tggcacaaag
     5521 aatggaaaag ctaggagcta cagcagtaat agcagaaggt actgaaggtg gaggacatat
     5581 aggagaactt actactatgg tcttagttcc acaagttgct gatgctgtaa acatacctgt
     5641 aatagctgct ggaggaattg tagatggtag aggaattgca gcatcatttg cattaggtgc
     5701 cagtgcagtt caagtaggaa ctagatttat ttgcagtgaa gagtgttctg tccattcaaa
     5761 ctataaaaac ttagtactaa aagcaaaaga tagagatgca attgtaacag gaagaagtac
     5821 tggtcatcca gtaagaacat taaaaaataa actatcaaaa gaatttttaa agatggaaca
     5881 aaatggagct actcctgaag aattggataa aaaaggtaca ggagctttaa gatttgcaac
     5941 agtagatgga gacatagaaa aaggttcatt tatggcaggt caaagtgctg ctatggtaaa
     6001 agaaataaca ccttgtaagg aaattataga ggctatggta aatcaagcaa gagagattat
     6061 gccagcaata gaactgtaaa tcaggaggag caagatggga aaagttgcat tagtattccc
     6121 tggtcaagga gctcaatatg taggtatggc caaggattta tatgaaaata atgctgttgc
     6181 taaaagtgta atagatgagg ctagtgatgc cttaaatatg gatttaaaaa accttatgtt
     6241 taatggaaat gaagaagaac tttctaaaac tgaaaacact caacctgcta tggttacaca
     6301 tagtgtagct gtattaaaag cagtacaagc ccaagtagat ttaaaatata gtgcatgttt
     6361 aggtttatct ttaggagagt atagtgcatt ggttgcagca gatgcaattg actttaaaga
     6421 tgctgtatgc ttggtcaaaa aaagaggtaa gtttatgcag gatacagttc caacaggtgt
     6481 tggagctatg gcagcaattt taggtctaga tagaagtata ttagaaaatg tagttaaaga
     6541 tatacaagga ggtattgtgg aagtagcaaa ttataattct cctggtcaaa tagttatatc
     6601 tggtgaaaat gaaaagatag aagaagcaat ggtgaaatgc aaagaagcag gagcaaaaag
     6661 agctgttaaa ttaaatgtaa gtggaccttt tcactcatca atgctaagag aagctggagt
     6721 aaaattaggt agtgagctag aaaaagtcaa cataactaaa cctaaaattg atgtagtagc
     6781 aaatgtaaat gcagattact ataaaagtga agggaaagaa ctgcttataa aacaagtaag
     6841 ttcatctgtt ctttgggaag attctataga aagactttta aatgatggat atgatacttt
     6901 tatagaaatg ggacctggaa aaactttaaa agcatttatt aagaagatag cttccaataa
     6961 aaaagcaaat gtcaatattt ataatataga tggtatagat tctcttaatg aatttgtaca
     7021 aaattataga aatggagaga tataatgata aatcttacag gacaagtagc agttgttact
     7081 ggtggctcta ggggtatagg aaaagaaata gcaaaaaaac tagcatcttt tggggctgat
     7141 gtagtaatca attatacttc taaagaagat gaagcactaa aaactaaaaa tgaaatagaa
     7201 agtatggggg taaagtgtac ctctataaaa tgtgatgtgt ctaaatttga tgaagtgaat
     7261 caaatgatag attctgttgt aagcgaattt ggaaaaattg atatattggt taataatgca
     7321 ggcataacta aagatggtct gcttatgaga atgaaagaag aagattttga tagagttata
     7381 gatataaact taaaaggtgt ctttaattgt acaaaagcag ttactaaacc tatgatgaaa
     7441 aagaagtatg gaagaataat aaatatgact tcagtagttg gaattatggg taatgcaggg
     7501 caaactaatt attgtgcatc aaaagcaggt gtaattggat ttacaaaagc ttctgcaaga
     7561 gagttagcat caagaaacat aaatataaat gcagtagcac ctggatttat agaaacagat
     7621 atgactaaag tactaagtga tgatgtaaaa gaatcaacac tagcaaacat accaaagaaa
     7681 tcttatggta aaccagaaga tgtagccaat gccgtagcat ttttagttag tgacatgtca
     7741 agttatataa caggacaagt aataaatgta gatggtggaa tggtaatgca ataataattt
     7801 aaaaagtaga gaaatctatt aaaataaaaa attttaggag gtacacaatg tttaataaag
     7861 ttgtagaaat aataatagag caattaggag tagaagataa agaaataact atggaaacat
     7921 cattaatgaa ggatttagaa gcagattcat tagatgcagt agaaataata atggcacttg
     7981 aagatgaatt tggtatagaa ataccagata cagaagcaga aaacttcaaa tctataggag
     8041 atatagttaa gtatatagaa gctaataaat agtcgagctt taaaaaagtg gaggtatccg
     8101 atgaataaaa gagtagtaat aacaggactt ggatgtgtta cgccgttggg aacaggaaaa
     8161 gaagagttct ggagtaatat aaaatctgga gtatctggta tagataaaat aactaatttt
     8221 gatgctagca catatcaaac tcagatagca ggagaagtta agaattttca tccagaagaa
     8281 tatataagta aaaaagaatt gaagagatta gataaatttg ctcaatttgc aatagtatct
     8341 gctaaattag cagttgaaga tgcaaatctt gatttagata aagttgatag agaacgtttt
     8401 ggtgttataa taggttctgg aataggtgga gttgaagcta tagaaactca acataaaatt
     8461 cttttggaaa aaggaaataa aagagtaagt tcactttttg tacctatgat gataggaaat
     8521 atggcagctg gtcaagtttc aatattttta ggagcaaaag ggcctaacac taatgtatgt
     8581 acagcttgtg catcaggaac tcattcaata ggtgatgctt ttaaggtaat tcaaagaggt
     8641 gatgcagaca tcatggtagc agggggctct gaagctgctg taacaggtct tgcttttgct
     8701 ggattctgta acatgaaggc tatgtcaact agaaatgatg accctaaaac tgcatcaaga
     8761 ccatttgata aagacagaga tggttttgta atgggagaag gagcaggtat tgttatctta
     8821 gaagacttag aacatgcttt agcaagaggc gctaaaatat atgcagaagt agttggatat
     8881 ggtttaactg ctgatgcata ccatatgaca actccagctg aaaatggaga gggagcagct
     8941 aggtctatga atatggcttt gaaagatgga aatgttccat tagaagaagt agattatata
     9001 aatgctcatg gaacttcaac ttattacaat gatttatatg aaactatggc tataaaaact
     9061 gtatttggag aaaaggcata tgacttatgt gtgtcatcaa caaaatctat gactggtcac
     9121 ttattaggag catcaggtgc tatagaggct gttgtttgtg ctatgagtat agaagatagt
     9181 tttgtgcctc caactataaa catacaagaa gttggtgaag atttggattt agattatgtt
     9241 ccaaatcaag gtaaagaaaa aaatattaga tatgcactat caaattcttt aggatttggt
     9301 gggcataatg ctacaatagt actaaaaaaa tatgtataaa taaatattaa atataaaact
     9361 aaaaaacaag cacttgtttt aactgtataa atttatatta gcttaaattt aaagtctcct
     9421 aaattatttt aggagacttt tttattaaga tttaagtcta gcatatgttg taaatcattt
     9481 tgatatattg tattattaat tattaagagg ttatttatat atgcaagttt tcattctaca
     9541 atatacaaaa ggaggactaa aattttgaat tttagactac caaagaaaag gttacccaaa
     9601 aagataattt ttatatgtat aatacttatt agtattattt tgtttataaa gtatgaccaa
     9661 aatggattga aagaaagaga aattataaat aagggaaaat atatgtctga aagccttgtg
     9721 gcagataagg agtatgatga agcaaaaaaa gtggttaaga cttctttcga atctattcca
     9781 gaaaaaaaat acaataaagt atataatgaa gtttgggata tgttaaagac tatttcatat
     9841 gttccagatg gaacgaagat agtcattgat tctttagaaa agatgagaga atcagatgtg
     9901 aaattatctg atgaatgtag atttaatata gaaaaaagat tagcatcagt gtatataatg
     9961 gataataatt attctaaagc agtagattta actgtaaagt ctataaagtt ggctgagaaa
    10021 ttggggaata attatgaaaa agcaagacta gatgttgatt tggcgagcat atttttaaaa
    10081 ataggtagct atgaaacagg agagaaatta ataaaggatt cttttaaaat agatattgat
    10141 gaaggtgaaa aaaatggaat ggttagatta tatgctatta taaatctagc agaaatatat
    10201 gtagaagagg gagaatatga taaagctatt gaaataagta gcaggataaa agattataaa
    10261 aagtttgtaa atacggataa ttacaatgat tttgatataa tggcctctat aatgcagtca
    10321 aatgcgtatg tgggcaaaaa taatatacaa aaggcaaaga cttttttaga aaaagctgat
    10381 tatcttataa aatcagatag aacagtttat atattagata aagatatgta ctattatatg
    10441 gcaatgggaa acttagaata taaaagcgaa aattataatt ctgcaataga taattataaa
    10501 aaaagtttag agatatctac taaaagaaag ttaacccagg agaaaataaa aaatttaaat
    10561 aagatattaa atatatatga aaaacaagga aatatagaat ctttaaatga gtatcaaaag
    10621 atgttaataa atgaatataa agagaacaaa agtataagag attcagagac tagtttctat
    10681 ataattgata aagtatcaaa cgaaagtaag ctatttgaaa aaactaaaaa agaaataaaa
    10741 tattataaaa tattatttac agtaatttta attgctatat tagggtctac ttttttatac
    10801 aaccgattga agtattttaa agcacaaaat ttacatgatg gtcttacaaa tgtttataat
    10861 agaaaaagtt ttgatattat gtatgaaaag tacagagaga aagatgataa ttttgcactt
    10921 gtgatgatag atattgataa tttcaagctc ataaatgata attatggaca taaatttggt
    10981 gacactgtta taaagggaat aacaaatacc atttgtgtta tgttagaaca agatgataaa
    11041 gtctttaggt acggaggaga agaattttct gtattaataa gaaataaatc tggtgaggaa
    11101 gtagcagata taattgacag tataagggtt gcaattgcaa ataaaaaatg gaatgatgat
    11161 gtgactgtga ctataagtgc aggtgtagct catgtttcag atagcaaaga tgtactagaa
    11221 gaagctgata aaaatttata taaagcaaaa caacttggta gaaataaagt agtatataag
    11281 taattatata ctatataaat aagaggtata aatatgaaac aatcaatagc tatagtaact
    11341 gataaaataa ctaaactatc atctttctta gaagaaaata tacgtttggt tttaggtaat
    11401 tatattgata taaaccacta ttatctggaa gttttaaaag agaatgataa aatacaaggt
    11461 gattttgtac tagtaatgaa tgatgataga ttaaacagta tgagaaagca tttagtacaa
    11521 gatagtaaga ttatagtgat aaggagaaca cttaaagaaa atgaaatata tggattattt
    11581 tcaataccaa atggaactga agtattggtt gtaaatgata caaaagaaac taccttagaa
    11641 acgataagct tattttacaa aataggagta aaaaatttaa agtttactcc atatattgaa
    11701 ggaaaaattt ataaaaatat agacatagct ataacacctg gagtaaaggg aaaagtacca
    11761 agttatataa ataaagtaat cgaccttgga aatagatata ttgatatatc tacctttata
    11821 gaaataataa atggtcttag aatagatgtt aaagaaatac gtaaaaattt aatggcatat
    11881 tctgagagtt taataagttt agataatgga gttaaagata attataggca actgttttta
    11941 aaaatagaag aacaagatgt tatattgaat ctatcaaaag atggaataat atttacttca
    12001 gcagatggta taataaacac atttaataaa gaagctttaa aaattttagg tataaatgaa
    12061 aatccacaag gcaaaaacat agaagatatt atttctgaag atttaaatat tttacttgaa
    12121 gacaaagaaa taattgatga agtggtattt acaaataaaa aatatataaa tgtaaataaa
    12181 aaaagtattt tttctatggg gaataaagct gggatatatt ataacttaca agaaataacg
    12241 tatataaaaa aattagaaca aaatcttact aataaattaa gagaacaagg tcagatagca
    12301 agatatacat ttaaagatat aaaaactaaa aataaaaata tggtaaagtg tgtagaattg
    12361 gctaaaaaaa tatctaaatc agacctttct gtattaataa taggagaaag tggtactggt
    12421 aaagaattat tatcacaatc aattcataat gcttccaata gaagtaatca accgtttata
    12481 gcagttaatt gtgcagcagt tccagatagt ctattagaaa gtcaactgtt tggatatgaa
    12541 aaaggctctt ttacaggagc tttaagagaa ggaaaaaagg gtctatttga acttgctaat
    12601 aatggaacta tatttctgga tgaaattgga gatatgcctc cattgctaca gacaaagtta
    12661 ctaagggtat tacaagaaaa gcaggttatg cctataggtt cccataatgt tataaacata
    12721 gatgttaggg tcatagcagc aacaaacaaa aacttactaa agatgattag agaaggaaaa
    12781 tttagagagg acctgtatta tagactaaat gtattgccaa tagatgtacc atcattgagg
    12841 aatagaaaag aagatataat aacacttatg aatttctttt tgaaaaacaa tataagactt
    12901 tcgccagaag ttataactat tttagaaaaa tataattggc caggaaatat aagagagtta
    12961 caaaatgttg cttcttatgt aagtctaatg tgtgatagta tggtttttag agatgactta
    13021 ccaccatata taagggtaga atgtgccaac aattatgaag atggatttgg ttatacaaga
    13081 aaagaatttg aggaaatact gaggattcta tatgaaagaa gagagtcatc ctctggaatt
    13141 ggaagagggt ttataatcga aaagcttata caggaaggta ttgagatttc tgaaagcaaa
    13201 gttagaaagg tgctatctta tttaagtgaa tgtggataca tatcatctaa atctggtaga
    13261 ggaggaagtc aaataacctc agaggggata aaactttata ataatataaa ttaagctaag
    13321 tatttgatat tgaaatcaca tattttgaat ttagatattt aaataataat aaacttttat
    13381 atttatagag attaatttat attatgtcag aaagaatatt gtaatttata attaaatatt
    13441 aataggtttt taaaatagga ttagataggt aataggttaa gttagaataa cccattacct
    13501 atttttattt gtaagaaaag tgtacataga attagaagta aaaaatacaa ctaataaaac
    13561 tattgaaaat actagataaa taataaataa aaataattat agattttggc atacatattg
    13621 ctaattatag agataagacg acaaaataat tgggaggttt aatgatgaaa tacaaaacaa
    13681 cagggacttg tgctacagaa attgaatttg aagtaaaaga aaataaagtt acaaatgtaa
    13741 actttatagg tggatgtgat ggaaatttaa aagggctaaa agtattagtt gaaggcatga
    13801 atatagaaga tgtaatacaa aagttaaaag gaatagagtg taaaacaaag ccaacatctt
    13861 gcccagacca actgtctcta gcattggaaa attatatgaa tataaagtaa tacataaaac
    13921 aatcgattag ttaggagttt aattatgaaa ccaataatag ggattttagg aaatttaata
    13981 ataatggaaa atggtatgtt tccaggtctt gaaaggtcat atgtaaataa tgattatata
    14041 aatgcagtgc taaaaggtgg cggtagtcca gtaataattc ctgtaaatac agataaagaa
    14101 gttataaaaa aacagattga aatggttgat ggagtcttaa tatctggggg atgggatatc
    14161 aatcctcaac tgtatggaga agaaacaaga gaagaaacga catttatata tccagaagtg
    14221 gatgaatttg atttaattgc aataagtata gcattagaac ttaaaaagcc tatattaggt
    14281 gtatgtaggg gactacaaat tttaaatgta agtttaggag gaactttata tcaagataat
    14341 aatcttatag aaggaagtta tataaaacat acacaatctt ctaaaagaca tgtagctact
    14401 cataaagttg atgttaaaga aggaagtatt ttagagggaa ttttaggaaa acaattactt
    14461 acaaatagtt atcatcatca aagtgtcaat cagcttggaa aaggattaaa agccatagca
    14521 tactcaaaag atggtataat agaagctatt gagaaagagg atgaaaattt tgtagtagga
    14581 gtacagtggc atccagaaat gatggtagat tactgtgata aaatggaaaa actatttaaa
    14641 tattttataa atatttgttc gaatttataa tatactttgg ggggattgaa catgaacgaa
    14701 aagaacaaaa tgggattaat aagtattata cttttaggta ttaatgcagt agtaggagct
    14761 ggagtttttc tattaccagg agatgcaatg aaatcatttg gtgtagcaag tatatttgta
    14821 tatatatttg atatgttgtt agttttatct atggcattct gttttgctga ggttgcaggt
    14881 aaattcaata aaaatggtgc tgcctatgta tatacaaaag aagcttttgg agatttttgt
    14941 ggttttgaag taggtcttat gaaatgggta ataggatgta tttcttgggg agctttaata
    15001 gtaggttttc ctacatcatt atcagcagta tgggctccag caggtgaacc acatatacaa
    15061 aaaattataa ttgtagtcat gatagttggg cttacaatta taaacttatt aggtgtatct
    15121 ctatcaaaaa ttgtacaaaa tgttataact gtaggtaaac taattccatt aatactgttt
    15181 ataggaatag gtatattttt tataaaagga gttaatttta cttcttcaac aatggtacct
    15241 ccaggagctg gagcaacaga gtttggagca gcagcacttt taatgtttta ttcatttaca
    15301 ggatttgaat ctatagcagt tgcagcagaa gatatggaga atccacaaaa aaatatacca
    15361 atagcaatta taagtgtaat agtaattgca tcaataatat atatattaaa tcaagttgta
    15421 tgtgttggta tactaggaga ttcgttatct agtacatcta caccagtggc agatgctgca
    15481 agaatatgct ttggaaatat gggagctgga ttggttacct ttggaacctt ggtttctgtt
    15541 ggtggaattt gtatgtgtgg tgcttttgta aatccaagaa gttgtgtagc tttagctgat
    15601 gataaaatgt taccgagaat atttgcaaga aaagataaaa aaggtacacc atatgtagcg
    15661 ataatagcta ctatgttaat cactatacca atagctctat ctggaagttt tgctgaatta
    15721 gcagcaataa gtgcagttgc tagattcata caatacatac caacatcttt atccgtatta
    15781 gtgtttagaa agaaaagacc agaattagta ggtactttta aaactccttt tggagcagtg
    15841 attcctctaa ttgctgtatg tgttggaaca tggttattat tccaagcatc tatgcatcaa
    15901 ttaattatgg gattaggagc tttggcaatt ggagtaccat tatactttat aatgaagtct
    15961 tataatagaa aagtctatgg tgaaaattta aagaaaatag tttaattatg ttataacagt
    16021 ttattgagtt aaaattagac attggcagaa aattaaatac aaataagtat ctataaggct
    16081 atattaaaat attattaatt ttttatttta atatagcctt aaattgttat caataagtga
    16141 aaaatattgt aacaatagaa gaacaatagt attatgttta tagacaaaaa acttattagg
    16201 aggtaaattt atgccaacaa taacattaaa aaatggtgta gacgtactta ttagagaagg
    16261 agtaagggaa gatgctcaaa gcattataga tttttataat gaagtgggtg gagaaactca
    16321 ttttctgtca tttggaaagg atgaatataa aatatctttg gaggaacaag aaaatgctat
    16381 agaatcagca aaagcatccg ataattctgt taaactgatt gcatttatag atggtgaaat
    16441 agttgggatt gcaacgattg attctaatca aaaagcaaaa ggaaagcatg ttggagtatt
    16501 aggaattgtt gtaaaagaaa aatattgggg aattggattg ggtaaaaggc ttatgttaga
    16561 ccttatagaa tggtgtaaat caaatggaat aaccaagaag ataactcttg tcactaatga
    16621 agaaaattat aatgctatag gattatacaa aaaagttgga tttgaagtag aaagcatact
    16681 aaagaaagaa tgttattata atggtgttta tactgattta ataggaatgt cacttttatt
    16741 gggaatataa ttagtgtaca ttttatctcg aaaaaagtat attaagtatg gtataattaa
    16801 aaaagaatat aacttaatat aattttggag gacgaattat gaaaaatctg tgtaaaatat
    16861 cagatgatta tttaaacagc aagcttaagt atttaaagtt attatcaaaa caatatccaa
    16921 gtatatcaaa agcaagtaca gaaataataa atttagaggc tatattaaat cttccaaagg
    16981 gaacagagca ttttataaca gatgtacatg gtgaatatga accatttgta catgtattaa
    17041 aaaatggttc tggtgtaata aagagaaaaa tagaagaatt gttttcaaat acaataagag
    17101 acagcgaaaa aaaaatgtta gcaactcttg tatattatcc tgaacaaaag ttagacctaa
    17161 taattaagca agaggaaaat atagatgatt tttatagaat aaatatttat agacttatag
    17221 aactttgtaa atatgcttct agcaaatata ctaggtctaa agttagaaaa ctgttaccag
    17281 aaaattttaa atacataata gaagaacttt tgcatgagca tgttaaaagt gaacataaag
    17341 aagagtacta taaaagtata gttgaaacaa tagttgacat aggaatagct aaggagttta
    17401 taattgctat ttctacagtt atacaaaaat tggttgtaga tagacttcat gtaataggag
    17461 atatttatga tagaggtcca agaccagata taattgtcga taagcttatt gaacatcatt
    17521 gtgtagatat tcaatgggga aatcatgata tattgtggat gggtgcagcc tcaggtgaaa
    17581 aaacttgtat agcaaatgca ctgaggatat cagctagata tgcgaattta gacattgtag
    17641 aagacatata tggaataaat ctgttgcctt tggccacttt tgctatagaa atgtataaag
    17701 atgacccttg taaagaattt attccaaagg ttaatgacca aagtgtaaca acaacagaaa
    17761 agtctttaat ggcaaaaatg cacaaagcaa taagtataat tcaatttaag cttgaaggtg
    17821 aggttatcag acgaagacct gaatttgaaa tggaacatag actcttgctt aatatgataa
    17881 actatgatga aggtacgatt aatttaaaag gtaaaacata taaattaaaa gatacttatt
    17941 tacctacaat agacaaaaaa gacccatata aattaactat ggaagaaaga aatgttattg
    18001 ataaattagt atcttcattt agaggtagtg aaaaattaca aaaacatgtt tcatttttgt
    18061 tttctaaagg aagtatatat ttaaaggcta actcaaattt actgattcat ggatgtgtac
    18121 cgttaaatga agatggaagc tttatgtcta tgaatataat gggaaaagag tataaaggta
    18181 aggctcttat ggataagatg gagtctctag caagagaagg atttttcttt aaagataagg
    18241 cagaagaaaa actgtatggc atggatatta tgtggtattt atggactggg aaatgttcat
    18301 cattatttgg taaagatgat atgactacat ttgaaagata ctttatagct gaaaaagaga
    18361 ctcataaaga aaataagaac ccatatttta aacttagaga aaatgagatg gcttgtaaaa
    18421 gattatttga agaatttgat ttagaacttg atgaatctca tataataaat ggtcatgttc
    18481 ctgtggagag taaaaatgga gagagcccaa taaaagctaa tggtaaaatt ctcgttatag
    18541 atggtggttt ttctagggct taccaaaaaa ctactggtat agctggatac actttgatat
    18601 acaattctag aactttgcaa ttagtatcgc atgaaccatt taattctgct gaagaagcca
    18661 ttgcaaatga aagtgatatc ttatcgacaa ctgttgtagt agagcataag gcaaagagaa
    18721 aaatggtgag agatactgat gaaggagtaa agatacaaga ggaaatagaa gatttaaaac
    18781 tacttttaat ggcgtataag aaagggctaa taaaagaaat gtagatgtta tagaggcact
    18841 tcatgattga agtgtctttt tgttaatact tattaaatat attataaaga ttaataatag
    18901 tagtttatat tatacttact aagtgaatcc aagataaatg ggttcacttt ttttatttat
    18961 aaacattatt aaaaaaatat agatgttttg gttatattcc ttgtccttta taaatagaat
    19021 tatataaaca aaggaggagg acaagagatg aataaacttt ctgatgaaat aataaactct
    19081 ctttctacaa ctataagaga aaaggtagaa aaagtctcaa acaataatct gaacatagaa
    19141 gaaattaggt tacgctcaca aaaaccattg atactaaatg caaactctaa agattatttt
    19201 tacaatcaaa aaactatgac acttgattta aatcaacaaa actcatatgt agtaacaaga
    19261 gaagatgtag agcaaacttt tcaaataata tgtaaatatt caatacattc atttatggat
    19321 gacataaaaa aaggattcat aactttgaga ggaggtcata gagtagggtt agttggaaaa
    19381 gcaatagtag aagatggaca agtcaaaaat ataaagcata tatcatcttt aaatataagg
    19441 gtatcaaggg aaattattgg atgctcggat aagattttaa gtcatatcat aaagggaaaa
    19501 aatcagatta ataatacttt gataatatca ccacctcaat gtggaaaaac aactttaata
    19561 agagatatag taagaaattt aagtaatggt aatgaagatt atggatttaa aggtttaaaa
    19621 gtggctttag tagatgagcg taatgagata gcaggagctt atctaggtgt tccacaaatg
    19681 gatgtgggaa taaggactga tataatagaa acttgcccaa aagacttggg tattacaatg
    19741 cttttaaggt ctatgtcacc aaatgttatt gtgacagatg aaattggaag tgaaaaagaa
    19801 ataaaggcat tatacacagc attaaatgga ggtataggat taataactac tgtgcatgga
    19861 gattcaatag aggatataca aaatagaaaa gaattaaata gacttctgga taaagagtta
    19921 tttaaaaagg ttataattct ttctgcaaaa agaggagcag gaacaattga aaaaatttat
    19981 gatttagaag aaaagagatg gtattttgca aattaaaata attattatag ctttcttgat
    20041 aggaagtagt tatttgatag gtgaacaaat atacaaaact tatactcgta gacataaaca
    20101 attaaacgat ttaataagag ttttagaaat tttgaggatg gatttatctt ttggacttta
    20161 tacattagaa gaaatcttta ataggatagg tggaaataaa gagttttgtt tttggaaatt
    20221 tttctatcaa atatcagaag gacttcacaa tgagcaaagt aaaactttgg aaataataat
    20281 atcagaaaat attgatgtct taagtaaaga aacttatcta ggcaataaag aaattgagga
    20341 actgaaaaat ctaatactta ctttagggaa aagcgatata gagtcacaac aaagaatgat
    20401 agatttatct atagaaaatt tgaaaaaaca aacctatgag acaaaggaag atataaacaa
    20461 aaaaggcgta ttgtataaaa aattagtgac attcataggt ataggtatat gtattatatt
    20521 gatttaatat ggggaggttt attatggaaa tatcattgat attaaaggtt gcaggtgtcg
    20581 gtattctaat atcagtattg aatatgatat tggaaaaaac agatagaaaa gattgggcag
    20641 gtcttactac attagcaggt gtaataatcg tattgggtat ggtaataaca gaaataagtg
    20701 acttgtttaa tactgtaaga acaatgtttc aactttacta aagaggaggg agtaatttgg
    20761 aaataatgca attaatagga attgcaatca tttcaactac actctgttta gtaattaaaa
    20821 aagatagacc agagatagca aatttcatag ctataataac tggagtaata atactattgt
    20881 cagttatgtt taagctaaat tttatagtag atagtataca agatttggct aacaaggcta
    20941 acatcccgac tatgtatata tcattaataa taaaattaat tgggatagca tacttaatgg
    21001 aatttgcgat acaactttgt aaagattgtg gggaaggaaa cattgcttca aaactagaat
    21061 ttggaggtaa aataatagtt atgtcaatgt ctttccctat acttttgtcc attgtagaaa
    21121 tggtggtgaa tataattcca tagatgtgta tcttggaatg aatataagta tattagagag
    21181 ctttcgttgt attgaggttt atagagtgaa gagaggcatg gttgcttatg aaaaaaagat
    21241 ttttaccaat gattataggt tttttattta ctttcttttt tgtaaatatc tttgctatta
    21301 tgatatttgc taatgaagta ccaagtagtg aagataaaga atatggtgaa acaaaaaata
    21361 gcatagataa gtatatagat ggtcaattag acaagctaga tataaatgag attcaagact
    21421 atataaataa agaaatagtt attaatgatg ttaatttaaa atcatttgta aaagatttaa
    21481 ttagtggaga aaaaaatatc ttagatttat tcaataaaga tggattgaag atattgatgt
    21541 ttgatgaatt taaagcaagt ttaaaggtag tagcagtaat tttggtactg gctctgctat
    21601 catctatttt aaagagtctg gaaaactctt tttcatcagg tgcagtaagt caaatagcaa
    21661 catatataat atttatcaca atggtatcac ttacacttat tggttttaaa gatgtattac
    21721 agatttgcta tgatgcaata gaccatactg taggtcttat gcaagttata atgccaatat
    21781 taataacatt tttactttta attggattcc caataacgtc gactactttg aatcctatct
    21841 tcataggagg agtaacattt ataaatgtat tttttaaaaa ttttctattt gtatctatta
    21901 ctgttgcatt tggaatttta ataataaaca atttatcaaa aaatataagg ttaaagagat
    21961 ttttctcctt tgtaaaacaa ataaattatg tttctattgg agctatgttt actgtttact
    22021 taggtcttgt atccatacaa ggactgtatg taaccagttt tgataaattc agtgtgaaga
    22081 ctgctaaatt tgctataggt aattttattc ctgttgtagg tggatttgta tctgactctg
    22141 tggatatttt attatcttca tctcagctta taaaaaatat atttggagga atagggctta
    22201 tcttacttgt tggaatttgc ttacttccag taataaaaat tttatcagta atagtagtgt
    22261 acaaattagc agcaataatt gtagaacctg ttggagagga tggaatatct aattttttaa
    22321 atgaagtggc aaatttaatg ataataatgc tagcatcagt aattgctata acagtaatgt
    22381 tctttgtaac tgtagctatc ttgacctcga taagtgtcgt aagtcaaggg taatttatat
    22441 atcagtgaaa aataattaca tttaatctaa tatttttaga gaggaggatg ctatgttaga
    22501 gggcataaag gcatggatag ttagtgtttt gataggagca tttatagtaa atatagtaga
    22561 tatgatttta ccaagttcta agataaaacc ttatgtcaac ctagttttaa actttatgtt
    22621 tgtatttatt gtaataactc cagtagtagg atttttttca aaagatatga gtttagaaga
    22681 tagaatatta aaatctatgg gaaactacaa caagcagtat gtagatagta caaatgcttt
    22741 ggcaaaagag actggaaata atagtctatc caagggatat gaggatgggt taaaagaagt
    22801 acttaaatta aaacttgatg aatatggtta tgatttagaa gatatagagc ttaatggggc
    22861 aaatataaat aatataaaaa taaaagaaaa gaataatagt gcaaaaagta ataacagttc
    22921 caatgaagaa aataaaaata atagtactaa aagagaggaa gaaaacataa actctaatga
    22981 caaagaaaat tctaaacaag tcttcaaaaa aggtacagag tatgggttga acctaaatga
    23041 agaaaaatta aaaaacgact taataaaggt gctggatgtt tctatagaag atatacaaat
    23101 tgataaatag gagttgggag aatgttgaaa aacttaaatg acaaagataa gagaaaggta
    23161 tattcactaa taactatagc aggaatatgt gtggtttcat tagtattatt atcttgtttt
    23221 cctagtagca aaagtgataa acaagttgga aaaacagaaa ctaataaaaa tgctgaaaag
    23281 caagtcacta aagaacaaga aaaagatgat ttagagtcaa aattaacagc aatactatct
    23341 aaaattgatg gtgcaggaga cgttgatgta atggttacat ttgaatcaag tgaagaaata
    23401 caacctgctt ttaattcaaa taatacaaca gaaacaacag aggaaaaaga tgcacaaggt
    23461 ggagaaagaa cagttacgac ttctagtgaa aataaaacaa tgataacttc aaattcaagt
    23521 gaccctgtag ttataaaaac tacagagcca aagataaagg gagtgatagt ggtagcaagt
    23581 ggagcaagtg acccaagtgt taaagagaca ctttatagtg cagtacaaac atcattacaa
    23641 gtagctggtc atcaagtaga aatatattct aaataaatac atataaccgg ggggataaat
    23701 gaatgaagtt taattataag ggaagaggat ttgtaataat aactttaact gcaatgttag
    23761 tggtagtagg aacagtgaat tatcaactaa gtaagaaatc tttattagaa acatcaaaag
    23821 agtttaaggc atatgaagaa gcacagttgc aaaaaaatac tgatgatagt gatagtagta
    23881 agacagagga ttctagtaat gtagataaac aaggtggtaa ggaaagtgct gatattgata
    23941 tagtcgatag caaagctagt aaagtaaaag aaaaggcaac tgagacaagt aaggaaataa
    24001 aagctcaatt atcatcagag aaaaatatga aaaaggcatc ttatatttta gatatgaaaa
    24061 tgaatagaga aaaacaaaga aatgagttag ttcaagattt aaatgaaatg ataaataatc
    24121 catctacaac agaagaatct agaaaagaag cttctaatat gaaattaaat atagttaaaa
    24181 ttcaagaaaa agaacttcaa atagaaaacc ttttgagtac aaaaggatat gaagaagcgt
    24241 tagtttatat aagcgataac aaagttaatg tagttgtaaa tgaagctaaa ttagaaaaga
    24301 aagatgcagc aaaaatattt gatttagttg cagaacaagc caatgtgaag tatgaaaata
    24361 ttaaacttac aaataataat agtaataagt aaagtataaa cctcagaatt aactgaggtt
    24421 attttcttgc aaagtagact tgtatttggt attattatac ttataaaaat agttccttaa
    24481 aatcaggagg taagttttaa tatggaagat aataaatttg gacaagtaaa aatatctaat
    24541 gatgtaatag ctacaatagc tggtttagca gcattagaag ttgaaggcat agaaactaca
    24601 gcaacattaa cagataagtt gttaaaaaat aatggagtaa aaatacaaat cgaagaagag
    24661 gatgttaatt tagatgtaat ggttacgata aagtatggaa tgtcaatacc agatacagct
    24721 tttaaagttc aagaaaatgt aaaaaatact gttgagacaa tgacaggact gaaggtttct
    24781 caagtaaata tacacattca aggaatcagc tttaagaagg ataaagttga taaagaagaa
    24841 gcaaaagcaa ctaagaaaaa ttaatattag ccctctgaaa agtcagaggg ttttttgctg
    24901 gtaattgatt ttatatggat aattaaactt aaaggagaat tttgattgat gaaaaaagat
    24961 agggcacaaa agagtacaac aagagaatat ataatgaaac ttatatacca aataaatatt
    25021 aataaagaag attttgaaac tttagaagat aaagtagata attttttaaa agataattca
    25081 gaacatatta taaatagata taaagaactt gcacttcaat actcaaaaaa tacaaattta
    25141 aagttagaag atactgaaat tgaagatgtt atagacaaaa aatatataaa tacagtatgc
    25201 aaagcattga aagaaaatca tgacaaaata gatgagttaa taaataagca tgctaaaaac
    25261 tggacagtag atagaatgcc aaaggtagat gtttctatac ttagattgtc tgtgtgtgaa
    25321 atactttatt tagacactcc taataaagta tcaataaatg aagcagtaga acttgcaaaa
    25381 atatattgtg atgataagtc tcctaaattt ataaatggta tattgggaag tgttgttgat
    25441 gaaattggga aataatataa taattggaat tgatactagc tgctatacta cttctatagc
    25501 agctatctct ttagataaga aagttatatt caatgaaaaa ataatgttag aagtaaggga
    25561 taattcaaaa ggtttaaggc aaagtgaagc tgtatttcaa catatcaata atttagggat
    25621 tcttagtgat aggataaaat cttttaaaga taagtttaat gtagaaggag tttgctcatc
    25681 aaaaaaaccg agacctgttg aaaactcata tatgcctgta ttcaatgtag gtcataattt
    25741 tggaaaatta ttgtctagta tatatggttg taggttttat gagactactc atcaagagaa
    25801 tcatattgaa gcaagtttat taaatagtaa attaaaaaat aataataaat ttatttctgt
    25861 tcatatgtct ggtggtacta cagagatact tttaacaagc aaacaagata gtcatcacaa
    25921 tgtatgtgat actaatttag gtaaaattgc caaaataagt attaaaaaag atgataaaag
    25981 taagttatac aataattttg gatataatat agatataatt ggaggaagta aagatattag
    26041 ctttggtcaa cttatagata gagtaggaat taagcttgga tataaatttc cttcaggaaa
    26101 gtatttggat gaaaatgctt taaattgtaa tcttaaaata gaaagtggtc tgaaaacttc
    26161 tgtaagagat ggatatatga atttatcagg attagaaaat caggtaaata agattataaa
    26221 tgataatgga gataatacta atcaaaaaga atatatatct aaattagtat tagattcagt
    26281 agttagaaat atgtttaaat ctttagttta tttatgtgaa acttataatg taaatgaagt
    26341 agtatttgct ggtggagttt ctgcaagtaa gtatattctt agagaattaa gcatgaagtt
    26401 aagaaaaaag catatagaag cttattttac agaaccacaa tattcaactg ataatgctgt
    26461 cgggtgtgct ataataggat tgaataactt tttaggagaa agagtatgaa actaagagct
    26521 ttagatataa gtgaagcaaa ctcatatatt aaaagaattt taataaacga cccaatactt
    26581 tctaatctta aagttaaagg agaaatttct aattttaagg ttcatagtag tgggaatgta
    26641 tatttatcac ttaaagatga aacatcaaag ttaaactgtg taatttttaa aagtaatttt
    26701 aatcgcaatt taaaattaga taatggtgta aaaattatag ctaatggata tatatcagtc
    26761 tatgaaagag atggtgcgta tcaattatac attaatgaaa ttgaaataga gggaatagga
    26821 aatttacaca tagagtttaa tagattaaag gaaaaactta ataaagaagg attatttgac
    26881 cctaaataca agatacctat acctaaaatg ccaaactcaa ttggcgttat aacatctcca
    26941 acaggtgctg ttataagaga tataataaat gtaataaaaa gaagataccc gaaagttaat
    27001 ataaagcttt atccagtaac ggttcaagga gataaatcag ctgaaaaaat ctgtgaagca
    27061 attagatttt tcaatcatat gaagaatgtt gatacactta tagttggtag aggtggaggt
    27121 tcaatagaag aactttggtc ttttaatgat gaaatggtag caagagaggt ttttaattct
    27181 caaattccga taatatcagc agttgggcat gaaacggatt ttactatttg tgactttgtg
    27241 tctgatatga gagccccaac gccatcagca gcagctgaga ttgctactcc atcattggat
    27301 gatataaact ataaacttgg aaacataaaa agtaggatga gtaagtctct tacaaatcaa
    27361 atagagctag accaatatag gttagaaaca gtatttaata agataaataa ctatttagat
    27421 tcgtacacaa taaaagataa agttatacaa ttagacaaaa tatatgataa aataattttt
    27481 ggaatagaaa ataatttaaa attagaagat gaaaaattag taaaaattgg agcattactc
    27541 cataatttaa gtccattagc tactatggat agaggttata gtataactca aaaaaatgga
    27601 aaagtaataa atagtataaa aggattaaaa ataaaggata gtatagatat agtattaaaa
    27661 gatggaaatt tagaatgtat gatagataaa attgaaaata aagagggata gtatgaattt
    27721 aacctacgaa gaagcttata aaagattaga aagtatttta agtgaattag aatctaaaaa
    27781 tgctagcttg gatgaatctt taagcctata tgaagaaggt ataagccttt ataaacattg
    27841 taataagctt ttagatgatg ctaaattgaa aataagtaaa tttaatcaat tgggaataga
    27901 agaagacttt aaaatagagg aggaataaaa ttggaattta aacaatgtct aaaagaaaaa
    27961 gcaagttttg tagaaaaagt acttaaagaa tatatgccta aagaagaagg gtatcaaaaa
    28021 actgttattg aagctatgaa ctatagctta agtgctggag gtaaaagatt aagaccaata
    28081 cttacattgg aggcttgtaa aatagttgga ggtaatgaag atgaagctat tccttttgct
    28141 attgcaattg aaatgataca tacatattca ctaatacatg atgatttgcc agctcttgac
    28201 aatgatgatt taagaagagg aagaccaaca aatcataaag tatatggaga agctatgggg
    28261 attttagcag gagatgcttt gttaaactat gcttttgaag taatgcttgc aggctcaatc
    28321 aataaagaaa atccagaaaa gtatctaaaa gctataaatg aaattgccaa aggtgctggt
    28381 atatatggaa tgataggtgg tcaagtagta gatgtagaaa gcgaaaataa acaaattgaa
    28441 aaagaaaaat tagattatat acatatgaat aaaactgctg caatgatggt aggctgtatg
    28501 agagcaggag ctactatagg tggagcaaat tctgaacaaa tggaagaaat aactaaatat
    28561 gcaaaaaata tcggattatc attccagata gtagatgata tactagacat agtaggagat
    28621 gaagctaagt taggtaaaaa ggttggaagt gatatagaaa atcataagtc aacataccca
    28681 tctcttttag gtttagataa atctaaagaa attgcacata atttgattga tgaagcaaag
    28741 aagagtatag aaaaattatc tgatgatgta gattttttaa agggattggc tgaatatata
    28801 atagatagag aatactaaaa tatacagcta aaatcgagga gggaaaaatg gatttttttt
    28861 cggagatttt taacaatggg gctttgggaa taagtctgat tgcttgtttc ttagcacaat
    28921 ttataaaaat atttactggt aaggaaaaaa gaattgagtt atcaagaata cttatttcag
    28981 gaggtatgcc tagttcccat agttcttttg ttacaagttt agctacagtg gtaggtattg
    29041 aaaaagggtt taattctact gattttgcta taattaccgt gcttgcctta attataatgt
    29101 atgatgcagc aggtgttaga cgggctgttg gtaaacaagc tactatatta aatcaaatgg
    29161 tggcagatat acagcatgga aagcatatag agcagaagaa attaaaagaa ttaataggtc
    29221 atacaccact agaagtttgg tttggagctt tacttggaat agtaacagct ttaatattga
    29281 tgtaaattga aaatttacag aataaaggtg aggataatat gtataaatat ttagataaag
    29341 taaattctcc aaaggatata aaaaatatga gtatagaaga aatggattta cttgcaaagg
    29401 atataagaaa gttcttagta aaatctgttt caaagacagg aggacactta gcttctaatc
    29461 taggagtggt tgagttaaca ttagcacttc ataaagtatt tgatagtcct aaagataaga
    29521 ttgtatggga tgtagggcat caatcttatg ttcataaaat agttactgga agaaaagatt
    29581 gttttgtatc tttgagacag tttaatggac taagtggttt tccaaaggag aatgaaagtc
    29641 ctcatgatat ttttgataca ggacatagca gtacatctat ttctatagct acaggtattg
    29701 cctgtgctag ggatataaaa aaagaaaact atagtgttat atctgtgata ggagatggtt
    29761 ctataacagg aggtatggca cttgaagctt taaatcaatt aggatatata gataccaata
    29821 tgatagtaat ccttaatgat aatgagatgt ccatagataa aaatgttgga ggaatgtcta
    29881 aatatctgtc aagtattata agaaactcaa cagttgagaa aatgacagat gaagttgata
    29941 aaattttaaa tgttacacaa acaggtgaaa ttttatctaa gactgcacat agatttaaag
    30001 ataaactaat gtatagcttt tctcctcagg actgttcatt ttttgattca ttaggtataa
    30061 gatattatgg acctatagat ggccataata ctaaagaact aatagatata ttgagaaaag
    30121 ttaaacacaa aaaagggcct gttcttttac atgtaattac gaaaaaagga aaagggtaca
    30181 gatttgcaga agaacaacct gataaatatc atggagtatc aaagtttgat ataaagacag
    30241 gtgttacatc tgcaaaagtt aagtctatgt caattagtgt tggagaaaaa cttgttgata
    30301 tggctaatag taatgaaaat atagtagcaa taacagctgc aatgccatct ggtacagggt
    30361 taaacctgtt tgaaagtgca tatccaaaaa gatattatga tgttggtata gctgaacaac
    30421 atgcaacagg atttgcagca ggtcttgcaa aaaatggtat gaaaccttac tttgctgtgt
    30481 actcatcatt tttgcaaagg gcatatgacc aagttattca tgatgtatgc ataacaaaaa
    30541 agccagttac ttttcttata gatagagctg gattagttgg aaatgatgga gaaactcatc
    30601 atggtatgtt tgatttaagt tacttgaatt ctattccaaa tattgtagta atggctccaa
    30661 aagacacaag agagatggag cttatgatgg atttgtcatt aaaattagat tgtccactag
    30721 caattagata cccaagagga agtagttatt acctagataa gggagagtat ggagagattg
    30781 tactgggtaa atatgaggta ttagatgagg gtcaagatac agtcatactt tgtattggaa
    30841 gtatggtaaa acatgcttta gaggctaaag aaatattatc aagagaagga ataaatccga
    30901 caatagttaa tgctagattc ttaaagccaa ttgatgaagg tatgttaaaa gtattattaa
    30961 aaaatcataa aaatgtagtt actatagagg ataatattgt aactggagga tttggaagta
    31021 gaataaataa gtttattata gataatgaat ataacgtaaa tatacttaat atagcaatac
    31081 cagaagaatt tgtaaaacat ggcaatatag atgaattata tgattttgta ggattatcgc
    31141 caaaaagtat tgctgataaa ataaggaaat tagttattga gtaaaaatct aatgtagata
    31201 ttgtaaatta aaatttatat aaaatataga atttatcaat tagaataaat atcaagtgtg
    31261 ttacttcaag ctactttagt tatcatcatt aaagtagctt ttaacagaaa ggtaattgta
    31321 tgaaaaaaag aatagattta ttattagtag aacaagggta ctttgaaagt agagaaagag
    31381 ccaaaaaagc aataatggct ggattggttt ttgttgataa tcaaaggtgt gataaggctg
    31441 gtacagaagt aaaagaagat tgtagtatag aagtaaaagg aaatccaata ccatatgtca
    31501 gtagaggtgg tttaaaactt gaaaaagcaa tgaaaaactt tgacttgact attgatggaa
    31561 aggtatgtat ggatataggg gcatccacag gtggttttac agattgtatg ctcaaaaatg
    31621 gagcaataaa agtattttct atagatgttg gttatggtca acttgcatgg aaattgagac
    31681 aagatgatag ggttgtgtgt atggaaagaa ccaatataag aaatgtgaca atagaagata
    31741 caaagcagtt tgctgatttt gcgtcaattg atgtgtcttt tatatcgtta aagttagtac
    31801 ttccaaaggc aaaggagtta gtacgtcatg atggggaagt tgtcgcttta attaaacctc
    31861 aatttgaagc aggaagagaa aaagtaggta aaaaaggagt agttagagaa aaatctacac
    31921 atatagaagt tataaaaatg atttctgatt tctcagtcga aaatggattt gagattttag
    31981 ggttagattt ttctcctatt aaaggtcctg aaggtaatat agaatatcta attcatttga
    32041 gaaatggaaa tgaaggatat gaatttgatg gtgagacata caataacaaa atagtagaag
    32101 ttgttgaagc ttctcataat ttagacaaat aggttaaaag ggggcttaga tttgatcctc
    32161 gaattatata tgaaaaattg tgccttagtt gaagaactaa ggttgaatat tgataaaaac
    32221 ttaaatatac ttacaggtga aactggttca ggaaaatcta taataataga tgcacttgga
    32281 ctttgtttag gtgataaata tgataggtct tttttaagaa aaggaacaga taagggactt
    32341 gttgaggctg tatttttttc agacaataga tatcttaaaa aaatattaga agaaaatgat
    32401 ataagtatgg aagatgataa tttattggta ataactaggc tgatatactc agatggtaag
    32461 agtactgcta gagtaaatgg aaggactgtt aaagtgtctc ttcttaaaga aattgcatct
    32521 acacttatag atatacatgg tcaacatcaa aatcaagctt tgtttaataa agatactcat
    32581 ttaaaatttc tagacctttt tggagaaaat gaattggaag agtttaaaat tgcttataaa
    32641 aaggtgtacc ataagtatag tgaagtaaaa aaagctttaa attgcttgac agaaaataaa
    32701 gatgagatgc aaattcaacg agaaatagat ttattaagat ttcaaataaa tgaaattgaa
    32761 tctgcaaatc taaataagaa tgaatatgaa gatttattaa aacaaagaga agtttataga
    32821 aatagtgaaa agatatataa taatctaaat tcgagttata gcaagttaca taatggtgag
    32881 tataatgtta ttgacctaat aggtcttgca tctaaggaac ttaatgacat atctaaatat
    32941 gacagtgttt taagtgaata tagtgatact gtagaaagaa tcatgtatga gttacaagac
    33001 atatctggtg agataagaaa ttacaaagat aatatagact ttgaacctta tgagctagag
    33061 cagattgagc ttagaatcga cgagattaat aacttaagaa gaaaatatgg agacagtata
    33121 gatgatatat ttgagtatta tggaaaaatt aaagatagat tagatgaaat attaaacaga
    33181 gatgaaagag ttgaacagtt aagaagcaaa ctgatgaata tagaagaaga tttaaaaata
    33241 aaagccagta aattgactaa agcaagaata gaagtagcaa ctactttaga aaaaatactt
    33301 cttgatgaat taaaaagctt aaatatgaaa aatgtaatgt tcaaggttaa ttttgaaaaa
    33361 ggtccattta ctttagatgg agtagatgat attgaattta tgatatcttt taacttagga
    33421 gaagatatta agcctatata taaagttgca tcaggtggtg agatgtccag atttatgtta
    33481 gcgtttaaaa ccatattggc tgatatagat gatattgata cattagtgtt tgacgagata
    33541 gatactggaa taagtgggat agcagcacag atagttggtg agaaattgag tgatatagca
    33601 aagaaaaaac agataatatg tataactcat ttacctcaaa ttgctgcaaa tgcagacact
    33661 cattattgta tagagaaaga tacttcaaat aataggacgt ttaccaatgt tagtaagtta
    33721 aatgaatccc aacgaaaaaa tgaaattgcc agacttatag caggtaataa tataacagaa
    33781 aaaactattg aacatgcaag tgaaatcatt gaattggcta aaaaatgtta gtgaaaaaca
    33841 agcattttaa taggtgtaaa gaatttttat agaaatgctt tacacctatt ttttataatg
    33901 aaattatttt aaaatatcta gtgcctatat tgaagaaaag taggtttgaa aatggaatga
    33961 actttgtata aatttgtaac tttgaaattt ctaaatgctt aagtataata ttatttatta
    34021 aggtagtagt gaggggaggc ataaaatgaa taaaaaagat actatgcact taatttttac
    34081 aattgtaatt tttattttat tatggtatat tgtggtagca gtaagtgaga ttaataaaaa
    34141 tattgaaagt tgtagtaaca aattagatta tttgtcacaa gagcttatga gtactaagtc
    34201 ggatattagt aatactataa atgaagaaat gtcaaaaagc tatataacaa aaagtattga
    34261 cttaaaagtg aaaaaaatcg agaaaaaaga atgtattatt gatatagatg ttcaattaag
    34321 taaacttgga aaaaatggaa aagtattttt tatgtataaa gaagatagtg ataaatggaa
    34381 tgaaactgag atgacaaaac atggagaatt atcatatgca tgtgaaatta agataaatac
    34441 aggaagtgaa tatgactata aagtagttac aagtggagct atatctgaaa gttctgatgt
    34501 gcaaaaattg actaaatctg attatatgcc tgaacaaccc atatttactt ctgggataag
    34561 agataataga gaatacttta ttgaaatagt agaaaatagt aatcttttca atcatgagag
    34621 tgaaaagtca aaaaataaag tttatgataa tattagatta gaaaaagtag atattattgt
    34681 aaatgaagga aaaaaagaca ctatatacaa agccaaatta gctgaaggct tagatgatgg
    34741 caaaattaat aattcaaata gaaatcaagt gaattatgaa gtaagttttc ctaaaaggga
    34801 tattgatgac ataatttata ttaaagctaa acttacatac aataatggag tagaatatac
    34861 aaaggatata actgaagata taactatggg attacaagat ttagaaaaat aaatacatat
    34921 ttaaataaat attcaaatag attttttcaa taaaatagag tataaataaa actgtagtag
    34981 ttttacttat actctattaa aaaattataa ttttaattcc atatatctag ccccttcaat
    35041 tggattataa gtataaggtt ctatatcata aaaaccaaac ttttcatata atccttgtgc
    35101 acttttcatg cttggaagag tatctaatct catgtgtgta tatccaaatt ttttagcttc
    35161 ttcaatgatt tcttccaata gtatttttcc tatttttaat cctctaaatt gatttcttac
    35221 atataatctt tttaattcac atattttacc ttcaagtttt tttaaagcaa cacaacctgc
    35281 caaattttca tcaacaaatg ccaatatcaa tgagcctgaa ggttttttat attttcctgg
    35341 aagtgttttt aattcattat taaagtcttg aaaacataag tctatattta gagaatttga
    35401 atattcagta aatagaagtt ttacgttttc aaggttttct aaatcttttt cttcaacaaa
    35461 ttgtaaagtt atattttgag ccattttatc cgccattata tacacatgtt tatataatga
    35521 cttcacctcc ttgatatatg tatatttttc ttaatatcaa ttagatttta ataccattac
    35581 tttttcacca ccatagtcaa gctctccatt aaactcaaat ccaaaatctt tataaagctt
    35641 aatagccatt ttattgtctt cgaatatact aagatatagt tcatcacagt tatattcatt
    35701 tttaagatga tttacaagaa aatctaatga tgcttttcca tatcctttac cttgatattt
    35761 tgaatcaatc ataaatctat caagccaaac tctatcatct tctaaacgac catacatagc
    35821 aaatcctatt aaagaatttt catcatatat tccaacaggt acccaagctg ttataaattt
    35881 agattcagca atagaaagtg cattgctttc tatataatct aactgacttt tatctacaga
    35941 caaactaact aaatcacgcc aattatttat gtctgcaatt ctcacattta atttcaagat
    36001 attaccgccc ttcaaacttt ttgttacaat ctaatactat catattatgt attaaaaatc
    36061 acttattaag attttaaata aactttttaa atgaataaat tctcaggaaa aaggaattat
    36121 aaatacataa taatacagca taggagtaga tggatatatg aacaaaataa ataaaaattt
    36181 caaaaatatt tggataatat taggagctgt atcgattttt accatggtta taatttttaa
    36241 taaaaattgt aatgttaata aagagactca aatagaagct tttacaatta agaatcatga
    36301 taaaaaattt gtatatccta tgggaaatat aattggagta aaagcaaata cagatggtgt
    36361 attggtctta ggatatgagg aagaggatgt agactatatt ggaggcatac aaatcggtga
    36421 taatatagta aaaatagata ataaaaggat aaaaaatagt caagatgtat cagagatttt
    36481 gaataagatt aaaaaaagta aagttgaagt gacttttgag agaaaaaata agtataaaac
    36541 agaagtaata gagactaaaa aagaaaatgg caagtataaa cttggattat gggtaagaga
    36601 taaaatatct ggaattggaa ctatgacttt ttacgaccct agtatggaaa agttcaaagc
    36661 aattggtcat gccataaaag attcggatac taatgaacta ttaaagataa agcaaggata
    36721 tatatataag ccagaacaat taaaaatagt aaaagctagt aatgaaaaag taggtaaaat
    36781 aaaaggagat tttaatgaca gcaatttaat gggtaatttc tcaaataatt cagagttagg
    36841 tataagtggt aatattacag aaaaccataa taaagagttt aatgtagcaa ataaagaaaa
    36901 gcaattaata gaagttggaa gaccgcaaga tgtaaaaata ggagatgcag taattctttt
    36961 tgaggataaa aacaaaaata taacaagcta tgatataaaa atagaaagta tagtatatga
    37021 taaaggaaat tatagagata tggtaataaa agtagtagat gacaagttat tggaatacac
    37081 aggaggtatc gtacagggga tgagtggagc tccaataata caaaataata aaattattgg
    37141 tgcaataact catgttttta gagataatcc gaaaaaagga tatggtattt ttatagatga
    37201 aatgataaaa ttgtaggtga ggcattaaaa aattttatta ttttatcaat tatctaggag
    37261 gaatataatt ttggagtgtc gaatatgctt tagagtagat aattaggaag caattgtgta
    37321 aaaagtttag ttttctgtaa taagaagatg ttttttaatg gggggatttt tagtggaaaa
    37381 aatcaaaata gttttagcag atgacaataa ggatttttgt caggtattaa aagagtattt
    37441 gtctaatgaa gatgatatcg atatattagg catagctaag gatggaattg aagcattaga
    37501 cttagtaaaa aagacacaac cggacttatt aatactagat gtaataatgc cacatctaga
    37561 tggattaggt gtaattgaaa aattgaatac tatggatata cctaaaatgc caaaaataat
    37621 agtactatca gcagtaggtc aagataagat aactcaaagc gcaataaatc taggagcaga
    37681 ttactacata gtaaagccat ttgattttgt tgtgtttata aacagaatta gagagctagt
    37741 ttctaataga gttacacaag ttgagccaaa acctagacca gttcaagaga ctcaaatgac
    37801 tagaagtgat tttgttaaga atgtaggaaa tatagagaca gaaatcacaa atataataca
    37861 tgaaatagga gtaccagctc atataaaagg atatttatat ttaagagaag caataaaaat
    37921 ggttattgat aatgttgagc ttttaggtgc agtaacaaaa gagttatatc caagtatagc
    37981 taaaaaattc aatacaacac caagtagagt tgaaagagca ataagacatg caatagaggt
    38041 tgcatggagt agaggaaaag ttgacacaat aaatcaatta tttggatata cggtacacaa
    38101 tactaaagga aaaccaacta attcagaatt tatagcaatg attgctgata aattaagact
    38161 agaacatagt atggttaaat aaacaagaca taaaaagtaa ggctttttaa ttaaggcatt
    38221 ggctataaat gcgtattaca agcagcgaaa cggtataacc actagggtta taccgtttcg
    38281 ctattttaat aaatataaaa attttcttta ttatttgctt actatatcaa tataataatt
    38341 ttattatact atggatatag tatgtgtctt tacaagttgt aaactgacag tggtttattt
    38401 tttaatataa atattgactt tgatgcaggt aaactttgta tttttaagcg tattatggaa
    38461 tatgttaaat aaaaaaatga tgaaatatag tattgtaaat gccaaagatg caaaacaaac
    38521 ttaaaacatt tattttattg ttaagtaatg ctataatata atgtgatttt aataatgata
    38581 gtggaggttt aaatatgaga gtcgaggccc ctataaaagt agatcgaaaa accaaaaaac
    38641 ttgctaaaag agttgaaagt ggggaaatag cagttataaa tcatatagac atagatgaag
    38701 ttgctgcaaa ctctttagta gaagctaaaa taaaacttgt cataaatgcg gctccttcta
    38761 taagtggtag gtatcccaat aaaggtccag ggatattaac tgaaaataat atactaataa
    38821 ttgataatgt tggagaagag ttatttgaag aattaaaaga aggagaaact atagaagttg
    38881 tagatggaaa gatatataga aaaggaaaat ttttaggtgc aggagaagtt ttagacaagt
    38941 atgaggtttc acaccaaata aaggctgcct atgagaattt agctgtagaa ttggatagat
    39001 ttatagataa tactatagat tatgctaaaa aagaaaaagg atttatactt ggagaagtag
    39061 aaattccaaa agtgaaaact aattatgcta ataaacatgt attgatagtt gtaagaggtc
    39121 aggactacaa agaagattta agtactatgc tttcttatat agaagaggta aagccagtat
    39181 tggttggtgt tgatggagga gcagacgctt taattgagtt tggatatact ccagatgtga
    39241 ttgtaggtga tatggatagt gtaagtgatg aagctttaaa aaaggctagt gaaatagtag
    39301 tacatgctta tacagatgga agagcaccag gtcttaagag ggttgaggaa ttaggcttag
    39361 atgcagttgt atttcctgcg ccaggaacta gtgaagatat agctatgctt atcgcttatg
    39421 agtataaggc tgagttaata gtagcagttg gtacacattc aaatatgatt gattttcttg
    39481 aaaaaggaag aaaaggtatg gcaagtactt ttttagttag actaaaaata ggttcaaagc
    39541 ttatagatgc taaaggcgtt aatttgttat acagaagtaa attaaaaata aagtacatat
    39601 gggcattaat agcaacagca ttatttcctg tgttggtagt tgcatcattg tcaccaggag
    39661 ttcaacagtt catacaacta atgcaattaa agtttagagt attattacag atgtaaattt
    39721 taggaggata aatatgcata ttaatatgaa atattatata gtcactatag gggctatatt
    39781 tatagctttg ggtataggca tgttagtagg atttaattta aataataatc aacaattaag
    39841 tgaacaacaa gcaaacataa taaatgattt ggatgataag tttgatatct taaaagaaaa
    39901 aaatgataaa cttgacagtg acttagcaag tgtaaataga gattatgaag aggcagttaa
    39961 ttttataaat aaaaatgtag ataagatttt agctggttcg ctgaatggta agagtatagg
    40021 aataatatct gctaatgaaa atgacgatta tacaaaaaat atagaagaca taataaataa
    40081 atctaatgga agcattgcat ttaatataat attaaaagaa aacataacaa atccagaaaa
    40141 gttaaaggaa atgtcaacta aactaggtac agatgtaaaa aatgcaaatg atgcagttaa
    40201 ttatataatt gacactctta aaaaggaaga tgcaagtgac attttaacat atcttcaaga
    40261 actagatgta ataaagttta attttattgg agatacatat ctaaaatatg attccgttgt
    40321 aatagctggt ggaaatgatg caaaagacag tacaaaacag tttgaaaaaa tagaaaaatt
    40381 tgtagtttca aaacttaaat cagagaataa atatttagta gaagttcaaa atacaggagt
    40441 taaaacttct tatgtagaac tatattctaa aaacaaagtt gcaactatag acaatattga
    40501 tgaaggtata ggaagtatat ctctagcgat tcttctacaa caaggtaata tagttggtaa
    40561 ttttggtaga ttggatactg caacttcatt gttgccatct attaaataga aataatttta
    40621 aggagagaaa aaatggattc ttatataagt ataataatac cagcttataa tgaagaaagt
    40681 agaataaaat atacattaga aagcatattg gacattaagc aaataaatga aataatagtt
    40741 gtggatgatg gttcaattga caatactgct aaggttgtat ctgagctaga aaatgaaaag
    40801 attaaatttt ttaagttaga taaaaataga ggtaaaggat atgctttaaa ttatggtatc
    40861 aaattagcaa tgaaaaatgc agatattata ggttttctgg atggagattt aggaagttct
    40921 gctaaagaag ttgaaaaatt aatagtacct atattaaatg gtgaggcgga tgttacaata
    40981 gccaagtttc ctcctgcaaa gagaaaagga ggtttgggat ttgtaaaagg tttagctaaa
    41041 aattctgtgt ttgagatgac tggtgttgag ttagatgcaa ctttgtcagg tcaaagaata
    41101 tttaaaagag aagttttaga aaagtttgat gaaatacctt ttggatatgg agtagaagtt
    41161 ggaatgacca ttgatatatt aaagtatgga tttaaaatta aagaagtatt agtaaatatg
    41221 actcataatg aaacaggaag aaatttaaaa ggttttattc atagagggaa acagtattat
    41281 cacataaaaa aggttttagg acaaaaaaag aaagaatgga ggtaatatct tagtgaaaga
    41341 ttatatactt tataccattt tattattaac tggattattt ggaacctatg ctgtaattcc
    41401 actatttaaa aatttattga taaatggaaa tgtacttaga ccaaactata aaaaagatat
    41461 gataccagta agtatgggaa ttgtattttt gcctatgatt gtaatcaatg gaataatact
    41521 tgctttcttt actacagaat ttaaggattt agcgtatata tttatgttta tgtttggtat
    41581 gatatccatg ttttttgcag ggatactaga tgatgtcatt ggaaatagag atgtaagtgg
    41641 tttaaagggg cattttaaaa gtttatttaa aggaagtctt acaacaggag gttttaaagc
    41701 tttatttggt ggatttgtag ggcttatagt ttctgttgct atatcaaaag acataattga
    41761 tataatagta aatacactaa taatagctct atcaactaat ttaatgaatc ttttggattt
    41821 aagaccagga agggcaataa aagcatattt attcataatg gtaattatat ttttaacatt
    41881 gacaggattt gttcaagttc ttccattact tatagtacca aatgtacttg catactttaa
    41941 ttatgattta aaagcaaggg ctatgatggg agatactggt tcaaacgtcc ttggaatatc
    42001 tattggaatg ctcatttctt ttgggtatcc atttaacatt agattaggat ggttaatatt
    42061 tgtagttatt atgcatatat tcactgagaa atactcatta actaagataa tagaaaaaaa
    42121 taaactatta aattttatag ataaattggg aaggtagtat tatgataagc aaaagagtgg
    42181 ggattgttga atcaatagta agtcaaactg aaactctaga tgatataaga gtaaatataa
    42241 atggagaaat acaaaaggca tataattatc caaaaatatc tggaactata aatataggtg
    42301 atgaagtggt tttaaataca acagcagtag aactgagctt aggtacaggt ggataccatt
    42361 ttgtaataac taatttaaat aatatagaat ctactttaac tgaaggtgga catataatga
    42421 aacttagata tacgcctctt caaataaaag tggattctgt tgaggaacaa gaaagtattt
    42481 atcatgataa atttgcgaat tttaaaggat tagaaggtct ttctgttgta gtagggactc
    42541 ttcatagtat gttaactcca tttgcagctt catttaaaag aaataatcca aataaaaaat
    42601 tagtgtatat aatgactgac ggagcatctc ttccaattta tttaagtaaa aatgtggata
    42661 ctttaaaaga aaaaaaatta atagatagta caataactat aggaaatgcg tttggtggag
    42721 attatgaatg tataaatata tatactgcat taattacagc aaaagaaata ctaaaagcgg
    42781 atgcagtatt tgtcagtatg ggacctggaa ttgctgggac aggaacaaaa tatggattta
    42841 cagggattga acaaggctct attcttgatg ctgtaaaaaa acttgaagga agagcaattg
    42901 caattccaag aattagtttt gctgacaaac gagaaagaca tcaaggtatt tcacatcata
    42961 gtatgactgt atttaaagaa attgtaaatg taaatgtaga cataccaata actatatatg
    43021 atgatgaaaa attgaacttt ataaaagagc aaatcaattt aaatggttta gacaaaaagc
    43081 ataatataat ttatatagat aataataaaa cgaaagagga tttagactat tttaatctaa
    43141 aagtaaagag tatgggaaga aattatgaac aagatgaggc atttttcaaa gctgcaagca
    43201 cagcagcata ttacttaatg gaggtttaag atggtattag aagaaaaaac tattagtagt
    43261 gatagggttt atacaggtaa agtaattact ttaaaggttg atactgttga aattccaggg
    43321 caaggatatc aaaaaaggga gttagtagaa gttggtggag cagtaggaat agttgcaatc
    43381 acagatgata ataaagttgt gttagttaag caatttagaa aacctataga aaagccaatc
    43441 tttgaaattc cagctggtaa actagaaaaa aatgaaagtc caaaagaatg tgctgaaaga
    43501 gaattaaaag aagaaacagg gtatagtgca aaaaatatta agctaataca taaatttttc
    43561 acttcagcag gtttttctaa tgagataatg tttgtatatt tagcaacagg tcttactcca
    43621 ggagagaata atttagatgc agatgagttt ttagatgtct atgaaattga gcttgaagaa
    43681 gcatataaca tggtattaaa aaatgacgtt gaagatgcaa aaacatctat tggattatta
    43741 ttagtaaaag atatgtttaa aaattaatat ttataaaatg aataaccctt tgtcctaaag
    43801 catattattt tataaaggac aagggggaat taaattgaga agaacatata gaaaaaatga
    43861 ttttagagaa ttaaatagac aaataattat tataggattg ttgtttatga tgtctattgt
    43921 tgttgggtct tacataaata aaatattgcc aggttctagt aacaatatat taaacaatat
    43981 aaatcctgct gtagagtatt ataatctaaa tataagcata aaagatacag tgatacaaaa
    44041 tttaaaatca gatgcaatct ttatgggctc aatagctcta ttaagtctat ttgtagtaac
    44101 aattccagca gtgttggtag cttttgtatt aaaagggatg tcaattggtt atacaataaa
    44161 tagttgtata ttggcattaa aatttaaaag tataaaaatg attttaataa tattatttaa
    44221 aaatttgatt attattccat gtgcaatcat attagcatta attagtttaa gttattttaa
    44281 agaaatggtt tatgaattta aaaagaaaaa tagaaaaaat atgcaatttt taattaagag
    44341 gtatatacta aatattataa ttataatagc actatcattg gggttgcaat taatattaaa
    44401 tactgcaagt attggtatta ttaagttcct agctaaataa aggagtttat aatggatatt
    44461 atagagggat atatagatta cataaaagat aaaaaaaaat tatcagagaa tacagtggca
    44521 tcatacttta tggatataaa aaaatatatg gaatatataa atcaaaaaag cattaaacta
    44581 gtagatatag tagaaaatga tattataagt tacttaataa agttggaaaa agataatgta
    44641 tcaatagcta caatagcgag gatgatatcc tctataaaat cttttcatga ttatttattt
    44701 ttaaatcata tatgtacaaa taatcctgca aaggatataa aaaaacctaa aataaaaaaa
    44761 gaaaatataa atatacttac agaagaagaa attgaaagac tattaaattt tccaaagtta
    44821 acaacgccta aattgattag ggacaaggct atttttgaag tattatatgg tactggtata
    44881 aaagtatctg aattagtaga gatgaatata gaggatattg acctagatat tgattatata
    44941 tattgtaatt catgttgtaa aaatcaaaga gtgataccac tttgtgatat tacaaaactt
    45001 tacttagaaa agtatctaaa agaagcaaga cctaaaatgg ctgtagaagg tgaaaaatca
    45061 ttattcgtaa gttcattagg tcaaaggttt acacgacaag gtctttggaa agtcataaaa
    45121 aaatattcta atctagccaa tatagataaa aatataaatc ctacaatgct tagacattca
    45181 tttgctattc atttgttaaa tgaaggtgct aacattgctg ttgtaagtaa aattttagga
    45241 aatgttaatt tatctagttt gcaagtatat ttaaatcata tagataaaaa cgtgagaaga
    45301 gaaataaagg agaaacatcc tagaaatgat gttgatgtag aattacaaaa agcagaagct
    45361 aaatagacta tatagcaaat tttataattt agaaggagca tatttatatg agcagagtaa
    45421 tttggattgt aattgatagt gttgggatag gagcattacc tgatgctgaa aaatttggtg
    45481 atagtaagga tgtaagtacc cttggaaata tatttaagga atatccagat attcagattc
    45541 ctaatatgag aaatttaggt ataggaaaca tagatggtat agattttttt gaaagtataa
    45601 aagaaccaat aggttgtttt ggaaagtgta aggaaatgtc tcagggaaaa gatactacta
    45661 caggtcattg ggaaatgact ggtataatag ttgacaaacc atttaagaca tttgaacatg
    45721 gattctctaa ggagataata gaagagtttg agaaaaaaac tggaagaaaa gtagtaggaa
    45781 ataaaccagc ttcaggaact gtaataatag atgagtatgg agaacatcaa ataaaaactg
    45841 gagatgtaat agtatataca tcagctgata gtgtatttca gattgctgct aatgaagaag
    45901 taattcccct agaagaactc tataatatgt gcaaaatcgc tagggaaata atgatggggg
    45961 ataatgcagt agctagagta attgctagac cattcatagg taagaaaaaa ggtgagtttg
    46021 tgaggacttc aaatagaaga gattattcac tagacccatt tgaaccaaca gttcttgata
    46081 atataaaaga atcaggactt gatgttttag cagttggaaa aatagaagat atttttaata
    46141 gaaaaggaat tacagatgct atccacacta aaagcaatat ggatggagtg gatgaaactt
    46201 taaattatat gaaacaagat aataaaggtc taatatattc aaatctcgtt gattttgatt
    46261 ctaaatatgg tcataggaga gacccagaag gatataagaa agctcttgaa gagtttgata
    46321 gtagacttcc tgaaataatg gctaatatga gagaagatga tattttaata atcaatgcag
    46381 accatggaaa tgacccaaca tataaaggta cagaccatac aagagaatat atacctgtta
    46441 tgatttatgg caataagatt aaaaaaggtt ttaatttagg agtaaaagat acttttgctg
    46501 atattggagc aactgttgca gatatactaa atgtaaagtt gcctaaacat gggtcaagct
    46561 ttaaagaaga tttattttaa actataaaat gataaaaact tagcttaata ggatggagag
    46621 attggaatgt ttgaaaagat agcacaaagt agtaaattta taaattctaa aagtaatata
    46681 aaacctaaga ttggtttgat attaggttct ggactaggtg atttagcaaa tgatatagaa
    46741 gaccctgtca caattaaata tagtgaaatt ccaaacttcc ctgtatcaac agtagcagga
    46801 catgctggac aacttgtaat tggaaaactt gaaggaaaag aagttattgc tatgcaaggt
    46861 agatttcatt actatgaagg atattctcag aaagaagcta cttttccagt aagggttatg
    46921 aaagaattag gagtcgagat tcttatagta actaacgctg ctggaggcgt aaataaagaa
    46981 tttaaagcag gagatttgat gcttataaga gaccatataa actttagtgg aagtaatcca
    47041 ttagtaggaa aaaatgatga cagatttggt gctagatttc cagatatgtc agatgcatat
    47101 tcttctaaat atgtagatgt agttaaaaac tgcgctaaag aatgtaatat agatgtcaaa
    47161 gaaggcgttt atatgttttt tagtggtcca aactatgaaa caccagcaga agtgagaatg
    47221 gcacaaattt tgggagctga tgctgtaggt atgtctactg ttccagaagt catagtagct
    47281 tctcactcta atataggcgt tattggtata tcttgtataa caaatatggc tgctggcatc
    47341 ttaaatcaac cactaagtca tgaggaagta atagaaacta ctcaaaaagt taaatcagaa
    47401 tttatgaatt tagttaaaac aacggttaaa aatttataag ttaaagctta ttatagattt
    47461 tttgaggaag tttatcttaa aatagttaat gtttaatttg aaaagaatta ataaaaagct
    47521 gtcttgatat agaaagttat ttctaataaa ggacagtttt tttataatac tacaacattt
    47581 gaaagtgttt taaagtttaa tatttattta aattattata ggttagaatg gagatttcaa
    47641 ttatgagaat gtatgatatt ataaaaaaaa agagagataa cctagagctt agtaaaaaag
    47701 agataaacta ctttatagaa aactattcaa agggagatat acctgactat caagcttctg
    47761 cactattaat gtcgatttat ttaaataaga tgaataaaca ggaaactgta catcttacag
    47821 aagcaatgat gaactctgga gacatgataa acctatctga gatagatgga ataaaggtag
    47881 ataagcatag tactggtggt gttggagata aaactaccat agctcttata cctttggttg
    47941 cttcatgtgg agcaccagtt gcaaagatgt caggtagagg tcttggtcat actggtggta
    48001 ctattgataa attggagtct ataccaggtt tttcgacaga aatggagata agtaaattta
    48061 ttgattctgt aaataagtct aaaatagcag tttgtggtca aagtgcaaag gtagcaattg
    48121 cagataagaa aatatatgct cttagagatg ttacagcaac tgttgataat atatcattga
    48181 tatcatcaag tgtaatgtct aagaagttag cttcaggagc tgatgcaatt gtgctagatg
    48241 taaaaactgg tgatggagca tttatgaaga cattagaaga gtcttttgag ttagctaaat
    48301 ctatggttga tataggtact ggtatgaata gagatacaat agggattgta acagatatgg
    48361 atgaaccttt aggttttgca gtgggaaact ctttagaagt tatagaggca attgagacat
    48421 taaaaggaaa tggacctaaa gaccttgttg agctatgcga agtattagga gcatatatgt
    48481 tggttttatc aaaggtagca catgattttg aagatggtgt tgaaaaaata agagaatcaa
    48541 taaaatctgg tactgctata caaaaactca aagagtttat agagaatcaa ggtggtaata
    48601 aagatgtagt agatgattat tctttattca aaaaatcaaa gtataaatat ccagttaaat
    48661 caactaaatc aggttatata agcaaaatta aagctgaaga tgttggtgta tcggctatga
    48721 ttcttggagc aggtagagaa actaaagatg atattttaga tttatcagca gggataattt
    48781 tagaaaagaa agtaggagat tatgtaaatg aaggtgaagt tttagcttac atgtattata
    48841 atgatgaaca aaagctttca ttggcaaagg gaagatttat tgattcctac tctattgtag
    48901 attcaaaaat agaaaaaaat aaattaatat atggtattgt aactaaagaa gagattaaaa
    48961 agttttagaa aattttagaa aagtgattat aaaaggccta acatgtcaaa aataatgtta
    49021 ggttttttat tttttgataa actataaatt ataccaaaaa tatatatttt aaaacatttt
    49081 ttacaatata aataagttta ttctacaaga tgattgaaaa ttaaagtatc tagttttata
    49141 atagaaaatg gataaatata cataaggagt agattatatt atgaacttta aagaaaatag
    49201 attgaaaata gcagtattaa taattgttat tttgattatc ttagcaggta tatttgtgtt
    49261 tatacaaata ggtccttatg ataaaaataa caaaaaagat gtaattatcg acgttccaag
    49321 tggagcatct gttggaaaaa tatctgacat attatatgaa aataaattaa taaagaatga
    49381 actattattt aaacttttgg taaaggttag caataaagct ccgtctataa aatcaggaac
    49441 atacttactt aatcaatcgt attcaaacaa tgatataata agtcttttag tttcaggtaa
    49501 aatatatcag gatggtataa aagtgactat tccagaggga gctacatcta aagaaattat
    49561 agcaatgtta gtaagtaaaa atttaggaga taaagctact tttgaaaatt taataaaaaa
    49621 acctcaagaa ttttatgata aatttccata tttgaaggaa gatggaataa cctctttaga
    49681 agggttcttg tatccagaaa cttattattt taattcaaag aaacaatcag aagaagatat
    49741 tttaagcgaa atgttaaaag tatttgacag taaatacacg gacaagttta aaaagaaaca
    49801 aaaagaatta aatatgactc ttcaagaagt aatggaaatg gcatcaataa ttgagaaaga
    49861 agctgttctt gacaaagaca gacctataat agcaagtgtg ttttataata gacttaaggt
    49921 aggtatgcct cttcaatcag atgctacaat acaatatata tttgaagaga gaaagaaaat
    49981 tgtaacatat gatgatttaa aaattgattc accatataat agttataaaa ataagggatt
    50041 acctcctaca ccaatatcaa atcctggtat aaaatctatt gaagcagcat tatatccaga
    50101 gaaaacagac tatttatatt ttgtagctaa gattgatggt ggaaataatt atagtacaaa
    50161 ctatcaagac catttaaaat acgttaaaga atataaagaa gcaagggata aacaatcaaa
    50221 agatacaaaa gcaacaaata aagaaaatac aaaaaaataa accatgatta taaaaagtct
    50281 aacagggtaa gaataatgtt gggctttttt attgaaaatt gttattctta gatttataat
    50341 aaagaaagtg taaatatata taacaatatg aatttaaaaa ataataaatt aatataaaac
    50401 ttgaatattt attattttag ggagtgtttt tatgagtaat atagttaatg atttggttga
    50461 agattatata agagtgacat taaaagaaaa agaaggattt ttaaaagatt tagaaattta
    50521 tgcagaggaa aatagtgttc ctataataca taaagaagtt tcagatttat taaaagtctt
    50581 gttaaaggtt caaaaaccaa agagaatttt agaagtagga tgtgcaattg gttattcttc
    50641 tatttttttt gcaactatta taggaaaaga tgcagatata ataactgttg agagaaatga
    50701 aaaaatgata gaaaaagcaa aagaaaacat aaaattagct ggatttgaca ataacataac
    50761 tatactagaa ggagatgcag aagaaaaact tagtcaagtc caaggtgaat ttgaccttat
    50821 atttatagat gcagccaaag gtcaatataa gctatttttt gatttagtta tagataaatt
    50881 aaaagatggg ggacttttag tatctgataa tattttgtat aaaggtatgg ttgctcatga
    50941 tgattttgtt gtaagaagaa aaaagactat agttaaaaga atgagaaatt atttagatta
    51001 tatatgtaat tgtgactatt taagcacatc attggtacca ataggtgatg gtgtagcact
    51061 aagttataaa gaaagtaaaa gaggtgatgt agatggaatt aaataaagta gaacttttag
    51121 ctccagcagg tgatttggag agattgaaaa tagctataac atatggagca gatgccgttt
    51181 atataggtgg agaaattttt ggaatgaggt ctgcagcgaa gaattttagt aaggaagata
    51241 tggcagaggg agtagctttt gcacatgaaa gaggcaagaa agtattcgta acagtaaata
    51301 taatacctca taatgaagat tttctacaat tagaagacta tttgttggaa ctagaagaga
    51361 taggaataga tgcagttata atagctgacc caggagtgct tagtgtaatt aaaaaagtaa
    51421 ttccgaatat ggaaatacat ttaagtacac aagcaaatac aaccaattat ctaagtgcaa
    51481 acttctggta cgagcatgga ataaaaagag ttgtagtggc aagagaatta tcttttgatg
    51541 aaatatctga gataagagca aaaacacctt tagatatgga tatagaagcg tttatgcatg
    51601 gtgctatgtg tatttcttat tctggcagat gtttaataag caactatatg actggaagag
    51661 atgcaaacaa aggttcttgt gctcaatctt gtagatggca atatcatttg gtggaagaaa
    51721 aaagacctgg tgagtatttt ccaatatacg aagatgaaag gggtacattc ttctttaact
    51781 caaaagattt atgtatgata gagtatatac cagagttaat caaatctggt ataacaagtt
    51841 taaaaataga aggtagaatg aagactgcat actatgtagc tactgttgta agagcataca
    51901 gaatggcaat agatgaattt tacagagacc cagaaaactg gaagttcaat ccaatgtgga
    51961 tggaagaact aaaaaaaggt agtcatagac attttacatc aggtttttac ttgaataaac
    52021 caacaacaga agaccaaaat tatcaatcag catcatatgt tagaaactat gattttatag
    52081 gtatagttag agaaacagaa gatgaagatg gtcttattgt tgttgagcaa agaaataaaa
    52141 tgtgtgttgg tgatgaaata gaagttatgg gaccatataa agaaactatg tttactaaaa
    52201 ttgaagaaat gtacaatgaa gaaggagaag ctatagaatc agctcctcat cctagacaaa
    52261 tagtgaagtt aaagctatca gtaaaagttg gtaaagatta tatgcttaga aaagttatag
    52321 aagaaaaggt tgaagaataa taaaaaattg ataaaaatag tattagcccc ttagaaattg
    52381 tcaataatga aattatctaa ggggtgattt catgtcaaaa aagaagactc catttttgaa
    52441 aaaagtggga aagagaagct ggtgtatatt tactataatt ttaataattt atagtgtttt
    52501 aatttatagg ctagttgata tacaagtatt aaaaggtgat gaatacaaac aaagtgttga
    52561 atcacaaagc gttgagaaag tcgagttaaa tagtggaaga ggaataatct atgatagaaa
    52621 caacaagaag cttacagata caagtaaatc tcaggtatta attgttgaaa aagaaaaatt
    52681 aaataataac tataaaattt tggagcttat taagaaagct actaagatga atgatttaga
    52741 tatatataaa gctgtacaag agcaattgac acgccctata atacagattc agactaaaaa
    52801 tatcgatatc gataagagta tgaaaaaaga acttgagaaa aatggaataa tggtagaaga
    52861 aaaaactatg aggtacgcaa aagatggttt attatcacat acaataggat atataaaaga
    52921 agatgataaa tcaggtcaat caggaattga aaagagtatg gatagtgtac ttagaaattc
    52981 aaatgaaaag tatataagtg cttttaaagc tggagatgca ggaaatgaaa aatctctaaa
    53041 catactaaag ggaagtgtaa aaactgttga taataaggat aaagatagac atctaaaaac
    53101 tactattgat tataacattc aaaaaaaatt agaacaaata ctaaataaag aagaaaatcc
    53161 tacagcagca ataatctcgg aagcatctac aggtgaaatt cttgcaatgt gctctagacc
    53221 taattttgac caaaatgaca tatcaaaaag tttaaaagga aaaaatggag aatttgaaaa
    53281 tagagttata aaagcgacat atccaccagg gtctgtattt aagatggtag ttttattttc
    53341 tgcacttgaa aatggtgtta tagatgagaa ctatacttac aactgtacag gtaagactaa
    53401 agttgggaat actaatgaaa tactgcgatg taataaaaga gatggtcatg gtttccaaaa
    53461 cttaagacaa gctttttcta attcatgcaa tcctgcattt ttagatatag ctatgaaact
    53521 tggaaaagaa aagatactca aatctgctga aaaattacat ttatttgaaa aggttgatat
    53581 tggtcttgat gaagaaaaaa ttagagaagc tccaaaaaac atatcaataa gaaatttagc
    53641 tataggtcaa gaaaatatag aatttacacc acttcaaata aatcaaatga ctcaaataat
    53701 agctaataat ggaacattca aaccactata cttatataaa agtcttgtgg acaataatat
    53761 gaatacaata aaaacttata agtcttcaaa aaaagaagaa cttatttctc cctatgtgtg
    53821 tacacaagtt aaagaatata tgaagtctgt atctaggatt ggtacagcta aagacctaaa
    53881 agatattgaa ggtggttgtg gagttaaaac tggtacagct caaagcagtt taaataaaaa
    53941 agctatagac cacggatgga taacaggatt ttatcctgaa gaaagaccta agtatgtaat
    54001 aactgtgtta gtagaaggaa ctcaaaaagg aaataaatct gcaacaccta tatttaagga
    54061 aatatgtgaa agtataaaat aaattatgta ctataaaatt taaggatata tcgtaacttt
    54121 gattttagat agaaaatttt gtctaatgat gtacgatata tccttttaaa atatagtatt
    54181 aactttcttg aacaagctct ttttctagtt ttttaagagc ttttttttcg attctagata
    54241 catatgacct tgatatatcg agtttttgtg caatttctct ttgtgtctta tagccataag
    54301 gagttaaccc atatcttaac tggacaattt ctctttctct aggagtaaga attttgttta
    54361 gttgttcgta aagttttcca acttgaactt ttagttcaac ttcatcaaga acatagttag
    54421 cctctgtacc aagtatatct aaaagactta tttcattaca cactactctt tatatgttat
    54481 tggtattact ggtcttcatg taatttcaaa tggaccatta attcaaaaga atctagtttt
    54541 tgttctttag acttataata aattgcttta tcaattacag attttaggag tttatttttt
    54601 ccaagggaat ctgaatcatg gtaaagtgat aacacagttt taatatcttc tattatttta
    54661 gaattgtctt ttttaacagt actcaatcta ttttttactg tcttaattga atctttaatt
    54721 tcttcagttc ttgaacttat attgttggac ctttcaataa atgtatcttc atcatatatt
    54781 cctcgttcta gtaaatcata taacttattt ttttgcttgc ctaattcttt taattcagtt
    54841 tctaaaccct ttaagactcg tttttgaaat tctatattac tatctttatt atttttatct
    54901 aagtctatat cagatgtttt taattgatat ttttttacag tgtcttccaa agattttaaa
    54961 atggcagctt caataaattc aaatcgagaa cttttattgc aaccaggatg ataacaaatt
    55021 atatagtcat ggtctgcata tggtctatat actaatggtc taccacaatt tttgcaaatc
    55081 actattcctg caagtggatt ttttatttga ttaccatagc tgacatgacc attttttttg
    55141 agtatatttt gagctttttt ccatgttatt tcacttatta aaggttcatg ctttcctttt
    55201 gcctcaatcc attcatcttt aggtcttagt ttaactgttt ttattttatt tggattttta
    55261 gattttttgt agtccttttt ttgccactga atgtagccac aatatacctt attttttatt
    55321 atatttgtaa ttgcagaatt gtaccaatta gcacctgtag cagttttaat gcctaagtta
    55381 tttaggtatt ttgatatttt actacaaccc atatcttcat taatatataa gtcaaagata
    55441 gtcctaacta catcagcatc tttatttggt acaagtattc tttcttttct accagttgtt
    55501 acagcatcat atccaaatgg agcagaggtt cctataaaat tcccttcttc aactgatttt
    55561 attctacctc tttgcatcct tcttgatata agttttaatt cttttcttgc cataaatgct
    55621 tcaaattctg aatactcctc atcaaattca tctgttaggt cgtatgtttt tctaggtgtg
    55681 ataattttgg tcttactttc tttgaatgtt tctaatatga taccttggtc tttcatgtct
    55741 ccacgaccaa gtctgtctaa gtccattact aagactgcat catatttatt ttcttcaact
    55801 tcttttagaa gttcaagcat tttaggtcta tgtattatac tttcaccaga aactaattct
    55861 tcttttatct caattacatc taagttttgt tctttggcta gttttagtag ggttgattta
    55921 tgtctactta aagtttcaaa ttcgccttgt ttttctgcct cttcatcagc acgggatttt
    55981 cttaagtata tggcaacact cataataagt aatcacactc cttatgcact attatatagt
    56041 aaatcaatag agtttaaaat atagaaaata agcatgtcaa aagttaattt aactttcaac
    56101 atacttattt tctataatat taatgcctta taatccttta atatcattta gattagtttt
    56161 tgcatattca ttatccgggt taagttcaag cgccttattg taagattctc tagctttatt
    56221 aaattctgat ttactcataa aaataacacc tcttaaattg taagcatcac tagcgtctat
    56281 tttataagct tcattatttt tatctagata ttctaagtat ttatcaattg actttaaagc
    56341 ctcatcatat cgttgtaact ctatataaat atatgattgt gtataatatg caagtggatt
    56401 tttatcatca atttctatag cttttttgat atcaatagca gctttattat aatccttatc
    56461 ttcatctttt tctgtttctg acctagcgat tttgacataa ttagagctaa gagctctttt
    56521 aaagtcttta tgccataata atttatattc attatcttcg attataaaat atctatcaaa
    56581 atttgcagta tcttctttat tttcagtgat atactttata gtatcagttt cttttatttt
    56641 aacaagattt gtgtactctt tattagaata tttgtatttc tctactttat tttcttcacc
    56701 aagtttataa tcttttaggg tttgaagttt aaataaagta tcttgatatt cttcaaattt
    56761 ttctagactg acactttcct tactgtcttt acttaataaa ttatatgcta cttcgtagtc
    56821 tttgatttct atactatcaa ggtacttttt agctacttct gtagcacttt cttttggagc
    56881 acatccaacc attgatatca taattaaaaa tgatactaat attgctgtta tttttttact
    56941 gattatcata atataatccc ccttatattg tctctcatta attttatttt atcaccatat
    57001 tctaccaaag tcattaattt aagagtgata tttttcatta atattatatt aagtaataat
    57061 aactttttaa gtttatggta acattttcct gaaaagtatt atataattta ggtgaaaata
    57121 tttaagagaa ggagatatta tgaaaattaa aaaattatta acaatagggt tatctttatc
    57181 tatatttatt gctagttgcc ctatatctgc aaatgctctt gataaaattg aatcaattaa
    57241 aggtgtagat aaatacgaaa ctgctggtat aattgcagac aaacaaaact atactacagc
    57301 tatattaatt aatgcagaca gtacaatggc tgatggatta agtgcaagtg gacttgcagg
    57361 agctataaac gctccaattc ttttgactaa gaaaaataac atacaaaatg ctacacttaa
    57421 aagattagaa aaggcaaaaa aagtatatat aattggagga gaaaactcta ttgataaata
    57481 tactgaaact gttctaaaag gcaaaggaat agagattaaa agacttcaag gtagtgatag
    57541 aattaagaca agctataatg tcgcaaaaga aataaactca attaacaaag taaataaagt
    57601 catattgact aatgctttta aaggagagcc tgatgcaatg agtgctgcac ctgtagcagt
    57661 tagagataaa gcagctatag tattaactga tggaaaaagt gttccattta atacaactgg
    57721 tgtagaaagc tatgtaatag gtggtacttc atcaatgaat gacaaactag ttaaggatac
    57781 taattcaact agattaggtg ggacagatag atatgatact aacaaaaaga taataaataa
    57841 attttatagt ggagtaaaag aattttatat agcaagtggt actgatttag tgtatgctct
    57901 tgttggttct accattgcta aaaataatgc tattgtgtta gttgataatg atagtaataa
    57961 aagtgtattg aaaagtacaa ctaaattaac tgctatagga aatttgagtg atagtatatt
    58021 acagcagtgt ttaaatgtaa caaaaaatat aggcgattct aatactggaa gagaatatac
    58081 agtagaagat gctgctaatg cagtgaaaaa actattaggt gtgaagaaat tttattacga
    58141 acctaattat tcagaagatg aagatttaat atttctacta gataaaaatt ttgatttttc
    58201 aggaaaagag tactatgtat ttgcttacat taaacagggt gcagagggtg atgttagata
    58261 ctgtgtagct aaaaatgata tgagcaaagt ttatacatat gatgttaatg gtaatatgaa
    58321 agtatgtaat ccagatgatt ataaaaataa aggaagtata acagaggaac aagcaaaaca
    58381 gatagcatta aaagaatgtg ctaagagaca taaagtcagt atcaataact tagtagttga
    58441 tatgatagat tttagagatg atatatatag tggtaatgtc tatgctgtta aaatcaattc
    58501 aaaaaatagt aatggtactt ttggttggtt ttttatagat atagaaactg ggaaagttta
    58561 taattaaaat tagaactttt aaacaagtgt ttttaattat ataatttacc ataatatgtt
    58621 ataatatttt tagcaagaag atttaactta caatctatag agtggagttc atgtacaaaa
    58681 gattatcctc ccaacgattc gaagggaggt gagttcatgg ataacttttt gtttaatgtt
    58741 ttagctagtt taacagctag tgtggtagtt tacttaatca gtaaactatt caaaaaagca
    58801 aaaagccact ctcgcacaaa gagtgactta cgagttgaat ttaaatttat atttaaatcc
    58861 aaaaaataaa ctctgtttat gatgaactcc actctaacgc aaaatagatt gtagttcttc
    58921 ttgcttttat tataccacaa aacattataa ataaaactgt tgtttataaa aaaatgcaaa
    58981 gtaaaatttt ttataaacaa tgataaaaat tttattatag agctattaac ttatgaaata
    59041 tctgtaaatg agcagatatt tcataagtta atatttattg tttacataaa atatttggta
    59101 aaaataagta agttttatat gttataatag ttgtagcaag aataataatc taaagtggca
    59161 agcatgtcag ctggtgttat atcagtttat atttatgata aaataaaaat ctcccaaacg
    59221 ccaataagaa tgatttaaaa aaataatatt ttcacttaaa aataatcact ctttatagga
    59281 gtaaattatt ttcttgattt tattatacta caaattggta cagatattta aaaataatat
    59341 attcataata ttataaatag ttttgcagtg agcgatattt ttgataaaat agggcttaac
    59401 agttgaaaca taaggcattt agggtatatg ataaatatta tcatttgcac tactcgtggt
    59461 tcactgcaaa tttgagagaa ttgtatagat gtaagtgttg gaaatactca atttattttg
    59521 gggttttata ttaactaagt ggtatgtaaa gaatttactt cgcatataac acgctcaatc
    59581 agttcaaggt tttatattaa ctaagtggta tgtaaagtaa cttcattttg taaatgtctt
    59641 gcaatacagt gtaaagtttt atattaacta agtggtatgt aaagaaatta tatagctctt
    59701 tatttaattt tgcattcata gttttatatt aactaagtgg tatgtaaagc attcccttaa
    59761 gtaaccatct atttctttgc tgactagttt tatattaact aagtggtatg taaagacaga
    59821 tataatatca aaataaggtt aggactttta aaagcatagc catatcagta aaaatttaat
    59881 tatcatttaa aaaataaatt tttatttaaa gaatacacat aaatatttcc agactcaact
    59941 ctcttaaact attttcatat cttttagtag atacctttgt tgttttttaa cctttagcaa
    60001 cttgttcttg agtgaacctc ttattttttc taagttattt caagcttttc aaaaaattct
    60061 ctatttatat tcatcacaca tataatacaa ttaattcagt tttaattgcc aatatttagt
    60121 ttttctgtat ctgataagcc aagaatataa tcagtatata aaccaaaaat tttagcaaat
    60181 attattaacc catcgtctct tattggtctc tcaccagact ctattctatt cataacactt
    60241 gtatttatat ttgttttttc aagcaattct ttttgagaac tattcatatt ttccctagta
    60301 tatttaatcc tttgatttac atccatacat aattatctcg aaaagtttct gctttggaaa
    60361 tattgttatt gaaatataga aattaatgtg aatatatgaa aaagatacac tatgatttta
    60421 taaaaaagaa gacatacata aaatttatac ttacaaagtg ttgcaaaaga gttaggtttt
    60481 aaaaatgcat caacttattt taagtacagg aaagggtaat attcaattag agttgatata
    60541 ttacctataa actatctaag atacttgatt atgatataga aaatttaatt aagaggatga
    60601 taaggatgaa taatttacaa gtaatataaa gaaataataa gagaatttta aatacatagc
    60661 aactagcaga tatatatgaa aatgatgtaa acaatatata aactaacttc aatagaaata
    60721 aagagaatgt aaattatgtt ttattacaat tcgagtattt gaaagaattt aagaactaac
    60781 ctactaatag tcagttgatt tcaaaacatt ctagtcaatt atacctttgg acccaaagat
    60841 gtgcaaatag acactgcaaa atattagata ttgataaaac ttgggaacaa tttgacaatt
    60901 tagagaaaag atatttcaag attaagcgag agaaactaac ctgtatagaa gatgtattaa
    60961 tagaaaattt aaggatacaa attaatcaag caataatatg acattagagg taaaaataga
    61021 agttaaaata ataaaagatg ttgttatatt aaatataaca cattggaaaa aagaaacaag
    61081 tctattaaca gttaaaatag ctagaagtca aggtgattta agttatgtaa aatattttgc
    61141 taatgagagc taagagcttc ttaacaagag ttttggtgtg tctcttgaaa caaggttaac
    61201 aattaataaa agacgaatgg gagaagaagg cgtatgtaag tttaaaagag ataagttaaa
    61261 caaactagat actatataag aggataagaa acttatagaa gaatatgtta cttttgtaaa
    61321 ggatttagct ttaaaatata gaatataaag tgattttaag taaaaattgt aacaattaaa
    61381 taagtataag acaagtttat gagttcatat tttataacaa ggggtgatgt tatgaaaata
    61441 ctacaacaat ttaaaccata caaatatgat aaagaaaaaa atatagaata tgatgaaaaa
    61501 attatagcta atcaaaacac agaagtttat atagtatatc cacgtatatc tgatgaagaa
    61561 aataggagaa gatgggaaga gttcaatgaa gtagctaaag aagtagctat taatatagct
    61621 atgaagaaag ttgagacagt agaaagttaa gagaatagag aagttgctaa tacttagcac
    61681 tttctcatag aagaaaattg gacaactatt tttaaataat taggagtaaa aaagttaaat
    61741 catatttgaa aaaaggcgat aaaattgttg agtattgtta ttagtaataa gaatgtatta
    61801 aaagaaatta taagttttta gtaaatatag tatttaagaa tattaaaact ggtaaaaaat
    61861 atcatttaga ctattaaata aaaaagtgct ggtcaaagta agcaacacaa taaataaaaa
    61921 aacttataga aattataaga taaaaagatg agatttgaaa tggttgaagt taatataaaa
    61981 attaaaggtg aagtaagtga aataattgac tcaattagag gtatatttaa tagctttgat
    62041 gaagagttaa tattagatat aaaatcagag taagaatata aaggtagata cgtagaaagt
    62101 tataagtaat tcaagactta aattaatttc tagttttttt aatgcaaaaa tttaataaat
    62161 ttcaaagtat aataattctg acatctaaaa agagctatta aaaatgaata atattgacta
    62221 ttaagatatg aatagtgtac atatattaaa ttaagatatc cagtaggtta attttatata
    62281 atgatggggc tcaaattgaa gaggcgatat aaaaatgtat taatatatat aaatataaga
    62341 actataatac atattaactg taaaattaaa tttatagagt tatatttaac atttaatgaa
    62401 ctgaaaaata aattagcaaa taatgaaaaa acaacagtaa taaatgagaa taacaaagca
    62461 ttctcaggat tagtggattt ttctaattga gctttaatcc tagtttgttc aatttcgata
    62521 tttctaatat tattaatatt atcaatttat ttgtaataat tatcaatttt tgcgaaatat
    62581 ttttgataat ttatagaact ttatatattt tccttaaagt attttttgcc cttattgttt
    62641 ggtttccaat tttaaaactc ataaactccc aataaattca tgtataatat accttaattt
    62701 ataatatatt taagagttta tttcagtaat ttttcgaacg attttgatat atttcattta
    62761 tagtttttaa aaacttatac aaaaaagagt gtttcatttt tctaaacact ctttttataa
    62821 gaatttgaat aataattttt taaaaattga taatatggtt atttcttttt caagtttata
    62881 gtttcctcat ttccattcca agatataatt agcttgtaac tagattctct atttgaataa
    62941 agacctggtc tttgtatttt tattgctttt tcttgacctg cttctaaaat ttcatttttt
    63001 acaactacaa ctgcatcttc accatctata aattgatagg aataattaaa tttttgttca
    63061 actacatctt tactattttt atattttatt tctaattttg agtgtccttc agtagttaca
    63121 aatttagctt tccaattttc tgattctcca ataaagacat ttttatcatt ttttatatta
    63181 agtatagcta tcacagagat tattaaaact ataagaatac ctataaaaaa ttttttcctc
    63241 atatcaatcc ctcctttgaa taattataac atgagaatag ttattcaata ctaattttaa
    63301 aaatattgtg aatttatatt ctattacaat agaatatctg ttataacaaa taaaaagtag
    63361 ggattaatat gaattatagg ttaaaaaaat ctgtaacaac tattttatct ttactcataa
    63421 tgacaatact attaccaaca aatgcaagtg ctagtaaggt agaagattca tctatgaaag
    63481 taatgtattc agagaaacaa gtaacagaca tggacaaatt atacgatatg gctaaaaatg
    63541 gaattactga tgttaaaagt tccaatgaaa aaggtataat caaaaatgca agaacaggag
    63601 agtccatata cgttgattct atatcaacaa ctcaattatt agaagttaaa caatctaaaa
    63661 atttaacatc aaagatatat tctaagacag ttttttgata ctaatacaat aaagcctctt
    63721 agaaaagcaa gtatatcaga agatggatgg gataaaactg gtggtgtaaa agcatctggt
    63781 acagttacat atacaatatc aaaaggagat ggagcatttc aatatatttc cgttagtaaa
    63841 gtttctggaa actggtctat tgcagacggc cagattcgtg taacaaatag aagggtgcat
    63901 ataaatcaaa ctggatttat ttctaatggg ctggaattaa gcagcaacaa aagaaagagc
    63961 caacatcaaa ttctttctca tataatgcac cttctagttg gaaaccagta ggtagagatt
    64021 cagttcaata caattgtggg tttgaattaa ttacaacatt agtaagagaa ggaagttctt
    64081 gggcattcaa tttcattgtt caactttaaa atattttaag tgaattttat taaaattaaa
    64141 gatatacata tactttaaaa ttagagaatg taaattaatt tgtgttttta aagataattc
    64201 ctatgttata gtaacaattg cttatttact attaatattt cttaatatat gaattt
//
LOCUS       DAEQAF010000009        60637 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.009, whole genome shotgun sequence.
ACCESSION   DAEQAF010000009 DAEQAF010000000
VERSION     DAEQAF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 60637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60637
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.009"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            147..797
                     /locus_tag="KRN00_000725"
     CDS             147..797
                     /locus_tag="KRN00_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBH1826610.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(937..2313)
                     /locus_tag="KRN00_000726"
     CDS             complement(937..2313)
                     /locus_tag="KRN00_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1826611.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2329..4242)
                     /locus_tag="KRN00_000727"
     CDS             complement(2329..4242)
                     /locus_tag="KRN00_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1826612.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4378..5010
                     /locus_tag="KRN00_000728"
     CDS             4378..5010
                     /locus_tag="KRN00_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBH1826613.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5149..5688
                     /locus_tag="KRN00_000729"
     CDS             5149..5688
                     /locus_tag="KRN00_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH1826614.1"
                     /translation="MVFVEELWKKAIEFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(5864..6034)
                     /locus_tag="KRN00_000730"
     CDS             complement(5864..6034)
                     /locus_tag="KRN00_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1826615.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6319..7386
                     /locus_tag="KRN00_000731"
     CDS             6319..7386
                     /locus_tag="KRN00_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBH1826616.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDIIISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     NVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            7556..9457
                     /gene="cooS"
                     /locus_tag="KRN00_000732"
     CDS             7556..9457
                     /gene="cooS"
                     /locus_tag="KRN00_000732"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH1826617.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENIAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIINRRKNL
                     GLKDVECNA"
     gene            9450..9923
                     /locus_tag="KRN00_000733"
     CDS             9450..9923
                     /locus_tag="KRN00_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1826618.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            9898..11124
                     /locus_tag="KRN00_000734"
     CDS             9898..11124
                     /locus_tag="KRN00_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1826619.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSI"
     gene            complement(11263..12450)
                     /locus_tag="KRN00_000735"
     CDS             complement(11263..12450)
                     /locus_tag="KRN00_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1826620.1"
                     /translation="MNITKNFLKDYLEKFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNARIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            12723..13547
                     /locus_tag="KRN00_000736"
     CDS             12723..13547
                     /locus_tag="KRN00_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1826621.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVYKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNRNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            13676..14941
                     /gene="gluD"
                     /locus_tag="KRN00_000737"
     CDS             13676..14941
                     /gene="gluD"
                     /locus_tag="KRN00_000737"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBH1826622.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            15154..15744
                     /locus_tag="KRN00_000738"
     CDS             15154..15744
                     /locus_tag="KRN00_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH1826623.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDK
                     RVLKNCTVQQKQEYVLTIVNSMKRSTNFSNKFVAGLNNQSDIRKRVMNMFSEKHKNGI
                     LMALIISLFSSITFFKFDSTSIIEENDFLERLRYTFEGRQEDMFVTIDFTYADAPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            16074..17207
                     /locus_tag="KRN00_000739"
     CDS             16074..17207
                     /locus_tag="KRN00_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBH1826624.1"
                     /translation="MSNFILNGIFRTVIVSSLSILMILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNVLPKGMEEKDVTNSAIVTMIEF
                     TYAEAPKSMRERYKINCEFLGLIPKDSDKIGVGVEYYDSLLND"
     gene            18123..19145
                     /locus_tag="KRN00_000740"
     CDS             18123..19145
                     /locus_tag="KRN00_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1826625.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSIDQNVDSTNNNQQNNANTNQQNNNSNVPTANSNA
                     VQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSKAQSKYGQTV
                     SKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSINSSYYTARFV
                     TAKRIL"
     gene            19440..20360
                     /gene="pyrB"
                     /locus_tag="KRN00_000741"
     CDS             19440..20360
                     /gene="pyrB"
                     /locus_tag="KRN00_000741"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBH1826626.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKVTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            20399..21091
                     /locus_tag="KRN00_000742"
     CDS             20399..21091
                     /locus_tag="KRN00_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBH1826627.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDNIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            21084..21986
                     /locus_tag="KRN00_000743"
     CDS             21084..21986
                     /locus_tag="KRN00_000743"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH1826628.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKNRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            22071..22655
                     /locus_tag="KRN00_000744"
     CDS             22071..22655
                     /locus_tag="KRN00_000744"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBH1826629.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            22870..23796
                     /locus_tag="KRN00_000745"
     CDS             22870..23796
                     /locus_tag="KRN00_000745"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBH1826630.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITEVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(23848..24738)
                     /locus_tag="KRN00_000746"
     CDS             complement(23848..24738)
                     /locus_tag="KRN00_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1826631.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            24926..25957
                     /locus_tag="KRN00_000747"
     CDS             24926..25957
                     /locus_tag="KRN00_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBH1826632.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNVIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            26251..27126
                     /locus_tag="KRN00_000748"
     CDS             26251..27126
                     /locus_tag="KRN00_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HBH1826633.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYTEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRIYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            27144..28634
                     /gene="cls"
                     /locus_tag="KRN00_000749"
     CDS             27144..28634
                     /gene="cls"
                     /locus_tag="KRN00_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH1826634.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            28827..29111
                     /locus_tag="KRN00_000750"
     CDS             28827..29111
                     /locus_tag="KRN00_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBH1826635.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            29144..30772
                     /gene="groL"
                     /locus_tag="KRN00_000751"
     CDS             29144..30772
                     /gene="groL"
                     /locus_tag="KRN00_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBH1826636.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            31034..31774
                     /gene="larB"
                     /locus_tag="KRN00_000752"
     CDS             31034..31774
                     /gene="larB"
                     /locus_tag="KRN00_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBH1826637.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            31858..32592
                     /gene="larC"
                     /locus_tag="KRN00_000753"
     CDS             31858..32592
                     /gene="larC"
                     /locus_tag="KRN00_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBH1826638.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            32622..33041
                     /locus_tag="KRN00_000754"
     CDS             32622..33041
                     /locus_tag="KRN00_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBH1826639.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKLSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILERKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      33101..33202
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            33423..34958
                     /gene="guaA"
                     /locus_tag="KRN00_000755"
     CDS             33423..34958
                     /gene="guaA"
                     /locus_tag="KRN00_000755"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBH1826640.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            35204..35407
                     /locus_tag="KRN00_000756"
     CDS             35204..35407
                     /locus_tag="KRN00_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004801982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1826641.1"
                     /translation="MLLSYSGTKIFLNLKEAANLLNISQQQIYKIIRDMNKKLAEYAF
                     LVIRVEINKKYFFEQIYKAKKIQ"
     gene            35407..36162
                     /locus_tag="KRN00_000757"
                     /pseudo
     CDS             35407..36162
                     /locus_tag="KRN00_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003071689.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            36197..36586
                     /locus_tag="KRN00_000758"
                     /pseudo
     CDS             36197..36586
                     /locus_tag="KRN00_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005538919.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36809..37030
                     /locus_tag="KRN00_000759"
     CDS             36809..37030
                     /locus_tag="KRN00_000759"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826642.1"
                     /translation="MRPVTKSSNNWNKKESWINFETPVNNFGSSGFDRLYFVSTREDS
                     FICVRLDKIDITHYDCILKGFEDIYKEIS"
     gene            37540..37743
                     /locus_tag="KRN00_000760"
     CDS             37540..37743
                     /locus_tag="KRN00_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009644028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826643.1"
                     /translation="MKVSYKKLWHMLLDKNMKKKELAKLAGISTYTINKLNKNENVTV
                     EIIGKICLVLDCKVDEILEFSKE"
     gene            37864..39624
                     /locus_tag="KRN00_000761"
     CDS             37864..39624
                     /locus_tag="KRN00_000761"
                     /inference="COORDINATES: protein
                     motif:HMM:NF013704.1,HMM:NF036754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBH1826644.1"
                     /translation="MLNQFKEMLKEEDIEFNKEGYELKFLGKTYARYLSSTKTETFIA
                     PHNKHNEKDENKSSDNLYIIGDNLDALKHLLGSYAGKIKCIYIDPPYNTGSDGFVYPD
                     NFKFNAKELSTAIGIEEEEAQRIINLAGKSSHSAWLTFMYPRLILARELLSNDGVIFI
                     SIDDNEQANLKLMCDEVFGEENIIANFIWNNKYTVSNDTDISYQHETITCYSKSRNIF
                     ELNLLPRTEKQNKDYKNRDNDPKGPWKSTPLHARSGTESGLYEVTFDNGITWKAPIGR
                     FPRYSKDKLLELYNNGELYFNKNGGVDKKTYLSEVRKGITCGSLWSYDDVGHSHGNNE
                     ELANLIGKGIFNDPKGTLLLNRILMIATLKNSIVLDFFSGSATTAHAVMQLNAEDGGN
                     RKYIMVQLPEIIKEDKPAYKAGYRTIDEIGRERIARAAKKIKEETNADIDYGFKLYSL
                     ENVTVDTLVTLDYFNNDPKLELDNLVSVFDTVHSKGKDAILSTWLAQDGYGLTVHTKK
                     YKLKTYEADKIGDSLYLISKEIKSEDIMELIKRIEKMELDITRVVVYASSMHFSELHE
                     LKKNLNNLKNNKNVELIERY"
     gene            39626..42577
                     /locus_tag="KRN00_000762"
     CDS             39626..42577
                     /locus_tag="KRN00_000762"
                     /inference="COORDINATES: protein motif:HMM:NF012027.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction-modification system
                     endonuclease"
                     /protein_id="HBH1826645.1"
                     /translation="MGIKLSILPHQMECLERVVKVFEDVRIEAREEIFANPIIDITSE
                     TLRNNIQDMQSNFGDNSIPKELRTRRDDFGIDVRMETGTGKTYCYTRLMYELNKKFGF
                     HKFILLVPTTPIKEGTKSFIESNYANKHFSDLYPGKRITLSVLNPQKRVKGKKKMFPQ
                     AISDYARGTRLESGRINVLLMSSGMLLSKATMDDDYDQTLFGSFSNPYETLKATRPII
                     IIDEPHKFKIENKAYTTLIERINPQCVIRFGATFPNKPKSIDKDYNNLVFNLGACEAF
                     NQNLVKGVITQMIHQENLNETKVKLMDFKIKGKTCVFRNEKTLKSFTLTIGDSLSIVD
                     SDFYGITIERIGKTDNEEIKTGVILSNGQILAKGDQIYAGVYAHTYQELMMKQAIKNH
                     MEQEKINFFKERKIKTLSLFFIDSIYAYRGEEGDGSLRISFQKLLKEALEKELEYYKE
                     TKVEIEKDYVSFLESSLKDISKTNGGYFAEDNSVADEDIQKEVDQILRDKESLLSFKD
                     EEGNWNTRRFIFSKWTLREGWDNPNVFQICKLRSSGSEISKLQEVGRGLRLPVDEYGN
                     RVSDEQFYLTYLYDCSEKYFANNLIKEVNSDSKVNLTSIKTMLEKVARDRGVEEKQLF
                     AALLINDFIDVDGNINLEKYSEFILNYPEFNTGLEQNKIVDKNKKDIGTVRIRKDKFS
                     EINDLWNKINQKYYLKLDDIEEQELYNAALNILKTDIAVQTMARTIQQKTDIEDGKLI
                     LKEEIEGYYVLDDSIPYNKFLQQIQKATGLSMSIMHKALCEYNKTKLLDKSFFNHNTL
                     TKFIEKFQHWFEQAFLKRFSYKSLDVNSLETSLTDINGEPKEKIVQGVVGIIKDDNLS
                     VPDNFLYDAVVFDSEKEKENIKNSNIDEVVVFGKIPRRSVQVPLYFGGTTSPDFMYVI
                     KKDEEHELNFIVETKDVKKESSLRRDEDLRIASAKKFFGELKKEGINVSFEKQLQSDD
                     IVGMIRNLLTK"
     gene            42672..42818
                     /locus_tag="KRN00_000763"
     CDS             42672..42818
                     /locus_tag="KRN00_000763"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826646.1"
                     /translation="MYDGLDLDNFEIVNKYYAIDQGIVLEELDMGNISDMQGFNIVFE
                     YYII"
     gene            complement(43079..43650)
                     /locus_tag="KRN00_000764"
                     /pseudo
     CDS             complement(43079..43650)
                     /locus_tag="KRN00_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420927.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            43930..45360
                     /locus_tag="KRN00_000765"
     CDS             43930..45360
                     /locus_tag="KRN00_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1826647.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPRNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(45508..46383)
                     /locus_tag="KRN00_000766"
     CDS             complement(45508..46383)
                     /locus_tag="KRN00_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1826648.1"
                     /translation="MINIRYLEILEAIEQTGTFTGAAKKLHITQSAVSHAIAELEQQA
                     ETALFDRLPRGVCLTRCGISLLEEARSILTACRNLDKRISHLEECTPINIVSSITIAS
                     FLLPPILSRLKNSFPSLKVNVRVESANSAMDILKSGEADICFWEGIEPQGAFRTILLG
                     SYKLCVACAPTFPLSKQALSLRQLCTFPLLLREQGSAIRDTLDSVLSLSNQKAYPVWE
                     SVNSFALIKAAEAGLGITILPENLLLDSLFHKKLRLIKLDGIDMENKMLAILHKDKNI
                     TQPLKIILDNISNVL"
     gene            46503..47066
                     /locus_tag="KRN00_000767"
     CDS             46503..47066
                     /locus_tag="KRN00_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1826649.1"
                     /translation="MNQSRKTYFWLLIINLFISTFTFGGGYVVVPMIRRYFVNQKQFF
                     TEDDLMSMAAVAQSTPGAIAINLSALAGYRVAGTLGVVISCIAAIIPPLVILGLVSAF
                     YTTFISNAIVIAVLKGMQAGVAALIVDLIIDMCSMILKQRSLFLSAMIPIAFFANFVM
                     SINVIFILSVCCFVCVMQVFYKKRENK"
     gene            47063..47629
                     /locus_tag="KRN00_000768"
     CDS             47063..47629
                     /locus_tag="KRN00_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1826650.1"
                     /translation="MNTIWNLFFIFLKIGLFSIGGGYAIIPLIQEKVVNQTGWISEKI
                     FTDIITISQMTPGPLAVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKH
                     QNSTYIFEILNGLKSASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFV
                     TLLIVRKWKINPIVIIIISGILGIFFYL"
     gene            complement(47758..47994)
                     /locus_tag="KRN00_000769"
     CDS             complement(47758..47994)
                     /locus_tag="KRN00_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826651.1"
                     /translation="MLECFIAEDSKIKDGVNIPTLVFKTLHDRYFKTQYFDSYYNSLK
                     CKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(48304..51732)
                     /gene="uvrA"
                     /locus_tag="KRN00_000770"
     CDS             complement(48304..51732)
                     /gene="uvrA"
                     /locus_tag="KRN00_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1826652.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESEITYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCRQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKDLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLSNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTISIL
                     DGATYYFGKLRGKKPNGNWMVGELYAIAKDKNIDLDIPWNELPRDFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPSAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKTGSQNKTIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSIPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPATYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVAEAKTFFSDCSDIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            52051..54285
                     /locus_tag="KRN00_000771"
     CDS             52051..54285
                     /locus_tag="KRN00_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1826653.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGEGTIEIINSKGKPLFIGKNTELIKDLSHKYKDSADQP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITIGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNVLYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEDDTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            54541..56571
                     /locus_tag="KRN00_000772"
     CDS             54541..56571
                     /locus_tag="KRN00_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1826654.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKDWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            56568..57020
                     /locus_tag="KRN00_000773"
     CDS             56568..57020
                     /locus_tag="KRN00_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1826655.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            57022..58077
                     /locus_tag="KRN00_000774"
     CDS             57022..58077
                     /locus_tag="KRN00_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBH1826656.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLIGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     IGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            58144..58452
                     /locus_tag="KRN00_000775"
     CDS             58144..58452
                     /locus_tag="KRN00_000775"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBH1826657.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            58556..59821
                     /locus_tag="KRN00_000776"
     CDS             58556..59821
                     /locus_tag="KRN00_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBH1826658.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            59909..60625
                     /locus_tag="KRN00_000777"
     CDS             59909..60625
                     /locus_tag="KRN00_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1826659.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGYEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
BASE COUNT        23404 a         6869 c        10466 g        19898 t
ORIGIN      
        1 tatatatgta taagtttatt ctgcgtgagt agaatgaatt tgtcaagttt aatttagttg
       61 taattgtatc ttttattaaa aataatataa attaaaacat ataaataaaa tattttatac
      121 aatatattgt aaaggaggta actttgatga aagcagaaaa aacaagtata tatccaatta
      181 ttaaaaataa tttaaacaaa atatcaattg ttgaatataa aaagggtcaa agatttgtag
      241 catcagataa agacttacaa gaagtgttct ttataataga gggagttgca ttagtggagt
      301 gtactactag aggaggaaat aaatttcttg ttgacattgt acctgaaaat gaatttatag
      361 gcaaaattag ttacatatat gaacataatt tgaaatgtga tatatttgca aagaccaata
      421 taaaattatt tcgatttgaa aaaaatgtat ttgaagagtt ttatctcaaa ccagatttta
      481 ttgcactatt tcacagaaaa tgtacaagaa gaatatatga attatataaa accagaatgg
      541 taagagaact attttcttgc acagaagtta ttgcctattg tatatcaaat aaacaagaaa
      601 ataatgtctg caatataaaa gctattcgta atttcagtga aatctattca attagtagaa
      661 aaagtagata ccattctctg ctaaagttaa ctgaaaagga gatagtaaaa aaaatgggta
      721 atacatatga aattttaaac tatgatgaat tacataaatt ggcatttgaa gtaaaagaat
      781 ttttggaaga tgagtaaaaa ttgttactta atcaaaataa agtataataa tttctgtaaa
      841 aaatagaaat agtctcactg aaaatcaaaa atactttagt tattttcaat gagactgttt
      901 agaaatattg tatacttata atgtatagta taattattaa tcaatttcct ttactatatt
      961 aatagcccat tttttagata atgctctagg aacaccaaat ataaacttaa ccacttcttc
     1021 actataagtg agcaaaacga gtacaaatat aggtgcacct ttaaatgcag ctataaaagt
     1081 tagaggaata gaagctaacc acatacatcc taattctaga aatagagcat atttagtatc
     1141 tcctccactt cttaaaatac caattataac caatgtatta aaagatttaa gagccattag
     1201 tattcccatt ataaagaata tcttagttat atcagaagct aagctatcag aaacactaaa
     1261 catttttaat aataatggta tatttaaaat taaaataatt ccaagtatta aaccagctga
     1321 aaatacaagt atagaaaact ttttagcata ttcaatggct cttttaatat ggtcagctcc
     1381 aagttcattt ccaagcataa tagatgcacc agatgcaata catacagctg tcattatgaa
     1441 gaaattacct gtactggttg ctatctggct agctgctata gcagaagtac cagctcttgc
     1501 atatgcaaca gaatacagga cagttccaat tgcccataca gagtcattta caaatatagg
     1561 aaagcttttt gatgaaaaag attttataaa aattttatca atagctttta gattttttag
     1621 accaaacttt aatatatagt cttttttata aaggtaaaca taagtaatca ttaaaattaa
     1681 ttcacatatt ctagcaataa cagtagctag agcagcacct tttacaccca atgcaggaag
     1741 accgaagtta ccaaatataa atccataatt taaaataaca tttgttacaa gtgcaaatgc
     1801 actacaaatc atacctaact taggatttct aacacctctt gaaccagtac taaatacagt
     1861 acttacagca attaatggat aactaaatac tgcaatacta aagtaatcta tacaaagttt
     1921 taccacctca gaatcatacg aaaatatgtg tataattggc tttggtgtta gtaaagcagg
     1981 aataacaaat acaaaactta aaacaattgc caatacacaa gtaagacctg tgacttttct
     2041 tatattactc acatccttct ttccataaaa ctgtgaaata aaaactccag cacctcctgt
     2101 gataccagat aaggacatat taaaaagaaa gaaaaattgg tttgcaactc caactgaagc
     2161 tacagatgtt tcccccaaac tacttatcat aattgtatct attacattta cagaagtaga
     2221 aattaagttc tgtatgataa taggtataca taaagataga agtattttat aaaatctttt
     2281 attttcgtct tttaaagaaa atagttcttg caaataatcc tctccttttt acataaattc
     2341 ttcccactca tcatatagag aggcaaggtt attttctaaa ttaatttttt cttggctaac
     2401 ttctttagct ttatctggat tagagtatac ttcttcttga cataaaagta tatctaattt
     2461 ttcaatttca atctctaact tttcaatttc tttttctata ttttgtcttt ttattctatt
     2521 tttcttttct atttctcttt gttctctctc ttttcttttt tcatctttta tttgagttct
     2581 agttttttct tctttttctt ctataatact catctcttgg atttgccttt ttttatctat
     2641 ataataatca taatttccca gatattcagt aattccattt tcatctaaaa ctaaaatttt
     2701 atcaacaaca gtatttagaa agtatctatc atgtgatatt gtaaatatag tcccatcata
     2761 attagttaat gcctcttcaa ggacttcctt agaatcaata tctaggtgat tagtaggctc
     2821 atctaataac aataagtttg catttgatag tataagttta agtatggcaa ctctagctct
     2881 ttctccacca ctcaatgtag aaatcttctt aaaaacttct tcatctacaa ataaaaatgc
     2941 ccctaacata tttctcaaag tagtttgagt aagatgagta ttattttccc aaatctcatc
     3001 aattattgtg ttatctaaat taagagtttt ttgttcctga tggaagtagg aaacatgtac
     3061 attagttcca aatttaatat tgccactaag aggttgtagt tcattagtta ttattttaaa
     3121 taatgtagat ttgccaacac catttgcacc tataagtgca actttttccc ctctatatat
     3181 atctaaatcc aagtctttaa aaagtattct ttctccataa cccatagata catctctaat
     3241 ttgaagaaca tcattaccac tctggacaga aggcgtaaat tgtatacgag cttttttcct
     3301 ataagcttct ggtttatcta aaacgtctac cttgtctaat gctttttctt tacttcttgc
     3361 acgctttagg tgtttttctc taccataagc ttttagtctt tcaattgatt cttcttgctt
     3421 ttttatttct ttttgttggt cttcaaattt cttaagctct agttcttttt ctattttaga
     3481 taactcaaca aatttagagt agttaccatt atatacttta agttttttgt tgtgaacttc
     3541 aaaaattcta tttacggatt ggtctaagaa atatctatca tgagatatta acatgacagt
     3601 ccctttatat tgttttaaaa atacttctaa ccattctatt gcttcagagt ctaagtggtt
     3661 agtaggttca tcaagtaaca atagagttgg tttcttaaga agtaattttc ctaaaagaac
     3721 tctagttttt tcaccaccag aaagtatgct tattggctta tccatatcat tgtcactaaa
     3781 tcctaatccc tttagaactc ctttggcttc agatttatat ccatatccat ttaaatctga
     3841 aaataattct agtttatgtg aatattcatc catgattttt tctataattg gagagtttgt
     3901 ttttgtactt tcttcagata ttttaacctc caattctctt aaataggatt ccatttctat
     3961 caaattttta aaaacttcta gtacttcttc caaaatagta ttatccgaat aaaaattggt
     4021 attttgttct aaatatccga tttcacaatc tttagaagtg taaatatctc cactatcata
     4081 tccataaatt cctgaaatta ttttaaataa agtagttttt ccagtaccat taacaccgat
     4141 tataccaatt ttatcgcctt catttactgt aaaactaata ttttctaata tagaatctat
     4201 accaaaactt ttatttaagt tattacatga caaaacaatc ataaatttct acctccttga
     4261 actatctaaa attataatgt tttgatataa tataatcaag gttatatgta ttagttttga
     4321 aaaagaaata ttttattgtg aatcaaacaa aaaagaggac acttttagga ggtgaagatg
     4381 ttgggaaata aaaatatatc aatggcagtt ataagaaggc tcccaaaata tcatagatat
     4441 cttggagact tattagatag ggatatacaa agaatatctt ctaaagaatt gagtgatata
     4501 atagggttta ccgcttctca aataagacaa gatttaaaca actttggtgg atttggacaa
     4561 caaggatatg gttataatgt agaagctctt catactgaga taggtaaaat tcttgggttg
     4621 gatcgaccat acaacgcagt tcttgtagga gcaggtaact taggacaagc tatagccaat
     4681 tatgcaggat ttagaaaagc tggattcgag ataaaagctt tatttgatgc aaatcctaga
     4741 atgataggtt taaagataag agagtttgaa gtattagatt cagatacttt agaagacttt
     4801 ataaaaaaca ataatataga tattgctgta ttatgtatac ctaaaaatgg agcacaagaa
     4861 gttattaata gagttgtaaa agctggaatc aaaggtgtat ggaattttgc acctttagat
     4921 ttagaagttc cgaaaggtgt tatagttgaa aatgtaaact taacagaaag tttatttacc
     4981 ttatcgtatt taatgaaaga aggaaagtag acaacttaaa catattaata atgaacagtt
     5041 gtaaagagta ttgagaaagt cagaagattt aatattaaat cctctggctt tttgaaatat
     5101 taggataaaa atttaaataa tgtatggaaa taaacaatat taaggagagt ggtttttgtg
     5161 gaggaattat ggaaaaaggc aattgaattt catggtcatg aatgtccagg attagctata
     5221 ggatttaaag cagcacttgc agcaagagaa tatttaggat gtaaacagtc aggagatgag
     5281 gaaattgtat gtatttctga aaatgatgct tgtggaatag atggtataca agtcgtgcta
     5341 agttgcacaa tgggtaaagg aaatttacta cttaggatga ctgggaaatc agtatatcat
     5401 ttctttaata gggaaaatgg aaaatctata agaatatatg taaagtcaaa gccatttcaa
     5461 atggatagag aaggatacaa aaagtactta ttagaaagtg attttgaaga aatatttgag
     5521 attacagata ctaagttaag acttcctgaa aaagcaagaa tatttaaatc tcttaaatgt
     5581 gaagtgtgtg gtgaatttgc atctgagcaa tatataagga ttgaagaagg aaagaaagta
     5641 tgtcttgatt gctttaataa atatgaaaga ttttatgagg agtattaaaa ttataaatta
     5701 gattaaagtt aaaagtatta gatatgtgct aacagtattt taagatgaat taggtagcaa
     5761 cataataaag tatataaata atattaattg aatcatacat aattaaaaag aggctgatta
     5821 gtatttataa aataaaatca gtctctttat gaataacgaa ttattattct ggttgaggtg
     5881 catctacagg acaagctcct gcacaagaac cacagtctat acaagaacca gcatctataa
     5941 catatgcgtc gtctccagct gatatacagc taacagggca ttcagcctca caagcaccac
     6001 agcttataca agcgtcagta attttatatg ccattttgaa atcctccctt ttatatgtat
     6061 tgtaattcaa taacattata acaaatatta ttgaatataa caattaaatt aattctacaa
     6121 caaaaacttt attatgatat tcttgtttta aagttttaca ataaagttta atctgcttat
     6181 atttttattt attttaaaga agtttatttt aaaaataaaa ttaaatttaa aaagttatgt
     6241 attgattata tttaaaaatg ttatactcta aaaaagtata ttttatttaa aaatttatta
     6301 atacaaagga gatttactat gaaaaataaa ttagtttaca tatgtattat gagtctattg
     6361 ctatttgtag taggatgttc taataatcca aataaggaaa gtaccattaa aaaagactct
     6421 aagaataacc aaagccaagt taaagaagaa aaaagagaac ctgtgaaaaa agatataatt
     6481 ataagtttcg ctggtgatgt aactatgggg aactataaag gttcatcata ttatggcagt
     6541 tttgaccatg aatttaaaag acaaggagaa gattacaatt attttcttaa aaatgtaaaa
     6601 cctgtatttg aaaaagatga cttaacagtg gttaatttag aaggtccact tactacagcg
     6661 tcaaatgcaa aagaaaaaaa atttgcattt aaaggaaagc ctggatatgt aaatatttta
     6721 aaatctggaa gtgtagaggc agtaagtatt gcaaataatc attcagaaga ttattttgaa
     6781 gaaggaatga aagatacaca gtttatattg gacgagaata aaataaatta ttttggatta
     6841 gggaaagatg ctgttgtaga tgtcaaagga attaaagtgg gtctattagg gtataatgga
     6901 ttatcaactg aatataatga aaaaaattta aaacaaatgg aagatgatat taagtcctta
     6961 aaaaagaaat cgaatgttgt tgtagtgtac tttcattggg ggatagaatt agattattat
     7021 ccagataaaa aacaaaaaga ttttgctcat tatgctatag acaagggagc agatttagtt
     7081 atggggtctc acccacatgt gattcaagga atagaaaagt ataaaaataa gtatatagct
     7141 tatagtctag ggaatttttg ctttggagga aataagaatc cttctgatac agatagttat
     7201 atatatcaac aaacctttac tttttcagat aataaattaa cttcaattaa agagccaaat
     7261 ataataccaa cttcaataac atctagtaac tccagaaata attatcaacc aaaaatattg
     7321 gatggaagtg agaaggatag agttttaaat aaacttgaaa aaataagcaa agatttaaat
     7381 aaataaaatg taaaaaaaaa taaatatata tatttatttt aataatttat attttgttta
     7441 gggtatggta aatcgtggta ttaaataagt agattttaat agttaaatta tagtcaatta
     7501 taataaagct atttaatcta cttttttaat ataaaaatat aagggggaat ttgtaatggc
     7561 ttgtaacact tgtaaaatgt gcgaaagtgc agacaagaaa ttagaaagtt ttgtagcttc
     7621 aaaggatgtt gaaacagcat ttcatagaac agaagatcag aaagttaagt gtggttttgg
     7681 acttcagggg gtttgttgta gactctgttc aaatggacca tgtagagtaa ctcctaaatc
     7741 accaagaggt atatgtggag cagatgcaga cactatagta gcaagaaact ttttaagagc
     7801 agtagcatca ggagcagctt gttatttaca tgtggtagaa aatatagcta agaatttaaa
     7861 aaatgttgga ataactaaag gtgttgttaa aggagaaaaa acattaaatc aattagcaga
     7921 gatgtttgga atagaaagtg atgaaaagta tgataaatgt ataaaggttg cagacaaagt
     7981 tatcaacgat ttgtataaat caagagatga taaaatggaa ttagtagaaa aaatagctta
     8041 tgcacctaga gtgaaaaagt ggaaagagtt aggtataatg cctggtggtg caaagtcaga
     8101 agtttttgat gcaatagtaa aatcatcaac aaatttaaat agtgacccag tagacatgct
     8161 agttaattgt ttgaacttag gtatatcaac aggattatat ggtcttacac taactaatct
     8221 tttaaatgat gttatgttgg gagaaccagt tataagaatg gctcctgtag gatttaatgt
     8281 aatagaccca gactacataa atataatgat aacaggccat caacattcaa catttgcaaa
     8341 tttccaagat agattaaaag atgaagatgt tataaaatta gctcaatctg ttggtgcaaa
     8401 aggctttaag ctagtaggat gtacatgtgt tggtcaagat ttacaattaa gaggagaaca
     8461 ttatcaagaa gtatttgctg gacatgcagg taacaatttt acaagtgagg ctgttttatc
     8521 aactggagca atagatatag ttctttcaga atttaactgt actataccag ggcttgaacc
     8581 aatagcagat aaatataaag taaaaatggt ttgtttagat gatgttgcta aaaaagcgaa
     8641 tgcagaatac ataggtttag acagaagtaa attagatgaa cttagtaaca ctttaataga
     8701 aaaagcattg gagtcttata aggagagaag aggaagtatt gaaatagata taccaaaaga
     8761 ccatggattt gaacaatctt taactggtgt aagtgaaaag aacctgaaag cgtttttagg
     8821 agattcatgg aaacctctta ttaatttaat tgcagaagga aaaattaaag gtgttgcagc
     8881 tgttgtagga tgttcaaata tgacagcagg aggacatgat gtaaatactg ttgaacttac
     8941 taaagaattg attaaaaaag atataatagt actatctgca ggatgttcta ctggaggatt
     9001 agaaaatgtt ggtcttatgt cacctggagc agaagaatta gcaggagaaa acttaaaaga
     9061 agtatgtaag actttaggaa taccaccagt attaaacttt ggaccatgtc tagctatagg
     9121 aagactagaa atagtagcaa cagaattagc agctgaactt ggaattgacc taccacaatt
     9181 accattagtg ctttcagctc cacaatggtt ggaagaacaa gcattagctg atggagcgtt
     9241 tggtcttgcc cttggcttac ctcttcattt agctttacct ccatttataa caggaggaaa
     9301 attggtgaca gaagtattaa cagaaaaatt aaaagactta acaggaggac atgttatagt
     9361 gaatccagac cctaaatctt cagctaatca attagaagaa ataataataa atagaagaaa
     9421 aaatttaggg ttaaaggatg tggaatgcaa tgcatagaat ttttataaat aaagatttat
     9481 gtacaggatg taagagctgt gtactagcat gtatgctaaa acacaataaa gattatgaca
     9541 tgtacactct tgatttagaa aatatagata atgatagtag agggcatata gaattagata
     9601 gtagacataa taatccagtt ccaattcttt gtagacactg tgatgaacct gaatgtgtat
     9661 tagcatgtat gagtggtgca atgcataaag atagtgaaag tggaatcgtt tcatatgatg
     9721 aagagaaatg tggttcatgt tatatgtgtg taatgtcttg tccatatgga ttattaaagc
     9781 cagatgatag aagcaagcag aacatactta aatgtgattt atgtaaagat gaggagtatc
     9841 ctagatgtgt agctaattgc ccaagtggag caattgaatt acagaaggag gaaaatgatg
     9901 aattatgtag tgttaggggc tagtgcagct ggtataaatg cagtaaaaac attaagagaa
     9961 ttagataaag attcaaatat agtagtaatt tctaaagatg aaaacgtata ttcaagatgt
    10021 atgttgcatc atgttatatc tgaacacaga actttaaaac aaataaattt tgttgatgaa
    10081 gattttatgg agcaaaataa tgtaaaatgg attgcaggta agactgttaa aggtatagac
    10141 ataaataaaa aggtagttca gacagaagac attactgtaa attatgataa acttttaata
    10201 gctacaggtg catcttctgc tattcctcct ataaaaaatt taagagatgg aaattttgta
    10261 tattctgtga gaaacataga tgatatttat aaaataaaag aaaaagcaca aaattctaaa
    10321 aatgtagtta taataggtgc tggtttagtt ggtatagatg cattagtggg attatttaaa
    10381 tatgagcagt taaatatttc tgtagctttt atggaaaagt acattttaga tagacaattg
    10441 gatgaatata cagcatcagt gtatgaaaat aagttcaaag aaaaaggtgt aaaattttac
    10501 ccaagtgcat caatacaaga aattgtattg gataacagta aaaatgttac aggtgttgca
    10561 ttttcaaatg gtgaagtttt agatgcagac atggtaattg tagctacagg ggttaaacca
    10621 aatgctgact ttttagatgg aacaggaata gaatatgata gaggtataat aatagatgat
    10681 atgtgccaaa caacacaaaa agacatatat gcagcaggag atgttgtagg taaaaatgct
    10741 atttggcctc tggcagtaaa gcaaggaatt gtagctgcct ataatatggt tggaaaagat
    10801 aagaagatag aagatgaatt tgcttttaaa aacagtatga atttcatgga tataccaact
    10861 atttctatag gaatgaatac acctgtagat gatagctata aagtattaac cagacatgga
    10921 attaatgatt ataaaaagtt tgtttttaaa gataatgtaa tctatggagc agttatacaa
    10981 ggagatattt catatgtagg tgtattaact tatttaataa aaaataaagt tgaaatatat
    11041 gatttagaaa ataggatatt tgatgtatgt tatgcagact tttttaatat aaaagaaaat
    11101 ggagaatttt gttatagtat atagtatata cgtgaagtaa ggtttataaa tacagtaaat
    11161 caataaatag agttattcta aaataagaaa aatgacaaat cttatttaga aatagctcta
    11221 ttttttgcaa ttaaatttaa attatattca atttgtaaaa tattattttg aacaattata
    11281 catatactct ctagttagag gtaaatcatt ttttatacct ttagtgaaaa gtatttgatg
    11341 tatatctata ataccagtgt tgaaagcagc agcacaagaa caaaggtata aatcccacat
    11401 tcttataaac ttatcatcaa acatttcttt aatctttgga agattctcag agaaattttt
    11461 ttgccagtat agtaaggttt ttacataatg taatcttaga ctttctacgt ctatagtatg
    11521 atatttgtaa tcactacaaa tatgtatcat ttctcttagg ctaggaataa ctcctcctgg
    11581 gaaaatatat ttttttatcc aagggtctcc ataagattcc tgcaatccac ttatatagtg
    11641 aagtaaaaac aatccaccat cttttaaaac agcatttacg tttttaatga aaagttcata
    11701 gttttctcta ccaacatgtt caagcatccc aacgcttaca actctatcaa acataaggtc
    11761 tgattttttt aattctctat agtccataag tcttacctca agatagtctt gaaggttctc
    11821 ttctttaatt cttgcgttaa attccttaaa ttgctcttcg ctaagtgtaa ttccaacgcc
    11881 gtgaatttta tatttttttg cagcttctat tagtaaaaat ccccaaccac aaccaatatc
    11941 gagaaggctc ataccttcct ctaaatttag tttagttaat atgtggtgaa ctttattgac
    12001 ttgagcatca taaagagtat cattatcatt tctaaagtat gcacaagaat aactaagtgt
    12061 cttatctaac cataagctat aaaaatcgtt gccaatgtca tagtgggcat gtatttcttt
    12121 cttttgatgt ctcattgaat ttgatgagtg caatagatgt tttacagctg aattatcaat
    12181 attgaatttg tctatttgtt ttaaaagtag atttaaagtt aagaataaat ctccctcaac
    12241 ttcaatgtct ctatttatgt aggcttctcc aagtgctaaa gatgtacttt ttaatagttc
    12301 agacttgcta atatcattat ttactataac tttgaactga ggggagccct ctccaattag
    12361 aaattcttcc tcatctttaa gcctaactag aaatggtgtt tcaccaaatt tctctaaata
    12421 gtcttttaaa aaattttttg taatattcat attaccagct ccttctaatg taaatccagt
    12481 aagtttccct gcttaaaata tattatagtc ctttttttaa aaaagtaaaa ttttttcaat
    12541 aaatttttta tttaaaggaa atttattttt tataaagaaa tttcatgttg tagtatattt
    12601 tttgcttata aattttggta ctggatataa tattaaactg ttaatgatat aataaattta
    12661 atctataaag taaataaaat tttgtaataa atagttaaag ctattttata aggagatata
    12721 tgatggaagt atatgctttg gttgggtcaa gtggcacagg gaagagcttt aaggctttag
    12781 agttcgcata tgaaaatgat atagaatata taattgatga tgggatttta atatacaaaa
    12841 acaaggtttt agctgggata tcagcaaaac aagcaaatac tactatagaa gcagttaaaa
    12901 gggctatttt ttataatctg gagcatagac aagaagttag agaagcaatt aaaaaagaaa
    12961 atataagaaa aattcttatt attgggacat caaaaaaaat ggttaatcaa attgtagaga
    13021 gattgtcaat tggaagggtc tataagttta taaatataca agatataagt actaaatatg
    13081 agatagaaat agcaaaacaa gctagaaaag aaggaaatca tgtaattcct gttccagcag
    13141 ttgagataaa aagtatggca agtggtctta gtataaattc tttgaagaga ctttttagaa
    13201 aaggaaataa taggaatatg gtagttttag aaaaaacaat tataagacca acttttagtt
    13261 atataggaaa gttttatatt agtgctgatg taattaaaca gattattgaa tatgaagtat
    13321 acaactttgg aagcattgat agaataaata aaatcaatat agagaattgc aataatttta
    13381 tgaatatttt tgtaagtata aatatcaatg atttagaaac tataaaaaaa attgaagata
    13441 tacagcagac aataaaaaag tctattgaga aaatgacttt agttaatgta caaaaaatag
    13501 atattaacat tcataaaatt aaaaaaataa acttcctcca atgttaaaaa ataaactgag
    13561 aaaatgatat actaatttgc aataaagtgt gctataatta aactgtaaat ttaggaaatg
    13621 gttttttcta aatggagtat acataattat aacgtattta taagggggct ttcaaatgtc
    13681 aggaaaagat gtaaatgtct tcgagatggc gcaatctcaa gtaaaaaatg catgtgataa
    13741 attaggtatg gaaccagcag tttatgaatt attaaaagaa cctatgagag ttatagaggt
    13801 ttcaattcca gtaaaaatgg atgatggttc tataaaaact tttaaaggat ttagatcaca
    13861 acataatgat gcagtagggc caacaaaagg tggaataaga ttccatcaaa atgtttcaag
    13921 agacgaagta aaagctttat ctatatggat gactttcaag tgttctgtaa caggtatacc
    13981 atatggtgga ggtaaaggtg gaataatagt agatccatca actttatctc aaggtgaatt
    14041 agaaagatta agtagaggat acatagatgg aatatataaa ttaataggtg agaaagttga
    14101 cgttcctgca ccagacgtaa atactaatgg tcaaataatg tcttggatgg ttgatgagta
    14161 caataaatta actggacaaa gttctatagg tgttataact ggtaagccag ttgaatttgg
    14221 tggttcttta ggaagaacag ctgctactgg atttggtgtt gctgttactg caagagaagc
    14281 tgctgctaaa ttaggaatag atatgaaaaa agctaaaata gctgttcaag gtataggaaa
    14341 cgttggttct tatacagttc ttaactgtga aaaacttggt ggtactgttg tagctatggc
    14401 tgaatggtgt aaatcagaag gttcttatgc tatatacaat gaaaatggtt tagatggtca
    14461 agctatgtta gattatatga aagaacatgg taacttatta aacttcccag gagctaagag
    14521 aatatcttta gaagagttct gggcttcaga tgttgatata gtaataccag ctgcattaga
    14581 aaactctata actaaagaag ttgctgaatc tataaaagct aaattagttt gtgaggctgc
    14641 taatggacca actactccag aggctgatga agtatttgct gaaagaggaa tagttcttac
    14701 tccagatata ttaactaatg ctggtggagt tacagtttct tacttcgagt gggtacaaaa
    14761 cttatatgga tactactggt cagaagaaga agtagagcaa aaagaagaaa tagctatggt
    14821 taaagcattt gaatctattt ggaaaatcaa agaagagtac aatgttacaa tgagagaagc
    14881 tgcttacatg cattcaatta agaaagttgc tgaagctatg aaattaagag gatggtacta
    14941 agatttactc ttaataaata ataggatata attatttaag atataaaggg gctgtacata
    15001 gtacagccct taaattatgt ggcttgcaat gaagtaagct atttttgttt taacttataa
    15061 ataacttgat aaattatgta atttagaatg tattttttac caccacatga ttacaaatta
    15121 gaagagttag attagatttt tagacatgaa cttatgcatt ttaaaagcaa agaccttaat
    15181 ttaaagtatc tagtattatt tttaaaaata gtatattggt ttaatccatt tatatatata
    15241 atggaaaaat atatggattt ggattgtgaa ctttattgtg ataagagagt tttaaaaaat
    15301 tgtactgtac aacaaaagca agaatatgtt ctaactattg taaattcaat gaaaagaagt
    15361 acaaattttt caaataaatt tgtagctgga ttaaataacc aatctgatat tagaaaaaga
    15421 gtaatgaaca tgttcagtga aaaacataaa aatggtatct taatggcttt gattataagc
    15481 ttgttttctt ctattacatt ttttaaattc gattcaacta gtattattga agagaatgat
    15541 ttcttagaga ggttaagata tacgtttgaa ggaaggcaag aagatatgtt tgtaacaata
    15601 gattttacat atgcagatgc acctataaaa cttagaaaag agcatgaaga aaactgtaga
    15661 gtcaatggaa tagtaccaaa agattcagat tcaatagaaa ttattcctag attttataaa
    15721 gattgtatgg atttaaaaaa ataagttaga cttaatattg atgttgatat tatgaatttt
    15781 ttatatttaa gcaattgaaa attttattat agattcaatt ttatatgtgt ttaagtatga
    15841 aatttataga tagttgaaat aattaaatat gattgatgca taggaatcat tactaagcta
    15901 taattaatta taggggagtt taaataaatt atgagttaca caattataaa atgataaaaa
    15961 tagttatctg ttacaaaaaa tgtatctttt taattaataa agataatatg aaaacttaaa
    16021 aggcaaataa acttaaacat aaaatactct taaataagat aggagaaaaa tgtatgtcta
    16081 actttattct aaatgggatt tttagaacag ttatagtaag tagtctaagc attcttatga
    16141 tattgatttt caagaaaaat gtatttaaaa gatttagcaa aaaatttaat tattatatat
    16201 ggatgatagt tgttattaaa ttatttttac catttacata ttatactttt acaataaata
    16261 tcttgagaag taaaaaacac attaatatta ataacataaa tttagaggga tttaataatg
    16321 tttcaactat aagtaataat attatattgt acacttggat tataactgta gtagtttatt
    16381 taatttacac tatatttaaa tatataaaac ttaaaaattt aataaatgac ttatcttatg
    16441 atgttgatga tagagagatt gtaaatcttt ataaaaatat attagaagaa tttaatataa
    16501 caaaagatat aaaactcaaa tactcttatg aagttgaaac accagcattt tttaattcat
    16561 gtgtactttt gccaccacat gagtataaat tgaaagagtt agactggatt tttagacatg
    16621 agcttatgca ttttaagagt agggaccttt atttaaaata tgtaatcctg tttttaaaaa
    16681 cagtatattg gtttaatcca tttatatata taatggataa acatatagat ttagattgtg
    16741 aactttattg tgatgaaaga gttttaaaaa atcgaaattc agaggaaaaa aaggattatg
    16801 ctttaacaat tctaaatgca atgagaaaag gttcaaatac ttcaaataaa tttatagctg
    16861 gacttcataa gcaatctgat attaaaaaga gagttatgaa catgtttaat gaaaagtaca
    16921 agaatggtat attaatggca ttaactttat gtttattatc ttctattact tttttgaagg
    16981 ttaattcaac tagtattgtt aatcttaatg tattgccaaa aggaatggaa gaaaaagatg
    17041 ttactaatag tgcaattgtt acaatgatag aatttacata tgcagaagct cctaaaagta
    17101 tgagagaaag atataaaata aattgtgaat tcttaggttt aatacctaaa gactctgata
    17161 aaataggtgt tggtgtagaa tattatgaca gtctattgaa tgattaaata aatattattt
    17221 taacagatat taattataaa gttttgaata gtaatttgtt gagaaataaa tatatcctta
    17281 taaaaataga tacttatata ccaagaataa aaaatagtta agatagtaca caaggatata
    17341 cttataaaga acttaaataa gtgaaataaa ttattaatta taaggtttat aattttaaaa
    17401 aattagataa attcaggtgt aaaatactat aaaacacaat tcggaaaagt gtatgttgaa
    17461 tttcatttaa aatggaattt caaagttgct atagtaagta gtttaagcat tcttcttata
    17521 ttaatctttg agaataatgt atttaaaaaa gttagtaaaa aatttaacta ttgtatatta
    17581 atgatagttg ctattgatat attatctaaa aaaattaagt atgaaaagat tactgctagg
    17641 acaatctttt catacttaat ttttaatatt tatattctcc aaaattttca tctttttaac
    17701 ttagaatttg agaatcacta ttaggaaata ggctttgatt tatgtagggt taaaaatttc
    17761 acagaatatc taactttata ctaaatccat caaaaaatat acgccataca aaagcgcata
    17821 aaaaaacaca taaaacaata tttatgcgca ctttaacctc gaatggtaca aaattcttta
    17881 cttttacaga cccatattat ataattaagt aaataatgta tatttaggtg acatattgga
    17941 taagctaatt tatttatttt attaatataa taatactata aaagttatat aaagtggttt
    18001 acaaaaaagt tacagataga gcttttatta atgtattgtg tattagtatt ttatccttag
    18061 gtacacttca cctacaaaat agaatcataa gataattatg ggaaaatttt aggaggttta
    18121 tcgtgaagaa aaagatatta ataccagtat ttgcatcagt tatggcatta tcagtaagtt
    18181 caattgtaaa tgcagatgaa gtaaatgatt catctcaaaa taaggatgat aaaacaaata
    18241 ctgaattaaa tttaggtgaa tataaagaag taaaatataa agttgcaaaa ataaaagatg
    18301 gagtagctat aaagataaga gaagaaggtc aagttcaaaa catagcttat tctggagatg
    18361 aatttacggt tttaggaact caaggagaat gggttaaggt taaagttgaa gatggcgaag
    18421 gttggttagc tactagatat gtagatatat ctgaaggtgt aggatatact aacgctgata
    18481 aagtaaactt aagaaaagat aagagtgaaa gttcagaagt aattgaagag ctggaaaaag
    18541 gaagttcttt attggttttg gaagataatg gagattggtt aaaagttaaa gatggggaaa
    18601 cagaaggata tgtaaaatca tcttatatat ctgataaagc tcctgtaata gaagagccac
    18661 aagtaaaccc aagtattgac caaaatgtag attctacaaa taataatcaa caaaacaatg
    18721 caaatactaa tcaacaaaat aataattcaa atgtgccaac agctaactct aatgcagttc
    18781 aagctgtact taacttggca tattctaagc aaggttgtcc atatgtttgg ggagcagaag
    18841 gaccaaatac ttttgactgt tctggattta cacaatatgt gtatagaaat gcagtaggaa
    18901 agaatatacc aagaacatct aaagcacaat ctaaatatgg acaaactgta agtaaagcaa
    18961 atttacaacc aggagactta gtattcttca caactaatgg ttctggttct gttagtcatg
    19021 ttggaatata tgtaggtggg ggtaatatga tacattcacc atcaacagga aaaacagtta
    19081 gtgtaactag tataaattca tcatactata cagcaagatt tgttacagca aaaagaatat
    19141 tataatcggt ttgtaatatg acaaattgat aaatacataa atatatataa acgctctata
    19201 ttatatttaa tttaatcatg gaaacaaaaa atgattatat tttaaatgta ctatagagcg
    19261 tttttgtatc actttaaatc taatcaagat tcaagttaat atgactgtta aatagggcct
    19321 tttcatatga tgattatttg cgcaatccct tgacaggata gggcaaaggt ggtaagctac
    19381 taacagtaca aaaatacttt taattttagt tcagagaggc taaaaaagga ggacgaaaga
    19441 tgttaaaatc aagaaattta atccaaccag aagacttttc aatagaagaa atagatgaaa
    19501 tattagaatt agctcaaaaa ataattgaca atccgtcaaa atattctcgt atatgtgaag
    19561 gaaaactatt agctacatta ttttatgaac catcaacaag aacaagatta agctttgaat
    19621 ctgctatgaa cagattagga ggacgtgtag taggcttttc agagccaaat tcatcctctg
    19681 catcaaaagg agaaactcta ggagatacaa tgaggatagt atctggttat gttgatataa
    19741 tagctatgag acatcctcaa tcaggtgcag cttcagaagc agctagatat acggaagtgc
    19801 catttataaa tgcaggagac ggcaaaaacc agcatccaac tcaaacactt acagacttac
    19861 ttactataaa atcattaaaa gtaactttag aaagccatac aataggatta tgtggtgatt
    19921 taaaatatgg aagaactgtg cattctttgg ttaaggctat ggcaagatat aaaaatacaa
    19981 agtttgtatt tatagcgcct gaagagttaa aaatgccaga ttatataaaa gaagctataa
    20041 agggacatgc atattatgaa actaataatt tggatgatgt tataggaagc ttggatgttt
    20101 tatatatgac tagagttcaa caagaaagat ttgaagataa atcagagtat gaaagactta
    20161 aaaactatta tattttaaat aaagctaaat tagaaaaggc atctaaagat atgttagtaa
    20221 tgcatccatt accaagagta aatgaaatag acatagatgt agatagtgat gatagagctg
    20281 tatattttaa acaagctaaa tatggaatgt atgttagaat ggctttaata ataaaacttt
    20341 taggtataaa tgaagactaa tagttatcat ataatagtaa aacaaaggag attttgggat
    20401 gtataaaatt ctggaaaata tatatatagg cgaagatatg tatagaatga aagtaaaagg
    20461 taattttgaa ggtaaaatgg gacaattcta tatgttaaga gcatgggata cttatccagt
    20521 actttcaaga cctataagta tacatgatat agatgaagaa gggataactt ttctttataa
    20581 agtagtagga gaaggaactc aaattttgag taacctaaag gtaaatgata atataaaatt
    20641 agaaggccct tatggtaatg gatatgctaa ggttgatgga aaggtagctc tagtaggagg
    20701 aggaatcggt gtagctccac tatatttggt tgctaaaaat ataaaaaatt gtgatgcata
    20761 tcttgggttt agagaagatg ttatattaga agatgaatat aaacaagtat gtaataaagt
    20821 ctatacaaca gtaggaaata cttttgtaac agatataatt gatgttgaga aatatgatta
    20881 tatattaaca tgtggtccaa ctccaatgat ggaaaaatta gttaagatgg tagaaggtac
    20941 taaaacgaga attatggtat ctcttgaaaa ccatatggct tgtggagtag gtgcctgttt
    21001 agtatgtacg tgtaaaacta atggaggaaa taaaaagact tgtaaagatg gtccagtgtt
    21061 ctggggagag gacgtgattt ttaatgggta atttaagtgt gaaatttgga agtgtagaat
    21121 ttaaaaatcc agtaataatg gcgtctggaa cttttggatt tggaaaagaa tataatgaga
    21181 tttatgatat acaaaaactt ggtggtataa gtagcaaggg tcttacttta aataaaaaac
    21241 ctggtaacaa tggtatgaga gttcatgaga caccatccgg tatgatgaat agtgttgggc
    21301 ttgaaaaccc tggagttcaa ggatttatag actatgaatt accttttttt agtaaactag
    21361 acttagtcag aatagctaat gttggaggtg ggacattaga agactactta ttaggggttc
    21421 aaatgttaaa tgacaagcct atagacatta ttgaattaaa tatatcttgc ccaaatgtca
    21481 aagctggtgg aatggctttt ggtataaaaa atgaagtggc aagagaagtt gttcgtgagg
    21541 taagaaacat aacgaaactg cctttagtaa taaaattatc acccaatgca gaagatattg
    21601 taggaatggc aaaagtttgt gaagaagaag gtgctgatgg agtttcatta gttaatactt
    21661 ttaaagcaat ggcaattgat ataaaaaata gaagaccagt atttgaaaat gtatatgctg
    21721 ggttatctgg accagctata aaacctatag ctttgagaat ggtacatgaa gtgtgtaaaa
    21781 atgtaaatat acctgtaatg ggaatgggcg gaataactaa agccacagat gctatagagt
    21841 ttataatggc aggagctact tgtatccaag ttggaactgc aaattttatg aatcctagaa
    21901 taggtattga aataatagat ggaattaatg aatttatgga tagagaagga ataaaaagtt
    21961 tagacgaaat aagaggaatt atataaggta gaataaatag tattttaaag ataaaaaata
    22021 tagattaaat aaacaataat tttataacat taacatggag gaaaaataat atgagtaaag
    22081 tagatgtagt ggatatatta aagaaaagtg atgcattgtt ggagggacat tttttattat
    22141 cttcaggaaa acacagtaat agatacgtac aatgtgcaaa agtattaaga tttccagaat
    22201 atgctgctga ggtattaagt acagttgttg aacaaataaa agacttagat atagacttag
    22261 tagtaggacc agctatgggt ggagtaatag tttcttatga gttaggaaga caattaggaa
    22321 aagaagctgt atttactgag agaaaagaca atacaatgga gttaagaaga ggatttgaag
    22381 ttaaaaaagg agcaaagata ataattgctg aagacgttgt aactactggt aaatcaacta
    22441 tggagacaaa aagagtatta gaagccttag gtggagaagt tgtaggtgtt gcatgtatag
    22501 cagatagaac taatcatgat ataggtatgc ctatatatag tgctataaaa cttgatattc
    22561 aagtttatga atctgatgag tgtcctttat gtaaggaagg aaaattacca gttgttaagc
    22621 ctggaagtag ggagttcaag gaattaggga tgtaataaaa acttaattat ttatagtgtt
    22681 acttaaaaaa tgtaaatttt ttagagtaaa aatttgtaat ataacatata acttaaaaat
    22741 aaaaagcagt tagccttata aatgaaggtt agctgttttt tttgttaaaa atatatttac
    22801 aaaataagag atagtagcag tacaatataa gtataaggta aaagtattat atattaggga
    22861 ggggtaagta tgaaaaatca attaaatgaa aatcataaaa aggttgtatt ttttggagta
    22921 ggtgctgtag gagctacttt tgcagaacaa ttttttaact ctaaatatga ttttaaaatt
    22981 ctttgtgata atgaaagaaa gaaaagatat ttagaagaag gatttataat aaatggaaaa
    23041 aggtatgatt ttgattatgt aactaaagat gagtataaac aagaggctga ttttataatt
    23101 ataggtctaa aatataataa tttaaaagaa aatataaaag aattagatgg cttagttgga
    23161 aaaaatacag ttataatgtc tctgctaaat ggagttgata gcgaagagat aataggagaa
    23221 agatttggaa ttgaaaaaat ggtatattca tatgttacca atatagatgc aaagaaaatc
    23281 aataataata ttatacacac tactaatggg ataattgtat ttggtaacaa agataatagt
    23341 gaagatagaa aaactaatat aataaccgaa gtctttgatg atgtaaatat agaatatact
    23401 ttatcaaaag atattcaacg agatatgtgg tggaagtaca tggttaatat tggtgtaaat
    23461 caaacttcag ctatacttgg tgcaccttat ggagtttttc agagttctga gcatttaaga
    23521 gaattagcaa aatctgcaat gagggaagtt gttgctatag cacaagcaaa agacatatct
    23581 cttacagaag atgatgtgga acattcatta catagaatac tagaacattc aaaagaagga
    23641 agaacatcaa tgcttcaaga tgtggaagct catagactta cagaagtaga tatgttttct
    23701 aagaatatct gcaaacttgg aaaaaaatat aacataccta ctcctataaa tcagactttc
    23761 ttttatatga taaaagtaat tgaaagtaga ttttaaaggg tctttgtaag aaatattgat
    23821 aattattgat tttaaatttt attaatgtta tatactattt aagttactaa atatttttaa
    23881 ctcttcaatg aaaatagttg ctgcttttga taaagttata tcttttggaa atatatatga
    23941 gaaatgtctg ttgtagctgc ttccaagctc tatgacagac agctcattgt ttagaacagg
    24001 taagcttgtc actagattag agactattgt aattcctaaa ttatttctaa cagattcttt
    24061 gacagcataa ttacttccaa aaaccatcat actttttgga ataatttctt taacacttaa
    24121 aaacatatct aaataatctc tggttccaga accatcctcc ctgactatcc atttttggtt
    24181 ttgaagttta tcaaaactaa aatcttttaa taaatgactc ttgtatggaa gtgctaaaac
    24241 catcttatct tcaaaaaaat attcttgaat aaatgaaggg gaagagcaag tgccttcaat
    24301 aagaccaatg tctaaaatat aatccttaac atgagaagat acgattgatg tattttttat
    24361 aaaaacttct acatctatgt caggatactt tttagaaaat aatgctagaa aatttggtaa
    24421 aatatactct ccaatagtta aacttgcacc aatctttaag tgaccagtta tagcatctga
    24481 aacttggctt acatcatgat aagtaatatt taaaagattt aatatttctt tagctctttt
    24541 gtacaagatt tgtccacttt ctgttataaa aatggttttt tgtttaatag acctgtttat
    24601 aagcacaact ttaaaataat tttctagatt ttttatgtgt ttacttacac ttggttgtga
    24661 tagatttaaa tattccccag ctttagtaaa gtttttgtat tcaacaacag ctacaaatgt
    24721 ttttaattct tcaaacaatt ttttgtctcc tttacctaat gaaattttac attttttata
    24781 tactttctac agataattat actatatata ataaccatta aaaacattaa tcattacgat
    24841 attatatatt tattttactt atggttatta caattatata ctattgctat gaagaaaact
    24901 atattaatta taaggtaggt atattatgtt aaagaaaaaa agcagtttga cattaaaaac
    24961 tataagggaa atattaccag gactgtttgt atcagtatta gtaggttata ttagtatatt
    25021 tatttctatt ttaattccta aggtaggggc agcatcaatt tctatatttt taggtatgtt
    25081 tgtaggaaac ctatttttaa atcaaaaggt atttcaaaaa ggttataaat tttcagagac
    25141 agatttgtta tcatattcaa tagtactatt aggagcaaca ctcagtgtat ctaccttaat
    25201 agacttaaaa gtttcaggaa ttttatttat aatattgcaa atgacaataa caataatagc
    25261 tgcactttat ataggtaaaa aactaggatt tgaagaaaac tttagatttc taatggcaag
    25321 tggaaatgca gtatgtggtt cttctgcaat aggagcaaca gttccagtgg ttaatgcgac
    25381 agataaagaa aagggaattg cagtaactat tgtaaatgtt actggtatat ttcttatgtt
    25441 tttacttcca ataatatctc aatttttata tagccatgaa cttgtaaaaa cttcagcaat
    25501 gataggtgga actttgcaat caattggtca ggttgtagca agtggagcaa ttgttggaga
    25561 aaatgtaaaa gatttagcta ctatttttaa gatagtaaga gtaatatttc tagttgttgt
    25621 tgtattagta tttggacata tgaaaaatca atctaatagg gaaattcttg aagaagaaaa
    25681 ggatgagata aaaaagaaaa aagtgactat accatggtat gtaattggat tctttataac
    25741 ttgtgcactt ttttcaatga acgttatacc acaagaagta tctgtgttgt gcaaagaaat
    25801 aagtaacaaa ctagaaataa tagctttagc agcaattgga ttaaaggtta atgtaaaaga
    25861 tttagtgaaa caagggaaag aagtttcttt atatggttta tttgtaggta cagtacaagt
    25921 tgtatcagct gtagttttaa taaaaatatt tatatagcat aaaaatagta tttgtaatat
    25981 taatttgatt aattaaaata atatgatact aataatttat aatataaata aaaaatgaat
    26041 ttcgataagt ttaagtgggt ataaacttat agaaattcat tttttattta aggtaaaaat
    26101 ttaaagtaaa atattatttt acataataat aaccttataa attttgaaat tacttatctt
    26161 tgtgttaaaa taagtaaaat gcacatatta gagctaagtt tttaagtaaa taaacaaaat
    26221 gaaaatataa atattaagga gatttggtat atgaatgttt atgaaaaagg taatggagtt
    26281 atactagaag gagtaacaga ttttgaccca gtacatatat ttgagtgtgg tcaatgtttt
    26341 agatggcaca aacaagaaga tggctcatac actggagttg caaaggggag aatattaaat
    26401 gtcaaaaaag agaatgataa aatatattta aataatacta atttaaagga gtttaacagc
    26461 atttggtata attactttga tttaggaact gattatacag aaataaagaa taagctaaaa
    26521 aatatggatg aatatttaaa taaggctact gaatttggat ggggaataag aatattaaga
    26581 caagatggat gggaaatgct tatatcattt ataatttctt ctaataatag gattcctatg
    26641 atacaaagag cgatagaaaa tttatcaaga aagtttggta agtatatagg tgaatatgaa
    26701 ggtaatgaat actatgcatt cccaacacca gaagaactaa ataaggcctc acaagaggaa
    26761 ataagagcat gtcaaacagg ttttagagat aagtacataa aaagtactac acaggcagtt
    26821 atagagaata atgatgaggt atctgaatat acaaatttaa gtacagaaga ttgtagaaaa
    26881 gagcttttaa aatttaatgg agtaggacca aaagtatgtg attgtattgc attatttggt
    26941 atgcaaaaat atgattcttt tccagttgat gtttgggtta agagagttat gcaagaattt
    27001 tatatagatg aagacatgag tttacctaaa atgagaattt atggaatcga taaatttaaa
    27061 gaaatgtctg gatttgctca acagtactta ttttactatg caagagaact cggtatagga
    27121 aaataaatta agggggagaa attatgggag taataggaac aatatttctg ttctatttaa
    27181 ttatatcata tctagctgga gccataattt ctgtgattat attgcttgaa aatagagacc
    27241 ctgcaaaaac aatgtcttgg ctattgatgt ttattatatt tccaggtgta ggtttaatga
    27301 tatatgctat ttcaggtaga aatattagaa aaagaaaatt atttaagact caaaaactag
    27361 ctaataatat aaaagaaaag aaactatttg atacattaga aaagataaca gaaatagttg
    27421 aattagaaaa agaatctata aaacaaaata agcttttaag agatgaagag gatggtagtt
    27481 atagaaaaag ggtaataaat atgttgttaa agactggtat gtttcccttt actaaaaata
    27541 ataaagtgga tgtatttgta gatggaaatg aaaagtttaa aaggcttata gaagatataa
    27601 gagaagctaa agaccatatt catttagagt actttatcat caaagatagt gaaataggta
    27661 gggtgttaaa agaagaactt ataaaaaagg ctaaagaagg cattaagata agaattttat
    27721 atgatgatgt aggatgctgg agattttggt ttaatagaaa atttttccga gaaatgaggg
    27781 aagtaggtat agaaattgca gcatttttac ctacaaaatt tcctataata ggagggaaat
    27841 taaactatag aaatcacaga aaaattgttg ttattgatgg aataattgga tatacaggtg
    27901 gaataaatat aggagatgaa tatttaggca aaaatgataa gtttggatat tggagagata
    27961 ctcatattag gattaagggt atttctgtat acatgcttca aatgacattt ctgattgatt
    28021 ggtattatac gacaaaagaa gtattagtga ctaaaaatta tttcccaagt gtagggaatg
    28081 ttggtgaaag tatgatacaa gttgttgcga gtggtccaga cagtgactgg gaagatattc
    28141 attatgctta tttttctgca atatgtcagg ctagaaaaaa tgtttatata gaaactccat
    28201 attttattcc agatgaaagt ctactaaaag ctataaagag tgctgctctt agtggagttg
    28261 atgtgagaat aatatttcct aaaattgcag accacaagat agtaaatata gcatcttatt
    28321 catattttga agaaatatta agagcaggtg gtaaagttta tttatataat aaaggattta
    28381 tacattctaa agtcgtaata atagatgata aaattgcttc tgcaggtaca gctaatatgg
    28441 atttaagaag ttttatgctt aactttgagg taaatgcatt tatctatgat gaagaagtta
    28501 ttagggtaat gacagatgat ttctttgagg atttaagtca ctgtgaagaa cttaatttgg
    28561 aggtatttaa gaatagaaat atcatacaaa aaatcaaaga atctgtagca agattatttt
    28621 caccaatatt ataaaaaatt attaaaaaag gtattgaaaa ttatgtgtga ttggtatatt
    28681 ataataattg ttagcactct attagataga gtgataataa ataaaaagta tatatataaa
    28741 tctacatata taagtagtat taatttaaaa ataactaaaa acataggcga actagtctat
    28801 acttaatatt ttaggaggcg tgaataatga aaataagacc attagctgac agagtagtaa
    28861 ttaaaaaagt agaagcagaa gaaaaaactg caagtggaat agttttacca ggagcagcta
    28921 aagagcaacc tcaaatagct gaagttgtag aagttggacc aggtggaata gttgaaggga
    28981 aagaaataaa aatggaattg acagtaggag ataaggttat attccaaaaa tattctggaa
    29041 cagaagttaa gatagaagga caagaataca caatactaag acagagtgat gtattagctg
    29101 ttattgaata aatatagaat aaatttatta ggaggggttt aaaatggcta aagaaattaa
    29161 attttcagag gaaacaagaa gagctttaga agctggtgta aataaattag cagatacagt
    29221 aaaagtaaca ttaggaccta aaggaagaaa tgttatatta gataaaaaat ttggttctcc
    29281 acttataact aatgatggag taactatagc aaaagagata gaactagaag atagatttga
    29341 aaatatgggt gctcaattag ttaaagaagt agcaactaaa actaatgatg tagctggaga
    29401 tggtactaca actgctacag ttttagcaca agctataata agagaaggtt taaagaatgt
    29461 aacagcaggg gctaacccaa tacttttaag aaaaggaata caaaaagcag taacagtagc
    29521 agtagaagaa ttaaaaaatc aatcaagaat agtagaaaca caagaggcta tatctcaagt
    29581 tgcttctata tctgctggtg atgaagaagt tggaaaatta atagcagaag ctatggaaat
    29641 agtaggtaaa gatggagtta taactgttga agagtctcaa actatgaata ctgaattaga
    29701 tgctgttgaa ggtatgcagt ttgatagagg atttgtttct gcatatatgg ttacagatgt
    29761 agataaaatg gaagcagttt taaacgaccc atatatatta attactgata aaaaaatatc
    29821 taacatacaa gaattattac cagttcttga acaaatagtt caacaaggta aaaagttatt
    29881 gataatagct gaagatgtag aaggtgaagc attatctaca ttagtagtaa ataaattaag
    29941 aggaacattt gatgtagtag cagttaaagc tccaggcttt ggagatagaa gaaaagaaat
    30001 gcttcaagat atagcaatac ttacaggtgc tcaagtaata tcagaagaat taggttatga
    30061 tttaaaagaa gctgatttat ctatgctagg tagagcttca tctgttaagg taactaaaga
    30121 aagtactaca atagtagatg gttctggaga taaaaaagct atagaagata gagtaactca
    30181 aattaaacat caagtagagc aaactacttc agattttgat agagagaaat taatggaaag
    30241 attagctaaa cttgctggag gagtagctgt tgtaaaagtt ggagctgcta cagaagtaga
    30301 gttaaaagaa agaaagttaa gaatagaaga tgctcttaat gcaactagag cagctgtaga
    30361 agaaggaata gtagctggtg gaggaactgc ttttgttagt gttataccag caataggaac
    30421 actaattgag agtttagaag gagaagttaa actaggtgct caaatagtta aaaaagcgtt
    30481 agaagagcca ttaagacaaa tagctataaa tgctggtctt gaaggtgctg taattgtgca
    30541 aaatgttgtt aattctgaag cagaaactgg atttgacgca ttgaatgaaa aatatgtaaa
    30601 tatgatagaa gctggcatag ttgacccaac taaagttagt agaagtgctt tacaaaatgc
    30661 tgcatcaata gcaagtactt tcttaactac tgaagctgct gttgctgacc ttcctgaaaa
    30721 agaagatgca ggaatgccag gaatgggtgg cggaatgcct ggtatgatgt aatttaaaaa
    30781 atttaaaata taaattttaa tataaagaac tatttcgact tagattttaa actctaagtt
    30841 gaaatagttc ttttgtatat atctaatttt tgtatatcta taaattcaat acacatattt
    30901 agataatcag tatctagttt gtaataatat tttagagtag tattgttatt ttttaggtta
    30961 tgattttaga tatatattaa ttaaggtata attgttgata gagaataaat caaatttaaa
    31021 aggatgcgat aatatggact taagaaaatt gcttgaagaa gttaaaaatg aaaatattga
    31081 tatagatttt gcgttagaaa agttaaaaga tttaccttat gaagaccttg gatatgcaaa
    31141 tatagatcat catagagaac taagaaatgg gtatccggaa gttatttatt gtgaaggtaa
    31201 gagtgatgag catattttag ggattattga taaaatgaat caaaaaagtt ctaacatatt
    31261 ggggacaagg tgcagaaaag aaacttttct gaaaattaaa gaaatctata atcatgctga
    31321 gtacgaagag gcgtctaaaa ttcttaagat tcaaaatcat gatatagaga atataggaaa
    31381 aggtaaaatt gtgattgcta cagggggaac ttctgatata ccagtagcag acgaagctta
    31441 tcatacagct aagtttttag gtaatgatgt tgatagaata tatgatgttg gagtggcagg
    31501 tatacatagg cttttaaata aaagacataa aatagatagt gctagagtaa tagtagccgt
    31561 tgcaggtatg gaaggtgctc ttgcaagtgt aattggtgga ctggttgatg ttccagtaat
    31621 agctgttcca acttctgttg gatatggagc aaattttgga ggattagcag cattactagc
    31681 tatgttaaat agctgtgcat ctggaatatc tgttgtaaat attgataatg gatttggagc
    31741 aggatattta gcatcaatga taaataaact gtaaatacat tgatataaat taaacaaaac
    31801 tatataataa aatttaattt ctattatatt tttactatta aaattgagga gacatatatg
    31861 agtgaaaaaa tactttattt tgatataata agcggtatat caggggatat gacccttgca
    31921 agtttattaa atttaggtgt gcctaaggaa atttttttgg aggaaattca taaactaaga
    31981 atgagcgatg aatttaatat aaacatcagc tcgaaaactg aaaatggaat agtaggtaca
    32041 aaagtagaag taattacaaa agaaaaacat acacatagaa atttagtgga tatatttgag
    32101 gttatagata aaagcactct aaacgaaaat gtgaaatcta aagcaaaaaa aatatttatg
    32161 gtaattggag aagcagaagc aaaagttcat ggaactacaa tagacaagat acattttcat
    32221 gaggtagggg ctatagattc aattgtagat atagtaggag cttctatatt agttgactta
    32281 ctttgtgtag ataaagtttg tgctagtaca gtgtctgttg gttcaggatt tgtaaaatgt
    32341 gaacatggaa ttatacctat acctgcacct gcaactatag aaattttaaa aggtgtgcca
    32401 attaaattaa ataatgtaaa tggagaatgt acaactccaa caggagctgc aatcataaaa
    32461 gtcttgtgtg atgagtttgt agatgagctt gaattttctc caaagcaaat tggatatggt
    32521 ataggtcata agaagtttga agtaccaaat atactcagaa ctgtattagg tgaaaaaaaa
    32581 aagaagaatt aatttatgaa attagtgcaa acattgatga tatgtcttca gaaatctatt
    32641 cttatttgta tgaaaaaata ttagatgaga aagcattaga tatttataca gagagcattt
    32701 atatgaagaa gaatagacca gcaacaaaac tatcaatttt atgtaatgaa tcagatttag
    32761 aaaaatttat taaaatatta cttttagaaa ctagtacttt tggagtgaga tataatgcat
    32821 ataatagaga aattctagag agaaaatttg taaaattaga tacaaaatat ggagtggtta
    32881 cagtaaaact agggtattat aaaggaaaac tagtcaaggc tactccagaa tataatgaat
    32941 gtaaaactat agcaaaaaat gaagatattc ctataaaaaa agtgtttgct gatataaatt
    33001 tcagaataaa agaagaattt agtgaaaact tattgacata agtaataaat tttgataaat
    33061 taatattcag ccttattaaa taaaagtaaa cagaaaaaaa tatataaaat ataaactcac
    33121 tcgtatatgc tcagaaatat ggtctgagag tctctaccaa gataccgtaa atatcttgac
    33181 tatgagtgaa attattatac caaaagacct agttaagtaa atgtgtaggc tgagttaaac
    33241 tccctatgtg ttggctataa gataaaggta ttttggaagc ctgtatagta atttcacttt
    33301 tgctagaaat tatggaagtt actatacagg ttttttgtgt aaaaagattt aatataattt
    33361 agactgtatt gtgttaaaat aaatatataa aaactatatt atacaaggag agatgtgaat
    33421 ttatgaaaca tgaattagta cttgtaatag attttggagg acaatataat cagttgatag
    33481 ctagaagagt tagagaaaac aacgtatatt gtgaaatact tccatgtact gcaagcatag
    33541 aaagaataaa agaaaaaaat cctaaaggga taatatttac aggtggtcca aatagtgcgt
    33601 atttagaaga ttctccaaca atatcaaaag aaatatttga gctaggagta ccaatacttg
    33661 gaatatgcta tggtattcaa ataatgtctc atgtattggg tggagttgta agaaaaggta
    33721 ataaacaaga aaaagaatat ggaaaaacag ctataactta tggaaaatca tcattatttg
    33781 aaggaataac tacaaatagt gtatggatga gtcatacaga tttaatagaa aaagttccag
    33841 aaggatttac tatagttgca aatactaatg attgtccagt agcagctatg gaaaatgtag
    33901 aacgaaacct atatggagtt caattccatc cagaggtaga acactgtttg gaaggggaca
    33961 agatacttac aaacttctta tataatattt gtaaagtaaa aggtgactgg actacagatt
    34021 cattcataga agataaaata aaagaattaa aagaaaaaat aggcgataaa aaagctttat
    34081 gtgctttaag tggaggagtt gattcttctg ttgctgcagt tcttattcat aaagcaattg
    34141 gggacaactt aacttgtata tttgttgacc atggtttact tagaaaaaat gaaggaaatg
    34201 atgtagaaag aatatttaga gagaaatttg atataaattt aataagagtt aatgcagaag
    34261 atagattctt atctaaatta aaaggagttt ctgaaccaga agctaagaga aaaataatag
    34321 gtgaagaatt tataagagta tttgaagaag aatcaaataa attaggaaaa atggatttct
    34381 tagtacaagg aacaatctat ccagatgtta tagaaagtgg acatggaaat gctgctacta
    34441 taaagtctca tcataatgtt ggtggaatcc cagaagatgt agacttccaa gaaattgtag
    34501 aaccattaag agagttattt aaggatgaag ttagaaaaat aggattagag cttggtatag
    34561 aagaaggatt aatatttaga catcctttcc caggaccagg tctaggaata agagttatag
    34621 gtgatgtaac taaagaaaaa tgtgatatat taagagaagc tgatgctgtt tatatggacg
    34681 agcttagaaa agcaggttta tacagagaaa tatggcaagc ttttgcaaca ttaccagatg
    34741 ttaagactgt tggagttatg ggtgatgaaa gaacatatgc ttatttagtt ggtttaagag
    34801 cagttacttc ttctgatgga atgacttctg actggtataa gatgccttat gatgtattag
    34861 aaagaatttc taatagaata ataaatgaag ttgatggagt aaatagagta gtttatgata
    34921 taacttctaa gcctcctgga actattgaat gggaataaca gaaacaaaca tgttactgat
    34981 aaaaagtaca gtaaaatcaa tgatttagcg acataataat gctgaaacag ttgaattgat
    35041 attgttttga tactacaagt caaaaaaaga ctttaaaaat tagttgttaa atttgtgttt
    35101 atattttaag agcgcaggat atggatataa gtcctgtgct cttttggtgt gcaattattt
    35161 cttgggtgga attttggcag tgatagaatc aacaataaat cttatattac tttcttactc
    35221 aggaacaaaa atatttctta acttaaaaga ggctgccaat ttactaaata tttcgcagca
    35281 gcaaatttat aagattatta gagatatgaa taagaagttg gctgagtatg cttttcttgt
    35341 cattagagtc gaaatcaata agaaatattt ctttgaacaa atttataaag caaaaaagat
    35401 acagtaatgt caacatacaa agatgaaaaa agtggtattt ggtactattc tattataaag
    35461 attgagatgg ataaaggaag ataaaggtaa aaagtggatt ttcaactaaa aaagatacaa
    35521 tagcatttga gcaaaatttt agtgttaaga tttcaggttc attaacatgt tatttgaaga
    35581 tttatatgaa ttttataagt ctgtacagta agatcaaata cttggatgac aaaagaacat
    35641 atgataaaca cgaaaatatt gcttttttcg aaaagatgaa ggtgaataaa agtaagcctt
    35701 taacagtaaa aaaaggcata atatattgct caatatagag aagacctatg gaaataacta
    35761 taagcttatg taccttaaaa ctgcagaaag taaaaggact ataatgttgc cagattttct
    35821 agttaagcaa actcaaatta ttctttgaaa gtaggttatt tttctgatga tgatcttata
    35881 ttttcaaaat gcaaaacttg ctttaataaa gagatggaaa gaggcattga aaagtcggga
    35941 attaaaagga taaaactaca tgttcttaga cgtagtcaca tatacatatc tatagaaata
    36001 ggttttgtac ctgttgatat attgtcaaga gtagggtaat gagagtataa aagtatttat
    36061 agattataga catatattac caaataaaca agcaaatatg aaggataaac ttaataagga
    36121 tggggaaaaa atgaaagtac tatagtttcc gaactgttat gagatagtaa acaaaaaatc
    36181 aaaatcaaaa gaatagttgt tgataagaaa tgaatggtta gccttaaaag aggagcgaaa
    36241 gtaaaaagaa agggagaaac ataaagtaac agataaaaac cgagcaagaa aaatgactat
    36301 agtttctaga actactgaaa aagatagaac tattatattc tcaaaactaa ctttattagg
    36361 tttaaacaga caagactata tgactaacat aatcttgcat gtacctattg aagtagtatc
    36421 aactaaaaat gtaatatata aattcaaaga ggagcttaga agaatagtta aagaactaag
    36481 tagattagaa aaattttctg atttaaataa tagaagttat gaaatgctta taataataaa
    36541 cgagattatg aaagcaagta ttaaacaaga gaaaagtaca cagtaaatta ctaaatgcaa
    36601 gatgaaagta caacttggta tttcatatct gacaatatta ttttatcagg ttgtgcttct
    36661 tttttaaatg aaaggagaag aaaaccatga aaaagaaatg gtatataaac aatataccta
    36721 tagaactaat agaatataaa taatgactat tatttaaaaa tttaaaacac tagataaaaa
    36781 tgaaaatgaa aaagtagcta aaatcctttt gaggccagta acgaaaagtt caaataactg
    36841 gaacaaaaaa gaaagttgga ttaattttga aacaccagta aataattttg ggagtagtgg
    36901 ttttgataga ttatattttg taagtacaag agaggattca tttatttgtg tcagactaga
    36961 taagattgac attacacact atgattgtat tctaaaagga tttgaagata tttataaaga
    37021 aatctcctaa tcagctttag gtatacatat atttgctaaa ggaaggttta ataaccaaga
    37081 agaccatata aagatgcatc aagaaaatag gtgtatattg ctatgatgat aaatctgcaa
    37141 ggagagaaga gaagctatct tattacttta cttgcaaaat gagagaaata aactctatag
    37201 atctatcaca aaaaaaggag atgaagaacg tgaataactt gtttaaattt gattaagaag
    37261 tattagaaga atttagagac agagaacttt actatacaga aaaaggaaaa atatataggg
    37321 gaaaagaatc aactattgag atgatataga ggtataagga acaaataaat caacagctag
    37381 ctaataaaag aagtataaaa gaacaagaaa ggtaatgatt aggagcaata aaatttgttc
    37441 cttttttcct ctttaaatag agtgaacact atttttatat gcgaaaatgt agtataataa
    37501 tagcgagttt actcgtattt taaagaaaga aggaatgcaa tgaaagtaag ttataaaaag
    37561 ttatggcata tgctacttga taagaacatg aaaaagaaag aactagcaaa acttgctgga
    37621 attagcacat acactattaa taagttaaat aaaaacgaaa atgtaaccgt agaaataatt
    37681 ggaaaaattt gtttagtact tgattgtaaa gtagatgaaa tattggaatt tagtaaggaa
    37741 taaaggagac aaaatatgat taaggataat tttttacata atcaaaatgt aaaaccgaat
    37801 agagaaaaaa tagaaaaact aagaacaaat tttccagagt actttgatgg aaacggagaa
    37861 tttttgctaa atcaattcaa ggaaatgcta aaagaggaag atatcgaatt taataaagaa
    37921 ggctatgaac ttaaattttt aggaaaaacc tatgcgagat atttaagttc aactaagaca
    37981 gaaactttta tcgctccaca caataaacac aacgaaaaag atgaaaacaa aagtagtgat
    38041 aatttataca tcataggaga taacctcgat gcattaaaac atcttcttgg atcatatgca
    38101 ggaaagataa aatgtatata tatcgatcca ccatataata caggttctga cggttttgtc
    38161 tacccagata actttaaatt taatgcaaag gaactatcaa ctgccattgg aattgaagaa
    38221 gaggaagcac aaagaattat aaatttagca ggaaagagtt cacattctgc atggcttact
    38281 tttatgtatc caagacttat tttagcaaga gaattacttt caaatgatgg agtgattttt
    38341 attagtattg atgataacga acaagcaaat ttgaagttga tgtgtgatga agtttttgga
    38401 gaagagaata taattgctaa ttttatttgg aataataaat atactgtttc caatgatacg
    38461 gatatttctt atcaacatga gactataaca tgttattcga aaagtagaaa tatctttgaa
    38521 ttgaatttat tgccaagaac tgagaaacaa aataaagatt ataaaaatcg tgataatgat
    38581 ccaaaaggtc cttggaaatc aactccgtta catgcaagaa gtggaacaga atctggatta
    38641 tatgaagtaa catttgataa tggaataact tggaaggcgc cgattggtag atttccaaga
    38701 tattctaaag ataaattgct agaactatat aataatgggg agttatactt caataaaaat
    38761 ggaggcgtag ataaaaaaac atatttatct gaagttagaa aaggaataac ttgtggaagt
    38821 ttatggagtt atgatgatgt aggtcattcg catggaaata atgaagaatt ggcaaattta
    38881 attgggaaag gtatttttaa tgatcccaaa ggaacattac tattgaatcg aattttaatg
    38941 atagctacac taaaaaattc tatagtgctt gacttctttt cagggtcagc aactacagct
    39001 catgctgtta tgcaattaaa tgctgaagat ggtggaaaca gaaaatatat catggttcaa
    39061 cttccagaga taattaagga agataaacct gcgtataagg caggatatag aactatcgat
    39121 gaaataggtc gtgaaagaat tgcccgtgca gctaaaaaaa ttaaggaaga gacaaatgca
    39181 gatatagatt acgggtttaa actgtattcc cttgaaaatg taacagtaga tactcttgtt
    39241 actctcgatt attttaacaa tgacccaaag ttagaattag ataacttagt ttcggttttt
    39301 gatactgtgc attctaaggg taaagatgct atactttcaa cttggcttgc gcaagatgga
    39361 tatggtttaa ctgtgcatac taaaaaatat aagcttaaaa cttacgaagc agataaaata
    39421 ggtgactctt tatatttaat atctaaggag ataaaatcag aggatattat ggaactgatt
    39481 aagcgaattg aaaagatgga gcttgatatc acaagggttg ttgtatacgc ttcttccatg
    39541 cattttagtg agttacatga gcttaagaaa aatctaaata atctaaagaa taataaaaat
    39601 gttgaattga ttgagaggta ttaatatggg aataaaatta agtatattac ctcatcagat
    39661 ggaatgtcta gagagggttg taaaagtatt tgaagatgta agaattgaag ctagagaaga
    39721 aatttttgca aatcctatta tagatataac cagcgaaaca ctaagaaata atattcaaga
    39781 tatgcagagt aattttggag ataacagtat tccaaaagag ttaagaacca gaagagatga
    39841 ttttggtatt gatgtacgta tggaaacagg aacgggaaaa acttattgct acacaaggct
    39901 tatgtatgag cttaataaaa agtttggttt tcataaattt attctcttgg ttccaacaac
    39961 accaatcaaa gaaggaacaa aaagctttat agaatccaat tatgcaaata agcatttttc
    40021 agatctctat cctggaaaga gaataacttt atctgtgctt aatccgcaaa aaagagtaaa
    40081 aggaaagaaa aagatgtttc cgcaggcaat ttctgattat gcaaggggaa cgaggctaga
    40141 aagtggtagg ataaatgttc ttttaatgag tagtggcatg cttttatcaa aagccactat
    40201 ggatgatgat tatgatcaaa ctctatttgg ttcattttca aatccttatg aaactttaaa
    40261 agcaactaga cccatcataa tcattgatga gccacataag tttaagatag aaaacaaggc
    40321 ttacacgaca cttattgaaa gaataaaccc tcaatgtgtt attcgctttg gtgctacctt
    40381 tcctaataaa ccaaaaagca ttgataagga ctacaataat ttagtcttta acttaggtgc
    40441 ttgtgaagct tttaatcaaa atttagttaa aggtgttata acacaaatga ttcatcaaga
    40501 aaatttgaat gaaactaagg ttaagctgat ggactttaaa attaagggta aaacttgtgt
    40561 ttttagaaat gaaaaaacat taaaaagttt tactctaaca attggagata gcctgtctat
    40621 tgttgatagt gatttttatg gaataactat tgaaagaata ggaaaaacag ataacgaaga
    40681 aattaagaca ggagttatct tatctaatgg tcaaatttta gcaaagggtg atcaaattta
    40741 cgctggagtt tatgctcata catatcaaga actcatgatg aaacaagcga ttaaaaatca
    40801 tatggaacaa gaaaaaatca atttctttaa ggaacgaaaa ataaagacct tatctctttt
    40861 ctttattgat agcatttatg cttatcgtgg agaagaagga gatggaagtt taagaattag
    40921 ttttcaaaag cttttaaaag aagctctaga aaaagaacta gaatactaca aagaaactaa
    40981 agtagagatt gaaaaggact atgttagctt tctagaaagt tcgttaaaag atatctctaa
    41041 aacaaatggt ggatattttg ctgaagataa ttcagtagca gatgaagata tccaaaaaga
    41101 agttgatcag attttgagag acaaggaaag tttactatca tttaaagatg aagagggcaa
    41161 ttggaataca agaagattta ttttttcgaa atggacgctt agagaggggt gggataatcc
    41221 taatgtattt caaatttgca aacttcgttc aagtggatct gaaataagta aattacaaga
    41281 ggtaggacgt ggtcttagac tccctgttga tgaatatggg aatagagttt ccgatgagca
    41341 attttattta acttatcttt atgattgctc tgaaaaatat tttgcaaata atcttatcaa
    41401 agaggttaac agtgatagta aggtgaattt aacttctatt aagactatgt tagagaaagt
    41461 tgcaagggat agaggagtag aagaaaagca attgtttgct gcgctattaa taaatgactt
    41521 tattgatgtt gatggaaaca tcaatttaga gaaatattca gagtttattt taaattaccc
    41581 agagtttaat acaggattag aacaaaataa gattgtagat aaaaataaga aagacatagg
    41641 aacagttaga ataagaaaag ataaattctc tgaaatcaat gatttatgga ataagataaa
    41701 tcaaaaatac tatttaaagc tcgatgatat tgaagaacaa gagctttata atgctgcttt
    41761 aaacatttta aaaactgata tagctgtgca aactatggca agaacgattc agcaaaagac
    41821 tgatatcgaa gatggcaagc ttatattaaa agaggaaatt gaaggatact atgtattaga
    41881 tgatagtatt ccttataaca agtttttaca acaaatacaa aaggcaactg gtttatccat
    41941 gtcaatcatg cacaaggctt tatgcgaata taacaaaaca aagttgcttg ataaatcttt
    42001 ttttaatcat aatacattga ccaagtttat cgagaagttc cagcattggt ttgaacaagc
    42061 gttcttgaag agattttctt acaaatcatt agatgtaaat tctctagaaa cttcacttac
    42121 agatatcaat ggagagccaa aggagaagat tgttcaaggt gtagttggta ttattaaaga
    42181 cgataatctg tcagtcccag ataatttctt gtacgatgct gtggtctttg atagtgaaaa
    42241 agaaaaggag aatataaaaa atagtaatat tgatgaagta gttgtttttg ggaaaattcc
    42301 aagaagaagt gtacaggttc ctctttactt tggaggcaca acaagtccag actttatgta
    42361 tgttataaag aaagatgaag agcatgagct taactttatt gttgaaacaa aagatgtgaa
    42421 gaaagaatct tcattaagaa gagatgaaga tttaagaata gcatctgcga aaaaattctt
    42481 tggggaatta aaaaaagaag gaataaatgt ttcctttgaa aaacaactac agtctgatga
    42541 tattgtagga atgatacgaa atttattaac gaaataatgt aatcacaagg agtaaactat
    42601 gattaaatac gataaatata aagataatga agaccttata gatactttaa actacatagc
    42661 ttcagggaga ggtgtatgat ggacttgatt tagataactt tgagatagta aataaatact
    42721 atgccattga ccaagggatt gtattagaag aacttgatat gggaaatatc tctgacatgc
    42781 aaggtttcaa catagttttt gaatattata ttatttagct caagaagctg aataaggtgg
    42841 tttcattgaa ataaaaaaat tgatgaataa tatatcactc ttgatactga tttgatacta
    42901 ttcatatttg ccagtacttt ttggaataat aagtaaaaag agcaaaaaac cctatgctga
    42961 accataaatt cagcagggtg ttttttgttc acctttttat tttattttgc tatatttact
    43021 gtttggatat agatgccaac atatacctaa tactatttca atatctttat agcttaagct
    43081 acatatccaa ttgttttacc aaaataacag tttcatctat tccataatct ccagtcccat
    43141 agagagatat gtattcatcc aataaataat cactcattgg tttagtagat ggcttgaatc
    43201 cagctttttt atatgccttt actgccctta tattttttct tgatggtgca ataattagtt
    43261 cacaaatata cattgtttta tttaaaaaat ctccaagtga aataatggca tctactccaa
    43321 aacctttccc acaattagcc ttacaattca tccaaatgtc aatttctaca agagattgct
    43381 ttaaatgaaa acaagaatag ctaataaatc caactgactt tgtattactt actataagaa
    43441 aacctctgcc atcctttggt ttagtaccag tgaaaaaata ctccttataa tcttcttcac
    43501 agaattcttc ataagttgtg ataggtatat tggataatta ggtagtccag aatgagattt
    43561 tgtagtttca gactgaaaac actattcgta tacttttcgt ctatcatcta aggtggaagg
    43621 aattaaactt attttatctc cattcttcat atagttcaat atttgctggt agtgtaagca
    43681 aattctaatt tacatgtatt gtaacatatc tcaaatatat aatcactgaa tattgctata
    43741 acataataga ttcatgtaag atagtgttag aaaactcttt gatgatacta taaataaact
    43801 tgatgataaa atagacaaat tttataagta ttagatacat agaataaaat ttttacgtct
    43861 atgaaatata tagatgactt ttgtaagtta atgtattaat attgatatta tagaagaatt
    43921 gagttgtcaa tgatactaaa tcaaatattt atagaagctg gagggattat gagaaataaa
    43981 ataattatag gaattacttt ttcacttgta ttactaatgt ctggatgtgc ttcaaaacaa
    44041 accgcagaaa taaacgtatt agcaactact gatttacatg gagttatacc ttatgagtta
    44101 acttcttatg taaaagaaga aagaaaaaaa gataaaaatc taactttagt agatgcagga
    44161 gatttttttg atagtggaga agtgtttggt tctagcatgg atagttattt tagtgctaga
    44221 tataaagatg gtgataataa cactgaaagt tatattgaga cgcctatttc aaaagatatg
    44281 aaagaggtag gttatgatgt tgcagttctt gggaatcatg aatttatatc caacaataaa
    44341 ttttatctag ataatatgat atctgatttt gagaagcaaa aaataaatat tttatcggca
    44401 aatacgtata aaaaaaatgg agacagttat acaaaaccat acataataaa aaatattaat
    44461 acacctgaag gaaacgtaaa actaggaatt ttagggctta ctataaaaga agttggtgag
    44521 aggaaacagt ggaaagatgg aaaacttgtt gactctaagt ctttagaact aaaagaccaa
    44581 gagggttaca atggtgaatt gtatatgaat gatttagtag aagatgctaa aaagtgggtt
    44641 gggataatgg aaaaagagaa gcctgacatt atagttgctg tggcacatac aggtgagaaa
    44701 cctaagaaac ctagaaaccc aggaaataga atacaagact tagctcaaca agttgatgga
    44761 attgatgcta tagttgcagg tcataatcat gttcaaattg agcaacatga ttataaaaat
    44821 aaatcaggag aaaatgttat agttactgag ccaggaaagc atggagaatg tatttctaag
    44881 attaatttta aattagaaaa aaacaatgat aaatggaata tagttgacaa atctagtaaa
    44941 ttaattaaat ttgaaaaaaa tcaagaaagt gataaatttg gagaatttat ttcttcaatt
    45001 aataaagtaa gtaaagataa gaaagaaata agattatcag aagtaaagac tcctgaatgg
    45061 gataaaatat atgtttttaa atctggaaca tctgcagatg atatatataa aacaatagga
    45121 tataaatgga gaaatatatc atctccaaag ggtgatgaca tggtgcagat tgttgtaatg
    45181 aataataata agcctgttag ctatgtatat ggtgaagctg aagttatgcc aattaatata
    45241 aaatgtgatg aatcagagta taaagataat gttgtaacta tttatcctaa taaaaatgat
    45301 aaatttaaaa ttgaaaaagg taaacaagaa tatagtatta atttaaaaca tatacaatag
    45361 aaacttttat cttatttaag tttagattgt acttaaaata aagtgtgtat tattttaaaa
    45421 attgatgata attaaaatca caacattaag gaatagtaca cactttttat gctaaaaaat
    45481 agaatgttaa aaaattaaac ctttaaatta aagtacattg cttatattat ccaatattat
    45541 cttcaaaggt tgtgtaatat ttttatcctt atgtaatatt gctaacattt tattttccat
    45601 atctatccca tctaatttaa tcaatcgcaa ttttttatga aagagtgaat ctaataataa
    45661 attttctggc aaaatggtta tacctaaccc tgcttctgca gctttaataa gtgcaaaaga
    45721 attaacactt tcccaaacag gataagcttt ttggtttgaa agagataata cactgtccaa
    45781 agtatcgcga atggcacttc cttgctcacg taacaataac ggaaacgtgc ataactgtcg
    45841 tagagataag gcttgtttag ataaaggaaa agttggagca catgcaacac ataacttata
    45901 ggaacctaat aaaattgtac ggaatgcccc ctgtggttct ataccttccc aaaagcatat
    45961 atcagcttct ccacttttta aaatatccat agctgaatta gcactttcga cacgtacatt
    46021 cactttaaga gatgggaatg aattttttag tcgacttaaa attggtggaa gtaaaaaaga
    46081 ggcaattgta atgctagaaa caatgtttat aggtgtacat tcctctaaat gactgattct
    46141 tttgtctaaa ttacgacaag cagttaagat actacgtgct tcttctaaaa gagaaatgcc
    46201 acagcgagta agacataccc ctcgtggtag tctgtcaaat aatgctgttt cagcttgttg
    46261 ttcaagttca gctatagcat gagatacagc agattgtgtg atatgtaatt tttttgcagc
    46321 acctgtaaaa gtgcctgttt gttcaattgc ttctaaaatc tctaaatatc gtatgtttat
    46381 cataataaat atcctcacta gacatgaata aaattgatta attccattaa attctatcat
    46441 tttacagatt gcaaagcaac aggtatactg aataatatga agtgaaaaga aggaggaata
    46501 ttttgaatca aagcagaaaa acatattttt ggcttttaat tattaacttg tttattagca
    46561 cattcacttt tggtggaggg tatgtagttg tacctatgat tagacgttat tttgtaaatc
    46621 aaaagcaatt ctttacagaa gatgatttga tgagcatggc agcagttgca caatcaactc
    46681 ctggagctat tgcaattaat ttatctgctt tggcaggtta tcgagtagct ggtactttag
    46741 gggttgtcat tagttgtata gcagctataa tacctccgct cgttattctt ggattagtat
    46801 cagcatttta caccactttt atatctaatg ccattgtaat tgcagtatta aaaggaatgc
    46861 aagctggtgt tgctgcacta attgtggatt tgattattga catgtgctct atgatattaa
    46921 aacaacgttc tctattttta tcagctatga tacctattgc tttctttgca aactttgtga
    46981 tgagtataaa tgtaattttt atattatctg tttgctgttt tgtatgtgta atgcaagttt
    47041 tctacaagaa gagggaaaat aaatgaatac aatttggaat ttatttttta tatttttaaa
    47101 aataggcttg tttagtattg gtggtggtta tgcaatcata cctttaatcc aagagaaagt
    47161 agtaaatcaa actggatgga taagtgagaa aatatttaca gatattataa ctatttcaca
    47221 aatgacacca gggccactgg ctgttaatac ttctactttt gttggacttc aaattggagg
    47281 gttttgggga gcagttgcag ccactttagg ttgtgtatta tgtggtgtag taatatctct
    47341 atttttatat aatttttttc aaaagcatca gaactctact tatatatttg aaatattaaa
    47401 tggtctaaaa tcagcttcat taggtttaat tatctcagct gcggctacaa ttataatcct
    47461 tgcattattt gggacgaata aagtgtactt caattctata tttgagatgc taaactggac
    47521 tgcactaata atcttttttg ttacactact gatagtacgt aagtggaaaa ttaatcctat
    47581 tgtgattata ataataagtg gtatactggg aatatttttt tatttataag tttttgctaa
    47641 gtaaaggata tctatttttt tatatcttaa atccaaatag ccaataaagt aaggctattt
    47701 ggatttttaa taaattctga aaagataatc agaaacccat ataacattta aattatatca
    47761 ctggttttct acaaaccaat cataagcttc ttggcaaaat ttctcactat ctatatagta
    47821 actattatga acattattaa tttcaacaag tttcttttta cattttagtg aattataata
    47881 gctatcaaaa tattgggttt taaaatatct atcatgaagt gttttaaaga caagagtagg
    47941 tatgttgact ccatctttta tcttactatc ttctgcaata aagcattcta acattgtatt
    48001 aattatcttt gtactatttt tccaaatatg aggatttttc ttttcaaata ttttataaaa
    48061 ttcattatca tagacttcat tataaccttt atatttaggt ggttttactg ttatgtgaaa
    48121 attaggaaga aacttaaaga aaaaatataa taatttttat gttctgtttt atatattatt
    48181 catattttat cacagataat atactaaagt taattttttt attgtacaac tattataata
    48241 attcttctat aatataagac attctataat tttatattta agttcatgtg tatttaattg
    48301 tttttatata aaatgtccag taatactatt tggatttatt tttatttcat caggagttcc
    48361 agaagcaaca atttcccctc catttattcc actgtctgga cctatatcga taatccaatc
    48421 agaagcacgt ataacctctg tattgtgttc aataattaaa agtgaatgct gttcatttac
    48481 aagttttcta aaagtaatta acaaattttc tatatcttta aaatgaagtc cagtagtagg
    48541 ctcatccaat atgtacagca ttcgtttttt agtttttgtc cctaattctt ttgctaattt
    48601 tatcctttga gattctcctc cacttaatcc taatgtattt tgtccaagct ttagatatcc
    48661 aagtcccact tcatctaata aggagagttt tctatatata tcagagcaat cgctaaaaaa
    48721 tgtttttgct tctgctactt ccatgtcaag tatatctgca attgtctttc ccttgtattg
    48781 tatagacagt atttcttttt gatatctctt accttgacat tcactacaag ttacccattg
    48841 gtctgccata tattgcagaa taatttttgt tttacctaat ccttgacagt ttgggcattg
    48901 cccctttttg ctattaaagc taaaatagct ttcatccaat aatttttgtt ttgcttgtgg
    48961 agtttcagca aatagagaac gaatttcatc aaaaatattg atatatgtag caggtgtaga
    49021 acggctagat tttccaatag gtgtttggtc cattaagata aaatcatcaa tagcatcaaa
    49081 tccagtaaat tcagtataat ttttatctgg gatagatttt tgtttcaatt tttcttctag
    49141 agcaggaagt aaactgtgaa atacaagaga gctcttacca gaaccactaa cacctgtaat
    49201 agagcacata cagtttaagg gaatttctac atcaatattt tttaagttat ttgcatggca
    49261 tccttttaag cttaaccatt tacttggtat agttttattt tgtgaacctg ttttattgta
    49321 tgtacttaaa tatttacctg ttatagagtt tggatttttt ataatttctt gggttgtacc
    49381 ttctgcaata atgaaccccc cttttgtacc agcacttggg cctacatcaa taatataatc
    49441 agcagacagt attgtatctt tatcgtgttc cacaactata acagtattac ccttatctct
    49501 tagctcttct atcattttga tgattaaatt atggtctctt gggtgtaaac caatagatgg
    49561 ttcatctaaa atgtaggtta agcctactaa ttcacttcct agctgacttg ataatcgtac
    49621 tctctgcagt tctcctccag ataaagttgg agctgttcta tctgttgata tatagctaag
    49681 acctaccttt aatagataac taactcgaat ttttaattct gttaagatat catttaccaa
    49741 agagagctca tttttttgaa gttgatttgg taattcacac aaccaattcc ataactgttc
    49801 tatcgtcatt tttgttagtt cagggaagcg ataacctttg attgtagtga atctagcctc
    49861 aatgcacagc aattcgccac cacatgtatt gcaaggaatt ttgttcatat attgatgcaa
    49921 ggtattattt tcagaactag attctctaaa aagtctttga atgtggttga ttgctcctga
    49981 agcaggtctt ctaatctttg attctcgtcc ctttgattca aagctaaatt catatatctt
    50041 atcgtctgta ccatataaga ttgcatctat aaaatctctt ggtaattcat tccaaggtat
    50101 atctaggtct atatttttat cttttgctat tgcatataat tcacctacca tccaattacc
    50161 atttggcttt ttccccctca attttccaaa atagtaagta gctccatcta atattgaaat
    50221 agttgggtct tttacaatta attgaggatt aacttgatag gtaaaaccta atccattaca
    50281 atcgtgacaa gctccagtat gggagttagc attgaaggtt gaagtattta tcttagaaaa
    50341 aatagtttga caatgtggac aataattttt tgtattattc tttttttcta atggaatttt
    50401 gcaatatgga cagtaacttt ttccgattga tacaaataac attcttaaat aatcccaaat
    50461 gcttgtaaga gtaccaacag tagagcgagg attttggctt ccttttttct gttcgatagc
    50521 tatagtaggg gttaatccct gaagtaaatc aaattccggt ttttgaagct gttctgaaag
    50581 ttttgctcca ttacttagat tttcaaaata acgtcttttt ccttcttcat aaatcgtatc
    50641 gaaagctaaa gaagattttc cactaccact tacacctgta ataacagtta tttgattttt
    50701 tggaattgta acctcaacat cctttaaatt gttttgcctt cctcctttta aatagataga
    50761 gcttttatta tgacaaagtg aatttttaat tgatttattt attgattttg taaatttgaa
    50821 tttcttttct agttcaagag gattgcctaa ttcttttatt tccgaaatac ctaatatttt
    50881 taactgagaa aagattgatt tcaaataatc ttcaggcaat ttttctatta acaaattaag
    50941 gtcttctatt tttatatttc cgcttgataa tatctctgcc atttcatcta ataaatcttt
    51001 ttctgctctt gttaattgat tgtatttttt ggaacttaat tctgtccata aatcccatgg
    51061 aagcaattct aaaccaatca tattattaaa gtcatgtaga agattacctt ttacagaatg
    51121 ccaacctttc caatttttat tatatccaaa gtcatctgga tgagcatgtc cttgccgaca
    51181 tcttatccag gcttctgaac cagttaaaaa accatctgtt tttccgacat catgagtgtc
    51241 aaaattaatt tgaaaataat ttttttgtat gtcatctatt tgtgcatcta ttcttatcca
    51301 tctctttgtt agagtatcat agtattctac aagccagtgg tcttcataag taatctcact
    51361 ttcaaaataa ttagcaaaac ctgctctcat tctagcctca aaacctcgat atcttaggag
    51421 cgatacaaga agtaaagaat aatctctgca cattccaaca agcctttgtt ttgggtttct
    51481 tggaatagtt agtgggttag aatttatttc aaatattctt tttaacattt gaggaattgt
    51541 acgaagcaat tcctcatcag attgttgttt attaaaggat ataccatata attttccttg
    51601 gtctccatga attactaggc tttggaccac ttttaataac tcaattggag tctttggtaa
    51661 atcttggtat ttattttcaa attttttagg atttgtgatg atgctttgat ttttatagtt
    51721 atttattttc atttatattt cacctctcta aatggatgat ataccctgac atggtgtcat
    51781 atgcaaggac aatctagatt ttttggccaa aatttaaaaa taaataaaaa atgatacagt
    51841 gataaattgt aatacaaata tagtttcaaa ttgcatataa tataattatt taataaaacc
    51901 attatctatg gaatgttaat gaaatgttaa gatggcattc ttgaatatta agaaatagaa
    51961 tactataata tagtgtgaag gattcttagt aaaaaaattt ataagtgtta atatacatta
    52021 aaaaataggt ttataatttg gaggaaaaaa atgaaattat caaggtataa gaaaaatagt
    52081 ttagttctat ctataatttt atgttcactt attatttcaa tccttgtaat tactgttttt
    52141 aataccgtaa aactacacaa tatatctaat aaacaatcta aaaactattt aaatgatgta
    52201 tctacacaga ttgtaatgaa tgttgattct aaaatcaaat ttattttatc cgacttaaga
    52261 ataatggcag attttattaa gcaatatgaa ggtgatagtc gatatgagta tttatctaaa
    52321 agaaagacta gttataagta ttatgatgtt ggaataatag atttagaagg taaagctgag
    52381 tttttaagtg gaaaaaagtt cgacttaaag aatactgctt cctataaaaa aggtattgaa
    52441 ggtaaagaat actcagaagt aatagagtca atgggttttg ttctttatag tgtacctata
    52501 tttaatgata atcatgaagt atctagtatt ttaataggtg tatccaataa agaaagtatg
    52561 aatgagattc ttaatataga taactttaat ggagaaggaa ctattgaaat tattaatagt
    52621 aagggaaaac ctcttttcat aggaaaaaat actgaattaa taaaagacct tagccataaa
    52681 tataaggatt ctgcagatca accttgggca caaaagatgc ttaatgattt taaaaatgat
    52741 aaatcaggga atattacaat aacctcatca aaaggagtac aatgcttatt aacttatcat
    52801 ccaattacaa taggtttaaa tgattggcac tttcttctca tagtacctga agatgctgta
    52861 cttggtgaac ttaataagtt aaattctttt acaataacaa tgacatttat aattacatgt
    52921 attattggaa ttataacatt aattttatat attataagaa gaaaatatgt aaatcaaata
    52981 gaaaatattg catatttaga tagtataaca aatggcataa attcaactaa gtttagtatg
    53041 ctagtcaaac ctttaatttc agaatcacct gatagtactt atatgatgat agcaatgaat
    53101 ataaaagatt ttaagctaat aaatgattgt ttcggtagtg aaaagggaaa tatgacacta
    53161 aaacatcttt acaatgtttt gtataaaaac attgatgaaa atgaagaatt tgtgtgccgt
    53221 catgatgcag accttttcta tttgcttatt aagaatagac cagtgttaga agccctggag
    53281 ttattatata aaatagaaga tgacacaaat tattttaata aaaataggga aaatccatac
    53341 tttttaagac tatccgtagg tatttacaca attgaaaatc ataatgaaga tttaattaca
    53401 atacaagacc atgcaaatac agcaagaaaa agctttaata aaactcatca aagtgatttt
    53461 tctttttata gtgatataga aagaaaacga ttaatatctg aaaaggaaat ttcaaattta
    53521 atggaaaaag cccttgaaaa taaagaattt tttatgtgct tacaacctaa aattgatata
    53581 aaaagtggaa aaattagtgg agcagagtct cttgtgcgtt ggaaaaattc agaaaaaggc
    53641 ataatttatc caagtgattt tattcctctt ttcgaaaaaa gtggatttat atgtaagtta
    53701 gatttatata tactagaaga aacatgcaaa ttgatttcta agtggataaa agaaggtaaa
    53761 gaagtgttga gaatttctgt taatgtatca cgtcaacatc tgaatgataa attgttttta
    53821 gaaaaatata agcatatatg caataaatac aatgtaccaa catgtctgat agatttagaa
    53881 cttactgaat ctattttctt agaaaatcca gaagctatag atataataga ggatattcat
    53941 tctaatggat ttaaatgttc tatagacgat tttggatttg ggtactcatc attagggata
    54001 ttaaaggatt ttaaagttga tataattaag ttagaccgtt cattctttgt tagcaaaaat
    54061 aatatagacc gtggtaaggt agttattaag tctattattg aacttagcaa aaggctaggt
    54121 atgaaagtaa ctgctgaagg aattgaagaa ttagaacaag ttgagttcct aaaaaatgtg
    54181 ggatgtgatt atattcaagg ttatgttttt tcaaaaccat tattaatttc tgactttgaa
    54241 aattttgcat atgaaaataa taaaattaaa aatatccatt attaaatgta caagataaaa
    54301 aatttaggca agttatataa ttaaaaatat aacttgcctt ttttatttat atatttaata
    54361 aaaatatatt tgcagatttt gtaaaaataa ttttcaaatg ttgtaagttg tggctaaagc
    54421 tttattgtat tattctgaat atagaaagat agttactgtc ttagataaaa actgaaacat
    54481 acataataat ataaaatttg ctatattaat aactctaatt attttggaag gagggaaaat
    54541 atgataagtg ggagaatgtt actcatcatg aattttctaa aaggaaaaaa taagacaagt
    54601 tacaaggata ttagcaaaca acttagtata gaagaaagaa aagttagata tgatataaat
    54661 aatttaaata ttgttttgcg ttcattaaac aagtcagtaa tacaaaagat gaacaaaggt
    54721 gtgttaatta ttcctgatga cttccaagta gtatgtataa ataataacga atatgtattt
    54781 tccttaactg agcgagtatc tattatgaaa attatatcaa tgtttaaaat agataatcta
    54841 aacttagaaa aattaagtaa agaatttcag gtttctagaa gttcaattaa aaatgacctt
    54901 aatgttttgt caagtgaatt agaaagaaac caaataacta ttacttatga taaatctttt
    54961 aaaataagtg gagaagaaga cattatatat aagcaaagat tgaacatatt aaaatcgtat
    55021 tcttatcttt ttggtaagga aaaatctgat ttaagtgtat ttgagaagta tttagtgaat
    55081 gtaattgaaa aaatattcaa agggatttat ttgattgata tatataattg gtctatgaat
    55141 ttattattgc aaatgggatg gactttaaat gatgaatctt ttacatggta tgtgtcaaac
    55201 attttccttt ttacatggta tatacattca gatgaaaaac atcctttaga atctgcttca
    55261 ttaagtgagc cgtgttttga aaataagttt gaccaagaat ttgaaacaat tattcaaaaa
    55321 aagttgacta aggaacaaat ttttctgtta aagagttttg tattttttac aaataaatat
    55381 gcaagtttaa acgaggatat ggatttgatt agtacagaaa ttatagttca agacctaatt
    55441 tacaatatgt cagaaatatt agagattagc tttaaagaag atatgattct ttataaagga
    55501 ttactcaatc atattgcccc attgatagag agaatcaagc agaatataca gatttatgag
    55561 gaattacttc atgtaatacc agataaatat caatatgtac ttgaagctac taaggtttct
    55621 attcaaaaaa acagagtttt aagtcaaata aagaatgaaa atgaaacaat acttttggca
    55681 atacatttct taggaagtat acatagaaat gagaggaata actacaaaaa tatattgtta
    55741 gtttgtggat ttggatatgg tgtaattgct atgttaaagg atagtttagt aaatgattac
    55801 cagataaata tagtagagag tattccatca tataagttac aagattataa agactgggaa
    55861 agtattgact tcattataac aacatcaaag atagtaatag acttgcctaa aacaattatt
    55921 gagataaatc catttttaca agaagaggat tatttgaagt ttgaagaaaa agggataaaa
    55981 agaaagaatg tcttaactaa ttatatgtca ataaaaaaaa ggttggactt tttagaagaa
    56041 gatgcccaaa aaagagtatt aagtattata tgtcaagaac ttggatacag tgatgagaga
    56101 atattattta gacaacttaa tttaagtgat ttaataggga ttgataccat aaggataatt
    56161 gatggagata tgaaatggga agatgctgta aaatttagtt caaacatact tgctaattgt
    56221 gattttgtat cagcacaata tgctgagaat attatagata ttttaaaaaa tgtgggtttt
    56281 tatgctgtaa aagataacga atttgcttta ctacatggca atgatagttc attagtcaaa
    56341 gtaagttcga taagtttatt aatatgtaaa gaagcagtta gttttggaga taaaaaggtt
    56401 aaaatcatat tttgcctagc aagcagagat aaaaaagagc aaattcctgc aataattaat
    56461 ctaactaaaa tggtttataa gactaatttt attgctatgt tagaaagtgc aaagacaaaa
    56521 gaagaagcag aagttttaat tcataaatat gagaaggagg tcactgtatg aataaattag
    56581 ttaatgtaaa atgttcattt aaaatacatg ttaattcaaa agaagaagcc attatatcgt
    56641 tagttgatgt agtgtcaaaa gaaggatatt taatagataa aaatcaattt ttaaaagatg
    56701 ttttaaagag agaagaaaca ttgtcgactt atattggaca tggtataggt cttcctcata
    56761 gtcaaagtgt aggtgttaaa aactcttgta ttacaatagg aaagcttgat actcctattg
    56821 aatggacaga agaaggagaa aaagtggatt taatattttt gatatcagta acaaaagaca
    56881 atgaaaataa tcttcattta aagattttat caaaattagc acgtttattg atgcatgaaa
    56941 gttttagaaa tcaaattaga tgttcagatg aacaaactgt ttataatctt ataaaagaaa
    57001 aaatagagga ggaagattaa aatgagaatt ttaaagtttt tgcaaaaaca tcttatgaca
    57061 gcaacatctt atatgattcc atttgtggtt gcaggaggaa tattatttgc tttatcagta
    57121 actctaagtg gacaagctgc tgttcctgaa acaggctggt tggctaaact gaatcaaatt
    57181 ggagctgctg gcttggcttt attcattcct atattaggtg gatatatagc atttagtatg
    57241 gcagataaac caggattagc tccaggtatg ataggtgcat atttagcaaa agaagtaaat
    57301 gcaggtttta taggtggtat catagcagga tttatagcag gatttgttgt tttacaatta
    57361 aagaaaatta aattagctcc tacaatgaga actttaggtt ctatatttat ttatcctttg
    57421 attggtacat tgattacagg tggtataatt gtatttttaa ttggagaacc tatagcttct
    57481 tttatgacat ggatgacaaa ctggttaaat ggaatgtctg gtgtttctaa aattccttta
    57541 ggtggaatct taggaggaat gatagcctca gatatgggtg gtcctataaa taaggttgct
    57601 gctacttttg cccaaactca agttgacaca cttccatatt taatgggtgg agttggcgtt
    57661 gcaatttgta tacctccaat tggtttagga ttagctacat tattgtttcc aaaaaaattt
    57721 agcaaggaag aaagagattc aggtaaagct tcactattaa tgggatgtgt tggaattaca
    57781 gaaggagcta ttccatttgc aacatcagat ccagttagag taataccttg tattatggct
    57841 gggtcgatta taggaaatat tatggctttt ttattaggat gtttaaatca tgcaccctgg
    57901 ggaggcctga tagtattacc tgtagttgac aataggttgg ggtatattgc atcagtatta
    57961 actggagcag tagttgttgc agtattaatg aaattagtaa aaaaagacgt gaaagaagat
    58021 gaagaaattg aagaagattt agatgaatca attgaattaa tatttgaaga attataaata
    58081 taaatggaag gaatttgtat aaaaaagtaa atataaaact ataaatttaa aggagataag
    58141 aatatgaaaa ttgtagcagt aacatcttgt cctagtggag tagcacatac ttacatgtcg
    58201 gctgaatcac ttgaattatc agccaaaaaa tttggtatag aaataaaggt tgagactcaa
    58261 ggaagctctg gaatagataa tgaattgtca cttaaagata ttgatgaagc aacttgtgta
    58321 atattgacta atgatgttga gattagaaat atggaacgtt ttaaaggaaa gaaggtagta
    58381 agaatgagtg tatctgagat aattaagaaa tctgatgcat taattaagaa aataaaagat
    58441 acttttcaat aaaaattgat ttattttaca tataactcaa agatgttttt aaagaaattt
    58501 ttattaaaag catctttgaa aatatcttaa aaatagaata aaaggagata tagtcatgaa
    58561 aaagttacca ataaagactg tcgtgcaaag attactaaac ttacaagaag aggggaaaag
    58621 tgcaactctt ttaggaattg gtcctatgtc accaaacttg ttacaagcaa gttttgaact
    58681 agcaaaagat gatgattttc ctttaatgtt tatcgcaagt agaaatcaag tagatgcaga
    58741 tgaactaggt ggcggttatg taaatggttg gaatcaggaa acttttacaa aagatattaa
    58801 gaaggttgcc gacaaagttg gatttgatgg tttatattat ttatgtagag accatggtgg
    58861 gccatggcaa agagataaag agagaaatga ccatttgcct gttgatgaag caatggagtt
    58921 aggaaaaaaa tcttatttag cggacattga agcaggtttt gacctattga tgattgaccc
    58981 tacaaaagac ccatttgaaa ttggaaaagt aattccacta gatgtagtac tagaaagaac
    59041 tgtagaatta attgagtatt gtgaaaacga gagaaaaaga cttaatctac cagacatagg
    59101 ttatgaggtt ggtacagagg aaaccaatgg aggtctgact tcaactgaga cgtatgaaac
    59161 atttataact agactaaagg ttgaactcga taatagaggt ttgccaatgc caacatttat
    59221 agttggtcaa actggtactt taactagaaa gacagaacaa gtaggaactt ttaattttag
    59281 aaatgcttat gatttagctc aaatggctaa gaaatatgga gttggtttaa aagagcataa
    59341 tggcgattac ttagatgatg taactttatt agaacatata ccatctcaaa ttattgctac
    59401 aaatgtagct cctcaatatg gtactgaaga aactagggca tatttaaaat tagcagaagt
    59461 tgagtgtaaa ttagaaaaag agggtttagt tgagaaaact tctaatatca gacatgttct
    59521 tcttgttaat gcaattgaat gtggacgttg gagaaaatgg gtagtaggag aacaaaaaaa
    59581 tctaactact gaagagatat ttaaggatga agttttatct aatgaaatac tagatattgc
    59641 aggacattat acatttaata atgatgatgt taaaaaagaa atagaagtgc tttatgataa
    59701 tttaagtaag aataatattg atggtcaaag atttgttgta gaccatatta aacgtccttt
    59761 gcgtgattat gcagaatgct ataacttaaa aggtgttact acgaggattt taaataaata
    59821 ataggactta tagtggtgag tattgttata ctaggtattt atagttataa ttatacttac
    59881 cactattaaa tttaggagga ctaatatttt gattaattta atttttgatg tagatgatac
    59941 tttatataat caattaacgc ctttttacac tgcatataat aaagtgtttt cttcaataaa
    60001 ggatatttct attgaagatt tatatatgag tagtagaaag tatagtgatg aggtatttca
    60061 tatgactgaa aatggagaaa tgccaatcaa agaaatgcat atttatagga taatgaaagc
    60121 ttttgaggag ttgggaaatt ctattacaga aaaagatgca caaagttttc aagatgagta
    60181 tatatatcaa caatcacaaa ttacactaat accagaagtt gagaggattt taaatttttc
    60241 taaagaaaga aatattaatc taggaattat aactaatggc ccatcaaacc atcaaagaat
    60301 gaagttaaag cagttaaata ttgaaaactg ggttgataaa agtaatattt ttatttctag
    60361 tgaggttgga ttttctaagc cagatactaa tatttttaga gtagctgaga atgttatgaa
    60421 tttagataga gaaaatacat attatgtggg tgattcttat agaaatgatg tattaggtgc
    60481 taaaaaagct ggttggaaga gtatatggtt gaaccataga ggatatgagg tagaagaatt
    60541 gttttataaa cctgattttg taattttgga acataaggat ttgatatctt tatttataaa
    60601 aatatgtagt tataaaaata tgtagttata aaaatat
//
LOCUS       DAEQAF010000010        58469 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.010, whole genome shotgun sequence.
ACCESSION   DAEQAF010000010 DAEQAF010000000
VERSION     DAEQAF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58469
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.010"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            92..442
                     /locus_tag="KRN00_000778"
     CDS             92..442
                     /locus_tag="KRN00_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBH1826660.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            461..2104
                     /locus_tag="KRN00_000779"
     CDS             461..2104
                     /locus_tag="KRN00_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBH1826661.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIETKNVDLDTNI
                     STSMDFAKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            2185..4242
                     /gene="recG"
                     /locus_tag="KRN00_000780"
     CDS             2185..4242
                     /gene="recG"
                     /locus_tag="KRN00_000780"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBH1826662.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYSVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            4301..4855
                     /gene="rsmD"
                     /locus_tag="KRN00_000781"
     CDS             4301..4855
                     /gene="rsmD"
                     /locus_tag="KRN00_000781"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBH1826663.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            4857..5354
                     /gene="coaD"
                     /locus_tag="KRN00_000782"
     CDS             4857..5354
                     /gene="coaD"
                     /locus_tag="KRN00_000782"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBH1826664.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            5358..5882
                     /locus_tag="KRN00_000783"
     CDS             5358..5882
                     /locus_tag="KRN00_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826665.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            6227..8146
                     /locus_tag="KRN00_000784"
     CDS             6227..8146
                     /locus_tag="KRN00_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1826666.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINEQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            8159..8446
                     /locus_tag="KRN00_000785"
     CDS             8159..8446
                     /locus_tag="KRN00_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1826667.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            8579..9838
                     /locus_tag="KRN00_000786"
     CDS             8579..9838
                     /locus_tag="KRN00_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBH1826668.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            9841..10581
                     /locus_tag="KRN00_000787"
     CDS             9841..10581
                     /locus_tag="KRN00_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1826669.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTVLADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            10922..12214
                     /locus_tag="KRN00_000788"
     CDS             10922..12214
                     /locus_tag="KRN00_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1826670.1"
                     /translation="MEGIKVGMLKKLCSLTMVAIMTTTLITGCSSGNGKDSKKDGEKE
                     KLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISAGEGPDV
                     GYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAANPGVLY
                     YNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFGNLNWNW
                     YPYLWQAGGDIFNDDLKSVKFNDKSGLEAANFLKELQAYVPEDSLSKDSNEMIESVFG
                     PGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSSAKNKEL
                     AYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPLVVGPHG
                     VEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            12312..13229
                     /locus_tag="KRN00_000789"
     CDS             12312..13229
                     /locus_tag="KRN00_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH1826671.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            13245..14054
                     /locus_tag="KRN00_000790"
     CDS             13245..14054
                     /locus_tag="KRN00_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH1826672.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            14112..15860
                     /locus_tag="KRN00_000791"
     CDS             14112..15860
                     /locus_tag="KRN00_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBH1826673.1"
                     /translation="MEISYVLKDCTFKHNKYSVVEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDMLVEQYLPQTFWVEGQVPEDFEENNFNIGIDIFKSFGYEDEEKACTIDVP
                     VEVKNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIIDNYLKELASLGEKV
                     ATIIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYISIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVSTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            16121..17143
                     /locus_tag="KRN00_000792"
     CDS             16121..17143
                     /locus_tag="KRN00_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBH1826674.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGVTKEAPETSRRAWVKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDREILS
                     ALIEKR"
     gene            17148..19454
                     /locus_tag="KRN00_000793"
     CDS             17148..19454
                     /locus_tag="KRN00_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1826675.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSERRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYVLS
                     SLSLKIFSQNIRNVRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSITYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFHMDIKNIGKLRIVNFNYQYVLLNF
                     ENKNIYPKEIALEISEGIVLECDLCEGKIDERGILYRVNNIDSIMQNLFLRDEMMDWI
                     LQNKKILDSKPNEKKEKSIDEFEPMEYI"
     gene            19426..20541
                     /locus_tag="KRN00_000794"
     CDS             19426..20541
                     /locus_tag="KRN00_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826676.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSAKYFILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVKIETNSSKSDKKRYLYIYQNMKENWSMYNNF
                     YIEIQNKNKSSQKINLSIQSKNMLEFRLKEGSEVFLEDKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEKSNVVLDSSMLSNIVSWGITFIPSDEEHNNIIIKKISLLSEEKL
                     SFLHNIKITGNEEVQIPVLGQGISQYEVLGLESDSKIKYSLIGKQDNLSISQKGKLTL
                     NNKSKPGQIILQVDVDDKFKIGKKITLTESWSINKKDKDGVPYTLVSPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            20559..21977
                     /locus_tag="KRN00_000795"
     CDS             20559..21977
                     /locus_tag="KRN00_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBH1826677.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCVYNIGVLFIFKYLAFAL
                     RNISELINTELTIPNIILPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTMQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMLGG
                     NGVIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQVKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            21993..23201
                     /locus_tag="KRN00_000796"
     CDS             21993..23201
                     /locus_tag="KRN00_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826678.1"
                     /translation="MNRFFKVRLITAIMFLVVLFAFSIFNICYSGKDMIQEIKNSVAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSSVKDTSGKMHYTY
                     FAKAPNPIGVISDRVRKFSEEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELIEQLNKK
                     YNINLDENHYYRDKENYNSIVYPKSFLGSMGRKSGILYGGIDDFALIYPKFKTNYTYY
                     TDSKFQKFELKGRFEESLILSYPFNADLNLMDGQSDKYSTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISIYPQN
                     LTKEFFPFCE"
     gene            complement(23275..24663)
                     /locus_tag="KRN00_000797"
     CDS             complement(23275..24663)
                     /locus_tag="KRN00_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBH1826679.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVTWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLRK
                     IDKEVFSKKNIS"
     gene            25004..26338
                     /locus_tag="KRN00_000798"
     CDS             25004..26338
                     /locus_tag="KRN00_000798"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBH1826680.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPPIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNVSK"
     gene            complement(26467..27384)
                     /locus_tag="KRN00_000799"
     CDS             complement(26467..27384)
                     /locus_tag="KRN00_000799"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBH1826681.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            27592..28476
                     /locus_tag="KRN00_000800"
     CDS             27592..28476
                     /locus_tag="KRN00_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBH1826682.1"
                     /translation="MKVLKKITILSLITLTLVGCSNGEDKKVVEGSKKIQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            28689..30530
                     /locus_tag="KRN00_000801"
     CDS             28689..30530
                     /locus_tag="KRN00_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HBH1826683.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVED
                     IKIENKSARLIGKEEALKYKLDSAVSKKVDKIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            30835..31542
                     /locus_tag="KRN00_000802"
     CDS             30835..31542
                     /locus_tag="KRN00_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826684.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            31536..32846
                     /locus_tag="KRN00_000803"
     CDS             31536..32846
                     /locus_tag="KRN00_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1826685.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTIVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKSEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            32963..33646
                     /locus_tag="KRN00_000804"
     CDS             32963..33646
                     /locus_tag="KRN00_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826686.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            33639..36026
                     /locus_tag="KRN00_000805"
     CDS             33639..36026
                     /locus_tag="KRN00_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1826687.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKSDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKNNLNILQMNNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            36306..37448
                     /locus_tag="KRN00_000806"
     CDS             36306..37448
                     /locus_tag="KRN00_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1826688.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKEYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKVPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            37467..37991
                     /locus_tag="KRN00_000807"
     CDS             37467..37991
                     /locus_tag="KRN00_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1826689.1"
                     /translation="MEVTVKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIVFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKKCIK"
     gene            38091..38909
                     /locus_tag="KRN00_000808"
     CDS             38091..38909
                     /locus_tag="KRN00_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1826690.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDFMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGVSFYPFGLYPFLKI
                     PISEFNRQIVDLEAVSKLFAKKLEESLSPTQSVEKVVLCLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            38987..39298
                     /locus_tag="KRN00_000809"
     CDS             38987..39298
                     /locus_tag="KRN00_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBH1826691.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(39475..40158)
                     /locus_tag="KRN00_000810"
     CDS             complement(39475..40158)
                     /locus_tag="KRN00_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826692.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIYNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(40251..40892)
                     /locus_tag="KRN00_000811"
     CDS             complement(40251..40892)
                     /locus_tag="KRN00_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1826693.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYDVKNDEGKTALEKLQYRLLHAYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMQVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(41066..43069)
                     /locus_tag="KRN00_000812"
     CDS             complement(41066..43069)
                     /locus_tag="KRN00_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBH1826694.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAMSLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLSFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFSSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(43222..43860)
                     /gene="recX"
                     /locus_tag="KRN00_000813"
     CDS             complement(43222..43860)
                     /gene="recX"
                     /locus_tag="KRN00_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBH1826695.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGSE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            44136..44825
                     /locus_tag="KRN00_000814"
     CDS             44136..44825
                     /locus_tag="KRN00_000814"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBH1826696.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            44826..45398
                     /gene="yqeK"
                     /locus_tag="KRN00_000815"
     CDS             44826..45398
                     /gene="yqeK"
                     /locus_tag="KRN00_000815"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBH1826697.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            45515..45865
                     /gene="rsfS"
                     /locus_tag="KRN00_000816"
     CDS             45515..45865
                     /gene="rsfS"
                     /locus_tag="KRN00_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBH1826698.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            46219..48639
                     /locus_tag="KRN00_000817"
     CDS             46219..48639
                     /locus_tag="KRN00_000817"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBH1826699.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            49493..50161
                     /locus_tag="KRN00_000818"
     CDS             49493..50161
                     /locus_tag="KRN00_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1826700.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKISILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            complement(50479..50751)
                     /locus_tag="KRN00_000819"
     CDS             complement(50479..50751)
                     /locus_tag="KRN00_000819"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1826701.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(50975..51396)
                     /locus_tag="KRN00_000820"
                     /pseudo
     CDS             complement(50975..51396)
                     /locus_tag="KRN00_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(51415..51588)
                     /locus_tag="KRN00_000821"
                     /pseudo
     CDS             complement(51415..51588)
                     /locus_tag="KRN00_000821"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            51802..53172
                     /locus_tag="KRN00_000822"
     CDS             51802..53172
                     /locus_tag="KRN00_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBH1826702.1"
                     /translation="MKLKKLLSLGLVSMFVAGFPISANALDKIDKIQGADKYETAGII
                     ADKQSYTTAILINADSTMADGLSASGLAGATNAPILLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETFLTDKGIETRRLQGNDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGIESYAIGGTSSMSDSLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVGSPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSNHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            53531..53689
                     /locus_tag="KRN00_000823"
     CDS             53531..53689
                     /locus_tag="KRN00_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826703.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   53975..54466
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=53975..54003
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(54608..54705)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            54931..55314
                     /locus_tag="KRN00_000824"
                     /pseudo
     CDS             54931..55314
                     /locus_tag="KRN00_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(55492..56487)
                     /locus_tag="KRN00_000825"
     CDS             complement(55492..56487)
                     /locus_tag="KRN00_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBH1826704.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(56608..58236)
                     /gene="aspD"
                     /locus_tag="KRN00_000826"
     CDS             complement(56608..58236)
                     /gene="aspD"
                     /locus_tag="KRN00_000826"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBH1826705.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEDLFKFISKNASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWKKIKK"
BASE COUNT        22560 a         6638 c         9875 g        19396 t
ORIGIN      
        1 atgattataa ttttatataa taaataagta aaaatagtaa aaaataaatt aagaaatgtt
       61 tttaataaaa ataagcttaa gggggtcaac catgagtgca aaggtaacga atcaatatgg
      121 aaatatagaa atagataatc aagtaatagc tcaagtcgta tatagagctg caatggaaag
      181 ttatggctta gtaggtttag catataagtc taaaggaata gtagagctat taaaaggcga
      241 gaacgcaact aaaggtgtaa gagttgagga agtagaagaa gatgccatag caatcgaact
      301 ttatgttata atacaatatg gtacaaatat atctactgtt gccaataata taatagatag
      361 agtaaaatat gtagttgaaa aaatgactgg cgtaagagtt actagaattg atattaatgt
      421 acaaggaata agagttaagt aatttcatag gaggaaacaa atgattcaat atatagatgg
      481 taaaaggtta agggagatgt ttatttcagg tgcaaacaat ctccaaaaca ataaagagtt
      541 agttgacaag ttaaatgtat tccctgtacc agatggagat acaggaacta atatgtcatt
      601 aacaatatct tatgccttaa aagaattagc aaaagttgaa aatgataata tatcagatat
      661 cggaaaagca ttatctaaag gttctttaat gggagctaga ggaaactcag gagttatact
      721 ttcacaaata atcagaggta tagctaaatc tatagaagga aaaagtaaat tatcaacaga
      781 agatttagca aaagctttta aaaatggttc agacacagca tataaagctg taataaaacc
      841 aattgaagga actatactta ctgtagttag agaaagtgga gagtttgcaa taaaaactgc
      901 gaaaaaagag aaagatgtag taaagttttt aagtatgctt gtgaaggaat caaattcttc
      961 attagaaaga actccagacc ttctaaagaa tctaaaagaa gctggtgtgg ttgactctgg
     1021 tggaaagggt cttgtactta tatatgaagg aatgttagct tctataaaag gcgataacat
     1081 agaaacaaaa aatgttgacc tagatactaa tatttcaaca agtatggatt ttgcaaagag
     1141 tactactagc acagatgata taaaatattg ctattgtaca gaatttattt tagaaagttc
     1201 taaggtagaa gatactaaaa taagagacat aatgatggct tatggtgata gcctagcagt
     1261 agttggagat gatggagtca taaaggtaca tgtacacact aatgacccag gaaatgtact
     1321 tcaagaagct ctaaagtacg gtcaattatt aactataaaa atagaaaata tgaagttaca
     1381 acatgaaaat acattactgg atgtagaaga aaagaaagaa aatgatagtg aacctttaga
     1441 agaagaaaaa gagtttgggt ttatagctac ttctatgggt gaaggtttgg caaatatatt
     1501 taaagatttc ggagttgacc atataataga aggtggtcaa actatgaatc caagtactga
     1561 agattttatg aatgctataa agcatataaa tgctaaaaat atatttattt tcccaaataa
     1621 cagcaatata ataatggctg ctaatcaggc aaaagaattg agtgataaaa atataatagt
     1681 tatacctaca aaaaatacgc ctcaaggatt tgctgcatta gtaactttta atggagaatt
     1741 aagcgaagat gaaaataaag aagctatgat gaatgcttta aactcagtta aatcaggtca
     1801 agtaactttt gctgttaggg atacagtgat gaacgaaatt gatgttaaag aaggtaatat
     1861 aattggaatt gcagaaggga atttattatc agcaggagat tatgtggatg aagtaacatc
     1921 aaaccttatt gaaaagttgg ttgatgaaga tactgctata ataacattat tctttggtga
     1981 agatgttaca gaatctcaag caaatgaact acgtacttct ttagaagaaa agtttgaaga
     2041 tgtagatgta gagttatatt atggaggaca acctctttat tattacttaa tttcagttga
     2101 ataatgatta taagaacctg tatgaccaag tagcttttat aaaattggtt gtacaggatt
     2161 tttgtgtagt aggtgatata tttgttggat ttatataaag atgttcaata tgttaaggga
     2221 ataggaccta aaaaagcaga taaattaaat aaactgggta tatttacact aaaagaccta
     2281 ttgtattatt ttccaagaca atttgaagat agaaataatc taaagaaaat agcacaatta
     2341 gaagatggtg agaaagttac gataaaagca gtaatatcaa gtataaatac atttagccca
     2401 aaagaaggta tgactttaac aaagattgat gtaaaagatg agacaggctc ggctaaatta
     2461 gtgtttttta ataagagtta tataaaaaat acttttcgtc caggagattc aatattagtt
     2521 tttgggaagg ttaagaaaaa atttaataac ttagaactta catcatgtga attagaatat
     2581 cttactaatt cacctaagaa tacatgtaga tttatgcctg tgtaccagct tacatacagt
     2641 gttacaaata aagaaattat gagtataatt agaacagtac ttgaagataa agaattaatt
     2701 atacaagaat atatgccaca aagaattata gaaaaatata ggctatgtag tatagatttt
     2761 gcagttagaa acatacattc accaagtagt aaggaatcat taaaaatagc tttatataga
     2821 attgtatttg aagaattact tatactacaa ctagggttgt ttgtatttaa aagtggcaga
     2881 aataaagaag atggaataaa gtttgaaaca agtaaagact taaaaaaaat aataagtgct
     2941 ttaccattta aactgactaa agctcaaaac agggcattag atgaaattat acaagatatg
     3001 aatttagaga aaataatgaa tagattggta caaggtgatg tagggagtgg taaaacagta
     3061 gtagctctct tagcacttgc aaattgtgtt ttaaatggtt atcagggcgc tttgatggca
     3121 cctacagaga tattagcagg gcaacattat atttcactta cggagtctct aaaagatttt
     3181 ggaataaatg taggtctatt aataggtagt cttacaaaaa aacaaaagga tacagtattg
     3241 gaacaaataa agaataatga gattgatata ttaataggta cacatgcact aattgaagat
     3301 aaggttgaat ttaataatat tggtttagtt ataacagatg aacagcatag atttggtgtt
     3361 atgcaaagga gcaaactttc attgaaagga gcaaatcctg atatattagt aatgacagca
     3421 acaccaatac caagaacttt agcacttata ctctatggag atttagatat ttctattata
     3481 gatgaacttc ctccaggaag acagccaata gaaacaattg ctattgaaaa aagtaagcga
     3541 gatagagcat ataataatct tgtaagaaga gaagttgaat caggaagaca agtgtacatt
     3601 gtatgtccct tggtagaaga aagtgaagcc atagaagcca aatcagcagt tgaacttgtt
     3661 gaggagttaa gagcggaata ttttcacgac ttaaggcttg ggttgcttca tggtaaaatg
     3721 aagtcaagtg aaaaagatga agtaatgaga ctttttaaaa ataaagaaat agatatttta
     3781 gtttcaacaa cagtaataga agttggtgtc aatgtgccaa atgcaacatt gatgataata
     3841 gaaaatgcag aaagatttgg acttgcacaa ttacatcagc ttagagggcg agttggaaga
     3901 ggtagtcata aatcgtattg tgtactaatt tatgattcta aaacagatgt atgtagacaa
     3961 agaatggcta taatggaaga gaccaatgat ggttttaaga tttcagagaa ggatttagaa
     4021 ataagaggac ctggggaatt ttttgggaca aggcagcatg gtcttccaga acttaaggta
     4081 gcaaacttat ttaaacatat aaaaatactg aagttagcac agcaagaagc tcgatatata
     4141 ttgggtgaag ataataatct acaattaaaa gaaaacatgg cactcaaaaa agaaattata
     4201 gataaattta aagatacatt gaaagaaatt tcattaaatt aattttaaat tgtgttaaaa
     4261 tattactaat gtaataatgt gctgaaggga gattgtcata ttgagagtaa tttcaggaaa
     4321 agcgagagga ttaaaactaa atactccaaa aaatgaagat gtaaggccaa ctacagatag
     4381 agtaaaagag tctctattta atatgataaa ttcatatata atggaaagtg aagttctgga
     4441 tttatttgct gggactggtt ctttaggaat agagtgttta tctaggggtg ccaagtcatg
     4501 tacttttgta gatatcagta aggaaagcat agatattgtt aagtccaata taaaaaaggc
     4561 aagagttgaa agtgaaagta ttattttaaa ccttgatttt aagactgcaa tagataaact
     4621 taaattacaa aatagtaaat ttgacataat ttttatggac cctccgtatt ataaaaatat
     4681 gtttatagaa gctattgaaa aaattgataa ttctaatcta ttgaacgaag atggaataat
     4741 agttgtagaa catgatacga atgatttatt tccagataag atatgtaaat tggagaaaac
     4801 tagagataag aaatatggaa atactacatt aactttttat aagatggagg cataatatgg
     4861 aaaataaacc tagaaaagct atatttgcag gaagttttga cccaattact aatggacatt
     4921 tagatattat ttgcagggct tcgaagttat ttgacgaatt acaaatagga gtattaaata
     4981 atcctaataa aaagggtcta tttagctttg atgaaagagt aaaacttata gaaaaaagta
     5041 caagccattt aaataatata aaagttgtga cttttgatgg tttattaata aattactgtc
     5101 aggaaaatgg gattggagca ttagttagag gtgtgagaag tggtgctgat gttgattatg
     5161 aacttcagat ggcgcatatg aatagagagc ttaatccaga tatagagact ataattttac
     5221 caagttgtac aaaatattca tttataagtt catctttaat aaaagaggtt ttgctctttg
     5281 atgctgatat aaaaaatttg gttccaaaga ttgttttgga agaattaaag aaaaaaacta
     5341 gtgggggtaa ttgatatatg aagatagatt tagaaatgat tgaactattt gagcagttag
     5401 aggagatatt tagaagcgct tctacaatcc ctttctcaca taaatgcaca gtggataaag
     5461 atgaggtttt agcaataatt aatgatataa gaactttaat accagaagaa gtaacacagg
     5521 cagtatggat taataaagaa agaaataaaa taataagtca agctaagcaa gatgctacaa
     5581 atatagttga acaagcgaaa aaagaagctg agagaataca acaagaatat caagataata
     5641 tagaggaatt aaagaaaaat tctgaagatg tagtaaaggc atatgtagaa tccagcgaac
     5701 ctgttgttca agcagaccaa agagcaaaag atatagttga tagagctgag agaatagcca
     5761 atgagataag aattgggtca attgaatatg cagaggatgt gctttctagt gttgagtata
     5821 atttaagaga aatattagaa gaagtaaaaa gagataaagc tgaacttaga cctaaaaaat
     5881 aaattttaaa taaataaaaa tggagctatc acacaaaaaa ttccaattta tgtgtgatag
     5941 ctctctttta atatagcaat tttttgttat ataattgtgc tttttagatt acttatatct
     6001 tattttgata ttataatgta gtttaatctt ttatttgttg gaaatcaact tatttatttg
     6061 tataaataat ataggttatt ttcaaatttt tttaataatt ttaccactgt cttcttttag
     6121 attagagtta gactgtgcaa aattataaaa taatactaaa tcatgtgcaa ttatttggta
     6181 tggcactaca tgtagaaaat atagataata aaattaagga ggtagtatga aggaaagggc
     6241 taaaaaaata ttagatttta ttattaaaaa taacaatgta acatcacaag aactacaaga
     6301 aaagtttaat gtttcaaaga gaactattta ttacgatatt ctagctataa atgaacaact
     6361 aggaaaaagt ggtaatataa aaaatgtaaa acacaaattt atatttgaag gtaatttatg
     6421 tgatgcaagg aaaataattt caactgaaga agataaattt ttagatagtg attacagaaa
     6481 aacttttata ttaaacaaga tattacttgg cgaaaaaata tcaatagaaa aactaacaaa
     6541 tgaaatgtta ctttcaaaaa acacagtagt acaaacaata actgatgtaa aaaaatacct
     6601 tcaaacaatg gggttaagat tagagtataa gggaaagtac aaaattatag gtgatgaata
     6661 cgttattaga gagctgtttc tgataattgt tcaagaaaat gtactggaaa ttaattctat
     6721 aagtgaggaa gtaagtagtt tcgatacaaa aggacatata aaacttactg attattcttt
     6781 attaaatcta actaagtttg tggaatttct aaataaaagg ataagagatg ggaaaacatt
     6841 atactcatat aaatatctaa atgaagctaa aaaaattagt tactttagta attgtaaaga
     6901 acttttatgt gaagaagcta atgaaaatga acaagcctat atatgcactt acataagttc
     6961 acttcccagc ttaaatagtg aagttaagga agatgttgtt gaagaatatg tagataaact
     7021 tatagataag tttgaagtaa atacagcaat aaaattagaa agtaagcatg agtttaagaa
     7081 aaatatttta aggcacctcc actcttctta caacagaata cgatttaagt ttcctattag
     7141 aaatccaatg ttagatgaga ctaagtataa acatgagtca ctttataaaa ttataaaatc
     7201 aattatagaa aatgaagaag agtttcctgt atttgagggg ataagagaag aagaaatagg
     7261 atttatagca gcgtattttg gaggatattt aagagggtct agggataatg gtctaagaag
     7321 aaataaagtc ttactagttt gtcctaatgg tcttatggta tcaaagagtt tggaaataca
     7381 actatataaa tacataccaa ccatagaaat agtaggtata gtatccatta agcaactaaa
     7441 agaagtaaat gtatactacg attacataat tacaactata gatatacaaa atgtaaacaa
     7501 cgtaattgtt gtaaatcctc ttttaacatc atcagatgtt caattactta tgaacaaact
     7561 aataagtgta aaagaaaacg agaagtattt caatcttgaa ttaataatac aagctataag
     7621 aaaaaatgga gttatcaata atgaagaagc actaaaagct gatttattaa acataataca
     7681 caagatagat gaaggagaga tgtatcaacc aatgttaaag gaattaatta atgcagaaag
     7741 ggtcaatata ataaaaaatg ttagagattg gaaagaagca ataaaaatag cctcaaagcc
     7801 attgttagaa gataactcta tagaagagtt atatatagaa aatatgataa agtcagttga
     7861 gaaatatgga ccatatattg ttttagctga tagatttgct ctaccacatg caagttctaa
     7921 agaaggagta aacaagcttg ctatgtcttt actaatagta gaagatgaag ttgatttatt
     7981 aggaaaacca gtaaatatat ttatggtatt agctgctgta gataacacta ctcacattag
     8041 agcattagca tcactatcag agatgatgta cgaggaagaa aatgtaaaac taataattaa
     8101 tggtgataaa agttcaatac tagaacttat aaataagcaa aattaggagg aatgaaaaat
     8161 gaagatatta gcagtatgtg gttttggtgt aggttcatca atggtattaa aaatgacaat
     8221 acaaaaggct ctaaagcagt taggtataga atgtgaagta gaaaatacag atataaattc
     8281 agctagaggt gctgattgtg actgtatatt cacaagtcaa gaattgttaa atgaattaaa
     8341 aggaacttgt aatgtagatg tatatccagt taaaaagtac atggatttag cagaagtcac
     8401 agaagttgtt caaacttttt taagtgataa aaatgataag aaatagtata agttttaaaa
     8461 agtaaattta agttaatcag aataaaataa aaacttacta agttcaaaaa tagtaagaaa
     8521 gagaggaggg atttagtggt agaaaactta aacagttgac ctatcactaa aaaatataat
     8581 gcttgatttt atctcaaata atattttacg taatccatct atgttaattg gattaatagc
     8641 agcatttggt cttgtactac agaagaagaa agcatctgat gttataaagg ggtcactact
     8701 tgcagctttc ggaattataa ttatggagac tggaacaggt atgttagtta gttcaatagc
     8761 accaattaat ggagctttcc aaagtataag tggtggtgca gtaacaaaag gtttaagtga
     8821 tgttactttt actgcaagtt atggtggaat tataggttta gcaatgtttg cgggtttagc
     8881 tattcaccta atgatagcaa gatttactcc tattaagaca atcttcttaa caggtcacat
     8941 gctttattgg ttcccattca tatttgtagc ttcaggagtt gaagctggat taaatggtgg
     9001 agtattaata gcttttgcag cagtattatc agcactctat tggtcaataa tgccttggtt
     9061 attaagaaaa tatgtgtttg atgttatagg agatgattct tttacattag gtcatccatc
     9121 tggttgttta gcacttatat caggatttgt tgctaaatta gtaggaaata aagaaaaatc
     9181 tacagaagat ataaacatac ctcaaagttt atcatttttt agagaaatat ctataagtgg
     9241 tggaatggca gtgtttttaa tgtttatagt tgttgggata gtaataccag gtgcgtttaa
     9301 agatagtaat gagtttattg gaacgtatgc aataaagcaa ggtctttctt ttggagcagg
     9361 tcttataata atgcttcatg gggtaagaat gctaataaat caaataatgc cagcatttca
     9421 aggtatatct gaaaaagttg tgccaaatgc actacctgct tttgactgtc caatattatt
     9481 taattataaa ccaaatgctg tattaatagg atttttagtt gctatgctaa catctacagc
     9541 tatgatttta atatgtaact actttaatgt atttaatttg ctacttatac cacttgttat
     9601 aacttcattc tttgagtgtg gagcagcagc agtaatagga gaatcacaag gtggtatacg
     9661 tggagctata ataggtacag ctatagctgc aatatttatg gtagttttag taggaatatc
     9721 tgctgtaatt tactcaggaa ctattcaaaa ttggatacta atatttggag gtaatgacct
     9781 ttcattattt ggtataatca gtaggtttat aggttcacta tttggaggaa tattatagat
     9841 atgaaattta aatacataga tgagataaga agattaattg atataataga aaacgaagaa
     9901 aaagtcaata tggaaaaagc agtacaaatc cttgttgaag caatagaaag taaaaatgct
     9961 atattttcat ttggagcttc acatgcagga atattaacag aagaattatt ctatagagca
    10021 ggtggctgtg ttcttataaa tccagtattt gcaaaatctc taatgttaga tacagcacct
    10081 ataactcaca caagtaagat ggaaagatta gaaggatatg gtacagttct agctgataaa
    10141 actccaatta aaaaaggaga tgtagttata gttcattcag tatctggtag aaatccagta
    10201 agtatagagt ttgctatgaa agctaaggaa aataaggcaa tagtaatatg tataactaat
    10261 ttaagttatt caaaaagtgt atcttcaaga cattcttcag gaaaaaaact ttatgaagta
    10321 tgcgatttag tgatagataa tcatggtcaa aagggagatg cctgtgtaga gatagatgga
    10381 ttaaaccaaa aagttagtcc aacttctact gtaatagcaa ctactgtgat gaactctatt
    10441 atagctcaag ctactcagga attagttaat aaagggctaa agaatcctcc gattttctat
    10501 agtgccaata ttgatggtgg agatgagtta aataagaaga tttttgatga atataaaagt
    10561 gtaattcatt atgaatatta aggttaaaaa aatatgttaa tgaactttga agtttatcaa
    10621 caaagaatat taataatata taataaatgc tatcatttaa aagctgtagg taaaaatcta
    10681 cagcttttta ttattgtaga ttaaaaaggt gcgtaattaa attttaaatt ggagaaaata
    10741 aattggaagg tatcaattat aaatattaga aacgttgtca tagaaaaaaa ctatattaaa
    10801 aaaaagtaca tagaaaaaac tgattagaca ataaatacat gctttgataa tattttaaat
    10861 ggagtgaaaa tgtgtagaat tataatgaaa aaagaaaata aaaataaaaa aagaaaataa
    10921 aatggaggga ataaaagtgg gtatgttaaa aaaattatgt tcactaacta tggtagcaat
    10981 tatgactaca acacttataa cagggtgttc aagtggaaat ggaaaagatt caaaaaagga
    11041 tggcgaaaaa gaaaaactag ttctttggat gccaccagta gaaaataata tgaaggaagt
    11101 ttgggaccct attttagata aatttgagga aaaaaataac tgtgaagtag atttacagat
    11161 aattccttgg gataattatt ctgaaaaatt tgcaacagct ataagtgctg gcgaaggtcc
    11221 agatgtagga tatatgtatg cagaaatgta tccacagttt atagaaagtg gagcagtaga
    11281 agatttgact aattatgcaa ctaaagagga taaagagcaa tctatttata taaaaacatc
    11341 tgaaatgatg ggtggaatgt atggtatgcc attccaagca gcaaatccag gggtattata
    11401 ctataacaag gatattttag agaaattagg agaaaaacct cctaaaacat gggaagattt
    11461 taaaagaatt tgtaaaaaag caacacaaga tactgatggt gatggaaaga tagaccaatg
    11521 gggattagct cagggatggg gagctaaaac ttttggtaac ttaaactgga actggtatcc
    11581 ttatttatgg caagctggtg gagatatatt taatgatgat ttaaaatcgg ttaaatttaa
    11641 tgataagagt ggtttagaag cagctaattt cttaaaagaa ttacaagcat atgtgcctga
    11701 agattcttta tctaaagata gtaatgaaat gatagaaagc gtatttggac cagggaaagc
    11761 agcatttaca ataatgttat cttctgctgc aacaagtgta tttgatgaat cattcccgga
    11821 tttaaattgg ggatttgtaa ctggactaga agataagaaa gcagcaactt ttggagcagt
    11881 agaccattta tctttaatgt catctgctaa aaataaagaa cttgcataca agttaataca
    11941 acatatgtta agtgttgaat caatgacaga atttcataaa gcaataccaa gagcaccaat
    12001 aacaaaaggt gaaccatatc aaggtgatga aagattcaaa gaaatggtgg aaaatgacaa
    12061 aaatgtatat agaccattag tagtaggacc tcatggagtt gaaatatatg aatatttatg
    12121 gaaagaactt caaactatga tttcaggaga taaaactcca aaacaagcgt tagatgatgc
    12181 tgcaaaatat tcaaatgatt tattagcaca ataaaagttt aaagctgtaa tatgttgtaa
    12241 aggactttac agattaaaat tagcattgta tttataaata caatgctaat atttatattg
    12301 gagaggataa aatggaaaac ttagttagag agtttgaaga aaattcaaaa agaaaaaaaa
    12361 caaaattaaa tattaaacca tatatgtata tattgccatt gggaataatt ttagtggcgt
    12421 tttatgtgat accaataata atgtcaatat actttagttt tacaaagtat aatattatta
    12481 gtccagctac ttttataggt ttagaaaatt ataaaaaatt atttacagat gaaacattaa
    12541 aagtatctat tataaatact attaaattta ctgttgttgt agtaccttgc caaactatat
    12601 tatcattgat tttggctgtt tggattacag gaaaaggaaa tagtaaaata gcttcatttg
    12661 ctaaaggtgc tatatttata ccagtattat catctatggt tttgataggt atggtatgga
    12721 gggctttatt gaatggagaa ggttctatta tatatcaggt attaggtgcc tttggaatag
    12781 aatcatctaa acttttagga gatagtaaga cagcattacc tacacttatg tttatatcta
    12841 tgtggaaaaa tatagggtat ttcatggtaa tttatatttc agctataatg aatttaccaa
    12901 aacactgcta tgaagtagcg aaggttgatg gggctacaaa acttcaagaa tttataaaaa
    12961 taactgtacc tttattgaaa ccaactacaa taatggttgt atttttaggg tcgatatggt
    13021 cattacaagt atttgactta atttatactg tgacaggtgg aggtccaggt atatctacta
    13081 tgagtatagt tatgcatgca tttaacttaa actttaaaaa ctttaattct ggatatgcaa
    13141 tgactgtagc aaacgtatta tttttgttaa tagcagtagt ttcgatttta caaaataagc
    13201 ttgtaagacg agacaattca gatttttaga aaggtaggta taatatgaaa acagcaagaa
    13261 gattattaag tgatggttta cttttattta tagcgtgtgc aagtttggta ccttttatat
    13321 acatgttgat aatatcattg aagataacat ataactcata tagtttggat atatcttttt
    13381 caacagtaac ccttcaaaac tatatagata tttttactaa aaaaggattt gcacaatatt
    13441 tttttaatac agcaatagta tctttttcag gtgtattatt aaatttagta tttagtacat
    13501 tagcaggata ttcttttgcg aagatggatt ttaaaggtag tgataagtta tttttattta
    13561 tgataatgac tttaattata ccttcccaag ttacaatgat accactatat ataataatga
    13621 aacacttagg atggataaat agttatcttg cacttattat gccaatacca actgcatttg
    13681 gcgtatttat aatgagacaa gctattttag gagtaccaaa agagttatta gaatcagcaa
    13741 agatagatgg ttgctcggat tttagaattt taatacaaat agtgttgcct ttaattaaac
    13801 cagcattaat tacactagca atatttactt ttatgggagc atggaacgag tttatgtggc
    13861 ctcttatagc tacaactaaa gatgcaatga gaacattaac agttggatta tctactctta
    13921 agacattcca gataactaat tatggacaga tgatggcagg ggctacaata acatttttac
    13981 ctccatttat tttctatttg attttacaga gtaaatttgt tgaaggtgtg tctttgtctg
    14041 gtataaaagg ttaaatagtc taatttaata atatataaag aaacttatat aaatatggag
    14101 gaatttaaac tatggaaatt tcatatgtac tgaaagattg cacattcaaa cacaataaat
    14161 actcagttgt agaagctgaa acttggaaag ataaggattt ggatattgta gtagctaaag
    14221 gtgaaaaatt tgcatttcaa attatgttaa aagcaacaga agaatttaat tgtacaattg
    14281 ataaaagtag tgctatatca tggaaaggcc tgggaaatag agtaagatta gcattaaatg
    14341 tacctaatag tttagaaaat aattttagta taaatatact aggatatgtt caagatgata
    14401 caaaagcatt tgtgaatgat gctattttaa gggataaaga tatgttagta gagcaatact
    14461 tgcctcaaac attttgggtc gaaggtcaag ttccggaaga ttttgaagaa aataacttta
    14521 atataggtat tgatatattt aaaagctttg gatatgaaga tgaagaaaaa gcttgtacaa
    14581 ttgacgttcc tgtagaagta aaaaatgttg tattaaagcc tttagatgaa agtaagttct
    14641 ttttagattt atggcaacat ccaagctgtc tagctagaat gtataaagtt gagctatggt
    14701 ctgatataca ttttgaaata atcgataact atctaaaaga attagcttct ttaggagaaa
    14761 aagttgcaac aattatagtt tcagattatc catgggcagg gcaaagttgt tataaagttt
    14821 ataaaaatcc atcaaactta tatgaatata acatggtaag tgtatcaaaa ggattggatg
    14881 gaaagattaa atgtaacttt gagagtatgg ataggtatat aagcatagct gataagtata
    14941 aaatggctaa ggagatagat ttatttggtc tattaggtaa ttggtgtgct ggtgagtttg
    15001 gaaatcctgt agaaggttat aaggacccta taagagtaag atattttgat gaaaaggata
    15061 aagtatttaa atttataaac aatacaaatg atttaaaaga atatatagga ttagtattaa
    15121 atcatttaat agagtgtgga ttatgggaca gagtaaggat tatagctgat gaaccaaata
    15181 atccagaagt agtcaaagag tgtatagaat ttataaattc tactgtaagt actcatcaag
    15241 ttaaatataa atcagcaact cacgaccaaa actttttaga cagagctaaa gatgaaattg
    15301 atgatatgtc aataaattta aaacttacta tacaaaatta taaagatata gaaagtctta
    15361 agaaaaaaat caatgacaag ggtgggatat tgacttggtt tgtatgctgt tttccagaga
    15421 aaccaaatag ttttttaagt tctccttttg tagaaaatag aataatagga tggtatactt
    15481 attactttgg tcttgatgga tttttaagat gggactataa tttatggaca gaagaccctt
    15541 ggaaagattc aagttacaaa ttccctattt ggaaagctgg agatatgttc tttgtttatc
    15601 ctggaaaaga tttaaagcca gttagaagtg ttagaatgga gaatttaaga tttggaatac
    15661 aggactttga gttatttaca atgttagaaa aagaaaaggg aagagagtat atagaagttg
    15721 agcttatgca agaattatta aataaaaaag aaaatgctga aattaaaggt tttggtgaca
    15781 tagaactagg atattcactt gataattggg gatatgataa agttaaaaaa tatgtattag
    15841 agttgttaga cagagtataa aaaatataag agtgtctcaa aatgaacttt ttagttcatg
    15901 aggcactctt tttgtatgaa atcaatatag tttcattgtt tcaacaatga aaaataggat
    15961 tatttctatt ctaagacagc cctttagttt ttagttgtat tcaatgtttt aaaactaact
    16021 ataaacgcta taaagtttat aaatgacaat aattatatat aacatgatgt actttaattt
    16081 gctataatag ggattgaata atattatatg gaagataaca ttgtttgggg ggattaatat
    16141 aaaaagaata ggtattatta taatgttttt tttaagtata tcttttattg gattttatct
    16201 tgtaataaga gataacagtg atacagttaa gatgcaacga gggataaata taggtaatgc
    16261 actagaatca cctaaggatt ttccgtggga tgtaaaaatg tcaaataagt tttttgatga
    16321 tataaaagat gcaggttttg acacagtacg tataccagta aggttttctg attatacgtc
    16381 agattctgat aattttaaaa ttgatgaaga attttttaaa aagattgata aatatgtaga
    16441 ttatgcattg gataaagact taatagttgt gttggattta caccattttg aagaaattat
    16501 gaaagaacca agagttcata aagaaaagtt tttaaaaata tggcaacaga tagctaatag
    16561 gtatcaaaaa tatgataaaa aattggtatt tgaattatta aatgaaccta aagaaaattt
    16621 atattcacag ttactaaacg aatacattga agaagcaata aagataatta gaaaaactaa
    16681 ccctaaaaga actattatag taggaccata taatttctat caaattgatt atttgaatga
    16741 attaaatatt cctaaagatt ctaatatagt agtttccttt cactattacg agccaaatga
    16801 ttttgcattt caaggaaata tctatcataa gggatttgag cacttaagca atattacttg
    16861 ggaaggaaca aatgaacaaa tggattattt aaaaaaaagg tttgatactg tggaaaattg
    16921 ggcaaataaa aataaggtaa aaatcttctt gggtgaattt ggagtaacaa aagaagcacc
    16981 agaaacttca aggagagctt gggtaaaagc tgtaagagaa gaagctgaaa aacgaaactt
    17041 ttcatgggct tattgggagc ttgcttctgg atttggtata tacaatcaaa ttgaagggac
    17101 ttgggataga gaaatattaa gtgcattaat agaaaagagg tgattttatg aagaaaaatt
    17161 caaaaaagat acttataact ttaactatta ttactaatat agtatatata ttgtggagaa
    17221 ttttttatac agtacctaaa gaagaaggga tgtttgccct aatctgtgcc ataatacttc
    17281 tttttgtaga gataatgggc atgatggaaa tgtttgtgca ttattatggt atgtcaaata
    17341 ttgagtaccc tgaaaaacca atcataagtg aagaacttta tccacatgta gatgtattca
    17401 ttgcaacata taatgaatct gttgatttgg tgagaaaaac tgtaaatggg tgtattcata
    17461 tgcagtatcc agataagaaa aaggtacata tatacatatg tgatgatgga aatcgtgaag
    17521 aaatgtgtat tctagcagaa aaaatgggtg taaattacat aactagaact gaaagagaag
    17581 gagcaaaagc tggaaattta aataatgcaa tgcaacatac aaattcccct ttgattgcta
    17641 catttgatgc agatatgata ccaatgcatg actttttaat tgctacagta ccatactttt
    17701 tgaaaaatga gcaagctaaa aaagatggag aaaaagagga gtatgaaaag gttggttttg
    17761 tgcaaactcc acagagtttt tataatccag acttgtttca atttaatctg cactctgagc
    17821 gaaggattcc aaatgagcaa gattattttt acagagacat tcaattggct agaaatagga
    17881 caaattctgt aatttatggt ggtagtaata cagttatttc aagggaagca cttgaagaag
    17941 ttgatggatt ttatacttat tctattacag aagattttgc aacaggtatc ttaattcaaa
    18001 gtaaggggta tagatgttat gctattccag aagtacatgc atcaggttta tctccgacag
    18061 atttaaaaag tcttattaag caacgtgaaa gatgggcacg tggatgtata caaactggta
    18121 gacgtctaaa tattttgttt aggagaggtt taggtttttg gcagaaaata agttatattt
    18181 cttcaattac ttattggtat gcaagtataa aacgttttgt atatataatg gcacctattt
    18241 tattttctgt gtttaatgtg attgtagtaa aatgtacatt acttcaagta ttggtatttt
    18301 ggttgccaat gtatgtttta agtagtttat ctcttaaaat attttctcaa aatataagga
    18361 atgttagatg gaccaatata tatgaaacta taatgtttca gtccttaatg ccagcagtaa
    18421 tacttgaaac gtttgcaata tctaaaaata aattttcagt aacaaataag agtaaattag
    18481 aagaaaatag aatgtataag tttttacagg gaatacctta ttttatttac atggtcttat
    18541 ctatcatagg aattttaaaa atgtttgtag caatatttaa aatgagttcc ataacatatt
    18601 cagttgtatt attttggtta attggaaacc tttttaacct tgttatggct acattattta
    18661 tatcagggag acagcagtta agaaagtctg agcgttatat tgctgaaatt gattttaagt
    18721 taaagcaaaa ttcttatgtt ctttcttcaa aaacaattga tatatcagaa aatgggtttg
    18781 cgtttttgct agaaaatcca gaatatattt ccccagaaga agagtttgag gtagagttta
    18841 gagaaaaatc tggaaatgaa atgtatatag ctaatatgaa agcaaagatt gttaatgttg
    18901 tggaagtaaa ttcaaagtgg aaatatgcag cttatattac acatattgaa gatagtgaaa
    18961 tagataattg gatgtgtatt gttcacgata gaatacctac tttaccaatg acaatatcta
    19021 atcaactagg tttctttgat gatttgcaaa ttaatgtaaa aaaacgtatt gaaaaaacta
    19081 gaacattatc acgaagaagt ccaagaatca atatgaattt tcatatggat ataaaaaata
    19141 taggtaaatt aagaatagta aattttaatt atcaatatgt attattaaat tttgagaata
    19201 aaaatattta tcctaaagaa atagcattgg aaattagtga aggtattgta ctagaatgcg
    19261 atttatgtga gggtaaaatt gatgaaagag gtatcttata tagagtaaat aacattgaca
    19321 gcataatgca aaatttattt ttaagagatg aaatgatgga ttggatatta caaaataaga
    19381 aaattcttga ttcaaaacct aatgaaaaga aagaaaaaag tatagatgag tttgaaccca
    19441 tggaatatat ttaggagaga tgaaatgaag actttaaaag tgtttttttg ttctgcaaaa
    19501 tattttattt tagtgtttat tttttttata aatactactt ttataagttc agcaacaagt
    19561 gataaaattt tagatttgtc ctttaaaaag atagagactg acttaagttc taagattaca
    19621 tatgaagata caggtgtaaa aatagaaacg aacagttcta aaagtgataa gaaacgttat
    19681 ttatatattt accaaaatat gaaagaaaat tggagtatgt ataacaattt ttatattgaa
    19741 attcaaaata aaaataaaag ttctcagaaa ataaatttaa gcatacaaag taaaaatatg
    19801 cttgaattta gattaaaaga aggtagtgaa gtatttttag aagataaaaa tataatatat
    19861 tcagataaaa taaaagaagg atgcatagaa gtaccaggtg aatttgaagg caaaatttat
    19921 gtgaacttta atagccttat aaatgagaaa agtaatgttg tgctagactc aagtatgctt
    19981 tcaaacattg ttagttgggg aattacattt attccatctg atgaagaaca taataatatt
    20041 attataaaaa agatatcttt attgtctgaa gagaaattaa gttttttaca taatattaaa
    20101 ataactggca atgaagaagt acaaatacca gtattgggtc aaggtataag tcagtatgag
    20161 gtattaggtc ttgaaagtga ttctaaaatt aagtattctc ttataggaaa acaagataat
    20221 ttaagtattt ctcaaaaagg taaattaaca ttaaataata aatccaaacc tggacaaatt
    20281 attttacaag ttgacgttga tgataagttt aaaattggaa agaaaataac attaactgaa
    20341 tcttggagta ttaataaaaa agataaggat ggtgttccat atacattagt atctcctgag
    20401 caatcaccaa cagtacaaga tatgaaaaaa ataaacttta tgaataatat cataacgttt
    20461 gttcgaattt tatttgtatc tctagtaata atatgctttg gaatatattt atattggaaa
    20521 aaatgttcaa aaactaagta aagagaggag gttagattgt gttattttca agtttaattt
    20581 ttttatttta ttttttacct ataactttgg ttttatatta tgtatttagg tttaaccgaa
    20641 cgatacagaa catgatattg cttgctgtta gtttattttt ttatgcttgg ggagagccaa
    20701 aatttgttgt tatcatgata gtttccataa taatgaacta tatatttggt ttactggtag
    20761 atagatatag ggaaagtaaa ataaaagtga aagttttttt agttttgatg tgtgtataca
    20821 atataggtgt tttatttata tttaaatatc tagcttttgc gctaagaaat attagtgaac
    20881 ttattaatac tgaactaact atacctaata ttattttacc tataggaatt tcatttttta
    20941 catttcaagg aatgtcttat gttatagatg tatatcgtag acatggagaa gtccaaaaga
    21001 atccttttta tgtgggactg tatatagcat ttttcccaca attaatagca ggccctatag
    21061 ttagatatga gagtgtggca gaacaaattc tcaatagaaa agaaacttgg aataaatttt
    21121 ctattggtac ttgtaggttt ataacaggtc taggtaaaaa agtattaatt tcaaataaca
    21181 tggctatagt agcagactat atttacacta tgaatagtca aggagaaata gctgcatcac
    21241 ttgcatggct tggttcaata gcctatacta tgcaaatatt ctttgatttt tctgcttatt
    21301 cagatatggc tataggttta ggtcttatgt ttggttttaa atttgaagag aactttaatt
    21361 atccatatat atcaaaatca attagtgagt tttggagaag atggcacatt tctttgggaa
    21421 tgtggtttaa gagctatata tactttccgc ttggaggttc tagagtagca aataaagata
    21481 ttatgattag aaatatgttt atagtgtggt tatttactgg aatatggcat ggagcagaat
    21541 ggacatttgt aatttggggg attttaaact ttgttttcct aattatagag cgatttataa
    21601 tgtttgaaaa gattgaaaat cacaatttta taaaacatat ttatgcgtta ttagtagtta
    21661 attttgggtg ggtattgttt aggtcaccta atttaaaaga agcatataat tatttcaaag
    21721 ctatgcttgg aggcaatgga gttatatgga gtgattatac atatatgttt ttaaaagaat
    21781 actgggtttt ctttatattt gcatttattt ttagtgtgcc tattgcaaag aaaatcaata
    21841 agtttgttgt tgaacaagtt aagtatagta tgatatttaa tgtattttat ccaatctcag
    21901 ctattttatt gttctttatt tctgtgacat atttagtaac tggaagctat aatccattta
    21961 tttattttaa tttttagttg aggaggaaaa gtatgaatag attttttaaa gtaagattaa
    22021 taactgcaat tatgttctta gttgtcttat tcgctttctc tatatttaat atttgttatt
    22081 ctggaaaaga tatgatacag gagataaaaa attcagttgc tgaaaaaagt agtttaaaag
    22141 atacaatatc atctattgat aacacagtaa atgacaaagt aatatataaa aatacgttca
    22201 ttgaaactta tggctactta caaaaattaa tgggtaaaaa tgagttttca aaatttagtt
    22261 ctgtaaaaga tacttctgga aagatgcatt atacatattt tgctaaagct ccaaatccaa
    22321 ttggtgttat atcagataga gtaagaaaat tttctgaaga aatggaaaag caaaacacta
    22381 aattggttta cttaatgact ccagataagt atataaaagg agtgacaaaa tttccaaaag
    22441 ggatacctta ttcttatagc aatgagacag cagataattt tttaaatcaa ctaaaaaagt
    22501 ataatgtgga ctatattgat tttagagaaa atattttaaa gagtggtatt ccaaaagatg
    22561 atttattttt taaaacagac catcactgga aagtagaaac ttctttttgg gcatttgggg
    22621 aattaattga gcaacttaat aaaaaataca atataaattt agatgaaaat cattattata
    22681 gagataaaga aaattataat tcaattgtat atcctaagtc atttcttggt tctatgggaa
    22741 gaaagtctgg tattttatat ggtggtatag atgattttgc attaatttat cctaaattta
    22801 agactaatta tacttattat acagattcta aatttcaaaa atttgaatta aaaggaaggt
    22861 ttgaagagag tttgatatta tcatatcctt ttaatgcaga ccttaattta atggatggtc
    22921 aatcagataa atattctaca tatttattgg ggaatagacc attagttaaa ataaaaaata
    22981 tagaaaatcc agatggatta aaagtgctat ttgttaaaga ttctctaatt gtaccaacag
    23041 cagcattttt ttcctctgtt tgttcatcta tagatatgat agaccctaga tactatgatg
    23101 gagatatact agaatatgca aaatctcatg actatgactt tgtttttata tctatatatc
    23161 cccaaaatct tacaaaagaa ttttttccgt tttgtgagta aatttctaaa aaagttttct
    23221 gataaaataa atggctaact ggtaaaaagt tagccattta ttttgagtgt tattctaaga
    23281 aatatttttt ttactaaata cttctttatc tatttttcta agtgattttc ctacagtaat
    23341 tgatgatacc atagcaccat taacatttat catagtacgt cccatatcta gtatagggtc
    23401 tattgcaagt ataccaccaa ctaatggaaa ataagaacca agaccaactc cagagataac
    23461 aactgaaacg gccattgtag cagttcctgg aagaccagct attccaaacg aactaattgt
    23521 tataacaatt aacaacataa cataaaagct catatccatg tttactccag ccatattggc
    23581 aagtgttaca gccattaaag caggatatat acctgcacaa ccattcatac ccatatttgc
    23641 acctaaactt gctgtaaagc ttgatacacc ctcatcaact ccgtgatttt gtactagact
    23701 ttctatcgtt acaggcaatg ttcctaaact agaacgtgaa gtaaatgcca gaagtaaagc
    23761 ttcagttgaa ttttttatat aagtaatggg atttagacca tttaaagtta taaaaattaa
    23821 atgtataata aataatattg caactgatat ataaagagct aatataaact gtaaaacaga
    23881 tactattgaa ctaatacctt gtgaagttat tgtatttgca agcagagcaa ccacagcata
    23941 aggcataaat ttaataacag tcatagacac acttacaatt attttgtaag atgcttctat
    24001 aaaatctata aatggtttta ttgtttcaaa atgtttttta cttaatctct ttattgaggt
    24061 agctataaat gtagcaaata ttattgtagc tacaatattt ccatttgcca tagccattac
    24121 aggattagat ggcagtaatc ctcttaaagt atccacaaga gagtttattt ctttaagttc
    24181 ttgattttca actaaagtag gcatattagc tcctacacct aacttcatta tatttgcaac
    24241 gataattcca acaattgcag ctatagcagt agtagcaaga agcataccta aagatttaaa
    24301 tgtcagagtt ccaagattgt tatctttcat atttataatt acttttataa tggataagaa
    24361 aactaaaggt actactaaca tttttaataa gtccataaat ccagaaccaa ataggctata
    24421 ccacttactt acttcttgta gccaagtgac ttgagttgta tcattaggaa aaccagcaaa
    24481 agcttgtatt atgattccca atatgagtcc tagtactgta gcatatattg ttctcaatga
    24541 aaattttatt tttttctttt caaattgtct aacaataaag aacgtaccta gaagtaatat
    24601 tatgaaaaaa attgttttaa aatctgtaat cataagaaat tgtgataaaa atgaactttc
    24661 caatattttt ctccttttat ttaaaaataa atttttctaa gtttaaatga tatcaatata
    24721 ttaaaaaaat gtcaatatta tatcacaatt tacttaaata gagtaaaaca agttgatttt
    24781 gaaaaatgtg attaagtata gaaaaatagg gtataataaa tgtttaaaga atttgaattg
    24841 tggtaagaaa ataagaaata gcttttataa gatttgattt caaattaaaa tatgttaaat
    24901 aaataactaa aaattattat aaaaaatgtt ttcatagaat atatatcaaa tgaaaagctt
    24961 aaaataagtg aagaaattaa ctagacatca aaggagagat aaaatgagag taataataat
    25021 tggtggtgtt gcagctggta tgagtgctgc agcaaaatta aaaagaataa aacctgagta
    25081 tgaagttgtt gtttatgaaa aaactgaaat agtatctttt ggtgcttgtg gattaccata
    25141 ctttgttggt ggatttttta atgatgctga tgaattatta gcaagaacac cagagaaact
    25201 tagagaagct ggaattgatt taaatatatt tagagaagtc gttgaggttg atagtgaatc
    25261 taagaaaata aaagtaaaaa acataaaaac agatgaaata tatgaagatt actatgataa
    25321 attgatgata gcaactggag caagaagtat tatgcctcct ataaaaaaca taaaattgaa
    25381 gaatgtttct acattaaaaa gtttatatga tggagaatat ctaaaaaaac ttttaagtaa
    25441 tgaagataat aaaagagtga caataatagg agctggtttt atagggttag aagcagttga
    25501 ggcatgtaag aaattaggta aagatgtaga tgtaattcag ttagaagata gaatattgcc
    25561 acaagtattt gataaggaga tgacggatgt attagaagaa gaaataaata gacataatgt
    25621 taatttgcac ttggatgaaa tggttgtaga actttgtgga gaagataaag tagaaaaagt
    25681 tataacaaac aaaggggaaa tagatacaga tgtagtaata attgctactg gtgtgagacc
    25741 taataccgag tttttgtcaa atactaatat aaaaatgcta aaaaatggag ctatagtagt
    25801 tgatgagtat ggaagaactt ctgtagaaga tatatactct gctggagatt gtgcaactat
    25861 aaagaatata gtaagtaatg aaaatgtata tgttccttta gctactggag ctaataaatt
    25921 gggtaggata gtaggagaaa acctagcagg aagagaagta tcttatcaag gttcactatc
    25981 ttcaagttgt ataaaaatta tggatatgga ggcagcatca actggaatta cagaaaggca
    26041 agctaaagat ttaggcataa atgtcaaatc taaatttatt tctgattata atcaaactca
    26101 ttattatcca ggaagaaata aaatatatgt aaagcttatt tatgatgcag atacaaaagt
    26161 tattttaggc ggacaagtgg ctgggtttaa ggatgctgtc caaagagcaa atgtattggc
    26221 agctgctatc tttggaaaaa tgaccacaag tcaacttgga atgttagatt tatgttatgc
    26281 tccaccattt gcaagaacat gggatgtttt aaatgtagct ggaaatgtat ctaaataata
    26341 tttagattat atccaatata gttgacaagc aattaaggga atgaatttac ctaaactatt
    26401 tttataatgg taaaattcat tcctaaattt ttattccaaa tttttagaaa taaggcttct
    26461 attaaattat tcatcaaaat ttaaacgcaa gcttaatcta tcttctccaa gaatagtatt
    26521 ttcaaaaaca ttagtagcat tttctaaata catactaggt atgtctaaag aaggactaaa
    26581 atgagtcagt aaaagttgtt tgacatttcc aagttttgca agattagcag cttctctaaa
    26641 agtcatatgt ttgtttctaa cagcttttga tatatctaaa tcatcaccat acatggcttc
    26701 acatataaat aaatcactat cttttatgaa atctggtatt gattctatag gtcttgtatc
    26761 ggttgtaaga cttatcttaa ctccctttct caattctcct aagaccatat ctggagtgta
    26821 ttgttttgaa tctaaaacta tattttgacc ttcttggagt ttgttccata atattttagg
    26881 aacttcgttt ttagttgcct tatctatatc aaatttaggg tttcttctaa aattaaaact
    26941 gtatcctaaa cactctatag agtgttctaa actgattgtt gaaatttcta aatttcttaa
    27001 aactttatta tctaaagaaa aattgccttg agggttttct ataattttta aagtgtatgg
    27061 tacatattct actaaatttc tcatagaacg tatacaatcg actattccaa ctggaccaac
    27121 tatagttaaa tcacttgtac gaccactatt tccaattgtt gataaaagtc ctaaaagtcc
    27181 aaatatatgg tcaccatgta aatgggttat acaaatcaag tctatatctt taaagccaca
    27241 tttttttagc ttcatagata cctgagtacc ttcaccacag tcaattagta tttttctacc
    27301 tttatagttt ataaatacag aggatagaaa tctgtttggc ataggtacat ttccaccaca
    27361 tccaagtaaa gttaaatcta tcattttttc ccctttctaa aattaacaca aatctgttgt
    27421 ttgtttttat tatgatatcc tattataatt attttaacat taaatataac aataaatgtg
    27481 tatttgagtc aagaaatatt gtcaaataaa gtttttatat agaaatgtat aaaaatttgg
    27541 aaaacaaaaa gtgaaaatta tatttaggag catttaaagg aggaaaattt aatgaaagta
    27601 ttaaagaaaa ttactatttt gtcattgatt acattaacct tagttggttg tagtaacgga
    27661 gaagataaaa aagtggttga aggttctaag aaaattcaaa attctaaaaa agatgaacag
    27721 cctataatag tacataaaga tgcaaatata ttgaaagata ggtatgagcc accaaaagga
    27781 tttaaaagag ttgatgtaga aaaaggtagt tttgaatcat ttcttaggaa tactaagcta
    27841 aaaaattatg gagagaaagt aaagtattat gatggaagaa ctaaggaatc aaaaggtatt
    27901 tatgatagtg tatttgatgt tgatattggc aatagagatt tacatcaatg tgcagatgca
    27961 attatgctta tgagagcaga atacttgtat cagaataaac tatatgatga aataagtttt
    28021 gattttgttg atggttttaa ggcgaagtat tcaaaatggg cacaaggata tagaatttca
    28081 gtaaaagata gtggttcaag ctggtataaa gcaactgaat attcaacatc ttatgagagt
    28141 tttagaaagt ttatggatat agtgtttgca tattcaggaa cgttatctct tgaaaaagaa
    28201 ttggagcctg taaaagttga ggatatgaaa ataggagatg tgtttatagt tggtggaagt
    28261 ccaggacatg caagtataat tatggatatg gcagaaaatg aaaagactgg tgaaaaggta
    28321 tttatgatag cccaaagcta tatgcctgca caacaaacgc aacttcttat taatcgtaaa
    28381 aatccaaatt tgagtccttg gtatagttta gattttgaag gtgatttgac aatacctcaa
    28441 tggactttta aaagagacca gttgaaaaga ttttaaaata ataattttat ataataaaag
    28501 aaaaatatag atgtgaaaaa atgtaattag attaaaacta attggatatg gacaaaatta
    28561 aattgataga taaatattaa aaattacact aattaatctt actatagttt aatatttatc
    28621 taaaaagttt tatgtaaaat ataaatttta tattaaagct aaaactaatt tgaggaggct
    28681 aatttatatt gaagattaga aggtatttaa ttttggtaat tataattcta attacaacaa
    28741 gtcagagttt tatttcttat gggctagagc gatttgaaga aataaccatt tttcacacta
    28801 atgatataca tggaagatat gctgaaggtg atgaccatat acaaatagga aatctagcca
    28861 cattgaaaaa agaaactcca aactcaattt tagtagatgc aggagattgt ttgcatggac
    28921 ttccaatagt aaatatggat agagggaaaa gtgcaattga attaattaaa tgtgctggat
    28981 atgactatat tactcctgga aatcatgact ttaattatgg aaaagataga ctgtttgagt
    29041 tatctaaaag tgctaattta ggagagaata ctttaaaatt tttatcatca aatatttttg
    29101 aaaatggaaa aaaagttttt gatagtaatg atataaaaga aatagatgga ataaaaatag
    29161 gattttttgg actctcaacc caggaaacaa agagcaaaac tggatttaaa aatgtggaag
    29221 gattagagtt taaaaatcct atagaaagtg caacagaaca agtaaatgaa ttaaaaggaa
    29281 agggtgccaa tgtaatagtt gcaatatgtc atattggtac aaatagttta agtaagccaa
    29341 atagtataga tatagcaaat gaggttcaag gaattgattt gattattgat ggacacagcc
    29401 acactaagtt tgaaaatggt aaacaagtgg gtgatacatt gattgtaagt gcaggacaat
    29461 atttagaaaa tattggcgag ataaaactaa ctttggatac taatgatgta gaagatataa
    29521 aaatagaaaa taaatcagct aggttaattg gaaaagaaga agcattaaag tataagcttg
    29581 actccgctgt aagtaaaaag gttgataaaa taaaagaaca acaagaaaaa atattagata
    29641 aagttatagg ggtaactaca aatactctag atggttcata tgaaaatgta aggacaaaag
    29701 aaactaattt gggtaattta ataagtgaca ttttactaga taaaactaag gctgatattt
    29761 ctttatttaa tggagggaat attcgagata cgatagaaaa aggcaatata acaagaagag
    29821 atattgtaga tgtatttcct tttagcaata ctatagttac caaagaactt acaggagcac
    29881 agattaaaga tgtattggag catggagtaa aactttaccc agaaaaaagt tcagcctttt
    29941 tgcaagtggg aggaatttca tattacttta atcctaaaca aaaagaaggc gaaaaaataa
    30001 caaatattca aaaagaagga aagccattag atttaaataa aaagtatgta gttgcaacga
    30061 atgattatat agcatcaggt ggagatgaat ttccttgttt ttcaaaagag ccagtactaa
    30121 aggaatttgg aaatttagag agtgcagtca ttgaatatat agagtacaaa aaagaaatat
    30181 caaaaaatgt agatggaaga attggtatta aatctaaaga tgagttaata agcaagaatc
    30241 atgagagtga tttgatatta agtgaaaatg aaaaaaatat caatgataat gaagagaatc
    30301 tatctaataa tataaaaagc tctgatagtg ataaaaataa aagcttagat aaaacaagtg
    30361 ctagagaaag ttctaatcta ggaatatcta aaagagaagc taaagaaaaa tctcctaaaa
    30421 caggagattt aggtttttca aatagtataa ttatatttat agtttcaagt acattgatat
    30481 gtttattgaa ttttaatcaa aaagagttaa aggataaaaa gtcaaaataa aaattaatga
    30541 gcaaaaatta gtagatagta atttaatttt agataatagt aaacagcaaa ggaaattagt
    30601 tatataaata ctaatttcct ttgttttatg ttttaacatg attactttta aataaaattg
    30661 tattttatga aaaataatta cactaaatgg catagtatta tggggatttt tagtttttat
    30721 tcaagtaaat gaaatcatat taacaacttc tgatatattt acaaattgat aaaaaaatga
    30781 ttttattagt atgatataat ttagctagta tgtatgataa tggaggatat agggatgaat
    30841 aatatattac ttttggaaga tgacaaatct ttaaatagag gaattagttt taaattaaaa
    30901 aaagaaggat acaatgtttt tagtgcattt ggtatagaag aagcaaaaaa tattttcgca
    30961 aaagaagaga tatgcttaat tatttccgat ataggtctac ctgatggtag tggttttgac
    31021 ttttgtgagg agattagaaa gaaaagtgat gtttacataa taatgttgac agctcttgat
    31081 gaagaggtgg atattgtcac aggatatgat ttaggtgcag atgattatat cacaaagcct
    31141 tttagcttga tggtattaat atcaaaagtg aatgcgctta tgaaaagagt aaatacagta
    31201 aaaaattata ctctattagt ttgtgatgat ttattctttt attatataga aaataaatta
    31261 attataagaa cagatgataa ggaagaagag ataattttaa gtaagacaga gacaaaacta
    31321 ttaaaatatt tgatggaaaa ttctatgcag acattgacta aagagcaact gttagaatct
    31381 ttatgggata gtagtggtaa ttttgtagat gataatacga ttgcagtaaa tataagaaga
    31441 cttagacaaa aggttgaaaa aaatccatct gaacctaaat atataaaaac agtaagaggg
    31501 gttggatata tgtggggaga aaggagtata aaaaaatgct aaaaaatatg aacctcaaag
    31561 atggtttaag tgtgaaagat gattatataa tgagaagagt tattgtatat tctgttttat
    31621 ctgtactaat agtaaccatt gtatttatac tttttgaata tagcagatta cataaattgt
    31681 atgaacatca aataaaaaat actcaaaata ttgctggaat attgattgaa aaatatccta
    31741 atgatgaaat agatatagta aattctattt ataattctga ttatagtaag gtgtctactg
    31801 gagaaaaggc atttaagaaa tttggctatg gattggaaaa taaaatgtca aatgataaaa
    31861 attttagctt atacttaaaa tcttttttta aggaatcatt ttttattttt ttaatgatgt
    31921 ttatagtagt tataggtata atatattatt ttataagata cataaataaa agattgagta
    31981 aaatttattt tatagtagat aagatgtcac aagaaaacta cttgaaggac actactgagt
    32041 cagaagaaac tggttatcta gtagaatata atgaatactt taaagaaggc atatttagta
    32101 agataaataa ctgtctatat gagcttaata gaagtttaaa gataaagttt attaaattag
    32161 aaaaggaaaa agaaagtgta aaatcattag taacagatat ttcccatcaa ttaaaaactc
    32221 ctttagcatc cttaaaatta tacaatacat tacttataga agaagaatta gaagaagatg
    32281 aagccaacga gttcttatta accaataagg cttctataaa taaattagaa aatttaataa
    32341 attctttagt gaacatatca aggttagaaa ttagcatgat aaacataaaa aaagaagata
    32401 atgatataaa aaatactatt ctaaatgcag taaaaagtgt tacccctaag gctaagagca
    32461 aaagtataac attaaattta aatgaattta acagtagaat tataccacat gataaaaagt
    32521 ggactgagga gagcattttt aatgtattag acaatgctgt aaagtataca caggtaaatg
    32581 gagaaataaa tatatctgta gaagaaactg ctaatttctt taaaattata atagaggata
    32641 atggcatagg gattgaaaaa agtgagttta ataatatatt taaacgtttt tatagaggtt
    32701 ctgctgatga aattgaatct gtagaaggta gtggggtagg attgtattta agtagaaaga
    32761 ttttagaaga acaaggtgga aatattatag tttcttcaaa agtaggaata gggagcaagt
    32821 tttctttgtt tcttacaact atgtaatatt aaatgaaagg aaaatgtaag cctctacatt
    32881 tattatataa gtataaacag ctccagaaat aaaaaattaa taaaatatgg agtaatataa
    32941 cttagaatga gaggataatt ttatgaaaat actatatact gaaaatttat caaagcatta
    33001 tggaaaagga gaaagcttag taagagcttt ggacaatgtt gacttagaaa taaatgaagg
    33061 tgaatttgtt gcaataatag gaaaatcagg ttctggaaaa agtacacttt tgcatatgat
    33121 tggaggtctt gatataccta catctgggaa ggtgtatata gataataaaa atatatttac
    33181 attaaaagaa gaagaacttg ctgtatttag aagaagaaaa atagggttta tatttcaaag
    33241 ctataattta attccatctc ttaatgtatg ggaaaatgta gtgttgccaa tcggtttaga
    33301 tggtagagaa gtagatgaat cttttataaa agaactttta aaatcattag gacttgaaaa
    33361 taaacacgac gttttaccaa atacattatc aggtggtcaa caacaaaggg tggcaatagc
    33421 aagagcatta gctacaagac cagctataat acttgctgat gaaccaactg gaaacctaga
    33481 ttctaaaacg tctgatgagg ttatgagtat attaaaatct atgtctaaga agtacagtca
    33541 aactctagtt atgataactc atgatgacag tatagcccaa atggctgata gagttatatt
    33601 catagaagat ggcagggtgt caaaggttgg tgataaaaat gattaatact actaaaatag
    33661 caaaaagtaa tttaaagcaa aataaatcaa aaagtattct aataataatt actataatac
    33721 tttcaacctt aatgctttct tctattggaa tttatattgt tgatgcagga gcatatcaaa
    33781 aagaaaatac tataaagtat tcaggcaatt atcaaggtat attagcaaat gtagatgaaa
    33841 aacaggctga tatattgagt aatcatgcag atgttgaatt aactggtgaa atgaatggag
    33901 taggtgttga aaaactggaa gatgattcaa atatttctct agcatacatg aatgaagatg
    33961 ctttgaaatt aaatagtttt gaatttatca aaggaaaatt gccatcaaaa gagaatgaaa
    34021 ttgtgttaga tagtggagct ttaaaggcac ttggttataa aaataaagat ttaggtgaaa
    34081 agataaaaat atcttatgat gactataaaa gtgataaaaa aattgaaaaa gagttcatta
    34141 taagtggaat cttaaaaact agcgaaatat ctgaagcagg taaatattat tatgctatta
    34201 tatcagaatc atatatgaga aatactagag atatgtcgca agaagatttt aatatttatg
    34261 tgaaatttaa tgataaaagt aatttatcaa tagagcaagc aaaagaaaaa ttagataaaa
    34321 ttgctaatga tataggactg gatactatta atactgctgt aaatgaaaat tatataaatg
    34381 ctttaaaacc agatatggaa acgattatgg gtggagtttt tgtagggtta gtaattgtac
    34441 tatctagtat tttagtaata tacaatatat tttatatttc aatagttaca aaggttcaag
    34501 aatttggaaa acttagagca attggtgcaa ctaagaaaca aataaaaaat atagtgttta
    34561 aagaagggtt catattagcc ggaatagcaa taccaatagg aataatttta ggctatgtac
    34621 ttgcaaatat tataataaaa tcatttatgg atatagatgt aaaatcatca cgattaccag
    34681 ttatattatc ggttgtggta ataagcttta tatctgttgt tttatcactt ttaaaaccaa
    34741 tgaaagtagc atcaaaagta tccattgttg acgcagtaag atatacagga aataaaataa
    34801 gtaataagag taagagaaaa ggatataaaa atataaatct aaagagatta tcacatgcca
    34861 atttagaaag aaataaaaaa cgtacttaca tgacattggc atcacttata cttagtggaa
    34921 ctatatttat aacagtatca actgctttag aaagttttga tgctgagaaa atggcaagag
    34981 aacactttcc ttatgatata gaagttagac tatctggtta tgaaatgaac agtgataaaa
    35041 atcctaaaaa taatttgaat attttacaaa tgaataatcc tctaagtaaa gattttttta
    35101 atcaaataaa gaatatggaa ggaattaaaa gaatagaatc tgcaagaagt gtaaaaattg
    35161 gtatggagga ctatgatgtc gaatttaagt atgacctttt acaaagtata aatgaaaatg
    35221 atgtaaaatc attaaacaag aatataatag atggaaaaat aaatcttgaa agacttcaaa
    35281 ctggagatga aatagtaatt actcatgttg atacagcaaa agaaatggga gtaaaagcag
    35341 gagataaaat aagattaact ttatatgatg gagataaaaa gataaaaaaa gaatttaaag
    35401 ttcaagcaat agctatgggg gttccaagtt ttggtatagg aaaggatttt attgatagaa
    35461 ctttgaaata cgattcaact agtagcttgg gaatatatac agaagaagga aagtatcaag
    35521 aaatcaaaga tagtatcaag aagattgcta aaaataatgg atttttagag actgatttta
    35581 tagatagtag aattgagtca aataaggcta ctatttcatt tataaagata atgggataca
    35641 cgctaacagg cataataggt gtgattggat ttatgaatct tgtcaacaca atgataacta
    35701 gcatagttac tagaaaaaaa gaacttggta tgcttcaagc tattggtctt actaataaac
    35761 aattagtgaa aatgcttaat tcagaggcaa tgtattacac ttctggaatg atgataggaa
    35821 gtattctatt tggaggtata ttagggtata ttgctgttat atttctaaaa aagactggat
    35881 tatcttatgc aacatattct ttgccaatag taccaatctt gttgatgatt gtgtgtattc
    35941 ttatagctca atttataaca acttatttga taggacgaag ttttaataaa gaatctctta
    36001 ttgatagagt aagatacagt gaataaaatg caaatattta tggttagttt aactagcaaa
    36061 aaacatataa aaaaatatag ttaaagagat tcataattaa ataggttaaa gcatagtaca
    36121 gagcaaacaa tttaagcaga tgtttgctct gtattttatt atgtaatcaa taatatatct
    36181 aatatactga tattattcat gttagaaaat gtaccggtac aattctaaaa aagtataaaa
    36241 ttgtaccata taaaatgaaa attttgtata ataatcgtat agaaaataaa taggagctga
    36301 tatatatgaa taagaagatt aattatgcac caggaccaac tgaaactagg gaaaatgtaa
    36361 gattagcaag agcagaaaaa acaacaaatc cagatataga tattgatttt gttgaatttt
    36421 ataaaaagac atgcgagaag tttggtaata taattggaac aaaaaacgat gtttacatat
    36481 tgagtggtga aggaatatta ggtcttgaag cagcatgtgc atcacttaca gaaaaaggag
    36541 atagagtact tgtaattgac aatggtatat atggagaagg ttttaaagat tttgtaacaa
    36601 tgtatggtgg ggagtatgtg cttttttcaa gtgaatatac taaaagtata gatattgatg
    36661 aattgaaagc atttttagat gaggatagta attttaaata tgcaacagta gtgcattgtg
    36721 atactccaac tggcgtatta aatgatgtaa gcaaaatatg tccattactt aaagaatatg
    36781 gaatattaac tgtagttgat tctgtagcag gtatggtagg agaaagatta agtgtagatg
    36841 aatctaaaat agatataata ttaggtggtt cacaaaaagc tatttctgca ccagcaggac
    36901 ttactatagt cggaataagt caagatgcaa aaaattgtat aaaaaataga aaaactgatg
    36961 taataggttt ttattgtaat ttaaatatat gggaaggcta ttatgaaaaa aaatacttcc
    37021 cttatacaat gccaataagt gacataatgg ggcttgataa agcacttgat aatatattag
    37081 aagaaggaat agaaaatgta ttaaatagac atgaaaagat agcttatagt gttagaaaat
    37141 ctattgagga atatggtcta gaactatttt tagaagaagg atattctaat acagtcacag
    37201 ctataaaagt tcctgaaagt ataggagctt tagaacttac tgattatatg cttaaaaatt
    37261 ataatacact tgttgcaaca tcactaaatc aatatatgga tactatttta agaataggtc
    37321 atatgggaga gaatgcaaat ctaaataaaa tagaacatgt actaaatgtt ttggataaaa
    37381 gtttaagtgc attaggattc aaaggaaatg gaaatttgtt aaatttattt aataagtatt
    37441 atttttaata gataggggga tatagtatgg aagttacagt taagcaaaaa tttacaacga
    37501 aagacatggt ggaaacctca ctattaatag cattagtatt tattgcaact aaatttataa
    37561 acataagatt accaatatct ataaatggtg ggcttgtgca tttaggaact gcaatgttgt
    37621 tcatatcagc aatagtattt ggaggtaaaa aaggtgcttt atcaggggct attggtatgt
    37681 cactttttga tttgatatct gggtggactt tatgggcacc gtttaccttt atagttagag
    37741 gagttatggg ttatttactt ggaaagattg catgggcaaa tggtaataat gggaataatt
    37801 ttttaatcaa tgtaatagga atatgtgtct catcaatttg gatgctattt ggatattatg
    37861 taacagaagt tatactttat ggtaatttta tagtacctct tacttcaata ccaggtaatt
    37921 taatgcaagt attgataggt cttataatag cgcttcctat ttctaaggta ttgaaaaaat
    37981 gtataaaata aatataaagt gaactaaaat ttatgatagc ataaattata ctgtataata
    38041 ttaggatgga gtacataatt aaaaaatttt agtatagagg ttagttcaca atgttatcag
    38101 ttacaagata ttcaatcaaa aatgttcgtt taaagccgtg ggtaaagttt atttggtatt
    38161 ttgagacaaa atcaaatata ctgttaaata ataagttact tccgacagac agtatagata
    38221 ttattcttaa tctttctgat tttatggaat ataaaattga aaatcaagac tatactgcta
    38281 gtaatatgca ttttaatgga ataagggata aacatggatt tattattcaa catggaaata
    38341 tacgtgttat aggggtttct ttttatccat ttggtttata tccattttta aagataccaa
    38401 tttcagagtt taacagacaa attgttgacc tagaagcagt atcaaaacta tttgcaaaaa
    38461 aattagaaga gtcattaagt ccaacacaat cagtagaaaa agttgtttta tgtttagaag
    38521 aagtattatt atccatatta gaagaagatt taatttcaaa taaatatgta aagcttctaa
    38581 attcatttat atatgttaat agatatagca atataaaggc attttgtgat gatacaaata
    38641 taaatattaa aacattggaa agaatctgtt taaaatatac agggtataca cctaagattt
    38701 taaagagaat ttacagattt aaaatggcaa gcaatcaact tatttataat tataaagatg
    38761 atgaactttt tgattttatt tatgaaaatg agtactatga tcaagcacac tttataaaag
    38821 aatttaaaaa attttcaggg acgtcaccaa ttaaatttat tggtgagaat aagacgatta
    38881 aagaaaatat aaagtacagc tatttataat tatactgtcg attttttaca atacctccaa
    38941 tttatttttt gatatgatat aggaaaataa attggaggtt ttacatatga aaattattac
    39001 agaaatagtt gagtttaatg tggaagaaaa tttatcaaaa gaagagttta tagaaattgt
    39061 aaatgactta gaattaaaat ttcattctat tcaatctggt tttattgata ctgagctttt
    39121 atatgatgaa aagtctcaaa agtggattat gatacaacat tgggaatcta tagaagacct
    39181 caagagtgct tctagtaaaa tgtttaaaga ttcttcaact gagaaattta gaaaagcttt
    39241 aaagaatcaa actgttaaga tgaatataat accacaaatt aaaagttgga aattatagaa
    39301 ctgaatgtaa aagatagtta aatagtatca aactaaatta gccaaataac attttgtatt
    39361 taaattgtta tttggctttt agtgtttatt ttaatatgag tgttatatac tagaaaaacc
    39421 aacaaactgt tagagtgtgg attatcataa tgttatattc gggagctaaa aggcttaata
    39481 ctgatttgcc aattggtcaa tccatgcatg tccatctgga tatgctgtta ttaaagcatt
    39541 tacaagccaa tccctttgct cttgtgataa tagtgggact gttacatcga agtctttttg
    39601 ataaccaagc ctatctatgt atattgattt gcaaaacaaa accacttcgg gagccatata
    39661 tgggatatta tctgatgtta tcagtctggc tttatccata tctcttataa ttctttgatt
    39721 ttgggaaaaa agaaattttc catctttctg tggattatat atcaattcaa taaaatcgaa
    39781 ctgtaactgt tcgtcacact gtatattcat tttatagtta tcatcctcga ctttttttaa
    39841 ttcaataaat gagcaatcag gcttaatcgc aaaaacacaa atttgctcta tatgttgctt
    39901 gttaaggtcg ataataggtc gtaataaata attacccaag ggctcatata tatcccatcc
    39961 ttgattaagc atatactgaa tgctcttttc tttatctgtg tcagaaatcc atatgtcaat
    40021 atcactgtgt gggcgaatat gcatattcgc aaataattct agggcatatc caccacatat
    40081 tgaatatgaa aagccacaat cattaaaaaa gtttacacaa tctttaatta gtttgttcat
    40141 agcaacctcc ttttgcatgt actgaaataa attaaatttt taaaaatacc aactaaatgt
    40201 ttgttttgtg taaatataaa actgccgata ttaaggcagt tttatattta ctatttagaa
    40261 aatttattaa caaatttttg atattcacac attatcttat cattcataaa agaaataccc
    40321 ataaaagcag cttgctcacc aaacaaagta aaacgttcta tcatctgttg tggattacct
    40381 ggataaactg ttggaataca ccatgtgttt agaagaaaac caaacatttg agcagcaatc
    40441 tctggatttt taacttgcat agaattatct tgatttcctt cttcaattaa tgcttttatc
    40501 caaggcacaa tatcatttat aatctcatca aactgcgtag ctaaatactt aggattacgc
    40561 aatagtgatg atgacattaa aaaaatgtct tgtttattgt gttgttcata agcatgaagc
    40621 aacctatatt gtaatttttc taatgcggtc tttccttcat cattttttac atcatatcca
    40681 taaaatccat cattatacaa acgacttgtg attgccttaa ttatttcgtc ttttgattta
    40741 aagtgatgat aaatagcacc tcttgaaagg ccatctaaat tatctacaat atcttgaatc
    40801 gttgtctgct catacccttt ttctaagaac aacttatgtg aaatatcaag tattttttgt
    40861 atagtattat caggttcttt ttttcttccc aaaaaactca ctcctcaaaa caatcatttg
    40921 gtatgtttat cttagcaaat acataatgat ttgtcaatgt gtctttttag catgttgaac
    40981 aggtatattg ccatgatttc attattttat ttttttgcct tatactggac tatatttgca
    41041 gtttcctaat atatttggct catatttaaa taccattatc taaaagcact attgctgtac
    41101 gagaggcaat aggcatttta gaagaaggag gagttgagct aaagtataca tcataatctc
    41161 ttaagttttc tttttttgtg tttcctccaa actctaccat atcagtattt aatatcgttt
    41221 tgtagtttgt attttgaaac tttgaaatat caactgattg tattagatta gggtggaaat
    41281 taaatataaa taaatatttg cccttactgt acaccaaaat ctttttatca ttatccatat
    41341 gtataagttc atgactattt tggataaaaa tatcactgta ttttgtaagt tcgagcatag
    41401 atttatcaaa acttaataat tgtttatact ttaagttgtt atcttctgaa aggctccatt
    41461 gtcttctggc atacttatag ctccaattgt tgccttctcg tggaaaatca atccactcag
    41521 gatgtccaaa ttcatttccc ataaaattta gatatccttc acctgctaga gaaaaagtta
    41581 ttaatttaat taatttaata agagacattg ctctgttgat aacatggtta tttgagttta
    41641 tttccatatt ccagtacatt tccttgtcag ctagccaaaa aataattgtt ttatcgccaa
    41701 ctaatgcttg gtcatgggat tcacaatatc ctatattttt ttctccaggt cgtctagtag
    41761 taagttcata ccacattttg cccaaatccc agtcttcatc agataagtta gagatagttt
    41821 ttatccaaaa atcaggtact cccattgcga gtctatagtc aaatccaatt ccgccgtctt
    41881 ttatagggat acacatacca ggcattccac tcatatcttc tgcaatactt atcgaattag
    41941 gtttaatttc ttttattaat tcatttgcaa attggagata tgttatagct tcaatatctg
    42001 tattcatact aaaatatttt tcataactat caaatgaaac tccaagacca tggttatgat
    42061 ataacattga agtcacacca tcaaacctaa agccatcaaa atggtactca tttaaccaaa
    42121 attttatatt tgaaagcaaa aaatgtatta cttcaggttt accatagtta aaaagttttg
    42181 taccccaagc aggatgattt ccctttgaac ctgagtggaa aaattgatgt tcacttccat
    42241 caaactcatt tattccttct aaagtattct ttacagcatg agaatgaact aaatccaata
    42301 aaacagcaat ccccattgaa tgagcagtgt ttatgaggtt ttttaagtct tcaggagtac
    42361 caaacctaga tgagattgca taaaagtttg aaacttggta tccaaaagat gcataatatg
    42421 gatgttccat aatagccata agctgaatgg tattgtatcc agcttttttt atcttaggaa
    42481 gtattttttc agtaaattca ttataagttc caatagattc gctttcagta gacataccta
    42541 tatgacattc atagattagt ggagaagtta tgttttttaa gtcaaaatta ttgtcagtcc
    42601 agataaatgg agtttttggt tgccatattt gtccattaaa tccaccaaaa tctttttgaa
    42661 ttactctttt tatatataat ggtatacggt caaatgtttt tccatttgca gtaacttgta
    42721 cctttacctc tgatttgtga ggtaagctat tttgaccagg aataaatatt tcccaattac
    42781 cagacccaat ttttcttaga ggatgagatt ttctattcca attattaaag tcaccaatta
    42841 gtgacaaact atctgcattt ggagcccatt ccctatagaa gaatccatca tttgtctgat
    42901 gaaatccata gtaaagatga gcatttgcaa aagaactaaa atctttatag tttttcaatg
    42961 tttttgattt catatcctca taatgtttca ttcgcttttt tatatcagat tcaaatggtt
    43021 gtaggtatac atcaatatct aaaattttaa atcttttttg acttttcatt gtatttctcc
    43081 tccataataa atattacatc taaaaaataa tatttatctc atactatctt ctctgtataa
    43141 ttgatatata ttatataatc ctaataaaaa gcttaagcca ccaatgatta atttcataat
    43201 ttacctccct agtatttata cttatatatc gtattcatca aaatttaaaa gtttgtttaa
    43261 aactctttta ataatatcat aatcaaagcc tttataggaa agatgttgag aaattttttg
    43321 atatattttc tttttatctt ctttctttac tctttcatac cttttttttg ctagatacat
    43381 agcattttca aattcagtgt ccttgtctaa ttcagatact gcttcattga ttgtacttct
    43441 attgatacct ttattatata aattctgctt aattctgttt ttgccacatt tatttaggtt
    43501 aacatttgtg ttaacaattt tttgagctaa tacactgtca tttacgagat tataactttt
    43561 aagaaaatct atgaccctct caattatatt ttcatcaaat tctgatgata gtttttcttt
    43621 taattttttt tcagattggt cagcatgaga taaaatattt aatgctttat ttttagcttt
    43681 tatatacatt tcatcatcta aaataggttt taattcttct tcatttattt cactcccttt
    43741 ttttaaatta aatgtataaa caagttcttt aaatatagca ataaaaaatt tatcatctac
    43801 ataaatatta actctatcat catttctttt ttgttgttct atttttgtaa ttatacccat
    43861 aagtcctcct tttttatatg taattatatt aacaaaagca actaataaaa tttaacaaaa
    43921 aacttatatt tgtatgttat attttatcaa aattaagaca aaatagtaaa aagttatttt
    43981 tattaaaaag taaagcagaa tcatgttaaa taattatttt ttaaagtgtt ttttagcata
    44041 taaatataat tatataccca aaaaaacaaa ttataagctt taagaaataa aaaataatgg
    44101 tacaatagta ttataacatt aaaaggagac aaaatatgag aagtgaaaat ctagttaaga
    44161 tggcagagtt gaaaaatact gaaaaactag agaaatttaa tcgccataaa ggcaaaatca
    44221 aaataggtat attgggaggt acttttgacc ctatacacta tgctcattta gcaacagcag
    44281 aatttattag agacaagtat gacattgaca aaataatctt tataccatca ggaaatccac
    44341 cacataaatt atgtatcact acagataagt atgatagata taatatgaca cttctagcaa
    44401 ctgaaagcaa cgaagatttt ttagtttcaa aagtagaaat cgaaagaaag aaaaggactt
    44461 atacaataga tacattaaaa tacttaaaga aaaaatacaa aaatgcagac atttatttta
    44521 taacaggtgc agatgcaatt tgtagtgttg aagagtggaa agatgtaaag aaaaactttg
    44581 agttagctac ttttatagcc gcaactagac caggaattag tttgttaagg tcacaagaga
    44641 ctatagaaaa actaactaag aagtataatg ctgacattat aacagtttat gttccatcac
    44701 tggatatatc gtccacatat ataagggaac agctaaatga aggcaagtca atacgttact
    44761 tagtacccga aaatgtagaa aattatttat atgaaaataa actatatcaa tatggagatg
    44821 attaaatgaa cttagaaaat attaaccaaa gactaaatca aatgctacca gtggggaggc
    44881 ttagccattc aaaaaatgtt gcaaaatgtg ctgaaaaatt atgtgagatt tatggatgtg
    44941 acaaagaaaa agcttactta gcaggaatga ttcatgattg tgcaaagtat ttaagtgaca
    45001 aggaaataga ggattatgta aataagtatg aaatatattt agacccaata gaggatggaa
    45061 atcgttcctt gtctcatagt gtaattgggg cgtacatatg cgagtatgaa tttgaagtag
    45121 aagatgaaga tattataaat gcaatcaaat atcatacaac agggagagag gacatgtctc
    45181 ttttagaaaa aataatttac atagctgatt taattgaaga aggaagaaaa ttcccagttg
    45241 tagatacatt aagagaatta gcatatggag ggaagcttga tgaagcactt ttaacttctt
    45301 ttaataatac tttaatgttt gtcatcaata aaaaagaaga gatacatcca agaacagtta
    45361 tggcaagaaa ctatctaatt aaagaaaagt tattataaaa aagctatata aaggcaaaca
    45421 tattaataaa tttaaatttg actatgttac aaaatcgtat taatatgtta caataactaa
    45481 gtgtatttta attaggaaag tgaggaattt ttatatgaca gtggaacaaa tgacaaaaat
    45541 agcatatgat gccatagaag ataaactggg tcaagataca gttataataa atataggaaa
    45601 agtttctagt ttgtgtgatt attttattat tactacagca tcttctcaga gacaggtaaa
    45661 agctattgct gacaatgtag aagatgaatt agcaaaacta ggattagagc caagaggtaa
    45721 agaaggacaa ggaactcaaa cttgggtact ccttgattat ggagacataa tggttcatgt
    45781 atttaatgag gaaaatagag ggttttataa tttagaaaaa ttatggaaag atgcacctta
    45841 tatagatatt gacacattag cataaacatg ataatatatg ttattataat tagaaaattt
    45901 caaaaattat attaaattga atagactaga gcagtaaaag attatatttt ttcagagagt
    45961 tagtggaagg tgagaactaa tattatataa ctttgaactt actagattaa aatctattct
    46021 ccatggctgg attaaaagct atctaagaga gtctatatat gtagtaggct aattagggtg
    46081 gtaccgcgaa gatttatcct cgtccctaaa cgtaagttta gtgacgagga ttttttattt
    46141 tcaaagaatt atttggaaat tataagtaaa taatactaaa taaggtagtt atacacaatt
    46201 aaaaatagga ggcaaaatat gagcgtatat aattttaaag aagtagaatc gaaatggcaa
    46261 aaaatttgga aagataataa tcagtataaa atggatactg cacaaactga aaaacctaat
    46321 tattacacat tagaaatgtt cccttatcca tctggaaaaa tacacatggg acatgttaga
    46381 aattattcta taggtgatgt tgtcgcaaga ttcaaaaaaa tggaaggata taatgtactt
    46441 catccaatgg gatgggattc ttttggatta ccagctgaaa atgcagctat aaaacatgga
    46501 atacatccac ataaatggac aatggaaaat atagaagaaa tgaaagagca attaaattta
    46561 ttaggtatta gttatgattg ggataaagaa gttgcaactt caacgccaga atactataga
    46621 tttacacaag aaatattttt gaagttttta gagcatgggc ttgcatataa gaaaaaatca
    46681 tatgttaact ggtgtccttc ttgtgagact gttcttgcaa atgagcaagt tgttcaagga
    46741 gcatgtgaga gatgtaaagc aacagtatta aagaaagatt tagaacaatg gtattttaag
    46801 actactgagt ttgcagaaga attacttaat gacttagata cattagatgg atggccagaa
    46861 aaggttaaaa caatgcaaaa aaattggata ggtaaaagta caggagcaga tttagttttt
    46921 gatatagatg gaactgataa atctatgaca gtatttacaa ctagaccaga cacaacttat
    46981 ggagttactt atatggtact tgctccagag catgaattag ttaaagaatt ggttgcaggg
    47041 actgaatatg aagcagatgt tgaagctttt gttcaaaaaa tgcatactat gacagaaata
    47101 gaaagaacag cagctgatgt agaaaaagaa ggaatgttta taggtagata tgttataaat
    47161 cctttaaatg gcaagaaagt tcctctatgg atagctaact atgtattagt tgagtatgga
    47221 acgggtgcta taatggcagt tccagcacat gatgaaagag atagagattt tgctgaaaaa
    47281 tataatttag acataattga tgtaataaca gaagataaca aaatgataaa ttcagaagaa
    47341 tttaatggat tagatgcttc agaaggattt gaaggaataa tcgataagtt agaaaaagaa
    47401 ggtagaggaa agagaacaat taattataga cttagagact ggttagtttc aagacaaaga
    47461 tactggggtt gtcctatacc tgtggtttat tgtgatgaat gtggaatagt tccagttaaa
    47521 aaggaagatt taccagttct tttaccaaca gatgttgaat ttactggaaa aggggaatct
    47581 ccacttacga cttcaaagca atttatgtca acaacttgcc ctcactgtgg gaaaccagct
    47641 agaagggaag ttgatactat ggatacattc gttgattctt cttggtattt cttaagatat
    47701 gtggatagca ataatgaaaa tgaaccattt agtaaggaat tagttaatag atggcatcca
    47761 gtagaccaat atataggtgg agtagaacat gctataatgc atttgcttta tgcaagatgg
    47821 tttgtaaagg catttaagag tatgggaatg gtagacttca atgagccatt taaaaactta
    47881 cttactcaag gaatggtact tatggatggt tctaaaatga gtaagtctaa agggaataca
    47941 gtatctccta tggatataat agatgagtat ggagcagata ctgcaagact tttcgtatta
    48001 tttgcagcac caccagaaag agatttggac tggtcagagc aaggtgttga tggatgcttt
    48061 agattcttaa atagggttta tagattggtt gacgagttag cagatgtcgt taaaaaggat
    48121 gtagagtttg gagaattaaa ttcccaagat aaggatatga gatatactat acactctaca
    48181 cttaaaaaag ttactgctga tttaagtgaa aaatttggat ttaatactgc tatatcagct
    48241 cttatggaat taataaatga tatgtataaa tataaagagt tagataatat aaacgaagca
    48301 gttataaaag aaggtgtaca aactatagta actataattg caccatttgc ccctcattta
    48361 ggtgaagaac tatggactat gataggtaaa gaaggaagtg tatttgacat agactggcct
    48421 aaatatgacg aaaaagcttt agtaaaagat gaaatagaag ttgttgtaca agttaatgga
    48481 aaagttagag gaaaattaac tgttaactca aatatatcta aagatgagat ggaaaaggta
    48541 gctttagaag atgaaaaaat aaaaggatta gttgaaggta aaactatagt taaagttgta
    48601 gctgtaccta aaaaactagt aaatatagtt gttaaataac tcaaaaatat gaacaaaaat
    48661 ataaatttat aaaataaacg aggctgtctc aaaatagaga taagcctttt ttcattgttg
    48721 aaattataaa attgttgaaa ttataaaaat agatttgatt ttatacaaaa aaatgattaa
    48781 agaactaaaa agttcattct tatataccct agttgttgtt ttaaatatta ttataattaa
    48841 tgttaaatcg agttaatgta ttaagtggta tgtaaatcat tcagtttcca aagtgttgtt
    48901 catcaaggaa ctgctctaag cttaaacgaa aaaaatataa ttattgtatt ttgaaatttt
    48961 tttctatata atgaaaacag gcaaaaaagg tgcgtatcta tgctttatat gaaacaccca
    49021 gacaacgaaa ttcagattca tataatagct accatgtttc taaaaaggaa cttgtaaaaa
    49081 agatagcatt tcaacttccc agttgattaa aattatcagc aggaaaacaa gtatagtcag
    49141 cagtggtatt ctaatgggtg ttgtcgatat atccaagttg ggattgtctg aggatgttat
    49201 caaataactt gtgataggtg cagtagatgt ggagattcct gatacggatt tattctcagg
    49261 ggatggttgc ttcgggagat atggagcgta accagtttat tgatatggta accatttttt
    49321 tgtctaattt gatgaaagaa tcccaagaat accatacaga agtaagacag gaattaactg
    49381 gtggtataaa ctgataaagg caaatttaaa aattttgata ggatgatttt aagatttatc
    49441 ttctattttg ttttttagaa ataattgaaa tgttatgagg aggtatgtac aaatggagac
    49501 tgtaacaaat aatcaatcag gtgtagaaat tcaactcagt ctgtttgaag ctatcaaaga
    49561 tttattgtta attaatccta ttttcttgtt gggaattatc ttgattggta ttttcttagt
    49621 tgtaatattc aagaaaaata gtgatattcc aaaggtaaaa atatctattt tatcactggc
    49681 aatgtattac tacttatgtt taacactatc gcatattgtt ggtataccta cattcggtga
    49741 atatataaga ctgtcacagt taggggaaac gttctttaat ccaaacataa atcttattcc
    49801 ttttagtgat ggatttagtt tgagttttat tttgaatatt ttactttttg tcccattagg
    49861 ttttttatgt ccgcttataa gcaaaacctt tgaacgtttg agaaatacat tcttgattgg
    49921 ttttggatta tctcttttta tcgaaactat tcagcttttt acgttacaca gagcaaccga
    49981 tatagacgac ttactcacga acgtaattgg aacaataata ggctattttt gcttcaaact
    50041 gattgctaaa ttgcgaattg taaaactaca ttcagatgat gactctatgg aacaggatta
    50101 cacagtatgt attccgattg ccattataat agttgccctt atattaggat tttttagtta
    50161 agttccaaat agctaatttg ggaatccaga caatataaca gatactatgt taccttttac
    50221 aggagcatac tatctgttat attgtcaaca tcctatttta tggtttgtgt gtagtttcct
    50281 gtaaactgaa ctaaataatt aaatagaagc tattagaatt aataataaca gatagatatt
    50341 aataagcata aacaaatagt aaaatgtgta gatatagacg tttttaagtg aaactattat
    50401 aaaataattg actgacaatc aactgacaaa acctattttt ttaggtttaa ctgacattta
    50461 actgacagtc agtttttact atttaaatag aagttcgctt agattgtcgg aagcttcttt
    50521 gtccatttct ttaagtacat gagaatatct attcatagtt atttttatat ctgtatgacc
    50581 caatctttca gaaacaactt tcatattagt tccccctaaa agcagcagag tggcacttgt
    50641 atatcttaaa tcatgtattc taatcttttt taaattattt tttttgtaaa attgtgaaac
    50701 gtttttctta gtgaagaagg tagaaacgga tttaaattgg tgtttagaca aactaagtta
    50761 tttctgtttt ccaggatacc ttacaatttt aatttgcttt gtcttagttt ttcaattttt
    50821 caattaattc ttttggagct gataaagctc tttttgattt tggtcttttt ggctctttaa
    50881 aagatatttt gccattagaa tagacaagaa tttgattaac atttatcaga ttgttatcta
    50941 agtcaacatc tgaccaccta agcccaatag cttctcacat tcttaaacct agaagtaaca
    51001 ttaaaagaat aggtatttct atattattac caagtaactt ttctattagc aataatactt
    51061 cttctctatt gtatatttca tttgtagaat atttttcttt agaaggaagt tttataaaat
    51121 cacatgaatt ttcttgtatt tctcttaatc tatacgcttc ccttattaca gaacttagaa
    51181 agctatacct tactttagca ctagtaaagg tagaattatt aaagttataa tttacaaaag
    51241 cttgtactga actaggattt acttctgtga gttttagatt cttaaaaaag gttctatgta
    51301 atttttaacc caagattttg tatttgtaac agtatatgga gaccaattat ttttattcat
    51361 gtctatatat ttataacatc tttctacaaa tgtcatacct tttggagcaa caaacttatt
    51421 attatttata gtagatttta tttcaattaa atgtttttca gcatcctttt tcttttcata
    51481 acttccataa cttttctgtt ttatcttgcc agttgtttcc tctatgtact ccacatatac
    51541 atagaatttt tctcctcttt ttcttataaa agctgatttg atattcatat gtacactccc
    51601 tttataagtt agttttataa aagaacagtt ggactgctct aattatgtca ttatcttttt
    51661 aattctttac agttacatta taacacgtat ttgtatacac ttaaattaac aagaagataa
    51721 atatcgttaa aggaggaaaa gaaaatttaa tgtagaatta ttaagatata tagtatttca
    51781 tatataaaag ggggagatat tgtgaaatta aagaaattat tatcactagg gttagtgtca
    51841 atgtttgttg ctggttttcc tatatcagct aatgcacttg ataaaattga taaaattcaa
    51901 ggagcagata aatacgaaac tgctggtatc atagctgaca aacaaagtta tactactgca
    51961 atacttataa atgcagatag tacaatggct gatgggctaa gtgcgagtgg acttgcagga
    52021 gcaacaaatg caccaattct tttaactaag aaaaataata tacctaatgc aactcttaaa
    52081 agagtagaaa aagctaaaaa ggtatacata ataggaggag aaagttccat tgataaagca
    52141 acagaaactt ttctaacaga taaaggaata gagactagaa ggcttcaagg taatgatagg
    52201 attaagacaa gttataatgt agcaaaagaa ataaattcca ttaataaagt aaataaagta
    52261 atattaacta acgctttcaa aggtgagcca gatgctatga gtgctgcacc tgtagcagtt
    52321 agagataaag cagctatagt attaactgat ggaaaaagtg ttccatttaa tacaactggt
    52381 atagaaagtt atgcaatagg tggcacttca tcaatgagtg atagtttagt aaatgatact
    52441 aattcaactc gattgggtgg agtagataga tatgatacta ataaaaaaat agtaaataaa
    52501 ttctataatg gcgcaaaaga attttatata gctagtggta ctgatttagt ttatgcttta
    52561 gttggttcac caatggctaa aaataatcct attgtactag ttgatattgg aagtaataaa
    52621 gatatactta aaaatgctgc aaaagtaacc gggataggaa atctaagtga taaaattatg
    52681 ctagagtgtg aaaataccat caataatatt agtcttccat cttcaaataa aaatataata
    52741 tgtggattaa agattgattt tgattcaaat cacataattt ggcaagataa aggaagttat
    52801 cttgaatgtt atgatgataa ccttgaatat tatactgaaa aatataaaga cccaacagtt
    52861 cctataaata tagaaaatac aagtacacaa aatttagatg taacaaaatt aaaagtttat
    52921 ggagaagcta attcaacatt atatatgggg caatacgcta aaataaaaat ggattttaat
    52981 agttttggtg tattaaagcc aggagaaaaa tgtactattt atttagatat aatttcatta
    53041 gatccatcaa gaagcatgac attaacattt tcttatgtag gtgataaaga aaattataaa
    53101 tatgaacaag gattggcaag tagaatatta ttttataacc cagatggaga agattttttt
    53161 gaatataaat aactagtggg tatgtaaatt aataagggtt ttataagttt aattttttta
    53221 ttttcgtttt atattaacta tgtggtatgt aaatgtctcg atattgctca tatgttgagt
    53281 tattatattt agtttcatat gaactatatg aattttaaaa ttaaaaatac ttaaaaacat
    53341 ttactttaat agtaggtgtt tttttgatta aaagaatatt attataatgt aaaaagtaat
    53401 aaataggtaa aatatgtaag aattatatgt tataatattt ttagcaagaa gatgtaatct
    53461 acaatttata gagtggagtt catgtatcaa aaaattatcc tcccgacgtt aagaagggag
    53521 gtgaatatac atggataatt ttttacaagg catactagca agtctatctg ctagcttaat
    53581 agtttatata gctagcaaac tatttagaaa gcgtaaaaaa ccactcaaag cggcaactaa
    53641 gagtggttgg gaatttgatt taaaaatcag attccataaa actaagtaat ttctaaatta
    53701 tgaactccac tctacagcaa aatagattgt agttcttctt gcttttatta tatcacaaat
    53761 tggtacagat attcaaaaat aatattttta tgatataata aagtcataga aattttgcag
    53821 tgttcgattt tttgaagaaa ttaaggctta acagttgaaa tataaggcat tgaggacttg
    53881 tgataagtgt tatcaattgc actactcatg gttcactgca aatttgagag atttgtatat
    53941 gtgtaggcat tggaaatact caatttattt tggggtttta tattaactat atggaatgta
    54001 aataaatcat tttttgatat gtttaaatgt tcaataagct cgttttatat taactatatg
    54061 gaatgtaaat ggtaatataa aactcgacat agaagaatca caagatagtt ttatattaac
    54121 tatatggaat gtaaataaaa aaatgattta tatcccattt ctacaacttc tctagtttta
    54181 tattaactat atggaatgta aatagaatag aagaaaaatc agaatcacta cgatactcta
    54241 gttttatatt aactatatgg aatgtaaatg ctcttgtcgc agttgctccc gaagttgtta
    54301 atgttggttt tatattaact atatggaatg taaatacatc ttcgaagtca atagaatttt
    54361 ccccaagcac atgttttata ttaactatat ggaatgtaaa taatgaacta tctaaaccaa
    54421 ggtcataatt taattgagtt ttatattaac tatatggaat gtaaattgta tccaaaaaat
    54481 tacaataatc atacgaactg ctaatataag cagtcaatat atgtgtacat ttatccattt
    54541 tatctctaaa catataaatt attatccccc taaaaaactt tcataaaaac aaaaagaata
    54601 atatctcttt ggcaactggc tgacataact cataagatat ttatataagt cttagtccct
    54661 atagctttgc gtcactagat ttctctagtt ttgctgattt agttttattc tataactaaa
    54721 taatacaata gaattagtta ttattcaaca agattgtttg aaaattgaat aaatttatag
    54781 gtatgaacgt aatttcacac ttaaaaacag actaaatacg tagaatatat agaaaaattt
    54841 acctgtagtt tttgtgataa aaagctccta ttattaattt aagctagata agtttgagga
    54901 agtgacataa attgaaagaa ggaatatatt atgttgaata aaaaattacc agatgcagaa
    54961 ttaaaaatta tgaaatacat atggaatact ggttataaaa ctgtaatatc aaaaggtgtt
    55021 gcagattaaa tagaaaaaac atatgcttgg aagcatacaa ctacaattac acttttagct
    55081 agattaacta aaaaaggttt tttcatatcg cagagaattg ggaaacatgt acactataga
    55141 gtattaataa aagagaaaga atatctcaaa atagagggaa aaagaatttt tggaggtcta
    55201 cataacaatc cattatcaga actaatttca aaattacatg atggagaaga aataactgaa
    55261 gaaaaaataa tagaaatagg aaattggata aaaagctgga aagatgaaga ttaataaata
    55321 aaaggtagct actaatataa gtgctacctt ttttcttgtg gataatattg gggataagtt
    55381 gtgtaaaaat tgtggataaa atattttgct gacatttaac tgacataagt attagatttt
    55441 gatttaaaaa tgttgaaata tcaataaata attaaataga agttattaga attaacaata
    55501 gattcctttt tcaaagaagt ctttgatttc atcaaggtta tcagtttttc caagtgctaa
    55561 gataagtttt attctagctt tttgacctgg taagtcccca ccaaatatac aaccaagatt
    55621 ttttaaatct ctaccagaac caaagtaacc ataactatcg aatactctac ctgaatgaca
    55681 tctagaaact ataactacag gaagtccttt ttctctagca tattcaactc cagaaagcat
    55741 ttgaggagga atattacctc tgcccattgc ctcaataact atacctttat aaccactatc
    55801 aacagcaaat cttataaagt cagcattttc tcctacatat gctttaaata aggcaacttt
    55861 agattctacc ttatcagtat ctataattgt tctatttaca atatctcttg taaggacaag
    55921 ttcgttgcag tcaattattc ccaatggacc actagttaga gatttaaatg tatttagaga
    55981 aagagtattt gttttagtag cttcagaagc taataatact tcattgttta aaactacaag
    56041 gactcctttt cccatagcat ctttggatac tgcagtacaa actgatgcag ataaattact
    56101 tgaaccatca tatccaagtt cagaactact tctcatagca cctgtgacta ttacaggttt
    56161 gatgttgtca attgtaaggt ctagaaaata agctgtttcc tctaaactat ctgtaccatg
    56221 tgttattaca acacctgtaa tatcttttct tgctaataaa tcatttacat agtttttcaa
    56281 ttccatcatt ctataaggtg ttatgtgagg tcctggaatt tcatcaaaat taaaaacttc
    56341 aacatctgca actttatcaa tgttggtaac cattgatagt atttgttcac ctgataaagt
    56401 tggtatagct gctccgactt tatcatctac tgtcatagat atagttccac cagtaaaaac
    56461 tatggcaact tttttcttaa tactcatact attctctgcc tttcataaat aaaatttata
    56521 attccgatag gattatatca aaaaaagtag ttaaggtcta cataaactct tttattcata
    56581 taatttagat atttcagtgt aatataatta tttcttaatt tttttccatt caacgatata
    56641 accatttaat atctctctta tggcttttcc tatcttagta taagcttcat catatagatt
    56701 tgctagagat attctaattg accattcagg gccatagaat ccatttccac tgagtaaaac
    56761 tactgaatag tcattagcta atttataaag aacatctact ggagatgcat ttttacttat
    56821 aaatttaaat aagtcttctc cgtagtttaa tttagcccat tcttcaatat caaattgagt
    56881 gtaatatgca gcattgtttt tgttttcatt aattggaagc tctaaagctt caaataatag
    56941 tttttgacgt ctatggcaga tactcatatt gagttttttg taggcatcta ctttgtcaat
    57001 caatgcaaaa gcagagaaaa atgccatttg tacttgctgt ggagtagaaa gaccagcagt
    57061 atggttgaga gcaacaagtc tgctatcagc aacaactctt tccataaatg aaaggctaga
    57121 agggttaaga ctcatatcac tgtaacgctt atctactgat ttttttaatt ctccagttaa
    57181 atcatttatt ttcttatcaa aaacattttt cttatgaagg gcaaatgtac caagtctcca
    57241 tcctgtaact ccaaaatatt ttgaataaga atatactcca acagtgttgt aaggtagttt
    57301 tgacattaag gatgaaaaat cttctacaaa agttccatat acatcatctg atattatcat
    57361 taaatcttta ttataatttt caattacatc tattagatta ttacaagatg tttcatccat
    57421 agctatagaa gcaggattat taggattaac aacgaataaa gctttaatag atttgtcacg
    57481 aagtttctct aattcttttt ttgtatattg ccatgtgtga gcaccttttt catcaacttc
    57541 attagcattt atatttacca ctttaaagtc gtaacgagga aggttaggta tttcaaggta
    57601 aggtgtaaat attggagtca ttaaggctat tgtatctcct ttttttagaa gttcatttgc
    57661 cattaatgaa tcaaatatat agcacatagc agctgtagca ccttcaacag caaaaatttc
    57721 tacatcacca tatttacctg atatatcata tttcatttct tgaactaggt aatcgtgtac
    57781 tattttttcc atatgaggta acattctatc tggaagtgga tagttatcac caataattcc
    57841 atcagctagt tcatgaacaa attcatctcc atcaaatcca agttcattta taccaaagtt
    57901 tataatatct ctagctaaat atgctccagg catatctata ttttcattta taaatttaaa
    57961 aaatctttct ttaataccct ttttttgagg cattccagcc aaatgaccta aatcccaatt
    58021 agaacgagtt tcagtaatag cgaaatgacc aaaagtaaaa aaggcttctc tagcagttga
    58081 acaagtccag tttggatttc cacgacctgc atcaagtaat tctctgttat tttcttttgc
    58141 agtgtatttt gcaatatcta ttaatttgtc cttaaattca aaagggctta tttttccata
    58201 tatgtttttg atttctttat aagtatgatt tttcatgtta aattcctcct tatgtaataa
    58261 gtttcacatt tttataataa aataaacaag ttgcaaaaat gattatactt taattataat
    58321 aggtttatag aaaaagtaaa gtatgaaatt aaaataataa ctctatttag ccttattaaa
    58381 tatatgttaa aataaaaaat accttttaat aaaaaatgat tgttatataa aataaatatt
    58441 caatttaatt atcaccttag tttttttat
//
LOCUS       DAEQAF010000011        58267 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.011, whole genome shotgun sequence.
ACCESSION   DAEQAF010000011 DAEQAF010000000
VERSION     DAEQAF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58267
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.011"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(202..1041)
                     /locus_tag="KRN00_000827"
     CDS             complement(202..1041)
                     /locus_tag="KRN00_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1826706.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKDELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMFILIVVGAITGIL
                     GLF"
     gene            complement(1065..1823)
                     /locus_tag="KRN00_000828"
     CDS             complement(1065..1823)
                     /locus_tag="KRN00_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1826707.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(1870..2343)
                     /locus_tag="KRN00_000829"
     CDS             complement(1870..2343)
                     /locus_tag="KRN00_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1826708.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITLAKRIIIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSYNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(2372..2788)
                     /locus_tag="KRN00_000830"
     CDS             complement(2372..2788)
                     /locus_tag="KRN00_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1826709.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(2835..3887)
                     /locus_tag="KRN00_000831"
     CDS             complement(2835..3887)
                     /locus_tag="KRN00_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1826710.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            4283..4963
                     /locus_tag="KRN00_000832"
     CDS             4283..4963
                     /locus_tag="KRN00_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH1826711.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(5096..5416)
                     /gene="sugE"
                     /locus_tag="KRN00_000833"
     CDS             complement(5096..5416)
                     /gene="sugE"
                     /locus_tag="KRN00_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBH1826712.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            5798..6625
                     /locus_tag="KRN00_000834"
     CDS             5798..6625
                     /locus_tag="KRN00_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH1826713.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGAKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGSLIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEHGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            7446..8120
                     /locus_tag="KRN00_000835"
     CDS             7446..8120
                     /locus_tag="KRN00_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826714.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRIWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            8108..9268
                     /locus_tag="KRN00_000836"
     CDS             8108..9268
                     /locus_tag="KRN00_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1826715.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASALTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKSQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            9485..10012
                     /locus_tag="KRN00_000837"
     CDS             9485..10012
                     /locus_tag="KRN00_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBH1826716.1"
                     /translation="MKSFANNITFSRIVFALLMLSSTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFAVTILVTVGKNIALPMYLWWCIVAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            10298..10966
                     /locus_tag="KRN00_000838"
     CDS             10298..10966
                     /locus_tag="KRN00_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826717.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            10969..13437
                     /locus_tag="KRN00_000839"
     CDS             10969..13437
                     /locus_tag="KRN00_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826718.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIRKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYILSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSFISALPSAIYASHVSPKIAMVGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNVLDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITDSILEDFK
                     NGSICFIKNPIAISTPGVKTRHTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNSSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLAC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(13677..15101)
                     /locus_tag="KRN00_000840"
     CDS             complement(13677..15101)
                     /locus_tag="KRN00_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1826719.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(15120..15812)
                     /locus_tag="KRN00_000841"
     CDS             complement(15120..15812)
                     /locus_tag="KRN00_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826720.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(15867..16643)
                     /locus_tag="KRN00_000842"
     CDS             complement(15867..16643)
                     /locus_tag="KRN00_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBH1826721.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSY"
     gene            complement(16640..17410)
                     /locus_tag="KRN00_000843"
     CDS             complement(16640..17410)
                     /locus_tag="KRN00_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBH1826722.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQSLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIVVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(17407..18111)
                     /locus_tag="KRN00_000844"
     CDS             complement(17407..18111)
                     /locus_tag="KRN00_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1826723.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(18366..18878)
                     /locus_tag="KRN00_000845"
     CDS             complement(18366..18878)
                     /locus_tag="KRN00_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826724.1"
                     /translation="MKKISQEKISTHIQEIPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMEFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            19204..19461
                     /locus_tag="KRN00_000846"
     CDS             19204..19461
                     /locus_tag="KRN00_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826725.1"
                     /translation="MILNRTELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            19604..20230
                     /locus_tag="KRN00_000847"
     CDS             19604..20230
                     /locus_tag="KRN00_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HBH1826726.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIKVSNINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(20477..21256)
                     /locus_tag="KRN00_000848"
     CDS             complement(20477..21256)
                     /locus_tag="KRN00_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1826727.1"
                     /translation="MNSKIYYFSRTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(21324..21785)
                     /locus_tag="KRN00_000849"
     CDS             complement(21324..21785)
                     /locus_tag="KRN00_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1826728.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(21761..22438)
                     /locus_tag="KRN00_000850"
     CDS             complement(21761..22438)
                     /locus_tag="KRN00_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1826729.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            22671..23057
                     /locus_tag="KRN00_000851"
     CDS             22671..23057
                     /locus_tag="KRN00_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1826730.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            23060..24859
                     /locus_tag="KRN00_000852"
     CDS             23060..24859
                     /locus_tag="KRN00_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBH1826731.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLISWIIGILIMIAITIHCNIKIKNMKKSIQILRDDEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLNKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKAFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLKQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(25214..27088)
                     /locus_tag="KRN00_000853"
     CDS             complement(25214..27088)
                     /locus_tag="KRN00_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1826732.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVSPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDISKDVKIGQRICVE
                     "
     gene            complement(27093..28757)
                     /locus_tag="KRN00_000854"
     CDS             complement(27093..28757)
                     /locus_tag="KRN00_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBH1826733.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDEGYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKAFHAVLLKVR"
     gene            complement(28771..29592)
                     /locus_tag="KRN00_000855"
     CDS             complement(28771..29592)
                     /locus_tag="KRN00_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1826734.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(29691..30455)
                     /locus_tag="KRN00_000856"
     CDS             complement(29691..30455)
                     /locus_tag="KRN00_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1826735.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(30452..31201)
                     /locus_tag="KRN00_000857"
     CDS             complement(30452..31201)
                     /locus_tag="KRN00_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1826736.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KSDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIKYRRRKE"
     gene            complement(31705..32310)
                     /locus_tag="KRN00_000858"
     CDS             complement(31705..32310)
                     /locus_tag="KRN00_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1826737.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEDVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMMKSIRELDNLKYEWICMSHGTPCIK"
     gene            32489..33127
                     /locus_tag="KRN00_000859"
     CDS             32489..33127
                     /locus_tag="KRN00_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1826738.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            33259..33921
                     /locus_tag="KRN00_000860"
     CDS             33259..33921
                     /locus_tag="KRN00_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826739.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DN"
     gene            33921..35102
                     /locus_tag="KRN00_000861"
     CDS             33921..35102
                     /locus_tag="KRN00_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1826740.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTIHAENCHNGGARFIIKFY
                     T"
     gene            complement(35283..37943)
                     /locus_tag="KRN00_000862"
     CDS             complement(35283..37943)
                     /locus_tag="KRN00_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1826741.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATLEYWDSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGDRI
                     LNGKPLEPIAPKSKGESFKKISETTLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKLLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYINSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKNIASSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQISVDPKLFYDTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(37940..38623)
                     /locus_tag="KRN00_000863"
     CDS             complement(37940..38623)
                     /locus_tag="KRN00_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826742.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(38967..39920)
                     /gene="blaCDD"
                     /locus_tag="KRN00_000864"
     CDS             complement(38967..39920)
                     /gene="blaCDD"
                     /locus_tag="KRN00_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH1826743.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLINKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGYTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(40461..42575)
                     /locus_tag="KRN00_000865"
     CDS             complement(40461..42575)
                     /locus_tag="KRN00_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBH1826744.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            complement(42833..43693)
                     /locus_tag="KRN00_000866"
     CDS             complement(42833..43693)
                     /locus_tag="KRN00_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826745.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASISDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            complement(44304..44933)
                     /locus_tag="KRN00_000867"
     CDS             complement(44304..44933)
                     /locus_tag="KRN00_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1826746.1"
                     /translation="MDYKEIVFDVDGTWIDTEYAILHSLQDTIKQINRKIIPIKELSF
                     ALGITGEDALRYLKIEDITIALSMWDRNMEKYKNTVLVFKEIKEMLTELIKLNIGIGI
                     VTSKTHEEFRNDFLSFDIAPYFNTVVCSNDTLEHKPKAVPLLKYMELTKCQNNELLYI
                     GDSIYDMQCAYRANVDFGLVKWGSGDRVSAVISFTTPLDLIRQLSVSSN"
     gene            complement(44953..45567)
                     /locus_tag="KRN00_000868"
     CDS             complement(44953..45567)
                     /locus_tag="KRN00_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1826747.1"
                     /translation="MNEKWLEWAIELQSIAQAGITYGKDIYDIERYERIREISAEMIA
                     YKTDISTEKVRNLFCNESGYQTPKLDTRAVIFENGKILLVKENTGKWSLPGGWVEVNL
                     SVKENTIKEVKEEAGLDITADRIIAIQDRAKHNLPIYAYGVCKIFVLCTVIGGTFKEN
                     IETTEFSYFSENELPELATEKNTEEQIKMCFEACRTDTWTVIFD"
     gene            complement(45635..45997)
                     /locus_tag="KRN00_000869"
     CDS             complement(45635..45997)
                     /locus_tag="KRN00_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1826748.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHLDGTIIEYVQHTKQD"
     gene            complement(46295..46759)
                     /locus_tag="KRN00_000870"
     CDS             complement(46295..46759)
                     /locus_tag="KRN00_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1826749.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(47023..48444)
                     /gene="nhaC"
                     /locus_tag="KRN00_000871"
     CDS             complement(47023..48444)
                     /gene="nhaC"
                     /locus_tag="KRN00_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH1826750.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(48474..49538)
                     /locus_tag="KRN00_000872"
     CDS             complement(48474..49538)
                     /locus_tag="KRN00_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBH1826751.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            complement(49523..50932)
                     /locus_tag="KRN00_000873"
     CDS             complement(49523..50932)
                     /locus_tag="KRN00_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBH1826752.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIKYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     FKLLLKSLNFEEERLCILG"
     gene            complement(50932..53136)
                     /locus_tag="KRN00_000874"
     CDS             complement(50932..53136)
                     /locus_tag="KRN00_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH1826753.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKNNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(53130..53504)
                     /locus_tag="KRN00_000875"
     CDS             complement(53130..53504)
                     /locus_tag="KRN00_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBH1826754.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(53582..55012)
                     /locus_tag="KRN00_000876"
     CDS             complement(53582..55012)
                     /locus_tag="KRN00_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBH1826755.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(55005..55313)
                     /locus_tag="KRN00_000877"
     CDS             complement(55005..55313)
                     /locus_tag="KRN00_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBH1826756.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(55457..56524)
                     /locus_tag="KRN00_000878"
     CDS             complement(55457..56524)
                     /locus_tag="KRN00_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBH1826757.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(56780..58153)
                     /locus_tag="KRN00_000879"
     CDS             complement(56780..58153)
                     /locus_tag="KRN00_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1826758.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILANSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
BASE COUNT        19653 a         9999 c         7033 g        21582 t
ORIGIN      
        1 tgaaaaagca cctcattctg attaaaaatc tttctgagat actttttaaa atattaaata
       61 ctacatatag cttacataag tttaaaattt aatctattat aaaattaccc taattgccaa
      121 actttttaat ataaattttc caacatccta caaatataat caatagatat agaatcctaa
      181 cttacaccaa tatatattta tttaaaatag tcctaaaata cctgtaatag ctcccactac
      241 tatcagtata aacattattt ttattggaga aagacctttt tttaaagcaa agagtactaa
      301 taaagtaagt accaaaggaa ttaatcctgg aaatatctta tcaagtaaat ccgtttgaag
      361 actaaattta aaatcaccac tagtataact tattggtgta gataaattaa taaacctacc
      421 tacaagtccc cccatgacta aggtacctag tatagaagcc ccttctataa ccttatttac
      481 tattccacct tgaagtatac tttcaacagc ttttttccca tacttatatc catttgtcca
      541 cattccaaaa gaaattgaag tcattattat atattgagct attacaaata atataggtcc
      601 tgcaattgat gctcctccct cagttaaacc aatacaaaca gctaacacta taggagttat
      661 aactccttga gttaaagtat cgccaattcc tgctagtgga cccatcaagc ctgttttgat
      721 agcattcata ccatctccac ttatttcatc tgctccatta gctttttctt cttccatagc
      781 tattgttatt ccatgtataa cacatccaca tataggttct gtgttaaaaa atgctagatg
      841 agtctccact tcttgtttta actcatcctt atctggatat aattttttaa gtactggcaa
      901 cattgaatgt gaaaaagctg ttgattgcaa tctttcataa ttgtaattag attgtgcaaa
      961 gaaaaaccat cttaaccatg attttattac atctttcttg cttaacgttt tcttagatac
     1021 ttcatttttt atatctgaca taatattttc cccctcacat gtatttaaga tgtagcacta
     1081 tcttttccgt acttaattga agtaattgta agagcaagta ttactccaat aacagatatt
     1141 actattatat ctactttaaa ataaacagcc attagtattc ctaatatgaa aaagggcata
     1201 gtaaacttgt ttccaatcaa ttttaaattc atagcaatcc caagtgctgg caacatagcc
     1261 ccaattacat taaatacatg taacacatta tcattcatta cttccaacat accatctatc
     1321 gcatttggac caaaataaac aactaataat gctggtataa aactcattgc aaataacagt
     1381 atctgtggtg gtactatatt tataaatgct actctatcaa cattcccttt ttgaacctct
     1441 ctatcagccc aatgtgcaaa aaaagaattt actgtcatct ttccaatcca aagtacagtt
     1501 gcaacagttc ccaatggtac agctattgcc attgcagtac ttacatctag cttagatgct
     1561 atagctaaag cagtacctac atatcctgca aaagctgggt cccccatctg agctccccct
     1621 gctgatataa aacctagata tatcatattt atacctgctc ctataattgc tccttgaaca
     1681 gggtctccta atataattcc cgttacaaat ccagccaata gaggtctatt ccatgtaaaa
     1741 aatccaacat aagtcaacca cggactccaa gaaagataat aaaaaattgc tattaatact
     1801 gcttgaatta gtgaaatgtg catattcttc ctccctattt tcttttaaag atttacaaga
     1861 tagtcttctt tacaataatg ttcctacatc aattttcttt gcatctggta ctatttgtat
     1921 aaagcattta acatcttttg atattagctc tctaaatatt tctttttctt catctgacac
     1981 agatatattt ttataaaaac tttttctacc aagccctgct cccatacctc caacattcaa
     2041 ttcctttaaa tctaccccgc tatttactaa acctaagaca gttttagggt atttgaccaa
     2101 tactattaaa ttttcatctc cattatatga ttttaagact tcagcacctg attctacatc
     2161 atgtacttca accttaacag ttgatggagc tgccatttgt aaaacttgaa ctataaatgg
     2221 gtcctttact actaaatcat ccacgattat tatccttttt gccaatgtaa tcttacacca
     2281 agcagtaata acttgcccat gtattaatct atcatcaatt cttgttaatg ctatattact
     2341 cataattatt cctccagatt tttaatttat tttacaactt taaaacagtt ttaacatctt
     2401 tgattcctga tatcccaact tcctcacata aattcttcaa gtcttttaac ttcatagtat
     2461 ctctgtttaa aaataactct aaaagcatag gtaaatttac acctgtcaaa cattctaact
     2521 cacatacctt agcaaattta tttattataa tagcagatgt attaaatgga gttccgccat
     2581 aaaaatcaag caatactaaa accccttcat ccttatattt ctcaattcca tcttctaact
     2641 ttctactaaa ctcatctatg ctgtcaccat ggtttaatcc taaagtttct acattttcct
     2701 gtttgcctac tattaattca gcactttcta acattgcttt agccatattt ccatgtgtgg
     2761 ctataattat tcctgccata tgaatcatac ctttcttaac cttttttata tggattatta
     2821 tttagtactc taatctaatt atctatatta atcattatct taccaaagaa aatatccctt
     2881 ttgtatactt tttcaaaata agctggtact tcttctaaat ttattctatg tgttactaat
     2941 ttttcaacat tcatatcacc cttttgcata tgatacaatc cagcactcca ttcttttcct
     3001 gggaatggaa aggagtttcc aaaccaagtt ccctttacag ttaattcact tcttactatc
     3061 ttttcaaatt gctctctagt caaagctaca tccccatatg gtacacctgc atacaatact
     3121 gtacctccct ttttagctag caacagtact tgaccacatg tcagtggagt accagccgat
     3181 tcaataacaa tatctgcacc atctccatca gttaaccttt ttatttcttc tacaatattc
     3241 ttttcttttg catttataca aatatctgcc cctaactctt ttgccaagtc taacttctca
     3301 tcaaatacat ccacagctat tatttttgta gaaccaaata tttttgccca ttgtattgaa
     3361 aataatccta ttggacctgt accaagtact acaacagtat ctccaacttt agcttctgac
     3421 ctaaaaagac catgtcctgc tatacatact ggttctagcg cagcggcagt ctcataactt
     3481 atctcatctg gtatttttat taaatttctc tctttcacct ttgtatactc tgcaaaacaa
     3541 cctccaagtt ctttatttcc tattattgct acattattac atcttgaata caagcctttt
     3601 ttacattcat cacattcaaa acatggcata gctggacaaa cagcaactct atctcctatt
     3661 ttaaaactcc ttacttcttt accaacctgt gccacttctc cagaaaattc atgccctaaa
     3721 atttctccaa ccatatgtgg acctgtcttt gaatattttg atatatcaga accacatatt
     3781 ccagctactt ttactttaat tattacatca tctttttcta atatttttgg tacatccaca
     3841 tcctccactc ttgtgtctct tataccatag aatctaactg acttcactat taaccacccc
     3901 tactttttat ttgagaatat atccctattg tttatatgtt aaatatctaa agcaactttc
     3961 atgccaatat atgtaagcat tgtattcatg cattttataa aattatcatt aaatgtgtgt
     4021 caaagtgtgt caaaagtttc ttatattaaa acttatgtgt gtcaatataa atgacactaa
     4081 cattttatat tagttctctt attataagtt ttataaaatg tacttttttt gttattttta
     4141 taaaattgtt cggaaatttc ccttctattt gtgatataat attaaatata aggtatcaat
     4201 ataaattttc atgcgaatat cagaactttt ttgacactaa tgccttattc aatataataa
     4261 tttaactttt tggaggttgt ttatgaaaaa agtgtatcaa ggaaagacta aagatgtttt
     4321 tgaattagat aatggaaatt acttacttaa atttaaagac gatgtaactg gtaaagatgg
     4381 agtatttgac ccaggcgaaa atagtgtagg tctaagtata gatggaattg gtagagctaa
     4441 tttagagaca tctgttaagt tctttgaaat tctaaacaat gctggaatta aaactcatta
     4501 tgtaagtgct aatttagaag aagcaactat ggaagttcta ccagcaaaag tttttggtaa
     4561 tggattagaa gttatttgtc gttatagagc tgtaggtagt ttcttacgtc gttatggttc
     4621 atgtgttgaa gaaggtgcta aactagattg ttacgtagaa gcaactttaa aagatgatga
     4681 ccgttgtgac cctcttataa catctgaagg tttagaagct ttaaacatta tgactcaagc
     4741 tcaatttgat tcaatgaaaa gcatgactca aaaaatttct aacatagttc gtgatactat
     4801 agctgaaaaa ggtcttgagc tttatgatat taaatttgaa tttggattct acaatgatga
     4861 agtaatctta atagatgaaa tagcatctgg aaatatgcgt gtttataaag atggtgtaat
     4921 agttgaccct atggatttaa ctgctctttt attagataaa tagtatatac atataattta
     4981 caaatataat aaacttataa ataagataag ctatgaagta aagacttttt aaatgttgat
     5041 tatttttaaa cattttctcg cctttaattt catagcttat ttaaattaat atactctaat
     5101 tagtagataa tagctttaac cctacaattc ccaccacaat aaaacctata catgcaattc
     5161 ttgatatact aataggctca tttaaaatag ccatgcctac aatagctgta ccgacggtac
     5221 caattccagt ccatattgca tatgaagttc caagtggaag atgttttagt gctaatgaca
     5281 aaaaataaaa acttacaatc attccaacaa cagtaagtat acttggagtt aatttagaaa
     5341 atccatgtga attttttagt tgaaaagccc aaaacacttc aaacaaacct gcaacaaaca
     5401 aaaataacca tttcataaat tcatccctct tttcaaatat gtctcttatt tttccaataa
     5461 aataacctga gaaatattat aaaatatctc ccaggttttt gtccttccgt gttcacaaca
     5521 aaaactatgt tgtgggtttt atctcggacc agaccaatca ttaataattg cggaacccta
     5581 taaaactcta ttaattattc tattttatct ataataatac tatcaacata tataaaaaaa
     5641 gtcaatatat gggttacatc tataataaaa ataactttta tatacctttt aatattctta
     5701 ttcacttctc tccataccca tttaggtcaa tctaagaata tctaattttt atttaatatg
     5761 ttataataac ataaaaatat tgaaaggagt aatttctatg aatttctata aaattgcagt
     5821 atgtcagatg attactacag aaaataaaat tgaaaatatc aatcatgctg tagatatggt
     5881 aacagaagct gccatcaatg gagctaaaat tgtagttttg ccagaaatgt ttaactgccc
     5941 atatgaaaat aaatattttc ctaaatttgc tgaagaatat ccaggtgaaa caacaacgat
     6001 attaagtaaa ttagctgaga aacatggaat ttatctagtt tctggtagta ttcctgagtt
     6061 agaagatgga aaaatctata atacttgcta tgtatttgat aaaaatggat ctctaattgg
     6121 aaaacatcgt aaaatgcact tatttgacat tgaagttaca ggaaaagtta gttttaaaga
     6181 atcagatact cttacagctg gaaatgatgt cactgtaata gataccgaac atggaaaagt
     6241 tggtatagct atttgctatg atattcgttt ccctgagtta tcacgtttaa tggctcttaa
     6301 aggtgctgaa atcgttatct tacctgctgc atttaatatg actactggtc ccgcccattg
     6361 ggagttatct ataagaatgc gtgctttaga taatcagata ttctatgttg gtgctgcacc
     6421 tgctagaaat atgaatgctt cttatatagc ttttggaaat tcaagaattt cagacccttg
     6481 gggaagaata attgctcaag ctgatgaaaa agaatgtatt atttatgctg acattgatag
     6541 agatttaatt cctgacataa gacaacagtt accacttctt aagcacagaa gaactgattt
     6601 atatgaactt aatactttga aataaaacag aacataaccc cataaatcat aaattaagtg
     6661 ttaaaaaaat ttatggggtt ctcattaatt tgatttaaaa ttaatttcat aaaaataatg
     6721 ctaatattaa tttaattaaa taatactaat aattactaat gattatgcta attatcagca
     6781 tttactaatt taatcactat tagttatttc ttttattaaa tatctttact tttttactta
     6841 ttatgtcttc tagctttaca tttggattat ggtatttctt tctattttta gtcacatctt
     6901 tctattgaat tacttgctta aaacaccaat gcacacatgc cagataatgt tcacaattat
     6961 gtagaaatct tgctctacct tcttcaatgt tgatattatc tctcctagtt gatattatct
     7021 ttcctaaaat ttcttttaat taaaaaataa cattagttga tatatcaagt atattttaag
     7081 caactgaaaa aacaataata attgatatat caactaatta atgtagatta attcattttt
     7141 ataatttata tacttgttaa ttaatctacc ttatttaatt aaaatccttc ctttctattt
     7201 atccattttc aacttaaatt ataagatttc atcagctata tttttgcata ccaataagta
     7261 ttaaatatca aatatatatt ctattaaaat ttctaataat ttcatccttg atttatttaa
     7321 tatataaaaa tatactaact ttaatgatta agttttgaaa tataactaag aatttgataa
     7381 tttattgaga tttttatact aaaatataca tactatacaa acttaattta gaagggagca
     7441 ttcttatgaa caataaaata ctcgttgtag atgatgagga aggtataata acactcttaa
     7501 aagattactt tgaaatgaat ggttatgagg tttacactgc tcaaagtgga aaagacgcat
     7561 taaaaaaaat atccaaaaat ccagatatca ttctacttga tataaacatg cctgaaatag
     7621 atggaattga agtttgtaat agaattagag attatgtatc atgccctatt ctatttctta
     7681 cagctagaat tgaaaatact gacaagataa atggttttcg tgctggtgct gatgattata
     7741 ttgtaaaacc ttttgattta gacgaacttg gagctagagt atctgcccat ttaagacgtg
     7801 aacaaaggaa gtcaaatcaa actaaaatta aattttataa tgatttaaca atagattacg
     7861 aaaaaaggtt aatttgtata tataataatc agatttcact ttcaaaaaag gaatttgata
     7921 tagtagagct tctctctatg aatcctggac aagtatttga taaagaaaaa atatatgata
     7981 gaatctgggg atacaatagc aatggaaata gtgatgttat aatggaacac attagaaaaa
     8041 tacgaatcaa actatcaaaa catactcttg aaaattatat agaaacagtc tggggagttg
     8101 gttataaatg gataaaataa ataatatgtc attaaaaaaa gctttctttg ttcttacttt
     8161 atcttcacta attatagcat cagcacttac tactttcgca tacattttac ttaataatct
     8221 atataattct atacaagata agtatttaaa aacacctata aatacaggta ttataaccat
     8281 agttcaaaac aatgtgaacc aatttagtga ttatgataaa acattactta atataatcaa
     8341 catacttcag cttgtacttc cacttatatt ttttatagga cttttattat tagctgatat
     8401 aattttttac aaggtaaaat taaaaacacc catagaaata ctcaataaag gtgcaatgga
     8461 aatatccaac aacaatttag acttttgctt agagtataat aataatgatg aattaggtaa
     8521 tctatgtaat gcttttgaaa aaatgaggtc tgaactaaat aaaaacaaca taaagatgtg
     8581 gactatgatt aatgatagaa aacaacttaa tgctgctttt tctcatgatt taagaaatcc
     8641 cctaacagtt ctaaaaggtt attcaaacta tttaacaaaa tacataccaa caggtaagct
     8701 tagtgatgag aagattttat caaccacaca acttatgtct gagcatatta acagaattga
     8761 atactatgta gaaaatatga gtaatgctca acgattagaa gatttagttg tttcaaaatc
     8821 tatgtcgaat ataaacaagt ttatagaaaa cttagatgaa aatatatcta tcattgctaa
     8881 acaagaagga aaatctttta cacttaaaag tcaaataaat aatataaatc tattttttga
     8941 tgaaaatatc attcttagag ttgtcgaaaa tataatatcg aatgctttta gatatgctag
     9001 aaataatgta tccatactta tatatcttga acaagaactc cttacctttg taattgaaga
     9061 tgatggtata ggatttagta aggaatctct aaaattagct ttaagacctt tctatagaga
     9121 taagacttta aatgacagca atgcacactt tggtatgggt ctttatatct caaaaatatt
     9181 atgcgaaaaa catggtggct ctatttctat tgaaaataat tctactaaca gtgctaaaat
     9241 tactgctaaa ttctcaacaa gaaattaaaa tgattttgta agctttcact gttcttatat
     9301 aagctttgtt agtttagaat ttataaaatg tatttcaatt tacaaccaat atatatacta
     9361 ttttgtagaa gttgtaagag ttgcttcaat tataatattt tggcaaaagg catttgaaac
     9421 aataatagaa atatatattt aaatatgtag aatagtatga aattagaatt ttggaggtga
     9481 ttatattaaa agttttgcta ataatattac attctctcgt attgtgtttg cattgctaat
     9541 gcttagttct acattctgtt cactgccttt ctggatatgt tatttttggt gtggaattag
     9601 tgatatactt gatggtctta ttgcccgaaa gttgagacaa caaagtggaa taggtgcaaa
     9661 gttagatagt attgctgatt tcatttttgc ggttacaatt ttggttactg tcggaaaaaa
     9721 tattgctctt cccatgtatc tatggtggtg tattgttgca atagcattgt tacggttgat
     9781 tagttacagt attggttttt ttaagtatcg cacattttca tcacttcata ctttgatgaa
     9841 taaaatcact ggaatttcta tctttgcttt tccattactc tatatttgct ttggtcttga
     9901 tgttgcagga attatgatat gtatcgtggc ttttctttct tcttttgaag aaatagcaat
     9961 tatgataaaa tcaaaagaat taaatcgtga tataaaaagt atatttatgt gaaaacttag
    10021 aatttgtgac aaaaataatt tatataataa tgaggaagta aaacataaaa aattatccac
    10081 aagtttatgt gtaaaatagt tttaaagcaa tagagttgta ttataaagcc tttagtgcat
    10141 aaattacatt ttaaattaaa aatgatactg aaactgctta tcagcactgc gaattatccg
    10201 caaatagtga agacttttta gatttaagct aaaagttggg aaaaaattga gttttaaaac
    10261 ttacactctt cttatataga aaaggagagt gttttttatg attataaaag caaaacaatt
    10321 atcaaaaata tatggttcta ataacaataa agttatcgca cttaataatg taaatttaga
    10381 aataaactca ggtgaatttg tttctgtaat tggaccttct ggaagtggaa aaagcacact
    10441 tttacatatt ttaagtggat tagataatcc tacctctgga caagtgttac ttgatgataa
    10501 agatatatat aaacacactg aaaaagaact atccgcactt agaagaaaat cctttggatt
    10561 cgtctttcaa caatttaatc ttttacctgt tcttacagca tctgaaaata tttcaatgcc
    10621 tgtacttcta gataaaaaac aacctgataa aggctattta aatgaaattt catcattact
    10681 tggaattgca gatagactca atcatcttcc ccatgaactt tcaggcggtc agcaacaaag
    10741 agttgcaatt gctagagcac ttattgcaaa accagatata atatttgctg atgagcctac
    10801 aggaaacttg gacagtaaaa gtggcagtga agttatgaat cttcttataa aaacttcaaa
    10861 acagtttgga aagactttag tggtaattac tcatgatgat agaattgcaa aacttgctga
    10921 tagaaaaatt tcaattattg atggtgttct tatggaggtg aaatagaaat gaagaattac
    10981 ctttcacttt caataaaaga attaaaaagc cagaaactta tgactacatt catcattata
    11041 gcaatagtac tatcaactat tatgacaact gtggttggac agtcaattgg tatcctacaa
    11101 aatttaagaa ttgaacaagc ccgttctttt aatggtgata gacatgtatc ctttcaccaa
    11161 ctcactaaaa atcaagttga tgacataagg aaagatgata gagtttatca agctggtact
    11221 tcaataacta ttggcagtag taaaataaag gattctggta tctctgtact tgtaaaagag
    11281 tatgataaaa caggactttc taactaccca aaattaatga aattaaaatc tggacatttg
    11341 cctaaagata aaaacgaaat agccttagat gaaaacacac taaagcttat gggtataaaa
    11401 ccaagactag gagtgactat acctatgaat ttagatattt cacttttaaa tgataccata
    11461 ccaccatata attacacagc taactttaaa ttgagtggca ttttagagga tgattataca
    11521 ggatatgtaa gtggtatagt aaatggtatt gtaggtaaag gtacatcaga aaatctatta
    11581 cctaagagat atattttatc ctctttggat tttaaaataa aacagcaaga aaagtttcaa
    11641 gaaatagtaa atcaattagc taaaaaaata aatctttctc acaattcaat tcaatataat
    11701 tggatttact taaatgctct taagatacag tttgaaaaag atgaaaatag ttctaatagt
    11761 gatggtatat ctatgattat attggtatct ttatttgttg ccttattggt tttactggcc
    11821 tctggacttg taatctataa tattttaaaa atctctgtta caaagaaaat taaagagtat
    11881 ggatgtttaa gagcaatagg agctgaacca aaccagatat ataagatagt tattttacaa
    11941 atcttaattt tatgtactgt tgccatacct attggagctg taattggaat tatatcttct
    12001 aaaggcataa ctggaatggt cactaatatc ttaaatccag atatacttct agcaaatgat
    12061 aataaagaaa ttactgagct tatacataaa aatacaacag catatatgtt cccattagta
    12121 ttaagcacta atgtatcttt gattttttca tttatttcag cattaccatc agcaatatat
    12181 gcttcacatg tctctcccaa aattgctatg gttggtagta ccaccaaaat caaaagaaaa
    12241 attaaaagag aaaaaacaat aaaaaacttt gaaagacatc tagcatggct aaacttaaaa
    12301 agaaataaag gaagaactat aataactata ctatcattat ttatgagtat aacagtattc
    12361 gttgcactga gtgagttctc taatgtatta gatgtatcta ggtcagtaag taatttaaaa
    12421 gaaggagatt tttccttaac aaatgaaata tctggttttg ataaatcaac actagataaa
    12481 atagctaaaa tgaaaaacgt caatcgcact tcctttataa agtactctga atacaaacag
    12541 ggggaaatag atacagatat aaattttgaa aatagtggtg agatgttaaa aatcattgga
    12601 attgatgagc aaactttaaa agacttaatg ccttctatta cagattctat actagaagac
    12661 tttaaaaatg gttctatctg ttttataaaa aatccgattg ctatttctac accaggtgta
    12721 aaaactagac atacaaattt aaaacctaaa gatagtatca caatcaacaa aaaacaacta
    12781 gatatatata gtacagtaga taaaatgttc tttttacaag gtaatggctg gataaatggt
    12841 gttgatgtta ttgtatatga ttctgtttat aacaccttga caaataaaaa caagttcaac
    12901 cagataaata tttatgctaa agataaatca aaattagaac aaataagatt gtctattgaa
    12961 cagatttgtg aaaataatcc tggctctcat tggatatcat atattgaatc agataaacaa
    13021 cttaaagaga gttttaaaca aatagaattt ctagcatggg cagttatatt atttgtggga
    13081 ttgattggta ctttaaacat cattaacaca actcatacaa atataaatac taggactaat
    13141 gagattggag ttaagagagc tattggtatg agtaatagta gcttatataa aatgttttta
    13201 tgggaaggtg tttattatgg aatttttgct gctatatttg gttcaattgc tgggtatgcc
    13261 agtgctatta ttataaacat ggcaactata gaaaagcttg atttcactaa tataccaatt
    13321 acttcaattt tacaagctac tattatttct gtacttgcat gtattatagc tactcttatt
    13381 ccgttaagaa aagttaaaaa gatgaatata attgactgta tagatatcaa tttataacta
    13441 ttttacagat aataatataa attaaattat caatgactgt ctctattttc tttcaaatct
    13501 aactaataaa tctttttaac tataatataa gctttaaaaa aggcctgtct caaaatagag
    13561 ataagccttt tttcattgtc gaaataatga aaatatattt aacttcacaa aaaaagagtg
    13621 cctcacgaat taaaaatttc gctttgagac actccccttt aatttaaaat atatagttaa
    13681 atgctatgcc aaaatttcac acatgctcca cctgattttg aattttctat tttaacagaa
    13741 cctccaagct gttccactaa ttgtttgaca atgtaaagcc caagaccaga atgtccacct
    13801 tttgtctgcc tagcttcatc tcctcgataa aacttatcaa gagccttttt taaatcttta
    13861 gagctaaacc ctctaccaga atcacaaatc tcataagaaa tacaattttt ttcatccttt
    13921 acagtaatac taatattacc acctgatgga gtgtattgca gactgttgga tatgatatta
    13981 tcaaaaattc gtgtcaacct atccacgtcg atttgaattg gggattgtat attcccctgc
    14041 attttcaata taagttcaac ttccttttga tgagcctgta attcatagtc ttgcaccttt
    14101 tgcctcaaaa attcaggtaa atttatagga acaagattta attgtatatt tgacttttct
    14161 aagtcagacg tatattgcat cttttggaca agagcagcac ttttttctgt attttctctt
    14221 atcactgtaa gatacctatg aagtttttca ttgtcatctg tattattacc aataagtgca
    14281 tctgtatatc ccaaaataat agaaagagga gattttaaat catgtgctag agcttccacc
    14341 atttcaacac gttcctgctc catcttccac tgtgcagata aagagccttt taattcgtct
    14401 ttcatttcag aaaaggcact acaaagttta ccgagttcat tatctgaata atagtcgatt
    14461 tcaaaatcaa ggtccttttc ttttatcttc ttggacgcat caatcaatag atgtaatggt
    14521 tgattgatat tctttacaaa gcgcttagaa agccatctag taaaacccac gatatataga
    14581 aatggagaaa acagagccat tataataact gcaaatacaa atctccctct aatatttgca
    14641 aaggtgattt tcacttggta gaatagaata acagcaccct caatctttcc attatcccct
    14701 ttgattggaa cagtatggat ataaccacct ttacgaacag ttttattgat aaaattatta
    14761 aataattctt cttttgtttt aaatagtttt ttggggttag taccatataa aatattgcca
    14821 ttattatcca caacttgata tagcatatca tccccacgaa tcgttctttt taaaccttct
    14881 tcattcgatt gtgataacaa agctatgttt ttttcattga tgtatttttc aattctagga
    14941 acttgtcgct cataatagtt tggtggatag atatccttat ttaaggaatg aatatacaaa
    15001 tagagagcaa atacataagt aatcactgtg gcaactatac tggctattat aataaaaata
    15061 aaagtatgtc taaattgggt aataagggat tgatttttca tttaataacc tctctctctt
    15121 tacattttat tccacttata cccaataccc caaactgtgg aaatatattc tttttctggt
    15181 gtcacagcag aaaacttagc tcgtattttt tttactcgtt caacaacagt tgaggaatca
    15241 ccttcagaat cacaccccca tactttttca tagatttgtt ctcttgagaa aacttgtcct
    15301 gcatggagtg ctagtaattc aacaatatca tactctattt ttgttaaatc aatattctta
    15361 ccatcaattt taattgcacg ttccttcata tataagcata atttcccaaa atacaaagta
    15421 gatctcttgt tctcttcatt gatatactgt gaacgctttt ccctacgcag attagcttca
    15481 atccttgcca taagttcacg cagtccaaat ggctttgtta cataatcatc ccctccaaag
    15541 gtcaaccctt tgattttgtc ggtttctgat tgctttgcac ttaaaaatat aattgggcat
    15601 aaaacatcat ctctaattgc ctgacatacc tcaaatccat tcattttagg catcataata
    15661 tccagtataa taaggtcagg ctcctgtttt gataactcta tacctgcctg accatcataa
    15721 gctatcaaca cttcatgtcc ttttgccttc aattcatcct caagtagcat tactaggtcc
    15781 atttcatcat caataatcaa tattttactc aatataacac cacctttctc ttatgggaag
    15841 gtcagtatta aaacaatatt cgtctactaa taacttttcc ttccctccca cattttaaac
    15901 caaataacgc ctcctatcaa gaatataatc aaacctattg ctactactat aagctctata
    15961 ctagctgttt gcatcacttt agagtaaaat gcctcagttg aaatagttcc agcttcttta
    16021 ataaaataaa ttcctggaag catacctagt tttactggcc atgtccatgg aacaaatgcc
    16081 catacttttt caccaacgct agttaatcca agtattgctg ccatcaaaat tccaccgata
    16141 ctaataccaa tagatgcacc cataccccat gcaaaactca cccaaagatg aatagctaat
    16201 agtggaagtg tcccaatcac cacaagtcct gctgctgaca ggaataacca tattgttgct
    16261 ccagatggca ctgcaatact cattcctatg caaagtatca acgtagcaat aaatgtgcat
    16321 atagttaggc aaaacagaag aaaaagaaat tttcccagat ataatctaac acgagaaata
    16381 cctacacata aaaaaccatt aaaatttcca gcaagctctt cctcctgcac tataaatcct
    16441 gctaaaatac ctactccaat aggaatgatg aatacagtcc atactgtaaa aaatccttca
    16501 aaagcaaatt cttgtgtact tccagattta gttgtgagat aaaaaaccac acataatgaa
    16561 aaaataatag gcatacaaag agtaagccac tggacagctg tcctctttgc tcgaagccat
    16621 tctgatgata atagctttat catttgtcat ccctcctatt gaaccaagct gcagtaagtg
    16681 ctgttaatac tataaacaca accaaagaaa caacaatccc aataggaatc actgaagtat
    16741 tcaaaagtgg gtctccagct tctaatatag taccgttagg atgtatgttg atgattgggc
    16801 ataccattct aactgcccaa ctccaaggta ctgcaatcca aaatggtttt gtcgcagcaa
    16861 ggacaccaaa tatcatacct aaagctccaa ctcccatact taggaacata cctttccatg
    16921 tagctagcca tagctgaagt ggaagtatag caagagaaac aacccagcat acaatacttg
    16981 cccctataat ctgtccaaaa ggaactggac cagctttcaa tattaaacca gttataattg
    17041 ttacgactat taaaactagc gttgaaataa aactgtagac tgccatagct ataactttat
    17101 taatccaaag tgtcatagga gacacattgt gtgtacgtaa agcacgataa tttccagctt
    17161 ttttttcctg gaaagctacc aaagtagcaa acaatgcaaa tccaataggc agaaataaaa
    17221 atgaccacca gttaaaaatt aatgctaaaa gactttgcca cgcccaagaa gttgtttgag
    17281 ataatggatt ttgcatgagt gttgattgca ttataaatgc atatgctgca aaagacactg
    17341 ggaaaaaaac aataagttta cccataaatg ttcttttata ctttaaaagt tctgattgta
    17401 aagcattcat ctgttttgtc ctcctttaag aataacatct gtaaaaaatt cttctagatt
    17461 ttcattaggg tcaggcattc cttgaaataa tagtcgtcct ccatttataa ttcctatatt
    17521 atctacaact tgagcaacct ctgatagaat atggctagaa agaattacag ttataccttt
    17581 ttttggaaaa gaagcaatca attcacgcaa ttcttgaatg ccaaaggggt caagaccatt
    17641 ggttggttca tctagtatta acaactctgg gtcactcaaa agtgcaatag ctattcctaa
    17701 cctttgtttc atacccatag aaaattgtga agctctcttt ttacctgtat ttttcaaatt
    17761 tactatttcc aacacttcat aaattttatc tttaggtatt cccaatattt ttgtatgtac
    17821 taacaaattt tcctctgctg taaggtttcc atacaatgca ggggattcta ttaaagaacc
    17881 tatttttgca agagattctc gtttccaagg ctttctatca aaaataatac gaccatttgt
    17941 tgggcgaaga agaccaacaa gcattttaag tgttgtggac tttcctgctc catttggtcc
    18001 taaaagtcca tatatactat ttcgttcaat ttgtagagaa acattgttaa ctgccatttg
    18061 ttctccatat ctttttgata agttttttgt ttcaagaatt aaatctttca tattaatttc
    18121 tcccttcttg taatacctta aatctgttac taagagaata ctaacatgaa aaaataacaa
    18181 ttctataaca cctactaatt ttaataaaat ttaaaataaa aaatagagtt accaatttta
    18241 ttttggcaac tctatttaag tttatgtttt acagttatat tagatttaaa cttagtttca
    18301 ttatcacact aacttcaaat ttactctata atctttaaat caaacactac tttattaatc
    18361 aaacactaat ctattaattt atatttcttt agacatctaa tatagtttgc tactaaataa
    18421 taattattta tatcatattt atctaatcct ttaaaagaag ttatttcatc attaagctca
    18481 tcactacctt ctacaaaaac acaacctgtt tcaaattcca tacctacaat aatcttacag
    18541 ccactataaa tttcctcttg agtatcgtac aatttttttg catttccttc atttggaatt
    18601 gtaaatacaa taggttttaa ttctttatca ctggaaatct tttgtgaaaa aggcttgttt
    18661 aacttaatat tattgataac tacatgttta aattcctctg aagtttcttc tactattaca
    18721 tattttcgct ttaaaaactc tattatttct aaaacagact tagaatttac ttttaaaata
    18781 cttttatatt tttcatataa agatttccac tgttcaattt tttcctgtgg tatttcttgg
    18841 atatgtgtac ttattttttc ttgagatatt tttttcaatt aaactctcct ttcaatactt
    18901 aaatattctt atgaatctca catgactaaa gttacaaggt ttctacttaa tagaattttg
    18961 catacttaaa tatgtcttat taattctcta caggatatct ccgtagttcc tacgattctt
    19021 acataagtta cttattttaa attgttatta gttatattct aaaaattatt tattttatca
    19081 ctaatataat actcttaaaa actttacaaa tcaatttaaa tttgctacct tttatttata
    19141 acaacttata gtacatttct cctatgcttt tcaatatatt acttttaaaa ggaggttttc
    19201 cttatgattt taaatagaac tgagcttttc cgaggatatt ctttaaatag atttaacgag
    19261 atatgcaata tattatcagt aaataaaatt aaatataagt ataaagtgaa aaataatgct
    19321 tactctaaaa aacctttttt taatgaaata acacttggca atttaggtca aaaggaagat
    19381 ttctcttatg agtacttaat ttatgttcat aaagacgatt atgaacaggc agagtctcta
    19441 ataaattcta agttgcgata gattatttat aaaacatgac attctgttgt catgttttat
    19501 atgttattat actttcaaat atgctaatat attttcaaaa ttgtgtgctt taaaactagc
    19561 tttttatagt aatttaaagc ttaaaactaa ggagactcgt tatatgaaaa taaatataaa
    19621 atcaaagtta agtgaattta ttaaacagaa caatcttttt gatgacagca gaataatatc
    19681 ctaccttcct aatataacaa tagaaacaga caaaataaaa actataatga ttaatgaggt
    19741 tgtcccaact aacaccaatg acgattttta tagtgtagat aaagatgctg attatttaaa
    19801 aactactatt cctttatttg acagtgcagg aataaaagta tctaacataa atgatatcct
    19861 agatatgggt atctatataa ctaatgcagt aaaacttcct aaatcagaat atacaataac
    19921 tcgtgataca attaaattac atatgcctat tttagaagaa gaaattaaat tatttaaaaa
    19981 cctagaggta gtaatgttaa tgggagatgt tgcaaaaaaa tcttttaata tgattactaa
    20041 aaagcatata aaaaagaatg tcatcccttc catttcaaca tataaacttc gtaataatga
    20101 actttattat gataatttaa gagtatttcc atcatatatt atgactggtg gaaacatact
    20161 gattgaaaaa tcaaaatttg aaatggcatc agaagatata aaaaaaatgt tcgagattat
    20221 aaacggttga tattacaaaa taataaaaac taatataaaa taaaaagtgc ctcaaaaact
    20281 tctatttatg aggcactttt attttatatt agtgtaacta tatactatta acataattta
    20341 ttatttatat tgttcttttt aatctctatt ccatttagtc taggtaacat tactctttac
    20401 aagattactt tatatttctt ttatatctct aacgttttta tttaataaaa caattattaa
    20461 tacaagtcaa atatatctat ttatctaaaa atatatcttt tacagtaata tctggatggt
    20521 gatacttctt cctattcgtt aaaaaagatt tttttacatt aatagcctct tttggacacc
    20581 agtgaaaaca agctaggcat ctttcacact cattacccca ctttggcttt ttatcaacta
    20641 tacttatatt ctctacagga caaacccttt tacatgtccc acatccatta catttatttt
    20701 ctgcaaaaaa tttagtagtt gcaatttgca tattcttacc tactaaacga agtacaacac
    20761 tatctatatg tgactttaaa ttgttttttc cttctatatt tccaatctcc aagttattga
    20821 tacattttgc aatctcagct accctattag tctgattttt caatctttct tcttcaacat
    20881 ctggaggtgt tatcaaagca tttccaggca tattgattaa aaaaccagca gataattttt
    20941 tccccctttt tttaagtaac ttatctatag taaataaact atgtccagct accccattac
    21001 aagtggcaat ggcatatata tgagtattaa tattaaaatt taatttctct acaaaagact
    21061 ttactatatc aggaacatca gcaaaataaa caggaaaaac aattaccaat atatcttcat
    21121 ttatgtctat attattttct tttctatgta tagctaaggg tataacttct ttacttccat
    21181 ttaacgtttc ttttaaaata tttgaaacta ctagcgaatt tcctgttcta gaaaaataat
    21241 aaatcttact attcattctt atccctcttt ctatatttct acatcatcaa tagttaaaaa
    21301 gtctcttaaa ataggattta tatttacttt ccaattctat ccaaaatatc agtaaacaaa
    21361 ggcaattctt catcagagat agatttaaat gtctctgtcg catatatact tgcaatttca
    21421 tttaatggtt cttctaattc tctacctaaa tctgttagga atatttgaaa cttacgtcta
    21481 tctttaacat ctactttacg gacaattaat cccttatttt tcataacatc taagattctt
    21541 gtcgtattag atttatcctt acatgatttt tcacataaat ctatctgaga aattccatct
    21601 tgctcccata gaaaccttaa taacgcataa tggtcagttg ttatatcata tccattttgt
    21661 ttaaacatct tttttaaatc atcttttact tttaacgaag tacttactaa cttagttgta
    21721 gcttcatata gtttctcaaa atctttcatt ttacctccat ttaaataatc ccttgctcct
    21781 cccatctatc aattattccc ttatattgct caatatcttt aaaagccatt ggctttaaaa
    21841 cagcatttat agcaataaaa ttatagattt gagaaagcac aggtggattt ttcttttcct
    21901 ctatgcaata aataaatttt ttagatacct tttgtatctt tgattctact ttttcagtta
    21961 taggattttg attaaatcca gtttttatag ataaactacc acaaacataa cctcccgaat
    22021 ctaagaccat ggattttata aaagaaattg cttttgaacc acgtgcattt tcatatgtag
    22081 taactgctat acatggctta cgatacaata atctttcaag catcatatgt gctctatctg
    22141 taaacacctt gaaaagtcca gttacactac ttccataagt tgggctacca aatataacac
    22201 catcactctt agtaattata tcatgaatat actctacttt atcattttga ttgatacact
    22261 tgcccatttt ataacaattt aaacaaccaa tacaatatga tggattgacc tcacttaaat
    22321 caaaataatt aatttttaca tctggtatta atctttctat atctttatac aagtaagtca
    22381 aaacttttga tgtagctcca ttttttctag ggcttccatt tataactgta attatcattt
    22441 ctatatctcc tttttagttg ttatatcaac aataagtata tcaactatat ttttagctgt
    22501 caatataaac tatttattta aagctatact tacacagctt aaataaaagt tttatttaac
    22561 tacatgtgct tacttaatca actataaatg aattattttt aataattgac aaactaaatt
    22621 aatgataata tactttatgt attacaaatg taagtagaag gaggtatagt atgaaaaagt
    22681 taccacatat ttcagaagca gaatatcaag ttatgaaaat tatttggaaa tatgctccta
    22741 tcagcactac tgaagtaatt gaaaagttgg tagaaacaag tacatggagt cctaaaacaa
    22801 ttcaaacaat gttattgaga ttagttaaaa aaggagcttt aacatatgaa aaaaatagca
    22861 gagtattcgt ttatactcca cttgttaaag aagaagaata cgtagctaca gaaagtagtt
    22921 cttttttaaa tcgtttttat aatggtactc ttaattctat ggtactaaac tttttagaaa
    22981 atgataaact atctgaagat gatattgagg aactgagaga aatcttaaat aaaaggacga
    23041 ctaaggggga taaataaata tgtatgcccc attctttata cgatttttac tcagtacatt
    23101 aaccttatca atattaattg ttgtaatttt acttgccaaa aaagtattta aaaaacatat
    23161 ttctgcaaag taccaataca atattggatt tatattgctt ataatgttaa taattccatt
    23221 tgtccctctt aaatatatta atcttggaaa tgtatttaac tatttatata cttttaatca
    23281 acttggaagc agtactaata ggacttctat gataaaaaat agtccaaatt ctataattaa
    23341 taactcaaat gcattaaacg atttttcagt atccctaaac caagttaatt ttgatagttt
    23401 aaatatttta ttactaatat catggataat tggaatttta atcatgatag ctattactat
    23461 tcattgcaac attaaaataa aaaatatgaa aaaatcaata caaattttaa gagatgatga
    23521 gatagtattt atatttgaaa agtgtaaaaa agatattggt ataaataagg attttatact
    23581 atgcaaatca cctattataa atacacctat tacatttgga tactttaaac cacacattat
    23641 attaccagat aagtctatat ctaaattatc tttaaaagat ataaaatata tcttacttca
    23701 tgaattacaa cattttaaaa ataaagatat actgataaat tatataatgt gctttcttca
    23761 aatattatat tggtttaatc ctcttgtatg gtatgcattt aaagaaatgc gtatagaccg
    23821 tgaaattgca tgtgatattt cagttttaaa aaagcttaat aaagatagtc atatagaata
    23881 tggacaaact ctaataaact ttgtggataa tatttcaaga ccatcaaatc ttacacttac
    23941 atcagatatt ggtgggtcaa aaaaacaaat aaaaaagcga ctattgaaga taatggattt
    24001 tcataatgaa tcaaatacgt taaaattcaa aagcatttta atttttacat tgatagcttt
    24061 aattgtattt ggaaatattc ccaaactatc tattatggca gatatcaacg aaaaatatag
    24121 acctacaaat gaacaaactg tgtacgagga cttaagtcag tattttaaag cttttgatgg
    24181 aagttttgtt atgtatgatt taaaatccaa gcaatatcat atttacaata aagaaaaaag
    24241 taaaacaaga atttctccaa attctactta taagatatat agtgccttat tgggattgga
    24301 aaatgggata ataacaagaa ataattcaca tatcccttgg gatggaaagc atcattctaa
    24361 tagttcttgg aatgaagacc aagacttatt ttctgctatg gaaaactccg taaactggta
    24421 ctttcagact ctagataaaa aaacagggct aaaaaacata caaacttatc ttaagcaaat
    24481 tggatatggc aattatgatg tttcaggtgg tatctcaaac ttttggctag aatcttcatt
    24541 aaaaatatca cctattgaac aggtagaatt acttgaaagt ttttatacaa ataagtttaa
    24601 atttgaagat aaaaatatag aaacagtaaa agattcattg ttaatatcaa aaaaggatgg
    24661 ggtatcactt tttggtaaaa caggcactgc taatataaat ggaaaagatg taaatggttg
    24721 gtttataggt tatgtggaaa aaaatgaaaa tacttatttc tttgctacaa atattcaaag
    24781 caaagattat tctaatggta gttcagcatc taagataaca ttatccatat taaatgacaa
    24841 aaaaatctat aatccttaat atatttactg tacattctaa aaaattcaca taattttcat
    24901 attaattatc gattaaattc atatacaagg cttattatat aaacatagaa gatagtaaaa
    24961 ctagcttaaa aacataatat aataccctat acaaatagtg gcaactctcc ctcacatcct
    25021 caattgttgc cactatttaa ttttttgtat gaagttaaat atattttcat catttcaaca
    25081 atttgggtgc aatacaatct ctattttgaa acaacctttt taattgtttt agagtttatg
    25141 aattatttct catactttaa aaagattgaa ttactcttga taatcttctt ttgtagtcat
    25201 tacatatcac ctactactca acacatattc tttgacctat ttttacatcc ttgcttatat
    25261 ccaaaatatt taccttctta ccatctggaa acaataccat tgttaaagta gactttccta
    25321 attcgtgtat tctctttaaa tcaacattaa caagaacatc tccctgttta accatatctc
    25381 cttgtttaac agcaacatca aatccatctc catttaatgc aactgtatca attccaacat
    25441 gaattaatac ttctccatta gttcctttaa tcccaaatgc atgtccactt gaaaacactg
    25501 tttctaattt acctgaaata ggagaaacaa tttttccatc tataatatca atagcaaaac
    25561 catcacctaa cattttttta gaaaatgttt catctggtac attttctaat gcaacaattt
    25621 tccccttagc tggagacaca aagttttcat tattttcatt aaacactaat tcttcgtctt
    25681 catcttcatt tatagcttct ttaggcactc caaataaaca tgttacaata aagcagaatg
    25741 caaccacaaa tattgatact aataagtatg tgattaaatt atatccatca tagatataca
    25801 ttaaataaga aggtaaaact gctaatccat atgaattaga ttgaatatgt aaaattgata
    25861 atattgctgc tcctaaacct gaagatgcac acataataat caaaggcttt aaattatatc
    25921 gaagctgaat cccaaataaa acaggctcac ttataccaaa aagttgagat agcattgctc
    25981 caaccgcagt ttgtttaact tgattatttt tagatttttt cataaatgct agacatgttc
    26041 caatattcgc aaatccatac attgcacaaa gagtaataag ggcattaaat cctgtatttg
    26101 ctaatagtga tgtttcaatc attacataag tatgatgtaa tccagtaata acagctaatg
    26161 gatatgtaaa tccaataata aatcctccaa ttcctaaagg caaatcaatc aataagctga
    26221 tgatatcaac catttttaat tctattgtat gcattatagg gcctacacct aacaaaataa
    26281 ctaacattgt tattagcata acaaaaaatg gtgtgaaaat aaggtctaat acattaggca
    26341 tatgtttacg gaaccatttt tcaagattag ctccaataaa tgctgtaaca atagctgtta
    26401 aaacacttcc ttgacaacct acaataggaa taaatccaaa tgccataatt gcttcaattt
    26461 catttgatgg gtcagcaaca gaatatgcat taggaagtat tggggaaact aacataagtc
    26521 caataacaag tccaataaca ggtgttcctc caaatacttt aaatgctgac catacaataa
    26581 ttgctggtaa aaaagcaaat gctgtttctg taagaaccga aacaagtgtc tgaatataca
    26641 atggaatatt tgcagaagac attccaaata atccaagtac attatcatta aacaaacaac
    26701 cctttaatcc caagaataat cctgttgctg caataactgg aataatagga acaaatatat
    26761 ctgctagagt tctcataact ttcttaaatc cagtttcatt atttttgact aattcatctt
    26821 gttctttttt tgataaagtt tttaatccca ttttttcaac ttctgcataa actttattaa
    26881 ctattcctgt tcctaaaata atttgatact gtccagaagt aaagaaaacc cctttaacct
    26941 catcaacttt ttcaactttc ttatcattaa taatttctct atctttaacc atcactctta
    27001 atcttgtggc acaatgtgta atagaaataa tattatcttc accaataatt ttaataagct
    27061 catttgctat tttattatat ttattcattt ttctacctca ctttcaataa tactgcatga
    27121 aatgctttca aacgcactgt tttatttaat agatttatat catctaaatt ttggaataca
    27181 atatcatatt tttcttctac tcttatttct acaggtttat cagaaaaatt ataataacaa
    27241 tcaataacta ccaaatctaa ttgccttcta tacgcaataa tatcatcact ttctatatca
    27301 ataggttcta ttgaaccata aatcaaacaa tcagaatact cactatcttg tctcaacttt
    27361 atcatctttt tataaaattc taaaatactc tctgaattgt taatctgact ctgtgcatta
    27421 atatctttat aattttcaat aacctttaac catggtgttg tatctgaaaa acctgcattt
    27481 tctttatctg cccatggaaa tggcgttctt gcattatctc ggcttcttaa attcacaaat
    27541 tctaacgctt cttcttctga gtaaccttca tctattgaac gatagtattg gtcaatgcta
    27601 gataaatcat taaaatcatt tatggtatct cttttaaaat ttgtcattcc taattcctgt
    27661 ccctgataaa taaatggggt tcctcttaaa aagaaataca ttgctcccaa catttttact
    27721 gcatcatcat tcctttcgta ttgcaaaaga tactttgttg tagctcttgg ttggtcatga
    27781 ttttcaataa aattagctgc ccatccatgt tcctgaacat acatttgact atctaaaatg
    27841 cattttctta aatctggaat tgtccatgaa attcttttaa accactcact accagaagca
    27901 acatctaagt cagcatgttt aaagtcaaag accattgaaa agaaaccatc ttctccaata
    27961 aaatcaccta gttggtcata gctaatacct gctgcttcag caacagtcat acaatcatat
    28021 tttttaaacg tattttcttt taattcataa agcatttttt ctattccagg ctgatttcta
    28081 actgtttttg tacatttaac aagaccatca acaccatcac tttctaaact ttgaaaactt
    28141 aaattctttt tgataaatgt aatagcatca actctaaatc ctgccactcc catttgagac
    28201 caggtattaa tcatttggta aagttcactt cttaatattg gattttccca attaaggtca
    28261 ggttgttttt taccaaaaga atgaaaataa tattcgtctc tattctctac cttttcccaa
    28321 acacttccac caaaaacaga cctccagtta tttggtaaat cgtttccttt tttaaaaata
    28381 taataatcat gataaggact ttctggattt tttaatgctt cttgaaacca aggatgttca
    28441 tcacttgtat gattaagaac taaatctaat ataattttga ttcctctatc tttactttct
    28501 ttaattaact cttttaaatc ttccatactt ccaaattcac ttgcaatatc caaataatca
    28561 ctaatatcat acccattatc gtccataggt gatttaaaaa ttggacataa ccacaatgat
    28621 gtaataccta aatcttttaa ataatctaaa cgagaaataa ttccctgtaa atctccaatt
    28681 ccatcattat tactatcttg aaagcttctt ggataaattt gataaacgat ttctttttgc
    28741 caccatttct tttccataaa ttactccttt ttatatgata tttcttcttt ttaattcttt
    28801 ataaattcca ttatcgaata tgtcctcaca tatagatgtc gctatatctt taagttgttg
    28861 atgactattt ttcattgcaa ttgtaacgtc tgatgcttga aacatgacaa tgtcattttg
    28921 accatcacca aaacatatgg tttctttttg agttactcct aatctttctt gtaatctctt
    28981 aattgctttg cccttatgaa aatctttttg aataatttca taatactgac tagaaatatc
    29041 tctctgtgct aattccattt tatcttgtag tatatctttc acttcgtcaa ataccttttc
    29101 atttgaccat aaacaaattt tatgtatatc ttgtgactta tactcttcaa tgttattttc
    29161 atatgttatt ttttcttgga tatgttgttt atttatacaa gaattagttc ctttcaactg
    29221 attcattgtt tcaaatattt ctttggcttt ttgattcatg aaaacttttt cctgactctc
    29281 aatcgaaaaa gcaacttctc tcttttttaa taaacaaaca acttccttta tcaatctttg
    29341 attaaaagat tgattataaa gtaattcacc atgatattga atgtaattac ctcctcctgc
    29401 aatatatcca tcaactccta atgataaaac atcatcttgt attgtaccca tacttcttcc
    29461 agtacaaata acaacactgc aatgattctt ttgacataaa cgtatagcat gctttgcaga
    29521 ttctgggatt ccatatacct catctctaag cgtaccatct atatcaagta ttaataattt
    29581 gtacaatttc atcttccttt cttactatca aaatcataat agcattcaaa aaaaaagata
    29641 tcaatatttt gatatctttt aaaaaatatg ttcattttta gcacaaattt tcattttcgg
    29701 ggaatatgtt cactttctaa atacatcttg tatttaatat aaagcagttc aattaaaata
    29761 aaataaggtg ttgttacatc gtagtccagt tgtttatcta cagaaataga tatagattga
    29821 atatacaggt tttcatcaca taatcttgct aaaggattac ttatcatttt tgtaatagaa
    29881 accatataaa ttcctttcat tctcatttct ttagcaaaat caataattgt agatgcatct
    29941 ccattcaatg aaataaagaa aatcatatca tctgttttta taaaatgatt aagtgcctga
    30001 atcatatcat aaccataaac atcatatata attttccctg ttggtaagaa aatccttttc
    30061 atctctttag caactctttc ctgagaataa ccttctccaa agacgattat acgatttgcc
    30121 tttttcattc tttcaaacat aatcgaacaa tccttcttct ctatatcatc tatcacctta
    30181 ttataacaat ccattaattg gtgtttactt tgatttttat attctacttc tgtttcattt
    30241 aagcgtataa taactcttaa ttcactatat ccaggtaatt gtagtttttg agcaaaacga
    30301 gaaagtgcac ttgtagatat atggtatttg tctgcaaatt catctataga aagtttaata
    30361 caatcttctt tatgattaag aatacactca cagatatact tatcatttgc tgtaaatgaa
    30421 ttataatatt tattgaaaag tccttcaatt ttcattcttt tctccttcta tactttatgt
    30481 aattcatatg aagcaaatct aatagagcat aaaatgctcc tacgacttca taagatatag
    30541 cttgtaatgt atcaagtttt tgagtttcaa catacagatt atactcacaa agtgttgcaa
    30601 ttgtattatt atcaagccta gttaaagaaa tcgtatgtat atgattgttg ataaattttg
    30661 caatttcaat tcctgctttt gtttctccag acaaagaaat gataataaat aaatcacttt
    30721 tttgaaatga ttctctcata aattcaattt cacctatatc aaataagtca ataacacatt
    30781 tacctactga aagaaatatt ctctttattt cttgagctaa acttttctgt tcattacctg
    30841 tcccataaat ataaattgtt tctgcatcat atattatttt acaaatatct tgaaatgata
    30901 ttttttgtaa ttcattcatt aatagtcgat aattctcgca aacatcatga aaattattat
    30961 cattattaac aaattctagt tgattatttt taagtaaata ctttaaatca gagaatgaat
    31021 ctaatccaat ttttctacaa agccttaata aagtagctct agaaacatta cattcatttg
    31081 caattttttc acacgaaaaa ttacggtatt ctctttgaca aatcaatatt tgtttaataa
    31141 taattttatc attttcattt aaattatcat aattttggtt aactaacgat tctaatctca
    31201 ttttttccac tccctaaata ttattttaat atacattagt tgctttttct agggaagagt
    31261 tttaaataat aaggataaaa taatcatttg attttatttt tattaaaata aaaataacct
    31321 gctaaaagca ggcaccaaaa agtacttatc ctttcgaaca tgtactttag atattgcttt
    31381 cttcagaagc ttcatctctt catactctaa aatagagttt tttctaactc aaaagtattt
    31441 tccatggtag aaattacttt aattcatctg ccatttattt tttatcttat ttaataatta
    31501 ctattacttg aatatttact tctttaagta aatttcatag ttaacaaagc taaaactatt
    31561 attatcgatg ttaaaataca aaattgtaag tattgttata aatatgctta cagctacaaa
    31621 tatacatgat atattaaaaa gaagctgtaa attattatca tacatacaag caactatgcc
    31681 tctattaatc catgttaatt ttgattattt aatacaagga gttccatgag acatacatat
    31741 ccattcatat tttaaattat ccaattctct tatagatttc atcatctttt tataatccca
    31801 attccatgga ttaggataag gaactatatt tccattctta tttttgacta aatcacctgc
    31861 aaataataca tcttcaaaaa tcatgcagac atgccctgga gtatgaccag gagtatggat
    31921 aatttttata ttcccaatct gcatattctc tccataaggt tcaacatcct taatgagcct
    31981 tctggaaatt gcctttccaa taaacttctt aaacccaggt ctatccttct ctcctataat
    32041 aaaaggtata tcctctacat gagcccatac ttttgctcct gttttttctt tcaataattt
    32101 aatattagat atatggtcaa catcatgatg agttaataaa atatgcttaa tatctgtaag
    32161 tttaatgcca agtgttttta attctttaat tatatttttc cccataaaag gaagacctgt
    32221 gtctataaga ataatttctt tatcaaacac aataaaacaa tttgagccac gagtactatc
    32281 taacattaat acattttctt ttatcttcat aaataaattc cccttatttg gtattttacc
    32341 tatataatta attaataaag ttataaatag ttataatact tgatattaat tttatttttt
    32401 attaaagtat actataggta tacaagtatt atatttaaat aagtatacca tcagtatact
    32461 tttttatcaa tagaaaggaa taatttatat gtcagaatta tcaaaaagag ataaagaaaa
    32521 aatacaaaga gaaaatgaga ttattgataa ggcagaaaaa ttattttgtc ttaatggatt
    32581 tgataataca actatgaatg aattagcaaa agaagttgaa tatactaaac gcaccatata
    32641 caagtacttt tcatgtaaag aagatttatt ctttgctgtt gtcttaagag gatataaaag
    32701 actttgggat aatgttaaaa tagaaagtgc aaaaggcaaa acagggtttg aaaaaataaa
    32761 actttcatac tttgcttttc ataaatttta ctctgtagaa ccttctctat tatgccttat
    32821 gggaatgatt ggtattgtaa actctgaaaa atcggatact gatatgctgt ttaaagaaaa
    32881 gtttttttct tttaataaat ttatgtttga tgaaatacaa ggaatgtttg aaattggaaa
    32941 aaatgataga agtattaggc atgatattga aatacctact cttatgtatt catcaatatt
    33001 tacacttaca ggatttttta atttactatc tgtaacagga aaatcatacc tgaacaactt
    33061 taatatagat gaggaaaaat ttattgaaac aactcttgct cttttaatag attcaattaa
    33121 agcataaacc taagtttata aattaaagtt tatatactta aatgataatt ttttctatct
    33181 ctaatataaa aaatattaaa cataaaacta ataacttagt taatggaata actaaattac
    33241 tgaaaggatt aaaagtaaat ggctaaaata cttcttttag aagatgatga tacaattaca
    33301 tttggaataa aaacttccct tgaaaagaaa aatcacactg tatgttgtta taatacgatt
    33361 gctgaagcta aaaaaaattt tgataaaact attgatttaa ttctgcttga tttaaatcta
    33421 cctgatggta ttggatacga gttttgccaa tatgttaaaa gtatagaaga tactccagtg
    33481 atatttttga cagtccgtga tgatgaaaaa gacattatac gtggattaga tatgggtgca
    33541 gatgactatg tggttaaacc gtttttgctc tcagtacttc aatccagaat taatgcagtt
    33601 cttagaagaa ctcattcaaa tactaacaat actattacat gtgaaaatat aagcttgaat
    33661 aaggttgaag tcaaagcata tttagataat gttgaagtac ctttgacagc aggagaatat
    33721 aaacttcttc taagtcttat ggaaaataaa aatagagcta tgactcgtac aaagttacta
    33781 gaaatgctct gggatgtaga tggtaatttc gtaaatgata acactcttac tgttacaata
    33841 aaacgtctta gagaaaaatt aaaaaatcca ccttgtataa aaacattaag aggcatagga
    33901 tatagaatgg aggacaacta gtgaaaactc caagaaatat caacagtaca gttgttttta
    33961 taatattctg cttaattgta acttttttat tgagtgtaat tctaacaact ataacttctt
    34021 ttaatgaata caatgtactg tctaaggctc ttggtgcatc atatgagtac aatcctaagt
    34081 ctacagaaag tatactaaaa tcactgaaaa attctagtga taaggatttt aaaacaggaa
    34141 atgaaatttt atcaaaacat ggatattcta aaagtacatt ttggagtaaa aacttttttt
    34201 attttctagt gatatcgttt ggtataattt caacaatggc tacagttata tatataatca
    34261 aacatagaac aaataagcaa aaactgagta gaataaacaa tcttactcaa tacttagaag
    34321 aagtgaattt aggaaaagag tctgtacttt tacgatgtga agatgaattt tctcaccttg
    34381 aagatgagat atataaaaca gttggggaac ttcgttgttc aaaagaattt gctttaaaag
    34441 aaagacaaac tctttcagat aaccttgcag atattgctca tcaacttaag actccaatta
    34501 cttctatgtc acttatggca caattacttt cagaaaattg tccagatgaa gaaatagatt
    34561 atattaacag acttacaaat caaatctcaa gacttgagag actagtttca tctttactta
    34621 cattatcaaa attggatgca agtactttaa tatttgaaag caaacttata gatgtacatt
    34681 ctcttcttac ttatgcaatt gagcctatag aaggttcttt aagagaaaaa catcagacat
    34741 ttactatcga ggcttctcct tcggtagaat ttgaaatcga tattaattgg actttagaag
    34801 ctcttttaaa tattcttaaa aattgtagtg agcatataga agatggtgga tatatagttg
    34861 cttattatag tcaaaatcct ctatatgttg agattatcat agaagataat ggtaaggggt
    34921 ttgctcagga agaacttcca tatattttta atagatttta tcgtggtaaa aatgctagta
    34981 aggacagtat tggtataggg cttgctctat caaagtctat tatagaacgt caaaatggta
    35041 ctatacatgc agaaaattgc cataatggtg gtgcaagatt cataattaaa ttttacacat
    35101 aaaatgctgg attataggta aaatacctat aatccagcta tatctatatt ctatgttatc
    35161 tattgtttta gtaatatact tctatttaca tttaaggttt tattaaacaa acaacttaac
    35221 tatccctata cttgtaagta gtcttaaatc gaaaccttta aataagttca aatagatttt
    35281 gtttatattg tttcattttt tatagattct actatatttt cattcttcaa ctgcttgtat
    35341 cctgtcatat atgatgctat tacaataaaa agtatcaata tagtaaaacc tattattgta
    35401 gatataggtg caaatggtaa atactctata aaatatattt catttatacg tagaaaagca
    35461 tacactattc ctatttgcac aggaatacta agtagtaatg gtgtaattcc taagaataaa
    35521 ccttccaaaa taagcatctt ttttatgcct tctggagata atccaacaga acgcaacata
    35581 gcaaactctt gtcgtctact tctaatattt cctgacactg tagcaagtac atttgataat
    35641 ccaatcatag ccaataaacc tgtaataaag cctactatta aattcatggt ctttattcca
    35701 ctagcctttt gtttttcact ttctaaaaca tcctcaatac tataatctcc tgaaccatag
    35761 tctttattat aaatggactc taatttttct cttactctag gaatgtcctc acgattattt
    35821 actttaaata ctcctatcag cctatttgaa cgtaacctac ttacttcatc ataattttta
    35881 gatatttcct gcaccataga cattggaact atttgcatta atgtatactt tgaactagta
    35941 tctactattt taggaagtgt gcttgtaata gctcccactt tcatgttgta agtataatcc
    36001 cctttatctt cgtcatatac tttttcattt aatttaatgt tatctcctat tgaaagattt
    36061 aaataatcta tatatacttt atttctacgt gtactacgat taatatcttc ctccttatta
    36121 tatacaattg aggttggatt ttttgtatca taaaataact ttgggtctac agaaatttgc
    36181 ctacaatatt ctgtaaaact cttatcatca agcccaatta tatttgaaat tatacgaaac
    36241 ttgccatcac gttctatagg agagtacttt ttagatgaag ctatattttt aaatcctcca
    36301 tttttcgcaa gttcttttga agcatctttt tcagtcaacc aagtggaagc agacattttt
    36361 tgataatata gtgaactttt tacaccttct gtattatcta atttttcaat gaaagcagac
    36421 tctacaggtt cactattttc caaataaact gctatatctc tttggtcctt ataattatca
    36481 cttccataaa cagcttttgc tccttcttga tttgcaatta tatgcaaaaa acatgtaagt
    36541 aataaaaaag ataatgttaa agatattgtt gcagtacgat aagatttttt acgagcacgt
    36601 agtgcgtttg atgcaagttc tccttctatt ccaaatatct ttcctaatga atatttatgc
    36661 gactttttga ttttaacact atctccttgt cgtattgctt ctataggaga tatctttgat
    36721 acttttcgtg ctggtataag tgcagaaatc cagactgtta ctattgtaag taaaactgct
    36781 ggcagaaaag caggaatacc ataagtaaat accacttctg gaacatcagt atgataatta
    36841 actgaattaa tataaactat aagcctatta cacaataacc atcctaaaaa taaacctatt
    36901 ggtaatggta taattgtcag taaaaagcct tcaaacacta cagacctttt aatttgtttt
    36961 ggtgatgcac caacactaga taatatccct aactgagtaa gtctagcatt tgcagacagt
    37021 gaaaacgcgt tgtaaatcac cattacaaac acggctactg taaaaattgc tattgtaaga
    37081 tacataatag gagttgaaaa ttttgatata ctactcatag atgctttctg ttctggtgaa
    37141 aagactaaca actttaaaag ataattacta ttgtatttaa gattgtattt tccatattca
    37201 ttagtcttcc accccaatga tttagcaagt tttggaagtt ccttatacgt gtctcttata
    37261 tttttaaatc gcaagtacac agttatacta tcattaggtt ttatacttgt tttatcaaga
    37321 tagccaagag ctgtatatgc aggtattact gatgaagtag aaacatctac ctttcctact
    37381 attgtcaatg tagtctctga aattttttta aaactttccc ctttcgattt tggggctatg
    37441 ggttcaagag gctttccatt taggattcta tctcctattg ggagagtaat tttatcacca
    37501 atttttacac ttggattatt ctcaaaatat tgttttgata atgcaatttc attagcatta
    37561 tttggtcgac gaccctctat tatagtatcc ttttctggca tagaatccca atactctaat
    37621 gtagcatttc tataaattat ataatctctt ttctcatcat taattttgcc tacataccat
    37681 tgtcctttta ccattacatc atcaactgaa gaaaaatttt caattaatgg taagtcactt
    37741 ccataagtat agtcaaacaa ttcaccatgc cagttacctt ctttctcaat tgaaagtctt
    37801 ataaaatctg tccacatggt atacaacagt ccacacaaag aagacatcat ggttgtagta
    37861 agtaatatag ctaacattat agctatacta ctacgtttat tgcgtcgtac aaagtctaag
    37921 gtgtattctt gaagaatatt catttcttca ccaccttttc agagacaatc actccatctt
    37981 ccatagttac aatacgattt gcctctagtg ctattttctc atcatgagta ataagaagta
    38041 ttgtctgatt aaatcgttta tttgataagt ttaacaagtc tacaatttct tctgaatttt
    38101 ttctatcgag attaccagtt ggctcatctg ctaataaaat agctggtcta tagattaaac
    38161 ttctagctat agatactctt tgttgttgtc cacctgaaag ttgacttgga agatggttta
    38221 atctatcaga taatcccaat atagatacaa tctcagagaa tctatcctca tccacctttc
    38281 ttttatcaag taacataggt aataatatat tttttctaac atcaagagta ggtataagat
    38341 tataaaattg ataaataaga cctacttttc tacgtctaaa aactgcaaga gcttcttcct
    38401 ttaaacttga tatttctgta tcttcaacat aaatctttcc agatgtaggt ctatctactc
    38461 ccccaagcag atgtaacaat gtagatttgc cagaaccaga tgctcctaca atggatacaa
    38521 aatcaccttt ttgaactgat aaatttacat tattaagggc tgtcactctg gtttgatttg
    38581 aaccatatat ttttgtgaga ttttcacatt ttaatatttc catatacaat catctccttt
    38641 atggttaaat tttagcaacc taaaatgaca ttatagtgac atgaatacaa atataaatta
    38701 ctattaaaaa tattgtttag tttttgcaca ttatttaaaa ttataatata aaacaaaaac
    38761 tatgcaatat attttattta tacttttaat atattacata gtctttaaaa ggtattaact
    38821 ttaaatctat aggtattcaa tttaataatc aatagcaagt attttatgta ctaaaggagt
    38881 tttgctctat atagactcaa tttagtaaaa ttatttaata aatattacag actataggta
    38941 aataatattt acaaataaaa ttaagtttat tcccttacac tataatattt cttaattata
    39001 ttaattgcaa tttcctttac ctttggccct gtaatttctt tattggaatc atctgattta
    39061 atagcaaaat aataggtgtc accttcacgc tctagcatac caacaaacca tgcatccaca
    39121 cgtttatttt tttcatcaaa tcctgttcca gtttttccat atacatttat gtttttatca
    39181 tttacatcta ttttcataat atctcttaaa atattaatat gctctttttt aaagtttgta
    39241 tatccctcaa atatttttgc cattgtttgc acttgttctt ttggagatat ttgtaatgaa
    39301 gattctaacc aaaatccatt taaatgtccc tttccatttt ttaaatctcc ttcccattcg
    39361 ctaatatcgc aattcccata ctttaaatca tctaaaatgt tttggacaga tttagcatca
    39421 actttattta tcaatttttt gtagtaccaa acacaagact ccttaaatgc ctcttctaaa
    39481 ctaagatttt tattccaatt tttatttgga tactctgtac catcatatcc cataactgat
    39541 tcttttgagt ttattacccc tttttctaaa ccaattaaag ttgaaactat tttaaaagta
    39601 gaacatggtg accttcttgt ttcaattaat tctttgttat atatattata ttctttattt
    39661 ttagtattat aaaaaatagc tcctccacta ataccttcaa aacaatcact atagtcaacc
    39721 atattaattt tttctttttt gtttttatta ttgttttcaa ttttggattt atttaattca
    39781 gacttattta attcagattt tatataattc ttatcagttt tttgatttat atcgttatgt
    39841 tttttcccta cataatacat taccataact acaccaacca ataagatagc tatccaaata
    39901 aaattctttt ttcttttcat aatttatatc atctcccata tttaaattta taacctacta
    39961 ttaaaatagt agacattatt tgtaatatac tccaatctag gttctactta taagaaacaa
    40021 gactaaatga atagctgtat ctcttatatt ttcttcacct agtacaatta tgttgattaa
    40081 acctattgcg aagataatta ggtaactatt aataacatcc tgtcctcctt ttaatttgtg
    40141 atataataat tgattccaca tttaaaactt actattgtaa tatttaaata ttacaatagt
    40201 aggttttaaa tgtcaagtta gtttgggaaa gttattttaa ttgtataatt gttattacat
    40261 ttataaaata tggcatgttt aaaattattt tgctattggg aggattaaga taagcagtat
    40321 tataaaagct ataaattata aaatttaata tataatttat agcttttact tttacaaata
    40381 ttgtttttat tgatttatta atgaatttta tttacaggtt atatttatat aagtaaacac
    40441 ttacataata agtatataat ctacatatct ataagttgag tcaattcacc agtatatgtc
    40501 aacttaagtt tatgcatagc tcgtgtacaa gcaatatata acaaactgcg gtcataatca
    40561 ctataatatg ttttattatt tactgaaggt acaataactt catcaaactc taaacctttt
    40621 gacattttaa tagaagttat ggatactcct tttgtaaagc tagaactttc agaagatatt
    40681 aagtgaacac tatattcttc tcttaacgca tcatatacag ctttagcgtc attatctgtc
    40741 tttaatataa taccaagagt cgcattatca ctctttttaa attcttcaat ttctattttt
    40801 atcttattta tttcatcttg ctcgttatta cattttaata aagctggttc ttcaccatgt
    40861 cgttcaatag gctctaatga agatatgtct tgaatctttt tggcgaaatt aataatctca
    40921 aaagtagaac ggtaactctt gttcaacata actagttccc catcattata tagctgtttc
    40981 atatcatcta atgtatgagt atgattagga ttaaccaatt gtccaaaatc tccaagaata
    41041 gtctttttac acttaaaaag taagtttatt acagcatatt gaataggtgt ataatcctgc
    41101 atttcatcaa taacaatatg ccttataatc ttatcttctt gtataccttc atatgcagca
    41161 tgaatatata taaatgggta tacatctgac cattcaagtg ttttcttttc tgccatcaca
    41221 aacatgtttg atatattcat ttgtttaaag aaatccttat atagtgtaag agtatttttt
    41281 attgtcaaca ttccattcaa acttttaagt atacttttta cctttggtaa atcttcttcc
    41341 ataatattat ctgattcaaa tttataatga atgtcttcag ctaccttttc taatctcttc
    41401 ttaactggat atctgttata tgcctcaaat ctactctgta tccagtcact tttagctgta
    41461 aaacttccaa aagtgtagtc ttttggaata aaaatcttat ttggcatttg ttttatataa
    41521 tcatcaataa gttttacaaa atcaagtgta gatttaaaac gcactctttc agaccattta
    41581 gcatcattta tttctaatgg gtctttctca ctttcaaaat taataactct atctaattgt
    41641 acctctgcta tattttcaaa acttaattca cataatggct cttctccaag ctcaggaagg
    41701 acattggaaa tatagtctcc aaagacttta ttaggtgata ggataattac attatttgct
    41761 gatattttat ctttaaatcg ataaagaaga aaagcaattc tgtgtaatgc tatagatgtt
    41821 ttcccagaac cagctacccc ttgaataatc agtgtatcag ctttatcatt tctaataatt
    41881 tgattttgtt ccttttgtat tgttgaaatg attgacttca ttttttcatc tgaagtgtga
    41941 ctaagttctt tttgaagaat atcatcttgt atattaatgg aactttctag tgcatattct
    42001 aattttccat ttttaatttt aaattgtcgt tttcttgtta tttctccatc cacccatcct
    42061 attggagcat catatccagc ttttccgatt tcataatcat aaaacatact ggcaattgga
    42121 gaacgccagt caagtattat aagctcatct tcataatcaa atgcaaatct accaatataa
    42181 tacttagatt catcatccat atctttcagc ctaaaatcta ttctagcaaa gtatggagaa
    42241 tctttgattt tattaatctt atctcgaact tttaccataa aagccccata gttatctatt
    42301 tgttttagtc cttgttcatt ttgaaacatt tcatgtgggt ctatttcacc acgatttttt
    42361 accatataca ttttagcgtc catataatcc ttatcaagct tgtcaacaag attttcagct
    42421 ttcttaaaag cattgtctag cttgttattt atctctatta gatgtgcaat ctcatctgga
    42481 aaaaaagtta ataactctgc atcatattca cacatattat gtttagaatt agatgcaata
    42541 atatcgcaat ttactacttg tttattttca gacatttaaa tcctcctttg ttaattaagt
    42601 acttacactg aatcattata cttaattgtg ttttggagtt tttaatcatt cttgctattt
    42661 aacttaaatg ttagcttttt agctttaaag ttcctttttt aaaaaactaa atctttctat
    42721 atttattacc ataagtacac ttacaagcaa aatacattaa aagcagaaat gctcttatat
    42781 ataaaataat tcaaacaaaa aatatgtggt aaacttttca tttaatctac aattaatttt
    42841 gtctattatc tctttcttct acacaaggaa gaataaattt ttgagtagga tatccaaatt
    42901 ccacaagcaa ttctgcttct gcaaagccca acttctttat catatctcta tgtcctgtat
    42961 cagctttgtc accctctcga aaggtagtaa ttgaaatatc tgtatctatc aagaaatctt
    43021 caataacttt cttcaaaaac acttgtgcaa tgtctgaatt acgatactgt ggatgtattc
    43081 caaaaaaatc aatacttcta gtttctctat taaacaccat atttgcaata gcgacattat
    43141 taagttttaa tattaaagct ctttcttcta aaatatactg ttctaattga tatatatatt
    43201 cttcctcttg caaatttgga aatccatcta tgactaatct cactaaattc atccataatg
    43261 gtatgtcaga tatacttgca agtttaattt ctttttccaa ctctagtaca ttctttgaaa
    43321 ataggttatc ttttttcaaa acaaatctta gctgcaaagg ataaaattct tgttctttcc
    43381 tatatttatt tggagatttt ttatacatag ctttaaatat agaagtgaat gcctgttgac
    43441 tttcatatcc agctatcaat gcaatttcaa taattggttt ctttgaaaat accaataatt
    43501 ttgctgcttc tgtcaacttt ctccgcttta tgtaatcatg cattgttagg ccaacagaag
    43561 ttgtgaaagt tctatgcagg tgatattttg agtaatgaac agcattagca actatatcta
    43621 aatccagctt ttctgataaa tgctcctcta tatagtcaat agcagttatg acattaatta
    43681 ctttgtaaga cattgcagct tccctccttt tatccatgca acattatatt aattataact
    43741 tagttatatt taatgaatct taggtcagtt tacaaggaac tacacgcaga ccacgaaatg
    43801 gggctgctta caacaaataa aagctgaaca tcaagcacag ggaaagcgcg aggtgttcag
    43861 actgttttgt tgtctggaat ttccaaaggg gctttcccct tggcacacga ctttacttgc
    43921 aaagtgtagt gtgttatacg ctctgttggc gttgccgtaa aaatgccgtt gccatcaggg
    43981 aaggcaaggg catttgaagc ggcaggaaaa cagggctgtg attgcatagc gtgaagtcac
    44041 aagcgcaagg cgggtttcag cagcatacat gggtatatga aagctcccgt ccctcgtcct
    44101 acgctccaac ttgtagccac actcacgaaa aagcagacgg attttcctct caaaattgaa
    44161 ataggcggga agccatttta gggctttccc atcttgattg cccgtcagca aaagcagacg
    44221 gggctgtcaa cggtggcaca tgaaatgcgc cgttcatctt gaccattgac tggctcggct
    44281 gactttgcta ttttctatga ttgttagttg cttgatacag atagttgcct tatcaaatcc
    44341 aatggtgtgg taaaagatat tacagcgctt actctatcgc cagaacccca ttttaccagt
    44401 ccaaaatcaa catttgcacg ataggcacat tgcatatcat atatactatc cccaatataa
    44461 agcagttcgt tgttttgaca ttttgtcagt tccatgtatt tcaataatgg tactgctttt
    44521 ggcttatgct ctagagtgtc attggagcat actacagtat taaagtatgg tgctatgtca
    44581 aagctcagaa aatcgtttct aaattcttca tgagttttgg atgtaacaat tccaatgcca
    44641 atatttaatt ttatgagttc agtaagcatt tcctttattt ctttgaacac aagaactgta
    44701 ttcttatact tttccatatt cctatcccac attgatagag caattgttat atcttcgatt
    44761 ttcaaataac gtaaagcgtc ctcgcctgtt attcctaaag caaaagacaa ttctttgata
    44821 ggaattatct ttctattgat ttgttttatc gtgtcttgta gagagtgtaa aatggcgtat
    44881 tcagtatcaa tccatgtgcc gtctacatca aagacgattt ctttgtaatc cattaatttc
    44941 tccttaatta acctaatcga aaatcactgt ccaagtgtct gtacgacatg cttcaaagca
    45001 cattttaatc tgttcttctg tatttttttc tgtggcgagt tcaggaagtt cattttcgga
    45061 gaaataagaa aactccgtag tttctatatt ttctttgaat gtacccccga taacggtaca
    45121 aagaacaaat attttgcata ctccgtaagc atatataggt aaattgtgtt tcgcacggtc
    45181 ttgaattgca ataatcctgt cggcggttat atctaatcca gcttcttctt tgacctcttt
    45241 aatagtattt tccttgactg ataaatttac ttcaacccaa ccacccggaa gcgaccactt
    45301 ccctgtattt tctttaacaa gaagtatttt tccattttca aaaataacgg ctctggtatc
    45361 aagttttgga gtttggtatc cgctttcatt gcaaaaaaga tttcttactt tttctgttga
    45421 tatgtcagtt ttatatgcta tcatttcggc ggaaatttct cgtattctct catatcgctc
    45481 tatgtcgtat atatctttcc cataagttat tccggcttga gcaatgcttt gcaattctat
    45541 cgcccattcc aaccattttt cgttcataaa attacctcca gttttccgaa gaatatatta
    45601 taattagtta ctgagtagta aaatatattt ttaactaatc ctgctttgta tgttgaacat
    45661 attctataat tgtaccatct agatgtctca atgtcatatt atatcctgta ggaacttttt
    45721 tcttatctct tactacaact gctccattat ccaatagata acttctccat tcatcaacag
    45781 aatcaaccat aaaagtagat tttgtttcta taaatggttt aagagcatca tcagaaccag
    45841 ataatagtaa aacatttcct atttgcgcta attccaaccc aacttcttta taagaaaaac
    45901 gcaaagaaca tttttctttt aaaagattct cataaaaagg tatggctttt tctatatctt
    45961 gaatataaaa acgtgttaat atatcatata ttttcatatt ttccccctat atatctatat
    46021 agtatcactt ctaaattata ccactctaca aattatataa caataaatta agcatagcct
    46081 tttgagcatc ttaagtagac cttaacaata tattggggtt acattagaat aataaattaa
    46141 atctaaatta cactaagtta gttataaatt gattatctac agttacatta gaatacataa
    46201 attaaatcac cttgatatta tttaggataa aatttatgta gtagcagtaa atgttcttct
    46261 aattatcaac taacaaacga taatctttaa ctttctatat aatgggtaac atcattttcg
    46321 taagatattc actagctgga cgattgatat catttaaata ctggtaatat atatcgccat
    46381 gaagtttata tccattgcta tttgcccatg aaaataagtc ttctaaagta gggtcttgta
    46441 attcataagg tcctaaatca attgcagtta ttattttctg tgcaggaaca atcctttgta
    46501 gaatctcatt tttcccatct atataagtgg ctacaggaaa ccctacttca acatccaatt
    46561 ttgctaaatc catgttatga aaacatacaa tcggtgctcc tgaagataaa attcctctct
    46621 cctccagata tttagaaatt ttttcaaaac tttgttttga aaactctgaa aactctacca
    46681 taaagtcaat tgtttttcgt attgccaaaa aacagtactc agattgttca gctattgtta
    46741 tattggatat tctagtcatt ttattcctcc attactttat tttcatttct aatcttttta
    46801 taccaaatta tacgaaaatt cactgtgtaa ctaattattt catatgaata taaaacataa
    46861 cctccttcca tttcttatat cgaaagtata gcaaaaataa tctcatcatt cttgtcacgc
    46921 agtgctctta taatcagaac atacttaaaa gacttgccta atttttaggc aagtctaaaa
    46981 gaaatctttt tctataaaaa atttatacaa acaattaaaa tatcaaacat caaaatttaa
    47041 acaagtttca ggttcatctt ctattcttgc tattttaaac ttacatgcaa ttaatactaa
    47101 agatactatt ggatttataa tatttaataa agcgtatgga ccatatgtta gtgcagatac
    47161 acctaatgtt gctgttatat acgccccaca tgtattccat ggtactaatg gagaagttaa
    47221 agttccacta tcttctaaag ctctcgacaa catcttagga tgtatacctc tctttttata
    47281 ttccttatta tacattcttc ctggtataac tatagataga tattgttcac ctgctattat
    47341 attggtaatt gtacaagtta ccatagtaca taatactgtt ccaaatacac cctttgctaa
    47401 tcttagtaaa gaagatgcta ctacttcaag catacctgtt ttttctaaaa tacctccaag
    47461 agataaagcg catattgtta aggatacagt ggacatcata ttcataatcc cacctttaga
    47521 taataaagca tctacctcct gtatttgtgt tgacgaaaca tatccatttt gtgctgcatc
    47581 taatatcgta ttcatagatt ctccttgaaa aactactgca aacaatactc ccaatacagc
    47641 acctactata agccctggta tagcaggaac tttaaataca accaatccaa ttactattgc
    47701 tggagctaat aataatactg gtgataaagt attaaatgta gaatctaatg tagacctaat
    47761 taattctatt tgttttatat ctagtgcttg acctgaatac ttcattccaa ttacaccata
    47821 aattactaaa caaattaata atgatggtat agtcgaatat agcatatatt ttatatgtgt
    47881 aaacaaatct gttcctgcca ttgctggagc taagttagtc gtttcagata aaggtgatag
    47941 tttatctcca aagtaagctc cagatattat agaacctacg attaatccaa ttggcatacc
    48001 taaactttga ccaattccta aaagagctac tcctactgta cccattgtgc tccaagatga
    48061 acctgtcgca agagatacta ttgcacagac taatgttgat gctactaaaa aaatatttgg
    48121 tgataaaatt tttagtcccc agtaaatcat acatggaact actccactta ctatccaagt
    48181 tcctataagt acgcctatta taattatgat taagattgct tgcattgcca tctttatact
    48241 attaaacata cttaattcta actctttcca tttaaatcca agtctatata cagccacaag
    48301 tcctgctact gctgctgctc ctattagtgg tacatgaggt gatgaaccat acactaatac
    48361 tcctagactt aaaaataata tcaaacaagt aattggtatc attgcatcaa acagacttgc
    48421 ttttctacat tctcgctctt tcataaaata gtttcctcct aattatttaa acactacact
    48481 ataatttttt ttgaaacata tttgcttgta ctagatgaca tgataccccc ataagttaat
    48541 aaaaattcta aattgtcacc taatttataa tcatattttg tgttacttac atctagtatc
    48601 atgtggtctg aacttgcccc taatattttt atatcagtgt ctattggaat taaagagtca
    48661 atatttatat cttgtttacc tatagctatg attgcccttt ttaagattcc cttatcttca
    48721 taaacaggtt tatttctaaa ggcatcaact cctatttctc caataggaac tgatggtttt
    48781 tctttacatt caactacttg gcatattaat ttaaatgcat cttgatatgt tccatttata
    48841 ttttcaccgt atgccgtttc tctaccaagt agaatggact cgcctattct caaattagta
    48901 ataccttctg gcatattatt atttatcaac agatgaatcg aacttgaatt acctccagat
    48961 actatttcta gatttattcc aaatttttct tccattcttt ttgctatact taccagtctg
    49021 cctatatttt ccctagatgg tataatagct ccataacagg ttaagtttgt agctatacca
    49081 attatttcaa tattttttaa tcttactatc tctcttacat tactaaaaaa gtcttcttca
    49141 taaaagtatc cttctcgtaa atcgcctaag tcaaacataa gaactatctt atgaataata
    49201 tttttacttt cacataattc atttaatttc tttattgttc ctaattctga gttaaaacta
    49261 atatcgcaat aattgataac ttcttctaat tcacttaaca ttgggattct aatcaatatc
    49321 ttaggtagat ttatatcttg taaatttttt aagttttgta ttcttgaatc tgctatatgg
    49381 tctattcctt cactacatat ttcttctact atttcttttt gtgcacaaaa tgatttagta
    49441 acaaaagata tcttaatatt tctttcatga cacatctgcg aaattaattt tgcattatgc
    49501 tttaactttt ctatatctat ttctaaccta ggatacataa tctttcctcc tcaaaattca
    49561 aactttttaa caggagctta aaagatgctt cttcatattt tttagataaa acacccatag
    49621 atgccataat atagtcatta tctattaata tctttgtttt ttcctttgga aatagtaatt
    49681 cattattttt attgtatttg agcatattat ctaatatttc aattctacta gggagcctag
    49741 taagtgctcc ccctgtacca actatatatc ttacttctgt taaatctttc ccttctgcaa
    49801 ttttgacttt tccagttgtt ccatagatat ttcttatttt tcctgaatgt cttagcatag
    49861 ctttaacaac agcttctttt gtcaacctct caacaaataa tatttcttct tttgattttg
    49921 gtattggagg ataattctct attactgcat caatatctat agatagttca ctttgtaagt
    49981 tttctttacc tataacttct actatattct tcatatttac atatacacct aaatccccct
    50041 caacacttct ctttgcagta ggttcaggat taaccaaaat tttattaata tagtcacttc
    50101 catctgtaac agaatgtaca tcagtagttg ctccacctac atccagagtt aataaatctc
    50161 caatattttt atataaaagt ttagaagctt ccattacagc tcctggggtt ggagtaatat
    50221 tttcattaac catttcttta atgtatttca ttcctggtgc tgtagttatg tgttcttcaa
    50281 atacactttg aatgattctt cttgtaggtt ctatattcaa taaatctatt ttagggtata
    50341 cattttcagt tatataaagc ttataattag tatcttcaaa tattaacctt atttcctctt
    50401 gattttcaac attaccagca tatataactg gtatgcctag attcatagaa gctatcattt
    50461 ctgcattata aatagctgta tctctttctc cataatcgac tccaccagct attaaaatta
    50521 tgtttgggtt tatttctttt attttattta aatcagttct tttaattcta cctgatgtta
    50581 tttgacgaat aacagctcca gcccctaaag ctgcttcttt agctgctttt actgtcatat
    50641 catagactaa tccatgaaca gtcattttta atccaccagc tgcactagaa gttgcaaaca
    50701 tatcattata ctttatatca tctacagata atttattagc taaatcttta atagcacctg
    50761 ataagccatt tcttacatcg ccaccttcaa acactgttgt tggagcttga ccttgaccca
    50821 aaaatatagg attgttagta ttaatatcat ggaaagcgtt taccactgta gtagtacttc
    50881 caatttcagc taccaacaca tctattttta aagaaacttt gctattttcc attatttatt
    50941 actcatttct cttctttttt caactaagaa agtggctaca tgtatgcctt tgctgtttct
    51001 tccaaatcca gcatctatgc cttgttcaac agctatttca ggtgttactt gtgttcctcc
    51061 acacgcaatc attactttat ctcttatacc tttttctaca caataatcgt gtaatttttt
    51121 catgttttta tagtgaatat catcatgact tattattgta gatgcaagta ttgcatctgc
    51181 attcagttca atcgctgcat ctaccaattt ttctacaggt acagaagtcc ctagatagtg
    51241 gcattctatg ccatattttt caatacctcc atgttttata tctattattt ctcttaaacc
    51301 aactgaatgt tcatcttctc caaccgtagc tgaaactatt ttcataggtt tttcttctat
    51361 atctgctctt atttcttcat cagttagtac cttaggttct tctggtatta ctaaattgtt
    51421 taaatctata tcaaacggaa ctcttccttt cacttctatt ctagtccctt cagattcatg
    51481 cataacttct ctacttatga cctcaatttc ttgtaagttc atttttttga caaattccaa
    51541 agctgcaaac tctgctgttc ttttatcagt aggaagcatc attgttatca ttacaattcc
    51601 atctgcacac cattccattt caggcttaat tttagttcca tttctgtact catatgattc
    51661 ttttagtcta ttttctacat tatcaaaatc gtcaagctca tcaatatata ttattttgtc
    51721 tggattttca aatgtacatc catctattaa cattgatgga ttatctatag cattttcatc
    51781 atattgagct acattattgt atccaaagtg agcagttaca ggtgctaaat aatcttcttc
    51841 tctttcataa acagtacctt caccaactcc accttttatt tttctagata ttccatcacc
    51901 atttctttct ggataatttc cagaatcaac aaaaaatcct tgttccacag attcaaaata
    51961 tccaccaact tcagatattt cttccatata taatacagct ctttctttaa gttctcttgc
    52021 tttgtctctt aattcaccga catctttaag ttctatcata tccataagcc catccatacc
    52081 aactaaagct tgctttgctg tatcacatgc ttctatattg tatatatgcc aaggtacatt
    52141 tctaccttca tcaggtgtta tagttgattg tatgtcagct ctagttaata ctgatgttaa
    52201 taagtttaat acatgagtaa ctgttgcttc tctagttgat gattccatat atttagtatt
    52261 catttgagct ctcatcttat aatcactaaa taactctcta agtgcaacag cgtaaggtaa
    52321 gtctattttt aaacatggtg ctggaggtgc tgttggtgga actgttgata agcatatatt
    52381 atttttatct atacctattt tttctgagaa tatagagttt aaagcgtgtt gaaccataag
    52441 ttcaggcatt accttccatg cttctctagc agtagcatta gcattatgtg ctccatcaat
    52501 ttgagctata ttggcaaaag ccattatttt ctttgcctca caagcatcta caaaagacct
    52561 taccatgttt atattcctat acagaacatt atattgtggg tcttgatgtg ctccattgac
    52621 tccttcctca gcaaacatta ctgctacttc aggaccagca acaccactta catatgaatg
    52681 ataattaata ggtctaccaa cttcttcttc tataaaatca agagccttcc tttgagctct
    52741 tacttgtttt cttgttattg gaactccacc tataccttgt ggagttcctt ctataagccc
    52801 atcaaaatgt gattgtccag cagttctgat aaccattaga tggtcagctc catgatgagc
    52861 tgccattctc attcttctta tatcatcctc aaatctacca gaagctattt cagtagtaat
    52921 aactggactt ggttgagggt ctatattatt gaaatactta gatgatggta gccctacact
    52981 cttctttaaa ggttttgtac agtctttata tttaaaaggt cccatttcaa gattttccaa
    53041 gtgttctctc caaacccaac ctcttcgttt tggtttatat ttatccaaat cttttaatat
    53101 atagtctata tccaattttt tattttcctt taacatgatt ctaccccttc tctaaataaa
    53161 catgtaactt catcccaata ttcaccctta actaataaca aacctgcttc tctaaccgtt
    53221 atatttttag atttagccaa tttataaact acatgacctg ctcctttacc tataagacct
    53281 ctttccataa ccccttctaa aataggtttt acttcaagag aagaaaatcc cattctcaac
    53341 aagacagacc tttctattga tggtgttgta ttctttttac caagttctat cattggttct
    53401 actatctggg tagctaaact ccaaaacctt tcttttaact catcatcact cagttcttga
    53461 agatgttttc ttctaacttc aaaatcatcc tctctttttt tcatgaacat tcctccattc
    53521 gtattgcttt aatcgaattt tctgaatttt tattttatat taaattaaaa aacaataatt
    53581 actataaatt atttaataca tcaacaacaa aatctcttga actttttact tcttccatta
    53641 aaaattctat atctcgatta cttagcttat caatattatc aatgtgatta ttagatatac
    53701 aattttttat aaatgacttt cttattttat tcatatcaat atcaacacat ttcaataatt
    53761 ctggtctttc tggtaatatt aagtttactc ctgcaatttc ttctcttgga tttccaaatt
    53821 ttatatctat tccattttct cttgcaaagg taagttgtgg acatatatgt ttacctgcac
    53881 ccgtatattc tgtttcttgt accactataa ctttatcttc atctaactct tgagctaaag
    53941 agaatgctgc tgctaaagat gtatttcctg ctggacctct ttctatacct tctagctgtg
    54001 ccaataattc agttgtataa aaaacttctc cttgttttac taatacatat ctatccatat
    54061 atctaagtgg tctagctgca gacctaggta catctgacct atcaggccat gtacagtatg
    54121 gtatcccaaa acctgtatgt cctgttgtaa atgatttttt attaaattga ttatcactag
    54181 ccatgtgtaa tccttttaaa tctacacttg ctcctactac tttagtatta atagaaccag
    54241 cttttatcaa tcctcttgca gttccagtaa gattaccacc acctgcattt gtacaaacaa
    54301 ctatatcagg gtctttttta tacttttctc taaattggat agctaactca taacctaaag
    54361 tttctacacc tgcaattcca aatggtgaat ataatgatgc gttaaaatag cctgtttctt
    54421 ctaataaaac taagaacgta taaaataact ctggtccaac agttaactga acaacttctg
    54481 ctccatatgc ctcacatttt cgcgcttttt ctataatttc aggttgacct acaccattag
    54541 aatcataaca ttcttgaact attatacatt ttaatccctg cattgccgct tgtgatgcta
    54601 cagctgcacc atagttacca ctggtagctg ctattacacc tttatatccc atttgtttgg
    54661 catgatatac tgcagtagct gctcttcttg ctttaaaact accagatgca ttcattgctt
    54721 catcttttac aaatattcta gctcctttac cttctttagc acattttcta gctaatttag
    54781 tcaaattttt aagctctatt aaaggagtat ttccaacagc atactgtgat tgaattgctt
    54841 caatatcttg taatgtatat cctgtttcac tcatcatttt ctcataatca aaccctattc
    54901 cctcttgttc aaaagaagaa taatccaatc cgattgcatt tttcattatt tcgttatttc
    54961 ttcccataac agcttgataa ctcatatctt tcattgatgt tgaattattc attatataca
    55021 cctccaaata atatttcttt agcttggatt cctatttgga gtaactctgg tatacattta
    55081 ccataatcat gagtataata tggatttatt ttaagtaaat taccttttac aagtctacct
    55141 gtaattgttt taacttctac taagtcgcct atagaagcat cactttgtat aaaaccttta
    55201 acccacattt ctaaggatac tttcttagta tcctctggaa cttgtggagc tctttcttct
    55261 ggagtcaata ctatattgtg tataataacc caatcattaa ttttagcatc cattttttca
    55321 tccccttatt aattgactat tgccttacta attaatttac tgttatttta aattaaacat
    55381 tattttacca attagctaac tgttatctta ctaattagct agttgctatc ttactaatta
    55441 gttatctgtt atcttactaa ttagcctttg attcttcttc caattcaact tctatctgat
    55501 ttcttatatc tcccattatt gctctaggta ctggtatatc caacatagtt ttaagacctg
    55561 gtctagcatt tattattaat ggaatagagt ttactatcat tgcataagta cctactcctc
    55621 caggtatttc aggatttatt tgtaaatcaa tgtttggtat accttttatt gatacatagt
    55681 ctcctgtttt aataccttct gcttctggta ttatctgttg tggatgctcc atttcaatta
    55741 aaacttctcc atttacatat ccatatccac attgtctaca accagcaaca tttccagcca
    55801 atgcctctcc gtacttagat tttctatcta ctgtagtcat tattggctct tttgtttgtt
    55861 ctatcttatc taatttccaa cctaatccat cagctatcat atttattgat tctacaaaac
    55921 ctacatgacc tgctatagtc ttatcttcta caccttttat aaattcttcc cttgttactc
    55981 caacaccttg ttcctccata acagactttc caaatggaga taaatcattt actctcttag
    56041 cttttatact agtaacttct tcacaagtac ctgaaagtgc caatactagt aaatctaata
    56101 caaatcctgg atttattcct gttccaagta tacttactcc attttccttt gcaacttcat
    56161 ccattttttt agctaaatct gcatcatcag cttgtggata tgccatttgt tctgctgttg
    56221 atataacatt tatttttcta tttaataaga aaattatttt atcaaaagcc tttttagtaa
    56281 atgaatcagt tgctaacaaa acaacatcta cacttttttc tctaaaaact tcttcataat
    56341 ttttattgat aataacttct ggtctttctc ctctttcaat tcctaaaaca tcatacatac
    56401 ttttccctga agtacttcta ctacaaacag atactatttc tataccttct ttctttagaa
    56461 tcatattagc catacctatt cccatagctc caaatcccca tattcctact cttacttttc
    56521 tcatatatac accctcctaa aaatttatat attctcaata attagttaaa gcataaatcg
    56581 tgccaacttt aaaattaaag caaatattta ttggaacgtt gaaactataa ttattttatt
    56641 atgtattttc ataaataaaa aataatattt cttatgagaa ataaaaaaaa gagcaaaata
    56701 ttttgctctt ttataataat tttgctcctc tattttgctt ttttatttta ctttgatttt
    56761 gtttttttat cttgcttatt tataatattt tgatattata tttttttatt ttatactgta
    56821 aattttgcct attcatacct aaaattgatg cagctttagt tatattgtat gatgcctttt
    56881 ctaatgattc atatatatac ttttcttcta tctcactgat aatcttacta agtgttttgt
    56941 cctccaaatc gtttaaagaa taattgttac tctctttatt ctctttaaga ttgtaatagt
    57001 cgtttagatt aatcatactt gtttctattt gtacctcatc ttccatcata ctcatagtac
    57061 aataaattat gttttctagc tctcttatgt taccttgcca atcgtaattt tttaaaattt
    57121 taatagcttc atctgaaatt cctaccactt ttttatttaa ctttttatta tactttgaaa
    57181 taaatttttt gcacaataga ggtatgtcct cttttctatc tctaagagga ggaattttta
    57241 tatgaattat gttaagccta taatataaat cttttcgcat tttatgctcg tttaaaatta
    57301 cctttggact ttcatttgtc gttgcaataa ttcttacatc tataggtata tccttagttc
    57361 ctccaaccct tcttacataa ccttcttgta aaacccttaa tagtttagcc tgtaacataa
    57421 taggcatgga atttatctca tccaataaca atgtcccttt gttagcttgt tcaaataaac
    57481 ctggcctatc tattgctcct gtaaatcctc ccttgctagt tccaaaaagg ataccttcga
    57541 atagtgattc cggcaaagct gcacaatttt gtgctataaa tggatagttt ctcctattac
    57601 ttccatagtg aatggactgg ctaaataact ctttacccgt tccagtttca ccatatataa
    57661 atactgaagc atcagacttg caagctttct tagatttttc tattgcttct ttaatcaaat
    57721 tactttcccc taaaatatca tcaaattcat aacccttttt ttgtctacta ctaactttat
    57781 tgactaaatt ttttttataa tttctattta gtaaattttc tatcgttgtc atattctttg
    57841 atatttcaag tgcccctaca aactcgcctt taatatcaat tggtattgta gtattaattg
    57901 ctgttatctc ttttccattt ttatccagat atttctgaat attgtctttg ataacttccc
    57961 ttttttccaa aacttctaat agtgtactcc tgtttatttt cattttgttg actatatcaa
    58021 aaaatgaatt ggctaaaata tcgtgtctgt tcattttttc cattttttgt acagaattat
    58081 tgtagattat agttttcccg tctttattaa caaaatgtac cccttcatca atattttcca
    58141 atatttcatt cattatttta aaaaatatct cttggttcaa ctatatcacc ccagtaccta
    58201 aatatataaa aacccaaaaa attaataaaa tgttgctatt gtatttatct tatcatatat
    58261 ttatgat
//
LOCUS       DAEQAF010000012        57148 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.012, whole genome shotgun sequence.
ACCESSION   DAEQAF010000012 DAEQAF010000000
VERSION     DAEQAF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 57148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57148
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.012"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            388..2622
                     /locus_tag="KRN00_000880"
     CDS             388..2622
                     /locus_tag="KRN00_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1826759.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIRLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPDDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDINKIKN
                     LTKI"
     gene            2653..3498
                     /locus_tag="KRN00_000881"
     CDS             2653..3498
                     /locus_tag="KRN00_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1826760.1"
                     /translation="MFKEIFLKTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFMDSHNIQLDWEKNYPYDKISNWIFEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            3738..5471
                     /locus_tag="KRN00_000882"
     CDS             3738..5471
                     /locus_tag="KRN00_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1826761.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5863..6547
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5863..5891
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(7077..7181)
                     /locus_tag="KRN00_000883"
     CDS             complement(7077..7181)
                     /locus_tag="KRN00_000883"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH1826762.1"
                     /translation="MDDYIYYYNNFRYQNRLNSMSPFEFRKYLSTERA"
     gene            7806..8051
                     /locus_tag="KRN00_000884"
     CDS             7806..8051
                     /locus_tag="KRN00_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826763.1"
                     /translation="MNQKKIKISIKMVIIGIFAVIIAFVLSRLFVEYIDELLRSNWQY
                     QLFESESSYIVFANCIMFSNILLEIFLIYICRKFRKI"
     gene            complement(8804..8950)
                     /locus_tag="KRN00_000885"
     CDS             complement(8804..8950)
                     /locus_tag="KRN00_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826764.1"
                     /translation="MVFETFDKTIELYPNAKPIFHSDIGFRLDDESFEEYLGRVFRKR
                     CKGI"
     gene            9046..9695
                     /locus_tag="KRN00_000886"
                     /pseudo
     CDS             9046..9695
                     /locus_tag="KRN00_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429361.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase family
                     protein"
     gene            10236..11591
                     /locus_tag="KRN00_000887"
     CDS             10236..11591
                     /locus_tag="KRN00_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1826765.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(11709..12377)
                     /locus_tag="KRN00_000888"
     CDS             complement(11709..12377)
                     /locus_tag="KRN00_000888"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBH1826766.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(12444..12872)
                     /locus_tag="KRN00_000889"
     CDS             complement(12444..12872)
                     /locus_tag="KRN00_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1826767.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            12979..13572
                     /locus_tag="KRN00_000890"
     CDS             12979..13572
                     /locus_tag="KRN00_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBH1826768.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            13691..14626
                     /locus_tag="KRN00_000891"
     CDS             13691..14626
                     /locus_tag="KRN00_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBH1826769.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDIVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNKIDDTLKARNSYQGCKFV"
     gene            complement(14897..15841)
                     /locus_tag="KRN00_000892"
     CDS             complement(14897..15841)
                     /locus_tag="KRN00_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1826770.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI"
     gene            16159..17589
                     /locus_tag="KRN00_000893"
     CDS             16159..17589
                     /locus_tag="KRN00_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1826771.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            17789..18373
                     /locus_tag="KRN00_000894"
     CDS             17789..18373
                     /locus_tag="KRN00_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBH1826772.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(18477..19256)
                     /locus_tag="KRN00_000895"
     CDS             complement(18477..19256)
                     /locus_tag="KRN00_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1826773.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(19314..20570)
                     /locus_tag="KRN00_000896"
     CDS             complement(19314..20570)
                     /locus_tag="KRN00_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBH1826774.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKSVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            20828..21727
                     /locus_tag="KRN00_000897"
     CDS             20828..21727
                     /locus_tag="KRN00_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBH1826775.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            21751..23199
                     /gene="ddlR"
                     /locus_tag="KRN00_000898"
     CDS             21751..23199
                     /gene="ddlR"
                     /locus_tag="KRN00_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBH1826776.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YRPLIDYLLEYMTNKGVDISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            23258..24064
                     /locus_tag="KRN00_000899"
     CDS             23258..24064
                     /locus_tag="KRN00_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1826777.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDNLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            24090..26009
                     /locus_tag="KRN00_000900"
     CDS             24090..26009
                     /locus_tag="KRN00_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1826778.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINKDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRSIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTPKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTSKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(26260..26607)
                     /locus_tag="KRN00_000901"
     CDS             complement(26260..26607)
                     /locus_tag="KRN00_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBH1826779.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(26594..28522)
                     /locus_tag="KRN00_000902"
     CDS             complement(26594..28522)
                     /locus_tag="KRN00_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBH1826780.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFLEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSTGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNIQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(28933..31122)
                     /locus_tag="KRN00_000903"
     CDS             complement(28933..31122)
                     /locus_tag="KRN00_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBH1826781.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNDNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITPSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSINATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE"
     gene            31456..32187
                     /locus_tag="KRN00_000904"
     CDS             31456..32187
                     /locus_tag="KRN00_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH1826782.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTD
                     LILNIELKTDKVNYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYR"
     gene            32267..32902
                     /locus_tag="KRN00_000905"
     CDS             32267..32902
                     /locus_tag="KRN00_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1826783.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAK
                     QGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQIFPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(33152..33745)
                     /locus_tag="KRN00_000906"
     CDS             complement(33152..33745)
                     /locus_tag="KRN00_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBH1826784.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(33816..34679)
                     /locus_tag="KRN00_000907"
     CDS             complement(33816..34679)
                     /locus_tag="KRN00_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBH1826785.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANIGKWDEFTYKSLVNALEFKDYLYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLIELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            34842..36011
                     /locus_tag="KRN00_000908"
     CDS             34842..36011
                     /locus_tag="KRN00_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1826786.1"
                     /translation="MLNIRTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSVSVEIDEGYPALINSNYLVDYVKQNAVELFGEENIILKDAPTLGAE
                     DFSYFLRHCEGVFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLAF"
     gene            36112..36588
                     /locus_tag="KRN00_000909"
     CDS             36112..36588
                     /locus_tag="KRN00_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1826787.1"
                     /translation="MKEILINPIGKIRIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDNPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTTVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            37148..37942
                     /locus_tag="KRN00_000910"
     CDS             37148..37942
                     /locus_tag="KRN00_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBH1826788.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            37966..38409
                     /locus_tag="KRN00_000911"
     CDS             37966..38409
                     /locus_tag="KRN00_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBH1826789.1"
                     /translation="MIKISNKRRIPLGEFIYVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(38498..39784)
                     /locus_tag="KRN00_000912"
     CDS             complement(38498..39784)
                     /locus_tag="KRN00_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1826790.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFARGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKKFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(40002..40892)
                     /locus_tag="KRN00_000913"
     CDS             complement(40002..40892)
                     /locus_tag="KRN00_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1826791.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINIKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            41184..41528
                     /locus_tag="KRN00_000914"
     CDS             41184..41528
                     /locus_tag="KRN00_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1826792.1"
                     /translation="MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            complement(41687..43783)
                     /locus_tag="KRN00_000915"
     CDS             complement(41687..43783)
                     /locus_tag="KRN00_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBH1826793.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISREE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEKYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPNFVDSTKKTPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSSNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSLGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FNSDLEEKYDSYIYNPKDPSIQLIDMSENEVGVPNNYKDLEKRSDMLCYTSNAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNGFYKSEFMEE
                     GEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(43796..44956)
                     /locus_tag="KRN00_000916"
     CDS             complement(43796..44956)
                     /locus_tag="KRN00_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH1826794.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAILVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            complement(44975..46042)
                     /locus_tag="KRN00_000917"
     CDS             complement(44975..46042)
                     /locus_tag="KRN00_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBH1826795.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESIILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIRKTVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKDISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            46394..46960
                     /locus_tag="KRN00_000918"
     CDS             46394..46960
                     /locus_tag="KRN00_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1826796.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            complement(47179..48165)
                     /locus_tag="KRN00_000919"
     CDS             complement(47179..48165)
                     /locus_tag="KRN00_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBH1826797.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSKGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNIISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(48195..48890)
                     /gene="pxpB"
                     /locus_tag="KRN00_000920"
     CDS             complement(48195..48890)
                     /gene="pxpB"
                     /locus_tag="KRN00_000920"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBH1826798.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLKIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            complement(48910..50130)
                     /locus_tag="KRN00_000921"
     CDS             complement(48910..50130)
                     /locus_tag="KRN00_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBH1826799.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            complement(50159..50950)
                     /locus_tag="KRN00_000922"
     CDS             complement(50159..50950)
                     /locus_tag="KRN00_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBH1826800.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELESIEVCPLENIEVCSSENIV"
     gene            51538..52167
                     /locus_tag="KRN00_000923"
     CDS             51538..52167
                     /locus_tag="KRN00_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1826801.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAKTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            complement(52280..53794)
                     /gene="glpK"
                     /locus_tag="KRN00_000924"
     CDS             complement(52280..53794)
                     /gene="glpK"
                     /locus_tag="KRN00_000924"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH1826802.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVEDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGLYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            54037..54579
                     /locus_tag="KRN00_000925"
     CDS             54037..54579
                     /locus_tag="KRN00_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1826803.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            54593..57085
                     /locus_tag="KRN00_000926"
     CDS             54593..57085
                     /locus_tag="KRN00_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1826804.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     VCIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
BASE COUNT        20664 a         8583 c         7104 g        20797 t
ORIGIN      
        1 attatgcaaa attattaata tggtattaaa ttatgtataa aaagttaatt atgaataaaa
       61 taattatgcc tttgaaaaat cattaaactt aaaattaatt ataaaaaaac tctaccttac
      121 taactataca gctcacaatc tatctattta tgaaaaaata tgatataatt gcattcaaaa
      181 aggaaatctt tcaatatact agaatttaag cattaactaa ttttatctaa tattattact
      241 aaactaaaaa atatttgtat ttgtagcatt ggagcaaata acttaatgta tattcatttt
      301 aaatacttat ttaaaattta gcatttaaat acttatagca taaatacagt tgtcatcaaa
      361 atttaaagta tcttatggag gaataccatg caaaatcata attatataaa aatgttaaat
      421 aaaaaggtag aagtattatc taaggaatta gatagtagaa attttaaatt aaaaacctta
      481 aatgaaatag attttttttc taaaatacca aacagagaat ttatgtacca atatattgat
      541 gactgtattt cgaaaaatat acatatagga atcatgttat taaatatcga taactttaaa
      601 ttatttaatg atatatatgg atatctagtc ggagaaaatt tattaattac tctaactcaa
      661 aacctattgc actttattcc agaatcaaag ggaatagtcg cttatttaaa aggagaaggt
      721 tttttaattg tacttccaaa tgtatcaaat aaagagttaa ataatatggg tgcaactatt
      781 atagagagcg cccgagaatt aaaaataaga cttcctaatg aaaaagaaat atactccaat
      841 gttacattta gtatcggcag cactatctgg aatggtgaac caaacatgac tactttgatg
      901 cttttcaacc aagtatatag tgctttaaaa aaggctaaaa gtgaaggtaa aaatagatac
      961 attctatttg attttaaaga taatagtttt tacaataaat tagaaaatga taaggagttc
     1021 ttatcagaaa tatcacatgt tctacaaact aaacaaattg aagtatttta ccaaccactt
     1081 tataatataa aaaataatac tatagttgga tgtgaggcac ttgcaagatg gagacaccct
     1141 attaaaggac ttcttactcc agataaattt attcctttat ttgaacagtt tggtctgata
     1201 acggaattag atttgcattt atttgaagag aactgtaaaa atataagaag atggattgat
     1261 aacaatgatg tttttgttcc aatttgttgt aacttttctc gtcttcattt ttttaaccct
     1321 aattttccaa gtatgctaaa aggtattact gaaaagtaca gcgtctctac atcaaatttt
     1381 agcattgaaa taacagaaaa tatattaata gaaaatacaa atacaattat tcaacaacta
     1441 gctgaacttc gttcttatgg tttttctgta tcaatggacg attttggttc tggatattca
     1501 tcttttggta tgttgcaaaa tctacctttt gatataatca aaattgatag gatattttta
     1561 tctcataatt taaatgattt taaaaataca accattttgt actctataat aaacattgca
     1621 agagctcttg ggatgcttac agtatgtgaa ggtgttgaaa cagaacaaca tgtagaattt
     1681 attaaaagta taaattgtga tatcgcccaa ggttattatt atgcaaaacc catggagtgc
     1741 aaagaatttg aaaaattact atctaaagag aataattcag agaaaatgtt tataaaatat
     1801 tctgatatag gaaaatcttt aatagagaag atatttgatg gattttttat tatgcaagat
     1861 atgaaaaaac taagagctaa tgtcactgaa gacattcaat ggtttgattt ttacaacaaa
     1921 actgaaatta catcttttcc taaagtaata gaacattttg aaaaacatat taaaggtaaa
     1981 aaattttcta ttctttacaa aagtataacc ccacataata ctgaatcaga ttcattatta
     2041 attagtggag aagccgtttt atcagatgaa gcttctgaac atcaaaaata tagcaatttc
     2101 tactttagtg caaattgtat aatttcagaa aataaattac tcttagcaaa attacatttg
     2161 gatttaatta aaactgctgg ctatataaat gaatttgaat catattcaat acctaaaatg
     2221 acaaatacac atcttgatga aagtaatatt ttatcacaat tttattcaat gttgcctgta
     2281 ggtataattc gctacgattt atttggtgat atgattatta cttatatgaa tgaagaaatg
     2341 tttgatatta taggttatac aaaagaacag ttttttggtg agatgggcgg aaatttaaga
     2401 gcaattgttc atccagatga tttagacttt gtttataaaa aaagtttgga catgattgac
     2461 acaaataaaa ttgaaccatt tttatataga ttcataaaac gagatggtca aattgtcaca
     2521 gttatgtata cacaatgtaa cctttctgca attgatggaa ggtcgattgc ccagggtatg
     2581 tatgtagata taaataaaat aaaaaattta acaaaaatct agtacaaagt attttatttt
     2641 ggagaaatta atatgtttaa agaaattttt ttaaaaactt ttccaggatt tctaattata
     2701 agagattcta actacagaat tatatttata aatgataatt taaaaaactt aattaaaagt
     2761 tatatgcaag ataatccact tggaatgact aatatagaaa tagctaagaa actccctgat
     2821 aatattgcta aattttttat ggattctcac aatattcaat tagattggga aaaaaattat
     2881 ccttatgata aaatttcaaa ttggattttt gagtttaaaa aagatactac aagctattgg
     2941 aatgttttag aatataaagt agatgttgat gaaaaaacct acataattac tatggccaat
     3001 gatataacaa aactctatga agaaaataag agaaatcttc actactcaat tactgaccca
     3061 ttaactggag catataatag aaaatattta aatgatagat ttgacatatt tataggagat
     3121 tatattgtac taattgactt agataatttc aaaatgataa atgactatga aggtcataat
     3181 gtaggagaca agattttatg tgattttgtt tcacttttaa ataaagaatt aataaattct
     3241 acttctatta taagattagg aggagatgaa tttattgtta tattctctag tgatgttgac
     3301 aaaaattatg tttattcaca gctagaagcc ttaagagaaa attttttaaa agtattctct
     3361 aagtataagt atctttcatt tagttatggt gttgatacag taaaaagaaa tttaaaattg
     3421 acaatagttg aattggataa aaaaatgtat aaaaacaagg agaaaaacaa gaaaaaattt
     3481 gataaaaatg attattaata ttgttatttt aaaataaatt aaaattatct ttcttttttt
     3541 aaacttgtac attagtttat aaatatgtat ctatacaaga tattgacatt aagtactgaa
     3601 gcatatattg tttcagttct tttttgttaa aattaactta tttgacaaag atatcatagt
     3661 ttaacaaagc ttttaattta aatatattga tgtataatat aattaaaata taatagcaaa
     3721 aagaaaggag gaatatcatg agcatactcc taaaaaaagc acccaaatta gcaaaacata
     3781 ttataacaag tttttatata aatcgggata ttgatgaagt attaaaatac ctttgtgaaa
     3841 atgttacatg gattggacca ggagaacagg aatttctcac ttcttttaat gaaataaaaa
     3901 attattttta tgcaggtcaa gatgaaattc cttcttgtga tataaataat gatatatttg
     3961 aaactgtaag tgaagatgag aatagatgta tggtattagg aagatatact gttcgaacta
     4021 aagaaaatgc tcaaatgatt ttagaggtaa atcaacgttg tacatttgag ataattgagg
     4081 atagaggaaa attattaata aagcacatgc acatatcaaa cccttatggt gaaatgcaac
     4141 ttgatgaata ctttcccact aaaattggaa ctcaaagtta tgattatttg caaagattac
     4201 taaaagaaaa aacagaagtt attgaaatga ttacaaataa tatcaatggt ggcttaaaag
     4261 gtagcaatga tgatagtaca tactcatttt tctatgtcaa tgagggattg cccaaaatat
     4321 taggatacac atatgatgag ttcatggaaa tgagtggtgg ttcagcagtg ggtgctgtat
     4381 atccaccaga cttacctaaa gcactagaag attgtgaacg atgttttgca aaaggaccta
     4441 catattcatc tgaatataga atccgaaaaa aagatggaac attaatgtgg gtattagatt
     4501 ctggaatgaa atcgttaaat agtgatggca tagtaaaaat taatagtatt attactgaca
     4561 taacccaact aaaaaacata gaatctgaac taaaattaga aagagagcga tatcgtattg
     4621 ctttgcaaaa tattacagat atcatgtttg agtatgatat tgaaaacgat acccttataa
     4681 aatatcaacg tgtagaaatt gacaaaaaaa ttgaattaga aaattttgaa acaaaaaatt
     4741 actccaaact attagaatct ggtaaaatta ttcaccttga tgatattgga aaactactag
     4801 aagtacttca tggaaatctt cgtgaaacaa ttgagataag acaagtaaat tcattaacta
     4861 aaaatgaatg gagatggatt cgtgttcaat gttcagttat atatgatagt gaccataacc
     4921 ctatcaaaac aataggcgtt ttaaaagaca taactgaaga taaatctaaa ttagaaagct
     4981 taattaatca ggctcaacgt gacccactaa cacaattata taatcaaaga gtatcacaaa
     5041 atcttattga agagtatcta tgtagttctg attccaaaaa taatgatgct ctattagtta
     5101 ttgatattga tgattttaaa actgtaaatg atacttttgg gcatttagag ggaaatgaag
     5161 ttttagttgc tgtatcaaaa atactattac ataacacaca tgataaagac atagttgctc
     5221 gaattggtgg agatgaattt acaatattta taaaatcatt aacaaaggat ttaataataa
     5281 aaatcactaa tgatatttta aatgatgcaa gtaaaataaa agtaaaggac aatcataaaa
     5341 taacattaag tattggtatt gccttcactg atgattcaac taaattatat aaagatttat
     5401 tttctaaagc tgataaagct ctttatctat caaaagcaga tggcaaaaat tgttatagta
     5461 catacgaata ataaaactat ttatacgacc aagaatgaac ctttaaattt aatttcatag
     5521 tctaacaatc aaagaattga agctaatctt atagctagtc aactagttcc tagaaaaaat
     5581 ttagacaata tatttattga tactgctcat ttttctaaag agcaaattta tataaaaaat
     5641 taaactttta tgtacataca gatactaatg ataaacattt agcattagta tcttctatct
     5701 taaaacaaaa tgataattta tctatataaa aaagtgcttt gttgacagag ttcacttttt
     5761 tatataggta cagaatttaa gtataaatac atgttttatt ctatacattt tagttaatgt
     5821 aaaattcctt gattgtactc tctaactttt caacattata ctatttacat accacttagt
     5881 taatataaaa cacttatatt atgcaaaaga catagttgac caaattgcat ttacatacca
     5941 cttagttaat ataaaacgtt ttcatttaat gaactcctat gttataatta atttatttac
     6001 ataccactta gttaatataa aacacctcct gctttcgttt acaactacgc ttttttacga
     6061 tttacatacc acttagttaa tataaaacta ttcttgatat tacttattat atgctcccaa
     6121 gtcagattta cataccactt agttaatata aaacttgaga ttgttaattc tacagaattt
     6181 atgtaaaaaa aatttacata ccacttagtt aatataaaac ttgcgatggc agacatggct
     6241 gtcgagctac ttgcgaattt acataccact tagttaatat aaaacaagat atattaaaaa
     6301 ttaaagcaaa agaatctata gatttacata ccacttagtt aatataaaac gaatatcaag
     6361 tcaagtatat gtatgagaag cttaaaaatt tacataccac ttagttaata taaaacttgt
     6421 agaaagctca tttgtggatg aagttttaga gtcatttaca taccacttag ttaatataaa
     6481 actttttctt tattagataa aagttctccg tcgaatttat ttacatacca cttagttaat
     6541 ataaaacccc aaaataaact gggcattttc aatacttaca catatgcaac tctcttaaat
     6601 ttgcagtgaa ccatgagtag tgcaaatgat aaagcttatc atataccctc aacaccttat
     6661 atttcaagcg ttaagctcta ctttgtaaca aatatcgctc actgcaaaac tatttacatt
     6721 tttattatat cataaatata ttatttttga atatctatac caatttgtgg tataataaaa
     6781 gcaagaagaa ctacaatcta tttagacgta gagtgaagtt caaatactaa tgtttattct
     6841 ttttgaactt gatttttagt tcaaaactaa agtcactcct gcctgtgtga actatacccg
     6901 ctgttttata cagttaaaac atgtaaaaat agttataaag tactagtgta actcattagt
     6961 actcttttta ttatattcat ataattaata tctatatttt aaagtttact atctaaaaaa
     7021 gagcatgtca aataaaaccc tagatattta atttttttag agatacttaa aataaattat
     7081 gctctctctg tacttaaata tttcctaaat tcaaatggag acatagaatt taatctattt
     7141 tgatatctaa aattattata gtagtatata taatcatcta ttgctttaac taattattca
     7201 tatgtatcaa atttccttaa atagtacatt tctaccttta aaattcccca aaatccttcc
     7261 ataggagcat tgtcaaggca acgaccaact cttgtataat atatgtatat ctaacaccat
     7321 taagaaatat atattttata atatatattt cttcatttaa tgcacttaga aaagcaaaga
     7381 aaatacagat tagtacactt tttagagaaa aataaaatta atacatctaa aatattaaaa
     7441 aatactttag ataatctaaa gacacatctc aaagttttta actaaattat aaaactaatt
     7501 acaaatgcta tgtaacgata ataaataaaa aatttacttc gcttaagcga cgtgtcgttg
     7561 aaatatttca tgttgccaac tggttcgtaa gttgctaaga aaagaacact aattatttag
     7621 agttcttttc ttagctacaa gtggattata atacttttaa atctgtgaga aaattgtata
     7681 taataatgat atgaacaagt aaagaaaata caaaaatgac aaaattataa ataaaatatt
     7741 ataaaatcat aaggtcataa ttgttatatt gtagaaacaa agtaaagaga gagggtggag
     7801 aataaatgaa tcaaaaaaaa ataaagatta gtattaaaat ggtaattata ggtatatttg
     7861 ctgtaattat tgcttttgta ttatccagat tattcgttga gtatattgat gaattattaa
     7921 ggtctaattg gcaatatcag ctatttgaaa gtgagagttc atatatagta tttgccaatt
     7981 gtattatgtt ctcgaatata ttattagaaa tatttttaat atatatttgt agaaaattta
     8041 gaaaaatcta atatggtcaa cgtatttcga atcgaatact tcatgattat ttagtctatt
     8101 gtgctagtta aagtttaatt cccatataaa gtaaattgat tttagtaaaa caaatcaccc
     8161 ctaagggtta gtttatggat aagtcatcca aatattaact ctttaatttt tgctatagat
     8221 tcatctttgc tcataacttt acttataaaa aatgaaatat tataagctag aacttttatt
     8281 ctaattctag tcataaatcc tagcatagag ttactttttt tatattataa ataaaactat
     8341 acaacaaaga taatatttag taaaaataac tttcatttta actaaactta aaattcaatt
     8401 actctctaaa ttgacgttta ggaattagtt caaaataaaa aagagtgtat atattgaaat
     8461 tactacattt caatatatat actcttttta aatttctcag ttttccatgg aactttactt
     8521 tatttatttc tgtattagtt gtatttttta tgcatttttc tttaaaatca tattttctga
     8581 ttcaactctt atattataaa atttctttac taaattattc tctttttcta tatcttcata
     8641 tatatttttt aatcgccttt tacctaatct tttatctaac attactaatg atttaactaa
     8701 tatattatat gattttatcg catcttctat tgagatattt aaacatatat ttactgcttc
     8761 ataaaaatca aattcattaa aaaatccatt tttatttaca atcttatatc cctttgcatc
     8821 tctttctaaa tactcttcct aaatactctt caaaactttc atcatctaat ctaaatccta
     8881 tatcactatg aaaaataggt tttgcatttg gatatagttc tattgtttta tcaaaagttt
     8941 cgaataccaa gttattatta ttcgattttc caatagtcca ctataaacaa taataagttt
     9001 gttgctccaa ataatgtaac acttgtagaa agatgttaca gatatataaa agatagagaa
     9061 tgtagttttt ctcctaatac tattagaaat agaaaaaata tgattaaaaa tcaaattgaa
     9121 gttttcttta aagatatgaa attaatagat ataactcctt ctattttaca gtcttatata
     9181 aataacatat acaatgagca catgttaaat tcaacaaaaa accaagtcga ttttataaag
     9241 tcagtattga aagaatctta tagattaaaa gaaatatcag aaaatatttg taattttgtt
     9301 acaaccccaa tcaaaaaaaa tagttcaact tctaagcttt atacaaaaca aaaagctcaa
     9361 ttattattag aaaaatcaaa aaatattcct ataggtatac cagttttttt gatgctaact
     9421 cttggattac gttttggtga agctgtatca cttatatggt cagatgtaga ccttgataaa
     9481 aaatctcaca tgtaaatcaa acattagttt atgtatacaa taaaataatc ttcaaagacc
     9541 ctaaaacccc tatatccaaa agaaaattat ttgcttctga tgaacttata agtttgctta
     9601 aaggggaaaa attaaaacaa aataagttga aattacaggg tatattgaaa aatgaatttg
     9661 atttgatatg cttaaataaa agattcaacc catgagttca accaactttt gttgttcatt
     9721 ttaaaaaact attaagagat aataatccta gagatataaa agtacatgaa ttaatacatg
     9781 caaatgcgac tttgatatta ctttcaggta ctaacataaa agctatttat aaaatattag
     9841 tacatgcaga tataaaaata gctatgaata tatattccat attctcactt attagatgaa
     9901 atgaataaag aaacatctga aaatataagc aaaatactat tcaaataatg ttcagtttta
     9961 tgtcaattaa atgtcactca aagtgctttt tttccatttg tcagttaaat gtcacttaaa
    10021 gtaccttttt cctatttgtc agttaaatgt cagtaatata taaataagat atatttataa
    10081 gacccttaaa atcactatta tttaataaaa tttataatta tatactattt gctgttgaca
    10141 ttggtattat accatagttt atcatttata ttagaataaa attattaatt aatagtttcg
    10201 taattttata atagatttac agggagtgat aataaatgga tacaaaaata tctataaacg
    10261 aaaacatgag tctaggtaaa agatttttta aatacctagc accatctgta gttgcaatgt
    10321 gggttttctc actatataca atggttgatg gaatatttgt aagtaaagga gttggagaat
    10381 tagctttagc tgctgtcaat atatcaatgc cttttattaa ttttatattt gcagtttctc
    10441 tattattttc aactggtgca tctaccataa ttgcaatcta tctggggaaa aaagatatta
    10501 aatctgctaa cgaagtcttt tcatttaact tagtatcaat aattatatta tcaataatta
    10561 tattagctat aacttttttt aatttagata gattagcact atttttagga gctacagaat
    10621 ctacaattgg tatggttaaa gattatttag gaataataat attttttaac ggattcttta
    10681 tagtgtctta ttctttagaa gttataataa aaactgatgg ctttccaata ttagctactg
    10741 ttggtgtaat aatatctgct cttacaaaca tcatacttga ttacttgttt gtaattgaat
    10801 ttggatgggg tgtaaaaggt gctggtattg caactggttt gtctcaagtc ttttctacta
    10861 ttttcttctt aatacatttt ttaagaaaaa actctacttt gaatttttca aaatttagaa
    10921 ttgattttaa gacacttaga aaaattgtat ttataggttt tcctgattca actactgaat
    10981 taagttgtgg tatagttgtt ttacttttta acttaagtct tactaaatat attggagaaa
    11041 atgctcttat ttattatagt gtcataaatt atataaatac attagtactt atgactatga
    11101 tgggtataac tcaaggtatg caaccactta ctagctttta ttatggtgca ggaaatatag
    11161 ataatgtaaa aaaattatta aaaatgggga taaaagccac aataatagca tcagttgctg
    11221 tatttgcaat ttgtatggct ttttcaggac caatagtctc tttatttata catccagaag
    11281 aaacaatgct attcaatgaa ggagttcgtg tatttaaaat attctctata tctttcttat
    11341 tggtaggaat taatgtaata atttctggat tctttgtatc agtagaaaaa ccatcaattt
    11401 ctactgttat atctcttggt agagggcttg taatagttgt tttaagtcta atttcaatga
    11461 tactaatatt tggtggacaa ggaatatgga tgactactat tgtttctgag tttatatgtc
    11521 ttattttatc tttagttttt ctaaaaaaga atttttctac attagactct aatctaaata
    11581 aggttgctta gatgataaga gtagcaatat atgaaaatat ctaaataaaa aatacctatt
    11641 atacaatctt gcaaatatta aacctttgca aaaattagga ttatataata ggtattttat
    11701 ttatgtaatt attttatttc taaatatcca tagccatctt ttattaaagt tccttttact
    11761 tcatattcta caggtttttt aaatattgga ccatctacga caaatgtatg atactctcca
    11821 tgttctccac atgggtctgc accagcattt tttatcttct ccacaagttc tctagttaat
    11881 ttttttccta aaaattcctc tcctaagtgc tttaagttta cttttgttac aacactacaa
    11941 aatccactgt ctataaattc atatactaaa tcctctctac tctcttgcca taatggtaaa
    12001 tctactttca taccaactgc ttcacatcta tcagtatccc attttctatg actttctata
    12061 tctatatctc catatgcaca tatcgttgct cccatgtttt tagcttttat taaagccctc
    12121 tcaaagctct cttcatatcc ttctacgcca cactcagcaa ctaataaagg taatcctatg
    12181 ttgctactta cttgcttaag catattatat tctaaattat gtgtccatga ctttccatgt
    12241 tcttcactta tagttgtcaa gagtgccaca ggcttatatc cttttttcaa cattcgattt
    12301 aatgctaata tactatcctt accaccacta aatgacatta caaatttttc atcagccaat
    12361 tttaacacct ctttcatcta actttgtttt attaacataa ttataccaaa tttttgagtt
    12421 gcatagcaaa ttatattaaa ttgttaattc actataaaga atgtccctaa tattaaaagt
    12481 ataaccccta tgtatttgta taaatgcatt gtttcttgtc ccaaaattac gctatcaata
    12541 aaaaatccaa ctaaaacttg ggatacaaga gttaatataa gtgtatttga tactcctaaa
    12601 tttggaattg cctttactgt aaaatatatt attagacctc caaatactcc tcctaataac
    12661 aacttataat taaaaccatt tatagatact agacacttta agtcacctgt aactattata
    12721 cttgccaaaa aaaatattgc tcctacagtt aagcttataa aggtggccac taatgctgtt
    12781 gtactttttc ctagctctcc atttataaaa gcttcaagag ctgtagaacc acctgctaat
    12841 aatgcaaata ttattgccca taattttgtc atggacaaac ctccttctat ataattctat
    12901 taatagaagt ttatgataca acctattaat taattactaa gtatagttta atttttatac
    12961 actaggcttt atttggatat gaatttctgt tataattgtt ctatcgattt tggaggtgat
    13021 tttatgtaca caaattttaa tatcgatttt aataacttta ataaaaaaga aaatgctatt
    13081 aaatttatgt taatgggagt attactcatt atattaggat tattatgcct tacatttaag
    13141 acattaggta taaaattaat ttcttggact tttggtattg cacttttatt ctttgcatat
    13201 ttaaatttaa aaaatattaa tgaactaaaa agatatgcta ctaaagaaga aattaaaccc
    13261 tctattaata tccaatgggt tctaataatt gcatgtatat tactttttgt atttcctcaa
    13321 aaaatacaaa gcatattttc attattttta ggattttatt taatctttaa tcaactagta
    13381 gcacttgtaa atagtaagaa taatccttat tctaaattta caacttggaa tatagttaag
    13441 attctatttg gtatatgcct tatattatct ccactttttt tatctagatt tatagtatcg
    13501 ataatgtctt ttttcataat attatttgga ctagttctat ttttctctgg aaatacagcg
    13561 agaaaatatt aattattttc ttgctgtatt tttatattac ttaaaataga atttgtttaa
    13621 gttatctatt tgtggtaata tgttttttgt acaagctcag cgtacaattt tattagaaat
    13681 aggtgatttt ttggataaat ttaaatatgc ttttgataat aaaagatatc atacttggaa
    13741 ttactatctt agaaatactt ttggagaaaa agtttttaag gtatctataa atgcaggatt
    13801 tacttgccca aacattgatg gaagtcttgg ttatggcgga tgtacttatt gtagcaaaga
    13861 aggctcaggt gattttgctg gaaaccctaa agataatctt atcagtcaat tttataatat
    13921 aaaagaaatg atgttaaaaa aatggcctca tgcaaagtat attggctact ttcaagccta
    13981 tacaaatacg tatgctcctc ttgaagtttt aaaagaaaaa tatgagacta tattagaact
    14041 tgaagatgtc ataggtcttt caatatccac aagacctgac tgtttgccag atgatattgt
    14101 agaatacttg tctgaactaa ataaaagaac caatttatgg gttgaacttg gacttcaaac
    14161 aattcatgat tctacatcta aaattataaa tagaggtcat gattataaaa catttgttga
    14221 aggtgttgaa aaattaaagt ctaaaaatat aaaggttgtc gtacacatta taaatggtct
    14281 tcctggtgaa gattataata tgatgatgga aacagcaaag gcagttggta aaatgggtgt
    14341 agacggtata aaaatccatc tattgcatgt tataaaagat actcctatgg aaaagatgtt
    14401 acaaaatggt atgttaactc ttatggaaca agatgaatat atcaatcttg tctgtgacca
    14461 attagaaata cttcctgaaa ctatgataat ccatagactc actggtgatg gtaagaggga
    14521 tgaactagta ggtcctatat ggagcctaaa aaaatgggaa attttaaata aaattgatga
    14581 tactttaaag gctagaaatt cttatcaggg ctgtaagttt gtttaataca aaataataac
    14641 tatagaaatg gttatataaa tatagtcctt tctatagtta tttagtattt acaaaacaaa
    14701 atattaattt gtacatttat acaatatata ataaaaaata gatagtctaa actgtatcta
    14761 cttatatttt atttgtactg tccactttat tctataaaat ttgtaaatag ttatttttta
    14821 ataccaaata taatttggta taatttttgt tggactctaa aatgtatacc aataaatcct
    14881 ttttaagtat ataattctaa atactttcag ttttttcaat ctgctttaac ttgttggact
    14941 tataaaatat tcttatttca tcataagaaa gattaagtgc tactactgca gatattaaca
    15001 tcaacatcac tccaaataac ttccctaagg aaaaactttc tcctaatata gtgcaaccaa
    15061 ttattactga accaactaat tctactgatg ccacaacacc tgcaactgac aactctacac
    15121 ctttagatat acctgctgca taaaaaatat atgcaagtgc agctggaaca atgcctaaca
    15181 ttagcataca agataaaaca tctaaatcct tagcataatt taagatttcc caaggtcttg
    15241 aagaaggaat cataaatata gctccaaata agaaactgta tactaatatt gttgaacttg
    15301 aaaattcctt taaagcattt ttactaatag ttggcataag tgcatatgct attgctgata
    15361 ataccccaag taaaagccca aaagcgttta aaccttgaaa atccaaacgt ccaccagtca
    15421 ctgccataat tgcaccaata aaacaaagaa taagtgaaaa taatttgctt ctagtaatat
    15481 tttctttata acataatttt gaaaatattg ctaaaaacag tggtgatgta tatagtaaaa
    15541 ctgctgcaat tgatacaccc gcaatgtcaa ttgctttaaa ataacataaa ttaaacattg
    15601 cctgacatat aattcctatt attactgaat atataattcc ttttttgttt atctttaaga
    15661 tttgtggtgt ccttatagat gaatatacgc ctaaaactat aaatccaaaa aacaatcttg
    15721 taaatgctac ttgttctgat gtcagtccat ttcccattaa aaactttcca aataatccaa
    15781 gtgtagccca taataaccct gctattgcta taaatacata ccctttactt ttttctccca
    15841 ttttaaattc ccttctattt ttatttagtc aatttacact cttcttttta agcaaaaact
    15901 atgccatctt aaatcaatat atatcgactc taaaacccta gtctttccaa taatactaat
    15961 aaattttcaa tttttttata tttatttttc gcttacttta agttgattta gacttatttt
    16021 aattgtaaaa tgagttatat ataacttatt taaagttaaa atagactgaa acttatatat
    16081 aaatatcaaa ttttaagtat attaatcaat taaacctatt ttaatatatc attaaaaatt
    16141 taggaggaaa atataaaaat gaatttagat ttggaatttt atcaaaaaat attagaagct
    16201 tcccatgatg aaatatgtgt ttctgatgat aaaggaataa taatatattg taataaagca
    16261 tttgaagaaa attatggtct aaaaaaagaa gatattttgg gaaaaaatgt ttctttttta
    16321 gaagactctg gatattcaac aaaaagcccc ataccaattg tattaaaaac aaagactaaa
    16381 ttttcactgg aacaagatac tcaaacaggg aaaaagctta tcataactgc tacccctata
    16441 tttgatgaaa atggacactt agaatttact gttgaaaatt gtagagatat aactgaactt
    16501 aataatataa aaaataaact tgaagacaca aaaaagcaag taaaaaaata taaatctgaa
    16561 gtagaaacac tatacagaac tgcacttaga attgaagata ctgtaattat ggacggaata
    16621 gttatgagac caatcataaa cacagtaaat catgtttcta aaacggatgt aagtgtactt
    16681 ttattgggtg aatctggaac aggaaaaagc tcacttgcta gatatataca ccacaacagc
    16741 aatagatcta atggcccatt tataacaata aattgtgcaa ctatatctcc acaacttctt
    16801 gaatctgaac tttttggata tacttcaggt gcttttacag gtgcaagtac taaaggtaaa
    16861 gttgggctcg tagaattagc taatggagga actctttttt tagatgaaat aggagatata
    16921 ccacaaaatc tacaggcaaa atttttgcaa ttaatacagg atagaacttt tactccagtt
    16981 gggagcttaa aaaataaaaa ggtcgatata aggattatat ctgctacaaa tgttgattta
    17041 gtttcaaaag taaaagaaaa aaagtttaga gaagatttat actatagatt aaatgttata
    17101 gaaataaaat tgcctcctct tagagaaaga agggataatc tagtggaaat tataaaatat
    17161 tattttaata ggtactcaag tgacttcaac ctaaataaaa ctatttctaa ggaagctatg
    17221 gatgctattg caaattatag attcccaggc aatataagag aattacaaaa tataattcaa
    17281 aaaatcttgc ttacttgtac agataatcat ataacaatag atgacttacc aaacattctt
    17341 acaaaaaata tacatattac caataatgga aataaaacac atatatccca aattaataag
    17401 gttattatat ctgactcaaa atctactaat tataaaaata aaaattttga cactttaatt
    17461 aaagagtatg aaaaaaatat aattttggat gcttatgaaa aatttggtag ttcttataaa
    17521 gtagccaaac accttgaaat ctcacagtct aaagccaata ggttaattag aaagtatact
    17581 aatacttaat tttaaatttg ataaataaaa acttaacact atttacatat tgtaaatttg
    17641 gccatttact gttattatga atatggttga aattatttaa ataaatactg ttgacttagt
    17701 ttcatatatt taccattaaa cttttatcat aaatatcata tcataataat atatttaata
    17761 agtctaataa actatacgag gtgtaaatat gttaatgaat acccatttta ttatggcaaa
    17821 atcaatactt gataatatag atgaaaataa aacattcttt ataagcgaaa aaaattttat
    17881 atatggcaat ataaagcctg atgctttttc taaatataaa ttaaaaaaac attatttaga
    17941 tgagtcattt aatatgattg tttctaaaat aaactatcta tgcagtctta atatagatag
    18001 tctttctaaa tacttttcag taagtagact tagtcaggaa ctaggagtca tatgtcattt
    18061 tttatgtgat tttttctgtg tagctcacag tgaacgttgg gagtttaagc atagcttaaa
    18121 taaacatgtt acttatgaaa gagaacttgg agcatttgca aaagatgttg atttatctaa
    18181 aattaaatgt ggtactataa atagtagttt tgagaagttt tttactaaac tttatagcga
    18241 ttacaaaaag aaaactgatt atatgaatga tttaaaattt tcagcttata cttgtaatag
    18301 tgtcataaat tatatacttg actctatttt atctaataca ataaaatcat atcatatagc
    18361 aaattgcggt taacttaaga atttttaaac ttatataaac ttataattga atataattaa
    18421 aatgactgct ctatagaata taattttata cttctctagg acagtcattt tttatactaa
    18481 ctatttatct ccattataac atctatggca ctttttacac tatctactac ataatttgca
    18541 ctttgcttta catcttccct tgccttagac attgcaaaac tatatttaaa tccttctaac
    18601 atgcaaatat catttggaga atccccaata gtagcaactt catctggact tacatttaac
    18661 gtttttatta catgctctat acttcctctt tttgacacac ttttaggaac tatatttaaa
    18721 gtatatgttc cagaaaaata tatttctaag acttcactaa actcactttt tagataaagt
    18781 tctattctgg ataactcttc caaattttca gaacatacgc ctatatttcc tataagatta
    18841 tcaaaactac ttcttttttc aaaatctggg tcaactataa agtcactaga ataatgtcta
    18901 aaagcagtgg tatcactacc cacaattaca tcacccttat atttaaaata aagttgtgca
    18961 tcacttgact caaatctatc aatgactttt tttactaaat tatcatctat cgttctttta
    19021 aaaattacat tataatcttt atcatatata aatgaaccat tttcacatac atagtatcca
    19081 ttcatatcta aactatcttt gataatatta tgtgcttgtt taaaaattct acctgtagca
    19141 acattaaact gtactccctt tttttctatt tcttcaattg ctactatatc ttcttttgtt
    19201 atggttccat tttcatatag agttccatct aaatcacaaa atatatgttt tatcataaat
    19261 taaaagcctc caaaaacaat tttatatttt actaatactt taatcaaaat aacttaaagc
    19321 ttttctaatt gtattctcaa ttcattaagc aaatctctag tagctcttaa tcttatcttt
    19381 cttctatccc cattaaatat atttttcttt actattgttt ttccatttat atatattgca
    19441 gtataaacca gtcccacagg cttctctttg gttcctccac caggtccagc tactccagtt
    19501 gtagatatac ctatattagc tttaagtcct ttagcaacgc cctcagccat ttctatagct
    19561 gtttgctcac ttactgctcc aaactcttcc aaagtttctc tttttactcc taatcttttc
    19621 attttagaat cattagaata tgttacacaa ccttcaagaa atacagagga tatacctgga
    19681 tagtttataa gagatgaaga aaccaaacct ccagtacaag attcagccac tgctattgtt
    19741 agattttttt ctacaagtag cttagaaaca gcatcttcta aagcagtctc accttcagat
    19801 atggaaatat ctccttcagt atatacatat ttaccaactc tactttttat tttttcttct
    19861 actgacttta ttaatttaaa agcttctctt tcattttcag cctttgcagt tattcttatt
    19921 gtaacttcta attcttttgc atataaagca actgttggat tagtctgctc attaattata
    19981 tcgagaattt ctaattctag atttgactca cctattccat ataatcttaa agtcttagat
    20041 actagcattt catttgtgaa ttgttgtaag taaggtttga cactctcatt aaacatagct
    20101 ttcatttctc ttggaggtcc aggcaatact attataaatt taccatcttt ttttaaaatt
    20161 gcccctggag ctgtaccatt attatttttt agtactatag catcttttgg aaagtacact
    20221 tgtttcatat tattttcggc catttttttc cctgttttaa caaagaaaga ttccaaaacc
    20281 tctagtgaag gtttatgtag ttctaatttc tgaccaaagt attctgcagc agtttctttt
    20341 gtcatatcat caccagttgg cccaagacca cctgtagtaa ttacaaaatc acttctcttt
    20401 aagctttcat caaaacattc taaaagtctt tgtttgttat ctccaacagt actctgatgg
    20461 tatacttcta ttcccaatga tgcaagttct ttagctaaaa attgagaatt tgtatttact
    20521 atatctccca ataatatttc tgttcctaca cttattattt cagctttcaa aatttatcac
    20581 tccttgattt atagccatta agactagtct taagttcata acaataattt tagcaaaaat
    20641 aataacataa ataaagttaa aaaatcattt aaacatatct ttaaactaga ttattattct
    20701 aaaaccacac ataatataaa cttcgtatat agtggtactt tcatcctcaa ctgttaattc
    20761 atataattaa gtatgtaaat aaaaagttta ctttaaaata ataaaaatta aaataggagt
    20821 gtataatatg aaaatagcag ttataatggg tggaatatca tcagagagag aagtttcttt
    20881 aaattcagga aaagagatat ataataacct tgataaaaat aaatatgaag ttgtaaaagt
    20941 aataatagat gataaaaaag atatatttac aaagatacca gaagatatag attttgcaat
    21001 acttgcttta catggaaaat ttggtgaaga tggatgtata caatcaatac ttgagactat
    21061 ggatatacca tactctggat gtggacctct ttgcagtggg atgtgtatgg ataaaaatat
    21121 aactaaaaaa atgcttagag attcaaacct acctactgct ccatgggttt tagtaaaatc
    21181 agttgatgaa atagactatg atgaaataga taatataggt tatccagtat ttataaaacc
    21241 aaactcagga ggttcaagtg tagccacatt ctttattcat tctaaggatg aagttgaaga
    21301 agcagttaga aaaggtctgg aagttgatga atttgtaatg attgaaaaat atataccagg
    21361 tggagaatat acttcattca tattaaatgg agaagtgttc cctacaatat ctataaaatc
    21421 tgattcagga ttctttgatt atgaagctaa atactcagtt gaaaaaggtg caaaggaaga
    21481 agttgtttac ttagatgaag aacttcaaaa aagagtaaac gaaatttctg agacttgttg
    21541 gaaaattttt aattgcaaag catatgtaag agttgatatg attataagtg aaggtattcc
    21601 atatgttctt gaactaaata ctcttcctgg aatgactcaa actagtttaa ttcctagaag
    21661 tgctgctgct agaggtatta agtacagtga actattagat aaacttatag aatactcttt
    21721 aaattagatg aaacaatttg aggtggtaat ttgatatttt caaatctaaa attaaatgat
    21781 aatgaaccaa tttatataca acttaaaaat tatataagtg atatgatatc aaaaggacta
    21841 attccagaca atagtaagct cccttctaca agggagctta gtcagctttt acaagttagc
    21901 cgaaattctg tagttttaac ttatgaagaa ttaaaatcag aaggattaat ctactctatt
    21961 tcaggaaaag gtacatttgt taaatcaaag aataagtctt caaatactac atggtcatta
    22021 aactgggatt gtttagagaa tacatactct aaaaaagcca atgaattaga cattataaaa
    22081 agtgaaattc cttggagctc tgacctaatt tcctttaaaa gtatttctcc agatggagat
    22141 ttattcgaca tggaagaatt aaaaaaatcc tttttaaata gaatttcact agaaggacat
    22201 aaattactca actatggata tgcacaaggt tataggcccc ttattgacta tttactagaa
    22261 tatatgacaa acaagggtgt tgatataagt aataaagata tactaataac aaatggattc
    22321 acagaaggct ttgatattat tatgtcatct tttacccaag aaaaagacta cataatatgt
    22381 gaaaatccta ctcataatac tgctataaaa attatgaaat ctcataacct caatatctta
    22441 ggtgtagata taaatgaaga tggtttggac ttcaatatgc tagaagacaa tttagttaag
    22501 tataaaaata aaataaagtt tgcatacatt acaccctctt atcacaatcc tacaggaatt
    22561 gtaatgactc ctgaaaatag gtacaaattc tataatctta tgaaaaaata caatatagca
    22621 attatagaag atggatttaa tgaagaatta ctctacaata gttctcatat atttcctatc
    22681 tgttccctag ataatatgaa taatggggtc gtatatattg gtagtttttc aaaaatttta
    22741 tttcctggaa tgagaattgg atggatattt gcagataaaa aagtaatcaa taagctagaa
    22801 agtgtaaaaa ggtgcagaaa catacatgta tcctttttag accaaggaat tttatttgat
    22861 tacttaagta atggaggttt tgaaaaatac attaaaaaaa tacgtaaatt ctatggagac
    22921 aaatttaact ttgcatataa atgtataaaa aaatatataa aaacagaata catcttgggt
    22981 gatggtggtt tgcatatatt tataaaacta aaaaatatag atactagagt tttattagaa
    23041 aaatgttatg aaaaaaatgt tatatttatg cctggagatt tattttttac agataactct
    23101 ggttttgata ctttaagact tggattttct aggttgtctt ttgaagacat tgaaattgga
    23161 ataaaaataa ttggagaaac tataaatgaa atgttctagg ttaactaaat attgttagcc
    23221 tagtttattt ttatgaggta taatatatat agtttatatg aatctaatac tgggggataa
    23281 tatgagtaaa aagtcaaaac gaagaaaaat taataaatta aaattaacga ttgtaataac
    23341 tgtattattt cttgctttat tatctatata tgagatactg ttctctaatc ccaacaaaaa
    23401 aggtaatata aagagtcaag aaactatgca aaataaaaat aatacaacag atgattctaa
    23461 aaataatcaa agctctacca aaaagcagga agataataat atcaagccta ctttttcata
    23521 ttcttcaata ccagataata taaaaaataa aatgattggt aaatctatgc ctactgatga
    23581 acctataagc tttgataatc tatcttattt aaaacttaca tattatggat ttgatgaaaa
    23641 aactcatcaa ggagaaatga tagtaaacag tgaactagct ccagaagtag tggatatttt
    23701 taaggaatta tacgaaaaaa aatatccaat tgaaaaaatt aagttaatag atgactatga
    23761 tgctgtagat gaaaaatcta tgtctgataa taatacctca tcattttgtt atagaactat
    23821 agctggtaca aatgtcgttt caaatcatgg taaaggacgt gctatagata taaacccttt
    23881 acagaatcct caagtttctg gaaatgatgt tacacctaaa gtaagtacag tttatgctga
    23941 taggtctagc acaaaatttg gaatgataaa aaaaggtgat gattgttata atgcttttgt
    24001 aagcagaggt tggagttggg gtggctattg gaaaaaccca gattatcaac attttgaaaa
    24061 ataatagatt agaaataaag gtgaattata tgaatttaat gacattggaa aatataagta
    24121 aaagctattc tgaaaaaaaa ttacttgaaa atatatctct tggaataaat gagggggaaa
    24181 aaataggact tattggtgta aatggtactg gtaaatctac cttactcaaa attattgcag
    24241 gagttgaaga aagtgagact ggtaatataa caaaaactaa tggtattagg atagaatatc
    24301 tacctcaaaa tccaacttac aatgaaaatt caactgtact tgaacaagta tttaatggaa
    24361 cttctgaaga attaaagcta cttggtgaat atcaagaaat cctagaaaaa cttaattcaa
    24421 actttacaga ggaattaaat aaaaaattat tatcagtaca cgaaaaaata gatgccttaa
    24481 atctttggga tttagaaagt gaagctaaat cagtacttac aaagcttggt ataaatgact
    24541 ttaatcaaaa aatagcagaa ctttctggtg ggcaaagaaa gagagtctct ctggcatcag
    24601 ctcttattac accttgtgag tttttgatac tagatgagcc tacaaaccat ctagacaatg
    24661 atactataga ttggcttgaa gaatatctta attcaagaaa aggttcattg cttatgataa
    24721 ctcatgatag atacttttta gaccgtgtta caaatagaat tattgaactg gacaagggta
    24781 gattattcag ttatgatggg aattattcaa tatttttgga aaagaaaatg gaaagacttt
    24841 cgctagaagc aagtattgaa gacaaaagac aaaatttaat aagaacagag cttgcgtggg
    24901 taagacgagg agctcaggct cgtagcacta aacaaaaagc tcgtttacaa agatttgatg
    24961 aacttataaa taaagactct tttaaacctg atgaaaatct cgatatatct gttgcatcaa
    25021 gcagacttgg aaataaaata atagaaatac acaatatatc taaatcattt gaagaaaata
    25081 ctgttataga taatttagaa tatactttaa ctcgtacaga tagaattggt ataataggca
    25141 aaaatggtat gggtaaatct acccttataa acatacttaa tggagaaata gagcctgata
    25201 gtggatatat ttcaattgga gaaacggtta aaataggttg tttttctcaa gacgactctc
    25261 atatgaatat tgatatgagg tctatagact atgtaaaaga agctagtgac tatatagaaa
    25321 cttcagatgg tactaggatt acagcttctc aaatgtgtga aagattcctt tttaatggta
    25381 ctatgcaata tactttgata ggtaaattat ctggtggtga aagaagaaga ctacatcttc
    25441 ttaaaatcct tatgacagct cctaatgtgc ttcttttaga tgagcctaca aatgatttag
    25501 atattgaaac tcttaaaata ttagaagaat acctagacga atttaaaggt gtagtagtta
    25561 cagtatcaca tgatagatat ttcttagata gaatttgtaa taaaatattt gcatatgaag
    25621 gtaatggaaa aattcatatc tatacaggta attacagtga ttatcttatt tatagagaga
    25681 ttcaaggaat tgaatttgaa gaatctaaaa gggaatcagt taaaaaagat gactctacta
    25741 ccccaaaaaa agaaaaacct aaaaatgata aaaagcttaa gttctcatat aatgaacaaa
    25801 gggagtttga aaatattgac tctgatatag aaaaactcga atctaaaatt gcaacacttg
    25861 atgaaagtac ttcaaaattt tcaactgatt ttactaaact tcaagaaatt ttagatgaga
    25921 aatctaaact agaaaaagaa cttgaataca aatatgaaag atgggaatat ttaaataatc
    25981 tagctgatga aatagctaat aataaatgat attaaaataa tcttaagttt aataagtttt
    26041 gctttaaatc tgtactttat aaatatttta aagggagtgt ctcaaaatga actttttagt
    26101 tttatgagac actctttttt atgtgaaatc aaatatattt tcatcatttc aacaatacaa
    26161 aagaggctta tctctatttt gagacagcct ctttcataat ttttataatt accttctaat
    26221 ttatatgctc taatatatct ataataattc ttattatatc tatatatcca gtctttcaat
    26281 atagtgacaa ttaacttcaa tatgatttaa aaatactaac aacctttcat aaagtggatg
    26341 agattcttct ccatatttag cttctaggtt cttgcctatt tctctaacag tcctttgacc
    26401 atcaatttgt aaaaaaacaa aactggaata ttcatctagt tctatttttt tgtatttagg
    26461 tattctagct tttaacttcc taaaaaactt ttgaatttta tggtcctgtt tttcaagtat
    26521 agtaacaaca ctattttcag ctacttcata ttcaagtcca tcagtaattt taaatacaat
    26581 atctaaaaca tcattactct tgctcattat tttttacttt agataaaaca ataggtaatg
    26641 ctgtaagtac aactaaaact actaataaag caattgccat tgaatttgtt gcagcaaatc
    26701 cacttggtac ctttggagtt acaactccag ttacttgtaa tattatacct attaaaccaa
    26761 tgatagaacc accagcaaca agaccagaag ataaacttat accattagaa actttaactt
    26821 ctttttcttt ttcagtttta gatactaatt caacaaataa acgaattaat gctccaacta
    26881 atattataga agttgttgca attggtaaat agaatcctat agctatagtc attattggta
    26941 aatttaatgc atatagaacg attgccataa atactccaac aataatcata acccaaggta
    27001 aactacctga cataatacca gaagttaatg ttgacattaa gtttgcttgt ggtaatgcaa
    27061 attgtatatt atcaccagtt gctctaagtt ggtcagaaag taataaaatt actcctacaa
    27121 caactataac accaactata cttgcaattg taaagtaacg ttgcatttcg tttttgctac
    27181 caccaataat ataagttact ttttgagatt gagtataacc tccagctata gcaatagcaa
    27241 caactataaa tgaaccaaat aaaagtaatg atttattagc ttctaaatca gtccatccca
    27301 ttataacaaa cactaatgtt acaataacta gagaagctat agtcatacca gaaactggaa
    27361 gatttgatgt tccgattgtt cctgttaaac gaccagctac tatgacaaat aataaagata
    27421 ataaaagaga tatgatagct ccaataattg ccatgacaat gttaccagaa attaagaatg
    27481 ctgctaaaaa tccaataact actccaccta ataaaagtat catttgtata gatgaacctt
    27541 cttctccttc tccagtgctt gatttagctt taagtgtttc ttttatagaa gcgattatag
    27601 ttggtataag ttttattgca ccaataatac ctccacaaag catcatacca gcacctatat
    27661 attttacata actactagat attgctccaa catccatttg gttaagaggc attgcaggat
    27721 tattccatac catagctcca tctttagcca tatctgtaaa gtatcctatt aaaggtgcta
    27781 taccaaagtt tgataaaata cttcctgcaa acattgttaa agaaacttca agccctacta
    27841 taaatccaat tcctaaaagt agaggattta cttcaatatc aaatttccat ttgtagaatt
    27901 tgcttcctac aagactcatt acattatttg ctacatttaa gaatgaacca gttaatacag
    27961 taataaatcc acttattaca aatccaattc ccatgtactt aattgaatct ccaccagcct
    28021 ctgaagcaac aagtgtctca gatatagcca ttgattctgg gtacataagt ttaccatgtt
    28081 cttcaactat tagatagttg tgaactatag cagcaattcc tataccaaat aaaactccac
    28141 caactccaac agctaagcct tctaagaatg taatttgact tccaattaat ataactgctg
    28201 gtaatacgaa aataaatcca cttgcaacag attctccacc acttgacata ccttggatta
    28261 agtttttacc aagaataccc tttgaacgag caaatgctcc aacaaaagca gaacctatta
    28321 tagctcctgg aatacctgcg gcaactgtaa gaccggcttt cattccagag taagttgtag
    28381 atgcggcaaa aatggcagct aaaataatac cgataatcag tacagctaca tttccaccgg
    28441 ttctggactt atctgtgata tatggaacgt aatcttttcc actaacctca ccataagcac
    28501 ccttaggtaa ttttttgttc ataaaatttt cacccctttt caatttgtat atattataac
    28561 atatatacat ataaaactta actttttatt attttacaaa tagcgagtca aaactactaa
    28621 aatttaaccc tatattatta atttctactt ttagatattt ttatgctaat tttcttttta
    28681 tttttcaatt ctactaaaaa ctattaagat ataaaataaa aaaatttttt aatgtaaaat
    28741 taattttgta aaaaaaatgc tttaaaacac ggaaaagtat aaaaaataca ataatcattc
    28801 ttataaataa attttcacca tagtaaatat atacagaaaa ttcttttttt tacatcaatt
    28861 gattttctca gaaaaatagg tgtcataaag aaatgtatgg aatcacttta caacacctgt
    28921 cataataaaa aatcactctg gtagtgcttt tttatttact tttcctattg gtgtaactgg
    28981 tattttatct atcctcatta ttattgttgg aatcatatat ggaggtagat gctcatttaa
    29041 atattctcta atagttcttt catttatctt accactatct tcctcatcaa ttacataata
    29101 tgcacatata tacatatccc catcatcatt tgttctcgat atacaaacaa cacttttaat
    29161 ttctgtaata ttatttatta tattttcaat ctcatatagc tctatcctaa actcatcaat
    29221 ttttacttga ttgtccatcc ttccaatata atctaaattt ccatcatcta accatcttac
    29281 taaatcacca gttctataca ttaacttatt atgttcacaa gttttgtaag gattctctac
    29341 aaatacttgc tctgttagcc cttttttatt taaatatcct cttgatattt gaatgcctga
    29401 tagacataac tctcctggag ctccaattgg acatagtttg ttctttttat ctaatacata
    29461 tgcataagta ttaaatatag gttttcctat tggtattttt ccatattctc tgtccacatg
    29521 aaaagaagtc gatacaacag taaattcggt tggtccatac tcattatata gttcataatt
    29581 acgctttcta tatcctttta atctttctcc tccagtctgt acaactctaa gtgaattatt
    29641 attgcaattt tgtataaata accttgcaaa cgctgttggc aatgctagta tagttatgtc
    29701 attttcctca caatattcat ttactgtata ttcatcaaat ttagcttctt caggcataat
    29761 atctattgat gcacctacaa gcaaataagg gaatagttgt ttcattacag catcaaaact
    29821 gaaacttaag tatataccac atatatcatt ttctgtagcg tttatagatt ttacgctata
    29881 ataacacata tttactaaac tcttatgttc tatagctatg gtctttggcc taccagttga
    29941 ccctgaggta gatatcgtat atgcacaatt tgatggtgtt attttttcag ttaattcata
    30001 tccaagctta aacatttctt catcatttat atcgagtact atggtattct catttacaac
    30061 cttacttttg agttcatctg tagttatcac tacttttgca ttactatctt caagaaggta
    30121 attcaatctt tcttctggat tacttgtgtc tattggaaaa aatgctcccc ctgatttcat
    30181 aatccctatt gctgtaataa ttatgttaat atctcttggt aacattacag ctactatgtc
    30241 ttcactttcc actcctatat gatttaaata acctgcaagt ttatcagtta cctcatccaa
    30301 ttctttatat gttaactttc tattttcatc cctagcagct atattactag gtgttacctt
    30361 aacttgctcc ctaaataaat caacataact tttatcatag ggtacttcat attgattatc
    30421 attaaagtct tccaataata ctttttcttc ttccttacat acaaattcta aatcttctat
    30481 taaaatatcg ttatcttcta ttatttgctc tattatataa tcaaattgat ttaaaattct
    30541 tctaatagtc tctcttttat atatagatgg tttatacttt atttttattt taagtgccct
    30601 cttagtatat actattacag ataaatcata tccttttttt tctatgtcat aatcatatga
    30661 taaatcaaaa cttttagcta taaatattgt gtttataagc ttagtattta gatgattttt
    30721 attctctata tctgataaca aatagtatcc atactctaaa gacctgctcc actgcctttt
    30781 tagcttcctt acaacatcta taaatttttc actttgtcta actcttactc ttattggaat
    30841 tatattcatt gttttaccaa aaactacatc atcttcatat atatactttt gaagtataag
    30901 accatatata gtttctatga tagagtctat gctaatattg ttcactttag aatattgaat
    30961 taacctttca tgtttctcaa tattcatctt aaaaacctca tctactactt cgtcagaaca
    31021 atctttataa aaaaaatcat ttggaatttt tgctatattc gtataatcat ctaacaaatc
    31081 catccaataa ttcatagctc gttctaaatt aacttcatac atatcaaaat tcccccttac
    31141 tactaagtct atagaaaaaa ttcttttgga attttatttt cacaatatat aaatatatta
    31201 ataatacata tgcaagctct aaaaacatga gcttgcataa aattacacct attattatgg
    31261 ctactaaatt cgtaatattt ataatgttta aaatatatta taacacatat atgattttat
    31321 ttttctacat ttatataata tataaattac aaatagttat ttaattaata tataacaata
    31381 ccttttggaa tatgatatat tatattaatt aaatttttat aagataagtt atatttatcg
    31441 aaaggggcca cataaatgaa tatttatgct catagggggt ttagtggaaa gtatccagaa
    31501 aatactattc tagcttttaa aaaatgtttg gatatggata tatatggaat agaacttgat
    31561 gtccacagaa ctaaggatgg aaaaattgta gttattcatg atgaaaaggt tgatagaact
    31621 tttaatggac atggttttgt aaaagacttt actttaagaa aattaaagac tctaaactca
    31681 tcttttgaag gatatcaaaa caataaagaa tgtaaaattc caactttaga agaagtatta
    31741 attctaattt cacctacaga ccttatttta aatatagaac taaaaactga caaagtaaac
    31801 tatcccaata tagaaaaaga tgttttagaa cttattttaa agtataatat gaaaaataga
    31861 gttcttatat ctagtttcaa cagcaatagt ttaaaaaact ttcataaatt agaccctagt
    31921 gtaaaaacag gattattgtg ttatttacct ataaacaatg tagtcaattt tgctaaattt
    31981 ctgggtaata gttaccttca tccacctcta gttttagtaa atgaatctct aattgaactt
    32041 tgtcacaaaa atctacttgg tgtcaatgta tatactgtaa atgaagagga tgatatacta
    32101 cactgtctaa agctcaatgt agatggtatt tttactaact atccagatat tgcttcaaat
    32161 cttttacact caaaacaata tcgctaatta cacaatattt tgtactcctt gacttttata
    32221 taattaatat gtacaatttt attaaattta tcttggaggt ataactatgg ataacttatt
    32281 aaatgaactt gaagctttaa agagtaattt agataatcta ccaatagaaa aaatagaaaa
    32341 ttatgatttg agtaaaactg ctttatttat aattgatgtt aataatggct ttgcaaaaca
    32401 aggtgcatta tactctccta gagtagagtc tttaataaaa ccaattgaaa tgtttacaaa
    32461 aaaaatatca aacaaattaa atagagtaat agcatttact gattctcata ctcctaagtc
    32521 aatagaactt ttgagttatc ctgttcactg tttggaaaat gatgtagaaa gtgaattggt
    32581 tgatgaactt aagtcgatag aaaacctaca aatttttcct aaaaattcta ctaatggatt
    32641 ttttgcatta gaaaatttgg attttgataa tatagataat ataattatag ttggcgattg
    32701 cacagatata tgtatatatc aatttgcaat aactctaaaa tcatatttta atcaacataa
    32761 tattgaaaaa aatatagttg tacctatgaa tttagtagat acttatgata ttcctaacgt
    32821 tcaccctgct gagattttaa acttagtatt tttcaacagt atgattcaaa atggagttaa
    32881 tgtattaaaa gagattcgtt aatcctctaa tactttacat cccatatata caattatcag
    32941 atatttattt ttaataaaat ctctactaga aaaacacagt tttagtgaga agattacaat
    33001 ttaaaacatt atctattatg actaatcttc acaatataaa aaatcgcagt ttagatattc
    33061 cttatacaaa tttataagga ataataaatt gcgattttta tttttaagta atacaattaa
    33121 tcgatactac ttcagtattt aaattcattt tttaataatc atacttattc gtagtttcgc
    33181 acattactac ctttattttt ttattaaaca tattcttata ttctaataaa aactcattta
    33241 gttctgaatc cataagattt atttttctat cactacaaag cattatcttt tcttggtcga
    33301 ttattacatt aatatcattt aagtcatttt ttataaatgt tgttatacaa ctctttggtt
    33361 ggattttttc tccatatttc tcataaaatc ctgcactctt cttaaatgac tctaaatctt
    33421 ctgtagatac tttgctggaa gtattattac tcataaaacc tgctgtagaa gggtcgattc
    33481 caaagtttct aagttgtttt tctacttctt cagtgtccat accatatctc tccataaatt
    33541 gcttttgtat tttcataaat ttttcttgag atatgttgtt atctctcata taatcgaata
    33601 tttttcttga aaactcagcc atagacatct ttccatccat aacagaaaaa tataagttat
    33661 atatgtattg ctcaaattta tctacatcag aatctttaac tttgttcttt agttcgttaa
    33721 agtctattat tctatcatca gacatttttc atcctcctag ctaaattttt acttgtataa
    33781 gattatacca tatttctatt atatttatat acacactatt tttttaattt aacgattttt
    33841 tctgtagcat ctaattcgca cattctgccc aaaggaatag ttatcattgg gatacaatgt
    33901 cctgactgaa gattatatat agaaggttta ttgaccttat ttgcaaattc tattagtaat
    33961 tctattaaat cattttcttc aatacaatcc ttaaaatctc caaaaattat accattacat
    34021 tcctcaagtt ttcctgaaga atatagttgt gttaacattc tatccagttt atattgaggt
    34081 tctccaattt cttcaataaa caaaatttta tcttttgcat ctatttcata ttttgttccc
    34141 attgtggcaa ttattaagga taaatttcct cccattatta ttccctctgc tttaccttca
    34201 catacagtat aaatcttttc ttcttttgga ttttctaaat ataagtaatc tttaaattct
    34261 aaagcattta ccaatgattt ataggtaaat tcatcccatt tacctatatt tgctgccatt
    34321 attccatgat atggtaaaag gccacaattt ttataaaaag ctaaatttaa acctgttata
    34381 tcagaaaaac ctataaatgg ttttggattt tgttttatta tatcataatt tattttatcc
    34441 aatattcttg ttgttccata acctcctctt aagcacataa ttatatctac atctttatct
    34501 aaaaacatat cttctatatc tcttgctcta atatcatcat taccagctaa ataaccttta
    34561 taatttaaac tacaactttc agaaaactta acttcgtaac cataactttc taaattaaac
    34621 tttatttcct ccaaacttgt atttcttaat ggcccagatg gcgcaattat tcctaacatt
    34681 taaacacctc ttcttataaa atgatatatt cttctccata ctaaatatct ctaatataat
    34741 tataagatat tttatttgta cttgatacat aataatgatt tacataaaat aatataatta
    34801 atgaagaaaa ataaattttt aatatagtta ggatgtgttt tatgcttaat ataagaactc
    34861 tttgtcatga gataaatgat tgggttataa atataagaag agatttacat aagactccag
    34921 aacttggatt agaagaattt caaactaaga aaaaaattat taaatactta aatgaaatag
    34981 gtataaatta tattgaatat aagaatcata cagggataac tgcatacatt aacgtgagtc
    35041 caaactttga aacagttgct ataagagctg atatagatgc cttacctata acagaagaac
    35101 ttaattattc ttataaatct attaatattg gtaaaatgca tgcatgtggt catgatgcac
    35161 acactgctat tttactgggt acttgtaata tactatttaa attaaaggat tacttaaatg
    35221 taaacgtaaa attctttttt caacctgctg aggaaactat tggtggggct caacttatga
    35281 tagaagatgg atgtcttgaa aacccaaatg taaaatatat atttggactt catgtaaatc
    35341 ccaatatcaa caaaaatcta attgaattaa aatacaacac tctaaatgct tccactgata
    35401 cacttcaatt aactgtacat ggttcaaaat gtcatggagc ttatccacat caaggtattg
    35461 atgctatcgt tatatctgct catattatta cagctctaca gacaatcgtt agtcgaaaca
    35521 caaatccaac tgattctgtg gttatttctc taggaaagat tgaaggtgga atcaaagaaa
    35581 atatagtttg tgacaaagtg gttataaggg gtactttgag aaccttaact cctgaaacta
    35641 gagaattttc aaaaaaacga attagagaaa tttgtgattt tacttgtaaa acatttggag
    35701 gaagtgtttc tgttgaaatt gatgaaggtt atccagctct tatcaattca aactatctag
    35761 tagattacgt caagcaaaat gctgtagaat tgtttggaga agaaaatatt atccttaaag
    35821 acgcacccac tcttggggct gaagactttt cgtattttct aagacattgt gaaggagttt
    35881 tttaccacct tggttgtgca aatcgagaaa aaaacattac ttcccctctg catacctcta
    35941 cttttgatat tgacgaagat tgtcttatta ctggtgtcat gcttcatgta aaaaatgtat
    36001 tagcatttta aatattaata tttttattta ttattttata ttgaccctca catgatgtca
    36061 tgttataccc taaaattaca aatgataaat taaataattg gaggtaatat tatgaaagaa
    36121 atattaataa atcctatagg taaaatacgt attcaaggcg aagaggtctt tattaaatta
    36181 gacaaaaagt atgtacctgc attaaatgaa ctcgacgatt tcagccattt aaatgtattt
    36241 tggtgggctg atgggttcga taatcctgaa ctaagaagta ttttagaaac cccaaaacct
    36301 tataaaagtg gaccagatgt tataggaata tttgcaacaa ggtcacctat aagacccaac
    36361 ccaatagcat tgactactgt acaaattatc aatatcgacc atgaaaatgg tataataaaa
    36421 ataccatata ttgatgctaa tgataatagt cctgttattg acttaaagcc atatactcca
    36481 agcgttgata gggttgaaaa tccgtcagtt cctaaatggt gtagtcactg gcctaagagt
    36541 gtagaaaaat caggagaatt taattgggaa gatgaaattg aattttaaat tacttttttc
    36601 ttgatttcat taacttgttt tccacattta ttttatttac acttaccaag attttatgtc
    36661 acatatacat ataatattag gctgtattat ataatacagc ctaatattat ataataaatt
    36721 tctatttttc ccttaaacca ttcacattct ttctaagcta cataagattt ttctattatt
    36781 tctttttgag tttaatttag cattatgttg aggaaaaaac atttcatgca tttttaataa
    36841 attaaatttt tcttttattc tacgatttta taataatcaa tttaacttaa aaataatacc
    36901 taactatttt aactatgtta aactagtaaa tgtaaccact tatatgttac aattttatat
    36961 aaacatcaga tataaaaaac tatataaata aatgacgcat agtgttatat tttttaatac
    37021 caatttagtt atttttcagt tacagattta ataataatta atagtaagac ataatatttt
    37081 tatgcccttt attgattatg tattttctgt tattatcatc aataataaac ataagggggt
    37141 atatattatg aaattgtatt taagtgctga tatagaaggt acttgtggta ttgtaaattg
    37201 ggatgagaca aaacttgaat gtgaattttc acaacactat agaacacaaa tgagtaaaga
    37261 gataacagca gcatgtgatg gagctactca atccggtgtg catgagatac ttgttaaaga
    37321 tgcacatgac agtggtagaa atattaatcc aaatatttta cctgaaaacg tcaaaatact
    37381 tagaggatgg accaaagacc cactagttat gatggctgga attgatgaaa gctttgatgc
    37441 atgtatattc actggctatc actctggagc tacttgtaat ggtaatccac tttctcatac
    37501 catggatatt gattatgact attttaaaat aaatgatgaa atagcatctg aatttactat
    37561 aaatgcttat attgctgcat attataatgt tcctgtagca tttttaagtg gagatgaaat
    37621 gctttgtgag agtgcaaaaa aactaaatcc aaatatagtc actgttcctg tgtcaaaagg
    37681 aattggaaat ggttcaattt caatccatcc aaaccttgca ctaaaaaaaa ttgaaaaagg
    37741 tgtcaaaaaa gctttatctg gagatttatc taggcactta ataaaattgc cagataaatt
    37801 taagatagaa ataaaattta gagaacatta taaagctttt aaggcctctt tttatccaaa
    37861 tatgaaaaaa atagattctc aaacagtact atttgaaaca gaggactatt atgaattttt
    37921 aagaatgtta ttatttatat aaatttcata tcataaatta aggagttgat taagataagt
    37981 aataaaagaa ggattccttt aggcgaattt atttatgtat ttttattttt tgctgttttt
    38041 tttggtataa ctttttgtat tttcacggtt ataggaattg gcttcttatc attcttagga
    38101 tttgaatata aatctcttgg agctgtatta attttctttt taatatattt ttgtataacc
    38161 actccaattg attttctatg cactactatt ttagatatat tcagatatgt aaacaaatta
    38221 ccatactcaa tatataaact ttgcgaattt ataattgatt ttatactaac ttttctagct
    38281 atgaacataa ttgatacctt tatggattca gtaacgattc ctttaagtac agaaatctta
    38341 ttcgctttac tttcttatct tttatcagaa tgtatggatt tttttgatag ggataagaaa
    38401 aaaccttaat aaaaaagata gatttcttaa tagaacacat attttcgtat ttctattatt
    38461 taatctatct ttattttatt taataaattt ttattaatta aaatatagtt tcttctatct
    38521 ccttagtcat ttgcttagca ctatcaaaaa attcttctat atacactact tcatcactga
    38581 ccctagaata ttctgctgca aatgccatta catgactttg tatagcttct tttgctgcta
    38641 ctctaccctt ttctagttct ttatttgaaa ctaatttaat aaattcagct ataagatttc
    38701 tatcatattc ctctaccata ttctgttgat ttgatggatt cataactatt tcttcgtttt
    38761 ttccaaattt tttaattctt atctcatttt tatttaaatc tccaccaact tcaccatggc
    38821 taaacattaa ctttatagtt cttccatttt ctttagtaaa tgcacataaa ttaaaagtag
    38881 ccgtcactcc attttcaaac tgtagtatat ttaccatatt atctacaaca ttattgtcac
    38941 atctataaac acatcttcca tatggacttg tcttaagtat atttaataga ttctcttcag
    39001 ttggatttat gtgaacagct ctatttatac ttctatcttt ttctaaataa attctctttg
    39061 ctgaatatgg acattttttt tcaactaaac actgaagaca attttgtgcc atctctccac
    39121 tagcattttg gttattcaga tgctttaagc ttccaaatgc agatattttt ttgcatctac
    39181 ttcctactaa atataacaaa atatccatat catgacaact ctttgctaaa attaaaggac
    39241 ttgtttcatt gctatttctc caattccctc tagcaaagct atgtgcaaaa tgccaatatc
    39301 ctatattttc attatattgt atactaacta gctctcctaa ttttttgctt tctacaattt
    39361 cttttaattt attataaaat ggagaatatc tcagtacatg gcaaatcata aaaatcttat
    39421 ctttatactt atcacacaag tcatctatat gtaccagacc atctaaacta ttagacattg
    39481 gcttttctaa tagtacatga taaccttttt caagagctag ttttgctaca tcataatgtc
    39541 tatcatcatt tgtagctatt attactgcat ctgccatctt gtcatgttta aaaaagtctt
    39601 ctaaagtttc aaatacattt ttactatcta ggttatattt ttgtgtaaat agttctcgtc
    39661 ttcctttttt aggttctgct acagcaacta tttcacacac atcagaattt tcataaatat
    39721 atggagcata tgcatacgtt cctctattac ctgctccaat cacagcaact ttcacttttt
    39781 ccatacttta atttatcccc tttatattat ttatactact ctattatagt ctatttttat
    39841 ggacatttgg acatttttaa taaaagaaac agcagttata agttttcaat tttaactgct
    39901 gttataagtt aatataccaa acatttttaa ttaaattttt tttaatttta atacaaagac
    39961 ttaaatattc aatacaaatt ataaaaacac ttttatctag cttacttctt cttttctttg
    40021 tctaatttat ctaatttctt attgtataaa aacatataaa atgctgccga aaatactatt
    40081 aaatatccaa caacacttaa catatctgga taaacattga ataagaatat acttaaaatt
    40141 gctgaaaaga ttatattact atagtcaaat atagagattt ccttagcagg tgcatattta
    40201 tatgctagag ttattccaaa ttgacctaga cttgcaaata ctccacctag taatagatat
    40261 ataagttgca taagagtcat tggttcatat actgcaaaag caattggccc tacagtaact
    40321 aatgaaaaaa ctgaaaagaa aaatacaatt gtatagtaat cttctctatc tccaagaact
    40381 cttaaacaag tatatgccat tgctgcaaat acagctcctg caattccccc aagatatgga
    40441 attacttcta cactaaatgt tggttttatt atgaataaag ctcctataaa tgcaattata
    40501 atagctccta tctgctttat atttattttt tcttttagag caattgcaca aaatattact
    40561 acaaggaagg gactcatttt atttagcata ttagcatctg aaagcatcaa cttgtcaatt
    40621 gcatagtagt taaatataac tcctagagtt ccaaatattg acctatataa aagtactttt
    40681 aaattttctt ttttgccggt tagacttcct ttatgtttta tgataagcca aaaagctatt
    40741 atagctgata ccagatttct aaagaacact ttttgaaaac ttggtaaatc tccagctagc
    40801 tttacgaatg cagacatcat tgcaaagcca agcgctgatg ctattataaa cattatacct
    40861 tttattcgat ttgatttgat tgtgctactc atacgtacct cttttctata taaatgtata
    40921 aagccatatt aattaaaaac ttagcttata cattaaataa taattatcta aatattccaa
    40981 tttatactat aattaaaagt gtaaactatg tcaagtaact aataaatctt ttcaattaat
    41041 aacaataata attatagcta aaaagttata tgtttttatg gattattatc agaatatata
    41101 atataatttt atatagtata gacttttttt aatttattat ttagattttt aatagatttt
    41161 ttaactatgg aggtatttaa aatatggaaa taaagagata tgaaggaact ggaagaatga
    41221 gtagagctgt agttcataac aatacagttt atttatgtgg acaaactcat gctgaaggag
    41281 gagtaattga acaaacaact gaagttttgg ctaaaataga agatttatta aacaaatatg
    41341 gttcagataa gcaacattta ctatctgtta ctatttattt aagagatatg aaagactttg
    41401 aagctatgaa ctctgtttgg gatgcttggg ttgaaaaagg atttgaacct gctagagctt
    41461 gtgttgaagc tagacttgct agagagcatt tgttagttga aatgagcgtt gttgcagcta
    41521 caaaataatc aatttagctt ataggaggct atctcaaaat agagagataa gcctcttttt
    41581 cattgttgaa atgatgaaaa tatatttgat ttcatacaaa agaaagtgcc tcacgaacta
    41641 aaaaattcat tttgagacac ctcctcacta tttaatctat ataaatttac ttattctcta
    41701 ttggcaatat caatttagat ggatatttac ctccatggta aatcgtattc tttgcttcta
    41761 tatattcaat actattatat ccctctgtcg tgttactatt ttggaaaata aagtttttag
    41821 cactagatgt tatatctagt ctaattttat gaccaacttt aaacgtgttt gatatttttg
    41881 aagttataat cgtaaactta taaatctctc cttcttccat aaactctgac ttataaaaac
    41941 catttctaaa tctagcacta agtataccat cagctaattt aattgaattt ccatctaaat
    42001 ctacgtccat aatttttata acccagtcag tatctttggc agaacttgat gcaaaaaact
    42061 ctaactttat atcacctgtt acagtaaatt cttcactaaa agcatttgat gtataacaca
    42121 acatgtcact tcttttttct aaatctttgt agttatttgg aactccaact tcattctctg
    42181 acatatcaat tagttgtatt gatgggtctt ttggattata tatataacta tcatactttt
    42241 cttctaaatc actattaaat actaatctac catttcctaa agatgtgtta gcatttccat
    42301 cacttattag atacatactt ttatctatct tatttattat tggccaattt tcttctgtct
    42361 tccacttatt agaacctaaa gagtaatact ctactggagc agtcgtatct atgttatttt
    42421 ctataccttt taagtattta tcaaaccata atagataatt ataatccaaa tcatatctta
    42481 atgaactatt tcctaaagaa ataccattta tatctcttaa agtatttgaa ttatgcatcc
    42541 atggacctag aatagccttt ctctttcctt tttcatagtc ctttataaca tctaaggcct
    42601 ctgtagttcc catactatta tcatcatacc acccagatac aaccaatgca ggtacattta
    42661 ttttatcttt ttgtaaatgc caatccatca aatcccaata ctcatctttt tctactctct
    42721 ttaaccattc ttccagaaat tcaattctat atccaagagc ttcaacaggt atattctcta
    42781 ttggtcgtat atttaaaaca tcatcccaat catctcttac cattttactt ctatcaactt
    42841 tatttcttga taccataaat gcccatgcaa gcataccaga tacaaaagct cctccttttc
    42901 ttggtatatc aataaaaggg cttcctgatg ttactatact aactaaagct ttaagatgct
    42961 tattgcttga agatgcagct gcccattgga cataaccaag atatgatgct ccaagcattc
    43021 caactattcc acttgaccat tcctgtgata ctatccaatt tatggtacta tctccatctt
    43081 ccctctcatg aatcataggt tcccatttac cttctgattc atttcttccc ctaacatctt
    43141 gtattacaac agcatatcct ctttgtacat atttataata tatttcttta tcattttctt
    43201 ttccatatgg agttctcata agaattgttg gtgttttttt ggtagaatct acaaaattag
    43261 ggagatatac atctgtagaa agttttatac catctttcat atcaatcata taatttccac
    43321 caaatcttat agaatatatc tcttcatttt tatgagtttt ttcccattct tttaatacag
    43381 tatacttttc atatccatcc ataattaata tagtacaagt ttctctggat aaacagataa
    43441 aacctactat tttattatct acaataatta tatctagtgg gaactttttg tttctttgaa
    43501 cccatatata ttcattaagt ttagaatgcg tttctcctaa gttatttata actgtgtctt
    43561 tatctgtgtt tactaagctt ttagtatata catcaaagtt attaaataaa gactttaaat
    43621 ctatttttgt aagatttaaa tagtatgtat tttcttctct gcttattggt tttaaacttt
    43681 ctattttatt tgtaaaagga ttcaactttt caattaataa atcgccatca aagattacat
    43741 ttccactgta tagtccagat atgtataatt taaattttat caattaaact cccccctata
    43801 atcctagaga catctttatt gcatatgcca ctgatatacc tgcataattt cctaatactc
    43861 caccaattac tcccattacg actgctacac ttacaagcga attccacttt gcagaagcag
    43921 ctactaaagc tgaagtagga ccatcagcaa ttgctcctac tatagaaagt attacatatt
    43981 gatactttat ctttaaaagt ctagttatgc ctaaatggaa aacaaatgaa gcaaaaatta
    44041 tgctaaaaca gtaaagtgtt atagtaaaag ttgaacctaa aaactctttt atatctactg
    44101 aaaaacctat tgtacataaa aagaataatg caacaaataa tcctaaatct aaatttccct
    44161 ttagtttctt tactggcttt aattgagcaa ttataattga aattgttgta actaaaagta
    44221 ttcttgctgc actactaaaa cttgaattga aatatccagc aagtattgtt gaaacctctg
    44281 taacaacaaa acctatagcc aacatccaag ctatatcttt aatactccat tcttttgact
    44341 ccataaattc ttcattttga caatcctcta attctgattc ttctacatga tatggccaaa
    44401 gttttttaaa cttctttgaa ttttttaata ttgctggtag agcaaacata aatatcaatg
    44461 ttggtactcc aattacatag tctgctgcat ttgctgcagc aagagtttgt ctacttacat
    44521 taagacctgt tccaatagct gtaagattag cacttccacc agtgtatgta cctacaaaca
    44581 ttccagcaac cttccaacct tctgatattt tttctgcaaa tactaatcca aataaaaatg
    44641 ccatgatact tacagttaat acggctacaa gaattgcaat taaaggttct cttgataatt
    44701 ttgtcatttc ttttaagtca acactcatca acattatagt catagaaact ggaatagcat
    44761 atgttgaaat agttccatat aattcagtac ttactggaac tacttttaag tttgaaagta
    44821 ttattcccat tatgattatt gtaagtgctg gtcctaagct tttaatggct ttgtatcttt
    44881 gtaagtaaaa acccaatgca atcattgatg tcattacagc aagtatacta cctggatttg
    44941 aaaaaagtgt attcatattt aacctccaaa tttatcataa gtttacttct attcctaaac
    45001 ctggtttatt gacaagattc ataatatctc catccattac aaatcctcca gatatatctt
    45061 ttgattcttc acaaaacata aaactatcaa ggtcagcttc tgttatgttc tttttagatg
    45121 ctattaaatt tgctgctgct gttataccaa ttctcgtttc cagcatacat cctagcatac
    45181 aatttactcc acttgcctca gctatgttgt tgatttttat agcaggatat attccacttg
    45241 atttcatcag cttaatatta aatgtatcaa ctgcattctt ttttatagcc ttaattgcat
    45301 ctattggtga atgtaatgat tcatctatca taatttttgt attactttta tttcttatgt
    45361 aagcagtacc atctaaatcc caatgtggaa gtgcttgttc aattgcatca acattaaatt
    45421 cttctaactt tttgatagta tttatactgc tatttacgtt ccatccttga tttgcatcaa
    45481 ttctaattct tatactctct ccaacagttt ttctgattaa ctttacagct tcaatatcat
    45541 cttcaggatt tatacctgct ttaagcttca atatcctaaa accttctttt actctttcta
    45601 aagcttctac tgccattttt tctggcttat ctatacttat agtaatatcc gtttggactt
    45661 tactatcaaa tcctccaaga actttataaa gaggtgcatt cataattttt cctttaatat
    45721 catataaagc tatgtcaata gctgcttttg cagaagtatt acctataata attccatcca
    45781 tgattgtatg tatggtttca atatctagtg ggtctttgcc tattaactct tttttaaaca
    45841 taagcaatac tgaaagaaca ttatccaaaa cttcacctgt aactgctgca agaggtgctg
    45901 cttcgccaaa tccacaatac ccttcatcag tttcaatttt taaaattata ctttctccat
    45961 attcaattac tccaaatgaa actactacag gtttttttaa tttaattcta agcttttcaa
    46021 atttgatatc tgttatcttc atattaccct ccttattttt tgaagttata attcaatttt
    46081 taaaatttta tactttaaat tatattatta cttcaatata tatgtcaaga taatttactg
    46141 aaaatttact cttttccaaa atataatgtg ataatcttag ttcaattaat actcttctat
    46201 taaatttttt tattattatt ttctttatat taatttaaca ataattcatt ttcatagact
    46261 tttatttgca tttaattaaa ttttaattgt caaaatctac tatgtattct tattgccact
    46321 acttctatgt tatgctataa ttactttgtt ttaagcgaat attttatatt aattttatta
    46381 tttggaggtt cttatgctag gtgaaaagat gagaaatata agaaaaagca agaaaaaaac
    46441 attaagtgat gtttccaaat tgacagattt atctataagt tatatctctc aaatagaaag
    46501 agatgctatt gaaccatcct tgtcttcatt gagaaaaatc gctgaagttt tagacactcc
    46561 tttatatatg tttatggatg acaacaatac tgatgattta gtcattagaa aagaagatag
    46621 agttatgatg aaatttccaa agagtgaaat gttttacgag atagtatctc caatgcctac
    46681 aactgagttt acaccttcaa ttttatttgt agagtttgaa cttaaaccag aaagtgagga
    46741 tgccaaagat tatatctatc atgcatcaga agaaattatg gtggtaacga gtggtgtggt
    46801 tgatatttgt atgggcgaaa aggtagttag attaaatcca ggtgactcaa catttataaa
    46861 agctaatgta ccacataaaa tcatcaatcc aagtaaagat acaatagctc gtggatatgg
    46921 agttatatca cctccaattt ggccaataaa atctaaataa actcaatata atatacctac
    46981 tttttgtaga taatacaata aatttaaata tcacttttat tttaaaattg aagtatttat
    47041 ttaaatttaa aatatttact caaactaaaa aaatagctat ttgactaatc taaaccatct
    47101 taattatggt aaatagtaaa tagctatttg taagttatat tataaattat aataaaaatt
    47161 gtatttgtta aaattaaatt aaactgctat atcatttaat acttttgcct ttacaactct
    47221 tatatttttc atactcttgt agatatcttg aatcttatct tcttgctctc tcaatagtct
    47281 atgtgcttca tatatatcta caagttcaaa ttttactaca tcatttggct ttgcttgtgc
    47341 taacttatac aaatctacac ttataatgtt ccctatctta gtatagccac cactagtctg
    47401 tctatctgat aacattataa taggttttcc atgaccaggt acttgtatag ctccataaga
    47461 aataccatca gatataatat ctgctccatt aaggtgcttt atactctctc catctagtct
    47521 acaacccatt ctatctattt cattcgtaac tttgtattta tttgataaaa atttctctac
    47581 ttcaccttta gaaaaagcat caaattgagg accttttaca attcttagta cgatttctga
    47641 actataagtt ggaatatatt ttgaatttaa ttttttattt attgtaaaat ctttttcctg
    47701 aataaaagta tttatataat ctcctttttt aagtgctcta ccttcaaatc caccaatttt
    47761 agctcttgta taagttgact tacttcccat tgcaagtgga acatctattc caccagctat
    47821 tgacacatag gctctagcac ctgatttcac acctctaaat gataatacat cacctggatt
    47881 tatttgatat gacctccagt tttgaatttc ttttccattt attttagccc ctaagtctcc
    47941 cccagttact gctatttgcg tatattcatc aaaggtaatt gtagggccta acattaaaac
    48001 ttctaaagaa gcctcatctt cagaatttcc tactaatata tttcctactc tatgtgcata
    48061 ctcatccatt gctccacatc cagatacacc atattgacca tatccaactc tacctctgtc
    48121 ttgtattaat gtttggaaac ctcctaattc aactttgaat cccatatata ccactccctg
    48181 tactataacg atatttaaat acttaagtta tttttttcga tttctataaa ttcatctaat
    48241 gttattggaa caaattttat aaagtctcca gctctaagca aaatctgttc ttctctattt
    48301 tcatcatata attttaaagg tgttctacca attatttgcc atccaccagg actatcaata
    48361 ggatatacac cagtctggga acctgctatt ccaacactcc caccataaat tttagtcctt
    48421 ggcacttcta atctaggtgt agctattctt tcatccatac cacctagata tggaaatcca
    48481 ggagtaaacc ctagcatata tatcaagtac tctctacttg tgtgtatttt tataacttca
    48541 tctacagtga gattattgta acttgcaaca tttttaatat ctataccaaa aacttcatca
    48601 taacatactg gaatctcatg tattttaggt tttggtaata ctatactttc caaattatct
    48661 tctatttttt ttaaattctc aatcaaacta tcaaaatcta tttttaatgg attataactt
    48721 atcataagtg acctatatgt tggcaccatt tctgttacaa tacctttaag attcgatatt
    48781 tctattgctc tcataaatga aattactttt ttgtttatat cttctgatat ctcatttcca
    48841 aattcagcaa ccactgcctt atcccctgat atcaagtatc tagtttccat aaatgtcacc
    48901 tcttctaaat taagcaaata aagcacctag gctgctaaga gaagttattc ctgtatatgc
    48961 agatattaaa actactatta atccaaatat caaaagccat gtaggatgct tgtaatctcc
    49021 aacaatatct tttcttttag atgctataag cataattcct aatgtgattg gaagtatcaa
    49081 tccatttaaa gcccctgcta aaattaataa agtagctggt tttcctataa atgccattat
    49141 aagtgttgat attgctataa atgctattat aaaatatttt tcatatttat ctataaaagg
    49201 atttagtgtc tttaagaaag atactgatgt ataagcagct cctataactg atgtaattgc
    49261 agcagaccat aatacaagcc caaagaattt atatcctatt gctcctgcac taaatttaaa
    49321 agctgaagca gctggatttt ctgggtcaag ttgaagacct tttgaaacta ctgctagtat
    49381 tgctaaaaat aaaagaactc tcatcattgt ggcaactaat atacccaaaa gagaagattt
    49441 agttatttct tttatatttt cttctcctgt tattccacca tctattaatc tatgtcctcc
    49501 agcaaaagtt atataacctc caacacttcc tccaagtaga gttattattg ggaatatcaa
    49561 tccttttgga ttttctggtt ttaccattct ggatactgcc tctccaacag gaggatgatt
    49621 tgatattgct acatatccaa ctataattat cattcctaat gctaaaaatt tagttatctt
    49681 atccactaga gaatttgaat tttttgacat aaatacaaat atggctatta atccacttaa
    49741 tacagttcct aatgtcatat tcatattaaa cattacattc ataccaagtg cagctccacc
    49801 aacatttcct atattaaaag ctaatcctcc aagagctact aaaaaagcta ctaaatatcc
    49861 taatccaggt attattttat ttgctatatc ctgacctcta agtcctgata caccaattac
    49921 tctccataca tttacttgag cccctataaa aaggattgtt gtaattaaaa ttacaaatga
    49981 aaaattcggt ccaaaatctt gggtaaattg tgcagtctga gttaaaaacc ctggtccaat
    50041 tgctgatgtt gccattataa atgcagcccc tataagtgct ccaacatctt ttttattttt
    50101 agttttatct gtaatatttt ttgtactcat attttatctc cccctcatgt tatcagtctt
    50161 atactatgtt ctctgacgaa caaacttcta tgttttctaa tggacaaact tctatacttt
    50221 ctaattcaaa acgctttctt atttctttga caaactctat tgcttttgga ttgtccccat
    50281 gtacacatat agaatctgct ttgatatgta taacttcacc tgttaaagtt tctacagttc
    50341 cttcttttac catcctaaca actctatcta ttgcatgttt tgtatcatgt ataactgctc
    50401 cttctacgct tcttggaacc aaaaaaccat tattatcata agctctatct gcaaatactt
    50461 catttgcaaa cctaagtcca atttctttag cagaatttat catttcacta ttatatagcc
    50521 ccaacagtat aatatcttta tctacttcat atatagcttc acaaatcccc atagctaact
    50581 ctttatcttt agctgccata ttgtataatg ctccatgtgg ttttacatgt tgtatattac
    50641 atccatttga actcgcaaat gccattaaag cacctaattg atattttgta taatctttag
    50701 cttcctgctt cgttattttc atctcacgtc ttccaaatcc tattaaatct aggaaacctg
    50761 gatgtgctcc tattttcact ccattttttt tagctagctg tactgttttt tccatatgac
    50821 tagggtcacc tgcatgaaac ccacaagcta tattggccga tgaaatatat tttaaaactt
    50881 cttcatctaa accaatctta tacgttccaa aactttctcc taaatcacta tttaaatcta
    50941 ctttatacaa tttatgaccc ctccttgcta acattttgat agaataagta gttttaattt
    51001 ttaaattttg tttattttat atattgcatg aaatatttta tcacttgtat tcaattttat
    51061 ttttgcaact attctattgc atttaattaa tataatttta ccatttaagg aatattttta
    51121 caattatttt aatttaacat tcatttgtat ttctttttca aaaaatgttt ttaccatttt
    51181 ttagttaata attaattatt ttcacttaaa acaagggatt taaccttcat ttttaaagta
    51241 tttttcattt ttaatcactt tatatgcaag acagaatcat ttttcttcat tcatttgttt
    51301 ctttcatcta tataattatc attctttgta agtaaaatat ctttatattt ttataattaa
    51361 ttctttatat agttttaagt ataataaaat catgtatact aaatgcatgt taaaatatta
    51421 ttttaaaaca tgcacaatat ttatacatat tgtagacata taaacctata aattatacaa
    51481 tagtattgtt aagattatat atttttttaa tataaatttt gtattggggg aaaaacaatg
    51541 gataaaaact atacgatgcc aatataccaa aaaatagcgt tggatattgc aaataaaata
    51601 tacacgggtg aaatacaaga ggattcagta ttatttggac gctctgtttt ggctggtaaa
    51661 tacaatgtat ctccagaaac gataagaaga gctgtcaaaa ttttagagga cattggcgtt
    51721 gttaaaagca taaagggtaa aggtgttatt gtactatctc cagacaaagc ttcttctttt
    51781 ataaaaaaat atagagatat tacaaatata tcatcatata aatcaacact ttataattta
    51841 atagatacta aatctaattt agaaaatgaa atattagata ctataaataa aattttagac
    51901 tattctaaca gacttgaaat aatcaatcct ttagtgcccg ttcagttcac cataaattct
    51961 aattgcaaat atattggtca aacagctgca aaaactaaat tttggcaaaa tacaggcgct
    52021 acaatagttg caattaaaag aggtgaagaa cttataatat ctcctggacc atatattgaa
    52081 tttttagaag gagacattct cttagttgtt ggtgaccaac acatttacaa ttctatacca
    52141 atgtttttat atgaaaacga aaaataaatt atataattta gtatgattat ataaaaatgc
    52201 aaaattaaca acaaaaaaga gcttcatatt ttacataaag ctctttttaa attcaaataa
    52261 atttaacttt gattaatttt taaatatcca attcatcttc tttttcccag cttaaagctc
    52321 tcgatacagc ttttttccag cctttatata atttacatct cttctcttca ctcatatttg
    52381 gattaaactc tttttctact gaccactttg aagtaatttc atttcttcca atatataatc
    52441 caacagatag ccctgctaaa taagcagctc ctaaagctgt agtttctact attttgggtc
    52501 tatctatatc tacatttaat atatctgact gaaattgcat taaaaaatta ttattacttg
    52561 ctccaccatc aacttttaat gattttagtt ttaattttga atcgttttgc attgcttcta
    52621 aaacatcctt tgtctgataa gcaattgatt ccaatgtggc tcttactata tgttcttttt
    52681 ttgctcctct tgtaagtcct aaaattgaac ccctagcata catatcccaa tacggagctc
    52741 caagacctgt aaatgctggc actacatata caccattagt atcctctacc ctatttgcat
    52801 acatttcact atcttttgca gattcaatta tctttaattc atctctaagc cattgaacag
    52861 atgctcctcc aataaatata cttccttcta atgcatatgt tacttttcca tcaactcccc
    52921 aagcaattgt tgtaagtaac ccatgcttag atttaactat gttactgcct gtattcataa
    52981 gtaagaaaca acctgttcca taagtatttt ttgcagtacc ttcttcaaca caattttgac
    53041 caaataatgc tgcttgttgg tctccagcac atccagcaat aggtatttta gctcctgata
    53101 acatgcgctc atctgtatga ccataaacat agctagaagg ttttactaat ggcaacatgc
    53161 ttattggtat gtccaattct cgtaatatat cctcatccca ttctaaatca tttatattgt
    53221 acatcattgt tctagatgca tttgagtaat ctgttacatg tacttttcca cgagttaaat
    53281 tccatattaa ccatgtatct atagttccaa ataataactc tccttgttct gctttttccc
    53341 tagctccttc tacattatct aatatccatt ttacttttgt tgctgaaaag tatgcatcta
    53401 ttaaaagacc tgttttttct tttattgatt cttccaatcc tttattttta agttcatcac
    53461 atatttctga tgttctccta cactgccata ctattgcatt ataaataggt ttaccagtat
    53521 acctactcca aacaaccgta gtctctcttt gattagttat tcctattgaa gcaatttctt
    53581 ctggtcttat acctgctgtt tctataactt ctctcattac cccactttgt gacccccata
    53641 tttccatagg gtcatgctct acccatccag cttttggata aatttgattg aactcttttt
    53701 gtgcaatttt cactatttcg ccttttttat taaatagtat agctcttgaa ctggttgttc
    53761 cttggtctaa tgccattaca tacttctttt ccatcaccat attctcctta tcatataata
    53821 tttaatttat taaaaagaaa aatttaatat tacatatttc aataaataat catacttaag
    53881 tacaaattta atataataga tatttataaa aagacactta ttttctatca tatctatata
    53941 ataatattat acattatagc ttacatattg attaataaat tttaaaggag tataataaac
    54001 agtgttcata ataattttaa taaaagaggt ggtaatatgc caaaaatttt agaaaatgta
    54061 aaagaagata tattaaaagt atctcgggat atgattttag aagaagatta ctcgaatatt
    54121 agcataagga aaatagctca aaggtgtggt ataagtgcag gtacagtgta taattacttt
    54181 aattcaaaac aagaaataat agaatatatc acaaaatctg aatgggattt attgataagg
    54241 cgaattgaat actccaataa aaacactgaa gattacataa aaaaactaaa cattattttt
    54301 actgaaataa gaaattttat aaacaaagtt cataatatcc aatacaatga ctttttaaat
    54361 acttttgaaa cagagagatt ttttgaaatg aaaaaacaca aagacgactt tcatgaacag
    54421 ctttcaaata aagtatatga agctttagaa aaagaaagtt tttttaataa tgacaaatta
    54481 gtatgcaata tcataataaa aatgtttttt tcatattcaa catatcttca tatagaattt
    54541 gaagatttaa aaccctatat tgaaaaatta atacattaag gtggtgttta ccttgaatca
    54601 taatactagt attaagaaca aggacagtaa tccaaaaata tttttagtac ttacacttta
    54661 tctattaggt atatttatgg gagctattga tactggaata gtatcaccag caagaacgat
    54721 tatacaaaat agccttggag taaatgaaaa aacgggaatt tggatgatta ccatatacac
    54781 attaacatac gcttctgtaa ttcctatctc tggaaaatta gcagataaaa taggaagaaa
    54841 atatgtgtat ctagttagta tatttctatt tggtagtggt tcattaatat gtggattatc
    54901 atcactattt tccaatttct atattttatt aattggtcgt gttattcaag caattggtgg
    54961 tggtggaatc atgccaattg ctacagcaga atttggaact accttcccag aaaataaaag
    55021 aggcatggct ttaggtttag ttggggcaac atatggtatt gccaatattt taggttcaag
    55081 cattggtagc acaattctaa gtatatttgg aactcaaaat tggaagtggc tattttttgt
    55141 aaaccttcca atttgtttaa tcatacttat tggtggagtt ttctgtatta aaaacaataa
    55201 gtctgaatct aaagaaaaaa tagataagct tggtacatta atgttggtat gtataatcgt
    55261 atcactatta tatggtctta tgaatataga cttttttaat tttaaaaatt ctatacaaga
    55321 tatatcagtt tatccatact tattgacatt tattgtactt atacctattt tcatatttat
    55381 tgaaaataga gccaaagacc ctattttaag ctttgaatat tttttaaatc cgagaatatt
    55441 gatagtactt attttatctt taattgttgg tattggaatg atgggtatgg tattcgttcc
    55501 acagtatgct gaaaatgcat taaagataaa tgctggttct ggtggatatt ttgtagctat
    55561 attgggatta tttgcaggta ttgctgctcc tttaagtgga agacttattg acaagtttgg
    55621 ggcaaaaaaa atactattac taggattttc tgtatctatg ataggctctc tttacctagt
    55681 tttaattgct ctaaaaacca atactgtatt tagtgtatgt gtaagtttaa tatttatggg
    55741 attaggaatg ggatttacta tgggaactcc tctaaactat atgatgttat caaatacaag
    55801 attagaagaa tctaattcag cacttgcaac attatccttg atacgctcaa ttggtacttc
    55861 aatttctcca gctataatga ttggatttat agcacatgca ggattatctg tgcaagataa
    55921 tattatggac ttagttggaa agccctcaac tcctaaaata gttcaacttg aagaacttga
    55981 aaacatgata gatgacttaa aatcagaccc tgaaatggca aaaaatttaa aaaatgtctc
    56041 tatcccaaat atgaatgata cttcaaatat aaatatggac atgacaggtg gcaaacttcc
    56101 aaaatcctta cttaataaag ttcagtcagc agatacaacc aacattacca atataacaaa
    56161 agaaatatca acaacaatgt ttgatgaaaa agttccatct ataattacta aaatacagaa
    56221 aaatgtacaa aaaggaatag atggaacaca aagtggaata aacggtattg aagatggtga
    56281 aaataaacta aatagtggta ttaaaggagt tcaaactggt attgacaata tggtaaaagc
    56341 tagagctggt attaatcaag gaatagatgg tgtaaaaaaa ggtattgctg gtgttgacaa
    56401 aggtataaaa ggtatggaac aaggtcttga aaaacaagat gaggccatca aggaacttac
    56461 aactgcttat aataaaatac ctactacaga aaaaactcct actgataacg aaaataactc
    56521 aaatgaacaa aaccagagta ataccagtaa ttctgaatca gacgacacta agaatgattc
    56581 tacagaaaat aagaataaca attccagcga gaataaacca aatgtaaatg aacaaaaaga
    56641 aagtttaaat gctcaaatac agcaactaaa aaagacaaga gatgacttaa atacaaagtt
    56701 acaaaaaaat aaaactcaaa agaacgaatt aagtaaaaaa ctaagatcaa tggaatctca
    56761 aaagaaagag ctacaaagca agttaaataa ttctataagc caaaagaaag acatggaaaa
    56821 aagccttgat acaatgcaac agcaaaaaaa atcactccaa gcagttttag caaagacaca
    56881 agaggtaaaa actgaaatac caaaggcttt tgataaatca aaattggatt atataaattc
    56941 catagaaaat aatagaacaa aaatagaaaa tacactacaa tctactctaa actcaggatt
    57001 taaacagatg tatataacag tattctgtgt aaatctacta gcatttataa tattattgtt
    57061 ctataaagaa aataaaacta gataaaagag tgttatagta ttatattgta aatttatctt
    57121 attcttaaat attttattct aaagaata
//
LOCUS       DAEQAF010000013        56314 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.013, whole genome shotgun sequence.
ACCESSION   DAEQAF010000013 DAEQAF010000000
VERSION     DAEQAF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56314
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.013"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            55..171
                     /gene="rrf"
                     /locus_tag="KRN00_000927"
     rRNA            55..171
                     /gene="rrf"
                     /locus_tag="KRN00_000927"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            179..253
                     /locus_tag="KRN00_000928"
     tRNA            179..253
                     /locus_tag="KRN00_000928"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:211..213,aa:Asn,seq:gtt)
     gene            259..344
                     /locus_tag="KRN00_000929"
     tRNA            259..344
                     /locus_tag="KRN00_000929"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:293..295,aa:Leu,seq:taa)
     gene            360..435
                     /locus_tag="KRN00_000930"
     tRNA            360..435
                     /locus_tag="KRN00_000930"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:393..395,aa:Met,seq:cat)
     gene            443..517
                     /locus_tag="KRN00_000931"
     tRNA            443..517
                     /locus_tag="KRN00_000931"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Glu,seq:ttc)
     gene            532..605
                     /locus_tag="KRN00_000932"
     tRNA            532..605
                     /locus_tag="KRN00_000932"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:564..566,aa:Gly,seq:tcc)
     gene            611..686
                     /locus_tag="KRN00_000933"
     tRNA            611..686
                     /locus_tag="KRN00_000933"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:644..646,aa:Val,seq:tac)
     gene            692..768
                     /locus_tag="KRN00_000934"
     tRNA            692..768
                     /locus_tag="KRN00_000934"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:726..728,aa:Asp,seq:gtc)
     gene            779..853
                     /locus_tag="KRN00_000935"
     tRNA            779..853
                     /locus_tag="KRN00_000935"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:811..813,aa:Gly,seq:gcc)
     gene            863..936
                     /locus_tag="KRN00_000936"
     tRNA            863..936
                     /locus_tag="KRN00_000936"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:897..899,aa:Arg,seq:tct)
     gene            1920..2759
                     /locus_tag="KRN00_000937"
     CDS             1920..2759
                     /locus_tag="KRN00_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBH1826805.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2756..3937
                     /locus_tag="KRN00_000938"
     CDS             2756..3937
                     /locus_tag="KRN00_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826806.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDNKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4241..5143
                     /gene="ptb"
                     /locus_tag="KRN00_000939"
     CDS             4241..5143
                     /gene="ptb"
                     /locus_tag="KRN00_000939"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBH1826807.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5165..6244
                     /gene="buk"
                     /locus_tag="KRN00_000940"
     CDS             5165..6244
                     /gene="buk"
                     /locus_tag="KRN00_000940"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1826808.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6234..6911
                     /locus_tag="KRN00_000941"
     CDS             6234..6911
                     /locus_tag="KRN00_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1826809.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            6954..7169
                     /locus_tag="KRN00_000942"
     CDS             6954..7169
                     /locus_tag="KRN00_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1826810.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7198..8277
                     /locus_tag="KRN00_000943"
     CDS             7198..8277
                     /locus_tag="KRN00_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1826811.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8277..9029
                     /locus_tag="KRN00_000944"
     CDS             8277..9029
                     /locus_tag="KRN00_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1826812.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9030..9587
                     /locus_tag="KRN00_000945"
     CDS             9030..9587
                     /locus_tag="KRN00_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1826813.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9757..11103
                     /locus_tag="KRN00_000946"
     CDS             9757..11103
                     /locus_tag="KRN00_000946"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBH1826814.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSSPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATNLANLIQEKLS"
     gene            11370..13202
                     /gene="glmS"
                     /locus_tag="KRN00_000947"
     CDS             11370..13202
                     /gene="glmS"
                     /locus_tag="KRN00_000947"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBH1826815.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13654..14949
                     /locus_tag="KRN00_000948"
     CDS             13654..14949
                     /locus_tag="KRN00_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBH1826816.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYSDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVANYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGKESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLIVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15377..16114
                     /locus_tag="KRN00_000949"
     CDS             15377..16114
                     /locus_tag="KRN00_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBH1826817.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            16135..17388
                     /gene="murA"
                     /locus_tag="KRN00_000950"
     CDS             16135..17388
                     /gene="murA"
                     /locus_tag="KRN00_000950"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBH1826818.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17475..18539
                     /gene="spoIID"
                     /locus_tag="KRN00_000951"
     CDS             17475..18539
                     /gene="spoIID"
                     /locus_tag="KRN00_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBH1826819.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18605..19273
                     /locus_tag="KRN00_000952"
     CDS             18605..19273
                     /locus_tag="KRN00_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBH1826820.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19371..19631
                     /gene="spoIIID"
                     /locus_tag="KRN00_000953"
     CDS             19371..19631
                     /gene="spoIIID"
                     /locus_tag="KRN00_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBH1826821.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            19828..20847
                     /locus_tag="KRN00_000954"
     CDS             19828..20847
                     /locus_tag="KRN00_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBH1826822.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            20863..21291
                     /gene="fabZ"
                     /locus_tag="KRN00_000955"
     CDS             20863..21291
                     /gene="fabZ"
                     /locus_tag="KRN00_000955"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBH1826823.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21402..21911)
                     /gene="yyaC"
                     /locus_tag="KRN00_000956"
     CDS             complement(21402..21911)
                     /gene="yyaC"
                     /locus_tag="KRN00_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBH1826824.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      22100..22203
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22340..23533
                     /locus_tag="KRN00_000957"
     CDS             22340..23533
                     /locus_tag="KRN00_000957"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBH1826825.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            23849..24946
                     /locus_tag="KRN00_000958"
     CDS             23849..24946
                     /locus_tag="KRN00_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826826.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPIIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25210..27429
                     /locus_tag="KRN00_000959"
     CDS             25210..27429
                     /locus_tag="KRN00_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBH1826827.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEIIKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27432..28214
                     /locus_tag="KRN00_000960"
     CDS             27432..28214
                     /locus_tag="KRN00_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBH1826828.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFVLTLLTKANDNYIME"
     gene            28546..30459
                     /locus_tag="KRN00_000961"
     CDS             28546..30459
                     /locus_tag="KRN00_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1826829.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIEGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKPLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            30600..30908
                     /locus_tag="KRN00_000962"
     CDS             30600..30908
                     /locus_tag="KRN00_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1826830.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            30932..31258
                     /locus_tag="KRN00_000963"
     CDS             30932..31258
                     /locus_tag="KRN00_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1826831.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31297..32631
                     /gene="celB"
                     /locus_tag="KRN00_000964"
     CDS             31297..32631
                     /gene="celB"
                     /locus_tag="KRN00_000964"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBH1826832.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            32642..33160
                     /locus_tag="KRN00_000965"
     CDS             32642..33160
                     /locus_tag="KRN00_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBH1826833.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLNDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            33256..34215
                     /locus_tag="KRN00_000966"
     CDS             33256..34215
                     /locus_tag="KRN00_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBH1826834.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCAATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIERRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34264..35316
                     /locus_tag="KRN00_000967"
     CDS             34264..35316
                     /locus_tag="KRN00_000967"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBH1826835.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHHPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35319..35993
                     /locus_tag="KRN00_000968"
     CDS             35319..35993
                     /locus_tag="KRN00_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBH1826836.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDIGVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVDNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            36546..37097
                     /gene="raiA"
                     /locus_tag="KRN00_000969"
     CDS             36546..37097
                     /gene="raiA"
                     /locus_tag="KRN00_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH1826837.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37229..39904
                     /gene="secA"
                     /locus_tag="KRN00_000970"
     CDS             37229..39904
                     /gene="secA"
                     /locus_tag="KRN00_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH1826838.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            39919..41026
                     /gene="prfB"
                     /locus_tag="KRN00_000971"
     CDS             join(39919..39993,39995..41026)
                     /gene="prfB"
                     /locus_tag="KRN00_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBH1826839.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            41170..43311
                     /locus_tag="KRN00_000972"
     CDS             41170..43311
                     /locus_tag="KRN00_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBH1826840.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43459..44625
                     /locus_tag="KRN00_000973"
     CDS             43459..44625
                     /locus_tag="KRN00_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1826841.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEGFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKTLGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44685..44802
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            44927..45532
                     /locus_tag="KRN00_000974"
     CDS             44927..45532
                     /locus_tag="KRN00_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1826842.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            45861..46901
                     /locus_tag="KRN00_000975"
     CDS             45861..46901
                     /locus_tag="KRN00_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1826843.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            47040..47492
                     /gene="tsaE"
                     /locus_tag="KRN00_000976"
     CDS             47040..47492
                     /gene="tsaE"
                     /locus_tag="KRN00_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBH1826844.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            47492..48208
                     /gene="tsaB"
                     /locus_tag="KRN00_000977"
     CDS             47492..48208
                     /gene="tsaB"
                     /locus_tag="KRN00_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBH1826845.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            48198..48674
                     /gene="rimI"
                     /locus_tag="KRN00_000978"
     CDS             48198..48674
                     /gene="rimI"
                     /locus_tag="KRN00_000978"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBH1826846.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48680..49696
                     /gene="tsaD"
                     /locus_tag="KRN00_000979"
     CDS             48680..49696
                     /gene="tsaD"
                     /locus_tag="KRN00_000979"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBH1826847.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREILSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            49993..52701
                     /gene="hpdB"
                     /locus_tag="KRN00_000980"
     CDS             49993..52701
                     /gene="hpdB"
                     /locus_tag="KRN00_000980"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBH1826848.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEIKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52705..52962
                     /gene="hpdC"
                     /locus_tag="KRN00_000981"
     CDS             52705..52962
                     /gene="hpdC"
                     /locus_tag="KRN00_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBH1826849.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            52955..53905
                     /gene="hpdA"
                     /locus_tag="KRN00_000982"
     CDS             52955..53905
                     /gene="hpdA"
                     /locus_tag="KRN00_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBH1826850.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSDENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            54221..55183
                     /locus_tag="KRN00_000983"
     CDS             54221..55183
                     /locus_tag="KRN00_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1826851.1"
                     /translation="MNKSWSNLIIKNKDRKVRSGWIIIAVMATFYILQYYLSMTLVEI
                     IRKILIATGDINLKTNYFSEYANWVSDVGLQVVFQILTESLTIIIPIIVWRFIMKNPI
                     REMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVYWILF
                     FALVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLVHIWNPDVTLLSVINIITI
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPISGLQVPEIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSDKVNVTNIKN"
     gene            complement(55282..56262)
                     /locus_tag="KRN00_000984"
     CDS             complement(55282..56262)
                     /locus_tag="KRN00_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1826852.1"
                     /translation="MNLKLIWINILNPVFIKNEIKRKKIQIIIFFFINFGLTYSLGLL
                     LYYNKFIDPENFASFMMILPLSSVAIAKFYTEGLNNDMYEFYSLIILFFLIYSLLIVL
                     KLLNLINNNEFIIINLILTFISSLSIIIYSSNKKNLYPVKNIKLGSLLIIYFMISVIV
                     PTSFILILQGAQPNYSGIIKFIFTPITSLTTIYIFFSEEYAWRGFLQNIFFDKFGKKL
                     GVIILGMCWSLWHLPLIFTLYTPEAPILGIILRSIHIVGISIFLGYLYIKTKNIWFCA
                     IIHVLNNSAFLITNSKESTITYHDILIVSMVVLIFYVPFLFTKEYKNNLE"
BASE COUNT        22568 a         6094 c        10664 g        16988 t
ORIGIN      
        1 ctaggttcta taaacttatt aaaaacttaa tagaaatatt aagcataaag attatgtggt
       61 tacaatagca gagaggatac acctgttccc attccgaaca cagaagttaa gctctctagc
      121 gctgatggta cttggtggga aactgcctgg gagagtagga cgtagccacg ttaaatgttc
      181 caaggtagct caacggtgga gcaaccggct gttaaccggt aggctgtggg ttcgagcccc
      241 acccttggag ccaaaaaagc cgaagtggcg gaactggcag acgcacagga cttaaaatcc
      301 tgcgggactt acctctcgta ccggttcgat tccggtcttc ggcacttata aaacaatatc
      361 gcggggtgga gcagttggca gctcgtcggg ctcataaccc gaaggtcgta ggttcaagtc
      421 ctgcctccgc aaccattaaa acggctcgtt ggtcaagagg ttaagacacc gccctttcac
      481 ggcggtaaca ggggttcaat tcccctacga gtcaccaatt caattaaata tgcgggtgta
      541 gctcaatggt agagttctgg ccttccaagc cagctgtgag ggttcgatcc ccttcacccg
      601 ctccaaaaat gggaccatag ctcagctggg agagcacctg ccttacaagc agggggtcac
      661 aggttcgagc cctgttggtc ccaccattcg cggcctggta gttcagttgg ttagaatgcc
      721 agcctgtcac gctggaggtc gagggttcga gccccttcca ggtcgccaaa ttaaataagc
      781 gggaatagtt cagtggtaga gcgcaacctt gccaaggttg aagtcgcgag ttcgaatctc
      841 gtttcccgct ccataataac ttgggtgcat agctcagctg gatagagcaa cgcccttcta
      901 aggcgtgtgt ccggggttcg aatccctgtg cgctcattaa gaaaagttta ctataaatta
      961 tagtaaactt ttatattgtt taaaaagaca caggaaacat gtatattacc tgtgtctttt
     1021 tatttataaa ctttaaacta tgtaaaaatt acagtatatt ctaatagagt tacagtatat
     1081 tcattaatat tgtaaacata cggagggtaa tgtataatag tctacaagat gtttatgaag
     1141 gcatcagtta aatataataa atataactaa ttagtaagag ttatatacat tatattgtat
     1201 actttatggt atttatatat tgaaataact tatgaaatta tttataaaga gattcatgag
     1261 catatttttg tctaaacaat aagtataaga aattataaaa agttagagac tatagtgaat
     1321 ttacaattta atgtaatatt tataagttat actaaataaa ttattatact gtgaaatgga
     1381 tatataactt taggtattgt gtattatttt cactgtagga gattatatct agttatacat
     1441 aataagtttt aatgatagtt tatagtaaga tattaaaata aatttatcta atctagatat
     1501 gaaataagtt attactttaa tataaaaatg aatctaatgg aataatattg atgataagta
     1561 atatttagat tttgtatttg tttatagtta ataagtggat tatagaattt ataataatta
     1621 atatatatta aacaaagata tattaagata ttttagaaca taaaactgaa ttaaggcgcg
     1681 agtactattt tgtattcgcg ccttgatggt ttgagttatt tgagtaaaaa ctaactttaa
     1741 taagaaatat gtatttatta agttgatatt tttaatgtgt ttagagatta tttaacaatc
     1801 tccaaatata aaactataat tatttacata aaagttaaat agtttgtata gagttagatt
     1861 tatatagtat aatacttagt gtaaataatt aagaagttat caaacaggag gataaaactg
     1921 tgttagatat aaattctttt ttaaatggat tttttaatat aatattaaga atgagtatat
     1981 atgatttaat tgacatatct atagtagcgt atatttttta caaaatattt atgtttataa
     2041 aagatacaag agcagaacaa gtgtttaaag gtataatatt tcttttatta gcaactcaac
     2101 ttagtaacac ctttaaattg cataccgttt attggatatc tcttaaagct ttagattatg
     2161 gagttatagc tgctcttata atttttcaac cagaatttag agcaggactt gaacatatag
     2221 gaagagcaaa gttcaattta tttggaaaga atgtaaatac ttctgaagaa actctcaata
     2281 gaaatataga agaaattgta gaagctttat attcactttc tagacaaaaa ataggagctc
     2341 ttatcataat ggagagagaa actagaataa gtgatataat aaatacagga actattattg
     2401 atgctgaaat ttctaggcaa ctattaataa atatatttat accaaataca ccattacacg
     2461 atggagctgt tgtaattaga gattctaagg taaaagcagc tgcatgtttt ttgccattga
     2521 cagaaagtaa ggatttaagt aaagatttgg gtactagaca tagagcagga ataggggtaa
     2581 gtgaggtgtc tgactgtata actttgattg tatcagagga aacaggtggc gtatcaattg
     2641 ctaaagcagg taagttatat agagatattt ctagagaaag aatgatgaat atattacgta
     2701 gtaatttaaa aacaaataca gaaacaagaa gttttttcaa aggtggtata tttaaatgat
     2761 aaatagacta aaaaataata ccaaaataaa aataatatca tttttaagtg caattgcatt
     2821 atggatgtat gttatggctg tagttgaccc tgaagaaact aaagggtttg aagatatacc
     2881 tgtatctata agtaatatga gtgatttaaa ggataaaaat cttgttatat atccagacga
     2941 aaaattaaca gcagatgtat atataaaagg tagtttatca aaggtacaaa gtgttaaaaa
     3001 agaagatata catgtatatg gaaccattga agatccaata caaggacaga aggaagtata
     3061 tttaaaagca aatattcctc aaggtgttac tctagaattt aagcatgatg ttttagtagt
     3121 aaatcttgaa aaaaacataa aagaaaaaag agatataaag gtagaagtaa gtggaaattc
     3181 aaaaagaaat ataaataaaa ttgaacttag taaggaattt gtcgatgtat caggtccaag
     3241 aactctagtt aaagaagtca aaagtgtaag agctaatcta gatgttggta atgagacaga
     3301 tgatttttct aaaaaattgc aattaatacc attaaatagt gatggaacta aggttgaagg
     3361 agtaacatta agttcatcct ttgtgactgc aaagatagaa ctattgaagg aaaaaattgt
     3421 cccaataaga gtaagtctaa atgataataa agataatgat gtactgaaaa actataaatt
     3481 aagtaaggaa caagttacaa taaaaggaaa gaaagaagat atagacaaaa taagttatat
     3541 taagacaaaa cctattgact tagctgattt ggctaatggt gaagaaaaag aagttagctt
     3601 agaaattcca gagggtataa ctcttgagga tagctctata acaattaaat taaatgatac
     3661 aaaacaattg agtgcagaat ttttatataa tgcgggagat attgaattaa gaaatatccc
     3721 aacaaatatg gataatccaa atgtaatttc tgatgtagat ataaaagttg ttgtagagtc
     3781 aacggaggat ttgagtaagt taaataaaaa agatatttca ctatatattg atttatcaca
     3841 aggccctgag gaagataata aatataaaat aaaatatgaa acaacatatc aatttaaaaa
     3901 aataaatata gaacctaata ttgttgaagt ggaatgaaca aatatttcga atatttagtt
     3961 gttacaagat gcgacaaaaa aacctataaa attaagtttg ttaattttat gtttttgttg
     4021 catcttgttt attttagtta tattataaaa taaggacaat gagatatttg ttaaatctaa
     4081 aaagcgctag atatatgaaa aaagactgat aaatagattt aaataaatat tttgaattaa
     4141 atatttcaat tatctctagg aaaacgttgc tgaacgagtt ataatttaat tgagatataa
     4201 aaagttctat ttcaaaaaat tcaagatgag gtggaaatgc atgagaagtt ttgaagaagt
     4261 aattaagttt gcaaaagaaa gaggacctaa aactatatca gtagcatgtt gccaagataa
     4321 agaagtttta atggcagttg aaatggctag aaaagaaaaa atagcaaatg ccattttagt
     4381 aggagatata gaaaagacta aagaaattgc aaaaagcata gacatggata tcgaaaatta
     4441 tgaactgata gatataaaag atttagcaga agcatctcta aaatctgttg aattagtttc
     4501 acaaggaaaa gccgacatgg taatgaaagg cttagtagac acatcaataa tactaaaagc
     4561 agttttaaat aaagaagtag gtcttagaac tggaaatgta ttaagtcacg tagcagtatt
     4621 tgatgtagag ggatatgata gattattttt cgtaactgac gcagctatga acttagctcc
     4681 tgatacaaat actaaaaagc aaatcataga aaatgcttgc acagtagcac attcattaga
     4741 tataagtgaa ccaaaagttg ctgcaatatg cgcaaaagaa aaagtaaatc caaaaatgaa
     4801 agatacagtt gaagctaaag aactagaaga aatgtatgaa agaggagaaa tcaaaggttg
     4861 tatggttggt ggaccttttg caattgataa tgcagtatct ttagaagcag ctaaacataa
     4921 aggtataaat catcctgtag caggaagagc tgatatatta ttagccccag atattgaagg
     4981 tggtaacata ttatataaag ctttggtatt cttctcaaaa tcaaaaaatg caggagttat
     5041 agttggggct aaagcaccaa taatattaac ttctagagca gacagtgaag aaactaaact
     5101 aaactcaata gctttaggtg ttttaatggc agcaaaggca taattttaag ggggaaatag
     5161 gcaaatgagc aaaatattta aaatcttaac aataaatcct ggttcgacat caactaaaat
     5221 agctgtattt gataatgagg atttagtatt tgaaaaaact ttaagacatt cttcagaaga
     5281 aataggaaaa tatgagaagg tgtctgacca atttgaattt cgtaaacaag taatagaaga
     5341 agctctaaaa gaaggtggag taaaaacatc tgaattagat gctgtagtag gtagaggagg
     5401 acttcttaaa cctataaaag gtggtactta ttcagtaagt gctgctatga ttgaagattt
     5461 aaaagtggga gttttaggag aacacgcttc aaacctaggt ggaataatag caaaacaaat
     5521 aggtgaagaa gtaaatgttc cttcatacat agtagaccct gttgttgtag atgaattaga
     5581 agatgttgct agaatttctg gtatgcctga aataagtaga gcaagtgtag tacatgcttt
     5641 aaatcaaaag gcaatagcaa gaagatatgc tagagaaata aacaagaaat atgaagatat
     5701 aaatcttata gttgcacaca tgggtggagg agtttctgtt ggagctcata aaaatggtaa
     5761 aatagtagat gttgcaaacg cattagatgg agaaggacct ttctctccag aaagaagtgg
     5821 tggactacca gtaggtgcat tagtaaaaat gtgctttagt ggaaaatata ctcaagatga
     5881 aattaaaaag aaaataaaag gtaatggcgg attagttgca tacttaaaca ctaatgatgc
     5941 tagagaagtt gaagaaagaa ttgaagctgg cgatgaaaaa gctaaattag tatatgaagc
     6001 tatggcatat caaatctcta aagaaatagg agctagtgct gcagttctta agggagatgt
     6061 aaaagcaata ttattaactg gtggaatcgc atattcaaaa atgtttacag aaatgattgc
     6121 agatagagtt aaatttatag cagatgtaaa agtttatcca ggtgaagatg aaatgattgc
     6181 attagctcaa ggtggactta gagttttaac tggtgaagaa gaggctcaag tttatgataa
     6241 ctaatgataa aagaataaga atcataactg gtcactatgg aagtggtaaa agtgaatttg
     6301 cgatgaacta tgttgttaag ttaagagata tggtttctgg caaagttgct atagccgatt
     6361 tagatgtggt aaatgtatac tttagaacta gagaaaagaa agagttaatg aaatccttag
     6421 gtatacaacc aatagatagc tcaattaatg ctccaacatt agatttacca gcagtatcag
     6481 cagaggtaat gtctcctatg gtagaccatt catacaattc tgttatagat ttaggtggag
     6541 ataatgtagg tgctagggtt ataggaagat ttagtcattt gttaaaagaa ggcgattatg
     6601 atatgctttt tgtaataaat gcaaataggg agaaaactca aacttctgaa gaagttatcc
     6661 aatatataaa agaaatagaa aaatcttcta aattaaaggt aacaggtcta attaataata
     6721 ctcatcttat taggtttact actattgatg atgttttaag aggtcagaaa gttgcaaaag
     6781 aagtttctga aaaatgtaat ataccgataa gatatgttgc atgtttagaa aatcttgttg
     6841 aacagttacc aaaagattta gaaggagaaa tttttcctat aaaattatat atgagagaag
     6901 actggatgta gtttgagctc aaatatatag aaagtttaag gaggcttagg taaatggcta
     6961 aaggaaaagt atcttttaat caagaacgtt gtaaaggttg tggattgtgt gttgaagcat
     7021 gtccagtaaa aatcatacaa ttagactcaa atgtaataaa caaaaaaggg tataacccag
     7081 caactgtttt tgaaatggaa aaatgcatag gatgtgcaag ttgtgcaact atgtgtccag
     7141 atgtagttat aacagtagaa agagattaat ttaattaata tttaaggggg aattttaatg
     7201 gctaagatac ttatgaaagg taacgaagca tttggaaaag cagctataga agctggttgc
     7261 aaatatttct tcggttaccc aataactcca caaagtgaat taccagaata tttatcaaga
     7321 gagttaccta aaataggtgg agcgttcgtt caagctgaat cagaagtttc tgcgataaac
     7381 atggtttatg gtggagcagg tgcaggagca agagttatga cttcttcatc ttcaccagga
     7441 gttgctttaa agcaagaagg tataacatat gcagtaggag cagaagttcc ttgtgttgta
     7501 cttaatgtaa tgagaggtgg tccaggactt ggaagtatac aaccttcaca agctgactac
     7561 tttatgtcta caagaggtgg aggaaatgga gactacagaa ctccagtatt cgcaccagct
     7621 acagttcaag aagctgttga tatgataatg gaagcttttg acgttgcaga ttattacaga
     7681 tcaccagtta tggtagttgc agatggtatg ataggtcaaa tgatggagcc agttgaattt
     7741 agagctcctg agaagaaaag agaattgcct cctaaagatt gggcaactgt tggaactaaa
     7801 ggaaaaagaa aacctaatgt aataaactct ctatacttag agccagaagt actagaagac
     7861 cattgttggc atttacaaga aaaatttgat gcaatggaaa agaatgaagt acaatacgaa
     7921 atgtacaaaa cagaagatgc tgaatttgta tttgcagctt atggaactac ttcaagagta
     7981 gtaaaaagcg caattgatat attaagagaa gaaggaataa aagcaggtct tataagacct
     8041 aaagtattat ggccattccc attcgaagca ttcaaccaaa ttcctaatgc tagaaacata
     8101 ttgactgttg aaatgagtat gggacaaatg gtggaagatg ttaaaatggc agtagaaggt
     8161 aaattaccag tttacttcca tggaagacca ggaggaatga ctccaacacc agcagaaata
     8221 gttgaaaaag ctaaaaaaat tattgccgga gaattggttg caggaggtgc tagataatgg
     8281 ctgttgtatt taagaaaact gaaggattac aagatactca aactcactac tgtccaggat
     8341 gtacacatgg tataatccat agattagttg gtgaagtatt agaagaacta ggagtattag
     8401 gtgatgctgt aggtgttgtt ccagttggat gttcagtttt aggatataaa tattttaact
     8461 gtgacactca agaagctgct catggtagag cgccagctgc tgctacagga ataaaaagag
     8521 ttcatcctga aaatacagta ttcacttatc aaggtgatgg agacttagct tcaattggta
     8581 ctgctgaaat agttcatgca gctgctagag gagaaaaaat aactactata tttgtaaaca
     8641 atacaactta tggtatgact ggtggacaaa tggctccaac tacattagtt ggacaaagag
     8701 ctactactgc tcaatcagga agaaatgctg aaactcaagg ttatccaata agagtaagtg
     8761 aaatgttagc tacattaaca ggagctgtat ttgtagaaag agtagcagtt gatactccag
     8821 ctcatgttag acaagctaaa aaagctataa agaaagcatt ccaagttcaa caagcaggat
     8881 taggatttgg aatagtagaa gtattatcta cttgtcctac aaactgggga ctagctccaa
     8941 atgatgcttt acaatggtta agagacaaca tgataccata ctatccatta ggaaatttca
     9001 aaaatgttga agttgaggag gtgaagtaaa tgtctacagc tagagtaata tgtgcaggct
     9061 tcggaggcca aggtgttatg tctatgggac aattacttac ttatgcagga atgctagaag
     9121 gaaaagaagt ttcttggtta ccatcttatg gaccagaaat gcgtggaggt acagcaaact
     9181 gtgcagtaac tgtatctaat gagccagttg gttctccact tataacagat gatgcaactg
     9241 cagctatatt attaaatata ccagcatttg aaaaattcaa agatgatgtt attcctggtg
     9301 gaaaaataat agtaaatagt tctttaataa aagaaaaagt tgatagaaca gatgtagatg
     9361 tttattatat accagcaaat gaattagcag ctgaattagg aaatgataaa gttgctaaca
     9421 tgataatgtt aggcgcttac ttaaaagtat ctgatactgt agatatagaa tctgtactag
     9481 aagcattcaa aaaagttttc ggacctagaa aagaaaaatt cgttccatta aacagagaag
     9541 ctttacaaaa aggtatggat gctacatgtt ctaaagcaac taactaataa agaaaaagat
     9601 gtcaaaaaaa agacaataga attatttcta ttgtcttttt tgctgataag tattaaaata
     9661 tttttatgac tgaaattaag cctataatga tattttatga actataaaaa tataatacaa
     9721 attacaagct tttcaattat gaaaggagaa tctttagtga gaaagtattt tggaacagat
     9781 ggagttagag gagtagcaaa tacagaacta acatgtgatt tagcatataa acttggtaga
     9841 gctggtggat ttgtcttagc tcaaggagac cacagagtaa aagtagtagt aggtaaggat
     9901 actagaatat caggtgatat gttggaagca tctttaatag caggacttat gtctgttgga
     9961 tgtgatgtta ttactgttgg aataatacca acacctgcag tggcatattt aactagaaaa
    10021 tatggtgctg attgtggtgt ggttatatct gcatctcaca atcctgttga atataatgga
    10081 atcaaattct ttaataagaa tggatataaa ttagatgatg aaattgaatt gaaaatagaa
    10141 gaatatatag acgatataga caaaattgat tgtcttccaa ttggtgaaaa tgtaggaaga
    10201 aaattacatg aacattgtgc acaaagagac tatgtagact acctaaaatc aataataagc
    10261 actgacttta agggattaaa agtagttttg gactgtgcta atggtgcgtc atataaagtg
    10321 gcaccaatag tgtttgatga actaggagca agtgtaattt caataaatag ttcaccagat
    10381 ggaaataata taaactataa atgtggctct acacatccag aacaacttca aagggctgtt
    10441 ttggaacata atgctgactt aggtcttgca tatgatggag atgctgatag attaattgca
    10501 gtaaatgaaa agggtcaaat tgttgatgga gaccatataa tgatattgag tgccttaaat
    10561 ttaaagaaaa ataataaatt ggcacaagat actttggtag ttacagttat gagtaatata
    10621 gggttgacaa tagctgctaa ggaaaatgga ataaatttat ctactacagc agttggagac
    10681 agatatgttt tagaagatat ggttaaaaat ggatataatc ttggtggaga gcaatctgga
    10741 catatgatat ttttagatta caacactact ggagatggag tgcttagttc tctaatactt
    10801 gcaaatataa tcttgcaaga aaagaaacct ttatcagaaa ttgcatcaat aatgagccaa
    10861 tacccacaag tattagtaaa tgcaacaata aaaaatgaaa ataagaacaa atatatggaa
    10921 tatccagaaa taaaaactga gatagaaaga atagaatcta ttttagacgg aaatggtaga
    10981 gttttgataa gaccatcagg aactgagcca ttagttagag ttatgttaga gggtaaagag
    11041 gaaggtcaaa taaaagaatt agcaacaaac ttagctaatc ttatacaaga aaaattatcg
    11101 taatttaaag ggtattctca gatataaata ctgaggacac ctttctaagc gccagaactt
    11161 agttatagac ataattattg agtaatatag gaactaagtt gacgaggtca gagttaatcg
    11221 aattgtcggc ggatgctctg cggtgtgttt accatcgaaa gacttcttta aataatagga
    11281 gcaatcctat ggacaaaggg aagccaaagt aaacttatat gacctaactc ttaaaatata
    11341 taaataatat ttttaggagg acacaaataa tgtgtggaat agttggatat ttaggaagta
    11401 gaaaggcagc agaagttata gtagaagggc tttctaagct agagtacaga ggttatgact
    11461 cagcaggagt agcagttaat agttctaatg aaaaagaact taatattaga aagtttaaag
    11521 gtagactttc tgtacttgca gaagacttag aaaagaatcc tattgatgga aatttaggta
    11581 tagggcatac gagatgggca actcatggag aaccatctga tgtaaactca catcctcatt
    11641 ttaatcaagc caaaacaata gcagttgttc ataatgggat aatagaaaac tatatggaaa
    11701 taaaagaaga attaatttct gaaggtgtta agtttgaatc tcaaacagat acagaggtaa
    11761 tagcacattt agtagataaa tactatgagg gtaatttatt agatgctgta tacaaaacta
    11821 tatcaaaatt aagaggagct tatgcattag gtgttatatg taaagaacat ggaaatgaat
    11881 tagttgcagt aagaaaagat agtcctcttg tagttggtgt tggtgaaggt gaaaacttta
    11941 tagcatcaga tatacctgca ttattaaaat atactagaga tgtttatttc ttagaaaatg
    12001 gagaagtagt tcatctaaaa gacgaaaatg taacagttta tgactctaat agaaatcttg
    12061 ttgaaaaaga agtatttcat gtaacttggg atgtagaagc tgcgtctaaa ggtggatatg
    12121 actactttat gtcaaaagaa attcatgagc aaccaacagg agtaagagaa actttagaaa
    12181 gaagacttga tgataatgga aatataattc tagacagtat aaatatttct aaagaagact
    12241 tagaaaaaat aaataaagtt tatatagtgg cttgtggaac agcatataat gctggattac
    12301 ttggtaagta tgccatagaa aaatttgtaa atataccagt aataactgat atagcatcag
    12361 aatttagata tagcgaccca tttgtagatg aaaattcatt agtaatatta gttagtcaat
    12421 ctggtgagac agcagatact ctagcagtat taagagattc aaaggctaaa ggagcaagaa
    12481 tactttcaat aactaacgtt gtaggttcat ctatagcaag agaatcagat gatgtattct
    12541 atacttgggc aggacctgaa gtagcagttg catcaactaa ggcatatact actcaaataa
    12601 cttctttata catgatagct ttagactttg ctatcaaaaa aggaacaata actagagaat
    12661 tttatgatag tatgatttct aagatgaaag aaataccatc aaaaatacaa gaaatactag
    12721 acaatgaaga atatataaaa gaagttgcta aaacagttgt tagttctgaa catgcattct
    12781 atttaggaag aggtatagac tatagcttag caatggaagg ttcattgaaa ttaaaagaga
    12841 tttcatatat acatgcagaa gcttttgcag caggagagct aaagcatgga acaatagctt
    12901 taatagaaaa aggaactcct gtaattgcca tagctactca agaaaagtta tttgaaaaaa
    12961 tggtttctaa tatggaagaa gtaagagcaa gaggagctta tgtagtagca atagctcaaa
    13021 gccataataa ggatgttgag aaagctgctg ataaaataat ctatatacca aattcagatg
    13081 atattttatc accaatatta gcagttgtac caatgcaatt acttgcttat catgtctctg
    13141 tactaagagg atgcgatgta gataagccaa gaaatctagc taaatcagta acagttgaat
    13201 aaaaacagat taaaaattaa atagataata tttattgaaa agaactcatc ctgttatttg
    13261 tattttatag gatgagtttt ttagataaat attaaatttg ttttgttttt gctataataa
    13321 attttataaa aagattgata ttaaatcatc tgtaaaatga taaatatata gaccatacca
    13381 ggtataggga acgataaata tagttcatat aaaatatagt gagtacttaa taaacatata
    13441 gtcaatatca gataaaaaaa ataatagctt atgagaaaaa ttaaaataca aggtattagt
    13501 aaccttgtga taagataaag tgagtagttt aaaataagaa tataaggaac tatttataaa
    13561 agaatataat gaagctaata gagtataaga aaattacttt attttagtaa aataatttca
    13621 aataaaaatt tttttaaatt gggagtataa attatgacaa atgattttaa aaaagaaaag
    13681 aaagaagatt attttgttaa tcttaaggca atatctactg aagttttaca agaaaaagtg
    13741 caagataacg cttgggttat agttgatact cgcttaaatg atgcttataa tggctggaag
    13801 ttagatggag taaaaagagg tggacatata aaaggagcag tagatttttc tgctaattgg
    13861 ttaagtgtat actcagatag aaaagatgaa gtgttagaac aagcattgaa aactaaaaga
    13921 attgatttag ataaaaatat agtattgtat gatgcaaatg gaaaagatgc tttggttgta
    13981 gcaaattatt tatctaaaaa aggatataaa tatctatata aatatgatat taaacaatgg
    14041 gcagacgacg aaaatcttcc aatggaaaga tataaaaatt atcaaatgat agttcctgct
    14101 tttataataa aagatatatt agatggaaaa attcctgaga catttgaaga ttcaaagaat
    14161 ataaaaatga ttgaagcgag ttggggaaaa gaatcgtata caaaagggca tatacctaca
    14221 agtgttcatg taaatactga tattatagaa cctcctccaa catggatgct tgataatgat
    14281 gataacttaa ctaagtttgc tttagactat ggattaacaa aggatgatac tgtaatagtt
    14341 tcaagtagta cacctatggc atcttataga ctagctgtta tattgagata tataggagta
    14401 aaagatgtaa gagttttgaa tggtggaaca aactcatggt tatcagcagg atatgaatta
    14461 gaatttatta gtaatccaaa acattcatgt actaattttg gagcagatat accagttaac
    14521 tcacaattaa ttgttactac atctgaatta agacaaaaac taaaagaaaa aaataagttt
    14581 atactagtag ataaccgtac ttgggatgaa catataggaa aagtatctgg atatacatat
    14641 tatgataaaa aagggcgtat accaggagct ttatatggac attcaggtag tgatagtgtt
    14701 tcactagaag aatatcgtaa tattgataat acaatgagaa ataaatatga gattttagaa
    14761 atgtgggaca aggaaaatat agatgtgaat aaacagctta tatttatgtg tggaagtgga
    14821 tggcgtgctg ctgaagtatt aacatatgca aatgtcatag gagtggaaaa tacctccctt
    14881 tatagtgatg gatggatggg ctggagtctt gataattcaa atttaattga agtgggagaa
    14941 cacaaataaa gtttttgaaa gtgcaataga gttgtttaaa acaaaggtgt ttttgattta
    15001 ttaggaagag tgtgtaaatt gtgtattggg aagtgtactt aggtatgttc atttggagct
    15061 atggaaattg acaaaaaagt attatctgtt tattttgttg gtaaaatatg aatagattat
    15121 agatttaagt atagactaag taatttatat tacagaagag aatatataag aattaatgca
    15181 agatgtattt gatacatata agaaattggc aagtccagga gaaggataga gaaaattgag
    15241 attgaagagt ttgaaagaga ttattagatg aaaaatacaa aaatgtataa aaatacatat
    15301 tgagaaagta tatctctctt aaatttgtta ataattctat tatacagaaa aacatattta
    15361 agggggattt tttactatga aaaaagtaaa attagctata agctttttta tattaatgat
    15421 tataggaatg acaatatctt atgcagatac aagtataaat actagataca atagattaag
    15481 taaagctctt gaaatatcag aagcaaattt taaattttat aatgttaaaa ttaattctgt
    15541 tataaatcat aatttatcaa ataaagaatt tcataatatt tttatagaaa taattaacaa
    15601 tctaaagttg gataaaaaag gaataaattg gaatcaaaaa gggtctggcg ataaaataca
    15661 attatgtgct actataaaag gtagcgataa agaaatttct ataaaaggaa taaataaaaa
    15721 taacaaagaa agttacatag tagttgacat attggataac aaagtatata aacataaaga
    15781 ggttatttat agtaacgtag aaaatgtgtt aaataaatat tcatctcaag tagatgtgtc
    15841 tgcttgtatt gttggagaat acacaaaaag gttacaaaac aacaaatatg atgatatttt
    15901 acaaaaaata ttatataata tgagtgctaa gcaaatagat gaagttaaag acgtaaactt
    15961 tttatctata acagcatata gtaaagtatt aaatgattat gaattagaat atttagggga
    16021 aaaaattaat ttaaatatag gaattaaata taatgaggat gacggaaaaa cactcatata
    16081 tattgccaca ccaattataa aattagatta ttaattatga ggagatcaaa aaatatggct
    16141 aagataatag taaaaaagag taatccactt aaaggtagtg ttaaaataga tggtgcaaaa
    16201 aatgcagttt taccaataat agcagcgact ttattagcaa acggaaaatc aacattaaat
    16261 ggagtaccaa atttaagaga tgttcatgtt atatcagatt tattaagaca tgtaggagca
    16321 gaagttgaat ataaagaaaa tacacttact gttgatgcaa gcaatataaa aacttgtgaa
    16381 gctccatatg agcttgtaag aaagatgaga gcttcttttt tggttatggg accattgctt
    16441 gctagattta atagtacgaa aatttctatg ccaggaggat gtgctatagg aacaagacct
    16501 atagatttac atttaaaagg atttaaagcc ttaggtgcaa agatagaaat ggaccatggt
    16561 tttgttgaag cagcaacaga aaagttagta ggaaataaat tatatttaga tttcccatct
    16621 gttggagcaa ctgaaaacat aatgatggca gcttctttag cagaagggac tacaataata
    16681 gagaatgcag cagaagagcc agaaatagta gatttagcaa acttcttgaa cgaaatggga
    16741 gcagatgtta aaggtgcagg tactaatact ataaaaataa aaggtgttaa agagttaaaa
    16801 ggagcagaac ataatgtaat tccagacaga atagaagcag caacttatat ggttgcagca
    16861 gctatgacaa aaggtgatat aactgttgaa aatgttttaa tggagcattt aaaaccagtt
    16921 gtagctaaat taagagaagc tggttgtgaa ataacagaaa tggacaattc tgtaagagtt
    16981 gtaggtccaa aagtattaaa accaatagat ataaaaactt taccacatcc aggatttcct
    17041 acagatgttc aagcacaatt tatggctatg cttactgtag ccaatggaac tggtgtagtt
    17101 atagaaactg tttttgaaaa tagatttatg catgttgctg aatttaatag aatgggtgct
    17161 aatataaaaa tagatggaag aagtgcggtt gttaatggtg tagatgagct acacggtgca
    17221 gcagtaaacg ctactgattt aagagcaggg gcagccctta ttttatgcgg tcttatagca
    17281 gaaggagaaa ctcaaatagg agaaatatac catatccaaa gaggttatgt tgatatagat
    17341 aagaagataa cagcactagg tggtcaaatc gaaatagtag aagattaata attggtttat
    17401 agaagaaagt tataaattaa tagggttgtt catatactta aatacaaggt tttaaaagct
    17461 aaggaggaga gtatatgaag aacccattgg ttgttttgtt aggatttgtg acttgctctg
    17521 tgttagttcc atcacttata actttagttt cttataaaaa tgtagaatta actgaaaaac
    17581 cagagagccc agtatctata aacaaaacta ttaaaaaaag tgatattgaa gacaaaggta
    17641 ataaagaaga aaaaaataca gtgaactatg aaactgtaaa taaaaaagca ccaattatca
    17701 atgtatataa tcatataaca gggaaaaccg aaaagatgga catggagaac tatttatgtg
    17761 gagtactagc tggtgagatg tcttcagagt ttgatataga agctttaaaa gctcaatctg
    17821 tagcagctag aacatatgta gtatataaac aggaacatgg taaatctagt aaacataaaa
    17881 atgcagtagt atgtactgat tataaacatt gtcaagaata taagagttat gatactctta
    17941 aaaaattaaa tggtgaagaa tggattaaga ataaatattc caaaatccaa gaagcagtta
    18001 gaggaactaa aggtcaaata ataacttata atgataaggc gatacttcct ctttattttt
    18061 ctacatcttc aggaaaaaca gaaaatagtg aagaagtatt ttctgcaaaa tatccttatt
    18121 taaagtctgt ggaaagtcct tatgataagt attcccctaa atttgcgtca acacttaaaa
    18181 taagtaacac agattttgtt aaaagtctta gaagggcata tagcactatt gtgatagatg
    18241 tgaataattt aagtaaacaa gtttcaataa ctaaaagaag tgatgccgga actgtagaaa
    18301 aaataaaatt aggaaataaa gaattgactg gaaaagacat tagaactgtt tttaaattga
    18361 actctgcaaa ctttgacata aaatttggag aaggatacat agatttcgtg gtaaaaggat
    18421 atggtcatgg tgttggtatg agccagtggg gagcagaagg aatggcagaa gagggctata
    18481 aatattatga tatattatca cattactaca cagatacaaa aataaaagat atatactaat
    18541 aattgtataa aatgccaaaa acacgtcaat aatccaaatg tagaaatata tttggaggtg
    18601 caaaatgaag aaaaagctgt tagaaaaaga tggtttttat ttatctttgt ttgtatgtgt
    18661 ttgtttatta gcagtaggtg gagtttggtt tacaaataat aatgtagata aattggcttc
    18721 taataaagga attatggaaa atgctaataa agatagtgaa gaggaaatac atttaattga
    18781 aaaagacaag aaagatgcta tccctactgc aacggattca aaacaaaact tagaaaaagc
    18841 taagtcaaaa gaggaaaata aatcgagtac aacaaaatta aattacattg gagataaagt
    18901 aataagagga tattcagaaa aagagcctag ttattctaaa acacttgatg tttgggaaac
    18961 tcataaaggt gtagatatta gttgtactaa aggcaaagaa gtaaaatctc tattaaacgg
    19021 aatagtagta gatgtatttg atgatgaaga atatggacaa tcagtcaaaa taaaaagtga
    19081 caataacatt gtagtagtat attcaaatct agataaaaat gttagtgtta agaaagaaca
    19141 gaaggtaaca gaaggacaat ctctaggtac tgtaggtagt acttctcaaa tagaaagtga
    19201 agaaggtata catgtgcatt tagaggcgta tagtggagaa aaatctatag acccaatgag
    19261 tctaattaag taatagtata acaagtttaa tcatatttgg ttaagcttgt tatatttttt
    19321 ggtgttttta catatatatc attaaagcta ttatgtgagg ggggtaatct ttgagatctc
    19381 atatagagga aagggccata gtggtagcaa aatatatact tgaaaaaaac actacagtaa
    19441 gacaaaccgc caagacattt ggagtaagta aaagtacaat tcataaggat gttacagaaa
    19501 gattgaagga aataaatcca tcccttgcca aagaagttaa aaatgtgctg gacaaaaata
    19561 aatcagagag acatattaga gggggattag caacgaaatt aaaatatgag aaggaacata
    19621 aaaaaatgta ggttaaaaac ctactttttt tattgaatta aattataaaa agaaatatat
    19681 taagtaatta taaatagcaa aataataata ctctcaaaag atttattttc tcttgattaa
    19741 agcgagattt ttgtatatgc tttattatag gagtattaaa ataggcttat aatataatct
    19801 aatattataa ataaaggagt tgaaaaaatg gctggagctg atataggcat agatttaggt
    19861 actgcaaatg tgcttgttta tgttagtggt aagggaatcg ttttagaaga accatctgtt
    19921 gtggcgatag acaaaagaac agattctgtt ttagctgtgg gagaagaagc taaaaagatg
    19981 atagggagaa caccaggtaa tatagtcgct ataagacctt taagagatgg tgtaatttca
    20041 gattatgatg taactgagaa gatgttaaaa tcttttatag ataagatagt tgataaaaag
    20101 ggatttggaa gattttttat gccaagaatt atggtatgtg taccaacagg tgtcacagaa
    20161 gtggaaaaaa gagcagtaga agatgctacg agacaagctg gagctagaga agtatatatc
    20221 atagaagaac caatagcagc tgccatagga gctggtgtag acatatcaca gcctaatggt
    20281 aatatgatta tagatattgg tggaggtact gtagatatag ctgtaatatc tctaggagga
    20341 gctgttgtaa gtgaatctat aaaggttggt ggagatagat ttgatgatgc tatagttaaa
    20401 tatatgaaaa aacaacacaa tcttcttata ggagaaagaa cagcagagaa aatcaagttt
    20461 gaaataggtt ctgcatttaa gagagaagaa gaaaaatata tgaagataac aggaagaaat
    20521 ttaattacag gacttcctag ttctataact ataaattcaa cagaaatgtt ggaagcactt
    20581 agagaatgtg ttgagcaaat agtagttgct actcatgctg ttttggaaaa aacgcctcct
    20641 gagttagcag cagatatagg agatgtcggt ataataatga ctggaggagg ttcattatta
    20701 tatggattag ataaaataat agaacagagg acaggaataa ctgttacaat agcagatgaa
    20761 ccattatctt gtgttgcaaa aggtacagga atagctttag gttcaataga cttacttgaa
    20821 actggtgggt ctttcaaaag aaaataatta ggagagttta gaatgttaaa tatagatgaa
    20881 ataaaaaaat taataccaca tagatatcca tttttattag tagacaagat tacagagcta
    20941 gaagttggga aaagagctgt tggtataaag aatgtaacag ttaatgaacc atttttccaa
    21001 ggtcactttc cagaatatcc tttgatgcca ggagtactaa tagtagaagc tctagcacaa
    21061 gtatgtggag tggcaatgat gtctgtagag gaaaacaaag gaaaactagg tgtatttgca
    21121 ggtatagata aagttagaat caagagagaa gtaagaccag gagatacatt aactatggaa
    21181 gttgaaatga caactcttag aaaaaatata gctaaggcag atgctaaggc atatgtaggt
    21241 gaagaacttg tctgtaaagg tgaattaatg tttgctttag tagaaaaata aaaacttgaa
    21301 atataaaagt aaaaaggtag ataatttgga gtatttaatc agatactcta aaatatctac
    21361 ctttttatat aaagaatttt atcatttagt ttatatttag attaggtgga tactaataaa
    21421 gccaaggcta ttgtttcagc taaatctaat ataaagctaa ggcgtatatt attaaatgaa
    21481 agtttattat tttcatcaat tttatctaca attcctacta tagaataatt tcctatttga
    21541 ggtagttttt taccaacacc ttttccgggc aggataggtc cttctctaat ctgtatatta
    21601 cctatgttac tctgcgaccc caagcaagca tctatagcca agaagttacc ttgtatatgt
    21661 gtatttttta tagtatctaa agactcatat atatttaagg cgtgaatagg gttatctagt
    21721 gtaccgtaaa cggggtattt aaagttactg ttcttaagta ttgttccaac taaagggcct
    21781 aaagtatcac ctatagccct gtctgttcct atgcaaacaa caatcgtatt ttcattaatt
    21841 atagttttta gaactgaact tagcatctgt ataacatcat catcgctgta gtttacttta
    21901 gctaaataca ataggaacac ccccttcaaa aaaatatatg aataaaaagc attaaaaaga
    21961 cctaacttta aatttcagat agatagaaaa ttttatttgt cttacaaaaa aaggaataga
    22021 aaaaatatga ctaaaaatat tgacaaaatt ttaaaaaaat agtaagctag taaagtaaaa
    22081 caaaacttaa atcttgatta ccttatcaag agaggctgag ggataggccc tgtgaagccc
    22141 agcaaccacc caaatgggaa aaggtgctaa ttcctacaag acaaaagtct tgaaagatga
    22201 ggtcagttaa ttagtatgta attacgatta ttaacctctt cttataaagg agaggttttt
    22261 ttattttgag taaatttcta aaattaaaaa taaggtaaaa cctataataa aaattaagaa
    22321 taaataaggg ggaataaaaa tggcaagaca tttatttacg tcagaatcag ttacagaagg
    22381 acatcctgat aagatatgtg accaaatatc agattcaata ttagatgcat tattagaaaa
    22441 agacccacaa tctagagtag cttgtgaaac tacagttact actggtttag ttttagtagc
    22501 aggagaaata agtacatctg cttatgtaga cattcctaaa ttagtaagag aaacagtaag
    22561 agaaattgga tatacaagag caaaatatgg atttgattgt gatacttgcg cagttataac
    22621 ttctattgat gaacaatctg gagatatagc tatgggagtt gatgaaggcc tagaaagtaa
    22681 gactggagaa gagatagaag aagaaataga aaaagttgga gctggagacc aaggtataat
    22741 gtttggattt gcatgtaatg agactccaga attaatgcca cttccgatat ctttggcaca
    22801 taaattatca agaagactta cagaagttag aaaaacaggt ttagttgatt atttaagacc
    22861 agatggaaaa actcaagtta ctgttgaata tgaaggaagt aaagctgtaa gagtacatac
    22921 agttcttata tcagctcaac attgtgaaac agtatcaaat gataaaataa gagaagattt
    22981 aattaatcat gttattaagg aagttatacc agcagaatta cttgatgaag agactaaaat
    23041 ttatataaat ccaacaggaa gattcgttat aggaggacca caaggagata caggtcttac
    23101 aggaagaaaa ataataatag atacttatgg tggatattct agacatggtg gaggagcttt
    23161 ctcaggaaaa gaccctacaa aagttgatag atctgctgct tacgcagcta gatatgttgc
    23221 aaaaaatatt gttgcggctg gtcttgcaga caaatgtgag atagaacttg catatgctat
    23281 aggtatagct agaccattat ctatatttat agatactttt gggacaggca aggtttcaga
    23341 agaaaaactt gttgaattag taaataaaca ctttgattta agaccaggag cgataataag
    23401 agacttagat ttaagaaagc ctctttataa aaaggttgct gcttatggtc actttggtag
    23461 aactgatata gatttacctt gggaaagaac tgacaaggtt gagcagttaa gaaaagatgc
    23521 tttaggtgaa taatttttaa ctaaaaagct gttagaatgt aattttatga ttactttcta
    23581 acagcttttt tattatgagt taaatatttt taataaatgt taatttatca tcatataatg
    23641 aataaacagt atttaatctg gtcaatacat tttatataat actctactaa atttatacat
    23701 attatgggat atatgttaaa ggatggttaa gaatgtgtta actaatgtta aataattaaa
    23761 aatatattga aatatcacaa taatgagtct aatataatct taataaactt acactttaaa
    23821 aataatttta attggggggg agtagtgtat gtcaggcaaa gtaaatatta aaacggttat
    23881 aagttttgct ggagcttatg ttgctactgt aataggttct ggatttgcaa ctggtcaaga
    23941 aatactgcaa ttttttacgt tttatggata tgcgggtatt ataggtggaa taatctctat
    24001 ggtactattt tcatggtttg gagcagaagt tatagataag ggaagagaat tgaaacttaa
    24061 ggagccaata aaaatttatc aagtatattg tggaaaatat cttggaacat tttttgaatg
    24121 gtttggtcca ttgtttttat ttggaacatt agtaataatg attgcaggag caggagctac
    24181 attatcagag tactatggat taaatccata tgtaggtagg attggtatgg caatcgtttc
    24241 cctaataact gtttcattag gtttgacaag gctttctaaa atactaggta atataggacc
    24301 tataataata atatttacac ttttagtagg agcaattagt ttatttagca atattgatgc
    24361 tttatcaaat gctggaaata tggttgatag tttaaatatt aaaactgcta catcaaatgg
    24421 atatttctcg ggagtacttt atacttgtta caatgtaata atagtaataa cattcttgac
    24481 aggaatggga gcttctgcag taaataagaa agatgctgta tggggtggta tagtaggtgg
    24541 agtagcactt atggcagcag ctataatgat gaatttggca ttactttcag acataggaaa
    24601 tatatacaca aaagagatac cagcacttta cttagctgat aagatatctc caataatagg
    24661 tattttattc tcagtagtac ttttactagg aatatacact acagctgtac cattgttatg
    24721 gtcagtaaca aaccgatttg tagaagatga ccaccctaag tttaaaatta taacaatagt
    24781 ggtaagtata ttagcttgta taggaggttt actgccattt gataagttag taggtacact
    24841 atatccatat acaggttaca tgggaatttt aattttacta tgtatgcttt atagaagaat
    24901 tactaaaact gaggggtaca aggagaataa atctgaaata agttagtact gtaatatact
    24961 tatgaaattt aatttatact ctaaatatag agtaactaaa ataaaatagc tatttaaata
    25021 tggtacctgt atttcatggt accatatttt atggatgcag attttttttg tttctgataa
    25081 aatgtataat agttggaaat tacgttaagt ataaaaatat aaaacttttc tacgattatc
    25141 atagttttaa tatataaaat tatactaaca tttaaatgga gcgattatta gtatttttag
    25201 gagataaaaa tggaaaaatt agaaggaatg ataagtgaaa tagtctttaa aaacgaagat
    25261 aatggttata caatagctca cctggtaaat gaaaatgatg aaattgtggt tgtaggatgt
    25321 atgcctactt tggcaattgg agaaagcata gaagttgaag gaaagtgggt aaatcataag
    25381 atttatggga ctcaatttga agtgaatagt tttatgccag taacaccatc atccttagaa
    25441 ggaatttatg tttacttatc ttctggaatg atacatggta ttggtgaaaa aatggcaaaa
    25501 agaataattg ataagtttgg tgtagatacg ttagaggtga tacaaaattc accagaaaaa
    25561 ctacaagaag tagaaggcat agggagtaaa aaagtaaaac aaatagtaaa aagttatgaa
    25621 gaagacagag aattgagaaa tataataata cagctatctc cttttggaat aacaccaaat
    25681 tactgcctaa aaatatataa aaaatataaa agcagtgcaa tagaagttat aaataaaaac
    25741 ccataccaac ttgctgaaga tataagagga attggattta aagtagctga tagtatagca
    25801 agtaaaattg gtatagataa aaactctaaa gatagaattt gtcagggaat cttatacact
    25861 ttaaataaat ctttaagtaa tgggcataca tatttaccag agcatgttct aatacaagat
    25921 tcggaaaaat tattggagct aaatggagaa ataataaaag agtgtgtaat gatgctagtt
    25981 tataatcaaa aaatacatat agagaaagta aacaatgaaa atcttatata ccttatgcca
    26041 tactatttag ctgaaaatgg agtatgtagt caaatagtaa aattatcaca gtatgaattt
    26101 gaagacttaa aaatagatat agataacgag attaatgttt tagaagaaga taagaaaatt
    26161 aagttagcag aaaaacaaat tttagcagtc aaagaatctg ttaatagtgg agtattaatt
    26221 ataactggtg gaccaggaac tggtaaaaca actaccatta atgctatcat agatatattt
    26281 gaaaataatg gtaaaagtgt gactttggca gctccaacgg gaagagcagc aaagagaatg
    26341 agtgaaactt ctaataaaga agcaaaaact atacataggt tgctagaaat gggattttca
    26401 acagatgatg atttaacttt ttttaaggat gaagaagacc caataaattc agatgtaata
    26461 attgttgatg aggtatcaat ggtagacatt atcttaatgt acaatttact tagagctata
    26521 aagttaggaa caagagtaat tttagttgga gatagtgacc aattaccttc tgtaggtgct
    26581 ggaaatgtac ttaaggatat gattaattct aatattataa atgtagttaa attaaatgaa
    26641 atatttagac aagcgcaaga aagtatgata attgtaaatg cccataagat aaacaatgga
    26701 gaaccacttt atctaaatac aaaaggtaaa gatttctttt ttataagaaa atcaactaat
    26761 gaagaaattt taaatgaaat aataggattg gttaatgaaa gattacctaa attttataaa
    26821 gttgataaat taaaagatat acaagtttta tcttcaatga gaaaaggtga attgggagtt
    26881 actaatctca atatagagtt acagaagtat cttaacaaaa aagaaaaatt taaagttgaa
    26941 gaaagttttt ctaaaagatt atttagagtt ggcgataagg taatgcaagt aaaaaataat
    27001 tatacaaaaa aatgggaaac agaagaccaa aaagaaagtg gagaaggtat ctataatgga
    27061 gatataggat atgtttatca catagataaa gataagaaaa ctatttatat attatttgac
    27121 cagactaaaa ttgtatcata cctatatgat gaattagatg aaattgacca tagtttttgt
    27181 acaacaatac ataaaagcca gggaagtgaa tttccagttg tagtattgcc aatagcgtgg
    27241 gctcctccta tgttacttag ccgtaattta ttatatacag cagtaacaag agcaaaaaaa
    27301 ttagttgtat tagttggaga tgtgaaatat cttgaatata tgataaaaaa taatagagtt
    27361 aatcaaaggt attcaaattt aggatataag ctaaataaat ttaaacaaga agggttgttg
    27421 atagaataaa tatgaaaata tgcaatgata attttattaa gaattttaaa aatatgatta
    27481 ataaatgttt ggattttata tatcctgaga atataagttg cataatttgt gataaatcca
    27541 taaagaaaac aaatacttat tcaatatgta aaagttgttt taaagaaatg aattttatac
    27601 aagatggttg catgaagtgt ggaaaaccaa taatacgtca ttcaattgaa aaagaattta
    27661 ttgaagagtg tagttattgt tttaataaag acttttattt tgataaatca atatcttgta
    27721 ttgaatacaa tgatgtgaca aaaaagatgg tgttagggct gaagtataac caaaaaacct
    27781 ttatggctaa gtatatagct caaataatga aagaaaaatt atatttagaa aacataaaat
    27841 ttgattatat attatttgtt ccacttcata aaaaaaggct aaataaaaga ggttttaatc
    27901 aggcacaaaa aatagcattt aatttaagta aaatagtaaa tattccatta ttagattgca
    27961 taagtagaaa aaaatataca agaatgctat ataaattgaa taagaaagaa cgaaaagaag
    28021 aattaaaaaa tgtatttgtt gttaaagaaa atgttaaatt aataaataat aaaaatatac
    28081 ttttaataga tgatatattt actactggtc taacaacaaa cgaaatttct aaacttttaa
    28141 agttatcagg tgctaataag gtttttgtat tgactctact tacaaaagcg aatgataatt
    28201 atattatgga ataatcttat atattgacaa ttttagttta aaatattaaa atgaataagt
    28261 gatatttagg tctgtggttg aaagtccaag ccagtcgcag gcaaagggat ccacgtaagt
    28321 taacactaaa aattgggtta atgatcatgg tgcggcttag aagtaagacc taccgataat
    28381 aaaatcgaga gagagtagta gtgcggcgaa cccaagcgaa ccctccagta ggcgagtgtg
    28441 gggtcaaaaa ccaggtcagc taaatatcat attaaaagag agctagcata cctttatgta
    28501 tagctctttt ttatatataa taaatttagg ttgagtcata aagaggtgat atgtttgaat
    28561 aaaagacaag aaaatttatt aacaacattg ctattaaaag aagagtttat aaatgttaat
    28621 aagattgcca atgattttga gtgttcagaa aggacaataa gaaatgattg caaatatatt
    28681 gatgaatggt tatctacttt ttgtaatgct tatatcaaaa gaaaacctaa tattggaatt
    28741 aaatttagtg gagatggaac agacaaaata ctggtaaatc agaagttgcg aggtgaagtt
    28801 aaaagagtaa atagtgagct tcataagcaa gttgagatat taaatttact actttgtaat
    28861 aataaaaaag ttactttaaa tgatttatct aataagttgt acataaataa aaatattgtc
    28921 agagaagaaa taagtaaatt atcagtagca ttaaataatt ataatttaaa tatctcgact
    28981 aaaaaaggca gtggtatata tattgaaggg gatgagaaag acataagaat aatgttagta
    29041 tcattcttat ttaaatatat agataaatac agattaaaca tagatgaaat agagtacttc
    29101 catatagtag atataataat tgtaaaaaac ataatgctta ctatagagga ggatatggat
    29161 ataagactta cagatatatc attcaaacaa ttgatgctat ttttgcttat aaatataata
    29221 cgaataaggc tgggaaattc tttaaaagta tcaaatacta agaaagagct taagctaaaa
    29281 atgcttatat tggatataga agatgaattg aaatctaatt tatccatagt attaaattat
    29341 gaagaaaaat tgtttataga atctttaata ttgggtatga acaaacaaat aaatagtaat
    29401 aatattaaga aacctttata tctaaatgaa gaattagcaa gttatacaaa aaaaattata
    29461 aatttagtat cagaagaatc aggaataaat tttaataatg atatattact ttatgaacaa
    29521 ttaatatgtc atttgaatgt tacaatgcat caaatgaaaa gcaatgttta cttagaaaat
    29581 ccacttttag ataacataaa aactaaattt tgttttttat ttacagtaat atcaagttca
    29641 atagaaattg aattaaaagg aaaacaaata acggaagatg aaattggtta tcttacactt
    29701 cactttcaaa cctctctaga aagaaaatac agcaaaaggg aatcaaataa aaaggcaagt
    29761 attgtatgtc catttagttt tggagtaagt atgctattaa aagtaaagat agaaaagaga
    29821 tttgataata taaaaattat tgaaacatta agagaggaag atttaaaaag agataacttc
    29881 aataagacta tagattttat aattgcattt caagagtatg aaaatatcca aaaaccaatt
    29941 tttataacaa caccattatt tactgatgag gatgagaata aacttaaaga gttcacaaac
    30001 aaaataaaag aaaaagacac ttcatataaa cttatgaaca gattaatgat gtctgattat
    30061 ttaataagag agttagaaca tgatgatatt tatgaagcta taacatattt aactaattta
    30121 ttaattgaaa aacattatgc agaaaaagag tatttacaat ctattataac aagagaaaag
    30181 tcatatccaa ccaatgttgg aaaaggaata ttattccctc atggagacat gaaatatata
    30241 aaacaatctg ttttatgttt tgcaaggtta aaaacaccaa taaaaattag aaatggaaag
    30301 gatataaaga ttatactttt gttagcatat aaaaaagatg atgatagaaa agtatttaga
    30361 gaattattta aagaaatatc taatttaaca gaggatgaaa atatgctaga tattctaagt
    30421 aaatgtgaca ttgaaaaggt aaaagatatt cttatataaa attcatagtg aactatggat
    30481 aagcacaaaa ttttccatgt gatggaaaaa gttgtgcatg tttttttgtt tttataagat
    30541 attatatgtt tgtaaggtat aaataatcta aaagtagaga agcaacttag gaggaaaaaa
    30601 tggaagaaat agttttaaag attataattc atgctggaaa tgcaaaatct atgctttatg
    30661 aagcacttga ctatgcaaag gaaaacgatt ttaaaaaagc agatgaatta attgaaaatg
    30721 caaatgaaga aattttaaaa gcacataaag tacaaactga acttatacaa aaggaagctg
    30781 ggggagataa atcagatata tctattttat tgattcactc tcaagaccat ttaatgactt
    30841 gtatgagtga gagaaacctt ataaaagaaa tgattatgtt aagaaaagaa attcaaaaat
    30901 taaaataaaa aaattaaggg ggatttaaaa aatgaaaaga aaagtatatt tattttgtag
    30961 ctttggtatg tcaacaagtt tacttgcaga taaaatgcag aaggtagcag atgaacacaa
    31021 tttaccaata gaagtagagg catttccgat agcagaaatt gacaaaatag ttgaagaaaa
    31081 aaatccagat tgtatattat taggaccaca agttaaatac atgctaaagg agttaaaacc
    31141 aaagtttgaa gctcaaggaa aacttataga tataatcaat gaagttgatt atggaactat
    31201 gaatggggaa aaagtattaa agcttgctat aaagctaata aaatctaaac aagcgtagaa
    31261 ttatagtaaa aaataatagg aaatgagggt ggatagatga atagattgga aagaatactt
    31321 atgccattgg ctgaaaaaat aggtaaaaat aaattattaa ttgcaattag agatggtttt
    31381 ttagtatcat caccattatt aataataggt tcattatttt tattagtagc aaattttcct
    31441 ataaaaggat ggaatgaatt tgtaggtcaa atttttggtc cagattgggc tgtaaaattg
    31501 caacaaccaa ctgtagcaac atttgaagta atgactctac ttgcagtttt agggattgga
    31561 tattcttatg caaagcaaat agatgtagac ccaatagcat cagcagcagt tgcaatagtt
    31621 gcctttttta taataacacc atttgtaata ccatatacac cagaaggaac agaatccgtt
    31681 tacatggtaa caggtatacc actaggttgg atgggttcta agggaatgtt tgtaggtatg
    31741 ataacagcaa taacctctgt aaaattattt gctgcagttg taaaaaaagg atggacattg
    31801 aaaatgccag atggagttcc tccaactgta tcaaaatcat ttgcagcatt aataccaagt
    31861 gcaatagtta tggtagtttt ctttttagtt aagatagctt ttgaagctac accatatgga
    31921 agtatacatg aatttatatt taagttttta caaatgccat tattaaaatt aggaaatagt
    31981 ttaggtgcta tggcaatcgc ttatatattc ttacatttat tctggttctt tggaataaat
    32041 ggaagtagtg ttgttggggc tgtgtataat ccaatattaa aaattctatc agctgaaaac
    32101 ttagctgctt ttcaagctgg ttcaaaaata ccaaacataa taacaggtca attccaagat
    32161 atgtttgcga catttggtgg agcaggtagt acactatcat tagtcatagc tatgttatta
    32221 atatgtaaaa gtaaacgtat aaagtcaatg ggaaaactat caattttacc aggaatattt
    32281 ggtataaatg agccattgat atttggtcta ccaataatgc ttaacccaat actattgata
    32341 ccatttgcaa tagttccaac aataaatata ataatagctt acttctgtat gtcagcagga
    32401 ttagtgcctc ttacaaatgg agttcagtta ccgtggacaa ctccaattat attctctggt
    32461 tttttaacaa caggatggca aggtgcagtc ttacaattag tacttcttat actaggaata
    32521 tttatgtata taccatttat aaaaatgcta gataagcaat acttgagaga agaaaatgaa
    32581 actgttgaag aggaagatga tgatatatct tttgatgatt tagtattata ggaggaagat
    32641 tatgaagaaa atagttatga tattggacca aatacaagct ggagctggag gaaaagagaa
    32701 aagtaatata cctcctgctg gaaaatcaag cccattagga ccaggtgtaa tgatggagca
    32761 atttttaaat gaatctaagg taatagctac cttattttgt ggggatgaat tttttgtaaa
    32821 taatcaagaa gaagtaacga gtaagatgat agctatggta aaaaaattaa accctgatgt
    32881 agtaatctgt ggaccaagct ttaattacga aaacttttct aagatgtcag caatactgtc
    32941 taaaaatata aatgataaaa cagatatacc agcttttgca gctatgtcag aagaaaatat
    33001 agatgtgata aacgaatata aaaatgacat atgtatagtt aagactccca aaaaaggtgg
    33061 aattggtctt aatgattcat taaataacat atgtaaattg gcaaaagcaa tagcaaataa
    33121 agaagatata actttgatga aagaagaatt ttgttattaa taagagtatt aattattagc
    33181 aagtttaaat attatactat ttataataag catacattag taaaatctat ataatttaag
    33241 gaggggaatt ttaacatgtg gggaatgata gcgacatgga gaatggccct agaaggaata
    33301 actgaggcat cagaacattt agaaaaaggc atggaagcag gtgatgctgt agagcttgct
    33361 gtaagaagag ttgaagacta tccattctat aaatcggttg gatatggtgg acttccaaat
    33421 gaaaattgtg aggtagaact tgacgctgca tttatggatg gtaacacatt agatattggc
    33481 gcagttgctg gtataagaga ttattctaat cctgtcagca tagctaggaa gttaagttat
    33541 gagaaggtaa ataatttttt agttggaata ggtgctgaag attatgctca taaaaatgga
    33601 tttgaaagaa aaaatatgtt gactgataga gcgaagttac attataaaaa gagaaaaaaa
    33661 gagactttag acaaaggatt aagcccatat gctggtcatg atactgttgg tatgatatct
    33721 ttagacaaaa ctggaaaaat gtgtgcagct acatcaacaa gtggattgtt tatgaagaaa
    33781 agaggtagaa taggagattc tgcactatct ggttcaggat tctatgttga tagtagtata
    33841 ggaggagcta cagctactgg tttgggagaa gatttaatga agggatgtat atcttatgag
    33901 atagttagac ttatgaaaga agggaagcat ccacaagaag catgtgatat tgcagtaaat
    33961 gaacttgata aacagcttat cgaaagaagg ggaaaagctg gtgatttatc attagttgcc
    34021 atgaataata aaggtgaatg gggagtagct acaaatatag ctgattttac tttttcagta
    34081 gtaactaaag aagaatctcc tactgtatat atttcaaata gagtagatgg aaagactata
    34141 cataaggtta tatcaaatga gtggatggaa gcatatgagg ctagaataaa agcaccaata
    34201 gaagtaagtg agtaaagtag tggttacata attaaaatag agttttataa taaggagatt
    34261 tttatgaata tcataagtaa taaaatagat gagttaaaag aagatttatt aagtgatatt
    34321 atagatattg taaaaatacc tagtgtcaaa ggggagtcag aaaatggctt cccttttggc
    34381 gaaaaagtag gggaggcact taataaagca ttagaaatat cagaaaaatt gggatttaag
    34441 gttagaaact tggataatta tattggttat gcagagcatg gagatagtga tgattatgtt
    34501 tgtgtaattg gacatgtaga tgttgtacat gaaggagatg gttggaagca tcatccttat
    34561 aagggagaag aaactaatgg aagaatttat ggacgaggag tactagacaa taaaggacct
    34621 ataatgtctg ccttatatgg attatatgct attaaagaat taaacttaaa attagataag
    34681 agagttagaa taatatttgg tacaaatgaa gaaagtggat ttgaagatat accatattat
    34741 ttagaaaaag aaaaagcacc tattatggga tttacaccag attgtaagta tcctgttgta
    34801 tatggtgaaa aaggcatggc aaagattaga ataaaaagta aaatcaatta tgaagaagat
    34861 gtatacctag gttttataga aaatatgtct gaaaatgtgc ttgttacata taaagagctg
    34921 aatatagaaa atagtgatac tatattagat ataaaggtaa aatacgattt tagttataaa
    34981 ttgaaagatg tattggatga aataaaagct agttttccaa atagtatcga tatagaggta
    35041 atttctaatt ttaatcctgt atattttgat aaagagagta atcttgttaa aaagcttcag
    35101 ctagcttatg aaagggttac atcattagat ggaactccag taacaactaa tggaggtacg
    35161 tatgcaaaag taatgccaaa tatagttccg tttggaccct catttccagg acaaaaagga
    35221 atagctcata atcctgatga atacatggat atagaagata taatattaaa tgcaaagata
    35281 tttgcaaatg caatatatga attagcaaag gagtagttat gttagaaata ataggaatgt
    35341 cagtagaaga cgctaaaatt atagaagatt gtggtgcaga tagaatagag ttagttagtg
    35401 ctttaactga aggtggattg acaccaagtt ttggtcttat agaaagtgtt gttaacagtg
    35461 taaagatacc tgtgaacgta atgataagac atcatgcgaa aagttttgta tacagtaaag
    35521 aagatataag tataatgcaa aaagatatag gtgtggttaa agagattggt gctaatggag
    35581 ttgtatttgg tgtattggat aaaaacaata atatagatga gaaaaatcta aatgttttat
    35641 tgaaatgttg tgataatctt gatgttacat ttcatagagc catagatgaa tcaaatacaa
    35701 tagatagtgt taaaattttg aaggattatg ataaaattac gaatatatta acatcaggag
    35761 ggaaaggaag tatagttgat aacatacaaa tgataaagaa tatgatgctt agttctaatc
    35821 acataaaaat tcttttaggt ggaggtctta attttaataa tatagaaaag ataaaggaat
    35881 tgactaaggc aagtaatttt cattttggta cagcgattag aataaataac agtccttttg
    35941 aagatataga tagacaaaag cttaaacaac tcgtaaatat aatttcaaga tagtatatga
    36001 atataaaata cttagtttaa ataaagagag taagttaatt ataatttggg tatatgaatg
    36061 ttaataggta ttaaatatga aattattgtt gagtatgctt tataactttt aagtagtttt
    36121 aaatataaat aatgaaagaa aagatagatt atggaggttt tagagggttt atatttatta
    36181 aaaaattata aaggtatatt ggcatataat acacataatt tcctaaaatt accatcttat
    36241 gacatgaatt cacatattaa taaacaatta atggagattt ttgtggatag aaataggagt
    36301 aaaaatagct ttaaataaac aaaaacaaga gttattaaca gttttatcca cattatccac
    36361 aggtgtttgt aataatatta atccacataa gtatcaatgt aactaaaaat gataaataat
    36421 tctatcaatt gaatagaaaa aatcataaaa gtaaataata aaaagaggat tatgagagtt
    36481 cgtgtagaat atattattaa agtataaatt ttcttatact ggcataattg aagggagatg
    36541 tatttatgaa cataattata tctggaaaac aaatcgaatt aactgatgca ataaaaaata
    36601 aaatcgaaac taaactaagt aagttagata attacattca tccagacact gatgtaaaag
    36661 ttacagtgag tgcgagaaaa gcaagacaaa aaatagaagt aacaatagct actgtaaatg
    36721 gtcctataat tagagcagaa gatatgcagg aaaatttata cacagctata gatgttgtat
    36781 atgataaatt aagtaaacaa ttaaaaaaat ataaaaagag attacaagat aaacataaag
    36841 acaacaagag tataagattc caagatgcag agataaatct agctgatgaa caagaggatt
    36901 atggggatga aaatcaagaa ttagtaattc aaagacgtaa gaaatttagt gttaagccaa
    36961 tgagtgaaga agaagctgta ttacagatgg aattaatagg acatgatttt tatatgttca
    37021 agaacataga ttcagatgaa atagcagtag tttataagcg taataatggt ggatatggta
    37081 taatagaaca tgaataaagc aatttagatt taatcatatt agctatcgat aaataaatta
    37141 tcgatagctt tttaaattaa tattaaaagt atagttttta tggtaaaatg aataatagta
    37201 caataaagaa cgaggagaga tgtaaaatat gagctttatg gataatttat tcaacatggc
    37261 agataaaaaa gaattaaaaa agttcaataa aactgttgat ataatagatt cattagaacc
    37321 taaatttgaa tctatggcag actcggaact taaaaatatg acaaatatat ttaaagaaag
    37381 attagcaaat ggtgaaagta tagatgatat acttccagaa gcttttgcag tagttagaga
    37441 agtttctaag agagtgttag gacttagaca ctacagagtt caaatgattg gaggtatagt
    37501 actacatcaa ggaagaatag cagaaatgaa aacaggtgaa ggtaaaactt tggttgcaac
    37561 tgctcctgtt tatttgaatg cgcttactgg aaaaggtgta catgttgtaa cagtaaatga
    37621 ttaccttgca aaacgtgata gagaccaaat ggcaaaaatc tatgagtttt taggaatgag
    37681 tgtaggcgtt attatacacg gtcaaaatcc aaaagttaga aaagaacaat atgattgtga
    37741 tataacttat ggtacaaata atgaatatgg atttgactat ctaaaggaca atatggtaat
    37801 acacaaagag caaagagttc aaagaggatt aaattatgct atagtggatg aggttgactc
    37861 tatactaata gatgaggcta gaacaccact tatcatatct ggacctggag acaaatcaac
    37921 tcacttatat tcagatgcaa acacatttgt tttaacctta aaaccagatg attatgaatt
    37981 agaagaaaaa gataaggctg tatctctaac agcatcgggt atacaaaaag cagaagtgta
    38041 ttttaatgtt gataatataa cagatatatc tcatacagaa ttataccatc atataaatca
    38101 agctttaaga gcacatgtaa taatgaagaa agatgttgat tatgttgcta aagatggaga
    38161 aatagtaata gtagatgagt ttacaggtag acttatgttt ggtagaagat attcagaagg
    38221 tttacatcaa gcaatagagg ctaaagaagg tcttaaaata caaagagaat ctaaaacact
    38281 agctactgta acattccaaa actactttag aatgtacaaa aaactttctg gtatgactgg
    38341 tacagcaaaa acagaagaag aagagtttaa agcaatctac aaaatggatg ttttccaagt
    38401 acctactaat aagcttatga taagggaaga cttaccagat tgtgtataca aaagtgaaat
    38461 aggtaaattt aatgctgtag cacaagaaat aattgaaagg cacaaagtca atcaaccaat
    38521 acttgtaggt acagtatcaa tagaaaaatc agaattatta tcacaaatac taaagaaaaa
    38581 gggcataaag cacgaggtat taaatgctaa gcatcatgat aaagaggcag aaataatagc
    38641 acaagctggt agacttggag ctgttacaat agctactaat atggctggtc gtggtacaga
    38701 tatagttcta ggtggaaatc cagacttttt aactaagaga gaaatgagaa gaaatggatt
    38761 taaagaagaa atagtaaata gagtagatac tccaatagaa ggtatacctg taaaaggtaa
    38821 tgaaattcta tttgaagcta gagaagagta tgaaaaacta tttgaaaagt ttaagcaaca
    38881 aacacaagaa gaacaaaaac aagttgtaga agcaggtgga cttgctataa taggtacaga
    38941 aagacacgaa tctcgaagaa tagataacca gttgagaggt cgtgctggac gtcaaggtga
    39001 cccagggagt tcaagattct atataggtct tgatgatgac cttatgagat tgtttggtag
    39061 tgatagaata tctggtattg tagataaaat aggtcttgaa gaagacatgc cgatagaaca
    39121 tagaatatta tctaagtcta ttgaaggagc acaaaagaaa gtcgaaggta aaaactttgg
    39181 aataagaaag catgtacttc aatatgatga tgttatgaat aaacaaagag aaataatata
    39241 tgcagagaga aaacgtgtat tagaaggtga agatttacaa gaacaaatac aatcaatgac
    39301 tcattctata atagaagaag cagttactct ttatacacaa gataaaggat ttgatgaaga
    39361 aggattcaaa gaacatatgt ataatttgtt cttgccaaaa ggtagcatag aaataccaga
    39421 aatagaaaaa cttaatccag ttgaaataac agaaaaagtt tatgaaatag ctatgaagat
    39481 atatacttca aaggaagaac aagttggcta tgagagaatg agagaagttg agagagtaat
    39541 cttacttcaa gctgttgata accattggat agaccatata gatgctatgg accaattacg
    39601 ccaaggtatt ggtcttcgtg ctgtaggtca gcaagaccca gttattgctt ataaaatgga
    39661 aggttttgat atgtttgatg aaatgaataa acatatcaaa gaagatactg taagatattt
    39721 atttaatata acaatagaaa ctccagtgga aagaaaagca gttgtagatg ttgaaaatct
    39781 atcttctcca tcagatggaa cacttccaac aagtaaaact gttaaaaaag atgaaaaggt
    39841 tggaagaaat gacttatgcc cttgtggaag tggtaaaaaa tataaaaact gttgtggaag
    39901 ataatctcgg aggattaaat gttaaagtta caagagtata gacatagtat ggagcagatg
    39961 gcttcaaatt tagaagaatt gagggtttct ctttgacata gcttcattga tgaaaaatat
    40021 acaaattaat gaagaaaaga tgaatcaaca agacttttgg aatgataatg aagtcgctca
    40081 aagagtactt caagaaaata aatctttaaa agagacatta gaagaatatg aaagcttaaa
    40141 aagcttatta gaagatatag aagtattaat tgaaataggt ttagaagaag atgatgattc
    40201 tgtagaaaga gatatagaaa agtccataga atcaatggaa gaaaaattat ctgaaatgaa
    40261 aataaagact cttctaaatg gagagtatga taaaaataat gctatattat ctataaatgc
    40321 tggtactggt ggcttagatg ctcaagattg ggctcaaatg cttttgagaa tgtatataag
    40381 atggtcagaa agtaagggtt ataaagttaa gcttttagat ataatatcag accctgaagc
    40441 agggataaag acagctacaa ttcttgtaga aggaacaaat gcttatgggt atttaaagag
    40501 tgaaaaagga gttcatagat tagtgagaat atctccattt gacccatcag gaaaaagaca
    40561 tacttcattt gcatctatag atgtaacacc agagttagat gaaaatatag aagtagaaat
    40621 taatccatca gatttaaaga tagacacata tagagcttct ggagctggag ggcaacatgt
    40681 aaatacgact gattcagcag ttagaataac acatatccct actggtgtag tagttcagtg
    40741 ccaaaatgaa aggtctcagc atctaaataa ggacagagct atgagacttt taatggcgaa
    40801 attgatagaa ttaaaagagt tagagcaaaa ggaaaaaata gaagatatac aaggcaaata
    40861 ctcacaaata acttggggta gtcaaattag gtcatatgtt tttcaaccat ataaattggt
    40921 taaagaccat agaacaaatg ctgagtttgg aaatgtagat agtgtaatga atggaaatat
    40981 agacttgttt attaatgaat acttaaaaat gaataaaata gtttaataaa tatgcactgt
    41041 aattaagata tatgtataag aaggttagtg cttaatatgc acttacagca cttaggctga
    41101 ggacgataac cctcagcctt cgttctgttt tgttatactt atgaaaaact aacattagga
    41161 gtgaataaat tggatataaa tcaaatctta aaaaaagagt ttaatcttag agatgaacaa
    41221 ataaataata cattaaaact tattgatgaa ggaaatacaa taccatttat agctagatat
    41281 agaaaagaaa tgactggcga gatgagtgat gttacactaa gagaatttta tgaaaaacta
    41341 atgtatttga gaaatcttca aagtagaaaa gatgatgtag ttagactaat agatgaacaa
    41401 gggaaattaa cagatgaaat aacacaaaat atagaaaaag caaaaacatt acaagaagta
    41461 gaagatatat atgctccata taaacaaaag aaaagaacta gagcaacaat agcaaaagaa
    41521 aaaggattag aaaatttagc attgtcaata ctagagaata atttagataa tatagaaata
    41581 gaggcaaaga attatcttga tgaagagaaa gaagttcttt ctattgaaga tgctctaaaa
    41641 ggtgctagag atataattgc agaactagtc tcagatgatg ctaagattag aaagtatata
    41701 agagaattag ctttaagaga aggtatgata gttagcaaaa gtgctactga tgagaaatcg
    41761 gtttatgata tgtattatga ttatagcgaa gcagtaaaaa gtatggctcc acatagagtt
    41821 ttggcaataa acagaggaga aaaagaaagc ttcctaaagg ttaagttaga aataaataat
    41881 gataaagttt taaattacat aataaacgaa tatgtaaatg ataaaaattt caaaaataaa
    41941 gaagaaatcg taagttcaat agaagattct tataaaagat taattttccc atcaatagaa
    42001 agagaaataa gaaatcattt aacagaaata gctcaagaaa gagctataag tgtatttgga
    42061 aagaatgtta aaagtttatt gcttcaacca ccagttaaag acaaagtagt tatgggattt
    42121 gaccctgcat ttagaactgg atgtaaaata gctgtagtag ataaaaatgg taaactacta
    42181 gattatacaa cagtatatcc aacagaccct caaaatgatg tagagggagc aaagaaagtt
    42241 ttaaaaggat tgattgaaaa atacgatata gatataattt caattggaaa tggtactgca
    42301 tctagagaat cagaaacttt tgtatcagaa atgataaaag aaatagatag cgaagtgcag
    42361 tatgtgatag ttagtgaagc aggagcatct gtttattcag catctgaact tgcaaatgag
    42421 gaacatccag atataaatgt atcaataaga ggagctatat ctatagctag aagattacaa
    42481 gacccattag cagagcttgt aaaaatagac cctaaaagta ttggtgttgg tcaatatcag
    42541 catgatttaa acaaaaagag attagaagaa gtactagatg gagttgttga agattctgta
    42601 aatagtgttg gagtagattt aaatactgca tcatactccc tactagaaca tgttgcagga
    42661 ataagtaaag ctatagcaaa aaatataata gcatatagag aagaaaatgg agattttacg
    42721 tcaagagcac aattgaaaaa agtaaaaaga ctaggacctc aagcatttac tcaatgtgct
    42781 ggatttatga gaatcttaga gggtaaaaat ccactagata atacaggtgt gcatcctgaa
    42841 agttatgata tatgtaaaaa aatgattgag ataattggat attctttaga tgatgtaaag
    42901 aataagaata taggtgaaat agatgaaaaa ataaaagaaa ttggcttgag ggaattaagt
    42961 gaaaaactgg aagtaggaca agttacatta aaagatatca tagctgaaat caaaaaacca
    43021 ggaagagacc caagagaaga aggtataaaa cctatactta gaactgatgt cttaaaaatt
    43081 gaagatatac aagagggtat gactttaaaa ggtacaataa gaaatgttgt agactttggt
    43141 gcatttgtag atattggaat aaaaaatgac ggattagttc ataaatcaga aatgagtaat
    43201 agttttgtga aagaccctat gagtattgtt acagtaggtg atatagtaga tgtaaaagtc
    43261 attggaattg acttaaacaa aaaaagagtt gccttatcaa tgaaaaaata gataagttta
    43321 tgtatggtta tagtacttag attctatatt tgtaaataag attactcgag tgtataaatg
    43381 ttaaaaattt gtaaaagtat atagtaagaa aatatattaa aataagaacg atagtcttga
    43441 aaatcaggag gaaaatgaat gatttttata aaaaatggta aaataaatac cataacaaat
    43501 gggataattc atggagatat acttatagat gaaggaaaaa taatagaaat tggagaagat
    43561 ttgatagctc ctttagatgt agaggtaata gatgctagta ataaacttgt gtttcctgga
    43621 tttatagatg ctcatactca cttaggttta tgggaagatg gtatagggtt tgaaggagca
    43681 gatggaaatg aagagactga cccaataaca ccacaattaa atcctataga tggaattaat
    43741 ccaatggata gaacttttaa agaagctttt gaaggtggaa taacttctgt ttgtacaacc
    43801 cctggaagtg caaatgttat gggtggtcaa tgtatagcta taaagacatg tggaaaaaga
    43861 attgataaaa tggtaataaa aaatccagtt gcatctaaaa ttgcttttgg agaaaatcca
    43921 aagagctgtt atggtcagga tgataaatct cctcaaacta gaatggctat agctgcttta
    43981 cttagagaaa acctaaaaaa agcagaagaa tatttagagg atattgatat gtatgagagt
    44041 catgatgatg aagactgtga aaaacctgaa tatgatataa aaatggaaag tttaatacca
    44101 gttttaagaa gagaaattcc ttttaaggca catgctcata gagcagatga tatgtttaca
    44161 gcaataagaa ttgcaaaaga atttaattta aagcttacat tagaccattg tacagaaggt
    44221 catcttattg tagatgaatt agtggaagaa gggtttcctg taatagtagg gccatctttg
    44281 tcagaaaggt ctaaatttga gcttagaaat ttgacattta atacagcagg aatactttca
    44341 aatgcaggtc ttgatgtatg tataatgaca gaccatccag taataccagt tcaatatctt
    44401 ccaatatgtg caggtattgc agtaaaacat ggtatgaaag aagaaaaagc aatagaatca
    44461 attacaataa atccagctaa gactttagga atagaagata gagtaggctc tatagaagtt
    44521 ggtaaagatg cagacctagt aatttgggat aattctccac tagagattca aagtaatgta
    44581 ctttacacta taataaatgg caaagtagtg tatgagaaaa aataacttga caattattaa
    44641 aaaattaact aatataagag tgtaaggaaa attaaaaaat caaagaagat cttcggggca
    44701 gggtgaaatt ccctaccggc ggtatagccc gcgaactact taggtggttg atttggtgag
    44761 attccaaagc cgacagtaaa gtctggatga gagaagatat ttatggaaga taaataagtt
    44821 tattttagtt tgtttaaact atatccataa aaactcgaag atagggtctt cgagtttttt
    44881 gtttttccta aaaaatataa acatattgat tagggggaaa ataattatgc aaaacacagc
    44941 aaaaagaggc aatatgattt caacaagaac tttagtagta atgtcaattt tatctgcaat
    45001 atcttattta ttaatgttta ttcaagcacc aataccaggt atatttccag atttcttaaa
    45061 aattgactta tcagatattc cagcaatatt cggaggaatg tctctaggac cattagttgg
    45121 atttggaata gttgtagtaa aaaatgtgtt acaagcaata acagcaacaa caactggagg
    45181 aataggagaa tttgcaaata tattaattgg tggttcttat gtaatgatac tttgttattc
    45241 atataagaga agtggagatt taaaaggtgt actgattggt tttgtattag gaacaatatc
    45301 tatgactata attggttcat tagtaaatta ttttgtaatg ttgccacttt atggtcaact
    45361 tatgggacta gatgctataa taggtttagg ttcagctata aatcctcaag ttcatgattt
    45421 attcactttt gtaatttgga tgatagctcc atttaatgtg ctgaaggctg ttataatatc
    45481 tttagtaaca ttgccacttt ataaaaaaat gggaaatata ataaagaaat aattagacaa
    45541 gaaaatataa aattaaatgt attgaatagc cataatttat ttataacttc agtcctatat
    45601 tgtgattgat atattaaata tattatggct ttattaattt atcaaaaaat gtatataaaa
    45661 taagaaatat ttagacaaat ttaaatttta aaataaagga agaattaaaa cgattaacta
    45721 ttaaaatatg aaaaaggtat ctacaatata cagagcgaat ttataataaa caaaaaataa
    45781 agttattatt aaaaaactat aaagattaat aatcaaactt ttaataataa ctaatttaat
    45841 aatgataggg gtgtatattc atgcatttat ctaaaaaaat aaaaaaatta tttttagatg
    45901 ataaagggta ttattttaat agtaattgga aagatattca tattggtatt tatgatacaa
    45961 aattaggaga ttctttaaag tatatcacta atgaatatat tgaaaatatg gaaagggtaa
    46021 aatacgatta tcgtgaatta aaaaatatag aaaatcaaac tgatggtatg tgtattttag
    46081 caataaggca gaattacaag gcattagagt atgtaaaaaa tcaaaccgaa gaattatgtt
    46141 tagaagcaat aaagtataat tataaagcac ttgaatatgt aaaagaacaa acagaatact
    46201 tgtgtcttga agctataaaa aaagattgta atgcacttaa gtatgtacga aataaaacag
    46261 aagggcttat tataaaagca ataagtcatt cttccaatat agatgttgta agtatactaa
    46321 aggctttaga gactcaaaca agaaggatat gtttagaagc aattaaaaaa gatggcaggt
    46381 gtcttgcata cgttagagaa cagagtgaag aattatgtat agaggccatt aagcaaaatt
    46441 ataaagcatt aaaatatgta aaaaatcaaa cggaaaaaat gtgtatagaa tccgtaagac
    46501 aaaatggtat ggcattacaa tatgtaaata aacaaactga taaaatatgt atagaagctg
    46561 tcaaacaaga tggaagaagt atacaatttg tcaacaataa gacagaagaa atatgtataa
    46621 atgctataag atatttaaat aaaaaatata atattaaaga tgtactaagt tacatagata
    46681 agtatacaga agatatatgt atagagattg taagacaaaa tggaaaaatg cttatgtata
    46741 taaaaaatca aacagaaaaa atgtgtattg aagcagtaaa agagaactat aagtctctta
    46801 agtatgtaaa agagcaatct gagagaatat gtaaagaagc attgaagcaa aaccataaag
    46861 caaaagagta tgtaaaaatt gctattgatg attgtatata aggtgtagat acagccatca
    46921 atagtgaaag ataaaaaaag ataaagacaa gtactttata ataatctagg cttatactat
    46981 aattaattaa gcagtgatat aaattcacat gacgattata tcaaaatgga gatgaattga
    47041 tggcaaaaat atatttagaa aatgaaaata aaactagaga aataggatat aaattaggta
    47101 aacttttaaa agaaggcagt gttatctgtt tagtaggaga tttaggagct ggtaaaacta
    47161 caatgacaca aagtttggca gattcattag ggatagaaga ttatataaca agtcctactt
    47221 ttactataat aaatgaatat gaaggaaaaa tacctttgta tcattttgat gtttatagaa
    47281 taggtagtag tgatgaaatg tatgatattg gttatgatga atatgtaaat tcaaatggaa
    47341 tctgtataat agaatgggct aatctaatag aagatatact tccaaaagaa tatttgaata
    47401 tagaattgag atataaagat gaaggaagag aaatgatatt aactccaaaa ggagagtttt
    47461 ataaagagat agttgaggag ttgattaaat aatgaaaata ctaggtatgg atacgtcttc
    47521 tatggcagca agtgtagcag ttgttgaaga tgataactta atatgtgagt ttacagtaaa
    47581 caacaaaaaa actcattcac aaaagcttat gccaatgata gaaaatatgt tgagtatgag
    47641 tgatttaagt ataaaagata tggatttatt agctgtatgt ataggtccag gttcgtttac
    47701 aggacttaga ataggtatgg ctacagtaaa agctatggcc catgtaaata atataccaat
    47761 aatagcagta aattctttgg aatctctagc aaataacata aatttctgtg atagaaagat
    47821 atgttgtata ttagatgcgc agaaaaatca agtttattca gctaaataca agtttgaaaa
    47881 tggagagatg atagaattag atggtgttga tgttgtagag tttgatgctt tagtagatga
    47941 aattgtatca actaatgaag aatttataat agttggagaa gctgtataca aatataaaga
    48001 caagttagag aatataaaaa atataaaaat accttcacca gctaataatg tatctaacgc
    48061 aggaagctta tgctctttag cattaaataa atataataaa aatatagatg tacatacttg
    48121 ttatacgata aatcctatgt atatcagaaa atctcaagct gaagtacaat atgatgaaaa
    48181 aatgaagagg ctaaataatg gaagataata caaaactaat agtagatgat ataaaaatag
    48241 aagaaatgac tacagaagat atagatgaag tttttgaagt agaaaaaaat tgttttgaag
    48301 attattggtc aaaagagtct tttagaaaag agttgtctaa tgaagtagca aggtatatag
    48361 tagctaagtt aaatggaaaa attgtcggat atgtgggaat ttggcttata cttgatgaag
    48421 ggcatataaa taatgtggct gttcatagtg actatagagg gaaaaaaata ggggacaagt
    48481 tgataaaagg catagttgat ttatgtaaag ataataatat tgcatctatg acattagaag
    48541 ttagagcatc aaataaaata gcacaaaatt tatatagaaa atatggattt aaaatgggtg
    48601 gaataagaaa agaatactac agtgataata aagaagatgc aattataatg tggaaccaat
    48661 taaaagaggt gtagagttta tgagtgatat aataacatta gctatagaga gtagttgtga
    48721 cgaaacagct gcatcagttt taaaaaatgg tagagaaata ctttcaaaca taatctctac
    48781 tcaaatcgag acacataaaa aatttggtgg tgtagttcca gaagtggcct caagaaaaca
    48841 tgtggaaaat attgatatag ttgttcaaga agctttagac aaagcaaata taggttttaa
    48901 tgatatagac catatcgcag ttacatatgg acctgggcta gtaggtgctt tattggttgg
    48961 tctatcttat gctaaagcac ttgcatatac tttgaatatt ccacttgtag gagtaaatca
    49021 tatagaaggg catctaagtg caaactatat agagcataag gatttaaaac ctccttttat
    49081 aacattaata gtatctggag gtcatactca cttggttgaa gtaaaagatt atggcaagta
    49141 tgaaatttta ggaaaaacaa gagatgatgc atctggagaa gcttttgata agatttcaag
    49201 agctatgaat ttaggctatc caggaggtcc tattattgat aatctggcca agaatggaaa
    49261 taaacatgct atagaatttc caagagccta tttagaagaa gatagctatg attttagttt
    49321 tagtggatta aaatcttctg tattaaatta tctaaatgga aaaagaatga aaaatgaaga
    49381 aatagtagtt gaagatgtag cagcatcttt ccaagaggct gtagtagagg ttttatctac
    49441 taaagcacta aaagcagtaa aagacaaagg atacaatatc ataactcttt ctggtggggt
    49501 tgcttctaat tcggggctta gagctaaaat aacagagctt gctaaagaca atggtattac
    49561 tgttaagtat cctcctctaa ttttatgcac agataatgca gctatgatag ggtgtgcagg
    49621 atattataat tttataaacg ggaaaacgca tgatatgagt ttaaatgcag ttccaaattt
    49681 aaagataaat cagtagagtt agatgaattt gtaaatataa aagtattgtt tcaaaaaagt
    49741 aagtagaagt gaaattaaat ataataaaaa taaatatagt atatattaaa acttgaagta
    49801 aaactattta taatctttat attccaatga attgcaacaa attttaggat atacagattg
    49861 tctttggctt agatttgctt caagtttatt tttttctata gaaagattat ttcaaaaagt
    49921 gggtaatata cccttttttt tcattcttaa aaagttttat actaattata gaaagattaa
    49981 ggaggggaag aaatgagtca aagtaaagaa gacaaaataa gaagtatttt ggaagcaaaa
    50041 aatattaaat caaattttca aaataaagaa aatttaagtg aatttaatga aaaaaaagca
    50101 agtaaaagag cagaagactt attagatgta tattataata cattatctac tgctgatatg
    50161 gaatttccat attggtataa tagagaatat agaaaatcag atggtgatat accagtagtt
    50221 agaagagcta aagctcttaa agctgctttt tcacatatga caccaaatat aatacctggt
    50281 gagaaaatag taatgcaaaa gacacgccat tatagaggtt cttttccaat gccatgggta
    50341 agtgaaagtt tctttgttgc tcaaggagaa caaatgagag aagaggcaaa gaaattagcc
    50401 agtaacacag ctgatgaact tacaaaattt gggtctggtg gaggaaatgt tactgaaagt
    50461 tttggaaatg tcgtttcaat agctggtaaa ttcggaatga gaaaagaaga agtacctgta
    50521 cttgtaaaaa tggcaaagga atgggttgga aagtctgttg aagatttagg ttttcactat
    50581 gaaaaaatga tgccagatta tgatttaaaa gaaaacctaa tgagtacact tatatgcatg
    50641 tttgattcag ggtatacact tcctcaaggt agagaagtta taaattattt ttatccttta
    50701 aattatggat tagatggaat tatagaaatg gcaaaagaat gtaaaaaggc agttgcagga
    50761 aatgcatctg gagatgggct tattggtatg gaccgtctat atttttatga ggctgttatt
    50821 caagttattg aaggattaca aacttggatt ttaaattatg caaaacatgc aaaatattta
    50881 gaaagtatag agacagattt agaagctaaa aaagaatact cagatttagt ggagatatta
    50941 gaacatattg cacataaaca acctcgtaca tttagggaag ctcttcagtt gacttataca
    51001 attcatatag catcagtaaa tgaggatgct atatctggta tgtctatagg acgttttggt
    51061 caaattttat atccttggta tgaacaagat atagaaaaag gactaattac aaaagaagag
    51121 gttatcgaat tattagagct ttatagaata aaaatcactt gtattgactg ttttgcttca
    51181 gcgggcgtaa atggaggagt actatcaggc aatacattta atactttatc tataggtgga
    51241 ttaaaagaag atggttctac aggagctaat gaactagaag agttattatt agaagcaagt
    51301 atgagatgta gaactcctca acctagttta actatgctat atgatgaaaa gcttccagaa
    51361 gatttcttaa tgaaagctgc tgaatgtaca aagcttggtt ctggttatcc agcatgggta
    51421 aacaactcaa atggaacaac atttatgatg aaacaatttg ctgatgaagg tatgactgtt
    51481 gaagaagcaa gagcatttgc attaggtgga tgtttggaaa cgtctccagg gtgttggaaa
    51541 cagttaactt taaacggaaa aacatactct attgcaggtg gagcaggtca atctgctggc
    51601 tctggagttc actttatagc taatccaaaa attttagaac ttgttcttat gaatggtaaa
    51661 gactatcgta tgaatataca agtatttgag cctcataata agccattaga tacttatgaa
    51721 gaagtcatag aagtatttaa agattattat aaacaagcaa taaatgtttt agaaagagca
    51781 aataacattg agttagatat atggagaaaa tttgatactt ctataataaa ttcactacta
    51841 aagccagact gtttagacaa aggtcaacat ataggaaata tgggatatcg ttataatgca
    51901 acattaaacg tagaaacttg tggtactgtt actatggtca attcatttgc agcacttaag
    51961 aaacttgtat atgatgacaa agcatttaca atagaggaaa ttaaggatgc catattaaat
    52021 aattttggat ttaaagatgc attagaagta ggaaattatt ctatggcaga ccaagtaaaa
    52081 gtagataaga ctggtaaata tgatgctatt tataaggcct gtcttgatgc acctaaatat
    52141 ggaaataatg atttgtatgc agataatatt cttaaaaact atgaggtatg gttatcaaaa
    52201 gtatgtgaag aagcacaatc tttatatgct aagaagatgt acccttgcca aatatctgtt
    52261 tctacacatg ggccacaggg agctgctacc ttggctactc cagatggtag actaagtgga
    52321 acaacatatt cagatggttc agtctctgct tatgcaggaa cagataaaaa tggagtatat
    52381 gcattatttg aatctgcaac tatttgggac caagcagtag ttcaaaattc tcagatgaat
    52441 ttaaaacttc atccaactac tataaaagga caacaaggaa ctaaaaaatt attagattta
    52501 acaagaagtt atttaagaaa aggtgggttc catattcaat ataatgttgt agattcagaa
    52561 acgttaaaag atgcacaaaa aaatcctgat aattatcgtc aattaatggt acgtgttgct
    52621 gggtttactc aatattggtg tgaattaggt aaaccaatac aagatgaagt aattgctaga
    52681 acagagtatg aaggggtgta aaatatgaga aagcatagtg attgtatgaa tttttgtgca
    52741 gtagatgcaa ccaaaggaat ttgtagatta tcaaaacaaa tgattaattt agatgatgca
    52801 gcatgtccag agataaaagt aatgccaaaa tgtaaaaatt gtaaaaattt tgttgaagct
    52861 aatgatgaag gtataggcaa atgtgttggc ctagagaaag aagactgggt atattcaaca
    52921 ttgaatgcaa ttacttgtga aggacatgtg tttaatgagt agtcaaaagc aattagaagg
    52981 catgattttt gatgtacaaa gcttttcagt tcatgatggt ccaggttgta gaacaactgt
    53041 atttttaaat ggatgtccac tgagttgtaa atggtgtgca aatccagaaa gttggactgt
    53101 aagaccacat atgatgttta gtgaattatc ttgtcaatat gaaaatggat gtactgtatg
    53161 tcatggtaag tgtaaaaatg gtgcattgag ctttaatctt gataataagc cagttataga
    53221 ttggaacatc tgtaaggact gtgaaagttt tgaatgtgtc aactcatgtt attataatgc
    53281 gtttaaatta tgtgcaaaac cttacactgt agatgaactt gtgcaggtaa ttaaacgtga
    53341 ttctaacaat tggagaagta atggaggagt aacatttagt ggaggtgagc cactacttca
    53401 gcatgaattt ttacatgaag tattattaaa gtgtcatgag gtaaatatac acactgccat
    53461 tgaaacgagt gcatgtgtat caaatgaagt ttttaataaa atatttaacg atattgattt
    53521 tgcatttatt gatataaagc atatggatag agaaaaacac aaagaacaaa caggtgtgta
    53581 taatgattta atattagaaa atatatcaaa ccttgcaaat tctgattgga atggaagatt
    53641 agtacttaga gtaccagtta tctctgggtt taatgatagt gatgaaaata taagtgatat
    53701 tatatctttt atgcacaaaa ataatttggt agaaattaat ctattaccat ttcacagatt
    53761 aggagaatca aaatggattc aattaggcaa ggaatatgag tattctgata agggtgatgt
    53821 tgatgaaggt catctagaag aattacaaga tatatttttg gataatggta tagcttgtta
    53881 tgttggccat gagacagctt tctaaaatta aatacaagtt ttaattaaaa aaaggatgtt
    53941 acactaaaag ctagagttac atcctttttt atgtggtttt tatgtagaaa taattaagta
    54001 aagttttata tgttttatat attgtttata ttgctttatg tccataaata ttgctttaaa
    54061 tatactttat atatttttta tagtttaaat tacagttaga gaatatatta cgtttacttt
    54121 attgaagcag aagttttgtg gtaaaatact actatgaaaa aatttaatag aatatatttt
    54181 agaaacaact aaaaataata gttaggagga agacatctat atgaacaaat catggagcaa
    54241 cttgattatt aagaataaag acagaaaagt acgttcaggg tggattatta tagctgttat
    54301 ggctaccttt tacatacttc agtattattt aagcatgaca cttgtggaaa taataagaaa
    54361 aattctgatt gcgacaggtg atattaattt aaaaacaaac tatttttcag aatatgctaa
    54421 ttgggtaagt gatgttgggt tacaggttgt atttcaaatt ctaacagagt cacttacgat
    54481 tattattcct ataattgtat ggagatttat tatgaaaaat cctattcgtg aaatgggatt
    54541 acattcttat agaattaaga aaaaagaagg atatgtagga atgttattag gaatatttaa
    54601 ttgtacagta atctttatta taacaataac aattggtggt ggtcatgtta cttcatgggt
    54661 accaaaaatt tcacctttaa cagtttattg gatacttttc tttgctttag ttgcttttgc
    54721 agaagaaatt ttaaatcgtg gtttttttat ggcagtttta cgaagatgta aaaatattta
    54781 ttttataatg attgttccat ctgttatttt tgggttggtt catatatgga atcctgatgt
    54841 tactctttta tctgtaatta atattataac tattgggatt cttttttcat atatgtttat
    54901 aaaatcgtcg aatatatgga tgtgtatagg ttatcatttt acatggaatg tatttcaggg
    54961 gattatatat ggtatgccta taagtggact tcaagttcca gagattataa ctacacaaat
    55021 cactcatggt aatctattaa atggagggat gtttggtatt gaaggtggaa ttttgactac
    55081 ttttgttaat ctacttagct ttatatttgt atggtattac tatagagatt ctaagtatga
    55141 ttttgttagt gataaagtaa atgtgaccaa tatcaagaat tagttgatta taataaattt
    55201 taataatatc ttctaagctt aaagtattct gtaggattgt tggaaattta caaaaatata
    55261 aaaataactt ggatattcta tttactccaa gttattttta tattcttttg taaatagaaa
    55321 tggaacataa aaaattaaaa caaccataga tactattagt atatcatggt aagtgatagt
    55381 tgattcttta gaatttgtga taagaaaagc actattattt aaaacatgaa ttatagcaca
    55441 aaaccagata ttcttagttt ttatataaag atatcctaaa aatattgaaa ttccaactat
    55501 atgtattgaa cgtaatatta ttcctaatat tggcgcttca ggtgtatata atgtaaatat
    55561 tagtggtaag tgccacaagc tccaacacat acctaatatt ataactccta actttttacc
    55621 aaatttatca aaaaaaatat tctgtaaaaa acctctccag gcatattctt cactaaaaaa
    55681 aatataaata gtagttaatg atgttattgg agtaaatata aattttatga taccactata
    55741 attaggttga gccccttgta gtattagtat aaatgatgtt ggaacaatta cagaaatcat
    55801 aaagtaaata attaataaag aacctagttt aatatttttt acaggatata aatttttttt
    55861 atttgatgaa tatattataa ttgataagct acttataaaa gttaatatta ggtttataat
    55921 tataaattca ttattattta ttagatttaa taacttaaga acaattaata atgaataaat
    55981 aagaaaaaat aatatgatta gtgaataaaa ttcatacata tcattattta atccttcagt
    56041 ataaaacttt gcaatagcaa ctgaagatag aggtaatatc atcatgaatg atgcaaagtt
    56101 ttctggatca ataaatttat tataatataa cagtaaacct aatgaataag ttaaaccaaa
    56161 gtttataaag aaaaagataa taatttgtat tttttttctt tttatttcat ttttaataaa
    56221 tactgggttt agaatattta tccatattaa ttttaagttc attaatttaa tactccttta
    56281 caatatagat tcttaactaa attaaaatat ttta
//
LOCUS       DAEQAF010000014        51939 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.014, whole genome shotgun sequence.
ACCESSION   DAEQAF010000014 DAEQAF010000000
VERSION     DAEQAF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 51939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51939
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.014"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            427..3069
                     /gene="adhE"
                     /locus_tag="KRN00_000985"
                     /gene_synonym="adhC"
     CDS             427..3069
                     /gene="adhE"
                     /locus_tag="KRN00_000985"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH1826853.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            complement(3432..3773)
                     /locus_tag="KRN00_000986"
     CDS             complement(3432..3773)
                     /locus_tag="KRN00_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826854.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(3800..4471)
                     /locus_tag="KRN00_000987"
     CDS             complement(3800..4471)
                     /locus_tag="KRN00_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826855.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            complement(4483..7059)
                     /locus_tag="KRN00_000988"
     CDS             complement(4483..7059)
                     /locus_tag="KRN00_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1826856.1"
                     /translation="MKDNLKIVLRYIKSYKARSLAIVVSIILATSLVVGIGTLSRSAQ
                     QADVDRLKRELGADHVYFKNIKKNQLKSIKSSKDIKNLGITSYYASTDVNEKLPINIL
                     YTNKNYLTSHSKLIKGRFPKASNEVVVEKWILNSMGLKPEINQNLTFKLYQKENPETF
                     KVVGILEDRFIEKKKGQCEIFSNLNESELNDFTTYIEFNEGSDINTNIDNIIKNAMLD
                     EKSIGRNSMLIESTMKNGTLDNSSKYVAIAMSLFAGIVIYSIYVISIYQRVQEYGVLR
                     AIGSTNFRIFKLMLYELFILALIAMPIGICIGMGGAQIFNRSVGNIQFEGNINVTPFV
                     IPDKIILLSIACTILIILIISFFTYLKIRRISPIDAIRKTFGADKNVTKVNYLISKLT
                     LNMSVTKSISAKNIFRNKKGFIIIVLSMSIGGIIVIKDNYKYSFLDVQNKSTQEQTYM
                     NADFILSNVYLNEIGNNTSFKDIKGFNDNQIDKIKNIDGIDKVKTASILNTRIEVNKI
                     NRLDYYEAINSTPYYKLNPLFIKNKTTGKYTLKQKLKGYNDEMIKSLEKYLVSGNINL
                     KKMKKENLAIVYVPEISKTQKYTKTFTPGEGTPAVDIKVGDTIKVKYPKGGMDTGLYE
                     SLKDNYEYLEYEFKVGAIISYPFADNGMYSGDDGIDVITSSEYLKKLTGVDKYNLVYA
                     DLNENANKKKINNLLGKIGSEVPGTTTVDMMVEKENSDKMTSRTMIYSYGIVAIMFII
                     SVLNIINNISYNLTSRTSEFGMLRAIGISERGFKNMILYEGILYGVLSSIITIVSGII
                     IQFKMYYMQGFVSYGLGFSIDYKIYILVVVANIIVGILATYIPSRKINKISIVEAINI
                     TE"
     gene            7267..8202
                     /locus_tag="KRN00_000989"
     CDS             7267..8202
                     /locus_tag="KRN00_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1826857.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            8221..8958
                     /locus_tag="KRN00_000990"
     CDS             8221..8958
                     /locus_tag="KRN00_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826858.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(9143..14200)
                     /locus_tag="KRN00_000991"
     CDS             complement(9143..14200)
                     /locus_tag="KRN00_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBH1826859.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSHLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIEGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(14225..14644)
                     /locus_tag="KRN00_000992"
     CDS             complement(14225..14644)
                     /locus_tag="KRN00_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826860.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVPDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            complement(14877..15128)
                     /locus_tag="KRN00_000993"
     CDS             complement(14877..15128)
                     /locus_tag="KRN00_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826861.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            15217..15948
                     /locus_tag="KRN00_000994"
     CDS             15217..15948
                     /locus_tag="KRN00_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBH1826862.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            16007..16918
                     /locus_tag="KRN00_000995"
     CDS             16007..16918
                     /locus_tag="KRN00_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1826863.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQITSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            16969..17781
                     /locus_tag="KRN00_000996"
     CDS             16969..17781
                     /locus_tag="KRN00_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBH1826864.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            17889..18581
                     /locus_tag="KRN00_000997"
     CDS             17889..18581
                     /locus_tag="KRN00_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1826865.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            18668..19609
                     /locus_tag="KRN00_000998"
     CDS             18668..19609
                     /locus_tag="KRN00_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826866.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            19646..20803
                     /locus_tag="KRN00_000999"
     CDS             19646..20803
                     /locus_tag="KRN00_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1826867.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            20955..21515
                     /locus_tag="KRN00_001000"
     CDS             20955..21515
                     /locus_tag="KRN00_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1826868.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            21543..22034
                     /locus_tag="KRN00_001001"
     CDS             21543..22034
                     /locus_tag="KRN00_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826869.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            22263..22814
                     /locus_tag="KRN00_001002"
     CDS             22263..22814
                     /locus_tag="KRN00_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1826870.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            22900..23832
                     /locus_tag="KRN00_001003"
     CDS             22900..23832
                     /locus_tag="KRN00_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBH1826871.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLSIW"
     gene            23887..24750
                     /locus_tag="KRN00_001004"
     CDS             23887..24750
                     /locus_tag="KRN00_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1826872.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGSINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            24997..26859
                     /locus_tag="KRN00_001005"
     CDS             24997..26859
                     /locus_tag="KRN00_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1826873.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGTRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPLMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            26862..28328
                     /locus_tag="KRN00_001006"
     CDS             26862..28328
                     /locus_tag="KRN00_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBH1826874.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            28352..29188
                     /locus_tag="KRN00_001007"
     CDS             28352..29188
                     /locus_tag="KRN00_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1826875.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFIFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            29569..29706
                     /locus_tag="KRN00_001008"
     CDS             29569..29706
                     /locus_tag="KRN00_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826876.1"
                     /translation="MKNKKFNVITLIILDNHIYAINKEQISTNSKRIYFEKSGFFSDY
                     K"
     gene            29771..31354
                     /gene="asnB"
                     /locus_tag="KRN00_001009"
     CDS             29771..31354
                     /gene="asnB"
                     /locus_tag="KRN00_001009"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1826877.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(31433..32029)
                     /locus_tag="KRN00_001010"
     CDS             complement(31433..32029)
                     /locus_tag="KRN00_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBH1826878.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSIIKIRINTNG
                     LSDLIHNKKTAILLKDVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFAKDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(32056..32583)
                     /locus_tag="KRN00_001011"
     CDS             complement(32056..32583)
                     /locus_tag="KRN00_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBH1826879.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            complement(32945..33943)
                     /locus_tag="KRN00_001012"
     CDS             complement(32945..33943)
                     /locus_tag="KRN00_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBH1826880.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            34620..35819
                     /gene="hadA"
                     /locus_tag="KRN00_001013"
     CDS             34620..35819
                     /gene="hadA"
                     /locus_tag="KRN00_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBH1826881.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            35858..36658
                     /gene="hadI"
                     /locus_tag="KRN00_001014"
     CDS             35858..36658
                     /gene="hadI"
                     /locus_tag="KRN00_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBH1826882.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            36673..37899
                     /gene="hadB"
                     /locus_tag="KRN00_001015"
     CDS             36673..37899
                     /gene="hadB"
                     /locus_tag="KRN00_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBH1826883.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            37899..39026
                     /gene="hadC"
                     /locus_tag="KRN00_001016"
     CDS             37899..39026
                     /gene="hadC"
                     /locus_tag="KRN00_001016"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBH1826884.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            39074..40207
                     /locus_tag="KRN00_001017"
     CDS             39074..40207
                     /locus_tag="KRN00_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH1826885.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            40240..41025
                     /locus_tag="KRN00_001018"
     CDS             40240..41025
                     /locus_tag="KRN00_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1826886.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            41044..42081
                     /locus_tag="KRN00_001019"
     CDS             41044..42081
                     /locus_tag="KRN00_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1826887.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            42564..44195
                     /locus_tag="KRN00_001020"
     CDS             42564..44195
                     /locus_tag="KRN00_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1826888.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(44330..45256)
                     /gene="fba"
                     /locus_tag="KRN00_001021"
     CDS             complement(44330..45256)
                     /gene="fba"
                     /locus_tag="KRN00_001021"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBH1826889.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSVNSIN"
     gene            45586..45915
                     /locus_tag="KRN00_001022"
     CDS             45586..45915
                     /locus_tag="KRN00_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBH1826890.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            45915..46637
                     /locus_tag="KRN00_001023"
     CDS             45915..46637
                     /locus_tag="KRN00_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH1826891.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNPGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            46664..48025
                     /gene="rlmD"
                     /locus_tag="KRN00_001024"
     CDS             46664..48025
                     /gene="rlmD"
                     /locus_tag="KRN00_001024"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH1826892.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVRA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            48536..49570
                     /locus_tag="KRN00_001025"
     CDS             48536..49570
                     /locus_tag="KRN00_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBH1826893.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEVLKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            49657..49860
                     /locus_tag="KRN00_001026"
     CDS             49657..49860
                     /locus_tag="KRN00_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBH1826894.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            50031..51191
                     /locus_tag="KRN00_001027"
     CDS             50031..51191
                     /locus_tag="KRN00_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBH1826895.1"
                     /translation="MKLNKTLLAIGMSVSLLIASCPTSNALNSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGSVSAVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSISDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            51450..51590
                     /locus_tag="KRN00_001028"
     CDS             51450..51590
                     /locus_tag="KRN00_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826896.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
BASE COUNT        19694 a         6181 c         8761 g        17303 t
ORIGIN      
        1 tataaaaaga aaaattgcat acaagtcaaa aataagtgtt attttataaa aatacgacaa
       61 aaattttatt tactacttat acaaataaca tgcaaataac atataaaatt taataagtaa
      121 aaaaaatgaa agatataaat tatcatttta gtattttatt tagtcgaagt aaattattca
      181 aatgaaatat atctcattta gataaaaaat tttagtaaaa gtaaaaaaaa taatatattt
      241 gttaaaaaat aaattgacaa aatattcaga aaaaaatttc ttgacctaag agagtaaaat
      301 aaataaaatc taaggtatag agatgaaatc tataaaatta ttttaagtat aagttaaaaa
      361 tatagatgat gcatttaaga tttataaaaa ttagagatgc ataattattt tagggaggtt
      421 tttagtatgg agaaaaaaga aaaggtagta gaaaaatcaa atgttgaagt atgtagtcct
      481 gaaattgtca acagtgttga aacattaaga atgagattag aagaaattag attggcacaa
      541 aaagaatttg caacatttac gcaagaacag gtagataaga ttttcttagc tgcttcaact
      601 gcagctaatc aacaaagaat acctctagca aaaatggcag tggaagagac tggtatgggt
      661 attgttgaag ataaggttat aaaaaaccat tttgcctcag aatatatcta taatgcttat
      721 aaagatacta aaacttgtgg tgtcatagaa aaagatgaag catttggttt tacaagaatt
      781 gctgagccag taggtgtttt atcagcagtt ataccaacaa ctaatcctac atcaactgca
      841 atattcaaat ccctaatagc actaaaaact agaaatggta taattttctc tcctcatcca
      901 agagctaaaa actgtactat agaagcagct agagttgtac atgatgcagc agttaaggca
      961 ggagcaccaa aaggacttat aggttgggta gatgttcctt cgattgaatt aactaatgtt
     1021 gtcatggcag aggcagacct tatattagct actggtggac ctggaatggt taaatctgca
     1081 tactcttcag gtaaaccagc tgtcggagtt gggcctggaa atgtacctgc aataatagat
     1141 gagagtgcag atataaaaat ggctgtaagt tcaatcttag tatcaaaatc attcgataat
     1201 ggtatgatat gtgcttccga gcaagctgta atagtaccag aaaaaatata tgaagaagtt
     1261 aaaaaagaat ttaaatatcg tggagcacat ttcctaaata aagaagaaac tgaaaaagta
     1321 ggaaaagtag taataattga tggttcatta aatgccagaa tagttggaca accagcacat
     1381 gtaatagcca aaatggcgga tgtagaagtt ccaaaaacag ctagaataat aattggtgaa
     1441 gtagaatctg ttgaattaaa tgaacctttt gcacatgaaa aactttctcc tgtacttgca
     1501 atgtacaagt ctaaaagttt tgaagatgca gttgctaaag cagaaaaatt agttgcagat
     1561 ggaggctatg gtcatacatc ttcattatat gcagactcta taaatcatcc agagagagta
     1621 gaaaagtttg taaatgctat gaagacttgt agagtattag ttaatactcc atcatcacaa
     1681 ggtggtatag gtgatttata taactttaaa ttggcaccgt ctcttactct tggttgtggt
     1741 tcttggggtg gaaactcagt atctgaaaac gttggagtaa aacatttgct taatatcaag
     1801 acagtagctg aaaggagaga gaatatgctt tggttcagag caccagaaaa ggtttatttc
     1861 aaaaaaggat gtttaggtgt agcagcaaga gaatttaagg atgttatgga taaaaagaaa
     1921 gcatttatag taacagattc tttcctatat aataatggat atactaagaa attaactgat
     1981 ttattagatg agatgggaat taagcatact acattctttg atgtagctcc agacccaaca
     2041 ttagcttgtg caagagaagg agctaaagct atggctgatt tccaaccaga tttaataata
     2101 gctgtaggtg gaggaagtgc aatggatgct ggtaagataa tgtgggtaat gtatgagcat
     2161 ccagaagtag atttccaaga cttagctatg agatttatgg atataagaaa aagagtatat
     2221 gtatttccta agatgggtga aaaagcgtat tttgctgcta tcccaacttc agcaggaact
     2281 ggttcagaag taactccatt tgcagttata actgaccaag attcaggtgt aaagtaccca
     2341 ttagcagatt atgaattaat gccaaacatg gctataattg atgctgatat gatgatggag
     2401 atgccaccaa gattaacagc agcatcaggt gttgatgctt taacacatgc attagaagca
     2461 tatgtatcta tgttaagaac tgaaccagct gacggtctag cactacaagc aggtaaaata
     2521 atatttgaat atttacctcg tgcatataaa aatggaaaga atgataaaga agcaagagaa
     2581 aaaatggcaa tggcatctac tatggcagga atgtcttttg caaatgcctt cttaggaata
     2641 tgtcactctt tagcacataa attaggtgca ttccaccatg ttcaacacgg tgttgcaaat
     2701 gcattattaa taaatgaagt aatcaagttc aattgtgcag aagctccaaa taagatgggt
     2761 gcattctcac aatacagata tcctgattgc atacaaagat atgctgaatt tgcttctttt
     2821 gcaggtatta aaggaagtac agaccaagaa aaagtagata atcttataaa agcaatagat
     2881 gaactaaagg caaaagtagg tcttcctaag actataaaag aggctggagt agaagaatct
     2941 aaattcttag aaagattgga tgctatggtt gaacaagctt ttgatgacca atgtacaggt
     3001 gctaatccta gatacccatt gatgagtgaa ttaaaagaga tatatctaaa agtttattat
     3061 ggtaaataat atctattgtg caacataggt tctattgggt ttgtatataa attattagat
     3121 ttgaatataa atagagtttt attagagaca cgtagaagta actataaata atagattata
     3181 acttaaattc taaatggaaa tgataaaaag tcagtaattt tttaatggta atttcgaata
     3241 tgtgtattta atcaattaac tttaaaatta gtcggaaaat ttttttatta catataattt
     3301 taaagcataa tatataaaaa actttatgaa aaaattataa aaatattcag aaaattctat
     3361 tgactaattt atttatcatg atataataag tttagaaaag aaaaaaattg gggcctatta
     3421 aggccccctt actatttttt gatagattta tttaaaatta ctttctcatt ttgatttttt
     3481 atatttatta tagagtcagt ataatccact tcaaagttgg caaaagcaga gaataaatct
     3541 atatctctta acaaatgaat tgtcatacat tgattgttct tatttagcct tagaatcaat
     3601 gctcttacaa atggaaattg tattctagaa ttaaataagt tagaaccatc agtatctata
     3661 tctaagctac gataattaat atctataaat atatctacat cgtcattttc ttctcttatt
     3721 attctgtagt caaaatccaa gtttaaattt aaattaccta aaatcaataa catttaaatc
     3781 ctcttttcta taaatagttt tagagtgtta atttaagctc tccatctatt atagatataa
     3841 ttctatctgc ttttctagca atattttcat tatgtgttat tattataagt gtttggttat
     3901 atttttttat agaacttttt agtaaatcca tgacttcttc tgtagtttta ctgtccaaat
     3961 ttcctgttgg ttcatctgct aggattatac ttggttttgc agataaagca cgtgcaatag
     4021 caactctttg ctgttgacca ccagataatt ggttgggaag atgatttttc ctttcattaa
     4081 gacccaataa atttataagg tcatcaatat attctttatc tattttttta ttgtctaact
     4141 ttagtggtaa ttctatattt tcctttacat ttaatacagg aattaagtta tactgttgaa
     4201 agacaaatcc taccttttgt cttctatatc ttgctaattc tttatctgaa agacaacata
     4261 tatctttacc atctaccttt atagtaccat tacttggtct ttcaagacca cctactaaat
     4321 gtagaaatgt acttttccca cttccacttg gtccaattat agcaacaaat tcgcctttat
     4381 ttatttttaa atttgcattc tttagtgcat gtacagatgt ttcctttttt ccataaatct
     4441 tacctaagtt aatagtttcc aatataggca taattattcc tcctattctg taatgtttat
     4501 agcttcaact atactaattt tatttatctt tcttgatgga atatatgtag ctagaatacc
     4561 tacaattata tttgctacaa caactagtat atatattttg taatctattg aaaatcccaa
     4621 tccatatgat acaaagccct gcatataata cattttaaat tgtattataa ttcctgacac
     4681 gatagtaatt atacttgaga gtacaccata taatattcct tcataaagta tcatattttt
     4741 aaagcctctc tcagagatac caatagctct taacattcca aattcactag ttcttgaagt
     4801 taagttataa cttatgttgt ttattatgtt aagtacactg attatgaaca ttattgctac
     4861 tataccataa ctataaatca tagttctaga tgtcatctta tcagaatttt ctttttctac
     4921 catcatatct actgttgtag ttccaggaac ttcacttcca attttaccta aaaggttatt
     4981 tatttttttc ttgtttgcat tttcattaag gtctgcataa actaagttat acttatctac
     5041 accagttaat ttttttaggt attcgctact cgttattaca tctataccat catctccaga
     5101 gtacatacca ttatctgcaa aaggataact tataatagct ccaactttaa attcatattc
     5161 taagtattca taattatctt ttagactttc ataaagccct gtatccatcc caccctttgg
     5221 atatttgact tttatagtat cacctacttt tatatctaca gctggtgttc cttcaccagg
     5281 agtaaaagtc tttgtgtatt tctgtgtttt agaaatttct ggtacatata caatagctaa
     5341 attttctttt ttcatttttt tcaagtttat atttccactt actaagtatt tttctaatga
     5401 ctttatcatc tcatcattat aaccttttag cttttgcttt agtgtatatt tgccagtagt
     5461 cttatttttt atgaacagag gatttagctt ataataagga gttgaattta tagcttcgta
     5521 gtaatctaat ctatttattt tatttacctc tattcttgtg tttaagatac tagcagtttt
     5581 gactttgtca attccatcta tattttttat tttatctatc tgattatcat taaacccttt
     5641 tatatcttta aaagaagtat tgttaccaat ttcattgaga taaacatttg atagaataaa
     5701 atctgcattc atatatgttt gttcttgagt agatttgttt tgcacatcta aaaaagaata
     5761 tttataattg tcttttatga cgattatacc tcctatactc atagataata caattataat
     5821 gaaccccttt ttatttctaa agatgttttt cgcagatata gattttgtta ctgacatatt
     5881 taaagttaat tttgatatta aataattaac tttggttaca tttttatcag ctccaaaagt
     5941 ttttctgata gcatcaatag gagaaattct tcttattttt aagtatgtaa agaaacttat
     6001 aattagtatt attagtattg tacatgcaat tgataagaga attattttat ctggaataac
     6061 aaaaggtgta acatttatat ttccttcaaa ttgaatattt cctacagacc tattaaatat
     6121 ttgtgcacct cccataccta tacatatacc tataggcatt gctattagag caagtatgaa
     6181 aagttcataa agcataagtt tgaaaatcct aaagttggtg gaaccaatag ctcttaagac
     6241 gccatattcc tgtactcttt ggtatattga tataacatag atactatata ttacaatacc
     6301 agcaaataga ctcatagcaa ttgcaacgta tttacttgaa ttatctaaag taccgttttt
     6361 catagtagat tctataagca ttgagtttct tcctatactt ttctcatcta acatagcatt
     6421 ttttattata ttgtctatgt ttgtatttat atcactgcct tcattaaatt caatataagt
     6481 tgtaaaatca ttcagttctg attcattgag attagaaaaa atttcacatt gtcccttttt
     6541 tttctctata aatctatctt caaggattcc aacaacttta aaagtttctg gattttcttt
     6601 ttgatataat ttaaaagtaa ggttttgatt tatctctggt tttaagccca tactatttaa
     6661 aatccatttc tcgactacca cctcattgct agcttttgga aatcgacctt ttataagttt
     6721 agaatgacta gtcaaataat ttttatttgt atatagtatg tttataggta atttttcatt
     6781 aacatctgta gacgcatagt aagatgttat acccagattt ttaatatctt tgctagattt
     6841 tatggacttt aattgatttt tctttatatt tttaaagtat acatggtcag ctccaagctc
     6901 tcttttcaat ctatctacat ctgcttgctg agcacttctt gagagagtac caataccaac
     6961 aacgagtgat gtagcaagaa ttatactcac aacaattgct aaagacctag ctttataact
     7021 ttttatatac cttagtacta ttttcaaatt atctttcata tttaccactt cctttcttaa
     7081 ctaaatcaat tatatattta tctaaaatat atagcaaagt aagtattttc aaattttaag
     7141 tagttaattg tacaaattca tctgtatttt tacaagttta attaatatat atgtaaattt
     7201 taacttttta cataattttt ttaaaatgat ataatcccta tataaattgt agaggggagg
     7261 ggaatcatgg ataacaattt tgtatttcct atagtaatac taactttgtt tatatttagc
     7321 aatcttataa tgaataagta taaattttac aaagaattag acatattaaa aagaggcata
     7381 ttaacatttt ttatatcgtg ttttgcattg attttattta tggagggcac taaatatata
     7441 caattaaggt taggatatag ttttttactt gaaggagtat taaatattat actttttttg
     7501 gttttaatta ttttaagttt ttatacaggc tttaaagtta taagattgat aaataataat
     7561 aatgaacagg aatataaact acaaaaacta gatagtaaaa taaatcataa ggataatata
     7621 attatcaaat taagaagtca aaaacatgac tatttgaaac atttgcaagt agtgtattct
     7681 ctattaaata ctgggctaga tgaagatgcc aaagaatata taatgaatat atcaaatagc
     7741 tttaaatcaa aaaattcaag gtatggaaaa gtatcttatt tagatgctat agcttcatta
     7801 aaatacgagg aatgtcttga aaaggatata tcttttgatg tctacattca agattttatg
     7861 gataatttag agattgaacc taatgatatg agttcagtac tattaaacat aatagataat
     7921 gcaatagagt ctttgtctac tataaaaaaa gaaaagaagt atataagatt acatgcatat
     7981 gaagatgaat ttcagtatat tatagctata aaaaataatg gtcctaaaat acataatgtt
     8041 gaaagtatat tttggaatgg atttagtact aaagaaggac aagatagggg atatgggcta
     8101 catttagtta aaaatatatt agataagtat gattatagta tacttgtaaa tagtgatgat
     8161 tttttaactg aatttgtaat cttaatccca aaatattatt agttaggagg agaaaagtct
     8221 atgataaaag ttttgatttg tgatgatgat aagattgtaa gagatgatat agcaaatata
     8281 gctaaagagt ctggatatgt agattatgtt aaaaaagtta aggatggtat agaggcaatt
     8341 gaatttataa aaaatgagaa aatagattta ttgattattg acattgatat gccatataaa
     8401 aatgggattg attctgctga agaaattctt tctatagata aggatataca tatagtattt
     8461 gtgacgggtt tcgctgatta tagtcttgaa agctttaaag tgcatcctat agattttgta
     8521 gttaaaccat ttaaaaaaga aaaaatactt gattcaatta acatagcaat agaccatatt
     8581 aactcccata agattgctaa taataatttt atagaagaca ccctttttgt atataaaata
     8641 aggaagcaga tacatatgat taattttgat gatatagtta tgtttgagaa aaattcaaga
     8701 gcaattaatc tacacactaa agatgaagat ataataaagt tttatgagaa ctttgatgat
     8761 ttaaaaaaac gcctacctcc taatttcttt atgacccata gacaatacat agtaaatcta
     8821 agatttatac ataaggttat acctataaat aaatcttcat tagagataag gtttataaat
     8881 tttcaagaaa atgccatatt aaacaaatct ctagaaaaag attttttata tagattttat
     8941 agggttaaaa gattctagtg aagatagaag aaaaatactt tttgtgtgat ataataagta
     9001 ccgtaaagat aatgtataag agaagtttat ataaaaatta tttgtaatta tgatttaatc
     9061 tatataaatt acagtatagg atatattgga ctttctaatt tttttaagaa agtccaatat
     9121 attttagaga tagtttttat acttataaat tacttaagat actagggtct ttaatcttac
     9181 tatcttcagc aagtaatagt atcttagaca taatctcagc agttttaggg tcttcatcag
     9241 cgaatggaag gaatatctta cctctacttt gagaatgtat aggaagtata ttcaaagcac
     9301 ccatcccttt tttatgtaca ataccagaac ccatatgcac agaatactca cctaaattac
     9361 ctgctataag agcatgagag ccttcaaaat tgacattgtt aatttttaat aataataaaa
     9421 gttctttagc aattgctata cgcatctcta cagtagaatg gctagtttca gggtcaacac
     9481 caccagcatg agcgacactt acaacaaggt ctatatcacg cataacttct gagaatagaa
     9541 ttggaggtat agaagctaat tctaaacttt tataagtttt tctatcaaaa aattctactg
     9601 tttcaatagt aggaggctct atatctgctg gtgaaaacca atctgcaagt gcaaacatct
     9661 ttgccactat attttcttta taaaatactt tctgtaatcc ctcttcataa tcgacagtcc
     9721 aaagctgatt tctaagaagt gctacagttt tctttggctg aatttggtga ccagcatatc
     9781 tgcgagatat agttttttca gataattcat cactatttat tctataatac tcacggaata
     9841 cttgcttaaa tggttgaaca atttgcttac taaataaatc atgttggaac tcactccact
     9901 taccagattc aaacaaatga actggatgtg caagttttaa tttatttttt gccgtcaact
     9961 tataagtttc accttctata ttgcaaataa agaacttaga cttatcatta taaacatatc
    10021 caatattatc atcacatacc catactagat ttttaattaa agggcagata actggatttt
    10081 tatagatatt ggcaatttct ttaactgtaa atactatttc atttttcata gcttgttcta
    10141 aactctgttt tgcacgagaa tactgactct ttaaatcttt ttggacagat ttaagttcaa
    10201 gtacatatgg atgtttagca atagcttttg gtatactctt taaagacttg ttgccttttt
    10261 gaactttagt agatgctttt ccgttttcat caacatctat ccaaattgaa gtaccatcaa
    10321 tatcttttgg tttaaataga tgagcaactt catttagttt ttcagtctca agagcccaca
    10381 tcatacgatt tacatctcca aatccagcac ttctagctag attttctagc gctatagtac
    10441 aagcttttga ttcactttca cgacgttgtg caccaaattg cttgctttct ttagcaaact
    10501 tttgaataaa ttcataacgg aaagttgctt cttttaggtc tccttttttc ataggaagta
    10561 aagagaaact tctcaattta tcttgatttc tatttgtttc aatttctttc atcaacatgt
    10621 ctttatcaag cttaccaagt gtagcatcag catagagttg tgcacgtcta tgagagttac
    10681 caccactagt tatatattta gctgacttgt aaagtatatt gaatctttct tccccaatag
    10741 ttttatatga atctaaaaac caatctacat caaatgcacc atcaatgaaa ctacgtggtg
    10801 aaatagggga gaatagagca acctctgatt ctttttgtgc agagaagcct tcatttatat
    10861 gtgcatggaa gtaccaaatt gtacttttca gacccttcca gtttaaatat ttttcaatta
    10921 tgtttaccca ttgaggggca tacatagcag attctatcaa tcttaactca gtaatgtcgg
    10981 tatttttaag taaacttttt aatttttttg aatcatcttc tttagtagga tagcaatttt
    11041 taagtagaga acttaaaaca tctttttttg aataattgct accatatgaa tatcctctct
    11101 ggaaagtttc tttaccaaga gcgaccaaaa tatttacaaa ataatttata ccttcaaagt
    11161 attgtatatt attagctaga tgagacactt ctgttggcat atcacctcta cgtgattcaa
    11221 tttctataat tcggtttgta acagttttta aattatcttt aagccaaggg tacttttcta
    11281 atgtgtcgcc agcccatcta ggatttgtca atgttcttat tatatttgat gcgttgtatc
    11341 cacttatcat ttctctatta acttgctctt cagtcattaa tcctaattca tgtgcacgag
    11401 caaacacatt tatgctagta tagaaaggaa acttatattc tagcaactga taatttgaaa
    11461 acgtagtgta gaaaaactta gtaaaagaaa tatcatcata aataaacgaa tgtgctttat
    11521 caagccaata gtttaaaata ggggcattta aagcagggca gtattcattt tgtctgtaat
    11581 agtttttagt aaattcaact ctttgttttt tacattgttc tatagtcaat aagtttctaa
    11641 gtttatagta tatttctaaa caatagttaa atatttcttt atggtcaaac tcatttagta
    11701 aaactcttaa aagttttctt gtaagtccat taaatttaag tttttcaagt tttgtatata
    11761 ttttattttg ttttttagag tcaaggacat ttgaatatat agatgaaaac caactttttt
    11821 ctgtttcatt atatccacat gtacttatac tataaaataa gatatcaagt attaatttgt
    11881 aatctaagtc aagtttttta ctagtttctc tccaaagctc tgctaatgga taattatcaa
    11941 gagtatcatt agaaacttta tatttaatag gagtcaagtt ataagtagaa taacctaaaa
    12001 gtactttgtc tacattacct gaccatcttt caacttcata ttcataatct gcattttcag
    12061 taataagctc atcaaatttt tcataaactt ttattatttt atttatatcc gtatcgagaa
    12121 ttttttttgc ttcttttttt gttgctacag aaacagaatc ctcacgagta gataaactta
    12181 tatttgagat aattttatta agctttgatg agctattaga atcatcttta aaatcaaatt
    12241 gttctggaat ttgaactttg ttttcagggt tatatattcc aaaaccattt tctttgcagt
    12301 aatcattttt tgctttacct aacaaattat caattagtat ttgaacttga gatgtattct
    12361 ttttagattt atcaatatct tctataagta aaacaagctt attatatagt tcttgtctag
    12421 cagtattgtc ttttaataag tttacaattt caagacctcc aaggcatttt tgagaatttg
    12481 aagattttat cagtgaagaa gcaatatttt ctaagtttga atcatcttgt tcaagtaaaa
    12541 tttttattac tgtttgtcta atagagcttg tctttaaaga caatagattg gttatcttat
    12601 ctaattctac atctgttagc tcaagctttc taagtagact caataccgtt tctctattgg
    12661 aaacactctt atcacttaaa cattccaata aaaattcacg ttgtctatct gtctttggtt
    12721 catttacaaa attgactata agtgaagctc ttaaatctga actcataaga tgacaatttt
    12781 ccataagcac atctataaat tgagcattca tatcgtatgc tgttaaagtc atcatacatt
    12841 taagtatttc atgagaagaa atttcaatcc aagtccatgg aaatacactt cctgaaaatg
    12901 attttgtctt tgaatttaaa atttctaaag tatgttttaa actttcaaat tgttcttttc
    12961 tagcatcaaa gtctttgtca ataggagtgt ttgacaagtc aaaattagtt tctctgtttt
    13021 gccaactata gtagtagcca acagaacctt ctacatagaa atttgtaatt acccatgcta
    13081 gtatctctaa atcatcaccc ttaatgtttt tagatgctat agaatgttta aaatatgtac
    13141 tttctgtatg cgataaaaag taaagagcta caagtttttt atatttttcc tgacaagaaa
    13201 gtaagttttc aataagagag taagagtcat atatgttgta agttgcagta gcccacaagg
    13261 caaaataaat ttcaagatta tcattgctat taattgattc tatacggaac ttttcatcag
    13321 tcaatgattt atatgaaagt tctaaacatt tacgtattat tccaggtttt tggtctgaaa
    13381 aaccaagtcc tgtccatgta tccaaggctc ttataacaga actaaatcgc tctaaattgt
    13441 tgtccaaaat agtttttaac atgtatattg atgcagaaat tgtaccctca tctaaactct
    13501 ctacaatttg ctgtctaagt ccttcttgtt gtttggctgc caaaagaagt ttagaaagca
    13561 tttcatagca tttatcacta tgactcttca tgataccaat tatcatttgt cttgtaagta
    13621 gagcagtttg attttctcca aatattactt cttctaaagc acttattact ttttgatttc
    13681 ctttgtctat ttctagtgct attttatcac tcattataga gtcatagtac aagaccttat
    13741 ttggaagagt aagataatct ataactgaaa aatcataata aattaaatca acatagtttg
    13801 aaataaacct tataatacct ctaaaataat ccacaagttt atttgagcga taccctttac
    13861 gataatatcc tcctgaatat gtataatcca tctttctttt aattaattgg caaagttctt
    13921 ctacttgttc agaagtaaat attaattcta atgcattttt taaaggtcca gaaaggagct
    13981 cgtccatatt tttaatttcg tagtagtggc aattgtagta tttctttatc atatttaaga
    14041 atttgtcttc aggttctcta taatagtatg aactattttc tatgcagtcc caaagagact
    14101 ttgctaagtc gtagtactgt tttgaagaag atttagtaaa attattttta aaattttcaa
    14161 ttattttagg atttttttct actctagtac gttctaacat ttatgtacct ccaaattatt
    14221 tattttaaaa cattcttcca gcaagcaagg taagtcttat aaaagtaaat atatctccac
    14281 ttttcagatt tatagaggaa tcgagttttt caataacatc ttcatttata agcactttgt
    14341 agattccatc ttcaaatgcc tgtaacgcta cttctattgc cttttctaca gattgtttat
    14401 tctcattgta aatagagcca aatccaactt ttccaatatc agcttgagat tcaatttctt
    14461 cattagttaa gaagtttatt attgattttt ctgggatttt ctcattatat tcaagaacat
    14521 ttttagatac aatttcagag atagcttctt ttaggcaatt gatgttgtca ggtacatcaa
    14581 aaggggtaag ttctagcata ggtttgcgtt tgccaacagc cttaactcta aaataaattt
    14641 gcataaaatc acctcgcaaa atattaatta tgtatttaga aatttaaaat ttatctattt
    14701 gttatattat atcattttgt gaattattaa tgtgaattat ggaattattt tacaaaaaat
    14761 agaaaaaaag ctatcttaaa gtctaaaaaa gcaataaaag ataactttta actataatta
    14821 tatagaatta taactgtaca tttattaaat tttaatttta gaattatttt tgataactat
    14881 ctttttttat ttataaattt tgctcctaaa tattttttga tatcttcttc aggagaaaag
    14941 tcatcaataa gtatttcttt cccagtgtct tcaaatacta caagaacttc acagtcacct
    15001 tgtaagaaaa attttctaac tgtatcttct ttaacttctc taacttttat tacattcttt
    15061 ttttcttttt caaagtcttt tgtgtaataa cttcccatca tattaattat ttttgtatat
    15121 ctattcataa aatacctcca tatgcgatta aatttaaaaa atatgttata ataattgttt
    15181 gtattaactt aataattata acaaggagta ataataatga ctagtataaa aaataaagat
    15241 attttaaatt gtatagatta ttccattaaa aataagctct ttgacaaact aaatgatgta
    15301 tataagtcct tgccagtagg aaattgttct ggatgtggaa attgttgtat ggagtcagta
    15361 ggtataaatt taattgagtt tttgaatata ttttgttatc ttgaagatag agttgattta
    15421 aaaaaaagct gtataagtaa aatattagat tattattttg aggagtatac aagaaagaac
    15481 ccatgtccat ttaaagatac taataataga tgtttaatat atgaagttag accattaaat
    15541 tgtaggatgt ttggacattg gaaaaaagag gattataata aaaatttaga taatgttatt
    15601 gagaaaaata ataactatag agagttaatg aaaaagcaat atggatttga aataaatgat
    15661 gaagtagtaa attacaggat agattattgt gatagattta ttccaaataa agattattta
    15721 agtaaatcta agagattaag cttttttgat gagcttatga tattagactc aaatatttat
    15781 tcaagtggaa atatagatat agactttagg gatagaggta tagttgaata ttttatagag
    15841 tcattacttt atagaaattt agcatataat gtgaaaataa ggatatctaa agaatacaaa
    15901 ataagaaaaa gaactataga tagaataaaa aggattgttc ttgtatagtt ttatattagt
    15961 aagtaataaa ttgtatcata aatattgtca aaatgaggtg aagaaggtga atcttacaaa
    16021 agtaaaagga aatacctttt ttataaaagg tggcacgaat acaggaatat atgtatttga
    16081 agataacaca gcacttatga tagacccagg gttatgtggt tcaagaccta ggagagtaaa
    16141 taaagtatta gatgaaaata atatacaggt tagatatatt ataaatactc atggtcatga
    16201 tgaccactat ggagcttgta atcaatttaa agaatattat aaagatgtgt gtataatgtc
    16261 atctgaatac gataaattat atatagaaaa tccagaattg ttttcaaagt atattgttgg
    16321 gggaaagagc aatgtattta tggataatat cttaaaaaat aaaatgttgg atgatataaa
    16381 aatagataaa tctatagaag ctggaaaaat tgaattaaac aatgaaatgt ttgatataat
    16441 tgaatttcag ggtcatacac ctggtagtat agctgttttg acgaaggata atgtgatttt
    16501 tgttggcgat ttattgatag gagatgaaat tttatcaaaa tacgatttct tgtttctata
    16561 tgatatacaa gaacaaataa cttcattaga aaaattaaaa aatatagatt ttgagtactt
    16621 agttttaggg catggcaagc aagttatatc gaaagaagat tcttataaat taatagaaaa
    16681 acatttgaat gctttaaaaa aatatttata tcaaataaga gagttgcttg tagaaccgaa
    16741 atctttagaa attttattaa aaaacattat aaataacaat aatttaagca ataattataa
    16801 agagtatcat ttttttaaat cttcgttagt atctgtcata agttacttag ttgatttaga
    16861 agaaataggg tatatattgg aaaatggaga attgctttac tatacaaaaa caaaataaat
    16921 tatgataaaa taaagaaggt cataaaaaac aaataaaggg tgagcaatat ggaatacgaa
    16981 aaatggaatg agatactagc accttatgaa catgcagtag aggaattgaa aataaaattt
    17041 aaaaatataa gaaaagaata tttagcaaaa ggtgaatatt ctcccataga gtttgtcaca
    17101 ggtagaacaa aaaaaatatc ttccataata tctaagttaa aaaggataaa tgcaaaagat
    17161 atagaaactg aaattgatga tattgctggt ataagaataa tgtgccagtt tgttgaggat
    17221 atatatgcta tagttgattt gataaaagta agaaatgata tgactataat aggagaaaaa
    17281 gattatatta caaattacaa agatagtggt tatagaagct atcatgttat aataaaatac
    17341 cctataaact ccattgcggg ttcaaaggaa attatatgtg aaatacaaat aagaactctt
    17401 gcaatgaatt tctgggctac aatagaacat tcattaaaat ataaatatga ccattacata
    17461 cctgagactc ttgctgaaag gcttagaaga gcatctgatg ctgcctttct tttagaccaa
    17521 gaaatgagtg aaataagaga ggacataatg aaagctcagg ctatgtacca aatgaagtct
    17581 atagctatca gagatactct aaatagaata caagagttat atgacttggg tgatacacat
    17641 aaagctatgc agtaccaaag aaaacttgat agaactgaaa cagataaaaa tataactgaa
    17701 attttggaat taaaacaaga aatagatata ttattagagc aatataagga tactaaggta
    17761 gatgataaag tagttcagta aaactacttg tagaaaattt gctaaatatt aatggggctg
    17821 cctcttaatg gaaaataatt tctaaaaaga gacagcctat ttagtgtaat taagaaagga
    17881 atgatattat gagtttgtat gctataggtg atttacattt ttcaacatca gtcaataagc
    17941 caatgaatat ctttggaagt aattgggatg gtcatgaaaa gaaaattata gataattgga
    18001 aagaagttgt taaggaagaa gatatggtct tagtactagg agatacatct tggggaatta
    18061 atttatcgga agctaaaaaa gatttagata taataagcaa acttccaggt cagaaaatac
    18121 ttataaaagg aaatcatgat tactggtgga caaccgttac aagtttaaat aagctatatg
    18181 aagacatgcg ttttattcag acaaattttt atgaatataa agattatgca atttgtggag
    18241 gtaggggctg gatatgtcct aatgatgtca aatttgatga gactgatgaa aaagtttata
    18301 aaagagaaga gcatagactt agactatcat tagaatctgc tcgtaaaagt ggtcactcaa
    18361 aaataattgt gattactcat tatcctccta cgaatgataa attggaagaa tctttattta
    18421 caaagttatt tgaagaatat aatgttgaaa aggtgattta tggtcacttg catggtaaag
    18481 aatcttttaa aatgggattg aaggggattc gaaatggagt agaatataca ttagcatctt
    18541 gtgactatac agaatttaat ttaataaaag ttcacgatta aaaaacataa attggtaaat
    18601 actataagat acatgattaa aaataaatat ttgagggatt tcggttttga gaaaggagac
    18661 acgacttatg aggtggatat tagtttttat atttttatat cttattcctt tagtagtgat
    18721 attcagaaat tacaagaatt ttaagaggtc ttgtatctac agtagtattt atgtggtatt
    18781 agctacaaca ataatgataa gtaatattta tatgagtgga cttaataaaa taaaagagtc
    18841 tatgtattat cacaattata tttctgatga gacatatgat gaaaagtatg tatcaaattt
    18901 taaggaaaaa gaaagtactg atttaaaaca ggataataaa aagaatgaag aaatatcaaa
    18961 taataaaaat ttaaacaaca aacaagatag aaatatacaa aataaagaaa gtaatgaaga
    19021 aggaagtaat gatataaaag aaaagaataa ttctgatagt aatgtttcag tgaataataa
    19081 atcagaaaaa caagaagata atacaaaaga aaataataaa tatacaagta aagaaaaaaa
    19141 tagtgaagat ataaaaaaaa tagatatgga aagtatagga atttttaaga aagaaattta
    19201 taatatagaa agagcagctt tagttccaat gagagaatgt ataccttaca ctaaggatat
    19261 agcaaaaaat ataactaaat tatctagtat aaaaaaagat gttacaaatg ccagaaacaa
    19321 gtgtaaagaa gttgtaaaag aatatgaaaa tatgcagatt ccagaacttt ctaaggagaa
    19381 gtatacagaa acattgagta atgctagaga tgacgtaaag aaagcatatg agcttagaga
    19441 aaaatctatg gaaagtgctt tgaaattaat aaatactaaa agccctaaat atatagggaa
    19501 gataacagaa tatcttgatt tatcagataa gcagatagaa agttttaaaa atagattgaa
    19561 cgatttaaaa gaagaaataa ataattcaga aacaaataat attaattaat aagatttaag
    19621 gatataagtt aaaagggaga ttatgatgaa taaacagagt ataggaaaac taaatatgtt
    19681 ttttatgggg attactcaaa gaaaccttga taatagggat ttttttattg agttagaggt
    19741 gatttttaaa tctggaagaa aagagtttaa aggaattgca atagaggaag ataataaata
    19801 taaatttaat tttaaaggaa aatcagattt atatacgttt aatgagttgc ttaagaatat
    19861 ttctaaagag gcagaaaatt atgatggatt agtatttaaa tatgttgagc gaggaactat
    19921 tgttgtaatt gaaggagaca ataagaaggt aaatgtaaaa tatttagaca ataaggaaga
    19981 agtacctaaa atagatgaat ttacggcatc tcaaataaaa aacagagatt attatgtaaa
    20041 agtaggacaa gcaaatgcac ttttaaaaga aattggagta cttacaaaag atggtaagat
    20101 aaaaaatgat aaaataagaa aatacaatca gatagaccat tttgttgaat tgatagatag
    20161 tattttaaaa gaaataaagg ataaagactg tataactatc ttggattgtg cttgtggaaa
    20221 atcttactta agctttgtct taaattttta tataaaagaa gtattgaaga aaaactgtta
    20281 ttttatagga atagattatt cagatgtagt tatagaagca tcaaaaaata tggctaaaaa
    20341 cttgggttat aaaaatatgt catttataaa agaggatttg actaattata cacctaatag
    20401 ggatgttgac cttgtaataa gtctacatgc ttgtgataca gctacagata tggcaatagg
    20461 tctaggaatt agagcaaaat ctgaagctat agtagtagta ccatgttgtc ataaggagtt
    20521 attagggcaa tatagatatg aagctatgga accaatatta aaacatggtg tatttaaagc
    20581 tagatttgca gatttaataa ctgatggttt aagaacattg ttattggagg gcaatggata
    20641 tgatacttct gtagtagaat acatatctcc acttgataca ccaaaaaatt taatgataag
    20701 agcgataaaa actaaaacga ataatgacaa agcattaaaa gaatataaag aactgaaatc
    20761 acaatttgga gtggaaccaa ccttagaaaa acttatatat tagttaaaaa tgtaaaattt
    20821 acgaaaagct tgcttaaata tgcaagcttt ttggtattat ataggtatag tcatatccag
    20881 agttttgatt tataattaaa gctgtgctat aatatttgat taatcaaatc aataaatgtt
    20941 acatggaggt aaaaatgaac aaattgaata tatgtattga tatagatgga acaataacaa
    21001 gcccttatca ttttcttcca tacctaaatg atatctttaa taaaaatata actgaagcag
    21061 agtgtataac acataattgg gaagaattgt atggttcggg aataagagat gtgtatgcgg
    21121 agtttaataa taagtatata cactcatatg atgaagcaaa gattgtagag ggtgctacag
    21181 aggtaattag cacattatct aaaggacata atttatcttt tgtaacggct agacatgagt
    21241 gtttaactga tgtaactaaa aattggctat cgagacaagg attttcagat atagatgttt
    21301 acttattagg aagtgattat aaagttgaaa aggcaagaga actgagttgt gacatattta
    21361 tagaagataa tcctttaaac tcagtgcaac tagctgatga tggtgttaaa gtaatacttc
    21421 tggatactaa ctataataaa gatgttaaac atcaaaatat agttagagtt agtaattgga
    21481 tagatattga aaagattata aaacaaggta tttaaagatt tgtagattga aagggggagc
    21541 atatgataga tttaaaaatt gaaaatagaa aaggaaaaat ccatgtaaag agcagtgaaa
    21601 taaaagacat tttagaatta cgtccagact tcgaatatgt acaagatata tcaaatacta
    21661 taaatcaaga aaatatattg gtatttgatt gccagttgac aggaaattct tttgatatgg
    21721 atgatttaga tatagaagaa atattggaag agttaggtga agaaatagat gagtcttatt
    21781 tcagtgtttt atttgaagat gtaagagcgt atttaaaaga tgctactgat gagatagaag
    21841 cagacttaca ggataattac ttatttgata atttgagatg ttattttgat atatacaata
    21901 taaatcaaga atttacagat tttaagtttg tatttttagt ttcttttaaa gatataaaaa
    21961 tttcttcatt agcaaaccta gctaagattg tttctaagag acagcttata ggtgcatcta
    22021 agttttatag ttaaaatgaa atattattat aataaaagct agtaaccttg taaaaatata
    22081 ggttactagt tttttattta ttcattttca caaaatttca gaaaactatt tacattctaa
    22141 aaaaagtaat gtatattaaa cataatgtac attataatgg ataaaaagtt tctattaaat
    22201 tactaagttt atttaataat caaaataatt tatcttatat tagtatgtat tagggggtat
    22261 ttatgcaaag tttaaatgaa ataattgctg aaaatttaaa aaagataagg aaagaaaaac
    22321 atcttagttt agacaagatt gcacaactta gtggtgtaag taagagtatg ctatctcaaa
    22381 ttgaaaagtg tgaggtaaat cctactatat ctactttgaa gaaaataact aatgggctaa
    22441 aaatctcatt tacatcattg atggagaggc aggaaagtga catagaattg attcaaaaaa
    22501 gtgatataga ccattttatt gaagataatg gaaagtatat aagttatcca atatttccat
    22561 ttgactccaa aagaagattt gagatattta tgattgaaat agaagaaggt ggaaatttag
    22621 attcaaatgc tgaacttcca ggaacacaag agtttataac tgtttttagt ggcgaagtaa
    22681 ccattaaaat aaatggagaa gattacattg tatctagtgg aaattctata agatttaaag
    22741 ctgatgtatc acatatatat agaaactcag gcaaaggtat agctaaaatg agtatggtag
    22801 tatattatat ataaataatt taatggaatt agagtgatat ttagatgatt ttaggtatga
    22861 agatatatta tatttaagtt ataggagtgt gatttatgga tgaataataa aaaagcagtt
    22921 tttttctttt gcagtgattt aaagaaagac ccagtagcca gtaatgtgat aaaatgttgt
    22981 gaagaaataa tggatttaaa tcaaactgat attgttattg atgataattt tgtattagag
    23041 tttaaggata aaaacaataa cttatttcat tttgtaaaaa caaaagatgt aataagtcat
    23101 aattataaat attatcttcc aattttaaat agacatttta gagattatga ttttgcagga
    23161 gttgtaaatt ggcatgaggg agaaaatgct ccagaacata tcctaacagc tcatacaatt
    23221 ggagatgttc caacaggaga atttggaaat tcaaatccaa gatactttaa aaatctaatc
    23281 aatgctattg aggatataaa aaatgaaaat ctacttgatg aatttactac attaacagaa
    23341 gcaactcact ggtctggaac aacatatggt gaagaatcta aattaattac agaatattct
    23401 gtacctatgt tggatattga gataggaagt agtagtgata gttttaataa tagtatagca
    23461 atacaggtat tggcaaaatc attaattaga gtatttgatt gtgatgaacc tttgaagact
    23521 ttattatgtg ttggaggggt acattttgag aaatctttct cagatattat aaaaaataaa
    23581 gaatataaca tatcaattgg acatgtattg ccaaatcaat ggattgtaag tggaatgtat
    23641 gatgatgaat cgggatttga gaaactggaa aagtgtataa atagtattga aggaggaatt
    23701 gattgtatag tttttcatga taaattaaaa ggtacctata aagagcaatg ccgtaaacta
    23761 ggtgaaaaac ttaatgtacc tgtatttaaa cataaaatat taaaaaatcc aaaagactta
    23821 tctatatggt agttttatac agttaatata acaataagtc ggattaattt ttaagcgagg
    23881 tcaaaaatga tattatctta ttttgcatta ttaattagag tagtgctatt agcttttgaa
    23941 agagtagttg taagattatt aggtgatgaa gaaggagata tttataaaaa tatagcttca
    24001 tcatttctat ttttctttat agggggagta tgtttacttc catttagcat aatggataga
    24061 gttagtgatt ggtcgttttt aataccatgt tatataagta gtttagtcta ttcaattggt
    24121 tcagtagcgt atgtaacgtc tttagcaact ggggaagttt cacttgttac tccaataaat
    24181 agtttaaatt cattgttttt actgctttta tcagttatat ttttaggtga aggtttaagt
    24241 ttagcaaaag ttgcaggaat cataattatg attggtggag tgtttatatt aaaaaaagta
    24301 agctcttttt taaagaatgt ctctgtaatt tttaacaatt taccatgtag attaatgttt
    24361 ttatacatat ttttgcagtc agtaggaaga gtattggata aggctttttt tgtacaagta
    24421 tctcctatat tatattcaac tatactgtat tttttcgtag gtttaaattt atttatcttt
    24481 ttagcattta aaaagaaaca aaaaataatt tgtgagattt ttactaataa aaagggactt
    24541 tcaattttaa gtggttctat taatggatat tcttatttag cattattaat tgctttaaat
    24601 aatctagaac ttagtatagc agagccattt tctcaagtat ctatgataat aactttaata
    24661 cttgctcatt ttatattcaa agaaaatata aaagaaaaaa taccaggttc aattttgata
    24721 ctaattggtg ggtggctact gttactttaa ttgacataaa aaatgaatta taaaggtgct
    24781 attagttagt atcagaaaat ttaaaaaagt attgacaatt cttttaggca aatgttaata
    24841 taataataca aaatagtata aatagaagac atgttactgg taatgcaggc aggatcgaat
    24901 atattgcttt gatttttcaa ggtgtttata taggttctgc cttttttgca tcttgaatgg
    24961 ccattcataa aaaattatgg agaaggagat tacaagatga attataaaaa aactgccatt
    25021 gacattattg aacaagttgg tggttcaaaa aatattttag ctttagaaca ctgttcaact
    25081 agactacgct ttaagttgat tgatagaagt aaagtcaatc aggatgcttt aaaaaaagta
    25141 caaggtgtta tgagtatagt taatggggca caatttcaag ttgtcattgg aaatagtgtt
    25201 gttgatgtgt atgatgaaat tttaaaagtt tgccctttag atacaaatga tagtactgta
    25261 aaaactgaag aaaaaataaa cttaggaaca agatttatag aatttattat taatattttt
    25321 caaccactga tttttgctat tgcaggagct ggtattttaa aatcactgtt gatgttatta
    25381 gcaatgttta atattttaaa atcagattct actatatata cattattagt tgctatttca
    25441 gatgcaacat tctatttcct acctcttatg gtagctgtaa ctactgccaa tgtattgaaa
    25501 tgtaatcgtt tagtagctat tgccgctgta ggatacttat tgcttccagc aacaacaact
    25561 gctttaagtg aaggtgtcga actatttgga tttacaattc caaacattgc ctataatgca
    25621 caggttttcc cagctatttt atgtgtgtct ttcttggcaa caatggagaa aatttttaac
    25681 aagtattcac caaaaccaat tcgaactttc tttgttccta tgatgtcttt ggcaattact
    25741 gttccaatta ctctaactat tttaggtcct ttaggatata acgttggtac aatttttaca
    25801 accattattt tattcttata taacaaaatg ggattcttag ttgtaggatt acttgctgct
    25861 tttcttccat ttatggttgc aacaggaatg cacaaagcac taatacctta ttcaattaat
    25921 acaattggaa agttgggtta tgaagcttta tatatgacat cttcattagc ccacaatatt
    25981 tctgaaagtg gtgcttgttt tgcagtagcc ttgcgaacaa aagatgaaac attaaaacaa
    26041 acagcattat ctgcaggaat ttctgccttg atgggaatta cagagccagc tttatatggt
    26101 attactttac aacataaaag agcaatgtta ggtgttgtat tctcaagtgc aatttctggt
    26161 acatttttag gattatttgc agtaaaagga tttgtaattg ttggaccagg gcttgccagt
    26221 atgagtatgt ttattgaccc aaacaatgga aacaatttga tttttgcaag tattggtttt
    26281 gttattgcaa tattaggctc gtttattatt acactgatta tttggaagga agatacaaat
    26341 acagtagagt catcaattgg agatgttgtt gaagaagagc tagaagaaga aaaagaagta
    26401 aatatcttag taactccagt agaaggaaaa gtaatagatt taagtaaggt taatgatgaa
    26461 ctatttgcaa gtaagacttt gggagatgga gttgcaatta taccgaccaa tggaaattta
    26521 tacgcacctt gtgattcaga agttgtgatg ttatttgaaa caaaacatgc aattggttta
    26581 agaacaaaaa atggggctga gattttgatt catattggaa taaatactgt aagtatgaat
    26641 ggagatggat ttaaaacatt tgttaagaca ggcgataatg taaaagaagg agatttatta
    26701 attcaatttg atttagacaa aatctcacat gctaatttag attcaactgt tatgattgta
    26761 aacaataatg gagcagatta tgcttataaa gtgttaaacc agtcttatgg caatgtaaaa
    26821 aaaggaagta tcttgtttga tgtaaaggga ggaatataaa tatgagaaag tttccagaag
    26881 gatttctttg gggaggagct acagctgcta atcaatttga aggtggttgg aatttaggtg
    26941 gtaaagggtg gtctgtatca gatgtagcaa aggcacactt tgatgcagat gtgaaagatt
    27001 ataaatctaa taatgaaatc acaacaaaag atatagaaga aggattagca catcctgaag
    27061 atgaagtaaa ttatccaaaa cgtcatggta gtgattttta tcatcactat aaagaagata
    27121 ttgctctaat ggcagaaatg ggatttaaga catatcgaat gagtattgct tggtctcgta
    27181 tttttccaaa tggagatgat aaagagccaa atgaagaagg tttacagttt tatgatgatg
    27241 tatttgatga gttgataagt tatggaattg aaccacttgt tactatgtca cattatgaac
    27301 caccattaaa tatcgtttta aactatgatg gatggtattc acgacaagtt atcaatatgt
    27361 ttgttaggta tgtagaaact atctgtgaaa gatataaaaa caaagtgaaa tattggctta
    27421 catttaatga agttgattct atgattcgtc atccgtacac tactggtggt ttagttcgag
    27481 accgttttaa ggataaaaac tttgaggaag ttatttttca agctatgcat catcaatttg
    27541 tagctagtgc ccttgcaaca aaaatttgtc atgagattat tccaaattca aaagtagggt
    27601 gtatgttaac aaaattaacg tattatccat atacatgtag accagaagat gttttggcaa
    27661 ctcaacaaaa aatgagaagt atttatgcat atagtgatac gcaggttttt ggtgagtatc
    27721 cagtatattt actgtcgtat tttaaaaata ataacattca aatagtaaaa gaagaacatg
    27781 atgatgaaat tatgaaaaag tatccagtag attttatttc attctcttac tatatgtctt
    27841 cttgtgaggc agctgataca actggattag atattacacc tgggaatacg ttattagctg
    27901 taaaaaatcc ttatttagaa atgagtgaat ggggttggca aattgattca ataggtctac
    27961 gtatatcttt gattgaatta tatgatagat acagaaagcc tttatttata gttgaaaatg
    28021 gattaggagc taaagatatt ttaactgaag ataaaaaagt tcatgaccaa tatagaatta
    28081 attatttaaa agaacacttt aaatgtatgt tagatgcgat tattgaagat ggtgttgaac
    28141 tttggggata tacttcatgg ggttgtattg atttggtcag tgaatcaacg aaacaaatgt
    28201 caaaacgtta tggatatatt tatgtggatg ctgatgatta tggaaagggg acatataatc
    28261 gatataagaa agatagtttt tattggtata aaaaggtaat tgaaaataat agtatagatt
    28321 ttaaatgacc aatagaaggt gagcaaataa aatgaactac ataataaaga aagttttgaa
    28381 ctcgagcgtt gttttagttc atgacacaaa ggataatgaa tttattttgc tagggaaagg
    28441 aattggatat ggtaaaaaaa caggagaata tatttgtggt tccaatgata atcaaatgtt
    28501 tgtccctgtt gaaaatacaa aatcaaaaca atttttagaa ttaatggatg atattcctgt
    28561 cgacatttta aagataacac aggaaataat agtagaggca gaaaagttat tgaactcatc
    28621 ttttaataaa aacttatact taatattagc agaccatttt aactttgcaa ttgaaaggat
    28681 gcgtaaagga ataaaaatta caaatcgagt attttgggaa ataaaaaatt attatccaaa
    28741 tgagtttaag gttggaatgg ttgcaattta tatggtagag gagagattgg gcattcaatt
    28801 accagaggaa gaagcagcta acattgcttt ccattttgca aatgctatgg cttcagatgg
    28861 aaattcatat gatacgatta agtatgccaa agtaattgga gaaataatta atatttttat
    28921 tttttctttg aatagaacct tagataaaaa gagtatgcat tatatgagat ttataacaca
    28981 tataaaattt tttgtggaaa gatttttttc agatagtatg ttaagcagtg gtgatgattt
    29041 attatttaat caaatgaaaa ggtcaaatcc aaaagaaatg ttaattgcat taaaagttag
    29101 agatttttta gaaaagaaat atggaaaaaa gttaacaaat gaggaaatag ctttcttggt
    29161 tgtccatatc gcacgagtta agcaatagag taaattacag caatagagtg aattactaat
    29221 attatcttat acgtctacat ggtagaaaat tgaaagaagg taaagtgtat aaagaaactg
    29281 agacatatta ttttgttgtt cattatgttt attttatgag tgtatcctgt taaaaattta
    29341 agttaatatt tataattaaa atatgcaaat agttaaaata agtttatgtg gttatgaatt
    29401 tattttaact attttttgtt taatggaaaa tatgctttat aactaaaatt ttatttttaa
    29461 ttaattataa tacaaaaaac tttataaaat cttcagaatt tcttaaagaa tatgtaagta
    29521 acataagata tattatattt agttggtaat ataaaggggg caatatttat gaagaataaa
    29581 aaattcaatg ttataacact gataatactt gataatcata tttatgccat taataaagag
    29641 cagattagta ctaattcaaa aagaatttac tttgaaaaaa gtggattttt cagtgattat
    29701 aagtgaataa atatatataa acatttaata aatttagaag ttaaatgttt taatacgaaa
    29761 ggatacacat atgataaatt tagaagaaaa gtatttaaca cgaaaagaca catatatgat
    29821 aaaaattcta gaatataatg gacatattcg aaactggaaa gttctttgtg aagaacttgg
    29881 aatcgattct tcattatgta gagatgagcg tgaacgagca attttagtgg aagcatataa
    29941 gacatgggga tatgatatgg caaatcacat gcatggaatg tttgcttttg cattatggga
    30001 tactgtggaa aagaaactct tctgcctaag agaccagttt ggagtaaaac ctttctatta
    30061 ttatgagact gaaaatggga agcttctcta tggttcatct attcgtaaga ttatggagca
    30121 accaggattt gtgaaagagt taaatgaaga catgttacag atttatatgt ctttcacata
    30181 tgtagcaggt gaaaatacat tcttccgtgg agtaaagaag cttatgccag gacattacct
    30241 tgtctatcag aataaaacag tatgtattgg tcgttattgg aaacctgaat ttcatcctga
    30301 ccacagcaag tctattgagg aatggacaga tgaaattcat acaacacttc agaaaattat
    30361 gccagaggta aaatcagaga atgaaactgc agagttattc ctatcaggag gtgttgattc
    30421 atcttatata ttggcaatgt cagatataga aaaaacaggt tcatgtggtt atgaggaaga
    30481 gcgttttgat gaatcaaaat tagcacaaca gacagctaat attcttgggt gtaaaaattc
    30541 gagatatata attacacctg aagagtattt tgcgtcagta ccttatgtaa tgtaccatat
    30601 ggagcaacca actggagatg catctgctat cgtttttgct attggatgca aggcagcagc
    30661 tgaaaacaca aatatctgtt actctggaga aggagcagat gagttttttg gtggatataa
    30721 tatataccat aaggcagagt gttatggaga gaatttgaag acattttata ttggaaatac
    30781 aaacattatg aatgagggtg agaaaagaaa aattcttaag aaatacaatc ctgatgtgct
    30841 tcctattgaa gtggtaaaag gaatttatga agaaacagaa gaactagata cacttactaa
    30901 catgtcaaat gtagatattc aaatatggtt ggaaggagat atttatttta atatagataa
    30961 aatgagtact gcagttggat tggaagtcag aatgcctctt acagatacaa gaatatttga
    31021 tattgcatcc agaataccat cagaatataa agtgaaagga aaagagaata agattgcctt
    31081 tcgtacagct gcatcaaaaa cattaccaga agagattgct tttagaaata aattaggatt
    31141 tattgtgcca attcgtatat ggatggctga tgaccaatat aataaggaca tccgagataa
    31201 attcaatagt gagatagcag ataaattctt taacatagat gagattaatg agatttttaa
    31261 tgactacatt agtggaaact ctgataattg gagaaagatt tggatgattt acacattcct
    31321 agtgtggtat gaaatctatt ttgtaaaatg ttaatacaag aggaagaatc acctgaaaga
    31381 ccattcaggt gattcttaat gttttataat taatgtttta taattttact tgctaattct
    31441 tatgtctaac ccttaatggt atatcaagtt tttttgccag ttgtttagat tcttctattt
    31501 cttctggaga tatttcatct actactgaaa aagctacttc ttttatatat tttttgcaat
    31561 cttttgcaaa atctaacata taatcaaatg atttttctcc aaactttggt tgagtaactc
    31621 tattataagc ttctttattt ggggcattaa gacttattga tactgcatct ataacatctt
    31681 ttaacagaat agctgttttt ttgttatgta ttaaatcact tagaccattt gtatttattc
    31741 ttatttttat gatacttttt tcttttataa actttgctac ctctatcaat tcatttattc
    31801 tcattaatgg ttcgccatat ccacaaaata cgatttcatc atagtcgtct aaattgtatt
    31861 tattgaaggc ttcttttact tcatctacac ttggctcatg ctccaaccat aaactaccac
    31921 tatttgcaac ttcatctttt tcgtttctta tacaaaaaac acaactacat ggacatgtat
    31981 tagttatatt tacatagata ctattttcaa ttgtatataa gatattcata attttccctc
    32041 cataaattta aattcttaat taaaataacg ttttttaaaa tcaagtttat caagtgccat
    32101 acctaagatt ataaaaacaa taaaacttcc tattggctgt aataagccaa gtaagctcat
    32161 tacaaatgca cttgtaaaac ttccaataat tataccttca gcaaacatgt ataaaactaa
    32221 tcctactata cctgctacaa ccgaagcaac tatatttctc ttatttatta tcttgtcact
    32281 tttagaagtg aaaaataata caagtattgg ttttatgatt atagttggta ttacccagat
    32341 agcagcacct gtagataaat cagctagacc agcaccaatt gcagaagcag ctatagcata
    32401 gtttgttggc aaaatagttg cagctagata aataaaagca tctcctatat gaacatatcc
    32461 attgtttcca ccaactggaa tatgtaatat atatgctatt gtcaggcata ttatggatgc
    32521 aaataatgct gaagtaacaa tataggtagt ttttttagaa gtaactttat tcattttttc
    32581 caatatactc cctccctaaa aatccagagc taacataatt gttatgtttt cttataaata
    32641 tattaatatt aatcatacaa ttttcatagt ttgttaggta ttttttttgt aaaatacaga
    32701 ttgtacccat tcaaatgtat ataattagaa aagtaaaaat aggtaaaatg tatagagtag
    32761 gagtagttag aataagttaa tataaattta atttggtatg aataagagga gtacaagttt
    32821 aatataaaaa ataatataag agagtctact caatatatac tgagctgact ctcttatatt
    32881 tgggaaatta aaggctattt tgttagataa tagctaatta atgaaaaaat atatttataa
    32941 aatactaatt tactctatta gtagcagttc ctgtttttat aacttctaca gcactactta
    33001 aactagaata aactatattt tcaatcgctg tactagtgaa gaaaccaagg tgatgagtga
    33061 atataacttg ttccatagaa agaagtttat ttatttctgg gtcagttaat tctccaggat
    33121 tcattttttt gtttaagaac aatccttcag tttcaaatgt atcaagggca gcagctctaa
    33181 tttttcctga ctctagtgct tctattaaat cccctgtatt aattaaacca ccacggccag
    33241 tatttactat gtaagctcca tccttcatta tagctagagt atctttattt atcatatgtt
    33301 ttgttccttc aagtaaagga gtatgtaatg ttataaggtc agcttctttt agaaggtctt
    33361 ctaaagaatc tttgtaagtt aatatatcgt ttaaatcact atttggatat tggtcaaatg
    33421 caattacatt agctcctagg cctttgaata attttgcaga agtagcacct atttttcctg
    33481 tacctataac accaactgta atagatctaa cttctgttcc aagaagttca gctatccaac
    33541 ggtaatcacc ttcacagact tttttcttta ctagaggagt ctttcttaaa aggttcatag
    33601 cttgagtaac agctaattca gctattgcat taggtgaata agaaggaacg tttgtaacga
    33661 taagtccatt ttcattaact aaatcaaaat gtatcatgtc aacccctgca gttcttgaag
    33721 ctataacttt aaccccagca tcttttaaag tttcataaat ataaggatta tctatatagt
    33781 tagtttgttg tatagatata ccatcatacc ctttagcttt aactacattt tcttcagtca
    33841 tgttttcagg ataaatatcc acttgaacat ccttatgttc ttcagaccat ttttttatta
    33901 ctggttcttc ataatcgcgt gctccaaata ctagtatttt catatcaata ccctcctgta
    33961 attattaaat tattatggta atttttcatt tagaaataat atgtagcata taaggttata
    34021 ttttttatac aaaattttta aggttaaaaa tttagttttg aaattgtttt ccctgtgtta
    34081 ttttgatatt tagtaatttt ttatttaatg taataattat tctaaaattt atcaaagaaa
    34141 ttgttatttt ttagattaaa tattattaaa aaattatcta agtttgaaat tagttaacta
    34201 acttgctgat taattacaat gataacatgt gtttttgagt ttagcaatga aaactttttt
    34261 tgaaatgtca agctttttca taaaaaaata tataaaaaaa acttttataa gcatagaaag
    34321 aatagcaaaa tgcaatggat agtggcaaga tgccacgata tgaaaaagat tattcaattg
    34381 catattgtta aaaaacattc aaatcaagcg atattttgat taaatataaa gttggcacga
    34441 taaatgctta acaatatagg tgtaagacaa taaaacaata aaaaataatt ttaataattt
    34501 ttaagttatt ttagataaga ttaggaactt tgacatcaga cagttaatat cagaaaaaag
    34561 tattttatga gtgatttaat cgaaatttta taattgatac tattaaggag gaaaacgtta
    34621 tgcttttaga aggagttaaa gtagtagaac tttcaagttt catcgcagca ccatgttgtg
    34681 caaaaatgtt aggtgactgg ggtgcagagg ttattaagat tgaacctata gaaggtgatg
    34741 gaataagagt tatgggtgga acatttaaat ctccagcatc agatgatgaa aaccctatgt
    34801 ttgaattaga aaatggaaat aaaaagggtg taagtattaa tgtaaaatca aaagaaggag
    34861 tagaaatatt acataaatta ttatcagaag cagacatatt tgtaactaat gttagagttc
    34921 aagcattaga aaaaatgggt atagcttatg accaaataaa agataagtat ccaggattaa
    34981 tattctctca aatattagga tatggtgaaa aaggaccttt aaaagataaa ccaggatttg
    35041 actatactgc atacttcgca agaggaggag ttagccaatc tgttatggaa aaaggaacat
    35101 ctccagcaaa tacagcagca ggatttggtg accactatgc aggtctagca ctagcagcag
    35161 gaagtttagc agcattacat aaaaaagctc aaactggtaa aggtgagaga gtaacagtaa
    35221 gtcttttcca tacagctata tatggaatgg gaacaatgat aacaacagca caatacggaa
    35281 atgaaatgcc tttatcaaga gaaaatccaa acagcccatt aatgactaca tataaatgta
    35341 aagatggaag atggattcaa ttagctttaa tacaatacaa caagtggtta ggcaaattct
    35401 gtaaggttat aaatagagaa tatatattag aagatgatag atataataac atagattcaa
    35461 tggttaatca tgttgaagat ttagttaaga tagttggaga agctatgtta gaaaaaacat
    35521 tagacgagtg gtcagcttta ttagaagaag cagacttacc atttgaaaaa attcaaagct
    35581 gtgaagattt attagatgac gaacaagctt gggcaaatga cttcttattt aagaaaacat
    35641 acgatagcgg aaatacaggt gtcttagtta atactccagt tatgtttaga aatgaaggaa
    35701 ttaaagaata tacaccagca ccaaaagtag gtcaacatac tgtagaagta ttaaaatctt
    35761 taggctacga tgaagagaaa ataaataact ttaaagatag taaagttgta agatattaat
    35821 tagtaattct agatttttta aaaggagaat gctaaagatg tacacaatgg gattagatat
    35881 aggttcaact gcatcaaagg gagtaatctt aaagaatggg gaagatattg tagcttctga
    35941 aacaatatcc tctggtactg ggactactgg accatcaaga gttttagaaa aattatatgg
    36001 caagacaggt cttgcaagag aagatattaa aaaagttgta gttacaggat atggaagaat
    36061 gaactattca gatgctgata agcaaataag tgaattaagc tgtcatgcta gaggggtaaa
    36121 tttcataatt ccagagacaa gaaccattat tgacataggt ggtcaagatg caaaggtatt
    36181 aaaattagat aataatggaa gactattaaa ctttcttatg aatgacaaat gtgctgcagg
    36241 tacaggaaga tttttagatg taatggcaaa aataatagag gttgatgtat ctgaactcgg
    36301 aagtatatct atgaattctc aaaatgaagt atcaataagc agtacatgta cagtatttgc
    36361 agagtctgag gttatatcac atttatctga aaatgcaaaa attgaagata tagtggcagg
    36421 tattcatact tcagtagcaa agagagtttc tagcctagta aaaagaatag gagtacaaag
    36481 aaatgtagtt atggttggtg gagttgctag aaatagtggt attgtaagag ctatggcaag
    36541 agaaatcaac acagaaatta ttgtacctga tatacctcaa ttaactggtg ctttaggagc
    36601 agcgttatat gcttttgatg aagcaaaaga atcacaaaaa gaagtgaaaa atatataaaa
    36661 agagggatga aaatgtctga aaaaaaagaa gctagagtag taattaatga tttattagct
    36721 gaacaatatg caaatgcatt taaagctaaa gaagaaggaa gacctgtagg ttggtcaaca
    36781 tcagtatttc ctcaagagtt agcagaagta tttgacttaa acgtattata tccagaaaac
    36841 caagcagctg gagtagcagc taaaaaaggt tctttagaat tatgtgaaat agctgaatct
    36901 aaaggatatt ctattgacct atgtgcatat gcaagaacaa attttggtct tttagaaaat
    36961 ggtggatgtg aagctttgga tatgccagct ccagatttcc tactttgctg taacaatata
    37021 tgtaaccaag ttataaaatg gtatgaaaat atttcaagag aattagatat acctttaata
    37081 atgattgata caactttcaa taatgaagac gaagttactc aatcaagaat agattatatt
    37141 aaagctcaat ttgaagaagc tataaaacaa ctagaaatta tatcaggaaa gaaatttgac
    37201 cctaagaagt ttgaagaagt aatgaaaata tcagctgaaa acggaagact atggaagtat
    37261 tctatgagtt taccagcaga ttcttctcct tctccaatga atggatttga cttatttact
    37321 tacatggctg taatagtttg tgctagaggt aaaaaagaaa ctacagaagc atttaagtta
    37381 cttatagaag aattagagga caacatgaaa actggtaaat cttctttcag aggggaagaa
    37441 aaatacagaa taatgatgga aggtatacct tgttggccat atataggata caagatgaaa
    37501 acattagcta aatttggagt taacatgaca ggtagtgttt acccacatgc ttgggcatta
    37561 caatatgaag ttaatgattt agatggaatg gcagtagcat atagtactat gtttaacaat
    37621 gtaaacctag accgtatgac aaaatataga gttgattctt tagtagaggg taaatgtgat
    37681 ggagcattct atcatatgaa cagaagctgt aaacttatga gtttaataca atatgaaatg
    37741 caaagaagag cagctgaaga aactggatta ccatatgctg gatttgatgg tgaccaagca
    37801 gaccctagag ctttcactaa tgctcaattt gaaacaagaa ttcaaggttt agttgaagta
    37861 atggaagaaa gaaaaaaact taatagaggt gagatataat ggaagctatt ttatctaaaa
    37921 tgaaagaagt agttgaaaat ccaaatgcgg ctgtaaaaaa atataaaagt gaaactggta
    37981 aaaaagctat aggttgtttc ccagtttatt gcccagaaga aattatacat gcagctggaa
    38041 tgcttccagt tggtatatgg ggaggacaaa cagaattaga tttagctaaa caatatttcc
    38101 ctgcatttgc atgttcaata atgcaatcat gtttagaata tggattaaaa ggtgcttatg
    38161 atgaattatc tggagttatt ataccaggta tgtgtgatac actaatttgt ttaggacaaa
    38221 actggaaatc agcagtacct catataaaat atatatcatt agtacaccca caaaatagaa
    38281 aacttgaagc tggtgtaaaa tacttaatca gtgagtacaa aggcgtaaaa agagaacttg
    38341 aagaaatttg tggatatgaa atagaagaag caaaaattca tgaaagtata gaagtttaca
    38401 atgaacatag aaaaactatg agagactttg ttgaagtagc ttataaacat tctaatacta
    38461 taaaaccatc aataagaagc ttagtaatta agagtgggtt ctttatgaga aaagaagaac
    38521 atactgagct agtgaaagat ttaatagcaa aattaaatgc tatgccagaa gaagtctgtt
    38581 ctggaaagaa agttttatta acaggtatat tagctgattc taaagatata ttagacattt
    38641 tagaagacaa caatatatca gttgtagctg acgacttagc acaagaaaca agacaattca
    38701 gaacagatgt accagcaggt gatgatgcgt tagagagatt agcaagacaa tggtcaaaca
    38761 tagaaggatg ttcattagct tatgacccta agaaaaaacg tgggtcactt atagtagatg
    38821 aagttaaaaa gaaagatata gatggtgtta tcttctgtat gatgaaattc tgtgacccag
    38881 aagaatacga ttatccttta gttagaaaag atatagaaga tagtggaata cctactttat
    38941 atgttgaaat cgaccaacaa actcagaata atgaacaagc cagaactcgt attcaaactt
    39001 ttgctgagat gatgagttta gcgtaagttc attaaaataa atttactata aaatatgaaa
    39061 attggaggaa gctatgttat ataacaaaga acaagaactt ttaagaaaag cagtaagaga
    39121 ttttgttagt aaagaattag atactttacc agcagaaatg gataaaacag gtgtaatgcc
    39181 taaggaatta atcaaaaaat tagctgatgc aaaatttata agcagtaata tcccagaaga
    39241 atatggtggt gggggagcag gatatgtttc ttacgctata gtaatggaag aaatagctag
    39301 aagatgtgct tcaacagcta cttttgttac agctggttct tctcttgctt cattaccaat
    39361 actttacaat ggtactgaag agcaaaaaca aaaatactta aaaggtatag caacaggtga
    39421 attaatagga gcatttggtt taactgagcc aggagctggt tctgatgcag gtggacaaca
    39481 aacaacagca gaattagttg gagaccacta tatattaaat ggtagaaaaa ctttcataac
    39541 taatggacca ttctgtgatg tagctatagt aatagcagtt acagatagaa gtaaaggact
    39601 tagaggaaca tcagcgttta tagtagaaag taaatgggat ggtttctcaa caggagctca
    39661 tgaagataag atgggtataa gaggaactga aacttctgac ttaatatttg aaaacgttaa
    39721 agttccaaaa gaaaacttac ttggaaaaga aggtcaagga tttaagatag caatgggtac
    39781 tctagaagtt ggtagaatag gtgttgctgc cttagctcta ggaatagctc aaggtgcttt
    39841 agatgaagct gttaaatata caaaacaaag agttcaattt ggtaagccta tagctaaatt
    39901 ccaaaatact caatttacta tagctgacat ggaaacaaaa gtttgtgcag ctagaggatt
    39961 agtttatgat gcagcacaaa agagagatgc aggaatgaga gttgctcaag aatctgctat
    40021 ggctaaatac tatgcatcag aaattgcaaa tgaagttgct tataaagcat tacaacttca
    40081 cggtggatat ggatttataa aagattatga aatcgaaaga atgtacagag atgctagaat
    40141 cgtatcaata tacgaaggaa catcagaagt tcaaaaaatg gtaatttcat caaacgtatt
    40201 aaaataataa ataatctaat gaaattggag gtatagactt tgaaaatatt agtttgcgta
    40261 aaacaagttc cagatactaa cgaagtaaga ataaataaag aaacaggtac tcttataaga
    40321 gatggagttc caagtatatt aaacccagat gatgcaaatg cattagagga agctttaaaa
    40381 attaaagatg agcatgatga tgtaactata acagttataa caatgggacc tcctcaagca
    40441 gactttatgc taagagagtg tttagctatg ggtgctgatg atgcaatatt attaagtgat
    40501 agagcatttg gaggagctga tacttgggct acatcaaata ctattgcagc gggaatatct
    40561 aaagtaggtg actatgacat aatatttgca ggaagacaag caatagatgg agatactgca
    40621 caagttggac cacaaattgc agagaaatta gacattcctc aagttacata tgtacaagat
    40681 ttcaaaatag aaggaaaaga tataatagtt caaagacaat tagaagatgg atacgaatta
    40741 ataaaagtaa gtacacctgt acttttaaca gcagtaaaag agttaaatac acctagatac
    40801 atgtctgttg ataaaatagt aaaagcatat aaacatgatg taaaagtttg gacaattgat
    40861 gatttagatg taaataaaga agaagttggt ttaaaagcat caccaactaa agtatttaga
    40921 tcatttactc ctgaaccaag aggaaaagga gaaatcttag aaggtaaagc tgatgaaata
    40981 gctagtaaaa taataatcgg tctaaaacaa aagcacatta tataagttgg aggagtacaa
    41041 actatgaatg atataaaaga tttaagttct tataaaaacg tatggatatt tgcagaacaa
    41101 agagaaggaa aaatagctcc agtagttata gaattattag gagaaggaag aaaattagct
    41161 aaagaagtag atgcagaact ttgtgcaata ttattaggaa aagatgttga tggattagct
    41221 aaagaattaa tcacttttgg agctgacaaa gtttatgttg cagatgatgc tcttttagaa
    41281 aaatatacaa ctgatgcata tacaaaagta ataaaagatg caatagatga aataaaacca
    41341 gaaataatgc ttttcggagc aactcatata ggtagagact tagcacctag aatagcttca
    41401 agagttggaa ctggattaac agctgactgt actaagttag aaatagaccc agaagataag
    41461 aaaataaaac aaactcgtcc agcatttggt ggaaacataa tggctacaat catttgtcca
    41521 aaccatagac ctcaaatgtc tacagttaga cctggtgtta tggataaagc tgaaaaagac
    41581 gaaacaagaa ctggtgaagt tatagcatta gactacaaaa taactcaaga tgatataaga
    41641 actactgttt tagaaacagt taaaactaag aaagatttag tatctcttac agatgcaaat
    41701 gttatagtat caggtggttt aggattaggt ggaccagaag gatttgaaat gcttaagaaa
    41761 ttagctgaca aattaggtgg agtagttggt tcttctcgtg cggctgttga tgctggatgg
    41821 atagaccatt ctcaccaagt aggtcaaaca ggaactactg ttaaaccaaa cctatatata
    41881 gcttgtggta tatcaggagc aatacaacat ttagcaggta tgcaatcatc agatttcata
    41941 attgctataa acaaaaaccc agcagctcca attttagaaa tcgctgacta tggagtagtt
    42001 ggagacttac atgaaatagt tccaatgctt atagaaaaat tagatagcgt tgatgattta
    42061 ttagaagcta taaaagctta atagatacaa actatataaa tattactgat tgaataagtc
    42121 ttattagtta gtaacataat tattaaccct ttgataagtt attgctagtg tgtatttgtc
    42181 agttattaaa aagtctgttt gaataaaatt ttataataca agataatctg gataatcctt
    42241 atatgtatat tgcttacaaa ttgtgagtta tattctgtaa ggattatctt tgttttttta
    42301 aataaatctt aaatttaatt aaattgtatt aaatagacaa ataattacta aatatgtgat
    42361 aaaatacaat taaaagcaaa atgaaatttt taacaaacta taatcattaa aattatatct
    42421 tagttacgtt ttaatgaaat aaactacttg aaaagacgaa tattataagg agttgattat
    42481 atgtgctgat ggtatttatt gtaagcaaac aataaatttt gtatgtagtt caataaatta
    42541 cttaatgaaa ggtgcgaata ttaatggata ataatttaat agggcttata gaacatgtag
    42601 aaaatccagc cattttatgt aaagaatcag gcgaaataat atactgtaat catctaatag
    42661 atagtatttt tagttttcta gatataaaaa agcctagaaa tataaatgaa ttagattcaa
    42721 attttgacaa aacagaaata ctgacagata gtaaaaagaa aatagctttc agagagttaa
    42781 ggatgactgc acatatatac aatatgaaag ataataataa tgaaaataat atagtttatt
    42841 tatttgagaa gtctctaata tctgataaag taattgaaga tataatagag catatagatg
    42901 aagttgttgt tgtgtttaac aaagatgggg taattgaaaa gatgaacact gtcagtgatg
    42961 agatattacc ttttaaaaga actgaggtac ttggtagaaa tataacagac cttgtgagac
    43021 aaggattagt tgaagaacca ataatattaa acatgcttaa agtgaagaaa aagatttata
    43081 gaaatatcgt ttacccagat gggaagctta ttgcatatac ggcagttcca agatgggatt
    43141 ctaagggaaa gcttacagga ggagtactaa cagggagaga tatttcaagg gttattaagc
    43201 ttgaatctca gataaaatat agtgatatat cagaagacac agagtatata agtcaaagta
    43261 agattatgga caatataaaa aaagttgtta agagagctgc agcctcagat tcttctatat
    43321 ttataaatgg agaatcaggt gtaggaaaag aaataatagc aagaacaata tataagtata
    43381 gttcaaggag agacaaacct tttatagcta taaactgtgg agctatacca aatgaattat
    43441 tagagtcaga gttttttgga tatgaagaag gttcttttac tggagctaag aaaaaaggta
    43501 aaaagggact ttttgaagag gcgaatggtg gaactatttt cttggatgag ataggtgagt
    43561 taccaatgca gatgcaaaaa aaattactta gggttataca agaaaatact attactagaa
    43621 taggtggtag taagcctata aaaatagatg ttagatatat aagtgctact aatatttctc
    43681 atgaagacct tagaaataac cttaaattta gacaagattt gtactataga ttaagtgtta
    43741 ttccagtaaa aatacctcct cttagagaaa gaaaagagga tatagtacca ttagtaaatt
    43801 atttcttaaa actttacaat gaaaagtaca atagagaagt agaagtttca cctaaagtta
    43861 ttgaattatt agaagaatat tcttggccag gaaacataag agaattaaaa aacatcattg
    43921 aaagatttgt agtattatca gctaaaaatg taattggaga agatgaattt aacatgctga
    43981 taaatttaga tatgattgat aatgaaacag atgatttatc accaatagtg gtaaatggaa
    44041 ttatgaatct taatgatgca tataaaatag tggaccaaat aatgataagt aaggctataa
    44101 ataagtatgg ttcaataaca aaggctgctg aagttatagg tatatatcct tctaccatac
    44161 atagaaagat aaagagtgga catattcacg tttagctgtc agtttaaaaa gacaatataa
    44221 ttaaaatatt ataagataca taattgatac aacttaaaag agatggctta aaaataaatt
    44281 taattacttt aagtcatctc ttttctttta taaatattta aaagttatat tagtttatag
    44341 agttaacaga acctaaaaca tcatctatct tgctttcaac tacagcttgt atagcatctc
    44401 taccagcacc aatgtatttt cttgggtcaa attcttttgg attttcagct aagaattttc
    44461 tgatagcagc agtcatagct agtcttaagt cagtatccat gtttatttta caaacagcca
    44521 tagaagatgc ttttcttaac atatctacag gtacaccttt agcaccagct atatttccac
    44581 caaattcatt acatgtagca acagcgtttt ggtcaacagc agatgcacca tgaagaacta
    44641 ttgggaaacc tggtaatttg ctttggattt cttctagtat atcgaatctt aatttagctt
    44701 ctcctttgaa tttgaaagca ccatgagaag ttccaatagc tattgctaat gaatcaacac
    44761 ctgttctttc aacgaactca actgcctcag ctggttgagt atacttgtga acatcagaag
    44821 taacatcatc ttctgttcca gctagaacac caagttctgc ttcaacaaca acacctttag
    44881 agtgtgcata ttcaacagct tctttagtta ttctaacatt ttcttcaaag tcaaaatgag
    44941 aaccatctat cataactgaa gagaaaccag catcaataca agttttaata gcatccatat
    45001 ttggaccatg gtctaagtga agagctacat ctacacctat ttcatcagaa gcagccttaa
    45061 ccatttcaac taatgtatga ggtccagcat atttaacagc tgacatagaa gcttgtatca
    45121 taacataaga atttttagct ttagcagctt ttaaaacacc ttgtaattgt tctaagtcac
    45181 ttatgttaaa tgcacctata gcaaatccac cttcgtaagc ttttttaaac atttcttttg
    45241 tagtaattaa tgccatttta aactcctcct attaactttt aaaatttacc catcacttat
    45301 attataacgt taaatcaaaa aaagtatata gtaaattgta ataactataa attacaagta
    45361 taatgttaaa tagaagacaa taggattaaa taaaataata aagaatataa acaatttagg
    45421 aaaattagct atataatgct aactataagg gtaggaacta ccttattagt ttggagatac
    45481 tgataacaat agttgtcttg accaagaagt tgccacttca aacgttatcg aagggaatta
    45541 agtggatgat aattcactaa aaatttaaaa taaaggagat agaatatgcc acagataaaa
    45601 ataagaggaa ttaatgaaaa tgatatatgt aaaataagtg aaaaaatgat aaatgattta
    45661 gttgaagctg taaaatgtcc aagagactac tttgaaatag aatgtataaa gtcagttgca
    45721 ataagagatg gtaaaatagc agatgtatat ccttttgttg aagtagcttg gtttgataga
    45781 ggacaagaag tacaagatat agtagcaaga ataataactg atagtataag aaataattta
    45841 gatgtagaaa gtatggattt agcatttaca gtatttgaaa aagaaaaata ttatgagaat
    45901 ggagagcatt tttaatggct aaaaagcaac gtatagataa aattctttca aatttaggtt
    45961 atggaagcag aagtgaaata aagaagtatt gtaaacaagg gtctgtagta gtaaatggaa
    46021 gtgaagtttc aaatccagga actcaagtag acactgaaaa tgatgagata ttatttaatg
    46081 gagaagaagt tatatataga gaatatatat atttgatgat gaataaacct gatggatata
    46141 tatcagcaac tacagataaa tatgacccaa cagtattaga tttaattgat ttatcatact
    46201 tagcttttga accatttcct gttggaagat tagataaaga cacagaggga ttattagttt
    46261 taactaatga tggaaagctt tctcatagag ttttatctcc taagaagcat gtgcctaaga
    46321 cttattatgc aaaaattgat ggagtagtta ctgaagaaga tgtagaagct tttttagaag
    46381 gtgtagtgct tgatgacgga tataaaacta tgccatcaca gttaaatata ttaaaaagtg
    46441 atgatgaatc agaaatagag cttacaatac atgaaggtaa gtttcaccaa gtaaaaagaa
    46501 tgtttgaaag cgtaggcaaa aaagtagtat acttaaaaag attgtctatg ggcaatttaa
    46561 aattggatga aagtttagag ttaggtgagt atagagagtt aacagatgaa gaagtaaaat
    46621 tgattgaaga aagataataa agatactata gtaaattgga ggaatgtctg tgaagaaaaa
    46681 agatgttata gaatttgaag tagataaaat ggaatttggt ggtacatctt taagccaagt
    46741 tggagataga gttatccata tgaagggtgg aataagtggt caaaaggtga gagctggagt
    46801 taaaaaagtt agaagtaaga aagctgaagt taagatgata gaattattag agaactcacc
    46861 gcttgaaact gaagaaactt gcaagcactt tagagagtgt ggaggatgta cactattgtc
    46921 tgtgccatat gaaaaacaat tagaaataaa agaaaaacaa gttatggatt tatttttaaa
    46981 gcaagattta tttggatttc agtttttagg gatagaagga agtccagaaa acaaatatta
    47041 tagaaataag atggaatata cttttggaga tgaagtaaaa aatggacctt tgacattagg
    47101 tcttcataaa aaaggaaagc atatagatat acaaactgtt gaggagtgta tgttggttga
    47161 tgaagacttc tcaaagatat tagtttctag tgtagagttt ttcaatgaaa aaaagcttcc
    47221 ttattataga acaatgaatc acaaaggata tttgagacat cttgtagtta gaaaagggat
    47281 tcatactaat gagattatgg ttaatatagt aacttcttct caagaagatt ttgatatgta
    47341 tgagtttaaa gatatgcttt tagggattga tttaaaagct gagttagtag gtgtacttca
    47401 tactattaat gatggtttag cagatgcagt ccaatgtgat gagttaagag tattgtatgg
    47461 aagagattat atacaagaag aaattttagg tcttaagttt aagatttcac cattttcgtt
    47521 tttccaaacc aatactaagg gagctgaggt tctttatagt attgctaggg attttattgg
    47581 agattacaat gataaagttg tatttgactt gtatagtggt actgggtcta ttggacaggt
    47641 tatggctggt gctgctaaga aagtgtatgg tattgagata gttgaggaag ctgttgttgc
    47701 tgctaatgag aatgctaagt tgaatggact tactaattgt gagtttattg ctggggatgt
    47761 ggctaaggtt gttaaggatt taaaggacaa gcctgatttg attattgttg accctcctag
    47821 accaggcatt cataaggatg ctattaggga tatttgtgga tttggtgcta aggagattgt
    47881 ttatatttct tgtaatccta agtctttggt tgttgatttg gttgatttta aggggtatgg
    47941 ttatgagatt aagatggtta agtgtatgga tatgttccca aatacgccac attgtgagac
    48001 tgtagttaaa cttattagag aataacaggg tttcagactt ttatagtgtg tcttaaaagt
    48061 agatttgcta ccataattat ttttgggtgg caaatttatt ctacaatgat ttcaaaaata
    48121 tttaccgtct ggtttctcat gttattagtt acatgtaaat atgtatccat agttgttgaa
    48181 gttttagcat gtccgagtat atgctggata tcttttatat tagtaccatt ttctaataac
    48241 atagtatcag ggtttttaaa ataaagtgtg tattcttcta aagtagtgat aattaaaata
    48301 tcaaatatca ctatacaaag gaaagtgcac gctttttatg tttaacaaaa acgaaatatt
    48361 aaaaaactta ttgaagaata tgatgtcaaa acaactacag atattcaaga tatgctaaaa
    48421 gatttattta caaatacaat tcatcaaata tttacattgt cgaattttaa cggtttaaac
    48481 ataatatatt gactgatata ataaaatcat agaatatttt agggggaaat agattatgtt
    48541 taagaaaaag ttaatagctg ttgcaatgag tataactatg attagtgtag ggagcttttc
    48601 gtatgctcat tcaggaagaa ctgattcatc aggaggtcat cgtgataata aaaataaatc
    48661 tggattagga agttatcact atcattgtgg tggttatcca gctcatttac ataataatgg
    48721 tggttgtcct tatactggag gaggaagcag ttctggaaca acaacttcgg ttaataatga
    48781 agaaaagcaa aagaggtctg ttggagaaaa aggatataat caagggtatg aagatggata
    48841 taaaggaaat tatagttcat caaattatag tggagattat agtgatacat atgaatcaaa
    48901 gtactcagaa ggatatgaaa aaggtaaggc taaattagaa gaggaagaaa aggtggctaa
    48961 agagactgga tataatttag ggcttacagg tgctaaatct aataatacat atgaaaaaga
    49021 agttttaaaa aatgcttatg ataccggata ttcaaccgga tacaatgaat ataagactaa
    49081 aaagatagaa gaatataaag ctaaagggat agaggatagc aataaagata aagaaaaaat
    49141 gacatttgaa gaaaacatag attctgaatt tatagatgct tataataatg cttatgacga
    49201 aatacaagaa caattaaaaa atgattacac tactcaagga tttgagagtg ctatcaaagg
    49261 agaaagattt gacacatcaa ctataggtaa tgttaaatat gctaattggt ttaaagaagg
    49321 atatgataat ggtaaggtta agttacctaa agcaaaagaa agtgtatata atcaaggtta
    49381 caatgaagaa gattttagta taccagatga aatgaagtct attgaaacta agttaaaagg
    49441 tgtatatgat gaaggtttag aaaaaagaga ggaagagaaa agtagaaatg ctacttatgg
    49501 ggttggagct ggaacagcag ctgtagttgc tggagtagta tataaaaaga aaaaacgtaa
    49561 aaagatatag atactagata taccaatgat gacaagtgta taacaaatat aattttaagt
    49621 ataaatattt aaaatataga agggaaggtt atatctatgg gatttaactt taggaaaagc
    49681 ataaatctag gaggaggact caaattaaat ttaggtaaga agagtgtagg tataagtgct
    49741 ggtgttaaag gtgctagagt gtcagttaat tcaaaaggaa gaaaatcagc tacattgagt
    49801 atacctggaa ctggaatatc atatacaaaa actagtacaa agaaacgtaa acctaaataa
    49861 atatttgata tactaagaaa tagactgtta caaatagtct atttcttagt atatagattt
    49921 aaaaagtgac aaaattttga aatataaact aatttcataa aggaaaatat tcttttatgt
    49981 agaattataa tatttaagta atattataaa atttatagga ggatttcatt atgaaattaa
    50041 acaaaacact attggcaata gggatgtctg tttcattatt gattgctagt tgtccaacat
    50101 caaacgctct taattctatt aattcaataa aaggtacaaa taagtatgaa acagcaggtt
    50161 taatagcaga taaacaaaat tatgatattg caatacttat taattctgaa aatggattat
    50221 ctgatggatt gtcagcaagt ggattgtcag gagctaaaaa tgccccaata ttgttaacta
    50281 agaaagatac aatcccttca gaaacattaa aaagattaga aaaggtaaaa gaagtatatc
    50341 taatcggagg aaaaaattcg ataggagcat cagttcagaa aatattaagt gataaaaaaa
    50401 taagcataaa tagaataagt ggaactgata gaatagatac aagtcataaa gttgcaaaag
    50461 aaataggaag tgtaagtgct gttaaaaaag taatattaac taatgctttt aaaggtgaac
    50521 cagatgctat gagtgttgct tctatagcag ttagagataa atctccaata gtattaactg
    50581 atggaaacac tacaagtttt gctacagatg gattagaaac ttatgcaatt ggtggaaaag
    50641 tcagtattag tgataagtta ataaatgaaa ctaaagcaac aagaataggt ggagtagata
    50701 gatacgatac aaataaacaa ataataaata aattttataa tggctcaaaa gaattttaca
    50761 tagcaagtgg gactgattta gtttattctt tagttggttc tacaattgca caaaaaacac
    50821 ctatagtgtt agttggaaat ggaagtaata agagtatatt aaaaaatgca agtaaaataa
    50881 ctgctattgg aaatattgat gatgttgtta taaaacaatg tttaaatata actaataatg
    50941 ttggggattc aaatacaggc attgtaaaag atactaattc aaataatacg aacaaaccaa
    51001 gtaatgagcc tagctctaat aatcctggat taactgataa aagtacagta tatgtaactc
    51061 ctaatggaaa atcatatcat ctaacaaaaa attgttctac actaaaaaga agtaaaacaa
    51121 taaataaagt aacattaaaa caagctaagt cacaaggtaa aatagaccct tgtaatgttt
    51181 gtgtaaaata atgtattagc caaatatata ttaaaaaaga caattaatta agattgtctt
    51241 ttttattgaa gaaatataaa tttatattat gtattattaa aaaaaaatta ttaattataa
    51301 aaaataataa taaagacgat aagtattaaa attttatgtt tccaatattt atgatataat
    51361 taatatggca aggaataaat atttgaaaaa gctatgagtg gtgtttccat ggaagtttct
    51421 tcactttctt atgagaggag gtgaaaacta tggaaaatct aatgatgagt attataactg
    51481 gtgttatagc cagttacatt tacgataaat taaagagcca ctctgagcga ccaactaaga
    51541 gtggctggga acttaatata aagttccaga aaagtaaatc ttcaaaataa tttgttgaag
    51601 gaaacatcac tcaaagttaa gtaaaatatg tttccttgct tttattatat cacaaattaa
    51661 aaatattaac acaaaatttt gtgaatatat acttattatt gttctaaaaa aatatgtaaa
    51721 taattgattt gatttcatag aattattgtt gtaatgttta gttaaatata cacaatctca
    51781 attaaagaag ataagtacta taaattcata tcaaaaaaat acataaactt ttaagttata
    51841 attttataaa aagtctttta gtatcattat ttcaagagga attaacatat gaaaaaataa
    51901 cttcattaga aaagtggata aaaaactggt aagaagatg
//
LOCUS       DAEQAF010000015        50568 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.015, whole genome shotgun sequence.
ACCESSION   DAEQAF010000015 DAEQAF010000000
VERSION     DAEQAF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 50568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50568
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.015"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(129..908)
                     /gene="hisJ"
                     /locus_tag="KRN00_001029"
     CDS             complement(129..908)
                     /gene="hisJ"
                     /locus_tag="KRN00_001029"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBH1826897.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGKELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNTILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLELVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(1454..1804)
                     /locus_tag="KRN00_001030"
     CDS             complement(1454..1804)
                     /locus_tag="KRN00_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBH1826898.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(1820..2236)
                     /locus_tag="KRN00_001031"
     CDS             complement(1820..2236)
                     /locus_tag="KRN00_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBH1826899.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(2255..2446)
                     /locus_tag="KRN00_001032"
     CDS             complement(2255..2446)
                     /locus_tag="KRN00_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBH1826900.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(2597..3412)
                     /locus_tag="KRN00_001033"
     CDS             complement(2597..3412)
                     /locus_tag="KRN00_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBH1826901.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(3459..4397)
                     /locus_tag="KRN00_001034"
     CDS             complement(3459..4397)
                     /locus_tag="KRN00_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1826902.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVTISLFAFTPVRGTKMEKIS
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(4394..5266)
                     /locus_tag="KRN00_001035"
     CDS             complement(4394..5266)
                     /locus_tag="KRN00_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1826903.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(5291..7219)
                     /locus_tag="KRN00_001036"
     CDS             complement(5291..7219)
                     /locus_tag="KRN00_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBH1826904.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(7331..7708)
                     /gene="gcvH"
                     /locus_tag="KRN00_001037"
     CDS             complement(7331..7708)
                     /gene="gcvH"
                     /locus_tag="KRN00_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBH1826905.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(7795..9921)
                     /gene="cdhC"
                     /locus_tag="KRN00_001038"
     CDS             complement(7795..9921)
                     /gene="cdhC"
                     /locus_tag="KRN00_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBH1826906.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(9978..10784)
                     /locus_tag="KRN00_001039"
     CDS             complement(9978..10784)
                     /locus_tag="KRN00_001039"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH1826907.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(10834..12201)
                     /locus_tag="KRN00_001040"
     CDS             complement(10834..12201)
                     /locus_tag="KRN00_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBH1826908.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(12232..13176)
                     /locus_tag="KRN00_001041"
     CDS             complement(12232..13176)
                     /locus_tag="KRN00_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBH1826909.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(13196..13966)
                     /locus_tag="KRN00_001042"
     CDS             complement(13196..13966)
                     /locus_tag="KRN00_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1826910.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(14022..15407)
                     /gene="lpdA"
                     /locus_tag="KRN00_001043"
     CDS             complement(14022..15407)
                     /gene="lpdA"
                     /locus_tag="KRN00_001043"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH1826911.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTVKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(15451..16332)
                     /locus_tag="KRN00_001044"
     CDS             complement(15451..16332)
                     /locus_tag="KRN00_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBH1826912.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(16368..17042)
                     /locus_tag="KRN00_001045"
     CDS             complement(16368..17042)
                     /locus_tag="KRN00_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBH1826913.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(17079..17951)
                     /locus_tag="KRN00_001046"
     CDS             complement(17079..17951)
                     /locus_tag="KRN00_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBH1826914.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLVKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(18043..18675)
                     /locus_tag="KRN00_001047"
     CDS             complement(18043..18675)
                     /locus_tag="KRN00_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBH1826915.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVDKVKTEVDKLVEEGVKTCDEVYAKVEKALGK"
     gene            complement(18780..20456)
                     /locus_tag="KRN00_001048"
     CDS             complement(18780..20456)
                     /locus_tag="KRN00_001048"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBH1826916.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(20705..21484)
                     /locus_tag="KRN00_001049"
     CDS             complement(20705..21484)
                     /locus_tag="KRN00_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1826917.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(21794..23713)
                     /gene="cooS"
                     /locus_tag="KRN00_001050"
     CDS             complement(21794..23713)
                     /gene="cooS"
                     /locus_tag="KRN00_001050"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBH1826918.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKAGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(24320..25231)
                     /locus_tag="KRN00_001051"
     CDS             complement(24320..25231)
                     /locus_tag="KRN00_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH1826919.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(25347..25481)
                     /locus_tag="KRN00_001052"
                     /pseudo
     CDS             complement(25347..25481)
                     /locus_tag="KRN00_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
     gene            complement(25564..26706)
                     /locus_tag="KRN00_001053"
     CDS             complement(25564..26706)
                     /locus_tag="KRN00_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1826920.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKGIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELGINK"
     gene            complement(26724..28478)
                     /locus_tag="KRN00_001054"
     CDS             complement(26724..28478)
                     /locus_tag="KRN00_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBH1826921.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            28614..28820
                     /locus_tag="KRN00_001055"
     CDS             28614..28820
                     /locus_tag="KRN00_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826922.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(28825..29748)
                     /locus_tag="KRN00_001056"
     CDS             complement(28825..29748)
                     /locus_tag="KRN00_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826923.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(30002..31702)
                     /locus_tag="KRN00_001057"
     CDS             complement(30002..31702)
                     /locus_tag="KRN00_001057"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBH1826924.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(31961..32374)
                     /locus_tag="KRN00_001058"
     CDS             complement(31961..32374)
                     /locus_tag="KRN00_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBH1826925.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(32442..34820)
                     /locus_tag="KRN00_001059"
     CDS             complement(32442..34820)
                     /locus_tag="KRN00_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH1826926.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKSGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            35139..36590
                     /locus_tag="KRN00_001060"
     CDS             35139..36590
                     /locus_tag="KRN00_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBH1826927.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKKVEGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(36794..39307)
                     /locus_tag="KRN00_001061"
     CDS             complement(36794..39307)
                     /locus_tag="KRN00_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1826928.1"
                     /translation="MEDCVVNLKKLLLLIIVITSIFTSCIFSFGINAIGNDNRTIRVA
                     YPIQKGLTEIDEQGNYFGYTYEYLLEIAQYTGWNYEFVQVPGEINESITKLMKMLENG
                     EIDIMGGMLYNEPMQKIYNYAGNSYGVANTVLQALYENTDIDNIMSSQSVKKIRIAVI
                     ENSDTRFKELDEYCKMNLMSPELVYCKTSDEQLEALKSGKADVLLNVSMNPIEGVRTV
                     AKFSSKPFYFITPKGSTDLTQKLNSAINNIEQKDPYFSTTLYEKYFTPENNQMFLSDE
                     ETNYIKDTEKLKVGVLLNKPPFQNADKDTGELRGISIDLLNHICDKTGLEFELVPVKS
                     QEDLEDMAKKHEIDIIAGMIYDYEYSREHNIAMSRPFISTQYTMMINNKLNENSLDGK
                     CIALTKGINYDGQFEENIVWYDNLEECIEAVNKGYADYTYGEGYSMQYYMNQPKYKNV
                     RLVPQTYKAKSICFGIIKKDKQELLNIFNKAIISISSEKMQSIVYQNTTYRQDFSLLY
                     IMQQNPIETIFIVASLLICIIGFMAFGLHTRTSMNEKISLELKKHTQLYEMTSEYFFE
                     YDYKQDKLIISMPEKGIETYYGLDKNDKESENGNIENERDKIRREYNKKFFDVIKSQE
                     NGTTEMYSIMLDDTFHWIRVTSKIIYNDRKIPMYVIGKICNIDSEKEEKNRLLDKAQR
                     DSLTNIYNAAYIRKLTAQNLLNLSTEKNGALLIIDIDYFKSINDTYGHLVGDKVLIDV
                     AKALDESFVKNDIVGRLGGDEFSVYINDIINKEELINKCNDVYNHIHLIKLPNGESLS
                     ISMGVVIAKPGQEYDELYQIADNALYDSKRQGRNRFKIV"
     gene            complement(39530..40351)
                     /locus_tag="KRN00_001062"
     CDS             complement(39530..40351)
                     /locus_tag="KRN00_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1826929.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(40869..41345)
                     /locus_tag="KRN00_001063"
     CDS             complement(40869..41345)
                     /locus_tag="KRN00_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBH1826930.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(41379..41957)
                     /locus_tag="KRN00_001064"
     CDS             complement(41379..41957)
                     /locus_tag="KRN00_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH1826931.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(42061..44661)
                     /locus_tag="KRN00_001065"
     CDS             complement(42061..44661)
                     /locus_tag="KRN00_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBH1826932.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFNRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSLKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPSRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLGTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHYNTAVTDKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
     gene            complement(45113..45796)
                     /locus_tag="KRN00_001066"
     CDS             complement(45113..45796)
                     /locus_tag="KRN00_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBH1826933.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(46111..46701)
                     /gene="zapA"
                     /locus_tag="KRN00_001067"
     CDS             complement(46111..46701)
                     /gene="zapA"
                     /locus_tag="KRN00_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBH1826934.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(46726..49119)
                     /locus_tag="KRN00_001068"
     CDS             complement(46726..49119)
                     /locus_tag="KRN00_001068"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBH1826935.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(49136..50155)
                     /gene="pheS"
                     /locus_tag="KRN00_001069"
     CDS             complement(49136..50155)
                     /gene="pheS"
                     /locus_tag="KRN00_001069"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBH1826936.1"
                     /translation="MQEKLLALREAALAEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(50205..50439)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT        15240 a         9884 c         5588 g        19856 t
ORIGIN      
        1 tattttactt agaacttatt attattttat ttaagttcta ttactatttt caatcatata
       61 aatttactaa agactgtaca taaatttatt ttatacaaac ttatctacag tcttttgtgt
      121 gaatatatct aaataatatc gtatttattt atttcctctg cacagtgaga atcagaacct
      181 aaaactaatg gaatatcgta tttttttacc aactctaata agtatccatc tatataaggc
      241 tctttgcagt actcttttct atttccagaa acattataat caagttcata acctttttct
      301 ttaattaact ttattaactc ttcaagaatt gtatttcctt tataatcgta tggaaatacc
      361 tgattaaact ttctaactaa atttaaatga cctattcttt ttggtttatg tatacctaaa
      421 tctgaattta cagcttttat caatgtttca taatacttat tataaacagc ttcaatactt
      481 cctaatttgt cgattaaatt ttgaaactcc tctacactgt aatctacaca ataataatca
      541 tcatcaatct taattatatg tactgataaa agagaatcct ctaattcctt tccatattta
      601 tttaaattct cctttattcc ttcttcgtat ccttctataa aatccacttc cgacccaaca
      661 tttatcttga ttttaccctc atacttttct ttcaacttct tgacatcatt aaaatacttt
      721 ggtaaatctt caatactcat acaactatca ttttcaggag cagggtctct aaatccattt
      781 gcatacggaa aatgttctgt aaatgtcatt tctgttattc caacatccat tgctctttgt
      841 acatattttt caaaatcatc cttacttcca tgaggacaat aaggtgaatg tatatgacca
      901 tctttcataa ataattcact ccttttttaa agaaaaaatc taatataaat gcataaatct
      961 tttaacttca aaataatatt tttaatcatg ctaattttta ttatatctaa tattagagta
     1021 attttaaact gccttttaag tatcttatca ttagtactat tttcaactta acattaatat
     1081 tattttttaa cttaacatta atactatctt taaatagtaa tactcaatat ataattactt
     1141 aacataaaat aactcaaatt gcttgatgag gcttttgcag tatttaaaga atatataatt
     1201 atttaacatt aaataatcca atcttgtaat aaaatttact cattaaagta tattacagaa
     1261 aatacctcaa aataaacttt ttagttcatg atatactctt ttttgcatga aattagatat
     1321 atttttatca tttcaacaat gaaagggagg cttatatcta tctttagaca accccttaga
     1381 taaaattttt aataattaaa catcacaaaa tataaaaatc gcttatatca aacgtataag
     1441 cgattaatta tatttacata tgttttttag cctctaacaa cattttatta gcttcttcca
     1501 tatactctat agccttttca atactctttg ctgtttcttc ttttccaata gctctagcct
     1561 tttcaaccca ctctctaaat ccttcttcat gagtttcatt gtgatttatc caatgtacta
     1621 aaagtatttt taaagttttt tcatccttag actctgatga ttcctcatga ctatgttcgt
     1681 ggtcgtggtc gtgagcatgg tcatgtggat gttcatgaca tatatctcca tgagtatgtt
     1741 cgtggcagtg gtcatggtca tgatgtccat gatgatatct tacaatctct ttatcaaaaa
     1801 tcattagtta ttccccctgt tattttatat taaactcttt ttttataagg tttacagaat
     1861 cttttacaag tagtgctaat ggtttacctt ctaatccaac taactccaca ttttctggca
     1921 taataggtaa aagtatctta agtgcctcac tgtctgcaat agcttcactt atattacaag
     1981 taacttctcc catcatagaa ttaggtatta ttacagaaat aggtgcaact attatatttg
     2041 cttttttagc tgatactact atagcatttt cccctgtagc tcctttatta gcatgagctt
     2101 tcatcataga actagttgct atagaattag tccctagtgc ataaatttct acatatgtag
     2161 gtaactcttc tctcaaagaa gaaactatct gggctccaat acctccaccc attccatcta
     2221 tcactgctat tatcatatga aattccccta ttaattaatt ttcttgtatt attatcttat
     2281 ggtccatcaa tcttatttct ttaattatcc catctattat cttttgctct cctaataaat
     2341 ccgttaaata aatctttcca tcacaagggt ctatattaac cacattttcc ataacctttt
     2401 ctaactcatt attactttta caaatgaaag ctgatgattc acacatataa atctcctcct
     2461 aatatgattt ttattaaaaa tcaaaaaaag attcccttag gtatttcaat acaccaaaga
     2521 aaccttcatg atttcagttt ttgtatatta ttatacctta agtatatcac tttaatttat
     2581 gtaaagtcaa ttaaagttaa cgctttttat tatactcttc attcttgtat ttttcatata
     2641 gttctttaac taattgcttc tcataatcag tcaaatcgcc ctccacaaac tcaacattaa
     2701 attgttcagc taatcccttt actatgtttt tctgtagaat atctatgtct atttttctgc
     2761 caatttcatt ttctattcca cttgcttttt tagctgtaaa tttcatagct ctttctttca
     2821 attctggtgt cttagttttt attaatttaa acaatttttc tacatcaaaa tccagtatta
     2881 ttgaaccatg ttgtaataaa acaccatctt ttctgctttg agcacttcca attaccttct
     2941 tattattaat agtaacttca tatgatgcat gtgcattaaa acatgcagct gataaatttt
     3001 ccctacttat tctctcgcct ctatttaaat tatctgtttc tataccactt aaattcaatc
     3061 ctttaactag accttcactt atatatctat aagataggtt gatgctctta tcgattaaag
     3121 gattatcttc tcctataatt atactatagg ttagctcatt atcatgtaat acagctcttc
     3181 cacctgtaat tcttctagta tagtctatat tcatacatct acacttatct aaatctatct
     3241 catcttccaa tttctgaaaa tatcctatac tcaaacaagc tggttcccat gtataaaatc
     3301 taagagttgg cttattatgt cccttcttat atgcagtaaa tatagcttcg tcaattgcca
     3361 tattcattgc tccttcatat gatttattat gtataactct ccactgattc atgattatta
     3421 cgcccccatt tttagtataa atatatccta gaaatcctct atagatttat ttctcttatt
     3481 gctaaatcta tctcactttg atttaaaggt cttgaatagt tgtatatagt acttcctggt
     3541 ctttcattat agtatggtct attacaatcc ttacaacctc ttatttcaaa aggatagcct
     3601 ttgtttatgt cttttaaaat atcattgtca agctttatac tatttaagta tccattttta
     3661 aacttaaaat actcttttgg ataaccttta tttatcatat aagacattaa ctgtaccctt
     3721 ctataacttt ctatgcttgg ttgacttatc ttttccattt tagttcctct aactggagta
     3781 aatgcaaata aactaatcgt tacatcattt tcctttaaat aagtatataa attgtatata
     3841 tcttcatgac tttcacccat accaactatt atatgtgtac ttattttatt gggatatgat
     3901 tttgacattt cagttataaa ttttaacttt tcatcatagt tatttccttt tattttttca
     3961 tatagttctt tatttgctgc atctattgct attcctattt tatcaactcc tactgaaaaa
     4021 aacttcttta tctgttcatc attttctaat tttgcagata gtgaaattgg catgtctatc
     4081 ttaccactta tatagtttat aaagtctaaa acagagttat gtgcttcttc acttgccatt
     4141 gattgaatac atattctctt tatatttttt cctttataag cttttaaagc atctaatatt
     4201 tcttcttttg aaaactctgg ccaaattact cttgataatt tatcttttct agtactactt
     4261 tctattgatt gagaacaaaa actgcattta tttatgcatt tttctccaat cattatatat
     4321 gctgtggtag gaggtatatc gctttttttg tttaatatcc caagttctat tgctgtccca
     4381 actgatagtc taatcataaa acgcaacact ccttacactc atttattgtc atattcattt
     4441 ctatagcctt attctttgca gaccttgatg gtaatactat tctattgact ccacacatta
     4501 tagataattg gtctagctct tttctataca ctcctcttgg tctcatacaa cctagattaa
     4561 tttcagtatc tggtaaatta attctagctt cacataaaat atctgctacc ccttctaact
     4621 caggaggttc tacattttca tactcagtcc cttttgttgg aataaggact ataaatgtaa
     4681 gcttattagg aggatttttt tgtaggtatt ctataatttc atattcaccc tttatttgtc
     4741 ctccttttaa accaatacat atatgtggtg ctacttctgt atgttcttgt attgtattat
     4801 agacttcaat ataatcttct ttactctttt tcatcttata aacttctctt attgtctcat
     4861 catcaaacac taaatcaaaa gaaactatat ctaaatactt acacaactct acaatgctat
     4921 ctttatccat aagacctaaa tgagcattca atctatatcc ttgctctttt aagtttttaa
     4981 tggtattaat atgagtattt atagggacat ctccctcata actacaaccg ccactcaata
     5041 gaaagctagt tatattcctt gattgtactt tttcctcata ttcttctatt ggcaccatat
     5101 tgtttaagta gtgaccgttg caatgggcac atttcaaact acattgattg cttgtagtac
     5161 taagagctag tgtctggtta ggataagcaa actctatttt atttccaaaa ttctttaatt
     5221 taatatcaaa tgctattttc attttttcag atagattctt attcatagtt tattccttct
     5281 taagtacatt ttactcttct agtaatttct ttgctgttgg gaactgctct atattcgtat
     5341 gtggtaagaa acatgcagaa ataaattcat ccatataact tggatataca ctaagttcaa
     5401 cataagttat ttgattacct atttcttcaa gtttattttt tgcatcttta cttatgagag
     5461 ctaagtaaga accaacaagt gaactattcc ctatataagt aaatttttct ctatcgatat
     5521 caggaagtaa ccctataatt attgagtttt ctatgtctag gttgtttcct ataccacctg
     5581 ctatataaac cctatctaat atactaaaat ccatacctaa actatctaca agagtgtatg
     5641 cgcctgaata tatagctcct ttagctctga tgaaattatc tatatcaact tcattgacta
     5701 ctatatcatt ttctaaatca aattcttctt taaatgctaa tacatactct cctatctcat
     5761 gctcattaaa tctaactctc ttattatcta aatccctgta tattttacct cttctatcta
     5821 ttacaccttt agtaatcatt tgacagatta aatcaattat accagaacca catataccaa
     5881 ctggtgcaca ttcatcaata atctttaatg ttggctctaa agtatcttta tcaataatta
     5941 ctttctctat tgctcctgct gatgctctca ttccacagct tatccctcca ccttcaaaag
     6001 caggtcctgc tgaacatgca caactcatca tataatcttt atttccaaat acaatctctc
     6061 cattagttcc taaatctata aataaaacat tttcttcact tgaccatatc cctgctgata
     6121 atacacctgc tgttatatct cctcctacat aacttgcaac agatggagct aagtacacat
     6181 atgcactgtc atttacaaaa agaccaacat tttcacccat aagttttgga gattttaaaa
     6241 atggtggtat gtaaggttct tgtcttaaga agtctgtata cacacccaag aataaacttg
     6301 tcatagttgt attcccggca gccactaatg taactacatc ttccttatct attccatttc
     6361 tttcatatat tgtttttaat agtggattta tagtttcctc aactatagct ttatgaagtg
     6421 tctctaatcc atttttctta gttgaatata taattctatt tataacatct gctccatatt
     6481 ttatctgtgc atttccagaa gatgctttat ctactacctc ttttgagtat aggtctacta
     6541 aacaaacaac tactgaagtt gtaccaatat ctattgcaac tccgtataag gaattttctt
     6601 tatttccttg ttctatattt atgattgtaa gtttcttttg tttttgaaca tatgttattg
     6661 taaccttaaa atcactcttt ctaaatacag ttggcatttt tctaagtata tccaatctaa
     6721 aatctatttc attatatcct aggttatttc taacatatct ttccaatcta tctacatcac
     6781 ttatattatc atctaaattt ggttcttcca tttctatgta tttctttttt atatttgttt
     6841 taaattgaag gttatgttct tcaattattt ttttagctct ttcaaaaatt tccctatcct
     6901 cttttttatt actaccttct atcttcatac catgcataga ggatgatact ttagaaggaa
     6961 cttcaatttc tatatctgat attacctttg tacaacaagc tagtatataa ccttgctccc
     7021 actcatcatc tgttatatgt cttgtttttt ctgtatcaac ttttccattc aataatttta
     7081 ctttacactt cccacaagac acgtttccat tacaaggagc atctatgaat atatctgcat
     7141 ttcttgcaac ctctagtaat atatccccct cattacaata aacctcttta ttgtttggtg
     7201 taaaacttac ttttatcatg ttatccctcc caatttgttc tatatatgat aaaaggaaag
     7261 tatagctaaa tttgcgtgca ctcaaatttt actatacttt ccccaattat aataatatct
     7321 taatctttaa ttattctaat ccagcctcgt attctttatc acttaataac gtatcaagtt
     7381 cagccacatc agctagtttt acttttaata tccagttttc atatgggtct tcatttatac
     7441 attctggctc atcttctaat ttttcattaa cttccaatac ctcaccatta acaggagata
     7501 ttaaatcaga agctacttta gaagactcaa ctactccaaa atctactccc ttagttacag
     7561 tatcttctac ttctggtgtt tcaacaaaca atatttctcc taattgatct tgagcatagt
     7621 ctgttatacc tatatataca acatctccat caattacttt tacccactca tgatctttag
     7681 agtattttaa ttctggtaat aatttcattt cgatagaccc ccaatattat attattgatt
     7741 aaattactta aatcatatta atattatatc atattatttt aaattttcca tcaattacat
     7801 tacactttcc atagctaatg ctggatgacc tttttcttct aagaaagcta atactccttc
     7861 agaatcgtca gctatagttt catcacaaac catatcacag aagttttcta ttccagtcat
     7921 ttctttaact gtagcattta atttatcagc tacataatct tttaattctt ttggcatcca
     7981 aactattctt tctggtccac cttctgcata agcgaatttt ttagaagata tgaaatgtct
     8041 tccgtgtccc ataaatcctg gagtttgaac tcctccacct gtcatagaag caagttctcc
     8101 gaaagtcata ccaactggag taacacttgc aaattctctg ttaactacaa caaatccatt
     8161 tgcttctggc attataccac agatacattc gaagcatcca caagaagtca ttgggtcttc
     8221 tagtatagaa tataatgtaa cagattcaac tgcaccttga gatatttggt ttacagtttc
     8281 atttactgaa ttccatacac ctgttctatc atctaagcac tcgccttttt ctattggttg
     8341 acaaggacct gttgggtcta gttctttagt agccttagca tctaaccagc taactgctcc
     8401 acaaagacca agtctttcag gagtaacaac acaaacgtga gctggtgcaa atgattgaca
     8461 taagttacaa gaatagaaag tatcaacact ttcatcaact aatgaagcta atctttcatc
     8521 tctagcattg tacttagcta ttgcttctcc ttttaattca gaaacttttt cagcatctgt
     8581 aattatagtt atttcacact tatcaactac tgattcaaat tcatctagca tcttagcata
     8641 taaaacttct cctatatgct caagtctaaa tcctttatca aatgcatctt tagagattct
     8701 tacccaagcc atatctcttt gtccaacgtg cattacacct tctatatagt ttaagaagta
     8761 gtggaaacgt ctttcaagaa ctggctcaaa atcttcttgc atatttttac cagctatttt
     8821 aactattaca gcaagtggta atcttaatac accatctgca tcaacttcat ctatatttgg
     8881 tcctattatt tctatcttat ggtcttcaac ttctgttgct tctttcttaa caacaagctc
     8941 ccaagcttca gttctgtttc caccaaactc agcaaacata tcgctctttc taattctctc
     9001 accttcaaat gctgctgcaa atgaaactgg gataggtatt tcagtaactt ttatttttat
     9061 tcctctagct tctaatgaag tagctactat cttatcgtaa tctttttgag ttaataggtt
     9121 cattggaact tcaagaactg tttggtcagt tataactggg aatcctaaag ctattgctcc
     9181 agcacctgca gatacaacta attcacttaa tggtccaaat gcattaacaa atgcaggaac
     9241 tctattagct gtgtactcta ataatccgtt taaatcacca ggagttaatc caccgaatat
     9301 taatgctgct cttactgcaa cagatacaac gtgtataaca gaagttacat catatcctag
     9361 agggataact cttagctcaa gacccatttt tactccagct tctatagctt ggtctataac
     9421 tttaccaact aagaaagtta gtaaaccttt agattggtaa tcttttataa cttttgctgc
     9481 tgattctgca tctggacact caccaagaac aactgcaaca ccaggtatat ctcctgtaac
     9541 taatggtaca ccaagtgatc tgattatagg gtcagttata tgacctgcac atggctcact
     9601 atatggagca tccatagttg aatattttaa tgcttcaatt acttctgctg ctaaagctgt
     9661 agctaaacca gcattaaaag catgttctag taaatgagtt ctatttatta aagattttac
     9721 tacttctaaa gcaccttcta agtcccctaa agtgttcatc ttttgtcctg ttgcagcata
     9781 tatacaaggt aatgaatatg ctgtatcagg gaaagcaact ttatgctctt ttccattctt
     9841 ttctatagct tcagctaaca tagcttgagc cgcacctaaa gcttgttctg accctgtaaa
     9901 gattatatta tatagattca ttctatttcc ccctttaata tttacaccta ttttttatta
     9961 actataccct aaaaacccta gaaagcaaat ccaccttcat ttaactctaa aaaagagtct
    10021 gcatataaag atgccccgtt gattatgtca caagatttta cagttttcat taattctggg
    10081 tcacatggat tcattatagc tgaactaaat ccattagcca ttgccattgc taagaatgca
    10141 ctatctaaaa caggtctaac atgcttagga catccattag atacgttaga taatcctcct
    10201 gtagttaaaa gtcccatctc agtcatcatt tttatagctt ctaaaacttc tacttgtttt
    10261 tcttgcatac cttttataac taagcataat gggtcaaata gtatatcagt tggctccatt
    10321 cctaacatta agcctttttc taatatttct tggcagtaag ccatacgctc atcattatct
    10381 cttgggatac cttcttttgc acataaacct ataaccattg cttcgtattc agctgctata
    10441 tctattaaat caaatcttga gccagcatca gcagagttta ttattggttt tgcattagtt
    10501 ctatcataaa ctttaagtcc agcttcgata gcttttttat tagctgtatc taatgctata
    10561 ggaacattgt tgaactcaga ttgaagtaat ttgattcccc atgtcattat ttcttcgcca
    10621 tctctttcgg caggtcctat attaaaatct atatagtgtg ctcctgcttc taattgctct
    10681 tttgctcttt ttaagattgg agctgggtct ctttctgcta atgcttttct tattgaaggt
    10741 gatatacaat gtattctctc acctataatc ataaattttt ccatttataa tgtccccctt
    10801 taaatttaat attaatagtt agttaatatt ttattagttt gtttggcatg ctttttcttg
    10861 gtatcctttt aagaacttag gtaattccat agattcctct ggtcctataa ctacattcca
    10921 tcctggtaag ttatcttcta tatcaccttt aagtactgca acttttcctg gaatgataag
    10981 gtctttacaa ttagttactt cttctacctt actttcttta atgaaagcag agattgagtt
    11041 tccaccaaat ttaccagcag cccaagatgt aagaactgaa tatccacctg catctggtat
    11101 tactaaccat actggaactt ttgatctttc tatatcacca gcaactatga agtaagttaa
    11161 tgcaaagtca acagtaacta atactggaga attttcatct gggttgttga ttggataaat
    11221 ctttggttca actctcattg gtctttgtgg gtcagtgtat atgttttgtc ttagtgcaaa
    11281 taatggtaat gccttagcat aactaatatc atctattact attatagaac cgtattttat
    11341 agtgaatatt gatgataaag caacttccat catagggttt gaattagata atctatttgc
    11401 aaatactatt gaaggatatc caaatgttct atcttgctct tttaaagctg ttcttctaac
    11461 ttgtatagca ttagtgtaag tatcttttat gttttctcct gttacatcta atactaattc
    11521 tttatatcca gcagcttgaa ttaattcaac tgtttcatat aattcttcta agctaccagc
    11581 ttttacacct aatggtaaac ttgctccttt aactacttct atcatatctt tgtagttctc
    11641 tttagttgct ccatatacca ttggtctagc atcttttaat acttcaacag cttctttaac
    11701 tacttgtgca tcatcacaag ctaaaatata agctacttct aatccactgc cttttatttt
    11761 atctattaat tttaaatacg catctttatc tccacaatac tctaaaacag ccatttcaac
    11821 tttcatttgt tcaccaattc ttacatagtc aacttttttc atgttagcta ttttagcatc
    11881 tactgcttca tcactcatac aagtacagaa tgaaactgca tatctatttc tacttactaa
    11941 tgttttttca tgtctaaata atactgtttc tccacctagt tcatactcag atgcaccagc
    12001 accaactttt aaagctttca ttaaaggtgc agtagcctct gataattttg ctatagcgtc
    12061 atcagacata tgtgggcatt tacctacttc tacagctcct gaagcaacct tcatagagaa
    12121 agccatacaa gttgggaatc cacaatcctt acagtttttc tttggtgtta atttaaatat
    12181 atctaaagct tttaatgcca ttattttttc cccctaacct taacaattta attaagctaa
    12241 tgcgttaacc aattctttta tagtttctat tgattttgga tgacgaagta taactgcgtt
    12301 tgaaccacct actaaaacac ttgctgcagt tgaaacttcc attgctatag ttctttcttc
    12361 tggacaaccc caatctggct catcttctat tggagctata gcttctttaa catgacctac
    12421 ttcaaaagct actggtgtta tgataggcat ttgtaatgtc ttatcatttt gaccaaatgc
    12481 tgcaagtcta attctatcca tagtagatgc aacgtactca tatccataac caactgctga
    12541 acatccaaca ttcataacta tattttcacc tttaacgcct agttgagtta acaatacgtt
    12601 taattgttta gctaggttta tatcaacaga agattcagct cctactttat gtgcataagc
    12661 cataccagct gatgctccta ctcctttgta gttatcttct actgctgaca taaataagca
    12721 gttatgtcca tccaatgttt gagctaattt ttcaaataat ttaccatctt tttcatgatt
    12781 tcctgaacca gctacaacta aaggtaattt tattgcttca attactgcct tagctacatc
    12841 agcacattca tcaactgact tatctaatcc atttgggtca gaaccatcaa attttaaaca
    12901 aataaaatct gcttgtgtat tagcttcaac atatttagcc cactctactg gacaattagc
    12961 tacatctttg tataattcct tatatgaatc agtccagctt tcaggataaa cgtctgatat
    13021 ttgtatacct atttttggag aattacctac ttctccatca aaactataaa aaggtaatac
    13081 attttcccca cctaatttaa ttgctttttc ccctattcct acttcaactt ctgatatttt
    13141 tccagaatat ttttgagtag acattttaaa tgccatattt ttttccccct taagcctatt
    13201 ttaattctaa tttagcaaaa atttctttca tagccacttt agattttgaa tcttcaggta
    13261 aattaactaa aggaatacct gtagaatcat attcatatat caattcatcc ataggtacaa
    13321 caccgattag ctctaggtta tgcttttcaa tttcttcttt aacaccatca ttcataaccc
    13381 catttggaac tttatttaca atcaaaagta ttcttccaac acttaacttt agttcctcag
    13441 ctaaatctct tattctagca acagcttgta tgctacgtct tgagcaatca ctaaccaata
    13501 aaagtgtatc aacatgtcta gtgacttttc tacttagatg ttccatacca gcttcgttgt
    13561 ccatgactaa gtatttgtaa tgaccagata ttttgtttac ttgttctcta agtatcccat
    13621 ttacaaaaca gtaacatcct tcaccttctg acctacccat tactaataag tcatatcctt
    13681 cgccttcttc aattatagaa tttaatctaa attgaagata ttgtgccttt gtcataccac
    13741 cagggaatgc attgcctaac ttttctcttt gatttacttc ttctcttatt tctcctattg
    13801 ttgcttcaac ttcgatacct aatacttcat ttatgttagc attggcatca gcatctacaa
    13861 ctaatactgg tccctttttg tccttaacca aataatcaat caaaagccct gtgagacttg
    13921 ttttaccagt tccacctttt cctgcaacag ctatattgta tcccatttta agacttcccc
    13981 cttaaatcta gccacagagc cttatgtact ctgtctgtct attataattt aggtacagaa
    14041 tgaacacatt ctccatgtac atcatgaagt gcttccatta gcccttcaga taaacttgga
    14101 tgtggatgta ttgcatcccc tacttgttct actgttaatc ctagatgaac agcaagtgac
    14161 aactctgtca ataaatctgt agcatgaggt cctactactg ctgcacctat tatcttatca
    14221 gtttctttgt cagctataac ttttacaaat ccttggaaat gtcctatagc ttgtgctttt
    14281 ccaagacctc taaaatcaaa ttgacctaca ttgtattcta caccttcagc ttcaagttgc
    14341 ttttcagtct taccaacacc agcaacttca ggttcagtat aaacacatct tggaattgct
    14401 ctataatcta ctaccttagt cttacctaaa gcattttcaa ctgctacgat accttcttta
    14461 gaagcaacat gtgctaggaa aggagtatct attatatcgc ctattgcgta tataccttct
    14521 acattagttt caagatgttc attaactact acttttcctc tttccatttc aattcctata
    14581 tcttctactc cagaattgtc aaggttaggt cttctaccaa cacatactaa tgcatattgt
    14641 gcttctataa cctttccatt agaaagagtt gcaacagcct taccatcaac tacttcacaa
    14701 gtttgtactc caatacctgt aataacctta attttatctt tcttaaattg tctaagtagt
    14761 tgtttagcta catctttgtc ttcatttaat agtatttggt caaccatctc aactatagtt
    14821 acttctgttc ctaaggctct aaagaactgc cctatctcac atcctataac tccaccacct
    14881 actattaaca tagactcagg tatctcttca agtccaagaa cttcatcact agttattaca
    14941 acttttccat catatgggaa cattcttggt acaactggaa cagaaccatt tgctagtatt
    15001 atcttatctg cttttatagt ttctactgtt ccatcatctt tagttacttc tatagtgttt
    15061 ttatcaatta attttccaaa accattaact aagtttactc ctcttttttc aaataagaac
    15121 tctataccac ttattaattg gtttacaact ttattttttc tttccattat ggcagtgaag
    15181 tttggcttaa ctgtaccatc tatttctata ccaaaatcct ttgcttcttt tacagtattc
    15241 aatactcctg aagaagcaag aagtgcttta gttggtatac atcctgcatt taagcaagtt
    15301 cctccaactc ttcttttttc aacaactgtt acatctgcac caagcataga agcttttata
    15361 gctgctacat atcctcctgg tccaccacct actactacta tcttcatctt taattccccc
    15421 aaacctaata taatctacaa tcttgcaata ctataaacct gcggcatcca gtatagcagg
    15481 tatattctct tctgccccaa ttgccattat atgaacacca tcacataaat cttcttcttt
    15541 taattgtttg ataagttccc ctgccatttt tattccttca cttacccagt tttcttttcc
    15601 agctgctctt aatctttcga tttgttcatc tggaacaaat attcctggta catttgcagt
    15661 cataaattta gccattcctg gtgattttaa aggtactatt cctgctaata ccttgcaatc
    15721 catatccctt gttaattctc taaactttct cattgtattt atgtcataaa gtgcttgtgt
    15781 ttggaaaaat ttagcccctg cttttatttt ctttttcatt tttaataatt gaacttctat
    15841 tggagaatat tctggagtta ctgatgctcc tagataaaaa tctggagaac cttttaactt
    15901 attaccagcc atgtccgtac ctgccattaa agtctcagca gtttgaagta tccccacaga
    15961 atctaaatca aacactccct tagcttgtgg atggtctcct acgctagtat ggtctcctgt
    16021 tagtgccaac agattgttta tcccaaatac acctgctgac aacatttctc cttgtatagc
    16081 tattctattt ctatctctcc ctgttatttg aataactggc tctaatccag catcttttaa
    16141 taatttacat gtagcaagag aagttgctct cataactgcc gattgaaagt ctgttacatt
    16201 tgctgcatga actcttccaa ctaacggctt tgcacattct attaaatgtg aaaggtcagt
    16261 cccttttgga ggagccattt cagtagtaac tgcaaatttt ccactttcta atgtttctct
    16321 taataagctc atctctaatc ccccttttaa ccttctaaaa aaaactttta tgaatttgct
    16381 gctgcttctt tctttttctt tgcacttaaa cttcttggat tattttgctt agaatagtct
    16441 tttggtggtc ttatttctgc taagttatct aattgtccta tagcttctag tctttcatat
    16501 atctttatcc aagcacaatc attctctgag tttacttcac acttaccatt tttagctcca
    16561 ccacaagccc cattcataag acctttagca cacatagtta ctggacatat cccacctgtc
    16621 caaccaagtt cacagtctcc acaagcctta caggcttctt catattctcc aactctttgt
    16681 acttccccta taaacaaagt attgttggct ggataaactg gcttatcttt taaattctta
    16741 actattgtct gtgtaccatc tccacatgct aaagataaaa ctgcatcagc ttccttagtc
    16801 tcttctttta gagcctttaa atccttttta gactttaaaa ggttacaagc agggtcaagc
    16861 attacatatc ctaagatttt tttgccttca ccttcaagag tttccttcat ttttaaaact
    16921 tcttcttccc caccactttt acaagttgct gcacattgat tacaaccaac taaaaccagc
    16981 ttgtcaaaat cttttaagta ccctagcact tcttctaatg gtttattttc agaaattatc
    17041 atatctactt cccccctaaa ccttccacat atatatatct atttattgtt ttgtaattta
    17101 caagccttaa ctacatgttt tgcaagtata gatgttgtaa ctgaaccaac ccccgctgga
    17161 actggagtta tcattgatac tttgtctaaa actgcatttg tatcaacatc tccacataaa
    17221 tttccttctt catcaacatt tataccaacg tctataacta ccgctccatc tttaacaaaa
    17281 ctttcatcaa ccatcttagc tctaccaata gctgctatta gcacgtctgc ctctgctgct
    17341 acacctgata gatttttagt ttttgaatga catattgtaa cagttgcgtg ttcacttaat
    17401 aaaagcattg atactggctt tccaactacc attgatcttc caagaactgt taccttactt
    17461 ccttttaaat caacattata gtgttttaat atctcaacta ctgctgtagg tgtacatggt
    17521 ggaaatccac ttttatcccc ttccattacc ttagcagagt ttattggact aaaacaatct
    17581 acgtcttttt ccggtgcaat aacatatttt ataacttctt catttaagtg ttttggaaga
    17641 ggtctaaaac ataatatacc attaacattt ttgtcatcat taactctctt taatacatca
    17701 atatattcct cttgtgttat atcctcagct aactctaaca cttctgttgt tatacctatg
    17761 ttttgacatc tctttagtgc tcctctttca taagataaat catcacttct tgccccaact
    17821 ctaactattg ttagtttagg atttatacct tctttaacta ataaatcaac ttcttttatt
    17881 aactcttcac taatcttatc agctacaggt ttccctttta taatttgtcc tttagttgac
    17941 attccttcca tatattcaca actcccctac aagcaaactt aaattaattt attctatata
    18001 ccacatatta acaacatagt atttactttc gtcatttaaa aattattttc caagagcttt
    18061 ttcaacctta gcataaactt catcacaagt ttttacgcct tcttcaacta atttatctac
    18121 ttctgttttt actttatcaa catattcctt gtcttgtata gaatttatat ttataactac
    18181 atttaattgt ccaccaagta tagcagctct taaacactga actcctacac caacatcact
    18241 tatagcaagt cttgaacctt tatcaactaa atcttcatgt aacttaatag cttcatagca
    18301 aactcttact atgtttaatg gtacttcaca agcaactttt aatgcctttt ccattgtttc
    18361 tgcttttatt cttttttctt cttctgtttc tttaggaagc ccgtaagctt ttgataatgg
    18421 taagaaacat tctgcatcat catctatcat ttttaataaa tctttttcta actttcctgc
    18481 cttacttaat atctctttta cactttcttc atactcagca tacttcttct tccctattgt
    18541 aaggttacat accatactac ctaaagccat acctattgca cctactagtg cagcagctcc
    18601 cccaccacct ggtactgctt ctttggaaga tagtacttct acaaaatcaa cacaagtttt
    18661 atctgctatt ttcatgataa tcctccttga aaggatgtag gaaaatatct caaattgttc
    18721 gagatatttt acgaactatt ttaagatatc tcctactctt tatttataaa ttaatttcct
    18781 tagaataatc cagctattac tccattttca tcaacatcta ttttttctgc tgctggaact
    18841 tttggtaatc ctggcatctt cattatttct ccagtaagtg caactataaa tccagctcct
    18901 gctgaaattg ttgcttgtct tacagttatt ctaaatcctg ttggtctacc taatttagtt
    18961 tggtcatcag ttaaagaata ttgagtctta gccatacata ctggaacttt agtaaatcca
    19021 agtttttcta agttagctat ttccttatca gcttcaggag tataatctac accatctgct
    19081 ccataaatct tagtagctat agcatttatc ttgtctttta tagataaatc atcttcatag
    19141 cagaatctaa agttattttc ttcttcatcc aataatctta aaacttcttt agctactgca
    19201 attccacctt ctccaccttt tgcccatact tcagaaagag caacattaac acctaattcc
    19261 ttacacttgt cttcaacaag tttaagttca gcttcagtat caagtgggaa tctattgatt
    19321 gcaacaactg ctggtaatcc atatacttga gttatgtttt caacatgttt taataagttt
    19381 ggaagtcctt tttcaagagc ttctaggttt tcgttattta agtctgcttt agcaactcca
    19441 ccattgtatt ttaatgctct tacagtagca actattataa cagcatctgg ttttaagttt
    19501 gccattctac attttatatc taagaatttt tctgctccaa ggtcagcacc gaaaccagcc
    19561 tcagttatta cataatctgc aaagtgcata gccattcttg tagctataac agagttacat
    19621 ccatgagcta tatttgcgaa tggtccaccg tgtacaaatg atggtgttcc ttcaagagtt
    19681 tgaactaggt ttggttttaa agcatctttt aataatgcag ccatagcacc attagctttt
    19741 aattgtctag ctgttacagg ttcaccttca tagctgtatc caactattat gtttcctaat
    19801 ctttctttta aatcagatat atcacttgcc aaacagaatg ctgccattat ttcagaagca
    19861 acagttatat cgaatccatc ttgtctaact gctccatcac cttttttacc cataccatca
    19921 acgatatttc taagttgtct atcgttcatg tctacacatc ttctccaagt tattttctta
    19981 gggtctattc taagtgcatt tccttggtga atatggttat caagcatagc agctaaaaga
    20041 ttgttagcag ctcctatagc gtgaaaatct cctgtgaagt gtaagtttat atcttccata
    20101 ggaacaactt gtgcatatcc tccaccagct gctccacctt taacaccaaa tactggtcct
    20161 agagatggtt ctcttaaagc aactaataca tttttgtcta gtttagcaaa tgcatcagca
    20221 acacctatag tagtagtagt ttttccttca cctgctggag ttgggtttat agctgtagtt
    20281 agtattaact tagctttttt accagtctct ctttttagta gattgtagtc aacttttgct
    20341 ttgtatttac cataaagttc tacatcatct tcacctagtc ctaatttttt tgcaacctct
    20401 ctaatatctt gaggcttagc ttcttgagct atttcaatgt cagatttaaa tcccataact
    20461 gaatctcctc ccacaaccta aatagattta aaatataatt tttgtaaaaa ttgtattaat
    20521 atgtaaaaat tatattttat aagataatta tacatgtaaa attacttaaa aactagctac
    20581 taagctatta aaatattcaa acttaatagc tagttattta tctaattact tacttattac
    20641 ctatctattg cctatgtcta acctttaacc aacttaaaat cccaaatcaa aatttctatc
    20701 tattttattt atccttaagt gacattaatt tatcttttat tgctttaatc tgttctttcg
    20761 ttgtttcact agaatcatat ggagattgat tagctctatc agaatcaata acatcttggt
    20821 tataataaat aaatcctaaa gattctccat cttctaagtt ttggattata aattcttcat
    20881 cttccttatt tctaatttta tttcctacta caaatacttt atttacacct atatcatgtc
    20941 caagtttctt aacttttcta taagtctgta gacttctctc tcctggttct acaactacta
    21001 taaaagcatc tacaccttgg gctgttcctc ttcctaagtg ttcaattccc gcttccatat
    21061 ccataaccac tacatcttta ttttgtagta ttaaatgtga gcagagtctc ttcaaaagaa
    21121 catgctctgg acatacacat ccagtaccac cagaatctac ggttcccaat gtaagtaatc
    21181 ttactccatt gtattcttta cagaaatttt cagggatatc gtctacttta ggattcatct
    21241 taaacatttt tccaaatgaa cctacagaag cagctgttct atctgaaact aattttttca
    21301 tttctgatat aggtactatt gattcatata cttcttttgg aaaacctagt gctaaagcta
    21361 aattagcatc agggtcggca tcaacagcaa caactctgta tccgtcttca gcaaacatcc
    21421 tagagagcat tgaagaaaaa gtcgttttac ctactccacc tttacctgtt attgctatct
    21481 tcataatccc taccaccttt tattactatt tgctttttag tagttaattt tacagttaaa
    21541 tattttttat actctatatt tttatacact aaaaataaac tacagctagt ccttacagga
    21601 accaattaaa tttaccctac tagcttttca aagcagcatg tatagtttta ttattcttta
    21661 atattgttta tattttattt attcagtata ttcattatat tttgatgttc tttactttaa
    21721 tatttgactt tattcaactt tactcaacca gaaacttctt ataaaaacgt ttattctata
    21781 acttcactat tttttaagct tcagcctttt ctgccatttt ttcttcaact aatgcttcaa
    21841 agtgaacacg ttttttctct atatcttcta ttattgtagc tgctaactct tttggatttg
    21901 tatttacagt aaatgtagct ccaactttat cttttaattc actagttaat atatccactg
    21961 ctcttgaaga accagctatt ggaggcatta ttcctaaata agtgtctata ccagaagcta
    22021 caacatagca tcctatagca actgcttttt ctgacatcca ctctggagct atacctacaa
    22081 ctggaaggtc acacatatcc atatctaagt aattagctgc tgctccaact aaatctagta
    22141 tacgacttat atcaacacaa gaacccatat gtagtactgg tgggattcct actaatttac
    22201 agacagttgc aagaccttta cctgcatatt tttcagccgc atcagattcc attaaaccaa
    22261 acttagctgc tgctgaagct ccacaacctg tagtaactac tattatgtcg tttttgatta
    22321 attctttcat tattgttacg tgagcctcat ttgaaactcc tttagcattg ttacatccaa
    22381 ctacaccagc tgctcctctt aatactccag cttttagaca gtctgttaat ggcttaactg
    22441 ttcctgctgg gtctatatga gagtttacaa ctctgtctaa ttgatttact actgcttcta
    22501 cactataccc aactgttgcg cctgatttta attcaggtat aagtactttt gatttatctc
    22561 tatttttaaa gtttaaaata gcttctttaa ctattgcttt agcatcatca agtgcttgtt
    22621 cttctctaaa ttcaatataa gttgaacctg ttatcttagc ttttggagaa gttgttacaa
    22681 atttagtatg gtaacaatct gcaactctag ctaatgcagg gaatatacat tgaacgtcaa
    22741 ctattacagc ttcaactgct ccagttatta ttgcaagttc ttgttgatgg aaatctcctg
    22801 ctatttttac accatgtctc attgtaatct cattacctgt acaacacata cctgctaagt
    22861 ttattccatc agcaccaact tctttagcta aagctactaa gtctggctct tctgatgcta
    22921 aaactatcat ttctgataat gctggctcat gtccatgtaa tattatgtta actttatttt
    22981 cttctaatac tgctaaattc gcctctgttc ttcttggcac tggagttcca aataagatat
    23041 cgcttagacg agtacctatc atagaaccac cccaaccatc agccatagaa gttctaagac
    23101 tcatgtgtat taaactatct atatcaccag tacatcctat atgagtagag tgcattattg
    23161 ttgcaatttc tctatctata gctcttggct ctatagcgta ttctttccat attttttgtc
    23221 ttggttctgg tgcatttttt ataaatctta atgtcccaaa aggttttcca aattccatta
    23281 atgcaatttc tgccacttca tgtgctacat catagatatc tctaccttct gtctctacat
    23341 cccattcttt agctaaagta attaacttag cttcgtctct tattttatag tttccatttg
    23401 gatcagctaa tgctaatgta tgtgctatat ctctagcatg gtctgaatgg gcagctgtcc
    23461 caccagcaac cattcttgca aagtttctac ctactatagt atgctcatct gctccacata
    23521 acccccttgg agtcttaggg cttattctac atggtcccat tccacatatt ctacagcaaa
    23581 caccttgaag accaaaacca cattgtgcct taaagccttc ttttctatca tacattgttt
    23641 ctacgccttc ttctctagct ttagctatca tcttctggct gtttaaatca attgttaaca
    23701 ttttttcatc catattccta tccccttttt ttgattttta aaatccccca ggtgactgac
    23761 ttcatgtcat aaaataataa aataaatgct ttctaagttg attatatact aattttcagt
    23821 gctttgcttt agatttaaat atttttttaa caaaattaga taatacataa aaattttatt
    23881 ttctacactt aatttaagtt gattttatcg cttgtttttg gctatttgtt aatatctaaa
    23941 cctacttttt tgatacttca gtttaattaa attatgtttt gattttttta aatcaaattt
    24001 gaaatttttc tagtcatttt tatattattg cagattgttt gtgtatttat tatctttcac
    24061 tactgtttgg acttattaca gatttttact ccctaaactt aattagtaaa aatttcttag
    24121 aatagcattt tttggactaa tttttttgaa tttttttatt tttcctactt taatattaat
    24181 tatagcttca aattgaacat ttgtatatat tcatttgaag ctataattat tttttatata
    24241 aaactttttt aatacagcat taatttagac attttgacta ttttttctac tttaattcat
    24301 ttatttcaag cgatttatcc tatttcatat ttttagctac aatagcccca tatgcaatag
    24361 aatataattt agattcatgt gaatcagctc ttgacactaa aactatagga gcttttgcac
    24421 ccataattat acctgctgat ttagagtctg ccatatatgt aaaggctttc cctattccat
    24481 taccaacctc tattgttgga accaatatga tatctacatc tccagatact tcacttttaa
    24541 acccttttat ctcactagct tcttttgaaa cagctaaatc aaaagccaga ggaccttcta
    24601 caattacatt ttcaccaaat tctccttctt tacaagcttt tgctaacata tctgcatcta
    24661 cagttgcttg catcttagga tttactttct ctttagctgc caaacatgca acttttacag
    24721 tttccattcc taaagctttt gcagctttta tagaattttt taatatcttt gccttttgtt
    24781 cataatcagg agctatattc atacctccat ctgtagttat aagtaattta tggtattttt
    24841 ctaactcata taccataaca tgacttaata aactatcagt tctaagacca tagtctttat
    24901 ttaacacttc ttttaatatg acagatgtat ctaataatcc tttcattaca aagtcggctt
    24961 ctttacttga tactaattta actgctattt ctgcacactc tttgatatca tccttatcca
    25021 ctattttgat accacttaaa tcaaatccta tttcttttga tatttctctt attttgcctt
    25081 catttccaac caatatagga gtaattatat ttctttctac agcatccttt attgccatta
    25141 aaacttcttt atcatgagct gctgctacag agagtacaat tttctctcct cccttaagtt
    25201 gttctaaaat atcatctaat ttttttatca aaagtaaccc ctcccttata tatatttaac
    25261 taaataatac catatttgct ataccttttc tcaatttatt ttttatgtta taaagaattt
    25321 atataactaa aagacagttt aatattttat tctgggattt catcaatagc tcttaaaagc
    25381 tttgcaggaa caccacctac aatagtattt tctgcaacat tttttgttac aactgctcca
    25441 gcagcgataa ttgcattatc tccaatagta actcctggaa ctcttcatac aaaaaagagg
    25501 cttatctcta ttttgagata gccccactta accaataaaa ttaaatacaa cttaacaata
    25561 tccttactta tttattccaa gttctcttag acaagcaata gtaatttcat cttgtggatt
    25621 taattcataa gctctttcta tatagtaagt tgcatcatca atatcaccat tatttaaata
    25681 agccattcct aaattgcaaa gtatttctgg gtcttccttt atcttagccg cttgttcaaa
    25741 atactctatt gctttatcta aattattctt ataagcctca caaagcccca attccactat
    25801 agtatccacc tgattaggct ttattatcaa tatcttctca agatacatct tagcctgttc
    25861 tatttcgccc atacccttat atccaagtgc tatcataaac agcaagttcc accaatccat
    25921 atgttcttct tctaatggaa gtaacttctc taatccttcc ttaaacttac cttggaatac
    25981 aagtgtatat ccttcttcat attgaacttt aaagtccatc ttgcccagat tctcttgtac
    26041 ctcagctact aaatcagcat ctaaccctag ccttaacgct tcttcccaag tcagcttagt
    26101 ctttaaatat tgaccttgat tataataatg gtagcctaag tgataataac ctaatgcaaa
    26161 attctcatca acatcaattc ccttttcaag cttagccatg gcttcaagta agaatgcatt
    26221 cattgcctta tcatccatat ctttttgata ctgtttagct atctcttggc aaacaatcgc
    26281 atagttatac attgcatcta aatcatctgg atacattgtt ataaatgctt ttatatatat
    26341 taaagaatct gtatgttcac caatctcaaa gtattttctc gacatatatc ccatatacga
    26401 tttcaaatcc aaatcaatat cttttgataa agcatttaaa aacttctcat actctgcatt
    26461 gtttttaaac ttactatcta ttccaattat atatatcatt gcatctgcta tagacattga
    26521 atttaactta tcttgagcag tcttttcttt tatccctttt actaatacct cattttttat
    26581 aggtacatct aatccacctt ttggcacttc atagcttttt aatttaaact ctccaccatg
    26641 ttttatagtt ataaaagcta attcttctgc tttttttagc aaatattttt ctatcttaaa
    26701 atccatttta tcctcctaaa tacttaaatc tctactttat gagttttaga tttctcaaat
    26761 atttttttat catcatactc aaataagact acattttcta cttctcttat ttctgtattt
    26821 atatcatttt ttaaatccac aacattaaat ctaaatggct caaaatgaac atattttatt
    26881 atatgtttag ctggtttatc aacaaaacta ggtaaatatg ttgataagtt atcattatct
    26941 tgtaaaaata catggcatct attcttaaaa tcatccacat ctagcttatt aaaaaactgt
    27001 ggtatatttg atgttttacc cagtgatata tagtcatatt ttaatatatc gttgaataca
    27061 tcattatcta tgttgatttt ttcattatag aaatccatca atattttata taactgattc
    27121 tttccttgtg ccaaatcaaa gtagccattt tcatcaaaat acttggcaaa aacctcaaag
    27181 aatttaaaag ggcttttttt ataaaatctg cctataatat atctcataga taacacaaag
    27241 tttttagaat tgtagtatct ctccagtata tcttctatat cctttagctt caaagtttct
    27301 tcatagctta tataattatt gtataaaaac tcatatggag cataatcctt atatttaaaa
    27361 ccatgctcat ctgcaacttt tctcatacct gtccctttaa tcatctttaa aaagcctaat
    27421 tgcagatgct ctatacctag attaaataca tcattaaaag aattttcaaa gctcttataa
    27481 tcttcataag gcagtcctgc aattaagtct aagtgctgat gtatatttct ataagatgct
    27541 acagtttgta caacatgaga caacttttta aaatcatccc ttctacctac tgcatcaagt
    27601 gttttttcat tcgttgactg aacacctatt tcaaattgaa aaagaccttc tttacaatca
    27661 gccaaaaact caagcatctt atcatctatc aaatacgctg taacttcaaa atgataagtt
    27721 gtatatccat tatcattttt cataagaaaa tccatgattt ccatagccac ttttctattt
    27781 gcattgaatg tcctatctat aaactttatt tgtgatactc ttgcatctat taaagctttt
    27841 aaatcactct ttatcctgtc taaactaaaa taccttagac ctggaatagt agatgataaa
    27901 cagtattggc agttaaaagg gcaacctctt gatgattcat aatacactat tctattttca
    27961 tattcttttg gattcaagtt ttcataagga ctaggaatct catccaaatc ttgaagtaat
    28021 tccataggct tattcactat tatctcattg ccttgtctat atacaagtcc atttacatca
    28081 tttatttcca tctttccttg caagtgaagt actaagtctc taaaaattaa ttctccctct
    28141 ccataaagta tataatccac aaaatcatac tttttcattg cctcataact atcataactc
    28201 acttccggtc cgcccaaagc tattttagta ttaggtctaa ttttttttag attatcacaa
    28261 agtttaacta tatctcccac attccagata tatgttgaga ataatattat atcatattca
    28321 tttttatata tatcctttaa aatatagtcc aaatcgttgt ttatcgtgta ttctttcata
    28381 ttaacttcta tcaaatctct tacaaattct tttagatatc ttatagccaa atttgtatga
    28441 ataaacttgg aatttaatgt tgttaataaa attttcaaat atttctcacc tctttttaag
    28501 attatactgt ctttttgtac cccttatagg ttaaaatagt atatgtaaag tctaaataat
    28561 atctatataa ttaatttatt aatttcaagt aatgtgagga aaggaagttt tttatggaat
    28621 taattgaaaa agtatctatc aactctttat caaaaagaga tttactactt attataaagt
    28681 ctcttgaata cactaatgaa aatactcaaa ttagtgattt cattgacctt aggaataata
    28741 tagtaaagga attatgtttt ttaactgaca ctaaggaaaa agatttttta gattatctag
    28801 aaaaaaatag cacactctaa taacctaaac ctttttaaac tttaatatat aaatacctga
    28861 tttagaattt atttttatgc ttaatatatt atcattaaag gttttcgaca taactgttat
    28921 ttgattaaat atagggtcta ttatagtatt accttcttca agtcttataa gacttcttgg
    28981 gtctatgctt ttattatatg ccttaactcc aattttatat tttctcaatt taacaacata
    29041 ttcggacata gaaaaaataa aatctatatt atcttcattt aatttactat cttcacccaa
    29101 aatggataat atagattttt ttatgctatt aattccttca ttttctacag ttctatcttc
    29161 catatataca tcatatagaa catttaaaac atttaataaa atactttctt catcataatc
    29221 ttcagatttc aaatcaatgt acttatcaat taattgtatt gctttaatcc ttgccatctg
    29281 aaactttaca acatctgatt tgtctaattc tatagaaaat cctattatct tgtctttaat
    29341 actctgtagt aattcgacat attctatttt gctattattt ataagattgt gcataatgga
    29401 attatacacc acagaaccta ataaataatc aaataaaagt tcttcttttt taaaataaat
    29461 aacatacttt tttattagtt taataacctc atcttcactt ttttgaatat tagtatttga
    29521 taaaattagt ggtaataaaa tatttaaaaa attgatattt cctatttttt ctccataaaa
    29581 tctatagtaa ataagttcat ctctcagtct attttcgtct atatacacac atctttgcgt
    29641 tttatcatct attaaggatt ttgtatttat tatagttaaa tctttaagag ccctacttgc
    29701 actactaaaa gaagatgtgt agactttttt tagtaattcg tcattcataa atatatcctt
    29761 tctgaaaaat tgaatgtaaa taaattgtta ttaaaaaaaa agagacagcc cgtttaagaa
    29821 gctgtcatat atagggggat agtagtgtac aaaaatcatt gtaatctact atctatatat
    29881 tattatacga tactactttt ttatatgtaa agcatcagtt ttcgacatcc ctatatttta
    29941 cagttataca aattgcgtac taagttcaat tttattcttt ttatttcaac attttatcat
    30001 gctacattct ttcaggagcg tgcattccca acaatttcag agaattttct aaagtttgtt
    30061 ttgttgctaa aactaatgca agtcttgctt ttcttatttc caaattttct actaaaattg
    30121 gattgtcatg ataaaattta ttaaacgctt gagctaaatc tagcataaat ctagtcacta
    30181 tatgtggctc atttttcttt agagcaagta aaatattctt attgaatgat tctataactc
    30241 taagaacttc tgcactatct tcatcagcta atagactata atctatatca gaagtcactt
    30301 ctacttctgc ttttcttaaa actgcacagc atctagcatg tgtatactga acatatggtc
    30361 cagtctcacc atcaaaacta agcgttcttt cccaagagaa ggtatagtct ttaattctac
    30421 tattagataa ctcttggaat actactgccc caacacctac ttgcttagat atttcatcca
    30481 catttttagc atttgggttt ttagctagta taatttcctt agttttatct atagcttgat
    30541 ttaaagcatc ttctaaaaat actactcttc cttttctagt cgacatagta ccttcttcaa
    30601 gtgcaaccat accaaatcca acatgaatta aatcttttgc ccaatcatat cccataagct
    30661 caattacctt aaaccattgt tggaaatgta agttttgttg agaaccaact acatatatac
    30721 acttgtcaaa atcataagtt tcttttctat atattgcagc agctaaatct cttgtcatat
    30781 ataacgttga accatcattc ttagtaataa gtgctggtgg cattttatac tcttctaaat
    30841 caacaattct tgctccttta gactctttta aaagattttt ctcttctaat agttcgataa
    30901 ctctgttcat tttatcagaa taaaaactct ctcctgctaa agaatcaaat tctatatcta
    30961 aaagtttata cactctgtta aactctttta aactctcatt tctaaaccat tgccataatt
    31021 cttgtgcttc ttcgtcacca ttttctaatt tattaaacca tgctcttgct tcatcttcca
    31081 tttctgggtg ttgttcagct tcatcatgga atcttacgta taattttagc aattctggaa
    31141 ttggattaga ctctactact tctttttctc cccacttttt aaaggccact attaacttac
    31201 caaactgagt tccatagtca cctaaatgat ttattcttat agtcttgtat ccttgcgaat
    31261 catatatctt atataaagca ttacctataa ctgtagttct tatgtgccct atatggaaag
    31321 gttttgctat atttggagaa gaatattcaa ctattacagt tttatctttt ccaaaatcac
    31381 tatgtccgta attttctttt tcatctaaaa cttttttaat tacagtttct gctaattgag
    31441 atttatttac aaagaaattt acatatccgc ctaattgtat tacttttgtt atctctccac
    31501 ttggttctat actttccgcc aattcacttg ctatcatgtt tggagctttt ctaaacactt
    31561 tggctaattt aaagcatgga aaagcatagt cccccatatc cttatttggt ggaacttcta
    31621 taagtgcctc tatctcttct ttcgataaat cttctatttt ttctttaagg caatttgata
    31681 ttgccacctt aaaatcttgc attctgttgc tcctctctac attgttcctg gtttatattg
    31741 tgcttatctc tttatgttaa atcaaatttc gtgttttttc aagtatttca ttacagtgta
    31801 aaacacttta gtaattatgt tttctgtata tattaaaaat actataattg cagtttttaa
    31861 tcacactatt attgattttt tataagactt ttttctattt tattgtttct tgtactatcc
    31921 agttgacttt atatactttt tttactcttt tatctatttt ctataaatct ttttcactct
    31981 taacttttat tccttcttct tctaatagcc ttgctgttat acctttccct ggtatttttt
    32041 tacctgaaaa actaccatca tatattagat tacatccaca agaggggcta ccctctttta
    32101 gtattgcttc gctacataca tataaatttg ctatttttag agtttcatta gcccctctta
    32161 caaagttttc tgttacatcc ttattatctt tagtaattac ttttccatca actatctcag
    32221 caggtggtct tggtgtagat agaccaccta actgctctgg gcatacaagt gtaaattctt
    32281 tgccttttaa atattccttg actttttcat tatcattatt atcgccacta tatttacaat
    32341 ttattcctat taaacatgca gataccaata tcataaaaat gtgctcctat acaaattctt
    32401 aatatattct catacaaatt actaatgtat tcttatacaa attattttaa tttaacaatt
    32461 gttactcctg ctccaccttc tccatattga ccacctcttt gtgattttac atgtctattt
    32521 cttcttaaaa tgtcttgtag ccctgctttt aatactcctg tacctattcc atgtattact
    32581 gttacagact ctaaacctgc cacatatgca tcatcaagat acttttctac ttccattata
    32641 gcttcttcta ggtttaaccc tctaaggtca acttcatttt ttacactacc agattttgac
    32701 cttataatgt ttctcgttga tttagttaca tttgttgaaa catctttgcg tgttttttgt
    32761 aaagatttaa aaggtagagt catcttcatt ataccaattt gcactactgc ttcttttctc
    32821 tttttatcta ctgaaactac actaccattt tgatttaaag ttattacctt aacttcttca
    32881 cctggcttta agtcttttat ctccttattt gatacctttg gaactatcat actttttact
    32941 gttggctgaa gacttcccat agagctggtc aattcttttc taagttcttc tatcttacga
    33001 ttcttttctt ttgaagctct ttcttgttca agacttctaa gttcttttat tataatatct
    33061 acttcttctt tagcttgtct tataattgaa aatgcttctg atttagcttt ttcaatcatc
    33121 ttatctcttt gactgaccaa tttttcaagc ttttcgtcat actctacttt cagtttttca
    33181 atctcttctt ttaatctttc agcttcttct ctatcttcta ctgctttgat tctattcttt
    33241 tcaacattct gtaacacatc ttctaaagct atgttttctg tatttatata ttctttagca
    33301 cgtgaaatca cataatcact tagcccaagt tttctagaaa tctcaaacgc atttgatttt
    33361 ccgggaacac ctataagtaa cttatatgtt gggcttaaag tttctatatc aaattcaact
    33421 gctgcgtttt ctacacctga tttagtaaga gcataatttt taagctcact atagtgagtg
    33481 gtagctatac atttagctcc tacagaattt atatcttcta atactgctat tgcaagggca
    33541 gctccttcaa cagggtctgt tcccgctcct aactcgtcaa atataactaa agagtctgct
    33601 gttacgtttt gtaatataga tactatattc gtcatatgag atgaaaatgt tgatagactc
    33661 tgttcaatac tctgttcatc tcctatatct gcaaatacat tatcatatac acacatacta
    33721 cttccataat cagcaggtat atgaagtcca ctttgtgtca taagtgcaaa tagacctaca
    33781 gtttttattg taacagtctt accacctgtg tttggacctg ttatcaccaa tgtatggaag
    33841 tctcttccta aataaattgt atttgctact accttctttt tatccagcag tggatgtctt
    33901 ccatttttta tgtttaaata tttatcctca tttaaagttg gttctattcc tctcatctgt
    33961 atagaaagtt ttccctttga aaatgcaaag tccaatcttc caagtatctc ttgattagag
    34021 attaaatctt cgctcacttc tccaaccatg gcagaaagct ctgataaaat tctttctatt
    34081 tcctcttgct ctcctagttt caactgcctc aattcattgt tcatctctac tatagtcatt
    34141 ggctctataa aaagtgtcgc accagaagat gactggtcat gcactatacc agctacttgc
    34201 gacctatatt cagattttac aggtactaca aatctatcac ctcttagaga aattattgca
    34261 tcttgtaagt acttttgata agtagttgaa cttattattg aatttaattt tgacctaatg
    34321 gattgatttt tttgggctat tcttcttctg atatctctaa gtgtacttga agcattgtca
    34381 gatatttcta cttcactaat tatagcattg tatatctggt cttctatgtc cttgtataca
    34441 tatagagaat ttgatagaga ttgtattatt ggataattaa aatcttcttc atcactacta
    34501 gataagctat ttcttaatct tctagccact cttaaggtat ctgctatcat aatcagactt
    34561 cctgggtcaa gagaagcacc tatataagct ctctttacct tatcttctat atcatgaata
    34621 ccttccaacc ctactgaacc tctctttata ataattgatt gagcttcact agtttcttct
    34681 agcatagatt tcacttctac aaaatcagta tttggtacta aattttctat atattttaga
    34741 cctaaagaag atgaggcttt cttctttaac aaatctatta ttttattgta ttctagaact
    34801 cttaacgatt tctcattcat tttctatatt caccatcctc gatattttaa cttttttatt
    34861 taattttaaa aatgtatgtt ttcaagcatt tccaataaaa actgcaagtt ttatttcttt
    34921 ttcatttcta aaattattat attttttctc ttttagatat attttacaca tattttgtat
    34981 tatactatgt atgtagctat ctatatatta tacataaaca tgctttattt gtaatataat
    35041 ctgttaaaaa atcttcttta atatttttaa aggagtttat tttagcttat aaaaaaaaat
    35101 agctacttat atagataaat taaggaggaa catgagtcat gggaaacgta ttagaaggat
    35161 taaaaccaga aagtgttttt aaaaactttg agaaaatatc tcaaattcct agaggttctg
    35221 gaaatgaaaa aggcataagt gattttttac ttagctttgg taaaaattta ggtcttgaaa
    35281 ctattcagga tgaaagctta aacataataa taagaaagcc tgctacaaaa ggatatgaaa
    35341 attgtccagg tgtagttctt caaggacata tggatatggt ttgcgaaaaa gaaaagaatg
    35401 ttgaacatga ttttcttaaa gaccctataa aattaagaat tgatggtgac atgatatatg
    35461 ctactggaac tactctagga gctgacaatg gtatagctgt tgctatgggt atggctatat
    35521 tagaagataa tactttagag catcctgcac tagaagtttt agttactgtt aatgaagaag
    35581 atggtatgaa tggtgcagat gcactagacc ctagcttaat taaaggtcaa tatatcctaa
    35641 atatggactc cgaggaggaa ggatacttat tagttagctg tgctggtggt aaaacttgtg
    35701 ttgttagttt acctgttgaa tacaaaaaag ttgaaggtga caaacaagga ttattagttg
    35761 aggttactgg actattaggt ggacactctg gtatggaaat tgttttacaa agagcaaatg
    35821 ctaacaaagc aatagctaga gtattaagtg tattgaatgt tgattatgaa ttagcttctg
    35881 ttgatggtgg tactaagcac aatgctatac ctcgtgaagc taaatgtgta atagctgtta
    35941 ataaagctga tgttgaatct gctaaaaaac aaataaatga cattttaact gcatttaaac
    36001 atgagtttac tacttctgac cctggcatga cttactcagt agctgaaact tctgtagaca
    36061 aagttcttac taaagattgt aaagaaaaag ttgttcaaat gtcttgctta actcctcatg
    36121 gagttcaatc agtaagtctt gatatagaag gattagttga aagttctact aacttcgcta
    36181 taattgaaac taaagaatct actattgaat ttttaacttc tgttagaagt tctgttatgt
    36241 ctattagaga tgaaatcgct gatagaataa gacttttggc tcaagcttta ggtgctaatt
    36301 acgaccttat agctcaatac ccagcttggg aatttaaaaa aggctcaaaa ttagaaaaaa
    36361 tatgcagtga aacttatgag aaattaactg gtaaagttcc tactgttatg gctctacatg
    36421 ctggtcttga gtgtggatta ttacttgata aacttcctca tgctgaagct atctctatag
    36481 gaccagatat gtttgatgtt catactccaa atgaacatgt tagtatccct tctgtagcta
    36541 atgtttggga ttatgttatt gaaatattaa aatctatgaa ccaatattaa atttaagttt
    36601 tgattctaaa tagattttaa ttttaagtaa tctatataaa attaactctg taaattaata
    36661 ctactgttag tataatattt actttcaata ttaacttata gaaataaagc ctaatgatag
    36721 ataataacat gtatcattag gctttattgt aatttaaata ttattaagct ttattctgtt
    36781 ttaaaattaa ttcttatact attttgaatc tatttcttcc ttgtctctta gaatcataaa
    36841 gagcattatc tgctatttga tacagttcat catactcttg accaggcttt gctataacta
    36901 cccccatact aatagataaa ctttctccat ttggcaactt aatgagatga atatgattgt
    36961 atacatcatt acatttatta ataagttctt ccttatttat tatatcattg atataaacac
    37021 taaattcatc tccacccaaa cgacctacta tatcattttt tacaaaactt tcatcaagtg
    37081 cctttgcaac atcaataagt actttatctc ctaccaagtg accataagta tcattaatcg
    37141 acttaaaata atcaatatct ataatcaata aagcaccatt tttttcagtt gataaattca
    37201 acaaattttg tgcagttaat tttctaatat atgctgcatt ataaatattg gttaaactat
    37261 ccctttgagc cttatctaac aatctattct tttcctcttt ttcagaatca atattacata
    37321 ttttcccgat tacatacatt ggtatttttc tatcattata aattattttt gaagtaactc
    37381 taatccaatg aaaagtatca tcaagcataa tagaatacat ttcagttgtt ccattttctt
    37441 gtgattttat tacatcaaaa aactttttat tatattctct ccttatttta tctctttcat
    37501 tttctatatt gccattttca ctttccttat catttttatc caaaccataa taagtctcaa
    37561 tacccttttc tggcatagaa attatcaatt tatcttgctt ataatcatac tcaaaaaagt
    37621 attcacttgt catttcatac aactgagtat gttttttgag ttctaaagat atcttctcgt
    37681 tcatacttgt acgagtatgt aagccaaatg ccataaatcc aataatacaa attaataaac
    37741 tggctacaat aaaaatagtc tcaattggat tctgttgcat aatataaagc aacgagaaat
    37801 cttgtctata tgtagtattt tggtagacaa ttgattgcat tttttctgat gaaatactta
    37861 taatagcttt attaaatata ttcaataatt cttgtttatc ttttttaatt ataccaaaac
    37921 aaatactctt tgctttataa gtttgaggaa ctagacgcac atttttatac ttaggttgat
    37981 tcatatagta ctgcatagaa taaccttctc cataagtgta atctgcatag cctttattaa
    38041 cagcttctat acactcttct aaattatcat accaaactat attctcttca aactgaccat
    38101 cataattaat acctttggtt agagctatac attttccatc taaactattc tcatttaatt
    38161 tattattaat catcatagta tattgagtag aaataaaagg ccgagacata gctatattat
    38221 gctcacgaga gtattcataa tcataaatca ttcctgctat aatatcaatt tcatgttttt
    38281 tagccatatc ttccaaatct tcttgagatt ttacaggcac aagttcaaat tccaagcctg
    38341 ttttatcaca tatgtgattt aacaaatcaa ttgatatacc tcttaattca cctgtatctt
    38401 tatctgcatt ttgaaacggt ggtttgttta aaagtactcc tacttttaat ttttctgtat
    38461 ctttaatgta attagtttct tcatcagata aaaacatttg attattctct ggcgtaaagt
    38521 atttctcata taaagtagtt gaaaaatatg ggtccttctg ttcaatatta ttaattgctg
    38581 aattaagctt ttgagttaag tctgtactgc cttttggggt aatgaaataa aatggttttg
    38641 atgagaattt tgctacagta cgtacacctt ctattggatt catactaaca ttaagaagta
    38701 catctgcttt accactcttt agtgcctcta attgctcgtc acttgtttta caatatacca
    38761 attcaggtga catcagattc attttacaat actcatctaa ctctttaaat ctagtatcag
    38821 aattttctat tacagcaata cgaatttttt tcacactttg tgaactcatt atgttatcaa
    38881 tatctgtatt ttcatataat gcttgtagta ctgtatttgc tactccataa ctatttcctg
    38941 cataattata tattttttgc attggctcat tgtataacat acctcccatt atatcaattt
    39001 caccattttc taacatcttc attaattttg taatagattc atttatctct ccaggaactt
    39061 gaacaaattc ataattccat ccagtatact gtgcaatttc tagtaaatat tcatatgtat
    39121 acccaaaata gttaccttgc tcatctattt cagttaaacc tttttgaata ggataagcaa
    39181 cacgaatggt acgattatca ttacctatag cgttgatacc aaaagaaaat atgcaagaag
    39241 tgaatataga tgtaattaca ataattaata aaagtaattt ttttaaattc actacacaat
    39301 cctccatata gttaagattt acagtataaa ttactgcata aacttgtaga catgtaaaaa
    39361 tagattagta tataaaagga tatataaatc tacttagaaa tttaaatatc cttaatatat
    39421 acaatatatt taaattataa ctcatttata tgtctattac aacaaattta ccctgctaaa
    39481 tacctactct atatcccata attttacaag ttgtagtgaa gtttaagttc tatctcacct
    39541 caaatttagc agtgtttcta tttacagttc ttttatattt cacatctgga taacccaata
    39601 taaatgaagt gataacagct tcgttctcgc tcattcctaa cagttctttt atctttggct
    39661 ctacatttga tgccataaca aaaaatccat tataacaaat tcctaatcct tgagaatagg
    39721 ccataagttc catattagat gcagccagtc ctccatctac ataagcactt ccacctagag
    39781 acatatcacc tacaactacc ataagtagtg gggcatcata aaataaagaa tcatttccgt
    39841 tctctttata tcttttgtac attttcttaa atgtattttt atagatagaa cgtacagggt
    39901 cattgtcatc agtatctaat gccaaattat aaagaccttg tattgccagt tctttcactt
    39961 cttttagctt ttcttttact aatatgtatc ttataggctg tctattacca cctgttggtg
    40021 tgtatctacc agcttccact atgtttttta ttttttcttc ttctacctct atatctttat
    40081 attgtcttat acttcttcta aatttaataa aattcaataa cttttcgggt tctaattcaa
    40141 aactttcacg attgtattct attacttcat ttttatcaaa tccttgcatt tctattgcat
    40201 ctgttgggca aattgccata cagtgaccac agttaataca gagaatattt ttaacctttg
    40261 ctttatcatc cttaactttt attgcattta caagacagtc tgattcacac atcccacagc
    40321 ctacacattt ttctaaatta atgtctatca ttccaaatta ttcctccttt taaaaaattt
    40381 actttagtat aaaacaaata gttgtctaag tcaattttta tttttttaac aatatactag
    40441 ccttaactac actttaatgg agaaaaatat acataaattg gaacttaaat tagaacttat
    40501 tcaaagtaaa agataaaaga agtagatgtc taaaagtgaa ctttttagtt aattagatat
    40561 tctttattgt atgaaatcaa gtggatattt atcatttcaa caataaaaaa ggcttacctc
    40621 tattttggat atgtccctgt caagtagaca gactaaaaaa aggctatctt tacgcactga
    40681 gatagcccct tttctcaact actattgttt atcttaatat tagtcaataa atttaatttg
    40741 ctataacctg taagttacat tttaatttga tgtaacttta aattacattt ttaagtaata
    40801 tctttaaatt atattcttaa aatatatcat taaactacat tttaattaat ctaaaaacta
    40861 tatcttaatt aatctaagaa acttacatta taatctttta gtttcccatt atcatataca
    40921 atctttgcac taaagatatt tccagtctta gcccaattta agaacagcct gtcaccttcc
    40981 cacatattta aatcgaatat tttatcatta tcaacccaaa ttaaatttcc ttctttacaa
    41041 tcatttaaat ctttttcaga taattcacct tcaaactcat ctgagaaata caaaaacata
    41101 taccaatctt cttcatcttt aaattttgga aaagttatca accctttata tgacaatgat
    41161 ttaagagtaa gaccagtctc ttcttttact tctctaatta cacattcttc tggagtctct
    41221 ccttgctcaa actttcctcc aactcctaca tacttacctt catgtatatc atctttcttt
    41281 ttatttctgt acaacatcaa agtcttgtca tctttttcta tataacaaat agttgtaagt
    41341 ttcatgtatc tcgccttgct ttctctttat attctcaact aattattttc agcactttca
    41401 agcacatcac ttatattctt cattgcatta agagaaagct ctgcaaattc atcaaatgga
    41461 atccctatat cttctatact tctcattgca tctctattta catttgaagc aaatctcgtt
    41521 tctttcattc ttttaataac agacttagtc tttacactgg taagtttttt atctggataa
    41581 actaaagcta tagcagttat aaacccagtt atagggtctg ctgcatatat tgctttttcc
    41641 attaggctag ttcttgtaac tcccattcca tcatgatgac caagtattgc tctatacatt
    41701 tcttcgtcac cgaagttttc ttttttaagc agttctactg ttgttgtagc atgtccttca
    41761 catatttctc ctggctttct tccaactata tctgaatcca aatcatgtaa aagacctgcc
    41821 actgcccact cttcttcttt ttctggctct agtcttttgg ctaattctct cataacagct
    41881 tcaacagcat aacaatgttt tctcattcta tcagtttcta aatacttaaa taaaatttct
    41941 aaagcttctt ctctcatttt caccaatccc cctgtttttt cacatatatg atatttttat
    42001 atattaatac acataaattc aagtttttat atatattcat gtatattttt catgttatat
    42061 ctattctaca cctttatagt agtgtcctgc aactgttcca atttcatcta atttcttata
    42121 caagtctgta gccttttttc caagtttata attattactc aatacctcaa tgtgagcttc
    42181 aataaccttt ttaaccatct cactatcttc aactgtaaaa tctatcctaa atacatctat
    42241 tccaatttcc tctaactcat atagattgtc caacatacaa gtaaccttcg aattgtaaat
    42301 tgtacttcta cagaatatat cttgtgttat cctataactt gcatccgtaa agtctcttaa
    42361 agcataacta ctttccttac atttagcaac tctcttgtcc tttttacaat ctctaacaac
    42421 tactcccata ggacagtatt ctgtaaccat cataggagca tatccatata ttactgcttc
    42481 aatttctaca tctgtatatt ttaaagtttg tttaatttca tttaagttta gttcttgtga
    42541 caaacaaact gtacttgctc cctcttcttt gaagtgattt atactttcac tattgaatgc
    42601 atttaagtag caatctatat ttaagtcttt tttcttaaag tattccatag agccccagtt
    42661 accaatttga accttattaa ttccttttat attatccaat atctcaaatt gcttgtactc
    42721 tttatttcta acaatccttg gtgctgaata gattaatttt ttgtcagtga ctgctgtatt
    42781 atagtggttc ttattcaaag tatctatttt acttgtattt gacaaagtat ctatgttatt
    42841 tgtatttgaa cccattagtt ctttaggagt acctaaagac gaagaagtat ctaaatccat
    42901 agaaatactt gaatctatag aaatatttga atctatagaa atacttgaga ccatttgtaa
    42961 agcttttgat aatgtattta tatcttcata atagattaaa tctacattat aatttaatac
    43021 tgcttctaat tgctccaagt tcttaacttt aactctaatc ttaggaactg tatcaagttt
    43081 tttctgttta tttactctac ttggctggta ttttaatcta ttcttcttaa attttctatc
    43141 ttttatcttt attctttctt catctaaaag ctcaatacaa tcccttctca tttgatttaa
    43201 cacacttata ggcatactta caccttcatc caggtcaatt tctatctctt ttaacttata
    43261 tggtgtattt ccaagctttt gaatttgtgt ttctattttt tctttactta aagccacctt
    43321 tatagctttt tcaactattt tgtctccttc taccaccgat ttatttccac aaaaatcact
    43381 tataaaaagc tctggctttt tacctagttt aagactcact tttgcacgta tattagtttt
    43441 tatgaactct ttatcttgct gaaatgtagc ttgtactcta tccattaatt cgctgtcaga
    43501 agtcttatat ataagctgat ttctctttgc ttctccaaca aaatctaatt ctatcaaatc
    43561 ccctttatgt gctattgtag ttatctctcc atcctttatt attcttccaa tagtacctcc
    43621 acctaagtta attccatcac ctttcttaag cgtattttct agcattactc taagtctttt
    43681 gttctttcta ttataatcta aaacttttcc aatatatagc ccttgattat taggtctatt
    43741 agagttcatt atatccttac caacttcacc taatatatat ccttttgtaa actttctatt
    43801 aaatatggta tacaaattat ttattatttc ctcagaaata cttatttttt tcttatctac
    43861 aaattcatta atcgcttctc tatatcctga aaccacagta gctacatact ctggcttttt
    43921 cattctacct tcaattttta aagataatac acctgcttca attattttat ccaaatcttc
    43981 tatagtactt aaatctctag gactcaacaa ataatctcca ttacttttta ctacttctcc
    44041 tgtatttata tctatcaact catacttttg tctacatggc tgtgcacacc tacctctatt
    44101 tccagaccta ttgcctatca tactactcat aaggcattga cccgagtaac atacacataa
    44161 agctccatgt acaaaaactt ctatatctac agttgtattt tcacaaatcc attttatctc
    44221 atcaacattt aattctcttg ctaaaacaac tctattaaac cctacactct gaaggtattt
    44281 tacatcttct aaggaatgtg ctaccatttg agtgcttgca tgtagttcaa agtcaggtaa
    44341 tagttttttt ataagtcttg ccattcctat atcctgtact attaaagcat caatatctat
    44401 atcgtataaa aattttacat actctacaaa atcttctatt tcatactgtt ttatcaatgt
    44461 atttacagta acaaagactt gcactcccct tatatgagag tatttaacag cctcaatcag
    44521 ctcatttcta tcaaagttat ttgcagatgc tctagcacta aagtctttac cacctaaata
    44581 cacagcattt gctccgtttt gaactgctgc ttttaatgaa tcaaaagagc ctactggtgc
    44641 aagtaattct atttttttca tatttttctc ctctatttat acttgttagg ttaatataat
    44701 tatatctata acttaaatat ttgtattaaa tttatatatt tcttactata ttttaaattc
    44761 ttcaattaat ttatatactg cttactaaat ttaaaacatt ttaattaatt tgtacactgt
    44821 ttactatact tgaaatactt ctattaatct atatattgcc tactatactt aagacatttt
    44881 aattaattta tacactgttt actatacttg aaatacttct attaatctat atattgccta
    44941 ctatacttaa gacattttaa ttaatttata caccgcttac tatacttaaa atacttctat
    45001 taacttatac attgcttact atattttaaa ttctttaatt aatctataca atatttgcta
    45061 tatataaagt atatcaaata acagcttcat ttttttgtaa atttacagaa agttaatttt
    45121 cattaaatga atcatcttta ttgataaaca taattccaaa gaccactgcc aaaataaaaa
    45181 aacatattag tattgatttt tccacgaaaa tttttgtaaa aaaagttcct aaaatagctc
    45241 cagatataaa gaatataata atagcataat actgtaaact cttttttatc ataaaaatat
    45301 tcttagtatg tatataatga aataaagttt ctgtagcact tcttaaattt ccagtacaca
    45361 ttgtcgttgc aaaactattc ccatttactt ttctaaaact ctctacttgc attgaacaaa
    45421 taaaagaaat agcaacattt acaaacatat taaatcttcc tctaggaata aatgaaacaa
    45481 taagtattgt aatcatttca attataatga taacctgacg ccaatgaatc tttgtcttat
    45541 tatttgtaaa atactttctt atcttctcgg ctataaatac acctaacata aatgccaaaa
    45601 taggaatcaa ataataaaat gattccttta cattaccttc tgctatatta agcccaaata
    45661 aaactatatt tccagtttgt gcattagcaa agactttacc tcttaccaca taagtataaa
    45721 tatccaaaaa tcctcctgtt attgccaaca aagaacataa aaagaatgat tcagacatct
    45781 gactcttgct tgtcatatat aaacctctcg ctttctaatg atagatacaa aatcaaaatc
    45841 attttagatt ctatttttca ttgatataaa aaaattattt atatttaaat attgtctata
    45901 tttatacatt atttgtattt atatagcatt tatatttatt tatatttaaa cattatctat
    45961 atctatatag catttatatt tatttacatt taaacattat ctatatttat acatcattta
    46021 tatttataca tcatttatat ttatacatca tttatattta tacattaaaa gaagctgtct
    46081 caaaaaacaa gagacagcaa atcttttagt ttattccaca ttttttgcat cattatttaa
    46141 ccctgtacat tttaactgta aatcataagc tttgttttga aactcagaag ctaagttttc
    46201 agctatagta gctctttcat ttgcttcttc aagttgagta cttaactcct caatcttgtt
    46261 tttataagca tctaactctg ctctagaacc ttctgtcgta ttactaagtt cgaatatttc
    46321 ttgcttttta ttttctataa tctcaattaa ctctttcatc ttagtttcag cttcacgatt
    46381 ttctgcttct ttttctgcta tcgtaagctt taaagacttg atttctaatt gaagctcttc
    46441 attagatgct ccaaccttct tactcaattc ttcattcgct ttaatcaact tctcattctc
    46501 atctgaacat tcaaataaaa ggtctgatat atttaatgca gttaatatcg cagcaactga
    46561 taagctcaat ttcgggtttt gacgtgttat tttatccatt tctttgtcta caaaatcagc
    46621 aatactaatc ataaacttct ctgatttgtc tccaaccatt ggatattcag cgccatggat
    46681 tttaaccatt actttgttca tcctaacctc ccccgacatt agttgttaat ttgatcttaa
    46741 gttagcattt aatttttcgc ttaattcact taatatctta tcatgcacct tagctacatc
    46801 ttcatctgtt agagttttat ctttacttct ataagttatt gaatatgcaa ttgacttgta
    46861 tccagcttct atttgagaac ctttgtaaac atcaaataac ttgtagcttt ctactaatcc
    46921 ttgaccattt tcctttatta tatcttctat ttgttttaca aatacatcat ctttaacaat
    46981 aagagctata tctcttgatg tagatggata ttttggtaat ggcacataat tctttgttct
    47041 atcagaatta tcaaatacaa agtcaatatc tatttcagcg acataaactc tttgacctag
    47101 attgtagttt tctataacat ctggatgcaa ttcacctaat gtacctacat atttattatt
    47161 atacactatt ttagcacatc taccagggtg gaaggtagta ttattatctt gaggttcaat
    47221 ttcataacct ttaaatccga catttacaag tatagtttct atagttcctt ttagtgcaaa
    47281 gaagtcaaca tctttaccat acatacctac acacattcta ttttcttcct taggtaattc
    47341 tgaatcttgt gggatgaata tatgtccaca ctcaaatgca gatacttctt ctattttatg
    47401 agatacatta gttgataaaa catctaacat atttggtatt aaagtagttc tcattacaga
    47461 agtttcttct cctaatgggt taagtaattt aacaaaattt ctctttgcat taccttctgg
    47521 tactcttatc ttatctactc ccttagggct tacaaatgaa tatgttaata tttcatttaa
    47581 tcctacagca gttgaattat cttttaaagc atccatgaat ttttgttttg aagttttaat
    47641 tcctgctgtc gtatttcctt ctaattgtac agaaggtata ttctcaaatc cataaattct
    47701 agctatttct tcccatacat cagcttcttg ttccatatct gttctaaagc ttggtacatc
    47761 tatttctaat ttatcattag ctaccaaatt acatttaaac tctaatgatt ctaaaattcc
    47821 tacaaactgc tccattggta catctacacc taataggtgg ttaattcttt gaggatttac
    47881 taccaatttt ttaggttctg gtttatttgg atatacatct acaacacctt ttaaaacttt
    47941 tcctgctcct aacatttcaa caagttgtgc agctctattt gctgctatct ctgcaagatt
    48001 agggtctaag tctttttcat ttcttgaaga tgcttctgac ctaataccaa cttttttagc
    48061 tgtcattctt atgttttctg gtttgaaatt ggcactttca aaaagtacag tcttcgtatt
    48121 agaagttatt tctgagttag caccacccat tacaccagct aaaccaagtg atttttctcc
    48181 atttgttata actagcatat ctttgtctaa tgttctctca acatcatcta atgttacaag
    48241 tttctctcca tctttagcat ttcttactac tattcttcca gtctctactt gatttatatc
    48301 aaaagcatga agtggttgac caagctctaa cattacgaag tttgttatat cgactatgtt
    48361 acttataggt cttactcctg cttctgtaag tcttctttgc atccaatatg gagaaggttc
    48421 tatttttaca tctgtaacca ttctagcaac atatcttcta cataaatctg gattatctat
    48481 ctcaactttg aaatctatct cttcgtcact ttcttttact tcgatttcag gatattttac
    48541 ttttgttcct atagttgcag ctgcttctct agctataccc atcatgcatt tacaatcagg
    48601 tctgtttgaa gttaattcaa aatctattaa agcatctttt aatcctaaaa catcttttat
    48661 atcttttcct aattcataag aatcttcgtg gtctaaaata tatataccac ctcttttata
    48721 ctcctcaatg taatgttcat ctatacctag ttcagctgct gaacacatca taccatctga
    48781 taattcacct ctgaaatcag tctgtttgat ttcaactcct ccaggtaact tagaaccatt
    48841 tacagctact ggaatataat ctccttctga tatatttgta gctcctgtaa ctatttgaac
    48901 aactttatct ccaatatcta ctttagttac aaccaactta tcagcatttg gatgttgttt
    48961 tatttctaaa atctttccaa ccaatatatt ttctatttct tcaccataat aatctattgt
    49021 ttcaacttta gttcctgtca ttgtcatttt atcagcgaac tcttttacat ccatgtctat
    49081 atcaacatag tctctaagcc attttaaaga tactaacatc tacataccct cctaattaaa
    49141 attgatttaa gaatctcata tcattttcga ataataatct aatatcatct atttcgtatt
    49201 taagcattgc aagtctttca accccaactc caaatgcaaa tccactgtaa acttctgggt
    49261 ctattccaca atttctaagc acatttggat gaaccatacc tgaacctaat atttctatcc
    49321 aaccttcata tttacacatt gggcaacctt taccaccaca tttgaaacaa gtaacatcaa
    49381 cctctgcact tggttctgta aatgggaagt tgtgaggtct aaacttagtt ttgatatcag
    49441 aaccaaacaa tttttcaacg aagatatcca tagttccttt aaattctgcc atagtaacat
    49501 cttttccaac aacaagccct tctatctgat ggaacattgg tgagtgtgta gcatctggcg
    49561 agtctgacct aaaacatcta cctggtgcaa ttacttttat tggtaactct tgacttctca
    49621 tagttcttac ttgaactgga gatgtttgag ttctaagtaa taccccatca ttgatataga
    49681 atgtatcgct catatctctt gatggatggt ctttaggagc gtttaatgcg tcaaagttgt
    49741 tttcaacagt ctcaacttct ggcccttctg ctatagagaa tcccattccg ataaatatat
    49801 ctgttacttc atctataatt tgagttattg gatgcttctt cccaaccttt aaaacttttc
    49861 ctggttgagt aacatctatc acttcctctt ttaattttct ttctttttca atagcattta
    49921 tttcttcttt tttagaattt atgctaagtt caatgttttc tcttacctca ttggcaacct
    49981 taccaactac tggtctttct tcagcagata atttacccat ttctttaagt atggcagtta
    50041 tctcaccttt ttttcctaag tacttaactc ttaaactttc tacactttct atgctttgtg
    50101 cttcttttat ttcagccaaa gctgcttcac gtaaagcaag taatttttct tgcacacata
    50161 tcaccctttc gtttttttgt ataaaaaaag cccctcaatc cctgtctagg gacgaaaggc
    50221 tatagtttcg cggtaccacc ctagtagttt aacaatttaa aaatcatcaa accacctcta
    50281 acaaacttaa cgcgtttttg acgtcaaagc ctactgtaaa atttcagctc tgttactcca
    50341 gagggaactt ctcatgacct cttagaaaac actcccagcc taggtgttta tctctttact
    50401 aagtttaatc aaaatacttt cctctttcat tgcatttaca atattatatt gtttatttta
    50461 gtattatatc atttccattc aaattatgtg actattttta atatatatcc aaatacataa
    50521 ttaatctaat tattttttat ataatatata tctaatgcat aattaact
//
LOCUS       DAEQAF010000016        47838 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.017, whole genome shotgun sequence.
ACCESSION   DAEQAF010000016 DAEQAF010000000
VERSION     DAEQAF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47838
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.017"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            261..449
                     /locus_tag="KRN00_001070"
     CDS             261..449
                     /locus_tag="KRN00_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBH1826937.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            complement(609..761)
                     /locus_tag="KRN00_001071"
     CDS             complement(609..761)
                     /locus_tag="KRN00_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBH1826938.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(859..1335)
                     /locus_tag="KRN00_001072"
     CDS             complement(859..1335)
                     /locus_tag="KRN00_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1826939.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            1554..2315
                     /locus_tag="KRN00_001073"
     CDS             1554..2315
                     /locus_tag="KRN00_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1826940.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLCYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            complement(2575..4503)
                     /locus_tag="KRN00_001074"
     CDS             complement(2575..4503)
                     /locus_tag="KRN00_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1826941.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITISRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQNNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILNEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHNNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            4737..5189
                     /locus_tag="KRN00_001075"
     CDS             4737..5189
                     /locus_tag="KRN00_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1826942.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTNEVKNASDASHLVKYITNKMKEE"
     gene            5192..5500
                     /locus_tag="KRN00_001076"
     CDS             5192..5500
                     /locus_tag="KRN00_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1826943.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            5614..6720
                     /locus_tag="KRN00_001077"
     CDS             5614..6720
                     /locus_tag="KRN00_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1826944.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFMAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENTEFDEIELDIM"
     gene            6795..9473
                     /gene="mngB"
                     /locus_tag="KRN00_001078"
     CDS             6795..9473
                     /gene="mngB"
                     /locus_tag="KRN00_001078"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBH1826945.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRSFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKKARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MIVKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKNLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEYSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(9790..12123)
                     /locus_tag="KRN00_001079"
     CDS             complement(9790..12123)
                     /locus_tag="KRN00_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1826946.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQAGAKGGA
                     KNPFEQESFVGSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKAISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTVTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(12098..12814)
                     /locus_tag="KRN00_001080"
     CDS             complement(12098..12814)
                     /locus_tag="KRN00_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826947.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            complement(13228..13884)
                     /locus_tag="KRN00_001081"
     CDS             complement(13228..13884)
                     /locus_tag="KRN00_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1826948.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILVEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            complement(13939..14568)
                     /locus_tag="KRN00_001082"
     CDS             complement(13939..14568)
                     /locus_tag="KRN00_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1826949.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSEHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            complement(14699..15340)
                     /locus_tag="KRN00_001083"
     CDS             complement(14699..15340)
                     /locus_tag="KRN00_001083"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBH1826950.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            complement(15349..16020)
                     /locus_tag="KRN00_001084"
     CDS             complement(15349..16020)
                     /locus_tag="KRN00_001084"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH1826951.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANVIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            complement(16025..16909)
                     /gene="rsgA"
                     /locus_tag="KRN00_001085"
     CDS             complement(16025..16909)
                     /gene="rsgA"
                     /locus_tag="KRN00_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH1826952.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDENEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLALEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            complement(17007..17744)
                     /locus_tag="KRN00_001086"
     CDS             complement(17007..17744)
                     /locus_tag="KRN00_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1826953.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKADISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            complement(17852..19861)
                     /gene="pknB"
                     /locus_tag="KRN00_001087"
     CDS             complement(17852..19861)
                     /gene="pknB"
                     /locus_tag="KRN00_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBH1826954.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQVFL
                     AYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCIISQ
                     TPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYEYS
                     SIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNTPT
                     EPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSSGG
                     SNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            complement(19878..20630)
                     /locus_tag="KRN00_001088"
     CDS             complement(19878..20630)
                     /locus_tag="KRN00_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBH1826955.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            complement(20650..21681)
                     /gene="rlmN"
                     /locus_tag="KRN00_001089"
     CDS             complement(20650..21681)
                     /gene="rlmN"
                     /locus_tag="KRN00_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBH1826956.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            complement(21689..23014)
                     /gene="rsmB"
                     /locus_tag="KRN00_001090"
     CDS             complement(21689..23014)
                     /gene="rsmB"
                     /locus_tag="KRN00_001090"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBH1826957.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFVLDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQDVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            complement(23076..23777)
                     /locus_tag="KRN00_001091"
     CDS             complement(23076..23777)
                     /locus_tag="KRN00_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBH1826958.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            complement(23846..24598)
                     /locus_tag="KRN00_001092"
     CDS             complement(23846..24598)
                     /locus_tag="KRN00_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBH1826959.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            complement(24608..25537)
                     /locus_tag="KRN00_001093"
     CDS             complement(24608..25537)
                     /locus_tag="KRN00_001093"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBH1826960.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            complement(25552..25992)
                     /gene="def"
                     /locus_tag="KRN00_001094"
     CDS             complement(25552..25992)
                     /gene="def"
                     /locus_tag="KRN00_001094"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH1826961.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEELIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            complement(26010..28535)
                     /gene="priA"
                     /locus_tag="KRN00_001095"
     CDS             complement(26010..28535)
                     /gene="priA"
                     /locus_tag="KRN00_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBH1826962.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVPFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNNIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKGRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            complement(28774..29973)
                     /gene="coaBC"
                     /locus_tag="KRN00_001096"
     CDS             complement(28774..29973)
                     /gene="coaBC"
                     /locus_tag="KRN00_001096"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBH1826963.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            complement(29978..30244)
                     /locus_tag="KRN00_001097"
     CDS             complement(29978..30244)
                     /locus_tag="KRN00_001097"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBH1826964.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            complement(30247..30864)
                     /gene="gmk"
                     /locus_tag="KRN00_001098"
     CDS             complement(30247..30864)
                     /gene="gmk"
                     /locus_tag="KRN00_001098"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBH1826965.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLEELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            complement(30894..31775)
                     /locus_tag="KRN00_001099"
     CDS             complement(30894..31775)
                     /locus_tag="KRN00_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBH1826966.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            complement(31779..32609)
                     /locus_tag="KRN00_001100"
     CDS             complement(31779..32609)
                     /locus_tag="KRN00_001100"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBH1826967.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKINLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            complement(32896..33930)
                     /gene="ltaE"
                     /locus_tag="KRN00_001101"
     CDS             complement(32896..33930)
                     /gene="ltaE"
                     /locus_tag="KRN00_001101"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBH1826968.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALTLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVS"
     gene            34226..36001
                     /locus_tag="KRN00_001102"
     CDS             34226..36001
                     /locus_tag="KRN00_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBH1826969.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDALHKVFCNLFNDINSNKYSPCIIIDKKVDRVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            complement(36216..37868)
                     /locus_tag="KRN00_001103"
     CDS             complement(36216..37868)
                     /locus_tag="KRN00_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HBH1826970.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCGHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     IQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENQIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(38167..39378)
                     /locus_tag="KRN00_001104"
     CDS             complement(38167..39378)
                     /locus_tag="KRN00_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBH1826971.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISVGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            complement(39662..40195)
                     /gene="pyrR"
                     /locus_tag="KRN00_001105"
     CDS             complement(39662..40195)
                     /gene="pyrR"
                     /locus_tag="KRN00_001105"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBH1826972.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            complement(40555..41502)
                     /locus_tag="KRN00_001106"
     CDS             complement(40555..41502)
                     /locus_tag="KRN00_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1826973.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALSINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            complement(41471..41917)
                     /gene="lspA"
                     /locus_tag="KRN00_001107"
     CDS             complement(41471..41917)
                     /gene="lspA"
                     /locus_tag="KRN00_001107"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBH1826974.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            complement(42227..43006)
                     /locus_tag="KRN00_001108"
     CDS             complement(42227..43006)
                     /locus_tag="KRN00_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1826975.1"
                     /translation="MKKIIWGICICLLSVVGVYTYSHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            complement(43061..43543)
                     /locus_tag="KRN00_001109"
     CDS             complement(43061..43543)
                     /locus_tag="KRN00_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBH1826976.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            complement(43809..45230)
                     /locus_tag="KRN00_001110"
     CDS             complement(43809..45230)
                     /locus_tag="KRN00_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH1826977.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKEQNNHKLAS"
     gene            complement(45376..46146)
                     /locus_tag="KRN00_001111"
     CDS             complement(45376..46146)
                     /locus_tag="KRN00_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1826978.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELSNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            complement(46151..47353)
                     /locus_tag="KRN00_001112"
     CDS             complement(46151..47353)
                     /locus_tag="KRN00_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1826979.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
BASE COUNT        15966 a         8169 c         5169 g        18534 t
ORIGIN      
        1 taaatatggt ataatttaaa cctagaaaag tttttggata aaatttcttc tatagtatat
       61 atattcaaag aaaaataata attattttcc aaatatattt actttatata aaattatata
      121 tataatttta tatgataata agaaattctt caatatgtgt aaggcaaata tatatttcta
      181 ttgcaaattt ttgttattta tgataatata aatatgtttt tagtctttaa atagttatca
      241 ttttaaggag gtgtgcgtag atggcaaaag tatgtagcgt atgtggtaaa ggtaaggttt
      301 ctggaaacca agtatcacac tcaaataaac ataataaaag aacatggtca gctaacttaa
      361 gaagcgtaag agcgattata gatggagctc ctaagagagt aaaagtttgt actagatgtt
      421 tacgttctgg taaaattgaa agagcttagt aaccacgttt aaaagcctac ttccgtaagt
      481 aggcttttta atttaatcat ttttactctt tctcataaat tttaggatta tacttgaaat
      541 ccattttggt aattttattg ttactacttt catcaatact caccccacac tttatagtta
      601 aaactatttt aacaaaaaaa taataatgct ccacatccaa taagtattaa tgcggtaagt
      661 gctgaccaaa tccagccagg aagcaacatt gacagaatta cagccattcc tgttgctaga
      721 caaagtattc ctagcaatac cttagacttg ttatttctca tggaacacct ccacatagaa
      781 cctgtatcta taaatatttt catattcaag tttatgcgac agttttccat tttagaccaa
      841 taaacacatt atgtaatttt aatttttcat actagaatta ttactgaact ccgatataga
      901 ttctacaata tccaaaattc ctttttttct acttaacctt tcaggtccac tatataaaac
      961 aactggtata actttaggaa gtttaaaatt tttatcttct atttcttcaa gacttttttt
     1021 cataataaaa cttttccaaa tttgttctct atacgatttc aatcttggga caatttcagt
     1081 atccatttct gtttgaaatt ctaacactat ataatgtgat actttgccac ttttagaaaa
     1141 taccttataa attatatcaa cttcttttcc tttatattca catataaaag atgtttctaa
     1201 ctctatattt ttaagagtta attcttttgc tattgagaca cttgtaaaat tttgaatcaa
     1261 acttaaaaaa ctttctttat ctgaatacat tcttctgtac tcttctcgtt tttcattgct
     1321 tctttttaaa ttcatacagt tcctcctaga ctatagaccc tctatttttt agtaaagata
     1381 gtctataaat tttatttttt aattttcatt agtgagtatt gacagttgtg tgtaaaatat
     1441 ccagtaaaga tattttttta tatttttatt aaaagatata aatttttata ttttaatgta
     1501 ttgacattta cgttgcgtaa aagtgtatat ttaatttata ggaggtacta cttatggaat
     1561 atacagttca aaaattaagt aaactagctg gtataagtac tagaacactt agatattatg
     1621 atgaaatagg tcttcttaaa ccacttaaaa taaattcttc aggttatcgt atatatggtc
     1681 aaaatgaagt taataaactt caacaaatac ttttttatag agaattagga attaacttag
     1741 aaaatataaa aaacattata aattcaccaa acttcgatag tttaagtgcg ttaaaagaac
     1801 accataataa attactagcc aaaagaaagc aaattgattt actaatagaa aatgtaacta
     1861 aaactatagc tctgaaggag ggaaaataca ctatgacaga tatagaaaaa tttgaaggtt
     1921 ttaaagaaaa gatgattgat gaaaatgaaa aaaattatgg aactgaaatt agagagaaat
     1981 atggtaaaga tattatagat acatcaaata aaaaacttaa aaatatgtct aagcaagatt
     2041 atgaaaattg gcaaaaccta aatatcgaaa taattagtaa acttaaaaaa gcttttaaaa
     2101 ctggtgatgc ctctagtgaa ctggctcagg aagttgcaaa attacatcat aaatggttgt
     2161 gttacacttg gaacacatac tctaaagaag ctcattcctc tctagcacag atgtatgtat
     2221 atgatgaacg ttttacatca tattatgata gagaacaacc tggattagct aagtttttaa
     2281 gggatgctat agtaatatat acaagagata aataatataa aataataaag gtggtgtctc
     2341 aaaatgaact ttttagttca tgagacactc ttttttgtat gaaatcaaat atatttttat
     2401 cattttatca atgaaaaaca ggtttctctc tctattttga gacagaatct ttattgtata
     2461 ataattataa tcaatacaaa ataataacaa attatataaa acttacttat actatttatg
     2521 ctaaaaacaa aaaatatttt attaaagttt ttaaaactta tgtaatataa aaatctatac
     2581 tatagacttg attatggaaa gaaaattatc aaaatcatta caattagata tactatctct
     2641 aatatcattg ttatgaatta tctttaaaag gatatcataa atggagttta tttttatata
     2701 atcatcttta tttatagcca acatcatgat taatttaaca gtagaatctt cactccaata
     2761 tattggttca ttcaatatgg aaatacaaat cttagttctt atagagctta attccatagg
     2821 atgaggtata gctaaaaaat catctatatt ggtagaagat aaactttctc tgtaaaatac
     2881 agattcagca aatgatggaa atacaatttc actttgagtt aatttgttgc acatcaactt
     2941 tataagctca tctttatctt tgattttagg attaacaata aataaatttt tatcaaagaa
     3001 attgtccaaa agattactat aaatatggga attattagtg attgacttag atatattctc
     3061 tatatctttt tttaatagtt ttaaatccac taatacaata ggaatactat catgatttaa
     3121 aggaattgtc gatattatta tatctacatc tgacaattca ctagctaaaa attgattaaa
     3181 tgatagacat tgaagtatat ttattttatc atgaaaaact ttgtttaatt gaacctctaa
     3241 taacctactt gaaccatacc ctgaaccaca tactaatact acgtttttac acttaatatt
     3301 attttgaaaa aatctctcta ttccagcacc tatatgcagg gatacatatc caatttcatc
     3361 ttctgttaaa gagtaaatac tatttttaaa aactttttct atagcattta aagttatttc
     3421 aaatgctaaa ggataattac tctttattgt atttataagg ggattcacct tatttaaatt
     3481 ataagattta gaattgagaa ttgatttaaa gtgcagtact aaatcatcaa ataatacact
     3541 atcatttcta aggtcaaaag tatattgatt gttgattact tctaaaattt cttcaacata
     3601 ctctataatt ttagtatcta ccctattgga aacgttatcc aaaagagaac ttttagttat
     3661 aaaatgatta tatagataaa ctctgtctgc ctttgaaata attatagtat atttactctc
     3721 aatataatta aatatatttt caacagttgt attcgattga aaatctgtta aaacaacatc
     3781 taaaacatta tctaagcagt aaccatcaag tattctactt atagtaatag ctaaatggat
     3841 aataaagttt tttagattaa aatctaagaa attgatatta aatttattaa tttcacttaa
     3901 cactaccctt tgaagctcta ttaaatctac attattaaat aattctattt ctctatctgt
     3961 aattccaatt atatagtttt caaaattcct atttatcata ttattagaaa tacatcttcg
     4021 aatatctatt tccttacctt caactttaac tccataatat ggcttagaaa ctaatattaa
     4081 attatacttt gacaaaatag gctttattct ttttatgtca tttagtattg taaatttact
     4141 cacatacaag ctattagcta aatcttctag ttttatatat gtattgttat agagaatata
     4201 ttttaaaata tattgatttc tttctatagg agaatctggt atttcacttg aatccataat
     4261 atcatcagat attaatgcta gatactgttg gtataatgct aaattaagaa tatctatata
     4321 atatccttct ccttttttta ttttaataat agcaccattt ttctctaaag ttccatttat
     4381 agaagtaata tcatttctta tagttctctc actcactttt aaatgattac ttaaagtttt
     4441 acaagtaatt ttatcatcac tttcatttaa taatttaaac aacgtgagca atctcttgtg
     4501 cataaatatc cccccttata gaatttcttc taaattatac tatttacact catataatac
     4561 aattactcta ataaaattgt attataataa tttatttcca cttctatatg gaaattagtt
     4621 attatcataa tataaatttc catgtcgaag tggaaattag ttatatttaa tttaattagg
     4681 ataatgatta caatataaat ataagttaag acattatgaa tggagtggaa aaatatatgg
     4741 tactacaaga aaaatatata tttatagata aagacttaaa aagcaaagaa gaagtattaa
     4801 attttattgc agatagtgct tatatactag gtattacaac taataaagag gctcttttaa
     4861 aagaccttct aaaaagagaa aatgaatttc caacaggaat aaaagatgga tttgcgatac
     4921 ctcatacaaa aagtgtaaat gtaaaggaag cttccatact ctatattaaa acaactaacg
     4981 agttagagtg gaaaacttta gatgatagta aggttagata tgtatttagt ttgttagccc
     5041 cacataaaaa tgaaggaaat atacatttga aaactctatc taaattagcc acatgtttaa
     5101 tggaggatga ttttacaaat gaagttaaaa atgctagtga tgcaagtcat ttagtaaaat
     5161 atataactaa taaaatgaag gaggaataat tatgaaaata gtagcaataa catcatgtat
     5221 agcaggatta gcacacacac ctatggcagc aaaagcttta gaacaagctg catcaaaaat
     5281 gggtcatgaa atcaaagtag aacaacaagg tgctatggga cgagtaaata ctataacaaa
     5341 agaagaagca caagatgcgg actttatact tatagcatct gaccaaacta tatctggaat
     5401 ggaaagattt gatggtaaaa aagtgataaa agtcaaaata ggtatagcgt taaaaaaacc
     5461 agaagctgtc ttaacaaagt gtatagaagc tatttcttaa taaaaaaatc tcactctaat
     5521 atagaatgat aaaaatcaaa aattaaaaaa ttgtctaatg taattataac atattatcaa
     5581 aaaatataac aaacttatat aggaggatta aaaatgagta aaaaaaataa atctctttta
     5641 agtgaactta agggacactt aatgacaggt atctcatata tgttgccact tgtaataggc
     5701 tcatctttag ttgtagctat cccaaagctt acagctttag cagtgggtat aacaagttta
     5761 gatgcttata aaaatgtatc tggtttttat catattcttt acttaatgga acaagttggt
     5821 tggactggca taggtctatt aaatacggta ttagcaggat ttatggcatt ttcaataggt
     5881 gagaaaccag ctatgggtgc aggttttatt ggtgggctca tagcaagtaa tactaatgca
     5941 ggattcttag gagcagtaat agcaggtttc tttgctgggt atgtttgtaa gtttttaaag
     6001 aaaaaaatta aaatatctgg gtcagcatca ggaatgatgc cacttataat aatgccactt
     6061 ataacagttg gattaactgg ttttttaatg agtgttgtat tagcaggacc tttaggaaac
     6121 ataaatactt cattaaatgc ttgggtagct gaaatgtgtc aaaatggaac aaattcggtg
     6181 gtattggctt taattttagg cgcaatgata ggattcgatt taggtggacc agtaaataaa
     6241 gcagcttgga tggcaggaaa tgcattattg ttagagggaa tctatctacc agcaatattg
     6301 gtaaactgcg caatagttat acctccacta ggatatggtt tagctacatt cataagaaaa
     6361 tcaaagtttt ccaatgcatt agctgaaaca ggaaaaggca atatagttat gggtataatt
     6421 ggaataacag aaggtgcaat tcctttcact ttaacaaatc cattaaaatt agttcctgtt
     6481 aatatgatag gatgcgcttt gggtgtagga ttatcagctt tgttaggtgt acatgctata
     6541 atgcctccag ttggtggatt atatggattt atatcaatag gttctggatg ggcttactta
     6601 gtaggtgcaa tatttggagc tttagtaata gcaatattat caacaacttt agtagacttc
     6661 aatgaagatg aaactacgga aaatacagaa tttgatgaaa tagagttaga tataatgtaa
     6721 attaaaaact taattttaga taattgagaa ttgagtgtac tctcaattct caattaaatt
     6781 ttgggaggat ttttatgaaa aagacaaaag tacatgtagt tccacacagt cattgggata
     6841 gagaatggta ttttacaaca tcaaggtcaa aaatatattt aatgaaagat tttcaagata
     6901 tattagacat attggaagaa aaagaagact ttaaatactt tactatggat gcacaagctt
     6961 ctctcttaga tgattattta aaatggagac ctcaggatga atatagaata agagatttag
     7021 ttcaaagaag aagattagtt attggacctt ggtatactca aacagaccaa ttggttatat
     7081 caggagaatc tataattaga aacctttact atggaataga tagatgcaat gaatttggtg
     7141 aacctatgag ggttggatat gtaccagatt cttttgggca atcagctcaa atgccacaaa
     7201 tatacagaag ttttggaata gatagttcat tattttggcg tggagtttct gatgatatgg
     7261 tagatacaac agagtttata tggaaaggtt ctgatggttc aaaagtatta gcagttcaaa
     7321 taccatttgg ttattactat ggaggtaata taccagaaga tgattcagat ttaaaagaat
     7381 atttaaaaga tataatcgga aaacttaagg ttaaagcttc tactaataac gtatattttc
     7441 caaatggatt tgaccaagca ccaataagaa aaaaccttcc tgatatatta aaaaaagcta
     7501 atgaaataga taatgaaaat gaatacgaaa taagtgatat agaaaactat atagattcag
     7561 taagaaatga aagaaatgaa tttacagagc ttaaaggtga atttttaaat gctaaacata
     7621 tgagaataca caaatccata ttctcctcaa ggtcagacct taaaataatg aataacaaat
     7681 tagaaaatta tatcacaaat gtacttgaac cattattaac attaagttat tcacttggaa
     7741 atgaataccc tcatctagtt ataaaagata tatggaaact tatgtttgaa aatgcagctc
     7801 atgacagcat aggttcttgt aatagtgaca caacaaatga ggatgtatac acaagataca
     7861 aaaaagccag agatttgagt ataaatttat tagatttgca tatgagactt ataagtactc
     7921 aaatcaaaaa taataatgaa gaaataacat taacagtatt caatggattc ccagaagtca
     7981 gaaatgaagt tgtagaattt gatacttata ttccaggtca agattttgtg ataaagaata
     8041 aaaatggaga aattcttaat tatataataa aagaaaaaga agatattaca aattatatat
     8101 taactcaaac aataagatta aacccaagta aaaaaatata tatacccaaa actgtatata
     8161 gagcaaaaat tgcactttca gtaaaagata taccaccaat gggatatact caactagttt
     8221 ttgaattgga tactaaaaat aaatgtgaaa tagaaacaag taattgcaaa gaaatagaaa
     8281 acaaatacta caaaataaca gccaataaaa atggttcatt agaaatatta gataaagaat
     8341 ctaataagac ttataaaaac caagctgtaa ttgaagacaa tggagatgat ggagattcat
     8401 acaactattc tcctccaaga aaagatattt atgtttcatc tttagattct gtatcttcag
     8461 tagaagtgct aaaatcaaac attcaagaag aaatgatagt taaatattca ttgaccatac
     8521 cagcttcact ggaagaaagg gctataggta aagtttctgt gaaaatgcca gtaacaatga
     8581 aaatcacctt agaacctaaa gaacaaataa ttaagtttaa tgttaatata aaaaataacc
     8641 aagcactatc tcatagagta agagttttat ttaatacaga aatagcatct aagttttcta
     8701 tagcagatca acaatttgga ataatacaaa gaccaacagt attagaaaaa aaccttgcat
     8761 tatggaaaag agacaattac tcatggcaag aaaaacctat aactatcgaa ccaatgcaaa
     8821 gttttgttac tttagaggat ggacaaagag gaatagcatt aataactggt tgtgtaagag
     8881 aatatcaaat agttggtgat aatttagata caatagcatt aacactattc aggtcatttg
     8941 gatatatggg aagagaaaat ttactttata gaccaggaag agcttctgga gaaaaaataa
     9001 tagcaacacc agatgcacaa ttacttaaag agttaaactt tgactttggt ctttacatat
     9061 ataacaataa atttgatgaa gcaaatgtag ctaatacagc taagagattc ttaacaccta
     9121 tacaaatata tgagtatgct gattttttaa atggtagact tatatttgca ttcaatgacg
     9181 aaaaacaaat atatgaaaat gaatatagtt tgatgaatgt aaataattca aatttcacag
     9241 taagtgcaat aaagaaagaa gaaaaaggag atggaattgt agttagaatc ttcaatggta
     9301 tgaaaaatga ggatgctaag ggaagtctta acatcaataa aaatgtcaat gatgcttata
     9361 gtgcaatgct cgacgaaatc tatgataata ctagcaagct taaagtaaat actaaaactg
     9421 tagaggtaaa ttctttatca cattgtaaag tacaaacaat agtaattaaa taatataaaa
     9481 tagattatac aagatttcaa aataaattgc tagtactatg ttaatagtaa acccagatat
     9541 tatgctattt ataagctctg taacactaaa taacattttg taaaataaaa aggtgaacct
     9601 tgtatattag gattcacctt ttttaaataa atcaacattc tgttttaaaa taacatttat
     9661 aagctgtttt gaaataatgc ttacaaatta ttttaaaaca atacctataa atttttattt
     9721 aaagaataca cataaatatt tccagactct tttattctat agactttata attattaaat
     9781 aagtctaatc taatttttgt taaaagtaat tgtaacttta aataaatcac catccacact
     9841 tatattcatc ttaccaccct gtaattctat aaaacttttt gctatcgcta aaccaagacc
     9901 agaaccttct gtgttacgtg atttatctcc tcttacaaat ctctccatta tatcatctac
     9961 actaaaatca atctcagatg cagacatatt tttaagcata atatttactt tattatctgt
    10021 ttctaaaata tcaatataca ctcttgaatt tggcattgca tatttgctta tatttattat
    10081 aagattttca aatactctaa atgtacgctg actatctaat ggtaatatta ttttttcatt
    10141 agaaaagtta ttctttacta ttagagatga atctgcaagt ttgtcatcta attctaaaag
    10201 tgtctgcttc attagagata caatatccac atttactata ttcaaataaa catctccact
    10261 atttgccttg cttacttcaa acaaatcttc tattagatgt tgcaatcttt gtgactttct
    10321 gtctaatgta tcaatataca acttacgatt ttcatctgtt atactttcat cttttaataa
    10381 atctatataa gtgattatag atgttagagg tgtttttaag tcatgtgata catttgatat
    10441 aagctctgtt ttcatctttt gactcttaac ctcttcgtca acagcttttt taaatccagt
    10501 ttgaatattt cctaattcgt cttttatagg attaaaaaat cctaaatctt tttccatatt
    10561 tacatctaag tttccatctg aaattttctt tgtaacatct aaaagttgat tatattcata
    10621 tattgtcttt ttagagtaat ctgacagtat cttaaataat actactgaat atattaatgc
    10681 gagtattatt ccaaagaacc acatactaca cattataact ataatcaata aatttattcc
    10741 caaaattgta actatagttt tatttggctt ttcttttaga tttattgttc taatttgatt
    10801 aataactgtt tttcctgctt tttttagcca tacaaaaaac attcctgtca cagtatgttt
    10861 tgtaaaatac tctcttattc caacatttaa aatatgtttt aaaagtatta taaatacaaa
    10921 tattattgag aatattacaa accaataagt taaattcatt aaacttacca atatactagc
    10981 cattttagca cttatgtcat tgtttataag gtactctaca taattcccac tcaaggtatt
    11041 acttattata acagtaggat ataaatctac aagcccctgt ataatagcaa gagcaataaa
    11101 gagtatctct aacggtattc ttgataatgt atcaaatcct agcaactctt tagattttct
    11161 atatgggaat gctaaagcta caataacaac tatagctaat ataattttta aaatcattcc
    11221 agaaatctta taataagaat tattttctac attgcttata tatgaaatta taccatcatc
    11281 aaaataagta tttccataac catactctac actatcacct ttacttattg ctttaggtac
    11341 agcatatact aatgttatat tttttattgg agataactta tatgaaattg aatttcctcc
    11401 taaacttgta tccattaaat cttctcttgc tttagataac aacatttgat taataacttt
    11461 ttgatttact ccataagaat ccacaatatt tacttttcca tctttatcaa aattcattac
    11521 aacgtagaat ctatagtttt cttttatatc tgtaatctgc ttttgtcttt cctcatcatt
    11581 catttctgta ttttttgact gattttcatc agaattttct tttgaagcat cattctttgt
    11641 tgtatcaagt actcctaatt ctttattatc attaaaaaat tcaaaattgc tttctttatc
    11701 aactaaatag tactttaaat tctttcctga cgctttaatg aaatgctccc aattttcaaa
    11761 gttttcatta aaatctgcat taatactatc atctgtatag taagtttctg aaccatcata
    11821 agtatctttt tctttactta cattttttat atagttcata gtttcttcat tgataaatag
    11881 ctttgatggt tgtatcatct taccttcttg ttcttccttc atattatgat ataaaacata
    11941 acttccttta tatatactac ctacaaagct ttcctgttca aatggattct ttgctccacc
    12001 tttagcacct gcttgtatag tagaatattg actaatcata cctaatgatg ctgataacat
    12061 aagtataaaa actataatag taactatata tttatcttta aattttttca attttgtatc
    12121 caacacccca caccaccttt aaatatttag gattttttgg gtcaatctct atcttttccc
    12181 ttatattcct cacatgtacc ataactgtat ctgtatttac agcattctca ttccaaactc
    12241 tttcatatat ttcatcagca gaaaaaactc ttcctgcatt tctcataagt aaacttagta
    12301 ttttaaattc tataggagtt gtttttatat actttccatc aatactaact tcttttgtat
    12361 tttcatttaa ttctaatccg cctattgcaa acacactatc gtcactttct accttttgct
    12421 ctttatttcc aaccatgttt agatacttag tgtaccttct aagttgtgaa ttaactctag
    12481 ccaatagttc taatggctta aaaggttttg ttacataatc gtctgctcct atattaagcc
    12541 ccattatttt gtcaacttcc tctgattttg cagatagcat tattactgga aaattatagt
    12601 tttctctaag cttcattgta agtgttatac catccatttt aggcatcatt atatcaacta
    12661 tagctaaatg tatttcttgg ttttctataa ccttaagacc ttctaatcca ttgtatccct
    12721 taaaaacatt atatccttga tttaatagat atatttctat agcatctgct atctcctttt
    12781 catcttctac caccaaaata ttatatgaat tcattctaat ctcctttata ttaatttata
    12841 aattttcttt acatatatga ttatacaata tgatagaagt ttttccattt atatatatat
    12901 ttatatcttt tgttctggtt atttgtattt aatgtccatc ttagaaacct ccttctagtt
    12961 taaatttaat attttttcat tttgttttat atacttaata ttaaacttaa aaacttaaga
    13021 tattacatat acttttctaa agattttcta aagatttaaa tatatttaaa attaatatac
    13081 aaaaaaagta gttcttattg tattaattaa atcaatgatt tgaaatataa aattaatatc
    13141 aataaaacct actttttaat tttttaaata tttattttta atttattttg tttttaattt
    13201 acttcgattt taaaatgtcc ttgactttta ttttataaat gtacatattt cttctactgg
    13261 ttttttagat ggactcttca aattgtcctc tggcactcca agagctaaca ttgcacctaa
    13321 aaaatactct cccttttcaa aaccagtttc tgcttctaaa acagcttcta tctcatctgc
    13381 tgcatagttt tgacttgtca accaacaaga accatatcca agttcaattg ctgatagtgt
    13441 aaagttttca attgcagcac ctagactctg catacctgga tttcttataa ataatttatc
    13501 tatagtctcc ttaggtgcat ctataagctc taattcataa tatcctgatg gattatatac
    13561 ctttgtaaaa actaatacta aaactggagc ttttaagtaa aatagtgtaa aatttttaac
    13621 aaattttcta aatctattag ccttatccac tgatacttta tccatttcta caagtatttc
    13681 ttgttgcttt ttagttatca catctgctat cttttccatt aaatcacggc gttttataac
    13741 aacaaaatgc cagttttgaa tattcttgcc tgatggtgct gcacctgctg cttttatcat
    13801 ttttaaaata tcttcatctg atacatcttg atttttaaac tttcttacac tttgtctttt
    13861 aaaaatagta tcttgtaatt ccatttttaa atccccccat aactttttta ttattttaat
    13921 ataattttta aactcatctt attttaatat atcatgttct aacaaatctt taaatgaatc
    13981 tataaaataa tcatatacat ctacattccc aaacccatat ttggcatata taaaaggtat
    14041 acctacaaac ttagcactat ttgcatcacc ttgcgtatca ccaacataga ttggatttat
    14101 taatttattt ctttcaatta taagtttatt attttctcct ttatgcaaac cagtattacc
    14161 aggacattca aaatctataa aatactgttc tagtttatgt gcttttaaaa aagattctat
    14221 atatccagct tgacaattac ttactataaa taatttatat tttttagata gtaatttaag
    14281 agtatcttct atatcatcaa ataatttagc tccattttca gataaatagt cacattcttt
    14341 caaagaacat tcattcaata aattcattct ttcttcttca cttaaatttg gaaataaacg
    14401 atttgctatt tcctcaaaag aaagccccat aagacttcta aataaatctt ttgtgacact
    14461 taattctatt tccttatgct cacttaaaac atcctgccag actttgcata cttcttcagt
    14521 tgaatcccac aatgttccat ctaaatcaaa aataatacta tctaccacaa aaaatccccc
    14581 ttatgtcaaa gtttattata tatttataat tatatactaa aaagcagata caatcataaa
    14641 tatattttac ttgattgtat ctgctctaca atataaaacc aattgtcaaa atcaaatttt
    14701 ataaatttct aactacaagt acacagcctt gctctacttt aatcttacaa gaattactca
    14761 acataacatt tgatattcca ataggtacag agtatttcat ataataatta tcgagagggt
    14821 attctaagcc agtaagtgtt acacccttag catcaccatt tatagctatt acagaaatag
    14881 tgtcccctgg gtttccatac aatgaaattt cctcattttc aactatatac atctcttctt
    14941 tatcagaaag tatcctagaa tatataccat cttcttttaa ataatataat agctttatat
    15001 ttgcaagagt gtggtcaatc cttcccccta aagcaccaaa aaaatcaata tgatttgctt
    15061 taagtgtctt agctaaaaaa agacaaagct ctgtatcagt ctcatctttt ttagatggaa
    15121 atttttcaaa tttaacacct ttatttttat agaagtttat cttttcttct tctactgaat
    15181 ctaaatctcc taatatataa tctggcatta tttccatttt ataagtgtga tttgcccctc
    15241 catctgcaca tattatgcag tcataacatt ccttaattat aatatctctt gtaacttcgt
    15301 aatcttcaat ttcgccattt aaaacaatac agattttcat tattaaattt aaactaattc
    15361 ttcaagagaa gcattctttc taaataaatt aactgtttct tgaatgtcat cacttccaaa
    15421 tattgcagaa cctgctacta ttacattagc tcctgcttgt acaacttcgg ctacgttttt
    15481 agggcttata ccaccatcaa cttctatatc aatgtttaat ccttgactat ctataatagc
    15541 ttttaactct ttaatcttat ctaaaacaca aggaataaat gattgtcctc caaatccagg
    15601 gttaacagac attaataata ccatatctaa atcaggtagt acatgtttaa tcgtatctac
    15661 tggtgtagct ggattaagta ctacaccagc ttttattcca tgtgatttta tattttgtat
    15721 agttctatgt agatgaacac aagcctcctg gtgaacagtt attatatcac atcctgcttt
    15781 tacaaattct tcaatatact ggtctggatt ttctatcata agatgagcat caaataccat
    15841 atttatattt tctttcttta aacttttgac tacaagtggt cctaatgtaa tgtttggtac
    15901 aaagtgtcca tccattacat cgatatgaag atattcacat cctgcacttt ctacttttct
    15961 tacatcttct aataattttg caaaatctgc tgataatatt gatggtgcta atttaatcat
    16021 gtttctaata cctcctacta ttattttgtc ttatttcatg tagcagctgt atataactat
    16081 catatctttc tttagatatt tctccatttg taacagcttc ttttatagca caattaggtt
    16141 cattttcatg aatacacttt gaaccaaact tacaatcatt aaatttatca aattctataa
    16201 aataatcttt aagttcaact tcctctatat cttcaagggc aagggaacta aaacctggtg
    16261 tatctgcaac cattccacca aattctaatt ttaaaagttc agcgtgacga gtagtatgtt
    16321 ttcccctttt tattttatca cttacaactc ctgtttgaag tttaaaattt tcatctattt
    16381 catttaataa gcttgatttt ccaactccag atggtcctgc aaacactact acattttctt
    16441 ttaattcttc ttttacttta tctatattta acttagtaat attgcttaca ggaatgactt
    16501 tatagccact aagttcatat atatttttaa cagtttctaa tgtatcatta tcatctaaat
    16561 ctgcttttgt aaggattatt acagtttcta aattttcttt ttctgccaaa actataaatc
    16621 tatctaaaag agataagttt ggtttaggat tttttattgc gaatactatt aatgctttat
    16681 ctacatttgc aataggaggt cttataagtt ctgtatctct actgtcgatt tcttctaaga
    16741 tacccttttt ttcattttca tcaacaatgc ttattttgac tctatcacca accaaaggtg
    16801 ttattttctg ctttctaaat atccctctag ccttacattc ataaatacca ttataagtat
    16861 ctacataata aaatccacta atccccttta taatttttcc ttctagcatc aaatgcctcc
    16921 ctttataaaa tttatataaa cacatactgt ttatgagtag tatatcgtgt tattctttcc
    16981 tatttttata taataccaca ttttttttaa ataacaaatc ctccgtttgg actaattacc
    17041 tgaccagtga taaaatttga tttgtctgat gccaagaaaa tagcacaatt tgctatatct
    17101 tctggagttc ctagcctcat tagaggggtt tcttccacaa gagcgtctat atcttcctca
    17161 ttatatccag ataacatgtc agtattaatg acacctggag ctatgctatt tactctaata
    17221 tttgatggtc ctacttcttt agctaatgcc tttgtcatac ctattatgcc tgcttttgtt
    17281 atagaataat gcacttcaca agaggcacct gatatacccc agattgaaga tatattaatt
    17341 atatttcctt ttttttctga tatcatgtat tttaaagcaa cttgtgaaca ataaaagctt
    17401 ccttttaaat taatattcat catattatcc caatcttcat cagttatatc tgtaaacaac
    17461 ttatcttgac ttacaccagc attgtttaca agtacatcca atcctccaaa ttcttttata
    17521 caataatcta ccatatcctc tacatcttct ctatttgaaa tatcagcctt aaaaagtttt
    17581 acagaaaaat ttttttcatt taatatagtg tacaactctt tagcttcatt ttctgactta
    17641 ttaaaattta ctaatacatt gtaaccttct tttgcaaaag ctttagacat agctttacca
    17701 atccctctag ctcctcctgt aattaaaact gttttcttct tcataaatac ttttctcctt
    17761 atattataac caattcagta ttttatacaa aacaaactgc cctttaaaga aaatattttc
    17821 tataaaagga cagctcttat tttattaata tttattctgt tttaccaatg tttgcgccag
    17881 ttcctgatga agttcctcca ttatctcctg agtttgagcc tcctgaacta tctccattgt
    17941 ctcctgagtt tgaacctcct gaacttcctc cattgtctcc tgagtttgag cctcctgaac
    18001 ttcctccatt atctcctgag tttgagcctc ctgagtttcc accactattt cctgagtttg
    18061 aacctcctga gttacttcca ttattgcctg agtttccacc actatttcct gaatttgagc
    18121 ctcctgaatt tccaccactg tttcctgagt ttgaaccagg ttctgttggt gtattattct
    18181 ctggtgttgt tggtttttta tctggtactg ttggagtctg tgtatttgat ttttctgaac
    18241 ctttgcttac atataggttt acctcatcac cttcctgagc tcttgatgag ccagcacccg
    18301 gactctgact taaaactgta ccttctttat atattgagct gtattcatac ttaacagttc
    18361 ccacttttaa gttattttct tcaataagtt gttttgcatt actcaaagta agtcccacta
    18421 cattaggaac agatgcctga cttgaacctt tacttacgac aacatttata gtatcaccct
    18481 ttttgacatt tgtacttcca ccttcaggtg tctgtgatat tatacaattt tcatcaactt
    18541 cactattata ctcttcactt tttacactca ggtataatcc ttctttttca acagcacttt
    18601 gagcttcttc taatgtcata tttacaagat taggaacagt caaagattta ttgccaaacc
    18661 ctccagcaaa taaaaactta tatgctaaga atacttgagc acacaatatc agtatcaaaa
    18721 cagccgcaat tacttttaat cttcttctag attttgggct ttcctgtttt ttcttctttt
    18781 tcttagttct cttacttgga gtactcttag gtctctgatt ctttttagct ctcattatct
    18841 cttcctcttc ttcatcatca tcttcttcat aaaaatcatc atagtaatct tcatcatcat
    18901 ccaaatcagc tacttcaaca ggcttaacca ctttttcagg agctggtttt gcaagtgttg
    18961 gatttacaac tttattaatt tctttttcat caattttctt agttgcaaaa tcatcatatt
    19021 cttttataaa atctaaatca atattttttt ctatatactc tatatcttct atcaattctt
    19081 cagcagtttg atatctatct gcactagatt tttctgtaag cttttttatt gtagttctta
    19141 cactttgagg aatcctaact ttttcttctg atgtaaagtc tatatcatca ttaatgtgtt
    19201 gaagtgctat agaaattgga ctatctcccc taaatggaac ttttcctatc aacatttcat
    19261 ataaaactat acctagagaa tacaggtcag cattattagt tacaaattta cctttagctt
    19321 gctctggtga aaaataatgc actgaaccta ttatactacc aatattagtc attgttgaat
    19381 ttgaaacagc tttggctata ccaaaatcag ccacttttac tactcttcct tcatttgata
    19441 tgagaatatt atgaggtttt atatctctat gtataattcc ctttttgtgc gctgcactaa
    19501 gtgccatagc tatttgtttt gttatatcta atgcagtata ttcatctaat ataccttcat
    19561 cttgtataat ctcttttaga ttcttcccat ctacaaactc cattacaatg tagtgaactt
    19621 ttccatcttc accaacatca taaacattta ctatatttgg atgtgaaaga cttgctactg
    19681 cttctgcctc tcttttaaac tttgttagaa attcatcatc atctacaaat tcaggtctaa
    19741 gtactttaag tgcaacagtc ctgtttaata atctgtcttt agcctcatat acaaaggcca
    19801 ttcctccatc accaatcttc ctgatgattt catatcgatt tcctaaaatt gtatctccca
    19861 caatatcacc gtcctaatta tacttttatc actataaccg aaacattatc tttaccagaa
    19921 acatcattgg ccatacttat caattcttca cttatattac tagttctctc atattcataa
    19981 tctaatatta aatctcttat atcttcatca tcaataaacc cagttaatcc atctgtcgca
    20041 agaagtatta tatcactttt tttgatttct ttcttaaaaa tatctacaac aaccatatca
    20101 tctgttccaa ttgctctagt tattctattc ctctgtggat gtcttcttgc ctcttcttct
    20161 gtaatgacat gggccatcat aagttcttca accacggaat ggtctatagt tattttatca
    20221 aatttttcat ctgttaacaa ataacatctg ctatctccaa catttgccac atataagaca
    20281 ttattataca ctatagccgt aactaatgta gttcccattc cttcaaattc tatatcttcc
    20341 atagattttt tgtgcacaat tgagtttaca ttattataag cctgttttaa tatatcatct
    20401 atatagtcta tttttacatt atcatgttgt aataagtttt cctttagaaa atcaattata
    20461 ttttctactg ctaatttact ggcgacttca ccttttttat gtccacccat tccatcagct
    20521 atggcaaata ttcctattgg accatgttct gtatctataa cttctccctc acaatagtct
    20581 tcattgtttt ttcttatttt tcctatatgg gaggcacaac tataaaccat acgacttcct
    20641 ccttacaaat tacttgtatt ttcttctcaa ttgcccacaa gctccactaa tatcagaacc
    20701 catagacatc ctaactgtgg caggtatatt gttcttctcc aaactatccc taaatttata
    20761 aataaatgct ttatctggtt tttcgtattc tctttcttca actttattta ttggaattaa
    20821 atttacatga catagcatac cttttaggag cttagctaat gcctttgctt ctttttctga
    20881 gtcatttacc ccttttataa gagaatattc aaatgtaacc cttctatttg tcttttttat
    20941 ataatatcta catgcattca atatttcttc aatagaataa gcatttgcta caggcataat
    21001 ttttcttcgt tcttcatcat atggtgaatg aagtgataaa gctaaattta tagctatttc
    21061 taagtctgcc aactcataca ttttaggtac tattccacaa gttgaaagag ttatatgtct
    21121 ataccctata ttaagaccat ttttttcgtt aattattttt aaaaattgtt ttgtattttc
    21181 aaagttatca agtggctcac cactccccat caatacaaga tttgataccc tcttaccagt
    21241 atcttcttga attttaataa cttggtctaa aatttcccat ggctctaagt ttctaattaa
    21301 tccatccatt gtagatgcac aaaaattaca tcccatccta caacctactt ggttagaaac
    21361 acagacagta actctactat cataatccat catcacagtt tctattatat ttccatcatc
    21421 taataaaaac aaatattttt ttgtattatc taccttagat tctaacttta attctatatc
    21481 tatatgccct atacatgaaa cctcttctaa tttatttctc aaactttttg gtatattgtt
    21541 catatcatca aaagtttttg cacccttata tatccaagag aatatttgac ttcctctaaa
    21601 gggcttttca tctatagttt tcataaattc tttaagttca tcttcagtaa aattttttaa
    21661 tactatcttt ttcttttcca ttctctcact accttattct ctttaatttt gctatgaaaa
    21721 aaccatctat accatgaata ttaggatata tctttaaata tcctttatct tgattgtcta
    21781 agtctacatt tactgtatca attggaacaa attcaaagtt gtgattttct tcaacaaaag
    21841 aagtaactat atttatattc tccacatctt gaattgtaca tgtactatat actaaagttc
    21901 caccaacttt gacatattta gatgcatttt ctaaaatttt cttttgtata gaagtgatgt
    21961 cttttaactc ttcttctttc ttatacttaa tttctggttt acgtcttatt ataccaaaac
    22021 cagagcaagg aacatctgct aaaacataat caaatttact tatactattt tcatcaatct
    22081 cagaagcatc aaatctttct acaaacacat ttttaagccc caatctattt acagtagagt
    22141 ttataagctt tagtttatgc tcaaaaatat ctctagctac tacttgacca gtattgttca
    22201 ttaaagtagc taagtgagta gatttccctc caggagcact acatacatcc aaaacaaatg
    22261 aaccttcttt tggattaatt actttcccta ctatcataga acttatatct tgaattgtaa
    22321 ataaaccagc cttaaataat tcattttttt ctatattttt cattttttcg actttaatag
    22381 cttcttctac cataggaact tttaaacata caatacccat ttcacttaat ttttcaataa
    22441 gttcttctct acttatttta agtgtattcg ttcttatata gatactaggc ttttcattat
    22501 ttgcttccaa caaatcttca gcaaattctt gtccaaattt atctatccag ttttttataa
    22561 tccaagagtt ataggaatac tttatagata agtattttac actatcttcc tcagttatgt
    22621 ccattatagt ctctttagct cttatttcat ttctaagaat agcatttatg aaaccagaag
    22681 attttttatc atatttctta gataatttta cagtttcatt aactgctgca taatctgata
    22741 tactatctaa aaataaaatc tgatatgttc ccattcttaa aaagatttta acataagttg
    22801 acattttttt tacctttatt tttgaaagtt tattgattat ataatctaaa taatatttat
    22861 tttctattac tccataaatt aactctgttg caagtcctct atccatatca cttatttcta
    22921 aatttttaaa atgcttattt attgcaatat ttgaataatt gtcatttttt tctatatcac
    22981 ataatacttt aaatccaact tctcttgcat ccatataaat ttctcccttt tattaaacat
    23041 aaaaaagggt tgtttctaaa caacccactt tacttttagt catttcttct ttgagctatt
    23101 agtaacaatc taagtaattg aagtattgaa accaatgctg ctgcaacata tgttaaagct
    23161 gctgctgaaa gtactcttct actttgtctt gactcacttt catctataat ccctaaattc
    23221 ccaagttgaa cgattgctct acttgaagca ttaaattcta caggcaatgt tattatttgg
    23281 aataacactg aagccgaaaa caatagtata ccaattttta aaaatggacc agccataata
    23341 aatcctaaaa atattaaaaa ccaagatata cttgaagcaa aattcactac tggtactaaa
    23401 ctacttctta tttgaagagg tgcataacct ttagcatgtt gtatggcatg accacactca
    23461 tgtgcagcta ctgcaacaga agttatagat gttccataat atacatcttc tgacaacctt
    23521 acagcctttc ttcttgggtc ataatggtca cttagatgcc ctctaaccat ttctatcttt
    23581 acatcataca aaccatttga atcaagtact cttcttgctg tttgctctcc agtatatcct
    23641 cgacgtgtat ttactcttaa atacttattt gttgttgaac tcactttaaa ttgtgcatat
    23701 atagtaagta atatagctgg aattaataca accattgttg ggtcaaatcc ccaaaaaccg
    23761 ccatatacag ggtacataaa taacactctc ctaaaatata tttttattat acatcctctt
    23821 aatattcact taacttaaaa acagtttaat tacaaactaa tatatttttt cctgttaaaa
    23881 agcctatagc tttttcaata tccatcatgt ctacattagt atttacacaa ggtccattag
    23941 gtcttttgtt aaatacacct aaaacaggaa tttttttaat atcttgtatt ccagatgtca
    24001 aatctctttc acatgcaaca gctacaacag ctttaggttt agtgtccatt ataatttttc
    24061 tagctagggt tcctcctgta gctacaaata tttttacatt agttttttcc tttagcttaa
    24121 ttaattctcc tatgttgcat cttccacatt ctttacaatt atctatatca ttagtaactt
    24181 ttaatttaca actattctct tgaatacaat gaggtattaa aattattata tcctctggat
    24241 taaaattata tttattactg tatatatatt cattatttaa ctttatatat attcttctaa
    24301 tatcactttt tgacatacca aatgatgatg caatgaaaga tataatagga aataatccac
    24361 tgacaatatt aaaatttatt ttcattatat ttgagttaac atactttcct ttaattactc
    24421 tataagtaac tgctgttgaa catagtatta taagtattag tgatattatt ataatattta
    24481 tcatcaagga gaatatttga gttaaactta ttataaaaaa attaacaact cctatcaaaa
    24541 ttcctaatat taaaatcaaa atcccaacac ttgttaaata cttctttata tctgtcatac
    24601 ttttcaccta acccaatact aaaccagttt ctatagtatt cccttttata tattcaccaa
    24661 ccaacattct ctttttattc ggcatctgaa tttcttcaat taaaagtaca ttatctatag
    24721 tacttacttt tatcccatct ttgcttacat caattattgt acctacatct tttgtgcttt
    24781 tttcatctaa cactttagtt ttccaaactt tcattatgac atcattatag gtagtataag
    24841 cacttggcca tggatttact cctctaacta aattgtgtat ttctctggca ctttttgaaa
    24901 aatctatgtt acctaatgat ttattcatta ttggcgcata ggaaaattct tcatgatttt
    24961 gtacttctct tggagcattt ccttcttcaa ttaatcttaa tgtttctttt aaagtttctg
    25021 cgcctatatt catcatttta tcatgaagtt ctcctgctgt tatattttca tcaagattta
    25081 cttctgtctt tagtatcata tctccagtat ctaatccttc atccatatac atagttgtaa
    25141 caccagtctt ttcttcacca tttattatta cccaatttat aggtgccgca cctctatatt
    25201 ttggaagtaa agaaacatga acatttatac atccaagttt aggaatctct aatatttctt
    25261 ttggaagtat ctgtccaaaa gctacaacta ctattacatc tggatttaaa gatttaattt
    25321 tatctataaa ttctttatct ctagccttta ctggttgata tacaggtata ttattttcaa
    25381 ttgccagttc ttttactgga ctcataccta gttttttacc tcttcctttt ggtttatctg
    25441 gttgagttac aacacccaat atttcatact tctcatctat tattttttgt aaacatggaa
    25501 ctgctatatc aggagttccc ataaatacta ttttcatcaa atcaactcct actacttttc
    25561 tattttgtca acaaataaaa ttccatctaa gtggtctatc tcatgacaaa atgctctagc
    25621 taaaagttct tctccctcta actctattgt ttcaccattt ctatttaaag ctctgacctt
    25681 tacataattt ggtcttctaa catttcccgc ttctccaaca acacttaaac atccttcctc
    25741 atctatttgc tccccagatg tttctattat ttcaggattt ataagttcta taagctcttc
    25801 tccaatatct attactacta ctctttttaa tattccaact tgaggtgcag ccagtccaac
    25861 accatctgca tcatacatag tttctgccat atcatctaat aattgtatta tcttttcatc
    25921 aattttttca accttttttg atttttttct taatactggt tctcctattt gaactatttg
    25981 tcttaaagcc attataattc ctcctaaatt tataatacac tgtttggatt aatatctata
    26041 gatacattga tattcttatc aaatatcaaa tctcgttttg ttatacatat atattttatt
    26101 atacccttta agagattaat ttcaatattt tcatctttaa agagtatttg ccatctataa
    26161 ttttgattta tttttgatat tgaacatgga tttggaccta atataaatcc taaatcattt
    26221 ataccccttt tttctaataa ataaatcaat gatgcatgca tattttttat attttttatc
    26281 actaatcttt catcttcacc actaacaact acacttaaca tattattaaa aggagaatat
    26341 ccaaatgctt ttcttatttt tatctcatct tcataaaaac cctcataatc atattcaata
    26401 gcatgcttaa tagcatagtg ttcagtgtca taagtctgaa gtactacttt tccctcttta
    26461 tcagctctcc ctgctcttcc agagacttga gttatcaatt gaaatgtagt ttcaaaactt
    26521 ttaaagtctg gaaaatttaa tatcatgtct gcagacaaaa tacctactaa agttacattc
    26581 tcaaaatcca gccctttact taacatctgt gttccaatca gtacatctgc ttctttatct
    26641 ttaaatttat ttaatatctc atctaaagca cctttttttg aagttgtatc tttatccatt
    26701 ctcaaagttt ttatatctgg aaaaatatat tttaattcct cttcaatttt ttgagttcca
    26761 actccaaatg gcttaacata agtactttta cattcaggac actcttttgg aatttctttc
    26821 tcatatccac aatagtggca tcttccagta ttacttttct tatgataagt taaagatata
    26881 tcacaatttt cacattgaaa cacatatcca cactttctac aagatacaaa atttgcataa
    26941 cctcttctgt ttaaaaatag tattacttga ttattttctt caatcgcata acgtatttct
    27001 ttttgtaatt tcaaactaaa tatacttcta tttcctttat ctaactcatc tttcatgtct
    27061 accacttcaa tgtttggaag aggcttatca tttgctctac tttttatatt tataagtttg
    27121 tattctccag attttgccct ataatactct tcaattgagg gcgttgctga acctaaaata
    27181 agagttatat tattttttaa tgccataaat ctagcaactt ctatagcatt aaattttgga
    27241 ttcttctcag acttatatga tgactcatga cattcatcaa ttattattaa gcctaaggaa
    27301 ttaaaaggtg caaataaagc tgacctagct ccaattaaca ctcttacttt acctgctttg
    27361 acagctttgt aaacatcatg tttttctcct tcagatagtt tactgtggaa cactccaact
    27421 aaatctccaa acctaccctt tagcctatct attgtttgag gagttaatgc tatctcaggt
    27481 actaagaata tactgtctaa gccttgattt agagcaaatt ctattatttc catgtaaact
    27541 tcagtttttc cacttccagt tactccatga attaagtatg gttttttatc atctacaaac
    27601 atattcgact ttatctcatc aactgcttct tgttgctcat tgtttaattt tatacttttt
    27661 agtacggatt tgtaaatact ttttggctct ctataataat ccttaaattc tagggttatt
    27721 agctttttct tacttagaga atttatactt tgttttgaag catttaataa atccaataaa
    27781 tcatttatct ctacattttc attattttta agaaaactta atatctcttt ttgtttactt
    27841 cccacattta ttttattttg ctctatataa tcgtcaatct tatcactttc taaactcaaa
    27901 gatatataac atactttctt ttcatttttg tgatttttat attcccaaca taattttata
    27961 attccatttt tattcattgt gtacaaagaa ctatttaagt ttggtatata ttttaactta
    28021 tcaaccttaa ttttaccttt actatcaatc actttctcta ctatttctct atttttatca
    28081 cttaaagttg atattttttc cttcaattca atattattta atccacttaa actttcacct
    28141 aataggacta ctttataatt atttaatttg tatccctttg gatatatcaa atttatacat
    28201 tctatataag tacacaaata tctatttttc atccaataaa ccaactctaa atcttctttt
    28261 ctaaatattg gattttcatc taatatatca ataatttctt ttatttttat tttttcatct
    28321 aagctatctg taaattgaaa tacaaaggct tctgttggtt tattaccttt tccaaatggt
    28381 actaatattc tgtgcccaat ttttattaca tcagataaaa atacaggaat ttgatatgta
    28441 aataaattat ctgtatatat agtattactt ctaactatta cctttgcata ttttttcatt
    28501 ataaaacctc tacttaaatt taatatattg ttcatatttt aatatacttt acaagatatt
    28561 aaaatctcaa aatttataag caatttcaag ttattaatat taactttatt ttaataatta
    28621 actattaatt atattttata ctttatgaca aaataaatgc tgaaaactac aatttaactg
    28681 acatttgcga gtttttactc gctaaaatta aattgcagct ttcagccact ttagctgtga
    28741 taaaatacac aaatatcata tttaaaaaag gtcttatttc tcaagcaacg ctttaacttt
    28801 atctaaaata acattggcta cttcttcttt tttcatctta ggatactcag taatatttcc
    28861 ctctacatct attattttta caatattagt atcagctcta aaaccagcac cttctttagt
    28921 taaatcattt gccacaataa aatctaaatt tttctttttt atttttcctt tggcatgttc
    28981 tataaggtca ttagtttcag ctgcaaatcc aattagtatc ttatcttctt ttatttttcc
    29041 tatttcataa gcaatatcat aatttctact tagttctatt gataaatcat cattcttctt
    29101 tttaattttt ttgtcagaat aagtttttgg tttataatct gcaactgctg cactttgaat
    29161 tactatttta ttttcactta aatttgatac tactgcttca tacaaatctt gtgctgactc
    29221 tatttgaaca aattttttaa gattttgtgg aatagaaaga tttgtaggac ctgatattaa
    29281 tgttacatca gcacctctag ctatagcttc tcttgctata gaatatccca ttttaccaga
    29341 agacctatta gttaaatatc ttactgggtc tatgctctct acagttggac cagctgtaac
    29401 tatcatactt tgacctttta aatcttgctc tttagtaaga ttagtcaaaa cttcctctac
    29461 tattatatct ggattagcta gtttacctgt tccaatatct ccacatgcaa gccttccact
    29521 ttccggttca ataaatttat atccaaagct ctttaaagtt tgtatatttt tttgaacaat
    29581 tggattttca tacatattag tattcatagc tggtgctata agaacctgtg cttttgttgc
    29641 cataacagta gttgtcaaca tatcgtcagc tataccattt gcaatcttgc ctataacatt
    29701 tgcacttgct ggcactatta agaataaatc tgcttttttt gctaatgata tatgttcaac
    29761 ttcccaagtt tttggttctt caaacatatc ttctactaca taattttgac tcagcgattg
    29821 aaatgtaagt ggtttaacaa attctgttgc tgattttgtc attataacat ggatatttgc
    29881 atttagtttt tttaacttac ttacaacatc acaagcctta tatgcagcta taccgccact
    29941 tatgccaatt acaacagttt tatcttttag catgacctta ctcctcttct gaaatttgtt
    30001 ggtgttgctc agcatgatgt ctagcttctt ctatctctat ttcctcttct gtcaataatc
    30061 tatatgttat ttttccactt gcaacttctt tagttgctac acatacaggc ttttccttag
    30121 ttttatttga aacatatggt tcttctccat caattaattt tcttgctctc tttgaaacag
    30181 tccctactaa atagtatctg ttgtctattt tttctagtac ctcattgata gatggtttta
    30241 acataattat aattcctcct taaatttctc tattataata tttttatatc tgctaacttt
    30301 attcttttca gatgatatta taccttctat ttctttagca gatgttttta catcttcatt
    30361 aaatataaaa taatcataat ccttaatcat tttaatttct tcatatgcac agctaaatct
    30421 cttctctatt tcagcttctg tttctgtacc tcttccaaca attctatttt ttaattcttc
    30481 aagtgatggt ggtagtacaa atataaatac tccctctggg caaacttctt ttatttgttt
    30541 tgctccttgc atttcaatct ccagtaatac atcttgtcct ttttctaaac attccattat
    30601 tgccgctttt ggagttccat aaaaattatc ataaatttga gcatactcca aaaactcacc
    30661 tttttctatc atctcttcaa acttttcctt acttatgaag aaataattta ctccatcaac
    30721 ttctccagtt ctgggttttc ttgtagtagc tgatacagaa agttttattg tatcattttc
    30781 tttaagtagt tctttgcaaa tagtaccttt tcctgcacct gatggtcctg atacaactag
    30841 caataatcct tttttcacaa acatttaagc attccccttc taatattgta ttcttactct
    30901 atattttgta tttgttctct tattttttcc aattcgcttt ttacttctac tactaaatta
    30961 gttatattta tatcagatga cttcgaacct atagtgttag tttctctatt catctcttgt
    31021 attaagaaat ctatttttct acctatagag tcgtctttaa atatagtatt tttaagttgc
    31081 cctatatgac ttttaaatct aactatttct tctgttatac tgcttttatc tgcatatatt
    31141 gcaacttctt gtgctaatct attctcatct attatacttg ggtcatccag taattcactt
    31201 attctcaaat tcaatttttc tctataatct tctacaacac tacttgaata tttttcaatc
    31261 tcttctatat gattttttaa taaatcacat ctcatggcaa tatcttcagc taatttttta
    31321 ccttcttcac ttctcatttc tcttaatttg attaatgcat cttcaactgc ttgattcaac
    31381 attgaccaca ataaatcttc atcttcttcc ttttcttcta ttttcacaat atcaggaaac
    31441 tttgcaacat tcataacgct aatatcatct ataatatcaa atttattttt tatttctttt
    31501 agtatgtcta tatactgaga tgctaatccc tcatcaaaat ttaagtttac atcttctttg
    31561 cctaataagt caaactttat gtataaatct actcttcctc tttttacata attttttact
    31621 aaatttctaa ctttatcctc taaaaatgaa atttttcttg gaagacgtat gtttatatct
    31681 gaatacttat gatttatcgt tttacactct actaaaaagt aataattatc atccttgtat
    31741 tctcctcttc caaaaccagt catacttata gccattaatt aaacctccaa aataccttca
    31801 catattttta ctgctggacc tgtcatataa gagaaatctc ctacatctat tttaactgtt
    31861 ccaccttgag acgttacatt tacactactt tctaccatat taagtaaatt gcacactatt
    31921 gctgatgcag tcataccagt accacaacct aaagtatatc cacaacctct ttcccaagta
    31981 taaacatgta tattatactt atcttctacc tttacaaaat ttacattcgt tttttcagga
    32041 aatattttat tattttcaat ctcttttcca tatttacaaa catcatctac atctaattca
    32101 tctactataa ctactgtatg aggaaccccc atcaacatag aagtaacttt aagctcccta
    32161 tctaaaacct ttatactttc ttgcacaaaa cgttctttat ttgtaagtac aggaacgtct
    32221 ttagctataa aacttccttt tcccatattg actcttatag agtttatttc tctattggta
    32281 agatttattt ttatatcttt tataccatct aatgtatcta ctgtaaaact ttctttttta
    32341 actatacaat tatcataaac aaatttacaa aaacatctaa ggccatttcc acacatagct
    32401 gctcttgaac catcagaatt ataatatacc atttctacat ctgcaacttt tgaatctttc
    32461 acaactaaca atccatccgc tcctacagaa aatcttctat ggcatacttt ttttgctaaa
    32521 gcagtataat cagatggatt tatctggtcg aatcttccat ctattgctat aaaatcattt
    32581 cctattccat gtagtttcca aaatttcata agtatcgctc cttcgtaaat taacgcttaa
    32641 actattataa cataaaaaaa ttcccataaa cttataattt atgggaaaag ttttgtaatg
    32701 acaactataa tttgaggatg tgagggagag ttgccattac aattagggta attatattat
    32761 gtttttaagc tagttctttc tatgtttata tattaatatt tctatatgaa ttttatgtat
    32821 gttttattta aactgtctat gaatttttta attaaacatc tggtaactag ctataatcct
    32881 tctagtagat atctattaag atacacctat taattcttta agtgttttta aaacatagtc
    32941 taaatcttcc ttagtaatat ctacatgagt tacaaatcta tattcaccat tttccatttt
    33001 attaattttt atatttcttt caaaaaattc ttttattaaa acatcctctt ttataatatc
    33061 ttcactcatc ttaaaaaata ccatacttat atctggatta acattattta cttcaatgcc
    33121 atcaatttta tttaattcac aagctaaata ttttgcattt tcatggtctt cattcaatct
    33181 taaagtcatt ttttcaatgg caattatacc agctgctgca actataccta cttgtctcat
    33241 tcccccaccc ataacttttt gctttcttct agcttttgct ataaattctt tacttccagc
    33301 aagtatagaa cccattggtg cagctaaacc ttttgacaca cagaacataa cactatcaca
    33361 acactttgct atttctttag cttctacacc caaagttaat gctgcgttaa ataatcttgc
    33421 tccatctaaa tgtactggta agttatgttt ctcagctatt tttttaattt ctcttaaatt
    33481 atcaagactc acaactgttc cacctgaata tgcattttct acacatataa gccctgtctg
    33541 tggttcatgt atgtcatctc ttctaattgc cttttcaaca agttcaggat ttagagctcc
    33601 actttcgtct tcatctatag ttctaagctg aactccagct attacagcag gtgccccaac
    33661 ctcatgagtc acaatgtgat aacctttacc aataattatt tcttgccctc ttaggcaatg
    33721 agtaaataga gctaattgat tcccaaaagt tccacttgga aggaaaatag catcttcttt
    33781 tccaacttta gctgctgcta attcttcaag tttatttaca gtagggtcat ctctaaagat
    33841 tgaatctcca acaggagcct ttgccatagc ttctctcatt tcgtcagtag gcatagtaac
    33901 agtatcactt cttaaatcga taaatctcat tttttcaacc ttctttcata tttatatact
    33961 atagaacctt aaaattgatt ttttctgtaa agttcatata ctttcatagc ttatactcta
    34021 cacaataatt atactatatt tactttatat ttaatctact ttaaattatt aattttaaaa
    34081 ataaagtttc ctctctaata aatataaata attatacaat ttaaatatta atctctattg
    34141 tttaaattcc ccctagtcac aaagcgtata ttatgtgtat aattaattta ctgactcatt
    34201 ttggtcaaag aaaggggtgc tataaatggc attagatgga ttagttatac attcaatagt
    34261 cgatgaatta tcatcaaaac ttacaggtgg aaaaatagat aagatacatc aacctgaaga
    34321 tgatgaggta atttttaata taagaaataa taaagaaaat tttagattgg ttttaagtgc
    34381 aagtgcctca aatcctagag tttatcttac aagtaattat caaaaagaaa accctctaaa
    34441 agcgcctatg ttttgtatgt tacttagaaa atacatacaa ggtggaaata tagtagaaat
    34501 ttctcaaata ggttttgaaa gaataataaa aataagtgtt gaatctttag atgaattaaa
    34561 agaaaagaca gttaaaaata ttatgattga aattatggga agacatagca acataataat
    34621 aactcatggt gaagaaaata aaattataga ttctataaaa agagtccctt ttagcataag
    34681 tagagttcgt caagttttac ctggtcatga ttattcattg ccaccagaac aaaacaaact
    34741 caaccctctt gatgatatat ctaaggattt gtttattaaa aacctagagg aattggaagg
    34801 acctatcttt aagtctatat attctaaatt tctaggtata agccctatta tagctaaaga
    34861 aatttgctac agagcaggtg taaatcaaaa tgctatcata aaggatatat ctgatgaaca
    34921 atttgatgct ttacacaaag tattttgtaa tttattcaat gatataaatt ctaacaaata
    34981 ctctccttgc attattatag ataaaaaggt ggatagggta gttgatttca gttgtataaa
    35041 ccttacatta tttagcgatt tatcatatat aaataaggat agtatgtctc gtattctgga
    35101 agatttctat agaactaagg atattaaaga tagaattaat caacgttcat ctgatttaaa
    35161 gaagagtata tctgttaagc ttgatagact ttataataaa cttaaaaaac aagaagaaga
    35221 attatcagaa tccgaaaatg cagatattta taagataaaa ggagaattga ttacttcata
    35281 tatttatatg gtagaaaaag gtatggaaag tattgaagtt gctaacttct atgatgaaaa
    35341 ttgtaatgat gtaacaatag aattaaataa aaacttgaca ccatctgaaa atgctcaaaa
    35401 atactttaaa aagtataaca aaatgaaaca tgctaaagtc gagatatctc atcaaatttc
    35461 cttaaataag gaagaaatag attacttaga aaacataatt ttaagtattg aaaactgtga
    35521 aaatttagct gaattacaag atataaaaga agaacttgct aaagttggat acatcaagac
    35581 tcaaaagaaa aacagtaaaa aggatactat cccatctaca aaacctcatg aatttgtttc
    35641 ttctgatgga tttaaaatat tggttggtaa aaacaataag caaaatgact atcttacact
    35701 aagacttgct gataatgatg acttatggat gcatacaaag aatattcctg gttctcatgt
    35761 aataataaag tgtgctggta aggaagtccc tgataatact gtatttgaag gagctatgct
    35821 agcagcattc tttagtaagt caaaactttc ttctcaggtg cctgtagact atactaagag
    35881 aaaaaatgtg aaaaaaccta gtggttctaa accaggtatg gttatttatg aaactaacag
    35941 tactatttat gttactcctg aagaagaaac agtagccaag cttaaggtta aatctgaata
    36001 aattctgcac taaatacaaa ataaatgtta gacaactaca cattatcatt ctaaataaaa
    36061 atagtggcct tcttataaag tacaataata aggccacttt ctaattagct tacttttaat
    36121 tttctaacaa aatacttttc tgttttaata actatactta tattcccaac aaatattttc
    36181 agtcttctta tatagatgta attaaaaagt taacactaaa agctattttt taatttattg
    36241 atttgtttta gtaattcatt atattctgat tcatacaatt ctttttttag attatctttt
    36301 tctatagata acatagatat aacagttgta agtctatttt ctaatactag aagattttct
    36361 tttttgattt ggttttctct actaggagtt tttttatttc tgctaattgt atattcgtca
    36421 taattacaat caaactccct tattttagca tcttttatct ctataatata gttacaaata
    36481 tgtgatacaa atactctatc atgagacact ataagcatag ttttatcagt atttatcagt
    36541 gccttttcca gtgcttccat agattttata tctaagtaat ttgttggttc atcaaatact
    36601 aaaaaattat tatcttccaa tattatttta catagtgcta tttttacctt ttctccacca
    36661 ctaagtactt ttactttttt gtagacatca tcacctttaa acccaaatag gcttaagttt
    36721 atccttataa aagattcatc aaatgaacta ttaactttag tattgtatag aacactcttt
    36781 tcctcatcta ataaactttg attttggtca aaataaccta cttttacctt gttatttatt
    36841 tttatattgt catttttatc agccaatatt tcttttatca gagtactttt tccacaccca
    36901 ttatcaccta ataatgctat ctttttacct ctttttatct taaaggaaac attatctaac
    36961 aggagcttat tttctaactt tagagtcata tcttttacct ctactagatt tttgctaatt
    37021 atctccatac catcttgaat cttaatgttc atttctttag aaactttagg tttattcttt
    37081 acctcaagtt tatcaattct gctttttata gccttcacat ttgagtccaa ctttttctta
    37141 ttagtctgac cacccatttt gtgcaaccta gcttctgaat tacccattct ttttggtgtt
    37201 tttcttatgc catcacttaa agctttttta tataaaagag ctttttcaag cctttttttc
    37261 tctttaacat attcttgata ctcaaaatca gctcttttta cttcttcatc tttttgcatt
    37321 aaataatcag tgtaattgcc tttgtaagct tttagttttc catcttctag ttctaatata
    37381 gttgtacata actcatccag aaaacgtcta tcatgagata ttaataataa tgctccctca
    37441 tgccttttaa acatatcttc caaaacccca atgctttttt tatctaagtt tgaagttggc
    37501 tcatcagcta ttatgatatt tttcttatta ctcagcgcat ctgctatttt taacttaacc
    37561 ttttcccctc ctgataagtg ttcttcaaat ttatctggag catttaaaag actcttctcc
    37621 ttactatgac cacatgtttc aatattattt tcactctgac ttatataaga atagctttct
    37681 gtaaggtaag tatatccttc atcaatttct atttctccca atattgcttt taataatgtt
    37741 gtttttcctt gaccatttga accaactaga cctattttgt cattttctaa tatttcaagt
    37801 ttatctatat ccaaaattaa tttatctgca taatatttct ttaaattttc tacttttact
    37861 aacaacataa aaaatccctc cttaacacac ttaaatataa ggagagattc tataaatagg
    37921 cataacaaat aaacgtatag actataatct actctcctta atttaagcat tgcaaataaa
    37981 gccaccaaaa taggcttttc aaaaattaca atactttaaa ttataaaaaa tagattatat
    38041 tctcattgtc ctagttacct tgccctttct ttcatttatt tttaatcatt atatcaacat
    38101 taattacaaa tgtctataga aaattaacta attttagtta ttcaatatac aacttattct
    38161 ttaaatttat tcttcttcaa ctttaaagtc ctgattattt aaaattctgt ttaatacaat
    38221 tccaacaatt gcagctaaac taagaccagt tatctttact gtacttgtta tagggattcc
    38281 aacagaaata cctttattag ataaatatgt tgttccaaga cctattaata atataactgc
    38341 tatgattaat atatttattt tactttctac acaagaactg tcccttatag tttttaatcc
    38401 tacataagtt atcatcgaaa atagcattat actaattcca cccataactg aacctggtat
    38461 actttgaaga aatccaccaa acttgcctac acatgcaagc aatatagcaa atattgctgt
    38521 acgtctaagt attgaagggt catagttttt agttatagca agtactgctg tattttctcc
    38581 ataagttgta tttgctggtc ctcctaaaca ccctgcaact atagtcgcaa atccatcccc
    38641 aagtaatgtt ctatttaatc cgggattttc tataaagttt ttacctacta cagcaccatt
    38701 agtagtcata tctcctatat gttccataaa tacagctaat acaactggag atataatcac
    38761 aattgctcct aaactgaact taggaactgt aaagttaggt attgcaaata aacttgcttc
    38821 tgtaatagta gttatatcta ctaatcttaa tatcaaacag attatatacc cagaaaaaac
    38881 tgctattaat attcctaatt gttttataaa tcctctacca aacttattgg ttaaaattgc
    38941 tattgctaaa gttataaatg ctattacaaa attggctgaa gccatactaa aagctgttgg
    39001 caataaattt aatcctataa ctactatcat agctcctgta acttgtgcag gaaaatataa
    39061 tttaatttta tttacaccaa ctacttttac tataatcgac attataatat aaattaatcc
    39121 tgctactatt ataccacctt gagcatatgc taaatctcca ccatatgcct ctttagctgc
    39181 tagtataact ggtataaacg caaaacttga acctaaaaag gcaggtactt ttccttctgt
    39241 acaaaaatga aatatcaatg taccaacacc agcacagaaa attgcaactg acggattaaa
    39301 acctgtcaaa atgggaacta atactgtcgc tccaaacatg gctaatagat gttgtaaaga
    39361 cattatcgtt tttttcataa aaacctccaa aattattata tataaataaa tcctctgttt
    39421 aattaatatc ttttaattaa ttatcattcc ctagattcta ttttttaacc tctatatact
    39481 tattatataa tttatcatta ttttacattt tacgacatca aaaactcaaa taaaggagaa
    39541 taaaaactac attaagactc acatccataa aattataata tttattttgt gcaatctatg
    39601 taagctttat cctcctccct gactattcaa tgctaagctt ttatataata cttaaaaata
    39661 attattcttt gattgtaact gaatcttctc catcaatttc taataaactg acagatataa
    39721 tttcatgtct agaagtaggt acattttttc ctacataatc tgctcttata ggcaactctc
    39781 tatgccctct gtccactagc actgctaatt gtattgattt aggtcttcct atatctataa
    39841 tagcatctag tgaagctctc acagttcttc cagtgtataa aacatcatca actaaaacta
    39901 ctgtcttatc atttacatta aaatctaaat aagttccttt aactacaggt tcaacatgaa
    39961 ttttttccaa atcatctcta tacaaagtta tatcaatatc tcctgtatct acttttgttc
    40021 cttctatttg ttctattttc ttagaaattc tatttgcaat tggcacacct ctagtcttta
    40081 ttccaactaa aactagattt tctacacctt tatttctttc aattatttca tgacttattc
    40141 tagtaattgc tcttgctatt gccttttcat ccattaattg agctttttct accatatcat
    40201 aattattgtc aaagatataa tatatctatt tgacaaatct actcctttct tttaattttt
    40261 tataaattta tttttattta aaatttcaat ttaaacaaca aaaaaacttc tcatcacaag
    40321 acaagaagct cttatataaa aaatatacag tgcaatttag caattgtctt acgatatctc
    40381 tgtatcgttt aaagataatt ttttaatcta tcaaatcaaa ttatatattt atatttcaaa
    40441 tttttcaagc ttttttaaac aaaatacttt aatataagat attttattta aatttcacta
    40501 aatttattta cttatataaa aacaaaaaat gatttataag tattatacaa atggttattt
    40561 tatcttttta ataacttcct taaaatactc aggtaattct gaattaaatt cgatatattc
    40621 cttagtagta ggatgtataa atcccaactt cttagcgtgc aaagtttgtc cttttaattt
    40681 aaatttagtt tcttttggac catatacata atcacctaaa agtgggtgat ttatagacaa
    40741 agcatgaact cttatttgat gagttctacc agtttcaagc ctagctctca tatgtgtaaa
    40801 cttatcaaat ctttctacaa cttcaaagtg agtgattgca ttttttccat cttttactac
    40861 agccattttt aatctatcct taggatttct ccctataggt ttatcaacag ttattttatc
    40921 ttctttaacc acaccatagc atataaattc atactcccta gttatagtat gttcctttaa
    40981 ctgttctgct agaaaattat gtgcataatt gttcttagct atcataagaa gaccagaagt
    41041 atctttgtct attctatgaa ctataccagg tctaataact ccatttattg atgacaactt
    41101 atctttacaa tgatataaaa tcccgtttac taacgtattt tcatagtttc caggagcagg
    41161 atggacaacc atatcctgag gtttatttat tattaagaca tcatcatctt catatacaat
    41221 atctattgga atatcttgag gtaaaacttc taatacttta ggttctggta tctctataac
    41281 aatattatct tcctctttaa ccagatatct agctttttct actttattat taacctttac
    41341 ttttccatct tttataattt tttgtatata acttcttgac atatcaccta attgttctgc
    41401 tagataaata tcaagtctaa cttcttcttc ctcttcaagt actaaaaact cttttacttc
    41461 atccattata tcacctactt ttactttcaa aaaataaaac atatatacat aaaaacacag
    41521 ttcctacaac tacaaataca tcagctatat tgaatacata ttcccatata attctaaagt
    41581 cgaagtaatc tactacaaaa cctaatcgta ctctatcaat tagatttccc aatgcaccag
    41641 atataattaa tataattccc aaccttccaa atatatgtac tttccttgta ttaagatagt
    41701 atagtccaaa tactgttgca agtaatgcaa caattataaa tatccattga ttattttgta
    41761 ataatccaaa tgctgcacct ctattttcga cataagttaa atgaaataca ttatttatta
    41821 ttggtattgt tgatacatcc accaaattat tcaataccca tattttagac agttggtcta
    41881 aacctatgag tagaattatt attaatatat atagcaatga tttttccccc tataaattat
    41941 ttaaaaacca attttatttg aagcacacta ttattattat acaaaaaaaa tgctctaaag
    42001 agcaacttta ttaaaattgt attttcttag taaagctaga acaaaattta aaatagtact
    42061 ccttttttta tattgtagat ttctacatat ttaaaatcat atcattatgt ataaaaaatt
    42121 ttaaaatacc atactaatca atattttttg tgtattttat agattaaaga ttaatgatgt
    42181 ctgtaattta aacttacaat caccactaat cttcaaacaa atatttttac ttttgcactt
    42241 gcttattttt atctaaatgt tgtataagtt cagatactgt tacgaattta tatcctctct
    42301 cttttaattt aggaattact acttctaaag cttgtatagt ttgtgattta tcatttcttt
    42361 tagtgttata atcatgtaaa agtattatat taccattttg aacctttgta aggatagtat
    42421 ttataattgc atctactcca gggttagacc aatctctagg gtctaagttt gaccaaagaa
    42481 ttatattcat gcctttagaa actataatat cacagacact tttactcatg gctctatatg
    42541 gaggtctaaa tatctttggt tctactccta ttacactttt tataatattt tgcgtatctg
    42601 ttatttcttt ttcaacacta ctataactat tttttgcaac atttatatgt gtaaatgtat
    42661 gattccctat ttcatgcccc tcatcatatt gtctttttaa taattctttg ttatattcta
    42721 ctttttctcc aactacaaaa aaagttgctt ttacatcatt tttctttaat atatcaagta
    42781 cttgtggtgt aaaatcctca tctggaccat catcaaaagt caatgctaaa attttttcat
    42841 cctcatttcc tttttttatt attacatctt cataatcgtc ttttatattg tcatttaaac
    42901 tatatgcttc ttttgaacta tcttgattat gtgtattatg actatatgta tatacaccta
    42961 ctacagataa taaacatata catatacccc atattatttt cttcatgtca ttacctcttt
    43021 tctaattcat tctagcaata tattttataa tgtcagtttt ttaatctctc aatattccat
    43081 ttttatttaa atcagttaaa tttgttaggt cttctgaata aaagttagaa tcttctacat
    43141 cagggttttg cattgcatca cctaataaat tattttcttt ctttgcacaa tcattacata
    43201 aacttgtatc tggcaatata tccaatcttt ctaaatctat ttgattatga cataaatcac
    43261 aaatcccata tgttccattc tctattttag ataatgctaa gtctatttga tacaatcttc
    43321 cctcttcatg atttattaga ctgttttgca tattttgcat atataaatct gttcccatat
    43381 ctcctatatg attatcataa ctagataatt ctcctgatga atacttttca cttgtatgtt
    43441 tagttgtatc tccaaataaa gtattatctt tcatatcctc tactaaatta gttaaatttt
    43501 ctctttcttt caataattta tctttatatt ttttagtatc catttttaac acctctaatt
    43561 ttaatattta tatcataaaa atagtatgtg gaaaagtgaa ttaaacatac aataaaaata
    43621 agatttgatt ctaaaaatgg aatgtctcaa aatgaaaatt ttagttcatt taaccctctt
    43681 ttttatctga aatcaaatat atttttatcc tttcaacaat gaaaaagaga cttatctcta
    43741 ttttgagata gtctcttctt tgaacataat ttaaatataa ttttttaatt tttatagtta
    43801 ttattttact aacttgccaa tttatgatta ttttgttctt taatatgttt tgctttttta
    43861 aagaataaaa gaccaagaat tattgctaca ataacaccta ttccattaga tatattaact
    43921 ggtagtctaa atccttcttt tgcttgcatt atataactaa atgttactac agtcataaaa
    43981 agtgctggta atgtagttat ataatggttt ttatttgctt tgactaaata tgcagaacca
    44041 gtccacaaca ttatcattgc aagtgtttga tttgcccaag agaaatatct ccaaattata
    44101 ttaaaatcta taaatgtaag agcaacacca actgcgaata atggtaaagc tattaaaaat
    44161 ctatttttga ctgcatcttg attataattc attgcatctg ctattgtcag cctagcactt
    44221 ctaaatgctg tatctccaga agttatagga catgccacaa ctccaagtat agctaaagct
    44281 cctccaatag gacccattaa tccaacagat actgtattta ctactgttgc tgctccacca
    44341 tcattaaata tcacattaag ttgaggtatg ccatggaaat atgacatggc tgctgctgcc
    44401 caaactaaag ctattatacc ttctgcaacc attgacccat aaaatactgg tcttgcctca
    44461 ctctctttct caacacatct cgccataagt ggtgattgag ttgcatgaaa acctgatatt
    44521 gctccacatg ctattgttat aaataagtat gggaataaag gtgttccatt tggattcata
    44581 ttttgtaaat ttatatttgg tatgttatac ccctttatta ttaatcctcc agctacacct
    44641 actgccataa ttaataatgc tgctccaaat aaaggatata ttttaccaat caatttatct
    44701 attggtaaaa cagtagccat aatataataa agtattatca ctccaaccca tatttgtgcg
    44761 tttacacctg tcaatgtctt taataatcct gctggacctg ttacaaatac aactccaacc
    44821 aatactaaaa gaataacact aaatattctc attgctattt ttgcaccatt tcctagataa
    44881 aggcctacca actctgatgc agatgtacct ttgtttttca ttgatagata tcctgaagca
    44941 aaatcgtgta ctccaccagc aaagattgtt ccaaacacaa tccataaaaa tgctgatggt
    45001 ccaaataatg ctccttgtat agctccaaat atcggaccta accctgctat atttagaaac
    45061 tgaattaaaa agattctctt ccatttcatt ggcacataat ctactccatc cctacaagct
    45121 atagctggag tttgattttt gtcattggtt ccaaaaacct tttctacaaa agtaccatag
    45181 acaaaataac ctactataag tactactatt gaacctaaaa agcttaccat aaattcatcc
    45241 ccttagtttt tatataattg ctttataaat ttttatgagt ttaagaaaac tatttccagt
    45301 tcaaatagta atactttttt atgctaatat aaatattaat tacattaagt gcatatttaa
    45361 gtacatgaaa tgactttata tatgcattaa cagcctaaat tcttttactt tgcttctact
    45421 tacagttact tcataatcac tattttttaa ttttaatatg tatgtattat taaaccatgg
    45481 tataatttct tttactttgg ttaagtttac gatataagac ctatgtgttc taaaaaatgt
    45541 tttatcattt ataagatttt cgacttctga tatgccttct tttaatataa acttttcttt
    45601 ctcagtatat ataaatgtct gcctttcatt agcttcacag taatatatat catcaatatc
    45661 tattacaact aatttatcac ctttccaaag gctaatttta tgtgttattt cttctatctc
    45721 ctgatttact gcttccttct tatatttgta taaattacta tttacattag atagttcaat
    45781 atcactcatc tcactttttt ctaatttatt cagcatagaa ataattctct cttcagaata
    45841 tggtttcaat atataatcaa atacatccaa agaaaaagca tctactgcat aactttcata
    45901 tgctgttata aaaacaattt taggtcttga tttaaactga tttaatgttt ttgcaagtag
    45961 cattccatca agatgaggta tatttatatc taaaaaaatt acatctattt tattttcctg
    46021 aataaagtct aacacctcta taccattggt aaattcactt actacctcta ttccactttt
    46081 attttcaata aaatatctca attcctttct tgctggaaat tcatcttcca ctattatagc
    46141 tctcatactt ctactccttt acataaaata ctatcaaagt cccattatct attcttctta
    46201 tattaagccc tcttccatac atcagtttaa gccttaaatg tacattataa agcccaatct
    46261 tattttctgg catattatct tgatatacat tatttataat ttcctcactt atacctatac
    46321 cattatcctc tattgatatt ctcacagtat tttctaatga atacggtaac ttttttatgg
    46381 atattttcac tacaccagct ctaccacttt ctaaaatacc atgtattatt gcattttcca
    46441 ctaatggttg tataatcaaa cttggaatct ttatatttac atcttctata tcataagata
    46501 cagttagtaa ttctccaaac ctagcttttt ctatctctac aaaagattta acttgttcaa
    46561 tctctttatt tatatcaatt aagttatcac tatattcaag attatatctt agataagttg
    46621 ataaatttat tattaactct ctagccttat ctggactaaa tcttataaat gaagctattg
    46681 tgtttaggga attaaacaaa aaatgtggat taatttgtct ttgaagtgct tttatttctg
    46741 ctttatttct cgcttctata tcttttttat ctttctcaat cccctctact atagatataa
    46801 caaatcctat tccaatctgc ccaactatta aaggtaaata tattccaccg attatttgaa
    46861 ttgctaaaga atgtggatat gatattaagt atataagtaa tatagtaaaa ctttcagaaa
    46921 tcatgcctac caatattcca tacattactc tatgttgttt tggtatcctc ttatatagaa
    46981 atcctgataa tacacctgct agtatacttg ataaaagaca tggaacagat gttatccccc
    47041 caatatccat aaaatatcta tgaatccctg aaaaaactcc tgctgtaata cctaccattg
    47101 gaccaaataa aatgccacct gatactatag atattattct agtgtttact attgacccca
    47161 tataatttat accactataa gttccaaata tggctaaaaa agtaaaaact aatgctatac
    47221 agaccaagtc attaaaacta tattcttcct tttgaaatat ctgcttaaat atttttaact
    47281 ttgttattag aagaaacaat actacaataa ggcttgtctt ttctattaat gcgattaaaa
    47341 ttgatgtttt cataatcccc ctttaaaaaa taaattttta cacactctaa atttattatg
    47401 gttgttataa attacatatt tgaagtaatc ctatcacaaa actttccaca tttaatcttt
    47461 taattaaata agaaatagtt gtacttctat taacaactaa tactagctag cataagcttg
    47521 taataacttg tagttattat taactttaca attctagtat ttaattttat actttagaaa
    47581 tctcttttct tagaaataat actttcgaat atcatataat acaatattat gtagattctt
    47641 actcatacaa catatttctt taaaaatttt atactattct ttgttcaaat atctcatttg
    47701 atttaattgt gttaaacaca cattatcatc tctctgttat atatttatta tatagccgta
    47761 tatcgataaa gtaaataaat cccatattta aaataatatg tttgacaata aattattata
    47821 atgtatattt accataat
//
LOCUS       DAEQAF010000017        47829 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.018, whole genome shotgun sequence.
ACCESSION   DAEQAF010000017 DAEQAF010000000
VERSION     DAEQAF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 47829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47829
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.018"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(123..1724)
                     /locus_tag="KRN00_001113"
     CDS             complement(123..1724)
                     /locus_tag="KRN00_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1826980.1"
                     /translation="MIYDLILKNGFIIDGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     YDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGIDGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYPRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(1835..2512)
                     /locus_tag="KRN00_001114"
     CDS             complement(1835..2512)
                     /locus_tag="KRN00_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1826981.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2525..3220)
                     /locus_tag="KRN00_001115"
     CDS             complement(2525..3220)
                     /locus_tag="KRN00_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH1826982.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3272..4471)
                     /locus_tag="KRN00_001116"
     CDS             complement(3272..4471)
                     /locus_tag="KRN00_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBH1826983.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSIL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4732..6777)
                     /locus_tag="KRN00_001117"
     CDS             complement(4732..6777)
                     /locus_tag="KRN00_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1826984.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7188..7997)
                     /locus_tag="KRN00_001118"
     CDS             complement(7188..7997)
                     /locus_tag="KRN00_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1826985.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8081..8614)
                     /locus_tag="KRN00_001119"
     CDS             complement(8081..8614)
                     /locus_tag="KRN00_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1826986.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8764..10113)
                     /locus_tag="KRN00_001120"
     CDS             complement(8764..10113)
                     /locus_tag="KRN00_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH1826987.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMLIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEVIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(10125..11507)
                     /locus_tag="KRN00_001121"
     CDS             complement(10125..11507)
                     /locus_tag="KRN00_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBH1826988.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNKDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGVEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDRPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            11751..12965
                     /locus_tag="KRN00_001122"
     CDS             11751..12965
                     /locus_tag="KRN00_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBH1826989.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDVKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            13142..15055
                     /locus_tag="KRN00_001123"
     CDS             13142..15055
                     /locus_tag="KRN00_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1826990.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYKNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFDDIIHASEK
                     TKDCIEFAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKVSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            15326..16300
                     /locus_tag="KRN00_001124"
     CDS             15326..16300
                     /locus_tag="KRN00_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH1826991.1"
                     /translation="MHILKSVKKIPGGLMVCPLLLGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            16321..16596
                     /locus_tag="KRN00_001125"
     CDS             16321..16596
                     /locus_tag="KRN00_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1826992.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            16609..17772
                     /locus_tag="KRN00_001126"
     CDS             16609..17772
                     /locus_tag="KRN00_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1826993.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYVVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            18109..20388
                     /locus_tag="KRN00_001127"
     CDS             18109..20388
                     /locus_tag="KRN00_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1826994.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSVVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMLRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRTLCNKYNIPTKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKTLEETNMDSFS"
     gene            complement(20483..21823)
                     /locus_tag="KRN00_001128"
     CDS             complement(20483..21823)
                     /locus_tag="KRN00_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1826995.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAENILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCILNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGININLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(21835..22617)
                     /locus_tag="KRN00_001129"
     CDS             complement(21835..22617)
                     /locus_tag="KRN00_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1826996.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(22632..23654)
                     /locus_tag="KRN00_001130"
     CDS             complement(22632..23654)
                     /locus_tag="KRN00_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1826997.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGQRNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(23660..24673)
                     /locus_tag="KRN00_001131"
     CDS             complement(23660..24673)
                     /locus_tag="KRN00_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1826998.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(24801..25739)
                     /locus_tag="KRN00_001132"
     CDS             complement(24801..25739)
                     /locus_tag="KRN00_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1826999.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            26009..26473
                     /locus_tag="KRN00_001133"
     CDS             26009..26473
                     /locus_tag="KRN00_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827000.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILSGTKTMVIRGAAGRKIPHSRVF
                     ENELLYFMEKGTGKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITSLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(26585..26902)
                     /locus_tag="KRN00_001134"
     CDS             complement(26585..26902)
                     /locus_tag="KRN00_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1827001.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(26915..27646)
                     /gene="chbG"
                     /locus_tag="KRN00_001135"
     CDS             complement(26915..27646)
                     /gene="chbG"
                     /locus_tag="KRN00_001135"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBH1827002.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKSVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(27672..28982)
                     /locus_tag="KRN00_001136"
     CDS             complement(27672..28982)
                     /locus_tag="KRN00_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBH1827003.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(29059..30372)
                     /locus_tag="KRN00_001137"
     CDS             complement(29059..30372)
                     /locus_tag="KRN00_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1827004.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(30394..30705)
                     /locus_tag="KRN00_001138"
     CDS             complement(30394..30705)
                     /locus_tag="KRN00_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1827005.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(30905..31609)
                     /locus_tag="KRN00_001139"
     CDS             complement(30905..31609)
                     /locus_tag="KRN00_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1827006.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(31700..33061)
                     /locus_tag="KRN00_001140"
     CDS             complement(31700..33061)
                     /locus_tag="KRN00_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1827007.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAVYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            33560..34714
                     /locus_tag="KRN00_001141"
     CDS             33560..34714
                     /locus_tag="KRN00_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1827008.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRNAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(34796..36514)
                     /locus_tag="KRN00_001142"
     CDS             complement(34796..36514)
                     /locus_tag="KRN00_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH1827009.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLFTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(36519..37508)
                     /locus_tag="KRN00_001143"
     CDS             complement(36519..37508)
                     /locus_tag="KRN00_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1827010.1"
                     /translation="MSYLKINNVFKSYDQKKVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(37604..38653)
                     /locus_tag="KRN00_001144"
     CDS             complement(37604..38653)
                     /locus_tag="KRN00_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1827011.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(38930..39598)
                     /locus_tag="KRN00_001145"
     CDS             complement(38930..39598)
                     /locus_tag="KRN00_001145"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBH1827012.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(39604..40977)
                     /locus_tag="KRN00_001146"
     CDS             complement(39604..40977)
                     /locus_tag="KRN00_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBH1827013.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(40974..42752)
                     /locus_tag="KRN00_001147"
     CDS             complement(40974..42752)
                     /locus_tag="KRN00_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBH1827014.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEMHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(42869..43192)
                     /locus_tag="KRN00_001148"
     CDS             complement(42869..43192)
                     /locus_tag="KRN00_001148"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBH1827015.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(43179..44156)
                     /locus_tag="KRN00_001149"
     CDS             complement(43179..44156)
                     /locus_tag="KRN00_001149"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBH1827016.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(44171..44734)
                     /locus_tag="KRN00_001150"
     CDS             complement(44171..44734)
                     /locus_tag="KRN00_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBH1827017.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(44786..45277)
                     /locus_tag="KRN00_001151"
     CDS             complement(44786..45277)
                     /locus_tag="KRN00_001151"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBH1827018.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(45280..47205)
                     /locus_tag="KRN00_001152"
     CDS             complement(45280..47205)
                     /locus_tag="KRN00_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBH1827019.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKNKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVIFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(47207..47518)
                     /locus_tag="KRN00_001153"
     CDS             complement(47207..47518)
                     /locus_tag="KRN00_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827020.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
BASE COUNT        15967 a         8348 c         5914 g        17600 t
ORIGIN      
        1 taaaataaat attaatacta taaataaaaa cgaagcatga tttttattta aataaatctc
       61 aaacttcgtc tttacttact tagatattta tttactttct aaatcctatt atttttaaaa
      121 ccttatcttt ttaatacctc accacattta ttctcagtaa tctctccatt ttccaatgca
      181 atttttccat ttacaattac atattcaaca ccattggcta gtaattgtgg ctttgaaaaa
      241 tcaatatctt ctgacctagg ataactatag ttatccatgt caataactgc tatatcagct
      301 atcaaccctt ctttaagaat acctctattt tttattttaa attgcctagc tggtaatgaa
      361 gtaactcttc ttacaatctc ttccaatcta acaccagact ttctgtacat attgaagaaa
      421 attggaaaag ctcctcttct ttgtagttca aaccatgaca tatccccacc cacactaaac
      481 aaacaatctg aaccaaccat aacaaatgga ttatcaatta ttttatcatc atgtagttta
      541 tctgggaaat cagctctata cattcctcct aaacaaaaga taagttcttc gtctccatct
      601 aaaagtaaat cgagtaataa cttgtcttca tctattcctt tttgtgtagc tatttcacgt
      661 attgatttct tttccatatt aatatcttta gtgtttagaa gtattatact ccccctatct
      721 ccaagtataa atgcttcttt taatataagt gttcttccct cttcatttct aagagcatcc
      781 attaccccat ctatacctaa ttcaaataga ctagatgata ttgccataat aaattgaatt
      841 actctttttt tcttcataca atgcccagaa cttcttggta ctgtgtcaac cattatttca
      901 acaccattat acctagcctt taatatctca tcaaatgctt ctatttcaac tggacttaag
      961 tgagatactt gaaccctagc accacttttt tgcccaacct ctatggcttc ttttactgca
     1021 ttatatcttc ctatgtaatc tctaatatga gatgtatata taccatcata ctctttaatc
     1081 tgccttgcaa tatcaacaag ttcatcaata tcagcatact tacttggtat atatgccaat
     1141 ccagtagata ttccaaaagc accacttttc attccatcat ttattatatc tgtaatttca
     1201 tttttttcct tttctgtagg aggtctatcc ttagaacctc ccataacact ccatcttata
     1261 gtcccatgcc ccaacaagaa tcccatattg acagaaatac cacttttaga tataaggtca
     1321 caatattctg taaaattatt ccaacattta tttttatcta taagatactt tttttcttct
     1381 tcaagtaata gaccattttt atacatatat tcatacacat tttcagaaga atatggtgtt
     1441 atagaatgtc cacaattacc atttatagtt gttgtaactc cttgttttag aaacttttca
     1501 aatttaccat ctagtattgc tactatttct tcatgaacat gagggtcaat aaatccaggt
     1561 gttataactt ttccacaaca atcaatctct ttatttgtat tgctatttat cttagaatct
     1621 atttttgcta ttaagttgtc tttaattgct atatctccat aaaaaccagg attacctgta
     1681 ccatctatta taaatccatt ttttaagatt aaatcatata tcaaaatatt ccctccttaa
     1741 aaaccaattt ttaaataatc ttaatgtaat ttttatattt gaaaatcaaa ttattatatt
     1801 tcatatttga aaattcacta ttatttcatt gtaattagtc actaagctta tctttataca
     1861 tagctcttgc aattaatata gtaccaaata cacatataag aactactaga gactgtggta
     1921 ttataccttg ctttgataat ataatagtca atacagatat tacaattgct actagaccta
     1981 attttttatc ttgtaaaaat acttgtccaa aaactgaccc aaatagagct ggtaaaatta
     2041 agtttaattt ttctactact tcagctggaa ttttagatag tacgcttcct cctaaaatta
     2101 cccctatagt tagtatactt atattcacta aaatagatac agctattcct attgtagata
     2161 ttatcgagcc ttcttctgta cctgattcaa cttctgctgc cttttgagct gctattgaac
     2221 atggtagcct catattagat atattaccag aaagaaaact catataagtt cctggtatac
     2281 ctaagattgg tgaataagaa actggttcta ttatgtaatt tggagcactc atactgacaa
     2341 ttgccattgt acttgctaat aatgctgata ttggaggcat aataccaaat ccaaagctca
     2401 aaattattcc aggaactaat gctgctataa tacccaaaga tagtgttagt cttccatacc
     2461 ttatcataaa aggtaaatat tcttcattgt atatagattt tactttactc ataaaactcc
     2521 ccccttatat tactgaagct attatcattc cgctaaacat tgatattgta agcccccact
     2581 ctcttaacca ttttatattt ttcttctttt caagcataca caatattacc attatagcca
     2641 ttccacttat acatgcaatt gttccattat caaaacgcaa caccctatca gcatttagat
     2701 atgcaaatga acccaacatt gctcctagag atattattgg tataaatgat ttcttgccac
     2761 tagatataac attggttatc ttatctagtt tatgtccaaa tagtaatgtg aatattatcc
     2821 atcctaaaga acctaatatc atagtccaaa ctgcatttgt aaatgcaagt tttgtcattt
     2881 caggagaacc taaagttata cctaatgcat ctgttccaaa tccggctgac attgattcaa
     2941 aaattacaga acctataaat gataatctca tccatgctat aggcccaccc atagttacta
     3001 taagcgatac cattccagca aatatagtca ttgaaggccc aatagctgaa atagcactac
     3061 tcttaacagc tgactttatt tgtttatctg ttattcccat tgttttacca actttgcaag
     3121 attttatagc aaatataagg gattgtacca ctactattga tactgctact gtactcgcta
     3181 tccacaaaag tggatgatta gctaatttta aataatccat ttataaaacc tccctataaa
     3241 tcctcaaatt ttattaatat ttctaatata tctatttcca aacctgtttt agtactctaa
     3301 gtatatttcc acctagtacc ttctctattt cctcatcact atatccatgc tttactaaat
     3361 atctgacaat gttttttgaa gtttctgttg ggttctcaag accttttaca tattctactt
     3421 tgggatgttc ttttgttcct gttatttttt ttatatcaaa tttagcagct agtattgagt
     3481 gtaattttac atggtcgcca tatactgtat ctggtccaaa agctacatgg tctattccta
     3541 ctaaattttt aatatactca aaatgttcca taaatgactc tattgaatgt tctttattct
     3601 tctctgttat tgtagtatga ggtgctgctt ctacacctat aacccctcct tttttagcac
     3661 atgctattaa tacttcatct ggagttagtc tctttgtgtt ccataaactt cttgccccaa
     3721 catggcttaa tattattggg tccttgctat attctattac atcaagtgta gtttgaactc
     3781 caacgtgaga gcaatctatt gccattccaa ttttattcat tctttcaaca gcttttttcc
     3841 caaaatttgt aagacctcca tctttctctt cttttagtcc tgaacctaat gcattggatt
     3901 cgctgtatgt tatacccatt aaccttatac caaatccata cagtatatct attctatcaa
     3961 gttcattttc tattggtgct gcaccttcta atgttggtat caatgctact ttaccttcac
     4021 ttttagctct gtatatatct tctacttttt cacactttat gacaaaatct tgatgagcta
     4081 aatcacatag tctcatgcct aaatctatta atatatcatc ccatttccac cctgaatttg
     4141 atgttatcgt acatacacca tccattaaat tatcaaatat agcatcataa tatcctcttg
     4201 ataatgcttc ataagcgcat ctttgtttac cttccctatt atattcaaat atatctcttt
     4261 ctaggtgttc tggaaataat actggatgtt catgtaatga tataaatatt ttttcatcca
     4321 ctatactttt aaccttagct tcttgaatat catctaattc aataaggtac tctttaactc
     4381 ttttatctcc tttacacatc tcaatagatg aaatatcttt tcctttttct aaataactat
     4441 aggcttcata tcctttgtaa gctgacttca taacaacacc ctccaagttc tacaattttt
     4501 tatatttttc ctatgtagca attgatgtgc caaaatataa attttaattg tataataaat
     4561 cttgcaaaaa ataaaaacag tagtaaggtt gatatttact actgttttat taaaaataat
     4621 cttcttagat tatttattca atatttttga attatcttaa tcttaaagat aattttattt
     4681 atttctatcc attataggga tttttttagg gtgttttgcc tttttagtcc cctatatcac
     4741 tcccttaatt tttacatatg atataaagtt ctttccttca tcagttataa aactaccttg
     4801 tttttttact ccagataaaa gtaaaccatg gctctttaac ttatctattc tttttctaat
     4861 ttggtctaca cttaaaacta tatctttttc ttttaaaatc tcttgcagtt tatttcttcc
     4921 taataatata tttttattat tccaagtttc tatactggtc aatatacata tactttcctc
     4981 aaagaaatta gattgtttga aatctaagat aattgaatcg aaattttcat taactaaagt
     5041 attgtttttt tcaaatctaa attgttctgg caaatgctcg taatctactc tatcttcctc
     5101 aactatagta tcaatataat aaattaaatt tttaagctct cttacatttc ctggccattc
     5161 atacaatgtt aaagcttgca ttgattcctc tgtaaaacat ttgttgctat ttatttcatc
     5221 taaaaaatac ttacttataa gaggtatatc ttccttacgt tctctaagtc taggtatctc
     5281 tatatgtaat acattaatcc tataatacaa atcttctcta aaggaacctt ctttaatttt
     5341 tttctttaaa tctttatttg ttgcagctat aattctaaca tctattggta taattttact
     5401 tccgcccatt ctcataactt ctttttcctg taatactctt agcaatctct gctgtacatc
     5461 taaagatata tcacctatct catctaaaaa aattgttcct gtatgtgctc tttcaaatat
     5521 acccattttt ccacctttta ttgctcctgt aaaacttcct tcatcatagc caaaaagttc
     5581 actttcaata agtgtatctg acaaagaaga tagattaact gcaacaaatg gcttgttttt
     5641 tcttagagat tcattatgta ttgcctgggc aaatatttct tttcctgttc cattttctcc
     5701 aagtatcaac acagaaaagt ctgtagttgc tatttttctt gcaatattaa ttttttcttt
     5761 tattatttta ctctcaccta caacactctc aaatgtatac tttgatacaa aaccttttga
     5821 ctgaagttta ttttgaatct tgtcctcaag cacttgaatt gcacttatat ttttaatgct
     5881 tataatactc tttattcgtt cattattttc ataaacattt actttattaa ttatcagttt
     5941 tttgttattt aaatttacta cttcatcatt aacttcatct tcttgaaaaa atattttttt
     6001 gacaacctta tcactaaata agtccataaa gttattagat ataatttcat tttggtctat
     6061 tccaactaga ttagaaaata ctttgttgca atatataaat tttcctaatt tatcaacaga
     6121 agcaatacct tcatctataa tctccaaaaa actcttcatg gttttattca tagttgtata
     6181 atacctatat ccacttactg tatcttcatt gtatttttcc ttaataatat gtaatttatc
     6241 tatagatata tttagttttg taaagatttc tataactgta tttatatcaa ttaccttatc
     6301 acctatgtca attatttgct ttatgttttg tggtatgctg tttctgcttc ccgtaataat
     6361 tccaatctca catttagact tatcacaacc tggataatat ggtattagat taatatgaat
     6421 taatcctagt tttctaatta tcttggcagt ttcatctgct gactctttat aagcatctat
     6481 aaccataaca tcagaatcat tttctatact tattatctga tttatatttt caatatttat
     6541 agtacgatgt actattacaa taggtatatt tttatcaata ttattatgta tatattcctt
     6601 tatatcattg tctgaacata ctacaagctc atagcttgat agttcaatat ttatcctatt
     6661 tacatatacc aagttatcta tattacaaaa ttctccaaat atattttcca attgttttga
     6721 tatatctata tttattttgt catcagttga tacaaataaa atattatgtt ttttcatagt
     6781 cccacctcct gtttaacgag tatagaaagt aataatttgg tctattgtag cactttttaa
     6841 aaaagtttta aatcttaaaa atcaaatttt gtaccattta ctattatttt ccataataaa
     6901 ataatgtaag ctatcttttt tcacatataa tttaatttct aaaacggtta gtttgacatt
     6961 attggaatat aaataaaaat ttaatataaa ttcgttaata tattaataca tttttaagaa
     7021 tgacaaggaa taaattataa caaattttag gaatatataa taatagggtc tcagaactta
     7081 gttacaagtt ctaaaaccct atttgtttag tgtaaaaaac atcataaaat ttagcttaaa
     7141 tcttttcaca taatattact ctttttctaa gtgataataa aatatatcta ttcctctaaa
     7201 aactgtaaaa attcctgatt aaatagttta agctcatcat agaatatagc atgaccacta
     7261 tactcaaaag tatataaaat tgaatcttct attttttcat tcataaaaac tgcaaattca
     7321 tacggacata tttcatctaa tttcccatga aatataccag taggcactct tacacatttt
     7381 aaatcattaa ataattcttc atctcttaaa gatacagcag ttccaatagt gccaatacct
     7441 gatgcactaa aaccaatatc attaaaccat cttctaaagc tttctggtgg atttgatgca
     7501 aatacttttt cgccaaaatc ggttaccatt tctggtctat cagtacatgc ttgtgctatc
     7561 aatttattta catcttcacg tgtcatacca tatggaaatt ctggaggtct ttgtacaaat
     7621 gatggtgcag cagctgcagc taataccaat tttgacactc catatccatt aaataaactc
     7681 atatacctaa gtacgattgc tcctcccatt gaaaaaccaa caagggtaaa gtcttttaat
     7741 ccaatagcat gtaccacctt ataaatatcg tctgctaatt ggctataagt atatcctcct
     7801 gatgttgcat cagatttacc aaaacctctt aaatcaattg aaactgttct atatccgagt
     7861 tttggcaata tatttgtttg atattcaaat atcttatgtc ctaagggcca accatgtata
     7921 aaaagtacag tttttttagc actcggattc aaatcatata ctgctatgtt tatatcattc
     7981 acatatacat aatacatatc aacagcaact cccttcaaga aaatgtatga tggttatttt
     8041 atatatatga ataaaatgat gaataactaa attttcaaat ttatttacaa tacttctcta
     8101 ttgccttttc aaataaactt acatgaagtt tttcatctag gattattcta tttaatatag
     8161 cttttatata agggtcttca ataagactta tatctttata ataattatta atagccacat
     8221 gctccaaatg caaatctagt tttaatctgt tacaaataga atttccataa catacaaaac
     8281 caccattcca atatgcacca caagaacttg tagaacctct atatacagga tttccaccca
     8341 ataatcttat agtctttgct aatatctcca tatgtaacat ttctgttata gatatattta
     8401 tccacatttc acttaactct ctatgcgttt catctaaatc aaaattatgg tatagatatt
     8461 gatttacact cgtaaattca cttgatactc cggcatagtc atccatcaat aattctgcat
     8521 aatacttatt tggacctaaa acttttatct ctggatatgg ctcatcactt gaatatccat
     8581 ttcgcttgtg catgtcataa tgtgcatcac tcataatatc tcctccttta aatttaatac
     8641 atgatattaa ttgtatgcat cacgactttt tcatataact tagataataa aatctactta
     8701 aataataaaa agccatatta attaaaatta acatgacctt ttatccacaa aattactttt
     8761 taattattca tcttttccag ctactgatag ctctttaata acaactgaag gcgaacctat
     8821 actactcatt ggaaattcta aatcttcccc tataacttca atatctttta acaggtcaaa
     8881 atagtttcct gctactgtaa tttgctctac tggaaatact ttttttcctt ctttgatata
     8941 aaagcctttg gcagctaaag aaaagtctcc tgttactgaa tttgcacctg aatgaagtcc
     9001 tgcaaagcta gtaaccatca atccttcatc tatatccttt ataatttcat ctaaagattt
     9061 atctcctttc tctatataaa aattagttgg atatatgctt ataggtgatg aatatgaaga
     9121 ttttattcca tttcctgtag tctttacacc tgccttatta gccgttttta agttatgaag
     9181 taaagttata agctttccat ttaaaacaac ttctttttta aatgtagcta ctccttcatc
     9241 atcaaaagga gtagatgcca taccattttc taaaagtggg tcatcaacta ttgtaactat
     9301 aggagatgct atcatgtctc cttctctatt tttcaataaa gataatcctt tttgagctga
     9361 atctgcatta aatatcccag aaaatgtgct aagcaaagat accatagctt cattaagcaa
     9421 tatagtttta tatttacctg atggaatact cttaccacct actttagata aagcattatc
     9481 aacaccaagt tttgctatct cacaaggttt tatttcttca atagaatttg ctatattata
     9541 tcctattcca tcatattttt gtccattgtc ttctatgata ggaactacaa accctataag
     9601 catattagtt ttattgctta aattaagacc tttagtatta gatataccat tacttgatac
     9661 agaataagat atagtacatt tagataaatt taccacctta tctgaataag ctttagtctc
     9721 tctttccatt tctaaagcta aatcaatcaa cttatctgcc tctaaatttt ctagctcttt
     9781 agaataagtc tttacatcat tatagtgctt atctccttca tatataaatt gtacatcttc
     9841 attttcaata gtgtttactc catcttttac attttttatc aacatatcaa cagctttatc
     9901 atctaaaatt tctgtataag aataacctat ctttccattt accttacctc taaaagataa
     9961 accaaaagat ttatcaagat tgtatttctc aacttctcct tcatatatat ttatacttaa
    10021 attttctcct gtataataat atatttcaca ctcttcaaaa ccttcactta gagccttttt
    10081 aaataatata tctttaaaat ttttaagttc cacaattatc cctcctatct tccacctaca
    10141 gtaatttctt ttacccttat cataggttgg cctacattag ttggtatact tcctgatgat
    10201 gagccacaca tcccctgagc ttgttttacg ttattcccaa ccatatctat attcataagt
    10261 atatcgctac cttttccaat taaactagca cctctaactg gctcttgtat ttctccattt
    10321 tttattaagt aaccttctga aactgcaaaa ttaaactctc ctgttacagg atttacagaa
    10381 ccaccaccca tttttttagc ataaagtcca tctggtattg actttataat gtcttctggt
    10441 ctatcctctc cagcagcaat ataagtgtta gtcatccttg aagttggtgc aaatttgtag
    10501 ttctgtctac gagaacttcc tgtaggattc attcccattc gtctaccatt aagtttatct
    10561 atcatataag acttcaaaat tccattttca atcagtatat tcttttgagt tggatttcct
    10621 tcatcatcta tattcataga accccagtag tttggtattg taccatcatc tatagctgta
    10681 atctttgtgg aagcaatctg ttgacctaat ttatctgcaa atacagagtt cccctttgca
    10741 actgatgtag cttccaaaga atgtccacaa gcttcatgaa atattactcc accaaatcca
    10801 ttatctattg ctaccatcat attacctgca ggacaatttt tagcatgcaa catagtatgc
    10861 gctactctag ctgattcttt tgcataatat tctgggtcta tttcttcaaa tatttcaacc
    10921 cctttacaac ccccaggacc ttcaaatcca gtttgatttt cattaccctt agatgcaatt
    10981 gaacttatcc ctagtctggt tcttattctt ctatcctcaa catatatacc ttcagtgttt
    11041 gcaattaata ttttttggtc tttatccaaa tagctaacac ttacttgaga tatatcatta
    11101 ctaaattctt ttgcactctt atatgcaacc ttcataacac ttactttatc tttatttcct
    11161 attgaatttg gataaatttt tatattatgt atgttattta ttttaatact gtcatttaat
    11221 attacacttt ttccatcttc caatttacct aaagcaacag cagctttgta tgctacatcc
    11281 aacagactat ttaatgaatt gtcacttgta taagcatata tacttttcaa tcctttaaat
    11341 attcttattc ctataccata atttcttcca cctattgcat tttctacttt attatctatc
    11401 aaactaatag aattatttat agtgtcttct tcaaaaatct cagcaaaatc tcctccagta
    11461 attagacatt tttctaatac cttagaagct atattttttg aaagcataaa tttacctcct
    11521 actttaaatt tttaattaac ttttattcaa tctttttact tgttaacaaa cattatatac
    11581 tatattactt aaaataaggt aattatgaat atattataca tatgttttat actaaaatgt
    11641 tatcacattt tatctataca tacccatata actagataat taaaatgtat aatattattt
    11701 gctatagaaa ataatacact catacataat aaattttagg agtgaagtat atgaatcaag
    11761 aatatgtaaa aggaaatcct atttttacta atattaataa agttccaaga caatttccat
    11821 accttactga tgatattgat actgatgtta taattgttgg tggtggcgta actggatgta
    11881 tctgtgctta ctatctagct aaaaacaata taaagtctgt cattcttgaa aaaggaagga
    11941 ttgcacatgg aagcactagc gtgacaactt ctctattaca gtatgaatta gatgacaatt
    12001 tgatagattt aacagaggtt atgactctaa aagatgctct aaaagcatat aacctttgta
    12061 cttcagcact tgaagaatta gatacattta tagaactata tggaaataag tgtgattatg
    12121 ccaaaagaga tactctactt tatactgcca acaaacttga agttaaggct atcaaagaag
    12181 aatataactt aagaaaagaa aatggatttg atgttgaata tattgatgaa tccacaaacc
    12241 cttttagctt tgatgtaaaa tcaggattga tagcaaagaa tggaggacga gaattagacc
    12301 catataaata tagtcaccat ttgattgatg taagtttaaa aaatggtctt caagtatatg
    12361 aaaatacaga agtaaaaaaa gtagatttat caaatgataa ggttactgct gaagtatcgt
    12421 atggatacaa agttcatggt aaaaaattaa ttgtagctac agggtacaat acaagtttat
    12481 ttacaaaaag aaattttgca actaagtcaa atacttttaa tatagcaacg aaaccactta
    12541 aaaacatagc ttcttggaaa aacaacattt taattagaga taactgtgac ccatataatt
    12601 atctaagaac tactaaagac aatcgattaa ttataggtgg tgaagatgta agttttgatg
    12661 atatagaaaa tgaaacttta gccaatgaaa agtacgatat tttagaacaa agattgaaaa
    12721 gtatgtttaa ggatataaaa gacattgaag ttgaatataa atattgtggt tgttttgctt
    12781 caactttaga taatttaggt tttattggtc cagataataa aaataacaat ctatggtatt
    12841 gcttaggtta tggagcaaat ggtatactct ttgcaatatt aggaggtata atgttaagtg
    12901 aattatatct tggcaaacaa aataaaaata tgaaattatt taaagtagat agatttgata
    12961 aatagatatt atatattaaa agactgtaaa aagatgaaac tttataattc taaaagttaa
    13021 ctttgataca gtcttttata atgttccttt taaaaatact ttatttataa ttaaatataa
    13081 agtaaaatgt taaaatataa ctgataaaat ttagtcataa gataatattt aagtttattt
    13141 gatgaaatat ggaggaatta ttatgaagga aatactcgtt attgctccca ctaaaggaac
    13201 ctatgaaaaa tcaattcaca tagttaaaaa aaacaaatat aaaaatattg atgttgtatt
    13261 tggcaatcta aaagaaggta tacctcttgc tgaaaaaagt attaatcatg gtactagaat
    13321 tatcataagc cgaggtggaa cttacaatat gttaaaagct acttacaata tacctatagt
    13381 tgaaattaag gtagatgctt atgatattat aaaaagctac aaagaggtaa aaaattccaa
    13441 cgaaccattt ggaataattg gatttaataa tgtcatctac ggtttcgata ttatagaaga
    13501 aatattgaat aagaaaataa ctatgattga aattgaaaaa gaagaagaaa tttatgatgc
    13561 tatagaaaag tacagaaaga aaggtataaa cacatatata ggagatacca ctgttgcaca
    13621 tattgttaag agacttaatt gtaagggaat attaatcgaa tctagagaag aaaacatact
    13681 tagagccatt caacaagcag aacaaatact cgaagcaacc aaggatgaac aaaaaagaag
    13741 attacagata gaagctatga cagattttgt acatgatgga ataataacag ttgataaaaa
    13801 ttttaaaata acattattta ataagagtgc tgaaaaaata tttggtataa aaaaagaaaa
    13861 tgcactttat cataatgttg tagatgttat cccaaacaca gttcttccac aagtagttga
    13921 gactatggaa cctcaaattg gtgaaataca aaatataggg agtacaaaaa ttattacaaa
    13981 tagagttcca atcattgttg atggtcagat tcaaggagct gtttcaacat ttcaagatag
    14041 caaggagata agttcttttg aacatacaat aagaaggagc ttattaagca aaggtctatc
    14101 tgctaaatac acttttgatg atataattca tgctagtgaa aagacaaaag attgtataga
    14161 atttgcaaaa aaatatgctt gttatgatac tcctatgatt attactggag aatctggagt
    14221 tggtaaagaa ctattttgtc aaagtataca taactatagt aagcgtaaaa atgcaccttt
    14281 tgttgctgta aattgtgctg ccatacctcc atctctaata gagagtgagt tttttggtta
    14341 tgaggaaggt tcatttacag gtgctagaaa aaaaggtaaa gcaggtgtat tcgaactagc
    14401 acatgaaggc acaatcttcc tagatgaaat aagtgaaatc cctcttgaac ttcaaggtcg
    14461 attattgagg gtattgcagg aaaaacaagt tatgagaatt ggtggtgata aagttattcc
    14521 tatagatgta aaaattatct gtgcttcaaa taaagactta aaaaatatga tgcgcaatgg
    14581 tttatttaga caagaccttt attttagaat aaatatacta acattatatc ttccttcatt
    14641 aaaagaaaga aaagaagata ttataaaatt atcagaattt tttatacata aatattcaag
    14701 taaatacaat aaaacgcctt taattatcac tccaaatatt aaaaaggcac ttcttgaacg
    14761 agaatatgaa ggtaatataa gggaattgga aggtatgatg gaaagggctg ttattgtgga
    14821 atcatttgac tcgattttat tagaaaaggt tagcaatgaa tatacaaata atatagttga
    14881 taaagataat agtgattttg aatgcagtaa tttagattta aaaactttag aaaaaaaata
    14941 tatctataaa atttataacg aaaataatag aaatactaca aaaacctgtg aaattctaaa
    15001 gataactcgc tccactctat ggcgtaagtt aaaagaaata gaagatgatg tttaaaaata
    15061 atacatacct atatatatca aaacgtttta tgtttaattt taatacataa gacgtttatt
    15121 tgttttcaat aaaaaataca attatatgat aaaaagaatc tttataagtg aaattctcgt
    15181 caatcatact tttaattata agtaatctac agcatttcaa tcgattatta aaaataatca
    15241 tgataactaa agatacaaac tctatatatt ggcatagtaa ttgcttttat aatacctata
    15301 taaaaatgaa agggagtgat actagatgca catcttaaaa tcagtgaaaa agataccagg
    15361 aggacttatg gtctgtccct tgttattggg agcactattt aatacagtat gtccacaagc
    15421 tcttgaaatt ggaggattca caacatcctt atttaaaact ggtgcaatga gtatacttgc
    15481 tctattttgt ctatgcaatg gagctcaaat caatatcaga caagctggta aaccattgac
    15541 taaaggtata gtacttacag caacaaaatt tataattggt gcagtattag gtattattgt
    15601 tagtaaattt attggaccta aaggtataat tggtattaca cctcttgcca tagttgctac
    15661 catgactaat tcaaatggag gtctatttgc tgctcttgca ggtgaatatg gagactccac
    15721 agatgttgga gcaatatcta tcttatctct aaatgatggt ccttttttta caatgcttgc
    15781 ttttggagta actggacttg caaatgtacc tatagtagca ctatttgcag cacttatacc
    15841 aatactactt ggatttatac ttggtaacct tgatgaagat atacgagaat ttcttgcacc
    15901 tggtacaaca ttattaattc ctttcttcgc ttttccttta ggagcagcat taaactttaa
    15961 tcaaattata actgctggac tacctggagt tgtacttggt ttaggagtta ctataataac
    16021 aggtatgggt gggtactttg taatgaaact tatacgtgca gaacatccag cagtaggtgc
    16081 agctacaggt acaacagccg gaaatgcagc tggtactcct gaagctttag cagctataga
    16141 ccctactcta gctacaatag cagctgtttc aacagtacag gttgctgctg ctattattgt
    16201 tacagcaata tgttgtccaa tgttagtttc ctatctagat aaaagagaaa aaaagaaaaa
    16261 atctattttt aaaacaaata aaaatattga agtaaattaa tacttaagga ggtaaaatta
    16321 atgaatgcaa ttattcatgc aaatgaaaaa gataatctag ttacatgtgt cagaccttta
    16381 gttaaaggtg aaaaagtttc aattgatgga aagtcttaca tagtaaatga taatatacct
    16441 gtctttcata agatggctac agaagatgta aaaaaaggtg atgttgtata caaatacggt
    16501 gaaattatag gaattgcaac agttgacata aaaactggtg actatgttca tgtacataac
    16561 attgaaagta cacgtggtcg tggagataaa aaataggagg aagttaaaat gaaattaatg
    16621 ggttatttaa gagaaaatgg tcagtttggt attcgtaatc atgttttaat tattccaaca
    16681 tctgtatgtt caagtgagac agctacaaga atagcatcac ttgtgcctgg agcaatagca
    16741 atccctcatc aacatggatg ttgtcaaatt ggttctgata tagagcttac agcaaagaca
    16801 ttaataggat ttggaaaaaa tcctaatgtt gccgcagttt tagtagttgg tcttggatgt
    16861 gatggtattc aagcaaaaga attagcatct gaaatagcta caacaggaaa aaaggtagat
    16921 tacgttgtta tacaagaatg tggtggaaca ttaaaaacag tttctaaggg agctgaaata
    16981 gtaagtaaaa tggctcgtga agtatcaaaa gaagtaagag ttgaatttgg tatgagtgaa
    17041 attacattag cacttgaatg tggtggttct gacccaacaa gtggaatagc ttcaaaccct
    17101 tcaataggcg ttgcatcaaa ccttcttgta gatgaaggtg gaagtagcat actaagtgaa
    17161 actacagaag taattggtgc agaacatttg ttggctaccc gttttgaaga tgaagaaatg
    17221 aaagataagt ttcttaaatt tgtaagtgat gtagaaaaaa gagcaattgc tatgggagaa
    17281 gatttacgta gtggtcaacc tactccaggc aataaaactg gtggactttc aacaattgaa
    17341 gaaaagtcac ttgggtgtat gtataaggca ggcaataagc cattcaaagg tgctcttgaa
    17401 tatgctgata ttgtacctcc tgataaaaaa ggattatatt ttatggatac tccaggtcaa
    17461 gatatagatt ctatcactgg tatggtagca ggtggtgcac aaattgtaat cttttcaact
    17521 ggtagaggta ctccaacagg aagccctatt tcaccagtta ttaaaatcac tgggaatagt
    17581 gatacataca acaaaatgcc agacaatatc gatataaatg caggtagaat tataacagat
    17641 ggtgctaaaa tagcagatat aggtcaagaa atatttaatg aaataataga agtctgtaat
    17701 ggtaaacata ccaaagctga aagtcttggt catagagaat ttggcattta cagaatttca
    17761 tctacatttt agattgtaac aaaatatctt ttataaatat aatacttatg tagatacata
    17821 agctaaaagt tctttctaat actataaaaa ttttctatac tgaaaaggaa ctgtatcaaa
    17881 attattttga aaacagttct ttttttaacc tcttttactc aaaatattat aaaataagat
    17941 ttaaacaata aacgtatctt gattaatctc taagaagaca taaataaagc taaatgtaaa
    18001 gtgggataaa taaaatttaa tatctttgta tgaaaagata tttggtataa tatgtctgag
    18061 agaattctta tttgtaaaca aataaaggat ggaggatgaa acaaaagaat gaactttgaa
    18121 aacacaaaaa ataaaaaaat aatagctact ttactattga cactcctttt aatcgtgtca
    18181 ttaacatgtg tcacttttat tatgaatcta aataaagtaa cacataatga aacagaacga
    18241 tatcttgtag aagtttcaca aggtatttcc actacaatta atgtgaaatg taaaagtata
    18301 tttaggacac tatattctat gggagatact tattttgaga ttaatgatag tgaaaaagaa
    18361 gtcaatagat acttatcaaa aaaattaaaa ttatttgaat ttgattggtt aggtattata
    18421 gattctaatg gaaattttgt aagtgccctt aaagatacag gtaatgttaa aggacaagac
    18481 ttttatagaa aagcccttca aggcaaagaa acaattactc ctgttaaatc acaatctggt
    18541 acatatggaa ttttatattc tgtaccacta tacaatggcg ataaaattgt tggagctgtt
    18601 gctgcttgga atactattga tactatgaga aatttattaa gtgtagaaag ctttcatggt
    18661 gaaggatttt cccaaattat cgaccaagat ggaaatttta ttgtaagttc agcaaacaaa
    18721 aatgctccaa aaaatgtggt aaattttttt gacatgatta aacaccaagg aaaacaggtt
    18781 gataaaaata aacttgaaga aatgaaaata aacttaaaaa agaacaaaac tggttctatg
    18841 tattatacat taaatgatgg tatttctaag gcaatgcatt atcttccatt acaagaagaa
    18901 aacttatacc tcctttcagt tgttccaaca aaaacagcaa gtgcacagtt tgatttactt
    18961 ctaaaaaaag caatcttcat caatatttta attgttatac tatttttatt gcttattata
    19021 ttgattatgt ttataaatca aaagaacagg gcacaactta taaaaatcgc ctatgtagac
    19081 tctgtaacta aaggttacag taaagcacgt tttgatattg aagctaaaaa aattatacag
    19141 tcatcttcat cagaaagcta ttcattggta tctataaata ttcagaaatt caaacttatt
    19201 aatgattctt ttggtagtga agcaggagat aaaacattaa agtacataca tgatgtcatt
    19261 agtaattatc tagaaccagg agaattgctt tgtcgagttt ctaatgacca gtttaatgta
    19321 cttattaaaa ctattcctca aaaagaaatt cttaagtaca tagaaaatat caccaatgat
    19381 attaatagtt tcaataaaaa tgaagaatgt aaatatttta tagctctatc tataggtgta
    19441 tataaaattg atgacccaaa tctaccttta gtttcaattc aagaccgtgc aaatgttgca
    19501 cgaaaaaata ataaaggaaa cattggaaat catccacttt atacatgtgt tttttatagt
    19561 gatttagagc gtttaaaaat gattaaagaa aaagaaatgg aaaatagaat ggaggaagca
    19621 ttaaataata acgaatttat agtatatctt cagcctaaaa tcagcctcaa agataatact
    19681 attgtaggtg cagaagcatt agtaagatgg caagacccaa ataaaggtct tataccacca
    19741 gacgaattta ttcctttctt tgaaaaaaat ggttttatta caaaactcga ccactatgtt
    19801 tttgaaaaag tgtgtagtat gctaagaaaa tggatagata atggagaaac cccaataccc
    19861 gtttcagtta atttttcacg tgctaattta aataacatag actttttaga aaaatacaga
    19921 acgctttgta ataaatacaa tattcctact aaacttttag aaattgaatt aacggaaaca
    19981 cttgtatttg aaaatctcca aaaactaatt aacataatag accaaatcca cgaagaaggt
    20041 tttcaatgtt cactagatga ctttggaagt ggatactctt cactcaatat gttaaaagaa
    20101 ataaaagttg atacattaaa acttgaccgc gcttttttta gctcacctaa tgcagataat
    20161 attgctgaaa atcatgtaat agaatctata gttaatttgg caaaaaaatt aaatatgaat
    20221 agtatatcag aaggtgttga aacaatcttg caaatggatt atcttaaaaa aattaattgt
    20281 gatatgatac agggatatgt tttttcaaaa cctctgcctc aagaaatatt tgagaaaatg
    20341 acttttggaa aaacactaga agaaaccaat atggatagtt tcagttaaat aagataaaaa
    20401 acttgtctct ataaaataat tttaatcatt ttataaagac aagtcttttt attttccaat
    20461 ttaattttat tttctaaatt tcttatactc ggcttgtttt aaattccctt tttaagaata
    20521 ataatacgat tatcatagca ataaaatctg caactggctg tgccaaccaa acaccatcta
    20581 aattaaattg aattggaagc acaatgatta atggtataaa taaaataaat tgtcttaaaa
    20641 gagttaaaaa cattgaatgt ttaactttac ttatacactg aaaatacaca ggccctacaa
    20701 tagaaatccc cattataggc aatgtaatta gatttatgtt tatacctctt actgctatat
    20761 ccatcaaatc tgaatcttta ttaaatatac ctacaaatac ttctgggaaa acttgtacta
    20821 ctaaaaatcc aaatgacaat atgacaactg acactatgat agataatatt aaagttttct
    20881 ttgcacgctc atattgtttt gcaccataat tgtatgatat tatagtttgc ataccttgat
    20941 tcaatccaaa cacaggcatc ataaacatca ataaaataga tgtaagtgct gtcatagctc
    21001 caatagctaa atctccacca taaaccttta aagaattgtt tgtaaacatg tgagttatac
    21061 ttatagctac ttccatagca aaaggtgtca ttcctattgc aaataccttc tttactatat
    21121 ctttattcaa ttttaagtta cattttttta gttttaaatt ggacttccct cttataaaat
    21181 aatgtattac ccaaaagaat actactattt gacagagtac tgttgctata gctgctcctt
    21241 ttatacctaa attaaataca aatataaata tagggtccaa tatcaggttt aatatacatc
    21301 ctacaatcat tgtccttgct gctaattttg gattaccttc tgccctaatt gcattattaa
    21361 gagaaaatgc aactaaatta aatatacttc caaccaatat gacactcata tagtcttttg
    21421 cataaaatat tgaatcttta cttgcaccca aaataaaaag tatatcttct aagaaaacta
    21481 atcctaatat agttataatt aaagagataa ttatagataa tgtcaaagca ttacctaata
    21541 tattctctgc ttcttctcta tttctttccc ctaactttat agacaatctt gtgctagcac
    21601 ctactgatac caacattcca aaagctatta ttagagtaaa tactggcata gttacaccaa
    21661 gacctgcaat agctatagag ccaatacctt ccatagaacc aataaaagct ctatctacta
    21721 cattataaag tgaagttacc atcattgcta ttattgcagg tatcgaatac ctaaataata
    21781 aaatccatat tttttcatgt cttaatgctt cttgattctc catgttgtca ccatttacac
    21841 catgtcataa gttatacaaa ttggtttatt tgttcttggg tctgttgcta tttctgcatc
    21901 aatattaaat aattctttta gattatcctt cgtcataaca tcatatgcat caccttcaca
    21961 aactatttta cctttcttaa tacctatcat gtggtcagca aatcttgctg cattattaag
    22021 ttcatgtatt accatgacaa tagttcttcc ttgtttttta tttagttcat ctaataattt
    22081 tagtatctct aattgatgtg ccaaatctaa atatgttgta ggctcatcca gtaataatat
    22141 atcagtttct tgtgccaaag ccatagctat ccatgccctt tgtctttgtc ctcctgataa
    22201 atcttccata tttctatcct taaattctgc aattccagta acttctaaac tccaatttac
    22261 aatctctctg tcttctttac tagaattacc aaatccactt ttatgaggaa atcttccata
    22321 agaaattaat tctgaaacgg taagaccact aggagcttga gggctttgtg gaagtacagc
    22381 catatctttt gctatttctt tagacttctt tttgtagatg tcctctccat ttatatatat
    22441 tttcccacta ttagggctaa taattctgcc tatagtttta agtattgtcg attttccaca
    22501 accattagcc cctattatgg tagttatttt tccttttggt atatttaaat ttaaattttt
    22561 tataatatct gtgtttccat atgatacatt tagattctta gtatttatac agttcataac
    22621 aacacccttt cctaatcatt taccaacatt aaataaataa agtacggcac tcctattata
    22681 gaaactacta tacctactgg tatttctata ggtgctagaa gatttcttga tatagtatct
    22741 gctattaaaa gtaataatgt tcctatcaat gctgatactg gtattaatct tttatgcttt
    22801 ggtcctatta tttttctacc tatatgtgga gctattaaac ctaaaaatga aatactacct
    22861 gctactgctg tcgatacacc agataaaatt actgcatata ttataagtct tcttctttgt
    22921 ttttctacat ctacaccaag acttatagat acttcatcac ccaaatttaa aacatctata
    22981 tatttagatt tataaatagt tatacccata aaaatcacta taaatggaag cacagctatt
    23041 acatatttcc aactggttcc ccaaatgctt cctgatgtcc atgccataac cctattaaat
    23101 tcttgtgttg taaatttcaa ttggaatatc gtcaaaattg aagtaaaagc tatgtttaca
    23161 cctataccaa taagtagtaa tcttgacgaa tttataccac ctttccatgc aagagaatat
    23221 ataagaaatg ctccaaataa agctcctata agtgcaacaa taggcattgt aaatacagtc
    23281 aagttactca taccttcata tacattacca ttcataaggt atatataaac tactacaaac
    23341 aatgcagcac ctgaatttat tcccaaaatt ccagaatcag ctaaatcatt ttttgtaact
    23401 ccttgaagta ttacacctgc tgttgataat gcagaaccaa ccaaaagtgc tattactatt
    23461 cttggtaatc ttaatttaaa tattgcaatt tcatgattac gctgaccctg ccctaaaaaa
    23521 gtctttataa catccattgg ttctatagaa aatgagccca tatttaaact caataaaaaa
    23581 gtgataaaaa taagcaccat taaaattgat ataacaagta atgttttaga atttattttt
    23641 ataatatttt tcatagtacc tatttctccc cctttctaac aaggtatata aatattggca
    23701 ctcctataag tgctgttata gaacctactg gtgtctcata tggaggattt atcatcctac
    23761 ttaatatatc tgtatataca agcaatacag ctcctaatac taaagagctc ggtattatat
    23821 acttataatc tgaacctact attcctttag ctatttgagg aactataaga cctataaaaa
    23881 taatattacc agacactgac acagatgctc cagtcattaa tattacaagt actatacata
    23941 taaatctaac aaagttagtt ttttgtccta atcctattgc cacttcttct ccaagactta
    24001 atatagttat tcttggagcc ataataatag ctaaaataaa tccaatacca ccagctacaa
    24061 atagcaattt tataccttcc cacttcactc ctacaagccc tcctgatatc cagaaactta
    24121 attgttgaga taggttaaaa tacatagata ttgctgatgc caaagaaatt agcaatgtac
    24181 caagagcgac tcctgcaaga gctaatttta cattattaac tcttcctctt gatttagaac
    24241 ttataaaata tataaataat ccacttatac ttgctccaat aaatgcaaac atcattacac
    24301 taaaacttcc atgtataagt tgaggaagtt ttttttgaag taccagtgat atcgaaattg
    24361 cgaatgtagc tccttgtgta attcctataa cagatggttc agctatagga tttctcgtta
    24421 ttccttgcat tattgcccca gaaactgcta aaaaccctcc aacaagtgca gctgctattg
    24481 cccttggaag tctaacatcc tttactattc tcatatttat tccatcttcc atttttatca
    24541 aactatctat aacagttgat agattcatat cttttgcccc aatagttatg gataatacaa
    24601 ttccaaatac aagtacaact atacttacta atatcaacaa ataagttata ttttttttac
    24661 tcagcttagt caattatcct acctcctttt cccttttaat cgtcagtata atatcatcta
    24721 ttaagtattt taattttaag atttattaaa aataggtgtg aaaaatgaat atcattatct
    24781 cacacctact aagttaagaa ttactttgtt aattcatttt taactgattc taataataac
    24841 tcttttccaa ttggattgta tgattgactg aaaaatggag cagcatcaag tattgttaca
    24901 ttaccatctt ttactgctct tatttgagcc cagatagcac tattttctaa atctttttta
    24961 tctgcttctg tagcaattac aactatatgg tctgcatcta tatctgttaa accttccata
    25021 cttaccattg gtagtgttat tccatcctgt tttggcatat tcttaggtct agctaatttc
    25081 atatcatcat tgattagagt acctattcca ccatcactaa ataccataaa ttgacctgaa
    25141 cttgccaaca ctggtaaata agttttttct ccattctttt ctataacttc cttacctaac
    25201 tttgtagctt tttcatcata cttctgtagc caacttttag cttcttcttc tttgtcaaat
    25261 aactttgaaa catcagttaa cttgcttctc cagtcatttg cataatcttt catcataact
    25321 acaggagcta tttcttttaa ttggtcatat attttttctt gtctttgact cattattatt
    25381 aaatcaggat ttacttctaa tatagcttcc atatccatag tatccatcat tgagtgccca
    25441 actatcttta cacctttaag ctcttctctt atgtaacttg gtaatttatc agtttcatat
    25501 gagtctacat ttgctgttgc aacaggctta taacctgcta ataatagttc ttcactactt
    25561 cctgatatat caactatttt tttaggattt gatggtatct taacctctcc tttaacagat
    25621 tgtacaactc ttgtctctga tttatcttta tcctctgtat tcttatctga acatgctgta
    25681 acaagtacta atgtagttat aatagatata aatattgcaa gtgattttat ttttttcatg
    25741 attacttctc ctacttgttt attatactta tatgatattg attatcataa gcacatattt
    25801 attatagcat ttttctattt ttagtcaata ttattttgta aaaggataaa aattcctaat
    25861 taatcttaat tatatatagc ttagataagg ttttcttata ttaaacagta tttttttaaa
    25921 gaattggaca caaatacaat gacttttcag ttaaacaatg ataaaatgca atttatagat
    25981 aatgaattta gtagggagga ttcaaaacat ggtacattta gtatattgtg ataatgcagg
    26041 aaaaaaagga gaaaaggtct tagataaaat cttatcagga acaaaaacaa tggttattag
    26101 aggtgctgct ggtagaaaaa taccacatag tagagtattt gaaaatgagt tactttattt
    26161 tatggaaaaa ggaactggaa aaatatctgc aaaagccact gttaaaaagg tagaaaacta
    26221 tgttaaatta acagaagatg aaatttctaa aattttaaat gaaaatcaac caaaattaaa
    26281 tttatctgaa aagcaaaaag ttcgttggca taaaaaatgt ttatgcttag ttgaatttga
    26341 aaatgttgaa gaaataacat ctcttgattt tgaccatcaa ggaaatatgg atgattggct
    26401 tattgttgaa aaaattgaag atgtagttgt tggtactagt ataccttaca attatgagaa
    26461 gtctaaattt taaagtatca ataacataat actatattgc taaactctac ttaaataaaa
    26521 aaagagtgca tttaataatt ataaaaatta tttttataca ctctttttta ataataattt
    26581 taaattactt actttctaat ctttcatata catctataaa ttcttctgct aattgttgaa
    26641 aattcatagc tgtcattaaa tggtcttgtg catgaataag tataacactt atttcagttt
    26701 tattaccatt agcttcattt tgtatcaatt ctgtttggaa tttatgagct ttatgaattg
    26761 attctttcga cttttcaata cattctctag ctttatctat attcccgctc tttgcttctt
    26821 ttattgcttc aaatgctagc cctttcgcat cacctgcaaa tccaattatt ccaaaagata
    26881 tctctatcat cttctcatcc atttattcga cctcctaaat atctctatag cttgatatga
    26941 ctaatccatt cttttctaaa aattctttga cttttttaga tgtaagtatc ttgtgctctt
    27001 tcgttctatc aatagcataa gatgtagaat ttaaaatata atcatctaaa aaagctgggt
    27061 gagacataat atccactaca tcatacttca ttatttcgtc tatatttttt ataaaatatt
    27121 cttcacttac attttcctta taaaaactat ctattaaagg aactacttta gaatactcta
    27181 aattatattc aaatccacct cttatcggaa gattatactt ggttacaatc ttctctatta
    27241 ctgactttaa acttactaaa gtatggatat gatggtgact atctaaatga gatatatcta
    27301 ttccaagccc ttttacccta tctatttgag cacaaagttc tctataaatc tcatcacaat
    27361 ccattttttc aataatttcg tctgtaatcc tcctaataaa aaaaccgtct ttatcaacaa
    27421 tagtttttaa gttagataat aatggtctac cacaacttaa agtcatatga actccacaat
    27481 ttaaagtttt attttcttta agtaagccta ctccatgttc taccccaggc atatttgcca
    27541 tcatagaagt agacctaact ataccattat tatgagctga aattattcca tagttcacag
    27601 cttcacaata tccaaaatca tctgcattta ttataatttt agtcatacca taacctactt
    27661 tctatagaca actatctatt aaatctagga agataatctt tatgagcttc caacatttcg
    27721 tctaatatag tttttgctaa gtcatcagat ggaatcaatg ggtttataca aagtgccaaa
    27781 agagcagatt cataatcgcc atatacagct gctttagctg ccaatacttc aaatgatttg
    27841 atttgactta ctaatccatg cacagaatct ggtaaatatc ctatacttat tggttttggg
    27901 ccattttttg ttattacact acttacttct accgcttgtt catctttaaa atctcttata
    27961 gaacccttat ttaatgtatt aactacttgg atatcttttt tgtcattgta tatagaactt
    28021 attaaattac aagcagcatc actatagtaa gcccctcctc ttttttcaag ttgaggtggt
    28081 tttacatcta atttttcatc cttatataat tcaaataatt gttcttccaa ttctttaact
    28141 acttgacctc tagcttttcc ctctttaaac tctctcaact catcctcaag catttcttta
    28201 gttttatagt agtatctatg atatggacaa ggtattgcac ccaaagattt tacaaattca
    28261 gcattaaaat caattgcctt tatattttgc atacttatat ctgctttgac aaatttatca
    28321 attgcttctt ttgtaacatc ttctccatct aaagatacat ttagaccata aaccatatga
    28381 ttaagacctg caaaatccat acttattctg tcactttcta cattaaatag tttggcaaca
    28441 tcatttttta aatgaattgg cacgttgcat agacctatat atcttctaaa attagtatat
    28501 ttgaatacag cctctgttat tattcctgtt ggatttgtaa aattcaccat ccatgcattt
    28561 ggacataatt cttccacatc ttttattata tcaaatataa ctggtattgt gcgaagggct
    28621 ttaaataaac ctccagcacc attagtttcc tgccccataa ctccatgaga taaaggaata
    28681 gtttcatctt ttattctcgc atctaaaaga cctactctaa gttgtgttgt cacaaagtct
    28741 gcatctctta gagcttctct tctatctaaa gtaagattta ttttcatatc tactccagct
    28801 ttttttacca tcctcttagc tagatttcca actatctcta atttttcttt tccagcttct
    28861 atatctacaa gccataattc ctttacaggt aactcttcat atctatttat aaaaccctct
    28921 acaagctcag gagtataact tgaacctcct ccaattgtaa ctatttttag tccctttttc
    28981 atctcattat accatcctta cctataattt aatatactct acaaaaccct atacatttat
    29041 ttaccgaaat aaaactacct agttgttaat tttcaattta ttagcttcca ttttttcaga
    29101 cgctatgaca aatggaatat atattaatat tgataatatt aaattaaata gtgctaaagc
    29161 tccaccagtc cagtcacctg tagccattgc tccacctaat ataggaggtg ttacccaagg
    29221 tattttaggt aaaattactg gtgctactaa tccaaaatct attgctaagt atgatacagc
    29281 actacatatt actggtgcaa gtacaaatgg aatcataaat ataggattta aaactattgg
    29341 aagtccaaat atcaatggtt ctcctatgtt aaatattgca ggtggaccac ctaatactat
    29401 catctcttta cgtcttcttc cagctattaa taaagctact attaatccca ataccattcc
    29461 agaaccacct aaatatacaa atgcatcaaa gaatgcacct gcaagtacat ggtatccttc
    29521 cgttgctcct gcttgagcca aggcagcatt ttctccacct aatttcataa gtatagtttc
    29581 tgtaaaagga agtgctatat ttgcaccatg aagtccaaca gtccaaagta tatgaattat
    29641 aaatgcaata agcattgtag aacctaaact atcagctaca tttgatagtg gtgctcctaa
    29701 ataagtattt aaaatatctg ttaagaaact tccattggaa agcattttta taaatattcc
    29761 tattacagta aatatcatta tagttaacat tcctggtatt aactttgcaa atgatcttga
    29821 aactgctggt ggaactccat ctggcatttt tatagttaat ttctttacct tagataatct
    29881 tacaaatatc tcagttgata acaatcctat taatatagaa gagaataaag ctgctgtacc
    29941 taagtaggtt tgttgtatca ttccccatcc ttcaactact gtagttcctc cctcaggaac
    30001 tattttacca atttgtggag ccattataaa aaagatagat aaagctataa gcccagattg
    30061 taacccatca ctctcataag attttgctag aaaataagca acacctatta ctaagaatac
    30121 tgccattgta cctattgctc cccaccaaag gtcgcctcca aatgtggtcc agttttctcc
    30181 aaatatactt gccatcaaat ttttgtatgc ttccaatggt aagttattta tcaatgttcc
    30241 caatgcacct accatagtta taggtatcat tactataaat gcatctctta ctgctactaa
    30301 gtgcctttga gctcctattt tagcagctac aggcactata tatttatcca taaatgacat
    30361 gaatttttcc attttacatc ctccagtaca actttatttt gaactattta actctacagc
    30421 tctatctaac acagcttttc cattacatct tccataatcc atcatattta taacttctac
    30481 tggaatatta tatggttttg ccatttcagt tgcttttcct aatacatatc taacttgagg
    30541 ccctaaaagt aagacatcac aattttctat ttcatttttt aagttcactt ctgatatagc
    30601 ccatattttt gcttctatac cgttttcctt tgctgcatcc tccatttttg taactaataa
    30661 actagttgac attcctgctg aacaagctaa cattattttt atcatttttt cccctccaaa
    30721 ttagattcat taaatatttt ttaagtcata agttttttaa actatacatt taaaatatgt
    30781 ttttctatta attttttctt aatgtatata tcttattttt aaatgtatat acatttaatt
    30841 cttgatatta ttatatacca aatgtatata catttcaaga aaactttttc attttattta
    30901 aattttattc gacaacagca ttcaaagtta atgtatatcc atagtgatat gtgtgtgagt
    30961 actcaaaaat ctcactattt tgtaacttac aaatttggct tatatataaa agtggctctg
    31021 gttcttctaa ttttagatta tccatacatt cttcattcga tattacagct tgtacttctc
    31081 tctctgacat ggctatcttg tatccacaca cttcttcaac aaaattataa agagaatttt
    31141 cacaatgagt cttatttaaa tttggaaata acttaactgg catataagta atcatatatg
    31201 aaactcttgc atcattagct aatcttactc tttttatttc ccaaacattt tcttctaaac
    31261 ttatattcaa cttacttgat aaattttcat ctgcctgaac tatttcaaga gataccaata
    31321 tattagatac tttatagcct ttactttcca tctctttagt aaatccactt acagacgata
    31381 tattatcata tatattattt gcaataacta tactacctac acctctttgt ctagttatat
    31441 agccttcttt aactagatta ttaagtgcag accttacagt cattctagtt acattaaatt
    31501 cttcactcag ctgtttttca gaagggatta aatccccttc tttcaaactg tctgaattta
    31561 ttaactctct aacatgattt tctataactt tataaattgg ctctttcatt taattcactc
    31621 cttattaaat cttttatata ataagataat tttatataca aacaaagaaa atgtctatac
    31681 atttaagata atttaaattt tattcagaaa tcttgtacaa ctttccgagt tttaataaag
    31741 atataaatag acttatcatt aatatacctt ttaatatact tgataaggtt atactccacc
    31801 atacaccatt tagacccaac atttctggtc tagatataaa gtaagccaat ggtactcttg
    31861 caccagtcag tatagtaatt ataatagaag gtatataggt tctccctaat cctttgaaag
    31921 ctcctgttgt tattatttct aaacacataa aaaattgaga atagcctaat attttaagat
    31981 aaactgctcc tttttctatt gcctcacttt catctataaa aatagaaaat atactctctc
    32041 ctgcaaacac taatactaaa gtagttatta taccaagtac agaagataca gttatagcta
    32101 ttttgcaacc tttatttatt ctagaatact tcttggcacc ataattttgt ccaacaaaac
    32161 tgcctaatgc aactgatagc ccttcagccg tcatccagga aattgcttct atttgtgagc
    32221 ctactttttg tactgcaaca gccacaggcc cccatgatgc tactattact cctaatagca
    32281 ttgagaatac tgtaaacata ccactttgta ttgctatagg taatcccaat ttatacagaa
    32341 ctttataata tttagtctct atttctttaa atagtcttaa tttaaaatat tcttctttac
    32401 ttttaactat tatatatata aaacatgtag taactactat ctgagcaaat acagttgcaa
    32461 tagcagctcc tgcaacacca agttttggag caaatcccca tccaaaaatt aatatagggt
    32521 caagtataat attagttatt aatcctactg tattaatacg aaaaggagtt ttactatttc
    32581 caagaccatt gaaaattgca gtaaatactg gattaataaa ataaaatacc atacctagag
    32641 ctactattat caaatactgt ctagacatgg ttataacttc taagtctcct aatctaaaaa
    32701 aacctatcaa ttgtttatta agtactatta aagaaattgt atatattatt gctagtataa
    32761 tatttatttc tattgctgac ttcatatatg atttagtagt gcttatatta tttgcaccaa
    32821 tactttgtgc tacttttatc tctccaccta cttttgaaat cataataaat gccattgcaa
    32881 gccatggaaa aaaaccagct gttccaactg cagctactgc tttacttccg gctttaccaa
    32941 cccatatcat atctatcatg ttatacccca tctgtataaa tgaagtcccc attattggaa
    33001 gtgatagctt aagtaatttt tctgtaattc ttccttctgt taaattaagt ctgtctttca
    33061 ttttccacct cttttatatt aaatttattt gcttatatag ctagattaat cattttattt
    33121 gattgagttc actatccttc aatttatatt atcatatctc aggattgcat ctcaatcata
    33181 cttatgttta agatacagta ttttacctat ctatgataaa attaatactt atgaatataa
    33241 atctagccat ttcatcaata catattctaa cctttaactt aacttcaatt aagtatacat
    33301 atcgtaacca attagaatat tttatacggt atcttccatt aataaacaac caatatcaat
    33361 gatttatata taattttatt tatacataaa atagtatact ataataataa aaaaactata
    33421 tttgaatgct ttaagcatgt ttactaattg taatttccac acaaatttga taatatatga
    33481 atatattatg gtgaaattta tagatatata ttaattatgg ggagattgtg ggaggttctt
    33541 ttcacaagac atttaagcta tgaaaataaa taaaaaattc aatagagttg atatgcaggt
    33601 ttcaatactt actgcaatta ttgtaataat atcttcctca tgtgtatatt tttttaatta
    33661 tacactaact tataagagca tgatatactc tttaagtgag aggtcaaaac atatctatga
    33721 atatgtagaa agaaatattg ataaaaatac ctttactgaa attaattcta aagaagacca
    33781 atcaaaaaag tcttataaaa gttctaaaat ccttttagaa tctgtaaaaa atactactgg
    33841 agtcatgtat ctatatactg ctaaaaaaac aaaagatgga tcactagtat atgttgttga
    33901 tggtttaaat tcatctagga gtgattttag aaatgctggt gatttgatag aaaaagagat
    33961 ttggggagac cttaacaaag cattagataa tcatatattg ttacctaaaa agattaaatc
    34021 aacatcttgg ggatacatat ttatatcgta ttttcctatt cacaatgatg ttggtaaggt
    34081 tgttggagta ataggaattg aatttgaagc aaaacatcaa tacaatacat ttaaatttat
    34141 aagtatagtt acaccaataa tagcattatt aacttgtcta atatcagcat tgattgcagt
    34201 gattctattt aaaagaatat ctaatcctac atatactgat tttgctaata cagattattt
    34261 aacaggccta aaaaatagaa atgcttttga aatagatatg aataacttaa acaattcaaa
    34321 tctaaagaat ctaatatcta tcatatcaat agatttagac ggtttaaaaa agattaatga
    34381 taaatttggc catcagacag gagacttata tattaagcaa gcaagtaaaa ttatacaata
    34441 tgtaataaat aaaaaatata tagtttatcg tattggaggt gatgaataca taattattct
    34501 aaaaaattta tctcacaaag aaataaataa tattataaat aatattaatt taaaaatagt
    34561 tgaagaaaac tcaactaatg aattaaaatt atcaatgtct attggatatg ctatttttga
    34621 tgaaaaagta gatgtttctt tatttgatac atatcgtcgt gcagattctc aaatgtatga
    34681 taacaaaagg aaaattaata aacaatatca ataataaatt taaaaagtct attctttaaa
    34741 taataaatca caagaataga cttttttaaa tttgtgtttt tataagataa attatttaat
    34801 taaagtttgt tcttttttct aaacgattct ttataaattc atatattact ttcactaata
    34861 tatttgtgac taatattaac acagctagtg ctgctgcctg tgcagtactc cccttatcat
    34921 ctagttgtac aattgatatt gcagctactt ttgaacttgc agtatatata aaaactaatg
    34981 ctgatattgt caccatggag tttaggaaaa agtacataaa gttctctaaa actgctggca
    35041 aacaaagtgg tatagttacg ttcttaagaa ttgatgcgct gtttattccc attgatttag
    35101 ctaccatatc taattcttta tctactttct taatagcagt agtagctgtt ataaatgcta
    35161 ctgaaaagaa atgaactata ttacatataa ccattataag taatgttcca tataatccat
    35221 taaacaaatt cttaatgtat attgtatcca taaaattaaa ctctaattta ttaaaaaata
    35281 atacataagc tatacctaaa actaatcctg gcaatgccat aggcaatgta cttaaaaaat
    35341 acccaaatga ttttaaatat ggagcttttt ctgttttttc attcaaatat gcaaataaga
    35401 aaacaaagct cgtccctaga atagctgtaa atagtgacat ttttattgaa tttataaatg
    35461 gtttaatccc atcaatactg tttttcatag aaaaatgttc cagtgtcagt cttaaatcat
    35521 atggccaaac tgatattaat gaagataaga ttacagttaa cattacagct attataccaa
    35581 atgcaataat tcctacaacc cctcctaaaa tactatctct taacttatta gttttaacct
    35641 tatatggaat tgactttgaa gttatatatg aattttgatt tttttcaatt tttttagtta
    35701 ctataaacga tattattgca ggtattaaaa gtaatattga tacagttgct cccattggca
    35761 tattctgttg ccctataatt tgcttatata catctattga taatacatta aactctcctc
    35821 ctatcacctt tggagctcca aaatctgtaa aacataatgt aaacgatacg aatgcagaac
    35881 ttattaaaga gtattttata cttgggattg ttatgcttat aaattctctt atcttgctta
    35941 tccccatagt attactagct tcatatagtc tataatcggt tgaacttaga gatatataaa
    36001 gtatttgaaa tgattgagga aatacatata taatttgtgc caatattatt cccactgctc
    36061 catatattgg aacatgcact ccaagtaaat tagttaccaa accttgattt ccaaataaat
    36121 atactagacc tattgcatgc atcattgttg gagcaaacat aggaaacata gctaatgatt
    36181 taaaaaaacc tttaaattta atctttgttc tagttaatgc atatgcatat actaatgcaa
    36241 gtgttagtga tattacagtt gatataactg atacaaatac tgtatttttt agagaattta
    36301 atagagattc agaagccaag tattcttgaa agttttgtaa tcctacaaag actccatctt
    36361 tatctaaaaa agcctgtaca aatagatata ttataggtgc taataaaaat attactaaag
    36421 acataactaa tactgtaagc atacattttt ttatatctaa attcattttt gatttaagac
    36481 ttatactttt agaacttata gcattattat tcatacactt atgctccttt aacttttgga
    36541 tactttaaat agtatttttc gtctatactt atttttacaa ggtcaccttc tactaaattt
    36601 aaattaaccc actcttttat agaaacatca cttattatga aattttcatt taatttatct
    36661 tttatttcaa ctctcaataa attccctcta aactctatat tcgatattat cccttggtag
    36721 ttttcttttg tcgatttctc tatttgaaca tattctggtc ttacagttaa tatagaatct
    36781 ccattatcaa aacagtttgt atctcctata aattgagctg taaataggtt ttgaggattt
    36841 tggtatattt cttctggagt ccctatttgc attatatctc ctccatttag aatagctatt
    36901 ttatctgcca tagttatagc ttcttcttgg tcatgtgtta ccattattgt cgttatatta
    36961 agttcttttt gtaatctttt aatgtccatt ctaagcttgt gtctaacctt tgcatctaat
    37021 gcagacattg gttcatctaa aagtaaaaac tttggttcaa gagctaatgc tcttgctatt
    37081 gcaatcctct gttgttgtcc acctgataat gctttagggt atttatgagc ttcattagtc
    37141 aatccaactg tttcaagtac ttccttaact ttattatcta ttttttcttt tgaaactttt
    37201 ctctctttta gtggaaaagc tatattgtta taagcagtca tattcggaaa taatgcatat
    37261 gattgaaata ctataccaaa acctctcttt gatggctcta aatttgtaat atctttatcc
    37321 tggagaatta tagttccact atttacatct tcaagacctg ctattattct aagtaatgta
    37381 gttttaccac atccactagg tccgagtaaa catagaaatt ccccttcttc aatatccaaa
    37441 ctaatattat ttaaaacctt tttttggtca taacttttaa acacattatt tatttttaag
    37501 taactcatat cttatctctc cttatatagt tattttttta ttttaaattt tatatcctac
    37561 tttttcttct aaaattcttt catctaaatt attaatttaa actttactta ctttcagatt
    37621 ttgaaccgta ttttgattcc caagttttaa gtactgtact tctgtttttg gcagcagagt
    37681 ttaaatcaac ttcttttata agctgttcaa atggttgttt agaataacct tttggaactg
    37741 gattatctgt ctttatggaa gtaactgcta cttcatgtgc atatctatcc atagctgaat
    37801 cacttattgc ccaatctaaa aatagctttg cttctttttt tatattatct tttttaacta
    37861 aggcatttgc ttctaagtcc caacctgaac cttcctttgg aaatacaacc tctataggtt
    37921 ctccactaga taattgttgt gtagctctat atccaagtgt aatacctatt ggatactctc
    37981 cagagccagc taacttcgca ggttttgaac ccgagtgtgt atatgtggct atatttttat
    38041 gtaatttatc catgtaattg taagcatctt tttcacccat catttgaata agccctgata
    38101 ctgtaagata ccccgttcca gatgatgctg gatttggcat tgttataagt cctttatatt
    38161 ctggttttat taaatcttca taactttttg gaatatctat acctagtttc ttaagttcct
    38221 tataattaac tactattgct gtctctggga cactcattcc tacccaagat acatcatctt
    38281 cagtatcttt aaatttttta tcaactttat cataattttt aggcttatat gcttcaagtg
    38341 caccatcttt ttttagctct atcatgttca ttgctgataa tccccatata atatctgctt
    38401 gtggattatc tttttctgct aatagttttg aagctattac accatgagaa tccataacta
    38461 tctctacatc tatattggga tactcttctc taaaaccttc catataataa gctatctgct
    38521 cttcctctag tgctgcatat attgtaagtt tattatttcc ttttccttga gtagtttgtg
    38581 gtgttgttga tatgcaactt gtcataaatg taatcactac aatgcacaga caagtaaata
    38641 taaattcttt catatcttcc ccctttgtgt tttttccttt ttttatttgt tttttattgt
    38701 ttttgcttat gtttatataa tacacctaat ttgttaatat aaagttaagt gtaaattaac
    38761 agttcgttaa tttttagaaa tttttgttaa atatattatt tttagttaaa tacagtctgt
    38821 ttttaaacaa tatattaatt tttatagtat ctacatttta atttaaacat aaaaaataag
    38881 tctaacctct ataaagtaga atgttagact tatttttata agtatttaat tatacaacca
    38941 aatcattttt tttcttttct tcaagtgctt ttttaagcac catatcctta accttcataa
    39001 gtctagtagt acttgctctc tcattttctt caagcttcat agctatatac ttaatagtct
    39061 caatgtaatt tggtatcatt acattttcaa gagcattaac acgtctacgt gtcttttcta
    39121 tctcttgtgc aagaagctgt gcactttttt cactttctgc aagtcttaaa agtggttgca
    39181 tagcatctga gaaagcttcc atagcagaat ctaattcacc tgatgtaaaa gcaagaccat
    39241 aaggataaat atcactttga ttgttttcag ttttaaagtc aaacacagga acatcaacac
    39301 tcattatatt tctcgtagaa acatctactg aaactgattg ctttggcatc ataagtgctg
    39361 aacccagata ctcctgactc ataactgctc ttgcgattat aaagttttta taagcagtat
    39421 caagagcatt ttctgcttct tcacgcaatc gcttattttc tcttacaatc tcaagaaatt
    39481 gtttcataag ttcatcaagt ttatctttaa gaagcttatg acctcttgta gcagttttaa
    39541 ggagtttctt aagtctagtc atttccatac gtgttggatt tatatttaat ctagccacag
    39601 atatcactcc ttaggcatat atttttcaaa atattcatca cggatacgtt taagttcact
    39661 ttttggtaac atactaagaa gcttccatcc gatttctaat gtctgctcaa tagttctatc
    39721 agttctaaat ccttgtgaaa catattcttt ctcaaattca tctgcaaact tagcatacat
    39781 taaatcaatc tcagaaagtg cagattcacc aagtatagcc ataagttctt ttgcatcctt
    39841 acctcttgaa taagctgcaa aaagctggtt cattgtatct gcatggtctt cacgagtctt
    39901 acctttacca atacctttat cttttagacg agaaagtgat ggtaaaacat ctataggagg
    39961 ctgtatatct tttttataaa gttcacggct aagtataatt tgcccttctg taatgtatcc
    40021 tgtaaggtca ggaattggat gtgtcttatc atcctcaggc attgtaagta ttggaatcat
    40081 agttatagac ccttcatgcc ctttcatttt tcctgctctt tcatacatag tagcaaggtc
    40141 agtataaaga tatcctggat atccacgacg tcctggaact tcttttttag ctgctgaaac
    40201 ttcacgcaat gcctctgcat agtttgtaat atccgttatt ataacaagta catgcatatc
    40261 ttgctcgaaa gcaaggtatt ctgctgctgt aagtgccatt ctaggtgtag atacacgctc
    40321 tacagctggg tcatttgcaa ggtttacaaa cactacagaa cggtcgattg caccagttgc
    40381 tttaaaatcg cttataaaaa attcagcatc ttcaaaagtt ataccaactg cagcaaatac
    40441 aacggcgaac ttagaatcag ttccacgtac ttttgcctgt cttgcaatct gaactgcaag
    40501 attggcatgt ggcaaaccag accctgagaa tataggaagt ttttgccctc taaccaatgt
    40561 attaagtcca tctatagcag agactccagt ttgtataaac tcggccggat aatcacgtgc
    40621 tgctggattt attggagctc catttatatc aagtctttta tctggtataa tttctggacc
    40681 tccatcaata ggtctaccca ttccactaaa aacacgacct aatatatctg gtgaaactcc
    40741 aaagtcaaga ctctttccta aaaaacgaac tttactttca gcaaggttta tacctgttga
    40801 gctttcgaaa agctgaacaa gtgcagtatc tccatttacc tctagaactt tgcaacggcg
    40861 aatttctcca tttgaaagtt caatttctcc aagttcatca aattttacac cttctacgcc
    40921 gtttattaac ataagaggac cggctacctc ttgtattgac ttatattcct ttatcatagt
    40981 tcttcagccc ccctcttttt aataaggtct gcaagctcgt tgtctatttc atcttcaatt
    41041 gaatcgtaag ctgcatctat atcgccttct tctacatact tagcacgacc aatcttttca
    41101 agaactgaaa gcttgataat atcgtttata gtaacatttt gcttgatagc atcttgtgct
    41161 gacttataga attttaatat aagtcccatc attctatatt gtttatgaag tgatgtataa
    41221 gtatcaactt catggaaaga gttttgatga aggaagtctt ctcttataga acgagtaacc
    41281 tctagtatca atctatctcc atctgaaagt gaatcaacac caaccaattg aactatttct
    41341 tgaagttcag attcaacttg taaaagtttc atagcttgag ctctttgagc tgagaaatta
    41401 tcatttacat ttttatctgc ccatacatca actttttcct gatagagtga ataactagtc
    41461 aaccagttaa ttgctgggaa atgacgttta tatgctaaag atgcatcaag accccagaat
    41521 acttttacta tacgaagcgt tgcttggctg acaggttctg atgtatcacc accaggagga
    41581 gaaactgcac caattgctgt aagtgttcct tctctttcat ccatacctag acaatttacc
    41641 tttcctgctc tctcatagaa ttgagcaaga cgtgaaccta agtatgcagg ataaccttct
    41701 tcaccaggca tctcctctaa acgaccactc atctctctaa gagcctcagc ccatcttgat
    41761 gtagagtctg ccataagtgc aacactatat cccatatctc taaaatattc agctattgta
    41821 ataccagtgt atatagaagc ttcacgtgca gcaaccggca tatctgatgt gtttgctata
    41881 agcacagttc tttgcataag tgactcgcct gttcttgggt cttttaattc aggaaattca
    41941 agaagaacat ctgtcatttc atttccacgc tcgccacagc ctatatatac aactatatct
    42001 gcatctgccc atttagcaag ctgatgctgt gtaacagttt ttccacttcc aaaaggtccc
    42061 ggtatagctg ctaccccacc ttttgtgatt gggaaaaatg tatctataac tctttgacct
    42121 gtaacaagaa gtgaatctgg tgttttcttt tctctatatg gtctttcttt tctaactggc
    42181 catttttgca tcatagttac aggtatatca ttaccttttt catctgtaat aacacaaact
    42241 gtatcttcaa cagtaaattc accagaatat atttctttta tagtaccctt aactccataa
    42301 ggaaccataa ttttacattc tactactgct gtttcttgaa cgccaccaat tatatctcct
    42361 gctacaacct tatcaccaac agatttttta ggtttaaatt cccacttagt tgttctatca
    42421 agtgaagata cttcaacacc tttagttata ttagtacctg aaatatcata cattttttca
    42481 agtggacgtt gaataccatc ataaatagtt gaaataagac ctggtccaag ttcaacactc
    42541 ataggcattc caagagaaac tacttcttcc cctggtccta gaccggaagt ttcctcataa
    42601 acctgtatag aagctttatc tccatgcatt tctataatct cgcctataag atgtttatct
    42661 gaaactctta cgacgtcaaa catattcgca tctctcatgc cctccgctac aacaagcggt
    42721 cctgacacct ttacaattgt gcctgttttc atattctctc acctgcaatc atatacttta
    42781 tcaaaattta aatattccct cctatatttt attagtacat atatttagca ccaataaaat
    42841 ttgagattgt cttttattca actttcatct attctttaaa taatatatct gcacctatag
    42901 cacgtttact agattctctt acttcattca tacctaatcc catacttcct ccaatacctg
    42961 gaataactat aatggcagga agttggtaat ctttgtattt tgctattgat tcttttgcaa
    43021 gcaatgatgc ctgttctgta atataaatta tcgcatattc atcttcaacc aacttatgta
    43081 tacttttttt aatttcgtca ctatcatagg ctgggaagat atctattcca agagctaaaa
    43141 atcccatgat gctatcttta tctccaacta ctcctacctt atacataagc atcccttagc
    43201 ctttctttta tagtatctgc gtctatatta ttaagcttac tagtcaaaat aattctaatt
    43261 gtttttatct ctgattcttt agcatataaa tatgcaatta gtggttctaa tgtaagaggc
    43321 ttaaattttg ctcctctaac atattccata agatagtcat cacaaagttt ttcaaagaca
    43381 gtaaaaccac tatccatgcc atttttacag acatcagagt aagaagtaga tttaaaacat
    43441 gatgctggag tatctgagga aaaagcttct aagaattttt ccttatcaag tgagccacct
    43501 gaaacaaaca cattcataaa catatcaaaa tctttcttca tatttttgac tcttataaaa
    43561 ctctttagat ttgttaaatc acaaactttc ataacataat ctattacaaa tttgttttgg
    43621 ctttctttag cagtttcttt catactggta aaggttgctt tatctagaac aatatcaacc
    43681 atctggccat tttgtgtctt attataaaca tcaaatgcct ctaatatagc tgatgacatt
    43741 atcttaggta aatcactaaa actacgattt gctaaagatt ctctaagctt aataagagga
    43801 attgtacctc catcaattaa atatttctca ccatctacac cagaaatttc ttctttaatc
    43861 agcactttta aattgtgata gtcattttta taaagaaata catcaacaaa tttttcttca
    43921 ggagctagac ttttaagaat ttcatatgtc tttgataatt cttgagtcaa aatattctca
    43981 aaattatgta tattattatt tgatgtatca gcataacctg cctcagctat aattcttaaa
    44041 gagtcttcag ggcttttggc ttctgccatt tgaataaaca tttgtctgtt aagaagctgt
    44101 ttttcaagca ctcttattcg tgcaacggca tagggataag ttttttcttc tgccattttt
    44161 taacccctcc ttaattaaac aaaatttctg ctgcaatttg ttcaatatat tcatgctcta
    44221 ctgcaattat ggcttcaaat gaataattgt actcaatgtc acctttttta actatgaaac
    44281 ctccagtaat atctctagtt tcatcagaca ctttaatgcc tttttttgat agcacatctt
    44341 ttaatgtttt tttatctttt ttagataata ctatctctga atcatctgta caatttgatt
    44401 tttcaatcat gtttagtata atctcttcat attcattatc tttaagattt aaaagtttgt
    44461 ttttagcttc taaaattacc tcttctaaaa tctcttgttt ttttgataat atttgctttt
    44521 tagcctccat ataagctcct gatatttcct tagaagccgc tttttctgct tctgcctctg
    44581 caagctttgt ataggaagcc atttcctttt cagctttttc attagctgaa tttactttta
    44641 aatctgcttc acttttagct ttatccaata tttcttgtgc ttcttgtttg gcatcagcta
    44701 taattctgtc aatcattttt tgttcattac ccataggagt gcttcctcct tttcattttt
    44761 tttacttatg aattataatt tataattaac caattgcaat tccattgtaa gctaagaaag
    44821 aaacaagtag tcctaaaaga gcatatgttt caactattgc tgcaaatgtt atagctttac
    44881 caagttcttc aggtcttttt gcaactattc caactcctgc tgctgctgct ttaccttgtg
    44941 ctatacctga tactaaacca actaaaccaa ttggaagtcc tgccataaga agttgtaaac
    45001 cttgagctga tgttggtatt gcatctccac caataatccc tgcttttgat aaaataagga
    45061 aagctatgat aaatccatac agaccttgtg taccaggaag aagttgtaaa actagaagtt
    45121 gaccgaattt actagggtct tctgttacaa cacctgctgc ggcttgacct gctattgaag
    45181 tacctttagc agaacccata cctgcaaata atgctgctat agcagctcct gatattgcca
    45241 aaaattgacc atttcctaac gcgtttaaaa attccatatt tacatctcct ttttattaat
    45301 gcttgtatat tttgttttat acttaaacgg aacaaaagga actcctccgc cttcataaaa
    45361 cttattgaaa aattctacat actgtaacct acttgtatga acatatgcac ctagtgcatt
    45421 tataagaagg tttattgtgt gtcctacaac accaattaca actgcaagta tcggaccagc
    45481 tatagcccct aaaaggttga taacttgtgc tataactcct gttgttaaac aaagcgccat
    45541 aattcttgta taagataata tatcagcaaa ataacttgtt ataccataga gacttgaaaa
    45601 tcctttaaaa agcttaacag gaataccttt aaagcttctt ccttgagtaa gtacaagacc
    45661 tatagcacct ataattgcta aatattttcc tacttctgaa aatacaccta tgtcccctgc
    45721 aacaaaaggt attataagta gacatacacc tgttatacac aaataccaaa aacctatgtc
    45781 aaagattgca tctattacct ttccacttct tattaatgta tatgctttta ttcccaaacc
    45841 tacatatata tggataatac cgaacagtaa cgacattccc ataagtgtca taacatcctc
    45901 taaaggatta attaatgctt ttataggaat taaatccccc aaaatacccc cgaatataag
    45961 accccataca gtagttgaaa ctccacagat accaataagt ttaattaaat ttccttcacc
    46021 tttttgtatc tttaatttat atacaacaaa tccacaaact actgcaatta ttaacccata
    46081 tgcggcgtca cttagcatca ttccaaagaa tataacaaag aagaaagtta aaattgtatt
    46141 tgggtcaata tcttttgtac ttggatagct gtacatgtta gttacacttt caaaaggtgt
    46201 tactaattta ttgttttcaa gcagaattgg gaagccttct tctttacttc cttcttcagt
    46261 ctgaacacaa caatcaaact tttctgtaat ttctttaatt aattcatctg cccttttgct
    46321 tggtaaccaa ccattaagac agaatgttgt ttttgttttg acaagtctct ctataatctt
    46381 tttttggtct ctttctatag tgtaaaaatc atataggttt tcaagcatgt gtatactatc
    46441 tgcatgtctt ttaatttcct ctgttttgtt cttagaaacg ttttcctgtc taattatcat
    46501 ttcattgtat ttcttgatag cttgtaacgg tgtaccttct tcatttggta atgaaaccac
    46561 tgaaaaatta aattctttta aaacttctaa aacatcatca aaagtttctt ttaaagtaat
    46621 taaataaaca tagttcatta acttgtcaga attgacaatc ccaataacac tttctggtat
    46681 ttcatcttct aattttactc ttaaagcatc aatgtttgcg cttatgggca cagttccaag
    46741 tatagttttt gtatacttag tttccatatt ttcaatagga atatcaaagt tcacccatgg
    46801 ttctaacata cttttattgt tgttaagtaa gtttatgtta gaccttattg tacctatctc
    46861 cttgtgcaaa ttgtttaact ccagagcttc agcataaact tgcccttctt tttcactatc
    46921 aattttgtta aactctcttt ttggtgcaag tagggatttt ttttgtttca ctagtgaaga
    46981 aacaatatta attgcttggt ttacatgaga cattttctgc tctagcatta taacttcaga
    47041 ttcttcacta tcttttacaa gataattttt taattcctcc tcctcagtaa gaaaggcact
    47101 atcatcaatc tgaacaaacc cacggttcat aagtagcttt aaaatctggc ttttttgagc
    47161 ttctaagcca acaatagata ttttgttcat attaactatt gccatattat ctcactacct
    47221 ttccaataac cgcttcaata gccttacttt ttctttcttc agcagttttt tcaattttca
    47281 gacattcact tttagcatta gctaagattt tatcaacctc tgctctactg tcggtgactg
    47341 ccttctcaat aagagtttct tccataagct ttgcttgttt ttttacatca gcaaatatgc
    47401 tttcacattt gtttacagca tcagctctga tagactctgc atcagtaaca gcttttactt
    47461 tgatactgtc tgctgtctgc tctgcctcaa caatgctttt tattatttca aaagccatcc
    47521 aaatcacctc tcttaccttt ttactatgta tataaccaat tagatttttt tattctaatt
    47581 agattactac ctcattgtta aagtataaac agcattttta tataataatt aatatttttc
    47641 aacgtttatt tcttaataaa acatatttta gaatagtact tgcctagatt tacatccttt
    47701 tttgacttac ttttagacta tgacatgagt atggttttta aataccatta ttttcaataa
    47761 ttataattta aagcgatata gtttgtcaat agcgttattt tgttttaaaa ttaacgttat
    47821 gtcgacatt
//
LOCUS       DAEQAF010000018        45867 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.019, whole genome shotgun sequence.
ACCESSION   DAEQAF010000018 DAEQAF010000000
VERSION     DAEQAF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45867
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.019"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            63..701
                     /locus_tag="KRN00_001154"
     CDS             63..701
                     /locus_tag="KRN00_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827021.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQSYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(1194..2954)
                     /locus_tag="KRN00_001155"
     CDS             complement(1194..2954)
                     /locus_tag="KRN00_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1827022.1"
                     /translation="MQEVEVIKAKNVLARQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSKYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKTQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(3017..3160)
                     /locus_tag="KRN00_001156"
     CDS             complement(3017..3160)
                     /locus_tag="KRN00_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1827023.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQSLMKDYNVLSD
                     ITA"
     gene            complement(3479..3718)
                     /locus_tag="KRN00_001157"
     CDS             complement(3479..3718)
                     /locus_tag="KRN00_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1827024.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            complement(3723..4139)
                     /locus_tag="KRN00_001158"
     CDS             complement(3723..4139)
                     /locus_tag="KRN00_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1827025.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGAMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            complement(4136..4435)
                     /locus_tag="KRN00_001159"
     CDS             complement(4136..4435)
                     /locus_tag="KRN00_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1827026.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFAVGYQIPPFMVSVSAKRGRSLFALATFAGKGVRL"
     gene            complement(5486..5653)
                     /locus_tag="KRN00_001160"
     CDS             complement(5486..5653)
                     /locus_tag="KRN00_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827027.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            complement(5666..8431)
                     /gene="mgtA"
                     /locus_tag="KRN00_001161"
     CDS             complement(5666..8431)
                     /gene="mgtA"
                     /locus_tag="KRN00_001161"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH1827028.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            complement(8597..8908)
                     /locus_tag="KRN00_001162"
     CDS             complement(8597..8908)
                     /locus_tag="KRN00_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH1827029.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            complement(9155..9832)
                     /locus_tag="KRN00_001163"
     CDS             complement(9155..9832)
                     /locus_tag="KRN00_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1827030.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            complement(9970..10473)
                     /locus_tag="KRN00_001164"
     CDS             complement(9970..10473)
                     /locus_tag="KRN00_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1827031.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            complement(10489..13152)
                     /gene="mgtA"
                     /locus_tag="KRN00_001165"
     CDS             complement(10489..13152)
                     /gene="mgtA"
                     /locus_tag="KRN00_001165"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBH1827032.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARQSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGIYTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            complement(13245..13454)
                     /locus_tag="KRN00_001166"
     CDS             complement(13245..13454)
                     /locus_tag="KRN00_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827033.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSRPNETDLIELKNAISK"
     gene            13404..13739
                     /locus_tag="KRN00_001167"
     CDS             13404..13739
                     /locus_tag="KRN00_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827034.1"
                     /translation="MTHMSADKLLLGFHLDHVSNLNELLRKVAHNNICIMSDRMTKVA
                     VWKPSVKTIQLVCMEYLNYIIDHSVIYEKIQCANWNGTEETNSIFNNSPSPLITLIYS
                     CDLQQNKTT"
     gene            complement(13938..14840)
                     /locus_tag="KRN00_001168"
     CDS             complement(13938..14840)
                     /locus_tag="KRN00_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1827035.1"
                     /translation="MFKKNKKQTENVKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIDARTQAISG
                     YLTKELQDLNMDTIRTDIPTSSAITDVIVWSIEQSGTDTFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDAGGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKESNWKIIG"
     gene            complement(14857..15864)
                     /locus_tag="KRN00_001169"
     CDS             complement(14857..15864)
                     /locus_tag="KRN00_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBH1827036.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFFGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPSS
                     LDTESSIKQGCKYFASLLSSCKNQDIDDLNVAIQSYNYGGGYVGYVAGNGKKHTFNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVFGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYTDLSSSYWQQHLIGAGRVK
                     Q"
     gene            complement(15861..18065)
                     /locus_tag="KRN00_001170"
     CDS             complement(15861..18065)
                     /locus_tag="KRN00_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1827037.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIITVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRSERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARQAQRKADGSATTGATRPHER
                     PATASTVSKTGAEKMQEVKRPATTPTTKASEPVKTSGVKERPLSSSTPDGKATQSTYR
                     QNVEKVTVSKETRQNYTKDRRTKVQQTQTVQKNQQTTEKIRNLVTKKGQKKK"
     gene            complement(18065..20515)
                     /locus_tag="KRN00_001171"
     CDS             complement(18065..20515)
                     /locus_tag="KRN00_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1827038.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(20493..20891)
                     /locus_tag="KRN00_001172"
     CDS             complement(20493..20891)
                     /locus_tag="KRN00_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1827039.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(21009..21512)
                     /locus_tag="KRN00_001173"
     CDS             complement(21009..21512)
                     /locus_tag="KRN00_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1827040.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            complement(21530..22033)
                     /locus_tag="KRN00_001174"
     CDS             complement(21530..22033)
                     /locus_tag="KRN00_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBH1827041.1"
                     /translation="MQETRVLVETRGTTGEETISYWFDLPIDVAEFEEKLGVGAESGD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVYENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(21952..22248)
                     /locus_tag="KRN00_001175"
     CDS             complement(21952..22248)
                     /locus_tag="KRN00_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBH1827042.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     EDFSKYVFGMSYQTIKDVRKQQKGREEQCRKQGCWWKREEQLAKKQYHTGLTCR"
     gene            complement(22331..22972)
                     /locus_tag="KRN00_001176"
     CDS             complement(22331..22972)
                     /locus_tag="KRN00_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HBH1827043.1"
                     /translation="MEYKYTKIDLEKWNRGKLFQSYIDDMRIVMSLTVDIDVTNLIEF
                     SKSHDLKFYPAMIWVVSKVVNEHDEFKYSWDNKGNLIKWDYISPSYAEFHKEDENFTK
                     MVTDFSDSIFEFHERFMLDREKHKMERAFVANQPLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELERERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSIS"
     gene            complement(23180..23401)
                     /locus_tag="KRN00_001177"
     CDS             complement(23180..23401)
                     /locus_tag="KRN00_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827044.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(23402..23536)
                     /locus_tag="KRN00_001178"
     CDS             complement(23402..23536)
                     /locus_tag="KRN00_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBH1827045.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSIGKEADYEMKQLEESEDN
                     "
     gene            complement(23549..24745)
                     /locus_tag="KRN00_001179"
     CDS             complement(23549..24745)
                     /locus_tag="KRN00_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBH1827046.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVTSGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLNEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQATLSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(24929..26323)
                     /locus_tag="KRN00_001180"
     CDS             complement(24929..26323)
                     /locus_tag="KRN00_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1827047.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLEKGLTLSPYNLITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNSFYEGMVQRSEEMKQHSNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLKTIGSLAQARQ
                     DGTATCEAKGDGTD"
     gene            complement(26390..27004)
                     /locus_tag="KRN00_001181"
     CDS             complement(26390..27004)
                     /locus_tag="KRN00_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827048.1"
                     /translation="MSEKLLDLLKIFLEKYLVPTVIAIVFSFIAYYVTPTDNKLLVKF
                     TIWGYAVFLFCVWFLIIELVIWLVQKIQYHNYSKGVEQRNKQRQAEEWQQSLEFLWTD
                     VDNLSSSDYKLLLRFIKNENQPYCSSGTPMGHCLLNSDWVHKTVSKPAKRVLIKSNQR
                     TSSKAIPIPVYETISETYQYILREDIYQMLKYSYEKYGKISHFK"
     gene            complement(27095..27478)
                     /locus_tag="KRN00_001182"
     CDS             complement(27095..27478)
                     /locus_tag="KRN00_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1827049.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGNPQNHTPQGQTKK"
     gene            complement(27494..27820)
                     /locus_tag="KRN00_001183"
     CDS             complement(27494..27820)
                     /locus_tag="KRN00_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBH1827050.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPIFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            complement(28059..31112)
                     /locus_tag="KRN00_001184"
     CDS             complement(28059..31112)
                     /locus_tag="KRN00_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1827051.1"
                     /translation="MKKMLKRLCTGFLALATIVTALPTTPVHAESKQYWTESAERVGI
                     IEKVMNDGSIGSTFNEGMMKVEGETAYCIDINTDFKNGYKTRTDASSRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFSGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNTKLQKVSSNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDENGNTDIVEVKAGTVYIKELSAPAGYKVDKT
                     VYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQAGDKSEQIKGLYVTQITEDGDLAVLSGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNAVLVEGKLYKKNEVVKTIH
                     TDIEGVASTSADLLPYGNFRIVESEAPNGYLTDGAKPIDFAITENEKIMDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHIVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKNGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELVIDGKRVENDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKIAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDITIIDTVT
                     LEGLEVGTQYKLVGWQMLKEKNAELLINGKRVESDYTFTADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDEPKKVTEHKDIEDEGQTITFKEKPEVPEEPEKPETPQTPE
                     EPSRPSDSPKTGDSTNVIAFLVMLLTSGGGLAGTYLYKRRKMKKS"
     gene            complement(31357..32721)
                     /gene="rlmD"
                     /locus_tag="KRN00_001185"
     CDS             complement(31357..32721)
                     /gene="rlmD"
                     /locus_tag="KRN00_001185"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBH1827052.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIHDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSDNLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIVGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCIEAQPVDMFPHSTHVETCVLLQ
                     RRTM"
     gene            complement(32896..34656)
                     /gene="pyk"
                     /locus_tag="KRN00_001186"
     CDS             complement(32896..34656)
                     /gene="pyk"
                     /locus_tag="KRN00_001186"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBH1827053.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(34708..35667)
                     /gene="pfkA"
                     /locus_tag="KRN00_001187"
     CDS             complement(34708..35667)
                     /gene="pfkA"
                     /locus_tag="KRN00_001187"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBH1827054.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(35876..39445)
                     /locus_tag="KRN00_001188"
     CDS             complement(35876..39445)
                     /locus_tag="KRN00_001188"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBH1827055.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMSSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIEYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKALEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(39602..40549)
                     /gene="whiA"
                     /locus_tag="KRN00_001189"
     CDS             complement(39602..40549)
                     /gene="whiA"
                     /locus_tag="KRN00_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBH1827056.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(40566..40991)
                     /locus_tag="KRN00_001190"
     CDS             complement(40566..40991)
                     /locus_tag="KRN00_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1827057.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(41060..42166)
                     /locus_tag="KRN00_001191"
     CDS             complement(41060..42166)
                     /locus_tag="KRN00_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBH1827058.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLENGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVKHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(42178..43035)
                     /gene="rapZ"
                     /locus_tag="KRN00_001192"
     CDS             complement(42178..43035)
                     /gene="rapZ"
                     /locus_tag="KRN00_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBH1827059.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(43066..43779)
                     /locus_tag="KRN00_001193"
     CDS             complement(43066..43779)
                     /locus_tag="KRN00_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH1827060.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(43783..44697)
                     /gene="murB"
                     /locus_tag="KRN00_001194"
     CDS             complement(43783..44697)
                     /gene="murB"
                     /locus_tag="KRN00_001194"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBH1827061.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKKESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(44970..45740)
                     /locus_tag="KRN00_001195"
     CDS             complement(44970..45740)
                     /locus_tag="KRN00_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH1827062.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
BASE COUNT        13345 a         9911 c         7043 g        15568 t
ORIGIN      
        1 atgtatataa gagtattcaa tgtactagaa aaaatcaaaa gaaatattag aagaaatgga
       61 tattgagtaa tcaaagaaaa gattttgata ttacaaatga tatgtttcaa gaaagcattc
      121 ctatcacaac aaaaattatt cttgaagaca tgccttcaaa tgatgaatta aatcatgttt
      181 tttcaaaagg ttgtgaacga aaaatgaaaa agagaaaaat tgtattaatc acactactat
      241 taataggtgt tttgttatta ggaagtatcc tatataatct ttttttagga aaaacagcta
      301 atatttcaat gctaaaggaa tcttggaatt ttgatatacc aatacctaac aaagaaattg
      361 aagtatttga tactcaagat agtattaatg gagatggaca aagttatttt attcaaggat
      421 tttctgaaaa aaatttcaaa aaagttttta atttaaaagg tggtatagtt gtaagcaaag
      481 ataatattaa tgaaatagaa aaatatattg ataaatttaa aagagattct gttaacatta
      541 ataaaagtaa taaaaataaa attgaagaag attttaaaaa atataagtta gaagttaaaa
      601 aagatgataa gtatatatat aagagaaatt atgagaacta cgtagtttta attataaaaa
      661 aagatgaaca aaaattatac agtttaatat ggaatcagta ggtacatatg tattattaag
      721 aattataaat aataaaaata aattttagtc aatatacaaa aaccttttaa attgtctgga
      781 aatcacctct tcatttgtta taaaaacata caacaaatga agaggtgatt ttatggtttt
      841 aaaaaaataa ttataagtgg atatgtgctt taacatgttt attaacattt gtaacgccta
      901 tatttgttaa tgaattataa tataaaaata ttaaataata ttcaactata gattatgtaa
      961 attactctat gaaaaaaata agttgtataa aatctggcta ctgtagattg actatttctt
     1021 ttaaaattac aattataata agttttatag aattaaaaat aaaactttag agatttttga
     1081 taacattgta gactaaattt gccaccaaaa tcgctttaca gtggcaaatc ggtggcaaat
     1141 acaatatatt attagtatat aatctatata aacattacta ttgtttgatt atcttagcta
     1201 cagtttccac atgtgtcgtt actactatcg gaacacattt tatcaacctc gttgctgtca
     1261 tgtgaacaca attcattagt cctatgccgt cctcttgcat ttttcctttg tgttttaaat
     1321 ttagcaccat ctacgctatt cttcaagcct gttttataaa caaaggtcaa ctgtgcaggg
     1381 tcaacatttc cgttttcatc aagtccacct acaattactt tttcaacaat gctttcaaac
     1441 acatagcggt caaatttatc aagaacctca ttctgttcca gagttttctt aaactctttc
     1501 aaacgttttt ttatgtcttt ctcattatca gaagtttctt gtaacttttg tctttcttca
     1561 acaagctgtt cttgtttact tactaaatca gcatatttac tttcgtaggt ttccttatca
     1621 ataatttctt ccagacgcat atccacaagt ttactttttt tcttctctaa tgcgtctatc
     1681 tccttttccg cttttgcaag ttgttttgac accacactac tactaagagt atcgtccatt
     1741 ctctgcaaaa attcttccag aacatcttta ttatcatcac ataataaacg ataactttct
     1801 acaaatgctt cttcaatagc tgtttctgga atacctttgc tatgtttaca aaatttcttt
     1861 cctttcttcg tagccgttac acattgccat ataaccttgc tgtattttga gccactgtgc
     1921 caattacgtc ttgttaaagt accaccacaa aagccacatt ctagcataca gctaaatgcg
     1981 tatttcctgc tatacttctc acgcttaccg ctgcctaccg ttgttcggtt cttatttctc
     2041 cgattaagaa tttcctgtgc tttttcaaaa acttcttcac taataatcgg ctcatggtga
     2101 tctttcatat aaaatttatc ttcttcaccc atgttttcaa ggcgacgttt ggaaatcgga
     2161 tcaacagtaa aagttttgcc taagagtata tcacccttgt atttctcatt cttaataatt
     2221 ccaataaccg tagatggtgc ccatgtggaa ctcccatact tcgttttata acctagactt
     2281 tcaagctcct gtccaataac agaaccacca gcaccatcaa cataacggtt gaaaatatat
     2341 ctgacaatct ctgcttcttc ttgatttaca gttattgtct tatcctctgg gtgataatca
     2401 tatccaatac aaccttgaaa acctaccagc tcgccgcgct tcattttcat tttcaaccct
     2461 ttttttacat tggctgaaat gttctcgact tcctgctgtg caacagaact aagaacaaca
     2521 agcaataact ctccatccat tgtaagtgta ttgatttttt catcttcaaa ataaacggcg
     2581 atatttctct cttttagcat acgaacatat ttcaatgtgt ctaaagtatt tctggcaaat
     2641 cttgatatgg attttgtaaa taccatgtca atttcaccat tcatacagtc atttatcata
     2701 cgctgaaaat cttctcgttt tgttacttgt gtccccgtaa ttgcttcatc agcataaatg
     2761 tcagctaaca cccattcctt gtttttctta atcatgtcag tataatactg aacttgtgat
     2821 ttataactgt ttaactgatc ttcgctatct gtacttacac ggcaatatgc agctacacgc
     2881 aaacgctcaa tggcttttcc acgggcttgt cttgccaaaa cattttttgc ttttattact
     2941 tcaacttcct gcatagtaca cctccttatt ttgtgttcct ttcatattgt tattgtacta
     3001 ctttaaaaaa cacaattcaa gcagttatgt cagaaagcac attatagtct ttcatcagac
     3061 tttgttttac aagagtgtat tctttttcag aaatcagttt acgggcaagc agttgtttta
     3121 acatagcaat ttgcatacta tacctaatta tattattcat taaaaccctc cttgcttttt
     3181 tatttatgga agtaatcaga cggcttcggc agctccactg gactttcacc attcccattc
     3241 tgatgggtga accgtgtcat acgggtgtat cattattcag atatacgagt catggcagca
     3301 acctttccaa agatcgcttg cggttcactg gcataatcgc tcgctgcttt ccccatttca
     3361 gtggtcgtgg cgttccagtc cgctggctcg tcgtatatca aacgtatctg attactgtat
     3421 tcacttgtca aagaacggaa aagagttaaa atgaggtggt agatactctc tgttatattt
     3481 acttcacttt gacttcaaac cctaagatta ctttaatcaa cgctgcccgt atcctgcctt
     3541 tcagttccat atcaagcacg atatacatat tcccgtgttc gtcatagaac gggcgtaggc
     3601 tggcttttga tatgtaagcg tcataatggt tcaaaatctt ttcaattgcc acctcgttac
     3661 cgtcagctgc agaactgatg gtcgagaatg atggacactt ttttgtagac ttcatcatgt
     3721 ttttattcct cctcgtacat atccttaata agctttaatg tgtgcagcct gtttctacat
     3781 acggaaaatc gttccatttc cataacctct gcaatttcag cgtcggtcat ttcaagaaag
     3841 taggacataa gcagaatgtt acgtcggctt tctgttaatt ctttgatagc ttcacataag
     3901 cgttcatcat agatatggac ttctgaacca aatacatcaa atgacgtaaa ctcaacgcaa
     3961 tattcgtcca tggcaccgat ctggtttaac tccatttcag ataaatcaca gaacggcgtt
     4021 tcacgtcttg cacgtctgcc aagctctcgg tcatagttct ttacagttcg tcctacaacc
     4081 ttgcgagcta gacaatcaaa ttgaagtctg atagcgccct cgaaagaaga tggtttcata
     4141 atctcacccc ctttccagcg aaagttgcta aagcgaaaag acttctacct cttttcgcac
     4201 taacactcac catgaaaggt gggatttgat acccaaccgc aaaaattttt tgaaaaagtt
     4261 ttatgcagta aaaaagcaca agggcaatac agacgtactg atcttgtgct aaacaaatta
     4321 ttcctgttat atgctgtaaa aaaccacata taggagcatt atgttccgta gaatttaaat
     4381 gtttttttaa tgaactaccg atggtcgaaa gttgttgaat atgtaagtgt ttcatacggc
     4441 tacccctaga gccgataaaa caagaccatc cagtaatttg tccaacgtta ggcaaaaata
     4501 aaacggcggc tatataaccg tcgtcttatt caaaagttca aaaagaacta aactaaaccc
     4561 tctaaagcag tatgtattta taatcagtct tgcaaaataa caaagtagaa ttgaaatata
     4621 aggtagcaat ccttgtgcat ctaataaact tataggggtt acagcagacc acggaataat
     4681 attttgtata ctttcagatc aatatagtcc aacaaaacca attcccgata tttagtaact
     4741 aaaaagtaaa ctagagtaga aaacatttct ttgcaaaaca caaataataa gtaatggact
     4801 cattgacaat agattgagaa atccagtttt ttagacttag atagattatc tcacttgtaa
     4861 atgatttaag ttctttgact tcatatatag cggtataatc tgtcaacgtg atcattacaa
     4921 accataatgc ctatataaca tactttccaa gcaaaaactt tattctatta gttggggaat
     4981 acaaaatatt tatcattgtg cgttcaacat attctttttg tataaaaatg taattacaaa
     5041 acaccactca atataagata gataataatt tgaataggaa ttatcaatct acgtaaccat
     5101 tcattacctg tcattgttgt tacaatagat ttgggattct gtttccatta cataattttt
     5161 ttatccttct ttcagatatc tcctcatttt atcgaagctt cttctacaga catacattcc
     5221 ataataaaat ctacctttga atattatttc acgatttcgt tatagacgcg taaacaaaca
     5281 ataaaaaacg aaatttcttt taagtaccat aatttttata tcgaaattac aattatccac
     5341 ttatatacag catttatagg taattcaatg ataaaaaaac acatacttta ctactaaatt
     5401 gccacaattg aatgcgcctt gatatgatag ggagattcca caataaaaaa ctgtgcatct
     5461 cccttgattc attcatactg atatcttatt tataagactc ttttgtgtct ttttttggtt
     5521 tcatggacca aaatactaca ttcattacaa taacaatcag caacacaact gccatagcca
     5581 cccaaaagcc gatattaaga ccaagccatt cggtagttcc aaaaagggtc atccaaagtt
     5641 ctttccagtt catcattcca cctccttaaa gcagttctcc gaaatgacgg acataggctt
     5701 tttttaaact tgttgccaaa gtcatataca gcagaataca tggaatcaga taagcaaagt
     5761 atgctgcagg caatgcaaca aatccaagca tagttccaaa cacagtaaac ggaataatgg
     5821 tcagaactat aattccagtc attgttagca aagtcaccgg agctgatgca cgactctgaa
     5881 caaaaggtag ctttggagta cgaatcatgt gaatgactaa tgtctggctc cacatagatt
     5941 ccacgaacca ccctgcttgg aacatcccga tatactgtgc ctgaagcatt gccagttctg
     6001 caccgctgaa atgagcaggc aaatcattaa ataatacacc attcgatacg aacaatggac
     6061 aaaatacaaa gtacataaaa atataggttg taaaatcaaa gatagaactg gttggtccaa
     6121 tccagatcat aaaacttcca acactggaag cgtcccattt acgaggtttg gtaataaact
     6181 cctcatccac attatcccaa ggaattgcag tacaggataa atcataaatt aagtttagaa
     6241 atataagatg aacactcatc attggtaaga aaggtagcaa agcagatgca gcaagcactg
     6301 agaacatatt gccgaagttg gatgaagcag tcattttaat gtacttgatc atgttggcat
     6361 atgtctttcg tccctcaata ataccctgtt ccaaaaccat cagatctttt tccaatagaa
     6421 taatgtcagc agattctttt gccacgtcca cggcggtatc caccgaaata ccaatatcgg
     6481 cggctttcat agctgcagca tcattaatac cgtcacccat gaaaccgacc gtatgaccat
     6541 tttcacggag aacagaaacc acacgggctt tctgatcagg ggttagcttt gcaaatacat
     6601 ctgtagactc tgccactctt gcaagctctg catcgcccat ttgttccaaa tcagaaccga
     6661 gaagcatatt gcgaacctct aatcccacct gcttgcagat agttcgagtc actttgtcgt
     6721 tgtcacctgt caaaattttg gttataacac catggtcttt cagagcttta atagcatccg
     6781 cagtagattc ttttggagga tcaaggaatg ccagatatcc aatcagtacc atatcacact
     6841 catctttaac accaaatgcg ccgattgggg aaggattact cttctgtgca atagctagta
     6901 cgcggaatcc cttatcgtta agattgtcca ctgtctccag aattctgtaa cgaacgtcat
     6961 cagtcagagg ctgcactcct ccattacact ctgcaaacgc acaaatagag agcatttctt
     7021 ccacagcacc ttttgttacc atctgggtct tacccttatt atcctgtacc actgtagtca
     7081 gacgacgacg tgtgaagtca aaaggaatct catctacttt cacatagttt tcagacaggt
     7141 caatgagacg cgaatctgcg gcttcctctt cctccgtctt atggataatt gccaaatcca
     7201 tcaggttttt atagccagtc tggaagtaac tattgaggta agcgtgacgc agtactcgcg
     7261 tatcgtcctc gccatttaca ttcagatggt attccagcac aaccttatcc tgggtcagcg
     7321 tgccagtctt gtcagtacag agaatatcaa tagcaccgaa gttctgaatg gaattgaggt
     7381 ttttaacgat tgtctgcttc ttgctcatgg aaacagcgcc tttcgcaaga caggttgtta
     7441 caatcatcgg caacatttct ggtgtcaaac caacagcaat agaaacgccg aataagaagg
     7501 ccgccaacca atcgcccttg gtgataccat tgacaaagaa caccagcgga accataatga
     7561 gcataaaacg aatcaatacc caagaaacgg cattgacacc cttggtaaag cttgtttcaa
     7621 ccgcttctcc agcaactgcg gacgccatag agccaaacag agtatgatcg ccaacacaaa
     7681 caacaacagc tgttgcgcta ccagaaatta cattactccc cataaaagca atgtttgtgt
     7741 aatcagtcac gctttctttc tgagcactta cattgggtgt tttttcaata ggttcactct
     7801 caccagtaag acttgcctga ctgacaaaca aatccttcgc atccaaaata cgaacatccg
     7861 ccggaatcat atctccagca gaaagatgca caatatctcc caccaccaaa tcatccatag
     7921 gaagttcttt tttttcatag tttctacgag taactgtaca agtggtcgta atcatggcta
     7981 acaatttctc tgctgcattt ccgcttctgg attcctgtac aaaacgaagc gtaccggaaa
     8041 tgaataccat tgttaaaatg attacaacag tcagggaatc aaagtcctct ggcacactgc
     8101 caaacagaga aaaatacgga aaaatcatat ctgtaattgt ggatactaaa gccagacaaa
     8161 ataaaatggc ggtaaatgga ttgataaatg cgccaaccag tcgttttgcc agagatttct
     8221 ttttttcatg agtgacttta ttggtaccat atttagcacg acttacggat acttcatcta
     8281 cttctaagcc acgaagtgtg gtatgaagtt tttttaaaac ttctttaata ggattggttg
     8341 ccgcaaattg aatgcggcgg ttctgttcgt cacggatgac tgctttttct acagtctgac
     8401 gaatagccat acgattttct tttttgttca ttggtcttac ctccttgaat tttcataggg
     8461 gcaaggaata ttatatgagc gacacggaat ctccaaattc tcatataata ttctctgcct
     8521 tcgtggactg acatcagagt ccatgtcttt cacctcacaa tcttaaaaaa atatctatgt
     8581 gaaacctcaa tgtggattat tggttgcgat agcggacact tttttcgata taccagacat
     8641 caaagccggc aacaatcagc catgcgatta ttgcaaatac aaaccagtgg tttgaaaatc
     8701 ccggcaaaaa tcctttcatt aagaatataa tcccatttaa cgcaatcatt tctccaacat
     8761 tacgacaaag cgggacaata ttaattttat ctttctcctc ctgcggcata tttttccaca
     8821 gggaaagatg acgatatcct tttccaaagg ccaaccaaaa gcctgcaaga gtaaataaaa
     8881 ttccaaaaaa gatacatgta aaatccatcg tttgttcctc ctttcaatgc ttaaacctgt
     8941 ttcttagttt tgtcagcttc agaagtttaa tgaagagcac aataatagta acagcaagaa
     9001 taaaccagat cacaatactc acctgatacc atatcttaaa gattaccatt ctttgttcaa
     9061 agaaattcca acccaaatag ctacataaga ttgtaaatac agggtagaaa gcaaaaagaa
     9121 ttgctcgttt caaatcttcg atttctctcc tcactcacaa cacctcccaa ccagcactaa
     9181 tcacttccgg aattaccaat acctgcccaa cgattccttc taaaatattg tttttggatt
     9241 ttccgacaga acagtattct gcgacaatct caaccttgtc accaaccaca tcaccgcttt
     9301 ccagattgtt caaaaagagc gtcttacagg aattgctgtt aatcagcaat aagcgtatat
     9361 cctgctctgc cttttcctga catgtaaccg aaatacgata ctgcttttca gattcatcac
     9421 tggaagtaat tgggtgaaac tttcttgcaa agggacgtag aatcaggttg gaaccaatta
     9481 aaatagtagc ggcggtgatc gccattgcat acattcccgt acttgcaaga attccaatcg
     9541 ctgcagtaca ccataaggtg gcagcggtat tcattccacg tactgtccct ctgtccttga
     9601 aaataacacc actgcataaa aaaccaacac cggatataat actgcttccg acacggaata
     9661 cctgatccga accgtagagc ataggaaaca aggtaaagaa acttgtaccc atgcagatta
     9721 acacattgat acgaatacct gcaggatgac cagtcaattg ccgttctaat ccaataagaa
     9781 atccaagtgt taaggagagg gcaattctca aaataaaatc tgtgtaaaac atatgaaaca
     9841 cctcccttta actactaaca gtatataaaa aatccaaata caatcctatg gctaaagtct
     9901 tgcgattttc ttgcgatttg gtaagaaaat agacggactg aaaccgaaaa tggtcttagt
     9961 ccgtctttgt catatctgat cattaaattt gtatccaata ccccagatgg tcaaaatata
    10021 tgtgggacaa tccggagcag gttcaatctt ttttcgcaac ttccggataa aagccataat
    10081 gttgctgtta tccagaatat aatcttcctc ccatacggca cgataaatct gttcctttgt
    10141 aaaaacttca cctttgttct ggacaagaaa gtacaaaata tcaaattcct ttggagtcag
    10201 gttgacttca gaacctttta tcagtacttt tctgcctctt ggataaattt ccagatcccc
    10261 tgccaggatt ctatctgaca gagtacccac tggccaatcg ctttcttctg atgctcctaa
    10321 caataacgaa gatacctctc cacgaatcat ctcctgaata ccagaaagta aatccttcgc
    10381 acaatcactg tccggtggat ctcttagtag tttttctaat agccagattt caagagccga
    10441 atccatcgga atataactaa tattcttttt catcatgaat gcctcctctt aaatcaactc
    10501 ttgatatttt ttcttataaa aatatttggc tactgaattc agcagcatat agagagatac
    10561 caccagcagt aaaaatacga aataccaaag aggtaatttc gtcagtccaa acaacgacgc
    10621 accgccgaca aatgtaaggg aagtaaaagc aataatcccc actagagtta tagaaatgac
    10681 cggtgcagat gccctgctct ggaaaaaagg aatcttggaa gttcgcagaa aatgtaaaat
    10741 caaaacctgt gtccacatag attccaaaaa ccatccagtc tgaaacagtg ctacatactg
    10801 aagttgcagg gaaggatctg taagctgcag ataggttgcc cctccacata gcatcggaca
    10861 taggaaataa tacaaaaata ggaaggtgac aatatcaaac agagaactga tcggtccgaa
    10921 agacagcata aactgtctca gtgttttgcc ggaccagtct cttggggaca gcatctcttc
    10981 ctcatctaca ttgtcccaag gaagcacaat acacaacgta tcatacagca gattcaaaag
    11041 cagaatctga attgaagtca taggcaggaa cggtaaaaag gcactggcac aaatgatgga
    11101 aaaaatattt ccaaagttag agctagcggt gattttaata tatttcagca tattggtaaa
    11161 agtttttcgc ccctccatta caccttgctc caaaacattc aagtcctttt gcagcaaaac
    11221 cacatcggca gcatcttttg ctgcgtccac tgccgtatct acagagattc ccacatttgc
    11281 ttcattcagt gccggaatgt cgttgactcc atcaccaaga aatcccacgg aatgaccatt
    11341 atcctgcata gcagagacaa gacgcacctt atgtcccgga gtaagctctg caaaaacatg
    11401 agtatgttcc acagcctttt taagttcaca gtctgtcatt tcatccagtt gagtaccagt
    11461 taagatacgc tctgtataaa tacccacccg gcggcaaaca gacacagcaa tcgctgcctg
    11521 gtcccctgtc agaatcttag ggataacttt taatcttttg agtgcagtta cagactcctt
    11581 tgctgtctgc tttggtgcat caaagaagga tagatagcca actagagtca tgccccattc
    11641 gtcatcagga gttattttct tttgcgctcc cacatttttt cgtgccaccg caatgacctt
    11701 cattccgtcc tgtaacattt cacctactac agaagataca ctctgtctcg catcctgccc
    11761 catggggaga agttttccac gatattctac atggttgcag cgtgagaata tatgttcaat
    11821 atcacctttc ataataagct gactattccc attgctatcc tgtacaagtg tactgacaaa
    11881 cttacgagca tagtcaaagg gaatttcatc agctttttgg aattttgtca gaagatttgc
    11941 gtaatgggct tcccgccctg gcatggtatt gcaggcaaga atggcattat caatggtatt
    12001 gcagacacca gaatgatagc agctattcag ataagcaaga tcaagaacct ctgcattttc
    12061 atttccaaaa atatccatat aatattccag caggatgctt tcattggtaa gtgttcctgt
    12121 tttatccata caaagcacat ccatgctacc aaagctctgc atggcattaa tatccttgat
    12181 aatggtctgc tttttgctca tagcaagact tcctttggca aggcaggctg taataaccat
    12241 aggaagcatt tccggcatca gacctacagc aactgacagg gcgaaagcaa aagattccat
    12301 ccattttcca tcagtaatcc ccagtaatat aaatacaatg ggaactaata tcgccataaa
    12361 acgtatcatc acccaggcga tggaatcggc tcctttttta aaggaatttt tatcatcaga
    12421 atccggtttg gtaaatcctc catacagggt atctttgcct actgccagta caatgccttc
    12481 cccttttcca ctgatgactg tggttgccat aaaagcgagg ttttcaagct gagtcagtgt
    12541 atcctgctct ccgtaactga gttttcggca gctcttttca atgatggcgc tctcgccagt
    12601 aatcgcagcc tgagagataa agagatccgt aatcttcgtc aatctgatat ccgccggaac
    12661 acgatcacct gcagagaata gtacaatatc ccctaccact aattcttcgc caggaatctc
    12721 tattaacttt ccatcacgcc tcactgtgac gctttcatga actaggcgat caagctgagc
    12781 agcagcgctc tttgctcgca gctcctgaat cagacgaatt acgccactaa ttacgatcat
    12841 ggaaaagatg ataatggcgg tagtagcatt tctcgcaaaa ttggatgcta cgaaaacatc
    12901 cgtaacaaga gaaacaatgc ccagaacaaa aagaatcaca tgaaacgggt taataaatgc
    12961 ccgtctcaac cgttgcatcg tcgtatcatt tttccgccca ttgaagctgt tcgctccgta
    13021 tttctcccgc attgaaccga tttgctcaat ggataaacca tccggagatg agccaatgtc
    13081 tcgataaatt tctgatgttc tacagtatgc gtattttttg atacgactat caaatagtgt
    13141 tgcttttgac acgaaacatc ccctccttta taagtataag taataatatt ttaacacagt
    13201 gttctgaaaa tgctatattt atattcttgc ttttttcttg caatttactt tgatatggca
    13261 tttttcagct cgatcaaatc cgtctcgtta gggcgagata aatccttatc aaagttttca
    13321 accattcctt ctaaatttgg agcacggatg gatacggcaa gcattttctc atagcgctct
    13381 cgcacataaa taggcatttc cccttgacac atatgagtgc tgacaaactt cttcttggtt
    13441 ttcaccttga ccatgtatca aatttaaatg aactacttag aaaagttgct cataataata
    13501 tttgtattat gagtgataga atgacaaaag tggcagtatg gaaaccgagt gtaaaaacaa
    13561 tacaattagt ttgtatggaa tatctgaact acataattga ccactctgta atttatgaaa
    13621 aaatacaatg cgcaaattgg aacgggacag aagaaaccaa tagtattttt aataattccc
    13681 cttcaccatt gattactctt atctattctt gcgatttaca acaaaataaa acaacataaa
    13741 ttttaaatac gttgactggc ataattcata tgtatagtaa gtctacaatt aagatgcgct
    13801 ttttctaatc caaatatatt aagaaaaaaa ttttgcgaag ccattaatac tttgtttaag
    13861 atgtctttca taaatataaa gaataatgct cttaacaaaa gcgtgcaaat tcctaaagaa
    13921 atgcacgctt tcaataatta tcctataatc ttccaattgc tctccttatg tagcactaat
    13981 tcaaactgcg atacctgtgt tgcctttgtc tgattatcaa tgaatttcac ggcaaccttg
    14041 actttcacat tgtccccatc aaccgtaaag atagggttta ccaattcaga atagaggtag
    14101 tccctgccga tagactcaag cacatttcca gacacatagt aagcaagctc cttttctgtg
    14161 gctgttgggt atagcttaaa gaaagtttcc agaaatgcag tagcgtcatt tatggtatcc
    14221 gcgtctacac ttgcgtctgc ttctggtgtc tttggttcat agtctgattt ctcgattgct
    14281 ggtgcaaggg tagggttctg aataattacc atattcccgc cagcgtccac atgaactttt
    14341 acggtatagg ttgccttaac cgctgttgtc tgttccccct cttttatctg ctgatctact
    14401 tcgtaggtag cggaaaaagt gtccgttcca gactgttcaa tgctccatac aatcacatct
    14461 gtaatggcag agctggtcgg tatatccgtt ctaatggtat ccatattcaa gtcctgcaat
    14521 tcctttgtca gataaccgct gattgcctgc gtccttgcgt caatcgcttc tttgctgtta
    14581 ctccatgtgt aataggactt tgcaaaattc ttcacgaaat tttctatccc gttggtgtcc
    14641 tgcaagcgaa gctcaatcac ttctttttca tgggtcgtgt gctggtcaat agcggtaaaa
    14701 ttcttatata ctccaaagct cacgcttgca ataagcacca cccacaatgc aatcacggtt
    14761 ttcttatgtg tgcctacctt gacagtacgt accttttttt ctttgacatt ttctgtctgt
    14821 ttcttattct tcttaaacat atttttcaag tcctttctat tgttttactc gtcctgcacc
    14881 gattaagtgc tgttgccagt aactactact taggtctgta tatcctatcg ggtcgcctgc
    14941 atggtacatc tgattatttc ccacatagat accgacgtgg gttacatacg aaccagcgtt
    15001 ataggtggaa tggaaaaata ccaaatcgcc agcctttgcc tgcgagagtg gaagatgttg
    15061 ggtagcgtca tactgggctt gtgccgttct cggtaaggag ataccagctt ttccatagca
    15121 ccattgcgtc agtcccgaac agtcaaagga agtggttgga gaagaaccac caaacacata
    15181 tttccaccct tgatatttca acgcttcatt cattaccttt tgtgccagct ctcccgatac
    15241 ctgcggaaca gttaaatact gattgactaa ttccacatag aacatatttc catagccata
    15301 ccgccagcct ccgttcttcg caacggctat cgggttggta taggttactt tctttccacc
    15361 cgatttctca cgggcgaagc tctctgcaag attaaaagtg tgtttctttc cgtttcctgc
    15421 cacatagccc acatagccac cgccatagtt ataggactgt atcgctacat tcaaatcgtc
    15481 gatatcttga tttttgcagg aagaaagcag ggacgcaaaa tacttacacc cctgcttgat
    15541 tgagctttcc gtatctaagg aactaggcgg taaaccaaga ctttctgaac tctgcataac
    15601 atcttctgcc gtaccgccac tttctacttg aatgatagcc agtagtacat tgacgtactc
    15661 ggagataccg ttttctctgg cgtatttttc taccataggc tgatgtttca aaacttctgc
    15721 ggataagttc atacccgtaa tgccagaaga aaagttgctg ttttcgtcgt cgctgtccgc
    15781 actaatcagc accccaaaga aaagcaccag agaaaagaga ataggaaaca gacttccaat
    15841 gatagcgata tgtttcagtt tcattttttc ttctgtcctt tcttcgttac aagattacgg
    15901 attttctctg tggtctgctg gttcttctgg acagtctggg tctgctgaac ctttgtccta
    15961 cggtctttgg tgtaattctg gcgtgtttcc tttgacacgg taactttttc tacattctgc
    16021 ctatatgtcg attgggtcgc tttcccgtca ggagtactag aagatagcgg acgttctttg
    16081 acaccgcttg tcttaactgg ttcgcttgct ttcgtagtcg gagttgtggc agggcgtttg
    16141 acttcctgca ttttttccgc acccgtcttt gaaacggttg aagctgtggc tggtcgctca
    16201 tggggacggg tagctcccgt tgtcgctgat ccgtcagcct ttcgctgtgc ctgccttgct
    16261 tcttgtgcct tttgaagctc catacgcttg acagcgatac ttttcttatg ctgttcctgc
    16321 ttttccaagc gtcccgtctg tctggactgc tgttcctgca ccataccacg cttgaaatca
    16381 gacacgctgg actttgcctt ttcctttgcg gaatacaccg cataagcggt ctgtgtgggc
    16441 atatccttga tattctcttt gacagcgttt gccttgtctt tcactttatt tttcgtatct
    16501 aagacagcac ccacctttga gcctgcacgc tgtcccatac tggaagtggt attgccccga
    16561 ttttctttag aagccgtatt ttttctttcg gatctcttgc cagcaacggc acttccagct
    16621 accgcaccag ccacaccgcc cgaaataccg ccagcactta cagcccttgc aatacggtgt
    16681 tccatacgcc tagcccgatg tcgcatgaac agatacggtc tgcggaatat cctgcgtccc
    16741 atgctttgac tgtcgccagc gttgagagaa aacatactca ttaagtcgcc cagcttcata
    16801 tagataccag cgaaacatac tatctgcaag aacgccacca tgaaaaacgg atagtccgtg
    16861 gatatgttat aaaacatact ggaaatgcta aacgcaaccg ttataatgag cgttattcct
    16921 gcccgtgtca ttatggtatt aaataccctc acgattgcct gctttgccat gctttcatag
    16981 ctcggtatca tggaaagtag aaagctgata ggtaaaaaca tagcgaagat aataaaaagt
    17041 atctggctga acaacatcat acccgtaagc aagaatacaa atatcgtaat accaagatta
    17101 aagaacaaga ggaagaacac catacctaaa cggtttacca cctgcggtat cgtcagattg
    17161 ttgttgtcgt tgtcctcgat ttctgttttc acgacttctt ctctggtctt tccgtcctcg
    17221 tcctctggac ttgccgatac gagagcttcg acacggtctg tcccgatttc ctctgcgttg
    17281 ctgtttccaa actgtaagag tagccacggc tgttgtactt gaatagaaaa taggctgtcc
    17341 cgtatcaagt ctacgctgtc cttgccctcg ctgtcagagt tggggagcat gatttttgtt
    17401 cccaaatcaa gcgaagcggt actgatgtct gatgaaaatt catttatctt cttgatgtag
    17461 tcgggagcgt aggcaataaa cgaagcggac aacacgaaca ccaccacaaa gttgataaca
    17521 gcgtgaagtg ccttgctggt ttcccgtttt atcagtcccg tataggcaac atacattccc
    17581 accactaaga taataagaag caggaaacca acatagaagc ccgtagaaga aaagccgttc
    17641 tcggtaacgc ctgcaagggt ctgtatgctt tttccgatac tgtctgccat atcgttaata
    17701 aaatcaagtt tataggcttc ctgcaccaca tagccagttg cattgcttaa ataaaggctt
    17761 atcgtccaga caaagttggt aatgcagtaa agcccgtact gtaccgattt tccgataccg
    17821 tccagccagt tccacggaag ccacgaccag ctattatcga cgaaaaaatc aagctggtag
    17881 ttggaaagcg gatattttga atatagattt tctgcgttta tggtatcgtc cacaagcccc
    17941 gtcgcatgag ccaccgtccc cagaagtgaa agcaggataa gggaaagtgc caccacgaac
    18001 agagccattt tgagaaagtg aagtatcttc ctttttgtga acgcactctg tatcctttct
    18061 ttcatcactc cacctcattt ctctgtacgg gcggtctagt atcaaaggcg tgtagtaatt
    18121 cttcaaagac tgggtgtatc tgcaccacac cgacacgccc gtataagtcc tgcaataaac
    18181 attgtccgtt ctccaaatca cgcaagcgtt tctggttgtt ttcgtcgtcc ttgtcgatac
    18241 cgaaaaattc taaggtctgc tttatctcgt tgatgtcagt agaacgaaat gcaaacttca
    18301 aaccgatatt gtttttcaga ctttcctttg acacgtcata ggcagactgg gtaacgaaat
    18361 aaacacctgc ctgcatagct cgtccagcac gaaccagctt atttgatagg gtttcgcctt
    18421 gtgccacatt taagaacgcc cacgcttcgt ccaaatctac aatcttaaaa atgcttctgt
    18481 ccgaatggat aaaatcaagg gcaaaggtac taatcacaat cagcatagac accgacaata
    18541 attcaatggt cgtgtattcc tcaaaagtgg tatctttatc tggcagtaca aggtctgcta
    18601 cttgaatgat attgagctgg ttatcaaggc ttatagcatt ttctaccgtc ccgtctgaaa
    18661 acagcaggtg tgcaaagtcg tagtccgtga agctgtcgat atggtctgcg atattgcgtg
    18721 agatagcggt atcttctttt ctcaattcct caataacgtg taacagtcct ctattttcac
    18781 tctgggtaac agaacgcacc gcttttcgta acacggggaa tttttcgccg tccctagagg
    18841 aaatacccgt aaggaatgtt aagatgtcga ttgccagact ttcagcgtct ttcacattct
    18901 tcataatcac aaatgggtca agaagtcctg cattgtcctt gtcgctggta aggtttacga
    18961 tattgatttc atgggctatc tctgggagcg tttctttcca gttgccacgc tcacttttag
    19021 ggtctaacag aagtgcttga ccgccaaaca gcaccgcata atatacaagt agattgttgc
    19081 agaatgactt tccaccgcca agacttccca caaaagcaga agcaagggca ttagtaactg
    19141 tgccttttac tccctgcgaa gctaaagacg gttgcaggta cacatttctt cccgtatcaa
    19201 cggaatagcc catatagata cccgtgtttt cccctaactg ctgggtcgca ccaaaaccaa
    19261 gcccagccaa gaagtctgac tttacatact gcacatagtc attgatatat cgcttgctgg
    19321 caggtaaaaa ttcagaatga agtcccaaca tatcgccagc aggacgcacc agttttacat
    19381 tgaggtcgtc gtaaaagtcc ttgacttcat cacaacggcg tttcagctcg tcaagatcgg
    19441 gtgcagacac ccgtatgacg tagcttaact tatacatact ttctttgctc tggtctaaat
    19501 cggtttccag ctcgtccacg ctgtctaaag cgtccaccac atttgagctg gtttcacttc
    19561 ctgcttgata ggcgtgatta tccaaatctt tcaattcctt tttcttgttg cggactgtcg
    19621 ttaatgcctt acggttctcc acgatttcta cattcataga agtatcaacg gggaatgtga
    19681 attgctgttg ctggaaatag aagatttcag aggacggaaa atccaactcc ccgacaatta
    19741 cattgacggt aaaataggac acatagcttt ccttgtcctc atgttccaat cgtaaatacc
    19801 gctggctttc ctcaatcaca caccttgtcg gacggataag gtcgtagtat tttatcagcg
    19861 tttctttctt caatttcttc tttggtagct ggtactcata atcttcatag gcgataccgt
    19921 ccctgccgta aagatgttcc atgagatacc caaaatcatg gatttccaag cgacgcacct
    19981 taaagcgacg ggagatttta ttttccagta acttttccat tttcatgtaa cggttgattt
    20041 catcattcgg catggaaaca aaatcattca tcagcgtgtg gttcacttca tgaagaaatt
    20101 ccttgaacgt cagccatgcc gattttttga tgttcttcag attgagctgt tcttccgtaa
    20161 ccatgagctt aaagccaaga aaaaagcggt agtccacttg attgtcccca atcattgata
    20221 ctaacgcttc ggtctgttcg tctatttttt ggactgccac ctcacgaagt ttgcctgtta
    20281 ccagtttctt tgactgctcc tgcatacttc taatggagct ttctgtggca atctgcaacg
    20341 catgaatttt tccctcacgg gactgtgcga ttagctgtcg aaaactgtca tgcacgataa
    20401 atttctgctc tgcggataga aaagaatagt tgtacggtat cagctcatag taggcgaaca
    20461 cctcattgtc cttgttccag acaaggttat tgtcaatata ttttatcggg aacatagttc
    20521 acactcctta ctgccgtgat tgtttcattc aatatctgct tatgcagttt tacggctttt
    20581 cctgcataag tgattttagg tcgcaaggca taggttatct gtgatttcaa aaagctgtac
    20641 ggcttctttc cgtcaaaggt tttctgcgac ataaaccaag tgagagcaac gggaataccg
    20701 aagtatttga gaaatgctcc ctcaatcatg gaaagtgggg gcatatcccc aaacagaatg
    20761 atgataaatt ccgtaatcac aaaccatgta atctgtgtaa aggtaacggg aaagggtaag
    20821 ttaaagtcat tgattgcata taagactttt tccacgttcc agataccagt gtagctttta
    20881 atctttttca agttctttca gcccctttcg taagttcttc aaagagaaaa ggacagccat
    20941 tttcagactg tcccttaaag agaaatacgc tgtcagtagc aacaatgctt gttgctgatc
    21001 ttccagcgtt aatatggtat ctcacagata cctcggcttg tttcaatgaa tcgaccaccc
    21061 atatccaaat ctcgcccgta ggcttcatag tcaatatagt tctgtaagtt agctggaatg
    21121 tccccaagtg cgttcaattc gtctatgtag tagtaggcaa catctgtcat ggtttcacaa
    21181 tcgggataaa aataaatatc gtccttatgt tccacgactt cttccagcgt cccatagtgg
    21241 ctgataaatt cgtccagaca ctctacgata tagtcgggaa gttcctctat catttcatac
    21301 atttcattga gttcttcaat ggaaacatat tcccctatgt cgataggaaa gttgtcggta
    21361 tcatggacag cgtattcttc gtactgttca ttcaagccga ttttttcttt tacatcttcc
    21421 tcgtcaatag ggaaagtgaa ccacgcaccg actaaatatc cctcattgta tctgccaaga
    21481 ttagcaatat aaaccgccat atcatcaatc ataagcacca cctcatttcc tactctggca
    21541 gttcaaagat accgtgttcc gttactaaaa attttccgtg ttcctgcaag tgagaagcat
    21601 aggcttcaaa gtcaaaatag tattcttgac agtcctcgga taaatgtttg aatgtcgggt
    21661 cgttcatcag cttttgcctt gcaacatcaa tcatgctttt gcagtcggga taaacggtaa
    21721 tcacgttcct gcaaatgtaa agtgcttcta aattctcata cacggtaagt agtgatacat
    21781 attcttcctg catatcactt gaaagctggc ggtacataaa atctaattcg ttgagctgat
    21841 acacgctggt gtgttcgtgg acttcatcag cataaggcag taccttttcg ataatgcggt
    21901 aatccccact ttctgcaccg acacctaatt tttcttcaaa ctcggcaaca tctatcggca
    21961 ggtcaaacca gtatgatatt gtttcttcgc cagttgttcc tctcgtttcc accagcaccc
    22021 ttgtttcctg cattgttcct cacgtccttt ctgttgtttc ctcacatctt ttatggtctg
    22081 gtacgacata ccaaacacat actttgaaaa atcttctaac tgtttttctt cataatcggc
    22141 agggttcagt cgtttcattt catgccacac tttacgcttg taagagggca ggtcggaaat
    22201 gtattcacag ccgacttttg cctgcatatc cttaaaaata tcgttcattt catcactcca
    22261 atctgaaatt ttggcaagaa aaaagcagtc aatcctaaga ctaactgctt tgtgtatatc
    22321 tggtattaga ttatgaaatt gagtttatca attcttgtac ttcattaaaa aatctggata
    22381 aatgaaaacc atctgcaacg gcatgatgta tattcattgt aagaggcatt atatatcttt
    22441 ctcgctctaa ttcgtattta ccccaagtaa taactggtgc aagaaatttc ccttcgtcaa
    22501 aaacatgaac atcaaaatga ttgtatttta cccatggcaa acaagataca tcaaaaaagt
    22561 tcaaaggttg atttgctacg aatgcacgtt ccattttatg tttctctcta tctaacataa
    22621 atcgttcatg aaattcaaat atgctatcag aaaaatctgt aaccattttt gtgaaattct
    22681 catcttcttt atgaaattca gcataggacg gggaaatata gtcccattta attaaattac
    22741 ctttattgtc ccaactatat ttaaactcat catgttcatt aacgaccttt gaaacaaccc
    22801 atatcatagc tggataaaat ttcaaatcat ggctttttga aaattcaatt agatttgtta
    22861 catcaatatc tacggttaag ctcataacga tacgcatatc atcaatgtaa ctttgaaaca
    22921 atttacctct attccatttt tctaaatcaa tttttgtata tttatattcc atgtccattc
    22981 tcctttacat tttgaaattc agtaaaatgc aaggctctct ggataacatt tcactccatg
    23041 caagtctatt ccattaagcc ttgtatggag ataatacaat acacaatttc ataatatccc
    23101 tccttatcca ataaacctta gtttattgtt ttcatactca gattatacca ttcatatata
    23161 ggctctacaa taaaaatcat tatgcaccaa taatcttatt gaacagctct aacagtacat
    23221 ctttcacacc gccagcgttg aatactaagc cgacagcaat aagggcaact accaagaagc
    23281 caataagttt tgaaaactca cgcttgaacc ctaagtagat accgataacc acaatcgcca
    23341 taagcactaa gctctgtgca tttgataaaa accattgata caaattttgt ccgaaattca
    23401 tttaattgtc ctcgctttct tctaattgtt tcatttcata gtcagcttct ttgccgatac
    23461 tcaaaataca catcaagact acgccgatac ccattcccat agataccagc aggaagtctt
    23521 ttactaattc ccacattttt tatcactcct aactttccac caaatctttt gcaggggtcg
    23581 tctgctgttt gattatcatt tcatgctttt cactcaaagt tgcctgcttt tcaatcgttt
    23641 ccatatagtc agtcccgttt cccttatcaa tctttttcag cattttcaag gtaggtgcta
    23701 cctgcctttg tacccaccgc aatgtacggt ctaaggtgta aggctctggc tttgtcgtca
    23761 gcttcaagct ctgtctgtta tcgccgataa accaagccca gcggtcattg agtttccagt
    23821 cattttttcg cttgtctggt tcttcatcaa caaaccgcac atactggttg atgatagaaa
    23881 aggcggtctg ttctgcgtca taataggtca gcaaatctcg tactgcataa taggcacgct
    23941 catttctaag ccgtatctca aaacggttga taatgtcggc ttcattaagc ggtgtaccca
    24001 acttgacgta ctgctcatag tccttttcat agatacagaa atatacatct gatttcagcg
    24061 aaccaagata aagagtgcgt cccatatatt ctctgtcgtc ctctctgtgc ttgataagct
    24121 cgcccgactg gtaaaactta taacttctgg actttccgat atattcccgt ttcctgcatt
    24181 tttccgcaag ctctggaata tccaaaatgc ccgtatggtc gttgatagca aggtcgatac
    24241 gcttcatcac gccaccgtct acgagtgcgt ccatgaggaa gtcataccag cttctttgct
    24301 gtgccaacag gtaactttca aactgcctgc aaccacgccc ctttaactct aaaaggacac
    24361 ctttttcttc gtcagccgac gtatagataa agatgtcccc taaagagtaa tgctccgtat
    24421 agctgtaatg tccgtaatct tcatggagca tatagttgat attcagtttt aatatatctt
    24481 tgatgatgtg ctgtatatcc agcgtgggaa aacgaatttt tacataatca aacaacatgg
    24541 taagcggtgc ttctggattg aaccttgcca gttccttatg cagagtttcc agaagttcct
    24601 ttgacggctt catttttccg ctttctatct tattgagata ttcccttgtt ataccagaag
    24661 tcaccgccag cctgccttgt gagataccgt aagcaatccg tttctcccgt aattctttta
    24721 tccattgttc ttcattcaga accatacccc caatctgtaa agtgtgaagt ttttaggggc
    24781 gacttcacaa ccgatttttg ctaggaaacc atgccagaag ccttatgttt cctatgtttt
    24841 ttgtctattg tctatttgca aacgtacccc tctgttagat accgaggggt tttacctgct
    24901 ggcgtggctt acgccacacc agcaacggct agtccgtgcc gtcgcctttc gcttcgcacg
    24961 tcgccgtccc gtcctgcctt gcttgtgcaa gagaaccgat agtcttcaaa aaatcatgtc
    25021 ctttcgggac taagggcgtg taaaattcgc ttatcacgct tgttcctaca tcacaatagc
    25081 cacgaccctt gatacgcttc tggaaaaact gctttttcac atcagaaccg aacagcatac
    25141 catatcctaa ctcgctgata cgccccaatc ctacacggaa attgaagtta tctctgatac
    25201 cgtccgagaa atactttgcg tctggacgct ggcaggcaac gataaggaaa taacctgctt
    25261 gtcgccccag cataacgatt ttctttaact ggctaagtag gctcacgctt tctttcgttc
    25321 ccagcatttc aaaaaaagcc acatattcat caaagataag aaagcagggt ggcagtccca
    25381 gataggcgta gttttcgcct gtcttgtagt tcgagtgttg cttcatttcc tcacttcgtt
    25441 gtaccatgcc ctcataaaag gaattgacgc aatctatcat ttcttctttg gtgtggtaca
    25501 cgtttcccat gactgttccc aaatctgcaa ggtcagcgtt ctttgggtct aagatgtaaa
    25561 ggacagcgtt ggtatgcagt aaggcttcaa tgagcgtcag cagaaagtaa gtcttaccgc
    25621 caccagtccc accagcaatc agggcgtgag ggagtgcgtc atattcccag acaagatttt
    25681 tcatcagtct aagacagccg ttttctgccc gtacttcatc aatggtaatg cggtttgcta
    25741 tcatatcata aagcagggta tattcaatat aaccgtcatg cagtgttttg tcggttagct
    25801 cacaatacaa gccactttcc aatttatcct ctaaccgtaa aagctggtct tgatatttcc
    25861 ccagcgtaat ttcacagcgg atatgaagca gtcccttttc catttgataa taaatctttg
    25921 gaaaccagac gattttttcc cttgatctgc tttgcaggtc agtaaaaaaa ccgctgtctt
    25981 gtacggtatc ggcttcatac cacttatttt ccagtatcat tcttgccagc ttttgacggt
    26041 gcaggagctt cttgaaactg tcgtaacaga agcgataata cagaaaagcg accaatgcac
    26101 aaacaccagt cgctatcagt atggttatca agttgtaagg ggataacgtc aagccttttt
    26161 ccaacaagct gaaatgttcc caatcggtac gcatgagctg tttgatattc agtagcagga
    26221 gaaccgccac gaatacaaac agaagcgtcc ctatggaaaa gtgatagaca aggtgcttgt
    26281 cgctggctct gatacggtgt cctttgttcc aaatcttacg cataaatcaa tcactccttt
    26341 ctgggtacga aaaaagcagt caatcctaag actaactgct agttacgatt tatttgaaat
    26401 gtgaaatctt tccgtatttt tcgtatgaat atttaagcat ttgataaata tcttctctaa
    26461 gaatatactg gtatgtttct gagattgttt catacaccgg aataggaatt gcttttgatg
    26521 aagtcctttg gttcgatttt atcaacactc tttttgctgg cttagatact gttttatgaa
    26581 cccaatccga attcaataaa cagtgtccca taggtgtacc agaactgcaa tatggttgat
    26641 tttcattctt aataaatcta agcaataatt tataatcact tgaagataag ttatccacat
    26701 ctgtccaaag aaattctaaa ctctgttgcc attcttctgc ttgtctctgt ttgttacgtt
    26761 gttccacacc ttttgaataa ttatgatact gtattttctg taccaaccat attactaatt
    26821 cgatgattag aaaccatacg cagaatagga aaacagcata cccccaaata gtgaatttta
    26881 ccaataactt attatccgta ggtgtaacgt aataagctat aaaagaaaaa actattgcaa
    26941 taactgtcgg tactaaatac ttttcaagaa atatctttaa taaatctaat aacttttcac
    27001 tcatgcatct atgcccctta attaaaaaat cacattaaaa atattatacg atttcttaat
    27061 tgcagaggca atcaaaatat atttgatgaa ctaattattt tttcgtttgt ccctgcggtg
    27121 tatggttctg gggattgcct gcgttttgat tgcctttatt cttcaacaca atatcctctg
    27181 cctttacata ccagtccaca tctgcacccg tataggtctt tcttgatacc gtatcggcta
    27241 ctggattgac aagctccaca actgcattgt acggaaattc ccttaacggt acttctggcg
    27301 gtacggacac ggggataatt ccaccatgca gactgcactt caaatcatag atacgctttt
    27361 taagctgagt actcggtgtc ccgtcctcgt tctgcaagaa cacatcacgc accgctgtaa
    27421 attttaattc tccaaatgtt ttctctttgt caatgacaaa accgtttgat aatctcataa
    27481 attcttcact cctttacttt tcttcaactg ccacaatatc atcagcaact aatacataat
    27541 cggtatgtcc catatccccg attgcgtaac ctctgccgta taacttcgga ttgacaagtt
    27601 ttactttctg ctcatacttg aaatgctttt caccagcctg cacgggaatt tctaccacaa
    27661 cattttcacc tttctgtacg tcagaataaa ggttatagct tcgtctggct aaaaccctgc
    27721 ggttattttt atctctttca aagataggct cgctttcgcc tgcaaattca agagttccaa
    27781 aagactgtgc catatctggc acgacatatt tcatttccat attgttttac ctcgtttctt
    27841 tctatatttt ataagttgat tgattgtgat ttcttattct ggcggtttgg gaagtaccag
    27901 caatcccacc gatagtaaag ggtaaaataa atgcttacgc acccttgact atccgtgttc
    27961 ttgcaggttg ttggcagaca agccagaata agcggaagtc tgccgtttga cagcttcggc
    28021 ggagagcgtg attttccttt tttcatgcta ttaccgccct atgatttttt cattttacgg
    28081 cgtttgtaaa gatatgttcc agcaagccca ccaccagatg taagcaacat cacaagaaat
    28141 gcaatgacat ttgtactgtc gcccgttttg ggactgtcgc taggtctgct aggttcttct
    28201 ggtgtctgtg gcgtttctgg tttctctggt tcttctggga cttctggttt ttccttaaat
    28261 gtaatcgtct gtccctcgtc ctcaatgtcc ttatgctcgg taactttctt cggctcgtct
    28321 ggattgctta aatcgtataa ttcctcaaaa gttacaagct gtttgccgtc aagagaagta
    28381 gcgtcaaagg taaaggcaac ttccactttc atagtttcgc tgtcagcggt aaaagtataa
    28441 tcactttcca cacgttttcc attgataaga agctctgcat ttttttcttt caacatctgc
    28501 cagcctacaa gtttatactg tgtaccgact tctaaaccct ctaaggttac ggtatcaata
    28561 attgtaatgt cttttccagc ttcaagctct ttgttgccgt ccttgtcggt agcagtcgta
    28621 tgtatcttga tgatacgctc tgtaatcaat acagtttgcc cgtcgtcctc aatgtccttg
    28681 tgttccgcaa tttttacggg ttcgtctgga ttgcttaaat cgtataattc ctcgaatgtt
    28741 accagatttt taccgccaag ctcggacgca ttgaatgtat aagaaatttc cactttcatt
    28801 tcttcatcat cagcgacaaa ggtatagtca ttttctacac gtttcccgtc aataacaagc
    28861 tcggcatttt cttcctttaa catctgccag ccttttaact ggtattttgt gccttttgta
    28921 agtccgtcta atttgacagt atcgacgatt gttacctctt ttcctgcaag gatagtcttt
    28981 tcgccgttct tactggtcgc tgtggtatgg atagatattt ctttttcgta ttcatcagtc
    29041 aaagtcccta agtcaatcac aaggttattt cttgatacca cgatttcaaa aggtgggata
    29101 agctcaaagc ctttgttact gtcagagcgt aattcttcaa tgatgtaagt atcataaggc
    29161 aatgcacctt tgctgtcgtc gggttcagaa gttccaaacc atacaccgtc ctcacttgtt
    29221 ttgcctgcgt tggtattgtg cttatgtgaa gcccagtcag cagaagtgga gaattgcccg
    29281 ttatcatcag ttaccacaat atgactttcg cccgttgtct tgcttgtgat cctaaaggga
    29341 acatcagcaa gacgtttgtg tgtgcctgca ccgattttta cgccctcaat atctccacgc
    29401 ttaatctgat tgtagataga atgggcttcg tcggttaagt ccatgatttt ttcgttttct
    29461 gtgattgcaa aatcaatcgg ttttgcaccg tctgtcaaat atccgtttgg agcttcactt
    29521 tcaacaatac ggaaatttcc ataaggtaaa aggtcggcag aagtagaagc gacaccctca
    29581 atatccgtat ggattgtttt taccacttca tttttcttgt atagcttacc ctcaaccaat
    29641 actgcattat catttaagga aatgatgtca aaagcagtat ctttcaaggt agcacttcct
    29701 tgtggtttgg tatcgcccgt ttctaaatct cgtttctgaa ttttgacacc gccacggata
    29761 actttatctg atacagaaaa ctggttactt ccagataata cggcaaggtc gccgtcctcg
    29821 gtaatctgtg ttacatataa gcccttaatc tgttcggact tatcgccagc ctgcatatat
    29881 gcaccgtcaa gcaagtagcc gtttggagct tttgtttcct caacggttaa tgttcctaaa
    29941 ggaagaaccg ccttaccgtc ctgcatatag aagctgtcgc cagatacctt gtatgcgtcc
    30001 gctaattttg tgatgtaatg ggttgtcccg tcgctgtcag tttcagcgat tgtctttgta
    30061 acccatgtac gagtagcttc ggcaggaaga ttgtctttgt tatagaagcc agcataatac
    30121 ttccatgtaa attccgcacc tgctagagaa gcgttcccct gcggattgtc tttctgtgtt
    30181 tccatgtcaa tcttgaaaag ctcaatcaaa gtatccgtta cctttggtgt atcagatact
    30241 tttaaggttg ctgtctttcc agcttcaacc tttaaggaat atacagtttt atctacctta
    30301 tatcctgctg gtgcggataa ttccttgata tagactgtgc ctgcttttac ctctacaata
    30361 tctgtatttc cgttttcatc agtcgtaagg gtggcaagct gtttcgtgca gtccttatca
    30421 gaaaagacac cataggtcgc acctgcaata gagtaattcc cgttaccgtc tgtaatgctg
    30481 gtattactgg aaaccttttg cagtttcgta tttccaacat tcagtttcgc ccagaattgc
    30541 cctaattcct gcccctcgcc agagtagata taaccgccac attcatagcg tcctttattc
    30601 tctttgacaa aggcttttgc accagagaaa acttcgtcct gcgtagcttt tggtatttca
    30661 tcataagaag ctcgcacgtt gtcgcattgc cagccaagat gtacgcttaa tctctgccag
    30721 acaacacatt gttccaacag ataaacttgt ttgtaattca attccttgtg agcttcgcca
    30781 tactgtttga catactctaa ggataacgcc acatctgaaa tctggtcggc actcatgcgt
    30841 gagcttgcgt cagttctggt cttgtaacca ttcttgaaat ctgtattgat gtcaatacaa
    30901 taggcagttt cgccctcaac tttcatcatg ccctcattga atgtagaacc gatagaaccg
    30961 tcattcatta ctttttcaat gataccgaca cgctctgcac tttccgtcca gtattgcttg
    31021 ctttctgcat gaacgggtgt agtcggtaaa gcagtaacga tagttgcaag agctaagaag
    31081 cccgtacaca atcgttttaa catctttttc ataaatctaa tgctcctttc attttgggta
    31141 taaaaataga cgctcatttc tgaacgtctt acatttaaaa agggatacta ttttaacaag
    31201 tacccctaaa gtttagtatt taattgtttg tgttcccaca ctctatatca actactaccg
    31261 aaacattgat atagtttttt atctctttat ttctgatttt atcgccctcg ctcgtaaaga
    31321 cgatatgctt gaaaaagtgc ctaaaattaa ggatttctac atagttcgtc tttgtagcaa
    31381 cacacaagtc tccacatgtg tagaatgagg gaacatatct acaggttgtg cctcaataca
    31441 tttaaatccg tgaacattta gatagtctaa atcccttgct aaagtagaag gattacaaga
    31501 aacatagaca attctttccg gattcattga aacaatagtc tctaatacct tttcgtcaca
    31561 tccctttcta ggtgggtcta caacgactac attggcagtc ttaccctctc tatacatctt
    31621 aggtacaatt tcctctgcct ttccaacata aaattcagca ttatgtatat tgtttaattt
    31681 agcatttatt ttagcatctt ttatggcatc atctataatt tctattccat aaaccttttt
    31741 agccttttgt gccaaaaata aagatattgt acctatccca cagtaaatat caaaaacagt
    31801 atcagtatca tttaaatttg catattcaag agccttatca tacaatactt tagtttggac
    31861 agggtttact tggaaaaatg ataatggtga aatctcaaac actaagtcac ctatataatc
    31921 gtttattttt ccatctccat atataactat attttctctt cctagaatag cattcgtatc
    31981 tttttgattt acatttacaa ccaaagtctt aaatccaggt atattttcct taagcactga
    32041 agctaattct ttaagatatg gaagtttgtt tccatttgct actaatacaa ccattacttc
    32101 tttagttgta aaacctattt ttgttactaa atgcctaatc aaccccgtgt gagtcttttc
    32161 atcatatata cttaccttat aggcccttat atatgttttt attattttaa caattttatc
    32221 atttatctca tgttgtatta cgcatttttc tgtcgatatt acatcatgag tcttcttttt
    32281 atagaagcca acaattggaa taccattatt cttttgtatt ggaaattgtg ctttatttct
    32341 atatctatat ggattatcca ttcctatagt gtcatgaact tctacatctt ctaacttacc
    32401 tattctcgaa agtacttgtt taacttcatt tgttttcatt tcaagttgtt tattataatc
    32461 taagtcttgt atctgacacc ctccacaatc cctaagattg tcactacaca ctcttttcac
    32521 cctgaatgga gacttttcta ttatctcaac aatatctccc acagcataat ttttctttac
    32581 tttattaatc ctaactttaa ctttatcatg tattaatccg ccctctacaa aaactgtaat
    32641 accattgtac tttcctactc ctactccgcc ttgaccaatg tctactatat ctacaatata
    32701 catctcgttt ttcgaaagca taaatcaccc tccaatcaat ctattatatt taaatcttta
    32761 caaacttttt tctttaaatt tatattaaaa tattgctatt aattaaacta tattttttac
    32821 taagctacaa tattttattt taccaaaaaa aaaggagctt ataaagcccc ttagtaaata
    32881 aatttattat ttttcttata aaactctagt tgaacctcta tataccacgc ctcttgatgc
    32941 atccacagtt acaacttctc catcttttac tagatttgtt atatcagttg cagacacaat
    33001 aactggtata tctaaattta tacctacaat agctgtatgt gatgtcattc caccattctc
    33061 agttactaca gctcctgctt tttctatata attgttcatt tcagcatcag tagcagtaga
    33121 aacaagtatg tcgccttcat taaagtctac acaagcattt ccattcttta ttatacgaac
    33181 tttaccttct accgtttgag tacctacacc tataccttgc acgatttctt cgcttattac
    33241 atgaaccttt attaaattag tagttccact tactcctact ggtactccag cagttataac
    33301 tactaattcc ccattatcta tataatcagc ttgtctagct gcctcaattg ccttttctat
    33361 aacttcatct gtatttcctg caacagaaga cttaactgga tatactcccc atgtaagagc
    33421 taatttattc atagtctttt cattatttgt agtagctatt attggagatt ttggtctaaa
    33481 tttagatacc attctagcag tatatcctga agaagtagat gttattatag ctgatgcatt
    33541 taaatctact gctgttgtac aagttgcatg gcttattgca tctgttacag taacattgtt
    33601 agtaccattt tcctttaata atctatcata atctaaagtc tcttctgttc tttttgctat
    33661 tgtagccatc atttttactg cctctacagg atattttcca gcagcagttt ctccagataa
    33721 cattatcgca tctgttccat catatatagc attggcaacg tctgtaactt ctgctcttgt
    33781 tggtcttgga tttcttatca tagaatcaag catttgagtg gcagtaacaa ctggctttgc
    33841 taattcatta cattttttta tcatcatttt ttgaactatt ggcatctctt cagttggtat
    33901 ctcaacacct aagtcacctc tagccaccat tataccatca gaaactttta atatttcatc
    33961 taggttctct acaccttctt ggttttctat tttagatatt atttgtatat cagttgcatt
    34021 attgttctct aatacttctc ttattgctag tacatcagat gcctttctta caaaagaagc
    34081 agctatataa tctattcctt gacttattcc aaactctata tcacttatat ctttaggagt
    34141 tattgctggt aaatttatct taacaccagg tacatttact cctttatgat ttttaactat
    34201 tcctgaattt tcaacaacac aaactatatc ttctccattt atttctttta ctcttaagcc
    34261 aactaaacca tcatctatta gtatagaatc tcctgattta acgtcctcag caagaccttt
    34321 atagcttact gtacacattt ctttagtccc cataatatct ttcatagtta tagtgaactt
    34381 ttgcccttct tctaaaaata cctctgggtc ttcaaagtta cctgttctaa tttctggacc
    34441 tttagtatct aataatatag caactggctt atttaatttt tctctaactt tctttgccat
    34501 atcaattctt tctttatgtt cttcatgcga accgtgagaa aagttaaatc tacacacatt
    34561 tagaccattt tgcataagtt gagttaaaac ttcctcactt tgtgatgctg gacctagtgt
    34621 acaaacaatt tttgtcttct ttacattatt taacatattt gctcctcctg agatattatt
    34681 ccacagattt atttttaata ctaaaactta tatagataat atttttgcca tctcataagc
    34741 ttctttatca aatactttct tttgagctaa agcttcactt atttctaaat caattatttt
    34801 gttttctttt attcctacaa ctctagctga ttttccatct aataataatt ctactgctct
    34861 tactccaagt ctacttgcta gtattctatc agatacagtt gggcttcctc ctctttggac
    34921 atgccccaat acagtgactc ttaaatctgc tcctgactct tttttaagtt ccttttctaa
    34981 atcactagca cttccgactc cttctgctaa aacgattata ctatgtctct tacctctttt
    35041 ttgagtagtc tttaatctta gagcaacttc atctactgta atttctactt ctggtactat
    35101 tatagtttcc gctcctcctg caagacctgc atataaggct aaatctccac agtgtcttcc
    35161 cataacttct actatgttaa ctctttcatg agatgatgat gtatctctta tcttacctat
    35221 agcatctata atagtattca ttgcagtatc aaatcctata gtataatctg tatatgctaa
    35281 atcgttatct atagttcctg gtatgcctat agctgggaat cctaagtcac taagtttttg
    35341 agctcctgca aatgaaccat ctccaccaat tacaactaag caatcaattt tatacttttt
    35401 aagaattttt actgctttta atctaccttc ttctgtttta aattcttcac atctggaaga
    35461 ttttaatata gttcctcccc tgtgtataat atctccaaca gaagataagt tcatttcagt
    35521 taaatcttct tctagtaatc ccttatatcc tctattgatt ccatatactt tgcatccata
    35581 atatattgct gatcttacaa ccgctctaat cgcagcattc attcctggag catctcctcc
    35641 gcttgttagt aatcctatag ttttcatttt ttacctcctt ggattttatg tcaatttttt
    35701 attataatca ttgttattgt attctaatgg actttttttg tccctatatc actttttaat
    35761 cccatcaaga ctaaaaaaat taaatgtcct taaatgtcca ttttgtgata ttatatcaca
    35821 aaacggacaa tatttttcat attattataa tatatttaga tttttatata aaaaatcaag
    35881 cttttacttt tatgttatct ttaggaagta actcttctaa gttatttata aattcatcac
    35941 atatacaagt caatgccccg gtcattttat atgctttacg tttaccattt atattttcat
    36001 ccatagggta taagtatatg ctgtcattac ctggatattg tttggctatt tctacaatat
    36061 tattagttgt atcggtatca gacatactat ctattttcaa atacaatttt ttaccacttt
    36121 ctggcttaat attttctaca tttctagttc ttcctgaatt gtagtttcta tctgcaaagt
    36181 cagtatcatc atttatatct tttatctctc tagctataag ttttgcattt tcgccttctt
    36241 ttatacttaa tgttcctttt acatatatta tattatcttc attcaaaatg acattatact
    36301 tttgtaataa ttgaggaaaa actattattt ctatagcacc atacaaatct tctaattcaa
    36361 taaatgccat aatttcattt cgttttgttg ttttaatagt tttagttaca atcattccac
    36421 ccattataac atctgtttca ttcatttgta ggtatgactc ttcttcctct tttaatgaat
    36481 ttaattttcc attatccata gatgtttttt cttgtagttc tttttcaaat tgtgataaag
    36541 gatgtccact tacatacatt cccaagactt ctttttcaag gttaagtctc tctctttctt
    36601 cgtactcttg ccttttaggc aaactgtata tttgttgaaa atcactatct tcctcactat
    36661 ctccaaaagc atcaaataaa gaaatttgac cttgaacatt tttctttcta tccatagata
    36721 cactttctaa taaactttca taaccagcca tcaaactagc tctattttca cttatattat
    36781 caaaagctcc acattttatt agactttcta ttactctctt atttgtatct ttttggtcta
    36841 atcttttgac taaatctact aaatctacaa ataatccatt agattctctt tcagcgatta
    36901 tattgtttat tatatttaca ccaacatttt ttacagctgc tagaccaaat cttatattgt
    36961 cgccttcaac tgaaaacttt gaaaaacttt tgtttatatc tggaggtaat acatctattt
    37021 ctagtgcttt acattctctt atatactcaa ctaccttatc agtatttccc attacactgg
    37081 ttatcaatgc tgccataaat tcaactggat aatatgtttt tagataagct gtctcatatg
    37141 ctaaaacccc atatgcagct gcatgtgatt tattaaatgc atatctagcg aagtctatca
    37201 tatcatcaaa tattttatta gctatttcct cttctacacc atttctgata caccctgcaa
    37261 tttctatatt accatcttca tcaaatttac catgaataaa atattgtctt tcttcttcca
    37321 tcacatccat ctttttctta ctcatggctc ttctaactag gtcacttcgt ccgtaactat
    37381 aaccacctaa atctctaacg acctgcataa cctgctcttg atataccaaa caaccatatg
    37441 taacttccat tataggcttt aatttttcat gtagatatgt tacatctttt gggttgcttt
    37501 tattttttat atatgcaggt atagaatcca ttggacctgg tctaaataga gatattcccg
    37561 ctacaatatc ttcaaaattg tctggtttta gctgtttcat aaaacttctc atgccagcac
    37621 tctccaattg aaacacccct agtgtatttc ctgatgaaag catttcatat actttcgggt
    37681 cgtcataatc catctttgaa aagtctattt tttctgtgta gttttttata actctatttt
    37741 tttctattaa atcaagagta tctcttataa ctgtaagagt tcttagccca agaaaatcca
    37801 tctttaaaag cccaagttct tcaagtgttg tcatagtaaa ctgtgttgtg attgcatctt
    37861 gatgtttgta caaaggtaca tattcatcta cgggattttt tgatataaca actcctgctg
    37921 catgagtaga agcatgtctt agcattccct ctatctgttt tgatatattt attatttctt
    37981 ttgtttccgg gtcttggtca tacaattctt taagattagg atttgtatct agggccttat
    38041 ctattgtcat tcctaaagca aatggtattt ccttggctac cttgtcaact ttattgtagc
    38101 ctatatccaa tacccttcca acatctctta ttgcagcttt tgcacccatt gtaccaaaag
    38161 ttattatctg ggctacatgg tcatcaccat attttctctt tacatactct ataacttctt
    38221 ctcttctctc ataacaaaaa tctatatcta tatctggcat ggatatacgt tctggattta
    38281 aaaaacgctc aaataataga gagtacttta ttgggtctat gtcagttatt ttaagtgtat
    38341 atgctactat agaaccagcc gcactacctc tacctggtcc tactataata ttattttctt
    38401 tagaaaaatt tataaaatcc caaacaatta aaaaatactc tacataaccc attttttcaa
    38461 ttacatctaa ttcataattt aatctctcca gtatctcatt gctaggatta tcatatctct
    38521 cttttaatcc attaaaacac aactccctta aataagtttc tggtgtatat ccttctggaa
    38581 catcatactt aggaagatgt atagtattaa aatcaaactc cacattacac atatcagcta
    38641 ttttcacagt attgtcaata gcctctaatg catatggaaa taattcttcc atttcttctc
    38701 ttgattttaa ataaaactca tcactaccaa atctcattct atttgggtca tttaatgttt
    38761 ttcccatttg aatacacata agaacatcat gtattttcga atcttcttta tttacatagt
    38821 gaacatcatt agtagcaact agtggtatac cagtctcttt tgataatttt actaaaccag
    38881 agtttacttc tttttgctca ggtaaattgt gatcttgaat ctccaaaaag aaattttctt
    38941 ctccaaatat gtctctgtag tcaagagcaa attgttttgc tttttcataa tttctattca
    39001 ttaaagcacg tgctacatct cctgcaaggc atgcagaaag tgctataatc cctttgttat
    39061 gctttttaag ttcttccatg tcaactctag gcttatagta aaaaccttct acgtatgaag
    39121 ttgaaactat ttttattaaa tttttatatc cttccatatt cttagctaac agaactaaat
    39181 gtccttgata tttgtcatag tttgggtctt tatctctcaa tccacgtgca gctgtataga
    39241 cttcgcaccc tataattggc tttattcctt cttttatagc tgttttgtag aaatctataa
    39301 caccaaacat acaaccatgg tcagttatag ctattgagct catgtttagt tccttagccc
    39361 tttttataag ttttttcacc ctcgaaaacc catcaagtaa actatactca gtatgtacat
    39421 gaagatgagc aaaatctttg ttcattaaat cacctcctgc tttataattt taattttacc
    39481 acaaatatat gtcctaaaac aaaaacagag acttttatct caaaatagga attaacttca
    39541 acgtatacca ttatatgtta taaattaatg cttattctga gattgtcccc tcaatttatt
    39601 gctatgattt ttttttcaaa tctgttgcaa tttcttctat ttttctaagt ctatgattga
    39661 ctccagattt tcctattggt ggttctaaca tctctccaag ttctttgaga gtcatatcct
    39721 catactcgat tctaatctta gctatctctt gtaaattttc tggcaaactg ctaattccta
    39781 tagtctcttg tatgagctta atattttcta cttgtcttac tgctgcattt actgttttag
    39841 aaaggttagc tgtctcacaa tttactatcc tgtttacatt atttctcatt tcttttacta
    39901 ttttagtatt ttgaagactt aaaagagcgt ggtgtcctcc tataatactc aacaaatctg
    39961 atatttgttc actctctttg atataaacaa cgtgattatt ttttctagcc acaattttac
    40021 tattaaaacc taaagagttt ataagttctt ttagagaatc tgcaaactcc tcattattag
    40081 ttacaaattc catatgatag ttcttttctg ggtcgcttat agaacctcca ccaagaaaag
    40141 ctcctcttat gaaagctctc ttacatcctt catgcttaat taagttctct gaaattttgt
    40201 ttatagtaaa aaatccttct ttatcttcaa gtatacctaa cttttttaat aacatttctg
    40261 aacccatttc gcttgttacc attaatacat aactgttatt tctctttagc atttgattct
    40321 tatttactga gattgtagta ttgatattaa aattcttttt taataattta aatactttac
    40381 gggctattga atttaactct gttgttatct ttagatttag cttcttatat ccaacaattt
    40441 gtatacttcc ccctgattta actagagctg acaattcagc tatattacaa cattcattcc
    40501 cagatataac tcttgctagt tcatttttgg tttcagttga aaaagacata tctatcacct
    40561 attaactaat ttttctttaa cctttttttt atttcttgta aggcaacctt tattatctcc
    40621 ttttcatcat catacctagc taagtctact actctatcta ggtggataaa tttagcatca
    40681 ataaagcctt cctctttttg tggaatagta tccatattct ttgcttgcat caaataccaa
    40741 aaaactgttt tatgaactgc tctattttca tcccagtttt ctttgaatgt atagtgtatt
    40801 tcacctaaat atttcaatat atctgctttt actccagttt cttcacttac ttcacgtaat
    40861 gctgcctctt ggttattttc cccttcttct acttttccct tgggtaacac ccaatctcca
    40921 ttgaacttcc ttagtaaaag aatcgtattg ccaaacagga ctacaccacc agcactaacc
    40981 tcttctctca tcgatgttca ctccttaaaa ctaacataat gataaggatt tctacacaat
    41041 tttttaaaat ccttttttac taacttttgt tgtaattatg atttagggct aactcaataa
    41101 ctatgttaga tatatacttt gcatcatgtc ttatataatt attttttatt tcaattaaat
    41161 tcttctctac agtttttata cccatctctt ttaatttatc tttttgcttt ttatctaaca
    41221 agacttgctc tgctccatct tgtttatata agtcaagcat ttcttctggc aatatctcat
    41281 tatttgcgat tacataatct attaaattct catcagtgtg ttttactata gcattaacat
    41341 gctctaatac attgtaccct tctgtctcac ctggttgagt cattatattt gctatatata
    41401 cttttggagc tacagacgat ttaatagcgt ctacaatacc ctctacaagt aaatttggta
    41461 ttatgcttgt atataagctt ccaggaccca taattataat gtcagcatca taaatagatg
    41521 caataacatc ctttaatggt ttgacatctt ttggatttaa aaaaatttta tcaatagagc
    41581 ttttttgaat ttttgactct tcaggtatac tggattctcc atttattata ttgccatttt
    41641 ctaatttggc aactaaattt acatcttcca aagttactgg taaaactctt cctgttatag
    41701 caaaaatttc acttaattta tatacagctt tttcaaagtt tccatacaac ccattcatag
    41761 cagccaaaaa caaatttcca aaactctgac cttttaaaag cccttctgta aacctatatt
    41821 gcataacttc attcattgtt ggctctatat ttgcaagtgc taataaacag tttcttatgt
    41881 ctcctggtgg gagcattcct aagtcttctc tcaatacacc tgaacctcca ccatcatcag
    41941 caacagttac aattgcagtt atattttgcg tagtgtgttt aagacctctt aaaaataccg
    42001 attgaccagt acctccacct atcacaacca catttggttc tctattttca acaatagacc
    42061 tttgaaatag ttttactttt tcattttttg cttttttata tataaataac gatacaatta
    42121 atgcaatcca acctaaaatt cctacaataa taagtaattt agccatgttt gcctccatta
    42181 tcgcaacata gagtctctat gtttctttac aactctatat cccttattag ataaatcctc
    42241 cgctataaga tttgttatag taactgacct atgtcttcca cctgtgcatc caacaccaat
    42301 tactagatgt tgttttcctt cctctatata ttgaggtact aaaaaatgaa tcatatctaa
    42361 aagtttcaca taaaattctt cactgatttt agaattcata acataatctc taacttcttt
    42421 atcatcacca gttttagctc ttaactcttc aacataatag ggatttggaa gaaatcttac
    42481 atcaaatact aaatctgcat cagcaagtat accatgttta aatccaaaag atactacaga
    42541 aatagttagg tttggattat cttcaccaga agaatatatt ttctttattt cttccttaag
    42601 gtctttaggt ttcatgttag ttgtatcaat tatacatgta gataactcct ttaaaggttc
    42661 cattatcttt ctttccattt ttataccttc tggaatctgc atatcttttg ccaatggatg
    42721 atttcttctt gtcattttat atctctttag caatacatca tcattacaat ccaaatatac
    42781 catttcatat tcataatttt ctttttctaa ataatttaag ctttcatgaa gcgcttcaaa
    42841 aaactttctc cctcttatat ctatccctag agcaacttta tcaatacttg aatttggttg
    42901 ataacataat tctgcaaatt tagttatcaa agcaggaggt agattatcta cacaataaaa
    42961 tcccatatcc tctaaagctc tcattgtctc actttttcca gatcctgaaa gacctgtaac
    43021 tataacaaat ttcattgcta actcctccct tttatcttat gtttattata ttataatgtt
    43081 ttctactaac gatatatcca gattagagtc agatatagtc ttcatagcta gttcaaaatc
    43141 accaactctt tctggacaat gtgcatctga gcctattata aatttatttt ctagcccttt
    43201 tattttattt aattgattta cattcaaaaa agaatggcta ctatttatct caagtctagt
    43261 atttgtcttt tttgctgtct ttgctacttc ttctatatac acatcgcctt tatctcctgg
    43321 atgagtaatt ataaaaatat cattattact tatcgcattt attacagctt ttgtattata
    43381 ttcttttgct ttttcagttt taaaaatata gttattacaa tgatttaata agcttcttaa
    43441 tgatgttgga gtagaaccaa aatgatatcc agccataata taatcaaaat ctctaataaa
    43501 tttatcatcc atatctatat ttcctttatc atctaatatg ttacactcca tacctaaaag
    43561 tatatttata tcagtgtact tatcatttaa ataatctact tcttctctca ttttgagaat
    43621 atcttttttc tttacaccat atgcaatatg tttataacta tggtcagata ttcctattgt
    43681 ttttattcct ttagaaatgg ctacctttac attatcctca atagtccctt tgccatgact
    43741 atataatgta tgtgtatgat aatcagccag tattttcatt tgttaatcct ctccaagtat
    43801 tttgacttct tcttccaaca taaccccaaa cttggcatat acagcacttt ttataacata
    43861 tattaaatcc aaaatatctt tagcacttgc ttctccttga ttgactacaa atccacaatg
    43921 cttctcagat acttgtgctc ctcttaaagt aagacctctc aatccagttt cttctattaa
    43981 tttacctgca aaatatcctg ttggtctctt aaatgtactt cctgcactag caaaatttaa
    44041 tggctgttta gttattcttc tcgtcgctaa atcatccatt aaacttttta tttcatcata
    44101 atttccttct tgtaattcta attctgctga taaagctata tatccgtttt tcgatattat
    44161 actttttcta tacccaaatt ccatctgttc atttgataat tcaaatatat tgccttccat
    44221 atccatcagt cttactgact tcactatatc cttcatttca ccaccatatg ctccagcatt
    44281 catggctaat gctcctccca atgtgccagg tattcctgat gcaaactcaa acccttttaa
    44341 ttcttgcttt tggagagctt tccctaaaac tgataataaa gctcctgact gagcagtcat
    44401 cctagtatca tttatctcat aagaattgaa attatcagct aattctatta ccactcctct
    44461 tattccacca tctttaatta aaatgtttga accatttcca attattaaat acggaataga
    44521 ctcttttttt accaacttaa gtacattttt taattgttct tcagttctag gtctaactaa
    44581 tatatctgct ggtcctccta ccctaaatga aatatgtttt ttcataggtt catcgacttt
    44641 tatatcctct ttacttaata tatttaataa atttatatat atatcttgat tattcattgt
    44701 atttcctccc aaattatact gaactttagc tgtcattatt atttaaatta cattaatata
    44761 tagtattaac tatattcaat aatatatgat tttgcttatc atatggattt tatattttaa
    44821 gcttcttaat tacaaactat attcaataaa tatataataa agtaaaaaaa aaaaaataac
    44881 aacatataaa agaatataaa taatttaaaa aaagcatcaa tatcactgat atcaatgctt
    44941 taaaaggcaa tttaattcgt attatttatc taactatttt tgacatagca aagataataa
    45001 atccctccaa ctactatgga acctccaacg atatttccaa gtgttacaaa taccaaatta
    45061 gttataaatt gaaccatagt tatatttgct cctaatgcca ttcccattgg tataaaaaac
    45121 atgtttgcaa cactatgttg gaatccacat aatacaaata gcattattac tgtccaacat
    45181 gaagccaatt ttgacattat atcttgagat gctgtagcca tccatacagc taaaacgact
    45241 agaatattac aaagtattgc ttttaaaaac attgatgcta tagttgaatt aaccttagct
    45301 tctgccacag ctatagcttt tgtagctgca tctcctgtca atgtagaaga ataaaacaca
    45361 agtgcaacta gcaaaattga acctactaaa tttgcaaaat aaaccagtcc ccagtttctt
    45421 aacatttttc ctaatgttat ttttttgtcc ataagtgcaa tagccattaa agtgtttcca
    45481 gtgaataatt ctgctcctgc cactactaca agcataagac ctactggaaa gaccatagca
    45541 cttaaaaagc tagctacccc tgggtctatc ttgccaaaag tttgactaac tatcatactc
    45601 cccaatgccc caaaacctat aaatgctcct ccaaataaac ctaatagaat tgcattttgt
    45661 gtcgaaatat ttgctttttt aatgcctgca cttatagttg cttgtgcagt ttccccaggt
    45721 gtcaagaatc ctttactcat aaatccttcc cccttaaaaa ttatactttc ccttgtcttt
    45781 ttatggcaat aattatataa taacaatatg atatataata aattttatta acataaaaaa
    45841 tatactatat acttatatat acttgtc
//
LOCUS       DAEQAF010000019        45470 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.020, whole genome shotgun sequence.
ACCESSION   DAEQAF010000019 DAEQAF010000000
VERSION     DAEQAF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45470
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.020"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            76..885
                     /locus_tag="KRN00_001196"
     CDS             76..885
                     /locus_tag="KRN00_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1827063.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
     gene            1030..1269
                     /locus_tag="KRN00_001197"
     CDS             1030..1269
                     /locus_tag="KRN00_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827064.1"
                     /translation="MKCSKCGSVNIEKGILTTGGIYAETIGLKYRGDGKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNTDRNWCKDKK"
     gene            complement(1456..1632)
                     /locus_tag="KRN00_001198"
     CDS             complement(1456..1632)
                     /locus_tag="KRN00_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827065.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1686..1782)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(2137..2811)
                     /locus_tag="KRN00_001199"
     CDS             complement(2137..2811)
                     /locus_tag="KRN00_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1827066.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     gene            complement(3031..3585)
                     /locus_tag="KRN00_001200"
     CDS             complement(3031..3585)
                     /locus_tag="KRN00_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1827067.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            complement(3663..4028)
                     /locus_tag="KRN00_001201"
     CDS             complement(3663..4028)
                     /locus_tag="KRN00_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827068.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            4493..5278
                     /locus_tag="KRN00_001202"
     CDS             4493..5278
                     /locus_tag="KRN00_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1827069.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            complement(5375..6199)
                     /gene="pdaA"
                     /locus_tag="KRN00_001203"
     CDS             complement(5375..6199)
                     /gene="pdaA"
                     /locus_tag="KRN00_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH1827070.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            6420..9539
                     /locus_tag="KRN00_001204"
     CDS             6420..9539
                     /locus_tag="KRN00_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBH1827071.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIHTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANEIELVEDRLVNFVEASFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFIYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINLIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            9557..10156
                     /locus_tag="KRN00_001205"
     CDS             9557..10156
                     /locus_tag="KRN00_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBH1827072.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(10398..12527)
                     /locus_tag="KRN00_001206"
     CDS             complement(10398..12527)
                     /locus_tag="KRN00_001206"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBH1827073.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLVRPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            12793..13041
                     /locus_tag="KRN00_001207"
     CDS             12793..13041
                     /locus_tag="KRN00_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827074.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            13207..14598
                     /locus_tag="KRN00_001208"
     CDS             13207..14598
                     /locus_tag="KRN00_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBH1827075.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            14709..16178
                     /locus_tag="KRN00_001209"
     CDS             14709..16178
                     /locus_tag="KRN00_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH1827076.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNTNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            16243..16836
                     /locus_tag="KRN00_001210"
     CDS             16243..16836
                     /locus_tag="KRN00_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBH1827077.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            17018..18364
                     /locus_tag="KRN00_001211"
     CDS             17018..18364
                     /locus_tag="KRN00_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1827078.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            18546..18917
                     /locus_tag="KRN00_001212"
     CDS             18546..18917
                     /locus_tag="KRN00_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBH1827079.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            18910..19599
                     /locus_tag="KRN00_001213"
     CDS             18910..19599
                     /locus_tag="KRN00_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBH1827080.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            20119..20985
                     /locus_tag="KRN00_001214"
     CDS             20119..20985
                     /locus_tag="KRN00_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1827081.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            21227..22036
                     /locus_tag="KRN00_001215"
     CDS             21227..22036
                     /locus_tag="KRN00_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827082.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            22180..23244
                     /locus_tag="KRN00_001216"
     CDS             22180..23244
                     /locus_tag="KRN00_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBH1827083.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGVIFGGSYKTYYTQNFYK"
     gene            23272..23991
                     /locus_tag="KRN00_001217"
     CDS             23272..23991
                     /locus_tag="KRN00_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1827084.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            24015..24599
                     /locus_tag="KRN00_001218"
     CDS             24015..24599
                     /locus_tag="KRN00_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBH1827085.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIIDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            24601..25950
                     /gene="pabB"
                     /locus_tag="KRN00_001219"
     CDS             24601..25950
                     /gene="pabB"
                     /locus_tag="KRN00_001219"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBH1827086.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDNIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDTHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDVTDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     DDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            25940..26683
                     /locus_tag="KRN00_001220"
     CDS             25940..26683
                     /locus_tag="KRN00_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HBH1827087.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDIPYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEGVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            26717..27418
                     /locus_tag="KRN00_001221"
     CDS             26717..27418
                     /locus_tag="KRN00_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827088.1"
                     /translation="MIGCIYEVYNEEMTKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKILNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            27444..28016
                     /gene="folE"
                     /locus_tag="KRN00_001222"
     CDS             27444..28016
                     /gene="folE"
                     /locus_tag="KRN00_001222"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBH1827089.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            28080..28871
                     /gene="folP"
                     /locus_tag="KRN00_001223"
     CDS             28080..28871
                     /gene="folP"
                     /locus_tag="KRN00_001223"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBH1827090.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGIGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            28882..29247
                     /gene="folB"
                     /locus_tag="KRN00_001224"
     CDS             28882..29247
                     /gene="folB"
                     /locus_tag="KRN00_001224"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBH1827091.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            29240..29746
                     /gene="folK"
                     /locus_tag="KRN00_001225"
     CDS             29240..29746
                     /gene="folK"
                     /locus_tag="KRN00_001225"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBH1827092.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEKLIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            29727..30512
                     /gene="aroF"
                     /locus_tag="KRN00_001226"
     CDS             29727..30512
                     /gene="aroF"
                     /locus_tag="KRN00_001226"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH1827093.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKSQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            30767..32557
                     /locus_tag="KRN00_001227"
     CDS             30767..32557
                     /locus_tag="KRN00_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBH1827094.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            32575..33741
                     /gene="rpoD"
                     /locus_tag="KRN00_001228"
     CDS             32575..33741
                     /gene="rpoD"
                     /locus_tag="KRN00_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBH1827095.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            33906..34595
                     /locus_tag="KRN00_001229"
     CDS             33906..34595
                     /locus_tag="KRN00_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBH1827096.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            34609..35706
                     /locus_tag="KRN00_001230"
     CDS             34609..35706
                     /locus_tag="KRN00_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH1827097.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSIEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKLDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            35769..36341
                     /locus_tag="KRN00_001231"
     CDS             35769..36341
                     /locus_tag="KRN00_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1827098.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(36401..36868)
                     /locus_tag="KRN00_001232"
     CDS             complement(36401..36868)
                     /locus_tag="KRN00_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1827099.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(37254..37730)
                     /locus_tag="KRN00_001233"
     CDS             complement(37254..37730)
                     /locus_tag="KRN00_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBH1827100.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            complement(37850..38941)
                     /locus_tag="KRN00_001234"
     CDS             complement(37850..38941)
                     /locus_tag="KRN00_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBH1827101.1"
                     /translation="MSKIECLFTIFPVLILMYATFYFIPYFVGKKHIYGVSIDQEHKN
                     YNYFIKLDKEFKKLLSLGFIIDFILVFILVFTFNKLELSYFIGIIGFLLYESILYIHT
                     HKKAKKLKSEIYAKLGHIDIDSKLIVDMDFINKKNKIIKKFKIIYLIPILFTLGMSIF
                     IAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCLMVLLYITSIGSIKSR
                     IKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLSIKTKLSTAMNITTLL
                     VIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPSLMVNKRFGIGWTINF
                     GNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            complement(38934..39323)
                     /locus_tag="KRN00_001235"
     CDS             complement(38934..39323)
                     /locus_tag="KRN00_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1827102.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            39515..39961
                     /locus_tag="KRN00_001236"
     CDS             39515..39961
                     /locus_tag="KRN00_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827103.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            40225..40950
                     /locus_tag="KRN00_001237"
     CDS             40225..40950
                     /locus_tag="KRN00_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827104.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            40937..42181
                     /locus_tag="KRN00_001238"
     CDS             40937..42181
                     /locus_tag="KRN00_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1827105.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     LVLETIKINIILVCIIFILIFVLVVRYFKSIYNDLSDMTKYVYYSSEGKPFDMKNKNQ
                     EGQIGLLKTELLKMTTILNEKVELLKREKIFLNNTISDISHQLKTPMTSLIMLNDLLY
                     NDVPYEVKIDFLNKIKNQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAML
                     SMKIPMEIKNQKLTIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKEN
                     PLFSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIY
                     VNSEKGKGTEFHIIFHKMYDSD"
     gene            42261..42938
                     /locus_tag="KRN00_001239"
     CDS             42261..42938
                     /locus_tag="KRN00_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827106.1"
                     /translation="MEILRVENLTKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDRENHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            42939..>45470
                     /locus_tag="KRN00_001240"
     CDS             42939..>45470
                     /locus_tag="KRN00_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827107.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRKNAEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKFKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLLTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTIIELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENI"
BASE COUNT        18446 a         4639 c         7654 g        14731 t
ORIGIN      
        1 ctaatactat agtattatag agtaataatg ttgatttaaa ataaaaataa gatttcggag
       61 gagtttatta tataaatgaa agattactat aaaataggag agatatctaa aatatatgga
      121 ataggtagag attcattaat gtattatgaa gaaataggca ttctaagacc agttagagat
      181 ataaatggat atagaatgta taatatatca gatatatgga aattaaattt aataaaagaa
      241 tttagaagct tgaactttcc aatgaagaaa ataaaagaat acctagatga cagaagtata
      301 gagtctacga aaaatatttt aaatgaagaa ctcgatttaa ttgataaaaa aatagctgaa
      361 tttataagcc ataaggaaaa tattataaaa agattgagtt cgattgaaag tgtaattcaa
      421 aatacaaaaa tagatgagat agaggttgta tatatagaga aaagaaaagc tttagaatta
      481 aatgctgata taaagaggga tgaagacttc gattttttaa ttcaaaaact tcagaaagaa
      541 tatgaagata gatttaatat acttggaaat aacaatattg gttctgcctt ttctactgaa
      601 gcaattaata aaggtatatt taatgagttt aaatctgtat tttgttttct ggaaagtaat
      661 gagaaagtat ataatatagt ttttgatgaa ggatattatg taactttaaa ttatactggg
      721 agtaattcta ataataagat gtatatggag aaggtgttta aatttataga agaaaacaat
      781 tataagataa ttgctgaccc tatagaaatc tacaagatag atatacatga gactggaatt
      841 gtagaggagt ttgtaacgga aattcaagtt cctataacta aatagctata tttcaatgga
      901 ttagatggta aatagaatga aaaaatgttg atttgctacc gatttgccac tgtgttataa
      961 aatcggtagc aaattatatt ttaaattata agatagcatg aaaaaataat tgtttagggg
     1021 gttataaatg tgaaatgttc taaatgtgga agtgtaaata ttgaaaaggg aattttaaca
     1081 actggtggca tatatgctga aactattgga ttaaaatata gaggagatgg aaaattagat
     1141 aaagttataa ataaaacttt tccagtacaa tctactatat attcagattt atgtttagat
     1201 tgtggagaaa tagttagaac ctatataaag gataatactg ataggaattg gtgtaaagat
     1261 aagaaataga ataatttttg aagtatatta atatttgaag ttgaatttta ttaaagatac
     1321 aagtgaaaaa gtataaatgg gaagaaattg ttgtatggaa gaaactttgc atatagggga
     1381 gattagtttt ttaatataat aacattttta aatgtagata aaactaaaaa gggttctcta
     1441 gaaaacaatt tctatttaat tatacttact taccaatacc atcacttgat gtaaacaaga
     1501 ttctactaca ttttctccgt actctagtat aaaatcatct agctgtgtat ctataaaatc
     1561 acaataatca tataaactac taatataagc agttaacatg tgtgtacatt tatccatttc
     1621 atctctaaac atatatatta ctatccccct aaaaaacttt cataaaacaa aaagaacaat
     1681 atctttttgg caactggctg acataactca tagtttattt tataagcgtt agtccctata
     1741 gctttgcgtc actaaatttc tctagttttg ccgatttagt tttattctac aactaaaata
     1801 atacactagg ataagttatt gttcaacata cttgtcagaa aattgaaata tttaacaata
     1861 tcttaacaat atgaaatcta tttttcactc aagaaacaaa ctatatgtat agaatgttta
     1921 ataaaaatta tatttagttt tgtattgaag tttttatatt aaaaagttta gttcacaagg
     1981 gttacttggc tagataatag atgaacaaaa atatcttgaa aaaatatata tgaatggcaa
     2041 aaaacaaggg atgaatttta tatagactca tcccgtaatt atttatatat tgaccttgat
     2101 taaatatatt attattttta agcttcaatt tttatattat atttctaaag tttctataag
     2161 aggattatcg ctaaataatt ttaataaatt tgttttttta tatcctttag gtaacttagt
     2221 atatataact acttctaacc aatccccatc aaggcgttta atattcatgt ttataatttc
     2281 aatattagat tttttaaatt taccttcaat atattctatg gaatcagtgc tgttagaaat
     2341 tttaagagaa acttgctctg ctgtagggag tttcatccat ttcctatctc tatgaagtgt
     2401 tatctgtaca ataacaataa tgatacttga aacaatacca actaagtata atccagagcc
     2461 aatagcaaga cctgtaccgg ctgttgccca tataccagca gctgtagtaa gaccacttac
     2521 tgattgattt ctaataaata ttaatccagc acctaaaaaa cctataccac tgacaacttg
     2581 tgctgcaacg cgggctgggt ctagaccaat acctggagta cccactatat cattaaatcc
     2641 atacttggaa acaatgatta taagtgctga agctaatgcc actataaaat gagtgcgtat
     2701 tccagcttct tttagtctat tctttctctc atatccaatt aaagccccac agaaaccagc
     2761 agtaatgatt cttgctatat attcaaattg aatcaatata tgatggttca tttatctagc
     2821 acccccttct atataatatt atatatacta taatactaca ttttttatgt gaatatagta
     2881 aagtttaaaa tttatataat agttatatat gaatataaaa tgtataaacg tatattatgt
     2941 atataaaaat gatagaaagc atctaatttt aaatgattaa agagcaagct taaataaatc
     3001 aaacttgctc ttttaacata gtgtatgttt ttatttgtga tagttagata aaaatttatc
     3061 tgtgtttttt acatctgcaa aactgttctg tagtgatgcc atgaatactt gatgtacagt
     3121 atttgcatta atttctatat tattccaaga taaattcttc gttgtacatg catcgcttat
     3181 tagagttatg tcgtatcgaa gtttctttgc tgttcttaca cttgtatcaa tacacatatg
     3241 gctcatcatt ccacagatta ctagattagt aatatttttt ttctcaagga tactttgcaa
     3301 atctgtttca aagaaactat ctggtgtgtg tttaattata atttcttcat tatctagtgg
     3361 aaaaacaatt ttatttattt ctgaaccatg agtattagga agaaaaaaag aagctgtttt
     3421 atctgttgat atatgctgta tatgaataac tggtaaattg ttttttctaa aaaacagtag
     3481 tattttttta gcattttcag cagtttcttc tgattgaaat aattcacatt ttccattttt
     3541 aaaataatca ttttgaatat caatcaatat taaagctata gacatgatta tacctcctat
     3601 ttatttttat tataatacta ttgtaaaaaa tgtaaattac ttactttttg gtatgtatag
     3661 gattacttat tgtagcaaat tcctttatta tctagaattt cttgttgacc atgttcaagc
     3721 atatattcga ttcctatttc ttgcattatt tccactgctt ttaacatttt tttaccacga
     3781 ttagtaagaa aatattcaac atgtaatgga tatccagcag aacttatttt atcaataatc
     3841 ccaaaatcac gtaactcttt taattgttga atcaacattt tttgatttat tccataaata
     3901 ttatgttgca attcagaaaa tgttttatta gattgtctta attcaaatat aaggatagtt
     3961 ttccattttc ctttgattat gtcatgtaca atttcaagag gacatgtata ttcagctctt
     4021 attttcatag catatcaccc ccagtaaaat gataataaat tatatcactt gtcttgtgat
     4081 atgacaaata tatatgaact gtatataaat tttatgtttt attaagttct aaatttcttc
     4141 tattgtagtt catatttagt acataaataa ttagtaagat ataagtaaat aaatatataa
     4201 catgactata gaaatttaac tttaaaataa cttatgataa tttagaggag gaatatatat
     4261 gaatatatca agaaaagcta tgaaaataat agaattagca caaaaaattg caaataagag
     4321 ggggatttca gtagaagaag cttggagtga agcagtaaca gaatataaaa ataaatacga
     4381 acatattgca tagatattta aaaatttaga atatttggta gaatataatg attttaaatg
     4441 atactataaa ttataaggta tatcattatt aacatagaag gaggatatct gcttgattgt
     4501 aaaaatagat aatactttag aaaaagaatt ttggcaatat gtatcacatg aagaaagtct
     4561 aaatttattc ataattggat acgttgagaa ttatggattt agctctcaat atcaagatat
     4621 atggtctcag gtagaagatg gaaatataac ctctataata ttaaaaaata agtcaacact
     4681 tataatttat agttttaaaa ataattttaa tataggagaa atgaagaatc atataaaaga
     4741 tttagatgta gaaagcataa gtggaaaaaa atgtgtaata gatagactaa taagtaaata
     4801 caaagatttt tatgaaaaac tagataataa attttgtgta ttaaaagaaa taaaagaaat
     4861 agatttttcc aacatgaagg agtataaaat agaaaatgct caggaaaaag atattgatga
     4921 aataggaaaa cttttaaata ggtcagacta taaagtaagt aaaaattaca tagaagaaag
     4981 aaaagttcat ttaaaagagg gaaatgtaag agcatatttt attagaaatg atgatactat
     5041 gattagcact gtgtcaactg gtatggaaac tagttttttg gcaatggtgg tctctgtaag
     5101 tacagataaa agatataggg gaaaaggact tgcaagttat atggtttaca atttgagtaa
     5161 agaattgttg ttagaaggaa aagttccatg tcttttttat aataatgatg tagcaggtaa
     5221 aatatatcat aatataggat acaaagagat aaatgaatgg acaattcttt ttaaatagct
     5281 ataaaaaata aaaaactcta tcgagaatta aagtatttat aaataactat atttttacta
     5341 taattcatga tagagttttt ttaaatttat gatactattt tttattattt aaataatcaa
     5401 gtgttttaag tttataacct tctttttccc aatgtgtaag aacctcatct aatatctcag
     5461 tatttgttga tgaatttgga tgcagtaaaa ctattgcacc aggatgagtt cttgaataaa
     5521 ttttgttttt ggcaaattca tgagtaggtt gtttcttttc ataccaatct acataagcaa
     5581 aactccaaaa tattgattta tatcctaaat cttgtgtata ttttaaagat tgttcgctaa
     5641 atttacccat tggaggtcta aaatacttag gcatttcttt tccagtaaca tctttgtatg
     5701 ctttttctac acttgtaatt tcttctttga atttttcaaa atctgtaata cctgccattg
     5761 atggatggct ttttgaatga ttacaaacta aatgtccttc tttttccata cgctttatta
     5821 actctggatt gctttttata taactttcaa ctacgaaaaa ttgagcttta gcattgtgtt
     5881 ttttaagcgt atctaataat tttggagtgt ttccactttc atatccagca tcaaatgata
     5941 gatatataac tttttcattg ggatttccta cataataagc tccgtatttt ttaaaaaaat
     6001 cagcttcttt tataggtgat ggctgtttac catcctccct agggttaaaa taccaatcat
     6061 attcatgtgt gtcgagtgtt ggactagaaa tttgagtttt tgttttatct aatgatttaa
     6121 aatttatact agcaattcca aaaagtatta gagcaaatgc tcctatcata atgtattttt
     6181 ttaggctatc ttttttcaca atttcacctc ttatttaaaa tttaaagtat atttcttata
     6241 atatagtttg aatatttata gttaaaaata ttcacatata caaataataa atgaaagaag
     6301 tttactgtaa gatataaagt tgatattaat tatcttaaat aaagtgtata taaatgataa
     6361 aatataaaga gaaatgattg taaataagtt aggctggttt aacttgaagg gatataaaaa
     6421 tggataatat aataagtgta ttgaatgatg ttgttttttt agatatagaa gttagtggat
     6481 tagattgttt aaattcagaa attttagaag ttggagctgt caaggttaaa gactggaaaa
     6541 tacataccta tgaatcatta ataaaaaaca aatttgaggt acctatagaa gtattctcag
     6601 tatgtaaaaa tttagataaa aatgatttag aaatagctaa tgaaatagaa ctggtggaag
     6661 atagacttgt aaattttgta gaagctagtt tcattatatg tcatgattta agtctgaaaa
     6721 aaaagttttt tgagtatcat atgccaaagt taaaaaacaa atttattgat ttaattgaat
     6781 tagcagttat tttagaacca tatcataaag attatagctt agaatactta aaaaatactt
     6841 taacaaattg taattctaaa gtggaaaata gagctttatc agatgctatt gatataataa
     6901 atattgtaaa ttgcctttta gtaaaattta ataactatga aaaaactact ttggagccat
     6961 tgagttttaa aataaattca tatcttaaaa aatttaatct tccaacatgg gaatggagca
     7021 aatttttaga agaggcaaat tatgatttat caaataatat aaatataaaa aaagaatata
     7081 atatatttga ctcaaaagaa gaaaagaaga aggaaagaga aaccttaaaa attttaaatg
     7141 aagaagaaaa aaattatgaa gaattattaa aatacaaaac tatttgggag aataaagaag
     7201 gatttatata tgaatataga cctggtcaat atgagcttac taaaacaata agagagttgt
     7261 ttagaaatag cgaagatgaa gaaaaaattg catgtataga ggcaccaact ggtataggta
     7321 aaagtgtagg atatttattg cctgcaatat tagaggctag aattaataaa aaaagattat
     7381 taatttctac tgacacaaag gaattgcaga tacaattaat aaataaagat attccaaatg
     7441 tgttagattc tttaggtcta aatggaaaag taagttacgg atatataaag ggaaaaaata
     7501 actatatttg tatagataga ctggaagcat atatagatga ttatgagtct caaaacccta
     7561 ctaaaggaga aattttatct ttaatatttt tgaagagatt agttgaaggt ggcaagtatg
     7621 gagatataga agaaataaat tatttagtgt ttgacaactt caaggaaata agtactcact
     7681 taagaaatgt aagttgtgac ccaaatatgt gcagacctaa aaaatgcaaa aaagattgtt
     7741 tatataaaaa cagaatagaa gaattaaaag aagaacatat aacagtagta aatcattcac
     7801 tattagctaa atggccatat aaggatgaaa aacctttaga aaatataata gtagatgaag
     7861 cacataattt gactgaaaaa ggatatgatt tcttttcaag cattataaat tcaaagtctt
     7921 taaggtattt attacaagaa atttatcctt acgagtttat tcaaaatagt agctttatat
     7981 ataaaaaata tagtagaaat atgagaaaaa taaaggcttt tgataaattt tataatgtat
     8041 taaaaattgg aagagaagat aaacaaaaaa ttgctagaag tataaatctc attattgaag
     8101 agatagattc aatattaaag tttggtaatt gtaatgaata taataatgta agtaattata
     8161 atttaagatg ggaactgaat ttgcaaatag acgaaattgt gggaaaacta aaaaaggatg
     8221 gtatagatac tgaaataagt tatagagcct atagtgaaaa gataaagttg agttgtgaga
     8281 aaataataaa aaatttagtt tcaataataa taataattta taggaatatt gatgatgata
     8341 gtatagataa agaagcagat atatataaat ttggaaaggc aaagacaaga gatttagagg
     8401 atataaagat tatatttgaa atctttttag agtatgatga aaaggatgat tatgcaagga
     8461 tagttgaaat tgataagaat tataatgact ttgaatttcg agtagtgcca ttaaaaatag
     8521 cagatttatt tgaagaaaat attttatctc aattagaaaa aggaatattt ttatcagcaa
     8581 ctttgagttt atctgaaagt atgtcttatt ttaaaaatac attaggaata gacagagtta
     8641 agaatgtgga aaagattata gaaccaattt ttgattataa aaatagagtc tctgtagttg
     8701 gattttctga tatttgtgag tacagaaatt ctgaatttcc aaatgagatg agtaaaatta
     8761 tatctaatat atcaaagatt acagaaggtc atacattagc tctttttaat agtaaagata
     8821 gacaagaaaa aacttatgaa atattgaaaa aatacttaca tagttttaac ttagaaattt
     8881 atgctgataa aaagggcatt agacacctta atgatttaaa tagaaaatgt gtagtacttg
     8941 gctcaaaagg atgttttgaa ggcgtagaca ttccagggga tggtttggtt tgtgtaactt
     9001 tagacaagct tccgaatcta aatccaaaag accctttgta ttttactata atgaagaagt
     9061 atggtataga ctactatact ataaattatc ctcaaatgac cataaaggta aagcaagcta
     9121 tggggagaat tttaagaagc aaatatgact atggatgttt tgtgattttt gatgtaggaa
     9181 ctaatataag tgttttaaag agattagaga aagatttaca cgattgtaaa atttcaaagg
     9241 ttaatagcaa tgagttttat acttatataa ggcgacattt aaataaatct agaagtttaa
     9301 tactaaaatc tgttatattt gatactataa aagcgttgaa tgttgatgct aaaatggata
     9361 acaatgatgt tgataaggat attataaaaa aagatataaa tgaaaatata agacaaagag
     9421 ctgtaaaagg agaagtgtac catattgata ttataaaaaa agatatgaaa gtaaaatatt
     9481 ttgatagaaa ctatcttata aatttagata tatttatgag agaagaagat aaaaattaag
     9541 agtgggagtg agatatttgg caaaacaaaa gttttatgct gtgaaaaaag gtaaaaatat
     9601 aggtgtatat aatacatggg atgagtgcaa aaaacaagta aatggattct caggagctga
     9661 atataagagt ttttctactt ttcaagaagc taaagaatat attgatgggt cagaaaaatt
     9721 gagttttcaa gaagataagg agtttataga agcatatgta gatggaagtt atgaacattc
     9781 agtaaaaatg tatggttcgg gtgttgtgat tttaaaaaat aatgaagtta taaaaactta
     9841 tagtgaaaaa ggaaaagaga aaactttagt aagtatgaga aatgtagctg gagagataga
     9901 ggcttctaaa attgcaatgc agtactgtat tgacaataat gttcaaaact tgattttata
     9961 ctttgactat gaagggattg aaaagtggtg tactggagtt tggaaaacaa ataaagaagg
    10021 aactatagca tataaaaatt tctatgacag tattaagaat aagcttaatg taaaatttac
    10081 aaaggttaaa gctcattctg gaaataagta taatgaggaa gctgataaat tagctaaaaa
    10141 agctattggt gtataataaa aaaatattta tacataatta catggtataa gagtatatct
    10201 aaattcctac tttatgatta aacaacttgt aattaaacaa cttataatta aataaatttt
    10261 gattaaaaaa gcagattgta ttatgaaaaa ataagtatct aatttataaa caattaataa
    10321 tagtattaat tagatacaac ttatttaata taataaaatc tgctttttat ataactataa
    10381 aattttccta cattctatta gaattgccca taaatacctt caagttcttc ttttaatact
    10441 tcagggtcat ttataccaat agacatggtt ctagccagta tatttgcttg gtcataagtt
    10501 gatgtccatg agaatacacc acctagacaa tttctaagaa catattgagt ttttaagaat
    10561 attgataaag catcatcata tgacattgca aaatctccat ccttaactaa atacggaact
    10621 tgagcagtat tatcaaatct atattcatat ccatttttat ttatataatc ccttctaagc
    10681 tcatcataag ttcttgttat agtagcacct aatcttccat aaaatggtat accgagaagg
    10741 attttttcag aaggcattcc agcattctca agatttctca ccattgcatc aacactatat
    10801 cctggcaaag ataagtctga atcaaaaaga tttgcttgat gttttctacc atttgggcct
    10861 gtttcacctg ctgtaaaatc ataactcata agattaaaat aatctattat aggagctatt
    10921 ttatctattt cagcacttga atttatatat cctctatctc ctgttccagc tacactaagc
    10981 catttatcat ctcctataac atctcttatg gcagttagta agagtgtaaa gttttctcta
    11041 tcttgaggtc ttgatgttat tccagatgca ctacttccag gatattccca gtctatatct
    11101 attccatcta aagcatattc atttatcatc tgattgacct gtcttgcaaa attatatcta
    11161 gatgtaggtg ttaatgctgc atcagagaat ccttcagctc cccaacctcc aatagctaca
    11221 attactttta agctaggttt ttcaccttta agagcaagta attgatttaa aaatctagga
    11281 taaggaataa acaaatttcc agactggtct atctcagcaa aagcaaatat aactgcatct
    11341 aatagttgag catctacatt agttggattt ccaagaacat attctgctac aattggattt
    11401 atatctggac agtttgcatt ttcaactatt ggattgtatg ggtctgttat ttgtggtcta
    11461 actaattttt ttgaatcttt taaagttttc atagctattt ttttagtatt tttttcgcta
    11521 gtataatcgt agtttttata attatgttta tagaaatctt cataactact atcttctttg
    11581 ttatagctag aatttatttt gtcgcaagat tcatctttat catagttaaa attcatttca
    11641 tcacaagact tatctttaaa cttatcttgt ttggagttgt gaactttgtt agtattttta
    11701 gtatgttttt tctcatggtt gcaatcatct ttaatatcag tcttgtgttc ttgtttacag
    11761 tcaagagctt tgttcaggta gtcatgatgt tcatgttcac agttacattc attttcaatg
    11821 tttttagtat gttctttttt ccagctacaa gtattatcaa ttttcttgct cacttcttca
    11881 tcattataat tatctggtac aaaacataag taccagtcca tacatgaata tttcttatta
    11941 caactgttaa ctctattttt taattcctta tagtttttag gataaggtaa aatcactggc
    12001 attccaggaa accagtttgc aggagtaact atattatctc tatcactagt ctgaagtgca
    12061 tctactattc taagtatttc tggaatattt cttcctgtag ttagtggata ataaagaatc
    12121 gttcttagaa tttgattatt atctataata aatacagagc gaacagttga tgtatcactc
    12181 attggttttg atatcatgcc gtataacttg gcaattctca tatctctatc ttctataata
    12241 ggaaatggaa tttctacacc tgtaagtaaa gaaatattat acatccaagc taaatgtgaa
    12301 ctgttactat caacacttag accaattagt tctgtatttc tttttttaaa ttcgtcataa
    12361 tatttagcaa aacataaaaa ttctgtagta caaactggtg taaaatcacc aggatgtgaa
    12421 aataaaacaa tccaattacc cttatagtca gagagtctaa taggaccatt tgttgtattg
    12481 gctttaaaat caggagcctt tgaccctaaa cttggcaaat ttggcatgta aatcacccct
    12541 caataaatta tcatttattt tattctatta attaatacat attagtgtta ctattttatt
    12601 aaaagttaag taatccttat gtcaaaaaaa gatatttatt aaaaagattt aatattttcc
    12661 taatataaat gacaatagta attgctattt ttttactaat ttggtatagt aatggataag
    12721 gggtagtgtc aattttagtg attatacgag gtgagtggat tgaaaaaaat tctaagaatt
    12781 ttagttatct ccatgatgat atgttttgca atgacttttg cattagtgtt aataaattca
    12841 gttatgggag tacatatagg attggattat tactttttga tgggaagtgt gcttacagtt
    12901 tgtttaacaa ttggaattgt tttatgcaat gctagaaaaa tatttgatag caaagctata
    12961 cacaagacaa gaacgaaaac tgtcagtaat aataaaaaac aaaagagtca ttctagggat
    13021 ataaaaagaa agatatcata atttatgtaa aggaaatatt tatgtataaa ataatgattg
    13081 ataggtaaaa taaaaacacg atttaacttg tgtttttatt ttttttcaag aattatgata
    13141 taataaccaa taagaaattt agtttaccat aaaatataaa gattattaaa tggagaggga
    13201 actataatga attttagaga tttatttgag aaggctgtag attttattga tgaaaaaagg
    13261 aaatctatag ttgcgatttc attatcaaca ttaggtgtaa ttgctttgat aatagtattt
    13321 ttcttaagta gtaacgagtt tagtgtagga aatgaagcta atgagttgtt aaagattata
    13381 gagaaaagac agtattctat agctgttgat tactacacaa gtatagaaaa aaagttttct
    13441 gattcaaaaa tggaaaggtt taataagtct gtttctaaaa aaataaataa attgctatta
    13501 aatagtggtg ataaatattt agatggagac ataagtcaag aaagttttat tggattaata
    13561 aataccgtga aagaattaaa caaaataagt atagatgtgg atgacttatt agctcaagct
    13621 gatagagtta gagaaatgta taaagaagaa aatactactt atgatattgc cattaactac
    13681 ataagtactg tttcaatatt aaatggaatg ggtagtaacc tagatgtata caaacagaat
    13741 atagaaacaa tcaaagagtc tagagatgtt tatgactcag cagtaaaaga ccaaaaagca
    13801 tataagtatt atgaagctat tgaaaagtat aataaagtat taaaagaaga tgaaaagtat
    13861 tacagtatgg ctcaaaatgg gaaagaacaa tgtattgaag aaatgtatga ttactatata
    13921 agtagagctg aagaggcaaa tacttctgga gattatgaaa gagcattaca atatattgag
    13981 tatttaaaag acgattattc agatgatgaa aaggtacaga gtttagaaaa aaaatataaa
    14041 aagaatttat cattgtatac tttaacatct gatgacatta taaatgtaat agctaaaaaa
    14101 agtggcaaag acaaggcaaa tctatctata aattcacttc cacaaatgat aaaaaataat
    14161 aaatactatt atgctgaagt atatgagtat gataaattaa taaatgaagt tttggtaagt
    14221 gcaaaaacta aagatttata ttcatataaa gatggtaaaa aagattacaa agtagattat
    14281 ggtgatggat actttagaat attagaagat ggaagttatc aatttggtat tacaaaagat
    14341 aaagctaagt ttgtgttaac taatactctt gatgaaaaag aaaataagta taaaaagatt
    14401 gagatattag atatagagaa agcagataga tatgtaaaaa gtaaaaagag tttagaagaa
    14461 ttgtttggaa aatataaaaa tatttattat tatgctgtag taaataaagg cttatttaga
    14521 ggcaaagaag tttatgctat taatatttac aatgaaaaaa tatatgccat atcagaaaat
    14581 ggactaaatg aatattaata atattaaatt aatatataat taaaaagttt ttggggtttt
    14641 aaggcgcatt atgtagtaat ataataatag ggatatataa ataattttat tgtaaggaga
    14701 agtatgggat gagtaatgtg aacaaaaagc tagttatagc tattggagct gtagcattag
    14761 tggtaataat ttttataggc ataatgtgca tgcaatttaa aggggagaaa atagcaaaaa
    14821 acacatatgt taatggagta aatattggaa aattaactaa atcgcaagca aaacaggaat
    14881 tagctaaaaa atacaaatta gagaatgttg attttaatta caatgataaa agttggaaag
    14941 taaagagcaa agatttaaat ttatctactg acctggataa aacagtagaa aacgcatata
    15001 atttaaatag aaagagtgct ttctttggca atctatcaaa aactatttca gcaaattttg
    15061 gcaaaaaaag caacttagta gttgcgataa attatgataa aaataaatta aaagcagaaa
    15121 tggaaaagat agctaaagaa atagatgtag atgtaaaaga tgctacactt gatataagtg
    15181 gtgaaaaagt caaggttata ccagattctg atggtcttaa aatggatatt tctaagagta
    15241 tggagaattt tgataatcaa actaaaaaag gtaactataa aaatgagtta gtagtaaaag
    15301 ctactccagc aaaagtaaaa aaagagcaac ttgctaatat agatacaaat ttaggtacgt
    15361 attcaacaac atttaaaact tctcaaataa atagaagtat aaacataaaa ttagcaacag
    15421 ataatataag taatgtatta cttatgccag gagaaacttt ctcatttaat aaacatacag
    15481 ggaaaagaag taaggaaaat ggatataaaa gtgcacctgt aataatggaa ggtgagatgg
    15541 aagaagatta tggtggagga gtttgtcaag tttcatctac gttatacaat tctgtgctat
    15601 acgcaggttt agaaattgtt aatgtaaaaa atcatactat accatcaagt tatgttccaa
    15661 aaggaagaga tgcaactgtt gcagatagtg gaatagattt cttatttaaa aataatctaa
    15721 agcatccagt ttacataaaa aattacgttt caggaaatca aattgtttgc aatatatatg
    15781 gaagtgcaga agataaacaa aatataacaa tatcaacaaa attagatggc gtttcacaaa
    15841 ctacaatgaa aagagttaat gaccctacaa tgcctaaagg taaagaaaaa gtagacaaaa
    15901 gtggaagaaa tgcatattct gtatcaacat atagaacatt taatgatgca aatggtaaaa
    15961 aaattaaaac tgaaaaaata gctaattcat attatcctaa gaaggaaggt attatattag
    16021 ttgggactat ggaaccaaaa ccagaggaaa aaccaaatac agacgaaaat aagaataatc
    16081 aaaatacaaa caatcaaaat ccaaataatc aacaaaaacc agaaacacca ccaactgata
    16141 ataagcctaa tgagacacaa ccacaaccgc aagcttaaag ttctcaagaa taggatttat
    16201 gtagagtaat aaaaaatata aatctaaata ggagggatta ctttgaattt aaataatata
    16261 acgaattacg ttcaaagtat ttgcgagaat atttctaatg tcttggatgt agatgttact
    16321 ttagttacaa aagatttaac taggatagca ggtacaggaa tattcagagg taaaatagga
    16381 gagacaatat cagagaagtc agtgtactct cttgttttaa aagatggaaa atcctatgtt
    16441 ataaataaag aaatagaaga gaactgtaat aaatgtgcaa atagagaaaa ttgtaaagag
    16501 ttagctgata tatgtactcc cgttaaaatg ggagagcata tacttggaat cttgggtata
    16561 gctgcgttta atgaagaaca aaaagaaaag atactttcaa aagataagga gttaactgct
    16621 tttgtaagga gtatgtctga tttaatatct tttaaactag atgaacttta taaacaagaa
    16681 gttaagacta tagatgacct tgagagggaa gctatagaaa atgccataaa gaaatatgga
    16741 agtaatacag aaggtatgaa aaaagtagct gaggcattaa atataggtat agctacactc
    16801 tatagaaaag taaaaaaatt caacattaaa agttaatagt attgaaaaag aggtaacctt
    16861 tttatgaaaa gaagaggatt acctttttta ttatgagaat ggtggaaaaa tatgtatagt
    16921 tttgacttga catattaaat atgttatctt aaatatatat tttagagtgg aggtgagtat
    16981 tattttagtt aaagatataa aacaagacat agaaagcatg cctagaaaaa ttttagatat
    17041 atctttgata gaagataata aaagtgattt gacttttttt aatatagaag aagaagacgg
    17101 tgatgaaaca ttaaaagcat taaaacagag ttatgtgact acaaattata aagaagaaac
    17161 tctattaaac ttgcaagggg ctttaaattc aaagtcagat acaacgtcta aggagttaaa
    17221 attagaatca tataaaagat ataacaatgc attggattta gcatataaaa attatataac
    17281 tagtgccatt aatatggtta ataaagctct ggagataaat cctaaagaca ttgatatact
    17341 aaatcttaga ggtcttttaa aattattaaa atgtgatttt gctaaatcat ttgagagttt
    17401 ttatactgct ttatgttatg aaaataatca tatatctaga aaatatgtaa atctaatttc
    17461 atctgaagat tttaaaactt ttttaggaag atacaatcat tctataagat ttataaatga
    17521 agaattaaat tatgagtcaa tacatatttt agagaacata attgaagaag aacctgaact
    17581 aatagagcca tatgtaattt tatctttgtt atatgataaa ctaggtaatg taaaaaagag
    17641 agaaggatat ttagacaaac ttaaagagct agataaagat aatcctgtat ttgaaaaaaa
    17701 tgaagaagaa aaagaagata caagtaaaaa ggaagaaata aaaaaagtaa aaagaaagaa
    17761 aagtattttg ccatatatta tagttggctg tgttttaata ggtatgggga tatatttgat
    17821 tcaaagcaaa aagagaatag aaaacttgaa taaccaaata agtagtaaag aggaaaagtt
    17881 aagtgaaact gataaaaagt taggagaaac gagtaaaaaa ttagaaaaaa cgaataagga
    17941 attaaatgag gttaaaaata aagaaccaga aagagagata actgtagctg atgaggaaga
    18001 tttatattat caagctctaa atttaaagaa aaacaaagaa tatgaaaaag ccatagataa
    18061 ttttaaaagt gtagtttctt ctggtaaaac taaaaaatat atttctgagt caatatatca
    18121 attagcaata acaaataaat tattaggaaa taaggatgaa gctataaaat attacaaaaa
    18181 atatataaat acttatacta aaaatgacca gtattatgat gattcatatt acgagttggg
    18241 tatgctttat tatgataatg gcgatttaaa aaatgcacaa cagacttttt atagtttgag
    18301 aagtgaagtt ccagacagta tgtataacaa ttcaaaaata aaagaaattt taagtgaaaa
    18361 ataggtttat atagttaagt tttttgaaac aaccaagtat gtattttatt aaattaaaat
    18421 aaaaataaat ttaaaaagag attgtgtcaa attataactt tctattttaa agaaagatat
    18481 ttgcttgttg ataaaactac aaatatatga tttgaagcaa tctctttaat ttttggaggt
    18541 ggaaaatgaa agttttcaat caattagtaa taattttatc tatctgggta ataggagagt
    18601 atataagttc ctttatacaa ggaattatac ttattcctgg gagtatagtt ggtatgctat
    18661 tattatttct actactacaa tttaaagttt tagacttgag tagtatagaa aatgtaagtg
    18721 gatttttcct cgataatatg gctatatttt ttattccagc aggtgtatca cttataaagt
    18781 cattagacct aataagggaa aatgtattag tgcttttatt agtcatatgt ttaagtacac
    18841 taatagtaat gtatactact ggaattattg tggagaaaat gataaaaaag aaggaagaag
    18901 gacaaaaaaa tgtataatgt attacagaca ccagtatttg gtataatagt aacaatagtt
    18961 tttttcaatt taggaagata cattcaacga aaaacaagta atcctatatg taacccttta
    19021 ttaattgcaa tcgtaggaat aatattgttt ttaagcatat ctaaaatccc ttatgagaat
    19081 tacaagatag gagctgatag tctaaatttc tttttaggtc ctgtcacagt agtacttgca
    19141 gttccacttt ataaacaatt tgaattattt aaaaagcata tgtttgagat tattgtagga
    19201 ataggttgtg gtatagtgat ttcttttgta tctgtattga taattggcaa aatagctaat
    19261 tcagatgtaa gtataataaa ttcactaatt ccaaaatcta taacaacacc aatgggaata
    19321 tctttagcaa attctttaaa tggtatagaa tcaataacag ttgtagccat aatttttaca
    19381 ggtatttttg gtggtatggt tgcttctaca gtattcaaac tggggaatat aaatcatcca
    19441 gttgctaaag gaattgctct tggaacatct gcacatgctt taggaactac aaaggctttt
    19501 gaacttggag aaatagaagg agctatgagt ggtgtttcta ttggagtctc tggtacaatt
    19561 acagtaatac taattccaat tataatgaat tttatataaa aaataaaatt aagacgagta
    19621 ccttgaatac ttaaaacaaa ataaaataaa aaaaatttaa aataaaaact gaacgaaaaa
    19681 aatgcaaata atgaaataaa aaaatcatgt actgaaatta taaaaagaaa aatttcattt
    19741 aggaattaat tataaagaga caattactaa acttgaattt gctaaaataa aataaattac
    19801 tgcgaaaata gatatttaga aaaaaatact ataaatttac tatattgcaa gttaaataat
    19861 aagcagtatc atattatgct agaaaaagtt tcatttaagg cataaatgag atgatttgaa
    19921 cgtttttaaa gattagaata taaaagattg cactagacat atatgaaaaa gataatataa
    19981 tagatgatgt aatagatgac agttcaagaa attataaaaa aaatttattt gaaatattat
    20041 ctattacatc aggaataata tatgtaagag taagctttta aaattctaaa gatttagaaa
    20101 gattgaaggg agaaagaaat gagtgaagtt aagaataccc tacaaaaaca tccagtttta
    20161 agatattcaa caatgctatt tgggatgttg atgacatcta taggaataaa tgggttctta
    20221 agaccagcac atctgcttag tggaggtgct acaggtatag caacatctat aaactatttg
    20281 acaaatataa atgtaggttt attaacattt ttaatcaata ttccaatatt tatcttaggg
    20341 ttcatatacc ttgaaaaaga gttttgtatt tcaagtttgg taaatatgat tgtattttca
    20401 ttattattag gagcaactca ggaaataagt aatattatac ctatacatga tatattgctt
    20461 caaagtgtat atggtggtat attatctggt ttaggagtcg gagttgtatt tagaactagg
    20521 tcttctcaag gtggtacaga tataatagct gcaatactaa aaattaagaa gaatatagaa
    20581 atgaaagaca ctgctttagc aataaatggc ttgatagtac ttacaggaag ttttttattt
    20641 gggttggatt tagcattata cactcttata ggtctatttc taaatgcgta ttcaatgagt
    20701 tttattaaag atgcaatgaa ttaccaaaaa tctgttatgg taatgtcaaa tgaagtcgat
    20761 ttaatagcag aagatataat gaagagttta gttagaggtg taactttttt agatgcagaa
    20821 ggtgcataca ctcatcaaaa aaagaagatt atatatacaa tagtttcatc aaatgagata
    20881 ccaaagataa aagatatagc tttgaagtat gataaaaagg cctttatatc tgtaaatgat
    20941 gttacagaag taaaaggaag agggtttaaa gcaaaagatt tatagaaaat tttacaagct
    21001 gggagtttat aatgtaaatt tgtatattat atctctcagc ttatttaaat ttagtatacg
    21061 aaaataaagg ttttattaat gatttgtgta tcactttaaa agatatcatt ttaaaattaa
    21121 aattgaaaaa attacttaat atgtagaaaa catgaccact attaggatat aataaattta
    21181 atagatttag taaaatatct aggaataacg ttggaggaat ggcattatga atttatctaa
    21241 agaatatgtt aatttgtatg ataattattt gaaatatata aatgaagtaa acaaagagat
    21301 tagaagtata aagaacatga agaaacgtgt tttaaaaagg ggcgattttg ctccagaaaa
    21361 tgaagtatta gaattggaag gaaaaacaat acgcgatata gatgatgtcg atacaaaaaa
    21421 accaaaaaat aaaatctata aattttcaaa tggggatgta tatgtaggga aattcttaga
    21481 gggaaagatg gaggggaaag gctcatatac tttttttgta gatgaaggaa cagttatgga
    21541 gtacatagga gaatttaaag aagataaaaa aaatggaaaa ggaaacttta tattttcaaa
    21601 tggaaatgaa tatataggtt attttgagga agatatgatg agcggtattg gaaatatgtt
    21661 atatagtagt aaagatgaat atattggaac ttggaaaaac ggaaaaaaag atggaaaagg
    21721 tatttataag tggagtgatg gatgtatata tgcaggtgaa tttaaaggtg gaaagatgga
    21781 agggtacggt atttgctata atagtaaagg ggaagtactt tatgaaggag aatggaagaa
    21841 taatttgatt catggtaagg gaacttatat atgggaaaaa ggtaaaaagt atataggtga
    21901 atttatgcat ggtaaaaaac atgggcaagg aactttttat ctaaataatg aattggttta
    21961 tgaagggact tggaaatttg ataagccatc tatatttgat agaacattag atgaaatatt
    22021 ttccttgaga ctgtagcttt atctaattag tagataaagc ttttttctaa tacttactgt
    22081 aaataggtat gaatgatatt gattagtata cactatcaat attaacttaa taaatgcaat
    22141 attaaaaaat tttgattgat tttaagaagg agagatatat tgaagagatt aattgcttta
    22201 gtgttagtag tacttattgt tttattttat agtcctgaat tattaaaaga aggatatgat
    22261 ttaaaagaaa agttttttca aagtgaaata tggaatgaat ttttagacaa aataaatata
    22321 aatgataatt ctaagaaaga taaaaaagaa aaaagtcaaa atttacaatc aaataatact
    22381 gaaggggaga acttaggaga gtcagatata aagaattttg aaaaaataag cttaggagat
    22441 aatttaagct atgttttatc aagtatcggc aaacctggta gaattgatat tagtgaatat
    22501 ggttttgatt ggtatgtata taatcaatat ggaaaagaat ttgcaatggt tggacttgaa
    22561 aatgatgaag tagtagcact ttatagtaat tctattaatt catgtgaaaa tcaagatata
    22621 aaactaaatc aagatagaca aacagtgaga actaagatta caccattaaa atataagaga
    22681 aaaggaaata ccagatatat aataaactca gaaaatcaat atgatataat aagtaaggaa
    22741 ggtaagtata ttacaatttt ctacgatatt catgaagaaa atagagtttg ttcatactta
    22801 ataattgata aaagcactga agatgagttt aaaaatttat atccagatga tagcgaagaa
    22861 cttaaaaaat gttttgaact tgaagttata gaccttgtaa atagtgttag aaatcaaaga
    22921 gggttaaact cattgagata cagtgaacag gcaactttga gttcaagaaa acatagtgaa
    22981 gatatgagag ataataattt ttttgaccat gtaaataaga agaatgaaac tccatttgac
    23041 agaatgaaaa gagaaggtat agtatatact tcagctggag aaaacatagc agcaggacag
    23101 attaatgcaa tatatgcgca tgaagcttgg atgaactctg aaggacatag aaaaaatatt
    23161 ttggggaact ataataatat tggagttgga gtaatatttg gaggaagcta taaaacatat
    23221 tacactcaaa atttttataa ataactaaaa tatttgaaag gaagttaaaa aatgacatca
    23281 tggaaaaaaa agacggtata taagtgctta atagcagtag tcttgttttg tggaatagtg
    23341 ttaatatcta attttagtaa agtttctgct ttgatgatgg atactaatgg aaatgttttg
    23401 attaaacatg gttcaaggga aaaaaagcta atagcaatta cctttgatga tggtcctcat
    23461 cctaaagaaa ctagtcaagt tttagatgta ttaaagaaat acaatgtaaa agctactttt
    23521 tttatagctg gaaaacatgc aaaatggtat aaagaaccat tagtaagagc aagtaaagaa
    23581 ggtcacgaga taggaaatca tactttcaat catcctgata taagtaattt aagttctagt
    23641 cagatagaag aggagattgt taagtgtgaa gacattttga aagaagtaac tggaaaaaaa
    23701 ccgacattat ttagaccacc atttggaagt tatagagaaa aagaattaat agaaattgca
    23761 aaaaagcatg actataaagt tgttttatgg acaggtgtag atgtgaaaga ttggaaaaat
    23821 ccaggagcta atagcattgc agataaaata attaataaag tacaaaatgg agatataata
    23881 cttttgcatg attatgcaac taatgataca gttgaagctt tagatatgtt tattccaaaa
    23941 atgattgaaa aaggttttaa atttgtaaca gtttctgagt tgataaaata atttttaggg
    24001 gggagattta cagtatgatt cttatgatag acaattatga ttcttttgta tacaacctag
    24061 tccaatatat agaagaatta ggagaaacag ttgtagtaaa aagaaataat gaaatcaaaa
    24121 taagtgacat tgaagaacta aatccagagg taattgtgtt atctccagga ccgtgttctc
    24181 caaaagaagc tggtatttgc atagatattg ttgagcattt taaggggaaa aaacctatac
    24241 taggaatttg tttaggtcac caaactattg gacatgtttt tggaggagat attataaaag
    24301 cacaacagcc tgtgcatgga aaagtatata gtatcaacca tactaataaa ggagttttta
    24361 ggggacttaa aaatccttta aatgtcacta ggtatcattc actaataatt gattccaata
    24421 cagttccaaa agaattagaa attacagcaa ttactgataa aggggaaata atggggatta
    24481 ggcataagaa atatttaata gaaggagtac agtttcatcc agaagctatt ttgtcagagt
    24541 atggtcatga aatgcttaaa aattttataa cagaagctag agaaagggta catatgtaat
    24601 atgataagag agataaatac taaattaaat tcttttgaga tatttactat ttttagaaat
    24661 gaacatgaca gttttatatt agacagtgct atggataaag aaaaattggg aagatattct
    24721 tttataagta gccaaccatt taaggtatta aagtataaag atactgatga aaatccttta
    24781 gaagttttaa aagaagaact acataagtat agggttgtaa atgatactaa tcttccattt
    24841 gtaggaggtg ctgtgggata tttatcttat gatttaggta attacataga aaatttacct
    24901 agaactgctg tagatgatat tgagatgcct gatatgtatt ttggatttta taatcatgta
    24961 atagttatag accatcttgt gcaaaaaact tatatagcta ctccaaacat agatatcgaa
    25021 ttagaagaaa agataataga taatatagaa caaagaatat taaaagaaga gaaaaaaggt
    25081 atagatagca tatgttatga agaaaaagaa gtaacaccta taagacttaa atctaatttt
    25141 acaaaggaag aatttaaaaa tgcagttcaa agtgttagag agtacataag acaaggagat
    25201 atatatcaag ctaatttaac acaaaggttc agtggagaaa cagaacttac aagctttgaa
    25261 ttgtataggg acttaagaag atttagccca gcaccatttg gggcattctt aaactttgaa
    25321 gatacacata tattatcaaa ttctccagaa agatttataa gatgtgttaa taagagaata
    25381 gaaactagac caataaaagg tactcgtcca agagggaaag ataaagaaga agatttaaga
    25441 cttcaacaag aacttagaaa tagtgaaaaa gatagagctg aactacttat gatagtagat
    25501 ttagaaagaa atgatattgg cagaatatct aaaactggaa gtgttaaagt tccagagcta
    25561 tttgtaattg aaccatatgc aaatgtaaat cacttagttt ccacagttgt aggtgagtta
    25621 aaagatgata aagatgttac tgatgtaata aaagcaactt ttccaggggg gtctataaca
    25681 ggagcaccta agattagagc aatggaaatt atagacgaat tagagccaac gcaaagaaat
    25741 gtatatactg gttcaatagg ttatataggt tttaatgatg atatggattt taatatagca
    25801 attagaacaa taatcaaaaa tgacaaaaaa gtctactttc aagttggagg aggaatgact
    25861 tgggattctg acccagatga agaatatcaa gaaacacttg ataaagctaa atccataatg
    25921 aaggctttga ggggatatta tgaagaataa tgtaggtttt gatagtagtt taagtaaatt
    25981 tggaattggt ttgtttgaaa ctattagagt taaaaatgga atagcagtag atttagatat
    26041 ccatatagaa agaatgctaa gctcaataaa ttgtttggat ttagatataa actataaaaa
    26101 agatttcttg ataaatgaaa ttgttacata tataaaaaaa gaaaatgtca ttaataaagc
    26161 acttagaatt actgtttttg atgaaggtta taatatatct attagggata ttccatataa
    26221 tcaagagacg tatgagaagg ggtttaaatt agctatatct ccaatagtta gggggaatag
    26281 tttaattcat agacataaga ctactaatta ttttgaaaac atatatacca aaaatatcgc
    26341 aaataagact ggttataatg atggtatatt tttaaattca gaaggtgtaa tattagaatg
    26401 ttctatgagc aatattttct ttataaaagg agaaagagtg tacactccta gtgatagatt
    26461 accgatatta aatggaataa taaaaaaaag gattatagag atttgtgacg aattacatat
    26521 agagttgata gaaaatgaaa ttaatatatc agaaattagt agttttgatt ttgtttttgt
    26581 cacaaatagt cttatgggcg ctataaaggt tacagaaatt gacaaaataa aatttaataa
    26641 agaaaatgtt gtttttgata aaatagtgaa gttattagaa taaattaaaa tattaacaat
    26701 ttgttggaga caaaagatga taggttgtat ttatgaagta tacaatgaag agatgactaa
    26761 aataatagaa aaccaaaaca ctttggctgt atatttagtg ggttctagta aagatgtaga
    26821 ttttactctt tatgatgtag tgataaacga tattgatgtg ttcgtttttg taaaagaagg
    26881 ggaaaaacaa gagagaatac tgtttaaaaa aaagggaata gaatttgatg taaattactt
    26941 ttcaaaagat ggtgtaaaaa aattattatc aaatagggaa tatttctttg tgaaagaaat
    27001 gaaagatgct aaagtactgt ttgataggga gaatatatca catattataa aagatataag
    27061 tagagatatt tacttagaag gacctagtaa aatgtcatta gaggaaaagt cttttataaa
    27121 gcaagatatt ggagcaaaaa tattgaattt aaaaaataaa gaaaaatttg atgtttttga
    27181 atatcatttt ttgacgaatt tatatttaaa agatataata attgggtact ttaatataaa
    27241 tgataaatgg gtaccaaaag acaaaaaatt gctaaaagtt ttaaaaaaag aaaataatga
    27301 gctttttgaa ctagtgtcaa aagtaagtga aaattatgac tatcaaagac ttttagatgt
    27361 ttataattat atttttaaag aaattgagac aaaagaggtt ataaaactaa tcttctagtc
    27421 acaaatcaat ggggggagtt taaatgaata aagttgataa agaaaagata caacatgcag
    27481 taagagaaat actagaggca attggggaag acccagatag agaaggtcta atcgaaactc
    27541 caaatagagt tgctaggatg tatgaagaga tattctctgg tcttagtgaa gaaccaagag
    27601 accatttaaa agttcttttt gcagatgaaa aacatgaaga gttagtattg gtaaaagata
    27661 ttccatttta ttcatgttgt gagcatcatc tagttccttt ctttggaaaa gctcatattg
    27721 cttatttacc aaaaggagga agacttacag ggctttctaa acttgctaga gtaatagata
    27781 cattggcaaa aagaccacaa ttacaagaaa gaatcactaa aaatgctgca gatataataa
    27841 tggaagaatt acaaccttat ggtgtcttag tagtagtaga agctgaacat atgtgcatga
    27901 caatgagagg cgtaaaaaaa ccaggttcaa aaactgttac atcagcagtg agaggaatat
    27961 ttgaaaagga cattgcgtct agagccgagg ctatgagttt gattactatg aagtagtaat
    28021 ttattataga tataatcatt tattgagata aaatttaatt taagggagtg tcattaattg
    28081 tgtttgatta tggtaaaaga acttatataa tgggaatatt aaatgtaact ccagatagtt
    28141 tttctgatgg aggagatttt aataacttgg acatagcaat acaacatgca aaagatatgg
    28201 ttgaccaagg tgcagatata atagacctag gaggagagtc tacacgccca ggtcatagct
    28261 atgtagactc agacgaagag ctaagaagag taatccctgt aataaaaaaa cttaaacagg
    28321 aattggatat accaatatca atagacactt ataaggcaga tgttgcagaa gaagcattaa
    28381 aattaggtgt cactatggta aatgatgttt ggggtcttag aaaagataaa aatatggctt
    28441 ctgtaatagg aaaatatgat gcagaagtgt gtataatgca taatcaagat gggacaaact
    28501 atgacaaaga tataatggag tcaataaaag acttttttaa ggtaagtata gaaatggcaa
    28561 tgagttgtgg tgtaaaaaaa gaaaaaatag tacttgaccc aggtatagga tttggcaagg
    28621 attttgaaca aaatattgaa gtattgagaa gattaaatga attaaaagat ttagggtatc
    28681 ctattttgct tgggacatcc agaaaatcag taataggaaa agtacttcca gttgagccta
    28741 aaaaaagatt agaaggtaca atagctacta ctgttcttgg tataagagat ggcgtagata
    28801 tagttagagt acatgatgtt tatgaaaatt taatggcagc tagaatgact gatgcaatat
    28861 atagaaagta ggtataatat aatggataaa atattactta gtaatctagg attctatgga
    28921 tatcatggtg ttcttaaaga agaaaatttt ctaggtcaga aattctttgt cgacatggaa
    28981 ctttatattg attcaagaga agcaggtctt agtgacgata taaataaatc tgtaagctat
    29041 gccgaggttt acaatgttgt taaagatatt actgaaaata aacaatttaa tcttttggag
    29101 gctttagcgg aaaatattgc tgaagaagtc ttgaataaat ttatacttat aaatggagtt
    29161 atggtcagag ttagaaagcc tgaggctcct gtaaatggta tttatgacta ttttggtgtt
    29221 gagataagga gaacaagaga tgaataaggc ttatttggga ataggtacta acatgggtga
    29281 tagatttgat aatttatcaa gagcatgtga acttttgaaa aatagtgatt ctatatataa
    29341 agtaaaagaa tcaagcttat acgaaacaaa accatgggga tatacagaac aagcagattt
    29401 tctaaatatg tgtgtagaaa tagaaacaga gtttgaacct tatgagttgt tagaatattg
    29461 tcaagaaata gagagagaac tacacagaga gagaatagtt cattggggac caagaactat
    29521 agatgtagac gtactatttt ttaatgatgt agtttccact gatgaaagac taacaatacc
    29581 tcatccaagg attcaagata gagctttcgt tttgatacca cttatggatt taaatgaaaa
    29641 acttataata aatgaaaaaa caataaaaga acatttaaac ctcctatctg ctgaagaaag
    29701 agaagaagta aaggagcttg taggttatga aagaaaacct atttaataat aattcaaaga
    29761 tagagataaa tacaaataac aaaaagataa ctgtaaaaaa agataaactt ataatagctg
    29821 gaccatgtgc aatagagagt tatgagcaac ttttggagac tgctaaattt gtaaaaagtc
    29881 agggagcaaa tattttaaga ggtggagcat acaagccaag aacatctcca aattcatttc
    29941 aaggattaaa aaaagaaggt cttgaaatat taaaagcggt taaagatgaa gttggtatgg
    30001 ctgttattac agaacttatg gatgtaagag atatggacga actgtatagt ataagtgata
    30061 taattcaaat tgggtcaaga aatatgcaaa actttactct tttaagtgaa gtgggaaaac
    30121 aaaataaacc tgttatgtta aaaagaggaa tagcatccac aattactgaa tggataggtg
    30181 cttctgaata tatagcaata gaaggaaata gtaatattat aatgtgtgag agaggtataa
    30241 gaacgtataa tgattatact agaaatacat tagatttagc tgcggtaccc attattcaaa
    30301 aggaaacagg tcttcctgtt gtggtagacc caagccatgc cactggagtt agatatttgg
    30361 taaaacctat gtcactggca tcttttgcat gtggagcaga tggaataatg gtagaagtac
    30421 atcctgaccc agaaaatgct ttgtcagatg gtgctcaatc tctttgcttt aatgaatttg
    30481 aagatttaat gaaatcaatt aataattatt aaaagaggca agagcctctt ttttattcgt
    30541 aatcgttgct aaggtaaatt tataagttat aatttgatag ttagattatt taatataaat
    30601 aaagatttaa tattgataga attaatataa aaaataaaaa ttttttgatt aataagaagg
    30661 atatcaataa aaaaagtcga attgtgtata ttgagtgatt gacaaattta gaatatagtg
    30721 tagaatagaa atgttaacac aaaaaattac accagaaggt gataatatga atgatataaa
    30781 agacattatt gaagaaataa aagctagatg cgatatagca agtataatat ctgaatatat
    30841 gaatataaaa caatctggag ctaattacaa aggattatgt ccatttcatg gcgaaaagac
    30901 accttctttt tatataaata catcaaaaca gatttataag tgttttggtt gtggtgaagg
    30961 tggagacgta ataaattttg tcatgaaaat ggaaaatttg gattttatgg atgctgtaaa
    31021 aattttagca aataaatgcg gtatagaaat taacactaac atgaatgaag aaactaggat
    31081 taaaatagaa aaatctaaga aatttcaaga tattcatacg gaagcagcta gattttatct
    31141 ttcaaactta ttgggaagca aaaatcttgg gtatgaatat ttaagaataa gaggactaga
    31201 tgataaaatt attaagaaat ttggtttagg attttctttg gattcatgga attcacttat
    31261 gaatactcta atcagtaaag gatataaaaa acaagactta ttggagtgcg gtctaattgc
    31321 aaaaaataga gatggaacta attgctatga taaatttaga aatagagtta tgtttcctat
    31381 attcgattat agaggaaata taataggatt tgggggaaga gtattagacg attctttgcc
    31441 aaaatactta aattctccag acacattaat ttttaataaa aaacagaact tatacggatt
    31501 aaattttgct agaaaaaatt tagaaagtaa aactatagtc ttagttgaag gatatatgga
    31561 tttaatttcg ctttatcagt atggtataaa aaatgtagta gcaacccttg gaacagcctt
    31621 gactgaacaa caaggcattt taataaagag atatgcggac actgctatta tatcttatga
    31681 ttctgatgaa gcaggaataa aagcgacttt aagagctata gatatactta ctaaattagg
    31741 tatcaatgta aaagtgttag acttaaaaga tgctaaagac ccagatgaat ttgtaagaaa
    31801 atacggactt agtgattata aaaaagctat ggatgtttct actcactaca taaaatataa
    31861 aatagatcat cttaaaaaag aatttaacat tcaaaaagat gaagaacgag tgaagttcgc
    31921 aaaagaagct tctaaaatta taaaacaatt gacaagtcct gttgaaattg atttttatac
    31981 aaagtattta agcaatcaaa tagatattaa tgtcgagtct ataaagagag aagtttatgg
    32041 taaaaattac aataagccat ataataacaa aaatcaaaag aaaatagaag aaaaagtaat
    32101 tgaaaaagtc gaagtcagac aagacggaaa acaattagtt gaagaaactc taataaaaat
    32161 aatgttagaa gacaaaaaaa ttagagaaat agcgttactt aaagtagaag aaagtgattt
    32221 tttattgaaa gaaagtaaag aaattttaaa ttacatgatt aaaaatcaag aattggacaa
    32281 aataactatt gacaaattga aaagtttaaa catatccgaa gaatacttaa aagaattaaa
    32341 ttcaatttct ttgaatagta taaacttaga gaacacaaaa gaaatagaag gaataataac
    32401 aaatatcaga aaaaactcat tagaagagca aattaatagc ttgttgagag aacaacaaga
    32461 attagaaaat aataatgata tgaaagaggt agatggtaga gttatggaaa ttgctttaaa
    32521 aatagttgag ataaataaaa ttttaaagag cttgtagaga aaggaggttt gagtgtggaa
    32581 aataaatcga ataaaaaaga gttaaaaaag gttactgcta agacattaat agaaaaagga
    32641 aaaaagcaag gttctctgac acttgcagag ataatggaag ctttttcgga gactgaactt
    32701 gataaggatc aagtagaaaa tctttatgag actttaggaa atttgggaat agaaataaca
    32761 gaaacaaaaa actataaagc tgatatagat ttttcggttg ctgatgacga tttaagtata
    32821 ggccacttag atgaagatgc agaggcaatt tcacatgatg actcttctgc aatagaaata
    32881 gaaactgtgg atttatcttt accaaaaggg ataagtatag atgaccctgt aagaatgtac
    32941 ttaaaagaaa taggaaaaat tcctctactt aaaccacatg aagaagtaga atttgctaga
    33001 aggatgcacg aaggtgatga gatagcaaaa caaaggttag ttgaagcaaa cttaagacta
    33061 gttgtaagta tagcaaaaag atatgtagga agaggtatgc ttttcttgga tttaatacaa
    33121 gagggaaatt taggtcttat aaaagcagtc gaaaaatttg actatacaaa aggatataag
    33181 tttagtactt atgcaacatg gtggataaga caagctataa cacgtgctat tgcagaccaa
    33241 gctagaacta taagaatacc agttcatatg gtagagacta taaataagct aataagagta
    33301 tcaagacaac tacttcaaga acttggaaga gatccaaaac cagaagaaat tgcaaaagaa
    33361 atggaaatga cagaagataa agtaagagaa ataatgaaaa tagctcaaga ccctgtgtct
    33421 ttagaaacac caataggaga agaagaagat agtcatttag gtgactttat tccagatgat
    33481 gatgctccag ccccagcaga ggcagcagca tattctttat taaaagaaca aatagaagat
    33541 gtacttggtt cattaaatga tagagaacaa aaagtattaa agcttagatt tggtcttgag
    33601 gatggtagag ccagaactct tgaggaagtt ggaaaagagt ttgatgtaac tagagagaga
    33661 ataagacaga tagaagcaaa agcactaaga aaactaagac atccaagtag atcaaaaaaa
    33721 cttagagatt atttagacta aaaagataca tcattgatgt ttttgtgata aatgccatga
    33781 gataagtgat atctcatggc tattttgtag taaagattta attttatttt tgtagttatt
    33841 tcagtctaat atctataact tggattaaat cctataaata aagggaattg aaaggagaat
    33901 tatatttgaa attaacagat agattattga aaatagcatc attagtgtca gatggtaaaa
    33961 aaatagctga tatagggacg gaccacggat acataccagt atatttgtta aaagagggaa
    34021 aagtaccatt tgcagtgcta gcggatgtta ataaaggacc tcttgacaat gcacataaag
    34081 aagtcataca gaacaatctt ttagataaag ttgatttacg attgggttct ggtatagaga
    34141 tacttgaaat aggggaagta gaagaagtga taattgctgg tatgggtgga atcttgataa
    34201 gtgagcttct cgaagctaaa aaagaagtag cacataatgt agaaaaatta atattacagc
    34261 caatgcaagc acaagaagaa cttagatatt accttttaaa caacggatat gaaattttag
    34321 aagaagtttt agtgagagaa gattttagaa tatatgagat aattgttgcc aaatatacag
    34381 gtaaaaatac tataatagaa gatgagatat attatgaggt tggaataaag cttttagaaa
    34441 acaaagattc tctttttaat gattttatag aaaaaaagat aaagacatat agttctatag
    34501 ttaataaatt agaagggaaa aatggggaag ctatagataa gaagagaaag gaaagcgaag
    34561 ttgcaataaa aaaacttgaa aatttaataa aataaatagg aggtatatat gctattaaag
    34621 agtctaacta gaaaaattga aaaaaagtat cctctaaact tagcagagga ttgggataat
    34681 gtaggtctta tagttggaga ttttgatatg gatgtaaaaa aggtattggt atctttagaa
    34741 gctaatgaag atgttattga tgaagctata tccaaaaata tagatttaat tgtgacacat
    34801 catcctttta tatttgggaa aattaataaa attaatagtg gggatttaaa aggcagactt
    34861 atccaaaaac ttattaaaaa tgatatatca ctttattcta tgcatacgaa ttttgatata
    34921 gcatttgatg gtctaaatga ctattttatg gaaattatgg aatttggtaa ttcaaaggtt
    34981 ttagatataa ctaaaagcga aaatttgtat aaattagcag tatacgttcc acataactat
    35041 tcagatgaac ttagaaaggt tttaagtaat tcaggagcag gtcatatagg gaattatagt
    35101 gattgtacgt tttcaataga aggtgaagga caatttaagc cactagaagg ctctaatccg
    35161 tttcttggaa gtgtaaatga tatagaaact gtaaatgaag ttaaaattga aactgtagta
    35221 ccacagaagc ttttaggtgg ggtaataagt tctatgttag atgcacatcc ttatgaagaa
    35281 gttgcatatg atttgtacaa gttagaaaat aaaggtgaga tatttggact aggtagaata
    35341 agtaaacttg ataaaagtat gacattagaa agtctttcaa ggaaaataaa agagaaatta
    35401 aatatgaaac acataagagt agttggaaac cttagtacag acataacgaa agtagccgtt
    35461 gtaacaggag ctggttcaga atttgtaaaa aaagctaaga gacaaggtgc agaagtacta
    35521 attacgggtg atgtaaagta tcatgaggca caagatgcac ttgatattgg aatgtgtata
    35581 gtggattgtg gtcattttga tacagaagat atattcaaaa atgttatgaa gagattttta
    35641 gatgaattta gtgaaattga agtaataaag agtaatgtat atttgaatcc atttagtact
    35701 atttagcagt gtttgataat aaaaatacta tataaaaaat aaatttgagt ttaattaggg
    35761 ggataatgat gaaagtagca gtaatttttc atagtgtttg tgggagtaca tatttattag
    35821 ctagagaata taaagaagcg cttgaagaaa tgaatatcga ggtagatata tttagagtaa
    35881 gtgacgaagt tgcaaaaaca cttcctcaat attatttgat aaattccaaa gaatacaaag
    35941 acgaatttga aagtataaat gtaattaaat ctggaaaaga aatattagat tatgatgcta
    36001 tatttatggg ttcaccaaca tattatggaa atgtatctgg accaatgaag atgtttatgg
    36061 atagtttttc tgatatttgg gtaggtgctc ctttgagtgg taaaatattt ggttgttttg
    36121 ctacagcagg ttcacaacat ggaggaggag aattagcttt gcaagctatg aatatatttg
    36181 cccaacatat gggaatgact cttttgtcag ttccatgttc agtaagagga ggttatccag
    36241 cgtatggaat acttcatata gcaggagata attctgatat aagaccaaat gatgatgcca
    36301 agataggtat aagagattac ctaaaaagac ttaacatata agaatatcat ataaaaatac
    36361 ctaaaagcga ctgtatatac ttttaggtat ttttacttaa ttataaacgt gaagctttac
    36421 cagaaatatg gtcaatttct attttaacaa cagttgttaa gttcatatcc ttctctatgt
    36481 acttcatgcc ttcttcaaag aatcctttag aatatttttt tattatttct acaagagcat
    36541 ttttcttttc ttcattttct acagtgcaag cttttccaaa aactatagca ctagaataag
    36601 tagtactaaa tttatctgga ataacacttt cattagcaac tactaaaaaa gaaactttgt
    36661 tgtttttcga tatattatct aacttatgcc catttcttgc acaatgaaag taaatagaat
    36721 cattaaagta tacataattt acagcaactc cataaggata accattttca gatatagtgg
    36781 aaaaagtacc aaattcacca ttttttaata cttcaacagt atcttctttt gtcatttctc
    36841 tttttttcaa tctcatttct ttaaacataa tatcatcctt tctaattttg atgcttaaat
    36901 taaattttag aacatttata aagattatgc tatgtttttt acaaatttta agaaaaaaat
    36961 atagtttaag ataaaaggta gtgaaagaga agctatttgg aggtttattt atgatattat
    37021 tgttagagta gtataaacaa tactaataaa tttaatagct ggtttcttgt tatttaaggt
    37081 agtaagcatg tctataagaa ggggaagtta tcgagggtag aagttgttat ttataacgat
    37141 attataaaga aaatattatt atataaaata ataaatagta aagaggtatc aagttgaata
    37201 taatacttaa tacctcttca aaattaagtt ataaaagtgt cgtgggaatt gtcctataca
    37261 tggtaaggag ataataaaga atgtatcttt aaagtctcaa ctaaacagca aaatttatcc
    37321 aacaaacata caataaatgc ttctttgtat ctaggtggct taacagtaag tggccacatg
    37381 tgttttaaaa ttatgtccgt ttctttttca tttatttgaa aaaataaagt tgcatttttt
    37441 aatgcttctc tagggtgagt aaatccatgt aatccttttc tatcaccttt gtaatgccaa
    37501 tcataaagaa aaaagtcgtg tagtaaagct cctctaataa cactttgaat atcaacactt
    37561 aagtgcaatt ttttacataa tagataacta taatatgcta ctgacaaact atgttcaaga
    37621 catgaaacat tgccatgatg aggaaatgtt ctcataagtt gaactttttc agaagaaagt
    37681 atctcagaag cacattcatt aaaatatttg atttcagctt ttgacaacat tatgaaaatc
    37741 tccattctta gtaatatata aatactatac ttcaacgata atatgaaata tttcttatcc
    37801 tacaaaatat aatacccaat aatacaagta agataccttt tatggtattt taaagtaaga
    37861 gagattttat taggctaaac aatgaaaaaa ttaaaagtaa agctatagca atatatagta
    37921 tttttccaag aggattgcca aaatttatag tccatccaat accaaacctt ttattaacca
    37981 ttaatgatgg gtcatttgga ttattataca tgatgcctgc tatccaatac ttctcatctt
    38041 cttctggaga ataagatgag ttgaatttta aatttgggga attaatatat gttgctatta
    38101 aataaattat aactaaaagc gttgtaatat tcatagcagt tgatagtttt gtttttattg
    38161 ataaaagagt agtaaaaaac tgtgttgtca ttataatcat caatattaaa aacaaataac
    38221 caattttatt taaatattta atgttttcaa ctctactttc ttcaattcta tttgtatcta
    38281 tcttaatcct tgactttatg gatccaatgg aagttatata taataaaacc attaaacaaa
    38341 agtcagtacc gattaattta aatacattaa gaaatgattt atctataaaa acatcaggag
    38401 acccatttat gttccaatga gtggcaattg agtctggcaa ttgattataa ttaaatgcta
    38461 taaaaatact cattcccaaa gtaaatagta tcggtattaa atagattatt ttaaattttt
    38521 ttattatttt atttttctta tttataaaat ccatatctac tattaatttt gaatctatat
    38581 ctatatgacc taatttagca taaatttctg atttaagctt cttagctttt ttatgtgtat
    38641 gaatatatag tatactttca tataataaaa aacctataat accaataaaa taggaaagtt
    38701 ccaatttatt aaatgtaaaa accagaataa aaactaatat aaagtctata ataaaaccta
    38761 aagataatag ttttttaaat tctttatcta actttataaa gtaattataa tttttatgct
    38821 cttggtctat agaaactcca tagatgtgtt ttttacctac aaaatagggt ataaaataaa
    38881 atgtagcata catcaaaatt agaactggaa atattgtaaa tagacattca atcttactca
    38941 taatatttca cctcatactt gtcaaataaa cttgaactta gtgacaaaaa ttcttcttta
    39001 ctaatacctg ataaataaga ttttgctacc aataattcca agtcaagttt atttttttga
    39061 cgagttgtat tatctatttt cattggtagt tgagctacaa tagcaccttt tcttctatca
    39121 atatttaaga atccctcttc ttttaattca ttgtaggatt tgttcactgt atgtaaattt
    39181 acaccaatat tttcagccat acttcttaca gatggaagtg attcatttat tttcaattct
    39241 cctgaagcta tagccttagt tatttcttct ttaatttgta cataaataga tttatcacta
    39301 ttaaaatcta aatttaaaac cataaaaaac ctccattatg ctttataaat gaaaacgatt
    39361 gttatataca tagtataaca taaaaaataa taacaaacac aaaatataag tttatatttt
    39421 gtaaaaattg taatttaaaa aataacataa tttttattaa aataatacag atactattta
    39481 tagatagaaa taaaaattag aaaggagaaa aaatatgtta acatatttaa tgaaaagaca
    39541 aatgcataaa aaagatgatg gaatgagtaa accaatgatg attacaggag ctgtaattac
    39601 aggtgtagga gcatatgctg tatataaaat ggtaaaaagc cataaatcta attctcaaat
    39661 ggtcaataca aattattatg gaaatagcga ttatgatgat tataaatatg acgaatttga
    39721 ttatgactgt gattgtagag acacaaaaca agattatgaa tatgaagaat taaaaaaaaa
    39781 agtaaaagaa tttaattcaa gaagaataaa ttgtgaaaat tgtccacatg tttctcaaga
    39841 agaaatgatg caatatgtaa atagtgttaa agatgtaaag gaagagattg atttacatga
    39901 agatgctaaa aaagataata tttacaaaga agatgaatac aaaaaatatg aagaagaata
    39961 agtaatattt tgtataactg aacaaatagt aatgtcaaat tatttaatat ctagttttaa
    40021 tatgtaagtt gtaacttaac ttgaaagaat cagtatcatt ctttagatag ttaagttaca
    40081 acttacattt tgtttttata aattttaata gctctttgtg actattttgt aattttagaa
    40141 atattttagt atccagggta attgtgtata ataaaacttg tatagataga tagtatgaaa
    40201 ttaagcagat agtttaaaat taaaatgaaa agaaaggaaa tagttatgtt aaagttgttg
    40261 atagttgaag atgatagtac tatatctttt ggaataaagt atgctttaga acaagaagga
    40321 tttagtatag atatatcaaa ggatttatct agtggaaaag aaatgatttc ttctaatgaa
    40381 tatagcatga tactgttgga tgttacattg ccagatggaa ctggttatga gctttgtcaa
    40441 tatataagag gattctctca ggttcctata atattcttga ctgcttgtga tgaagaagta
    40501 aatattgtaa tgggtctcga tataggtgga gatgattata taacaaaacc ttttagaatt
    40561 agagaattaa tatccagaat aaaagctgtt ttaagaagaa aaggtaatac ttcagaagaa
    40621 aataagaaaa tacttaaatt tggagattta agtatatata cattagaagc tagagtatat
    40681 aaaaatgata aagaaatatt tctgacatca gttgaatata aacttctttt aattcttata
    40741 cagaataaaa atactgtttt aagtagaact caaatattgg aaaaactttg ggatgtaact
    40801 tatgattttg taaacgacaa tactctaact gtttatataa aaaggcttag agaaaaaata
    40861 ggtgatgatt tatgtgaacc aatctacata gaaactgtaa gggggattgg ttataaatgg
    40921 ataggaagtg aaaatagtgt ttctatataa tccagaagtg aagaagtttt taagtaagta
    40981 tgttactttg atgtttattg ttatcataat atctattgga tttagcataa tcaacgtgtc
    41041 cttaactaaa gagatggttg taagaaataa tcaggctata ataggaactt tatcaagcaa
    41101 gtatccaaac ttagaaagtc agatagtaga cataataact caagggaagt ctatggagaa
    41161 catagattat ggtcagaaaa tattaattaa gtataattat gataaatcta ttaggataaa
    41221 ctctgagcct attatttcta aattagtttt agagactatc aaaataaata taatattagt
    41281 atgtataata tttattttga tatttgtgtt ggttgttaga tattttaagt caatttacaa
    41341 tgatttatca gatatgacta agtatgttta ctatagttca gagggtaagc catttgatat
    41401 gaaaaacaag aatcaagaag ggcagatagg tcttctaaaa actgaactct taaaaatgac
    41461 gacaattctt aatgaaaagg ttgaactttt aaaaagagaa aagatatttt taaacaatac
    41521 aatttccgat atatcacatc aattaaaaac tcctatgact tctttaataa tgttgaatga
    41581 tttattatat aatgatgtac catacgaagt aaaaatcgat tttttaaata agataaaaaa
    41641 tcaattaaat agaatggatt ggttgattaa aagcatgctt aaattatcaa aggtagaagc
    41701 aaaagtgata aattttaaaa aagataaggt aaaatttagt gaactcatac atagagcaat
    41761 gctatctatg aaaataccta tggagattaa aaatcaaaaa ctgactatag agggaaatga
    41821 taatgtatct tatattggtg atattgattg gtccgtggaa gcattagtga atataatcaa
    41881 aaattgtgta gaacatactc ctgaatttgg aaatataatt ataacctata aagaaaatcc
    41941 attattttct gaactaataa taaaagatga gggtgaaggt atagataaaa aagatatacc
    42001 acatgtattt aaacgattct atagaggaag aagtagttca aaagaagata gtgtaggaat
    42061 aggtcttgca atgtcaaaat ctataataga aagccaaaat ggcgatatat atgtaaacag
    42121 cgaaaaaggt aagggtacag aatttcatat aatatttcat aaaatgtatg atagtgacta
    42181 atctgtaata tttaattcac tttatagtaa tagacaaaac ctaatatatg aagtatagaa
    42241 tataaatatt ggaggtagtt atggaaattt taagagtaga aaatctaact aaaagttatg
    42301 gtaaaaatga aacaaaagtt gatgctataa aaaatgtaag tttatcagtt gaaaaaggaa
    42361 cgtttatagc aataacaggt ccaagtggaa gtggtaaaag taccttatta catttattag
    42421 gaggagttga cagaccaact agtggtaagg tttatataaa tgatgttgat atctataatt
    42481 taaaaactaa ggatttggcg atatttagaa gaagaaatat aggtcttata tatcaatttt
    42541 acaacttaat tccagtctta aatgtgaagg aaaatatatt gcttccagca gagcttgaca
    42601 atagagatat tgatagagaa tattttgatg atttaatgaa aacattaggt ctaattgata
    42661 gagaaaatca ccttccaaac caattatcag gaggtcaaca acagagaacc tctataggac
    42721 gtgcattaat taatagacct tctataatat tagcagatga gccaacaggt aatttagata
    42781 gtaaaaattc aaaggaaata ttagaattgt taaaattgtc agtaaaaaaa tacaaccaga
    42841 cactaataat gataactcat gacaaaaata tggcacttca agctgataga attataagca
    42901 tagaagatgg aatcataaaa agtgatgagg tgatgtagat gaatttatat acatcactaa
    42961 ccattagata cttaaaacaa aataaaagaa gaaccattgt aaccataatc ggtataatac
    43021 tttcaacagc tttaatttgt ggtataggaa atatatttga aagttttatg gattatcaaa
    43081 tgagagaaac tataaagaat gatggaagtt tccatgttac attttatgat gtaaatagaa
    43141 aaaatgcgga atatgtaacg aaatcagctg aaatagaaaa acatgcattt accaaacaac
    43201 ttggatattc taaattagaa aatagtgaaa atgctatatt aagtataaag caatatgata
    43261 aaaatgcaat aaatggatat aaagtttcta taaaagaagg tagatttcca gctaaggaag
    43321 gagaaattgt tttaagtgaa agtattatta atcttataga tgataagttt aaaataggag
    43381 ataagataac tttaaaagta ggggatatgt ttgactcaag caagaaaaag attgatagta
    43441 tgacatttca tgaaggtgat tatatagcaa atgaaaaaga tagaactttt aaagttgttg
    43501 gtataattga aaaacctggg tttgaacgtt ataatggaat tgcaacagct atagcctact
    43561 ttaatcctat gaataattac aatgatacaa ttaatgtatc agtagcagta agaaatccta
    43621 aagatgtgta taagataagt aataaaataa gtaaaaatat atattcaaat aaagataaag
    43681 aagcagtttc tgatatgata aaatacaatg aacatttatt gaggttacaa ggtgctagta
    43741 agtattcaaa tataaatagc tctataaagt ctataattat agcagtaact attttagtaa
    43801 tcatatgtac aattgctaca gtgtacaatt cctttagtat ttctataaat gaacgaaaaa
    43861 aacagtttgg gatattaaat tctataggtg ctacatctag tcaaattaaa agattagttt
    43921 ttatagaagg tattataatt agtttaattg gtataccaat aggactaata tctggaacag
    43981 tagctataga cttattgttt aaaattataa ataagtattt tactgaatcg gttgttacta
    44041 agatgagttt gcagatagtg tataatccaa taataattat tgttagtata ataatagttt
    44101 tgcttacaat ctttatatca attctactac ctgcaatatc ggcttctaat atttctcccc
    44161 tcaatgtgat taaaaatact ggagagtata aagtgggcaa aatcaaaagc tcaagactta
    44221 ttaaaatgat ttttaaaact gaaggagtac ttgcatataa aaatattagg agaaatagaa
    44281 aaaaatttat aataactctt ttttctttaa tggtaagtat aataatattt atatctttta
    44341 gtggctttac attactttta ctaagaggtg aagaaattag aaattctcaa agaaaatatg
    44401 atttgtattt aactgcaaag aacacagcta ggtctgtaga ggatactata attgaactag
    44461 aagatattga tgggataaaa aactttgaat tggcaacagg acaatatgtg tctataagag
    44521 taagtgaaaa taaaataaat aaatccaagg aagatttaat caggaaatat tatcaaaaat
    44581 ataagattgg agatagttat gaatatgatt tcagtaataa tgaattaatt tttccaggag
    44641 attttgcagt aaaaaacaaa ataaataact tagtacaggg ctcttttaat aaagagagag
    44701 caattgaaga aaatggtgtt atattagtta gaaaaagtgc atttgaagaa aatgggaaga
    44761 aaggtgtagt agaacttacc aactataaag taggagatac agtaaattgt gaatatcttg
    44821 atgaaaatgc cttaagtaaa aaagtaaagg tcaagattct tgctataact gatgaagaac
    44881 gtctaggtct tggttatcaa aatatggggt tacaatttat aacttatgat gaagttgcta
    44941 aaaatttaaa tttaaaatta agtaaaagcc ttatatttat tgattcagga ggaagcatta
    45001 agactaagaa ggaaatagaa gctttggcaa ataaaaataa ttttaacttt tatgatgaaa
    45061 gtgcaagcaa tgaaagtgaa aaacaagatt taaaggttat taaaatattt gtatatggtt
    45121 ttatagtagt gatatcttta gtgagtgtta caaatattct aaatacagta agtacaagta
    45181 taaatctaag aaaaagagaa cttgcagtaa tacaatctat aggggttact cctaaaggat
    45241 ttaggaaaat gatatattta gaaagtttta tatatggtat actgtcattg ttgtttggaa
    45301 taccaattag tattggtata attctaatta tgaataaact tatttcaggt gtaattgaat
    45361 tttctccgat tataccatgg acagccatag ttatctgtat agtaagtgtt tttataataa
    45421 cttttatagc agggtatata ccaatgagta aattaaataa agaaaatata
//
LOCUS       DAEQAF010000020        44481 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.021, whole genome shotgun sequence.
ACCESSION   DAEQAF010000020 DAEQAF010000000
VERSION     DAEQAF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.021"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(254..718)
                     /locus_tag="KRN00_001241"
     CDS             complement(254..718)
                     /locus_tag="KRN00_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HBH1827108.1"
                     /translation="MKKLVIILISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFRVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNTWH
                     GSVNNDTFTISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            complement(1042..1650)
                     /locus_tag="KRN00_001242"
     CDS             complement(1042..1650)
                     /locus_tag="KRN00_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1827109.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            complement(1732..2433)
                     /locus_tag="KRN00_001243"
     CDS             complement(1732..2433)
                     /locus_tag="KRN00_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827110.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            2645..2911
                     /locus_tag="KRN00_001244"
     CDS             2645..2911
                     /locus_tag="KRN00_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBH1827111.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            complement(3014..3433)
                     /locus_tag="KRN00_001245"
     CDS             complement(3014..3433)
                     /locus_tag="KRN00_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBH1827112.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNRKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(3700..4482)
                     /locus_tag="KRN00_001246"
     CDS             complement(3700..4482)
                     /locus_tag="KRN00_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH1827113.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKDKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKRIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            complement(4547..5308)
                     /locus_tag="KRN00_001247"
     CDS             complement(4547..5308)
                     /locus_tag="KRN00_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBH1827114.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITASSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEKCIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            complement(6357..7169)
                     /locus_tag="KRN00_001248"
     CDS             complement(6357..7169)
                     /locus_tag="KRN00_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1827115.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTIGLVLQK"
     gene            complement(7539..8441)
                     /locus_tag="KRN00_001249"
     CDS             complement(7539..8441)
                     /locus_tag="KRN00_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1827116.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELLDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
     gene            complement(8491..8952)
                     /locus_tag="KRN00_001250"
     CDS             complement(8491..8952)
                     /locus_tag="KRN00_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBH1827117.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHLLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKAYELWSGNIMF"
     gene            complement(9004..9459)
                     /gene="def"
                     /locus_tag="KRN00_001251"
     CDS             complement(9004..9459)
                     /gene="def"
                     /locus_tag="KRN00_001251"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBH1827118.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            complement(9431..9694)
                     /locus_tag="KRN00_001252"
     CDS             complement(9431..9694)
                     /locus_tag="KRN00_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827119.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            complement(9791..10507)
                     /locus_tag="KRN00_001253"
     CDS             complement(9791..10507)
                     /locus_tag="KRN00_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827120.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFIITMILLIFFSLTKISLLLNLSISLLVLLQGVIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYVYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            complement(10504..11187)
                     /locus_tag="KRN00_001254"
     CDS             complement(10504..11187)
                     /locus_tag="KRN00_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827121.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGDKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            complement(11184..12029)
                     /locus_tag="KRN00_001255"
     CDS             complement(11184..12029)
                     /locus_tag="KRN00_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827122.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            complement(12143..12733)
                     /locus_tag="KRN00_001256"
     CDS             complement(12143..12733)
                     /locus_tag="KRN00_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1827123.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            13022..13255
                     /locus_tag="KRN00_001257"
     CDS             13022..13255
                     /locus_tag="KRN00_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBH1827124.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            complement(13486..15873)
                     /locus_tag="KRN00_001258"
     CDS             complement(13486..15873)
                     /locus_tag="KRN00_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBH1827125.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVNDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKIVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(16065..16820)
                     /locus_tag="KRN00_001259"
     CDS             complement(16065..16820)
                     /locus_tag="KRN00_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBH1827126.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNNNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            complement(16845..17996)
                     /locus_tag="KRN00_001260"
     CDS             complement(16845..17996)
                     /locus_tag="KRN00_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH1827127.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            complement(18212..18952)
                     /locus_tag="KRN00_001261"
     CDS             complement(18212..18952)
                     /locus_tag="KRN00_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBH1827128.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIRVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            complement(19024..20013)
                     /locus_tag="KRN00_001262"
     CDS             complement(19024..20013)
                     /locus_tag="KRN00_001262"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBH1827129.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHEKAYNLVKDKKILLELCPTSNVQTKTVDSYEVHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            20273..21526
                     /locus_tag="KRN00_001263"
     CDS             20273..21526
                     /locus_tag="KRN00_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBH1827130.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            21623..21847
                     /locus_tag="KRN00_001264"
     CDS             21623..21847
                     /locus_tag="KRN00_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1827131.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(22501..22986)
                     /locus_tag="KRN00_001265"
     CDS             complement(22501..22986)
                     /locus_tag="KRN00_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827132.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKSLQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKAKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(23025..24383)
                     /locus_tag="KRN00_001266"
     CDS             complement(23025..24383)
                     /locus_tag="KRN00_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1827133.1"
                     /translation="MINLFYSDLFLKYSFFFSFIVYRILMVIVQYYFLINFTNFNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            complement(24385..25116)
                     /locus_tag="KRN00_001267"
     CDS             complement(24385..25116)
                     /locus_tag="KRN00_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827134.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            complement(25404..26711)
                     /gene="grdB"
                     /locus_tag="KRN00_001268"
     CDS             complement(25404..26711)
                     /gene="grdB"
                     /locus_tag="KRN00_001268"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(25662..25664),aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH1827135.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            complement(26797..28083)
                     /locus_tag="KRN00_001269"
     CDS             complement(26797..28083)
                     /locus_tag="KRN00_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH1827136.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCKKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            complement(28362..29684)
                     /locus_tag="KRN00_001270"
     CDS             complement(28362..29684)
                     /locus_tag="KRN00_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH1827137.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            complement(29684..31678)
                     /locus_tag="KRN00_001271"
     CDS             complement(29684..31678)
                     /locus_tag="KRN00_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1827138.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDAVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIRNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDALKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            complement(31765..33012)
                     /locus_tag="KRN00_001272"
     CDS             complement(31765..33012)
                     /locus_tag="KRN00_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1827139.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSAGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            33240..33785
                     /locus_tag="KRN00_001273"
     CDS             33240..33785
                     /locus_tag="KRN00_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1827140.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLDGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            33799..34485
                     /locus_tag="KRN00_001274"
     CDS             33799..34485
                     /locus_tag="KRN00_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBH1827141.1"
                     /translation="MKIYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDILGGINSGIDTCWLNSNNSINYTNHIPAYEI
                     NTLIELKKLL"
     gene            complement(34609..35229)
                     /locus_tag="KRN00_001275"
     CDS             complement(34609..35229)
                     /locus_tag="KRN00_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827142.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKIGIVCLDYINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(35219..36241)
                     /locus_tag="KRN00_001276"
     CDS             complement(35219..36241)
                     /locus_tag="KRN00_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HBH1827143.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRGYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            complement(36242..36880)
                     /locus_tag="KRN00_001277"
     CDS             complement(36242..36880)
                     /locus_tag="KRN00_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH1827144.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            complement(36998..38149)
                     /locus_tag="KRN00_001278"
     CDS             complement(36998..38149)
                     /locus_tag="KRN00_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1827145.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRSHKPTMMEEFPLLLSK
                     NNIENMIIISKDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            38571..39383
                     /locus_tag="KRN00_001279"
     CDS             38571..39383
                     /locus_tag="KRN00_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBH1827146.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            complement(39472..39663)
                     /locus_tag="KRN00_001280"
     CDS             complement(39472..39663)
                     /locus_tag="KRN00_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827147.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            39968..40174
                     /locus_tag="KRN00_001281"
     CDS             39968..40174
                     /locus_tag="KRN00_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1827148.1"
                     /translation="MFKKKSGYTFTNFLSKVRVEKSKKYILKKNLSILDVAVLIGFNS
                     QNYYSIIFKKFNNFTPIEYKNIYN"
     gene            40472..42091
                     /locus_tag="KRN00_001282"
     CDS             40472..42091
                     /locus_tag="KRN00_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH1827149.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKSFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            42465..42659
                     /locus_tag="KRN00_001283"
     CDS             42465..42659
                     /locus_tag="KRN00_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1827150.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(43218..43541)
                     /locus_tag="KRN00_001284"
     CDS             complement(43218..43541)
                     /locus_tag="KRN00_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827151.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(43586..43840)
                     /locus_tag="KRN00_001285"
     CDS             complement(43586..43840)
                     /locus_tag="KRN00_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827152.1"
                     /translation="MENKDFKLTVCIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            complement(44104..44385)
                     /locus_tag="KRN00_001286"
     CDS             complement(44104..44385)
                     /locus_tag="KRN00_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827153.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
BASE COUNT        14960 a         7157 c         4614 g        17750 t
ORIGIN      
        1 aaaatataaa taataattag cttattgtta actaaattat ggaaatatac ttaattgaaa
       61 acttaaattt atttccttgt attatcaaga tttcatgctt accatttcca atatcatgct
      121 caccaacttt tgatgtgcat aaactatttc aagtaaaaat gcacaaccta tcctttttga
      181 taagaaaaag cagtcaatca taaatatcaa ctgcttttat gtactgaata tcaagttata
      241 gaaaagctgg aatttatttt gagggttttt ctttctcctt aactaaattg ctttcaaaag
      301 taacctttac aactgcatga tttattttaa ttccagtaaa gcatatagca tactctttct
      361 ctttttgtat attagaaaga gaaattgtga atgtatcatt attaacgctt ccatgccatg
      421 tattactcca taaagtttca tctgttttat tgtcctttat ttccacaata ccactatctc
      481 catccatttt aaaagaaatc tctgtgtcta aaacatctat atcattagac acacgaaaca
      541 aacgtgcatt aacaaatggg tctgaagtat cataattttt atctaagtcc atttcaatgg
      601 ttgtttgtcc tgattctttg ttgtttaaat tattatattt actttcattg ctttttttac
      661 aagctgtcaa gctaaccaca ctaatgatac taattaaaat aataactaat tttttcatag
      721 aatttatctc ccttacaatt tctaattttt aaccctacaa actatagtat taaactaatc
      781 tactatttta catcaaattt ttcaatcatt cagcctttat cttttctcat tttaattgca
      841 aatatgttaa ataattttgg aattttaatt attgtagtat cttaaattgg tttataacat
      901 attatgaaaa tttaagagtc aagtcactta tttaaaaata cacaaaatta tactttattg
      961 tataaaaaaa gagattataa tttatacaag taaaataaac tttattattt tactcttcta
     1021 tataacctct tttctatata tctattcaaa taatttagct cctaaactca caaacatttg
     1081 taaaatcaaa aatgcttttg tgtctatctt atgattactt tgtaaaatct cttttgcatc
     1141 ttcttgcgaa attaaaagcg cttcaatctc ttcatctggt tctaaaaatt catctgttat
     1201 atcaccatca catatacaat aaacaaaggc aacagattca tcactcattc caggagataa
     1261 ataaacttta tcaatacttt tatttttttt aatttctaaa agagtaagtc ctgtttcttc
     1321 tctaagttct ctttcaacgg aaatatctat agactctcct tcatcaacaa gacctgctgg
     1381 taactcgtat atatatccat taataggtac tctaaattgt cttattaaaa ttaatttttt
     1441 actactttta tgaagcccaa ctattacaac tgcatctaca ctatcttctt cattcttcaa
     1501 ataaatattt tttaattgct cactactttt tcttgatgct accatccaaa ccttatcttc
     1561 atctaatttg tttttatact ctatttcaaa aagtcctata aacttatttt caatcattgg
     1621 atttacattc tttattatag tttttttcaa atttactacg acctttcttt tttaatacct
     1681 ttttaacatt attaagtaaa tataatatct taacaaatat tcaacaactt attatatttc
     1741 catttcagga ttatctttat ctacaaaacc tactttaatt tcacaattaa atatttcctt
     1801 taacaatttt gctaattctt ctcttgcact cattacctta tctaaattag catcagtaaa
     1861 accatctata ggaaaaaata tattttttga gctattagta atttttcctt cttctccttg
     1921 tctccatatc catcttctag tttttaccat gtctccaact gaataaatta attctccttc
     1981 ttccattaat tcaacatcag tttctccaaa tggtacaaat ttatcccctt ttttagaaaa
     2041 tctaacatat acatcatcat ttctaaaatc catatcatga gcacccattg gaagtaaata
     2101 ttttaaagaa atagagtttc ctaaatctac aataggattt atatgaggaa gtttcttatt
     2161 cttagcaacc cttgttgtca ttgcttctat cgaactcata aatttatttg ggttcatgcc
     2221 tagacttcta aatgcctctc tatatggtat aatttcttct gattccttta cttttttatc
     2281 tttgaagtaa tcttctactc tatctatact tatatctaaa aggttgctta ttctttctat
     2341 ttctttagta ttatctattc cttttgcaac tactacacca aagcatacat tttctaattt
     2401 atcaaaaact tctttttcta ctataaattt cattttgctt tatcctcctg ttattttaca
     2461 ttattttcta aatagatttt atcactttgt gtcttataaa tataccccct atttgctaat
     2521 tgtttaattt ttttaaattt tccaattaat atcaaatatt ttatatgtac taattacaaa
     2581 tttaactttc caaaacaaat atcttgtttt ataatgtata atatattttt atggaggcaa
     2641 gactgtgaaa aattttattc taatatattt tatagtgatt aattctattg ctttcttttc
     2701 aatgtacata gataagaaaa gagcaattag aaacgaatgg agaataaaag aagctactct
     2761 tatgtctata gcagtaattg gaggtagtat aggttctata attggaatgt attcttttag
     2821 acataaaact aaacacatta aatttacatt tggtatacca tttatactat ttttacaatt
     2881 tttattagta tatttttata ttttaaagta attgaaatat aaaaccttat tcttttcaat
     2941 aaattaaggt gtataaaatt aaaaatttta tacacctttt tctagcaatt attaaaaaga
     3001 tatttaatta aaattaatga cccttatgtt tagcttttct cttttcttgt ttcaaattaa
     3061 atagtctttc tttttcttct tcttttctat ttttagctag gttttttcta tcctgttttc
     3121 tttcttcata ttgaagctta agagcatttt gagccttagt ccctatagtt tctttttctt
     3181 gttccttttt tacttttctc tgcattcttt tgtatccaat gttgtctttg gtcacatttt
     3241 tttctaattt aatgctacca aaatctaatg agaaaaatct ttcaagtata aattcataca
     3301 cttctacttc tttaggttct gctccaaaaa ctaccctaca tgcttcatat tttttaccat
     3361 cttgtctttc aaatatacct acccaaaatg gttcttcaaa taagactgtt aattttccac
     3421 taattttgtc cattgctagt tcctccttaa attactttct aaagaacgga caaccaagga
     3481 ggcaggttac tgacagctat tgctgcgtct ggactaccaa ccagactgtg tttttatctt
     3541 tatagattaa atattatctt ttttaatcat gcttgtcaat cttagtatca acatctatca
     3601 tattgattta agtgaaatca agctttttaa ctctacttta ttattgttaa cactaagaaa
     3661 attaattatt tttcataata aattagttat tatacttatt taaatatcaa tctttattgt
     3721 tccctgcata aacaagactg cttcaccaga aatttttaca gtattatcct tcaacacttc
     3781 acactgaatt ataccaccac gattagaaag ttgagcagct accattttgt gttttcccaa
     3841 cttttcagac cagtatggaa taagattaca atgtgatgaa ccagtaacag ggtcttctga
     3901 atctaattct ggacaaaaat atcttgatac aaaatctgta ttacttcctt gtgctgtgat
     3961 tattatacct aaccagtctg tcaatttacg caattgtgcg taattaggtt tataatttat
     4021 aacttcttgt tcactgttta gcaataagat taaatctctt gaagaataaa cagcacttgg
     4081 tacacagcct atcaaattag cttgttgtgg tgataactct atttcaatag gcattatttc
     4141 tggaaatatc atttcatata gatttccatt tcgtgtaact tcaagctttc cactttgagt
     4201 aaagaaatct atccttttta cattaacatc aataaaattt gatattacat aagctgctgc
     4261 taaagttgca tgaccacata aatcaatttc tgctttagga gtaaaccatc gtaattcata
     4321 atttccttta tctttaacta caaatgctgt ttctggtaaa ttgttttctt ctgctatttt
     4381 ctgcattaac tctaaaggta ttcttctgtc aagaacacaa actccagcag gatttccttt
     4441 aaatagttta gttgcaaatg aatcaactat gtagtattcc attatttaac ctctctttct
     4501 aatataaaat atacatcaat ttacattcaa taaaacttta aatttcttac atatattttt
     4561 taatattact ctgttcaaca acttttttac ctaacaatgt aattgctttt ttggcacaat
     4621 tatttacaca acgataacac attgtacatt gcccatttgc aacaatcata caatttttaa
     4681 ttactagatt cttcattgga cataaattaa cacatttacc acatacaata catttctcag
     4741 tattaatttt tagtttatct gtatacatat ttgttttatt gataaaatac aatcgttgtc
     4801 caaataaccc tacaatatga ctcaaaaaac ccaacccttc ttttggtggt gacccatgtt
     4861 tcagtttttt agcagcctta gttactttct tttctgcttt tattacaagc tttctattat
     4921 actctaaaga atgttttaat accttttcat ctcctatact atctggcatc ttcacatgta
     4981 atccaccaac agttatagca ccgtattttt ttaatattct agataacaca ccagagccat
     5041 ctccactaaa tagagccata gttgcaataa taaaaacacg tttaccattc cacaaagttg
     5101 aatgatttat tataaaatct ttcaatattt ttggcacatt actatattgc acaggataac
     5161 taaaaataat attctcatga ttattgatgt gctgtaaaag ttcattatct tcaatagaat
     5221 aagaacttgc tgttatatca tattcttgta aaaatttttc tacacagtat cttgaatttc
     5281 ctgttccact aaaatatatt cctatcatag taattctcct aatagctaag attatatagc
     5341 tctattctta aaattctgac tttttatatt atctaaatta agtagtttat ttaaataata
     5401 taaacttaat tcaacaagtt acctactgaa cctcccatga ctaaagtcat agggttcctg
     5461 cttgatagaa ttttgcataa tcaatttact aaatacttgt ctaattcttt ttttatcatt
     5521 ttaaatatac attttaataa tattaataag ctatacttcc ttaagcatat attttcccta
     5581 aagtaaaact attgatgatt attacattat ataacctaat tataaattta gtaagttcat
     5641 cacatactat acccttaatt ctcaattata aagttcccta aaaaatattt gaaaatttaa
     5701 ctataaaaaa attccctatt gcctaatatg tataagtaag gagtactata tagtactcct
     5761 tatattgtac tcttataaca ttgatgcctt aatattattt taatcttaat cattattgat
     5821 ttgatttaaa attataaata ggttccaata ttttaattat gtcaactata tctcttatag
     5881 ttttaataat ctcatcaatt ggtttatgtg cttgttgcac tttatcaata gtattaatta
     5941 aatccattta cacatctagc acctgtatgg caatttagca ttatccttat cttatacttt
     6001 gttgtaaatt cttgattaca taattctatt atctaactta tagctgtgca atctacatta
     6061 tctgtaaata tctttgcttt atatattttc cctgaacctc taacattaat ataacagcct
     6121 ttttgctata cacttttaac tatatactta attttaataa cattacttgt ttataaaaat
     6181 atactataga taaatttcac ataaaaataa taattcaagt attgattttt atataagcaa
     6241 atttgtaatg tactaaaaat aacataaaag tttccatttt tcaatatgta agcttttatt
     6301 atgttatttt attgttaaag gtttcaagtt tttatttatt cattaaaaaa aaattattat
     6361 ttttgtaaaa ctaatcctat agtcatacta tcgtcagaat atgcttcacc cttaacatta
     6421 ctaaaaaact caacagactt aaatccaata ttttcaactt ctaataagaa actttctttt
     6481 gaaaaatagt gattccaaac ataaaacaca ttttcatctt tttcggttat tacaagagtt
     6541 tgttctaatg tattataatc attgtattta caattatctt gtagacacat atatttttca
     6601 ttactccaaa atcctccatc ttcatttatt tcccaatatt taatttcctc aaaattattg
     6661 tatttattta ttgtaaatac atctaatatt aattttcctc caggttttaa actatcataa
     6721 attttttcca ttaataacct tctattttca gttgacaaag ctccataatc acaataaatt
     6781 aaagtagcca aatcaaattc ctcattatag ttcatattta aataactttg aaacaagtaa
     6841 tttatgttta aattagtctc cttatttcta ttttgtgcat agttaataga acgttttgag
     6901 aaatcaattc cagttacctt ataacctttt tgtgcaaatt tctctgcata taaacctgga
     6961 ccacaaccta aatcaagtaa tttaggataa ttagctggat ttgcaactgt aactatccaa
     7021 tttacagaat cctcgataaa gttaaaattt ctacttgctc cttcaaaatt agtgtctaag
     7081 tgtgctttta ataattgctt tgaaatatac tcatcatccc aaaaattaat ttcactttgt
     7141 ttataaagct ctggtctttc taaatacata cataatttgt ttaacaaaac ataccactcc
     7201 ttaaaattta tttttaaaat aaaaaaacca cagagtttac tctgtggttt aacttcaaaa
     7261 agatgagttt aaataagagt aaaatagaac caaatatttt taagcacaac aataaaacta
     7321 cagctttact ttgtttgctt attaaatttg attttattca ctcttttcca gcaatactta
     7381 tatcaacgat tttatgatat caaatatcac cgaacaacat catcctttca tatttttatt
     7441 ttatgaatta attatatatt taaattttat atttgtcaat aaattttaat tttaataaat
     7501 tttaatcatc atagtaaaaa aaattttttt atataaaact aatcaaaaaa agatatctgt
     7561 acatctcctg agttttttaa cttttccttc attattttag agtaactgct tgatagagaa
     7621 tatttatatc taagttcatt aaccatttta tacaattgat ttttatactc cctattaagt
     7681 gaacctgcac tatatagtat tgataattta tcaagtaatt caggaaactc ttttttaaca
     7741 aagtcaaaaa aaacacctct agttataccc cttaagtata aagtcccagg taaaacataa
     7801 tgtacattac attcttttgc atgtctaaat agcgaattta tattatcaaa atcatctgta
     7861 atatatggta taattggcat aatatgtaga ccaactgatg cgttagtttt tctaaattct
     7921 tttaacattt taaatcgtct cattgaatcc acaccatttg gctcaataag cctttgtgta
     7981 tcttcattta ctgtggtaat tgtagatgct acattgatat atgtaatcct agatagctta
     8041 tcaattaaat cgtaatctct taaaattaaa tctgattttg tagaaataat agctggtgtc
     8101 ttgtatttta tcagcaggtt taatatttct ggcataattt tatagtcagc ttctattggt
     8161 tgataactat ctgtaactcc tcctatattg attacttctt tcttccattt actgctttta
     8221 agttgtctct caagtttttc tactatattt gtttttacat aaatctcttc aaaataatta
     8281 ttggagttga tgtacttatg agagtaaata gcataacaat atttacatcc atgctcacat
     8341 ccacgataaa tatttaaatc ccatttatat ggcatactcc tttttaattt attacaagct
     8401 atttcacaat ttattggaat atattttatt ttattataca aataatcacc tctttatata
     8461 caataatact ataatgttaa tctatagtaa ttaaaacatg atatttccag accacaattc
     8521 ataagcttta ctatatttac aaagtaatat attccattca tttattggta ttcctccaca
     8581 tgttgctttt tcttctaaat tatataagca ttgctttaaa tacattttat tatgccaatc
     8641 atcatataaa ttttctaaat ttaaactatg ttcattagat atatcatttg caaaatttct
     8701 atttttccat tttaatatac ttgtatattt aagttcatta ggtttataat ttctttttaa
     8761 catttcatca tgtacaattt ttgtataaaa tttaaattca tctatactat aattcaatac
     8821 tttattcact aatagatggt ttggagtacc ttttttatct atagaacctt ttatagcaag
     8881 tagctctctc cattgactta ctaattgatt tttaggtaat acatcaatta aatccttatg
     8941 ccataatctc ataatttaac tccttactat aaaatatttt ataaattcaa taaccaatct
     9001 atcttacaat tttacatgtt caataatttt atctgtaaaa actataccat ttaaatggtc
     9061 tatctcatga caaagacatt ttgccataaa acctgaacct ttaatttcta ttttctcacc
     9121 gtattcgttt agagcttgca ctgtaacttt ttttggtctt tttaatttac cccatacttc
     9181 aggaaaactt aaacatcctt caacaacaat ttgttcccct tcttgtttaa taatttcagg
     9241 attaacaagc ttaataagtc cttctcctaa atctataaca actaatcgct ttaatactcc
     9301 tacttggcat gcagctaatc ctcctccatt tggagtattg tacatggtct ctgccatgtc
     9361 atttaatatt tctcttatct tattatctac gttttctaca tacttactct tttttcttaa
     9421 aatttcatca tcaaatgttc ttatctttct tatagccata atattctccc ctacttatct
     9481 gtgctcttga ttttctttca ctttcttcaa ataaaaatac actttcaatt ggttcattaa
     9541 aaattcttga aatatcatat gccaaccata ttgaaggttc atttttacca gtttctatag
     9601 catttatagc ctgtctagat gttccaacta atcttcctag ttgttcttgt gtcaatccta
     9661 atttttctct taatatcttt attttatttt tcatatttgc tccattcatg taaggttaac
     9721 tttacatctt aaatgtaaca tttttcaaca ttactgtcaa gtcaacctta catttatata
     9781 ttaaattttc ttatttaact atttttttac taaacttttt aaataataat aaaatccata
     9841 ttaatgatat aacaattgaa ataaacatat agacataatt atcttcctta aatgccttcg
     9901 atatccaaaa agttggtaag aagaacagaa tatattgtgc tttatttaaa ataaaaaatg
     9961 gtgctaaaat acccatcata aaaacacctg agaatttcgt aattaccatt ccttctagtt
    10021 tatttgatga taaagaaatc actaatattg atataataac tccttgtaat aaaactaata
    10081 aagaaattga taagtttaac aagagagaaa ttttagttag agaaaaaaag ataagtagaa
    10141 tcatagtaat aataaatgct aagatacctg gtattccaaa tcgtgaaata agataaccag
    10201 ttttaccaag cggagttact attaaatatc ttgaaatgct gtcatcaatt tctcccaata
    10261 tgaccattgt agaagcaaaa aagaacataa aaggtgtaat aaaagctaaa agtaaatcaa
    10321 acatcaagaa atacggctct aaatttaatt gataataaaa cttgttaagt gatatattct
    10381 gtattaatgg tattccaaat tttataaata ctccacataa tattggagaa acacatacta
    10441 taaaaagcat agcatctctc ttaatttgtt caaactcttg tttaaacgca tttataatct
    10501 ttatcatagt tttactccac ctaccttttt ccaactgcta caaataaaat aataagttat
    10561 aaaataaatt attattataa ttgatattaa aattaaaata ttaatcatta taaaattttt
    10621 atctccacta ataagagaaa tacatatatt aaaagggtac aaatttgcat atgattttgt
    10681 gtcaagaagt acattcagta ttggtggaat aaagcatata atctcaatag gaatacttaa
    10741 aacaataaac tgattcaaac tagatgcttt acttgcaatt atcaatccaa gcaaagaaaa
    10801 tataatagaa gaaaaaaagg tacctatagt tgatattata atattatcta aatttaatgt
    10861 aatagcaata aacatagcta caatactaga tattactcct aatgaaatta cctttgataa
    10921 aatatactca gatactttta ctggagatac agctaaggaa tttaaaaccc tttgactttt
    10981 ctcaagaagt acaatagctc ccataaaaaa caatcccatt gctgctgggt cagaataaat
    11041 cataattata gctatttttt ctctcataaa agttggaaat acattgataa tacaaatata
    11101 tataatactt aaaaaaagat ataaaaaata aaaaccatac ttaaattgaa actttatatc
    11161 tcctaaaata agatttttta gcctcattgt aaattcctcc ctgttatctc aataaaaata
    11221 tcatttaatg ttggttcact actatgtatt gataaaagtt tatttttctc aataagcata
    11281 ttcaaatttt tatcattagc agtattgttc agaaaacatt cagaagtttt ttctccatta
    11341 tcaaagtaag tatatctaac tttaatagct ccttttgaca taataagatt atgtggtgta
    11401 tctaaagcag atattttacc atttacaatg aacgctactc tgtcacaaag ctctgttgca
    11461 tctaacatgt tatgagttgt taaaataata gttttacctt tcgatttttc tgataaaatt
    11521 atatctttca taaccttgct atttgacggg tcaagaccac ttgttggttc atctaaaaat
    11581 aaaatatctg gattatgtaa taaagctttt ataaaattta atcgagattt catacctttt
    11641 gaatactcag ataccctttt atttgcttca ttttctagtc ctactgattt taataactca
    11701 tcaatagata gtagtttttt agaatataga gacccaaaat attttaaatt ttctattgca
    11761 gtcaactttt catataaact aggaaattca aaatcaactc ctatattttc ataaaattta
    11821 tttgagtgtc ttttactctc tactccattt acaatgacac ttcctccata attagttatc
    11881 attccaatta gaatcttttg taatgtagat tttcctgcac ctgatggtcc taaaaatcct
    11941 agtatttccc cttttcctac ttcaaagtta atattttgta aaaaatctct atctgtataa
    12001 ctaaatgata aatcatcaac tttaatcatt caatatcacc ctttcaaatt tttgactatt
    12061 ttgactatat ggtcaataaa atataatttt tttgtttgtt aataattttt aataaaagtt
    12121 attagcaaac aaaatttaaa ttctattcca taagttgtat aactaatccg tttatcatta
    12181 atcttaaagc atcttcaaaa caattacttc caacctcgcg cttatatagc atggtaagaa
    12241 aaactgctct aaatgctcca ctaaagcttt ctatgtcttt attttttgca tttggtatgc
    12301 aagatataat ctctccaatt tcaaagtcat catgtctaaa gtgttcttca attatagaat
    12361 ctggtaactt tctcaccaat atctcaaatt ctccatttat catgagattt aaaattgaag
    12421 tactatcaac catcctatag aatttcataa atatatctgt caattgttca catgtaatac
    12481 tttcatctac tctatttatc tcatataaga tttctttttg tatagagtca tgtatatctc
    12541 ttaatacctc aaaaaagagc aattcttttg attgaaaaaa tagataaaaa gttccttttg
    12601 gtatttttac ccgttttaca agctcatcaa cagtagtttt tctaatacca tattgctcca
    12661 tacacaatct tgcttcttct ttaagtcttt ttattatata ctctctttct ttatcagaat
    12721 atgatttagg catctttttc ctccagtttg actaaaataa tttatatagt caatataata
    12781 ctttttctat ctaatgtcaa tagtattatc agtatattta aaaataagct taaaaacttt
    12841 cgaaaattct gaattttata tagcattttt tattatctag tgttataatt aagatataaa
    12901 taatatatta ttctaatttt catatctatt tgcttatttt ttaacttagt ttctaataga
    12961 agtaatcata tttatctttt taaaagtttc aactttaata aaaaataaag gagttgattt
    13021 tatggctact actacaaaaa accgttttta cgattatgtt caagaaaact taaataaata
    13081 tgttgaagta cattcttact ttagcagttg tcctctatat ggtgaaatta tagaagcaga
    13141 tagcttatca attacacttt gctcaagata tatagatgaa tctaatccaa ctttaaatga
    13201 aacttacaca ttatatttac cattaagttc aataatatct attagaacac tataaaaagt
    13261 taattaaata tgggttattt atatataaaa tgtaagattt tctatatttc tatataaagt
    13321 aacccttttt tatgttttta aacttatact acataaattt aaagctgaaa acaaaacttt
    13381 acaatcattg attatcttat ttatcaataa tttaaagtaa ttattttcag cttttattaa
    13441 gacaagttac taatacacac taatatatgt taatacttaa gtactctatt tagcactttt
    13501 taattttact aactctttaa atgcattttt atttgctcct ccaccaactt gagttacttt
    13561 ttctaaagtc ttatttttaa gaacttcttt ttggctatca gctaatttat caccaactaa
    13621 aattactggt gacccagttt ttgctcctaa aggaccaact gccaatccat ctattaaatc
    13681 attttgattc ttgattccat ttttaactac aaatgcattt tttaaagtat cttttttata
    13741 aaaattatct attatctttg aattagtttc gtctctacta ctaccagata atctagttgg
    13801 attttttaac ttactttcta gattgtttga tagggatgct gttcctccaa taatataaga
    13861 tttctctata tttaatgaat ttagaaattc atcagctcct tgcaattcgc tcttttcatt
    13921 tgcaagtatg attggtatgt tattttctgc tgctgcagcg cctacactaa ttgcatcagc
    13981 taatcctttc actccattta caactgctat ttgagataca atttttatac catttaactt
    14041 ttgagctaat aataaacttg tcttgtatct atcacttcct gatattctct ctatcgatat
    14101 atttaagctt tttaattgtt gttcaatttc tttacttata gaattttctc cacctattag
    14161 gtatactttc ttagcaccta atctctgtat ctcagcttta gtttttgaat ttaaagcttc
    14221 tttttgtgtc aataatattg gtgaatttat agcagatgta aaaggagttg ctgccaatgc
    14281 atctactatt gaactgccat ttactaaaac tacattttct gaagaattga aaccattttg
    14341 actaactttg atagcagttt catatctatc actaccaatt aaagactcat ttgggatact
    14401 ctcaccagaa gacttttctg taacagcttt tatagtaaaa ttacacggat agaagttact
    14461 atctctattt atatcaaaga attttccagt attatctatg atataacttt cacctaaatt
    14521 agcttttgct ttaaatgtat catatcctgg tacatttgac tcagaaccta tagttgactc
    14581 tccatttttc ccctctatac tgactacaat tgcacccttt ccttctggta tatcaaaaga
    14641 atcaattgga actgttatgt atcctgaata ttgggcagta ccttctttta attttttcat
    14701 attgttttct tgaggtatac catttactac tggagcataa tatacttcat acttagctcc
    14761 tatactttca gttaagaaca ttacagattt tagagtttca tcgcctctat tgaaatcaaa
    14821 tacatttgca gctgttatct tttttgaaat taaaggtaca atacttgcat agtcatgttg
    14881 atacatcttc tcatcatcat ttggtttttt accacctttg attgaaaaat tatctatatc
    14941 agacataagt gtcttgtctt cataagatat ccagaaatat ccaccctcag aattataatc
    15001 tccccagcta ttttttatta accaagcacc attttttgat ggtctaatat ttgcattaaa
    15061 attatcttta gaatagttat catcccaacc tacaattgaa atagcatgat ttgtattaaa
    15121 actttttgtt ggacaataat atgaattttg gtcatcactt tgatatttaa tatcttcata
    15181 ataaccagat gttacagctc catactgtaa tatagcattt tttgtagaat ttatgtcatt
    15241 gcttacacac acagcatctg tcacattaaa aacagtaggt gctgtattca tattagttgg
    15301 tttttttgct ccttgtgctt tagatactct accattgtat gggatatctt tttctaattt
    15361 aggacctgac caagatgtta aatatcccat agcttcataa tttaaagcac cattcatatc
    15421 atttacagac catccatatt caccatctga agcccaccat cttaagtgtt cttctgataa
    15481 atcatagtct ccataattat ttaactttaa gaaactttct aaggttgcca ttgcagcaaa
    15541 atcccaacag attcctaaat cctcttgatt ttttattgat gtcataagac ctaattttct
    15601 agggtcataa gatgttggag ctgttcttcc tttactttgg atttgagtac cttccaactg
    15661 atatggattt ggtataatcc cattatattt ttctgtacgt ccatttttag catcatttag
    15721 atattgttta tacgtctcac tgtattctgc tttttttatc tgattcaatg tattgctatt
    15781 gtcagctgat acaggaattg ttgacattac taaaatagat attaaaaaca gcgcaacaaa
    15841 ccttgttact ttttttgaag taaatttttt cacgctttct cccccttatt ttgagctaat
    15901 tttttaaatt ataatgttat atatgactaa atatcaagta tttacaaata tacaatcatt
    15961 taaatcaatt ataccaaagt tttcctttat aaataaataa aataaaataa aaaactgaat
    16021 ttatttataa taaattcagc ttctcatttt ctttttatat gtttttatct aaatcctatt
    16081 acagcagctc ctaaagctcc tattatttga gtatcttctg caataaaaat ttttttaccc
    16141 agtatttctt ctatcatttt tactagttct ttactttttg caagccctcc agtaaatgca
    16201 acttcatcta ttacctcacc tcttgctaac attgaggtgg atttatttgc aatagattta
    16261 agtatccctg ctgccacctc tccagtagaa atgttttgag ctagaagact tacaatttca
    16321 gactcagcaa aaactgtaca catactagat atattaactg gttcatatcc tttggctaat
    16381 gtatctatac tttcaatatc gcttcctaaa aggttagaag taatctctaa aaatcgacca
    16441 gttcctgcag cacacttatc attcattata aagttaaata catttccatc tctatctaaa
    16501 tttataactt tactatcttg accacctaca tctaaaatag tccttatgtt attgtttaaa
    16561 aagtaaatac ctctagtatg acaagttatt tctgttactt tcttatcagc aaaatccatt
    16621 actccccttc cataacctgt acctaccacc ttttttatat cttttttgtc aatttcacta
    16681 cttagcaact catagacctg tttagatgta cttttagggc tccatccagt tggtataatt
    16741 attttcttaa taattttttc accatcaaat agcacaccct ttgttgccac tgaccctgag
    16801 tcaactccta tactaaacat agttcctcct acttttattt attcctacaa catctctaca
    16861 aacgcttcaa atctagttct taattgttca gtatctgatt ttgaataatc agtttcaaga
    16921 gacataaatg gcttattttt ttcttttgta acaaattctc ttattctata actttctata
    16981 ttaaatgtat gacatgcttg taaaactaca tctattacag catctacatt atattcatct
    17041 attattctat ctaataattc aatacgattg tcattattca tcatacaaga acaacctata
    17101 tttatatatt tttgtgttaa agcatcatat acatcttcta tttcttcatc aaccaataaa
    17161 tcgtttgatc taatggctcc acaaagttca tatgcaacga ctgatgcccc tgcatcttct
    17221 aaagttttaa ctattttttc gcttattcca ccaataggag aacctgttat caatattctt
    17281 ggcttatctt tttgaacagg acattcacct ttttcatatc tttctttcat atcatctata
    17341 acttttctta aagaatgttt aagttctgca cggtcaaatt taaaacctgc ttgatataaa
    17401 acattatgta actcaaggcc tgtaagtgca gatggttgta atttaccaag tgcataaaac
    17461 tcttttaaaa gttctctttc ttcattttta tcttttatag cagttcttat atcttcttca
    17521 gttatagtta cacctaaaga tttctcaacc tcttctttta atcttatcat ttcatctttc
    17581 caaagtttat aggcaaattc tccttttgaa gtatttggca aatgcattac atatgttggc
    17641 ttaacttttg caagttcttc atacattttt ttcttaccat cacaagtggt ttctcctatc
    17701 aacaaatcag aaaaatagaa ataaggacag gtatctgtta ttgcatgtcc atagcttgat
    17761 ttaattaaag gacaaagatt tcttggaagc accctttctg catcaggtat tggctcttca
    17821 ctaacgccgc atacacctac tacagttgct ccagctgcca ttggaatttc aactggagta
    17881 aatgtacaga aaactccaac catctttttc ccactttcct taagttcctt tgcatttata
    17941 aatccttttt gtctagcttc attgaagcta tcaaattgtt ttggcaaatt tgtcatgaaa
    18001 atattcctcc caattacttc tcttcataat tcaatctctt cgtaattcaa tttgtatctt
    18061 aagcaataaa aactaaattt ttccattaaa atacaaacct ctacattaga ttctatcatg
    18121 ctttaccttt tatccataat tgtttttatc aatgcaaaat tagatacata tagatatatt
    18181 gtataactaa ttttttatgt tataattttt cttataactt aagctctcga atcctcaatc
    18241 tataagcaga cacagcagtt tcacataatt tatcaattaa ttttccattc acataaaatc
    18301 ctacaaatgc tcctattcca ggcattagtt gtaaaaactt agctaaatct aaataatccc
    18361 tatactcttg ttgaaatgtt ctccaatcaa aatcattgat gtcttctggt agactattta
    18421 catattcatc ccagttattc atcaatttaa aagttttgtt tatatgctgt tgactagaaa
    18481 aagccaactg taatatattt aatatataaa tcctttctct ataatcttta acatcatatc
    18541 catatattga agctacatca tataaaaatt tcactttaat gcctaaaagc aaaggaaaat
    18601 cagataaacc taagaggatt cctcctgccc ctgttcctgc cccttcaatc attgctgtag
    18661 tcttgtaagt tttagctttt tctaaaacta atttttctct ttcttctaat gacatatttc
    18721 taagtggtgg ctttgtagca tatttatatc caaacagtac ggtttttgtc attactctta
    18781 tagaagaagt aattatttca tgatatttat ctggcaatac tccattaaat ttattctgta
    18841 taccctttga tgctttgtca aatatagaag gtttctttaa tatatttttc ttccattctt
    18901 caagttcttt tttgactagt ttaatataaa caacatcttc ataatctttc acattttttc
    18961 tcctaataca atgtattttt gtcaatttaa tagcttaatt taaagtttaa atatttttat
    19021 ctattaaatt aaactattca aatactcttt agtttcttta tctgcaaaac tagcttctac
    19081 tgcatttcta taaattattt tatagtcttc taatcctagt ttaaaagtat caaatataac
    19141 atttagttct gaacttaaat ttatatctga tacagttcta ttatcagtat ttatacttac
    19201 atgtaaatta tctttataaa aagtataaaa tggatgtacc tcataagaat ctactgtctt
    19261 agtttgtaca ttactagttg gacataattc aagcaatatt tttttatctt taactaaatt
    19321 atacgccttt tcatggtctt taatttttac cccatgacca atcctatccg cctttaaaat
    19381 atttatagca tccaatacat tttctccact tgcagcttct cctgcatgta ttgtaacttt
    19441 atatccatat tctcttgcta atttaaaaac atctttatat tccttacaaa atccctcttt
    19501 ctctggacca cacaagtcta ctgctacaac acctttattt acaaatgatt tcccttcttc
    19561 aattactaat aatgcctctt ttgaggtcat tgttctcata caacctaata ttaaattgcc
    19621 ttttatatca taaatacttt cagcttctct aattccttca attataccct caattatatt
    19681 tttaacactc ataccttttt gggtgtgaag taatggtgca aatctaattt caatatattt
    19741 tacattttct ctacttgcat cttccaaaag ttcaaaagta attcttttta aattttcctt
    19801 agattgcatt acttttaagg gtaaatcaaa tttttctaaa tattcatcta gtgaagtaca
    19861 attaaaagaa acctttgcta atttttttat ttcatccata ttatttgaag gtaaatctat
    19921 tttctcttta atagctatat caagcatggt ttctactcta acacttccat ctaagtggca
    19981 atgtaaatct atcttaggta aattttcaaa cattttatcc tcctactgta cttataaata
    20041 atactatcaa cagattttta agtcttattt ctattatatc aatatactac ggtttttaat
    20101 tctaaaaaag tcatatctca ttaaaatatt ttaatttaat ttatgactat ctaattatat
    20161 ctactgattc tttttaatat acatttatta atatacattt gataataaaa tttcaataca
    20221 taagaattta agttatataa ttaaaacttt gaattacaaa ggaggactta ttttgattac
    20281 cttaagtttt gatatagtgc aaaccttgac actatctata ttcttctttt taattggtaa
    20341 tttattgaag aataaagtta actttttaaa taatttctgt atacctgcac cagtaatagg
    20401 aggtctatta ttttgttttc taaatttatt ttttaaatat tttaatatag cagatatatc
    20461 tataagtgga aatttaatgc caaattttat aactttcttt tttacaacta taggactcga
    20521 aataagcata aatcttataa agaaaggggg tagtgtatta tttagatatt ggattttgtg
    20581 tggagtattg gcattttgtc aaaatatatt agctattaca atatcaaaga ttataaaact
    20641 tgaacctctt ttagggctta tgtgtggaaa tgtatctatg gaaggtggtc atggttattc
    20701 tgctgcattt ggacttacaa tagaaaatct cggtatagaa ggagcagttg gggttggatt
    20761 atctgctgca acaataggac ttattatggg tggtatattg ggatgtcctg tagctaaatt
    20821 tctaataaat aaatataaat taaaaccatc atcaaatata gacttgtcga ttcctagata
    20881 taatagaaat ctaaagagat ttggaagtaa attttttaga aataagaata ggataaaaaa
    20941 taataacttc tccgaaacaa taacaccatc tgtatttttg gaacaggttc ttctcatatt
    21001 tatttgtata aatacaggag aaattataag tagatgcttc tatataacgt ttaatatact
    21061 attaccctct gttgtaactt gtatgttttc ggctgttatc tttagaaatt taaatgataa
    21121 gataaatata ctagaattaa attttaaact tatagatttt ttaaaagaac tttcattggg
    21181 aattttttta actttatcac ttatgaatat agatttattt gaattatcta cattattacc
    21241 tcctattctc ttaatagtaa cttttcaagt aatctttata atcctatttt caatatttat
    21301 ttgctttaga gtacttggaa aagattttga ttctgccatc ataataagtg gtttgattgg
    21361 acatggaata ggagctactc cgaacgcttt ggcaaatatg agttctttga cacaaaaata
    21421 tggtgattct ccaaaagcct ttttggttgt accattagta agtggttttt tgctagatgc
    21481 tattagtatc ccatgtatac tattttttat aaacatacta acttagtatg tttatttttt
    21541 gttatatatt gacaatttgc tctttttgtt atatattata aatataaagt ttgataatga
    21601 ttttcattag gaggtgttaa taatgactgt ttacaactta aaacttggac aaaagggaat
    21661 tatagacaat atagctggaa atgaaaaact tatgaagaga cttctagcct taggactaat
    21721 agatggtact gaagttgaag tgaaaaagat agctcctctt aatgacccta tagtgattag
    21781 atttagaggg tttgacttag ctattagaaa atctgatgca aaaaatataa atttaaaaaa
    21841 taattaatat ataataaaaa agagatttta aatctatttt caggccatca acattctatg
    21901 tgttgatggc tttttaaatt caatcatgtt gtaatacaga taatcaacag ttagataatg
    21961 tacagtataa aaaatttata ttaatttgtg tagatatagt tatgttattg actcatattt
    22021 actttaatgg acagttcaaa caaacgatag aactgtataa gcaagcattt aatgctactg
    22081 ttaaaacatt gattgaagat tcatgttatc tgcttattgt tcataatgaa atagtcattc
    22141 ataataagtt cttaatttta aacgattttg gaaacaaaaa tggtgtttca atatcagaag
    22201 ggtatcagcc aacagataaa attcaaacgg cttcttgatt ttattaaatc aaaaagccat
    22261 aagtcaacaa tctaaaaaga gattttaaaa tctctttttt tgtttatata tagataaatt
    22321 tgaataagta tttaaacatt atatactatg taaaagttat caatatagac ttgtaaataa
    22381 tagttataaa accacatata aatgtgctaa ctgtaaataa atatgtgggt ctttaaaata
    22441 aagtgtgtat tcttctaaaa agtggtgata attaaaatat taactatttt tataaataaa
    22501 ctatataggt ctattaaatt ttacttttaa gtttttatca tcttggagaa cacgataagt
    22561 attatcccat tgttcgtcta cattgcttcg ttcaaaaaca tcatataatt gttttacatt
    22621 ttcattatta gaaggttctt tttttctctc taatagatta ttatttactt ctgaaacatt
    22681 attttcttct ttatttgttt tttttgcttt atttcctttt aactcttgaa ttttattttc
    22741 aatctcttcc atttcttttt ttaaagcttc tatttttaat ttggctgttt caccatcaat
    22801 acttttatca cttcttactt tctctatttc atcctgtaat gattttttct tttgttctaa
    22861 gccttgtacc tcactttgac agctatctaa accatttgta attggtgctt gaccatttat
    22921 atttccaact ttcattttag taacctcctc atttctatat atcaaacttt ctctattcaa
    22981 gtacataata tagcttacaa atactatttt caatgaaatt gttctcaaat actagcgcaa
    23041 tgtaatgaaa taactagcaa tacatttatt tgaaaatagt ctgatgtctt atctatactt
    23101 atagcccctt gatatttttt agcaatttct tttatattta aaagacctat acctgagcca
    23161 cttgtataat tatttattgg attatagcta ttttttattt ctatcataaa aaatccaccc
    23221 tctaacttag tggaaagctt taaataccta ttttgtttat ctacaactct acaagcttta
    23281 attgcattgt caatagcatt agcaaacact atacataggt caaaatcgtt catgttagtg
    23341 ctttggggta taattacttc acaatctacc tctatgccta attgttttgc tatacttaat
    23401 ttattgttga aaagagcatc aataacaata ttctgtgtat tacaagaaaa tgataggtca
    23461 cttgttactt tttcaagctt atttaaataa tcttgtgctt ttaaaatttg gtcttttttc
    23521 aacaatccat tgacaatagc taaatgatta ttaaaatcat gtctaaagga tatagtttgt
    23581 gataatcgtg atttcgcttc ttcaatatag tttttttgag catgaatctg ttgattcata
    23641 attgccctct ccttgtcatc ttcgagagct tgaattagtt tcttaaaggt aaatagagaa
    23701 aaaaatacac atatagttcc aattatagaa aaaagaaaag cttgaatttc ttcagttata
    23761 gaagtattta atagcagctt tacaatccca agacttgtat ctatatttat atttgaacta
    23821 tattcaaatg attgcataaa taatattata agcaacaatg gaatcatcaa aattgctata
    23881 tatttatcaa agttcatgac cttaatatta aactttttag aactatacca atatataaat
    23941 ccagctatta taatagtaat taaagaagat agtcccatat ttatatcaaa tttataaata
    24001 tctgtattta tatcactagt aaatatcaag taatttaatg gagctgtaaa tccatatact
    24061 aattgttcaa ttaaatatac taacaaagtt gatactatag ataaaacagt agattgtttt
    24121 attatgtact ttacaaataa aaaagtcata agaaaaaata gaatctgtga agaaaataaa
    24181 ttatataaat taaaatatgt atttataatg attaaaaaaa ttgaaattat cgaatataaa
    24241 ataaaacacc aaaattttga attaaaattt gtaaaattga ttagaaaata gtattgcact
    24301 attaccatta aaattctata tacaataaaa gagaagaaaa aactgtactt taaaaataaa
    24361 tcggaataaa ataaattaat catcttatat cctcctattt ttcatgaact caagcataac
    24421 ttttgaaaat atttgttgac gtagtctaga aacaggtatt ctatctccac tttccataac
    24481 tgcattacca ttttcatatc catatacata ttgtaaattg attatataac tacgatgaca
    24541 cctaaaaaaa tttgttggta aacttctctc taaattttca atagtctcat aataatctac
    24601 agtctctttc tttaaatgaa cataaatctt tctttttata acttcacaat ataaaatatc
    24661 agcaagtttt aatttccaat atgaataacc tttttgtatt gtgatataat tactttcatt
    24721 atcatcaagt tttgtaacta ttttatccaa agttttatat agtttctcat tagatagagg
    24781 ttttatcaga taatttatag catctacttc aaaagcatca aatacaaatt catttaaaac
    24841 tgtaacgaaa attataaagc actcattacc atatgacctt aattttctag ctgcctgcat
    24901 tccgttaatc tcttccatct gtatatctaa aaatacaata ttaaactttt catgattgca
    24961 tagtaaatct tctactttat taaaaagctc tatattatat aataaattct tctgcttcat
    25021 gtataattct atattttcct ttaaatgatt tagcatatag gattcatcat cacaaatggc
    25081 aattgaaatc aatatataca ccttctttct tatcattatt ctaattatta tataaagtta
    25141 attttttctg ttcaattaat ctggtttaat atgttgaata tttgttccaa aatgtaataa
    25201 tctcactttt catagtatat ctaatttgaa tttgtgtatc aatattataa taaactaatt
    25261 tatcactttt ataaatttaa tttaaaaata tgcaaatagt atgcaacttt cgaatttacc
    25321 taataaaaaa agatatcgta aaataatttt aaaaaattat tttttgatat ctttttttat
    25381 ttcagtgttg tgttgtattt ttattattca aatactgttt gttcttctat atcttctgtt
    25441 agtgcattta aagcttttaa aactatattc tttctaattt ttttactttc ctcttctcct
    25501 aacataggat ttccaagtgg atatggtatc cctactgctg gaacaattct attagctcct
    25561 attgtaagtg atattggtac tactgtacat atatgaacaa ctgctatacc agctctctca
    25621 atctctttta ccatcgttgc tccacaacga gtacaagtac ctcatgtaga agttaaaatt
    25681 acagcatcta catcatcttc taacaatttc ttagaaaact cttctccaaa tctcttagaa
    25741 ttgccaacac tcgttcctgt tcctgtagta gttataaaat aatctactaa ttctccaatt
    25801 acaccttctt tttcaagctc tctaactaca tctagtggta caactaaatt tggattttca
    25861 aggacatatg ctctgtcata ccccccatgt atagttgtaa attctttatt tgacatagaa
    25921 tccatatctg ttaaatcgta aattccatat ttagtagcac ttgaagattc aattttgtct
    25981 ggattatcaa ttggaactat ccctccagaa gttactaggg caagttttat cttagataaa
    26041 tctttaacag gtttcatagg tgtaactcta tcaaattcag gcattggata ctcagtttca
    26101 aagctttccc ctttcatctt tttaaccaac atatcaattg ctctttcaga ccctctaagt
    26161 tcatggaaga aattttttct tattcctctc attatatatc cttcctcttc aggaggtcct
    26221 atttcctcac ctctaaccaa tttaagacct agttttgtca ttattggaac tacctttcta
    26281 agacttgctg ctgaatttcc tgtagacact atatgcaaat ctaatttaaa catatctaca
    26341 cctggatttt ctttatacat gcctgtaatt acaggaatat ttaactcttc ttcaactgcc
    26401 ttacaaatag tcccacaagc tactccatat ctacctgcat taaatgctgg gcctgcaata
    26461 aataaatcag ggctttcttc ttttatcatt tttaaaagtt cttgagttgc actctcaata
    26521 ttttcaccaa aatacgtatc tccgcaaatt acagttgaga ttatctctgc atcatcatta
    26581 aattgactct gaaatgctat tccaggtcct actacaccag cccttttttc tggcgggata
    26641 tctgcttttt cctctccacc tataccagca aagaaattgt ttatataatg aaccactctg
    26701 attttactca tctcttaatc ctccaaatca ctttatagtt attacatcaa ttagaccaat
    26761 gattacatca acagaacttt atattcaaat acttatttaa taatatcttg ctgtcaaatg
    26821 attatagcca tttgctatag ttgatgctat tataatttgt agctctgcat ccatgcttcc
    26881 gtcttcattt aagcatcctt tatacccacc tatcatcatt tcaacataat ctaaagttcc
    26941 tataattttt tccattgctg ggaaatgaac cactagattt ccttgaccac aagaaacaac
    27001 tgcatctgct tccttagtag cgtctgctat agattgactc ttgccatctt ttccaggaaa
    27061 ttcgtccgtt atcaaaacta catttgctcc aacttcacta cattttttac aattcatcat
    27121 taggtcagta tctggattcc cataaccttc ttctgtcact aggactccat caacgcctaa
    27181 aaattctatt aatttagcta ccatatcaga gcttctctct ttatcgacca agaatacgtt
    27241 ctcattagtc aaaataactc ctataaagtt taaatctttt ccatgtcttt tatataagtc
    27301 atgtataact ggattattta aatgatggaa tgttgtaacc ttatcacatg gtgctacaca
    27361 gtttccagat attatagctc catccattat ttcagttgga tacataaatg taggcactat
    27421 ctgtttagca tccaccccat agtaataagt gtcatgtaaa agtccttgtg attgtaacat
    27481 gtgaacatat gctactgttg gcaggtctgg atattctttt acttgtttta ataatggctt
    27541 tgtctcatat acaatgactt catctggctc aacttctctt cctgcctcgc ctacatatgc
    27601 acctattttt aatcctgcaa ttctagctgc ttcttcataa tcatgagtat ctataccatc
    27661 ctttgctttt ataacaatac atatattatt tgtttttgaa aaaggtgtat atttagcagt
    27721 aggaccactc atatcaatta cgccttcttg aaatccaact atatttccac aagttacaac
    27781 acaagctcct aaaagtacat gggttcttcc acttcctaca gtcttcactt tatttataat
    27841 tccaggaaat attttgcttt catctccaat tttaactcta ggctctatta catctttaac
    27901 tggagctatt cttattgatt cgccaggtct tgcaagttca acatttacac ttacaatcct
    27961 ttcatcttct aatactatct tttctatttc ttcgctacta atatatagta ctccatcttt
    28021 tacttctgtc ttttctccaa attcaacatt ttttataaat atattcccta gctctagctt
    28081 catatgaaaa tcccccttaa tatatttaat cgcaattaaa agtatttatt acgtttatta
    28141 atatataaag cattttctat gccaattatt taaaatatat attctatgta ttaatgtcat
    28201 agaaattttc atttttaatt tacaccaata ttgaatttac caataattat tgtaaatatt
    28261 aatttttaaa attataataa aaaaagataa acagattttt tctgtttatc ttttaataca
    28321 gtttgagaaa tttttttctc acttaatgag aagttttttt ctcacttaat attatactct
    28381 gatattttat tggttaactg tcttctacta atctccaatt ttttagctgt atttgaaata
    28441 ttatttccac acaaagataa aactttttca atatactcac attcaaactc ttttcttatt
    28501 tctcttaaag gtctaatact tattttatca tctatgtata cattatttga tattaaattt
    28561 aaattgtctt ttgataaatt gccttcttca cttaaaacta caagtctatt tattatattt
    28621 tttaattctc ttatatttcc tggataattg taatttaata aaaaatcctt tacttcctta
    28681 tcaatagagt gtatcttttt atcatgttca atttggtact tatttaagaa aaattctata
    28741 agagtagtta agtcttctct tctctttctt agcggtggta tagttattgt tattgtactt
    28801 attctataaa aaaaatcttc tcttatattt ccatttgata tttccacttt tggttcttta
    28861 ttcatagcac aaattaacct aaagtcaact ttaatagatt tattacttcc tatcctctct
    28921 atagatttgt cctcaagtgt cctcaaaagt tttacctgaa catttagagg tatatctcct
    28981 atttcatcca aaaatagagt tcctttattc gaaagttcaa atctaccttt tctactatct
    29041 actgctcctg taaaagaacc tttttcatga ccaaacagct cagactccaa tagattttct
    29101 gaaaaagaac aacaatttac aggtacaaat atctcattct ttcttggact tatgctatgt
    29161 atatatcttg ctaatatatc ttttcctaca ccagattccc ccaagattaa tatattaaca
    29221 tctttacaag cagctttttt tgctattttt atgatattat taaaatctct atttttagat
    29281 tccaaagtaa attcaaaatt atttttttgt acagaaacag atattttact tgcctttacc
    29341 ttttcaactt cttctaataa attttcaatg ggattacttt ttataaaata agataaagct
    29401 cctcttttca tagcatcaac tgcattttca atacttccat atcctgtaac taatataacc
    29461 tctatatctc tattaataga tttaattcta tctaatagct gtactccatc catatttttc
    29521 atcataacat cagataaaac caaatcataa tttttatctt ttttaattat atttatagct
    29581 tcttcaccac ttagtgctat atctacaaga tagcccttct tttgtagaat ttttttcatt
    29641 accactccat attctagctc atcatcaact aatagtattt tcattatata gtcacctctt
    29701 tatttaatgg aatttttata tgaaaacaag ttccaacccc caatttactt tcaacactta
    29761 tatctccatt attcttttta atctcattat aagtaatata taaacctaaa ccagttccct
    29821 caccaattgg ttttgttgta tagaagggat taaatatgtc ctttagggca tcttctttta
    29881 ttccttcacc attatcttta aaatctataa ataaacaatg atttttttca taacagtata
    29941 taataatttt tccatcttga tgtattgcat ctattgaatt agaaattaaa tttataaata
    30001 catgttttaa cgattctcca tttatatagc atattaaatt atgttcacag tcaattttta
    30061 tttcaacatt ctttaactgt aacattttat attgaagttt cactatattt tcaataaaat
    30121 ttcttatatt tatatgttct aaattatcat ctgatattct tgcgaaattt aacaagttgg
    30181 ttattatatt acttgcccta tctacattac tttctattga tttaacacaa tcatttactt
    30241 cttccattgt aacgttatct tttaagagat agcaattatt tcttattata cccaaaggat
    30301 ttcttatctc atgtgctacc ccagaagcta attgtcctat agatatcatt ttgttttctc
    30361 taagtaattt cgcctctact attttatcat tagttatatc tttaataaga actactatat
    30421 actcagtatt atttttttta tactctacag gaaaagtgtt tatctttaaa attttattgt
    30481 gtatttctat ttcactagtt ttattagtat tttcagagaa ggtattttca ataacacctt
    30541 ttatcatgct aatcaaatct gctatcttat aactcatttc acccataaag tcatatagta
    30601 ctttgttcga ttctactata ttgttatttt catctacaag cattattata tctgtaatac
    30661 tattaaaagt tgcctctaaa gtttttttat tttctattac ctgttctgtt ttccttttga
    30721 tttctatctt taacaaatat gtatagctat aaaaaacata aattgatatt aaaattatac
    30781 ctataaaaag ataaatacta ggcacaattc ctcgctcata caatatatca tcaacttcat
    30841 tatacgtaga ataccatttt ttctttaaat ctttatacac tccatttttc tgaagtttaa
    30901 aaatgccttt atttaaaata ctaaccagct cttcatattg tttaggtaca gcaagaactg
    30961 cttttttagt atatatagga ttacttaaaa cactgtattt atttgaaagt ccataattat
    31021 ttatatagta tcgcaatact ggttcatcac caacaactgc gtctactttt ccagacatta
    31081 aatggttgac tccagtcttt atatctggag tcaataaaat gtttatatct tgaatttttt
    31141 gctttaaaaa atttatagaa taatcacctt ctggaattgc tactgttttc ccctttaaat
    31201 ccatgtaact atttatatct tgggactttt tatctttcaa tatatttgca ctcaaagtgt
    31261 atattgggtc agtaaatata aatttatttg ccctttcttt tgatggaatc aagtcaaaaa
    31321 actttatact atcatctatt gaatttacga aagattcttt ccaccaatta tttggtttaa
    31381 aataaaaatc tctaccaatt tgaattgaca gagaatttat taaatcaaca ataattccct
    31441 tatactgtcc atcttcctta cctttatatc tcaaaggagg tgaactttgg tcagagctgt
    31501 aaatcaaatt cttgtgtttt tctaaccact ttttttcttc ttctgtaaat ggaagtgact
    31561 tcttaatata ttcaaataca tttagattat actccatatt tacatacata tttgtaagtg
    31621 aaaatactac taaaaatgaa taaataatcc ctataataac aatctttttt ttattcactt
    31681 taaaactcca atcttctttt ttactataat aaattcaata tttaataaca aaatcctact
    31741 tttttcatta aatatttata tttattataa aactaattga atagatgttg aaattatagt
    31801 cattactatt cctatcaatg cttcatatgg aattaactta aatctttcac ctatatccat
    31861 gtttatacta cctgcactag tatgaaatag tgagccatgt ggtaattgct cgaatacact
    31921 agacccagca tttactattg atgcacctga aatcggtgat agcccaccat ttattatagc
    31981 atcatgaaaa gtagatgatg ctatagtagc accagctgtt gatgatgctg ttgctaatga
    32041 cataagtata cccgaaactg gtgccaataa aaattgtggc atatttaaaa attgtaaagc
    32101 acctattgta ctctgttgta attcagacat ctgtataatt cctgcgatag tccctgttcc
    32161 aagtaataat atgcataccc cttgcatctt agataatcca aaagctaaat attctcttga
    32221 attgttcaag tttcctgtga caattagagt tacgattcct cctattggaa gggctatcat
    32281 tgggtctata actataggag atacatttcc taaaaacaat agaaatatag ctataattgg
    32341 accacataat gatttaaata aacttggtaa atcttctctt tgctctaaaa tttcatatga
    32401 ttgtacttta tttcctttat ttattaatat acttgctaaa ataactgtaa taacaactcc
    32461 aataattgct ggaattatat ttgccatcat aacactagag agattgacag aaaaattatc
    32521 tgctactgct atagtatttg gatttggtga tattatatta cctgctttac cccctcccaa
    32581 catagctaat agtattgaca atttagaata atttaatttc ctacctatat ataatcctat
    32641 aggtgctaca gttattatag atacatccaa atttacgcct actccagcaa gtaccatagt
    32701 tgaaatggca atcgaaaata aagccctctt ttcaccaaat atttttacaa tctgttctga
    32761 tattttatct actgcccctg tttttattaa acttccagct aatacacctg atgccaaagc
    32821 tctaagaatt gatggtgata tattcatagc tccatttgcc ataaaatcta cagtttgtgt
    32881 tatatttgct cctccaacta atcctccaat aaatgctcct aacattaaac tatatacagc
    32941 ttgaaatttt tttataatta aaataattgc tattaataaa ccaaatatag ctccaaaagt
    33001 cgttatttgc ataatatccc ctcctatcat aaattaacta tcttttgctt aattttattt
    33061 aaatatattt taagtattct gtatccactt tgtcaattat attttaattt atttaattat
    33121 attgaacata gttttttcaa aacctaattc tatatgttat aataatttca tactacataa
    33181 tcattttact tgattatttt aagttaatat tttttaaatt aaaaagagag gatatttata
    33241 tgaatgattt aaatttaggg gaaaaaatag ctgaagttcg aaaaaaacaa aacttaagta
    33301 ttcgagattt agcaaaacta gctgatgtta caccatcatt attgagccaa atagaacgag
    33361 gtcttgctaa tccatctgta aattcattaa aatctatagc ctcttctcta aacgttcctt
    33421 tatttacatt ttttgtatct gaagtagata aaaaaaactt gatagtaaga catgataata
    33481 gaaaaaaagt tattttacct ggaagcaaag aagttatata tgagatttta attccagact
    33541 ctagtggtaa tttagaattt gcaattatgg atttagctcc aaacacttct tcttgtgttg
    33601 ataggattac tcataatgga gatgaaattg catatgtttt ggatggagaa gttaaacttt
    33661 ttatggatga tgatgaattt actttgtcca aaggagatag tgtaaaagtt cctttaggaa
    33721 caaaacataa atggcaaaat gactcaaata gtgaaagtaa agtaattttt gcagtcatct
    33781 tgtaaaggag taaaaaccat gaagatatat aaatttatat tttttgatgc agatgatact
    33841 ttatttgatt ttaagaaaag tgaatcacat gcttttaaaa aacttctatc tgagtttgat
    33901 ttagaattta attttgagaa ttatatagag tcatatagaa atataagtga taagctttgg
    33961 ctcgaccttg aaaaaaatat tataactttg aatgaactta aattacttag atttgaactt
    34021 tttgcaaata aaatatcttt ggatgttgat tctgaaactc ttagcaaaat gtacttaaat
    34081 tttttgggtg aatgtacatt tttaattcca ggtgcaatcg atatattaca atatcttaaa
    34141 aaaaagtata ctattgttat aataacaaat ggaatttctg cagttcaaaa gaaaagactt
    34201 gaaaattcaa aaataaaagg atatattgat ggaatggttg tatctgaaga gttgaaaata
    34261 tcaaaaccaa atcctgaaat atttaaatac gctctcaaaa agtttaattg tcatgataaa
    34321 tcttctgcct taatgattgg ggatagctta acctctgata tcttaggtgg aataaattca
    34381 ggaatagata cttgttggtt aaattccaat aacagtataa attatactaa tcatatacca
    34441 gcttatgaaa taaatacact tattgaatta aagaaactac tatagtttgt aagtctgttc
    34501 aaattaaata gaatattact ttgcaataat ttttttagtt tatacataaa atgaccaaaa
    34561 aaattattgc aatttataca caaaacaaat cttagtcttg aaaactaact aaaagcattt
    34621 tctaggacac ttactacatc ttgattctaa attttcttca tcccccatta aaataagcat
    34681 tgcaacactt tttatggggg atagttgatg ataatcattg atttctattt ctatactatt
    34741 atatttattt tttacatagt tataaatatc cttttgtctc tctacttcaa aatctttatc
    34801 tcctggatat atttcatgcg atattttgag actatcatac tttcctttta aatacatttt
    34861 tattttctca ttaatataat ctaaacatac tatacctatt ttatccaatg ctagccctgc
    34921 catcatattg caattttcca tatagtcatt catcttaaaa tcaattttat cccctattgt
    34981 atatagtaca gcaaatgctt ttttacattc tttaggtgtt ttattaatat caacttcact
    35041 tatatatatc ttgatatcta aaatatcatt tatatttctt atttctcttt caacgatttt
    35101 actaattgta tctggagctt ttctatttcc ataccccaaa aactttagca caatattctt
    35161 atctataaaa atatcatcta aatttatatc ctttaaaaga tatttatttt tattactatt
    35221 ataattcatc aatatcaatc ctatctaatt ctttataact aattcttcct gcctttatag
    35281 ctgcttgtaa attttctact ggagtggtat ttaagcagtt acagccaaaa tcacataaaa
    35341 agttatcata tcctctcatc ttctttaaca attttagtgt ctctcttcta atcttatctg
    35401 gcttagaacg tccaagaagt tttattgggt ctaaattacc aatcaacact atatctctag
    35461 gaatcattgg agcaatttct tcatagtcta aaatttggtc taaacttact gcatctatat
    35521 tacaacttag catattatct aataattctc tggtgtctcc acatatatgc atacctttcc
    35581 aacaatcaag ttcattgtag attttattta aattttttac tataaattca tcaaatctat
    35641 ctttacttag ggttactgat gttggctctg ctattgaaat atattttgct cctgctttat
    35701 ttgcagctac agcatatctt cttaccaatt cagttgtaaa ttccaataat tcttctacaa
    35761 attttttatc agttattata catcttaaaa gttgagtagc tccagctaat tgacctgcaa
    35821 gtgtaaatgg accttgtatc gattcatata gtggtttttt aatacttttt gatataactg
    35881 ataagctctc tatattgagt ggcatacgtc cactcgtata agggtctgga acatctaatt
    35941 ttcttaattt atctctgtca gttatagtat gtgtcaatac acttggaaaa tcataatctg
    36001 gtcttaatgt ctctaaaccc agagtttcac aaaatgtaat cccatcacag aatgagtata
    36061 taaaatctga ttcaaaatac ttgtccatag tctttgctaa ttctaattgc aaatctacac
    36121 tatcatatac ttcatatgcc tttttattta ttaagaacaa tccatttgta cccatatcag
    36181 gcagaaaaaa acctctatct tcactattta tatactgaag taaagtcata tctgaaaaca
    36241 tttaaacttc acctcctata agtttattta ttaatttaac tgcttttgga gcatttgaac
    36301 tgtatccatc tgctcctatt tcttctgcaa actccatact tacaggacct ccaccaatta
    36361 ttacttttgg tcttttatct atctcaatca tattaagttc gtctataact gatttcatat
    36421 tttccatcgt agttgtcatc attgaagata agcctattat atctacattg ttttttatag
    36481 cttcttctat tatatcttca ctttttctat ttacacctaa gtcaataacc ttatatccag
    36541 tggcttctac cattactttt acaatatttt ttcctatctc atgagtatct ccttctacta
    36601 cagacatcag aattactccc tttgattttt tctttacttt tccagttccc ttcaaaagat
    36661 taataccttt atttaatgca tctgtgcata ctataacttc tgaaagatag tattccttat
    36721 tctcaaactt atctaaagct cctatcatac ctttgtttaa accatattca taaatatctt
    36781 ccacatcaat atttttatct atagcaattt ttactaaatt ctctatatta tctacaccca
    36841 tatttaatat acattctgct atatcatcaa gtatgtccat ataatactca tcctttctaa
    36901 ttacttacaa aattgctttt tcaatatcca ataatttctc ttatttaaca aggactaact
    36961 ctaggtatca atcaatttta tttaatatca tctaaaacta ttgataattt aaatttgcag
    37021 tccatggaaa atctacagga aatgcctttg tagcaaattc atatatattt tttagatgtt
    37081 taaattcatt gtactgttcc tcattttttt caaaaaacag tttattaagc ttatccaaat
    37141 tttctattac aagttcttct tctttgtatt taataatata tttattttca acttgtttaa
    37201 attccatgta ttttagtaat tcaaaatcta catattgact aaaataactt cttaaactat
    37261 cacacaactt agtaaaattt attattttca tagttccttg ttgatagtcc aaagattttg
    37321 tcccattaca tttcaactgg tctttaagat ttttcacatg tactttataa tttaaatatt
    37381 ctaatccaaa tttatttgca acatatttca atatattttc aacatttaca gagtttaacc
    37441 ctatttcagc aacttctcct acagtagaat cttctttttt tattgttctt attatcaaat
    37501 atcctattat attattattt tcctttataa ataccttctt gtaaccaatt ggtccccagg
    37561 caatagttgc tgcatgcaat agtttttgaa actcatctct cgttcttata aatctagtac
    37621 tattttgatt atatagttca atcattttat ctaaatcatt atctttttca aaattagttt
    37681 catcaaattc aactatttca tatgctattt ttacatcttc aggttttatt gtatatttat
    37741 aaaaactctt taccaaacta caatttcttc tactgtatag acttcttgtt cctgatataa
    37801 ttacaatatc tacaccatca taaaacattt tttcttctac tttatccaat atcttagatg
    37861 aatagcctct cttttcataa tctggatgag tacatactcc acctatagct gcaaccttca
    37921 atctgtttcc ttgaatagat acatcttgaa ttagatagtt tacatcagaa accactttat
    37981 catcttttga tattataatc atattttcta tattattttt acttagtaaa agaggaaatt
    38041 cttccatcat agttggttta tgacttcttg atattctaaa tacatagttt attaattcta
    38101 ttactttatc aaattcttct aattttgcac ttcttggtct taattccatt catattcctc
    38161 caaatattat ttaagatact taaaactcta ttatctataa taaaacattt attactacag
    38221 ttctaattat atcttttttc tttacaattt ttaattgttt tttttagcaa atttttataa
    38281 aatataaacc taatttatag ttaaacttat aaaataaccc gttatgtata atatattaaa
    38341 atattttcta tatatttata tgactaagtt ctataactaa attgaaataa tcactttttc
    38401 aagaatgtta taattttttt attgtattct ttttgctata gtctatgaat aaatcaatag
    38461 aaaatcttct aagttgcttt taaataatga ctttatggtt caattgtact aaaatagtat
    38521 atgtaggtta caaataatct aataaatatt aaagtttgga ggtaatagat atggcagatt
    38581 gtaattcatg tccatcaaag ggaaattgta atagtcaatc aaattgttct attgaaaata
    38641 accctaacaa taaatttgga aaaataattg gtgttatgag tgggaagggt ggagttggaa
    38701 aatcaactgt aactgcttta cttgctaata agctaaacaa aatgggatat aaggttggta
    38761 tattagactc agatataact ggaccaagta ttcctagact tatgggtgta aaaaatgtaa
    38821 aagcttattc tgatggctct tatatttacc ctgtagaaaa ctcaaataac ataaaagtaa
    38881 tgtctataaa ccttatgata gatgatgaaa atgaacctgt tgtttggaga ggacctttac
    38941 ttggaggggt tgtaaagcaa ttttatactg atgtactttg ggaagaatta gactatttat
    39001 taatagatat gcctcctggt actggagatg ttgccttaac agttatgcaa tctattccta
    39061 taagtggaat agttatggtt tcagtacctc aagatttggt atctatgatt gtatcaaaag
    39121 ctgttaatat ggctaaaaaa atgaacataa atgtccttgg agttattgaa aatatgagtt
    39181 atatccaatg tcctgattgt tctaaaaaaa tcaagttatt tgaaggagaa tctactgaaa
    39241 agtttttaga tgatttagac ttagagcttt taggagaact tcctatgact aaagaaatta
    39301 tagatattac tcataatgga gttacagaaa ttagtgatga tttagattca atattgacta
    39361 atgttgttga aaaaattaaa taaataaaaa ttttataatt ttatatttat caaaaaaaga
    39421 ggcttgtatt tattttataa tcatacaaat aaatataaac ctcttttatg tttatctatg
    39481 ttttaaatac acaaaatatt cttctacttc atctccattt tttactttta ctaagtattc
    39541 attataatga gcattatatg gctgtgtcat tttgcattct attacatttt ctatgtcttc
    39601 taattctaaa agttctacat cctttaaaaa ttttctttct atgagttcca ttaatctttc
    39661 cataatatat cctcacttcc cctataatta agataaacta tatatcctct taatacagag
    39721 tttatctgtt tattatatta tatccaatat attacagttt ctaacatcat tcataaatta
    39781 ttttaacaaa tagagattga ttttttaata gatatgcctt gataaaatga aacatagacc
    39841 aactcttagt tttatgtaaa gaaaacttaa agaaaactat agattatatt cacaaaaatt
    39901 actcagaaga tataacagta agtaatatat gtaatgaatt acaacttaat aaaagttgtt
    39961 tttttctttg tttaagaaaa aaagtggata tacttttact aattttttaa gtaaagttag
    40021 agttgaaaaa agcaaaaagt atatattaaa aaaaaacttg tctattttag acgttgctgt
    40081 actaattgga ttcaatagtc aaaattacta tagtataatt tttaaaaagt ttaataactt
    40141 tacaccaatt gaatataaaa atatttataa ctaaaaaata tcattctaaa aggatgttat
    40201 ttttttacaa ttatagttaa ttctttgtta aattgattgt acataaaata ctaaaaatct
    40261 aagttcaagt atttaaattg ctatatatca taaattttct aaaattaaca acaacttaaa
    40321 aatttaacat tctcttaacg tatacttaac aaaacattaa tatttttatt gacaaaattt
    40381 gttattctat attatggaaa caataaattt tagttaataa agtttataat tcagataaaa
    40441 aaattattaa tttcttaagg gaggaaatat cgtgaatata gtaattagcc ttatcggtgg
    40501 acttggactt tttctttacg gaatgagttt aatgggagaa ggtttacaaa aatcagcagg
    40561 agacaaatta aaaaaaatta ttgaactctt aacaagtaat gttgttatgg gtgtactggt
    40621 gggtacagtc gttacaggta ttatacaaag ttcaagtgct actactgtta tggttgtagg
    40681 atttgtaaat gcaggtataa tgaatctaag tcaagctatt ggtgtaataa tgggggcaaa
    40741 tataggtact acagttactg ctcaattagt ttcatttaat cttgaaggaa ttgcaccaat
    40801 tgctttaggt ataggtattt tattctattt atttacatca aatcaaaaaa caaagcattt
    40861 atctgagata cttataggtt ttggtatatt atttacagga atggagttta tgaaagatgc
    40921 agtagctcca cttgctgaat ataaagcatt cactgatgca cttttatatt ttagtaaaaa
    40981 tcctgtatta ggtatattgg caggatttgc cataactggt attgttcaaa gttcaagtgc
    41041 atctatgggt atgttaatag cactagcttc tcaaggaata cttcctctat catctgcttt
    41101 acctattctt tatggagata atataggtac ttgtgttact tcacttttat caagtgttgg
    41161 tgcaagtaga aatgctcgac gtgcagctgt aatgcattta agttttaatg taattggtac
    41221 aataatattt atgcttgttt taaataaacc tatatcagcc atagttactc attttgaccc
    41281 aactgataca gctagacaaa tagcaaatgc acatacttta tttaatctta caaatgttat
    41341 aatattatta ccattttcta aatacatagt taaattagca aatagactta tacctattaa
    41401 agaaactgaa tcagaaatag taaataatac taagtactta gatgaaagga tgtttagcac
    41461 tccatctata gcacttggta atactgtaca agaagttgta agaatgggtc ataaagctac
    41521 aaactctttg gaacattcaa ttgcaggatt tttaaataag agcaatgaag atattaataa
    41581 atcttttgag tcagaaaaag ttgtcaataa gttacagaaa gatatattga actatttgtt
    41641 aaaactttct aaagaacctc ttagagatga tgaacgcttt agaacagatt tgctttttaa
    41701 tactgtaaat gacattgaaa gagtctctga ccatgcagaa aatatagctg aattggccat
    41761 gagtgttaag gaaatgaaca ttagtttttc tgatagtgcg ataagagaaa tatacgaaat
    41821 atacaataag acaattacta attttaagga tgccttaata gttttagatg ttaaagattt
    41881 tgagttggca aataaagttt tagaagttga aaatgaagta aattatttag aaaaaacttt
    41941 tagaaattca catatgatta gactaaataa tggaagttgt acaattgatg ctggtgtact
    42001 ttatcttgac ttacttacta atctagaaag aatttctgac cactcaacaa atatagtaaa
    42061 acaagtacta aaacttaaac aaaaaatata gtgattattt ttatatataa tcttaatcaa
    42121 tgagaagtaa gaagctatag ataatgctta tatcatttat ggcttcttat tttttatgta
    42181 atactcaaat ttttatagta ttctcttatt attaaacaat ttctgcctag aatattccat
    42241 atatatatga cttctttcat aaaacttgaa ctgcccataa ctaaagtcac aagtatacat
    42301 aactattttt taatcaatta taaccaatat ttgttttatt tatcttcatt ttaattcttc
    42361 attcaataat gtaataagat tattttttat ttggatacta ttatatcatc taaatatgtt
    42421 attatatatt tggatatttt catattaata ggagggattc tacaatgata aattatatgg
    42481 tagaaattat atatagcgaa aaaataagcg aagtagaaaa catgttgaaa attgaaaata
    42541 tacaatatga atttacttct cgtgatggct ttatattttt tggtttttat gatatgacag
    42601 acgcatatag atttgagact ttatgttcag atgaaaaaat tcgatttaaa agaatataat
    42661 agataaaaaa gtacatattt ctaaactatt tgtttttcaa atttaggttg tgttttaatg
    42721 tagtgttgat attataaaca attttaataa taaaaaagta gggacattat attaatatgc
    42781 tcctactttt tactcatact tattaatatt atttatcaaa attaccctac aaactggaat
    42841 ttatcattct ttcataattt taaactatca tatttaaaat atataaaatt ctacatgatt
    42901 tttgtataaa cataatatca atcattatcc aatttaaaaa tattttttag taatttccat
    42961 ttcattttct cttaacatat taattaaact tttatatgta aatggtgtat ttacatatta
    43021 tttaatatcc aacaattata taaagaaatg tgctctttgc cttataaaga attataaagc
    43081 caattcgttt tattatatta tttgtcttta taccttaaaa actttacctt caaattctta
    43141 tttatctata tattataaaa atgttcttaa cctcttttac gagattttct tgacatatta
    43201 tcagttagat aaaataatta aataatataa tcagcaagta tgttttttac tcttttaagt
    43261 aagtttccac ctgcacccca atcaattttt aaaattccaa ttgcactgcc tgttgaagta
    43321 gctttaataa ctgtttttcc tgtggtattt tcataaacta ctattaatcc tgcatcacta
    43381 ttatttcttg cgtaatactt ctcaaaagtt gtaattagta taaatttatc atctcctaaa
    43441 ttataagaat cactaaaaac taaatctgca tcaagatttt cttttatcat tttttgtgcc
    43501 tctaagggtg taatttttac agtaaatatt tctgttgcca ttttttatct cctcataaga
    43561 atttatttta gacaaaacat aatctctagt attttctgat atatttatca aacaatatcc
    43621 ctattcctcc taacagagct aatatagaac caaaatttct atattgagaa atagattggt
    43681 ctagataaat attatattgg tcagtatcca tgattccacc attttgttga ataatatgct
    43741 ctgcactaaa ttcacctaaa cctatacagc agaataatac tactactcca attacaaaag
    43801 caaatataca tactgttaat ttaaaatcct tattttccat agttatccct ctcataagct
    43861 aaatttattt gattattttt actagatttt atattactct tattatacaa tacaacatat
    43921 atttacatct atttccaaaa ttgtaacctt tatagtttta tatatttaaa ttttttaaac
    43981 aaaaaataca catctataaa ttataaatgt gtattctgta ccattactaa taatatatta
    44041 tactttttta caaatttcta attatttata actattcaaa aataaaattc atataaaata
    44101 attctattgt acaattgaaa ctttaataat gtctccattt tttctctcca agtggactac
    44161 ttctccagtt aaatcatagt caaatgcctt aactaatatt tcagtaactt ttttaccatc
    44221 tactacatca tcttttccat taaataaatc caaagcatta ttctcaatca ttctctttgc
    44281 aaaatttaca ggtaacttta tatgtatttt atcgcctgta tgtgataaga ctcttattct
    44341 taaaaacttt tctaaattgt ttcttggtat ttgttttgat gccatgctat taaatcactc
    44401 tcctttattt tttatttaat aataaatttt attcttaaaa atatctttat atgtatttat
    44461 tatgaaagta acactattat t
//
LOCUS       DAEQAF010000021        43866 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.022, whole genome shotgun sequence.
ACCESSION   DAEQAF010000021 DAEQAF010000000
VERSION     DAEQAF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43866
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.022"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            86..1144
                     /locus_tag="KRN00_001287"
     CDS             86..1144
                     /locus_tag="KRN00_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBH1827154.1"
                     /translation="MIVCNNPGTWMRMYPQLRHAVWHGVTLADFAFPFFVISLGVTIP
                     ISINSKLKNNKSTLSIILSIFKRSILLILFGFFLNYLGNPDLDTVRILGVLQRMGLVY
                     FVTSLVYLLLKKLNVGSTATIITFLCISTFIIVGYYILAKPYGFELEGSLAQLVDLHF
                     FKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKENLGEYKKFFKILVMSIILLI
                     GAFIFNQYFPFNKRLWSSSFVLLMAGSYGILLSIFYFICDIKNKSKIFTPIIALGSSP
                     IFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELITPWAGTTWDSLIFSLLYVL
                     FWVIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="KRN00_001288"
     CDS             1398..3422
                     /locus_tag="KRN00_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1827155.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQNIKINGKDEQKILNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKIIDQISKIAKNGTSKNRVSGADRHETNANVIKT
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHSTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGAGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="KRN00_001289"
     CDS             3642..4328
                     /locus_tag="KRN00_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBH1827156.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="KRN00_001290"
     CDS             4423..5478
                     /locus_tag="KRN00_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBH1827157.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAVSKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFKSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="KRN00_001291"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="KRN00_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH1827158.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGDGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="KRN00_001292"
     CDS             7195..8901
                     /locus_tag="KRN00_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBH1827159.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSTIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDEYGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="KRN00_001293"
     CDS             8923..9996
                     /locus_tag="KRN00_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBH1827160.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="KRN00_001294"
     CDS             10008..10730
                     /locus_tag="KRN00_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1827161.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="KRN00_001295"
     CDS             10746..11903
                     /locus_tag="KRN00_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBH1827162.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="KRN00_001296"
     CDS             11906..12745
                     /locus_tag="KRN00_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1827163.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="KRN00_001297"
     CDS             12760..13935
                     /locus_tag="KRN00_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBH1827164.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="KRN00_001298"
     CDS             13964..14713
                     /locus_tag="KRN00_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1827165.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="KRN00_001299"
     CDS             14735..15643
                     /locus_tag="KRN00_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1827166.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="KRN00_001300"
     CDS             15691..16443
                     /locus_tag="KRN00_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1827167.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16397..17764
                     /locus_tag="KRN00_001301"
     CDS             16397..17764
                     /locus_tag="KRN00_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBH1827168.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17770..18861
                     /locus_tag="KRN00_001302"
     CDS             17770..18861
                     /locus_tag="KRN00_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1827169.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="KRN00_001303"
     CDS             18945..20858
                     /locus_tag="KRN00_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1827170.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISVCIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFVATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDVCKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="KRN00_001304"
     CDS             21057..21764
                     /locus_tag="KRN00_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBH1827171.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            22066..24177
                     /locus_tag="KRN00_001305"
     CDS             22066..24177
                     /locus_tag="KRN00_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBH1827172.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDDWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNLVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDTVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24375..25340)
                     /locus_tag="KRN00_001306"
     CDS             complement(24375..25340)
                     /locus_tag="KRN00_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH1827173.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLN
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25625..26581)
                     /locus_tag="KRN00_001307"
     CDS             complement(25625..26581)
                     /locus_tag="KRN00_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBH1827174.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26949..27737
                     /locus_tag="KRN00_001308"
     CDS             26949..27737
                     /locus_tag="KRN00_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1827175.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKEEAFIQEVSTYYAKFKTVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27860..28330)
                     /locus_tag="KRN00_001309"
     CDS             complement(27860..28330)
                     /locus_tag="KRN00_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBH1827176.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28469..29113
                     /gene="uppS"
                     /locus_tag="KRN00_001310"
     CDS             28469..29113
                     /gene="uppS"
                     /locus_tag="KRN00_001310"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBH1827177.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29156..30061
                     /locus_tag="KRN00_001311"
     CDS             29156..30061
                     /locus_tag="KRN00_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1827178.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30376..31923
                     /locus_tag="KRN00_001312"
     CDS             30376..31923
                     /locus_tag="KRN00_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1827179.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINNIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31926..32324
                     /locus_tag="KRN00_001313"
     CDS             31926..32324
                     /locus_tag="KRN00_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH1827180.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32364..34097
                     /locus_tag="KRN00_001314"
     CDS             32364..34097
                     /locus_tag="KRN00_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBH1827181.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYILDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34329..35540
                     /locus_tag="KRN00_001315"
     CDS             34329..35540
                     /locus_tag="KRN00_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1827182.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35734..35994
                     /locus_tag="KRN00_001316"
     CDS             35734..35994
                     /locus_tag="KRN00_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBH1827183.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36348..38060
                     /gene="ptsP"
                     /locus_tag="KRN00_001317"
     CDS             36348..38060
                     /gene="ptsP"
                     /locus_tag="KRN00_001317"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBH1827184.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKNYIEK
                     TFNI"
     gene            38383..39933
                     /locus_tag="KRN00_001318"
     CDS             38383..39933
                     /locus_tag="KRN00_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1827185.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     ENLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            39959..42661
                     /locus_tag="KRN00_001319"
     CDS             39959..42661
                     /locus_tag="KRN00_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1827186.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNVYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIS
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVEVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDVKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSVQQIVHKQCANDILSCIENCGLDKKYICVEVTETVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQIAKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
     gene            complement(43167..43832)
                     /locus_tag="KRN00_001320"
     CDS             complement(43167..43832)
                     /locus_tag="KRN00_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827187.1"
                     /translation="MKGNIVQYNFADIEEEVYSLDYAIAWNTDEENVNIIPFTNKFCK
                     ESIESFCLGKINNFVEILNEGFVENHHYVHLDKMISVPKKKVNLVYQQDTHGYLLRDD
                     NDNLIPAKITSEQSKSISSKMELFCAGEEKCLINILLKADPSYILDVDSIKDKNILNL
                     GYESIDRYKEYNFDDDKILIFFINKKRYSVIMKKTNNSDNDLVSRNNAIKELFTNKAG
                     NLN"
BASE COUNT        17448 a         4539 c         7669 g        14210 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tacgaataat aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaaactaaa
      241 aaataataaa tccacactga gtataatact tagtatattc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attacctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agtttagtat atttactact
      421 aaaaaaatta aatgttggaa gcactgctac aataattact tttctatgta tatctacatt
      481 tataatagtt gggtactaca tcttagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa gggacatttg tacaagccgg aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaaa acctaggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 gttatggtct agctcatttg tacttttaat ggctggcagt tatggtatat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tggaagtagc cctattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttatatttt ctttattgta
     1081 tgtcctattc tgggttatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagat gataaagtct ttgatttgtt caaatatacg gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagattta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgttgtctg
     1441 tagcaatggt ggcaccaaat gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aataacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaaacataa
     1741 aaataaatgg taaagatgaa cagaaaattt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacagggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaaattata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag actttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aaaacttatg
     2701 tttctgcata ccatagtaca aacttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggagctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataat aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaatagaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagagtt gatagaaggg agtataccag agatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc agtatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaagaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agagtttatt gcagagattg attctaactt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag tagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaagagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaagata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaatgt atggatactg ccagcaggag cattattggc tatggcgagt
     6181 cagttattgt ttcaactgcc atttgcgttt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtctat aaaagagtta gtcaacctag tattgcctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gaccgattat tggcaaccac tttgggtgat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagcac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttagaatatt attccaaagg
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atcaaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagattcta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaagc aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ctattaaaag tatagatttt gaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaagca agttttaaga
     7861 caaaatataa tagatgaata cgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gctttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga acaatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaagct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagcaatga tagaagtttt
     8401 ataatgggat atgaggaaag ctatggttac ttaattggaa ctcatgctag agataaagat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatggtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa caatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaacg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tacgatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcaacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctaatct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtatt atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgacccaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcagca tgttttttaa
    11101 tggtagctat attattattt aatctatttc cttcattgat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaataattt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccga
    11461 taatacttac tttatttagt gtaattattg gtacagtatt tgataaaagc actttattaa
    11521 atagattatt agcaagtaga cctaagttct ggcatgtata cttggctgaa aaggggaatt
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggacag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagact atacaagatt tgatgaaaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaagaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cagatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agccgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagtaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgtagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagag tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaagtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggctca gccaacctag attatataaa ggcagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagagcttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagatact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatacgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgactct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatttcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggaagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aagcataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagtgtgt atatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttgtgg caactttagc ttatttaatt ccgatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggcgcaagaa tagcctatag agctataaga atagtcatga
    19381 acaagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taagaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca taatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agtacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag agattattga tgtatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaagc
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcctaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgcaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt aaaaacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gttatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtacttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttata tgaagaacta cttatgtcag
    20641 aagaaggtct gttggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtgccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tataaatggg gagcaactgg accaaattct tttgattgtt
    21481 ctgggttcac ttcttatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaaa aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg ttttttttat aataaattat ttcatattat aatcaaatat caaatataaa
    21961 ttttaactat attattcaat atttgacaga taatatgaat tttagatata cttaataaga
    22021 agtatattgt agaaaaaata aatttaaaaa attaaggggg atgaaatgaa aaaaataagt
    22081 atattagtat tatcattgat aatgacactt actatgtgta gtgtaagttc atttgctgat
    22141 tcatcaaatg ataaggaaat gagagctgct tggatatcta cagtttataa tttagactgg
    22201 cctaagacta agaataatga agccaagcaa aaaaaggaat acacagattt attggacaaa
    22261 ttaaaaagtg taggaataaa tacagcagtg gttcaagtaa gaccaaaatc agatgcttta
    22321 tataaatcaa atataaaccc atggtctgaa tatcttaccg gtacacaagg taaagaccct
    22381 ggatatgacc cattaccatt tttaatagaa gaagcacata aaagaggaat ggaatttcat
    22441 gcatggttta atccatatag aataactatg gcagatgaga gcatagataa attgccagca
    22501 aatcatccag caaagaaaaa tccaagctgg gtagttaaac atggaaataa gtattactac
    22561 gacccaggtt taccagaagt tagaaagtac atagtggata gtatagcaga agtagttcaa
    22621 aattacgata tagatggagt tcattttgat gattacttct atccaggagt aagtttcaat
    22681 gatactgcaa cataccaaaa atatggaaaa ggacaaaata aggatgattg gagaagagaa
    22741 aatgtaaata ctctacttag agatgtaaaa gcgtctataa agagtataaa gcctaatgtt
    22801 gtatttggtg taagcccagc aggtatatgg agaaataaga gtagtgaccc aacaggttca
    22861 gatacatcag gtaatgaaag ttatgtaggt acatatgcag atacaagagc atggataaaa
    22921 caaggattga ttgactatgt agttccacaa ctttactggc caattggtct taaagcagca
    22981 gattattcta aattagtggc atggtgggct aatgaagtaa aaggaacaaa tgtagactta
    23041 tacataggac aaggtatata taagcaaggt caatcgagtt atggtggaca aaatatagca
    23101 aaagaaatag tacaacaagt aacattaaat agaaagtata gtgaaataaa aggtagtatg
    23161 tatttctcag ctaaagatat agcaaatagt acttctatac aaaaggattt aaagagttta
    23221 tattctagta gtgaagaacc agttactcca ccatctaatg ttaaagtgga gaaattaaga
    23281 ggcgacgaaa gatatgacac agcagtagca ataagtaaaa aaggttgggc tacaaattca
    23341 gatacagtag tattagtaaa tgggtactct atagttgatg gtataacatc aacaccactt
    23401 gctacatcaa atgatgctcc tatactattg gtaaataagg ataatatacc tacatccact
    23461 aagaatgagt taaaaagact taatccaagt aaagttattt taattggagg aaataactct
    23521 attggagata aagttgagag tgagataaaa gatacattgt caaatgtatc aataaataga
    23581 gttggtggtt cagatagata tagtacatct ttaatgatag caaaagaatt agtaaaaact
    23641 aatctagtag aaaaactata tataacaagt ggtacaggtg aagcagattc tctttctata
    23701 gcttcaaaag caggagaaga aaagcaacca atagtattag tatcaaaaga tactgtaagt
    23761 gatgaagttt acaattggat atcagattta aaagtaaaag atgcttattt tataggtggt
    23821 aatctaagta tatctgattc agtaataaat aagctggata aggtcattac aaatgatgta
    23881 tctaaaaata gaatagctgg agaaaataga gaagaaacaa atggaaaagt aatacaaaaa
    23941 ttctatccaa atgctgaata ttcatcaatg tttgtaagta aaagtaatca attggtggat
    24001 gcattaacat caggtccttt agcagctaaa ttaaaatcac cagtagttat gcttggaaat
    24061 agtgtaacat ctgctcagaa aactgcttta gagcctaaga aaactactct agtatacgaa
    24121 gctggagatg gtataaatca aaacacatta aacactttct taaacttagt taagtaataa
    24181 aaaagttaat ttaaaataca gagtatttta taaatgtaga ttaaaatgaa aattatcatg
    24241 ataaattaga aaataaaaaa gaactatatg cattttgtaa tcaagtgtac acagcaactt
    24301 gaaaataatt atgcgatata gttctttttt agtaattaat cttatacttt ttaataaact
    24361 ttatgttgaa ttttttattg tttaaactct atgtcattaa atataaaatc gtgtaatatg
    24421 tctaaagtat ctgggtcaaa tctaagaacc catccagctt ttccatatat accacctgta
    24481 ctatgaattt catcatcaat aggaaattca aattgcttaa tatttaagtc gcccattttt
    24541 aaaacttgag ctcctaaaga aagtattgca ttaggcttca tgttagtttt aacatatgga
    24601 agaactgcat ctaataaacc tggatattta gtaacaggta aagtttccgt tttcttgatt
    24661 atagcttgta taatctgtct ctgtctgcca tctctagcaa aggctgtatc gttgtgtctg
    24721 atacgtgcaa aagatagtgc ctgatatcca tttagagtct gctttccaga gtttctaatg
    24781 tattgtatgc tacctttatc atcactttta ttccatttat aagtttcagg aataaattta
    24841 tttagttctc gtatttctcc tttttcaaca gtaacctcaa cgccaccaat agcatcaatt
    24901 atatacataa atgattcgaa attaacacaa gcataatttt gaatatcaat attaaaattc
    24961 tcttcaattg tttgtattaa taaatcagct tgtccataag cataagcatg agtaagtttt
    25021 tgtttaccat gaccagggat gtctacatag ctatcacgag ctaatgatgt aagtttgata
    25081 tcattgtgtt tgttatcaat agtaagtatc atcatagcat ctgaccttga agaatcttca
    25141 tttggtctag catctgttcc cataagtagt atgttaatta tcccatcttc atttttatgg
    25201 tcattgttat tcaataaatc actacttatg ctcgagtcat gaatagcaga taatttataa
    25261 taaaaatatc catagacact tatagggaat attactacca agaaagccag tagtataaca
    25321 aatttcttta attttgacaa aagtacccct tctttcttct ttttcctgta tattttttaa
    25381 tagcatacac ttaattatat taaagtattg agatatattc aatacttgtt tcagttacaa
    25441 aaaaaagaca atgatataat ttataagaaa atttatcgac ctatatatat agttaaaagt
    25501 atatataata tattttttaa aagtaattta tattttaaaa taaaaacaca ccccataaat
    25561 acaaagtaat ttgcatttaa gaggtatgta tttatcatca aattattggt ttgttttgga
    25621 atttctaatc ttcaaccata atatctttaa atatgaaatc atgcattgca tctagttcat
    25681 attcctcaaa aggtattaca tagcctgcat tacctatttt tctaccattt tcagtagaaa
    25741 gaggaaactc catagatttc aaatttaaat ttcctatact taaaagttct tttcctaaag
    25801 atattatttc attaggattc atattagttt ttacatacgg aagtattgtg ttaactagat
    25861 taggatattt agtgactggt aaatccttaa caccatttat taaactctgt ataacacttc
    25921 tttgtcttct atctctttca tctgtactat cattttttct tatacgagaa aatgcaagtg
    25981 tctgatatcc atttaatttt tgctcaccag aatttcttat atatttaaga gaacctttat
    26041 tgtcattttt attccattta taagtttcag gaataaattt atttaattct cttatttcac
    26101 tcttatcaac agtaacagta actccaccta aagcatcaac tatatccata aaagagaaaa
    26161 agtcaactac ggcgtagttt tgtatatcaa gttggaagtt ttcttctata gtttctatta
    26221 ataagttagc ttgtccatat acgtaggcat gtgttaattt ttgttctcca cgtcctggta
    26281 tattaacata agtatctcta tttaatgaag ttagcttaag acttttattt ttattatcaa
    26341 tagtaagtat catcatggca tcagaacgag aaacttcttc tcctggtctt gcatctgtac
    26401 ctaacaataa tatgtttgtg atattttctt cgtttttata gtcattacta ctaagcgcct
    26461 ctgtatttat actatcatct tgtatagttt ttaatttagt aaaaacatat ccatatatac
    26521 taacaggaaa tgctataact aaaagggcta gaaatataac gaactttttg agtcctgaca
    26581 ataatatccc ctactttcta aattttttaa ttacacatag ttaattatat taaaaatttg
    26641 ttacataagc aataaaaaac acaataaatt agcataagtt tgtcataata taattatttt
    26701 tatagtattt tatagaagaa agtgtgtagt tattattgat tttattggaa tataattgta
    26761 tgaagactta aatttttata aactgatgtg tatattgaaa aaaatatttt cctgaatgta
    26821 gttatagcat cttatgaaag gtgcaaattg taatttaaaa tttttagtgt ataataagaa
    26881 ttgaaaattc aaaccgataa aaattaataa aaaataatta taaattaata atttggggga
    26941 ggaaatgtat gataaaatta atagcaacag atttagatgg aactttgtta gatgaaaaga
    27001 gcgaaataaa tccagagttt tataaagtat ttaaaaaatt aagagagaga gggataatgt
    27061 tttctgctgc tagtggcagg cagtatcaaa atcttataaa aaaatttgaa gatataaaag
    27121 atgatatgat gtttatatca gaaaatggaa cactagtagt atataaagga aaagaaatat
    27181 tatcaaatcc tttaaataaa gaattagtaa atgaaatcat agagacaaca agaagtataa
    27241 aagggaaaaa aattgtaatg agtgggaaaa aatacgctta tatagaaagc aaagaagaag
    27301 cgtttataca agaggtcagt acttattatg caaagtttaa aactgtagaa gatttgacga
    27361 aagtagaggg agacatattg aagatagctg tgtttgactt caaaggtgca gaacataata
    27421 ataatatcta ctttgaaaag ttttctgata gagctcaagt atgtatttct ggagtggagt
    27481 ggcttgattt aactgcaaaa ggtgcaaata aagggagtgc cataaaaaaa gtacaaaaaa
    27541 tgttagatat aaaatatgaa gaaactatgg tatttggtga ccagttaaat gatgtggaaa
    27601 tgatgaaaag tgcctatcat agttatgcca tggaaaatgc aaatgaacat ttgaaacaaa
    27661 ttgctagatt tagagcaaaa agaaatactg aaaatggcgt tgtagataag ataaaagagg
    27721 ttataaaaat tggatagtca tatgtataga tgaaaaagat tattttgaag aaatcaaaaa
    27781 aatatcaatg taattttgat aaataagttt atttatgcga aaattacatt gatatttaat
    27841 aaacatcaat aatagatatt tattttttta tgatattcag tattttgttt tctatttgag
    27901 ttgcattttc agcagaaatt aaataaacat atctacctgc cttctcaatt atagtattat
    27961 ttgctatttc agaattgatt ttttctccat gtccttctcc aaaaggtgct tgtatcatat
    28021 cttttttata attttctaga gttttataga ttttatctac ctcgtcagtt tttataacga
    28081 taatatcttc tagagataat ttttcagaag aattaattac aaaaccttga attatgtctt
    28141 cctctacatc attaaaatag ttaaaatcct ttgcatcaaa gatttttgat tcctttataa
    28201 gtaaatcaga agattttaat gcttttttta tttttgatgt agaaacgttt ttgtaatcac
    28261 cacttgaaga acaactaacc attcctaatg ataagattat cgaaaaaaac aatattaaaa
    28321 tttttttcat gataaacctc caagtttttt aaactctgtc ttaaattagt ttactacata
    28381 attatataaa aataaatgta tttaatgtta cagttttgat taataatgta atattttgat
    28441 aataatacct attgagaggt gattagaaat gagaatacca aaacatgtag gaattatacc
    28501 ggatggaaat agaaggtggg caagtcaaaa tggtatgaca aaagataaag gatatgaaag
    28561 tggaatagac cctggactag agtcttatag attatgtaga gatttaggct gtgaagaggt
    28621 gactttttat ggatttacaa ctgataatac aagacgtcca tcagtgcaga caaaagcttt
    28681 tacaaaagca tgtattgatg ctgcaaatat attaatagat gaaggtgctg ctttattagt
    28741 tgtaggaaat acaaaatctc caatgtttcc agaagaatta ttaccatata ctaatagaat
    28801 taaagccaaa gaaggtcaaa taaaagcaaa tcttctggta aattatggtt ggtattggga
    28861 cttaaataat atatcaggag tagaaaatgt aaataaaaat aatatacagg attacataca
    28921 gtcatttgat gtatccagac tagacttgat aatcagatgg ggtggaagaa ggagattaag
    28981 tggtttcctt cctgtacaat caatttatgc agatttttat gttatagata attattggcc
    29041 agattttaag agtgacgata taaaggacgc atttagttgg tatgatacac aagatgtcac
    29101 tttaggtgga taattaaaaa tattctgatt taaggttgta gagtgtttta aattattgaa
    29161 aaaaaaactt cttgatggta aaataacact aataatatgt aaaagtgtaa aaatttatac
    29221 caagaagggt gaagaaatgt caaaaggcaa taataacaat aattcaagaa acaaatctaa
    29281 aaagaccagt catctgaata gaaaaaagcg aaaattaaat aagaaaaagt tagcagtgtt
    29341 gatttgcttt acagttttat ttttatttat tgcatttaag gctactcaag gtgtagtagc
    29401 tttggtaaaa agtatggata aaagtaataa aactaatcaa caacaaaatg ttaactcaga
    29461 acaatttgac cttggtaatg aagaggaaaa taaaaagaaa aaatatactg tatttataga
    29521 cccaggtcat ggaggcaatg ataaaggaac tgaaagcaag accagtaata gatatgaaaa
    29581 agacctaaat ctacaaattg caaaaaaatt agcaaataaa ttatctaaac aaaaggatat
    29641 tcaagtagta gtatccagaa ctgatgatac atatatatca ttaaaggata gagctatctt
    29701 agcaaataat agttctgctg atgtgcttgt ttctattcat ttaaatgcag agaaaaatgg
    29761 taatacagca acaggtatag aaacttggta taggaataaa gctacagatg gttcaaaaga
    29821 acttgcacag acagtacaaa gtactatagt atcctatgtt aaagttagag ataggggaat
    29881 agttgaaaat aactttgaag tacttagaga atcaaatatg cctgctatat taatagagtg
    29941 tggtttttta acaacacctt cagaggaaca aaaaataata aatgaaaaat atcaagacca
    30001 acttgcggaa ggaattgttc aaggtgtact ttcataccta gattctaaag ggaataagta
    30061 agttaacttt actttaatgt gaggataaat ttaaaagttt aactgtgtaa attgtattaa
    30121 ctttatttcg taatgttgca aacattgttt gaatttagaa actatgaaat tagaaattat
    30181 tttatctata tctaatttca tagttttttt tgcaaaaaat ttatagttat aaaattttaa
    30241 aaaataaatt tagtataatg taatgtagtt atttatatgt gattttaact tgcattgatt
    30301 tgctatcaat tgtgctttat aattagtata tataaagttt aactgtaaga taatttaaaa
    30361 aataggggaa tttatatgaa taaaaatagc atgacaagaa tttacagttt aaataaaata
    30421 atttttatta taattggaat tttaggaata gttttactca caagacatat tgaggtagat
    30481 attaaagttt taattttaat tttattaacc ttgtttagta taaatgtatt tatttcatat
    30541 cttaaaatta agttgtatga ggataaaatt aatttaggat tgataaataa ttcagataag
    30601 tttataaata ttactaaaga tgagaacttc ctaaaacatg ttcaaaatta tattatcagt
    30661 aatgaaaaag aaaactgtgt aatggcttgt tttgatttat gtagactcaa acttataaat
    30721 aatatatatg gttatgagct aggggatgaa gtgttaaata atattttaag taacttaaaa
    30781 aattattttg gaaaagaagc tatttatgga aagttaaaaa gtgatgtttt tgtattaata
    30841 ataaagcttg aaaataggga acagaagatt ccttatttag taaatcttat taagaataaa
    30901 attgtgatac taagtcagat tgacagtttt aaaatggata taaatattga ggcttctatt
    30961 ggaatttata aatttaacaa taatgaaatt gatataaaaa aagctataga taatgctgat
    31021 atggcaaggc ttaaatcaaa aggactaaag cacatagagt atgtagaatt tgataatgct
    31081 atggaagaag aaatacaatc aattatgaaa atagagagag atttattctt ggctattaaa
    31141 aataaagagt ttgtaattca ctatcaacct aaagttgatt caagtacagg taacattata
    31201 ggttcagagg cattgataag atggttgcac ccatcattag gcatggttgg accaaataag
    31261 tttataccta tagctgaaaa aaatggtctg ataaacaata ttggtagatg gctaattcaa
    31321 gaagttttta ttaccattaa caagtggatt tcagaaggta taaatgtctt accagtctca
    31381 ataaatcttt ctagagtaga actatataaa aatgatttag ttgatttttt taaactgatg
    31441 tttaatacat ataatattcc aaaagaactt atagaattag aaattacaga aacgacagca
    31501 ctaagagatg taaaatttat aagtgaaagg ctttatgaga ttaaatcttt aggtatgaat
    31561 atatcattag atgattttgg agtaggtaat tcaaatttta tcaatcttaa ggggatacca
    31621 ctagatatta taaaaattga taggtcactt atattggata tagttacaaa tacaaaaaca
    31681 aagtttatgg tgaaagcaat tgttaacctt tcacatgatt taaacgtaac tgttatatgt
    31741 gaaggggtag aggatatgca tcaggtcaaa gtcttaagtg aactgggatg taatttcata
    31801 caaggttatg tattttttaa acctttggat gagatgaatt ataaaaaact tcttactgac
    31861 ggaagttata taaatctgaa agatactctt ttagataaat gcatgacagt tgaggaggag
    31921 taaggatgat ttcagaagat gtagattatt caataagaat cataagagct atatttaata
    31981 atggagaaga taaaccaata gatgctaaaa tgatattaaa aagtgaagat ataccaatac
    32041 taacactata tagactgctt agaaagcttt gtgcaaacaa tattcttact tttaacaaag
    32101 aagatggcaa gacatacatg ttaaatgtgt cattggatac aataagtcta agaactattg
    32161 tagaagtaat tgatggaaaa atatatataa ataaatgtac gagatatgta tctaattgca
    32221 gtaattgctt aaaaggttgt aaagtaaatc gtgaattgct agaaatagaa aaagaaattt
    32281 ataaactttt atcgagaaaa tctataagac aaatactaga ataaaaaatt ttcagctatg
    32341 ataataattg gaggttttcg gttatggatg atatatctca agataatttt ctactgtcta
    32401 aagagtatga gaatagctta gatgtagata ctaaaaaagc aagtggaata tattatactc
    32461 ctaaaataat tgtagattat attgtaaaaa aaactttaaa aaatcacgat ataattaaaa
    32521 atccatatcc acgaatactt gatatttcct gtgggtgtgg aaattttctt ttagaagtat
    32581 atgatatttt atatgactta tttgaggaaa atatatatga attgaaaaag aagtatgatg
    32641 aaaattattg gactgttgat aacatacacc gtcatatatt aaactattgt atatatggtg
    32701 ctgatattga tgaaaaagct ataagtatat taaaagatag cttaacaaat aaaaaggtag
    32761 taaatgattt agatgaatct gatataaaga ttaatctatt ttgttgtgat agtcttaaaa
    32821 agaaatggcg atataagttt gattacatag tgggtaatcc accctatatt ggtcataaaa
    32881 aacttgaaaa gaaatataaa aaatttctcc tagaaaaata tagtgaagtt tataaggata
    32941 aagctgactt atatttttgt ttttataaaa agattataga tattttaaag caaggaggga
    33001 ttggcagtgt tataactcca agatattttt tagaaagtct atcaggtaaa gatttaagag
    33061 aatatattaa atcaaatgtc aatgttcaag aaatagtgga ttttttaggt gcaaatatat
    33121 ttaaaaatat aggggtatct agttgtattc taacttttga taagaaaaaa acaaaagaga
    33181 catatataga tgtatttaaa atcaaaaatg aggatatatg tataaataaa tttgaaacat
    33241 tggaagaact tctaaagagt agcaaatttg aacattttaa tataaatcag agattgctat
    33301 ctgacgaatg gatacttgta aataaagatg atgaaacttt ttataataag atacaagaaa
    33361 aatgtaaata tagcttggaa gatatagcaa taagttttca aggaataatt acagggtgtg
    33421 ataaagcgtt tattttaagt aaagatgatg taaagttgaa ccttgtagat gataaatttt
    33481 taaaatgttg gataaaaagt aagaatataa ataaatatat attagataaa agtgaatata
    33541 ggctaatata ctcaaatgat atagataatg agaatacaaa taaaaggata ctagatgaaa
    33601 ttatagggct atataaaaca aaattagaaa acagaagaga atgtaaaagt ggaataagga
    33661 aatggtatga acttcaatgg ggtagagaaa agcttttctt tgaaagaaaa aagataatgt
    33721 atccttataa atcaaatgaa aatagatttg ctatagatta tgataataat ttttcaagtg
    33781 cagatgtata ttcttttttt ataaaagaag agtatttaga taaattttca tatgaatatc
    33841 tagttggaat tttaaattcc agtgtttatg ataaatactt taaaataact gctaaaaaaa
    33901 tgagtaaaaa tatatatgat tactatccta ataaggttat gaagataagg atttttagag
    33961 ataataatta tgaagagata gagaatttat caaagcaaat aatatcaatt ttattaaata
    34021 agtctataga taaaggaaaa gtagaaaaat tgcagataaa aatggataac ttgataatgg
    34081 attctttagg tatataagca gttgtaagta ttaaaaaatt ataatctttt aattgtttat
    34141 ttaaatttag aaataaaaag ttagccatat aaaaaatatt aaaaatatat acttttcaat
    34201 atttttttga taaaataaga atgaatttgt gcaattttat ttttctccaa taactaaaaa
    34261 tagttttttg aattaatatt tgcttaagaa taaaaatcag aaacgttttt gatatagtag
    34321 gtgataatat gaaaggatta gttttagaag gtggaggaac aaaaggagcc taccaaatag
    34381 gtgcatataa agctttgaga gagcttggta tagagtttca aggagtaact ggcacatcaa
    34441 ttggtgcttt aaatggagca tatataattc aaaatgatat tgaagtaatg gaagatattt
    34501 ggttaaatta tgactatact cattttatga atattgatag agaaacctat gagaggttta
    34561 aaaatgtaga tttcactact aaaaatctca atgcagtgtt tgagcttata aataaagcta
    34621 gaaaaaatga aggtatagat ataagcccat taagacaact aatggagaca acattaaatg
    34681 aagacataat aaggaaatca aaaaaagact ttggacttgt tacggtctgg tgggataaaa
    34741 aaattaatcc atatccattg tatatcgaag atatacctaa aggaagattg attgattatt
    34801 taattgctag ttccagtttg cctatttttc aaacgaacat gatggatgat aagttgtatc
    34861 ttgatggaat gttttgtgat aacatgccaa taggactctt ggaagacaaa ggttatgaag
    34921 atgttgttgt aattaggttg attgatgatt ttattgggaa aatgaatcta aatcgacatc
    34981 aaaatataaa tataaaaact ataataccat cagaatatct aggaggttct cttaataaag
    35041 atagagataa tgtagaaaaa aacatccgac taggttactt agatactatg aaagcatatg
    35101 aaagatgcac tggaattaag tattattttg atgtagagta taaatataat gaagaatatt
    35161 gttttgataa atttagaagt atgagcaatg aaacaataca atatatctgt aatttattga
    35221 atataaaaag agatgcttca cttagaactg ttatggaaag tgtaatacca aagcttggtg
    35281 aggtgcttgg attgccaaag gatttttcat ataaagattt gttttactgt atatatgaaa
    35341 agaaacttga agaaaataat ataaacagga taaaattata tgattttaac aaggttatag
    35401 atgttgtaaa tacaaatatt gattctaata gaaatttagc ttctaatttt gaagttagac
    35461 ctaaaattag tattaaaaag aacaaaaaca caaaattatt gacaaattgt attataaaag
    35521 acataaaaaa tcaaagttaa ataaaaaaca aaaaaaaaat ttgtaattat actcgaaaaa
    35581 agtgtatatt agtagtataa tatttttgta gcactagtgg gaacaaaaaa tgaccatagg
    35641 acaaaaaagt accacttagt accattaaag taaaaaacag gaaaacaatt ttaaaaaata
    35701 taaaatgtaa agtttatagg aggatttaaa aaaatggaaa aagtagttag tatcaaaaat
    35761 gcaagtggat tacatgctag accagcagga atgtttgtta agaaggcagc tgaatttaaa
    35821 tcaacagtag aggttgtagc aaaagacaaa actgtaaatg caaaatcaat aatgggaata
    35881 atgagtttag gtttagctca aggagaagaa ttaaagttag ttgtaaatgg agaagatgaa
    35941 gaagtagctt tagctgcaat ggttgaatta gttgaaagtg gatttggaga atagatataa
    36001 taatttttta aaaatttgat atttagaatc taatattact taaagtaaag taacagagaa
    36061 gtattaaaca tatacagacc aacatttgta gatatttaat ttctttgtta ctttcatgtt
    36121 tatttaatca gaagattaag actattgtta attgggtata aaaatataaa tattttagaa
    36181 aatgaaataa gatattttta atcataaatt cagagtaaaa atacagtaac aaatagttta
    36241 taaaatttta taaaaaatta taagtaaata aaactataaa aatgtaaatt atttatataa
    36301 atttataaag tttatgtgct agatgatatt ttttaggagg tagggttatg gcttacaaag
    36361 gaataggtgc ttctcctggt gttgctttag ggaaagcgtt agtagttgaa catagtgaat
    36421 tagtaattga aaaaaaatct atagataatg ttgaagctga aattgctaaa ttagaagatg
    36481 cagttgcagt ttctaaagaa gaattagtaa aagttaagga aaaggcttct gaagaattag
    36541 gagcagagga agcagaaata tttgaagcac atttattagt tttagaagac ccagagttaa
    36601 ttggttctgc aatagataaa attaaaactg aaagtgtaaa tgcagagtat gctttaaatg
    36661 aaataaaaga gatgtttgtt agcatgtttg agtctatgga caatgagtac atgaaagaaa
    36721 gagcggcaga tataaaagat gttacaaata gaatacttag acatatatta ggaattaaag
    36781 ttgttgattt atctgcttta agcgaagaag ttgtattaat agcacatgat ttaactccat
    36841 cagacacagc aactatgaat aaaaaaatgg ttttaggatt tttaactgat ataggtggaa
    36901 gaacttctca tactgctatc atgtctagaa ctttagaaat agctgcaatc gttggattaa
    36961 atgatataac ttcaaaagtt aaggatggag attttgtggt tttcaatgga gacacaggtg
    37021 aagtaatcgt gaatcctgat gaagagacta taaataaata tactgaatta aaagctaagt
    37081 atgaagatga gagaaaagca ttacagctat taaaaggaaa accatctgta actttagacg
    37141 gaaaacatgt ggaattagct ggtaacatag gaacacctaa cgatatagaa ggtctaataa
    37201 agaatgatgc tgaaggtgtt ggtctttata gaacagaatt tttatacatg gatagagatt
    37261 ctttcccaac agaagaaata caatatgaag catacaaagc tgtattagaa ggaatggatg
    37321 gaaagcctat agttataaga acattggata taggtggaga taaagaatta agttatttaa
    37381 gtatggaacc tgaaatgaat ccattcttag gttacagagc aataagactt tgcctagata
    37441 gaaaagatat atttaagact caattaagag ctttatatag agctagtgtt catggaagat
    37501 taagaatcat gttcccaatg atttcatctt tagaagagtt gttacaagct aaagaagttg
    37561 taaaagaagt tttagcagaa cttgattctg aaggtgtggc ttatgctaaa gatgtagaaa
    37621 ttggtatgat gatagaagtt ccatctgctg ctgtaatatc tgatgtattg gctaaacacg
    37681 tagatttctt ctctatagga actaatgatt taattcaata cacttgtgca gttgatagaa
    37741 tgaatcaaaa gataagttat ctttacaatc aatttaatcc agctgtttta agacttataa
    37801 agactgttat agacaatgca cataaagaag gaaaatgggc aggtatgtgt ggagaatctg
    37861 ctggagacca aaaaatgata ccaatacttt taggtatggg attagacgaa ttctctatgt
    37921 ctccaatatc aatacttcct gctagaaagt taataacttc agttaaagag tcagatatga
    37981 aaaaattagc tgatgatgta cttaatatgg gtactgctga agaaataaaa aactatatag
    38041 aaaagacttt taatatataa ttaatgttat atagttacta aaattcattt ttctaaataa
    38101 caaaattata ttttacgaat aaaaaaacta tagtatatca tatatactat agtttttttg
    38161 ttatataaat tacgtatcaa aatttgtaaa atgaatagat ataattacta aatatgtgat
    38221 agtattggct ataataggat ataaaaaata atattgtaat aaaaagttta tatttagtaa
    38281 tgaaaattta acgttttact tgaaattatg tgttttgtaa tgtattatta aggttctaat
    38341 aggaacattt tcatcaattt ttctatagtg ggggtaggaa ttatgaggta caaaaaaaga
    38401 aatatagata agtcaagtga actttcattt caatctctag caaaatattt tataactttc
    38461 tatatagtaa ttatattaat tattctttct atgttttgta taaatacaat atgggttatg
    38521 aaaaaagata atcaagattt attatctaca acatcaaatc gtattgaaga tagggtagga
    38581 gaaacaatta agctattgaa ctctttgagt aaagataatt acataataga taatagtgtg
    38641 aatggcatag ataaaagtaa agaactttca atgtatagtg atgaatttgg gtatatgatg
    38701 atatgttttg ttgataagaa tataattgta tgggatgaag aaggtggtaa tattagtcta
    38761 gctggtcgtg attatatgca gaaacttttt gcaacaaaaa aatatcaagt tacagatagt
    38821 tttgcagcag gggctgatgg aaaaacttta aactacacta ttgcatcacc tataataaag
    38881 aatggaaatg tagatggttg tgtatttgca gcaatttact ttgatgagat aaaggatata
    38941 ctcaaacaag gaaaaggtca acagcaacag aatttcatat tatttggaag tgaaaatcaa
    39001 ataatgaatt taacaagtga tgaaactgca tatggagaga agtatatgaa gttatcgcag
    39061 aaaacaaaat atcttggaac caatgcaaaa aaagtagaaa aggatatgtt taataataaa
    39121 tcaggtgatt attgggcttt tgaaaatgga aaattatact ttatgtccta taaaccaatt
    39181 aagaacacaa attggagttt attttgtaaa gttaatttct tagatatttt tgcattaaat
    39241 ttaattccta tgggagctat tctatctgtt ataactttag tatttattat tttgatttgt
    39301 atggagaaaa gcttcatgaa aaaacgaatg gaagttattg atatgctttt aggttctgtt
    39361 caagaattag aaaaacgtat atatcaaaca gaaagaccta gtgaagtaga ctttaaagaa
    39421 attattcagc tcacaagtaa aggtctgact gatggattaa ctggtgttgt aacacgtact
    39481 gtattttttg accaaattta taatcgtgtt gaaatggagg aaaatgataa attatctgta
    39541 atttcatttg ttgatttaga tgatttgaaa tgtattaacg acttatatgg acatgaaatt
    39601 ggggatatgg ttttgaaaaa tgttggatat gtacttcgtg aatatgagat aaaatataat
    39661 ggtttaattg ggcgctatgg tggagatgaa tttgttatgt tgttatctgg ttttacatcg
    39721 agagaagagg tggagaattt attggatgag attgctattc gcttacatac tgaagtacta
    39781 acagatgatg gtatcattca aactcattgt agtgttggag ctgtagtatg tagtgtaaaa
    39841 gacaataaag atatagataa tttattaaaa caggctgatg aagctttata ctatgttaaa
    39901 cgtaatggaa aaggtaatta tcatttagtt taatgtatgt ggaaggagtt tatatcatat
    39961 gaaaaatgta tctaaaaaat tttttgtatg tactattatt gtattaataa catttttatg
    40021 ttttagtaaa tttgctattt atgtttttga caaacaagaa aagaaagaaa caaaagtagt
    40081 agaaaacatg ttaaatgtct acaagaataa cattatttta aatctgactg aaaaatttaa
    40141 ttatagcaaa gacttgacat cagttttagt ttcaaacaat tattctatag ataaattaaa
    40201 acctattgca gatgaaattc ttaaaaacaa ttcttgcata tatatttcag ttgtagaaaa
    40261 atataatgta gctgcatttt tttctaattc tgtcaaaaaa gatattatca atactccaat
    40321 acaggaactg aattattctt attcattagc aaattctatc aaaggattag tcgtagaagg
    40381 tccttctaaa gaccagtttt caaatggaga tgtgttttta attactaatc ctatttataa
    40441 aaatggagag tactggggag aaattacagt agctttagat gccaaaaaag ttgtagattc
    40501 ttttaactta aataaattaa aagaatctgg atttgagtat gaactttggc gtgtacacct
    40561 agataatggt tcaaaatcta caatagaaat ttctactaaa gattttaatt tttccaaatc
    40621 acatgaaatt aagtttaaac ttccgactgt ttggactctt agcattgtgt acaaaaatgg
    40681 atggaataat aagaatatag attttattgt atttgttata ttgttaatta tttccatatt
    40741 aataggtgtg atgacattta tttacattga aaagaagtcg attagtaagg aattaaatca
    40801 acagagtctt aaaaatttag aaactggtat tttgaataga gaaggttttt taattaagtt
    40861 acaagagcat ctgaatagaa aaaataatga aatagtgttg ctgtatatat gtattactaa
    40921 ttatagtaaa tttgctccag ttatgagctt tgaaaaaaga caagattatc ttacacatat
    40981 agtaaaaaat ctagataatt acataaaaag ttctcatttt attgctcgta taagtgagga
    41041 aggttttgtt ctagctttag aagaaaattg tgataaaaat gaattgctta acattgaaaa
    41101 agggatttcc ttagagcttt tacgaaaaat taaagtagaa aataaacaag tatttttaac
    41161 gattggttat ggctcatcta ggtgtgttga tgatagaaaa gatgcagaat ctctgttact
    41221 ttcagctatt gaagattatg agagaagatt tccagcaatg tctcctattc atgattttac
    41281 taaaaagtgt gaagatatgc ttgatgaaaa gaaacagatt gtatttggtg aatatccaga
    41341 tttagaaata aacaagttgt ctaaagtaat atacaaatat tataaaaaag tacagcgtat
    41401 tatgtataaa gattataata ttgatattgg aaatagacga gggtatatgc gtgatgtcga
    41461 agtattaatt gattataatt ctgagagaat gttatactta tttttaatag acatatgcaa
    41521 gtttggaaaa tttaatgaac tgttttctat tgaaatagga gatgttattt taaaagaagt
    41581 tagtaacaaa ttaaaaacaa ttttttctaa ttatctatat cgtattaatg gagatgtatt
    41641 tttaggcatt tcaatagata aagaatctta cttagatact ttacataagg ttaatgaagt
    41701 atttaatagt tctttaagtg tagaagatgt actttttgat gtaaaatgta atattggtat
    41761 ttgtcaatat ccatatcatg gtgaaaatcc atatgacctt ctggaaaagg tacaaattgc
    41821 attggagtat gcaaaaaagg atgtcaaaag taatgttaaa gtttatgata aggaattgac
    41881 agaagagatt taccatgaaa ataatattat taaggattta aaaaaaggtc tggaagaaca
    41941 aacactagaa gtttggtatc agccaatttt taatgttagt aaaaactgtt atataaaagc
    42001 tgaggcacta attagattga gaaataaaga gggcggttat tattctgcct atgaagttat
    42061 tacttatgca gaaaagcatg gacttattaa ggatgtaggt ctatatgtac taaaaaaggc
    42121 ttgtgatgta actacaaaaa taaaagataa aaatatagat tttgaacaaa tgcaattaaa
    42181 tttatctgtt cagcagattg tacataagca gtgtgcaaat gacatattat catgtattga
    42241 gaattgtggt ttagataaaa agtatatttg tgttgaagtt acagaaacag tacttatgga
    42301 aacttttgaa attgtaaatg ttactcttga taaactaaaa aaagaaggca ttagcatagc
    42361 tttagatgag tttggttctg gatttagtag tataaattat ctggcaaatt tacctattga
    42421 aaatttaaaa atagataagg aattagtaga acaaattacc tattctaaaa aacaatttga
    42481 attattaaaa actatagttc aaattgctaa gattaatggc atggatattg tagcagaagg
    42541 tgttgaaaca aaagaaactc tggatttagt tgtaacttca ggtgtgaatt tgattcaagg
    42601 tcattatttt tcagaacctt taagtgaaga taaatttatt gaacttatga ttgaagaata
    42661 aaggttaata aaataaagat ttaaggtatt gaaaaataat taaaagtatt taataataga
    42721 attagggaag aataagttta taattaaaaa taattgatta gtagttaata aaataaatgt
    42781 gatatccaaa taaatcctaa atctaatttg agttttaata tagatagtct aaagtttgat
    42841 tattaaagat ttaattgtaa gttgttacag ttgatgatat tgattagaga ttaaagttta
    42901 gagtagaaag ttaccttaaa tttaaaaatg caagataacc caatctaaaa attataatca
    42961 ctcaataggt ttaaggattt atttgtttat tataaatagg agggtgtctc aaaatgaact
    43021 ttttagttta tgaggcactc tcttttatat agaattaaat atattttatt atttcaacaa
    43081 tgaaaaagaa gcttatctct attttgagac agcctctttg tatactatta ttaatttaat
    43141 caataatata atttaaaatt ataatattag ttaagatttc ctgctttatt agtaaataat
    43201 tctttaatag cattgtttct ggaaactaaa tcgttatcag agttgtttgt ttttttcata
    43261 atcactgaat aacgtttttt atttataaaa aatattaaaa tcttatcatc atcaaaattg
    43321 tattctttat atctgtcaat agactcataa cctagattta gaatgttttt gtcttttata
    43381 ctatctacat ctaaaatata tgatgggtca gcctttagta atatattaat taaacatttt
    43441 tcttcaccag cacagaataa ctccatctta cttgatatag atttagattg ttctgaagtt
    43501 atttttgcag gaataaggtt gtcattatca tctcttagaa gataaccatg tgtgtcttgt
    43561 tgatatacta aattaacctt tttcttagga acactaatca ttttatctaa atgtacataa
    43621 tgatgatttt caacaaaacc ttcatttaat atttcaacaa agttattaat tttacctagg
    43681 caaaaagatt ctatagattc tttacagaat ttatttgtaa atggtattat gtttacgttt
    43741 tcctcgtctg tattccatgc tatagcataa tccaacgaat atacttcttc ctctatatct
    43801 gcaaaattat attgtactat gtttcctttc aaaattactc gacctccatc ttataatata
    43861 tttaat
//
LOCUS       DAEQAF010000022        43625 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.023, whole genome shotgun sequence.
ACCESSION   DAEQAF010000022 DAEQAF010000000
VERSION     DAEQAF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43625
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.023"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            284..748
                     /locus_tag="KRN00_001321"
     CDS             284..748
                     /locus_tag="KRN00_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBH1827188.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            755..1249
                     /locus_tag="KRN00_001322"
     CDS             755..1249
                     /locus_tag="KRN00_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBH1827189.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNAFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            1265..2290
                     /locus_tag="KRN00_001323"
     CDS             1265..2290
                     /locus_tag="KRN00_001323"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBH1827190.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYTFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            2277..4724
                     /locus_tag="KRN00_001324"
     CDS             2277..4724
                     /locus_tag="KRN00_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBH1827191.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            4904..6277
                     /gene="radA"
                     /locus_tag="KRN00_001325"
     CDS             4904..6277
                     /gene="radA"
                     /locus_tag="KRN00_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBH1827192.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            6280..7350
                     /gene="disA"
                     /locus_tag="KRN00_001326"
     CDS             6280..7350
                     /gene="disA"
                     /locus_tag="KRN00_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBH1827193.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            7439..8533
                     /locus_tag="KRN00_001327"
     CDS             7439..8533
                     /locus_tag="KRN00_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBH1827194.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            8662..10839
                     /locus_tag="KRN00_001328"
     CDS             8662..10839
                     /locus_tag="KRN00_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827195.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TIYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVVFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(11025..11870)
                     /locus_tag="KRN00_001329"
     CDS             complement(11025..11870)
                     /locus_tag="KRN00_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1827196.1"
                     /translation="MNRNNFSHEIIEPIDNLDVNFKLFDDSGSYVANHWHNSLEIIYI
                     TSGDLQINMEGYTYNLKANECMFINSGIIHSTRCIYQNTSILLQVPLSFLNKYIPDFK
                     NCYFDFKVNANDNNYKKNSSKVKLILENMREIKLSSPPAANLLFTSLLFELLFELYTN
                     FKISVGNKNMKKTVLDLSKFEPVLEYTKINYKMPISINKIAKVAHLQPEYFCRKFKQY
                     MGQTYLEYLNDVRISHIYKDLINTNDTLCSILEAHGFTNTKLFYRIFKEKFKCTPKHI
                     RKKST"
     gene            12087..13253
                     /locus_tag="KRN00_001330"
     CDS             12087..13253
                     /locus_tag="KRN00_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBH1827197.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SKIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            13275..14921
                     /locus_tag="KRN00_001331"
     CDS             13275..14921
                     /locus_tag="KRN00_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBH1827198.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMKWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYVQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            15018..16391
                     /locus_tag="KRN00_001332"
     CDS             15018..16391
                     /locus_tag="KRN00_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1827199.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWTKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGPINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQNYIG
                     VISASAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            16836..17789
                     /locus_tag="KRN00_001333"
     CDS             16836..17789
                     /locus_tag="KRN00_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBH1827200.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            17827..18789
                     /locus_tag="KRN00_001334"
     CDS             17827..18789
                     /locus_tag="KRN00_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBH1827201.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            18814..19800
                     /locus_tag="KRN00_001335"
     CDS             18814..19800
                     /locus_tag="KRN00_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBH1827202.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            19813..20859
                     /locus_tag="KRN00_001336"
     CDS             19813..20859
                     /locus_tag="KRN00_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBH1827203.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTAKETIVSTNTSKSSE
                     KKELKIENENSSMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            21026..22756
                     /gene="lpdA"
                     /locus_tag="KRN00_001337"
     CDS             21026..22756
                     /gene="lpdA"
                     /locus_tag="KRN00_001337"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBH1827204.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDTV
                     KENQNIEVKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     ELDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPIDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            23174..26122
                     /locus_tag="KRN00_001338"
     CDS             23174..26122
                     /locus_tag="KRN00_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827205.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPNGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPLEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            26100..26564
                     /locus_tag="KRN00_001339"
     CDS             26100..26564
                     /locus_tag="KRN00_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1827206.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            26644..26946
                     /locus_tag="KRN00_001340"
     CDS             26644..26946
                     /locus_tag="KRN00_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1827207.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            27008..28372
                     /locus_tag="KRN00_001341"
     CDS             27008..28372
                     /locus_tag="KRN00_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1827208.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVIFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            28407..28880
                     /locus_tag="KRN00_001342"
     CDS             28407..28880
                     /locus_tag="KRN00_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827209.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YLKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            29052..29702
                     /locus_tag="KRN00_001343"
     CDS             29052..29702
                     /locus_tag="KRN00_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH1827210.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREDINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            29876..30808
                     /locus_tag="KRN00_001344"
     CDS             29876..30808
                     /locus_tag="KRN00_001344"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1827211.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYHDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKDRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            31082..31795
                     /gene="ispD"
                     /locus_tag="KRN00_001345"
     CDS             31082..31795
                     /gene="ispD"
                     /locus_tag="KRN00_001345"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBH1827212.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            31792..32277
                     /locus_tag="KRN00_001346"
     CDS             31792..32277
                     /locus_tag="KRN00_001346"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBH1827213.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    32372..32580
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            32644..34359
                     /locus_tag="KRN00_001347"
     CDS             32644..34359
                     /locus_tag="KRN00_001347"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1827214.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLVSQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            34481..35926
                     /locus_tag="KRN00_001348"
     CDS             34481..35926
                     /locus_tag="KRN00_001348"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1827215.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            36366..37847
                     /locus_tag="KRN00_001349"
     CDS             36366..37847
                     /locus_tag="KRN00_001349"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBH1827216.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            38068..38223
                     /locus_tag="KRN00_001350"
     CDS             38068..38223
                     /locus_tag="KRN00_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827217.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            38368..39765
                     /locus_tag="KRN00_001351"
     CDS             38368..39765
                     /locus_tag="KRN00_001351"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBH1827218.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLDMG
                     IVLEDTRQGVKWKRI"
     gene            39750..40163
                     /locus_tag="KRN00_001352"
     CDS             39750..40163
                     /locus_tag="KRN00_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBH1827219.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            40269..41027
                     /locus_tag="KRN00_001353"
     CDS             40269..41027
                     /locus_tag="KRN00_001353"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBH1827220.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLKEVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            41040..41777
                     /gene="rlmB"
                     /locus_tag="KRN00_001354"
     CDS             41040..41777
                     /gene="rlmB"
                     /locus_tag="KRN00_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBH1827221.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            41780..42307
                     /locus_tag="KRN00_001355"
     CDS             41780..42307
                     /locus_tag="KRN00_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBH1827222.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            42372..43019
                     /gene="sigH"
                     /locus_tag="KRN00_001356"
     CDS             42372..43019
                     /gene="sigH"
                     /locus_tag="KRN00_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBH1827223.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            43093..>43625
                     /locus_tag="KRN00_001357"
     CDS             43093..>43625
                     /locus_tag="KRN00_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBH1827224.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSAL"
BASE COUNT        17865 a         4536 c         8188 g        13036 t
ORIGIN      
        1 tttttattat tatttttaca aatgtttagt aataaagatg agaaggtata tttaaaatat
       61 aaagtattta aagttctgaa atctaatcat gaagcaaaaa attagcattt ggttatcaat
      121 aaatataata aataaaaact cataattaat gaaagaataa attcatatct aaatttctat
      181 aaaaaattta aatttataca atttagggct ttaaaaattt aaataatagg tgtaaaataa
      241 tagtcaaaga aagtcaaaaa taaaaaggtg tgtggtgata ttaatggcaa ctatgacaga
      301 tataattgaa aaatttatta aagatttgat ggaagaagat aatagcatac aaattcaaag
      361 aaatgaacta gcaaacttgt ttagttgtgc accatcacaa ataaattatg tcttaacaac
      421 aagatttaca atagatagag gatattacat tgaaagtaaa aaaggtggcg gaggatatgt
      481 tcaaatagaa aaaatacgaa aaagtaaaga tgggcatatt agagaactac taaatgaaaa
      541 aataggaagt cagatatcct ataaaaaagc aaaggaatta ttagaaggtt taaaagagtc
      601 ggatttgatt aacgaaagag aattaaaatt aatattatat gcaatagatg ataaatcatt
      661 gtgtatgcca atatatgaat taaaagagaa ggtaaggtct aatattttaa agaatataat
      721 aataggatta tttagtatag aggagtgata atttatgcta tgtcaaaaat gcaataagaa
      781 taaagcatct gtatattata ataagatagt caatggagaa aaaacagaga tgtatttatg
      841 tagtgagtgt gcaaaagaga atacagaaat gaattttaac ttagatatgc ctttttcaat
      901 gatggatata ttttctaatt taggttttca acctaaaaaa gaacttgagg aaaagctagt
      961 ttgtcctaaa tgcaatacaa catatagtga gtttaagaat aatgggagat ttggatgtag
     1021 tgaatgttat aatgcattta gtagtcaagt aaatccaatg cttcaaaata tacatgggca
     1081 tatagaacat acaggaaaag cacctaaaaa atctttttat aagataagtg tagaaaatga
     1141 gattaaagaa ctaaaagaag atttagatag agctataaaa aatgaagagt atgaattagc
     1201 agctcaattt agagataaaa ttaaatattt aaaaggttct attgactaag attggagtga
     1261 tattatgaaa gagaacatag tcatgaaatc aagagttagg ctagctagaa atttaaataa
     1321 ctatccattt ccaaataaat tagataaaga atgtgccatg gaaataatag aaaaagtaaa
     1381 aaatgcgttt attaattcta acttagaaca aaaagaagaa tttgatttct ataaaattga
     1441 agatttagac caatctaaaa aaatgcttat ggttgaagaa catataataa gcccagattt
     1501 agcagaaaat gataaaagtg cagttatagt aaaaaaagat aaaactataa gcataatgat
     1561 aaatgaagaa gaccatataa ggatacaaac tatatgtgat gatttaaact tagaatatgc
     1621 atatagtgta gcaaatgaaa tagatgattt gttagaatca agtttagaat atacctttaa
     1681 cacaaagcta ggttatctaa catcttgtcc aactaataca ggaacaggaa tgagagcttc
     1741 tgtaatgatg catttaccag cattaagtca actaggctat atggatgaac tttataaaat
     1801 ttcatcacaa ataggtatag caattagagg gatatatgga gaacgaacag aagcattggg
     1861 aaatatatat caaatatcta atcaacttac acttggaaga acagagtcta atattataga
     1921 aaatgtaagt ggacttacaa aagatgcaat ttcaaaagaa ataaaagcta gagaaatatt
     1981 gcaaaaaaaa ttaggtataa aactagaaga taaaatattt agatcgatag ggacacttga
     2041 aaattcaaga gtaatgagta gcgcagaggc aatgagccat ctatcaaata taaaaatggg
     2101 aatagaaatg aactatatag ataaactaga tttaagggct atagaacaac ttatgatagg
     2161 tatacaacca gcgcatcagt caataatgta taagagtgat gatgttgaga atagagatat
     2221 aaatagagca acatatatta gagaaacttt ggaaaaatta agaggaggga tgaattgtga
     2281 acttcaatag atttacacaa agagctaaaa aggcaattga tttagcgttt gaatctgcta
     2341 aaagtctagg acacaatatt gtcggaagtg aacatatact tttaggtctt ttaagagaag
     2401 aagaaggtat agctgctaaa gttctaagta aagttggatt tacagaagct tatttagaag
     2461 gcaaaatagt tgatatggaa ggtaagggag aagaaatctc agaagatata gtattaagtc
     2521 caaggagtaa acaaatactt gaattatcag gaatgtttgc aaataaatta aaaacaaatt
     2581 atattgggac tgagcatata ttattagcaa ttattcaaga aggtgaagga atagctaata
     2641 agattttaaa ttatgctgga gtaaatgata ggactttagc ccaattaaca attgatatga
     2701 tgggtattag tgataaaaat caatacaaag cagaaaatag ttacacgggc aaccagaatc
     2761 aagcagaatc taaagtactt gataagtatg gaagaaatct tacactatat gcaaaacaga
     2821 ataaaataga ccctgtaata ggtagagaaa aagaaataca aagagtaata caaatattaa
     2881 gtagaagaac taaaaacaat ccagtgttga taggagaccc aggtgtaggg aaaacagcca
     2941 tagctgaagg tctggctaca aatatagcct taggaaatgt tccagaaaca ctaaaaaaca
     3001 aaactttata ctctttagag atgggttcat tattggctgg ggctaagtat agaggagaat
     3061 ttgaagaaag aattaaagaa gttgtagatg aagttgttaa aaatggaaac ataatcttat
     3121 ttatagatga gatgcacaca ataatagggg ctgggtctac tggagaaggc tctatagatg
     3181 cttcaaatat attaaagcca gccttagcaa gaggagaaat acaagttata ggtgcaacta
     3241 caattgatga atatagaaag catgttgaaa aagattctgc tctagaaaga agattccaac
     3301 cagttatggt agatgaacca actaaagagg actcaataaa aatattagaa ggattaagag
     3361 ataaatatga agctcatcat aaagttaaaa taactgatga tgctataaag gcagctgtag
     3421 aattatcaac tagatatata tcagacagat atctgccaga taaagctata gacttgattg
     3481 atgaagctgc atcaaaagta agattaaaag aaaatacacc tccttcagaa ataaaaaaat
     3541 tagaactaga aatagaaaat atagataaag aaaaagaaga agcagtaaga tgtcaagact
     3601 ttgagaaagc agccaaaata agagatgaac aaggtctact taaaaaacaa ttagaagatg
     3661 ttagagaaag atggaacaag tcatctaaac attcagattt agttgatgga gaagttattg
     3721 ctgaagtagt gggcttatgg acaggaatac cagttaataa aattcttgaa gaagaggctg
     3781 atagactttt gagacttgag gaaatactgc acaatagagt tataggtcaa gaacaagcag
     3841 taaaatctat ttcaaaggca atcagaaggt caagagcagg tcttaaagac cctaatagac
     3901 caattggttc atttttattt ttaggtccaa caggagtagg taaaacagaa ttatctaagg
     3961 cattagcaga agtgcaattt ggagatgaaa atcaaataat tagaatagat atgtctgaat
     4021 atatggaaaa acatgctgtg tcaagaatga taggttcacc tccaggttat gtaggtcatg
     4081 atgaaggtgg tcaattaact gaaaaagtaa gaagaaatcc atattcagtt atcttatttg
     4141 atgagataga aaaagctcat ccagatgtat ttaatattct gttacaaatt ctagatgatg
     4201 gtagactaac tgattcaaaa ggaagaactg tagattttaa gaatactatt gtaataatga
     4261 catcaaatgt tggagcatct acaattggta gacaaaaaac tttaggattt agtatagcta
     4321 aaggagacga agaagaaaaa tctcaatatg aaaaaatgaa agaaaatata atgggtgaat
     4381 taaaacaaag attcagacca gagtttttaa acagaataga tgatataatt gttttccact
     4441 cactaaatga aaatcatata tcaaaaatag tacttttaat ggcagcgaaa ctacaagaga
     4501 gattaaaaga aatggatata aaattagaaa tgagtgatga ggctgttaaa ttaatttcta
     4561 aatctggatt tgacttagaa tatggagcaa gacctcttaa aagagcttta caaaaagagt
     4621 tggaagatga gctatctgaa gcaatcttaa aaggtaatgt gaaaaaggga agtaatgtag
     4681 tagcaaaagt caaagatgaa aaaatagttt ttgaaactaa ataatttaat agagttgcat
     4741 tttaaaatat tgcaaatata agttttataa tctaaacaaa attttaaggg caatgaatct
     4801 ataataattc attgtcctta attattttat ttaatcttta catattgtct ttcagatatg
     4861 ctaaaattat agtatagaat aaaaaattaa ggatgataaa agtatggcaa aaataaaaac
     4921 aaaatatgta tgtcaatctt gcggatatga aacagctaaa tggcttggta aatgtccaga
     4981 atgtacaaaa tggaatacat ttgtagaaga aatagaccaa aaaagcacca aaaaagaggt
     5041 ctttataata gataaatctt catctaaacc agtcagtata aactcaatag agagtaaaga
     5101 agaagagcgg tttacaacag atataaatga attagataga gtgcttggag gaggtatagt
     5161 taaaggctct ttagtgcttg ttggtggtga ccctggtata ggtaaatcaa cacttttaat
     5221 ccaagtatct agtaatgttg ccaatttagg aaaaactgtt ttatatataa ctggagaaga
     5281 atcagaatct caaataaaaa tgagagctaa aagattaggt attaactcag aaaatttata
     5341 tatatttgct gaaaataatt taagtataat tgaatcttat ttagaaagtg taaatccaga
     5401 attaataatt ctagactcaa ttcaaactgt cttcagtcca gaaatatcct cggcaccagg
     5461 aactgtcagc caaattaaag aaggtacttc aaaattcatg aaaatttcta aaaaaatggg
     5521 aatttcaacg ttcatagttg ggcatgttac aaaagaaggt tcactagcag gaccaaaatt
     5581 attagagcat atggttgata ctgttctata ttttgaagga gaaagatata atacttatag
     5641 attagtaaga gctgttaaaa atcgatttgg ttcaactaat gaacttggag tgtttgaaat
     5701 gagggattta ggattagtag aacttgataa tccatctaaa attttaatct ctgaaaaacc
     5761 aaaagatgta gcaggttcag taataatatc tactgtagaa ggtacgagac caatgttact
     5821 tgaattgcaa gcattagttt ctcctacaag ttttggtata ccaaaaagaa catctacagg
     5881 agtcgattac aatagagtag gtatgttatt agcagtatta gaaaaacgtg ttggtttgca
     5941 aatacaaaat caagatgtct atataaacat agttggagga ataaagataa atgaaccctc
     6001 aattgattta gggatagcca tttctgtagc atctagtttt agaaatatac cgatagatga
     6061 agatatagct gttacaggag aagtgggact tacaggagaa gttagagcag taagctttat
     6121 agaaaagaga atagctgagt gtaaaaaact tggatttaaa aagatagtag ttcctagaag
     6181 taattatgat gttgtaaaag agaccaaagg catagaaata tggccagtag ataacttaag
     6241 acaagctata aatatagtac ttgggaggaa tcaataaata tggagaattt tctagataat
     6301 aaaaatatgc tatatgcatt aaaaatgata tctcctggaa ctccacttag attaggtcta
     6361 aacaatgtac taagagctaa gactggtgga ttaattgtaa ttgcaacaaa cgaagatgta
     6421 atgaaaatag tagatggagg atttgctata aatgcagaat attcaccatc atatctatat
     6481 gaattagcta aaatggatgg agctatagtt ttaagtggtg atgtaaagaa aatattattt
     6541 gctaatgcac aacttatacc tgactatttt atagaaacat cagagacagg aacaagacat
     6601 agaacagcag aaagagtagc aaaacaaact ggtgctatag tcataggaat ttcacaaaga
     6661 agaaatgtta taacagttta tagaggaaat gagaagtatg tagtcgaaga tatatctaag
     6721 atatttacta aggcaaatca ggctatacaa actctggaaa aatataagac agtattggac
     6781 caagctgtaa caaatttaaa tgccttagag tttaatgatt tggtaactat ttatgatgtt
     6841 gcattagtca tgcaaaagat ggaaatggta atgagagtta caagtataat tgaaaaatat
     6901 gtgatagaat tgggtgatga aggaacttta gtaagtatgc aattagaaga attaatgggt
     6961 acaaccagaa tagaccagaa attaatattc aaagattata ataaagaaaa cacagaaata
     7021 aaagaactta tgaaaaaggt caaaaattta aattcagaag aactaataga attggttaat
     7081 atggcaaaac tattagggta tagtggtttt tcagaaagta tggatatgcc tataaaaaca
     7141 agaggttata ggattcttag caaaatacat agactaccaa cagcaataat agaaaactta
     7201 gtaaattatt ttgaaaactt tcaacaaatt ttagatgcat ctattgaaga attagatgag
     7261 gttgaaggaa taggtgaaat aagagcaaca tatataaaaa atggactcat aaaaatgaaa
     7321 caattagtct tattagatag acacatatga tgaattttaa atgaatttta ctactttttt
     7381 cttgaatata atatacactt tggtctataa tagataagta taactagggg gtgaagcatt
     7441 gataaggaaa gtaacaagaa tattgtttat tttacttgga tttacaatag gtataacaac
     7501 ctatttaaca ttaatgaaag attttgaaat attaacattt ggaaaagaaa catatggtta
     7561 tatcgcagct gtagtagcag gtataataat agccatttta ggatatctta tagaaccatg
     7621 ggttgtaaat aaagtaaaag aaattgctaa aatagtggat aaagaattgt caaaatatcc
     7681 tcagactgat atattgttag ggtctatggg tcttatagta ggatttgtta ttgcgtattt
     7741 attaagtgga ttagtaaata gaataccaat agtaggtgga atactatcct tactattata
     7801 tttattccta ggatatcttg gaatgaaagt tgcgcttaaa agtaaaaatg atttatttaa
     7861 tattggaaaa ctaggaagat tagcaaatcc tattaaggat aaagataagg ataaagaaaa
     7921 taaaaaagaa gtaaaagcca ttcctccaaa agtattggat acaagtgtaa taattgatgg
     7981 aagaatagct gatatttgta agactgggtt tatagaagga aaacttatta ttcctgcttt
     8041 tgttttggag gaactaagac atattgcaga ttcttcagat gatttaaaaa gagtaagagg
     8101 tagaagaggt ctggatatat taaatataat tcagaaagaa ttaaatatag aagttgaaat
     8161 aagtgagaga gactttgatg atatagcaga agttgatagt aaattattaa agcttgctca
     8221 ggttttaaat ggaaaagttg ttacaaatga ttataactta aataaagttg ctcaattcca
     8281 aggtgttgaa gtattaaata taaatgagtt agctaatgct ataaaaccag ttgctatacc
     8341 aggtgaagat atggttgttc aagtggttaa agaaggaaaa gaggctcaac aaggtgttgc
     8401 atatctagat gatggaacta tgatagttgt tgatggagga agaaaatata tgaatgagac
     8461 tataaaagta ctcgttactt ctgttcttca aactcctgca ggtagaatga tatttgcaaa
     8521 acctaaaaat taatatgttc aaagaaacct ataatttggg ctgtttattt taaatagatg
     8581 gtccaaattt atttatttat aacgataatg tttaatgtat tcttaaagat ggggatttaa
     8641 atcagaaagc agggagaatt tatgagaaaa aagattatat ctttcttagc aacatttatc
     8701 ataatattaa catcagcaag tcagtatagt tttgcagatg atatatcaac acgtggaaaa
     8761 gtaatattta tagatatgaa tagaactagt atgagtaata tgttaagaat aaaatcatta
     8821 agagaagaac tagacaatag agggtatatt ggcttgatga atataagagg cgataaagga
     8881 agtgatgata gaaggtcata tgctagtatg ggtgctggtg gtagagctaa tgtggctaat
     8941 gaagaagata ttaattttga aagctcgagt aaggatagaa atatagtttt tgaatcagct
     9001 acaggaaaaa gtgcaaaagg tataaataat ttaactataa ataagtctat aaatgaaaat
     9061 ttaaactttg gagagtatgg ttctgtatta gggtcattag gacaaagttt atctgataat
     9121 ggattaaaag catctgtatt gggtaattca gatataattg aaaatggtca acttataaaa
     9181 aatagaaact tatgtctaac tgcaatggat gaatatggaa gaatacctaa tggaaatgta
     9241 gatactataa ataaaaaaga cttatctatg ccttatggaa tatcaactga ttatgataaa
     9301 ttgattgtag agaccaaaga agcttacaaa aataatgatg tgatttttgt ggagcttgga
     9361 gacacatata gattagattt atataaacca aatttaaatg aaaaaacata tgagagtatg
     9421 aaagataaca tagaaaaaaa tatagatata tatttaaaaa atatattttc tatggttgaa
     9481 gaaaatgaca ctatctacat agcaagtgca tttccaagtg atttagatta taaaaataaa
     9541 agaagacttt ctccaataat aaaattaaat ggagaaggga aaggtatatt atcatcttca
     9601 actactagaa gagaaggtat tgtaacaaat ttagatgttg gggttgaaat attagacaac
     9661 tttaatataa aaaatcaaaa tatggttgga agaaaatatg aacttattaa cagagatgat
     9721 aataaagaat ttttgatgga tgaatatcaa aagatagtat ctatttcaag cataaggtct
     9781 acaatactga atggttttgt aagtatagtt ttcttgtcat ggatagttgc tatgattgca
     9841 attttattta gaaagcatat atcaaaaaat tataaagaaa caacattttt tatattaaag
     9901 gaacttttaa aaataggaat agtaatgcca ctgtcattta tgataacacc aataatgaat
     9961 ttcaaaacac cattagcaat atccttagga ataattataa taacacttac tatatatctt
    10021 ataagtaaag ttttaataaa gaacgattta aaaaacatgc tgttttttac tggattaacc
    10081 atagtaatta tggttattga tgctgggttt ggctcatatt taatgaaaag caatgttatg
    10141 agttatgatt gtataattgg agctagatat tatggagtag gaaatgagta tcaaggtgtg
    10201 gcaatcggta gtgcaatatt tacatttgca attttactta catataaaaa tataccaaag
    10261 tggtctataa tagttttttc tttggttatc ttaattacaa gtgcatctcc aattatggga
    10321 gcaaatgttg gaagtgctat ttctgaatgt gttgcatttt tactatttat actattgata
    10381 tataatgtaa agatagattt caaaaaaatc gtattattag gtatagcagt agtatttgta
    10441 ttaggagttt ttgtagcaat agatatgatt ttgggaagta attcacattt aggcatgttt
    10501 gtaaaagaaa tttactttaa tggaccagga gaaataatac aaacatttag tagaaagata
    10561 gagatgaatt taaagctagc tcaaaccagt gcatgggtaa atatactgtt aactggaata
    10621 ggtgtaattt tagttcttat gattaatcag attagatact ttaagcaact gatggatgag
    10681 tatccaattg tatttaaagg atttatagca tcaatagcag gatgtttagt aactctttta
    10741 gtgaatgact ctgggattgt gtcatcagct acagccttta tttatgtaat tgtacctatg
    10801 ataacattaa gtataaatct tacagcatta aaagaataag tactgtatga ataatatgta
    10861 aatatgaaca cattaattta acttctttat ttacaaaata aagaagaaag tttataaaaa
    10921 ataaattata ataaaaaaga gtttatctca aaattgatta ttctaatcaa attttaagat
    10981 aaactttttt tattataaag ataaataaca tataacctca tattttaggt agattttttt
    11041 cttatatgtt taggagtgca tttaaatttt tccttaaaaa ttctgtaaaa taattttgta
    11101 ttagtaaatc catgagcttc taatatactg cataaggtat catttgtgtt aattaaatct
    11161 ttataaatat gagaaatacg cacatcattt aaatactcta agtaagtttg tcccatatac
    11221 tgtttaaatt ttctacaaaa atattctggt tgtaagtgtg ctaccttagc gattttgtta
    11281 atagaaatag gcattttgta attaatcttt gtatattcta aaactggttc aaattttgac
    11341 aaatcaagta ctgttttttt catattttta ttacctacag atattttaaa gtttgtatat
    11401 aattcaaata aaagttcaaa taataagctt gtaaagagca gattagctgc aggaggagaa
    11461 ctaagtttaa tttctctcat gttttctaat ataagtttaa ctttacttga atttttttta
    11521 tagttattgt cattggcatt aaccttaaag tcaaaatagc aatttttaaa atcagggata
    11581 tatttgttta gaaaagacaa tggtacttgc aataatatag aggtattttg ataaatacat
    11641 ctagttgagt gaataattcc agaattaatg aacatacact cattagcttt taaattataa
    11701 gtgtaaccct ccatgttaat ttgtaaatca ccagaagtta tataaattat ttctaatgag
    11761 ttatgccaat gatttgctac ataactacca ctatcatcaa atagtttgaa attaacatct
    11821 aaattatcaa taggttcaat tatttcatgt gaaaaattat ttctgttcat aataatatcc
    11881 tccttataat tttaaattat aaatagtaaa tttataatgt tcaatattaa aaagataata
    11941 tagactaata aattagataa taaacatact taagaaaacg gataaaatca aatataataa
    12001 ctgtatatta aaataactta aaaaaattat tttattataa gtgcaaaata tacctattta
    12061 aataagataa gaggggagga ttttatgtgt atataaaagg tgtaaattta ggaggttggt
    12121 tagttttaga aaaatggatg acctcaagtt tatttgaagg cacagaagct gaagatgaat
    12181 actatttacc aagacagctt tcaagagagg catatgaatc taaaattaag actcatcgta
    12241 gtgaatacat cacagagaga gattttgcaa cgattaaatc tatgggattt aattcagttc
    12301 gtataccagt accatacttt atttttggag attgtgaacc attcatagga tgtgttaaag
    12361 aacttgataa agcatttgct tgggcagata agtatgggct tagtatattg atagacttac
    12421 atacagttcc aggaagccaa aatggatttg ataatggagg aatatcaggt atatgtagct
    12481 ggtcacaaaa tccagaatat gtagcgttta cattaaatgt attagaaaga cttgcaaaac
    12541 gttatgggat gaggcatgaa ttgtatggaa tccaaatttt aaatgagcct ataacagaaa
    12601 gaatgtggaa cataatgaat gttccaaatc ggtttaaggc tgtagataag gagatggcaa
    12661 gggggagtaa acctaattca ttagagtttt tacgtgattt ttatataaaa gcatataagg
    12721 taatgcgtcc ttatatgaga gaggaaaacg ttatagtatt tcatgatgca tttgaattaa
    12781 aagcatggaa agactttatg agagaggaag aatttaaaaa tgttgttcta gatacacacc
    12841 aatatttgat gttagctgaa gcagatggat gtgaacaaag tattgatagc tatctcaaat
    12901 atattaggga aaattatgct aaagatattt tacaaatgca aaaatatttt cctgttatat
    12961 gtggggagtg gagcttattt aattcatatg cttgtggtat agatacaaat ggaggtcaat
    13021 cacctctaaa tgggattgaa tcaaatatag ataaattatc aaaagacgat aaaagagaat
    13081 tatataggaa gatagcaaaa gcacagcttg atgcatggag aaatggaagt ggtcactact
    13141 attggaatta taagttatta ctagatacag ttaatgaaga aggttggata ggatgggata
    13201 gttgggacct aggcaaatgt gtagctcaag aatggtatcc tatagaatat taaactaaaa
    13261 ttggaggaaa agatatgatt aaaaacccta tacttccagg ttttaatcca gatccttgta
    13321 tttgtagaaa gggagatgat tattatcttg tagtttcatc ttttgaatgg tttccaggta
    13381 tacctgttta tcactctaaa gacttaaaaa attgggagtt atatactcat attttgacag
    13441 atgaaacaaa aatagatttg aagaagcttc cttcatctaa aggaatttgg gcaccttgtt
    13501 tgacttattg tgaagaagaa gatttatttt acatagttta tggaattatg aactctatga
    13561 atgcaagata ttttgatgtt gataattatt taattacatc aaaagatata aagggagagt
    13621 ggagtgaacc agtatatcta cactcatcag gttttgatgc gtctattttt catgatgatg
    13681 atggtaaaaa gtggattgca tcattagact gggagactag agaaggatat gaaaaacctg
    13741 gtgttatatg tttagtggaa tactgtacaa aaaagaaaga aatagtagga tatccaaaga
    13801 gaatatggtc agggggaact gatagaggtt gtattgaagc accacatata acaaagcgtg
    13861 gagattacta ttatataatg tgtgcagaag gtggaactgg atatggtcat agtgtaacta
    13921 tgggaagggc taaaaatata tggggacctt atgaaaaaga ttcaatgaat ccaattgtaa
    13981 cttcaattcc aggcgatttt tatgaaagac atgaccctga ccatctaaag cctaaatact
    14041 ataatccaga atcaaaactt caaaaatctg gtcatggaag ctatatagaa acaacatcag
    14101 gtgaagtata tttagttcat ctaacatcta gaccatttgt accagagtta aggtgtactt
    14161 taggtagaga aacagctatt caaaaaatga aatggacaaa ggataattgg cttcgaatgg
    14221 aagatgaaag taatttggca aaagaatacg tatcagaaag taaactagaa gaacatttag
    14281 tttcatctat accaagtttt gatgactttg attcaaatga attaggttta cagtactatg
    14341 ctcctaggat ttcaccatta tcatttgcag atgttaagtc tagaccagga tatgtaagga
    14401 ttagaggaca agaatcaaga acatcattaa ataaagtgag catattggca agaaaattaa
    14461 cttcagtata tgcaagaata accactaaga tggagtttta cccagaggta catcagcata
    14521 gtgcgggttt gataatgtat tatgataata tgaattatat aaatttaaga aagtattata
    14581 gtgaaacatt gggtcaaagt gcactatcaa taatacatct tgaaaatgga gagaaaacgg
    14641 aatttttaaa tactaggata ccaataaaag atataccaat atatcttcgt ctgtatgtac
    14701 aaggtcgtaa gtcatatttt gaatggagtt atgatgaaaa aaactaccag agaataggaa
    14761 aggtatttga tacaactaag ttttcagatg agtactgtaa atatggagaa tttacaggta
    14821 cgtttatagg attaacttgt gcagatcgtg taaagcataa acactatgct gattttgatt
    14881 tttttgaata tatagtagat gaatcaaaag atgtcgatta ataaaatcat tactaaaatt
    14941 ttcagagcaa aggtaaatct tatgctctga aataagaaac attagaaggc aaatcttaca
    15001 aaaaggagta tggtattatg aatacagaag ttaatgttaa agcaactacg attagatatg
    15061 aaaagatttc attttttgaa agaatttctt atggttgtgg ggatttgggg tgcaatatca
    15121 tatactcagc tatgtcagca tttttgctgt tttattatac taattatgca gatgttagtg
    15181 cagcagctgt aggtagtatt atgcttgtat ctaggatact ggatgggttt agtgacttaa
    15241 caatgggaat tatagtggat agaactaaat ccaaatacgg taaggctagg ccttggattt
    15301 tgagaatggc gattcctttt gctatagcag cagtattatt attttctgtt ccatcaaatc
    15361 ttggtatcac ttctaaatta atttatattt ttattacata taacttagtt tctactgtta
    15421 tttatacagc aatcaatgta ccctatgcaa ctctaaattc acttataact caaaaccagt
    15481 atgaaagagg agtattaagt atatttagaa tgatattagc cacttgtggt accttactaa
    15541 taaatggact tacactacct ctagttgaat actttggaaa taatttatca gcatggacta
    15601 aaacattctt tgtatttgga atagcatcta taatggtatt ttttataaca tttactggaa
    15661 ccaaggaaag agtaaaagca gttaagcaag ataggaatga agtaatacca tttaaaatag
    15721 gtattaaatc tttatttaga aataagtact ggatacaaat aacattatgt ttagtttgta
    15781 tatttattgt atttgcgata aatggtggtt catccgtata ttatgcaaag tttattttgg
    15841 gagatgaaaa attatttggt cctataaata tggtttcaaa tatatcccaa attatagcta
    15901 tgtttatggt tgctcctttt ataaaaaaat ttggaaaaag aaatgtatta atagtaggtt
    15961 caataatatt aatatcgtca aatgttatgt ttataatagt tggacaaaac tatataggag
    16021 taatatctgc aagtgctata aagggaatag gaagtgctgg aatagcatca acaatgtttg
    16081 ctattgtttc agatactatt gaatatggag aatggaagac tggatataga actgaggggc
    16141 ttataaatag tgcatctagt tttgggttta aagtgggaaa tggattaggt tcagcaatat
    16201 taggtgcagt attatcaatt ggtggttatg taggaacatc agctactcaa agtgatttag
    16261 ctatagtatc aataaaagta tgttttatat acctacctat atttataaca atattacaaa
    16321 ttatcataat gtctttttat aagcttgata aagaatatag tactatactt aatgaattaa
    16381 atactaaata atgaaaaagt ttcttataaa gtcttaagtt taattaaggt ctattgtaaa
    16441 tgttccttat aaaaactatt atatatttat gattattgaa gaatttttag agaagcgaat
    16501 aataaaaata taagaagact ttaaatgatg aaatggttgg ttttttagaa atgatttaat
    16561 aagttattgt tatttaaagc attataagtg gacaattaat ttttaattta tggagatgat
    16621 atttaacaat tagaagtaat atataatatg cactaagaag caatttttca actatttatg
    16681 aaggtggtgg tacaagaaaa gtatcacctt ttttttgtta tacaaaaaaa cagttgactt
    16741 tttatatgaa ccccttctat aatgttactg aaattaagta aaatgattga acaaatgtaa
    16801 agataattga aaagcttgat tttggaggaa agcaaatgaa aaaaattgga gacttaagat
    16861 taatgatgaa gtgttgttca ctttattacg aagataattt gaatcaacag gaaatagcaa
    16921 atcaattggg aatatcaaga ccaacaatat caagaatatt aaaagaagct tttgaacaag
    16981 gaatagtaaa aatacagata gttgatgttt tgaaaaatga ttaccaaaaa atagagagaa
    17041 gtttggagag aaaatataaa ttaaaagaag taatagtagt agatgataaa caggatgcac
    17101 taacacaaaa acaagaacta gcaagagctg tatctgaata tttaactaga gtagtaaagg
    17161 aaaatgatat aataggtgtt tcaataggaa caacactaaa agaaatacca agatatgtgg
    17221 aaaaaagtaa ctgtaaaaat gttacattta tacctctatt aggagggatt ggagacaatg
    17281 aaatagatat tcatgcaaat caaatagcag taagtttagc gagggctttt ggaggtgatt
    17341 ttaaattatt acatgctcca gctgttatgt ctgacttgtc tacaaaagag aaactttgca
    17401 aagacgaaaa aattaaagaa gtactagatt taatagataa aacaactata gcaattgtgg
    17461 gtataggaaa tcctatgagt ttaaactcaa caataatggc ttctggatac atgaatgaag
    17521 cagatataga agatttaaaa aaatacaact caataggtgc aatttgttta caagcctttg
    17581 ataaagaagg aaaaacttct atacttgaat ttaatcaaag agtattagga gtgaaactgg
    17641 aagatttaaa aaagataaaa agaacaatag gtgtcgcttc aggagatgaa aaaatagagg
    17701 caataaaggc atcattaaaa gcgaaattta taaatagttt agcaattaat cacagtttag
    17761 cacttaaatt attagaagat tgtgactaat agaaagatag ataaaagtta acaggaggga
    17821 atgtatatgt caatatcaaa agaaacattg cttgaaatgt ataagagaat gaatcaggct
    17881 agaaaatttg aagagaaagt tagttggttt tttgcaagag gtatggttca tggaacaact
    17941 cacttatctg taggtcaaga agcgtcaagt gtggcggctg taatggcttt agaaaaagga
    18001 gatttagtat cattaactca tagaggacat agtcaattta taggaatggg aatagaccta
    18061 aataaaatga tggctgaact tatgggtaaa gaaactggat tttgtaaggg aaaaggaggc
    18121 tcaatgcata tagcagatat tgagtcaggt aacttaggag caaatggagt tgtaggtgga
    18181 ggtcttacaa tagctccagg agctgcactt acacaacagt ataaaaaaac aggcaaaata
    18241 gttttatgta gttttggtga tggagcatca aatgaaggta cttttcatga aggaataaat
    18301 ttatcttcaa tatggaaatt gccaataata ttttactgtg agaataattt atacggtatg
    18361 tcaacaagca taaaacgtca tatgaatata gaaagtattg ccactagagc agcttcttat
    18421 ggaatagaag gaatatcaat agatggatat aacccaatag aagtatacga aacagtacaa
    18481 aaagctgctg agaagtgtag aagaggagaa ggacctgtat taattgaaag tagaacttat
    18541 agatggttag gtcattcaaa atcagatgca aatgtatata gaacaaaaga agaaatagaa
    18601 tcatggaaag caaaagaccc tattgaattt ttaaaaaatt atcttataga aaataatcta
    18661 tctaatgaag atgaattaga taagattcaa gaatttgcaa agcaatcaat agaagatgca
    18721 gtagagtttg ctcaaaatag cccaaatcca aaaatagagt ctttattaga ggatgtatat
    18781 gcagactaag aatggtaaag gaggaaaata aaaatgagta caagggaatt aacatatgca
    18841 caagcaataa aggaagcaat gtcagaagaa atgagaagag atgaaaatgt aatatttatg
    18901 ggagaagata taggaatata tggaggagca tttggtgtat cagttggtat gatagatgaa
    18961 tttggaccag aaagagtaag ggatactcct atatcagaag cagctatagc aggagcggca
    19021 gcaggtgcag cagcaactgg cttaagacct attatggaag taatgtttat ggactttgta
    19081 acaatttcta tggatgcaat tgtaaatcaa gcggcaaaaa tgagatatat gtttggagga
    19141 aaagcacaag ttccaatggt tgttagatgc ccaggaggtt ctggaactgg ttcagcagag
    19201 caacattcac aaagtttaga agcttggttt tgtcatgtac caggagtaaa agtagttgca
    19261 ccttctacac cagcagatgc taagggattg ttgaaagcag ctataagaga taataatcca
    19321 gtcatatttg ttgagaataa attgttatac agaaaaaaag gttttgtgcc agaagatgat
    19381 tatgtaattg aaattggaaa ggcagatatt aaaagagagg gtactgatgt tacagtaatt
    19441 acttatggaa gaatgttaca aagtgttgaa gaagcagcag agactctatc aaaagaaaat
    19501 ataaatgttg aaattataga tttaagaact ttatatccat tagataaaga gactatagta
    19561 aagagtgtat gtaaaactgg gagagtttta atttgccatg aagcagctaa gactggtggg
    19621 ctaggtggag aaatatcagc cctgataaca gaaagtgaat catttgatta tttagatgct
    19681 ccagtaaaaa gaatttgtgg aaaagatgtg ccaataccat ataatccaga gttagaaaaa
    19741 gcagttgtcc caagagttga tgaaatagaa gaagcaataa aatctttaat tgttagataa
    19801 ggagggatag atatggtggc aaataaaata aaagccacac cagcagctag aagtcaggca
    19861 agaaaagaca atataaaatt agataggctg attggaagtg gagaaaatgg aaggattcat
    19921 ttagtagatg tgttaaatta tttaaaagat aataaagcaa atactactcc tttagctaga
    19981 agaatagcag aagatttaaa tatagattta gaaactattg taggtactgg atataatgga
    20041 aagataagaa agtgtgatgt ggaaaaatta actgcaaaag aaactattgt atcaactaat
    20101 acatctaaat ctagtgagaa aaaagagctg aaaattgaaa atgaaaattc aagcatgttt
    20161 aacacagtag aaggaatatt tgaaaagcca aatccaatga gagccactgt agcaaaacga
    20221 atgtcagaaa gttattttag tgctcctgta tttacattca atatagaagt agatgctaca
    20281 gaattgaagg tacttagagc aaagttaatc gacacagtaa aagaatcaac tggagtaaaa
    20341 ttaactatga cagatttaat agtaatggca gtatctaaaa tacttccaaa tcatcaagcc
    20401 ttaaattcag catggacaga tgagggtata tttagatata aagatgtaaa tatagctatt
    20461 gcagttggtt tagatgaagg cttatatgtt ccggtagtaa aaaatgcaaa caaaaagtct
    20521 ttaaaagaaa tagcaaaaga aagcaaagaa cttgcggaaa aagtaaagac agggaaactt
    20581 atgccagcag accaagaagg taatacattt acaataagta atgttggaat gtatggtata
    20641 actacattta cacctataat aaatatgcct tcaagtgcaa tcttaggggt aggtgctaca
    20701 caagataagt ttgttccagt aaatggagag gctaaaataa aacctataat gaacttatca
    20761 ttaacatcag accatagagt aatagatgga acagtagctg caaaattctt aaaagattta
    20821 aaagaattgt tagaaaatcc tttatcaatg cttgtatagg ttttgatatt ttgttactga
    20881 tataaatagt ttgaatagat tatattatta taattgtttc agtaaattta aagcttttat
    20941 atattaagaa ttatttttaa cagtaactat atgtgaatat gatttgctta attaaaatat
    21001 aagaaaataa ataggaggag agcctatgtc agtagaagta ataatgccaa aagcaggagt
    21061 agccatggaa gaaggtacta tagtatcttg gctaaagcaa gaaggcgaag aagtaaagat
    21121 tggagaacct atactagaaa taacaacaga taaagttaat atggagatag agtcagaagg
    21181 agaaggtaca cttgctgtaa tcatacataa agaggaaggt gaagtattac cagtatttac
    21241 agtaataggt gtaatagcag aaaaagggga aaatcaagag gaagtaaaag ctaaatattt
    21301 atctggaaat gtttcaaaag aagatacagt taaagagaat caaaatatag aagttaaaga
    21361 agaaaaaata aacaaaaaag agtgtaatca tgattatgat gtagtggtaa taggaggagg
    21421 acctggggga tatttatcag cattaaaagc agctctttta ggtggaagag ttgctttagt
    21481 tgaagaaaat atactaggag gtacttgctt aaatagaggt tgtatcccta caaagactta
    21541 tataaaaaca gcagaaatat tagaagaaat tgaccaatta tcaaagagag gtgtaaaagt
    21601 aactgtagat aaagaacagg acattaagaa ggccataaaa tataaaaata gagtagttaa
    21661 aaaacttaca gctggtgttg gcggattatt aaaaagtaga gatgtagatg tgtttaatct
    21721 taaagctagt gttaaagaag agcataaagt aattttatca gatggaaaag ttttagatac
    21781 agaaaatata ataattgcta caggttccaa agtaaggata ttacctataa aaggaataga
    21841 atcaaattta ataataacta gtacagaagc attagatttg gaaacagtgc cagaagaatt
    21901 agtaataatt ggtggtggag tgattggttg tgaatttgca gagatattca attcaagagg
    21961 ttctaaagta actatagtag aaatggaaga tagagtaatc ccaagaatgg ataaagagtt
    22021 aagcgaatct ttaaaatatt ctctcagtaa aaaaggtata aatgtattaa ctaaaaagaa
    22081 agtttctgaa tttaaagaag aaggaaataa catattagtg tgcattgaag gtgaagagcc
    22141 aataaaagca gatttatgtc tatatgctat aggaagagaa gctaatcttt ctggcataga
    22201 ggaattagat attaaaatag ataaaggttc aatagttgta aatagtaaaa tggaaacaag
    22261 tataccaagc atatatgcag taggtgatgt tactggaggt gtaatgttag ctcatgctgc
    22321 ttttaaaatg ggagaggtag cagcttcaaa tgctctaggt gtgaataaag aagttgactt
    22381 aggtgcatta cctagttgtg tttatacaat tccagaagta gcatcagttg gtattacaga
    22441 agaggatgct agaaaaaaat ataatgtaaa agttggtaag tttaattttg ctggaaatgg
    22501 aagagcttta gcttctggtc aagaacaagg atatgtgaag gtagtagcag atgctaaata
    22561 tggagaaatt ttaggtatac atatgtttgg atgtggtgta gcagaactta taaatcatgc
    22621 agcatcattt aaagcgttag agatacctat tgatgaagca agtgagttga tatttggtca
    22681 tccatgtact tcagaagctt taatggaagc tttggcagat gtaaatggag aatgtttaca
    22741 cttacctaaa aaataaatct aaacataaat tattaattta agtctattat taatattaat
    22801 ttatatcata aaattttaaa acacttactt agccataccc cttattatgc aaataattta
    22861 tttgcataat aaggggtatt ttttatggaa aaatatagaa tatagaatcc ttgtagtttt
    22921 tgttgtacaa aaaagatagt aatataaaat aacattatca ttttagaatg atttcaattg
    22981 taattaggaa aagtgatttt tttgttttta aaaaaagtat tatttgtaaa atataaaaaa
    23041 aaatttctta atatttgaat aaaagaatag cttaatttaa atgttattac tttataaaaa
    23101 aataataagt acaaaaaaaa caatatatgg catataagtt gctatataaa taataaggag
    23161 ggaacaatta taaatgaggc aaagaataaa aaacttaatt gaaaatgaag ataagaaaaa
    23221 tcctttaaca gatgaagcga tttcaagtag gttaaatatt cgaagagaag atgttacctt
    23281 tttgagaaat gagttaaaaa tagaagattc aagacaaaga agaaaagttg ttttaattaa
    23341 agctataaaa gatattttaa aagaagaaaa aactataaat aaaaatgata taacaagaag
    23401 attaaacagc attgggttta cagtatcaag atttacagtc atacaatact taaaagagat
    23461 tcaagattct ggtgacctaa aacttgataa agagagtgat gataaaaaag aagaaataat
    23521 caataataga gaaaataaag atatagcatt tgataaactc ataggtagta gtggtagctt
    23581 aagtacaatt ataaaactag ccaaagcagc aattctttat ccacctaatg gtcttcatac
    23641 tattattatg gggccaactg gtgttggaaa gagtgagtta gcagagtgta tgtataaatt
    23701 tgcagtagaa tcatccagat tccctaagaa tgcaccattt atagttttta atgcagcaga
    23761 ttattcagag aatccacagc ttttgctatc acagttattt ggacacgtta aaggtgcttt
    23821 tacaggagct gatgagaaca aagaaggatt agtatcaaag gcagatggag gaatattgtt
    23881 tatagatgaa atacatagat tacctcatga aggtcaagaa atactatttc aactgattga
    23941 taaaggtatg gtcagaaagt taggagaaac aagactaaca cataaaatag atgtaatgat
    24001 tatttcagca acttctgagc caatagattc tcatttactt aatacattta aaagacgtat
    24061 acctgtaaca attgaaatac cagaattagt tgcaagacca ttaaatgaga ggtttgacat
    24121 tataaataat ttcttcttaa tagaagctca aagaatggga gcaaacatac atataaagtc
    24181 agatgtatta aaagctctta tgctttacga ttgtataggt aatgtaggtc aacttagaag
    24241 tgatattcaa gtagcttgtg ctaggggact attaaaccaa cttacaaaca aactaaaaga
    24301 agtaaatata agcatatcag atgtacctgg atatgtaaaa caaggtctta taaaaatcag
    24361 aaattgtaga ggaaaaatag aaaattatgt agatggggat ttaattatag actcaaatct
    24421 tcaaggtgag atagaaaaga aaaatgaaga tatatatact tttccagatg aaatatacaa
    24481 acttactgaa agaagacata ttgatttatt ggaacaaggt ttagattttg atgttataaa
    24541 tagaatcatt ggaggagaat tagaaagttg cattcaaaaa tacataaaac aagttaaaaa
    24601 agtttctatt agtaacaatc ttccagatat aagtccaatt gttggaaaat atatcgtaga
    24661 gctaacttat gaagtaatca aaatagcatc acaataccta agttcactag aaccgaatct
    24721 acatttatgt ttagcagttc acctaaaagc agcttttgag agattaaaag aaggaaaagt
    24781 aatatcaaat gctcatttga aagaaataat aggaaattat ccactagaat attctgtagc
    24841 agaaaaggta gctcaatatt taaaggaaag atataacata aacttaccaa aagaagaaat
    24901 aggtataata gcaatatatt ttaaaatgag tagtagaaga gatatgtctg aacaaaaaaa
    24961 gataggtgta cttcttatgg ctcacggaag agtagcatct tctgtatgtg aggttacaaa
    25021 taaactatta ggaattaatc acgcaaggta tttagatatg ccatttgaga agaaaccgga
    25081 agaaatgatt gaagaagcta ctacaataat aaaagatatt gatgaaggta gaggtgtgat
    25141 tatattagta gatatgggtt cactttcata ttttggagat attatttctg gaaagactgg
    25201 aattaatata aggacaatat ctagatttga tacattgctt tctatagagg ttatacgaag
    25261 agcagtttta ccagatttaa caatagacga gatagttgat gaagttaaag gtatagagcc
    25321 acaagtaaaa gaaaaggtta gtaaatgtaa taatacaaaa gtagatttta gaaaacctat
    25381 aattttaaca ttatgtatta ctggattagg gggagcttgt aagataaaaa aaatcctaga
    25441 ggaaaatatt aaaagtataa ctgaaaaggt tgatatagaa cctataggta tgattgaata
    25501 tccaagtctt gatttagaga taaaacaaat aagcaatgat aaaaatgtaa tcgccatagt
    25561 tggaacaatt gaccctcaga tagcaaatat cccttttttt agtctagtag acataaatga
    25621 taaagcaaag ttaaatcaaa taaataacct aattgataca aatcaaattg gtgaaacaaa
    25681 taaaaaatat gaattatcag atttaataca taaagaagat atatttgtgg acttacaggt
    25741 taaatcaaaa gaagaagttc taaaatatat gagtaaaaaa cttagagaga aaggttatgt
    25801 gacaaaaaat ttctataaaa aagtagtgga aagagataac ttatttccaa ctgaattatc
    25861 agatgaaata gcaatacctc acacagatgg aatagatgta attaggccag ctataagtat
    25921 agccatctta aagaagccta ttgtgtggag taaaagtaaa gtaaaaataa tacttttatt
    25981 agctgtagac caaaagtgtt ttaatccatt aagcactcta ctctcattta tagaaacaga
    26041 tgaatttaag aagataaaaa acattaaaga tagagatttt attagggaga tgatattaga
    26101 tggagtcaat gaaaataatt agtagcaatt taatttttaa aaatattgaa gtgtctaaca
    26161 atgaagatgc attaaagttt ttgggacaac gtttgtttga cgaacagtat gtaaaagaaa
    26221 gctacataca agctgttgta gcaagagaaa aaaagtatgc tacagggtta ccaacagaaa
    26281 tatacggagt ggcaatacca catacagata tagtacatgt aaatgagcca ggaatagcaa
    26341 ttggaatact gaataaacct gtaaaattta taatgatggg tacagacgat actgaaattg
    26401 atgtaaaagt tgtatttatg ttagcagtga aagagccaca agaacaattg caactattag
    26461 aaaaacttat gactatattt caagataaga atatactaaa taatattgtt gacttaagtg
    26521 aagaaagtgt gagtgattta ttaaactcta aattgaaaaa ttaaacatgt aaagtatatt
    26581 aaaaatgtaa aaagattatt aaagatttct aactatagat atctttaaaa taaaataatt
    26641 tcaatggggg tgactaatgt ggctaaaaag atattagttg catgtggaac aggagtatgt
    26701 acttcaacaa ttgctataaa caaattaaag aaagcacttc aagacattgg taaattggat
    26761 atggttaata ttacacaatg taaagtagta gaagttgcat caaaagcacc tgattatgat
    26821 ttaataattt gtactacaca agtatctagt agtataaaaa caccagtgat aaatggatta
    26881 ccttttttaa ctggtgtcgg aatggataaa ttaatcaatg atgtattaga agagttagaa
    26941 ttataattaa aaaaattaag gaacatggtc tctaaaatta taagttttag agacttaaaa
    27001 ttaaataatg gagggtcttt atatggagat attaaatttc attgttggtc taggtgcaca
    27061 agtaatgatg ccaataataa tatgtatttt tggtttgata ttaggtacaa aactaggaaa
    27121 atctttaaga gctggtttaa ctgtgggagt tgggtttata ggtcttaaca ctattatagc
    27181 tttgctaaca gataatttag gtccagctac acaacaaatg gttaagaatt tagggctaag
    27241 tttatcaata atagatgtag gatggccagc agcatcagct atagcttttg catcaacagt
    27301 aggggcttta attattccaa taggtcttgt ggtaaatata gttatgctaa ttactaatac
    27361 tactcaaact gttgatgtag acatatggga ttactggcat tttgctttta caggagcttt
    27421 agtggcaggg gctactcaaa gtgtaatgtg gggagtattt gcagcagtag caaatatggt
    27481 aattgtattg gtaatggcag atttaactgc tccaggtata gaggaatatt taggtatgcc
    27541 aggtatatct cttcctcatg gatttacaca ggcatttgtt ccaattgcta tagtagtaaa
    27601 taaattatta gacctaatac caggtataaa taagattgag ataaatgctg atacattgca
    27661 gaaaaaattt ggattatttg gagaaccttt aataatgggg tctgtaatag gtgtaataat
    27721 tggtattgct gcgaaatatg atataaaagg aatattacaa ttaggtgtaa ctatgggagc
    27781 tgtattaata ttaattccaa agatggcagc attattaatg gaaggattat taccagtatc
    27841 agaagctgca caggaattta ttgagaagag atttaaaaac agaggaaaga tttatatagg
    27901 cttagattca gcagtaggaa taggtcatcc tgttacatta tcagttgcac tagtgttggt
    27961 tcctttgact atacttatag cagctatatt gccaggaaat aaagttttac catttgcaga
    28021 tttagcagta attccatttg cacttgtatt aatcgtacca attacaaagg gaaatgtgtt
    28081 tagaacatta ataataggaa taattataat tacttctgga ttattaatcg caactaactt
    28141 agctccatta tttacccaaa tggctttaaa tgctagtttt aaaatgcctg aaggagcaac
    28201 tatgatttca agtatttgtg atggtgcgaa tccattaagt tgggtatttg taaaagttat
    28261 gaactataaa gttattggag gagtaatttt tggagttata gctttaggaa tggctattta
    28321 caataggaat agaataataa atgaaaataa aaagctatct atagaagaat aaggttaaaa
    28381 caattttatt aaggagtgta taggttatga aaaaatataa atatgattct aaaaggtact
    28441 tactcagtgt tacaatacca ggatttttta tgattttaat attgatttat gcactgttta
    28501 ataactatac aaattttaat ttgaatatat atagtttgtt aataattgtc tgtacttatg
    28561 gtatattcaa tacttttata tcatcaagta atcctaaaaa aattattatt gatagcaaat
    28621 gtatacattt tacctcattt atgactacac ataagtatga aattaaagat atagaaaaga
    28681 taagaataag agaattttat aataaaaaaa tttatctaaa aattaatgat ggaaaccttt
    28741 ttaaaggtag gtattggata agaacaaata tgtttaataa tagtatagca ttatatagct
    28801 atttcattga gttggaagag tgcttatatc cagattcact aaaatttaga aataaaaaat
    28861 ttgagaataa gaatatataa aaataaaaaa ttgaattgaa gcctagctta atcttttttg
    28921 ataagatata agtttgaact ttatactaaa tttttagaat tttcaatcaa gacaataaca
    28981 taatagctaa gcaattagaa cacaattaag atgtataagg catgtatatg atgaatggga
    29041 ggatttaatt aatgttatta gagaaattaa gaaaagaagt attacaagca tctttagacc
    29101 ttttaaacta taatttagtg acattaacag gaggaaatgt aagtgggaga gatgaacaaa
    29161 ctggctatat agcaatcacc ccaagtggaa tggattatag aaatcttaca ccaagtgata
    29221 ttgttatagt agatgtagat ggaaatatta tagatggaaa atggaaagca tcagtggatt
    29281 tatcagacca cttgtatata tataagcata gagaagacat aaatagtata attcatacac
    29341 attctacata ctcaagttgt tttgctattt taaatgaacc tatagaatgt gcaagtacaa
    29401 ctcttgcaaa tgaagtaggg ggttcagtac cagttgcaaa attttcacca ccaacatcta
    29461 aaaagatggg aaaatgtgtt attgaagcaa ttggtgacaa aagagcatgt cttttagcaa
    29521 atcatggcgt aattgcagtt ggtccatctg taggacatgc tcttacagcc gctgtaatgt
    29581 tagaagattc agcaaaagta tattacttag caaaatcaat tggcacacca gtgctactgc
    29641 ctgatgaaga aattcaaaga gcgagagatg tattttttaa tgtctatggt caggataaat
    29701 aaattagata aaattttaaa agtaatatga aaatatagat attcaatgat attaaggaga
    29761 tttataatga tataataagt ttaatagtta agaagtaaaa tatgaaatgt aatagtatat
    29821 aaattcattt aagactaaaa ataataagat aaaataaaaa ggagtctgta tttctatgta
    29881 ttacttatta aacaaaagca caaatcctta ctttaatttg gcattagaag aatatctatt
    29941 tttaaatgat aaatataatg atgatattat aatcatatgg agaaatgaag aatccatttt
    30001 tataggtaaa aatcaaaatc catatcagga agtatatcat gatgttattg aaaagggaga
    30061 aattcctatt ttaagaagaa tatctggagg aggaactgtt tatcatgact taggtaatat
    30121 caatatgtca ttcatacaaa aagataggca acttcatgag atagattttt tggagcatac
    30181 taagtttatg caaaagatgc tttcaacctt aggactagat gtatctataa ctgaaagaaa
    30241 agatttattt ttaaatggga aaaaaatttc aggttctgca cagtctataa aaagaaaaaa
    30301 ttctctttat catggaactc ttctttacga ttcagattta aataaattaa ctaaatattt
    30361 aaattcaaat aaagcaactg aatcaaatgc aactaaatct gtttcaagta aagttacaaa
    30421 tattaagttt ttactcgaaa aagatataaa ttacttttta gattattgtg ttgaatattt
    30481 aaaatctaat ataaagaata taaaagaact tgaattggat gaagaagata ttaaaagtgt
    30541 atacaatata ggagaagata aatataaaaa gatagagtgg acatatggta aaacgccgaa
    30601 atttcaagta gtgctaccat ttaataatga aagtaaaata aatatacatg ttaacagatg
    30661 gaaagtatca aaatttttta tttcttatga tgataatgta attaatatgg acaagttgtt
    30721 agatttgaat ttctttaaag aagaaataaa agagagtatt ttagaaaatt atccacatta
    30781 catagattta atcaatttaa tattttaata taaaacctct aatttgataa aattgtctta
    30841 tatcaaacta gaggttttta atattcttgc atattaacaa ccattacaaa attgtaaaat
    30901 taaaaacaac actattgaaa aatcaatata tattgtaata aatatatgtg tttttcatta
    30961 gcaaatagac attaactatt tatacaactg aaaatttaat atataattaa tcagatggtt
    31021 aaaataaaaa tattaaaagt tttaataaat gatggttaaa aataaaatac gaggtgatac
    31081 catgtatagt gttataattg ttgcagcggg aagcggaagg agaatgaact tagatataaa
    31141 caaacagttc ataaaattaa gagaaaaaga aattattgct catacaattc aagtttttta
    31201 tgaaaatata aatatagatg aaatagtggt atgtataaaa aaagaagaag aagatttttt
    31261 taaagaaaat ataataaata agtataactt taaaaatata aaaatagcat atggcggaaa
    31321 agaaagacag gactcaatat ataatggttt aaaaaaatta gatgaaaatt gtgatatagt
    31381 acttatccat gatggagcaa gaccatttgt cgaccataga ataatcaatg aatctataaa
    31441 ggtagctaaa gaaaaaaagg ctgtggttgt aggtgttcca gtaagtgata ctataaagat
    31501 agtgtcagat ggaacagtac aagaaactcc agaaagaaat ttgctgtggg cagcacaaac
    31561 ccctcaaacc tttgaatata atctcataat agatgcttat gaacaagcat ataagaacaa
    31621 ttattatggt actgatgatt caatgttggt agaaaatata ggtcaaagtg tcactatggt
    31681 aatgggttct tatgaaaaca taaaaataac tagtccagaa gatttaaata tagcagaaca
    31741 aatattaaat atggaaaaaa gagatgaagt taacagtaga aggagaatta tatgagaata
    31801 ggattaggat atgatgtaca caaattaaca gaggatagaa aacttataat cggtggtgta
    31861 gagataccac acgataaagg tttgttgggt cattctgatg ctgatgtatt gatacatgca
    31921 ataatggatt ctattttagg tgctctagca ttaggagata tagggaagca tttcccagat
    31981 acagatgaag aatataaggg agcagatagt atgaaattat tagaacatgt gtataatcta
    32041 ataacaagta aaggatataa aattggtaat atagacagta ctataattgc tcaaagccct
    32101 aagatggctc catatattga gagtatgaga agtaatatat caaaagtttt aaacacagac
    32161 attgataata taaacataaa ggcaacaaca gaagaaggtc ttggttttac aggagcaaaa
    32221 cagggaatag cttcacaaag tatttgttta ttattgttga caagtcagaa taattaatat
    32281 attattagta ataagtttaa tggatatcaa gtaataggcc tatatagaat atctataatg
    32341 tatgaattta agtgaaatta atataaatat aaaattagct atgataaaga aatagtaaaa
    32401 tgatgaaatc ttcacagaga gaaaacggtg gtgagagttt tcaagaggaa gtctttgaac
    32461 ctgtctttta gcttaaaggt ataaaaatct ttacggtagg aaccgttata ttcccaaaag
    32521 agagctattc atatagctaa ctagagtggt accgcggaaa ttaaaccttt cgtctctata
    32581 cttgtataga gatgagaggt tttttatatt ttcagaaagt taatattcag gaggaatcta
    32641 ttaatgaaaa tgtcaaaaat gtttatgccg acattaaaag aaatcccagc agatgctgag
    32701 attacaagcc atcaattaat ggttaggtca ggcatgataa aaaaaatgac ttcaggtgtt
    32761 tataaccaat taccaatggg gttaagagtg ttcaaaaaaa ttgaacaaat aattagagaa
    32821 gaattaaata aaaaagattg tcaagaaata ctttgtgccg ccttacttcc ttctgaatta
    32881 tggaaagagt ctggaaggtg gactgctatg ggtgaagaaa tgtttagact aaaagacaga
    32941 acagaaagag agtactgtct tgggccaaca catgaagaag cattcactga tataataaga
    33001 caagaaatta cttcatataa acaattgcca ctgaacttgt accaaataca agtaaaatat
    33061 agagacgaga gaagaccaag atttggtgtt atgagaacta agacttttac aatgaaggat
    33121 gcctatagtt ttgatgtaga tgataaaggt ttagataagt catatcaaga tatgtttgat
    33181 gcatatgtaa gtatatttga tagatgtgga ttggagaata gccctgtaca ggcagattca
    33241 ggagctatag gaggttctac atcagccgaa tttatggtta agtcagaagt tggtgaagat
    33301 gaagttgtat tttgtagtgg atgtgattat gcagccaatg tagaaagagc agaatcttgt
    33361 aatctagtat cacaaaaaga agaaatgaaa gaattagaag aggttcatac accaggagca
    33421 gctacaataa aagagttaga agaattttta aaaacttctc cagataagtt tgctaaaact
    33481 ttagtatatg aggcagatgg aaaaacagtt gtagtcgttg taagaggaga tagagaagtt
    33541 aatgaaatca aagtatctaa tgctataggt tctgttatag agtttgctct tgctacagat
    33601 gatgtagtga gaaaagtaac taatgcagaa gtaggatttg caggtccaat aggtataaat
    33661 gctgactatg tatttataga taaagaaatt gttgaacaaa gaaacatagt tgttggggct
    33721 aataaaactg agtaccatat aaaaaatgct aactatggaa gagattttga aggaatagtt
    33781 ggagacttta gaaatgttca agaaggcgac aagtgtatag tatgtggtaa gccacttgaa
    33841 atagctagag gtgttgaagt aggacatata tttaaactag gaactaagta ctcagaatct
    33901 atgaatgcaa acttcataga caaagatgga aaatcaaagc ctatagtaat gggatgttat
    33961 ggaataggtg ttgaaagaac agcagcagct ataattgaac aacataatga tgagaaaggt
    34021 ataatatggc ctttgtcagt agctccatac catgttgtga tagttccagc aaatatgaaa
    34081 aatgaagaac aaatatcaat agctgaaaat atatataatg atttgcaagc tatgggtgta
    34141 gaagttttat tagatgacag agatgaaaga ataggtgtca aattcaatga ttcagaatta
    34201 ataggaatac ctatgaggat tacagtaggt aaaaatatta atgaaggtaa agtagaattt
    34261 aaacttagac ataaagaaga taaagagata attgacatag aagaaataaa tgaaaaagta
    34321 aaggcagagt ttatcaggaa taatgttagg ttaggataat aacttaaata agatattgta
    34381 tagataatca aagttgtact ttatagacac cattttatct atatataagg atataaaatg
    34441 gtgttttttt ataaaacaaa taaatgagga ggtaattgaa atggcaaaaa atgaaaaaca
    34501 atttgttgaa gaaataacaa agatggaaga tgattttcca caatggtaca cagatgtaat
    34561 aactaagact gacttagttg attatgcacc agtaaaaggt tttatggttg taaagccata
    34621 tggatatgca ttatgggaaa agatgcaaga atttatggat aaaaaattta aagaaactgg
    34681 acataaaaac tgttattttc cattattaat accagagagt ttattaaaca aagaagcaga
    34741 acacgttgaa ggttttgctc cagaagttgc atgggtaaca catggaggaa ataaaaaatt
    34801 agaagaaaga ttatgtgtaa gacctacttc agagactata atatgtacaa tgtatgcgaa
    34861 atggttaaaa tcatatagag aattaccata tctttataat caatggtgct cagttgttag
    34921 atgggaaaaa tcaactagac ctttcttaag aacatctgag tttttatggc aagaaggtca
    34981 tacattacat gaaacagcag aagaagcaca agaagaaaca atacaacaat tagaagtata
    35041 taaagcgcta tgtgaagaat tacttgcaat gccagttgta gctggtcaaa aaagtgaaag
    35101 tgagaaattt gcaggtggtg aaagaacata tactatagaa gctatgatgc atgatggtaa
    35161 agcattacaa tcaggtacaa gtcacttcct aggtcaacac tttactaagg cttttgatat
    35221 tacttttgca gatagagaag gaaatttagc taatccatac catacatctt ggggagcatc
    35281 tacaagactt ataggtggac ttataatgac tcatagtgat aacagaggtt tagtattacc
    35341 accaagagta gctccaattc aagttgttat agttcctata gctgctaaaa aaggaaatgt
    35401 aatggagact gttgataaaa tatatgctga tttaaaagct aagggagtag ctgtagaagt
    35461 tgatgataga gataactata caactggatg gaaatttaat gagtgggaaa tgaaaggtgt
    35521 tccagtaaga gttgaaattg gaccaaaaga tatagaaaat aatcaagcta tggtatttag
    35581 aagagatact ttagaaaagg attctatgcc tttagaagga ttagctgatg ctatatgtga
    35641 tttatttgat gttatacaca atgatatgtt tgaaaaagca agaaaacata gagaagacaa
    35701 tacatctata gttgaaaata tggatgagtt tagaaaagct ttagaagaaa agccaggatt
    35761 cataaagact atgtggtgtg gagatgcaga atgtgaagct aagattaagg aagaaacagg
    35821 agcaactata agatgcttac cttttgaaca agaaaactta ggtcacaagt gtgtgtactg
    35881 tggaaaagaa gcagatagta tggtagtaat ggcaaaagct tactaaaata catttaaata
    35941 aaaactgggg tagaaagtat ttaatacttt atcccagttt ttttgttttt tatgagtaat
    36001 aaaatgtatt tgtaactatg tcataagata agtcatagat acttatatta aaaagaatat
    36061 aatagagaac tatttttaat aattacatat taatgaaagc aaaatatttt tgttatatag
    36121 attttcaata aagcaaacaa taaatataaa tgaatattag taaggagtgc ttttaatttt
    36181 tagaaaataa atgacttaaa agaaagattt atgaaattaa aactaggatt ttctgatata
    36241 ataaacatgt gtatttttaa ataaaaagga tattattatt agatttgatt aaaaataaac
    36301 ttgcaaaaca atgtactagt ttaatattat agttatattg aataaaatat caggaggaag
    36361 taaaaatgaa tgtaagagta aggtttgcac caagtccaac aggatttgta catataggta
    36421 gtttgagaac tgctttatat aactatttat ttgcaaaaaa aatgggcgga gaatatatat
    36481 taagagtgga agatacagac caaagtagat tagtagaagg tgctatagag aatatgctta
    36541 atgctatgaa atgggctggt gtcaaccata gtgaaggtgt tatattagat gatagtggaa
    36601 aagtagtaca aaaaggagaa tatggtccat atattcaatc tcaaagatta gatatatacc
    36661 aagaatatat aaagcaactt ttagatagtg gaaaagctta ttactgtttc tgtacaaaag
    36721 aaagactgga tgaagtaaga gatgctcaaa gagcagcagg agaaacagct aaatatgatg
    36781 gtcattgtaa gaatctttct aaagaagaag tagaagcgaa tataaaagca ggaataccat
    36841 atgttataag attaagattg ccagagaatc atacaattaa gtttacagac ttagttagag
    36901 gagatatgga atttaatact aatgacttag atgaccaagt attaatgaaa acagatggat
    36961 ttccaactta tcattttgca gtagttgttg atgactattt gatgaaaatt acacatgtta
    37021 taagaggaga agaatgggta tcatctactc caaaacatgt ttatttatat gaagcttttg
    37081 gatgggaagc acctgtattt gtgcatttac caaatatact taataaagaa aagaaaaaat
    37141 taagtaaaag acaaggtgat gtagctgttg aagactttaa gaaaaaagga tatttaccag
    37201 agggattagt aaactatgta gcattagttg gttggtctcc tgaagataat caagaattgt
    37261 ttacaatgga ggaattagaa aaagccttct ctgtagaaag agtatctaaa agtggtggag
    37321 tatttgatac tgaaaaatta aattgggtta atcagcacta tataaaagat ggtgatgatg
    37381 cttatctaac agacttagca ataccatttt taatagaaga tggatttata acagaagaag
    37441 aagctactaa taaatatgat ttcttaaaga gtatgatatc agtacttaaa gagaaattac
    37501 aatatgtaaa agaagttact gaacatgcaa gtatattttt tggagataaa atagaggtag
    37561 aaactgaaga gggaagagag ttcttaagat tagaacatat acctacttta atagatgctt
    37621 tgagagaaaa aatagaaaaa acagaggtat taaatgctga gtttgttcaa gctatgctta
    37681 aagaaataca aaaagagtac aaaataaaag ggaaaaattt atttatgggc tcaagaataa
    37741 ttttgacagg gcaaatgcat ggtccagatt taccaaaagt aatggaagtt ttaggaaaag
    37801 aaacttgctt aaatagaata gcttatgtaa aaaataatat attatagtca taaaagtccg
    37861 ctaatttaga agcggacttt ttttgtgtta gtatttggtg aaaatatctg cttaagaaaa
    37921 tgaaggtatt taaggtaata aatttaatat ataaaaagca aagcaaaaat ataaataaaa
    37981 tatgaataat aaactaataa aatattaagc atagaagaag ggaatctatt attttagttt
    38041 gatttaatta ttaagggggt aattactatg tatagtaata ttgatgatgt taaaaaggaa
    38101 ttaaaggagc tatgcttaga atatgttaca attttagaaa aattaaaaga tgaaaaaatg
    38161 attacagaag aaacttttga aaagtgctct tctcaaaaaa aaatattttt agaagaacaa
    38221 tagaggatgg taatagtatt attattatgt agtttgaaag atagtacgaa aaatgatagt
    38281 aatactatta tttattgcaa ttttcaacta taatataata tataatgtta agaagataat
    38341 ttataaaaat acagtgaggt gatgagtgtg aaagtttata atacattgac tagaacaaaa
    38401 gaagaatttg ttccattaga agaaggaaag gtaaaaatgt atgtgtgtgg tccaacagtt
    38461 tataactata tacacatagg taatgcaaga ccatttataa tatttgatac tctaagaagg
    38521 tatttagagt atagaggata tgatgtaact tatgtacaaa actttacaga tgttgatgat
    38581 aagattataa atagaagtca tgaggaagga atatctcctg aagaagttgc ggctaagtat
    38641 ataaaagaat attttgtaga ctgtgatggg ctaggaataa aaagagctac tgttcatcct
    38701 caggttacag ataatataca acagattata gagtttataa aagagttgga agataaggga
    38761 tatgcatatg cagtaaatgg tgatgtatat tttgatacaa ataagtttga aggttatgga
    38821 aaactttcag gtcaaaaaca agaagattta gaggcagggg ctagaattga ggttaatgac
    38881 caaaaaagac atcctatgga ctttgttctt tggaaggcaa aaaaagaagg tgagccagga
    38941 tgggatagcc cttggggaga aggtagacca ggatggcata tagaatgttc tgttatgtct
    39001 aagagatatt taggtgaaac aattgatata catgcaggtg ggcaagattt aacattccca
    39061 catcatgaaa atgaaatagc tcaaagtgaa gctagaagtg gaaaaacatt ctcaaaatac
    39121 tggatgcata atggatatat aaatataaat gatgaaaaga tgagtaaatc aaaaggtaat
    39181 ttctttacag taagagatat atcaaaatta tatgatttag agatagtaag atttttcatg
    39241 ttatcagcac attatagaaa tccagtaaac tttagtgatg agatgttaaa tcaagctaaa
    39301 gcaggtcttg aaagactata taatactaaa gaaaaattag aatttacgct aagtaattta
    39361 gtagaatctc ctttaacaga aaaagaagta gagcttgtta aagaattaga tgactttaga
    39421 caaaaattca tagatgctat ggatgatgat gttaatacag cagacgcagt aagtgtaata
    39481 tttgaattag ctaagttaat aaattctaat gtagatgaaa attcttcttt ggagtttgct
    39541 aaaaaatgct tagatgaatt taatgaactt acaggagtat taaatattgt aaataagaaa
    39601 aaggatactg tattagataa agacattgaa gaattgatac aaaaaagaac tgatgcaaag
    39661 aaaaataaag agtttcaatt agctgatgat attagacaac aattactaga tatgggaatt
    39721 gtattagaag acacaagaca aggtgttaag tggaaaagga tataaaaatg gaaaaaactg
    39781 aattagttac tatgtcacca ttagttttag catacttagg tgatacagtg tatgagacat
    39841 atataagaga atatttaatt agacagaata cacaaagaaa agttaatgat ttgcataaac
    39901 tagctataaa gtatgtaaaa gctaaagctc aggcaactat aattcatgaa attgaaattg
    39961 agttaactga agaagagagt aaaatttata aaaggggaag aaatcaaaag tcaaatactt
    40021 ctcctaagaa tgcagatatt atagactaca aacatgcaac tgggtttgag gcattagtgg
    40081 gatatttgta tttaaataat gaaatagaga gacttcaata tattatcaat aaaggaatca
    40141 aaattattga aagagatatg taaatattaa agagtgttgt cttaataata agtaataagg
    40201 caacactttt tttataacta atgtataata aatatataga aattagtaat gagaaaggat
    40261 aaaaagttat gaaagtaaaa ttaatatcac atacacctga accagaaaaa gtaatagcta
    40321 tggcagctaa gctatgttat tcaccagttg ggacagacga aatagaaaaa gacttaacag
    40381 atgaaagtat agagaaattt ttaaatatgt tattaagtat aggtcatggg tcaatattag
    40441 aacatgcttc atttacattt tcaatagaag gtatttcaag ggcttgttca catcaaattg
    40501 ttagacatcg tatagctagt ttttcacaac aaagtcaaag atatgttaaa ttagaacaat
    40561 ttgagtacat aattcctcca gaaatagaaa aaatagaaaa agcaaaagag ttatttatag
    40621 actccatgaa aaaagaccaa gagaattatg ataagttagt tgaaatattg tttgaaaatc
    40681 attataatga cctaataaaa aacggtaaaa atgagaaaac agctaaaaga caagctgaaa
    40741 agaaagcaat agaagatgct agatacgtat ttccaaatgc atgtgaaaca aaaatggtat
    40801 ttactataaa tgctagaagt ttgtttaatt tctttgaaca tagatgctgt gaaagagcac
    40861 agtgggaaat aagaaatttg gctgtggaga tgttaaaaga ggttaaaaag gttgctccta
    40921 tattatttaa aaagactggt ccaagttgtg taaatggaag ttgtccagaa ggaactatga
    40981 cttgtggaga tatagttcaa gttagagaaa aatttaaggc cttgtaggag gtgaataatt
    41041 tggcgagtat agaaggaaga aatccggtaa tagaagcaat aaaaagtgac agagaaatag
    41101 ataaaatatt aattgcaaat tcagctaaag aaggttcaat taagaaaata ataggaatgg
    41161 ctaaagataa gaatataatt attcagtatg ttgataaaca taagctagat gaagtaagta
    41221 caagtcattc acatcaaggt gtaatagctt atgcaagtga gtataagtat tatgaattag
    41281 atgagctaat agatttagca aagaataaag atgaagaccc atttttcatt atattagatg
    41341 agataacaga cccacataat ttgggttcaa taataaggac agcagatgca gtaggagcac
    41401 atggagttat cattccaaaa agaaggtctg tacacataac tcctgtagtt gccaaagcat
    41461 ctgctggagc agtagaatat atgccagttt gcaaggtaac caatatagtt aatacaataa
    41521 aaagactcaa agaagaaggg ctgtggattg ctgcagctga tatggatgga gaaacttttt
    41581 ataaacaaaa tcttactggt cctcttggtg tagtaattgg aagtgaaggt tttggaatat
    41641 ctagattggt taaacaaaac tgtgacttta tagtaaaaat gccaatgata ggtaatgtta
    41701 catctttaaa tgcatctgta gcaggtggaa tacttttata tgagatattc agacaaagac
    41761 tggataaaag taaataggca tgaaaaaaaa tataaatcat tacttaataa tagatggcta
    41821 caatattata aatgcgtggg acaatttgaa agaactggct aaagaggact tagaagattc
    41881 tcgagaaaag cttattgatg acattataga attttctgag tttatgggtt ataagactat
    41941 aatagttttt gatgcttata atgttaaaaa ttctcgagaa aaagttgaaa aaagaaaaca
    42001 cataacaata gtttatacaa gagaacacca aacagcagat agttatatag agaaatttat
    42061 aacttcttta tcaaagtatg atgatgtaaa agtagccact aatgactatg cagaacagca
    42121 aatgatttta ggaaaaggtg ctactagaat gtctgcaaga gaattaaagt tagagttaga
    42181 tcgttccaag aataaaatga aggaaaaaaa tatcggtttg aggaaaaaaa ttcagcgaaa
    42241 ttggttggag gaaaggttag ataaagaaac attgtcgaaa cttgagaaca ttcgtagaaa
    42301 gcgttgaaat tactaggttc tttagactat aatataccta taaatttgtt ttatatatgg
    42361 gggagattta catgttggta gcaaaagaaa aaagttatga gttagtggac aattgtcagc
    42421 aggatgagta taacattgta ttaagagcaa gtgaagggga taaaatagca ctagagtaca
    42481 ttattactaa atacagaaat tttgtaaagg caaaagcaaa gtcatatttt ttaattggag
    42541 cagataaaga agatataata caagaaggaa tgataggcct ttataaggca gttagagatt
    42601 ttgatggaag taagaccaat tcatttaaat gttttgcgga gatatgtata acaagacaaa
    42661 taataactgc tataaaaact gcaacaagac aaaaacatat acctttaaat tcatatgttt
    42721 ctttgaataa accaatatat gatgaagagt cagacagaac acttttagat attatagcta
    42781 caagtatagt aacagatcca gaagagctta taattagtaa agaagagtta aaaaatatag
    42841 aatcaaaaat gaacgaattg ttaagtgact tggaattaga agtactagaa ttatatttaa
    42901 atggaaagtc ataccagttt atagcggaca agcttaaaag agatgtaaag tcaatagata
    42961 acgctttaca aagggttaag agaaaattag aaaaacatct tgaaaacaga aatgattaat
    43021 agtaaaatac ttaccataag cttattgtga gcaaaattaa tttatatcga aagataaggg
    43081 aggaaattca aaatggctaa agctaaatac gaaagaacaa aacctcatgt taatataggg
    43141 acaataggac acgtagacca cggtaaaact acattaacag cagcaataac aaaaacatta
    43201 tatgacagat atcaattagg agaagcagta gatttcgcaa acatagataa agctccagaa
    43261 gaaagagaaa gaggaatcac aatatcaaca gcacacgttg agtatgaaac accaaataga
    43321 cactatgcac acgttgactg cccaggacat gctgactacg ttaagaacat gataacagga
    43381 gcagcacaaa tggacggagc aatattagtt tgttcagcaa cagatggacc aatgccacaa
    43441 acaagagagc atatactatt atcaagacaa gttggagtac catatatagt agtattctta
    43501 aacaaatgtg acatggtaga tgatgaagag ttattagagt tagtagagat ggaagtaaga
    43561 gatttattaa cagaatatga tttcccagga gatgacactc caatagtaag aggttcagca
    43621 ttaat
//
LOCUS       DAEQAF010000023        43113 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.024, whole genome shotgun sequence.
ACCESSION   DAEQAF010000023 DAEQAF010000000
VERSION     DAEQAF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43113
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.024"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..1807)
                     /locus_tag="KRN00_001358"
     CDS             complement(<1..1807)
                     /locus_tag="KRN00_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827225.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYDIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGENFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINN"
     gene            complement(1990..3465)
                     /gene="spoIVA"
                     /locus_tag="KRN00_001359"
     CDS             complement(1990..3465)
                     /gene="spoIVA"
                     /locus_tag="KRN00_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBH1827226.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(3637..4932)
                     /locus_tag="KRN00_001360"
     CDS             complement(3637..4932)
                     /locus_tag="KRN00_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1827227.1"
                     /translation="MSVEVNKPSIWKNFKVLIILFVAGAFIYALPYLKNYYYDTFAQA
                     FNLTNTQMGSLGSIYGLLAMVSYLFGGFLADRISARKLLSGSLIITGISGLVLTLYPP
                     YIVVFLIHALWGITTILTFWPALVKAVRMLASENEQGKAFGFMESGRGITNAIHLSLV
                     LILFGYISSKVSDKSGLTAIIVLYSVINVIVGVLVFFKLKDNEKEVSAKFDKEAFFAV
                     IKMPHTWIITIIMFCSYSANMSFYYFTPYSTEAFGATVVFASAISILAQYCRPIASAA
                     SGLLGDKVGSSKIISYGFILMIAGLLGVIFTPTKSSMIYILLIGCVAIYVSMYAIQGL
                     HYSLLEEGNYSLSISGTAIGIVATLGYLPEVLCPLAAGKILDAFPGVTGYRYYFIVLT
                     IVAIIGLVFTFIWMNMTKERRKELIEMNNNSNENATKVS"
     gene            complement(5116..6525)
                     /locus_tag="KRN00_001361"
     CDS             complement(5116..6525)
                     /locus_tag="KRN00_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1827228.1"
                     /translation="MKKKIGFWDLVFMNISALFGIRWIAKSTASSFGLGLGSIPVWLL
                     FAFIFFVPASLICAELAATYPKDGGLGEWVKQAYGEKWGFMVSWLNWTSKIFWYSSFL
                     TFLAINIAYMLGNPDLSNNKMFILALSLIIFWLLSLVSTRGMAFGKFFTNTGALGSTI
                     PAILLIVMAFMSVVILKKAPSASIYTIQNIIPKIDANSLVSISAIIFALSGAETTANF
                     ITEMDNAKKNFPKAILTVAVLIGGIYILGSVAITMILPPDKIAASTGILDALAKVAQD
                     LGIGSWFIRIVAFGITLSVLGALILYIAGPVKMLFGNVREGVFPKQLTVTNKYNIPSN
                     AVIVQAIIVSLLLVGTNLLPSVDNIYNVLVTMTALTALFPYVLLFTSYIRLRKTRPNE
                     ERPYSIAKSDSVCINIARMVLVVTVVGILFSTAPVMETLKDNIIYEIEMIGGGLFVII
                     TGLMLWKNYEKKISNNSGR"
     gene            complement(6577..7716)
                     /locus_tag="KRN00_001362"
     CDS             complement(6577..7716)
                     /locus_tag="KRN00_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1827229.1"
                     /translation="MSNNMRLERLRKYMNEKSIEIALIFEPDNQFYISGFKAITYSRP
                     IVTVVTQDKIELIVPGLEELHAKEVAKVDNVYVYYEIPEMKEHGISHKHYLDIILNKY
                     PKGTTVGIEKDIVSASFSEYITDKSFAIKDVGSKIFEMRYVKDAKEIEFLKIAGYLSD
                     IGIKGSLENVRVGMSELEFDVAGDNALLKYVSENYPDTYIGFANWTCSGIDRTAQPHL
                     DSNTRILQRGDIVIHSRQVWYENYRAENERTFIIGKPTERQKEVFKIAVEAQQAGLDT
                     IKAGIPARMVDEAARAVVAKYGLELYSNHRIGHGLGLSEHEEPYLRFDNELILEEGMV
                     FSMEPGIYIPGVGGFRHSDTAIVGKNGATIITNYPRSVEELILDI"
     gene            8035..8685
                     /locus_tag="KRN00_001363"
     CDS             8035..8685
                     /locus_tag="KRN00_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1827230.1"
                     /translation="MTNKELQKKRILMYFIEAAQNIMENEGIENITLRKVADMAGYNS
                     STLYKYFKNLDHLISFASIKYFKDYNLNISRCIENVNDEYKKYIIMWKLFCKHSFDNA
                     QAFYQVFFNLSSDELSYITKQYYDMFPEDLGIHDSDISLMITGESIKERNKILLNNLV
                     DTGYIPAKDLDIINDIIISFYQNLLFLKKNTGKNSDDDELTMKMISSIEYIIKHAK"
     gene            complement(8842..9861)
                     /locus_tag="KRN00_001364"
     CDS             complement(8842..9861)
                     /locus_tag="KRN00_001364"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH1827231.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(9892..10506)
                     /gene="plsY"
                     /locus_tag="KRN00_001365"
     CDS             complement(9892..10506)
                     /gene="plsY"
                     /locus_tag="KRN00_001365"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBH1827232.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(10541..11860)
                     /gene="der"
                     /locus_tag="KRN00_001366"
     CDS             complement(10541..11860)
                     /gene="der"
                     /locus_tag="KRN00_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBH1827233.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(11894..13222)
                     /locus_tag="KRN00_001367"
     CDS             complement(11894..13222)
                     /locus_tag="KRN00_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBH1827234.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEMGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPENILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     EALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(13460..13660)
                     /locus_tag="KRN00_001368"
     CDS             complement(13460..13660)
                     /locus_tag="KRN00_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827235.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(13662..14594)
                     /locus_tag="KRN00_001369"
     CDS             complement(13662..14594)
                     /locus_tag="KRN00_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH1827236.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(14639..15571)
                     /locus_tag="KRN00_001370"
     CDS             complement(14639..15571)
                     /locus_tag="KRN00_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBH1827237.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYDLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(15626..16915)
                     /locus_tag="KRN00_001371"
     CDS             complement(15626..16915)
                     /locus_tag="KRN00_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1827238.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(16944..17636)
                     /locus_tag="KRN00_001372"
     CDS             complement(16944..17636)
                     /locus_tag="KRN00_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827239.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(17651..18412)
                     /gene="pgeF"
                     /locus_tag="KRN00_001373"
     CDS             complement(17651..18412)
                     /gene="pgeF"
                     /locus_tag="KRN00_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBH1827240.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(18409..18870)
                     /gene="nrdR"
                     /locus_tag="KRN00_001374"
     CDS             complement(18409..18870)
                     /gene="nrdR"
                     /locus_tag="KRN00_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBH1827241.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(18892..19155)
                     /locus_tag="KRN00_001375"
     CDS             complement(18892..19155)
                     /locus_tag="KRN00_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBH1827242.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(19259..20032)
                     /gene="sigG"
                     /locus_tag="KRN00_001376"
     CDS             complement(19259..20032)
                     /gene="sigG"
                     /locus_tag="KRN00_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBH1827243.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(20124..20846)
                     /gene="sigE"
                     /locus_tag="KRN00_001377"
     CDS             complement(20124..20846)
                     /gene="sigE"
                     /locus_tag="KRN00_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBH1827244.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(20871..21743)
                     /locus_tag="KRN00_001378"
     CDS             complement(20871..21743)
                     /locus_tag="KRN00_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBH1827245.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(22033..23307)
                     /locus_tag="KRN00_001379"
     CDS             complement(22033..23307)
                     /locus_tag="KRN00_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBH1827246.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(23591..24748)
                     /gene="ftsZ"
                     /locus_tag="KRN00_001380"
     CDS             complement(23591..24748)
                     /gene="ftsZ"
                     /locus_tag="KRN00_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBH1827247.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(24938..25291)
                     /locus_tag="KRN00_001381"
     CDS             complement(24938..25291)
                     /locus_tag="KRN00_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBH1827248.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(25390..26064)
                     /locus_tag="KRN00_001382"
     CDS             complement(25390..26064)
                     /locus_tag="KRN00_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1827249.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(26069..26767)
                     /locus_tag="KRN00_001383"
     CDS             complement(26069..26767)
                     /locus_tag="KRN00_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1827250.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKAIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(26790..27530)
                     /locus_tag="KRN00_001384"
     CDS             complement(26790..27530)
                     /locus_tag="KRN00_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBH1827251.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(27800..29026)
                     /gene="murG"
                     /locus_tag="KRN00_001385"
     CDS             complement(27800..29026)
                     /gene="murG"
                     /locus_tag="KRN00_001385"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH1827252.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSASKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(29044..30174)
                     /gene="spoVE"
                     /locus_tag="KRN00_001386"
     CDS             complement(29044..30174)
                     /gene="spoVE"
                     /locus_tag="KRN00_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBH1827253.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(30226..31581)
                     /locus_tag="KRN00_001387"
     CDS             complement(30226..31581)
                     /locus_tag="KRN00_001387"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBH1827254.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(31600..32568)
                     /locus_tag="KRN00_001388"
     CDS             complement(31600..32568)
                     /locus_tag="KRN00_001388"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBH1827255.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(32609..33982)
                     /locus_tag="KRN00_001389"
     CDS             complement(32609..33982)
                     /locus_tag="KRN00_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBH1827256.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHAYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(34149..36128)
                     /locus_tag="KRN00_001390"
     CDS             complement(34149..36128)
                     /locus_tag="KRN00_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBH1827257.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIEAFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(36140..36487)
                     /locus_tag="KRN00_001391"
     CDS             complement(36140..36487)
                     /locus_tag="KRN00_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827258.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(36968..37903)
                     /gene="rsmH"
                     /locus_tag="KRN00_001392"
     CDS             complement(36968..37903)
                     /gene="rsmH"
                     /locus_tag="KRN00_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBH1827259.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(37933..38679)
                     /locus_tag="KRN00_001393"
     CDS             complement(37933..38679)
                     /locus_tag="KRN00_001393"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBH1827260.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVIGGIIAHVYLSKKNKNNISEE"
     gene            complement(39073..40359)
                     /locus_tag="KRN00_001394"
     CDS             complement(39073..40359)
                     /locus_tag="KRN00_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1827261.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LDYLDIIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(40374..41639)
                     /locus_tag="KRN00_001395"
     CDS             complement(40374..41639)
                     /locus_tag="KRN00_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBH1827262.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINILRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            41955..43052
                     /gene="ychF"
                     /locus_tag="KRN00_001396"
     CDS             41955..43052
                     /gene="ychF"
                     /locus_tag="KRN00_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBH1827263.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
BASE COUNT        13438 a         7937 c         4521 g        17217 t
ORIGIN      
        1 tattatttat tattccatca taatcactta tatttgactt atttttattt gtatcttgat
       61 ttttgttaga aatactttcc ctataaggaa aagaatgttc attggtacca aatactgatt
      121 ttgagcttaa atcataatta tcatcatttt ctgtaattga atttttattg taaaatcctt
      181 tttctttatc agaattattt tctttattac cgtctttagg tatatcatga ggatttttat
      241 tttcattgct atcagtactt gattctacat catctttagg agtatttggt tgtttctcat
      301 cagaattatc attttcatta ttattatttt cattattatt gttttgattg ttattactat
      361 cattattttc atttccatta ttcccatctt gattgttatc atcctcatct ctatccgggt
      421 cgtctctacc tcctcctcca cggtcaccat caatatcatc attttcccgt tcatcatctg
      481 gtgtctcttg gttgtctccg cctcccatta taaatcctgg tttaaaaact atatttgaat
      541 acccttcttt taatcctcct accactttta ctctaaaaca acgcaactta aaatcttcaa
      601 aaaaaagtat agcttgatct ctaatatcct cctgttcttc agatatccaa ttgattccat
      661 cgcttgaata ttcaacaaaa accttacttg cactatacgg catatcataa aataaaacag
      721 ctacatatcc attttttgta ttttgaaatt ccagttccaa attgtctatt ggttttttct
      781 ctataacaga tacattcaaa ataggaacta catcatcatt tattataatt ttttctttat
      841 ttaacatttc tgttttaaac tttcctgtta tattaaaatt ttctcccttt tccaactttt
      901 cataataatc agtaaaatcc cattctacat ctatatcaag tcgattacca ctagatgttt
      961 ctaataccat atatttggga aattttatat tttctatttt atcatcttta cttactttta
     1021 tttcatcact aaatacacca attcccctat gacaacattt cacaatatca tagccagaat
     1081 cttcagctat agagggtata agctcattat aatcatcaat tatataaact ttcttacttt
     1141 ctgatataat tgattgtgcc aacttattat tatctcttag taacccactt tcattgttgc
     1201 tactatatgc ttttattgaa gtttcttcta tctcaacatc acctttagaa taaacaccta
     1261 tagcatgttc tccattcact tcaatatcct tatttagtat tctaatatca ttttcagtat
     1321 aaattcctat tgcatctttc ccatttgcct ttattttttc aacagattcg taggatgatt
     1381 taatatgtaa gtctcctcct tcttcaacgt ataaggctgt cccatcagta gcaattatgt
     1441 tgtttatacc aatacttata cttccaccat tttctatatg tattactcct tcttttcctc
     1501 cttcacctat tatattcaat tcattatcat caataataaa tctcccatga ttttttatca
     1561 atattttata tttgttggta tctattgtaa aattactgtc ataaggaata taaaatctaa
     1621 actcttcatc tattaccata tcacaagaaa gagtataaac tatttcttct ttattatttt
     1681 tattttcttg aacccacctt tcaaaatctt caagacaatt ttcctcttgt ccaaaaactt
     1741 tatgtggaaa acttataaaa cacaaaacta ttatactcat aaaaataaat atctcatact
     1801 ttttcatctt acactcctag aaatttttag ctttgaaaca atcctgtcga aacatatact
     1861 tcacccacta taatttttcc acaattatca attattgtca atttatataa gtatctttat
     1921 taattgttat aaataaaaag ctacttacta aagcaaacag acgtttcact ttaataagta
     1981 gctatatttt tataacaaaa tagttataat attagaactt ccttcattta caattttttg
     2041 taaagtcttt tgcattttaa ctcttatctc ttctggcata gtatataatt tactttgtaa
     2101 ttgctctttt actaagtcat gtagtgactt accaaacata tttgattccc ataaatctgc
     2161 tggttgctct tcaaatactt ccataagata ttttatcatc tcttcacctt gattttgatt
     2221 tccaactatt ggagaaacct ctgtagatat atctgctttt ataatatgaa gtgatggtgc
     2281 attggctttt aacttgatac catattgttt tccttgtttc attatttctg gttcttccag
     2341 actaagttct tctaaggaag gagctactac tccatatcct tttatcttgg catctattaa
     2401 agcactttct attttatcat actcattttt aactttagat agtctagtta tcagactaag
     2461 cagttgataa tctccttcaa ttttaaatcc acttttttct tcaaggacat tatagaataa
     2521 atcttgcttt gtctgtaaat caatatttat aacaccttct cctagctcta cattatcaac
     2581 acctgtatct tccaaaaact ctaactcaga aaatccttgt ataatacctt ctatatccct
     2641 tattttacct atatctataa tactttgttt taatgttgtt attatgctac tttttatcca
     2701 atgatttctt tcaagacctt caacccattt tggtaagttg attcttattt ctgtaagtgg
     2761 aaaatcatat aatacagctt ccataacctc ctctatatct tcttcttcca tttcaaccac
     2821 attcattgga agaactggaa cttcatactt ttcttccaat tcacttctaa gcatactcgt
     2881 ttcctcactt tttggactta acgtatttaa aaccactgca aatggttttt taagattttt
     2941 caattcttgt ataactctct cttctggttc tacatagctt tttctgtcaa ttccagtaac
     3001 tgaaccatct gtcaagacaa ctatccctat tgtagaatgg tcttttataa cttttttagt
     3061 tcctatctct gctgcctttt caaatgtcat agcttcttgt gaccaaggag tggatactaa
     3121 tctttgtttt ccaccttcct catgccctaa agctccttca actatgtatc caacacaatc
     3181 taccattctt acttttaaag atactgtgtc ttttattttt atttctacac catctgctgg
     3241 tacaaatttt ggttctactg tcattatcgt tttacctgaa ccactttggg gtatctcatc
     3301 tcttgttcta tcctttttaa attcattgtc tatattaggt ataaccaact tttccataaa
     3361 ttttcttata aaagttgatt ttcctgttct tacaggtcca actactccaa tatatatatc
     3421 cccctgagtc cttttggata tatcttcgta tatgttatta ttcatattat tcctcctata
     3481 catctaatct tattaaatta tatttagagt taagggttaa tattcttaaa atagaaaaat
     3541 aaagaccagc aatattaatt taatttacat atagaaattt gtaaatttca atgtaaatta
     3601 aattaatatt gctggtccaa atagtagtgt attatattaa ctgactttag tagcattttc
     3661 atttgaatta ttattcatct caataagttc tttacgtctt tcttttgtca tgttcatcca
     3721 tataaatgta aacaccaatc caattatggc tactatagta agaactatga agtagtacct
     3781 atatccagtt acacccggaa atgcatccaa tatcttccct gctgctaaag gacaaagtac
     3841 ttctggaaga tatcctaacg tagcaactat tcctatagca gttcctgata ttgataatga
     3901 ataattacct tcttcaagta acgaatagtg taaaccttga attgcataca tagatacata
     3961 tattgcaaca catccaatca atagtatata aatcatagat gattttgttg gtgtaaatat
     4021 tacacctaaa agacctgcaa tcataagtat aaatccataa gatataatct ttgatgaacc
     4081 aactttatct ccaagtaatc cagaagcagc tgatgctatt ggtctacaat actgagctaa
     4141 tattgagatt gcagatgcaa acaccacagt agctccaaat gcttcagttg aataaggcgt
     4201 aaaataataa aatgacatat tagctgaata tgaacaaaac attattattg ttattatcca
     4261 tgtatgaggc atttttatta ctgcaaaaaa ggcttcttta tcaaattttg ctgatacctc
     4321 tttttcatta tcctttaatt tgaaaaatac taatactcca actattacat ttattaccga
     4381 gtataatact ataatagctg taagaccaga tttatcactt acttttgatg aaatataccc
     4441 aaatagtatc aatactagag atagatgaat tgcattggta attccacgac cactttccat
     4501 aaatccaaaa gcttttcctt gttcattttc agatgctaac attctaacag cttttacaag
     4561 agctggccaa aaagtaagta ttgttgttat tccccataag gcatggatta aaaacacaac
     4621 aatatatgga ggataaagtg ttaatacaag accagatatt cctgtaataa ttaaagaacc
     4681 tgaaagcaat tttctggctg aaatacggtc tgctaaaaaa ccaccaaaaa ggtatgatac
     4741 cattgcaagt agaccataaa tgcttcctaa gcttcccatt tgtgtatttg taagattaaa
     4801 tgcttgtgca aaagtatcat aataataatt ctttaaatat ggtaaagcat atataaatgc
     4861 tcctgctaca aagagtatta tcaagacttt gaaatttttc caaatgcttg gtttatttac
     4921 ttcaactgac atacttcctc cttatgtaaa tacctgtaaa ttttcatgat aattaattat
     4981 tgcttattgt attgtttatt caatatttcg gaatatttat taatatatta ggttaatcta
     5041 tcaataattt atggtgagtt atgagctaaa agtaaactct tttagctcac cataataatt
     5101 atatttttat ttatactaac gtccagagtt attagatatc tttttttcat agttcttcca
     5161 tagcattaaa cctgttatta taacaaaaag acctcctcct atcatttcaa tctcatagat
     5221 tatattatct tttaaagtct ccataactgg tgccgttgag aaaagtatgc caactacagt
     5281 tactacaagt accattctgg caatattgat acaaactgaa tcactttttg caattgaata
     5341 tggtctttct tcatttggtc ttgtctttct aagtctaata taagatgtaa aaagcaagac
     5401 atatggaaat aatgctgtta atgctgtcat agtaacaaga acattgtata tattatctac
     5461 tgatggtaat aagtttgttc ctacaagaag tagactcact attatagcct gaactattac
     5521 tgcatttgat ggtatattgt atttatttgt aacagtcaat tgcttaggaa atacaccttc
     5581 tcttacattt ccaaaaagca tctttactgg acctgctata taaagtatta atgctcctag
     5641 tactgataaa gttattccaa atgctactat tcttataaac caacttccta tacctaaatc
     5701 ttgtgcaact ttagctaatg catctagtat ccctgtagat gctgcaattt tatctggagg
     5761 aagtatcatt gttattgcta ctgaacctaa gatatagatt cctcctatta aaacagccac
     5821 agttaatata gctttaggaa agtttttctt agcattatcc atttcggtta tgaaattagc
     5881 agtcgtttca gctcctgata atgcaaatat tatagcagat atagaaacta atgaattggc
     5941 atctattttt ggtattatat tttggattgt atatatcgat gctgatggag cttttttgag
     6001 aataactaca gacataaatg ccatcactat aagtaatata gcaggaattg tagaacctaa
     6061 tgctcctgta ttcgtaaaaa attttccaaa tgccatccca cgagtactta ctaaggataa
     6121 cagccaaaat attatgagtg aaagtgctaa aataaacatc ttattgtttg ataaatctgg
     6181 atttccaagc atatatgcaa tatttatagc taaaaatgtc aagaaagaag aataccaaaa
     6241 tatctttgat gtccaattta gccatgacac cataaatccc cacttctctc cataagcttg
     6301 tttaacccat tctccaagtc caccatcttt tggatatgtt gcagccaatt ctgcacatat
     6361 aagtgatgca ggaacaaaga atataaaagc aaacaataac caaactggta tagaaccaag
     6421 acccaatcca aaactagagg cagtagattt agctatccat ctaatcccaa atagtgctga
     6481 tatattcata aatactaaat cccaaaatcc aattttcttt ttcactgtaa ttcctccaat
     6541 ttcaaattta ttcaaactca tacactatgt attgatttaa atatcaagta taagttcttc
     6601 aacacttctt ggataattag ttataattgt agcaccattc ttacctacta ttgctgtatc
     6661 tgagtgtcta aatcctccaa ctccaggtat atatatccct ggttccatag aaaataccat
     6721 tccttcttct aatattaatt cattgtcaaa tcttaaatat ggctcttcat gttctgataa
     6781 acctaaacca tgaccaattc tatgatttga atataactct agaccatact ttgcaacaac
     6841 agctcttgct gcttcatcca ccattcttgc tggtatacca gcttttattg tatctaatcc
     6901 agcttgttga gcctctactg caatcttaaa cacttctttt tgtctttctg ttggtttacc
     6961 tataataaaa gttctttcat tttctgctct atagttttca taccaaacct gtctactatg
     7021 tattactata tctcctcttt gaagtattct agtattagaa tctaaatgag gttgtgctgt
     7081 tctatcaatc cctgaacaag tccagtttgc aaatcctata tatgtatcag gataattttc
     7141 agaaacatat tttagtaaag cattatcccc tgcaacgtca aactccaatt cactcatccc
     7201 aactctaaca ttttctaaag acccttttat tcctatatca gataggtaac ctgctatctt
     7261 caaaaattct atttcttttg catcttttac atatctcatt tcaaatattt tacttccaac
     7321 atctttgata gcaaatgact tatcagttat atactctgaa aagcttgcag atactatatc
     7381 tttttctatt ccaacagttg ttcctttagg gtatttattt aaaattatat ctaagtaatg
     7441 tttatgtgat attccatgtt ctttcatttc tggtatttca taatacacat atacattatc
     7501 aacttttgca acttctttag catgtaattc ttctaatcca ggtactatta attctatttt
     7561 atcttgagtt actactgtta caattggtct agaataagtt attgctttaa atccactaat
     7621 ataaaattga ttgtctggtt caaatattaa agcaatttca atgctttttt cattcatgta
     7681 ctttctcaat ctttctagtc tcatattatt tgacataatg cacctctttc ttaatattca
     7741 gataatttat tcaatacaac aaggatgaat atattatttt aaaattctta atatttttag
     7801 tacttgtcgt atttgtatgt aaattaattt tatttgtgat tattttatca taatcatgat
     7861 tattttgtca atcatgattt tattttaaaa aattttttat attctagtga ttttaaatta
     7921 tctaaaatat aacgagtata cattgtattt tgtaatatta ttcttgattt atggtaagtt
     7981 taatgataaa atcacgatta tataaactat attgattatt tgtaggtgaa taaaatgaca
     8041 aataaagaat tacaaaagaa aaggatattg atgtatttca tagaagctgc tcaaaatatt
     8101 atggaaaacg aaggtataga aaatattaca cttcgtaagg ttgcagatat ggctggctat
     8161 aatagttcaa ctctatataa atactttaaa aatttagacc atttaatatc atttgcatct
     8221 ataaaatatt ttaaagatta taacttgaat atttcaagat gtatagaaaa tgtcaatgat
     8281 gaatataaga aatatataat tatgtggaaa ttattttgta agcattcttt tgataatgct
     8341 caagcttttt atcaggtatt ttttaacttg tctagtgatg aacttagcta tataacaaaa
     8401 caatattatg atatgtttcc agaagattta ggtattcatg atagtgacat atctttaatg
     8461 attacaggag aaagtataaa ggaaagaaat aagatactat taaacaatct tgtagatact
     8521 ggatatatac cagctaaaga tttagacata atcaatgata taattatttc tttttatcaa
     8581 aatctattat tcttaaaaaa gaacacagga aaaaattctg atgatgatga attaactatg
     8641 aaaatgattt cttctattga atacataata aaacatgcta aataaaatta aaatatggct
     8701 gtctcaaaat agagataagc cttttttatt gttgaaataa taaaaatata tttaatttca
     8761 tataaaaaag agtgcctcgt aaactaaaaa gttcattttg agacacccct aaaacaaatt
     8821 tattatttat tatacaatag tttatatatc atcacctaaa actacttctt ccatttcatg
     8881 ctttttactt ctcatcatta gttctattcc aacttcttta ggatttgaac ctttctttat
     8941 tacagaatat atagcattag ttataggcat atctatatct aatttttcag caacatcatg
     9001 tgctacttca gtagcagtta tgccttctac aaccatcttt acttctttta aagtatcttc
     9061 taaactcata cctttaccta tgagtatacc agctcttcta tttctactat gcatacttgt
     9121 acaagtaact attaaatctc caatacctga aagacctgca aaggtagaca tattagctcc
     9181 catagcaatt ccaagtctgc tcatttcact aatacctctt gtcataaggg cagcttttgc
     9241 attatcacca taccctaatc cgtcacatat cccagctcca aatgctataa tattttttaa
     9301 tgctcctcca agttctactc caactatgtc tggattcgta taaactctaa gtttagggct
     9361 cataaataaa tcttgtatca tctgtgctat ttttaaatct ttagaagcaa ctactacggt
     9421 agtaggaata tcccttgcta cttcttcagc atgagatggc ccagatagta ttacatatgg
     9481 attttgtggt aattcttctt cacagacttg agataatcta agcccagtcc ctttttcaag
     9541 acctttagct acattaacaa taacttgtcc ttcttttata aatggtttta ttttttggca
     9601 agtacttctt acagcctgtg atggaactgc taaaactatt accttacaat cttttatagt
     9661 tttttctata tcagtactta tagttatatt atttggaaat aatactcctg gtaaatagtc
     9721 tgtattttct ttagttctgt ttattttttt agcttgttcc tcttttcgag tccacatgct
     9781 cacatcatta cctttttttg caagccctaa agctaatgca cttccccagc ttccagtacc
     9841 taatacacat actttctcca tgtttaacac cacctgagta taatatattt actattcttt
     9901 cttttgacca atttttctct ctgtcccatt taataatcgc tttatatttg ctctgtgatt
     9961 atatattact gatgcagtta agaacagagc tactattaaa ccagctttat tttttaccat
    10021 aatcataaat attggtgaac atcctattcc tacaacagaa cccaatgaaa catactttgt
    10081 tatagctacc accaatataa atactgctag acacattagt gttattactg gatttacagc
    10141 tagcattgcc cctagtgaag ttgcaacacc tttgcctcct ctaaatccta aaaccgctgg
    10201 ccaattatga cctgctacaa cacatataac tgccagatat ccagctaaaa gagtatctat
    10261 tccaaccaat cttgctgcaa attctgatat taaaacagcc attacacctt taagaacatc
    10321 acctaaaaat gtcattgccc ctgctctttt tccaagtgtc ctaagtacat ttgtcgaacc
    10381 tgcattacca gaaccttgag tccttatatc aaccccagca attcgctttg caactatgta
    10441 tgaggtagat atatttccta aaagatatgc aactacagca ataattatat aactaaatat
    10501 ctccactgaa tttcccccct ttagttatat tttaagatat ttatttttta tttttttgtc
    10561 tatactcaaa ctttatggaa gttccttcaa atccaaaatt ttctcttatc ttattctcaa
    10621 ggtatctttg atatgagaag tgagttaaat ccttatcatt tataaacaat gtaattttag
    10681 gaggtctaat gtcagtttga gtcccatagt aaatttttaa tcttctacct ttgtcagatg
    10741 gtggttgatt taacattaca gcttctccaa ttacttcatt cagtgctgaa gttgatattc
    10801 tcttagaatg ttcatttgac acatattcaa ctgtatctag tatcttgttc attctttgat
    10861 tagtttttgc agaaacaaat acgattggag catacatcat aaatggaaat ttttctttta
    10921 tatcttttgt gtaattactc atagtcttat tatctttctc tattaaatcc catttattga
    10981 ttacaaatat gcatcctttt ccttcatcat gtgctatacc tgcaaccttt gtatcttgtt
    11041 ctgttacacc ttctaaggca tctattacta tcaatactac atctgctcta tctacagcac
    11101 tcatagctct tattacactg tatttttcta ttgtctcata tattttactt tttcttctaa
    11161 gccctgctgt atctattaga agaaatttct gtccattttt ttcaaaataa gtatcaattg
    11221 cgtctctagt agttcctgca attggactta caattactct ttcttctcca agtatcttat
    11281 tgagtataga actttttcct gcatttggtt tacctgttat agctactctt attatatctt
    11341 cttcatactc tgtatctaat cctgctggaa aattttcaac tatctcatct aataaatctc
    11401 caaatcccat actattggct cctgaaactg caaaaggcgt tccaaatccc aactcataaa
    11461 aatcgtatat attatcaaat tgactttgac tatcaatctt attaaccact aagattactg
    11521 gtttttttgt ctttctaagc aattgtgcaa tttctttatc agcagctgtt attccagctt
    11581 taccatcaac tataaaaagt attacatgtg acatgtccat tgcaagcatg gcttgatttc
    11641 tcatttgaga taatattata tcttcgctat caggttcaat tcctcctgta tccactaatg
    11701 taaaatattt atctaaccat tctacttcag caaatattct atctcttgta actccaggtg
    11761 tattttcaac tattgatatc ctttttcctg caaatttatt aaatattgta gacttaccaa
    11821 cgtttggtct cccaactaca gctacaactg gcctacttat actcatttta tttctccttc
    11881 catcttttat tttctatttt aaaattttat ccacaaaatc ttttccttca ttcaaacaag
    11941 ggataatttt tattctcata agttcttcta attgatttaa ttcaatatta tctaagaaaa
    12001 tttcttcatc tgcttttagc atacttcttg ttatataaag agcttctcct aattctttat
    12061 cttcaagttg ttcttttaaa tccttagctg ttaaaagacc tgatacagtt attgtctctc
    12121 caaaaaactt gtttttgatt tcatatacat ttacttgaag atttttaaac ttgtccatca
    12181 tagcatctgc catactctgt ataaattcat atgcagaatg accagtagct attgatactt
    12241 tcttctctct ttttagaata ttctcaggca atatatttag atactcttca atctctgttt
    12301 ttaacttacg tatcatacct acaccatctt caaactgtaa aaaaccttca tattcttcat
    12361 atccaggcaa ttcactatta gatagtatat aaaattcatc tgataaaaat gcaaatcgag
    12421 tacctaattt ttcaagatat ttctgttgta tttgatgtat ttgctctata gttttacttg
    12481 cgctcttatc attaaatata tttaattcta ctagattttc tctatgcttt gtaatcccaa
    12541 ctggaactat cgcaacactg tttacatacg gataaagttg agctagttct tttattgttc
    12601 tatccaattc ctttccatca tttatacctg gacataaaac aatttgacag ttcatttcta
    12661 tatgagcatc tgccaatctc ttcattatac catataattt tcctgcaaat ttattgctta
    12721 tcattttttg tcttaactct ggattagttg tatgcacaga tatatttata ggacttattc
    12781 tatattttat aatattattt atatcttctt cactcatatt tgtaagtgtg acaaaatttc
    12841 cttgtaaaaa agataatctc gaatcatcat ctttaaaata aagagtttct ctcatacctt
    12901 ctggcaattg gtctataaaa caaaacatac acttatttct acagctttta gcttggtcaa
    12961 ttatcggatt tgtaaattca acacccaaat cttcatcata gtctttttct atctcgtata
    13021 tgtagacttc gccatctttt ttttgtattt ctacatctaa atattcatca cttagtaaga
    13081 atctatactc tattatatca tgtattggct gttcattcac agatataagt aaatctccta
    13141 cctctatacc catttcttct gcaatactat ctttataaac cttacttata atattattta
    13201 ctttttttac atttacttcc aatattttca ccactctttt gtattcatca atgcttatta
    13261 taatgtattt taatatgcaa tttatttatt tattatattt tatgatagca tttttaagca
    13321 tttcatgtca taataacaca ttttaattct aatagtcaat ataagtaaat agctataaaa
    13381 tagattagaa caaataatat tcaaatttaa gtttcttaaa aatttaaata ttatttgttc
    13441 ttaaaaaaat tttataaatt taatgtttta ctatgattaa cgtcccattt gtcatatcat
    13501 gaaccattcc acctacacac tttgacatca acaatgcctt attttgtaag tctttctcat
    13561 catttgcata aaatattgga caacctccac catttttcat attcttatca agtgtaacta
    13621 tagctagggt atattcattt aaacctatat ccattcccat cttatgcact tcctttcttt
    13681 cctattttat aattttttag tgataagttt tttcctttag agcttgaaag tattgggcat
    13741 gactttacag cttccattac tttttccaca ttcttatcta ctggtaaata agcaatcatt
    13801 atactttcat cctctttatt tcttctaggt aatggtacga atgaaggttc tccataatct
    13861 ccatataaac ctaaccttga atatatattg tatactattg cttgtctttg accggagtca
    13921 aataatattc ctgcattagc ataatcctta tttttaggaa ttatttgtat tcctacacct
    13981 ctattaatat atacttctct atcgcttttt agacctatat ttgttatacc ttttaaatct
    14041 cccaccttta gtatagattc gtccacaaaa ctaatttcag caggcattac atcagctatg
    14101 tctccaatac tttttctagt aagaagtttt tttaatataa aggctaacac taatccacaa
    14161 attgaactta ttaccaaact catcccttca cttattttcg tttctgcaag tattacataa
    14221 tacaatccta ttgttaaaaa agatgtaact atacacatat aatttcttac ttcataggtt
    14281 ctagctatct cttctatgaa tgcagctcct ctctttacaa gttgaacttc ctctaaattt
    14341 tgcaatgtat ttcttctatt tgctctcacc tgtctaaatt gttctgctgc tagagataaa
    14401 aatgttatgg atgtataaga acgatttata agagctggaa ccaataatgc tcctaatgaa
    14461 gaagcgacga atgctaatat aagttgagat agtaaaacat ttggttgcgt tggatactgt
    14521 ttttggtcta aattcaacat tataattcta gatgttatac caataataac agcaacaaaa
    14581 aatactctat ccattaaatc actcctaaaa tatttaattt gaaattttac atgtaaatct
    14641 acaaagtctt tctagaaaaa tcactctgct ttccttttga tgtttctatg ataggtgtac
    14701 ttttcactac atctatcatg acatctatat ctttgagtat tggcatatat ggtataacca
    14761 cagtactttt ttctaaattg gtcttagata tagcaacaat atcaacctca tctacatctc
    14821 tatctatccc catatgaata aatagattat gtattatagc ttgtctttgc cctatatcat
    14881 ttactattcc aaatgcacct aaatctcttg gtataacttc tatggccaga cattcatttc
    14941 tatacttttc tcttgtactt tctagaccta tattagttat tattacacca tttaccatta
    15001 aaataggtcc ttcaaaactt atttttgcag gaactatatc tgctatatct gctatactgt
    15061 ttcttcttaa aaatcttcta aaaatcaaac caacaatagc tcctgacaca atagctaaga
    15121 ttgtacaata aaaaaagcta aggtcatact ttcttgcaaa aacgatataa actattgaag
    15181 atactagtgc agaaaaaaga cttatataac ttctagattc gtacgtagat gctatttctt
    15241 caacgtaagc atctcctttt ggtactaatt cttcattatc gatattcttt agtgttattc
    15301 tttcttgttc cgcaaggcct tgaaactgtt gtattgctac tgcaaaaaat gtcaaggctg
    15361 caaactcctt atctataagt gcaggtaatg ctatagcacc taacgaagct gaaagcccag
    15421 atataattat ctgttctaaa taatcttgtg gtcttgatgg gtattgtttg tctgtaactc
    15481 ttaaaactaa tcctctacat aatattccta caactaatgc aactataaaa gagtgtctaa
    15541 ataaatttgc attcaataaa ctttcttcca ttttctcagc tccttctctt atatagtttg
    15601 tgcaaaaaac aaaaaaaatt cccttctatt taaggaaatt tttttgtaat attgtaacta
    15661 taaattcgct accaatgcca agttcacttt ttacttttat acatccattt agtgatttga
    15721 ctatatgctt tgttatagcc aatcctaaac ccgttcctcc tacatcccta cttcttgctt
    15781 tatctaccct ataaaatcgt tcaaatatgc gttctacatc ttcttttggt atccctacac
    15841 cattgtctat aactttaatt acgatttttt cttcatcttt taacactaca acttgtacaa
    15901 tcccattatc ttgggtatac tttatagcat tatcaactag gtttaagaac acttgcttta
    15961 tatagtcttt attggatagt atacttattg atttatcatc acatttatat aaaacttcta
    16021 tatttttttc actagctgaa tgttgagtta tttcatatac ctctttaaat acatcatata
    16081 ctacaacatt ttccataaga agagtatctt tattttctac aaatgataac aacaatatat
    16141 catcaatcaa cctttttaat ctatctgatt cgctttctat tatttctaag aatctatttc
    16201 tagtattcac atctatattt tcatttgact ttagtgtttc aacaaatcca cttatagatg
    16261 taagtggtgt tttaagttca tgacttacat ttgcaacaaa atcacttctc atattttcaa
    16321 gtttaacttt tttagtaata tcttctatat ttactatcga acctattatt acgttgttag
    16381 tattctgaag ataaactggg tctactttta tcttatatac aatatcatct ttagtagtaa
    16441 tattagcagt ttcattatct ttagaaccaa taaattgaag tatttgtttt aatatttctt
    16501 cttctttgat tacaacatta atattatgac cttcaactaa ttgatttggt tcactcttta
    16561 tcatttcttt tgcttcatca tttatcagaa gtatatttcc atttacatct atagctaaaa
    16621 ttccatgaga tatactcttt aatatagacc ttaactgtaa atgtttatac tgtacttctt
    16681 ctaaggtttt atccatattc tttatcatat gattaaaatt tctagctaat tcgccaagtt
    16741 ctcctttggc tgatatgtta agcctagcat gatattcatt attacttact ttttttgaga
    16801 cgtatataaa ctcttttaaa tatttcctta atgttattgt gtatcttaca gctaatataa
    16861 caatggctat ggacaacata acaataaaaa aatatatact atttaaatct tccacaagat
    16921 aacactccta aaatataacc tttttaatct attttgtatc ctacacctct tatagtctct
    16981 atatattttt ccgatttatc ttcatcttct attttttttc ttaaatatct tatatgaaca
    17041 tctactgttc tagtttctcc atagtattca tacccccata ttttatccaa aagataattt
    17101 cttgaaagta cttttccttt attttgaatt aataatttta acaattcaaa ttccttaaga
    17161 gttaactcta tcttttcaga gcctttggta acttcatgtt ttgataaatc tagttttaaa
    17221 ttacctgtag taagtatatt gttttcttca cctaagctag tcaaattata tctccttaaa
    17281 acagaactaa tcctagctaa caactctttt atactaaatg gcttagttat atagtcatca
    17341 gcacctattt caagcccttc aaccttgtca ttttccatat ttttagcagt aagcattata
    17401 acaggaatat tttttaagtc cttatcactt cttatttttc tcaaaacttc tattccactt
    17461 atatttggta acatccaatc taaaagtatt aaatctggtt taatttcctt agcctttata
    17521 aatccgtcaa atccatcata tgaataacta acttcgtaat ttgacacctc caaattgaat
    17581 tttaatagct caactatatg catttcatcg tctataacaa gcactttagt attcattaaa
    17641 aagctcctct ctattttatc tgtagtaccg ttcctattcg ttctgatgcc ttattatgtt
    17701 ttctataaga gtggaattta tctgctctac aactagtgca taaatttaaa tttattatat
    17761 tttctttttt aactccacta catctaagca tatactcatt aattttccat aaatctaaat
    17821 agtaacttcc ctcttttatt atatagaact tttcatcatt atttgtaaga attgtgttaa
    17881 atttttctac taaatcttca gacacttcat aacaacatgg tccaattgat ggtccaatta
    17941 tacatactaa atcttcagga actgttttat agcattcaga cattaatttt attgttttat
    18001 gacctatatt actaaaagtc cctctccaac ctgcatgagc cagtcctatg gctttatttt
    18061 tagcatctat aattgatata ggtacacagt ctgctgtaaa cagtaaaagt ggtacttttt
    18121 ccaagtttgt tataagtgca tctccatctc ttcttttccc tatagtatct ttattgacta
    18181 tattaactat atctgaatgt atttgagaat tactagttag attttcaaat gtcaaatcac
    18241 attctttaca tacttttaac atatcttctc tattttttgc atctatattc ttacatgtta
    18301 taactagatt tacagaattt aatttttcat caagttcttc acaattacca cttaaattaa
    18361 catactcttt aatatcttgt acatttttta tatttatata atctttcatc atttgtctcc
    18421 tttttctatc agtatacttt taagttcatt tacaaaagta tttatatctt taaattgtct
    18481 atacacagaa gcaaatctta cataggcaac ctcatctaac tctttcaatt tatccattac
    18541 catctcaccg atttttttgg tttcaatttc ttctataaaa catttattta tttcattttc
    18601 aatatgtaca acaatacttt caatctcgtc aatagaaaca ggtctttttt cacatgcttt
    18661 taacaatcca tattttatct tttctctatc aaaatattct ctactattat cctttttaat
    18721 gaccattaaa ggagttgttt ctattttctc atacgtagta aacctctttt tacatgattc
    18781 acactcacgt cttcttctga tagattttaa atctgtatgt ctagaatcta ttacctttga
    18841 ttctttataa ttacaataag gacattgcat ctatattcct cctttgttta actatatctc
    18901 aaactcatct aagcttaatt ctgaacctat atttactatt attgtatcac aacctatttt
    18961 aagtatatca ttccaaaata taacttcttc atcccctcct cttgaaaaaa aacttctact
    19021 tccatctcca aaaatggtaa atgagactac cttaccttcg tgaatatcca tgtctatgtc
    19081 tattataaac cccatccttt ttccattttt tacatttata atttcttttt ccattatatc
    19141 agaaactcta atcatattgt actcaccctt tctttaaaaa taaatatgta tcgaagtaaa
    19201 aaaaaatgac ctatataggt catttaaatt aaaataatgt ttacagtcca tggattactt
    19261 atacatattt tctcatattc tttaaagcat ttttttcaat tcttgatact tgtgcttgag
    19321 atataccgat ttcatcagca acttctatct gagttcttcc tttgtaaaac cttaaatcta
    19381 ataccaactt ttctctacta tttaatttct taatagcttc tttaagtgat atttcttgca
    19441 accaattttc atcagtatct tttttatctt gaacctgatc cataacgaat attgcatctc
    19501 cattgtcttg atatactggg tcaaacagag atattgggtc ttgtatggca tcaagtgcca
    19561 ttacaactga ttctacttct aattctaatt cctttgctat ttctgatact gtaggttctt
    19621 tagaatttgt tctaattaat ctttctctaa cttgtagtgc cttatatgct atatctttta
    19681 atgacctact tactctaatt gggttattgt ctcttagata ccttctaatt tctcctataa
    19741 tcataggaac agcataagtt gaaaacctta cattttggct taaatcaaag ttatctatcg
    19801 cttttataag accaatacaa cctatttgaa ataaatcgtc tatattttct cctctgttgt
    19861 taaacttttt tattacactc aagactaatc ttaaattccc tcttacaaac tgttgtctgg
    19921 cttcttcatc accatttttt atttgtaata aaagttcctt catttgctta tttttaagaa
    19981 ctggaagttc tgatgtatta acaccacata tttcaacctt attaacttgc atatattttc
    20041 agtcctctct caaaagtatt catctattga aattatttac atttccaatt tttttatact
    20101 ttttaagaag aattaattta gcattataca aattttttca tttctttttg caaccttgag
    20161 attattttct tttcaagtct agatatgtag gactgtgata ttccaagcat tccagcaact
    20221 tctttttgtg ttttttcaat acctttatca ataagaccaa atcttaattc cataatttgc
    20281 ttttctctgt cacttaatct gtcaagtgcc ataaccaaca aatctctatc tatttcttct
    20341 tcaattattt tgtatatttc atcattttct gtacccaata catcagataa taaaagttca
    20401 tttccatcta aatctatatt taaaggttca tcaaatgata cttctgtttt ctttttatta
    20461 ttttttctta agtacattaa tatttcattt tctatacatc tcgaagcata agttgccaat
    20521 tttatatttt tattcagttt aaaagtatta actgctttta tcaaacctat agttcctatt
    20581 gaaatcaaat cttctacatc tatacctgta ttttcaaatt ttctcgatat gtagactact
    20641 aatctaagat ttctttctat taaaattgac tttacacttt catctgtttc tagcttttgt
    20701 aaaagctcca tttcttcttc tggtttcaat ggaggaggaa gtatatttgc ccctcccata
    20761 tagtatattc cctttggctt tattattttt aatttaatac ctaacatagt aataaagctt
    20821 attattcttt ctttcaatcg taacattcct tgtccccctt aaattttcac ctaaaatcca
    20881 ggcaatatat ttggattcat tattgctcca tattctctat cattaaaatt tgaaatacca
    20941 agtattatat ttcctatctt ttgctcatct acttctatat agtcagcttt taagcctatt
    21001 attatgcttg tcttattact tccagcatgt ttataaggta ttattctaac tctacctgaa
    21061 gttttatcat ctaaacttcc tataatttct tgtgctttct tcatatctat atcttcataa
    21121 ttaatattta atagtttttc tggaataaat ccttctaaca cactagactt aactattatt
    21181 acatcacttt gacttattgg gtcttttaac aaattaccac tatctactaa agccttacag
    21241 caaaaacttt tttctagtaa gtttatattt atagtctttg taagctcctt aatgtactta
    21301 agcattttca aatctttata aatgtatttt aataattcac aactcacata agtacatgca
    21361 attaagaaag atatttttaa gtgacttatt cctgtaaaat aaattataaa ataagtgctt
    21421 ccagaaataa aaatgtttac tagataaaaa actaacgcta catgaacata atcttttttg
    21481 ctcttacttc taaatgaaat taaagttatt atactcatga ttattatttt aaatggtaca
    21541 gtaaatagta tattcattga tggatacaaa taagcaacag aataggcacc tcctaaacta
    21601 gcccccaata acttattttt tttaggatta tatcttttag taagaataga agtacaactt
    21661 ataataatat aatttattac taggttttct ataacatagt actcaatata caccatgtat
    21721 ccccccttaa aacctttaaa catattataa gatagtatgt acaaaatttt atgtcacttt
    21781 tgatggtcga atccaaaaca aattctattt aaaaagaaca atgatatatg tcttatactt
    21841 tatgtcgtca aaagatattt ttttaatacc aaacaaatag acttttttgt agaatccaat
    21901 atatctaggt agaagttatt cgctctactt ttggtatatt tacaaaaaaa gactacataa
    21961 tttaataata tatcaagtaa atcttttact tatataaaat caaattatat agtctgtaaa
    22021 ttcaaatata aattattgtg ctagtaatcc atttgcatat tttgcagatt catttagtgc
    22081 ttgttctgga gttatgtctc cagctatcat catttgaagt tgtttccata aatattcata
    22141 tatctctact ccatgaggtc caactgtcaa tggtctatac atatgtttat ctcttgtcac
    22201 catttcttca aatcttgggt ctccttggta tttttcacct ttagcaactg gagctctagg
    22261 tatttctttg tggaaagctt ccattgattc tttgcttagc atatactcaa gaagtttaaa
    22321 tccaagttct ttatttttac atgctgacat taatgttaaa tcatctactg aagcaaaact
    22381 tccaactgtc ttatcttcta atgatgttac atatccccag tttaaatccg ggaatgattt
    22441 atcaaaagta cttgtagcag cagaggatag cattatagta aatgcagctt ttcctggtcc
    22501 aaatacactt tcaatcattt cattactatc ttttgataaa gcatcttctg gaatatactt
    22561 tttcatatca tttataaagt ttgcagcttt caagccttct gcattattaa atttaactga
    22621 ttttaaatca tcattatata tatctccacc agcttgccat aaatacggat accagttcca
    22681 gtttaagctt ccaaatactt tagaacccca accttgtgca agaccccact ggtcgatttt
    22741 tccatctcca tcagtatctt ttgttgcttt ttcacagatt cttttaaaat catcccatgt
    22801 ttttggaggt ttttctccta atttttctag tatatcttta ttgtagtaca atacgcctgg
    22861 attagcagct tctataggta aaccataaat accacccatc atttttgcat catctaagta
    22921 tagataatta tctgaagttc ctgatttttc taaataaggt gttaaatctt ctaccgcacc
    22981 catttctata aattgaggaa acatctctgc atacatgtat cctatatctg gaccttcacc
    23041 tgcacttatt gctgttgcat atttttctgc gtagttatcc catggtacta tctgaaattc
    23101 aatttcacag ttattttctt tttcaaattt ttcaaatatc ggcttccatg catctgcatc
    23161 atgatctgtt aatggtgcag accatacaac taatttttct ttaccctctt tgcctttaga
    23221 atcttctttt tttgaacatc ctgcaagaat tgatactgat agaatcccta ccataactaa
    23281 agaaagaacc ttttttagtt taatcatgct taatcccctt tcagacttta atttgtcttt
    23341 ttcctcaaat gtttacattt aattcagatt taatattaac aaataagatt actcttgtct
    23401 aatcataaaa aactatacta actcctataa ctatattttt tttctatacc tattagattt
    23461 aattcatact aaaaacttac tttttaaatt ttatcaatat ttaaaaatat ttttaagtct
    23521 agccacaaac taactatcta aattgaacaa aataaaaaga agtctattga cttctttata
    23581 agcttacata ttatcttctt cttcttagga atgtaggtat ctccatgctc tcatcatcat
    23641 cttcttcaat tatacttgcc tttttaggag gctctatttt ttcctcagca attacttctt
    23701 cttcaatttc ttttacagct tgttttactg ttgtatttaa tgaagaacgt atgcttgatt
    23761 taggtttagt atctaaatct aaggcaccat tttgtaatcc ttcaaatcct gtcgcgatta
    23821 ctgtaatcat tatttcatca cctaaatctt cttttataga agctccaaat ataacatttg
    23881 cttctgggtc acaggattcc ataactaaag ttgatgcctc attaacttca aataatccta
    23941 agttaggacc acctgtaaca ttaagaagta ctcctttagc tccttgtatt gatgtttcta
    24001 gaagtggaga ttgaatagct tgtcttgcag catcaattgc tctagtttca ccactagcac
    24061 tacctatacc catatgagca agtcccttgt ctttcattat agtagtaaca tctgcaaagt
    24121 ccaagtttat taacccttca actgctataa gatctgaaat tgattgtata ccttgtttta
    24181 atacatcatc tgcaactgca aaagcatcta acattgatgt atttttttgt actatctgta
    24241 aaagtctatc atttggtatc gttataagag tatctacttt tgatttaagt tctgctattc
    24301 caccttcagc gttcttcatt cttatcttac cttcaaatgc aaaaggtttg gtaactacac
    24361 ctactgtaag tatccccatt tcttttgcca agcctgcaac cactggagca gctcctgtac
    24421 cagtaccacc gcccattccg gctgttacaa agaccatatc agctccttga agtaacttta
    24481 ctatttcatc tttactctcc tcagcagctc ttttccctac ttctggattt gctcctgctc
    24541 caagtcctct agttaatttt tctcctattt gaactttata ttcagctttt gatgtatata
    24601 aagcttgttt atctgtattt actgatataa attcaacgcc ttttagttga gcttctacca
    24661 ttctattgac agcattgttt ccaccgccac ctacacctat tactttaatt tgtgcacatt
    24721 cttctaattc tacgtcaaag tttagcatca taaaccccct tctctcatga ttcaaagtta
    24781 tcgtatgtat taattatatc attttcttct tttattttgt taacctttaa gtaacatatt
    24841 ccacaaaaac gtaaattttc ctttttaaat ttcttactta tattgtcaaa tattactctt
    24901 taagtataaa ataatttacg tatatattaa atgctcttta atttttacgt tttttgttca
    24961 taatattact aataatatat cgtctaatta tagataagtt attaaacaat ctcataccaa
    25021 aaactaatac agcaacatag taaagagaaa ctcctaactt ttctcctata taagtcaata
    25081 atatagccaa tatagcatta cctatgaaac cagtaataaa aattacatta tcatagttat
    25141 cttcaaaatt ggattttatc gctccaaaaa tagaatccat tattgcaaga atagctactg
    25201 acatatatat ggaataatcc atagaatatg taaatggaat atagtaacct actactacac
    25261 caaatgctaa tcctcctaaa acccataaca taaatcttca cctctttatt ttactttgaa
    25321 acacaactac attacaatcc tttttattaa ttttttttac tttttcttta tttttttgta
    25381 tttttcgttt tattttgcaa ataaattcac tttatttcca ttattttcct gaacttttat
    25441 attaattcca tatatatcct taagagattt agcatatgat tctggagagt ttatagctgc
    25501 actcaataaa tctatatctc ctatagcttt tattataaat ggttgtccat atgtagtatc
    25561 atttactgta atagtagctc ctgaacattt tatcttactt gttgctagta ctctttctcc
    25621 atttatagaa attgctcttg ctccagcctt ttttaaatca tttaaaaccc tcaaaatatc
    25681 tatatcatgt ataatcaaat cgtttggatt ctgtccgtct tttaactctc tctcactatc
    25741 cctcatagta atagttatgc ctggccctgt aacagttgaa taaccactta actctttaac
    25801 ttcttcaagc tctttttgca taagtgtttg gatagattca tttccattct tttttgcttc
    25861 tttatattca ttcaaagttt ttttgttctt tttaagagtt tcttttaaat tttttatttc
    25921 tttttttgta ttttctacct cactttcaat actttcagtt tgacctaatg ttatgtatac
    25981 tctatttggg tctagtgatt ttatataagt tgatatgaaa acgcctaata tgaatgctcc
    26041 taatataact attttctttt tcatactatt atttcccctc tgctttgttt atatcactat
    26101 gaccatttat ttctatattg tcttctttgg tcacttttac tttggcatta taatatgttt
    26161 ctatttccca gacaatacca tactttatat taagtgctga agccaatgta tcagaatcac
    26221 caattgcttt tattataatt ggttctttta tgacagtgtc attcatataa agcttgtctt
    26281 cttttaaata catatatgta ttagaaacta ttctctggtc gtttatagat atggcacttg
    26341 cttgtgctga atttaattta tttatcattg acaataataa atcataatta tatagtatac
    26401 tatcattttt atcagagttt cctaagtctt ttgtagaatt tatctcaatt tttatgcctg
    26461 ttccttcaac atctgtatat ccagctaatg tttcatattt ttctatttct gacttaagta
    26521 tgtcttgttc tccttcattg tttttgcctc tataagtctc tatagctttc ttcacactat
    26581 taacttctga ttgtagattc tctttttctt tttttaatga tttaagttct tctgtaagtt
    26641 gctctcctct tttaaaagtt gtcatccctc tattttctat attaataatt ttaagttgta
    26701 aactaacaag aacacccaat acaatacttc ctatgattat acttttattt ataaatcttt
    26761 ttttcaatat atcacttcct tacaattgtc tatccttctg gactatacac tgccaacttt
    26821 ccatagttaa gatttatagt ccctccatta gtatttttat tttgcaggtc aatcagaatt
    26881 ttacttaccc tagatatatt ataatctaag ttatcatcat tagaaagtaa gatttttata
    26941 ttacttcttg taagcatttc tatattgctt tcttttttta agtttacata atttattttt
    27001 ctataaattc cttcttcttt taaataattt aaagttttaa atacattctc cttagtttta
    27061 taatttttaa attttataga tttattatca tcaatgctat aatctacatc tactatcaag
    27121 tcttttttac tttcattaga acctcttagt tcttccaata aatttccttt tttatctata
    27181 taacaataat tatcttcatc ttttaatact gcaaatattt ctttttcttt taaacttata
    27241 attatcttat tgggaagttt tctttttatt tccacatttt ctatatatgg attttttata
    27301 agtttatttt tcatatcttt aaaattgtat gcaaaaatat tttcatttag atttacattt
    27361 agttctttca ttatatttga tttggtcacc ctcttatttc caattacatc tattttcttt
    27421 acatcaaata aatcactttt tacaattata catatacaaa aagataacat aagtataaaa
    27481 actaaaacta tcatgacatt attcgtattt aactttcttc tttttttcaa atataatcaa
    27541 cccctttggt taataaatac acctttagag cttgtttttc ctacaaaaaa attataatat
    27601 ttaaagtcaa atttttgcat tttattacat aacatccaaa taaggtatta aattttataa
    27661 ataaatcaat atttcatcaa aataaacata gcatactaca tactatttat atatttaaat
    27721 ctgtatacat acaaataaac ccctaattta taataattta gaaaatctaa tatattataa
    27781 attaggggta aatatttact tatcttttct ttattcctat taccttagct tgaccttcta
    27841 tacttggagt cgtttctttt tttatttctt ttacttcctt aataactttt tctttttttg
    27901 tttttttaga agctgatttt tgtgttgaat tgtatacttt cattatctca tcatatataa
    27961 ggtctatggc ttcaggctta cctatagttt tacttgcatt tgccatatca accaaaagtt
    28021 ctctatctcc taaaagttta aatactgctg tatttaggct ctctggagtt agattttttt
    28081 ctaaaatagc aattcctgcc ccttgttttt ctatactctt ggcattatac tcttgatgat
    28141 tttcagcagt ataagcttta ggtattatta tagatggctt tccaagagcc gttatctcag
    28201 ctaatgaaat tgctcctgcg ctacctataa ccaaatcact tgctgcaagt gcatttgcca
    28261 tatcttctaa gtaaggcaca actttttggt atggtttaag atttatatcg ctaatacttc
    28321 ccataaattc atcataatag cttttgcctg tagcaaatat aaaagctata tcttcattta
    28381 ccatattctt tattacaagt ctcattgcat catttatttt tcttgaacct ccactaccac
    28441 catagcaaag taccattctt ttttcgtcac ttattgatag attctttctt gcaatatttt
    28501 ttcttgataa taaaatttct tttctaactg gatttcctgt aaaaactaat ttatcttctg
    28561 ctgcctctgg aaatctttta tgcgaatctt caaaacttgt aagtaccttt gtaactgttt
    28621 tagataaaat cttattagtt acaccaggaa aagaattttg ctcatgtatt atggctggta
    28681 ttttccccat agatgcatta aataaaacag gtccactaac atatccacca gttcctataa
    28741 ctatatctgg tttaaatttc ttaacaatct ttcttgattg ctccaaacct ttaaaaagct
    28801 taaaaactct ttttacatta tcgaaatcta tttttcgctt aaaaccttga actgttacag
    28861 tctttaattc aaatccatac ttaggaacta tttctgactc tattcccttt tccgtcccaa
    28921 caaaaattat ctcagcgtct ggatgctcat ctcttatttt gtttgcaata gctatagctg
    28981 gatacacgtg ccctccagtt ccaccgcctg ataataaaac tttcatcaaa tcatcatctc
    29041 ctgttaatta attttgacat gctttgagat gtttaacact attcctacag ctcccataaa
    29101 gatggtgagt gaagttcctc cataacttat aaatggtagt gctacacctg tagctggcat
    29161 tgatgatgtc gcaactgcta tatttaaagc tgcttgtatt ccaatttgtg cacctatacc
    29221 tataacaacc atacaagcaa atacattaga agtcttcaaa gctattctta cacatctgta
    29281 gactaaaact acaaatagca taataactat tatacaacca atcaatccta actcttctcc
    29341 tattatagca aatataaagt cattttgtgg ctctggtata taaaaatact tttgtttact
    29401 ctttcctaag cctagaccaa acaatccacc tgaacctagt gcatatagac cttgtattac
    29461 ctgatacccc ttaccaagag ggtcttgaaa agggtctaaa aatgatgtaa cacgactaag
    29521 tctatagggt tcagcaatta ctaatgcagc aaataaagca gccccactcc ctatcatagc
    29581 aaatacaatt ttcatatcca ttccagcaac aaatatcatt acaaaagtaa ctagaattac
    29641 agtacctgct gttgacaaat ttggctgaag tattatcaac gcaaaaaata tccctggaac
    29701 tacgagaagt ggtacaacac cttttgtcaa agattttatt ttatcataat ttttttcaat
    29761 taattttgca gttaatatta ttgtagcaaa ctttgcgatt tctgcaggtt gaaatgttaa
    29821 agctcctatt cccaaccatc tttttgctcc gtttgcttct atccctaaag gggtcaaaac
    29881 taacaataat aatactactg ctatagctcc aattgctgta gcatttttct tccaaaaact
    29941 ataatctatt cttgatgtaa taatcataac tataaatcca agtacagcat atattacatt
    30001 cttttttaga aaatagtacg catcattgtg tttaaatgaa gattgtataa aacttgcact
    30061 aaacaccata actattccta caaatactaa aagcatagta gtgtaaaaca ctactccatc
    30121 aaattcagtc ttcatcctta tgtcaatttg ttttttcaaa ttttctttag gcatccaact
    30181 aatctacctc cattcttcca tttaagtaag tttagaggta agagattatt ttaaattgtt
    30241 tacattatct ttgaagtctt ttcctcttac ttcaaaactt tcatacatat cccaacttgc
    30301 acaagctggt gaaagaagca ctatatctcc actttttgaa atttcataag aagtcttaac
    30361 tgcttcttcc atatctttta ctatatgtat gtcattaaat cctttatttt tagcacaatt
    30421 ttctatattt gatgcagttt ctcctaataa gaccaatgat ttaacatatg actttgcagt
    30481 ttcaagaagt tcatcaaaat tacttccctt atccatcccc cctgctataa gtattatagg
    30541 tctatcataa gactgtatag cttttatagt ggaatctgga ttagttccct ttgaatcatt
    30601 tacatatatt acattgtcta aatttcttac aaactcttgt ctgtgttcca ctcctttaaa
    30661 tgtcataagt acatccttta taacttctaa atcaattttg cagacatatg ctattgctat
    30721 agctgccata caattttcta agttatgacc tccaggtaaa cttacatcat ctttatttag
    30781 aaatttgatt ttatcatcta tatctattat tatgtcatta ttttctaaat atactcctcc
    30841 atttactttt ttagttcttg aaaagtaaat tactttggca ttgcatttat cagctaaaga
    30901 ttttactatc tcatcatcat agtttaatac acagaaatcc tcaacagttt ggttcataaa
    30961 tatatttgcc tttgcttcta tgtatttttc catagtatgg tgtctattta agtggtcctc
    31021 tgtaatattt aatattgcgc ttactttagg tctaaattca tctatactct caagctgaaa
    31081 actgcttagt tcagttacta acacagactc ttcacttgaa gtttctatag tatctattac
    31141 aggatttcct atattaccaa ctacatatgt atctcgtttt gctcttgaaa aaatttctcc
    31201 taccaaacta gttgtagttg tctttccatt tgtacctgta atccctataa aaattggatt
    31261 attcgatagt ttaaaagcta attctacctc accaattata tacttgcctg aattttttaa
    31321 tttcaatatg aatggtaggt ctagtggtac acctggagac actacaacca tatctatatc
    31381 atctacatct tctgggtgat gtcctaatat gtattttatg tcatttatag atttcaattc
    31441 atcaagtata tttctcaatt tattttcatc ttttatatca tttacgatta tacttgcacc
    31501 caatttatct aaatgtttaa ttgtagatat accagttttt gcaagtccta ctaataaaac
    31561 tttttttcct tttaagtcca tttttcattc cccctagccc taaaatactg ctattatact
    31621 tatccaagct aaaacaactg ttataatcca aaaaataaat acaactcttg tttctggcca
    31681 accacactgt tcaaagtggt ggtgtattgg agccatctta aagaatctct ttcttgttgc
    31741 cttaaaatat ccaacttgaa tcaaaactga tagagcctcc gcaaaataaa ttcctccaat
    31801 tataggtatt ataagcactg agttagttag aactgaaaat gctacaactg cacctcctaa
    31861 tgccattgaa cctgtgtcgc ccataaacac tctagccgga tatgaattaa atcctaagaa
    31921 acctaaacat gctccaacag ttgctgctgc taaaactgcg acttctgtat ttccagcaat
    31981 agaacttgca aatagcataa agaatacaga aactattaat gttactcctg atgctaatcc
    32041 atctaatcca tcagtcaagt ttacagcatt tactattgct acgattataa acatcattat
    32101 tggtatatat aatattccaa catttatcac aaaatctgta aatggtatca taagttgtga
    32161 agcacttgat gatgatgtat actgataaaa agcaacataa aaagataatg caacttgaag
    32221 gattattttt tgatatgctt ttagtccaag tgatcttttt agctttattt ttataaaatc
    32281 atctaaaaag ccaataaaac caaaacctgc aatacatata agacctactg ccatatcatg
    32341 actaactttt actcttgtaa gtccagttat tagaattgca acaatcatta taattccacc
    32401 catagtaggt gttccgtttt tagctagatg tgtttggggt ccatcatctc taactgtctg
    32461 accaaattta aattttctaa gcattggtat aaatattggt cctattataa ttactattaa
    32521 aaacgcaatc aatgcggtgt acgtaagctc tgttattcct aacatcataa aactcctctc
    32581 ccttgtcaat taactcatta gtttaagctt atttatttag atattcgact attttttcta
    32641 atctcatgcc tcttgagcct tttactaaaa tagtgtctcc tgtttttact aattcattta
    32701 acttgttaaa cacatcttct ctattctcaa agtgatatat attggctgaa ttgaatccta
    32761 attgttttgc ttcttctcca ataaacactg aattttcacc tatagttatt ataatatcag
    32821 tattattcat agatgatttt ccaactaatc tatgaccata ctctgaaatt tcacccattt
    32881 ctagtatatc tccaagtatc gctacccttc tacctttata tcttccaagt atctttaaag
    32941 cagcatccat agaatctgga ctagcattat atgaatcatt aattattgtt aatttttcat
    33001 tttttattat gtctagtctc atttttgtcc ctttaaaatt ttttaaacct ttttttatat
    33061 aatctaaaga aatatttaga cacaaaccaa ctaatatagc agacattgca ttatatatat
    33121 tatgttctcc tattgttggt ataaatattt cctctttttt cccatttatt acacatataa
    33181 atgttaaact atcctcttcc atagtataac tttcacaata aacatcattg tttttattaa
    33241 agccaaatgt ttttaactta tatgcatgtt ctttttcttt taatgtagat aaaaacttat
    33301 catctccatt tacaattaaa gtatttgttt catcaaagtt tgaagtaatc tccatctttg
    33361 ctttcaaaat accctcttgt gaacctagtt tttctacatg tgataatcct atattcgata
    33421 tgactgcaat tttaggattt actatatcca ctaaatattt tatttcattg aatccagaca
    33481 tacccatctc tattacagca cactcatgtt ctttatttag attaaataaa gtcaatggaa
    33541 ctccaaaatg attatttaag tttttttcat tttttagtat atttaacttt gcagatatgg
    33601 cagagtaaat catatctcta gtagtagttt ttcccacact acctgtaaca cctataaatg
    33661 gaatatcaaa tttttcttta tagtattttg aaatatctcc tagagccaaa gatgtatctt
    33721 ttacctctat taaatttata tccgaacttt ctaattttat tccattactt tcatttttta
    33781 taaaagtttt acatccacta tcatatgcag acttcataaa tgtatgccca tctaaatttt
    33841 ctccaactat ggctacaaat gcattttggg catttgcctc cctgctatct ataactatat
    33901 cacttacaca gtcattataa tctccatata ttaacttccc attagttgca agtactaact
    33961 cttttattgt taagcactcc attattaaac tcctccttta aaaccttagc tatattctct
    34021 tagcaacaaa aggcaatgta taccgttata tatacattgc ctacgataac tcttaacttt
    34081 ataattatat actatatttc tgtttttttg aagatgttta tgggtatatg ttaattatct
    34141 gttacttttt agttttcaaa atatagggtt atacttgagt cttcattaac ttttactcca
    34201 ggttttggga atatatcctt tacctttgta tcttctggaa gttctatatc tgcatctaag
    34261 tctggtttta acttcgcatc ctccaatgcc tttacagcat ctcctatttt tagatttctt
    34321 acatctggca ctttaacttg cttcttttca tactcagctt tctcttcttc tttatatact
    34381 ggtttaactc ccaaatattt taaagagtca ttcattattt ctttcactat tggtcctgct
    34441 gtagtactac caaatgcact tactcctgtt ggttcgtcaa caatagcaag aactactatt
    34501 tgcgggtcat cacaaggtgc tattccaaca aatgaacata tatattttcc tggagcatac
    34561 ttaccatcta taactttttg agctgtacct gttttaccac caagtctata acctggtata
    34621 tatgctatct ttcctccacc ttcagttaca actgattctg caatttctaa cattttttta
    34681 gatgtttctt tagatataac acttcttact ttttttggtt ttactgtttc agttatattt
    34741 cctttattgt cagtataaga ttttaccact cttggttgca ttaaatctcc accattagct
    34801 attgatgata tagctgttat aagttgtatt ggagttactg atatagattg accaaatgat
    34861 attgtagcca attcaactgg tcctacattt ttttcgttat acagtattcc cttagcttct
    34921 cctggtaaat ctatacctgt cttatccata agaccaaatg cttctatata atcatacatt
    34981 tttccaacac ctaatctgct tcctaactca acaaatactg ggttgcaaga gttttgtact
    35041 gcttgtttaa attcttgtgt tccatgaggt ctgtaatgtc tccaacattt aatctttctt
    35101 cctccaacag ttacactacc tgtacatgtg aatttttctc catctttaat tactccttct
    35161 tcaagagcac tagaagatgt aataagctta aatgtagaac ctggttcata tgtatcactt
    35221 actgctggat ttctccacat ttgataatag ccttttattt tatctttatc attatatttt
    35281 tcaagttctt cttgataata tggatatatt ggcgttcttg agtcattagg gtcataatct
    35341 ggttttgatg ctaaagcaag tatatcacct gttttagggt tcatagctat tgcagtaacc
    35401 ttttttgcat tatttaactc ataagctttc tgtactgctt tttcagtata gtgttgaatt
    35461 acttcatcta tagacaacac aagaccatta ccttgtacag gctcataata tttttccatt
    35521 ccttgtggta tttctcttcc tgaagcatca gtacttacta taagttttcc aggctttcct
    35581 tttaactttt tatcatattg catttctaca ccagatatac ctgttgcatc tgaagaagta
    35641 tgtcctaaca catatggtgc aaaattccca tatgggtaat atctttgatt atcttctgcc
    35701 acccatattc cacttaattt agcatctctt atttgacttg ccttatcatc atctatccat
    35761 ctttttactt ttacaagagc catatttttt ttgcttatta aagcgtaaat atctttataa
    35821 tcttcatcca aaatctcagc taccttttcg gctgcttctt ttttatcttc tacttctaca
    35881 ggtttacacc aaacagtata cttagttaca cttactgcta actctttcat atttctatca
    35941 tatatagttc ctcttttggg ttctattggt atatctcttg tttgttgttc tagtgctttt
    36001 gtactcaacc aatttccctt cataagttgt agatacccag tcctaataac aaggcaaaaa
    36061 aacaatgcac atgctagaat aagaacgagt accagccttt tcttacttat cctctttact
    36121 tttctcaaat ctattccccc tagttatcca catctatata ctttatttgt ccatcttttg
    36181 gatagtccat attgagcaat tccttagcct ttagctcaat ttcttttatt gatgtttttt
    36241 cagtttcttt tgcctttagt tcctctaata ctatctcttt ttttcttaaa tctttttgta
    36301 aataatagat atcgtacttc atttccgaga tttttgaata accacataga ttcaatatta
    36361 ttactgaaaa agttgcaatc agtaaaatgc atttagctcc tatttttttc ttatttctct
    36421 ttttataatt attctttttt ttatttttat attcatttag attatgtatt ttataatttt
    36481 ttttcaaatt ctcaccccga tagtatatag tttaaatttt cctctatact atatttgtta
    36541 ttaatcatat ttcttcctct aaaatttcat cgctaaatta atacactatt acacaatcta
    36601 attgtatttt tttctataca caacaaaaac ctataaattc acttatactt ttatatgaat
    36661 ctataggtta gatattaatt tctatttatt tttatcactt ctagtatttt tagataattt
    36721 cttccataaa tataatatgt aactagctat ctactctctg attcctaagt tctccattat
    36781 attacttaat accatctata tctatatttt tatatctaaa ttttcattat atatctcaat
    36841 aacaaagaac atttcttata gtgttaattg ttttttaatt gctttaccag tgcaacaaaa
    36901 tatataatac tttttaatta attataataa tcttatatat aagattattc tttagcctta
    36961 taactactta tattttttct gctactctta gcttagcact tcttgaacgt ggatttactt
    37021 ctatttcttc ctcactaggt aatataggtt ttctagttat tattttcacc tcagattctt
    37081 tatcacattg gcatataggt aaatgctgtg gacatataca atctgatgct aaatgcttaa
    37141 atgcattttt cactattcta tcttctaatg aatggaatgt tattatacat attcttccac
    37201 cttcattcat tatagaagaa gcatcattta tcatctttgt aattactcca agttcattat
    37261 ttacttctat tcgtattgcc tgaaaagttc ttttagctgg gtgaggtcca tctattctag
    37321 ctttcttggg gatagctttt ttaattacat ctactaattc tcctgtagtt tctattggtt
    37381 tgtttgctct ttcttcaact ataaatttag ctatacgctt agcccagtta tcttcaccat
    37441 aatcttttat tatcttagtt aattcatctt ctgtataagt atttacaaca tcatatgcag
    37501 aaaactcaca cctaacatcc attctcatat caagtggtgc atcttgcata taagaaaatc
    37561 ctctatcagc ttcatcaagt tgatgagatg aaactcctaa atcagctaat acaccatcaa
    37621 ttttgtaaac tcctattttt tctaattcct cttttatatt ttcaaaattg ctgtgaacaa
    37681 acttcactct actttcatat tcactcaatc tctcttttgc tgtgcttata gcatttttat
    37741 cttggtcaaa ccctataaat aatcccttat ctgacagttt ttttactatt tctttagaat
    37801 gtcctgctcc tcccatagta cagtcaacat acacgccatc tggctttata tttaaattct
    37861 ctatacactc atttaaaaga actgatacat gatgaaattc catagttacc tcccttaaat
    37921 tcacttttta aactattctt cactaatatt atttttattt ttctttgata aataaacatg
    37981 tgcaattatg ccaccaataa ctccaattag acttataact tgtgccattc taagtggtcc
    38041 taacattaaa ctatctgttc ttaatccctc tataaaaaat cttcctattg aatataaagt
    38101 tatataagta actataactt gaccttcata ttttttattt tttctaaata gtaataaaac
    38161 tataaatatt ccaaaatccc atatagactc atataaaaaa gttggatgta cctttactcc
    38221 atcaaccatt attccccaag gtaaattggt agcacctcca tgtgcttctc cattaataaa
    38281 atttccccat cttccaatag cttgtgctaa aggcattcca agtataactg tatcagccat
    38341 ttttaagaag ttaatatttt taatcttagt gtatatataa ccagctaata ttccaccaat
    38401 taaccctcca tgtatagcaa ggccaccacc tctaaaatta aaaatttgag acatattttg
    38461 agcatagtaa ctccaattaa atacaacata atagattctt gcacagatta gtccaactgg
    38521 aattgctatt atagctatat ttaatacatc atcttcttta attcccactc tttttgcttc
    38581 ttttattgct attaaagttc ctaaaatcat tccacatgcc ataagtattc cataccacat
    38641 gatgtctatg ccaaacagtg taaatgctac tctatccata acgtcacctc tttgtattaa
    38701 ttgaaaatat ttccaaagca atatgatata attacaatta attgtaatta tactaaatta
    38761 tgataacaca ttaatgttaa ttctacaaaa aatattaaaa tttattctac aactccctac
    38821 actatattat atctaattac tataaaattt tttaaactga atctctcatg actaaagtta
    38881 caagtgtaca tagatatttt ttaatcaaaa agattgatgc atatatacat caacctcttc
    38941 tatttcttat ctatagctct taaattttta cctcaattta tataaatata ttttataaat
    39001 ttgttttacc aaaataaaca tttaaaaaca taaactaata cttaattagt tattcttatt
    39061 atgattaagt ttctatttag gctctacaat agaaataaca caatactctt ctttaaaatg
    39121 ctcttttaat ctttcttcaa cttcctcaaa agtaatatct ttaataatat ctaaataatc
    39181 caatagattt atatccttaa aaacataaga tataaaacta ttacctataa agtttataga
    39241 atcaaagcac ttaataaatg accctatttt tttcttttta gttctctcaa actcttcttt
    39301 tgataatcct tctttttttg atttttctat ataatcaaga attatttctt ttactttttt
    39361 aggctcttta gaatctccag ctattatgct aaaagcataa tccacttgag acgaaaatcc
    39421 agctccaaaa ttttcattta ttaaaccttg catatacaaa tcttcataaa gcttacttcc
    39481 ttttttaaat aacatcccta caagtatatc agttacaatc tctttacgta aaagttcttt
    39541 cccttttaaa ccaacattac tatctttaaa acctatgttg aacataggca tagatatagg
    39601 gaatttttct ataacctctt tttcttttac accttctggt tcttctggat aaaatctttc
    39661 tatactctta gagagtttgt ctactttgta attgtttgac tttttagtta catctataac
    39721 tttttctaca tctaagtcac caacaacaaa taaagccata tttcctggat tatagaaagt
    39781 attataacat ttatatagct cttccttagt tatcttatat atactatcaa cagtacctgc
    39841 tatatcaatt ctagcaggat aatttacata cattgccttc aagcaattaa agtatacatt
    39901 ccaatcaggg tcatcattgt acatttttat ctcttgtgct attatacctt tttccttttc
    39961 aacattttca tctgtaaaat aaggtgtttg aacatagtca attagatgtt ctaaactctc
    40021 ataaaaattt tcagtagcag aaaataagta ggctgtcatt gtaaaattag taaatgcatt
    40081 tgcatttact cctaattttg aaaatttatc aaatgcatct cctccatcag gttgctcaaa
    40141 catcttatgc tctagaaaat gtgcaatacc ttcattcact ctaattttct tatcttctcc
    40201 aattggtaca aattctaagt catttgaacc ataattagta gccaaaatag catacttttt
    40261 cataaaaccc cttttaggca taaaatatac atctaatcca ttttgcaatt tctcataata
    40321 aacttcttct ttcaatatat cattaactat tttttccata gacatctcct ccattaattt
    40381 ctcaagaagt atacagtatc aagctctata ttttttatag cttcaactat atcttttttt
    40441 gtaacctttt ctatactaga tattatatct tgtacttcag aatttgtctt tgccatagat
    40501 tgagagaaaa caaaatcaga cataccacct atattatcag ttatagattt catagaatta
    40561 actaaagcaa gtttactgtt ttctaattct tcatcagata tatcacctgc ttttacactt
    40621 tctacttgtt tttttatcaa ttctacagct ttatcataat ctttagtttc tataccagat
    40681 gatataaaca tgatactttt atacttctct attgaagaga atatatagta acataaactt
    40741 tctttttctc ttacattaac aaataattta gagtgtggac caccacctaa gacattgctc
    40801 ccaactacta aagcataata tttatctatg tctgcataat ccacatttgc tctataaccc
    40861 ataactaact taccttgagt tatttccatt tgttcatcta taacttttac ctcatccaca
    40921 ttttttataa aatctgctct tagtatattt ataatttctt ctctttcaaa ttttagattt
    40981 ttacttatta tatctacaac tttatcttca tcaaaattac cttctacaac tatatctata
    41041 ggtgatgttt taagtatgtt tttataatgt tcatataact ctcttgaagt tatactatct
    41101 atttcatctt cataaccaaa ttcacttaca ctatatctct ctcctttaca catagcctca
    41161 atacatttat cttgcgcata ttccttttta tcatttatta ttgattgtat cttttctctt
    41221 aaattctctt tttcaatatt taaatattct tctttaaacc caccatctac aacaagcgta
    41281 ttatttatta cttcattaaa aaattctact acttcttcaa atatactctc atctaaatac
    41341 ttttcactta tgttaattac tttaaaactc aatacttgac gttctccacg ttttacagca
    41401 tcagctccca tagatgaacc atataaatca tctaatttat tggatattgc tctagcacta
    41461 ggatatttag cgcttccact tgctattatt gatggtatta gagcattttt tgtagtttct
    41521 ttttcatcca ataatctctg aacatataaa cttataagat tcgatttaaa cttttctgtt
    41581 tttatcaaag taagattaat attattacct aaatttatta tttttttagt attaaccata
    41641 tgtacctcct atttttattt aaacatcaat tttaaaattg aaatttattt attttttaat
    41701 tacatatact cacatataaa aaccttctat ttaattatat cctttttatt attttctaaa
    41761 agcaatattt ttatttaaat taaatacaaa tattatttaa atcaatatgc tttaaagtct
    41821 agtttacaag cttgatatat atgatgtata atcaatatgt atgtctataa ttaaaacaat
    41881 tttgcaatcc tatagattga ttgtttaaag ttatataaag aatataaaaa agaataagag
    41941 agaggacgat taatatgaaa ttaggtatag ttggtttacc aaatgtaggt aaaagcacac
    42001 tatttaacgc aataactcaa gcaggtgcag aatctgcaaa ttaccctttt tgtacaatag
    42061 acccaaatgt gggagttgta tctgttccag atgaaagatt aaacaaacta caagaattat
    42121 ataattctga aaaaatagtt cctactgcta tagaattttg tgatatagca ggtttagtta
    42181 gaggagcttc taaaggagaa ggtttaggaa ataaattctt atcacatata agagaagttg
    42241 atgcaatagt tcatgttgtt agatgttttg aggatgaaaa tgttgtacat gtagatggtt
    42301 ctgtagaccc acttcgtgat atagaaacta taaacttaga attaattttc tcagatatag
    42361 agattcttga aagaagaatt aataaaactc aaaaagctgc taaggctgat aaaactttag
    42421 gttctgaact tgatttatta aaatcaataa tgtctacttt agaagaaagt aagtgtgtaa
    42481 gaactatgga atttacagaa gatgaacaaa cattcgtaaa ttcattggat ttacttacat
    42541 ctaagcctgt aatatatgct tcaaatgtat cagaagatga tttagctgat aatggagaaa
    42601 ataataaata tgttcaacaa gttaaagcat ttgcagaaac agaagatgcc gaagttgttg
    42661 tagtatgtgc acaaatagaa gcagaaattt ctgaacttga ttctgctgaa gaaaagaaag
    42721 agtttttaga aacattaggt cttgaacaat cagggcttga taagcttata aaatcttctt
    42781 atgctttact tggtttaatt tcattcttaa ctgctggtcc aaaagaagtt agagcatgga
    42841 ctataaaagt tggaagtaaa gctcctcagg caggaggaaa aatacattct gatatagaaa
    42901 gaggatttat cagagcagaa acaatagcct ttaatgattt ggttgagcat ggtactatgg
    42961 ctgctgctaa agaaaaaggg ttggttaaat tagaaggtaa agaatacata gttaaagatg
    43021 gagatgtaat attatttaga tttaatgttt aaaatgatta atcgtataca ctttgactat
    43081 tatatataat aactaaaaaa ctaagattat aat
//
LOCUS       DAEQAF010000024        42627 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.025, whole genome shotgun sequence.
ACCESSION   DAEQAF010000024 DAEQAF010000000
VERSION     DAEQAF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42627
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.025"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            203..3751
                     /locus_tag="KRN00_001397"
     CDS             203..3751
                     /locus_tag="KRN00_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1827264.1"
                     /translation="MMNRLKPRILGISILFIIIIILTCGAVFKFKFKLDNKLKETTHT
                     YLSEFTEHNIINLKTRLSGQFDMLESIANFIGNLNNINDEMVIDLMDSDVKRSSLIRM
                     TISTLDGECYSNDGITHNVQDRDYFKKAKNGEKNISEPLNSIVNNKEIIVLSTPVYKS
                     GKIVGVLSGIYDSKKLNELLGLSAFDEKADVFVAKKNGDIVAQKTNKNRKTLSCIFQL
                     FDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFMLNYQPLGVNDWYVFSVVPNKI
                     VSIQSENISYDVYIFALEILLVILIFIIYIACIINNNTKIIINEKEKFKVLTDNILGG
                     VKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNRFKDMIYKDDLDKFNCIILNQL
                     EKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSECIQGVLTDITELKKIQEELDSK
                     RFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMIGYTRKQLEDELNNKLIKLIFK
                     DDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWILLKGRKMIYDNGKSVLCCVIVD
                     ITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKDKMNISPNWYNKFKYDPITENA
                     TKNIIKSVDIYHDDMDKFISLIKLTSQGSEYEECEIRLRTRDTIYAWFSIKATTLFDN
                     NGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLYNKKASQSLIEEYITLDKKRKG
                     ALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLFRATDIVGRIGGDEFIVFIKDI
                     SETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIAKFPQDGMDYMTLFRNADIALY
                     SAKGKGKNCYTLYDKKFDKVQYITNTRNAGDSDNVEMSFKEHITNYIFDILYESSDIE
                     VAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEWCNEGVTSEINNLKNICYKDLG
                     NYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSILQCKILEGNEFRGFIGFDECSY
                     NRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLTIQKSVMDNMDIWAYVVDRNTY
                     ELLFINKKMLESAPNTHVGDLCYKAIWNNQDKPCKKCPMIYLKDGDDTYKSFMHNKKF
                     EVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            3936..5870
                     /locus_tag="KRN00_001398"
     CDS             3936..5870
                     /locus_tag="KRN00_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBH1827265.1"
                     /translation="MGNKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IDEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMADKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGTNKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5976..6971
                     /locus_tag="KRN00_001399"
     CDS             5976..6971
                     /locus_tag="KRN00_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1827266.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6943..7728
                     /locus_tag="KRN00_001400"
     CDS             6943..7728
                     /locus_tag="KRN00_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1827267.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            7716..8414
                     /locus_tag="KRN00_001401"
     CDS             7716..8414
                     /locus_tag="KRN00_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827268.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLEASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            8537..9010
                     /gene="ybaK"
                     /locus_tag="KRN00_001402"
     CDS             8537..9010
                     /gene="ybaK"
                     /locus_tag="KRN00_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBH1827269.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            9207..10046
                     /locus_tag="KRN00_001403"
     CDS             9207..10046
                     /locus_tag="KRN00_001403"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBH1827270.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            10059..10607
                     /locus_tag="KRN00_001404"
     CDS             10059..10607
                     /locus_tag="KRN00_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBH1827271.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            10673..11854
                     /locus_tag="KRN00_001405"
     CDS             10673..11854
                     /locus_tag="KRN00_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBH1827272.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEVKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQKEMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            12149..12535
                     /locus_tag="KRN00_001406"
     CDS             12149..12535
                     /locus_tag="KRN00_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1827273.1"
                     /translation="MEYKVNDQELNSSMFIPFVNRIWPGDYDMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVIPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            12685..12948
                     /locus_tag="KRN00_001407"
     CDS             12685..12948
                     /locus_tag="KRN00_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1827274.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(13077..13919)
                     /locus_tag="KRN00_001408"
     CDS             complement(13077..13919)
                     /locus_tag="KRN00_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1827275.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            14214..14948
                     /locus_tag="KRN00_001409"
     CDS             14214..14948
                     /locus_tag="KRN00_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1827276.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            14958..16091
                     /gene="nagA"
                     /locus_tag="KRN00_001410"
     CDS             14958..16091
                     /gene="nagA"
                     /locus_tag="KRN00_001410"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBH1827277.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGEVVYKNI"
     gene            16190..16939
                     /gene="nagB"
                     /locus_tag="KRN00_001411"
     CDS             16190..16939
                     /gene="nagB"
                     /locus_tag="KRN00_001411"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBH1827278.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            17114..17386
                     /locus_tag="KRN00_001412"
     CDS             17114..17386
                     /locus_tag="KRN00_001412"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827279.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKFCI"
     gene            18046..18750
                     /locus_tag="KRN00_001413"
     CDS             18046..18750
                     /locus_tag="KRN00_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827280.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            18752..20239
                     /locus_tag="KRN00_001414"
     CDS             18752..20239
                     /locus_tag="KRN00_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1827281.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQDKYLILFIDISKTLNLAQKINIVLISVMCF
                     AGILAIFTAVILSEKIAKPIKELCEFAKKMGQGDFKRTYFDFSDKELVELSTVMNKSA
                     EYLDKYDNEQKIFFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSD
                     MVEDLLYISKIDNITKDFELVECDLREVLSNCGARQNVRAINKGIKFIYEFDEEMVLF
                     ECDEKNISKAFMNLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFE
                     RFYKGVGGNHGIGLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            20444..22057
                     /locus_tag="KRN00_001415"
     CDS             20444..22057
                     /locus_tag="KRN00_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1827282.1"
                     /translation="MKEQLIFNITNLVTVVFEAFVIHMFLSDFLGQKEGYIKVVRYAK
                     LGFIICLGFCNLITLNPKITMPLIFILIFSTSFLYKGNLKTRLFTTVLLSIFFILSEI
                     VVTSIFVLFVKEGFEIMLENNSIRVLATILSKIVFLLTCKIICLFKKDVHLDMPIKYW
                     LPLFLIPIFSLFLSVSIFDVSKFFSLESLKFLSLISSVGILYINFIVFYLFKFIIDKT
                     KLSMKYELLEKEIIHKEELRLSNECYKIIVEQTDSVVFEWNIKENKSFVSQAWTEKFG
                     YNNACKNIFKEIKDKDLVHSEDKAIFEGFLESIKKKNMHNQAVYRLKKSNGEYIWCRT
                     SITSIYNDENELLRVVGVIVDVDSDIKKYEELRTRAESDSLTNIYNKGTFEKLVEETI
                     VMNTGDKKDALFIIDLDDFKEINDNFGHPFGDFVLKTFADKIQTSFGSKDLVGRIGGD
                     EFVVYMQDYVTEVNLHKKAKELNRVLSDNYTDLSFSFDASVSIGIARYPQDGTSFFEL
                     FKNADRALYSIKASGKNSYCLFEEELYVQ"
     gene            complement(22420..23250)
                     /locus_tag="KRN00_001416"
     CDS             complement(22420..23250)
                     /locus_tag="KRN00_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1827283.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKTYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            23323..25050
                     /locus_tag="KRN00_001417"
     CDS             23323..25050
                     /locus_tag="KRN00_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827284.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSEIAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGNKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSFSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            25087..26949
                     /locus_tag="KRN00_001418"
     CDS             25087..26949
                     /locus_tag="KRN00_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827285.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            27282..27971
                     /locus_tag="KRN00_001419"
     CDS             27282..27971
                     /locus_tag="KRN00_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBH1827286.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            28076..28762
                     /locus_tag="KRN00_001420"
     CDS             28076..28762
                     /locus_tag="KRN00_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBH1827287.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            28779..30686
                     /locus_tag="KRN00_001421"
     CDS             28779..30686
                     /locus_tag="KRN00_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBH1827288.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDTGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            31139..31828
                     /locus_tag="KRN00_001422"
     CDS             31139..31828
                     /locus_tag="KRN00_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827289.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADN
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            32264..32803
                     /locus_tag="KRN00_001423"
     CDS             32264..32803
                     /locus_tag="KRN00_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827290.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            32822..33865
                     /locus_tag="KRN00_001424"
     CDS             32822..33865
                     /locus_tag="KRN00_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827291.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            33867..34703
                     /locus_tag="KRN00_001425"
     CDS             33867..34703
                     /locus_tag="KRN00_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827292.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            34808..35482
                     /locus_tag="KRN00_001426"
     CDS             34808..35482
                     /locus_tag="KRN00_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827293.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            35482..36534
                     /locus_tag="KRN00_001427"
     CDS             35482..36534
                     /locus_tag="KRN00_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1827294.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            36764..37612
                     /locus_tag="KRN00_001428"
     CDS             36764..37612
                     /locus_tag="KRN00_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1827295.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            37602..39266
                     /locus_tag="KRN00_001429"
     CDS             37602..39266
                     /locus_tag="KRN00_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1827296.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFTLGINENS
                     YNNDKNTKNLISSLNSYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEDVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYMGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLDKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     ITKGDTRFKSISNISKILIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            39315..40571
                     /locus_tag="KRN00_001430"
     CDS             39315..40571
                     /locus_tag="KRN00_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1827297.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            40594..>42627
                     /locus_tag="KRN00_001431"
     CDS             40594..>42627
                     /locus_tag="KRN00_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBH1827298.1"
                     /translation="MKKFIISIISLVLFFSNISIIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEAEDLAYNLKSKKEVKDSSWNMSINKTTKVFLMISFITIIV"
BASE COUNT        16931 a         4340 c         7386 g        13970 t
ORIGIN      
        1 gttataattt ttaatattaa ttaagaatga tgaaatatga ataaagattt tacaaataaa
       61 tcttaagcta tcttatttaa ttctaataca ggaagaaggt aaatgtatat tgaaaaaatc
      121 atagaaatag aagtaaacaa tttaaataaa tacaaaggtt tgcaaaagaa gtaatataat
      181 tatatacaat gaggatgtga gtatgatgaa cagactaaag ccaagaattt taggtattag
      241 tatcttgttt attattataa ttattttaac atgtggagct gttttcaagt ttaaatttaa
      301 attagataat aaattaaaag aaaccacaca tacatatttg tctgagttta cagaacacaa
      361 tataattaat ctcaagacaa gacttagtgg tcaatttgac atgcttgaat ctattgctaa
      421 cttcatagga aacttgaata atataaatga tgaaatggtg attgatttaa tggattctga
      481 tgtaaagcga agttctttaa ttagaatgac tatctctaca ttagatgggg aatgttattc
      541 taatgatgga attacccata atgttcaaga tagagattat tttaaaaaag ctaaaaatgg
      601 agaaaagaat atatcagagc ctttaaattc tattgttaat aataaagaaa taatagtttt
      661 atctacccca gtttataaaa gtgggaaaat agttggtgtt ttaagtggaa tttatgattc
      721 aaaaaagtta aatgagttat taggattatc tgcatttgat gaaaaagcag atgtttttgt
      781 tgcaaagaaa aatggagata tagttgctca aaaaacaaat aaaaatagaa agacgctatc
      841 atgtatattt cagctttttg acaaagataa ttgtgatgaa gatgattgtc taaaaactat
      901 aaaagaaaat atgaaaaatg ataagtctgg atattttaat tataacttag ataatgaaaa
      961 atttatgtta aactatcagc cacttggagt taatgattgg tatgtttttt ctgttgtgcc
     1021 aaataaaata gtatctattc agtcagagaa tatatcttat gatgtatata tttttgcatt
     1081 agaaatacta ctagttatat tgatttttat aatatatata gcatgtatta taaataataa
     1141 caccaaaatt attataaatg aaaaagaaaa atttaaagta ctcactgata atatattagg
     1201 aggggttaaa acctgtttaa aagatgaata tatgactatg acatatgtaa gtcaggggtt
     1261 tttagagctt acaggttact cttgtgaaga tttaaataaa atatttaaaa atagatttaa
     1321 agacatgatt tataaagatg atttagacaa gtttaattgt attattctaa atcaattaga
     1381 aaaacaagat aaaattgaag ttgaatatag aattgtaaga aaagatggaa gtataatttg
     1441 gattttggag agaagtaagt ctataaatga taataaagga agtgagtgta ttcagggagt
     1501 tttaactgat ataacagaac ttaagaaaat acaagaagaa ttagattcaa aaagatttga
     1561 aatacaggct atcaatgata gtattgttgg tggaatagtg ataactgaga taaatgatga
     1621 ttttgatagt atatatttaa atgaaggtta tttaaatatg attggatata cacgcaaaca
     1681 actggaagat gagctaaata ataaattaat caaacttatt tttaaagatg atagaacaga
     1741 attaattaat agtataaaca aacaactcaa attaagtgat acatttgcat ctgaacaaag
     1801 agttgaaaaa agggatggca ctattatatg gattttatta aaaggaagaa agatgattta
     1861 tgataatgga aaatctgtac tttgttgtgt tattgtagat attacttctg ctaaattatt
     1921 agagcaagaa cttaaaaaga gtgaagaacg tcatgaaatc attctaaagc agacgcaaaa
     1981 tattataata gaatgggata tagaaaaaga taaaatgaat atatcaccta attggtataa
     2041 taagtttaaa tatgacccta taactgaaaa cgcaacaaaa aatataatta aatcagtaga
     2101 tatatatcat gatgatatgg ataagtttat ttcattaatt aaacttactt cacaaggtag
     2161 tgagtatgaa gagtgtgaaa ttagacttag aactagagat actatttacg cttggtttag
     2221 tataaaggca acaactttat ttgataataa tggtaaacct tataaagtag taggaagttt
     2281 gactgatatt gatgaatcaa aacgagaagc tgaaaagttg aaagaaaggg cagaaaaaga
     2341 ccctcttaca gatctgtata ataaaaaagc atcacaatca cttatagagg agtacataac
     2401 attggataaa aaaagaaaag gtgctttaat gattattgat attgatgact ttaaaggaat
     2461 aaatgataat ttaggacatt tatatgggga tgctgtatta agtgaaattg caaatgacct
     2521 aataaatcta tttagagcaa ccgatatagt aggcagaatt ggtggagatg agtttattgt
     2581 atttataaaa gatatttctg aaacaagaga tattataaat aaagcagaag aattggtaaa
     2641 aacatttgaa aggtcttttt taggtaaagg acgaaattat aaaatatcat taagtgtagg
     2701 aattgctaag tttccacaag atggtatgga ctatatgaca ctatttagaa atgcggatat
     2761 agctctttac tcagccaaag ggaagggcaa gaattgttat acattgtatg ataaaaaatt
     2821 tgataaagtc caatatataa ctaatacaag aaatgcagga gatagtgata atgtagagat
     2881 gtcttttaaa gaacatatca caaattatat atttgatata ctatatgaat caagtgatat
     2941 agaagtggca gtaaatttaa ttctaagtat tgtaggtaaa cactttaatg tgagtcgcat
     3001 gtatatattt gaaaattcag atgataatcg agtatgtaaa aatacatttg aatggtgtaa
     3061 cgaaggtgta acctcggaaa ttaataatct taaaaatatt tgttacaagg atttaggcaa
     3121 ctatctttta aattttaatg cagatgggtt attttattgt aatgatattg aaaatttagg
     3181 tagtgatgtg aaaaaagtac ttaagccaca aggcatacgt tcaatattac aatgtaaaat
     3241 tttagagggt aatgaattta gagggttcat aggatttgat gaatgttcat ataatcgtat
     3301 gtggactaat gatgaagtga acactttgac atttatatct aaaacgctca gtatgttttt
     3361 attaaaaatg cgtattcaga gtaagctaga agagtcttta acaattcaaa aatctgtgat
     3421 ggataatatg gatatatggg catatgttgt tgacaggaat acctatgaat tactatttat
     3481 caataaaaaa atgcttgagt cagcaccaaa cactcatgta ggtgatttat gttataaagc
     3541 gatatggaat aatcaagata aaccttgtaa aaaatgccct atgatatatt taaaagatgg
     3601 tgatgatact tataaatcat tcatgcataa taaaaagttt gaggtacagg caaatataac
     3661 tacaactact ttgaaatggt ttgatggtaa agatgcatgt ttaatatttg gaagtgaaat
     3721 aactagtatt gaagctgaag aaaatactta aaatactgtg ttatatatat acttaaaatc
     3781 gcaatttgaa tttattagac ttaaaatgtc tatataaatc atttaagttg tggttttaag
     3841 tattttttat gatataatta agcgttaaga acaaaattaa aagatacttt tgtataaaaa
     3901 aatatttgtt aaatatatat tgagcaggtg ataatatggg aaataagttt ttaccaataa
     3961 gcaaacaaga tatgatagat agaggatggg aagaattaga ttttgttcta gttacaggag
     4021 atgcttatgt ggaccatcat agttttggaa cagcaataat atctagagtt ttagaaagtg
     4081 ctgggtataa agttggaata atagctcaac cagactggag aactacagat gattttatga
     4141 agctaggaaa acctagactt gcatttctag ttaatgcagg aaatatggat tcaatggtca
     4201 atcattattc tgtaagtaaa aagcatagag aaaaggatat gtattctcca ggtgggaaaa
     4261 tgggttatag accagataga gctactatag tatattgcaa taaaataaga gaagcataca
     4321 gtgatgttgc aatagtaata ggtggaattg aagcgagctt aagaagattt gcacactatg
     4381 attattggag tgataaggtt agaaagtcta tgttaataga tagtggagca gatttattag
     4441 tttatggtat gagtgaaaag cagattgtag aagtagccaa tgcacttaat gatggatatg
     4501 acccaaaata cattagacat attgatggga catgctatat ttcagataca ttggaagaaa
     4561 tatatgataa atatatatta attccatcat ataaagaaat ttgtgaagat aaaatgaagt
     4621 atgtagaagc ttttaaaatt caatatgatg agcaagaccc atttagaggt aatataattg
     4681 ttcaacctca tggaagtaag tatctggttc aaaataagcc agaaaaacca cttagtagag
     4741 aagaactaga tgaagtatat ggattaccat atcagaagac ataccatcct gtgtatgaaa
     4801 aatttggagg aataccagct atagaagaag taaaatttag tatagtaagt tcaagaggct
     4861 gttttggtag ttgttcattt tgtgcaataa catttcatca aggtagagca gtgcaaagta
     4921 gaagtgaaaa atcaattatt gatgaagcaa taggaataac aaatttagat gattttaaag
     4981 ggtatataca tgatgttgga ggtccaacag ctaattttag aagaccagca tgtaaaaaac
     5041 aaattactaa aggtgcttgt aaaaatagac aatgcttatc tccatcacca tgtaaaaatt
     5101 tagatgcaga ccacagtgaa tacctacatt tacttagagc tgtaagaaaa ttacctaaaa
     5161 taaaaaaggt gtttgtgcgt tctggaatta gatacgatta tgtaatggca gataagaaca
     5221 ataaatttct tagagagttg atagagcatc atgtaagtgg tcagttaaag gtagccccag
     5281 aacatatatc agaagaagtt ttaaagtata tgcaaaaacc agcaggaaaa acttatgata
     5341 aatttagaca gaagtttttt gctataaatg aagaattagg taaaaagcaa tatttgatac
     5401 cctatttaat gtctagtcac cctggttcta ccttaaatag cgctatagag ttagcagagt
     5461 atttaagaga tactcactac caaccagagc aggttcagga tttttatcca actccaggga
     5521 ctctatctac aaccatgttt tatacaggta ttgacccgct tacaatgaag ccagtttatg
     5581 ttcctaaatc aaaacgtgac aaggcaatgc aaagggcttt attacaatat agagcaccta
     5641 gaaattatga tttggtatac tctgcgttag ttgaagcagg aagagaagac ttaattggtt
     5701 ttggacatag atgtcttata aagccaaaaa atgaaaagcc ttattttaat agaaataatt
     5761 ctaaaaaaaa tgtatctaaa ggaacaaata aaaacaaaaa aactaataca aataacagaa
     5821 gtaataaaaa tcaacaaaaa agttcaacta aaaaaaagaa aaaacattaa agtataaata
     5881 aaaatactta aaaaagaagg attattcgat aaattaacag aaattagtat aaataaatat
     5941 aattatttta atgacgttac ctttgggagg aagagatgaa aaagtatatt tctataatat
     6001 tattagtggt gttgactatg gttgttttgg taggatgttc accaggaaaa gataacccta
     6061 aaaataagga gctatcagtt gtcaaacaag taaaagtagc tgttccagat ggactaccag
     6121 cagtggcaat agctaaactt gcaaatgaaa atccagagat taaagaagga tatgaaacag
     6181 tgtatagcat tgaaaagaca cctgaagcga tttccactag agtgatgaaa aaagatgcag
     6241 atatagctat agttccttca aacatggctg caatagcgta taataaaact tcatcatata
     6301 atattgttgg aactgtagga atgggttcac tttatttggt gtcaacagaa aatataaaag
     6361 attattctga tttagttggt aaagaagttg gatgtactgg aaaaggactt actccagaca
     6421 taactataaa aagtcttttg ttacaaaagg atataaatta ttcagatata aaatttaatt
     6481 atgtaaattc agcaagtgaa ctggtaccat tattggctac tggtaaagtt aaaacaggta
     6541 ttgttccaga acctgcactt agtgctttga tgtctaaaaa tccagacata aaaattataa
     6601 aaagtttaaa tgactcatgg aaggaagtaa gtggttcaaa agatggttat cctcaatcta
     6661 ctttaattgt aaagtctgaa tttttaagag ataataaaga ttttgttgat tcttttgtag
     6721 gtcaattatc aaatagtata gattgggcaa acaaaaatcc tgaagaatta ggtgcatatt
     6781 ctgaaaaaat aaaaatatct actgaatcaa agataatagg aaaatctctt gaaagagcta
     6841 atttgaaata tattccagtt aaggacatga ttaaagatta taaaaattac tatgagaaat
     6901 tagctaattt tgatgataag acattaggag gcaaagtacc agatgaagca atatactttg
     6961 ttgagaaata aaaaaaataa agaacaattt atagataaaa tggaggtaac actttcttgt
     7021 gttatcctct tatttttatg gcaaattatt gctttaaaaa ttgataatga tattttttta
     7081 ccaacagtag gtcaagtgtt taatagtata aaagagatta tgctaaattc tagtttctat
     7141 atagatatac tttactctat ggggagatgt ttttttagtt ttttactggc tatgattttt
     7201 gctattatac tttcaatagt gtcttattta aatagatttt ttagaaactt attaaagcca
     7261 atcaatgctt tgacacgttc aataccaact atgatattgg tagtacttgc acttatttgg
     7321 tttgaaaagg atagtacccc ttttatagtt ggatttacta tagtttttcc tatattgtat
     7381 gataacgttt tgggcgctat attgaatata gacaagaact tattagaaat ggctaatgtg
     7441 tataaaataa ggtttataga taaggtgtta aaaatttatt taccagccat aaaatttcaa
     7501 attatatcta tactagtatc aacattctct ttaagtttga aagttgctat agcaggagag
     7561 gtatatagtc aacctacata tggtattgga actatgatac agactgaaaa aattaacttt
     7621 aacacatctg gaatatttgc atggataatt attgttcttt taatatctgc tattttacaa
     7681 atagctcaaa agtttttagc aaggagagct tttttatgga aaagataaag ttgagtattg
     7741 aaaatataaa taaaagatat gatagtcgta ttatatttag agattttaat attgattttt
     7801 atgtaaatga ggtaaattgt atccttggaa aatctggttg tggaaaaact acactcttga
     7861 acataataag tgggattatt aaaaatgaca ccaacaatct aaatatcaaa gaaaatttaa
     7921 atcgagtagg aaataagctt gaagctagtt acatatttca agatgataga cttatagact
     7981 ggttaacagt agaagaaaat ataaagatag ttgtaaataa atactataat aaaactcaat
     8041 taaataaaat ttgtgatgaa tacttggaat tggttggaat tagtgattat aaaaaattct
     8101 atcctcaaat gcttagtgga ggtattagac aaagagtaaa tattgctaga gcttttatat
     8161 atccatcaaa aaacattata atggatgaac cttttaaatc tattgatgca aagaatacac
     8221 agcttataat ggataatttt agaaatatat taagaaaaga aaagagaact gtgttatttg
     8281 taactcataa tattgaggaa gcattgtttt tagcagatag gatatttatt ttaggagact
     8341 ctccaattag aataaaaaaa atattaaaaa attctaagga attggaaaaa aatgaagttt
     8401 tgaagttgat atagagttat aataatactg tcgttttaaa agatatttgg ttaaaatcta
     8461 taagactata ttaaaatagt acagaatatt caaaactgtg tataatgttc gtattttata
     8521 aaaaggaagt gaatgtatgg ttaagactaa tgctatgaga atattagatt caaataagat
     8581 tgattataaa gtaatgtctt atgaagtgaa aagtgaacat gtggatggtg ttgaggtggc
     8641 acatgatata ggaagagatg taaatgaagt gtataagaca ttagtaactc aaggagttag
     8701 taagaatata tatgtatatg taataccagt acatgaaaac ttagacttaa aaaaggctgc
     8761 aaaagtagct aaagagaaaa gtgtagagat gattcatgta aaagatataa ataagcttac
     8821 aggttatatt agaggcggat gttctcctat aggtatgaaa aagctttata aaacttttgt
     8881 aaatgaaagt gcaaagaatt tagatacaat tattgtgagt gcaggaaaaa taggatatca
     8941 aatagaacta tctccatttg atttacaaag acttataaaa gtagaatttg tagatgtaat
     9001 aaaaaaataa gaattacata taaaatatag agcttatatt ctcaataata ggtgttgtag
     9061 tattaataaa atgaataaga attttaaaat aaatattcag ttacttatgt gtaattggta
     9121 taaaaatatt gagaaatttt aaaaacaatg gtaaagtgta agtataatca cgaatatttt
     9181 ttataaagta atggagggat gttcgcttga gaaaaataaa atctgaacaa atcgtcgagc
     9241 aggtaaaaaa actttgtata gaagcgagcc tatatttagg agaagatgtt ttaagttgta
     9301 taaaagaaaa agcgaaaagc gaaaagagtg aagttggaaa aaatatattg aatatattag
     9361 ttgaaaatgc tgaaatagct aaagaaaaaa atataccaat atgccaagat actggtatgg
     9421 ctgtattttt tgttgaaata ggacaagaag ttttaattga aggagacaca cttactgatg
     9481 ctataaatga gggagtaaga caagggtatg aagaaggcta cttaagaaaa tctgttgtaa
     9541 gtccaattaa cagagtaaat acaaaagata atacacctgc tgttattcat tatgatatgg
     9601 taaaaggtga taaaattaaa atagaatttg cagctaaggg atttggaagc gaaaatatga
     9661 gtaagatgaa aatgttaaag ccatcagatg gattggaagg aattaaaaaa ttcataatag
     9721 atacagtttc agaagctgga cctaacccat gtcctcctat ggtaattgga gttggtatag
     9781 gtgggactgt ggacaaatgt gctcaaatag ctaaaaaggc actttttaga gaactaggtg
     9841 aatttaataa ggacgaaaat atagcaaaac ttgaaagtga actattaaca gctattaata
     9901 aacttggtat aggacctcaa ggcttaggtg gtactacaac agctttggga ttaaacatag
     9961 agacttttcc tacacacata gcaggtctac ctgttgttgt aaatataaac tgccatgcat
    10021 caagacataa gaaggtagta atttaggagg aaaataaaat gataaaaata actacacctg
    10081 taaatgaaat tgatatagca aaattaaatt gtggagatac aattagtttg agtggtatac
    10141 tttatacagc aagagatgct gctcataaaa gattgataga ttgtataaat aaaggtgaag
    10201 aattaccatt tgacgtatat ggtcaaggaa tatattatgt aggacctact cctacaaagc
    10261 caggagaagt tataggtgct gcaggtccaa cgacgagtta tagaatggat gatttgacta
    10321 tacctctttt agaaagaggt cttagattga tgataggcaa gggaaaaaga agtgatgaag
    10381 ttatagaagg tatgcaaaaa tacggagcag tttatcttgc tgcaatagga ggagctggag
    10441 cgtatatttc aaattcaata aaatcatgtg aaattattgc atatgaagat ttaggagctg
    10501 aagctataag aaagattgta gtagaagacc ttaagcttac agtagcaata gatagctatg
    10561 gaaataatat atatgagcaa ggtcgagcaa tttatgaatg taaataatgt ttagaaataa
    10621 atatgaatat caaaattaaa aatagttgtg tatattttaa ggaggaaaat tgatgtctaa
    10681 ggattatgca aaattggcat tagaaatgca tgaaatcaac aaagggaaag taagtgtaga
    10741 aagcaaggta gaagttaaaa ctaaggatga tttatcaaca gcatatacac caggggttgc
    10801 tgaaccttgt ttaaaaatac atgaaaatca agatgatgtt tatagataca cttctaaagg
    10861 gaatctagta gcagtagtta gtgatggaag tgctgtactt ggattaggta acattggtgc
    10921 tgaagcatct atacctgtta tggaaggtaa agctatatta tttaaacaat ttgcagatgt
    10981 agacgctttt ccaatatgtt taaagactaa tgatgtagat gagatagtta aatctgtaga
    11041 gttgatggag cctgtatttg gaggtataaa tttggaagac atatcttctc caagatgttt
    11101 tgagatagaa gagagattaa aaaaatcttt aagtatacct gtttttcatg atgaccaaca
    11161 tgggacagca ataatagttg cagcagccat aataaactca ataaagttaa ttgaaaataa
    11221 aaaaatagaa gatttagaaa tagttataaa cggagcagga gctgctggta tagccatagc
    11281 aaagatacta cttaatatga atgttaaaaa tataatttta tgtgatagaa gtggagcatt
    11341 ggaagctagt atagaaaatc taaactatgt tcaaaaagaa atgttaaaag taacaaatat
    11401 aagaaatgaa aaaggacctt taaaagatat tataaaagga aaagatgtat ttattggtgt
    11461 ttcaggtcca ggagctgtta caaaggaaat ggttgaaagt atgtctgaga agccaataat
    11521 attggcaatg gcaaatccta ctccagagat aatgccagaa gaagcaaaat taggtggagc
    11581 atttataatg ggaacaggtc gttcagactt ccctaatcaa gtcaataatg tactggcttt
    11641 tcctggaata tttagaggtg cacttgatgt taaggctaaa gagataaatg aagaaatgaa
    11701 gatagctgct gcatatgcaa ttgctaatac aataagtgat gaagaaatat gcccagagta
    11761 tatattacca gatgtattta ataagaatgt agtaaaaaat gttgctaagg cagttaaaga
    11821 agcagcgata aaaaccaaag taaatagaat ataaattttt atatgttcat atatccttat
    11881 cttatcgggt atatgggcat ttttattata ggtttatact catatatcct tacttttata
    11941 tacatatctt tatgattaaa ggtgttagaa aatgtagtaa attttatact atcagactct
    12001 atctttatta ctttagtaga tacatggttg taaaggttta tagaaaaaaa tataggaagg
    12061 cagattttta ttgttgcgta tatatgagaa tgatataata tgaatattat aaattaataa
    12121 atttaaattt atggaggtac aagagatgat ggaatataaa gttaatgacc aagaacttaa
    12181 ttcttcaatg tttatcccat tcgtcaacag gatatggcca ggagattatg atatggataa
    12241 aacacagact gcattatcaa aaactttgaa tataactgct tatgatgata aagtgcttgt
    12301 aggatgtctg cgagttcttt cagatggtta ttattttgga acaattacag aattgcttgt
    12361 tattccagag tatcagaaac aaggcattgg tagtaagctt ttccagcttg ctaaagagaa
    12421 caccccaact atgctatatt ttggtgcaca gccaggagta gaagagttct atgaaaaaaa
    12481 tgggtgccaa agaagtctgc aatcctacat aataaaaaag aaagatagtt attaaagttc
    12541 cagctttcaa taatcttaaa agtacaatat tttagtggaa tcatttcatt ttttattact
    12601 aatatgacat aaacatgtca tattagtatt gatatacttt taatatggtt aagagccaaa
    12661 gaaaaatata aggagtgatt taaaatggaa gaaactaaat tttgccaatg ctgtgcaatg
    12721 ccaatgggac aaactgatga attatatggg acaaataaag atggaagtaa aagtactgat
    12781 tattgtagtt attgttttaa agatggtgag tttacagctg atataagtat ggaagagatg
    12841 atagaagttt gtatccctca tatgcttcaa agtaataagg atatgactga agatgaagca
    12901 agaacaatga tgaacaattt ctttccaaca ttaaaacgct ggaaataatt ttatgcaaaa
    12961 ttagttatat gcaaaacatg aaatatggtg ttgagaataa gaggtggtgt gctttatagc
    13021 ataccacctg ttttgttact tggagttcag ttattttcct aaatatttta aatatactat
    13081 tttagataag ttccctcttc atcttgataa attaatcctt ttttcataag cactccaaga
    13141 gctcgtttaa aatttttctt acttgaatta aataatatag aaatatcttt agggtcagat
    13201 ttatcattaa atctcatata tccatcagaa ccttctaaat aacttaaaat cttattttct
    13261 aaagtatcaa gttcatcctt tctatttcct ctaggagaaa gaccaagttt tccatcttca
    13321 tatattttta tgacatgtaa attttcaaga acatcaccag tttttagttc agtaaagtac
    13381 tcattatgaa gtattacacc agcatattta ttgtctacac atatcattgc agaattatta
    13441 gtttggaatc catatacaac tccagttaca atatctccta cattgtaagt atggtctgtt
    13501 aataagtatg aatctatatc tgtagtagca gcaattcttt tgcttttgtc taaatatata
    13561 taaaataaat atttttcgtc tctaaatagt ggataagtct tagctttaaa aggaactaat
    13621 atgtctttag gaagtcccat atctataaaa gtaccaatgt ctgtattatc aactactttt
    13681 aaatgtgcta catccccaac cttagctaaa ggcggtatta aagttgcagc agttctgtca
    13741 tcagaatctt taaatatgaa agcatttact tcatcaccta tgtttatttc atttttcccg
    13801 attaatctat tatgaagaag tatatcgtct tttgtgttat tagtttgtcc atccaaaaaa
    13861 tatccaaatt cagtttttct ttttactgta agtttattaa aatcacctat gtttatcaaa
    13921 ttaaaatcat cctctcattt tatatttata atttagccat aatatactta tgtagtagtt
    13981 tgtcacagta tctatattag tattagtgaa atttacaata aataatatag ttatttatgt
    14041 atttttcaat tctctagctt cttatatagt ataaactcca atttcttttt tgtctttagg
    14101 ttttattaaa atttttacaa aataagttaa aaagtattga aataaaattt cttttaaagt
    14161 ataattggta tataccaaaa ttggtatata ccatatcgaa aagtggtgac tatatgaaaa
    14221 tagtaaataa atctagtaat ataccattgc atactcaatt aagttcaata ataagagaga
    14281 tgatagaaac tggtgagctt aaagagggcg atgcaataat gccagaaaga gaactttgta
    14341 acatacaaaa tgtaagtcgt atgacagtaa ataaaaccat tgttggatta gttacagaag
    14401 gacttcttta tagggtacaa ggtaaaggga cattcgttgc aaagcaaaaa aagaagtatc
    14461 agttttcaaa tgtaaaaggt tttactgatg ttatgaaaga aaagggagta aacataaaaa
    14521 cggatatatt atcctttgag atggaactac cagatgattt agttaaaaga aagcttggaa
    14581 taagtgataa tactacaaat atatataaga ttgtcagact tagatatact gatggagagc
    14641 catttggatt agaaatagta tatctatcag aagaaatgtg taagggtcta acaaaaggga
    14701 tattggataa ttcttcatta tatagggttt taaatgaaaa atatggctat aagatacaaa
    14761 aagctgaaca ggtaatggag ccagtaatac tttcagatga agaaagtaag cttcttgaaa
    14821 cagatgaagg tgctttagct cttaaacttc atagaaattc ctataataga gaaggtagcc
    14881 ctatagaata taccatatca atatttagaa cagataaata tcaatatgaa atagtattga
    14941 gtgagtaggt gaataatatg aaatgtttaa ttaatggaaa gataatatta aaaaatcaaa
    15001 tcttagaaaa taaagtatta gtatttgatg aaaaaataat tgatatagct gatagtgtac
    15061 caaaagattg tgaagttata gatgctgatg gaaaatatat atctccaggg cttattgata
    15121 ttcatataca tggaaacatg ggaaaagata caatggattc gactgatgaa tctattgaaa
    15181 caatttcaaa gtcaattatg agacatggag taacatcttt tctgccaact acaatgacta
    15241 tggataaaga acatgtttat gatgcacttg aagttattaa aaaagcccaa aatagaaagc
    15301 ttgaaggggc acaagtatta ggagcacatt tagaaggacc ttttataaat gagaattata
    15361 agggagcaca aaatgaaaaa tttataataa attcaaaata cgaatttata aaagaatata
    15421 aagatgttat aaaagttata acttatgctc cagaaaaaga tattgatttt gattttacta
    15481 gagaaataaa aagatgtaca gatatagttt tatctattgg tcatagtaat gcaaattatg
    15541 accaagctaa agaagctata aatttaggag taactaatgt aactcacatg ttcaatgcaa
    15601 tgactggttt aaaccataga gacccaggcg ttgttggtgc agcacttaca actaatgtgt
    15661 acagtgagtt aatagcagat acaatccata taaataaaga tttatttcaa tttatactaa
    15721 ataataaagg aaaagaaaga ctgattttaa taacagattc tatagaagct ggaggtcttg
    15781 aagatggcaa ttattctctt ggaggtcaga aagtcatagt taagggtaat gaagctagac
    15841 ttgaaaatgg agcattagct ggaagtgtgt tgtctttaaa taaaatggta tttaacttct
    15901 tagataatac aaaccttaaa gtgaatgaag caattaattt agcttcttta aatccagcaa
    15961 catctttggg aataaatgac aaaaaaggaa gcttagaaat aggtaaggat gcagatatag
    16021 ctgtatttga tgagaattta gattgtaaaa tgacactttg cttgggggaa gtagtatata
    16081 aaaatatata gtatacaaaa caaactttaa aaacagtaaa aacaatataa aaaataataa
    16141 attaaactta cattagttaa agtagtagtt aaaatttagg aggaataaga tgagagtatt
    16201 agtgtgtaaa gattatgatg gaatgagtaa aaaagccgct gaaatgatag cagctcaaat
    16261 agttttaaaa ccaaattcaa tactgggact agctacagga agtacaccag taggtatgta
    16321 tagagattta gtaaaaaaat acaatgataa tatagtagat ttttcagatg tgatgagctt
    16381 taatttagat gaatattata agttaccaat atctaatgac caaagctatg attattttat
    16441 gaaagagaat ctatttaatc atgtaaacat aaagccagaa aatactcatc taccaaatgg
    16501 aatggctgat gatattgaaa aagagtgtat gaactatgaa gcttctatag atgcagctgg
    16561 tggtatagat gtacaagtac ttggaatagg tcgtaatgct catataggtt ttaatgaacc
    16621 tgatactaaa tttgcaaaaa gaactcatgt agttgaactt acagagtcta caatagaagc
    16681 taatgcaaga ttctttaaat caagagaaga tgttcctaaa aaagctgtaa gtatgggaat
    16741 aggttcaata ttgaagtcta agaaaatatt gcttttagct tcaggagaag aaaaagctga
    16801 tgcagtatat aatactgttt atggagatat aactccagaa gttcctggtt ctatacttca
    16861 acttcataaa gacactatag ttatagtaga tgaagcagca gcaagtaaat tgaatccaaa
    16921 agattataaa ttagtataag aatagaatgt agtttaagta aaaaatagct atcattgagt
    16981 aatcaaattt atttaatgat agctattttt atttaaattt tttacttctt tttatttaaa
    17041 ttagttatta ttgtttaaat tacttgctta ttacttttta cgaaaactcg ttatcaagaa
    17101 gtatccaaat aagatgttaa aaattattat gtttagtggg attctatcaa gtataataaa
    17161 attacctata attgggatat taccaactgg aaacataaag aagaatacag gcatcagtga
    17221 tagtaaaaaa gatggaaaac aaagaagaag taatcttgga atatcaatat accaactacc
    17281 atcctttttg tattctctaa tcaataattc agttcctagt aataaaccaa taccaccaga
    17341 ggaaattaaa ttaataaaaa tgtatctttt aaagttttgc atataaccag tgtgaaattg
    17401 agtatagaaa tcataattta atttaacggc taaaaaatac ataagcaata gaatgattaa
    17461 aaataaaaga tatctaagag cttttttcat tttaaattct cccttcagaa atactttatt
    17521 cagctttatt ttgttggaat ctgattttat catttagttt aagaaatcca taatattagt
    17581 gaagaatgaa ataagtatta tatatgaata aatattttta gaattaaggt gaactgtagt
    17641 gcttaatata actataatat taattatttg aatattcaat aaaaagtttg aaaaatatca
    17701 attttgatat aaactgaata aatacagttg aatattaaat tattatttta tcaaaaatat
    17761 gcaaagtact acaccttcaa atatcaccta aagtaattaa aaggcaatta aagtgaagta
    17821 gttcaagtat ttctaaaata agtttaataa attctataat aatttatttt ttgccttaaa
    17881 attgccttaa aatccaaaca attttaaaac taatgtacta taaaaagctg gtataattta
    17941 aatatagtaa aaaataagat ttatcttatc tattgggatt taattattta atcaatatat
    18001 ttataccatt taatttaaat aaaaagtcta ttaaggagtg agcttatgag taagttaatt
    18061 tatatagcag atgatgaaga taatataaga aatttggtaa agacattctt aaaaaatgaa
    18121 ggtcatgatg ttatggattt taaaacgggt gatgaacttt tagaacaatt taatataaag
    18181 gagtgtgact tagtaatact agatataatg atgcctggat caagtggttt tgaagtatgt
    18241 acaaaacttc gtgagaaaag tacagtccca ataatcatgc ttactgcaag agatacagat
    18301 atagattata ttacagggat aaccttaggt agtgatgatt attttacaaa accatttagc
    18361 ccaatgtctt tggttatgag agtaaaatct atatttagaa ggatagagtt tgaaaagaaa
    18421 caaaattatg ataaatatag taactcgata gatatggaat taaaatttgg tgatgtaata
    18481 ataaataaaa agaataaaat cgttacaagt aaaaatgtaa atatagacct tacaccaaat
    18541 gaatataacc tattgactta tttgtttgaa aatatagata gagcagtttc cagagatgaa
    18601 ttattaaaca aaatatgggg atacgatata gaagttgaga caagggctgc tgatgataca
    18661 gtgaagagat tacgtaaaaa aattttaaat acaaatattt taatagaaac tgtatggggg
    18721 tttggattta ggttgaagga gaaaagttaa gatgaagaat ggaaatgaca agaatagaat
    18781 tggaaagatt aaatccaaat ttaaattaaa gttctcaaag aaaaatataa gcataaaaac
    18841 taggattttg ttgagtatac tttgtttgat aattatagta tttatgataa tattagtatc
    18901 ttttaatgta tttcttgata catatataaa aacaactgcg aatgaagaat tgacaaagtc
    18961 tacagaaata gtagaacata tggatagtaa ttttagacct attaagccac cacaagatga
    19021 tggaaagctt cctcccaaag tattatctaa ttttatgaga aatgtacaag ataaagttag
    19081 gatggcagaa acacaatcag atgctgatgc tatggtagtt gattctaagt ataacctgat
    19141 atttccaaca agagaggacg atttcttaaa aaatgttgat gagatggagc tgattaggga
    19201 gtgtattcaa aatgaaaaat tagatttaaa ttcagatgaa aatacacgga tatctaccag
    19261 aaataaggat tattatattt caactgtaaa aattaccagt atatatggtg aacaagacaa
    19321 gtatcttata ctttttatag acatatcaaa aactctaaat ctagcacaaa agataaatat
    19381 tgtattaata tctgtaatgt gttttgctgg aatattagca atatttacag ctgtgatttt
    19441 atctgagaaa attgctaaac cgataaaaga gttgtgtgag tttgcaaaaa aaatgggtca
    19501 aggagatttc aaaagaacct actttgactt ttcagataaa gaattagtag agctctcaac
    19561 tgttatgaat aagagtgctg agtatctgga taagtatgat aatgaacaaa aaatattttt
    19621 tcaaaatgca tctcatgaat taaggacacc acttatgtct attaaaggtt atgcagaagc
    19681 tataaaatat aatgttatag atagtaaaca tgcaagtgat ataattcttg aagaaagtga
    19741 taggttaagt gatatggttg aagatttatt atacatttct aaaatagata atataactaa
    19801 agattttgaa cttgtagaat gtgatttaag agaagtactt tcaaattgtg gagctaggca
    19861 aaatgtaaga gctataaata aggggataaa atttatttat gaatttgatg aagaaatggt
    19921 tttatttgaa tgtgatgaaa aaaacatttc caaagcattt atgaatctta tagaaaatgc
    19981 tttgagatac gctaagagtg aaataaaaat agtgtgtaag tataatcaaa aaaatatagt
    20041 tgtgataata gaagatgatg gaattggaat caagaaagaa gatttacctc atgtttttga
    20101 aagattctat aagggagtag gaggaaatca tggaattgga ttatcaatag ttaaatctat
    20161 tgtaaataag catggtgggc gtatatacgt agaaaatggc aaaaaaggag ctaaatttac
    20221 tatattattt aaattgtaaa aaaattagag aaaatataga gatgtttgaa gttgtttttt
    20281 atatatatct gttgtatact gttgaaaaaa gaacaatatt aagctgacat atattacgat
    20341 agttgacatt taaagtaaat gcttaaatat agatacgaaa ggaaaagtaa aatctgaagt
    20401 gtatttaggt ttaagtaagc ttcttatttt ataaaaaata tgtatgaaag aacagctgat
    20461 ttttaatatt acaaatttag taacggttgt atttgaagct tttgtcatcc atatgttttt
    20521 atcagacttt ttaggccaga aagaagggta tataaaagtt gtaagatatg ctaaactggg
    20581 ttttataata tgtttaggat tctgtaattt aataacttta aaccctaaaa tcacaatgcc
    20641 tttaattttc atccttattt tttcaacatc atttttatat aaaggaaatt taaagacacg
    20701 attgtttact actgttttat taagtatatt ctttatactg tcagaaattg tagttacaag
    20761 tatttttgtt ttatttgtaa aagaaggctt tgaaataatg cttgaaaata atagtataag
    20821 agtattggcg acaattttat ctaaaattgt ctttttgttg acttgtaaaa ttatttgtct
    20881 atttaaaaaa gatgtacatt tagatatgcc cataaagtat tggctccctt tatttttaat
    20941 acctatattt agtttatttc tgtctgtttc tatctttgat gtaagtaaat tttttagtct
    21001 tgaaagttta aaatttctaa gcttaatatc tagtgttggt attttatata ttaattttat
    21061 tgtcttttat ttatttaaat ttattataga taaaactaaa ctatctatga aatatgaact
    21121 acttgaaaaa gaaataattc ataaggaaga attaagactt agtaatgagt gttataaaat
    21181 tattgttgaa cagactgatt ctgtcgtttt cgaatggaat atcaaagaaa ataaatcatt
    21241 tgtgtcgcag gcttggactg aaaaatttgg atataacaat gcatgtaaga atatttttaa
    21301 agaaattaaa gataaagact tagttcattc tgaagataaa gctatatttg aaggttttct
    21361 tgaaagtatt aaaaaaaaga atatgcacaa tcaagcagta tatcgtttaa aaaaatctaa
    21421 tggtgaatat atttggtgta gaacatcaat tacaagcatt tataatgatg aaaatgaact
    21481 tttaagagtt gtaggagtaa ttgtagatgt agatagtgat ataaaaaaat atgaagagtt
    21541 aagaactaga gcagaaagtg actcattgac caatatatac aataaaggta catttgaaaa
    21601 attagtggaa gaaactatag ttatgaatac aggtgataaa aaagatgcat tattcattat
    21661 tgatttggat gattttaaag aaataaatga taattttggt catccatttg gtgattttgt
    21721 actaaaaaca tttgctgata agatacaaac tagttttggt agtaaagact tagtcggaag
    21781 aattggtgga gatgaatttg ttgtatatat gcaagattat gttacagaag taaatttgca
    21841 taaaaaagct aaagaattaa atagagtact ttcggataat tacactgatt tgagttttag
    21901 ttttgatgct tctgtcagta taggtattgc aaggtatcct caagatggaa cttcattttt
    21961 tgaattgttt aaaaatgcag atagagcact ttatagcata aaagcatcag gtaaaaattc
    22021 atattgttta tttgaagaag aactatatgt acagtgaatt tgaatttaga ttttatgtga
    22081 gagtaagatt tatatatact tgtggctgtc tgatttataa aatatgttac tttgtatatt
    22141 tttatatgtt tcagtaaggt taattaacat aagcaaaggt gtaagtaaat ttatattagt
    22201 ttaagtttac ttacaccttt ataaaaatac aaataataga ttcatttaca tttttaaatg
    22261 attaaagctc tttaccttct aaacatgcat aacatatcgt tataattcta gtaaataaga
    22321 ctaaaatgcc cattcctaag attacaattt catcatctat tactccaaat gtttttaaag
    22381 taacttattt cgctttgtat cataataatt tgtctctttt tacattttaa cttctgctga
    22441 gatttgagtt agatattcat tagaatctcg cacacttata tcatatagaa gatattcttc
    22501 ataaacaaaa tccccaatac gtaaattatt ctgattaaaa aaatttaata acttttcata
    22561 agtcttgtaa atagtttcat aactcccttt atgataagca gttacataaa gtccctttgg
    22621 tttgattgat acaggatatt tcttgtactc tttattaact tttgtaaata aatatgaata
    22681 tgattcaaag tctttattaa ttatatcttc acctttaatg attgagccaa tcgtaccata
    22741 atcactcaat tcatagttgt ccataaagtt aatacattca tataaaaaat tttcttcctc
    22801 atctcctaaa aattgttctt tatatgtaac aggtgttttg accaagtact cttcttcatg
    22861 ttcttttaaa gtaatagtat tcgcatctat attacaggca tttttagtga atgaaatagt
    22921 agattccatt agagcttgaa tattatttag tttttcaatt tcatttttaa tatcaatggt
    22981 tttcttttct aaaagctcaa ttagtaaatt aggtgttctt ttgtctatat aagctttaat
    23041 ttcttttaaa ggcattttta cttccctaag tgaagaaatt ataccaaaaa tgctaagttg
    23101 atggtatgag tagtatctat atccattttc tttctttaat tctggtgaga aaagacctat
    23161 atcatcataa tggaaaagtg tttttttatt gattccacaa atctttgcaa attctccagt
    23221 tgtaaaataa ttttttgaaa cttgactcat aattataatt cctccttgac tatcctgtta
    23281 cagtatagtt tatcatagta ttttgtaaag gagtgtgatt atatgaaaaa attaattcat
    23341 tttttaaaac catatagagt tttaattgtt gtagttttga tatttacgtt tttacaaaca
    23401 cttggaactt tgtatatacc aacacttaca gcaaatatag taaacaatgg tgtagtaaag
    23461 ggagatatag attatattgt aaaaacaggt ttaatgatga tgatagtagc tggtataaca
    23521 gctttatcag ctgtgttagt ttgtaaagta tcagcaaatc tttcatctgg attttgtaga
    23581 gatattagag aagcagtatt tataaaatca caagatttat caataaatga ttttaataat
    23641 ataggtacag catcaatgat tactaggagt actagtgata ttactttaat aggtcagtct
    23701 gtgtttatgt ttattcaatt agtattacca gcaccaatta taactgtttc tggtctattc
    23761 ttagcatatt ctatagataa agcaatgaca attattattg ttgtagtaat gtttttattc
    23821 atgctttcag catttttagt tggtaaaaag cttataaagt tgtttaaaat gatgcaaata
    23881 aagatggaca atatgaatag ggtgttacgt gaggtagtaa ctggagtaag agttataaga
    23941 gcttttaata ggagtcgttt tgaaaaaaag agatttgata gaactgcaat agattattct
    24001 gaaatagcaa tttcaataaa taaaatattt gcagtactta tgcctattgt aatgttaata
    24061 atgaatttag gtatagtaag tattatttgg tttggtggga tgagagtcag taatggaaat
    24121 atggaaatag gtcatataat ggcacttgtt gaatattgta tcttaatttt attttattta
    24181 atcatgggag taatggtatt tatgtacata cctagagcag gtgcatgtgc agatagagta
    24241 aatcagatat tagatataga acctgaaatt gtagatggaa atggtaataa agatactgtc
    24301 tcagagagag gacatttagt atttaaaaat gtaacctttt catatgcaca atcagaagaa
    24361 cctgtgttaa ataatataac atttgaagca aaatctggag aagtaactgc aattatagga
    24421 agcactggct caggcaaatc tactattgca aatataatac cacgtttttt tgaaattcaa
    24481 tctggagaaa tatctataaa tggtcaggat attaagaaga ttcctcaaaa agaacttagg
    24541 gataagattg gatttgtacc acaaaaagct tttttattta gtggaacaat agaagaaaat
    24601 ataaggtatg gaaaagaaga tgcaagtatt gaagaagtaa agcatgctgc aagtatagct
    24661 caagctgatg aatttatttc tgatatggaa gacaagtatg actcatttgt agcacaaggt
    24721 ggaaataatt tgtcaggtgg tcaaaaacag agaatatcca ttgcaagagc gttagttaga
    24781 aagcctgaag tatatgtctt tgatgatagt ttttctgcat tagattttaa aacagataaa
    24841 agacttagaa aagcgttgaa aaatgaaatc aaagattcat cagctataat tatagcacaa
    24901 cgtataagta caatcatgga tgctaatcag attatagttt taaatgatgg aaaaattgta
    24961 ggtattggaa aacataaaga tttacttgaa aattgtgaag tttataagca aattgcggat
    25021 tcacaactta gtaaagaaga acttgcataa aatgaagaat taatctgata tttggaggtg
    25081 tatgatatga gtgaaaaaag aatagatgaa caagatatag aagtacttag ttttgaagat
    25141 ggcatgtcag cagaaaaagc taaggatgca aaaaaaacta ctaagagatt attaaaatat
    25201 atggcaaaac aaaagtttaa aatattaatt atttttattt cagtattgat aagttcagcg
    25261 cttacagttt tagcacctat ggttatggga aaagctattg accaactatt taatggaata
    25321 aaaactgcag tccaaacagg tacaaaattc agtgtgaatt ttagtactat gggagggata
    25381 gtatcaatac ttctagggtt gtacttaatt agtgcagtat ttatatatat tcaacagtat
    25441 attatgtcag gagttgcaca aaatctagtt cttagcatga gaaaagattt aagtgataaa
    25501 ctcaataaac ttcctcttaa gtactatgat tctcataaaa agggggaaac acttagtata
    25561 gtaacaaatg atttagaaaa agtagcagat agtttacaag aaggattaat gcaacttatt
    25621 acagcagtag ttacagtagt tggttctatt gtaatgatga taagtataag tgtaccactt
    25681 acaatagtat cagctataac attacttgtt tcattgggta ttactgttgt aattgcaaga
    25741 aaatcacaag aaagattctc tgaaaatcaa aaggcactag gagagttaaa tagcaatata
    25801 gaagagatat ttactggtca aatagtggtt aaagcattta gtaaagaaaa ggatactata
    25861 agaaacttta aaatattaaa tcaaaatctt tataatgcaa gtagaaaagc acagttttcg
    25921 tcatatgcaa tatctccaat tattagattt ataaacctaa ttggctatgt tattatagca
    25981 gttgtaggtg ggatatttgc atcaactgga gcaatgactc ttggtagtat acaagcgttt
    26041 attcaatatg taaatcaagc atcagagcct actacagaaa tatcttatat tgtaaatatg
    26101 cttcaagcag caatagcatc tgcagagaga gtttttacag ttatggacga ggtggaagag
    26161 ataaaggatg aagaatcttc aaaggttatt agcatgccta aaggtaaagt acaatttgag
    26221 catgttaaat ttggatatag tgatgatttt attcttatga aagatattaa tatcaatcta
    26281 aatgcaggag ataagattgc aattgttgga cctacaggag ctggaaagac aactcttgta
    26341 aatttactta tgagatttta tgagatacaa ggtggaagaa ttactattga tggtgttaat
    26401 ataaaagatt taaagcgtgg agaacttaga actatgtttg gtatggttct tcaagataca
    26461 tggctgttta atggaagtat aaaagaaaat attgcatata gtaagtcaga tgccacaatg
    26521 gatgaaattg taagagcagc aaaatcagca agagtagacc attttataag gactttacca
    26581 caagggtatg acactatatt gactgaggat gcttctaatc tatctcaagg tcaaaagcaa
    26641 cttctaacaa ttgccagggc aatactttca gacccatcag tattgattct tgatgaagca
    26701 acatctagtg tagatactag aacagaggta gaaattcaaa aggcaatgaa taacttgatg
    26761 aagggaagaa ctagttttgt tattgcacat agattatcaa ctattcgaga tgctgattta
    26821 atattagtaa tgaaagaagg aactattatt gaacaaggaa gccataagga acttattgaa
    26881 aagaaaggat tctatgaaga actttataac agtcaattta caagtgaata tgatgaagat
    26941 gttgtatgat tatcaagttt taggcaacta aatgattgat aaatattaag ttaaatatag
    27001 taacatgtaa ggttatatgg aataagagta tttctctatt tcatataacc ttttttattt
    27061 atcaaaataa gataaaattt cctttctaaa ttagattgaa gaatgtattt atcaatataa
    27121 aagtaaaata atcattatta ttagtgaagt aaatattgtt tgccacatat atgccataaa
    27181 gatgcactta ttttacggag atttaacaaa gtagtgtaaa gtatactcta aatataaaat
    27241 aaatcaaata gagttaaata aattgagagg tgatataaat agtgaataaa aaattgaact
    27301 atagatttga aatgaagcac aaaataactg aagcagatgt gttagcttta aaatcaagac
    27361 tctatccaat aatgaagaaa gatgaaaatg catctaaaga tggaaaatat cttattagga
    27421 gtttatattt tgatactcct gaagataaag cacttttgga taaattaaat ggcgttgcaa
    27481 taagagaaaa gtttaggata agattttata ataatgactg ctcttatata aggttagaga
    27541 aaaaaatcaa acattacaac atgacatcaa agctatcaac taatttaacc aaaaaagaag
    27601 taataaatat actaaataat gatattgaat ttctaaaaga gtcgacaaat tgtttattaa
    27661 gagaatttta tttgaaatta aaatgtgaaa gattagaggc aaaaagcata gttgattaca
    27721 atagagaagc ttttatttat ccagttggaa atgtaagagt tacaatcgat agtgatatta
    27781 aaacttctgt aaattcggta gatttattta ataaagattt gccaactatt tcggtaattg
    27841 atgagaatat gactgtattg gaggttaaat atgatgaatt tataccagat tttataaagg
    27901 atttaattca aattaataag actacctcta cagcagtttc aaagtatgct tcaagtagat
    27961 tatatattta agaataaagg ctatgattta tataaagata tacataaata aggttaaaaa
    28021 acaaataagt taaaaataaa taaaataaaa aataaataag ttaaaaatag gaaggatgat
    28081 tttaattatg acatttaatg atatttttaa atcaagtttt atagaaaacg tatcaggttt
    28141 ttcatttgtg gacagtgctt tagcactagg ttcagctttt ttagtaggtt tgtttatata
    28201 tatggtctat aaaaagactt atatgggaat tatgtattct cgaccattca atgtgtcgct
    28261 tgtagcactt acaatgctta caacttttgt aatattggcg gttacttcaa atgtagtttt
    28321 atccttaggt atggttggtg ctttatctat agtaagattt agaacagcaa ttaaagaccc
    28381 aatggattta gtatttctat tttggtcatt aggttcaggt atagttttag gagcaggttt
    28441 gattccctta gctgtcatgg gttcaataat tatgggattg attctaatat tcttttcaaa
    28501 taaaacaata tctgaaactc catatatatt gatggtaaat tgtaataatg aagattcaga
    28561 agatatagca actgataaaa ttaaaaaagt atttactaaa tatcaaataa aatcaaaaag
    28621 tgttacacca gaaaaaggaa tagaattagt gtttgaagta agaatgaaag atggagaaac
    28681 aagtcttata aatgacttga gtcaagtaga tggagttact aatgcagttc ttgtaagtta
    28741 taatggtgac tatgtagcat agagaggagt aatcttttat gaaagataaa aaatttaccc
    28801 ttcttatctc gattatgatt atatttttat gtgctgtagt tggagtttat agtacatcta
    28861 gcaacaaaag tgctgattta tatagtgatg tatatattga aaaatatttt aacagagaca
    28921 aggttatgga agttaatata gagatagatg aaagtgactt gaaggatatg aatgaaaatg
    28981 ctataaaaga agaatttaag gttgcaaaag taactgtaga tggagataca tatggaaacg
    29041 taggtataag aactaaagga aattcaagtc ttatatctgt agcaaatagt gatagtgata
    29101 gatacagcta taagattaat tttgataagt ataatactag tcaaagtatg gaagggctta
    29161 ctcaattaaa tcttaataac tgttactctg acccatctta tatgagagag tttttaacat
    29221 atagtatttg cgaggaaatg ggattagcga ctccagaatt tgcatatgct aaagtctcta
    29281 taaatggcga atatcatggt ttgtatttgg cagtagaagg attaaaagag tcttatcttg
    29341 aaaataattt tggtaatgta actggagact tatataagtc agatgaagga agctcgttgc
    29401 aatataaagg agatgaccca gaaagttact caaacttaat cgttgaaagt gataaaaaga
    29461 cagctgattg gtctaaaatc acaaaactat taaaatcttt ggatacaggt gaagatattg
    29521 aaaaatatct tgatgtagat tctgtcctta aaaatatagc aataaataca gctttattaa
    29581 accttgatag ctatcaaggg agttttgccc ataactatta tttatatgag caagatggag
    29641 tattttctat gttaccatgg gattttaata tgtcatttgg tggatttagt ggttttggtg
    29701 gaggtagtca atctatagca attgatgaac ctacgacagg taatttagaa gacagacctc
    29761 tcatatcctc gttattaaaa aatgagacat acaaaacaaa ataccataaa tatctggaag
    29821 agatagtaac aaaataccta gattcagact atttagagaa tatgacaaca aaattgcatg
    29881 acatgatagc atcatatgta aaagaagacc caacagcatt ttatacttat gaagaatttg
    29941 aaaaaaatat aacatcttca attgaagatt ctagtgataa taagggattt ggtaataaag
    30001 ggtttgacaa caataactct aataacagtg attctaataa taattctaat agtgaaaata
    30061 agcgctctgg aaatcaaagt gatgaaaaag aagttaatgc tgaattaaca tcaagcgtag
    30121 tcaaagctaa tacagataat gaaactaaaa ataaaactac aaatgatagt gaaagtaaga
    30181 ataatacaga taaagataaa agtggaaatg ataataatca aaagctagaa ggtcctatgg
    30241 gtaaaggagg taagtcaata ccaggggttt tggaagttgc agaagatatg agtaaaacta
    30301 taaaatctca attaagtgga gaaacttctt cgacaaagca aaactctggt gatgaaagtt
    30361 caagtggaat taaaggtagt gaaaagtttg atgaggatat gagtggtatg ccagaaccac
    30421 ctgagggaat ggatggtaaa atgccaccag gaatgggtaa tatggataag ggagatatga
    30481 atggtaaaaa tggcaatatg aatatggata gaaatcaaga taatccaaga gaagctggag
    30541 gttttggcaa tagaggagga ggctctgtga gtaaaacaac aacatacttc aaattaattt
    30601 taggtggagc ttcaatgata ataatgtcga ttatgttagt tggtgtatca agggtaaaga
    30661 gaagaagatt tataaagtca aaataagatt aaaattgaat ataaataatt ttaatactgt
    30721 taagtctaaa tatttactta gcagtatttt tttagaaaat aatgtatttg gttaataata
    30781 taaggtaata aattgataaa aattaaatac agcatattaa taatacataa taaagtaata
    30841 aaaaaactgt ttaagtataa taacttatat ttagacagtt tttttcattt ataaataata
    30901 taaatgaaat tgaaaacatt tgaaggatag aaattggttg gataaatgta taaattactt
    30961 caccaaaaaa taatgacaaa aattgtaact aagttgtaat aaaatggtag ttatttagca
    31021 taaaataatg tatcatagaa gtatattata aaattaataa aataagattt ttgtaagaaa
    31081 actgctggct tttgatattt agagtgagta gttaaattat gtttaggagg ggtagaattt
    31141 gttgcaaaaa gtattatgga aatttttaaa gctagtagtc ggtttattta tatgttcagt
    31201 tggtatagta ttgacgataa attgtaacct tggattatct ccctgggatg tatttcatca
    31261 aggactttca aatcatatag gaataactat aggaactgct tctataattg taggctctat
    31321 agtagttatt gctgatgtcg ttcttggaga aaatgtagga tggggaactg tttttaacat
    31381 gctactaatt ggatttttta tggatttact tttatatagt aatttaattc cagaggctga
    31441 taatttattt gtaggaataa ttatgttgat attaggattg gttcttttgt ctgttggaat
    31501 ggtattttat atgggaagtg gtttaggaag tggacctaga gatggtttga tggttgcaat
    31561 tcaaaagaaa acaggaaaat cacttaaatt aataagaggt actatagaag ttggagcatt
    31621 aatagtagga tttttattag gtggaaaagt tggtatagga actataataa gtgcatttgg
    31681 attggggtat ttcacacaaa tggtatttgg cttatttaaa ttagattgta gtaagattaa
    31741 acatagattt atagtagatg atataaaatt tatcaaagtg tatatgagtg gtgagaaaaa
    31801 agctgctgtt caaaatatag ttaagtaatt taagaataaa ttcaacgaaa tgttaagtat
    31861 tttaaattaa cattttgttt agatagataa attgaatatt aaaagaatat taaaatatga
    31921 ggattgctag aacactataa aatatagatt tctagcaatt ttttatttgt tcaatatttt
    31981 tttagtacta gaagtcttat tctctattta atgaatgaat taatttataa ttagagatac
    32041 taaactttat agatattaat ataaacacct ttaaactgtg tattttccaa agcctttaaa
    32101 atgcttgtat ttattctaaa taaaaaaata aaaaaatgtc aaaaaaactc ttgtattata
    32161 tccaaatttt atatataatt acctatgttg tttagaaatt ttaaactcaa tgtttagtaa
    32221 acaaaatgtt tagtaaaata aaacagaaac taggaggtgc aacatggata taggtgaaaa
    32281 gataaaaaga ttaagaacag aaaaacaact gacccaggaa gagttagcta atagatgtga
    32341 attgtcaaag ggatttattt ctcaattaga aaataactta acatcaccat ccatagctac
    32401 ccttatagat atacttgaaa tactaggtac aaatttaagg gaatttttta atgaaataga
    32461 tgatgaaaga atcagtttta caaaagaaga tatgtttgaa actgaagatg aagatttaaa
    32521 atataaatta aagtggttaa ttccaaattc acaaaaaaat gaaatggagc caataataat
    32581 aacattgtat ccaggaggac agtataaaga agaaaagcca catgaaggtg aagaatttgg
    32641 atatgtatta gcaggttcaa tatatgtcca tataggcgaa aagaaaaata aagtaaaaaa
    32701 aggagagagt ttttacttta gaccgaaagc aaatcactat atatcaaacg agggcaaaac
    32761 tacagcaaaa gtgatttggg taagtacgcc accatcattt tagaatagag gtgtttaata
    32821 attggtagaa aatataatag aattaaggga tatatctaaa cattatgaag aacttactgt
    32881 tttagataat ttcaatttag atataaagaa aaatgagttt ctaacattac ttggaccaag
    32941 tggatgtgga aaaactacaa cattaaaaat aatagcagga tttgagtatg ctgatgatgg
    33001 taaagtttta tttgaaggta aggagataaa taatttgcca ccatatgaaa gacaagtaaa
    33061 cacagtattt caaaaatatg ctttatttcc acacatggat gtttatgaaa atgtagcttt
    33121 tggattaaaa attaaaaaga ctccaaaaga tgtaatagat gctaaagtaa aagaggtttt
    33181 gaaacttgtt gcactagaag gttttgaaag acgacaagtt gaatcattga gtggaggaca
    33241 acaacaaaga attgcaatag caagagctct agttaatgaa ccaaaggtat tattactaga
    33301 tgaaccactt ggagcacttg atttaaagtt aagacaagag atgcaaatag aattaaagag
    33361 aatccaaaaa aaattaggaa taacatttgt ttttgtaact catgaccaag aagaggctct
    33421 tactatgtca gatactattg ttgtaatgta taagggcaaa attcaacaaa tgggaacacc
    33481 acaagatata tacaatgaac ctaaaaattc atttgtagct aaatttatag gtgaaagtaa
    33541 catatttgat ggaattatga tagaagatta taaagttaat ttctgtaata gagattttga
    33601 gtgtgttgat aaaggattcg aaaaaaacga aaatatagaa gtagtaataa gaccagaaga
    33661 tataaaaatg gtaaagccag aagaaggaat gttaaagggg aaagttacat ctacagtgtt
    33721 taaaggagtg cattacgaga tagaattgaa tgaaaatgga agattgtgga tacttcataa
    33781 tactaaaaat gctgaggttg ggactgaact aggcatggat atatatccag aagatatcca
    33841 tataatgaga aaagagaata actaagatga aaagaaaatc ttttttagca tatccatatg
    33901 tagtttggag tgcgatattt gtaataattc ctttaatatt agtagtattt tttagtttta
    33961 caaaagaatc aggtggaggt tatgccttta cacttgagaa ttataaagaa gtaattgacc
    34021 ctatatatat gaaagttttt gggcgttcta ttcttttagc aggaggagct acattaatat
    34081 gccttatagt tggttatcca gtggcatata taatttcaaa ggctcgtgta agtagaagag
    34141 gttcattaat attattgttt attcttccta tgtggatgaa ctttctttta agaacatatg
    34201 catgggttgc tatattagga aaaaatggac ttttaaatac atttttaggt tggtttggaa
    34261 tacaaccatt agcaattttg tatactaatt ttgctatact tttaggtatg gtgtataact
    34321 ttttaccatt tatggttctt ccaatatata cagcactatc aaagatggat aatgatttga
    34381 taaacgctgc tcatgacttg ggtgcaaata atatgacagt ttttagaaaa attatatttc
    34441 ctttgagttt gccaggtgta atgtctggaa taactatggt atttatgcca gcagtcacta
    34501 cttttgcaat atcaagactg ttaggtggag gtaaaataat gctggttgga gatttgattg
    34561 aacaacagtt tacagttgtt ggagattgga actttggttc agctatatcg atatttatga
    34621 tgatagtaat attaatatct atgtctataa tgtcaaaatt tggagatgaa tctgacaaag
    34681 aaggcggtgg gttactattt taaaattaaa gaaaataact tctaatatat atttagcatt
    34741 agtattctta tttttgtatg cacccatatt tgctttggta ctattttctt tcaatgattc
    34801 aaaatcaatg gcaagatgga atggatttac atggaagtgg tatggtcaat tacttcaaaa
    34861 tgagagtata atgagtgctt tatattatac tattgtaata gctatattag cgtctgtaat
    34921 atctacaata gtaggaacta taagtgctat aggaatacat aagatgagag gtaagagtaa
    34981 gaaattaata ctaaatgtaa actatcttcc tattttaaat acagagatag ttacagcagt
    35041 agctcttatg agtctgtttg tatttgtaaa aatggaattt ggatttacaa caatgctatt
    35101 ggcacatata atgttttgtt tgccatacgt tatactttca gttttgccaa aaatgaagca
    35161 attacctgat aatatagaag atgcagctat ggacttggga gcaacaccta tatacgctct
    35221 tagaaaagta attttaccac aaataaaacc aggtatagtt tctggatttt taattgcatt
    35281 tactatgtca atagatgact ttataataag tttctttaat gctggaaatg gtgtaagcaa
    35341 tctttctata gaaatctatg gaatggctag aagaggtata aaacctgaaa taaatgcatt
    35401 atcaacaata atgtttgcag tggttctagg tttactttta ctggctaata aaaaagaatc
    35461 tatagtaagg gggattaaat aatgattaag tttaaaaaag caatatccct tatagctgta
    35521 ggtatgatga cagttacttt atttacagga tgtaataaag caactgattc tacaaaagtt
    35581 ttaaatgtat ataatgttgg agattatata gatgagtctc ttatagataa gtttgaaaaa
    35641 gaaacaggaa tagatgttca atattcaact tatgatacta atgaaatgat gtatcaaaaa
    35701 gtaaagagtg gtagtacaca ctatgattta gtatttcctt cagactatat ggtagagaaa
    35761 atgaaaaatg aaggtctttt ggaaaaatta gattttaaga atatacctaa tatgaaatat
    35821 ttagataaga gttttttaaa tcctgtatac gacaaaacta atgaatatag tgttgcatat
    35881 atgtggggaa ctcttggaat actgtacaat aagaaagaag ttaaagaccc tatggatagc
    35941 tggaatatac tttggaatcc aaagtataag ggaaatataa tgatgtttga ctctgttaga
    36001 gatactatag ggataactct taaaaaatta ggatatagca tgaatagtgt aaatccaaaa
    36061 gaaataaatg aagctaaaaa tcttttaatg aaacaaaagg atttagtatt ggcttatgta
    36121 aatgatgaag gtaaggatag attgcttggt ggagaagtgg caatgggtat gctgtattct
    36181 ggagatgcag ttacactaat ggagcaaaat cctgaccttg attatgctat acctaaagag
    36241 ggaactaata aatgggtaga tgctatgtgt gtacctacaa cagcacaaaa taagaaagaa
    36301 gctgagctgt ttataaactt tttattagac ccagagaatg caaaagtaaa tgctgagtac
    36361 attgggtatt caacacctaa tacaggagca ctaaaattat tagacccaga aataactcag
    36421 aatcctgttg catatccatc taaagaagta cttgataaat gtgaaacttt tgaagatatt
    36481 ggtgaaaata taaaattata tgacaaggct tggatagagt taaaatcaaa atagggtctt
    36541 gttgttttaa gtaaatttac ttaataaata cttaataaaa ctgttctttt ttagaaaatt
    36601 tattttctaa ttattgaaca gttttatttt ttgtttaagt tatattcata tgcaatttaa
    36661 atagtttatt aataaatgaa aacttatttg tataatgact ttaataataa ttagaaaaaa
    36721 tgggcaactt aatagaataa ttggaggtgt aaatttataa aaaatgaata ggataaataa
    36781 aaaaatagat ttattaatat tggctttgct cgtttttata tttttaattg ttggaatagt
    36841 aatactatcg attaggacag aaaataaatt gaatgtgttc ataatgttag caataatttt
    36901 ttttataata atgttaactt atttatcaaa ttcagtagtg gggttgataa caagttcaat
    36961 aattatattt atgtatacat cctatatttt atataacaat attactcaca atatggatgt
    37021 tgaatttata tcatatatgt ggataatagc aacaccagta tcttcaatta taatgggtaa
    37081 tctgaacaaa agcataaatg aattgcaaaa tacaaataaa aaactatctg aacagtataa
    37141 ggaattagtg actattgata gtgaaactgg acttagaaat ttaaagattt tttataatga
    37201 tgtaaatatg gagataagta aatctattag acataatact gatttttctc ttatgatagt
    37261 aaaattacca tactacggaa acctacagac tatatttggt gaaaacaaaa ctaataaaat
    37321 agtaaaatat attggttcaa atattataga atgtacaaga aatgaagata taatttatag
    37381 tttacaaaaa gatatgatag ggatactaat gccaaataca tctttggaag gttcaaaagt
    37441 tgttaaagac agaataaaga aaaggataaa agaattaaac ttagatttaa acaatagggg
    37501 aaaatatgta aatatagatg tcaaaattgc atttttacaa tataagagta gttttggaga
    37561 tagtataaat tttaagaata tagttgaaga ggaacttcaa tatgatgttt aaaatattta
    37621 ataaaagtct attaaaatta gtagttgtat tatcaatagt actgacaata tcaaatttta
    37681 gcttatcttc atacgcatca gaaattactt ccagcacaga taaggtatta atcatatatg
    37741 attctaagaa agaaacagct tataatagag atattttaaa tattatgagg actctattgg
    37801 gaagatttag ttcagatata gagctattaa aattgagtaa ctatgatggt gagataaata
    37861 aaaattatta cagtcatata tttactttag gaatcaatga aaactcatat aataatgata
    37921 aaaacactaa aaacttgatt agttccttaa attcatataa aggaactata tgttggttag
    37981 gatatggtat agaaaatctt ttggaacata aaaaatacaa tttagactat gtaggaaaaa
    38041 caaacaatat agttagtgta aattatagag gtaaatcata taacttggat gaacattatg
    38101 tttttaacat tgtagaatca aaagatacaa gtaataaagt aataggaagt attaatgata
    38161 ccttaaataa gtatccatat ataataaatg ataaaaatct tttttatgta tcaaaattag
    38221 atttagatgg agttttattt tatatatttt gcgattcact taatgatatt tttaatatta
    38281 agacgtttga taaaggacgt atatttgtaa gaatagaaga tgtacatgct tttagagaac
    38341 caaaaaatct tgtagagata gcggattatt taagtagtaa gaatatacca tttacgattg
    38401 cattaatacc agcatatgta aatcctaaaa atcataaagt aataacttta tcagaaagcc
    38461 ctgaaattgt caaagcaata aaatatatgc aagataaagg tggaactgtg atattgcatg
    38521 gatatactca tcaatacaag aaagaagacg tttctggaga agggtatgaa ttttgggatg
    38581 gtaaaaaaga tgaaccctta aaagaaaata tgaagatatt tgtcaaagat agagttttga
    38641 atggtcttag agtatgtata gagaatggaa tttatcctct tgcatttgaa gcgccacatt
    38701 atgcaatgga atcagaggga tataaagaat taaaaaaata tttttctact tatatggggc
    38761 aacatcaaaa taatgataaa aaatttagca caaatacata tccttatatt attagggata
    38821 cagaagagtt taatatattt atacccgaaa atttaggata tatagaccca gaagataagt
    38881 ttacttttca aaatataaaa gaaaatttag ataaattatc cattgtaaga ggttttagtg
    38941 gagggttctt ctttcattca tatttaaaca tagagtatct aaaaaacaca atagaatatt
    39001 tagaaaaaca gaatatagaa tttatgaatt taagagattt taataattgg gtaaaagttg
    39061 atgaaataca aataagaaat aatggagatg aaattatagt caactatgat aaggacttag
    39121 atgaaataac taaaggtgat actagattta aatccatatc caatattagt aaaattctaa
    39181 tattcatagt atctataagt gttttaatat ttgtgattat atttatatat tttaagagaa
    39241 tagataaaaa gaaattttta aaataaatga ttttatatta gaatcaatat tttaaaatat
    39301 tttaggagaa atttatgaga gatttaaatg tatcagagta tttgttcgta tttagtttgt
    39361 ttagtatatg gtctttattg cttataaata ttattttagc tatgggtgga tatatatttt
    39421 attttaaaaa ctttgataaa gaaataaaag aaattgatga atatcctatg atatcaatac
    39481 ttgttcctgc tcataatgaa gctaaagtga taggtagaac tgtggagtct ttgctattac
    39541 tcaattatcc taagagtaag atggaactta ttgttataaa tgacaattct tctgataata
    39601 gtaaagaaat tttagaaaat ataaaggata ggtacaacaa ttataatttc actataataa
    39661 atacagatag tttaacaggt ggaaaaggaa agtctaatgc attaaatatt ggatatacga
    39721 tttcaaaagg agattttata gctgtttatg atgcagataa cacaccagat aaaaatgcac
    39781 ttagatatct agtacaaact atagtaatga atgatgaatt aggtgctgtt attgggaaat
    39841 ttaggactcg aaataaaaat aaaaacctat taaccaaatt tataaacata gaaacattaa
    39901 gctttcaatg gatgtcacaa gctggtagat ggcaactttt taatctatgt acaataccag
    39961 gaactaactt tatattgagg agaagtatca tagaagaaat tggaggatgg gatagtaaag
    40021 caattgcaga agatacagaa ataagtttta ggatatataa attgggatac aagataaagc
    40081 ttgtaccaca atctataaca tgggaacaag agccagaaac tgttaaggtg tggataaagc
    40141 aacgtactag atgggcaaaa gggaatatat atgtattaat gaaatatata aaaaatatat
    40201 ttaaacaggg aagaaataag attgtgtttg atatagctta ctttttttct gtatattttc
    40261 tatttttaac atctgtaatt atatccgata ttttatttgt tttaagtata tctaaactag
    40321 tagaaatttc tattccaatt aacttttttc taatatggat actatcttat cttttattta
    40381 ttatagaagt gagtataagc cttactatag aaaaaggtga agcaacaatt gaaaatatat
    40441 ttatagttgc aataatgtat tttacatact ctcaactatg gctgtttgta gctataaaag
    40501 gaatgataga gtatctaaaa gatataattt ttaaaagaga ggttaaatgg tataaaacag
    40561 aaagattttg attcatgtac aggaggaatt aacatgaaaa aatttattat atcaattata
    40621 tctttagtat tgtttttttc aaatatatca attatataca aagtaaatgc tgatgagact
    40681 aaagttaaaa attataagtt tgaaagagat ataactattg atggtgttat aggaagtaat
    40741 agtacttttt ttgaagtaaa taaaaattgg gatattgaag aagttttatt gcatcttaat
    40801 tttagtaaga gccaaatatt aaatggagat gtttcaagtt taactgtatt gataaataat
    40861 gtaccaataa aatctattaa attaaatgct aagacaaatt ataaaaatac actagaagta
    40921 ttagttccaa aagattatat aattcaagga tataatgaaa taaaaataaa aacatacaaa
    40981 acaatatctg ataaaatttg ccaagatgat tccaatactg ggaactggat ggttattcac
    41041 aaagaatcat atatatcaat tagatataag cagaaaaagg tggaaaactc aataaatgaa
    41101 tatccgtatc catatgcaga aattgaaaat aatcataaat tagatacaac tatagtagta
    41161 ccagataata tgactagagg agagactaca gcagtgttta atttggcatc agcatttgga
    41221 aaaataacaa aaaatgatga tttaaagtta gatgttaaat tatattcaga aatgaaaaat
    41281 tggtcagatg ataatattat atatattggt aaacctgaaa atacagcaga agaaattttg
    41341 gatattttaa gtataaagga acaaacccta ttatcttcaa actgtataat caagcaagta
    41401 gattcaccat acaataagaa taagaagatg atggtggtaa ttggtagtaa tgaagatgat
    41461 ttaataaagg catcaaattt attaatagaa aatagacttt ctaatcaagt tttatcatca
    41521 tcagtacttg taaacaaaga gactaatata aaaattaata gggaacaaaa attaaattta
    41581 ggtcatttaa cattaaaaga cttaggatat tctgactttt tgttggaagg agcatttaat
    41641 caacaagctt tgtttgatgt caaaatacca acgggtaagg tattagatga tggttcaaag
    41701 attatcttaa atttaagata ttctgacaat ttagattttg aaaaatcttt agttacagtg
    41761 tctataaatg atgttattgt gggaagtaaa aaattggata ggtcacattc taataatgat
    41821 aagttagaat taaaaatacc taaagatata gataataaaa actattatca agttaaattg
    41881 acatttaatt tgagtataaa aaattcgaat tgtgttacta gagagagtaa taatccttgg
    41941 gcatatgtat caaataattc ttatttggcg ttatctacga aagaaaatga aaccttatct
    42001 tttgaaaatt atccgtatcc atttgttaga gatgatgaat ttaatgattt aactgtgata
    42061 atgccagatt attcagggtc acaagctatg acctggatgt ttagattagg tgttacttta
    42121 ggtgcgaata taaattcaca taatggaaat ataaatgtaa ttagaggaaa agaatttagt
    42181 gacaagtata aggatactaa tattgtagtt tttggagtgc cacataataa ttctgttata
    42241 aagatgttaa ataataattt aaatataaag ttcgataaaa attactccaa ttttatatca
    42301 aatgataaga taagctttat tgatgattat ggaaaaaata tttctaccat tcaattaata
    42361 aaatcaccat ataataatca aaaaaatatc atggtaatta gttcaatgaa tgaaaaaaac
    42421 ttatatttag gaatggatta tttgttgaat aaaagtaaag ttaatgattt aaaaggagat
    42481 acattgataa ttgatgaata cggagaggca gaagatttag cttataattt aaaatctaag
    42541 aaagaagtaa aagattcaag ttggaatatg agtataaata agacaactaa agtattttta
    42601 atgatttctt ttattactat aattgta
//
LOCUS       DAEQAF010000025        42090 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.026, whole genome shotgun sequence.
ACCESSION   DAEQAF010000025 DAEQAF010000000
VERSION     DAEQAF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42090
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.026"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(148..717)
                     /locus_tag="KRN00_001432"
     CDS             complement(148..717)
                     /locus_tag="KRN00_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBH1827299.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            920..1147
                     /locus_tag="KRN00_001433"
     CDS             920..1147
                     /locus_tag="KRN00_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1827300.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(1366..2109)
                     /locus_tag="KRN00_001434"
     CDS             complement(1366..2109)
                     /locus_tag="KRN00_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBH1827301.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            2277..3149
                     /locus_tag="KRN00_001435"
     CDS             2277..3149
                     /locus_tag="KRN00_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1827302.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            3149..3814
                     /locus_tag="KRN00_001436"
     CDS             3149..3814
                     /locus_tag="KRN00_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1827303.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTFKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            3835..4692
                     /locus_tag="KRN00_001437"
     CDS             3835..4692
                     /locus_tag="KRN00_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1827304.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(4848..7394)
                     /locus_tag="KRN00_001438"
     CDS             complement(4848..7394)
                     /locus_tag="KRN00_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1827305.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(7394..8080)
                     /locus_tag="KRN00_001439"
     CDS             complement(7394..8080)
                     /locus_tag="KRN00_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827306.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(8163..9152)
                     /locus_tag="KRN00_001440"
     CDS             complement(8163..9152)
                     /locus_tag="KRN00_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1827307.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSSTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(9139..9825)
                     /locus_tag="KRN00_001441"
     CDS             complement(9139..9825)
                     /locus_tag="KRN00_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827308.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(10325..13531)
                     /gene="carB"
                     /locus_tag="KRN00_001442"
     CDS             complement(10325..13531)
                     /gene="carB"
                     /locus_tag="KRN00_001442"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH1827309.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRIEEPRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKMRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(13724..14773)
                     /gene="carA"
                     /locus_tag="KRN00_001443"
     CDS             complement(13724..14773)
                     /gene="carA"
                     /locus_tag="KRN00_001443"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH1827310.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(15031..18237)
                     /gene="carB"
                     /locus_tag="KRN00_001444"
     CDS             complement(15031..18237)
                     /gene="carB"
                     /locus_tag="KRN00_001444"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBH1827311.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKENCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(18290..19333)
                     /gene="carA"
                     /locus_tag="KRN00_001445"
     CDS             complement(18290..19333)
                     /gene="carA"
                     /locus_tag="KRN00_001445"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBH1827312.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGPGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(19359..20075)
                     /gene="pyrF"
                     /locus_tag="KRN00_001446"
     CDS             complement(19359..20075)
                     /gene="pyrF"
                     /locus_tag="KRN00_001446"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBH1827313.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVKEIENA"
     gene            complement(20451..21086)
                     /locus_tag="KRN00_001447"
     CDS             complement(20451..21086)
                     /locus_tag="KRN00_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBH1827314.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAGGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(21110..22024)
                     /locus_tag="KRN00_001448"
     CDS             complement(21110..22024)
                     /locus_tag="KRN00_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827315.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            22624..23853
                     /locus_tag="KRN00_001449"
     CDS             22624..23853
                     /locus_tag="KRN00_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1827316.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(24058..26439)
                     /locus_tag="KRN00_001450"
     CDS             complement(24058..26439)
                     /locus_tag="KRN00_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBH1827317.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPIVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(26411..27136)
                     /locus_tag="KRN00_001451"
     CDS             complement(26411..27136)
                     /locus_tag="KRN00_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBH1827318.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(27126..27581)
                     /locus_tag="KRN00_001452"
     CDS             complement(27126..27581)
                     /locus_tag="KRN00_001452"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBH1827319.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(27863..29044)
                     /locus_tag="KRN00_001453"
     CDS             complement(27863..29044)
                     /locus_tag="KRN00_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH1827320.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYFNSGI
                     SVINQLVYQLRDLRSLIGESLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTMFEVQLPIIQS
                     A"
     gene            complement(29034..29726)
                     /locus_tag="KRN00_001454"
     CDS             complement(29034..29726)
                     /locus_tag="KRN00_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827321.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(29860..30576)
                     /locus_tag="KRN00_001455"
     CDS             complement(29860..30576)
                     /locus_tag="KRN00_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1827322.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDNDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            30701..31435
                     /locus_tag="KRN00_001456"
     CDS             30701..31435
                     /locus_tag="KRN00_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine biosynthesis protein TtcA"
                     /protein_id="HBH1827323.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMIYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(31720..32571)
                     /locus_tag="KRN00_001457"
     CDS             complement(31720..32571)
                     /locus_tag="KRN00_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1827324.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDTIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDKLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(32597..33535)
                     /locus_tag="KRN00_001458"
     CDS             complement(32597..33535)
                     /locus_tag="KRN00_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1827325.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(33638..34288)
                     /locus_tag="KRN00_001459"
     CDS             complement(33638..34288)
                     /locus_tag="KRN00_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1827326.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(34437..34625)
                     /locus_tag="KRN00_001460"
     CDS             complement(34437..34625)
                     /locus_tag="KRN00_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBH1827327.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(34732..35916)
                     /locus_tag="KRN00_001461"
     CDS             complement(34732..35916)
                     /locus_tag="KRN00_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1827328.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTSLDVINFDKVESVVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCYGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(36058..36975)
                     /locus_tag="KRN00_001462"
     CDS             complement(36058..36975)
                     /locus_tag="KRN00_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBH1827329.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTEEEAEQQILNCFLK"
     gene            complement(36997..37725)
                     /locus_tag="KRN00_001463"
     CDS             complement(36997..37725)
                     /locus_tag="KRN00_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1827330.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(37921..38121)
                     /locus_tag="KRN00_001464"
     CDS             complement(37921..38121)
                     /locus_tag="KRN00_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827331.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(38246..38626)
                     /locus_tag="KRN00_001465"
     CDS             complement(38246..38626)
                     /locus_tag="KRN00_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1827332.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMDPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(38899..40257)
                     /locus_tag="KRN00_001466"
     CDS             complement(38899..40257)
                     /locus_tag="KRN00_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1827333.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            40705..41157
                     /locus_tag="KRN00_001467"
     CDS             40705..41157
                     /locus_tag="KRN00_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HBH1827334.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(41314..41931)
                     /locus_tag="KRN00_001468"
     CDS             complement(41314..41931)
                     /locus_tag="KRN00_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBH1827335.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
BASE COUNT        13448 a         7483 c         4817 g        16342 t
ORIGIN      
        1 tatactctta aaataaaatt atataattaa aaatactcta taaaagctaa aaagtttttc
       61 tattcgctac atctaaaaat aattagatag aggtataaat gtatttagtt tatttatacc
      121 tctagtcttt tataaattat atctctacta aattgatttt ttagcacgaa taagtgtgct
      181 cttggagata ccagtcatct tcacaacctc tctatatggc ttagaattta ataaccccaa
      241 tgcatattgt atctgttgat tgctgtattt ctttggccta ccatctttaa agtccttttt
      301 ctttttagca aattcttttc ctaattgagt acgttctatt atcatatttc tctcaagttc
      361 tgcaactgca agtaatgtag tcaaaaagaa tttacccatt gaagtatttt ctaaaagacc
      421 tatatttaaa atatgaacac ttacttcttt agcaaataaa ccttctatta gttgtattcc
      481 ttctgatgta cttctagcta gtctatccag cttagttgca acaagtaagt ctcccttttt
      541 tagagatgat ataatttttt caaatttagg cctgtttgta gtagtgcctg tataagtttc
      601 ctttattatt ttagcatcat tatatttatt caaaatttct tgctgttgct gatacaaact
      661 gttgttgtct gtttgatttt ttgtacttac acggcaatat ccatatataa taatcatcac
      721 ttcctaacat aaagattttg tacagaagtt acccagaagc ttgtttttac ttatctttat
      781 ccattttact aaaacgattt ttgggtgtca atactgttaa cttttgacac cataataatt
      841 cctttataat ttgtttgact atgtcaaaaa ttaccaatat aatgaaatta atgagtttat
      901 acaaattgga ggaaataata tgaatagtct gttaaaagaa gcaatagatg aattaaaaaa
      961 catccattgc ggggaagttt ttttattaaa agaattgttc aaaggctatg aatggaacag
     1021 gttggagatg aatatcagat tgaaattagg aaaacttttt ttgtatgaag tggtaactaa
     1081 tcccaattta aatgtagagg tcatcaataa aaattctgct tatcagcaaa tgtataaaaa
     1141 aaaatagtga cttaaatgta tataatagta taatcttctt attgattcaa aagttaaaac
     1201 ttttaataca aaacaatcat tctattttaa catttatcaa tatgtctaaa tttatataat
     1261 taacacatac gaatagtatt gtttaaatca cattatttaa gatagataaa tcttaaccct
     1321 actccagcat aaatactaaa atagggctta gaattatcta tatttttatc ccataaaatg
     1381 cttagctctt cctcttgatt gaacatatat atctggggaa atacaataga agcgtaaatt
     1441 tataaaattt ccaaagtcag aaaacttcag ttcaaactta ggtataccaa aactttcagg
     1501 tgctatttcg tcaacaccaa aatagatgat aattccatta tctgtaagat aaaatgcttg
     1561 gtcttcaggt ataactaact caacattaga ataatacatt tctctatttt catttatttg
     1621 agatttaatg taatcagtaa ttatattaat ataatcaact ccatctctaa aaatgtcatt
     1681 aagtaaaagt tcttttccag ttgtcaaatc tatattgtaa ttattcaatg tattgtattt
     1741 aggcccatag ttattagcaa accccataag atttaatatc atactcagta cataattttt
     1801 attaaaagta actgcgtaac tggtagatac ccaatagctt tgttttggaa gtgaattttg
     1861 agaagctgcg ttattatatt ctcgttcttc ttcctgtaag ccatttttaa aattatttac
     1921 agtcattctt acagcattgt ttatgttatt taaaataact gggtttacat acgtggattg
     1981 atttctaata ttgtatataa caggatactt tacatcatat gaaaaatact tacttctttc
     2041 aaaatcttca ttaaattgta catataatat attatatgta caggtatttg tagattgata
     2101 attttccatt aaaatcctcc cccttttata aaaaaatcag atacaatata atatgcttaa
     2161 aacagtaata atgttaatgg taaatgtaaa gaatagaaag tatctaaaac agcaaaaaat
     2221 gactaatttt gtggtataat acataggatt gagagttatt ttataggagg aaaaatatgt
     2281 tattattagc agataaatgg aaagattatg aacttataga tatgggaaat ggagaaaaat
     2341 tagaacgttg gggaagttat gtacttagaa gaccagaccc acaggttgta tggccaatgg
     2401 aatctgaatg ggctttatgg aaaaaccctc atggacatta tcacagaagc aataaaggtg
     2461 gaggtcaatg ggaacacaaa aaaagatatc cagaacaatg gactataaat tataaaaact
     2521 taaagtttca cattaaacca actggcttta aacatactgg attattccca gagcaagcag
     2581 ctaactggga ttggatgata gagaaaataa agaaagctaa cagacctata aaagtgttga
     2641 atctttttgc atatacaggt ggagctactg tagcatgtgc atctgctggt gcagaagtat
     2701 gtcatgttga tgctgcaaaa ggtatggtta attgggcaaa agaaaatata gaattatcag
     2761 gtcttaaaaa tcaaacagta agatttatag tggatgatgt tgtaaagttt gttgaaagag
     2821 aaataagaag aggtaaaaaa tatgatgcaa taataatgga ccctccttct tatggaagag
     2881 gtcctaaagg agaagtatgg caaatagaag aaaagttata cagttttgta gatttatgta
     2941 tgggagtttt atcagataac cctttatttt tcttaattaa ttcttataca acaggatttt
     3001 ctccaatagt tcttgaaaat gtattgtcta caacaatagg taaaaagaca aatacaggag
     3061 atatatacgg tggggaatta ggaataccag cttccagaga tggtaagata cttccttgtg
     3121 gtatatttgg aagatgggag aaaaaataat gataaaagtc atatatgaag ataaccattt
     3181 attagttgta gaaaaaccag ttaacatatt gtctcaagga gataatacta atgataaaga
     3241 tatggtaaat cttttaaaag actatattaa aaaaaagtat aacaaacctg gaaatgtata
     3301 tattggttta atacatagat tggatagacc agtaggtgga gttatggtgt ttgcaaaaac
     3361 atcaaaagca gcatctagat tgtctgagca ggtaagaagt aagactttca aaaaaactta
     3421 tctagctgtt gttcatggta agataaaatc taactcagat atactaaaag attttttata
     3481 taaaaataaa aaaactaata tggtaactgt agtgaaaaaa agccataaag atgccaaaga
     3541 agctgaactt aactataatg tattagattt taaagaaaat ctaagtttag ttcaagttaa
     3601 tttaaagact ggtcgttctc atcaaataag agttcaattt gcaagcagaa aacatccatt
     3661 atacggagac caaagatatg gcaaagaaat aaataagatt ggacaacaaa tatctctttg
     3721 gtccaataag atagaaattt gccatcctac tacaaaagaa aaaatggaat ttacatgtca
     3781 tccacctgac aaatatccat ggaatatatt ttaaatctca aatgaggtga ttatatgagt
     3841 aaaaaatttt caataggaga aatgtctaaa cttcataaaa taagcataca gacactaagg
     3901 tactatgacc aaatagattt atttaaacct gttcatgttg accaagaaag caattacaga
     3961 tattactcaa ttgaccaatt ttcacaatta gatattataa aatatttaaa atatttaggt
     4021 atgcctttaa aagaaattaa gtcaaagctt gatgaaaata atgaagaaat tctaaaatta
     4081 ctaacaaata aaattaatat agtggatgaa aaaattaaag aattagagct tataaagaag
     4141 gtactaagca caaagaaaga aactatggaa aaaggtatga aagtagatga agttggtaaa
     4201 atagtgagaa aacatattcc acgaagaagt atcttatcta tagagtatga agaaggatta
     4261 agtagtgaag aaactatgga actttccaga agacaaatag caaatatatt agaagataat
     4321 atatctgtgt tctatggtgg agtaagtgga cttgtatcta tagataaatt tttaaaagaa
     4381 gataaagtta tttatgacaa tagttttgtt actgttgaaa gagacttatt tgatataaaa
     4441 tcacaaaaac atataacaga aatttcatct ggtgatttta tttgtatgac atataaaggg
     4501 ccttacaaag aaaattatac cgcttttaag aaactggttg attatgttga atataaaaga
     4561 atacctattg aaaattatat atatgaaata cctataatag accctctgtc tacaaacaac
     4621 gaagaggaac ttctaacaga aattcaaata caagttaaaa agagagaaat tgacttaaga
     4681 tgtctagtgt agtaatctag tttacttaca catcttaata tagttgtcta ttatcaacat
     4741 atgatttttc tagatagtga ttcctaacag tgagattttc aaaaaatagg aggaaatatg
     4801 gctaatgcta attccctcct atttttaatt aagccatatc attttaatta agccatgtca
     4861 tcacgaagtg catcaataat attttctttt tttatcttat taatagtata caacattgta
     4921 ataaatacta taaataaaac actaaatata ctaattccaa tactaaacca tggaatcaca
     4981 aaatcaatat catctgtaac cattacttta tgaattagcc atgaagaaat tactgctata
     5041 ggaagtccaa agaacaatgc tctcatgcca taaaaggcac actcaaaatt catcatcttt
     5101 tggaaatcat gctcagacat tcctacagag cgaagcatgg caagttctct acgacgtaac
     5161 ttaatattag ttgaaattgt attaaacaca ttggcaatcg aaatcagaga aatcataatt
     5221 atgaaagtat aagcaaaaac attggcaata aaaatgtaat tacggttctc atccatcatt
     5281 ccatacatat tgtacagatt gtactcattc gtaactccct cactctcaat aatttgctcc
     5341 atttctgcaa ctgactgagt aggatttttc gattgaaagc ttaaactttc aattcctgta
     5401 gaaacaccag gaatctcaaa cttatctttg gctgaataag gagccaatac tctgaagctt
     5461 gctttcttca catctgaact tctgattcct ggaggagaat caggtggcac tactttgaca
     5521 aatgaaatat tcacattttg tctctcaggt atctccaact tgccattagt ttcaggagtg
     5581 aggctaacat tcatagaaga actgttgaaa atatcaataa tattattatc ctttgttacc
     5641 atagaaacag caatcagttt tgcattttgt ccagtatatt cttctgctgg taatccaaga
     5701 cttttaataa tattcagata agttctatca tcaagaaatt gcatatctac tggtaattca
     5761 agcatttcac tcatagaatg tgaaccctca tagttcaaat aatcgtctgt aagctcactt
     5821 actttggcaa cacatgaata ggtcataagt ttctgataca aaccttcgta aacaccattt
     5881 gcagttttta gcttatcgta aagcttcaac atttcgttgt ctttcatacc ttgtgtagaa
     5941 aaaataatat cctggtcagt aacctctgac ctctgatttg acatctgttt taggtctgct
     6001 actaaagcac ttgtagatat aaatagaact atgcttaaaa caagcgacaa tacaatactt
     6061 cgataacgtt tcttgtttct tttaaagttt ttcatagcaa gaactccctc aagaccataa
     6121 actcgctgtg ttagttttga tgtcttcaca gatttagatt caatttttac ctcatttgtc
     6181 tgacgaatac actccatcac tggtgtgttg gcagcctttc ttgctggtat gtaagcagaa
     6241 attaagattg taaccatact taccactgct gcaacgatga ttgcagggat agacaatgtt
     6301 aatgtcaacg gaacgtttac atagagaata tttgcaaagt ttttagctat gacagaaatc
     6361 acaagtccaa tactgactat accgattgca acaccaattg gtataccaat cgcaccaatg
     6421 caaattcctt caaatagcac cgaatttcgt aactgttttg ctgtagctcc aacagatgaa
     6481 agtattccaa attgatgtgt tcgctcgttc aatgacatgt taaatgaatt atatattaga
     6541 aaaattgagc ctagcatgat tatggcaagc acaatgccac caaccgagta caaaaacata
     6601 ttgaacaaat tgttatcaga aacacctatg aagcgcaaca cattgtcatt gaaaatggaa
     6661 gcatggtctt tagtgctact tatgtaagag cgaatctgat gtggattttt caatgtgaca
     6721 aaaaggctaa gactgtcagt cttgacttgt ttatcttctt tggttatcaa ggtatatcct
     6781 ggtgcagaag attcttcaaa tacgggcttt ctacagatac ccacaactgt ataagttttc
     6841 ttatcctgtg gcacaaaaac ttcactccca gcagtgtatg ggtcactctg accaagcttt
     6901 tcattttcac tcattcgttt ccctacatcc aaagaaatag tatcacctac tgcaaatttg
     6961 acaccaccat ctgtcgcaac tttacttgaa acaagaatct ctctactatt ttcaggtaat
     7021 cttccagaaa ttaaagttat aggcaaagta tcaaaagctt ctttgctaaa tccagcaata
     7081 aaaagatatg gtttatctgg atttctgtta ccttcaagtg ttgcatagcc aatattttca
     7141 aatgttgcag tatttgcaac ttcatcattg actctttgtt cctgtacaaa agaagaatcc
     7201 acatccaaaa actggacatg ccaatcacca tattttataa tagctccatt tgtcatatag
     7261 ttcatcaaag aaactccaaa ggtagtaact gctgtaatca tagcagctga cagaacaact
     7321 cctataattg ttacaagagt tcgagtgcga ttctttttca atccttgcag agcaactttg
     7381 ttaaaaatgt tcattaacga ttcaccttcc tctcatcacg cactactttt ccatctgaaa
     7441 tacagataat tctatctgcc tgtaaagcaa tgttttcatc atgtgtgaca ataatgagag
     7501 tttggtgata tttactatgg ctctctttca gtaactggat aatctcttgt ccatttttac
     7561 tgtctaagct acctgtaggc tcatcagcaa gcataactgc tggtgcattc atcaatgcac
     7621 gaccaatggc aacacgttgc tgttggccac cagaaagttg atttggtaaa tgtgtttttc
     7681 gttcttttaa accaagcaat tctaacaagt catttaaccg ttcttgattg accttacgct
     7741 tatccataag tataggcaat gtgatatttt ctactacatt taatgtgggt atcagattgt
     7801 gaaactgata aatcaatcca acttgtcgcc tacgaaaaat agcaagtttt tcattgcttt
     7861 ggccatatac atcttgcccc tccagatata tctttccact tgttggtacg tctactcctg
     7921 caatggaatg tagtagtgta gatttaccag aaccagaaga accaatgatt gcagtaaact
     7981 ctcctttttc aatagtaagt gagacatggt caagtgcagt aaccttattt tcattcttac
     8041 cataaacctt acataaatct tcaatcttta aaaacgccat tatataagtc tcctttcata
     8101 ttttataaat atatcatagg actttcaact tacatttaag tgacatttaa atgagagatt
     8161 cgtcactttg gaaaacgaat aacaaatatt gcaccacctt gtgggtgatt ttgtgcagta
     8221 attgttcctc cttgtctcat aataatcgtc ttacaaagtg ccaatcctat tccataaccg
     8281 gctgtgcttg aatttttccc acgataaaat ctgttaaata gacatggtaa atcttctttt
     8341 ttaaagcctg ctccgttgtc atgaatagta agttgagtaa acaaaaagtt gtcctcacaa
     8401 atgatatcaa tttttccatt atcacccaca ctctccatgc agtttttaaa tatattttga
     8461 attgcttctg aaagccaatt taaatcaccc aaaatcctta ctccttttgg tatatcaata
     8521 tgtaaagtga tattgtgcag ttccatggga atcaaaagtt gatgaagtgc agaactaatc
     8581 aaattattca catcaatttg ttctttttga aagactacaa tacctgcatc taaacgtgat
     8641 aattttaaaa gggaagtaat cagccagtcc attcgtataa gtaattcctc tgtttctcgt
     8701 atcaactctt ttctctcatc ttcatcagaa gtattctcta acagtgacaa aataagagtt
     8761 actgatgtaa gaggagtgcg aagctggtgg gctatgtcag ctagtgagtc agcaaggtgt
     8821 tctttttctt ttttcaatgc gtaattttgc tctctaatac gtaacgtcat tttagttatt
     8881 tcactttgca gaatagaaag ttcaccctca tctgattcag caatatacag atggttagca
     8941 ttatgaagca caagattaat ttgttctgaa atctgtgcaa tacttttgta tcgattttta
     9001 gtaaacacaa aaaatgctat tccaaaggta gtggcagaaa caatagaaag tattccagtc
     9061 ataatactga ttgcaaatcc cagggctaca gtgagaatag taattaataa gaataaaata
     9121 gcaaattttc gaaactctct atttcgaaac ataacttccc cccaatctat accctgtccc
     9181 acgaacagtc aaaattattt gtggacttga ggggtcatct tctatcttct ctcgcaagcg
     9241 tttgatgtac acagtcaatg tgttgtcatt aacaaactca cctgccgcat cccacaattc
     9301 atcaagtaat cttaccctcg taataatact tttaggattg ctaataaaca ccaataacaa
     9361 acggtattct aaagctgaaa gaaaaacctc attgccattc tttttcacaa caccggttgc
     9421 tgtatctaca taaagcccac aaatttcaaa agttgaccca aaacgtccac tttttcgtag
     9481 tgctgttcta attcgcgcaa tcagttcacg tggacgaaaa ggtttagtaa tataatcatc
     9541 tgcacccata ttcagtccag taacaacact tgattcatca ccagaagctg tcaaaaagat
     9601 aacgggaatg tcttgctttt ctttgatttc tgtgcaaatc gtaaacccat ttccatcagg
     9661 taaagaaata tcaataagtg ccaaatcaaa tttattctta gcaatctcta caagtgcttc
     9721 acttcttgtg gatacatggg ttactataaa tccttctgaa ttaagcaaaa gaataagatt
     9781 tttggcaatt gctttatcat cctcaactaa aaatatccgt ttcatttact ttcatcctcc
     9841 tttattttat tagttttata tattccagca gagtaatagt acactactat tttacttatc
     9901 attacacaat tttcagtagt ttcttttgtt cttatataat ccatgcataa tacctccatt
     9961 gatttattat atttcttata acataaatac acaagataag acaaaaaaca taatgtaagt
    10021 gcaagttttt taactcacta acttataaac atacactcct actaacacta ctttcttgat
    10081 gacacatctt acaagcttat attcatacat caatgaaaaa ttaaatttat ccatttatta
    10141 aaataaaagg caatagcttc tatagctaat gccctttatc ttaaaatgat ttaaatacta
    10201 tacaattttt ataaatggct ataaataaac tcgtatagaa tataaaattt atctacagtc
    10261 ttttgttata caaaatttat aacctcttat agaacaaatt taccactttg caaacttatc
    10321 acttttactc agctatatta taaactttta atttatcttt gtttaaatgt ttcttcttaa
    10381 cttctactaa agcttttagc gtatccaaag atgtcattat ttcagtagaa aattcaatgg
    10441 ctgttcttct catcttaaat ccatctcttg tagagtcatt tcctttagtt ggtgtattta
    10501 ttactatatc aacttgttta tttcttatag catctaatat gtttggtcta ggctcttcaa
    10561 ttctatttac tatatcagcc tctattccat tttctcttaa actcttcgct gttccttctg
    10621 tagcaacaaa agtatatcct aattctttca tatcttttgc tatctctata aactcatctt
    10681 tatcatgatt atttacagta gcaagtacta ctcctctttc atcagacata tgtctacctg
    10741 ctgccaagaa ccctttatat aaggcttctt ctaaattttc tcctacacct agaacttctc
    10801 ctgtagactt catttcaggt cctagactta cttcaacttt agataattta gacattgaga
    10861 atactggtac ttttactgat actaattttg gctctttgta aactcctgta ccatatccta
    10921 aatcctttaa tttagctcct aacatacact tagtagccaa gtcaactatt ggtactccac
    10981 ttactttact tatatatgga actgttctac tagctctagg gttaacctca attatatata
    11041 attcattttg aaattctata aattgtatat taaccatacc aagcacatta aggtctaaag
    11101 ctattttttt agtgtattct actatttttt cttttatttc atcagatata ttttgacttg
    11161 gatacattgt tgtactatct ccagagtgaa ctccagctct ttctaaatgc tccattatac
    11221 caggtatcaa tatatcttct ttatcacata tagcatctac ttctatttct ctaccagtta
    11281 gatatttatc tataagtact ggatttttat ggtctctatc aaatgcatca tccaaatact
    11341 gaattagttt ttcttcgtta taagttattt ccataccttg accaccaagt acataagatg
    11401 gtctaactaa tactggataa cctaactcct tagcaatttc aacaccttca ttagttgtcc
    11461 atacaccttt tccttttggt ctatttatat ctagtctctc tagtaaatca tcaaattttt
    11521 ctctatcttc tgctgcatct atatctctaa agtctgttcc cagtataggt atattttttt
    11581 catgtaaaaa cttagccaat tttatagctg tttgtccacc aaactgtagt attacacctt
    11641 ctggtttttc tttttctatt atatttaaaa cttcttcttc tgttaatggt tcaaaataca
    11701 acttatcaga tgtatcaaaa tccgtactta cagtttcagg gttattgttt acaattatag
    11761 tttctattcc catttttctt aaagatttta cacagtgaac tgaacaatag tcaaattcta
    11821 ttccttgacc tattcttatt ggaccagaac ccaatactac aacttttctc ttatcactaa
    11881 ctactacctc atcatattgt tcataagttg aatagtaata aggtgataga gcttcaaatt
    11941 ctcctccaca tgtatcaacc attttataaa ctggttgtat attatataaa cttctcaatt
    12001 catataattt ttctgggctt atcttcatta agtcagatat acctttatca gaaaatccct
    12061 ttttctttaa ttcatgtaaa tattctttat ctaagtcttc tatttttaga acttttaatt
    12121 tttcttcttg ttctactatc catttaaatt tatttataaa ccacttatca acaccagtta
    12181 tttctgatat catttctact ttatagcctc ttcttatcat ttcagctaag tcaaatagtc
    12241 tctcatcatc aggtactact actctagcct ttaattcttc taatgttcta ccttctgatg
    12301 gagcatgaac caatgaatat tttcctgttt caagtgatct tataccttta agaatagcag
    12361 cctcaaagtt acttcctata ctcatgattt caccagttgc catcatctta gttcctaatt
    12421 ttctattggc atgtctaaat ttatcaaatg gccactttgg tatttttact accacataat
    12481 ctaatgttgg ctcaaaacaa gcataagttt ttttagttac tgcattttct atctcatcca
    12541 aagtataacc taaagctatc ttagctgcta cttttgctat tgggtatcct gtagcttttg
    12601 atgctagggc tgatgaccta ctaactcttg ggtttatttc tattatcgca tattctaaac
    12661 tatgtgggtt taaagctatt tgaacgttac atccaccttg aacctctatt gcatttatta
    12721 tgtctattga tgcctttcta agtagttgat actcttcatc acttagagtt tgacttggag
    12781 caacaactat actgtctccc gtatgaactc caactgggtc tacattttcc atattacata
    12841 cagttataca gtttccattt ccatctctca ttacttcata ttctatttct ttccaacctt
    12901 ttatactctt ttcaagaaga acttgtccaa caggacttag ctgtagtcca tgtgaaagta
    12961 tttctcttaa ttcttcctca gtatcagcta tacctccacc agttccacct agcgtatatg
    13021 ctggtcttac aactactgga tatcctatct tattggcaaa ctcaagacct gcttctaaat
    13081 ttgtaactat atcactaact attactggtt gatttatttc tttcattact tctctaaata
    13141 aatctctatc ttcgcccttt tttatagatt ctatagatgt tcctataact tttacattat
    13201 atttatctaa tataccagca tcatgtaatt ctacagctaa gtttaatcct gtctgaccac
    13261 ccatacctgc aagtaaactg tctggtcttt ctttttctat tattttttct ataaattcta
    13321 ttgttaatgg ttctatatat attttatctg caatttcttt atcagtcatt atagtagctg
    13381 ggttactatt tactaataca acttcaattc cctcttcttt taatgcttgg caggcctgtg
    13441 ttcctgaata gtcaaactct gcagcttgac ctattattat tggccctgac cctaatacta
    13501 aagttttctt tatactatct aatttaggca taactctttc tccttatcta aacaattttc
    13561 acagttctta tcttcatcat ctatacaatc aactttaatt actttatttt atcttaagtt
    13621 caaatttact catcaataca tctatttaat acatctatgt taattaaacc aaactttttg
    13681 atttaagtta ttcttgtttt ttagttagct attctaatgt tgtttatttt actaattcta
    13741 aaaatttatc aaaaatatag tcattatctt ttggtcctgg gcaagcttca ggatggtatt
    13801 gaacactgta tacatctagc ttctcatgtc gcattccttc aacagtatta tcatttaaat
    13861 ttatatgtgt cactttcatt tgttcaggaa cttctgaaac ataataacca tgattttgag
    13921 aagttataaa tacttttcct tcttctaaat ctttaactgg atgatttcca cctctatgcc
    13981 caaatttaag tttagcagtt tttcctccaa gagctaaagc taaaagttga tgtcctaagc
    14041 atattccaac tataggtttt ttaccaataa gagcttttat attttctata acatcttcta
    14101 agtcttctgg gtctccaggt ccatttgaca agaatattaa gtcagggttt atactcaata
    14161 catcttctgg agatgttgta gctggaaata ttgttatatc acatccacga gctataaatg
    14221 atcttaatat atttcttttt actccaaaat ccataacagc cacttttgga ccatttcctt
    14281 ttatatgctc tacttctttt cttgtaacag ttctaactgc ttctgtattt gaaaacttat
    14341 ccaatttatg tttaacatct tctaatttac tgtcttctaa tgtaattata cctttcattg
    14401 ttccattatt tctaagtatc ttagtcaaag ctcttgtatc tattccttca agtccgataa
    14461 ctttattttg ctttaaatat tggtctatat caatttcaca tctaaaatta cttggagaat
    14521 cacttttctc ccttactatg aatcccttta cttgaacttt ttcagactct gctgatgata
    14581 aatttatacc ataatttcct acaagaggat aagtcatagt aactatttga ccatagtaag
    14641 aagggtctgt taaaacttca ccatatccta tcatcgaagt attaaatact acttctccta
    14701 cactttcttc taaatatcca aatgcctttc ctataaaaac tgttccatct tctaatatta
    14761 accttgcttt catactacag tacctcctat aattctcttt agacaaacta aagaacatta
    14821 actaaatata agcttttaaa tatctatatc tatttttcac ttttacattc tagttttata
    14881 cttatttaca tttatttttt atctttttct attatactac aaatttctta aaaaaaagaa
    14941 gttatctcaa aagtaaaaac tcctagaaaa aataacctct ttttttttat ttaataatta
    15001 aattcttaaa ctatacaatc aacttaattt ctattcagct atattgtaaa cttttaactc
    15061 atctttattt aaatgtttct tcttaacttc tactaaagct tttagtgtat ccaaagatgt
    15121 cattatttca gtagaaaatt caatagctgt tcttcttatc ttaaatccat ctcttgtaga
    15181 gtcatttcct ttagttggtg tatttattac tatatcaact tgtttatttc ttatagcatc
    15241 taatatgttt ggtctagatt cttctactct atttactata tcagcctcta ttccattttc
    15301 tcttaaacta ttagctgttc cttctgtagc aacaaaagta tatcctaatt ctttcatatc
    15361 ttttgctatc tctataaact catctttatc atgattattt acagtagcaa gtactactcc
    15421 tctttcatca gacatatgtc tacctgctgc caagaaccct ttatataagg cttcttctaa
    15481 attttctcct acacctagga cttctcctgt agacttcatt tcaggtccta gacttacttc
    15541 aactttagat aatttagaca ttgagaatac tggtactttt actgatacta attttggctc
    15601 tttgtaaact cctgtaccat atcctaaatc ctttaattta gctcctaaca tacacttagt
    15661 agccaagtca actattggta ctccacttac tttacttata tatggaactg ttctactagc
    15721 tctagggtta acctcaatta tatataattc attttgaaat tctataaact gtatattaac
    15781 cataccaagc acattaaggt ctaaagctat ttttttagtg tattctacta tcttttcttt
    15841 tatttcatca gatatatttt gacttggata cattgttgta ctatctccag agtgaactcc
    15901 agctctttct aaatgttcca ttataccagg tatcaatata tcttccttat cacatatagc
    15961 atctacttct atttctctac cagttagata tttatctata agtactggat ttttatggtc
    16021 tctatcaaat gcatcttgta ggtattgaga taatttttct tcgttataag ttatttccat
    16081 accttgacca ccaagtacat aagatggtct aactaatact ggataaccta actcattagc
    16141 aacttcaata ccttcgttaa gtgaccatac accctttcct tttggtctat ttatatctag
    16201 tctctctagt aaatcatcaa atttttctct atcttctgct gcatctatat catcaaaatc
    16261 agttcccaat ataggtatat ttttttcatg taaaaactta gccaatttta tagctgtttg
    16321 tccaccaaac tgtagtatta caccttctgg cttttctttt tctattatac ttaaaacttc
    16381 ttcttctgtt aatggttcaa aatacagctt atctgatgta tcaaagtctg tacttacagt
    16441 ttcagggtta ttgtttatga ttatagtttc tatgtccatt tttcttaaag attttacaca
    16501 gtgaactgaa caatagtcaa attctatacc ttgacctatt cttattggac cagaacctaa
    16561 tactatcacc tttttcttat cactaacaac tacctcatca tattgctcat aagttgaata
    16621 atagtaagga gatatagcat ctatctcacc tgcacaagta tcaaccattt tatatgctgg
    16681 tttgatattg tatagacttc tcaattcata taatttttct ggacttatct tcattaggtc
    16741 agatatacct ttatcagaga atcccttttt ctttaattca agaagatagt ctttagttaa
    16801 atcttcaatt ttcataactt ttaatttttc ttcttgctct actatccatt taaatttatt
    16861 tataaaccat ttatctatac ctgtaatttg ttctatcatt tctactttat agcctcttct
    16921 tatcatttca gctaagtcaa atagtctctc atcatcaggt actacaactc ttttctttaa
    16981 ttcctcaatg cttctctctt cagatggtgt gtgaactaat gaatattttc ctgtttcaag
    17041 tgatcttatc cctttaagaa tagcagcctc aaaattactt cctatactca taatttcacc
    17101 agttgccatc atcttagttc ctaattttct atttgctttt ttaaatttat caaaaggcca
    17161 ttttggtatt tttgccacca cataatctat agttggttca aaacaagcat aagttttttt
    17221 agttactgca ttttctatct catctaaagt ataacctaaa gctatttttg acgaaacttt
    17281 agctattgga tatcctgtag cttttgatgc taaagctgat gatctactaa ctcttggatt
    17341 tatctctata actgcatatt caaaactatg tggattaagt gcaaattgaa cgttacaacc
    17401 accttgaact tctactgcat ttaatatatc taaagatgct tttttaagca ttgcacattc
    17461 tttgttactt aaagtttgag ttggagcaac aactatactg tctcctgtat gaactccgac
    17521 tgggtctata ttttccatat tacatacaac tatacaattt tcctttgaat ctcttattac
    17581 ctcatattct atttctttcc aaccttttat actcttttca attaatactt gtccaacagg
    17641 acttaattgt agaccatgtg aaagtatttc tcttaattct tcctcattat cagctatacc
    17701 cccaccagtt ccacctagtg tgtatgctgg tcttacaact actggataac caattgtaag
    17761 tgcataatca agacctgctt gtaaatctgt aactatatca ctaactatta caggctgatt
    17821 tatttctttc attacttctc taaatatatc tctatcttca ccttttttga tagattctac
    17881 tgaagtacct attattttta ctccatattt atctagtatg cctttttcat aaagttcaac
    17941 tgctaggttt agccctgttt gtccacccat acctgcaagt aaactgtctg gtctttcttt
    18001 ttctattatt ttttctataa attctattgt taatggttct atatatattt tatctgccac
    18061 ttctttatca gtcattatag tggctggatt actatttatt aatacaactt caatcccttc
    18121 ctctttcaaa gactggcaag cttgtgttcc tgaatagtca aactctgcag cttgacctat
    18181 tattattggt cctgacccta atactaaagt tttctttata ctatctaatt taggcataaa
    18241 tttttctcct tatctaaatg gtttttacta tctgtaaata atactaaatc tatattaatg
    18301 ctaagaattt attaaatata caatctaaat cttcttttgt tgtgtattct ggaatgtact
    18361 gaacactata tattggtaat tccttatgtc tcattccttc tatagtattg tcatttaaat
    18421 ttatgtgagt tacttctgta ttttctggca tttctgaaac attatatcca tgattttgag
    18481 aagttataaa tacctttcca gtttctaaac atttaactgg gtgattacct cctctatgtc
    18541 caaatacaag ctttgaagtc tttcctccta atgccaatgc taaaatttga tgtcctaaac
    18601 ctattcctgt caatggcttt ttgcctatta atttttttat attttcaact atatcattta
    18661 tatcctctgg atttcctggg ccattagata ataagattaa gtcaggattt atatttaaaa
    18721 tttcttctac tgtagtcatt gctggtacta tagttatatc acagttacaa gccttaagag
    18781 actctagtac actattttta acaccaaagt ctataactac aactttagct ccaggacctt
    18841 ttatattttc aatttctttt cttgtaacat tttttactga atctttgtta caatgctctt
    18901 ctaatttaga ctgaacatct tgtaatgata cattttctaa agttataatt cctctcttag
    18961 ttccattgtt tctaataatt ttagttaatg ctcttgtatc tattccttca agtcctatta
    19021 ccttattttg ctttagatat gtgtctatat ccatttcaca tctaaaatta tttgggttat
    19081 cacttttttc tcttacaata agtcctttta cttgcacctt atttgattca acatcttcta
    19141 aatttattcc atagtttcct ataagtggat aagtcatagt aactatttgt ccataataag
    19201 ttgcatctgt caatagttct ccatacccag ccattgaagt attaaataca acttctccaa
    19261 tagcttcctt tagatatcca aatgcttttc cttcaaatac tgttccatct tctaaaatta
    19321 atttcccctt catgtaagct acctcccaaa tattttatct aagcattttc tatttctttt
    19381 acaatattaa tagctgattc tcttggattt tctgcttttg ttataggtct tccaacaact
    19441 aaataatgag cacctttttt tattgcatct gatggagtta caactctttt ttggtctcca
    19501 acctctgctg atttaggtct tattcctggg caaactgtta taaaatcagt tccacatgct
    19561 tctactattt tatctacttc ttgcgctgaa caaacaaccc catctattcc tgattctttt
    19621 gccagtttag ctctctttat agctaactct tctgttgtca tattacatcc tatgtcctgt
    19681 aaatcttggt tgcttaatga agttaaaact gttactccaa ctactaatgg cttttctata
    19741 tttaatcttt ctgcttcttc cctagcaatt agtgcacatt gtctcattcc ttccatatct
    19801 gatacatgta ttgtcattaa ccaaacatta tctctcactg cagctttcac tgcacttttc
    19861 atagtatttg gtatatcatg gaatttaagg tctaaaaata tttttttccc tttttcttta
    19921 agataatcta ttgttttacc ttttgtggca acgtattgct ctagccctac cttaaatatg
    19981 tctacactat cttctaatct gtctattagt tctttagctt tatcaaattc gtcagtatca
    20041 attgcaacta tcaatttttc tttaccattt atcattttta catctccttt ttaataaagc
    20101 ctaaataatc ataaaaaaat cctcacacca aaagaggcat aaggatttta tctatacata
    20161 actctattca ttagctatga gatatctttc ccagtctctc tggactagtt taaaagactt
    20221 tattatattt aaatttttat tttatactca tcaaaaacct ctagaagatt tactagaggt
    20281 tatatactaa cattatctat aaccctttag tctctctgga ctactttaag gaatttagct
    20341 gtaatatttt tctttattta tataacttta tgtatctata ggataattta aagttttatc
    20401 ttttttataa ttaaaccact aattgctttt tatgtcaata agtctttgaa ttattcttca
    20461 tctttatcaa acaatttttt ctcaaaatat gattctgcat tatatattgc agcaactgga
    20521 ttatgcccag ttactctatc tttgacaact aaagttgtta taggagcttc catatatttc
    20581 atggctaaag tatcgtgacc aacacataat ccaagaatta cattaaggtc aaccttagct
    20641 tcatttaaaa ataaagcttg tcctattgga ttgcacatta cctcatctga acactttgat
    20701 attgtttgag atgcttctag tccaattgta ctcttaggca ttgccccatt tttacatata
    20761 acagaaaata cttcaaaccc atgatgttca aatatttttt gcactgtttg catttctctt
    20821 tttagtccaa tacaaaatgc tatgccaatc tttttataac cacacttttt agcaaactct
    20881 ataatctctt ttagtctagt atattgacaa tacccccctg cttcaactaa tccagcatta
    20941 taagctattt ttctattctc ttcttcttca taaagttgct ttgctttttg ttgtagttca
    21001 atttctctag ttggacatat cttcattaat ttatccatat ttccattaga acagcctcta
    21061 agattacatt ttccacactt atacatatcc aatatcccct tccaaaattt tattcatctt
    21121 gcgattcttc tttttctaga gttacatttt cttcttgggt ttcttcttct ggtttcacat
    21181 gctcgactac agttataaaa tatgattttc ctattttatt ccttatagga agtttttcat
    21241 atgaaacatc tattttattt tttatacaag ctatatcaaa atgtcttaag gctacaccta
    21301 agctaacctt attcatatct tcacagtgtt tcttaggtct cttttcaaat aaatgaagac
    21361 ctcgttcatc cttatggaaa taccacggtt gagaattttt tacagatgga gctcttcttg
    21421 tcaattctaa gatatctttc cactttctat tcctatttat cttatttatc atatctttta
    21481 ctggctttct atcaggtcta gcatatctcg tcctaaacaa ctcttcattt tttgctggat
    21541 atccaaatgc tattattata taaggatttt ctattttgtt ttcatcatct tcttctgttt
    21601 ttattccagc tagataatct aaatcatctt cctcatcttc ttcaaaattc ttattcccaa
    21661 tatctacaaa ttccaagata tcttctctct ttaagtttcc ttccaaccag caagtagcta
    21721 ttcccaatgt tgtaaggcgc aaaactacac cttctgtagc aaatcctata ttctgtaaat
    21781 agtcctcacc tttgtctgat gtaactacta tataatgagg tgcctttact ttacattcct
    21841 tacccatcaa aaaatgtatt atatgacctc tatcaacaac atgtgcttta atatttaaat
    21901 cttcatttaa gtattctaaa tttttacaac ttctttttat ttcttccatc aatggctttt
    21961 ttatcttttt actggaaaaa tttcttacag attttctata aaaaatggct tcataaagct
    22021 ccatttatgc cctcctaact gaaatcttct gacgtataaa ctctataaat ttatataaat
    22081 actttatatt ttttatagtt ttatttcctt tttcctcctg ccctattttg aaattcataa
    22141 gaatatctac tctagtttaa tatagcattc aaaaggctta aattctacct tatcaatgtc
    22201 tatacattag cataattttt ttatttgatt ttctatgcta atttaaataa caacactagc
    22261 tattaccttt ttaattaagc tttgccagaa aaattttttt tcatttataa atatctatct
    22321 cattattata ttataagttt ttttcggtat tcttgtatag cttttcacta aaaaagtatt
    22381 tttatttcta ctttaatatt attatcaaca aaaaacatac tgcttaaata agtttgttat
    22441 cctcataatc tgttttaatt aaaatatttt tttatttctc aatctataaa gtataaatat
    22501 tttgaatatg acccaaaatc taagtaaagt tataatattt tataagttgt tcaatattaa
    22561 aaacataagt aatgttataa tactttataa gttattcaat attaaaaata taggaggata
    22621 aatatgaatt taaatagaaa tttagaaaaa tacgctgaat tagcaataaa agttggagtt
    22681 aacatacagc caggtcaaat tctacttata aagtcaccaa tagaatgtgc tgattttgca
    22741 agaaatgcac ttaaagaagc atataaatgt ggtgctaaaa atgtttatat agagtggtct
    22801 gatgaagaaa gtactcttat taaatactta tatgctccag atgaagcatt tcatgagttc
    22861 cccaaatgga cagcagaaca atatgtagat atagcaaaag aaggtggggc atttttatca
    22921 gtctatgccc aaaatccaga tttattaaaa gatgttgacc ctgaaagagt tgcaaatttt
    22981 cagaaggcat ctggaaaagc tttaaaagaa tggcgttctt acactctaac tgataaatgt
    23041 aaatggagta tagtctctgt gccaacaaaa gattgggcaa aaaaagtgtt tccaaattta
    23101 tcagaagata aagcaataga aaaactttgg gatgctatat ttaaatgttc aagagtagat
    23161 ggtcaggacc ctataaaagc atgggaagaa cataatgaaa atcttaaatc taaaatggac
    23221 tttctaaata aaaataactt taaaacttta aaatataaat cctcaaaaac tgatttgact
    23281 ctagacttgc caaagggtca tgtttggcta agtggagcat ccaaagaccc taatggaata
    23341 agttttaatc cgaatattcc aactgaagag atttttggaa tgccacataa gtttaaagta
    23401 aatggaactg tttatagtac aaaacctctt gtttatggtg gaaacataat tgacaatttc
    23461 ttcttaacat ttaaagatgg taaaataata gatttctctg ctgaaaaggg actagataca
    23521 ctagaaaaac ttattgaaac ggatgaaggc tctcattatt taggagaagt cgctcttgtt
    23581 ccatacaact caccaatatc caatacggat ataatttttt ataatactct atatgatgaa
    23641 aatgcttctt gccactttgc aattggttct gcttataaga cttgtctgga aggtggaaat
    23701 aatttaaaag atgaagaatt ggatgaacat ggtgtaaatg acagtttaac acatgtagat
    23761 tttatgattg gttctgctga tatggatatt attggtgaga cttatgatgg aaagcaaata
    23821 cagattttta aaaatggtaa ttgggctttt taacatatga ttttaactaa aaagggctga
    23881 tggaagttat accagacttc ccagcccttt ttaatgttga tgataaatat tttttatatt
    23941 aattaatctc attattatag attaattcct attgttttaa acataagtat ctaaaactta
    24001 tatttatatt atatataaaa tatcctattt agtaaaacct ttattttaat ttatatgcta
    24061 aaaatttaac tttgctattt caacagcaga ctttgcatcc tttgaataat aatcagcacc
    24121 catttcttca gcgtattctt ctgtcaaaac tgcacctcct acaaatacct ttgcatttat
    24181 ctcattatct ctcagtgcct gaattgtatc tttcatactt tgaacagtcg tagtcataag
    24241 tgcacttaat cctactaatt ttatatttct ctttttagca acttccacta cttcttcaat
    24301 agggacatct ttacctaaat ctataacttc atatccataa ttttctagca ttatttttac
    24361 tatatttttc ccaatatcat ggatatcacc ttttactgta gcaactatta tttttccttt
    24421 ggatacatta ttgctacttt tacttaataa agtttccttt attgtattta atgaaacttt
    24481 taccgtttct gctgattgaa tcaattgtgg taaaaatata tctccactat catatctttt
    24541 tcctacttta tcaagagcag gaattaaaat ctcatctaat atataatttt catccttctc
    24601 ttttaaaaga ttcagtgtta cattttttgc ttcatctttt aatcctcttt caactaaaat
    24661 atccaagggc aaatctttat caatctttgt agatgaatcc gatttttttg aattatttat
    24721 attgctatat tgatttatat agtttataca tcctttatct gtgttattta atattttaaa
    24781 agaattgata gcttccatca tactatattc atttggattt ataattgcta aatcaagccc
    24841 tgcccctaaa gctaatgtta gaaaagaagc attaagtgct ttcctatttg gaagaccaaa
    24901 tgaaatattt gaaacaccta atatagtttt tactcctagt gtctttacca ttgttatagc
    24961 ttttatagtt tctattgctt cttcttgttg tgctgaaaca gttaatgata aacagtctat
    25021 aaatatatct tttggtttta tcccataaga aactgctcta ttaactatcc tttttgctat
    25081 ttcaaatctt tcttcagcct ttttaggtat ccccttttca tcaagtgtaa gtccaaccac
    25141 acatgaacca tactttttaa ctattggtaa tatactttct aaagactcct ctttgccatt
    25201 tacagagttt actattgttc taccattata atatctaagt ccttgctcta aggcctctac
    25261 attggaagaa tcaacttgta aaggtgtatc tactactgct tgaatctctc ttattaattt
    25321 tggcattagt tttttttcat caatctctgg aagaccaaca tttactccaa gtatttgtgc
    25381 tccagcattt acttgttcta aacctaaatt tatagcataa tcaacatttt cattttttaa
    25441 tgcttcttgt agagattttc tacctgtggg attcaatctt tctccaacaa ctataggcga
    25501 ttgtacttcc acaaattttg atggtgaaca gactacacat ttatcaattt tctcgataca
    25561 tccctttgta acagaattta tattctcaga tatttctttt ataaaacttg gattcgtacc
    25621 acaacatcca cctattatag tagcaccaac ttcaacgaac tttttaaccc cttcaaaaaa
    25681 ttcttttgca tcaacatcat atatagcctc tccatcaact atatttggaa gacctgcatt
    25741 tgcttgaacc ataacaggga ctgtagctct tgatgctatt ttttcaacta ttggtaaaag
    25801 ttgtttaggt cctaatgaac aattaactcc tattgcatct acacctagac cttctatagt
    25861 agccaccata cattctggca tacatccagt aaaacttctt ccaccttcat caaatgtcat
    25921 agtacagaaa ataggtaaat cagagttttc ttttgctgct aatacagcta ctttagcttc
    25981 atataaatcc atcatagtct ctattactat tacatcaact ccagatttaa cgccttgtag
    26041 tacttgtctt ttaaatattt catatgcttt atcaaaactt aaagtaccca taggctctag
    26101 catttctcct ataggaccaa tatctaaagc tacatatctt ggtttagtat tatctacatt
    26161 ttctatagct tttctagcca ccaaaacagc attgtcaatc acttcttcta ccgtatactt
    26221 actatctaat tttagttcat tacatccaaa agtatttgta agaattacat tcgaacctgc
    26281 ctctaagtat gctgtatgta tttctataag tttatctgga ttttgaagac caaatacttc
    26341 tggattttca cctaacttta accctttttg ttgaagcatt gttcccattg caccatcaaa
    26401 tattaatata ttatttttca gatattgtct tatttccaca agagttcgct ccttttctat
    26461 atgtacagtt tctatagttt ttacaatttt cacacgactt ttctttctta gatttattta
    26521 ttcttgtatt agaaatacct ataatagcca ctactgactt tctcggtatc ataattccat
    26581 tagaagtaat tgttagacct atttgttttt gagcattcaa aacgtttaat atatctatat
    26641 ttttttctat tggtaaatct ccatatcctg ggctatatcg catagttata aatttatctt
    26701 gctttaaaaa aaccttttct aaattatttt gaacaatgtc acacacttct tctattgctg
    26761 ttgttccaca tgaatcaatt attagtcctt ttgttaaatt tgaataagag tgtcgtctta
    26821 tttctttttc tatatctatc cctatagtag ctgccataat tacacactca ttacattctt
    26881 ttaaaagttc atatacatct ttactctcta atgttaaatt tgttccctct aattctacaa
    26941 cattatcttt atttatttta ataggataaa tcctagataa atatctagga tttattttat
    27001 ttttagttat agctacacat tcatcaatag tatatttaag gtctttatct atctcttgac
    27061 ctctgtattg taaatatctt aaaacttcac tttgatttat gcttatatct tctcttccaa
    27121 ttaaattatt ctccatatat atttaaagaa aatcctttat ctaaaacatc ttttgcatat
    27181 tcctttgccc caaataaaga taagtctctg tagtttccac attctatagc tgtagctgct
    27241 ggcattttat ctgattcaag aacttttttt aatgcttctt ctaaaccaat cttaactgtt
    27301 ttggcatcta catctcccca tagtattaaa taaaatcctg ttctacatcc cattggagat
    27361 aagtctatta caccatctaa tgtatctctt aaataagtag ctaaaagatg ctctaaaccg
    27421 tgcatagcag cagttccaaa actttctaca tttggctgta aaaatctcaa gtcaaattta
    27481 gttactttat ctccctttac tccatcaagt acactacact ttcttacaaa aggagctttt
    27541 acttttgtat ggtctagctt aaaactttct actttttcca ttatttaatc ctccattata
    27601 ctttaaaatt tgttacatta attctaaaaa aaactcttcc tatctattat tgataagaag
    27661 agtatattat ttcaagtcat ctcatcgttg ttagcaggac cacctgataa aaggttggta
    27721 taggatcact gagctaactc tctcccctaa ctcttgataa gtatcttatt aaactgactt
    27781 aaattatata ttactttttt atttttgtaa acactttatt gttataatat ttatatcaca
    27841 taatcgtact tttattttat aactaagctg attgtattat tggcagttgt acttcaaaca
    27901 tagtttgata tttatcgctt gaaacagtaa tttctccatc atgtaaattt acaatatttt
    27961 ttgtaatcgc aagacccaat ccagaacctc caacatttct atttctcgat ttttcaactc
    28021 tataaaatct atcaaatata tttggtaaat ctaacactgg aattggttcc ccataattta
    28081 tcacttttac aaccgccata tcttcctttt tctctgtgac tatatctaca taatgcccat
    28141 cttttccata tttcacagca ttagttataa gattttcaaa tgctcttacc aatttatttg
    28201 gatcagcttt tacaattaat ttttcttcat taaaattaat tctactaacc ataaattctt
    28261 gtttaaaata aatttcaaat tgagatacta cttgacttaa taactctact aaatttattt
    28321 ctattttgtt taattttatt gtattatttt gcattttagt caattcaaac aaatcattta
    28381 taagaacatt taaatttttc gatttttcat atgcaatatc aacataatac atcatctgaa
    28441 cttcatcttt atacttacct tcttctatca ctcctaaata acccattatg gatgtcaaag
    28501 gtgtccttaa gtcatgtgac acatttgtta ttaaatctgt ttttgtctgc tgagcttgtc
    28561 tctcttcaat agttatattt ctaagttgat ggactatatt attgatttta tgtgctagtt
    28621 catcaatatc atccttttct ttatccttta atatatctaa gtcatactca atatctatac
    28681 ttttttctaa gttaccttca tccattaaat ttacagcact tttaatgatt tctaattttt
    28741 gattttttct attagtcttt cttataaaat ctacaatttg cttatttctc ttgtacgata
    28801 tcatggaata aattgctaat gatgtgattg taaataaaaa tggataaaat aaactctctc
    28861 ctataagact tctgagatct cttaactgat atacaagttg attaattaca gatatcccac
    28921 tattgaaata taatgatttt attatataca tacttgttaa aataagcatt gaagttaaag
    28981 cacagcttat tataagatct aatatgggtc gaaacatatg atttaataaa cttttatttt
    29041 tcaattttat atcctactcc ccatacagta tgaattattt tttctccatc tgtatatttt
    29101 tcaattttat cccttattct gctcatatga accattacag tattattaga ttggtaatat
    29161 ttctctttcc ataccttttc aaatatttct tctgtactat atactctgcc tttattattt
    29221 gctagtaaat ataatatatc aaattctctt gatgtcaaaa ttatttcatt tccagccact
    29281 gttacactat gtttttcctt atctataatt actactccaa cctttatgac atctttatct
    29341 tcattattag caccactaaa ataatatgct cttctaatca gcgacttcac tctcacagta
    29401 agttcaagtg ggttaaatgg ttttgtcaaa taatcatctg caccagtcat tatcccttgt
    29461 attttatcca tgtcttctga ttttgcactt aacataagta ttggtatatt caaactttct
    29521 ctaacttttc tacaaacttc tatcccatcc attttaggca tcattatatc caatatcatt
    29581 aaatgaatat tttccttttt taaaatatct agagcctctt ttccatcttc agctttaatt
    29641 acattatatc cactatttaa aagatatatc tctataaggt ctcttatttc cttttcatca
    29701 tccacaacaa gaactgtatt attcattttt acacatccta acttaatctt tgtatatagc
    29761 tttattcata taaaattata ctatatttta gttagtgtaa tctataaatt tattaatttc
    29821 taaatttcca atataataca aattatttac acatttatat tatttatttt gtaaatattc
    29881 ttctaaagtt aatccttttg aataaatttc ctcggcagca tccttaccaa catatctaat
    29941 atgccatggt tcatatgctg tacctgttat atcttcttta ccttcaggat atcttattat
    30001 aaatccaaac ttgtgagcat tttctgccaa ccatttagct tcttttgtac ttccaacaaa
    30061 ccatctttct ggatttgtta aatcaataca aagtccagtt tggtgctcac tgtaaccagg
    30121 ctttgctaca tatgcatctg ccttttctcg tccctgagat tttacccttc ttgtataagt
    30181 atccagttga gtatcataag atctgtatgc tgaagaccct aaaaactgta ttccttctga
    30241 attagcttgc ttaactaaat cttcaactgc ctttgcaggt tctcctgcca tttgtttttc
    30301 ttcctctgtt gcttcttcaa caaaaggtat gtttacctta gtaatatttt caggagtata
    30361 gtttttgcta attccatttg tcttgtttac caataatata tttgatatac tatttgagtg
    30421 atttttattt tgagaatttg cctcaacatc ttgttctgaa tcatgttgag cagctactat
    30481 tggatcgtta tctttcttaa gtaatctatc tttagatata aatacactta taaatactac
    30541 taaaataatg gctcctatta atttaaattt tttcataatt aaatcttctc ctttttgtta
    30601 tgtttgctat aatgttaatt ttagagtata agacttaagt attttataag taaatcttaa
    30661 ataaatctta aatttaatat ttttaaagga tggtgataaa atgtctatac aaaaacttct
    30721 aagtaaagct cgtaaggcta tacaagattt tgatatgata caagaaaatg ataaaattgc
    30781 ggttggactt tctggtggaa aagatagttt aactttactt catatactta aaagttatca
    30841 aagattttct ccacaaaact ttgaattgat agccataaca ttaaatactg gaggtgttga
    30901 taattctcca ctagataaat tgtgtaaaga aataaatgtt cctttttatg aatttcaaac
    30961 tgacataaaa gaaattgtat ttgatataag acaagaaaag aatccttgtg cattatgtgc
    31021 taatttaaga agaggtgctt tgaacgataa tgctaaaaaa cttggatgta ataaagtagc
    31081 tcttggtcat cataaagatg atgcaattga gacattttta atgtctatgt tttatgaggg
    31141 tagagtaaat tgtttttccc caaagacata cctagacaga caggatttaa cagttataag
    31201 acctatgatt tacatagaag agtatatgac taagaaaatt tcaaaagatt ctaactatcc
    31261 tattatcaca aatccctgcc ctgcaaatgg tcatactagg agagagtaca taaaaaatct
    31321 tattgctaat ttaaataaag agatgcctga ttttaaaaga aatgtatttg gtgctttaaa
    31381 taattctgag aaattgttta tatgggataa agagaagata aaaaatttta aataataatt
    31441 aaaattttta aataaaaaag caagattgta ttaattgtaa ataatcttta tataatctac
    31501 acaatcttac ttttttattt attatatgtt attatcttta atctatattt taatagttct
    31561 taatagtatt tattttgtct aatacattaa ttataactta aatattttat atattaattt
    31621 aatctattaa ttcattcaat ctactggttt aatccatttt tacagtatat acatctacat
    31681 attataaaaa gcaaaattat attttctaaa tattttatgt tagattataa tattaaattc
    31741 tattatctct ggtatattaa aaaatctaaa tggtaacttt gtacttccaa gacccgaact
    31801 cacatataaa tgatttccat ttatatcata aaacccttta gtatatttcc ttccatatgg
    31861 aggagtaact aatgctccct taataggtaa tcttatttga ccaccatgac tatgcccaga
    31921 tagaactaaa ttcattgtat ctttactaag cttatctact aaatctggtt catgtgctaa
    31981 caataaatta aaacttttat tatctatttg actctccaga tattttatat taggatttcc
    32041 atttaatatt tcatcaacac ctaatatatt aatatattta tcatctttta attttatttt
    32101 tttattttca tttactaaaa gattgaagtt ggaatttttc ataatctgcc tataatacct
    32161 aggaagttta tacatataat catgattgcc aaatactgaa aattttccca acctagcatt
    32221 catacttgat aaaatagttg taatttcatc tacacttgga tttttattgg agtaatcaat
    32281 taaatcacca gtaaatacta ttatatctgg attcaaagtg ttaatcttat tagctacttt
    32341 tttgagattc ttagttgaat aaaaactacc tatttgagta tctgaaattt gaactacttt
    32401 tacactttca gatttactct caattgtatc attttttatc aatgctccat tttcacttat
    32461 attatatttt ttcacaatta atagactcgg ctctatcgca actgagtata taaaaatcaa
    32521 aataaatatt aagataaaaa attttaaaaa atacttaatt tttgagttca aaatatctac
    32581 ctacttattt atttttttaa actatttgca ttacagactc aactttgttc atttttctgt
    32641 catgcatttt tggcttattt gctgaaaacc atttatatgt tgctgtaaga ccttctttta
    32701 gtaacacgtt tggtatataa agcccatgtt caataagctt atttatatca agattaaagt
    32761 ctatatttct aaatgggaaa tacgttcttt ctctaaactc tactttttcc atatctacat
    32821 attttattat aggttctttg ccaataattt ctccacatgt atatataagg tcatcccaag
    32881 aaattaactg tggatttgtc acattatagg cctctcttac atgaggattt ttcattatgc
    32941 tttccaatac ctttaccaaa tccccaatat atataaattg attactaact tgttttcctt
    33001 ttggtactgg tatcttttca tttttttcta ttttttcaaa gaaataatac tctctatata
    33061 aattattatt ttcaccatat atgtaagttg gtctaataat tatatatggt atagggctat
    33121 ttataataaa atcttcagcc tcttttttat ttaacccata ttttccccag ttttcatttt
    33181 cacctttctc attttcttct tttatatttc ttccactatc tttatatact gctcctgctg
    33241 acaatactat atactttttt aagttatcca tgcttataaa atcaatcaga ttacttacat
    33301 cttcttttgt atatgctgtc atatcatata tgtaatcata ttttcttcct gtgataatgt
    33361 tttccatatc ttttcgaact tttctatcac aaattagatg ttctttaaaa ccattataat
    33421 ctatttcctt tttaccattt gtaagtatat caatttgata cccacattta atcaagcgct
    33481 tagcaagtgc agaacctatg aagtcgcttc cacccataat taaaatagat ttcattttaa
    33541 gtgcatcctc ctctttttta aatgacttcc ttaactataa tatcatattt ttaaatatgc
    33601 gacaccattt tgtaatattt ttgtctataa aagatattta taacaaaata tcttttatag
    33661 actctacatt ttcgacaata taagtaggtt cactttcact aatctcttca aaagaaccat
    33721 acccatacaa tactccaata gaatctatac ctattttttt agctccaatt atgtcatact
    33781 ttctatctcc aaccataata actttatctt tatcttttac attacatagg tctagtacat
    33841 attgtataac ttcattttta ttcactcttg taccatcaag attgctacct gctatatatt
    33901 taaaatatct atctatatca aaatatctaa gtatagtttc tgcaaaaact gttggcttag
    33961 aagttgctac taataatatt ttaccatttt tatagagcat ttctaatatc tctttcatat
    34021 tctcataaat tttattttca aatatccctt tatcagcaaa atattctcta tacttttcaa
    34081 cagcttcttt agctttttta tcttcaaatt tataatactc cttgaaagta tcatgtaatg
    34141 gtggtcctat aaattggtct aagttttcca aatcttcttt tatgccaaaa ctatttaaag
    34201 aatactgaat agactttgtt attccttctt tagggtctgt aagtgttcca tctaaatcga
    34261 ataatactat ttcataattt tttttcatat ttcagtcctc catatttgta aaaagtaata
    34321 tcttatatat taagtttatc tattttaaaa agctatagta atagaaattt ctaatactat
    34381 agcttaagta ccaattaaat cttatatatt tattttaaaa ataaatttaa acagctctat
    34441 ttaactgtta tagctgaaac tggacatcct tcttcggctt ctttacataa atcttgtaaa
    34501 tctgctggta tttctccttc aattgctact gaatgccctt catcgctcat actaaaaacg
    34561 tctggacatg ttcctataca tgctccacaa gctacacata catccttatc aacaaatgct
    34621 ttcatactaa aatacctccc ctaaaattat tattttttaa ttgttgtttc cttagatatt
    34681 tatccaatat ataccaattt aaacatatat ttattatttt atcactattg tttagtttat
    34741 tatagtattt tcgtatccat gtctataaac ttcactgctt ttcatccatg attttacagt
    34801 atattgcaat cttaattttt tatttaaaac aagttcatta ttattgtagt cttttataat
    34861 atcattacac tcctccattg tgaatattgt aaaatcacct tctccaccaa tctttattct
    34921 gcctttattt ccatgtaaat cgaaaatctt tgttgggtat tcagttactt tttctataca
    34981 cttttctagg gatatcccaa gttccataat tttatttata acatttaaaa gagaatagtt
    35041 tacgtctttc atgtttttta tatgcatatc agtacttatt aggtcaggct ctaaaccttg
    35101 ctttattgct tttttaaaaa ctttaaaatc aaattggtcc actccataac atacatcgaa
    35161 caatactcct ctattctttg catttattac tgattttctt aatgtgccag attctttaag
    35221 gattccattt gtactatttc catatactgg tgtaaccaca tctccttttc ccaaaatatt
    35281 cattacttca tctatatatg atggatactc tcctatatat accactaagg gtaaatttaa
    35341 ttttttagca acttgctttg atttcttaat tatatctata ccactttcat tagattgaaa
    35401 tttactcgct tttactttta taccctttat cttttctata tttttttcta caactgactc
    35461 aaccttgtca aaatttataa catctaaaga agttgattca ttcaatatat ttagtccctc
    35521 atttgtaaca tttaaaaaag aatatacttc tgttttacac tcatccatat actttttttt
    35581 aaaatcatag tagtttgaag gaccagctgt acctgcatca aatataactg tagaaccttt
    35641 ttcaattcca attgaatcag aatccatacc tgtaggtaat tttctcttat aacaatgggt
    35701 gtgaacatct ataaatcctg gggaaatata catattatcg gcatttatta tctcgaactc
    35761 tttatttgta agtaattttt cttttcttat tttctcttta aggttcaatc caatagcata
    35821 tattttccca tgtaaaacca agatatctct tttttcaaat ttgataccat ctgttggaga
    35881 tattattgtc ccatttctta taagtaaatt tttcatttat tccacatcct aattacaata
    35941 taatttctct aatagctttt cttacataaa gaaaataagc ctaaaaataa aaatatttta
    36001 gacttattca ctatattata ctatattaat tatattaaat taaataaaat ctttaattta
    36061 ctttaagaag caattaagta tttgttgctc ggcttcttct tcagtaagac ctaatgtcat
    36121 catctttagt atttggtctc ctgcaatctt tccaatagct gcttcatgta ctaaaagagc
    36181 atctggatga tttgcagcaa tttcaggtat agcactaatt tgagaatttc ccataattat
    36241 tgaatcacat tgaacatgtg cagaacaaag ggaatcccca ataacacaag gattaaactt
    36301 ttgcttagaa ttatcttgcc caactgtacg agaaactact tgagcagaag agttttcacc
    36361 ctctaagata accttcatat tagattctgc aacttgatta ccatgagtta ataatttctc
    36421 aaatacaact attttagctc ctttacctag gtttgcatcc atttctcttt tagttgaatc
    36481 tacaccctta atttgaattg tttccatttc acaatatgaa tcctcatcca tattgacaat
    36541 agtaactgga tttaaaattc tctttccttc tccatcacct tcaccataat gtttttctac
    36601 atattttagg cgagctcctt tacgtaagaa aaatctatgt ataccattat gttcactatc
    36661 atcacaacca cagttatgta taccacaccc agcaattata acaacatctg cattttctcc
    36721 aatttcaaaa tcattatata ccatatcctg tacaccagcc tctgttacta ttactggtat
    36781 atgtacattt tctccttttg tatttggctt tactataata tctattccag gtttatcagt
    36841 tttaggaatt atagttacat tttcagttga atgtctctct actccttgcc catttttacg
    36901 tatattgtat gctcctaatg gagttccacg aagttcagca actttttcta aaagatttaa
    36961 atctattttg ttcatttaat ttgccttcct ttctaattaa ttcatgtctt tcattaattc
    37021 acaacttgaa ttaacttgac acatgatttc aggtaatata gcctcttttg ttccatggct
    37081 ttttactgaa ccatcttgta gaacaattat ttcatcagct aactctaata ttctttcttg
    37141 gtgagaaatt atgattatag tctgattaga ctcttcatgt attttcttaa aactttcatt
    37201 gagttttcca aagctccaaa ggtctatccc tgcttcaggt tcatcaaata tagaaacctt
    37261 taaatctcta gcaaaaagag ttgctatctc aattcttttc atttcccctc cagaaagaga
    37321 gttatcaact tcacgattta aatagtcttt tgaacacaat ccaacatctg taaggtattg
    37381 gcaacataca tcagtagaca atggttttcc atgagcaagt gtaagtaaat tttcaactgt
    37441 catacctttt attcttggtg gttgttgaaa tgcgtatcct attccttttt ttgctctttc
    37501 tgtaatacta agatttgtta tatcttctcc atctaaaatt atctgaccac tcgtagcttt
    37561 ttcaattccc ataataagct tagcaattgt agattttcct ccaccatttg gacctgtgat
    37621 aacaataagt tttcccctct caaatgaaag gctaacatca tttattattc ctagttcctc
    37681 attgttagac tcaacattaa aggaaagatt ttttatttca agcataatac ccctcttttc
    37741 tataaaatat tacattaata tccattcttt tattatatca gtaattttta tatatcagca
    37801 actctaagga gataaaatgt atattaaata ataaaacaaa gttattgaaa agtaaaaaag
    37861 atgagtttta tgtaaactca tctcagaaat ttagtatatc aacttatatg tatttaaaat
    37921 ttaaccttct atatactcta atattatttt ttgattatct tttaacataa tttcttcttt
    37981 tttagattct attccattct tttttatctt tacctcagct acaaaggcat cattaccttc
    38041 aaccatttct aatagttcat acgctttttt acgacctatt ttagttgcta tatcttttag
    38101 tactgccatt ttcttaaaca ttttatcacc tctactcaaa atttacactt aatttttaat
    38161 tatataattc taatcctaga ctagtttata ataattattg tctctaatta tatcagatat
    38221 tgagtaaatt taatactttg taaaattatt tatcctctct gaccaaataa tcatttccat
    38281 cttggtcttt aaaagaaaac atccttccat atggcatctc cattaattcc ccaacctcaa
    38341 cctcgttatt tgccatttgt tcataagttc cattaatatc tcttgtactt aaaattattg
    38401 atggatgaga tacatttatc tctttgtttt gcttcatcat tagattttta tcatacaaca
    38461 caaatgttgt aaattcattt ttacttggtg ctacttccac ccatttcata tttggatcca
    38521 tttccttttc ataagttact acaaagttca atttttctgt ccaaaataac tttgcatcct
    38581 cttgattatt tacatagaga gttatttttc ctattttatt tatcataaca atacccacct
    38641 ttattattaa ataaatacct aatatttttt atatttaata atatacccat atatattatt
    38701 ttctatagat atatatttct aatatttatc gccaaattat gtaattctgc tcaatatata
    38761 atttataata tccatactat tatagccttt atttatgtaa tttaatcacc ttatatatca
    38821 tacttataat tatgataata actacataaa aaatcacttc taaatagagt tatccatcta
    38881 aaagtgattt catatattct atgcaacttt gtgttttagc cactttgttc ctcttaatct
    38941 taaacaatat aaagtccctc taacaagcca atcagtatac atacctatcc aaattcctaa
    39001 cactccaaat tctaatacaa cccccaatac gtaacctgta aaaattctaa aaatccacat
    39061 acctattact gcagtcatca ttgtatatct agtatcaccg gctcccttta gccctgctga
    39121 taatacaaag gatataggcc atattaccat agctaaacaa tcacttcgaa ttaattgtgt
    39181 tgagatgtca attacactag cattttgagt atacatactt gaaatccaag gtgcaattgg
    39241 tataaatata gctcctacta taaataaaca aattgttgca aatttagtta aatataataa
    39301 agtactctta gctcctttaa tatctccacg tcctatatac tgtcccacca aggttgtagc
    39361 agacaaagct aaagcattcc caattacatt tattatggat gcaattgaca ttcctattgc
    39421 attggatgca attgctgatg ttcccatagt aactataaat acttgaacaa tcaatttacc
    39481 tgcattaaaa agtagttgtt caactccagc tggtattcct atattaaata tagacttttg
    39541 agtttcaaca tcaatcttaa atggaaatat tttacccata gatataaatt cgtttccttt
    39601 aaataaagct cttataatta ctatgcatcc aattattcta gctatagcaa tagatatagc
    39661 tgcacctgtt atgccatagg atggtgtttg caaatttatt cctagaggat ttaaatcaat
    39721 accatatata agtatatatc ccaatgttac atttactata ttcataaaca tagtcacata
    39781 cataggtttc tttacatctc cacaccctct taaaatacca tttgctattt gttgtgtcgc
    39841 aataaatgga tacgtaaata atgtaaactc tatgtataat tttgcatttg attttaccaa
    39901 ttcttctgcg gaaccataaa ataaattaat tacaccagtt ctaaaaaccc acatcaatat
    39961 tgttattgta aaggataata ttactccaga cactagagcc tgcttaatag tttcattcac
    40021 cttttcacta tctttttttc ctatttgttg agctacaaca acagtagctc caacagatag
    40081 tgcagcaaat acagatataa atatattgtt tattgaatca accattccaa ctgcagatac
    40141 agcttcttcc ccaatatgac ctgccatcat tgtattaaat actcctaaaa gcatgacaaa
    40201 cgtctgctct atcattatag gaattgctaa ctttataaca tttttcctta taaacatccc
    40261 tattcctctt ttccctcttt atataaattt aatttttaat tagtttatcg aactgtaaat
    40321 tgacaatgca aagtttagaa ttgtattgtt cgcattataa tatactgctt tcaaataata
    40381 taaatcttgt ttaatatcat ttgaacacag tatatcttta taattatctt atgtttatta
    40441 ttttttatgg ataccatatt taaaatattt attaatttaa tataaatatt ttccgttatt
    40501 attaaaagta gctatatttc gttaatattg tatcactatc gtgtagcaat aacaataagt
    40561 acattttata tattttttat aatattattt aatcatccaa acttttacca ctttttcaat
    40621 atataaaata ttacacttta gatgtaacaa aatcgcatcc atttaaatat tgtattttat
    40681 agactaattt taggatgtga tactttggtt aatttaaatg caaataatct aaatgtaaat
    40741 atggtttatc ctatttcttc cacagcaccc atacgtttca gaagatatac tgtttcatat
    40801 ttagaaaaca tggaaaatat ttatttaact atagcaacat actttgatac acttggttta
    40861 ggcacaatga atatcgacaa agtttatggt caatgggctt ggtttactga taatatatat
    40921 gatttaaatc tatttgtttt tgtaggaaat tatccttatc aaattgctaa aaacagatat
    40981 gatacatttg tagatatttt gccagtagct attacttcta ttgtcaatgg agatagagta
    41041 tttttaattt caaatccttg tttgttaaat tcaaaaatta cagttagatt tatatctagt
    41101 catcctactc ttaatagaac agttgattat ggcaatatta gagattttat tttttaaaac
    41161 tgcaacatga tgtgctatta aaaaataccc taaatttaat gatattatta aataactaga
    41221 atatttttaa ttggcacatc atgcctagct attataaatt cataatatta ttttacttaa
    41281 gataagtact gtattttatc tacttgtata tttttattta cctagtttct cagttctata
    41341 tcctatttct ttattagcta gcttataacc ttcttgtatc atttcttctc tcgttaatgc
    41401 actccctaat aaattgtcaa tactcagttg ctttctatca ctaaaatact tatccaataa
    41461 tgattcctct atatcttcct gatatgccaa atttccttca tgcattatat attttacatc
    41521 aaaaccttct ttatttaata cttttcccac caagatactt ctatgacatc ttataggttc
    41581 ttgcatagct cctaataaaa ctatcctata acccatttga caaccctttt ttaatctttc
    41641 tattccgttt aaaaaaatat cttcttttgc tactttctca aaatctgcat aaccttcttg
    41701 cgtatataca tctttattag ttcttttagc tccaaattct tttcccatgt atatatataa
    41761 aaatccggaa tttctaagag attcgttaaa tgcctcttta ttgtattgaa tattatattt
    41821 agaatatgga gtttctctaa tgtcaactac acaatttatg tcatattttt ttatcatatt
    41881 aataagctta tcatatggat aatttgaatg tcctattgcg aatatttcca tataaacacc
    41941 ctcctattct ttgaaattag tatctatata tgtagatacc cgatttactt aaaattaaat
    42001 aaagtattac tttaaatacc caatatcttt ttttcttgat attgtatatt tttttacttt
    42061 atatccttaa aaaaatatac aactttatat
//
LOCUS       DAEQAF010000026        42018 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.027, whole genome shotgun sequence.
ACCESSION   DAEQAF010000026 DAEQAF010000000
VERSION     DAEQAF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42018
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.027"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            98..2287
                     /locus_tag="KRN00_001469"
     CDS             98..2287
                     /locus_tag="KRN00_001469"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBH1827336.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2355..3122
                     /locus_tag="KRN00_001470"
     CDS             2355..3122
                     /locus_tag="KRN00_001470"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBH1827337.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYESIEKYGITPIHRKSFLKNIL"
     gene            3180..4196
                     /locus_tag="KRN00_001471"
     CDS             3180..4196
                     /locus_tag="KRN00_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1827338.1"
                     /translation="MEYNELLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4262..4510
                     /locus_tag="KRN00_001472"
     CDS             4262..4510
                     /locus_tag="KRN00_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827339.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(4686..5183)
                     /locus_tag="KRN00_001473"
     CDS             complement(4686..5183)
                     /locus_tag="KRN00_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH1827340.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNIN"
     gene            complement(5427..6491)
                     /locus_tag="KRN00_001474"
     CDS             complement(5427..6491)
                     /locus_tag="KRN00_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827341.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6494..7591)
                     /locus_tag="KRN00_001475"
     CDS             complement(6494..7591)
                     /locus_tag="KRN00_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827342.1"
                     /translation="MKLYMSVKTMLKGLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQNSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7605..8540)
                     /locus_tag="KRN00_001476"
     CDS             complement(7605..8540)
                     /locus_tag="KRN00_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827343.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINDLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSIIDKNDSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8669..9316)
                     /locus_tag="KRN00_001477"
     CDS             complement(8669..9316)
                     /locus_tag="KRN00_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827344.1"
                     /translation="MNKIKVLIVDDENLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9309..10472)
                     /locus_tag="KRN00_001478"
     CDS             complement(9309..10472)
                     /locus_tag="KRN00_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1827345.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10656..11000
                     /locus_tag="KRN00_001479"
     CDS             10656..11000
                     /locus_tag="KRN00_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBH1827346.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVANYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11031..12632
                     /locus_tag="KRN00_001480"
     CDS             11031..12632
                     /locus_tag="KRN00_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBH1827347.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFNKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12651..13751
                     /gene="dprA"
                     /locus_tag="KRN00_001481"
     CDS             12651..13751
                     /gene="dprA"
                     /locus_tag="KRN00_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBH1827348.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDISLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            13784..15871
                     /gene="topA"
                     /locus_tag="KRN00_001482"
     CDS             13784..15871
                     /gene="topA"
                     /locus_tag="KRN00_001482"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBH1827349.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16036..16821
                     /gene="codY"
                     /locus_tag="KRN00_001483"
     CDS             16036..16821
                     /gene="codY"
                     /locus_tag="KRN00_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBH1827350.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            16928..18193
                     /locus_tag="KRN00_001484"
     CDS             16928..18193
                     /locus_tag="KRN00_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBH1827351.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDIEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            18224..18994
                     /locus_tag="KRN00_001485"
     CDS             18224..18994
                     /locus_tag="KRN00_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1827352.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19103..19549
                     /locus_tag="KRN00_001486"
     CDS             19103..19549
                     /locus_tag="KRN00_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBH1827353.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19567..20760
                     /gene="nifS"
                     /locus_tag="KRN00_001487"
     CDS             19567..20760
                     /gene="nifS"
                     /locus_tag="KRN00_001487"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBH1827354.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGVAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            20814..21254
                     /gene="nifU"
                     /locus_tag="KRN00_001488"
     CDS             20814..21254
                     /gene="nifU"
                     /locus_tag="KRN00_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBH1827355.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21543..22622
                     /gene="mnmA"
                     /locus_tag="KRN00_001489"
     CDS             21543..22622
                     /gene="mnmA"
                     /locus_tag="KRN00_001489"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBH1827356.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22765..23003
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23071..25710
                     /gene="alaS"
                     /locus_tag="KRN00_001490"
     CDS             23071..25710
                     /gene="alaS"
                     /locus_tag="KRN00_001490"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBH1827357.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25735..25992
                     /locus_tag="KRN00_001491"
     CDS             25735..25992
                     /locus_tag="KRN00_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBH1827358.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26002..28173
                     /locus_tag="KRN00_001492"
     CDS             26002..28173
                     /locus_tag="KRN00_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827359.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDTMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            28379..28804
                     /gene="ruvX"
                     /locus_tag="KRN00_001493"
     CDS             28379..28804
                     /gene="ruvX"
                     /locus_tag="KRN00_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBH1827360.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            28882..29169
                     /locus_tag="KRN00_001494"
     CDS             28882..29169
                     /locus_tag="KRN00_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBH1827361.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29451..29909
                     /locus_tag="KRN00_001495"
     CDS             29451..29909
                     /locus_tag="KRN00_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH1827362.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30026..30763)
                     /locus_tag="KRN00_001496"
     CDS             complement(30026..30763)
                     /locus_tag="KRN00_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1827363.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            30980..32656
                     /locus_tag="KRN00_001497"
     CDS             30980..32656
                     /locus_tag="KRN00_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBH1827364.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            32862..33062
                     /locus_tag="KRN00_001498"
     CDS             32862..33062
                     /locus_tag="KRN00_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBH1827365.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33116..34279
                     /locus_tag="KRN00_001499"
     CDS             33116..34279
                     /locus_tag="KRN00_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1827366.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34490..34912)
                     /locus_tag="KRN00_001500"
     CDS             complement(34490..34912)
                     /locus_tag="KRN00_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBH1827367.1"
                     /translation="METKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(34933..35769)
                     /locus_tag="KRN00_001501"
     CDS             complement(34933..35769)
                     /locus_tag="KRN00_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1827368.1"
                     /translation="MRQEERTVCFDRELKIEAYRFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36067..36663
                     /locus_tag="KRN00_001502"
     CDS             36067..36663
                     /locus_tag="KRN00_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBH1827369.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGMYRIILSPIYTVLLKIVYLFV"
     gene            36693..37412
                     /locus_tag="KRN00_001503"
     CDS             36693..37412
                     /locus_tag="KRN00_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBH1827370.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKDKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37414..37953
                     /gene="scpB"
                     /locus_tag="KRN00_001504"
     CDS             37414..37953
                     /gene="scpB"
                     /locus_tag="KRN00_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBH1827371.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVATNE"
     gene            38115..38744
                     /locus_tag="KRN00_001505"
     CDS             38115..38744
                     /locus_tag="KRN00_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBH1827372.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38698..39126
                     /gene="ytfJ"
                     /locus_tag="KRN00_001506"
     CDS             38698..39126
                     /gene="ytfJ"
                     /locus_tag="KRN00_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBH1827373.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39374..39814
                     /locus_tag="KRN00_001507"
     CDS             39374..39814
                     /locus_tag="KRN00_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1827374.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            39830..41281
                     /locus_tag="KRN00_001508"
     CDS             39830..41281
                     /locus_tag="KRN00_001508"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBH1827375.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVFTTFDKINMISRNFNS
                     KENSIDTVTLIENNNLVNVCFVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNVATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41372..>42018)
                     /locus_tag="KRN00_001509"
     CDS             complement(41372..>42018)
                     /locus_tag="KRN00_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBH1827376.1"
                     /translation="SEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIICTLLVIIMA
                     LEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSLVCSVGELI
                     FSKNLGYEFPSLIYFIFIFSKCLIIYADIYMVDVRKFRVNRYALRDNLAICFIYFSFI
                     FLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKKKKSK"
BASE COUNT        16858 a         4447 c         7251 g        13462 t
ORIGIN      
        1 ataattaata tgaaaatata caaatatata aaaagtttgt ttagagttat agttaatgtg
       61 tgtattaatt taatactaat ttattggagg tttaaaaatg aaatacataa taaaaagaga
      121 tggtacaaaa gaacttttta gtaaaagtaa gattgaagat gctgtctata aagctagtat
      181 aaatagtgaa ggtggagtag atagagagtt ggcatatgat atatcaagaa aaatagctaa
      241 tgactataat tctatggaaa aatgcttatc cgtagaagaa atacaagata tagttgaagt
      301 actacttatg gaatcaaata gaaaagatat agcaaaacac tacatattat atagagaaag
      361 acgctctgaa ataaggacta aagcttggga gtttgatgaa ttacaaaaat caatatggaa
      421 gaacaagtat agacataatg gtgagagttt tgatgaatgg ataaagagaa tttcaaataa
      481 tagttcaaga atatcaaaac taataagaca aaaaagattt ctatttgctg gaagaatttt
      541 agcaaataga ggattacaga aagaaggaaa aaaagtaaca tattctaatt gttatgtaat
      601 agaaccacca aaagatagca tagaagatat atttgatact gcaaaaaaac ttgctagaac
      661 ttttagttat ggtggaggag ttggaattga tatttcaaag ctaagaccaa aaggagcgaa
      721 agttaacaat gctgcaaaac atacgactgg agcagtctct tttatggaac tttacagtat
      781 gacaactggc ttaattggtc aaagagggag aagaggagct cttatgattt ctatggatgt
      841 aaatcatcca gagatagaag actttataga tataaaaaca gatttggaga aggttactaa
      901 agcaaatatt tctgtaagag taacagatga atttatgcaa gctgtaagag aaaaaaagtt
      961 atataattgt acttttgaag ttgaaactac tggagaaaaa atagttaaga tagtaaatgc
     1021 ttatgattta tttaataaat ttgtgaaaaa taactgggat tatgcagaac caggtatatt
     1081 gttttgggat aaaataaaaa catataattt tatgagtgaa gataagaact tttgcttttc
     1141 aggagtaaat ccttgtgcag aagaaccact tccaagtgga ggaagttgtc tacttggctc
     1201 aataaacttg tcagagttta taatacaacc atttggtgaa catgctactt ttgatattaa
     1261 taaattaaaa tcttgcgtta gagaagctgt agtagcttta aatgatgtct tagatgaggg
     1321 attgaacttg catccattac aagaacaaag agatagtgta cataagtata gacagatagg
     1381 tttaggtgta atgggtatag ctgatatgct tataaaaatg ggaataagat atggttctga
     1441 tgaatcttta gaactatgtg atttaattgg taagactatg ttaaatgaag ctgtgaagca
     1501 atcagcacta attgctaaag aatatggaac atttagtgag tataaatatg aaaatatttc
     1561 taaatctaag ttttttatag aaaatctaaa tgaagacact aaggaaatgg ttaaaaagta
     1621 tgggcttaga aattcacaac ttttaaccat acctcctaca ggttctatat ctacaatgat
     1681 aggtattagt ggtggaatag aacctatatt taatctttca tatataagaa aaactgaaag
     1741 cttgcatgat gaggatgtgt attataaagt atatactcca attgttaaag agtatatgga
     1801 caagaaaggt attacagatg aagaatgttt accagatttt tttgttactg ctatgaatat
     1861 aggatatgaa gaaagaataa acatgcaaaa agtatggcaa aagtatattg atgcttctat
     1921 atcatctaca ataaatatac cttttgaaac tacagttgaa gatgttttca atatatatat
     1981 taaggcatgg gaggctggtc ttaaaggagt aacaatattt agagatggat gtaaaaggag
     2041 tggaatttta ataaatgaaa aaaaggaaga aaataataaa gaagataaaa aagaaaatag
     2101 taaaaaagaa tattataaaa ataataaaaa agaaaaagat aataaagatg aaaaagccaa
     2161 agaaataata aataaaaatt ttgaagaaga tgaaaaattt gtgtgtcctg agtgtggaag
     2221 tgaaggaatt gcacatacag gtggatgtag tatatgttta aaatgtggct atagtggatg
     2281 caattaaact ctaattaaaa aattttaata tatttaaaaa ttaaattttt aaaaacgaaa
     2341 gatgagggaa tggtatgcag gataaaagtg tgagggagat taaagaaata atagagactt
     2401 tagaagtaga aaaatatatg gaatatatag agctgttaag agttgatgaa agaaaatctg
     2461 tacaaggtct agctataaaa ctagcaaaaa agctggataa tattagaaaa gaagaagaaa
     2521 gattggaaac tataaatata tttgagaacg aaggctatga taaaggttat ttatatattg
     2581 gaggaattga tgaggcggga agaggaccac ttgctggacc tgttgtagct tctgttgtag
     2641 tatttaaaaa agataccaaa atagaaggtg taaatgactc taagaaactg agtgaggcaa
     2701 aaagagatga actttttgaa gtaataaaag aagaagcact agattatgga ataggtatag
     2761 taaacaatga agaaatagat gaatttaata tattaaatgc tacatatatg gcaatgaaaa
     2821 aggctataaa ttgtttaaaa aaagcaccgg attatttatt agttgatgca gcaacaatac
     2881 caggtattga catatctcaa aatccaattg tgaaaggaga ttcaaaatct atatcaatag
     2941 cagcagcaag tatacttgct aaagttacta gggatagtat aatgtaccaa tatgatagag
     3001 tatacccaga atatgggttt aaatctcaca aaggatatgg aactaaagaa cactatgaat
     3061 ctattgaaaa atatggtata actcctatcc acagaaaaag ttttttgaaa aatatactgt
     3121 aaatataata tgatataatg tatataatat aaattactat agttaatggg ggattaaaga
     3181 tggaatataa tgaattatta aaaagtgcta gagaaaattt aaatggaagt tgtaaagttt
     3241 gtaaggtttg taatggggtt gcttgtgcag gtgaagtgcc tggcatggga ggtaaaggaa
     3301 gtggttcttc ttttatagaa aatagcaaga gtttagaaaa agtaaaagta aatatgagag
     3361 taatacatga tgtatcaaat cctgatacat ctatagagat gtttggaaag aaaatgagtg
     3421 cacctatatt tgcagctcca gtaacaggaa ctactttaaa tatgggtgga aaaattaatg
     3481 aaagagatta catagaacca gtagttgcag gatgtgctaa tagtggtatt tatgcaatgg
     3541 ttggtgatac ggcagtagat gcttttttaa tggaaaattt agatgtagtc aaaaagtata
     3601 atggagctgg aattgtattt attaaacctt gggataatga aaatattata aaaaagataa
     3661 gattagctga agaagctggt gcatttgcag ttggagttga tatagatgcc tgtggtctag
     3721 taactttatc attacatgga aaaccagtac ttcctaaaaa tgttaaacaa ataaaggagt
     3781 tagtaaagtc tactaaacta ccatttatat tgaaaggtat aatgactgtt gaagatgctt
     3841 taatggcagt agaagcaggt gtggatgcaa tagttgtatc aaatcatgga ggaagagttc
     3901 ttgactgtac accaggagca tgtgaagttt taccaaaaat tgctgatgct gttaaaggta
     3961 aagttacaat acttgcagat ggtggagtga gaactggttt agacgtacta aaaatgatag
     4021 gtttaggtgc agatgcagta ttaataggaa gaccttttgt gactgcttct tttggtggtg
     4081 caactgatgg tgtagaaact tatgtaaata aacttcaatc agagctaagt agttctatga
     4141 tattaactgg atgtcaaact ataaaagata ttgatggaaa agttatatac aaataaaatt
     4201 ttatacaaaa aagaggaaaa atcattttaa tgtagaataa ttgtacaaag ggggaattta
     4261 tatgagtaga aaagcttatg aagaagcctt agtagaatta gaaaaattta ttgatgaaag
     4321 aaaagaaata attaaaagtg cggaggactg tattgataag tacatagttg acagaacgct
     4381 accttttgat tacaaagata aatgtgtgga atggcaacaa gagttacttg atattgcaga
     4441 ggcacaagtt ttagaagcaa atgaattaag tgtattatta caagagaaaa aagaacttga
     4501 agaagattaa attttattag ctaagagtaa atcagtaata tgatttactc ttagtttttt
     4561 ttatttgaat aaaatacatc tatctaattg agataacttt attaatatta gattaggcag
     4621 tttaaaataa gctaaagtag catggatgat tagtataaaa aataaaacca gtttaaaaaa
     4681 ctggtttaat ttatattctt tgaatttaat atatgttttt tcatttcctc taataccatt
     4741 gtataggatt tacattgagc agcagctaat tctgataaag caaatttttg agctttattt
     4801 aaaaactcct tatctgtgct acacaattgt tttgaactgt cttgtatcat aagcattttg
     4861 attaatttta caatttcaaa aacatctcct gaatgaaatt tatcttggta cagtttaagt
     4921 ctttcttttc tatcaaaaat ccatacacca tctgttttat taatagattg gataaaatta
     4981 tcaacatcat ttccatccat aactggacgt atgccaattc tatctgcatt tagaactgga
     5041 atcgaaattt taaggttact attaaaaatg acacttaatt catagtattt ttgcatctca
     5101 tgatttattt tctttgttac aatatcattt acagagcagg ctccctcttt tggatacatt
     5161 acactttcac caattttata catatgctag ttatacctcc aaattgaatt ttagatattg
     5221 caacttaggt acaatgcttt aattatctaa tgattaatat tataacataa ataacttgac
     5281 aagtcaaaaa tattaatata taatataaag tttagactta gtggtgtgtg aaactaaaga
     5341 gaaaaatata agataaaata atttaatatg ttgaaatatt cttttccaat tatataaaaa
     5401 tagatactaa ttatatttaa taattattag tttttagcaa aatctcttag tttaagactt
     5461 cctgcagtta caaatataat tccaattaat attagagcta ttatatttat taaaatacta
     5521 ccattgtttt taatagcatc tatagtccaa taaaatggtg tgaactttga aagattagtc
     5581 ataaaggata atttatccat tgatggtatt agactagaga tagatatagc tagacctatt
     5641 aaagaataaa atgtagatat aagacttata gaactttcat ttttaaatac tctagctacc
     5701 caaaatacaa atccagtgga aacaaaacta tttgctagta caatcatcaa tacattcaga
     5761 ctcaaattaa agtcttctat aattgaaaaa cataatagag caaaagtgta tacaattgat
     5821 tgaataaaaa atagtcctaa aaatatactg aaaattattt ttatatcttt attatctgta
     5881 gagataagtc tttttagcac atttgatttt tttaatgtaa ataaatcaga agcaagatgt
     5941 gccgcattaa tatacataaa atagcatatc aagaagacta ctaaaaatga acctttattc
     6001 ttatctggtt tgttatcaat tatatttgtc tttgtcaatt tatcatctat atttttatcc
     6061 actttcaatt ttaacgattt agtaataaaa gattctattt gtgattctgc ccaaagacta
     6121 ccaccaccat tttcaatttt aaagcattta actacaggtc gttgtaattt atctatacta
     6181 tttgaaaaat ttttatctaa aacgaataca gcagaaacct tattattttt taatagattc
     6241 atagccttat cttgttcatt taatctaaat gaattttctt ttaatttaga actatttatt
     6301 aacttatgtt catactttcc tgaagagtca gatacaattg ctactggaga aaagtacatt
     6361 gattgatttc ccgagttgtt gataaaaaaa ttaagtgaaa aaattagtat aataggaagc
     6421 ataaccatat taattaaaag agtatgattt tttagatatc tttttatatt tgcaatagtt
     6481 aatctaatca ttattaaacc tccctccatt tatatttttc ctttacaata gcaagtgcaa
     6541 ttaatattgt agagataatt aaacatgtga aaattaaatc tcctattgaa tctatagttt
     6601 taaatgtttc ataattacta aacaattctc ctattaaata ggtaggagat aaacttgtaa
     6661 gcttagtaaa tgtatcactt atcatactga agatacctcc aaaaattgtc tgtaaaaaga
     6721 gtaatgcata aactattgct gtaccgtatt ttttactaaa aaagctggtt acaaaggtag
     6781 atattgaagt cataaaataa gatgataaag cacaaagtag gagcaatatg gcaaaattac
     6841 ctttaaatgt tattccaagt attctaaaga ataaaacata taataataag aatataaatg
     6901 aataaatcca taaacctaca aagtcataaa ttaagaattg tactctagtt ataggcatag
     6961 aataaagtct ttttgaaagt ccctttgatt cacttatata atttgacaaa atattgttca
     7021 ttataaaaat tattacaaga aatcctagtg aaactaaagc aaagtattca taagagttct
     7081 gtttaacatt gttatttatt atagaagtat caatagaatt tttattaaat aatttagaaa
     7141 aatcttctga acttattttc tgagaattat ttaaataaaa tttttcatgg taagtatcta
     7201 atatatcttg aagcaatatt gcaatatcat cacgagttcc aagtttttct atgtttagag
     7261 tatttgattt ttcatttaat aaactactct catagccttt aggtatagta agctttaatt
     7321 ctgccttaga atcatctttt ttaactgtta atatataaga taaatcattt ttcaaatact
     7381 ttgtcaaatc atttgataat cttgtgttat ctttgtcata tataacaatg ggggtagatt
     7441 ctgtttttat agggttttga aacatgcttt ctgtaaccat accaagaaac caagataaaa
     7501 tcagaggtaa agctaaaaaa tatattaaat taagtataaa ggagcttttt aaacccttta
     7561 gcatagtttt tacactcatg tataatttca taaaatcacc tccattagtc ccttaaattt
     7621 ttgcctgtta gatttaaaaa tacatcttct agactaggtt cttcataaga aattttcatt
     7681 atttttgaat cgtttttgtc aattatagag agtatatctg taagttgtaa ttttttatct
     7741 atatccaatt ctaataatga attattttct aaaacagata taacaccttt agtatttttt
     7801 aaatcaaaga taagttgggc atttatattt tttatttcca taatcaattt tgtatttgta
     7861 gatacgagtg attttaaata atcattatct ccaaaagcaa tttctttacc ttcatccata
     7921 ataaaaattt tagaacaaag gtgttcaact tcttccatat aatgggaagt atatattaca
     7981 gtagtttcat gttttttaga tatatctttt ataaaattga aaatatgatt tcttgattgg
     8041 gggtctacac ctacagttgg ttcatccaat attaatattt taggatgatt taagagtgct
     8101 attccaatat ttaatctcct ttgcatacca ccagataatt ttttgacctt tttctttttg
     8161 acttcagtaa gacctgtaac ttctaatgct tcaatgattc tttctttaag tagttttccc
     8221 tttaaaccgt agaaagctcc aaagtactct aagttatcaa aaggagtaag agtttctata
     8281 attgctaatt cttgtggaac taaccctatt atagactttg cttttatata atcttttgat
     8341 aaatctaaat cattgatttg aatactacca ctatttggta acataagatt tgtaattata
     8401 tttataagtg tagatttacc tgcaccattt gggccaataa gtccaaatat ctcacctttt
     8461 ttaacagaaa agctgatgtt atcaagtact aatttatcat taaatctttt tgttatatta
     8521 tttactctga ctatatccat agtaatccct ccaaaataat tttgtataag ttaaaaagct
     8581 ataatattat aataaagaat tgtgaattat aattctatta ctataagtca ctaaaaaaag
     8641 tgacttaagt cactttatat ttttagattt attctattac aattttattt ttgaaagcaa
     8701 agattgctag ttgagttctg tcacgaagtt ctagtttagc taaaatatta gttatgttat
     8761 tctttattgt accttcagat aagaatagtt cttgacttat ttctttatta ttaagtccat
     8821 ttgcaattag tctaattata gatatttctt tttctgttaa attgtacatg tcataaagat
     8881 gctcttgttt aaccgttttt tcagaggtca tgattttttc agctacactt ttatcaagca
     8941 caatattgcc aaaaaatgaa gaacgaatcc cttcatgcaa tacttcatca gagctatctt
     9001 ttaaaaggta tcctgaagca ccaaacttca tagcatcttt tatatattca tcatcattaa
     9061 aagttgttaa aattaataat gttatagaat tattatattc ctttataagc cttgtaccta
     9121 gaaccccatc acatactttc attcgtatat ccataagaac tatgtctaca tcattcattt
     9181 tacaaaattc taaagcttca tatccattag aagcatctcc tacaatttct aaatcattat
     9241 aagatgataa tataatttta agaccttttc taattaaatt ttcgtcatct actataagaa
     9301 ctttaatttt attcaaaaaa atcaccccct gaaaatttag gaaaagaagc tctaattgtg
     9361 aaaccattat tagaattatc aaattcaact ttaccattta attcatatat tctctcattg
     9421 atactattaa gtccatttcc tttttttata ttgccacatc ctataccatt atcactaata
     9481 gtaattataa gatttgaagt attgaatgta ataaaaattc tgatttcagt tgcctttcca
     9541 tgcctagatg agttggaaag ggattcctgt ataagtctat ataaagctat agattgattt
     9601 ctggataagt tccaagtatt ttttgaaata gttaatttaa cattaatatt tgtaagctta
     9661 ataaagcttt taactaattc tttgatttta aataaacttt ggtaattttc atattcaaca
     9721 ggttttaact cagatatagc ccttcttaca tcttgaaaac tttcagttac aaattctcta
     9781 agttcatgta ctaagtcata aattagaggt ttgtctttta agagtttttc tatagcattt
     9841 aattgtatta ttgttgtaga aagagaatgt cctacactat catgtatttc tcttgatatt
     9901 cgatttcttt cttttaaaat tgctaattct tctatagaac ttgcataagt ttccaaatca
     9961 gcattaactt tttttaattc atctttagaa attctaagct tatcataaag attttgactg
    10021 tataattttg ataaattctc attttctata tatatagaaa gtacagttat aattagcaat
    10081 atagagcttg actccagtgc caaatatata tttttatcta aactaataat aagagaagat
    10141 attataacaa aagagaacaa tatgtactta tatttttcct ttattaaaaa tgatatatct
    10201 aatattaaag gaacaaagta aatcgaatta aaagtttttg tataattaca aagtataaaa
    10261 attaatataa gttctaaaaa gtaagaaata agtataaatt tattctcatt tgataaagaa
    10321 aaaaatctaa cttgattatt tattataatt agaaataata ttatcatagt tatgaccgga
    10381 tacaatgtat tttcaacatt tttcaaatag cttacaacta atataaataa agataaatat
    10441 cgtataaaag caactaattt ttctctgttc attaaaggca ctcctccaaa aaaataaact
    10501 tttcctatga aaactagaat aatatcataa aagaataaag tcaatagaag tatttattaa
    10561 tattgatgga aataaaatca atccaaaaac ttgaatagta aaattgtata ctgaccataa
    10621 tttaaaagtg aaaatttaat gtattggagt gaataatgaa taataaagaa aaaggtgatt
    10681 ttggagaaaa agtagcagtt aattatttgc tatcaaaagg agcaaagata ctagaaaaaa
    10741 attacagatt aaagataggg gaaatagata taatagcaaa aatggaagat gaaattatat
    10801 ttgtggaggt gaaatcaagg tctaacataa agtttggcta cccttgtgaa tctgtaagct
    10861 tcaaaaaaag aaaaaagata attggagttg caaattatta tattataaaa aataacttaa
    10921 ataacactcc cataagattt gatgttatag aggtatattt attagaaaaa agaataaatc
    10981 acataatgaa tgctttttaa aaaagataat gtttttggaa aggattaaat atgttaagta
    11041 ttattaattc aagcaactta gtaggaatcg acagcttttt agttaaggtt gaagtagatg
    11101 taagcaatgg aatacctagt tttaatattg ttggtcttcc aggcaaagaa attaaagaag
    11161 caagagaaag agtaaagtca gcaattctta atagtggata taaatttcca agcacgagaa
    11221 tagttgtaaa tttatcacca gcagatataa aaaaagaagg agctttttta gatttatcta
    11281 taagtatagg ccttttaaga gagttaataa aaaaagatga aaattacata agagaaagta
    11341 tgtttatagg agaattatca ttagatggga aaataagaaa agtaagaggt atattgccca
    11401 taattatggg tgcaaaaact cagaacataa aacgtatttt tataccaatt gagaacataa
    11461 aagaaagtct atttgtagat gaaattgata taattcctat taaaagttta aaagaatgtg
    11521 tcgatttttt aaacgaagag ataaaagtcg ataaagtaag gataatgtct tttttggatg
    11581 ataagtcaag aaaagagaac gaagaattag aaaaagataa tagttatata gattgcaaat
    11641 atactaagat taataatgaa gaaagtaaat atgatgaaga ctttaaagat gtaaaaggaa
    11701 attattttgt aaagaggagt gcagaaattg ctgctgctgg aaatcataat atgtttatga
    11761 ttggacctcc aggctcagga aaaactatga ttgcaaaaag agtaaggaca attttaccag
    11821 atataagtgt agaagaaatg atagaagtaa gtaaggtcta tagtatattg ggtatgataa
    11881 atgaaactaa aggaataatt gataaaagac cttttagagc acctcatcat acaactacaa
    11941 agcaatcttt aattggagga ggaatggatg caagacctgg agaaattgct ttagcacata
    12001 gaggtatctt atttttagat gagatagccg aatttgatag aaaaatactt gagactttaa
    12061 gacaacctat agaagatgga tatgtaaata tatccagagt aaagtacagt gcaaaatatc
    12121 cttgtagagt actgttagtt gcagctatga atccatgtcc atgtggttat tatatgtcag
    12181 agacagagtg tagatgtaga agtaacgaaa ttgatagata cataaataaa atatcaggtc
    12241 cattgttaga taggtttgat atttttgtag aagttaattc tataaaatat tcagatttta
    12301 attctttaaa acaagaagaa agctctcaaa aaataaagag aagagtagaa aatgctagaa
    12361 aaatacagat aaatagattt aagaaggata atataaaaaa taatagtgaa attaaagctt
    12421 acaatttatt taaatattgt aaactggaaa aagaagcttc aaaaacggct gagatgatat
    12481 ttaataaata caacctaagc agtagaagtt atacaaaact tttaaaaatg gcaagaacaa
    12541 tagcagattt agaagaaaga gacttgataa attcacagtg tattatagaa gctttttcat
    12601 ttagaaaggc ttattatagt tattttaaat agttttttga ggtggatttt atggaaaaaa
    12661 gagatactta tttatggtta aaatcaattg gtggaataac aacaaaaaca attgaaataa
    12721 tagaaaatga aatagtaaat attgaagata tatttgattt ttctgaaaaa gaaatatata
    12781 atttaaaaaa tataagcttg aatattagaa aaaatatagt aaaatataga ggtcacgctt
    12841 atttagaaaa tataaaagaa ctactttaca aaaaagcgat taaatatatt tgtaaatatg
    12901 ataaagaata tcctgaaaat ttaaagaata tatacaacgc tccaaagtta ttattctaca
    12961 aaggtgacat aagtttagtt aataataatt ttaatatagc tatagtaggt tcaagaaaac
    13021 ctacagccta tggaattaat tgtgcaaaaa caataagttg tcaactatcc caatatggag
    13081 ttaatatagt aagtggatta gctataggaa tagatgcata ctcgcacata ggttgtatga
    13141 gtggaaaatc taaaactata gcagtacttg gttcaggagt agacaatcct cttccaaaac
    13201 aaaatttaca tttatcaaat aaaatattag aaaatggggg attattatta tcagagtata
    13261 atattaactc gacagtagcc ccgtaccatt tttctaatag aaatagaatt atcagtggtt
    13321 taagtgatgg agtagttgtt gtagaagcag caataaaaag tggtgcacta atcacagtag
    13381 attttgctct tgaacatgga aaaaatgttt ttgcaatacc tggtaatata aattctcaaa
    13441 tgagtagagg ttgtcataaa attataaaag aaggtgcaaa attaattgaa aatatagatg
    13501 atattttaaa tgaatataac atatttaata ttattgataa aaaaataaat caaaaatatg
    13561 ataatataag tctaaatgcc aagtctaagc aaataattga agctataaaa agagaaggaa
    13621 acttgcatat agatagtatt tgtgattata ctggtataga aataaagtat gtaaattcaa
    13681 taatcaatga attagtacta aatgagttag tagtagaaat gaataataaa acgtacagtt
    13741 taaatgtata aattaagatt aggtagtggg ggtgtatggt tttatggcca aaacattagt
    13801 catcgtagaa tcgcctgcaa aagctaaaac tatagaaaaa tttttaggga aaagtcatta
    13861 cacagttaaa gcatcagttg gtcatgtcag agatttacct aaaagtaaat taggtgtaga
    13921 tatagaaaat aattttgaac ctcaatatat aaatataaga ggaaaaggcg atgtaataaa
    13981 agaattaaaa aaagaagcta aaaaatctaa acaagtgtat ctagcaactg accctgatag
    14041 agaaggtgaa gctatatcat ggcatttagc tcatatacta aatttagatg aatctgagga
    14101 ttgtagaata gagtttaatg agataactaa ggatgcaata aaaaaagcaa ttaaacatcc
    14161 taggaatatt gatataaatt tggttgatgc acaacaggca agaagagtgc tagacagact
    14221 tttaggttat caaataagtc ctatattatg gcaaaaggtt agaaaaggtc ttagtgcagg
    14281 tagagtgcaa tctgttacaa caaagttaat ttgtgacaga gaaaaagaaa taaaggcatt
    14341 tattccaaaa gaatactgga caatagatgt tgaggctaag acagtaaaag acaaagatat
    14401 aactttgaaa ttttatggta aaaatgatga aaagattgaa ttagaaaatg aagaagctgt
    14461 aaatgaaata ctaaaagaaa tggaaggtaa agatttaaag gttgagaaga tagaatctaa
    14521 atcaagacgt aaatcagctc caaaaccatt tacaacaagt atgcttcaac aagaaggagc
    14581 aaataagtta ttttttacta ctaaaaaaac aatgatgata gcacaagaat tatatgaagg
    14641 tatcgacata gaaggtgaag gtactgttgg tcttatatca tatataagaa ctgactctaa
    14701 aagaatatct gatgaagcaa aagaaaaagc taagggctat atcgtaaaca atttaggaga
    14761 aaactactat aaaaacactg gtgataaaaa agaaaaaaag gatactaaaa aggttcaaga
    14821 tgcccatgag gcaataagac caacctcagt tgatagaact cctgagagta taaaagcctc
    14881 attgagcaaa gaccagtaca agttatacaa tttaatttgg agaagatttg tagctagtca
    14941 aatggaagat tcagtgtttg atatactaaa tgtagaatgt aaaataggcg atattgtatt
    15001 taaggcaact ggttcaaaaa tgaaatttga tggttatacc aaggtatata atttttcaga
    15061 aagagaagac aaaattttac caagtataga aaaaggagat atattaaata tagaaaatat
    15121 attgccagac caacatttta cacaaccacc agcaagatat acagaagcta gtttagtaaa
    15181 aacactagaa gaactaggta taggtagacc aagtacgtat gctccaacaa tagctactat
    15241 actgaataga gagtatgttg aaaagcaagg aacaagtcta tgtccaacag aacttggaat
    15301 aatagttact gatattttgg aaaataattt ccataaattt atagatgtag attttactgc
    15361 tgatatggaa agtaaacttg atgttataga agaaggcaat acagattgga aaaagattgt
    15421 atcagaatca tatgcaccac ttaaagaggc tattgaagaa gctcttgaaa atatagaaaa
    15481 agtaaatatg gatgaagaaa ctgatgagat ttgcgagaac tgtggttcta atatggttat
    15541 caaatatggt agatttggaa agtttatggc ttgtaaaaac tatcccgatt gtaaaacaac
    15601 tagaccaatt atgaataaaa ttggtgttaa atgtccaaaa tgtgaagaag gagatattat
    15661 acttagaaaa tctaaaagag gtaaagcttt ttatgggtgt tctaattatc caaactgtga
    15721 ctttgtagct tggaataagc caacaggaga gttttgtgag aagtgtggtt catatatggt
    15781 tgaaaaagtg actaaatctg aaacaaaaac agtgtgttct aataaagaat gtaataaaga
    15841 gacaaaagag cataatgacg gaaaagagtg aaaattgaaa aaaatcacat aattctcttg
    15901 aaaaaggttc caatctatga taatctttca agtgtaaaca actaatagaa aaataaattt
    15961 tcattaaatg tgaaaataat attagaaaat ataaaaggtt attaaaaggc ctaaatttca
    16021 tgaggagatg attaaatggc aagtgaagtg ttacaaaaaa caaggaaaat aaataaaaca
    16081 ttacaaacaa gtggtggaag cagtgtctct tttgatttac tggccggagc attgggcgac
    16141 gttttaagtt ctaatgttta tgtagtaagt gcaaaaggta aagtactagg tcttcattta
    16201 aatgatgttc aagacagttc agttatagaa gatgagtata ctaagcaaaa gaaattttca
    16261 gatgaatata ctcaaaatgt gttaaaaatt gatgaaacat tagaaaattt aaatggtgag
    16321 aagatattag aaatctttcc tgaagaacat ggaagattac aaaaatatac tacagtagtt
    16381 ccaatattag gaagcggtca aagattagga acattggtac tttcaagata ttcaaattca
    16441 ttcaatgatg atgatttagt aatagctgaa tacagtgcaa ctgttgttgg tcttgaaata
    16501 ttaagagcaa taggtgaaga attagaagaa gaaatgagaa agaaagctgt agttcaaatg
    16561 gcaataggca ctctgtccta ctccgagctt gaagcagttg aacatatttt tgctgaattg
    16621 gatggaaaag aaggtctact tgtagcaagt aagatagctg atagagttgg tataactagg
    16681 tctgtaatag taaatgcact tagaaaattt gagagtgcag gtgtgataga atcaagatca
    16741 ttaggtatga aaggtactca tataagaata cttaatgaca aacttacaga tgaattaaaa
    16801 aaattaaaaa acaatcaata atctatattt tataggttta gattagaaaa ggtatctatt
    16861 tcaaatagat acctttttta gacgaattat taaggtaatg ataagtatat taaaaaggag
    16921 tgagaaaatg cctttagcag ataaaataag accaaaaaca atgaatgatg taataggtca
    16981 aagtcatata ataggtaatg gaaaaatatt gtctaagata ttacaatcta attttttacc
    17041 aaatatgata ttttttggtc ctcctggtgt tggtaaaact acagtagcgg aaataatagc
    17101 agaaagaagc aataaaagct tctataaaat aaatgctact aattcatctt tagaagatat
    17161 aaaaaaggtg atatcagagc ttggaagtat aaataatgta aatggagtcc tattatatat
    17221 agatgaaata caaagtttta ataaaaaaca gcaacaatca atattagaat ttatggaaaa
    17281 tgggagtata actttgattg ctagcactac agaaaatcca tatcattatg tatataaagc
    17341 tcttttaagt aggtctactg tatttgaatt taaaccttta gaaaaacttg atatagaaaa
    17401 aggactgaaa agagctgttg aagtattaaa tgaagatagt tatatggata ttgagtgtaa
    17461 taatgatgct attgaagata tagcaattct ttctgatgga gatatgagaa gagccttaaa
    17521 tattttggaa gtggtagtct attcaactaa accaaataag gataatataa cttatataga
    17581 ttcagatgta ataagggcat ctacatttaa taaaattata aactatgaca aaaatggtga
    17641 tagtcattat gatattttaa gtgcatttca aaaatctata agaggaagtg acccacaggc
    17701 atctatacac tatctagcaa gacttataaa aggtggggat ttgataagta tatgtaggag
    17761 acttttagta atagctagtg aagatatagg tttagcttat ccaaatgcta ttgtaattgt
    17821 aaaggcatgt gtagactcag ctatgcaact tggatttcca gaagcgaaaa taccattagc
    17881 agaagctact attcttttgg ctacatctcc aaagtctaat tctgcatgta tagcaataat
    17941 gaaagctatg gatgaactgg ataaagagtt tgttaaggat ataccaaata gtataaagga
    18001 tgctcactat tctggttcta aagaaatagg taggggttgt ggatacaaat atcctcataa
    18061 ttttaaaaat cattatgtaa agcaacagta tttaccagat agcataaaag atagtattta
    18121 ttacatacca caagaaaata aaactgagaa aaatataaaa aaatatttag aatatctaaa
    18181 tagtgatttt tagactgaac tttatgtatc gggggtagat attatgatta taaaacttaa
    18241 ctcaacttat cacagtagag ttatgaaata cttaaaaaaa gaacctgagt acaatttgtt
    18301 tataataggg gatattgaaa gatatggata tggaaataat tttttaaata tatgggcaga
    18361 tgtgggtgaa catggtgaaa taaaggcaat attacttaaa tattttgaat ttatgatgtt
    18421 ttattctgat ggagagtatg atgttgaagg tttttataat ctacttcgta atactaatta
    18481 cgaagaaata tctgggaaaa tatgtgctgt agatgcttta gcaaagagat taggacttaa
    18541 taatttaaag gtagttgatt tttgcaaact tcaaactaaa aagtttttga tagataataa
    18601 ttgtaatgca aaggttaaga gaattagact tggaaatcta aaaaagacag tgaaacttta
    18661 tgacttaata gatgaatttc acagtacaac tttagagaat ttaaaaaatg gactaaggac
    18721 aggtagagga tattgtatag agattaacaa acaggtggtg tcaatggcaa agagtacttc
    18781 agaaaatagg actcatgcaa tgataattgg agtaggaaca catcctaaat atagagctaa
    18841 aggacttgct acaaaatgcc taattaaact atgttcagag ttactgagag aaaacaaaat
    18901 tccttgtttg ttttatgata atgaagaggc tggaaagata tataaaaaac taggatttga
    18961 aaacattgga aaatggggaa tttattcaaa ataaaaaatt aaaattaatc ttgacaaaat
    19021 tagtagggta taataaaatt atcttgaaag taattcctac taaaacagta tgaattagat
    19081 ttctatatag aggtgataat atatgaagtt gtctactaaa ggtagatatg gactaaaagc
    19141 aatgtttgaa ttagcattaa atcaagacaa tggaccagta tcattaaaat ttattgctaa
    19201 gaagcaaaaa atatcagatc agtacttaga acaaatattt tcatctttaa aaaaatcggg
    19261 tctagtaaaa agtgtgagag gtgctcaagg aggttatttg ctttcaaaga atgctgaaga
    19321 cataacagta ggagatatac ttgtagtatt agaaggacca gttgcattat ctgactgtgt
    19381 actagatgaa gatgtatgtg aaaactcaaa catgtgtgta acaaaaatag tttgggaaaa
    19441 gatgaaaaag ggtatagaag atgttataga ttcaattact cttaaagata tgataaatga
    19501 ctataacaaa aataaattag aaaatgatat aacaaatatt aaaaaataga tttggagatg
    19561 aatgtaatgg aaaaaagaag attgtatatg gattattctg caacaacacc tattaaaaaa
    19621 gaagtattgg atgcaatgat gccataccta acagattatt ttggtaatgc atctagtttt
    19681 cacacattcg gaagagaagc aaaagatgct ttggataaag caagagaaca agtagcagcc
    19741 cttataaatg ctgaacctag tgaaatatat tttacagcag gtggttcaga aagtgataac
    19801 tggacactag agggcgtagc ttatgctaat aaaaacaaag gtaatcatat aataacttca
    19861 aaaatagaac accatgcaat acttcataca tgtgaatact tagcaaaaca tcatggattt
    19921 gaaataactt atttagatgt tgatagcgaa ggaaaagtag acttaaagca actagaagat
    19981 tcaataaaag atactactat acttataagc ataatgtttg caaataatga aataggaact
    20041 atacagccta ttaaagaaat atccgaaata gctaaaaaac ataagatatt attccacact
    20101 gatgcagtac aagctacagg taatattcca gtagatgtta aagagttagg aatagatttg
    20161 atgagtatgt cttcacataa aatatatgga ccaaaaggtg taggagcttt atacataaga
    20221 aaaggtgtaa gacttcataa ctttgtccat ggtggagcac aagaaaaaag caaaagagct
    20281 ggtacagaaa atatacctgc aatagttgga tatggaaaag cagcagaatt agctaaggaa
    20341 aatatgcaaa atcatgtaga aactttaact cgtcttagaa ataagttaat agatggtgtg
    20401 ttagaaagaa taccttacac aagagtaaat ggtagcttag aaaatagatt gccaggaaat
    20461 gcaaactttg cattccaatt tatagaaggt gaaggaatac ttttattatt agatatgtta
    20521 ggaattgctg gttcaagtgg ttctgcatgt acttctggtt cattagaccc ttcacatgta
    20581 cttcttgcaa taggtttacc acatgaaata gcacatggtt cattaagact tacagttgga
    20641 gattttacaa cagatgatga tatagattat atactagaga acttaccaaa agtaatagaa
    20701 agacttagaa gcatgtcacc actttatgat gatgcgaaga aacaaggttt agtaaaatag
    20761 acataaagat aaagcataaa aaatagacat aaattgagta ggaggaaaag ataatgcaat
    20821 atagtgataa agttatggaa cattttatga atccaagaaa tatgggagaa attgataatg
    20881 caagtggtgt aggtgaagtt ggaaacccta catgtggaga tataatgaag atatttttag
    20941 acatagatgg agatgtaata aaggatgtta agtttaaaac atttggctgt ggttcagcta
    21001 tagcaagttc ttctatggca actgaaatga taaaaggaaa aactataaaa gatgcattag
    21061 aacttacaaa taaagctgtt gcagaagctt tggatggttt accaccagta aagatgcatt
    21121 gttcagtttt agctgaacaa gctgtaaaag cagctcttat agattatgct caaaagaaca
    21181 atatccatat accagaattg gatggatatg ttatagatga tgctcatgac catgatgttg
    21241 aagaagaaga ataaaaataa gtgattgtgt tatgagaagt ttacaatgat taaaaagaag
    21301 tactaatgat ataattagga cataaaaaat agctgttttt aaaatggcta ttttttattg
    21361 cctaaattaa gtattttaac ttgatttaga ggttaattag ttaacaaaat aatccataag
    21421 attcaaataa taaagatgat tattttttta gaaaatagaa caagctatat tttaaataag
    21481 tacaatactt gctctatatg gtataataat aagtaatgca aaagatgagg tgaaatttgt
    21541 ttatgaataa aaaagtaatg ataggtatga gtggaggagt tgatagctct gtagctgcat
    21601 atcttttaaa acaacaagga tatgatgtca ttggtgttac tatgaagttg tggcaagatg
    21661 atgatgttgt tgaaattgaa ggtggttgtt gttctttatc tgctgttgaa gatgctagaa
    21721 gggtagcaaa taaaataggt ataccatttt atgttttaaa ttttagagaa gtgtttaaag
    21781 aaaaagtaat agattatttt atagatgaat atttggaagg aaaaactcct aatccctgta
    21841 tagcttgtaa taaacatata aaatttgatg atttttataa gaaggctaga caaataggtt
    21901 gtgattatgt agctacaggt cactatgcaa agatagaaaa ggatgaaagt acaggaagat
    21961 atttgctaaa aaaatctgtt acagataaaa aagaccaaac ttatgcactt tataatctta
    22021 cacaagagca actagagcat actttactac caataggtga ctatgaaaaa gatagagtaa
    22081 gagaaattgc taaggaaatg ggtatggcag tacacaataa gcctgatagt caagaaattt
    22141 gttttgttaa agataatgac tatgcaaatt atgtaaaaaa acattctaaa aagcgtattg
    22201 aagaaggttt ttttgtagat actaaaggca atatacttgg aaaacataag ggtatattat
    22261 attatactat aggccaaaga aaagggcttg gaattacttt tggaaaacca atgtttgtaa
    22321 tagacataaa tccaataaat aataccatag ttcttggaga caatgaagat ttatttaaaa
    22381 aggaacttat tgctaaagat gttaacttta tatcaataga tacgttagaa gaacccttaa
    22441 gagttcaagc caaaataaga tattcagcaa aaccatcacc agctactatt catagagtag
    22501 gagaagatac tattaaaata gtttttgatg aagctcaaag agctattact aaaggtcaat
    22561 ctgtagtaat gtatgatgga gatattgtag taggtggagg tataatcgag aaaagtttat
    22621 aaaaacatct aaaaaattaa aaaaataaac aataaagtat attaagagta aataaagttt
    22681 ataaaataaa tttattgtat atgaaaatat agtattgatt aattttgtaa aatttagtaa
    22741 tataattagt atattaatta aaaaacaaat acagtgataa ggaatagtaa aatatttgat
    22801 gtcttacaga gagagggaaa tgctggaagc ccttagaata tgatatttga agcagccttt
    22861 tagtagcaat cttgaacaat ttatctttta taaagaagat ttaagtagag attgacggta
    22921 gttacgttat agctaaggtt ttccgaagat atcatacttt gtatgataat tagggtggta
    22981 ccgcgattgt cctcgcccct ataaatttat ttatagggac gaggtttttt atttaaacga
    23041 aaaaataaaa tttattagga ggaacatgat atggaaaaga tgggattaaa tgaaataaga
    23101 agtaagtttt tagaattttt tgagtcaaaa ggtcattatg tagcaaatag ttattcttta
    23161 gtaccaaaca atgataagag tttgttactt ataaactcag gtatggcacc tttgaaaaac
    23221 tacttttcag gtgtagaagt acctccaagt gtgagaatgt gtacatctca aaaatgtata
    23281 agaacaggag atatagaaaa tgtaggtata actgcaagac atgctacatt ctttgaaatg
    23341 atgggtaact tctcatttgg agattacttt aaaagagagt caatcaaatg gggatgggaa
    23401 tttgttacag aatggctaaa tataccagaa gataagatat gggtgactgt atatgaagaa
    23461 gatgatgatt cttatgatat atgggcaaaa gaaatgaatt tcccagaaga aagaatggtt
    23521 agacttggaa aagatgataa tttctgggaa ataggtacag gtccttgtgg tccttgttca
    23581 gaaatatatt ttgatagagg agaagaatat ggatgtgaca atccagactg taaaccaggc
    23641 tgtgattgtg ataggtattt agaattttgg aaccatgtat ttactcaatt tgatagagat
    23701 gaagaaggaa attatagtct attagaaaac aagaatatag atacaggtat gggtcttgaa
    23761 agaatgggat gtattatgca aggcgtagac actatctttg aagttgatac aattaaatct
    23821 atactagaag cagttgagaa gttaacagga gtaaaatatg gagagaatcc aaaaaatgat
    23881 atatcaataa gaataataac tgaccacata agagctgtaa cattcttagt tagtgatgga
    23941 gtgcttccat caaatgaagg aagaggatat gttcttagaa gactccttag acgtgctgct
    24001 cgtcatggta agttattagg agtaaaagaa ttatttttac agaaactaat agatgaagtt
    24061 ataaaagtaa atgataaagc atatccagtt ttagttgaaa aagaaagtta tattaaaaaa
    24121 gtagttggaa tagaagaaga aaaattcaat gaaactatag accaaggaac agaaatattg
    24181 aactcttata tagaagtatt aaaaaatgaa ggaaagactg tcctaagtgg tcaagaagct
    24241 tttaaactat atgatactta tggcttccct atagacttaa ctaaagaaat attagaagaa
    24301 gaacatctat ctgtagatga agaagctttt aatgaagaaa tggaaaagca aaaagaaaga
    24361 gctagaaatg ctagaggaaa tatggatgga gaaagttgga aggaagaccc tctatcaaaa
    24421 ttagaatcta cagttgacag tacatttaat gggtatagtg aaatttatgg tgaaggaact
    24481 attgaagcta tagttaaaga tgatgagcta gttcaaagtg cagaagaagg cgataaggta
    24541 tctatagtac tagataacac tactttctat cctgaaggtg gaggacaagt tggagattgt
    24601 ggattgataa ctaatgaaaa cttagtttta gaagtattaa atactaaaaa aggtgctaat
    24661 aatagtataa aacatatagg tataataaaa tcaggaagaa taagtaatgg ggacaaagta
    24721 aagacactcg tagatagaga aactagaatg tcagctgcaa gaaatcacag tgctacacat
    24781 ttacttcata aggcattaag agaagtatta ggagaacatg ttaatcaagc tggttcttta
    24841 gtaactccag aaagacttag atttgatatt actcactttg aagcaatatc aaatgaagaa
    24901 ttaaaagtaa tagaagaaaa agtaaataat gttattttat catctttaga cataaaatgt
    24961 gatattatga atataaagga agctaaagaa aaaggagcta cagcactatt tggtgaaaaa
    25021 tatggtgatg aggtaagagt agtttctatg ggagattatt ctacagaact ttgtggagga
    25081 actcacttga caaatacttc tcaagtagga atgttcaaaa tattatctga aggtggagta
    25141 gcagcaggtg taagaagaat agaagcaata acaggaaaag ctgtttatga atacctaaaa
    25201 gaaagagatg gaattatctc tgaagtttgt gtaaacttaa aatctaaaga agataattta
    25261 attcaaagaa taagttcttt attagaagaa aataaaaact tatctaaaga attgcatgat
    25321 atgaaagcta agatgagttt acaatcagtt gattctattt ttgattctaa agttgaagta
    25381 aatggagtta atttgataac taataaattt gaaggtatgg atatggatac actaagagaa
    25441 acagcagata atctaagaga taagcttggt tctggtgtag tagtacttgc aaatgtagta
    25501 gatgataaag ttaactttgt agttactgcc actaaagatg tattagataa gggaatacat
    25561 tcaggtaata ttgttagaga agttgcaaaa atagctggag gaaaaggtgg aggaagacct
    25621 aatatggcac aagcaggagc tagtgatgta tctaaggttg accaagcttt aagctatgca
    25681 agtgaggtta ttaagacaca agttaaataa cattcactca aggaggtttt tagtttggaa
    25741 aaagatttag actacactat gaaatttgaa ggaataccag aagataggat gagtgtagga
    25801 gatactattg attttgtata taaagcatta gttgaaaaag gatataaccc tataaatcaa
    25861 attatagggt atctcctttc tggtgattct agctatataa ctagtcataa aaatgcaaga
    25921 gctataatta aaaaatttga aagagatgag atacttgaag aagtaatcac gcactatctg
    25981 aatagaaagt aggtcaaata aatgagaaaa aagattatgt cgttgtttgc aatagtcatt
    26041 atgatttttg tatcaactgc tagctatggt tttgctgaag aaaaaggcaa ggtcatattt
    26101 attgatatga ataggaccaa tcttggaagt atgatgaata ttccaatctt gaaaaatgag
    26161 atagaaaaga gaggctatgt agctctcatg aatataagag gggatcaagg tactgatgat
    26221 agaaggtctt atgcaagtat gggtgcagga acaagagcta gtgtaactac tgaagactat
    26281 atcaattttc aaaaagtaga ccaagatact gctaaagctt ttgaagtcgc aacaggtcaa
    26341 aaagctaaag aaataaatga tttaggcatt aatagatcta taaatgaaaa tcttgagtat
    26401 ggagaatatg gagcaaattt agggtcatta ggaaaaactt tatcagaaaa tggtttaaag
    26461 acatctgtaa ttggaaatgc tgatataatt gaaaataatc aattagttaa aaacagaaac
    26521 ttatgtttag tagctatgga ccaatatgga aggattgatt caggtaatat tgataatatt
    26581 aataagaaag attctaaaat gccatttgga atatctacag attatgataa attactagat
    26641 gaaactaaaa aatcctataa aaatagtgat gctatatttg tagaacttgg agatacatat
    26701 agattagata tgtatagatt aaatctaaat gataatactt atgatacaat gaagaaaaat
    26761 attgtaaaaa atataaataa atatcttgaa caagtatttt ctatggttgg agaaaatgac
    26821 actgtttata tagcaagtgc atttccaagt gacctagatt ataagaataa gagaagactt
    26881 tctccaataa taaaatttag tggagaaggg aaaggtctac tggaatctgc cacaacaaga
    26941 aaggctggaa ttgttgccaa tttagatgtt ggagtagata tactaggtac atttggtctt
    27001 gaaaataaag agatggtagg tagaagttat actttagtaa ataaagagga caatattagc
    27061 tatctaaaat cactttatga aaggatagtg tctatatctt caataaggtc aactattata
    27121 aatggctttg taggtgtaat atctgcttct tgggtaattg ccatgtttgc gattttcttt
    27181 agaaattata tgccacataa ggagcgtgta ttcaaagtac ttaaggagtt tataaaatta
    27241 ggcataataa tgccactatc atttatgtta gctcctttga tgaattttaa aactccaatt
    27301 tcaatatctt tgggaatatt tgcaactacg ctaatattat acttgttagg tagaaaatta
    27361 tttaaggaca atgatataaa gcacatggga ttttttgcaa cacttactat tttagtcata
    27421 gttatagatt ctgtatttgg aacatactta atgcaaaata acataatgag ttatgatgct
    27481 gtcataggag ctaggtacta tggtgtagga aatgaatatg aaggtgtaac tatagcaagt
    27541 gcagtatttg gcttagcagt attattacat tataagaagg tatctaaatt acttgttgta
    27601 attttttcat taataatact tataactagt gcatatcctt caatgggtgc aaatgttggt
    27661 ggagctatat cagaatgtgt agcatatttg ttgtttataa tgcttatata tgacattaaa
    27721 atagatttta agaaagctgt attattagct gtttcagctg tagttgtcgt ttttgcattt
    27781 gcagctttag atatactttc aggtagtgaa tctcatttag gtatgtttgt acagagaatt
    27841 ttcctaaatg gaccaggaga gatattacaa acatttggaa gaaaaattca aatgaatatg
    27901 caactagcac agacaagtgt atgggtaaat attttacttg taggaattgg agtaattgca
    27961 gtgcttatat ttaaaccatc tagacacttt agaaagataa tgaataattt tccaatcttg
    28021 tttaaagggt ttattgcatc tatggttggt tgtataatta cacttttagt taatgattct
    28081 ggaatagttg ctgcatctac agcatctata tatatactta taccactaat aataataagt
    28141 ataaatatga taatatttga aaaaaataac taaaaaaatt tttactgttc atataggatt
    28201 taaataaaaa atgcaatatg attattaatg taaactggat gcttacataa aaaatcatat
    28261 tgcaattttt atgattgatt atgtaaaatt atatgaagca gtaagcctgt gatcttagtt
    28321 atgagaggtt cagaatatgt atttaatcta tagaatataa atagataaag gaggaactat
    28381 gttagatgga agaataatgg gtcttgatgt tggtgataaa actattggag ttgctgtgag
    28441 tgatttgatg ggattaactg cacaaggtgt aaaaacaata aaaagagttg gcaagaaaaa
    28501 agatattgaa gagctaaaag caataataaa agaaaaacaa gtaaataaaa ttgtatcagg
    28561 attaccaaaa aatatgaatg gaactttagg tccacaagga gaaaaagtaa tcaagttttg
    28621 tgaattggta aaagcagaaa caggtattga tgtagagttt tgggatgaga ggctttctac
    28681 agtagcggca gagaggtctt tattagaagc agatgttagt agacaaaaaa gaaaaaaggt
    28741 tatagatatg ttggcagcag taataatttt gcaaggatat ttagatttta aaataaattc
    28801 ataaaagaac tataaaattg aatacttatg atatataata taaataataa aaataaaaat
    28861 aaatttgagg tgaatgacat tatggaagaa aatataataa atttaataga cgaaaatggc
    28921 gttgaaagcc aatttgaaat aatattaaca ttagaagcag aaggaaaaga gtatgcaata
    28981 ttaatgcctt tagatgatga agaagctgaa gaagctttaa tctttagaat tgatgaggat
    29041 gaagaaggtg aaatcttaat acctttggaa agtgatgaag agtatgaaac tgttgtagct
    29101 gtgtatactg ctataatgga agaagaaggt ttaaattacg acgaagatga atcaaatgga
    29161 cttaactaga taagtaatta agtttgtata taaaaatcag atatttatta tatttgcttt
    29221 aattaaacct tattaattgt aaaagcattt atagtatata tctgtttttt tgttttttat
    29281 taaaaatacc aaaaaattta tgaattttgg tgaataatat atcttttatg ggtatatatt
    29341 tatattatga gaataaatta aatttattta aatgtcttga caaaaaatga attatcaatt
    29401 acaatattat ttaataaaga ttatcaattg aaaatagtaa gggtgatgtt atggcaaata
    29461 caatggattt attaaaagac aagttaaaag aaactggttt taagattacg ccacaaagaa
    29521 gagcaatagt tgaaatattg cttaaacatg accattcaca tctaagtagt gaggaaatct
    29581 atgatttagt tagggttgac tgtcctgaaa taggcttagc tactgtatat agaacaatgc
    29641 agctattgga tgaaatagga ttaatatcaa aactaaactt agacgatgga tgtataagat
    29701 atgagattag tctacataaa gaagactgtc ataatcatca tcatcttatt tgtaaaaatt
    29761 gtggaaagat aatggaagct aaagaagacc ttttagacaa tatagaaaaa gagatacaat
    29821 cattgtacaa atttaaaata cttgatcatg atgttaaatt ttatggacta tgtgacgagt
    29881 gtaatggagt aagcgattca gaagaataaa cttctattgc ttaatgtcga tggaagaata
    29941 gtatagaact tttatattct atgctattct tccatttttt attataaacc atctataaaa
    30001 tgcaaatata cagttttcaa gatgcttata gttttaatat tgaaaatata attaatccta
    30061 taagtacaaa aatgaatgat ttttctatga aattactaaa tggtcctcca acagttaaaa
    30121 aacctaaaga aattttcttt tcgcttagcg gataaaaaat tggtattcct tgctttgtaa
    30181 ataaatctcc taaaaacata tgacttgcat aaccaatcgt accataaaaa gataaattat
    30241 taatattagt gattaattct atctgtttta gtaaaaaata tactattata gttgcaaata
    30301 tgctatgaga aaaacttctg tgctttaacc agggaaaaat tgacaacatt agacaaaaaa
    30361 ttgtaaaata tatttcaact tctatgatgt ataagcatat agctaatagt ataaatatta
    30421 atgatagaaa aacttttctt agaaatgtgt gggttagttt tgcttcaata attataattg
    30481 caacaaatgt aattattgcg cttaaataaa aattatcatt tatatttatt gaaataaaga
    30541 aaataataat attaacagca tatataaaaa ttctatatat gtatttggat acattgtttt
    30601 ttagaatgaa atttgagacc atagaattag atttatccaa atcgggtagt acagcaaaag
    30661 tagctgaaac taaaatatca actaaagata taggaatttt aaatattaaa gatgtttgga
    30721 tagctgttaa gattcctatt gcacaatgag ttttaccacg cataaatcct cctaaattat
    30781 ccgatattaa atcatataat atttagagga tatcaaaata aaataggttt gtcaaaataa
    30841 tacgttaaat gtattttaaa tatagcttaa aatatgatac gaattatggt acaataagaa
    30901 taactggtag cgagtgcgtg atttgatatt atttatgatt gtagaacgtg ttaaaaaatt
    30961 aaatagacag aaggagatga tgcaattgtt caaaaagaac accaacaaga taaaggtaat
    31021 ggccttgggt ggacttaacg aagttggaaa aaatatgact gttgttgagt ataaagatga
    31081 aataattgtt atagatgctg gacttagttt tccagaggat gaaatgttag gagtagatat
    31141 agttatacca gatataactt atttagtaaa aaatagggat aaaataaagg gtatatttat
    31201 tacacatgga catgaagacc atataggagc tcttccatat atattaaaga aaataaatgt
    31261 acctgtatat ggggcaagac ttagtatagg tcttatacaa gtaaaactta aagaacataa
    31321 aatgaataat gttaagttaa atgttatagg tcctagacaa gttataaagc ttgataatat
    31381 ggaagtagag tttttgaaaa ataaccatag tataccagat gcttactcta ttgcaataca
    31441 cacagaccaa ggtataatat accacacagg agattttaag attgacttga ctcctattga
    31501 tggagatgtt atggatatgc atagaatctg tgagttgagc aaaaaaggag ttcttttaat
    31561 gctggcagat agtactaatg cagaaaaacc aggatttact atgtctgaaa agactgttgg
    31621 ggtaggtctt gacgaattat ttgcaaaagg aaatggcaga agaattatag ttgctacctt
    31681 tgcatccaac atacacagat tacaacaaat aataaatact gctgaaaagt ttaatagaaa
    31741 agttgctata tcaggtcgct caatggtcaa tgtagttgga gttgcaaaag aattaggata
    31801 cctagatatt tctgatgaca tgcttataga tttaaatgat atatgtaagt atgaagatag
    31861 tgaattagtg ataataacaa ctggttcaca aggtgaacct atgtcagctc ttgctagaat
    31921 ggctttttca gagcacaaaa aagtagaaat aaagagtggc gatttagtta taatatctgc
    31981 tcatccaata ccaggaaatg aaaaattaat atcaagagta atcaatttct tatttgaaaa
    32041 aggagcagaa gtagtataca gtgatatagc tgatatacac gtttctggac atgcctgtca
    32101 agaagaatta aaacttatac atgcattagt tagaccaaag ttttttatgc cagctcatgg
    32161 tgaatataga atgttaaaaa gacatgctga aatagctgaa cagcttggta tggacaaaga
    32221 aaatattttt gtcatgcaaa caggagatgt tttagaatta gataaaaatt ctgctaaggt
    32281 agcaaaccgt atacaaacag gaaacatatt agttgatggt ctaggagtag gcgatgtagg
    32341 taatatagtt ttaagggata gaaagcattt atcagaagat ggtcttatga tagttgtagt
    32401 tactatttcc aaggatgagg gtaaggtctt agcaggtcca gatataattt ccagaggatt
    32461 cgtatatgta agagagtcag aagatttaat ggatggagca aaggatataa ttaagaatgt
    32521 tctaaatgaa tgtgaagaga aaaatattaa agaatgggct tatttaaaga ataatattaa
    32581 agaaaaccta aaagaatatt tatatcaaaa aactaaacga aatccaatga tacttcctat
    32641 cataatggaa gtataatata aaaaaactat aaatttgaaa attagacctc ttgtaatttt
    32701 taaagtaata tcaaaaatcc aattgatatt atcttaagaa ttacaagagg tctttttaat
    32761 actcatttta aaaaaaaata tattacataa aataccaatt ataacaatct tttattagta
    32821 aaaactactt atatataaat tttactgata ggaggattct tatggatgat gtttcaagac
    32881 aaaatgctat aaaagcttta aaacaaacaa aaatggaaat agcaggagag tatggaatga
    32941 attatgaaga tgcttttgaa ataatagaaa atgcgtctaa taaaggtgtt ttagaaggtt
    33001 actttaaaaa gcttgaaaag aaaaaaaatt taggtcaagg tatatctagg catttagaat
    33061 aaaaaaagtt aaatgtgaga aaataagttt aaataaactt taagaggtga catcgatgaa
    33121 aaaattagct agtactgctt tggctatatt aattgcgctt actcctttaa gcttttcttt
    33181 tgcaaataat aaggaaaatg ctgatgccaa ccaactaaat atatcttcaa aatcagcaat
    33241 tttgatggat gttggtagtg gacaaatttt atatgaaaag gatgctcata aaaagcttcc
    33301 tcctgctagt gtaactaagg taatgactat gctacttata gtagaagctt tggattcagg
    33361 caagattaag cttgatgatg aagttcaagt aagtgaaact gcatctagta tgggtggtag
    33421 tcaaatattc ctagagccag gagaaactca aaaggttgat acattattaa aaggtatagc
    33481 tgttgcttct gcaaatgatg cttgtgttgc tatggctgaa cacttagctg gaagtgttga
    33541 aggatttgtt gatagaatga atgctaaagc aaaagagtta aatatgaatg atactcattt
    33601 tgcaaataca aatggacttc cagttgcaaa ccactataca tctgctcatg atatagcttt
    33661 aatgtctaga gaactattaa aacacgaaat gataagtaaa tacttaacta catggatgga
    33721 taaggttgta gtagggaaga aacaagttac agtaggtctt gcaaatacta ataaacttat
    33781 aaagcattat caaggagcaa ctggtgttaa aactggtttt actcaagaag caaaatactg
    33841 tttatcagca tctgcaaaga gaggtaatac tcatctagtt gctgcaactt taggagcaga
    33901 gacttctcca gaaagattta atgatgcctc tagcctttta aactatggat ttgctaatta
    33961 tgaaagtgtt aagttatgta gtaaaggtga taatatagca acacttacat tggataaggc
    34021 tgatgaaaac aaagttaaat tggttgctaa agaagattta aatgctctta ttaaaaaagg
    34081 aagttctaaa gaatttgaga agaaaattga aatagtaaaa aatcctaaga tgccaattaa
    34141 aaagggaact gttttaggaa aaataaagat atgtaaagat aaaaaagtaa taggcgaagt
    34201 ggaattgata aatactaagg atataaataa ggcaagctat ttacaaatgc ttcaaagaat
    34261 aattgataat atgatataaa taattatcag atgaaatata attataatac acaaagatat
    34321 gattataata cacataaaaa atacccttat gtaattattt gccatagggg tatttttatt
    34381 taccatatag aagtatttta taatcttatg atttttatag aaatatagaa aagtttatgt
    34441 atcttaaaat atcatttgat ttaatatcat atatagggtt gtttaacaat tatctaagta
    34501 aaggcatact accagtaagt ttattcactt tctttttatt cccataaatt gctatcccaa
    34561 aatactgtaa ctcatcttct ggaacactag caatcttttg tgtaaattct tcataaagat
    34621 tgcaactttg tgctacatct gaaaaatcta caacagttaa atcgttaaat tccaaagtat
    34681 ataatttttt acgtaaatct tttattattt ctttgtttcc ttttaaaata ggtacaggaa
    34741 tgtcaataat tcctaagtgg ctattacctg ttttgtcaat tacatctggg ccaacagttt
    34801 ctggggcatg ttttcctagt gtaattccca ttatagctgc tgtattggat ataattccca
    34861 ttggtaaatt ttcgtctatt accatgacac attttgaatt tttagtttcc atttttattt
    34921 ctccttttta ccttatttaa agttgtttga atcatcattt ataaatatat tttgatactg
    34981 ctttggtgta agaccaataa aattcttaaa aaagtttgta aagtgacttt ggtctacaaa
    35041 tcctgtttgt atcgcagcat ctataggttc tacgcctttt tctaaaagct ttttagcttt
    35101 gtttacccgt atattttcta ggtatctata tggtgtaata ccttttaatt tcgtaaaatt
    35161 acgaagtaga gagtacttat tcatacctgc tatagtgctt aattcgtcaa gtactatatg
    35221 ttcagcataa ttattttcta gataatcaca tactgcttga atttctatat ttgtattttc
    35281 caagttagat tgcaaatttg gctctgtatg ttcttcaatt aattgttcaa ttaggaagaa
    35341 aaaaagctct tcctttttaa aatccaattc ttcttccatg attatatagt gtaattcttg
    35401 tagtagaggt actagctcac tgcgaaatat aacaggttga ttaaattttg gtaaataatt
    35461 tttacctgta atttcaaaga cagttttttt cattatttct ggcttaatat taatacatct
    35521 gtaatcaagt actttatcat ctatttgttc acaagtatga ctatcaaaag ggttaaaaag
    35581 tagcaaatct ccagtacttg tggtatactc tttattttta caagataaat atctttgacc
    35641 tttttctata aaaccaatta cataatgttc atgaaaatgg tttgggaatt tttgcattat
    35701 gcctttaaat ctatatgctt caatttttaa ttccctatca aagcatactg tgcgttcttc
    35761 ttgtctcact taggtaacct cctttcatgt tatacaaagt gtaacacata tttttttata
    35821 cttcttgtat aatattgact aagagacaat aatgtcaatt catgtcaata taatattata
    35881 cttacagtag gtgtaattat tatattttca caatgaatat gatataataa taaaagttat
    35941 aaaataaaaa gcaaatttta attttatgcc tagaagttaa aattattata atgtaaaata
    36001 attttgatta taagctattt aattgttata ataatattaa aaatttaatt taggagatgt
    36061 acattaatgt taagtatgaa tataggagaa atagtagcaa gtttagttgg tatagctatg
    36121 gcaatatcaa tacatgagtt tggccatgct tattcagctc acttattggg ggatgataca
    36181 gctaaagctt atggtagaat gacattaaat cctgtaagac atgttgaccc aataggtctt
    36241 ttggctatgt ttatccttaa gatagggtgg gcaaagccag taccagtaaa tccaaataac
    36301 tttaaaaact ataagatagg aaacctgata gtttcacttg caggcgtttt ttgtaatgtt
    36361 ttgactgcta tactgtgtgt aattatcaat aagtatgtgc atatgtatgc tataaataca
    36421 atagctggat atgtgctttt atatagtatg ggatttgcag cttttaactt acttccgata
    36481 cctccacttg atggatgggg agttatatct acatttgtac catataaatg gaatgaatat
    36541 ttgtataaat ttgaaagtat gagttatata attttattaa ttgctttatt tactggtatg
    36601 tatagaataa tactatcacc aatatataca gtgttgctaa aaatagtata tttatttgtt
    36661 taatataata aacagattaa agagggattg atatgaagta taatatacaa ttacaagtct
    36721 atgagggacc attagattta ctttatgatt taataacaaa gcataaaata gatataaagg
    36781 atatatctat aatagatata actaagcagt atctaaatta tttgaaaatg ctagataaaa
    36841 tggatttaga gataactagt gaatttataa ctatggcatc aaaactttta gagataaagt
    36901 ctaaatatct gctttataag caaaaagatg aagaagaaga cccaagaata gaacttatgg
    36961 aaaagttaga agaatataga aagtttaagg tagcatcaca agatataaaa gaaaatataa
    37021 cttatgttaa tgagagattt tatagaaata aagaagagat aattattgat gacaatgtgg
    37081 atttagaaga tatatcaatt gaagcaataa aaaatatact tccatacata tttaaagtta
    37141 aaacatcaca gatagaaaat gctaatgatg agaaactaga taaaatagta aggaagaaaa
    37201 taatatctgt agaagaaaaa atattatata taagagatat tataaaagat aagattgaag
    37261 ttacttttac aaatattata aaatcatatg aaaatgatga aataatagct acttttttat
    37321 ctatattaga gcttataaaa gaaaaagaaa tagtcgtagt acaagatata ttttttgatg
    37381 atattctaat aagaaaaagt tcggagtgtt aaaatgaaaa gagaagatat aaagtatatt
    37441 atagaatctg ttatgtttgc atatggtgag ccaataagta taaaagaatt aaactatata
    37501 ataaataaag aactttcatc aaaagaaata gagattatgt taaatttact tattgaggag
    37561 tacagagaac aaaatagagg tattcaaata atcaagttag agaataagta ccaaatgtgt
    37621 acaaataaag actatgcaga atatataaag aagattattg aaccaaagaa aaagaaaagt
    37681 ttgagccaag ctacattaga aactcttact ataattgcct acaaacaacc aataacaaag
    37741 gtagaaatag aggatataag aggagtaaaa tgtgataagg tattacaaac tttgtttgaa
    37801 aatgaactta taagagaagc tggtagattg aataagatag ggaaaccaat aatttataaa
    37861 acaacagatg aatttttaaa gttgttgaat atagaaagtc ttgaagaatt gccacctata
    37921 gaaaattatc aagaagtggc aacaaatgaa taaaaatata aaatcacaat aatttagtat
    37981 gtaattttaa attttaaaag atttaaaatg ctctaagttg ttgtgttttt ttgtataaat
    38041 ataaaattat aattctctta aaataaatat ggataattaa gtataaatag taattttttg
    38101 atgataatat aaacatggag cttaatgaat tatttaattt taagtattta ataatagctg
    38161 taatttttat tataagtgta actatgttga ttttaatatc tcatataaac atcttaataa
    38221 tagctgatat aaaaaacaaa gatatttgtt taaagcttaa tataaaatac atgtttaatt
    38281 taataaatat aaatagacaa ctttatccag ctgaaaatag taaaaataat gataaaaaag
    38341 aggggatgaa gaataatata gattcaagta tattattagc tgatgacctt ttgagcattt
    38401 atagattatt aaaaaagata aaaatacatg aactttattc aaatattaat tttggaactg
    38461 gaaatattgg cttaacatct tctgtatatg tattgataaa tactttgtat ggaaatttat
    38521 ttaatatgat tgatgcagaa aaaatgtatt taaatgtaaa tccagatttt acaaaagatt
    38581 atgttttagg aaatataagg atacatataa ggccaagaat aaaagcttta tttaatatta
    38641 taataatgat taataaaatt atgaataaaa ataaaggaaa taaggaaggt gatagtaatg
    38701 agagcaacag gttcgataca gagtcttatg gaaacaactc ttgaaacaat taaaggttct
    38761 atagatgcaa atactattat aggagaccct ataaaaacag atactacagt ggttgtacct
    38821 atatcaaagg ttacaattgg ctttggtata ggaggaggag aatactcaaa aggatatgat
    38881 gataaagata gggaaattga attaaaaaat gaaaaatcag atacgaattt tgctggaggt
    38941 agcgcagggg ctatatctgt acaaccagta gcatttgtag tagttgaaag tggagagact
    39001 agaataatga gtttagatag taatatcaat ctagtggata atatattatc tataactcct
    39061 agagtattgg agaaaattca aaatatatca caaagtaata agaatcaaga taaaaacaat
    39121 atgtaagaat aaaatatttt taaatatgta tatagtttta agtaaagtag tggggttaat
    39181 ataaatccca ctattttgtt gtgtacttta aacatttata tctaataaga ttttagttta
    39241 aaacaattta aatagataat aaagttgata tatagtataa ttataaaaag aaaagaagta
    39301 ttatattata gatatataaa cgcatttgag atataagagg gagttataaa tcattagttt
    39361 tgaggtgaat gttatgagcg ataaagaatt atctattttg ttgttagaaa gtatgaataa
    39421 ttttcataat ttaataaaga ttattaataa cgaaagatat aaaaaagata aggttcttac
    39481 agaaagacag ttctttgcct tagtaaaaat aagaaaacat gataaaatag agcttaaaaa
    39541 tctaagtaga gatttgcatg tatctacttc tagtctgtgt atactactta ataaattggt
    39601 tgagcaagag tatgtatata gggaagaaga tagtagagat agacgaaata ctttttatgg
    39661 aataactaaa aatggagaaa agatattgga taatgaaata ctaaagtttg tatctataat
    39721 aagtgataaa atggattgcc tagatataga taataaagat aaattattta cttctttgga
    39781 agagtctaaa aatataatag aacaattatt ttaaaaagga gaatttatta tgaatataaa
    39841 gtattctaaa gagatattaa aaagtttaga aaatgctata acagtagtag ctctatttga
    39901 gggagaagat gtttttacga catttgataa aataaatatg ataagcagaa attttaattc
    39961 taaagaaaat agtatagata ctgtaacatt aattgaaaat aacaatttgg taaatgtttg
    40021 ttttgttggt tttggtaaga gagagttatt gaatagagaa aaaattagaa tcataggtgg
    40081 gaatttgtgt aaaaaattaa aaaatatatt gaaaaatgaa gcatataaga gtagtgatgt
    40141 taatgtactg aatcttaatt taaatagtga tgaaataggt tgttttgtag aagggatatt
    40201 acttggaaat tataagtttg ataagtataa gacaaaaagt aaggattttg aaagaaaaga
    40261 agttgatact ataactatat ttactgaaaa agaagttgag tgtcaaatag aaaaggctaa
    40321 aatattagct aattcaacta taatagctag aaatctagtt aatgaaccat caaacgtaat
    40381 atatccaaaa acattagcag tagaaacagt taaacttggt gcagagtttg ggtttaatgt
    40441 tgatgtttat gaagaagaaa aaataaaggc attgggaatg gatgcttttt tcgctgtttc
    40501 aagaggttca attaataaac caagattcat agtaatgaga tactttggag ataaagaaag
    40561 tacagatata ttaggtctag taggtaaagg attgacttat gatactggtg gatattcttt
    40621 aaaatcaaat gcttctatgc tagatatgaa gacagatatg gctggtgctg cgagtgttat
    40681 aggtgctatg tgtgctatat ctcaaagtaa attaaagaaa aatgttatag cagtagtggc
    40741 tgcatgtgag aatgctttat caggaggttc atacaaacct ggagatataa ttagttctat
    40801 ggcaaagaaa actattgaag ttttaaatac ggatgcagaa ggtagactta cattagctga
    40861 tgcaatatac tacattataa acaatgaaaa agtaacaaag gtggttgatg tagctacatt
    40921 aactggtgct gctttaacat tgttaggtaa tgttgcaact cctatagtaa caaataatga
    40981 tgatttttat tgtgaattag aaaaagctgc cactttatca ggggaaaggg tatggaagat
    41041 gccaatttat gatgaattta aagatatgat aaaaggagaa gaagcagacc ttaaaaacac
    41101 tggtggtaaa aatgctggat gtataacagc aggagctttt attggtgaat ttgttgggaa
    41161 tactccttgg atacatatgg atatagcggg gacaagtaca tcatcaaaat caattggata
    41221 caaagcaaag ggggctacag gagaacctgt tagaacattg tactatttgg cagaaatcta
    41281 aaaaacaatt ataaaatata atttataaag ccacgtggat atttttgtaa tttaagatta
    41341 tctatgtggc tttatttttt atttaagtaa attatttact ctttttcttt ttttcaagta
    41401 taaaagtatc tctattaaat aaaagagcag gtatgtacat aatactagta acaaaaataa
    41461 acgtaaaaat agcagttgtg ctatgactta aaaaaccata atagtaccta gagttggtaa
    41521 atgtgtttag taaaaatatg aatgaaaaat aaataaaaca tatagctaag ttatctctaa
    41581 gtgcatatct gttaactcta aattttctaa catcaaccat atatatatct gcataaatta
    41641 tcaagcactt agagaagata aagataaaat atattaagct aggaaattca tagcccaagt
    41701 ttttagaaaa aatgagttct ccaactgaac aaactaaact ccaagaaaaa aatatattaa
    41761 aaagatgata ctgcttaaaa attagtatgg ctatacacag atatatacaa atataattga
    41821 ttccaattgg taaagagttt agagtactat aattacctga agaaataagt aataattgct
    41881 ctagagccat aattattaca agtaatgtac aaattatctt ctcaactgta tagctataag
    41941 gtaaaatatt tttggttagt tttggacaat agtataaaaa taatccaaat ataaagagac
    42001 ttacaaattg ttcactag
//
LOCUS       DAEQAF010000027        41514 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.028, whole genome shotgun sequence.
ACCESSION   DAEQAF010000027 DAEQAF010000000
VERSION     DAEQAF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41514
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.028"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            190..1620
                     /locus_tag="KRN00_001510"
     CDS             190..1620
                     /locus_tag="KRN00_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1827377.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
     gene            1988..2566
                     /locus_tag="KRN00_001511"
     CDS             1988..2566
                     /locus_tag="KRN00_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH1827378.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            2596..2742
                     /locus_tag="KRN00_001512"
     CDS             2596..2742
                     /locus_tag="KRN00_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH1827379.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            3047..4426
                     /gene="scfB"
                     /locus_tag="KRN00_001513"
     CDS             3047..4426
                     /gene="scfB"
                     /locus_tag="KRN00_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBH1827380.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            4455..4952
                     /locus_tag="KRN00_001514"
     CDS             4455..4952
                     /locus_tag="KRN00_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBH1827381.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            5250..6914
                     /locus_tag="KRN00_001515"
     CDS             5250..6914
                     /locus_tag="KRN00_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBH1827382.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            6927..9377
                     /gene="recJ"
                     /locus_tag="KRN00_001516"
     CDS             6927..9377
                     /gene="recJ"
                     /locus_tag="KRN00_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBH1827383.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     SIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDISLIDLDFNINYNIIEDVSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            9390..9902
                     /locus_tag="KRN00_001517"
     CDS             9390..9902
                     /locus_tag="KRN00_001517"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBH1827384.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            9976..12183
                     /locus_tag="KRN00_001518"
     CDS             9976..12183
                     /locus_tag="KRN00_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBH1827385.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            12208..12657
                     /locus_tag="KRN00_001519"
     CDS             12208..12657
                     /locus_tag="KRN00_001519"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBH1827386.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            12672..13286
                     /locus_tag="KRN00_001520"
     CDS             12672..13286
                     /locus_tag="KRN00_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1827387.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            13377..14933
                     /locus_tag="KRN00_001521"
     CDS             13377..14933
                     /locus_tag="KRN00_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBH1827388.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNANNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            14923..16185
                     /locus_tag="KRN00_001522"
     CDS             14923..16185
                     /locus_tag="KRN00_001522"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBH1827389.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEEANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            16259..18046
                     /gene="aspS"
                     /locus_tag="KRN00_001523"
     CDS             16259..18046
                     /gene="aspS"
                     /locus_tag="KRN00_001523"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBH1827390.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETPPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            18505..19737
                     /locus_tag="KRN00_001524"
     CDS             18505..19737
                     /locus_tag="KRN00_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH1827391.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSIVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMKCFGIKDK"
     gene            19751..20557
                     /locus_tag="KRN00_001525"
     CDS             19751..20557
                     /locus_tag="KRN00_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBH1827392.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYNADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(20669..21538)
                     /locus_tag="KRN00_001526"
     CDS             complement(20669..21538)
                     /locus_tag="KRN00_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1827393.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            21910..23337
                     /locus_tag="KRN00_001527"
     CDS             21910..23337
                     /locus_tag="KRN00_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBH1827394.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGIKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETVEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            complement(23414..23683)
                     /locus_tag="KRN00_001528"
     CDS             complement(23414..23683)
                     /locus_tag="KRN00_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827395.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMKGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(23686..25128)
                     /gene="nhaC"
                     /locus_tag="KRN00_001529"
     CDS             complement(23686..25128)
                     /gene="nhaC"
                     /locus_tag="KRN00_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH1827396.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            complement(25153..26319)
                     /locus_tag="KRN00_001530"
     CDS             complement(25153..26319)
                     /locus_tag="KRN00_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1827397.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVILPDEKYYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            complement(26544..28664)
                     /locus_tag="KRN00_001531"
     CDS             complement(26544..28664)
                     /locus_tag="KRN00_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827398.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKKSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            28897..29298
                     /locus_tag="KRN00_001532"
     CDS             28897..29298
                     /locus_tag="KRN00_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827399.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            29341..29634
                     /locus_tag="KRN00_001533"
     CDS             29341..29634
                     /locus_tag="KRN00_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBH1827400.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            29649..30089
                     /locus_tag="KRN00_001534"
     CDS             29649..30089
                     /locus_tag="KRN00_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBH1827401.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(30181..30654)
                     /locus_tag="KRN00_001535"
     CDS             complement(30181..30654)
                     /locus_tag="KRN00_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1827402.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(30654..31442)
                     /locus_tag="KRN00_001536"
     CDS             complement(30654..31442)
                     /locus_tag="KRN00_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1827403.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            31770..33014
                     /locus_tag="KRN00_001537"
     CDS             31770..33014
                     /locus_tag="KRN00_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH1827404.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            33337..34434
                     /locus_tag="KRN00_001538"
     CDS             33337..34434
                     /locus_tag="KRN00_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBH1827405.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            34425..35123
                     /locus_tag="KRN00_001539"
     CDS             34425..35123
                     /locus_tag="KRN00_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1827406.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYSYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            35126..36190
                     /locus_tag="KRN00_001540"
     CDS             35126..36190
                     /locus_tag="KRN00_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1827407.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            36373..37077
                     /locus_tag="KRN00_001541"
     CDS             36373..37077
                     /locus_tag="KRN00_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827408.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDSQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            37070..38392
                     /locus_tag="KRN00_001542"
     CDS             37070..38392
                     /locus_tag="KRN00_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1827409.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            38558..39931
                     /locus_tag="KRN00_001543"
     CDS             38558..39931
                     /locus_tag="KRN00_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827410.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFER
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTSVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(40303..41241)
                     /gene="pdaA"
                     /locus_tag="KRN00_001544"
     CDS             complement(40303..41241)
                     /gene="pdaA"
                     /locus_tag="KRN00_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBH1827411.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
BASE COUNT        16012 a         4716 c         7058 g        13728 t
ORIGIN      
        1 tactaatggg atggaaaatg tccactatta actttattac cccacatata taagataaaa
       61 ttattaatat aaaatataat ctatcgacaa tgaatagact tttaaataaa cttaatataa
      121 aattaattaa ataagtgctt aaaaacgatt tactttaatg atagaatcat attaaaggag
      181 gataatttta tggatataaa gaataaaatt aaatctatat ttttaccaga aaaaaatgac
      241 tatttagatg atgaagaatt tgagtatgat atagaaaata atgaagaaga tttaaaggaa
      301 gataacaaag tacatttaaa tgatttaagc agagtaaaat atgattacag agagttaaaa
      361 gacatagaaa accaaacaga agagatgtgt ctgctagcag taaagcagga tggtactata
      421 attgagtttg taaaggacaa gacttataaa gtatgtatgg aagcagtaaa acagacatat
      481 aaatctctta agtatataac aaatcaaaat gaggatattt gtatagaagc agtaaaacag
      541 aactacagag ctttgtacta cataaataat aagacagaaa atgtactaat tgaggctata
      601 aaaaatgcat caacttatga tgtcatggaa gtatttaaat ttgtggaaga gcaaacagaa
      661 gatgtatgtc tagcatttat agaaagggca tctaaaaatg atgttgcaga gatattaaaa
      721 ggaataaaag agcaaactcc agccatatgt ttagaagctg taaaaaaaga tggaaaatct
      781 ttagcttatg taaaggaaca aagtaatagt atatgtttag aagctgtaaa agaaaactac
      841 agtgcactat cttgtgtaaa agagcaaact gaagaaatat gtatagaagc agtaaaacag
      901 aatgactttg cattgtatta tgtaaatgaa cagacagaaa aaatatgcat ggaagcagta
      961 aaaagaagtt atatggctct acagtatgta aataagcaaa cagaagagat ttgtttggaa
     1021 gcagtaagaa ttgatggaag agcattacag tacgtaaaag agcaaacaga agaaatttgc
     1081 ttggagtcag ttagacaaaa tggaaaagta ctgcaatatg taaaaaaaca gactgaaaat
     1141 atatgtatag aagcagtaag aggttcattt gaagaacttg aaataaaaga aatattaagt
     1201 tatgtaaaga taccaacaga aagaatattt gtagaagcag taaagcaaaa tggaaaaatt
     1261 cttaaatatg tagaaaatca gacagaatta atatgtttag aggcagtaag agaaaactat
     1321 aatgctttag cttatgtaaa ggaacaaaca gaaaagattt gtttagaagc agttaatcaa
     1381 agttatgaag cgcttaaata tgtgaaagaa caaacagaag aagtttgtct aaaagcagta
     1441 aaacaagatt atagaatgtt gaaatatgta aataatcaaa cagaaaaaat atgtttagaa
     1501 gcagtaaagc aaaattatag agctttagaa tttgttgata atcaaacaga aaaagtttgt
     1561 cttgaagcag taaaacagaa tagaaaagca ctacagtatg taaaacaaaa acaaagttaa
     1621 aaggctaaaa tatatagaaa acatatgcaa ataaataaaa tttgatattt tgtaataaat
     1681 aaaatgggta tctcaaaagg aactttttag tttgtgaggt actcttttta tatgaaatga
     1741 aatatatttt tagcctttta acaatgggga aaaggtttat ttctattttg acataggctt
     1801 tttatgcata taaagcttga taaaattgtt ttattataat tgttttgtta tataaataat
     1861 aagaagaaaa ttatataggt ctttttttga ccagttttac atttttaaca actagttttg
     1921 taaagtatat tgaattttct caaaaaagaa tgtactctat atatgtaaaa tttttttgga
     1981 ggtaaaaatg tttaaaagat atgctgaaaa aatgacatct gttttaattt gtaataatat
     2041 gatagataat aatgaatcta aagtctattc ttatggattt gaaatattaa tagctttcat
     2101 agttaatata accaccatgc tgtttatagg ttttttattt ggtaaattta catatgtatt
     2161 atttttttta atgtgttatt gtccaataag acaattttca ggagggtatc atgcagacaa
     2221 ttattttaga tgcttattaa cctttatttt tataatttta tctacaatct taattataga
     2281 aaatataaat atagacttat ttaaaaatat tattatgatt attgcaagtg ttagttgggt
     2341 tggaatttgt gttctgtgcc caatagaaca taggagtaac cctataagtg atagggaaaa
     2401 attggtttat aagaaaactg ctatatttat atctacagta gtgttattga taacaatttt
     2461 aagtctttct ttgagtatat ttgtagatta tttcacatat agcgcatttg ccatgttttg
     2521 gatttttgtg atgttagtat taggtaagtt aaaagctaaa gtataagtaa aatatgtatg
     2581 agggagagtt aagttatgaa aaagtttatt gtaagattta tgaagtttgc tagctcattg
     2641 gcacttagca ctgctatttt gtcagctaat agtacctgtc cttggattat tcatcagcct
     2701 aaagtaccca aagaaatcag caatctaaag aagacaaatt aaatacaagc acttatttat
     2761 acaaaattat caggaaaaaa gaaattatta tattttaata agattaaaac aatataaaat
     2821 cagatacaaa atttatttta tttattttat aggagcctaa tacctatttg gtaatatatt
     2881 agtgcgccaa tttaggggga tatagtgtat ttaatgaaat gacttacgga gagtaagtca
     2941 tttttgtatt gtatgtattt tatgtaaact tatgatataa tgaagggtaa agtttaatta
     3001 aaataataaa aaactttagt atagatagta atttaggagg tagggtatga gtatgataca
     3061 taaattttct atgaatggat ataatatcgt tttagatgtg aatggtggag ctgttcatgt
     3121 gttagatgat gttgcatacg atttgttaga tttttataaa gaaaaaagta aagaagaaat
     3181 attagagata ttaaaatcaa aatatcaaga agaaaaaata aatgaagcat atgaagaaat
     3241 attaaatttg gaaaaagagg gtcttttata tacagaagat acatatcaat atcatccaag
     3301 ctttgtacat agagagcctg tagtaaaagc tttatgttta aatgtagctc atgattgtaa
     3361 cttaaaatgt aaatactgtt ttgcagctca aggtgatttt ggaggagaaa aagaacttat
     3421 gagttttgaa gttggtaagg cagcaattga ctatttgatt gctaattcag gaagtagaaa
     3481 gaacctagag atagatttct ttggtggaga gcctttgatg aactttgaag ttgtaaaaca
     3541 actggttgac tatggaagaa gtgtagaaaa agattataat aaaaatataa gatttacaat
     3601 aactacaaat ggtgtactgc taaatgatga gattatagat tatataaatg aaaatatgca
     3661 taatgtagtt ttaagtttag atggaagaaa agaagttaat gataatatga gaccaacttt
     3721 aaatgataaa ggaagttatg atattacatt accacgattt aagaaacttg tggaaaaaag
     3781 agcaaaagat aagtattatt atataagagg tacttttaca agagataatt tagatttttc
     3841 aaaagatgtt atgcattttg cagatttagg atttaaatta acctctgtag agccagttgt
     3901 tggagatgag agtaatccat atgcacttag agaagaagat ttacctaaga tatttgaaga
     3961 gtacgaaaaa tttgctgtag agtatgcaga tagacaatta caaggagatg gatttaaatt
     4021 tttccatttt atgatagacc taaatcaagg tccatgtgta ataaagagaa taactggatg
     4081 tggagctgga aatgagtatc tttctgtaac tccaaatgga gatatctatc catgtcatca
     4141 atttgttgga aatgaagaat ttaaaatggc aaatatattt gatgaagaaa tagtacttcc
     4201 agaaaattta aaaaatatgt ttagagaagc tcatgtatat actaaagaag agtgtaaaca
     4261 atgttggaat aagttttact gttcaggtgg atgtcatgca aatgcgataa actttaataa
     4321 tgacatatca aaaccatatg aattaggatg tgaaatgcaa agaaaacgta cagagtgctc
     4381 tataatgata caagctaagt taatgttaga aggagcaacc aactaaattt atattttaaa
     4441 ggagttgttt atatatgatt agagattatt tagaagataa acctttaatt gacgaaagtg
     4501 tatttgtggc aaaatcagca gatgtaattg gaaatgttaa aataggcaaa gattcaagta
     4561 tatggtacaa tgcagtagtt aggggtgatg aaggaccaat aactattgga gaaaacacta
     4621 atatacaaga ttgttctata gtgcatggag atacagaaac tataattggt aacaatgtaa
     4681 cagttgggca taggtctata gttcatggtt gtaaaattag tgataatgtg ttaattggta
     4741 tgggttcaat aatattggat aatgctgaaa taggagaata tactctgata ggagcaggta
     4801 cactaattac atctaataag aagtttccac caggtgtttt gataatgggt tctcctggta
     4861 aggttgttag agagcttaca gaagaagata aaaaatatat tgatgaatct tatgaatggt
     4921 atttagaggc agcacaaaat caaaaatatt agtttaaaga gtggttgttt caaaacatat
     4981 ttaaatctgt tttgaggcaa ccactaattt attttattag attttgttga tattttagtt
     5041 ttcaaaaagt atttgattaa accagatata aaatgtcaaa aataaaaatt aactgagtta
     5101 aataatttta ataaaattgg tagtatatgt gataaaatta aatattaaag aggatatagg
     5161 atattagaat atcaattggt gaaataatgt catatacgat aaattaaggt gtaagttttt
     5221 gggtatacct atcttaggag tgaaaagatt tgagaataag ttatagaaat ttaaagcgat
     5281 atagagaaat tggatatgtt ttaataaagt atggttttag ttttattgta gaaagactaa
     5341 atatagaagg aattgcctat aaaataccac tatttgaccc accagaagaa ataaaaaata
     5401 tgacaactgg tgagagaatg aaaagagttt tagaagaact aggacctaca tatataaaaa
     5461 taggacagat attgagtaca agaaaagact tgttagacca ggatataatt gatgaaatat
     5521 caaaactcag agatgatgta gagaaatttg attcaaatat agctattgat atatttaaag
     5581 aagaagtggg tttaagtata gaagaaatat tcttagaatt taaagaagaa ccaatagcag
     5641 cagcttcaat tggtcaagtt tatgaaggtg tacttaaaac gggagaagaa gtaatcgtaa
     5701 aaattcaaag accaaatata gagaaaataa taaaatctga tttagagatt cttagaacta
     5761 ttgcaaatac tttaaaagat ttaaaaaaag attttaattt agatttagta cagatgattg
     5821 aagaatttca aactcaatta atgagggaac ttgattatac atttgaagct ataaatgcaa
     5881 ctaaattctc taggatattt aaaaatagtg atgaagtata tatacctaaa gtatattcag
     5941 aatataatac taagaaaatt ttagtaatgg agaaagttaa tggtacaaag ttaagtgatg
     6001 tagaaaaaat aaggagacta ggttataaca caaaaactat tgttgaaata ggcgttagat
     6061 cattttttac acaggtatta tctcatggat tttttcatgc agacccacat ccaggtaata
     6121 tattcgtagt tgctaaaaat aagatagcat atatagattt tggaatgatt ggaattattg
     6181 ataataaaac tttaaaccaa ttaaatgaaa ttgcattagc aggtgtagaa aagaatgttg
     6241 acaagataat atatctattg atagaaatgg atgcattaaa tggagaggct gatattaagg
     6301 gacttagaca ggatttactt tatctaatac attattacta tgatatttct atagaaaaaa
     6361 taaatgtaac agatatatta aatgaactat ttaggttttt tagacagtat aaaatagtca
     6421 tgcctgcaca atttgtaact cttgcaaaga cagttataac attagaagga acaagtagaa
     6481 ctttaaacac agatttttct tttggttcta tgggaaaaga gtttatgaaa catcattata
     6541 agagtaaatt taaccccaaa aatgttgttt taagttcaag acaaaatgta gaagaaatat
     6601 tactggacat aaaaactatt ccaaagcaat taaaagcaat tttaaaaaat atagaaagaa
     6661 ataatataaa aatgcaaatt gaagatgtta aaatgacgag gttagaaaat tgtataatag
     6721 agctaacatc tcaaatatct ttgagtttag tgttggcatc tattatagta ggttcttctc
     6781 ttataattgc atctccaaat atagaaaata atatatggat aaaatttact gcaatagcgg
     6841 gtttctttat atcctttata ataggccttt gcttagttat aagaagtatt aggtcaaaat
     6901 acaaaaaaga ttagggggaa ttaaatttga aaaaatggat attaaagtat aaaggtaaga
     6961 tagaggaaag tgaatttagc aaaaaactta atatttcccc ggaaatctgc caaattttaa
     7021 aaaatagagg gatatgtact gaaaaagatt cagagatatt tatgaatcca tctttagatt
     7081 atttaagaga ccctttttta atgaaagata tgcaaaaagc tgttgataga ataaagttag
     7141 cagttgagaa gaacgaaaaa atttggattt acggagatta tgatgttgat ggtgtatcat
     7201 ctacatctat cttgtgctta tattttaaga gtataggtta caatgttgat tactatattc
     7261 ctaatagatt agaagaaggg tatggtataa atgaagatgc tattaagctt ataagctcta
     7321 ggggctgtga cttgattata agtgttgact gtggaattac atcagtgtct gaggtcaata
     7381 cagcgaatga tttgggcata gatgttataa ttacagacca tcatgaatgt caaagtgaaa
     7441 ttccatcagc ctttgcagta ataaatccaa aacaagaaga ttgtaattat ccatttgatt
     7501 cactatgtgg atgtggtgta gcatttaaaa tgattcaagc cttgactcca aaagaagaat
     7561 ttaaaactag tatgtataat tatttggaaa tagtaacact agcaactatt tgtgatattg
     7621 ttccacttat agatgaaaat agaataattg taaaaaatgg tttaaaatca atgaaagaag
     7681 gcaaaaatat tggattaagg gagcttataa aagtttgtgg tgtagaaagt gataagatag
     7741 gttcttctca tataggtttt gcaataggtc ctaggataaa tgcttcaggt cgattgggat
     7801 attcttactt aggagtagag ctatttacta ctcaatcaca agaagaggca gtagaaatag
     7861 ctagtatatt ggaagaaaaa aataatgaaa gacagatgat agaagctaag atgtatcatg
     7921 aagctgaaga aatgctaaag tctaatagca gatacaatga tgacaaggtg ttggttttag
     7981 ctaaagaggg ttggcaacat ggaataatag gaattgtagc atcaaagtta actgaaaaat
     8041 actacaaacc aacaattctt ctaggtatag aaaatgggga ggctactggt tcagcgaggt
     8101 caataaaagg atttaatata tttgaagctc tcataaagtg caaagacttg atgactaagt
     8161 ttggtggtca tgaacaagca gcagggttat ccttggattc agacaatgta gaaattttag
     8221 caaatgaaat aaataaattt gcagattata atttaactga agatgatatg atagagaatg
     8281 taaatgttga gtttgaatta caagaaaatg taataaattt aaatcttgta gaagaattac
     8341 ataagttaga accctttgga ttaaataatc ctaatcctag atttatagtt agaaattata
     8401 ttttaaaaga tttgaaagtt ataggtaaga atcaacaaca tctgaaatta agtatagaaa
     8461 aagagaaaag ctatgaatgt ataggattta atatgagtca tttaaaatca atgtataaag
     8521 taggagacaa agtagatgta ctattccaat tagatgaaaa taactatatg ggaaatagga
     8581 aagtacaatt tttacttaaa gatatacgat tggctcgacc taaaagtgca agtaatgaca
     8641 aactttcatt gaaattaatg tcaaaaataa taccaaaaga tactcaaagc ctgtataata
     8701 tatctgtgtc tgattttgaa ttatttgatg gaaatacaga tataaatata tttgattatt
     8761 ttgaaaaaga tacactaata atatctaatt ctataaatgg attttataga gcaatgtcag
     8821 atatatcact tatagatttg gattttaaca taaattacaa tattattgaa gatgttagca
     8881 aaaatactga taaattagag cttatatttt ctcctaatat tgataaaata gacttaaaaa
     8941 gatataataa tattattctt tatgattatt tatacaataa aggcgaatat tcgtatatat
     9001 atgagaataa aagagaagaa agtgaaatta taaaatatta taataaaaca gacctattat
     9061 atttaaagaa tgtagttagt aatatagttc catcaagaga tgaatttata acaatttata
     9121 aacaagcact cataaaaaaa gaaattgatt tggatatggt aaatataagg gaaactttta
     9181 atgtaattcc attaaagttt tttacgatat taaatgtatt tagagaatta aatttacttg
     9241 actttaattt aaattatgaa aaaaattctg tactcataag aatattgcca aaaccacaga
     9301 aaaaattaga cttaaatgag agtttaatac tcaataatct aaaaaattta gaaaaacaat
     9361 acaatagcag ttattaggag gcgtttccca tggatttaaa aaactttata aggaatattg
     9421 atgatttccc aaagccaggc atagatttta aagatgtgac aactctattt aaagatggag
     9481 atgcatttaa atatgcagtg gattctatag ttgaagaatt gaaagataaa gatgtagatt
     9541 tagtaatagg accagaagca agaggatttt tgatgggtac acctgtagca tatgctttag
     9601 gagtaggatt tgttccaatt agaaaacctg gaaagttacc aggtgaagtt gagagttatg
     9661 agtatggatt agagtatggt acagatactt tagagataca taaggatgca attaaaaagg
     9721 gtcaaaaagt agcaatagta gatgatttat tggctactgg tggaactatg gaagccgctg
     9781 ccaagcttgt agaaaaatta ggtggagaag tagtttctat gcaatttttg attgagctaa
     9841 aattcttaaa tgggagagaa aagttgtcta actatgatgt taattctctt ataaaatact
     9901 agtactttta taatagttgg tataacacca actattttca tatatattaa aattttatac
     9961 aaaataggtg gttatatgca tgataaagaa ttacaagaaa taattgaaaa aataaaagtt
    10021 tatgcaccta atgcaaattt tgaaatggtt gaaaaagcct ataatcttgc aaaaaaagcg
    10081 catgaaggac aatatagaaa atctggggaa ccatacttta ttcatccatt agcagttgca
    10141 aatattttaa tagagatgga attagatatt gaaactataa cagcaggttt acttcatgat
    10201 gttgtagaag atacagaata tacctatgaa gacataaaaa aagaatttgg caaagaagta
    10261 gcggatttgg ttgatggagt aactaaactt ggtcaaataa aatatcgttc gaaagaagaa
    10321 actcaatctg aaaatttaag aaaaatgttt ttggcaatgg cgaaggatat aagggttata
    10381 cttataaaac ttgctgatag actgcacaac atgagaacat taaaatacat gcctccagaa
    10441 aaagcaaagt ataaagcaaa agagacactt gaaatttatg gtggtatagc tcatagatta
    10501 ggaatttcca agataaagtg ggaactagaa gacagagcat taagatttat ggacccagaa
    10561 gggtattatg atttagttag tagagtatca atgaagagaa gtcaaagaga ggattatatt
    10621 caaggaattg ttgaacttct taaagataag tttaaagatt taagtatacc atgtgatgta
    10681 tatggtagac caaagcattt ttacagtata tatagaaaga tgcaaaaaaa acataagact
    10741 tttgaagaga tttttgattt aacagcagta aggatattgg ttgataatgt aaaggattgc
    10801 tatgcagtac ttggtatagt tcatacatta tggagaccta ttccaggaag atttaaagat
    10861 tatatagcaa tgccaaaacc aaatatgtat caatcattac acaccactgt tgtaggtcct
    10921 gatggagaac ctttagagat acaaataaga actcatgaga tgcataatat agctgaaaat
    10981 ggtatagcag cccattggaa atataaagaa ggtatctcta gcaaagagtc gaaggttgaa
    11041 gaaaaacttc aatggttgag acagatgatg gagtgggaaa aagatttaaa agacccacaa
    11101 gagtttatgg atgcacttaa agaagatgta tttaatagtc aagtttatgt atttacgcca
    11161 aaaggagacg taattgaatt accagcagaa tcaacaccta tagattttgc ctatagagtt
    11221 catacaaatg taggtaataa atgtgtagga gctaaaattg atggaagaat agttcctatt
    11281 gattataagc ttcaaaatgg taatattgtc gaggtactta catcatctaa ttctaatgga
    11341 ccaagtaggg attggcttaa tatagtgaaa accccaaatg caaaaagtag aattagacaa
    11401 tttttcaaga aggaaagaag agaagaaaat gttgaccgtg gaaatacaat attagaaaga
    11461 gaatttaaga agcatgatat accacaaaaa gaccctcttg ttgaaaaata tatggcatta
    11521 gttgctaaga aatttaatca gccaagtgtt gaggacttaa ttgccactgt aggttatggt
    11581 ggtataatgt catctcaagt ggtatctaag gtaaaagacc tatatttaaa agaggttaaa
    11641 aaagctaaaa aggaacaaca gatacaagaa gaagatttaa ataaacacaa tataagtgaa
    11701 acagaataca gtaaaaagag aaagaaaaac gcatcacaag gaattatagt aaaagggctt
    11761 gacaatatct tagtaagatt tgctaagtgt tgtaatcctc ttccaggaga tgaaattgta
    11821 ggatatatta ctaagggtag gggagtagcc atacacagag ctgattgccc aaatgcaaac
    11881 aataatggtg atttcttcca aaatagattg gtggaggttt catggagttc agcaggaaaa
    11941 ggtaagtttg aagcggaaat tcaaataaaa gctattgaca gaagaggaat tgttaatgaa
    12001 ataactcata ttgttgcaat ggataaactt agtttaaacg gaataaatgc aagaaaaggt
    12061 aaggatagta ttgtaagtat aaacttactt gtagaggtta atgacacaga ggaattaaaa
    12121 attctaatga aaaaattaaa agcaattcct ggtgtagaaa gtatttatag aatgacaaat
    12181 tagagttaaa ataataggga ggaaactatg agagcagtag tgcaaagagt atcttcatct
    12241 aaagttacag tagatgaaaa cactataggt caaataaata aggggttact agtattgtta
    12301 ggagtgactc atgatgataa atcaagtgat gtagattata tgattgataa aatattgaat
    12361 ctgagaattt ttgaagatga aaatgacaag atgaatttat ctctaatgga tataggtgga
    12421 gagcttttag tagtatctca atttacttta tatggagatt gcagaaaagg aagaagacct
    12481 ggatttagta atgcagctag accagaactt gcaaataacc tttacgaaga atttgtaaaa
    12541 aaagcaaaag ataaaggtgt gacagttggt acaggtcaat ttgcagctca tatgatggta
    12601 gagttaacta atgatggtcc agtaacaata ctattagact caagtaaatc tttttaaggg
    12661 ggaaaacttt aatgattata aaaaaatttg tagatagtta ttttggagta aatacttatg
    12721 tattaggtga tgaaaagact aaaaaatgtg cagttataga cccaggtgga agtttagtag
    12781 agacattaag ttttgtaaaa gaaaatgaat taaatattga atatattatc cttactcatg
    12841 ggcatggaga ccatatagga tatgttaagg atattaaaga aaaaactggt gctaaagtag
    12901 ttgcacatgt tgatgaaaaa gaattattaa atgacaaaaa taaaaatcta agttatacaa
    12961 tgagatgtgg agcacaagag tttgatgcag atatctatgt aaatgataaa gacaagcttg
    13021 aacttggtga attaaaaatg actttcttgc atactccagg acatactcaa ggatgtatgt
    13081 gtataagagt tgaagatgaa atgttcacag gagatacttt gtttgctgga agtattggta
    13141 gaactgattt atatagtgga gactttaacc aaatggaaaa atcacttaag aaattatgta
    13201 aatatgaaga tgctgttaga gtatatcctg gacatggacc aaccagtact ctaggagttg
    13261 aaaagaagac aaatccttac atgtaatttt atattagtat ttaaaaaagt ataaaatatt
    13321 taataactat attagtgagg gggttcttct actgttaaat agaaggagtt aagttgatgt
    13381 tgtatgtttt tttaaaagga catgattata agtatgaagt agcagaactt ataaaattgt
    13441 ttactagtga atttaagttt aaagactcta atgctaacaa taatatagag tcaaagcatt
    13501 taataaatag attgatttat gagaatggtg tattattctc aagtactgaa tactatgaaa
    13561 atggaaactt aaagtacgag tcaatacaga atatagaaaa tatgaatctt gaatttttag
    13621 atggatttga tagcagcaaa acgattgaag aatttcttaa tagcctagat agtgaaagta
    13681 agaggaactt taaaaagctg tgtaaagaaa atatcaaaaa aagcatgttt gtagtgctta
    13741 aacaagtatt taattcttat gtaccatggg gaattttgac tggtattaga ccagtcaaaa
    13801 ttgtccacaa tttaatggat aaaaagctag atgataatag cataagaacc attctaaaag
    13861 ataattattt tataatagat gagaaaatag atttagctct tgaaatagct aaaagagagc
    13921 gattatttat gtatcctata gataaaaata aaatttctct ttatgtaagt attccatttt
    13981 gtccaactag atgtgtatat tgttcatttc cttcaaattc attaaaacaa tttggacatt
    14041 taaaaagaga atatgtttat aaattgattg aagaaattaa ggggtttgcc aaagttatta
    14101 aggatactaa gaaagaagtt gaaactctat atattggtgg tggaactcca actacacttg
    14161 atgaggaaga attagatttg cttataaatt cattatttaa tgaattagat ttaagtaaga
    14221 ttaaagaatt tactgtagaa gcaggtagac ctgacactat tacagaacaa aaactaagag
    14281 tgttaaaaaa acacaatgtt agtagaatta gtataaatcc tcaaactatg aatgatgata
    14341 ccttggtaaa gattggaaga gagcatagag tatctgattt agtagattgc tttaatatgg
    14401 ctcgtagaat gggatttgat aatataaata tggatataat tttaggtctt atagatgaag
    14461 atttaaatat ggtaaagaat acattggagg agataaaaaa actttctcct gaaagcctta
    14521 cagttcatac attagccata aagagagcat ccaacttaaa tataaatatg gataggtata
    14581 aagaacatct aacacaatat gaagaaatgg taaaaatgat agatttatca atgaaatatg
    14641 caaaagatat gggattaaat ccatattata tgtacagaca aaaacatatg ttgggaaatt
    14701 tagaaaatat aggttatgct aaagaaggat atgagtgcat ttataatata cagattatgg
    14761 aagaaaaaca aagtaactat gcattaggtg caggtgctat atcgaaattt gtttatgtag
    14821 atgaagatag aattgaaaga gtagaaaatg taaaaaatgt tgaacaatac attgaaagag
    14881 tagatgaaat gataaaaagg aagaaagaag aggtatataa aaatgttgac taaagctcct
    14941 agaggaacta aagacataac tccaaaagag gcttacaaat ggcgttatgt agaaaataaa
    15001 tttagagaaa tatgtgcttt atatggatat gaagaaatgg taacacctat atttgaacat
    15061 acagaacttt tcaagagaag tgttggagat actacagata tagttcaaaa agaaatgtat
    15121 tcttttaaag ataaaggtga tagagaaatt accctaaagc cagaaggtac agcaggtgta
    15181 gtaagagcat ttatagaaaa taaattatat gcagatactc aaccaacaaa attattttat
    15241 gtgacacctt gttttagata tgaaagacca caagctggta gacaaagaca atttcaccaa
    15301 tttggaatag aagcacttgg aagtgatact ccttcaatgg atgctgaaat aatcgcacta
    15361 gctgttcaat tttttaatga agttggatta aatgatttgg tagtgagtat aaattcagtt
    15421 ggctgtccag tttgtagaaa agagtacaat gctttattaa aagagtatct tgactcaaaa
    15481 gctgatatat tgtgtgatac ttgcaatgag agaagagaaa aaaatccaat gagggttata
    15541 gactgtaaaa atcctacatg taaagaaaat atcaaagata taccatttat tgcagaccat
    15601 ttgtgtgatg attgtaaatc tcactttgat aaacttcaag aatacttaaa ggaaatgaat
    15661 ataaactttg taattgataa aacaatagtt agaggcttag attactatag aaaaactgct
    15721 tttgaaatta tatctaatga tataggagct caaagtactg tatgtggtgg aggaagatat
    15781 gatggtcttg ttgaacaatt aggaggacca aaaggtataa gtggaattgg gtttggacta
    15841 ggaattgaaa gacttttact tacacttgaa ggtaatggaa ttgaaataga aaaccctcaa
    15901 tctacggata tatttatagt aactataggt gaagaagcaa atacaagaag ctttaaattg
    15961 ttaaaagact tgagacaaaa tcatataagt gcagataaag accatataga gagaagtgtt
    16021 aaagcacaat ttaaatattc agataaaata aattcaaaat ttacaatagt aattggagat
    16081 gatgaactta aaaatgacac tgcgacatta aaaaatatga aaacatcaga gcaaactact
    16141 gtaaaattaa gtacattagt tgaagaatta aagcaaaagc tgtaaaataa gaaagtatga
    16201 tgttttgtgt attagataaa tatatagcat taaaattaaa taaaatggag gtagtatctt
    16261 ggaaacttta aagggtttaa agagaactca ctactgtgga gagttgagag aaaaaaacat
    16321 aaatgaagaa gttgtactta tgggatgggt acagaaaaaa agaaatttag gtggtcttgt
    16381 atttgttgat ttaagagata caagtggatt atgtcaaata gtttttgata cagatgtaga
    16441 taaagaagct tttgaaaaag ctgaaaaatt aggggctgaa tttgtaatag ctgtaaaagg
    16501 aaaagtatgc gaaagacaat ctaaaaaccc taatatgcca actggtgata tagaaatatt
    16561 tgcaactgaa cttagacttt taaacaagtc agaaactccg cctatttata taaaagatga
    16621 tgatgatgtt tctgaagcac taagattaaa atatagatac ttagatttaa gaaaaccatc
    16681 tatgcaaaga aatttaaaat taagacataa agtaatgaat attacaagaa attacttatc
    16741 aaacaataga ttttgcgaaa tagaaacacc atttttaata gctccaacac cagaaggagc
    16801 aagagattat ctagtaccaa gtagagttaa tccaggaaaa ttttacgcat taccacaatc
    16861 accacaatta tataaacaat tattgatggt aagtggtatg gatagatatt tccaaatagt
    16921 taaatgcttt agagatgaag acttaagagc agatagacaa ccagagttta cacaaataga
    16981 ctgcgaaatg tcttttgttg agcaagaaga tgttatgagt atgattgaag gtttgcttga
    17041 agcgatattt aaagaagttt tagatgtaga attggcactt ccacttccta agatgactta
    17101 tgcagaagct atgtctaaat atggttcaga taaaccagat actagatttg gatatgagtt
    17161 aacagatata tctgatgttg tttgtaactg tggatttaaa gtgtttgctg atgctacaca
    17221 accaggaaaa agtgttagag gtataaacgt aaaaggcaaa gctgacgact ttactagaaa
    17281 acaaatatca tcactagaag aacatgctaa gacatataga gcaaaaggtc ttgcttggat
    17341 gaaagtagga caagaaggag taacttctcc aatagcaaaa ttcttcaatg aagaagaaat
    17401 gaacgctata cttacaagaa tgaatgctga agtaggagat ttacttttat ttgtagctga
    17461 taaaaactca atagtatttg atgctttagg acaagttaga cttgaagtag caaataggct
    17521 taatctattg gataaaaatg tatataactt actatgggta actgagttcc cagtttttga
    17581 agaagatgaa gaaacaggca cattctcagc aatgcatcac ccatttacat cacctatgga
    17641 tgaagattta gacaagttag aagaaggtga taagtcatct ttaagagcga aagcttatga
    17701 tattgtattg aatggttatg aaataggtgg aggaagtgtt agaatatcaa attctgatgt
    17761 tcaatcaaga atgtttaaag cacttggttt tacagaggaa agagctaatg aaaagtttgg
    17821 ttatttatta gaagcattta aatatggtac tcctcctcat gctggtctag cttttggtct
    17881 tgatagactt gttatgttac ttgcaggaac tgataatata agagaagtta ttgcattccc
    17941 taaaaatcaa aatgctgttt gccctatgac aaatgctcct acattggcgg aagatgagca
    18001 attagaagaa ttaagtataa aagttgatat aaaagataat gaataatatg tagttgcaag
    18061 aaactaaaat gtaaaaagtc tggatataaa atatatttat attcagactt tttttattag
    18121 aattatttta tattttttct ctatatattt tcataaatta tacttatatt cttaaccaat
    18181 ataattaaaa tactatgttt aaaaatttta cataaacttg gttgttttag aaactacttc
    18241 tgtaatgagt acacgatttt aattaaagaa tatataacaa atttgaaata agtctaatat
    18301 atgacttaat agattaaatt aaaataataa atttggacta tttatctatt tataacttaa
    18361 attatatcaa attgataaca aactagatat tatacttttt tgtagaatag aattacaatt
    18421 atataaagaa aaattctatt aatagtgaaa aaaaagtaga aaaaagtaga aattattctt
    18481 ttataaagaa agggagggat aatattgcaa gagagagaag aattagtttt aaatccagtt
    18541 ccaaaagagg aaagagttgg atggttagct ccattgttta atatgcttgg ttctaacata
    18601 gctatatctg aactaatggt tgggggaact ttaattttag gaatgactct ttctaatatg
    18661 attattacat caattatagg gaacttaata ttagttgcaa ttattatgat acaaggttat
    18721 ataggttaca aagaagggtt aaatacgtat gtattagcta agggggcatt tggagagata
    18781 ggaggaaagt atcttatatc tctattactt ggtataacta gttttggatg gtttggtgta
    18841 caagcagggg ttgcaggact atcagtacaa aagatattcc caagtgtaaa cctaacatta
    18901 gttacagtta tacttggatt atttatggtt gtttttgcac tgtatggttt taaagctatg
    18961 gctaaattta attacttagt tataccacca cttatgatat taatggtgtg gggagttttt
    19021 aaagcttttt ctacttatgg agttgaagct atttataatt atactcctca aacaactatg
    19081 agtatagttg aaggtcttaa tattgtagta ggtcttgtta tagttggtgc aattatatca
    19141 cctgaccagt taagatatac gagacgagta aaagatattt ggattatcag ttttttaggt
    19201 ctagggatta tttcattatt ccaacaagtt gcagctggtg taatgtctat gggagcacct
    19261 acttgggata taacagaagt attggctaat ttaggttttg gatgggtagc gtttgttatt
    19321 ttaatacttg catcttggtc tacaaacgta tcaaatgctt attctggtgg attagcatta
    19381 aaaactattt ttccaaatgt aaaaagaaat gttttgactt tagttgcagg tctaataggt
    19441 acaataatag cagctactgg tataatattt aaatttcagt catttttatc tttcttggga
    19501 atcgcagttc ctgcaatagc aggaattatg tggtgtgagt attattttat acaaggaaga
    19561 acttataagc atagagaagg aataaattgg attgcagtaa taagctggtt aataggtttt
    19621 gcagcgtcgt attatagttc aaaaataaat ttcttaatac ctccgataaa tggaattgta
    19681 gtgagtatgg ttatttatta tatattaatg aaatgttttg gaatcaaaga taaataaagg
    19741 gggcaattac atgggtcgta aggtgaaaat aggtataatt caacaacaca gtgtacttgg
    19801 aaatgttaaa aaaaatatag aaaaggcagt agagatgata gatgacttag gaaaacaagg
    19861 agcagatata atttgtttac cagaactatt tgctacagga tataatttag agtctttagg
    19921 tggagttaaa acattagaat taataagaga acataataag tacatagagg aatcaatgtc
    19981 agaagctgct aaaagaaata atgtatacct gatatctcca tatggaacct tagaaaaagg
    20041 gtctacacat gtttataatt cagcagttat atttgataga aaaggtaaga ttatgggaga
    20101 atactgtaaa aatcatctgt ggtcattaga agcagtatac tttaaaggag gggaaaaagt
    20161 agaggtatat aatgctgatt ttggtagatt tggtgtaatg atatgttatg atgcaggttt
    20221 tccagaagta tccagagaat tgacattaaa aggttctgaa ataatattta taccatctgc
    20281 atggagaata caagatgaag atatgtggga tttaaatgta tctcaaagag ctttagagaa
    20341 cactgtatat acagtaggtg taaatttagt aagtaatgac tctaatttaa tactatttgg
    20401 aaagagtaaa atatgcaatc ctagaggtac tgtaataact caattagata catacaggga
    20461 aaaatatgta ttatcagaga ttgatttaga tgaaataaaa aagtataggg aagatatccc
    20521 ctatttgaaa gacagaaaaa gtagctataa catataattc tatactataa tacaagttca
    20581 atataaaatg ataaaaagag gatgtatcaa tattaagatt aaatttatta tactttgata
    20641 tatcctcttt aatattatca actttgattt aaatattttt aaaatagttg ataagaaagt
    20701 ttttgaacaa caacacagct ttagattcat agttttcgct aaaccatgaa agatttaaat
    20761 atcttttaaa ttcaatatct ttgatatgta acaacttaat ctcagggtct tgagataatc
    20821 cccatgattt tccacatata aatccaactc cttgaagtga ttttataaga gcataaattg
    20881 tatatggtga atcagactca aatgctattt tgggtttgaa attagctgat tcgcacagga
    20941 tatcaattac ctctctataa ttctcacctt tcgttataac tataaagttt tcatctgaaa
    21001 cttcgcttag atatacttca tcctttaatg ataaaggatg gtttattgaa actcctaata
    21061 gtatttcttc gcatgttaaa gttatgctat tttctgagtt tagctttgta aatgaagaag
    21121 atatgtacaa atcaaaatca ctttttttat aagatgatgg caaagtatgt gacacattaa
    21181 aagtaatgtt gggatatagt tttctgaaat tactcaaaag tgatggtaac acattagccg
    21241 ctgcaggaga taatatcttt acttctcctg aattttccaa agaagtgtct tgtaactcct
    21301 tttttgaact ttctactaaa tctaaaatgc tatctactct ttttagaaac aatcttccat
    21361 actcatttaa aacaatatat cttccttttc tgtcaaataa ctgaactcca agttcttttt
    21421 ctaaggaaga tatagttttg cttaaagctg gctgtgctat atttaacttg tgtgatgctt
    21481 ttgttatgtg ctccattcta gcaacagttt gaaaatactt aagatgcaat aaatccatag
    21541 tataaaatac acctctttta atatgacttg agttatatca attttataat caactccaca
    21601 ttatacatta taatataaag tttatataat aaactacaat atattaaaaa gttatttaaa
    21661 ttgttattta tattttgtac ataatctaat taaaaaaagt aactttaaat gattaactaa
    21721 ggaaatgttg ttacaaactt tagttatata aaaaattcat ttgatgagca aagtattaat
    21781 gtcaagtaag aataaaagct tattagataa gaaaaataat attttataat aatgatgtta
    21841 cttaaattat tatgttatac taatttaaat aggaaacatt tagatactat aattttaggg
    21901 ggagtcaaga tgaaattaac taaatcaata tcatcaatgc tgtgcttatc tctagtttta
    21961 agcttatcac cagtagcata tgcaaatgaa ataagtagaa caacagttga gaatacttta
    22021 gtaggtcagg atagatatca aactgctgtt gaagtaagta aaaaaggatg gagtagtgca
    22081 aatgaggctg tagttgtaaa tagtgaatct attgtagatg cattagctgt aacaccattt
    22141 gctaaattaa aaaatgctcc tatattattg acagaaaaaa ataatctaaa ttcacaaact
    22201 gagaaagaat taaaaagatt aggagttaaa aaagtttata taattggtct atctagttct
    22261 gtatcaaatg atgtgcaaaa acagttagaa tctaataatt taactactga tagagttggt
    22321 ggtagtgata gataccaaac agctttgagt atagctaaaa aaatagaagg attaaaagat
    22381 atatcagaaa tagctgtagt aaatgggtac acaggtcttg cagatgcagt tagtatagct
    22441 tctgtagctg ctactaatgg aatggttata cttccagtat ctgatgcatc tggtatatct
    22501 agctttaaag attttataga atctaagaat ataaataaat catacataat aggctctact
    22561 aatgctgtat cagataaaat aaaacaaagt ttacctaatt cagaaagaat aggtggagca
    22621 gatagaaatg aaactaatgg taaagtaata gaaaagtttt atacatctaa taaattaaac
    22681 aatgtatttg tggctaagga tggaataaaa aatcaaaatc aacttataga cgctctagca
    22741 gtaggagtac tagcatcaaa agaaaattct cctgtactaa tcgtaggaga acaattaagt
    22801 gcaacacaaa agagtgtatt ttcgaataaa aatgctacct ctataactca agttggtagt
    22861 ggaggaaatg aaaatgcatt taaagaatta aaagatttac aggcaaatag taacaataag
    22921 agagtaatgt atgtaactaa tacagataag gtaaatataa gaaatgatgc tacaatagaa
    22981 gcttctgtta taggatatct aaataatggt gatgaagtag aagttttaga tgtgttaaaa
    23041 actggatggg taaaaataaa atacaatgaa ggtattggat atgttagtgg gtcttatttg
    23101 acaaataata agcctgataa tagtaatgaa aatataaaaa taaagtatgt aaaagaaaaa
    23161 gatggtctaa atgttaggaa aggaccaagt acagaagatg aaaaaatagg tcacctttca
    23221 tatggaagca aagtagaaac agtagaaatg tttgctactg gatgggtaaa aataaagtat
    23281 aatggtggat atggttatgt aagtaatgat tacttatctg atacaccagt tatttaatta
    23341 taagtaacaa taaaaaaact gctttaattt gtaaagcagt ttttttataa aaatttaagt
    23401 ctaataacta tttctatttt gataccttaa tcctgggatt tattattatg gatattatca
    23461 acatacaaac actccaaatc cagtgtctaa ttccaaactt agatattaat aaattcagtc
    23521 ctgctatggt aaataagcag tatttaatta caattaaaag tgtatttata gaaagcccct
    23581 tcatagaaag tatcctaaat ccaataatag acattctaag tcctataaat gccaataata
    23641 tacctgcaat atcctgaatt aagtaatagt attcaaattt catattcaat caactcttct
    23701 ctgagcagta tcaaatattt ctaactcttc aatttcatca tctgtgtatg taagcatagt
    23761 aaaaccagtt acaccataaa taaatgaaat tataggtgta atccaactta agaaacaata
    23821 tggaataaat tctagtgggc ttacaccaag agtctgagca cagaaaacag catttgaatt
    23881 ccatggtatt aatggaccac caagtgtagc tgtatcttct ataattctag atagattttg
    23941 tggttttaat ttaaattctt tgtatattgg agacattaga gttccgacaa atacagaagt
    24001 gaacatcatt gatgaactaa atgcatttgc aaagtagctt actataaaag tagacccaac
    24061 caatttagtt cttgattttc ctattttagt tataagaggt tgaagcagta cttctaagaa
    24121 tccagttttt tggagaatac cagcaataac gaaaactaca aatactagta aaacggtttc
    24181 agccatactc attattccac cacgatttaa tagtttgtca gcatagacaa atccagtatc
    24241 tatagtaaat cctgatagca tgtaatttaa aacatcacct attttttctc cttcttgaaa
    24301 tactgctata ataagtccca tgatagctga acttagtata gatataatgg gtggcttttg
    24361 tagcaataaa agtaataata aaaatattat tggaatcatt gctactaaac caatatgaaa
    24421 gtttgaattt aatacatcct tgatttgatt tatttgaaca tagtctatag tattatttga
    24481 atacttaaat ccaattactg tatacagaac tatacatatt acgtatgcag gtcctgtggt
    24541 ataaaacata tgcttcatat gtgtaattac atctgtctta caaactgctg cagctaagtt
    24601 tgtagaatct gatagaggtg acatcttatc tccaaagaaa gcaccagaaa tgactgcacc
    24661 agctgttaaa ccaagaggaa tacccatact agtaccaata ctcatcattg ctataccaga
    24721 agttccaaga gtcccccaag atgtgccagt agcaacagaa gttaatgaac atacgattaa
    24781 tgttgtaagc agaaaatatt taggggttat tattgttagt ccactatata ctactgttgg
    24841 tattgtacca gcagctatcc aagctgctat tagtacacca acagaaagta taattaagtt
    24901 tgattgaaag gcatctttac caacttcaaa tccaaaagct tctatttcat cattagtata
    24961 accaagtttc atggctgcag gaactactat aagccatgaa agtaaaaaca ttgtagttat
    25021 agaagcatta aatacaacta taccaactga tgttagagct attattgcaa gcattactaa
    25081 caaggaatat ctaaatgaag gtatttttct ttctgtattc attttcatag tgcaaattct
    25141 ccttaaatat ttttagttaa ttgcattttt tattcttata agagcttctt caagcatact
    25201 tcttggacaa gctaagttta ttctttgata cccacttcct ccaatgccaa agctgtttcc
    25261 ttgatttaga gcaactttac ctttttgtac aagtatactt tctagttcct catcacttaa
    25321 tccaagtgca ctaaagtcta cccataataa ataagtacct tctggttttc taactttaag
    25381 ttttggcata ttttcattta tatattttat agcaaaatct atattagatt ctaaatattc
    25441 taaaaatgat tctagccaag attcaccatt attatatgaa gcttcagttg caactaagct
    25501 aaagcaatta tttctcttta tatcaattct ggtaaaggca tcatctaaca atttatagta
    25561 tttttcatca ggtagtatta catatgatga ttgaagacca gctatattaa aagttttagt
    25621 tggagccata caagtaattg tatttttttc aaattcttta gaaatagatg ccataggaat
    25681 atgcttatgt ttttttaata taatgtcact atgtatttca tcagatatga tttttacatt
    25741 atgcttaaga caaatatctc ctagtttttt taattcatct tttgtccata ctctaccaac
    25801 tggattatga ggattacaaa gtatgaataa ttttacatct ttaatcttgt tttcaatgtc
    25861 ttcataatcc attatgtagt ttccattttc taatttttgt aatgggctta taattagttc
    25921 tctattgtta ttttttacaa cactattaaa agggctgtaa actggttctt gtatcattat
    25981 tttatcattt gcttttgtga gttcatttat taaaagactt atagctggga taacacctgg
    26041 actataaatt aaccactcac tttttatttt ccagttatgt ctcctatcta gccagtttac
    26101 tatagattca ttgtaagaat ctggtcttgt tgtgtagcca taaatctctt gttctagtct
    26161 attttttaag gaatcaatta tacaaggtgc agccttaaaa tccatgtcag ccacccacat
    26221 aggaagtaaa tcattagttc catacttttt ttccatttct gaccatttag atgaaaaatt
    26281 attgcttcta tcaacaatct cattaaaatt ataattcatt gtaaatacct ccagtaattt
    26341 taattttatg ttaataatat taagcaaaca acgtgccaat attgataata aaaaatattt
    26401 attcacaagt taatatttaa tattaagtaa tttcagagca tagataagat aaaaatatta
    26461 attatactta aaactttgtg gaaaaggtta tttctaataa atttttaaat atatgaaaat
    26521 gtaattaaat aggttaaata ggtttaactg tttaacttgt tagacctatt tatatttttt
    26581 agaaattcta ctccttttga tgttataatt gaacctccac gaccaacaag tatgtctaca
    26641 agcccaaagt cttgtagttc taaaagcata tttctaatct gttgttctgt caaaaatcta
    26701 ttttcctcta aagctatttt acataagctt tttctaccta ttctttcttt taaatcataa
    26761 gcctttttta aattatccaa tataaatatg tattcatcta gtgacttttt aaaattatag
    26821 tcgtatttca tgatgttttt gtctttgcca atgttgaatt gatacttttt tatattatca
    26881 cttactttat tacaaacggt tctactataa tttgaatcta tagtatccaa tatatattca
    26941 ggtaaatcac atatttctat aatatctttt tccaagtaac agaaatattc tcctaagttt
    27001 cttaattctc ttacatttcc ttcccatcta tacattttaa agatttcttt tacttcctca
    27061 cttagaataa aattacatgg aatatcatat tttaatgaac caaaaatttc aaatatatca
    27121 gcaggtcttt ccctaagtgg atgtatttta aggggaagaa cattcaacct aaaatataaa
    27181 tctcttctaa acatattttt agatacaagt tcttttaaat ttctattagt agctgcaatt
    27241 attcttacat caatatcaat gacattatta gaaccaatac gtcgtacttg tttttcttgt
    27301 atgactctaa gtaatttaga ttgagaattt aaatccattt ctccaatttc gtctaaaaat
    27361 atagttccat tgttggctaa ttcaaataaa ccaattttcc cacctttttt agcaccagta
    27421 aaagcccctt catcatagcc aaataattca ctttgcagta gattttcttg aaaagtacta
    27481 caatttactg cgacaaaagg accatctttt ctcctagaag cactatgaat ggattgagca
    27541 aataattctt taccagtacc actttcacca attataagga tagatgaatt tgattgagcc
    27601 attttattag caattttttt tgtattaata gtttgtatac tagaacctaa tatgtcatca
    27661 aatgtgtatt tactgatatt accagagttt actagttgtg ctcttaattt agcttgcttt
    27721 ttttctaatt gagaaaactt tgtcatcttt agtataaatc catcaaatac atttaattgt
    27781 atatgtttaa tctctaaatt tatatcaata tgatttattt taatcaattt ctcaaaaaat
    27841 ggagttttat tggtcaatat gctttgaaaa ttgatgtctt ttatgcaatc accaacaaat
    27901 gagtcaatca tttcatttgc atttatagac aaaatttttc tagccatatg attatagaat
    27961 tgaattattc catcgttatt tgtgcatata attccatcat caattataga tagcaacaaa
    28021 tcaaattgtc tttcaaactt atttgcatct aacaataact cacctgtact ataacttgta
    28081 ggaattattt tttctacgta tttttttatt aggtcatctt ttattagatg ttttaatttg
    28141 gtttttgtag caatttcaac aatacaactt aaatctatta ttctgtattt taaatctata
    28201 acttcacaat ttttaaactt aggcaagatt ttttcgccag gagttaggat tacagcatct
    28261 gtgggagtaa actcaatctc tggatagcag ggcaggatat ttatattgtc tattcctaat
    28321 ctatgtatta aagaaattgt ttctattgcc atatctttac ttaagttata tacataaata
    28381 attttatctt tttctaattt ggatatcata tcaatactgt tcttttcaaa tgtcaacttg
    28441 ggaacaatga tttgagcatc atagtgagat aattttacta tttcatcata ttttaaataa
    28501 gcagatagga gtataagttt ttctttaaaa aactttaaat tcccctcttc aaatgagtat
    28561 aaatttatct ttagattatc acctaagaat tgccttattt gattttcata aatttctcca
    28621 gcgtcttttt ttaaacttac aatagctaat tccatttgtt tcattttaac ctctcataca
    28681 aatttgactt attttagatt acataataat taaattagat taaataatat tatttaatta
    28741 ttattataaa tttattatag actgcacatt gaagtaaaag aagtagctaa aattattcct
    28801 tttatttttg ttttttgtat ctatttggta taatagtatt agagcgtata ataatttagg
    28861 caaaattttt taaggaagac tagaggagaa tataaaatga aaaaatgtct ttactgtaat
    28921 agggatataa agtcaccaaa taataaatta gctataaaat atgatgacaa tatgaatata
    28981 tatccatgtc gtgcagaatg taaggaaaaa attgaagaat atatagcaaa aaaacctaca
    29041 tataagttta taaatatatt agaggttctt ttaggtgtgg gcggaatatt ctgctttttg
    29101 agtaaatgga ctattgcagc ccaagttgta cttggaattg atgcactggt tatattttta
    29161 ttcccattgg caggatttaa gatgaatgga aagttaagta tggaacaaac taagaatcaa
    29221 agtaggtcta ttgcaatatc aattttggca tttatagtaa taataactgt attatatttt
    29281 aaacaagttg gtaagtagag cataattgta taagacatca ttagagtatg aggtgagttt
    29341 atggaagaaa gaaaattagc accaaacaat gagagggaag ctctcataaa aagattaaaa
    29401 agaatagaag gtcaagttaa gggtatacaa aagatggtgg aacaagaacg ttattgtgtt
    29461 gatatattgg ttcaaatatc tgctataagg tctgctataa atagagtagg cacaattatc
    29521 ttagagaatc atataaaagg atgtgtagca gaaagcatta aacatgatga tgctgataaa
    29581 actgaagaga tgataaaaga gcttatggat actataaata aatttacaaa ataaggaggc
    29641 ggttagttat gaatcaacaa ggatttatta tggaaattgt tgatgataga actgcaaagt
    29701 taaaaatgca aagacattca gcttgtgctg cttgtggaaa atgtgctact acaaattcag
    29761 cagagtcaaa agaaatatta gtagaagtag acaacacaat tggtgcaaaa gttggtgacc
    29821 atgtagaagt gagtatggat aatatgaatg tattaaaagc agctgtaatg gcttatataa
    29881 tacctcttat agcacttctt gtaggaacaa tagggactta ttatatattg ggggcaattg
    29941 gaatgacaac tggagttgaa gccataagtg gattagttgg aatttgtctt acaataatct
    30001 gttatttata cttaaagaag aatgacaaaa aatttagaga cagtagagaa tttataccag
    30061 taataacaag aatattaatt gacctttaag ataattataa ttaaaaaata gcaatgtact
    30121 ttttaaataa atactcaata cgtatttgta gagtttaagt acattgctat ttttatattt
    30181 ttattttgat tttctgtaag gaataaagtt ttttctgatt tttaaaagat tcaatgttct
    30241 tacaaaagaa gttacaacta atacaccaag tgctattgca gcacttagaa atagcgcatc
    30301 tgtacctttt gacatagcca aagaataatt tttctgaatc aaagacaaca ttgtattata
    30361 tagcccaatt cctggtatta gaggaagaat acctggaatt acgaacacaa tagctggttg
    30421 ctttagtttt cttgctaaag tctcactgca cgctgagacc aaagcagcag cgataaaacc
    30481 tgcaaaaact gcatttgtag taaaattaaa taaataaaca tatacaatcc aaccaattcc
    30541 gccagttact ccagctggaa gaagtagata tagtggagca ttaaagaaaa cagcaaatcc
    30601 agcagttgca acacctgaaa ataaaaaatg caaaatcata gacatatcag tcattagaaa
    30661 ggacctccta ttctatacca tgtatcaagg acaaaaccaa ctccagaagc aattgcaata
    30721 ataatcatag cagcatcaaa agcacgagaa attcctgata ttaaattccc tgatattaaa
    30781 tctctaatag cttttataaa agcaactcct gggagtagtg gcattatagc gccgactata
    30841 agcattttag ggtcatctaa aatgcctatt tcaactagta gaactcctga aagtgcaatt
    30901 aaaaaagaag atactaaaca ggaaaatgca gatattgcac ttatcttcat cgttttatca
    30961 taagtaattg cagcaaagat tgctattata aacgtaagta taaaatttaa tacataattc
    31021 cctccaagca aacaagcaaa acaagcagat gcaattcctg tacaagagta aaataaccat
    31081 aaaggataag gttttacatc ttggatttca taaagacgtg caatggcatt atcaatatca
    31141 tactctttgt cactaacaaa ttctcgagaa aaactgttta ataaagaaat cttatttaag
    31201 tttatacctc ttgattgaat cgttttcata aacgaaaagc catcaaattt ctcatctgaa
    31261 ataattatta ctgtaggagt tgtaaaaata tttacatgat aaaaccctct tgacctgcat
    31321 attctaagga cactgtcttc aaccctagat gtttcagctc cattttttat catcagttcc
    31381 cctacaaata gagctagttt tagaatattt ttcttatatt caagttcctc attttgattc
    31441 ataaatacac ctccaaatta aaaaacgtaa tattgaaatt atatcaaatt tttaagtaat
    31501 attccttaat atctatataa atatattatc ttttttttgt ttcaaaatag tcacatttaa
    31561 attatatcca attaaaagaa ttagacaata ttatttatta tattttaact taaaaataaa
    31621 gaaagtaact atgttaaata tggaaaaatg gcaaaacact tgactattaa ttggtaaagg
    31681 actataataa taaattatca tattgataaa aacgaaaatt atgaaatgtc tgtaaaaata
    31741 aaatttaaat aataactagg aggagtaata tgtttgagaa cttgaaaaaa gcggaccctg
    31801 agatttatga aagtatgaaa agagagttaa aaagacaaca aagaaatatt gaattaatag
    31861 catctgaaaa catagtatca gttccagtaa tggaaactat gggaagtcat cttacaaata
    31921 agtatgcaga aggttactca ggcaaaagat attatggtgg atgtgaatac atagatgaag
    31981 ttgaaactct tgcaatagat agaatcaaaa aaatatttgg agcagaacat gctaatgttc
    32041 aacctcactc tggagcaaat gcaaatattg gtgtatattt tgctatgtta aaaccaggtg
    32101 atgttgttat gggaatgaat ttatctcaag gtggacattt aactcatggt gctccagtta
    32161 atatttctgg tcaatattat aaattttatg aatatggtat agataaagac agtggactta
    32221 tagattttga tgaagttaga aagatagcac atgaagtaaa acctaaaatg atagttgcag
    32281 gagcaagtgc atatcctaga gaaatagatt ttaaaaagtt tagagagata gctgatgagg
    32341 ttggagcatt gcttatggta gatatggctc atatagcagg tcttgtggct gctggtcttc
    32401 accaaaatcc atgtgaagtg gctgattttg ttacaacaac aactcacaaa actttaagag
    32461 gacctcgtgg gggtgttatt ctttgtaaag aaaaatatgc taaagacata gacaaagcaa
    32521 tattccctgg tattcaaggt ggacctcttg aacatataat tgcttctaag gcagtttgct
    32581 ttaaagaagc tttaagtgat gagtttaaag aatatcaggt acaagttgct aaaaatgcaa
    32641 aagccttagc tgaagaactt attaaaagag attttaaatt gatttctgga ggtacagata
    32701 atcatttaat actattagat ttgactaata aaaatataac tggtaaagca gcagaaaaga
    32761 gattggatga tgcttatata acagctaata aaaatacaat tccatttgac ccaaatggtg
    32821 ctcttgttac aagtggaata agacttggta ctccagctgt aactactaga ggtatgaaag
    32881 aagaagatat ggcaataatc gctgaggcta tagacctatg tttaacttat gatgaagaat
    32941 ctaaggctag aacattggtt gttggtttaa ctgaaaaata tcctttatat gaagaatata
    33001 atattatgga ttaattataa agaacaacta aataaaatac atttaaataa ttacaatgat
    33061 tgtgtatgta tttgaatata tttagatata aaaaaggtgt ctcaaaatga actttttagt
    33121 ttatgaggca cttttttgta tggaatcgaa catatttgta ttatttaaat aataaaaaat
    33181 atggttatct ctatttttag atggtctctt tgtatttttt aattaaaact ttaagatttc
    33241 ttaagaatta tactaggttt ttctaaagat ttaaagtcta tacttataag tatagtaatc
    33301 atatgaaaag aaaagcttta acgaggaggg aatcttatga aggtattaat tcttacagga
    33361 aaatttggta tgggtcatta ctcagcatca aattctttaa gtgaagatat aaaagcaaaa
    33421 tttgataatt cagaaataat aattaaagat atatttgagt acattatgcc taactattca
    33481 gataaaatgt acaagacttt ttctattctt gtaaatcggg gaagtagtct ttataattta
    33541 ttttataaat gtgctgaaaa tggaaagaaa gatataaaat ttactttttc agattatttt
    33601 ttaaataaat tagatacatt acttcatgaa gtacaaccaa cagtagttat ttcaactttt
    33661 ccattttgtt ctcaattagt atcaagatat aaggaaaaat ataactcaaa tcttccttta
    33721 ataacatgta taactgatat aagtagtcac tcagaatgga ttagtaaaaa tacagactgt
    33781 tatttagtag ctagtaaatc tactaaggaa gaacttgttt ttaaaggaat agatgaatct
    33841 aagattaaag ttaatggtat tccagtaaaa aaagaattta aaagaataga acatgtaaat
    33901 cattcaacta aaaaaaatat tcttataatg ggtggaggat taggattact gcctaaatca
    33961 gaacaatttt acaaagaatt aaatagttta gaaggagtaa aaactactgt aataactggt
    34021 aataataaaa aaatgtacta taaactatat ggtagatatg aaaatataga ggtagtaggt
    34081 tacaccaatg aagtatataa atatatgaaa gattctgacc ttattatttc taaaccaggt
    34141 ggaataacac tatttgaaac aatttattca gaacttccaa tattggcatt taatccattt
    34201 ttacaacaag agatagataa tgctagtttt atattaaata atgaaattgg gagaatactt
    34261 ggtaaaaata aaaaatacta tgtagatgag ataaaagatt taatttatga tgatgctact
    34321 cttaaagaaa tgagcagtaa catgaaagaa ttaaaaaaac aatttgataa taatacctta
    34381 gagaatattt tattttcact tgatgaacaa ggagcgtgta gagaatgtat gtagtaggtt
    34441 taattatcgt tgttgcattg atttttttag tccattcaat tatacctaca tactataata
    34501 aactattaaa taaagaggta ttaaaaaata tggctggaga aaatgaaatt gcacttacat
    34561 ttgatgatgg tccagataag agatatacag aaaaattact agatgtgtta aaagaaaatg
    34621 atatacaagc tatgtttttt gtagtagcaa agaatgctga aaaagagcct gaaattataa
    34681 aaagaatgtt gagagaaaat catatagttg gtttacattc attggaacac agaaatgcat
    34741 ggctttatag ttatagttat gttaaaaaag attttattga aagtacaaat ataatgaaaa
    34801 atttaggtgt agatgtaaac tactatcgtc caccatgggg tcatactaat atattttcaa
    34861 attcatttgt taaaaaatat aatctaaaaa tgactttgtg ggatgtaatg gcagaagatt
    34921 gggagaaaga tagtacagta gacattatta taaacaagtt aatgagtaga acaaaagaaa
    34981 attctataat ttgtttacat gatgcaggtg aaaattcagg tggtgcagta ggtgcacctg
    35041 agcgtactat tgaagcttta aagatagcta ttccaaaact taaagccagt ggtttaaagt
    35101 tcgtaacacc agaaaggatg tagttatgat aagtaaaact gaaaagaaaa ataaatgcct
    35161 aggtagtgta gcttttttag ttttactaat gggcataaca ggatattttg tttttagagg
    35221 gcagtcagtt gaatcattga taaaatcatt aaaaggtgca agccctatgt ttatactaat
    35281 tggatttgca atgatgttta tatatgttgc ctgtgaaggt ataaatatat acttaggtat
    35341 gaaagcttta aaccaaaaga ctactctttt aaaatgtatg ggatatgctt ttattggatt
    35401 ttattttagt tctattacgc cttcagcatc aggtggtcaa ccagcacaag tttattatat
    35461 gaaaaaagac gatataaata tatcatattc ttcacttata ctattagtca ttgttgttat
    35521 tcaccaagta gttatactgg catatagtgg aataatgttc attatggaac gtgagtttat
    35581 attaaataat gtaagtggta tgaacatttt actaatatat ggtgtaataa caaatgttgc
    35641 tcttgtcatt ggagtaattg caattatatt ttcaaaaaaa cttgtaaaca attttataat
    35701 atcaataaca aatttattag gtaagttaag aataataaaa gatgttgaaa gttcaagaaa
    35761 agttataata tctcaaattg aagagtatgt taaaggtgct caatatataa agcagaatcc
    35821 aaaacttgta gtccaaattt tagtcataac tattgtacaa ataacagcta tgtttttagt
    35881 tcctttcttt gtatacaaag cttttcatct atcaacatat actgtatttg agatattagc
    35941 gatacaatcc ttgcttaata ttgctgtttc ttcattacca ttgccagggg ctgttggagc
    36001 ttctgaaaat agttttatga cattatttaa gatatttttc cctggtcact tattagttcc
    36061 ggcaatgtta cttagtaggg gaataagttt ttatgcattt gtagctataa gtggattgat
    36121 atgtatagta gtacatgtaa aatcttctga aaaagtaaaa gcagtgaaaa aagttgctta
    36181 tgtaagataa tattatatag attattttta ttaatatgtc aatttgtgtg tatattttaa
    36241 ttaagcttta aacatgttta caggagtaga aactattaaa acgtgtgaca ttgctaagct
    36301 tttgctaata aagtataata ttttatatag tttgaaatat ttaagaaata tagcaaaaaa
    36361 aggagcttgg tgatgaataa agagattcca aaaaaaattt tagtagctga tgataatcct
    36421 gagattaggg aaatcgtaga aatactttta actggtgaag gttatgaagt tattatggca
    36481 acgaatggag aagaagctgt aaacttagta gatagtacga ttgatttgat tattttggat
    36541 gttgtaatgc ctgtaaaaac aggatttgtt gcatgtaatg aaattagaga aaaaacgaca
    36601 gcaccaatat tatttttaac tgcaaaaact caagactctg ataaagttat tggattttca
    36661 gcaggaggag atgactattt atcaaagcct ttttcatatt ctgaactaat ttcaagggtt
    36721 aagtcgctac ttagacgtta ttatatatac cagggaaagg aaaaggaaag agagccaaat
    36781 atattaaaaa caaaagagtt atgtgtcaat ttagatagtc aagatgttac actaaatgga
    36841 gaacctgtgt ttttgacaac tatagaatat agtatattaa ttcttatgtt gaaaaataga
    36901 aaaaaagttt tttcgtctga aaatttatat gaaactattt gggatgagca gtatttttat
    36961 acagcaaata atacaataat ggttcatatt agaaatttaa gaaaaaagtt agaaaaagac
    37021 caaaaaaatc cacaatatat aaaaaccgca tggggaaagg ggtattatat tgattaacaa
    37081 aattaagcca tctaagttgg gagttatact attgatatat gtagtaatct cagctgcagt
    37141 ggctttcatt ttaaatatac cattttactc tgctgttgaa tctatagtaa aagatgtatc
    37201 agaagggaaa gtatatttta aaagagaagt aaatcaactt atggataatt ttcaaactta
    37261 tgtgaataac aatggtataa gagcagatga tggagatgat atagcaaaat ggaatagtga
    37321 taattggttt gtttctatga agatatataa aggaaataag gttttttatg atacattata
    37381 ctatcctaat gaagtacctg ataagagtga ggaaaatgag ttttatagca gtcccatggc
    37441 tagaaactat gagatacaat tttctgatat taaagctaat atagttgtag tagctttatt
    37501 tagatttaga tttcaaaatt ttatagaagc aatttctatt acatttatgg cacttacatt
    37561 tattataaca tttttactgt tgtttagtag aaagataaag tacctaagga aaatagaaat
    37621 gggtataaag atagtagaga gtggcagttt aaagtataga ataccagtaa aaggtaatga
    37681 tgaattatca tcacttgcat ctagtattaa tgagatgagt catacattgg agaatcaact
    37741 tataaaagaa agggagatga agaataaaaa taaagatata gtaacttcaa tatcacatga
    37801 tgttagaact ccattaacgt cagtaatttg ttatttagat ttgattaaag accataaata
    37861 caatagtcct gagcaattgg aacaatacat aaaaaatgta aggtctaaag catatcaaat
    37921 aaaagattta acagatgacc tttttacgca ttttgttaat tctggagagg aagtttcaaa
    37981 agggtatgaa aaaataaatg ctaatgaatt tatttttcaa ttacttttag atagttcata
    38041 tacattggag gagaaaggat ttcatataac aatagaaaat gaactttata accaatatca
    38101 tatttatgta gatgttacac aatttagaag gatatttgat aatttatgtt ctaatataat
    38161 aaaatatgct aggaaagata agcctatagt atttttaatt aaagtagagg attctaaatt
    38221 actaattata caaaaaaata gagtaagtaa tttttctaag aatgtagaaa gttttggaat
    38281 tggtataaag aattgtgaga aaatagttgc atatcataat ggaagcataa atgtaaattc
    38341 agatgataaa gaatttgcta ttgaaatatc tattccagca aaagaatcat aaaaatttaa
    38401 attatatatt gtgtaattgc ttatgtaaaa ttctatgaag caggaagcat gtgactttag
    38461 ttatgggatg ttcaatattg tgtacctcta ggcaagtaac aagtttactt acaagaccat
    38521 ataatattat tatcttaaaa aaaggggaca taataatatg gttttgacag gagcacatta
    38581 tatttacatt ctatttatgg taattatatt aattactatg attatgaaaa aggatacaat
    38641 agtaccatgt atattaggtg ttttttttat ggggttgttc tttgaaagaa acatttttgg
    38701 tgctataaca gcagtgttta actcttttat tatatcttta aatgagttgg gtccaattat
    38761 cttgattata gctattatgg ttgcattatc taaagcccta gaagccaata atgctataca
    38821 gtatatggtg agaccatttt cgagagttat aaaaaattct aatacagcat tttttgtaac
    38881 tggatttgtt atgttagttc tttcttggtt tttctggcca actccagctg ttgccttagt
    38941 tggagctgta tttttacctg ttgctatgag agctgggcta ccagcaattg gtgttgcagt
    39001 agcattaaat ttatttggtc atggtcttgc cttatctaca gactttgtta ttcaaggagc
    39061 tccaagtata acagctggtg cagcaggtgt tgcagtatca tatgttataa atgatggtat
    39121 gattttgttt tgggtgatgg gaatcgtaac catatctatg gcattttata cattaaaaag
    39181 agatattaac aaaggaatgt ttagagaaga actaaaaggt tttgaaagtg aagaagtaga
    39241 agagttcaat ggaaaatcta aaatagcaac tattttagta gctctgggat ttcttgctga
    39301 tataattgct atgtatgtat ttgacctaaa aggaggagat gcatcagctc ttttgggtgg
    39361 aacagcagta tttttaataa taattataaa tgttataaat tttggcaaag atagtcttga
    39421 aaatgtatgt gagaatataa ttgatggttt tgtgtttggg ataaaaatat ttggagcaat
    39481 tataccaata gcagcatttt tctatatggg tgaagttgca ccattgacaa gtgtatttgg
    39541 aaaagtatta gcaccaggtt cacaaggttt attatcagat ataggcatag ctctttctca
    39601 aacaatacca cttaataaat ttgccgtatc aggtatagaa actgtagtgg gagcaataac
    39661 tgggcttgat ggttctggat tttctgggat ttcattagtt ggttcacttg cctctgtatt
    39721 tggaactgct ataaatgcaa gtgttggtgc actagctgca ttaggacaaa tcagtggtat
    39781 atgggtaggt ggaggctgtc tagttccttg gggtcttatt tcagcagcgg caatttgtgg
    39841 agttagtcca atagaattgg caaagcgaaa ctttgtccca gttataaccg gattggttgt
    39901 aacaaccata gtagcaatgt ttattattta ataaatcgaa taaatcttta attgtataaa
    39961 ttaaaaatag atgtgtagct ataatttatt ataattgttt tactaattct aagccataca
    40021 tctattttta ttgatatttt tattagtatt ctttaataaa ataatatttt tcattatact
    40081 atacataaca tctaaatata acatctaaaa tactgttatc tatatttaat atcttgccaa
    40141 attttttgat gttttattgc cctgtcccac caacatatat aagctatcac aagtttttac
    40201 ctatactatc accaaacaaa aattctaatt ttaatttatt attttataac ctatattata
    40261 ttaactatat tagtttgtag actttagatg taattataaa tattaatact ccaagagttc
    40321 aaattcatat cctagttttc ttgcatttga tataaaatca tttaaaattt ctgtactagt
    40381 tttggaaact gcatgtagta acaagataga accatcatgt agattatcca ttattttttg
    40441 cgttgcttct tcatgtgatg gttgtttatc agtatcccag tctctgtatg caaaactcca
    40501 aaatacagtc ttgtatccta aatttttagt cattgccaag cttttttctg agtattttcc
    40561 cataggaggt ctaaaaaatt taaccatatc tttcccagtt acatctttat ataacttttc
    40621 aacatcatat aattcgtcat taaagttttt tagattgctt gtttttgttg gcatagatgg
    40681 atgggtttta ctatgatttc caactatatg tccctcagaa accattcttt ttactaaatc
    40741 tttattttct tttatatatg gagctgtaac aaaaaaaact gctttaacct ggttttgttt
    40801 tagagtgtcg agtatctttg tagtgtatcc attttcataa ccttcatcaa atgtaagata
    40861 tagtgttttt tgaccatctt ttgtaggtcc attgtatagg gcatcatagt cagaaaattt
    40921 aaattcaatg tctgtattta cttctggtgt tttatgctta ttgtttggta tataaaacca
    40981 atcaagagta gtgttatcta aagaagatac atctaattta ttattatcat tattagtagt
    41041 ggcttttgat ggtttatctg ttccgtctga aactattaca ttggaagtat ctttaccact
    41101 atctattttt tccttatctt cttgtaactg tgtttcctta ttttgatttt cgttttgatt
    41161 gttttgtgaa tttgaacatc caacaataaa aaaaatagaa atagaaagta gtgttaaata
    41221 atgcaatact tttctaaaca ttttgaagct cctttctaaa ttaataataa ttgcatataa
    41281 taataattat atgattaatt acaattgcat atagtattat tataattgga aattactatt
    41341 aataatagtt atatctttaa aaataaagtc acaatagtat gacaaagggt gaataatcaa
    41401 taaatttaaa aaaaaatgaa aaaaatagtt gaccatatta tgagaagatg ttattataat
    41461 aaatgtgctc aacaagaagt aacaaaataa caagcacaaa gaagttaatt gaat
//
LOCUS       DAEQAF010000028        39898 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.029, whole genome shotgun sequence.
ACCESSION   DAEQAF010000028 DAEQAF010000000
VERSION     DAEQAF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 39898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.029"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            124..1182
                     /locus_tag="KRN00_001545"
     CDS             124..1182
                     /locus_tag="KRN00_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1827412.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            1433..3577
                     /gene="fdhF"
                     /locus_tag="KRN00_001546"
     CDS             1433..3577
                     /gene="fdhF"
                     /locus_tag="KRN00_001546"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1847..1849,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HBH1827413.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLEEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            3626..4459
                     /gene="fdhD"
                     /locus_tag="KRN00_001547"
     CDS             3626..4459
                     /gene="fdhD"
                     /locus_tag="KRN00_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBH1827414.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYVNTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNLLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            4470..4643
                     /locus_tag="KRN00_001548"
     CDS             4470..4643
                     /locus_tag="KRN00_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827415.1"
                     /translation="MCTKKEKQRYSKCEICGVLIDDTDKVYNNTYNLCKKCKRNISTE
                     KIVKYINIYDESK"
     gene            4701..5252
                     /locus_tag="KRN00_001549"
     CDS             4701..5252
                     /locus_tag="KRN00_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1827416.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNIQAALSLLLTNK"
     gene            5277..6653
                     /locus_tag="KRN00_001550"
     CDS             5277..6653
                     /locus_tag="KRN00_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH1827417.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            6653..7168
                     /locus_tag="KRN00_001551"
     CDS             6653..7168
                     /locus_tag="KRN00_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1827418.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(7246..8529)
                     /locus_tag="KRN00_001552"
     CDS             complement(7246..8529)
                     /locus_tag="KRN00_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBH1827419.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     KISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            8717..9139
                     /locus_tag="KRN00_001553"
     CDS             8717..9139
                     /locus_tag="KRN00_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBH1827420.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            9241..10179
                     /locus_tag="KRN00_001554"
     CDS             9241..10179
                     /locus_tag="KRN00_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBH1827421.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFATEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKYYIMENKPVDNVVDISRGY"
     gene            10365..12389
                     /gene="ligA"
                     /locus_tag="KRN00_001555"
     CDS             10365..12389
                     /gene="ligA"
                     /locus_tag="KRN00_001555"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBH1827422.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKRIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTIKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKEMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            12549..13898
                     /gene="rph"
                     /locus_tag="KRN00_001556"
     CDS             12549..13898
                     /gene="rph"
                     /locus_tag="KRN00_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBH1827423.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNVHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            13898..14368
                     /locus_tag="KRN00_001557"
     CDS             13898..14368
                     /locus_tag="KRN00_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1827424.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            14562..15848
                     /locus_tag="KRN00_001558"
     CDS             14562..15848
                     /locus_tag="KRN00_001558"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBH1827425.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            15998..16582
                     /gene="clpP"
                     /locus_tag="KRN00_001559"
     CDS             15998..16582
                     /gene="clpP"
                     /locus_tag="KRN00_001559"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH1827426.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            16601..17851
                     /gene="clpX"
                     /locus_tag="KRN00_001560"
     CDS             16601..17851
                     /gene="clpX"
                     /locus_tag="KRN00_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBH1827427.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(17922..18449)
                     /locus_tag="KRN00_001561"
     CDS             complement(17922..18449)
                     /locus_tag="KRN00_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1827428.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(18437..18949)
                     /locus_tag="KRN00_001562"
     CDS             complement(18437..18949)
                     /locus_tag="KRN00_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBH1827429.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            19129..21492
                     /gene="lon"
                     /locus_tag="KRN00_001563"
     CDS             19129..21492
                     /gene="lon"
                     /locus_tag="KRN00_001563"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBH1827430.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLGNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            21482..22093
                     /locus_tag="KRN00_001564"
     CDS             21482..22093
                     /locus_tag="KRN00_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBH1827431.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(22358..23728)
                     /locus_tag="KRN00_001565"
     CDS             complement(22358..23728)
                     /locus_tag="KRN00_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1827432.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     regulatory      complement(23903..24018)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            24306..25385
                     /locus_tag="KRN00_001566"
     CDS             24306..25385
                     /locus_tag="KRN00_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1827433.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     gene            25776..26456
                     /locus_tag="KRN00_001567"
     CDS             25776..26456
                     /locus_tag="KRN00_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBH1827434.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSAEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            26449..27828
                     /locus_tag="KRN00_001568"
     CDS             26449..27828
                     /locus_tag="KRN00_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBH1827435.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            27999..29084
                     /locus_tag="KRN00_001569"
     CDS             27999..29084
                     /locus_tag="KRN00_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBH1827436.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            29138..29497
                     /locus_tag="KRN00_001570"
     CDS             29138..29497
                     /locus_tag="KRN00_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBH1827437.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            29550..30422
                     /locus_tag="KRN00_001571"
     CDS             29550..30422
                     /locus_tag="KRN00_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBH1827438.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKSHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            30423..30866
                     /locus_tag="KRN00_001572"
     CDS             30423..30866
                     /locus_tag="KRN00_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827439.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSKNTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            30881..31465
                     /locus_tag="KRN00_001573"
     CDS             30881..31465
                     /locus_tag="KRN00_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827440.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            31718..32755
                     /locus_tag="KRN00_001574"
     CDS             31718..32755
                     /locus_tag="KRN00_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH1827441.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            32836..33201
                     /locus_tag="KRN00_001575"
     CDS             32836..33201
                     /locus_tag="KRN00_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827442.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            33206..33523
                     /locus_tag="KRN00_001576"
     CDS             33206..33523
                     /locus_tag="KRN00_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827443.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            33571..35175
                     /locus_tag="KRN00_001577"
     CDS             33571..35175
                     /locus_tag="KRN00_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827444.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            35299..36927
                     /locus_tag="KRN00_001578"
     CDS             35299..36927
                     /locus_tag="KRN00_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBH1827445.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            37192..38541
                     /locus_tag="KRN00_001579"
     CDS             37192..38541
                     /locus_tag="KRN00_001579"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBH1827446.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            38697..39776
                     /locus_tag="KRN00_001580"
     CDS             38697..39776
                     /locus_tag="KRN00_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1827447.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
BASE COUNT        16395 a         4254 c         7178 g        12071 t
ORIGIN      
        1 agattaatat tttttgtaaa tgacaaaatt gtaaggtatt ttgttataaa atattaagat
       61 tcatagtgta tactaataat atagtattta gtataaatct tgagcaaagg atggttattt
      121 ctaatggata gactaaagaa tattagaaag agtttactac agtatacatt tttatttttg
      181 ttaataggta taacaattta cctagtgttt aaaacattgg atattaaaat gctatcaaat
      241 gttatggtta tggtagataa gaagttttta ttcataggtg ctttggcaat aatgtgtcac
      301 ataatgcttg aaggagtagt aatgaagata attatagaaa gcactcacaa agttaatatt
      361 agatttattg gttttaagct agccattatg ggattttatt ataatttaat aactcctttt
      421 gcttcaggaa gccaaccagt acagatatat gtacttaaaa aatgtaaaat gccacttagt
      481 aaggcaagtg cagttgttac caataagtct attatcttcc aaatagtagt tactttttat
      541 tgtacaatac ttgttttaat gaattttgct atgttagaaa aacaaatgaa aatgattatg
      601 cctctagtgt ttctagggat agccattaat tcatttgtct taattatgat aatattagtt
      661 attttaaatc ctaaaaaaat aaaatatttt atgagaatta ctataaagca tttatcaaaa
      721 attaagtttt taaaattttt agataataag attgaatcca tagaaagttt tatagatgat
      781 tatagtaaag caataaattt ttttgcaaag aataaaaagg tattaatttc aactataata
      841 gtaactttta ttcaattaag tgcttacttt agtgtttcat tttggatata taaagcattt
      901 aatttacaag gttatagcta tatttatata ctgacattac aagcattttt atatatggca
      961 atatctccaa taccaacacc tgggaatgta ggagctaatg aattagcctt tttcactata
     1021 ttcaaatcag tattccctca acctttgatg ggatatgcag tatttttata tggtggattt
     1081 atgtactatt tgattctgat tggaagtgga atatttactg taattactca ctatagaatg
     1141 aaaaatagaa ttggcagaaa tattgtttta agtgaaaact aaataagttt aaagaatata
     1201 tattgagtat attaaaaaat atgtcataag aactagaata ttttaattaa atggttgaaa
     1261 tataaagatt attatgacat attttttttg aaatttaaga ggaattgtga gaaaattgtt
     1321 gaatttaata gatagtattg caaaatattt atgattttgc atattataaa aacactcatt
     1381 atctttaaga taaattttac ttatcagggg ataaatctaa ggggggaatt gtatggagaa
     1441 aaaaatttta acagtttgtc catactgtgg agctggatgc caattatatc tagtagtaaa
     1501 agataataag atattaagag ctgaaccggc taatggtaga acaaatcaag aaagtttgtg
     1561 tttaaaaggt cgttatggat gggattttct aaatgaccct aaaattctaa cacctaggct
     1621 aaaaaagcca atgataagaa aacaaggtgt actagaagag gttgaatggg atgaggctat
     1681 aaactataca gcttcaagac taaatgaaat taaagaaaaa tatggacctg attctattat
     1741 gggaacaggt tctgcaagag gacctggtaa tgaagcaaac tatataatgc aaaaatttat
     1801 gagagctaca ataggaacta ataatgttga ccattgtgct cgtgtctgac atgcaccatc
     1861 tgtagccggt ctggcttact cattaggtag tggtgcaatg tctaattcta taccagagat
     1921 agaaaatgca gatgttttat ttatatttgg atataatgga gcagattcac atccaatagt
     1981 ggcaaataga atagtaaaag ctaaaaaaaa tggtgctaaa ttaattgtta ctgaccctag
     2041 agtaactgaa tctgcaagaa ttgctgatat acatctacct ataaaaggtg gaacaaacat
     2101 ggttttagta aatgcttttg gaaatgtatt aatagaagaa ggtctttaca ataaagaatt
     2161 tgttcaaaat catacacaag gatttgatga gtataaagaa attgttaaac catatacagc
     2221 taaatatgct gaaaagatta caggaatccc agaagagctt ataagaaaag ctatgagaga
     2281 atatgcaaaa ggtaaaaaag ctatgatact ttatggaatg ggtgtctgtc aatttggtca
     2341 agctgttgat gtagttaagg gacttgcatc aattgctcta cttacaggta attttggtag
     2401 agaaagcgtt ggaataggac ctgtacgtgg acaaaataat gttcaaggag cttgtgatat
     2461 gggagctctt cctaatgtat atcctggcta tcaaaatgta actgatgata agataagaga
     2521 aaagtttgaa aaagcttggg gggtaaaatt atctcctaat aatggttata gtttaactca
     2581 agttccagac ttagtactag aagagaaaaa gcttaaagct tattatatat ttggagaaga
     2641 cccagtgcaa agtgacccag atgcatcaga agttagagaa gcattagatg aattggaatt
     2701 tgtcattgtt caagatatat ttatgaataa gacagcactt cacgctgatg ttatacttcc
     2761 agctacttct tggggagaac atgagggagt atatacatgt gcagatagag gattccaatt
     2821 gatgagaaaa gctatagagc cacaaggaga tgtaaaacca gactggcaaa ttataagcga
     2881 aatttctaca gcaatgggat atcctatgaa ttataaaaat actaaggaaa tatgggacga
     2941 acttagacaa ttatgtccaa gtttcttagg tgctacttat gaaaagatag aaactcaagg
     3001 atgcgttcaa tggccttgta agagtgaaag tatggaagat aaagggacta tgtatctgta
     3061 tgaaggtcaa aagttttcta ctcctaatgg taaaggtaat ttgttcgctg ctgaatggag
     3121 accccctatg gaagttgaag atgatgaata cccatttagt ttatgtactg taagagaagt
     3181 tggacactat tcagtaagaa caatgactgg taattgtaga acacttagtt cattagaaga
     3241 tgaaccagga cgtgttcaaa taaattctaa tgatgctgaa aaattaggaa ttgaagatga
     3301 tgaattagtt agaattagtt caagaagagg aagtgtaata acaagagcaa cagttactga
     3361 tagagttaag gaaggtgcaa catatatgac ttatcagtgg tgggttggag cttgcaatga
     3421 acttacaata gcaaatttag accctatatc taaaacacca gagtataaat attgtgctgt
     3481 taaacttgaa aaacttgaag accaagaatt agcagaaaaa tgtgtaagag aagagtatca
     3541 aagtttgaaa gacaaaatga cagctacaaa tatctaatga tttattagat ttaagattta
     3601 taaaaggcag aaaggctaat attttatgaa caatatatac tcaaaaacta aattacaaga
     3661 aaatagtaag gataaagttt ttgaaaatag ttatagtcta gtggactaca aatatttaaa
     3721 ttcttttaat gtagaagtaa gcaaaataaa tgaacatgaa gtatcaatag ataatgaaga
     3781 aataattgca gaatatccac ttagttttat tttaaatgat aaatatgtaa atacattttt
     3841 atgtacccca tataatttag aggaacttat agtaggattc ttgaaaacaa aaggatacat
     3901 agaaaacaaa aaaagcttat taaaatttga gataaatgag agtgaacgtt ttgcaaaagt
     3961 aactattcaa gagaaacaaa aaaatcaaga tgagcaaatt atatttttaa atttactaga
     4021 ctatataaca tgcgctcctg taaagagcaa tataaaaata aattatgata cgatttacag
     4081 tataatggat aaaaatttaa attcatcaga attatttaaa aatactggtg gggtacatag
     4141 cgtatctgta tttaattttg ataaaaaaat agtcacttgt gaagatgtag caaggcataa
     4201 tgcaatggat aaggctattg gattttgtgt tttaaatgac ataacattaa aagataaaat
     4261 tgtggctgta agtggaagaa tatcattgga aatgatatta aaagcagcta tgactcaaat
     4321 tcctattgta gtatcaaaat cagcaccgac taatttatca atagagcttt ctaaaaaatt
     4381 aaatataaca cttattggat ttgtaagagg aagacggatg aatatttatg caaatccaca
     4441 gagagttatt aaaaagtgag aatgaatata tgtgtactaa aaaagaaaag caaagatatt
     4501 caaagtgtga aatctgtgga gtattaattg atgatactga taaggtgtat aataacacat
     4561 acaatttgtg caaaaaatgt aaacgaaata taagtactga gaaaatagtg aaatatataa
     4621 atatatatga tgaaagtaag tagacatatg atgaaaataa ctagagggtt ggaaatatac
     4681 aaattgaaag gtgggataat atgaaaaata aaataggctc ttttgtaata gcagacccaa
     4741 acaaatgtac aggttgtaga gcttgtgaag tagcttgttt tacaatgcat aatcagcata
     4801 ataatgtggg ttatacagtt ggaacagttg atatacctgt tatacctaga ctttacttag
     4861 taaaaggtga caatttctgt atgccaatac agtgtagaca ttgtgaagat gctccttgtt
     4921 taaactcatg tccacaaaaa gctatagtta aagaaaacaa tattatgtct gtaaatgaag
     4981 aaaagtgtat aggatgtaaa acttgtctgc tagcatgtcc ttttggagct atagacttac
     5041 ttccacaata tgaagatggt aaagaagtag aacaagtaat tttagatgaa aataagaaga
     5101 tagcttataa atgtgactta tgtaaagaca atgaaaaaat agcttgtata agtgcatgtc
     5161 ctcaggaagc attaaaactt gttactccaa tagatgacaa aaaagctaag aatatacaag
     5221 ctgcacttag tttattgtta acaaataaat aaaggataca ggggtaggtg acgtttatga
     5281 taataaatat agataaggat ttatgtactg gatgtagaga atgttcaaag gtctgtccag
     5341 taaatgctat tgaaggtgaa gagggaaagc cacaagagat aaatttagat agatgtgtta
     5401 tgtgcggtca atgtgttcaa acttgtaaat cttatgcctc agttatagat gaaggatttg
     5461 agtttttaca agagaaaaaa caagaaagag agataccaga gtctataaat gaacctatat
     5521 ttgcagcata caatgtatgt gatatagata aggtgaagaa agctttaagt gacccaaatg
     5581 tattcactat ggtccaatgt gcaccagcag ttagagttgc tttaggagaa gatttcggat
     5641 attatttagg atacttaggt gctgggaaaa tggcagcagc acttagagct ttaaattttg
     5701 atagagtcta cgatactaat tttgcagcag atttaactat aatggaagaa ggtagtgaat
     5761 taattaaaag agtgacagaa ggtggaactc ttccaatgtt tacatcttgt tgtccagctt
     5821 gggtaaaatt catggaaaaa aattatccta aattaactaa tcatttatct tcttgtaaat
     5881 cacctcagca gatgggtggt gcaatattta aaacttatgg tgcagagata aataatgtag
     5941 atgcatcaaa gatatttagt gtttctataa tgccatgtac atgtaaaaaa tatgaatgtg
     6001 atagagaaga aatggattct agtggatata gagatgtaga tgtagtatta actactagag
     6061 aactagctta tttaataaaa gacatgggaa ttgattttaa aaatttaaga gaagaaaaat
     6121 ttgatagtcc tttaggtagt tatagtggag ctggaactat ctttggtgtt actggtgggg
     6181 ttatggaagc tgctataaga acaggatatg agcttataac tggagaaagt attcctgatg
     6241 tagaagtaaa acaagtaaga ggagaaaatg gttttagaaa gtcaactatt aaaataggag
     6301 acttagactt aagagttgga gtagtaagtg gattaaaaaa tgtaatacca gtgcttgaag
     6361 acttggaaaa aggaaaatta gatgtagatt ttattgaagt tatgacttgt cctgttgggt
     6421 gtgtaagtgg tggaggtcaa ccaaaaattt tactagaaga atataaggaa ttggcttatg
     6481 aaaatagaac aaaagcaaca tacgtgcatg atgaacattt agcaattaga aaatctcatg
     6541 agaatcctga tattaaaaaa ctgtatgatg aatatctggt agaaccatta ggagaaaaat
     6601 ctcatcatct attacacact acatattgta taggaaagga agtggctaag tgatgaacta
     6661 ttttgttata gcagaccctg ataaatgcat aggatgtaga acttgtatga taggatgtgt
     6721 agttgcacat tcagatgaag atatttttta ccaaaatcca gatgaaataa attttaatcc
     6781 aaaactttct gtcataaaga caaaagaagt aagtgctcca atacagtgta gacattgtga
     6841 agatgctcct tgtgcaaagg catgtccaaa tggtggtata gttagggttg gtaacacaat
     6901 aaaaatcaat gaagaaaatt gtataggatg taagacttgt atgttagcat gtcctatagg
     6961 tgcaatagac atagttacat taaaagatgt agatgaagga aagctttgct ttagagaaag
     7021 aatgacagca aataagtgtg atttttgtat agaatcgcca gaagggcctg catgtgtaaa
     7081 tgtttgtcca actaaggcat ttactatagt taaggatgag gatatagata gtaaagttaa
     7141 aaataagaga aaattagcta tattgtaata taaaaaagat ggagttttat ttatgattaa
     7201 aagctccatc ttttttatta taatatttat atatctaaaa atcaattatt gcattagttt
     7261 atctaatctt tctttattca attttttcat tcctatagaa gttataataa gtaaagtata
     7321 ggcaattata actgataaaa ttataataga ccaagaaaat ctgtatccaa aattatcaac
     7381 taacaatcca aataatgttg aacctaatgc aaatcccact gcaaaaatta attgtacgat
     7441 tccatatatg ctaccaaact ccttttgacc aaagaaagag ccagttaaat aagcaggacc
     7501 aatcatataa gcaaatacag aaagaccttt caaaatggca aatacaaatg caaaagtaga
     7561 agatttatct accaatagta atgataaagt tgctataaga accaatacaa aagatataat
     7621 aagtggcttt gtttgaccga atttatcaaa caataatcct ccaaataaat taccaatgag
     7681 agcaaataaa gcaaatgtgg agcctactgt tcctattaga ataggattta gataatttct
     7741 aagataagtt ggatattgta cagataatga tgaaacatat ataccaacaa atataaatcc
     7801 aatagtcata atccaaaaat atttaatttt tttagcttct tttaatgtat aaccccatac
     7861 tgaaggagaa attttatcag atgctttctc ttttttacct ttagatttta ccttttcatt
     7921 aatatcttta ggcatcctga gtataaataa tattacaggt ataccaacta ttaatgctat
     7981 aattccaaat attagataag aacgactgta tccttgagtt gctaataagc gaactgcaag
     8041 tggttgtaga aatatactac caatagaacc accagcaaaa gcaaagccca aagcttttcc
     8101 tttgctttct tcatcaaacc aagcacttat taaaacaggt attcctatag cagatataat
     8161 tgtagcgcca atttgaacaa tacatgatac agtgtaaaat tgccatagtt cagtacatat
     8221 agaaaaagta gcaaaagcaa tactagaaat tatacaacct aataaatata gtatcttaat
     8281 attgacttta gaaaataata cacctataaa aggtgatgca attgctgagg caatagtacc
     8341 aatagtgaat attagagaaa aagaagctaa actaaagcct tctccttcta caacataact
     8401 tataaattga ggctgtatac ttgctacaat actaaatgga acagcttgta ttaacataca
     8461 accaagtact ataacccaag catttgaaaa gtttttaatg ctaaatttat tgtttagtaa
     8521 tgtattcatg gtatctctcc tttaggttat gatttgtaga tattaatcta attattctaa
     8581 ttttatatat tagttttgga tagcctaact atttaaatat aatttgggta ttaatataaa
     8641 aattaactat aaaaattgat tattttaaat gtatggggta aattaaagta tataaataaa
     8701 tgaaaggatg gataaaatgt catttgaaaa aataaataat aataacctag ataaaataca
     8761 caacaggaag tgtattatgc ttgtaaactt taataaaaaa gaattatcat taattaaaaa
     8821 cgtaagtaac tttgctggaa taagagacca tatcatctta agtgataaaa atggagagaa
     8881 tataataaga gacattttag atggaaatat atcaaatgaa tgtgaaaatg ggattaagag
     8941 taagtctgta atatttaata acactccaag cacacaagta aatgcatttt tagaagggct
     9001 aaaaaaagtg agaataaata gaccttttac agctatggta acagagacat ctattgattg
     9061 gacattgaat aatttaatag aaaatttagt tcaagaacgt aatgctatgt ctttaggaaa
     9121 aacaattgaa cataagtaaa tttaagatat cttatagtaa ttttaactaa tgtacattga
     9181 gtatcatatt atattttaga atataaaatt ttaaatgtgg gtagatggag gagatttgag
     9241 atgaaagttt tatttacaat aaattatgga aaagaaaaat ttgataaaat aagagaatta
     9301 ggctatgatg tcatacatta ctctgaagat agtattgaaa ataatgagga tgtaaataca
     9361 gcagatgtac tagttacata caatccattt gagagattag atatttctaa gatgaaaaat
     9421 ttacaatata tacagacaac tagtgtaggt atagaccaac ttccaaaaga agaggtattg
     9481 aagagaaata ttaagatagc taataataga ggcggatata gtgtacctat tggtgaaagt
     9541 attgtattgt atattttaga aatatataaa aatagtgcaa aattttttaa acaacaacaa
     9601 aataaagaat ggaagatgga tttttctgta tcagaattgt atggacaaag agttggattt
     9661 ttaggaacag gtactatatc ttcagaagca gcaaaaagat taaaagcttt tggtgtagaa
     9721 atatggggtg tcaatactga tggaagtagt aaaaaatact ttgataagtg ttttgctact
     9781 gaggatatga atattgtatt tgaagaatgt gatatagtag ttgtagcaat gccttctaca
     9841 aaaagtacag atggaatagt aaacaaagat atgtttaaac ttatgaaaga tggttctgta
     9901 tttataaatg taggtagagg aaatacagtt aatcagaaag atttagaaga atgtgtagag
     9961 aaatttagag gggtagcatt agacgtattt gaaagtgaac ctttaaacaa ggacaataag
    10021 ttgtgggagt gcgaaaatgt catagtaact cctcataatt cttgggtgtc agataaaaac
    10081 aaagagagaa catttaatat ggtttataat aatttgaaat actatataat ggagaataaa
    10141 cctgtagata atgttgtaga catatcaaga ggctattaaa aataaaaaat tttgataaaa
    10201 ataaaaactc ttattagtcg tattaaagat actaataaga gttttttttg taataaattt
    10261 aaagccaaaa aagtgatata ctaaaaaata tataaatagg agataattaa ttatagggaa
    10321 atttcaaaat aatttaattt taaaaatatg aagaggtgca aaaagtgagc gtaaaagatg
    10381 aaattaataa acttatagag acaataaact accataatga aaggtattat aatcaagata
    10441 gcccagaaat atcagattat gaatacgata agttaatgaa ggagttaatt tctttagaag
    10501 aagaacatcc agaactaaag agaattgatt ctccaacaaa tagggtagga ggtaagccat
    10561 tagataagtt caatcaaatt gtacataaaa ctcctatgtt gagtttatca aatgcttttt
    10621 cagagcaaga tttgagagat tttgataaga gagttcaaga atatgtggga gaaaatgttg
    10681 aatatgttgt tgaatttaaa atagatggtc tttctgtagg tctaacttat aacaatggag
    10741 agtttgaaaa aggagcaact agaggagatg gagttgtagg agaagatatt tctcaaaact
    10801 taatgacaat aaaaagcata cctcttaaga taaatgataa aaaagaacta atagttagag
    10861 gagaagtata tatatcaaaa gataatttta gaaaagtaaa tgaacaacaa gaagaacaag
    10921 aacagccatt atttgctaat ccaaggaatc ttgcagctgg ttcattgaga caattagacc
    10981 caaaactaac agcaaagaga ccattagata tatttgtatt taatatggaa aatatagaag
    11041 aatacgattt agaaagtcac agtgaatcac tagagtactt agaaaaacta ggattttcag
    11101 taagtcagag ttacaaagtt tgtaaaagta tagatgaagt tattgagcat attgaatact
    11161 ggacagataa caggggtaat ttagactacg aaatagatgg tatggtaata aaagtaaaca
    11221 atataaaaca aagagacgaa atgggatata cagccaaaag tcctagatgg gcaattgcat
    11281 ataaattccc agcagaaaag aagaaaacta aaatagtaga tataatagta gaagttggga
    11341 gaactggtac aataacacct tcagcaattc ttgaaccagt cagacttgca ggtactactg
    11401 taagtagagc tacacttcac aatgaagatt atataagaga aaaagatata aaaataaatg
    11461 atacagtatt agttcaaaaa gcaggggaca taatacctca agttttagaa gttataaaag
    11521 aagaacgtac tggagatgaa atagatttta aaatgccaga aaagtgtcca gtttgttcag
    11581 agccaacaat aagattagaa ggagaagctg ctgtaaaatg tatcaatatg tcttgcccag
    11641 cccaaataag aaggggaatt atacactttg tgtcaaggga tgcaatgaat atagatggat
    11701 tgggagaatc tataattaca ctgctattaa atgaaaaaat tattcaagat gtatctgatt
    11761 tatattatat aaaaaaggaa gatgtagtcg acctagagag aatgggcgaa aaatctgctg
    11821 acaatttaat aaattcaatt gaaaaatcaa aagaaaatga tttatggaga cttataaatg
    11881 gattaggtat taaatttata ggagttaaag cagctaagat acttgcatat aactttaagg
    11941 atttagatga agtaatttct gcaactagtg agcaactaga agaattagag gaatttggaa
    12001 gtataatggc aaacagcgtt gtcgagtttt ttaaggaaga caaaaatatg aacgttataa
    12061 acaagttaaa aaatgtagga gtaaatacaa aatcattgga taatacaggt gaaaaagtag
    12121 aaaaaatatt tgaagggatg aaaatcgtat tgactggtac acttcctaca ttaaaaagaa
    12181 atgatgcaaa agaaatgata gaaaaaagag gtggaaaagc tacatctagt gttagtaaat
    12241 cgacaacatt tgttttggca ggtgaagaag ctggttctaa acttactaaa gcaaatgatt
    12301 taggaattaa agttatagat gaagagagat ttttagaatt attaaagtta tcatcgaaag
    12361 atgaagtaaa agctgtatta gagagttaaa aagtcgctta atttagtaga aaactactat
    12421 aattaatgat agaatagttc agtaagctaa taagattacg aaaaatgaca ataattaata
    12481 tttgacaaaa ttaaaaatta taaaaataaa tttataaaaa ataaaaaata tgagaaagga
    12541 tataaaaaat gaccagaagt tatgatagaa gtaatgaaca gataagacct gtaaagataa
    12601 ctagagatta tacaaagtat gcagaaggtt ctgttcttat agaaatggga gagacaaagg
    12661 ttatatgcac tgcatcagtg gaagaaaaag ttcctccttt tttaagaaat agtggtactg
    12721 gatggataaa tgctgaatat tctatgctac caagagcaac acaacaaaga aagataagag
    12781 atgcatctag gggaaaaatt gatggaagaa cacaagaaat acagaggtta ataggaagag
    12841 caataaggtc tgttgtagac ttgaataaat taggagaaag aactatttgg gtagattgtg
    12901 atgtgattca ggcagatggt ggaactagaa ctgcatctat aacaggggca tttgtagcag
    12961 ttgcagaagc aatatataaa ttatataaag caaagacaat aaaagagatg ccaataacaa
    13021 attttgtgtc tgcaattagt gttggtattg taaatggaat acacatgcta gatttatgtt
    13081 atgaagaaga ttctaaagca caggtagata tgaatataat aatgactgat aagtgtgagt
    13141 ttgtagaagt acaggggaca ggagaagaga aacctttttc gagagcagat ttaaatttat
    13201 tgttagagtt aggtgaaaaa gggaataaag aattaataag gcttcaaaga gaagctttag
    13261 gtgaaatatc agatgagata ttgggtatgg attatggtaa tgaagtagtg attgctacta
    13321 ataatgttca taagctagaa gaaataggtg aaatcttaaa agattttgaa tataaagtgt
    13381 actctttaaa agatgttgat ttagcaggta tagagatagt agaagatgga aaaacatttg
    13441 agcataatgc gttgataaaa gctagaacaa tagcaaaaaa gactaaactt atagcaatat
    13501 cagatgattc tggcttagaa gtagatgctt taggcaaaaa acctggtgtt tattcagcta
    13561 gatatgcagg agaacatgca acagatgaag aaaatagaaa aaaactgtta aaagctatgc
    13621 aaaatgtacc aatgagcaaa agaaatgcaa gattcgtctc tgcaatagca gtagtttttc
    13681 ctgatggaaa agaatttgta gtaagaggaa tttgtgaagg aatgatagga tttgaagaaa
    13741 aaggtaaaaa tggttttgga tatgatagct tatttatagt aaaaggatat gataagactt
    13801 ttggtgaaat acctagtgtt ataaaaaatt caatcagtca tagagcaaac gcactaaaac
    13861 ttatgaaaca agagtttata aaaagggtag tgaagtaatg aaaataggca tagtaagcga
    13921 cacacatatg atgattaaaa atatggaaaa aacaatacca tatttgaaag aatgtgacct
    13981 aataattcat gcaggagata actttactga ttcaagatat attcatagca tgactaatgt
    14041 aggtattatt gcagttaaag gtaattgtga ctttgatgct gttgaggaag aagttgtctt
    14101 tgaagtggca aataaaacca tattcttatg ccatggagat aagtatggtg taaaatatgg
    14161 aactaatatg ttagaaaaaa aggcaactga agttgatgct gatatagtta tatttggcca
    14221 tacccatacc ccatttagag aaattaaaga tggtgtactt tacataaatc ctggaagcac
    14281 ttcacttcca agaggagtat cgtataaaag ttttgtcatt atggatatag aagaagatga
    14341 cataaaaatt gaagaaatac gcatataaag gtgtatttat ctaaaaaaat ggcaaaaaac
    14401 gctcaaaaaa ttaaatttta tcaaataagt acaacgatat taatggaaca cttgtaaata
    14461 aaaaaactta tgtgatataa ttaagtggtt gaattataaa tagaatgaat tataataccg
    14521 ttatcgggta ttacataaat atcactagga ggattagaag gatgaaagca gaactaatta
    14581 aaaaagaggg taataaagtt actttaaaaa taacagtaga taacaataaa tttgaagcag
    14641 cagtaaataa ggcttataat aaaagcagaa ataaatacaa tatacctgga tttagaaaag
    14701 gtaaagctcc aagaattgtt atagagactc aatatggaaa aggtatattc tacaatgatg
    14761 ctatagaaat attattccca gaagtttatc cagaagctat caaggaatta gacatagacc
    14821 caatagacaa tccagattta gatatagaag aaataagtaa agacaatggg ttggttatgg
    14881 ttcttaatgt agaagttaaa ccagagtttg aattaggaaa ctacaagggt atagaaatag
    14941 ctaaggttga gaatactgta agtgacgaaa atgttgatgc taaactacaa gaaatggttg
    15001 aaaaaaatgc cagattagta agtgtagaag acaaagcttt agaagatgga gatacagcta
    15061 taatagactt cgaaggtttt gaaaatggtg tagcttttga tggtggtaaa ggtgaaaatt
    15121 ataacttagt tataggttca aacacattta taccaggatt tgaagaacaa ttagtaggta
    15181 aaaaagctgg tgaagaagta gaagttaatg ttactttccc agaagaatat cactcacaag
    15241 atttagctgg aaaaccagtt gtatttaatg taaaaataaa tgatgtaaaa gtaaaagaat
    15301 tatctgcact tgatgatgaa tttgctaaag atactagtga atttgattct ttagatgaat
    15361 taaaagcaga tgtaagagct aagttagaag aagaagctaa aaatagagca gatgcagaaa
    15421 ctagaaattc agtagtagaa aaagttgctg aaaatacaga aatagaaata ccagaagtta
    15481 tgatacaaca tcaaatagat aatatgttaa atgaacttaa ctaccaatta caatatcaag
    15541 gatttggatt acaacaatta ctagagatga ctggtagaac tatggaagaa ttaagagaag
    15601 agagaaaaga agatgctaaa aaattagtta agtcttcttt agtattagaa gcaataacta
    15661 aagctgaagg aattgaagca acagaagaag aatttaaggc tgagttagaa aaaatggctt
    15721 ctgcttacaa tatggaagta gaaaaaatag aagcttcttt aagagatgct gacaaagaag
    15781 atataaaagg tcaaataaaa ataagaaaaa caatagattt attagttgat aatgcaacaa
    15841 tagcttaata aaataaacgc taactaatat agttgacgtt atgaaatgtt tagtatataa
    15901 tgatgtgcaa atataattta gttaaatgcg tataataatt tacagtagct taaaaaaagc
    15961 tactgtaaat tatatagaat aaagggggta tgaaaccatg gcattagtac ctgtagttgt
    16021 tgaacaaaca ggaagaggag aaagatctta tgatattttt tctagactat taaaagacag
    16081 aataatcttc ttaggagatc aagttaacga tgccacagca gggcttatag tagcacagct
    16141 attattttta gaagctgaag acccagacaa agatatacat ttatatataa attctccagg
    16201 aggaagtata acttctggaa tggctatata tgatactatg caatacatca aaccagatgt
    16261 aagtactata tgtataggta tggctgcttc tatgggagca ttcttgttgg cagcaggagc
    16321 aaaaggaaaa agactagcac taccaaatag tgaaataatg atacatcaac cattaggtgg
    16381 agctcaaggt caagcaacag atatagaaat tcatgcaaag agaattttaa aaataaaaga
    16441 aactttaaat gagatattat ctgaaagaac tggtcagcca ttagaaaaaa ttaaaatgga
    16501 tactgaacgt gataacttca tgagtgcact agaagccaaa gaatatggtt taatagatga
    16561 agtatttaca aagagaccgt agatagagag aggtgttaat atgtctaaat atgaagaaaa
    16621 acgacaatta aagtgttcat tctgcggtaa aaatcaagat caagtaagaa gattaattgc
    16681 aggtccaaat gtatatattt gtgacgagtg tgttgaactt tgtgacgaaa ttattcaaga
    16741 agagatagaa gatactatag atgaggatac tacatcttta ccaaaaccaa aggaaatgat
    16801 ggagattcta aatgattatg taataggtca agaaaaagct aaaaaagctt tatcagttgc
    16861 ggtttataat cattataaga gaatatacag taaaaaatct agtagtaagg atatagaaat
    16921 tcaaaagagt aatatacttt tattaggacc tacaggttct ggaaagacat tacttgctca
    16981 aactctagca agaactctaa atgtaccttt tgcaatggca gatgctacat cattgactga
    17041 agctggatat gttggagaag acgttgaaaa tatactttta aaacttattc aagctgctga
    17101 ttttgatata gaaaaagctg aaagaggtat aatatatata gatgagatag ataagattgc
    17161 aagaaaatct gaaaacccat ctataactag agatgttagt ggtgaaggtg ttcaacaagc
    17221 acttctaaaa atattagaag gtactgttgc aaatgttcca ccacaaggag gaagaaaaca
    17281 tcctcatcaa gaatttttaa agatagatac tactaatgta ttatttatat taggtggagc
    17341 ttttgatgga ttagagaaga taattcaaaa acgtggtgga gataaaacac taggttttgg
    17401 agctaaaata gaaagtaaaa aagaattaga tttagggaag ctatatgaaa aagtacttcc
    17461 agaggattta ttaaaatatg gtataatacc agagtttata ggaagaatac cagttttagc
    17521 tactttagag ttgttggatg aagatgcatt aatgcagata ttacaggaac ctaaaaatgc
    17581 tctagtaaaa cagtataaaa agttattgga gttagatgat gttgagctag aatttgaaga
    17641 aggtgctctt cgtgcaatcg ctaaaaaggc catagaaaga aatacaggag ctagaggact
    17701 tagaagtata gttgaaagcg taatgatgga aactatgttt gaagtaccat ctagagataa
    17761 tataaagaag gttatagtaa cagagaaatc tgtgaacgaa gactcagtaa atcctatcat
    17821 agtacttaag gatcaagagg aaagtgcata agatgatgaa aaggagcttt aaaagctcct
    17881 ttttttatgt taatatgcta aatataaaat aggtatcatt attataaaaa tgtgagtaat
    17941 atacctagaa taccaaagac gaatacaatt gcaatggaac caatttttcc tttatataaa
    18001 agataaaatg atgctataaa tgcaattatt ccatataagt cccaattaac ttctttggca
    18061 gatgaaaaag ctgctgataa tatgaatcct agagtaattg gtctaagaac tgtcaataag
    18121 ttttctacct ttttattatt tttaaattta gaaaataact ttgatataat agttagacct
    18181 attaatgcaa aaattgtaac accaatagtt gcagctagag aaccaaagaa gccagcagtc
    18241 ttaaatccta caaatgtagc actatttatt gctacaggac ctggtgtaga ttgtgatata
    18301 gcaagtaaat ccaaaaactc ttgattagtt ataaagtgat atttagatat aaattcttgc
    18361 tggataaatg gtagcatggc ataaccgcca ccaaaactaa atgcccctat tttaaggaat
    18421 attaagaaga gtagtattat ttctgacata gactatatac acctcctcca attattaaat
    18481 aaatagggct tatattgaat acaccaacag ataaaactgc tataattaat agtagtatgt
    18541 tagttttaga ctttggtagt ttcttgaaca tgctcgtaaa agaatacaat ataagagcta
    18601 ttacaacagg cgcaactcct ttaaaaaatc catctaaaat tttagatgat gaatttttaa
    18661 agtatagata cgataagact aagactatac aaaatgatgg taaagcagag cctaaggtac
    18721 atataagaac tcctggtata ccataaagtt tatatcctaa taatacagat atattaactg
    18781 ccagtactcc aggataactt tgagctatgg ataaataatc aataaattct tcctgctcta
    18841 aaagtttttg tttgtttaca agttcatctt gtataagagg aaccatagcg tatccaccac
    18901 caaatgtaaa cgcaccaatt tttaaaaagg ttaaaaacaa tttcaacata atagaaacct
    18961 ccaaaagata aataacatct aagtatacta atattaatat tatatcataa taaaaagata
    19021 atatagtatg atagtattct aagaatttat cattaatgtt gaaaattaac ttgttcaaat
    19081 atataatatt aaaagcaaag caattagact agaaaaggag taatgttgat ggaacaaaat
    19141 tatactaaaa tagatcatga attaccatta attcctctaa gaggattagc tatatttcca
    19201 tatatgatat taaattttga tataggtaga gagatatctc ttaaagcttt agaccaagct
    19261 atgatggatg aagaacttat atttttaact tctcagaaag aagcagaggt agatgagcca
    19321 ggagaagagg atttttatca tgtgggaaca atctgtaaag ttaagcaaat gataaaatta
    19381 ccaggagata cagttcgtgt tttggttgaa ggtgtatcaa ggggtagagt aaagaaaata
    19441 gaacaagaag atgggtattt cagagcagta atagaagaaa tagtatttga tagtgataat
    19501 ttggatagtg aaacagaagt tgaaattgaa gcatttgtaa gaaatgtatt tgatgccttt
    19561 gaagagtata taaatattgg aaatagggta tcaccagaaa tattaatatc tttagctgat
    19621 atagaagatg tagatagatt tatagatacg atagctgcaa acatatatct aaaatcaagc
    19681 caaaaacaag aaatattaga agaatttgat attagaaaaa gacttgaact tatttattct
    19741 atattattag aggaaataga tatattaaaa atagaaaaga aaataacttt aagagtaaaa
    19801 aaacagatga ataaggttca aaaagaatat tatcttagag aacaattaaa agctatacag
    19861 aaagaattag gtgaagaaga agatataaac tctgaagcag atgagtatag agaaaagctt
    19921 aaaaaaataa aagcacctaa gacaactaaa gagaaaatag aaaaagagat agataaattt
    19981 tcaaaaatat cttctatgtc tccagatgta tctgtaagta gaaactattt agatactata
    20041 ttctcattgc catggaataa agagacaaaa gataaattag atataactaa ggcaaaagat
    20101 atattagatg aagaccatta tggattagaa aaagttaagg agagaatact agagtatcta
    20161 gctataagaa ctcttgctaa gtcacttaaa gggcctataa tatgtctagt tggtcctcca
    20221 ggaacaggaa agacatctat agtaaaatca atcgccagag cattaaatag aaaatttgta
    20281 agaatatctt tgggtggagt tagagatgaa gcagaaataa gaggtcatag aagaacttat
    20341 gtaggttcaa ttccaggaag aataattaat ggggtaaaag aagcccaaac aaaaaatcct
    20401 gtattcttat ttgatgagat agataagatg gcagcagatt ataagggtga cccagcttca
    20461 gcaatgctag aagtattaga cccagagcaa aataaggatt ttgtggacca ttacttagaa
    20521 ataccttttg atttatcaaa aatactattt gttacaacag caaatagtct aggtaatata
    20581 ccaagaccat tattagatag aatggaagta atagaagtat ctggatatat agaagaagaa
    20641 aaattaaata tagcaaaaaa atacctactt ccaaaacaga ttaaagaaca tgctttaaaa
    20701 gaaaacttta taaaaataga tgatgaaact ttaagaagta taatcaacca ttatacaaga
    20761 gaagcaggtg taagaacact agaaagaact attggtaaga tttgtagaaa ggttgccaaa
    20821 aaatacgttg aagacccaac tcttgaagag gttgttataa ataagtctga cctagagaca
    20881 tatcttggaa aagacatgtt taagtatcaa cttgcagaag ttaaccctca aataggatta
    20941 gtaaatggtc ttgcgtggac agaagttggt ggagttacac ttgaagtaga agtaaacgta
    21001 cttaaaggta aaggagaaat tgtattaact ggaaaattag gagatgttat gaaggaatct
    21061 gcgaagacag gtatctctta tataaggtca atagtggaca agtttgatat agaccctgaa
    21121 ttttataaga cgaatgatat tcatatacac attccagaag gtgctgttcc aaaagatgga
    21181 ccatcagctg gtataactat ggctcttgca gtaatctcag cacttactaa aagacctgtg
    21241 cctggaaata tagcaatgac aggagagata actttaagag gtagagtctt agcagtagga
    21301 ggagttaaag aaaagttatt agcagctcat agagctggta taacaaaagt attaattcct
    21361 aaagaatgtg aagctgattt agatgaaata ccagaaaatg taaaagaaaa aatggagttt
    21421 gtgcttgtag aacatatgga tgaagtatta gaacaagctt tattaaagag tggtgaaaat
    21481 aatgaaaatt agaagttcag agataactat gagtgctgtg aataaatcac agtatccagc
    21541 agaaggaatc ccagagatag cattggctgg taggtcaaat gttggaaaat catcaataat
    21601 aaatacattg cttaacagaa gaaacttcgc tagaaccagt caaacaccag gaaaaactag
    21661 aactataaat ttttatctaa taaataatga attttatttt gtagaccttc caggctatgg
    21721 atatgcaaag atagctaagt ctgaaaaaga aaagtgggga ggtataatgg aacgatatct
    21781 agaaagtaga caagagttat gttctatatt cctacttgta gatattagac atgagcctac
    21841 agcagatgat aagcttatgt atgaatggat aaagcacttt ggatataact gtgtagttat
    21901 tgcaactaag gcagataaaa tatctagagg acaatatcaa aaacacataa gtataataag
    21961 aaaaaaattg caaatggaaa gtagtgaaaa agtaattcct gtttcttcac taaaaaagac
    22021 tggtgttgaa gagttatggg aagagattgt aaatcaatac aatcaacatg gatatgaaat
    22081 aacagtagat taaatttaaa atgttaaata ttgacataac atttatttga ataataaatg
    22141 taataatagt tagttttaat tatattaata ttaaagcaaa atataggatg ccttaaaata
    22201 gttttaatga actttttttg gcatccttat tgtttataaa caataaatat cagtaatttt
    22261 gctaaatact aataaatttt agtaaggtat gggaaaatta gtataaatta gttcaactaa
    22321 aaaattattg acttatgtag tcagcaataa atagcattta agaaatagat ttatctgttt
    22381 ttctcataaa gaaaacagtt agtataagcc ctataaaaca tactgatgct gcaatccaat
    22441 aagactgatt gctagctata acataggctg atgtgtgact tttaaacttt tgattgtatg
    22501 taagactttg tgcaaaaaaa ctactaaaaa atgctgttcc aagagcaaat gataaattac
    22561 gaatagttgc aagaaaactg cctccgtacc cctgtttttg aggaggaaca tctgctaaaa
    22621 tactactatt gtttggtgaa ctaaatgctc ctagcccaag tccaaaaata actaaacata
    22681 caattaaaag atacaatgga gaatctgctt ttaaaagtgc cattccaact agtgagatgg
    22741 tcataaatga aaaagatgct gttagaatgt tttttgcacc gtgtttatca gaaagtgaac
    22801 ctgcaatagg tgctataagt accataataa gtggatgtac agtcattaca taaccagcca
    22861 tcataggaga taaatttttt aattgttcta aataaaatgg aagtagaaaa gatactgcca
    22921 tttgaggaaa ataacaagct actccaatga tattgcctac agtaaagttt ctatttttaa
    22981 atagaggtag gtcaataaag ctttgttcaa attttacttc tcttaatgcc aacaataaga
    23041 agattataag cgctgttata cctaaataca atcttgtatt acccttctca ttcattgcaa
    23101 gtaatataag cgtagtgcaa gatgcgaaaa gtagaagacc tggaatatca aagctcttgt
    23161 tttgttcatc caaaacaggt ttaggtagaa atttaatgcc aagaaagact gctataatac
    23221 caataggtat attgataata aaaatagaag gccatccaaa atgttctaaa attatacctc
    23281 caattacagg accactcata tttcctatac caactacagc tccagtgatt cctatagctt
    23341 ttcctttttc atttgctgga aatgcattgg aaactatacc aagcccagta gccattaaaa
    23401 tacttgctcc aactgcctga aagattcttg aagaaattaa tgttgataaa ttgtttgaca
    23461 tactacacag aaaagaacct attgtaaata taaaaaatcc taatgtgtat agacgatttg
    23521 aacctacttt atcgccaagt tttccgaaaa ataacatagt agctgttaca acaagcatat
    23581 aagctgttac aacccactga atttgtgaca tgttaatttt aaagtcagca gcaattgtag
    23641 gatttgcgat atttagtata cttccatcaa gagtagacat aaatacacca atacagatga
    23701 taatcaatac tatccatttt tgtttcatga taacactcca atcttaatag attttataag
    23761 tacgatataa ttgtaaaata aacaacaaaa aaagcacctg tatattaggt accttgaatg
    23821 tgtctaattt catgaataaa tacggtagtt gaaggatttg tatagattac tcatgtaaaa
    23881 ttacataaag gtactcatat actattttct tctaccatcc agattttact gtcggctttg
    23941 gaatatgacc aaattatgcc ataaggctcg cgggctttta ccgccgatag ggaatttcac
    24001 ccgtttatga agaaaaacag atgtattttg taatattatt ttaacataaa attataatgg
    24061 aaacaattgg atttaagtaa tatccagctg tattacaata caaatatttc aatatggaca
    24121 cttaaattgt atttatagat agaataaggc acagtatgag aatctataat aattagataa
    24181 aattaacctg ttattagtat tagatggcaa gttttaaatt tgtcaaaatc agaaagctgt
    24241 aataaaattc ttataatatg aatatcttaa ttaagagata ttgtaaatta tgaggaggcg
    24301 ctaatatgga aggaaaggta aagaaggcat tcccgggtgg aaatacatca caaggctcat
    24361 attctttttt tgactatata attcctgaaa atgtaaaaag agttttttgt ttaaagggtg
    24421 gacctggagt aggaaaatcc tcacttatga aaaaaattta taaagagttt ttgcatagag
    24481 gatatgatat tgatttatat cattgtcctt ctgacccaag ttcgttggat ggtttagtta
    24541 taaagaaatt aggcgtggta cttatggatg caactgcccc acatactatg gacccaaagc
    24601 tacctggagc tttggatgag ataattaatt taggtgatta ctggaataca gaagaattag
    24661 aaaagaataa acaagaaata tcagtttatg ataaagatat tagtaattca tttaaaagag
    24721 catttaagtt tttaaaatca gcagaaccaa tctttagaga catagaagaa aaatattctg
    24781 attgtatgga ttatggcaaa gtaaatttgg tcacagaaga atttataaaa aggttatttg
    24841 atggagttaa aagcacagga aatctaaaaa gagaaaagca tttatttggt tcagctataa
    24901 ctcctgtagg gtgtttagat tatacagaaa acattttaaa agatgtaaag aaagtctatt
    24961 atttagatgg agaaatagga actgggaaaa ctacattatt aaacaaagta tataagaaag
    25021 ctattgaaaa aggtttaaat gtagaagttt atcattatcc acttattcca gagaaaattg
    25081 aaactgtact attaactgat ttagacatag gtataactat aagtacgact tttaaagaag
    25141 aagatacaat tgatttaaat cagtttttaa atagagaaaa actacttaaa tatgaagaag
    25201 atattaaatt tgatgaaaaa gttttagatg atttaatttg ttgggcagta ctaaatctta
    25261 agagagccaa gtctaaacat gatattatag aaagttacta tagtcctaat atgagatttg
    25321 atgaagtagg gaaattaaga gataaattaa ttaaaagaat tttaaaatat gaggaaaact
    25381 tataaacgta tatgtttaaa attaacgtta gtaataatat aatttttagt aaattggtgt
    25441 agctttgagg ctatgccatt ttactttttt tgctaaaaaa tgatattaat aatctccaaa
    25501 gtcattattt gtttttcata attattattt cctttcctaa tttatgtttt tttataatat
    25561 caaaacaatg tttattgaaa gtttatataa ttttaagaac atctaaaaat gcatacttga
    25621 tattggtaaa ttagtgatag gagttcaatg tatgatatta tatactaaag atgaatttta
    25681 atatataact ttgatataat aagcatatgt aaatgtttaa tatttaatta aagaaaatta
    25741 tcatataaaa ataaatttgt aaggagcaat acagtatgaa aaaacaatat gtgtttataa
    25801 tactagcaag tactatttta ggtatacttg ttggaaccat atttagagat tatagcaatg
    25861 aagaaacagt ttatacaagc aaagacaagt caataagaaa agaaataaaa atgacaagaa
    25921 aatctataaa agaattaacc aaagagaaag acaagttaga taaagaaatt aattcaatga
    25981 aacaaaatca aaaaaattct gcagaaatat cagaaataga aacacttaga gatagtctat
    26041 catattcaga tgtaaagggt agtgggataa tattaagtat agatgctata gatgaaaaaa
    26101 cagggaatat agctaatagt atagactata ataagattct tgtaaaagtt ataaatgaat
    26161 taaaagtaaa cggaggaaaa tacatagaaa taaatggtca aagaattaat caatattcag
    26221 aagttgtact tgcaggaagc catataaata taaatggagt tcctgtagca caaccatatg
    26281 aaataaagtg cattggagat aaggagaaac tatctaatta tgtagataaa ggtagtaaat
    26341 atttagatag catacaaacc aattatccaa tgaaaataag cataaaaact gaagaaaata
    26401 tctctatgaa aaaaatgaat atacctaata aattaaagta tataaagggt gattaagatt
    26461 atattagagg aaagcagttt gccaatgtta ataccagaaa aacttgcaaa aaaatataat
    26521 gtatttccag ttgagtttca agatgataat ttagttgtag aaatagaaga tgaggatatt
    26581 tatgctctac aggacttgag attagctaca ggtaaagaaa ttatattgaa gaaggagaaa
    26641 aaagaactta taagtgaaaa gattgaaaaa tattataata gctttgaact tgatgaggat
    26701 tatgcaaaaa aattatttga aaatctttta gaaaaagcta taaaagaaaa cgcaagtgat
    26761 atacatatag aaccatttaa agaacattta atagtgagaa tgagggtaga tggagaacta
    26821 aaggaagtat caaagttttt agttgatgtc tatccatcat tgtctacggt tataaaatta
    26881 aaggcatcaa tggatataac agaaaaaagg cttcctcagg atggtagggt ggatataaag
    26941 ttaggtggaa atttaattga cattagagtt tcatcaatac caactgtcta tggtgaaaaa
    27001 atagttttga ggatacttaa tagagatact tttttaaaag acaaattaga acttggtttt
    27061 tcagaggaag ctataaaatc tataaatcgt ataataaata aaagagcagg aatattatta
    27121 gtgacaggtc ctacaggtag tggaaagact acaacagtat attccttatt aaatgattta
    27181 aaaggaataa ataaaaatat tatgactata gaaaatcctg tagagtataa gatggatggc
    27241 ataagtcaga ttcaagtaaa ttcaaaagta gggttgagct ttgatgtagg tcttagagcg
    27301 atattaagac aagacccaga tataataatg gtcggagaaa taagagatgc agaaacagct
    27361 aagatagcag taagagcagc tataacaggt catttagtta taagtacttt acatactaat
    27421 gatgcagtat cttccatagc tagattacta gaaatgcaaa taccaccata tcttttaaat
    27481 gcctctctta taggtgttat atctcaaaag ttggttagaa aagtctgcaa tcattgtagc
    27541 catgagatta tgataaaaga taattttagt ggagatgtaa atactaaggt agctgtaggg
    27601 tgtgaaaaat gtaatgataa aggatacttt ggaagaacag caatttatga aatcttagaa
    27661 attaatgatg atataaagac atgtataaga aatatggagg attctagtac tattaaagat
    27721 gtggcacaaa ataatggaat gataacattt gaagatagtt gtaaaagact aataaatgaa
    27781 aaaataacga cattagaaga gtgtttagta gtaaatgaaa tgatttaact gaattgtata
    27841 gttaaacttc gtttggtcag ttgtctttat ttaatctatt ttaattaaga tgtttgagta
    27901 taaattatat ttaagtgaaa taaaattaaa tgtattaaat tagaaaatat taagtttatt
    27961 taattgtaat taatataatt tggaaggtat tatagtacat gagattatct aaaaatatat
    28021 tttataattt agaaaagttt tatttagtat taaatagaat cagtgataaa gaaattagag
    28081 taatttgcaa agagataggc atattgctgg aatctggatg tgaaattaca aaaatatttg
    28141 aaatcattga gagtcagtca agtaaaaaag taaagaactt gcttagtata gtatcaaatc
    28201 atattcaaaa aggtaactca atagcagaat catttcaaat aacaggtata ttttctaaat
    28261 tctttataag tatgataaaa gcaggagaaa ctagtggaaa cttagatata ataatgagtg
    28321 atttatctaa ttattatgat aaagaataca aattaaaaat gaaaataata actatttcaa
    28381 tatatccaat aatacttata atattatcta tcttatcaat gttgtttata ttcgtatttg
    28441 taatacctaa ttttcaggtg gtttttacca acaatggaat tgaaccacct ttaataacta
    28501 gagttttaat gggaatatct acagtggtta caaataactt agcttatata atatttagtt
    28561 ttatattgtt ttcaatagga agcatttatt tctttataac aaatgataat ataaaaaaat
    28621 tgattaattc gttaaaattc aaaatacctt ttataaaaaa aattaatcag ttagtagcta
    28681 caacaagatt ttcaagggca ttgtccgttt taattagcag tggaatacaa attgtggaag
    28741 ctatagacat gtcagctagt gttatagaca acgaatttat ttatgaaagg ttaaagattt
    28801 ctaataatta tataaaaaaa ggaaatagca taggtaaatc tttgaattta gcaaatattt
    28861 ttccaaaatt atttatttca atggcaaata caggagaaga aagtgggaaa ctagataaaa
    28921 gtctaaatgt aataaataaa ttttatgaaa atgaattaaa taacaaaata gagcaaataa
    28981 tgaaatttat agaacctatg ctaattgtat ttatgggatt aattattggt acttttattt
    29041 tagcaatggt tgttcctatg tttgatgcaa ttactaattt ttagagagaa aaataaattt
    29101 tattagatga aacttttgaa aaggagagaa tatttaattg ataaatttga taaataaaaa
    29161 acgaaaagga tttacacttg ttgaaatgat tgtagtagta actattttag gcgttatatc
    29221 tagtatagca ttagttaagt atagtaaggt tcaagaaagt gccaaattaa atgcagacta
    29281 tacgaatgct gctaatatag taaccgcagc tagcatggca attaatgatg atgaaaagac
    29341 aatagactct ctaagtgtag agacattgaa ggaaaaggga tacctaaata ctgttccagt
    29401 tcctcagagt acatcaggta aattcgaact tgtcataaat gatagcggaa cagatataag
    29461 cgtaaatata aattctaagc aattttatcc aaaataatat tttatattga ttgctataag
    29521 ttttaaaatt atttttattt aagaaggaga tggctataat taaaaaaatt ctaaacttag
    29581 aaataaatga tgattatata aggcttgtat ttttaagaaa aagtcataaa aaagttttta
    29641 tagataaatc aattataaaa gagattaact ttgatataaa aaatgatagt aattcgattg
    29701 agaagattaa atatatagaa gatgtagtta gatttgtaaa agaggagatt ggtaaatcaa
    29761 aaatattata taaaaattta tactttaaca ttcaaattca ggatatagtc attagaaatg
    29821 ttgaagttct aaatactaag aaaaaaagag acatattaag catgattgaa tttgaaataa
    29881 cacaatacat tccaataaac ataaataact attcaataaa atataaagtt ataaattcta
    29941 aaaatgataa attgaatata caagtaattc ttttcccaaa gagtattatt caattaatta
    30001 agaacatttc agaaaatcta aatatgaatc caaagactat aaatataaat tttgatatat
    30061 tacaaaagct tataaactta aatttaatag agaatttttc agaagaaggg gtatttatag
    30121 aatgtaaaaa aagtcagtta attataaata taacaaaaga taaaaaaata agagaaacat
    30181 acttgctatc aaaagaggga aaatcatatg agttcataaa aagattatta agggatttta
    30241 agtatgttta ttactatggt atagaaaatt gttttattga agaatacttt aaatatacag
    30301 ataaatctat tgaagtaaat ccattaagat taaaagataa agtaaaagta gaaaataatt
    30361 ttgatgcaga tttagaagac aataggataa attatataaa tagtatagga atgattattt
    30421 aagtgaaagt ggataaaaca ataaattttc ttaatggatt taaaaaaact aaaccatgta
    30481 ataaaatcta taaaataata atagtcttaa ttttaacgtg tattttattt aaatcattta
    30541 tgtatgtgaa atctataaat gaacttgaag attatataag tcaaaataag ctagtggata
    30601 aatcaaagaa cactttacca acaacagaca aaactagaga gaaattttct aaaataaaac
    30661 ttaatgaaat aaaaaaaata tatgaaacaa ttggaataaa tagtattact aaaatatcaa
    30721 tagataaaaa taagctagag atggaaggtg tgtgtagtga tttagatgtt ttaaacaatt
    30781 taaggaaaat aaagtacata aaatattatt acatagacag tattgtaaga gatggagaat
    30841 attatagatt tagaataaaa agttagatgg gtgattattt ttgagattaa ataatagaga
    30901 aaaaaatcta cttaaaatat tgttaatatt agttattata ttggcaagtg atatagcagt
    30961 aagttatttg gaagaaaacc taactagttt gaagaatgaa aagcaaaata taataaataa
    31021 aataaataat caagataatt atcaaataaa ggataataag catatagatg ataaatatat
    31081 agaaagtgtt gaatcaaata aaaatgaaga attaaaaaat aattttaata actcattttt
    31141 agataaaaaa acaaataaag atatagtgtt attagtagaa aatgaactga gagatattgt
    31201 gaatgtagaa tatattaatc aagaaagtag tttagataat cacaataaaa aacaagttaa
    31261 tttagaaata aaagttaatg gagaacttgc aaatgtgttg aaacttgaag gtgtaatgaa
    31321 gaagttaaga ctaaataata aacttgaaaa gatagaaatt aataaattaa aagtcaataa
    31381 ttttgatgtt caaaatattc caaatgaata taaacaagaa aaagacaata ttgttgaatg
    31441 taaaatgaca gttagagtca tataacaaaa aagaatagat aaagtaaaaa actattatca
    31501 attaataaaa ttttatagag gaattagttt tacgataatt catttctaca agagggattg
    31561 ttgatgattt tatcgaaatc ctaattaaag ttaatatatt gtaccaaaat ataagtgaat
    31621 ttaatagaat atttacttat actatagatt gattaataaa aaaatggtat aataacaaat
    31681 tgtactttaa tttaataata agggagtgga agtcatattg ttagggagaa atgagctatg
    31741 cccttgtgga agtggcaaaa aatacaagaa atgttgttta aataaagata ttgtttcaga
    31801 aagagcatgc agaaaaactg aactttcaca aaaacaatat acagatttat attcaaagtt
    31861 atatgattat tcaagacagg ataagtttaa agaagaatgt gaaaaagcta aagaaatgtt
    31921 ttatataatg caaaatgata gtgtaaatga aaaatttgaa agatttttta atacttattt
    31981 aatacaagac cacataatgg aaaataaaaa ggttatgaca gttggttttc ttgaagaaaa
    32041 tggtgcaaac ctaagtcaat cagaagtatc aatattaaaa agtatgtttg aatcatacgt
    32101 aagtatttat gaggtaaaag aagtttctgc tggaaaaata gtattaaagg actgtttaag
    32161 tggaaatgaa ctttgtacag aagatgtaaa acttctgaga agttttaaaa tcggaagttg
    32221 tatgatagct agaatagttg atattgaagg aactaacata ttgatagata taactataag
    32281 tatatcaaat gaggttaaag atataatttt aaaggatatt atgaatctat tcaatcaata
    32341 tcaagatgta tacaaagata tgaagtcgtt cttaatttat catacacata tactatacaa
    32401 gtatatacaa cagcttttag acccaagtat agctgaatat ttaaagagag aaagagataa
    32461 aaacgataca aaagttaatt cagaaaatga attagctgaa gaagaatgta aagttctaga
    32521 tactcttaaa gaaaatgtag aaaaagaaaa tatagatgca tgtatagagt tttggaatga
    32581 atataagaaa aatcatgaaa atataaaagg agctgaaaat ggttgggcag ctgctgttga
    32641 atactatgtt aaaaaagaag caggacaacc tataactcaa gttcaaatat caaagaaata
    32701 cgatataagc tctagtacac taggaaagag atacaaggat ttaaaaatat cttaattaat
    32761 tataaaaagc tttaagtcat agataaagaa tctatagtat aatatatgta taatgtttag
    32821 aaagaggtat taataatgag tcttagttta ggaaatgcaa ttgctgtatc aacgaacttt
    32881 ataaaatcta acccagctgt acctgtgtac aacggagaag aaatatatgc agttatttat
    32941 catatagaaa taggatataa taatggtgta tcacctgata ccaaacaata tataataata
    33001 gactataaag agtttgattt atctatggat aaaaaaaatg aactaataaa tattgctaaa
    33061 gagtactgta aatctaaagg tattgtagaa aacgaaaacc ttgaaataaa ccttttagac
    33121 aatgaagaag cagagaactt cttagaaaag gtgtttaata atatgaaggt tataagaggt
    33181 cttataacta aaaaaggata aataaatgga ctatatagga atagaaaata taacacctta
    33241 tgaaaataca tatgaattta gtgtatatga atatgatgat gaaatcacct taggtagtga
    33301 aaagttatat gtatgtgaat taagggttgt attgattaaa gttaattctc tgtatgttga
    33361 aagattgcat aaatcagttg aagcaatggt cttagtaaaa aacttgaaaa aagatttaga
    33421 taaaacactt gttgtaaaca aaataaagaa ttttgtgcta gatgagattt gggtagaaaa
    33481 tctagtaaaa gagaatatag aagttatatt tgtagaaagc taggaataac cctagctttt
    33541 ttatattaca atctaagaga ggaaaacaat atgttaagag tatctaatgt aaaacttgga
    33601 attgataaag atatatcttt attaaaagat gttatactta agaagctaaa aataaaagaa
    33661 aaaaacttag tcaaatatag tatatataaa gaatctatag atgctagaaa aaaaggaaaa
    33721 atggaatttg tttattctgt agatgtagaa gttaaagatg aaaataaaat acttaactca
    33781 aaaataaaag atgtaacaaa aataaaggaa atcagatacg taaatgtacc tgtgggtgat
    33841 aaaaaattaa agaataatcc tttggtaatt ggtagtggac cagctggctt gtttgcaggt
    33901 ctgcttttag ctcaaatggg ttatgaacca atcatacttg aaagaggtct tgatgtagac
    33961 agtagaacca aagatataag tgatttttgg acaactagaa aattaaaaaa taattcaaac
    34021 gttcaatttg gagaaggtgg agcaggaact ttttcggatg gtaaacttac aactagaata
    34081 aaagatatac gatgtagaaa agtattagaa gagttagttc agtttggagc accagatgaa
    34141 atattatact cacataagcc acatgttgga acagatatat taaaaaatgt agttaaaaat
    34201 ataagaaatg aaataataag tttaggtggt caagttagat ttaattcaaa agtaacagat
    34261 atagttgtat caaatgattc tatacaatct gtaataataa atgatactga aaaaatagat
    34321 acagatacaa ttatattagc tgttggacat agtgcaagag atacttatga aatgttgtat
    34381 tcaagaggta taaaaatagt tcaaaaacct tttgcaatag gagctagagt tgaacatcca
    34441 caagatttaa taaataaagc acagtacaag gatttttata atcatcctag gttaggagct
    34501 gcagattata gacttataga gcatgtttca aatggaagaa cagcatatac tttttgtatg
    34561 tgtccaggag gtagtgtcat agcatctgca tcaaatgatt ttgaaatagt tacaaatggt
    34621 atgagtgaac atgcaagaga taaaataaat gcaaatagtg catttttagt aaatgtaacg
    34681 ccagaagatt ttaagagtga taatccacta gcaggtgttc atttccagca gaagtatgaa
    34741 aaattagctt ttgaattagg tggaaaaaat tataatgcac cagttcagct tgttggagat
    34801 tttataaaca ataagacttc tttgaattta ggaagtgttg agccatcata tagaccagga
    34861 tatacactta caaatttaag tgaatgtttg cctagcttcg taacagagac tatgagagaa
    34921 gcgtttatat ctcttgataa aaaattgaat gggtttgcaa tgtatgatgc tgttttgacg
    34981 ggagtagaaa ctaggtcatc atcaccaata agaatagtaa gagatgaaaa tactttagaa
    35041 tcagtgagta ttaagaatct atatccatgt ggtgaaggtg ctggatatgc aggtggtata
    35101 gttacagcag cagttgatgg tataaaatgt gcagaaaaaa taatacaaaa atacaccaat
    35161 aatacaaaaa tttaacataa acttaatgat tttttaatat ttaacatgaa tttaacatta
    35221 tcactcctat aatttgataa aatacaatag gttataaaat ttttagatac agtaatctct
    35281 ttacaaggag gaaataattt gaacattata ataagtctaa tgggtggatt aggtctgttc
    35341 ttatatggta tgaaccttat gggagaaggt cttcaaaaat ctgctgggac aaagctaaaa
    35401 aagataataa aactacttac tagtaaccta tttatgggag ttttggtagg tacaggagtt
    35461 acagcagtaa tacaaagttc aagtgctact actgtaatgg ttgttggttt cgtaaatgca
    35521 ggaataatga ctttaaaaca ggcaatagga gttataatgg gtgctaatat agggactact
    35581 gttacagccc aattggtatc tttcgactta actggtatgg ccccagtagc attaggtgta
    35641 ggtattatac tttatttatt tggaaataag cctagaataa aaaatatagc cgaaatactt
    35701 ataggttttg gtatattatt tacaggtatg gattttatga agatggcagt ggagccacta
    35761 agagactatc aaggatttac tgacttactt gttacatttg gtagatatcc actacttgga
    35821 ttattattgg gatttgggat tacagcaata atacaaagtt caagtgcatc tatgggtatg
    35881 ttggttgcac tggcagcaga aggtctagtg ccattatcag cagcactgcc aattctttat
    35941 ggccaaaata ttggtacatg tgtaacttca ctgttatcaa gtattggtgc taacaaaaat
    36001 gcacgaagag cagctatgat gcatctaatc ttcaatgttt taggaacggt gatattttta
    36061 atattcttga ataaaccagt agtaagcatg gttacaagtt gggacccaag caatgttgca
    36121 agacaaatag ccaatacaca tacattgttt aatataatat ctgtattgat acttttacca
    36181 tttacaaatc ttattataaa actagctata aagcttgttc ctgatagagc aggtgatata
    36241 gatgaagatg aaactaaaac tattaaatat atagatgata gaatgataga aactccttct
    36301 atagctcttg caaatacgat aaaagaagca cttcgtatgg gtgagaaggc gaaggaaagc
    36361 ctaaatgcat ctatggaagc tttagtagaa cattcaactg aaaaaataga taagacatat
    36421 aggcgagaga gattaatcaa tgatttacag aaagctattt taaattattt acttaaactt
    36481 tcaaaagcac ctttagatga tgattcaaga gaagttgtgg atactttgtt taatacagtc
    36541 aatgatatag aaagaattgg tgaccacgct aaaaatatag ctgaattatc gcaagttgca
    36601 atagattcaa atatttcttt ctcagaagaa ggacaatctg aacttgatgt tatgtataat
    36661 agagttgttt cagcatatac ttatgcatta gaatcaatga gaactgataa tgttgattta
    36721 gcttgtaagg ttataaaaat tgaagaacaa gttgatataa tggagaaatc ttgtagagct
    36781 aatcacatgt atagattgaa caataatcta tgtagtatag aaaatggagt tatttattta
    36841 gacgtaataa gtaatttaga gagaatatct gaccatgctg tcaatatagc acaacaagtt
    36901 atagcaaaga gattaggaaa tgattaaaaa taattaattt aaaataatat aaaatttaaa
    36961 atagaggata aataaaagag aaactttaaa tgatacgttt agagtttctt tttttgtaaa
    37021 tttatttgac taaaattttt aaatttatac atagttatag tatttagaag aatcgatttc
    37081 ctgataataa atgatgagat atgtatgatt ttgtggcaaa cttttaaaaa aaacacctat
    37141 attttgtgtt ataatctctt taaaacgaat atgctgaaaa gagggattta aatgggaaaa
    37201 ataaattttg attatagtaa agctacagag tttttttgtc aaaacgaaat agatgtcatg
    37261 caaccatatg tagatgttgc gcacgacatg ttacataata aaactggttt aggaaatact
    37321 tttttaggat ggatagacct tcctaaaaat tatgataaag aagagtttga cagaataaaa
    37381 aaatctgctg agaagataaa atcagactca gatgttcttt tggtaatagg tataggaggc
    37441 tcttatttag gttcgagagc tgctatagat atggtaagtc attcttttag gaatggactt
    37501 aaaaaagagc aaagaaaggc tccagaagta tattttgtag ggcataatat aagctcaaca
    37561 tatattatgg atttattaga tataattgaa ggaaaggata tttctgtaaa tgtaatatct
    37621 aaatcaggaa ctactacaga accagctctg gcttttagaa tatttaaaga ttacttagag
    37681 aaaaagtatg gtaaggaaga agcaagaaag agaatttatg caacaacaga tgcaagtaaa
    37741 ggtgcactta gacagttagc tacagaagaa ggatatgaga cttttgtaat accagatgat
    37801 gtaggtggtc gtttttctgt attgacagca gttgggttac ttcctattgc tgctgctgga
    37861 cttgatattg atgctatgat gaaaggcgca aatgatgcta gagaagcatt tcaaaatcct
    37921 gacttaaaaa gtaatgatag ttatagatat gctgttgcta gaacaatttt acatagaaaa
    37981 ggaaaagatg tagagttatt agtgaactat gaacctcaac tacattatgt aagtgagtgg
    38041 tggaaacagc tttatggaga aagtgaagga aaagaaaata aaggtttatt ccctgcttct
    38101 gtagatttct caacagattt acattctatg ggtcaataca tacaagatgg aaaaaggctt
    38161 ttatttgaga cagtacttaa tgttgaaaac tgtaagagaa atataactat aagttcagag
    38221 gaagtagact tagatggttt aaactattta gcaggtaaga ctgtagattt tgtaaatcat
    38281 aaagcttttg aaggaactct attggctcat acagatggaa aagtacctaa tttagtaata
    38341 aatatacctc aactagatga gtataatttt ggatatttag tttatttctt tgagaaggct
    38401 tgtggaataa gtggatattt attgggagtt aatccatttg atcaaccagg agtagaagct
    38461 tacaagaaaa atatgtttgc tttactaggc aaaccaggtt atgaaaaaga aaaggaagag
    38521 ctagaaaaaa gacttaaata attttaaata gttaaggttt aattaagatt aaaataatat
    38581 aatgaaatca tcaaaaagga gtttactcaa aatagatgat ttcatttttt ttatgaaaaa
    38641 ttgggaaaaa tatattttga taatttatat tatattaaga tagggagtgg tatgagatgt
    38701 caagaagaaa gaaagggata agtttagtaa tattagttgc tataataagt tcaatactta
    38761 gtagttttct aacaataatt ttagttaagg acaatttagt aagtaaatct acaggaagtt
    38821 ctacgccgat agttgtaaat gatgatggta agagtcaaaa tatttatcaa gcagttgcag
    38881 aaaaagctac gccatctgtt gtaggtatta caacaactag tgttgatact agtaatatgt
    38941 ttgcaatacc aactgaaaca caaggtgtag gaactggaat catagttgat tcaaatggat
    39001 atatacttac taattctcat gttatatcag atggtcaagc tacaagtgta aatgtattat
    39061 tcaatgatgg ttcaacaact tcaggtaaag tagtatggtt tgaccaacaa cttgatttag
    39121 ctatagttaa ggttgataaa actggactaa caccagcaga atttgctgat agtgacaaag
    39181 taaaagttgg agatatatca atagcaatag gtaatcctct tggattagat tttcaaaaaa
    39241 cagttactca agggataata agtggattag atagaactat acaaacagaa aaaactaata
    39301 tgactggttt attacaaact gatgcaagta taaatgcagg aaatagtgga ggaccattgt
    39361 taaatcaaaa aggtcaagta attggtataa acacagcaaa agcttctcaa gcagaaggat
    39421 taggatttgc aataccaatc aatacagcta agagtatagt tgaagaagta atcaaaaatg
    39481 gaaaatatga aaaagtaact ttaggcataa aaggtacaga tgtatcaaat tatgaagcag
    39541 caacaggtac aaaattaagt actgataaag gtgtttatgt tgcagaagta atatctggtt
    39601 catcagcaga aaaagctgga gtaaaggtag gggatattat aactaaagta ggagatacag
    39661 atataacagg tatgaatgat ttaaataaaa agttgtatac tttctcaaaa ggtgctagta
    39721 caaaaataac agtaaataga ggcggaaaag cagtaacaat aaatgtgaat ttctaaatat
    39781 gaccagaaag atagagacta catggtaaag tgtagtctct atttttattt aatttttata
    39841 gtatatacat ctaaattaat taaaatgatg tattgtttat agtttattgc tatatttt
//
LOCUS       DAEQAF010000029        38440 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.030, whole genome shotgun sequence.
ACCESSION   DAEQAF010000029 DAEQAF010000000
VERSION     DAEQAF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38440
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.030"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(140..433)
                     /locus_tag="KRN00_001581"
     CDS             complement(140..433)
                     /locus_tag="KRN00_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBH1827448.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(439..654)
                     /locus_tag="KRN00_001582"
     CDS             complement(439..654)
                     /locus_tag="KRN00_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827449.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            1102..1500
                     /gene="tnpA"
                     /locus_tag="KRN00_001583"
     CDS             1102..1500
                     /gene="tnpA"
                     /locus_tag="KRN00_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBH1827450.1"
                     /translation="MYKSNKNIVYDCKYHIVFCPKYRKAVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIENQQVRTKK"
     gene            1497..2660
                     /locus_tag="KRN00_001584"
     CDS             1497..2660
                     /locus_tag="KRN00_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1827451.1"
                     /translation="MIKTHRVKLNLTRTQFELVREKQMESANCWNYIVNLSKEYYFEH
                     KQWIKKNDIQKLIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYETHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            complement(2915..3427)
                     /locus_tag="KRN00_001585"
     CDS             complement(2915..3427)
                     /locus_tag="KRN00_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1827452.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            3877..4353
                     /gene="purE"
                     /locus_tag="KRN00_001586"
     CDS             3877..4353
                     /gene="purE"
                     /locus_tag="KRN00_001586"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBH1827453.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            4359..5057
                     /locus_tag="KRN00_001587"
     CDS             4359..5057
                     /locus_tag="KRN00_001587"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBH1827454.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            5069..6436
                     /gene="purF"
                     /locus_tag="KRN00_001588"
     CDS             5069..6436
                     /gene="purF"
                     /locus_tag="KRN00_001588"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBH1827455.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            6430..7506
                     /locus_tag="KRN00_001589"
     CDS             6430..7506
                     /locus_tag="KRN00_001589"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBH1827456.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNAAYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            7500..8093
                     /locus_tag="KRN00_001590"
     CDS             7500..8093
                     /locus_tag="KRN00_001590"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBH1827457.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKLKLQGRRVFINE"
     gene            8086..9618
                     /gene="purH"
                     /locus_tag="KRN00_001591"
     CDS             8086..9618
                     /gene="purH"
                     /locus_tag="KRN00_001591"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBH1827458.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSYDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            9629..10879
                     /gene="purD"
                     /locus_tag="KRN00_001592"
     CDS             9629..10879
                     /gene="purD"
                     /locus_tag="KRN00_001592"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBH1827459.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            10904..14710
                     /locus_tag="KRN00_001593"
     CDS             10904..14710
                     /locus_tag="KRN00_001593"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBH1827460.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLRTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSVDGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            14916..15788
                     /gene="rfbD"
                     /locus_tag="KRN00_001594"
     CDS             14916..15788
                     /gene="rfbD"
                     /locus_tag="KRN00_001594"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBH1827461.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENTEVNVVNDQFGTPTSTVDLAKIIIKIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            15897..16766
                     /gene="rfbA"
                     /locus_tag="KRN00_001595"
     CDS             15897..16766
                     /gene="rfbA"
                     /locus_tag="KRN00_001595"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBH1827462.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGLNITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            16815..17372
                     /gene="rfbC"
                     /locus_tag="KRN00_001596"
     CDS             16815..17372
                     /gene="rfbC"
                     /locus_tag="KRN00_001596"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBH1827463.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            17410..18393
                     /gene="rfbB"
                     /locus_tag="KRN00_001597"
     CDS             17410..18393
                     /gene="rfbB"
                     /locus_tag="KRN00_001597"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBH1827464.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVSSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKMILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            18423..19091
                     /locus_tag="KRN00_001598"
     CDS             18423..19091
                     /locus_tag="KRN00_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBH1827465.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            19100..19528
                     /locus_tag="KRN00_001599"
     CDS             19100..19528
                     /locus_tag="KRN00_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBH1827466.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            19552..19866
                     /locus_tag="KRN00_001600"
     CDS             19552..19866
                     /locus_tag="KRN00_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1827467.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            20018..20293
                     /gene="flgM"
                     /locus_tag="KRN00_001601"
     CDS             20018..20293
                     /gene="flgM"
                     /locus_tag="KRN00_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBH1827468.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            20298..20714
                     /locus_tag="KRN00_001602"
     CDS             20298..20714
                     /locus_tag="KRN00_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBH1827469.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKQTTTYNSYGNIRK"
     gene            20732..22042
                     /gene="flgK"
                     /locus_tag="KRN00_001603"
     CDS             20732..22042
                     /gene="flgK"
                     /locus_tag="KRN00_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBH1827470.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            22061..22993
                     /gene="flgL"
                     /locus_tag="KRN00_001604"
     CDS             22061..22993
                     /gene="flgL"
                     /locus_tag="KRN00_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBH1827471.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            23009..23401
                     /locus_tag="KRN00_001605"
     CDS             23009..23401
                     /locus_tag="KRN00_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBH1827472.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDSGC"
     gene            23395..23607
                     /gene="csrA"
                     /locus_tag="KRN00_001606"
     CDS             23395..23607
                     /gene="csrA"
                     /locus_tag="KRN00_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBH1827473.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            23629..24024
                     /gene="fliS"
                     /locus_tag="KRN00_001607"
     CDS             23629..24024
                     /gene="fliS"
                     /locus_tag="KRN00_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH1827474.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIARAAILD
                     KNTQKAHRELVRVQDIFTELMVTLDQNAGQWAKDMYKVYDFVRYELSRANIRKDIQVI
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            24024..24380
                     /gene="fliS"
                     /locus_tag="KRN00_001608"
     CDS             24024..24380
                     /gene="fliS"
                     /locus_tag="KRN00_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBH1827475.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQNAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            24401..25924
                     /gene="fliD"
                     /locus_tag="KRN00_001609"
     CDS             24401..25924
                     /gene="fliD"
                     /locus_tag="KRN00_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBH1827476.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSINSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVRQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKFANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKSKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRAFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            25927..26262
                     /gene="fliT"
                     /locus_tag="KRN00_001610"
     CDS             25927..26262
                     /gene="fliT"
                     /locus_tag="KRN00_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBH1827477.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYINISSKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            26364..27236
                     /locus_tag="KRN00_001611"
     CDS             26364..27236
                     /locus_tag="KRN00_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBH1827478.1"
                     /translation="MRVNTNVSALVANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSLQSSNETN
                     TAEERQKVADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTTN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNVDGASGTDAAKQMVSSLDMALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            27329..29470
                     /locus_tag="KRN00_001612"
     CDS             27329..29470
                     /locus_tag="KRN00_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1827479.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TINISRKYTENVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLESAPGYLITSLVKTYLYLGKHKKCEKLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRQNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYFYIMYSYKYIRYIYSNLSDFELKKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILICELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMLENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            29494..31371
                     /locus_tag="KRN00_001613"
     CDS             29494..31371
                     /locus_tag="KRN00_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBH1827480.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKRQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSSINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIADIEKVKLDYKKDFFDYIILGDILEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMVNLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEIFCFIEGKKY
                     E"
     gene            31364..33478
                     /locus_tag="KRN00_001614"
     CDS             31364..33478
                     /locus_tag="KRN00_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1827481.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVANINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASAILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAIDDSGGEVISLDLISDDYLKRAMALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     ASQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYMESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIKRYNTSEFDRDKIKEKQSEIKHFVIDKHCIEIKNYIDKIYNEANHHKVKYNLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            33487..34482
                     /locus_tag="KRN00_001615"
     CDS             33487..34482
                     /locus_tag="KRN00_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBH1827482.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNSIT
                     NKLEIYLREQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            34574..35806
                     /locus_tag="KRN00_001616"
     CDS             34574..35806
                     /locus_tag="KRN00_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBH1827483.1"
                     /translation="MKRLMILGSIKYFENIVISAKKEGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKSIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAIMKKYFKNNAIPTTDYCIIESLKDLEKIQRLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLLYPSKYCFQYEEEIKSIYQNITQAFDIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIELYEDERQDCGRVYGIANNIFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            35826..36770
                     /locus_tag="KRN00_001617"
     CDS             35826..36770
                     /locus_tag="KRN00_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBH1827484.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHMIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            36864..37271
                     /locus_tag="KRN00_001618"
     CDS             36864..37271
                     /locus_tag="KRN00_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBH1827485.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKVIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            37358..>38440
                     /locus_tag="KRN00_001619"
     CDS             37358..>38440
                     /locus_tag="KRN00_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBH1827486.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISKGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIIN"
BASE COUNT        15655 a         3915 c         6962 g        11908 t
ORIGIN      
        1 ttatatgttt agattgtgag caatctattt tatattaaaa atagattatt tagaagaagg
       61 ggaaatctta aaaaaatttg aatatcccct ttttattatt taattaaaat gaaatagtta
      121 gaaatatatt ttatttagtt tagtcaataa cattttggga ttctttataa ctacatgtta
      181 actgttgaat aggtttatca tatggtttaa cccatccttt attaatactt aattctgtaa
      241 gtgctgtgtg accttctacc atttgagtta atgaagctga atatatagct cttaattcag
      301 gtgtactact tgtcaatgca gaattaagat acatattggc agatgcttta gcagatgaaa
      361 gcatacttaa cattattact ttatcgtcta tataagtatt gttcttaatt agattttcta
      421 tcatatttct catgttatct atacctcctc agaaattagt atttcatttt caactataaa
      481 ttgttgtata gctttaattc ttccttctgt tgctaatata ctagattctg attgtctttt
      541 taggtcttca tctgatatta acatatttat tgctctttgc ataagtaatc cgtcagactc
      601 catttttata attgctgcta aagatatttt ttcagtttct gaaagtattc tcatttaatc
      661 atctcctata ttgtaattta tgctttaata gtatgtcttt cttttcaagg aaataaccat
      721 tacacttttt tacagtattt tatattctct ttatatcaaa atttagtcga cctaatatat
      781 taatataatt ttgtaggata tttatcatta aatatctata aaataaatta tttgaatatt
      841 cataaagcaa aatttatttg tatgtacttc ttcaagagtc aatatgagtt ttttcaaaaa
      901 attaattttt atgataatca ttaagggcta tatttttctt aaagttgtga ttatcattat
      961 taatttacaa taaaattgcc gaaaagccct ctcctttagg tgtagggatg aaaggtaagg
     1021 tcttaatata aaaaaagtta gaataatgct tgtaatctaa taccgctact gataccctat
     1081 attttggagg tgttagtttt tatgtataaa tctaacaaaa atatagttta tgattgcaaa
     1141 tatcatattg tattttgccc taagtatcgt aaagctgttt tagttggcga agttgaaaag
     1201 atgttaaaag aaatactacc atataaagca gatgaacttg gagcagaaat aatagaaatg
     1261 gaaactgata aagaacatgt gcacttatta atatcttgtg accctcaata tggaattcat
     1321 aaagtagtaa aaggtttaaa aggctttagt tcgagagtat taagagagaa ctttccacat
     1381 ttaaagtcta gtatgcctag catgtggact aatagctatt ttgtaggtac tgttggttct
     1441 gtgagtttag aagtagttaa acaatatata gaaaatcaac aagttaggac aaagaaatga
     1501 taaaaactca tagagtgaaa ttaaacctaa ctagaacaca atttgaatta gtaagggaaa
     1561 agcaaatgga aagtgctaac tgttggaact acatagttaa cttatctaaa gaatactatt
     1621 ttgaacataa acaatggatt aaaaagaatg atatacaaaa gttaatcaaa ggtaagtaca
     1681 atcttcatag tcaaactatt caagctatat cagataaatt tgatgcaaat agaaagacta
     1741 tatcagaatt aagaaaaaaa ggtaatacta aagcaaaata tccatacaag actaagaaat
     1801 tttatataat accttttaaa gctagtgcta ttaatagaaa tgctaaaggc aacttaaaat
     1861 tatcaatgtc aaaaggcagg tatttagaat tagattttaa tgttgagaat ataaaaactg
     1921 ctgaaatagt atggcgaaat ggatattatt tatactacac ttttgacaat gaattaaatg
     1981 gagttgtagc caaaggcact aataccgtag gtgtagactt aggggaaata cattcgatag
     2041 ctagtgtaac aaatgaaggt gtagggctta ttctatctaa tagagaaggc agaagtatta
     2101 aacaatttag aaataagatg tatgcttata tatctaaaag attaagtaaa tgtaaaaaag
     2161 gtagtagaca atcaaagaag ttatggagat taaaaaataa gataagaagt aaaacagata
     2221 atcagttaat gaatttatat catcaaacaa ctagaaagtt tatagacttt tgtgtagagc
     2281 agaaggtatg tgaaatagtt cttggggata taaaaggggt tgaaaaagat actaagaaaa
     2341 agaaaagatt aaacagagtt aatagacaga aaatatctca aatggagtat ggtcgaataa
     2401 aggactatat aaaatataaa gcaaaagagc aaggtattga agttaagtta gttaaagaaa
     2461 actacacttc tcaaacttgc ccaaagtgtt ctaaaaaaca caaaccaact ggtagaactt
     2521 atagttgtac ttgtggttat gaaactcata gagatatagt tggtgcttgg aatattttaa
     2581 ataaaaagca taaatatggt ttagtagatt ttagaataaa tcataagcaa ccaataaatt
     2641 taaaagtatc taccgtttga gccatgtgtg ggcgaataac tttaaggtag tagtggcgaa
     2701 gacaccgtcc gaagtagctt ggctttgtaa ccacctctgt tgtactgttt aagtataaat
     2761 aagtgtgtta gccaccaaga atccccttgc tttagctatg gggagtgtgt caacttagag
     2821 gttaattagg tgtttaatca aagttaatgc ctttagaata caaatgtatt ctaaaggcat
     2881 ttttactatg tattttcatt tatattacta aacattatct atttttatat acatttctat
     2941 gtattttatt ttcatcaaat cggtctataa actcattttt ttcttcacta tatccaatag
     3001 atataagtgc ataaggaact aattttaatg gtaagtctaa agtttgtcta actttattta
     3061 ccactttatt tttaggaaat actcctgccc aacaagcagc tagaccttga ttagtaactt
     3121 ctaataataa attttgtgtg caagcaccta aatcttgtat ccatttacca ggttttaaga
     3181 atttatctct atttccaagc actactatac ataatggtgc aaattctata tgctttgctc
     3241 tatgctgtga ctttgagagc tgtttcagca gttccttatc atctactata ataaattccc
     3301 aaggttgagc attttttgat gaaggtgctt gcatagctga ttttagtatt tcagttattt
     3361 tatcttcttc tatattttta tctatatatg ttcttattga acgtctattt tttataactt
     3421 ctaacataca gattctcctt taaataaaat tatttctatt tatataatat cattacttta
     3481 aattttagct attacttata taaagaataa actttgtgtt ggttttatct aagtaaaagt
     3541 aacattcaga actaaaaaac aagactataa atccaaagta ttaattaaaa aagaagtaat
     3601 aaaaaataat atacaagatt taaaaaagag tattgggctt aaaatttaat tagaaaacca
     3661 attttgagat aatctgtttt ttattttaac aaaaaaacat aaataaagtt cgatacgtag
     3721 cgaatgaaaa aattacaaga aatatttttt ttaaaaaatt tcaaaaaaga gttgataata
     3781 tatgtatatt aatataaaat ttaaggtgta taattcgtat aataatacga atgatttgta
     3841 gtgtaaaata acttataaac ggagagggga agtctaatga aagtagcagt agttatgggt
     3901 tcaaaatcag attatccaaa attagaagaa gggataaaac tgcttgaaaa atatggaata
     3961 gaagttgtag caagagcatt atcagctcat agaacaccag aacaactttc aatattccta
     4021 aaagaaatag aagatgatac tgatgtaata atagcagcag caggaaaagc agcacactta
     4081 ccaggtgtaa tagcttcaca aacattaatt cctgtaatag gattacctat taaatcatca
     4141 actatggatg gactagactc acttttatca atagttcaaa tgccaaaagg aatcccagtt
     4201 gcaacagtta caatagactt aggtttaaac gcagctttat tggcattaca aataatgact
     4261 ttaaaatacc caaaattaaa agaggatttg aaatcatata gagaagagat ggcacaaaag
     4321 gtgttagaag acgacaagaa tttaaggggg tagcagaaat gttattatat gaaggaaaag
     4381 caaaacaagt atattctaca gataatgaaa atgaatatgt tgtttattat aaagatgatg
     4441 caacagcatt taatggagaa aaaaaagcag aaatatcttc aaaaggtata ctaaataata
     4501 agatatcaac aataatcttt gaaatgttaa aagaaaataa tataaatact cactttataa
     4561 aaagtttatc agatagagaa atgttagtta aaaaagtaga gattttacca ttagaagtaa
     4621 tagtaagaaa tattgctgct ggttctatct gtaaaagagt tggtcttgaa gaaggtgtag
     4681 ttttcgatga gccaattttt gaaataagct acaaaaatga tgcttatggg gacccaatgc
     4741 taaatgatga ttatgcagtg gcaatgaagt tagcaactag agaagagtta aaattcttaa
     4801 gagaagaaac tttaaaaata aatgagttac taaaagcatt tttcttaaaa ttaaacctaa
     4861 agttagttga ctttaaaata gaatttggta aggattctga aggaaatata atattggcag
     4921 atgaagtatc accagacact tgtagacttt gggatgtaaa tacaaatgaa aagttagata
     4981 aggacagatt tagaaaagac cttggagacc ttgtagaagg ttatacggaa gtactttcaa
     5041 gaatgaataa taaataggag gcaaatgtat gtgtggagtt ttagggattt actctaataa
     5101 agatgtaact aaagaactat attattcttt atattctatg caacacaggg ggcaagaaag
     5161 ctgtggttta gctcttttag atgatggaga aattaagtac aaaaaagata tgggattagt
     5221 tggagatgtt tttaaggaaa atgaattatc taagttaaaa ggaaatatag ggattggaca
     5281 tgttagatat tcaacagctg gaggaagtca tgtttctaac tgtcaacctt tagttggaag
     5341 ttgtagaaaa agacaattag ccatagctca taatggaaat ctagttaatg caaattattt
     5401 aaaagatatg ctagaagaag atggatatat gttccaaact aattcagata cagaagtgat
     5461 tttatatata cttgctagat attacaaagg ggatatagta gaaagtttaa aagtgacaat
     5521 ggattatata aaaggtgcat atgctcttgt aataatgagt caagaagaat tggttgcagt
     5581 tagagaccca catggattca gacctcttgt acttggtaaa aagggtgatg aatatatatt
     5641 tgcatcagaa aattgtgcaa tagatatact tggcggagaa gttataagag atgtagagcc
     5701 aggagagata atagtagtca aagatggaga actaaaatca tatttttatt cagaaaatta
     5761 taaaccagtt aagaaaagtt gtatatttga acacatatac tttgcaagaa atgatgcaac
     5821 tatagacaat gtaaatgcat atgaatttag aattaaatgt ggtgagagat tagctcagaa
     5881 tgaaactgta aaggcagata tggtagttcc agttccagat tcaggttggc caggagctat
     5941 tggttatgca aatgctagtg gattaaaaat aagtgaaggc ttagttaaaa atagatatgt
     6001 aggaagaaca tttataaaac ctacacaaga agaaagagaa atagcagtaa aaataaaatt
     6061 aaatcctctt tcaacaataa taaaaggaaa atctataatt ttagtagacg actcaattgt
     6121 aagaggaact acatctaaac aattagtaaa atctttaaga gaagcaggag caaaagaaat
     6181 tcatcttaga ataacttctc ctccagtagc ttactcttgt tactatggaa tagatactcc
     6241 aaatcgctct aaattaattg catcaagtaa caacgtagaa gaaatgagag aatatattgg
     6301 atgtgatagt ttaaaattcc tagatataga aggaatgtta gatgcaacag aacataagtc
     6361 tactttctgt aaagcttgtt ttgatggaga atacccagtt aagaaaattg ataaggagga
     6421 actactttca tgttaacata taaagaatca ggtgtagata tagatgaagg aaatagagca
     6481 gtagacctta taaaaggtaa aataaaagga acttatgatg gaaatgtagt tggagattta
     6541 ggtaatttca gtggattata cagtttaaaa gattttgtag gtatgaaaga accagttttg
     6601 cttgcatcta cagatggtgt tgggactaag ttaaaaatag ctcagatgat ggacaagcat
     6661 gatactgttg gaatagattt agttgcaatg tgcgtgaatg atttaatttg tcaaggagca
     6721 aaaccattat tcttccttga ctatatagct cttgggaaat tagtgcctga gcatatcgaa
     6781 aaaatagttg gtggaattgc agatggttgt aaaatgtctg gttgtgcact aattggtgga
     6841 gaaactgctg aaatgcctgg aatgtatgga gaagatgact atgatttagc aggattttct
     6901 gtaggaatag cagacaaaga aaagattgtt tctggaaaca atgttaaatc aggagatgta
     6961 ttggttggta tatcttcaag tggagtacac agcaatggat tttcttttat aagaaagata
     7021 tttttagaaa cttacaatta taaaatggaa caatatgttg aagaactagg aatgacagtt
     7081 ggagaagcac ttttaacacc aactaaaata tatgttaaat tagctttaga tgtattagct
     7141 aaacatgaca taaaagctat agctcacata actggtggag ggcttataga aaatataaca
     7201 agagttatac ctaaagggtt aggactagat atcaataaaa aatcttggga gaagcctcct
     7261 atatttaaaa tgatagaagg ttttaatgct gttgatgaga gagaacttca taagagtttt
     7321 aacatgggta ttgggctagt tttaatagta gataaagaaa atgctgatga tgttgtaaac
     7381 tttataaata atagagaaaa tgacaatgct gcttatgtag ataaaaaata tagtgaatta
     7441 ttagaagata aagcgtatat aattggtgaa gtagtagata gtcatgaagg tgtagaatta
     7501 tgctaaatat aggagtttta atatctggtg gaggaacaaa tttacaagca gttatagatg
     7561 gtactgagtc tggagaaata aaaggtcagg ttaaagtagt tatctcaagt aagcaaggtg
     7621 cttatggtct agagagagct aaaaatcata acataaaagc aatttgtgaa actgatgaag
     7681 acaagataat agaaattctt aaggaaaata aaatagattt agtagttttg gctggttatt
     7741 taaaaataat cagcccaaag ctggttaatg agtttagaaa caaaatgata aacatacatc
     7801 catcattaat tccttcattt tgtggagctg gattctatgg agaaaaagtt catcaaggtg
     7861 ttatagatta cggagctaaa gtaactggtg ctacagttca ttttgttgat gaaggtgctg
     7921 atactggacc aatcataatg caagatgtag ttaaggtaaa tcaagatgat gatgcaaaga
     7981 cacttgcaaa aagagtgtta gaagttgaac ataggatttt aaaagaaagt ataagtcttt
     8041 tttgtgaaaa taaattaaaa cttcaaggta ggagagtgtt tataaatgag taagagagct
     8101 ttaataagtg taactgacaa gactggtgta gtggaatttg ctaaagagtt aaataaatta
     8161 gattatgaaa ttatatctac aggaaataca tttaaaacat taaaagaaaa tggtgttaat
     8221 gtaatgcaag ttgaagatgt tacaaatttt ccagaaatat tagatggaag agtaaaaaca
     8281 ttaaatccat atatacatgg tggtatactt tataaaagag ataaagaatc tcatgtagaa
     8341 actgtaaatg aacacaaaat acattcaata gatttagtag ctgtaaatct atatgatttt
     8401 gaaggaactt taaaagctgg aaaaagttat gatgaaataa ttgaaaatat agatattggt
     8461 ggaccatcta tgatacgttc tgctgccaaa aactataagg atgtaatagt agtagtagat
     8521 ataaaagatt atgattctat aatagaaaaa ttaaaaacag atacaatgac attagaagac
     8581 agaaaaaaat tatcatataa agctttctca actacaggaa gatatgatgc gttaatatct
     8641 agttattttg ctggagaagt tggagatacg tatcctgaca tattaaattt aactttccaa
     8701 aaagaacaaa ctttaagata tggagaaaat ccacatcaaa atggtttctt atattcacag
     8761 tcaaatgcaa aaaatccaat cttaaattat gagcaattag gcggtaaaga actttctttt
     8821 aacaacttaa atgatttaca tggatgttta gaagtaatga gagaatttaa agatagtgaa
     8881 gaagtagttt cagtagctat aaaacatgct aattcatgtg gggtaggttt aggaaaagat
     8941 gcttttgaag catatacaaa atgttatgaa gcggataagg tttcaatatt tggaggaata
     9001 gtaggaataa cttctactat agataaagct acagcagaga aattaaatga aatattctta
     9061 gaaatagtag tagcatatga ttttgaacca gaagctttag agatacttaa acaaaagaaa
     9121 aatctaagaa tattaaaatt agctaaaata gaaaatagtt tacaaccata tgaaatgaaa
     9181 tatttagatg gaaaattatt gatacaagat agaaataata tattagcaga aaaaagtgaa
     9241 aatgtaacaa aggaaaaacc aacagatgca caacttaagg acatggaatt tggtatgaga
     9301 gtagtaaaaa atatgaaatc aaatgcaatt gcaatagtaa aaaatggaca aactctagct
     9361 ttaggttgtg gacaaacatc aagaatttgg gcattaaaaa atgctcttga aaataacaaa
     9421 gataaagatt ttacaggagc tgttttagcg tcagacgcat ttttcccatt tgatgattgt
     9481 gtaacattag ctcatgaata tggaatatca gcagtagttc aaccaggtgg ctctataaaa
     9541 gataaagatt caatagaagc ttgtgacaag tatgatatgg ttatggtatt tacaggaata
     9601 agacacttca aacactaagg aggatattat gaagatattg gttgtaggcg gtggcggaag
     9661 agagcatgct atatgctgga aactaagcaa agaaaaaaat gtagaaaaaa tttattgtgc
     9721 accaggtaat gcaggaattg caaacgtagc agaatgtgta aatataggtg atactaatat
     9781 agaagaactt ttaaaatttg ccaaagaaaa tgaaataggt ctgacaatag taggaccaga
     9841 agtaccacta gttatgggaa tagtagatga gtttgaaaaa gaaggattaa gagtatttgg
     9901 acctaataaa aaatgtgctc aacttgaagg aagtaaagct ttttcaaaag aatttatgat
     9961 aaaacataac atacctactg caaaatataa agaatataca aacttagaag aagctatatc
    10021 agaaatagat agttttggat atccagtagt aataaaagcg gacggattag ctgctggaaa
    10081 aggtgttgta atacctgaaa atagagaaga tgctatagca actttaaaag aaatgatgtc
    10141 agataagaag tttggagctg ctggagataa aatagtaatt gaagagtttt taaaaggaat
    10201 agaaacttca attctagcat ttgtagataa tgatacaata gttcctatgg caagtgcaaa
    10261 agaccataaa aaagtaaaca actatgagca aggtccaaac actgggggaa tgggaacttt
    10321 ttcacctagt gaaatatata cagaagaatt agcaaataaa gtaaaagaga cagtattaga
    10381 aaaaacttta gaaggcttca aaaaagatgg acttaatttt aaaggtattt tatttgttgg
    10441 tcttatgata actgaagatg gagaaaaagt acttgaatat aatgtaagat ttggagaccc
    10501 tgagacacaa tctgttttat ttagattaga aacagattta catgagataa tggaagctat
    10561 actagataat aagttaaaag atatagaaat aaactatagt gatgatgaag ctgtgtgtgt
    10621 tatgcttaca tcaggagggt atccagacag ttatgaaaaa gggaaaatta taactggtct
    10681 tgaaaacttg gatgatgata tagtagtatt ccatagtggc actaagatgt ttgatggtaa
    10741 tttggttacc aatggaggaa gagtaattgg tataactgca aagtcaacta cagttaagga
    10801 tgcagcagaa aaagtttatg aaaacataaa gaagataaac tttgaaggaa tgcactatag
    10861 aacagacata ggaagataat ttttctaaaa tggaggataa ggtatgttga atactgaaaa
    10921 taaagactca atggttagaa gagtattggt tgaaaaaaga gaaggttttg accttgaggc
    10981 taaagcttta aaaaaagact tagtagaaag tttacacata gataatatag aaaatttaag
    11041 aatattaaat agatatgatg tagaaggaat atcagaagaa gtttatgaaa atgcagcaaa
    11101 gacaatattc tctgaaccaa atttagatgt ggtatattat gaagaaatac caaaattaaa
    11161 tgatgaaaga gtatttgcaa tagaatttct tcctggtcaa tacgaccaaa gaggtgattg
    11221 ggcagctcaa tgtgtacaaa ttgtaaatca agggataaga cctgctatta atacagcaaa
    11281 agtttatata ttatcaggca aaataactga tgaagagttt tctaaaataa aagattactg
    11341 tataaatcca gtagatagta gagaagcatc tttagagaaa ccagaaacgt taaaaatgga
    11401 aactgaaata ccaacaacag ttgaagtatt agatggattt atagatttag atgaaaatgg
    11461 attaagaaca tttgtaagtg aaaaaggatt agcaatgact ttaggagact tacaacacgt
    11521 tcaaaaatac tttaaagata cagaaaagag aaatccaact ataacagaaa taaaagtatt
    11581 agatacttat tggtctgatc attgtagaca tactactttt atgactgaaa tagaaaatgt
    11641 aaagatagaa gatggtaagt ttaatgatat agtaaaagaa gcgtatcaaa tgtatcttaa
    11701 ctcaagagac aatgtatatg tgaacagaca taaagatata tgtttaatgg atatagccac
    11761 tgttgcagta aaagaattaa agaaaaatgg gaaattaaat gacctagatg aaagtgaaga
    11821 aataaatgca tgtagtataa acgtagatgt tgaagttgat ggtaagatgg aaaaatatct
    11881 agtaatgttt aaaaatgaaa ctcacaacca tccaactgaa atagaaccat ttggtggagc
    11941 agctacttgt ttaggtggag ctataagaga cccattatca ggaagaagtt atgtttatca
    12001 agcaatgcgt gttacaggaa gtgctgaccc aagaacgact ttagaagata ctttacctgg
    12061 aaaacttatg caaagaaaaa taactacaga agctgctcat ggatatagtt catatggtaa
    12121 ccaaataggt cttacaactg gacaagttgc agaagtatat gatgaaaact ttgttgcaaa
    12181 gagaatggaa ataggtgcag ttatagcagc agcaccaaaa gagaatgtag taagagaaag
    12241 acctgaagca ggagatgtaa tcgttcttct tggaggaaaa acaggaagag atggctgtgg
    12301 aggagcaact ggttcatcta aagaacatag tgaagagtca atcttaactt gtagtgcaga
    12361 agttcaaaaa ggagatgctc ctaacgaaag aaaaatacaa agattcttta gaaataaaga
    12421 agttgctcaa atgataaaaa gatgtaatga ttttggagca ggtggagttt gtgttgctat
    12481 aggagagatt gctgatagct tagatataaa cttagactta gttcctaaaa aatatgatgg
    12541 acttgatgga actgagcttg caatttcaga gtcacaagag cgtatggcag tagccataaa
    12601 aaaagaaaat aaagataaat ttatacaatt agcagtagaa gaaaacttag aagctacaca
    12661 tgtagctaca gtaacagata caggatattt aagaatgttc tggaatggaa aagcaattgt
    12721 agatataaat agagagtttt tagatacaaa cggagtaaaa caaactactg atgttcatgt
    12781 tactaaagta gatgaagaaa atacattctt tagctctaat gaaatagtaa aagatgttaa
    12841 gtgtgcaagt atgaaagaca agtttacaaa agtactatct gaccttaatg tttgttctca
    12901 aaaaggatta gtagagatgt ttgataatac aattggtggt aatacagtac ttatgccatt
    12961 tggaggaaag tatcaagcga ctccaacaca aggtatggtt gctaagatac cagtacttgg
    13021 aggagaaact aatacttcta caataatgac ttatggatac aatccaaagg taggaaaatg
    13081 gagcccattc catggtgcct tgtatgcagt agtagaatct gtgtgtaaat tggttgctat
    13141 tggaggaaat tatagtacaa caagacttac attccaagag tattttgaaa aacttggtaa
    13201 caatccagaa aaatggggta aaccattctc agcactttta ggagcatttt atgcacaaag
    13261 taaatttgag atacctgcta taggtggaaa agacagtatg tctggtacat ttaaagatat
    13321 tgaagttcca ccaacattag tttcatttgc tgttgacaca gtagatgcga agaaagtagt
    13381 atctccagaa tttaaaaaag cagactcaaa agtagtaatg ttatgtgtaa acaaggcaga
    13441 aaatgatgtt gtagattttg aggaattaaa gagaaactta gataaagtaa gagaacttat
    13501 acatggaaat aaagttttat caacatatgc attaggattt gcaggtgtag gtgaagcaat
    13561 aagtaaaatg gcttttggta ataaaatagg atttaagttt agtgaagagg ctgaaaaagc
    13621 atttacagat gataaattat ttgaggctag ttatggaaat atagtacttg aattagcaaa
    13681 tgatgattta agtatgttag aaggatacaa ttatgttgtg cttggaagta cagttaaaga
    13741 agctagtata tttatcaaag gtgaagaact tgcattagat gaattatata aagcacattg
    13801 tagtacttta gagcctatat tcccaactaa aacagaagaa gtaaaatcaa agatagaaac
    13861 tataagttat atatcacaag gagaagctaa aaaatcatca ttaagtatag ctactccaag
    13921 agtatttata ccagcattcc ctggaacaaa ctgtgaatat gactctgcaa gagcatttga
    13981 aagagcagga gctaatgcaa gtataagagt atttaagaat ttaacttata aagacataga
    14041 agattctata gatacaatag taaacgaaat aaaatcttct caaataataa tgttaccagg
    14101 tggatttagt gctggtgatg agccagatgg ttctggtaaa tttatagcta ctgtatttag
    14161 aaatcctaga gtgcaagaag ctataaatga atttttaact caaaaagatg gactaatgtt
    14221 aggtatctgt aatggattcc aagtattaat taaattaggg ttagttccat atggagaaat
    14281 aagagttcca agtgaaagtg ctccaacact tacttacaat aatattggtc gccatcaagc
    14341 taagattgct agaactagaa tttcatctaa taaatctcct tggttagctc aaactaatgt
    14401 tggagatatt cataatatag caatttctca tggagaaggt aagtttgttg ctagtgaaga
    14461 tgttatgaga gaattaattg ctaatggaca agtagcaact caatatgttg actttaataa
    14521 tgaagctact tatgatattg agtttaatcc aaatggttca ttctatgctg ttgaaggtat
    14581 aaccagtgtt gatggtagag tgtttggtaa aatgggacat tctgaaagaa ttggtgagga
    14641 agtatataag aatattatag gtgaaaaaga ccaaaagata tttgaatctg gagttaaata
    14701 ttttagataa agctttgatg tttaattgat agctagaata tataatttag atatttagat
    14761 ttaaagagat gtaataatat gatgataatc atttaatatt acatctcttt tttatttatc
    14821 taagaaataa taagttcaac ctaagttaaa atacaagctg tgttataatt aattattaag
    14881 taaaattgaa tatttattgg agggcaacat aattaatgaa aatattaata acagggtcta
    14941 atggtcaatt aggaaaagaa ttggttaacc aattagaagc aatcaatcaa agtataaacc
    15001 aaccaaaata tgttatatta gctacaacaa gaagtgattt ggacatatcc aatcagacta
    15061 atgtagataa ttttattttg cataataaac ctgatgtagt tgtaaactgt gcagcatata
    15121 caaaggttga tgcatgtgaa gataatatcg aaattgcata caaaataaat gctttaggag
    15181 tgagaaatct agcaatagca tcagaaaaag ttaatgctaa gcttattcac atatcaactg
    15241 actatgtatt caatggtttt tctaaatatc catataggga agacaataaa actgaaccca
    15301 attctgtata tggaaaaagt aaacttatgg gagaaaaatt tgttgaacaa ttctcacata
    15361 agtactttat attgagaaca gcatggttat atggtaatgg gaataatttt gtaaagacca
    15421 tgataaaact ttctttagaa aatacagagg ttaatgtggt taatgaccag tttggaactc
    15481 caacaagtac agtagactta gcaaaaatta taataaaaat catggaaaca gaacattatg
    15541 gagtttatca tgctacatgt gaaggtgagt gtagttggta tgattttgcc aaaaagatat
    15601 ttaaactaaa aaatatagat ataaaagtaa atccaattaa gagtaacgaa tttaaatgta
    15661 aggctccaag accactatat tctgtattgg ataattttat gttgaagtta attggtttaa
    15721 attcttttag aaagtgggaa gaatccattg aagaatattt agaaagatat gatataaatg
    15781 aaaagtaaat gtattatttt gagaaaagaa aataagatat tataaaaaat ataaatattt
    15841 cttttattta tccgataatc ataatatgac aaaaacaaat ttaaggatgg aaaaagatga
    15901 aaggaattat tttagcagga gggtctggta caagactata tcctataaca aaatgtatat
    15961 caaaacaaac acttccaata tacgataaac caatgatata ttaccctatg tcggttctta
    16021 tgttggcagg gatacaagat atattaataa tatctacacc aagagatata aaagcatttg
    16081 aagaattatt tggagatgga agttcactag ggcttaacat aacatatgca attcaggaga
    16141 aagcaaatgg aattgcagaa gcgtttataa taggagaaga atttatagga aatgacagag
    16201 tgtctcttgt attaggggat aatatatttt atggatatgg atttagtgaa aggttggaga
    16261 atgcagttaa aagaaaagga gcaactatat ttgggtatca tgtaagtaat ccaaattcgt
    16321 ttggagttgt agaatttgat aaggatttta atgtattgtc aatagaagaa aaacctacag
    16381 ttcctaaatc taattatgct ataccaggat tatattttta tgataatgat gttgtagaga
    16441 tagcaaagct agttgaaccg tcagatagag gtgaattaga aataacctct ataaacagtg
    16501 aatatctaaa acgaggaaaa ctaaaagtgg aacttctagg aagaggtatg gcttggcttg
    16561 atactggtac acataaaggt ctattggatg cttctaatta tgttgaagtg gttcaaacaa
    16621 gacagggact gtatatagca tgtttagaag agattgcata tacaaaagga tatataagta
    16681 gagaacaatt aatgaaacta gccaagccac tgataaaaac tgaatatggt caatatctat
    16741 taaaattggc tagtgaagat atgtaatatg gtagataaaa tttattataa attttattaa
    16801 gggagtttat tataatggga aaaatcaatg ttataaagac taaaatagaa ggattatata
    16861 tagtcgaacc aaatgtattt tatgatgaaa gaggatattt tatggaaagc tataataaaa
    16921 aggattttat agagcagggt cttgatatgt gctttattca agataatgag tctagctcaa
    16981 gaaaaggcgt tttaagagga atgcattttc aggttaaata tcctcaagga aaattagtca
    17041 gagttacaga gggagaagtt ttcgatgttg cagttgattt aaggaaagat tcacaaacat
    17101 ttgggaaatg ggaaggtgta atattgtctg ataagaataa aaaacaattt tatattccag
    17161 aagggtttgc acatggattt ttagttttat cagaaaaagc agtatttagt tacaaatgta
    17221 caaattatta ttacccagaa tttgagaatg gctttatatg gaatgacaag caaatatcta
    17281 ttgagtggcc tttaaaagga attgaagaaa tatttttatc agaaaaggac aaaaaacaaa
    17341 aaagttttaa agatatttgt acaagacgtt aataaaaatt tattagaatt aacatttagg
    17401 agaaaaaata tgaaaaaaat actgataact ggaggagcag gatttattgg gagtaatttt
    17461 atacattata tgcttaacaa gtatgtagat tattttattg ttaacctaga cttgttgact
    17521 tatgctggta atttagagac attaatagaa atacaagaca attccaatta taaatttgtt
    17581 aaaggagata tttcaaatag ggagcaggtg tataagctat ttgaagaaga aaggtttgat
    17641 atagttgtta actttgctgc tgaatctcat gtagataggt cagttgagaa tcctgattta
    17701 tttattaaaa caaacattat aggaacacaa gtacttttag atgcatctat aaaatatgga
    17761 gttaaaaggt atcatcaaat atctacagac gaagtgtatg gtgatttacc aattgataga
    17821 aaggatttat tctttacaga acaatcttct atcaatccaa gttctccata ttcagcttct
    17881 aaagcatcag cagatttatt ggtaagttct tattatagaa catatggatt gttaacaact
    17941 atatctaggt gttccaacaa ttatgggcca tatcattttc ctgaaaaatt gattcctctt
    18001 atgattttaa atgctttgga aaacaaacaa ttgccagtat atgggaatgg ggaaaatgta
    18061 agagattggt tacatgtata tgaccattgt actgctatag acttaataat acataaagga
    18121 aatatagggg agatttacaa tataggaggt cataatgaaa gaagtaatct agaagtagta
    18181 aaaatgatat taaatctttt aggtaaatct gaagagttaa tatcctatgt aaatgataga
    18241 cctggtcatg atttaagata tgctattgat gcaactaaaa tagagaatga gttaggttgg
    18301 aaggcaaaat atgactttga tttgggtata aaagaaactg ttaagtggta tatagaaaat
    18361 gaatcttggt ggaaagctgt tttatcagta taactttaaa atttagaaag gggcgtttta
    18421 tattgaatga gataagttca ctaattaata tattagcatt gactcaatta tctggtagta
    18481 atactacaaa tcaatgtaat tgtacatata ataattcatc tggatttgat atgattatga
    18541 tgaccttgtt aaaagcatta tcacaaaata atcaacatac ttctaatagc tacaatttat
    18601 tgtctaattc tgagaattta tttaatgaac ttgataatgt agtaaataat accactagta
    18661 gatttataga tgttgataca aaagataaaa atgtaaagtt gagaattgaa aatgctgtag
    18721 atcaagcatc aaaaaaatat aacgtagatt caaatcttat aaaagcaata attaaagttg
    18781 aatcagattt taatccaaat accgtttctt ctgctggtgc taagggtctt atgcaactta
    18841 tgccagaaaa ctgcagagac ttaggagtta cagacccttt taatatagaa cagaatatag
    18901 atgctggaac tagacatatt aaggaataca ttgatatgtt tggagggagc atagaaatgg
    18961 gattgatggc atataatggt ggtcctggaa gaatgaaaag tagaggagta gaatcaatct
    19021 ctgacctgta taaaatgcca aaagaaacac aaaattatat tcctaaggtt atgaaatatt
    19081 atagagggta ggctttatta tgggaataaa tatagataag ctaaacataa gtccaagtat
    19141 aaatatggag gttaaaaaac taaaagagag taataaattt tctgacaaat taaactcttt
    19201 aaaacaatct tcttcattgg aagatataaa acgaaatttg gaaagtgtaa aaaaggcagg
    19261 agaaaggctt gtacttactc aaaactatgg cgatattagt atatataaaa atgcagtaaa
    19321 agaataccta aaatctgttg tagataatat gtattcactt gataaaaata gtagcttttg
    19381 ggagcatcag tattataaga atgtaaagat tgttgatagt aaacttgagg atatgactag
    19441 taagttaatt agtgaagaaa aagaaaacat agatattgtt tctactgttg acatgataca
    19501 aggcttattg atagatatgt atagataagg ttatacaagg agaaaaattt tatgaatagc
    19561 aaaaaagagg atatatatga attgaatttt gggcaattaa tagaagaaaa atctggtgtt
    19621 atagaagaaa atcaaaatgt ttttaatgca aaagtaaatg tagctgtttc tataggaaat
    19681 acaacagaaa caataaaaaa tatattagat ttaaaagaag gctctataat aaaattaagt
    19741 aagaatgtgg atgaaaaatt agatatatat gcaaacgata gattgtttgc ttatggagaa
    19801 agcattatta caaatgagag gttatctgta agattatcta aaatagaaga tccagatgta
    19861 aattagcatt ttaaatagta tccctttagg ctattctgta tgagtttagc taaggggata
    19921 tttttataaa aaatttaaaa tatgtgtgaa ttatataaat atttttattt tatgagcgat
    19981 aactaaatta taagtatgta attttggagg tgaaactatg gatattaaaa atgtaagttc
    20041 aaacattgta gtgaataatt atttaaagaa tacatctggt ataaaaaaag tggaagaggt
    20101 taaaaaaatt aataaaacag acaagataga gttatctaaa tttgcaaagg aaatggcaag
    20161 tgtgtcaaat atgagtgatg agaatattag gaataaaaaa gtcgatgaaa taaaaaatgc
    20221 attagaaaat ggaacttaca aaataaaacc aaaagaaatt gcgaaaaaaa tgatagagga
    20281 tatgcgagga taaagtcatg attacagact taaaagttat aatatatgaa gaaaaaaata
    20341 taattagtaa gatgatggaa ttattaaaag aacaatttga ttatatagtt gaaaaagact
    20401 tagaaaattt aaatatgtta aatcctaaac tagaagatat tagcagggag cttgcatcca
    20461 tagaaataaa gagaagacaa ctttttggtg atgatatttc aatgagtgaa gttgttgaaa
    20521 atagtaatga tggatactta aaagaaatat atacagactt gaaacacatt cttgctttag
    20581 ctaaaaatca acaagaatca aatgattctc taataaagaa agaacttatt tttacgaaaa
    20641 aaatgattaa tttcataaaa ccagctgata agcaaactac aacttataat tcttatggaa
    20701 atattagaaa ataaatatta ggaggagaaa tatggcagga ttattttcca ttttaaatac
    20761 agctaattca ggaatgaatg cgcaccaaaa agcaatacag acaatttctc ataatataag
    20821 taatctagat acagacggtt attctaggca aaggaccgag tttgccacaa atagtccaat
    20881 gtatatgcct agtttgagta attcaattgc aagaggacaa ttagggactg gagtacatgt
    20941 aacggatgta acaagagcta gaaatagttt ttatgattac caatttaggg cagaagctca
    21001 taagtatggt aagacagttt caaaatatga ttattacaat actatagaaa ctatactaaa
    21061 tgaaccatca gactatggaa tatctgcagg tatagatgat ttttttaaag gatgggagtc
    21121 attatcaaag gatataaata gtgacagtaa aaaaagtcta gtggtagaaa acgcatctaa
    21181 tttagcaact ttaataagtg aaagttataa gaagcttgat aagttaaaag aagatataga
    21241 ttctaatata gacactgaga taaaacaaat aaatgacatg ttaaaaagtc ttgaagattt
    21301 aaataaatct attgatatta tatctggttc tggctctaca ccaaatgatt tacttgatga
    21361 aagagataga attttagata acttgagttt taaactagac tttgaaaata gtgatgttaa
    21421 aaatatgctt gcagatggta aattagaact taatgaatta aaaaatccag atggaacttg
    21481 gaaaacaggt atatcaggga ccttacaagg cttgtttgaa atgcatggta agattgatac
    21541 atataaaagc gatttaaaag atgtatctga tggattagct aaacagataa atgatgttta
    21601 taatacgtct gcaggaataa cagtaacaga tttttttata acttcaaatg tagatggtga
    21661 agatattata aagataaatc cagctataaa gagtaaccca aatgaattaa agcttactgc
    21721 tgatgaagct tcaaaaattg ctaagttaaa ggatgaaaaa atagatattg gggtggctgg
    21781 tggaaaagta agtacaataa gtgaccacta taaagccttt gcagaatcaa tcggtttaga
    21841 ttctcaaaaa gtaaatcaag atgaagcaaa tcaacgtaaa attataaata atattgataa
    21901 ctcaagaatg agtgtttcag gtgtatcttt ggatgaagaa atgacagagc ttataaaaat
    21961 acaacgttca tatcaagcta gtgcaaaagt tatgtcaaca gctgtgcaac tactggatgt
    22021 tgtaataaat ggaataattt aatagaaggg ggaatttata atgagagtca gtacaggtat
    22081 gatgtctagc agctatctaa actcactaca agataatcta caaagattgg ataaggttaa
    22141 tagacaagtt aatacaacaa aagaaataaa caagctatca gataatccat ataaagcaat
    22201 aaagatatta aactcaaaaa gtgaaataaa gactatggag acttatgttg agaattgtaa
    22261 agatacaggg aattggttag aaactactga tactgcatta gatcagcttg gaaaattatt
    22321 atcagacata aagaaaactt tggtggcaag tggtgatggt gcatactcag atgatgaatt
    22381 aaagactctt agtaatgaaa ctaatgaaaa aatgaaagaa attgcaaatg ctttaaatgc
    22441 aacacatgaa gggaagtaca tattttcagg ttcaaatacg ggggtaccac ctgttgaatg
    22501 tatagataat gctgatggtt cagtgagttt aaagtttaat tctagtctaa atcttaataa
    22561 attaaatgac tctttgagta tggatatagc tcaaggaata agtgtagatt ataacgttaa
    22621 attgagtagc cttggatttg acccaacaaa aactgaccca tttgaagagt taaataacat
    22681 atcaaaaaaa ttagcaaatc cagatgctga tgctataaaa gagcttacaa caacttgttt
    22741 gggcgatatg gaacaactaa tagaaaatac agtaaatgtt aggtctatat atgggacaaa
    22801 agcaaataca gtagaggcta tgaaggaaaa aaacgatgat agtttgatac agttaaagga
    22861 tattttgtca caaaatgaag aaatagatta tggtgaaaaa cttgttcaat taaaggcagc
    22921 agagttaact tatcaagctt cactacaaac aggaggaaag ttatttaatg tatctatatt
    22981 agattacata taataaaata acgcagatat gatgaaggtt acattaaaaa aaggtatatt
    23041 aggttttgaa aatttaaaag aatatgagct tttagatata gaagataatg attatttaaa
    23101 agaatttaat tctactgaag aagaaggtat aggatttgtt gttgtatctc catttgagat
    23161 tatcaatgaa tatgaaatag ttttaaatca ggaaacaata gaaaaactag aagtgaaatc
    23221 tccaaaggat gttgtattat ttaatataat tactcttggt cagacatttg aagaatcaac
    23281 tgtgaacatg aaagctccta tagtgataaa tataaaaact aattttggaa tgcaaataat
    23341 tttacaggat gataaatatt caataaggca tccattattg agaggtgata gtggatgcta
    23401 gtaatttcaa gaaaaaaaga tgaagcagta cttataggag aaagcataga agtaaaaatt
    23461 gtaggggtag atggaaacaa tgtgaaacta gctatatcgg cgcctaacaa tataagtata
    23521 ttaagaaaag aaatatacga aaaagtaaag agtgagaata taaaagctac aaataaaaat
    23581 ataaaaattt taaagtcatt aaaataataa gcttggagga agtaatatat gtatggagaa
    23641 aatccttata attcttataa acaaaatgct gtttttatgg catcaaagga acaattgtta
    23701 cttatgcttg ttgatggagc agtaaaatat accaaaatag ccagagcagc tatcttagat
    23761 aaaaatacac agaaagcgca tagagaactt gtaagagttc aggatatatt tacagaacta
    23821 atggttacat tagaccaaaa tgcaggacaa tgggcaaagg atatgtacaa agtttatgat
    23881 tttgtaagat atgaactttc aagagccaat attagaaaag acatccaggt aatagataat
    23941 gtgttacctg taatagaaca aattaaagat acatggcatg aagctgataa aaaaagtaaa
    24001 gaagaaagaa gtaggtacaa ataatggaat taaatttagc tgaattagat aagttatcaa
    24061 aagaggaatt actattgatg cttgtagatg gcacagtaaa atataccaat atatccaaag
    24121 aagctctttt aaataacgac tatttgaaag cacataatga acttgtaaga gttcaaaata
    24181 tatttacaga actaatgact acattagacc aaaatgcagg acaatgggca aaggatatgt
    24241 ataaagttta tgaatttata aaatctgaat tagcaatagc tgatgaaaat aaagatatta
    24301 aaataattga tgatatattg ccaatagtaa aacaaattag agatacatgg catgaagttt
    24361 acaatcaact aaaaatataa ttagatggag ggataaaggt atgtcaagta taagtcctat
    24421 aagagttaca ggtctttcag gaaattttga tatggaaggc ataatcgaag ctagtatgat
    24481 tagagacaag gaaaaagttg ataaagcaaa acaagaacaa caaatcgtta aatggaagca
    24541 agaaatatat agaaatgtta tacaagaatc aaaagatctt tatgataaat atctaagcat
    24601 aaattctcct aatagtatag taagtgaaaa agcatactct tctacaagaa taaccagttc
    24661 tgatgaaagt attatagtag caaaaggttc agctggtgca gaaaaaataa attatcaatt
    24721 tgcagtttct caaatggctg aaccagcaaa atttactatt aaattaaatt caagtgaacc
    24781 tattgttcga cagttccctc caaatgccag tggagctagt tctttaacta taggagatgt
    24841 aaatatacca atatctgaac aagatactac aagtactatt gtaagtaaga taaactccct
    24901 ttgcgcagat aatgatataa aggcttctta tagtgagatg acaggtgaat tgattatttc
    24961 aagaaaacag actggttcgt catcagacat taatttaaga gtaattggaa atgacaattt
    25021 agctcagcaa attgctaatg ataatggtat cacatttata aatgatgctg gtggaaacaa
    25081 atttgcaaat gtatatggaa agaatctaga agctgatgta actgatgaac atggaagagt
    25141 aactcatata agtaaagaac aaaattcatt taatatagat aatattgact ataatgtaaa
    25201 ttcaaaagga actgcaaagt tgacttctgt aactgatact gaagaagctg ttaaaaatat
    25261 gcaagcattt gtggatgatt ataataaact gatggacaag gtctatggtt tagttactac
    25321 taaaaaatca aaagattatc cacctcttac agatgcccaa aaagaagata tgacaactga
    25381 agaaatagaa aaatgggaaa agaaagctaa agaaggtata cttagaaatg atgatgagtt
    25441 aagagctttt gttgaagata ttcagtctgc attttttgga gatggaaaaa atattattgc
    25501 attaagaaaa ctaggtatca atgaaagcga aaattacaat aaaaaaggtc aaatatcatt
    25561 taatgcagat actttttcaa aggctcttat agatgatagt gataaggtat acaaaacact
    25621 agcaggttat tcttcgaatt atgatgataa gggaatgttt gaaaagctaa aagatattgt
    25681 atatgaatat tctggaagtt caacttctaa acttcctaaa aaagcaggta tagaaaaaac
    25741 tgcttctgct agtgaaaatg tatattcaaa acaaattgca gagcaagaaa gaaatataag
    25801 caggttagtt gaaaaaatga atgataaaga gaaaagactt tatgctaaat attcagcctt
    25861 agaatctttg ttgaatcagt attcttccca aatgaattat ttctcacaag cacagggtaa
    25921 ttaattatgg ataaattaaa agaaaaatta aatttatata aagatatatc tttacaaatt
    25981 ataaatttga ttgaaaagga agaatatata aatataagta gtaagttagg tgaaagacaa
    26041 gagattataa atagtgtaag tgaaattgat agaaatgatt ttatacagct ttataataga
    26101 atggaattaa ttgaaattga tagtaggata agagatattt tacaaggaca attattagaa
    26161 gtaaaaaaag aattacatga gtataagctt actaaacaag tgaacacaat gtattataac
    26221 ttaaatagag aaaaagtaaa tatttttaat aaaaaagtat aaagttatgt accatcttgt
    26281 ccgattatat aaatgaagaa ttaataaaaa agattaaaag tagaaatgac aaggatgtca
    26341 actatactaa ggagggtaaa ataatgagag ttaatacaaa tgtaagtgct ttggtagcaa
    26401 ataaccaaat gggaagaaac gtaaatgcac aaagtaagtc tatggagaag ctatcttctg
    26461 gtgttagaat taagagagct gctgacgatg ctgctgggct tgctatatct gagaaaatga
    26521 gagctcaaat aaaaggttta gaccaagcag gaagaaacgt tcaagatggt atatctgttg
    26581 tacaaacagc agaaggtgca ttagaagaaa ctggtaacat actacaaaga atgagaactt
    26641 tatcattaca atcttcaaat gaaactaata ctgctgaaga aagacaaaag gtagctgatg
    26701 agttattaca attaaaagat gaagttgaaa gaatatcaag ctcaattgag tttaatggta
    26761 agaaattact tgatggaagt tctacagaaa taagattaca agttggagca aactttggaa
    26821 caaatgttgc aggaacaact aacaacaaca atgaaataaa agttgctcta gtaaatactt
    26881 caagtataat gagtaaagca ggtataacaa gttctacaat agcaagcttg aatgtagatg
    26941 gagcttctgg aacagatgca gctaaacaaa tggtgtctag cttagatatg gctcttaaag
    27001 aattaaatac atcaagagca aaattagggg cacaacaaaa tagactagaa tcaactcaaa
    27061 acaacttaaa taatactata gaaaatgtta cagcagctga atcaagaata agagatacag
    27121 atgttgcttc agaaatggtt aacttatcta aaatgaatat attagttcaa gcatcacagt
    27181 caatgcttgc tcaagctaat caacaaccac aaggagtttt acaattatta ggataaaata
    27241 attttgtata ttggatatag aagaaagggt aaggctttgc tttactcctt tcttttttta
    27301 caaatatact tttgaaagga aaatttatat gttacttagt atagttatga ttgttaaaaa
    27361 tgaagaaaaa atacttgaaa aaactttaaa atcattaacc acattaagaa attctataga
    27421 aagtgaactt ataatagtcg atacaggttc tacagatgat actataaata tatctaggaa
    27481 atacacggaa aatgtgtact ttcataattg gaataatgat ttttctagta tgagaaatat
    27541 atcaatatct tatgccaagg gcgaatggtt acttatatta gatgcagatg aaatattaat
    27601 tgattcttca actattgtaa aatttttcaa ggacggtctt gataaaaaat ttaattctgc
    27661 ttcaatacaa ttaaaaaatc tttactcata cgataaaaaa ttatatggat attgttcggt
    27721 gcttagactt tttaaaaacg ttgattttag ataccatggt aaagtacatg aacaaccaat
    27781 atacaaaaat cctatattta ataatgttgc tgattttgaa cattatggat atttgtttga
    27841 agatgaagaa ataagattaa ataaggtgaa aagaaatgaa aaactattat ttcaagagtt
    27901 aaaagagaat gataattctc catatacaaa ctatcaattg gggaaaaatt ttattatatt
    27961 aggaaaatat caggaggctt tatactatct tgagaaatct tatgaattat attctaaact
    28021 agaatcggca cctggttact tgataacaag ccttgtaaaa acatatttat atttaggaaa
    28081 acataagaag tgtgaaaaat tgtgcttaaa gtatattaag aaagacatga ataatattga
    28141 tatatattat tatattgcac aagcacaagt agatttagga aagtatgaaa atagtataga
    28201 ttcgtataag agatatattt acttgttaga taattatgaa ataagtacac aagcaaatag
    28261 tttattttca gacactgata ctgtagggct tagagatgag gctattatta cactgataaa
    28321 gatttattat aagcttgaaa aatatgagtt tgtaatttca gagtacaata acattgaaga
    28381 tgtggaaaag aaaaagaatg tgtactttag cttatttatg tccctatata aattgaatag
    28441 atttgaagat ataaaaaatt attataaaga agtttcaaat tctaaaattg aaaaaaatag
    28501 tttttataga aatatagaag aagttataaa taatattaaa gaggatgaaa aagagtatgt
    28561 atataaaatc ctttgtgaca ttgagggtaa ttatggcatt ttaaatcaaa taaggataaa
    28621 taaatgtgta tctatagata aatgtaaaga aatactcaat gaagaaaagg aaataattta
    28681 tgcatatatt ataaaaatag cttttgaaga gaagattgat ttactagata ttttttatga
    28741 aatggaatat gtatggatag agaaatatct aaaatatctt ttagcattag aaagaagttt
    28801 taatttagta ctatataagt acataattag tcgtcaaaat acatcagata tggaaaagat
    28861 aagagtatat aaagctatat ctaaagtagt tttagaaagt ataagcttaa gtgatgaaaa
    28921 atataaggag attttttatt tttatataat gtattcttat aagtatataa gatacatata
    28981 tagcaattta agtgattttg aattaaaaaa atttgtttgc aatgatttag ataagttcac
    29041 tatagaattt aagcatctac ttgacattaa aaataaagta aataatgcta atgaaaaatt
    29101 agagtatata catagtatga ggaaattact aaatgagtat cctttttata ataaaataat
    29161 aaaaatactt atatgtgaat tagaagaaaa tataaaagaa agtgaagaat ttaaggattt
    29221 aaaagatagt tttattatta gtatagaaaa tatgattgaa actggcaaaa taaatgatgc
    29281 gaaattattg gtagatgact attcaaaaac atttgtggat gatataaaga ttttaaatat
    29341 aaagggaatt ttatacatgc ttgaaaataa gcttgataaa gctgatttta tgttaaaaaa
    29401 ggcattatca ttagatgtag aaaatgaaga tactatatat aatatagaat acttaaaaag
    29461 cttaagataa gtcaaaaata ggagaattga agaatgaata taccaatagt ggttaatgaa
    29521 aaatctaaag atataataaa agattggcaa tatacgtgta caaacgaaga tataaaattt
    29581 acaagcataa taatattgac atataatcaa atagaatata ctaaattatg tattgaaagt
    29641 attaggaaat ttaccccaaa gaataaatat gaaataataa taattgacaa taactcttct
    29701 gatggaacag ttgagtggtt aaagagacaa tctgatataa aatctgtgta taataacaaa
    29761 aacttaggat ttccaaaagg atgcaatcaa ggtattgaat tagctactgg tgaaaacata
    29821 ttgttgttaa ataatgatgt aatagttact ccaaattggc tctataattt gaataaagct
    29881 ttatggtctc aagataatat aggtgctgta ggacctatta caaatgcatg ttcatattat
    29941 cagcaaattg atgttgatta taagtcaatt gaggacatgt ttatatttgc acacaaaata
    30001 aataaatcta gtattaacct atggaaatat agattaaagt tagttggatt ttgcatgtta
    30061 ataaaaaaaa ctgttctgga taatgtaggg gttttagatg aattattcac acctggaaat
    30121 tttgaagatg atgatttatc ttttaggatg atagagtcag gatataagtt attattatgt
    30181 caggatactt ttatacacca ttttggaagt gtgtctttta aagaaaatcg taataaatat
    30241 acggatataa tgtatattaa tagaagaaaa tttgaaacta agtggggatt taatccagaa
    30301 tatagtggaa tgataagaac agatttgatt tctaaaatag atgatagttt ggaggcaaat
    30361 attaatgttt tagaaatagg ctgtggtata ggggctactc ttttagaaat aaaaaatata
    30421 tataaaaatg catcaatata tggaatagaa attagtgagt cagcaggtaa acttgcaaag
    30481 tatagtgcag atgtacttat agcagatata gaaaaagtaa aattggatta taaaaaagat
    30541 ttttttgatt atataatatt gggagatata cttgaacatt tgattgatcc ttggaagata
    30601 gtcaatgaat tgaaacaata tctaaagaag gatggttatc tggtatctag tataccaaat
    30661 attatgcatg tttctgtttt aagaaatctt gtgttaggta attttacata tgaagattca
    30721 ggaattttgg acaagactca cttaaggttt tttacattaa atgagataac aaaaatgttt
    30781 aatgatagta attacataat aaatagtatt acagctacta gtatgccact ttcggaaatt
    30841 gataatagct tcattgatac aatatgtaag gaaagctgta aagaaatgag acaacagtac
    30901 gaatcttatc aatatatagt aaaagcctct aaaatcctag atactaaaag atattctagt
    30961 attagtatgg ttaatttaaa atacgcttta atgagaattg ataatgaatt agatgtagat
    31021 agtaatttaa gttatatatt tgataattat aatataactg aaccatgttt tgttgatgat
    31081 attgaatatc taattgatac atttgtgata aataaagcaa ctctattaaa tagattagga
    31141 gttgaggcat ttaacagagg tctaggagat tttagtataa acatgtttat gacagtatta
    31201 gagatggata gagatgatat tgactcaata tataatataa caagtgtatt atgtgaatta
    31261 gaagaatttg atactgctta taatttaatt aaaaatagta gcgaaaaagt acagagtgaa
    31321 agtgatatac aagagatatt ttgttttatt gaggggaaga aatatgaata atgataagat
    31381 atgttttata acctgtgtaa atgatgaaag gctttatgaa gaatgtcttg tatatataaa
    31441 tagcctagac attcctaaaa actttagtat agaaacagta gctttaagag gagccgattc
    31501 tattgcctct gcttataata aagctatgag agaaacagat tctaagtata aggtatactt
    31561 acatcaagat acttttataa ttaataaaaa tttcatacat gatattttag agatatttaa
    31621 aaaaaataca gatgtcggaa tgattggtgt agctggagta aaagatatgc ctgtgaatgg
    31681 aatttggtgg gattctgata aaaaagcagg gaaagtatat gatagtcata caggtaaaat
    31741 ggatatttat gaatttagta actttgaaga atgttttaat gaagttatgg ctatagatgg
    31801 attaattatg attactcaat atgatgtatt ttggagagag gataagtttg atgggtggca
    31861 tttttatgat ttgtcacaga gtatggaatt tagacaaaat aaatacaaag ttattgtacc
    31921 aaaacaaaat aagccttggt gtatgcatga ttctggagta gcaaatataa ataatggata
    31981 tgatgaatat aggataaaat ttgtaaaaga gtacataaat cttgatttat atagagaaaa
    32041 tttttatgaa tttgataaga agaaagcaag tgccatactt aagagtaata agcatgtaat
    32101 ggattgtatg aaagaggagc ttacagaaca attaagatta aagaattaca aggatgtttt
    32161 aggtattgtt tctaaaattg ctcatttttc tgtttttaat catactggtt tgtattcttg
    32221 tgaagaatgt gagagagcat tgctagaatg tgcaaataat ttaccagaaa tagaaaatac
    32281 gaaattattt acaaaaaaag atttaaaaag aagaaaagta ttacatgttt taagtgaagg
    32341 atattcaaca ggaggtcata caagactagt taaaaattgg attgaaattg acaaagactc
    32401 tgttcattca gttgtaacca catggcaatc agatacactg ccagactggt tattaaaagc
    32461 aatagatgat agtggtggcg aagttatatc tttggattta atttcagatg attatttaaa
    32521 aagagctatg gctttgagaa aaatagctta tgactgggct gatatagtta ttttatatgt
    32581 tcatatgtgg gatacaatac ctgttgttgc ttttggagtt gatgggaaaa tacctatttt
    32641 acatgttaat cactatgata gtactttttg gttagggaca agtattgcag atattgtcat
    32701 tgattttagc gaagctagtc aattaattac attagataaa agaggcatag ataaatctga
    32761 aatattacca atgccattaa aagaaaaaga agtattttca aaatctgaag ttagaaaacg
    32821 atataatttg gaggatgatg tgacaataat attgactatt gctagtgaaa gaaaatacaa
    32881 tagtgtaaat gatattaatt actttaaaat tgctaaaaca ttgattgaaa atacagataa
    32941 tacaattatt attgttgtag gagttgatac agagaatctt tattggaaaa ctttaagtaa
    33001 cgttacagat aatagagtta tatgttttgg aacaacagca aatatagacg atttttacaa
    33061 gatttcggat atatatatgg agtctttcat ggtaggaagt catacttcaa aactagatgc
    33121 aattttatat gatttaattc ctgttaagtt taaaaatgaa gtttcaccaa tttttacaaa
    33181 tatgtggaat tttatagata agtttgatta taagaatata aaagaggtta tagatatgat
    33241 aaaaaggtac aatactagtg aatttgacag ggataagata aaagaaaaac aatcggaaat
    33301 aaaacatttt gttatagata aacactgtat tgaaataaaa aactatatag acaaaatata
    33361 taatgaagct aatcatcata aagttaagta taatttatat aaaaatgatg aaatcgagga
    33421 ctatcagctt tttgtagcat tatatggcta tatggtaaaa aataaaaaca tgtcataggt
    33481 ggtaaaatga acaatattca tatcaataaa tttgaaaaaa gctgtgaaaa aaactgggat
    33541 tattttgtag aaaataaatc tataaatggt acatttctgc aaactagaaa tttccttaat
    33601 tatcatgagg agggaaaatt cactgaccac tcattaataa tatgtaaagg tgaagaaata
    33661 ctagcagtcg tacctgcatg tgaaacttat gaagatggtg aaagaatatt tttttctcat
    33721 ttagggagta cttttggtgg tattataata agaagtggtt ttaatgatat taggcatgta
    33781 aattccatta caaataagtt agaaatatat ttacgggaac aaaatttcga taaagtatat
    33841 ttaaaaaata catcaagaat attttgtaaa gaggatactt cattactaga atatttttta
    33901 tttaagaata attacatgtt ttatgatgaa ttaagtatgt ttttagaatt aagtaagtat
    33961 aaagaagata tattagccaa ttttaaatac agtaaaagaa gagattttaa atattctttg
    34021 aagaataatc ttacctttaa aagactgtat agtgatgaag atatagtttg tttttttaat
    34081 ttactttcta attgtttaga tagtaaagga gctaaagtaa tacattcagt agaagaactt
    34141 ttggagttta aaaataatag attaaaagat attgtagaat tttatgcagt atatattgat
    34201 gacattatga tttgtgggag catggtattt aactttcaag aaagagttta tcatactcaa
    34261 tatctagcat caaattcgac atataataaa tattatccaa tgatattttt atactataat
    34321 ctaataaaag atgctttaga gagaaatttt aagtatcttt cttttggaat tagcactcta
    34381 aatagaggca aatacttaga cgagggttta gctacattta aagaaggttt tggttcaagt
    34441 gcaatttgta acagaacata ctataaaaat ataaataagt gagaatcatg ttttatagag
    34501 tttttagagt atagtaaata tctagtactc taatattaca taaaaataat tagtttataa
    34561 agaaggtttg tatatgaaaa gattaatgat tttaggctca attaagtatt ttgagaatat
    34621 tgttatatca gctaaaaaag agggaatata tacaattgtt tgtgataata gaattgatac
    34681 tcctgcgaaa aagatttgtg atgaagcaat agatgttgat gtatttgatt ttgataaaat
    34741 aaaaagtata gctatagata aaaagataga tggaatttta actggattta cagattcttt
    34801 aatgaaacca tatgtttata ttgcaaatga actaaattta ccatgtgtga tttcttgcaa
    34861 tcaacttgaa tctgtaacta acaaggctat tatgaaaaaa tattttaaaa ataatgcaat
    34921 acctacaact gattattgta ttattgaaag tctaaaagat ttagaaaaaa tacaaagatt
    34981 aaattttcca cttgtaataa aacctgttga tggttatggt tcaagaggtg tatattttgt
    35041 atcaaatata gaagaattaa tagaaaaatt tgaatattct aaggaagcct cacaagatgg
    35101 acaagtaata attgaggaat tttatgaaag tgaggaaata caagggctag cttgggttca
    35161 taatggagag tcacatgtat tttatattgg agatagagag cttgtaaaca tacatacagg
    35221 aagagctgga aaaccagata gattacttta tccatcaaag tattgttttc aatatgagga
    35281 ggaaataaaa tctatatatc aaaatataac acaggctttt gatataaaaa atggacctct
    35341 ttatgtacaa atgttagtgg gagcatatgg aataaaggta tctgaagtaa tgccaagatt
    35401 acctggaggt tgtgactata tggctatttc tcaaataaca gatttagaca taggaagttt
    35461 atttgcaaac tttagtgtga ataatgaagt aaattttgat gaaataaaga aatataatat
    35521 gcatctatca aaatgtgtat atgcattacc aatatacata agacctggga caataaaaaa
    35581 gataaataat atagataaaa tagaaaactt agattatgtc actcaatttc tattactagt
    35641 aaaagaagga gatacaatag aattatatga agatgagaga caggattgtg gaagagttta
    35701 tggaatagca aataatatat ttgatgcaaa tataaaaaag aaatgtattc atgaaatgat
    35761 agaaatactt gatgaaaata atgaaaatat gatagaaaat ttttaaataa gggagtatga
    35821 tagatatgaa gttaataact catgaacaaa ttatgtcatt aaacatttct cagaaacaag
    35881 gatatgagtg gataaaagaa tccttcttaa caaaaaaaga ttgtcaatta ccaccaaaaa
    35941 taagcatggt agaagaagga catgtatttt acaatgtaat gccatcccta aatcataatc
    36001 atatgattgg tggaataaaa atggttacaa gattgccagg gagaaatcca agtttaaact
    36061 cagagatatt tctatataat atggaagatg ctaaattaaa ggctattttg gatggtaatt
    36121 atattacagc ttttaggact gctgctgttg ctgccttggc tatcgataca tttgctaaaa
    36181 aagattttaa tactattgct attatgggtt taggtgtcac tgcttctgct ataatgaata
    36241 tgctttcata tactcttaaa gataaaaata taaatataaa gttacttaaa tataaagacc
    36301 aagcagagtc gtttgtaaaa aagtatgaaa aaaatgaaca atttagtttt gaaatatgtg
    36361 atacacatga agaacttatt gtagattcag atgtagttat ttctactgtg acatatacag
    36421 atgaatattt atcagaattt aaatggttta aaaaaggtgc tttattatta cctgtacatg
    36481 ttatgggatt tggaaatgtt gattatctat ttgataaagt atatttagat gattataatc
    36541 atttgaaaca tctagaaaat atagatagat ataaatattc ttgtgaattt tatgatgttt
    36601 taagtaaaca agctaaagga agagaaaatg atgatgagag aataatatct tacaatatag
    36661 gtttgtcaat acatgatata ttatttgcaa ataaaattta cgaattgtgt gaaacactaa
    36721 gctgtgaaga aatagaatta aaagaaccaa aagaaaaata ttggatatag tttatttcat
    36781 tcatatttac aatagtttat tgtaaatatg aatatgaagt aatatattgt tagaaaatta
    36841 gcatgaatag gatagataaa tttatggata aatataattt aattaggttc gtatctattg
    36901 gaaacgaata tataggaaat ttagttgcat tagaatcaaa taaagtaata ccttttgata
    36961 taaagagagt ttattacata tatgatgtac caaacaatgt aaagagagga tttcatgcac
    37021 acaaaaactt ggaacaagta ctagtttgcc taaatggaag tgtgaagata aaatgttatg
    37081 atggtgtaaa agagactata tttaatttac ataaaaatga tgttggatta tatataggaa
    37141 cgggagtgtg gcatgagatg tttgattttg atgaaaaaac tgttttaatt tctatagcat
    37201 ctgaacatta taatgaagaa gattatatta gagactataa agaattttta aagtatttaa
    37261 ataatatgta gttattatac aattagtgat gtattttctt aattaaataa atttaagata
    37321 gccacataga gaatagatag attaggatgt gaatttattg ttggttaaat ttaataattt
    37381 attaaaacag ttccaaactc ataaagaaga atatgaacag aagattaagg atgtaatgga
    37441 aagtggatat tatatccttg gaaatgaagt aaagcatttt gaagaagaat ttgctaacta
    37501 tgtaggtagc aaatattgtg ttggtttagc cagtggttta gatgcactga taattgcttt
    37561 tagagcatta ggaataagca aaggtgatga agtaatcgtg caatcaaata catatattgc
    37621 tagtgttatg ggaatcagta taaatggagc aacaccagta tttgtagaac caaatgaata
    37681 ttataatata gattcatcta agatagaaga aaagataaat agcaaaacaa aagctatatt
    37741 agtagtgcat ttatatggtc aagcaagtaa tatgaaagat atacaagaat tatgtgataa
    37801 gtataacttg tatttaattg aagattgtgc tcaatctcat ggagctaaat atgatggaaa
    37861 aatgacagga acatttggtg atataggttg ttttagtttt tatccaagta aaaatttggg
    37921 tgcatttgga gatgcaggag ctatagtaac tagtaatgag gaaatagctg ataaagtgaa
    37981 aattcttaga aactatggct cagaaaagcg atattataat aaatttgtcg gatataattc
    38041 aagattggac gaaattcagg caggtttatt aagagtaaaa cttaaatatc taaatgaaat
    38101 tgaaattgaa aaatcaaaaa tcgtagatag atatcttaat gaaattaata atcccaaagt
    38161 catacttcca aagatagaaa ataattgtac tcatgtatgg catttatttg ttttacaagt
    38221 tgaaaaacga gatacattta tggaatactt aaagaaaaat ggtatagagt ctataataca
    38281 ttatccgata ccaccacatc tatctgaagc atatgcttat ttgggatata aaaaggggag
    38341 ttttaatata gctgagaact attcagataa agttgttagt atacctttat ttattggtat
    38401 ggaagatgaa gaagttagtt atataattaa aattataaat
//
LOCUS       DAEQAF010000030        38241 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.031, whole genome shotgun sequence.
ACCESSION   DAEQAF010000030 DAEQAF010000000
VERSION     DAEQAF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38241
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.031"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(46..675)
                     /locus_tag="KRN00_001620"
     CDS             complement(46..675)
                     /locus_tag="KRN00_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827487.1"
                     /translation="MFEKKKKELFPWKISALILVGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            878..1201
                     /locus_tag="KRN00_001621"
     CDS             878..1201
                     /locus_tag="KRN00_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH1827488.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            1469..2323
                     /locus_tag="KRN00_001622"
     CDS             1469..2323
                     /locus_tag="KRN00_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827489.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(2509..3945)
                     /locus_tag="KRN00_001623"
     CDS             complement(2509..3945)
                     /locus_tag="KRN00_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBH1827490.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNSGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISRGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(4016..5398)
                     /locus_tag="KRN00_001624"
     CDS             complement(4016..5398)
                     /locus_tag="KRN00_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1827491.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            complement(5534..6439)
                     /gene="garR"
                     /locus_tag="KRN00_001625"
     CDS             complement(5534..6439)
                     /gene="garR"
                     /locus_tag="KRN00_001625"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBH1827492.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHDN"
     gene            6835..7506
                     /locus_tag="KRN00_001626"
     CDS             6835..7506
                     /locus_tag="KRN00_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1827493.1"
                     /translation="MATFKRLQEQAYDYLKELILSGEMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEP
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            7609..8157
                     /locus_tag="KRN00_001627"
     CDS             7609..8157
                     /locus_tag="KRN00_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827494.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            8419..8727
                     /locus_tag="KRN00_001628"
     CDS             8419..8727
                     /locus_tag="KRN00_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827495.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(8889..10679)
                     /locus_tag="KRN00_001629"
     CDS             complement(8889..10679)
                     /locus_tag="KRN00_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827496.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(10679..12406)
                     /locus_tag="KRN00_001630"
     CDS             complement(10679..12406)
                     /locus_tag="KRN00_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827497.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RAKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            complement(12651..12917)
                     /locus_tag="KRN00_001631"
     CDS             complement(12651..12917)
                     /locus_tag="KRN00_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBH1827498.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            13215..14327
                     /locus_tag="KRN00_001632"
     CDS             13215..14327
                     /locus_tag="KRN00_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBH1827499.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            complement(14691..15200)
                     /locus_tag="KRN00_001633"
     CDS             complement(14691..15200)
                     /locus_tag="KRN00_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH1827500.1"
                     /translation="MSQQNTGNAIVNSKPKKTAVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(15202..15849)
                     /locus_tag="KRN00_001634"
     CDS             complement(15202..15849)
                     /locus_tag="KRN00_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827501.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            complement(15863..17035)
                     /locus_tag="KRN00_001635"
     CDS             complement(15863..17035)
                     /locus_tag="KRN00_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1827502.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAK
                     RLKFEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            17302..18678
                     /locus_tag="KRN00_001636"
     CDS             17302..18678
                     /locus_tag="KRN00_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827503.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            complement(18928..19761)
                     /locus_tag="KRN00_001637"
     CDS             complement(18928..19761)
                     /locus_tag="KRN00_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1827504.1"
                     /translation="MTIKEVEEKTGLTRSNIRFYENENLIKPLRNERNGYREYSDENV
                     EDIKKIAYLRTLGITIDDIRNIILQKVSLVEVVEKQEKVLETKISDLENAKTMCNKML
                     ESDELSYLNLKVEQYITELPEYWNKNKPVFKLDSVSFLYIWGGKITWGIITIACLLIA
                     ITVFPKLPPQIPIQWNNGVANYVDKKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSD
                     TIADYLTNFMCFVALSIEIFSILFIYNIARHVTIIIFIDILVFIALLIIGVYKLFKKY
                     N"
     gene            complement(20089..20619)
                     /locus_tag="KRN00_001638"
     CDS             complement(20089..20619)
                     /locus_tag="KRN00_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1827505.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIKEEKDIKDVNELVDYGIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
     gene            complement(20707..21801)
                     /locus_tag="KRN00_001639"
     CDS             complement(20707..21801)
                     /locus_tag="KRN00_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBH1827506.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDIMKMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLFSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            complement(21803..22249)
                     /locus_tag="KRN00_001640"
     CDS             complement(21803..22249)
                     /locus_tag="KRN00_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1827507.1"
                     /translation="MDFKNLQYESLSYIICNLQKNFKLYCEKCLKPYKLTNGLYFYLI
                     YINKNRNCSLNDVSTEFEVDKAHTTRTISRLEQDGYIEKIQNPNDSRAFQLRVTDKGE
                     EVLGDIKNIFSKWDNHIKKEFSDTEYKELVKNLHVVKDIKTAVEEE"
     gene            22555..23745
                     /locus_tag="KRN00_001641"
     CDS             22555..23745
                     /locus_tag="KRN00_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1827508.1"
                     /translation="MISNKMQTLVANSSVIRAMFEEGKKLSDIYGEENVFDFSIGNPS
                     VEPPETIKAVINDILNEESPNLVHGYMNNSGYEDVRDAIAEHINKKDGLNLTRENLIM
                     TCGAAGGLNIILKTLLNPGDEVIAFAPYFGEYKNYTENYDGKLIEVPTNIETFEPDLD
                     ALKNAITPKTRALIINTPNNPTGVIYSEELLKNLGELLDSKQKEFNTSIYLISDEPYR
                     EIIYDGAKVPCVLKYYRNSFIGYSYSKSLSLPGERIGYIVANGQMDDFDDVMSSLNVA
                     NRILGFVNAPSLFQRVIARSLDAEVDVNIYKKNFDLLYNSLIDMGYSCVKPNGTFYLF
                     PKAPIEDDKKFCNDAKQFNLLLVPGSSFGCPGHFRVSYCVSYDKVKSSLPAFEKLAKL
                     YNLK"
     gene            23915..24877
                     /locus_tag="KRN00_001642"
     CDS             23915..24877
                     /locus_tag="KRN00_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBH1827509.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(24999..25661)
                     /gene="zmp1"
                     /locus_tag="KRN00_001643"
     CDS             complement(24999..25661)
                     /gene="zmp1"
                     /locus_tag="KRN00_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBH1827510.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     regulatory      complement(25761..25846)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(26031..28949)
                     /locus_tag="KRN00_001644"
     CDS             complement(26031..28949)
                     /locus_tag="KRN00_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBH1827511.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIPEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGTLKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINDSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYKVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSKIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSVLEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDANFTNVKVGETIRNVAQINGSSPPGVETTKQGYTFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSVKKPGTYYLVEIMAPRGY
                     EKLKDKVKVEIGNEDIGKIVDIGNIENLKQENPPVNPPIPPDTDEPMVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPVPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVNPSVSEEKNNKVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      complement(29067..29152)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(29279..30457)
                     /locus_tag="KRN00_001645"
     CDS             complement(29279..30457)
                     /locus_tag="KRN00_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1827512.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     gene            30832..31017
                     /locus_tag="KRN00_001646"
     CDS             30832..31017
                     /locus_tag="KRN00_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBH1827513.1"
                     /translation="MFFISYIYTKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            complement(31082..33856)
                     /locus_tag="KRN00_001647"
     CDS             complement(31082..33856)
                     /locus_tag="KRN00_001647"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1827514.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSVLSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(34028..35284)
                     /locus_tag="KRN00_001648"
     CDS             complement(34028..35284)
                     /locus_tag="KRN00_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBH1827515.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGVRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            complement(35356..36858)
                     /locus_tag="KRN00_001649"
     CDS             complement(35356..36858)
                     /locus_tag="KRN00_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1827516.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            complement(36949..38139)
                     /locus_tag="KRN00_001650"
     CDS             complement(36949..38139)
                     /locus_tag="KRN00_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1827517.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHMSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
BASE COUNT        12669 a         6410 c         4539 g        14623 t
ORIGIN      
        1 tattaactta cttagtattt aacttgaaat aatattaatt tactattaac ttgcaaagtc
       61 ttctaatctt gaataggcct cttcttcagt atccataact acaccttttt tgatttcatc
      121 ttgaactgtt ttaggaagtg aatctactct tatttttgtt ttttctacta atgttttact
      181 tccactatca tcatatttat atagtgctat atttccatta tcattttcaa tagtatattt
      241 accttttata gtaacatcca ttgcttgtac atctttatta tcactatatt tagattctac
      301 caatatgatt tcatttttat ccatactctt tattttttta gttggatatt cttttttaaa
      361 atatgatact atttctgact tcgtcttatc taataatgac tctggaacta ttcctgccat
      421 tgtaagtgtt ctcttatagt tagtttcatt ttcgccttca ctttgaagcc aaacttcaca
      481 atttttattt aatccaaaag cttcttttga cttttcattc atattcgcac tagtacttac
      541 aacttcacca gtttgaactc cattgtgttt taatcttgtc cctatataaa ctccgctact
      601 taatacaaat actccaacca gtattaaggc agatattttc caaggaaata attctttttt
      661 cttcttttca aacattgatt acgcctcctt tttctattat tttctccaag ctgtaagttt
      721 ttatacaatt taggtaaatt ttagaagaaa atatatttat atttcaaatt actctaagaa
      781 tagatatttt ctaaaaggta gttttctctt aatggttata ttcttgtaat tatatggaca
      841 taatttataa taaataatcg tttaggaggt aataactttg gaaagaataa actgtaatgt
      901 aattaactgt tcacataaca acagccatat atgttatgca gataaaattt ttataaatgg
      961 tgaaaaagct cacaatgata gacatacttg ttgtagttca tttttagatg aatctattta
     1021 tagtaattta tctagcaacg ttaataatag aaattgtgag gaattagttt gtactgtaaa
     1081 aaattgtaaa tacaacaaag atggtagctt atgtacactt gataatatat tggttgctcc
     1141 tgaaactgat agagtaaacc tttatattga aacatgttgc tctagtttcg aatgtaaata
     1201 gtcatagtat aaatataagg gtgtcaaatg taattaaact aacatagtgt agagtatcta
     1261 caactattag tttgattata cttgacaccc ttatttattt taaataaaat ttcattatta
     1321 taaccatgtt tataatgttc taactgtaat taaatttgat aaatttctat aaattggtat
     1381 aatcaatatg taaattgaat ttagcaaatt aatcataaaa ataaaatatc gagtatatag
     1441 tgttatacta actagaaatg aggtgcttat gagtacattt tatattcaat ttctttattt
     1501 tgtaatttat agctttatag gatggtgttg tgaaactaca tattgttcag ttttacaaaa
     1561 acaatttgta aatagaggtt ttttaaatgg tccattttgc cctatatatg gatttggagc
     1621 attagcaata gttgctacct tgactccttt tgtacacaat attcctttgt tatttttgtt
     1681 tagtataatt ataactagca taatggagta ttgtacgagc tttattttag aaaaaatatt
     1741 taatatgact tggtgggatt attctaaaca taaatttaat attcatggaa gagtttgtct
     1801 ggaaaattca cttatgtttg gtgtattatc attgattgta atgcttatag tacatcctat
     1861 tgtggttgac tttattaact ctatctccaa aaatgtgcta tttatatttg ctatatctat
     1921 agaaatttat tttgttttag atttagttat cacagtccat acaattttac aattaaatgg
     1981 taagttaaag caaatcaatc ttataattaa ggaattaaaa gataagaagg aatactacaa
     2041 acttattaca caagaaacta tagaaaacaa acttgaatct ttagttgaaa atagactgga
     2101 tactttggaa gataggtttg aaatacttaa ggaaaaagaa aattatcgct atgctaaaaa
     2161 tcgtattgat gagctaaaaa ataaacttaa tactttgctg tctaaccaca aattacttca
     2221 tagacgtata atcaaagcat tccccaacat aagctctaat aagcatacag atattttaaa
     2281 taaaatcaaa gaaaatatta aatcaattaa aaaagataaa taataaaata aacacataag
     2341 ttaaataata aaaatactaa tacataagat taaggtttag aatatttttt gtaaaatact
     2401 ctaaacccta attaatatac tattattttt aatcttaatt tataatttta gtttatttta
     2461 attttaactc agtaaattta agcgtttaaa cttcaataca ctaatatact accccatcaa
     2521 tatctcaact gattctctaa gtgtgctaat ctctcccaca tttccaggga aaattatata
     2581 tggcatatta ggaaatttgc tttctttgcc tgtcatccat actggtatac caggttttat
     2641 ctgtcccatt actgtagctt tttttactct tagtgcttta gtaccaacat cactagaagt
     2701 aattccaccc ttagctataa taaaatttgg tcttacatta agcataccaa ttatactggt
     2761 aactgcatct gatatttcta cagaaatcat aagctgttta tctttatcat tcgtatccaa
     2821 gtcaaaacgc tctcgtctag tataaacagc aacagtttta cccctgctta ttttttcctc
     2881 tacaactttt ataactcttt ttacctcatt ttttagacca ttttcttgaa gaactaaatg
     2941 ttgattaaat tctataaatt ctatcggata tttacaattt ttaagttctt ctaactgttg
     3001 ggtagtctta ttcacatgtg aaccaacaag tataattcct ccattggtat taccttttga
     3061 tactaattca tccttagtaa gtagttcctt gtcactcact ccgccaagta cttttgttat
     3121 ggcagcagcg cttctaaaca taaattcctt accactattt actgctcgta taaacgcaat
     3181 tgtaaatacc tttacatcta cataatcggt tgcatttaca ataattttat tgaatccttc
     3241 agctttttta agtttttctg ttatagcttc aatatttagc tctctaagtt cttttgacga
     3301 aatatatatc atatcactag atttgtactt tccatttgtc ttttcttcac accactcacc
     3361 tatatcagat gatttatatc caaaagattt atcttttgca aattcagtca ttcctgctgg
     3421 tacaagtatt tctccttctt taacataatg tacattatct atagtaaacc taccaccttc
     3481 tttaaaaaat ggcattatta tttcaccctg aaataacttc cccgataatc tctctacttc
     3541 gctttttaat aaattagttt caagaggata atgtcctctc atagtagaat cactacgact
     3601 tatgattata aaatccttat taactttctt tgatacatcc acaatattct ttgaaatttc
     3661 tttatgtgct tttgtagttt gagcaacagt aaatcccctt gaattggtaa gtataaaaaa
     3721 catactattt ttctcattaa agccttgttc catactatcc ttatcccaat cagtataaac
     3781 agaaatatca tgaactgttt gtacacctgt tgggtcatca tctaatacaa caatttttct
     3841 atctaaatgc ttaagctcat ctgcaagaag tttatttaat ctatcctcat ctacttgttt
     3901 aaaagtatta agtatatcta tgctaattgg ttttacttct ctcatttaaa acgccccttt
     3961 atgtaatttg tatagtctaa atgtaattta tatgatataa acaatagttt gttatttata
     4021 gacctggaag tggtataatt ccatttataa cactaagcaa taaaaccatt ataaatgcta
     4081 caactccagc aatggttcct ccaattgtcc aagagtttaa agtatcttta actgataatc
     4141 cactaaatct tgaaagtacc cagaatccag aatcatttgg aagggagaaa ccaactcctc
     4201 cagcacatat agcaagccct actaaaactg gtgacattcc agttgccaaa attgtaggtc
     4261 ctaaaattga tgatgttgtt actaaggcta cagtagcaga accttgagaa attctaagca
     4321 aggcacttaa taagaatcca agcactacaa ctgatatact aagaccagac atagtatcaa
     4381 ctaagaagtt acctatacca cttgcattta taacactgcc aaacgcacca cctgaacctg
     4441 ttatcaataa tattagccct gctgaatcag cagcttcaat aactacatcg cccataggtt
     4501 tatttatgta tttctttaaa aatcctattg ccaccaatat tccaagaagt attgctatgt
     4561 ttttatctcc tataaatgca agtactccac tcattgtaga acctttttct aagaacatac
     4621 taaatacatt tgatataagt ataagaagta ttgggaacaa taaagaaaac atagaaattc
     4681 caaaacctgg tactttagaa gaatcatcat cttcaatttt tatgctatct tttccctgtt
     4741 ctaaattttt ttctctatca ttctcatcaa tagcataagc tggatatttt tcaaaacgtt
     4801 ttccataaat ccatccacct ataagagctg ctggaaaagc aacaattata gaataaagta
     4861 taaaactacc tacatttgca tttacatttg ctgcaactgc taaaggtcct ggtgtaggta
     4921 ttacaagtgc atgacctact atagtcccaa ctcctaaggc acatacaaaa accattagag
     4981 atttcttagt tactctcgaa acatacttaa ttataggcat cattataaca aaagctgcat
     5041 ccataaaaac tggaattgaa attaaaaaac ctgctgtagt tactgctaaa gcactgtttt
     5101 tttctccagt cttagctaac aacccctttg caatagattc tgttgctctt gattctgaaa
     5161 gaatatttcc aaatattatt ccaagtccaa ttacaatacc tatactacct aatgtatttc
     5221 caaatccagt cgatattgtg gttgatattt catttatagg cattctaacc ataaagcctg
     5281 taattataga tgttatcagt aatgccaaaa acggatttac tttaaattta ataatcgata
     5341 caagtaaaat tcctatagat ataacaaatg ctatcaaaag tccatatcct gtaatcataa
     5401 tctttacccc tttatcattc tactttatta tttatcaatt ttatttttct tttactatga
     5461 taacttaacc tcgctgtatt tatataatct aatcctaata atatgtattt aattatattg
     5521 atatatttaa atattaatta tcgtgttttt ttatttcaac acctgccaac ttttcaaaat
     5581 actgtgctat tccactatgg tcatcttcca aatgtccatg tacttttaat gtctgcataa
     5641 tttctaataa ttgacttgtc ataggtagtg gtacatctaa attgtgtgct gtttgcatta
     5701 cattcttaat atctttcaaa ttaatagata ttttcccacc tggtttaaaa tcacgattca
     5761 taatcattgg tatcttcgca tccaatattg tactaccagc taggcctcct cttattgcct
     5821 tatatacttt ttctgggtct gcacctgctt ttgctgcaag tacaaatgcc tcagaaactg
     5881 ctgctatcgt caaattaact attacttggt ttgtaagttt tgtaacactt ccactaccat
     5941 tatctccaat taaaatagat gagcttccca ttatattaaa aaatggctct actttcttat
     6001 aaatttcttc cttaccacca gccataaaag caagtgtacc atcaatcgct tttggctccc
     6061 ctccacttac tggtgagtct ataaattcta agcccatatc ttttaattta tttgcacaca
     6121 atatggattc tgtaggagta actgaactca tatcgactac tatacttcct tcttttaaag
     6181 tttttgccaa tccatccatc ccaaacaata tatcctgcac aatagttcca tttggaagga
     6241 ttgtaaatac aatatcacat tcttgaccca tttctaaaac acttgcgtat tttgctccac
     6301 atgatataag ttcatccaca gcagatttat taatgtcata caccaaaaga ttacatccat
     6361 cttttaataa attttttgcc attggctttc ccattattcc taatccaata aatcccaatt
     6421 tcattttata accctccata tcttcacatt tttgaaaacg ttttttatgt tttagagtat
     6481 actacatacc agtataccgg tcaatataaa atataaaagt atttatttta acaataaata
     6541 gtaattttta aagtcattta ttatatttag tcatcctata taagttttaa tacatactat
     6601 tgttttcaaa tataatatac tacttttaca gttttgtatt ttaactaatt tcaattagtt
     6661 ttaattaatc tgcctttaat gttaatcatg cttcacactt caataatttt ttatattttt
     6721 taatcttatc tgcaatttaa attgcaaaag attgacctta ttttcactat gttgtatgct
     6781 taaaattata taagtttttg tatttttata ttgtttaggg gggtattatt aagtatggct
     6841 acatttaaaa gattacaaga acaagcatat gactacttaa aagaattgat actatctgga
     6901 gaaatgatag aaaatgaaat atattctgaa acaaaacttg ctagtgaaat aggtatctct
     6961 agaacaccta taagagatgc tcttcaaaga cttagtcaag atggatttat agatataatt
     7021 ccaagcaaag gatttagaat ccatcaaatt acagcaaatg aaattgtaga gatattccaa
     7081 atacgctctg caatagaagg attttgtact tttttaatta caagtcaata caaagaacct
     7141 agagcagtag aaactataag taaattaaaa catcttttag ataaacaaaa agatatttta
     7201 ttaggtgata aaaatttaaa ctcatttgca gaatacgata cattatttca cacaactata
     7261 gtttcatatg ctcaaaatac tgaatttgac aaaatgttta acaattatat gtacagaata
     7321 aaaaaattag ctctcgattc attgtcacat gaaggaaggc ttgaaacaac attaaaagag
     7381 cacacagata tttttaataa tattgcaaat ggatgtattg aagatattta cagaactact
     7441 ctcattcata tggaaactcc taaatacatt aatttagaag atttttgtaa caataagtta
     7501 ttttagtatt atactttcat ttattaaaaa tatatctatc tcaaattaat ttcctaattt
     7561 ataaaaaata ttctataatt atattgtaac taatacttat tctaaggagt gatttttttg
     7621 aacgaagatg ttgtaactaa tgaaactatc gacaaagatt atgctattga agaagttcgt
     7681 atggcatgca aacattttgg tgatttatat ttttattttt ccaaagtgtt atttgaagag
     7741 tttggtgaag ataaaactag cgaaatatta agaaaagttt tatttgaaag gtctgaagaa
     7801 agagctattg ctatgagaga gagagctcat gaaaatggag atgaattaat cgcagacaat
     7861 attattagca caactgatgt tccatttcta ggatgggttc ctgaatttga agagttacat
     7921 tgcccctatg gagcttcttg gcttttaaga tttgaggaaa atccttggtt taaaaaattt
     7981 gcttctcttt actgtgatgt tacagatact actgtagctg aagtatttac aggagatacg
     8041 tcccataaaa taacaaaaaa cattctatgg ggagataaaa gttgtgaaag aatatatttc
     8101 catgatgaca aggtatctga aggtaaatat acttatggaa ataaaaactg taaataaata
     8161 atttaaattt tctatattca tatactatat tttgtacttt ttcatataaa tattataact
     8221 agtcttttat tttacttttg tttaacctaa agataattta cttttaatct atatgaatta
     8281 tcatataaat aatcagaaag ttatctttat aaattatagt tttagattta taatttataa
     8341 aatatttatg ttctttgtaa aattttttag aagcttctaa tgttatgcta taaaactatc
     8401 ttgagaaggg ctgattgaat gtttaataaa atatatgaaa agaaagaatt tatagttttt
     8461 caagttaaaa aaggttatgt agtttataat actagaaaga gttttgaaga aggtcataca
     8521 catttaaagc attttgaagc agcaaagaca gctattgatt tagcaataaa taaaaagatt
     8581 cctagaagca aagatggata ttatctgact agtttaattc gcataagtga tgatggttat
     8641 tacattgata agttaagcga attgttatat gttagagaac aaaaaggtaa aaaagaaaag
     8701 tactgtaatt ctggttatca gatgtaacaa gactagttgt gaattataag taccaatcat
     8761 aaataccttt agtcttaaaa tcaaagagta tcagtaaatc tataaaaaaa caacttactg
     8821 atactctttt taattatatg attaatattt gaatttgata caaaatttta tacaaaagtt
     8881 tatgttatct attctgattc tttgtctgca aattggctat tataaagctt ctcataaaat
     8941 ccaccctttt ccattaattc atcatgattc ccctgctcta taatacttcc attattcata
     9001 actaaaatca agtcagcatt gcgaattgta gaaagtctat gtgctataac aaaactagtt
     9061 ctaccattca taagatttct cattgctttt tgaagcataa gttccagcct agtatcaaca
     9121 gaactcgtag cttcatcaag tatcaatatt gaagggtctg atataaaagc tctagctatg
     9181 gttaaaagct gtttttcccc tagagatata ttagatgctt cttcatttaa aaacatattg
     9241 tatccatctg gaagagtggt tataaagtga tgaacatttg ctacttttgc tgcttgtata
     9301 atttcttctt tagtagctcc aaacctacca tattctatat tttcaaaaat ggttccatta
     9361 aataaccatg tatcttgaag caccatacca aacattgaac gcaaatcttt acgtttcata
     9421 tctcttatat ctactccatc aattttaata gcacctttct ttacatcata aaacctcatc
     9481 aataagttta ttaatgttgt tttacctgct ccagtaggtc caacaatagc taccatctga
     9541 ccacttttta cttctgcatt taaatcttct attaaagttg aattttctcc atatccaaaa
     9601 ttaacatgct caaatgtaac atttcctttt acattttcta tcttaactgg attttcaaca
     9661 tcaggtattt cctcttcttc gtctaaaatt tcaaatacac gttctatagc tgcaaaagaa
     9721 gattgtatta ctgtagataa ctgagtcatt tgtgaaagtg gctgatttat ctgccatata
     9781 taacgcacaa atgcttgtaa atttcctact gttattcctc cacttactgc atatatagaa
     9841 ccgacaactg ccacagctgc aattccaaag taagttacta atgaaaccat aggattcatc
     9901 atacttgata taaattgtgc cttaaatcca ttttcacaaa gttcttgatt tactttttta
     9961 aattctttta tagaatcttc ttctttacca tatagtttta tttcattaaa tccagtatac
    10021 atttcttgta cttttccatt taattttcca agagcatttt gttgcaatga aaatctactt
    10081 tgagattttt ttactacaaa tttagataca aaataactaa ttggaattat aaaaagagct
    10141 ataagagcca tatatatatt aattgtaaac atcattgaaa gtgccaaaat tatgactaag
    10201 attgagttta caatttgcat aaaactctgt tgcaatgcat ttgatattgt atctacatca
    10261 tttgatatac gacttaatac atctccaaaa ctattactat caaaataact aataggcaat
    10321 cttcttattt tattttcgac ttcatttctt aaatctctca ttgtgttttg aatagcattc
    10381 gtaagtagaa aacttgaagt atacgtaaaa attgcattgg caaaatatat acatgctaaa
    10441 atcaccaata tttttgttac ataatcaaaa tttacggaag cccctggtac tccttttgcg
    10501 atactaatta catctttagt caattgtgtt attatcaatc cttcagtttt aggtgcaagt
    10561 gcattcatag tagctgctga aattatacat ataatagcta taataaagga aaatttatat
    10621 ttctttacaa atggaagaag tctaccaatt gttttcttaa aacctttaga ctttttcatt
    10681 attctaattc ctcctttttt aactgagatg ttgcaatttc atagtatatt tcacagtttt
    10741 ttaataattc tttatgagtt cccattccta caacttgtcc ttcattgagt actataatct
    10801 tatcagcatc aataatagaa ctaattctct gggcaacaat caatacaatt gcatcttttg
    10861 tttccttctt caatttagca cgaagtattg catcagtttt aaagtcaagt gcagaaaaac
    10921 tgtcatcaaa aatgtatatt tcaggtcttc ttataatagc ccttgcaata gaaagtcttt
    10981 gtttttgacc tcctgataca tttgctccac cttcactaat caattcatca aactttctag
    11041 gtttttttga tataaactca tatgcttgtg caacttttgc ggaatattct aattctgact
    11101 ctcctgcctt atgtttccca aatctaatat tatttgctat gctaccagta aaaagcagtg
    11161 atttttgagg tatgaatcct atcttttttc ttaaagcttt taaatcatat tctcttatat
    11221 ctactccatt tatcttaatg ctaccttctg ttacatcata aaatctaggt atcaagttaa
    11281 ttagagtact tttcccacta ccagtacttc ctataaaagc gactgtttca cctgtttttg
    11341 cagtaaatga aatatcctta agtacagaag cttctccatc tggataggta aaagttacat
    11401 tatcaaattc tatgataccc ttattttcag tatccttaat tccattttca ggatttttta
    11461 tcaatggttc ttcatttaat agttctttta ttctatttgc agatacctct gctcttggat
    11521 acataataaa taccattgaa aaaagcataa ttgaaaacat ggcatggaaa agatattcca
    11581 aaaatgcaac caactgtcca acttgaagct ctccaatatt tatcttctca cttgaaatcc
    11641 aaaatacagc caaaacagct atatttaaca gtaaaaagaa tgctggttga gtaattgaca
    11701 taagcttaaa tagtttctta gaaacattag cataatatgt atttgttttt tcaaatcgct
    11761 ctgtttcata atcatcattt ccaaaagctc taattactct tattccagtt aaattttctc
    11821 tcgatataag gtttaattta tctagtcctt tttgttgttt tgaagatatt gcctgagata
    11881 cttttgctat tattgctact ccaataatta taaaaggtac tgatatagcc aatactatag
    11941 aaagttccac actggttcta attgtcatta ttatacttat aatgaacata actggagtta
    12001 ataaggcagt ccttagtagt atattaacaa attgttgaat ttgaaatgca tcattcgttg
    12061 ttcttgtaat cattgaagaa attccaaatt tattgtattc agtatgtgaa aattcttgtg
    12121 atttctcaaa tatgtcattt cttatatctc tggttacact tgttgatacc ttagcagaac
    12181 aataacccaa caatatacta cctacaaccc ctataataga aataataaca atcactattc
    12241 ccatttgttt tatgtaagct atattctgat ttgcaatacc attgtcaatt attttagcta
    12301 ttatagttgg aatccccaac tcgactaatg caaaactaaa tatagccagt atgtttaata
    12361 ctattaataa cttataattc tttaaataac ttaaaattaa tttcatattt ttctcctttc
    12421 ttaatttttg agatagtgta atcatgtaat aatactaaat ttataaatgc ttaattttat
    12481 aaaaaaagga gaaaagagtt aacgcactct cttctccagc atattctttt taatacaccc
    12541 tccgacaagt cgcttatatg ttaacatatt tgacaagtaa tgtcaattca tatagccaaa
    12601 agtcttttaa atgcttcgtt tcataacatt gtaacaaatt ggcatgtaat ttatttttgt
    12661 tttttactgt attccaattt tacaagttct ccaatattac tagctttctt aaaattcaaa
    12721 ttagtcttgt ctataccaga cttaaatagt gaaatccctc tccccaatat tattggcaat
    12781 atatatatat aataatcatc aattaagtta tctttcataa ataattttac tatatcgcct
    12841 ccaccaacta tccaaatatc ttttttatcc ttctcttttc caatttgctc aattaatttt
    12901 ttaggttcta aattaattta tagtgtgatt attctatgta aacatcactt ttttactcat
    12961 tcaataatac cctattaata aatcctcaaa ctaatttaaa taaactttgc ataaaattaa
    13021 aaatatatta tataaataat ttaaaactac actaacttat tgaaaattct aattattaca
    13081 aataaatatt gctctctgtt aacgctagtt ctataatata attataagct attaatatta
    13141 taaagccgat attactaata taataattat aatacttata gttaatttac ttttgttgaa
    13201 aggtggtaaa taacatgaaa atttcagaag tcgctactcc aaattttttg ctagatttag
    13261 accagttaga aaagaatata gataaaattc aacaaatttg tacaaataat aataaacaac
    13321 tttggcctat gcttaagaca cataaaagta cttacatagc gagacttcaa aaaaatgcag
    13381 gtgctagtgg ttttctagtt ggaacacttg atgaaggtga agctctgata aaagcaggtt
    13441 ttgaagatat tatgttggct tatccttaca tgggagaagt aaatataaat agaattgtga
    13501 ctatggcatc aaaaataaat ttaatctgtg ctacagataa tatagaatgt gctaaggctt
    13561 atagtgaagc tttttctaaa tcaaaaatag agtgcaagct acttattatt gtagattgtg
    13621 gcttacaccg ttttggggtt gaaccagaaa aagtggttga acttgctact gaaatttcta
    13681 agctagaaaa catcaagatt gttggtataa gttcgcatcc aggtcaagtg tatggttgta
    13741 gttctccaga aggtgttcca gatgtttgtg ttcaagaaga ttcttctatg gagaaagcat
    13801 acaaagctct aactgataat ggatttaata tagaaattgt cgcttctggt agtactccaa
    13861 cagttgaatc tgaagctgct tctaaaacta taactgctgt aagacctgga aactatgtat
    13921 actatgatgc tatacagata ggtttaggtt gtgctactga agatatgtgt gctcttactg
    13981 ttgtgtgcac tgtaatctca aaaaatagca gtggatacta tttaattgat tgtggaagta
    14041 agtgccttgg acttgataaa ggtgcacatg gaaatagtag tattgttggt tatggtaggg
    14101 tatgtggaca tccagaactt actattgatt cactttcaga agaagttgga aaaattaaag
    14161 taaatggtga aactgatata aaaattggtg atagaataag aattatacct aatcattctt
    14221 gttccactgc aaacttgaca agtaatttat taggttttag aggagataca atagaaaaag
    14281 tcatagaagt agatattcgt gaaaattcaa aacaaatcat cctttaaaaa cacatttatt
    14341 ctgatattaa catgaaagta tatttttctt aaaattattt ctaataacta atgttaatgt
    14401 tggataaata aaaaacataa attctagaaa tataaattta aaagaagagg ctgtctcaaa
    14461 atagagataa gcctctcttt cattgttgaa attatgaaaa tatacttgat ttcatacaaa
    14521 aagagtatct tatgaactaa aaagttcact ttgagatact ctcttttttt aattaatata
    14581 cacattaatt actatcttag tttattacta tatatcaatt actactcatt aatccttgta
    14641 tatattaatt cttatatatc atttatagtt aggttataat tttatgttat ttacattaat
    14701 cccataacag tgagtaaaac tcttactatt aacatcccca ctattgcatc aaatatagga
    14761 actgccaaca gtaacattct atacttagta ctggcatttg ctacaagcac tattctggca
    14821 taatgaccaa ctagagtacc cattaacata catggcataa ttaatatggt tgcttgtggt
    14881 gcagtgatta gaccttgtgc aaataagttt gcagctgtag ctgctcctgc tgccttagca
    14941 aagaatgctg ctatcaaaac tacaacagat tccccaggta gtccaaaaat acccattact
    15001 ggtccaaaaa tatttcctaa aatatcaact aaaccagtta attgtaaaaa ctgcactatt
    15061 acataaccca ttatcatggc tggtaatatc tgttcaacac ctatgtaaaa accttttttt
    15121 gctcccccca taaatatctc aacagcagtt ttcttaggtt tactatttac aattgcattt
    15181 ccagtatttt gttgactcat actacacagc ctccttagcc ttattctttt tatttcttac
    15241 acctatgatt aatctaacta gattagcacc aagtatttta cagaatatct ctataaggat
    15301 tattggacct aatgccaata atgctattgg taaaagtgga gcttgagtat ttattgtgtt
    15361 cagtataaca gctgaaccag catattgata tgctacaaat atagttcttt catcatctgt
    15421 tatttcccca ctttcaaata attctttcgt cattattgag gctacatctg aactagtaaa
    15481 tgaagataca aatgctattc ctgctattcc aggtatacca agcagaggtc taagcaatgg
    15541 attaaatatc tttgatgccg ctttcattcc tcccatagat tcaactacat ctataagacc
    15601 tacagcaaaa cagacagttg gaatcaaagt cagagcaaat aagaaaccat cttttgctcc
    15661 cgttcctcct ttacccataa agtctacacc atctgcaata gtaccaaatg aacctgtcag
    15721 attagcaaaa tctaatgctt taaggaagcc ttgactatct ttaaacactc ctgaaaataa
    15781 tactatcaat acaaataaag ataaataccc tttccatgtt accttattat ctccagctgt
    15841 tacatccata taaaatcccc ctttatacct caaatttatc taagtttaaa ataactgtag
    15901 aaattaattt caccctctca aacatagaat ctactactgc atattctctt gatgtgtggt
    15961 tccattcccc tcttacacca aatgaacaga ttgtaggaac gtttgcaata gttaaataac
    16021 ttgcatctga actacctcca agtctcttag catttaattc tccaaatcca ttttcttttg
    16081 acacttcatt tacaaatgta tgaaatctca taacatcttc tgtagtttca aatggcatca
    16141 tttcacttat aaaattaact tctgtagaag ttccttctat gtaagtttct ttacatatct
    16201 ctctaacttg ttctttaaca ttctccattt cttctacttt ttcaaatcta aggtctactt
    16261 ttatactaca atcttctgga atagaatttt ccactcttcc acccttaatc acacttacac
    16321 ttactgtagt tccaacatct aaattagtca atttttgtat gcgtagtatc ttattagcca
    16381 tttcttctat agcatttctt ccaccttcaa aatcattacc tgcgtgtgtt tctacacctt
    16441 ttacatgtat attacatccg attcttcctt ttctacctac acacaaacta ttatctacta
    16501 atccagtttc catattaaaa gcacaaagac caccttttgc ttccctcaat ataacatctg
    16561 cacctgttga atccttatgt cctatctctt catctccaga aaatactatt tttattggtc
    16621 tttctttgta tcctatttta tttaaagctt taataacata taaggaaatt attataccac
    16681 ccttcatatc taaaacacct gggccatatg cttttccttc tattatttta aatggattct
    16741 ctccaaatgt acctgtttca aagacagtat ccatgtggcc tgaaaaaatt ataggctttt
    16801 tatttatatt agaaccaagt gtacctatca atgtactacc attatctcca acatctacta
    16861 attcgcaatc taaaccttct ttttcaaact caaactttaa tctcttagcc aatttattta
    16921 cgctttcttt acaatgtgta tagctttcca tattaacaat ctctttccat aatgaaacta
    16981 tttcttctct attctcatca acaaacttag aaatttcatt taaatatgta ttcataatct
    17041 tctcctttat tttcaaataa aatgtatttc tttcctaaaa cctaagttta ttttaggaaa
    17101 tcttaaaaga ctagtcctta attacaaaat agcacaatta ttcttgacag tcaacatatt
    17161 ttcagtcttt tttatatttt ctgatttttc tttcaattat ccttttgtaa aataaattga
    17221 cgcgttttat ctactattat aaaatgaggt tataaattga ttgattagtt acaatactct
    17281 cgaaatttta aaggaggttt tatgaaatat aaaattggtt ttttgacaac atcttatttt
    17341 atgtcagata agtttaaaca agctcttaaa gaattaaatg atacttgtga aattacattt
    17401 attgagctca aaggggagaa tccttttaat aatttaccta atatatacta tgagcaagta
    17461 gataattttg atggatttgt atgcagtggt atagttccat atagtgaact tataataaat
    17521 ataaaagaca taaaagttcc attaaatttt ttaaagcttg atgaaagaga tttttataaa
    17581 tacttattca aattattaaa tagccaaaaa gatattgact ttacaaaatc atttatggat
    17641 tttttaagag aggacaacaa ttattatgat atatattcat taatagactc taataaatgt
    17701 ccatatacaa ttaaagattt taatatccct caacctgtat atgactttaa aaaattaaat
    17761 gataaattat tggaaataca tttagactta ttgcgagata ataagattaa cctttctttt
    17821 actagaaatt acatcattag ttgtgaactt aataagcttg gatatgattg tatttacatg
    17881 gttccatcta cagaatcaat cctgaataca tttaaatctc tggtgaatga aataacatta
    17941 caaaacttag acaaaaataa atctgcaact tgtatagtta cagtaaatag ttcagagtac
    18001 ataaatgaag atttgatatt taaaaatgat gagatacaaa atcaaatata taacactata
    18061 ttaaattctc tatcaagaca tggattctat ggagttcagg tcaaaaaaaa tgatatgaaa
    18121 atagagatac acactactaa agaaatgtta aacaatatga ccaataacta tacagatttt
    18181 tttatttcag aagatttaaa agaaattaaa tatagcttaa atataggttg gggcattgga
    18241 aatacaaata ttcatgcaga gcaaaatgct cgtcaagcta atggtaaatc tgcttctttg
    18301 aatggaaact gtacttttat agtaaatgat actaatgata caataggtcc tttatattca
    18361 aataaaaatt ctaataatat tgaagatagc tcaatagcca ataaagttgc ttcttttata
    18421 cctctatcta atacaaatgt atctaaaatc atgtgtatga ttaatgatag aaattcaaat
    18481 aatgtgtcag cagaaatatt agcagactat atgaacataa ctcttagaag tgctaataga
    18541 atattgagta tcttatataa agcaggaatt gcaactattg taaatacaaa actcgataat
    18601 caaagaggaa gaccaaaaaa aatatataaa gttgatttct tatcttttct aaataagatg
    18661 cagaaattaa attcttaata tttaattttt taataaaagc aatgtatttt ctctaatttt
    18721 aaagaatcaa aatgtttaaa ttttattaga atatacaact ttttacttta aaatacctaa
    18781 accttttatc agtgaaataa accataatat atcgtaactt attagaaaaa caaaataatt
    18841 tcatatacaa ataataaaat agccactaca atccataatt tgcagtggct actttttaca
    18901 ctatcactta ttacttattt ttaaaaatta attgtatttt ttaaataatt tatacacacc
    18961 tattatcagt aaagcaataa atacaagtat atctataaaa ataattattg taacatgtct
    19021 ggcaatattg taaataaaaa gtatagagaa tatttctata gacaacgcta caaaacacat
    19081 aaaattcgtt aaataatctg caatagtatc actataaaaa gcatgtattt gtaaccatct
    19141 ccatataaat ggacgtaaaa ggattctgaa tacaacacaa atgacagggt aggcataaat
    19201 aaatttttta tctacataat tagctacacc attattccat tggataggaa tttgaggtgg
    19261 caactttgga aatactgtta ttgcaatcaa caaacaagca atagtaataa ttccccaggt
    19321 aattttccct ccccatatat ataagaaact tacagagtca agtttaaaaa caggtttgtt
    19381 tttattccag tattctggca actcagttat gtattgttct actttcaaat tcaaataact
    19441 tagctcatca gattctaaca ttttattaca catagttttt gcattttcta agtctgatat
    19501 tttagtttcg agaactttct cctgtttctc tacaacttca actaaagata ccttctgtaa
    19561 tataatatta cggatatcat caatagtaat tcctaatgta cgtaaatatg caattttttt
    19621 gatgtcctct acattttcat ctgaatattc tctatagcca ttacgctcat tacgaagggg
    19681 tttaattaaa ttctcgttct cataaaaacg aatattagag cgtgtcaatc ctgttttttc
    19741 ttcaacttct ttaattgtca ttttaaacac tacctctcta ttctattaat ttataactat
    19801 aatatagtct taaatatttt cactctataa aattgtatat ttagtatatc ttaaaatcaa
    19861 actaattatc ttttataagt tttcatacaa taatatctcc tttcaataat atatcttttt
    19921 ttatatttaa aactatctta ttttctataa aataatgtat aaacaaggtt tacagtcaag
    19981 tatttttatt atttttttga tttcataaaa aaagcatagc aaattatttg ctatactttt
    20041 ttactaaatt atttattcta tatcttatat gaacttattg tttaactact acacaatact
    20101 agctttaatc atcatatttt ttgcaaacat actggcttca tatatttctt gttcatctgg
    20161 atgactttga gattcctcat ggttatttaa ttgttggcga atatgttcgt tgtcaggaga
    20221 aagttttaac atctctttat attttgcttt caatccttct gctatcttac cttgacatat
    20281 gaatgaacct aatatttcat tatcttttgg gataattgat tctatctttt ctattatact
    20341 agctccataa cttccttttt tacttgctcc cattgttcca aatagtgcta tctttttatt
    20401 gtgaatattt tcaagcactt gttttgaatt tttatcacaa attcccttgt ccacccaata
    20461 gcctaagaat actatatcat aattttcata gtcaatacca taatcaacta attcatttac
    20521 atctttaatg tctttttctt ctttaatttc atcatatata gtataagcaa tctttttagt
    20581 atttccagtt aaacttgaat ataaaactaa acttttcatg atgtctcctc ctctttatct
    20641 aaatacttat ctaaatcacc aaaaatatat taaccttaac aaattattta tttttataag
    20701 gatattctaa tctagtatac atccaaactg agagcgtgtt tgtaaagcat ctgcacactt
    20761 cttattacaa taacagcact ttttaatctc atctactctt ccatctttta ctttctgtaa
    20821 ccaattacta tctgctagta attgtcttga catagaaacc atatctactc tattatttga
    20881 aataatactt tctataaaat ctgggctaga caattttcca accccacata ctggaagatt
    20941 tgtgtgtttc tttacctcat cagctaaata taaaaaacag ccttcatctt taaagtaagg
    21001 atgattattg gttggtatag tatcttctaa ttttgaatga tttgcaagtg ttacatgaaa
    21061 actgtttaca cctagggatt caaatttttt aacaaaatac tcaacttccg aaaataaaac
    21121 tcctgcattt ccataatgag gattttcttg tcttattgca aatttatagt ctattggaat
    21181 gtccttaact tcatctcgga tactactaat tatttcgctt gcaaatctac ttctattatc
    21241 acacgttcca ccatattcat catttctatt attaaatata cttgatgaaa aacttcctac
    21301 aagcctatca ccatgaattt gaatcatgtc aaaacctgct ttttttgcat tcaatgctgt
    21361 tactttaaat aaatttataa tatttttaat ttcttctttg ggcatatttg ttatgtaatc
    21421 ttttactccg tcattcatta ttttttttat ctcatcatgt gaagtaattc ccatcttcat
    21481 aatatcttta attaaattaa catcataatc tgaacaaaat agttgtgctg atacctttgc
    21541 accagaattg tgtatttcat ctacaatttt cttgtatttc atgactccat cttcatccga
    21601 taggcttata gctaccttat gaaaactagg tctaatagat acatctccta gagtaatcag
    21661 agctactcct gacttagcaa tatcagaaaa ctttttaatt ttttcttcca atttaagacc
    21721 catgcttgta ggtgcaaaag atactctatt ttttaattcc aaatttccaa ttttaattgg
    21781 ttttaataaa ttacaataca tcctattctt cctccacagc tgtttttata tcctttacca
    21841 catgtaaatt ctttaccagt tctttatatt ctgtatccga gaactctttt tttatgtgat
    21901 tatcccactt tgaaaatatg ttttttatat cccctaatac ttcctcaccc ttatctgtta
    21961 ctctcaactg aaaagctcta ctatcattag ggttttggat tttttctatg tatccatctt
    22021 gttctaacct agatatagtt cttgttgtat gagctttatc aacttcaaat tctgtagaaa
    22081 catcattcaa agaacaattc ctatttttat taatataaat taaatagaaa tatagaccat
    22141 tcgtaagttt atatggtttt aaacattttt cacaataaag tttaaagttt ttttgcaagt
    22201 tacaaataat atatgacaaa ctttcatact gtaaattttt aaaatccatc ttaaatttcc
    22261 cttctataat tataatatgt ttgactatat caactatatt atattaaaca attaatatag
    22321 tcaagaatat tttattctct aaatctatgt tttattaatt ctttaaaaaa ctattatata
    22381 aaataatcat gataaaatta gaaattggaa tttttaatat gcactgtaca taaatatatt
    22441 ttatataaaa gtttatattt tcaaacaagt aatttttcga aaattgtcta aattcagtaa
    22501 aaatatggta atatatacat aagcaatata aatctataaa aaggagtgtt acatatgata
    22561 tctaataaaa tgcaaacttt agttgcaaat agttctgtta taagagctat gtttgaagaa
    22621 ggaaagaaac tttctgatat ttatggtgag gaaaatgttt ttgattttag tataggaaat
    22681 ccaagtgttg aacctccaga gactattaaa gcagttataa atgatatttt aaatgaagaa
    22741 tctccaaatt tagttcatgg atatatgaac aactcaggat atgaggatgt aagagatgct
    22801 attgctgaac acataaataa aaaagatgga ttaaatctta caagagaaaa tttaattatg
    22861 acttgtggtg ctgctggtgg tctaaatatt attttaaaaa ctcttttaaa tcctggtgat
    22921 gaagttattg cttttgcacc gtattttggt gagtataaaa attatacaga aaactatgat
    22981 ggaaaattaa tagaagttcc tacaaatata gagacttttg aaccagattt agatgctcta
    23041 aaaaatgcta ttactccaaa aacaagagct ttaataataa acactccaaa taatcctact
    23101 ggtgtcatat attctgaaga attattaaaa aatcttggag aattattgga ttcaaaacaa
    23161 aaagaattta atacaagcat atacctaatt tctgatgagc catatagaga aataatttat
    23221 gatggtgcta aagttccttg tgtactaaaa tactatagaa attcatttat aggatactct
    23281 tatagtaaat cattatctct acctggtgaa cgtataggat atattgttgc taatgggcaa
    23341 atggatgatt ttgatgatgt tatgtcttca ttaaatgttg caaatagaat acttggattt
    23401 gtaaatgctc cttctctttt tcaaagggtt attgcaagaa gtttagatgc agaagttgat
    23461 gtaaatattt ataaaaagaa ttttgacctt ctatataata gtttaatcga tatgggatat
    23521 tcttgtgtta aacctaatgg tacattctat ttgttcccaa aagctccaat tgaagatgat
    23581 aaaaaatttt gcaatgatgc aaaacaattt aatttattat tagtaccagg ttcttctttt
    23641 ggttgtccag gtcattttag agtatcatat tgtgtatctt atgataaagt taaaagttct
    23701 ttaccagcat ttgaaaaatt agccaaatta tataatttaa aataactaaa tcaaagtaat
    23761 tcaaataatt aactacctta gtatagaata cttacattct atattaaggt agtttataat
    23821 tttatgtact atattttata cataccatat tattccaata tgcttgaata ttcttatcta
    23881 tagtactaat ataaattaca aggaggtgtt tgacttgaaa aaaggttatg tttatataat
    23941 actgactacc ttatttttta gttcaatgga aattagtcta aaaactgtca ctaatgactt
    24001 taatccctta caaataactt tatcaagatt ttttgttggc ggtttagtct tactaccttt
    24061 tgctgtaaaa agattaagag ctcttagtct ttctattaca aaatcagact taaaatactt
    24121 tgcattttta ggttttatgt gtgtagtagt aagtatgtca ttgtatcaac ttgctgttct
    24181 aaacacaaag gcatctgtag ttgctgtttt gttcagttgt aatccagtct ttgtaatgct
    24241 tttagcttac ttaattttga aggaaaaaat atataggcac aatgtaattt cacttatatt
    24301 agaagttctt ggaattatag ttataataaa tccattgcat acaaaactaa ctcttagtgg
    24361 aatattctta acattatctt ctgctattat tttttcaatg tatactgtat ttggtaaaag
    24421 aaaaacctta aaatttggtg gaatagttgt aacctgcttt agctttatat ttggtagttt
    24481 ggaaatgttg atattggttt tactcactaa aattaatttt atcgcagata tattaaataa
    24541 aaataagctt catgtatttg caaatatccc tatttttagt ggatatacct tacacaatat
    24601 gcccattatg atttatgtat tcgtatttgt tacaggtgtt ggttatgcgc tttactttat
    24661 ggcaatggaa gctacatcta ctagtcttac atctttagta ttcttcttta aaccagtaat
    24721 atctccaata ctagcattat taatacttaa agaaattatc cctataaaca tggttatagg
    24781 aattttattg atagtaattg gttcaataat ttctattata cctacgataa ttactcaaat
    24841 gcataataaa cacgttgaag ccttgtataa ggagtagtaa ttgataatct atcatagtta
    24901 tacataagac aaaatttatt agatttaaac gcaatataaa agagatgcta ttataatagc
    24961 atctctttat ttatatttat tttaaattta ttaaaactct atttagctaa attttgcaaa
    25021 aagctataag tttgtggaca agctgatttt aacttactat ttgtatcttg atttaaatag
    25081 taatatgcaa atgattctgc aaaaaattct tctggatata cacctaagta gtttacatta
    25141 cctaaagaac gaccttcttt agcaaatatt tgtttgaatt gtgctgattt agatatatca
    25201 tttaatacta tatggtctat tgcatgtgct gtttcatgta attctaaatt tattgcatca
    25261 tgccctttac ctttgttact aaatcctatt ctaagagcta ctgtacttcc acctaaacct
    25321 ggaacatcat cccaagtttt tccagtacct tcccatccct taggaactac accttttaaa
    25381 taagcatatt ctttttcatc tgttaacttt ccacttaata attttatttt taagttattt
    25441 tgttttaatg catttaaata ctttccatct atattagcta atctatttac catagcatta
    25501 gcttcgtttt tatcgtaatt tccagttgga aaaactacta tttgactaag tgtgtcttta
    25561 ttttgttgta tagtagtact atctgcatgt gcacttactg gaactgaact tattaagaat
    25621 attgatatta tagctattaa taatttttta cttggtctca tattattccc tcctttgagt
    25681 taggccggga gtaataaatt tcaaaataaa aaagataccc aagagtatct ttgtatatac
    25741 aaaaagaaat ttttactctt ttcggcaact ggctggcatg gtttactaaa ctttagcccc
    25801 tatagctttg cgtgactagg tttccctagt tttgcctcat ttaattttat atctatatta
    25861 tagcttatat ctttttaatt gtctatatcc ctttggaact tttttctaaa aagttattat
    25921 ttttttacat aaatcttcaa aaaaaaatat cttctaacaa tattttcatt attaaagatt
    25981 gttttagaag atatttttta atataactta tatttttata atgttagggt ctaatttgta
    26041 tttttatttc ttcttaatac gataagtcct acaatagctc ctataaccaa aagtatttct
    26101 ccaataattg tagtactatc ccctgttttt ggtggtactg gtggatttac caaagtatca
    26161 tctttaactt tattattttt ttcttctgac actgatggat ttactacttc tggtattgga
    26221 ataatctgtt taacaggagt ttctatcatc tcttctgatg gtggtactgg cggattcaat
    26281 acctctggta ttggcggatt tattatatct tctgatggtg gtactggtgg atttataact
    26341 atagtatcct ctgtatcaga tgaacttgat ggtttccttg gtttatctgt gcttggtggt
    26401 actggtggat ttaccattgg ttcatctgta tctggaggta ttggtggatt tactggtgga
    26461 ttttcttgtt ttagattttc tatatttcca atatctacta tcttaccaat atcttcatta
    26521 ccaatttcaa ccttaacttt atccttcagt ttttcatatc cacgtggagc cattatctcc
    26581 actaaataat atgttcctgg tttttttaca ctagattgaa ttataccatc ttcatcacta
    26641 actaaatcct taactactat atttccaaat gcatcttcta aattgaactt agcacctgaa
    26701 agtacatttt tatctaaagc atccactttt ttagcttcaa aagtataacc ttgcttagta
    26761 gtctctactc ctggaggact tgaaccatta atctgagcca catttcgtat agtctcccca
    26821 acttttacat ttgtgaagtt tgcatcaaat gtaacccaac tttgcacagg ttccccttct
    26881 tttatctgtt taaattcgta tttatttact aatcttattg tattttttcc atctccagct
    26941 tcttttttaa gttcaagatt atcagaatat tttatattag atatttctag aactgagttt
    27001 acttcatcta aaagatttac ttgtcctgca tcataaactc cataagttga catattgatt
    27061 ttgtatttaa caatctggtt atcactactg tttaaaactt ttttatcaac ttcttttttt
    27121 gcgcttatta atccagaatt tttcttaaag tttatctcat catttttatc aattttacta
    27181 ttatttgcat caagaacagc tctatttata tagctatctt caatactaat tacctttaat
    27241 gtataagcta taaaaaactt tgattccact tcttctttac tgagattaat tgtaaatcca
    27301 gttataactt tatctacttg cccactttca tttctttttt cttctacttt atatgaaata
    27361 ttattggcaa ttttttcttt actccaagga gtccagctcc cattcattgg aatttctaca
    27421 actctaaaat catgcccagc ttctcctgaa gtagttaatc tcatgccttc tggtatatta
    27481 tctgttataa caacattact tattggtgat ttatcatcat ttattgaaat ctgatagttt
    27541 attacttgac caacttgagt aatatttgtt gctcctgaat gtcctttagt aagaagataa
    27601 tcatctcctc tatcaaatat acttacagta gcatcatctt cttgtatctt cttaccatca
    27661 gattcaatcc tagctacatt cttatattta ttaccatgtt ttgcattttt gtcactgatt
    27721 ctagccttat acttaacagt atacgattta tctatatttc caaaattaac tgaaatagaa
    27781 tttttactct gttcaatatt aaaatcacta acttcttttc catcacttgt tactacactt
    27841 acagaatcat ttatcaatgt caatccttca ggaagctcat catacaaaat aatatctttt
    27901 aactcttcct gcttttcatt tacttgtata ctgtaattta tatctttatt tttaactggc
    27961 ataaatacag tagttgattt ttttccttca acaagctttt taagtgttcc tttagcatct
    28021 ggaacatccg ttttatctcc aggttttatt tctacatcta tatctccact tccactttct
    28081 atttttccag tagtttcaat atgtattttt gcattagtat cttcatcaac ctttttaaca
    28141 tatgcttcca aacctatttt accttgcatt acactttggc cattaggtaa ttctctaaat
    28201 gtaagtgtat actctccatt actttctgtt ttatcaaagc attcacttgt ataatctaaa
    28261 ttaactttat tgaatacatc tggcacctta aaagttattg aatctcctgc ttgtattcct
    28321 tttgatgttg gagtataagt taaattaaat gatatttttt tcattgattc cgtttctatt
    28381 gtattgttat taatttttac aacaaatcca tagtcttcat tttcttcatt aagttcttct
    28441 tctaaaactt tcaataaatt ttcatcttct aatagattat cttcctctgg agttttttct
    28501 gtatttttat tgtctagtgg tttttcatct tctaaagctt gttctgactt tttattatct
    28561 gttgacttat cttcttctgg tatctgctct ggctttttat tatctattgg cttttctcct
    28621 tctggagttt gctctggctt tttattatct gttgacttat cttcttctgg ggtctgttct
    28681 ggttttttat tatctgttgg tttttcttcc tctggggtct gttctggttt tttattatct
    28741 gttgccttat ctttctctgg agtctgttct ggctttttat tgtcgctttc cttctcctct
    28801 ccagttgatg aattagttga accactttga atctgactat tctctcctaa ttctgaagca
    28861 taagatacag ttggatatat tgtagacacc accatactta aaatcataat taaactaatt
    28921 aataatgcct ttctatttcc tttcttcatg taaatctcac ccctttaggt tacctataat
    28981 ttataatcta atcttccatt aatatcgtat ataaagtaat ttttactaaa aaattataca
    29041 aaaaaagcta tgaaaataaa taaatttata ttcatagccg gttgcaccac tgactcagta
    29101 tatccataag gtgcccaata atagaatata cttcaacatc tctataatat ttcataaaaa
    29161 caattaaaat tgctttattt atattaaaaa tacaattata tacttctatt atattatgcc
    29221 tctatactat tgtctatcct ttttacattt tttaccttat gatgagatta attaataatt
    29281 aaataaaatc cttatctaca acaattacac aattatattc aggatttatc tccttaacta
    29341 attttgttat atcttctttt aagtcatctt ctgacatgtt tttggaaaat tcggaaggat
    29401 taactactat atcaaatatt aaattcttct tgcttccttt tccaactatt ctaaaatcat
    29461 gcatagattt tacaagacta tttttcttaa gtatttcttc aagttctttt ttggctgaca
    29521 taacttcttt atcttcaaga catattgggt ccatgtgaat tactagatat atatctaatt
    29581 tttcagatat ttctctctct gcagtatcta taatttcatg tatttccatt atatctatgt
    29641 tggatggaat ttctgcatgt atagatgcaa tacatctacc aactccatag ttatgaataa
    29701 ttaaatcatg tgtacctatt atatatttat aagataacaa tagctctata atagaattta
    29761 ccatttcttc atctggtgct tcccctaaaa gaggatttat agtatctttt acaagagaga
    29821 aaccagcata aagtatcact aatgatacta cgataccaac atatccatct atgggaaaat
    29881 tagtaaatct agctacaata aatgatataa ctacacaact tgaagtaaat acatctccta
    29941 aagcatcaag tgaaactgct tttaaggctg aagaatcaat tttatttccc ataaatttat
    30001 taaaacgact caaccagatt ttaatcatta tagatgcaat taaaagtata agtggtatta
    30061 cttcaaattt tacaggaatt ggatttacta tcctttctat agatgacttt acaaattgaa
    30121 gtccaaccaa catcaccata aatgctacta ttaatgctga taaatactct attcttccat
    30181 gaccaaaagg gtgttcttta tcagctggct tacttgctaa tttaaaacct atcatagtta
    30241 ttgctgaaga tgccatatca gaaagattat taaatgcatc agccattata gctatactag
    30301 atgtgagcat tcctatgaat acctttatca caaataaaag taaattggat aatatgccta
    30361 ctacaccagc tacataacca tacttatttc taacatctgt attttgaacg ttttcgctat
    30421 ctctgataaa tgttttgact aggattttgg aaaacatgaa acttacctcc ctgcccttta
    30481 ttttattaac aaattttata atctatatct ttatttatga taacataatt tatatataaa
    30541 attcttaaaa atcactctac ttcagtaaaa tattattcta tatatctatt tagatacgaa
    30601 ttttatattt agtaaagttt ttatggctta gtgtctgttt aatagattct atataagttt
    30661 ttacaaagat tatttattat gataatatca tttttcccaa gtattactta gaatatgatt
    30721 tttttgtttt gtctgtacat attttaaatt tatactatat ttatctatat tttataacct
    30781 tatgatacac tataactata agtttttaaa tggaaaggaa tgaaataaat catgtttttt
    30841 atcagttata tttacacaaa atcacctatt aaatttgata ctcctttgca aaaagaggca
    30901 tataaaatat tacaaaaatt agatattgac tttgaatgtg ttgacacaga tgaagcaatt
    30961 acaatggaag attgtgttca gattaataaa aaattaaata tgaaaatggt aatataaaac
    31021 aacattaaac aaacaaaaac cgcaaagtta caatatatag tactttacgg tttcataaga
    31081 attaattttt actattaaag ttcatagttc tactattttt cattgttcta agaattagct
    31141 ttacaaattc atttgacaat aggatagtgg atgcaaatag tattatcttt atccacatat
    31201 caaagtccaa agaaacagaa ttaaagaaac tctggaacac ttgtgtaaat attatttgaa
    31261 ttatccctgt aactactatt atttgcaatg ccagtttatt tttaaagaaa tttggtattg
    31321 tactatttaa accaaactct ctacaattta atgcattaaa aagggcactg aatgcaaata
    31381 aagaaaatat aacagtacct tgttcttctg atgtagctcc caatatatta aaagctgatt
    31441 gagtaaatac aattgtaatt ataagaatag catttataat aatatttaca aacatagacc
    31501 tagctattat tccagaatgt ctatttattg gttttctttt caatacataa tctctaacag
    31561 gttctaatcc taatgctagg gctggaggac catccattat tatatttacc cataataatt
    31621 gtattgtagt aaatggcata tccttaccag taagttgaga tattatagca attataaatg
    31681 ctactatatt tacagtaagc tgaaactgta taaatctttg aaagttctca tatatacctc
    31741 ttccccattt tattccctct actatagtac taaagctatc atcagtcaat attatatctg
    31801 ctgcattttt agatacttct gttcctgaaa tacccattgc aattccaaca tctgcttgac
    31861 taagtgctgg ggcatcattt ataccatcac ctgttacagc tacaacttcg ccactttttt
    31921 gaagcgctga aactattctc atttttgtat ctggtttact tcttgcaaca atagatattc
    31981 ctttgatttc ttctctcaat tctttatctg tcaatacatc tatatatgtt gcttcaactg
    32041 cctttttccc atcatttaat agtcctaatt catttccaat agctgttgct gtatttatat
    32101 tatctcctgt aagcattttt acatctactc ctgcattaaa tgctttatca atggaatctt
    32161 tgaccccttc tctcaatggg tccactattc ctacaaatcc actaaaaact aaattatctt
    32221 ccttcatata acttcttgaa tttcctatta aattcaattc accttctgaa gtcattgcaa
    32281 cttctgtttt agaattactc atttttttat aagcaaatcc taatgttctc atagatttaa
    32341 tttgtaactt cttaatctca tctaaaatac ttttttctac ttttggagtt attggaacaa
    32401 tattttttcc ttgttgtaca taagaacatt tttttaataa tacttctgga gcaccttttg
    32461 aaagtaatat atctgaatcc tcttgacgaa ttaatgttga catcttcttt tcttctgaac
    32521 taaatggtat ttgtgatatc aaatacgttt gttttctcat ttcattatag ttcttatcat
    32581 tatgatataa aagtaatgca cactctgttg cgcttcctat atatttaaat gaattatctt
    32641 ctttttctat atctgcagtt gaatttacta tacagttttg ttcaaaatag ctattacttt
    32701 gatactctcc tccacttata tatttaccat caacatatgc tacctctacc atcattttgt
    32761 tttgtgttaa agtccctgtt ttgtcggaac atattacaga aacagaacct atagtttcac
    32821 aggcttcttt ctttgttact aatgcattta tctttgccat cttttgcatt gttatagcta
    32881 aggtaatatt tatcatagtt ggcaaacctt ctggaacagt tgcaactatt aatgcaatac
    32941 aaaccatata tgcattttta gcaggttcta atgattgtaa gaaagataat acactgcttg
    33001 tatctaaaat taacatacct tttctctgca tctgtataat cataaacata cacaataaag
    33061 tagctattat gcctgatatt cctgctattt tagcacccaa cttccctaat ttaatttgaa
    33121 gtggagtttg ctggtcttca tttgataaat tctgtgctat cttacccatc tctgtcttat
    33181 caccagtatg agtgacaacc attatgcccc taccatatgc tacaagagtc cctccaaata
    33241 ccatattgac ttgctttgca ggtattgcat cctgttcgat tatttctgtt ttagaataaa
    33301 ctacttccat atctaataca gcatcagcat tcttagctac atcatcagat tctcctgtta
    33361 gcatatcttc tctaagtttc aaatttatag actgtataag tcttccatct gctggtatca
    33421 tatccccagt ttctatatat acaatatctc ctggtactaa atcatttttt gatattttaa
    33481 ttatcttccc atttctaagc acctttactt ctatattttc tgttaatttt gacagggcat
    33541 gagctgcttt tttagatttt ccttcagtta ttatgcctat agaaattcca ataaaaatag
    33601 cccctaaaat acctaatgcg tcatgtaatt ctcccacaaa agaacttatt actgctgctc
    33661 ctatgagaat taatatcata ggttctgtca aactttctcc caactcgtcc caaaatgttc
    33721 taccttcttt tatagtaaat tcatttaatc catatctaag cttcctttct tctacctcat
    33781 tatcatcaag tccaatttct ggatttgttt ttaagtattt taatacttct ttggtaggtt
    33841 tattataata cctcataact ttatccccct tgttaattat ctataaggaa ttatatgctt
    33901 atgatagctt gtatattact tttcaaaaaa aataaggtgt tgattaatca acaccttata
    33961 gtggttatat attattaaat tttatgttac aggctttata aattgtgagc tatacaaatc
    34021 aaaatattta atcttcaaaa tacccttctg gatataatgg aaacttagat ataagttctt
    34081 gtgcctctgc tttacattca tctaatactt ctttattatc aatattttct gctaccttat
    34141 tcattatccc tgctatctgt ataacttctt tttctttcag acctctttga gatattgatg
    34201 taagacctat acgaacacca ctagttacaa atggtgattg tgggtcgtca ggtataacat
    34261 ttttattaac tgttattcct acatattcaa gagctttttc aaattgtttt cctgtaagat
    34321 tcttacttct taagtcaacc attactatat gattatcagt acctccactt acaatactaa
    34381 aaccatgtga aatcagttca gaagctagag tctgagcatt tactacaact tgctccatta
    34441 tctttttaaa tttatctgta cttaaatata atagtgaaaa ggcttttgct gcaactgtat
    34501 taagatgtat agaccctaat gttcctggaa aaacaccttt atcgagtttc tttgcatgtt
    34561 ctgctttaca aagtacaata ccacttcttg gtccacagaa agtctttgtc gtagatgaag
    34621 aaacaaaatc tgcataaggt acaggactag gtattacttt cgctgcgact aatcctgcaa
    34681 catgtgccat atctaccata aagtaagctc ctacttcttt tgcaaccttt gatattcttt
    34741 cataatctat taatcttgga tatgaacttg cccctgcaat tataagtttt ggtctacatt
    34801 cttttgcctt tgcttcaaga gcatcataat ctatacgtcc agtatttggg tctaccccat
    34861 aaaattcata tttataaatg tcatgtaaaa aattaactgc gctaccatgt gtcaagtgtc
    34921 caccttggtc aagacgcata cttaaaacag tgtcatttgg ttttaatatt gatgaatata
    34981 cacaatagtt agctgtagaa cctgaatacg gttgtacgtt tacatgttct gctccaaata
    35041 cttcttttgc acgttttatt gctagggttt caagtttatc tgcttcttca gaacctgctt
    35101 gaaaacgagc ccctggatag ccttcttctg ttttatttgt aaatacacat ccacttaatt
    35161 caagtacttc tgttggtgct gtactttcag aagctatcat ctcaatattg tgttcttgtc
    35221 taaccaactc atcagctaca atcttgtata actctgggtc tgaaattttt gttgttttta
    35281 acataataat cctcctctta attaaagaat atattttatt agtttaatct tcattgataa
    35341 atttattata acggtctata aaacgtaaga tattcctcca ccaggtccta atggtatgcc
    35401 aatacccatg aatagtaaca atattattat ttctattaat gtaaatacca ctgagtatgg
    35461 aatcatattc gatatgacag tacctatacc tatatcttta tcatatcttc tggcaaaggc
    35521 caatataact ggaaaatacg gaaaaagtgg acttattgga tttgttgaag catctccaat
    35581 acgataagct atttgagtta atgctggatt aaagtctagt agcataaaca tgggaacaaa
    35641 tataggtgct aaaatcgccc attttgcaga agcacttcct acaaataaat tgataaatcc
    35701 agatagcaat ataaatccta ttatcaatcc atagctaggt atccccgact ctgctagtaa
    35761 ttttgctcct gttattgata aaattgttcc taagttacta agattaaata aattaataaa
    35821 ctgggatgct ataaatgcta ggactatata tccacccata tcactcatac tactacccat
    35881 catagatact aaatctttgt cactttttat cttcttactt acttttccat acactaatcc
    35941 tggagttaaa aatataatag tgattatagg aactatacct ttcattaaag gtgcattact
    36001 agatagtata gaaccagtct ctggatcttt cataaatgca ttgtcaccta tacataaggc
    36061 aactatcact actactacaa ctaacaatga taataaagcg tattttatac ccttattttc
    36121 aagttcactc aattcctgta tatccttatc atttgttgaa tcattatatt ttgtaaaacg
    36181 aggagctata aatttttcag ttacaaatgc tcctgcaaaa gttaaaacta tcgctgatat
    36241 aaaagcaaaa taaagattca ttgctggatt gccttggtaa gatgggtcca tcatttgagc
    36301 tgctggtatt gtaaatccag ctaacaatac atctgtagta ctaagcataa catttgctgc
    36361 aaatccccct gcaacacctg caaaagctgc aaacatacct acaagaggat gtcttccaat
    36421 tcctaaaaac acaagtgctg caagtggtgg taatattata aatcctacat ctgctgctgt
    36481 atgtgataac atacctgcaa atacgattgc tacagttaca agtttttgtg gaactttact
    36541 tatacccttt ttcattaaca cttccataaa tccagatttc tctgcaacac ctgctccaag
    36601 cattgtaacc agtactaatc ctaaaggagc aaatgactga aagtttgtaa ctatgctacc
    36661 taaatatgat tgaatctgct ctttctctag tagatttact acctttacaa cttcttttgt
    36721 agaaggatgt atttcttcta ctcctaaatt agatataact gctgacaata ttacaacaat
    36781 tatacatagt aataaaaata tggttactgg gtctggaagt ttatttcctg ctctctctac
    36841 aacatttagt gccctcatca ataatccact atctttgttt ttttcctgtg aattaatttt
    36901 cctcaaacta ataccccctc ataaacttta tctccagaat gctctatctt aaattttatt
    36961 ttttaattta tccatataat ttataacaga ctgacatagt acatttgtac ctactaatat
    37021 agaattttta tcagctttaa atttaggatt atgccactga tatatacaat cttgttcttt
    37081 gttgcctacc cctaaccagt aaaaaaatcc tggggctttt tccatgaata tagaaaaatc
    37141 ttctcctcct gtagaaggta ttggatcaac tatagcatct tctgaataca aatcacacac
    37201 agacttacaa gctattgcgt acatctcttt actatttata acagctggta aatcaaataa
    37261 ataatctagc tttgcagttg cttgatatcc acgagctatc tcacaaacta tattttctaa
    37321 attttctgat attttctttc gtacttcatt actaaagctt ctacatgtgc ctgtcatatc
    37381 taccttttct gaaattacat tatttgcagt ccctccattt atagtaccta ttgatataac
    37441 agctgattct aatggactta tgtttctgct tactatggtt tgaataccca ttataattgc
    37501 acttgatgct actatagggt ctattgttct gtttggtata cctccgtgac ctccaaatcc
    37561 atttacttct atcttaatag tgtctactgc tgccattaac ccacctaact taacacctat
    37621 ttttccacaa ggtatatctg gatgattatg aagtccaaat atagcatcaa cttttggatt
    37681 ttccattact cctcgttcca ctagcatctt cgcaccttta ttgacttctt cggctggttg
    37741 aaatataaac tttacatttc catgaagact atctctaata tgagacaata catatgcaca
    37801 tcctacaagg caagacatgt gtatatcatg cccacatgca tgcattatac catcatatct
    37861 ggatttatac ttaatatcaa cctcttcata tattggcaat gcatcaatat ctcctcttag
    37921 tgctactgtg ggaccatcat acttcccttt taataatcca acaactcctg tttccattcc
    37981 taaatctaat atttctatgt ctaaacttac taataaatct tttatagctt ttgtagtcct
    38041 aaattcttta aaacttaatt cggggtgcat atgaatatct gtaaaaaaat ctaaaatatc
    38101 ttctttatac ttttctgaga ttaaaataag ttcatgcata ctaacacctc tccaaaattt
    38161 tattttttta ttttttataa tttaactaca aattatataa gttaataatc tttataaaga
    38221 tattttttat aaatttaatt t
//
LOCUS       DAEQAF010000031        37952 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.032, whole genome shotgun sequence.
ACCESSION   DAEQAF010000031 DAEQAF010000000
VERSION     DAEQAF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37952
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.032"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            30..368
                     /locus_tag="KRN00_001651"
     CDS             30..368
                     /locus_tag="KRN00_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBH1827518.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGRP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(495..1784)
                     /locus_tag="KRN00_001652"
     CDS             complement(495..1784)
                     /locus_tag="KRN00_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1827519.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            1864..2568
                     /locus_tag="KRN00_001653"
     CDS             1864..2568
                     /locus_tag="KRN00_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBH1827520.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKPNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            2660..3706
                     /gene="selD"
                     /locus_tag="KRN00_001654"
     CDS             2660..3706
                     /gene="selD"
                     /locus_tag="KRN00_001654"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2708..2710,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBH1827521.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            3724..5136
                     /locus_tag="KRN00_001655"
     CDS             3724..5136
                     /locus_tag="KRN00_001655"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBH1827522.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVAELRKAFN"
     gene            5193..7076
                     /gene="selB"
                     /locus_tag="KRN00_001656"
     CDS             5193..7076
                     /gene="selB"
                     /locus_tag="KRN00_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBH1827523.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            7181..9919
                     /locus_tag="KRN00_001657"
     CDS             7181..9919
                     /locus_tag="KRN00_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBH1827524.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     ISQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLVSLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDIYY"
     gene            complement(10038..10982)
                     /gene="manA"
                     /locus_tag="KRN00_001658"
     CDS             complement(10038..10982)
                     /gene="manA"
                     /locus_tag="KRN00_001658"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBH1827525.1"
                     /translation="MEPLFLKPIFMDRIWGGTALKDKFNYEIDSPTTGECWAISSHKN
                     GDCLIENGKYKGKKLSELWNKNRELFGNTPGDKFPLLTKILDANDNLSVQVHPNDEYA
                     KKNENGELGKTECWYVIDCSDDAEIIIGHNAKSHKEFVNMVNNNEWDKLLRKVNIKKG
                     DFFYVPSGTIHAICKGTLILETQQNSDTTYRVYDYDRTDNSGNKRELHVQKSIDVTNV
                     PHINFDTDYKIVSTSDFKCTTFVSNEFFSVYKLDVFGKCNFTHNTPFSLYSVLDGNGK
                     LIHNSVEYNLKKGMHFILPNDFGDFIFEGNLEIICSHI"
     gene            11155..12516
                     /locus_tag="KRN00_001659"
     CDS             11155..12516
                     /locus_tag="KRN00_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1827526.1"
                     /translation="MELFKAESKKYEKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TLEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            12604..14493
                     /locus_tag="KRN00_001660"
     CDS             12604..14493
                     /locus_tag="KRN00_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1827527.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAIKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISSVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            14508..14963
                     /locus_tag="KRN00_001661"
     CDS             14508..14963
                     /locus_tag="KRN00_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1827528.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEGESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            15022..15339
                     /locus_tag="KRN00_001662"
     CDS             15022..15339
                     /locus_tag="KRN00_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1827529.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            15364..16626
                     /locus_tag="KRN00_001663"
     CDS             15364..16626
                     /locus_tag="KRN00_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1827530.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            16731..17795
                     /locus_tag="KRN00_001664"
     CDS             16731..17795
                     /locus_tag="KRN00_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1827531.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARDIIGSYG
                     YSGNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            17849..19027
                     /locus_tag="KRN00_001665"
     CDS             17849..19027
                     /locus_tag="KRN00_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH1827532.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFVPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGTFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(19218..20276)
                     /locus_tag="KRN00_001666"
     CDS             complement(19218..20276)
                     /locus_tag="KRN00_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBH1827533.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKNGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMNLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            20343..20714
                     /locus_tag="KRN00_001667"
     CDS             20343..20714
                     /locus_tag="KRN00_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBH1827534.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            20751..21425
                     /locus_tag="KRN00_001668"
     CDS             20751..21425
                     /locus_tag="KRN00_001668"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBH1827535.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            21674..22513
                     /locus_tag="KRN00_001669"
     CDS             21674..22513
                     /locus_tag="KRN00_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBH1827536.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            22757..22853
                     /locus_tag="KRN00_001670"
     tRNA            22757..22853
                     /locus_tag="KRN00_001670"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22791..22793,aa:Sec,seq:tca)
     gene            23003..23710
                     /locus_tag="KRN00_001671"
     CDS             23003..23710
                     /locus_tag="KRN00_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBH1827537.1"
                     /translation="MENNFTTRTSFLVGDDGIEKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(23852..24688)
                     /locus_tag="KRN00_001672"
     CDS             complement(23852..24688)
                     /locus_tag="KRN00_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1827538.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            24876..25781
                     /locus_tag="KRN00_001673"
     CDS             24876..25781
                     /locus_tag="KRN00_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBH1827539.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVDFVLEYFSKNNKKIYLRGITTEVVE
                     FLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKKNQKKRNHINYFLKEYAGRYEAKL
                     LDKENFDECLVLMKEWESNKEENNEFDESMDDELIGIKKIFNHYDILKDKVKVFGVYV
                     DGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPFINQQFLVSEFKDVEFVNREEDLG
                     IEGLRKAKLSYHPCRFVEKYSVREA"
     gene            25790..26974
                     /locus_tag="KRN00_001674"
     CDS             25790..26974
                     /locus_tag="KRN00_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1827540.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNISYVVGVSTLPEGRGAGYMNKVMKFTLNELYR
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIEKDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETLNCIFSKKNNYINE
                     YI"
     gene            27089..28390
                     /locus_tag="KRN00_001675"
     CDS             27089..28390
                     /locus_tag="KRN00_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBH1827541.1"
                     /translation="MGVIIIQIRRPLLIILMFVVAISFIITNNTKNDEELNDKIITIQ
                     GVVKGKIEKKRYNQYKVGVFLINDYTKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGR
                     YIKSTGYKGIVYINNYKIIDKNKLYSLIGEIKFYISKTYRYLYKKNSDFINSILLAEV
                     ENLTEEQKEIFTRTGTSHVISISGLHTGILCVIISFLLRGINKLYKLLILSIFITLYC
                     IMVGASPSIIRSIAFVMIFYLSIFIDRKKDGISALSLIGIILIMNNPYVIYNVSFQLS
                     FLATLSILIFYNKINSIIKLSMVSLTISSNILTLPIIYYTFKGIPLLSIIGNLIIVPF
                     VGVIMYLSIASLIVFKVSVVIAKIISFFNSTFIESIFFLLEKISNLSFAYINIENPKF
                     YIVVIYYIGVFFYIFYIEGKEIKEQENELQGYYKECKREKL"
     gene            28344..29387
                     /gene="holA"
                     /locus_tag="KRN00_001676"
     CDS             28344..29387
                     /gene="holA"
                     /locus_tag="KRN00_001676"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBH1827542.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(29574..29840)
                     /gene="rpsT"
                     /locus_tag="KRN00_001677"
     CDS             complement(29574..29840)
                     /gene="rpsT"
                     /locus_tag="KRN00_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBH1827543.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            30439..30960
                     /locus_tag="KRN00_001678"
     CDS             30439..30960
                     /locus_tag="KRN00_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1827544.1"
                     /translation="MDIAKLILNPARLRILQYIRLHGSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            30994..31770
                     /locus_tag="KRN00_001679"
     CDS             30994..31770
                     /locus_tag="KRN00_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1827545.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEALSNNYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKL
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            32113..33066
                     /locus_tag="KRN00_001680"
     CDS             32113..33066
                     /locus_tag="KRN00_001680"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBH1827546.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKDELVDIFGQDENKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            33084..34103
                     /locus_tag="KRN00_001681"
     CDS             33084..34103
                     /locus_tag="KRN00_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBH1827547.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            34134..34385
                     /locus_tag="KRN00_001682"
     CDS             34134..34385
                     /locus_tag="KRN00_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827548.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            34667..36472
                     /gene="lepA"
                     /locus_tag="KRN00_001683"
     CDS             34667..36472
                     /gene="lepA"
                     /locus_tag="KRN00_001683"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBH1827549.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            36621..>37952
                     /locus_tag="KRN00_001684"
     CDS             36621..>37952
                     /locus_tag="KRN00_001684"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBH1827550.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIRCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEVIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVGLFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYT"
BASE COUNT        15125 a         3999 c         6438 g        12390 t
ORIGIN      
        1 tcaatatcaa ataaatggga ggaaatctaa tgaacttatt agtgattggt ggtcatgaaa
       61 gaatggaaaa agattatatg gttatggcca agaaaaaagg ttataagaca aaggtatata
      121 ctaccatgtc atctaaatta aataattcta taggaagacc agatgcagtt gtcatactta
      181 catcaactgt ttcacataag atgtctagaa cggttgagtc tcaagctaaa aaacaagata
      241 tattaatcgt aaggcataaa aatagtagta aggtagcatt taatgaatgt ctagatatgg
      301 ttgatgaatg tctgggaaat tgttcaaaat gtaagcttaa agacaaacaa aaacaaaaaa
      361 atatataggt ataaaaaata cataaacata aaattaaaag tactgagata atagttataa
      421 ttattatctc agtactttta gatttataag gataagtata gtataaattt tttattataa
      481 tttccaacta cttgttactt tttcatattt tttttacttc tagctttttt tctttttttc
      541 ttctttatat ttgaagctat tataaataaa actaaaagca ctagaatacc tgcaataatc
      601 ttaacaaaag tcattaaaac attattttca gtcaaaaatg gaagactgct atcaagatta
      661 ttttttgcaa ttaagtctat actgttttct agtttaccat tattatatac atttaaagta
      721 ccaaccttag cccctttttt tataggcaaa tcaattttat ttaactctgt tttggtatca
      781 taattgcctt gagattcatc tttttctaag aatatcctat aactattttt tggttcataa
      841 atcaattcat gttgttttgt aaacaatact tttttagtat ctgtgtattt ttctttatca
      901 acaatagtag cacacttaaa gttatcaaat ccataatcaa tcagaatacg tgagtctaaa
      961 tataaatcag cattagttga attaaataca gcaacgataa ctcttctgcc atcttttaca
     1021 gcactcgata aaagacattt accagcagca tcagtatatc cagtttttat accatcaact
     1081 atatcatatt ttatatttat aggttgacct ttgtatgtaa tcttatcatg tgatgtcaaa
     1141 aacttattag tgtttacaaa gtatctctca taaggatatg cttttgtagc ttcaaattta
     1201 agtgacttag tttttacaat ttgtctaaaa gtatcattat tcatagcttc tctagctatg
     1261 agagccatat catgagctgt tgtgtagtga tttgggtctg gtaatccatg aggattatta
     1321 aaatgagtat tagtagctcc aatttttttt gcctcagagt tcatgaggtc aataaatttt
     1381 tgtacattgc caccaccaac atatctagct aatacaaaag cagcatcatt agcagaatga
     1441 accaaaagag catctagtaa ctgctttaca gtaaaagatt ccccattttt tagatacata
     1501 ctagagccat ctatttgagg taaatcttta atttctatta cttgatttaa atctttaacc
     1561 tcctttagaa ctaaacaagc tgtccatact ttagttgttg aagctggata aagcttagaa
     1621 tttccatcct tattatatag tattttgcca gactcatagt ccattaaaac tgcatgttta
     1681 gcaactatag ctggttcatt atctgcaaaa gagatattag agcttcctaa aaatgaagta
     1741 aatatcaata aacagattaa taaaagtgat aaatttcttt tcattgtgag cctccaaatt
     1801 ttaaattcat cttttagtat agcatatatt tgtcaataat taaaagaaag gagtgattaa
     1861 tatatgaaaa aaaaggtaaa atttatttcg ttttttgttt tatttatttt aataatatca
     1921 tcaataatcg tttataaatc gcttattttc aaagatgata tttatgttgt aagtaaaaaa
     1981 aatttaccta atgaaaaaac acatgttgta gagaatgaaa ttaaaggtga agataataat
     2041 cacagtaaag taactaaaga catagataaa aattttcaaa ataataaaat aactatatac
     2101 ataagtggag cagtaaatag acctggaatt gtaactatag agtcagacaa gagactttat
     2161 gatgctgtag aattactagg aggaacgaca aaagaagcag atttaaatgg agtcaatcta
     2221 tcagtaagat tagaagatga acaacattac ataataccta aaataggtga agcaacatct
     2281 gttacaagta atgatgattc caataaacca aatcagaaga atgagtcaag aggtgagcct
     2341 aaaaataaat ccaataaaaa tatatctaac gaatcaaaag taaatataaa tgtagcgact
     2401 atagaagagt tggattctct acctggggtt ggagaagcta cagccaataa aattttacaa
     2461 cacagagaag aaaatggaca gtttagttca attgaggaaa taaaaaatgt aaatggtatt
     2521 ggagataaaa agtatgaaaa tataaaagat ttaatttgtg tagactaaaa tataatacaa
     2581 aacttacata tagatatgtt attataaata tgtatgtata tgtgtgtaca tgtggaaatt
     2641 tagtaaagga ggcactttta tgaaaaaaga acaaaaaaaa cttacagaga tgacaacagc
     2701 aggtggttga gccgctaaaa tagggccaga ggttctggca tcagttttat ctcaattgcc
     2761 taaaaatgat aatatagaaa atttattagt aggactagat acagcagatg atgctgcagt
     2821 ttataaatta aatgatgata tggcacttat ccaaacttta gacttcttta caccaatggt
     2881 agatgaccca tacgtatttg gtcaaattgc tgcatcaaat tcactatcag atgtatatgc
     2941 tatgggaggc aaacctttgg ttgctatgaa tattgtttgt tttccatcat gccatgatat
     3001 ggatgtactt gcagaaatat taaaaggtgg gtttgataaa gtgaaagaaa gtggagcact
     3061 tttggttgga gggcatactg tagatgacaa agagcctaaa tatggtcttt cagtttctgg
     3121 gattgtaagt ccaaataaag ttttatcaaa tgctactgca aaacctggtg ataagttaat
     3181 tataacaaaa ccaattggag tgggtgtatt aaatacagcc atgaaagaag gtatggtaga
     3241 acaacatata gcagataaag taatagaaat aatgatacat ttaaataaat atgcagcaat
     3301 gagttttgag aaatttgatg taaattcggt tacagatata actggttttg gtctacttgg
     3361 tcatacttta gaaatggcca aagcttctga agtaagtatt gaaattgaat caaaacatgt
     3421 accaattatt gaaggtgcaa tagaaatggc acaaatggga attatacctg ctggtatgta
     3481 taaaaatatg cattatgtat ctaaagatgt agaagttgta ggaaatatag aagttgcagt
     3541 tcaagatatt ttatacgacc cacaaacatc aggagggttg ttaatttcag taaaagaaga
     3601 acttgcagag gagcttgtaa aagatatgaa attaaatgga gcaatagaag ctaaaattat
     3661 aggttctgta gttccaaaag gggaaaaata tattacagtt ttataaaata ttatagagaa
     3721 agagtgattg ttttgagcaa aagagaattg tttgcaatgt tgccttcagt tgatgaagta
     3781 ttaagtgata atagaattgt agaaataata aatgaatatc ctagaagttt agttttagaa
     3841 tctgtgagag aagtaataga tttaaaaaga caatttatat taagattaaa agaagatgca
     3901 tcaaactctg taacaataga gtttggtgaa ataatagaat ctgcaataga gagagttaag
     3961 ttaaattact cattatcttt aaaaaaagtt ataaatgcaa ctggtacagt tattcataca
     4021 aatttaggaa ggtctttact tagtgaagat ataaaagatg aattatggtg tgctgcttca
     4081 aggtattcaa acttagaata cgatttggat aatggagaaa gaggttcaag atactctcat
     4141 ttaactagta caataaaaag acttactgga gcagaagatg tactagttgt aaataataat
     4201 gcagcggcag tacttcttgt acttagcaca atggctaaag gaggagaagc aattgtatct
     4261 cgtggagaat tagttgaagt aggtggttca tttaggattc caagtataat ggctcttagt
     4321 ggtgcagaat tagttgaagt tggttcaact aataaaactc atttgaaaga ttacaaggag
     4381 gccattacag aagatacaaa tgtattgatg aaggttcata caagtaatta tagaataatg
     4441 ggattcacag agagtgtttc tatagaagaa ttggttaatt taggtaaaaa atataaacta
     4501 cctgtaatag aagacttagg aagtggagtt tttatagatt tatcaaaata cggtttatct
     4561 tatgaaccaa ctgtattgga ttctattcga caaggtgcag atgtagtaac ttttagtgga
     4621 gataagatgc ttggaggtcc acaagcaggt attatagttg ggaaaaaaga gtatatagaa
     4681 aaaatgaaga aaaatcaact tactagagca cttagagttg ataagcttac aatatgtgct
     4741 cttgaagcaa cattgagaat gtatttagat gagacaaaag ctatagaaaa tatacctact
     4801 ttaaaaatgt tgacatataa aattgaagaa ttagaagtaa aagcaaataa actatttgaa
     4861 aaaataactg ctttaaactt aaatgcaaac ataaatatag aagatggatt ttcacaggtg
     4921 ggaggagggt ctatgcctct tgaaactata agtacaaagg taatatcaat aactcctgaa
     4981 catatgaatg tttcatcttt agaaaaaaaa ctaagactta gtgaagcaca tataatagcc
     5041 agagtgtatg ataataaata tgtactagat gtaagaacta tatttgatga tgaatttgat
     5101 gtaatagttg cggaattgag aaaagcattt aattaaaaaa tagctacaca cacttgtgac
     5161 tttagtcata gcaggtttag agggggcaaa aaatgaaaaa tgtagtaatt ggaacagcag
     5221 gtcatattga ccacggaaaa actactctta taaaagcatt gactggaaga gagactgata
     5281 cgttagatga agaaaaaaag agaggtattt caataaactt aggatttact tattttgatt
     5341 taccaaacaa tagaagagct ggaattgttg atgtcccagg acacgaaaaa tttataaaaa
     5401 acatgttagc tggagcatca ggaattgata tagttttact tgttgtagca gcagatgaag
     5461 gggttatgcc acagacagtt gagcatttag atattctaag ctttttaaat atcaaaaatg
     5521 gaatagtggt tctaactaag tctgatactg tagatgatga atttagagag ctagtaaaag
     5581 aagatatttg tgaaaaaata aaaggaactt ttcttgaaga tgctgaaata attgaagttg
     5641 attctatatc taaaagaggt atagacactc ttattgaaaa aatagataaa atgagtgatg
     5701 atatagaaga taaaaatgaa aactctccag caagacttaa tatagacaga gtattttcaa
     5761 taaaagggtt tggtactgta ataacaggca ctttaataga aggaaagata agtatagaag
     5821 atgatttggt tatatatcca caggtattaa aaacaaaaat aagaagtata caagttcatg
     5881 gagaaaataa agatacagct tatgcaggtc aaagaacagc aatcaatata tcaaatgtaa
     5941 aagtggatga tataaaaaga ggagatgttt tagctgcacc aaactcattg gaggaatcaa
     6001 tgatgttaga tgtaaaatta tcattggtaa atcatttaga taaaggatta aagcactggg
     6061 atagattaag attgtatcat ggaactagag agatactttg tagagcagtt ccactagata
     6121 aagaattaat tgaaagtgga gaaagtggct atgttcagtt gagacttgaa gaaagcatag
     6181 tatctaagaa aggtgatacg tttgtagtga gacgttattc tccaatggaa actataggtg
     6241 gaggtgtaat aattgaccca tctcctaaaa aacataagaa atttgatgaa aaagttatag
     6301 aagcattaaa aataaaagaa aaaggcgaac taaaagatat aatagaagag tacttaaaaa
     6361 ggaatttaaa aaattatcca aatataaaag aaataatgag ctatagtggt gctcatgaag
     6421 aagatgtaaa aagagcgctt gaaacactta tatcagaaga taaagtattt attataggaa
     6481 atatgtatat gcatataaat caatacaata aattaaaaga aaatacaata aagcttttaa
     6541 gtgagtacca taagaagtat aggcttagaa aagggatact aaaagaagaa gtaaggtcta
     6601 agatagagag taattttaag actagggaga tggatatttt attagaaaaa ttgtctacag
     6661 aaaatgctat aaaaatagaa aataatatag tatctctatt agattttgag gttattttaa
     6721 atgataagca aaaagaaata gcaaaaaaaa tagaaaaaag attaaaatca tgtggagttt
     6781 cttctatact gacaatagat gaagtttctg aaggaaatca taactatgct gaagtattgg
     6841 agtcaatgat aggtaataaa gtagagaaat tagatgattt gtatataatg gacaaagata
     6901 tttatgaaaa tgcaaagaac attttgataa attatataaa agaaaataaa gaaataacat
     6961 taggagaata cagagatttg attgattcta gcagaaagaa ttgcatgatt atattggaaa
     7021 acttcgatag aaacaaaata actaaaagag tagaaaacaa aagaattttg ttttagcaga
     7081 aaatgtctgt ttttgcttta aggtataaag aaggaattat aatgtcgagt atcgtataat
     7141 taattagtat aaaatattaa ttaagaggaa gtgtaaagta ttgaagaata taatacctga
     7201 tgtaaaacca gatataaaag aaagagaaga catgagcctt ttatttataa taatgggctc
     7261 agtactttta ttatttatta taaaagatat agagaaatat gaaactttat tacatgccat
     7321 atatacgata tttttagtag ctacaggagt aattatattt aatactacaa aatttaaagt
     7381 agattcattt tctacatttt taggattaat ttttatagct actggagtat tggagtgtat
     7441 atatttattt aattccttgg ggattaaaac taagtctata atggagatta acatcacaat
     7501 atcagcaata acagatttat ttcctatact gggtgtatac ttaagtttta aatttgttaa
     7561 ggataacaaa caaatttatt caagtgtaat tttatttata gcaactgcta cattaacaat
     7621 aacatcttta ttcataatat caggaatttg tgactatctg ggaaatggta aatcacaata
     7681 tgctttagga gttataatat ctatattcat aataattatt tctatcatta gtggaattga
     7741 attaaattca agttcaaata aaggtaaatg ggaatatgat gaaaaaaaga tttttaacag
     7801 aataatagta ataataatct tatcaagagt tccaaatcta ttgcatatag ttattgataa
     7861 tagaaatgta gagaggatat tatcacagat aataataaat gtagccttat attatttata
     7921 taattacata gtatctaaga atattaagaa aacagcactg gaattgcatg atacgaatga
     7981 agaattaaca aaaaaaacgg aaagtttaaa agaaaagaat aaaaaattaa tctatgagac
     8041 agaaaagata gaggaactta agggaatact tatgaaaaga gaatctaggc tacaatctac
     8101 attagatgta gcagtaaata gcatagtagt atttagcaaa gatggagaaa ttacatatgc
     8161 aaataagagc tttagaaata cttttggaga ctataaagaa caagataaat tgactgataa
     8221 aataaaaaac ttcaatgatt tgatagaaag cattcattat gtgtttgttc atgagaagaa
     8281 tgcagagaaa cttattagta caagcgataa taaagtttat caagctatat ttgcaccttt
     8341 aattattgct tcacaaacag aaggagtatt gtgtgtacta gaagataaga ctaagaaaaa
     8401 ggagtacgaa cgcaaactta ttgaagcaaa taagagaagt aaagattttt tagaaagtat
     8461 tggagatggc atagtagtgc ttgaaggtaa taacaaaata tatgttaata atgcatgtag
     8521 ggaaattttt aaaaataatt tagagagcat tgatttttca ttagtatgta aaagtgaaga
     8581 aagtatagaa aaaagatatg taatagatgg tgaagtaaag tatgtagaga tgagtttttc
     8641 tcagtatact aatgctggta ctaataaaac tattattgta atacgtgata caacctctcg
     8701 aaaaatatct caaataaaac ttgaggaaag tcaatcatca tattcaagat ttatagatat
     8761 attacctgat ggcatatgct tattaaaaga agatttaagt ataaactatg caaataagtc
     8821 gtttttagat atgctagctt ttacaaacat agatgatata aaagattcta atattaaact
     8881 attaatgaat gcgaatactg aagaaaaaat gaaatttacg gataatatgg ctaaagtttt
     8941 aaatgaaaat agaagtatac ttttactgga atatgaattg ataaatagtt atgatgatat
     9001 agtagaagta gaattaagtg cattaccttt tgctatatac aatactagat acataatgct
     9061 tattataaaa gatttagtac ataagaaata ttccgagcaa gcagaaaaag aactgcttga
     9121 aagatttaaa acagataaaa tcaaaacgga gttttttgca aatatgtctc atgaattaaa
     9181 aaccccacta aatgttatat ctagttcaaa tcaactggta gattctttct atagaaatga
     9241 aaagataaaa gattacaata acaatattaa atctcatgtg gatttagtta gacaaagttc
     9301 ttataggctt caaagattaa taaataacat tatagattta acaaagatgg agtctgggtt
     9361 ctatacacta aaacttgcga aatacaatat tgtatctgta atagaagact tatttatgaa
     9421 tatagaagag tatgcactta gaaaagacat aaaaattctt tttgatacag accttgaaga
     9481 aattaatgtt tatatagaca aggttgaaat tgagagaatt atgttgaatc tattgtcaaa
     9541 ttgtattaag tttactgata atggaggctg gatatatgta agtattcatt ataaaataga
     9601 taaagtaatc ataagtgtaa aagacactgg agttggaata ccacaagata aattagaatt
     9661 gatttttgaa gaattttcac aagttgataa gactttatcc agaaatactg aaggaagtgg
     9721 aataggactt gctatagtta agaatctagt aagtcttcat ggtggagata tagaagtagt
     9781 aagtgaagtg aataaaggca cagagttctt agtttcactt ccaatgaagg gatttagtag
     9841 tgaacattac acagaagata agagaatata taatattcaa gaaaaaataa aaatagaatt
     9901 ttctgatata tattattaaa aatgattatg agcaaaaata aaataaaaat actatttgtt
     9961 taaatattta agttgtaaga aataggctat cataaggtaa attattatga tagcctattt
    10021 ttagctaggt tttatatcta tatgtgagaa catataatct ctaaattacc ttcaaaaata
    10081 aaatctccaa agtcgtttgg cagtataaaa tgcataccct tttttaaatt atattctaca
    10141 gaattgtgta taagttttcc atttccatcc aacacactgt ataaagaaaa aggtgtattg
    10201 tgtgtaaaat tacattttcc aaaaacatct aatttataaa cactaaaaaa ttcgtttgac
    10261 acaaatgttg tgcatttaaa gtctgatgtt gatacgattt tatagtcagt atcgaaattt
    10321 atatgaggaa cattcgtaac atctattgat ttttgaacat gaagttcacg cttattacct
    10381 gaattgtcag ttctatcata atcatagact ctataagtag tatctgagtt ttgttgagtt
    10441 tctaaaatca atgttccttt acatatagca tgtatagtac cacttggaac atagaaaaag
    10501 tctccctttt ttatattaac ctttctaagt agtttgtccc attcattatt atttaccata
    10561 tttacaaatt ctttatgaga ttttgcatta tgacctatta taatttctgc atcatcagaa
    10621 caatctatta cataccaaca ctctgtctta cctaactctc cattttcatt ttttttagca
    10681 tattcatcat ttggatgaac ttgaactgat aaattatcat ttgcatccaa tatttttgta
    10741 agtaaaggaa acttatcacc aggtgtgttt ccaaataatt ctctattttt attccacaat
    10801 tcagatagtt ttttaccttt atattttcca ttttctatta agcaatctcc atttttatga
    10861 gagcttatag cccaacattc accagttgtt ggcgaatcta tttcataatt aaatttatct
    10921 ttaagtgcag taccacccca tattctatcc ataaaaatag gttttaaaaa taatggttcc
    10981 ataattctgt tcctcctatg atattaaatt tatcctacaa ataattatat ataaatagat
    11041 tataaaatca atagtaaaaa agttttgtcc cttgaaatga cataaagtat aaggagttat
    11101 taaataagat aaactatgat atataatata aagttctaaa ttggagtgat aattatggag
    11161 ttgtttaagg cagaaagcaa aaaatatgaa aaagaatttt taaaattatt ggagcaatgg
    11221 gttagtatac cttcatttta tgatagaaaa actgtatcta aagatatgcc ttttggaaaa
    11281 ggagtatatg atgcattaaa ctggtttgaa aatctaggta gagaaaacaa tttcaaagta
    11341 aaaaatatag ataatcatgc tgttcaaatt gaatatggaa atggtaaaga gtatgtagat
    11401 atatttggac attgtgatgt tgtaaatcca ggtgaaggat gggatagtga accatttaaa
    11461 ctaaatatta taggtgataa attagttgct agaggtgtat ctgataataa agggcctatg
    11521 atagtgaatt ttttagcact aaaaatgata aaggatttag atattaattt aaaaagaaag
    11581 gttagattaa tagctggggg aaatgaagag agtggattta aatgtataaa gcattattat
    11641 agcaaagagc catatggtgt atgtgggttt actccagatg ctaaatttcc tgtattaaat
    11701 ggagaaaaag gtggagcaat aataaagtta atttcaaata tagacgataa atctttatat
    11761 ataagtggtg gaatagagtt taatacaata ccagataaag tttatataaa gaatgtagaa
    11821 aaattgggta aagataatat atgttttgat attaacaata tatcgataaa ttatgataat
    11881 ggcaattata ttgtgtatgg aaaaggtggt cattcatcta aacccgaaaa atcaataaat
    11941 cctatattag ctacaattaa acttttgtca gaaaatattg atgaaaaatg gacaaaagat
    12001 ttatataagt tgataaatca agataatata aatggaaact tatttggttt aaatattgag
    12061 gggaaatgtg ggattttatc aatggtgcca acaataataa atatagtaga tggaaaatta
    12121 gaagtagttt taagcgttag atatccagaa atattaaccc ttgaagatat aataaaaaaa
    12181 tttaatttgt atatggagca aaataatatt aataaatttg agcttattgg ggaaaattta
    12241 aagcaagcaa attatataga tagaaattca aaacttgtaa gaagtttgca tgatatatat
    12301 ataaagtatt ctggagattt aaaaaatgat gttagagtaa ctagtgcagg aagttatgct
    12361 tctgaaatga ataattcagt aatatttggt tgtgaatttc ctgatggtag ctttggcaat
    12421 gtccatagtg cgaatgaatt tgctagctta gatagattta taactgcaat aggtatatat
    12481 gcagaggcaa taattacatt atgtaataaa atataaatac aaaatgtccc ttatatagac
    12541 atattatata tacaattaaa attttacttg atatataatt gaaatcaaag agaaggtgat
    12601 acaatgataa ctaagaaaca tgcaataata gtaaagagtt taagcaataa agatggatat
    12661 atgacatcaa acgaattagc tatcaaattg gatgtgtcta ctaaaactat taaaagatat
    12721 atagcagatt taaatagtgt tttaagcaag tatgatttgg taatagcttc ttctagaggt
    12781 ataggataca agttaagcgg ttctaaaaac aatatagcca gagctattaa agaagcaaat
    12841 aaatatattg atggtttttt agatgattct gaagagtcaa gaatgtcaaa tataatatgt
    12901 atgcttatta atagaaatta tatgagtata gaagcaatgg cagaagaatt aaatctaagt
    12961 atagccgcta taaataaatt gtctagtaag cttaaaagaa aacttgaaaa gtatgactta
    13021 gttataaaat ctaaacctta ctatggaagc tatatacatg gtgaagaaat taatataagg
    13081 caattaatta ctgactatgc aataaaatta gatgaaaaaa gtaaagtgaa ggtgttttta
    13141 gatgacatta gtgaaaacga tatacactgt atagaaagta ttttagaaaa gcacttaaga
    13201 gaaaaagata caataatttc agataaagat tttaatcttt tgctttcaaa aataatcgtt
    13261 tctgtattta ggagtaagag aggtcatagt aacaatataa acttaatgga tacaagttat
    13321 agatttcata actactactt tatagaaaat ctaatgaaag aaatatctga taaaattgga
    13381 tttaaactta ttgaagatga agtaatttat atttcaaatt attctggtgt aatagcctat
    13441 aaaggtacac aaggaagaaa aaacacaagt gaaattgagg aacgaataag tagtgttata
    13501 agtagtgcac ttcaagatat attccttatt tcaggtagtg attatacaaa agatgatgag
    13561 tttatggttg caatctctga ccatataaag agatttttaa atagagctag agctaatgta
    13621 aaatcaaata atcctttgct tcatcaaata aaagagaagt ttcctatagc ttttaattta
    13681 gccgtgtttt tatcaaataa actagaaact gagtttaatt taaaacttga tgaagatgag
    13741 cttggatata tagctatcca ctttgctgct tcaaatgaaa gaatgaaaaa aaatactagt
    13801 aagaaaattt gtatagtttg tcattatggg ataggaacag gacaacttat ttctgaaaag
    13861 ctaaaacaga atataagtga tttaagtgtt gtgggtgttt atccagttag atatctagat
    13921 atggctataa gtcaagatgt tgatttgata gtatctaccg ttgaattaaa aggatatgaa
    13981 aaacctgtct tatatataga aaatatattt gatgatagct taattgaaaa cgtaaacaaa
    14041 gccttttatg aaaaggaaga aagaagaaag ataataagta acatgtttga tgaaaaagct
    14101 tttttcagta taaaggctag tactaaagaa gaggtcataa tttcactttc aaataaacta
    14161 aaagaaagag attttataga ggaaagttct ataaaaagta taatagatag agaaaatatt
    14221 tcatcaactg aaataggaaa tctagtagca ataccccaca caatagtgaa gggagataaa
    14281 aaatctataa taggagttgg aatacttgaa aatccaataa tttgggataa gcaagaggtt
    14341 cagctagtat ttatggtatt ttttaatact aaagaaaaac ataatttctc gatatttaaa
    14401 tacctttata attttataaa agatgaaggc ggagtaagag gaattattaa aatatgtgac
    14461 tttaataaat taatggcact gataggtaat taaggaggaa attaataatg ggaacaaaca
    14521 tatttaacaa agaatatgta tttttaaatg ttgatgctaa gtcaaaggtt gaagttttaa
    14581 aatttatatc aaaaaaagct aaagacttaa acttggcaga aggtgagagc ttagtatatg
    14641 aaggtttaat ggctagagaa gaacaattta ctacaaattt aggagaatct atagcaatac
    14701 ctcacactaa aaatgatgca attgaaaatc cagcagtagt agtattgaag tttaatgaag
    14761 atgttgtttg gaatgaaggt gaggataagg ttaaattagc aataagctta cttatgccag
    14821 gaaaaagtaa agagaatatt catcttaaat tattatcatc tctttcaaga aaattaataa
    14881 ataaagaatt taaagattct cttttaaaaa gtgataatgt tgaagaaata tctaacttaa
    14941 taaatgaagc tttaggttta taattaaaca ctaaggttat aaaataaaaa aataattaac
    15001 taaaaatagg aggaatttga aatgaataaa aaattagtag cattatgtgc ttgtccaatg
    15061 ggactagctc acactttcat ggcagcagaa gcaatagagc aagcagcaaa ggcattaggt
    15121 tatgaagcaa aagttgaaac tcaaggtgct gatggtgtac aaaatgagtt aacaagagat
    15181 gatatattag gagcaactat gataatacat gcagtagcaa taacaccaga aggtatggaa
    15241 agatttgatg gttgtgaagt ttatgaagtt gaattacaag aagctataaa aaatgcagaa
    15301 ggtgttataa aagaaataga agaagattta ggaatataat aaatttattg tggaggaaat
    15361 agaatggcaa ttaagaaaaa agttataaac agttcaggtg cttctacaac aggaggaaat
    15421 aatgtaggaa aatctactcc atctagtcca actcaatcaa agggaaatgg aaaatggaaa
    15481 gaaataagta aacatataat gacaggtata tcatatatga taccagtttt agtaatgggt
    15541 ggacttatag gggccttatc tcaattaata ccatatgcta tattaggact tgacccatct
    15601 gtaggtatag ttgatgctat gaactcagga gaatttacag ggttcaagct tagtctttta
    15661 aatatagcac aattaatgtc aaatttcgga tttactttgt ttggatttgc gataccactg
    15721 tttgcagcat tttgtgcaaa ctctataggt ggaaaaacag ctttaattgc aggatttata
    15781 ggtggatata tagctaataa acctgtaggt gtaccacaat tcgttgatgg acaatggact
    15841 gaagttgttc cagttgcatc aggattttta ggtgcaatac taatagcatt cataatagga
    15901 tattttgtaa aatggttaaa taaatctata aaagtttctc ataactggtt agcttttaaa
    15961 acaacatttt taataccatt aatagcgtca ttagcttgta tggtattgat gatatttata
    16021 ataactccat ttggtggatt aattaatgaa agtatgaaaa acttcttaac agcagcagga
    16081 gcagctggag aatatgtata tgcaacagct ttggcagcag ctacagcatt cgacttagga
    16141 ggaccaataa ataaagcagc aggattcgtt gcacttggtt taactacaga gaatgtactt
    16201 ccaataacag caagaacaat agctatagtt gttcctccaa ttggattagg attaacaaca
    16261 ttattagata aaagattagt aggaagaaga gtatatgata gacaattcta tcaagcagga
    16321 aaaacttcta tattcttatc atttatgggt atatctgaag gagcaatacc atttgcactt
    16381 gagagaccag gttttgttat acctttaaac atagttggaa gtgtaatagg agctattaca
    16441 ggtataattc taggagcaat tcaatggttc ccagagtcag ctatatgggc atggcctcta
    16501 gtagataact tatttggata tataataggt atagcagttg gtgctatatt catagcagta
    16561 ggaaatatat tctatagaaa taaattaata aaagatggta aacttgttgt agattatatc
    16621 gactagtatt taatttttac tatctataaa taactttggc tggtaatatg gttttaatca
    16681 atattaccag ccttacctat atgattaatt aaaggcggtg gagataagat atggataaga
    16741 tagaaaaagt aagagagtat tttagagaat atgatataga tggatttctt ataaatagtc
    16801 ctacaaacaa gttttatgtt ggaaatttat ttagctcttc aggttatgtt tttataacta
    16861 aagaatcaca atatataata gtagatttta gatattttga agaaattaaa agaaaatcta
    16921 gtttgtttaa tgtagtatta atggacaaaa ctagaactca ttttgatata attaatgata
    16981 tttgtagaga gcagaatata aaggaaattg gatttgaggg aaatgaagta tcttttgatt
    17041 tatatagaag tatgagtaat aagttaagtg caaccttaaa atcagttgat ttatctacat
    17101 taagggaaac aaaaaatgaa gacgaaataa aatatataaa aaaagcttgt gaaatagttg
    17161 atgctacatt ttatcatata gtagacttta taaaggttgg tatgactgaa aagcaagttg
    17221 aaaatgaaat tgttagaatt ataaaagatt taggtggtca aaaagaatct ttcgatacaa
    17281 tagttgcatc tgggcttaga ggagcattac ctcatggaaa agcaagtgaa aaagttatag
    17341 agtatggaga ttttgttacc tttgactttg gtgctaagta taataattat tgttcagata
    17401 ttaccagaac catttgtatg ggtactataa ataaagagtt agaagaaata tataatatag
    17461 taagaaaagc taatgaagag tgtataaggg ttttaagacc gggaatgact actggagaga
    17521 tagataaagt tgcaagagac ataattggtt catatggata ttctggtaat tttggtcata
    17581 atctgggtca tggtgtagga attatggttc atgaatatcc tgcattagct cctgaatcaa
    17641 atgaagtatt aaaagaagga atgattgtaa ctatagagcc tggtatatat gttccaagtc
    17701 ttggaggcgt aagaatagaa gatgatgtac ttataacaca agatggatgt atgagattga
    17761 ctacatctac taaggattta atagttgtaa gctaaaaata aattagataa atattttata
    17821 acaataagaa aagaagaggt aaatttaaat gtataatttt gatgataaac cagatagagt
    17881 aagtgaaaag tgtagaaaat gggatttaaa tattataaga gataaatttg gagatattag
    17941 agaagatttt gtaccaatgt ggattgctga tatggatttt aaaataccaa cagaaataga
    18001 aaacaaattt attgaagctg taagaagagg tgtatttgga tatacatact gttatgatga
    18061 attttatgat tcagttattg gttggcaaaa aaatatgcat gaggtaaatg tagaaaaaga
    18121 atggattaca ttaacttatg gaactgtatc aacacttcat tatgtagtac aagctttttg
    18181 taagaaaggt gatagtataa tattaaacac accagtttat gacccctttg aatcatcagc
    18241 aaaaaaacaa ggtgtaaatg taatttgtaa tacattagat gttgtaaatg atagatatta
    18301 tataaatttt gataaattag aagttcaaat taaagaaaat aagcctaaat taatgatgtt
    18361 ttgtacacca cataatccat ccggaaggat atggacaatt gaagaaatga caagggtagc
    18421 aactatatgt aaagaaaata atgttatttt ggttgcagat gaagtacatg cagagcatat
    18481 tcattatggt acatttaatt caatacttaa gattggaaaa gagcttttag aaaatgttat
    18541 tctattgaca tcaccaaata aaggatttaa tcttggtgga ttaaagactt cttattcaat
    18601 agttataaat aaggatataa gggacaaatt tagaaataaa ttaaagcaaa attctataac
    18661 ttctccaaat gtgtttggaa taataggatt gataaccgct tataatgaat gtcatgagtg
    18721 gttaagtggt gtaaatgaat atataaaatc aaattatgaa cttttagaaa cttgggtaaa
    18781 taaatataat aagataaaat tgatgaaaat ggaatcatct tacttagctt ggatggatat
    18841 aagtggatta ggtattagtg caagtgagtt tacagataaa ttggctatag atacaggagt
    18901 attattagaa gatgggagtc attttgtaaa agatggtgag aagtatgtta gaataaattt
    18961 aggaactcaa aaggaaaatg taattgaagc tttaaataga atggatttat ttttaaagtc
    19021 tttataaaaa tttggttgaa ttagtatttt atataaattt aaactattaa tatggtatat
    19081 acataagtag aatttgtttt agattactta agtatatacc atattttata taaaaattaa
    19141 atttgcatta gtcatgtgat aactatttaa attcatatgt attttgtatg tataatagat
    19201 ataattatta tttaaactta ttgtttattt aatttttcaa tagaaaaaga tttatctgta
    19261 agtttaaaat tatcttttat acccttagtt aagtatactt tcttatcctt agttatgaat
    19321 atagcatcta cattatcaat tttattaatt aaattcatac ctttttcaag accaagacca
    19381 aatgtagaag tggataaggc atcacaatta atagatttat cagagattat tgtaacacta
    19441 cttaaattgt tttcaaaagg ataccctgta aatggattta acatatgatg atatattttt
    19501 ccgttttttt cgataaatct ttcataaatt ccagaagtaa caacagactt atttgtagtt
    19561 tctatgtttc ctatggattc accattttta ctagttgggt cttgaatacc tattttaaaa
    19621 ggtttatcat ttttaccatt ttctaaagta aatatatttc ctcctaagtt tactaaacct
    19681 ttttttacgt cctctgattt taaataggct acaattttat cagcagcata tcctttagct
    19741 atggcaccta aatcaatttt catattttct ttggttaatt ttatagattt atttttttca
    19801 tccaatatga tgttcttata atcaataaga ggcagaagtt tttgtatctc agaatcactt
    19861 ggaactttag ctttatctgt tccaatagcc cataaatttg ataatggacc aattgttatg
    19921 tcaaaatatc catctgataa tttggaatat tgtatagctt cttttacgac gaaaaatgta
    19981 tcatcagaaa ctctgacaaa ttttttacca gcattatcat ttattttaga aacatcactt
    20041 cctggtatat gagtgctcat tttgttgtca atatatctta aaattgaatc acattcattt
    20101 aagattttat cacttttgga ttcttttaca ttaaatacag taacttcgtt tactgtacca
    20161 aggtagtagc tagttttact atatttagta ttctggcttg aactcctaaa aaatgaaaat
    20221 aaaattaatg ctaaaatcaa tatcacaaaa ataaatgtga tttttttctt attcatggta
    20281 tattcctcct atgaaattgt gttattattt tattataaca taatttcata ggaggacaaa
    20341 aaatgaagaa aaaagacatt cttcttattt taggcatttt ggttgttatt acagcatgtt
    20401 atgggataat aaatgttata aattctaaaa atgctggaaa tattgagatt tatgtagata
    20461 ataaattgta taaaactgtt tcaataaatg ccaaagaaga atttaaaata gagaatagag
    20521 gggggtataa catagtaaag attcatgata aaggggttga gatagtagat gcttcatgtc
    20581 ctgataaggt ttgcgtacat actggattta taaacaagcc aagtcaaagc atagtttgta
    20641 tacctaatag agtgagcata aaaataaata caaatgaaaa gaatgataat caagaagata
    20701 taatttctaa ataaaataat aaaaataatt gaaaggaatt ggtgataatt atggttaact
    20761 taggaaacga ttgggatgaa ttattgaaag aagaatttga aaaagattac tacttaaact
    20821 taagaaaatt tcttatagaa gaatataaaa cacgccaaat tttcccaaat atgcacaata
    20881 tatatgaagc tttaaaacac acttcataca aagacacaaa agtcttaata ttaggacaag
    20941 acccttatca tggagataat caagctcatg gtttagcttt ttcagttcaa ccacaagtga
    21001 aaactccacc atctttatta aatatgtata aagaattaaa agatgattta ggttgtttta
    21061 tacctaataa tggatattta atgccttggg cagaccaagg agtgttactt ttaaatactg
    21121 ctcttactgt tagagcgcat gaagctaatt ctcataagaa caaaggatgg gaaattttca
    21181 ctgatagagt aatatctatt ttaagtgagc gtgaagaccc agttattttt gtactatggg
    21241 gaagtaatgc acgtaaaaaa gtagagttga ttgatacaag taaacattat attttggaag
    21301 cacctcatcc aagcccattg tcagcaagta aaggcttttt tggatgtaaa cacttctcta
    21361 agataaatga aattttgaaa aagctaggaa aagaacctat taattggcag atagaaaata
    21421 tataaaagta aaaggtaaca aaatgataac aaaacaacaa taaacaatga cattgttgta
    21481 actaatagaa atatgcttaa atagttgaaa atactatgta tgcatatttc tatttttttg
    21541 tcaagttgac aactcttgaa aaaatagtta caatttagtt acacaaaaaa cacaaataaa
    21601 aaaagaaact tacaaagcag aattttatga agcaaaatat atagtgtaaa aaatcttagg
    21661 gaggaaattt tatatgaatt ttaaaaaatt gagtaatgct aaagtctcgg taatggcagt
    21721 tgttttatca gttggaatat tatcgggata ctctgcgctt aataaacaag taacattagt
    21781 agtaagggga gaagaaagaa ctatatcaac atttagttct aatgtaggag accttttaga
    21841 atctcaaaac attagctatg atgcaaatga tatagtaact ttagatgaaa atacaaagtt
    21901 atctaatgga gataaaatag aagtaattga tgtaaaggaa aaaacagttg tagaaactaa
    21961 agacattcca tttgaagtta cagttgttga agatggctct ttattaaagg gtgattctaa
    22021 ggttaaagaa gaaggaaagt ctggtaaaag tgaattaata tataaagaaa cttatcacaa
    22081 tggaaagaaa gtagaaaagg aatttgtgaa aaaggttgtt aaagctgagc cagtaaataa
    22141 ggttgtaagc aaagggacaa aggtagaaat gcaagtagcc tcatcaaggg gagaaagttc
    22201 aagaagaatg gcttcatcat catctagtag cagtagtagt aacaatggta aaaatatgag
    22261 agtggtagca actgcatata ctggtcacag tataactgca acaggaacaa aacctaagtg
    22321 gggaacaata gctgtagacc ctaaggttat accatatgga actaaagttt atatacctca
    22381 atttgacatg gtgtttactg cagaagactg tggtggagca ataaaaggaa ataaaattga
    22441 tatctacatg aatgattcaa aaacagttta taactgggga agaaaaacta tagatatacg
    22501 tatattaaaa tagttaaata atttatattt ttactggaaa ttatattttg attatataga
    22561 gaagaaactc tttatagatt ctaaaaatat aatttccagt tttttatttt ggatatgtaa
    22621 taaaacaggt aaattttaac catgtataga taaaagctat ttaaattata atttactatc
    22681 atataaatct ataaaaattg ttgcaaagag tcaaaatata tgatattata gatttcgttg
    22741 agaaggattt cattatggga gtggatgggt gccggtgtgc cctctagtct tcaaaactag
    22801 tatgaggggt taagagcctc ttaggtgggt tcgattccca cgcattcccg ccaatatgta
    22861 aaaggtatct tttaattaaa agataccttt ttaaatttgt tttaagataa tttagtttta
    22921 atgatatata atattttgta ttatataatg taaattttat aatactatta ttgttcagat
    22981 aaaagtctag gagagtgaaa agatggaaaa taattttaca acgagaacta gttttctagt
    23041 tggagatgat gggatagaaa aacttaataa ttcaaatata atagtatttg gagttggagg
    23101 agttggtagt tttactgttg aagctttagc aagagctgga gtaggcaata ttactattgt
    23161 agattttgat gatgtagata taaccaatat aaatagacaa ataccagccc tacattcaac
    23221 tgtaggaaga tacaaagttg atgtcatgga agaaagaata ttagatataa atcctaatat
    23281 caatataaaa aaaataagaa gtctttataa taaagatact agtgacgaaa tactaactga
    23341 aagatatgat tatgttgtgg atgcgataga catggtaagt tccaaaatac atctaattga
    23401 aacttgtgaa aaaaaaggat tgaaaataat aagttctatg ggtatgggaa ataaattaga
    23461 cccaactaaa atagtcgtta cagatataca caaaacaagt acttgtcctc tagctaaagt
    23521 tatgaggaaa gaacttaggg atagaggtat caaaaagtta aaagtagtat attctactga
    23581 acaaccaata gaacttaaga agaaagtaat gaatggtaga aaagtaacac ctggtagtgt
    23641 atcatttgtc ccatctgtag gaggtttaat aatcgcatct gtaatagtaa atgaactatt
    23701 aggacaataa gttttaaata ttttaattta taaattttat atacaaattt gaaggctaga
    23761 aggatgaata taaagcaatt ttatattcat acttttagcc tagttatttt atattacctt
    23821 attttatgta gttgtagctt tattttttag attatgtatc tatttcataa ttatattttg
    23881 taaatataat ttctccatca ctataaaaaa caatatctcc tattctgtct gttctataaa
    23941 ttgatacatg gttttgtttt agattattaa taacctccct atgtggatga ccatattgat
    24001 ttttatatcc acatgatatt gcagctatat ctggactaat tttttttata aattctaaag
    24061 atgaagaaga attacttcca tgatgaccta tttttataaa attaatatta tttaatttaa
    24121 aagaatgtaa aatttctttt tcattttctt cttcagcatc acccataaat aaaaaagaat
    24181 tatcattaaa agttaatttg aaaactatag aatttaaatt agattcttct tgtatatatg
    24241 atggacttaa tacatatata tttatattgt tatctatgtt taaaacatca tttttataga
    24301 gatgctgaat agataagttt ttatccgtac aagaatttat tagattttga taagcctcac
    24361 tatcagttga ttgttcaggc atatatatgg agtttacatt aaattttttt ataatattat
    24421 caagacttcc tatgtggtct gaatctggat gagttgctat tataatatca atagttttta
    24481 ttcttttttg tctaagataa ctaataatta tattttcgct atcttcatca cctccatcaa
    24541 ttaatatatt cttatttgtg ggtgtttgaa ctaaaatact atcaccttgt ccaacatcaa
    24601 tcatatgtat agatagtaga gattttttgt cacagccgat taaaagtgat attataataa
    24661 gtattgataa aaaaatttta tttctcaata aaaaatcact ccattcatta catgtttata
    24721 taaatttatg atgggtaata taagatatat atgacttatt atattttata ttttaaacaa
    24781 tataaatgaa attaatacca taataaaatt ggagtttttt atatatacaa aataaaattt
    24841 ttaaaattaa gcaataaaaa aggtaggagg attttatgtt tttcaaagat attgaactaa
    24901 attcaaaaaa agagttagac ccatattttg atttagtaga ttatgaagct tgtgagtact
    24961 gttttagtac tttatatatg tggcaacatg tttataagac aggatattat ataggtgaag
    25021 attttgccgt tttagttggg gaatacgaag gagatagctt ctcaatatta ccacttgcta
    25081 aaaaagataa acttccagaa gttgtagatt ttgtccttga atatttttct aaaaataata
    25141 aaaaaatata cttaagaggt attactactg aagtagtaga gtttttaaaa gaaaaatatc
    25201 caggtagatt tgagtatata gaagaaagag atttatttga ctatatttat gatgcagaaa
    25261 gtttaagaac tctagctggt aaaaagaatc aaaagaagag aaaccatata aactatttct
    25321 taaaagagta tgcaggtaga tatgaagcta aattattaga taaagaaaac tttgatgagt
    25381 gtttagtact aatgaaggaa tgggaaagta ataaggaaga aaataatgaa tttgatgaaa
    25441 gtatggatga tgaattaata ggtatcaaaa agatatttaa ccattatgac atattaaaag
    25501 ataaggtaaa agtgtttggt gtttatgtag atggaaaatt agaagctttt agtataggag
    25561 agcttttaaa tccaaatatg gcattgattc atatagaaaa agctaatccc gatataagag
    25621 gtctgtatcc atttataaat caacaatttt tggtaagtga atttaaggac gttgagtttg
    25681 taaatagaga agaagattta ggtattgaag gattaagaaa agctaaactt tcttatcatc
    25741 cttgcagatt tgttgaaaag tacagtgtta gggaggctta atagactata tggagattag
    25801 gtatgctaaa gaagaagaga tagaaagtat aaaagagatt tggagttatt gttttaacga
    25861 tacggagagt tttatgaagt actattttaa tgataaatat aaatctgaaa atactgtagt
    25921 agctttagat gaaggaaaaa ttatttcttc tcttcagcta aatcagtata agttattact
    25981 aaatagcaag gtatataata tatcatatgt agtaggagtt tctacacttc cagagggaag
    26041 aggagctgga tatatgaaca aagtaatgaa atttacttta aacgaattgt atagaaaagg
    26101 gcaattagtt tctatattga tgcctattga ctatagactt tatagaagat ttggatatga
    26161 gcattgttac gaccagattg aatatactat taacacagat gatttaaaaa attttaagtc
    26221 aagtggaaaa atgataaagt ctaatttatc acaaattgat gatttgatac aaatagatag
    26281 aactttttta aatgaggtta atggtaatgt gttaaaagat gaacattatt atgaaaactt
    26341 atttaaagag attcaaagtg aagatggatt tttatacatt catgaaggaa atgaaaaaga
    26401 tggatatata gtttattttc ttcaggaaga taaaatgttt gtcagagagt tattttataa
    26461 aaatatagat gcccttaaat caatgcttaa atttatatat aatcacaata ctcaatgtaa
    26521 gatagttact atatctactc ctacaataga taagataagg tttatattag acaaccctaa
    26581 agatagtgat ataaaaataa aaccttttat gatgggaaga gttataaatg taaagaagtt
    26641 tattgaagat atagatattg agaaggatat taatagctca tttaatttat taatagaaga
    26701 caagtttata gatgaaaata atggtctatt taaaatttct atacagaata agaaggtatc
    26761 tgtagagcag ttagataaaa aaggtgcaga aaagcctcaa gaagattttg atattaaatt
    26821 agatataaat accttaacac agttatcatt ttcttatata gatgtaaatg aagctatttt
    26881 cttaaatgat ataaaagatg tttcagaaga aacactagaa acacttaatt gtattttttc
    26941 taaaaaaaat aactatataa atgaatatat ataggtagag tacgttaaaa gattttaaaa
    27001 atcttttgac gtattttttt gtttagataa caatttatct tgtttaaaaa ttttctattt
    27061 gaaaataatc taaataatat acttttatat gggagtgatt ataattcaaa taagaagacc
    27121 attattaatt atattaatgt ttgtggtagc tatatcattt atcattacaa ataacacaaa
    27181 aaacgacgaa gaacttaatg ataagataat aactatacaa ggagttgtca aaggaaaaat
    27241 tgaaaagaaa agatacaatc agtacaaggt aggggttttt ctaataaatg attatacaaa
    27301 aaataaaaat ttgaagattg gtcagaaagt taatattaca ggtaaattca aaagtttaga
    27361 taaaatgaag tatgatgatt ttgattatgg aaggtatata aaaagtactg gatataaagg
    27421 tatagtgtat ataaataact ataaaattat tgataaaaat aaactttact ctttaatagg
    27481 ggaaataaag ttttatatta gtaaaactta taggtactta tataagaaaa actcagattt
    27541 tataaattct atactattag cagaagttga aaatttgact gaggaacaaa aagaaatttt
    27601 taccagaact ggaactagtc atgtaatatc tatatcaggt cttcatacag gaatattatg
    27661 tgtaattata tcctttctat taagaggtat aaataaattg tataaattat taatactgtc
    27721 gatttttata actttatatt gtataatggt aggtgcgtct ccatccataa ttaggtctat
    27781 agcatttgtt atgatttttt atttatcaat atttattgat agaaagaaag atggaatatc
    27841 ggcattgtct ctaattggga taattttaat tatgaataac ccctatgtta tatataatgt
    27901 aagttttcaa ttgtcttttt tagctacact ttctatatta atattctata ataaaataaa
    27961 tagtattata aaattaagta tggtatcatt gacaatatca tcaaatatat taactttacc
    28021 tataatttat tatacattta aaggtatacc attgctttca attataggaa atttaattat
    28081 agtaccattt gtgggagtaa taatgtattt aagtattgca agtttaatcg tatttaaagt
    28141 aagtgtagta atagctaaaa ttatatcttt ttttaatagt acatttatag aaagcatatt
    28201 ttttttacta gaaaaaatca gcaatttaag ttttgcatac attaatatag aaaatcctaa
    28261 attttatatt gttgttattt attacatagg agtgtttttt tacatatttt acatagaagg
    28321 aaaagagata aaggagcaag agaatgaatt acaaggatat tataaggaat gtaaaagaga
    28381 aaaactttga aaaaatgtat cttttttatg gaagagagta ttatttaatt gagaatgcaa
    28441 taaaagcatt taaagatagt ctaaacgagg gaatgcttga ttttaattta gatataatag
    28501 atgggaagga aatagtctta aatcagctta taagctctat agaaacactt ccatttatgg
    28561 atgataggaa gatagtaata ataaaagact ttgaactatt aaaaggaaag aaaaagaatt
    28621 ttacagatag tgatgagaaa tacttaatag agcatttaga caatattcca gacaccacaa
    28681 ctatagtttt tgttgtatat ggagatgtag acaaaagaaa atcattagtt aagaaaatag
    28741 gaaacaatgg aattgttttt gattgtgata agctttctga tatggatttg tttaaatgga
    28801 taaaaaaatc ttttgcttta aatgatgtta taatagataa ttctcaaatc atgtatttta
    28861 ttgaacaaga aggatacaga gataagagta gtgaaaagac attatctgat ttagaaaatg
    28921 aaataaataa aataagttca tttgttggta aagggaataa tgtaaccaat gatgtaattg
    28981 ataaattatc tcaaaaaaaa gttgagaatg atatattcaa attaatcgat tatattggag
    29041 aacaaaatgc ttctaatgca atgaaaatat taaatgatat gatacaagaa ggcgaatctg
    29101 tattaggtat attttctatg atagcaagac aatttaaaat aattatgcaa gtaagacagt
    29161 tacaacttga tggatattca acaaaactta tagctgataa attaaaaatg catcaatttg
    29221 ttgtaggaaa agcattaaag caaactaaaa atttttctga tgatataatt gtggaaatat
    29281 taaactatat attagaaagt gattataaaa taaagacagg tcttataaga gatactttag
    29341 cagttgaaat gttggttagt agatactgta aaagagaagc aatttaaaaa atctatatat
    29401 taataaaaaa taaatagcaa gatatgttat agttcagagt agatgtaagc taaattaagt
    29461 ttgatataca atcaactata atatgtctaa ctatttattt tttattgtat aaatttacaa
    29521 aataaaaaac ccctacatag gggttattat atataagaaa tataaactgg taattaagcg
    29581 ttcataccgt ttaatttttg agctaattta gctacttttc tagctgcagc attcttatgt
    29641 atagttcctt tagaagctac ttggtatatt cttttttgag cgtattggaa cttagcaaca
    29701 gcatcctctc tgtttccagc tgcaacagca tcttcgaatc ttcttattgc agtttttatt
    29761 tgagattttc taactctatt taaagcagtt ttcttttcga taacacttat tcttttctta
    29821 gctgatttta tatttgccac cgtgttcacc tccctgtatt tttttatcat attcatcgtc
    29881 aacatattag attttaacag aaataaatct aaaaatcaag gattattatt tatatatttt
    29941 aataatgttt tttattttga ttttttagac tgtaaattgt gtataaataa tttgcaatat
    30001 cttgttttta aattggtata ttttgtgttt taaatatttt gacatatata aattaatatt
    30061 ttatttttgt aacaaatatt ttgagataat acaaactatt aacatacatt ttgatagtat
    30121 ttccaataat tataagataa tacaagaaat tactcatttt tgtaaattta atgaaaaatt
    30181 ataaaaatat aaatttatat gcttaattaa gataattttt ccaataatca agataatttt
    30241 tttcattagt atgtatgata gatgcatcaa acaatataac taatatgtta gaaggttata
    30301 tgtaattaat gtcagtgttt atatagaata gcatttgtag catttattat agttgtaatt
    30361 actatttata tcatagactt gaatagtcta aaaaaataga ctataatatt tttatagact
    30421 aaagaaaggg ctgataagat ggacatagca aaactaattt taaatcctgc aaggcttcgt
    30481 atcttacaat atattcgact tcatggcagt gttcgtacat ctgatattgt aaagtattta
    30541 aatgatattc ctcgtgcaac agtttatcac catgtaaaaa ttttagaaga gaacaatatg
    30601 attgaagtaa ttaaagaaaa tcgtgtgcgt ggtactattg aaaaggttta tgcactaaag
    30661 gaatatacaa catctatgga aggagagacc ttcgttgcac tttctacagc attttatgta
    30721 ggtctgatgc aggaaatgaa tgaatacttt agcagaaaag agcaagacca taaaaaggat
    30781 aatgtatttt tctcttcagc attactatat atgagtgata atgaatatga aaatcttctt
    30841 aaaagtatag ctgatttatt gaaaccatat atagaacaaa agcctaaatc aaatctaaaa
    30901 cttagaaaac tttcaattat atcttctcca cctgtagctg ataatgataa aacaaaataa
    30961 catgcaaccc atttttataa aaggaggtta tatatgaaat ttcatgagtt tggaaataaa
    31021 aacagaccac atattatgtt gattcatggg ggagggaatg catggtggaa ctatttgcga
    31081 caagcagaag ctttgtctaa caactatcat gtgatacttc ctacattgga tggtcatgga
    31141 gaagaatatg aaacaacata catttctaca gaggatacag cagataagtt gatatcatat
    31201 atagatgaaa attgcagtgg acatcttttc gctttgtgtg gggtatcact tggtggtcaa
    31261 attgtcatgg aacttttatc tcgaaaacct aatattacta aaaaagcaat tattgatggt
    31321 agtatttgct acccaagacc tcttatggca aggttttgta ttgctggtat tcgatttttt
    31381 ggaggacttt tgtttagtga gaaggcttgt cgctttcaaa ttgctatgat gccaaaattg
    31441 ttacctgaaa atatgcaata tccagatgaa ataaaagcat attatatgac agatatgcca
    31501 catgtaagaa aagaaacatt ctataatatg tatcgcactt acatgatgaa ctatacactt
    31561 aaagagaatg ttaaaaaaac cacagcacaa gtaatgtact ggtatggaga aaaagaaatg
    31621 aaatgtgtta aaaaatctgc aaaactgttt cagtcttatg tgccttcttg tgagatttat
    31681 gaagctaaga gctataatca tggatattta tcactttatc ttccaaatga atggttggaa
    31741 attgcagaac catttttcca aaaggaataa aggtgttagg tgattattgt ataattattg
    31801 ctgtttttta atatagtaaa taaatcaggt ataaatataa aaaagttatt ttagtcaata
    31861 tattagtgaa agcttaatag gaaaattata aatagattaa aggtagcgcc tatataaata
    31921 gttgctacct ttttctgttt gtaaataaat gatagataag aaggtttact gacaaatcac
    31981 tgactaaacc caattttctt acattgaaag ccttaatttt acttgtttta aataaattta
    32041 caatttcttg ttataaaata ctaaattttg ttaacaatta taattagcat ttaatttata
    32101 ctggaggttt atatgattag tgtaagaaca gatttagctt tagaagctag tgaaatgtgt
    32161 gaaaagtctc aagaaggaag tagtattcct ggtgtaaaaa tagaaactaa agaattagaa
    32221 aattgcattg taactaaagt tgaagtaata gacaggcaag gcgcagagat aatgaataaa
    32281 gatataggaa agtatataac tctggaaagt aatcttatga agtttgatga tgatgagtca
    32341 agagaagaaa tgataagtta tttaaaagat gaattagtag atatatttgg ccaagacgaa
    32401 aataaaaaaa cactggtaat cggtcttgga aatagaaata ttacttctga tgcattagga
    32461 ccaaaaagtg tatccaaaac acttgtaact agacatcttt ttaaaaatta taataaagac
    32521 tatgatgatg atttcactga ggtatcagct ttaagcccag gagttatggg tgttactgga
    32581 atagaaacta gtgaaatagt aaagtcattg gttgagaagg ttaagccaga tagagtagta
    32641 gcaatagatg cattggcttc aagaaaaatg gaaagagtaa actctactat acagatatca
    32701 acagcaggaa tatcacctgg tggaggtgtt ggaaatacta gaaaatctct aactaaagaa
    32761 actttaggcg tggatgttat tgcaataggc gttccaacgg tggttgatgc agcaactctt
    32821 acaatagatg tcttagatat ggcaatagat aatttaatag ctcaatcaga agaaacagaa
    32881 agtttttatg aaatgttgaa aaaacttaaa gaagaagaaa aatatcatct aataaaagat
    32941 tcgttagacc catatgacaa gaacttaata gtaacaccaa aggatataga tgatacaatc
    33001 gaaaatctat ctataataat aagtgaaggc ttaaataggt ctttacatcc aggtagattg
    33061 gtataaaata aggaggagca attatgttta aaaaatgcat taaagtagta accttgactt
    33121 ttatattagt atgcatttta ccaggaaaat cattagcttt gaatcaagat gattttttaa
    33181 agtttttagt aaattcatct tatccagaag ctaaagtcga aggaaatgat acagaaaata
    33241 aaaagaataa taaaaataaa gaaacaagta aggaaaataa ggaagaaagt aaagaagaaa
    33301 acactaaatc taaagatgca agtaaagttg ataataaaaa agagagtgaa aaagaatata
    33361 taaaacttta tgttggtaaa gaaaatgttc cagatattga gtcaaaaaat tcagacacaa
    33421 ctgaaactaa cacaacatct agttcagatt ataaggatga tttaagagta accaaagaaa
    33481 atccaagaat tttgatatat catactcatg gatgtgagac ttattcaaat tcacctgatg
    33541 gaaattatca ttcaagagat aagaaaaatt cagtaatgga agtaggaagt gcactaacta
    33601 gtgctttaga tagcaaagga tggggtgtag tccatactac taaataccat gactatccat
    33661 cttataataa ctcttatgca agtagcttaa aaacaataca aagtatatta cctaaatata
    33721 actcagtgga tatagctata gacttacata gagatgctag ggatttaact aatccagcca
    33781 ctaaggaaaa agaccattta aaatatacaa ctatgataaa tggagagaga gtatcaaagt
    33841 tcttctttgt tgtaggaggt aaaaatacaa atagaaaaca acttagagct ttagcagaag
    33901 atataactgc ttttgctgag aaaaagtatc ctggtctagt atctccaata gtagaaaaag
    33961 actatgctag attcaatcag tttgcagtta agaatcatat gttagtagaa atagggaata
    34021 acgcaacaag tgtagaagaa tctaaggcta ctacaaagta tttagccgag attttggatg
    34081 aatattttaa acaaaaaaat tagagcttta agttataatt aggagcatgc taaatgagcc
    34141 gattagaaaa aaatatagaa agtaaaagta aactaagaaa atacaagtat attatgagaa
    34201 tcttattttt gattactatg attatatgta catcagtttg tgtatttata gtggacagta
    34261 atgcaaaaag tatgctagga atgaaacaat atgattttcc aagtattaaa tttgatataa
    34321 caaaatttga ttttgacata ccaaattttg atatacatga aatcataaaa aaatttaata
    34381 agtagtaata agtgaataag gtttattgat taaaataagc cttattttag ttatatattt
    34441 ttaatgtata aaataaaaat tcattaactg tattttatag gatttacttt aagtttacga
    34501 tattatataa tatttagtgt tagacttgat aatccacata taatgtggat aattttgttt
    34561 agtgccaatt agtttatatt caaaaatttt aaatttggta tataaagagt ttttagataa
    34621 tgtaaaataa taactataag aataatcaag aggagggaat tttaaggtgg acaataaaca
    34681 aagtagaact agaaatttta gtataattgc acatatagac catggaaagt ctaccttagc
    34741 tgatagatta atacaacaaa ctgggcttgt tagtgaaaga gacatgaaaa gtcaattact
    34801 tgacaatatg gaccttgaaa gagaaagagg aatcactata aagcttcaaa acataagatt
    34861 aatgtataaa gcgaaggatg gaaatgaata ttatttaaat cttatagata cacctggaca
    34921 tgtagacttt aactatgagg tatcaagaag tttagctgca tgtgaaggag cactattagt
    34981 agttgatgca gctcaaggtg ttgaggcaca aactttagcc aatgtttatc ttgctataga
    35041 ccaagattta gaaatattac caataataaa taaaatagat ttaccaagtg caagaccaga
    35101 ggaagtaaaa aatgaaatag aagatttaat agggcttgat tcaagtgaag ctcctcttat
    35161 ttcagctaaa actggtttaa acatagaaga tgttttagaa gatattgtaa aaaatgttcc
    35221 tccacctaaa ggagataatg aagctccatt aaaggcatta atattcgatt cttactatga
    35281 tgcttacaaa ggtgttgtag cttatgttag agtatttgaa ggaactgtta aaaagggtat
    35341 gacaataaaa atgatgaata ccaataaaaa gtttgaggta actgaagttg gtgttatggc
    35401 tccaggtcaa actgaactta gtgaattatc agcaggtgat gttggttata ttgctgctag
    35461 tataaaagat ataagaagtt gtcgtgttgg tgatacaata acagattcaa ataatcctac
    35521 agaagaacct ttaccaggat acaaaaaagc tactccaatg gtatattgtg gtatatatcc
    35581 aggagaagga gaaaagtatg agaatgttag agatgctctt gaaaagcttc aagtaaatga
    35641 tgctgcactt gaatatgaag ctgagacttc agcagcacta ggatttggtt ttagatgtgg
    35701 tttcttaggt cttttacata tggagataat gcaagaaaga cttgagagag aatttaacct
    35761 tgatataatt actacagctc catctgttat atatagagtt acaaaaatgg atggagaggt
    35821 tgtaatgata caaaatcctg caaacttacc agaaccatct gagataaaga tgatagaaga
    35881 gcctatagta aaaggagata taatagttcc taaagactat gtgggtgttg ttatggagct
    35941 ttgccaggaa agacgtggaa atatgttaaa tatggaatat atagatgata gaagagtaat
    36001 gcttcactat gaccttcctc tcaatgaagt tgtttacgat ttctttgatg ctttaaaatc
    36061 aagaactaga ggttatggtt ctcttgatta tgaggttaaa ggttatgtag catctacact
    36121 tgtaaaactt gatatattaa tcaataaaga gcaagtggat gcacttagtt ttattgtcca
    36181 tgagacacgt gctttcccta gaggaaaggc aatgtgtgag aaattaaagg gagaaattcc
    36241 aagacatcag tttgctatac caatacaagc tgctgttggt aataaggtta ttgcaagaga
    36301 aacaataagc gctctaagaa aagatgttct tgctaaatgt tatggtggag atatatctcg
    36361 taagaagaaa cttcttgaaa aacaaaaaga aggtaagaag cgtatgagac aaattggttc
    36421 tgttgaagtt cctcaaaaag catttatgtc tgtgcttaaa ttagatgagt aaatccttat
    36481 aaatttagat aaagatattt aaaagctaga gtgattttag aattatttct aaattagtct
    36541 agctttttta tggtatattt taagtaaact catagagaat ataagtaaga atattaaaga
    36601 agaataaaaa ggtgatattt atgattaata tagaaattcc taaaaaagta gactatataa
    36661 ttaaagaatt agaaaagaat ggttatgaag cttatatagt tggaggatgt gttagagatt
    36721 gtttattaga aagagttcca aacgattggg atataacaac tagtgctaga ccagaagtgg
    36781 tagtagaatt atttgaaaaa acaattccaa ctggtataca acatgggact gtaacagtta
    36841 tgattgaaca tgaaccattt gaagtgacaa cttatagaat tgatggaaat tatagtgatg
    36901 gtagacatcc agattcaata gaatttacaa ataacatagt taaggacttg tcaagaagag
    36961 attttactat caattcaatt gcatacaatt caaagacagg attagtcgac ccatttaatg
    37021 gctatgaaga tatacaaaat aagtatatac gttgtgttgg aaatccagta gatagatttg
    37081 aagaagatgc acttagaatg cttagagcag ttagattttc agcacaactc aattttaaaa
    37141 tagctgaagg tactaagcaa agtattcata aaaaagcaga tttgataaaa aatgtttcta
    37201 ttgaaagaat ccagacagag tttaataaaa tattagtatc tgattcatct aaattaaact
    37261 tattaaaatc aacaggtttg ttgaaattta taattcctga aatatgtgaa ttagaagatg
    37321 ttactcaaca caatccatat cacatctatg atgtacaaaa acatacttta atagctacag
    37381 aagtaattga agatgaactg tatttaaaac ttacaatgtt gtttcatgat ttaggtaaaa
    37441 aagtaactaa aacaactgat aaaaatggtg ttgaccattt ttatactcat agtagagaat
    37501 ctgtaaagat tgcaaagaag attttgaaaa gacttaagta tgataattat actattaata
    37561 aagttttaat attaatacaa tatcatgatt atagaataga acctaaaagg aagataatta
    37621 aaaagttatt aaataaactt gaagatgttg gattatttga agatttaata aaagttaatt
    37681 gggctgatac acttgcaaaa aatccaaagt atgcaaaaca aaagatatta aatcttattg
    37741 agtgtgaaaa agaatttaaa catataataa atcaaaagga gtgctttaat cttaaagatt
    37801 tagctattaa tggaaaagat ttgatatcta taggtataaa accaggtaaa gatataggat
    37861 atattttaaa taagatgctt gaaatagtca taaataatcc agagttaaat gaaaaagaaa
    37921 tactaaaaga aaaagcatta aatatatata ca
//
LOCUS       DAEQAF010000032        37865 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.033, whole genome shotgun sequence.
ACCESSION   DAEQAF010000032 DAEQAF010000000
VERSION     DAEQAF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37865
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.033"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(127..1107)
                     /locus_tag="KRN00_001685"
     CDS             complement(127..1107)
                     /locus_tag="KRN00_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane dipeptidase"
                     /protein_id="HBH1827551.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMVVDVSHLNEKSFWDLMSIASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASMPSVDGLESTHTAQNIVVELENRGYKKKDIDLISSGNFYRLFKDILK"
     gene            complement(1164..2366)
                     /locus_tag="KRN00_001686"
     CDS             complement(1164..2366)
                     /locus_tag="KRN00_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBH1827552.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMVGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            2561..3115
                     /locus_tag="KRN00_001687"
     CDS             2561..3115
                     /locus_tag="KRN00_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1827553.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTQKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            complement(3230..4021)
                     /locus_tag="KRN00_001688"
     CDS             complement(3230..4021)
                     /locus_tag="KRN00_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBH1827554.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIYKFKDYLDIDGITNFKVAEDTFFYIVVDFSKFNLESIKEYTNV
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMNGTEEILSNILDESCLLNI"
     gene            complement(4049..5137)
                     /locus_tag="KRN00_001689"
     CDS             complement(4049..5137)
                     /locus_tag="KRN00_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBH1827555.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNISLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKHFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLIGKNDFHGAKFYRHLKDKDESINYIKTIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFVL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDV"
     gene            complement(5191..6429)
                     /locus_tag="KRN00_001690"
     CDS             complement(5191..6429)
                     /locus_tag="KRN00_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH1827556.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWISDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMDSKESLKKEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIGIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            complement(6407..7483)
                     /locus_tag="KRN00_001691"
     CDS             complement(6407..7483)
                     /locus_tag="KRN00_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH1827557.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHSITGILIPKVNSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            complement(7547..8683)
                     /locus_tag="KRN00_001692"
     CDS             complement(7547..8683)
                     /locus_tag="KRN00_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1827558.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            complement(8684..10246)
                     /locus_tag="KRN00_001693"
     CDS             complement(8684..10246)
                     /locus_tag="KRN00_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH1827559.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            complement(10333..13092)
                     /locus_tag="KRN00_001694"
     CDS             complement(10333..13092)
                     /locus_tag="KRN00_001694"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1827560.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            complement(13082..13711)
                     /locus_tag="KRN00_001695"
     CDS             complement(13082..13711)
                     /locus_tag="KRN00_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1827561.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            complement(13797..14375)
                     /locus_tag="KRN00_001696"
     CDS             complement(13797..14375)
                     /locus_tag="KRN00_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1827562.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            complement(14414..14992)
                     /locus_tag="KRN00_001697"
     CDS             complement(14414..14992)
                     /locus_tag="KRN00_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1827563.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            15321..16757
                     /locus_tag="KRN00_001698"
     CDS             15321..16757
                     /locus_tag="KRN00_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1827564.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            complement(16849..18723)
                     /gene="asnB"
                     /locus_tag="KRN00_001699"
     CDS             complement(16849..18723)
                     /gene="asnB"
                     /locus_tag="KRN00_001699"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1827565.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNNLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWYQLFIEHKNVEY
                     "
     gene            18926..19600
                     /locus_tag="KRN00_001700"
     CDS             18926..19600
                     /locus_tag="KRN00_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH1827566.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            19713..20249
                     /locus_tag="KRN00_001701"
     CDS             19713..20249
                     /locus_tag="KRN00_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1827567.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(20415..21035)
                     /locus_tag="KRN00_001702"
     CDS             complement(20415..21035)
                     /locus_tag="KRN00_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH1827568.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(21349..23487)
                     /gene="vanT"
                     /locus_tag="KRN00_001703"
     CDS             complement(21349..23487)
                     /gene="vanT"
                     /locus_tag="KRN00_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH1827569.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFMLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIAFIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKVFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            complement(23505..24311)
                     /locus_tag="KRN00_001704"
     CDS             complement(23505..24311)
                     /locus_tag="KRN00_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1827570.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            complement(24308..25408)
                     /gene="vanG"
                     /locus_tag="KRN00_001705"
     CDS             complement(24308..25408)
                     /gene="vanG"
                     /locus_tag="KRN00_001705"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH1827571.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPILHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            complement(25678..26751)
                     /locus_tag="KRN00_001706"
     CDS             complement(25678..26751)
                     /locus_tag="KRN00_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1827572.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIV"
     gene            complement(26801..27502)
                     /locus_tag="KRN00_001707"
     CDS             complement(26801..27502)
                     /locus_tag="KRN00_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH1827573.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            complement(27936..30467)
                     /locus_tag="KRN00_001708"
     CDS             complement(27936..30467)
                     /locus_tag="KRN00_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH1827574.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            complement(30575..31192)
                     /locus_tag="KRN00_001709"
     CDS             complement(30575..31192)
                     /locus_tag="KRN00_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH1827575.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTTDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            complement(31554..32438)
                     /locus_tag="KRN00_001710"
     CDS             complement(31554..32438)
                     /locus_tag="KRN00_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH1827576.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            complement(32629..33879)
                     /locus_tag="KRN00_001711"
     CDS             complement(32629..33879)
                     /locus_tag="KRN00_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1827577.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYENSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVGYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            complement(34101..34865)
                     /locus_tag="KRN00_001712"
     CDS             complement(34101..34865)
                     /locus_tag="KRN00_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827578.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            complement(34859..35584)
                     /locus_tag="KRN00_001713"
     CDS             complement(34859..35584)
                     /locus_tag="KRN00_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827579.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            complement(35586..35954)
                     /locus_tag="KRN00_001714"
     CDS             complement(35586..35954)
                     /locus_tag="KRN00_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1827580.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            complement(36130..37674)
                     /locus_tag="KRN00_001715"
     CDS             complement(36130..37674)
                     /locus_tag="KRN00_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1827581.1"
                     /translation="MRNLQKKLMFFLFICIILQITYTTPVYSLCKLYKNNSINNFESI
                     VSNNQLISKHAIQIILIMAIICVILIFYIIYDKLNFKIKLQRIAYTDNLTGANTIDKF
                     VIDANKILCKNTQVKYALLYIDIDKFKYINDLFGYEVGNEILRNLTKIIKSNIFEEEM
                     FARISADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLSCGIYFILPED
                     RDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFSSLENKEFIIY
                     LQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLDLYVLEEVCIY
                     LRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIELELTESIIFDN
                     FDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFIMETYNSKRSK
                     IIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPMPIEEFEHLIV
                     SNLVRG"
BASE COUNT        12710 a         6563 c         3935 g        14657 t
ORIGIN      
        1 aatgttacta gaattgaaac ttctagtaac attaaaattt aatttaataa attatgaaca
       61 ccaatttaaa tatgtagata ttattgtata aatataatat tttataaatt taagttcttt
      121 attatattat tttagtatat ctttaaagag cctataaaaa ttaccactag agattaaatc
      181 tatatctttc tttttataac ctctattttc aagctctact actatgttct gtgctgtatg
      241 tgtgctttca agaccatcta cacttggcat actagcgttt ccagtaaaag aacctatagt
      301 ctctttccct aagtaatcac taaaatcaaa accaaaagat acatgttcta tacctataag
      361 atttaccata tagtctatat ggtcaaccaa atgtattaaa tcttgcttct taggattact
      421 attagtaaat cctctaaaac tatttattcc aactaatcca cctgtatttg aaatttcttt
      481 taattgatta tctgtaagat ttcttttagc atcacataaa ctcctagcat tagaatgaga
      541 agctataact ggcttacttg caatagacat taaatcccaa aatgattttt catttaaatg
      601 tgacacatct actaccatgc ccaatttttc cattttattg actgcttttt tacctatttc
      661 agttaaacca cgattttcat cccctaaaca tcctgtagca agttcattct gttcattcca
      721 agttaatgat gcatgtcttg caccaacttc tttataaaaa taatctagta aatctatatt
      781 tcttccaata tggcttaatc cttcaagacc aattaaaata tttattttgt tttcacttat
      841 acctttatct atatctgaat atttttttac tatatttaca acatctttca tatcttcaat
      901 ttcatctttt atagagctta taatttgttt aactcttttt tcaggctctt tatcatatgg
      961 ggggtctatc catattacaa aaatagctcc ttctatattt gctcttttaa aattatcaag
     1021 atggattctt ctaaatacat ctttttcccc gttaagcctt cttattgtta catctgccca
     1081 agtatctgaa tgtccatcga aaatcataac aacctccaat taaataaaaa tctttctaaa
     1141 aaacaacttt ttttcacgta aacttatatc aaaatatttc ctaccaaaag gccaaaataa
     1201 ttaccaacta tatatccaaa tgtccctact ataagtattg gccctactaa cttagaccac
     1261 ccttttgata ttgccatagc tgctgctgtt gtaggtccac caatatttgc attagacgca
     1321 agaatagctt cttctaaact aaacttaaat atttttgcaa ctataaatgt aactagcatg
     1381 tttattagta ccattattcc gcagtataaa agtagtaatg gtgatttttg aattattaat
     1441 gttattgaag caggaacacc cactacaaca aagaatatgt atattaaaaa tgtacccaac
     1501 tcctgtgctc cttttatatc accaaagaaa ttaggcataa atgtggcaaa caacatagtc
     1561 aaagtagtta ttattagata ttgatttcca aatagagtat ttaacattgc taaaaaagga
     1621 tttgataatg gtattatagc tttaaaccaa gttgatagtt ctacagatac tgcaacaatt
     1681 ataaaggcgc taccaatggc tattgctata tcttttaaag atatttcttt tcttccccaa
     1741 taatttgctg ctactgtttc tccttcagtt atacctatac tttccatttc atctacatgt
     1801 ggatgtttaa aatgttttct aaaaaatcca attgatggta tagctattaa gacaaagaaa
     1861 tataatgcca ttaaaagatt atccgctaca actgttgctg atactaattc tcctggcgca
     1921 tcaaatgcac ctgacatagc agcaaagttt acatttccac ctatataaga acctgtcatc
     1981 atagctgcaa caatatttaa atctggtact acatttttta atgctaaaaa tccaaccata
     2041 gctccaagta cagttcctac agaacctaca agaaatatta tgagtaatct tccactttcc
     2101 ttccatatct ttttaatgtt acattgatat aacaataaag ctatggctaa aggaacaaca
     2161 tatccccata cttggtcata tacaacagac tctactggta taatatttag atttgataat
     2221 aacattgctc ctacaagagc tattattgct cccgacactt ttgatgccca attgtacttt
     2281 tgttccaaat aaatactaaa tgctgcccat ccagttacaa ctgcccataa tacccaaata
     2341 ttatcaggac ttacaaaact cttcatctta attacctcca tttcattaaa ttaaaatatc
     2401 attatcaata ttcaatatat tgaatattaa tactattata atgcatcttt tcagaaaatt
     2461 caatataaca taaaaaatac atgcattata aaactttttt ttattttatt aatctttata
     2521 aattatatgt tataatcatg tctgaggggg tttgtatcta atgaatatag atgtcggaag
     2581 caaaattaga tctcttagaa aatctaaaaa tataagtatc tctactttag caaaaaattc
     2641 agatttaagt acaggcttaa taagtcaaat tgagcgtaat atggttgttc catctattgt
     2701 agcaatgtgg aaaatatcaa aagctcttga tataaatata ggttattttt ttgaagagat
     2761 tggaagagag gactctgata tagtagtaaa gaaaaataat cgaaaaaaga tagtaactaa
     2821 tgattctaca aaattttacg aacttcttgt tcctaattta tctgggaaaa aaatagaatt
     2881 tatacttgtt acactagatg gtcatacaca aaaaaacagt gaatttgtga cacacgaagg
     2941 agaagaatgt ggctatataa taaaaggtaa aatgaagata acacttggaa ataaggaata
     3001 tctattggag gaaggagata gtttttattt taacagtact atcccacatg tgtatgaaaa
     3061 ttatgatgat gaggtatgta tctcagtctg ggcaatgact ccaccttcat tttaacatgt
     3121 tgagttctta cttaaatata aattgataaa aatctgaaat aaattagtat gataaacttt
     3181 actataattt atttcagatt tttctagttt attatttata tatcagtcat tatatattaa
     3241 gtaggcaact ctcgtctaaa atgttagata gtatctcttc agttccattc attccattga
     3301 aagaacttga tataaatgaa ttttctattt catttttatt tatatcacca tgcttcaata
     3361 cataggattt atttgagata ttaagcatac catagtccat aatagaatct ccaactgcat
     3421 aaaaatattc tattcctaat tctttagtca agtattttat agcattttct tttgaaattt
     3481 cttttggtat aaaatatatt tttctgccac tcacataaaa cttccaattt tttgattcca
     3541 atacatttgt atattcttta attgattcta aattaaattt tgagaaatca acaactatat
     3601 aaaaaaatgt atcttctgca actttaaaat tagttattcc atctatatcc aaatagtctt
     3661 taaatttata aatcatactt tcaatgggct catagtcaga ttttagttta tctatttttt
     3721 cactccatga tttcaatatt tcattatctt taagtataac tcctccattt gaggttatac
     3781 tccaaggaaa ataaatccca tatttattaa actctatacg cttaaattgc tccactgttc
     3841 tagtagttgt aggtataaac ataccataat attgtatttg ctttattaaa tttatagtat
     3901 ctaaagatat ataagatatt tctttttccc tataaatttc tatattagca tatttactat
     3961 cagcatttaa aaatttattg gagtaaatga tactcctgtc taaatctgaa aaaacaatca
     4021 ttcaatattc tcctgtctaa tatatttcct aaacatcttt catatttttt attattccac
     4081 aacatttata ggcttttaaa tccatttgtt caacttcaac atttttctcc ttagctaata
     4141 cgaatatatg gtctaaagat ttatcattta agtctttaac aagaatctta tacggaactc
     4201 ttctaagtaa aacccttgtc gtttctccta cacctggttt gataaagtta atatctgtta
     4261 tgttatactt ttcttttata tttaaaacat caaagtatcc atctcttgtt ataatatcac
     4321 tttcccagtt ttcaacttca tcagatatgt tcttaaattg atttttaaaa cattcttcta
     4381 tagttttaat atagttaata gactcatctt tatcttttaa atgtctataa aacttagctc
     4441 catggaagtc atttttacca attaaatcct ctcttagtac agttctgctt actagaccag
     4501 aaacggttga atttaaacat gcacttggta ttaagaaatc ttctctaatt ccataaagtc
     4561 ctgaatatcc agcagggtca gctaatacag caagtgttga gtcaaaatgt tttttaaatt
     4621 taacattaag ctcatcacat gctttttcaa gttcttttga tatagttcct ttaccagtcc
     4681 atccatctaa aaattgaatt tttgagctcg gatgattctt tactatatat tcaattgcat
     4741 tcatatctat tcccttatct cttattatag agattgtata gtgaggtaaa cttatattat
     4801 acttgcttct tatatatctt tttgccaaaa taccaatagg tgttcctgct ctagcaagcg
     4861 aaactagtac tacatcattt ccattttttt taattatttt ttcacacata acgcctatag
     4921 aaaatgcaag cttatcttta ttttctctta gtttctcatg atataaattc agataatctt
     4981 cactaacttc atactctatt ggtatcattt ctgaataatg tctaccattt tgtattttta
     5041 attctctttc tttatttcct tcttcttcaa ttaaatttga tatatctttt aataaaaaaa
     5101 taacatcatc tttagaatac gtgctaaaat ctctcatatg actcaactcc tatcttaaaa
     5161 tcgcgatata ttttatcctg ttaaaacact ttagctacaa catactatag ttaattcttt
     5221 tatacttgtc tttttaatta tatcaataaa ttctagataa gaattttcac ttttatttag
     5281 ctctacaaat aaataacact tagaaaaatt atgtttatct atattgtaaa tataattttg
     5341 aatacctata ttataaaaac tctttagcat aaatttactt ttaataggat aattattctt
     5401 atcaatatta ataattggac ttcttgttgt tgaatgatag tatatatcat attgattttc
     5461 tttttctttt gcaaacagca taggtatata cataaattct tcagtaccta aaaatagaat
     5521 cttttctttt tcttttttta aagattcttt actgtccata gttatttttt tactttctct
     5581 cttaacgatt tcttttaatc taaattgttc tcttctatta attccaaatc ttcctgtata
     5641 ttttacatat ttcttatttc caatataatc ttctaaatca acataaatat gatttactac
     5701 taaatttact ttatcacttg aaatagtctc taatttagta atactataat tgtcgttgta
     5761 atttgaaata atatcttcat ctatataaaa tttaaagttt cctttaaata agtatacaaa
     5821 atctatctta caatctagct ctctttctaa acgagtaact ttacttaaat tttcatcact
     5881 tatccaattt agtattgagc atatagtgta tttcttttta ggataaatgc tttgaatctt
     5941 cctaattata ttcatgcatg tattggctgt ggtaatctca tcatcaacca atattatctc
     6001 atctccaaat ttaaagttgt taagcatccc aaagtataga ttctggtctg ttgcatggga
     6061 atgttcctct aaaaattcca gattttctaa ctcgtcaaac tgctctctag tagtatgaat
     6121 aaattcataa tctccacata agtaatcaaa aaaactatgc ccaacagctg taccagtttc
     6181 agcaaaagct ataacagtac catttgattc ttccttattt ttttcattat aaattgtagc
     6241 cattaatttt cccaaattat ccatctcact tggcttacat gctaaatgtt taccgagttt
     6301 ctttgagata aacaaaaaac gtcttttgct attatttctt attcctacgt ctaaaaaatc
     6361 atttagttct aaattcaatg gattatcaat aatgtcaatc tcacaattaa aatttaagca
     6421 attcttcata gtctactcct ttatttaata caccatatat tttagataga atcaatgttt
     6481 ttttagccca taaaaaatgt ggatttgttt cattcattct ctctcctaat acacccttgc
     6541 tcacaccata cttactgtct gtactatcca gtatatccaa agcatcagta aaatcttcat
     6601 atgatactgt agatagcgct tgtacaattt gaatttgcat tggatgaatt acggtctttc
     6661 caattaatcc atgatattta tccaataata tttcttctat atacttattt cttatatcct
     6721 tatttgtcat atcaaaaaat tctgatactc caccacttat aggtatatct aactctggtc
     6781 tttgaagata tgtgattata tctaatataa atgaagaaca aatcaaatta ttatatatag
     6841 agaagttttt atctctcctt ataccataca tccctaatat atcagttatg cctactctaa
     6901 tgcttaatat tcttgactta tgtcttaaaa tagcattgta caaattagta aaactaagtt
     6961 cttttttttc attatatata aattcttttg tctctattat tggaataaca tacatatctt
     7021 gaagattcat agaatctaaa gcttctatac aattttcaat taactccgaa tttactttag
     7081 gaattaatat tcctgttata gaatgactat ttttaattat aatctcttta attctcaaca
     7141 gttgctccac atcttttatt cttacaaaaa ttagtggtat tccatcttta ttagttatac
     7201 tttcattgct aatatttttt aaaattaatc taagattttc tatagcctct aactctccat
     7261 ttactccaac agcatcttct aaacaaatag ctaatggtct aactccctta acatccccta
     7321 taatactctt ataaatcata ttatattgag tagctggaac gtataaaaaa gcgcccagtg
     7381 catatttcaa cacatctttt tcagtcttag cactaaagtc ttctggctct ttcaaaaaaa
     7441 ttctctccaa atcatctttg cagatataat cgaaatattt caatgtctag cctcctcata
     7501 tacatagaaa gggccaactt tatacaaatt agcccttaat ataatactac ttattataaa
     7561 ttatagtcgt atttaattct tccaatctct ttgtattatc cttaattaaa gctctattgt
     7621 tttcttctat tctcatagtt tcatctatac cagacttgat agtattgtac attttttcca
     7681 atgtttctat ttgaacagaa cttgttccag ccattctagc tatttgtgca ctttgagtac
     7741 ttacattttg tgcatttcta agcaataatt cattagtttt gtcatcaagt gcttttagag
     7801 attttgcttg taattcttgc tttttaagta atatagcttg agataaacat tgtttaaata
     7861 ctggtaaagt tacgacaaat gcactattta tttttctaat taaaccataa ttattatgtt
     7921 gcatacctct aagcataggt attgtttgga tagctatatt ttctgctatc cttaaatcat
     7981 agactctttg atttaacata tcataaactt ttaatagttc ttgataattg acaacatcca
     8041 tttggtctcc actagtctct gatttttgtt taaagaaagg tagtatttca ttatccattt
     8101 cttctattgc catttctcca gcaacaatat atttttgaag ttcattataa aactcaaagt
     8161 tttcatttaa catagcacct atttgcttat tagaaagtgc tatatctctt tcgtattgct
     8221 caagctcaat ttgaattttc tcaacttctc ctcccaatgt ttcatacttt tgaaacatca
     8281 tttcaatggc attattagct tttttgaaaa gtttttgaac gaaatttggt tccttagttt
     8341 cttgaaaatc gtctaaatca aacttatcca ttattttagt taaatgaacc agcattttag
     8401 aattttcttc atttctattt aattttattg tatttaaaag gctatcagaa actcttgcta
     8461 ctccttcaga tgctttccta ccaaactgta aaatcgtatc tggattttct acttctataa
     8521 gagatgtcaa tgcctcaact tccttagact ttctcagttc atttttttta ttatttgtat
     8581 attccattat atcgaagttt tcttcttgaa ctgctgtagg caaattctca gtaacctcta
     8641 cagagttctt atcttttgaa aaactattta tatttatccc catctaaaat cgtctcctct
     8701 ttccaaaaat ttttttaagt aaaggtatat cattttcaag cgaatttaat ttaaggtcat
     8761 ataccatttt atccaatctg tgtacatcaa tcaattggtt atttataaca ttctctatat
     8821 tgttttctcc tcctggacat aatatgataa tatcaaatcc aatcttacta agtaaaagca
     8881 taagaaaaac tatttcttta tcaaatacaa tactcttgta catgtatata atcaattttg
     8941 ggtttataag tgagtaatcg aaattgttca tcatatgaac aaatttctta tccatgtgaa
     9001 gtactgtaaa tagacctttt atcttgtctt ctccacttaa accattcaaa aacatacttc
     9061 cttctaacaa ctcttccact ttctctaaaa tcataatttg ttgattcaat gctagtgttg
     9121 atatggaata atctttatta tttaaaacag agtttttatc tattgcacct tttgaatcca
     9181 ataaaaagga taaactaaaa gcttctcttg taaaagcttt tgaaaatcta tctacatctc
     9241 cattaaattc aataaatgtt gaactttccg aatctcttaa taaatctaaa aacttaatat
     9301 attcattctt atcgttatat attccattaa tcttagaaag aaaatttgga gcttctacaa
     9361 tagcatcatt aaacttaaat cctggtctta atttaagtgg ttgattccag tatattgata
     9421 tttcatcaac agttgaactt agaagtagat tttttatttt tctatcttgg agttgccaag
     9481 gttttataaa tcctgcatca tttaacaatt cctcacttat acgctttgat gcttctgccc
     9541 caacagtaaa agcttttttt acagaacttt tatctatttt ttcccctaaa ataacccttt
     9601 cttcaaaaga aattttttct tctattatgt tggcttcttc aaactctata ttgtatcttt
     9661 ctgattttaa aatatctata ttactctttg aatttggatt aagatataaa acatcaaaac
     9721 ctgccaagta taatattaag agtaaataaa cttcatgttt ttttatatct ccataaaata
     9781 ttacttttgg agcttcattt ttatttatat ctaaagcacc gatataaatt tttatccatg
     9841 ccattatttt cactataaaa ttttgtttaa ctctatcatt agtaaattct ttttcctctt
     9901 cttttaacac tctatccatt gcttgcttta ttttataatc aatctcttca aatcccaaaa
     9961 tatttatatc tacatcttcc atgctagttc tatatttttg aagtccactt ttaaaataat
    10021 ttataatatc aaaatcacta ggatttgcta taacatcagt aaataaagca atatcttttt
    10081 tgctatcaat attttgtttt gttttaaata tctcgagatt gtacaaaact tcatcttcta
    10141 aaccaatata cgaaataaaa taacttagat atccctttga aggagtgtaa tttcctctat
    10201 ctgattggct ggagaatatt ttttcaaata cctttgagtc acccataact atcctcccaa
    10261 tttaaatgtt tattcagaac tgacccaaaa ttcatatttt gagtcagtct gttttcttct
    10321 aaaaaatttg ttttaagcag tcttttttgg ttttaccagt cttattatac attttacaac
    10381 ttcattaacc acaattacac ttgctgctac acataaaact tttacccatg tcataaaatc
    10441 cattgctaca gagttaaaga aatcttggaa tagctgagta aatattactt gtgcaattcc
    10501 tgtcaacact attatttgta gtgctaattt gttatgtgta aaattaggga agatactatc
    10561 tgcattaaac tctctacagt taaatgcatt aaacagtgca ctaaaagcaa ataacgcaaa
    10621 cattactgtt cccttatgtg cttcatcaac tcctaagaaa ttaaatgtag attgtaacat
    10681 tagtattgct gttatataaa atgcatttaa tactattgta tacaccattg acttagaaat
    10741 tatattggct tttctatcaa caggttttct atttaacaca tggtccctaa ctggctctaa
    10801 acctaatgct agtgctggtg gtccatccat aatgatgttt acccataata attgtattgt
    10861 agtaaatggc atctcttgtc ccataacttg agatattata gccactaaaa atgcaattac
    10921 atttacagtt aattggaatt gaacgaatct ttggaagtta tcataaattc ctctacccca
    10981 tttaatacct tttacaatgg tactaaaact atcatcagtt aaaattatgt ctgctgcgtt
    11041 tttagatacc tctgtaccag atatacccat tgctatacca acatctgctt ttgaaagtgc
    11101 tggagcatca tttataccat cacctgttac tgcaacaaca tctccgctct tttgcagagc
    11161 tgaaactatt ctcattttac tatctggttt acttcttgcc acgattgaaa tactttgtat
    11221 ctcttgtttt aattcttcat catctaaagt atctatatat gaagcttcaa ccactctcat
    11281 attatttttt aataggccta actcttcacc tatagctctt gccgtattta tattatctcc
    11341 tgtaagcatt tttacagaaa caccagcttt atttgctgta tttacagact ctataacatc
    11401 ttttctaagt gggtctctta taccaacaaa accactaaat actaaattgt tttccattgc
    11461 acttacattc atagcatcac tttcagcagt tactgctgct tcttcttcag cttgtgagat
    11521 ttctttatat gcaaacccta aagttctcat tgattttatt tgcaatttct ttatttcttc
    11581 taaaatctca tgttttatat tttcagttaa tggaactatg tcttttcctc tttgaatatg
    11641 tgaacataat tcaagtaaga cttctggtgc tccttttgat aatagtacat gatgattatc
    11701 ttgacctata acagaagtca ttctctttga atctgaagta aaaggatttt gagctactat
    11761 attagaattt tttctaactt gtctataatc tacgtttttg taatataaaa gcaatgcaca
    11821 ttcagtagca cttcctaaat acttaatatc accatcattg tgctctacat cagctgtaga
    11881 gtttatcata cagttttctt caaaataact atttatttcc tcttctgaac tttcaatata
    11941 tctgccatca acatatgcaa cttctacagt cattctattt tcagttaatg taccagtttt
    12001 atctgaacat attacagaaa cagaacctat cgtttcacaa gcttcttttt tagtaaccaa
    12061 tgcatttatt ttagccattt tttgcattgt tattgcaagt gtcatattta tcatagttgg
    12121 aagaccttct ggcactgctg caactatcaa cgcaacacat actgtaaatg ctgttttaac
    12181 tgggtctatt gattctaaaa acggtaatat tccagacata tctacattta atacattctt
    12241 acttatcatt tggaaaacca taaatataaa tagtaatcct gctactgcac tagaaacttt
    12301 ggctatcaaa ccacctaaat ttccaagttt tatctgaagt ggagtttgct catctgtttc
    12361 tgataagttt tgagcaattt tacccatttc actattatct ccaattgaag ttacaactag
    12421 agctcctcta ccataagcta caagtgtacc accaaacacc atatttatct gttttgcagg
    12481 tattggttcc tgtactacta ctgctccttt agattctatc tcttccatag aaactactac
    12541 atcacacttt ttagatacgt catcagattc tcctgttaac atatcttctc taattttaag
    12601 gtttatactt tctataagtc taccatcagc aggtaccatg tcaccagttt caatatatac
    12661 tatatcacct ggtaccaatt cactcttaga aatttgatgt acttccccat ctctcaatac
    12721 ttttacttct atgttttcag tcaacttaga aagagcctct gctgctttct tagaacgacc
    12781 ttctgtaatc atacctattg ctatacctat tgctatagca cctacaatcc ctattgcatc
    12841 atgagtttcc ccaattactg cacttactac tgctgcaata atcaagataa ctatcattgg
    12901 ttcacttaaa ctttccttta aatcatccca aaaactaccc tcttcttttg gagtaaattc
    12961 attcaaacca tatttttctc ttctagtctt gacttctgat tctgataaac ctttttcagg
    13021 attaacagat aagtcttttg taacttcttc tttatctaca ttataatatt tgatatcatt
    13081 attaaattcc atatgcacac tcaatcctgt ctaaattttg cattacttct ttaagacccg
    13141 catcttttgt tccttcacca attgctttaa attgccaact tccatctttt ctatatatag
    13201 ctcctactat aagagtagtt ttttcagaat aattatcaga tagattgtat tttgctatct
    13261 ctttcttatt accttggtct tcaactctta tataggcatt ttctatcatt ccaaagtgtt
    13321 gttttctatc tacacaattg tatatattta ctacaaacaa taatttatga atatttgatg
    13381 gaactttatc caaattaact aggatttgtt catcatcacc tgtaccctca ccagttagat
    13441 tgtctcctgt atgcaaaact gatttacagg cactttttag atttccaaaa taaattaaat
    13501 cttttattcc acttaattta ccttcttgat taagcataaa tacagatgca tcacaatcta
    13561 tatcagcttg tcctccacca aataacgatt taaaaaaacc tccgccagat tgttgcacag
    13621 ggtcccatcc tagacctaca agtatgttac tcagtcctgg gttagatttt tttaaatcta
    13681 ttttatcacc ttttgataaa ttaatcgaca tactaaacct ccacaaaatt ttatataata
    13741 taacctatac attatttgta taggttattt atatttaata tattatattg cttaaattaa
    13801 acatttaagc catagtttct acaaagtgct tctaagccac cttcaaatcc tgctccaact
    13861 gcactaaact tccattctcc attatactta tatatctcac atactgtaat tgcagtttct
    13921 atactaaatt cttcacctaa gtcatatctt aatatttctt catcattttc agaatttaat
    13981 actcttatat atgagttgct tacttgtcca aaattttgtc ttctttcagc agcctcatat
    14041 attgtaactg ttacagctat cttttgtata tgctttggca ttgtctctaa attcactaat
    14101 atttcctcat catctccatc accttcacca gttctattat cacctaagtg ttcaactgct
    14161 ccagatggat gttttaagtt attgtagaat ataaaatctt catctttttc aactctttga
    14221 gattctccaa ccatgaaaac acttacatct aaatcataat catagccact atcaaatgaa
    14281 tttgtatccc atcctagtcc aagttttata tttttaagac ctggatttcc cttagttaaa
    14341 tcgatttttt gtcctttttt taatactata gccatggaaa atatccccct ttagtttatt
    14401 gttatagttg aaattataag tttattccaa agtttccaca taatgcagca agaccacctt
    14461 caaagccaga acctagtgca ttaaacttcc attctccatt gtgcttatat atttcagcta
    14521 ctactatagc tgtttctata ctaaaatctt ctcctaattc atactttatt aactcttcat
    14581 ttgtgtcttt atctactatt cttatataag aattacttac ttgtccaaaa ttttgtcttc
    14641 tttctgttgc atcatgaatt gtaacagtaa aagaaatctt gcttatttct ccaggaatct
    14701 tagataaatc aacaactatt tgttcatcat ctccatcacc ttcgccagtt ctgttatctc
    14761 ctagatgctc aactgctcca gatgtatgtt ttaaattgtt gtaaaataca aaatctccat
    14821 cattagtaac acttccactt gctcctgtta aaaatgctgc tgtatctaaa tcaaagtcaa
    14881 atccaccatc atacttgtta gtatcccatc ctaaacctac taaaatattt ttaagacctg
    14941 gatttccttt agttaaatca accttttggc cttttgataa tgttataccc ataatttatc
    15001 gctcccttgt taattttagc taaacaaatc ttgctaatta tttatctttt tctttaatca
    15061 tattataaca ttttttattc atttgtgaag aaaacttgct tgatattttt aaaatataat
    15121 taaaaaaatg tttatatttc ttacttttta catagatttt acatacttta ttaaatgtat
    15181 aaaagctatg tttaatatgt aattatatat catttatata aacaagtaca tattttattt
    15241 tgaaactaca aaattattgt actatattgt tttaagttgt tttataatag attatatcat
    15301 cttattatag gagaaaaaat atgatttgta ctattaaacc attaaagatt tcaataaaaa
    15361 agtcaactga acctctaatt gaatttatat ctgatactac ctataaaaat aagcgttctt
    15421 catatattaa agaagtctac tttacaagat atataggtgt tgatgattca attgataaat
    15481 acatagaaaa aattaaaaat atagatactt atttttttaa taatcctaca attccctata
    15541 ttagattaaa caatctaaaa ataaattttg acaaagaaca aacagataag atgcttaaaa
    15601 tttttaatat ttataatagt tctaagttta acagttggga tttatataat atcgactttc
    15661 catgtaaaat agaaaatgac accttaaatt ggactaaaaa gattgcattt aaaaatactt
    15721 tagatttatt ttccacaagt atgccaaatt gtacatcctc tatcatcaaa aactttgcag
    15781 ttaaactttt gtgttggatg gactattttc tacctaaatt attttataac aaggtgaaga
    15841 ctactatttc accaaagata gtatactttg gaaatattaa aaggcaagaa ctttttttct
    15901 tatatttttt atcacaactt gggtgtgata ttttatatat aaatccaaat aaagatattc
    15961 ttgatttata tcctgaatgt tcaaaatttt ctactctatt tgaactttct aggaagactc
    16021 caaatatatt agaaatacct tttgaaaggc atattacaaa tataaattac agtgaaaata
    16081 ccaataagac ttctcctact acgaataaac ctaactctaa aaatacactt aataacacaa
    16141 atctaacatc taaaaaaatt gtacaagatg aggaagtaga actttcttat gaagaccttg
    16201 caaagttatc agcttctgtt gttatgattg ttgtgtgcaa taacgaaaat aaaccgttta
    16261 agagcggttc tggagtagta ataaataatg aaggttatat acttacgaat cttcatgtag
    16321 tcaatgatgg gtattcattt ttagttagat ttgaaaatga tgataaagtt tatacatctt
    16381 accaaattat aaaataccat tcagattatg atttagctgt gataaaggtt gatagaaaat
    16441 gcaagccaat acctgttaaa gtcagtaaaa aacctgtgag aggtcaaaaa atagttgcaa
    16501 ttggaagccc tttaggtctt tttaatacag tttcagatgg aattatctca gcttttcgtg
    16561 attttgaaac ggttcaaatg atacaattta cagctccaat ctctagtggt agttcaggag
    16621 gagctctttt agatatgttt ggaaacttac taggattgat ttccgctgga tatgatgatg
    16681 gacaaaactt aaatttagct gttgaaagta atcttgtcaa aatatttgcc aataatttta
    16741 ttgagatagt aaactaatca atcaaaattc tacttatcct attccataat aatcaagagg
    16801 gtgaaaacat tgcatgcttt tgccctctga ttaatattga aaacagtatt aatactcgac
    16861 atttttatgc tcaataaata attgatacca tagacaaaat gtaaatatag tccatatttt
    16921 tctcgaatta tctctatgac ctttaagatg cgtatctaaa agttttattg catatttttt
    16981 atctataaat tcatctacat ttgaattata aatagtttcc tttacaatat cccctagaga
    17041 atcttttaac caaactctta ttggagttgg aaatcctaat tttttccttt gaacaacatg
    17101 ttctgggact atttctctaa aagcctctct aagtaaaact tttgtattat tcttatttat
    17161 tttttgctcc attcttaaat tttttgctac atcaaataca tctttatata aaaatggtac
    17221 tctaagttca acctgctcag ctgtagaaag tttgctaatt ttttgaagta tatcgccttg
    17281 aagccatgta ttcacatcta tatgttgcat tttacttata taatcgtaat tatttttttg
    17341 tgcatctcta tacaaattag acaacaggta ttcatatata ttcttttcct tatacttaaa
    17401 aaagaatctt tttacttcgc tgttttcaaa aacttttgca tttcctatat atcttttttc
    17461 taatggtgtt gtagctctat aaagataatt tcttcctttt atgtttggca taagttctga
    17521 aactcttcct aatatacttt taatataagt aggtgaattg acaactgatt tcatagtact
    17581 atactcttta tatatattat atcctccaaa taattcatct gctccttctc cagacaatgc
    17641 tactttaaca tgtttacctg cctctttaat taagaaataa agacctactt ctgaagggtc
    17701 tgctataggg tcatccaaag aataaattac attcggtaat gattttatat attcatcttg
    17761 tgttatatta atctggatat tttctatacc taacttatca gctgttttct ttgctacttc
    17821 taattcacta tatcctttga cactaaagcc tgcagaaaaa gattttatat ttggattaat
    17881 ttgtgaagcc acagtagtta taatagatga atctattcca ccagacagaa atgttccaat
    17941 ttctttctcc tcttccatat gagttactat tgaatctact actatatttc ttatatcatc
    18001 ctcattcaca tctctattgc ctaagttatt tttagtataa aaaaattttg tactacttct
    18061 aaactcaagt ttattatatc tctttaaaga tagtatacca ttttctaccc taaaatagtg
    18121 acctgctggt atcagcctta ttccttgtat catagtatct tcaggaagta catattgaaa
    18181 tgaaaaataa ctttgtaagc ttctttcatt tatatttaaa tttttcatat attcaagtaa
    18241 aaacttatac tctgaggaaa aaattattgc attttcctta tttatataat aaagtggttt
    18301 tatcccaaat aaatctcttg ctccaaatat actttcattt tctctatcat agattataaa
    18361 attgaacatt cctttaatct tatgtacaca attcttacca aattctatat aagatgccaa
    18421 taagacttca atatcatcat ttgtagtaaa attgtgtcct tttttaatta attcttcttt
    18481 tatttcatga tagttatata tatttccatt aaaaacaata acttttccat ctttttcaaa
    18541 tggtttattt ccataaatag catcaattac attaaatctt tcaaaatcaa aagttttttc
    18601 ctcatcctta tactctattc tactagaaag tcttgtatta tttacagatt cttttatttt
    18661 aaatttaata tcttcttttt tagatatatc acctttataa taaattgaaa tattgccgtc
    18721 catataatca aaattccttt ctgtccttta gtcttattct atatttcata gttttgtctt
    18781 tggctttaaa acttattcaa tttaaaatga aattgctatt aaattcttat aaattatctg
    18841 ttaatatttc atattttttt tatttctaga aatactatat taggaggtga tttttatgaa
    18901 gaaaaaaata ttaataccag ttattatgtc tttatttata atctcacagt gcataacttc
    18961 atttgctttt acacctgaaa ataacaaatt taaggttaaa ccattacctt atgcatatga
    19021 tgcacttgaa ccttatatag ataaagaaac aatgaaactg catcatgata agcattatca
    19081 agcttatgtt gataaattaa atgctgctct tgaaaaatat cctgagcttt ataattattc
    19141 tttatgtgaa ttattgcaaa atttagattc tttacctaaa gatattgcta caactgtaag
    19201 aaataatgca ggtggagctt ataatcataa attctttttt gatataatga cgccagaaaa
    19261 aaccatacct tctgaatctt taaaagaagc tattgataga gactttggtt cttttgaaaa
    19321 atttaagcaa gagttccaaa aatctgcttt agatgtcttt ggttctggtt gggcttggct
    19381 tgtagctact aaagatggca aattatctat tatgactact ccaaatcagg atagccctgt
    19441 aagtaaaaac ctaactccta taataggact tgatgtttgg gagcatgctt actatttaaa
    19501 atatcaaaat agaagaaatg aatacattga caactggttt aatgtagtaa attggaatgg
    19561 tgctttagaa aattacaaaa atttaaaatc tcaagattaa ttaaatatta aaatcctttt
    19621 gaaaaaaact tatgtttgct atataatata ataaaagata gtctaaattt accaatataa
    19681 tgtttatagt gacgattcag gaggattttt atatgataaa agaaacacat gaaaggggag
    19741 gttatatatt cgcacttttg atactcccct ttataaacaa tctgtaccta gttaaatacg
    19801 atattgcata taaaatagta ttaattataa tttatattta ttttgcatat ttaggttctt
    19861 tatttccaga tatagatatg agaggttctt acataagtaa aaaatttatg ttaatataca
    19921 aattatttgg aagtaggttt agacatagag ggtttactca cagtctaatt gccttattac
    19981 ttatttatag tttttttaaa tctctgacaa tcttcactaa caataatata gttttctcat
    20041 gtttgtccag tgggtttata ataggatatc tatctcactt gtgtcttgac cttattacta
    20101 aagaaggtat tgaattgttt tatcccatta ctataaacat ttctttacta cctataaaaa
    20161 ctaactcaaa aacagaaaaa ttcatatcta agctattaaa tttcatagtt atttttttga
    20221 ttggatatca attttatatt ttattatagt tgtagaaaaa ataaataaca atattttgaa
    20281 ctaagtataa ataagtttta tatattttag tttacaaaag aactaaaaat tttgtacttt
    20341 aatacaaaaa ataaaacgta tcttaaaata atttagtact aaatcatttt aagatacgtt
    20401 ttatttcgta caagctaaat cattttatca tctttatcat tgtgatgttt tttatgatgg
    20461 aaatcataat tatgattttc aagattttta tttactctat ttccaatctt ccatgacaaa
    20521 aacaccaata atataaatga tgctatcttt aaaggacttg ttataaaacc ttctatatca
    20581 cttgccacgt aacttataac tataaacatt acaaattttc ctgccaacat tgctggcaca
    20641 aaatctttta aatctttttt accaaaagct gatgcgatag taactaaaca accgggcata
    20701 aatggacagg catacgctat aaataataac ttaaatccct gtttatccat ccaacttatt
    20761 gctttttcag ttttactatt tctcaactta ttaaaaagct tactatcatt aaatctgctt
    20821 attaataaga ataatgaagt tgtcccaagt cctgagccaa tccatgataa caaacatcca
    20881 ataaataatc cttgtattgc agcatttgct gtaactatag caacaagtgg taaggctggt
    20941 ataaagcttt ctataaatgc acttaataag ccgattattg tggctaacac ccaataattt
    21001 tgagtcaaat caagtagttc ttgtatatac tgcatattgc ttttcccctt ttttaacttt
    21061 aactattatt atatactcta tatgtttatt atataccaat ctcaaaaaat gaatctaata
    21121 ttaaaaagta aataatctat ataagtttac agttaaggta taattatttt attatatatt
    21181 ataacaaaaa aggtgatgtt tcaaaataaa aatctgaaac atcacctttt tataacttaa
    21241 attgtcatgt aagttataaa aaatatatat tagacataat attactaaaa atgtctagtc
    21301 agagtaaaat aaattacaca gtacaacaaa tattactatt taattgagtt acttctttat
    21361 aacatttaac cttcttccta ctctgctcaa taattcattc gatatactac atgagttatt
    21421 tgcaacttca gaagcagata attcagataa attatctctt cctattatta ttgccgtatt
    21481 accaacttct acattaggta tatctgtaat atcaacagca agttggtcca tgcaaattcg
    21541 acccactatt gctgctctac aaccatttat tattacgtaa ctttttccac aggataaatt
    21601 tctaggtata ccatcggcat agccaataga taatatagca attacgctat ctctgcttgc
    21661 aataaagact cttccatatc caaaactatc atctttttgt atttttctaa taagaattac
    21721 ttgtgatttt aaggataaaa caggtcgtaa atcaagttgc aatttagtcg tatcatttgg
    21781 agaacttaat atcccgtata atgcaattcc aattcttaca taattacact taagattggg
    21841 ataattaaaa aaaccataac tactttgaat atgtacttta ggaattttta tacctttttt
    21901 taacagaaaa tcaattaact tataaaaaca ttcaatttgt ttatttgtaa agtctacatc
    21961 ttcatctttc agactatctg aaacacacaa gtgtgtaaat atgccacata tatctaagta
    22021 ttttaattta aataccttta aaattgacct cacatcatta acatcaaaac ccagtctgtg
    22081 catacctgta tcaattttaa tgtgtgattt tatgttgtat ttctgtttgt ttaaagagat
    22141 agcatgatta aggtcaataa cactctgtgt aagattgtat ttatgaagtt cctttgccct
    22201 tattgggtta gtatatccaa gaatcaatat ttctcctagt attccatatc gacgtaaatc
    22261 aatcccctca tctattgttg ctactgcaaa tgcttttaca cctatttggt ttgcacaagt
    22321 cgctacttca aaagcactat gaccataggc attagctttt acaactgcca tcaattcaca
    22381 atcttctggc atagcttttt gtatcatctt tacattatgt tccaaattat ttaaatcaat
    22441 ttcaatccaa gctctattgg tatttacctt atgttctcct ttcaagtctt tttttagagg
    22501 tttaagaatc aatataataa ttataaaagc tataaaagat gctatactta ccactatata
    22561 atgaataagg ctattgtcaa ccaagacagt ttgtattccg aatattttag aaaacatacg
    22621 aataacaaca atcatcatag gatgtataat ataaataatt aatgatgatg ttcgcaataa
    22681 cctagctcga gaacctttca aaaatgttaa ggctgtaaat aagaaataca tacatggcaa
    22741 taacataata tacatgctat catgacgctg tacccctagt ttatgtaaaa acattccctc
    22801 acataacata agtaagaatg atataagaaa tccaatcaag ctatttttag ttgacatata
    22861 attagattta ttagatatta ttccaccaag tatgaaaaat acaggtgcaa aaaatatacc
    22921 atttcgtgta taatctgata cttcaaaaat atacccatat aaattcttta atagtggtat
    22981 tttttctaaa aaaccataat aactatcacc aaacatacca attacataaa taacaatagt
    23041 gattactagt gagtacttta aacctagttt ttttacaaga aagtatgcaa tacttgcacc
    23101 aataattgat gcaggtagat accataaatg atataaagtc ccatcaaata caatgtcctt
    23161 aataatattg ggcactaaat tattcatgga aaaatatcca gtgtaaatat ttaagggaat
    23221 ataaattaca atagctatcc cgtaaataaa taatacattt tttagaaaag atttcagttt
    23281 attacaatta taattatatg ttgaaattag aaaaaagcct gatagcataa aaaagaatgg
    23341 cacagcaata cgagcaatta tactagttaa cataaagtca gccattttac tatatgataa
    23401 taatggagat gtatgaattg caattataag taatgcagct ataatcctaa aataatcaag
    23461 ccctgcataa gatttattcc taatcattct tgttcctcca tttcttagtc ctttctattt
    23521 ctccaaaatg tcacaataaa accatcctta ttgttacccg atatttgata tacacattgt
    23581 tcaggtatag agattctcac ttcttcttta gtatgaatag gtacataaaa gatttctata
    23641 attttttctt tatcttctat ttttaaacaa tttgtatacg aaaatctctt aatatattct
    23701 atatattctt caagagcgag attcatttta ttgataatct cagaatgcgg atatcccaca
    23761 taacgaaaat gccatggttc ttgagatatt cctgttattt cttctttttt acactgataa
    23821 cgctctataa aaccataatg tagtgctgcc ttacgaaact cattacaaat accattataa
    23881 ggaaattcag ggcagataaa atctataact tctttcttta accctaaatc aatagcaagc
    23941 cctgtctgat gttcactgtg atttggaagt gctacaaact ttttagtaaa gtcttttcca
    24001 ttgtcacgca gagaacttga atatatatct tgttgttcct ctgcagtacg atatccactt
    24061 acaggtacta tttcatttat tccacatata ctttttaaaa tattttgtaa aatgtttgta
    24121 gcttcacgtt tcataagaat acttggaaac cttgtatcta caggaattaa atctatatct
    24181 tcagatgttt taactggtaa aaaagcattt actagaatta gattcccatc ataaacttta
    24241 tctttagtca ataagatagt atttgtcatt ttatcttctt tatttttatc taataaaata
    24301 ttattcatca ttttatgtac acctcaatta tcttgtccaa tatttcttca aaagacagtc
    24361 caataccttt catcatattt ggataacgac tatgagaagt aaagccagga attgtattga
    24421 cttcattaaa aataatttca ccagatggag ttaaaaacat atctactcta gcaaatccag
    24481 aacatccaag agttctataa ataatttttg ctgtctcttg tattcttttc tcacaatcca
    24541 aatcaattct agctggcata tgaatttttg aacttttcaa tgtatatttt tctgtataat
    24601 caaaaaatcc ttttgacaat tctatttcat ctactcttcc aacaagtaag tcatcgtttc
    24661 ctaaaactgc acaccctacc tcaaaaccat caatattttc ctcaattatt acttcattat
    24721 catgttcaaa agccaagtct actgctactt gtaactcttc ttttttataa attttactaa
    24781 taccaaatga tgaacctgca cgcacaggtt ttataaataa tggataagtt aagtcttttg
    24841 acagttcagc cacattaaat ttatctgagt attttagtaa tattgatttt ggtactttaa
    24901 taccttctga atgaacaagt ttatgtgatt tgtctttgtc catacataat gctgaagaaa
    24961 gagtaccaca tccaataacc tgtatacctg ccaattcaaa taacccctgc actgttccat
    25021 cttctccatt ttttccatgc aatataggaa atacaaaatc aagtttagtg tatttaatat
    25081 cattttcaca tgattcaata gcactatttg gaatatgatt ctgagaaaca gcatcaggaa
    25141 ttaaaaattc aataatacca tttttgacac ggttctgcga aacaataact ggaattatat
    25201 cagtatccct ttcaaaccaa gtgttattct ggatattatt ataatctcca atataatgat
    25261 accaattacc ctcccttgta attccaattg gtataatatc atatttttcc gtattcaaat
    25321 tctcaagtac tgcaaaagct gattgtaatg atacatcata ttctgttgag tttccaccaa
    25381 atataactgc aattttttta ttattcatct ttgattctcc tttgttgatt tatttatttt
    25441 tatacaatct acagaaacat gttaaaatac tttttctatt tcaaatccaa tcaaccttca
    25501 cttacaattg catctgttcc acataatata ttttcacatt tttctattga tataattact
    25561 gtatcaaaat aaaagcactc ttgttttgat acagtaatta tatcaataac aagagtgctc
    25621 tttatttatt tatcctaaag aatttcctat ttttttatac ttaaattctt acaaatttca
    25681 tacaatcgga ataataacct taaaggtaat tatattgttc tcgctatgag ctgttattgt
    25741 cccgttatga agctccacta tttctttagc tatagcaagt cccaacccag ctctaccact
    25801 gtttgaatta cgagatgtat ccaacctgta aaattgttca aaaatacgct caagtttttc
    25861 ctctggaatc gtattgctat gattcataaa tttaagcttt atataatcat cctcctgtac
    25921 agctgttatt tcaatagtag tatcttcaaa actataataa acagcatttc gtaataagtt
    25981 atcaaataca cgttgcattt tattaacatc acaccttatc atcatatttg gtgtaacatt
    26041 cagtgtatat tttaaattct tactcatcaa agtaggttta aactcatatg ttagttgttc
    26101 aagcatacga gttaagctta ctgtactgta ttcaagtgat atatttgata aattaaacct
    26161 tgtaatttca aagaattcat taattaaatc ttcaagacgc tctgccttat ccaacgaaat
    26221 agataaatat ttttttcgca gttcttcaga aatctgactt tcatctcgaa gtagtgtcag
    26281 ataccctata actgatgtaa gtggtgtttt taaatcatgt gcaagataaa caataagttc
    26341 attcttacgt tgttctgcca tttgtgtctc aaatttacgt tgttcaagta tatgtttaat
    26401 tgagtttatt ttcttttcta ttgccaataa ctctggagat aaagccactt ctccaacatc
    26461 ttctttgata agagagtcaa taccttgatt tatttcacta aaatattttg taaaccaatt
    26521 taaataaaca cggaatatta taaaaaacac aatcaccata gctagtatca tgaagagctc
    26581 catactatta cggaaaatct gctgatataa attcaatgca gctttatatt ccatacgaaa
    26641 agcattttca aagaatgata ctatccagat agaaaactta ccatacaata taaaagaata
    26701 taaaatccat atgaaaataa tggctataaa tgccattaaa gctgttctca taaaaatttt
    26761 atttctcact tgagtaaagt caggattgac tttaatattt ttacttttca attgtataac
    26821 ctactcccca tacagttttt ataaatttcg ggtttttaga aggttcatga attttttcac
    26881 gtaatcgccc tatatgagcc ataactgtgt tattattatc aagatatttt tctccccata
    26941 cagcttcaaa caattcttca gaaggaacca cttttccttg atgttcacat aaataccaaa
    27001 gaatagaaaa ttcaatcggt gttaatgcta cttctttccc aaataaacta catttatgtg
    27061 tttctttatt gataatcaat cctttaatat catactcatt aacaattatc gactgttgtt
    27121 cataagaatt attatatcgc atatatcttc ttaattgtgt ctttactctt gcaacaactt
    27181 ccaaagggtt aaatggcttt gttatataat catcagcacc tatggttaaa cccattatct
    27241 tgtctatatc ttcaatttta gctgttaaca taatgatagg ataatagtat ttttctcgaa
    27301 ttttctggca aatatgaaat ccatcaatat caggaagcat aatatctaaa atagccatat
    27361 ccaaattttt agattcaata cattctagag cttccttacc tgtataaaac ttgtatactg
    27421 taaaaccttc attttttaaa tatacttcaa ttaaatctgc tatttctttt tcatcatcca
    27481 caatcaaaat attttcgttc atagattatt tttcactctc cttattatcg aggtcatcat
    27541 ttataatatt ggtaaattta catatcaaat aattacaagc atatttgtaa ctaattttta
    27601 taagaaaaga actactacat cagaatgtgt tgatgctact attggaacac aaaaactgag
    27661 attaattgtt attataaaaa ctcccctaac acgtccttat tatcgcataa caggtattaa
    27721 ctttcaataa aaatatctat cagtcaaaca caattcaatt tattatacca gagacaatcc
    27781 atataaaaaa caattaaacc tatgtatgta accacagaca ttactaaaat ttccatgtta
    27841 ttttatataa aaattcaaaa aaggagttga atttaaaatt tgattagaaa aaaatcaatt
    27901 ttgagacaac tcctttttat tttaatgtat ttaaattata gtatatcagc cttcataata
    27961 tcctcaaaat cacctttttc agatattaat cttatcaatt taacagtaca gcttaaatca
    28021 tttataagta tagctccaac taatgaacca tctttcataa ataatttttt atatattctt
    28081 tgaccttcat cttttgatga aatttcttta tcaaaatttt gtatattacc aatactaaat
    28141 acttttacat tcattgcatc taatgaaact ggatatactt cactttcaaa tgtcaaatta
    28201 tctccacttg catttgcccc tgctattttt cccatttcta ctgaagatgg ccatattgct
    28261 aaactaatat ttcccacttg tgcaacatct ccacaagcat atatatcttt aatatttgtc
    28321 tgtaatgtct tatctacaac aatacctcta tcaattttta cagatgtatc ctgaaccatt
    28381 tgagtgtttg ctcttacacc aattgaaaat actaccatat cacagtcaac actatctcca
    28441 tctttaaata caactttttg agcttttcca tcaccttcaa taccatcaac tgctacaccc
    28501 aatcttacat ctattcctgt atctcttaca cattgttcta atattttact accttcttta
    28561 tcaagttgtt ttgatagtat gctatccatg gcttcaacta ctactacttc taatcctttt
    28621 agtctaaatt cccatgcagc ttcaagtccc aataaaccgc caccaatcac tacaactttc
    28681 ttagattttt ctagtgcttc ttttacacta tataaatctt ttatatttct aagagtaaac
    28741 acattttcta aatcatggcc cttaattggt ggtataaagt ttctacttcc tgtagctatt
    28801 acaagcttat caaatttaat agctccatca ttcactataa tagttttatt cacttcatct
    28861 aatttatcta cattcgttcc taatattact actatattat ttttatcata ccaatcttta
    28921 tcttccatgt agaaatctga accaagttct tcatttatac catcagaaag tgcaggtcta
    28981 tagtaagtca actcatcttc attagaaatc atagttatct tacaagtttt atttcttttt
    29041 cttatagcat ctgctgcata aaaaccagct gctccatttc ctactattac gaaatattca
    29101 tcagtatctt ttctaaaagt aacttcatct tcttcaactt ctataaattg gtcttcctta
    29161 gctccacata cagggcatac actaggagca ctatcacctt caaaaacttc attacaaatt
    29221 acacatttaa atttcttagt tttcttttta cttccaaaag tagaatttaa cttatctagg
    29281 aatttacctg tataagaatg taatttatca atctcttcat ttgatggttt aaagttaaca
    29341 gcaaaaggtt ttactgctgt cattctaagc tgacttattc tctccatagc attttctata
    29401 ccttctccac tccatccata tgaaccaaat actgaagcaa cttttccacc atgaagaact
    29461 gggtttaacg atattaatat atcccatata ggctttaacg catctcctaa tattgttggt
    29521 gttccaaata atacaccttg tgatactgct atttttgcca aaatatcttc ttgcttatgc
    29581 tctattacat caaataaatt tactttatag ttgctatttt tttcaatata tgcttttata
    29641 gcttctgcca taatctttgt atatccatgt gcagaaacat aacaaattgt aacttctttt
    29701 tctaacttta tttgttcatt tacactccag ttgtaataaa ggtctataat ttttctagga
    29761 ttttcagtta atactggacc atgacctgga catacagtat ctatatctaa atcttttatc
    29821 ttttctatag cagttaccat agatggttta aatggaccca ttatacaatc ataatagtat
    29881 cttaaagcat ccaagtaatc cttttcttca ttttcatcaa gtgtatttac tatcttatca
    29941 ttactatagt gactaccaaa tgaatcacat gttacaagag ttttatcctc ttttatatat
    30001 gtgtatatgg tatctggcca atgaagcata ggtacagaga aaaattctaa agttttgtcc
    30061 ccaattgata atgtatctcc atctgtaact gcaacatatt caaagtcttt gtttacgatt
    30121 tccttaagat atttaattgc tgtttctgaa gctactactt ttgcattttt agctaaatcc
    30181 aaaagctttt caacgcttcc tgcatggtct ggttcagtat gacttacaac aatatagtct
    30241 attttttcaa aatctatatt taaatcattt aatctttcaa tataattgtc aaaatgctta
    30301 tctttaactg tctcaaataa aactgttttt tctgttcctt ttaatacata tgaattataa
    30361 gtagttccat aaggtgtata cataattatg tcaaatactc ttaaatcagg gtcaagcgaa
    30421 cctacccaat ataaattttc ttttattttt agtgatttca atgacatacc gtactcctcc
    30481 taaaatagtt atttagtctc tttataccct gcttgttata ttttaaacaa aatttattca
    30541 aaaaagaaat tattttaaag atagtttaaa tcttctaatc ttctttttct accttcaata
    30601 cagttccctt tttagaatct acttttatgt catattcatt tttatcttta tctattctta
    30661 ttttataaaa agtaacatct aaatctttgt ctaaactcca ttctttaact attccatttt
    30721 gttcttttaa tgcaatttcc atagcttgtt gaggtgtcat tatgtcattt aaatctaatt
    30781 tttcttttct agcaactcca tttaaatctt ctgaatccaa cttttctgtt ttatcttcta
    30841 atacatcttt tgtattagca tcaattttca tcttatattc attattatca tctacacctt
    30901 ccacagtata aacaaattta tttaaatctc tctcaagact taaatctact atatcagcat
    30961 ccttatattt atctttaaat atgtttattg catctgtgta tggcacttta aaatcttgtt
    31021 ccattaaatt ttcattattt ttttcatctt ttaaagcgtt atttgatgca tttgcctcct
    31081 tttttgtatt atcttgtgct tgtcctgaat ccgtagttgg actcccacta catgcagtta
    31141 ataaacccgc tataagcata cttaccacta ataaatacgt ttttttacac ataaaaaccc
    31201 tccttaaata tattaattta ttctatatta tgccctctaa accctttatt taccctttta
    31261 tattaaaaat tcctcctatt ttatcaattt taaaacttta tatttactaa aattaaagtt
    31321 acataaaaat tatactgtct caaaatggaa acaagcatct ttttcattgt tgaaataata
    31381 aaaatatatt ttatttcgta caaaaagagt gcctcatgaa ctaaaaagtt cattttgaga
    31441 cactcccatt tttttatatt tttacttaca aaataacagt acttattaat tttttacaaa
    31501 ccttataagt atatctatat gatattctta aatttaaaca ctatattaaa aaattaaatt
    31561 ttgtttaatt cttttaccgt taaatccatt ttaggatatg gaatcgtaat tccttcttcg
    31621 tcaaacctaa ctttaacctc ttctagtaaa tcaagataaa ttgtccaata atcttctgtc
    31681 ttgcaccaaa ctctagttgc aaatttaata gcattatctc catgttctac tactcctata
    31741 aatggttctg gttcatttat tattaattta tgattattaa caatatcttt aagtactctt
    31801 ctaacatgta gtatatcatc ttcataccct acactaaaag tcaaatcaac tcgtctagta
    31861 ttctttgctg aatagtttat tagactatca tttgatacag aaccattagg tataagtatc
    31921 tgtttattat ctggagtaac caattgtgta taaaaaagac ctatttgttc aaccgttcct
    31981 ccatgacctg ctgcttctac gtaatctcct actttaaaag gtctaatcaa tagtataata
    32041 aatcctccag caaaatttga tagactacct tgtaaagcca aacctattgc tacccctgct
    32101 gatgctatca cagcagcaaa actggacaaa ctcattcccc aatattccag aacaatgatt
    32161 ataacggcaa ctttaagtac actcaaaaga agagacttta aaaactttct taaagttaaa
    32221 tcaatatctc ttttactaag taataacata acatggttta caaatttttt tattatttta
    32281 aatccaatag aaagtataag tatgcctatt ataagtttta ctccgcttgt agtagcccat
    32341 tctaatagac tttccattat acctcccata tccatcttat taatatctaa attatttaaa
    32401 tctaacttgc ttatatcatc tattttcgtc gtatccataa aaaactcctt accttatatt
    32461 ttagaaccaa tattatagtt taaagttctt attttctatt taatataata caataccatt
    32521 tgtacatagt aaacaagatt tatattccaa ttatacatat taggaaaatg caaactattt
    32581 gttatatata tgcaaaatat aatactaaat taaactatta ataaaacact atatagcctt
    32641 aaaatcatca ttttttaccc ctatatgaga tgatactata gttataatac ttagtactat
    32701 aaatactaca aaaccttttt tatatccatc aactatatta tatgaattta cttgtaaaga
    32761 gatagctata atcaaattaa taattccact tcctataaat tcaaaagtat taataacact
    32821 agttgccagt ccagaataaa tttctttatt tttatacttg gcatcattaa aaacctgtag
    32881 atgtgacata actatacatc ccataataaa gaatgatatt ggtaaaacta taattggtgg
    32941 ttttacctgg tatccaacta caattacaat ccatataaac aaatctatca ttgctccaaa
    33001 ttttattata ttaaatttgc tagaccttat tttagcaaat acaaaatcca taattattga
    33061 accaaatata aatccatatg taaaaaatga tactataaac gcagaaaaac tcttactcac
    33121 accataaacg tccattatgt atcttactcc ccacaagctt ataaatgcac ttgtaagacc
    33181 cacaaaagag aacattatca ttgaattata ccatgttgat ttgttcttta taacagactt
    33241 aataccatca acaatattaa ccttctctga attttcatag ggttcagtat ctacattgaa
    33301 tccatactct tttggtgtat ctctaacaat aatatacata aaacatccaa ttacaacacc
    33361 aattataccg attaataaaa atgaatttct ccaaccaaca agttcagaca aaaacacaag
    33421 tggaaaagta gcaagaactc cacctaaatt tcctacaaat gaaaatttag ctgttgcaga
    33481 agcaaattct gacttattaa accatctccc ttgaattttt aaaatacaaa gtaatattac
    33541 tgatgttcct gcccctacaa ttacacgaga aatatatgct aattctatac tttgaatcaa
    33601 accaaataaa attgacccta aacttgccat tattattcca agactgctaa tttttcttgc
    33661 tccatattta tcaatcaaaa ttcctgcagg tatttgcata aatgcatatg catataggca
    33721 aaaggatgct atatttgaaa tttgtataga attaaaacct aactcatttg ctaaattgtc
    33781 tgaaacaaca gcagttgaca tccttaaaaa taatactaaa acaaatgaaa atgtaattat
    33841 accccaaaca ctccacttag cctttgtata acttttcata tcttctccct caaatccata
    33901 tatttttaaa ttttcttgat ataacttata taaagtgtat agttattctt acaaattttt
    33961 acacgcaata tcattataca acatatgtat atatttaact agaaataaaa cactattcat
    34021 attatataca tgaattaact acataaataa taagagccat cttttaacat tactcaaaag
    34081 atagctccat ataaaaacat ttattctaaa tttaattttt tatctaatat aaattttgta
    34141 gcgaaaaata acgctattgc aactacaaga ctaccaagta ttgcaagcat aaaactagga
    34201 ctctgataaa gatgatatac catatttgta tcttcatttg gtaagatgct tccaactgca
    34261 tctccaacaa ttgatattac tatatttata gctataaaag aagcaaatgc cactatgttt
    34321 ctatgtttat tgaattttgg caattgtccc attgagattg atgtatataa taacaaaata
    34381 aatgatgaat atgaaataaa cattactact actaataata aaatatctaa aaagttttca
    34441 gaaatccatt taaaactagt gttaaacaaa tctaaaattt caggtagtaa aattccagaa
    34501 gtaccaaaaa gcataagaac tccaaaagtg aatactgcaa ctataaaact aagtacagcg
    34561 tatataagtg ctgttataca tttagataat ataagtgaac tagtgctaac aggaagagta
    34621 aacattaaat aaccttcatc ccccaaaaga ttttttctaa acctttgaat tgtaactaca
    34681 atagttaaaa ctcctaatgc cataaaaaga cttgttaata ctagtattcc tattccctgt
    34741 acctgaagta tatttgtatt cataaatatt ccattaaata cagctactat caatatggct
    34801 atatataacg gtataaatat tcttccactt gcttttaact catattttaa taatttacct
    34861 aacatttaaa ttcctcccta aataatgcat ctatagattt tcctttttct tctcttattg
    34921 cttcaacgtc tccttgtaac actatttctc cttttgatat gaatattatc tcatcacata
    34981 tgttttctat ttcacttatt aagtgggtag caatcagtaa agtactatct tcagaataat
    35041 tttttaatat agtcttaagt atatatgacc ttgcagctgg gtcaacacca cctataggtt
    35101 catccaatat atatatgctc gcatttcttg acattactaa aataagttga actttttctt
    35161 tagttccttt agacattgtc tttagctttt catttacatc aatatctaag cttttaatca
    35221 tctcatttgc tcttctaaca tcaaaatcac tataaaaatc atagaaaaac ttaagtaaat
    35281 ctgatacctt catccaatca tttaaataag ttctttctgg taaatatgaa actatttttt
    35341 tagtatctat ggatggtttc attccattta tcataatttc accattatca ggctgtaata
    35401 atccattcat tagcttaatc attgtacttt tgccacttcc attaggtcct aacagcccga
    35461 ctatttttcc ctttggtata tttaaatcaa tattttttaa aacattctta gttccataac
    35521 tcttgtttac acctttaaat tcaactattc catcttgaga aacattgctt atatttttat
    35581 ccattttata attctccttt cagattttct gtaataagtt ttagcatttc atctctatca
    35641 tatccaagct tttctaaggt tacttttaat gtatttatct ccacattagc tatttcctct
    35701 ttcatagctt ttattttttc cttatcatct gttacaaatc ttcctttagt tctctgacta
    35761 taaactaaac cttgtctttc aagttctgtt agagcctttt gcattgtatt tggattaact
    35821 tccgcatctt ctgctagtgc tctcactgtt tctaatttag atcctatttt aatttcccct
    35881 gaaattattt ttaactttaa atgttctact aattgtatat atataggttt gttattatca
    35941 agttcccatt ccatgttcat gcctccttat tatattattg tattaagttg ttaatacaat
    36001 aatataataa tacaaagtat atgtcaatta ctttttagta aaagtataaa aaattttaca
    36061 aaaaaaatga acactacatt agagtccatt tttaacacaa tttattaaat tctttatatt
    36121 acagattaat taccctctta ccaagttaga tacaattaaa tgttcaaatt cttcaattgg
    36181 cattggcttt ccaaacaaat atccttgtgc catatcacac tttacttctt ttaaaagttt
    36241 aaactgttct tctgtctcaa ctccttctga tatgactttc atacccaact cttttgccat
    36301 ttctattact ttagtaacaa ttattttgct tcttttacta ttataagttt ccataataaa
    36361 tttttggtca agttttaaga tatccatagg aatttctttt aacatattta atgatgagta
    36421 ccctgaacca aaatcatcca tagatattaa aaatcctatt ttttttaaat tattcattat
    36481 atcaattaaa atatcaaaat tatcaaatat gatactctcc gttaattcaa gttctatata
    36541 ctttgcaggt atattgtatt tatcaattat atttttgtat gtttctataa aattattgca
    36601 atataaatgt atccttgaaa cattaactga aacagtaact ggatttattc ctgcatcaat
    36661 ccattttcta aggtatatgc atacttcttc aagcacatat aaatctaaat ttataacaaa
    36721 accgtttctt tcaaaaaatg ggataaattc atttggaggt attagccctt tatcaggacg
    36781 tttccaccta acaagtgctt ctgaaccttg tatctctcct gtattaagtt ctatcttagg
    36841 ttgtaagtat ataataaatt ctttattttc tagacttgaa aacattgtat tttccatctc
    36901 tttttctttt atctcttggt catgaatctt attatcataa aatgcatatg aacttttatg
    36961 tcctcccttt gccattttat gaggtatatt agccctatct atgattgagt tgatatctct
    37021 atcttctgga agtataaaat agattccaca acttaaaact aacttatatt tttcttcttg
    37081 attattatta aacaagtcta attcttcaaa tatagttttt aacctctttg ttatatcttc
    37141 ttcttctata tatttcataa ttataataaa attatccgca gatattcttg caaacatttc
    37201 ctcttcaaat atattactct taataatctt tgttaaatta cgcaaaattt cattcccaac
    37261 ttcatatcca aataaatcat ttatatattt aaatttatca atatctatat ataataaagc
    37321 atactttact tgagtatttt tacatagtat tttgttagca tcaattacaa atttatctat
    37381 agtatttgct cctgtaagat tatctgtata tgctatcctt tgcaatttaa ttttaaaatt
    37441 taatttatca tatattatat agaatataag tattacacat attatagcca taataagtat
    37501 tatttgtatt gcatgtttgc taataagctg attattagac acaatagact caaagttatt
    37561 tatggagttg tttttataga gtttgcataa agaatagact ggtgttgtgt atgtaatttg
    37621 taaaattata caaataaata aaaaaaacat caattttttt tgtaaattcc tcataaaaat
    37681 ttcctcccat taaaacacct ctattttatt agcaaataag tacatctcaa aagtttccat
    37741 ttcttgtaaa atggatagtt tatatctact ttaattttgt aaaattttct gctactataa
    37801 ttatagaatg tagcatattc attgtcttaa ctattgattt atatatttca tataggtata
    37861 ataga
//
LOCUS       DAEQAF010000033        37174 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.034, whole genome shotgun sequence.
ACCESSION   DAEQAF010000033 DAEQAF010000000
VERSION     DAEQAF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37174
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.034"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..285
                     /locus_tag="KRN00_001716"
     CDS             <1..285
                     /locus_tag="KRN00_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1827582.1"
                     /translation="NRKLSRSISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQIC
                     NKCGYKNEEVKDLNIREWIYPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            717..971
                     /locus_tag="KRN00_001717"
     CDS             717..971
                     /locus_tag="KRN00_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827583.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            1007..1330
                     /locus_tag="KRN00_001718"
     CDS             1007..1330
                     /locus_tag="KRN00_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827584.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLFQIDWGTGNNLIKRVKKIL
                     IDYII"
     gene            1604..1756
                     /locus_tag="KRN00_001719"
     CDS             1604..1756
                     /locus_tag="KRN00_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827585.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            1950..2834
                     /locus_tag="KRN00_001720"
     CDS             1950..2834
                     /locus_tag="KRN00_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBH1827586.1"
                     /translation="MVGAFVLPNYAIILSEMSNLWGNFIMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMGLVSVLFFTYSIYLCATWEDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VGKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAIT"
     repeat_region   3140..3564
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=3140..3168
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            3755..3907
                     /locus_tag="KRN00_001721"
     CDS             3755..3907
                     /locus_tag="KRN00_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827587.1"
                     /translation="MKNRRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            4027..4392
                     /locus_tag="KRN00_001722"
     CDS             4027..4392
                     /locus_tag="KRN00_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HBH1827588.1"
                     /translation="MKNELMMFEGKEIEVFEFEGRILFNSKDVANCLDIKNVNENIRL
                     MNEKQVVKLRNSDISNTDIRKLNNAGENFLTESGVYKLIFKSRKEEAERFQGWISDEV
                     LPSIRQTGAYINNNAIPKS"
     gene            4389..4841
                     /locus_tag="KRN00_001723"
     CDS             4389..4841
                     /locus_tag="KRN00_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827589.1"
                     /translation="MREKASEIEKLQLVYNSTSMLKELLDDAGFDNKSKLLTAKTLYK
                     KAGIDLPIEINEEEHYFDTKQIASKLKIYSKSNKPAQMAVCEIIKKIDLEDGEVKGVW
                     ETNGSWTGTVNKYTKSVIDKVRTWIEENNRPTKIAGEKKNYHVFYKIE"
     gene            4893..5054
                     /locus_tag="KRN00_001724"
     CDS             4893..5054
                     /locus_tag="KRN00_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827590.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(5383..5847)
                     /locus_tag="KRN00_001725"
     CDS             complement(5383..5847)
                     /locus_tag="KRN00_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827591.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKKKILRERKYKKRR"
     gene            complement(5983..6300)
                     /locus_tag="KRN00_001726"
     CDS             complement(5983..6300)
                     /locus_tag="KRN00_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827592.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(6583..6879)
                     /locus_tag="KRN00_001727"
     CDS             complement(6583..6879)
                     /locus_tag="KRN00_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827593.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITNEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKSYLNRF"
     gene            complement(6898..7311)
                     /locus_tag="KRN00_001728"
     CDS             complement(6898..7311)
                     /locus_tag="KRN00_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827594.1"
                     /translation="MKVKSKRSFIVGIIVCMLCCASLVIYCILKDKRFLISSFLLIVI
                     TIFNFCNAFSRKGIVEELHDSADERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(7295..7528)
                     /locus_tag="KRN00_001729"
     CDS             complement(7295..7528)
                     /locus_tag="KRN00_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827595.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            7747..8121
                     /locus_tag="KRN00_001730"
     CDS             7747..8121
                     /locus_tag="KRN00_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1827596.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEEYFKNLK"
     gene            8733..9425
                     /locus_tag="KRN00_001731"
     CDS             8733..9425
                     /locus_tag="KRN00_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827597.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            9621..11681
                     /locus_tag="KRN00_001732"
     CDS             9621..11681
                     /locus_tag="KRN00_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1827598.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(11887..12210)
                     /locus_tag="KRN00_001733"
     CDS             complement(11887..12210)
                     /locus_tag="KRN00_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBH1827599.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(12203..12904)
                     /locus_tag="KRN00_001734"
     CDS             complement(12203..12904)
                     /locus_tag="KRN00_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBH1827600.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(13182..14567)
                     /locus_tag="KRN00_001735"
     CDS             complement(13182..14567)
                     /locus_tag="KRN00_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1827601.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(14675..14818)
                     /locus_tag="KRN00_001736"
     CDS             complement(14675..14818)
                     /locus_tag="KRN00_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827602.1"
                     /translation="MYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKEGIKIIGRF
                     EIN"
     gene            complement(15012..15434)
                     /locus_tag="KRN00_001737"
     CDS             complement(15012..15434)
                     /locus_tag="KRN00_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBH1827603.1"
                     /translation="MNAFKTEVLLKYSAKDIFNIFIKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALVRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            15912..18815
                     /locus_tag="KRN00_001738"
     CDS             15912..18815
                     /locus_tag="KRN00_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827604.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSIKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNIKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPVKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSILHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            18848..19294
                     /locus_tag="KRN00_001739"
     CDS             18848..19294
                     /locus_tag="KRN00_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1827605.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGDMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            19417..19719
                     /locus_tag="KRN00_001740"
     CDS             19417..19719
                     /locus_tag="KRN00_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1827606.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            19900..21306
                     /locus_tag="KRN00_001741"
     CDS             19900..21306
                     /locus_tag="KRN00_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1827607.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            21650..22708
                     /locus_tag="KRN00_001742"
     CDS             21650..22708
                     /locus_tag="KRN00_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1827608.1"
                     /translation="MGNKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCGKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            22807..23493
                     /gene="araD"
                     /locus_tag="KRN00_001743"
     CDS             22807..23493
                     /gene="araD"
                     /locus_tag="KRN00_001743"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBH1827609.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            23511..24158
                     /locus_tag="KRN00_001744"
     CDS             23511..24158
                     /locus_tag="KRN00_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBH1827610.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPIIPIVYESVNYGGYVDIASYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(24331..25698)
                     /locus_tag="KRN00_001745"
     CDS             complement(24331..25698)
                     /locus_tag="KRN00_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBH1827611.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(25888..25976)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            26404..28524
                     /locus_tag="KRN00_001746"
     CDS             26404..28524
                     /locus_tag="KRN00_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBH1827612.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKYLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNVLEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            28628..29881
                     /locus_tag="KRN00_001747"
     CDS             28628..29881
                     /locus_tag="KRN00_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBH1827613.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDNTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENYLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(30035..31096)
                     /gene="ytvI"
                     /locus_tag="KRN00_001748"
     CDS             complement(30035..31096)
                     /gene="ytvI"
                     /locus_tag="KRN00_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1827614.1"
                     /translation="MDIQKQKNFIIKFTYVVLITSIVYIVLKFLLPLLMPFVISFIIA
                     SILRPIIRLITNNTNLNRTLISIVILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEI
                     YKSSIQPTLNTLFSKIDASTPNVNLALILGWDNISQSMMSLVASISTNALNAIASIAS
                     KTPAFMLKLIITLIASFFFTFDYQKIVNFILKQFPEKSQFMIINIKNSSINALLKLLK
                     AYAILLSVTFIELLIGLTILKVENAFTISVIIALVDILPVLGTGSILTPWMIISLING
                     NINLAIGLLILYIIITVVRQILEPKVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFP
                     IAATIIKNLHDNGIITAFK"
     gene            31370..32110
                     /locus_tag="KRN00_001749"
     CDS             31370..32110
                     /locus_tag="KRN00_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBH1827615.1"
                     /translation="MKNFRDLGGNKTEDGRTVKKGLFYRSAKLSNLSENDIKILKELN
                     IKYIFDYRSDEEARKHPSTIISNIKNIRIPAMRELEESGGSFGSIEDMIDGLFEKDGA
                     FNMLNNSYYNLPINNPSYKKLVELIRDYSNLPILNHCTAGKDRTGVGSAIILMILGVS
                     RENIMKDYLKSNDFADKEIERFIEYKPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEE
                     YISVEAYLYGEFNLNKEEIRKLRNQYLE"
     gene            32122..33900
                     /locus_tag="KRN00_001750"
     CDS             32122..33900
                     /locus_tag="KRN00_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1827616.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQFRNGKILSIRGVGYKLEGSFDEVNINSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRMLEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKA
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            34067..34984
                     /gene="pfkB"
                     /locus_tag="KRN00_001751"
     CDS             34067..34984
                     /gene="pfkB"
                     /locus_tag="KRN00_001751"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBH1827617.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSC
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKQF"
     gene            35021..36940
                     /locus_tag="KRN00_001752"
     CDS             35021..36940
                     /locus_tag="KRN00_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1827618.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVTEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVAAINNAMVGFLNGLGGTSKIVLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYIMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMFLALLKKPLNQEV"
BASE COUNT        14823 a         4025 c         6125 g        12201 t
ORIGIN      
        1 aatcgtaaac tatctcgctc aatttctgat gtgtcatggt cagagtttat tcgtcaatta
       61 gaatacaagg ctaattggca tggtagacaa attgtaaagg tgggtaaatt ctttgcaagt
      121 tcacaaatat gcaataaatg tgggtataaa aacgaggaag tgaaggactt aaatataaga
      181 gaatggattt atcctagttg taatgaaact cacgatagag atataaatgc aagtataaat
      241 atattaaaag aaggattaag actaataaca attcaaaata aataacgtat gtaagaaccg
      301 taggaactac ggggatagcc tgtggagaat tagtaagaca tatgttagta tgcaaaattc
      361 tgtgaagcag gaaacctgtg actttagtca tgggaggttc aggctagtat tactcattat
      421 tgtattcaaa agctaaagtg gaaacctagt gaatatatga atttagaagt taatgagaga
      481 gcattagcag ccgactcaat acttattaaa attgaagatg aagaagaaac aatgaaagaa
      541 gctgaaagag agaaaaagag aggtagaaga aggtagaatt taaagttaaa atagttacat
      601 tgctaatata tgaaaatgtt acaaatttgg aaatagatgg atatatatgt tgtatagtat
      661 aatgtagata atatatcacc aagtaaaaaa caacaaataa atctaaatta tgaggggtgg
      721 aaaataaaga tattaaactt acaatatgta tatttgcttt tgtaattgga ataatagtgt
      781 tattttgctg tataggtcta ggtcaattta atatggattg tattataaaa caaaatggtg
      841 ggtcaatagc taccgaacaa tacaacatat atttagaaca atctatttca caatatagaa
      901 attttggttc tatactggtt ttactaggag gaataggaat actgtttgat aaaagtgtca
      961 gaaaatacta aaaaagtata tttttattta ggatgtgatg aatgatatgg caagagatgt
     1021 atttagtgta aagatgacac cactagaagc acagaaaatg gtagaaaaaa atttggaagc
     1081 agatttagtt tctgttgata tttataacct agaaaataat aagtctataa tagttacaat
     1141 ctttgaaaaa tattatgcaa gaagcaatag tgatgcaggt ttggtagtga tttgtgaaaa
     1201 tactacagga aaaacacttg ttaaaattac ctcaactggt agtgcaattg gactatttca
     1261 gattgattgg ggaacaggta ataatttgat taaaagagta aaaaaaatac ttattgatta
     1321 tattatttaa ttattttatg tagatattct taggttggta tggaatttgt actaacctat
     1381 taagtaatca ataaaactaa ataaacatag aaagcactta caaatatgta ggtgcttttt
     1441 attgaaaaaa tagaaaataa aataaaaagt aagatatagg aaaaatatgt aagaattata
     1501 tgttataata attgtagcaa gaagatgtaa tctacaattt atagagtgga gttcatgtat
     1561 taaaaaatta tcctcccaac gataagaagg gaggtgaata tacatggata attttttatt
     1621 taatgtgtta gctagtgtaa cagctagtta catagtttat ttgattagca agttaatcaa
     1681 aaaagtaaaa agccactcta ccgcaaagag tgacttaaag attgatataa attttaaata
     1741 tcatcgtaaa aaataacttt cagttataga acttcactct accgcaaata gattgtagtt
     1801 cttcttgttt ttattatacc acaaattaga aaaaatattg catataatat tttttatagt
     1861 caataaaaat atgaaatttt ttatacacaa tgatgatgaa tctaactaga tgaataaatt
     1921 taattgtaaa taagaaagta cttacttaaa tggtaggtgc ttttgttttg ccaaattatg
     1981 ctataatatt gagtgagatg agtaatttgt gggggaattt tataatgtgg atattagtac
     2041 caataataac aatagtatta cttataatag ctgtttcttc tatgcaatat attttagtta
     2101 tgatagcttt tttgttgatt atatattctt ttatagaaaa gaaaatagtt atgggtcttg
     2161 tgtcagttct ttttttcact tattcaattt atctttgtgc aacttgggaa gataaatcct
     2221 tgatagcaga taataaagtt gagactgtta aggcacaaag agaaactgta gaaagagaaa
     2281 aagaaatgga aagaagaaga atacaagaag aagtagacaa agaaagatat attgaaaaac
     2341 atggaatgga aatatcagaa aatgatttaa aagttaagct agaggcttta gtacctcaag
     2401 aatataaggg gaagaaatat gaattaaaag taggaaaatt taaaagatat agtatgtatt
     2461 ttgatttaac tgtacaaaat gaaaaattta gtaattctga agaatgtaaa aaatttgtaa
     2521 aagaaattgc taatgatctt aaaaaaatta aaataagcaa ggcgtacttt aagtttcatt
     2581 caaaagatga cggcggtata tataattctg tttatattga ttattttaga aacatacaaa
     2641 ataatgtaga taatgttgaa aatttagaat tcaatgagtt tgaacttaaa accgaagaag
     2701 aagagaagcg agaacaagag aaaatagaac aagaaaaaaa cagttataat aactacattc
     2761 aaaacagagt ggttgaccca ctagatagaa taaagaaact aaaagagttg ctagattcag
     2821 gagcaattac ataggaagaa tataataaaa agaaaaaaga attattagaa tagataatat
     2881 agtaagcact tacaggtatg taggtgcttt taaatttaca aagtattcca ttttaatttt
     2941 atagtttaga ttttatgata taataaaaat atagaagttt tgcagtgtgc gatatttgtt
     3001 acaaagtagg gcttaatact tgaaatctaa gatgttgagg gtgcgtgata agtgttatca
     3061 attgcactat tgcccgctca ctgcaatttt aagagtattg tatatatgta ggtattggaa
     3121 atgctaagtt tattttgggg ttttagatta actatatgga atgtaaataa agaaggtgga
     3181 gaacaatatg catgggtaaa gtggcgtttt agattaacta tatggaatgt aaatgcgctt
     3241 aactttctct ttcacttcta ttcctccatt tgttttagat taactatatg gaatgtaaat
     3301 agaatagaat ctaacatata tacacctcca attaagggtt ttagattaac tatatggaat
     3361 gtaaatcact aggacaggca ctccacttct aaagcttata cttgttttag attaactata
     3421 tggaatgtaa atctcgaatc aggatataac tatttaaaag aaaacataga gttttagatt
     3481 aactatatgg aatgtaaatt gctgtgattt cactaataaa acaattaata attgtgtttt
     3541 agattaacta tgtggattca aaattaaata aacaaagaaa gcacttacaa atatgtaggt
     3601 gcttttattc tgctcaaaat tggtcggttg ggtaaaataa ttagaaaaag ttagtaaaaa
     3661 cctattgact gtaactcgtt acaatattgt tattaatgta acgagttaca gaaaagaggt
     3721 gaataaaata gcaactaaaa gtagggcaga gtatatgaaa aatcgtcgaa aagataaaag
     3781 aggttttagt gtacttttag acaaagaaaa gttagataaa tttgatgaag tattagagga
     3841 aaagaatcta accaagaaag aatggctaga agaaaaaatc gacgaggaac tggaacaaaa
     3901 ggaataaaaa ataagggtca ctcccaccga ccaaagtttg agtaacccct atgacgtata
     3961 ctatcgtata tcaattatag tatatgtcat tccttaaaaa aatcaattat taaggagtgt
     4021 aatattatga aaaatgaatt aatgatgttt gaaggaaaag agattgaagt atttgaattt
     4081 gaaggaagaa ttttattcaa ctcaaaagat gtagcaaact gtttagacat aaaaaatgtt
     4141 aatgagaata taagacttat gaatgaaaag caagttgtaa agttaagaaa ttcggatatc
     4201 agtaatactg acatccgaaa acttaataat gctggagaaa attttcttac tgaaagtgga
     4261 gtgtataaat taatctttaa atcaagaaaa gaagaagctg agagattcca aggctggata
     4321 agtgatgaag ttttaccaag cataagacaa actggtgcat acataaataa taatgcaata
     4381 ccgaaaagtt gagagaaaaa gcaagtgaga ttgaaaaatt acagttggtt tataacagta
     4441 catctatgtt aaaagaattg ctagatgatg caggctttga caataaatca aaactattaa
     4501 cagctaaaac attatataag aaagcaggaa ttgatttacc aatagagata aacgaagaag
     4561 aacattattt tgatacaaaa caaatagcat ctaaactgaa aatatattct aagagtaata
     4621 aaccagctca gatggctgtt tgtgagatta ttaaaaagat tgatttagaa gatggtgaag
     4681 ttaaaggtgt ttgggaaact aatggttctt ggactggtac tgtaaataaa tatacaaaga
     4741 gtgtaataga taaggtgaga acttggatag aggaaaataa tagacctacc aagattgcag
     4801 gtgagaagaa gaattatcat gtattttaca aaattgagta aatttatcag ttgtattaaa
     4861 taatttagtt tagttttgag gggattaata caatgtgtga gaatttactt gataatatgt
     4921 atattgaaaa gagaaaagaa gaatatagaa ttaaactttt gaaaataaga gaaacagata
     4981 tagatatata taataagtta gaaagtatag tatataaact ttctgagaaa aaattagaga
     5041 aaaataataa atagacatat aaagcacttg gatattctac tgtttcaagt gctttgtttg
     5101 gtataaaatg gtataatgga gatagagaat tatattaacc caaaaatgga gaaaatagag
     5161 aagatgattt agttgacgct ttatcagtag gagtacttgc aggtaagaca gaatctctag
     5221 tactattagt tggaaatgga ataagtgata ctcaaaaaag tttaataaat aaaagagaat
     5281 ttagaaatat aactcaaatt ggtggaaatg gaaatgagaa agcatttagt gaagtagaaa
     5341 acttagttaa atagattaga aggtagcaac tagagttggt tgttaccttc tttttttata
     5401 ctttctctct ctaagtattt tctttttcat atcttctaat acatctaatg cagtagtata
     5461 aaattgtata ttatttctat aaggtatagc tattggaaga atgcccttgt taactaaaaa
     5521 aataagaagt acaataaata aaagtgtcat aatcattcta ataaaataat tagtgatatc
     5581 tgataaatca aatgttaagt taattgttgt agaaaataca acagccataa tagatatata
     5641 caaagcaaaa atggggttac tatttttttg taactgtcct ttaagcctag attgctctat
     5701 ttctatatct tgaatacttt ttatggaatc catttcacta taatacttat aaacttttaa
     5761 ataatatttt ttatacttgt ttaaagcttc ttcattatct ttaaggtctt tgtcacttaa
     5821 ctctgattta acttccccaa aatccataaa atccctccta caatgttata taatatactt
     5881 taatttatag catatttaag aacttatatc agcaatttgt cgaacgattt tagctaaaaa
     5941 tagagtataa tgataggctt attatttata agatattatt ttttatatag ttatatattt
     6001 ctttctaatt agataatata atgctgttgt tataatggct actaatatta ttgctattat
     6061 tgtaatatct aatcttcttg taaataagcc tattgctata tactcaagac ctgttacata
     6121 gcgataaagt acttctagtt taacagtttt tttcttatct atatttccat atattgattc
     6181 taatttatta aaatattttt tactacaaaa agcagtttta ggtttaatta aatatattat
     6241 tgtagttcct attataacta ttattccaat aagtataaga ttgatatttc caaaatccat
     6301 agcagatacc tcctattaaa tttgcttttc ttaatcaaag tatatcagta acacaagtac
     6361 aaagagcatc taaaatatta caaatattaa caggatagat aaaactatag taaaaattgt
     6421 aataataaag cgaacgaaaa ttatcatact aaaacataag acatgttata attgtattag
     6481 atagaagatt aacatacacc aaagcactcc ttacaataaa gagtgcttat ttttttgaaa
     6541 ttcatcaata tataaactat caagaacctt attcaacaca ccttaaaatc gatttaaata
     6601 gctctttttg ataacataat ttatatgata taataaaaaa atagaagtgt accaccaata
     6661 cacttctata gctataacta agcattctct tgctggggga gtgctttttt catttctcca
     6721 aacaacatta tttacttcat tagtaattat caaatcaatc tcattatctt tcaaaatctc
     6781 tgttgcagta caaattagat tatctaagtc aaaacttcga gttatctcta gttgtttgtt
     6841 atttacttct ctttttagta tataagtttt aaaatacatt tatatcaccc cttgtattta
     6901 ctcttttttc tctaaaaata tattgataag taaatatgca acaaataaaa aaatctcaat
     6961 gacacatagt gttatagcta taactagaag tgattgattt ttccatgcac tataagctat
     7021 gatgaaaaga aatgtaaaag taaataatgt ataattcata attttaacta agatatgact
     7081 tgttttcatt gttaagtaca agtctctttc atctgcacta tcgtgtaatt cttcaacaat
     7141 gccttttctt gaaaaagcat tacaaaaatt aaagattgtt attacaatta aaagaaatga
     7201 tgaaattagg aatcttttat cttttaaaat gcaataaata actaaactag cacaacataa
     7261 catacaaact ataataccca ctataaaact tcgtttactc tttactttca tgttttttat
     7321 cctccatttc tttattttct tttaaacaac atagttcttc aatcgttgta ccaaacactt
     7381 gtgccatacg ataggcaagc ataagagaag ggctatattg ctctttttca atagaaataa
     7441 ttgttctgtt tgatacatgg actaaatcag cgagttgttg ctgtgttaga cccatatttg
     7501 ttcgaaattc tcgtactttt gttttcattc cataacctct ttctatatga agctaacttc
     7561 atgtgaagtt agcttcataa tatcctaaaa tgagtaaaat gtcaatctca ttagataagt
     7621 attataaaac ctaaaagaat aatatggtaa aaattggatg gaattattta ccttaattct
     7681 cttgtttgta aaactttatt gatatagaat ttaacatata cataaatcgg caaaggggcg
     7741 cgaattatga aaattagtaa attaccagaa gcggaattaa aagttatgag atatatttgt
     7801 gaagctaaca aggtattaac ttctagggaa ttagttgctg caatggaaga aaaatatgag
     7861 tggaatgaat caactacatt tacagttttg aaaaggttag agcgaaggga gtttttaagt
     7921 acagagaaaa taggcaaact tacacattat aatatactag taaaagagaa aaaatatcta
     7981 aggtttgaaa caaaggaatt tttgaagaac atacataaaa attcaatttc aagtttaatg
     8041 tcagcgttac atggtgaaga cgacgaagtg gatgaagata aattaagtga actcgaagaa
     8101 tattttaaga atttgaaata agaaaatgac aaattgatac ataataaata aaatgaaggt
     8161 atgaaattat aactttttct accttcattt tgtttattat tctgaacatg ttaagaaaat
     8221 gaaataggtt tgtattttat ttatataaat tttaatagaa tatgtatagt atatagtaga
     8281 tagaatgtat aaaaatagaa tttaaataag tagctattat tgcagtgaaa tgaatgtttc
     8341 taagtatatt tgggtggaag aatggtggaa gaaaattagt gaaatgtaat tcttccacca
     8401 ttcttccacc caaaaaataa aaactgttca ataagaatta atatacatca attcagatga
     8461 atccaatcaa aatacttaaa taaaagtaat ctgaaaacaa cataattcaa atcaatttat
     8521 tcaaataaac ttcaatttat cttaaatctt aagaaatatt taagaattag gataatattt
     8581 tcttaagatt tatattttat tatatagtta taagggaaag ttacaaaaat gtaagccaaa
     8641 gtaatataac aatttagtca ttgttgagaa agggagtgaa agatattgta taatatagat
     8701 aagtattatt atacaataga ggaagtgaaa atatgtacaa tatattagta gtagacgatg
     8761 ataaagaaat tgttgattcg atagaaatat atcttaaatc agaaggattt aaaatatata
     8821 aagcatatga tggaatgaaa gctttggaaa taataacaga gaatgacatt catctaatac
     8881 taatggatat aatgatgcct aaattagatg gaatcaaagc aactgtaaaa atacgagaag
     8941 aaagaaatat tccaataatt ttaatttcag caaaaagtga agatacagat aaaataatag
     9001 gattaaatat tggagctgat gattatataa caaagccatt taatctatta gaacttatag
     9061 ctagggttaa atcaaactta agacgatatg taactttagg taattatgaa gatacatgta
     9121 aagaaatttt aaaaagtgga gctttggagt taaatacact aacaaaagaa gttaaaattg
     9181 atggtgaaaa cataaaaatg actccaattg agtataaaat aattgaactt cttttagaaa
     9241 ataaaggacg agttttctca atagatgaga tatatgaaaa agtatggaat gaggaaagtt
     9301 ttaattcaga aaatacagta gcagtacata tcagacgaat aagagaaaag attgaaataa
     9361 atccaaaaga accaagattt ttaaaggtgg tgtggggagt tggttataag attgaaaaat
     9421 tttagtggaa aaattataaa agaaaagagt ttaatattta attgcatttt gattttagtc
     9481 atttttacat ttacacaaat gttaggaatt ttaatatgtt ttaatttttt ctctgagagt
     9541 ttaatttact ctatggggat tatgcttttc ttaaacttta ttttatataa aatactgaca
     9601 atgtagatga ggtgggcaac ttggagaaat atagagtatt aaagttagtt tcattaatca
     9661 taatatctat ctcatttcca ttaactatat tgttggtgac aataggactt gctgagccta
     9721 aatacaatat acaaaaaact tctacaaaga gtgggatttt tgatatatct gatgattttt
     9781 atgatagtaa tatatttgac gaaggaacaa tggcaagtct attacccaag tttaagctat
     9841 ctgtaggtgg taaattaact agtaaagaaa aaggtaaatt ccaacaagaa ggtaaaagta
     9901 tagatttaag tagtagtgat tctgagtatg ataaaatcat gattaatgaa caagcttctg
     9961 aagaatattt aagttatcta aaaaatataa aagtgtatgt tattaataca tacacaggag
    10021 tattttatac aaatacgtca tatgctagtt tatatgattt taaacaaaaa actaagagct
    10081 attgtaatgt agagataata aataagatag gaaagagctc atatattaaa acaataaatg
    10141 gagaaaaatt tgaactgaat aatctgagtc tggaactaaa tgaagtagat gaaggttttg
    10201 aggcatatgt atcttttcca gaagagccaa ctatagaaga tggaatagta tatactaatt
    10261 ttcaaatatt taaacaagct acagaaaaag taagattatt ttttgtagct agtttaagtt
    10321 tagcaattat atgtttatta tctataattt tatatatcaa aataaaaggt gaagttttaa
    10381 aaagaaataa tgtattttta ctaatataca gtaagatacc tatggaattt aatgtaatat
    10441 tagtatctat ttcaattgca attttaacta tatatgctct tgctgtatct tatcatattg
    10501 atgtaattgc attagtttct ttatctttac tgatagtatc aaataatata ttttttataa
    10561 atgtgcaatt gagttattta gaaaataaaa tgtgtatatt taagacaagt attatagtaa
    10621 gagtgatttt atggttaata aaaactgtaa gggaggtcag taacgctata aagaaagtat
    10681 ctttagcaag gaaagttatt gttatagtga taatatcttt agctttaatc atggtaatta
    10741 gcactcgaag tataggtatg ggattactgt tttctatatg tattttttta ggatttacaa
    10801 tatatataac taaaagactt tcatatctta gttacgtaat agaaggtaca gaaagaataa
    10861 aaaagggaga attagattat aagataaaaa ttactgggaa tgataatttt acgtctttag
    10921 ctgaaaatat aaataatatt ggagaaggtc ttgatagagc tatagaagag caagtaaaaa
    10981 gtgaaagaat gaagtctgac cttataacaa atgtatctca tgatttgaaa actccactta
    11041 cttctataat aaattatgta gatttaatta aaaaagaaga atcaatacaa ccagagtata
    11101 taaatgatta tataaatgta cttgagtcaa agtcaaaaag actaaaatta ttgatagaag
    11161 atttatttga agcgagtaga gtaagtagtg gcaatataga attacaaatt agcaagattg
    11221 atttagtgca actattaaga caaagtatag gtgaacttga agaaaaatta tctaaaaata
    11281 atttatattt aaaattaaat gttccaaatg ataaggtgta tatatgggca gatggaagaa
    11341 gaatgtatag agtatttgaa aatcttttat ctaatatagc aaaatattcc ttagaagaaa
    11401 ctagagtcta tattgatgta tatgactatg gtgaaaatgt aaaggtaact atgaaaaata
    11461 tatcttctta tgaattaaat tttgacccaa gtgagattat ggaaagattt aaaagagctg
    11521 atgaatcaag gaatactgaa ggaagtggat tagggcttgc tattgcaaga gatttagtag
    11581 ctttacaagg tggaaaattt tatatagaaa tagatggaga tttatttaaa gcaaatttag
    11641 agtttcaaaa atatgaagaa gaaataacaa atatggaatg agatagtatt taagtatata
    11701 tatttttttt actgtcgaaa gcttttatta taatatatta gaatatttac agtagagaat
    11761 gaagagtaaa aacagagtaa ctttaagtca ctctgttttt tatttaaaat caataatata
    11821 acaacttaaa ttaaaattgt acacatagtt ttaaaataac ttatacaata aaacattatc
    11881 caaatatcac aagataattc caaataaata tatagatatc actcctgtaa taatagaaat
    11941 accaatagat ttaaacttat atgcaacaag aagtacaatc ataaaagata taattttagg
    12001 gttagctata gataaatata gactatctcc attaaaaaat acatctttag cagttaagga
    12061 agtaagtatt gctacaggta taaatttcat gatttttttc aaaaaatcag gcatctcttt
    12121 ttttgaaaaa attaacatag gaagcactct tggtagatat gtaacaatgt acattccaat
    12181 tataataaaa aatatataat tattattcat aagattcctc ctttttacag taagattctt
    12241 ctataaagaa accaattaaa gatgctaaaa ttgatgcaac tattattact aaattgcttt
    12301 tgaataatgc atataaaata acagaaataa tgattgatga tataaatact acaatataaa
    12361 tcttattttt tatttgagaa actattaaag ctataaacat agaagtcaat atgaagccag
    12421 aaatagaact gtctatagat atactttctc ctaaaaatgc tccaataaaa ttagctaaaa
    12481 ctgatgaaat taagcagaag aaattaagat aaatagcatt tctatcagac caatttccag
    12541 cagtaaattt ttcataatta actgcaaaag tttcatctgt tatagtatga caaaatggca
    12601 atataaattt tggactttta ttttttatgt acatgttcaa attagaactc attagaaaat
    12661 gtcttaagtt aactataaat gtagtcaaaa caatagatgt tacacttgca ccagtagaaa
    12721 tcattgaagc tgcaatgaat tgagaacttc ctccaaatac taaagttacc attagtgcta
    12781 tttgaaaagg tgaaagacca gatttttgta atagtattcc tcctactata cctataggta
    12841 tataacctaa gaatatagga attgaagcaa taaagctttc ttttaattgt tgagttcttt
    12901 ccacaataaa tcactccttt tgtattaaat gtattaaagt attagtaaaa cagaaaaata
    12961 gattaattgt ataattgcaa ttataattaa aaataaattt ggattaatat ataaaatact
    13021 atacaacaaa tagataatct taaacggtta ttaaatttta tctatttgtt attatgatgt
    13081 aataatacac attaatctct ataagttaat tactatctgg tgtaatttta ttttaacaac
    13141 aaaaaaaaat acacacaatt aaaatattgt gtgcaataca attatttttt ctcttctaat
    13201 agtcttttta atacgctcag accagcttta agttcttctg tactttctgt agcacataca
    13261 gctattctta ttgcagaaat tggtttttct tttccaacag caaaacgttc agaagcatag
    13321 acctgtacac cttctttaag tgcttgtatc tcaaattttt ctgccattat tccatcaggt
    13381 agaatcaacc atctaaatat acattcttca tttcccaaaa gattatatcc agataaatat
    13441 tgattaataa tcttgtttct tcttcttgca gatttacggc gtgcattaat taatttatcg
    13501 gcttcacctg atgtaatcat gcgataagca atttctgtta aaaaataaga ttgagataga
    13561 ttaatgttgt ataatgcgct tgataatgcc tctcgatact gtttaggtgt agagatatat
    13621 gctagccgta aactaggtgc aataattttt gataaactcg taatataaat tgtttgattg
    13681 ggcagatagg aagccactgg atttaaatgt gtttcattaa gtaaactatg aatagcatcc
    13741 tcaataacaa ttaaattgta tttagatgca atatttgcaa tcatttttcg tccattttgt
    13801 gacattatat gtgtagttgg attttgataa tctggtatta tgtatagacc tttaatattt
    13861 tcatttttac aagcatataa tagtccttct tcactaatct cattatcttc ttgtttaatt
    13921 ggaattagtt gaatcccaag cattttagct gctgtcttta ttccaggata agttaatggg
    13981 tctacaccta ttctatctcc atgttgaaac aaaccagcta aaatagcaac aattgcattt
    14041 tgtccaccac ttgcaggaag taagctatct gatgtagttt caagcccagc tttataaatt
    14101 aatttggcaa tagcttcttt ttgccattta gcaccatctc tttgtccata ttggaatatg
    14161 gttttaaaat ctatttcctt aattatgtgt ttaaacaaag tattcatttc ttctagcgtg
    14221 aaatctggat tcattgtgcc catttcaata aatgtaattt tattattact ggacatcaag
    14281 aatagatttg aacgcgtatc ataagataca aaagttccac ttcctgtaac tccacttatt
    14341 agaccttttt tttcacaaat tttaaaagct ctagagatag tactcacatt aacatctaag
    14401 aaatctgcca attcacgttg gggtggtaat ttagtacctg gtaataaaaa tccattgttg
    14461 atatcttgtt ctagttgttc tgcaagcgcc ttatataata tttgcccttt tgaaggtctc
    14521 tttggtttcc agttcatagg ataattttca aaagaattaa ttggcataag ttttcacctc
    14581 acattattaa tttgattttt tctttatcta aaacaataaa ttctaaagat acaaataaaa
    14641 actgatagga aataattcta tcagtttttg tcttttaatt gatttcaaat cttcctataa
    14701 tttttatacc ttctttatca taaagaggga ttgttttttt aaatatatta aaatttcttt
    14761 ttcttgtata taaaacagct tcttctggtg tctttggttg attatcacaa tcgtacaaat
    14821 ctcttttttt aactaaaaga aataatacat aaaattatta ttgctaatga tactcttaat
    14881 gtggtatata gtcatagtgt cacatgttta tcaatagttt tttcagtaat tattgtaacg
    14941 aatagtagga ctcataaaat acttagaaat atgtttttag ataaatttta aatatataat
    15001 ctaacttata tctataaatt aacactatta ttctccaatt ccatttctag tttttttata
    15061 aatttattaa attcttctgg ttgccttttt ccaaacaata ctcttacaag agctgaattg
    15121 atttttccaa atatattcct cttgctctca ctttcaataa aaataagttt tgtattttct
    15181 aagtcaatat gtactaattc atatctagta atagtacttt ctcttttatt gcttgttttt
    15241 atctcatata ctctattttt ttcgaaatta gttatttcaa ccttaaatct tttattattt
    15301 ttttgttgta caaatgttcc tactgctttt ttctcattaa aattaggaaa atttagtctt
    15361 gcagatttta taaatatatt aaatatgtct tttgcagaat attttaataa aacttcagtt
    15421 ttaaatgcat tcatatcgtt ttcccttctg tatataaatt taatatttat aagttaattt
    15481 ttaagttaaa atagtataat atgccatatt aaatcatgtt aaaactattt atatagctaa
    15541 aatcttacct atataagtat gtatactatc atataaaaat aaaatcttaa aatagaaagg
    15601 gttaaaaaca cagtttatta taatttttat tgttgagtag atacgtacta ttatatatga
    15661 ttgagcaagt ttttcaatca taaatttata aagtattttg cattaaaatt taaacaaaga
    15721 gttaaattat ttaaggttat gaataactaa tacatttagt aaattactaa atatacaaaa
    15781 tgtaaatact tatcaaaatg tataaatact tatgacatct agttacttac agggtttaag
    15841 tagaaaaaaa tatcaaagta agtatggcat gatagttgct tatatattta tcaagaaagg
    15901 agttattaag catggagttg agagataaac ttgtaaacat cataaataca gaaaataaaa
    15961 aagatccatt aacagatgtt caaatagcaa agtttttaag tacaactaga gagaacataa
    16021 ctaatttgag aaaagaactt aatataagta attcaaggca aagaagatat ccttatttaa
    16081 aatcagcaat ttcggcaata ttacaaaaga ataagaatat ttctatatca gaaattacaa
    16141 gggaattgat gacagaaggc tttaatatat ctagaagagt tgtggaggaa cttttaccta
    16201 aagaaagttt agaaatggat gtagtagagg aatctgaaga agaatcgaat gacccatttg
    16261 aaactctgat aggtaataaa gggagtctta gaaatgctgt agagcaggct aaatctgcta
    16321 tattgtatcc accaaaaggg ttaccaacgt tgattattgg ggaaagtgga gttggtaaga
    16381 gtttattttc tagacatatg tatgagtttg caaagcaaaa aaagatagta aaagagagct
    16441 ccaattttgt tgtatttaac tgtgctgatt atagtgacaa tccacaatta ttattatctt
    16501 tgttatttgg atataaaaaa ggtgcattta caggtgctga atatgataca ccaggtcttg
    16561 tagaagaagc tgatgaagga gttttatttt tggatgaaat acatagattg cctccaaaag
    16621 gtcaagaaat actattttct atcttagata ggggaaagtt taggagatta ggtgaaacta
    16681 atgctgaaag aaaagtaagt attatgttga ttggggcaac tactgaaaat gtagagacta
    16741 atttattatt aacattcaga agaaggatac caatgctaat aactttgcca ccattacatg
    16801 atagattact aaaagagaaa atagacctta tatacaatat ctttcaacaa gagtgtaata
    16861 gaataaatgc aaaaatattt gtagataaaa atgtgattga aatacttgca ctaaaaaagt
    16921 ttagtggaaa tataggacaa ttacaaaata tgattcaggt tctttgtgca agagctttta
    16981 tgaagtttat aaattccaaa gatgaagata gtgaatcgat agtagtagta gatataaatg
    17041 aagttttaaa gcttaaagat tcttttaaag atgctgcctt tcaagagatt gaatatacag
    17101 agataagaaa atatttgaaa aatgctatat ttataccatt taatttagaa gaatcatcaa
    17161 taaaaggaag tcttttaagt gatgaatata tattaccaga ggacatatac aaaacaattg
    17221 aaaagaaata ttatgaccta aaatccctag acattgaaga tatagatata gagaatattt
    17281 tatggacttt tattttaaat agatttgctg acttaaagtt taatctcgat agtaatgaag
    17341 aaattttttc aatgagtgat ttaaatagtt ttgtaagtga tagtttagtt aaactggtaa
    17401 aagaacttat gaatgatata gttgaaaaaa atatgaattt agaagtaaat aaaaatatgt
    17461 tcaaatatct agcaatacac ttagaagaag ctataaaaag aattaagcta aatcaaaaga
    17521 taataaatgt aaatttagaa aaaataaaga ttgacttttc aaaagaatat gaaattagta
    17581 aaagttttgc aataaaaatt gaggaatcaa ttggtattaa gattccagat gatgaaattg
    17641 gatttataac actctacata aagtctgctc taaaaaatga agtgaaaaaa gataaagtag
    17701 ggttaataat aatttctcat ggacgtatag ctacagagac tgtaaatgta gttaaagaac
    17761 ttttaggtgt aaagtttcct gtggctatag atatgccttt agatgaaaaa ccaataaata
    17821 tatacaataa ggcagtagaa ctgtcaaaaa taatagacca agggaaaggc atattgtttt
    17881 tggtggatat tggttcactt acaaacatag gtcaaatagt aaataagaga accaatataa
    17941 gcactaaaac tattgataga gtagacctcc taatggcact agaagcaact agaaaagttt
    18001 ctatgggaga ggaagaactt gatgaaatat ttttttcttt gctaaaagat aggatgggat
    18061 ataactatga attagaaaaa cacatagata aatcaaatgc aattataaca ttatgtctta
    18121 ctggagaagg aactgctaag tatataagta aaacgttgga agaaaagtat gataacatta
    18181 aatgttatca aatgagtgca ttggatgaaa atttattttg taaaattgaa aatctaaaag
    18241 agacaaacaa tatattagct attgttggga caataaaccc taagatacca ggtataaatt
    18301 ttatacccta taataaagaa cttttcaaaa atttggatat ctatctatca aaatcaaaac
    18361 aacaagatga cagaccagtt aaatcgtatg aaagaatgct tgatgaggat ttagtgattt
    18421 ttgaaccaga tatatatttt aaaaaggatt tattagaata tgtatgttca attcttataa
    18481 ataaagaata tgtagaaaaa gattacttag attctatttt acatagagaa gaaatgcttc
    18541 caacatattc taaaggagct ataggtgtgc ctcatggaga ttcttctact gtaaatagta
    18601 caaggtttgt ttttgttaaa ctaaagaatc ctattgattg gggtgtaggt aatgtaaatt
    18661 tcatatttat gccagttttt caggctaatg ataaagagat tgttaaaaat gttcttgaga
    18721 tactaaaaga tgcagaattt atgaacaatg ccaataagtg ttttgataaa gatgctttta
    18781 gaaggattat atttgataaa tttaaacatc tgtagccata gcaaaaaaat tgagaggagt
    18841 tagagtaatg aatgtagatt taatatcatt gggtttagaa tctaatgatt atgaaagtgt
    18901 tattgaagaa ttaggaagta taatgtgtaa aaaagaatat gtaaaagaaa catacataaa
    18961 tgctgtcttg gaaagagaaa ggacattacc aacaggtcta gatattggag acatgtgtgt
    19021 tgctattcca catacagatt caaagcatgt aaatgagtct aatgtagctg tagggatatt
    19081 gaaaaatcct gtaaagttta attcaatgat agacccaaaa gatagacttg atgtagaact
    19141 tgtattttta ttagcagtaa agaacccaga ctcacaagta aaactgttaa aagatttaat
    19201 gtcagttttt caaaatataa agttattaaa aaatataaaa aacgcatcaa caaaagaaga
    19261 agtagctaaa ttattggact ttatagaaat ttaatgtagg agaattttat aaataaaaaa
    19321 ttaaaattta aacaatcaaa gtaagtatta tttttttaat aggtttaatc ttatataaaa
    19381 taaaaattta gagtgaaaaa ctaggaggaa attattatga aacaatttaa tgtattatca
    19441 gtttgtggtt cagggacagt tacatcatct atggtagcag gtaaattaaa agaagtacta
    19501 ggtaataagg ggatttctat tactacaaca gaagctagac caacagaagc actaaattta
    19561 gcacaatcag gaagatttga ctttataaca tttacgagtc cacttcaaac aggcgattat
    19621 ggaataccaa ctataaatgc atttgcttgc ctaactggta taggggaaga ggcattcttt
    19681 gaagaagttt tgactgttat tgaagggata gataagtaag ttttggagac gtgaatttat
    19741 agtatttaaa tcaatgattt agatactata ataagctaat attaactaaa tatttgtgga
    19801 aaaaacattt tatatgttgt cataaattaa aaaattataa aaatagtcac ttaagtatta
    19861 aattaagctt ataaatattt ataagtagga gggaaaaaga tgttagaatt tatgaaatct
    19921 ataatcgata catttggttc tgcaattata gttccaatta taatattcat aatagcaaag
    19981 atatttaaag taactactaa gaaatcgttt ctttctgctg tgtatgcagg agttgcttta
    20041 caaggtttta cactgatttt aaattcattt acaccaataa taacaccagt tatcaatagg
    20101 atggttgaga gtacaggagt aaatctacca gtttttgatg ttggttggca agcaacatca
    20161 ttggttgcat tttcaacaag tgcaggtatg atatatttag gtcttggtat attattacaa
    20221 acaattttat ttttgataaa atggacagac gtgtttcaac catcagattt atggaataac
    20281 tattcttata tggtatgggg agcaatggtt ataggagtaa caggaaattt tcctttaggt
    20341 atagcatgta tggttttatt aaacctatat agtttattaa tatcagagtt agttgcaaag
    20401 agatggtcta gttactatag atatcctaat tgtacaataa tagctatgca taatgttgaa
    20461 gcttctgtgt ttgcagtatt tgcagaccct atatacaata aattgggatt aaataaaata
    20521 aaattaaatc caaaagaatt agagaagaaa ttagggtttt taggtgaacc aattacttta
    20581 ggtctttttt taggtatgtt tataggtata ttaggtaata tgacgagaat aaatactatg
    20641 gaagcttggg gagaaataat gaaagtaggt atatctacaa gtgcagtgat ggcaattttc
    20701 cctaaagtag caagtatgtt tgctcaagca tttgcaccta taacagaagc agctagaaag
    20761 attatgcaaa aagctggaaa ccgtgagtgg tacatagcag taaatgatgc tgttggatat
    20821 ggtgaacctg caactttaat atcaggtctt atattaattc caataatgct tgtaatagct
    20881 atggtacttc ctggtaataa ggtattacca gttgtggatt tattggcaat tccatatatg
    20941 gttcaaggtt tagttgccat acataatggt aatataccaa aagtattagt ttcaggtata
    21001 atttggtttg gattaggatt atatgtttgt acatctacag caccattatt tacagatatg
    21061 gctacaaata taggtgtagc tatacctgca ggagcaatgt taataacaag ttttaatata
    21121 ctaggaaaac ctttgatggg attagttttc tttgcatttc taagtgcaaa tccaatttat
    21181 ataggtcttt cagttgtaat ttactttgtt ctatgggcat tgtttagaaa gaacaaaaca
    21241 agtattcttg attatttaga aaaacaagca cttaaaaatg tagaagaaga gcctgtagca
    21301 gtttaagttt ataaaaatga aataaaaata attaaaggag tttataattg attttatata
    21361 agtatcagat aatacctgag aaatatttaa atgaaatata gacttctttt tatttgataa
    21421 tatttgtaat tataatgcat tgtatcttta tagttgagtt ttctgtataa cctgctattt
    21481 aaaacatact cttttatatt tatacagtaa tgtggtttaa ttttataaaa tgtaatctct
    21541 acgggtaaaa gactttgtat ataaggcatt tgcctgaata aaccatttat cttttgtatg
    21601 gcatagatat tgctatatag aagtatatag catgaaagga gatatttata tgggaaataa
    21661 aatgagagca tcagtattgt ataatgtagg tgatgtcaga tatgaaatgg tagatatacc
    21721 agaaataaca gatacgcaag tgcttgtaaa tgtaaaatat gttgggatat gtggttcaga
    21781 tttacctagg tctatggtaa gtggtttgag tggaaataca aaatatccat tgattttagg
    21841 gcatgaattt tctggtgaag ttgttaaaat tggagaaaaa gtaaagcata ttaatgtagg
    21901 agatagagta gctgttgcac cattagtacc ttgtggaaaa tgtgattatt gtaatgaagg
    21961 taattttggc ttgtgtgatg attacaatat aattggaaca agagtaaatg gagcgtttgc
    22021 agaatatgta agagttccag aagaacatat tttaaaacta ccagatacat tggattatga
    22081 aactgctgcc ggaattgaac cagcaactat agcttatcat gggatttcaa agtctaatat
    22141 tagagtagga gatagtgtag ttgtgttagg atgtggtcca ataggtcagt ttgttataca
    22201 atgggcaaag gtgtttggtg catctaagat tatagcagtt gatatttttg atgaaaaatt
    22261 agaactttct aaacttctag gagcaaacta tatacttaac tcaaaagaag taaatgtaat
    22321 caaagaaata aaaaaaataa caaatggtgg tgctgatgtt gtaatagaga ctgctggtag
    22381 ccgatttaca caagaacaat ctctatttgt agcaaaaaag agaggaaata tagtgtttgt
    22441 aggtatatca cacacagaat taccacttag tgcagacgct actgagtgta tattacgtgg
    22501 agaacttacc ttgaaaggtt cttggaattc atatacaagc ccttatcctg gaagagcatg
    22561 gactgcaaca ttggatttta tgggaaaagg tgacattatt tttaaaccca tgatttcaca
    22621 taaaataggt cttaatgaag ttggtgactt tttaagtaaa atgagcaaga gagaaattaa
    22681 tttcaataaa atcctagtag aaatataaaa atttaataaa aaattctaaa agcaattaaa
    22741 ttttataact atgacattaa ataaaataaa aataattttc ttaaataaaa tataggagga
    22801 agaaaagtgt tagaaaattt aaaagaagaa gtattaaaag caaacttaga attacctaag
    22861 aaaaagctaa ttacttatac ttggggaaat gtaagtggaa tagatagaga aaaaggatta
    22921 gtggtgataa agccaagtgg tgtagagtat agtaatatga ctgtagaaga tatggttgta
    22981 gttgatttag agggaaatat agttgatggc aaattaagac cttcttcaga taccccgact
    23041 catctagttt tatataaaga gtttgaagaa ttggggggaa tagtacatac acattcaagt
    23101 tgggcaacaa tttgggctca aataggaaaa tctataccat cttgtggtac tactcatgca
    23161 gattattttt atggaagtat accatgtacc agaaaaatga ctagagaaga aatttgcaat
    23221 gaatacgaaa aggaaactgg aaatgtaatc attgaagaat ttatgggaag aaatccaatt
    23281 cattgtccag gaataattgt aaatgaccac ggacctttta catggggaaa agatgcaaat
    23341 gaggctgtac acaatgcagt agttttagaa gaagtcgcaa agatggctta ttatacagag
    23401 ttaatgagtc ctgataatat tatggataag gttcttatga ataagcattt ttcaagaaaa
    23461 catggaaaaa atgcatacta tggtcaaaaa tgattatctg gaggtgaatt atgctagact
    23521 ctttaaaagg taaaattgtg gaaatagcaa ttaaagcaga gcattatggt ttatgtaaag
    23581 aaaagactgg taattttagt attagagata aggatactgg atatatactt ataaccccat
    23641 caggtatagg aagagaagaa ttaaaagttg aacatatttg tgtattggat ttggatggaa
    23701 atgtaataga agttgagaaa ggtattaagc caagtagtga ggtattgatg catattgaaa
    23761 tatacaaaac aagagaaaat ataaatgcca tatcacatac tcattcttta tatgcaacag
    23821 cattttcagt agcaaagaaa ccaattatac caattgtata tgaatcagtt aattatggcg
    23881 gttatgtaga tattgcttca tacgaaagac caggaacttt aaaattagct aagagtgttt
    23941 caaaattact gatagataca gatgcatgct tattagaaag acatgggttg acaactgtag
    24001 gtaatgattt agacgaagca ttattaaaat caagatatgt ggaagaggta gcagaaatat
    24061 actataggtc tttagtatta aatcaattta aagaacttga agtagtagat gttgatgagt
    24121 ttaaatcttg gaaataccca gaagaaataa agttttaatc taaataattt tcattgaagt
    24181 ggttaattaa aatatatgta ttatttatat caattactat gttttattat attaattacc
    24241 gtattttgta aatatattta ttacattttt tcaaaaaaat atagaatccg aaagccatat
    24301 aaaattgact tgggattcta tactttttat ttatgcattt ttctttatct gattttctgg
    24361 agaatttata tgttcaaaat attttttagt ttcagatact attataggtg ataatgcaag
    24421 taaagctata aggttaggta ttgccataag cccatttaca atatcagcaa ttatccaaac
    24481 aacttctaac tttaagaaag cacctaataa caccatagcc acaaatacag ttctataccc
    24541 attcatgcct tttacaccaa acagaaattc aaaacatctt tctccataat aactccatcc
    24601 caaaattgta gtaaatgcaa ataatgttaa actaactgta agtaatattg gtccaaatgt
    24661 aggaattgct ccgttaaaag ctgcttgtgt cataacagct ccatttaggt ctgaacacca
    24721 cactcctgaa ataacaagag agaatccagt aagagtacag attataatag tatctataaa
    24781 agtacctgtc atagatataa gaccttgttc cgctggccat tcagttttag cagcagcagc
    24841 agctattgga gcactaccta gaccagactc atttgaaaat acaccacgag cgataccatt
    24901 tctaattgct agtgacatag ttgctcctaa aaaaccacca gtagcagcag taggtgtaaa
    24961 tgcactttta attattaaca taaaagtttc agggatttta ttccaaaaag atattaaaat
    25021 gattccacag attacaacat atataactgc cataaaaggt actattttag tagctacatt
    25081 agatatactt ttaagtcctc caaatacaac taaagctaca aatactgcta atacaacccc
    25141 tgtaattcta gggtctatcc cgaaactatt atttattgca tctgttattg aatttacttg
    25201 agtaaaagta ccgattccta aaagtgcaac tagtatacca cttatagcga aaaatattgc
    25261 aagaggtctc catttttctc ccataccatt tactatgtaa tacattggcc caccagacac
    25321 ttggccattt ttatctttag ttctgtattt tattgcaaga acaccttctg aatacttagt
    25381 agccattcca aagaatgctg ctatccacat ccaaaaaagt gcaccaggtc caccagcttt
    25441 gatagctgta gcaacaccaa caatattacc agtaccaact gtagcagcta gagcagtaca
    25501 taaggctgca aaacttgaaa catcaccact acctttgttt tcagcagaga atattaactt
    25561 aagagctctt ggcagtttag ttatttgaac aactccaagc ttaacagtaa gtagtatacc
    25621 agtaccaact aatagtacca gtaggggtgg tccccaaata aaagcatcaa ctttgtttaa
    25681 aatatcaatt agattcataa aaacactccc tcattttttt tgctttacat aatcaataga
    25741 atttttaatg aagtaattga caggaaataa gtataattta ttaataattt ctagtgtaat
    25801 aaaaaaagct aaatctaaaa aagattcagc tctggatgta cactaattag caaccaaaat
    25861 aaaagtatta gtaaatactg tttttggtag ataatccctg tccttttgcc tgagagattg
    25921 agcataaaag ccttgcccct tcggcgccca taatgggtct ctccagagtt ccgtaaattt
    25981 tacagtccta cttttaaaag tacctgagag tgttactcct tcggtgtgct atatagcaac
    26041 tcttctataa aatcttaacc ggatattgat ttgtcatagc ttattgtatt aataatatta
    26101 atataagttt ttatgttttg tcaactaaaa aattaaaaaa caaagaaaaa atataaaaat
    26161 gtaagcctat ttacgaatta taaacttaga aagatgagta atatacgtga aaatgaattt
    26221 tgtaatacac atacaaatga agtgtaaaat aagttttaaa taaaaaaata ataaaatctt
    26281 aaataattaa ttagatatga ttaaattatg gtaatattat agttacgata ttaagaaaag
    26341 ttctatttag ttagatttta agcgtaatat gagattatgt atagagaaag gatgtatttt
    26401 tagatgggaa aaatattagt gctagcagag aaaccttctg ttggaagaga tatagcaaaa
    26461 gttttagggt caaaaaatga aaaaaatggt tatatagagg ggccgaagta tgtgataact
    26521 tgggcactag gtcatttggt tacacttgct gaccccgaaa gttatggaga aagatataaa
    26581 tcatggagct tagaagacct gccaatactt cctaagtacc ttaagactgt tgtaataaaa
    26641 aagagtggaa agcagtttaa tacagttaaa tcgcaaatga atagaaatga tatagatgaa
    26701 atagttatag caacagatgc aggtcgtgaa ggagaacttg tagcaaggtg gataatagaa
    26761 aaatcacagg taaaaaaacc tataaaacgt ctttggattt cttcaagtac agacaaagca
    26821 ataaaagacg gatttgcaaa attaagaagt ggaaaagaat atgaaaattt gtattactca
    26881 gcaatagcac gagcagaagc tgattggatt attggaataa atgcaaccag agctttgaca
    26941 acaaagtaca atgcacagct ttcttgtgga agagtacaaa ctcctactct tgcaatgttg
    27001 cttaaaagag aagaagaaat aagaaatttc aaacctaaag agtattatgg attagaatta
    27061 attgctacaa agggaaattc agatataaaa tttatttgga atgataaaaa caataattct
    27121 tcaactttta gtaaagaaaa gatagaatcc acattaaaaa aagtaaaagg tgtagacata
    27181 aaaatatctg aagtaaacaa gtcatataag aaaaaatatt cacctgcact ctatgattta
    27241 acagaattac aaagagatgc aaataaaatg tttggatttt cagcaaaaga aactttatct
    27301 ataatgcaaa aactgtatga acatcataaa gtacttactt atcctagaac tgattctaga
    27361 tatttaacat cagatattgt tggaacatta aaagatagaa taaaagctgt aaatattagt
    27421 gattattcaa agatttgtaa tagattatta aaaagcaata ttatagctaa taaatcgttt
    27481 gttgacaatt caaaggtaac agaccaccat gcaataatac caacagaaca gaaggtattc
    27541 atgagtgatt ttagtgataa agagcgaaaa atatataatc ttgtagtaaa aagattttta
    27601 gcagtactat ctcctccttt tgaatatgag cagacaacta taagtgcaac tgtagaagga
    27661 gaaatattta aggctaaggg aaacaaagta ataaatttag gttggaaaga aagttataaa
    27721 gatattgaag atgaagatga gtatgaaagt ataccaaatg ttttagaaaa agatgtactt
    27781 aaggtcaagg gattaaagat aacttcagga aaaacaaatc caccaccata cttaaatgag
    27841 ggaacattat tgactgctat ggaaaagaat ggtctaggga cagttgctac aagagcagat
    27901 ataatagaaa aattattcaa ttcattttta atggaaaaga aaaataaaga tatatatata
    27961 acatcaaaag gaagacaatt attagattta gttccagtag acttaaagac accagaactt
    28021 acagcttcat gggaaaagaa attattggat atttcaaagg gaaaacttag taaaaataca
    28081 ttcataaatg acatgaaaga ttattcaaaa gatattgtac tagaagtaaa aaatagtgat
    28141 aataaattta aacatgataa cttaactaaa aatagatgtc cagaatgtgg aaaatttatg
    28201 ttagaggtaa atggtaaaaa aggtaagatg ttgatttgtg aagatagaga atgtaatact
    28261 agaaaaacta tatcacaagt aaccaattca agatgtccta actgtcataa aaaattagaa
    28321 cttcgtggag aaggtgaggg gagaatcttc acttgtagtt gcggatacag agaaaagttg
    28381 tcttctttca acaagagaaa gcaagaagaa aaacagaagg catcaaaaaa agatgttaat
    28441 caatatttaa aaaatcaaaa taaaaatcaa gagacattta ataatccatt tgcagaagca
    28501 ttagctaagc taaaaaacaa ataattttaa agttattatt atacacaatt ataactttaa
    28561 ctgtatatta gttatatgta ctgatataat atagtgtata gtttaggcat gaaagtaggg
    28621 ctgttaaatg gatttaagtg gcatatttaa atactattgt aaagagtgtg aaaatacatg
    28681 gaataattcg agtgttgaat tatttgagaa tatagaaacg tatagtaaag attcacaaaa
    28741 aaagagggaa aaagaattag ataaattgct aaatacaata tcagttcatt tagagaggta
    28801 tccaagtgat gctgtattga gaaaaatgtg ggtaaaaaag ggcgaggttt tcttacaaaa
    28861 gacattggaa aaagaaaata tttttaagtt agaaaaaatg gatgtagagg atagaaaaaa
    28921 atttttagat ataacaaaac agtttattag agatgctaga aaatttgatg atgatttacc
    28981 tataggtgat attatgcaag ctatgaggaa tgtatggatt tcaaatgcat tacaattatt
    29041 atttggtaaa gaagtatatt attcaaaagc taactttgca tatagtatgt tatatccata
    29101 tactgataat tatttagaca atacaaatat agataaaaat gataagattt tatttaataa
    29161 ctggttagaa aaaaggctcc tgggagaaca cattaaatct aaggattatc atgaaagtaa
    29221 agtatctcaa atgatagatt atattgaaag tgtataccct agagaaaagt ttacagaagt
    29281 ttatgaatcg ttattattaa tatttaaaag tcaagtaaat agtttaaaac aacatggtaa
    29341 ggaaaattat ttgtgtaaag aagatttatt atccatttct attgaaaaag gaggttcatc
    29401 cgttttagta gatggatatt taataagtgg attgatgaca aaggaagaaa tagagttttg
    29461 tataggatat ggatttttat tacaaatatc tgatgattta caagatataa aagaagattt
    29521 aaaatacaac cataaaacta ttattacaga gatgtcaaaa gagggtactt tagataaagt
    29581 tgtaaataaa ctaataaatt ttactattga gttaatagat agttttaaaa ttaataataa
    29641 aaataaatct gtaataacta tgataaagaa tgattgctta atgttaattt tattttctgt
    29701 agtttataat gctgaatttt tttctgtagg atatataaaa gaagtagaga aatttattcc
    29761 atatacaata gattattcat tagagattga agaaaaaata aaagaaaaat ttaaaaatat
    29821 agatgtttta aataatgaaa atgaatataa agaaatgatt gatattattt gtgcagagta
    29881 gaaaaaaagg gagtgtctta gaatagactt tttagtttat gaggcactct ttttgtataa
    29941 aatcaaatgt attttcatca ttttaacaat taaaaagagc ttatccctat ttgagaaagc
    30001 cctttttaat ttaaataaaa atgtcaaggt taaactattt aaatgcagta ataatcccat
    30061 tatcatgtaa gttttttatg attgtagctg cgatagggaa tccaaataat ccagctattc
    30121 caaatagttg agccccaaca aacatacaca ttaatgttat taaaggatat aggccaattt
    30181 ggtgtcctac tacctttggt tctaatattt gtctaacaac ggttataatt atgtatagta
    30241 ttaaaagtcc tattgctaaa ttaatatttc cattaatgag tgagataatc atccaaggtg
    30301 tcaaaatact tcctgtaccc aagactggca aaatatcaac aagtgctatg atgacagata
    30361 tagtaaatgc attttcaacc tttaggatag taagtccaat aagtagttct atgaatgtca
    30421 ctgatagtag tattgcatag gcttttagta gttttaaaag agcattaata ctgctatttt
    30481 ttatatttat tatcataaat tgactttttt ctggaaattg ttttaagata aagtttacta
    30541 ttttttgata gtcaaaagta aagaaaaaag aagcaattaa agtaataata agttttaaca
    30601 taaatgcagg tgttttactt gcaatactag caatagcatt gagtgcattt gttgaaatag
    30661 aagctactaa agacatcata gattgactta tattatccca accaagtatt aatgctaggt
    30721 taacattagg tgtactagca tctatctttg aaaataaagt atttagcgtt ggttgtatac
    30781 ttgatttata tatttcagga agtctaaaaa atacatcact tacacttgca aatatcttca
    30841 caccaaagct aactaataaa aatatacaca acccataaaa aattaaaagt attactatag
    30901 aaataagtgt acgatttaaa tttgtattat ttgtaataag tcttataata ggtcttaaga
    30961 tggatgcaat gataaaactg attacaaaag gcattaataa tggcaataag aattttaata
    31021 caatatatac aatacttgtt attaaaacta catatgtaaa tttaattata aaattctttt
    31081 gcttttgaat atccataata taaaacctcc aatgtatttg atattattct aaatatggtc
    31141 ttttttacag aaaatatact actgtatatt gattataaac tataaagctt atgtaaagta
    31201 aataaattat gtaaaattta ggttaatttt gtataaagag atacttttat attttacaat
    31261 taataaccaa atactaaaaa atattttaaa taaagaactt aaaattgtga taaaattaat
    31321 ttatagatat taaaaaaagt ataatatatg gtttttaaga ggtgctaaga tgaaaaattt
    31381 tagagattta ggtgggaaca aaactgagga tggcagaact gtaaagaagg gattatttta
    31441 taggtctgca aaattatcaa atctaagtga aaatgatata aagattttaa aagagttaaa
    31501 tattaaatat atatttgatt atagaagtga tgaagaagct cgtaaacatc catcaacaat
    31561 aatatcaaat ataaaaaata taagaatacc agcaatgaga gagctagaag aatcaggagg
    31621 aagttttggt tctattgaag atatgattga tggattgttt gaaaaagatg gtgcatttaa
    31681 tatgttaaat aatagttact ataatttgcc tataaataat ccgtcatata aaaaattagt
    31741 agaacttata agagactatt ctaatttacc aatattaaat cattgtacag ctggtaagga
    31801 tagaactggt gtggggagtg ctataattct tatgatttta ggggtatcga gagagaatat
    31861 aatgaaagat tatctaaaaa gtaatgattt tgcagataaa gagatagaaa gatttataga
    31921 atataagcct aaatttaagg acattccaaa agaaaattta aaatatatat ttggtgtaaa
    31981 tgaagagtat atgaaaactg catttagaag aattgatgaa gaatacatta gtgtagaagc
    32041 atatttatat ggagaattta atttaaataa agaagaaata agaaaattaa gaaatcaata
    32101 tctagagtaa aaggtgagtt tatgagttta aatataacag caagacagat aaatataata
    32161 aaaatattgt taaattcaaa agatacaatt agtggtattg ccttaagtca agagatagga
    32221 tgttcttcaa aaactataca aaatgaaata aaggatatta ataaacaatt tagaaatggt
    32281 aaaattttgt caataagagg agttggttat aaactagaag gaagttttga tgaggtaaat
    32341 ataaatagca atctctatga tgatgtagat agagtagaat atataatcag aaaaatatta
    32401 accttaagta atgaagaaaa aaatactata aaacttgaag atttagccga ttctatgtat
    32461 gtaagtgttt caacagtaaa aaatgattta aaagaagtaa aaagaatgtt ggaaaagtat
    32521 tcaatatcag ttaaatctaa gcataaacaa ggtatatgtg ttttggaaag tgaagataag
    32581 atattaaatt gtatagttga cttaagcaat aagagagata atcaattgag tttaaatgat
    32641 tttttaaatg atgatataaa ggaaagaaaa ctattaataa aaaaattatt attagacata
    32701 ttaaatgaaa atggattggt attaactgat atagaattta agagtgtgtt aaataatata
    32761 ttagttatgt taagcagaca taagtataat gaaaaagaat ttatagagaa ttatatagaa
    32821 aattatagga gcaaaagaag ctcaatttta gaaaatgaac aaaacaaaga aattataata
    32881 aattcaataa aaacattttg taaaaattta aaattagcta catcaataga tataagtaat
    32941 gataaggcat ttgaagagtt tttatataag catattagta gtttatgtaa aaaaataaag
    33001 ttaggtataa atcaatcacc tataatggct caagatataa aaataaaata tccatttgct
    33061 tttgaactag ctaatatagc taaaaagaca atagaaaaag atttgaagat agaaattaat
    33121 gaagatgaag ttgcaaacat agctctacat ataggaggag cagttgaaag agcatcttat
    33181 aataataaag ataaggtttt caaaactata atagtttgta cttcaggcat aggcacatca
    33241 atgttaataa aagctaaatt agagaatata tttaaggaaa aattagaaat actaaagatt
    33301 attccttcat acttagttga atatataaaa gttatagatg ttgattttgt aatatctact
    33361 gttcctattg aagtaggaga tgtgccagta ataaatatat ctccaatttt aagtgagaaa
    33421 gaaattagat taattgaaaa atatatagaa acaggaaata tatacctaga tttagatata
    33481 aaaagcctgt ttgatagtga attatttttt actgatttgg tgtttaaaag gaaagaagaa
    33541 gttatagatt ttatggcaag taaacttgta caaaagggtt atatagatga ggatatgaaa
    33601 aaatcttact ttgagagaga aaaaatagca acaacagaaa tagggaatat ggtaactata
    33661 ccacatggag ctattggaaa aatttttgat aataaaatag caattggtat attaaagaag
    33721 cctatttctt gggaaatatc agatgttcgt ttaataataa tgttagccct tgataaagat
    33781 aaaatattag attatgaagt aatattttca aaaatatata aaagagtaga ttctatagca
    33841 aaagttataa gtatatgtga aaatagtagt tttgaaaaat ttgtaaattt atttaattag
    33901 atgggtagta ttgtatatac acctgtaaat ttggataata taaaactaaa taagataaaa
    33961 acgataaatt tctcttttaa ttaagagaaa ttttttgact ttcaaggata ttaatataaa
    34021 gttaagatat aaacataaag caaataaata aaaaagaggt ggcaatatga tttatacagt
    34081 gacattaaat ccatcaatag attatatagt taagctagat gagctaaaga caggaagtac
    34141 aaatcgtgta aaagaagaat acgtttatcc aggaggaaaa ggtataaatg tatcttgcat
    34201 acttaaggaa cttggaaatg ataatacatc tttaggtttt ataagtggtt ttactggaga
    34261 atatataata agaacattgg aagaaaaaga attgaagaca gattttataa agataaaaag
    34321 tggtttttca agaataaatg taaaaataaa ggcgttaaag gaaactgaga ttaatggaca
    34381 aggtccaaat atagatgatg aagacattga tactttatat aaaaaacttg ataagctaaa
    34441 tcaagatgat attttaatat tggcaggaag tataccatct actttagatg aaaaactata
    34501 cgaaaatata atggctagat tagaaaaaaa gaatataaaa gttgtagtag atgcaactaa
    34561 aaatcttctt cttaatgttt taaaatataa accttttcta attaagccta ataacgacga
    34621 attagaagaa ctatttggtg ttaaattaaa ttcaattgaa gacatggtaa aatatgctag
    34681 aaggttaaag gaaatgggag ctataaatgt cttggtatca atgggaaaag atggagcatt
    34741 gttgattaca gaggaagatg aagtgcttat aagtgatgtt ccaaaaggaa aagtaaaaaa
    34801 ttctgtagga gcaggtgatt caatggtagc aggatttata tctgggtatt tgaatactgg
    34861 gaaatatgat tatgctctta aattgggagc agcttcaggt agtgcaactg ctttttcata
    34921 tgacttagcc aaaagagaat acattgataa attggtaaat gagatatctg taaagcagtt
    34981 ttaaaatatt aaaaaatata tagaaaggta attaatattt atgaaaatta tagatttatt
    35041 agatgaaaag tcaattaagt taaatttaaa ttcaaaaacc aaatcagaag caatagaaga
    35101 attagtagat ttggtcgcaa atagtggaaa tttaaatgat aaagaaaact acaaaaaagc
    35161 aattttggct cgtgaagaaa tgagtacaac aggaattgga gaaggtgtag ctatacctca
    35221 tgctaaaaat tcttcagtta ctaaagcttg tatagcagca gcagtgtcaa aagaaggtat
    35281 agattatgaa tcgtttgacg gaagtttatc aaatctattt tttatgatag ctgcaccaga
    35341 cggagctaac aatactcatc ttgaagtatt atcaagatta tctacaatac ttatggatga
    35401 agactttaga aataaactta taaattcaag ctctgaaaaa gaatttaagg aaataataga
    35461 taaaaaggaa agagaaaaat tcagtgaaga atatcaagat gagaaagtta ctgaaaaaaa
    35521 tataatagat actaaagaga atgatgctaa taagtatcct aaggttttag cagtaacagc
    35581 atgtccaact ggaatagcac atacatttat ggcagctgaa agtttaaata aaatggcaga
    35641 aaacaaaggt gtatcaataa aagtagaaac taatggttca gcaggtgtta aaaataagct
    35701 tacaaaagat gaaatagaaa atgcaacatg tataatagtg gcagcagata aaaatgttga
    35761 gatggctaga tttaatggca aaaaagtcat aaaaactaag gtggctgatg gtatacacaa
    35821 agcggaagaa cttatagaca aggctgtaaa tggagatgct ccaatttacc atggaggaga
    35881 tggaagtcac aacgaatcaa atgaagaaag tgaaagtgga tttagaaaag tatacaaaca
    35941 cttaatgaat ggtgtgtcta atatgttacc atttgttatt ggtggaggga tacttatagc
    36001 gatagccttt ttacttgatg attatactat taacccttca aactttggtt caaatacacc
    36061 tatagcagca ttttttaaag gaataggaga taaagctttt ggatttatgt tacctgtact
    36121 tgctggatat atagcatact ctatatctga tagaccagcg tttgttgtag gatttgtagg
    36181 aggtgctcta gcaggtgatg gtggttcagg ctttttaggt gcactacttg caggttttat
    36241 agcaggttat ttagtagaag ggcttaagaa aatatttagt gtactaccag cttcattgga
    36301 aggaataaaa ccagtattgt tatatccttt acttggaaca cttttgatgg gaattataat
    36361 gacattttta gtaatacctc cagttgcagc aattaataat gcaatggttg gatttttaaa
    36421 tggtttaggt ggaacttcaa aaatagtttt aggattagta ttaggtggaa tgatggctgt
    36481 ggatatgggt ggacctgtaa ataaagcagc atatgtattt ggagttgcat cacttgaatc
    36541 agggcagttt gaaataatgg cagcagtaat ggctggtggt atggttccgc cacttgctat
    36601 agctcttgca actacatttt ttaagaatag atttactaaa gaagaaagag attctggtaa
    36661 agttaattat ataatgggat tatcatttgt tactgaagga gcgatacctt ttgcagctgg
    36721 agacccactt catgttatac cagcttgtgt tggaggttca gcagtggcag gagcacttag
    36781 tatgttgttc aacgcagctc ttcgtgcacc tcatggagga gtatttgtta taccagtggt
    36841 tacccatcca tttgcatata tattagctat agctgtaggt gctttggttg gaatgatgtt
    36901 tttagcatta cttaaaaaac cattaaatca agaagtatag caattaaagg atattcaaga
    36961 acttaaaata tgatgtttta taaaaattaa tatattgctg aattatttta aaataaggat
    37021 tttatgaggc tgttatataa cgatttgtaa ttgttatctt gacagtcttt tatttttata
    37081 taagtaaaat aagtgtgttt tgctttattt gtatttaaat tgtttttaag ttagaatata
    37141 aagaaaatta tatattattt taatattcac tcga
//
LOCUS       DAEQAF010000034        35265 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.035, whole genome shotgun sequence.
ACCESSION   DAEQAF010000034 DAEQAF010000000
VERSION     DAEQAF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35265
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.035"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            766..1617
                     /locus_tag="KRN00_001753"
     CDS             766..1617
                     /locus_tag="KRN00_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH1827619.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            1621..2091
                     /locus_tag="KRN00_001754"
     CDS             1621..2091
                     /locus_tag="KRN00_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827620.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            2104..3414
                     /locus_tag="KRN00_001755"
     CDS             2104..3414
                     /locus_tag="KRN00_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1827621.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            3626..4372
                     /locus_tag="KRN00_001756"
     CDS             3626..4372
                     /locus_tag="KRN00_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1827622.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTADSI
                     SLLIDDGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            4734..6275
                     /locus_tag="KRN00_001757"
     CDS             4734..6275
                     /locus_tag="KRN00_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBH1827623.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKAGISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            6310..7416
                     /locus_tag="KRN00_001758"
     CDS             6310..7416
                     /locus_tag="KRN00_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBH1827624.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGKKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(7626..8912)
                     /locus_tag="KRN00_001759"
     CDS             complement(7626..8912)
                     /locus_tag="KRN00_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1827625.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAISENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(9035..12133)
                     /locus_tag="KRN00_001760"
     CDS             complement(9035..12133)
                     /locus_tag="KRN00_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1827626.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            12837..12989
                     /locus_tag="KRN00_001761"
     CDS             12837..12989
                     /locus_tag="KRN00_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827627.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGATLSFFATTMIAVRQ
                     VKTKKK"
     gene            complement(13281..13985)
                     /locus_tag="KRN00_001762"
     CDS             complement(13281..13985)
                     /locus_tag="KRN00_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827628.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(13976..15583)
                     /locus_tag="KRN00_001763"
     CDS             complement(13976..15583)
                     /locus_tag="KRN00_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBH1827629.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(15837..17015)
                     /locus_tag="KRN00_001764"
     CDS             complement(15837..17015)
                     /locus_tag="KRN00_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827630.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(17241..17735)
                     /locus_tag="KRN00_001765"
     CDS             complement(17241..17735)
                     /locus_tag="KRN00_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1827631.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(17736..18497)
                     /locus_tag="KRN00_001766"
     CDS             complement(17736..18497)
                     /locus_tag="KRN00_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBH1827632.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            19199..22033
                     /locus_tag="KRN00_001767"
     CDS             19199..22033
                     /locus_tag="KRN00_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827633.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNTDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFAETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            22076..23320
                     /locus_tag="KRN00_001768"
     CDS             22076..23320
                     /locus_tag="KRN00_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1827634.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(23735..25477)
                     /locus_tag="KRN00_001769"
     CDS             complement(23735..25477)
                     /locus_tag="KRN00_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827635.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
     gene            complement(25461..26135)
                     /locus_tag="KRN00_001770"
     CDS             complement(25461..26135)
                     /locus_tag="KRN00_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827636.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(26172..27161)
                     /locus_tag="KRN00_001771"
     CDS             complement(26172..27161)
                     /locus_tag="KRN00_001771"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1827637.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     SSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(27209..28453)
                     /locus_tag="KRN00_001772"
     CDS             complement(27209..28453)
                     /locus_tag="KRN00_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1827638.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
     gene            complement(28495..31041)
                     /locus_tag="KRN00_001773"
     CDS             complement(28495..31041)
                     /locus_tag="KRN00_001773"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827639.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIAVYFSNKMINKLSIVSGIKEN"
     gene            complement(31249..31410)
                     /locus_tag="KRN00_001774"
     CDS             complement(31249..31410)
                     /locus_tag="KRN00_001774"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827640.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            complement(31466..32482)
                     /locus_tag="KRN00_001775"
     CDS             complement(31466..32482)
                     /locus_tag="KRN00_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1827641.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            complement(32479..33777)
                     /locus_tag="KRN00_001776"
     CDS             complement(32479..33777)
                     /locus_tag="KRN00_001776"
                     /inference="COORDINATES: protein
                     motif:HMM:NF015983.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1827642.1"
                     /translation="MIDSEEMIFNVEDLIIYRKNQLVIIYNKKFRKYIKLSEEIYKYF
                     LLGQENKIKIYDFVNYFDDESDKKYIINLIDIMNKNQIFKSNNLNFDMLSNGVAIYFC
                     LTNRCNLFCKHCCVESSSNKKDLLSTYDLKNIVDIISVLNTPHIIITGGEPLIREDFF
                     EIIKYIKQKLPDTKLILSTNGTLIDEHNVDFIITNFEKIDISIDGVDENTCSETRGKG
                     VFNKVISSVNLLKDNGFSNIKLSMVFGQKNSHLNKQFKDLNKKLGTEFVERYFIPTGR
                     GLENKESYLIEDTVLPITIPYILDNELKMCKDKKNKKMGCCACNAGNSQIFINYDGDV
                     YPCPSLIKDDYKMGNIFDNEFVKVIKENKTRDLKSLIKLESIYPYNFEKCKDCDVNIF
                     CWHCPAILDSVKDNELELDRWCSMMKHNLNTAVWGDEKVN"
     gene            complement(34243..>35265)
                     /locus_tag="KRN00_001777"
     CDS             complement(34243..>35265)
                     /locus_tag="KRN00_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1827643.1"
                     /translation="GFDSIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLI
                     PLLKFIRLKTKINKRDCIYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTV
                     FLLSNLSLVSIIGRIIKDNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNN
                     HIICIQNVYGKNEFADKYIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNNIYF
                     LVDINFLECNFIEMPDICSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIK
                     CENTKINEVVLKNNKVITSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIY
                     IPLTRN"
BASE COUNT        12157 a         5547 c         4008 g        13553 t
ORIGIN      
        1 tcttacttaa tttacttatt gctatatcaa ttccacttat tatcatctta tttaacttac
       61 ttatttctat atcaattcac ttattattac ctcacttgtt atcatcttac ttaatttact
      121 tatttctata tcaatttact tattatcatc tcatttgtta tcgtcttact taatttactt
      181 attgctatgt caattcattt attattatct cacttgttat cgtcttactt aatttactta
      241 tttctatatc aattcactta ttatcatctt aattcatttg cttattatca tttactttat
      301 tcaatttcta tatcaaaatt agtatttgta cttaatactt aaaattaatt taaagtcttt
      361 acatattatt tattttctat tgtaatattc atttccatac tttactaagc tacttccact
      421 catttatttt aaaatttcaa tttactattt ctcaactcta tattattatt tttcaatttt
      481 atattactaa ttttaaagct ttttagctat tattcctaca atatttaaac aattttttca
      541 taataaagct atattacaat atattcaaaa tatgtaatat tttagatatt tttcgttgac
      601 aatgttaaat ttttgtttta tccttaatta aggacatgtt attgacattt ctgaaactta
      661 tttgaaatag ttttttcatt ttatttagga aaacgtatta tacttaagaa aacgtatttt
      721 ctcatttcag ataagtaaaa tatttattct tttgaggagg aaatcatgga aattaataaa
      781 aaacatttta ttcaagtatt tttaacttgc ttaatcttgg tagtaatatg tgaatttata
      841 gggcaaagaa ctatagctat tggaaaagcc tctatagtac tgttccctat gctttatgca
      901 gttataattg gacttataat aacaccagat ttattaggta aaaaaattaa agcacttaaa
      961 aaagtggttg gagaaaaaga aataaatatt gctggtgaag ttgttggaat tgcactagta
     1021 atgcttggta taaaatatgg tactacagtt ggaccaaaca ttgacaaaat aattcaagct
     1081 ggaccagcat ttatcgctca agaatttggt catatacttg caccaatcgt tgcattacct
     1141 cttgcattaa tgtttggaat gaaaagagaa gctgttggag ctactgcaag tataagtcgt
     1201 gaaccttctt taggagttat atcagaaaaa tatgggataa actcaccaga aggtagtggt
     1261 gtacttggta catatttaat gggaacagtt cttggtacta tatactttag tgtactaggt
     1321 tcaatatcta tttatagtgg tcttcaccca tatgctttgg gaatggcctg tggtgttggt
     1381 agtggaagta tgatgacagc agctgctggt tcattatcta ccatggtacc acctgaaatg
     1441 gcagatacaa tacttgccta tgctgcaaca agcaatatga tgtctagtat aacaggaatt
     1501 atattcttag tttttgtatc cttaccattt actaatttta tgtataagat tttagaacca
     1561 aaattttcga gaaataaaaa aactaaagaa attaaatcta cagaaggaga gtgctaataa
     1621 atgtttgcta atttaaattt aaagaaaagt tcatatcaat tattggttat gtctgttatt
     1681 ggagttataa ttcttatagg acaaagaatt agcgttggta catctatagt tacagctctt
     1741 cctggtatgg tgatgctaat attagctgct atggcagcta tgattataaa agatttattt
     1801 cctaaatcaa tctttccagc ttttggattt gcaactataa tcggcctttt acttagtatg
     1861 ccatatagtc caacatctga agtattctta actaacacta ataatattaa ctttatggct
     1921 ataactactc cactactagc ttttgcagga atttctgttg gaaacaaaat agaagcttta
     1981 aaagaaatgt catggaaaat agttataatt tcacttattg tatttacaac tatattcttt
     2041 gcatgtgcga gtatagctca tatagtttta agtattcaag gtaaaatata ggaggaattt
     2101 attatgaata aagaacaatt aaaatctcta gtaataaaaa ctatagatga aaatagagaa
     2161 aaaatattaa aaataggtca aggaatatac aaaaatccag aatatggata taaagaattt
     2221 aaaactacag aagctgtttc aaactttttt gagcaagaat taaatttatc tgtagaaaaa
     2281 aatatagcag ttacaggatg caaagcagat gcaaattcta gcaagaaagg tcctcatata
     2341 tctatacttg gagaattgga tggtatatca tgtaaagaac ataaagatgc taatgaaata
     2401 ggtgcttctc atacttgtgg acataatatt caaatagctg gaatgttagg tgctgctgtt
     2461 ggtttagtaa aaagtggcgt tttagaacat ttagatggta aagtatcttt tatggctact
     2521 cctgctgaag agtttattga gttggaatac agagagcaat taaaaaaaga aggaaaaata
     2581 acttattttg gtggaaaaca agaattaata aaaagaggtt attttgatga tatagacata
     2641 tctatgatgt ttcatgcttc tgatttagga gaagataagg ctctagttgg tcctgagagt
     2701 aatggatttg ttggaaaaaa ggttaaattt ataggtaaag aatctcatgc tggttctgct
     2761 ccacatgatg gaataaatgc tttaaatgca gcaatgcttg ctataaacaa cgtgaatgca
     2821 cttagagaaa cttttaaaga gtctgaaaga gttagattcc accctatcat cacaaaaggt
     2881 ggagatatag taaatgttgt tcctgctgat gttcatatgg aatcatatgt tagagctaga
     2941 actataaatg gtatgattga tgctaatgaa agaataaata aggctttgat ggctggtgga
     3001 atggcagttg gagctgatgt tgagataact gaaattcctg gatatcttcc aatattacga
     3061 tacaaaagtc ttgataattt atttaaaaac aatcttgaag atttaggtct aaaaggaaaa
     3121 gttattgatg gtggagattt tacaggctct tttgattttg gagatgtgtc tcatataatg
     3181 cctactcttc accctatgat tggtggtgta aaaggagctc ttcatacaag agattttgaa
     3241 atagttgatg aagatttagc ttacataatt cctgctaaag caatggcact tacagttgta
     3301 gaccttcttt ttgataatgc taaggatgct aaagatatat tagatacctt tactccagtt
     3361 atgactaaag aagaatatct aacattctta gaaaaacacg ataaaacttt ataagtctat
     3421 ttttataata gggtggtatc tactgtaaaa gttataccac tctttgtttt tgtaacagta
     3481 tacttctttt cttttagttt ttagattaaa ctaagatata ttatcctcct taaaactttt
     3541 agagctacgt tgaaatatca gtagaactat gctatattct ttctaattaa tataaatttc
     3601 tattctaatt caaggtggtg aaaaaatgtt taatgcagga aatcgaatta taaatacatg
     3661 gttgtaccct attcaagatg gctttgtctt gattgatact ggatatgaaa atggttttaa
     3721 acatttcaaa aaacgaattt ctaaattcaa cataaaaatc aaagatattc gatacatatt
     3781 tctaactcat gctcatgatg accatgttgg ttttctaaat cagattctag acgaatctcc
     3841 taatacaaag attgttatgc atgataaagc tttagaaatt ctatataaag gtcaaaactc
     3901 ttttattggt ggttgtacca gccgtactgc ctttctcttt tgccaaatta tgaaactatt
     3961 tggaaaaggt gagcatagtt tttctccact taaacaagaa tttgaaaaaa ggtgtattct
     4021 tgtgtctgac aagaatcgta aagaaattga aaaagaacta aatggaaaaa ttatagatac
     4081 accaggacat actgctgatt caatttcact actaattgat gatggtgttt tattttgtgg
     4141 agattctgca atgaatggat ttccaagtac tcacaaaatt accatatttg cagaaagcaa
     4201 actagaattt attcaatctt ggaaaacaat catcaataca aaacctaaaa tgatttatcc
     4261 tggacatgga aaaccatttg aatacagtaa attagaacaa aatctaatct atgtaaataa
     4321 aataaattta tatcctctac ataattcaaa agatattcac agatttttgt agaaaataca
     4381 aagtaaattt ctttgattaa ttaaaaaatc taacacttta ctacgctact tattttaata
     4441 acttaatctt ccactagctt ttcataaaat tttgttttaa aattaatttt aaagtgcata
     4501 tgttatttaa atacattaga taaaattcgt cattaatcta cttaaagcat atttaactaa
     4561 caccactcaa ccagaaaatt cagaaaactg cattgacaca ggaaaaagtt tattttatac
     4621 tttttttagg acatattgtg gacacgtctt aaatcgacaa gcagaattta aattgtaaga
     4681 ttaaccacaa tacttatttt ttaattatat ttttaaacat tagggaggat attatgaatg
     4741 ataacgtagt taagaagaaa aacttttttg acaggacatt aaacagaata gaaactgttg
     4801 gtaataaact accagaccca gttacaatat ttttagggtt atgtgtactt ttacttatac
     4861 tatctagtct agttggttct atgggtatat cagtagttca tcctggtact ggagaaacta
     4921 taaccgctgt aaatttattg actgtagaac agcttcaaat tcttttagga aacatagtta
     4981 gcaatttcca agggtttgct cctttgggtc tagttctagt aactatgata ggtgctggtg
     5041 tatgtgacaa aacaggactt atgacagcaa caatcaaagc atcagtaagc aagattcctg
     5101 aaacaagagt aactcttgtt gtaatgacta taggtatgct tgccaatata gcttcagatg
     5161 caggtacaat attatttcca ccattagctg cacttgtata tcttggtgtt ggtagacatc
     5221 cacttatagg tttattttct ggatatgcag cagtctgtct aggatttgcc gcaaacatta
     5281 tgataagtgt caatgatata cttgctgcaa gttttacagt tccagcagct caaatgattg
     5341 attctggatt tcaagccaat gcaacaatga acttattttt tatgatagca tcaacttttg
     5401 ttctaatact tttggcaaca tgggtaacag aaaaaattgt agctcctaga tttggtaaat
     5461 atgaaggaaa tgcagaacta gatgttgatg gaagtcttag tgatgtagaa aagaaagggc
     5521 ttaaaaaagc tggtataagt atattaatat atgtggctat tatagtagct cttagtgtaa
     5581 tcggtaaaaa accattctta gctgacccag aaacaggaga tttactatca aacaatgctc
     5641 ctcttatgaa aggtatggta cctataatag cactagcatt tttcatacct ggtgttgtat
     5701 acggaaaaac tataggtaaa ataaagaagg ataaggatgt agtctctata atggctagtg
     5761 caatgagtga tatgggtgga tatataatac tagcatttgc tgcttcacaa tttttgcaat
     5821 tattcacaaa tagtaattta ggtctgatac tagctgtaaa gggcggagaa tttttaaaat
     5881 cagcaggaat aaatggacct ttattgttga taggatttat tatattatca tgttttataa
     5941 atttatttat aggtagtgca tctgcaaagt gggctattct tgcacctata tttgtaccaa
     6001 tgtttatgat ggttggatac aatccagcac ttactcagat ggcttatcgt ataggtgatt
     6061 gtataacaaa tccacttagc ccattatttc cgtacttccc tattatacta gcattcacaa
     6121 gaaaatacga taaagatgct ggtatgggta ctgtaattgc taatatgata ccatactcta
     6181 tatcattctt aatagtgtgg actatactat taatattgtt tatggtattt aatattccac
     6241 taggacctgg aatacttcct tcatatagca tgtaatttat ttaaatcttt ctaaaaggag
     6301 aaataattta tgttagataa aaatagactt ataaataatt ttatggatat ggttagaatt
     6361 gatagcccat ctaatcaaga attagaaatg tctaagtggt tggtaaacta cttaaaagaa
     6421 agaaatatag atgccattat agatgatgca ggtaaaaaat atggtggtaa tacaggtaat
     6481 gtcattgcct atataaaagg tgaagaagga agtagaccac tttgtttatg tgcacacatg
     6541 gaccaagttc aaccttgttt aggtgtaaaa ccaatactag atggtaatgt agttagaagt
     6601 gatggaacta ctacacttgg tgcagatgat aaagctggaa tagctgctat acttgaagct
     6661 ttagaacatg ttattacaga aaaaatacca catagagata tttatctttg ttttacaatc
     6721 tgtgaggaag ctggtatgca tggtgtcaaa aactttaatc ctgacaactt gccttgtaaa
     6781 gatatggtga ttttagattc tggtggagct attggttcga tagcatacaa agctcctgct
     6841 caacaatcta taaaaatctc ttttcatgga aagaaagcac atgctggtat agaacctgaa
     6901 aaagggttaa atgctatatt agtagcctct catgcaataa gcaacatgca cataggcaga
     6961 atagattcat tgactacttc aaatataggt aaaatagaag gtggtggagc tacaaatata
     7021 gtaactgata aggttacatt gactgctgaa attaggtctc atatacctga aactttagag
     7081 tatgagctta atcatatgga aaaatgttgt aaggatgctg catctaaatt taatactact
     7141 tatacttttg aacataatat gtcttaccct agttttgaac ttagtagaga tagtcacgtt
     7201 ttcaagttaa gtgaagaagc aataagacaa gttggtgttg ttccaaatcc aatggtaatt
     7261 ggtggtggaa gtgacgcaaa tatattagct aatcttggat ataattgtgc tatattaagt
     7321 ctaggtatgt atgatgtaca cacagttaat gaatatgtaa atatagacga attatatgat
     7381 actgccaaaa tagtttatca tatgattaaa ttataaatat cataatagaa ctctttaaat
     7441 tataaaaaca aaaacctatg tatcttcaac tttataagtt atatattaaa gttgttttac
     7501 ataggtttta gtatttttat aataatttgt tctaattttt ttcataataa gctttaatac
     7561 tttatatagt aatttgttgt agaattttat acaatataat gatttataca gttttataaa
     7621 atatcttaaa acagtatttc agtaatattt tttggtcttc ctccaccaat actagtctct
     7681 tttgcacata ttcgacctaa acctgcattt actattttat ttaatatacg tcttgcactt
     7741 ctttcactta catttagata ctctgctaac tcttttgaat cataaatctt actttttcta
     7801 ttctcactta tagcaataat ttttgcaact gactcacaac tcatcccagt ctttttagat
     7861 atttctatta ccttttcatc agatagcatc aaagaataat ttaattcatt ttcggaagct
     7921 aaaggtcctc ttatgttttc atcttcatct accaaatata taccaatttc ttttgaatct
     7981 atggagtgtc ttaatgcttt atgtgcatta ttttcagcct gatacgcagt tactccagta
     8041 ccaattccta tactaagaga aaagcccatg tcttttatct ctctctttag attgaatagc
     8101 ttatcataat tatactcatt atcagctacc cctttatgaa caaatacaac ataatcattt
     8161 cttccaagta aaaataagga accttgaata cttcttacat agtttactac aagcttatcc
     8221 atatctgatt tttttatcat gtcagaataa tagttatcta tcttctcttt ataatctatt
     8281 aaactcaata tttcaacagc aatttgagaa aatcttgcct tacttagagc atattcactc
     8341 tttaccttgt cataactttc tttgattaat tgtatagtag cttgtaaacg aaatacagga
     8401 tagcctcttt cttttaattc attatatact gcaccaaaac cagttaacat tatatccgtc
     8461 ttattttctt caaataattt tatatgccat tctacaagtt cagactctcc tacttccaaa
     8521 gaaaacggat tacaaaatac actcgttgct ttaatatcaa attctttaag tgcatcttcc
     8581 acaacatatc tatcaactac atctatactg aatttatcta attttatatt tgcacttttt
     8641 attgcccaaa atgccttcat tatactcgtc ccacttctcg gtacaaatga atgtggctta
     8701 cttatctcat acttagattt tataaattca taaactgcac atcctgtaaa tataatagca
     8761 tcacattcgt cttcacattt agaaataact tctattgtat ctactacttt ttctcttaca
     8821 tatattttag tctttaaatc actgtctatc tgttttaaat catcctttat cttaaaccca
     8881 gagtctgaag gacctataat acccactatc ataaacttcg ctcctaatcc ataaatatta
     8941 tactttttaa aaattatatc ctcactattt tctacttcta tttaattatt ttgaactact
     9001 ccatcctacc tacatttaga atggaataat tagcttattt ttgataaagt aacttctcaa
     9061 aatcagcact tggaataggc ttacaataat aataaccttg aattaccaca caatctaaac
     9121 tcactaaaaa ttcagcttgt tcttttgtct ctacaccttc tgccactaca tccatatcta
     9181 aatcttttgc catggctata gtgtgcttta aaactatttt ttctctgtct gtgattcctt
     9241 cctcattaaa gaaaccacaa tctatcttta atgtatcaat attaatattt tttaacatat
     9301 ttaatgaaga atatgctgaa ccaaagtcat ccatatttaa aacaatacca tccattctaa
     9361 ggtcggctat tatcttagta aataatttta tatttttaat aaataaactt tctgtaagct
     9421 ccaattctaa aaaagatttt ggtatactat atttatttat taaacttaaa acaatttctt
     9481 taaaatgtgg attatgcaaa tgtaatcttg atacatttac agagatagga actggctctt
     9541 cacctaaatc tatccatttt ctaatcaaag aacatacttg ttcccataca tacatatcta
     9601 atctgataat aaacccattc ttctcaaata gtgaaataaa tttaattgga ggtattatac
     9661 ctttttctgg atgaacccat ctaaccaatg cttctgcacc aacaatttta tttgcattaa
     9721 gattatactt aggttgtaaa tatacatgga attgcccatt ttcaagtgcg tattccattt
     9781 ccctttccat ctgtttttct tcaagtgcat catttcttat agtatcatca taaaatatat
     9841 agttgttgat actttgtttc tttacttttt tgtgagcata tcctgccatt tcacacgcat
     9901 ttgtaattgg aatatgatta tccaaaattc tataaacccc aaaacatggt actaacatat
     9961 attcaaattt ttttctattt aagctatttt taatcttata aattacctta tgaatatctc
    10021 tatcagagta actctcataa aaaatgcaaa atacatctgc atacatacga caacatatac
    10081 cattagaacc aatgtttttt tgaatcaact ctgcaacata tattaaagct ttatctcctc
    10141 ctctaactcc ataaatgtca ttaattacct tgaacttatc tatatccatc attataattg
    10201 cataacgctt gtcaggatat cttttaagca ttaaacttat ttgttcacaa aaactttcat
    10261 aattgtatag tcctgttaat gtatcttttt ggtttttatg tagttgcata agataatcta
    10321 tattttttat agcaactaaa atatgtgttt gtttctcacc taacttattt ttactactaa
    10381 tctttaacat ataaattaat gcccaatagt actttttatc tattcctaaa cgtctatact
    10441 caaaatttag ttctaaatcg tcttgcttgc tattattaag actatcaaga gattttagaa
    10501 ggtggttatc attaaataat attatatcat caggatgaat taaatgtttt tttatgtatg
    10561 aaaaagtttt ttcaagattt tcctttatag gaaaactaaa aatattgctc tctgattgat
    10621 aaattggagt aattaaattc gtatcaatgc aaatagataa aattatatca tatgtattat
    10681 aagctaattt ttcataagct ttagaatacc cttttatcat taaatcatca aaataaacct
    10741 tatcaactaa ctctttatgt ttaaataaaa tattattcgt cgaatcagct aagtcactaa
    10801 ttactttcat ttcattattt ctaagtttgt tcttattata atacctcttc ttatcttggt
    10861 acattctctc atcagcaact ttaattagct tatgtatatc aatattatcg tcactccaaa
    10921 tactgcccac tgctacacta tatatcatct catccttaaa ttcttcactt aaccaactca
    10981 ctaattcttc aaatagttgt tttgatatat cttcacataa tacaacaaac tcatctcctc
    11041 caatacggta aacattataa gaatgaaagt atttttttat tattacacat gctgacacaa
    11101 tagcagaatc gccattagca tgtccaaagt tatcattaat atcttttaac ccatttatat
    11161 ctacaaatac aactcctatg gatttaactt ttcctttttg aaaattatct atatacttaa
    11221 tatatttatt tctattatat gcaccagtca agaagtcata gtagctcata taatttaatt
    11281 tattttctac ttttcttttt ttcatctcag ttaataaaaa ataagatagg gatgtcaaaa
    11341 gagaggtatc tccaacagct ttatgtggat tatcaactcc aataaaccct actactttat
    11401 catcttgttt tagtgaagat gtcattaaac tttcaatttt ttgaggtttt aaaatttcat
    11461 attctattgg ctgttcttct tttatatttt ctatatcatc aattattaca aaaccttttt
    11521 gttcgaataa taaaaaccaa ttctttaatt cattaatatc aagatttgtt agtgcctgtt
    11581 tttgttcatc aacaccttca ttgcaccatt catatgtatt agttactttt gttctatctt
    11641 ctgatacttc aaaaacatat gctctatcag ctttatgaaa tttaccaata ttggttaata
    11701 caagatttac agcatcagaa aaattagatt ctgttataag atgtttaata catccaacta
    11761 ataactcctt tatctctaat ttttctgcta ttgacttact tatatcttcc ttttctgtaa
    11821 tatcaagagc tatttctaat cgtgcatgtt taccctccca tttaattaac ttgtccttta
    11881 atataaaatg tctatttgtt cgagtattcg tattttccca tatgtaatat tcatcttctt
    11941 ttaaaataga gtttgtacaa aattcgcagg gagaatcttt cccctgtaat gctttataac
    12001 attttaaatg ggatatatca ttaagtccca ttgccttttt cccaatttca ttaatatata
    12061 aaagttcata tgtatctaaa gaagaaacat atacaatttc atccaactca tctattaaat
    12121 ttattacatc catttatata tatctccttt tattcatttt ccagattgaa tttttaaagc
    12181 ttttaaaatt ttgctatata tttggcaatg atattatact tctttatgtt ttaaaatagt
    12241 accttaatga ggttctattt tttagtaaat agaattatta ttgtgtcaat cgtacaatag
    12301 agttttgtaa tacctaattt aatatattta taattaatta tctcattatg tgtttataat
    12361 taattctcat ataaatgaca aatctccacc tcaattaagt attccaatca tatatgaaga
    12421 taatacttca ttcatttaaa aatataaaac tattatatat taaaatttct tcaataataa
    12481 attatctaga ttgttacttt gatatattat ataatatcac aaaggctgat ataaaaagac
    12541 aaaaagggca atttttttat atcaaaaaaa atgttaaatt gatattatcc atatagatgc
    12601 tatatttaac aattctactt acttccctta cacttattag catatagtta ttaagagttt
    12661 gttgcaaaac aacacttagc acactttaaa aagtgtggtc taataagtaa tcaacgaaga
    12721 agacataata aagcataaaa tatgatatac ttttccacgc catcaaaatt gaggatttta
    12781 ttattaatat atgctaaaat atgcttaata aattaaattt taatgggaga atagttatga
    12841 aaatatttag tttcttgttg tttgtgatag gaatatgttt atgtattgct ggatttatag
    12901 gacattaccc agtatttgtt ggtgcaacat tgagtttttt tgcaactaca atgatagctg
    12961 taagacaagt caaaactaag aaaaaatgaa ataggcaaat cctaacttta caagttaata
    13021 ttacacaagt aattagtcta aaattggata ctttttctat tacagaaata catcatccac
    13081 tttgtatttt cttaaaaaaa taaaatagct atgtaaattc aagattagat agattaactc
    13141 tctatccatt tcattgtaaa atatacatag ctatttgtat tcgatttaaa atacttagat
    13201 tttcttacat aacaaataat ttctatctga ttattactca tattcattta gtaaccactc
    13261 agcacctaat catttagtat ctattcatcc gccatacggt aacctacccc aacctcagtc
    13321 aaaatatatt ctggctgagc aggattcttt tcaattttcc ttcttatact tgccataaaa
    13381 actctaagcg actgattttc actttcatag taatttcccc aaactttatc tattataaac
    13441 ttatgggtta agactcttcc tgaatactta gacatcaact caataatctt atattcgatt
    13501 ggagttaaat gtatttcttc accattaatt gacacaatat gattttcata atctatcttt
    13561 aggtttttaa cttcaaaaga ctttggagca tcattattta tattatcctg ttgagcttta
    13621 tttctaagag ccacacgtac tctagccaaa agctctgtta cactaaaagg tttagttaaa
    13681 taatcgtctg ctcctccatc taaagcttcc accttatccc tctcatgctc tctcgctgaa
    13741 acaacaatta ttttattagt ctttgcacat gccctaactc gtcctattac ctcaatccca
    13801 tcaatatctg gtagtcctaa atccaaaatt atcaaatctg ggtcaagaga atgtataagt
    13861 gatatagctg ttcctccatt atctgtctct acacacctat aattttgagt ttcaagagat
    13921 acttttataa atttacaaat tggcttatca tcttctacaa ttagaactaa tggctttatt
    13981 tccacttgtc tttcccctcc tcatcataca taggtatgct aaatctaaat gtagctcctc
    14041 cagaaggatt attaaaggcg acaatttctc caccatgagc ttctactata gatttacata
    14101 tctccaatcc aagaccaata cctcttcttt caagatttct agacttattc ttagtataaa
    14161 acctattaaa aatattcccg atatcttcat ttggtattcc ttttccatta tctgcaactt
    14221 caaatagtac ttgatttgac tcttttttta cagttagttc tatcttagaa tttttaggtg
    14281 tatgccttat agcattatca attagattta ctaacacttg ttctattaat aatacatcca
    14341 catgaacgat tattatctca tctggaatat ttgtttttat gtctctacta ttggcaaact
    14401 ttttgactct taatatagat tcagctatta tttcatcaac aacttctggt cgtttttcaa
    14461 tatccaattt tccttcatct attctggtca tactaagtat attctcaaca gaatgagtta
    14521 gccaactcgt atcttcatat atatttttca ataattctac tctagtttct ttatctatca
    14581 catcatcatt ttcaagtatt gttgaagatg aacctaatat acttgtaagt ggagttctta
    14641 aatcatgaga aattgaccta agcaagtttc ctcttaatct ctctctctct gcctcaagat
    14701 ttgctttttt atttttctca aataaatttt ctctatcaat tgccaacgca acctgtgttg
    14761 aaactgcttc taatagtatc ttttcatttt ctgtaataat atctatctta aaacacgcaa
    14821 cacctataac accaagaaca tttgattctt gaccttttat agggaaataa tatgcactgc
    14881 tgtttttaca atattttgtc ccaattccaa ctgggttacc tgtcctaaaa gcttctttta
    14941 tagcttcctt ttctaatact gaatggaata tattctcact tccatcattg ttacaaatat
    15001 aaatacttgg cttacctaga ttattattct catctgcaat agtcactatt acagttctat
    15061 ttaatatatt tactaaatta gacccacaaa attcaataat ttgattttta ttttttgctt
    15121 taagcaacgt tttgttattc tcatagagca atcttatcat tttttctctc ttatgagaaa
    15181 gtctcacttc tctttttatc ctagaagtta aagtacttgt tataattgct gccattagca
    15241 taatacaaaa ggtcatagga taatcttttc tataagctaa aaaagtatat aatggatgcg
    15301 taaagaaaaa attaaatgat agcactccta ttactgaaga aagtattcca aaaaaatatc
    15361 cataggttat acttgtagca aatagtacac ctaatatgta tactagtata atattagatt
    15421 cattaaaacc taccttttca aaaactactg atattccagt agcaattgtc ataaccaata
    15481 tagtttttat gaagtcctta ataattatct ttttactgag atagccatct tcatcataat
    15541 catactcttt taagtcttca tgttgtagtc gttccttttt catttactac aattcctcct
    15601 tattgttact gtttaaattg gctctatttt atataataca attttatcat aataaattca
    15661 atcaatacat ttaattaatg tacttaaatt actaaaaggt gctgtcttaa aatgaaaata
    15721 aatctctatt tcaaaacagc acctatatat ttaaattact aatttagttt ttacatactt
    15781 aaatcaatag ttttattcaa tttcataaat tataatactt caattataaa acatttctat
    15841 ccaacaagca taaatataaa gtgggcacat atacctgcac ataaaccacc tatagtatgc
    15901 gaaagtatcg ctttaccagc caatggtctt gcatctaaag catccatcat acctatgtgt
    15961 gtacttaaat atccactcca acacataccc attgctgtga atactgctat atcattagga
    16021 gttatagcgc ctgattttat aaactctggt actaaagata ttgctgctcc aacagctcct
    16081 aatgcagtta cagggaatgc tattgcctct ggtgatgtga atccaaataa tggttctatt
    16141 atgaagctaa tcttatcacc aatagcaggt aataatttta taccttcata tgcagctcct
    16201 gtgtaaacag cttgacctgt agcagggtct gtagatggtc caaaagttaa taacataact
    16261 aatgtacaaa ctactaaaac tcctggtatt atagccatac ccatttcaac acctaactta
    16321 ccaccttcaa gtatagcatc caatgttctt tggaatacat taccatctct tatttctcta
    16381 aactcttcaa gttttgcacc tttatcattt atttgctttt cagtatcatt tttagggtca
    16441 taattataat actttttagt aaaagtcaac ataattctaa cactaataat actacctatt
    16501 attgccgcaa cattacctat tatagctggt agtacatatt ctttaccttg agctatcata
    16561 aaagttgtta caataagtcc cataccaaag gctgttccta aattacataa agcaggtact
    16621 tgatacttct taaaatattg tgtaaatgtt ttgtctttag caaatggtat aatagctgga
    16681 ttatcagata aatatgttgc aactactcct gctatactag caccaggtaa gccccatata
    16741 ggtctcataa gacccttaaa tatcttatta actaaagata ttactccaaa ctctgaaagc
    16801 aatgcactaa gtgcacctgc aagaactgcc atagccatta ttaaaaatac tgtgtctaat
    16861 aaaagcgcat gtgctgtact cattattact ttaaacatca ttcctgcacc catgatgctt
    16921 cctacatatc caaatcctac cgccaatagt acaataaata cgaaggtttc catacttact
    16981 gccttgactc ttctcttatc cgacagcttt tccatcttga aatcttcccc cttttaattt
    17041 taaattaagg ttcctaacat tggtacaaat tttttggtac aaactgagtt ctaaaactta
    17101 cactcgtaat gcaagttgtc agttttttga aataaaaaaa aattacgttt atagaataag
    17161 aatatcctct ttaatttgga tactcttatt ctattttatg ttattatatt atcatccttt
    17221 tgtttaaaag tcaatttttt ctatttttgt tgtttaattt tatttatact ctttttatat
    17281 ttttcatttt cttttatctt tgtaagtact ccatataagt tgacttttct aaatacagta
    17341 gttataaata ccaatcctaa tgcaattgaa cttgcacacg ataatgtact caccccatat
    17401 tctacagctt ttatataatt attggtcaaa acagaataca tagtattata tattccataa
    17461 ccaggtacta atattattaa acagcaaaca cttaatgtag ttgctggagt catataaatt
    17521 cttgcacata actcacaata tatcgcaaaa caaactgtag ctataaaaaa acataagttt
    17581 tctgttactc ccatatttaa aagaaattta tatgaaaacc aagctatact tccacctatt
    17641 cctgctagta ttaagttttt tcctttcata ttaaatagca ctccaaagct taaggcagta
    17701 aaaaaagctg ctattacttc tataaacaaa tgcacttata tcccccctaa cttgaagtac
    17761 aatccaagta ccaagaacat tcctactgct atagatacac ctacaaaaaa tacttctgct
    17821 aattttgcaa gaccagaaat caactgtcca tctaacaaat ctcttaatgc attagtcaaa
    17881 gcaagcccgg gaactaagag cattattgct cctgctatta aatggtctaa cgtctttatg
    17941 aatccgagct ttaaaattaa aattgaacaa gaagctataa taactgctcc aattgcattt
    18001 acaaaaaagt cattaaggga agatttactt aaatacataa taacaaactt agtcagaatc
    18061 ccaacagtaa atgcagctat aaattcttcc acatttcctc caaataatat cgaaaaagtt
    18121 gctgctgcaa tacctgcaaa aaatattgtt attaaatccg agtaatagtt atcttcactt
    18181 atttcatcta aaattttctc acataattca atatctaaat tatttatact tattgctctt
    18241 gataatgagt taacttcatg aaccaagttt aggtctactc ttcttgagct tattctttta
    18301 attgctgaat gtaatttccc atctacaaat acagatgcca ttacagctgt tggagttgca
    18361 aatacatcta cgtggtctat tccaaaagat tgacatattc tagctatcgt ttcttcaact
    18421 ctataggttt ctcctccact ttgcaacata gctttacctg catttgagga aaagtttaaa
    18481 attctatcta tatccacaaa acatatctcc cattctttta tagtattatt catattttaa
    18541 tacaagatat tatttattta aactatttta aataattcat atccaatatt tacattttat
    18601 gaaaaaactt gttttttatg cttgtcaaaa tcaaatttta agcttgttta caccataaaa
    18661 tggctgaatt aatatttgac aaacactttc aaccatttat ataaccttct aaattgtata
    18721 actttttact acaaataaaa ttatatctct tttaattctt tctcttgagt atttagctta
    18781 tagtaacttc atatttatat atgtacaata taaaacatta tttttatgat acaaaatata
    18841 atttgtaaat gtatatatgt attaactgtg tatatataaa ttattcttaa ccttatcagt
    18901 tttttcacat atcttcatct ataccgacca tatattaata aatgatatta catagactta
    18961 agtatattaa aaaacttaaa tttagttatt taacaacata atactctaat ttaatctata
    19021 aaaatccata cctaatataa tgcaactctt attttaacac catctattac acaaaacaac
    19081 atattaaaaa gtaaaataca aaatatccac tataaacctt attttaatac tgaatatata
    19141 ttataatata tttaatgtag cttaaatata gtttaaacat aaagaaagga aacggtatat
    19201 gctaagaaaa gataaagttc tattatctct acataaatta tgtgaaaata tgactttaaa
    19261 agaccttcaa tcagataaaa caggattcac tacaatagaa attgctaacc attcatctct
    19321 tgatagaagt aataccagta aagaattaaa taacctatac aatgaaaaaa aagttctgaa
    19381 aatatctggt aagccaattt tatttctaca tgctagtatt atagaaaatt taattggccg
    19441 tactttgaac actgatgaat tttctataaa taattgtaat gagctactta aatcaagtaa
    19501 aaatgactca gaagatattt tttcaacatt acttggacat gattctagtc ttaaactacc
    19561 tatagaaaaa gctaaatctg ctatactcta tcctccaaaa ggtcttaata cattactcat
    19621 aggacctact ggtgttggaa aaagtacatt tgccgaaaca atgtacaaat atgctgtaga
    19681 aagtaaaatc ttttcttctg aaagcaaatt cgtagtattt aactgtgctg aatatgcaga
    19741 aaatgctaac ttattattaa gtaatttatt tggttatgtc aaaggttctt ttactggtgc
    19801 taataaggat aaattcggca tagttgcaca ggctgatgga ggcatattat tcttagatga
    19861 aatacacaga ttgccaccag aaggtcaaga gatgcttttt cttttgatgg acaaaggcat
    19921 atacagacga ttaggagaat ctgacattgt gcacaaagct aatgtcttta ttgtgtgtgc
    19981 cacaacagaa gatatacatt cttctctgct tgggactttt ttaagaagaa tccctgttac
    20041 aatcaaccta cctgctttac aggataggtc tttaaaagaa agattatctc ttattaaata
    20101 cttctttatt atagaatcaa aatacaccaa tgcaactata aaagttcaca aagatgtaat
    20161 taaatcatta ctcctttatg attgttttgg taatataggt cagcttaaat ctgacataca
    20221 acttatgagt gcaagagcct ttttaaatta caaaactgga cttaaggata atatagaaat
    20281 agatttatcc cttgttcctg attacatcta tattggtctt ttaaaattga atgaaaatcg
    20341 tagtaatcta aataaattat cagaacttga ttatatgctt ttttatgaat ttaatggtaa
    20401 taacttagaa gttgaatata caaaagaact atctaaatac aatatagata catcaaacaa
    20461 tggatttaaa tactctacag agattcctta tctggaaaat gatataagga gtatgtttat
    20521 aaattacatg gaaaagtact ctacaaaatt actttcgata tcttcagtaa ctcattctga
    20581 ttatacaagt aatgagattt ttaaagtaat caatccaaag atttactatg ctgttgaaca
    20641 ttctttaaaa gaggctgaaa aaatatcgag aaacaaatac acaaaacaaa cttatattgc
    20701 tctttcaatg catataagtg cacttataga aaatataaat caagacacat ataatcctaa
    20761 gtacaattta tataatgata aaattttctt agataaagat ttaaatatag ctaaaatagt
    20821 tttaagtata attgaaaatg acttacaaac atctttacct aaagatgaag taaaatttat
    20881 atccatgttt ctaaatagca tgtatcttga accaaacaat caatctgaaa gtataggagt
    20941 cataatactt gctcatggaa attcaacagc aagcagtatg tgtgatgtag caaattcatt
    21001 gcttggtaca aaccattgta atgcaattga catgcctctt gatgtaaaag taagtaccat
    21061 acttgataaa actatagagt tggtaaaaga atgtgacgaa ggtaagggtg tacttctttt
    21121 aacagatatg ggctctctta tagcttttgg agaacttatt tcagaaaaaa caaaaatcaa
    21181 aactcgctca attgaaatgg tatctactcc aatagtttta gaagcagtaa gaaaaagtac
    21241 actaccagaa atgactttgg atgaattagc taattcctta agctctttaa atccatatat
    21301 tggacgagca gcaatcgatt caacagaaat aaactatcct gaaaagtcaa gagagtatgt
    21361 aataataact acttgtataa caggatatgg ttcagctatg aaagtagcag actttataaa
    21421 ttcttcactt aaaaatatta gtaaatacaa tattaattta gttcctcata atatagaaag
    21481 ttttaaaatg tataagaata aatttagtaa tactaaaatt ctggcagttg ttggaagtgt
    21541 agattttaat gtagccaaca ccccttttat acacatagaa gaactactaa atggatatgg
    21601 cctagatatg ctaaacaaaa taatagaagg tacattcaat gccaatagta ttacaaatat
    21661 aaaagaaaca aatctatcat acaacagttt aataataaac tttatgaccc aaaacttaga
    21721 gcttttggac tctgttaaat tattcaacta tgtcaattct tccttattta caataataga
    21781 attaatagat gaaaacttaa agagcaaatt taagctagga tatatactac attgctcttt
    21841 tatgatagaa agatgtttta aaaatacaac ttttccatat aataacatta ctgaattaat
    21901 tagtaaaaat catgaactat atagtttaat acgtgaagcc tttaagccaa cagaagctta
    21961 ttttaatatt ttgataccag acgaagaaat tgcttatata atagacatga ttaatgagta
    22021 tctaaataaa taaaatttat agcacttatt ttgtgcatat taattaatat atgaaatgga
    22081 ggacgagatt ttgaaaggaa aaataaaaca gttaacaata cttgcattaa tttttatatt
    22141 tataactcct gtatttgcat ttgcagatac tccaccagta ccaaattctt caagagcagc
    22201 actacttata gaccaggaaa ctaaaagaat attatttgaa aaaaacattg atgaaaaaat
    22261 gccattagcg agtttaagta aaatgatgac ctttttattg gcaatagaag cagttgataa
    22321 aaatcaagtt aaagagactg atatggtgaa aatagacaag tctacagctt cagtaggagg
    22381 ttctacttgt aaacttaaag atggtgatga aatatctcta ggagagctta tgcagggtct
    22441 aatgctagta tctggaaatg atgctgctat agccatagct aaacatattg gtaaaactga
    22501 aaagaatttt gtaaatatga tgaacaagaa agcagaagaa ataggaatga ttgatacgta
    22561 ttattttaat ccaaatgggc ttcctatata tactgaccca gaacataaag aacctcctat
    22621 tgaaaatatg tcaactgctc acgatatagt tacacttgga aagtatatgt acgaccatta
    22681 tgaaaatcaa gttacaagaa taaccactat gcaagtatat aatgatacta aaaaggattt
    22741 tacacattat aacacaaatc ctctgcttgt ttcagtacct ggtgttgatg gaataaagac
    22801 aggatataca gataatgctg gatattgcct tgcattttct atgatggtac ctaaagatgc
    22861 taaaaacgaa agaaatcata gattgatagg tgttgtactt ggtgatggta acaagaaaaa
    22921 tagaatttct tcttccgcta ctttattgaa atatggtaaa gataatttcc attctaaaaa
    22981 gatagcacat aagggtgata ttatagagac tccttgtgtt gatggtattg atgattttaa
    23041 gataacagtt aaggttgata aagatttgta tggtgttgtt tcagataacg aaaatatcaa
    23101 tcctaaggta gtgtttaaaa atatgaatta tcctatccat aagggagata ttgttggtgt
    23161 tgcaaagtat tataatgatt ctggtaaatt tgttggaagt gttgatgtaa aaagtgaaag
    23221 taatatagga tgtattcctt tgaaggataa gattaagatt aaggttgcta agataaataa
    23281 aaaacttgag attaaaaatt ctgtttgttt taaagcatag taaagcatat tattaaaagg
    23341 gtatgttaaa tttataaaga ctccactttg tggagtcttt ttgtttttta caaaaaatta
    23401 aaatagtggc aacaattgag gatgtgaggg agagttgcca ctattttgta tagggtatta
    23461 tattatgttt ttaagctagt tttactatct tctatgttta tataataact cttgtgtgtg
    23521 aatttaattg ataattaata tgaaaattat gtgaagtttt gatttatttg taatatattc
    23581 tactactatt ataatttttc tactggatat actaatcatt tgtttaacat tatctgagat
    23641 tgatttgcaa acttttatat aactaaatta gttatataac ttatagattc cattaaatac
    23701 cctaataatc atatatgtac atacaaagtc atgcttatgc aaaatctgca gtttcaacta
    23761 acttattata taaaccatct ttatgtagaa gttcagcatc atttccagat tctattactc
    23821 tacctttatc taatacatat atattatcag cactcttaat tgttgaaagt ctatgagcta
    23881 ttataataac tatcttatct tgtatgtact ctttcaagtt gttcaatatc tctttttgtg
    23941 aaatattatc tagagctgaa gttgcttcgt ccagaataag taccttttta ttacttacta
    24001 aagctctagc tattgatata cgttgttttt gacctcctga tattttgaca cctttttctc
    24061 ctactacttc gtccaatccc ttatctagat tttttataaa atcatctaaa caagtaactt
    24121 ctaatatctc atctaattct ttatcactta ttttattatt taatactata ttatttttta
    24181 ttgtgtcatc aaatacaaat tgatcttgag ttactatatc aatattattt cttagtgatt
    24241 ttaaattaat atcctttata ttaacaccat ctattaatat atcaccttca tttatatccc
    24301 aaagtcggta tattagattt gttattgttg atttgccaca tccacttcca ccaacaattc
    24361 ctgttacttc ccctttctca aattgtaaat ttatatcatt taaaacaagg tttaaatcct
    24421 caccatatct aaaagataca tttttaaaat ctattttctt aatttcactg ttatctattc
    24481 tatatccatt attatcaact ttaatatcta tcttttcatc tattactgaa aatactctat
    24541 tgatagacac ttttgattgt gctattctag tattcgccct tactatagct atacatggtc
    24601 caattaacat tcctgtatat tgttgaaatg ctattaactc ccccatcgtc atcttattat
    24661 ttattatttt atatccccca attccatata ttaatattgt tatcaatcct gttagtattt
    24721 gagatattgc tatattacta ctcataatga tgttcaaatt caaatctttt tttatcaaat
    24781 ctctctctct ctttaaatac ttattaaaga aattcttttt tgaatttaat ataacaatat
    24841 ccataatatt agatacgtac tcttgaatca aatttgataa actgcctgaa tcacttctta
    24901 tttcagaaat tttcttagat ataagttttg tcattttatt ttgagaaaat gttaatatca
    24961 actgtaaaaa taaaactact aaaaataaat caaactgcaa attaattaag aaaattaacg
    25021 atattatagc tgtaaacaca tttacaataa tatcaaatat aatctctgct ccaaagtttt
    25081 ctatcataaa tatatcactt tccataatgg ataaaatatt acctgttttc ttacttgaat
    25141 aatatctacc agaaagtttt gatatatggt taagcaactt tacttttaga tttatagtaa
    25201 ctttattttt tattgaagta tataaatatg ataatataac atcaaatgta gctgataata
    25261 tccttataaa aatatatatc aatattaaat ttataagcag aaaaatattt ttatttccta
    25321 ttccatcatc tattatacat ctaattagtt gaggtattac aatatttacg ccagcaatta
    25381 taaaaaccat tataaatgat actatcaact tagtcttatt cttatatact attatattta
    25441 gtattctaaa taaattatta ttaatagttt ttttcatcta tttttccatc ttttatagtt
    25501 ataattctat cagctgtctt tgcaatatta tcattatgag ttatcataac tagtgtttgt
    25561 ttgtactctt taacacacca ttcaagcata ttcataactt catttgtagt cttactatct
    25621 aagttgccag taggttcatc tgcaaatatt actgacggtc tattggctaa agctctagct
    25681 attgcaactc tttgttgttg acctcctgat aattcattcg gatatttctt tatttgtttt
    25741 tcaatcccca acttattaat taatctcata acatattctt tatcttcttt tttcccatca
    25801 agcaacacag gaagtactat attatcatat acatttataa ctggtattaa attgtaactt
    25861 tgaaatatga agccaaattc ctgtcttctt atttcagaca gcttatcatc atttaatgta
    25921 tataaatcta catcatctaa gtacacattc cctaaagttg gcttgtctaa gcctgcaaca
    25981 cagtgaagta gtgtactttt accagaacca cttgcaccta caatagctgt aaatttatgt
    26041 ggctctatat ctaaatcaat accatcaaga gctctaactt cattctcata ttttccatat
    26101 atttttttta aatcttttac cttaagtatt ttcataacgt atctccattc ccatttaaaa
    26161 aacatatatt tttaaattaa attttcgtaa ataagatcta ctgccatatc taaattctct
    26221 aattgatata agtatacttc tttgtagtca atactaatat taaactcttt atttaaaata
    26281 gttaaaaaat tatatgcatt ataatttcca atacatgtaa aattgttaaa taaagaatat
    26341 tcacttacaa attcaaagtc tatttttatt ttagaaaagt ttctatttat cacatttatt
    26401 attttccttg ctatatccaa tcttatcaaa ttagatttat aacttggagt gttcaagttt
    26461 tctattttta aatcttcttt acttttgctt ttttgaataa gtatttcttc caattcatta
    26521 aacttaatat atggattgtt ttttaatata tttgcaacaa tgccagttgc cactgcacaa
    26581 gccttactat ttttaccaaa atgagttact ttatctttaa atttaataaa attatctttt
    26641 gaatttgcat acatttgaat cttattttct ggttcgtata tatattgatt atttttatat
    26701 atattttcat tacctactac accaataaca ctttcaaata tagtaggaat actttcttta
    26761 tcttcatatt tattatgttt tgaacaaata ataaatctac cttgactatt taaaatatta
    26821 caaacctttt ctaattcttt ttcatacata ctactaatag atgcagctga aatgtttatt
    26881 atctgtatat ccgacatagt caacttgctc agtgtactaa gaagatttaa agaacttgtt
    26941 tttccagaat cattaaatat attaatagga taaatttggg tatttttact tatatttaat
    27001 atggttttcg atacaaaagt tccatgtcca tttatgtcat ttatttcctt cccccccaaa
    27061 tctttcaatt gaaaatttga atcataaaca taatttccat taatatcatc atcatttaca
    27121 tctaatcctg tgtctaagac tgctattctt actttagtca attaataatc acctctaaaa
    27181 taaattacct tgaatataaa actaatcctt accataatat aggttccaag atgtttttca
    27241 tttttttaca atttgcatca aacatttttt tgttattttt taaagtatat attttcgatg
    27301 gacaagttgt acaaaataaa tttactttac attctttaca actctcaata tttactggtt
    27361 ttaatttatc aaatatatta aatatatcca tttctctatt aagaatcctc tctaatatgt
    27421 tttcattaaa ttctaatata ttgaatatct ttaaatcctt atactctaag tttggacacg
    27481 gatatacatc tcctttatga tctatactta tctgattaac acctgcttta cacatatttg
    27541 aacataaact actttcatcc acataatcat ctttgcaaat gtaatcaata tcaagtttat
    27601 cattaagata tttgctatag ttctcattac ctctaccaat attcataaaa tttcttatta
    27661 taggcgttgt acctaaatct tcatttaatt tattgaattt ctctatgtct ttctcattat
    27721 tctttcctac caccatagac aaacctacgt tctcgaattt ttttagtttt ataagtctaa
    27781 tcacatttaa tactttacag aatactcctt tacctcttac ttcactacaa cttaattcat
    27841 cataaccatc taaactaatt tctattgcat ataaaccatt aattatatca tcaatctgtt
    27901 tttctttaat taaagttgca tttgtagaca gaattatttt acctttaaat ttttctttta
    27961 tataatccaa cagctctaag aaatcatttc tcatcaatgg ctctccacct gtaatggtta
    28021 atatccttgg atttaattta actatattat ctattacttt tcttacttga gatgtatcta
    28081 aataatcgtt attatctatt ttagaatcta cacagcaata atcacaactt agattacatc
    28141 tattagttgg agaaaatgaa attttgttta ttctctctag tctaaattca cttagaatag
    28201 aatcacttag aagtcctata tgctctaact tatctataac tcgttcataa tattttttat
    28261 cttcattttc ttggaataca tcatacaaat taccaagttg taatgcatta tctactgaat
    28321 actttagaac ttcataacat tctattggaa ttttaaccca tcttccattt actttattac
    28381 taagaataac ttgattatta tttattattt tttcacatat acaatctaaa aaatatttgt
    28441 ttgagctatt catttatttt atttccttcc tatatattta aattagaaat ttcattaatt
    28501 ttcttttata ccacttacta tactaagttt atttatcatt ttattagaaa aataaactgc
    28561 aatgacacaa acaaaaacag atatagatcc aaatattaga atttcatata ttggaatttc
    28621 aaatttaata gagttattta taccatatac ctgttgatta agtttgttag tttcagaaac
    28681 tattttataa taattgaaac tagatataat tccagctaca atcatactta ataccccata
    28741 tatcatattt tcttttatta acattctttt tacatttttt ttggacatcc ctattgctct
    28801 aaatgtacat atctcactca acctcacaat tatatttgat ctaactataa aaataatgtt
    28861 tatagatgat attaataaaa ctccaaatac acaaatcatt gctaatttat atgaggattt
    28921 attataatgg tctccaaaat gattacgtac atatcttccc tctatatctg aaaatccact
    28981 tttttctatt atattattta tttcttttat tactttttta tctgtttctt tttttatctt
    29041 cacaaaaact ttattataat cacttatccc tgttaattct tttaaatcct tttcattaaa
    29101 tataatttga attccacctg attgagattc tccatcttgc tctgatatat agctattttt
    29161 cattattcca gcgattctta cttttgtatt tatatattta tactctccat ctttatatac
    29221 aggaattttt atatctatta agtctcctat tttaggtgat tttataatct gagtattatt
    29281 tgacaattta attctagaat aaaaattatt taccaataaa acatttttat aatccctgtc
    29341 tgtataacta taaacatttt cgcctttatc tatatattta tctatattat ttaatagctc
    29401 tttattgtaa cctcgaatta aaactgtaga ctcattatta ttatttattt cagttctttt
    29461 tagctcatct aaataatctt cttctaagtc agcatttctt agatatcctt ttaaataaat
    29521 attgggttca acatctgtta catcttcaat agcttttatt tcatttaata aagaattatc
    29581 atatttagaa aatgtataat ttgcatttat tggtgaatat cccaaataaa tatcaaaatt
    29641 gccatatgat ttacttgtta tattagctga atctgactct tttccatata tgaattttgt
    29701 agaagttagt ctgcctataa ataaaacccc acatagtgat atcgtaatta ttattattat
    29761 tgatgtaacc ttattcctaa atatattttt aaaagctatc tcatttataa ttccaacaac
    29821 ttttttatgt gattttaaca acaaaagcct aggaatataa tttaacttat ctgtcttttt
    29881 tatagcatca attatagata aatttccagc tttatatatt ggtactacag aggctaatat
    29941 aactgctata attgacatga tgatagattc aattatagag tttgtattta tagttaattc
    30001 tgcactttta tcatatacta tcatgagacc taagtaagaa aaaactatac ctccaagtaa
    30061 accaattact atacctacag ataaaactac aatactctga ataaaaaata cctgtctaat
    30121 atttctcttg ctagctccaa cagctctaag taaaccaatt tgcttggtca tatctagtat
    30181 tattatgtta aacatattgt atattactaa tgttgcacat aataaaggga gtaagctttg
    30241 ctttattgaa taagttgttt tttttgaaat atttttcata tacatagaca tacttacttc
    30301 tgtatttgga taaaattgat tacttgttaa cttatatttt ctccctagat tcactacttt
    30361 ttgagaatct aaatcttttg tattcaattt taatgtaccc atatgagtta ttaattcata
    30421 tggaacaata tctttgccat tgtttgaata tgtaaaagct cttaccttat atttatttaa
    30481 attttcatag tattcatcag atttacttaa aataccaact attttaaatt gcttatcttt
    30541 actataaata gaattttcat tatttttatt tatatgctca ttaacaatct gaaaatcaat
    30601 agtttgattt aatttgacat ctaattccat tttgtctaaa actttttgtt ctattactaa
    30661 ttcattagaa gttctaggct ctctaccttt aactaactta tatctagtag aatctaaaaa
    30721 atctttattg taagagcata aatttagaga tgctccatta tctttactta taatttctcc
    30781 aaatttaagt acatcattga attcttttat atcttcttca ccattaagtt cttttactat
    30841 atcactattt atatcttcat aaaaagcatg ataatctccc gagtttttgt atgcatgatt
    30901 tatatctgat tgtccttgag attcattaat aacacttaat gaaaaaacta gcataacagc
    30961 aatccctata ctaagtatta atgataaagt ttttcctttt tgtctcttta aatatgacac
    31021 cgcaagttta atatttatca taatcagaat cctccttatt catatttaca agaaaaactc
    31081 tataacctaa aatagtaggt tatagagcac tattcattaa atactaacta actcgttgtg
    31141 ctagttaaat ttaattatta aaaatactag agttgagaaa atcacatttc atttgtaaaa
    31201 aactacatct agtactttca acatatttaa tagactgatt agtatttttt aataagctac
    31261 tgttcctttt ggagttgatc ctgcacaatc caccatacag tctatttgtg aaattattcc
    31321 atgcttatca taataccatt tacatggatc tgcttgcacc tcaacatctt gaagttctat
    31381 tttttcttcg atttttttta tatgtatcat aatacatatc cccctttact tttgttttat
    31441 atttattata actagttaaa ctagattata aactacatag tttttttgtt gtttccacat
    31501 aaactctttc taatccacaa taaattggta ctgcactttg gaatttacct gttacctttt
    31561 tattgataag tttacatctg gttgacatac aataatcaag tctagtacat ccatcacact
    31621 cttcattctt agatatataa atttttataa ggttcttaat ttttttatca tctaatccat
    31681 catatatatt tcctagtaaa atatctttat ctcctacaca tactgtacat ggatatacat
    31741 ctcctctagt atctattgca taactattta tccctccaaa acaatctcct tttttcttat
    31801 ttataaattg tttatctaaa atagatatat ctatatcagg ataatccttt ttaatattca
    31861 taattttact aatttgttca tttaatattt taatatgaga attatcccaa tttttatcca
    31921 taaaatctga aattggtgcg atatttttaa acccttgttt tgctatatca tatacactct
    31981 cataaagata cttaacagta tttgagttat atgtcattct tgccctaaca tatatacctt
    32041 tatctataag tctttttcca ttttccatta ctttttcata agtacctact ccgttagcat
    32101 ctattctatt tatatcatgt atattctttt ttccatcaat acttatcgat atgtttttta
    32161 cattctttgc tataaactct attatttcat catttataat agttccattt gtagttatat
    32221 caaataatat ctttttgtca ctcaatctat ctactaaatc cctatgtata tatttaatca
    32281 aatcaaaatt tataaatggt tctcctccat gtaaaacaat tgttgtataa tcactattac
    32341 tttctaattc tttattacaa ataaaatcta ttgttttatc agcagtttca taactcatat
    32401 tttctttttt tttatcatta ccttcataac aatatgtaca tctcaaattg cagtcttcag
    32461 ttacaaatat agtaaatttc aattaacttt ttcatctccc catacagctg tatttaaatt
    32521 gtgtttcatc atactacacc atctatccaa ttccaattca ttatccttaa ctgaatctaa
    32581 tatcgctggg caatgccaac aaaaaatatt tacatcacaa tctttacatt tttcaaagtt
    32641 atatggataa atactttcta atttaatcaa agactttaga tctcttgttt tattttcttt
    32701 tataactttt acaaattcat tgtcaaatat atttcccatt ttatagtcat cctttatcag
    32761 tgaaggacaa ggatatacat ctccatcata atttataaat atttgagagt ttcctgcatt
    32821 acatgcacaa catcccattt ttttattttt tttatcttta cacattttta attcattatc
    32881 taaaatatac ggaattgtaa ttggaagaac tgtatcttca attaaatagc tttctttatt
    32941 ttctaggcct cttcctgttg gaataaaata tctttcaaca aattctgttc caagcttttt
    33001 atttaaatct ttaaattgtt tatttaaatg agaatttttt tgtccaaata ccatagacag
    33061 ctttatatta ctgaatccat tgtcttttag cagattaaca gagcttatta ctttattaaa
    33121 tacacctttt cctcgtgttt cactacaagt attttcatct actccatcaa tactaatatc
    33181 tattttttca aaattagtta taataaaatc aacattatgt tcatctatta aagttccatt
    33241 tgtggataat attaatttgg tatcaggtaa tttttgtttt atatatttaa ttatttcaaa
    33301 aaaatcttct cttatcaatg gttctccacc agttataatt atatgaggag tatttaaaac
    33361 tgatattata tctacgatat tttttaaatc atatgtacta agtaaatctt tcttattaga
    33421 agaagattca acacaacaat gtttacaaaa taaattgcat ctatttgtca aacaaaaata
    33481 aattgcaaca ccattgctta acatatcaaa gtttaaattg ttacttttaa aaatttgatt
    33541 tttgttcata atatctataa gattaataat atattttttg tcactttcat catcaaaata
    33601 atttacaaaa tcataaattt ttattttatt ttcttgtcct aaaagaaaat acttatatat
    33661 ttcttcagac aatttaatat attttctaaa tttcttatta taaataatta ctagttgatt
    33721 ttttctataa ataattaaat cttctacatt aaaaatcatt tcttcagaat ctatcacaac
    33781 taagtcctcc tcaaattagt aaaatatttt tctttaatat ttattactaa tatcaacttt
    33841 actatctaat tagttattta attgttgttt ttatgttcct agttataaag tttatcaaat
    33901 ttacatttta tttttttata ctatatagaa cttttggtca ataatgttac catactaagg
    33961 tcgcatttgc agataaaaat aactctattt ttctaaattt atttaagata tatcatgcaa
    34021 ataatataac tataaaacct atcaacattt taaattcaaa caaatataaa tcacattttt
    34081 tgttctatta ttttattgag tactaaaaag gatgttatct tattagcata gcattcaacc
    34141 atttttatca cctccaaata tcctatgcct taaagatagc atcttctatt ttatctttca
    34201 atactactgc tccaactggg caatttagag ccccaactag aattagttcc tagttaatgg
    34261 tatataaata gtaattgtaa acttgttttt atctgagtat atttccacat ttccattata
    34321 tttttctact gaacttttta cactacttat tcctattcca tgtaaaaagg aatctttctt
    34381 acttgtaata accttattat tttttaatac aacttcattt atctttgtat tttcacattt
    34441 tattacaaat aacctattta taacagttcc tcttaattta atcttttttt gtatacttgt
    34501 gtccttaatc ttaatacaag cttctattgc attatctatt atatttgaaa atatactaca
    34561 tatatctggc atctctataa aattacattc taaaaaatta atatctacta gaaaatatat
    34621 attattcata tcacaaatag attttttatc acttaaaata acatctagaa tcatattctg
    34681 agtattaaat atagtattac attcttttat ttgcttattt atatctttaa tatacttatc
    34741 tgcaaactca tttttcccat aaacattctg aatacaaatg atatgattat tcatatcatg
    34801 atatagtttt cttattttca actgatattc ctgtaaattt aaataatatt tatattgcat
    34861 attcattctt ttttttgtaa tttcatattc tatctttaaa ctattatctt ttattattct
    34921 tcctattatg cttactaatg aaagatttga tagtaaaaat acagttgata ttgtaagtat
    34981 tattaaactc tctttagaat cgataatctt atctttaaaa ataaattcaa atattactat
    35041 tacaccaata atgtttgcta ttaatggaat agataaatat atacaatccc tcttgtttat
    35101 ttttgttttt aatctgataa acttaagcaa tggtattaat actattagta atgatttaga
    35161 tatcattatt aactctaact tcaacaaatt atcctctaat aaatcattca tattttttat
    35221 agaattaagt gtcattacta tacttaatcc aatactatca aatcc
//
LOCUS       DAEQAF010000035        35049 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.036, whole genome shotgun sequence.
ACCESSION   DAEQAF010000035 DAEQAF010000000
VERSION     DAEQAF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35049
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.036"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(121..1524)
                     /locus_tag="KRN00_001778"
     CDS             complement(121..1524)
                     /locus_tag="KRN00_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1827644.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(1508..2032)
                     /locus_tag="KRN00_001779"
     CDS             complement(1508..2032)
                     /locus_tag="KRN00_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1827645.1"
                     /translation="MHEQIDCCERKKRTIDIKGENMRELLKWVSIINRYNANYIDRKL
                     ADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGVK
                     DKRTWHLYPTEKSLGCYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDMN
                     EEAKLEAKENGRKI"
     gene            2312..2827
                     /locus_tag="KRN00_001780"
     CDS             2312..2827
                     /locus_tag="KRN00_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1827646.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            2876..3379
                     /locus_tag="KRN00_001781"
     CDS             2876..3379
                     /locus_tag="KRN00_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1827647.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILSNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINESDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            3376..4026
                     /locus_tag="KRN00_001782"
     CDS             3376..4026
                     /locus_tag="KRN00_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827648.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDNTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(4161..4940)
                     /locus_tag="KRN00_001783"
     CDS             complement(4161..4940)
                     /locus_tag="KRN00_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1827649.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(5052..5303)
                     /locus_tag="KRN00_001784"
     CDS             complement(5052..5303)
                     /locus_tag="KRN00_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBH1827650.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            complement(5632..6501)
                     /locus_tag="KRN00_001785"
     CDS             complement(5632..6501)
                     /locus_tag="KRN00_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1827651.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            complement(6839..7600)
                     /locus_tag="KRN00_001786"
     CDS             complement(6839..7600)
                     /locus_tag="KRN00_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827652.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQADIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            complement(7616..9151)
                     /locus_tag="KRN00_001787"
     CDS             complement(7616..9151)
                     /locus_tag="KRN00_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1827653.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVTIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            complement(9565..11805)
                     /locus_tag="KRN00_001788"
     CDS             complement(9565..11805)
                     /locus_tag="KRN00_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1827654.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEPEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLEAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            complement(12333..13133)
                     /locus_tag="KRN00_001789"
     CDS             complement(12333..13133)
                     /locus_tag="KRN00_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1827655.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGTHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            complement(13524..14399)
                     /gene="hslO"
                     /locus_tag="KRN00_001790"
     CDS             complement(13524..14399)
                     /gene="hslO"
                     /locus_tag="KRN00_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBH1827656.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            complement(14682..15428)
                     /locus_tag="KRN00_001791"
     CDS             complement(14682..15428)
                     /locus_tag="KRN00_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1827657.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLTKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            complement(15415..15660)
                     /locus_tag="KRN00_001792"
     CDS             complement(15415..15660)
                     /locus_tag="KRN00_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBH1827658.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            complement(15791..16909)
                     /locus_tag="KRN00_001793"
     CDS             complement(15791..16909)
                     /locus_tag="KRN00_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBH1827659.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYSKLLKYKEAID"
     gene            complement(17115..18308)
                     /locus_tag="KRN00_001794"
     CDS             complement(17115..18308)
                     /locus_tag="KRN00_001794"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBH1827660.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTDEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            18631..19512
                     /locus_tag="KRN00_001795"
     CDS             18631..19512
                     /locus_tag="KRN00_001795"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1827661.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            19937..20938
                     /locus_tag="KRN00_001796"
     CDS             19937..20938
                     /locus_tag="KRN00_001796"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBH1827662.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            21055..21942
                     /locus_tag="KRN00_001797"
     CDS             21055..21942
                     /locus_tag="KRN00_001797"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1827663.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            22009..22758
                     /locus_tag="KRN00_001798"
     CDS             22009..22758
                     /locus_tag="KRN00_001798"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH1827664.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKISEAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            22982..23698
                     /gene="dapD"
                     /locus_tag="KRN00_001799"
     CDS             22982..23698
                     /gene="dapD"
                     /locus_tag="KRN00_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBH1827665.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     SNGSYIFVGDYEDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(24150..25139)
                     /locus_tag="KRN00_001800"
     CDS             complement(24150..25139)
                     /locus_tag="KRN00_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBH1827666.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMIVLFLAVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLKMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAASRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLGEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            25579..26334
                     /locus_tag="KRN00_001801"
     CDS             25579..26334
                     /locus_tag="KRN00_001801"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBH1827667.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKILEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            complement(26765..28441)
                     /gene="bclA2"
                     /locus_tag="KRN00_001802"
     CDS             complement(26765..28441)
                     /gene="bclA2"
                     /locus_tag="KRN00_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBH1827668.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGANGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLATNNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(28819..29358)
                     /gene="hpt"
                     /locus_tag="KRN00_001803"
     CDS             complement(28819..29358)
                     /gene="hpt"
                     /locus_tag="KRN00_001803"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH1827669.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGRVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            complement(29686..30993)
                     /locus_tag="KRN00_001804"
     CDS             complement(29686..30993)
                     /locus_tag="KRN00_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBH1827670.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDAAEKAESLMDTVTIQELIKNVEEIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            complement(31418..33193)
                     /locus_tag="KRN00_001805"
     CDS             complement(31418..33193)
                     /locus_tag="KRN00_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827671.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKIDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLERMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            complement(33190..33327)
                     /locus_tag="KRN00_001806"
     CDS             complement(33190..33327)
                     /locus_tag="KRN00_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827672.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            complement(33405..33974)
                     /locus_tag="KRN00_001807"
     CDS             complement(33405..33974)
                     /locus_tag="KRN00_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1827673.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            complement(34158..34793)
                     /locus_tag="KRN00_001808"
     CDS             complement(34158..34793)
                     /locus_tag="KRN00_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBH1827674.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
BASE COUNT        11502 a         6066 c         4221 g        13260 t
ORIGIN      
        1 attagctttc tatactttct aaattagttt attatacttc tttagattaa ttttctacac
       61 ttcctaaatt agtttattat acttctttaa attaattttc tatacttctt aaatattgtc
      121 ttatacttct gcaatcttat tatggttact catcaaatta ttttgcttta tagtcaatga
      181 tttcatttca tgaactgcaa agtatataca taccattgcc gctgctgcat ctgctattgg
      241 tcctgcaaac attactccat caattcccat aaacattggt aaaattacta tcaatggaat
      301 taaaaataaa atttgacgag tcaaagaagt aaaaagtccc aacactgatt tcccaattga
      361 tgtaaagaaa gttgatgata ctatttgaac accatttata aatgttaaga acaagaaagt
      421 tctaaaataa tgttctgcaa atataaaata agtctcattt ccgttaccaa atatagacgt
      481 aatttgtctt gggaagaatt ggaaacatag gaatgcaata acagatataa tagttgcact
      541 tcccactgca aacttatatg cttcttttac acgattatac ttttcagccc cataattata
      601 ccctataatt ggttgcatac cttgtgatat accaataatt atagatataa aaatcatatt
      661 tactttaata atgataccga cacaagcaag tggaatctca cttccataaa ctgacctagc
      721 cccataatat gccaatgtat tattcataac tatctgtgtt acagtcattg ctaattgatt
      781 aaaacatgag cttgaaccta gcgcaaatat atgtttataa attatactat ctaatttaaa
      841 acttttctta tgtaatttaa tatgttgaaa attctttata taatgaacac ttattccaaa
      901 agatataagt tgcccaataa cagttgctaa agcagaccca gcaattccca tattaaaaac
      961 aaaaatgaat aatggattca aaattgtatt aataactgct cctattaaca tacaaaacat
     1021 agaagctttt ggtctcccat ctgcaagtat caacttactc attccagtgg acattataag
     1081 aaatggtaat ccaattgatg taatttttgt atatgtgtgt gcataaggta gtatttctga
     1141 tgtagagcca aagaatttta atagtggtgt taaaaatatt gatactacta taaataaact
     1201 tattccaaaa acagccatca agcatataga atttcctgct gcttttgtag ctttttctga
     1261 atttttagca cctaattcca atgaacactt agacgctcct ccaattccta acaataatgc
     1321 aattgcggta catattgttg ttagtggaaa agtgacattt gtagcagcat tacccaatac
     1381 accaacacct tgcccaataa atatttggtc aacaatgtta tataaagcac ttactaacat
     1441 tgctataata ctaggaattg cgtacttagt taataacttt gaaacctttt catattccaa
     1501 tggctcctta tatttttctt ccattttcct tcgcctccaa ttttgcttct tcattcatat
     1561 caatagccaa aaatgcaact ttctttaaca ttgacataaa caactcttgc tcttctttct
     1621 caaatgaact caacaactcc tcaacatacc catttgttat ttttagtatt tcatcataac
     1681 atcctaaaga tttttctgta ggatataaat gccatgttct tttatccttt acacctggtt
     1741 ctcttgttat aaagccttct ttttctaaat ttgccaaagc tcttgttata ttactaggat
     1801 tcacaagaat tttctcaaat atagtgtcct gtgtaatacc tggattatta catatgtgta
     1861 atacatagaa atattggcta ttattgattc caatatccgc caatttcctg tcaatataat
     1921 ttgcattgta tctatttata atggaaaccc attttaatag ctctctcata ttctctcctt
     1981 taatatctat tgtccttttt ttgcgttcgc aacaatctat ttgctcatgc aattattcta
     2041 ctgctaattt tatactttgt caatagcaca caagtttata tttaaaccat aaagttacta
     2101 taaattttat atattagact cttactttga tttaactatt tttaaatctt tattgatatt
     2161 taattacctt ttatattaat ttttttgcat atttatcaat aactcctaat tctttttagc
     2221 ttatcttaaa aagcatcttg acgtaagatt tattatctgt aataataaat atatcgaatc
     2281 gatatatatc taattgatac caggaggtaa tatgttagaa tacattattt taggattttt
     2341 aatggaaaaa gaattaagtg gatacgactt aaaacaaata atgtcagaaa gtacctcgta
     2401 cttttttgac gccagctttg gaagtatcta tcctgcactt aaaagattag aaacaaaagg
     2461 atatatacac tatcacgaag ttatagatgg tagcaaatta aaaaaattat attccataac
     2521 taatactggt aaagaagtat ttcttgaatg gctaaagaaa cctataaatt tttctaaaac
     2581 aaagcaagac caccttgtta atatattctt ttacaagtat ctacccaaag aaataattga
     2641 aacaaactta aaaatgttaa taactgaagt agaattactt ctaaataaat taagtaaaca
     2701 aaaaaatgat gcagaagaaa atcattgtgt tgaccaatat acatatatgt atgcaacaat
     2761 gatttatgga gttgactatt ataattttgt tattaattgg tgtaaagatt tactgaaaaa
     2821 tctataagat ataattttta gaagtaaaca tacataataa aaggagatgg actttatgag
     2881 gcttttaata catgatttaa ctgacaaaga attagaaaag ttattaccca aacttgatga
     2941 caatataaaa atactttcaa acacaaaaga aatccataaa tgtattggtt gttttggttg
     3001 ctggattaaa actccttctg aatgtgttgt aaaagattat tacagcaaca tgggtaaact
     3061 tataaatgaa tctgatggaa ttattataat aagcagatgc tgttacggag ggtttagccc
     3121 ttttgtcaaa aacgtacttg ataaaagcat taattatatt cttccatact ttgtaataaa
     3181 agataatatg atgcgtcata aaagcagata tgataaacag ataaatttaa aagctatatt
     3241 ctatggagat tgtattacag aagctgaaaa agaaactgct acgaaattag taaatggaaa
     3301 tgctataaat ttcaatataa aagaacactc tgtttgtttc tatgaaaata tacaagatat
     3361 aagaggtgaa tccatatgaa tatagtaatg ataaatggta gtccaaaagt aaataaaaat
     3421 aattcacagt attttttatc tgaattaaaa caacttattc aaaatgataa taaagttttt
     3481 acatttaaag tagataacac atctaagtat cctgacgctc ttaatgccat acttaattgt
     3541 gatagattaa taatcgcatc tcctctttat gtagatggta ttccgtctca tttacttcat
     3601 tttttagaga aatgtgaaaa atttttaaaa acacaaaata aaaaacctat tccagtgtat
     3661 gcaatagtta actgtggatt caatgaaggt gaacataatc atttggcaat tcaaatgata
     3721 gagcattggt gtaaaaaaat caactttaca tgggttcaag gtattggaat tggagctggg
     3781 gagatgtttg gttcactaga atccgtacct ttgggtaaag gacctaaaaa agatttagga
     3841 attgcattaa aagaactttc aaaaaatata cttagtgata atatacatat agatgattcc
     3901 aacaaaagta ctatttttat ttcacctaac ttccctagat tcctatataa acttatgggg
     3961 aatcatcaat ggaatactca ggctaaatca aatggattga ctaaaagtga tatactaaag
     4021 aaataaaatt ttacttcaac aaatactaaa aaccgtcaag cacgaataaa ctattcatct
     4081 tgacggtttt ttatgttatt tatattcact agacatggga taattcacta caacattgat
     4141 tatctagtct aatatttatc ttattctttt tgtaaaatcc aagttgctcc aacaaggtcc
     4201 tgctgtaaat cagtatattc atttttttgg ctaataacat attgttcaaa catatctttt
     4261 tgagaaggat attttttaat tagctcattt gcacgagtta taatccagtt catttcctct
     4321 tcaacatcat tttcaagttc taaacatggt atacattcaa ttagtttcag acctaattct
     4381 ttgaacaata tacaccactc attgtaagtg ggatacaccc tctcaaaatt aagctgttca
     4441 tttgtagatt tatctactac atatgcatca tcaattaaaa tgaacccctt actttttatt
     4501 gtaggtaata gcttacttat agtttcttta taattaccta aaatatcccc tacagctcca
     4561 aaaatcacac aatcataatc atgctcaatt tttacagaac tattagcatc attcatttca
     4621 aaatcacaca aagcatcaac cttatattca atagcctttc ttctcgcata atcaataaat
     4681 tcaggtatca aatcaatacc tttgatatgt atattcaact cttttgcaag cttcacagat
     4741 acagcacctt ttccacaagc taaatccaaa acttttgtat cttcattaaa aggtatatgc
     4801 tttctaaata attgtaacat ttgttctggt gaacttccta attcccaaaa atcttgtaat
     4861 aaataaggca aataaggtaa aatatcagta gtatcagaag ttagtgactc tgccaatttt
     4921 tcttttacag tatcattcat tttttcaacc tccaaaattt aaattattat tcaaaagtaa
     4981 tattatttta tatacttctt cataggtact acaaacagtg gaaaatgctt ttgacctttg
     5041 tattttgcaa ttcatttctt ttctttatga gctgtaataa ttgtataact gtgagcgttt
     5101 actgttataa tacaatcata tacacttata taccagtttt ttccctttct attaataatg
     5161 gcatttggag attctatttt agttttacac cagttcacta catcatttgt ctccaaagaa
     5221 agatttttct taattcttac aacgcctaac tctgttgtat gcaatctatc taggttttta
     5281 agtaattcgt tttctacatt catttttatt aaaacacctt atcctttgca aaattaaatc
     5341 tattatttag tactatttta tcatagtatt gtgtatttta tcataatctt atagtgaaac
     5401 tatttctttc ctacagatta taaattattt atgaatacac accattatag aacttttcct
     5461 atgcaaaatt aaatctatta tttaacacta ttttgtcata gtattgtgta ttttatcata
     5521 atcttatagt aaaattattt ctttcctaca gactataaat tatttataaa tacatactgc
     5581 tgtaaaactt tgcctatata aatccatcta ctttatacat aataccttct tttaaatgat
     5641 tggaacccaa aactgaattt cactcaaacc attctcatca gttttttctc catattttac
     5701 aaagtcatat aaattatttt cattaaactg gcaacttgaa ttagggaacc attcttgata
     5761 gatatattct acaacatttt gcatactatc ctcatttttc ccaataaaag taaaaacaat
     5821 ataattactt ttcggtaata cgaatttttc cattccatta ggtaatttgc caaaagtagc
     5881 tacttgagca cctgcaatgt atgtaaatgt aggagtattc tcaatctctt taaaattgct
     5941 ataatcacta actccaatta aaaaacctaa atctacctta ttttctatca tctctttatt
     6001 tttatgcaaa tccctccagc attttccaat aatatgaaat ccttttctta ctttaccaga
     6061 atagccaaca atatttatat ctgcacaatt aactttttta acatctaaaa ccatatctcc
     6121 acgtaatttt tttctattat gaatatcaaa ttttaattgt agtggtaaaa aatcttgatg
     6181 tcttctaaaa aaattaggac tacgtttaaa cattttttta aaccctcttg aaaaagagcg
     6241 ttgtgtatca taccccgaga ttaaagcaat ctcaataatt ggtttttctg taaaaattag
     6301 cattctcgct gcttcagtaa gtctacgtct ttgtatataa ttatgtacac taaatccgac
     6361 aactgatgta aacattctat gtaaatggta ttttgaatag cctatctctt tagaaattac
     6421 atttaaatct aacatctcat ctaaaagatg tttttctata taatctaaag ttttttcaat
     6481 ggtaatcaaa ttgttatcca tatagcaccc ctcctatttt aaagatagca tattatttta
     6541 ttttgttttt cacattcttt gctaatattt tgatttattt tatggcacac aaaagacact
     6601 tctatttgaa gtgcctatct actctgtata ttgagcttct tatttcaatt tattataatc
     6661 ttcaacagat acaggttcca gccatttatt gaaatcacct tcagcagtta ccttgtctac
     6721 agccaactgc taaattccct tctatacctt aatctaactt ttccacttca agtatacaac
     6781 ttgaagttag ctctaaatca atagttttta tcacaacaat ttgattttaa atttaaattt
     6841 attcttttaa attatcatca tctattatag attttcttat attcaataac tggtctacaa
     6901 attggttagc aggagtattt aaaatattct caggagtatc atactgttga acaactccat
     6961 gatttaatac caaagtcttt gttcccaaaa tcaaagcttc ataaatatca tgcgtaataa
     7021 agataatcgt aactcctgtt tttttatgaa tttcttttat ctctttttgt aattgctttc
     7081 gtgtaatctc atcaactgca ccaaaaggtt catccattaa taaaatttct ggagaagaag
     7141 ctaaagctct tgcaatccct acacgttgtt gctgaccacc tgacaattct gatgggtaac
     7201 gcactttcat atcatttggc aatcccacta tttccatcca cttgtttaca gcacttttta
     7261 cttctaattt attcttttta cttaggagat ttggtacata tgaaatattt tcttcaacag
     7321 tcatatgagg aaaaagaaca cttccctgta cacaatatcc tattcttcgt cttaatttaa
     7381 ttaagtcctc gtttttgata tctgcttggt ttatcaaaat atttcctcca tctggcaaaa
     7441 tcagaccatt aatcattttt aagagtgttg tcttaccaga accagacgaa ccaattacag
     7501 tcaaaaactc tcctttttct atatctaaat taagattatc tattatagtt ttatcattat
     7561 attgtttttt aatattttta aattgtataa taggtgtcat tatatttcct ccaatttata
     7621 aaagaccttt cttattcaga aactcacgag caacttctct aggttctaaa ttgttgtttt
     7681 ctacgtcata attcatttta gccatttctt tatcagtcaa aatatctcca accatcttaa
     7741 atacctttga tagttctgga ttttcctcta atacttccaa acgaacaaca tttccacatt
     7801 gataagatgg gtagaaattt ttatcatctt ttagaactac aacatctgaa acactatact
     7861 gaccatcagt tgtaaatata ggcattacgt caatcttacc ttcattaata gcttggtatt
     7921 ttaatccaat atctaaatca actgtatctt taaagttcag cccatatgta ttacacaatg
     7981 gagtatatcc atcctctctc tcataaaagt catattcagc tccaaatgtc aatttagaag
     8041 atacatcttt taagtccgtt atatttttta aattatattt atctgcaact tcttttctaa
     8101 ctgctaatgc atagctatta gaaaaaccat acataccagt ccattgcatt ttaagtttag
     8161 ttttgtattc cgactgtagt ttactaaaca tactttcagt atataattca tttttcttaa
     8221 gtaccatatt ccagcctgta cctgtatact ctggataaat gtcaaattct ccattctcca
     8281 tagctggctg gatattagat gttccccctc ctacaccttg tgtaatttcc acgtttagac
     8341 ctgtgttttt ttcaattaaa atatccaaca tctcaccaag aatatattgt tcagtcatag
     8401 gtttagtagc aatatgaata gtttgagtct ttgaaggatt aaataaataa gacgtaaaga
     8461 tagttactat aagaataagg cttcctagaa tggcaaaaac ttttttccta tttttctttt
     8521 ttctttttcg ttgaaaaaat ttttctacca gccctaaaat aaaatcaaat attaaagcta
     8581 atagagcaat aagtatactt ccagtaattg tcattattgt gttatttgtc gtgattcctc
     8641 tatatatggc tacacctaga cctccagcac ctataaatga agcgatacca gctaatgcaa
     8701 ttgtcataat caccatattt ctaataccag acataataac aggtagggct aacggaagtt
     8761 ttattttata caatatctga aaatctgtac ttcccattcc cctagctgct tcaagaatat
     8821 ttttatccac attagtaatt ccagtatatg tatttctaac cattggcaat aatgcataaa
     8881 tggtaagtgc aataacagca gtagtatttc caattccgga aaatggtatc agaaatccta
     8941 gcatagaaat agatggaatg gtgtatagaa aattgatagt tcccaatata ggtttagaag
     9001 aattatgaaa ttcacttaca ataataccaa ttataccacc caaaacaatc gcaattatta
     9061 tagaaataat agaaatcatc aaatgttcta tggatagctt tataaaaaaa tcacttcttt
     9121 cagataataa ggttagaata tcatttatca tccatctctc tccttttata agttttactt
     9181 aacaagattt aaattttaat gtagttaatc tttattgttt atacatcagc aaatcgtcat
     9241 caaattattt cacaaattat atattaagat tataatctga acctcccatg actgaagtca
     9301 caagtgtgta tagccatttt ttaatcaaac ttgcaagtag acacaaaaaa gtaactatta
     9361 gagactccat cctcgatatt ctctataaaa ataagaaaaa aggtcagaac cgttaaaata
     9421 ctaaaattta aacacatttc tgacacttta tttaattaaa tttgaatatt tctcacatta
     9481 tttattactg ttaagtttaa ttatcatttt atatacccat tatatttatt aaaatatcat
     9541 tataatttta ttatatttta tttattatac tatatatttt gctgttaatg atattttatt
     9601 gttacataat tgttttggaa taccttcaaa tattactctc ccgccttttg ttcctccttc
     9661 aggtcccagc tcaataatcc aatcagctct tttaattaca tctatattgt gttcaattat
     9721 tatgaccgta tttccattat ctacaatctc ttcaattata cttataaaat tctcaatatc
     9781 agccatatga agacctgttg ttggttcatc taatatatac actgaacttt ccttatttaa
     9841 ttcactagca agctttaatc tttgacactc tcctccagac aaagtatcaa gagtttgtcc
     9901 taaagtaagg tatccaatac ccattttttc aatacattgt aatttcgttt taatctgttt
     9961 taaattaaaa aactcaattg cctctaaaac agacatttca agaacttcaa ttatattctt
    10021 cccttgaaac ctatattcta aaacttcttt tttaaatttt ttaccttcac aaacattgca
    10081 ggtactcttt atactctcca taaaagcaag attcatttct actattccag aacccttaca
    10141 gttatcacaa gctccttctg aatttgaact gaataaagaa gcatttacgc catttgtttt
    10201 tgaaaatatg cttcttatgt tgttcataat tccactatat gttgccaaac tcgaccttga
    10261 atttgctgaa acagggcttt ggtctataag tacagcacta ggattttgct ttaaaaattc
    10321 atccttaatc aatgtacttt tacctgctcc tgctactcca gtaactaaag tcaatacacc
    10381 tttaggtatc ttaatagata cattttttaa attgttttta ttacaatttt taacttctaa
    10441 atatccacta tgttctctta cactttcttt aataggaaga aatttactta aagcattccc
    10501 tgtcaaagta ccacttgtaa gtagattttc ataactgcct tcatacacaa cttctccacc
    10561 atacttacct gcctttggtc ctacatctac aatatggtct gcaatcttaa taacatctgg
    10621 gtcatgttca acaactataa ttgtattccc tttatcacgc aattttttta aaagattatt
    10681 taatttatac acatcttttg gatgaagtcc tacacttggt tcatcaaaaa tatacattaa
    10741 atcaacaaga ttactattta aatacttaac catctttata cgctgagatt cccctcctga
    10801 tagagaagat gtctctctat ctagtgttaa atatccaaga cctatatcta tgatactgtt
    10861 taacttttct attattcctt taattaaagg ttgtgcttct ggctcatcta tacttttaat
    10921 aacttcagcc aattcatcaa tttgcatact agttaaatct gctatattat aaccattaat
    10981 taaagaccta tatactcttt cattaagtct tcttccatca catataggac atctatcttc
    11041 tataagaagt ttactcaatt ttttcttagt agcttcagat atttctccct ctctacttaa
    11101 gtataggcga ttaaatttaa ccattaatcc ctcatatgtc atgttagttt gaccagcatt
    11161 ttctatctta atcttttctg ctttaccatg caaaaacttt tccaattcta cttctgaata
    11221 atcacatatc ctcttattaa tatcaaaaaa tcctgattca gcgaatatat tccaatgcca
    11281 agaacccact ccaaaccctg aaagcaatat agcaccttca tttaatgatt tattcatatc
    11341 aagaatttgg ttcatattag gaactagctt ttttccaagc ccatgacagt gtggacacat
    11401 accatcaata ttattaaaag aaaacatatt ggcattacct atatactcac taccaaacct
    11461 tgaatataaa gctcttaaaa aggaatttac atctgtaata gtacctaggg ttgaccttga
    11521 atttccacca agtctacttt ggtctatgat aattggtgtt gacaaatttt ctatacaatc
    11581 agctttaacc tctccatact taggtaaaaa acttcttaca aatgtactaa acctttcatt
    11641 tagttggcgt tgtgattctt ttgcaattgt ctcaaataca atagatgact ttccagaacc
    11701 cgacacccct gtgaatatgg ttatttttct ttttggtatt tttaaggaaa tattgttcaa
    11761 attgttctct ttgcaacctt ttaaaattat aaattcattg ttcatatttt acctcctgca
    11821 ttatttttct ttaaattatt tagagaaaat cgtaataata gttgttagtt atacataagt
    11881 gaaatactat tttattagat tactcctttt tttataaaca caggtcaaat tatagcatgt
    11941 agattttatc tggtagtata gtgtagggtt tggattttta taaaaaatac agttatttta
    12001 tttaagcgta attacatcta ttctacctaa atatcatcat tatatatgag tgttaaatta
    12061 tataaaattc ttaagttaat aatctcaaaa tggtattagt tacataaaaa aagtatcttg
    12121 cctatgattt taaaaccata aataagatac tatgttttac actgtttctt ctttcacaaa
    12181 taattctata caattactca acttaacttt aaaattttaa acattaaaaa cctctatctt
    12241 taaatcttta aataaaacta aatttccaat accttcaaaa ctatagaaaa ttccaatcaa
    12301 cttatcaaac ataacttact acttataaga aattaatctt cacttaatac agacgtaagt
    12361 tcagggtcat ttagaagatg ttcaaaataa ctatgtgccg aaatatatcc tataccatac
    12421 attttacgct ttgaatttac aaccttatat tcataacaag cactcttaac cttattgtag
    12481 tcatcaaaat ccattgcttt atagatagct ctttcatttc ttggtatata ctttacatat
    12541 tttggcttaa caaaatacaa gtcatctttt atcttacctt cacgtttaag tttctttaaa
    12601 acttccccat tctttctatg cattatatgg tcatcatact tatagtgatg ggctatatgg
    12661 gtcacattgc ctttaaactt atgttcaaaa tccaatatag tcttttccat taattcataa
    12721 tgtgtgcctt cctttttatc tatatctgca agtataatca cattttgagg tttcactcca
    12781 agctctctca aagctgattt aaactcgtta tttctaagtt cttccttttg cttcctagtt
    12841 aaatttctaa attttgtgtt agctttgaaa acgttaactc cagaaccatc tgatactaat
    12901 accacatata cattatcaac accacactgt tttatagcat ctacaatggc acttcctccc
    12961 cataaaacct catcatcttg atgttgagga taaaacactg ctgctgattt aaattttcta
    13021 ctattactct caggaatagg tatttcaagt tttccgttaa aattctttgc aattaaaaat
    13081 atcatcaata atattaatat acttattcct atgtacttcg ttttactttc catatttaaa
    13141 attttctcct tcttctgaac ctcccatgat taaagtcaca gggttactac ttcatagaat
    13201 ttcgtataat caactcaaat atcttataaa cctttgtgtc aatcaggtct aaatatacaa
    13261 attattttac aatattttat tgtttcatac aatctttgac acgaactata ataaaataaa
    13321 aaagccttct aactgcaaca ttgcaaacat tacagccaga aagcttctta attcttaaaa
    13381 tttattaagc ttaaaaattt attaaactta ttttttaata taaatatgtc tattattaat
    13441 aaattatact ttaattacta tatcaatacg actttactat attactataa cattacttat
    13501 atcaatacaa ctatttttat agtctacatt tcctttaaaa tttcaagcaa ctcttcttca
    13561 ctatacatat acttcttatt acagaactgg caaccaactt ctgctttttt atcttcttct
    13621 attatttgag ccaatgattt tttaccaatt gcaaccaaag cagtttttac tctttctttt
    13681 gaacattcac acataaaccc aacttcacag gtatcaagta ttttaggttc caaaccatcc
    13741 aaaacaatat ttaatatatc ctctggtgat tttccttctt ttaacatgtt agttatagaa
    13801 ggtaatttag ctacattttc ctctaactta gcaatagtct cttcttctgc atctggcatt
    13861 aattgaacta taaatcctcc agcaaactct acttcatctt cttttgtaag aacacctaaa
    13921 gctactactg atggagtctg ctctgataca gcaaaataat aagtaaagtc ttctgcaatt
    13981 tctccactta ccaatggata agtcccatta tatggttctc taagacctaa atcttttata
    14041 acttttacaa caccttctgt acctactgct gctgctacat ttaactttcc atttggatag
    14101 tcttcaacct ctacctgtgg atttcctaca tatcctttta ccattccctt agaatctgat
    14161 gtggcgataa tagttccaat tggacctcca ccttttatta ttacagtcaa tttatcacta
    14221 tcatttttca tcattaatcc cattatagat gtggctgtta atgttcttcc aagtgctgct
    14281 gttgctactt ttgtagtttc atgtaatctt ctagcttctt ctactgtatt tctagtagtt
    14341 gcgacaaatg ctctaacttg accatttcct gatgtcgctc ttagtacata atctctcatt
    14401 aatattcctc catgtcccgt taattgtctt atttttatta tattactacc ttaatttatc
    14461 tataaatact tatctatctt aaccttgggc aaaacccatt ttattttaat tttactaagt
    14521 aatagttact atattttaat ttttatctat agaactttat aattattaaa aaataaaagt
    14581 cataaagtat catcacttta cttttaatct ataaaactgc attttctata tttttatatc
    14641 atggttattt ttaataatta tcttatatag tcaagaatat cttatttttt acatacaaag
    14701 aagattcttt gactttcttc actaggtttg tcaaatgtaa aatccccata atattttata
    14761 tccttaaatc cagatttttc aagcatatca actatctcat cttcagtata tgctctttgt
    14821 tggtgtatct cttcaaatct ttcaaacttt ccacattcat ctttaataaa gaatgtaagt
    14881 tccatttcaa ttagattctc ttcttcatca aagtaatttt gccacatata cgctatatct
    14941 tctctatttt ctccatacat gttatttccc aatatgttgg ctaatttata aaaagaactt
    15001 atatcaaata tgaatattcc atctttcttt aataattcat atgtctttga aaatacattt
    15061 tccaaatcat catcataagt tatataatta aatccatcac aagcacaaag tacacagtcc
    15121 aaatcagata tttcaaaatc aagctctgat atatcttgtt gaagtaaaac taattctact
    15181 ccttcttttt ctgccttttc tcttgctaca ctaagcatct catcagatat atctatacca
    15241 gctatatcgt aatttttttt agtcaatgga attgtaagat tacccgtgcc acatgccaat
    15301 tccaatatat tttttacttt tacaccttca ctatctatta tatcttctat atatttaacc
    15361 caaccattat aatcaacttc attcataagt tcatcatata caaacgcaaa atcactatat
    15421 tgactcatcc tttttattct gctcctccac aatcttttta agcctctttt tgcgtgatgt
    15481 aagcatacct ccaattcttc ctgcttcctt agctgtaagt cctgcccatc cacgttcacc
    15541 aactttatcc ataagaccta gttctgaggc tatctcatat ttcattatat catcatttgt
    15601 caatatttta gtattcttgc cattagttat cttcttttct ctttgtactt tttctttcaa
    15661 aaaaatcacc ccttcttatt tgtatttttg tcaattaaaa taaatttata caaatatgta
    15721 aggggtattt attaatacac tttttttaaa tttaggtatt tatgcttttt aatctttata
    15781 atttattttc ctaatctatt gcttctttgt attttaataa ttttgaataa acattcaatg
    15841 catttacaca tatcttttca tcaaaattaa agtttatatt atgaagacca tttacaaatc
    15901 ctttttcttc gtttcttgaa cccaacataa aaaataatcc tggaacttct ttttgataat
    15961 aagaaaaatc ttctgatatc ataagtggct ctaactctac aacagtatca cttccaatag
    16021 cctctacaaa ctcttgatac aaatccttgt catttttaac agcaatataa tcatctataa
    16081 tatttatatt aaccttacag ttataagcta attcaaaccc tctagcaagt tctctaactc
    16141 taagcttcat tttctcatac acttctgggc tgaaacatct catagtacct tccatcttta
    16201 tattttcagc tattatattt cttctagctc ccccttcaat tctaccaata gtcaacactg
    16261 cattgtctat tgggcttata tttctagaca ctatagtttg aagtgagctt acaaagtttg
    16321 aagctatcac tataccatca ataccatttt gtggcatagc cccatgtcca cttttagaca
    16381 ctatttctat gtcaatatct cctatttgag ccataaaata gccctctctt gtacctacat
    16441 aaccttctgg taactctgga tatatatgaa gcccatatat ttcatcaata ttgtattttc
    16501 taagcactcc ttcatctatt aaagcttttg ctcccccagg accttcttct gctggttgga
    16561 atataaatac tatattatca tttaagtctt ctttattatc atttaaatac tcaattaatc
    16621 caagtaatat agtagcatgt ccatcatgac cacataaatg ttttacccct tcttcactat
    16681 gaagaccatc tatgtcagct ctaaaagcaa tatctttttt aggtctttta ccttctatta
    16741 cacctactat acctgtttct aaataaactt catactcaat tcctaattta tcaagataat
    16801 ctcttatata ttttgaagtc ttatactctt ttctcccaat ctctgcaata ggatttaatg
    16861 acttcctatg tttataaagt tgttcttgta aatatgatgc ctctctcatg taatctcctc
    16921 caatttctaa tttattaaaa aatatttcta tatttcttta taattaaaat attatatagc
    16981 atgttatact aattaaaaat aaaaagctaa attgaatata aaaatatttt gcattattaa
    17041 ataattcacc attaataata attcccctgt ttcataaatc aaaacagagg aattattatt
    17101 ggaaaatttt atttttagca agagaagaaa tgtttagcaa gtccaccctt agctgtttct
    17161 ttgtacttat ccatcatatc tataccagtt tctttcattg tttcaacaac ttggtctaag
    17221 gagacagaat gtgagccatc agttaataat gcataattag ctgcatcata agctctttga
    17281 gctgccattg catttctttc tatacatgga atttgaacat atccatatac agggtcacaa
    17341 gtcattccta aatgatgttc aagtgctatt tctgccgcat attcaatatg gtctatagtt
    17401 ccacctttta agtatgctac tgctgctgct gccatagaac aagcggctcc aacttcacct
    17461 tgacacccta cctctgctcc agatattgaa gcgttagttt ttattatatt acctattatt
    17521 ccagctacaa gtagtgcttc aattattttt tcgtcatcat aattatagaa atcctgcatt
    17581 gcaaagaata ttcctggtat tactccagca gaaccacaag ttggtgctgt aactattata
    17641 ttaccagaag cgttttgctc tgaagctgct agtgcatatg catatacaag tgttgagaag
    17701 ctcttatctt ttttatatgc attataaaat gtacttgctc ttctttttaa taataacttg
    17761 cctggtatta tttcatctgt acttagtcca tcatcaatag attttctcat agcatctttt
    17821 atagttttta tataatcttt tatgtctttt ggttcacatt ccaacacaaa atctaccaaa
    17881 gtcttattat tttctttgca ccattttact atctcatcca tagtatctaa gtgatatata
    17941 ctattgcttt tactgtttct ttgaccttct tctgctatag ttcctccacc tacagaatat
    18001 acagtccatt catctgttac atttttatct ttatctaaag cttcaaactt catcccattt
    18061 gggtgaaaat cttttataat atcttcttcc caaacaattt cgactttttt aggtgctata
    18121 gttttttcaa ttatatagtc agttaagtga cctttccctg tggctgccaa actaccatat
    18181 aatattgctc taaaactttc tgcatctggg ttttcattct taaatctctc tgctgctctt
    18241 tgtggtccca tagtatgaga acttgaaggt ccacttccta ttttaaaaag ttcctttaaa
    18301 gtatccatat tattcctcct aaatttacgg tattattgct tattgttaga ttttacgcac
    18361 atatttatta taacctaaat atattaatta ttagttatta aattctcata aaatttattt
    18421 tttatttcca ttttggtata ttttattaaa ttaatatgca tattttgaga ataaaacatt
    18481 tatttaaaat ttttctaata ttaatataat ataaatatct tatttaaaca gttaagatat
    18541 taactatacc tattaaaatt aattaatttg tactataatt attattgtac ttaaaaaatt
    18601 aaatttagat aaaaaaggag atttgattat atgttattta aaggttctgc tgttgcttta
    18661 gttaccccat ttacagagga taataatgtc aactttgaaa aattaggtga attaatcgaa
    18721 tatcacattg agaatggcac agatgcacta gttgtttgtg gaacaacagg tgaggcgact
    18781 actatgagtg aatctgaaat ttttgctgta ataaaatata cagttgaaaa agttaataag
    18841 agaatacctg ttatagcagg tactggttca aacaatacta tgttgtctgt tcatatgagt
    18901 caagaagctg aaaaattagg ggtggatggt cttttaataa taactcctta ctataataag
    18961 actaatgaga aaggtcttaa acttcacttt gaaacaatag caaatagcgt taagttgcca
    19021 attattttat acaacgtacc aggaagaact aaagtgaata taaagccatc tgttgtggct
    19081 gaacttgcta aaatagataa tatagttgct gtgaaggaag caagtggaga cttagctcaa
    19141 gttgcagaaa tagctaaatt agtacctaaa gactttgcta tatactccgg taatgatgat
    19201 actatactac cactattatc attaggtgga agtggtgtta tctctgtact tgctaacata
    19261 tgtcctaaag aaacacatga tttagtaact aaattctttg aaggtgatat tgaaggctca
    19321 aaaaaattac aacttgatat ggatgcttta attgctgcct tatttataga agtaaatcca
    19381 gttcctgtta aaactgccat gaacatttta ggttttaatg ttggtgattt aagacttcct
    19441 ctagctgaaa tggaagaaac taatcttaat gtgttaaaac aagaattgac aaattttgga
    19501 tttaaatttt agcaatattt atataaataa gttgattttt tcttaaatat gtattattat
    19561 tagaataatc aaattttaat atcctattaa cctagggtag aggtagctgt aactaagagt
    19621 atccaatagt agctggcagg tgttaatgat tggaaaaagg atttacagcc gaagaaaata
    19681 tttcttgcaa taatattttc tgggattgca cataacatgt gtaatactgt cacttatttt
    19741 tgtaggtgat gagctacagg gtttactttg agtgataaat tagacgtaca aagtatacct
    19801 ttgtacgttt tttgtatata attaaagttg ttaatataat attaaagttt ttggatatat
    19861 aaaaatatta acatatctta cttgtataac taaaataaaa taatgtttta ataatttaaa
    19921 attggggtga atttatatga aaaaagtaaa tgtagcaata gttggtgcta ctggaatggt
    19981 aggtagaaca tttttaaaag tattagaaga aagaaatttt ccaatagaaa atctattttt
    20041 attctcttct tctaaatcag ctggttctaa agtaatgttt tgtggtaaag aatatatagt
    20101 agaagaatta aaggaaactt catttactga tagaggcata caaatagcat tattctctgc
    20161 tggtggaagt attagtgaaa agtatgctcc aatagctgct tcaaatggaa tcttagtagt
    20221 agataactct agtcaatgga gaatgaatcc agatgtgcct ttagtagttc ctgaggttaa
    20281 tccagaagcc ataaaaaatc ataagggtat aatagctaat cctaactgct ctactataca
    20341 agctatggtt ccccttaaag ctcttgatga taaatacaaa attaagagag ttgtttactc
    20401 tacttaccaa gctgtatctg gttctggtgt taaaggtgtt gaagatttag agaaaggaat
    20461 gaacggtaat cctactggat tctaccctca tcaaatctct tacaactgtc ttcctcatat
    20521 agattcattc actgaaaatg gatacactaa agaagaaatg aaaatggtaa atgaaactat
    20581 gaaaatactt gataactacg atttaaaaat aactgcaact actgtaagag ttccagtaaa
    20641 aaatggtcat agtgaatcta taaatgttga gtttaacaat ccatttgagt tagatgattt
    20701 agtaaaaaca cttgaagaag ctccaggtgt tgtagtagtt gataatcctg ctaaaaacga
    20761 atatccaact gctgtagaat ttgatgatag agatgaagta tttgttggaa gaataagaag
    20821 agattttagt gttgataatg gtgtaaatct ttgggttgtt gctgataata taagaaaagg
    20881 tgctgcaact aacgcaattc aaatagctga aatggcttta tcatacgatt tagtataata
    20941 tacaaacttg tataaatata taattttgta aaatattaat agtaactcaa aaacaagcat
    21001 tagaagtaac tgtaatataa aacacaaaaa taaaaaagag gggattgatt ttatatgata
    21061 tttaaaggtt ctgctgttgc tctagttaca ccatttacaa aggataacaa agttgatttt
    21121 gacaaattag gtgaattagt tgaataccaa atagctaatg gtactgatgc tatagtatct
    21181 tgtggtacta ctggtgaagc taatactatg actgatgaag aacaacttgc tactattaag
    21241 tatgttgttg aaaaagttaa taaaagagtt cctgttatag ctggaagtgg ttctaatgat
    21301 actatgcact cagttaactt aagtcaagaa gctgaaaaat taggagtaga tgctctatta
    21361 ataataacac cttattacaa taaagctaat aaagctggac ttaagcgtca ttttgaaaca
    21421 atagctaaca gtgttaaact tccaattata ctttacaatg tccctggaag aacttgtgta
    21481 aatataagtc ctagccttat agttgaactt gctaaaattg ataacatagt tgctgtaaaa
    21541 gaagctagtg gagacctagg acaggttgca gaaatagcta gtttagttcc agatgacttt
    21601 gctatctact ctggtaatga tgatactata cttcctttat tatctttagg aggtcaagga
    21661 gttatatcag tacttgctaa tgtttgccct caagaaactc acgatttggt agctaaattc
    21721 tttgaaggcg atattgaagg ttctagaaaa ttacaacttg gtatggatgc tctaatcgca
    21781 gctttattta tagaagtaaa tcctatacca gttaagactg caatgaattt attgggattc
    21841 aatgttggag atttaagatt acctctagca gaaatggacc cagcaaattt agaagtgtta
    21901 aagaaagaat tagttaactt tggactaaaa gttaatgcat agtaaagatt aatgcatggt
    21961 aaaaagtaag tttggtcaaa agttagccct taatcatagg aggaaattat gttaaaagtt
    22021 atagcaactg gttatgatgg aaaaatgggt aagattttag ccgatactat aagagaagat
    22081 aatgaattag aattggtttg tgttgcagct agaggtctgg atagctatga aggcgacctt
    22141 aaaatttatg aagatatgag tactatagtt gaggaagctg atgtagttat agatttttct
    22201 catcactcta atttagataa tatcttatct tacgttttaa agactaaaac acctttagta
    22261 attgctacta ctggatataa tgatgacgaa atgaacaaaa taagtgaagc ggctaaagtt
    22321 attcctgtat tccaatcata taatatgtct cttggtgtaa atgtattagt aaaattggtt
    22381 aaagatgcag ctaaattact agaaggattt gatatagaaa taatagaaaa acatcacaac
    22441 agaaaagtag atgccccaag tggcacagct gttatgattg ctaacgctat aaaagaggtt
    22501 ttgccaaacg ttgaaaataa ttatggtaga tatggtcgta gtgcaaaaag acaaccaaat
    22561 gaagttggta ttcatgctat aagaggtgga aatattgttg gcgaacatga tgctctattt
    22621 gctggagaca atgaggttct tacaataagc catcaagctc aatctcgtgg tatctttgca
    22681 agtggttcta tagctgctgc caaatactta gttaagcaaa aaccaggatt ttataatatg
    22741 gacagcatgt tgggataata gtataaatat aataatacac aatataaatt aaacatatac
    22801 aatatatata taataatacg caatacaaat caaacatata taataaattt atttaatact
    22861 atgtctatac aataaaagct aactaaaata aaatataaat aataagaagt aagtatatac
    22921 taaaattgac aaataagtat ataataaaag aaatataatg aaatacaagg agaattaaca
    22981 aatggtaaat ttaaacgatg cttatgaaat agcaaggtat ataaaagaag ttaaaaagaa
    23041 aacacctgtt aaggtatatg taaatactaa ctctttacac tttcaatcaa ctgataaatt
    23101 taaggtattt ggaagtaatg gttcttatat atttgtaggt gactatgagg atataatgga
    23161 agtattagat aaacatggaa atgatataac agatactcat gtagaatatg atagaagaaa
    23221 ttctgctatt cctctaaaaa atactttaag tgaacatgca agaattgagc caggtgcaat
    23281 aataagagac atggttacta tagaaaaaaa tgctgttgta atgatgggag ctgttataaa
    23341 tataggagct gttattggtg aaggttctat ggtagatatg aatgctgtta ttggagctag
    23401 aggaactctt ggtaaaaatg ttcacttagg tgctggtgct gttgttgctg gtgttttaga
    23461 gccaccttct gctactcctg ttatagttga agatgatgtt ttaataggag ctaatgcagt
    23521 tattcttgaa ggtgttagaa tcggtaaagg tgctgttgtt gcagctggtg ctgttgtaac
    23581 tactgatgta gaagctggtg ccgttgttgc tggttctcct gctaaagtta taaaaatgaa
    23641 agatgaaaaa acggctgaca aaactaagct tatggaagac cttagaaatt tagattaatt
    23701 aaatagtact atactattaa ttaaacaata atatactaat ttaaaaaatt aattaaaaag
    23761 gtgtctctgt gtgaatttaa ttcaccagag gcaccctctt ttttacaata tttttatctt
    23821 ttatttataa tcattttatt tttttacaat tctcttattc attcttatat catttttatt
    23881 tcttgctgac aagtattttt atttccttca atttttcaat atatcaatgt aataaactat
    23941 taaacttttt ataatttaat aaagtgaaaa ccattaatct ttctataatt taataaaatg
    24001 aactactaaa ttttctatat atcaatagaa taaattatta aactttttat aattcaataa
    24061 agcaaaccat taatctttct ataatttaat aaaatgaact actaaatttt ctatatatca
    24121 ataaaataaa ctattaaact ttttataatt taataaatag aactgctgtt taccactggt
    24181 tgtgcatctt tattgccaca aagcacaact aacagattac ttaccatagc tgctttacgt
    24241 tcttcgccca aagtcacaac attattttca cttaaattag tcaatgccat ctctaccata
    24301 cttacagccc cctcaacaat ctttttacgt gctgctatta tagcctctgc ttgttgacgt
    24361 tgtaacattg ctgctgcaat ctctggtgca taagaaagat gagtaattct cacttcacac
    24421 acttcaattc ctgcaatatc aacccttgat tgtaattcat cttttaatct atctgctatt
    24481 tcctgactac taccacgaag agatttttca tctccatctt cagatacatc atatggataa
    24541 agtcttgaaa cattacgaat agtagaatca cactgaatag ataagaatgt attataatta
    24601 tccacattaa atactgcctt tgttgcatct ataaccttcc aaattacaac cactcctatt
    24661 ataattggat ttcccaataa atcattgact ttctgctttt cattgttaag agtcattgtt
    24721 tttaaagata cttttttgcc ccttgaatta gttgatatat ctaccttttc atcagatgaa
    24781 gatttcgata cattaattct tgatgctgct gggtttattg ctgaacaaaa tggattcacc
    24841 caatagtacc cttctttttt tatagttcca taatagttac caaacaaaac tagaactata
    24901 gcttctttag gattaatcat tttcagccca aaaaatagga taaaatctac tactataaat
    24961 acaagtccca aaattaacat aagtgaacct attccagtaa atccactatc aagttttact
    25021 atcccaaaaa ccatgatacc tattgaaact gctaaaaata atacaatcat tatcaaagct
    25081 gctactccat tgaatacttt tgcgtctttc tcttgataag ttttttcttc ttttaacata
    25141 tctatcactc ccatctcagt atattaagtt aagatatctc taatttaata ataacacttt
    25201 taacaattaa attgttgaat ttaaaattaa tactatatgt ttatatattt tttatacatc
    25261 tttatgcata catgtattta gttattttaa tgtattaata ttgatttcca aataaatcat
    25321 atgatatatg aatatggtat ttcaaaatta actttttagt tcatgaggca ctctttttgg
    25381 tataaagtca aatatatttt tatcatttat acaatgaaaa agaaatttat ctatattttg
    25441 aaaaatccac ttaaattttt taatgtaaga taaattgtaa gcttattatc actaatatta
    25501 ttttatataa attatattag tgataaaata aacttataga aatataacaa atttttatta
    25561 atttcatagg aggaatttat gttgaaagtt ataattagtg gctataatgg aacaatggga
    25621 agagttttag cagaatgtgt aaaaaaagat aatgaattag agttggtttg tggtgtagct
    25681 aggtctgctg atgaaaaagg tcatcatagt gatacaaagc tttacaaaac aatgactgat
    25741 gtaactgaaa aaactgatgt cataatagac ttttcacatc atgagacttt agagccaata
    25801 ttgtcatatg ctctaaaaaa taatacacct gtagtattag ctactactgg atatgatgaa
    25861 aatgacttaa ataaaataga agaagcatca aaaaacattc ctatattatt atcatcaaat
    25921 acatctcttg gagtgaatat attaataaaa ttagttaagg atgcttcaaa gatattagaa
    25981 ggttttgata ttgaaatcat agaaaaacat cacaatagaa aagaagatgc ccctagtgga
    26041 actgctacta tgatagctaa tgcaattaga gaagtcttgc ctgaaagtga aaatacacat
    26101 ggtagatatg gtagagattg taaaagaaaa ccaaatgaaa ttggaataca ctctataaga
    26161 ggtggcaata taatcagcga ccatgatgtt atatttgcag gtgataatga agttcttaca
    26221 ttaagccatc attctcaatc tgatgaagta tttgcaaacg gttctatagt tgcagctaaa
    26281 tttttaattg gtaagcaatc tgggctttat aaaatgtcag atatattagg ataagttttg
    26341 tacataataa atctcaatct atttaggtat tcatattcat caatttgaat atctaattga
    26401 ttgagatttc tattctaaaa gtttataaat tttatgctta ccttttaaat ataatcattt
    26461 ttcttaaaga ttatcttatt tattggtata tggaattata ttgtttatta ttttataatc
    26521 tcttcatcat ataaacctat taaatattat cctatttatt ggtatatgga atcatattgt
    26581 ttattatttt ataatctttt catcatataa acctattaaa tattatccta atttattggt
    26641 atatgaaatc atattgttta ttattttata gtcttttcat catataaacc tattaaatat
    26701 tattctattt attggtatat gaaatcatat tgtttattat tttataatct tttcatcata
    26761 taaactattg tattctataa actgatacat atccagctgc agaagtacct gtcgtgcctg
    26821 aaccaaatgt aaaacttaaa gtaacagctg ctgctctagc atcaactaaa aagcttaaac
    26881 ttacacttac atctgatgaa gtaagtgtat ttactgcttt tgcaataaag ttattttgag
    26941 ctactccatt aaagttagta gtaattgaca taaatcctgc aagtgaaagt gtggcacgta
    27001 taccgaaaga tacattgtat atccctccaa ctgcaagatt tatagtacta cttgttggaa
    27061 aagttatatt agttccattt ataaatgatg aattaaatgt cactaatgta ttatttacta
    27121 aacttgaaga ggacactgta aattgtgcat tgtttgttgc taacactcct gttgctcctg
    27181 tcgcccctgt tggacctgtt gctccatttg ctcctgttgc tcctgtcgcc cctgttgctc
    27241 ctgtcgctcc atttgctcca gttgggcctg ttggtcctat cgctcctgct actccatttg
    27301 ctcccgttgc tcctactgct cctgttgggc ctgttgctcc atttgcccct gttgctcctg
    27361 tcgctcctgt tgctcctgct actccatttg ctccggttgg acctgttgga cctattggac
    27421 ctgctactcc attcgctccg gttgctccta ctgctcccgt tgggcctgtt gctccatttg
    27481 cccctgttgc tcctgtcgct cctgttggac ctactgctcc atctgctccc gttgggcctg
    27541 ttgctcctac tgctccggtt ggacctattg ccccagctac tcctgttgct cctgtcgctc
    27601 ctgttggacc taccaaacca tttgctccgg ttgctccggt tgggcctgtt gggcctacca
    27661 aaccatttgc tccggttgct ccagttgggc ctgttgggcc tgttggacct accaaaccat
    27721 ctggacctgt tgctcctact gctcctgttg gacctacctc tccatctgct ccggttggac
    27781 ctgttgctcc tattgggcct gttgccccag ttgttccggt tgctccagtc gctcctatac
    27841 ttccggttgg acctgttgct cctgtatttc ctgttggtcc tgtagcacct gttactccat
    27901 ttgctccggt tgctcctgta tttcctgttg gacctgttat tccatttgct ccggttgctc
    27961 cggttgctcc tgttagtccg gttggacctg ttgctccagt tgctcctgta ttccctgttg
    28021 gacctgttat tccatttgct ccagtcgctc ctgtatttcc tgttggtcct gtagagcctg
    28081 ttattccatt tgctccggtt gctcctttgt ttcctgttgg acctgttatt ccatttgctc
    28141 cggttgctcc tgtattccct gtcggacctg ttattccatt cgctccagtc gctcctgtat
    28201 ttcctgttgg tcctgtagag cctgttgttc catttggtcc agtcgctccc atatttcctg
    28261 ttggaccagt tattccattc gctccagttg ctcccgtatt tcctgttgga cctgttattc
    28321 catttgctcc ggtcgctcca gttgcacctc taggccctgt cggtcctgtt ggaccagtag
    28381 cacctgttgg ccctgttgga cctacatctt gatataaact tggacctgaa atatcactca
    28441 tataattaat cctccttttt taaagttaga gtattactct ataaatattg agtattactc
    28501 tatataatta tatgaatcga caatttctta tgtgataatg tatctatttg cttatatcaa
    28561 catatatgct ttgattctta aatttcatta cttttttgta aaatctttta caattattag
    28621 tactctttta caattattaa tacaattaaa aaactcattt cccatcaatt atttaaaatt
    28681 tttttattat gttataaaaa atagataatt aaattgcata aaattaattt aatactactt
    28741 taattacttt ttaaataaaa aaacctcaac acgattaata aaaatcatat taaggcatcc
    28801 acaaaattat ataattgctt atctatcttc atcagtaaca ttgaatatat aaggaacatt
    28861 tctataataa tcaccaaaat caaacccata tccaaccaca aacttatctt ctatttcaaa
    28921 tccacaataa tctggcacta aatcgacttt tcttctgctt ggtttatcca aaagaacaca
    28981 gcattttaaa ctagcaggat ttttagcttt tagatgtttt aacacaaaat ccatagtaag
    29041 tgcagaatca gtaatatcgt ctacaaccaa aacatcatat cctgctatat cagtagtcac
    29101 atctgaaact actttaaccc ttccagtact ttcttcattg tttccataac tagatgtagt
    29161 cataaaatta actctaagtg gtaaatttat atttctaact aagtctgcac aaaatataaa
    29221 gctacctttt aatagagaaa ctaccataag atttttatct ttataatctt tttctataat
    29281 tgctcctaat tcccttaatt tatctttaat tttttcttct gaatacaata cttcccattt
    29341 ttttgtttct atatccataa aaagacctcc aattgtaata atccttctta attttataag
    29401 agattgctca ctttttcaat actcttattc aatattagtc aatattattg agtttttatg
    29461 ttcattcaac aattattaac aatgtatctt atattttaag tagttcatat atccacacta
    29521 aattacatac tatatatttt agacaaaaaa agaaaaaact tgcactaaca agttttttct
    29581 attatacata aatttataca taatcatatt ttattagagg gtactaatta aatttattta
    29641 tgctattttt gttatacctc ataatacaaa acatattata aagtactagt caactttatt
    29701 catatcattc attacattta agattatctc atctgttata gacatacctt tgtcacttac
    29761 tctacctaag ttttgtatac tttgctcaac acttgaacca actataccat ttagtggtgg
    29821 tacaaaacaa tcttgcttag ctattatagc actttgtata gctgcagatg ctgcagaaga
    29881 taattttaat gcacaaccag ctttcgcacc gtcacatatc attccactta agtcagctat
    29941 catattttct atagctcctt ctatttgctt ttcagtacca ttcataagcc aagagatacc
    30001 agcagttgct ccagtagaag cagcaacacc acatccacat acagcagata atcttcctgt
    30061 atagttctta atataaccag ttactagatg agatatagct aaagcttttg ctagtctttc
    30121 atcagattgt gggaattttt tattataagc aacgattgga agaattgctg ttaatccatg
    30181 atttccactt ccatttgaac tcataacagg catttttacc cctgccattc ttgcatctga
    30241 agctccagca gttaacatca ttgcataatt tataacatca ttacctaaaa gaccttcttc
    30301 tatagacttt ttaattccat acccgacacc aataccagtt ttttgtttta atccatattc
    30361 agccatctct tcattcattt ttactccatc tagtaaaaat tctatatctt taaaatcaat
    30421 ttcttctaca ttttttatta attcttgtat agttactgta tccattaaac tttcagcttt
    30481 ttctgccgca tcatttgaag ctgatacttt tggttcattg tctaataata cttctccatc
    30541 tttttctaag aacgtaaaat tatcatgttt agttcttatt ctcactttag caatatgatt
    30601 ttttcctttt aacacaactt ctataaatac tttctctctt gtatcagcag gtgttattga
    30661 tagtggagta ttatccatat aatcctcagc tattttaact tcctcttttg ttagagtttc
    30721 taacacactt aatccatttt cagaatgtcc acctactata cctagagctg ctgcaatttt
    30781 taatcctaat ctttcagtac ctggtatacc tacgcacata ccatttttat aaatactagg
    30841 actaactaac atacgatttt caactatttc ttctcctaat aattcctttg cctttgcaca
    30901 tgctagagct aaggctactg gttcagtaca ccctactgct ggtttaactt ctgcctttaa
    30961 catttccact aattcttttc ttatatctct cattatatat aaacctccca attaagttta
    31021 gatttagtac tcaaataatt aattaaataa tttcttatct atatttatag caaaatacat
    31081 gccatatttt ttatatcttt ttatattttt agtcttatat tctataacca ttggtatgac
    31141 tgcctctatt tatgtatttt ttttatttgt atagagtatt tatattcttt aaaatggaga
    31201 aacatatgac aatttcgcaa aaagacaaaa aaaagtctca aaatgagatt ctatatcatt
    31261 ttgagacggc tcaaatatat tattttttaa cttataaaaa ccatttttta attcataaaa
    31321 aaagattctg caaaacactt atagtataag tttaaagctt tctttaaagt tatgaattta
    31381 gaaaaattta aattttatat agctttttat tatattacta tgaaattata ttgtattttt
    31441 caatttttct atataatgta gctcttgata ttccaagtgc tttagctgtt aattctttat
    31501 cttttttata atctttgtac ttatttaaag cttttattat ctcaatcttc tctagttcat
    31561 caagtggaat tatcctatcg cttttaactt ctaactcttc tacagaggta ttcttaattt
    31621 tttgaggaat tacattcatt gtgattattg aagaagaaga catattcaca ctatattcaa
    31681 taatattctg caactctctt atattccctg gccacttata ttccatcata gcatcaacaa
    31741 ccctgctatc tatgtcaata acatttttat ctaatttttt tgaatactct ttaaccatat
    31801 gcttgattat aagtgggata tcttcttttc tctctcttaa gcttggtaat tttataggta
    31861 taacatttaa tctataatat aaatcttctc taaaagtgcc attttgaacc attctttcta
    31921 aatctttatt tgtagcagca ataattctta catctattga aacatttgat ttacttccaa
    31981 ttttattaag ttccttttct tgtaatactc tcaataactt tgactgtaaa tgcaaactca
    32041 tatctcctat ttcatctaaa aatatacttc ccttatgagc tacttcaaac attccaagct
    32101 ttccaccttt tttagctcca gtaaaagctc cctcttcata tccaaataat tcactctcta
    32161 ataaattatc cggtatagca gcacagttta cagctataaa aggattatct accctattgc
    32221 tatggttgtg tatggctctt gcaaatagct ccttacctgt tccactttcc ccagtaataa
    32281 gtactgttga tgttgattta gaagctatta aggcttcctt tttagaattt cttatagcta
    32341 cactttctcc aattatgttt tccaatttta ttctataatc tttattcatc ttattgtagt
    32401 tttttatagc atctctttta tctataaagt caataacata tccctttaac tcatttttta
    32461 atactatttt attgatgttg tatattccct tcgaatcata tccgtatctt ttataaaaaa
    32521 aactacagga tttgtccttc ttaaagttat ttatagaagg tttctttata aaatctaatt
    32581 cgacaaatat gtttttgcca gttatactat cttttatatt gaaaagctct ttaaattttg
    32641 aattatattt atcaattttt ccatccacat caatagacac aacagctttg tccatattgt
    32701 ttaatagtgt ctctaatttt ttcttttcta attcaagctc ataagtttta atttgtgctt
    32761 ttaatttatt agatattagg tctgccattt tgcctaaaaa gtttataaga ccacttttat
    32821 tgttttctat aatttgtgct tgttcttttg taaaggctat aaggcctata acaccatgag
    32881 aatcgccatc acatataata ggacaacaca cctctgcaaa ctctacacaa gccccacttt
    32941 tatagcattc cctacatata tcactactct ttgggtcatc aattagtatt gtaatctgtt
    33001 ctgtaagtga ttttttaaaa gccgtatatt tatctacttt ctcacctatt ttgtctatat
    33061 atactcctgt acctgcaatc ctaaataact ccttatttac tatagttaca tctatattga
    33121 gtactgatac tatagcttca gctatatttt gaatatcaga ttttatatat tctaaaccta
    33181 tcataatcat cattccttat ttttctttag cataagtatt tgtcttattt ctttaagaat
    33241 caagtatatc ttatttaaag taaattggat tgacatcagg attacaaaga gcataacaat
    33301 tattattaac tcataattta tttccatcta aacatctcct tataacaaaa gactaggctt
    33361 aacctagtct tttatattat atccatattt atattttaac tcatttatct tctttttccc
    33421 acataaatat attttaattt atttgactct ttaatcatac catcaaagtt taatcttgaa
    33481 aatatattaa atacttcatg tggatagtga atctttgcaa cagaaccaca aaatttatgt
    33541 ttaagatagt ttaacttaac ttttaaattt tttaaattta aatcctctaa tataacctct
    33601 ccattgccct ttaacactct ttgtatttca gatgaagctt tttcacaatc tgtaataaca
    33661 ttaaattggt caactattat tatcttgttg aactgattat catcaaatgg tagaaactct
    33721 aacttacctt taactacatt gcaattttca ttatacacta gagaataaca gacatcttca
    33781 taattactat tctccagtat agttacagaa gttccaagac ctctcaatct cttgcctagg
    33841 tttcctatat gaccaacaag caatatttta tcacctacat tatactcaat tgtatccaaa
    33901 aaacattcta attcatcaga tgtatattta gctttaaccg gctgtttatt tatctgacat
    33961 aatatgcttt tcacaatgct tcacctcttc atttcctcaa ttataaatta tgtacagatt
    34021 acattataat aaatggcgag caactattca agagatattt cattagtatt tttttaaaca
    34081 atctttatac attttaatat gatattatac caaatttatt aggattttat tcataaaaat
    34141 cagtctattt tttatgttta ttcattgtta ttttcatcca atttttttat tttcgatatg
    34201 gatacttcat atgccatttt tttgaccaca ttattttcat ctattttttt ctcatattct
    34261 ctactttgaa ccctacccca aagctgtatt ctatcaccaa cctttagatt ctttgcaaat
    34321 ttagcatttc taccccaaac tattgatggt atataatcag atttattata aggtctgttt
    34381 atagcaacta ataaatcggt tatttccctt cctaaaggtg tcttcctata cacaggttcc
    34441 ttacatacat atccatctaa aaatatacta ttagggtctt tattttcctc gtctatgctt
    34501 tttatttctc tgacaaacac tgtaagcact aatctatttt tattatttaa tgttttgtta
    34561 tatgatctta attggcctac gacattgact aaattttgtt tatcaaggtc aatatcttgg
    34621 agaagtcttt ctgatacagt cattggaagt atatcaaaag aatcgcttag tctgtttatc
    34681 tttattttca tattataaaa tttttctcca aatatctcat ggctaaattc tagcttattg
    34741 tctaactccc ctcttaagtt tactacgtta ttctcatctt taacagctat catattttat
    34801 ccctccacaa ttgttaattc ttatatttct ggtatcagct tatataataa atatatttat
    34861 aagggatgta ttttattaca aatctttgat tgctgtttaa aagtttttat ttagttataa
    34921 atttcattta atatttcact tttataatta taaaattatt atctttttgt accacatata
    34981 ctaattaaac tacctatttc agttttatat taattataaa aatcctatta tatagttaat
    35041 aagtcatat
//
LOCUS       DAEQAF010000036        34881 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.037, whole genome shotgun sequence.
ACCESSION   DAEQAF010000036 DAEQAF010000000
VERSION     DAEQAF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34881
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.037"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(441..2828)
                     /gene="cadA"
                     /locus_tag="KRN00_001809"
     CDS             complement(441..2828)
                     /gene="cadA"
                     /locus_tag="KRN00_001809"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBH1827675.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEVDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALAIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2851..3216)
                     /locus_tag="KRN00_001810"
     CDS             complement(2851..3216)
                     /locus_tag="KRN00_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1827676.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3415..4260
                     /locus_tag="KRN00_001811"
     CDS             3415..4260
                     /locus_tag="KRN00_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827677.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCNQ
                     NMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEEF
                     DEEEM"
     gene            complement(4697..5785)
                     /locus_tag="KRN00_001812"
     CDS             complement(4697..5785)
                     /locus_tag="KRN00_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827678.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5910..6638
                     /locus_tag="KRN00_001813"
     CDS             5910..6638
                     /locus_tag="KRN00_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH1827679.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6840..7331)
                     /locus_tag="KRN00_001814"
     CDS             complement(6840..7331)
                     /locus_tag="KRN00_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827680.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7342..7785)
                     /locus_tag="KRN00_001815"
     CDS             complement(7342..7785)
                     /locus_tag="KRN00_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827681.1"
                     /translation="MYSNTYNNENFMRARAFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7775..8614)
                     /locus_tag="KRN00_001816"
     CDS             complement(7775..8614)
                     /locus_tag="KRN00_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827682.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8833..10218)
                     /locus_tag="KRN00_001817"
     CDS             complement(8833..10218)
                     /locus_tag="KRN00_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1827683.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KEYLKKYGFSIDELEGMDTAFAASYGEGRPVIAVLGEYDALDGLSQKVSTIKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10391..11134)
                     /locus_tag="KRN00_001818"
     CDS             complement(10391..11134)
                     /locus_tag="KRN00_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBH1827684.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IESEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11154..12416)
                     /locus_tag="KRN00_001819"
     CDS             complement(11154..12416)
                     /locus_tag="KRN00_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1827685.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIGGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12600..13598)
                     /locus_tag="KRN00_001820"
     CDS             complement(12600..13598)
                     /locus_tag="KRN00_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBH1827686.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13582..15093)
                     /locus_tag="KRN00_001821"
     CDS             complement(13582..15093)
                     /locus_tag="KRN00_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBH1827687.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVESLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKDILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15147..16109)
                     /locus_tag="KRN00_001822"
     CDS             complement(15147..16109)
                     /locus_tag="KRN00_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH1827688.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGRKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16157..17047)
                     /gene="rbsK"
                     /locus_tag="KRN00_001823"
     CDS             complement(16157..17047)
                     /gene="rbsK"
                     /locus_tag="KRN00_001823"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBH1827689.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17089..18102)
                     /locus_tag="KRN00_001824"
     CDS             complement(17089..18102)
                     /locus_tag="KRN00_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1827690.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDVSVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18331..19308)
                     /gene="bioB"
                     /locus_tag="KRN00_001825"
     CDS             complement(18331..19308)
                     /gene="bioB"
                     /locus_tag="KRN00_001825"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBH1827691.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSHYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEL"
     gene            complement(19514..19777)
                     /locus_tag="KRN00_001826"
     CDS             complement(19514..19777)
                     /locus_tag="KRN00_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827692.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19847..20920)
                     /locus_tag="KRN00_001827"
     CDS             complement(19847..20920)
                     /locus_tag="KRN00_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH1827693.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21389..22147)
                     /locus_tag="KRN00_001828"
     CDS             complement(21389..22147)
                     /locus_tag="KRN00_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1827694.1"
                     /translation="MREYIAFTKKEFKENIRNYKLLSLTILFLVFGIMSPLSAKFMPD
                     LIAHFAPTLKVTTAPTALDSWTQFSGNISGLGTSLTLIVFCNILSNEYSKGTLVIMLT
                     KGLSRSSVVLSKFSIAVIIMTIGFWLSFLCTYGYTMYFWPTANLNHIIFSAFNLWLIS
                     IMYISILILGCVLFRPAFASVLLVLVATVILSLISIPKQIAPYTPNFILSKNIDLVSG
                     KVTPPEFIIPIIVTIVISIVCLLLAVVLFNKKAV"
     gene            complement(22144..23061)
                     /locus_tag="KRN00_001829"
     CDS             complement(22144..23061)
                     /locus_tag="KRN00_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827695.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(23061..23261)
                     /locus_tag="KRN00_001830"
     CDS             complement(23061..23261)
                     /locus_tag="KRN00_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBH1827696.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23266..24360)
                     /locus_tag="KRN00_001831"
     CDS             complement(23266..24360)
                     /locus_tag="KRN00_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827697.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24870..25010)
                     /locus_tag="KRN00_001832"
     CDS             complement(24870..25010)
                     /locus_tag="KRN00_001832"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBH1827698.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            complement(25320..26627)
                     /locus_tag="KRN00_001833"
     CDS             complement(25320..26627)
                     /locus_tag="KRN00_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1827699.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVSGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26692..27171)
                     /locus_tag="KRN00_001834"
     CDS             complement(26692..27171)
                     /locus_tag="KRN00_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBH1827700.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(27218..28081)
                     /locus_tag="KRN00_001835"
     CDS             complement(27218..28081)
                     /locus_tag="KRN00_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1827701.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(28081..28836)
                     /locus_tag="KRN00_001836"
     CDS             complement(28081..28836)
                     /locus_tag="KRN00_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1827702.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28863..29351)
                     /locus_tag="KRN00_001837"
     CDS             complement(28863..29351)
                     /locus_tag="KRN00_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1827703.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29369..29770)
                     /locus_tag="KRN00_001838"
     CDS             complement(29369..29770)
                     /locus_tag="KRN00_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBH1827704.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29773..30270)
                     /locus_tag="KRN00_001839"
     CDS             complement(29773..30270)
                     /locus_tag="KRN00_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1827705.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30294..30698)
                     /locus_tag="KRN00_001840"
     CDS             complement(30294..30698)
                     /locus_tag="KRN00_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1827706.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30928..33495)
                     /locus_tag="KRN00_001841"
     CDS             complement(30928..33495)
                     /locus_tag="KRN00_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827707.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33661..34404
                     /locus_tag="KRN00_001842"
     CDS             33661..34404
                     /locus_tag="KRN00_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH1827708.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHRWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DKLIMNYPKKLINHFHQKDKLLDVDYTNI"
BASE COUNT        11308 a         6384 c         3578 g        13611 t
ORIGIN      
        1 cttaaaaata attcgtcaat acttttttaa attatttttt aaaaatattt actttcttat
       61 attacataat ttattgaatg gcagtcatac tgttggttta gagtatttta acacacacat
      121 tttgttgtaa aaattacaac tattaatata atatatatac aatcataagt attataattt
      181 ttatgaatct aatttaaact taatataaac ttattaataa accttctatg tctaaatttt
      241 aaaattacaa tataaaagct ctacactaaa taaatacatt aaataaacat aatggataat
      301 gagtataaat ttatatatgc aaagcgctcc aataaaaagg taccaataaa gttaaaagaa
      361 acttattgat acctttcatt attacatact tcaatatata attataagtt ttttaaatag
      421 tatggattta catttatccc ttatctcata gctctcatag catttactac tgctataagt
      481 gccacaccta catcagcaaa tatagcttcc cacatagtag ctactcctcc agcacctagt
      541 atcataacta taatttttac tcctagagca aatattatgt tttgccacac tatcttatta
      601 gtcttgtttg ctatttcaat tgctttagat atcttgctag gctcatctgt cataagcact
      661 acatctgcag cttcaatagc agcatctgaa cctaagcctc ccatagctat accaacatca
      721 gcacgagcta atactggagc atcatttatt ccatcaccta caaacgctat tttctctttt
      781 tcagttcttc cttcatataa atcttctaat ctatctacct tttcattagg aagtaaattt
      841 gagtaaactg tatccaattc taattcttga gcaatatttt ttgctacttt ctcattatct
      901 cccgttaaca ttacaacttc ttttacccct atttctttta agcttcttat ggcattttta
      961 ctatcttctt ttacttcatc agagataact atataacctc tatatacttt atcaacagca
     1021 atatagacta ctgtgcctac ttctttagct gatgaataag atatattttc ttttttcata
     1081 agtttctcat tacctgctaa tataaaattg ccattatgct ttactctaat tccataagct
     1141 gctatttcct cataactgtc tattgtatct aaatcaattt ttttattata gtaacttaat
     1201 atggactttg ctattggatg atttgaattt acctccgcaa tagctgcata ttctaataat
     1261 tcttcttctg atataccttc aggatttaac ttagttacat tgaacacacc tttagtaagt
     1321 gttcctgttt tatcaaatac tactgtatct acacttctta aagcttctaa atagttactt
     1381 cctttaataa ggataccatt tttagatgca aacccaattc cactaaagaa actaagtggt
     1441 attgataaaa ctaatgcaca agggcaagaa acgactaaga atatcaatcc tctatataac
     1501 caatcactaa atacctcacc tgagattaca agtggtggca caaatgctat taataaagca
     1561 gctattacta ctattggagt atagtatctt gaaaacttag atataaagtt ttctgtcttt
     1621 gattttttaa tgctagaatt ttcaacaagg tcaagaatct tagaaactgt tgattctcca
     1681 aaactctttg taacttcaat actcaataaa gcatttttat ttataacacc tgataagatt
     1741 tcatctcctt tttcaacttc tctcagcact gactctcctg taagtgcaga agtatctaac
     1801 atagaaactc catctactac tacaccatct aatggtactt tttcaccagg ttttactact
     1861 attatatcac ctacatttac ctcttctggt gacaccacct taacttcaga attaactttt
     1921 agatttgcat agtctggtct tatttgcata agtgaagtta tagactttct ggatttacca
     1981 actgcaacac cttgtaaata ctctcctact ttatagaaaa gcataacccc tactgcttct
     2041 gataactccc ctattgctaa tgctcctact gttgctagag ccatcaaaaa gttctcatca
     2101 aatactcttc cttttgatat atttcttatt gctcttaaaa gcacatcacc acctactatt
     2161 acataggcaa ctataaatac tatattgcta aactgacttt cataacctgt agctgtttga
     2221 tatataccaa atatatatac aagtgctcca attataagtg gaattaattc tttcttattt
     2281 gtatcattta cagctcctga tttttcagta gttctccctt ttactttgtc agtagaccct
     2341 acttgtatat caagccctgg ctctgttgaa tttattattt cttttatttt atttataaca
     2401 tcaacctctt caaagttatt acttatattt actgtaagtt ttttatttac aaagtttaaa
     2461 ttagaagatt caacttcttt taatttagaa actttgttat taatctcttc tgcacaatga
     2521 gcacagttta atcctcctaa tataagctct tttttaattg atgttttact agctgcattt
     2581 tctttagaac ttatttgtat atcaagacct ggctctgttg aatctattat atctattatc
     2641 ttttctatag tagtatcctc attaaaactt tcctttatat ttactgtaag ttttttattt
     2701 ataaaattta aattggaaga tttaacttct tgtagtttag aaactttatt attaatctcc
     2761 tctgcacagt gagcacaatt taatcctcct agtataaatt cttttttaat tgaattattt
     2821 gcttccatat atattcactc ctctcattta tcatttataa gtctctctaa tatgatttaa
     2881 tccacaatca aatatctgac ttatatgact atcatctaat gagtaataca ctgtttttcc
     2941 ttctcttcta aactttacta atctagcctg ctttaatact ctaagttgat gagatattgc
     3001 agaatgagtc atatttaata aactcgctat atcacataca cacatttcat ttgcaaataa
     3061 tgcatataat atctttactc tagtagtatc cccaaatact ttaaataatt ctgctaaatc
     3121 atataacatt tcttcatctg gcatagttga tttagcctct gttactattt cttcatgtac
     3181 tatattacaa ttacaatcat ttatctcttc tctcattttt aatcctccat tattttaata
     3241 tatgaataac tgttcatatg ttcattatat gttatcattt ctaaatttgc aacaataatt
     3301 tttattaatt taatataaat agaatgcaca tattataaac ttttttaata tatatattat
     3361 tagaataagt ttttgtaaac ttttttatag ttttctagga ggtgcaagtt taatatgagt
     3421 aacaagaaaa aaaaggattt agatactagt tacatgcctt acttagaccc agcgaactat
     3481 gcagattata ttactaatga agaaattccc caagatgaat tgagaaatga ccctcaaatt
     3541 tctaatggtt atacaaaaat acctaataac cagaacataa ataacctata tcctaataat
     3601 gtaaatcatt atcctaaaag tagtaattct ccaaacaact tgcctaacac aaataataca
     3661 tccggaaata tgaattacaa tacatctgct acaaataata tgcctaataa catgaataat
     3721 aatacgggta tgcctaataa tatgtctaac aatatgaata gtaatatggg tatgcctaac
     3781 aatatgccta ataacatgaa tagtaacatg ggtatgccta acaatatgcc taataatatg
     3841 aatagtaaca tgggtatgcc taacaatgtg cctaataaca tgaatagtaa tatgggtatg
     3901 cctaacaata tgtctaataa tatgaatagt aatatgggta tgcctaacaa catgtctggt
     3961 aatatgaata atatgtatgg taatacaggt atgcctaata acatgaacag caatatgggg
     4021 tataatatga acaatactat gggtattcct aacttctcat gtaatcaaaa tatgcctcct
     4081 aatgtactta tgatgatacc aggagttata tgtcataata caatgcaagg tatgcctgta
     4141 gttatgccta gtactatgcc tcctaatata tatcctactc cttatggttc tagtaatatg
     4201 tctgtacaag gtataccaca ggctactaat attgaagaat ttgatgagga agaaatgtaa
     4261 tatatatttt tttaagtaag ttgtataaaa cattaataat tgaccataat aataaatgta
     4321 ttcctcataa tattccccca atattattat aggtatagaa agttgactga atatgcgctt
     4381 attcggtcaa cagatattaa cataatctaa taagataaac atagaaaaag tcagataaaa
     4441 tttaatttta tctgactttt tcatttaaaa atgctctctt gtgttggtga ttcagaatag
     4501 tatggtactc gtatttgaga ctaatattgg caaacaacat aaagaaaaat ataaattttt
     4561 tataataaac tgtataaaat tttaataatt gaccacaata ataaatgtat tcctcataat
     4621 attcccccaa tattatagaa ataaatttaa gcgagattaa attcagttaa tctcgcttaa
     4681 ataatgtcta aatttattat tccaaaaaat catcaaaatc taatgaacct gattctgcaa
     4741 aatcatataa tgcattttgc tcaaagaaaa atttctcttc aaatttaata tagtcgctat
     4801 aattagactg acttatttca ttgatataat tgcaatcatt ttcgttataa gtaccaataa
     4861 aaaacttatt tcccattaag taatatatcg ctttcatatc attatttatt atatatacat
     4921 tttcttttac atggtcatta ttaaaattaa atctagtaaa aaatatgcct tcattcatat
     4981 tactttttaa cagaaatgga ttttctctat aaaatactcc tgcaaattct tcaggtgaat
     5041 ttacactgta aacacttaca aattcacttt tagaaatctc atcaaatacc tcaaaatcat
     5101 acataggttc tttatctgtc actaatagag aattaattct aaaaccagtt tcataacact
     5161 tacttatgca aaaagcaatt ttacatatat aatatccatc attgtcttca tataaagctt
     5221 cacttatata tctgccttga cctttatcac ttaccacgtt tttaagtaat gttccattta
     5281 tattagtaat atgcatattt gcaatctcgt cacttccaga aaaatacttt aaactttctc
     5341 tatcccatgc tataaatctc atggtcatat agtttataaa ttcaacttcc tcatcaactc
     5401 ttttacatat tttattgtat aatttttcta tagttaaatc tgttttatag ttttttataa
     5461 tatcaatata ctcacattta tctcctggca atagcttatc ataataaaga ttcttattac
     5521 caaaataaga tactaaaaat aaagattcat ccttcgttaa ttcaactcta tctgaaccaa
     5581 atcctcccat caatctttct tcttccatat aagcttcttc ttgtgttggg ttatttaaac
     5641 tcacataatc cgctaatcct aatccctctg catctaataa aaaatattga caaaagtgat
     5701 tgttttcatc atctatccaa tttattataa gacctaaact gcccataagt ctagaatttg
     5761 tagcctttgc aaaattaaaa ttcatatagt cacatccttt aaactctaaa atacttgttt
     5821 tttaatatat aaattattat acatatattt taacaactta gatacaattt ataatataat
     5881 ataaggaaat gattaattga ggtggtctta tgaaaaatat agcagctttt tttgatatag
     5941 atggtactct ttatagagac tctcttatgg ttgaacattt taaaaaatta attaaatacg
     6001 atataattga ccaaaaaaat tggtataaac atgctagaga cacttttatg gattgggata
     6061 aaagacaagg taattatgat gattatctat tagaaatatg tgacctttat gttgattcac
     6121 taaaaggatt agataaaacc tgtatcaact ttacaagtga ccaagtaatt aaattaaaag
     6181 cagatagagt ttataaatac acacgttcaa ggattgagtg gcatctaaat caaggacaca
     6241 tagttatatt tatatctggt agccctggat ttcttgttga aaaaatggca aaaaaatata
     6301 atgtaaccga ttttctagga agtgattatg tctttgaaaa caatatattt acaggcacag
     6361 ttattccaat gtgggattct ataagtaaga ataatgctat aaacgatttt gttgtaaagt
     6421 atgatttaga tttatcaaac tcgtatgcct atggagatac taatggtgat ataaatatgc
     6481 taaaaagagt tggaaatcca atagcaataa atccaacaaa ggaactttta tctcaaatat
     6541 cacttgatga ggaaatttct aaaaatgttg agataatagt agaaagaaaa gatattattt
     6601 attctctatc tacagatgta aatatagtgg atatttaatt tatactatct attttaaaaa
     6661 cttatattat atctaatatt tatatctaac atataaaagc tttgactaaa aatcaaagct
     6721 tttatatgtt gcactaagaa tatattaaat ttagctttat gctttaatgt atattcagat
     6781 atatcattta cacttatcta aactacaatt tcattaaaat taaatataaa aatcaactat
     6841 tattttttaa atagcatctt tcttaatcta ttattgtaat aacctataaa agaactgtaa
     6901 acatagtcat atactataaa ggctatctca aatgaaccta taataaatat gtttattgga
     6961 atataaacta ttgttcttaa taaaaaatac aatataagta tcattatatt tgcaaatact
     7021 aatttcataa aatactcaat atatatagac ctatcttttt ctataagata ttttacaata
     7081 ccatatattc caaaggtaag tgaatataca atccattgag acttacttgc catcactata
     7141 aatcctaaaa ctatagaacc tatataaaaa gcaattccac tcttaaagcc ccattccatt
     7201 attacaattg atactaaaag tgatgctaac cccataataa acaatgtatt tacaggaata
     7261 atatttgtaa gagtcaacaa tatcacattt aatgctaata aaactcctcc ataagcaact
     7321 tttatactca tatttatcat cctaacaaca agttattaaa tctccaccaa aacattcaca
     7381 acatgaatct aaacaccaaa gcttagcaca attttcacaa caatcgtcac ctagacaaca
     7441 acagcaatca tcacagcaac agcaacaaca tccatctaaa tcattacgtc ttcttctatt
     7501 ataattgtca gccctattgc tataatcatt tctatattgt gtataacttc taagtgcatc
     7561 actatattca ctattttcag gctccataaa ttttgctctt tttaagaagt cttcaccttc
     7621 ttcataatat cctatgttca ttgcagaaaa gccagttaaa taataccact ctgcacattt
     7681 gtcagtcaaa gtttttaaaa aatcatatgc ttttttaaat tcactatttt ctatgaatgc
     7741 tcttgctctc ataaaatttt cattattata agtattactg tacattcttt ccacctctac
     7801 tttctaatat attaatatat cttaaataaa caccagaata aattatattt tctattattc
     7861 caacattttt atttagattt agattatcaa ttcccctagc taaaaaccct aatgatgtta
     7921 ctattatttt ttttactttt tcttttaact catcattttt atcaatatac tctataaatg
     7981 gattatatct tcctttctta aaatcttcat ctaaatcttc ataggcatct agtagatata
     8041 tatacttacc tatattaaaa cctatcattc ttaagtttct ctcattttca tcttttttat
     8101 agacaaatac ttcacccatt atatttccaa atatactaga tacttcatct atatttatat
     8161 ttttatcttt ttctaactta tttaattcat ttagttgttg ttttatatac tctgcttttt
     8221 caggatactt ttcatatgct aattttaatt tgtttttata tatataatat gccaatttat
     8281 cttttatgcg tttatcatcc attaaattat cttccaattt ataatacgtt aaaagaatat
     8341 tcatacttgc tgcatattct gtaatatcat ttgtaattac ctttttcttt ttaaatggat
     8401 ttactataca cacttcctct gtacttatag actctgggtt atatactgct gttaataaaa
     8461 caattaaaaa tgttatatca taattcaaag aaaacctaga gatttctcca tgatttcttt
     8521 ttaagtattt acatagtcca caatagtaag ctttgtaata atcatattct ctaaatgtta
     8581 aatccatttt gtttatttta acatatccaa acataaatac tcctttttgt actatttttt
     8641 atttagatta tatatagtat aacacttttt atcaagatta tataatttac agtattctaa
     8701 gaaacttaaa aaattccttc taatcattgt atcttaaatt taaaataatt agaaggttgg
     8761 gttaaaaata atattaaatt atatacttat attaactcat acaagttggt tatgcttata
     8821 tcaatttaag ttttaaataa ttggtatata tttaaaacta cctacagtat ccttcaattc
     8881 tttttttgct ttatttatca ccaattcatc aagcattaca tcatttattg aacatgatat
     8941 agatttagat gccaataaca ttgctttaaa tcccatatca gaacctgcac ttgcacaaga
     9001 ttgccatgta tgggcagaaa taccaatagg ccaaactgaa caagaacact gtgctgtagg
     9061 aattatgtaa ctaacatctc caatatccaa tgataatgat atacagttat tatgagtaaa
     9121 tgtatcatct gtaacctcat catgtaaatt catcttagta atatccttat ttccacttaa
     9181 tacactagaa acactacttc ttttatctat agacactgtc tcagctaatt tatctgcaaa
     9241 atagtagtca tcttcattat agttttgcac acctactaat ttcatatttt gtgatagaat
     9301 atctgttaat attgtatttg gaatatagtc atatactcca cttataatgt catattccat
     9361 aatagtacca gtcattaatg ctgctccttt tgctatatca acaatcctac caaatacatc
     9421 tcttacatgc tccattttaa ctcctcttat gtaataccac acttctgcaa aatcaggaac
     9481 tatatttggc atttttccac cattagtagt tacatagtgt actctacaat tatcaaatat
     9541 atgttctctc aaataattac aacctatatt cataagttct actgcatcaa gtgcacttct
     9601 tccgttataa ggagcttgtg ctgcatgagc actaatccca ttatatctaa atttcacaga
     9661 gtaattagca agtgttggga ttcttatagg agtatttata tcaaatggat gccaactaaa
     9721 agcacaatca attccatcaa aaaaaccttt ttttatcatc aatacttttc cagataaatc
     9781 ttcttctgct ggacatccat agtattttat agtccctttc agctttttta gtttgattaa
     9841 ttcctttact gcaattacag ctcctattga acctgtaccc agtaagttat gtccacatcc
     9901 atgacctgca ccaccatcta caataggttc tttaatagtg gatacttttt gagacaaacc
     9961 atctaaagca tcatattctc ccaaaactgc tataactggt ctaccttctc catagctagc
    10021 cgcaaatgct gtatccatac cttctaattc atctatacta aaaccatatt tttttaagta
    10081 ttctttttgt aaatttgaag cataatattc tttatactga agttctggat ttttccatat
    10141 cttatctgat atatctctta attctccctg tatctcatct atatattcca tcaaaaactt
    10201 tttatttaaa ttatccatat taattatata aacctccctg tttctaataa cttatcgatt
    10261 atcagccaaa atgactaatt ttaacttatt taaaaatatt ttctatcata caaccatttt
    10321 atacaataaa acctcttgac ttgtaagttt cattttatca agtaagaggt tttcaagttt
    10381 tataaaattt ttagcatgtt aaccaatcaa gcatattaac ccataattta ttatagtatt
    10441 tccaatcagt aaattctttt ggaccccagt gaggtgcaca gtcagaacta aagatagcag
    10501 attttccttt tccaaactcg ccaacagcta caaatgggtc tcctccaata gttgctaaaa
    10561 caggacaatt atctctagct actgttttgt tatatcctaa aaactttggc cattctgttg
    10621 gtataccttt taatactgga tgttcagatt caataacttc tggaattatt cctgctggtt
    10681 tttcaactct atcatcttta tctatcattg ttattggtaa tacatctttg atagcagttt
    10741 ctccaaatct agcttttgca tctattcctg taaatgacat atatccacct accatgatta
    10801 acgccccacc attatttaca tactctttga ttagttcaag tctatctgga ttactattgc
    10861 aatctataaa agtactatta gataataaga acgtattaga acctatatca gataatatta
    10921 tacagtcata ctcatttaac tcttctaatt tatacggaaa actatctgct gctacatgtg
    10981 caggcatatg aactgtctca tatcctccag attctattgc ttctttcaac cactttacag
    11041 cttcttcata atgagttgta acaaacgtat caaatccttt tatatgagtt atatttttta
    11101 cccaagattc ccctactatt aatacttttt tcatttatat attcctccta cttttataag
    11161 tttaatatta gacttgcata cataagtata ctatctaaat actccttaat ttcaacatat
    11221 tcatcaattg aatgacattg ttctattgaa cctggcccta atataagtgt tggtatttca
    11281 gctaaatttt tcattactct cgcatcattg ccagctgttg aaccttttat ctctaatttt
    11341 tttcctagag tttcttctag tattttatgt gcattcacta caaaatcaga atccttgtcc
    11401 atctcaaaac ctaaccctga ttgatatatg tttatatttg gtttattatc tttaagccat
    11461 aaatctccat tagcccttgt cattatgaca tttgttacat catttacaac ttgttcataa
    11521 ctcattatat ttggcaagaa gtgtacacat aaattaaata cacacttatc tggcacagta
    11581 gaacctgctg ttccaccatt tattacacct aaatttattg taggtgaagg taatagtgga
    11641 tgtttatata tcataagcca gttatgttcc aactctttta tatcttgaag caacaacata
    11701 gccttctcaa ttgcatttac accctcccac ttactaccac agtgaagaga cacaccttta
    11761 acctcaactt caaagaatac aaatcccata tgtgcaacta ttaagttttg ttctgatggt
    11821 tcacaaatta tgcaacaatc tccaccaata ccattcataa ctgcatttat ggtaccattt
    11881 ccgccacctt cttcatctac tactgacatt atttttacat tgccaggtac atttagacca
    11941 ctatctttta taagctttac agctaatatt gatgctataa gtccagattt catatcagca
    12001 gttccaagtc cataaagttt tccattatct tctgtagcac gatatggatt atatttccac
    12061 ttacttatat cacccggtgg catagtgtct acatgaccat taaatacaat tgtcttacca
    12121 ggtaaatcat cactatactt acaaattaaa ttatatctat cttgataatt gtgacctaga
    12181 tttccttctt tatatatatt ttttgctttt ttaattaatt cttcgctcat ttcttgtcta
    12241 tctacactaa agcctatgta atttgcaagt ttttcaatat attcctgtcc ttctttttca
    12301 aatccaccta gtattccatg accaacatct tcagtcttta tacttacaag ttcttttaaa
    12361 taatctatgt attcttgttt tttactattt aatgtatcta agagaatttt tttcatattt
    12421 cctcctaaga tttattttta catttaaaat ttcaagtcta atctcatcta tttaagccat
    12481 agtaaacttt ttcacttagc atattcccat tcaatgtata aagatgtatg caaattaaag
    12541 tataaaaata tatacaaaaa cttaataatt tttatagttt ataagctaaa atttaattac
    12601 tatttagatt tagctgattt ttttaatttt atattattta tccatatagc aaataacatt
    12661 accaaacctt ttataatcat ttgattatat gaagatacac ttaataagtt taatccattt
    12721 cctaatattc ctattattcc gacacctata catgtaccta ctatagaacc agaaccaccc
    12781 atcatattag tgccaccaag cacaacggct gctatagcat ccaattctgc tccatctcca
    12841 acagttggtg aacctgatgc caaacgtgat gatagtatta tcccagctaa tgctgttagt
    12901 agtccagcta gtgcgtatac ttttactata actttattta cttttactcc acataatcta
    12961 gcggcctctt catttccacc tactgcatgt acatgacgtc caaaattagt tctttttaat
    13021 agaaaatgtc ctgctattac aactataatc ataattataa ctggtattgg tattggtcca
    13081 atatatcctc taccgagcat cttaaatgca tctgtattta ctgatatagg tcttcctcct
    13141 gtaaatacaa agcttgcccc acttattatc gttaacatgg ctaaagttac aatgaatgga
    13201 ggtagttttt gtgttgaaat aattgcacct tttatgactc ctaatattgt ccctattgct
    13261 aatgcaagta tcatacctac ccatataggt gcattataat tcactactgt tgtagcccaa
    13321 aatgtaccta ctaaagcaat tactgctcct acacttaaat ctattcctcc tgtaattatt
    13381 acaaatgtca tacctactgc aagtattgca tttattgata tttgtcttcc aacattaatt
    13441 aaattatcta aagttaaaaa gttagatgaa gctacactca ttattataaa aattattaca
    13501 agtcctacag ctgcactccc ttggtctcta aatacacttg ttaattttgt caataatgga
    13561 gaagattttt cttctttatg cttagttatt gaactcatta attttacctc cgaaagccaa
    13621 ttttaataca ttattttcaa ccatttcttc accttctaaa aatccactta tatgaccttc
    13681 tctcataacc attattctgt cactcattga tattaattct ggtatttcag aagatatcat
    13741 tattatactt acaccactct ccactaaatc tcccattaga ttgtatatct ctgccttagc
    13801 atttacatct atacctctgg ttggttcatc cataattaat atatctggtt gtaataaaag
    13861 ccatcttgct attatagctt tttgttggtt tccaccactt aaactttgta taacttgatt
    13921 catatgtggt gtttttatct ttaaagcttc tatgtatttt tctaaaatat ctttttcctt
    13981 ttttctatct ataattgatt taaacttaga tatctttttt aacccagcca tagttgtgtt
    14041 ttctttgaca ctcatttgta aaaacaatcc agtacctttt ctatcttctg ttattaatcc
    14101 tagtccattt tctattgcat ctgatggagt tttaaacttt acttcttcat tgtttaaata
    14161 tattttccca gaatcatatg ttctaagtcc aaatatagct tctactattt cacttctctt
    14221 acttccaact agtccaccta ttcccaatat ttcacctttt cttatattaa agctaatatc
    14281 attaaaaaca ttgttcttag ttagactttc cactcgcata atttcttctt ttatttctac
    14341 ttttcttttt gggaaaaatt ggtctagctt tctatctatc attaaattaa ctaattcttc
    14401 ctcagacgat acatctttgg tattcaaagt cgaaatcgtt ttcccatctc gcattatagt
    14461 tattctgtca caaatctcaa agagttcttc catcctatgg gatatatata ttatactaac
    14521 tccactctct tttaaatcat ttataagtct aaaaagtatt tcagtctctt ttttacttat
    14581 tgaagaagta ggttcatcca ttattaatac tttagtttct gatgataaaa ctcttgctat
    14641 ttctaccatt tgtttttgag ctatactaag ctctttgact aaactatttg gatttatatc
    14701 tattcccata ttatcgaaaa tctttttagc ctcttcattc atttttttgt cattggttaa
    14761 gactttgcca tttatttctt ttcccataaa aatattttgt gctactgtta attcgtcaaa
    14821 aactgttagt tcttgatata tggcatttat acctatcttt ttagagatat ccggggatat
    14881 attctctatt tctttgcctt caaaaataaa ttttccagaa gttttcgaat gtgcaccagt
    14941 taaaatcttt atcattgttg atttaccagc accattttca cccagtagtg catgaacttc
    15001 gccatgaaat aactcaaaat taacattatc taatgctctg acaccaggaa attctttagc
    15061 aatattactt aacttcagaa ttatattact cataatgaca ctccttttta aataggattt
    15121 ctttcaaata atctcatttt attttactaa ttcttaaagt cttttatatt ttccttatca
    15181 taaagtaaag ctggtactgg tatattcttt tctacctttt ccccttttat agcttttact
    15241 actgcttcta cagctaaacg tcccatctct ttaggttgtt gttgaatcat agcaagaata
    15301 gttccatctg ttattccact tgatgcttct tcagttaagt caaatcctac aatcttaaca
    15361 tccttatttt ttgcagattc aagtgcagct ttagctccta gtacactatt ttcagctgtt
    15421 gcatatatta tatctacatc tggattagat tgaattaagt tttctactgt attaagagat
    15481 tcttctctgt catatcctgg ttgtgaattt aatatcttaa catttgctga accttttaat
    15541 gcatctttaa atccatctat tctctgcatt tgtatttgag attttaaatc tgtcactatt
    15601 gctatttctg actttctacc taacttttca tctatgtatt ttttagtgta ttcccctaat
    15661 tttttaccag catcataact aactgttcct acataacttg taatattttc agtatttaat
    15721 acagcatcta ctgtaactac tggcattttt tcaaatgctc cttctactgc tggtactata
    15781 gccgaattat cagttccaag tactatcatt ccatctacat tctgttgtat aaaatcttct
    15841 attgctgatg tttgcttagc tacatcttgg tctgggtcat ttactataac tttcacacct
    15901 aattctttag ctttttcttt tattccctca tcaatatcta taaaaaattg atgttgaaga
    15961 gttattgtag atactccaat agttaaatct ttcttgtctg aaccaccttt attatctgat
    16021 ttacttggtc cttccattga acaccctgtt aacattccta ttgctagtat tccagcaatt
    16081 cctaaagata aaatttttct cactctcata attaacctcc atttttaata gttttaaatt
    16141 tgaacaaatt agatttttat ttattattta aatacttttc aacatcttct ttatagggca
    16201 taccagattg tgcacctagt ttagttacag aaagacctga tactactact gcatattcta
    16261 ctgctgtata taaatttttc ccttctgtta tagccactgc caatgctcca ttaaatgtat
    16321 ctcctgctcc tgtggtatct tgaacatcaa cacttataca agatacatgc ttgatttcct
    16381 caccatcata aaatctagct ccattttttc cttctgttat tacaagttta tttggatatt
    16441 tttttaatac ttcttctatc ccttcatttg tgtcaaaaac tatcttatat tcatgttcat
    16501 ttggtgttaa gtaagttact ttttctatta tatcttcatt tagttttact gctggtgctg
    16561 gatttaataa aaccctaatc ctattttcaa aacagaaatt cactacataa tttattgttt
    16621 ttaatggaat ctctaattgt agcaatacta tatctgcatt ctttatctct tcttcattct
    16681 ttttaattaa ttctatatct actagctcat tagtccctgg tacaacaaca atactattat
    16741 cattttcaca taatgttata acagcaacac cagaactttt gtgattattt ctggatacta
    16801 agctataatc aactttattc gttctaaaat ttcttattaa ctcctctcct aagccatctt
    16861 cccctatgca tgatatcatt tttacatttg ctcctagttt agaagctgag atagcttgat
    16921 tagccccttt tcctccaggt gatgtaaaaa aactattacc taatactgtt tctccttttt
    16981 ctggtctttt atctacagaa cataccatgt ccatgtttac acttcctatg acaactatgt
    17041 ttcccattac attactcctt tacatatcta tttatgtctc tcgtgctgtt attcactttc
    17101 ttttgttgaa tctcttatga ccaattctgg tttgaaaatc aattcatcaa acgattcttt
    17161 tttatctcct cttaaacaat ttatcaatat ttcactggct ttatatccta tatcataaga
    17221 cggctgtttt actgtggtaa gagaagggct tattagactt gatgtttgaa tatcatcaaa
    17281 tcccacgaca cttacatcat ttggtatact taatcctctt tctttaagac ctcttatgac
    17341 acctattgca atcaaatcat ttgcacaaaa tattgcatca aaatctatct tttctaaatt
    17401 ttttataaat tcttgtcccc attcaatctt atattttcct tcaaatacat aagcaggatt
    17461 gtagcttaaa ttacactcga ttagagcctt tttatatcct tctaatctat ctactgctat
    17521 ttcattttga agtggaccac ttaggtatat tattttctta tttccaatat ctaataaatg
    17581 ttttgtagct atataggccc cttcaaagtt atttatttta acaattcctt ttaaggtttc
    17641 tttgttcata cttatcttct tatcaatcaa gacagttggt atttttatat ctttataatt
    17701 tgcttctttc cagtttgtat ttgaagatgc tgcaaatata attccatcta tcatcctctc
    17761 tgatagtgtt cttattcctt catattcttt tttagcatct tcatctgtat tacataaaat
    17821 tatattgtag ccttcttcat tagctttgtc ttctacacct cttgatacat ctgtaaagaa
    17881 tggatttcgt atatctggta taagaagccc tatagtatta gtttttttag ttactaaact
    17941 ttgtgctaat ttatttggta cataattttt ttccttcatt attttcaaaa ttttttctct
    18001 tgttgcctga cttatatttt catctttatt attaatgact tttgacacag ttgttttaga
    18061 aacaccagcc aattcgccaa tttcttttat agttatactc aagaagttca cccccaaaat
    18121 ttaggaaacc gttttactta accggttacc tagatactat cacatctttt ttccatttgc
    18181 aaccatttta tataaatttt gatatttttc ccttttttca aaatattgca acttataatt
    18241 caattttaat atttaaatta atctgcaaaa aaaaattaat atacttttat aattatctaa
    18301 aagtatatta attaatttaa gcagtattta ttaaagttca aatccttgct ctataatcat
    18361 ttttttatca ttttcaatcc cacttccaac agttgtcaaa taatcaccaa caattgcaga
    18421 atttactccc ccattaaatc caactttgtc atatcccttt aatgatagcc ttccaccagc
    18481 ataccttatg tacacattag gaattataaa cctaaatact gctgttgttt ttagtatttc
    18541 cattggttct aatacatcat aattttccat tggtgtattc ttaataggat ttaaaatgtt
    18601 tattggaaat gattttacat ttaattctcg tatttcaaaa gccattttta gtctctgttc
    18661 ttcactctca ttcattccaa ttataccacc tacacataca tctagcccag cttttttagc
    18721 atcttttata gtttttatcc tatctttata tgtgtgtgtt gtacatatat tatgaaaatt
    18781 atctctacac gtctcaacat tgtggtgata tgtagtcaca cctgctgact tcaacatttt
    18841 agcttgctca taatctataa tacctaaaga tgcacataat tttaaattag tattttccct
    18901 caatccttca tagatattta aaatattatt aaactccttt cctgacatac ctttaccact
    18961 tgtaaccaat gagaatctat gcactccttt actctccatc tctttagctc tatttaagat
    19021 ttcattgtaa tctaataatg aatattcttc tacaccagtt ttataatgag atgattgagc
    19081 acaaaattta cagtcttcac tacatttgcc agatttagca ttcattatcg tacataaatc
    19141 tgcttttctt cccataaaat attctcttat ttcatttgca gattttaata gaatatcaaa
    19201 atcgttttta ttatttgtat caaggcttat taaattaaga gcttcttcat aacttatttc
    19261 tttttctctc aatactttat tttttaattt tattatgtat ttttccatat atcctcctat
    19321 ttgtcaactt aatattttta tgtagtttac ttattatata tagtattgca tatataacat
    19381 ttattggtca actttatttt agacacaagt ttactataca caaaaaaata ctgcttcaaa
    19441 ataatattag taaatggatt atacatatta ttattaaaac agtatttttt attagaatat
    19501 aattcttact ggtttataaa actatccttg tcttaactcc atccaagctt tccattgtaa
    19561 taacctctaa gccttcatat tctctaaata gccattttaa atccttcatg gcttgattaa
    19621 cctgactttt tgttagatta tttataaaat attcttttct agtttcctca tactctttgc
    19681 tagtcaaaaa gtttcttaga aaattaaacg caaatacact tggaatattg tttacattag
    19741 ccttcttgct gttttccttc tcatagtaaa ttttcataaa tgcatactcc tttgatactt
    19801 ttagatttct cttacaataa ttatatgcat ttaagtgcta ctattcttat aattttatta
    19861 attcatattc tttacttccc atacccattt cacatgcata gtctattatt ctagttccat
    19921 ttacatgagg atgttcatgt ttgaaaacat catgacccat ttccttacaa atcaaatcat
    19981 agcatgcttg ttcaatagct acagggtctg ttgatgctaa tattcctata tcatgggcaa
    20041 ttggtctacc tgaccaaggt acacaatcac aaagtggagt tacattcata acaaaagtta
    20101 tataccctac cttgtctttt ttatttgata ctgctccata agcgtattct gccatctttt
    20161 cgacaaacac atctgagtca ctttcccatt gtatagttac tgctctagtt ggacagacag
    20221 ttggacattc tccacatcca taacatacat cagaatctat aactgctttt ttatccacta
    20281 tacttatagc ttttgtagga caagaattaa cacactttcc acaacctaca cacttctttt
    20341 cctttactac tggagtaaca tcagaatgtt gcatttgttt tcctgctgca cttgcacatc
    20401 ccatagctaa gttttttaat gctcctccaa aacctgctgc ttcatgacct ttaaaatgac
    20461 tcattactat cattgcagaa gaattataaa tttctccacc tatttttaca ctttcaaaat
    20521 gttttttgtc tatttttaca ttctcataat ttctactata taatccatct gcaattatta
    20581 ctggtgcatt tacaactgca taagcaaatc cattttctat agcagttgta agatggtcta
    20641 cagaatttgt tctactccct gtatacagtg tatttgtatc tgttaaaaat ggctttcctt
    20701 cgcagtcttt aaccttatca accacttgtc taactgccac aggactcata tatgtagtat
    20761 ttcccttttc tccaaagtga agtttaattg cgacttggtc atttttttct attaaatctt
    20821 tgaatcctgc ttcatcaaat aatcttctta cattgtttgg tacgttttta ttttgcgaat
    20881 ttgagtataa atcacaaaaa tatacttttg acttttccat atctacaccc ctttaaaata
    20941 tttacttaaa ataattttat cacttttaaa ataatttttt agtatatttt accacaatta
    21001 aagattctta tctttattta atgaaaacaa tattatttta gtacttcact actttagaat
    21061 ttatatacta aacattgtaa ataactgaca aacattagat tataatctat ctctcttttt
    21121 ttagatagtt ccttaaggta atgacttaat tattataaag tatagtgagg atgactaaaa
    21181 taaaaaagta agtgcctcaa aatgaatttt ttagtttata agtcactttt ttgtataaaa
    21241 tcaaatatgt tttataattt taacaataaa aaagaggctt atttctctat tttgagacag
    21301 cctctttttt acttaaatat attcttctac aatactaaac acatttttcc acaatacagt
    21361 gctatttgta tttataataa aaatatcctt aaactgcttt tttattaaac aaaacaacag
    21421 ctaataatag acatactatc gaaataacaa ttgttacaat gattggaata ataaattctg
    21481 gaggtgtaac tttacctgaa actaaatcta tattttttga taatatgaaa ttaggcgtat
    21541 aaggtgcaat ctgtttagga atagaaatca aactcaaaat aacagttgct actaatacaa
    21601 gtaacacact tgcaaaagct ggtctaaata gtacacaccc aagaattaat atggaaatat
    21661 acataatact aattaaccat aagttaaatg ctgaaaatat aatatgatta agatttgcag
    21721 ttggccaaaa atacattgta tatccataag tacataaaaa gctcaaccaa aaaccaattg
    21781 tcataataat cactgcaata gaaaatttag acaatactac agatgaacgt gataaccctt
    21841 tagtcaacat aataacaagt gttcctttag aatattcgtt tgataaaata ttgcaaaaaa
    21901 caattagagt taaactcgtt ccaagaccag aaatatttcc agaaaactgt gtccaagaat
    21961 ctaaagcagt tggtgcagta gtaactttta aagttggggc aaaatgagca atcaagtctg
    22021 gcataaattt tgcagaaaga ggactcatta ttccaaatac taaaaataaa atagtcaaac
    22081 taagtaattt ataatttctt atgttctcct taaactcttt ttttgtaaat gctatgtatt
    22141 ctctcacttt actacctcca aaaataaatt ttcaagtgat aattctatta gttccatctt
    22201 tactggacaa agattcattt ctgcgagtgt agatataact gttttttgta ttgcttttat
    22261 atctttacca tgcaaaacaa tttccatatt agtttcttct gaatctttta gtaaggattt
    22321 aataccatca ctagacttaa acttttgaat ttcatcatta cttgcaaact ccagtaaaag
    22381 tctatccttt ccgtgcatac tttttatttc tgaaagtgta ccactaaggg caatgcttcc
    22441 tttgtttaat atagcaacat ggtcacagat tctttcaaca tctgatagta tatgtgttga
    22501 aaatattaca gttgttgagt ctttgatttt aagcataata tctaatattt cttttcgacc
    22561 aacagggtca agtgcacttg ttggttcatc acaaataagt aatttggggc gtgaaagcaa
    22621 agcttgagct ataccaagtc gttgcttcat tccacgagaa aacccaccta ttcgtctctt
    22681 ttcatttcta agacccacaa gtgataacaa ctcttcactc cttatctgta tttctttttt
    22741 tgaaagtccc gtaatttcac cacaaagaga aagatattca agtggtctca tataattgta
    22801 aaactctgga acatcaggca gataacctac atgacgatta gaacttgttt tcccataggt
    22861 cactttctca ccacaaacat ctatagttcc actatctggt ttaagtaacc caagtaccat
    22921 tttcattgtt gtagtcttac ctgcaccatt cttacctaca aacccaaaga ctgacccttc
    22981 tggtacagta aaatttaaat tatctattat ctttcgatta ccaaaacctt ttgataatcc
    23041 atttattgag acaatattca tcattcttca cctcttccta ttgtaaaata caaaattggt
    23101 cctattagac taataaacag tactacaata atccatattg ccttatttcc aattttataa
    23161 tttggatgtc tcaatacatg aacaagtgca gtaattataa gtattaaatc taaaataata
    23221 acaggaacca aaagtggtaa gtattccatc aaattttcca taatcttatt cctccaataa
    23281 agataatttt tctataagaa atttgtattc tttgttttca cttaatacag aaaacattgg
    23341 attattttta atagcagcaa caatacctgc ttttacgatt gtatcatcac gtgtaatacc
    23401 tgttccaatt tcagaaatcc atctgtcaag tttattaaaa aagtcatccc catgtattat
    23461 aattgggtat atatcacgtg ttgctaaatc tacatatttt cgtaatgatt taatagctcc
    23521 ttcattatca ccatgtatta aattaatttg tgcctgtgtt aaatatgaag aaagcataat
    23581 agcaggagat aatgtatcaa gctcaaatat atctgaaatt gctagaatac gtctttctat
    23641 ttccttcatt tgtaatttat ctgcattttg caaaataccc actagatttt ggactaatga
    23701 tataaggttc tgatatgcac caagttgaaa tgtttctctt gcttcatcca tttggccatt
    23761 catcatttgc ccctgtgcaa gaagtataga ttcatttatc atgggaaaat tgctgttttg
    23821 caataaatca atcacttgta tgggttgatt taacaatata taacaagttg cctccatact
    23881 ttttgcttga cggcaaatat ctatgtcatt acaagtttcc tgtatacgaa taaatatttc
    23941 taatgcttca ctaattaata gttcacgctt tttttcatct acaatatcat agtgattaac
    24001 tattaaaaga cccatccgaa aaatcaaagg aaaacatgaa taatattttt ttatgatttc
    24061 tcttatttca tccatgactt catcaaatgg tttaaccgta aagtctttgc acagtttatt
    24121 atacagttta ttaatatctt ccttcatcat ttgaggttca taacatatta actcatcaac
    24181 ggtaatgttg aaatatgtcg cgagttgcgg taaaaaggtt atgtcaggat agctttgtcc
    24241 agtttcccat ttagatacag aagctttaga aacgcctata taatttgcaa gttcatcttg
    24301 tgtaattcct ttttctttac gctttaaaat cagcgttttt gcgatgttta attcattcat
    24361 gtcaatccct ccttatgtat aattatatcc ttaaacatgt aaagctaaca agcgatttga
    24421 agttgacttt tgacgaaaaa atcaaccaca gagaaacaaa taaacaagta tataaaatat
    24481 atatttaaat ttatctttaa tctcttttgt aaaatatgta aactttgtaa ataaaatcca
    24541 tattatataa aactaatagt taatctatct aaatacagtt tttatttatc acgtttttaa
    24601 atattttgtg taaaacctct tttaatataa acaccttatt ttcatttctc atttcatatt
    24661 ctttttaaaa tactgaatat aactcttcga ttttccattt aattctttta taaagttatt
    24721 attcgtattt attcctctaa ttataacagg caactatcat gtattggtat ttgtctatta
    24781 tataaaaatc tataaaagaa aagcagtcaa tcatttagat taactgcttg tacatatatc
    24841 ttattaaact gtataaacta taatttttat tattctccat tttcatccca agtcataaat
    24901 ccccatccac tatctggata agtatcaata gacttttctc taatcatata accaacttta
    24961 taacactctt ttgttatttt attagatagt atacatcctt ctccatttat ctaattccat
    25021 ttaattaact tttcttttca accttaactt ttataaaatc atctttttta ataatttcat
    25081 acttattttc tcttcaacat catcaaatga gggtgtctca aaattaactt tttacttcat
    25141 aaggcactct tttttgtatg aagtaaaata tattttcatc atttcaacaa taagtaagag
    25201 gcttatctct attttgagac agccccattt gatggtgttg aacatttaaa taaggttgaa
    25261 ctcgttttat ctctcttttt aagatatccg taaatttgca cataaagtct cttcttcttt
    25321 tacaattcta atagttttat taaagccaaa gtatatatct ccatattctt tcgtatatga
    25381 tttattggta ctctttcatc tactccatga ccaccagttt tatacgctaa gaacttaggt
    25441 ccaaacgcca ccatatcttt aaaccaactt gcatatgtgc caccacccat agcaattgta
    25501 tatccatttt catctgttac ttcttcatag gcttctaata attttttaag tactaaatta
    25561 ctctcatcca cataatgtaa gtctttatga gcaataacct ctattttcca accattacaa
    25621 aaaacctttt tgaatctatc tattatattg tttaaaacta tatttttacc ataccttata
    25681 tctaactcac atacgatttt ttcctcattt acttttaata ttcctaaatt taaggtagtg
    25741 tttttgaata cctcatcata ttgattaatc cccaatgcat ctccataata atcactacaa
    25801 aggtattttg aaactaattc tatatcttct ctatgctgaa aatccatatt atcctcaact
    25861 atctttatta ccattttaga tatagcattt tctccctttt caggattact tgcatgtaca
    25921 gctactcctt tagtagttaa ctctgaaata attccattaa taatttttgc agtacaatga
    25981 gatggaacaa cattttcttt agttcctcca cttactatta tgtaaggttt acttttgtca
    26041 attttaattt ctttttctat ccttatatga acccttcctt tttctccatt aaccactgga
    26101 tacatagcat ctggagtaaa tcccatactt ggaatttctt cacctttatc taagtaatat
    26161 ttgatacatt tcatacctgt ctcctcattt gtaccaaaaa ttaatcttat tcttttatta
    26221 attgtaggat acatatcctc tatgtttttc aatacatgta taagcataga tacagcaccc
    26281 ttattatcta tgacacctct tccataaata atattgtcaa ttactgctcc cgaaaatggg
    26341 tctacactcc acccctctcc tggtggaact atatctaaat gcattggaat ccctattaat
    26401 tcctctccct ctccaatttc tgcatatcca atataattat caatattttt aacactaaaa
    26461 cctaaactag cacagtaatc taaagtttta tctaaagatt ttttaggtcc tataccaaaa
    26521 ggacattgtg aaataggttc accttgttgt gaatcaattt ttatcaattc ttttagaaat
    26581 tctatggttc tatttaaact attatctaca cttctgctta tatccataaa tcaacctact
    26641 ttctatcttt ttaaagcctg tccttaaaga acaggctttt aacattaaaa attatttttt
    26701 tgtaaatact aattcacaaa cttcatcatc atgagcacat ttttgagcaa aatctaattt
    26761 aacaccttgt gcgcagtcaa ctcttccata atccccataa caagctaatc tacaaatttc
    26821 ttttctttct tctttagtta atccatattc tttccaagca gcatctaatg gacagtgatg
    26881 gaattttaaa acgccattct catctgtatt ttctactaat tccatttcaa acactttttg
    26941 tcctttactg ttatataaca tttctgccat ttttcctgga gtatctgcta cgttatattt
    27001 ttgacctctc attttaccaa atccatatat tgcttcttta catatatcat ctggattagc
    27061 tcctaatttt tcagcttctt tcataagaag atagaaccat actgctcttt ctcctgttgc
    27121 tcctctaatt ccttctaaat attccttttc tgtatacatt ttttctgaca tttctttctc
    27181 ctcctaaaat taaattctat attttaatca ctgtgaatta gaatattcca atgaatgacc
    27241 ctaccaatgc taatacaact aaaattacta ataacttagt tattgtccac ttcttgtatt
    27301 tcattcccca atatacgaag aatacaacac caagtggtaa taaacctgga gcaatcatat
    27361 ttaatgtatc ttgaacaaca attgctttac caccaatatc aaatgatagc ggagttgaaa
    27421 gcttaactgt agttgcagat aatgctccca tcataaacat tcctagaatt gaagcaccat
    27481 caattatctt attgacaata ccacctgata gaattttctt aattgaatct ctacctaaag
    27541 aatatcctaa atgaaataag taataacctt cgcaaaatag taatatacta aacattattg
    27601 ggaaaaatgc acctataaca cttccttctg ctccaaatga agcacctaaa gctaagaata
    27661 ttgtttgaaa tgtaccaaaa tctaaagtat ctccaattcc agccaaaggt cccataagac
    27721 cattcttaac acctgaaata acttctcctg ggatttttcc ttcagtagct ttctcttctt
    27781 ccatagctaa aactgtaccg tgaattaatc ctccccatat agcttgagta ttaaaaaatt
    27841 gtaagtgtct ctttaacgca tctactaaat cttcttttct cttatataac ttttctaaag
    27901 ccggagtgaa acttgcacaa actgctaatg cttgcattct ttcaaaagag ttggataatt
    27961 ctgctgtcca ccaccatctt agatatgttt ttgttacatc tttctttgta agtactcttg
    28021 tcttattaac ttcagttgga ccttgtccat ttttaacttc tttatttttt atttcttgca
    28081 ttatacttca cctacccttt tgtcttcttt cataaaggta attaaaagag ctatacaaac
    28141 accaaatatt gcagctgcag taattgatat ttcaaaatat tgaaccataa aaaatcctat
    28201 aataaacatt ggtaagaatt tatttttacc tatagtaaat attgttgttg caaaacctaa
    28261 tgcaggtaat ataccgccca ttactgttaa tccattcatt aaccattgtg gtataacatc
    28321 taataatgat tgaactaaat ctgctccaaa aaagttacat acaaaaacta ttggaaacct
    28381 taaaacaaac ccaaatatta aagaataaag tgttgcacat ctccagatgc cttttgtatt
    28441 accttcttca gcatacttat ctgccttatg aaccaataca gcattaccag ttcttcttaa
    28501 gttattaact aatactccta taacacctaa aggtaccgca atagatactg caacttctgc
    28561 attaacacca gtttgaagtg ctactggtat tgcaataaga gcagctagac atttatctga
    28621 tggaatattt ccccctgctg cgaccattcc tagataaacc atttctatac ttgcaccaac
    28681 aatcatacca gttgttacat caccccaaag taatccaagg ctaaaaccta taaataaagg
    28741 agactttagt gttgagaaaa gggtataccc tgcaagacct gctgcaaacc aataccataa
    28801 tcctgttaca attgccaaca tcaaaacaga ttccatttat aattcctcct aatttatatt
    28861 ttttatttaa atttctttaa cgcattttca tatgtcatag atgattcctc tggtataact
    28921 tgtaggacta tttcaacccc attttcatta agttcattaa gttgttctac atcctcattt
    28981 cctaatgaaa cagctgtaaa caccattttc tttcctgctt catttggaat acctcctaat
    29041 tgaatctttt catatttaag tccagcttta taagccttat ttgccatatc aacattttta
    29101 aatagaataa atatattttt atctcctaaa gtgttgtttt ggaatgcttg tcccgcatct
    29161 tctgctgtta aaataactac ttctactcct gatggtgctg ccattttata tatgtcagcc
    29221 ataaattcat cttgacctaa gaagtcatca actattatta ttttttgagc ttgagcgatt
    29281 tttacccatt ttgttataac ttgcccatga attaatctgt ggtctactct tactaatgtt
    29341 atttttgcca ttatattcac ctcataattt atattttttt aaattcttta attaaatcca
    29401 cacaaaggtt attatttttt ttgacgattc tttctggtaa tgtatgtaat ttatcttctt
    29461 tgcttaattc ttcatctacg attaaaattg tctgtaagct aagtccattt attgcatcta
    29521 ttcctcttct tatagcaaca gctattgcga cacttgatgt agatcctcca tataaatctg
    29581 atattataat tttcacatct tctttatcta ctacttcttc aacctctttc ataaatacag
    29641 aaacatcttt ttcagaactt agtgataaaa cttcatattg atttgacaat ccaaagtttt
    29701 tatttgtttc ttctactaag acttttcccc aagttccatg gcacagtatg attaccttat
    29761 atttattcat tgctaaataa actctccttt atagcgatta atattttggt ttaattctac
    29821 ttcttcttca tcaggtacca tttgaattga tacattaata ttctttttaa taaattcatc
    29881 tattaaaaga aactcttttt tattaatgta tacattttga gatattttct tttttcctat
    29941 tcctgtaggt attcttccaa caataagttt tttgatatta atcccttctt ctatcattct
    30001 atttgcagta tctaaatttt taattaatac aaaaacgtta tcatcagctt gattattata
    30061 aaaatatctc cttgattcac ttacagttaa tattgataaa tcaatattct ttggtgctgc
    30121 catttttatc aaacctttag caataacatc attggttgtt tcatcatcta ctactactat
    30181 cttttttaca cctagatgct taacccattt atatataact tgaccatgta ttaatctatc
    30241 atcacatctg caatatttta ctaaagacat ttttaatcaa actccttttt ctattacatt
    30301 gagctaagaa ctttattaat attgtttata ccagtttgtc ctgcttcaat acatgcttct
    30361 gctaactctt ctaaactttt tccctctcta ttaattaaag cttcaagtag cattggaaga
    30421 tttactccag taagtgcatg aaacttgcca ccttttttaa ggtttaaact tgcaacatta
    30481 cttggagaac ctcctaatag gtcagctaat actaaaactc cgtcaccttc atctaattca
    30541 tttaactttt ctacaaaatt tttatttaag tcttcaatat tatcattcct atttagttta
    30601 attgctgctg ttctttctgc tggtcctgca ataagttcac agctttttat aatttcttca
    30661 ctaaaactcc catgagtcat aactattatt cctatcacca atttcacctc acttttcttg
    30721 tcacttttta tataagcaat tgccgtgcca acttatgtgt atcaataaca aatggctatt
    30781 ttacaggatt taatcaaaac tttttactca atttttttta aaaacttatt atttcgatat
    30841 gtatcaaaag attttttcaa cctgtatcaa atctgtatca aaaaaagtaa aaaaaagata
    30901 gccttttggc tatttttaaa ttttgtatca acttttgaat ttatctgtat catattgtga
    30961 ttcaaatata tctaatatat ttgcatattc catatctgaa ataattatat cgaatgtctc
    31021 ttctactagc ttaaaacttt cttttataac taaatataat tctttatttc tactaattct
    31081 ttcttcatat gatttataaa ctaaagactc ttttattatt actctttcaa tcatacatga
    31141 acaatgaaat ataaacttta ctaaaagttc atcttgaatt actaaagaat agtgttcact
    31201 aattctatta attacttctt ttaatataaa ataagccttt tccccattta aaaaagtcaa
    31261 agttttacta atattatcaa ttagtaatct atcaaaatat ctaccaccat tatctttttc
    31321 agcatatgta acttccatat ctccataatg tttctttata gattctataa tattaaaata
    31381 taatttctct aatgtcattt ctggagttag agcctttcta gttgcttcta ttacaatagg
    31441 tgtacttacc atatctattg cttttacttc ttttcctgta gcatcacgaa taactttagc
    31501 aaatgttaaa atagacccca tatcagttaa aattaaaatt ccctttcctt tatcaatttt
    31561 attggctatt tctacagctt gtactaaaat atcctgaact ctatcttcta atcccatatt
    31621 aattgccact gcatggttac aatccagtaa agtattggct acattcacca tgctagatgc
    31681 tgtagattca ccatgcatta tgactaatat tgctatactc tcctcattta atcccacata
    31741 cgataaataa agaaatgttg ctaaaaaaat tgcttcatct tctggaaact ctactccata
    31801 cattaatgac atgttagata atatttcttt tgctatgtta tattcatatg ctctttcctt
    31861 cataatttca tctttattag gatgctttac tatatttcca atctttattc tttcaattaa
    31921 attctgaata tgtaaagcta tagcttttat taatttatct aatccttctc ttttgctcca
    31981 tttatcatgc ttttgtaaaa tatattttac agtagttgca attgaatcat taacaatgtt
    32041 gttataagct gtttgattac tactattata tataaaagta ttcattaaat tataggaata
    32101 cttctgtatg tctccatcta taacacttct aatttgtgac tctttaatac cttcttgttg
    32161 aagtttattc caagtttctt ttatcattcc ataaaaatct aaatcatatt ttttattttc
    32221 tattaataaa ttttcacttt caaaatcctt ttcttctggt aaaaaaataa tatcatcttt
    32281 tccaataaaa ctgaaatttt gtacaaactc ctcttttcta ttatttccat ataatgattc
    32341 tctaatatta tttggtagaa gagagagcct tacatataca cattcccttt tataggtcat
    32401 ataatctaaa aaagctcttg cacaaattaa ttgtatatcg ctttttaatt ggcctatatt
    32461 tcccttacac ttatataaaa taaatgcctt aataacttct tttgaaacct ttaacttaac
    32521 accaatccta acactctctt ctttaaaaaa ataacatata agcttcattc tctcttgaaa
    32581 gcctctttcc tctaaagacg gaatctttat agttacaggt attcttctta aaaacgtttc
    32641 caacattgct gtttctgggt cttctgtagt ggctgcaatt atcataactc tacactcgtg
    32701 taccttatta gcctctccta accttctata tatcccttta tccataagca gaaatagcat
    32761 ttcttgtccc tctgcagata atctatgaac ttcatctaaa aacaatactc cattattagc
    32821 ttcatgtaca ataccatact tatctttatc agctccagta aatgctcctt ttacatatcc
    32881 aaaaagctgc gctaataata attgctgatt atcagaataa tcagcacagt taaatatgat
    32941 aaatggtgca ttatcactat cttcttttat agttaaacta tacttataca tatattctgc
    33001 aaatatagat ttaccaactc ctgtaggtcc tattattaat gtacttaacc ccttaggtgg
    33061 atatattact gctgctttag cctgttctat ttgggacctt aaacttccat cacatcctac
    33121 taaattaaaa atattgttct ctttttttat actctctaaa atatactcat ctttgataga
    33181 atcattttca ctatattcgt ttatagagtt aatattatca aatatccctt tatttagttt
    33241 ctttcctaaa atactctcaa tactttcttt atataagtac tgaacaggct taccctttat
    33301 ctttataata atactttctt ttattaattg atttaattcc ttactagcat tacttctatt
    33361 tatacctact tcagtagcta tatattctgc atcaaatcca aatctaatgc cattattaaa
    33421 gttcaagtgt tcttctgtta accttttcaa gcaaattaaa actttttctt tccttgatag
    33481 cttcttttgt gtcatagtta acctccccta taagcagtaa tactgttaaa catttattat
    33541 taagcttaat tctacaatat tttaatattt ttgtctaatt atgtaactat tgattttctt
    33601 tcctattcgt tttataatat aaattacgtt accctcatct tttatagagg aggaatttat
    33661 atgaattttt tatcagattt acacacccac tctatagtca gtggtcatgg ctatagcact
    33721 ttactagaaa atattaatta ttgtaaagaa aatggaatta agatactagg tacatctgaa
    33781 catggtccta agatgcctgg ttctccccac agatggtact ttcacaacat tcaaaatatc
    33841 ccaagaatca taaataacat tataatttta agaggctgtg aagcaaatat actagatatt
    33901 aaaggaaaca tagacctaga gccttttgta attcctcggt tagattatct tatcttgtca
    33961 tttcacgaag ctgtgttttc tccaaataca ttagagaata atactaaagc tttaataaat
    34021 gcaataaata agcatgataa tattgaaata ttaggacacc ttggaaaccc aaactaccca
    34081 atcgactatg aattaatcat taaattagct atagaaaaga atatcttaat agaaataaat
    34141 aattgttcta ttaaaggcgt gtcaagaaat ggtagctcgg ataactgtaa gtatattgct
    34201 acactttgca aaaaatatgg tgctaaaatc atactaactt cagatgctca catttgtttt
    34261 gacataggta actatgagta ttctgaaaat atcttaaagg aaattaattt tccagataaa
    34321 ttaataatga attatcctaa aaaacttatt aatcattttc accaaaaaga taaattacta
    34381 gatgttgatt atacaaatat ctaagtaata atacatgctt actttaactc ccataaaaat
    34441 tttaatacta tttatattat atgaaataaa gaaattataa taaagaagct atttaataaa
    34501 gcttaattac ttttatgaac ttgatggatt gatatggtct atgatagcaa tagaaattat
    34561 aacattttta ataagcttag ttttatatac cttatagtat aaatctaaaa aagcatcatc
    34621 taaaaaggag ctgtcgcatg agcaaattaa atttgttcta tgatagctct ttctttactt
    34681 attttaatta ggtatatttt taattatttt atataaagct tatgttctaa gtaaaattat
    34741 gcataacaaa caaaggtata aaaataccat tttttcagat aatatttaat tataaataat
    34801 aaatttagaa tacttctttt aaatgatgag agtctagaaa tttttatgtg tattctttaa
    34861 ataaaaattt ccagactcta g
//
LOCUS       DAEQAF010000037        33637 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.038, whole genome shotgun sequence.
ACCESSION   DAEQAF010000037 DAEQAF010000000
VERSION     DAEQAF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33637
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.038"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            111..1397
                     /locus_tag="KRN00_001843"
     CDS             111..1397
                     /locus_tag="KRN00_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBH1827709.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            1509..1982
                     /locus_tag="KRN00_001844"
     CDS             1509..1982
                     /locus_tag="KRN00_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:1641..1643,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBH1827710.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            2014..3324
                     /gene="grdB"
                     /locus_tag="KRN00_001845"
     CDS             2014..3324
                     /gene="grdB"
                     /locus_tag="KRN00_001845"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:3061..3063,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBH1827711.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            3580..5112
                     /locus_tag="KRN00_001846"
     CDS             3580..5112
                     /locus_tag="KRN00_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBH1827712.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFIAERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            5123..6268
                     /locus_tag="KRN00_001847"
     CDS             5123..6268
                     /locus_tag="KRN00_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBH1827713.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDIVLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            6578..7657
                     /locus_tag="KRN00_001848"
     CDS             6578..7657
                     /locus_tag="KRN00_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1827714.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            7770..8369
                     /locus_tag="KRN00_001849"
     CDS             7770..8369
                     /locus_tag="KRN00_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827715.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SNQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(8556..9428)
                     /locus_tag="KRN00_001850"
     CDS             complement(8556..9428)
                     /locus_tag="KRN00_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1827716.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIEYMASIHIN"
     gene            9845..11248
                     /locus_tag="KRN00_001851"
     CDS             9845..11248
                     /locus_tag="KRN00_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827717.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            11275..12819
                     /locus_tag="KRN00_001852"
     CDS             11275..12819
                     /locus_tag="KRN00_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH1827718.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLSKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            12850..14241
                     /locus_tag="KRN00_001853"
     CDS             12850..14241
                     /locus_tag="KRN00_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBH1827719.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            14434..15930
                     /gene="abfD"
                     /locus_tag="KRN00_001854"
     CDS             14434..15930
                     /gene="abfD"
                     /locus_tag="KRN00_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBH1827720.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            16065..16340
                     /locus_tag="KRN00_001855"
     CDS             16065..16340
                     /locus_tag="KRN00_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827721.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENIEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            16364..17671
                     /locus_tag="KRN00_001856"
     CDS             16364..17671
                     /locus_tag="KRN00_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBH1827722.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVRESLAVEFEKRFKEKY"
     gene            17691..18809
                     /locus_tag="KRN00_001857"
     CDS             17691..18809
                     /locus_tag="KRN00_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH1827723.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            19096..20016
                     /locus_tag="KRN00_001858"
     CDS             19096..20016
                     /locus_tag="KRN00_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBH1827724.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILPIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            20131..21288
                     /locus_tag="KRN00_001859"
     CDS             20131..21288
                     /locus_tag="KRN00_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1827725.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(21373..22872)
                     /locus_tag="KRN00_001860"
     CDS             complement(21373..22872)
                     /locus_tag="KRN00_001860"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBH1827726.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            23468..24892
                     /locus_tag="KRN00_001861"
     CDS             23468..24892
                     /locus_tag="KRN00_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBH1827727.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDALFKRLESK"
     gene            24927..27056
                     /locus_tag="KRN00_001862"
     CDS             24927..27056
                     /locus_tag="KRN00_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH1827728.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKNFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSRIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            27086..27508
                     /locus_tag="KRN00_001863"
     CDS             27086..27508
                     /locus_tag="KRN00_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1827729.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            27527..28678
                     /locus_tag="KRN00_001864"
     CDS             27527..28678
                     /locus_tag="KRN00_001864"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1827730.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEDILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      28784..28885
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            29068..29640
                     /locus_tag="KRN00_001865"
     CDS             29068..29640
                     /locus_tag="KRN00_001865"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBH1827731.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            29704..30354
                     /gene="fsa"
                     /locus_tag="KRN00_001866"
     CDS             29704..30354
                     /gene="fsa"
                     /locus_tag="KRN00_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH1827732.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            30506..33430
                     /locus_tag="KRN00_001867"
     CDS             30506..33430
                     /locus_tag="KRN00_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827733.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGVGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIESEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
BASE COUNT        13216 a         3754 c         6334 g        10333 t
ORIGIN      
        1 ataaaaacac aataatatat ctttaaaaaa ataagataaa ttgtaaaatg atataatttt
       61 gagaaaaact caaatgcata tacacaaatt aaataacagg aggtgcaagt atgcgtcttg
      121 aattagggaa aatctttata aaagatattc aatttggtga tgtaacagaa gtaaaagatg
      181 gagtattatt catcaataag caagagatgc tacaagaaat tggtggagat gagcatatta
      241 aatctataga tatagaatta gctcgtccag gtgaaagcgt aagaataaca cctgtaaaag
      301 atgttattga gccaagagta aaagttgaag gtaatggggg aatcttccct ggtatcatgt
      361 ctaaagttga cactgtagga gaaggaaaaa ctcatgcttt aaaaggtgta gctgttgtaa
      421 ctactggaaa aatagtaggt ttccaagaag gtataataga catgactgga gaaggagcta
      481 agtacactcc attttctaaa ttaaataatg tagtagtaat agctgaacct attgatggtt
      541 taaaacaata cgctcatgaa aaagctgtta gaatgatagg attcaaagca gcaatgtact
      601 taggagaagt agcaagaaat cttactccag atgaagtttc agtatatgaa actaaacctc
      661 ttcttgaatc aataaaagaa tatccagagc ttccaaaagt aggatatgtt tacatgcttc
      721 agactcaagg tttattacat gatacttatg tatatggagt agatgcaaaa caaatagtac
      781 caactttatt atatccaaca gaattaatgg acggagcaat tgtaagtggt aactgtgttt
      841 ctgcatgtga caaaaaccca agttatgttc atataaacaa tggggttgtt gaagacttat
      901 atgcaagaca tggtaaagat ataaactttg taggtgtaat tataactaat gaaaatgttt
      961 atctagcaga taaagaaaga tcttcaaact ggacttctaa attatgtaaa tatttaggat
     1021 tagatgcagt tatagtttca caagaaggtt ttggaaatcc tgatactgac cttataatga
     1081 actgtaagaa gatagaaatg caaggtgtta aaacagttat agttacagat gaatatgctg
     1141 gacgtgatgg aggttctcaa tcacttgcag atgcagatgt aagagctgat gctgttgtaa
     1201 caggtggaaa tgccaaccaa gttgtagttc ttcctaagtt agataaagtt attggacatt
     1261 tagaagtagt agatgtaata gctggtggtt ctgatggaag tttaagagct gatggaacta
     1321 ttgaagttga aatccaagct ataacaggtg caactaatga aacaggattt ggtcatttaa
     1381 ctgctaaagg atattaagaa gtattttatt aaacgattga gtaatgttaa taaaacatat
     1441 tatagataat tataataagt gttatagata tataaaaata tattagaaat ataataagga
     1501 ggattattat gagtttactt agtaataaaa aggttcttat aataggtgac cgtgatggta
     1561 taccaggacc tgcgatagaa gaatgtgtaa aaacagtaga aggagcagag gttgttttct
     1621 catctacaga atgctttgtc tgaacagctg ctggggctat ggacttagaa aatcaaaaca
     1681 gagttaaaga tgctgctgat aaattcggag ctgaaaatgt tgtgatttta ctaggtgctg
     1741 ctgaagccga agctgcaggt cttgcagccg aaacagtaac tgctggagat ccaactttcg
     1801 ctggaccact tgctggagtt gccttaggat taagtgttta ccacgttgtt gaggaaccaa
     1861 taaaatcatt atttgatgaa agtgtatatg aagaccaaat aagtatgatg gaaatggttt
     1921 tagaagttga agaaatagaa gaagaaatgt ctggtataag agaagaattt tgtaaatttt
     1981 aatgcctaaa agcaaaaggg gtgaaactaa gagatgggaa aactaaaagc agtacattat
     2041 attaatcagt tctttgctgg tataggtgga gaagaaaaag ctgatactaa gccacatgtg
     2101 gcagaaactt tacctccaat aagtttacaa cttgataaat tattaggtga agatattgaa
     2161 atagttggaa cagtagtttg tggagatagc tatttcaatg agaatataga tagtgcaagt
     2221 gaagaagttt tatcaatggt aaaaggtttt gaaccacaac ttttcatagc tggtcctgca
     2281 tttaatgctg gtagatatgg ggttgctgct ggaacaataa ctaaagttgt aaaagatgct
     2341 ttgaatatac cagctttaac aggtatgtat gttgaaaatc caggagcaga tatgttcaaa
     2401 aaggatgttt atgtagtaga aacttctgat tctgcagcag gtatgagaaa ggcacttcct
     2461 aagatagcta aacttgcagt aaaacttgct aatggagaag aaattggaac tcctaaagat
     2521 gaaggataca tagctagagg aataagagtt aactacttcc atgaagacag aggttctaag
     2581 agagctgttg acatgttagt taagaaaata aaaggtgaac catttgaaac tgaataccca
     2641 atgccaaact ttgatagagt tgacccaagt aaagctgtaa aagatttatc aaaatgtaaa
     2701 atagctttag ttacttctgg tggtatagtt ccaaaaggaa atccagatag aatagagtct
     2761 tcttcagctt ctaaatatgg aacttattct atagcaggag ttatggattt aacagaagag
     2821 acttatgaaa ctgcacatgg tggatatgac ccagtgtatg caaatttaga tgcagataga
     2881 gtattacctg ttgatgttct tagagattta gaaaaagaag gtgtaattgg aaaattacat
     2941 gagactttct atacaactgt aggtaatggt acatctgttg caaactctaa aaaatatgct
     3001 tctgaaattg gagcagcatt agtggctgat ggtgtagatg cagtaatatt aacttctaca
     3061 tgaggtactt gtactcgttg cggtgcaacg atggtaaaag aaatagaaaa aactggactt
     3121 ccagtagttc atatgtgtac agtagtacct atttcattaa cagtaggggc taatagaata
     3181 gttccaacta tagcaatacc tcatccactt ggaaatccag cgcttgaccc tacagaagaa
     3241 aaagccctaa gaagaggcct tgtagaaaaa gcattaaatg ctttaactac agaagtagat
     3301 ggtcaaacag tatttgaaaa ataaaaataa cacacacata tattatatag ataaaaatat
     3361 aaacacacac taaaaataaa aaataactat acacaaaaaa ataatataga tttcatgaat
     3421 ggataaattg gagttattca ttcatgaaat cttaaaaaat gccaaaatac ataaacaata
     3481 atagaatcaa atatacaata aaatacaatg attagagctt ttaataagtt taataagatt
     3541 aaaaaataag tgttcataaa atttatggag gtgcacaaaa tgacttatcc agttttaaaa
     3601 ggggcaggct atgtacttat tcatactcca gatatgatag tgcaaaatgg aagtacttgt
     3661 acagttgaaa gagcaacaaa tccagattca gaatttttaa aagaagtaag taatcatata
     3721 agaagttatg aagatgtagt taactacatg ccaaatcaag tttatatagg aaatagaaga
     3781 ccagaagaat taagagattt accaatgcca tggtgtgaac aaaagattga gggaactaga
     3841 aatggtaagt ttggagaaat aatgcctcaa gatgagttca tagctttaat gcaaataagt
     3901 gatgcatttg atttagtaaa attatcacaa gaatttattg atgaagtaaa gccaaaaatc
     3961 gaaaataact accctgaaat tgcaccattt gtaggtaaat taaagggtga tgatatagaa
     4021 gaaggtaaag aattagtagc aacacacata gctgaaggat tataccatga tggaaaattt
     4081 gttggttatg taaaaagagc acatgatgta gatgttaact taaatgccca tacaatgttt
     4141 gaaaatctag tagtaaaagc atctggagtt ttatctgcta ttcaaatgct aagacatagc
     4201 aaaatagacc ctgctgaaat agattatgtt attgagtgtt cagaagaagc ttgtggagat
     4261 ataaaccaaa gaggtggagg aaactttgct aaatcaatag ctgagatagc aggacttcaa
     4321 aatgcaactg gttctgacac aagaggattt tgtgcagcac caactcatgc attaattcaa
     4381 gcagcagctt tagtaaaagc tggtatacat aaaaatgtaa tggtagtagc aggtggagca
     4441 agtgctaaac ttggaatgaa tgctaaagac catgttaaaa aaggtcttcc tgtacttgaa
     4501 gatgttgttg gaggatttgc agtacttgta tctgaaaatg atggtgtaaa tccagttata
     4561 agaactgatt taacaggtaa gcatactgtt ggaactggtt cttcaccaca agcagttatg
     4621 acagcactta taacttcagg tcttgataga gctaatttaa aaataacaga tgttgatgtg
     4681 tattcagttg aaatgcaaaa cccagatata actaagccag caggagcagg agatgttcca
     4741 gaagcaaact acaaaatgat aggggcactt gctgttaaac gtggagactt agaaaagaaa
     4801 gaattgaaag attttgtttc taacaaagga ttaccaggat gggcaccaac tcaaggacat
     4861 ataccatcag gagctcctta tataggattt ttaatagatg atttaactac aggaaataga
     4921 aatagagcta tgatagttgg aaaaggtagt ttattcttag gaagaatgac taacttattt
     4981 gatggagtat cttttatagc tgaaagaaat acaggtgtta ctgaagagac ttcaggaata
     5041 tctaaggatg aaattaagaa gataatagct gaatctatga aaaaactagc attagatatg
     5101 ttagaagaat aggggtgagg atatgtcaaa aaaagtaatc gcagatgtat tcttagaagt
     5161 agctaatgca atagaaagcg gcgaatttgg caaaaaagta aaaattggtg ttactacact
     5221 tggaagtgaa catggtgtag aaaacatggt taatggtgca caattagcaa aatctaattt
     5281 atttgatatt gtgcttattg gaccaaaagt ggaaactgac cttgaagtag ttgaagttaa
     5341 tgatgaaaaa gaaatgcatg caaaaatgga agaattatta gattcaggat atattgatgc
     5401 ttgtgttact atgcattata attttccaat aggtgtatct acagtaggta gagtaataac
     5461 tccagcaaaa ggaaaagaaa tgatacttgc aacaacaaca ggaacaagtg ctactaatag
     5521 aatagaggca atggtaagaa atgccattta tggtattgct acagctaaat caatgggtaa
     5581 caaatgccca aaagttggaa tacttaatgt tgatggagca agacaagttg agaagtgctt
     5641 aaaagaatta aaagataatg gatatgacat ggagtttgcg gattcaatta gagcagatgg
     5701 tggatgtgta atgagaggta atgatttact tgtaggtgca cctgatgtta tggttactga
     5761 tacattatct ggaaatatat ttatgaaagt attttcttca tatactacag gtggagatta
     5821 tgaagctcaa ggctttggat acggacctgg agttggagag gactatgata gaaaggtact
     5881 tatagtatca agagcatcag gttctccggt agtagcaaat gctttaaaat acgcttatga
     5941 tgttgtaaag ggagatataa gtaatgttgc aagaaatgaa tttgcaaagg ttaaaaaagc
     6001 aaaatttgat gacattatat cctctcttac taaaaaagaa gttaaagctg aaaaagtaga
     6061 agttaaaatg ccagataaag aaattgttac tcgtcaaata gctggtgttg atataatgga
     6121 tttagaagat gcagtatctg agttatggaa aaacggaatc tatgctgaaa gtggtatggg
     6181 ttgtacaggt ccaatagttt tagtaaatga agctaaagga gacttagcag ttgaaacttt
     6241 agttaaagct ggatatactg caaaataagt acatttttta tatgtaaata agaacatata
     6301 gttataattt tattgattat aattatatgt tctttttatt ttatatcttg tcaatattta
     6361 tatattaaca caatccattt atttgattct ctagctaatt tattatattt attcagttaa
     6421 aattaagctt tctaactaaa taaaaactaa tgaagtatta aaatgaaatt gataaaatat
     6481 gaaaaaattt taggaataaa gtatctgtta gataaaaata agattaatta gtgatataat
     6541 ataattaaga taaaatttat tatttggagg caaaatcatg agcagagtaa aaaatgtagt
     6601 agaattgttg gaaactaaag gtgttgatgc actatatcta acaaagaaaa ctaatgtaaa
     6661 ctatataagt ggttttcctg atgaagaagc atatgcagtg atttgcaaag atggaaactt
     6721 tttagttact gatagtagat atatggagct tgcagaaaag gtttgcaaag attttgaaat
     6781 tataaattgg cataattttg atagaagtgt ggcaaaggca gttaaaagtg tatgtgataa
     6841 agtgggtata aagaaacttg ggtttgaaag aactaatata gtgtttgata aatatgaaga
     6901 acttaaaaat ctgattgaga aggataatgg agaattaata cctacagaaa atattgtaga
     6961 gactttgaga tatgtaaaag acaaagatga aatcaaaaat acaagaaaag cttgtgaaat
     7021 agcggataag gcattagaag aattgattcc acatataaaa gctggagtta gcgaaattga
     7081 actggctaca aagttagagt actttatgaa aatgaacgga gcacaaaata tagggtttga
     7141 aactatactg atatcaggag caaagacttc attgcttcat ggtaagccta gtgataagat
     7201 tatagaaaaa ggtgattttg tacttataga ctatggcgct atgtataatg gctatatatc
     7261 tgatacaact agaactttta tagttggagg agcttctgaa aagcaattag aaatatataa
     7321 tttagttaag gaagctcaaa atgtaggggt tgagaacatg aaagctggtg tacatgcgac
     7381 aattccagat gctgagataa gaaaagttgt caaaaaatat gaagactatt actatcaagg
     7441 tataggacat ggagtcggta gagatgttca tgaagaacct ttcattggta attatggtga
     7501 taaaatcata gaagagggat gtataataac aatggaacca ggtatttatt tccctggatg
     7561 gggtggagtt agaatagaag atactgtttt gattactaaa aatggtccag aaagacttac
     7621 taaattccct aaagatttga tgattttaga caaataattt aatttatata tattttttta
     7681 cataaaatat aacataatct cactattaag ctctatttac atattatagt aaagagggct
     7741 taattttatt gtgagaggtg atagtatata tgtataaaaa acataaattt ataaaaaata
     7801 taaaaaaagc ctggtataaa atcaaattaa ttgatagatg ccttataatt gtaatggcaa
     7861 tattaatgtt tcaatctata tataatttat ttgttaatga agtaaattca caagatacta
     7921 caactattga tgtagtagta agaaccactt cagcagctat atttgggtat tttttaagtg
     7981 ctaattttat aaagagacct ttaaggaagt atacaaatac tgatgtatct tcaaatcttt
     8041 ttatagataa taatttatcc ccaaaaggtc aagagtctaa tcaaaataat ataatgaatg
     8101 tcaaaaatac cattggattt acttcagaag ctgataatta tgaaaagaaa atacctatta
     8161 ataataatga aggttttgaa gaaggagaaa ctagtgaatt gcaaattatt atagctactg
     8221 taatttgtat agtagcatta acagtacttt ttgttgtaag aaattttaca actacaacat
     8281 cagcttcttt aggtactatt tcacagatga gagattttgt ctcaggatgc gtgggttttt
     8341 tgctaggttg tccaagtaaa cctgattaaa aaagtattat caataaaagg tattttaaaa
     8401 agtatcagta taataatatt tagatttaaa tgtatacaat tataattcta taacattcta
     8461 tattgtattt ttatactgat actctaaact atactattta ttaaaatatt ttaacattgt
     8521 atttaaacaa aatattatat ctgtataata taaatttagt ttatatgaat agatgccata
     8581 tactcaataa aaagtttcat actatgagat atgtattgat ttcttctcca aagaacccca
     8641 atatttgcag taattgcacg ttctaatggt attgaacaga gattttctgt attttgaaat
     8701 atttctttat acaatattgt tgaagccaag tcattttcta gtaaataacg tatggtagaa
     8761 agttgatttg agtgtaaaat tatatttggc ttagcttttt caagtctttt tgtaataatc
     8821 ttatagtgat aagaaccttc agataagatt acaaaaggta cattttttaa catataattc
     8881 gatataatag gatgttttgc caattcattt ttgggatttg taactaagta taattctgtt
     8941 ttatagattg tctttgaatc tatatcatca taaatatcac tgtcaattat accaatacaa
     9001 aaatcaagtg tagattcttc aatcatttta gctccaacaa atgttggaac ttcaaaaatt
     9061 ttaagctcta tatctggata aattacatta aacctaggaa gtatttttga aagcaaaaac
     9121 gtacctaaaa ctgtaggaat acctattttg agagaagctt ttctcttttt tcctaaatca
     9181 agtgcgtcac attgaaaatc ctcaaattgt tttataaaat gttttgactt gtctaaaaaa
     9241 atttttcctt caggcgttaa ctctatttta ttacctattc tgtaaaaaag ttcaaagcca
     9301 agttcttttt ctaattcttt aattgctaat gttatggatg gttgagaaat atgaatactt
     9361 tccgcagcct tagtcatgtt tttatattta cagacagttt gaaaatagta taaatagttt
     9421 atattcattt ggtattagtt cctttcattt acatattagt gacaagtata taattaacaa
     9481 tagcataagt tttgtatatt gttgtaaaaa aatagaatag ttttaaacta tcatagcata
     9541 agtttttgat attttcaatc tattaagaat agtgctatta ttaaattaac aaaagagaat
     9601 agctggtatg gtttagagta aatcaatcta tattacagtt atatcaacga atatcaaaaa
     9661 attatctatt aaaaaataaa aattattttt acaattaaat tgttaattaa atcataaaga
     9721 aaaaagtgat attaacaaga taaaattttt ttaatcagaa atgttaattt aataacaaaa
     9781 tagagtattg gggagaaagg agaaatatat tttttaataa tatttgttaa tttaataacg
     9841 aaaaatgaaa gggagtgatt tagtgaagtt tgaattgatg gattttttaa tgaatccttt
     9901 tgtccttatg tttgctgcag taattacagg aattttattt ggaaaaatta aatttgggaa
     9961 gtttaatttt ggggtatcag gagcattatt tacaggatta tttattggat ggcttgcata
    10021 tagcttgggg aatctaataa tagcaaaagg ggaaacagca gcaggatata aggcagcaac
    10081 tgtaatgatg gggaatggaa ttatttcttc tgacttcttt gatttctttt taataatatt
    10141 tgttgcagca gttggtctat tggcagcaaa agatatgaaa gctgtattaa agaagtatgg
    10201 agcaagattt gtaattttag gagttcttat aacttttata ggtggctcta tgacttatgc
    10261 aatgacttta ctatcaagtg ataaaggaag tagtgcttat gaagtttctg gcgtttacac
    10321 aggagcatta acaagttcgc ctggattagc tgctgcttta gaaacagctg gtaaacatgc
    10381 agaagatgta tcaaaagaat ttgaaaaagc ttcaataaaa gataaaaaag aaattttaaa
    10441 agtagtcgac ccagaaggca aattggatgt gaatacaact acatcactga ctcaagagca
    10501 aatagataag tatattgcat atgctgaagc tggtgttggt ataggtcatg cagtcgcata
    10561 tccttttgga gttttaatag taatcttagg tgtaaatttc cttccaaaat tatttaggat
    10621 ggacctaaaa gaagaaagaa gaaaatatga gaaggaaatg aaggaagcaa gagatagtgt
    10681 ttctggtaaa acgataccag aagttccatt taatataata acatttttct tgacatgttt
    10741 agctggatac ttagttggag gaatacatgt atttatggga ccactagggt acttcacact
    10801 aggtgcaaca ggaggttcac taattgtatc tctagttctt ggatatatag gtaagatagg
    10861 ggtagtaaat ttcagaatgg aagaaaaggt tttaaatatt ttaaaacaaa tagggctagt
    10921 atttttctta gcaatagttg gattaagata tggtggaaaa gtagttgatt caattatgac
    10981 atctggtatg catctagcct tagtagcaat agcagtaggt gttacagcta tgatgatagg
    11041 attcttggtt ggcaaatacg tatttaaatt aaattggatt ttattatctg gagctgtctg
    11101 tggtggtatg acatcaacac caggtcttgg agctgctgtt gatgctcttg atagtgatga
    11161 cccagcagca ggttatggtg ctacgtatcc atttgcatta ttaactaaag ttatattggt
    11221 tatagtttta cacaaacttc caatgtaaat aagattttat atggggggat atttatgaat
    11281 aatgaaggag catttgaaga attaagtgga agattaagaa ataaagaatt gtgtgattta
    11341 ataatgaatg cagatgaagc tgctaaaatt atagaggatg gcatggttat tggagttagt
    11401 ggatttacac cttcaggcta tccaaaagca gtaccattag cagtttcaga aagagctaaa
    11461 agtggagaaa agataaaatt aaccgtatat tcaggagcat ctttaggtcc agaagttgat
    11521 ggagcatggt cagaagcagg tataattgaa agaagacttc cttatcaaac taattcaata
    11581 cttagaaata atattaataa aggtgttgtt gattatatag atatgcacct aagtcattct
    11641 actcaatttt taaattatgg aactatacct aaagtagatg tagctatagt agaagcactt
    11701 gcaataactg aagaagggaa tattatacca actagtggga taggtaattc tccatctttt
    11761 ataaaaagtg cagataaagt aatagtagag ataaatcttt caaaaccaat ggaaatggaa
    11821 ggtatggcag atatatatat tacggaaaat ccaccaaata gaaaaccaat agaaataaat
    11881 catcctaagg atagaattgg aacaacatat ataccttgtg gtttagataa aattgcagga
    11941 gtagtaatta ccaatatgca agataagacc cgtccattgg gggttgtaga tgaagcttcg
    12001 aaaaaaatat caaataatat tattgctttt ttaagagaag aagtaaaggc aggcagatta
    12061 tcaaagaatt tacttcctct tcaatctggt gtaggaagtg tagcaaatgc agtattatat
    12121 ggattatgtg aatctgaatt tgaaaattta acttgttata cagaggttgt acaggactct
    12181 atgttggatt taataagaat gggtaaagtt acaatggcat ctactacatc tgtaagtcca
    12241 tctccagaag gattaataaa atttgaaaaa gatattgatt tttttaagga taagattata
    12301 ttaagacctc aagaaattag taacaatcca gaaatagcca gaagaattgg tgtaattgca
    12361 atgaacactg caattgaagt tgatatttat ggaaatgtaa attctactca cataatgggg
    12421 tcaaagatga tgaatggaat tggtggttct ggtgattttg ctagaaatgg agcaataact
    12481 atatttagta ctgagtcaat tgcaaaaaat ggtgatatat catcaatagt acctatggta
    12541 tctcacgtag accacactga acatgatgta atggtaattg taacagaaca aggatatgct
    12601 gatttaagag gtcttgcacc tagagaaaga gctataaaaa taatagaaaa ttgtgcccat
    12661 ccagattata aagaacaact tagggattat ttaaatagag cttgtaaaag tggagcaaaa
    12721 caaacacctc acatattgga cgaagcttta tcatggcata gtaaatttat gagtacaggt
    12781 acaatgaaaa aggctgaaac ttttaaaagt gcattataaa atatttaata aattggaggt
    12841 agattttaaa tggaaaaagc agtggaaaac tttgaagatt taagtaagga atacattaat
    12901 ggttatattg agagagcaag aaaagctcaa agagagtttg aatgttatac tcaagaacaa
    12961 gtagataaaa tagtaaaaat agttggaaaa gtagtgtatt ataatgctga atatttagct
    13021 aaacttgctg tagaagagac tggaatggga gtatatgaag ataaggtagc taaaaataaa
    13081 agcaaagcaa aagttatata taacaattta aaagataaaa aatcagttgg tataattgat
    13141 atagatagag aaactggaat aacaaaggta gctaaaccag ttggagtagt agcggcaata
    13201 actccttgta caaatccaat cgttacacct atgagcaatg caatgtttgc acttaaggga
    13261 agaaatgcaa ttattatcac acctcatcat aaagcaattg gatgtagtac aaaaactgta
    13321 gagatgatta atgaagaatt agaaaaaata ggagctccag aaaatttaat acaaatactt
    13381 gaccaacaat caagagaaaa tacaagaaat ttaatttcat cagcagatgt agtaattgcc
    13441 actggaggaa tgggaatggt aaaagctgcg tactcaagtg gaaaaccagc acttggtgta
    13501 ggggcaggaa atgttcaatg tatcatagat agagatgtag acattaaaga agcagtacct
    13561 aaaatcatag caggaagaat ttttgataat ggtatcattt gttcaggtga acagtcagta
    13621 atagtagcag aagaaatgtt tgataaaata atggatgaat ttaaaaataa caaaggtttt
    13681 atagttagag ataaagtaca aaaagaagct ttcagaaatg ctatgtttgt aaataaatct
    13741 atgaataaag atgcggtagg tcaatcagtt catacaattg caaaaattgc aggtgttgag
    13801 ataccagaag atacaaaaat aatagtaata gaagctgatg gaccaggaga agaggatatt
    13861 attgcaaaag aaaaaatgtg tccagttata tctgcataca agtataaaag ttttgaagaa
    13921 ggtgtagcta ttgcaaaagc aaatttaaat gtagaaggaa aaggacatag tgtatctata
    13981 cattcaaata cagttaaaaa tatagaatat gcaggagaaa atatagaagt atcaagattt
    14041 gttattaatc aatgttgtgc tactagtgct ggaggaagtt tctttaatgg tcttgcacct
    14101 actaatactc taggttgtgg ttcttgggga aataacagca tctctgaaaa tcttgattat
    14161 aagcatctaa ttaatatttc tagaattgct tattatatgc cagaaaatga agtccctaca
    14221 gatgaagaac tttggggata aaatttagac aaaaaatatt cattctaaat taaagtagga
    14281 atatatttta atttagaatg aatttaagac ataaattaaa tttaaattag tttattggac
    14341 taaatttaaa atattaagag acatatagaa gaaggaagta ttataattta aaataaataa
    14401 aaaaatctat aaaagagaag gagtggtttt attatggcat taatgacagg agctcaatat
    14461 attgaaagtt tgagaaaatt aaatactaag gtttatatgt ttggtgaaga ggttaagaat
    14521 tgggttgacc atcctatgat tagaccatct ataaattgtg tagcagcaac ttatgactta
    14581 gctcatgacc cagaatatgc agatttaatg acagttactt caaatatcac aggtgaaaaa
    14641 ataaatagat ttggtcatct tcatcaaagt gttgatgatt tgataaaaaa agtaaaaatg
    14701 caaagactat gtggtcaaaa aacagcttct tgtttccaaa gatgtgttgg tatggatgcg
    14761 tttaatgcag tgtattcaac aacatttgag tgtgataaag cccatggaac taattatcat
    14821 gataattttg taaaatactt aacttatata caagaaaacg atttagtagt tgatggagct
    14881 atgactgacc ctaagggaga tagaagtcta tcacctagtg ctcaacctga cccagatatg
    14941 ttccttcata tagtagaaag aagagaagat gggataattg taagaggagc aaaggcacat
    15001 caaactggtt caataaattc acatgagcac cttataatgc ctactataag tatgactgaa
    15061 gcagataaag actacgctgt atcatttgca gttccttcag atgctgaagg agtgtttatg
    15121 atttatggaa gacaatcttg tgacactaga aaattagaag aaggtgcaga tgttgattta
    15181 ggaaataaag agtttggagg tcaagaagct ttagtagtat ttgataatgt atttgttcca
    15241 aatgatagaa ttttcttatg tggagaatgg gatttctctg gtatgttagt agagagattt
    15301 gcaggatacc atagacaaag ttatggtgga tgtaaagtag gagtaggtga tgtaataata
    15361 ggagcagcag ctttagcagc tgattataat ggagcaaaca aagcttcaca tataaaagat
    15421 aaactaatag aaatgactca ccttaatgaa agcttatatt gctgtggtat agcatgttca
    15481 tcagaaggtc acaaaacaga agctggaaac tatcaaatag atttacttct tgcaaatgtg
    15541 tgtaaacaaa atgtaactag atttccttat gaaatagtaa gacttgcaga agatatagct
    15601 ggagggctta tggttactat gccttcagaa aaagacttta aatcagacct taaagttgga
    15661 acaagtggaa tgactattgg cgaagtatgt aacaagtatt ttaaagcttc ttcagtggct
    15721 tcaacagaag aaagaatgag aatattaaga ttcttagaaa atatatgcct tggttcatct
    15781 gctgttggtt atagaactga gtcaatgcat ggggcaggtt caccacaagc tcaaagaata
    15841 atgatttcaa gacaaggaaa cataaatcaa aagaaagaat tagctaagaa aattgcggga
    15901 ataaaaaaag aggaagcttt aaatttataa aaagttgata tataaaggga aattatatat
    15961 taatgtgtat taattaatga aaaaatatgt agtataagag atagttataa aattatggtg
    16021 gtttttagct aagtaaagaa atttttaata aggagaattt acacatgacc tgtggagtta
    16081 gattttgtgg gggctgtaac cctagatacg aaagagggaa ggctcttaca ataatcaaag
    16141 agcacttcaa tggtagggta gattttagta tagcacaaga gaacatcgag tatgatttgc
    16201 tacttataat tggaggatgc gcaactctat gcgcatccta tcaacaatat aaagtgaaaa
    16261 atgaatgtgt taagatgtgg gattttagcc atatagaaag agttataaat gtgattgaat
    16321 cagcaatttg tgaaacttaa aaaagctaaa tggggggatt tcattgagtt ggcaagaatt
    16381 gtatcaaagt aaattatgta gtgctacaga agctgtaaaa cagattaaaa acggtgatac
    16441 tgtagtattt gcacattgtg taggtgaacc tcctgcacta gtagaggcta tgattgaaaa
    16501 tgctgaacaa tataaagatg ttgagattaa acatatggta agcttgggta gtggtggata
    16561 tactgctaag ggaatggaag ctcattttag agtaaatcca atgtttgtaa gtggaaatgt
    16621 aagaaaggca attgaaaatg gagatggtga ttttacacct gcattcttcc atgaagtacc
    16681 aaagttgctt agagaaaaaa gattaaaatg tgatgttgtt ttagcacagg taactccacc
    16741 agatgaacat gggtattgta gcttaggaac atcagttgat tatacttatg aagccattaa
    16801 aactgctaga acagtaattg ttcaagtgaa tgaccagttt cctagaacct atggtgaggt
    16861 agtccatgta tcagagtttg actatatagt ggaaaaatca caacctttat ttgaactaca
    16921 acctgcaaag attggagaag tagaagaagc aattggtaaa aattgtgctt cattaattga
    16981 agatggttct actttacagc tagggattgg tgggatacca gatgcagtta tgttattttt
    17041 aactgataaa aaggatttag ggattcattc agaaatgatt tcagatggga ctttggccct
    17101 ttatgaaaaa ggtgttataa atggtaaata taaaaatttt gataaagaaa aaatgacagt
    17161 taccttctta atgggtacta aaaaattata tgactttgca aataataacc ctgcagtaga
    17221 ggtaaaacca gtagactatg tgaatcatcc agcaattata atgaaacaac ataagatggt
    17281 ttctataaat tctgctatac aagttgattt aatgggacag gtagttgcag aggctatggg
    17341 acttagacaa tttagtggtg ttggaggtca agttgacttt atacgtggag tgtctatggg
    17401 tgaagatgga aaggcaatta tagctatgcc ttcaataact acgaaaaaag atggtacagt
    17461 aatttcaaaa atcgtatcta ttgtggatga aggtgcacct ataacgacat caagaaatga
    17521 tgttgactat attgtaacag aatacggtat agcagaatta aaaggaaaat ctcttagaga
    17581 aagagcaaga aatttaataa atatagctca tccaagtgta agagaaagtc tagcagtaga
    17641 atttgaaaag agatttaagg agaaatatta ataatagagg ggtgttaata atggaagcac
    17701 ttagagtagt tccaaagata ttttactttg atacatttaa agaatttaat gaagaattta
    17761 aaataggaaa aaatgattta gtaattacta atgagtttat atatgagcca tatatgaaac
    17821 ctcttggaat agatacaaat ttaatttttc aagaaaagtt tggaacaggt gaaccatctg
    17881 atgaaatgat agactccatg acaaaggaaa tgaagaaata caattttgat agaattattg
    17941 catttggagg aggaacaata gttgatatat gtaagatatt agcacttgat gttccagaaa
    18001 agtctattga tttatttgaa ggagaagtat cacctaaaaa agtaaaagag ttagtagtag
    18061 ttcctacaac atgtggtaca ggtagtgaag taacaaatgt agctattgca gagttaaaat
    18121 ctaaacatac taaaaagggg cttgcagtag aagaaacata tgcagactat gcagtgttaa
    18181 ttccagagac agtaaaaggg ttaccttaca aattctttgt tacaagttcg gtagatgctc
    18241 ttatacatgc tattgagtct tatctttctc caaaagcaag tccatttaca gagatgtatt
    18301 ctctacaagc aataaaaatg attatggatg ggtataagaa gatagttgat aaaggagaag
    18361 aagagagatt taatcatctt agagactttg tacttgcatc aaattatgca ggaattgctt
    18421 ttggaaatgc tggttgtgca gcagttcatg cactatctta ttcaataggt ggagctttcc
    18481 atgttgcaca tggtgaagca aattatcagt tctttactga agtatttaag atgtattcta
    18541 gaaaaaaacc taatggaaaa attataaaat gtacaaaaat tttagcagat gcccttgaat
    18601 gtgaccctaa ctgtgatgtt tatggagaat tagaaaagtt tttaaataaa ttaatagcta
    18661 aaaaagcttt gagagaatat ggaatggtgg aaagtcagat agatgaattt acagatagta
    18721 caatagcaaa tcaacaacga ctacttgcta ataattatgt agagcttagt agagaggaaa
    18781 taagagagat atttgcaaat ctttattaat acaatttttt atttatatgt atagtcaaca
    18841 taaacaatgc taattatatt tatgtacaaa taaaaataag ggaacttaaa ttttaattaa
    18901 agttaagttc tcttattttt atatggagtt aaatataagt atatttttaa tttaaaatat
    18961 gcttatattt aagtctatta ctttatttga aacaatttgt agaatttcaa attccttgac
    19021 agtaataagt aagtaattgt ataatcaaac tgcaatatat taataatatt agtgaaaatg
    19081 aaaggattat aaaatatgta taaatcagaa aatttttcaa aaaaatctgt attaataaat
    19141 tcatttttaa gtaaattttt aaaaataatt ggatggggtt tggtaagctt atttacatta
    19201 tcagccttag tactttcaac tatttccatt ataattggat gggctgtaat acttcctatt
    19261 caagtatgtg cagtattttt acttatagga ggagtttgta tttttaaagg taagagatta
    19321 ggagaccaaa tttctcgtta taaaaaatat tgtacaatta taaacaatag aaatattatt
    19381 ccagtagaac ttattgcaga aaacacatct aaatcattaa attttataat aaaagatgta
    19441 caaaagatga tagacaaaaa ctactttata aatacttata ttgataaaag aaataatcag
    19501 attgtgttaa caaatgaaga ttttgttcca ccaagatatg aagatgtagc atatgaagtc
    19561 aaagaagaag aaaagactga tgaatccaat gaagttgata caattataaa taaaggaatg
    19621 aattatctaa cacaaataaa agaagctaat aaaaatatta aatcagaatc aatgggcgat
    19681 aaaattgtac aagtagaaga tgttacaagt aaaatatttg atgttgtaaa acatgaccca
    19741 tcaaaactta ctcaaataca aaaatttatg gattattatc ttccaaccac tttaaaacta
    19801 ttaaattcat atcatacatt ggaagaacaa ggaattgata gagaaaatat aacaacaact
    19861 atggaaagta ttgaaaatac aatgaatacg attgtagtag cttttgaaaa tcaattggat
    19921 tatctgtttg aagacgaagc cattgatatt tctacagata ttactgtttt agagaatatg
    19981 ttagtccaag aaggattaac gagtggtaaa ttttaacttc aatagaaaaa atattctgtt
    20041 atttttaaac aattaattag tcataaagta taaaatgtgt attatataag ttaatcagta
    20101 ctttatgaag gaagaggaga gaaagataca atgaataatt tagatgatat accagttatg
    20161 ccaactttga cacttgaccc atttggagaa gaatcaaaca ctaatgatat agataattct
    20221 gacttattaa tgaaaaagga tgaaaaagac ccagaagaag aaaaactgtc tgaatctgaa
    20281 cgcaagatgg taaaggaatt tgcggaaaaa atagatatta caaatacaaa tatgattttg
    20341 caatatggag ctggtgctca aaaaaaggta gcaagttttt ctgaaacagc tttaaagagt
    20401 gtaaaaacaa gagatttagg agaagttgga gatatgctta caaatctagt tactgattta
    20461 aaagcatttt cagcagatga aaaagaacaa agtggttttt taggaatttt taaaaaggca
    20521 aataataaaa tttcaaattt aaaaactaag tatgatagtg cagaggtaaa tgtggataaa
    20581 gtaagcaaag agcttcaaaa gcatcaggtt aaaatattga aagatatagc aatgcttgat
    20641 aagatgtatg aattgaactt agcttactca aaagagctta ctatgtatat tatagcagga
    20701 aaacaaaaat taaaggatat gaaagaatat gagatgccaa agttgagaga aaaagctcgt
    20761 ttatctggtt caacagaaga tgctcaatct gtaaatgata tggtttcact ttgtgacaga
    20821 tttgaaaaga agattcatga cttagaatta actagaatgg tatcgcttca aatggctcct
    20881 cagataagat tggttcaaaa tagtaataat ctgatggcag aaaagattca atcaactata
    20941 gtaaatacca ttccattatg gaaaaatcaa atagtgcttg ctcttggaat ttctcactta
    21001 aatcaagcta tgaaagcaca gcgtgaagtt agtaatatga caaatgagct tttattaaag
    21061 aatgcagaaa ctttgaagat gggaacaata gaaacagcaa aagaatcaga aagaggaatt
    21121 gtagatatag acacaattaa gaaaacgaat caatctctaa tatctactat tgatgaggta
    21181 gttaaaatac aacatgatgg tagaataaag agacaagaag cagaagttga attatcaaaa
    21241 atagaaaatg aacttaaaag taagcttctt gaatttacag ttaaataaaa attatactaa
    21301 tataaaaaga gactgtctca aaatagagat aagtctcttt ttcattgttt aaatgattaa
    21361 agtatattta tattataaat ttctattatc ttttaacata acatcatgag ctccaccttc
    21421 aactatacta gtagaagata caagtgtaag tttagcattt ttttgaagtt caggaatgct
    21481 aagtgctcca cagttacaca tagtagaacg aactttactt aaagaaagag ttacattgtc
    21541 tttcaaagaa ccagcataag gcacataaga gtcaacacct tcttcaaaag aaagtttctt
    21601 atctccacca aggtcatatc tttgccagtt tctagcacga gcagaacctt ctccccaata
    21661 ctctttcata taactaccat ttatattaac tttgttagtt ggactctcat caaaacgaga
    21721 gaagtatcta ccaagcatta taaaatctgc acccatagct aaagctaaag ttatatgatg
    21781 gtcataaacg ataccaccat cagagcaaat tggaatataa atacctgttt tttcaaagta
    21841 ttcgtctcta gcttgagcaa cttcaattat agaagtagct tgtccacgtc ctataccttt
    21901 ttgttcacga gttatacata tagaaccacc accaatacca actttaacga agtcagcacc
    21961 agcttcagct aggtaaagga atccttcgcg gtcaactaca tttccagctc ctaccttaac
    22021 tgtatcacca tatttttcac gaatgaaatc aagtgttatt ttttgccact cagaaaaacc
    22081 ttctgaagaa tctatacata aaacatcagc accagcttca actaaagcag gaacacgttc
    22141 agcaaagtct ctagtattaa taccagctcc aactacatat ctcttagaag aatctaaaag
    22201 ttcaagtgga ttttctttat gagaagagta atctttacgg aataccatat acataagatt
    22261 accattatca tcaagtacag gaagagaatt aagtttgtgg tcccatataa tattgtttgc
    22321 ttcctttaaa gtaacatctt tgttagcata aactatagat gacataggag tcataaattc
    22381 actaacttta gtatctaaat ccatacgact tatacgataa tcacgacttg caacaatacc
    22441 caataattta ccagttgaag ttccatcttc agtaacagct actgtagaat gtccagtttt
    22501 ttcttttaag tcaagtatgt cttttaatgt gttatcaggt ttaatatttg aatcacttac
    22561 aacaaaacca gctttgtggg atttaacacg tgctaccata gcagcttcat tttcaatagt
    22621 ttgagaaccg tatataaatg aaataccacc ttctttagca agtgcaatag ccattttgtc
    22681 atcagaaaca gattgcataa tagcagaagt caaaggtata ttcatataaa tatctgcttc
    22741 ctcgcccttt ttaaatttag taacaggtgt ttttaaactt acattagcag gtatacaatc
    22801 agtagaagag aaacctggta caagaaggta ttcactgaaa gtatgtgatg gtgtatcaaa
    22861 ataaaacgcc attttttaat cactccttat atttttatac tttttataat tgatagtatt
    22921 aattataact tattctttaa ttttattaaa gtattttgtc aaatattgag atttttgaaa
    22981 aatttaaact attttaatta aatttgttta atatatattg ccctataggg taaagttgta
    23041 tattaaataa tgtttagtgt ttaatagtag ctaatttaaa attaatcttt agtgattcat
    23101 ataattacat ttgtatagtt tacattgata atattactag agagtgcata aacctcaaaa
    23161 atacagataa attaaatcta tattagtata tccaaaagta catttaataa atttatttaa
    23221 ctgaattatt attttcactt ctattaaatt taaatatttt ataaaaatag tattatttac
    23281 aaaatcatat actccaaaat actacataaa taaaattaaa caaaaactaa aatgacaaat
    23341 gtcattatct aaagtgacat agaaacggtt tcttaaagtt gttactataa aatataaact
    23401 ctataataaa agtataacaa aagggaatca tatcgatata gaatataatt caagaggagg
    23461 taaaattatg agtagttcta atcaatcgac aataaagaca tctatacagc gagtagggaa
    23521 atttttaagt ggtatggtaa tgccaaatat aggagctttt atagcatggg gtcttataac
    23581 agcattattt ataccaacag gatggatgcc taatgaaaaa ttgagtacta taggtgaccc
    23641 aatgataaaa taccttttac cactattgat agcttatact ggtggtaaag caatagcagg
    23701 acaaagaggt ggcgtaatag gtgcagcagc agctatggga gtaattgttg gtgcagatat
    23761 accaatgttt atcggagcaa tgataatggg accatttgca ggatgggtaa ttaagaagtt
    23821 tgataaattt gtagatggaa agataccaac aggatttgaa atgttagtaa ataacttttc
    23881 aataggtata ataggtatgc ttcttgcaat actaggattt tatgcaattg gaccagcaat
    23941 agtagcaggg acagctctta tagaatctgg agttcaattt atagttagca aaagtttatt
    24001 gcctctagtt tcagtattta tagaacctgg aaaagtatta ttcttaaaca atgcaataaa
    24061 tcatggtata ttagggccta taggtatagc tgaggcaaaa gaagcaggta aatctataat
    24121 gttcttacta gaaagtaacc ctggaccagg tttaggagtt ttattagcat attggatgtt
    24181 tagtagagga agtgtaaaac aatcagcacc aggagctgta ataatacatt tctttggtgg
    24241 tatccatgaa atttacttcc catatatttt aatgaatcca gttttaatat tggctacaat
    24301 ggcaggtggg gcagcaggaa tattgacttt ttcaatatta ggagctgggc ttgtagcagc
    24361 accatcacca ggaagtatat ttgcacttat ggcactagct ccaaagggag gattacttcc
    24421 agtattagca ggagttgcag tggcaacagt tgtatcattc ttagtggcag caccatttgt
    24481 taagagagct tcagcaaatc aaagtgaaga agacagtact tctttagaag aagctaaagc
    24541 aaaaatgagt gatatgaaat ctgcaagtaa gaactctgag aaaaatattg aggaaaaaca
    24601 gcttgaagta aatgagatta agaagattgt atttgcatgt gatgcaggaa tgggttcgag
    24661 tgcaatggga gcttccagat ttaaaaatag aataaaaaac ttagacttaa atatagaaat
    24721 tacaaattca tctgttgata atcttccaga tgatacacaa atagtagtaa ctcacaatac
    24781 attagttgaa agagttgcta agaataattc aagtgttgag atagtttcaa taaacaattt
    24841 tttaaatgac ccaaatttag atgcattatt taaaagatta gaatctaaat aaaaataaaa
    24901 agtaccacta attaggagtg gataatttga aaaaaaagaa gattacatct aggcaaaaaa
    24961 agataatact aatgatagta gaaaattcaa agaaaaacat tccaataact atttctgaga
    25021 ttgcagggac tttagagtta agttcaagaa ctgtacttag agatatgtct ggaattgaaa
    25081 aatggtttga tgaaaatgat tttaactttg taaaaaaacc aggagtggga ttgattttag
    25141 aggaaaatat agaaaatcaa aactttataa ttgagttgtt agaagaagaa aaaatagaaa
    25201 aagaatacag caaggaagaa agaaatttaa ttatattatc aaagctacta gtttctaacg
    25261 agccagtaaa atcctattat tttgcaaaaa tattaaaggt atctgaaggg gtacttaata
    25321 atgattttgc cttagcaagt aaatggttgg aaagatttga tattgagctt gttagaaaac
    25381 cagggcttgg tgtctactta aaaggtcaag aaaaaaactt tagagaggca tatgtaaatc
    25441 ttatatacga ttcattcaat gaaaaagaaa tactagatat ggtcagaaat ataagtgaaa
    25501 atatacaaac agataaagca atagaaattt taagtgaaaa tagactttta aatttaatgg
    25561 acaggtgcat aataagaaaa gttgaagcta cattaacaaa gaagctttca gatttagatg
    25621 taaatttagc tgatagtgca tatatagggc ttgtagttca tatttcatta gccttacaga
    25681 ggataaaaaa tggtgaaaat ataactatgg ataaagagtt tctaaaagaa ttatctataa
    25741 cagaagagtt taaattagct aaagaaatcg taaaaggtat ggaaacagat tttaacatgg
    25801 atataccagt agatgaggtt ggatatataa ccatgcatat aagaggtgca aagcaaaggt
    25861 catcttcaaa ccataaggct ttaaacttag atgatataga aataatggaa attacaaata
    25921 agatgataga tttggcggaa gatgaattta aaataagttt aaaaaatgac gagaggttat
    25981 ttaaagacct agcaaatcac ttagggcctt ctataaatag attgaatatg ggattagaaa
    26041 taagaaatcc tcttttagat gaaataaaaa gcaagtattc atatgcctat gatggagttg
    26101 aaaagatttc tagaattata aaagataaac taaatataaa ttcaatacct gaatcagaaa
    26161 taggatatat tgcaatgcac tttgcatcag ccatagaaaa aaatcttatg atgaatacta
    26221 atataaatat tgttgtggca tgtcccactg gaataggtac ttcaagattc ttatcaacta
    26281 agattgaaaa taaatttcct aatttaaata tacttgaaac catatcagct ataaacatag
    26341 atgaagagta tttaaaggaa aaagatgttg atttaatagt gtctacagtt gagttaaata
    26401 caagtttaaa ttatatatgt gtaggtccat ttatgagttt agatgatgaa cagataatca
    26461 aggaaaaaat aaaatctata gctcaaaata aattaatcaa tttaaatgcg aaaaatgata
    26521 ctaagagtaa gaataaagta tatgaacaga taacagaaag tatgaatata ggaaaagata
    26581 ttcttcaatt tttagaggaa attagatttg aaaaatttga aagtaaagat ttaagtgagc
    26641 ttattgaaga ctcatcaaga atatttgcaa aatctagtga agatataatc tctataaaag
    26701 aatcgttaaa agaaagatta aaaatctcaa ttccatatat agaagaatca aaaattctat
    26761 tgttacattg tatgagtgaa agaatagata ttatgaagtt atcaataata aaactagaga
    26821 atagaatcgt gctagattca aatgaagaaa tcgacaatgt agtttttatg ttacttccta
    26881 aaaattcacc aagttatcaa agacaaataa tgagtgaaat aagtggttca ttaatagaca
    26941 atataatttt tactaataag ataaataaat tctctataga agagatggca ttagaggtaa
    27001 aagatatagt ttttaatttt tatacaaaca gattaaaagc atttatagat aaataaaatt
    27061 aatattaaaa aggaaggttg atactatgag taaagtattg aatgagaata atatattttt
    27121 agggttagat agtgtttcaa aggaagaagc tataacttta gcaggaagaa aattagttga
    27181 aaatggatat gtaaaagaag aatatatacc agcaatgtta gaaagagaaa aagtaatgac
    27241 tacatatatg ggaatgggag ttgctattcc acatggtgta aatgaagcaa aaaaagaaat
    27301 attatcttct ggaatagtta tattacaatt ccctaatggt atagattttg atggagaaaa
    27361 agcatattta ttaataggaa tagctggtgt tggagatgaa catttagaaa tactatctaa
    27421 tatagcagta gttttagatg atgacttaac agaaagacta aaaaattcaa atgacaaaca
    27481 agcttttatg gaagcttttg ccaactaatc ttaggaggga tttaaaatga aaaaggcaat
    27541 tcagtttgga gcaggaaata ttggaagagg ttttattgga ggcttgttag ttaagtcggg
    27601 ttatcatgta gtatttgctg atgtaaatga ggatatatta aactcaataa acaaagataa
    27661 aaagtatact atacacataa gagatgtaga atgtatagat gaagtaattg ataatataag
    27721 tgcggtttca tctataaaag aagaaataat agatgagatt gtacaggctg aaataataac
    27781 tacagcagtt ggacctttag ttttgactaa aatagcctct acaattgcaa aaggtataaa
    27841 ggctagaaaa gaaaagggat taacaagtaa tctaaatata atagcatgtg aaaatgcaat
    27901 atacgcaagt tcttctttaa aagaagaggt acttaagtat ttaaataagg aagaagtaga
    27961 atatttagag atgtatgttg gttttccaaa ctgttcagtt gatagaatag ttcctcctgg
    28021 taaaaacgaa aatcctcttg atgtaacagt tgaaaatttt tatgagtgga atgttgaaaa
    28081 acaaggattt aaaggggaaa taccaactat agttggaatg aatttagctg ataatcttat
    28141 ggcttatata gaacgtaaat tgtttacact gaatacaggt catgctataa cagcttatat
    28201 aggatattta aaaggatata agactataga agagagtata aaagataaat ttatctgtga
    28261 tatagtcaaa agtgcaatgg tagaaagtgg agaaggattg attaaaaaat acaattttga
    28321 ctcagaagtg cactataaat atattgataa aattttaaat agatttaaaa atccatatct
    28381 taatgatgat gtattaagag tcggaaggga accattaaga aaactaagtg ataaagatag
    28441 attgattaaa cctttaatga cagcaaaatc atatggatta tcagttgata atttgattct
    28501 tggaataggt gcagcgcttc attataataa tagtgaagat actcaaagtg tagaattaca
    28561 agagttgata aagtctattg gggtaaaaaa agccgttgct aaaatagcta atataagcaa
    28621 tgacgaagaa cttttaaata atatcgaaaa aagttatata tttatgaaaa atttataaat
    28681 ttacttgaaa aaaagtagtt ctgataaagt aactataata gattattcta cacagtttga
    28741 attatttgtt gaataataga gaattataat atataattaa aaggaataaa ttaatatatt
    28801 tacctgtata tgtttgataa tatggttcaa atgtttctac taagctacca ttaatagctt
    28861 gactacagga gtgaagaaga tatagtttat acttatttta aattatatat taagttaatt
    28921 actttgaatt ttaagctcct gtctatgata tagacaggag cttttttagt attttaatat
    28981 aaaatactta caagaataga tagcaaaatt agaacaaata taattttttt attaatataa
    29041 ttttagaaag ggctaggtgg aagttcaatg aaggctttac aagaaaagat attgagagaa
    29101 ggcagtgttt caggaaatga tatactaaaa gttgatagtt ttttaaacca tcaaattgat
    29161 gtagcttttt taaatgaaat aggaagagaa tttaaagaga gatttaaagg agaaaaggtg
    29221 gataagatat ttacaataga ggcttcagga atagctatag catcaattgt ttcacagtat
    29281 tttgataatg cacctgtagt atttgcaaaa aaatcagaat ctaaaaattt ggataaagat
    29341 gtatatgaaa ctaatgtata ttcatttact aaggcaagag agtattcagt taaagtttct
    29401 aaaaagtaca taaacaaagg cgaaaatata ttgatagtgg atgatttttt ggcaaatgga
    29461 agagctgctc ttggacttaa agatttaatt gagcaagcag aagctaactt agttggagta
    29521 ggaattgtca ttgaaaaagg atttcaagct ggaggagcac ttttaaaggc taatgatgta
    29581 agattagagt ctttggcagt agttgaatct atagataatg gaactgtaaa atttaggtaa
    29641 tttatgatat tatatacttg tgtttagcac atattttaac tatgtaatta tggaggattt
    29701 tttatgagat tttttataga cacagccaat attgaagaaa taaaagaagc aaatgattta
    29761 ggtgtaatct gtggtgtaac tactaatccg tctctaatag ctaaagaagg tagagatttt
    29821 atagaggtag ttaaagaaat aagtgaaata gtagatggac caataagtgc agaagtaata
    29881 agtttagaac ataaaggtat gatagaggaa gcagaaaaat tatctaagat acataaaaat
    29941 atagttataa agatacctat gacagcagaa ggtctaaaag cggtgaaagt actatcaagt
    30001 aaaggtataa agactaatgt aacacttata ttctctgctg gacaagctct tttagctgct
    30061 agagctggag ctacatatgt aagtcctttt gttggtagat tggatgatat atcacaaaat
    30121 ggtcttgatt taattgaaga aatcgttgat atatttagtg taaatagtat tgaggctcaa
    30181 ataatagttg ctagtgttag aaatccaata catgttttac aagctgctag aatgggagca
    30241 gatatagcaa cagttcctct taaagttata aaccaaatga ttaagcatcc tttgacagac
    30301 aaaggaatag atagctttat gaaggattgg gaaggtgctt ctttaaaatt ataattataa
    30361 actacgcttt ataagtatat taaagaggtt attatggaaa ttctaagtaa taaggctagg
    30421 ctattttgcc tagtcttatt ttggtgtata atatattgaa acatattatt gaaatagatt
    30481 aattttttaa gtgaggaggc gaaaaatgga taaaatatta agagagatac aaagagaaga
    30541 taaaaaaaat ccatatactg accaagaact tgctgaaatg ttaaatgtag ctaggtctga
    30601 agtgatatca gttaggaaaa aaaataatat tttagattcg agagaaagaa gaaaaaaaat
    30661 attaataaaa gatatatcaa aaattgtaag tgaaaatcct caaatgtctg aaagaaaaat
    30721 aactgaaata ttaatagaaa atggatataa tatatcgaga agtgcagttt caaaattatt
    30781 aaaagaggaa aatttaaatc agtcaaagat tgggattaag gataaagacc cagcatcatc
    30841 aggaaagtat gtgaaggtga gtaaagttgt agaagaagat ggatttgaag aattgatagg
    30901 tataaaggga agtttgaaag aaaaggtaaa tctagctaag tcagcaataa tgtatcctcc
    30961 taatggcctt catactataa tatatggaga aacaggagta ggtaaaagtg aattagctac
    31021 atgtatgtat aaatatgcta taaaaaacaa cattaaagaa gagaacagcc catttatagt
    31081 gtttaactgt gcagactatg cagaaaatcc taatctattg atagctcaac tctttggggt
    31141 agtaaaaggt gcatatacag gagcagatgc aaatagagaa ggtcttgtag aacaagctaa
    31201 taatggaata ttgtttttag atgaaattca tagattgcct gctgctgggc aagaaatctt
    31261 attttcatta atagatagag gagaatttag aaggttagga gaaagtagtt ctaatagaaa
    31321 ggcaaatgtt ctcataataa gtgctacaac agaaaatcca gattctaatt tacttcaaac
    31381 atttagaaga cgtataccaa tggtaataaa tttacctaat atgagtgaaa gaccaaaatc
    31441 tgaaagatat gaaataataa taaagttttt tgaaagagaa gcaaagcgag taaacaagaa
    31501 ttttataata actaaagaag ttatgtgtgc acttatgaat tataagtgta ctggaaatat
    31561 aggtcagtta aagagtgata tacaagtaac ttgtgctaga gcttttagta aatcgatatt
    31621 ttctagcgat aaggtaatta tagatttaga tagtttaagg gattatataa aaagtggata
    31681 ttatgattgt aattgtaaaa atgaaaagta ttctgagttt tcagttgagg atatatatat
    31741 agatattagt gaattggtga gtggaaaaaa tagaatttta tctgataatg agataagcga
    31801 gatatataat tatgcagaaa aagagcttaa ggttttggaa agtaagtgct tttcagaaga
    31861 agagttaaaa aatgcattta tagaaaagtt agataagaag tttaatgcta ttaaaaacaa
    31921 taaaaattta tctgatagaa gaagtcgaat agactgggga ggacaattaa aagagtctac
    31981 actggagata atggataagg taattgtatt tattaaggag cagtttaagc atgtaaatca
    32041 aggtctgtac ttggctctag caattcatat tgagcatgct ataggtagga taaaagatgg
    32101 aaaaactata ataaatccga gtttagataa aataaaagca tcaatgccaa tggaatatga
    32161 gttgtcaaga tatataatgg gtatagtaga agatttgaca caagtaacat ttccagaaga
    32221 tgagcttgga tatttggctt attatataaa taaattttgt tataatgagg aaagtataaa
    32281 agataaagtt aaagtagtaa tagttacgca tggtaaagtt ggaattgaaa tgtctaaagt
    32341 tgtaaatcat attttaggta tagaatgtac actaggtata gaaatagcac ttacagattc
    32401 accatcagag gggatagagc atgtattaga agaacttcaa aagatagaag ctagaaaagg
    32461 tattctagtt ctaattgata tgggttcttt ggtaattctt ggtgatgagg ttgaaaaaag
    32521 gcttggaatt agatgtaaaa ctgtaaatag agtagataca ttattggcaa tggaagcagg
    32581 aaaacttgca accattgaag ggaaaagttt agatggtata atagctgatt taaagaaaaa
    32641 taagaattat gctatgataa atacaaataa atttagttac agaaaaaacg agtatggaaa
    32701 gaaaaatgta atcattactt tatgtttgag tggtgtaggt acagctttaa atttaaaaga
    32761 gcatatagaa aaacaaatta aggaatatga cactttaatt gaagtaaagc cagttgcttt
    32821 tttaaataat aatttagaag aagagttaaa tgatattgaa tctgaatata atattattgc
    32881 tatctgtgga actattgata tagattataa aaacgtgcct tttatttctt ataatgaggt
    32941 acttggtaaa aatggtatta ataaagtatt agagcattta aatagtaaac aaccagcttt
    33001 aaatattgaa aaccagttga ataatttaat acatgaagat ttgattttat acaattttga
    33061 aggaatttca aaggagtata taattgatac tcttgtttca aaacttgaag aaggtggata
    33121 tgttgactca aagtatatat taagtgtata taaaagagaa gcaatgggaa gtgttgtaat
    33181 ggcctctaag gtagccgtgc cacatggact tccagaaaac gttataaagc ctgcaatagc
    33241 aatcgcgagg ttgaataaac ctatagtatg ggacaataaa tttatggtgg atttggtggt
    33301 actactggca cttaaagaaa ataataagaa agaaatacga agcttatttt caaagattaa
    33361 tgaccagcat actttagaag ttttattaaa tactgaagat aaaaatgaaa taaaagaact
    33421 tttaagctaa ttattagtac cgagaagaaa gacaaaaaaa tttgctttag tataaaattt
    33481 aaaactactc aattgttaag tagttaatta ctctatataa ggctagttct atgaaattta
    33541 tttatatgat tttatagaat tagctttttt cttggtaaat aaaatatatg aatttattta
    33601 tgtaaaaagt aaattttatt ggacaattct atgagaa
//
LOCUS       DAEQAF010000038        33550 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.039, whole genome shotgun sequence.
ACCESSION   DAEQAF010000038 DAEQAF010000000
VERSION     DAEQAF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33550
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.039"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            142..984
                     /locus_tag="KRN00_001868"
     CDS             142..984
                     /locus_tag="KRN00_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBH1827734.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            999..1463
                     /locus_tag="KRN00_001869"
     CDS             999..1463
                     /locus_tag="KRN00_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827735.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            1450..2622
                     /locus_tag="KRN00_001870"
     CDS             1450..2622
                     /locus_tag="KRN00_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1827736.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKISFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            2666..3601
                     /locus_tag="KRN00_001871"
     CDS             2666..3601
                     /locus_tag="KRN00_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBH1827737.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKFPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(3875..6568)
                     /locus_tag="KRN00_001872"
     CDS             complement(3875..6568)
                     /locus_tag="KRN00_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH1827738.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVEPEVAYVVTDMLESVITEGTGGVAALPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDNGGNNGGGSTTPPDGGGTPAT"
     gene            6782..7480
                     /gene="yunB"
                     /locus_tag="KRN00_001873"
     CDS             6782..7480
                     /gene="yunB"
                     /locus_tag="KRN00_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBH1827739.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(7692..8699)
                     /locus_tag="KRN00_001874"
     CDS             complement(7692..8699)
                     /locus_tag="KRN00_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBH1827740.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNKPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            8927..9811
                     /locus_tag="KRN00_001875"
     CDS             8927..9811
                     /locus_tag="KRN00_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1827741.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            10013..11563
                     /locus_tag="KRN00_001876"
     CDS             10013..11563
                     /locus_tag="KRN00_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1827742.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            11592..12239
                     /locus_tag="KRN00_001877"
     CDS             11592..12239
                     /locus_tag="KRN00_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBH1827743.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSILLFVMYKLCKSLSIKIFQC"
     gene            complement(12381..12641)
                     /locus_tag="KRN00_001878"
     CDS             complement(12381..12641)
                     /locus_tag="KRN00_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBH1827744.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFKYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            12858..14141
                     /gene="hflX"
                     /locus_tag="KRN00_001879"
     CDS             12858..14141
                     /gene="hflX"
                     /locus_tag="KRN00_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH1827745.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYADLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDVDLDEEDFNIYREYILEK"
     gene            14149..14826
                     /locus_tag="KRN00_001880"
     CDS             14149..14826
                     /locus_tag="KRN00_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBH1827746.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            14912..15355
                     /locus_tag="KRN00_001881"
     CDS             14912..15355
                     /locus_tag="KRN00_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1827747.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            15660..16304
                     /locus_tag="KRN00_001882"
     CDS             15660..16304
                     /locus_tag="KRN00_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBH1827748.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVVVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(16390..16767)
                     /locus_tag="KRN00_001883"
     CDS             complement(16390..16767)
                     /locus_tag="KRN00_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH1827749.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(16767..17153)
                     /locus_tag="KRN00_001884"
     CDS             complement(16767..17153)
                     /locus_tag="KRN00_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBH1827750.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            17332..18087
                     /gene="nadE"
                     /locus_tag="KRN00_001885"
     CDS             17332..18087
                     /gene="nadE"
                     /locus_tag="KRN00_001885"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBH1827751.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            18170..18889
                     /locus_tag="KRN00_001886"
     CDS             18170..18889
                     /locus_tag="KRN00_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1827752.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(19056..20060)
                     /locus_tag="KRN00_001887"
     CDS             complement(19056..20060)
                     /locus_tag="KRN00_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBH1827753.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            20326..21222
                     /locus_tag="KRN00_001888"
     CDS             20326..21222
                     /locus_tag="KRN00_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBH1827754.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREMNLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            21360..22622
                     /locus_tag="KRN00_001889"
     CDS             21360..22622
                     /locus_tag="KRN00_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827755.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            22698..23891
                     /locus_tag="KRN00_001890"
     CDS             22698..23891
                     /locus_tag="KRN00_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH1827756.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            24520..25314
                     /locus_tag="KRN00_001891"
     CDS             24520..25314
                     /locus_tag="KRN00_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH1827757.1"
                     /translation="MESVMENLNNLKVELKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            25409..26749
                     /locus_tag="KRN00_001892"
     CDS             25409..26749
                     /locus_tag="KRN00_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1827758.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNTKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            26886..28118
                     /locus_tag="KRN00_001893"
     CDS             26886..28118
                     /locus_tag="KRN00_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBH1827759.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELINILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            28158..29300
                     /locus_tag="KRN00_001894"
     CDS             28158..29300
                     /locus_tag="KRN00_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBH1827760.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            29311..30105
                     /locus_tag="KRN00_001895"
     CDS             29311..30105
                     /locus_tag="KRN00_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1827761.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            30116..31138
                     /locus_tag="KRN00_001896"
     CDS             30116..31138
                     /locus_tag="KRN00_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1827762.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            31237..32613
                     /locus_tag="KRN00_001897"
     CDS             31237..32613
                     /locus_tag="KRN00_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBH1827763.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(32945..33289)
                     /locus_tag="KRN00_001898"
     CDS             complement(32945..33289)
                     /locus_tag="KRN00_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827764.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
BASE COUNT        12442 a         4110 c         6145 g        10853 t
ORIGIN      
        1 aatatttttt tgattcataa ctaaaagtat ataaaaatga tgaataaata tatattatac
       61 attatcaatg ataggttata taataaaatc actaacaatt atattataag aaaattataa
      121 aaattacaag gaggtataga aatgaaagaa aaagcaggga ttagaaatgc cataatagca
      181 gcctttataa tcacaatatt ggcagaatta attggaccta tttcatttaa agttatggga
      241 attaatgtaa ctttacttag tatactatgg gctatattca taggaatggc tgtttctcct
      301 catttattag ggagagttat accagcctta aaaaagttta taggggataa tgaaataaat
      361 gtatctccat atttattatc tttgacacta tatccattag ggataatgtt tggaattaat
      421 gcagggccta aagttggtat attacttcaa gcaggaccag cacttttatt acaagaattt
      481 ggtcatatgg gtacaatgtt gatagcatta cctgttggag tagcattagg tcttggaaga
      541 agtgcattag gtggtacttt ttcattatgt cgtgacacag cactaggaat tattggagat
      601 aagtatggat taaactcacc agaaggtata ggaacactag gaacttacat aagtggtagt
      661 atatttggaa cattattatt ttcattttta gcaccagtgg gtgtactttt aggatttcat
      721 ccatatgctt tagcaatggc atcaggaatg ggtagtggtt caatgatggg agctgcaaca
      781 gcatcattaa tgaatacggt tccacaaatg tcagagcaga ttttagcata ttcagctact
      841 agtggattga ttacagctgt tactggaata tatatagaat tattcttatc tttaccagta
      901 gccaactact attatagcaa agtagctcca gttattgaaa gatttagagg aagaaaaaca
      961 agaagaacaa gtaataaatt gtaaaggagg atatatatat ggaaaaaact tttaagacta
     1021 ttatggagca gataaaaata gtattgttta tatatattat tatttgcttt ggacaaatga
     1081 tagcactcaa gactcaggct caagatttgt tgattggaag tgtatctgga tttttgttag
     1141 tgataattgc tattataata aagaattttg ttaaaaaacc taatttacca ggttttgcat
     1201 gggctacatt agttgcattc gttttatcgc ttccaatatc tccagtgggg gatatcatag
     1261 caacaaatgt agggaaaatc aattttatgt ctacagtaac accattatta gcttttgcag
     1321 gaatctctgt aggtaaccaa ttagatatat taaagacttt gagttggaag ttagtagtta
     1381 tatcatttat agttatgaca tctacttact ttggttctgc ttttatatct caaacagttt
     1441 taagattaaa tggaatgctt taaggaggta gtaaatatga atgaattaaa agcaaaaatt
     1501 aaagaggaaa taaagttatt atctgaagag aaaaagatat catttgaaaa agtttctgac
     1561 tatttatttt caaatccaga attagcattt gaggagtata agtcacaaaa agcattatgt
     1621 gatttgttag aagaaaatga atttaatgta actaaaggtg taggaggatt agaaacatct
     1681 tttgaagctg tgtattcaaa tggaactaat gggaaaacag ttgctttttt agctgaatat
     1741 gatgcacttc caggaatggg acatgcatgt gggcacaata tcatagggac aagttctgtt
     1801 ggtgcaggta tcatattaaa agaaatcatg aaaaaacata atatagaagg gactgtaaag
     1861 gtttttggaa cacctgcaga agaaagagta ggtggaaaaa taactatgat taaagaaggt
     1921 gtatttaata atgtagatgc tgcattaatt ttacatccaa gtgatgcttc aatgcctgat
     1981 gatatatcat ttgctcaagt taatttaaaa tttgatttta ctggtaaggc atcacatgct
     2041 gctgcttttc cttgggaagg gaaaagtgcc ttaagtggag taatagcact atttaacagt
     2101 gtaaatagca tgagattaca tcttaaagat tatgcaagag tacatggaat tataactgat
     2161 ggaggtagca tacataatat aattcctgaa aaatctacag ctatatttaa tgtaagagct
     2221 ttaagcatag aatatttaaa tgagatttgt gaaatgctta aaaattgtgc taaaggagct
     2281 gcaatttcta ctggaactaa tgtagaaata gttcaattag atgaaatata caaagagatt
     2341 aagaatgatt ctgaattagt gaatatagtt agacaaaatt ttgaagtttt gggtgaagac
     2401 tatgttgaaa gagatttaag tcaaggtata ggttcaactg atacaggaaa tttaactcat
     2461 gagatacctg caatacaagc atatataaaa ttaaaagaaa atactgcaac tcatacagat
     2521 gaatttgctg ttgcagctgg tggtgaagaa ggcagagtag cacttataaa agcaattaag
     2581 gtgttagcaa tgtgtggagt agatattttg tatagtaaat aatatataat tttaaaatat
     2641 attaagaaag gaaatcggat tagacatgat attaaaacaa gtaatagagg tttatgacat
     2701 tttagataaa gcaaatgcta atggggaaga agtaaaaact tacttacaag gttatggtga
     2761 agtagatgta actgtaaaag aattgtcctc aagtaaaggt tcaacagatt tagtgaagct
     2821 tacaattcct ggaaaaaatg gaaaattaaa aggtggagat gctcctactc ttggtatttt
     2881 aggtagacta ggagggattg gagcaagacc agaagttata ggttttgtct cagatggtga
     2941 tggagcattg gtagcaattg cagtggctgc taaacttttg gatatgcaac gaaaagggga
     3001 catattagat ggtgatgttg taatttcaac tcatatttgc ccagatgctc caactaaaga
     3061 acactatcct actcctttta tggattctcc aattgatatg atgactatga atgaaaatga
     3121 agttgatagt agttgtgatg caatactttc tatagatact actaaaggaa atagagtaat
     3181 caatactaga ggatttgcaa tatcgccaac tgttaaagaa ggctacatat taaaaactag
     3241 tgataacctt ttagatatta tgcagactgt aacagggaaa tttccatttg tattcccttt
     3301 gtctattcaa gatataacac catatggaaa caatctgtat cacttaaata gtattttaca
     3361 accagcagta gctacagatg caccaatagt aggagtagca attacaacag agatgcctgt
     3421 tgctggatgt gctacaggtg caactaattt tagtgattta gattcagctg ggagatttgc
     3481 aattgaagtt gccaagctat ttggtagaaa taagtgtgat ttctatgata aagaagagtg
     3541 ggaaatgctt attaagagat atggcaaatt aaatagattt caaacatttg gtatacaata
     3601 attagaaaaa tattaagttt atataatttg tgatacaact atttaagaat atataaacaa
     3661 ttaggaataa aagtaagaat aaagcactta gttaaaaact ttaaaaataa aatatttatt
     3721 tgtttatata aaaaggagga ttctggttat tgggattctc ttttttatga atacaaataa
     3781 tatattgtaa ttataaaaaa aggagcgttt caaagtgatt tttttaatca ccttgagaca
     3841 actccttata tttttattta aattctattt tttattaagt tgctggagtt ccaccaccat
     3901 caggaggagt agtagagcca ccaccattat ttccaccatt atcaggagga gtagtagagc
     3961 caccaccatt gtttccgccg ttatcaggag gagtagtaga gccaccacca ttatttccgc
     4021 cattatcagg aggagtagta gagccaccac cattgtttcc gccattatca ggaggtgtag
     4081 aaccgccacc attatcacct gtgttattat tgttattatt attttcttct ggttggttat
     4141 tgtctggttt ttttgtatct tcagatgatg gttgagaact tactttagta ggagcagtac
     4201 cttcaataaa tgctgcttta gagccagaag attgctttcc tccatcctct aaattaattt
     4261 ttgtaaaata tacattttta ggaacttcaa attcagtaac cgttaaatta gcatgtattt
     4321 tttccataat tttttcccat agttttgcag tactagtact tccatgtggt acttctctac
     4381 gttttatagt gttaccagaa tcatcttttc taccagcatc atctccaata taagttgcac
     4441 caacataata aggagtgtaa ccgacaaacc aagcatcata tgcactattt gtagtacctg
     4501 ttttacctgc tacaggcatt ccctttggaa gtgcagcaac accaccagta ccttcagtaa
     4561 ttacactttc taacatatct gtaacgacat aagctacttc gggttctaca actttatgtt
     4621 cctcaggagc atttttaact aataattgac catcaaaggt agttatagta gtaaaaatag
     4681 aaggttctac ataaataccg tgatttgcca atgtaccata agcagcagcc atttgaagtg
     4741 gagtaatacc attcgccata ccacctagtg tcaatgatgg gaattttcta tcacttgctt
     4801 cagatgaacc tgagtgatta ttctttaaag ttgttatacc aaagttcttt aagtaatcca
     4861 tcattatatc tacacattca tcataagagt ctccaagcat ttcagcagtt ttgacagcta
     4921 tcgtgtttga agatttagca agtgctttac gtaaactcat agaaccatga ccagcagtag
     4981 tagttcttgg attccattta ttattttctt caaacttata tcctcctcga gaatcactta
     5041 gagcagttgc ttgtgttatt tttagagtat caatagctgg cgtatatatt gctaaaggtt
     5101 ttatagaaga acctggctga tgagggttag tagcacgatt taaagttttt ctaccactta
     5161 tatttcttcc tccagctagt gctcttattt caccattttt ataatctaag attaccattg
     5221 cagcttgcgg ttggctaact ccatcaggac cgaccatatg tcctgggaaa ttgctatttc
     5281 tatcaaattc ttcttctaaa gcatcttgca ttttagggtc tatagttgtg tttacaatta
     5341 gaccaccatt gtagaataag ttttgagctt catcatttgt atgtccttgt tccattaaag
     5401 catttataac ttcactttcg ataaggtctt ctacagatga agaaacttta tctgatgatt
     5461 gaggcaattt tatttctatt ttagctttga ttgcttcatc atattcactt tgttttatat
     5521 atttcaattc taacattttc tttaaaacaa tttcttgtct ttttttagct tcaggattac
     5581 ttacagcctt tctaacaact aatgtacctg cttttaattg tctataagta tcattagata
     5641 taagctccca agattttatt ttttcaatca tatcaaagtc cacttgagta gggtcatcta
     5701 aatcatcatc agttgtgtta acaaaaaata ataatttatt ctctaaatcc tccttagttt
     5761 catttccctc taacttagaa gttttatagg ctgaaaatct tgatggattt ttagttgaac
     5821 cagcaagaag tgctgactct gctagagtaa ggtcagctgc tgacttatca aaataaccac
     5881 gtgcaccagc ctcagcacct gctagacctc taccaacgaa gaagttattt aaataagttt
     5941 ctagtatttt atctttactt actgttttac tcatctcatg tgcatagtaa atatccttta
     6001 ttttacgagg tatagtttgc tgttcagttg ttaacagcat tttggatacc tgcataggaa
     6061 tagtactacc accttgctta gtacctgtaa gggtctttaa tactgaccta aataaacctt
     6121 taatatcgac acccttatgc tcataaaaac gctcatcttc tattgcaatt acagcatgtt
     6181 gaagataagg ggaaatctta tctaatggaa cgggtgtctt tttatttaca cttggagctg
     6241 tagataatgt ttttccatta gcgtatttaa tagtagttgt ttggttcgtc tgtttatcta
     6301 aaacagcttc tgtaactgga gttacatctc ttagtgacgc aaatactaga ccagcagtac
     6361 ctgctgtacc aacaactagt aaaactaaaa atactatccc aaatactctt agttttttaa
     6421 atttatcgct ttttttagat tttttcttgt tttttgttga acgagtcttg ttagctgaag
     6481 ttctattaat tggtttattt gtattaccag atgagctaac tttttttctc ctgattttat
     6541 ttccattttt atcattatcg ttattcataa gattttaacc tccttactta atgcaatatt
     6601 ataacacaaa taggagtagt tttgtaatta atagaaaaaa tgaatttgct ataatattct
     6661 gtacattgta tatgtataaa cgtaatatat taaaaagtct atatttttat tttatttatt
     6721 tttgacaaat attataaaaa ttatgccaaa gctacatata aataaatagg aggggataat
     6781 tttgaataga atagtagata gaaaaacaaa aaatgaattt agaaaaatca tagctatttt
     6841 tttagtaatt cttttcttgt ctgtatttat aggcagtttt atatatatag ataaaacttt
     6901 aagaccgaca ataacagttt tagcagagac taaagctctt gaactagcaa ataggtcgat
     6961 aaataaagct gttgctgaga tggtagaagg aaaaataaat tatgaagatt taatggatat
     7021 acaacttgat aataatggta aaataactat gatacaagca aacactataa tgatgaatga
     7081 aattgcatct gcaatagctt tagaaataca agatgaatta aaaaaggata agacagcaag
     7141 ttcttacata cctataggaa cagcattagg aagtcctata ttagctaaat acggtcctaa
     7201 acttgaagta tctattgaac ctataggaac agtatcagta aactttaaaa cggaatttga
     7261 gtcttcaggt ataaatcaaa ctagacatag aatatattta gaagctcaaa cacaagttaa
     7321 agtagtaata ccacttataa cttcaacaaa acaaattaaa gctcaaatac ctatttgtga
     7381 aactataata gtaggtgatg ttccagaaag ttatgtaaat attccagaaa aaaatctagg
     7441 aaatgtttta cctaacactg gaaagaatac caacaagtaa tataaagttg tatattttta
     7501 aataaattca aaataatagt ttataaataa aatttttgga aataatatta atataatttt
     7561 aataaaaatt tatattttat actatgtaaa atatctaata tatttggtct gtaggttaaa
     7621 taaaagtacc tttagaccaa atatattatt aataacttaa taacatctta aaacttattt
     7681 atttatatta tttacaacat ccatttaata aatacaccat aacctacagc tgggtcgttt
     7741 tcaattgcat gtgacactgc tccgattatt ttattatctt gaactattgg agtaccactc
     7801 ataccttgta caataccacc agtttgagct aaaagctttt tatctgtaat tttaatttta
     7861 aaacttttac tttctggatg tttttggttt tctatatcta taatttcaat attatatttt
     7921 ttacacttat taaagttatc ttgtaaaatt atttgagctt ttcctaattt aacttcatct
     7981 aaagatgcta ctttatattt ttttaacttg gaaatatcaa agttattaat ttgacctctt
     8041 attccaaaat cagtattttc tgtaaagcta ccaataatat tttctcgttt tgcatttata
     8101 catccaacac tacctttata agatttttct atattaaggt gcttagttgt agaaattgaa
     8161 cctgttttaa taggtatttt tcttgcatta ccaacactta ttggatgacc tacagctcca
     8221 aactctgatg tatctggatt gatatacgtt aaagtagcaa atccagaaag taaattgtta
     8281 aaactaattt tttctaatat gtgtttggta gttttcattg ttataagttg tccacctcta
     8341 tttaataaaa tagatacttg tttttcttct ggtaaagcat ttaaggtatt ggcaaagtca
     8401 ctatatccat caacttcagc attatttacc tttactatag catcacctaa tctaaatgga
     8461 gatgcttctc caggatttct aactatgata ttttttaatt ctgcgtcaat ttgaagtacg
     8521 tttccaattg gtattaaata ttcaggttta tttttttgta aattttgtgc ataaattaaa
     8581 ttatttgaga aaaaatataa taaaaataaa aatgttaaaa caattgtaaa ttttgactta
     8641 gctaagttgg tttttttact taaagtatta tttttaaaat gaaaattttt aagttgcata
     8701 aaacacctct ttcttattaa attattttaa taatagaatt gaagttttct tgctgcttct
     8761 atattatgtt gtgcaagaat catgttttga tgcttggaaa actagctcaa taacacctta
     8821 gttttcataa aaataaataa aataaatagt gtatatgata aaataaatac atattcatat
     8881 aaataaaaat aaacaataac tgtctagcat aagaaaggag caaaaaatga aaaaatatag
     8941 attgttagtt acttgtataa ttgccatggg aatcataatt ataggaacat caaatccagt
     9001 tagcaatttt tacaagacta caaatttgat tagttcagga aatatcacaa atgaaaaagc
     9061 agataaagat gaaaattcaa acaaaaataa taaagataaa aatgaagaca aatctaattc
     9121 taaaagtaat aaagataagt catcagagga caaatcgtca gataataaaa atgaaattca
     9181 aaaaaataaa aaacttttaa tttgtataga cccagggcat caaggaaaag gagatagcaa
     9241 tttagaacca gtagctccag gttcttcctc taaaaaagcg agagtatctt caggaacaga
     9301 gggtattgct acaaaaaagc cagaatatgt tttaaactta gaagcatctc ttgttttaaa
     9361 gagtatatta gaatctaaag gttataatgt aataatgact agagagacac atgatgtaaa
     9421 tataagtaat tcagaaagag caatacttgc taatgacaaa aaagcagata tggttgtaag
     9481 aatacatgca gatagtttaa ataattcttc aaaaactgga gcatctatat tgattcctga
     9541 aaaagatgga aaatatacag ctcctatata tgaagaaagt aataaatgtg ctgaatttat
     9601 caaacagaat atggaacaat caggtataca aatcaatgga atcgttcaaa gaggtgattt
     9661 gactggattc aactggtcaa aagtaccagc tgtattagta gaaatgggat ttatgagtaa
     9721 ctataatgaa gaccaaatga tgtcaaatcc agactaccaa agaaaaatga tgcagtgtat
     9781 agctgatgga ttggatgcgt attttaaata agatatgaat agagaaaaag ttaggttggt
     9841 attattttcc taatttttat ctctattttt tattgtacat aacacaaaga agaagtttat
     9901 tttaggttaa attgtcgtaa atataactaa aaatattggg aatacttgat ttaagtttaa
     9961 aaagaatata ttatagtata gaatgtgtaa aatttttttg agaggtgttg aaatgctagt
    10021 agtagaaaat gtgagtcatg gatttggtgc gagaacaata ttagaaaatg tatcctttag
    10081 acttagaaaa ggtgaacata ttgcactagt tggtgctaat ggagaaggaa aatcgagttt
    10141 tttaaatata ataacaaaga agcttatgcc agatgctgga aatataaaat ggtcttcaag
    10201 agctacagta ggttacttag accaacatac ggtattaagc aagggaaaaa ctataagaga
    10261 agtgcttaga gaggctttta agcatatgtt tgacttagag caagaaatga ttgctatgta
    10321 tgacaaaatg ggagaagcta gtgatgatga aatgagtaag cttcttgaag aaacagcaga
    10381 gatacaaact atacttgaaa atagtggttt ttatatgata gatgcaaaga tacaagaagt
    10441 tgcaaatggt cttggtcttg gagaaattgg tcttgataaa gatgtaactg acttaagtgg
    10501 agggcaaaga acaaaagtac ttcttactaa acttctactt gaaaatccaa ctattcttat
    10561 attggatgag cctacaaact atttagacga agagcatata acatggctta ctaagtacct
    10621 tcaagagtat gagaatagtt ttgtcttagt ttctcatgat attgaattta taaataatac
    10681 atgtaatgta atatatcata tggaaaatgg agagttaaat agatataaag gaaattatga
    10741 tgaatttgta agacttaatg atataaagaa acgtcaagaa gaacaagctt atgataaaca
    10801 agttgaagaa agaaaaagac tagaggattt tgtagctaga aataaagcta gagtagcaac
    10861 tagaggaatg gctaacagta gacaaaagca acttgataag atggaaatat tagaaagacc
    10921 aaaagaaaaa ataaaaccta cttttgcttt taaagatgct agagcagcta gtaaaataat
    10981 ttttgaaaca gaaaatttag ttttagggta tgatgaagca ttgacaaaac cacttaattt
    11041 ccatttagaa agaggaaaaa agattgcctt aaaaggaatg aatggtattg gaaaatctac
    11101 tctattaaaa actttacttg gaataataaa accatttgaa ggaaatgtta aattaggtga
    11161 ctatttggaa gttggatatt ttgaacaaga gagttcaaga gaaaatagta atacacctat
    11221 ggatgaagtt tggagtgaat ttccagggct tacaaacttt gaagttagac aggctcttgc
    11281 aaaatgtgga cttacaaatg aacatataac gagtcaaatg agagtattaa gtggtggaga
    11341 agctgctaag gttagacttt gcaaagtaat gttaaaaaat ataaatttct tagtattaga
    11401 tgagcctaca aatcatttag atgttgaggc aaaagatgaa ttgaagaagg ctatcaaaga
    11461 gtttaaggga acagttcttt tagtatgtca tgagccagaa ttttattcag aaattgttga
    11521 tgatgtatgg aatatagaag attttacaac taaaatcgtg tagtgattta acttattgct
    11581 ggggggattt catgaaaaag tttctaaatg tacttttttc aatttgtatt agtattgtta
    11641 taatagtagg tgttattaat tttactgttg gatttaaaca actttattat tttgacattg
    11701 attacttaaa tatatcagag ttatctggtt tatctaaaga tgatataaaa ttgaactacg
    11761 attatctaat tgattataac ttaaataaga atgtgtctga gttcaaatta ccaacattaa
    11821 aatcttctcc acaagggaag atacattttg aagaagtcag gaatatattt caaaatataa
    11881 ataaattagc taaattatta ttggtagttt ctttagtagg aattatattg agtgtaaaaa
    11941 ataaaaatat aaaaatcttg aaaactacat caataacact tataattatg ccattattat
    12001 taacagttcc aattttatta aattttgaaa agtcatttat tatttttcat aaattattat
    12061 ttagaaatga ttattggata tttaatcccg atttagaccc agttataaat atattgccag
    12121 aggaattttt ttttcactct ggaatgatga ttttaatatt aattttgtta gtaagtatat
    12181 tactgtttgt aatgtataaa ttatgtaaat ctctatcaat aaaaatattt caatgttaaa
    12241 tagagggata tttttatttc caaaataaga taataaaaaa ggattagatt aaaagttata
    12301 caataaaaat agctgtgcaa taatatttag actatgaaag tagttgaaaa atatttatgc
    12361 acagctattt ataatagaat ttacttttta ctagtgattt taactaaatc ttgaaattta
    12421 ctcataatgt aattgtaatt atctttttta tgaggtaata tacaactact gcaatctttg
    12481 atacctttat ctgtatactt aaagtttcca ccacagtttt ctcctaaagc atacaaagga
    12541 caatagcaaa atagacagtt aaactcttct ggtttattag ttttatgaca agggaaaaat
    12601 tcgcaatctt tgtgattaaa aaacttataa ttttcgccca tattttcctc ctaattaaat
    12661 aaaatttaaa ttttttatac tatataagat tttggtgata atataattat actaaataat
    12721 tttatgaata gtcgataata tagtattatt aatcatagta ttaatggtat aattagtcaa
    12781 cagaaaaata atgtaaaaat aatgtaagtg tattttgtaa ttagaatatg ttttataaca
    12841 aaaaatgagg tgattaagtg aaagaaattc aagaaaaagc acttcttgta ggtctgaatt
    12901 tgactacaat agtgaaaaaa aatgatgata tagacactaa tgaatctatg gaagaattaa
    12961 aagaactaac aaaagctgct ggggcagaag ttgtaggtag cttaattcaa aataaacact
    13021 ctgtagatgc agcttattat ataggaaaag gtaaagtaga agaaataaga gcctatagtg
    13081 actctttaga tgctacttta gtaattttta atgatgaatt atctggtgct caaatcagaa
    13141 atatagagaa tgttgttgga agaaaagtaa tagatagaac tactttaatt ttagatatat
    13201 ttgctcaaag ggcacttagc aaagaaggta aattacaagt tgaattagca caattaaaat
    13261 atagattgcc acgactttat ggaatgggtg gtgagatgag tagaacaggt gcagggattg
    13321 gtactagagg tcctggagaa caaaaactag aaatagataa gagacatata cttaataaag
    13381 cagcagatat aagacgtgaa cttaaagaag taaaaaagaa tagagagaca cagagagtta
    13441 agcgtttaaa gtcaaatata ccgattgtag cacttgttgg gtatacaaat gcaggaaaat
    13501 ctaccctgtt gaacgaatta ataaagacac acaaggatta tgaacaagaa aaagaagttt
    13561 ttgtaaaaga tatgcttttt gcaactttag atgtaacttt gagaaaggct cttttgccaa
    13621 ataaaaaaga atttttagta gtagatactg ttggatttgt aagtaaactt ccccatgatt
    13681 tagtagaagc gtttaaggca acattggaag aagtacagta tgcagattta atcttacatg
    13741 taattgatgc aacaaatact agttatgaat tgcaaaaaag tacgactgaa ggtgtattaa
    13801 aagaacttgg tgtaaatgat aaaaaacata tacttgtata taataaagtg gacaagctag
    13861 aattggatat ataccctaaa agtcaagaag atattgtgta tatttctgca aaacaaggca
    13921 taaatatgga taagttatta aatatgatag aaattgcttt aatggaaaat acttattcag
    13981 taagtttgat gttaccttat gagagaggtg atatatttag tagaataaaa gataaatata
    14041 atgtggagaa ttttgagtat ggggaaagtg gtataacgct agatgtagat ttagatgaag
    14101 aagattttaa tatctataga gagtacatac tagaaaaata ggttgaatat ggatataaac
    14161 tgggaaaata tagataatct tgaagattat tttataacct atcttcttta taaagaatct
    14221 aaaacagtat ctcaaattag taaaattaga aatatttcaa gtactgaagc aagtgagcaa
    14281 cttatacaag caaagttaaa aataaaggaa atgcaaaaag atgattttga ggcatctaag
    14341 gatattttgg ataaatttct agaactagat aaaattaaga gacttgattt tatggatagc
    14401 ttagatgacg aaaaaatggt atactttaag agaaaggttt tcaaaagaat ccttgtagaa
    14461 aaaaatgctg aagatttaat tgttttaatt tgggcgacag gtgagctaaa agatgatagg
    14521 tttttgaaat tgcttcatca gctcacaaac cacagacact cagatattag aagaataact
    14581 tattcagcaa tcagaaagat tgaatcacca agtagtagag aagtactgca aaaaggtctc
    14641 tacgacaaaa atgcacagac taggcagtac tgtgcaaaag ctctttcaaa attgggagat
    14701 gaaaacagtt taaagatttt acagcagttg aaagacaaga ataagaattt tgaaaaagaa
    14761 tatgtgctta gagcttatga cgaagccatt aagtcattgg aaaatgcaaa aaatttgaaa
    14821 aagtaatttt ttattaaagc aatttgttta cttaatgatg tatttctaaa gtttaacaag
    14881 gtaataaata aattaatggg aggggtttca aatgatagta agacgttgtg caggtggagt
    14941 agtgttttat gctaataaag tacttattgt aaaaaatgat aggggtgaat ggacacttcc
    15001 aaaaggaaag atactaggag ggggacttcc atatgagagt gctgttcaaa gagttaaagt
    15061 agaaactggc atagatgcta aaatgataga tgtggctggc gatactatgt atgaattttt
    15121 ctcaagaagt agacaacaag aagtttgtaa tgcaataatg tggtatgtta tggaagcttg
    15181 taacactgat tgtgtacttg ctcctgaatt tcaagaaggt ggattttata aagtaaagga
    15241 tgctttagaa atgttatcac atcataaaga gcaagcttta gtagaagtat cttataaaaa
    15301 gtttaaggaa ttaaagaaat tagtttcaga gggcgatgat gttccagcaa attaattgtg
    15361 aatttagagg attctgagga agggatagcc ccttcctttt ttaattgaag cagttttaag
    15421 cgtaaattat atagtctctt taaactatga tttatcaatt tagagattta gtagtttata
    15481 tttaaaatca gtaagatata tttaaaataa aaattaaaaa gtatacaatt ttattatata
    15541 attgtcttat gatgttgatt aaagaattat taaaagtcca tttattttta aatagaataa
    15601 ttttataaat atatatttga tgtgtatatt agaaaatgat taaaatagga ggaaatacaa
    15661 tgagcaatta caggacatta catgaatttg gaacggatga aataacgatt gaaaagtctg
    15721 tttttattgg atatgctaag cctataaaga gtgaagaaga agcattagag tttataaatg
    15781 aaataaagaa aaagcataaa gatgcaactc acaatgtgtg ggcttatact gtaggtaaaa
    15841 atatgaatat acaaagatat agtgatgatg gagaaccaca aggaacagct gggataccta
    15901 cattagaggt tataaaaaaa gaagatttga gagatgtagt ggttgttgtt actaggtatt
    15961 ttggaggaac aaaattaggt gcaggtggtc tagttagagc ttatacaaaa ggtgctaaac
    16021 tgggacttga agcaggtaag ataatttata aggtaatgta tcaagaagtt aaggttaaga
    16081 tagattatac tcaacttgga aaagtgcaaa atgagttaat gaatttgggg tattttataa
    16141 aagatactgt atatgaggat aatgttgaaa tagtagtata ttcaagatta gaagatgtag
    16201 agaaattatc agaaaaaatg attgatataa caagtggaac aggaaaaata gttttaggag
    16261 aggaatttta tttgtctgaa caaaatggag aaattttaat ataatctaaa aggttattag
    16321 aatagttaat acctcaaata gccaattagt atttttaagt gaaaagccat taaattgatt
    16381 taatctaaat caatttaatg gctttttatc ggattttgca cagaatcctt tttttacttc
    16441 aaataaaccg actaaaagta aaaatattcc aaatattttt tttaatatat ctgaagacag
    16501 ataattagct aatagtgaac caaatacagc tcctaaaacc ccaaacacag ctataggtat
    16561 aaccaattta aaaattacat ttttattttt tatatgtata gcaagtgcta taagtgtcat
    16621 agggatagat gaaagtaaat ttacgctttg tgctatttta gtgtctatgc cagcaagtaa
    16681 aacgagtgca ggtataagga ttgttcctcc acccattccc attcctccaa taattcctgc
    16741 aaaaaatcca attagagcaa ataacattaa aacaccatcc ttaatgctgc aattatcata
    16801 attattccaa aagaaattct aagaaatttt ccagtaacct tatttagtaa tttagctcct
    16861 ataataccac caagaatact tccaactgca actttaattg ttaagttaac atcataagta
    16921 cctttagata catataaaac agaacttgct gtcgttaaga atattattat agaaagagca
    16981 gttgcatgag atttatgttc ttctacctta acgatgtcat ttaatattgg aactaaaaga
    17041 gtacctcctc cagaaccaaa aactccattt ataaatcctg taaaaactcc aattatcgta
    17101 ttttttaagt taaaatcaaa gtattttttc tttaaatcat cagttttttt cataaaaatc
    17161 accttctgaa atagttttac caaaataggc aaattatatt tatataaaat aagattaaat
    17221 ataatctttc atgtttgttt aattttgcat aaaaaaaaac atattaaaac aacatattaa
    17281 tatatggtat aatatattaa aacaaagtag caaatttgag aggagataac aatgtcaaat
    17341 ataaaaatac aaatagacaa aactgtagaa tggcttataa ataaggttaa tgaggcaaat
    17401 gcaaaaggat taattgttgg tgtatctgga ggaattgatt cggcagtagt tgctaattta
    17461 attaaaaagg catttccaga aaactctatg ggagttataa tgagcataaa aagtaatcct
    17521 caagatagag aagatgcact taaggttata gagggatgtg atatagaata ccttgattta
    17581 gaccttatag aaccacaaag tgctatatta gacatggtag taggaaattt aaaagataaa
    17641 catttatata gagaagaata tttaaagatg acagatgcaa acttaagagc aagagtaaga
    17701 atgagtacaa tttatacaat tgctaacaat ctaggatatc tggttgttgg tacagacaat
    17761 gctgcagaaa tacacacagg atattttact aaatttggtg atggtggagt tgatatttta
    17821 cctattgcaa atttaactaa aggagaggtg tatgaatggg caaaagagct tggtgttcat
    17881 gaagatttaa taaacaaagc tccttcagca ggtctttggg aaggtcaaac agatgaagat
    17941 gaaatgggaa ctacttacaa tatgatagat gctgtgttag aaggtagatt ggatgaagtt
    18001 cctaaaagag accaagagat aattgaaaga cttcatagat taagtgaaca caagagaaaa
    18061 acgcctgcac aacctcctaa gttctaattt actatttata agatttgtga taaaatttac
    18121 aagtgatgaa aattagaata attaattgta cgtattaagg agtggaaata tgggacgtat
    18181 aggtaatata attaatagaa aaggtaaaca agatgctcaa agagcaaaga tatttactaa
    18241 acatgctaga gcaatagcag ttgcagctaa agaaggtgga gcagacccag agtacaatgc
    18301 agcgttaaaa acagctatag aaaaagctaa ggcagataat atgccaaatg ataatataga
    18361 tagagctatc gctaaaggtg ctggagcagg tgctggagaa gactatgaaa ctatagttta
    18421 tgaaggatat ggacctggtg gagttgctgt tatagtagaa actttaactg acaacaaaaa
    18481 cagaactgct ggtaacgtaa gatactattt tgacaaaaac ggaggaaact taggaactag
    18541 tggatgtgtg tcttttatgt ttgataaaaa aggacaaata ttagttggtt taggagatgg
    18601 agtttcagaa gaagaattga tggatgttgc attagaagca ggagctgaag atttcataac
    18661 agaagaagat ggttatgaaa taataactac accagaagat ttttctagtg ttcgtgatga
    18721 gttaaaagct aaaggatatg agtttatatc tgctgatgtg aagatgatac ctcaaactac
    18781 aactgtattg actgaagaat ctcatttaaa aatgatgaat aaattagttg atatgcttga
    18841 agaagatgat gatgttcaag atatatatca taactgggaa gtagaataaa tagtataagc
    18901 atattgaaat ttataagtat tgaatcaatt ttaacatgtg ataaatttta tagaataaga
    18961 aacactaaaa tagacatacg cacctctaac ctatatttgc ataataatat gtaagcatag
    19021 gtaaggggtg tttttatatt tataggttaa gaaatttaaa gtaaattttg agctggactc
    19081 gattgtctat aaataattga tgggtatata acttgttgct gaataccatt tatacgccca
    19141 gttactgtat caataatcat cctaagacta cgttctgctg tctcttccat ttttaaatct
    19201 ataactgtca aaggaggaat acttcttgcc attagtcgtg aaggtccatt acttgctgca
    19261 aatatttgaa tatcctctcc aattacaatt cccgattcat gaaatgcatt catcatacca
    19321 agagctacca catcatgatt acaaaaaatt acttttttta gtgaattttt tgcaagcatt
    19381 ttttgagcaa tatcatatcc actatctatt ttattagaac aataatatat agaatctgat
    19441 agatgtattc catgttcttt acatgttttt aaaaaagatt taccccttaa agtcatacat
    19501 gtaaaggaag ttgggttgaa tacaacagca atatcatttt taccattttg aatagcatgt
    19561 aaagctgcta tacgaccagt ttcctcatta tcaatagata cacttgaaaa accaggtatt
    19621 tcacgattta caacaactac aggaatttta ggtttatttt ttactagata ttctatatca
    19681 tcagcattga tacctgttaa aacaattcca tcataataat tatttgcaaa aaagtattca
    19741 tcatcacata gatgaccaac tttgtaaggt cgtatgatga tatttatgtt taaatgttct
    19801 aaagaaatta tgtggtttat tgcttgaagt atattggttg atgccaactc aaatccctca
    19861 tcctgccaat aaaaagctat tttaatatta ttatgtttaa taggagtaga gcgtttatat
    19921 ccaagcttat cagctgaatt taatataagc tcttgtgtat gtagcggaat cctgcgttca
    19981 tttcctttac cacttaagac gtacgagaca gttgctgaag aaagaccaca gtcttttgca
    20041 atatctttga ttgttgccat gataaaatcc tccttaaata gttgcttaaa tttgcttata
    20101 ccaataatct taacatatat tcaactaaag aacaatattc tacaaggtgc atattttaca
    20161 ggattagaat aaataaattt aaaaaaactt cttacttatg ttgacataat ttagtttata
    20221 ggattataat atgcttaaat aagcttatta ttaacttaaa ttaagcaaag ttaagcagga
    20281 acatgcaatg ctagcttgca atgtgactgt aaagggggaa aaggtatgag taaggtaaat
    20341 atatttgaag ttggtcctag agatggattt caaaacctga aagagttttt agaaactgat
    20401 aaaaagctta agattattga tggtcttatt gcttcaggga ttaaacaact tgaaattagt
    20461 tcatttgtaa gcccaaaagc aatacctcag atgaaagatg caaaagaagt agcaacttat
    20521 tgtgtagaaa aatatcctga tgtgaaactt tatgcattag ttccaaattt atacggtgct
    20581 aaagttgcat gggagtgtgg tataagagat atatcctatg ttatatcttt gagtgaaact
    20641 cataataaaa aaaatataaa tcgtacccat gaagagtcta ttgatgagct taaaaaaata
    20701 atgaatactt atccagacat gaatatatgt attggaatgg ctactgtatt tggatgtcct
    20761 tttgaaggtt taccaaaaat tgaagatgcc ataagatttg ctaaacgcct ttgggaaaac
    20821 ggtatcaggg agatgaatct agcagataca atagggattg ctgaccctaa gcaagtaaga
    20881 gaaactatta gtgcattagt tgaagcttta ccagagtgca gatggcaggt acatattcat
    20941 gatactagaa atatgggaat ggttaatact cttgtggcta ttgaatctgg aattactact
    21001 gttcagtcta cacttggagg attaggagga tgcccatttg ctcctggagc atctggcaat
    21061 actgcaactg aagatttagt atatatgctt gaacgtatgg ggtatgatac aggagttgat
    21121 tttgttaaac ttcttgaatt atcaaagtat cagaagagtt ttgtaaatgg agtatatagt
    21181 ggtcatcatg taaatataaa gtctgatagt tgtaattgtt agttctattg attaatcgat
    21241 taaaaaaata tgttgattaa aaaaatatgc tgattggtaa aatagattta ttgataaaaa
    21301 atataaatta taaaatacat tatctaataa aacaaataaa aaaattgagg gggattagta
    21361 tggatattat agctttactt ttatttttag gagttattat tattgcattt gtacgtaaga
    21421 ataatgcagg tattttggct ctagctattg gtgtcatagc tgttagaatt tttggaatgg
    21481 atgataaaga actttatgga gctataagca actcaatgtt tactacactt gttggtataa
    21541 cactactctt tgcaatagtg aactcaacag gagcattaaa gcttgttgca gaaaaaattg
    21601 tagctgcttc tggtaaacgt gtttggctta tacctatagc agtttttata gcaggatttg
    21661 ttgttgctgg tgttggacct ggggcaattc cagcacttgc aattatccca gcaatggctg
    21721 ttcctgtagc cataacagtt ggttataatc ctgtaatgct tgcacttata ggtgaatgtg
    21781 gattaatggc aggtcgtatg actcctatta ctccagaagg tcaaattata acaaccgttg
    21841 cagaaggggt tggaattgaa aatgttatgc ctactatctt agcctgtcaa actctttcta
    21901 caattgtatt ttcaatagta ttgtttataa ttttcaaagg atataaactt aaaaaaccta
    21961 taaatgttat agatagtaag caaatagaaa aattcaatat aaagcagata atttctctaa
    22021 taagcatagt agttatgatt gcttttatca taatttttga tatgaatgtt gggcttgcag
    22081 cttttgcagt ttcagctgta cttatttttt tcaatattgc tgatgaagga gaatgtatca
    22141 aatcaattcc atggagcacg atagtaatgg ttcttggagt aggtgcaatg atgacaatcg
    22201 tagatgcagc aggaggtatt gacttgatga gtaatgcatt atcatcactg atgaatagta
    22261 aaacagctac tccaattatg agtatttcag caggacttat gtctatggtt agttctgctt
    22321 tagcagtagt ttatccaact atgatgccta tgtgtgttga tatagctaag gcagttggag
    22381 gagtagaccc actagcactt attgctgcag ttggtgttgg aggttctctt gctggtgtaa
    22441 gcccactttc tactggtggg gcattgattt tagcagctat gggttcaagt aagaaagact
    22501 ttaataagga agaacaaaat aaggtttttg tacagctttt cattatgagt gcagttggct
    22561 tattggttat tgcagtagta tcaatattat catttaatgc aataacacat ttaatgaact
    22621 aattagaata actgaaaata aatcattaaa tttaactttt aatattaatc aatataatat
    22681 aatttggagg ggaagttatg aaaaaaggag cattaagcaa tataaaggta cttgacctta
    22741 caagagttct tgcaggtcca tattgtacaa tgatgttggc ggattttgga gctgatgtta
    22801 taaaaataga gatgccaaga aaaggtgatg atacaagagg ttttggacct tttgtaaatg
    22861 gagagagttt atactatgca aatataaata gaaataaaaa aggtatcact ctaaacctta
    22921 aatcagaaga aggaaaaaat atatttttag aaatggtaaa acatgctgat gttgtagtag
    22981 aaaattacag accaggtgta atggaaaagt taggtctggg ttatgatgag ttggctaaag
    23041 ttaacaatca aataatttat ggagctgtat caggatttgg atgttatgga ccatattcag
    23101 aacgtccagg ttatgatatt attgcacagg caatgggtgg tcttatgagt ataacagggc
    23161 aagaaggagg agaaccaacg agagttggta atgctatggg tgatgtacta ggtggaatga
    23221 atttaactat tggtatactc acagcactca acgctagaaa aataatagga aaaggacaaa
    23281 gagtagatgt ttccctcgtt gattctgttg tatcgtctct cgaaactggt atacagagat
    23341 actttgattc aggacaacct gaacttatgg gtaatagata tgcttcagcc tatccttatg
    23401 actcttttaa ggcaagtgat ggaagttttg taataggctg tggtaatgac aaactttttg
    23461 aaaagttatg taaaaaagtt ctttttagag aagacctttt aatagatgag agatttaaaa
    23521 caaatcttaa tcgttgtgaa cattacaagg ctcttaaacc agaaatagaa aaatggtctg
    23581 ttaagcatac aataaaagaa gcagttgact taatatcaga ggctggagtt cctgctgctc
    23641 ctatctataa tcttgattgt gttacaacag atgaacatat agcaaaagca agagaaatga
    23701 ttgtagatat tagtcatcct attataggaa atatgaaagt caatggaaat ccagttaagt
    23761 tgatgacaac aaaagctaaa attgatatgc cagcaccatc tctaggggaa agtaacgagg
    23821 agatttataa tggttggctt ggttttgata gtgataaaat aaaagattta aaagaaaatg
    23881 gagttatttg attaaaaaat agctaaacac acttgtgact ttagtcatgg gaggttcagt
    23941 tagaataata tcaaaaaata ttaaatcaat actgtaaata aaatatagaa ttgtcagaag
    24001 catttaagat gggaaaagct acttagacat tgagtctttg tggcttttcc tattttcatt
    24061 aagaatttta tattatcaga atagatatgt actaaactaa agtattaaca atttaaatta
    24121 atagaaaata aactacctaa ttatgttgaa taaagactac tttagtgaaa ataaacttat
    24181 agagatgcta tttaaattat tttaatggaa atatcaaaaa tgagactgca ttctcaaaaa
    24241 tgagactgcg ttttttaagt attttctcga aaatgagaca aaaatattgt tttatgggtt
    24301 ttattgaaga aaaattcttc tgtgaattac aatttaatca attttaaagt tgaaaattat
    24361 taaaaattta gtgaaattta tgtatatttc gtttatttta ttaaaaataa caatttttta
    24421 ctaaaaataa agaacttcaa tggtgattgg catagtactt gctattttat attaacaaga
    24481 aatgtagaaa aaataacaat gtataatggg gggaatatga tggaatctgt aatggaaaat
    24541 ttgaacaatc ttaaggtgga gcttaaggac aaagtctgtg ttattactat aaatagacct
    24601 aaagctttaa atgctcttaa tagtgacact cttagggaac tatcacaagt tattgatgta
    24661 gtatcagaaa atgaggcaat attaggagtt attattactg gagaaggtaa agtttttgta
    24721 gccggtgctg atatacgcca gatgcaaaac tataaaagtg aggaaggcag aaaatatgca
    24781 ggttatgctc agggaatttt tgataaaatt gaagctcttg agaaaacagt aatagcagca
    24841 gttaatggat atgcattagg tggtggatgt gaacttgcta tgagttgtga tattagaatt
    24901 gcatcagaaa aggctatatt tggacaacct gaagttaatt taggagttat tccatgtttt
    24961 ggtggaactc aaagattatc aagacttgtt ggaactggaa tagctaaaga gttaattttt
    25021 acagggagac aagtaaatgc agaagaagct aaatctattg ggcttattaa taaagtggtt
    25081 ccaagtgatt tacttttaga agagtctatg aagatgatga accaaatagt tgaaaaagcg
    25141 ccaatagcaa taagatatgc aaaagttgtt attaacaaag ggatagatat ggatttaaag
    25201 aatgctcttg aactagagaa agatattgca ggtttaactt ttgctacaag agataagcaa
    25261 gaaggaatga atgcatttat agaaaagaga aagccagttt ttgaaaataa gtagctatta
    25321 taactaaaat tggaacaatg tagaatatat tcaaaatcta aatttcgtga aaaaatacat
    25381 atagtttaat tttaaaagga gttaatttat gaatacggga gtaattataa gtttagtagg
    25441 gattatcata gctctatctc ttctagttgt aatggttatg aagggaataa atatttttat
    25501 tatagcaatt gtatgttcat cattagttgc tataacagga agcctaaatg tgtatgatgc
    25561 acttaaagtg gattatatga cagggtttgt tggatttctt caggcaaatt tctttatttt
    25621 cctaacaggg acattaatgg gaaaaataat ggagattact ggtggagcaa aatctattgc
    25681 taagatgatt gtaagatgga ttgggaagga taaagcacta ctttctattc caatagcttg
    25741 tggaatatta gcctatggtg gagtaagtgt tttcgttgta agttttgcag tgtttccgat
    25801 agctttagaa atttttaaag aagctgattt gccacgaaga tttataccag cagctttgac
    25861 ttttggatgc tcaacttttg ctatggttgc accaggggca ccacaaattc agaatattgt
    25921 tccagcatca acattaggga cagatattat ggctggagca gtaaatggtt ttatatcatg
    25981 tgcagtaatg tttatagttg gaagtacaat tttgtacaaa atggtttcaa aagaaaaagc
    26041 caatggtggt cattttatag cacatgaatc agatatattt gatgaagcag aagcaactaa
    26101 ttctaagaga gaaaatggtc ccaatggtgt aattgcctta attccattga tagtgtcaat
    26161 tttaataatt aatgtaaaag ttaatggaaa agcgatagta ccaattgagg tgggagtatt
    26221 tattggagct ttattagtat atttattgtt aaataaatat caagataata ctaaaatagt
    26281 tggacatgtt ggtgatgcat gtaaaactac agtagtagca atatgtaata cttgtgctgt
    26341 agttgcattt ggttcagtag taaaatcagc agttggtttt gacttcatag ttaatgccat
    26401 gactaatatt cctggtcctc ctattgcagg ggctgcagtt ggaactacag ttattgcagg
    26461 tatttgtggg tcagcttcag gtggactagg aattgcagct ccacttcttg gaccagtatt
    26521 tttagccaag ggtgtttccg ctgcagcatt aactaggact atggcaattt catcagcagc
    26581 attagattca cttccacaca atggatatat tgttactgta acaaatggtc tttgtaaaga
    26641 aacacataag gatgcctata tgccaatatt ctgggtaact gttttaaccc catttattgg
    26701 aaccatagta gcagtcctac tgtttacaat gttcccggga ttgccataag agaaaagata
    26761 aaaggtataa attatatttt gatgttataa aatcaatttt caaaatatat acaataaatt
    26821 tcatgtttta atactgtaaa tatgtattta aaataacaaa ttgaccatat aaggaggaat
    26881 tgaaagtgtt aaataaacca ttagagggag ttaaggttat tgacctaacg tattttgtag
    26941 caggtccagg gacttctaaa atattagctg actggggtgc tgacgttatt aaggtagagc
    27001 caagctttgg agacccagga agaaagacag gggcaacaat gacaatgcca atagatgatt
    27061 ataataatcc tttttacagc acatataatt caaataaaag aggtttgtct ataaatctta
    27121 agagtgaaac tggaattgaa attatggata agcttttaag cgaagcaaac gtatttgttt
    27181 caagttatag aacaggagcg ttaaaaagac taggtcttga ttatgaatca ttaagtaaaa
    27241 agcatccaca ccttatctgg ggtcagataa atggttttgg cgattttgga cctgctaagg
    27301 ataatgcagg atttgataca gttgcctttt gggcaagaag tggggctatg cttgatatag
    27361 cagaaaaaga tacaagtcca ataaatccac ctatagcctt tggagatgca acaacttctt
    27421 gtagtttatc tggaggaata tgtgcagctt tgtaccagca agctaagact ggcaaaggac
    27481 aaaaagtaat ggcatcttta tttgggcaag caatatggaa tgcatcatct ttattagcat
    27541 ctacacagtt tagtgatgag tatccaaaaa ctagaaaaaa tgctatttca ccagtaataa
    27601 attcttatcg ttgtaaggat ggaaagtgga tattcttaag tattttagag catgaaagat
    27661 attttgaggc actttgtaga ttatttggaa gagaagactt aataaaagaa gagaaatttg
    27721 catcttcagt agaaagtaag aaaaatgcta cagaacttat taatattttg gatggtgaat
    27781 ttgcaaagtt tactcaaaat gagatggttg aaaaacttac tgctgctgat atagctcatg
    27841 aaaaaattca acatgttaat gatgtagtga ctgatgaaca ggctattgct aataactata
    27901 tatatgaaca tacaagtaaa aatggaaata agacaatgct tgcatctact ccagttaaat
    27961 ttggaaatat tgaagttaac atgacttgtg atgctccact tataggagaa cattcagatg
    28021 agatattgag agaacttgga tacagtgatt ctgatataga ggctctaatt gaatctggaa
    28081 ttgtaacaat gaataaagaa gcatgtgaaa tatgttaata aacatgtgaa gtatgttaat
    28141 aaataggagg gaattttatg gattttagat taacagaagc acaattaatg cttcaaagag
    28201 tagcaaaaga atttgcagag aatgaaatag caccaatagc tgctgaaaca gataaaacag
    28261 gtatttttcc aagggagctt tttagcaaaa tggctaaaat aggatttaat ggcattggaa
    28321 cacctgtaga gtatagtggt tctggtgggg cagatataga aaaggtaatt gttgttactg
    28381 agattgccaa aaaatgtgca gcatctgcag caatattatc aatacacaca atatatgctc
    28441 aagctatttt gaaatttggt actgaggaac aaaagaaaaa ataccttcca atgatggctg
    28501 aaggtgggtg tgtaggtgct tttgccttaa ccgaacctaa tgctggttca gatgctgcaa
    28561 gagctgcaac aactgcaatt attgatgaag aaactgatga atatgtttta aatggaacta
    28621 agtgttttat ttctggtgga ggtcaagcag aatcattaat aatatttgca cttacagacc
    28681 catcaaaggg aataaaggga atgtctgcta tcattgtcga caaaggtact ccaggttttt
    28741 caataggaaa aattgaagaa aaaatgggta ttcatggttc agaaactgca gagttaatat
    28801 ttgataactg tagagttcca aagtctaact tattaggaaa agaaggcaaa ggatttaata
    28861 tagctatgac ttgtttagat ggagcaagaa ttggagttgg agctcaagct gtaggaattg
    28921 ctgaaggggc tttagaagaa agtatcaaat attctaaaga aagagtccag tttggcaagc
    28981 caatttcagc tttgcaaggt attcaatggt atatagcaga tatggcgaca atggtggaat
    29041 cagcaaaatt attagtatat tatgctgcag atttgaaagc tagaggagaa aaacacacta
    29101 aagaagctgc tatggcaaaa tacaatgcgt cacgtactgc aagagaggtt acaaatttag
    29161 cccttcaaat ccatggtgga tatggatata tgaaggatta tccattagag agaatgtaca
    29221 gagatgccaa aataacagaa atttacgaag gtacttcaga aatacacaaa gttgttattt
    29281 caagagcagt actaggatag gaggaaaaga atgaatatag ttgtttgctt aaagcaagtt
    29341 ccagatacta atgaagttaa aataaataaa gagacaggta ctctaataag agatggtgta
    29401 ccaagtataa tcaatccaga tgatagaaat gctttagaag aagctctaaa aatgaaagat
    29461 gaactaggag cagtgattaa ggttataagc atgggacctc ctcaagctaa aagtgcttta
    29521 aaagaagctt tggcaatggg agctgatgaa gcttatttaa tctcagatag agcttttggt
    29581 ggttcagata cttgggctac atctacaatt attgctgctg ctatagagaa ggttggaaag
    29641 tatgatgtaa tattctgcgg aagacaagct atagatggag atacagctca ggttggacca
    29701 gaggttgcag aatttttagg gataccacaa gttacttatg cgaaagaagt aaaggttcaa
    29761 gatgacaaat tactagtaac tcgttataca gagacagggg attatttaat agaagcaaag
    29821 atgccagttt tattaactgc tataaaagag ttaaacaatc caagatatcc aagtgtcaaa
    29881 ggaatcttag aagcttataa taatggagat gcaaagatta ctgtattaac acttgcagat
    29941 ttagatgttg atacaactca aattggatta aagggttcac ctacaaacgt ttataagtct
    30001 tttgtaccag ttaaagacaa gcataatgaa ataatagaag gtataaataa aaaagaaaaa
    30061 gctgagaaac taatagaaat actattcgat ttgaaactag tataggagtg ttaagatgat
    30121 gagagcaaaa gttaatcaag gtataaattt aaatgattat aatggtgttt gggtaatagg
    30181 agagcaaagg gaaggtaaaa ttaatcctgt tacgatagaa cttattggtg aaggaagaaa
    30241 gcttgctgac caattaggaa aagagcttgc agttgtgata gctggatatg aagtagagaa
    30301 agaagtgaag gaattacttc actatagtgt tgataaagta tattacatca atgaccctct
    30361 tcttaaagat ttcactactg atggatatgc aatttcaatt gcaaatttaa tcgaaagaaa
    30421 aaagccagag gttgtattgg ttggtgctac ttctatagga agagatatag cgcctagaat
    30481 tgcaggtaag gttggaacag gtctaactgc tgactgtaca aaacttgaaa tagattcaac
    30541 agataataag ttattacaaa caagaccagc atttggtgga aatttaatgg ctactattgt
    30601 ttgtccaaaa aatagaccac agatgtcaac agttcgtcca ggagttatgg caaaagctgt
    30661 aagaaacgaa tcagagactg gaattttaga agttgttact ccagaactta ctgaaaaaat
    30721 gattagaact agattagtag agatacttcc acaagaaaag aaatctgtaa atctaactga
    30781 tgctagaata atagtatcag ggggaagagg attaaaaaga gcagaaggat ttgagcttat
    30841 aaaagaattg gctgataaat tgggggcaga gattggtgct tcaagagcag cagtagattc
    30901 agggtggata gaacattctc atcaagtggg acaaacagga actactgtta gaccagaact
    30961 atacattgca tgtggaatat ctggagcaat acaacattta gcaggtatga gtgattctaa
    31021 atatatagtt gctataaata aagatgcaaa agcccctatt tttagtatat gtgactatgg
    31081 aatagtagga gatttatatg aaattatacc tgaaatgata gaatcattaa ataggtaact
    31141 tttagaaaac attgaatatg tagaatgata agtcttataa tattgtattg taagacttat
    31201 tatttttgct gaaggttata gtggggagat gaaacaatga aagagcagtg gtataaggat
    31261 atatttgcaa gagtattatc tatgactgat gatggtttta ttgttgtaaa tacaagtgga
    31321 gtaataatag atattaatga taaatattgt gactttttag gaaaagaaag aaaagatata
    31381 ataggacaaa atatacaaag tattatacca aatacaaaaa tgctagatgt tatgaaaaat
    31441 aagtattgtg aagaaggagc tatacatcat tattcaggtg gaaatacaaa agaaaaaagt
    31501 gtaatagtaa gtaggtctta tgtggaaaat gacaatggag aagtagttgc aggagtagct
    31561 caagttaaat ttagattgca atcatttgat gtagctaaaa agctaatgtc agaatatatg
    31621 gagctccaat attataaaga gcagtttaag gataactgtg gttttgacaa gctcataggt
    31681 gaaaatagag acttcataga acttaagaaa acaggtgtga aagcttctaa aacaaacttt
    31741 ccagtacttt taacgggtga aacaggtaca ggaaaagaag tctttgctag agcaattcac
    31801 aataatagca gcaggtcaga taaacctatg gttagtataa actgcgctgc aataccagaa
    31861 gaattattag agtcagagct atttggttat gacgaaggag cttttacagg agcaaaaaag
    31921 ggtggtaaaa aaggtaagtt tttagttgca aataatggta caatcttttt agacgagata
    31981 ggtgacatgc ctttgaccat gcaagcaaaa cttttaagag ttcttcagga aagtgagata
    32041 gaaccagtgg gaggtcttaa aactataaag atagatgtaa gagtaatctc tgccacaaga
    32101 aagaatttaa gtaaaatggt tgaagaggga ttatttagag aagacctata ctatagatta
    32161 aatgtaataa acattcatat gatggaattg aaggacaggc aagatgatat tttattgcta
    32221 gcaaattata tattaaacaa attaaatgtt gaatacaagg aattgaaggt tttaagtgat
    32281 aaggttaaaa attgttttat taactatact tggccgggaa atataagaga actacaaaat
    32341 gtaataaaaa gtgcctatgc tgtaagtgat gatatggtca ttatgatgtg tgaccttcca
    32401 tctaagatgg ataatatcag cagagtagct caatgtaatg tggatagcaa ttgttcaatt
    32461 catgaaatgg ttgagaatta tgaaaagagc ttaattattg atgtgttaag gaagtataat
    32521 tggaaatgtt ctaaggcagc agaggttatg ggaatacaca agagtctttt atataagaaa
    32581 ataaaaaagt atgaaattga attaaataat taagataaat tgaattaagg caatgctaaa
    32641 aaaacgccct tattcaaagc gaactgtata aactgtttta tgcagttaaa acgtgtaaac
    32701 gtagatgtga agtactaatg tcaatcatta gtactttttt attatattta taattactat
    32761 ctatatttca gtatcttttg atatctaaga ttattatgtt taatttagga tataacaaaa
    32821 ccctcttagt tatggacagt tttttatatt ttaactgtct actaagaggg gatagtttag
    32881 tttaaattta gagtaaattt tatctagcat ttataaaaaa tattttgaat agcttttttg
    32941 ttatttaatc ataattttct acttctttat caagttcttt gccacaagaa tcacacttat
    33001 atatagcatt gtatccgtaa tcatattcat caactatttt cttttgtcta aatacaccac
    33061 cacactcaca taggaaacca atttttataa gtgtaacgat aaattgtgat tttataaatt
    33121 ttatatcatt acatttatcg ttagtgtaaa atgtataaat ataagagtta tcgcactcat
    33181 ctcttaattc aaatctttca atatatgtgt tattttttaa ttcctcaaat tcttctttag
    33241 ttaaatatga tttttgttgc aattcatgta aacgcttaat ttggtccatt atttatatcc
    33301 tcccaataat tttagtattt taagcttaga taaggaatct aagttttatt aaatttatcc
    33361 caaggaatta tttaaatcat atttagtttt attaattaca acatatataa attacacgaa
    33421 aataaaacta attgtaaaaa taatatcctg tgaaaaccta aactactaac cccttactaa
    33481 cccgaaaact aaaaaaagaa aatatatcca aatataagtg atatataaat aaagatgttt
    33541 catataaatt
//
LOCUS       DAEQAF010000039        33220 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.040, whole genome shotgun sequence.
ACCESSION   DAEQAF010000039 DAEQAF010000000
VERSION     DAEQAF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33220
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.040"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            230..547
                     /gene="flgB"
                     /locus_tag="KRN00_001899"
     CDS             230..547
                     /gene="flgB"
                     /locus_tag="KRN00_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBH1827765.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYITFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMATLQYNALISFANGKIAMTKSII
                     SGR"
     gene            555..959
                     /gene="flgC"
                     /locus_tag="KRN00_001900"
     CDS             555..959
                     /gene="flgC"
                     /locus_tag="KRN00_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBH1827766.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKEVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            969..1286
                     /gene="fliE"
                     /locus_tag="KRN00_001901"
     CDS             969..1286
                     /gene="fliE"
                     /locus_tag="KRN00_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBH1827767.1"
                     /translation="MPITQINNLMQGAKLDNLIGEAKPLTLNNKEEKKNFEDVIIDTI
                     DKVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNK
                     VQI"
     gene            1311..2861
                     /gene="fliF"
                     /locus_tag="KRN00_001902"
     CDS             1311..2861
                     /gene="fliF"
                     /locus_tag="KRN00_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBH1827768.1"
                     /translation="MITSFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDAQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTGGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVDENNQPINSGISVDKNKASEQALNKQLEKSILEMLEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSAANNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVIAVGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            2874..3944
                     /gene="fliG"
                     /locus_tag="KRN00_001903"
     CDS             2874..3944
                     /gene="fliG"
                     /locus_tag="KRN00_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBH1827769.1"
                     /translation="MSTEITNVNAFDLSDINESDKNEKVEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNVKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSISGDDFNDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQNPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAADALKEEMEMVGVIKVTQVEASQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            3937..4668
                     /locus_tag="KRN00_001904"
     CDS             3937..4668
                     /locus_tag="KRN00_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBH1827770.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKINAQNIEKQAYEKGYSQGQKNGYEDGYKESYDEYTQKA
                     KDEADFIKNQANLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            4672..5991
                     /gene="fliI"
                     /locus_tag="KRN00_001905"
     CDS             4672..5991
                     /gene="fliI"
                     /locus_tag="KRN00_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBH1827771.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVCATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAMLPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRRVFE"
     gene            6022..6468
                     /gene="fliJ"
                     /locus_tag="KRN00_001906"
     CDS             6022..6468
                     /gene="fliJ"
                     /locus_tag="KRN00_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBH1827772.1"
                     /translation="MELDKNFKFRLQKVLDLKVKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSISKNNDSIQNQKITINYLLALNNSIMDLSEELDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEENLKEQNTNDEFASMSYLRNRQVL"
     gene            6497..7702
                     /locus_tag="KRN00_001907"
     CDS             6497..7702
                     /locus_tag="KRN00_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBH1827773.1"
                     /translation="MKIQADSYNIIKDIGDRKSSSKNKNIKNNKFEDNLYKATDHKKV
                     KDRREVSKQNISSDKPENSDNECHLDEDKSNHLEDENTYEKDCSKNNEALQQLLNLLK
                     DNYKKDKDINTILNNIEKLSISDELKQELKLNKNILNKIANQNSELNKANINSSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            7720..8328
                     /locus_tag="KRN00_001908"
     CDS             7720..8328
                     /locus_tag="KRN00_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBH1827774.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            8355..9338
                     /locus_tag="KRN00_001909"
     CDS             8355..9338
                     /locus_tag="KRN00_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBH1827775.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            9351..9554
                     /locus_tag="KRN00_001910"
     CDS             9351..9554
                     /locus_tag="KRN00_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBH1827776.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            9554..10372
                     /locus_tag="KRN00_001911"
     CDS             9554..10372
                     /locus_tag="KRN00_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBH1827777.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            10362..11057
                     /locus_tag="KRN00_001912"
     CDS             10362..11057
                     /locus_tag="KRN00_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1827778.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            11069..11512
                     /locus_tag="KRN00_001913"
     CDS             11069..11512
                     /locus_tag="KRN00_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBH1827779.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQIDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            11527..11901
                     /locus_tag="KRN00_001914"
     CDS             11527..11901
                     /locus_tag="KRN00_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBH1827780.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEVLKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            11902..12567
                     /gene="fliP"
                     /locus_tag="KRN00_001915"
     CDS             11902..12567
                     /gene="fliP"
                     /locus_tag="KRN00_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBH1827781.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLKQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            12580..12849
                     /gene="fliQ"
                     /locus_tag="KRN00_001916"
     CDS             12580..12849
                     /gene="fliQ"
                     /locus_tag="KRN00_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBH1827782.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMMSLITK"
     gene            12861..14675
                     /locus_tag="KRN00_001917"
     CDS             12861..14675
                     /locus_tag="KRN00_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBH1827783.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYGINETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLINNLMNWTALMIFFSMDGHHVLIRGIRYSFELIPIGKSFIDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIIGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSTDKTEEATPKKKGEQRKKGNIAKSK
                     ELPIAMTLLAFTLLVPTLFSYVVNTLKSSLNYFLSLDFYMNINYSSIEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIVANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIVIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEIKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            14684..16759
                     /gene="flhA"
                     /locus_tag="KRN00_001918"
     CDS             14684..16759
                     /gene="flhA"
                     /locus_tag="KRN00_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBH1827784.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGDLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDDDKTIVVATLSPETEELISNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMSNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            16734..17750
                     /gene="flhF"
                     /locus_tag="KRN00_001919"
     CDS             16734..17750
                     /gene="flhF"
                     /locus_tag="KRN00_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBH1827785.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIQGIFS
                     KKDIELTIGWEKRENVEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLSLELN
                     EEIVESIRIDLQEMKFNGIDTSKNLVEILKKKIKIENQVINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDEM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            17747..18625
                     /locus_tag="KRN00_001920"
     CDS             17747..18625
                     /locus_tag="KRN00_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBH1827786.1"
                     /translation="MIDQAQILRKMAMEKRGLDEFIVENENVPKIITIASGKGGVGKS
                     NLATNLSICLTKLNKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNIISGGSALNHIEDFTEAQRNKFIHSIEQIHDVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKRSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            18639..19340
                     /locus_tag="KRN00_001921"
     CDS             18639..19340
                     /locus_tag="KRN00_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBH1827787.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            19356..19778
                     /locus_tag="KRN00_001922"
     CDS             19356..19778
                     /locus_tag="KRN00_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH1827788.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEKRSNSHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELLLIRSCYKI"
     gene            19763..19948
                     /locus_tag="KRN00_001923"
     CDS             19763..19948
                     /locus_tag="KRN00_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBH1827789.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            19989..20762
                     /gene="flgG"
                     /locus_tag="KRN00_001924"
     CDS             19989..20762
                     /gene="flgG"
                     /locus_tag="KRN00_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH1827790.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            20783..21544
                     /gene="flgG"
                     /locus_tag="KRN00_001925"
     CDS             20783..21544
                     /gene="flgG"
                     /locus_tag="KRN00_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBH1827791.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDSLGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     ADNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            21567..22448
                     /locus_tag="KRN00_001926"
     CDS             21567..22448
                     /locus_tag="KRN00_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1827792.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNECIGSVSLCFPYNGLEALLESISVIEFFDNDVGDDSEEFTQKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            22451..22825
                     /locus_tag="KRN00_001927"
     CDS             22451..22825
                     /locus_tag="KRN00_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBH1827793.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            22857..24260
                     /locus_tag="KRN00_001928"
     CDS             22857..24260
                     /locus_tag="KRN00_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBH1827794.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISTGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDDAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFEKYNQLIRLINKGMYKEAIQGFKLITDQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNNVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKPSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            24376..26313
                     /gene="htpG"
                     /locus_tag="KRN00_001929"
     CDS             24376..26313
                     /gene="htpG"
                     /locus_tag="KRN00_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBH1827795.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDARNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEVVGERVKNYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLLIEL"
     gene            26701..27831
                     /locus_tag="KRN00_001930"
     CDS             26701..27831
                     /locus_tag="KRN00_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1827796.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNPGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGAAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            28058..29080
                     /gene="splB"
                     /locus_tag="KRN00_001931"
     CDS             28058..29080
                     /gene="splB"
                     /locus_tag="KRN00_001931"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBH1827797.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            29262..30173
                     /locus_tag="KRN00_001932"
     CDS             29262..30173
                     /locus_tag="KRN00_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1827798.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            30188..30604
                     /locus_tag="KRN00_001933"
     CDS             30188..30604
                     /locus_tag="KRN00_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1827799.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(30704..31096)
                     /locus_tag="KRN00_001934"
     CDS             complement(30704..31096)
                     /locus_tag="KRN00_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827800.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            31237..31632
                     /locus_tag="KRN00_001935"
     CDS             31237..31632
                     /locus_tag="KRN00_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1827801.1"
                     /translation="MKALEFLNKAGVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            32035..32241
                     /locus_tag="KRN00_001936"
     CDS             32035..32241
                     /locus_tag="KRN00_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827802.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(32398..33129)
                     /locus_tag="KRN00_001937"
     CDS             complement(32398..33129)
                     /locus_tag="KRN00_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827803.1"
                     /translation="MLSKKNVSLIILVIILSLLTAIFIFNNKNTNNKLKEVTKNNEEI
                     VPKNLEGLSIEQLIEIRDKAIDKNLEGLREFGEDSVKKRKDSILNFEFGLVAFVNKNY
                     SNLTEKEKLIRQINIVNYENSINDIMDPSGSFFELANQNYQVNEFLLKNGKDYKEWSY
                     EGLDFLIDHLEELCKFVDFDVKDVIDIIDPTIKTDLSEEQKKSLNDKLKKISSSDTLS
                     EEVKKEIKNWENNLNNLNMNKNNSN"
BASE COUNT        13547 a         3532 c         6001 g        10140 t
ORIGIN      
        1 gacttcttta tttatttaaa ttaatcgcat ttccattaca ttaatacaat aatgtatcaa
       61 tttagtaaga aaactaatat ttttttaatg aagtcccatg aaaatataaa aaaattttaa
      121 tatgtattta aatatttctt cgaaaagttg ctcttttttg taatatagca acttcatttt
      181 ttttattaat aaacaaaata gataaaatat attttgagga ggggtgagtg tgaatacata
      241 tgacattata aaaatgggat tagatgcaac taatctaaga agtcagacaa tagcaaataa
      301 tatagcaaat ataaatactg aaggatataa aagacattat ataacttttg aagaaacact
      361 aaatgatgct atgcctaaaa tagaagaaaa aacagacaat tctaaaggtt taagagtaga
      421 tggtaataat gtagacatag aagaagaaaa agtaaatcaa gcaatggcaa cattacaata
      481 taatgctttg ataagttttg caaatggaaa aatagcaatg accaaatcaa taataagtgg
      541 gaggtaatta gaagatgagt gtgttcagtg gaatgagaat atctgctagt ggattaacag
      601 cagaaagttt gaaaatggat atcatatcat ccaatgtagc taatataaat gctacaagag
      661 gtccaaatgg agaagcatat aggagaaaag ttgtttcatt tgaagaaaac tatgataata
      721 aattaggtat gctaggagta aaagttacat ctgttgaaga tgataaatca cctcttaaag
      781 aagtatatga cccatctcat ccagatgcaa agccaaatgg atatgtagaa tatccaaatg
      841 taaatatatt ggtagaaatg acagatttaa taacagcttc acgagcatat gattctaacg
      901 tagatacatt gaatgctcag aagtctatga tatcaaaagc tttggaaata ggaaagtagg
      961 gataaattat gccaattaca caaattaaca atttaatgca aggtgcaaag ttagataatt
     1021 tgattggaga agcaaagcca ttaactctta ataataaaga agaaaaaaag aattttgaag
     1081 atgtaataat agatactata gataaagtta attttcaaca agtaacagca gatgatatga
     1141 aagaaaaatt tataaaaggc gaagatgttt ctatgcatga agttatgtta ataggtcaag
     1201 aagcacaact atctatgcaa tatttaatag aagttagaaa taagattcat gatgcatatc
     1261 aagaaatgaa taaggtgcaa atttagcctt ttgaacagga gtaataatca atgataacca
     1321 gttttaaaaa taagattaag gagcaagttg ctaaatctag gacaaagata agttctttaa
     1381 aaaagggaac taaaatagca ttaggtatag gggttattgc tatatgttta gcgctagtat
     1441 ttacagcaat atctgcgagc aaaaataagt atgcagtctt attttcagaa ctagatgctc
     1501 aagatgctgc agatatatca gcagagctag agtctaaaaa gatagatact aaggtaaaag
     1561 gaagtacgat ttatgtacct agaacagaag ttgataagtt aaggctggag ttagcgccaa
     1621 gtcttacagg tggttctaaa ggatttgcac taatggatga tagttcatca atagggctta
     1681 ctgatgaaga atttcagatt aagaaacaaa gaatgataca aggtgaaata gaaaaaacaa
     1741 taaagagttt tccacaagtg gaagacacta gagtacatat aacatttgga gagtcatcag
     1801 tatttgagaa ggaggctgtt ccagggagtg cagcagttta tttgatgcta aaaccaggga
     1861 cgactttaga aaaaaaccaa ataaagtctg ttatggcact tatatcagga agcgttacaa
     1921 atataccaga gaaaaatgtt caggttattg ataacaaaat gaatttatta tctgaaggta
     1981 ttttggagga tgaaaatgtt gatgaaaata atcaaccaat aaatagtggc attagtgttg
     2041 ataaaaataa ggcatctgaa caagcattga ataaacaact agaaaagtct attttagaaa
     2101 tgctagaacc gatatttggt aagggaaagg tgaaagctac agtaaatgct gatttaagtt
     2161 ttgatacagc tgaaaaaact gagataaaaa ttgaccctga taaagttgca ataaaggaga
     2221 caaggtcgaa aaattcatct aaatctgctg caaataatgt tcaaggtgta gatgctaaca
     2281 tgaataacca aggaaataac aatggtacta atacagaaga tagtttagat gagagttttg
     2341 agtatgaaac aggtaagatt gaaactcaca ctatagttgc gcctggagaa cttaatagat
     2401 tgacagcttc tgttgcaata gatggaaaaa tagctaaagg tgttcaagct gatgtagagg
     2461 atattgttaa taatgctata ggtatggatg gagcgagggg agatactctt agcgttgttt
     2521 caatggtatt tgacccagaa ggtaagaaag aggctaaaca agagctggaa gagattaaaa
     2581 aagaaggatt taaaaagaac ataataaaag cagttattgg agtagtagca gtaatagcag
     2641 ttggagctat tggatactta atatataaga aaagaagtga acgagaagat atggattatg
     2701 aagatgaaga ttatatttct aaatctgatt ctgttgatag gaaggataat cctctattag
     2761 gagatgatcc agaactgaca ttagaggaag ctgttaaaat gtatgcagaa gaaaagccag
     2821 accaagtaac agagataata aagacttggt taaatgagta agggggatag aaagtgtcca
     2881 cggaaattac aaatgttaat gcgtttgact taagtgatat aaatgaaagt gataagaatg
     2941 agaaggtaga aggtgagggt ttaaaaaaag ctgctgtatt attaatgaca ttaggcccaa
     3001 atgtgtctag tgatataata aaaagcttgc ctgataaaca agttcaaaaa ataggtttgg
     3061 aaattgcaaa tatttcttca atagcttcaa aagaaagaag agaaatctta aaagagtttg
     3121 tagaaataaa tagggcaaaa gattatgtta tagaaggtgg gcttgaatat gcaagagagt
     3181 tattaagtaa tgctttagga aatgttaaag caaacaaatt acttgaaggt atatcaataa
     3241 atacaagtac aaagcctttt aaacatatta taaaactaga tgtaaagaag atattagaaa
     3301 tacttaggaa tgaaagtgca caaactatag ccgttttact tgcacatatg gaaccagaaa
     3361 atggagcaga agttttatca tacttagatt ttgatttaca aaatgaagta gctatgagaa
     3421 taagctcaat gggttcaata tctccagaag taataaaggt aattgaaagt tcattagaag
     3481 ataaattaca ttcaataagt ggtgatgatt ttaatgatta tggaggggtg tctaccttag
     3541 ttcaaatatt gattaattct gatagaaaaa cagaaaagaa tattttggga actattgaag
     3601 aacaaaaccc ggatttagca gctcaaatta aatctcatat atttgtcttt gaagatattg
     3661 tcaagttaga tgatataagc atacaaaaag tgttaaaaga agtgactatg aaagatttag
     3721 tatatgcctt aaaaggtgta gatgatgaga tttcagatgc tatatataga aatcaatctt
     3781 ctagagcagc agatgcactt aaagaagaaa tggaaatggt tggtgttata aaggttacac
     3841 aagttgaggc ttctcaacaa aagatagcta atatcgtaag aaaacttgaa agagaaggtg
     3901 ccataactat tgtaaggaat tttggtggtg actttgttga ataataagat tattaaaagt
     3961 aaaaaagcat tatataaagg agtgctagat ttaaccataa tagataaagt tagagtggga
     4021 gaatcaaatg taaataaaga aaatgattgt agatttaggg atgaggtaat aaaagaagct
     4081 atagaatctg ctgagataaa aaagaatgag atattagaag aagcaaaaat aaatgcacaa
     4141 aatatagaaa agcaagcata tgaaaaaggg tatagtcaag gtcaaaaaaa tggatatgag
     4201 gatggatata aagagtcata tgatgaatat acccaaaaag ctaaagatga agcagatttt
     4261 ataaaaaatc aggcaaattt aatcttatta caagctaatg agaagatgac tgagtacata
     4321 aaagaaaaaa ataaagagat tgtaagactt gctattaata tggccagttc tgttttaaaa
     4381 aagcatttcg aagatgaaga atctatgagt gatttgttaa agcaaattat tcaagattat
     4441 gaaggaagta gttcatttat agtaagatgt aattctttct ataaagataa tatagagaaa
     4501 gagtttgaat tattcaaaga ggaaacatca ctaaaatcaa gtgtatttgt tattgcagat
     4561 gatagtatag ataaaggcaa tgctattatc caaaaggaaa atggaagaat aatagttggt
     4621 attgattgtg ctatggaaaa actaaaagaa gaattgcttg gtgaataaag tatgtataaa
     4681 actgatatat ctatagattt tgacaaaata aataagaaaa tagaaaattt agaactcact
     4741 atatcagaag gtagagtaaa gaagataata ggacttactg tagaagttga aggaataaaa
     4801 gcttttgttg gggagttatg cgttatatac aatcaagtta ataaaccagt gaattgtgaa
     4861 gtagtaggtt ttaaagataa agaagtcata ttaatggcgt tgggagaatt aacattgata
     4921 gcacctggtt gtaaagttat ttctaagggg atacctttaa gtgttatgtg tagtgataat
     4981 ttactaggta aagtacttga tggtcttgga aatcctatag acaactcaga tgctgtttta
     5041 ggagatagat acaacctgaa caatgaacct cctgacccaa tgaagagaaa aaagatacga
     5101 aatataatgg aaacaggtgt aagagcaata gatgcattta ctacttgtgg tgaaggacag
     5161 agaatcggca tatttgcagg aagtggagta ggtaagagta cgactctagg tatgattgct
     5221 aggaatgcaa aagcagatgt aaatgtaatt gctcttattg gagaaagagg aagagaagta
     5281 ctagatttta ttgataaaga tttaggtgaa gagggaatga aaaaatctgt tgttgtgtgt
     5341 gcaacatcag ataaagcccc tctagttagg ttaaaaggtg ctcttactgc tactgcaata
     5401 gcagaatatt ttagagacca aggcaaaaaa gtaatactta tgatggattc agtaactaga
     5461 tttgctatgg cacaaagaga agttggtgta gcaataggag agccaccagc tcaaaaagga
     5521 tatacaccat ctgtatttgc aatgttgcca aaacttatgg agagaacagg gacatcagat
     5581 aaaggttcta taactgcatt ttatacagta ttagttgatg gagatgactt taatgagcca
     5641 atagcagata caacaagagg gatacttgat ggtcatatag ttttatctag agacttggca
     5701 aataagaatc actatccttc tatagatgta ttaaacagtt taagtaggct tatgaatgaa
     5761 attgcttcaa aagaagacat aaaaatagcg tcttttgcaa gagacatgct tgctgagtat
     5821 agagaagcag aagatttgat aaatataggt gcatatgctt caggtacaaa taaaaaaata
     5881 gatgaagcaa tctattatca tgagcatatt attaattttt taaaacaagg gataaatgaa
     5941 aagagttctt ttaatgaaac tataagtagt ttgagaagag tttttgaata aacaattaaa
     6001 aaaatatttg aataggttgt gatggaattg gataaaaact ttaagtttag attacagaaa
     6061 gttttagact taaaagtgaa agatgaagaa gagataaaaa tggaatttgc taagattcaa
     6121 caaaaaaaaa tagatataga gactaattta gaaaacttag aaagtaatta tagcaaatat
     6181 tctataagta aaaataacga tagtattcaa aatcaaaaaa taactattaa ctatttacta
     6241 gctttaaaca attctataat ggatttatca gaagagttgg ataagtcaac aaatgaactt
     6301 gaaaaagcta gaaagcagct tataagcaaa cagatagaga gaaaatcatt agaaaaatta
     6361 aaagaaaaaa agtatggaca gtattataaa gaagaaaatt taaaagaaca aaacactaat
     6421 gatgagtttg caagtatgag ttatttaagg aatagacaag ttctataaga atagtaggaa
     6481 gtgaggatat tattgtatga agatacaagc agattcttat aatattatta aagatattgg
     6541 ggatagaaaa agttcatcta agaacaaaaa tataaaaaat aataaatttg aagataatct
     6601 atataaggca acagaccata aaaaggttaa agatagaagg gaagtaagta agcaaaatat
     6661 tagctcagat aaaccggaaa atagtgataa tgagtgtcat ttagatgaag ataaaagtaa
     6721 tcacttagaa gatgaaaata catatgaaaa agattgtagt aagaataatg aagctttgca
     6781 gcaattactg aatcttttaa aggataatta taaaaaagat aaagatataa acactatatt
     6841 gaataatata gaaaaactaa gtatatcaga tgaattaaaa caagaactta agcttaataa
     6901 aaatatatta aataagattg caaatcaaaa ttcagagcta aataaagcta atataaatag
     6961 ctctaatgat atagaaaatt tagacatagt taaattaaga gaacttttgg aagataatgc
     7021 taataaagat attgaagtaa ttactaaaac tacagaaaat gataccaaaa atatagattt
     7081 gtatagtttt gatagcaata gaatggataa tcttaactca aataaacaga aagatgatag
     7141 ctctgatatt ttggaaaaac tagcaggggt aaatggaaat aagagtggga attttggaca
     7201 agtaataaat aaaaatgttg atatgaataa aattaaaaat gataatgtca atttaaaaca
     7261 gatagaatca aatgtaatgg atgactctat aaaagctatt aagcatatga aaacaaatga
     7321 tatacaagaa ttgacaatta aattaagacc aaaagaatta ggagatatga atatacaatt
     7381 gttaaaagat ggtgaaagta tgagagctgt tgtgactgtt ttcaataaag atgtctttga
     7441 ctctataaat aaaaacatag cagatttaaa gcaacatctt gaacttacta atgtaaatat
     7501 aaaagatgta tcagtgcaaa tgcacagcga taatacaaat acatctgata cctttgataa
     7561 agcatttgaa caacagaata gacaaaataa ccaagaaaac atgagtaaga agaatacaaa
     7621 tgataagcat aataatgtag tcatagaaga tgacattaaa gaaaatacta ttgatgatga
     7681 tagagtagat ttactagctt agtaaggggg aagtattgca tgtacggaat agcaacggct
     7741 ttggcaggaa ctcagggaaa ctataggtca aataacttaa gccaacttga aagaaatatt
     7801 aatgatattg ccaataaaca agttagaagc aaaggaaatc agacagtaac agacaatggg
     7861 actccaatta taggacaagg tgatgatgct gataaagact tgtttatgaa gatacttgtg
     7921 gcacagatgg gtaatcaaga cccaatgaat ccgcaagacc caacagaata tgtgtcacaa
     7981 ttagcacagt ttgcaacttt agaaaagatg tcagctatga atgagaagct agatgtactt
     8041 ttagccttaa gtaattccac tctaataaac tctgctttaa gtatggcaac atcattaatt
     8101 ggtaaagaag tagaagtatc tggggaagag aaagaagatg aaaacattgt aggagtagta
     8161 aagtccacat atataaaaga tggggaagta cacttagaat tagaagtaga tggaagtgac
     8221 aaaactgtag gtgttaaata tgaaaaatta cttaaaatag gagaggtaga tgaaaattca
     8281 ggagaagaaa atgattcttc agaacacgaa tctccagaag aagcataata ttaaatgaga
     8341 aaagaggtaa attcatgata aaagcaatgt attcaggtgt aagtggaatg aaagcaaatc
     8401 aaacaaaatt agatgtaata ggtaacaatg tagccaacgc tggaactact tcttttaaga
     8461 aaagttcagc tagaataaca gattcatttt atcaaactgt actatatgca agtgctccaa
     8521 cagctgcatt aggaggaaca aacttaggac aagtaggtgt aggtagtaag atatcaagta
     8581 taaataaaga tatggtacaa ggaaatgtac aaccaactaa tagaccatct gatttaatga
     8641 tagatggaga tggatatctt ccagtagtaa gacaaggaac agttatgtat acgagagatg
     8701 gttcttttaa tttagataca ggatttaaag cagctgatgg tgctttgaag aatattaaag
     8761 gtggaagact tgtaaatggt gatggatata tgttacaagg tatgatttat gatggggaat
     8821 ataaagctga tactggagaa tttgttaaaa agggtgatgc taaaggaaaa gagcctattg
     8881 taataccact tcaaagtata agtcctaagg atggaacagt tcaaaatgta ctagagtata
     8941 atatatcaaa ggatggaaca gtagaatttt tattgagtga tggtcaaaga actcaatttg
     9001 tctatgatat acctgatggt gctaaggtag gagatacacc tgctggaata gataaattaa
     9061 aaggtacaat acaaaaagtg caaacatatg cattccaaaa tccagcagga ctagatgcag
     9121 aaggaggaaa cttgtttaaa ccatcagcaa actcaggaga cccacaaata gcaggagcta
     9181 caggcacaat aatacaaggg gcaatagaag cttccaatgt agatatagca gaagaattta
     9241 cagaaatgat aatagcaagt aggtctttcc aagcaaacag taaaataata tcgacatcag
     9301 acgagatact tcaagaaata ataaatctta agagatagta ggtacatatt atgataagag
     9361 taacggattt aaacggaaga aaatacatat taaattcaga ccttatagtg aggattgatt
     9421 ctgtaccaga aagtaggatt ctccttacaa caggagaaaa aaaccttgta aaagagtcgg
     9481 tagatgagat agtagataaa gtaataaagt ataaaagaaa aataaatgta ggttatatta
     9541 ggagcgaaaa ataatgaaaa aaacagattc actgacattt attggactaa tagtatctac
     9601 agtattagtt ttagttggtg ccgcaaaagg aagtagttca gggttaaaga atttttttga
     9661 tgtttcatca atattaatca cagtgcttgg ttcatttgga gctctaatga ttacatttac
     9721 tatagatgat ataaaactta taaaaaatgc attacaatac tcatttaaga caatgagtgt
     9781 atcaaagtta gatttactag aacaatttaa aacactttct aaaaaagcta gaaaagaagg
     9841 tcttttatca atagagagtg atgtaatggg aatagaagat ccatttatga agaaagggtt
     9901 agagctgtgt attgatggat tggaaatcaa tgagataagg tccatcttag aactagagat
     9961 agattctgtt gaagatacaa ataacagata ctctaaacta tttaaaactt ggggaacctt
    10021 tgcacctgct tttgggatgt tgggaacact aataggttta atacaaatgt tagctgacct
    10081 tacatctcca gatttaatag catctggcat gggaaaggca ttaattacaa cgttttatgg
    10141 ttctttactt gccaatatcg ctttgaaccc aattgcatat aatatagatg agaagactga
    10201 aaaagaaatt tatgtaaagg aaatgatgtt ggaaggtata ataagcatac aatctgggga
    10261 gagcagtata gtagttgagg aacgtttagc cacatacctt tcaaacaatg agaagttaga
    10321 aattatgaaa tccaataaaa atacagaaag agcaatgagc aatggcgcgt aaaaaaaata
    10381 agaaaaagga tgagataaat ccagatgcat ggctggctac ttatgcagat actataacac
    10441 tgattcttac atttttcgta ttattgtatg caacatcagt tgtagatatg gaaaaattta
    10501 aaaacatagc agatgcgtta aaaggtcagt tttctgggac aagtatattt agtacgggtt
    10561 caagtacaag tgagaaatct ccaatagaca gtgttttagt ggataaaaat gataaatcaa
    10621 atttagaaca ggatttaaaa gataaagtta ataattctaa cttacaaaat agtgtaacag
    10681 tcaaagatga tagtagaggg attttactag agttagatga ttcaatttta tttgactctg
    10741 ggatttctga gttaaaagta gatagtaaag ctactcttaa taaagtatat gacatgataa
    10801 agatgatgaa aaataagata gttatagaag gccatactga taatgtacct gtaaaatcaa
    10861 gtacacatga atccaattgg gatttatctt ctagtagagc agtaagtgtt gtaagatact
    10921 ttgtagaaga aaagggcatg gaccctagac tattttcggc aacaggatgt ggagagtatc
    10981 aacctttggt ttcaaatgaa acagcaaagg gaagagctga gaatagaaga gttaatatac
    11041 ttataactat tgactaggag gaagaggttt gttcaaaaat aaaaaaatta ttataattat
    11101 tttgatactg attattttct cagcaggagc aggttttttt atattaggag aaggtggaaa
    11161 taaacaaatt gacaagattg caggtttgtt tattccaaca gggaaaggca aagatgaagt
    11221 aaagaccgag aatcttgact tagaagagat ggtattgaag ctagctgatg aaggtgtaag
    11281 atatttaaaa gtatcaataa ctgtatctta tgattcttca tataaagata tagaaaaaaa
    11341 tacgccttta attagggata atattataaa ttgttttatg gcaaaaaggg cagatgattt
    11401 tactgctgat aatttaaaga atataaaaga agaaattaaa aatacattaa atatacaact
    11461 aggtgaaaat gtaattcaaa atatatattt cacaaatata gtagtgcaat aaaaggatgg
    11521 taagacatga tactttattt actaaaaata ttaatatgta tcccaataat tttaatattg
    11581 atagtcttat ctttaaaaat tagccaagga actttattaa aaaaatataa tgataaatat
    11641 gtaaaaatac tagatattgt aaatataagt aaaaacaata gcataataat tttaaaaata
    11701 ggtgaagaag gatgcattat ggcatcttct tcttctagca tgagtaaaat aaaagatttg
    11761 accaaagaag aagtattaaa aatagaaaac gacattaaag aaagaaattt taaaattcaa
    11821 gattttaaaa tggaaagaat taaaaagaaa tatgatttca gtagatatat tggaaaattt
    11881 acaaaaaagg aagataagta aatggaacta ttatcaaaat tacctttggc tgatgtacca
    11941 tatacaagtt caatgcaatt gtttttattt ctaactgcat taatgttttt accatttgta
    12001 atgttcatga tgacaagctt tgtcagaata gttataagtt tatcattttt gaaatcagca
    12061 ttaggagcac agcaagcaat tccaagtcaa attttggtag gacttgcaat agtattgaca
    12121 atatttataa tgagaccagt attaaatgag ataaacgaaa aggcattaca accatatatg
    12181 aaagaagaag ttactatgga agaagctatg aaggaagcag aaggacctat taaagaattt
    12241 ttattaaagc aaaccagaca gacagattta gatttatttg tagagcaagc tggtttaaaa
    12301 gaaaagaaat taactcgtga aaatatacca ttatctgttg tagttccagc atttgctata
    12361 agtgaactaa aaactgcttt tcaaataggt tttttaatat atataccatt tttgataata
    12421 gaccttgttg tggcaagtgt tttgatgtct atgggtatgt ttatgttacc tccagttatg
    12481 atatcattac catttaaatt attattattt gtaatggtgg atggatggaa cttgatagta
    12541 aaaacattga tattgggatt tggataggag aaaaatagta tgagtgaatt tatgataatg
    12601 agtgttctta aaaatggcat gtttacagga gctatgattg cagctccagt gctaattgtt
    12661 tctcttgtag tggggctttt aataagtgta tttcaagcca caactcaaat ccaagagcaa
    12721 actttgactt ttgtaccaaa actaatagca attcttttag tagtagctat tggtggaagc
    12781 tggatgttac atactcttat tagctttact tcggagatat tcaatatgat gtctctcata
    12841 actaaataag taggatatat atgatttttg tatttattag aatagtagca ttctttggaa
    12901 cattaaggat actatttcca gctggtacac ctgctttatt taagtcgctc tttgcaatca
    12961 ttatatcaat cttgatttca agtactatgc aaattgaata tgcaacaaat atagacaaca
    13021 ttgtattgtt taccttatat ggtataaatg agaccataac tgggattatg cttggatata
    13081 taaccaatct atgtttttat agtatcagaa tggctggttc tatgatggac caacagatgg
    13141 gattatcaat gattaatatg tttgacccaa attcaatgac tcagacaact ttaatcaata
    13201 atcttatgaa ctggacagca cttatgatat tttttagcat ggatggtcat catgttttaa
    13261 ttagaggcat aaggtatagt tttgagttaa ttccaatagg gaaatcattc atagataata
    13321 atatagatta tataataaac atatttgtgc agtgcttttt aactggattc aaaatagcaa
    13381 tacctattgt actttgtctg cttatggcag attttatatt agggcttata tcaagaagtg
    13441 tacctcaact aaatgtaatg ataattggta tgccattaaa aatactggtt ggtattgcat
    13501 tatttatcat atcaatacct ttaattgtca atcaaataag tcatttatta agtcaaatac
    13561 caaagatgta tgagggaact tttgcactag ctcctatgtt ttttatgggt tcaacagata
    13621 aaacagaaga agctactcca aagaaaaagg gagaacaaag aaaaaaaggt aatatagcaa
    13681 agagtaaaga attacccatt gcaatgactc tacttgcatt cactttatta gtacctacat
    13741 tattttcata tgtagtgaat acacttaaat cttctcttaa ttattttttg agtctagatt
    13801 tttatatgaa cataaattat tcaagtatag agaaattagt tatagcagga ttaatggatt
    13861 tttttaagat atttttacca atagctattc cattcttagt tttaggtata gtcgcaaacc
    13921 tatttcaagt aggaatactg tttactggtg aaactttaaa acccaattta tcaaaattaa
    13981 atccaattag tggattcaaa aacatgtttt ctatgagaag tttgtcaacc ttaataaaag
    14041 atacagcgat tatatctatt ttggcttaca taggatatac attcttccaa gataattatt
    14101 tagatatatt aaagctaggt aacatatacc tgccaacttt aatgtacaca gttaaagatt
    14161 tagtatattc aatattaagt aagatttgtg tagctatgat agttatagca gttgcagatt
    14221 atgtttatca aagatacagt cataaaaagc aacttagaat gacaaaacaa gaagttaaag
    14281 atgaatataa aaactcagaa ggagacccag aaataaaagc taagataaaa caaaaacaaa
    14341 gacaaatttc gtctcaaaga accatgcaag cagtaccaag tgctactgta atagtaacca
    14401 atcccaccca cttatctata gcagtgagat atgaaaaagg gaaagaccaa gctccagtag
    14461 tggtggcaaa aggtgcagat tatttagctt ttaaaataag ggaaattgca aagggaaatg
    14521 acatacctat aatagaaaac aaacctattg ctaggttgtt atataagcaa gtagaaatag
    14581 accaagaaat tccagaggac atgtatcaag cttttgcaga gatattagtg gcagtatata
    14641 aaatcaaaaa tagatacaaa gtccccaaaa ggtaggataa gtaatgaata agtttaattt
    14701 aaaggaaaat atggatgtaa tagtggcatt tggtgttgta gggattgttc ttatgatgat
    14761 agtgccatta cctacattta tattagatat tttactggca attaacataa gtttatctgt
    14821 gctaatttta ctaatgacat tatttacaac aaatgtactt gatttatcta tatttccaac
    14881 agtgttactt gtgacaacac tatttagatt gggattaaat ctttcatcaa ctagattgat
    14941 tttaacacag ggatatgcag gtgaagttat agaggcattt ggaagttttg ttgtaggtgg
    15001 aaattacgta gtaggaataa ttatattctt aattatatta attgttcaat ttgttgttat
    15061 aaccaatggt tctggaagag tatctgaagt aacagctaga tttacgttag atgccatgcc
    15121 aggtaagcag atgagtatag atgcagattt aaatgcagga gttatagatg acaaaactgc
    15181 tagaaaaaga agaaaagagc ttcaacaaga agcagatttt tatggttcta tggatggagc
    15241 aaataagttt gtaaagggag atgctatagc aggtcttata gtaacggcaa taaacataat
    15301 aggtggaatt gtaataggag ctgtaatgct gaatatgact cttatgggtg cagcacagac
    15361 atatgtaaga cttactatag gggatggtct tgtaagtcag atacctgctc tattaatatc
    15421 tacatcagca ggtataatcg tgacaagagc ttctactgat gaaaactttg gtgacttagt
    15481 aggtaaacag ttaaccgcaa taccaaaagc agtaatgatg actggttgtg ttctaatcgt
    15541 acttggtatg atgcctggat tacctaaacc agcatttttt tcactaggta taggagctat
    15601 agcagcaggt tactttttag gaagagaaaa gaaagatact ttagaagatt tggagtttga
    15661 aaaacctgat atggtaaatc cagataaaaa tgaagtagaa gatgtaacaa atttaataaa
    15721 tgtagaatca atagaagtag aaattggata tggtttaata tccttagctg atgaatcagc
    15781 aggaggagat ttacttcaga gaatagcatc aataagaaga caatgtgcaa tagacatggg
    15841 tatagtcgta caacccataa gaataagaga taacttacag ttaaatccaa accaatacaa
    15901 tataaaaata aaaggaaatg tagttggtgg gtatgagata atgcctaata tggttttatg
    15961 tatggatcct atgaatcaag gatttagtat atttggaata aagacaattg aacctacttt
    16021 tggaatagag gcactttgga tagaaagtga caaggtagaa gatgcagagt taaagggtta
    16081 tacagttgta gattcatcca caatacttat aactcactta ctagatataa taaaatcaaa
    16141 tgcacacgaa ttactgggaa gacaagaagt taagactatt atagatgcag caagagaaaa
    16201 ttatagtgct gtagtagatg aattgatacc agatttgatg acacttggtg aaattcaaaa
    16261 agtacttaaa aatctgttaa gagaaaaagt aaatataaag gatagagtta caatacttga
    16321 aacgcttgca gaccagtcta gaaatacaaa agatatagag cttcttactg aatatgtaag
    16381 aatagccttg gctagaagta tttgtaataa tttagttgat gatgataaga caattgtagt
    16441 ggctacattg tctccagaaa ctgaagagtt gatatctaat aatttacaga ggtctgtaaa
    16501 tggaacttat ccagcagttg acccagaaaa tacaaataaa atatttgaaa gtatacaaga
    16561 agtaatgagc aatgtatatt tcaatcataa tataccagta atagtagtat caccaaagat
    16621 aagagctcca tttagaaaat tagttgaaat tgtatatcct aatttgactg tattatcatt
    16681 aaatgaaata cctaacgata ttaaaatcaa agcagaaggt gtggtgagca tatatgatga
    16741 cgaaaaagta tacagctaac acaattcagg atgctatgaa tctagccaaa atggaattgg
    16801 gtgacaatat tacattaata gataaaaaag aagtaagaaa gtctggaata caaggtatct
    16861 tttcaaagaa agatattgaa ctaactattg gatgggaaaa gagagaaaat gtagaacaaa
    16921 aagatttaaa acgagagata gaacaattaa agtcaattat taacaatatg gggtttgata
    16981 ataagaatga taatgatata gataaaatat gtaaaaatct actaagttta gaattgaatg
    17041 aagaaattgt agaatctata agaattgatt tgcaagaaat gaagttcaat ggaatcgata
    17101 caagtaaaaa tttagtagaa attttaaaga aaaagattaa aatagaaaat caagtaataa
    17161 atggtaaaat tgctctagtc ggaccaccag gagtaggtaa aacgactaca atagcaaagt
    17221 tagccgcaaa attagttttt gaagaaaata aaaaagtagg agtaataact atagatacat
    17281 acaggattgg tgctgtagaa cagttgaaga tatatactga tataatgaat attcccttta
    17341 aaggggtaat aagtcctgat gaaatggaat tggcacttga cgagatgaaa gattgtgatg
    17401 ttgtattaat agatacaaca ggtagaggct ataaaaactc tatgcaaata ctagaaatca
    17461 aaaatcttat agataaagct gaaactgata atatacattt agttttgaat tgtacaacaa
    17521 gagaaagtga tacaaaagca attatagatt catatagaaa tgtgaatttt aaaagcttaa
    17581 taattacaaa gttagatgaa acaataacat atggctcaat atttaacata atgaattatg
    17641 cacaaaaacc aatatcatat attacaacag gacaaaatgt tcctgatgat attataaaac
    17701 ctaatgaaga taagattata aggttactat taggagttga aagtatatga tagaccaagc
    17761 tcaaattttg agaaaaatgg caatggaaaa aagaggactt gatgagttta tagtagagaa
    17821 tgagaatgta cctaagataa ttacaatagc ttctggtaaa ggcggtgttg gaaagagcaa
    17881 tctcgctaca aatttgtcta tatgcctgac caaacttaat aaaaaagttc ttatattaga
    17941 tgcagacata ggaatgtcta atatagatat aataatgggg gtaaatgtaa aagggactat
    18001 aattgatgta attaatggtg aaaaaaatat agaagatata atttcacaga ctaagtatgg
    18061 tgtaaatata atatctggag gttctgccct taatcatata gaagacttta cagaagctca
    18121 aagaaataag tttatacata gcatagaaca gattcacgat gtggatttta taataattga
    18181 tacaggagct ggtatgagca aaagcctatt gtcatttata tactgtagta ctgaattttt
    18241 cttaataaca actccagaac cgacatcatt gactgacgca tatagtttat taaaagctat
    18301 aagtaatttt ggcataaaga gaagtgcaaa tataataatc aatagggtaa ttgatttaga
    18361 agaagcaaaa tctacataca aaagaataaa aatggttgtg gacaaatttc taaaccttaa
    18421 tctagaattg tatggatata taatagatga caaaaaagta agtttatgtg taaaaaaaca
    18481 gataccattc attttagaat atcctacaag tattgcatca aaatgtatta tagccatagc
    18541 aaagagaatg gtaagtcagt caagagaaga tattgttgat aataaaagtt ttctaagaaa
    18601 gatgtttagt atatttaaaa gctaaggagg cgtagttaat gaatagagaa gaattaataa
    18661 aagagaatat gcctcttgta aagagtatag caagaaaatt ttttatacca gggaaaggtt
    18721 ttgaatatca agacttagta aatagtggag tcattggatt gattgatgca ataaataaat
    18781 ttgatgctga aaaaggggca aagttttcta gttactctta tataaaaata aaatctgcta
    18841 tattagatga aattagaaat caaagtccaa tttctaaaca taatctaact aaagtaaata
    18901 agtataatag agtggtagaa aagttgcaat ctaaattatt aagagagcca acttcatatg
    18961 aaattgcaaa agaattaaag gtttcagaaa aagaacttca tgatatcgaa agtaatatag
    19021 atatgttaaa tattgtatca ttaaactatg taatctttga agatacaaat gaaactgtac
    19081 aagatgtaat aagtgataga gaagaggaag ctccagaaaa tataatagaa gaagaagaaa
    19141 agttagagat tctatccaaa gcaattagta atttaaatga aagagaaaaa ttaatacttt
    19201 cactgtacta ttatgaagat ttaaatctaa aggagatagg gaaagtgcta ggtgtttcag
    19261 aatcaagagt ttcacaactc cacagaaaat caataagaaa cttaagaaac aagataaaag
    19321 aacttaaata ttctatatag atggtgattg ataagatgat acaaattata ttaatagtag
    19381 tatctatttt aataatagta actatagtta taaatttaca taaggaatca aaaaataaag
    19441 ataacagata ctttgataaa atatttgagc aagaatatga agcaaatgat agattaataa
    19501 ttgcagaaaa aagaagattc tttttagaca aagtacttgc agaaaaaaga agtaatagtc
    19561 atataaaagt ttatgaaaat tataacctaa taaaggctaa tgaagaaaga aaggaaaaca
    19621 tatttataga atcaaaaaag gaagtaagac aagaaaatga gttatctctt aaagtgaaac
    19681 atcttataag ttcaggttat gatgatgtgg aaatatgtaa gatgctagat attggaaagg
    19741 gggaactgtt attaataagg agttgttaca aaatataagg atattattat gtgataaaaa
    19801 agtattctta ggaataggta ttggtatatt aatatcaact ttatgtataa tgctttttag
    19861 taataatgat atgagtaaag cagagataga aaaaaaggcc agagcgttag gcatgaaata
    19921 tacaagtgag atgaaagttt tagaatagat gatactgttt agacatttac aaaaaaggag
    19981 gtcataatgt gataagagga ttatatacag cagtttctgc tatgataact aatcaacaaa
    20041 agcaaaatgt tgttgtcaat aacctagcta atatggatac aaatggatat aaaagtaaac
    20101 aacttttgac taaaagtttt gatgaattaa agttggaggg ttacaataac tacgcaaatg
    20161 gaactaaaca aaagcagatt ataggcgata taagtccagg tatttctatg gatgaaacta
    20221 tcacaaattt taatcaagga cctataaaaa ctactgataa taaaatggat gtagctattc
    20281 aaggtaaggg attttttcta gttagtgatg cagctggaaa tcaattttac actagaaatg
    20341 ggaacttcag aacagacaat caaggtgacc ttataacaag tgaagggtat tatgtacttg
    20401 ggacgaatac tgctactggt gctgtaggtc atataaatgt aggaaatcaa aaatttgaag
    20461 tggcaaaaga taatacaata tcactagacg gaaatgctat gtataaattt aatattgtag
    20521 attttaataa ctacaataac ttaaaaaaag aaggagataa cttatattct ggaggaggag
    20581 ctatgaaagt aaataatgca cttacaatac aaagtgcgat agagtcctct aatgtagata
    20641 tggtatctga aattaataat atgatgacaa tatcaagaga atatgaggca aatcaaaaga
    20701 taattcaggc tatggattct aaattagcaa aaatagcaag tgagattggt tcagtaagat
    20761 aggtaatagg aggtgaattt ttatgtacac aatgttttat actagtaaaa cagctttatc
    20821 agcaaatcaa agtaaactag atataatatc taacaatata gcaaattctg attcaacagg
    20881 atataaaaaa ataaatatgg aatattctga tttagtggat gaagtactaa atagaccatc
    20941 atatcctaca aatggcaatg atatatcgac tggaacagga gctaaggcaa cagctcccat
    21001 gagaaattat gaacaaggtg cattggctcc tacagatagt aagagtaatt tggcaataga
    21061 tggagaagga ttctttagag tgataagaaa agatggtaca tatgcatata caagaaatgg
    21121 tggatttaat gtagattctt taggtaagat tgtagatgat aatggaaata tattagatgt
    21181 ccaatttgat gcaggatata actataataa tacaaatata gatagtacaa acctgacagt
    21241 ttcaagaaat ggagagctat tcgcagataa taaaaaaata ggaaaaatca acttatatca
    21301 acctatagga actcaaaatt ttatatctga aggagatagt ttattcgtcg caactgatgc
    21361 agcacagatt aaacaagttg agaaagtcga tatagttcaa ggctatagag agaggtcaaa
    21421 tgtttcttta caagaagaat ttgttgactt aatagccact caaagagcat ttcaaatgaa
    21481 ctcaaaggga ataaagacag cagatgaaat gtggcaaata gcgaataatt taagagctaa
    21541 ataattatgt aaggtgagga atattcatga atgatatgaa agagtacgat tttggcaaac
    21601 ctcagagtta ttcaagagaa aatttaactt gtttaaattt tttattagct gaattttgta
    21661 aaaaatataa aaactatata atttatgaac ttaagtgtaa ttctagtatg gttgttgata
    21721 gtatagacca agtaaattat cagacttttt tagatagagt aacttcttca tgcgtagtag
    21781 tacaaaatgc aatggaacct gttatgaaaa acttttcttt tagaatagat agaagtgtag
    21841 ctgatatgtg gattgatata acttctggag gaactggagt tgtaaaggat aatgatagag
    21901 agcttacaga acttgataaa aaagtgcttt tacaccttat ggatgattta gtaagaaata
    21961 tgcacttatt tgagggtttt gaaaatatac aagtattgga tacacataca catattaatt
    22021 tgccacaatt atgttctcca actgcaccag tatgcgttgt agatttaaaa gtgctaaatg
    22081 ataatgagtg tattggaagt gtttctcttt gttttccata caatggttta gaggctctgt
    22141 tagaaagtat atctgttata gaattttttg ataatgatgt aggagatgat tcagaggaat
    22201 ttacccaaaa aatctataat agtgtatcta atatagaatt atcagttatt gcagagatag
    22261 gaaaagtatc aattaatgtt gaggatttac ttaaactaga agttggagat gtaatagtaa
    22321 caaataaaaa aataaatgat tatatagata tatttgtaga aaattcaaaa tcatacacag
    22381 caacaccagg atttatatca agtaaaaaag gtgtaaaaat aaatgatgct gttggaaaag
    22441 aggtgtagtt atggacaata gtaatcttat ttcagatgaa gaagcaaaga tgttattaaa
    22501 tgataaagtt gaaagtgaag ttgatggaga tgatgagtta gccttagatg tctctgaagt
    22561 taatcgaaat aatatacaaa ggatacttga ccttaagtta gaattatctg tagttatagg
    22621 aagaactaag atgactctaa gagatatttt aaatttacat aaaggttctc ttattgaact
    22681 ggatacttta gcagaccaag atgtggaaat actaatagat aataaggttt tggcttatgg
    22741 aaaagtagtg gtggtagatt taaattttgg tgtaaagata acaagtatag taagtgaaga
    22801 agacatggta aaatctcttg tttagagata acatcaatta atacttaagg catgaggtgg
    22861 tacttatttt aaacttaaat gatataaaaa aagatatact aaaactcaat aaaaaagact
    22921 catgttctct atataatgaa tctattaata atataaataa taattgtata tcaactggat
    22981 taaaattttt aaaacaagca agagatttaa acccagatga tgttgatata ttaaatctca
    23041 caggtcttgt aaacttacta aaatgtaatt ttgatgatgc tgtagaaagt ttctataaga
    23101 gttcactttg tgaaaaaact gctctgtgtg aaaagtatat aaacatgctt acatctgagg
    23161 agtttttaat tttctttgaa aagtacaatc aacttataag gttaataaat aaaggaatgt
    23221 ataaagaagc tatacaaggg tttaaactca taactgacca atactgtgat ttaatagaac
    23281 cttatgagtt acttgcctta ctgtatgaca aggaagaaga atatataaaa tttgatgaat
    23341 gtttagaagt attgaagatt attgataagg aaaattattt attaaatcaa gaaaataaca
    23401 cattagatat gtataatagt gctaatatac aaactaaaag taatataaaa gtagatgatt
    23461 ataagaatga gttcttacat aaaagtagta gtaatcataa aattaatgat tataataatg
    23521 taactaaaga aaagagttca agcaaaaacc agaaaagttc agattctaat aagaaaaaaa
    23581 gtattaaaaa aaataagtac ctatatatag ccataatatt aggaatatta ttagtaggac
    23641 aaagtatata tagttcttat aagatgaata atttaactga taaaatatct aaaaataatg
    23701 aaactaaaaa tgaagagtca atagattcta acttgactaa gaaagaaaat aatatagaag
    23761 aaaatgaaga tatgagtaag gcttctaata taaataagag taataaaaac attaataaag
    23821 aggatgatgt aaaatctaaa aaaaatactg tagaaaatga agatgataaa gattctgact
    23881 tatttacaga ggatgaattg atgtctaagg cgaatacttt aaaatcagaa aagaaaacta
    23941 aaccttctat acaactatat aagaaagttg cagatatagg tgaaaataaa ggaaatacat
    24001 ctgaagcaac ttatcaagtt gctattctca gtgaaaagtt aaaagactat aaaactgctg
    24061 aagaatatta taaaatgtat gtagaaaatt actcagaaaa agatgcttat tttgatgaat
    24121 cttattataa tttaggtatg atgtactata acaatggtga tttaaaaaat tctaaattga
    24181 cattaaagaa gttggttaat aaggtaccaa atagtatgta taataattca aaagtaaaag
    24241 aaattttaaa agaagaatag ttaaattaga taagaaaaat aaattatttt attttaaaat
    24301 aatatgatta taatatattg acataccatt ttaaaaaatt taaaatatta attataaaat
    24361 gaggagggat aaaaaatgga atttgaaaaa gggagtattt caattcatac agaaaatatt
    24421 tttcctataa ttaaaaaatg gttatactct gataaagaca tatttataag agagcttata
    24481 agtaatggat gtgatgcagt aagtaaacat aaaagacttg tatcactagg agaaatatca
    24541 gaaaataagt catcagatta taaaattaca gtatctgtaa ataaaggaga aggtacactt
    24601 aaatttattg acaatggaat tggtatgact gaagaagaga taaaaaaata cataaatcaa
    24661 gttgcttttt caggtgctga agatttcttt aataaatata aggataaaat ggaagagtca
    24721 aatgatataa taggtcattt tggattagga ttttattctg catttatggt gtctaaaaag
    24781 gtacaaatag atacactttc atatacagaa ggagcgactc ctgtaagatg gatatctgaa
    24841 ggtggtacag aatacgaaat atctgaatca gatgctagaa atgatagagg aactactata
    24901 acactattta ttgatgatga tagtaaagaa tttttagatg aatttactgt aagaggaata
    24961 ataaataaat actgttcttt cttaccagta gaaatatatt tagaagatgt tgaaagatta
    25021 gaaagagaag ctaaagaagc agaagaaaaa gctaaaaaac aaaaggaaga tggaaaagaa
    25081 gagattgtag atgcaaaagt aattgagcct ttaaacgaca ctaatcctct atggttaaaa
    25141 tctccaaaag actgtactga tgaggagtat aaagagtttt atagaaaggt attcaatgta
    25201 tttgatgaac ctttattttg gatacattta aatgtagatt atcctttcaa tttaaagggt
    25261 atactttact tccctaaatt aaaaaatgag tttgaactga ctgaaggaaa agtaaaatta
    25321 tacaacaatc aagtgtttgt ggctgacaat ataaaagaag ttataccaga atttttactt
    25381 ttattaaaag gtgttataga ctgtccagac ttaccattaa atgtatcaag aagtttctta
    25441 caaaatgaca gggatgtaag caaaatttct aaacatataa ttaaaaaagt agctgataag
    25501 ttaaaatctc tttgtaaaaa tgaaagagaa gaatacaata agttttggga tgatatacaa
    25561 atatttatta aatatggttg cttaaaagat gaaagtttct atgagaaggt aaaagaatgt
    25621 atattattca aaactattga tgatgagtat ataacattac aagattattt agaaaaatgt
    25681 aaggacaaac atgaaaataa ggtattttat gtaagtgata aggaacagca atctcaatac
    25741 attaaactat ttaaagaata cgacttaagt gctgttgtct taaactcatc aatagatact
    25801 cattttattt catttatgga atataaagag aatggagtta agtttaatag aatagatgca
    25861 gacctttctg atgtattaaa agataaaaat gaaaataaag atagtgaaga aaacaaagaa
    25921 gagatagcta agatagaagg tctgtttaaa gaagttgttg gagaaagagt gaagaattat
    25981 tctgtagaag gattgaaaaa tgaagacact ccagctatgg tgttagtatc agaacaatct
    26041 attagaatgg cagaaatgca gtcaagattt gctggaatgg atttaggaat gaattttgaa
    26101 gaagaaaaaa ctcttgtaat aaatgagaac agtccaataa tcaaaaaatt ggtttctctt
    26161 aaagatgatg aggaaaagaa agataagatt acgcttattt gtaaccagat agcagattta
    26221 gctttacttt ctaataaaga attaaagcca gatgagttag attcatttgt acaaagaagt
    26281 aataagctta tgagtctttt gatagaatta taagattgaa tttgaataca ttgaagcaaa
    26341 tttataaaaa gtattcaata tcagtgataa gaaagaagtg tctcaaaatg aacttttcag
    26401 ttcatgaggc gcttttttta tgtgaaatta aatttatttt aatcatttca acaatgaaaa
    26461 atatatttat ctctattttg agacagaccg ttctttattt ttttatcttt ggttaatttt
    26521 taaatattta agtaggttct aataaaaaac tctatttagt taaatatagt taacttgata
    26581 tataataaga taatacatat aattaagtaa aagattgttt tttagtttat gtttaaatac
    26641 ataattacac tttgttaaaa acataaaatt attactaaag tagaaatagg aggttttagc
    26701 atgaatttta attataattt gccagtaaat atcttatttg ggagaggcag aattaatgat
    26761 gtgggaaaag aagtatctaa atatggcaaa aaagtattga tagtaacagg taaaaatagt
    26821 acaaagaaaa ctggattact tgataaaaca atagatttac taaaagactc taaaatagaa
    26881 tatgaagttt ttgatagagt agaacaaaat cctcttataa ctactatata ttcaggagta
    26941 gaaattataa aatcaactgg atgtgattgt gttttaggtc ttggtggtgg aagcattatg
    27001 gatgctgcca agagtatagc tttttcttat aaaaacccag gagatttaaa tgattatata
    27061 tttggaatta gacaaggtga agaagcttta cctataatct tagttccaac aacatcaggt
    27121 acaggtagtg aaggaaattg ttttgcagta cttacaaatt cagaaactaa agataaaaaa
    27181 tctataaaga agaatagtat gtatgcaaaa gcatcaataa ttgacccaga acttatggtt
    27241 acaatgccaa aacatataat tgcatcagtt ggatttgatg cacttgccca taatatggaa
    27301 gcatatcttt ctaatggaag aaaccctctt gcagatgtac aagctattta tgggattgaa
    27361 cttatatcag aaaacctaat aaaggtatat aatgatgtta atgatttaga agcatgggaa
    27421 aaaataacac ttgcaagtac tattggagga atgacgattg gtgcagcggg tacagccttg
    27481 ccacatggaa tggagcatcc tgtaagtggc cttagagatg taatgcatgg aaaaggactt
    27541 gcagctttga ctcctactat tatagaaagt tcatgggata gtgatattga aagatttggt
    27601 aatatttcaa aggtattagg aggaacttgt gcagaagatt gttcagatgc aattagaaat
    27661 ttccttaaaa aaatagattt agatataaaa ctaagtgatt taggtattga aaaatcagat
    27721 atagattggt taactgataa ttgtatgaaa atatcagttg caaatattaa gagacatcca
    27781 aagtatttta ataaggaaca aataaaggaa atgtaccata agtctttata atttgacttt
    27841 acatatttag ttttatataa aaattataaa ttaataataa aaaattataa gtaattaata
    27901 gtaaaaaaat tgtgtataga agttatatat ataataaact tgtcttaagc ttttatttta
    27961 ctttctaata aataaaggag tttaaaaaag ggaagattaa ttaagtaata ttttataaaa
    28021 ttcttcgatt taaaaacttt aagtagaggt gaaataaatg tttaatccca aaagaataat
    28081 attcgaaaaa ggaactttag acactgatgt gggtaaaaaa atatacaata aatttagaga
    28141 taataaagat gtagagataa ttaatatatc atcaaatagg attaaagaac atattccagg
    28201 tgaaaatcta tatgaacaat atagaagtgg gaagcagact atggtagttg ggattagaaa
    28261 aagtctgaag tttcaaacat gtaaaccttc tgctaattat caactaccac ttgtcagtgg
    28321 atgtatggga agatgtgagt attgttattt gaacacacaa ttaggtgata aaccatttat
    28381 aagggtgttt gtaaatgtag atgaaatact tgaacagaca aaaaaatata ttgaagatag
    28441 aaagccacag gtaaccatat ttgaaggggc agctacatca gacccagttc cagtagagcc
    28501 atatactaat tctttgaaga aaacaataga gttttttgga agagaggaaa aaggaagatt
    28561 tagatttgtt actaaataca gtgatgtgga tagcttattg gatgctgaac ataataatca
    28621 tacagaaata cgatttagta tcaatactcc tagaattata aatgaacatg agcattatac
    28681 agcctctgca aataaaagaa tagagtcagc tgtaaaactt gctagggctg gttatcagat
    28741 tggtttcata atagcacctg tgtttttata tgaaggttgg aaagaagagt ataaaaatct
    28801 gattataagt ataaaagaag ctttaccaaa ggattttgat aaaaaaatta tatttgaagt
    28861 tatatctcat agatatacaa ctaaagcaaa aaatagaata ctagagattt atccagatac
    28921 actattgcca atggaaaatg aagatagaaa gtttaaatac ggtcaatttg gatatggtaa
    28981 gtacgtgtat gataaagaac aattagatga tatgaaagag ttctttctta aggaaataaa
    29041 tggagtattt aaaaatagtt taataaaata tataatatag caaatcttac ctaaagattt
    29101 gctatatttt atttttatat attttatgtt tataataaag caatgagatt tagcattatc
    29161 atataagaaa attaaaaagg gcactatcta tcaagaacat tttttctagt tttgatacta
    29221 taaaggataa gagtaacaaa aatatcagga ggagttatag tatgcatgca tgggagtcta
    29281 ttcaaattac attggattta atagaagcaa atttatcaga agaaatatca attaatgaat
    29341 tagcaaataa agcaaattta tcaccatttt actatcaaag actatttaaa agattggtaa
    29401 ataagactgt aatggagtat ataaagcttc gtcgtcttgc aagagcttct gaatacttag
    29461 cagaacataa gaatcgtata cttgatgtag ctttaaattt tggatttgct agtcatgaga
    29521 catttacacg ttcctttaaa aaagcatatg gattaactcc agaaaaatat agagcaaatc
    29581 cagtaaaact caatcatttt attaagccag aattaatttt aaattatgct atggttgatg
    29641 aaggtgttcc actgattgca gatgatatag tgattgaagt caatcgtaag acattgagta
    29701 atccaaggac atttgttgga atagaaatag aagtacctat ttgccagttg gtgggcggtg
    29761 aaacaactgg aattgcaata gtagaggaat tatggatgaa acttggaagt caaagacata
    29821 atataccaaa tcaaattcca ggtggaaatg aatttgctgc tctttatatg ggaaatgcaa
    29881 aagaaggaaa ttgtatgtat atggcaggtg tagaggtaga gtcaggtaca tcagtagaag
    29941 gatatagtac ttttgagttg ccagctaaag aatatttagt atgtggattt gaggcagaaa
    30001 actttaatga gttagttaat tcagctgttt ttaaagcaga taaatttatg gaaagatgga
    30061 tgaagaaaca taatttaaca actactgatt ttgcaattga gatgtattac cccactacac
    30121 ctgaagcagc atatctggaa cattggattg ttccggttcc tattgaacaa tagaaaggat
    30181 gatgaatatg aattggcaag atgcgttttt tcaagatact aaacctacat ttgagcaaat
    30241 taatgaattt attaataatc cattatggga caagttaaat aaaactttgg tttctactta
    30301 taatgtagaa cctaagcttg aatacagtaa atgttcaatg caaagaggtt ggaatgtaaa
    30361 atataaaaaa agaggtaaat cactatgtac tttatatcca caagaaggtt attttaaagc
    30421 tttggttatt gtaagtgaaa gcaatagagt agaggttgat ttatttatta atacttgttg
    30481 tgattatatc aaaaaaatat ataatgaggt aaactttttt aatggaagta aatggctaat
    30541 gattcaagta gatagtttat tggtattaaa cgatatgctt gaactaatta aatttagagc
    30601 ttaacatata gaacaggatg aatatataag tcatcctgtt tttatattca atcagataaa
    30661 ttaatatata gtctataata tgaataattt agtaaattta aatttacttt atctttctac
    30721 attctttgca actaagtcca catgtgtttt tttcttgcat attagtagca ccccaattag
    30781 caaattgttg taaaataggc acaatacttt tacctttact tgttaatgta tattcaactt
    30841 ttggaggaat ttcattatat tgtttacgat gaacaatacc agtagactct aaatctttta
    30901 atgattgagc tagcatagta tttgtaatgc catccaattt tctttttatg ctactatatc
    30961 taattggatt ttcaactgct aacatacata taataggtaa tttccactta ccaccgacaa
    31021 tgtctaatgc ataacggatt ggacaggtta attcttcaac gtttttagtt atattttttt
    31081 cagtatttat actcatttta attactcctt agttatagta gtatcttttt tatactttat
    31141 cagaaaaaac tgcatacttg ttttttctgt attttatatt aaaattatat caaaggataa
    31201 tccttaatac aagtatttaa aaggggtgta agaattatga aagcattaga atttttgaac
    31261 aaggcaggag tttattattt agcaacagtt gatgagaaca atcaagcaca tgtgcgtcct
    31321 ttaggatttg ttatggaata caatggtaaa cttacatttt gcacatctaa tcaaaaggat
    31381 atgtttaagc aacttatttt taatccaaag gttgaacttt gttgtataga ccaaaacctt
    31441 aatactctac gtattttagg tgaagcagta tttgttacat caaaagaaac acaagctaag
    31501 gcacttgaaa taatgccaag tttaggtcag atgtactctg tgggagatgg taagtttgaa
    31561 atattctcta ttgataaggc aaaagttagt tgttgttcaa tgagtggtaa aaagattgat
    31621 gtagagcttt aattataatt gaatcgacat ccatagtgaa aattaagaaa acgttattac
    31681 tgaaatattg atagatttaa tttaaatgca ataaaaagat ttttaaataa tgaatatgta
    31741 aaaattttta gttattagat gtgtatttca ataatgatat actattttga ataattacat
    31801 actagaaata agataattaa aatttacttt ataatgggat agatttcttt taaaaaatat
    31861 tttaactata attgattttt atttaatctg aaaaaaatat tatgactata aaaaattgct
    31921 acttattatt tggatatttt tatatataaa taataagtag catgacttta tacattaata
    31981 atgatagaat ataaattaat agataagata tgattttaaa aggagtgata taagatgagt
    32041 aaatatagtt ctttatggga atatgttaag aaaaacaata gtcaatcgtt taaattaact
    32101 tttgaagaaa taaaagatat tgctgggata gagatagacc attcgttttt gaaatataaa
    32161 aaggaattaa atgaatatgg atatcaagta ggaaaaatct ctttaaaaga gaagactgtt
    32221 attttcgata aaattggtta agacataaat aattacatat aataaaataa tttgtattga
    32281 tgattactac aaataaaaaa aggcgtagca ctatttttta gtgtcacagc cccttttttg
    32341 tttataatta tgtacatttc acattatcac gatataagca tttttcttat gagaaaatta
    32401 attagaatta tttttattca tatttaaatt atttaaattg ttttcccagt tttttatctc
    32461 ctttttaact tcttcactta aagtatcact tgaagatatt ttctttaatt tatcattcaa
    32521 agatttcttt tgttcctctg aaaggtctgt ttttattgta ggatcaataa tatctattac
    32581 atcttttaca tcaaaatcaa caaatttgca cagttcttct agatgatcaa ttagaaaatc
    32641 tagaccttca tatgaccatt ctttataatc ttttccgttt tttaatagaa actcattcac
    32701 ttggtaattc tgatttgcta attcaaagaa tgaacctgaa ggatccatta tatcatttat
    32761 agagttttca tagttaacaa tattaatttg tcttattaat ttctcttttt ctgttaagtt
    32821 gctataattc ttgttaacaa aagctactaa tccaaattca aagtttaaaa ttgaatcttt
    32881 acgttttttt actgaatctt ctccaaattc cctaagacct tctaaatttt tatcaatggc
    32941 tttatctcta atctctatta attgttctat acttaaacct tctaagtttt taggtactat
    33001 ttcttcatta ttcttagtaa cttctttcaa tttattgtta gtatttttat tattgaaaat
    33061 aaatatagca gttaataaac ttaaaattat tactaaaata attaaactta catttttttt
    33121 acttaacata ttaaacctcc ttttttaaat aagtattgta cttgtgaaaa ataaatttgt
    33181 ttatgaagat aacatttact actgtttgtt ctaaagatta
//
LOCUS       DAEQAF010000040        33047 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.041, whole genome shotgun sequence.
ACCESSION   DAEQAF010000040 DAEQAF010000000
VERSION     DAEQAF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33047
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.041"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            373..1194
                     /gene="yidA"
                     /locus_tag="KRN00_001938"
     CDS             373..1194
                     /gene="yidA"
                     /locus_tag="KRN00_001938"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBH1827804.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMTLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYIQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            complement(1331..1480)
                     /locus_tag="KRN00_001939"
     CDS             complement(1331..1480)
                     /locus_tag="KRN00_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827805.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(1487..1972)
                     /locus_tag="KRN00_001940"
     CDS             complement(1487..1972)
                     /locus_tag="KRN00_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827806.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYVSKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            complement(1985..2737)
                     /locus_tag="KRN00_001941"
     CDS             complement(1985..2737)
                     /locus_tag="KRN00_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827807.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            complement(2737..2874)
                     /locus_tag="KRN00_001942"
     CDS             complement(2737..2874)
                     /locus_tag="KRN00_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1827808.1"
                     /translation="MVQAQTLMHTDVLIGLMIFAALIGFIIDRVLKFINKILCRWRFA
                     D"
     gene            complement(2914..3543)
                     /locus_tag="KRN00_001943"
     CDS             complement(2914..3543)
                     /locus_tag="KRN00_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1827809.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            complement(3504..4067)
                     /locus_tag="KRN00_001944"
     CDS             complement(3504..4067)
                     /locus_tag="KRN00_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827810.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVSKEFKKSKAYSDFITLYNKSVDALKNKATFKKALK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            complement(4077..4301)
                     /locus_tag="KRN00_001945"
     CDS             complement(4077..4301)
                     /locus_tag="KRN00_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827811.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            complement(4306..5397)
                     /locus_tag="KRN00_001946"
     CDS             complement(4306..5397)
                     /locus_tag="KRN00_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1827812.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            complement(5432..5890)
                     /locus_tag="KRN00_001947"
     CDS             complement(5432..5890)
                     /locus_tag="KRN00_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827813.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            complement(5883..6968)
                     /locus_tag="KRN00_001948"
     CDS             complement(5883..6968)
                     /locus_tag="KRN00_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH1827814.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQKYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            complement(6995..7180)
                     /locus_tag="KRN00_001949"
     CDS             complement(6995..7180)
                     /locus_tag="KRN00_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827815.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            complement(7342..7674)
                     /locus_tag="KRN00_001950"
     CDS             complement(7342..7674)
                     /locus_tag="KRN00_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBH1827816.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            complement(7930..8766)
                     /gene="nadC"
                     /locus_tag="KRN00_001951"
     CDS             complement(7930..8766)
                     /gene="nadC"
                     /locus_tag="KRN00_001951"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBH1827817.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            complement(8747..10048)
                     /locus_tag="KRN00_001952"
     CDS             complement(8747..10048)
                     /locus_tag="KRN00_001952"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBH1827818.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            complement(10061..10975)
                     /gene="nadA"
                     /locus_tag="KRN00_001953"
     CDS             complement(10061..10975)
                     /gene="nadA"
                     /locus_tag="KRN00_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBH1827819.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            11393..12850
                     /locus_tag="KRN00_001954"
     CDS             11393..12850
                     /locus_tag="KRN00_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBH1827820.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            13073..13501
                     /locus_tag="KRN00_001955"
     CDS             13073..13501
                     /locus_tag="KRN00_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827821.1"
                     /translation="MNNKLHELEKNLPEISCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            13561..13869
                     /locus_tag="KRN00_001956"
     CDS             13561..13869
                     /locus_tag="KRN00_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBH1827822.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(14016..15038)
                     /locus_tag="KRN00_001957"
     CDS             complement(14016..15038)
                     /locus_tag="KRN00_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1827823.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(15213..15719)
                     /locus_tag="KRN00_001958"
     CDS             complement(15213..15719)
                     /locus_tag="KRN00_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBH1827824.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            complement(15779..16480)
                     /locus_tag="KRN00_001959"
     CDS             complement(15779..16480)
                     /locus_tag="KRN00_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827825.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            complement(16698..17768)
                     /gene="buk"
                     /locus_tag="KRN00_001960"
     CDS             complement(16698..17768)
                     /gene="buk"
                     /locus_tag="KRN00_001960"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1827826.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQYSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            complement(17821..18396)
                     /locus_tag="KRN00_001961"
     CDS             complement(17821..18396)
                     /locus_tag="KRN00_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBH1827827.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            complement(18398..20185)
                     /gene="iorA"
                     /locus_tag="KRN00_001962"
     CDS             complement(18398..20185)
                     /gene="iorA"
                     /locus_tag="KRN00_001962"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBH1827828.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVDHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            complement(20246..21505)
                     /locus_tag="KRN00_001963"
     CDS             complement(20246..21505)
                     /locus_tag="KRN00_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1827829.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLVLVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            complement(21767..23767)
                     /locus_tag="KRN00_001964"
     CDS             complement(21767..23767)
                     /locus_tag="KRN00_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1827830.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEIVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            complement(23775..25661)
                     /locus_tag="KRN00_001965"
     CDS             complement(23775..25661)
                     /locus_tag="KRN00_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1827831.1"
                     /translation="MKRSLIEDLKRNINKIEYDMLTKFYLNLTDLNYILDYHKDLLNT
                     KLEDNSRVYTLYLISLINYIKKDREASYNYLIESLKYIKKLSLKDDSDIISKIYIYLT
                     LSAISIRKYDKVNNFYFSAKKIIRQNHLNELLVLLNMSLCVEISALYQTKTDVIALVE
                     EVSFFKTLKNKALVSRANYIFGRVYLYLFNNFIKSMEYLIECLKLAQENNLYSIEAFC
                     KCIISLCYLESGNNVEAIKYINNVLDVAHSNNSISVTERVSIKIDLIWAYLKEDMNKE
                     AEVILLKTIKLMKVVEGVYKDYLYSFIFLYSAEIELKKDNCSFEKVNTYLILSKNIYK
                     SFGDVFIYNSKLDYIYKLYGDLYIKFGNIDEGISCYIKGLNLVKKSSLNLRKISIFYG
                     LIANGYELKKDFKLAIEYYKSMDWYSDRWEKNNSYKTSQAIHKQYELRQKQESLRLLV
                     DDNKKLENDILKDGLTKLYNRRYLEQQLDLFNETRDKNMVAILVDIDCFKSYNDNYGH
                     LAGDKVIVKVTDIIRSVFIDITEHIIRYGGEEILILVDSIESIGVEEIDNIELYIKRV
                     FKLLEFEGIEHIYSKIKNYITISAGVSIKRCRSRKDVEILIEDADKNLYKSKKAGRNQ
                     YIII"
     gene            complement(25688..27529)
                     /locus_tag="KRN00_001966"
     CDS             complement(25688..27529)
                     /locus_tag="KRN00_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1827832.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPEDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKSFEQSICYLDRAKNILN
                     MIKNIEEYIIYDLEIIYHQAKIYYIFGYYDNALNTNKKLLEKSKNAKNYNYVKLAYKS
                     IYLCFEKIQNYEMSMKYFKMYYELKMMYIKARNRNYIDSLNYRHEYIEKEINNMRKVK
                     LDLDKKKYVDHLTSAYNRTFLNDFLEKQEVSEYCTAFMIDVDYFKEYNDTYGHYNGDI
                     ALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFGRKLCRIVKKFLNNNL
                     TVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHDFKNF"
     gene            complement(27660..28079)
                     /locus_tag="KRN00_001967"
     CDS             complement(27660..28079)
                     /locus_tag="KRN00_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBH1827833.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            28392..28574
                     /locus_tag="KRN00_001968"
     CDS             28392..28574
                     /locus_tag="KRN00_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827834.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            28903..29919
                     /locus_tag="KRN00_001969"
     CDS             28903..29919
                     /locus_tag="KRN00_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1827835.1"
                     /translation="MDYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPDIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWN"
     gene            complement(30714..31307)
                     /locus_tag="KRN00_001970"
     CDS             complement(30714..31307)
                     /locus_tag="KRN00_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBH1827836.1"
                     /translation="MLKKIKKVLSIACCLFILGGSISFADLENNNEINDKSVENPIYE
                     FNIQGYTFTYENAPQRIKDEYNKTCRELNITPSPSTEIFIPIDEISKYTDTVPLFEID
                     EFNVKYFGTRFEVTGAKTYTVGVSTYVGYGHTTSGNPVHLAQLLLKKSGYSIAIDSLF
                     GSSTYSKVRSFQSKYGLSVDGVVGLGTWNKLAQVTNA"
     gene            complement(31369..32391)
                     /locus_tag="KRN00_001971"
     CDS             complement(31369..32391)
                     /locus_tag="KRN00_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1827837.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYSYSKSELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNRVNLDCELCCDESVIYNCSFNDKKEYALALIKSIKLSKECNRGILLTDFNRTNLE
                     KRLESIISKKFKNSVFVVIILCLLSSITYFKFDIFISKPVIYSLPKPSVLNDEYIYNT
                     DIRVER"
     gene            complement(32384..32761)
                     /locus_tag="KRN00_001972"
     CDS             complement(32384..32761)
                     /locus_tag="KRN00_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1827838.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
BASE COUNT        10985 a         5583 c         3529 g        12950 t
ORIGIN      
        1 tgaataataa catatgatta atggaattac aatattttat aacacaaaac taactaatat
       61 aacaaattac catcagtcta tttattcaaa cttctaacta tataatatgc atttatttat
      121 attaacaatg caaacgatac cattatttgt aattaagaat tttggaatta ttgattacaa
      181 agtttttaca ttctcatctc acataagtaa tatttttatc aaaaaattaa tattattaaa
      241 ctttctaaat tacttatctc ttgatataat agtatacaaa acaaaccata tttcccactg
      301 aaactttgtt caacactagc tgtgtcaacg ttttcacagg aaatttgagt atataattta
      361 ttggaggttg atatgtacaa attaatcgca ctagacattg atggaacaat attaaataca
      421 caaaaaagga ttactcctga agtctttgag tccattcaag aggcaaaaag ggctggggca
      481 aaagtagtta taacaacagg cagacctctt cctggtgtaa aagaacttct aaatcaacta
      541 aatttaacag atgaaggtga ttatgttata tgctttaatg gagcaattat tcaagaagtt
      601 aaaagtgaga aaatcataca tgatgtagaa atgactttag atgattttga ttttatatat
      661 aataacgttt gtaaaaaata taaaactaaa atacacataa atacaatgac aaatttaatt
      721 acaccaaatg aaacgcctgg caaatataca cttcatgaag cgaaattaaa taatatagaa
      781 gtcaaatata tacaaaaaga taaaattgat gaatctatta aaatctgtaa aattatgata
      841 gttgatgaac cagaaagatt ggaagaaatc atacagcaac tacctaaaaa tttattcaat
      901 aaatatacta tagtaaggtc tgcccctttt tatctagaat ttttaggtaa aactactaat
      961 aaaggaactg ctcttaaaac attatgtacg aatctaaata tacctataga aaatgctatt
     1021 gctgttggcg atgaagaaaa tgaccaacat atgataaagt atgcaggtct tggtgtggct
     1081 atggggaatg cacgtaatag tataaaggaa attgcagatt acgttactga tactaataat
     1141 gaaaatggag ttgcaaaggt tataaataaa tatatactta ataaggctat ctaatcatct
     1201 aaaaaaaact aaaaatatac ctttagattt aaatactttt cacatcccta ctctatacta
     1261 atttatatag tatggatatt acctatcatt tttatctaaa ggtcattttt agtttttcat
     1321 atatgtatat ctatgatagt accttttgtt tgagtttaaa tattttatat gattctacta
     1381 ttgcctcatt aatatctaaa caatatatat cttcatcatc agataatcct gcttcgtttg
     1441 tccaagcatc aaaatcactc ttcgtccaga agaaattcat tatatttcag caactagcag
     1501 cccaatttag atgcttatca agatttatat gaagcactct taagtttgga ttattcacat
     1561 actcaatctt ttcatttttt ataattactt ctatttcctt acctgtagca ctacaaatag
     1621 agtttatttt tatatcttgg ttgaatgtgc aagaggttcc tatagcatct atagcacaca
     1681 ttgcactgaa acttctatta tctctcaaag ttactttatg atttgttggc aatgctgata
     1741 caggatatat aaaatttata ctattcccat caacaaccat tatattttta taaataaaat
     1801 attgtagtgt cctttctata tattcttttt ctatattcaa ctttttactt acatattcag
     1861 tcacttcttg aagtgtaaca ctagaacctt tatctattat catatccata atagagattc
     1921 ttattttctg ttgtgtatta tccaaactat tgtatttttc tatttgactc atgtctactc
     1981 ctctttaaac ttcataacac tttgataaag tatcagttaa tttgtttttg tactcttcat
     2041 atttttggct tcctctaatt ctaggtcttg gaatatctat atttatatca tcaataattc
     2101 ttcctttatc tctcgacatt actataactc tatcactcat atatacagct tcatcaacat
     2161 catgagttac cattaatgca gttattttct tctttatcca tattcgttct agctcttcct
     2221 gtaaattttg tctcatttga aaatctacag ctcctaatgg ttcatccatt agtaatacct
     2281 ctggattaca tgctaaagct cttatcatgg ccactctttg tttcattcct ccagataatt
     2341 gatgcggaaa cagtttttct tttcctttca agtctgacat aaccaaaagt tcttctagca
     2401 tttcttctct tttttctttt ggtattttct gctgtttcat aggaaataga acattacctc
     2461 ttatagtttt ccaaggaaat aaagcataat tttgaaatat aaaagctcta tctatgcccg
     2521 gttttttaac tcttttatca tttataaaaa catctccacg ttctgatttt tgaaacccac
     2581 ctattatagt aagtaaagtt gtttttccac aacctgatgg tcctaaaaga cagacaaatt
     2641 gtccatcatc tatatccata cttatatctt ctaaaacctt tgtatgtact ctattattta
     2701 caaatgtctt atttatatct cttacactta acttcattaa tctgcaaacc tccatctaca
     2761 aaggatttta tttataaact ttaataccct atctattata aatcctatta aagctgcaaa
     2821 tatcataagc ccaattaata catctgtatg cattaatgtt tgagcttgta ccattgagta
     2881 accgagaccg gcactcgtag ctataaactc ggctcagata acagacatcc atcctgtact
     2941 tatagcaatc cttgaaccag ttagtatatc tggaagagat gcgggaacaa ttacatttgt
     3001 aaatatcaca attggcgatg ctcccatact tctagctgca ttataataat cctttgatat
     3061 tgctcttact ccttgaatag tatttaaaat tatagggaaa acccctgaaa aagctattaa
     3121 aaatattgtt ggaccatctc ctataccaaa ccatactata gtaagaggaa cccatgccat
     3181 tattggaact tgccttacag aatctactac tggagataaa accctttcaa aagttttaga
     3241 aaatcccata ataaatccta ttggaagccc aaacaataat gcatacataa aacctttaag
     3301 tactctctgc aatgttataa aaagattagt gactgtctct gcatctgtca cacagaaaaa
     3361 gaaacctttt attacatcta ctggcattgg aagtaacaaa gaactcccta tatcttttgc
     3421 tgcaaaatgc cagactaaaa atataataac taatagtatt attttatata aaatatccat
     3481 actaccatca gtttttttct tagttaatct atcgctttta tctttagaaa ttttaatttc
     3541 caattgctta tttcctccat atctatattt cttatattcc tgtactcttt taatgctttc
     3601 ttaaatgtag ctttattctt taaagcatca acacttttat tgtaaagtgt tataaaatca
     3661 ctatatgctt tacttttttt aaactcttta cttacaacta atacataggt atcataatct
     3721 cctaatttag ttgtagattt tcttttgccc tctaacccaa ttgactttat gcaatctatt
     3781 acaacaccat ctactaaatt actttctaat ccatatgcta gtgcagtccc taataaggga
     3841 gctacttcca cattcttgta gtatttttta accaattctg actggtaatc tctattttga
     3901 atgactccta tcttttcagg attattatca cttaatagaa atatatcaga attttgaact
     3961 acagtaccaa caatttcaaa tccactattt acatttacat attgttttgc agcatcttta
     4021 catatgattg ctatatctat ttcctctgaa ctcagagccc actgcattgt acttgctcag
     4081 caatcattaa ttgtaaaaat atccattata tcacttactt ttatattttc aaagtagtct
     4141 ctatttacca tataatttat tacaaaacca gaggtatcat cagatacccc tattcttaat
     4201 tttcctttta tttcttcttt atcttcaaaa ttaaaaaata ttataaatat acttcccaaa
     4261 ataatgataa aaagtattat tatatttttc atattctcca tttatttata atacctttgc
     4321 tttccagtct tcataactca taccttcagg aaactctggg ttaacttttt cttttataaa
     4381 tttgtcaaaa tcatcagctc cacaagagtc caataagctt gtatcaatcg tatcttcata
     4441 tttaggtata tcatctaaag cctttaaatc tttatacatt tgtaaattat ttttatattc
     4501 ttcacctgta actttccaag taagagttct accttctcca acagtcttct tatagatagt
     4561 tctaagtgca acttcttctt ctacattata atattttgca aatattttag ctgcttcagc
     4621 tggatttgta tatatatatt ctattgcttt tgtatgtgct agaaccaatt tttttgctaa
     4681 atctggatgt tcttttataa agtttttgtt taatgagaat gaacaacagt tatattcttt
     4741 gccattagct ttttctttat attgagtaga tgctattatt tttcctgcac cgtcattttc
     4801 agctacagaa ccccaagggt cacaagatgt aaaagcttga attttcccag ttttaagagc
     4861 taaatattta tctttgtctg aatccatatt tacaacttca tattttgatg ggtcagttgg
     4921 tagacctgtt tctggaccat aatcacttgt ccataagaaa tcactcatat ctgttgcaat
     4981 ttttttacct attaaatctt taggttcttt tatatctttt gaaactatta aatattcaga
     5041 accaccagta tggttgttag ctgctattgt tattggtgaa cccttaggta ttgctccaac
     5101 taacccctta gttcctatgt aacctgcatc catttttcct gctgccatag cttcaggaac
     5161 tttaccattt ccaacagttt ttacattaag acctaaatct ttatatattc ctgccgattc
     5221 tgctactggt cccgcagtca tatggtcaca attataataa cctactgtta ttgtataatc
     5281 atcttttcca gtttttgctt cttctttttc ttttggttta ctactacatc ctgttaatat
     5341 agatgtaccc attacaccaa ataagattaa tgcttgaatc ttcttagata atttcatata
     5401 aatttcccac ctttatgtat tatttttatt tttagcaaca tttgtccata tcttcgccaa
     5461 ataaatcaac aaatttttta ccctctactc tgtaaatagc atatcctaca ttaccatttt
     5521 tagaccctga tacaattact tctattggtg ctttatcatc aatattttta aaggttatag
     5581 tttgattctc tataggtgct ggtattggct ttgttatata gtggctattt ttatcagaaa
     5641 ctacgactac catttcattt gaattattgc tttttttata tataactact aaatcttttt
     5701 ttccatcatt atttaagtct tcttcagcac aagttattat gtcttcttta taattttttc
     5761 taaaatattc taatgtttct ttattcacat ttggaataga agcatcttct ttgatgttat
     5821 catcaactat ttttgataaa atgattaaca caactactat acaggatatt ataactatct
     5881 ttttaagcat gatttcctat gacctctttc atctttggta ttattgattt aaatgcaaat
     5941 aaaataatta aaatagtaca tacatactca aaactatcag gtatgtttaa cattagttta
     6001 tttgccaact gtattgaaga atttgttgca tctaaattta ctgagttatt attcactaaa
     6061 agtaaatttg ttatatatcc aattattatt gaagacagtg tcaaagttac agaatatata
     6121 ataacagttc tttttccaat aagtttaaac atacttataa gttctggtag atttgtagct
     6181 gctccagcta ttagaaatgt tatcgctata ccaggagatg ctccacttgc aacaagggct
     6241 gctataaacg gtatatgtcc tacagcacat acatacataa cacatgcaag tattgctata
     6301 cttccaagag atagcaaacc tggatttcct aaatattttt gaattatact atttggaaaa
     6361 atagttgtta taaatcctgc aaaaaccata cccattacta catatttact aatagtaagg
     6421 gctaattcac caaaagacca tttaagacca tcaatcatat ttcccataaa acttcttttt
     6481 tcttcttcta attctattac ttcttcctct gaatcattat gaagtgataa ttcttctttt
     6541 ccaaaacaat ttcctaaaaa tcctactaaa aatggtacta aaaaaccagc tattagataa
     6601 atgattgtaa ctttaggacc taaaagacct agacaaagaa ctacagctat tggatttatt
     6661 attggagttg atgtcataaa agcaagtact ggtcctaaat atgctcctga ataatacata
     6721 cttattccaa gtggtattac tccacaacta catattggta aaaacattcc tgagatagta
     6781 cttttaatta aagaagaaaa tttcttattt ccaagttgtt tttgaaacct tcttggagtt
     6841 aaaacattgt gaagtacacc tgccaatata aaacttatca taagccatcc tgatgctcca
     6901 ttcagtgtaa ctatagaagc tactatagta tctttaactc catttaaaac aatttctaat
     6961 atattcattt ttgatactcc taatttttaa acttttaatt attgtttata gcttctacta
     7021 ttgccctttc aattgtatct ttatttaatc tatcatattt ctttttctga tttattatta
     7081 aagttccttt tgttataatc ccatattttt ttatatacga aaaatctttc cctgcttgat
     7141 ataattttat ttccaattta tcagcatact tttctgacat tttttttata aacactccat
     7201 gttcatcaca agatggtcaa gtgtttataa attcaactaa aattttagac atttgttaat
     7261 cccctacttt aaacaattta tcttttactt aaaataatcc acagaaaata aatttttcta
     7321 tggattgtat cctatactaa tttataacgt tataacttgg tccacacctg cactgcctaa
     7381 acaagcatat aggtttggga aacatccaat tgtagctcca tcaaccaaat tattctctat
     7441 acctctttct atagcacatt ggtcacaagc cattattatc atatcagttt tttcatgtaa
     7501 tttacttagt ctctcgccta caggattacc tttagataaa aataaggtat tatccataaa
     7561 gaaaaacatc cctagaacgt ctactccatg agttccttgt tcaagttgtg gtattatcat
     7621 tttgtctaga attttatgtg tattagtact actaaaaata taagctactt tcatttttat
     7681 tccccctata ctttttatat tttacaaaat tttacagata caattatatt ataagtttat
     7741 tcttatttat ctgtaaaata gatattaact atattattaa aagtgtatat agtatttatc
     7801 tatttttatt aaattattga ttgatttttt tctattttta ttaattttaa tgaataaaaa
     7861 atagactcct taaatttata aaacaaattt aaggagtcta ttttaattaa gtttatttca
     7921 atataaaatt tatatatttc tcaaattctt catacttata tcgagagctt taacagaatg
     7981 tgtaagcgct cctacagaaa caacatccac accaattttt cctatatctt ctatagtatc
     8041 taaatttaca tttccggaaa attctacaat ggctcttcca tttataatat ctactgcttg
     8101 ttttgccatt tctaaactca tattatccaa cattattata tctgcattag cttctattgc
     8161 ttcttttacc atgtctaaag tttccacttc cacttctatc tttctaacaa aagaagtatt
     8221 ttttctagct aattcaactg ccttcttaac actaccagca gccccaatat ggttgtcttt
     8281 aagcaatatt ccatcagata aattaaatct atgattgcat cctccaccta ctttaacaga
     8341 atacttatct aatattctaa gattaggtat cgtttttcta ctatctaata attttgtatt
     8401 tgtaccttca agcttttcaa catacctact tgtaatagta gctataccac tcattctctg
     8461 taaataattc aatgctacac gctctcctac aagtaagttt ctagtactac ctgttaatac
     8521 agctatcttt tcacgattct ttactctatc accatcattt ttatataatt ttacatctac
     8581 atcaccaagt atctcaaaaa ctctcttaaa tacacctaag ccagctatta taccatcttg
     8641 tttacaaatt aaatctacag tagatttaga attttcatcc acaatagaat tagttgttat
     8701 atcttcactt ggaacatctt ctatcaaagc atcctgtatc attctatcaa taatcaaata
     8761 attcatcgcc aaaatcctca cttgttcttt caatttcttt tatgactaat attttatttt
     8821 ctttttttac ctgttctata tctatatcca tatctggtac atctataaac ttaactttta
     8881 cattatctat aactgagttt atatttttag ctgctctttt tgaaaataca agcccttcaa
     8941 gtaatgaatt acttgccaat ctattggctc catgaacacc tgtacaacta atttcaccaa
     9001 ctgcatataa attttccata gatgtttttg aatccaaatc tacatgtatc ccgcccataa
     9061 aataatgttg tgcaggagat acctttatac attctttcgt tatgtctgtt cctctagcta
     9121 aacattcatt ataaataaaa gaaaatctat taattaaata ttcactatct aaatgtgttg
     9181 catctaaata cacataaggt aatttatctt tttccatttg ctcaaaaata gcttttgaaa
     9241 ctacatctct aggaagaagt tcatccacaa atctttcttt atttttattt aaaagtttag
     9301 ctccctctcc tcttaatgat tcagatataa gcattctcct accttcatta ttttcttcat
     9361 aaaaagctgt aggatgtatt tgaatatatt ctaaattttc tatttttata ttatttctta
     9421 aagctattgc aattccatca cctgtaagat gtctttgatt agtagaattt ttaaaaagcc
     9481 caccaattcc acctgtagct aaaactacta tttttgaaaa aacatgaatc tcttttttag
     9541 atttaaaaat tctagctcct atacatttat tgccatcttt taatatatct aaaagatatg
     9601 catcttctat aagagttata ttttctctag ttttagcttc ttttaataaa gttttaaaaa
     9661 caacttctcc agtattatcc ttactatgaa ctattcgatt tacactatgt gctccttctc
     9721 ttgtgtaatc tatctctcca ttttctttgt ctaaaggcat accatattct actatctgcc
     9781 ctacattttc tatagattca tctgcaagta cttgaactgc ttcaactcta tttttatact
     9841 gcccagcctt cattgtatct tctacaaagg attctatatc atcaatattt ctagcagttg
     9901 aaattccacc ttgtgcaaga tatgtattgt tgttttcaat tgttgatttc gatactacta
     9961 gcacatttaa acttttatct aaatttaatg cacagtataa tcctgaaact ccacttccaa
    10021 ctattaaaac atcttgttct aaattcataa gtctatccct ctatccttct gctaatttgt
    10081 gcatgttaag cagtgaattt aaagcctttt ccatgatttc atcttctaca ataacttcat
    10141 tttccatatt tttaagtgta ctatataaat tttctaatgt tgtctttttc atatctgtac
    10201 atagtatttt tccaccagga atataaaagt ttttattagg attatttttc tttaattcat
    10261 gtaatatacc ttcttcagtt gctattataa agtctttgtt tttactatta gtagcatatt
    10321 ttattattcc tgatgtacta cctacataat ctcctaaatc tcttatttct tttttacatt
    10381 ctggatgtac taatacttct gcatttttat acttatcttt taactcaatt atttcttcag
    10441 ctcttatatt gttatggtat ttacaatatc cgtcccaaaa tataaagttt ttatctggaa
    10501 attgttctgc aatatatcct cctaaatttt tatctggaag gaatataatt tctttattat
    10561 ctatgttttc tagtatttta attgcactag aagatgtaac agaaacatca caatgtgcct
    10621 taactttagc tgtagagttt atataacata caaccaaagc atttggatac tgttgtttta
    10681 attttatcac gccttcttca tctaccatat ctgccatagc acacccagcg ttacttactg
    10741 gcatcaatac agttttttca ggtgataata tcttagcact ttctcccata aaccttactc
    10801 cacaaaatac aaccacttct tctttacaat ctctagcaat ctcacttaaa taatatgagt
    10861 caccaactgc atctgctaat tcttgtattt ctggtggttg ataaaaatgg gcaagtatta
    10921 ttgcattttt ttctttcttt agctctttga tttgatatgt taaatcttta tccataattg
    10981 caccgctttc tatatgtact agtgtatata cacctgtaaa ctcattatat cacttgacta
    11041 ttctttcttc aagaatttta aacctcttaa tattgttaag atatagacat ttatattctc
    11101 aattgatttt ccttttttct ccatctattt aaactaattt ttatattttt taattttttt
    11161 gtaaaatatt atcagaattt tgtctatatt ctttattgct ataacattga aaatattacc
    11221 aaatacctgt atactaagta catggttatg tatatgtatt tatttctgaa attatattag
    11281 ttgtaatact ttatagaatt tgtaggttgt ccagaattaa attcaatata aatctacaca
    11341 tttagataat atgtatacaa agaccaaaaa attttataaa tggggtgata ttatgacaac
    11401 attcttaatc ggcttggcta tattactaat aggaggtgct ttatacggtg cttattgtga
    11461 aaaagtattt ggcccagatg acagaaaaac acctgcactt gctcaaagtg atggagtaga
    11521 ctatgtccca atgaaaaaat ggaaaaatag tctaattgag ttgcttaata tagctggtac
    11581 aggaccaatt ctaggaccta tccaaggtat attgtttggt ccaatagcat tcatactaat
    11641 acctattggc tgtgtatttg gaggagcttt gcatgactat atgagtggaa tgattagtat
    11701 aagagaaaaa ggagcacaaa tgccttctct tatcagtaga tttttaggta ataaagtatt
    11761 tcaagtctat aatatattcc tttgtctttt aatgctttta gttggtgcag tttttattta
    11821 tacacctggg gatttagttg ttactcaaat tttaaatatg aaatcgacta taaataatcc
    11881 agttgtctgg atagtttatg gacttatctt tctatattac ttgtgtgcaa cactatttcc
    11941 aattgataaa atcataggaa aggtatatcc aatatttgga gctattctac ttttatctgc
    12001 tgctggtgtt ggaattggaa tctttacaca aggttatgat ttagctaatt taagtcttgc
    12061 aaattggaaa ggtattcatc ctgatggtat tcctcttatt cctacattct ttgttacagt
    12121 tgcttgtggt attgtttctg gattccactc aactcaagct actcttatag caagatcagt
    12181 ttcaaatgaa aaagaaggaa aaactacttt ttataatatg atgattttag aaggtttaat
    12241 tgcaatgatt tgggctgcag ctgctatggg tatttacaat aaaggaatac ctaaggaatt
    12301 agtaggttct cctgatgtaa taggtttggt tgcaagagat ttacttggtt ctattggtgg
    12361 tatcatagct ataataggtg taattgtttt accaataact tctggagata cagctttaag
    12421 atctttaaga ttaatgcttg cagattactt tcattatgac caaaaggaaa agaaacatcg
    12481 tgttatattg tcaatctgta tatttattcc tgtcatagcc atccttatat ttgcaaagct
    12541 tagtgcttct ggatttaata tattgtggag atacttctct tggagtaatc aaactattgc
    12601 catatttgca tttgcaatga ttacagttta ccttataata aaagaaaaga attatattat
    12661 aagcttaatt cctggtatgt tttattcctt tgttatattc agttatatat ttaatgctca
    12721 aattggattt aacttaaaca taaatatatc atatgtttta gctgccatat ttactgtatt
    12781 atatgctatt ttaactgtac gctctggtag aaagttaaaa agcaaagcag atactaagtt
    12841 ggctgactaa atctaaataa aataatactt agaataaatt ttattaaaaa atgataaaaa
    12901 agtaggcaat ctcaagttag atttgcctct tttttattta atacagtaat aaatacttaa
    12961 gtatttactc cttattggaa tatttatcct aaatctctaa tataaataaa taaaagtttt
    13021 aaaataatct attcatttat atacttaaaa taaatttttt ggaggaatac ttatgaataa
    13081 taaattacat gaacttgaaa aaaatctacc agaaatatct tgttcttttt gcacacatct
    13141 ttcatttaag gggcctagcc tagactatag atatgatatt agatgtgtta tttcagatac
    13201 aaagcccgat tttagaggat gttgtgaata ttttgaacca gaatatacag aattaaatac
    13261 aggagattta gacaatctat acataaactt tcttgagaca tgcctcaagg taaattataa
    13321 tgattacatc aattctatgt attggaagtt atttaaagaa agaaccctac tagaaaacaa
    13381 ttttaaatgt tctatatgtg gatcaactga aaatgttgat gtgtatcatg ttaataaaaa
    13441 tttaggaagg gaaacttcca aagatgtagt tgttaaatgt gataaatgta attgtaaata
    13501 agtgtataaa atttagataa cttcacataa taagtttaaa taaaacttag gaggttattt
    13561 atgaaaaata ataatttaaa ttgtgctgct actaattgtg cttataatac tagtggatat
    13621 tgttatgctg gtagtataaa agtagatgga atgcaagcaa ctactacaga aaatacttat
    13681 tgtgcttctt ttgaagacaa atatacatct ggtataacta gtcgttctaa tgaaactaac
    13741 caagttgata cagataacat tcattgtgaa gctgtaaaat gtaaatacaa taaaaatgaa
    13801 ctttgcaaag ctgaaaaagt tcatataaat gaaagaaatg caagttgtga aacttttgaa
    13861 atgaaataaa tttcttttta tttagtttta tagtatttat acaaagcaaa attgaaccta
    13921 tcaaatagat gtctttatta atgatgtcta tttataggtt cttttttaaa acaattcata
    13981 atttatatat aaaaataaat tattatttta atatattacc tagaagtaaa tttaacaccc
    14041 agaatatcca taaggaacat aaatattgga actccaatta gtaatcccca tacacctaaa
    14101 taatgctctc ctacaagtaa aataataaaa acaaaacaaa ctggaagttt agttctattc
    14161 gacatcaact tagggtttaa tatgtatgtt tctactgcat gcactataca aatcataagt
    14221 aaaactccaa aaacctttgt tattcctcct gtattaaatg ctattacagt taatggaatc
    14281 aaagacacta taactcctgc tactggaata agacccaaca caaaaatcat aaatcctaaa
    14341 gcccatattt gagggaatcc catgaaacct aagaaaatca tagaaacaac agaatttata
    14401 aaggcaatca taacttgtac tttcattact tcaccaaaat ttttaacaaa gctctttcca
    14461 aaaaatacaa gcgaattata aataaaagaa atcttactat cagaaagttt atctccaaaa
    14521 tttttaattt catttttttc aagtaaaagg agtaaactca gtaaaaatgc caataatata
    14581 tttactccaa aacttccaac ttttgttgct gttgatgcta taagtagccc tgcttgtgaa
    14641 atatatttat taaaatccag ctttgagaca ataggataca atttcggtcc taaagattga
    14701 gcaaattgat ttacatcaaa atcactaaaa accctactca actctgtaag ttgaactata
    14761 attattggta caactgcata gctaatcaat actaacaata tagcaaatag tgcatataac
    14821 actataatta ttaatgaatc tggaatattt aaagaagaaa acttcttaat tcgttttctt
    14881 gtggctacaa gcaagttata gaaaataaaa gtcataataa atgttaaaag caccatattt
    14941 aacatatacc aaaatgtaat tagaataatt actacgacag atatagaaac aattttatat
    15001 tttgaactgt cacgtgccaa tcctttgtta tcttccatag tttaaatcct ccccaaattt
    15061 ttatgacttt ataatgactg ccctttttat tttaatctca aaaaacaagt agaaaaatac
    15121 taaaaataac ttattaattt tcataaaaca atattaaaat ttagagaaga tacattttaa
    15181 ataatcttac ttatactgaa atctgctcta catcatatat ttaatttatt attatctatc
    15241 tcatatagca attcgtatat ctctggatat tcaaaaaaca aaccctcttt tagtaattgt
    15301 cttatttcat ctgtgcttac ccactttata tcacttactt cttcctcctg taaaatagct
    15361 ttagatatat catattcttt tttaactaag tatacatccc aaagagtatc ttcatgaatc
    15421 atacttctaa aaactttcat ctcatcttta gttatatcta tccctatttc ttcctttgct
    15481 tcgcgaattg ctccttctaa actgtcttcc ccagaaacaa tacatccagt tgtcattccc
    15541 cacatatttg gcaatgtttt tttactttta gaccttttct gaattaaaat ttgagagtta
    15601 ctatttaaaa tccacacttc aactgccaaa tggtaataac cttcttcaat agaattacct
    15661 ctttttataa catttcctgt tttaattcca tcagcattat ataaatccca taattccatt
    15721 tcaaaatctc cttgacttta ctataaatta gataaactac aaatatattt tagcataatt
    15781 aattctgctc attttttatt acaatacttg atttacattt atgttcattg cttttctttt
    15841 ccttccattc tcttatatca tctataataa atctatgttt cagcaatttt gtgtcaaatt
    15901 taaatattct aaacactatt tgtaatacat atcctaaacc taaagcactt acaagcgtac
    15961 caatacctac agaacctcct aataaccatc caacaactaa tgctagtatt tcaagaattg
    16021 ttctaacaag acgtacagat ttattagttt ttttctgaag agcaatcata agcccatctc
    16081 tcggtccact tcctaaacaa acacctaagt atagaaaact tgctatagct gccaaaataa
    16141 ttcctataac aaccataaac acacctatat aagtgttgct tgcatgaggt atcactccag
    16201 aaaatattac taaatcaata aaaattccta taaatgtcat gttgagtaaa gtaccccatc
    16261 ctatattttc accaaaaact gcatccaata taacaattac aactcctacc attatagaag
    16321 cctgacctat agttatgcct agctttatag ataaaccttg gtgaagtaca tcccaaggca
    16381 taagacctac atgtgcatta atcataagca cagaagaaat tgcaaatata aaaaaacctg
    16441 aaaataatct tatcatactt tttaaactta tttttcccat caaaaatcac tcctcataat
    16501 aataataaca ataaatacca ataaaatata tatataaata cgaaatttta cagaattatt
    16561 tattaggtta agataaaatt ttaattataa aaagtggcaa tccaaatttt atacattttc
    16621 acctatactc taagctttcg tgtataaaaa acggatatac cactttttta gtatataaac
    16681 atttttagtt tttcttatta attttcacta taaattctag cttcttcttc tccatttagt
    16741 actcttaaag ttccaaaagc aagtgattcc aactcatttt ctcctgccat aatttctact
    16801 ggtgctataa actcaacttt ctttttaacc attgaagtaa acatttcaga atatgcaatt
    16861 ccacctgtta taattatagc atctaccttt ccatctacta cagttgctaa ctctccaata
    16921 ccttttgcta actgataagc cattgcttca taaataattt ttgcttcttc atttccttct
    16981 gctatcattt tttcaacttc tctagcatct acagtattta ggtatgaaac tataccacct
    17041 ttacctctta tctttttagt catttctctt tctgaatatt gacctgaata acaggcagcc
    17101 actaattttg tagcaggtac tcttcctgac ctttctggag aaaatggtcc ttcatcatca
    17161 gatagcatat caaccattct tcctttttca tgaagataaa tacttactcc tccaccaatg
    17221 tgagctacta ttaagtttaa gctcttataa tcttttcctt tatccttagc atattttaaa
    17281 gccattgctc tagtatttaa tgcatgccct gcacttgatc tatccattcc acaaagtcca
    17341 gatattctcg ctacatctat aagctcatct actgcaacag aatcataaat atatgagttg
    17401 attccaagag gttctgatat tgcatgtgcc acaacagcac ctaaattgga agcgtgttca
    17461 agtactggtc tatgtcttag tacatcaatc atttcttcat ttactaaata tgctcctgat
    17521 tttactggtg gtaaaactcc acctcttcct actattgcac taagagattt taagtctata
    17581 ctattttctt taagaatatt caaaactgct tccttacgca tttcaaactg gtcttgtata
    17641 gtattatatt ttgcaatctc ttcagctgga tggtctatcg tcttcacaag aatttgttct
    17701 tctccatcat atactgctat ttttgtagaa gtagaacctg gatttatggc taatattctg
    17761 taagtcataa ttttcttcct ttcaccttaa tttctatagt ctatttatat ctattataaa
    17821 ctatttgcta accatttcca taccttcatg gaaagctttt atgtttaatt caacaaattt
    17881 tggtttaaca ttttcactta taattttttc ccaatcaata gactctaatt gcatagattt
    17941 aactagacat cctaataaaa taacattcat tatttttgaa tttcctagtt cttcagcttt
    18001 atcagctgca tttataactt ttgcatttaa tctacttaac tctgcatcta tatcactttc
    18061 ttgatattca gctcctccga ttaaaacagt catagaatct atcctatgat tatttactaa
    18121 agcttttcct tctggtttta aataattgaa ccatcttaaa gcttccattt tttcaaaaga
    18181 tactaatata tctgctccac caatttctat aactggagaa tgaacacaat ctccatatct
    18241 aacttgtgag gaaactgaac ctcctctttg actcattcca tgtatttcac tcatctttac
    18301 atcatatcca gcttccatca atcccatagt taataattta ctagcaagta tagttccttg
    18361 acctcctaca cctaccaaaa gtatactctt agtcatatta tttttcctcc ttaactattg
    18421 cttgttttgg acaaacttgt gcacatactc cacatcctac acactgattt ctatctatat
    18481 ttgataactt attctcttta tcaaatgata gagctggaca tccagttttc aaacataatt
    18541 tacatcctat acatttatca tggtcaactt tacacttagt cttaaatgga ttattaaatt
    18601 cttctatatc ttctttagag aattttttaa gtacacatgg ccatcttgtt attattactg
    18661 atggttcatc ttctatagct aaagcccaat ctagtgcttc atttacttct tttaaattat
    18721 tagggtttat aactcttaca tgttctattc cacaagcttt aactaatcct tctatatcaa
    18781 cttctttagt tttagcacct tgtaaagtat atcctgaacc tgggttttct tggtgacctg
    18841 tcattccagt tattctatta tctaatataa ccgaaataga attacctcta ttgtaaacaa
    18901 catctaaaag tccatttatt cctgtatgga agaatgttga gtctccaagt acacctacca
    18961 atcttttttc attatcatcc ttcatattaa gaactttttg agctccatgt gcagttccaa
    19021 aagcagaacc catacaaaca acataatcta ttccattata tggaggagca aatccaagag
    19081 tataacaacc tatatctcca ccaactatta aattttttct ctttccaagt tcatagaaga
    19141 atcctctatg tggacatcct gcacagaaac ttggtggtct tggtgttact aattcagatt
    19201 tgtattctat agtatcattt gtttttccaa atatagcttt tcttaaaaca tctggtgtca
    19261 tttctccata tggtggtatt acatcttttc caatacaatc tattccatat gcttttattt
    19321 gttcttctat aaatgggtca ttttcttcta taacatatat tttatcaact ttttctgcaa
    19381 attcttttat tttttcataa ggtaatggat ttgtaaatcc tagtttcata tatgatgcat
    19441 tttttccaaa aacttctttg gcaaaattac agcacatacc agaggctata acacctattt
    19501 ttgtatcatt tatttcatag tagtttaaat cagtttcatt tgagaatttt ttaagaattt
    19561 ccattctttc ttcaacaacg ccccttctta tttgagcatt tgctggaaca gttaccattt
    19621 tcttagcatt tttaacatac tctttaattt caacttcttc tctatcatag cactccacta
    19681 atccttttga atgacaaagt cttgttgtaa ctctatataa aactggtgta tcgtattttt
    19741 cactaacttc aaaagcttct tttatcatat ctttagcttc ttgactagtt gatggctcaa
    19801 ataaaggtat ctttgcaaat tttgcataca tcctattgtc ttgctcattt tgagatgaat
    19861 gcattcccgg ctcatctgct gtaataagta ccataccacc atttacccct gtatatgcat
    19921 aagtaaatat tggatcagct gcaacattca aaccaacatg tttcatagaa gccattgttc
    19981 ttgctcctgc aattgaaccc cctatagcag cctcaagtgc taccttttcg tttggagccc
    20041 actctgcaac tattgcatct ttatatgttg ctatattttc taatatttct gtacttggag
    20101 tccctggata tgcagatgca tatttaacac cagcctcata ggctccacgt gcaattgctt
    20161 cattacctgt catcaattgt ttcatataaa attccctcca tctacaatta ttaaattcat
    20221 agtccaccca atttgttcaa tgaaattaat tatttatttt tacttctaaa ctttcaagtg
    20281 cttcttttat aatacttggt gctttcttac atttatcttc agaaactgca caaactgcaa
    20341 atcttaaacc catttttaat ggaactgcaa ataaattatg tttagtcaat tcttcacata
    20401 cttcttttgg attatcacat ggtatactta caaagaaacc tgctatatat ggaagaattt
    20461 ctaatcctac tctttcagct tcttttacaa atacatctgc tcttctagta agcatgtttt
    20521 tgtatatttc tttttcatcc tcatattctt tgaatttttt agggtcattt acaatgttag
    20581 ataatactgc catggcactt ctattacaat ttgaccaatt tgctctacat gaatgaacac
    20641 atgagtaatg gaactcttca gctacatctt cacttgaaga tatacaaatt atagccccca
    20701 ttctcatacc ataagctgta aatccttttg acatactgaa tccaaccaat acgagaacgt
    20761 tttcaggcaa attagaaaat ttcttaaaaa actttctaca tacatcatca tcacctgcaa
    20821 agtcaatata tgctgaatct acgaaaaata ttatcttttt gtctttatct tttgcgactt
    20881 cttttgataa gtctaatatt ttatcccact catcatctgc aacactatat ccagttggat
    20941 tatgcgctgg tgtgtttata attgtaaaga ctctaccttg tttttctgct atatttacaa
    21001 atttttcttt aaacgactca aaattaaacc ttctattttc atcaaaaagt tggtaattaa
    21061 ctacttttct attagcctct tcagctatac ttacatatgg actccagaac caatcagatg
    21121 ttaatacctc atctccttca ttagtatagt tccatacagc taattttatt gcaccacttc
    21181 ctcctggtga agctaatact cttatatgtc cttctggtaa gtaatctctg aaaaatactt
    21241 ttttaactgc ttctaagtaa tctggttgac cttcaagagc tgcatatgca cctatctcac
    21301 agttatctaa tgctttatat tcttcatata cagttttcat tgttatcaat tttcctgaat
    21361 catccattag agcgcctatt gttgcattta ttacattatc cataccaaaa gccttctctg
    21421 ctgcttgagc tctgccagat atgctaaata taacatcatt ttcttttggc cacattgcat
    21481 gcttaccaac catactttga ctcataccat cacccctaaa attgtattta ctcttacatt
    21541 atatattaag caattactat gccaataaat cccactttat gtaaaattga ttttgtttag
    21601 aattattatt tttttcatta ttaaattaag tgttttaact atttttctta taaatatata
    21661 tgcctgtcta aaaaaataaa aatttgcaaa aaagtaatgt taatttttct taacacttgt
    21721 tttaaaaaat taacattact tcaaaataat ttatatgtaa ttatatttaa atatttttat
    21781 tgtatttctt ccataaagat gtcctgctta ttccaagaac ttgtgcaact tcatttttag
    21841 aaagtccttg agcaaaaagc atacttatta ttttttcttc aacatactta tttacttctt
    21901 ttatatctat acttatctta ccatcattta tcttacttat atttatagat tcatcttgga
    21961 cttctacact tgctgtcgtt tcagaattaa atttgtctac ttcagagtta ggaagtaatt
    22021 ttttagtttt aaaatctcta tcttgtctca atttaatttt acctgtcaca acatattttt
    22081 gagctattgt ctttaactct cttacatttc caggccagct ataattatat agcttatcca
    22141 tttcatcttt agtcaaaaca aaattttcat ctatactgtt tattccattg agaccatcat
    22201 cctttaatac ttcatttaca aaattgttaa acaaaggtat tatatcttct cttctgtctc
    22261 ttaaaggagg tatatttatc tctaaactac tcaatctata aaataagtct gctctaaatg
    22321 tacccataac tattttttcg gttaaagatt cgttcgttgc tgctataatc cttatatcca
    22381 gaggtattat ataatcagaa ccaattctca ttatttgacg ttcctctatt actcttaata
    22441 gttttgtctg aatattaaag gatagactat ttatttcatc taaaaaaaga gtccctccat
    22501 gagcaagttc aaatagccct ctttttccac cctttctagc accagtaaat gcaccttctt
    22561 catagccaaa aagttcactt tcaagtaaat tttctgctat agtagcacaa tttatagcaa
    22621 caaaaggcct atcttttctt ttacttatat tgtgtatact atgagctata atttctttac
    22681 cagacccact ttccccataa agtaaagttg tataatcact ttttccaatt tttttagctt
    22741 cttcaataaa ttctttagtt aatttatctt taaataaaaa atcatcaaaa gtatatctag
    22801 catagagacc tttttgattc aagtcaaatc ttatttttct ttctaagttt tgtagcttgg
    22861 ttatatcttg tattattcct aaaactccat aagtactatt atcaactttt atcaatgttg
    22921 tcctagtatt aacaattaga ttatttatat ttcttatctt tctatcttct acgtcctctt
    22981 tttcatgtaa acaatctaac atccactcca ttttaggaaa tacatctaag atgtatttat
    23041 taagtgcaca ttttctctct actttaagca tgttttttgc actttcattg tacaaaatta
    23101 tactgccatt actatctata gcaattactc catcttttat accatcaagt atatttcgta
    23161 acacttcatt attaaacttt tcttcaccta atgtatctaa taatttttta caatattcta
    23221 cagcttctct tatagattca tcactagcag ttgcaaatac actatcaatt ccatattgcc
    23281 ttgcaaaaga acatgccaaa cctcctccta cgattacaat ttcatctttt tggtctatat
    23341 attttacaac tttacttctt atctcatact tagattcaaa ccattcttca gttatttcag
    23401 tacttatgac atttctccag ccaacatagt caaaagaaac ttcattgtct ccaagaatca
    23461 atactacttt tttagaatat ttctttgcta tttctattgc tcttaaaagg tcagttgact
    23521 tcatattcat tggtataaca ggtacattta ctgtatctat tactaaacta taacctccac
    23581 ctctaccaat tatagcttgg gcaccttttt caacaagtat acgaccttga ttttccatta
    23641 agtctaggtt aagtatgtcg attattatag ttccattttc tacatcttct ctatataatt
    23701 cttctattct ttcttttaat tcaatatcag aggctataat tcctattttt tttcgcaaca
    23761 aaatcacctc aattttaaat tataatgtat tgatttctac ctgctttttt tgatttatat
    23821 aggttcttat ctgcatcttc aattaatatt tcaacatctt ttctactacg acatcttttt
    23881 atacttactc cagcacttat agttatatag ttttttattt tagaatatat atgttcaata
    23941 ccctcaaatt caagaagttt gaaaactctt ttaatatata attctatatt atcaatctct
    24001 tcaacaccga ttgattctat agaatctact aatattaaaa tttcttctcc cccatatctg
    24061 attatgtgtt cggtaatatc tataaataca cttcttataa tatcagttac cttaactata
    24121 actttatctc ctgctagatg accataatta tcattataac ttttaaaaca atctatatcg
    24181 accagtattg cgaccatatt tttgtctctg gtttcattaa ataaatccaa ctgctgttcc
    24241 agatatcttc tattatatag tttagtaagt ccatctttta aaatatcatt ttctaatttc
    24301 ttattatcat ccactagtaa tcttaaactc tcttgttttt gtctgagttc atattgtttg
    24361 tgaattgctt gagatgtttt ataggaatta tttttttccc acctatcaga ataccaatcc
    24421 atacttttat aatattctat tgccagttta aaatcttttt ttagctcata tccatttgct
    24481 attagcccat aaaatataga tatttttcta agattcaatg aactcttttt aactaaattt
    24541 aaacctttta tataacaact tataccttca tctatattac caaattttat atataaatct
    24601 ccatacaact tatatatgta atctagttta gaattatata taaaaacatc tccaaaactt
    24661 ttatatatat tttttgataa aattaaatag gtgtttacct tttcaaaact acaattatct
    24721 ttctttaact caatttcagc tgaatataaa aatataaatg aatataaata atccttatat
    24781 acaccttcaa caactttcat taattttata gtctttaata aaataacttc tgcttcttta
    24841 ttcatatctt cttttaaata tgcccatata aggtctattt ttatagacac tctttcagtt
    24901 actgatattg agttattact gtgtgcaaca tctaatacat tatttatgta ttttatagct
    24961 tctacattat ttccactctc taaataacac aaacttatta tacatttaca aaaagcctct
    25021 atagagtata aattattttc ttgagccaat tttagacatt caattaagta ttccatactt
    25081 tttataaagt tattaaataa atatagataa actctcccaa atatataatt tgccctactt
    25141 acaagagctt tattttttaa agttttaaaa aaagacactt cttctactaa agctattaca
    25201 tccgttttgg tctgatataa agcacttatt tctacacata aactcatatt taacaatacc
    25261 aacaactcat ttaaatgatt ttgtcttata attttttttg ctgagaaata aaaattattt
    25321 accttatcat attttcttat agaaatagct gataaagtaa gataaatata aattttagat
    25381 attatatctg aatcatcttt taatgacaat tttttaatat actttaatga ctctatcaaa
    25441 tagttgtatg atgcttctct atcttttttt atatagttta taagactaat taaatataaa
    25501 gtatagactc tactattatc ttctaatttt gtatttaaaa ggtctttgtg ataatccaag
    25561 atgtagttta aatctgtcaa atttagatag aatttagtca acatatcgta ttctatcttg
    25621 tttatatttc tctttaaatc ttctattaaa ctccttttca agtaaatcac caatcctatt
    25681 tcaacagtta aaaattctta aaatcatgat aatgcaaaca tctatttcta ccactttcct
    25741 ttgctttata taaagcttta tcagcatttt caattatttc ttttatatct atactactat
    25801 ttttacatgt atcaatgcca atactaactg tcaaattatt gtttaaaaat ttctttacaa
    25861 tcctacataa ttttcttcca aatattttac tttttttata atctttacat acagataata
    25921 tcagaaattc ttctccacca taccttatca taagcatgtc tttttttaga tattttttta
    25981 ttattatagt tatattttta agagcaatat ctccattata gtgtccataa gtatcattgt
    26041 attctttaaa gtaatctaca tctatcataa atgctgtgca atattcacta acttcttgtt
    26101 tttctaaaaa atcgttcaaa aaagttctat tatatgcact tgtcaaatgg tcaacatact
    26161 tttttttatc taaatcaagt tttacttttc tcatgttatt tatttctttt tctatatact
    26221 catgtctata atttaaggaa tctatataat ttctatttcg agcttttata tacatcattt
    26281 ttaactcata atacatttta aagtatttca tactcatttc ataattttga atcttttcaa
    26341 aacacaaata tatactcttg tatgctaact tcacataatt ataattttta gcatttttag
    26401 atttttcaag gagtttttta tttgtattta aggcattgtc ataatatcca aagatataat
    26461 atatctttgc ctggtgataa attatttcta aatcatatat tatatattct tctatatttt
    26521 ttatcatatt taatatgttt ttagctctat ctaaatagca tattgattgt tcaaaagatt
    26581 tttcattact ttttgcataa tacatggcta aacttataaa taaatcaaac ttctctactt
    26641 cttttaagct atgattttta attttttcta gatatacttc agattttgct aaattattta
    26701 ttgcgacagg ataatttcta gtctttatta atattttagt tatgttgttt gatgctctat
    26761 atttttgaat tatatttaca tttctatact ttttattgct tattacttca ttgaaatatt
    26821 ccatggaaca ttcataattt tcaaacgaac attcacactc acctatcttt atattacata
    26881 gtgaagatac ttgcatatcc tttagtaaat ctgcatattt tcttgctttt aaaaaattta
    26941 ccttagcaat tagagcatca tccaaaaaca aaaaatatat tttaccaata ataaaaaaat
    27001 atattttttt acaattaaaa tcgttaattt cttttatctt tatatacaac gtttctattt
    27061 ctttaattat tacagaagat tctatacact tacttgcctt aatgtaaata agttgtgatt
    27121 taaaaataat ttcttcaatt agaaaattat tttcatcaca aataagatta aatttatcca
    27181 tatataaatt tgccttattt acatcttcat tttttaaact taaaatagct atttgtgaat
    27241 aaaatcgtgc taaaaattta taatcttcgg gtaagcattt atcaatatat ttacaggaaa
    27301 tcaaaatata ctctttcatt ttttcactaa acccttgaat accatataat aaagctagca
    27361 aaaaatttga ttttaataac attaaactat tttgttcagt tttatagcaa tcaattaaat
    27421 tctttactac atcaatttta ttttcaataa aatcgttatt agtcaataat ctttcattca
    27481 aggttagttt aaacattgaa tctaaaattg tatcatctat ctcttccaaa tatttactat
    27541 atattgtaac tcacctccga cttacattat ctcataaatt tagtaatttt ccatactatt
    27601 tttgaaaaaa gttgatgtct caatttagaa atttctctta aattaagaca tactttacac
    27661 taaactatac aattttctat ctgaactata taatcctgac aattttcgca aattatcaca
    27721 cttacaatat aactattatc aactttattt gcccttgata gtttattaaa agatagtcct
    27781 ttataatcaa cagatatatt gcttattaca tattctccat ctttactgaa aatataaaag
    27841 tgatattcta aaaaaggaaa gaattttttc ttttctttta ctccttctaa acataatgga
    27901 catgcttctt gataatattc tacatcaaaa tcaacttctt ctgcttcatt aagtatatca
    27961 attatttttg aaatacttac tccttgaact ggattttctt catcatttat taaagcacta
    28021 cagttctcct cttttaataa atattcctta tcatcatata taaacttata taaactcata
    28081 ttatatcctc cttataatta ttaatctcca agttattcta ccatttaaat aaagttaata
    28141 aaagtaattg tttataatct ttataattaa gttatgtata catatattcc tatgcgctat
    28201 cttaattaat gattttaaaa tccaagtttg cactttgaac atccagtttc ccaaaatcta
    28261 ttgtcaaaac tcactttagt tattaatata atgatataaa tatataactg catagatgtt
    28321 acacacttaa ctatttaata tgatacgatt tggtatctaa atttatatat tgtatatagg
    28381 gggagatata tatgtataaa gataaaagtg atgaatgtat acacttaatg actgcataca
    28441 tcgatagtat aagtggatat tattcattta ttgacacaca attagaggat tttatgatga
    28501 aatatggtga aaacattgtt gattcaaatt tacacagtat aatgatgttg ctttgtaaat
    28561 ggggattatc ttagcatttc aagaaacttt tttgtatatt gtattctata ttatttattt
    28621 attaacaaaa aagattgaca taaacttaaa agctatatat agatttcttt aaaaatctat
    28681 atatagcttt tttaattttt tcaaaatgta tacttaaata agttagtttt tttcaaaatt
    28741 tgactatcta atatgatata atttaactat ctacaacaat aaaaaatatc taatatgtat
    28801 tatctagttt agctcatcat aataacatcc ctatatttac aattaagata ttttcaatat
    28861 agtaataatc aattttaata ttataaaaag gagagatttt gtatggatta caatgactta
    28921 ctaaaatcag ctagagagaa ctttaatgga acatgtaaag tatgtaaaat ttgtaatgga
    28981 ttagcttgtg ctggagatgt tcctggtatg ggtggtaaag gaagtggttc gtctttcatt
    29041 gaaaatagaa aaagtctaga aaaaataaag ataaatatga gagtcataca taatgtttca
    29101 aagccagata catccataga attatttggt agaaaaatga gttctcctat attcgctgca
    29161 cctgtatcag gtactatatt aaatatgggt ggtaaagttt ccgaaaaaga atacatagag
    29221 cctgttgtta gaggttgttc taattctgga atttatgcta tggttggcga tactaatgta
    29281 gatacttttt tactggataa tttagatgtg ttgaaggata atagaggaaa tggaattgta
    29341 tttataaagc cttggaataa ttcaaagata atagaaaaaa ttagattgtc tgaagaagca
    29401 ggtgcttttg cagttggtgt agaccttgat gcttgtggac ttattaataa tcaatttcaa
    29461 gaaaatcctt tttctcctaa aacaattgat gagattagag aattggttga atccactaga
    29521 ttacctttta ttataaaagg aattatgact gtagatgatg ctttgatggc tgtagagtct
    29581 ggtgctagtg ccattattgt ttcaaatcat ggtggaagag tacttgatta tactcctggt
    29641 acttgtgagg tacttccaga tatagccaag tctgtaaagg gaaagataac aatacttgtt
    29701 gatggtggag ttaggactgg tgttgatgta gttaagatgc ttggattggg tgctgatgct
    29761 gttttgatgg gaagaccttt tgttactgct tcttttggcg gtggtcttga tggtgtggag
    29821 ttttttatag agaaggttag gaatgagtta tgtgagacta tgattttgac tggttgtcaa
    29881 aatgttaagg atatagatgg tagagttata tggaattagt tttaaaacaa atttatattt
    29941 aaatattctg tcaggtattt aaatataaat tgtgtattct tacaaaaaat agtgataatt
    30001 aaaatctcaa atattactat acaaattatg gtagacactt tttatattta acaaaaacaa
    30061 aatattagct aaatttattt aataatataa tattaaaata gatacaaata tacaatatat
    30121 gttaaaatat ttattcataa gtacaattca ttaatttgtt agaagcagag tttgaaaaaa
    30181 taaccttaaa tatttcaagt taccttaaaa gtatttgcag aattgatata tctcattcac
    30241 taattgctaa aattactgat ataggtatac ctttcattca tggatgatag aatagaacat
    30301 ttgatattat ttatccaatt atatttatga attaaacata ttataaattt agaagtaaaa
    30361 gtataataat aaataacaca gtgtatagct attgatgtca acttataaga tataaagaat
    30421 acattagtaa tattaattag agaaaataaa agttcaaaga attacctaaa attacttgca
    30481 gaataggagt taaagataca ttaataactt atgtatctag tctaaatgga ttttccttaa
    30541 aggagtaata acttttgaaa aaatatataa ataagactat aatttttata aacatagtct
    30601 tatttataaa tatttaattg tcattttaaa aataaaattt cattaaaaga atatgcatga
    30661 atatttccag actccagact cccatgtttc tttttagctt tataataaat tatctaagca
    30721 ttagtaactt gtgccaactt attccatgtt cctaatccaa ccacaccatc aacacttagt
    30781 ccatatttac tttgaaaact tctaacttta ctatatgtag aactaccaaa caaactgtct
    30841 attgctatag aatatcctga tttttttagt aaaagctgtg ctaaatgtac tggatttcca
    30901 ctagttgtat gtccgtatcc cacatatgta ctaactccaa ctgtatatgt ttttgcacca
    30961 gtaacttcaa aacgtgttcc aaaatattta acattgaatt catctatttc aaaaagagga
    31021 acagtatctg tatacttaga gatttcatct attggaataa atatttcagt agatggagaa
    31081 ggtgttatat ttaattctct acatgttttg ttatattcat ctttaattct ttgtggtgca
    31141 ttttcatatg taaatgtata accttgaata ttaaattcat aaattggatt ctcaacagat
    31201 ttatcattta tttcattatt attttctaaa tctgcaaaag atatactccc tcctaatatg
    31261 aataaacagc acgctattga tagtactttt ttaatttttt ttaacataaa atcctcctaa
    31321 aatattttct tttatttaaa ttattacatt ttttaataca atttaacatc atctttcaac
    31381 tcggatatca gtgttgtaaa tatactcatc atttaacaca cttggcttcg gtaatgaata
    31441 aatcactggt tttgaaataa atatatcaaa tttaaaatat gttattgaag atagtaaaca
    31501 taaaattata actacaaaaa cactattttt aaacttttta ctaataatac tttcaagtct
    31561 cttttctaaa ttggttctat taaaatctgt taatagaata cctctattgc attctttact
    31621 tagtttaatt gatttaataa gtgccaatgc atattctttt ttgtcattaa atgaacaatt
    31681 ataaataaca ctttcatcac aacataattc acaatctaga tttactctat tgctcattac
    31741 ataaacaagt ggattaaacc aatatattat tctaacagac aaaactaaaa actttattaa
    31801 aatatcttta tttttaaaat gcattaattc atgtttcaaa atccaagtta actcactctt
    31861 actataagaa tagtctggta agaatatgta agatttaaat aatcccatac ctgctggact
    31921 tatcaattca tcagaacctc ttaattcaat tttctttttt atatttaatt cttttaacaa
    31981 gtttttgtag atacagttta tatcattatc ttcaatatca taagatacat caacaactag
    32041 atttttaaat cttgtatact ttataaatgt ataaactgca atgactatag ttacaaataa
    32101 ccataaataa gctacataca gcataagatt attatctgta gaaatatcaa tttgtgtaat
    32161 attatttcct aatgcatttt ctttgggttc ttttacttca tacactattg tataattaaa
    32221 tagaaaaagt aacattctaa agactattat caaccaaata taataattga atctcttact
    32281 aaacttctta aataaatatc ttttcaaaaa taataataga caaataccaa gactacatac
    32341 aatagttgtc tttataagat tttcaaaaac atatagcata taattattca tcctttaaat
    32401 tatcaaaata actttctaga aaatctagct tatctttacc tatattttcg tcatcatgta
    32461 atgctgaaat taagcttctt aaagagtcat catgtatatt acttaggaaa tcctttgtct
    32521 caaaacttaa ataatctttg tgttttactc ttattgtgta atgtgtatat ctgtctattt
    32581 tttgagcatc taagaatcct ctttttacca gcctagataa aagtgtcagt gtggtggttt
    32641 gtttccagcc atatttttgt tccatagctt caataacatc ttttgatgtc actgtaacat
    32701 ctactttcca aataaatttc attactttta gttctgcttg tggtattttt cttatcatta
    32761 tttacacctc cctcaaaact cctgctacct taattctaca acatgtgaat tttttagtca
    32821 aacactttat gaaaaaaatg tgaatttttg tactttttgt taaatttcta atttttttac
    32881 aatattaaaa gttagatttt aaaatatatc tatttaaata ttttactttt tacatattta
    32941 attacaatag tgtagaatgt tatttacaca ttaaaactat ttaataaaaa ttcctatatt
    33001 ttcacacaag gaatattata atactttttt ttaaaataaa ctagagt
//
LOCUS       DAEQAF010000041        32627 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.042, whole genome shotgun sequence.
ACCESSION   DAEQAF010000041 DAEQAF010000000
VERSION     DAEQAF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32627
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.042"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            65..763
                     /locus_tag="KRN00_001973"
     CDS             65..763
                     /locus_tag="KRN00_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827839.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKNAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            941..1831
                     /locus_tag="KRN00_001974"
     CDS             941..1831
                     /locus_tag="KRN00_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827840.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLKKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGGSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(2233..3189)
                     /locus_tag="KRN00_001975"
     CDS             complement(2233..3189)
                     /locus_tag="KRN00_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1827841.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIHFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            3892..4887
                     /locus_tag="KRN00_001976"
     CDS             3892..4887
                     /locus_tag="KRN00_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1827842.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            4865..5728
                     /locus_tag="KRN00_001977"
     CDS             4865..5728
                     /locus_tag="KRN00_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH1827843.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            5725..6519
                     /locus_tag="KRN00_001978"
     CDS             5725..6519
                     /locus_tag="KRN00_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBH1827844.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWQQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLVMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            6804..8183
                     /locus_tag="KRN00_001979"
     CDS             6804..8183
                     /locus_tag="KRN00_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1827845.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVGQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTVFCIF
                     KYKNRYKYM"
     gene            8632..9345
                     /locus_tag="KRN00_001980"
     CDS             8632..9345
                     /locus_tag="KRN00_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827846.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(9617..11155)
                     /locus_tag="KRN00_001981"
     CDS             complement(9617..11155)
                     /locus_tag="KRN00_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBH1827847.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIANNFYSIDNEINKIANGLGLDSIGMNRVVREL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSRLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRRKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWVDKIFNIE
                     KQLV"
     gene            12037..12492
                     /locus_tag="KRN00_001982"
     CDS             12037..12492
                     /locus_tag="KRN00_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH1827848.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSSLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            12541..13125
                     /locus_tag="KRN00_001983"
     CDS             12541..13125
                     /locus_tag="KRN00_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBH1827849.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSGVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(13130..13453)
                     /locus_tag="KRN00_001984"
     CDS             complement(13130..13453)
                     /locus_tag="KRN00_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827850.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            13605..14123
                     /locus_tag="KRN00_001985"
     CDS             13605..14123
                     /locus_tag="KRN00_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1827851.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            complement(14299..14967)
                     /locus_tag="KRN00_001986"
     CDS             complement(14299..14967)
                     /locus_tag="KRN00_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827852.1"
                     /translation="MLEISHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            15082..16497
                     /locus_tag="KRN00_001987"
     CDS             15082..16497
                     /locus_tag="KRN00_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1827853.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAGFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            16720..17178
                     /locus_tag="KRN00_001988"
     CDS             16720..17178
                     /locus_tag="KRN00_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827854.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            17175..17759
                     /gene="clpP"
                     /locus_tag="KRN00_001989"
     CDS             17175..17759
                     /gene="clpP"
                     /locus_tag="KRN00_001989"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBH1827855.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            18071..19147
                     /locus_tag="KRN00_001990"
     CDS             18071..19147
                     /locus_tag="KRN00_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBH1827856.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGDPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            19214..21280
                     /gene="bclA3"
                     /locus_tag="KRN00_001991"
     CDS             19214..21280
                     /gene="bclA3"
                     /locus_tag="KRN00_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBH1827857.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGFGVTGPTGPTGATGI
                     GITGATGLIGPTGATGATGATGPTGVTGATGAAGLIGPTGATGATGADGATGATGATG
                     ATGPTGADGLVGPTGATGATGADGLVGPTGPTGATGVGITGATGATGATGPTGADGLV
                     GPTGATGATGADGVAGPTGATGATGNTGADGATGPTGATGPTGADGLVGPTGATGATG
                     LAGATGATGPIGATGPTGADGATGATGATGPTGADGLVGPTGATGATGATGATGPTGA
                     TGPTGPTGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNA
                     AGTLTNFAFSMPRAGTITSISAYFSTTAALSLVGSTVTITATLYQSTAPNNSFTAVPG
                     ATVTLAPPLTGILSVGSISSGIVTGLNIAATAETRFLLVFTATASGLSLVNTVAGYAS
                     AGIAIN"
     gene            21449..22210
                     /locus_tag="KRN00_001992"
     CDS             21449..22210
                     /locus_tag="KRN00_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH1827858.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKMGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            22519..22797
                     /locus_tag="KRN00_001993"
     CDS             22519..22797
                     /locus_tag="KRN00_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827859.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            23090..23665
                     /locus_tag="KRN00_001994"
     CDS             23090..23665
                     /locus_tag="KRN00_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBH1827860.1"
                     /translation="MKKITWEVEYISQLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            24104..24814
                     /locus_tag="KRN00_001995"
     CDS             24104..24814
                     /locus_tag="KRN00_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827861.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            24808..26124
                     /locus_tag="KRN00_001996"
     CDS             24808..26124
                     /locus_tag="KRN00_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1827862.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            26136..26276
                     /locus_tag="KRN00_001997"
     CDS             26136..26276
                     /locus_tag="KRN00_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBH1827863.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPEALQKL
                     KK"
     gene            26335..26916
                     /locus_tag="KRN00_001998"
     CDS             26335..26916
                     /locus_tag="KRN00_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBH1827864.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            27173..27547
                     /locus_tag="KRN00_001999"
     CDS             27173..27547
                     /locus_tag="KRN00_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827865.1"
                     /translation="MNLKKKIKKLGVTFAIGTIIVSSLGTSVFADEVSTYALISKAFS
                     GKNNIISSSVYTSGSRTFKTTDSQGGFSCRLTERFSGSSPDRIVKRHEANASSKVSLS
                     GGTYYIRYEGSTNNAKTYATLN"
     gene            27630..29339
                     /locus_tag="KRN00_002000"
     CDS             27630..29339
                     /locus_tag="KRN00_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827866.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITVIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTNMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKVNSENIKFNIKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSYMAYKINLSSKNNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            29354..30226
                     /locus_tag="KRN00_002001"
     CDS             29354..30226
                     /locus_tag="KRN00_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1827867.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            30227..31015
                     /locus_tag="KRN00_002002"
     CDS             30227..31015
                     /locus_tag="KRN00_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827868.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(31111..31944)
                     /locus_tag="KRN00_002003"
     CDS             complement(31111..31944)
                     /locus_tag="KRN00_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBH1827869.1"
                     /translation="MNVENQSLSDIEIILSHRYDNGADYWTTPDKRLIKGSPFSTLDS
                     VLYLLELGVNPDDTLLKECADLIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGY
                     ASDIRMQKTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLN
                     KESKLDKAVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRA
                     KKDNRFLEALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLE
                     K"
     gene            complement(32012..>32627)
                     /locus_tag="KRN00_002004"
     CDS             complement(32012..>32627)
                     /locus_tag="KRN00_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBH1827870.1"
                     /translation="TKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRFTLNFF
                     DRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIPGGNVY
                     YPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMVFILWF
                     GDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAIDAILNKINQL"
BASE COUNT        12445 a         3717 c         5275 g        11190 t
ORIGIN      
        1 ataaaatata attaagttaa gttggttttt ataaacataa atttatttta gggaggtgaa
       61 ataaatgaaa atatctagtc aatatagaag tcaatattca tttagatatg aaagtaatat
      121 aaataataca agaataaatg aaagtatggt taagaaaaat gaaactgtag gaaaagacac
      181 ttatttatct aatattatga aacaaaagca agaacttaat gatagaatta gagatttaaa
      241 atatagacaa gaggtttata ctaaaaaaat aaatgacgca attaagaact tatgtaaatc
      301 agaaataaga gaaacaacta ataacttttc taatatagaa ataggtatta aaaatagcat
      361 tatagaagat aaaaataaaa gtacaatgtt agatgaaaat tcaacttatc taaatacaaa
      421 tgatgaaaaa gaatctttaa tcactaaaga gtctaatgaa aaaattgaag aagaaatatt
      481 aaatgatgaa aaattagaag agttagaaca aaaaaaggat tataaagagg attctaataa
      541 aaaagagaaa gtatctgagg acttatcttt agtaggtaaa actcgtgaag agcttgaaaa
      601 tatgcttaaa aattttataa atttaacaca agaagaaata atgaaacttg agtcgagaat
      661 agaaaagtta gataaaaatg ctgaagaata caaacaaaat tcaaagacta atatatttga
      721 taaaacagat gaacaaaaaa aacatataaa tgtactgatt taaacaatat gttttaaaaa
      781 aataagttta ttatataatg aaaatataaa ggtacaattt caatacactt ctattaaacc
      841 aataatttat gaatcagatt taatttcaat ttactaataa ccatatattt atgagttaat
      901 aattttatgt tttaaaaaga attaaataag ggggagtagt atgaagaaga atatattaac
      961 tactatgatt accatgatta ttatattgat gatgagtatg acagtaatgg cagagccata
     1021 tcaagaagat gaaacatcta gcttgaaaaa acagagtgca aatgaacgta atcagactaa
     1081 tataggcaca atggatggca gagtgcaaac aaatgcaata agtaaaggtg ctaattatga
     1141 ccctaaatat cctcttaaag gaatgttaac acaacttggt cttaatacaa caggtaaaga
     1201 gggatgggat ttactctatg gaggaaatcc caatggagtt gagcttcgag cagatggtaa
     1261 atattattat ataaataagg gtatggaagg tctaggattt tatgcggcag cattgtcagg
     1321 tggctcatat cagagaatag gctttggaaa acttgaccct atagaagtaa tagctgatgg
     1381 aaattggatt tcttacaaac aagctcaaga tacacttaca gtaataagga attttttaaa
     1441 tagttttgac tggagaaatg catctgagat ggaaagagct aatagagctg caaaattggt
     1501 aaccgaagca aaatatgcag actctaaata ttgtaacata gtctatggta atctggttga
     1561 taaacgtggt gtatgtggaa gttttgcaag tagctttcat ttattaacaa ggttaatggg
     1621 aatggattca ctatctatat taaatccatc attaaatcat gcttggaact atatacaaat
     1681 tgatgggaaa tggtataggt ttgatgggtc tgaaatatca gcttttggtg gatcattaga
     1741 ctttgattac cgtaaattaa aggatgcaac aagagagatg actacttact atgatgcaaa
     1801 ggcattgtct atattaggat ttaatcaata aaaatagggg gaggcttctt atagagcctt
     1861 tttttattga tttgaaattt aataaggaat tttatatgaa aatttaatca ataaaagcaa
     1921 aaaaggctct ttataaagcc tttctaagtg tttttttaag taaaattttt tatatcaaga
     1981 tcagttttaa tcaaaacata taacattttg gacttacttt taaaaataaa attattaaaa
     2041 tataatatta atcatgttaa taatgttttt agtttattat attctataat agtggtcatg
     2101 ttgactactg tagttttatt aagaatagtt ggtttatata aatatatgca aagatagctt
     2161 gttgtttact ttacttatta gtatatagga caagatactc taataaattt gcctatttta
     2221 atatcttttg tactaaaacc aactaaagtt tcctttatta tttcgttttg aataatacaa
     2281 agcataatcc gattgtttgt ataaagactg gaaagtatca gagttatttt ctaatttaga
     2341 tatacctata gaacaagaat tactctctag gcataattct aaaaccttct ttgccttatt
     2401 ttcaacattc tcttttgatt gattactata ttcaaaaaca gcaaattcat ctccaccaag
     2461 tcttccaata atagcatcat ttacgaatac tttagtcaaa atatttgaaa aatgtattag
     2521 tatttcatct cctcgaacat gaccaaagat atcatttacc tgtttaaaat tatctaaatc
     2581 aaagatgtaa aagtatccat gtgaaacagt tttaagcatt tcttttatgt gtacttcaaa
     2641 aaaatgtcta ttgtatagtc cagtcataag gtctttttct gattttagtt taaattcatt
     2701 tgccattgct agtgcttctt gtgctttttc agttattgtt ttagggtaat actcatcttt
     2761 catttggtca aagtttggaa tagaatggtg aacatggata agtttaatca tatcatctgt
     2821 aactctgtat accatagtaa atcgagtatc catttctaca tagatatctt tttctaggta
     2881 atctttttct attacccaaa gagtaccata tactataaaa gcttcgtctg taactttggt
     2941 acatgaatac cactcatcta taatctcaaa gtctatttgc tctgattctg tttggtcttt
     3001 ttcaagacct ataataaatt cttctaatgt ttcgtaaaat tcatgttttc ctgttccaat
     3061 taatgcaagg ttgtcatcta ataaggaaat aataaattta aggttttctt cttctggatt
     3121 taaaatataa atatgccaaa ttttttttga taaatctctt aattgttttt gtattgtatt
     3181 attttccata gattaccccc ttaagattta cagtttatat tttaatgtat tataagttga
     3241 actcttatta caatattatt ataatataga actaaagaaa ttacatcctg tataggtaaa
     3301 agtatatctt ttacaataaa aatattacag taaaatgacc agttttaata tacgtattat
     3361 atttttaatt tataaacgaa tattataaat gaaatttaaa ttcaaccttg aagaaataag
     3421 ctaaatgtat tagtatatta atccatgctt gaacataaat aacctttatg atatgatatc
     3481 aataataata ttatgagagg agtgccttga tgtcggagtt atataatggt aaccaacaat
     3541 taaatagttg gagacacata tattctgtat aatcagaaat ttcaagtgta tttttaatac
     3601 atttaatttt tgtgtcttat tctgccttta tagataactg acatatgaca acaaatagta
     3661 tttaaaatat atattacttt gttaaattat ggtgtagtag gctttaatct gctacacttt
     3721 tattaatttt gtatagtatt attttgataa ctattttgaa atagagagca ttaatttttc
     3781 tagtccacag gagttttctg tttttgtgct gttaaatata agcacagaaa aaggcagata
     3841 tatacctgtg gacttttttt atataaatta tgaaatatgg aggtagttaa aatgagtata
     3901 attgaactta atgaactgac taaatcttat agaagatttg agaaaaaggc aggatttatg
     3961 gggagtgtaa agtctttatt taataggaaa tatacagaaa aaacagctat atcgtcattt
     4021 gatttaaaga tagaagaagg agaatttgtt ggattaatag gtcaaaatgg agctggtaaa
     4081 actactctta ttaagatgtt aactggtatt attgcaccgt cttctggaga aatatctgta
     4141 atgggttatt accctaacaa attagaaaat aattttaaaa aacaatatgc tgttgttatg
     4201 ggccaaaaaa gtcaactatt ctttgaattg acaccagcag atacgtttct tttatttaaa
     4261 gaattatatg atatatctaa tgaagaatat aaaaaaaact tggattactt tatcgaatta
     4321 tttgaggtat ctgactattt aaatgttcaa gttaggacgc tttctttagg agaaagaatg
     4381 aaaatggaac taatagtagc ccttctacat aatccaaaaa tattattttt ggatgaacca
     4441 actataggct tagatgctat agcccaaaaa caaattaggt atttcctaaa agaagtaaat
     4501 gaaacaaaag gaactactat tatacttact tctcattaca tggaagatat taagagtctc
     4561 tgtagtagaa gtattgttgt agaaaatagt cgtaaaatat atgatggttc tacagagaaa
     4621 ttatttaatc attttcaaaa atataaaaaa ataacagtta gtttttccaa tgaaactaac
     4681 attgtatttc caaaagattg taaagttgtt gaacaaacaa atcataagac atcagtaatt
     4741 gtgccaaaag aaagaggaaa tgaaacgatt aaatggattt ttgataaata tgatgttaaa
     4801 gatgtaatga ttgaagaaga agatataggt agtattgtag agagaatata taagaaagga
     4861 agtgatgagt attatgagca actataatga agcaagttca aattattcaa tgttttataa
     4921 atttaaacag agtattagaa ggtattatga agtagccaaa attaatttta aagtgcaact
     4981 tatctggaga tttgatgtgg tggttaatat ggtgtttacg attgtaaaaa ttttatttgc
     5041 ttatatttta tggaaagcaa tttttggtga aaataaaata gtctctggtt ttacatttaa
     5101 ctctatgttg tcttactata taataagctc atttttagca ggtattgata tgtcaaagag
     5161 taccagtgaa gagatatgta atcgtgtaaa attgggcacc ttttcaaagt acatgattat
     5221 tccaattaat gttcaaaatt attttattgc taaaaatttt ggaatgacat gtttttattt
     5281 tgtatttaat atgatttctg catttgtatg gatttttata tttaaaatag attttgcctt
     5341 tacatcaaat ccagttcaaa tattaatttc aattttgatg atttttctag ggtttatttt
     5401 tatgatgaaa ctccacttct ttattgggat tttgtcattt aaatttcttg agattagttt
     5461 ttttagaatg ataattgaaa atattgttga atttattaca ggaacaatga taccacttgt
     5521 actcttacca gaaactatag taacagttat gaaggtattt ccattttatt atacaacata
     5581 tttgccatct atgttactaa taggtagaaa cagcaatgag gcaatacaag gattaattat
     5641 tctagcatta tgggttttat ttttttctgt agtaaataaa gttatgtata aaagaatgag
     5701 aacattattt gatggggtgg gtatatgatg aaaaaaaatt tgaaaataat atttatgtta
     5761 ttaaaaatga aattatcaaa gatgatggta tttagattcg atttttttgg agcatttttt
     5821 gtagatagtt cattatttat attacaactt ctaatgttta atagtatata ttctcatgta
     5881 gactcaatag ggggatggca acaaggagag atgttaatat ttataggaac tttctcatta
     5941 ataaatgcga taaatatgac gattttcttt tttggtattt atgatattcc acgaaaaatc
     6001 caagaaggag aattagacta ctatattaca aaaccattag acccactatt taggttaaca
     6061 tttgaaaata ttaatattgg ttcatcacca ttaattctag caagtatact tattgtttta
     6121 tatggaatat ctgagttaaa ctcagagata actttagtta tgataataat atatattttc
     6181 atggtgttat tgatgacatt acttttttat gatgtatgta tcatacttag aacagtttca
     6241 ttttttgtta tatcatcttc tgcgataatg agattagaag ataatttatt gccaatgaat
     6301 atgaaaattc ctggtgtaat atatgaaggt gtttttaaag tattattcta tttaatctta
     6361 ccatatggaa ttatgtcgac aattccgact caaattttgg ctgggacaat aacaattaat
     6421 ggattaatat actcaatttt aattgtattt ttgtttacat tgtttatgtg gagattttgg
     6481 aagttaggta tgagacatta taaaagtgca agtagttaat aaattagtaa aaatagacaa
     6541 tgtataacta tatataaata cgtttcatat gacactaaac tatgtgaaca agtatttgcg
     6601 ctaaaggcac tgaaagctat aaaatgatta aagtaaggat ttaaaagttt ctttagtaga
     6661 aatataattg tgtaaaaaag caagattaat taaaactata tccaaataat tagatataat
     6721 tcttatgcag aaaggaggtc tgtaaatgtc taattgtttg gaatatattt taaaaataat
     6781 taatgtacag aaaaataaac aaaatgagtg atgtatatta ttcagaaaat catgaacaag
     6841 ataatcttta tgagcaagat aatttactgg cacaaagatt taatttattt actctattga
     6901 agtttgcatt tcctactatt tttatgatga tttttatggg gttgtataca atcgtagata
     6961 ctatatttgt atcaagattt attaatacaa atgctctatc agcaattaat attgtatgtc
     7021 caattattaa tcttatagtt ggaattggaa ctatgcttgc cactggagga agtgctattg
     7081 tagcacgtaa gatgggaaat ggtgatattg agggagcaaa taaagctttt tctttaatcg
     7141 tattatcagg agttgtaatt ggggtaataa ttactggtat aggtattgta tttatggatt
     7201 atatcattat atggttagga gcaagtgaag ttttaattaa atattgtcgt tcatatcttt
     7261 ttattatctt ggtttttgct tctgcaaata tactacaagt attatttcaa tgtttatttg
     7321 taacagctgg aaagcctcaa tttggattat ggctagtgtt aggtgctggg tgtgctaata
     7381 taattcttga ctatgtgttc attgttctgt tacaaatggg tattagtgga gcagcacttg
     7441 caactggagt aggataccta attcctaccg tttcaggtat ggttttcttt tcaaaaaata
     7501 aagggttact taaattttgt atacctagac tagataaaag aatattattt gaagcttgtt
     7561 ttaatggttc atctgaaatg gtgggtcaac tatcaacagc agttactact tttttattta
     7621 atgctatgat gatgaaatta attggtgaag atggggttgc agctattaca ataattattt
     7681 attctcaatt tcttttaact tcgctttata taggtttctc aatgggtgtt gcaccaataa
     7741 taagttataa ctatggaagt gaaaataata cgcagttaaa tcatgttttt aagatttgta
     7801 tattatttat ttcagtagca tctttattgg tatttatctt ttctatatca tgttcaccaa
     7861 tcattgtaga gattttttct caaagaggaa gccgagttta tgaaattgca aggtccggat
     7921 tttatatatt ttcttttagt tttatttttt gtggatataa tatttttacc tcatctatgt
     7981 ttacagcatt atcaaatgga aaggtgtctg caatattatc ttttctacgt acatttggat
     8041 ttataactat aggtttattg atattgccaa atatattaaa tataaatggg atatggttag
     8101 cagtaccaag tgctgagatt ttaaccttat ttttaaccgt tttttgtata tttaagtata
     8161 agaatagata taaatatatg tagatattaa ataaatagct tagatagata ttttatgttt
     8221 taataagtaa ttcaattagt ggtagatata tactattgaa aattaaagtt ataattgata
     8281 taaagaatta ataaaaataa catataaaag tttaaaaggg agttgaactt aaagtttgat
     8341 tagaaaaagt caattttaag acaactcctt ttattttact attgtattaa tctgtatctg
     8401 taagtgtatt agtctaatat tataaacttt ggatgaaatt aattttctat aggttttaat
     8461 gtatcataca ctttatttta aagaaactta tcttaatttt catagtgatt gaatttgtct
     8521 attagagatg ttactattag taatgtaaaa gcaatagtag tgaatataaa aaaacaagat
     8581 agtgatactg caagattaga atataataaa tttttatgga gagatttcaa tatggataca
     8641 tgttttaata aaaaaatatt acttgttgat gatgaaaaag atatagtaga tttaattgaa
     8701 gaagtactca taaatgatgg ttttaaaaac attattaaag cttataatgg tttagatgct
     8761 atttcgctgt gtaagatagc atgtccagat gttgtcattc ttgatataat gttaccagat
     8821 atagatggta tagaagtgtg taaaaaaatt cgagagtttt catactgttc tattcttttt
     8881 ttatcatcaa aaaatgatga tattgacaaa atactaggtc ttagtagtgg gggagatgac
     8941 tatataacaa agccattcag tccaagagaa attgcttttc gagttaaagc gcaattacgt
     9001 agacaacagt atcaaagcat tgtaccatca gatagtgaag ttattaaaat aggagatatt
     9061 actattgata tagaaggaaa ccgtgtatat aaagatagaa atgagattga gttaactgga
     9121 agggagtatc atcttttaag ctacatggct caaaatgtaa ataaaattat aggaaaagaa
     9181 agactctatg aacaagtatg gggagtatat agtagtattt gtgacaatac aattatggtg
     9241 catatacgac atataagaga aaaaattgaa gataacccct caaatcctaa aatacttata
     9301 acagttaaag gactaggata taaacttgtg aatagaatcg attagaatag attttaatat
     9361 taatgaagat atctcaagtt gaatttttag ttaatgaggc attcttttat gggtaaaatc
     9421 aaatgtattt tcgttatctc aacaatgaag aagaggtcta tctctatttt gagatagcct
     9481 cattaagttt atatcctggt aatgtacttt atgttctaat aaaatttttt tagtttattt
     9541 gcagtgaaac attaactaga acattaaaat ttgcgttgaa ataccaatta aataatattg
     9601 tatattgtgt ataaacttat actaattgtt tttctatatt aaatatttta tcaacccaac
     9661 ctttataaaa tttttcttca tgggaaacta ggattatact tcctctaaac tgtttcaaag
     9721 cattttgtaa agcatccttt gtctctgcat caaagtgatt ggttggttca tccagaataa
     9781 gaaaattaca aggagataac atcatacaac ataatttaac tttagattgt tcaccaccac
     9841 ttaaagtaga tacactcctt gaaacatgct cttccttcac accacatctg gctagatgac
     9901 gtctaatctc ttttgtattt aattttggat atttatctgc tactatttga agtggggttt
     9961 tatcaggatt ttcccatttt aaatcttgct cataataacc aattttaact tgttctgaaa
    10021 actggaaatc tccagatata cgaggaatat ctttgactaa tgtctttaac aaggtagatt
    10081 taccgattcc attaaaacca gttataacta ttttttgacc tccatcaaca gaaaaattta
    10141 attttggaag taaagaatag tagtatccaa cttcaagatt tgttatagta agagcatttt
    10201 gagccgatat ttcaatttct gaaaattgaa tatttggttt tcctgtaaaa ctaggaggag
    10261 ctattctttc tattttatcc aattgttttc gtcttcctct tgcaattttt gaatttactc
    10321 cagctttatt tttacgtata aatgtttctt ctttttctat tttcttttgt tgtgcttgat
    10381 accttctaat ataatcttct cttaaacgtg atttttgttt aaggaactct gaatattttc
    10441 catgatattt cttaatcatg ccaaattcta tatcaagaat acctgtagaa attttttcta
    10501 aaaaatcaaa atcgtgggaa actacaataa atgccccatt aaatgtattt aaataatttg
    10561 agagccattc aacatgttct ttatctaaaa agtttgttgg ttcgtctaat aatagaacat
    10621 catggttaga aagtagtaat tttgctaaaa ttacctttgc cctttgacca ccactaagct
    10681 ctctaacaac acgattcatt cctattgaat ctaatccaag accatttgct attttattta
    10741 tttcattatc tatagaatag aaattatttg ctattagttg ttcctgataa tctgatgctt
    10801 tgattagata ttgctcattt tcagatatag cacttttttg atagagtaaa ttcatttcct
    10861 tttctatttt ataaagttcc tcaaatgcag tgtgtaaata gagtgatatt gttgtatctc
    10921 tattgatttc tgcatattgg tctaaatggc ctatattgat attaggttgc cacttgattt
    10981 ctcctgaatc tggaacaact tctcccaata aaattttaat taatgtactt ttacctgtac
    11041 cattttggcc aactacacct atatgttcac ctttgaataa atcaaagtta gctttctcat
    11101 acagtgattt atccataaaa cattgtgata aattagttac ttttaataaa ctcataattc
    11161 aaactccttt tcttttatta aaaaatttat ggaaataaaa aaagcagagg aatggcattg
    11221 taaaatgccg acctctgctt ttggaaaaac aaaaggtcat agacaagcat tgttgtctat
    11281 gaccagaaaa tctatattat ctatcggcaa ataggtaatt ttaaataagc atagccaaaa
    11341 aactatacta aacctatatt tgccgatgaa gatagaaagc tttaagcttt cagattaacc
    11401 tctacacaac gcttcatcgt atacatttgt gtagagttaa gttttctaac aagtttaact
    11461 aattctatat aaatcataat tattcacatc ctaatcttag tattaattct agtttatcta
    11521 tatttaaatt gtacttttgt actttgtgga ttatcttatt tatttaaaat atgttttatt
    11581 aattatagct taagttatgt tatcataata cttagttata gtcaataaga aagttatatt
    11641 tactattatt atattaattt agtaaatcta tcattacaaa gttatttgaa gactcgctat
    11701 caataaaatt ttatagtcta taagaaaatt aagattatga gttttataat tttgatatag
    11761 ggatactatt ttcataaata ttacaacatg tagaagtata tgtctattat tgttgaattt
    11821 tcaatgatat attaaggttc taatatatta tacaaaataa aaacattaat tcaacttaaa
    11881 taattttaag tattatatgt gttttgatta aagaaaacta aaattttaag gaaaaataac
    11941 atatttgtat taaattttat tgaaatgatt aaatttattt acttaatgta aattattagc
    12001 taaaattgta ttaaataatt aaggaggtga gtagctctgg atgaaataga tttaaaaata
    12061 attaattctc taaaaaagaa tagtagggct tcaacctctg aaataagcag acaaattaat
    12121 ttatcagtac cagcagtctc agagcgtata aggaaaattg agcagtcaaa tttaattcaa
    12181 aagtacacta ttcaaattaa tcgggaaaaa acaaaatata agcttttggc ttttatattt
    12241 atcaatactg atttatctaa aagtatgaaa gaatttaaga aaactatatt ggaatatgat
    12301 actgtattag aatgtcatca tatttcagga gagtatgatt acttaataaa agtattagca
    12361 gaagatacaa gtagtcttga agagtttata tcagtgactt tgaaggaaat tggggggatt
    12421 caaaaagcta atacaaccat tgttttatct acaattaaag aagaatttaa tacaataaaa
    12481 gatatttttt aaataattta ctagtaaagt gttaattata ttttaggagg aaaatagaat
    12541 atgaaagttt tagttttttt agcaaaaggt tttgaaacta tggaatttag tgtatttgta
    12601 gatgttatgg gatgggctcg taacgattat gggcatgata ttgatgtagt gacttgtgga
    12661 tttaaaaaac aagttatgag tacatttaat atacaagtat tagttgataa gacgatagaa
    12721 gaagtatgtg ttgatgatta tgatgctcta gctattcctg gaggatttga agaatttgga
    12781 ttttatgatg aagcatatga ttcatctttt ttaaatctaa taagggagtt taattcaaaa
    12841 gaaaaaataa tcgcttctat ttgtgtggca gcattgccag ttggaaaaag tggtgtttta
    12901 aaaaatcgta aagctactac atatcatttg aaaaatggta aaagacaaag acagttaagt
    12961 gagtttgatg taaatgtagt taatgaacca attgttgtag ataaaaatat tataacctca
    13021 tattgtccag aaacagctcc acatgtagct tttaagcttt tagaaatgtt gacatctaaa
    13081 gaacaaatgg atgaagttaa attagcaatg ggatttaaac tgtaatggtt tatagatttt
    13141 ctaagtaatc agaaccccag tcacacatgg aatctaaaat tggaataata ctctttccaa
    13201 aatcagatag cgagtattct acttttggag gaacaacagg ataaaccact cttataatta
    13261 aaccatctga ttctaattca cgtaattgtt gagttaacat cttaggcgtt gctttaggaa
    13321 ttaatttttt taattcattg aacctcaata tagtgtcttt aagatgccaa agtataagtg
    13381 tcttatattt accaccaatc aatgcaagtg ttgcttctat tgggcaactg taattatcta
    13441 aacatttttt catttttggg ctcctttatt tattttaaag tatcttttta ggtactatat
    13501 tacaaaaaag tgcattattg taatatagta ccatagtgat aaaattatag cataggttaa
    13561 ataaatcatc aacttagcct aataaaacaa tagggggtaa ataaatgaat ttcgttgaac
    13621 ttgcaaaaaa aagatattct tgccgtaatt atcaagatag aaaggttgaa aaagaaaaac
    13681 ttgagaaggt tttagatgtt gcaagaatag ctccaactgg tggtaatcgt caacctcaaa
    13741 gattgattgt tattcaggaa aaagaaggta taaataaact ttctaaggct gccaatatat
    13801 atgatgcgcc attagcaatt cttgtatgtg gagataaaga caaagtttgg acaagacctt
    13861 ttgatgggaa acaacttaca gatattgaca caagtatagt tacagaccat atgatgttac
    13921 aggcaactga acttggattg gcaagtgttt gggtgtgcta ttttaatcca gatataatta
    13981 gagaagagtt tagtttgcca gataatctag aaccaataaa tatattattg atgggatatg
    14041 aatctaagat accagagagc ccagagagac atgaaaaaac tcgtgttcct ttaagtgaaa
    14101 ttgtttctta tgaaactctt taattataaa attaagttat tcataggata aatgtaataa
    14161 agtgtttatt ataaacaaaa ttcaaaataa ataatatcta catataatta attttagtga
    14221 agtatatcta gtttaactag aatgtatact tcactaattt atttattcaa aatatttatg
    14281 aggattttaa tatattaact aaaatatatc aattgaatta acttttaaat ctggaaaagc
    14341 acttgaaata tagtgtttta tgtcatttaa atggtcttga atttgctttt ctgatatttt
    14401 atcaggtcca tatacaaaat acataatatt tttagtatct tttgttatag ctgttcgatt
    14461 atcagggcca ttaagaatac tagataatat accaatatta tctgataaaa ataaatcatc
    14521 ttttgttaaa atatgttctt taccacctat accataaaaa tgttcacttc catttgctaa
    14581 ttctattttc aaaggtaatt ccattttatc aaggtcatga cctgctgtta gaagaagatt
    14641 tttcaattct gctaaaaaca ttgactcaat tgttacacct acatctggga taccttttga
    14701 ttttaataga atagattcta attgaagcaa tacagggtaa gttttcttga attttttata
    14761 atactttata taacttgaaa caggctctgt tttaattttt tctttacgat tgtattctgg
    14821 gtgttgttct ataatatttt taattgtaga gtttttaaga actaaaaaat tttctttatt
    14881 aggttttgaa tgtgtaatat ttataaccat aactccaaat ttaatattgg gataaatttc
    14941 tttaacttta tgtgatattt ctaacataat atagactcct ttttatttta tattttatga
    15001 tataatctta gcaaattaaa agtggatttt gtagttccat ttttatagta attttataga
    15061 accacttttg gaggtattag aatgtggatt acgattaata gaaatagtaa tatatcatta
    15121 tcaagacaaa tttattgtga gataaaagat atgattctgg atggaagctt aaagtttgag
    15181 caaaaactgc catcatctag gactttatca aaagaactat ctgtatctcg taatacagtt
    15241 ttagatgcat ataatcaatt aattgcagaa ggatatttgg aaacaaggaa tggatatgga
    15301 acaattgtag ctaaaggaat atcagggcat aaagttgatt ttaagttaaa tgatactttt
    15361 agagatgaaa aagatttaca tactaataaa caaaaaaatt atatagattt tcgttcagga
    15421 gttccagaat taaaactatt tccacgcaaa gaactttcaa agctatataa acaaatactg
    15481 tatgatttat cagattcgga tttcagatat ggaagtacag ctggtgtatg ggttttaaga
    15541 gtggaaatat ctaagtattt atttcgtact agaggaatta gatgtaatcc caaaaacatt
    15601 atgattgttt ctggttcaac acaaggttta tctttaattt cacagctttt atacaaaagt
    15661 aataaaaagg ttgctgtaga agaccctatt cataaaggct tattaaaggt tatttcatct
    15721 attggatatt cagttgttgg aattaaagta gatgataagg gaatgaatac caacttaata
    15781 aaatcaataa aggggatttc ttttgtttat actacacctt ctcatcaata cccattagga
    15841 gggattttac ctattcaaag aagactagag cttattaaat gtgcaacaga gaatgattac
    15901 tatataattg aagatgatta tgatagtgaa tttagatatg agggtcaacc aattagttct
    15961 ctttatgaac ttagcccaaa taaagtaatt tacataggtt cttttagtaa aatattatct
    16021 ccagctattc gtgttggatt tatgttatta ccagacaata ttttagaaag ctataaaaca
    16081 ttaaaaatgt actctgatgt tcatacagaa acaatattgc aacatgtatt agctggattt
    16141 attggaaatg gaggtttaga gaagtacata tttagaatga agaagttgta caatagaaaa
    16201 cgtaagtacc tcataaaagt tttaaacacg gaatttaaaa atgaatttaa aataaaaggt
    16261 gaagcagcag ggcttcatat agttgctcat ttctataatg ttaaatttac ggaaagttta
    16321 attcataaaa tttttgaagc aggtataaaa gtttatccta tacaacaata tgcaattgag
    16381 aatatattag aatatgacca tgaaattata ctaggttatg ctcatcttag ttttgatgaa
    16441 attgaaaaag gtgtaaaaat actcagcaaa ataatacata tgaatcaagg tacatagata
    16501 aaacatgtag caatctacat ataatagatg taattaagtt taaactttaa aagaaatata
    16561 tattaatatt tttgtataaa aatacctgat atttttttat cgatacttta ttgctataca
    16621 ctaaattaag atagcaattt atattaagaa aaaacttttt gcataggtta taatacttaa
    16681 aaggagagga tagagttgaa aacaaataca gatgttatta tggagataat tgattatata
    16741 gaagaaaatc ttacagaaaa tctaaattta gataaaatag cttatattgc taattattca
    16801 aaataccatt tacacagaat gtttacaaat gttgtaggat gtactatcca tcaatacata
    16861 cagaggagga gacttactga agcagctaga caacttatat ttacagacaa atatattata
    16921 gacatagcta ttacagtagg atattctaca catcaatctt ttacactagc atttagaaat
    16981 ttatataaag aatctccaca agtatataga aataaagatg aattttatcc tattcaacag
    17041 agatttgttt taaatctaaa tcatcaaatt caaagcgaaa aatgtatttc ttatgcaaat
    17101 atgaattata aacaaagaag agatgaaatc aattcttatc tgaactttaa tattaattgt
    17161 gaggtgaaag tagcatgagt ttagtgccac atgtaattga acaaacaggt caaggggaaa
    17221 ggtcttatga tatatattca aaattattaa aagatagaat tatatttata ggagaagaaa
    17281 ttaatgatgc tattgcaagt ttagtagtag ctcaattact gtttttagaa tcagaagacc
    17341 cagattcaga tataattata tatataaata gccctggtgg ctctgctaca tcaggatttg
    17401 ctatatatga tactatgaat tatgtcagat gtgatgtatc gactatttgt attggtatgg
    17461 ctgcaagcat gagtgctttt ttacttgcag gaggaacaca tggaaaaaga tgtgctttac
    17521 ccaattcaga gattatgatt catcagccaa tgggaggagc taaaggtcaa gcaacagatg
    17581 taaaaatagc tgtagataat atattgaaaa taaaagaacg attagataaa attctttctg
    17641 aaaatacagg taaatcaata gaagatatta ggagagatac agatagagat aattttatga
    17701 ctgcactaga ggctaaagag tacgggctga ttgattatat aatgaatagg aatgaataaa
    17761 gtatcaaagt atcatattaa aatatctgtt ttacaaatat atatataata ttaaataaga
    17821 gtgtctcaaa atgaactttt tagtttatgg gacactcttt tttgtatgaa attaaatatg
    17881 gttttatcat ttcaacaatt attaccaaat ttcaagttta ataaattcta ctataaaaaa
    17941 tacataaaag ataaggttct ttagtaactt tctgtcgtca aaagttttta taaatttaat
    18001 aacaaaacaa gagaaaatac catatattac ttatgtctgc aatatataga agacaaagga
    18061 gttgtacatt atgattacaa taagtttgtg catgattgtt aagaatgagg aagaagttat
    18121 aggcagatgc ttagaatgtg taaaggatat agtagacgaa attataattg tagataccgg
    18181 ttctacagat tccacaaaag aaatagtctc aaaatataca gacatggtgt acgatttcga
    18241 atggatagat gatttctctg ctgcaagaaa tttttcattt tctaaagctt ctaaagacta
    18301 tactatgtgg cttgatgcag atgacataat tttagaagct gatagagaaa aattattaaa
    18361 gattaaagaa agcttggata cttccattga tattgttatg gcaaaataca atgtatcctt
    18421 tgatgaaaat ggtgacccaa ctctctcgta ttatagagaa cgattgttta aaagaagttc
    18481 taatcataaa tgggttgacc ctattcatga agtagtacct ctttttggag aggtatttta
    18541 ttctgacatt gcaatatctc ataaaaagct tcatagacag gaccctctaa gaaatcttag
    18601 aatttttgaa aaaatgattt cagaaggaaa aacattggag ccaagacacc aattctatta
    18661 ttctagagag ttgtactata atgctaggta taaagaagca atagaaggtt ttactaagtt
    18721 tttagactca tcaagaggat ggattgagga ttgtatcagt gcttgcagag atttagccac
    18781 atgttattac ttaattaatg atgaaaaaag tgccttatat tcattgttta gaagtttcga
    18841 atttgatgag ccaagagcag aaatttgttg tgacatagga aagcatatgt ttgatagaca
    18901 aaaatataaa gaagccattt tttggtataa ggtagcatta acaagagata agaatgatac
    18961 taatggaggt tttaagtcaa atgattgtta tggatatata ccatctatac aattaagtgt
    19021 ctgttatgac aggttaggag aatcagataa agctatttat tatcatgaaa aaacaaaaga
    19081 aatcaaacct aacgatagtg ctgttttgca caatgaaaat tattttagta aatttaaaaa
    19141 tagttgatag gtcacaatca tactaaattt gacatattat atatagagct taaaagctca
    19201 aatatatcag gaggtgcttt taataatgag tagaaataaa tattttggac catttgatga
    19261 taatgattac aacaatggct atgataaata tgatgattgt aacaatggtc gtgatgatta
    19321 taatagctgt gattgccatc attgctgtcc accatcatgt gtaggtccaa caggcccaat
    19381 gggtccaaga ggtagaaccg gcccaacagg tccaacgggt ccaacaggtc caggagtagg
    19441 ggcaacaggc ccaacaggac caaccggtcc gactggtcca acaggaaata cagggaatac
    19501 aggagcaaca ggattaagag gtccaacagg agcaacaggg gcaacaggcc caacaggagc
    19561 gacaggagct atagggtttg gagtaacagg tccaacaggc ccaacaggag cgacaggagc
    19621 aacaggagca gatggagtaa caggtccaac aggtccaacg ggagcaacag gagcagatgg
    19681 aataacaggt ccaacaggag caacaggggc aacaggattt ggagtaacag gtccaacagg
    19741 cccaacagga gcaacaggag taggagtaac aggagcaaca ggattaatag gtccaacagg
    19801 agcgacagga acacctggag caacaggtcc aacaggggca ataggagcaa caggaatagg
    19861 aataacaggt ccaacaggag caacaggagc aacaggggca gatggagcaa caggagtaac
    19921 aggcccaaca ggcccaacag gggcaacagg agcagatgga gtaacaggcc caacaggagc
    19981 aacaggagca acaggatttg gagtgacagg cccaacaggt ccaaccggag caacaggaat
    20041 aggaataaca ggagcaacag ggttaatagg tccaaccgga gcaacgggag caaccggagc
    20101 aacaggccca acaggagtaa caggagcaac aggagcagca ggattaatag gaccaaccgg
    20161 ggcaacagga gcaacaggag cagatggagc aaccggagcg acaggggcaa ccggagcaac
    20221 aggtccaaca ggagcagatg gattagtagg tccaacagga gcaacaggag caacaggagc
    20281 agatggatta gtaggcccaa caggtccaac aggggcaaca ggagtaggaa taacaggagc
    20341 aacaggagca acaggagcga caggtccaac aggagcagat ggattagtag gtccaacagg
    20401 agcgacggga gcaacaggag cagatggagt agcaggtcca acaggagcaa caggggcaac
    20461 aggaaataca ggagcagatg gagcaacagg tccaacaggg gcaacaggtc caacaggagc
    20521 agacggatta gtaggtccaa caggagcaac aggagcaaca ggattagcag gagcaacagg
    20581 agcaacaggc ccaataggag caacaggtcc aacaggagca gatggagcaa caggggcaac
    20641 aggagcaaca ggtccaacag gggcagatgg gttagtaggt ccaacaggag caacaggagc
    20701 aacaggagcg accggagcaa caggtccaac cggagcaaca ggtccaacag gcccaacagg
    20761 tgctagtgca ataatacctt ttgcatcagg tataccacta tcacttacaa ctatagctgg
    20821 aggattagta ggtacaccag gttttgttgg ctttggtagt tcagctccag gattaagtat
    20881 agttggtgga gtaatagacc ttacaaacgc agcaggaaca ttgactaact ttgcattttc
    20941 aatgccaaga gctggaacaa taacatctat ttcagcatac ttcagtacaa cagcagcact
    21001 ttcacttgtt ggctcaacag ttacaattac agcaacactt taccaatcta ctgcaccaaa
    21061 taactcattt acagctgtac caggagcgac agttacacta gctccaccac ttacaggaat
    21121 attatcagtt ggttcaattt ctagtggaat tgtaacagga ttaaatatag cagcaacagc
    21181 agaaactcga ttcttactag tatttactgc aacagcttca ggtctttcat tagttaatac
    21241 tgtagcagga tatgcaagtg caggaattgc aataaattag attaaataag aaaaggcttc
    21301 taatatcgta ttgatattag gagctttttt aagaatgatt gatgaacata gttttaatat
    21361 taattagtgc gcatattata aaatactatt atataatata aaataataac attaaattgg
    21421 aaatatagaa ttatctaggg gtgatactat gaaaaataag attgaaatat caatgaacaa
    21481 ctttgtaaaa aattatcata aatcaaataa tataactaca aagtggcaag aacttttgtt
    21541 tgcttatgca tctgctgaag atgatatgtt tcagaagcta aaaagtgttg taggaacatc
    21601 tcatgctatg ccaaaagatt ttctggaaaa tggaaaaact ataattacat attttatacc
    21661 ttttgatgaa agtgtaaata atagtaatat tggagggttt gaatgttctg aaatatgggc
    21721 aagagcgtac atagaaacta atatgttgat ttcaaattta aatgatttct tatgtgaaga
    21781 actagagaag atgggggcta attcatatgc tattcctggg tcgtataatt ttgacagtga
    21841 aaaattggta agtgactggt cacaaagaca tgtagcattc atagcaggtc ttggaacttt
    21901 tggtttaaat aatatgctta ttacagaaaa agggtgttgt ggaagaatag gaagcataat
    21961 cacaagttta gaattagagc caactaaaag accagaaaat gaatactgct tgtataaaca
    22021 taataatagt tgcaaaaaat gtgtcaacaa atgcgtgaaa gaagctttaa aagaagatgg
    22081 atttaatagg aataagtgtt atgaaatgtg tatgataaat gaaaaaaaat acacttatat
    22141 aggtggatgt gatatttgtg gaaagtgtat agttggagtt ccttgttcag taataaatcc
    22201 atcaagataa tggacttaag ttgactaata attttaaaga tagtttataa tgaaaaaatt
    22261 ttagttatca aaataaatat aatataaaaa ctaaataaat gtgtttaaaa aatggataaa
    22321 taatttatgt tgattgacaa ccagttatac tgttgataga cttatatgta tcgctgtgat
    22381 atataaggag ggttgagatt ttatgtttga tttaatcttt atttttgcat agcaagggct
    22441 attgcaacta tgaaatttaa tatataaata gccctttgct attcctaatg aaaaattact
    22501 atttaatagg agagcaaaat gagctataaa aaagcaatac atatattacc agaagaatta
    22561 cttgaattaa tacaggaata tgtagatggt gaatgtatct atattcctag aaaatctaat
    22621 aataaaaaag aatggggaag taatacacct actcgtgaag agttgtcaat tagaaatatg
    22681 cagatttacg aagactatca agttggatat gatttgcaat atttatcgga aaagtattat
    22741 ttatctttga aaagtatcca aagaattgta ttacaagaaa aaagaaaaga tatctaagga
    22801 tgagccagta tagttttata attatactgg ctcattttct tttgataaaa gtgtttgagg
    22861 tatagtttct tttaagtgga tgatataatt taagtaattt caataactta tacagtagct
    22921 aacaaagctg gttgtaaagt atctaataag aagtagtagc tttttatatg tttgaaatta
    22981 aaatttatta aaattaggag gtcttgtttt gaaaaaaata cttgattata ttccaccttt
    23041 tcataacttt ctattaattt agtaatctta tagaaaggaa attgcattta tgaaaaaaat
    23101 tacttgggag gtggaatata tctcccagtt acctgtaatt aggtattgta aaaaatgtgg
    23161 aaaaaagact gaatatattt gttcaggttt atttagggtt aatgctcaac ataaatattt
    23221 ggatatatgg ttaatataca agtgttcaaa ttgtgattca acatggaact caactatata
    23281 ttctcgtgtt aatccaaaaa gcttaaatcc agaaatacta gaacaattcc atacaaacga
    23341 ttataatctt gttaagcaat atgctatgaa tatggaactt ttacatagaa atggagcaga
    23401 agttggtatt ccagagtata aaatagtagg acaagaaatt aatattaatg accttacaca
    23461 agttcatatt attagtaaat atccatgtca gttaaaggta tcaacattat tacgtgagaa
    23521 actaggttta tctaggaagg tatttgacga aatgttggat tgtgggatta ttagaagtaa
    23581 ctcaggagtt gatttaaaga aaggtaaatt aaattatgaa attatgttag atataggcaa
    23641 ggagaagcaa aagtcttcaa attgattaga ataactaact taatatattt tcaggaacat
    23701 catttaaaaa aatagtgact ttaaaaaatt taaagccact attttttaat atgttttata
    23761 tgagtattta aaataaagtg tgtattcttc aaatttatag cgataattaa aacattacta
    23821 taaaaaggaa ggtgcatact ttttatttaa caaaaactag atattaaaaa cttttcgagg
    23881 aatattttat taaaatccct aaatatattt aatatatgtt aaaaaattgt attataatga
    23941 aaatcaaaat agattgcaaa tccaaaaagt aatacttaat gtccaaaaag ctaaaattaa
    24001 aatctaaata gctatttact acagaagtat gttaaaatat gtaaaatgaa tagaaattta
    24061 tatattttta ttaaaaatat ataagaaagg atgtttaaga attgtgatta atataggaat
    24121 atgtgatgat gaactacatt atcgaataaa aataaaagat atattaagtg aaatattaag
    24181 ttcatatcct ataaattata acatatatga attttcagca ggagaagagt tactaaataa
    24241 ctatcctaaa gatttagaca tattaattat ggacatacaa atgaaaacaa taaatggtat
    24301 ggatactgct aggaagataa gagagtttga tcataagtta gaaataatat ttgttacttc
    24361 atttgtagag tttatgcaag aaggttatga ggtaaaagca tacagatata tactaaagcc
    24421 aataaataaa gaaaaaattt ctaaaagtgt attaccttgt ataaatgaga tgatgaaaaa
    24481 gagaaataat tacttaacta taaatgtaaa aaattatgta gaccgaatta aaatagattc
    24541 tattacttat atagaaacag atagaccgaa tatattgatt tatacacatg atgatatgta
    24601 tattactaaa atgagtatat ctaaaataga aaagatatta aatgaatatg gattttttag
    24661 atgtcataat agctatatag ttaacttaaa attagtagaa tcaatgagtg gaagtactgt
    24721 tatagtagat ggaaaaagta ttccaataag taaatatagg gttaaaggct tgaagcttgc
    24781 gataactaat atattagggg acatagtatg ctaacaaatt taagtgtagg attttggaat
    24841 attattaatt tagtttcagg tactatagat tggattatat tttttttagt aatccactta
    24901 gttggaaaga ggaaaatatc taatataaga tatatattta caacaataat tataattata
    24961 tttatggcat acataaatgt agttaaagtg tttccaaata ttaagattct tctatgtatg
    25021 gtaataggaa tatcatttta tataacatca tatgaagata aaatctataa aagtataata
    25081 gttagtttat tgttttggct aggattaatg gttgctgaag gttctgcagt aggtctagta
    25141 gtatttataa ataaattaaa taatattaac ataacacaac atgaaaactt atttagaata
    25201 caagctatta ttatgtcaaa ggtattttta tttataggtt ttatattgtt taagtatttt
    25261 aaattatctt tagattttaa acctaaagat atgatactaa taggaatacc tatattatct
    25321 aatatagtta gcttattact tatatttgaa tataatttaa gagtcaatac aattactaca
    25381 gaaaacttat ttatatttat atttgcaatt ttattgattt tatcatcaag tataatactt
    25441 ttaatagtaa tagggaaaat tgtacaagac gataaattaa atctagagta tgaacttata
    25501 aatgaaagaa taaaaacaaa ctacaggaat tatgaaaata taaacgaagt tcatgataga
    25561 ttaaaatatg tttatcatga cttgaaaaac catatgattt gtataaaaaa ttatgacact
    25621 aaagaagaaa ttatatcata tataaataac ttagagtttc agataagtga atttgaacat
    25681 tttaaaaata ctggaaataa aacattagat ttaattttag cagaaaaaat aagtatttgt
    25741 aaaaagtatg atattcaaat tgaagataac ataaatatat ctaaattaaa ctttattaaa
    25801 aataatgata tatgttcaat atttgcaaat tcactagata atgcaattga agcatgtatg
    25861 gatataaata atgagataga aaaaagaata gaagttaaag ctacatatat aaataaattt
    25921 gcaataataa aatttataaa tactaaggta aatgatatta aacttattga taaacgtatt
    25981 caaactagta aggatgatga taagatacat ggaataggac ttgctagtat taaatatata
    26041 gtaaataaat atggtggtga aacaatagtt aattactcag ataatgagtt tatattaaaa
    26101 ataatgatac caataaaaag ttaggagagt acaaaatgaa aaaaatagcg ttaaacttac
    26161 ttaaaaacat ctcagcatta agttttggga tagctgtatt atcagcaaac agtgcaagtt
    26221 cttgggtagc acatcaggca aaagagccag aagctttaca aaaactaaaa aaataacatt
    26281 aataaaagga cctcttctta ttaaaggaga ggttttacat gttgaggagg aaatatgttt
    26341 aaaagattat catataaatt tgccaatata ttagttaata atgagattgt agaaagtgaa
    26401 gattttgaaa tatatagata tggatttgaa actttgattt atttcatagt taatattttg
    26461 gtagcattat ttataggaat tatttttgat agatttatac atacagttat atttttaagt
    26521 tgttattgca ctttaagaca gttcacagga ggttatcatg ctaggaatta taaagagtgt
    26581 acattaacat ttgcagttat ttatttgata actatttttt cagctaataa tatagatata
    26641 aataaatata agtatttatt agtattatta atgattatta gtatactaac aatttacaag
    26701 ttagctcctt tagaacatag aaacaaacct cttagtgaaa gtgagaaaaa gcattataga
    26761 aagactgtgc aaaaaatact attcgtaata atatgtttaa ttattttatg taaaatactt
    26821 aatatttttc agcaatatgt gatttatgca ataatttcta tatattggat tgctatatta
    26881 atatatattg gaatgaaggt taatagtgat cagtaagatt ataaaacatt ttctaaatta
    26941 attaacttca ctaattaata ttaactttaa aaaaataatg tcaaggtaag tatttgaact
    27001 tattaaatat agttgaatct attgtgggtt gtatcaaagg acaaatagat tcacttaata
    27061 accagtttgt aacagagtat tgaattgtaa aagttaatac gatagtatga aaatgtaatt
    27121 tgaaattaca tttttataaa aattatatta actaagggga gagatacata caatgaattt
    27181 gaagaaaaaa attaaaaagt taggagttac atttgcaata ggaactataa ttgtatcaag
    27241 tttagggaca tctgtatttg cagatgaggt tagcacatat gctttaatat ctaaagcttt
    27301 ttcaggtaaa aacaatatta tatctagttc agtatacact tctggaagta gaacctttaa
    27361 aacgacagat tctcaagggg gattttcttg taggctaaca gaaagattct caggatctag
    27421 cccagataga attgtaaaaa gacatgaagc aaatgcttct tcaaaagtta gtttatcagg
    27481 aggaacatac tatataaggt atgaaggttc aacgaataat gctaaaacat atgcaacttt
    27541 aaattagtat taaaagcatc ctataattat ttttatagga tgtttttgta attgttataa
    27601 tcaaaagact ggctaggagg ggcataaata tgagtagtat taaggttata tcagacttta
    27661 taaccaaaat aattagaaaa aatattttat ttgcaataac agttattatt ataaattacc
    27721 atctcataca acgatggaca catatatcca atagaggaat ttcatttaat gattacttat
    27781 ccttgagtgt atatacttgt atgacaatta gtattttaac catgttaaat gtaatttttt
    27841 atatgagaaa aagttatgat actgtaaaaa tattatgtag aaataatttt gattattttt
    27901 taggtatttc tgttgctgta actagaaaca actttatatt ttgttgcata ccaattatat
    27961 atgctatagc atactcaagt ttaataagaa cattgtcaat tgtaacgatt aaatcaacta
    28021 tatttatatt gatatttgaa tggtttttac cacttactat tttatctata gtgatatcat
    28081 ttatttcagt tattataaat aatttaatac taaagattac cttatcatca gtatttttat
    28141 atttaacatc aactaatatg ttggatagag ttattgatat taaagaacca ttttttaaag
    28201 cattatttaa atcacttaac atatttgaag atcaatcata tgcttactat tctgattttg
    28261 tagggaaagt taataattca gcatatgtta tagataagat tatacctaca ctatttgcaa
    28321 ttactttaat aatagtagca tatctgatat taaatgatat tagaaagaaa cagattaaat
    28381 cattaatagt tatagtagtg tacagtattt tatttattgg attaaattat atatcaatag
    28441 atatgtcaac atatagagat gaggagcgta gttatggaga gtatttaaag aaatctaata
    28501 ttagtgatat taaaataaag tcgcatgata tgaagattga ctttaaaagc aagtcaaata
    28561 taaaagatag aattgtttta ttaaacacat caaatgaaga gttaacaaat attaatatga
    28621 ttttagatga aatatttgat ataaaatata taaaagtaaa ttcggaaaat ataaaattta
    28681 acataaaaaa ggatttaatt gaagttaatt taaaggaaag tttagagcct aatgacgagg
    28741 tgacattaga tatagagtat gaaggctata ttaatgtgtt gacatcttgg aatcaaaata
    28801 aatatatagc tactaaagat gatattatgc ttccaccagg ttctttagcg tggtacccaa
    28861 aagtaaatca atcaagttat atggcttata aaataaattt aagttctaaa aataatgtct
    28921 attcaaattt acctttactg aataagacta gtaatttttt aaaaaaagat tatatatttg
    28981 aaggaaagtc aaatgatatt gcaatatatg caggtgagtt taaagaagag gtaaaagatg
    29041 atataaaaat aatctatcca tcagatagta atgtaaatat ggatatagag gaaaaaatta
    29101 aatttttaat tgaaacaaga aatgaaatat taggtgatag caaagcatct gtagatgcta
    29161 aaaaatatgt agatgaagta gataatgtta tggaatcaat aaaaagaaaa aaaattaata
    29221 tgatattagt tgctgactta cctagcaatg aatttttata tgaagactca aagggagaga
    29281 aaattagcat aactatttat cattggcttt caggaaatat ccttataata gataaataat
    29341 aaaggaggtt aatatgataa acaagttaga aataagaaat ctaaatttta attacaaaaa
    29401 taaaaaagct ctggataata taaatttaac cctaacagat ggagtagttg cattattagg
    29461 tcctaatggt gctggaaaat caacattaat gaggttatta gtgactcttt atgaaacttc
    29521 aattggagag atagaattaa ataatataaa gtatagcaaa aacaatgaga aaatcaaggc
    29581 aaatgtagga tatgtacctc aagattttga tatgtataat aatataaatg ggcaagaata
    29641 cttagaattt gtagctaaaa tgagaggtgt atctaagaat gatttaaaga aacatataca
    29701 aaaagtagta tcaaaagtta atctggacaa gtttataaat aaaaaaatag gtacatactc
    29761 aggtggtgta aagagacgac taggtatagc acaggcttta ataggtgatt ctaagttaat
    29821 agttatggac gaacctacag ttggtcttga tccagagcaa aggaatgaat ttagaagatt
    29881 gttaccagaa ataagtaaaa attctatagt attaatttca actcacatag tagaagacat
    29941 acaatttaac tgtgacaaat taattatatt aaatcaaggc aaaatattat atgatggtac
    30001 aattaataag tttattgata tggttgaggt gtattcggta gtagtttcta atgatgaatt
    30061 tgaatattta gaacgtaata ttgatattat tgattatagg agagttaaag atggtgtgca
    30121 agtaaagtat ataggtaaaa atacagagaa acttaaagat agcttaagga tagatacaac
    30181 tttacaagat gcttatataa actttttaca taaggagtta aaataaatgt gtatattgga
    30241 gttaataaaa tttgagctta aaaaaataga gcttaaacat gtgttaatat ttgtaattat
    30301 ttctatatta tgcatattta ttacaggcat attagattat aatgagttaa tattttataa
    30361 tgatgtacct ataatggata catattctat agcaggatgg ttaggaatta taaagatatc
    30421 agatgttttt ataccaataa tgtcagcaat cacaataatt tatgtgtttt caaaagatta
    30481 ttcgggtaat ataaatgaga tacttacttt atataataaa aaaaaatata atcaatttat
    30541 agtatttaga tggtgtgtta tattagctat atatactgta ttattgttaa tttcaattac
    30601 aatagtatat acatttacgt cagtgaaagg ttttaacata gacaaaatag attttgttta
    30661 tagtgtaaag ccaatagatg tgtttttaaa gacgtttcct acattattat ggtatacaac
    30721 atttccacta atgatattaa cattaacaaa aaatagattt acaacaatag caatattaat
    30781 tacatataca tttgctgata tattttttat tttacatatg tacccatttg ttagtatgat
    30841 taatgtaaat ggattttata ttcaaaagat gttttatatg cctaacaata tagatgttag
    30901 atttaatgaa ttaaagaatt atttctttat aaatagaggt tctctagtag ttatttctat
    30961 aataatagtt ttttatatag caagaaaatc aacggtttta aaaaagagta aatagtttaa
    31021 tatatttttt atattgttat atttatatag aatagtgact ttaaaaaatt taaagccact
    31081 attttttaat atgttttatc tatataacta ttatttttct aggtttttta atatttcgta
    31141 atagtgtgtt gtggctattt cacttgactc gcctttttta caaaaagata atttagatag
    31201 ttttggaact acacgttcaa cgacaatttt attacctatc attttagatt caagtatctt
    31261 caatgcttct aaaaatctat tatccttttt tgcacgatta taaaatgata aaacgtagac
    31321 ataaaggaat aggttataat tacggaaagg atattcaact tgcataaata atgtgccaat
    31381 tccatagtga caagggccga ttggtttttt aatagtccaa tggtcaagta gaaaatctac
    31441 agctttgtca agttttgatt ctttatttag ataattacta aaacggaatg catttaatat
    31501 attaagagtt ggtagtggat ttgagtattc agtttctgga cctcgaccaa aactaaattt
    31561 attgcaacgc cacccaccat cagtatactg tgtatctaaa aaatgttgaa acgttttttg
    31621 cattctaatg tcagatgcat atcccatatg acagagtacg ttagcagcat ttgcagtatg
    31681 acaagggtaa atacctccat ttggatatag tttgaaacgt ccatcttctc gccatgtgct
    31741 aaatatcagg tcagcacatt ctttaagtaa agtatcatca gggttcacac ctaattctaa
    31801 tagataaagt acactatcaa gagtagagaa aggagaacct tttattaaac gcttatcagg
    31861 tgtagtccaa tagtctgcac cattatcata cctgtgtgat aatattattt caatatctga
    31921 taaagattga ttttctacat tcatttttta ctccatttca tattatattc tattaaatct
    31981 atcaaaaact ttattataat attatttata tttataattg atttatttta tttaaaattg
    32041 catctatagc tgtatcagga acaactgcta aatcttctgc attgaagtaa taaactatat
    32101 tagaatcaaa taatatattt gaatttggag gaaattcatc atctccaaac caaagtataa
    32161 ataccataga tgtattaccc atatatgtaa acctataagc taaatctccc atgtttactt
    32221 tttcagctcc aattttctcc ataactaact tatatttgtc tatttgagat gtaaaaactt
    32281 ctgaaagcct atatagagtc ctgtttaaaa aatttggata ataaacattg cctcctggta
    32341 tttctttaaa agttacatat ttattagttc taggaatacc tttagcattg attaaatatc
    32401 taactatcaa gattttaagc tcaaagttat tgcaaaggct accattacta ttccaaactt
    32461 ctccacttgg atagtctata atatattgtc tatcaaaaaa attgagtgtg aatctattta
    32521 aatcattatt gaaaggtata ttacttaaat tactaattgt atgagggtct aattctttga
    32581 gtttttttcg aacatagtca aatggaacat tataattatt ttttgtt
//
LOCUS       DAEQAF010000042        32261 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.043, whole genome shotgun sequence.
ACCESSION   DAEQAF010000042 DAEQAF010000000
VERSION     DAEQAF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32261
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.043"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            165..1511
                     /locus_tag="KRN00_002005"
     CDS             165..1511
                     /locus_tag="KRN00_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1827871.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESIFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKRHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     gene            1589..2983
                     /locus_tag="KRN00_002006"
     CDS             1589..2983
                     /locus_tag="KRN00_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBH1827872.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(3105..3779)
                     /gene="fsa"
                     /locus_tag="KRN00_002007"
     CDS             complement(3105..3779)
                     /gene="fsa"
                     /locus_tag="KRN00_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBH1827873.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            4053..4817
                     /locus_tag="KRN00_002008"
     CDS             4053..4817
                     /locus_tag="KRN00_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1827874.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLITNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            complement(5106..5327)
                     /locus_tag="KRN00_002009"
     CDS             complement(5106..5327)
                     /locus_tag="KRN00_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827875.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(5728..7005)
                     /locus_tag="KRN00_002010"
     CDS             complement(5728..7005)
                     /locus_tag="KRN00_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBH1827876.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            complement(6989..7657)
                     /locus_tag="KRN00_002011"
     CDS             complement(6989..7657)
                     /locus_tag="KRN00_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1827877.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            complement(7817..10318)
                     /locus_tag="KRN00_002012"
     CDS             complement(7817..10318)
                     /locus_tag="KRN00_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBH1827878.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            complement(10609..10800)
                     /locus_tag="KRN00_002013"
     CDS             complement(10609..10800)
                     /locus_tag="KRN00_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBH1827879.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(10948..11190)
                     /locus_tag="KRN00_002014"
     CDS             complement(10948..11190)
                     /locus_tag="KRN00_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827880.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            11402..13225
                     /gene="typA"
                     /locus_tag="KRN00_002015"
     CDS             11402..13225
                     /gene="typA"
                     /locus_tag="KRN00_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBH1827881.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(13315..14223)
                     /gene="trxB"
                     /locus_tag="KRN00_002016"
     CDS             complement(13315..14223)
                     /gene="trxB"
                     /locus_tag="KRN00_002016"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH1827882.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    15025..15256
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15364..16845
                     /locus_tag="KRN00_002017"
     CDS             15364..16845
                     /locus_tag="KRN00_002017"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBH1827883.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISNDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSEINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            16855..17748
                     /locus_tag="KRN00_002018"
     CDS             16855..17748
                     /locus_tag="KRN00_002018"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBH1827884.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPGKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            17872..18933
                     /locus_tag="KRN00_002019"
     CDS             17872..18933
                     /locus_tag="KRN00_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBH1827885.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(19088..19600)
                     /locus_tag="KRN00_002020"
     CDS             complement(19088..19600)
                     /locus_tag="KRN00_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBH1827886.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            20120..21055
                     /locus_tag="KRN00_002021"
     CDS             20120..21055
                     /locus_tag="KRN00_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBH1827887.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(21147..23018)
                     /locus_tag="KRN00_002022"
     CDS             complement(21147..23018)
                     /locus_tag="KRN00_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBH1827888.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYVSLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            23208..24134
                     /locus_tag="KRN00_002023"
     CDS             23208..24134
                     /locus_tag="KRN00_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH1827889.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIITAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            24273..24419
                     /locus_tag="KRN00_002024"
     CDS             24273..24419
                     /locus_tag="KRN00_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827890.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(24524..25048)
                     /locus_tag="KRN00_002025"
     CDS             complement(24524..25048)
                     /locus_tag="KRN00_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1827891.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(25101..25325)
                     /locus_tag="KRN00_002026"
     CDS             complement(25101..25325)
                     /locus_tag="KRN00_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827892.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            25522..26646
                     /locus_tag="KRN00_002027"
     CDS             25522..26646
                     /locus_tag="KRN00_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBH1827893.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNDTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGISDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(27120..27944)
                     /locus_tag="KRN00_002028"
     CDS             complement(27120..27944)
                     /locus_tag="KRN00_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827894.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(28291..29346)
                     /gene="ispG"
                     /locus_tag="KRN00_002029"
                     /gene_synonym="gcpE"
     CDS             complement(28291..29346)
                     /gene="ispG"
                     /locus_tag="KRN00_002029"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBH1827895.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(29529..30533)
                     /gene="rseP"
                     /locus_tag="KRN00_002030"
     CDS             complement(29529..30533)
                     /gene="rseP"
                     /locus_tag="KRN00_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBH1827896.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(30546..31700)
                     /locus_tag="KRN00_002031"
     CDS             complement(30546..31700)
                     /locus_tag="KRN00_002031"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBH1827897.1"
                     /translation="MKKISILGSTGSIGKQTLDVVRDNRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(31864..32067)
                     /locus_tag="KRN00_002032"
     CDS             complement(31864..32067)
                     /locus_tag="KRN00_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1827898.1"
                     /translation="MISYAPLWKLLIDKKIKKMEFVNISSISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
BASE COUNT        10871 a         5005 c         3854 g        12531 t
ORIGIN      
        1 gattatatta aatattgatt tattaaattc aaattataat tatattcttt acattttaaa
       61 aaaatatatg atattttgat acaatttatt tatagtttgg atataaagtt tatgttaaga
      121 ttatactata ataaattaat aattttttta tttggaggaa taaggtgaaa gatttaacta
      181 caggtcatga gggaaagtcc atattctttt ttgccatgcc tatgcttatt ggtagtttat
      241 ttcaacaact atacaataca gctgacagta taatagttgg tagatttatc ggaaaagaag
      301 caatggcggc agtctctgga gctaacccta taatgttttt attggtggca gcgcttatgg
      361 gtgttagcct tggattttct attttagtgt cacaatttta tggctcagga gatttaaaaa
      421 aggtaaaagc tactattgat actacatata tacttttatt tattggttct atattaataa
      481 gtattcttgg aatagtattt ggtggcccca tgcttaagct tatgaataca ccagaatcca
      541 tttttgctca atcaaaattg tatcttacta taatatttag tggaatatta ttttctgctg
      601 gatataattc agtaagtgca atacttagag gacttggaga ttcagtaact ccactttatt
      661 ttctgataat agccacaatt ctaaatatag ttttagactt aacttttatt gtagtgctaa
      721 gaatgggtgt tgagggcgtt gcacttgcca ctataatggc tcaggcagta tcatttataa
      781 taagtataat ttatttaaat aaaagacatg aagtgcttaa atttaaaatc aaaggaattg
      841 tatatgataa caaaatattt aaagatggac ttagattagg acttccaagt ggagttcaac
      901 aaatgttgtt ttcaattgga aatatggctc ttcaattttt agttaatagt tatggtacat
      961 ctgctatggc agcttttggt gctggtctta ggatagaaaa ttttataagc ttacctatta
     1021 tgaatcttgg ttctgctgtt tctacttttg ttgctcaaaa cataggtgct ggagaaaatg
     1081 aaagagttaa aaaaggcatt cgagaatcta taaaaatgac cttagtttta gcagttacag
     1141 ttattgcttt aattttgcta tttagggaaa atctaattgc tctattcaat actgataaag
     1201 atgtcattaa aattggctct tcttacttat ttataatagg accattcttt ttatttattg
     1261 gaacttcttt tgtactttca agtgcaatga aaggtgctgg tgattccatg tttgcactta
     1321 taagctcaat agtatcttta tggcttggaa gacttccagc ttcttatatg ctttctaaat
     1381 tttttggaac agacggaatt tggatgggta ttccttttgg ttggacttta ggtcttattg
     1441 ttacagttat ctactataag aaaggacatt ggaaaactaa agctattgta aatcatagaa
     1501 tcaatgaata atctttttat aaaatgtatt cacattcatt gtattcacct ccattatgat
     1561 ataataaatt atggaggtga atataaaaat gggtattatt cttaagccaa aacaatttta
     1621 tatgactgtt atagctacca taattctcta cttctctctt aattacagtt tcaacataaa
     1681 attttctata tgcttatctt ttttaactat cttgatatgg gctgtagact cagttgaaaa
     1741 aacttttgtt gcattgtttt ttgtaattct agcgtttata tttaacattg caccaataaa
     1801 ggttatttta cagtttttat ttacagaaaa tttttacata ataattcttg catacataat
     1861 tactaatgca gttacaaaaa caggtgtcgc aaaaattatt tctgagaagt taattttaaa
     1921 tactgtaaat acccctaaaa aaatgattct tttatcgtat attttaggta tacttttaat
     1981 attttttatc ccacaaccat ttccaagggt tattcttgta tctgcttttt acaaggagtt
     2041 tttaaaagaa caacagataa ctgaagattc aaaatctata cttttattta gtatatttac
     2101 agcatctacc tttacatcaa tgttttttgt aaatggagac actcttctaa attatgttgt
     2161 actagaactt ggaaattgta atataaattg gggtcaatgg gctttttata tgtctgttcc
     2221 aactataatt acttgtttta taacttattt tttatttatc tttgtcttta aaaaagaatt
     2281 gcattcaata aaatttattt ctaatgaaaa tcttgagggt aataaacttc atttttcata
     2341 ttctaattta aaaaaagaat ttaatttgct aaacaaagag caaaaacacg tatttttatg
     2401 cctaggaata atgtttttta tgtttttaac tcagttcata cataacataa acacattaat
     2461 tataatgtca atttgtgtac ttcttttatt actaagaaaa atagttggat ttagtacttt
     2521 aaaagaaata aattggaagg tccttatttt ttttatagca gcattttcaa ttggaggagt
     2581 gttaaagtac tctggagttg tagatataat gggaaattat ttgataaagt ttataccaaa
     2641 ctcttcagaa attatttcaa tattgttttt gataactctc acaataatct tgaatatatg
     2701 tcttggaagt gctgtcacta catcatctgt agtaatacca ttacttggaa gtttacatat
     2761 actaaaggaa aatagtgtta ctttatgtct atttgtctac attatagtaa gcatacagta
     2821 catattacca tttcatcatg ctacaataat ggttggtcat ggtgaaaatc tgtataatag
     2881 caaggttatt ttcaaatacg gtttaacttt gattccttta acctacttta taataatatg
     2941 tataacattc ccttggtgga aatttatagg actagaaatc taaaaaagat gaaaatatga
     3001 attaacttaa gataataacg aaattattaa aaagaaaatt catattttca tctttttata
     3061 taagttcttg tgaaattgga caaaactact cttttaccat aatactaaat attatttgtt
     3121 ttacttcctt ttccaaaagt attctcccaa tcctctataa acttatctac actccaatca
     3181 gttaatggat gattcatcat agatttacaa atatcatatg gtactgtaac actatgcacc
     3241 ccatgttgca ttaattctat aacttgttgt gcatttttaa aactggctgc aagtactttt
     3301 gtatccattt tataagtatc tattattttt ataagttctg aaaccatagc tactccatca
     3361 ccagatatat tatcaagcct atttacataa ggtgcaatat aatttgctcc agcctttgca
     3421 gctaaaaaac cttgatgagc agtgaatatt gcagtagcag ttatttttac accttttctg
     3481 tgaaggtctt ttatagctct taaaccatct tgtgttacag gtatttttac atatatattt
     3541 tttctcaaac tacttatata taatgcttct tctaatattt cttcatactt tgtacttaac
     3601 acttgagcat gtataggcat atcctcacct ataatctcac caatttcatt tataagttgc
     3661 ttaaaattct ttttttcttt tgaaacaata cttggatttg tagttacacc atctattggt
     3721 aaacaagtac ataactcctt aatctcctcc acattacctg tatctaagat tagttgcatt
     3781 aaaatatccc cctttaatct ttctttattc ttattatata ttgatttggt attattttca
     3841 acattttgct tattgttttt tattttttat tattgtttta cttttccttc ttagttttat
     3901 aattttttta tttactaaat tctaaatata tagttagaaa aaacatactt tttatattaa
     3961 attaattttg tatttcatgt taaaatagtt gatatattgt attttatctt ataatattta
     4021 ctataatact atattgcgaa aagaggtaga aaatgtttgc agaagaaaga atccaagcta
     4081 tattaaatat cctaaaaaaa gaaggtagag ttactgtcaa agagctcagt tctaaattta
     4141 atgttacaga agattgtata agaaaagatt taaaaaatat agaaaagatt tcttcaataa
     4201 gaagaattta tggaggagct gtactagcta gagaaacact agagaatcag gatacaaaag
     4261 acagaaaaga aattaatatt ccaacaaaga aaataatagc agaaaaagca tttaatttaa
     4321 ttgaagatag agaaactata tttttagata tctctacaat taacatcttg cttgcgaagt
     4381 tgttagctga aagtaataaa aaagtaacac ttattacaaa tatgctggat atactaaatg
     4441 tagttacttc aaaaccaaat aatttaaata taatttccac tggaggttta ttaaatctca
     4501 gtttagacgg ttttgtcggt actccaacta tagagtttat atcgaaatat aagtttgata
     4561 agacttttat gggaagttgt ggagtagatg tattcaactc ttcacttaca acttttgaaa
     4621 ttgaagatgg tcttacgaag aaggctataa taaattcaag taaaaaagta tttatagtta
     4681 tggaagataa aaagtttaaa tttgatggaa atttcaagtt tgctcattta gaagatatta
     4741 gttctataat tacagaaaaa acgcctactc ctgatatagt agatatttta tcagaattta
     4801 atgtaaatgt tttataagtt taattatata ttttatagga tttcttataa atataaattt
     4861 ttatttgata actattctta aaaacatatt tctataatat ttattttatc cttagtatct
     4921 attttttaaa atctagttct ataacatcta ctttatcctt atgtctattt ataaaactaa
     4981 tttgaaatag actttctaaa tctaatacag ttatttttag aaagtctatt tccttaaata
     5041 aactatttaa tattactggc tactttttat atgaatacaa taatttgtta ttcataaata
     5101 aaagcttatt tcatttcatt cttcatttgc ttctctaatt ctttagaaaa tttcttttgt
     5161 tcatatcttt ccatcatctc atcttttttc atttctaagt ttaccatagc accttgtgca
     5221 tcatctttca aatcttcagc tgtatttttc ataacataag ctgtcttttt aacaccttct
     5281 tttaaatctt ctttcatatt tttcatatct ctttttaatc tatccatcaa aactacctcc
     5341 tctgtaaata taatacttcc tatatttatt tttcccaaag tacatatatt tatttgtaat
     5401 atcaattata atttttaagt cttaaatata gtttaaacta tctaaatcta tacatttcaa
     5461 taaattaaat attttttatt tcaaaataaa aataacacta agcatagatt atatgctcgg
     5521 tgttattttt taaattcata gtaacttaat tgttgggtta ctataatgat gacttatatg
     5581 gaggatgtaa ggaaatctca tcattatagt tggtgtattt tatggtttta agcttcttta
     5641 tatttatata atacagtttc attatgaatt ttttgtgatt ttaaaatgaa ctattattga
     5701 aagttatata ttctttataa taagtaatta atttttaaat tctactgtga atactacaga
     5761 gttttctttg ttttttatgc tataatcaaa cccatgactt ttaaaaattt ggctgactat
     5821 ataaagtcca agtccacttc ctccagtttt tcttgaacga gatttttcta ttctataaaa
     5881 tggattaaat atttcttcta aataacgttt ctcgatagtt acaccagtat tttcaatttc
     5941 taaaaccact ctttgattag aagtcttttt acttattcgt ttatttttat catagagtct
     6001 aattataagc tctgattctt caggagaata ttttatggca ttatttatta tattattgat
     6061 tgccttagtt attctctctt ggtctgcttt aatttccaaa ttttcttcta tttttaaaat
     6121 agttttcata tgtttttctt ctattaaaaa tacttgtctc tttacaagtc tatttaataa
     6181 ttcacttata tttattgata ccaatttcaa atctttttca agtatttctg attttgaaac
     6241 ctctatcatt tcatttacta aatcttttaa ttcttgtgta cactcatacg attttttcag
     6301 ataagtatcc ctatccttat acttacctac actataaatc ataccttcaa tttgaccact
     6361 tattatggtt attggagttt ttagttcatg tgatattgta gcaacaaaat ccttccttct
     6421 atattcctgt tctctctcac tctctattat gtttataaga ggctttgtta ttacaattga
     6481 atatatatat gctccaataa tcgctatcaa tattgctatt gatatgatgt atggcattag
     6541 ttttcttata acttcgtttg cttcgtcaat tggttgtaat ggcataacga gttctaaagt
     6601 atatggacca tcttttgcat ctttagtata tataggtata gaagttctat actcatcctc
     6661 aagactatta atcatgtact tactatatct taaaataact acttcattct taccatatac
     6721 aattttacct tggttatctt ttaataaaat agccaaattt tggtctttag ccatataata
     6781 aagtctttct tctaaagtat atgtatcgaa atgaattgaa ctatctacta aagatttcaa
     6841 actttcttga agagactcaa ttttatactc atgataatat gatggcaata aaaaatataa
     6901 aattagatat attattaaag ctaatgctat taataatgat gtcgttattg aaaataactt
     6961 atactttata cttaactttt cccacttatc aaatatcctt ctcaagtgta tatcctattc
     7021 cttttacagt tttaatatat ggtaatgata ttttttttct tatatttttt atatgtgcat
     7081 caacaatcct agtatctcca taatagtcat aaccccatat actatccaaa agaccttccc
     7141 tagttataac ttgtggatac ttttctatca aagcttttaa tatattaaac tcttttagtg
     7201 taagttctat aggttctcca tctatctctg caatatatgt gtttaaatct aattttaatt
     7261 tttcaaaaac tataaatttg tcatttatag tcttgttact tcgccttaaa attgcttcta
     7321 ctctttttat aagaagatta aatgaaaatg gttttgttat ataatcatca cattctaagt
     7381 caaacccttt aagttggtct ccttcatcat ttaaagcagt taaaaatata attggaacgc
     7441 ttgatgactt tcttatcatt ttacaaactc cataaccatc taagtttggc atcattatat
     7501 ctaatattac taaatcataa cttccttgct taaacttttg tataccttcc aacccatcat
     7561 ttgctgtatc aacttgataa ccttctgcac ttaaaaattc tgatattaac tcttgtatat
     7621 ttgaatcatc ttcaattaca agtattgacg aattcattct atcaatcctt tctattttat
     7681 ttaaaatttc gtatattact tatattttat cttattgttg tgaattttac atgaaaaaag
     7741 agctatctta atttgtaaat taatcctttt aatttaaaga tagctctttt ggatacattt
     7801 tatttaattt attaatctaa tctctcttat atgccttgaa gtttttaagt ctaagtgcat
     7861 ttgatacgac tgaaactgaa cttaagctca ttgctgctgc tgcaatcatt gggtttaata
     7921 aaggtcctcc aaatacatat aatattcctg ctgctacagg tataccaatt gtattatatc
     7981 caaatgccca aaataggttt tgttttatat tttttatagt ttcatgacta agtttaattg
     8041 ctgttggaac atcaattaaa tcactcttca taagtactat atccgcagat tcaatggcta
     8101 catccgttcc acttcctatt gctatcccta tatctgcttt tgcaagagct ggggcatcat
     8161 ttattccatc ccctaccatt gcaacaaact ttccttgatt ttgtagtttt tcaacttctt
     8221 ttgacttatc ttctggtaaa acctctgcca aaaccatatc tatacctact tgatttgcta
     8281 tagcatttgc agttttcgca ttatctccag ttaccattgc aacttttatt cccatatcat
     8341 gaagtatttc tattgctttt ttactacttt ctttgactac atctgcaact gctattatac
     8401 ctgataaatt tccatctaca gctatataca taggtgtttt accttggctt gccaatatat
     8461 ttgatttttc ttctaaatcc ccaagcttta tattattgtc attcataagc tttctatttc
     8521 caagtaatat actttcatca ttaatagtaa cttgtatacc agcacctggt atagctttaa
     8581 aattatcaac tttttcaaat tttatattct tctcttctcc atacttaact attgcttctc
     8641 caaggggatg ttctgaacct ttttctgcac ttgaagcaat cttgataaga tattcttctt
     8701 ttacattatt atttaatact atatctgtta cttttggctt tccttctgtt atagtacctg
     8761 tcttatcaaa tatcactgta tttactttat gtgcagattc tagtgcctct ccacctttta
     8821 tcaagattcc attttctgcg ccctttccag tcccaaccat tatagcagtt ggtgttgcta
     8881 atcctaatgc acaaggacaa gcaattacaa gtactgatat aaatatagta agtacaaata
     8941 ctatatcttt tcctcctatt aaaaaccaca ataatgatgc aactacagct attgcaatta
     9001 ctattggtac aaaatatcca gatacagtat cggcaagttt agcaataggt gcttttgtac
     9061 cttgtgcatc ttcaactaac tttattattt gggcaagagc agtatctcca ccaatttttt
     9121 cagccttaaa cttaataaca ccatttttat taatactagc tcctgtcacc ttacttccaa
     9181 cattcttttc tactggtata ctttcacctg taagcattga ttcatcaact gatgtatatc
     9241 cttctattac aactccatcc acgggtattt tagttcctgg ttttactaat agtatatctc
     9301 ctatctctac ttcttctata ggagtttcta cttctttacc atcaactaac actattgcag
     9361 ttttaggttg tagccccata agctttttaa ttgcttctga tgtttttcct tttgattttg
     9421 attctaaata tttaccaagt aagataagtg ctattattat tcctgcactt tcataataca
     9481 actgatgatg gtgcatacct tgaatttgtc cattggctat ttgtagtgtc gtatatagac
     9541 tatataaaaa tgcggctaat gttcctattg caactaaaga atccatatta ggacttaaag
     9601 aaaaaagtga tttaaaccca tttatataaa atttataacc agctatcatt actggtatta
     9661 ctaaaattaa ctggattaat gcataattaa aagtatttgt cataggattt ataatttctg
     9721 gcaaaggcca tggccctata ggctttatta tcataggtcc cattgctata taaaacagag
     9781 gtactgcaaa tactattgca actataaatt taacaaataa agacttcatt tctctttctt
     9841 ttctcaattt atcttcatcc acatcaacct tatttcttac ctcttctatt ggtttatatc
     9901 cagctttttc aatagctgct tttatttgag ataattttac ttttgatggg tcatagtcta
     9961 tattagcttt atctgttgca atattcacac taatactttc tactccatcc aattttttta
    10021 ccactctctc tacagctttt gcacaagctg cacatgtcat tccatcaatt ttcatatcaa
    10081 tttttttatt actttcttcc tttataattc catatcctgc tttttctaca acctgcttta
    10141 tatcatcaaa attaacctta gaattatcat attctatttt aagtttttca gtagctatat
    10201 ttacactttg gtcatatact ccatccatct tcttagttac tctctctact gcctttgcac
    10261 aagctgcaca tgtcatacct gtaattttat aactttctac cactttattt gaactcataa
    10321 taaaatcttc ctttctttca atatattttc agctaatttg taacgtttta ttttgatatg
    10381 taatattgat aaattactta tttagaaatc tatattttta ttataccccc tataggtata
    10441 ttaaatcaat atttttttaa taaataaatg tattagttat atttatttgt atttaataga
    10501 aaagtatact cataattaaa tgtatatata aaaatagagc atctaaattg tttaatgctt
    10561 atacaattta gatgctctat ttattataat ttatatttta tttaaaattt attctttaca
    10621 tgcttcaaaa aactctgctt ctgtttcctt tatttcaagc tcattgtcta ttattccaac
    10681 agcttctttt ttaaatgctc tacactgacc tatacaacca gtctttacat tttcttctcc
    10741 aaccaaagtt tttagcttat ttacatccac atttgaacag tttggacata ctcttatcat
    10801 atttaagttc ctcctaatta atgtctaatt aatactttta tacccaaata taaactttat
    10861 aaaagttttt ttaatataaa ttattaccat atataccatt tatatcctat tgcgagtatt
    10921 acatattaat tttatatatt attaatacta catgtacggt ggtatctgtt gttttctcac
    10981 tatttccaat tccttaattt ctaaagactt aatcacattt actttatagt tttctttaga
    11041 ctttatatac aaaacatctt ctatcttttt accttcaata aatttatgag accacttaag
    11101 aagttcttca aaattacaaa cttcttcttt tacaaaagta tcactttcac ttgcaaaata
    11161 tttaattatt attttggtta cttccaacat atatcatcct ttactctttt attaatcttt
    11221 ttatctatta aggttattat ttgtctaaaa aattttttta aacagaataa ttttcagatg
    11281 caaaactaac agttttatcc aatttaaact atattaatac aatttaatat attcctcctt
    11341 gtacctaata atatattgtg ctataattaa taagttattt taatcgaagg gagcaacaaa
    11401 aatgtcacaa aaacataaaa ttataaatat cgcagttata gcccacgttg acgctggaaa
    11461 atcaacattg gttgatgctt tcctttctca aagcggtgtt tttagaaaga acgaagtagt
    11521 taaagactgc gttatggaca gtaacgacct tgaaaaagaa agaggcataa ctatatattc
    11581 aaaaaactgt gcaataaact atgaagatta caaaataaac atagttgata ctccaggaca
    11641 cagtgacttt tcttctgaag ttgaacgtgt tatgaaaact gttgacacag ttattctatt
    11701 agttgatgct agtgaaggcc caatgcctca aactagattc gttttacaaa aatctttaga
    11761 gttcggttta aaaccaatat tatttataaa caagattgat aaaaaagacc agagagcgga
    11821 agaagtagtt aatgaagttt tcgatttatt tgtagactta aatgcaacag atgagcaatg
    11881 cgaatttcct ataatatatg gtattgctaa acaaggtatt gctaaacttg aaatggatga
    11941 tgatagtgaa gacctttctc ctctatttaa aactattgta aatcacgttg aagcttatcc
    12001 taattacgat aatgaacctc tacagttcca aatatcagct cttgcatatg atgattatgt
    12061 aggtagactt ggtataggta gaatttacaa aggtactctt aaaaacaata cacaagttgc
    12121 tatatgtaga gaagattctg ttgtatctaa aggaaaagta tcaaaacttt ctgtgtatga
    12181 aggtttaaaa caagttgaag ttgatgaagc tactagtgga gaaatagttg ttatagctgg
    12241 tattcctgat atatctatag gtgaaactat atgcgattta gatagtccac tacctatgga
    12301 aatgataaaa atagaagagc ctactctttc tatgaacttc ttagtaaacg actctccatt
    12361 cgttggaaaa agtggaaaat tcgttacaac tagacatttg aaagatagac ttgaaaaaga
    12421 acttgaagta aatgttggtc ttaaagttga acctcttgat actactgatg gatacaaagt
    12481 ttctggacgt ggagagcttc acttatctat actacttgaa aatatgagac gtgaaggtta
    12541 tgaagttggt gtttctaaac ctgaagtttt aatgcataaa gaagatggaa aactaatgga
    12601 accaatagaa agagttgttg taaactgtcc tgaagtttac tctggtacta ttataaatga
    12661 attaaacatg agaaaaggta tgatggagtc tatgtcaata gaaggagact atgtaaaaat
    12721 agagttctta gcacctactc gtggtctttt aggatatcga agtgaattta taaacgctac
    12781 tcgtggagaa ggtactttag ttcgttcatt tgaaaaattt gaagaattta aaggagaaat
    12841 accttcaaga ggaaatggtg ttttaatagc acaaggacct ggtgttacta tggggtattc
    12901 tcttaatgcc ttaagtgata gagctgtaat gtttgtagac cctggtgtag aagtttacga
    12961 aggtatgata attggtatga attccagaaa agatgatatg gtagtcaatc cttgtaaaaa
    13021 caagaaaatg agtaacgtac gtgcttctgg ttcagatgat gctataaaat tatctcctcc
    13081 tagaatattt actcttgaag aagctctaga gtttatagaa gatgatgaat tagttgaaat
    13141 tacacctgat tctataagac ttagaaaaag attcttaaat gaacatgata gattaagata
    13201 taacaaatct agacaaggta aataaaacgt acatttacct ctaattaaca aaatagccat
    13261 atagtactga aaaattattt cagtttatat ggctattttt atttgaaatt tatattattc
    13321 aacatttata taattagctg cttgaacggc tgcaatagct ccatctgatg ctgctgttat
    13381 tatttgacgt aaaaacttag ttctactatc tcctgctaca tatacacctt ctactgatgt
    13441 tgtacaagac tcatctgaaa ttatatatcc accttcatcc aaatcaagaa cattttcaaa
    13501 cattttatta ttaggtttaa gacctatagc aataaaaata ccactaacat ctatagttct
    13561 tttttcttca gtctttaagt tttttacttc tattttcgat acagtctttt ctccttctat
    13621 tttttctaca ccatgactgt aaagtatctc aatattctct cttgctttca cagatttctc
    13681 caacacttct tcacctctaa aactatctct tctgtgaatt aaatacactt ttgtacaatt
    13741 attagctaaa aataaagcat cttctagtgc agtatttcct ccacctacta tagcaacttc
    13801 tttatcttta aaaaaggctc catcacatgt tgcacagtaa gatactcctc tacctgtaaa
    13861 ttcttgttcc cctgcacaac ctaatttacg tctttcaact ccatttgcaa gaataacagc
    13921 ctttgcttta tgttcacctg aagaagtttt tacaaccttt acttttccct ctaaatttat
    13981 ctcttcaacc tcatcaaact gaatatcaac accttgagca actgcttgat tgtatatatt
    14041 attagaaaat tctaccccag aaatcttttg aactgctgga taattttcta cctcagaggt
    14101 acttgcaact tgacctccat aaatattttt ttcaaatact gtaacgctta accctgctct
    14161 catagcataa attgctgaag ttaaacctgc tggtccagca ccaattacaa tgatatctac
    14221 cataacgttt acctctcttt atattattat ttcttatata ttattctcat cattcttata
    14281 ctttactatt attatccata tatactataa acaaaacatt attttttatt aattaacttt
    14341 attttacata tatataaaaa aactgcaaat aaaaattaac ttttatttac agttctcact
    14401 tatttatata attcaaaacc ttattggtta tcatttacag tgtcttctaa tatattgctt
    14461 tctgatatat atgatagaat tgaaagtcca tacataacca aaactaatgc tgctgttata
    14521 agtactattc ccatatttaa tacctccttt tgtttacagt atactattat tatgtgaaat
    14581 atttatgaat ttaatttgaa tatatatgta atttcacact aacaatttct tcaaattaaa
    14641 cattattaac tatatacttt tgttgaacca attatgatta atagtttaaa tattagcact
    14701 atttacttat atttatatga tataccatat aattacattt ttcaaattaa agttttgtaa
    14761 actttttttg taatatagtg tagtataaaa ttgtaatatt acagatattt aatagttatc
    14821 ttttgattac tttcattaaa aacagcttca tcactatgaa aatctaggtt tttaaacttt
    14881 taaaaaagtt aaaaaaatat ttttctaata ctcaatttga ttacaatttt tttacaattt
    14941 aaaaaatatt ttttccaaat ttttatatta atacttgact ttgtctgttt tataaactag
    15001 aataattaat aatattaaga atattgaaag gcattgatta ggaagagtaa atctgaatcg
    15061 attaccagag aaggaaacta ctagctgaaa tgtttcccta attagaagga ttgaaaacta
    15121 cctaggagct tctatccgaa gttatcttaa tgattttagt aggaatagac gtttttatta
    15181 cttgcgttaa agtatcaagt ggatttttta aaatcaattt gggtggaacc gcgggaaaca
    15241 gattctcgtc ccttttttag ggatgagggt ctttttttat tacctaaatt cagtttttaa
    15301 aatattctgt atctaattta attagctaat taaaaattta aaatatatgg aggattataa
    15361 aaaatgtatt attcaagtac gagaggcacc gaagaaaaag taactgcatc acaagcaata
    15421 ataaaaggaa tatcaaatga tggtggtctt tatgttccaa gtgaatttcc caatgtaaaa
    15481 aatgaactta taaatttagt aaatttaacg tattctcaga tagcattttt tgtacttagt
    15541 aaatttttat gtgattttac tgaagatgaa attaaaaatt gtatagaaaa tgcatatgat
    15601 gaaaagtttg attgtagtag tatagctcca ttaaataaag taaatgatac ttatttctta
    15661 gaactatatc acggtccaac tttagcattt aaagatatgg cacttactat aatgcctcat
    15721 cttcttaaaa catctataaa gaaagataat ttagagaaag atgttgtgat tcttactgct
    15781 acatctggag atacaggtaa agctgcactt gagggattta aagatataga taaaataaag
    15841 ataattgtat tcttcccaga agatggtgta agcccagtac aaaaacttca aatgaaaact
    15901 caaactggaa aaaatacata tgtagttggt ataaaaggaa attttgatga tgcacaatca
    15961 ggtgtaaaaa agattttttc tgataaagaa tttaatcaaa aactattgga taataattat
    16021 atattatctt ctgcaaattc aattaatata ggaagacttc ttccacaagt tgcatactat
    16081 ttttattcat atatgaaatt agttagcaat agtgagataa atttaaatga taaaataaat
    16141 tttgttgtcc caactggtaa ttttggtaat attctagctg gatattatgc caaacaaatg
    16201 ggtcttccaa taaacaaatt gatatgtgca tcaaatgata ataatgttct ttatgatttc
    16261 tttaaaactg gtgtatatga taaaaataga acattgaaat taactacttc tccttctatg
    16321 gatatattaa tttcaagtaa tttagaacga ttactgtttg aaatatcaaa tagaaatact
    16381 gatattgtaa ataagctgtt atcagacctt agtgataaag gagtctacaa aataagtgat
    16441 gatatggaaa aaaatttagc ctcattctat ggagaatatt caaatgaaga agaagttaaa
    16501 agcacgataa acaatgtgtt taaaaattat aattatttga tagatactca tactgctgtt
    16561 gcatacaatt gttatgaaaa atataaaaaa gaaacttctg ataacacaaa aactgttatt
    16621 gtaagtactg caagtccatt caagttttct gaagatgttc taaagtctat agattgtgat
    16681 tttaaagacc ttgatgactt tgctataatt gatagattat caagtatttc taaaatagat
    16741 attccaaaac ctattaaaaa tcttaaaaat gcagaaatac tacataaaga tatttatgaa
    16801 aaagatgaat taaaactagc tataaaaaaa ttcttaaagg tataggtgat tattatgtta
    16861 gagattatag ttcctgcaac aagtgctaat ataggtccag gatttgattg tcttggaatt
    16921 gcgttaaata tatacaataa attttatgtt gaagaaattg aaagtggtct tgaaatagaa
    16981 ggttgtgaag atgcttacaa aaacgaaaac aacttagttt atacatctat gaagtacttt
    17041 tttgatagag ttaaaccagg aaaaatacct gctggtatca aaataaaaat ccaaagtgaa
    17101 gtacctatat gtagaggtct tggcagtagt gcctcttgta tagtagctgg agttatagct
    17161 gcaaatgctc tatcaggtgc taatttagat aaaaatcaat tactaaatat agcttcagaa
    17221 atagaaggtc acccagataa tgttgctcct gctattttag gaaatatgat tgtatctgtt
    17281 actgataatg agaacataca ttatgatatt ataaaaattc ctgaagaact taaattttgt
    17341 gcaatgatac ctaattttaa gttatcaaca gaaaaagcta gaggtgtttt accaaaggaa
    17401 ataccatatt ctgatggggt attcaatgtt agtagagttg ctttactaat atctgcctta
    17461 ctaaacaaaa actttgacct acttaaagta gcttgtcaag acaaattgca tcaagattat
    17521 agaggaactc taattgaaaa ctacaatgat attgttgaaa aatctgaaca attaaatagt
    17581 attggagtat ttttaagtgg agctggacct actataatgt ctttaataaa agaaaatgat
    17641 gatagttttg tggataatat gaaaaattac ctacaaaaac taaaatctga ttgggaaata
    17701 aaagagttat gttgcgattc taatggagct gttttaaata taatataatt atcgtcttct
    17761 atacaaaata taactactct tttattataa tttgtagtat aataattagg actaggtaat
    17821 aatattaagt attataatct agttctttaa acatgtttac attgaggagg gattatcata
    17881 aaagagttaa taattagaga tttagttgca aaagttccta taattcaagg tggaatgggc
    17941 gttggtatat ctaggtcatc actagctggt gcagttgcta agcttggtgg tgttggtgta
    18001 atttctggag ttcaaattgg atatgatgag gaagattttg aaactaatac tataaatgca
    18061 aatttaagag ctataaaaaa acatatttct aaggccaaag aaatctcaaa tggtggtatt
    18121 attggtatta attttatggt agctatgaaa gaatatgaaa catacgtaaa ggaagctgtt
    18181 aaagctggtg tagaccttat aatatctgga gctggattac ctaataagct accatcatta
    18241 gtaaagggaa gtaatgtaaa aatagcaccc atagtttcaa ctgcaaaagc tgctaatgta
    18301 attttaaaaa tgtgggatag aaaagagaaa actactgctg acttaatagt tgttgaaggt
    18361 ccaaaagctg gtggtcacct tggatactct aacgaggaac ttgataacat agattctata
    18421 gactatgata aggaatttgt tgaaatttta aaggttgcaa atacttatgg agaaaaattt
    18481 ggtagaaaca taccagtagt tgctgctggt ggtataactt ctagtagtga tgttaaaaaa
    18541 tatatagata tgggtgcaag tggtgtacaa gttggtacaa gatttgttgc tacttacgaa
    18601 tgtgatgccc atgagaactt taaaatggca tacataaatg ctagtgaaga agacgttcat
    18661 atagttaaaa gtcctgtagg tcttcctgga cgcgccataa gaaacaaatt tatagaagaa
    18721 gttaaaataa atcgtccaga aataaagaag tgctataatt gtttgattcc ttgtaatcca
    18781 aaagaaactc cttactgtat ttctcaagct ctaatcaatg cagttaaagg agatgttgaa
    18841 aattcacttt tattttgtgg aaatgatgcc tataaaattg ataaattaag tactgttgaa
    18901 gatgttatca atgaattgat ttctgaatta taatttaaag aaaactaaat taagatttta
    18961 tcaagctaag gagtttaaat acgttattta ttaatcttta taaacatatt tatgtcctta
    19021 gcttttttgt gtcaatttcc ttttatggaa attttaattt aattagagat agtattaacc
    19081 cttataacta atcttctttt acaagtacat tggttatttc agctatatat aaagtatgat
    19141 aatctttttg tggataccat cttccatcta taccttcagc aataaaacat tgaggttcaa
    19201 gtttctgact atacattttt ttgcatataa tagccatttt agattcttta aaataaggtg
    19261 tatcatttaa gtgttctata ttaaatccaa tctgtgatat cttatcctct tctctaccag
    19321 atacttttcc acaatatgaa agctctttac gaaaatcttc atcaaaaaat gtaagagaaa
    19381 atttatctgt attatctata aattccttag tataacgctg tggtcttatt actacaaaag
    19441 caacatcttt tccccacata actccaagcc ctccccagct agcagtcatt gtattcactt
    19501 taccttcatt ttctgctgtt ataagtgtcc aatctttacc tatcaatcca aatggattat
    19561 ttttaatctc ttctgccaaa atttctttaa aatcactcat atctctaata acctctcatt
    19621 ctcttatatt tatattcctt ttattttcat gataaattat aaatgaagtc tagttttgaa
    19681 aataaaatac ttttttaaat atattattgc aaataagtaa atatatatat acactcttat
    19741 tttttaatat atttaataat ttcactcaga atatatatat tctttactca aattaaatat
    19801 aacttatata ctttatgtgt aaattatggt aaaaatatta tttaatcaaa tcaaaacttg
    19861 atttatatac ctggaaaagg tattatatta aagagtgctt aaaatacgca tttcataaat
    19921 agctatatat aaaataataa ataaggagag tgatgggcaa tggatactag tccgttgcgg
    19981 agagaatttt ttacattttc atcacttaat aatatctaaa atcaaaacta atacatatat
    20041 tcagttatat aaattagtta attaatagat actattaaat gatgagattt atataaaact
    20101 gaataaagga tgtgttgcca tgataagata ttacaaaact atagattcaa aattagagaa
    20161 acttagtttt tttgaagatg gctgttggat aaatcttgtt gaacctaatc atagtgaaat
    20221 caacgaaatt tctaatttat taaatataga tgtagaaagc atagaatctg cactagatga
    20281 agaagaacgc tcaagaatag atgttgaaga caatcatact cttatactta tagatatacc
    20341 agtagacgaa agtgactcta attcttctca ttatactaca atacccttag gtattatact
    20401 aactgaagaa gctattgtaa cagtttgtga tgcacaaact aagattttaa atgactttat
    20461 agttggtcat attaaagatt tttttacatt taaaaagact cgctttttgc ttcaaattct
    20521 tcacaaaaat gcagcttatt acttgcatta cttaagaaaa ataaataaaa tgacaataat
    20581 aatagagcga gaaatttaca aatcaatgaa aaacaaagaa ttggttcaat tattggaatt
    20641 agaaaaatct ttggtatact tctctacctc actaaaatct aatgaacttg ttttaaacaa
    20701 aatggttaga actgctggta taaagaagta tccagatgat gaagacctat tagaagatgt
    20761 tatagttgaa aatagacagg ctcttgatat ggctaaaata tatggagata tattgagtag
    20821 aattatggat gctttcagtg caattataag taataatcag aataatgtta tgcaaatttt
    20881 aacagtagtt acactaattt tctcaatacc tacaataata tcaggattct ttggtatgaa
    20941 tgtcatcaac atgccatttt ctaataaccc aaacggattt tggataatac ttcttattac
    21001 ctctataata tgtatagtga ttacattttt catgtcaaga aataagctat tataaaatat
    21061 taataaaaaa gccattagaa ttaattgatt tacatttatc ctaatggctt ttatatattt
    21121 aaatctatat aatcttataa tactttttaa ctatcatgtt cttcatctat aatcatttca
    21181 gtttcaagcc cttctagcat tgaatctaaa ctttctttta tatttagtat ataaattggt
    21241 acatactctt cttcatctat tacctcttct tgcaacttaa atggaggaat taatacttca
    21301 tcaaagtcta tatttaaatt aggaaagcct tctactatct cttcacaatt atcgtactct
    21361 tcatttgcta aagaaacgta catatctagg ctctttttat aataaagacc tgcaagcata
    21421 tactcacact tcttacttcc atatttaata ccttctttat aatatttctc agcttctgcg
    21481 tcatcattta attttaaata aatttgacct aaattatata ttgattcaac acaaccttgt
    21541 gctctagcct tttcatacca aaatttagaa tttacataat ctttatagaa catatcataa
    21601 attaatccta ccatatgttg agcatacaca ttattttcat tggcaggtgt atcaaacatc
    21661 attttagact cttccaattt accttctcta aaataaattc tacctagatg tatacgagca
    21721 ttcatatggt ttttgctact tgccatttca aaatactttc tagcattttt tgtatttcct
    21781 aagctctcat atatacaccc caatctataa ctagacctcg tatctccatt ttcagatgct
    21841 ttcttatacc aacttattgc ttcttcaata ttatttaaat cttcatagat atttcctaat
    21901 ttgatttgac aagatacatt atttggaatc ctcgaataat acgaaatcgc tttttctata
    21961 tcttgattct gataatataa atcccctaga ttttcaaggg aacttttgca tccaacagct
    22021 atagcatcct cataatattt aatagcattt tcataatctt tttcttcaaa atatatacct
    22081 gccagattat tttttgcctc tgttatatca tcttcagcag ccattttata ataagttttt
    22141 gccttctcta tctcattttc tctattatat aaattagcaa gtctatactt agaaagtgta
    22201 tgattttttt ctattgcttt ctcataataa taaattgcat ctcccagctc ttcttttcta
    22261 tcatatacat atgcaagcct atactcagac ttcacatcat ctctatcagc actcttttta
    22321 taatacttct ctgcatcttc taaattatca tttatttcca taatcatacc caagttaaag
    22381 caacctttca tatgacctga cttgtataac tgtttatata aacttactgt tgatttatta
    22441 tctttctttt ttccatttaa tattgctaaa ttatattttg catcatcatc taaaagcaca
    22501 gaaccttttt tatagtattc atatgcttca tcatctttct ccaaaaaagt atataatacc
    22561 cctaaattaa aacaagcttt acctaaattc ttgtctgctg ctgtttttaa ccatttttca
    22621 caccttacaa aatctttcat tttaaaatgg catacaccta aattattttg tgcttgtaaa
    22681 taacctaaat ttgctatctt ttcataccaa tatatagcat attcatagcc atctaactta
    22741 tagtacatat tacctaaatc aaaagcagca tcttcacttc cacttttata tgccattgaa
    22801 taccactttt ctgcttcttt aaattgtttt ttactttcat atatatttcc taaagtatat
    22861 tgagatttta cgtaattatc caatgcagca ctcttataca actctattgc gctttccatc
    22921 ttacccatct tttcaaggag ggcaccctta gtatgtacga ctttcgggtc attagatata
    22981 ttttttattt tttttataga aaattttgta tttttcatta ttcgctacct acccatttta
    23041 taaaatatat tctctcaaac attattatac attataatct acaattaatg ctataatatt
    23101 gaatttttac cttttgtcac tatattgtaa cattaaattt taaattttat aatcattaga
    23161 ttttattatg taattggtat ataatgtata tatagggggg acattttatg aatttcagca
    23221 atatttttat ccaagttgca gttttattta taattatttt agttggatat tttgtcagaa
    23281 aattcaactt attagatgac cactgcacat ctaagctttc aactttgaca atgacagttt
    23341 ttttaccatc aatgataatt agctccatgc aaattaactt tgatagtaaa atgatacaaa
    23401 aaatactatt gttattattt acatctttga ttatgtatat agtttcaatt ataactgcat
    23461 ttttattgaa atacatttta aaatgtaatg ataaaaaaga tttgggaata tatcagtata
    23521 tagttgtttt ttcaaatgtt gcttttatgg gttatcctgt aattgaagca gttttaggtc
    23581 atgaagcaat attctatact gcaatattca atttgccttt taacttattt tctttcactt
    23641 taggaattta tcttttatct aaaggcagta caagtagagg tttttcaata aaatcactta
    23701 taagccctgc tacaatagct attgttattg gacttttttt atttgtaaca ggacttaggt
    23761 taccccaatt tataaacgag ccacttgaga tgttgggaag tataactaca ccaatatcca
    23821 tgattatcat tggaagctta cttgctaatt cttcagctct cgattgtttt gtcaacaaaa
    23881 aattatatat agtcactttt ataagattat tggtacttcc tgtgattgtg tattttattc
    23941 taaaaggatg gataaatgat aagatgattt tagctatacc agtagtaatt tcttcaatgc
    24001 ctgctgctgc aaatactgct ataatggcta atcaatatga ctccaatata acactagctt
    24061 cacaatgtgt gttttttaca acactatttt cagttatatc tatacctttt ataagtattt
    24121 tactcttatc ttgatttatt tttttatgta ttatataata acatattcaa taaattacaa
    24181 atataaacat tttattgtag tatattgatg gaattttttc ctagatattt gtcaataata
    24241 tctatatgta ttatagaata ggaggcttaa atatggatat ggatttactc tttaaaatag
    24301 tatttgctat agttgctata ggtgtttctg taaaaatcat taaaactgtt gctagtttag
    24361 cttttaaaat agcgttgata ttgctaataa ttttatttgt atatagaatg tttttgtaaa
    24421 catttaaaaa taagtttttt aacacaatag agaagtaaaa tagattatct ttaatgtaaa
    24481 ttttttatta aagacactct attttacttc tctattagct tctttaaatt aaatttttat
    24541 tatatcttcc cataatataa acatcttcaa attttccatc tctgattaca gcatattttt
    24601 tagttccctc tatttcaaaa cctagctttt tatataaatt taatcccttt tcattatcca
    24661 caattacttc taatcctact ctagttaaca taatccaatt atctgctata tctaaaagtt
    24721 gttccataag cttcttacct actcctcttc cctgataatt ctctgcaaca cttattccta
    24781 tttctgcgct atgtctcaat cgtggagaag aatttacatg taacccagca aaacctatta
    24841 catctttttc tccattatta ttagtttcag ctacaaacat ataatcattt tctcccaaag
    24901 aagctaacat agcttcagtt ttatcgactc tgtcactcat taatgccaaa gtatttctca
    24961 taacactgta tgttcttcta atttcattaa aagcttgtgc atcttctctt cttataggtc
    25021 ttattgttat atctataggc ttactcatat tggattcccc ctcaaacata atctttattt
    25081 ttaattaaaa ttttacatct ttattttata ctgttcaaat ctatgtatgc ttctacctga
    25141 ggtacatata tcatattatc ttttatatgt gtacttccaa attcttttaa ttctgtacct
    25201 tctttatcct tagttatttt atatctaatg gattccatac cttcaactac ttcagcatga
    25261 aaaaacatac cttcatattg tttaaatcta aaattaaaat tgtctttagt aagttttatt
    25321 atcatatttt tatctactcc ttatataatt gatatttttc ttattattag ttgtatatat
    25381 actgcttatt catattaata tattataact tatcatttat ttagtataaa gttataaata
    25441 gatatattta tacttatttt acaatctttc ttcaattgat atataatatg tttatataaa
    25501 ctaatgtatg tgaggtgaaa tatgagcaaa aaaacaaaat atttttcttt aattctcttt
    25561 cctattgctt tgcttttaaa ttttatagcc agtaaagttc caaatattgt tgaaaaatat
    25621 tactcccaat tcatagataa aataattgta caaatattga gtaaagtttc tggaattttc
    25681 ccattttctc tctatgagat tacaatgtac ataatagtta tatctatctt cttattttta
    25741 tgttgtactt tatctacaat ttttaataag aaaaaaaaat taaacatata tttaaaaaat
    25801 tccattttaa atatattatc cattgtatca atagtctact ttctttttgt agtgctttgg
    25861 ggaataaact ataataggat tccactagaa accacactta taaataacta taatttaaaa
    25921 aacgatacct ctatccaatc aaaacaatat agtgttaaag agcttactaa attatataaa
    25981 ttccttgtaa ttaaagcaaa tgaaactaga aaactcacat tacaagataa aaatggtatt
    26041 gtaaaatcta atacagatta taatggtgtc ataaatagag ctcaactagg atacgataat
    26101 atcttggata tattacctag tgttagtggt agttattcta agcctaagta tattatttca
    26161 tcaaatctaa tgtgctatac aggaataact ggtatatact ttccttttac aggtgaggca
    26221 aatgtaaata tagcaatacc tgacttatat attccttgta cagttgaaca tgaaatggca
    26281 catcaaaggg gatttgctag tgaagatgag gctaatttta tagcgtatct tacttctata
    26341 aaacacccca atattgattt taactattct ggatatattt tagctttaaa ttatactgct
    26401 tctgctttaa gtaaggttga ttataatgca tatgttgata tttctgctgg catttcagat
    26461 tctgtccgta gagatttaaa aaatgaaagt gaattttggc aaaaatatga aggtaaaatt
    26521 aatgaaattt ctaatgagtt taacaattct tacttaaaag ctaatggcgt tactgaaggt
    26581 actcagagtt atggtaaaat ggttgattta ttgctaactt attatgaatt atatccatat
    26641 aactaaacac tacaattcaa aattttattc atatacagct gatattaaat cagctgtttt
    26701 ctatttaaat aaattattta acttcaagca atcttatata atttgatagt acttatacta
    26761 gctgtataac atttcaattc taactatttt agttaaaaca tttctattat cttttttaat
    26821 aaatgtttta actaaaattt ttaaaacata aaacttccac attatttcac tatctatata
    26881 aaaatctaaa aattcacata taaaattaca taactaaaaa atcataaatt tatagaaaac
    26941 atatattcaa aataaaaaag catgtatcaa aacttgacac atgcttataa tcttatgtat
    27001 atatatcatt ttgtcacaat aaaaatttcc ttgtaacact gatattttta aacaaaatag
    27061 tccttattta attaaattaa cattaattaa attcgtactc attttgctat cattaaacat
    27121 tacttatagt aattttctaa tacactattt gaaacttcct tcccttgaaa acttttcaac
    27181 caattctcat atgctgaatt tttccataca ctaccatcat taaatgttac ttgttttaca
    27241 caagatataa tgtactttac accatgctct ccagttgatt gtttccattt atcaaacaat
    27301 agaaaggcat cattttgatt cttacctggt gctattgcat tttgctttgc atattctttc
    27361 tccatttgtt tccattcttt caaccaattt tctacccatg ccttgccttg ttgtttttca
    27421 aacatactta ttatatcctg tggtggtgat tgttgcattt ttctataagt atgtgaatat
    27481 gattttggag acacaggaga tatgcctgta acaataccat agtctacacc agctgggcta
    27541 aatccaacac ttcctacttc gccatctgct gccacatttt gagcatccca atatagctca
    27601 agtggttttc catttttatc atatgctaag catgtaattt cataatccat aattgccttt
    27661 tcactgctat ttgttaagct tataacattg ctaggccaat gatatggagt atcatcatac
    27721 tgtattttgc tattatttat aaataatgga atattctcat tataaacaag acctttacta
    27781 ctttgaatat ctgatacttt ctttgtgaca gtacttaccg tatttgctaa gtatacattt
    27841 gttttttctg aattggtcgt actaagagaa aatgttgttg tcgttccagt aatcagcaaa
    27901 gcaacaacta aaataggtaa gctagatatt tttttatatc tcacagttct tcacctcttt
    27961 ttctattaac ttataataaa acaatttacc aaaacattaa aatctatgtt aacataattt
    28021 accaactgtt ctagtaacta tatcctatca tagttactat caagtttcaa tactattgat
    28081 ggaaattttc actatattaa atctttttta attttataaa tttacaatat gatttaactc
    28141 atacatatat agtcaaatta gaatataagt ttcttacatt taatgaagtt tataaaataa
    28201 aaaatgacta gataattaaa tactgtaaat aaaaacttat tacaaaagta tttaaaaatc
    28261 tagtcaatta atatatatat gaattgtata ctataatttt tcaatctctt ctagcaactc
    28321 atcaactaat ttgttaccat caatcattct aactatttca ccctttttaa ataaaagacc
    28381 ttcaccttta cccccagcaa tacctatatc tgcctctctg gcttcaccag gtccatttac
    28441 agcacagccc ataattgcaa cagtgatatt tttttccata ctaccaatct tttcttcaac
    28501 ctcatttaca acactaatta agtctatatt acatctacca catgtagggc atgatataac
    28561 tttaatctta tcatttaaaa gtcccaaact tcttaaaatc tgtttaccaa caataacctc
    28621 ttcaacaggg tcgcctgtta aagatattct aacagtatct ccaattcctt taagaagaag
    28681 tgctcctacc cctatagaag actttattgt tcctttgtga acacttccag attctgtaat
    28741 tccaatatga agaggataat caactttttt tgatattaat tcatatgcat caacagtttt
    28801 ataaatatcg gatgatttta gagatataac tatattatga aaatctaagt cttcaagaat
    28861 cttaatatgt cccattgcac tttcaactaa tgcttcagca gttgcagagc catacttttt
    28921 taaaagttct ttctctaaag aacctccatt aactccaatt ctaattttta aatttctttc
    28981 cttgcatttc tcaactacca tcttaactct ctctatactt ccaatattac caggatttat
    29041 tcttattcca tccacacctt gttctatagc ttcaagggct agcttataat cgaaatgtat
    29101 atctgcaata attggtatat ttacactaga ctttatcttt gctatatttt tagcagcttt
    29161 aatatcagga acagcaactc taactatatc acaaccagct tcctctaatc tctttatttg
    29221 agctattgta gcatctgcat ctcttgtatc agtatttgtc atagattgta tacttatagg
    29281 attttctcct cctattttta cagttcctac acttacttct ctcgtctttc ttctctcgta
    29341 actcatattc cacctctata tattatttta tattgaatct ctttaaatat taaaatatta
    29401 taacctacat gtatattata aattaaaaag ctatctagtt aaataagaat aaatttcata
    29461 tataaaaatt aatttattct tatttaaaac tacatagcct attttcttaa aatctctaaa
    29521 aaactaaatc attgaaataa tcttagtata tctttatatg tgataaaaag cataaataac
    29581 attaaagctc caaaaccaac aacatttatc atgccttctt tatttgggtc gagtttttta
    29641 ccacctctaa cagcttctag taacaacata agtattctcc atccatcaag tgctggtatt
    29701 ggtaatagat ttactatacc taaatttaag cttatgacag ctgctaaata cactacattt
    29761 atgatgcctg tacgagcagc atctgatacc ataccaataa cacctactgg tcctgctaca
    29821 gcattgccaa tccctcctgg tacacgtcct gtaatcattt gacctagaaa tgttagcatc
    29881 tgttttgtca tatctacagt agttttacat gcatttacta ttgaccctaa aaagtctttt
    29941 tctctttgcg gttgaatccc tatttcatac tttccattgt tatttttagg tgttacattt
    30001 acaactttat cacttccatc tctagttata ctaagtttta attctccacc agaagaagta
    30061 tttattatat ttgcaacttc atcccaagtc ttaacagaat taccattaat tttatttatc
    30121 ttatctccta cttgaagccc tacagcctgt gcaggagtat ctggcattat ctttcctaat
    30181 ttagtcgttg gagaacctat atacaaaaat actggaacta aaagtattgc tgctaatatt
    30241 atattgaata ttggtcctgc tacaatagta ctaaatcttt gtaatataga cttgtttcca
    30301 aaagaatttg gacttatttg ttcttcatct tcaccttcca tgctgacata tccaccaatt
    30361 ggaagtgctc ttatagaata ctctgtatct ttttttacgc tatatatctt aggccccata
    30421 cctatagaaa actcatttac tttgatacca cttctttttg caaatataaa atgtcctaac
    30481 tcatgtatta atacaattat actaaatagt attaatgcgg ctattatagt cataaattca
    30541 ccttcctatt tttttatcag atttgcaaca taagctctac tccatctatc tgtttctaag
    30601 atttcttcta atgttggttc acttatgcta ctatgaactt ctaaagtctt ctctatgtaa
    30661 tatggtatgt catagaaacc aattttatcc tctaaaaatt cacttactaa aacttcattt
    30721 gctgaattta aaacagaaga ataagttcct cccattttta aacactcata tgccaatttt
    30781 aaacatggaa aagtttctaa atctggttct tcaaaagtta aagtactaaa ttttgaaaaa
    30841 ttcattcttt caaagctact ttccattcta tctggatatg taagagcata ctgtattggt
    30901 agtctcatat ctggacatcc taattgagca attattgagc tatctgtata ctgcaccatt
    30961 gaatgaatta tgctttgtgg gtgaactact acatctatat tttcttgttc tactccaaat
    31021 aaccatctag cttctatcac ttcaagtcct ttattcataa gcgttgaaga atcaatactt
    31081 atttttcttc ccatactcca atttggatgc ttcaaagctt catttttagt tatatttgca
    31141 agttctccct ttttctttcc tctaaatgga ccaccagatg ctgtaagtat tatcttttct
    31201 atattttttt tattttctcc atttagacat tgaaatatag cactatgttc actatcaaca
    31261 ggaagaatat ttacattgta tttttctgct tctttcatta caagttcacc agcagttacc
    31321 aacgtttctt tattcgctaa tgctatgtct attcccttct ttatagcaca aagagttggg
    31381 actaatccta tcatacctac tacagcagtt aaaaggacat ccacttcatc aagtgatgat
    31441 attattttta atccttccat tcctgctaaa acttctattt ctatattttt aggcaacatt
    31501 tcttttaatt tcaatgcttt attttcctca aaaactgtta catatttagg tttaaactct
    31561 actatctgtt ctagcaataa ttcaatatta ctgttagctg atattgcgac tatctcaaac
    31621 ttatctctat tatctctaac tacatccaaa gtttgtttac ctatagagcc tgtagaacct
    31681 aaaattgata tctttttcat ataataatcc tttctaataa taaatatacc ctgtcaaaac
    31741 attataacac tactaaaaca attattttta ctattcatag aaatttcata tattattcca
    31801 cagattaaaa ttaatctatt attttttgta ttttgtggaa tattataaaa tattctagta
    31861 ttattaaatg ccctttttta tttccacaac atcttctatt ttacagtcta gtgctaaaca
    31921 tatcttctcc attgtatcca tagaaacaga tttatcattt cctagtctgc ctaaaacaga
    31981 aatacttata cttgatatat ttacaaattc cattttcttt atttttttgt caattaacaa
    32041 tttccataat ggagcgtatg aaatcatgtt atcacctcgc aaaatatatt ctatcacatt
    32101 ttatctattt tggaaaattt tcatctattt agataaataa ttatttatct aaatagattt
    32161 caattatagt ttattaaata taaatatgtt aaaataaaac aaaagcataa gttcaaaaat
    32221 taaactttat atatatttat ctcattattt tactaaaaca t
//
LOCUS       DAEQAF010000043        30649 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.044, whole genome shotgun sequence.
ACCESSION   DAEQAF010000043 DAEQAF010000000
VERSION     DAEQAF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 30649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30649
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.044"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            115..2016
                     /locus_tag="KRN00_002033"
     CDS             115..2016
                     /locus_tag="KRN00_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1827899.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVAGNASDFKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            2019..3062
                     /gene="ypdE"
                     /locus_tag="KRN00_002034"
     CDS             2019..3062
                     /gene="ypdE"
                     /locus_tag="KRN00_002034"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1827900.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNKKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            3077..3382
                     /locus_tag="KRN00_002035"
     CDS             3077..3382
                     /locus_tag="KRN00_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1827901.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            3479..3814
                     /locus_tag="KRN00_002036"
     CDS             3479..3814
                     /locus_tag="KRN00_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1827902.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            3846..5168
                     /locus_tag="KRN00_002037"
     CDS             3846..5168
                     /locus_tag="KRN00_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1827903.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAILLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            5178..6248
                     /locus_tag="KRN00_002038"
     CDS             5178..6248
                     /locus_tag="KRN00_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1827904.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNINKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGKYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            6253..7440
                     /locus_tag="KRN00_002039"
     CDS             6253..7440
                     /locus_tag="KRN00_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1827905.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVINNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKDFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(7636..8508)
                     /locus_tag="KRN00_002040"
     CDS             complement(7636..8508)
                     /locus_tag="KRN00_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBH1827906.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNVLWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(8902..9093)
                     /locus_tag="KRN00_002041"
     CDS             complement(8902..9093)
                     /locus_tag="KRN00_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827907.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            9313..10359
                     /gene="cobT"
                     /locus_tag="KRN00_002042"
     CDS             9313..10359
                     /gene="cobT"
                     /locus_tag="KRN00_002042"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBH1827908.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            10391..10951
                     /gene="cobU"
                     /locus_tag="KRN00_002043"
     CDS             10391..10951
                     /gene="cobU"
                     /locus_tag="KRN00_002043"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBH1827909.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            10961..11734
                     /gene="cobS"
                     /locus_tag="KRN00_002044"
     CDS             10961..11734
                     /gene="cobS"
                     /locus_tag="KRN00_002044"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBH1827910.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            11754..12368
                     /locus_tag="KRN00_002045"
     CDS             11754..12368
                     /locus_tag="KRN00_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH1827911.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENNSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      12435..12614
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            12744..14243
                     /locus_tag="KRN00_002046"
     CDS             12744..14243
                     /locus_tag="KRN00_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBH1827912.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            14282..15658
                     /locus_tag="KRN00_002047"
     CDS             14282..15658
                     /locus_tag="KRN00_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBH1827913.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDASVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNK"
     gene            15659..16630
                     /locus_tag="KRN00_002048"
     CDS             15659..16630
                     /locus_tag="KRN00_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH1827914.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKFGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            16662..17732
                     /locus_tag="KRN00_002049"
     CDS             16662..17732
                     /locus_tag="KRN00_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1827915.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            17734..18612
                     /locus_tag="KRN00_002050"
     CDS             17734..18612
                     /locus_tag="KRN00_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBH1827916.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKFMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIE"
     gene            18609..19241
                     /locus_tag="KRN00_002051"
     CDS             18609..19241
                     /locus_tag="KRN00_002051"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBH1827917.1"
                     /translation="MKYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            19250..20476
                     /locus_tag="KRN00_002052"
     CDS             19250..20476
                     /locus_tag="KRN00_002052"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBH1827918.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCKERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            20473..21081
                     /locus_tag="KRN00_002053"
     CDS             20473..21081
                     /locus_tag="KRN00_002053"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBH1827919.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNVVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRMDNFDMNVVVILDEE"
     gene            21071..21646
                     /locus_tag="KRN00_002054"
     CDS             21071..21646
                     /locus_tag="KRN00_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBH1827920.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            21639..22391
                     /locus_tag="KRN00_002055"
     CDS             21639..22391
                     /locus_tag="KRN00_002055"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBH1827921.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            22375..23496
                     /gene="cbiG"
                     /locus_tag="KRN00_002056"
     CDS             22375..23496
                     /gene="cbiG"
                     /locus_tag="KRN00_002056"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBH1827922.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVYTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            23493..24218
                     /gene="cobJ"
                     /locus_tag="KRN00_002057"
     CDS             23493..24218
                     /gene="cobJ"
                     /locus_tag="KRN00_002057"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBH1827923.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKGGDTPVGVVKDVGREKEEKFVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            24215..24967
                     /gene="cobK"
                     /locus_tag="KRN00_002058"
     CDS             24215..24967
                     /gene="cobK"
                     /locus_tag="KRN00_002058"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBH1827924.1"
                     /translation="MILILGGTSDSLSICDKINELKNQSYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            24986..26464
                     /locus_tag="KRN00_002059"
     CDS             24986..26464
                     /locus_tag="KRN00_002059"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBH1827925.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            26494..27399
                     /gene="hemC"
                     /locus_tag="KRN00_002060"
     CDS             26494..27399
                     /gene="hemC"
                     /locus_tag="KRN00_002060"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBH1827926.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            27389..28888
                     /gene="cobA"
                     /locus_tag="KRN00_002061"
     CDS             27389..28888
                     /gene="cobA"
                     /locus_tag="KRN00_002061"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBH1827927.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            28905..29870
                     /gene="hemB"
                     /locus_tag="KRN00_002062"
     CDS             28905..29870
                     /gene="hemB"
                     /locus_tag="KRN00_002062"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBH1827928.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            30023..30601
                     /locus_tag="KRN00_002063"
     CDS             30023..30601
                     /locus_tag="KRN00_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBH1827929.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCRAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEKRYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        12409 a         3058 c         5664 g         9518 t
ORIGIN      
        1 ttaaaatata ctaggatata aagttcttaa ataaaaagaa aaggttgttt ttataaaaaa
       61 tattttttat accactttaa aaaacacaat aataacactg agggaggtgg ggatatgaga
      121 gaacgcatta ttcttgaaac attaaaaaat agtagtggtt atctaaacat agattatttt
      181 gcagataagt tgggggtatc tactcgaact atcagaaatg aaataaaaaa gatagaaact
      241 ataaaagaat gtaatggttt taaattagaa tataagtcta aattaggata tattctaaat
      301 attaaagacc aagataaatt cgagcattat ctaagaaact taccctcaga tttagttgaa
      361 aatccagaac aacggttgga gtctataata gtagagcttt tagtaaatga aggttataaa
      421 actatagaac agttaagtaa aaaatttcta gtaagttcat cccaaataaa aaatgattta
      481 aaaaagatag atgaaaagat aaaggataca gaattaaaac tagagcgaaa ggctcattat
      541 ggaattaaaa tagaaggttc tataaaagaa attcaaagta tattggtgga tagttatttt
      601 agagggaata gaaatataac agagtacagg aataagttta tagataattt aaaattagct
      661 aatattagaa gtacaataaa aaatgtactt aatgaacatg atttagaagc aaatttaaca
      721 gaacttgagg aaatattagc acaaattatt atattgtata taagagttag tatgagagta
      781 gcgggaaatg ctagcgattt taaattatat acagaagatt taattataga taaattatta
      841 gataaaattt ttagagataa aaaatataac cttaattatg atgaaaagta ttatttaaag
      901 gagcttataa aactaaagac taaagataag aaagccacta taaagaatat tgataagaat
      961 aaacttcaag atattatgtt cgaatttttt agagagatag ataaaaaata taactctaat
     1021 tttttagaag ataaagagtt ctttaactta ttttacttac atattgcatg tttaatagaa
     1081 cgtataaaga agaaccacaa gataataaat cctttttcag ttaaaataag tcaacagtat
     1141 ccaactgttt ttaatttatc tattcaattt tcaaaaatca tagaaaatga gtatcatata
     1201 aaaataagtc aagatgaaat agggtttata gctactcaca ttgctgttcc ttttgaaaag
     1261 agagaagaag ctaattttaa taaaaaatat aaaatagcaa taatatgctc ttctggtgga
     1321 ggtagtgcat ttttgataaa tttaagactt aaagaaattt ttccaaatgc tgagataaga
     1381 aatttttcat tactagaaga aaaagctgta atagaatttg caccagattt gattttttca
     1441 ataacaaatc ttttatttga aataaatgct ccagttatac ttataaatga aattttagac
     1501 gaattggatt atttagatat taaagaaagt gttagatttg cagaccatat aggaaatata
     1561 tcaagcccaa aacaatatat attaggtcta tttgataaga atcactttag gtgtataaaa
     1621 gataaagcta agtataagga tatccttgat agtatgtcaa aatgtatagt tgacgaggga
     1681 gcttgttctc caacctatcc caaagatgta tgggaaagag aaagctattt gagtactatt
     1741 tatacaaatg gggtggctat acctcatcca atcgagatga caggaaacaa aaatataata
     1801 tcagtagctt tgatacaaac tgatattatt tatgaaaata gggtgcctaa aattattttc
     1861 atgatttcat taataaaggg aaatttagaa cttcataagc aaatatctaa atatttaagt
     1921 aagattatgg caaataagga tatggtagac atgctaaata agtcacaatc ttatgaagag
     1981 tttatgtata agttaaaaat ctatctggga ggttagacat gaatatagag ttttttaaga
     2041 ggttgtcgga agcagatggt atagcatcta atgaagaaga ggttagacat gttttattgg
     2101 aagaactaaa agcttatagt gataaaatta tctgtgatgg gctagggagt atcatctttt
     2161 ctaaaataaa agatgagagt gcaccaaacg taatgatttg tgctcatatg gatgaagttg
     2221 gatttatggt gagaagtata gataaacttg gtatgattca cttaataaca ataggaggag
     2281 taaaacctct tgcacagttt gtacaaaaag ttagaattac aacaaaagaa ggaaagaaaa
     2341 tccccgctgt cataaatgct acatataata atggtaaggc tgaaaatata tatgcagata
     2401 ttggagcata tacagaagaa gatgtatata acctagggat taatgttggg gatatggtaa
     2461 catatacaac aagttttgag gaatttactt taccagaccg attagtggga aaggcttttg
     2521 atgataggat aggatgtttt gtgatgggag aagttttaaa agaacttagg aaagaaaatc
     2581 taaattgtaa tattcacttt gcagctacaa gtagtgaaga ggttggaata aggggagcaa
     2641 agacatcaac acagttaata aatccagata tagtatttgt aatagatgta gcatgtgcta
     2701 aaaatgagtt tgtgagagac tatacaaata agaaacaaat tgataaaggt gtaatgctaa
     2761 tgcatagaga taggactcta gtccctagta gaaaaatgat agattatgta atggaaattg
     2821 ctgataaaaa taatatacca cttcaacatg atatgtttga atcaggtggg actgatggag
     2881 gagaagcaca tctcgtaaat gaagggaaac cttgtgtagt aacttgtgta ccagttagat
     2941 atggtcattg tgcattttca atagtaagta ataaagattt ggagaacatt ataagattgt
     3001 atacacagtt aattttaaat tttgatgaag aacaatataa acatataaga aattttatct
     3061 aaaggagaat aagaaaatgt caacagaagt acaaataatg gaacttatat caactgcagg
     3121 agagagtaaa tcgaaagctt ttgaggcttt aaaaaaagtg aagtcaaaag attttaaagg
     3181 agcaaaattg ttaatagagg aggctcgtaa aatagatatt gaagctcaca ggatacaaac
     3241 agaattaata actcaagatt taaatgaaga tgttgaaagt ccagcaatga gtcttttaat
     3301 ggtacatgct caagaccact atatgacttc tcagctagca aaagacttga tagaggcttt
     3361 gatatattgt ctcgataagt aattgtaatg tagaaataga ttatttatgt aaaaattctt
     3421 ttaaaagttt agatgctttt aagagataat aaaaatacaa actttaggag gaattattat
     3481 gaaaatatta ttatgttgtg caggtggatt ttctactaat atgttaatgc aaaatatgaa
     3541 aaaggtggta aaagagagtg ctaaactcaa tgaaaaagat tttgagttta cagctatacc
     3601 agcagattca atagaaagtg aagttgatga ttgggatata gtacttatag gtcctcaaat
     3661 agctcacaaa atagacttct taaaaggaat attagagcca aaaaataagc cttttgcagt
     3721 aatagataaa gatgtatatg gaaaaatgga tggagctaca gttatgaagt tggcattaat
     3781 aacttataag aaacatcaat tagctcaagg ataataaaaa taatgaggga aaagggagat
     3841 tagatatgtt ttcaaaattt gaagcattta tgaatagagt atttatgcct ttagctcata
     3901 aggttgacaa tcaacgtcac cttggttcta taaaggctgg tatggttgct atgacaccat
     3961 tcacaatatt aggaagtata tttgcaatac ttccagcact tccaaatatg cttggagaaa
     4021 ataatccaat aagcaaattc atacttaaca attcagcaat attggattta ccagtaagtc
     4081 tttccatagg tttaatagga ttatatgctt gtatgtgtat tgcttttaat ctggggaact
     4141 actataaatt atatatacca ggttgtgttg cactatcaac tttttctttt ttattcctag
     4201 tagcctcatt tacaccagat ggagctttag aaataggaaa tttaggagct aaagggctat
     4261 ttacaggtat gatagcaggg cttggttctg tggagttata taatttttgt aataagaaga
     4321 atatcacaat aaaaatgcca gaaaatgtac ctgattttgt atctaggtct tttgaattaa
     4381 tacctactac tataatagtt tgtggaactt ttatagttgc tcgttttatt tcattaaaag
     4441 tatttggaga attacctcca cagatactta ctcaattttt atctccatta gtaggaagta
     4501 tggataaccc atggtcagtt cttgcactta actttgctat atgtactata ttcttttttg
     4561 gaatacattc atcagtattt agccctataa ctagacctat aatgattaca tttatagctg
     4621 aaaacatagc agctatgcag gctggagaaa caatacctca tttctttaca gcaggagctt
     4681 caagtgcatt ctttggattt acaggatgtg gaattagtat aggttgtgta attgcatgta
     4741 tgttatcaaa aaatgcttcc tataagaaga ttggacgtgt atcattattc cctgcattat
     4801 ttgggataaa tgaaccaata ttatttggag caccgataat attaaatcca ataatgttta
     4861 taccacatgt atttggtgga gctataatag gtacactacc aatgtttttt atgcactggg
     4921 gatggttagc aaagccagta tttgaccctc catatgtagg ggtattctta gaaggatttt
     4981 taactaatgg agattggcat tctatattag caaatgcatt gcaattagta ttagcaattt
     5041 tattatattg gccattcttt aaaataatgg aacgtcaaca aaataataaa aaacaaaaag
     5101 aagaaactaa gaatatattc tctaaagaag aagaagactt attggatgat ttaggattgg
     5161 atttctaata ttttgttatg aataatacaa tggagagatt agtatcctta atctataaaa
     5221 gaggtgttga cgctcttttg attaaagcaa aaaatactaa aagatatata ggagctttat
     5281 caggtagtgg tgtatatgtg cttgttacta aggataaaaa ttatcaaatt ctagatggca
     5341 gatatattga tgaagcagat aaaaaaacga ctggtttcat aaaaaggatt gtatctcaag
     5401 gttcttatat accaactata attgagttat taaaagaatt aaatataaac aagttagcaa
     5461 tagaaaacca agctatgagt atacaagagt atctttcact aaaaaatgaa ggttttgaaa
     5521 tcaatttaat aacaaatgaa ttatggaagc taagggctat aaaatctaaa gaagaaattg
     5581 aacttattaa aaaggcttgt gaaattacag atgaagtatt tgatgaggtt atttctgaaa
     5641 ttaaaaaaga tatgactgag ttagaagtat cagctctaat tcagtatcat gcattaaaaa
     5701 aaggtgcaag tggaatgtct tttgaaacaa tagtggtatc aggagaaaga ggtgcaatgc
     5761 cacatggaag acctacaaac aaaaaattga aagtgaatga agctataaca atagattttg
     5821 gtgttgttta tcaagggtat caatcagaca tgactcgtac aatatctata ggtaaacctc
     5881 ctaaaattat taaagagata tatgatgtag tattggaagc acaattatct gcaatagagt
     5941 caataaagga aggaactagg gcaagtgatg ttgacaaagt ggctagaaaa attatagata
     6001 aacatggatt tggcaaatat tttaatcatg gactgggtca tggtataggt cttggagatg
     6061 gtgaagtccc cactttaaat ccaaatagtg aagatatatt agtggaagga atggtaatgt
     6121 cttgtgagcc aggtatttat attccaaatg tagggggagt tagaatagaa gatgacattg
     6181 ttataataga tggaaaaggt gttccactca ataagacatc caaagagttt ataatattag
     6241 gagagtaaaa ttatgaaata taattttaat aaagtattaa atcgtaaaga aggaaattgt
     6301 agaaaatgga gcaaccatgt gattaaagaa aaattcggct taaatgaaga tgcaattcct
     6361 atggatttag ctgatatcga ttttgagtgt gctcctgcta taaaagaatc tatcttaaaa
     6421 agagcatcag taggagatta tagttatact tttataggag atgacttcta tgatgcgatt
     6481 ataaattgga ataaaagaag atttgatgta tatatagaaa aggattggat aaaattaact
     6541 tttggtactg tttcaaccct tcattatata gtccaagcat atactaaaga aggagagggt
     6601 gtattgataa atacacctgc ttatgaccct tttgcagagg ctgtaataaa taataataga
     6661 aagttgtgtt gtagctcatt aaaattagat aacaatagat attatttaga tttagaggat
     6721 atggaaaatc aaatgaaata cgagaatata agattgctta tattctgtag tccacaaaat
     6781 ccatcaggtc gtatatggac aaaagaagaa ctatatcaag tgtcagagtt atgtttaaag
     6841 tataatgtaa ttttggtaag tgatgaaatt catagagata taatatttaa agattatagg
     6901 tttgtatctt tatggaatgc tcatccggaa atttataaaa atagtataat ctgtgtatct
     6961 cctaataaag gcttcaactt aggtggatta aaaacatcat atgtattaat aagagatgta
     7021 aaaattaggg agactttatt agaaaggcta aaaagtaatt caataacttc tccaaatgta
     7081 tttgcaatac cagcaatcgt tgcagcgtac aatgaaagcg aagaatggct agatgctatg
     7141 actagttatg tagaggagaa ttttgaaata gtttatgatt tctttgaaac taatatacca
     7201 aaagccaaag tgatgaagtc agactcttct tttttagcct ggatagatgt aagagaagtg
     7261 tttagaaatg aagaagaatc taaagacttt tttagacatg caaacttaac tatggtagtt
     7321 ggaagttatt ttgtgaaaga tggagatgga tttattcgta ttaatgtggg gtgtcctaga
     7381 gaaacattaa atgaggctct aaatagaatc aaaaaaacgt atataagtat gtattgttaa
     7441 atcataaaaa agtatctatg gtttatataa aaacacatta tttagttatc aaatattact
     7501 ggaattttgt attccagtaa tattttttga ttaaggaata ttattgagga atattaaata
     7561 atattatttc atacccttat attaacttat ataaaaatat tttattattt tgggaacggg
     7621 ttagctaacc tttatctagt gtatatttat attgtaagaa gcagtaaaaa cttttccttt
     7681 actaagttta ttaataaact tcttatcttt ataaattttg ttagaattta tactatcagc
     7741 aagaccatac caaggttcta tacataaaaa aggagcagta gaattagttt cactataata
     7801 aggagtccaa ataccaacta gagggaaatc ttccatagat atagttacat atttactacc
     7861 atcattatta catatagaca cttcatctat gttggtgtat atcaaagcat cattcttgaa
     7921 tacttctgga tttaactgta agttttttaa ttttccaata ggtattatat catctgtaaa
     7981 agaaccattt aaattgattt tttctacatc atttttactt ttaaactcaa ggtagtgttt
     8041 agaaaaatca ttttgttcgt aaaaaggaag gttgaatgca ggatgtccac ctatagaaaa
     8101 gaatatatct ttagaatcag tattttttac aatccattct acctcaatac tattatcatt
     8161 taatgtatag tttatgatta gctcaaaaga atatggatac ttctttaaag tagattcatt
     8221 atctgttaat ttataagtta caaatgtatc tcctttatct acaatctcaa agtccatatc
     8281 tctagcaaac ccatgttgag tcatgctata taaattttct tctattattg tttcattatc
     8341 aaaaagttta cctactatag ggaacaatat aggtgattgt ctaccccaat attttttatt
     8401 accatcccaa agaacgtttt tgtcgtattt tttagaaaat attttagtta gttcagcacc
     8461 aaaactgctt gattcgataa ttaaattttc attttgtaat atattcattt aaaatctcct
     8521 ttattatatt ttatgagtat attatactat aaagtataaa gattattaaa ttttatttga
     8581 tattatattt gaaaggtaga ttttagtata ttttgaaaat tttgttttga aaatttggga
     8641 ttatttaaga aattttgtat tataaataga aggaaataga taaattgtat agaataaaat
     8701 atattaagat aagttaataa tgttaaatgg gaagtgagtt tatggaaaaa ccaaatacaa
     8761 aagttgttaa ctttcaagag tataaagaca gaaaaaacca aagagaagta aatagagacg
     8821 aacttttaaa gcttataaaa aaaattgtga cttcaaaata gggagttgtt aaactcccta
     8881 ttttaatggg tttcataata attaagacat tctgagtcca tctatataat ctttgaattg
     8941 tgagaaatct gattcactac ttaattctat ggtttctgaa ccttccgtat aaaaattctt
     9001 aagatagata gtataattat tatcaacaca atcatgataa atacatctat atccatcttc
     9061 atacaaactt tttaatttag aaaaatcatc cacaatatca tctccttaaa gttcttttaa
     9121 atatattttt acaaaaagca tctaattgta tgcaaattga caatgtaaaa taaaggaaat
     9181 gaacataaaa tgtagaataa tttttatatg tatgtaaaaa taaaaagaaa aagttgaaat
     9241 ttttagaaaa taagagtatt ttttatctaa aaagagagtt taaaaaataa aaaaatgttg
     9301 ggaggataaa aaatgagttt attagaaagt atatcaaaaa acatatattc cctagataac
     9361 tcttctattg aaaaaacaaa gcagagattg gataggctta tacatccaac tggaagctta
     9421 ggaaagatag aagatatttg catgcaatta gcaggaatat ttggcaatga aaattttgac
     9481 acaagtaaaa aggttataat tgcttttgcg ggagaccatg gtgtatatga agaaggcgta
     9541 gcacctgacc ctcaaaatat aacaaaatta cagtttccaa atttttcgaa aggtctatgt
     9601 ggagttggag taataagtaa atttgtaggg gcagatgttg tagctgtaga tgtaggaata
     9661 aactgtgatg aaaaactgga tggggtatta gactacaaga taagaaaagg gacatcaaat
     9721 atggcaaaag gtccagctat gagtaaacaa gaagccatta gatgtttaga gataggtatt
     9781 gaaatagcag agcagtgtat agaaaaagat tataaggtta ttggtattgg ggagatgggt
     9841 atagcaaata ctactccaag tacagcaata atatctgtaa tttcagggtg tgacccgtta
     9901 gaagttactg gtataggtgc aggtcttaag aaagaaagac taaagcataa ggctgaagta
     9961 attagaaagg ctattgaaat taataatcca aatccaactg atggagtaga tattttatct
    10021 aaagtaggag gatttgaaat aggctcaatg gcaggtgtta tattaggttg tagtgctaat
    10081 aggattccag tagtaattga tgggtttatt tcttatgcag cagcattaat tgcatataag
    10141 ataaatccaa aaactagaga atatatgata gcatctcatt tatcagcaga atcaggaact
    10201 aaaagagcat tagacatatt aaaattagac cctctattaa atatggatat gagattaggt
    10261 gagggaagtg gagctgcttt agcatttgat ataatagaag cttcaaacta tacttataaa
    10321 aatatggcaa cttttgatga aattgacatg ggaagataaa tataaaaatt taatatgtag
    10381 gagtgttttg atgagtaaaa ttattctagt aacaggagga gctaggtcag ggaagagtaa
    10441 ctttgcagaa aaactatgtt ttgacagaaa taataataca gcttatatag caacctctat
    10501 tccatttgat gatgaaatga aagatagagt aaaaaaacat caagagaata gacctagaaa
    10561 ctggaatact tatgaaatat atgaagatat atattccata attaaggaga tatataaaga
    10621 acatgaaact gttatactag attgtgtaac attattagta aataatctaa tgtttgaaca
    10681 caatttaaat atagaagaat ctagtcaaga agaaataaac aaattagaac aatacataaa
    10741 agaacaagtt gtcaaactta ttgaagaaat agaaaaaaca aatctatact ttgtatttgt
    10801 aacgaatgag ttaggtatgg gaattgttcc tgggaataaa cttagtagaa tttatgctga
    10861 tattgtaggt cgtataaatc aatatatagc ttcgaaaagt aatgaagttt attttgtagt
    10921 tagtggcata gctatgaaga taaaggagta gtatgcaatt atgaaaagat ttattttaat
    10981 actacagttt ttgacaagga tacctataaa attaaatgta ggatttgatg atgaatttta
    11041 taagtcaata gtatattttc cacttgtagg ttttgtcata ggtatattat cctatttaat
    11101 aggatggatt tctatgcttt tatttgaacc atttatagct tctataataa taactctagc
    11161 tggtgtctta attactggag gacttcatat agatggatta ggagatacat ttgatgcaat
    11221 atatagttat agagataaag aaaaaatgct tgaaataatg aaagattcaa gattaggtac
    11281 aaattcactt ctagcaatta tgtttgtact tttattaaag gttggattcg tttacgatat
    11341 aataagtaat aattcattgt gggttataat ttttatgcca atgattgcaa ggttaggagt
    11401 aatgttattg acatataaaa ctgtgacacc aagagaaaaa ggaatgggaa atttatttat
    11461 aggaaaatta actacaagta tgttaataac tgctataata tacacattat tgatagttgc
    11521 tcttattact aaatttatat ttttattacc taatatagtg ttgattaaag tattaggttc
    11581 gattatagtg gtttttgtat ttataatatt attcaaaaaa catatttata aaaaaattga
    11641 cggagtaaca ggagatatat taggctgtgg aatagaactt tcagagcttg tatatttaat
    11701 ttacatatat ttgttaattt ttatgttttt ttaaagtaaa aagtggtgat aatatgataa
    11761 gattaatatt aataagacat gcactgacaa atgataataa aaaaggaaga ttatcaggcc
    11821 atataaatag ttgtattagt gaagagggca aactacaaat aaataaaatt accagatatc
    11881 tgagtaatga aaacatagat aaggtttata caacaccatc tacacgtact aaagatacag
    11941 tagaaaaaat atcaaaattg aaattattag aaatagaaga aaaagaagct ttaagagaaa
    12001 ttagttttgg agactttgaa ggaagaactt ttgaagaaat taaaatcaaa tatccaaatg
    12061 agtttgaaaa aatgataaaa gaaggtaaca actatagata tccaaatgga gaaagtttga
    12121 tagactctta taaaagagtg gcgaaagaaa ttgataatat aattttagaa aataatagta
    12181 atttagatac aaagacaata cttatatgtt ctcatgcagg aacaataaga aatataataa
    12241 cacatttgat ttctggtagt tataagtatc actggaactt taaaattgat aatgcatcta
    12301 ttacagtttt agaaattgat ggtggatttg ctgtaataga taaaatgaat tttacagact
    12361 tcatataatt taatcaaaac caaacattac aatctgtgtt tgtaatatat ctgtaaaatt
    12421 agcaatgaaa atagaatatt agattaaaat taggttctta attagatgtt aaaagggaaa
    12481 aaggttagat gcctttgcag cccccgctac tgtgaaacca acgaaactat aaataccact
    12541 gtcagtttga tgggaaggtt atagaagtag gatgaagtta agccaggata cctgcctaat
    12601 ttaatttaaa acaagaggtc ttcggggtga aagattttta attaatatat ataaaagtcc
    12661 tatctttaga agtattagga ctttttttta tttgtttttt agtaaatttt aacaaggagg
    12721 gatggaaagt ggggaaaaaa ataatgctac aaggaacagc ttcaaatgta ggtaaaagtg
    12781 tcttagtagc aggtttgtgt agaatattta agcaagatgg ttatactgtt gctcctttta
    12841 agtcacaaaa tatggcttta aattctttta taactaaaga aggattagaa atgggaagag
    12901 cacaagtatt tcaagcagag gctgcgaaaa tagagccaat agctgatatg aatccagttt
    12961 tattaaaacc ttctggaaat aataaaagtc aagttattgt aagaggtaaa gttgtaggag
    13021 aaatgccttc ttctaagtat catgattata aattggagtt agtagatgtg ttgaaggaaa
    13081 catttaatag cttaaattca aggtatgata ttgtagttat ggaaggggca ggaagtaatg
    13141 cagagataaa cttaaaagat agagatatct ctaatatggg tatggcagaa atagctgatg
    13201 cacctgtaat aatagtcgga gatattgata gaggaggcgt atttgcctca ttagcaggaa
    13261 caatgctttt attaaatgaa gatgagaaaa gaagagtaaa aggtgtaata atcaataaat
    13321 tcagaggaaa aaaagagctt ttacaagatg gtgtaaagat gctagaagac atcataaaag
    13381 tacctgttat aggagtagta ccttatacag atataaaaat agaagatgaa gacagtgtaa
    13441 ctacgagatt taagaaaaaa atgaataaaa gtgatataca catagaaata attagaaccc
    13501 cacatatgtc aaattttaca gattttaata tatttgagac acaagaagat gtaagtatta
    13561 gatatgtaga ctatggagaa tctttaggaa atccagatat attaataata cctggaacta
    13621 aaagtactat agacgattta acatatataa gaaaaagtgg tcttgaatcg caaatcaaaa
    13681 atttacatag tcaaggtaaa ttgatatttg ggatatgtgg tggataccaa atgttaggta
    13741 aaaaattaaa agacccttat catgttgaaa gtgaaattga agaagttgat ggaataggtc
    13801 ttttagatac agaaacaacg tttgagaaag aaaagactac aacacaagta gaagctacta
    13861 ttgttgaatg tatcagtgaa tacatgaata accttaaggg aaaaaaagta aaaggttatg
    13921 aaattcatat gggaattaca aagcgaggta atgatgtaag aagtttagat ttaataacta
    13981 aaaaacttga taaagaagtg aattatactg agggaagtgt aaataaagag gggaatgtaa
    14041 ttgggactta tcttcatgga atatttgatg aaataagctt tacaagagca attttaaaca
    14101 atataagaaa gaaaaaaggt ttaggagaat tagaaagcaa agtaaactct tttaatgaat
    14161 ttaaggataa agagtatgat aagttggctg attttttaag agaacattta gatatagaga
    14221 aaatatatga gattatgaaa taatgatgac ttttatttat aatttaggta ggaggtgtat
    14281 tatgaaaaaa attttaattg cgggtactaa tagtggagta ggtaaaacaa caatatcatt
    14341 aggaataatg caagctttgg ttaagagaaa tatgaaagta cagccatata aagtagggcc
    14401 agactatata gacccttcat atcacacttt tataactgga agacattcta gaaatttaga
    14461 ttcttatatg ttagatgatg aaaaaataaa gtatatagta aataagtcct caaaagatgc
    14521 agatatttca gtaatagaag gtgttatggg cttatatgat ggctttggaa tagatttaga
    14581 taattgtaca agttcacata cttcaaaggt attaaagtca cctgttatat tagttataaa
    14641 tggtaaatct atggcagcat ctagtgctgc tatggtactt ggatataagg aactagataa
    14701 agatgtaaat ataaaggggg ttatagtaaa taatgtaaag actaatagcc attatcaaat
    14761 aattaagagt tctatagaaa aatattgtaa tgttgaagta ttggggtatt ttcctccaaa
    14821 taacaaattc tctttggaat ctcgacatct aggattagtt cctagtgtag aaatgaaatc
    14881 actaagggaa aaattttata ccttagcaga tgaaattgaa cactatatag atattgacag
    14941 aataattgaa atatcagaaa gtgatgaatt tgagagtgat tttgattttc aaactttgat
    15001 agaaaataat aaaataaaag aacatgttaa taataaatca atagctatag catatgataa
    15061 agcattcaat ttttattata gagaaaatat agagctttta gaggaacttg gtttagaaat
    15121 aaactatttt agccctcttg aagatgcatc agtgccaaat gcagattata tttatattgg
    15181 aggaggtttt ccagaaatat ttggaaaaga attagaagca aatgagtcaa tgagaacttc
    15241 catattagaa gcacataaca ataatatacc tatttatgca gaatgtggag gactgatgta
    15301 cctaggtgag aaactattga atcaagaaga acaagaattt aatatggttg gaatatttag
    15361 tggaattagt aagatgacat cttctttaaa gagatttggg tactgtattg gtgtagccaa
    15421 ggaaaatact cttttatcta aaaaagggga atccattaaa gggcatgagt ttcatcattc
    15481 aatatttgaa agtgatgaaa aatgtgtata ttcaatgaga aaagaaagag atggaaatat
    15541 agtagaagag tgggatggtg gttatagtaa aggaaacact ttggctacat atcttcatac
    15601 tcatttttat aataacttaa attgtataga aaattttttg aaaaaaggaa ataagtaaat
    15661 gagtatttta tctatttata taggatatgt gacagactta attgtaggag acccatattc
    15721 ttttcctcat ccagtgagat ttattggtaa acttataaat tttactcaag gtataataag
    15781 aaaggtctct aaaaatgata ggcagttaaa atttggggga tttatattat ggtttataac
    15841 cgttggaata acatatttaa caacttatgc tatagtgaag ttatttagtt ttaatatatt
    15901 attgagtatt gtagtgaata gttttataat ttatacaaca ctagccacaa aatgtttaaa
    15961 agacgaagca ttaaaaattt ataatgtatt aaaaactgaa gatatagaaa aatctaggat
    16021 tcagctatct tatatagtag gtagggatac tactaattta agtgaacctg aaataataag
    16081 agcaactgta gaaactgttg cagaaaatac tgtagatggt ataattgcgc ctatgtttta
    16141 tgcatttatt ggaggagcac cacttgctat ggcctataaa gctatcaata cattggactc
    16201 aacagttgga tataaaaata aaaagtataa agatattggt tttgcatctg ctaagattga
    16261 tgatatagcc aattatatac cagctagaat atctgtcatt cttatgacaa ttggaagttt
    16321 ctttttaaat tataactata ggaactgttt taaaatctct attagagata gaaagaatca
    16381 taaaagtcca aattgtgctt tttcagaagg tgcagtatct ggtgctctag gaatacaact
    16441 aggaggtacc aacgtttatt ttggggaaaa agtatataag ccaacaatag gggataagct
    16501 tagggagata gataaagaag atataattaa aactaataaa attatgtatg catcttcatt
    16561 tgtatctatg ttggtattta cactaatata tgtgttatgt aggatgattt taattaactt
    16621 aattatataa attattgttt gttaacttaa gggggacata gatgaaggat ttagggcatg
    16681 gtgccaatgt agatgaaatg gcaagattat atgggaaaaa cccaaaagaa ataattgatt
    16741 ttagttcaaa cataaatcca aatgtattac caaatttaga gagatacatt ttaaaaggat
    16801 tagaagagtg taggaattat ccagatataa attatacaaa cttgagagaa aatatatcaa
    16861 aatatataga tataaatcca gactttataa tacctggcaa tggtgcaaca gaagtgattt
    16921 atttgcttat gaagagtatt aaaaaaaaat tggctataat aaatccgact ttttcagagt
    16981 atagaagaag tgctgagtta aataatttag atattataga tttagagtta gatttagaaa
    17041 ataactttaa acttaatata gatataataa aagaaaatat aaaaagattt gatagtttat
    17101 ttatatgtaa tcctaataat ccgagtggta atgtccaaga tttaaaggaa cttgttcatt
    17161 tactagataa acataataag gtactaataa ttgatgaaac tttcatggaa tttgttgaag
    17221 atgaaagtaa atatagtttg gttaaatata tagaatcaaa taaaaatata tttataatta
    17281 aagctgtgac taagtttttt ggtatgcctg gtttaaggct aggatatggt cttacaagca
    17341 acactgaaat tatgaacaaa atttatgaac acaaagagcc atggactatc aattcttttg
    17401 cagatatact atccaatttt atttttgaag ataaagagta tattaaaaat agtaaagaat
    17461 attacataga agaaagaaaa tatatgttac aagagttgag aaacataaga aatataaagg
    17521 tctatgatac agatgctaat tttatcttga taagaatata taaaaaaaca actaaagaat
    17581 tgaaaaaaga tttgtttaag caaggaaaca tattagttag agatgcatct aattttatag
    17641 gattagatga tagctttata agagtggcta taaaatctca tgaagataac aaaattctta
    17701 tagaaaatat gaaaaattta ttgggtgatt aaaatgaaat cttatggaat atgcccagca
    17761 tcttgtggag aatttgtaca aggtataatt gatgatgaag aatatttatg ttcatatgca
    17821 atagatatgt attctaaagt gtatattgaa gaaaaattag tagatataaa tttagggaga
    17881 tataagtcaa ggttagcaat tgaaaaggta tttgaaaaat ttaatctacc taaaaaatat
    17941 actaaaaata tttctttaaa tataaatagt aaaatacctg ttggaaaagg aatggcaagt
    18001 tcaactgctg atataggagc tactataaag gcaacattat cattgataga taaagattta
    18061 agtagcgagg agatttctaa attagcagca gaaatagaac caacagattc tatatttata
    18121 gataaaaata gtatatttaa tcctctaaat ggaactgtta taaaatacct aggaaatctg
    18181 accaatgcga aagttgtaat acttgaacca aacaaagtac tagatactat gaaaattaga
    18241 ttgaggcaag attataataa attaaaagta gagaataaag aagtaataaa aaaatcattt
    18301 gctcttttag aagaaggatt gaaaaaaaat aatttatctc tagttggaga ggcttgtact
    18361 ttgagtagct tagcaaatga gaatatagaa aaaaaagagt atttaaatga aataataaaa
    18421 atatcaaaaa aatatggagc atatggagta aatattgctc acagtggaac tgtagtaggt
    18481 attttaattg ataagtttat gaatgataaa aagatgatag atgccttatg tgaatctaac
    18541 ataaattctg tctataataa aatttataca caaaacataa ttaatggagg aattaagggg
    18601 gaaatagaat gaaatacata aagaatccta tgaaaataga agaaaaaagt tttgaattga
    18661 tacaagaaat aatagacgaa attagaccag attataaatt taagaataat atcgaagaaa
    18721 aaataataaa aagagctata catactactg ctgattttga ttacttagat atattaaaaa
    18781 tatcagaaga agcagttgat agtataatag atgcattaaa aaataatgca agtatttata
    18841 ctgatacaaa tatggctctt agtggtataa ataaaagaaa gttagaatca ttaggatgta
    18901 agtataaatg tttagtggca gatgatgaaa ctgtaaaatt agctaaagaa aaaggaatta
    18961 ctcgttctat ggcagcagta gaaattgcag ctaaagaaga aggaagaaaa atattcgttt
    19021 taggtaatgc tccaacagct ttatataaag ttatggagat gaaatcagaa ggtagattag
    19081 atttagatgc agttatagga gttcctgtag gttttgtagg agcacaagaa tcaaaagatg
    19141 aagttgaaaa aacagatata ccatatataa tttctaaagg tagaaaaggt ggcagtaatt
    19201 tagcagcagc aatagtaaat gctatattat atactatgta ggtacctata tggaagaata
    19261 tgtatatata gatggaaaaa aatatagaag aggatatact acaggttcat gtgcaacagg
    19321 tgcatctaag gctgctgtat atatgttgat tacaaaaaat agaatcaata ctataaatat
    19381 agatactcct aaggggatac cattactact aaaagttgat aatataaata tttctgatac
    19441 atttgtggaa tgttccataa aaaaagatgg tggagatgat atagatgcaa ctcataccat
    19501 ggatatttat gcaagagctg aaattgtagc taaaaatgat aagaacaaag ggtatcttac
    19561 tctaaaggat atagatagtt taagcaccaa tagtgagtgt aaaagtgagc tctataagtt
    19621 tattagggtt tatggcggaa ctggtattgg tgtggttacg aaaaaaggtc ttagcgtgga
    19681 tgttggtaaa cctgctataa atccgactcc acttaaaatg ataaatcatg aaataagaaa
    19741 gcttatagga gataattttg aatctatact tggaaatgat aaagttttaa aaataacaat
    19801 ctttgctcca caaggagaaa ctgtagcaaa aaaaacattt aatccaagat taggtatagt
    19861 tggaggaata tctataatag gtacaactgg gattgttgaa cctatgagtg atgagggttg
    19921 gaagaagtct ctatctatag aacttcagat gaaaaaagaa caaggcttag ataaaataat
    19981 attggttcca ggaaatcatg gagaacagtt tataagagaa aaattaaact tagatattaa
    20041 gtatgtagtt agggtaagta attttatagg ctatatgatt aaagaagctc aaagaatagg
    20101 atataagaaa atcttaatgg caggtcatat aggtaaattt ataaaagtat ctgctggtat
    20161 ttttaatact catagtaagg tagcagatgc tagaagtgag atattagtgg caaacttagc
    20221 tttaatggga gctagatacg aatttttaaa taaaataaat caatgcgtaa ctactgaaga
    20281 agctgtagag ctaataaata atagtgaata tagagaagta tataatatat taagtaataa
    20341 atgtaaggag agagtaaagc aatacttgaa tgaagattca gatgatattg atgtggaagt
    20401 aatcatattt tcaatggata agtctttatt aggtaaatcg gataatacag atgatttagt
    20461 ggaggtcttt atatgataaa cataataggt ctaggacctg gtaacttaga ctatataaca
    20521 aaaaaaggtg aaaatttaat ttccacttct gatgtattaa ttggtggtaa aagaaattta
    20581 gagtctataa aaaattttga aggagaaaaa atagttctgg attctaattt aagagaaatt
    20641 atagagtaca taaataacaa taaagaaaag caaatatcaa taatagcatc tggggaccca
    20701 ttaatatatg ggataggtag atatctatct aaaaatattg ataataagat gttaaacgtg
    20761 gtttctggga ttagttcatt acagtacata ttttcaaaaa tatatgtaga tatgaatgat
    20821 gtatatatta caagtagtca tggcaaagta ccagattttg attacatatt atcacataaa
    20881 aaagtatgta tggttacaga ttcaaagata ggaccaaaac aaataagtag agaaataata
    20941 gatagaaatc taaataaaat tattgttgta ggagaaaatc tgtcatatga caatgaaaaa
    21001 ataacaatag caaaaccaga agagataata agaatggaca attttgatat gaatgttgtg
    21061 gtgattttag atgaggaata gtgaatttat aacaggtaaa gttccaatta ctaaggaaga
    21121 ggttagagca atatcaataa gtaagttaaa tttagtaaat gctaaaaacc tcatagacat
    21181 aggggctggt acaggaagtg taagtgttga agctgcatat aattatccta atttaaaggt
    21241 tatatctata gagaaaaatg atgatgctat agagcttata gagaaaaata aaaaaaaatt
    21301 caacttaaaa aatatagaag tgataaaagg atatgctcca attaatctag ggttaaatgt
    21361 taaagttgag tctatttttc ttgggggaac aggaaataat ctggaagaaa taatagaatg
    21421 gtctaaaaaa aatctcgtta caggaggaag acttgtagct aattttataa taatagatac
    21481 atttaatcaa actttaaaac tgcttaaaaa gcatggattt aaagaaatag atgtatgtgt
    21541 tttgaatgtt tctaaactag agaaactagg aaaaggtgaa tattttaaac cactaaatcc
    21601 tatatatata atatcttgtg aaaaagggga aaatgatgat gaataaagta cattttgtag
    21661 gagcaggacc tggagataaa gagctgataa cattaaaagg atacaaatta ttaagtaatg
    21721 cagatgtagt gatatatgca ggttcacttg ttaatcctga acttttggaa tactgtaaag
    21781 aagattgcca aatacataat agtgcacata tggatttaca agagataata gatgttatga
    21841 gagaaggtat agaaaataat aaatctgttg taagactgca aacaggtgat ttttctatat
    21901 atggttcaat tagagaacaa gtggaagatt taaataaatt gaatatagat tatgactgta
    21961 ctcctggagt aagttctttt ttaggggcag catcatcttt aggggttgaa tatacagttc
    22021 cagaaatttc tcaaagtgta attataacaa gaatggaagg tagaactccg gttccagaga
    22081 aagaatcaat acaatcatat gctaagcatc agacatctat ggtaatattt ttatctgttc
    22141 aagaaattga gaaagttgtg tctaaattac tggaaggtgg atatccaaaa gatactccta
    22201 tagcagttat atacaaagca acttgggcag atgaaaaaat agttaaagga actttaagtg
    22261 atatagctgt aaaagttaaa gaaaacaaca taaataagac tgctttaata atggttggga
    22321 gatttttagg agaagagtat aataattcaa agttatatga taaggatttc aaacatgaat
    22381 atagagggta atattgctat aatctgtatt acagaaaatg gaaaaaaatt agctctaaag
    22441 ataaattctc tagtaaataa ctgtgttata tatcaagtaa aaaataaaaa aagtaattta
    22501 gttgttgaag aaacatgtgt atatacagtt caaaagaagt taagtgattt tgtaggagaa
    22561 atatttagca aatttgatta catagtattt ataatggcta caggtatagt tgtacgaagt
    22621 atagcaccat acataataag taagtttagt gaccctgcaa ttttggtaat ggatgaaaaa
    22681 ggcaaaaacg taataagttt attgagtggt catattggag gggcaaacag cttgacacag
    22741 tacataagta gtcttattga tgctaatcca gtaataacaa cagctactga tataaatcaa
    22801 aaagcttcct tagatatgat agcaaaaaaa ctaaatgcac atattgataa ttttagagaa
    22861 agtgtaaaag aagtaaattc tatgctagtg aataataaat gtgttggatt atatattgat
    22921 gaaggatatc aagttgatac taggggattt aaacttatag aaagtaagga tgagttaaga
    22981 gatagttttt caaacacata tatagaaaaa ttagttgtag taagcaataa aataaattgt
    23041 attgaagata ttgagaattt aaacctagat aataaatttg aacattgcta tagtaccaaa
    23101 aaaataataa aggtaattcc aagagatata gtgataggaa ttggttgtag aagaaacaca
    23161 gatagtgaac tgatgtataa ttcacttgaa gagtttctta ataaacaaaa tatagatatt
    23221 agagcaataa acacagttgg aagtatagaa ctgaaaaaag acgaaaaagc aataattgaa
    23281 ttatcaaaaa tattgaaggt gccatttaaa acattttcag tagatgaaat atctaaggtt
    23341 gataatcttt ttgataaatc tgattttgtt aaaaaaaatg tgggtgtgta ttcagtagca
    23401 gaacctgtag catatctttt gagcaaaggt aatttgttag ttgaaaaaca taaatataaa
    23461 ggaataactt tttcagtggg gagaataaaa atatgatata cgttgtagga attggaccag
    23521 gaagtaaaga tacaatgact ttagaagcaa taaaagcaat agaagattct gaggctattg
    23581 ttggatataa gacttatata aaactaatag aagaatttat acaagataaa gaaataatcc
    23641 aaaatggtat gaggcaagaa gttgatagat gtaaacaagc agtagaggaa gcaaaaaaag
    23701 gaaaaaaagt agcagttgta agtagtggtg atgctggaat atatgggatg gcaggtctta
    23761 ttttagaatt aatatctaaa gaagatgaag atataaaagt aaaggtaatt ccaggtgtta
    23821 ctgcaagtat tggtgcagca gctatacttg gagctcctat tatgcatgat ttctgtcata
    23881 taagtttgag tgatttaatg actccgtggg aagtaattga aaaaagattg agattggctg
    23941 ctgaagccga ttttgtaatt tgtttgtata atccaagaag taagggaaga agtgaacatc
    24001 taagcaaagc atttaaaata atgggtgagt ttaaaggtgg agatacacct gttggagtgg
    24061 taaaagatgt aggtagagaa aaagaagaaa agtttgtatg tacttttgaa aatatggact
    24121 ttgaaaaagt cgatatgact acaatggtta taataggaaa taagtctacc tatattaatg
    24181 gtgaattgat gataactcca agaggttata cagtatgatt ttaattttag gaggaacttc
    24241 agatagttta tctatatgtg ataagataaa tgaactgaaa aatcaatcat atatcctttc
    24301 agttactaca gattatggaa gggaacttgc acaacaacat gcagagaatg taattttagg
    24361 taagcttgga aaagaagata tgctaaaatt tataaaagat aataatatag taaaaataat
    24421 agatgccact catccttatg cagttgaagt atccaaaact gctattactt gtgcaaaact
    24481 attgaatata gattatataa ggtttgagag aaaatcttta attgaagaaa tagattatga
    24541 taataaattt atagtagata caattgaaga agcctgtgaa atagcaaata aaatagggac
    24601 aaatatattc ataggaacag gaagtaaaaa tttgaacaga tttatagagg aaataagtga
    24661 taaaaattta gttgttagag ttcttccaac gagtgaagtc atattaagtt gtgaaaaatt
    24721 aggtttaagt gcagataata tagtagctat gaaaggtcca tttagccagt atataaatga
    24781 agaaacatat aaacattaca atatagattt agtcataaca aaagaaagtg gaatagctgg
    24841 tgggttctta gagaaggtaa atgcatgtaa aactttcaat ataccagtaa taattataaa
    24901 aagagaatcg attaactacg aaaatgtatt taatgacata aataaaatta aagacatact
    24961 tgtgtaattt ttaggaggag aatatatgaa gaaagcctta ttagtagtga gttttggtac
    25021 aagctatcat gaaacgagag aaaagacaat agatatatgt gaagataaaa taaaaaattc
    25081 gttaaaaagc catgattttt ttagagctta tacatcaaat atgataataa ataaaataaa
    25141 aaaaagggat ggaatagaaa tagataatcc aatacaggct ttagataaaa tatatgaaca
    25201 aggatatgat gaagtaataa tccaaacact tcatattata tgtggcgaag aatttaacaa
    25261 attaaaagaa caagtagatg gatattcttc taaattcaaa aagattgtat taggaagacc
    25321 tttgcttaca catattgaag attatcagga agctgtagag gcaattaagc atcaaattcc
    25381 tcatatggaa agtaatgaag cagtagtatt tatgggacat ggaacacttc atgaatcaca
    25441 ttcagcgtat ccagcattgg aatacatgct tagggataat ggaataaatg cttatgttgg
    25501 tacagttgaa gggtatccag aaatagaaca tgtaataaga agattaaaag aaggaaatat
    25561 aaaaactgta aatttgatgc catttatgtt agttgcagga gaccatgcta taaatgatat
    25621 ggcaggagat gaagaagatt cttggaaaac aatattagaa gaaaatggat ttaacgtaag
    25681 agttcattta aaaggactag gagaaaattc ttatatacaa gataaatttg ttcgtcatgc
    25741 tgtaaaatgt gcagagaatg cgaagttcta tggtatagga gcagggccag gagatggttc
    25801 tttacttacg ataaaagcgg ttaatacttt aaagaaactg gatattctat acactccaga
    25861 atcaaaaaag ggtggagata gtctagcttt atcaatagtt agtgaatatt tacctgaatc
    25921 agtggaaata aagtctaggc atttcccaat gagttttgat gggaatgaaa aaagtttagc
    25981 ttgggacaat gtggcacaag aaattatatc agatgttaat gatggtaaaa atgtaggatt
    26041 tgttacatta ggagacccta tgatttatag tacatatgta tatataatga aaagaatatt
    26101 aggagaggta gaagtcgaaa ctataccagg aatttcatca ttttccaata tagcatctaa
    26161 tcagaatttt ccattagtca tggataaaga agctttagtg gtaattcctt gtactatgga
    26221 agatgataag atagagtatg ctttgcaaaa ttataattca atagtattga tgaaagtata
    26281 taaaaatttt aaagaaataa taaaaaaatt agaaaagtat gatttaatag aacatgctat
    26341 tttagtaagt aattcttccc aagaaagcga aaatgtgttt acagatttaa aagaagcgca
    26401 ccttgaagat aagatatctt atttttctac tatactagta aataaagata ataaaataaa
    26461 ataggtgaaa gcaatattta aaggagactt aatatgaata tagtggttgg aactaggggt
    26521 agtaatctag cgcttataca aacagaatgg gtaataaatg aattaaaaaa gaagtatcca
    26581 gaaattagtt ttgagattaa aatcataaag acaaaaggag atttaattca aaatgtttca
    26641 ctggataaaa taggtgataa aggattgttt gtcaaagaaa tagagcaaca attattagat
    26701 ggaaaaatag acatagcagt acatagtatg aaagatatgc cttcttattt agcagatgga
    26761 ctaaaatttg ctcatacgcc taagagagaa gacccaagag atgttctaat acttagagaa
    26821 ggatataaaa atttagatga tttgcctcat ggagcagtaa taggaacagg aagtaaaaga
    26881 aggaagtttc aattattgaa acaaagacct gatttaaata tagtacaagt tagaggtaat
    26941 gtggaaacta ggatacgaaa aataaaagat gaaaacatgc atggtattgt gttggcagca
    27001 tcaggaataa ttagagctaa tttacaagat aaaataagtt cttatttacc tgttgatgtt
    27061 gttattccag cacctgccca aggagcttta gctatagaaa ttagaagcaa tgatagtacg
    27121 atagagggaa tagtaaattc actgaaggat gagaatacag aaatccaaat attggctgaa
    27181 agaggttttt tagatggtgt aaatggaagt tgtcatattc caatggcagc ttattgtgaa
    27241 ataatccaag ataaaataca tcttactggc ttatatggag attcagaagg aaaaaaagta
    27301 gtaatcaagt ctatagatgg agatatttct tctcctagag agttaggttt aaagttagct
    27361 aaacttgtat tgaaggagta tgagaattat gaagggtaag gtttacttag taggggcagg
    27421 accaggtgat tataaactca tgactttaaa aggtttagag tgtataagaa aatcggatgt
    27481 aatagtatat gatagattag caaatagtag ttatttaaga gaagctaagc ctgattgtga
    27541 acttatatat gtaggcaagg catcaagtaa tcatattttg ccacaagaag atataaatag
    27601 aattatagca gaaaaagcta aagaaggaaa aattgtaact cgtcttaaag gaggagaccc
    27661 ttatgtattt ggcagagggg gagaagaagc agagacttta gtagatgaag gtatagaatt
    27721 tgaagtagtt ccaggtataa cttctgctat aggaggttta tgttatgcgg gtattcctat
    27781 aacacataga gaccatgctt cgtcatttca tgtaataaca ggtcatttga agggtgatga
    27841 tagtggagaa ttaaactgga atgctcttgc aaataacaaa ggtactcttg tgtttttgat
    27901 gggaatttca aacctagaga aaataagtga aaacttaatg aaagaaggaa aagataagga
    27961 tacacctgtt gctcttataa gttgggcaac tagatataat caaagagttg ttacatctac
    28021 acttgaaaat gtttatgaaa ctgctattaa agaagaagta aaaccgccaa ctcttatagt
    28081 agttgggagt gttgtaggac ttagagaaaa gttgaacttc tttgaaagta agcctttatt
    28141 tggaaaaagt attgctgtaa ctaggtctag aaatcaaaat agtgtattgg tagaaaaaat
    28201 aatggattta ggtggaaatc ctatagaaat acctactatt aaggtagaaa aaatacaaaa
    28261 taatattaac ttagaaaatg aaataaaaaa tataaataag tataattatc taatactaac
    28321 tagtaaaaat gccgtagaaa tcttctttga aaagatatat gaaatgaatt ttgatttaag
    28381 gatattatct aatttaaagg tatgtgctat aggttctgct acatcaaatg agttgaaaaa
    28441 aagaggaatt atagcggata tagtaccaaa aaaatttgta gcagagtcac tgtatgaaga
    28501 gttagcgcct attttaaatg atgacgataa tatacttata cctagagcag aaaatgctag
    28561 agattatctg gttgacaaac ttaaggctat ttgtgaagta acagaagtac atatatatag
    28621 aacagtaata gatgaggaga aaaaaggtga gatattagat attttaaatt ctaatgacat
    28681 agattatata acatttacta gttcctcaac agtaaataat cttgttgaaa ttataggaaa
    28741 agaaaatatt aaaatattag aaaaaataaa aacactatct ataggtccta taactacaga
    28801 gacaataaat agtttgggaa taaaattgta caaagaatct gctacatcta ctatagattc
    28861 gttagtagat ttaattataa aaaattaatt ttggaggctt gaatatgtta agaagaccaa
    28921 gaagactaag agcaagtaaa gcaatcagaa atttggtaag agaaactaag gtgaatgtag
    28981 aagacttaat atatccactg tttgtagtag agggggaaaa tataaaagaa gaaattaaat
    29041 ctttaccaga tgtctatcat ttatcaatag atatgctaga agacgaaata aaagaaataa
    29101 gtgagttggg aattgaacat ataatgttat ttggtgttcc agatgaaaaa gatgagtgtg
    29161 cttcacaagc ttttaatgat aatggaatag ttcaaaaggc aattagaaag gtaaaagaaa
    29221 taaattcaga tataaatgta ataacagatg tctgtatgtg ccaatataca agtcatggac
    29281 attgtgggat tttaactgat actggttatg ttgataatga taaatcattg gagtatttgg
    29341 ctaaaatatc tgtaagccat gctaaagcag gagctgatat ggttgctcca tctgatatga
    29401 tggatggaag aatacaagca ataagagaag ctttagatga aaatggatta gaaaatgttg
    29461 gaatcatggc ttatagtgtt aagtatgctt caaattatta tggacctttt agagaggcag
    29521 ctcattcagc accatctttt ggagatagaa aaacatatca aatggaccca gcaaatagca
    29581 atgaagctat aatagagact gaacttgata tattggaagg tgcagatata cttatggtta
    29641 aacctgcatt atcatattta gatattataa gaagagttaa agataatttt gacttacctc
    29701 tagcagctta taatgtaagt ggagaatact ctatgcttaa gtttgctgtg aaggaaggtt
    29761 tattaaatga agatgtaatt cttgaatcaa ttacatctat aaaaagagca ggagcagata
    29821 taataataac ttattttgct aaagacattg ctaaactgtt gaaaaaataa attctagtag
    29881 tataaagaat atcaaaaagt ataggaattg taattaacta ttatacagta gttttgttta
    29941 gatatttatt gaagaataat agaaactaat ttgcaatttc tatactttat ttatgtaact
    30001 aaataaaatt tggaggtaga agatgctata tcctattaat ttaaaattag atgagttaga
    30061 tgtagttata attggtggtg gagaagttgc atataggaaa tgtaaaaatt ttttagagtt
    30121 taacaaaaat gttactatag tttctaaaca aattttaaat aaattttatg atttaaaagg
    30181 aaatataaaa ataataaaag atgattataa agaaatatat ataaaagatg cttctgtaat
    30241 aattgctgcc acaaataata gagagttaaa tatggaaata ggattatatt gtagagcaaa
    30301 aaataagtta gtgaatgtag ttgataatat agaaatatcg aactttactg ttccatcata
    30361 tataaaaaga ggagatttac ttataagtgt gtctactggg ggcaagagtc cttcattatc
    30421 atcaaagata aaaaaagaaa ttgaaaagag atatactgaa gattatgagg agtatttaaa
    30481 tgtattagga gatataagaa aaaaggttat aaaaaaatac gaagataaaa gtaaaagaaa
    30541 agatgtgctt aatatgttgg taacacttga cctagaagaa cttaagaagt ttgatatata
    30601 aaaaataaaa taaaaaatgt taaaaaggtg ttgacggatt atttttaag
//
LOCUS       DAEQAF010000044        28004 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.045, whole genome shotgun sequence.
ACCESSION   DAEQAF010000044 DAEQAF010000000
VERSION     DAEQAF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28004
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.045"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            27..2039
                     /locus_tag="KRN00_002064"
     CDS             27..2039
                     /locus_tag="KRN00_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1827930.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLNYKCYDMPLDTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            2281..4194
                     /locus_tag="KRN00_002065"
     CDS             2281..4194
                     /locus_tag="KRN00_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827931.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTDNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRIEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFIEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEMEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQESILYSI
                     LLKISHKGDKNYD"
     gene            4187..6406
                     /locus_tag="KRN00_002066"
     CDS             4187..6406
                     /locus_tag="KRN00_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH1827932.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDNLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLSLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            6515..7345
                     /locus_tag="KRN00_002067"
     CDS             6515..7345
                     /locus_tag="KRN00_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBH1827933.1"
                     /translation="MNDKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWRNDDVGSRE
                     YYETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKIYL
                     PEYEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLA
                     KEVIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTN
                     YEEHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT
                     "
     gene            7335..10802
                     /gene="addB"
                     /locus_tag="KRN00_002068"
     CDS             7335..10802
                     /gene="addB"
                     /locus_tag="KRN00_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBH1827934.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            10802..14629
                     /gene="addA"
                     /locus_tag="KRN00_002069"
     CDS             10802..14629
                     /gene="addA"
                     /locus_tag="KRN00_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBH1827935.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGADFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKSDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            14675..15886
                     /locus_tag="KRN00_002070"
     CDS             14675..15886
                     /locus_tag="KRN00_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBH1827936.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            15873..19400
                     /locus_tag="KRN00_002071"
     CDS             15873..19400
                     /locus_tag="KRN00_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1827937.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYEKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHDITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKIKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            19531..20784
                     /locus_tag="KRN00_002072"
     CDS             19531..20784
                     /locus_tag="KRN00_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH1827938.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            20933..21985
                     /gene="ytvI"
                     /locus_tag="KRN00_002073"
     CDS             20933..21985
                     /gene="ytvI"
                     /locus_tag="KRN00_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1827939.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            22075..23301
                     /gene="pepT"
                     /locus_tag="KRN00_002074"
     CDS             22075..23301
                     /gene="pepT"
                     /locus_tag="KRN00_002074"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBH1827940.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            23508..24560
                     /locus_tag="KRN00_002075"
     CDS             23508..24560
                     /locus_tag="KRN00_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBH1827941.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVIEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(24937..25506)
                     /gene="yfcE"
                     /locus_tag="KRN00_002076"
     CDS             complement(24937..25506)
                     /gene="yfcE"
                     /locus_tag="KRN00_002076"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBH1827942.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIDTLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFSEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDDDELELDINLIDINTGNIININD"
     gene            complement(25531..26331)
                     /locus_tag="KRN00_002077"
     CDS             complement(25531..26331)
                     /locus_tag="KRN00_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBH1827943.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIAVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            26466..27326
                     /locus_tag="KRN00_002078"
     CDS             26466..27326
                     /locus_tag="KRN00_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1827944.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            27326..>28004
                     /locus_tag="KRN00_002079"
     CDS             27326..>28004
                     /locus_tag="KRN00_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1827945.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKF"
BASE COUNT        11740 a         2758 c         4883 g         8623 t
ORIGIN      
        1 aatttatgtt aagtaaggag attaatatga gaagaaatac aaaattatta acaacaggga
       61 ttctttcaat ggcaattgtt gcacctacaa tggcatttgc tactgaatct aatgctatgg
      121 aaaataacgc tgatttaaat ataaacttag agaaaaaaag tatcgtttta ggtagcaaat
      181 caaaagttag tgtcaaattt aaagaaaaac cagatgcaga tagcattaca ttaaattata
      241 aatgctatga catgccatta gatacaactc taaattacaa tcaatcaact ggggcatatg
      301 aaggaactat caattataac caagacccag aatatctaaa tgtttgggaa ctacaaggga
      361 taacaataaa cagcaaaaat aatcctaaaa ctttaaacag acaagaccta gaaaagatgg
      421 gattaaattt aaaagactat aatgtaacac aggaatgtat aattgaagac ataacttcta
      481 gaaaagatgt aaataaatat ttgagaaaaa cttctgcacc tattacagaa cttacaggaa
      541 gtgatagata tgaaacagca gttaaaataa gtaaagaggg ctggaaaaat ggttcagata
      601 aagtagttat aataaatgga gatgtaagta tagatggcat tatatcaact ccactggcaa
      661 ccacatataa tgcaccaata cttttggttg aaaaaaacaa tgtgcctaat agtgtaaaat
      721 cagaattaaa gcgcctaaac cctaaagata taattataat tggagatgag aatgctattt
      781 ctaaaactac tgctaatcaa attaaatcaa ctgtaaatgc tagtcaaaca cgtttaaatg
      841 gttctaatag atatgagaca tctttattga tagcaaagga aatagataaa aatcatgatg
      901 tggaaaaagt atacataaca aatgctaatg gcggagaagt ggatgcactt actatagcag
      961 caaaagcagg tcaagacaag caaccaatta tattaactga taaagatagt attacagaca
     1021 atacatataa atggttaaag agtgaggatt tacaaaatgc ttattttata ggtggtcctc
     1081 aaatgatatc aacaaatgtt ataaataagg taaatggaat aactaaagat agtgttacta
     1141 ataatagagt atacggagca gatagacacg aaacaaatgc aaacgtaata aaaaaattct
     1201 atacagatga tgagttagag gctgttttag tagctaaatc agatgtactt gttgatgctt
     1261 tagcagcagg tccattggct gcgaacttaa aatctccaat acttataaca ccaaagacgt
     1321 atgtatctgc ataccataaa gataatttag aagctaaatc agctaataag gtatacaaaa
     1381 taggtggagg attgacttct aaggtaatga gctctatagc atcatcatta tctaaacaca
     1441 atacgactcc aacagaacca ggaaatagtg ggggcaagac agttatgatt gacccagggc
     1501 atggtggttc agcacctgga aattcatctg gaggaatgat tgaaaaagat tacaatttaa
     1561 atacttcact tgcaacaact gaatatttac gttcaaaggg attcaatgta ataatgacaa
     1621 gagacacaga taagacttta tctcttggaa atagaactgc tctatctaat tcattgaaac
     1681 cagatttatt tacaagtata cattataatg gctcaactaa taaacaaggt catggtgtag
     1741 aagtatttta taagcttaaa gataaaaatg gagggactac taaaactgta gctaccaata
     1801 tattaaatag aattttagag aaatttaaac ttacaaatag aggtataaaa acaagagtac
     1861 ttcctagtga ttctacaaaa gattatttat acgttttaag aagtaatgat atgccagctg
     1921 tacttgtaga atgtgcattt ttggataatg aaaatgatat gagtttaata aactcatctg
     1981 caaaagtaaa agaaatgggt acacaaatag gtaaaggaat agaagattca ttaaaataaa
     2041 tggaaataaa aatatttaaa aacttaatgt aaatttatag ttgtaaattt atactaaagt
     2101 caaaaaatga aatataagtg tatcaatagt aagactgtat gtacatttgc acatgtgaat
     2161 gcaagtatat atacagtctt tttttgtagt taaatgcaat aatttgattg tgttttgtaa
     2221 aatacacaat atgatataat tagataatat acacttaatt taattgagga aggtgattat
     2281 atggaatatt tatttgaaaa aagtagttta aaagaatatg gaaatgaagc tttagataaa
     2341 tatagagaat tattagataa aactgataat aattcaaggt gtattctttt gttagtacca
     2401 aacaataaca caaagatacg atatgaaagg gctctaagat taaattatag tgaagaactg
     2461 aaaataacaa catatataag ttttgtgaag aaagaattag ttaaatactg gccactaata
     2521 atagaaaaat gtgatgaaat aagtacaaag gttgtatctc caacatttat atcaaatagt
     2581 ttaagtgaat atttaatagt gcaaaaagtt aaggaaaaaa ggatacaaga aggatatttt
     2641 gaagatatta caggaaccaa taaatccata gcaaatagta taatgactaa cataaataag
     2701 tctgcattta atttaattga ttttgatttt attggagaaa aaatatattc atcaaagaaa
     2761 aataaagata gtatatatag attttcatac actcaaatgg atgaaattat atcatattat
     2821 ataaattcct tactatcaaa ttcaatttta gataatgcat taagcatata tttatacaat
     2881 caatacctac ttaatgatga tttttattta aaaaacttat ttacagaagt gagatatata
     2941 attgtggata gccttgaaag ctcaagtaat gcagaagttg attttataac agaagcattg
     3001 gataatacat tacaaagtta tatatatttt gattatagta gggattattc tgtatttaat
     3061 aatgtggata tagactatat aaatgagaaa ataatatcaa aaattaagcc taaagaagaa
     3121 aatattaaaa agaaggagat tagaatagaa gatttatact tattacctgc aaatatagaa
     3181 ttaaatcaat caagtcaatt atataatgaa atgttagatt taataagtga aaaagttata
     3241 tctctcatag aagaagatgt atctccaaga gatatagcaa ttatatctcc tataaacaat
     3301 agtatattgg agcatcaaat tagagattct ttgatagaaa aaaatataga tgtttttagt
     3361 actaagaagg ataaaaaagc tgtggattat ccatatggga atgcattggt agtggctaca
     3421 tgtatatttt atggatattt agattttata aaagatgatg aatacttaag ctttttagaa
     3481 actcttttag aaataaatag gataaaagca tttaagattt ttaatgaaac aagacattta
     3541 agtattgata atatagatga acatagtcag tatcgtgata ttttacagta tattgaagaa
     3601 aaaaagaaga gtgatataaa aatacatgaa tttttaactc aattttacat agataaaatg
     3661 ttaaatttaa aagaaggtaa aaagaatgtt gggttatgta aaaagataat agctgaaagt
     3721 gagtctttta gtgaaagttt aagtctactt gggatgaaaa aagaaaagat atttatagaa
     3781 gctttaaaaa gtacaataaa cgattattac tctgttgtcg atatagaaga gttgaaatcc
     3841 aaagacaaaa tagtaataac tactccttat tcatatatat catcaaatat agatagaagt
     3901 atacaaatat gggtagatat aggaagtaat gcttggaata tgaaaataga aaaagatata
     3961 agtaatttaa ttgtacttag aaaatctttt gaagaaaaaa agatttatac aaatgaaatg
     4021 gaagaatatt ataaaaaata ctatctatac aatacagtat ataatttgtt attaaatgca
     4081 aagaaaatct atgcatttaa aagtgaatat gcgattaatg gttatatcca agagagtata
     4141 ttatatagta tacttttaaa aatctcacat aaaggagata aaaattatga ttaatataaa
     4201 ttatagagaa gaccagatac caataataaa ttacgataat ggtactatgg cagtaccagc
     4261 agtaccaggt gctggaaaaa catttataat aacaaatttg gtagctaaac tattacttga
     4321 gcagaaacat aagggtggta aaatattaat tcttacatat atgaatagtg ctgtaaataa
     4381 ttttaaaggt agaataagaa agattcttga agagaataaa atagatgata ctaattcgta
     4441 tgaagtaatg actatacaca gtttggctgt aaaaataata aaggaaaagc cagaagttgt
     4501 aatgttaagt gaggatttta acatagctga cgatttgcaa aaaagtatta tattaaatga
     4561 atgtataagt agatttagat ttgaaggtgg agaaagagct tttagatggt ttttaaagga
     4621 gcaaaaagat gaacgctgga aagaaataac tcttgaagcc tgggaaagag gtttttttga
     4681 atttgcagga aatgcaataa gtgaacttaa gtataaggga atttctccag ataaccttga
     4741 agaaatattg tcaagaggac acaaaggaat gcttaaaatt attttaccaa tatataaatt
     4801 gtatgataga aaattaaagc aaaatggatt gctagattat gatgatatat taattttagc
     4861 agaaaaaact ttaagcttag acgaagggct tagaaagaag tttcaaacta gatacaaata
     4921 tatatttgaa gatgagtgtc aggactcaaa tgaaattcaa ggtaatataa taaaaattat
     4981 atctagcgaa aataaaaacc tagttagagt tggagatata aatcagagta taacaggaac
     5041 attttcatca tcagacccta aattttttaa agaatttata aatagtgcag atttctgtta
     5101 taggatggat atgtcaaatc gaagttcaaa agatatactt gatttagcaa acactcttgt
     5161 caagtatgtt acaaaggaat ttagacagaa agaatgtaga catgctcttg aagatatgca
     5221 aataaaaact gtgccaaatg gaatgggata taaagaaaat cctaatccag aacattataa
     5281 tataaatgta aagtggtatg agagttggaa aattgaaata gagcaaactg ctagatacgt
     5341 taagggtata aaaaataaat atccagataa aagtataggt atattggttc catttaatga
     5401 acaagtgaca caagttgcta aagaacttag agagaataat ctaacctttg aagaattagg
     5461 accaaattct ttgaataaaa ggaaggttat aaacaacata gcatatatta ttgattttat
     5521 gttacattgt gatgatgtag aaaagttaat agttgtactt aataaagttt ttatagatac
     5581 tgataatgaa gaagaaataa agtatttttt agaagaatta aaaaactatt ctaccgaaga
     5641 aattatttat aattttgaat ttagtaagtt agataatgat ttaatagaat ttaaagaaga
     5701 aagtgatata tacttaagtt ttaaaagagg aatagatatt ataaaacaga tattagaata
     5761 tccaataata aggttagacc tcttagtttt gtttattggg aaaaaactta gtttagaaaa
     5821 agaagataaa gctgtactgg attatatatc tttttatata aagtatctag tatcagaaaa
     5881 tataaatatg gatttagaag atgtatataa tttattgttt gatgtaaaga acagggtgtt
     5941 taatcatata atagatgtgg tatatgagat aaatggatat gaaccagagc ccggtagtat
     6001 aacactatgt aactatcata aatcaaaggg gatggaatgg gattgtgtgt ttttactagg
     6061 tcttgttgaa tataatttcc ctgacaatat taatcaaaag tttcagagtg ataaatggta
     6121 tctaaaagaa aaatataaaa accctatggc aattattaaa tcagaagttg aagctatatt
     6181 aaaaggaagt atttcaacag attatgctca taaaacgaag attgattcta taaatgaaaa
     6241 gattagactt ttatatgtag ggattactag agcaaaggaa atgttagtac tttcaggaag
     6301 tgcttataga gatgaaagtg atatagggaa taagagaaaa gagcaaaaac catgtatata
     6361 tttaagcaga cttaatcaac atattattga aaaaaggtca aattaatata taataagtta
     6421 ttaaaagatt gcttgaaata tatctaaaag gggataaaac aatatgtaca gtaagtaact
     6481 actaaaaaat aaagttaaga gagaagtgat atgagtgaac gataaattaa aatatttttc
     6541 ttatagtcaa aattcaatta acacatataa atcatgtcca ttgaaattta aatataaata
     6601 tattgataga ataaattgga gaaatgatga tgttggtagt agagagtatt atgaaacttt
     6661 aaaaacagga agagattttc atttgatttg tgaaagatat tttagcaata tacctcttgg
     6721 aatctatttt aatgaggatg ataaaaatag taaaaagttt ttaaagtgga tggaaaatat
     6781 aaaaaaagtt gttcctattg aaaaaggaaa aatatatttg ccagaatatg aagtaaggat
     6841 gacattaaat ggggatataa tacaggcaaa gtatgattta gttgtaattg gaaataacaa
     6901 tatagaaata tgggattgga aaaccgagtc taaaaagatt gactataaac acgtagaaaa
     6961 tagaatacaa actattgttt atatgttttt agcaaaagaa gtaataccta aagttttaaa
     7021 aatggacata aatgttaaag atataaatat gagatattat caacctgaat ttgatgactt
     7081 accaattacc attttatatg atgaagaaaa acatgaagca aatagaaata aaattcaaaa
     7141 ttatataagt atgataaaaa acactaatta tgaagaacat acatacgaag acaatctata
     7201 caatgatata gaaaaggtat ataataaaga agaacgtatg tgctatagaa ataaaaagca
     7261 ttgcaagtat tgtgaattta ataagttatg taatggcaaa gaaatagatt atagtatttt
     7321 ggaggcggaa atttatggga cttaggtttg tattaggtag aagtggaagt ggaaaatcca
     7381 cctatatact agatgagatt aaaaaagaag ctcaaaaaaa tgaaacgaca tcaattatac
     7441 ttttagttcc agaacagtac acatttgagg ctgaaaatag agtaagtaag ctattcttag
     7501 gaaaagaaaa agataagtat ctaagagtta gggtacttag ctttaagaca ctaagtaata
     7561 tagttttttc tcaagtagga ggattgacag atgtaaatat aaattctagt ggaaaagcaa
     7621 tgatggtata tagagctatt gaagatgtaa gtgaagaatt aaatgtgttt tcaaaatcaa
     7681 aatcgcagtc tggttttgta agttcaatta cagatatgat atcagaaatg aaacaataca
     7741 atataagccc tgaaatgtta gaaaatatat ctggagaatt ggataatgaa actttaagtt
     7801 taaaattaaa agatataagt aaaatatata attcttttga agggaaattg catgaaaatt
     7861 atgtagatgc tcaagatatg ttaacttcat tggcaagtaa aattgaatta agcagttatt
     7921 tagatggagc ttgtgtttat atagatgaat ttacaggttt tacaccaaat cagtacaatg
     7981 tcataaagag tatattaaat aagtctaaaa gtgttaatat ctctttgact gtagatgata
     8041 tcaactatat tgggtacagt aaatctgata tgttttccag aacgaaattt acttattcaa
     8101 aattgactca attgtgcaac gaagaaggca taaaaatatt gccacaagta aatttaaaca
     8161 caggtgttat aaaaagattt gaaaaagtta aggaattaca gcacctagaa agattttata
     8221 atgcttatcc atataaaata tattcaaatc caactgaaaa tataaagata aaagagttta
     8281 acaatttata ttcagaggtg gaagagatag ccagagaaat tgtacattta gttagagata
     8341 agaatgtcag atatagagat ataaccattg ctacaagaga tttaaataga tatgattttt
     8401 tagtacactc tatatttaat gaatataata taccaaactt tatagataag aagagagagg
     8461 caaaaagtaa tccaatagtt attttaatta tttcagcttt agaaatgaag aatagacgat
     8521 atgggtatga aactatgttt aggtatttaa aaagtggact tataggaatt gataatgatg
     8581 atataaattt actagaaaat tatgtgttgg ctaatgggat taaaggtaaa aaatggtttg
     8641 atgaaaaatg ggattataga ataacacaaa gtctttcagg tcaagaaagt gaatttgaac
     8701 tggaattaaa agagaaaata aatgaaataa aaaatagagt attagagcct atagtaattt
     8761 tacaagaaaa attaagagga aaaaatagag taaaagaaat ctgtagatat atatatgaat
     8821 ttttattaga tataaatatg ccagaaacta tagaaagttt aatagtaaat tttaaggata
     8881 aaggggaact tgatgttgca aatcaatact cacaagtttg ggacatagta gtggacatat
     8941 tagaccaaat ggtggaactt atgggtgatg aaataatttc tttagaaaaa tttataaaat
     9001 taataacctt aggttttgat gaatatgaat taggactggt tcctcctagt atagaccagg
     9061 tacttgtaag tagtgtggat agaatgaaaa atccagacac gaaatattta tacctagttg
     9121 gaactactga tggtgtgttt ccgctgatta caaaggatag tggaatattg agtgataatg
     9181 atagggaaag tcttggaaac aaaggaatcg aagttgatat tgatagtaag actaggagtt
     9241 ttgaagaaca gtttcttgta tataaagctc ttacttcgac atctaagaat ttaaccataa
     9301 catatccaat atcagaccat gaaggtaaaa cgcttagacc atcaataatt atatcaagac
     9361 ttaagaagat atttcccaat atagaaaata aaagttattt agtggaagaa aataaaagca
     9421 ctgataaaga tatacttaaa aaaataacgg ttaaatcccc tacatttaat gaacttataa
     9481 acgtaataaa aaattatgac agtgatggtt acaatacaga agagattaat agtatttggt
     9541 tagatatata taggtactat ttaaaagatg aaatctatag ttctataaca aaaaaagtta
     9601 taaaaggtct tagttatact aatcaagttc ataagattga agagaaaaaa ataaggtcat
     9661 tgtataaaag taattctctt agcatatcta ggcttgaaaa atatgctgaa tgtccatttg
     9721 cttattttat acaatatggt ctaaaagcaa aaaagcgtaa agagtattca tttacaccac
     9781 cagatttagg aacttttatt cataatattt tagataggtt ttcaaaagaa cttttacaag
     9841 ataatttaac ttggagagat attgatgaaa aatatataga attaaagata ggtataatag
     9901 ttgatgaaat aattttaaag ataccaggat atatattaaa tagttctgag aggtataaat
     9961 accttgcata tagattaaag aatatgttga caactgctat aactataatt agtcagcaaa
    10021 taaaacaagg ttcatttgaa ccaatagatt atgaagttaa atttggcaac aatggaaaat
    10081 atccacctat aaaaatggtg ttagaaaatg gacaagaagt aagtttaatt ggacaaatag
    10141 atagagttga tgaatttgaa gaaggagaaa ataaatatat aagaataata gattataagt
    10201 caggcaataa gtccataagt ctaacagaaa tatattatgg tctacaatta caattacttg
    10261 tgtatttaga tgcaatcctt gaaagtgcaa aggatgaaga tataaatata aatccagctg
    10321 caatactata ttgtagaata aataatccaa tagcaaaatt taatgaagat aaagatgatg
    10381 aagaaataca agaagcaata ttaaaagaac ttagaatgaa ggggcttgta gtaaaagact
    10441 ctcacatagt taaagagatg gataaatcat taatagatgg agaaaggaaa aactctttag
    10501 taataccagt aggtcttact aaggatggaa atgtaggtaa aagtacttca gcaataagct
    10561 atgaggattt caaactgctt agaaaatatg taaggcatgc tataaaggat ttatgtgaag
    10621 aaatgttaag tggagaaata cgtatagctc catataaaca taaagatgga acatcatgtg
    10681 acttttgtga ttactctgct atatgtcagt ttgattcaac tataaaagat aacaagtata
    10741 aaaatttaaa taataagagt aatgaagaga taataaaaat gatgaaagga gatgttaatt
    10801 agtgagttct cctaaatgga caaaagagca attagaagtt atagaaagta gagaatgcaa
    10861 tttattggtt gctgctgctg ctggttcagg aaaaacagcc gtgctagttg agcgtataat
    10921 tcaaatgata acaagtagag aaaatccaat tgatatagat aagttattag ttgttacatt
    10981 tactaatgct gctgcgtcag aaatgagaga gaggataggg gatgctatag gaaaagcctt
    11041 agatgaaaac ccagaaaata aacatttaca aaatcaactt gttttattaa ataaatctag
    11101 tattacaaca atacactcat tctgtttgga tgttataaaa tcaaactttc atagaataaa
    11161 cttagaccct aatttcagaa taggagacca aactgaatgt gctattttga aacaagaagc
    11221 aatagaggaa gtatttgaag atttatatga agaaagagat gaggggtttt taaatttagt
    11281 tgaaagttat gcagaaagag gaggagataa agaagtacaa gatattatct tgggaatata
    11341 ttcatttgca atggcttctc ctgaacctaa aaaatggttg attgactcag cagaacgatt
    11401 taatattgat gaaaattttg atttttcaca gtctatttgg gctagagcta tattagacac
    11461 tgtaaaaata gagattaatg gtctttgtct aaatatggaa agggcattaa aagaagtgga
    11521 atcaatagaa gaattagaaa cttttgcaga aaagttatct gttgaatata aaaaaattgc
    11581 tgacatttca caagcatgta ataaatcttg ggatgaggca tataaaaaga tggcaagtat
    11641 gtcctttgaa aattatgtaa aaggagtaaa aagaatttca aaagatgctc cttcgtatat
    11701 aaaagaatca aaagaaaagg caaaaactat aagagataag actaagaagt ctttagaaag
    11761 tatagtaagt gctacattca ataaagataa tgattctatt agagaagaaa taaaatatct
    11821 ttataacata gttaaaccaa tatctagtgt tgtactgaga tttgaagagg aatatagcaa
    11881 taagaaaaga gaaaaaggaa taatagattt taacgatata gagcattttg cattaaatat
    11941 acttacagat gtagatgaaa aaggtaatat tgtaccttct gatatagcag ttggatatag
    12001 aaacaagttt tatgaaatat ttatagatga atatcaggat agtaatctag tgcaggaagt
    12061 actgcttaaa gctgttgcaa atacagaaac tccaaataga tttatggttg gtgatgtaaa
    12121 acagagtata tatagattta gacaagcaaa gccagaatta tttttgcaaa aatataataa
    12181 ctataatgat aaaaagggaa gttcccatag aaaaataatg ctttacaaaa actttagaag
    12241 tagagaagaa gttgtagatg ctgtaaatta tatatttgaa aatataatga atgagaatat
    12301 aggagaaatt gaatatacag aaaaagaaag actaaattta ggtgcagatt ttaatgtgga
    12361 tacagacgag aaatctatta ttggtggagc aacggagata cacctaatac aaaaagataa
    12421 taaacttgat gatgatatta taaatgataa agacgataga attaataaca aagaaaatga
    12481 aatagaggaa gaagaaaaat tagataatat acaacttgag gctagaatgg ttggaaacat
    12541 tatcaaagat ttaatgaaag tcaatgaaga tggaaaaatt caaaaggtct atgataaggg
    12601 aatagatgga tatagacctg tggaatttag agatatagtt attcttttaa gagctacatc
    12661 tgcatgggct ccagtgtttg cagatgaatt gatgaatatg gatataccaa catatgctga
    12721 tgttggagtg gggtattttg atacgattga aataaaaaca atattgtcat tacttcaaat
    12781 aatagataat ccaatgcaag atatacctct tatatctgta ttaaaatcac ctatatttgg
    12841 atttacacca gaggatttga ttgatattag agttcagagt aaagataaaa ttttttatga
    12901 ggttttaaaa agtacagcag agtatgatgg atttacagat tctcaaaatg aaaatgagtc
    12961 tgagtttata ccaagtgaag agtgcataaa caaaagtaaa gattttttaa ttaagctaaa
    13021 ggaatttaaa gaaaagtcaa tgtacatgag tacagatgaa tttatatggt acttgtacac
    13081 aaggactgga tactatgcct atgttggagc attgccaggt ggaagtcaaa gacaagctaa
    13141 tttaaaagta ttgtttgaga gagcaaaaca atttgaagaa accagtctta aaggaatatt
    13201 caactttgta aattttatag agaaattaaa aaaatctagt tctgatatgg gaagtgcaaa
    13261 aacacttggt gagaatgcaa atgttgttag aataatgagt attcataaaa gtaaaggtct
    13321 agaatttcca gtagtcatat gctctgcaat gggtaaaaat ttcaatactc aagattttaa
    13381 aaagagtatt ttatatcatc ataatttagg gtatggacct caatttgtag actatgagag
    13441 aaggatttct tttccaagta tagccaaaga agcattaaaa agcaaaataa atatagaaaa
    13501 tttatcagaa gagatgagag ttttatatgt tgcatttaca agagctaaag aaaaattgat
    13561 tataactggt tctactagaa atatacaaga tagtataaag agatggtcaa atggaattga
    13621 aagtttagat acaatatcac aatacgagat attaaaaggt aaaaattttt tagattggat
    13681 aatgccttgt gtattaagac atagggattt atctaatcta ctagaagaag taggattaga
    13741 cgcagttttt aatgttgaac ataattcaaa atggtatgga aagttgtgga ataagagtga
    13801 tattttagtg gaaaagaaga gtgatgaaga aaaagaaagt attgaagaaa ttcttgaaaa
    13861 aatagatgta gataatcctg atagtgatta ttacagtgaa atagaagaaa aattaaacta
    13921 tatatatcca tatgaattta gtacaagaaa acctgctact atatctgtta cagaaataaa
    13981 aaagatacaa aataattatg aagaagagtt aataaatact atatttgaac aaaaagtaat
    14041 attaaaaaag cctctattta ttcaaaatga agaagaaaga gaaaaaataa gtggaacaga
    14101 aagaggtaca atagtccatt tagttatgga ggttttagac ttaaaaaatg taagtagtgt
    14161 aaatgatata aaatcacaaa taagaggttt tgtttcaaaa ggtataataa cagaaaaaca
    14221 agctagtata gtaaatccat ataaaatata taaatttttt gcctctaaca taggaaaaag
    14281 aatgttgaat gctgaaatta taaatagaga aaaatcaatt tatgcacaag taaatatgaa
    14341 agacatatat atttatgaaa agcttataaa caatgacgat aaaaaacttt atgataatga
    14401 aagtgtcatg ttaagaggta tagttgatgc ttattttgaa gaagataatc aaatagtttt
    14461 ggtggattat aaaacagatt ttgtaaatga ggaaaatata aatcaaataa tagagaaata
    14521 taaaaaacag ttggatttat atgcagatat tattgaaact ttaactggta agtcagtaaa
    14581 agagaaatgt atatatttat ttggagttga tgaagctgtt tgttattagt ttttatatat
    14641 aaattaaacc taaaagatag aggaagggga aaaaatgaga tttattcata catcagattg
    14701 gcatctaggg aagtccctag aaggccattc tagaattgag gaacaagcaa agttttgtga
    14761 ggaatttata aaaatagtag aatcaaatga aatagatatg gttataattg ctggagatgt
    14821 atatgatact tctaatccac cagcacaagc agaaaaacta ttttatcaga ctgtatcaag
    14881 acttgccaat aatggtcaga ggtgtgtatt aataatttca ggaaatcatg ataatccaga
    14941 gagactctct gcaataacac ctctagcaca tgaacagggg atacttatat atggttatcc
    15001 attaagtgct acgatagaag ctaagtataa agggtttgaa ataacatatg caactcaggg
    15061 atgtacaaaa ctgaatataa atggagaaaa tattgtggtt gctacattac cttatccaag
    15121 tgaaaaaaga ttaaatgaag ttttttcaag tgaagatgag tttgagaaac aaaaaaatta
    15181 ttctgaaaag gtaggagata tatttagaag tttagaagaa aattttagaa gtgatactat
    15241 aaatatagcc gtatcacata tatttgtaat aggtggagag agtactgaat cagaaagacc
    15301 tatacaatta ggtggaagtt ttttagttga aagaaaagat ttgccagaaa aggctcaata
    15361 tactgcacta ggtcatttac ataaacaaca aaaagcttcc gaacgtttaa atgcatacta
    15421 ttctggttct ccacttcaat atagcaagga tgaaagagcg tataccaaag gggcatacat
    15481 agtggatata aaagctggtg aaaaaccaat aattgaagat gtatatttta ataattacaa
    15541 acctatagaa gtatttaaat gtaatggaat agaagaagca ctagatatat gtgagcaaaa
    15601 tcaagataga gagatttggt catattttga aataaatact gatgagataa tatcacagaa
    15661 tgaaattaaa aaaatgaagg aactattaaa agacataata gaaataaaac caataataac
    15721 atcttgttat gaacaagaaa gtgtagatat aaaagaaaag tctatggcag agttgtttag
    15781 agagttctat tcttttagta aaggtgtaga gccaaaagga gaacttatgg atttatttct
    15841 agatataata agtgaagaag gtgaatcagc agatgagacc aattagatta gaacttacag
    15901 ggcttaatag ctatattgat aaacaagtta tagactttga aaaattaatt gaaagaggtt
    15961 tgtttgggat atttggaact actggaagtg gaaaatctac aatattagat gcaataacta
    16021 ttgctatgta tggaaatata tccagaaata caaaagaata tataaacagt gtgtgcgata
    16081 aggcaattat atcatatgag tttgagatag gaagcaaaaa cactagaaga agatacattg
    16141 tagatagaac cattgctaga agcaaaacag gaacaaagac ctctaatgct agattaatag
    16201 aagtattgaa tgacaatacc caaaatgttt tagctgataa agttgtggaa gtaaatgaaa
    16261 aagtagcgca ggtcgtagga ttaacggcaa atgattttac taggtcagta gttttaccac
    16321 aagacaaatt taatgagttt ctaagattat cacgtgcaga tagaagagac atgttagaga
    16381 gaatttttaa tcttgagaaa tatggaagaa gtcttggcga aaaagtgaaa aagagaaaaa
    16441 atatacagtt acaaaattta aaagatttga aatcaaaatt aagtcaatat gatggaatta
    16501 cagaggaagt atataacaat ataaaccaag aattaataga gttaaaaaat ttggaaaaag
    16561 ataagaataa tgctttagac ctagctcaaa aatcttatga agaaagtaaa acagtatatg
    16621 aagaacaatt aaagttagaa aaaaatgaac ttagaaaaaa tgagcttgat ttaaaaaata
    16681 gtgagataaa agaaaagatt gctcttgtag aaaatgatag taacgctaaa aaggtagacc
    16741 catacataag ttcagttcaa aatctagaaa aaaagataga tgaagatagc ttcgcagtaa
    16801 gtaatttaga aaagaaatta gcaatattaa atcaggagct tgaagttaca aaaaatagat
    16861 atgaaaaaat aaacaaaatt aagaatgaag aaatccctaa attgagtgaa gaaaaaataa
    16921 gattgcaaca agcaataaaa ttagaagaag agttagtttt attagataga gagttaaaag
    16981 agctaaaaga aagtggaatt aatttaaata agactaaagt tgaattagaa aaagtaaagc
    17041 aggtgtcaga gtccagaaaa gatgcagtta ctaaatctat aaaagaagtt gaaggaaaga
    17101 ttgataaagt aaatataagt gcagaattaa aacaaaaaat atttctagca tatgaatacg
    17161 agaaagatta caacaacgta ttggaagaaa aaaatcaaaa gctaaataaa ctagaagaaa
    17221 tactcaaaga gacagaaaat ataaatttaa aagttagata tattgataaa gataagaatg
    17281 atgtaaatcg taatttagaa aatttatcac ttcacttgga tgttcttctt aaaaaatgtc
    17341 ctggtaagag tgctgattta cttttaaaat ctgaatatgt tactgaatta agaaataaag
    17401 caaataatac taaagaaaat gaaattaaga aaagcagtat acaagatgaa ttaaagataa
    17461 tacttgaaag taagtttaat actgaaaggg aagtaaattt actaaatgaa aaacttgaaa
    17521 ataatagaaa gaacagagat gacttagaaa aagaattaga agaactaaag tatttaaatt
    17581 tagcctctga acttagacgt gaattaaaag aaaatatgcc ttgtccagtt tgtgggtcaa
    17641 aacatcatga aaatcatgat ataactaagt atgatgaaaa tatatctttt gtcaaagaaa
    17701 aactggagaa attagaaaaa gaaaaaataa gtataagaaa caatatagag gaattaaatg
    17761 ctaaagtaag tgggtattta tctatagaaa aaatgaagac taaagaactt gaagatgtaa
    17821 aaggaaaact aggggggatt ccatctagtc aattattaaa aaaacttgat gaagaacaaa
    17881 gaaaacttgc attgttaaaa tctaatattc aggagtggga gaaagaaaaa gagagtactg
    17941 aaaataaagt aacattagct aaagaagaaa aaaataaaat tgaaaaagaa gaattaaaaa
    18001 taagagaaag tctgaataat tataagaaat taacaagaga tttaaacata gaaatagaag
    18061 gtttagaaaa taaatgtaaa aaaattaaac aggaatacct aggattaaag acgattacta
    18121 aagtctctaa tctattgtca aaagtaaaag aaataagaga gaatgaaaaa gaattagaat
    18181 tactaagtac tgggcattca aatttattaa aaaatagaga ctcactagat attaaaataa
    18241 gagaaaatga gagtaaacta catgaaatag agatagaatt aataaaggct agagaattat
    18301 atgtagaaaa gaaattgagt agagataata agtataaaga agttattagc ataactaaag
    18361 gtgatttagc taaaaatctt ttacataatg ttgaagaaaa tatatgtaag atattagaac
    18421 aagaagaatc aagtaagaaa aaattggaag agcaaagatt agaatatgaa aaaaacattg
    18481 ctgaaaagca caatatagat ggtagactta aaactgctaa ggaacaatat aaagaccaaa
    18541 aatcaacact aaataaacta ttggcagaaa ataaatttga aagtatatat gcagtaaaaa
    18601 gagctttatt agatactgat gcagtaaaaa aattgattga agaaatacta gagcatgaag
    18661 aagaacaaaa gttattatca tttaaaataa aatcatcaaa agaaaaatta aatggaagaa
    18721 gcataaagaa ggagtacttt gaacagttaa aagatgaaat ttataatttg aaagtagaaa
    18781 taggaaatat atccaaagat attggagcta atcaaaatca gttaataaca ttaaaagact
    18841 ctttagataa gataaatgat tttaataaac aacttaaggt agttgaacac aatgtggact
    18901 tattggaaga attagataaa tgtgtacaag gaaataaatt tgtagaatat gtttctacaa
    18961 accaattaaa atatatagcg ttggaagcat caaaacgatt ggatggaata acaaaaggaa
    19021 gatatgcact tgaaattgac tcaacactaa actttgtaat gagagataac tttaatggag
    19081 gagaaagaag aagcattgat actctatctg gtggagagac attcttgaca tctctatcat
    19141 tagcacttgc tctttcatct caaatacaat taaagggaag tgcaccatta gaatttttct
    19201 ttttagatga aggttttggt tcattagata gtgaactttt agaaattgtt atagaatcct
    19261 tggaaagatt gcatagtaat aatctaagtg tgggtataat aagtcatgtc gaggaactta
    19321 aaaatagagt tcctgttaag ctattagttt catctagtga ggctggaata ggttcaaaag
    19381 taaaaattga atatagttag aaaatatatg ttaattgaat atattatcta atatttccaa
    19441 ataatatgta attgtgatat aataaaaact aatattaaag ttatttataa ttaatattaa
    19501 tataaaaaca tgtaagtagg agtgtggtaa gtgttggaat cgcccaataa tttgattcag
    19561 attatttttt taatagtatt acttataggg tctgcatttt tctcagcatc tgaaacggcc
    19621 ttaatgtcgt tgagtaaaat cagaatcaga tatatgcaag atgaaggagt taaaggagct
    19681 aagttagtaa gttcattaat agaaaatcca aataagcttt taagttctat attggttgga
    19741 aataacgtcg taaatatagc agcaacatcc atatcaacat ctttgtttat aggattaatg
    19801 ggagaaaaag gagtggcact tgctacagct gttatgacag tattagtatt aatatttggt
    19861 gagattactc caaaaacaat agcagcaaat aattcagaaa aggtttctct attagtatct
    19921 aaacctataa aagcaattat atttatatta agaccaatag tatggatatt taatataatt
    19981 acaaatatta tatttaaatt atttggtata acaaataaag gagctaaatc attcataact
    20041 gaagaagagc taaaaactat ggtaaatgta agtcatgaag aaggcgtcct tgaaatggaa
    20101 gagagagaaa tcataaataa tgtttttgaa tttggagata tgcaagctaa aaatgcaatg
    20161 gtacaaagaa tagatatggt agctatagat atggaagata gttatgatga gataatacag
    20221 gtatttaaaa ctgaaaaatt aagtagaatg cctgtgtatg aagaaactat agatgatatt
    20281 gtaggaatac ttaatataaa agatattata tttttatctg atgaagaaat agagtcattt
    20341 gatattaaaa attatatgag agaacccttt ttcacgtatg agttcaaaaa gataacacaa
    20401 cttcttgaag agatgaaact tgaaaaaagt cagatggcta tagttgtaga tgagtatggt
    20461 ggaacatctg gacttttaac tatagaagat ttagtagaag tcattgttgg agatatagag
    20521 gatgaatatg atgaagaaga ggatgaaata caagttataa aagaagatga gtatattgta
    20581 gatggaagta ctaaaattgg tgatgttaat gaacttattg gtgtaaactt ggaatctgag
    20641 gagtttgatt ccataggagg ttttataatt ggacacctaa gcagattgcc agaagaaaat
    20701 gaagtaattg aagttgataa tataagattt tgtatagaaa gtatagaaaa aaatagaatt
    20761 aaaaaaataa gaatatatac ataatgtaat aatgttctta aatttattag aagtgtataa
    20821 atataaaaga tatcttttat atttatacac ttctttttat tttgtattca aataaaacta
    20881 gtatgaaatg gacaaaataa aaatataaat tagaagaaag gagattttta agatgagcat
    20941 actagaaaat aattttttat acaaattaaa aaacaacact atcttttttt gtatatatac
    21001 attgttattt atttttattt acaaagcgtt tccatacata gctccatttt ttctaggtgc
    21061 tataatagca cttatgatta atcctatatc acaaaagtta gaaaataagt ttcgtataaa
    21121 taaaggtatc tctactcttg ttctaagttt tcttgcagtg gctatagtca gtacagttac
    21181 tacaataata gttataaatt caatgaaaga attaatggga tttttaaata atatatctgc
    21241 taatcctgag gatataagta atactattat gtatttttta aataaaataa atgactttat
    21301 gaaatcattt caagaaatag ctaactttga tgtagaacaa ttagtaaaca aattcagtgg
    21361 tgaagtaatg caaattacaa aaaatcttct tactagtata cttggattgg ctacttctat
    21421 tccatatatt ataatattta taattacctt gtttattgct acgtacttta tagcaaaaga
    21481 ccttgataag attgaaaata gtttttataa tatgtttact gttgatgtta gaaagaaggt
    21541 aaaaaacgta aagaaagagg cagggctttc acttgttgga tatataaggg cctatacaat
    21601 acttatggct ataacatttt ttgcaatctg gggaagtttt gctttatttg gattgaaata
    21661 cggtctaata gtagggtttg taggagcttt aatggattta attccattcc taggtataat
    21721 aacaatatat cttccagtaa ttgtttatta ttttcttata aaaaattatt ttatagctat
    21781 aagtatgact gtgatatttt ttgttttgtc tttgattaga gaaatacttg aacctaaact
    21841 agtatcagta aatgttggac taaatccatt agctacccta gcagcgattt ttattggaat
    21901 ccaagtaaaa ggaataattg gagtaatttt ttgtttgggt ttggtatgta tgcatgatat
    21961 acttaagaag gtggatattt tttaattata ataattgata gattttttaa aaataaaatt
    22021 ttattcacag gtaaataaaa aaatattaat cttattaaga aagagggtat atacgtgaaa
    22081 caaaaagtag tggaaagatt tttaaaatat gtatcatttg atacaacatc taattctcag
    22141 tgtgagaact gtccatcttc agaaggtcaa agagttttag ctaagtatat agttgaagag
    22201 ctaaaaacaa tgggtgttga tgatgtgagt ttagatgaaa atagttatat aatggctact
    22261 ttaaaaggaa atactgatgg tgtggatact ataggattca tatcacattt agatacaatt
    22321 gaagatgtta gtggaaaaga tattaaacca agaataatag aaaattatga cggaaaagac
    22381 atagttttaa atgaagcgtt aaatgttatt acgtatgtaa aggattctcc agagttggaa
    22441 gaatttaaag gtgacgattt aatagtcact gatggaacaa ctctacttgg ctctgatgat
    22501 aaagctggta tagctgagat agtgactgca atagagtatc taataaatca tccagaaatt
    22561 aagcatggag atataaaaat aggatttaca ccagatgaag aaattggtag aggtgctgat
    22621 ttatttgatg ttgaaaaatt tggagcaaaa tatgcatata ctttagatgg aggaatagtt
    22681 ggagaacttg aatgtgaaaa ttttaatgct gcaaatgcaa ctattactat acatggtaga
    22741 aatgttcatc caggttcagc taaaaataaa atggtaaatg ctatacatat agctgctgaa
    22801 atatcagaaa tgttcccagc agatgaaaga ccagaaacaa cagaaggata tgaaggattt
    22861 tggcatttaa attctatagg tggaaatgtc gagaatgtaa gtatggctta tattattaga
    22921 gaccattgta aagaaaaatt tgaaaataga aaatctatta tgatagagaa tatagaaaaa
    22981 ataaataaga aatacgataa tagagtggaa ttggatttaa aagactctta ttacaatatg
    23041 aaagaaaaga ttgagccagt tatgtttata gttgatatag ctaaagaagc tatggaggaa
    23101 ttaggtataa aaccacgttt agttcctgta agaggtggta ctgatggagc aagattatct
    23161 tttaatggat taccttgtcc aaatatattt actggtggat taaacttcca tgggaaaaat
    23221 gagtgtatac cagttagttc tatggagaaa gctactaaac taattgtaag aatagctgaa
    23281 aaatatgctg aaagagttta gttaaaaggt atttaaaaat taagcattta aagttataat
    23341 agctatatca ttctttataa gtcaagctga ttataagctt gtgttgtatt taaaatggta
    23401 tagctatttt tgtaattatt tttataaaag ataattattt ttagtttagg gtatcaataa
    23461 aaagtatgaa tatcaatagg tattaacatt taaaaggggg aattgtattg aaaattaaat
    23521 ctaaaaaaat aatagcattt gcactttcac ttgggattat gttgccaagt tgtgtatatg
    23581 cagacactat tagtaaaaat caaaatgcac aggtagatat gaacaattat cttcaaggta
    23641 gaaaatctcc aaaggaggaa aaacttattg gtgaagatag atttgataca gcgataaaaa
    23701 tatctcaaag tggttggaat aatggttcag aaagggtgtt tctagttaac tcaaattcat
    23761 tgccagatgc attggcttca actcctttgg caagtaaatt ggatgcacca atactgctta
    23821 caaataaaaa tagtatacca tataatgtaa tagaggaaat aaaaaggctt aatccagcag
    23881 aagttatttt aattggaagt gaaggagcta tttcatcaag tgtaaaagaa tctcttgaag
    23941 atatggaagt attagtcagt agaatcggtg gagcagatag agaagaaaca tctttacttc
    24001 ttactagaca gctagatgat actggtgatt taggtgtctc aaaagtggca gtggttaatg
    24061 ggtataatgg actggcagat gcaacttcaa tatcaagccc agctgcaagt gataatacag
    24121 ctataatata tacaggtaag gatagcataa gaagtgaggc aaagaatttt attacacaaa
    24181 actcaactaa gacatacata gtaggtgggg agtacagtat aagtaaaaaa cttgaaggac
    24241 agttagtaaa ctcagaaaga ctagcaggga cagatagaaa agatactaat gcgaaagttt
    24301 tagaaaagtt ttatggaaaa tcaagtaagg ttaataatat gtattttgca aaagatggaa
    24361 gtggtagaga agctgattta gttgatgggc ttgctgctgg agtattagca tcaaaaacaa
    24421 agtcacctgt agtacttgca agtggaagtt taagtagtgc acagaaaagt tttataaaaa
    24481 aagtaaaggc tgataaattt gtacaagttg gtggaggtaa aaatagtaaa ccatatgcag
    24541 aagcattagc cttacagtaa tattgtgtaa atcaaaatta atatataata atagcaagta
    24601 aaccaagttg cacttcaata tatataataa aataagtaaa ctaagctatg tttcaatata
    24661 atatatagta aaataagtaa actaagttat atttcagtat aatatataat gaaataagta
    24721 aactaagtta tactccaata taatatataa tagaagcaag taaactaagt tatatttcaa
    24781 tatagcatat aataaaacaa gtaaaccaga ttctatttaa ttagaagttt aaggtattgt
    24841 acttaaactt ctaattgaga tagaaataaa atggtttact tgtttttatt atgagtttaa
    24901 taaattaaag cttattttat ttttattaaa aatttactaa tcattgatat ttattatatt
    24961 tccagtattg atgtcaatta agtttatatc aagttcaagc tcatcatcat catcagtttt
    25021 tatgatatct ataattgcga cagaatggct tccatctttt gggatagaag tacttcctgg
    25081 atttattact attaaattat catccatgta tagttttttt acatgagtat gtcctaaaac
    25141 taatatgtca ccacccattt tctttgcttt gtcaataatt tcttcttctg attctatata
    25201 accatgattc aatataattc taatttcact aaattggctc atgacataag gactctgaat
    25261 aggatgttct ataaccatct ggtcaacatc tgcatcacag ttccctttta caatcacaat
    25321 gttttctaat ttatttaatg tatcaataaa ttttttagga ttatatcctt ctggaatatc
    25381 atttctaggt ccatgatata agacatctcc accatgtaat aaaacatcac aatcagataa
    25441 tacatttaac gctttttcaa agtaaagtaa gctaccatga gtatcactca ttattcctat
    25501 tttcatatta aaaatcctcc taagtacagt ctataaaaat ttttcagata ctctatgcca
    25561 aaactcatag tttgacattc taagtaattt tatttttgca tcagatatac taacttttat
    25621 attttcgatt tgtctaaatc tgtgctcaac tccatcaacg gcaatcaata cagaatcttc
    25681 aaatctatat tctggtgcaa tctttataac agattcattt gaacatatta tacttgatgt
    25741 aaagcaccta tatgcattgg tatttatcgg atgtaaaggt gtaatctgca taagttcaag
    25801 atttatatca acaatactac ctccagcaga atagttatag gctgttgaac ctgtggaagt
    25861 agaaataatc ataccatctc cactaaaatt ttgtatatgt ttattatcaa ggcttaaatt
    25921 taggtgtata gtcctagact tgtctcctct tataacaacc tcatttacag caagcatatt
    25981 agaaccacta gtagtagtat atacttccgc attaagaagt gacatttctt gaataatata
    26041 atcttttttt gtataagctt caataaagct atcaatctta tctggtaaaa tatcaggaaa
    26101 aaaccccaga tgacctgtat ttattcccat tatgggaatt tcaggaaaat cgaaatctct
    26161 aactgttctt aaaaaagagc catcaccacc aattgatata ataagctctg tatctggata
    26221 aatatctgaa tacacttcaa agccagcatt gataagtttt ctagttaaga gttctttagt
    26281 ctcaagggac ttatttaatt ggtttgtatt tatagttata attcttttca tatattcacc
    26341 tcttcatact ttgtattata acatagtttt ataattctta atttataaat ttataaatga
    26401 cctttgtaat gaatgtgtta aaatatgtat aggtgggtat aaaaaaatgc ataagaggtg
    26461 aagatgtgtt tagcataagg aatatcacaa aaaaattagg aaaattcaag ttaaataata
    26521 taaacttaga gttaaaggaa ggggatattg ttgggattat aggaccaaat ggttcgggaa
    26581 aaacgacttt aataaaaatt ataatgggga ttattgatgc agatgaaggt gaaattgaac
    26641 tttgtaatga aactattgaa aattctccaa taagctttaa aaacaatatt ggttttgtat
    26701 atgattcttt acaattttat ccgcatttaa aggttaagga atttagaaaa atagtttctt
    26761 tattttataa gaattttgat agagaaaggt ttgatgaata ccttaataag tttgatatag
    26821 aagaaaatat gcatattgaa aatttatcta aaggtcaatc tgaaaagctt atgttatcaa
    26881 gcgcacttag tcacaatgct aagttattga ttttggatga accaactgct gggatagacc
    26941 caattgtaag aactgaaata atgcagtatt tacaagattt tgtgaaaaat ggaagtagta
    27001 gtgtaataat ttctactcat aatactgata atttaattaa aattgccgat tatcttgttt
    27061 ttataaatag aggaaatcag atttttactg ttaagaaaga attaatagaa caagaatata
    27121 agataattag ggcaaataaa gcagagttag aagcaattaa agaaagcata gttggtgtga
    27181 aagagtataa atattataat gaggcacttg ttaaagttgg agatagcttg aaagtaaaaa
    27241 gcctattgat agaaattgat aagcataagg tcaaaaatcc tactatagaa gaactaatgt
    27301 attattatgt aaatgaggtg agatgatgtt caatttaata agaaaagatt taataatagg
    27361 gattagttca gatggtatcc gtaatttaaa gtacatattg ctattttttg tgttttattt
    27421 tttccttaat tcaatttcat attatacagt aagtattgtt gttagttatt tgatatttat
    27481 aaatacgttt gagtgtgatt atgaaaatga ttcaaggatt tttataagga gtatgccagt
    27541 tagtatagaa gatatagttt actcaaaata tttattaggt gtaggattaa taatttctgt
    27601 aacaataatt gtgtccttac taagtaaatt gacatcacta gtgttcttta gaaatatggt
    27661 tttaaatgat gtattttttt ctgtaaatat atttttagca attttgacga ttttactgcc
    27721 tttaattttt aagtttggat atggaaaaat gaaagtttgt ggttttatag taagtatttt
    27781 aatttacttt gtatatggaa gtcttttgaa gatgattagt atgattgtat atcaagtaaa
    27841 gcattttaat tatagtaaag ttggaggagt atatctttca aattatgtaa ctgatatagc
    27901 taatactaag tatataaatt tatatagtat gacattttta acaataataa tttttataat
    27961 atcaatgtat ttttctatta agatttcaaa aaagaataag ttta
//
LOCUS       DAEQAF010000045        27813 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.046, whole genome shotgun sequence.
ACCESSION   DAEQAF010000045 DAEQAF010000000
VERSION     DAEQAF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27813
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.046"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(138..1328)
                     /locus_tag="KRN00_002080"
     CDS             complement(138..1328)
                     /locus_tag="KRN00_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1827946.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTVKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(1589..2020)
                     /gene="dut"
                     /locus_tag="KRN00_002081"
     CDS             complement(1589..2020)
                     /gene="dut"
                     /locus_tag="KRN00_002081"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBH1827947.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKCDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            2133..4361
                     /locus_tag="KRN00_002082"
     CDS             2133..4361
                     /locus_tag="KRN00_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBH1827948.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKYVKGKESKFDTLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(4472..4957)
                     /locus_tag="KRN00_002083"
     CDS             complement(4472..4957)
                     /locus_tag="KRN00_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1827949.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            5209..6432
                     /locus_tag="KRN00_002084"
     CDS             5209..6432
                     /locus_tag="KRN00_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH1827950.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            6436..9570
                     /locus_tag="KRN00_002085"
     CDS             6436..9570
                     /locus_tag="KRN00_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBH1827951.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLVAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            9604..10923
                     /locus_tag="KRN00_002086"
     CDS             9604..10923
                     /locus_tag="KRN00_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBH1827952.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQEEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPELKKPTVPPKP
                     IKPSLDKFSTQEEYIKALDEYNKKLDEYESAINALNQYNAEKTNYATGLTTYANYLQQ
                     KFNTENGLVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYD
                     LGLITLTDYKKQVVSNQDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(11212..11457)
                     /locus_tag="KRN00_002087"
     CDS             complement(11212..11457)
                     /locus_tag="KRN00_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1827953.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(11671..14298)
                     /locus_tag="KRN00_002088"
     CDS             complement(11671..14298)
                     /locus_tag="KRN00_002088"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH1827954.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GDVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(14359..15201)
                     /locus_tag="KRN00_002089"
     CDS             complement(14359..15201)
                     /locus_tag="KRN00_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBH1827955.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(15208..15846)
                     /locus_tag="KRN00_002090"
     CDS             complement(15208..15846)
                     /locus_tag="KRN00_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1827956.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(16282..17574)
                     /locus_tag="KRN00_002091"
     CDS             complement(16282..17574)
                     /locus_tag="KRN00_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH1827957.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(17611..17967)
                     /locus_tag="KRN00_002092"
     CDS             complement(17611..17967)
                     /locus_tag="KRN00_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBH1827958.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(18002..18361)
                     /locus_tag="KRN00_002093"
     CDS             complement(18002..18361)
                     /locus_tag="KRN00_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827959.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(18430..20403)
                     /locus_tag="KRN00_002094"
     CDS             complement(18430..20403)
                     /locus_tag="KRN00_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBH1827960.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(20625..21638)
                     /locus_tag="KRN00_002095"
     CDS             complement(20625..21638)
                     /locus_tag="KRN00_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBH1827961.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(21651..22196)
                     /locus_tag="KRN00_002096"
     CDS             complement(21651..22196)
                     /locus_tag="KRN00_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBH1827962.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            complement(22572..23441)
                     /locus_tag="KRN00_002097"
     CDS             complement(22572..23441)
                     /locus_tag="KRN00_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1827963.1"
                     /translation="MDYLKYFEKAVMYIENNLHENITVNDVAKETGYSYYHLTRLFKS
                     MFGESVGSYIKKRRLVSSTKELLYSDKKVIDIAIGSGFESSEAFSRAFKSIYKVSPIE
                     YRKNRIDVFVGKKKKLELDFMRHLVGNITIKPVIKEIEKIKVIGIKDKVILENNSLPD
                     LWEKFRKVHHIVPNTLPSKRVFGICEAISEIHLVSESMEFNEIIGLEVNSYDVIPNSF
                     VSKTIKEGKYAIFTHTGSLDNLDKTYEYIWGTWFLSSKEELDIRDDFEVYDERFLGPS
                     NVNSQIDIYIPIK"
     gene            complement(23593..24708)
                     /locus_tag="KRN00_002098"
     CDS             complement(23593..24708)
                     /locus_tag="KRN00_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBH1827964.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEIIEGQINKSNLVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAIIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            complement(24944..26080)
                     /locus_tag="KRN00_002099"
     CDS             complement(24944..26080)
                     /locus_tag="KRN00_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBH1827965.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            complement(26136..27599)
                     /locus_tag="KRN00_002100"
     CDS             complement(26136..27599)
                     /locus_tag="KRN00_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH1827966.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHDGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
BASE COUNT         9444 a         4737 c         3435 g        10197 t
ORIGIN      
        1 agagaaaata aataaaaagc aggtatcaat caaatagtaa catgtattat actatacatt
       61 actatcaata ttgtacctgc tttcatatta taagcaataa agaaaaatct atttattagg
      121 ttttataata aaaacaatta taaaactctt cttgcattta catatctact tgaatagtag
      181 ctactattta tattagatat tgttactttt tttgatgaac ctgaagatgc atgtatcata
      241 tctccatttc ctatgtatat tccaacatga cttacagaac cattatttga accttgtgta
      301 tcaaagaata ctaaatctcc acttctaagg tctcctctat ttacatatgt tccatactta
      361 ctttggtctc tagatactct tggtatacta actcctacag attttttcat aacgtactgt
      421 gtgaatccag aacagtcaaa actatttgga ccttctgctc cccatacata tggttttcca
      481 agtagtgtct ttgcaaaact tattacacta tcagctcctt gacttggaga attagtcgaa
      541 taagatggaa ttgaagtatc aacagaacct ttttcagcaa ggtattgact tgacacatat
      601 ccagtttgat tgccataact tacttttgtc catcctccac tttcagaaat acttccaacc
      661 tcagtaccat aacttaatgt agctatttta gaatgacttg tacctggtcc tgttctaacg
      721 ttcaatgact ttgctgttac aacctttgta ccctttacaa ggtcatttga actgttttca
      781 gcattttcat ttgtagagtc atttacacta gttcctaaat atttacttga aacataacct
      841 actctaccat tagaacttat ttttgaccat ccatttgact cagatatgta tccgacttca
      901 gtcccatatc ctagtgttga tattttagaa ctacttgtac ttggtcctgt tctaaaattt
      961 aatcctttta ctgttacaac ttttgtcgac ttaactgaag tatcactact ttcattgcta
     1021 cttccaaggc tatttattgc tacataattt ccatgcacat aacctgtgtt tccattatat
     1081 ttaactttta cccaagaacc ttcttttcct acgtactcaa ctttatcacc tttgtaaagt
     1141 ttccccattg attcatggtt tgtacctggt ccttttctaa aatttaccgc attccctgtt
     1201 attgttctgc tttctatact cacactctct acttcagact cattagcata tgctaaattc
     1261 cccatagtag gcattattat cgcagttgcc attatactgg ctgctattct cttttgatta
     1321 aaattcataa ctttccactc atctcctctt ttctactatc tttatttcac ttcaaaatat
     1381 aaaagaaata atcgacacta tcaaaatatc aattatttct tttatattaa tattattaca
     1441 aatttgtaac tatttgtcta tagtaatatt tgcttaccat aaattaccat gtataaattt
     1501 taatctttaa tagcctgtaa tttagtaata tagccatctt ttaccttttt ttaaaaatgg
     1561 atatattttt taactttttt gtaacttttt aaaatccagt tgagccaaac ccaccttttc
     1621 ctctttcgga gtcacttaat tcttttactt cttctatgtt aatatcatag ataggtttta
     1681 ctatcatttg agcaattttc atatgctttt caaccttaaa atcattttta ccatgattta
     1741 ttaatataat tttaagctct cctctgtatc cttcgtcaat agttcctggt gtatttaata
     1801 cagtaacaga atgctttaag gcaagcccac ttctaggtct tacctgcgct tctgtcatag
     1861 taggaagctc tatacatatc ccagttttga taagtttagt ctctccagga ggtattacaa
     1921 cctcttctat agaatacaaa tccatacccg catcacattt gtgagcaaaa ttaggtatta
     1981 tagcatcatc atttaatttt tttactttta aattgtacat cttatatctc ctttcaactt
     2041 tctataaata ttataactta aatttcgacc tcttgaagtt ttttattttt ttgtggtaat
     2101 ataattatta gtgttttaaa ggaggatttt ttatgaaact tgtacttgct gagaaaccat
     2161 ctgtggcaaa aactatagca tcatttttag gtgcaaagac cagacaagat ggttactttg
     2221 aaggaaatga ttatataatt acttatgcag ttggacactt agtatcatta tatgatatga
     2281 aggattatga taaagataaa tactctggct cttggaaaat gaacaatttc ccatttgttc
     2341 ctgaggataa gtttaaattt aagattgata gttctaaaac taaacaattc aacactgtaa
     2401 aaaagctttt gaatagaaaa gatgtagaat atgtaataaa tgccactgac aatgaccgag
     2461 aaggagaact tatagcattt ttaatatttt tactggcaaa aaataaaaaa ccagtaaaaa
     2521 gaatcttggt aaatgaatgg acaccagaag atattacaag aggtataaaa aacctaaaag
     2581 atgaagatga aatgagaaat cttcaagctg ctggatatac taggcttatt actgactggt
     2641 tgattggaat aaatttcact tctgttgcta cattgaaata cggaaatggg aaactattaa
     2701 acataggtag ggtaattctt ccaacagtta aattagtcta tgatagagat atggaaatac
     2761 taaactttgt tcctaaaact tattatgaaa tagaagggca ttttaaagct gaagctggtg
     2821 aatataaagg taaatatgtt aagggtaaag aaagtaaatt tgatacactt gaagatgcaa
     2881 ataaaattat agcttcaatt acatctgaaa ctggtaaaat actagataaa aaagttacta
     2941 tgtcaaagga atatgcacca aaacttttta gtttgacatc acttcaagga tatataactt
     3001 ctaagtattc caattttaca tctgataagg ttttaaatgt ctgtcaatct ctctatgagg
     3061 gtaatggtaa gggtggatac ataacttacc ctagaactga ttccattttc ttagaagaaa
     3121 gtttggcttc aaaagcttct caaactttag ataaattaaa ggttggtctt gaatatgaaa
     3181 ataaaattaa attttctaaa actaaaagag tttttgattc ttctaaagta gactcccata
     3241 gtgctataat tccaacttat ataattccaa aaagtttatc taaggatgaa caattagttt
     3301 atgatgccat aaaagataga tttgtagcaa attttatgcc tcctgctgaa tatgagaata
     3361 cagaaattaa gactgaagta gataattgta ctttcttaac aaaaggtaag gtgcttaaat
     3421 caaaaggata ccttgaggta tataataagg aagaaaaaaa cgatttactt ccacttgtaa
     3481 ataaagatga tgttgtagat gtgttagaaa taaaaccatt aactaagcaa actactccac
     3541 ctaaaccgta tactgaggac acacttttaa aggctatgaa aaattgtggt aaaaatgtgc
     3601 ctgaagaaga tacaacagtg ctatctggat attcgattgg aacatcagcc acacgtgctg
     3661 atgtgttaaa gaagataagt caagtgggct atgtaaagaa aaaaggtaaa tcttattcta
     3721 taacagacct tgggaaaaat ttagttgaaa tttttcctgt taaagactta tttgatgtag
     3781 attatactgg aaaacttgaa aaaagtttaa gcgatattca aaaaggaaag tatacaagaa
     3841 aagaatatct tactaatatc attagtttta tatatcaaaa tgtcaatatt ataaaacaag
     3901 atgcttcaaa aaatataaac acagaagcat atactttcga ttcaaaaact aaaaaattta
     3961 ctaaaacaaa agaaaaaaaa cagaaaaaag atgtaactaa tactgaaaaa gaagttgcta
     4021 tatcaaagga ttctaataac aaaaaagaag ttaaaaatgg tgatgaaaat caatctcttg
     4081 gcaaatgccc catttgtcaa ggtgatgtac tagaatttga caaaggcttt gcttgtaaaa
     4141 atcataaaga atgtaaattt gttatttgga aaaatgataa gtatttaagt ctttataaaa
     4201 agaaagttaa caaaacaatg gtcaaaaata ttttaaaaaa aggtgaaact aaagtaaaat
     4261 ctttaactgc taaaaacggt aataaatttg atgctacatt aaaatatgat aaaaatccag
     4321 atactggcta tttcaattgg aaaatagagt ttgacaacta aatattcata agaaaagaaa
     4381 tagcagtagt ataataatct atattatatt actgctattt cttttcttat gaagttttaa
     4441 cttttttaat agtgactttt acaatcacac tctaacctaa tttctttact atttctgata
     4501 actttaatgt atgttcatct aataaagtta gttcctcttc agaaagatta gataattttt
     4561 ttactagaga ttctttgaga atagctttta ctgcatcaaa taatttaaat gctttatctg
     4621 ttaattcaac cctaagaatc cttctatctt ttgggtcagg aaatttattg actaaaccat
     4681 gttccactaa tctgtcaata atcggagtca tatttgattt taaaattcct aaattagaag
     4741 ctatttgaga aattgatgat gaatttgatg tcataagata aagaattacc ttagcatgtg
     4801 atggagccat tggacattct tcaaaataag ctttcattat atcagagtta ttttgaaact
     4861 tttttaacaa atcgctttct ttaaatatat tattttcaag cacaaataaa aaatctaaaa
     4921 aagagtccgc tattttaagt atattgttgt tatccatatt tgtaacatcc cttcaataga
     4981 taatataata aaacattgtt gtttaatata gtataaatta taaactatta ataaatttaa
     5041 aacaagaaaa agttattgac tcataataat tataaattta taatcaaatt agagaattat
     5101 aaattgccaa taaagggaag ttttttaatt agtctaaaac taaacttaaa ttataagaca
     5161 ctttaaattc tacaacaagc tagtgtgcaa tatataatag gaggagatat gaaaagatat
     5221 ttaatagttt tcttaatgtg tagttcactg tttttagttg gatgtggaaa aacagaagaa
     5281 tctgaacctg agaaaccaat agcagtttct gttcaaaaag caataggtgg agaaattgaa
     5341 aacacaaatt ctttctcagg aactacaaag gttaaagatg aaacagctgt tactgcacag
     5401 actgttggca cagttcaaga agtgtatgta aaacttgggc aaaatgtaag aaaaggagat
     5461 gaattattga gtataagcag tccagagcta gaaaatagtg taaagcaaag taaagcctca
     5521 ctagatttag caaaagcaag ttattcaagt gccactggtg gttcattaga ggcacaagta
     5581 aatcaggcaa aaacagctct tgacaatgca aagattcaat atgaggagtc tcaaagaaat
     5641 tatgacaata ataagattct ttatgaacag gaagtcatta gtttagacca atttaaaaaa
     5701 atagaatttt ctttagagca aacaaaacaa cagttagatt ctgctcaaag agcatacgat
     5761 acagcaactt caaaaagtat acctcaagct aaagcacttg ctaaaaaaca gcttgaccaa
     5821 gctcaagtat catataattt agcaatgagt aatttagaca aattaacatt aacatctcca
     5881 gtagatggta caataacagc taaaaacttt gattcaaagg aaatgataac acaatcacaa
     5941 ccagctttta ttatttctaa tcctaatata ctagaagttg atttaaatgt agcagaatca
     6001 gatataggta aatttaagaa agatggaaat gtagatgtta taattgaaga ccaaaggatt
     6061 ttaggaaaaa tagattatgt accttcagta gttgaccctc agacatcttt atatcctgtt
     6121 aaagtacttg taaataatac aaacaacaaa tttaaggcag gtatgtctgc tcaagtaaac
     6181 ttaagtgttg aaaaagaaaa tggtgctgtt acagtaccta aaaaagcaat atttgaagaa
     6241 aatggtaaaa aatatgtata catagcaaca aaagacaata tagcaaagaa acacttggtt
     6301 caaactggaa ttgtaacaga ggataaaata gaaattaaaa gtggtgtaag tgataaagat
     6361 acagtgatta ttggagggat aagtcttatt tctgacggaa ctaagatatt tcctgtagaa
     6421 aaggagaagt agactatgaa tttaacacag acttccgtta aacgtcctct cacaatcata
     6481 atggtctttt tagtattaat agtttttggt ggtattggat ataaaaaaat gtcaataaat
     6541 ctaatgcctg atatagaaat accagttgta atggtcatga ctacttggac aggtgctggt
     6601 cctcaagacg ttgatgaaca agttagtcaa aaagttgatg aaagtttatc tgccgtttca
     6661 aatgtaaaat ctactatatc aagttcacaa gaaagtgttt ctatggtagt tgctcagttt
     6721 gaatttggaa ctaatttgga tgaaataatg aatgatgtta ggtctaaagt tgatgcatta
     6781 cagaccagcc tcccagatga tgcagctaaa ccaacagttt taaagctgga tatgaatgca
     6841 caggccatag gtcaacttgt catatctgga ggaaatgaaa atagttcaca agccttaaga
     6901 aaatacgctg aagatgtaat tcagcctaaa atagaatcca tagatggtgt tacttcagca
     6961 gaccttaaag gtggaaaaaa agcacaggtt aatgtaatag ctgacccagc tgttctttca
     7021 aattatggag ttagtttatc cactataaaa ggtgtcttat cctctagtaa taaaacattc
     7081 ccttatggtt caattactca aggtgaggat aaaatagttt taagagcgat tgataaatta
     7141 gaatccctag atgatataaa acagattcaa attcctgtaa aaggaggaaa tacagttaga
     7201 ttagataatc tttgtagtgt agattatgga tatgcagaca aagatagtat ttatagatac
     7261 aatggaaaag acagtttggt aatagatatt tctaaacaac aagatgccaa cactgtaaaa
     7321 gttatgcaga gtgcatacaa atacgtagat gaattgaata aggaaaatcc tcaatttaaa
     7381 attaaaattg ctaatgatac aagttcatac ataagtgaat caataaacag tgtaatgagc
     7441 aacttgctta taagtgctgt tatcgcattt attgtaatat ttgctttcct aaaaagtgta
     7501 agagcttcac tagttgttgc agttgcaata ccaatttcta taataggtgc tatagcaatt
     7561 ctctacttta ctggtgaaag tttaaatctt attactgcaa gttcattggt aatttcagtt
     7621 ggtatggttg ttgataatgc tacagttgta attgaaaata tatttaaata taggaaaagt
     7681 ggcagattga gtcttgatga ttgtgctatt gagggaacaa gaactgtaac aaatgcaata
     7741 cttgcatcaa cattgaccac aatagcaata ttcttaccta tcatgtttac agaaggtata
     7801 gctaaaataa cttttggggc attaggtaaa acactaatag cttcactagc attctccttt
     7861 ataggtgcaa ttacactcgt tcctagtgta tttgcaaaat taagcagagg aaaaaatagt
     7921 caaaagatgc aagaaaaaga tagtcctata tttgataagg taagtgaagc atataaaaaa
     7981 ttattaagtg tatgtttgag acatcaacgc ttagttgtaa tatcaagttt acttattttt
     8041 gtagcttcct tatttggaat gggatttata ggtatggact ttatgcctgc agcagacaag
     8101 ggtgaattat ctatttctat agaacttcca aaaggtctta gcctagaatc caatgattac
     8161 tatgtatcta tgactgagaa aaaagtctca gatattccag aaattaaaac tttaataaca
     8221 actttgacat cagattcaaa taatagtaaa gcaagtatag caattgaatt agaatctcaa
     8281 aaaaatagaa aaagaactac tgatgaaata gaaaaagaga taattgatag agtggctact
     8341 gtaccagatt gtaaaataaa tgtaagtcaa aacagtagtg ttatgggtgg agctggagga
     8401 gcagacttca cattagaaat gaaaggtcct gatttagatg tattaaaaat actgggaaaa
     8461 gaagctgaaa aagaatttag ctctataaaa ggatttagaa atgttgaaac ttctcttaca
     8521 gatacaacac aagaagctca atttactata gataaacata aggctcaaga atatggtgta
     8581 aatactgctg aaattgcagg catgttacgt acagcaataa atggtgactc cgtaaccact
     8641 gctactattg atgattacaa agtggatgta aacctaaaat ttaaagcaga tactattgat
     8701 agcttagaag atataaagca actaaaagta aactctgcaa ctggaaaaga agttcctctt
     8761 gttgcttttt cagatataaa aatggcagat ggtctacaat ctatatctag gactgatgga
     8821 gatttttctg taaatataac tgctacactt gacaatttag atgctggtac tgctacaaaa
     8881 ctagcactag aaaaaacgaa taaaatggta attcctaaag attactctat aggtgttggt
     8941 ggtgaaacag aaatgatgaa tgaatctatg gcaagtcttg gattttcaat ggtcatagct
     9001 atagcattag tttatatggt aatggtagct cagtttgaat catttagtaa accatttata
     9061 atcatgttct gtgttccatt tgcattcgtt ggagttgtgc tttcgcttct agttagtggt
     9121 caaagtttaa gtactgtcgg tatgctaggt ataatcttac ttattggtat tgttgttaat
     9181 aatggtatag ttcttattga ctacatagag caacttagaa aaacaaatcg taacaatgat
     9241 ttaattggtt tggtttcaat tggttgtgca gcaagattaa gaccagtctt aatgactaca
     9301 gcaacaacaa ttttaggtat gttgccaaca gcactatctc ttggtgaagg tggagaaact
     9361 atgcaaccac tagccatagt tataatgggt ggtctaactg tatctacact tataactttg
     9421 gtgcttatac ctactatata cttaatattt gataaatggg aaaataagtt ttcagacaaa
     9481 atgcctaaaa tatttggtaa gataacagat aaaataggaa gtataaaacg taaaataata
     9541 aagaaaccaa aattgaaagc taaagtttaa atagaatgga gggtgattgt attgaataaa
     9601 aaaatgagca aaatagttgc aattggctgt ggtgttggta taataactgc caatttaatc
     9661 ccagtttacg cagataataa tacttcttct ataaacaaag ttgataattc tattttaagt
     9721 gactcaaata aaagaacatc tgaaaaggaa attttgactg ctagagaagc tgttagtgct
     9781 gcacttaaaa atagtgaaaa attaaaaatg aaatcagaag aaataaaaat gttaaaagaa
     9841 aagttagaag tacaagagga gtttgatagt tttactggaa gtgacaactc gtttccatac
     9901 gaccaaattg gacttcttaa aaatcaaagt gaacaggcta aaggctttat ggaggaccaa
     9961 atagcaaatg atattactaa taaatttaac gatttagttt caagagaaaa tgagctagat
    10021 aagataaaaa acaatcttga aataaaaact aaagaaatta aagatatgaa attaaaaaag
    10081 gatttagggt tagtaacatc tttagaaact gaatcagctg aacttgaact tcaaacacta
    10141 caaaatactc aaaaagctaa acttcaagaa ctaaaaaaca atcaagacta ctttaagttg
    10201 ttgactaata tagatttaaa taattatcaa ttggataaag aatatagatt tgaatctttt
    10261 agagtaggtg gctcagttga ttcatatatg gaaggtaagg ttaatgaata tttaaaatac
    10321 gaccaattga ttttagaacg tacagaagaa agctttaatg ataaagatga gaacaaagca
    10381 gatttaccag atagacctga attaaaaaaa cccactgtgc ctcctaaacc aattaaacca
    10441 tctttagata aattttctac tcaagaagaa tatataaagg cacttgatga gtataataaa
    10501 aaacttgatg aatatgaaag tgcgattaat gctcttaatc aatataatgc tgaaaagact
    10561 aattatgcta ctggccttac tacttatgca aattatcttc aacaaaaatt taatactgaa
    10621 aatggtctag taacattaga agacagtaaa aaagctctta aaaaagggtt aattgatagc
    10681 tatgctcaat tacttgcttt agaagataca attcagatta ctaaaaaaca acttgattta
    10741 tcagaaaaac aattaaaaaa tactaaatta agatatgatt taggattaat tactctaact
    10801 gattataaaa aacaagtggt aagtaatcaa gatgctaaaa atagctatga cactcttatt
    10861 gtgaattata actcactaaa aaatggtata gaaaaacctt ggatacttaa tactggaaaa
    10921 taattctggt aaatagaaag attactttaa catacgtttg attaaaaaat agttatgcac
    10981 actcgtggct ttagtcatgg aagattcaga aggcaaataa tagaaataga ttagtaaaaa
    11041 tatatttgct tataaaactg tatactttta tagaggctat ctcaaaatag agataagcct
    11101 cttttttatt gtttaaatta taaaaatata tttaattcca tacaaaaaga gtgccttatg
    11161 aactaaaaag ttcattttga gacaccctca aaagcttaac tctaaattta attatttttt
    11221 atcaaatgtc tcatctattt tacatctcac catgttaaca aattcagaaa tattatatcc
    11281 tctaagtttg catccacatt taggacaata atccagtttc ctagatacca aagccctaca
    11341 actaggttct ggacatctta tttttagact ctcatctgct actttaaatc cacatcgtgg
    11401 gcatatacta cctggacgtg atgatacttc ctttccacat ttaggacact ttgtcaactt
    11461 tatcccctcc agtaaactca atttaattga tagttgaaat ttctctctac aataatatat
    11521 gcaatataat taaatacgtt tcacttacaa ctatataagt taaattttta taataaaaat
    11581 cccctatatt caatttacaa atacttaatt tgatacattg aacaataggg gattttattt
    11641 ttatttagtt acatattttg cagtctatta ttatctagga ttttttatag atgcttgagc
    11701 tgctgcaagt ctagcaattg gcactctaaa tggtgaacaa gatacatagt taagtcctac
    11761 actataacag aactctactg aagatggttc tcctccatgc tctccacata ttcctagttt
    11821 taattctggt ttaacttctc tacctaattt agctcccatc ttaactaact taccaacacc
    11881 attttggtct agtacttgga atgggtcttt ttctaatatt tcttcatcta catattgacc
    11941 taagaattta ccagcatcat ctcttgaata tccaaatgcc atttgagtta agtcattagt
    12001 accaaaactg aagaagtctg cttcttgtgc tatttcatca gcagttaaac aagctctagg
    12061 tatttctatc atagtaccta cagtataagg aacttctata ccttcttctt ttattatagc
    12121 gtcaacagtt tctactatca tttttcttat tatttttaac tcatttactt ctccaactaa
    12181 tggaaccatt atctctggag aaactttaac acctgctttg attgcttcta tagcaccttg
    12241 tattatagct ttagattgca ttacacatat ttcaggataa gttattgcaa gtctacaacc
    12301 tctgtgtcca agcattgggt taaactcatc taaatcaact attctcttct taatatcact
    12361 tacttttatt cccatagatt ttgaaagttc ttctatagtc tcatcatcat gaggcaaaaa
    12421 ttcatgtagt ggtgggtcta gtaatcttat attaactggt tttccatcca taactttaaa
    12481 taactctaca aaatcttctc tttgcattgg taatattttt tcaagagctt tttctctttg
    12541 ttctactgta ttagataata tcatttctct aactgctggc aatctagctt catcaaagaa
    12601 catatgctca gttctacata gacctatacc ttctgcacca aactctatag ctgcacgagc
    12661 atctctagga ttatctgcat tagttctaac catcatacat ttgtgtttgt ctacccagtt
    12721 cattaatttt tcaaaatttc cagttaaaga tacttctgtt ttcttaacat ctcctaggta
    12781 tacatttcct gtagaaccat ctatagaaat gtattctcct tcttttataa ctacatcatc
    12841 aagtgctctt atttctttat taaactcatc aacttttatt tctccacatc cagcaacaca
    12901 acatttaccc atacctctag caacaactgc tgcatgtgat gtcattccac ctctagctgt
    12961 aaggattcct tctgctttaa ccattccttc tatatcttct ggagatgtct ctagtctaac
    13021 taaaactact ttttctcctt tttcatttgc ttttactaca tcatcagcat tgaaataaac
    13081 tttaccactt gctgcacctg gtgatgctgg taaacctttt gctataacct tagcttcttt
    13141 taatgcctta tcttcaaatt ttggatgtaa taattggtct aattgattag gctcaattct
    13201 catgatagcc tctttttcat caattattcc agcttcaact aaatcaaccg ctacatttat
    13261 tgctgctgct gctgttctct taccatttct agtttgtagt atatataatc tttcattttc
    13321 tatagtaaac tctatatctt gcatatcttt ataatgacct tcaagtatat gagtaatttt
    13381 tacaaattca tcgaatacag ctggcattac atctgcaaga gttgatatat tttgaggagt
    13441 tcttatacct gcaacaacgt cttcaccttg tgcattcatt aaaaattcac caaataattt
    13501 attttctcct gtagctggat ttctagtaaa tgcaacacct gtaccactag tttctcccat
    13561 attaccaaat accattgatt gaatatttac tgctgttcct aagttatgag ctatatcatt
    13621 caatttacgg tatacgattg cacgaggatt attccatgat ctaaatacag cctctattgc
    13681 aagcattaat tgctcttttg ggtcttgtgg gaaatcattt tttatttctt ttttataaat
    13741 tgctttaaat tcttttacta tttcttttaa atcatcagtt gtaagttctg tatcaactgt
    13801 gtatcccttt gcttctttta ctctgtctaa tacattttca aatttatatt ttggaacttc
    13861 catagcaaca tcagaaaaca tttgtatgaa tcttctgtaa ctatcatatg caaatctttc
    13921 attttgtgta gcctctgcta agccaacaac actattgtca ttaagaccta ggttaagaat
    13981 tgtatccatc attcctggca tagagaatac tgcaccagaa cgaactgata ctaataatgg
    14041 attcttattg catcctaatg ttttatttaa gtctttttct aaagtagcta aatgctcttc
    14101 tatttctttt attatctctg ctcttatact ttcattgtta acataataat cattacatgc
    14161 ttctgttgtt atagtgaatc caggagggac aggtaagcct atcttagtca tttctgctaa
    14221 attggcacct ttacctccta gtaaagattt catgtctttg cttccttcac caaaactata
    14281 aacatactta gtttccattg ttaaatcccc cattaatctt tttattttaa tttatatcat
    14341 ttttattaat agacattatt aaatttctat ttctttgtat atctttagac cattttcttt
    14401 cattatgtct aaaattatac ctgctgtttc ttctattgcc ttatttgaaa cgtttattac
    14461 tgggcatcca attcttttca ttatctcttc tgaataatct aactcctgaa gtattctttc
    14521 taaattagcg tagtttgctt tactggacaa tcctaaagct tttaatcttt gggttcttat
    14581 ctcattcagc ttttcaggtg aattagtaag acctattatt tttttagtat ctatctcaaa
    14641 cacttcttta ggaattggta tttctggaac taatggaaca ttagctactt ttatattttt
    14701 attagctaaa tacatactca aaggagtttt agatgttctt gatattccca ctaaaattat
    14761 gtctgcttga agaacacctc tagggtcttt tccatcatca tatttcactg caaattctat
    14821 agcttcaact ctcttaaagt aagattcatc taattttcta attataccag cttctctttt
    14881 aggttttctt cctgttctct tgcttatttc tcttagtata tctgtcatta aatctataca
    14941 actaagacct tctctttcgc aatatctttc aacaatactg cataattctt catcaactaa
    15001 tgtatataca attaaagcgt tttcagcttt tgcattctcc aaagtttcaa gtagtactcc
    15061 tttattaatc atgtatggaa atctttttat ttcataagtt tcattcacat aaaactgaga
    15121 catacatgcc tttgcaactt gttgtgcagt ctcccctact gaatctgata ctgcatatat
    15181 aattaggttt ttcaccagca tacctcctta attgtcaact atttctaaga atagcttagt
    15241 tatgttggtt tttgatattc tcccaacaac tctcatatga tttttgtctt ctcccttata
    15301 ttcaacaatc ggaatcgaat ctacttcatg ttctattatt tttcttgaag ctaataaaac
    15361 acttgctcct ttagttaaag tgactacatt tggagttctt gtcattatca tacctattgg
    15421 cattttattt atatcagaac ctcctatagt tgcttttagc aagtcttttc tggaaacaac
    15481 tccacataac tcttcattct catctataat aactatactc cctacatcag ataaaaacat
    15541 agtgactatt acatcatata tactttcatc cttcttagct agtacaggca tgctcattat
    15601 atcctctact gttttttctt ttacactttt accaattaaa tttatttcac taactcctga
    15661 ataaaaatat ccaacttttg gtcttgcgtc taatattcct gtcattgtta atatagctaa
    15721 atcagatcta agtgtagcac gagtcacatt caagctggag gcaatacttt cactcgttat
    15781 tggttcattt tccttaacta tatctataat ttttagttgt ctttcattaa gctgaataat
    15841 aatcaccttc tttcattgtg ctatactttt tatcttttcg catcttatat agtatattat
    15901 ataactatat ataccattct gtaaacagat tttttattga atacgatata ttttttacta
    15961 agttctctcg cttaaagata tttattatat attaatgggg gatatttctt taattaatag
    16021 aactatatta gtattacagt taatattata atacataatt ggtcatttta attcatttta
    16081 tattaaaatt tttaataata ttatttcaat gtgaatataa aattgcagaa ctaattcaaa
    16141 ataattttta cgactacaaa taacctataa tatactttta aagaaagtat cctaacaaga
    16201 atatataaaa atttaaaagg gttgatttaa aaataaccat caaccctttt tactaatatc
    16261 tatttatatt accatcaaat cttacccaaa tattttttct tgcaattgtc ttaaatgata
    16321 taaagtagta tctttttcta tctctaccat atcgtaagtt ataacttcac cttttttaat
    16381 atcttttaca actttagtct ttttacttat caaaccaata ggtacagcat tcatagcctt
    16441 tgctacatcg tatttttcta tagtaccata gcatgtatat gctccatagc catccataaa
    16501 ctcacctttt ttcaaatctt tcttagctat agtcataact tctgctacta gtccagcttt
    16561 aggtactatt gtagccttat ggtctaagac tgccatagct gctgataaag gagtctctaa
    16621 actacataaa tgatatggtc tatataatat gtaattaggt ccatcaccca tacttaaata
    16681 ttttagttca tcattaactg cttttaattt atgggctact actacgaaaa ctccaggtgc
    16741 tataccattt acaaaatcaa ctacaccata attatctaat actccacctt cgctttttaa
    16801 tgcatatttc ttaggtactt cattaactgt agcttcaata ccatgaccac ctcttacatc
    16861 aggcacaaat ccagttgcat tacacattaa agccatttct accattgttt tagttccttc
    16921 tttaaaagaa gctatcatat gaggtgaagc tccttttctt tctgcttctt ctctaactgt
    16981 atcaggatta caatctaaat ctaatttatt atttttacct ttacctatca ctctaacttc
    17041 aaaccccatt gcatctgcaa aatcaaataa ttccattact gcacctggct catctcctgc
    17101 agaacctgta aatattactc cagcatcatc tgctaatttt ttaagtattg gtccaacaac
    17161 acaatcagtt tcagcattta acataactat atgtttttta tttaaaatag agtttaatgc
    17221 tatctctgca ccaattgcaa tacctccagt tgcatctata actacatcta ttgacttagt
    17281 tttacaagcc acaagaaaat cattacatgt caatactttt ccttcttgta attttatttc
    17341 tgcatccttt tcatttgtta cattatctat aatttcttca tctattcctg catcagtaaa
    17401 agctttatga gccaactcca aatttatatc tacaacaata gaagcttcaa tacctttcat
    17461 atttgccatt tggcttacca ttccatttcc catatgccca gctcctataa gagctacttt
    17521 tattttttta ccttcctctt ccaattttgc aagttttctg tttaaatcta acataccaat
    17581 tcctcctgtt ataataattt tattttcaaa ttaagaaata gttattaaat ctccaatagt
    17641 tatatctgga tttcctattt ccacatgtat ttctcctggt aaatttactt cacattttcc
    17701 atcaaatttg attgtacaat gcccaatttc tctaagagtc ttctgagcaa tatcaccaac
    17761 tgaaactata caataatctc tattccctat agtaagtgta tctcctattt caacatcact
    17821 ttttaacgtt gctattgaat gaattacaga tatatccttt aagtcgtcat cattaatggt
    17881 ttcatcatat ataataagac aattgctttc atccattaac tctttaacta aactgcctat
    17941 cccacttatc ttaacttcat atttcatgac attcctcctg ataatttata tttatattga
    18001 gttaattaaa agaaacattt attttttctt ttataaattt tatagcttgt acaatactct
    18061 cttcatcttt aaatttttgc tctgcactat atatatctaa tccttctatt tcttcaatct
    18121 ctttaaattt agccattact gtacgtcctt ttaaaatttc tccaaacttt ataaacccat
    18181 ctgaatctga agatataatg gctatacttc ctttagaaaa atagcttttc tttttgcctg
    18241 tagacactat atcacccttt tttttagctc tatttaaagt tttaaaatac aatttattct
    18301 gcttcattat aaatatagta tttaaaatat aagcaacaaa taaaatcact aataatttca
    18361 tatttataca ccttccaaaa atcacattat ttttaaatct gtataacaac tataaatgct
    18421 gtacaatagt tatataaggt ttttaagtaa caccttttta aattctaaaa aagttctaca
    18481 tttacttatc ttattcgtta attttacatc ttggcctatc tttaaaactt cttcataaat
    18541 ttttactaat aagtctgagt ctatcttatt ctcacatgga aacattgtca taagaattat
    18601 ttttatactt ctatttgcat attctattgg ttcttctaaa attccaactg ccattaaaaa
    18661 cttatctgat ttttcattta cagaatgagg aaataataaa cctttatcaa atactgtggg
    18721 agatttttct tctctattga ctatattttt tctaaactta tcatcaatgc atcctaaatc
    18781 cataagatgg tccatcattt tttctaatga agcaagtata gtcttttcat ttaatatcat
    18841 aaatttatct tcatctaaca aattatttat tagtaaattt gtagaattag tagtgtcaat
    18901 attcccttct cttaggcaca atactgtttt taattgttct cttagtttgt tttcatcaaa
    18961 tattgtattt atttttaata ctattgtatt tatatttgat gtgtctaaat caatagttgt
    19021 aaaaactata tcatattcat ctaagttaat atttctcaaa ttaaaacttg aaagagtatc
    19081 aattttagga ttatttccta tcagtttttc tactcttatt ttcaatagtt ttgctgttcc
    19141 tagacctgta ctacatataa ttgctatttt ttttattgaa tagaatctac tgctatttct
    19201 ttctaaatat ccactgaaat ggattgctat atatccaatc tcatcttctg aaacttctaa
    19261 gttatacttt ttctctatta cttttcctgc tatttgtgct aatttaaatg gaagtatata
    19321 attttgctta atctcttcta acaaaacatt ttttaacttt atattaaata atagcctgtt
    19381 taaagtaaaa ctaagatgat atcctagacc tactcttaat tcatcctcat ttataaaaat
    19441 acccatatcg acatatattt gattaaatat attttccatc aactcatcaa tgtttttact
    19501 aattctacta ctatttaaag cacattctga tgctggtgca tttccactaa ctaacggtat
    19561 agttaaataa ataatttctt catcatttaa agtacattca aacattcctg atattatatg
    19621 ttttatttcc ctagcaataa agtattcatc atatgattta agtaaatcaa actttacatc
    19681 ataatctttt actttctttt cttcttttac tctatagact aaaactacta tgtagttaat
    19741 aacttctctt aacatttcat ctgtaacata aaaattattt tttttaaata aagtcaatag
    19801 tttttcttct aaatttatga tttcttcttt tttgattcct ttaaaatact ttgaattact
    19861 gaaatctttc cttgagtttt tatacaactg atttaatata aacagtctaa tatcaagttc
    19921 atttccattt aatttcatac ctgtattctg ttttttaatc aagtttaaat tatatgaagc
    19981 caaaactttt tctacatact ggaaatcatt tactaaagta gttcttccta cacacatctc
    20041 atcagctaaa ctatcaagtg taataaatcc atctagttct atcaagtaat ttagtataaa
    20101 ctctactcta tcttcttttg aatttaatga aaatacattt tttctattca tatcaataat
    20161 cttattgagt atctgctcat cttttatttc tagtttatag ccttgaccct ttatatattt
    20221 gattactgct atatcattac ctaaatcttt attcaattgt tttatatacg tccttacact
    20281 tctagttgtg acattcaatt catttgctat tgagttaata ctcacaaact cttttttact
    20341 acacataatc aatatcttaa atatcttgcg gtcaatagaa ggaattttct cagttacact
    20401 cattttgtat ctcctccttg atttcattct agtacaaatt tgaaaccaaa ttaatacata
    20461 aaatttcact ttaataaagg aaaatttagt attaatctaa ctcgataatt acagctaatt
    20521 aatagtataa aagctagtct ttcattaaca aaaaatcttg actagcttaa atttatattt
    20581 acaattttat taattaattc caagccttat attgacatta aatattatct caatgcaaat
    20641 actgcaactc catatgcaat aataacagct attggaccag ttattaaacg agagtaaaat
    20701 aaagctggaa caccatactc tacagtttct ggttctgctt ctcccaaact taatcctact
    20761 ggtacaaaat cacatccagc ttgcccattt attgcaaata aagctggaag tgctaaatat
    20821 gctggtattg caccaagacc aatttgtgta cctacaagag tccctactac ttgagctata
    20881 actgcaccag gtcctagtat tggtgataag aatggaagtg tgcaaattac tgatataatc
    20941 aataatccac caatattacc tgcaagtgga gatataactc ttgcaatcca gtctcccagt
    21001 ccagatgcta aaataattcc cataagcata cttacaaatg ccataaatgg tattacgtta
    21061 ttcattacca tttggatagt atctcgacct gcatcataaa attttgatac tacttgccct
    21121 gccccttgac caatagaaag tattatgttc tttttagcat attcaccttg tgcttttgac
    21181 ttaacctcat cataattatc aggctttcta atagaactct tattttcgct tttattttct
    21241 tgagattttt gtggcatatc ttccccatct acaacactta tacagttagg attaacatct
    21301 gatacataat attcttctgt tataaatttt gctaaaggac ctgtttttcc aactggattt
    21361 acatttattg taggtatttt tttctttgga taaactccac atctagcagt tccaccacaa
    21421 tcaataataa ctactgctac ttcttcatca gaaactccag ttttaaatcc atctacaatt
    21481 tcacaaccca gtagttcttt tatttttaat gttacttcat ggataccgcc agcagtcatt
    21541 gatagtatct tatttctatt cccttctttt tttatataca aaggacctcc ccagcctgaa
    21601 gttccctttt ctatttttaa tattttattc tcctccattt tatctacctc ctaagcctta
    21661 tttgttgctc tattttttct tgttagaaaa gcatacattt tttctgttac tatacctctt
    21721 ataaaaatta caattagacc aactataaaa taccacaatg ctagtgtagt agtttcttta
    21781 cctaaagtag tcaaacctgc agatattccc aaccatacaa aaagttctcc tgcatttgca
    21841 tgtggaaaaa gacctgtaat tggatgtaca aatgaaactg ctgcatcata aaatcctgct
    21901 ttgtgctctt cttttaaaaa tctaccaaat gtatagcaca taggatttcc caagaaaaat
    21961 actgatacta atggaagtag aatatatctt gtaaaagagt tctttcctag cttagaagcc
    22021 caattattaa ctctttcctc accaattatc ttaatcaaag agttaatagc taccattaat
    22081 acaattagcg ttggaagagt acctgaaaca agacctataa attgttctcc ccctttctga
    22141 aacaaaccga taaaccactc tgcaccttta cttagacctg taataacgtt ttccataaaa
    22201 ttataacctc cctataatat ctttaaattt ttaattttac tgcttaccat aaattttaca
    22261 aattacatct tttttctgta ctatatgcta atattgtaaa tgttttttta ttaatatcat
    22321 tttaatataa tatttttgat aaataaatac atcttttttc aattttataa aggaaaaaat
    22381 tgtactaatt agaattttca gaaatataca attcttattt cgactatatt ctaaattctt
    22441 cttagaaatt taagaactta tttttatttc ttttattatt aaaattatct aaatctgata
    22501 aaaataaaaa atagatgctc ttttacgaac atctatttct taatcaaatt attttttagt
    22561 tttcttatag attattttat aggtatataa atatcaattt gtgagttcac attactagga
    22621 cctaaaaatc gttcatcata tacttcaaaa tcatctctta tatcaagttc ttcttttgaa
    22681 cttaaaaacc aagtacccca tatatattca taagttttgt ctaaattatc taagctacca
    22741 gtatgagtaa atatagcata ctttccttcc ttaatagttt ttgaaacaaa tgaatttgga
    22801 atcacatcat aactattaac ttcaagtcct attatctcat taaattccat actttcacta
    22861 actaggtgta tttcagagat tgcttcacag attccaaaaa ctctctttga tggcaaagta
    22921 tttgggacaa tatgatgtac ttttctgaat ttctcccaca agtcaggtaa tgaattattt
    22981 tctaaaatta ctttatcctt tatacctatt acctttattt tttctatttc ttttataact
    23041 ggtttaatcg ttatatttcc aacaagatgt ctcataaaat ctaactctaa ttttttcttt
    23101 ttaccaacaa atacatcaat tctatttttt ctatattcta tagggctaac cttgtatata
    23161 gatttaaatg ctctgctaaa tgcttctgaa gattcaaatc cactaccaat agctatatct
    23221 atcacttttt tatcactata taaaagttct tttgtactac ttactaatcg tctttttttt
    23281 atataacttc ctacactttc accaaacata gacttaaata agcgtgttaa atgataataa
    23341 gaatatccag tttcttttgc cacatcattt acagttatat tttcatgtaa attattctca
    23401 atatacatta cagctttttc aaaatacttt aagtaatcca atatggcacc tctcttctac
    23461 ttaaactctt taaatatgta aaatagcact attttttact atactaaaat attataacta
    23521 attcaatacg ataaataaaa acttttagtt gatttatatg tcctaattat ttagaataat
    23581 tgaatacatt ttttattcaa tgaaatcaaa aaagtcagat ggtgcttttt caatatttat
    23641 gtttatcctc tgtgttatag atttaatgtc attttttaaa tagtagctct cccatttatt
    23701 ctctagtcca ccccataaaa tattaaactt tcctatattt aaatccataa ctatactttt
    23761 taaagttcca aaaaaatcat tatagtaatt acaagataag ccatttggat attttgaaga
    23821 caataaattc attaactctt tctctccaat ttttttagac ttatttatat attctttaat
    23881 taatttatat ctatgaatag aatttttcat tgattgtggc tctaatttat gaagtttatc
    23941 aatatgtgta tgattagtag agtgtaaaaa atattctctt ttactttcta aactattgat
    24001 tatatttact tcttttttcc catctaaagt ctccacaagt gcaatgtttc cagacttatc
    24061 tgcaagcaat aaattaatat tgtatgcaat tggcatatcc tttaaatatt ctaatgcttc
    24121 atctacatct ttgcaatttt ctaacaaata tctaataata gcccaaaact gtaaacctac
    24181 aattgctggt tttcttaaac catctgaatt gcctacagga ataccacatg atgactgact
    24241 tacacctaag ccacattcat tcataccttc acctcttcca aattgcataa cggtagtacc
    24301 tatatgtgca tattttccat ttaccttagt tttacataaa acaaaatcct ccatattgtg
    24361 tgagaaatcg aaattacgtg caaatagtac atgcccattt tcagttaatt ctggtgctaa
    24421 tgcaacttga ctacaacctg gtttaagata agtcatagta taatataaaa tttgattaca
    24481 attcacttga attgcatcag caaaaccttg caattcttca ttaagacctg gacaatattt
    24541 atcaaacaac tctatcatct ctttttcttc ttttttgctt accagattag atttattaat
    24601 ctgaccttct attatctctg gcatattagc aaccaattct cctagtctgt atcctatctc
    24661 ataatttgta ccactcaatt caatatttct tacttctaaa gtttccatat gtacccctcc
    24721 tatatatctt ataatcgatt ttatcattcg aattgtaatc attcatgata ttttgtgcta
    24781 caagttaaaa aaggtcatat aaaaacagat aagcctcttt ttcattgtta aaataataaa
    24841 aatatattta atttcataca aaaaagagtg tctcataaac taaaaagttc attttgagac
    24901 actcttctta ttttaaagag tataattaaa aatagtctaa gttctactct tccttcattt
    24961 ttttcaataa ctctggattt tcaaataaat taaatcctgt taaagctaat atttttatac
    25021 catcaattac tctatctttt gcatatgaat ttatagaagc ctccaaaaat tcttttgtat
    25081 gtagttcttc tccattttca gaaaacttca tcaaaggatg tatacatggc attatttgac
    25141 ttaaatttcc catatctgtt gaacctaaca ttacttgttc atcttcatat attccaaatt
    25201 cctccataat ctttgtaaat atgtctacca aaactttatt ttcatttaat ccttggcaag
    25261 ttggttcaaa gtgataaaat tcaagttcac atccagtggc tattgcagca cctctagcac
    25321 aatttttcac tttttctact acttcatcaa agtaattttg ttcttttgcc cttatctcta
    25381 atcttacttt tcccatatca ggtattacat ttgcagcagt tcctgcttct agtataatac
    25441 catgtattct cgttccatct actaattgtt gtcttagtgc atttatatta ttatatagta
    25501 atactactgc atctaaagca tttattccgt tatatggctt agctcctgca tgagatgctt
    25561 ttccagtaaa tatgaaatct agacctccta ttgctataat ttcaggtgtt acacaagttt
    25621 ttgaatttgg atgtatcatc attgctgcat catagccatc aaatacacca tgttctatca
    25681 agtaaggctt tccatctcca gtttcttcag caggtgttcc aattatactt acttctccct
    25741 tgtaagtatc cagtatactt gaaagagcta ttccagctcc aactcccata gatgcaatta
    25801 aatgatgtcc acatgcatgt ccattgcctg gaagagcatc atattctgct ataaatgcta
    25861 ttttaggacc atctccattt ttcttggttg ctttaaaagc tgtagccata cctgccaagt
    25921 tttcctcaac atcaaaaccc tcttctctta aaaattctga tattttttta gcagatttat
    25981 attcttgcaa agcaatttct ggttcatcat ataaagattg acatagccct agaatttttt
    26041 ctttctttga atcagccact tgtattattc tttctttcat accaatctta cctcccacta
    26101 aatttattta gtaattttta tattttatta taactttaat ttaactcatg cttatcctct
    26161 tttaagtatc tattttccca aaactcagca tttcttatat ctaactctat agggttaaaa
    26221 gttctatcac tcctttttat tcccatcttc ttctgtctta tataatcata atatgccttt
    26281 atagctggtt tttttagtgt aaagatggca attaaattta tatatgttaa tacacctata
    26341 catatatcac ctaatgccca gcttgtaagt ggttctataa aacaacacat tgctgcacat
    26401 gctataagca taaatctaca gacattaatt atgtactttt catgtttttc tgctttaatt
    26461 ctagttacta agtaagatac attagtctcc atcatatatg agaaggctaa taaagttgta
    26521 aatgtaaata ataataaaac tattgctata aaaatatcac ctaattgtgg atgtaatgta
    26581 tttattgcac tctgtacata ttgtggtccc ggttctacac ctggtagtgc tgtgcaaaca
    26641 cctgtaacat tatacattcc tgttattaca atcataatac ctgtagccat acatattaat
    26701 aatgtgtcta cataaacaga aaatgcttga actaatcctt gtttggctgg atgacttact
    26761 tctgctgctg ccgcaccata agtcccagaa ccttctcctg cttcatttga gtatatacct
    26821 ctttttactc cccaagatat tgctgaacct agcattcctc caaaaactga accaaatcca
    26881 aatgcagatt taaacattgt tacaatagcc tctggaacta aactaatatt tgttataatt
    26941 attactaatg tcataataag gtatgctcca cccattatag gtactacttt ttcagcaaat
    27001 aaaccaatcc ttttaattcc tccaaaaatt attatcgcta atgcaataga agatgctact
    27061 gctattgtca tttttgaaaa tccaaatgct tgattcattg ctagatataa agtgtttgat
    27121 tgtgtaccag gcataaaaaa tgtataactt attattgcaa ctattgaaaa taaaactgaa
    27181 cactttttcc acccaagacc tttttcaaaa taatatggag gtcctcctct atactgccca
    27241 tcatgctcat ctttatatat ttgagctaga gtagattcta caaatgcagt tgctgaacct
    27301 aatgtagcca ttatacacat ccatactaat gctcctggac ctcccattgc tattgctaca
    27361 gctacaccag ctatatttcc agtccctatt cttccagcca tagatgtagc aaaaccttga
    27421 aatgatgata taccaacatg agaactatct ccttcaagca agagagtaaa catttctttt
    27481 acatctctta tttgaaaaaa ttttaatttc aatgaaaaat ataatcctat acacaaacac
    27541 attgcaacta atacgggtga ccaaacaatt ccattaatgg tgttaactaa atcggtcact
    27601 taactcacca ccattcattt tatatttata gacaataatt taaacagcta tatttcaata
    27661 ttttatataa tctttatatt aatatatcta aaaaatctac cttctattta tttatattat
    27721 ctttaatcta caatctacaa atatttattt ctaaaatcaa gagtattaat catatctaaa
    27781 cataaattta taaaattttt aacgacgtgt gtt
//
LOCUS       DAEQAF010000046        27414 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.047, whole genome shotgun sequence.
ACCESSION   DAEQAF010000046 DAEQAF010000000
VERSION     DAEQAF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27414)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27414)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27414
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.047"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            29..571
                     /locus_tag="KRN00_002101"
     CDS             29..571
                     /locus_tag="KRN00_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827967.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            650..1117
                     /locus_tag="KRN00_002102"
     CDS             650..1117
                     /locus_tag="KRN00_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBH1827968.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            1826..2962
                     /locus_tag="KRN00_002103"
     CDS             1826..2962
                     /locus_tag="KRN00_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBH1827969.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            3021..3803
                     /locus_tag="KRN00_002104"
     CDS             3021..3803
                     /locus_tag="KRN00_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBH1827970.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            3822..4832
                     /locus_tag="KRN00_002105"
     CDS             3822..4832
                     /locus_tag="KRN00_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBH1827971.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            4851..5648
                     /locus_tag="KRN00_002106"
     CDS             4851..5648
                     /locus_tag="KRN00_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBH1827972.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFIDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            5746..6591
                     /locus_tag="KRN00_002107"
     CDS             5746..6591
                     /locus_tag="KRN00_002107"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBH1827973.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            6678..7853
                     /locus_tag="KRN00_002108"
     CDS             6678..7853
                     /locus_tag="KRN00_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH1827974.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            8048..8950
                     /locus_tag="KRN00_002109"
     CDS             8048..8950
                     /locus_tag="KRN00_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBH1827975.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLAKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIYEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            8964..9968
                     /locus_tag="KRN00_002110"
     CDS             8964..9968
                     /locus_tag="KRN00_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBH1827976.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(10112..10339)
                     /gene="acpP"
                     /locus_tag="KRN00_002111"
     CDS             complement(10112..10339)
                     /gene="acpP"
                     /locus_tag="KRN00_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBH1827977.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            10511..10936
                     /locus_tag="KRN00_002112"
     CDS             10511..10936
                     /locus_tag="KRN00_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827978.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            10984..11190
                     /locus_tag="KRN00_002113"
     CDS             10984..11190
                     /locus_tag="KRN00_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827979.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            11372..11551
                     /locus_tag="KRN00_002114"
     CDS             11372..11551
                     /locus_tag="KRN00_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827980.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            11585..11785
                     /locus_tag="KRN00_002115"
     CDS             11585..11785
                     /locus_tag="KRN00_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827981.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            12038..13054
                     /gene="ccpA"
                     /locus_tag="KRN00_002116"
     CDS             12038..13054
                     /gene="ccpA"
                     /locus_tag="KRN00_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBH1827982.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(13177..13575)
                     /locus_tag="KRN00_002117"
     CDS             complement(13177..13575)
                     /locus_tag="KRN00_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827983.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            13787..14692
                     /locus_tag="KRN00_002118"
     CDS             13787..14692
                     /locus_tag="KRN00_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1827984.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNKGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            14807..14987
                     /gene="ssrS"
                     /locus_tag="KRN00_002119"
     ncRNA           14807..14987
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KRN00_002119"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            15170..16387
                     /gene="cdeC"
                     /locus_tag="KRN00_002120"
     CDS             15170..16387
                     /gene="cdeC"
                     /locus_tag="KRN00_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBH1827985.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNAECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(16487..17809)
                     /locus_tag="KRN00_002121"
     CDS             complement(16487..17809)
                     /locus_tag="KRN00_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBH1827986.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPELNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(17860..18654)
                     /locus_tag="KRN00_002122"
     CDS             complement(17860..18654)
                     /locus_tag="KRN00_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH1827987.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            18764..20209
                     /locus_tag="KRN00_002123"
     CDS             18764..20209
                     /locus_tag="KRN00_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1827988.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            20238..20447
                     /locus_tag="KRN00_002124"
     CDS             20238..20447
                     /locus_tag="KRN00_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBH1827989.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            20467..21861
                     /locus_tag="KRN00_002125"
     CDS             20467..21861
                     /locus_tag="KRN00_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBH1827990.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSRNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            22101..22853
                     /locus_tag="KRN00_002126"
     CDS             22101..22853
                     /locus_tag="KRN00_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1827991.1"
                     /translation="MDEKRQKKEMDLEVNSFVPLYQQLYDNIKKQIASGIYKPGDKLP
                     SEGDLCKEFNISRITVRNALNELVKEDILCKKRGKGTYVTIPERIEATCAGNSFTNSC
                     HRINAKPSTKIISVLIKKADKQVAEALSIELEEKVICIKRLRLIDEVPVIFEVDYFRI
                     DYMFLLKEELEDKSLMEVISNNISTLPKRVENIFEVKHSNKEYSDHLKCASNMPLLKV
                     RQSVYTENNDVLYYNEQFIRSDKYKYAVSAEI"
     gene            22879..23292
                     /locus_tag="KRN00_002127"
     CDS             22879..23292
                     /locus_tag="KRN00_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1827992.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            23296..24039
                     /locus_tag="KRN00_002128"
     CDS             23296..24039
                     /locus_tag="KRN00_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBH1827993.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            24039..24509
                     /locus_tag="KRN00_002129"
     CDS             24039..24509
                     /locus_tag="KRN00_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1827994.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            24526..25284
                     /locus_tag="KRN00_002130"
     CDS             24526..25284
                     /locus_tag="KRN00_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1827995.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            25268..26110
                     /locus_tag="KRN00_002131"
     CDS             25268..26110
                     /locus_tag="KRN00_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1827996.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(26270..27175)
                     /locus_tag="KRN00_002132"
     CDS             complement(26270..27175)
                     /locus_tag="KRN00_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1827997.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
BASE COUNT        10767 a         3018 c         4971 g         8658 t
ORIGIN      
        1 aatagcacaa aatataagga gactaaaaat gaagaagttt ataaaagttt cattttttat
       61 tttggggatt tttacactat tcatagctat aaataaatta gtatatagag atatggtaag
      121 tgtcaaagat tatgaaataa atcatttaga ggaaattgtt tttgattttg atagcaggag
      181 aagtagagat gttggtacta ttgtaagatt taaaataagc aataatagta aatatagtta
      241 taaattaaac agtgctaaaa tgaagtttga aaattgtgtg gaaaataaaa agggaatgaa
      301 taagtgttct gcatatgtaa atgtagattt atttaatgaa aaaaattcta taactgaaag
      361 aactctgaaa tatggaataa aaccaaataa tcaaggttat gttgattttg taattccaaa
      421 aggactaaat tttgattata ggtactttaa tgaatctggt atgagtgtag agtataaagg
      481 agaatatatt gtcaatattc caatggcaaa aggactttat ctagtagttg gaaaaaataa
      541 tgatacatgg aatgctaata ttatggaata atttgaaaaa taaatcaatt atagatataa
      601 ttaagaataa tatgaaattt ataaaagttc agactaggag gggtatttaa tgtcaataag
      661 taatgtaaga gagtatttta aacaatttgg caaggaagac agtatattag aatttgaaca
      721 atctagtgct actgtggaac ttgcagctga agcagctggg gttattccag caagaatagc
      781 taagacactc tcatttaaaa taggagatga tgcaatttta attgtgacag ctggtgatgc
      841 taagattgat aataagaagt ataaggctga atttaattgt aaggctaaaa tgttgacacc
      901 agaagaagtc ttggagttta ctggacatgc tattggtgga gtctgtccat ttggtttaaa
      961 aaattctata aaagtctatt tagatgattc aatgaaaaga tttgatacag tatttcctgc
     1021 atgtggcagt agtaactctg caatagaact tacatgtgaa gaaatggaga agttttctaa
     1081 gtgtgaaaaa tgggtagatg tttgtaagaa ttggtaaaaa aatatagtaa actatagtag
     1141 gaattagtaa aaaactacct ctgtatacaa tctatacaga ggtagttttt ttgtgtaaat
     1201 atttataaat ctaagaggaa aatctaattt aaactaataa tccaaaataa agttaaaaaa
     1261 ttctgatttt ttttcgaaac aataaaaaaa tgacaaaaaa gtggaaaaaa tgtaataaat
     1321 attgttaaaa aaataattag aaattattga aaaattatcc tttgagtgat actattatag
     1381 atgtaagata tttaaaaata aaaaatagtc agataaaaat atgattattt agctctatta
     1441 aaataatttt tatacgataa aaatcttctg tacatggcta aaaaacagat gtacagacaa
     1501 tatttaatgt ttaatatacc ctaatataaa tatcgtaaac aaattatttt atctctaacc
     1561 agtgtgaaag aaatcttatt ctaacttgaa atttcacaaa attccaaaaa gcgagatttt
     1621 ttttaagtat agttgatttt aaattaacaa tttatgatta aattaatgtc ataattggtt
     1681 agtataatca catataaata tagagcgtag tttgattaag gttataaatt tctcgacgta
     1741 tattcaaata ccttattata gatgttgccg agattttaat taataaatga aaataaaata
     1801 tttataaaat actgaggagg ctattatgga tttaaattct aaaaaatatc agatgcttaa
     1861 agagctatat gtaagcttcg ctgaaaatga agttaaacct ttagcaacag aacttgatga
     1921 agaagaaaga tttccttatg aaacagtgga aaaaatggca aaagcaggaa tgatgggtat
     1981 accatatcca aaagaatatg gtggagaagg tggagacact gtaggatata taatggcagt
     2041 tgaagaattg tctagagttt gtggtactac aggagttata ttatcagctc atacatctct
     2101 tggctcatgg cctatatatc aatatggtaa tgaagaacaa aaacaaaaat tcttaagacc
     2161 actagcaagt ggagaaaaat taggagcatt tggtcttact gagcctaatg ctggtacaga
     2221 tgcgtctggc caacaaacaa ctgctgtttt agacggggat gaatacatac ttaatggctc
     2281 aaaaatattt ataacaaacg caatagctgg tgacatatat gtagtaatgg caatgactga
     2341 taaatctaag gggaacaaag gaatatcagc atttatagtt gaaaaaggaa ctcctgggtt
     2401 tagctttgga gttaaagaaa agaaaatggg tataagaggt tcagctacga gtgaattaat
     2461 atttgaggat tgcagaatac ctaaagaaaa tttacttgga aaagaaggtc aaggatttaa
     2521 gatagcaatg tctactcttg atggtggtag aattggtata gctgcacaag ctttaggttt
     2581 agcacaaggt gctcttgatg aaactgttaa atatgtaaaa gaaagagtac aatttggtag
     2641 accattatca aaattccaaa atacacaatt ccaattagct gatatggaag ttaaggtaca
     2701 agcggctaga caccttgtat atcaagcagc tataaataaa gacttaggaa aaccttatgg
     2761 agtagaagca gcaatggcaa aattatttgc agctgaaaca gctatggaag ttactacaaa
     2821 agctgtacaa cttcatggag gatatggata cactcgtgac tatccagtag aaagaatgat
     2881 gagagatgct aagataactg aaatatatga aggaactagt gaagttcaaa gaatggttat
     2941 ttcaggaaaa ttattaaaat agataaatat taaaatatac acaataggtc gatattaaaa
     3001 tagatatgga ggaaggattt atgaatatag tcgtttgtat aaaacaagtt ccagatacaa
     3061 cagaagttaa actagatcct aatacaggta ctttaattag agatggagta ccaagtataa
     3121 taaaccctga tgataaagca ggtttagaag aagctataaa attaaaagaa gaaatgggtg
     3181 ctcatgtaac tgttataaca atgggacctc ctcaagcaga tatggcttta aaagaagctt
     3241 tagcaatggg tgcagataga ggtatattat taacagatag agcatttgca ggtgctgata
     3301 cttgggcaac ttcatcagca ttagcaggag cattaaaaaa tatagatttt gatattataa
     3361 tagctggaag acaggcgata gatggagata ctgcacaagt tggacctcaa atagctgaac
     3421 atttaaatct tccatcaata acatatgctg aagaaataaa aactgaaggt gaatatgtat
     3481 tagtaaaaag acaatttgaa gattgttgcc atgacttaaa agttaaaatg ccatgcctta
     3541 taacaactct taaagatatg aacacaccaa gatacatgaa agttggaaga atatatgatg
     3601 ctttcgaaaa tgatgtggta gaaacatgga ctgtaaaaga tatagaagtt gacccttcta
     3661 atttaggtct taaaggttct ccaactagtg tatttaaatc atttacaaaa tcagttaaac
     3721 cagctggtac aatatacaat gaagatgcga aaacatcagc tggaattatc atagataaat
     3781 taaaagagaa gtatatcata taatttaagg ggggataaag aatgggtaac gttttagtag
     3841 taatagaaca aagagaaaat gtaattcaaa ctgtttcttt agaattacta ggaaaggcta
     3901 cagaaatagc aaaagattat gatacaaaag tttctgcatt acttttaggt agtaaggtag
     3961 aaggtttaat agatacatta gcacactatg gtgcagatga ggtaatagta gtagatgatg
     4021 aagctttagc agtgtataca actgaaccat atacaaaagc agcttatgaa gcaataaaag
     4081 cagctgaccc tatagttgta ttatttggtg caacttcaat aggtagagat ttagcgccta
     4141 gagtttctgc tagaatacat acaggtctta ctgctgactg tacaggtctt gcagtagctg
     4201 aagatacaaa attattatta atgacaagac ctgcatttgg tggaaatata atggcaacaa
     4261 tagtttgtaa agatttcaga cctcaaatgt ctacagttag accaggggtt atgaagaaaa
     4321 atgaacctga tgaaactaaa gaagctgtaa ttaaccgttt caaggtagaa tttaatgatg
     4381 ctgataaatt agttcaagtt gtacaagtaa taaaagaagc taaaaaacaa gttaaaatag
     4441 aagatgctaa gatattagtt tctgctggac gtggaatggg tggaaaagaa aacttagaca
     4501 tactttatga attagctgaa attataggtg gagaagtttc tggttctcgt gccactatag
     4561 atgcaggttg gttagataaa gcaagacaag ttggtcaaac tggtaaaact gtaagaccag
     4621 acctttatat agcatgtggt atatctggag caatacaaca tatagctggt atggaagatg
     4681 ctgagtttat agttgctata aataaaaatc cagaagctcc aatatttaaa tatgctgatg
     4741 ttggtatagt tggagatgtt cataaagtgc ttccagaact tatcagtcag ttaagtgttg
     4801 caaaagaaaa aggtgaagtt ttagctaact aatttcttgg ggagggtatt atgagtacaa
     4861 gtgatgttaa agtttatgag aatgtagctg ttgaagtaga tggaaatata tgtacagtga
     4921 aaatgaatag acctaaagcc cttaatgcaa taaattcaaa gactttagaa gaactttatg
     4981 aagtatttat agatattaat aatgatgaaa ctattgatgt tgtaatattg acaggggaag
     5041 gaaaggcatt tgtagctgga gcagatattg catacatgaa agatttagat gctgtagctg
     5101 ctaaagattt tagtatctta ggagcaaaag cttttggaga aatagaaaat agtaaaaaag
     5161 tagtgatagc tgctgtaaac ggatttgctt taggtggagg atgtgaactt gcaatggcat
     5221 gtgatataag aattgcatct gctaaagcta aatttggtca gccagaagta actcttggaa
     5281 taactccagg atatggagga actcaaagac ttacaagatt ggttggaatg gcaaaagcaa
     5341 aagaattaat ctttacaggt caagttataa aagctgatga agctgaaaaa atagggctag
     5401 taaatagagt cgttgagcca gacattttaa tagaagaagt tgagaaatta gctaagataa
     5461 tagctaaaaa tgctcagctt gcagttagat actctaaaga agcaatacaa cttggtgctc
     5521 aaactgatat aaatactgga atagatatag aatctaattt atttggtctt tgtttttcaa
     5581 ctaaagacca aaaagaagga atgtcagctt tcgttgaaaa gagagaagct aactttataa
     5641 aagggtaaaa atctaattaa aaatatattt gctgttaact agattaaata gtattttaat
     5701 ctagttaaca gaatataaat actaaaataa caggaggtta taactatgaa attagctgta
     5761 ataggtagtg gaactatggg aagtggtatt gtacaaactt ttgcaagttg tggacatgat
     5821 gtatgtttaa agagtagaac tcaaggtgct atagataaat gtttagcttt attagataaa
     5881 aatttaacta agttagttac taagggaaaa atggatgaag ctacaaaagc agaaatatta
     5941 agtcatgtta gttcaactac taactatgaa gatttaaaag atatggattt aataatagaa
     6001 gcatctgtag aagacatgaa tataaagaaa gatgttttca agttactaga tgaattatgt
     6061 aaagaagata ctatcttggc aacaaatact tcatcattat ctataacaga aatagcttct
     6121 tctactaaga gaccagataa agttatagga atgcatttct ttaatccagt tcctatgatg
     6181 aaattagttg aagttataag tggtcagtta acatcaaaag ttacttttga tacagtattt
     6241 gaattatcta agagtatcaa taaagtacca gtagatgtat ctgaatctcc tggatttgta
     6301 gtaaatagaa tacttatacc tatgataaat gaagctgttg gtatatatgc agatggtgtt
     6361 gcaagtaaag aagaaataga tgaagctatg aaattaggag caaaccatcc aatgggacca
     6421 ctagcattag gtgatttaat cggattagat gttgttttag ctataatgaa cgttttatat
     6481 actgaatttg gagatactaa atatagacct catccacttt tagctaaaat ggttagagct
     6541 aatcaattag gaagaaaaac taagatagga ttctatgatt ataataaata agaatttggg
     6601 aattaaaagt ttaaataaaa ttgtttaaaa aacaatttcg gatatatgaa aaatctaatt
     6661 taatgggggt aatgaatatg agagaagtag taattgccag tgcagctaga acagcagtag
     6721 gaagttttgg aggagcattt aaatcagttt cagcggtaga gttaggggta acagcagcta
     6781 aagaagctat aaaaagagct aacataactc cagatatgat agatgaatct cttttagggg
     6841 gagtacttac agcaggtctt ggacaaaata tagcaagaca aatagcatta ggagcaggaa
     6901 taccagtaga aaaaccagct atgactataa atatagtttg tggttctgga ttaagatctg
     6961 tttcaatggc atctcaactt atagcattag gtgatgctga tataatgtta gttggtggag
     7021 ctgaaaacat gagtatgtct ccttatttag taccaagtgc gagatatggt gcaagaatgg
     7081 gtgatgctgc ttttgttgat tcaatgataa aagatggatt atcagacata tttaataact
     7141 atcacatggg tattactgct gaaaacatag cagagcaatg gaatataact agagaagaac
     7201 aagatgaatt agctcttgca agtcaaaata aagctgaaaa agctcaagct gaaggaaaat
     7261 ttgatgaaga aatagttcct gttgttataa aaggaagaaa aggtgacact gtagtagata
     7321 aagatgaata tattaagcct ggcactacaa tggagaaact tgctaagtta agacctgcat
     7381 ttaaaaaaga tggaacagtt actgctggta atgcatcagg aataaatgat ggtgctgcta
     7441 tgctagtagt aatggctaaa gaaaaagctg aagaactagg aatagagcct cttgcaacta
     7501 tagtttctta tggaacagct ggtgttgacc ctaaaataat gggatatgga ccagttccag
     7561 caactaaaaa agctttagaa gctgctaata tgactattga agatatagat ttagttgaag
     7621 ctaatgaggc atttgctgcc caatctgtag ctgtaataag agacttaaat atagatatga
     7681 ataaagttaa tgttaatggt ggagcaatag ctataggaca tccaatagga tgctcaggag
     7741 caagaatact tactacactt ttatatgaaa tgaagagaag agatgctaaa actggtcttg
     7801 ctacactttg tataggtgga ggaatgggaa ctactttaat agttaagaga tagttttaga
     7861 ttataatatt tacaaattaa atatttaatt atgaatttaa cctgtaagaa taactatttg
     7921 ttattcttac aggtttttat agttaaaaat aattattatc tattaaacaa aaatagtgta
     7981 aaatatataa tatcatgatt ttgaagatat aaaaagtagg aagatataaa agaaagtagg
     8041 taaaagtttg tttaaaaaag agaatcaaag atataatctt atatcgtata caaatgaaga
     8101 agaaatgact ttaaaagaag ttttattggc caagctaaat ttctcagtta ggtcattatc
     8161 aaaaatgaag agggaaaaga gtgttttagt aaatggagta tataaaaaac cgagtttaaa
     8221 ggtgtatagt ggtgatttaa tagaagtaaa aatatacgag gaaaaagcaa attttgaacc
     8281 tcaagattta aatttacaga taatttatga tgattttgat ataattatgg tgaataaacc
     8341 tccgtttatg gtagttcacc caacaaaaag ccactatgat aaaacaatag caaatggtat
     8401 tagttactat atagataatc aaaaagaaaa cgtaaaaata agatttgtaa ataggttaga
     8461 tatgaatact tcagggttag ttatagtagc aaaaaatgct tatgcacatc atactttgtc
     8521 tacagcaatg agtgaaaata aagttgaaaa aaagtatata acagtagttg atggaattat
     8581 aaaagaaaat gagggaacta tagatgagcc aatttataga cctacagaag attcaataaa
     8641 gaggataata gatgaaagag gacagtcatc tgttactcac tataaagtaa tagaaagact
     8701 agaaaatgca actgtattag aagtaagctt agaaactggt agaacacatc aaataagagt
     8761 acatatggct catataggtc atggaataat aggtgatgag ttgtatggtt atgtagatga
     8821 agagctaata aataggcaag cacttcatgc atataagtta gagtttgaac aaccaagaac
     8881 aaaagaaaaa ttgaaattta aagcagatat accagaggat atgaaagagt taatatcgaa
     8941 attaagataa tggggtgata tatatgataa tacataaatt tataatacat gttttggaca
     9001 aaaatagtga tgttccaata ttaaatgact ttgaaggcaa agttaatcaa gaagtagatg
     9061 gttttttcca gaaagctata aaaagaattg caaaagatga ggatttaaga aaaggtgttt
     9121 ttaaagatta taatgacaat ttaattaaaa actgttgtga acaaataata tatgatgaaa
     9181 gtactttttt gaaaaattct aaagaaattg catcttactt gtttgatgtt atgaaaatta
     9241 atgctgcact agaatcttgt gatttggcaa tttgcttata cactattaaa gatgaaaaga
     9301 gtgtagcaat actgaaatta gattataaaa agttgtacac tcattcaatt gaatttgtgg
     9361 atgataaatt taatattcaa atggtttcaa atgaaattgg tatcccagag actttaagac
     9421 aaaagcaagg agctttgatt agtctaagtg gtataaatga tgagtttcat ctaaggcttt
     9481 tagataagga tgctgaaaaa gaagggtcag aatctaagtt tgtaacagaa tttttaaatg
     9541 ctaaaaaaat agatgatgat aagtacaaga ccaaggtatt taaaaataca gctgaaaatt
     9601 ggataaccaa tgctcttagt aatgatataa agcaagctga agatgtaaga agtatattaa
     9661 attatacact gaaggaaaaa catgaagttg atataaatga ctttgttgat aattcaatta
     9721 aagatgatga gttaaaggat agctttaaag agcatatgga agaaaaaggt cttgatgaaa
     9781 gttttagtat agataaaaaa tgggttgaga aaaagcttaa aaaaagaagt ataaaaacgg
     9841 ataatggttt tgacataaaa gggaatctaa ctgattttga agacccaatg aagtatactg
     9901 taaaacaaaa tcaagatgga actatagata taataataaa gaatgttacg ttttatgaag
     9961 aaaagtaatt tatatactta gtatataaat taaatataag agcgtgtatt ttatatattg
    10021 taaataaatg taatctagtc tgtgcgaact ctaatataat ttattatgta gaagtttaca
    10081 cagactattt atatttgtag acaaaacgat actatttgtt ttcttcgata tatttacata
    10141 tatcaccaat acatttaaag ttctcagctt cctcgtctgg tatttctatt ccaaattcat
    10201 cttcaagggc cattataatt tcaacagcat ctaatgaatc agcttctaag tcgtccatta
    10261 aagatgcttc catagttatc tcatctaaat tgtctacccc taattgttct gctattattt
    10321 cttttatttt ctcaaacatt ttaagcctcc taaagcagtt ttaattaatt ttaatgttag
    10381 tttaatataa tatcaagaat ttttcaatat ggaatctata aaaaataata aaattttata
    10441 aatgtagtaa taaagtatta tttgatgaat aaactttatt gataacaaat ataacttagg
    10501 aggaaatgct atgaaatatg taggactatt actaacttca gtaggaatgt ttttacttat
    10561 agcagtaaat ttttattata attcaataac tttagatatg caacgtatag aggattatgt
    10621 aatggagacc aatttaatcc ttgaagatgt agctgaaaag gagagttatg tatctaatga
    10681 aaaagaagac tacatatcaa ggttaatgca tgtaaagaaa ggaatagaaa attcaaaaac
    10741 atccttcttg atagaaagat ataaggagta caaaataaaa tcaatagaaa gtttaatcta
    10801 tactatatca gaggagaaaa aagattatct ggatgaagtt gatagataca ataaacttgg
    10861 tgaaaaagaa ataaataaac taatcaataa aaacttttta gaagtaactt atctgtctat
    10921 tactacatat atttaattaa agagacaaaa cttagtctct taatgattca aggaggatta
    10981 gttatgacaa aattagaaga caatatggaa cgtttctttg gaggatgcga aggatttttt
    11041 gggaataaaa tgttgataat aatagttata gtattcttac tattatgcac agacatttta
    11101 gaagacttat tatgcgatga caatatatgg atatgggtta tattaatagt gttgttacta
    11161 tttaacttcg atgatggttg ttgttgctaa aaaatattga ttattaaata ggtaaaacca
    11221 gtaacttata caagttatgg ttttaccttt tttagttcaa attaaaaaat ttaaaaaaat
    11281 agtaaaaata cattagcaaa atggaaacca aatgcatagt atatgttagg agcgaaaagc
    11341 tcaacaaaat atcaacagga ggtaacgtat aatgttagat agattctttg gagaagaagg
    11401 atgttttggt ggaggaggat ggtggataat agtactattc ttcctattct tagcttttgg
    11461 agatagctgg gcagaatttg acataatggc atggatacca ttcctaatag ttttattaat
    11521 actttgctgc tgtggtggat gcttagaata agaacacagt tattaaaaaa aggagggctt
    11581 tgttatgtta gatagatttt ttggagaaga aggatgcttt ggtggaggag gatggtggat
    11641 aatagtacta ttcttcctat tcttagcttt tgaagattgc tggagagaca ttgacataat
    11701 gtcatggata cctttcttaa tattattgct aataacttgt tcatgtggtg gattctttga
    11761 tggtgaagta ggttgcggct gctaatactt aaatcattag aataaaaaaa tgctggtatt
    11821 ttataccagc atttttttat tttatttttt aatatgattt aaattaagaa tgaatattat
    11881 taaatttgtt gaatataggg tataatataa aatataatgt atttaaatgt acttgctttt
    11941 atggtaaaat aaaaacttat ataaatgtag ttaaaatagg aaccttcaaa aatttggttc
    12001 agttttagat aaatttagta aaataaggag gatgaagatg aaaggcaata taacgataaa
    12061 agatgttgct aaacaagcag gagtgtcaat atctactgta tctagagtta taaatgattc
    12121 aaaacctgta actgatgaag tcaaacaaaa agttttagag gttataaaag agactggata
    12181 tataccaaat ccacttgcta gaagcttagt aacaaagaag agtcaattaa taggggtaat
    12241 agttccagaa gtttcagatt cttttgttaa tgaggtgtta aatgggatag aagaggttgc
    12301 taaaatgtat gactatgata ttcttttagc gaatacatac tctgataagg aacaagaact
    12361 taagagtata aatctattga gagcaaaaca agtggaaggt atagttatga tttcatggat
    12421 agttgaacaa gaacatatca actatataca aaattgtgga ataccagcga catatataag
    12481 taaaactgct agaaattatg atatatatac agtaagtact agcaacgaag aagctacttt
    12541 tgatatgaca gagcatctta taaagaaagg tcatgaaaag atagctttta taatgacgag
    12601 taaagatgat actgttttag aaatggaaag acttgctggt tatgagaaag cactttcaaa
    12661 taacaatata gaattagaca agagtttgat taagtatggt ggaactgatt atgagagtgg
    12721 atacaatagt atgaaagaac tattagatga tggaataata cctcatgcgg cttttgtaac
    12781 aggtgatgag gctgccatag gtgctataaa tgctatatgt gatgctggat ataaggttcc
    12841 agaagacata tctgttgcag gatttaatga tgttaagata gctagaatgt atagacctaa
    12901 acttactaca gtatatcaac ctctatacga tatgggagca gtagcaataa gaatggttat
    12961 aaaattaata aataaggaat taattgagaa taagaaaata gaattacctt atagaattgt
    13021 tgatagagaa agtgttacag aaagaaaaaa ataaaactat taaaatcaat caggtagtgc
    13081 ctaaggcact acctgatttt ttatgtcaat aatatcaaat ttaataatag attaactaaa
    13141 aataattatc taattactta aatagtttat ttttatctat tcatgagggt tagacttttt
    13201 agttttctta aataaacttt tagatttttt ttgttgacta cctggtgtat tttttggtgc
    13261 aggtgaattt gacttacctt tagtaggttt agccttctta gttttagctg gtttagtatc
    13321 tctttggttt tctgcatctg agattttttc cattatatta tccagttttt tgcgttgatt
    13381 ttcatctaaa aatgctttga attttgatac tacttcatct ctgccatcta ggttcttacc
    13441 tatttttata agttcctcca taagttcatt ttctgatttt cctttgtaac tatcagccat
    13501 cttttctatt ttatccttgt caatattttt ttgtttagcc attttttcta atgactctgt
    13561 atctaatttt ttcataaaaa aacccctttc tataaatata tattgaatta tattcatact
    13621 atttatatat agaaataata ttgaagtggt gaattgtgag tgatatataa tataaataaa
    13681 aattcttata gataatatat atgcactgag ctttaaaaat ggaacattaa aatatgaaaa
    13741 acatacttta atatagggca attatataat ataaggggga attgtcttga ataacttact
    13801 atttttgatt ggagtgattg cattgagtaa tggtaatatc tctatatttg atgataaaaa
    13861 taaatcaaaa ggaaataata gagttagaaa aaacaaaaaa aatgcaaatg ataaactttc
    13921 acagtctaca catggcaatt taaggtttga tgcaaatgat ataaaaagag gtttaaggct
    13981 catggattta agtgaagaag atttagaaat gggaatggaa ataataacaa gaactaaaaa
    14041 atacatgtca agagatgaaa gaaaaatact aataaaaata gaaagtgttt tagatttagt
    14101 tagaggaata aaaaaattaa ataatataga tatggtagat acagaagatg aaacggattt
    14161 tttcagaaaa atggatagtg atgataaaaa gaatatgatg ataaaggaaa ttatagatgt
    14221 attcccagaa aaaagaaaaa attcagttga aaaagctata ggaatgaaaa agaagataga
    14281 tttatttgca gaattatttt taccagatga ctttggtgaa ggtggattta gtttgagctc
    14341 tttggcaaat ataaacaatc ttggtagtat gaataatctc aaattgttag gaagtctttt
    14401 aagaggtgat gatagtaata atgatgatga agacaataat gatgagttaa attatgaaga
    14461 cgaagaatta gattgtgaag acaaagaatt ggatgatgat gagttaacag atgaaggtga
    14521 aatggaggat aatgaagatg aattagtaga agataagaac aaaggctatg aaaatataga
    14581 aaatgatgaa gatatagtat atgatgagga actatacaac attaatgagc aagaatccga
    14641 atacaattat aatgaaaaaa atactaaaac tagagctaag aaaaaacgat aattaactaa
    14701 atacataaag aaaaaaggaa gaaaaagtaa tgatagaata agattatctc aattactata
    14761 taaaaccact ttaaaaaatt caaaatttat tatataataa taatatgaaa tcctgaaaca
    14821 tacgataagg cttttttaaa ttcaacctac aaatgaaata cgggagaccg tgtctggtaa
    14881 attataacat gcctagttag tttggacgtt aaaggttact ggcaagtcac ccacctggga
    14941 gtgcctaggg tgtgaattta cttagccacc ggtgtttcgg gacaaaaaaa gtgctactat
    15001 ttcaaatagt agtacttttt ttattaatat gcatttttct actaaatacg cctaattatt
    15061 gataaattca aaaagcaagt aacaattaag attataaaag catagtatta attaggcttc
    15121 aaaaagccaa agacttaata agaatcgctt acagggaggg caatgaaaaa tgcaagatta
    15181 taaaaaaaat aaaagaagaa tgatgaatca gccaatgtct acaatgaatg aagaagaagt
    15241 gtatacagat gaaataaatt cagaagacat gagaggtttt aaaaaatcac accatcataa
    15301 tggatgtaat actgataata agtgtgagtg ccatgatgat tgcaatccat gcaacccatg
    15361 taatccatgt aaacctaacc catgcaatcc atgcaaacct aatccatgtg atgacaattg
    15421 tggatgccat gacaattgta aatgtgattg tgaaccatgt gaaatggatt cagatgaatg
    15481 ttttgaaaac aaatgtggac cagaatgctg taatcctata tctccaagaa acttctctgt
    15541 atcaaatgca gtgccatttg caatagaggc taatagaata tttgatacta tgcaattcca
    15601 aacatttaca gatgcaacag gaccaaatgg agagccatta acttttgaaa cagaagtagt
    15661 agaagtattt ggttcagttc caagtgcagg tcaagcaagt gtaactatag aaaaaatatg
    15721 cttaagtaat gatggaatag ttatagacac aggaatgaca actttagaag atttcgattt
    15781 agacccatta ggagatatag taggaagaaa ctgtgaaaca acttttgaat ttgcagtttg
    15841 tggagaaaga aacgctgagt gctgtagaca aggaaaaggc aaatcagtag cttataaaca
    15901 aagaggatta actgtagcag ttcgtaattt agtactagag ctaagaggta gatgtggatg
    15961 tacagagttc gttgcattag ctttcccagc agttagagca ggaggtggat gtaagagaag
    16021 agttgattat gtagaattta cttttaacac actttcagca ccaatatgct tgccagctga
    16081 tggaagagct gttactttaa gacaagaata tcaaactaac ttaactgtag attgtatagg
    16141 aaaatctata ttaaaattag aatgcaacga atgttgtgaa cctttctatg aattaattat
    16201 accaaatgat atagatttag tactttgctt acaagaaaca gttagcacat taataagtga
    16261 acaaatagta gttttagcat caccaaatcc aatccaacca agacttgttg atactttctc
    16321 taaagtatgt gatttttcgc aatgtggacc taatcatgga agtggaaagc caagttgcca
    16381 cagatagata ggtagatata tagacagttt aaattataaa taaaaatcat ctaaggaagg
    16441 ctaccaaagt gtataattta cattggtagc cttcacgttt ttataactag cgtatagatt
    16501 ttagtgattt aaaaagcact atagtatgta atagacaagt aaagattgat actatcgtca
    16561 ttgtgtatat gtatgcataa atattaagtt ctggaattgg aagaaataca tataaagcta
    16621 ttagttgaat taacatgcca gtaatagtat ttatacttga agctaattct tttcttattg
    16681 aatgtaaaat gccagataga gtttgattta gggacataaa tagtggaact aaaaacatag
    16741 cttttagata ttctcctgca agtgtatttt taaatactaa tatacataaa tcttttccaa
    16801 agaaataaaa aaatattgat gatagtatgc ctacaaataa agtaagaagt atggagtatt
    16861 tgattttttt aattacactc ttacgctttc ttagagccat ttcttgtgaa atagttggta
    16921 ttaaatttac aataagcgct gaaccaacag taaaaggtaa aaatataaaa ggcattacca
    16981 tcccactgac aataccatac atacttaaag attgttgata agtcattcct gataatgcta
    17041 atcttgatgg tatcatcata gaacttatag attgcaaaag tatgtttgac attctattac
    17101 aagttatggg aatagacatt tttaatgttt ccatagaaga attataaaaa tcttttatgc
    17161 ttataatata cctattgtca aatgatgaat ctcgccataa gcaaataagc ataaatataa
    17221 tattactcaa ctcaccaatt gatataccta atagagctat ataacaattc atagatttat
    17281 tatttatgta cataacaagt aaaaaaacaa ataatatttt accaatttgt tcaatgattt
    17341 gtccaatagc agggattttt acattcttta tgccatagta atatcctctt agtacgtttg
    17401 aaagagttat tataactata gcaggacaaa cagctagtat aaatagattt aatttagcat
    17461 cttttaaaaa tttaagtgat aaaaaagaac tattgaaaga tgcaactata gatataatta
    17521 gtgctacgaa aaatgatata tataaagttg atataaataa agcattagta ttgtgtctat
    17581 cgtttaaagc ttttctcttt gcaactagac aactaagtgc agtaggtata cctgttgttg
    17641 taacagctaa gcaaatcatc aaaaagttaa aaatcatatg atagatacct aaacctgttt
    17701 cacctagtgc tcttgataag aatattttat ataaaaaacc aaatattctt acaataaaat
    17761 tggatataaa taaaataact gttgatagta ctaaataagg tactttcaaa aaaatcacct
    17821 ccttatcttt taaatatatt cacaaggagg tgtaaaaatt tataatttta taaattctgg
    17881 tttcaattta ttaaatttag atacatattt aaatcccata ttttttagta atgaatatat
    17941 gtagtcaaac tcacatgcaa cttgacttat atgatgtgaa tctgaacctg tggttatgat
    18001 ttcccctccc aagtctttat acatttgaag tatatactta gatggggtta ggtctggaag
    18061 attatatcta taacaagagg tatttatctc gatacctttg ccatcataaa tagcttgttt
    18121 aagagtttct tcaattatat cagaaaatag tctatcatct aaaatagtgt cataaggtgc
    18181 atacctttta atcaaatcta aatgacctaa gacagagtaa tctttataat tcttaacaat
    18241 attatataaa taaagatagt aattttcata aacttcatgt tgagttttat ctttaaaata
    18301 attaccaagg tataagtcca ttgtatctat agcatggata gaacatatta taaagtccaa
    18361 tggatattga tgtgcttcct ttttgtatgt atccattaat tgagtttgaa ctccaaattc
    18421 aattcctttt tttattgata ttttatcttt atatttgctt tgaagagtct ctaaactctt
    18481 aaaataatct tcgtagacaa ttgaaaaaga atcatcagca tatacatcat agtcaacatg
    18541 gtctgtgaaa caaatttcct ccaaaccgag ttcaatagat ttttttacca tttcttccat
    18601 tgtagatttt ccgtctgtag agaaacttga gtgcatgtga tagtcgtaaa acataaatat
    18661 ttcccctttt tataaaaatt ttggtattat atatacatac taaataatat caaatataca
    18721 taaaagcatc aataaaatat aaatacaatg agcggtgata aatttggaaa aatacagaat
    18781 agatttaaat gagaaaaaat caactaaata tatacagata tttaatcata taaaagaatt
    18841 gataataaat aaagagttag tagaacatga aaaattgcct ccaataagaa aactatcaaa
    18901 ttttttacaa gtaaataaca ctactatagt taaggtatac gagcttttag aaaatgaagg
    18961 atatgtatat aaaattatag ggagtggtac ttttgtatca agtttaaatt cttataaaag
    19021 cggtatagat aacaggaaaa ataagattat tgtgcaaaga gaagatttaa ttcattttga
    19081 caatgggaat ccatctaatg atatgtttcc tatcgattca tttaaaaatg ctgtaaatat
    19141 ggcattatct aaagatggta gttcaatatt tgaatatgat gaaggtcttg gctctgaaga
    19201 attaagagaa aaaatggtag agtatctaag tgatggaaat ataaaaacta ctaaggaaaa
    19261 tattcaaata atatcaggtg ctcaacaagg tatagatata gtttgtaaag gacttataag
    19321 ttattcagat gttgttttta tggaagaacc ttcttacaat ggagcaattg aagtgtttaa
    19381 aagtagaggt gcaaaaataa tatctatacc tatgttagat gatggaattg atataggtat
    19441 tttaaaatta aagttggaaa aaataaaacc aagacttata tacattatgc ctaattttca
    19501 aaatccaact ggaatatctt actcaacata taaaaaaaag aaattgatag aattggcaga
    19561 agaacatgat ttttatataa tagaagatga ttttataagt gattttgttt ttgaatcaaa
    19621 ggacaataga acaattagaa gttatgatga taaaaataga gtagtatata taaaaagctt
    19681 ttcaaaaata cttatgccag gtcttaggat aggaattgta gaaatgccaa atgagttgtt
    19741 aaaaaaagtt ttatgggcta aatattcatc agatatatca acaccaggtt taattcaaaa
    19801 atcaatgtat tactatatga ataattttga ttggaagaat tatttgagtc atatagagaa
    19861 gatatatact gataagtata aattggcaaa aaacttgatt aatgacaaat tgagtggtaa
    19921 attaaaagtt agaaaatctt gtggaggaat aaactttttt ttagaattac caagaggata
    19981 tacatctcaa gcatttacaa attttatgtt aaacaaagga gtgtcaatgc ttccaggaac
    20041 ttattttttt gacaatctag tggatgatag attctttagg ataaatatag ctcgtccaag
    20101 catggaagaa ctagaaaagg gaatatctat aataagtgat aatatagatg agtttttttg
    20161 tgaatataaa aacaagttag atataaaaag caataaatta ttttattaaa taaatagagg
    20221 ttttttagga ggaaaaaatg tttgacaaga agaaattaga taggattaat gaattagcaa
    20281 agaaaaataa agagggaatc ctttctgctg atgaaatcaa agaaagagaa attttaagga
    20341 aagaatattt agaaaacttt agagcccact ttagatcaag actagatagt gtcaaagtag
    20401 tttcaccaga agaatatgag caatacatga aaaacaataa aaattagaac ttagtaggag
    20461 gaaaatatga acttaaagta cgaatttaag aatgcttggg attttgaaag aaaagaaaat
    20521 actattgaac aaattatgca atattctcgc aattatatgg agtttttaag taagtcaaag
    20581 actgaaagac tttcagtaaa agaaattata aaattggcta aagaaaataa ctatatttca
    20641 atagatgaag ctatggaaaa aggaagcata agttgtggtg ataagattta tgtcataaat
    20701 aaagagaagg cagtagcact ttttgtaata ggtaaaaatt atatagaaaa aggtatgaag
    20761 attataggaa gtcatataga ttcgccaaga ttagatttaa aaccaaatcc actgtatcaa
    20821 gagagtaatc taggtttttt taagactcat tattatggtg gaataaaaaa ataccaatgg
    20881 acggctattc cacttgcttt acatggtata gttatattaa atgatggaac aaaagtggac
    20941 atatctattg gggaagaaga tagtgaccca gtattttgtg taactgattt attgattcat
    21001 ttggctggag accaaatgca aaagaaacta tcagaaggaa ttagtggaga agctttaaat
    21061 atattaattg ggaatatgcc tttagaagat gaagaaaaag aacctataac agcaaatata
    21121 ttaaagattt taaatgagaa atacaatata gttgaagaag atttattaag tgctgaaatt
    21181 gaagtagttc cagctggtaa ggctagagat ttagggcttg ataggtctat ggtgttggga
    21241 tatgggcatg atgatagggt atgttcatat gctgctgtaa aagctatact agaaactgaa
    21301 caaccagaat ttacttcagt tgcattatgt gtagataaag aagaaattgg ttctaaaggg
    21361 aatacaggta tgcactcaaa gttttttgaa aatactgtgg ctgaactgat tgctttagaa
    21421 ggagattatt gtgatattaa agtaagaaga gctttagcaa atagtaaggt attatcagct
    21481 gatgtttctg ctggatatga cccaaatttt ggagaagcat atgaaaagag aaattcggca
    21541 tatatgggaa atggagtagt tttaactaag tatacaggtt caagaggaaa gagtggatgt
    21601 aatgatgcta atgctgaatt tatgtcagaa gtaaagagga tttttaataa aggaaatgta
    21661 gtatggcaaa ctgctgaact tggaaaagta gaccaaggag gaggcggaac tatagcccat
    21721 atattggcaa atcaaggtgc agaggttata gactgtggtg ttggagtttt aaatatgcat
    21781 gcaccacatg agattgtctc taaagtagac atatatgaaa tgtataaggg atataaggca
    21841 ttttttaata taaatttata agtaaaaata taaatgtaat aagtgaataa aggctgttgt
    21901 ataaacaatt taatctgttg tacaacagtc ttatttttat gtaaaaatag caatttgtca
    21961 cactagagaa aataaaagaa aatactgtca aattaaaaat tatttaaaaa aaaattgaca
    22021 acgatttcat cttgttataa tatgtaataa agaacttgtt atataatgtt ataaaaatgt
    22081 tacataggga ggtgagcaaa atggatgaaa agagacaaaa aaaagaaatg gatttagaag
    22141 taaattcctt tgttccttta tatcaacaac tatatgacaa cataaaaaaa caaatagcat
    22201 ctggcatata taaaccagga gataaacttc catctgaagg agacttatgt aaagaattta
    22261 atataagtcg tataactgtg agaaatgcac ttaatgaact tgtaaaagaa gatatattat
    22321 gtaaaaaacg tggtaaaggg acttatgtaa caataccaga gagaatagaa gcaacatgtg
    22381 caggaaatag ttttactaat tcttgtcatc gtattaatgc aaaaccaagt accaaaataa
    22441 tctctgtttt aataaaaaaa gcagataagc aagtagctga agctttaagt attgaactag
    22501 aagagaaggt aatatgtatt aaaagactta gattaataga tgaagtacct gttatttttg
    22561 aagttgacta ttttagaata gattacatgt ttttattaaa agaagaatta gaagataaat
    22621 ctttaatgga ggttatatct aataatataa gcacattacc taaacgagta gaaaatatat
    22681 ttgaagtaaa acattcaaac aaagaatatt ctgaccatct taaatgtgca agtaatatgc
    22741 cactattgaa agtaagacaa tcggtgtaca cagaaaataa tgatgtctta tattacaatg
    22801 agcaatttat aagaagtgat aagtacaaat atgcagtatc agcagaaata taatctataa
    22861 tttagtagga ggatgagtat gaaaaagata atattagcat ctcatggaga cttttcaaaa
    22921 gggcttttaa atgcagtaaa aatgatagta ggagatttag cagattgtgt cagttcgtat
    22981 ggtttatacc ctggacaaag tgcttcagat tttgctttag aattagaaaa aacaatatca
    23041 gaagataaag aatgtgaata tataatttta tctgacttat atggagcaag tgtatgtaca
    23101 gcaatgttaa gattaactaa tctacataat gttaggttat tttctggaat gaatttgaat
    23161 atggtattag aacttcttac aaggttttct gatgaattaa cagttgaaga tatagaccaa
    23221 ttagtggaag aatctagaag aggaatacaa agcgtgacat tacaaattaa agaagaagaa
    23281 gaggtatttt agtttatgaa aaaaaaggga atattatcag tatttaaaag taaaaaacca
    23341 attatagcaa tgatacactt aaaaggagat actccagaag atatctttga aagagctaaa
    23401 aaagagatta caatctttga agaaaatggt gtagatggaa taatgttaga aaattactat
    23461 ggtaattatt atgatttaga aagaatactt gaatatgtat caaaagctaa tttatcaata
    23521 ccatatggag taaactgttt aaatgttgat actatgggat ttgaactggc aacaaaatat
    23581 aatgctagtt atatacaggt tgattctgta gtaggtcatg ttaaacctag agatgaagct
    23641 actttagaag agttttttaa attacaacgt tcaaaatgcc cagcgtattt aattggaggc
    23701 gtacgtttta aatatcagcc agtattatca gaaaatgatg ttgaagaaga tttaaaaata
    23761 ggaatgacaa gatgtgatgc tatagcagtt acagaaaatg ctacaggtca agaaacatca
    23821 atggaaaaaa tagaactgtt tcgtaaaaat ttaggagact tcccattggt tatagctgct
    23881 ggagttacat tagaaaatgc aaaaaaacag cttaaattag gagatatggc aataatagga
    23941 agttacttta aagataatta caaagatttt ggggatgtta gtgtagaaca cgtaaaaaca
    24001 ttcatggatg aaatcaaaaa aattagggag gaattataat gattaaatta gtaagagtag
    24061 accacagact tatacatgga caagtagcat ttacatggac aaagttttta agcacagact
    24121 gtatattgat agcaagtgat gacttattaa aagatgaatt gagaatggca ggacttaaaa
    24181 tggctaaacc atctaatgtt aagttagtaa tgaaaagcat agcagattct ataaaagcac
    24241 ttaactcagg tgttactgat aaatacaact tattgatact ttgtgaatct gtagaagatg
    24301 tttatagact tgctaaagag gtaaaagcta ttaaatctat aaaccttggt ggaacaaaat
    24361 cagatgataa tcgtgaaaat atatctaaag cagtgcatgt atcaaaagat gatataaaga
    24421 tgattaaaga gttagattca gaaggcgtaa atgtatttgt acaattagtt cctgatgatg
    24481 atgctacaaa tgtaatgaaa ttaatataat tttaggggga tgaaaatgga atttacacaa
    24541 gttattttga taactctaat tgcattcttt gcatatatgc atagttttgt aggttctaca
    24601 atgcataata gacctatagt tgttgcacca cttgttggtt tagcactagg taatcttcat
    24661 acaggtatag taataggttc aacattagaa ttagtattta tgggtgcatt tcctgttggg
    24721 gcaagtaatc ctcctgattt tgtgtctggt tctattattg ccacagcgtt tgtaatatta
    24781 acgggtcaag atgtatcagc agcagttgta cttgcagttc ctatagcaac tctagtattg
    24841 cttatagata acttcttaat gacagtagta cttacatggg gagctcatat tgctgaccgt
    24901 tatgcagaag aggggaatat tgaaggcgta gaacgtgtgc aattattatt tggtatagga
    24961 aataaattaa tattagcaat aatagtaggt ataggatttt cattaggtgt tccagtaata
    25021 gaaaaaatac tttcatttat accatcatat gtaactcatg gaatggatgt tgcagcaggc
    25081 gtgattccag caataggttt tgccatgtta gctagaatga tgcttaataa gaaaacagta
    25141 gcatttttat tattaggatt tatattggtt gcttacctaa acataacagt aacaggagtt
    25201 gcattgtttg gattagcaat agctttaata tatgttaact ttgtaggaga gaaggaggta
    25261 atagtagatg acaacgagtt ctaagaaatt agagacaatt tcaccagata gtaaaataac
    25321 gaggaaagac ttttggaaat gttttagaag gtcattgaca ttagattcat cttggaacta
    25381 cgaacgtatg caaaatatag catatgcata catgatggca ccaataatcc gtagattata
    25441 taaagatgat aaagaaaaga aatctaaggc tttaaaaaga catttagaat ttatgtcagt
    25501 tactcctcat ataagtactc ttttggtagg tatatctgga gctatggaag aagaaaatgc
    25561 aaagaataaa gaatttgatg ctaatagtat aaatgctgtt aaatcaagtt taatgggtcc
    25621 agtttctggg ataggagatt catttttctg gggaacatta aagcttatag cagctggggt
    25681 tggtatagct ttagcttctc agggtaacat aatgggaccg attttattcc ttttaataat
    25741 aaatgttcct cattttatta tacgctatat atgtctagat aaaggattta agtatggaac
    25801 tcaattcttt aaagatgtga gtggttcaag tatagtttca aaagttatgg aagcagcttc
    25861 aatgttaggg cttatggtaa ttggaggtat gactgcatct aatgtaatgt taaaacttag
    25921 tgttaatgta ggtagtggag aatgggcaga gcctattcaa acttacttag accaaataat
    25981 gccatgtatg cttccagcta tgatattcgg tattatgtat tggttattag gaaaaaaggt
    26041 aaagacaact acgatattaa tttcagttat gattatttgt atagtattgg ctgctattgg
    26101 agtagtataa ataaaaaaat cccaagttca tttgaacgag ggattttttg actaaattaa
    26161 ataaaaaaga aagatggttc ataataattt ataagcattt atgtgatagt tataattagc
    26221 ttattaatta gttataaact caaaattaag cactacttta ttaaagttat tatattataa
    26281 tttcgaaata ctcacataat ctgtttagaa atttatcttc taatggggaa aaagttttct
    26341 ttttagagta aatgaagaaa aactttctag taaaatcaac atcctttatt ttataacatt
    26401 ttattttacc tgcattgaga taatcaatag ctgaaatgta cgatataaag gatactccaa
    26461 gacctaatct aaccatttcc ttaatagcct catttgattc tacatgagcg attacattta
    26521 atttacttac tggaaagtta tttttactaa gtgtgtttag tattaagttt cttgtacctg
    26581 acccttcttt tctcataata aaatttagat aagccaattc tcctatatcg atacaattat
    26641 ttttattatc aattttaaaa tctgaaggag tgataagaac aagttcatca tctaataagt
    26701 ctaggtactc tatttgagga ttattgattt tagaaccaac taatccaaag cttattcgtt
    26761 catttaaaat ttctgatata gcatattgag aatcataatg gcttatggaa aattttacat
    26821 ctggataact catagaaaaa ctcttcataa aatcaggtaa aatataagtt tcaggtatgg
    26881 aactacacgc tatatctata ataccttcta tttttcctga atattctttt atatcataaa
    26941 ttgcacgttt gcaattattc aatatatata tagcatgttc gtaaagaatt tcaccagatt
    27001 ttgtgagtgt aataactttg ttgcttctat ttataagaac agtttctagc tctctctcta
    27061 aattctgtat gtgtgcgctt acagtaggtt gagttaaaaa aagttctctt gcagcctttg
    27121 aaaaactctg atgttttgca acagcaacaa atacttcaag ttgtttaaaa tccattattt
    27181 aatcctcctt aaattatcta aaactattat aacatatttg ataaattaat agtcaaaggt
    27241 gatttttaaa atagaaaacc tttaaatatt catggagttt ttgattgttt aggaataatt
    27301 tggtataatg ttgtaaggta cttacaataa aaatatcgta aattgaattt tcaaaattca
    27361 actttaaaat gttttttatt acagaaaaat tacaattagc ttcttaatct tatt
//
LOCUS       DAEQAF010000047        27147 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.048, whole genome shotgun sequence.
ACCESSION   DAEQAF010000047 DAEQAF010000000
VERSION     DAEQAF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27147
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.048"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(45..905)
                     /locus_tag="KRN00_002133"
     CDS             complement(45..905)
                     /locus_tag="KRN00_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBH1827998.1"
                     /translation="MAMKWRDYAADVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEIEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(1222..2550)
                     /locus_tag="KRN00_002134"
     CDS             complement(1222..2550)
                     /locus_tag="KRN00_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1827999.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(2698..3027)
                     /locus_tag="KRN00_002135"
     CDS             complement(2698..3027)
                     /locus_tag="KRN00_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1828000.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(3051..4340)
                     /locus_tag="KRN00_002136"
     CDS             complement(3051..4340)
                     /locus_tag="KRN00_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1828001.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(4356..4682)
                     /locus_tag="KRN00_002137"
     CDS             complement(4356..4682)
                     /locus_tag="KRN00_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1828002.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(4817..5446)
                     /locus_tag="KRN00_002138"
     CDS             complement(4817..5446)
                     /locus_tag="KRN00_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828003.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(5661..8318)
                     /locus_tag="KRN00_002139"
     CDS             complement(5661..8318)
                     /locus_tag="KRN00_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1828004.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(8677..9621)
                     /locus_tag="KRN00_002140"
     CDS             complement(8677..9621)
                     /locus_tag="KRN00_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828005.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(9614..10639)
                     /locus_tag="KRN00_002141"
     CDS             complement(9614..10639)
                     /locus_tag="KRN00_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828006.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKSEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIEVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(10714..12282)
                     /locus_tag="KRN00_002142"
     CDS             complement(10714..12282)
                     /locus_tag="KRN00_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1828007.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(12395..13306)
                     /locus_tag="KRN00_002143"
     CDS             complement(12395..13306)
                     /locus_tag="KRN00_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828008.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIKNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(13290..14276)
                     /locus_tag="KRN00_002144"
     CDS             complement(13290..14276)
                     /locus_tag="KRN00_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828009.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            14636..15037
                     /locus_tag="KRN00_002145"
     CDS             14636..15037
                     /locus_tag="KRN00_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1828010.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            15040..15438
                     /locus_tag="KRN00_002146"
     CDS             15040..15438
                     /locus_tag="KRN00_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBH1828011.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(15888..16112)
                     /locus_tag="KRN00_002147"
     CDS             complement(15888..16112)
                     /locus_tag="KRN00_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBH1828012.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(16147..17514)
                     /locus_tag="KRN00_002148"
     CDS             complement(16147..17514)
                     /locus_tag="KRN00_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1828013.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFVGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPI
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(17598..19133)
                     /locus_tag="KRN00_002149"
     CDS             complement(17598..19133)
                     /locus_tag="KRN00_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828014.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EVSLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVRNYIESIDIENRFCNLFKKKDREKLFYDYGVTYK
                     IDCDVILVNLFELIINNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     GSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTFKSMVTVSKNKKEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(19156..19590)
                     /locus_tag="KRN00_002150"
     CDS             complement(19156..19590)
                     /locus_tag="KRN00_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828015.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(19850..20761)
                     /locus_tag="KRN00_002151"
     CDS             complement(19850..20761)
                     /locus_tag="KRN00_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBH1828016.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            21057..21410
                     /locus_tag="KRN00_002152"
     CDS             21057..21410
                     /locus_tag="KRN00_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBH1828017.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIFLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(21624..22565)
                     /locus_tag="KRN00_002153"
     CDS             complement(21624..22565)
                     /locus_tag="KRN00_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBH1828018.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(22666..23901)
                     /locus_tag="KRN00_002154"
     CDS             complement(22666..23901)
                     /locus_tag="KRN00_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBH1828019.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSQSKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYISLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            complement(23945..24799)
                     /locus_tag="KRN00_002155"
     CDS             complement(23945..24799)
                     /locus_tag="KRN00_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828020.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(24927..26102)
                     /locus_tag="KRN00_002156"
     CDS             complement(24927..26102)
                     /locus_tag="KRN00_002156"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBH1828021.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(26201..27085)
                     /locus_tag="KRN00_002157"
     CDS             complement(26201..27085)
                     /locus_tag="KRN00_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH1828022.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
BASE COUNT         8642 a         4854 c         2791 g        10860 t
ORIGIN      
        1 tttgtattat ataataagta tttttaggat tctgttacat aatattattt aaatattctt
       61 ctatatttct cttcttcttc ttcagtaaac acattaaata caacttttaa atttttttca
      121 ggattttctt ttagccatag tctaactcta cttacagcaa gattagctgc ctcttttttt
      181 ggataaccaa atacacctgt agaaattcca caaaaaacaa tattttttat ttcatcaatt
      241 tcttttattg tatttaaaca tgatttataa caatgaagca gttgcttttc ttgctcttta
      301 cttggctgac caccagatac aataggtcca acagtatgta ctacaaattt tgcaggtaaa
      361 caataacctc tagttatctt agcatctcca gtatattcta aatgcccttg tttttttatt
      421 attttgtcac aatcttctct aagtctagga cctgcgcatg aatgtatttc attatccacg
      481 catagatgta atggttgtaa acaccctaat aacttgttat ttgcagcatt tactattgca
      541 tctgctctta aattcgttat attacctctc catatggcaa tcccttcctc tatttcttct
      601 atatcattta catctactaa ctctctttct tcacattcaa tcaacaataa attatgtaac
      661 atattaagta tctctggagc aatttctttt ggtggatata cattcaaaag tcctctaagt
      721 atatctctag gcttaatttc atcatttgat aaattgtata ttttagaagg aacttctttt
      781 gaaaaatatg caattaaagt gtttatattt tttcttcttt gttcgtcagt tagaggcttg
      841 atagttttat caaaatcctc aaataaattt acatcagcag cataatctct ccacttcata
      901 gccatctctc cattcttgta ttttagactt aaaaataatt atgtatttat gtacatattt
      961 atttatttct ataaacacct acataaatcc tgttaaaagt gtaaattttt tattatgcaa
     1021 cttctctggt tatttctatt gattgatagt aaattattgt acctaaattt aatccaacta
     1081 acaagtaact aaacctactt tcctaactgc aaaatacact atgtttgcca cttgtatctc
     1141 atttgtagat aaataaagtc cctacaaata cattaactag gctatgtact aaactgtagg
     1201 aactttaaaa atatattatt cttaattaag ttttggccaa taatttttat ttgcttctat
     1261 taaatcatct agtaattctt ttgcaactgt tgcactagga actgtcttag atagcataag
     1321 tgcttgccac aatttattat aagacttctc aatccaagca tcaactacta atttttcaac
     1381 tgctaattgt tgttctatta aacctttttg gaatgttggt attttcccta ttgataatgg
     1441 ttcatacccg tcttttccaa ctatacatgg aatttcaacc atagcatcat cttgtatatt
     1501 ttctatagct ccattatttt gaactatcaa taacatacgc tcctgtgtat taaaagctag
     1561 agctgtagct aaatccacta taaactctgc atgtattcct atcttaagcc cactgccctt
     1621 agaatgtcct tgtttttcta tcaatgcaca tgaaccaaaa acttcttttt ctcttccatc
     1681 aataacttca ttggcacgag tataatttac atcagaatga tttacaacat aatctggaaa
     1741 tagatagtac tttaagtaac tacttggtat tgtagttaaa tctgttttta ctatttcttt
     1801 agtaaataaa ttagtttcaa accaactatc tttcttgtca tttttcattc cttcttcacc
     1861 atttataaaa ccatattctt ttatatgttc tactaatttt ggtaaaagtt catttccttt
     1921 tttatcttta attgaagtat accaaccaaa gtgatttaat ccaaagtatc ttatatccat
     1981 atgtttacga gatttgagtc ctgcaatcct tgctatatta tgttccatac ctattggcat
     2041 atcacaaata tttattaccc tagaattagg tctcaacctt ctaacagctt ccgctattat
     2101 tgatgctgga ttagaataat ttaacatcca acaatttgga gaatactttt ccatataatc
     2161 tatgttttca agaacacctt ctatagacct cattccataa gctattccac ctggtccaca
     2221 agtttcttga ccaactaccc catgttttag aggtatcttt tcatctagtt ctctcatttc
     2281 aagttttcca actcttatat gagctaaaca aaaatctaca tctgtataag cctctttagg
     2341 gcatgttgtt gctaaatact ctatattagg gtccttttcc tttattagta tttcacaagc
     2401 tttagctacc ttattttgtc tttcttcatc attatcatat aatttgattg ctcttaatgg
     2461 taacctatct aagttatcta gcaacattaa tatgatttct ggggtatatg tacttcctcc
     2521 tccagctatt actactgaaa atttttccat aataatatct ccttttctat ttaaaaattt
     2581 actgtattta taaataaatt tataaatact agtactttaa agtaaaaggg agttcattta
     2641 ttaaatctat tgatttaata aactatagcc aaacttcaag cactatttac aagaaattta
     2701 attcttatta attcttgggt ccatcatctc aaatatatct acaagttcag atactaaaga
     2761 atgagcaaat aatgcatttg aataatggtc ttcagagtgc acaactaaaa aatcagtccc
     2821 actatcttca ctattcatag catttgatag taattctaaa tgatgctttg atgctgtttg
     2881 tattttctct gaggctgaat ttaaaaggtg ttttgcttta ttgtagtcac ctttttttat
     2941 ttccttaaga gacatcatta catcactttt agcatctcct gcttctgata ttatactaaa
     3001 tactttttct tccatttcag gtaccatatc cttctccttc taatgacttg ttaaaaatca
     3061 aagctatcat catctaatgt tgtagctaat tctgcatttt tatttaattc ttccttctcc
     3121 attatcttaa agaatggata atatatcaag gtcataagta ttatacttgc aaatactaat
     3181 acgattgcct tccaatctaa tgtcatcaaa aatgctgcaa cccctggagg taaaaaacct
     3241 ggtggttctg caataggtaa tcctactaat cctactttta atgccataaa attaagtgct
     3301 ccaaccaata caggtccaaa tacaaatggt acaaacatat atgggttcat aactattggt
     3361 gttccaaata ttactggctc atttattcca aatagtgatg gtaaaatcac aacttttccc
     3421 atactattaa aactcttaca cttacttctt gacataaggt acactaatcc caaagttatc
     3481 cctgaaccag ttacttgcaa gaaaccatag taaaaaccta ttgtaaacac atattttggg
     3541 tctcctcctg ctgctatcag tgttgcattt tctgccatat atgtagctgc tattggcatc
     3601 catatacttg aagttattgc tgctccatga agcccaaaga accataataa ttgagttata
     3661 aatagtatta tagttactgc aaaaacatta tctacactgc ttatagctgg tgctaagaaa
     3721 ttcattataa tagctggtag tggttgacct gagacatttt tagttattgc tgctattgct
     3781 gtaaataaca ttatacatac tatcattgga gttaaatttc taaaactttt atttactaca
     3841 ctaggtactt cttttggaaa tctaattacg agatttttat cattcataaa cttagtaata
     3901 tcaactacta aaagtgctac taatatactt acaaataaac cttgtgcatc taaataactt
     3961 gtatctaata caccatctac tacttgtcca catacaacaa gttgtgcaac aactgctgtc
     4021 atacctattt ctacatgatt aagattatat tttttagcta gtgcctgagc tataaaaaat
     4081 gctgaatata tagataataa actcatagta aatttattag ggataagtaa tgtatccata
     4141 ttttcagata ataatgtttt tgcacttcct tcaggtaaca tattgtttaa tgccataaat
     4201 aacatactta aagaaccaac aattattatt ggggtaatgc ttatcatacc ttcttttata
     4261 gcttgaagat gcctttgttt ttcaatcttt tgtgctattg gaagaagaaa tcttcttaaa
     4321 ttattttgaa gtgcttccat ttttattccc cccaattatc tatttttata taattcgatt
     4381 gccgacttca taacagaagg agcatccata cgaccataat gcttagtatc tattaaacca
     4441 actgctattt tgtaattctt acaagcttca actacatcat cttccttaaa cctaatttgt
     4501 ggtgctacaa gtactacatc tgtatcatta gcttcaatgt atgattttaa attttcaaat
     4561 gaggttgcct ctatatttat agttttagtt tttaactttt catgctcact acaaaaactt
     4621 ttcatctttt ccacaagtac acctgttgaa gctccatttg cacatactaa taaaatattc
     4681 ataattaccc tcctacaata tctaacctct tttgttttct aattttttat cagccaattc
     4741 ttactctaat tcctatcagt ttttacttta attcttatta ttttatttta attcttatta
     4801 atatttactc taattcttag tactgccaat gattaaactt gaaagccgta tctataactt
     4861 cttcttgctt atatttttct aatattttta agtatctttc tttataatca ttatctactt
     4921 ctttttctgg tattactata ctagcttcat ttaaaaagtg gaatgaatcc cttcccattt
     4981 ctaatcctct atatgtatgc ttgtcaagtg ccacgtccat aacttctgga actttaccca
     5041 ttgcaaatcc ttttataatt atatttttta ataaatcact tgatctatct ttctcacatg
     5101 cacaaagata tcttattgca tgtatgaaaa ataaaggtct gtctccatct gcatatgaat
     5161 attcctttct tacttgattt aaattattta tgattattac agctgatggg tcccccattc
     5221 ctatatcttc aactgatatt gtaagtatcc ttctccatag cttatcttct aattctggtg
     5281 atgatatata tagttcataa gcaaattcac aagcttcttc caccatattt cttcttatag
     5341 ctttttgaaa tgacgatatt atttcgtctg cactaaatcc gtttcttgta gtcattcttg
     5401 cccatgggtc atttgccttt ttatctctta atattttatc ttgcatatta tttactcctt
     5461 tttatttaaa ttttaattat ttatattact catttaataa tataagcaag tattatgcca
     5521 gtttttttag acactttaaa acactgttat ttcaatcatt tttatcatca aaacttagat
     5581 actttgtcta agtatattta tatgtgtcta atattaatat tattttagac taaaaaaaat
     5641 taccaaataa gtttttatac tcattggtaa tctttttcga ttatttctgc atattctaat
     5701 attaataata tttgatagca ctctttttca ttaatttcta tattatattt tttatctaat
     5761 tgagatacta tatcttttat tttgcttagg ctcttgtgat aatcaagtgt tttttcttta
     5821 tcaagctttt caatttctct agtatttcca atcaacccat ctaccatgaa agctaaatgc
     5881 atcataagtc caattacttt atcgtatttc ttttctatat taaatactaa aaacaattca
     5941 tcagacacat attttatatc tttaaatatc ctattataat tagagctttt taaggatgtc
     6001 tttaaacctt caactacatc atcataacct atacttatct ttataatatt ttttaattta
     6061 ttgatatttt catccttatc tatatctttt ttgctaatat agtcaattcc tctaatatta
     6121 attctttgtt cattgattac tgcaacaata ttactacttt ctttaagttt cgtaatattt
     6181 aaacttaaat ctttttctgt tttatatggg acagatataa tatctattcc atctaagtac
     6241 ctactcatct tttcttctaa tatttttctt gttttattat ctacaccttc tgaaacatgt
     6301 gatgctataa taattgtttt agacagattt tctttatttt gaatttcatt agttccaaaa
     6361 tagtactttc tcgtgttagt tatagagttg tatacgtcat ttaaaggtaa tcccatattg
     6421 gccttctgaa ctgcttctaa cacagttaat gttgtcacca taggaattac tcttactcca
     6481 cacttttttt ctttctttat aatttcatca aaagagttta atgaacccat atctgtaaat
     6541 agtaatacat ctttattgtc tatattatta attaaatttt taaaatctac aataacttca
     6601 tcatagcttt tatctaactt catatcgaaa gaaatagcac tgcactttcc aataatatca
     6661 ccaactgctt ttaccatact acttgctgta gtttctccat gcatagcaac tataatatta
     6721 atgttattca ctattttatt ttgttcatct tgtttagctt gtactatgaa taatgtaata
     6781 tatgctacag tttctataga taaaaataaa tcaaattcat tttcaattat tccaactatt
     6841 tttagtgctg ttttaaattc acttctgtta tttcttctaa tttgattcaa atctatgttg
     6901 tttgtagagc tacttttatc caatacgctt tttatataaa ttgccattga cttaaatatt
     6961 gattcactta tgtctatttc ttcatcttct ttaataattt gtcttattga ttcacacatg
     7021 cttttaaact taacattatt aaatagagaa gcatctgcta tattcatttc tacagattta
     7081 ttaagattag tatttactgc attaataata tttatatcat tgtagttaat aacttcttct
     7141 tctcctaatg acgtaaatac aaaatattct attccatgtg ttataacttc atctgcttta
     7201 atagacttct ctctataatc atcactcact tcatttatag atttatcaaa atattttttc
     7261 tctatataaa ctggttcttt attatctctt ttatatctta ggtatccatt tgcaacagct
     7321 aattttatat cattttgaag ttgacctaca ttatttttac aatcataaag taatagtgat
     7381 ttaattattt ctttatgtac ttttattgaa atagaaatac tttttgattc ttccttgaaa
     7441 aaatttttga ctaattccat tctttcaatc attgtcctat ctctcagtga tggtatttct
     7501 attttcattg gtattcttct attgaatgta tctaatagtg ttgatgtcgg attttctgta
     7561 gtagcacata ttattaatac cttagactct ctttctttcg ttgcatctcc tagtctttta
     7621 aatgttccct tatctataaa agtaaacaac atttcttgac cttctgctgg tagtctatga
     7681 atttcatcta aaaatagtat ccctccattt gcaatttcca aaagaccttt tctggaagat
     7741 tctgcacctg tataagctcc ttgttctacc ccaaaaatat gtcccataag taattgtgca
     7801 ttattagcat aatcagcaca attaaatgtt acaaaaggag ctttattttt tctaattcca
     7861 ctatctatag aataatcgta catatatcta gcaatcatac tctttcctac tcctgtttct
     7921 ccatagataa tagtatgaag tccatttgta ggatagagca ttgcgacctt gcatttttct
     7981 attataggtc ttaaactatg ttctttacct attagtgttt caaaactatc tttttttatt
     8041 ttgttttcta cttttgttcc tttttttatg ccaagcaact cactttgtgt atcaagcaat
     8101 tcattcttgt taaggttaag atttgcaggg atataataca caggtcttcc ttttatcttc
     8161 gtaaccatac cctcattgaa taattggttt aaatatgtac ttatattgtt tcttgcaatt
     8221 cctgtctttt ctgataattg gttagctgta atcccttttt cattttccct atatgatgat
     8281 tctaaaactt tcattacttt atctttttta tatatcatta caagctcccc tacattatag
     8341 tattttatta actaaaaccc ctatacacac tttatttttt aataaactct tattctttaa
     8401 ctaaggttat aatttatcaa actttcctta ctttaaatta tagaaaatta ttgtagaaaa
     8461 aataagatta ttgctcattt tttctacatt actattttta attttatagt actttcttaa
     8521 caacatactt tacttgtttt taattttatt atatttgaat ttattatatt tgaaaagtag
     8581 aaataaaaaa ccctattttg gagtagtttt aaaatttctc caaaaatagg gttttagttt
     8641 gtatttcaaa taaatacctg ttcaagtatt tttatactaa acaactttta aattttgttg
     8701 atatttattt atttctgatt tagaagaata tacaaaatgt ccatctgaaa cctcaatcca
     8761 acttaatgac ttttcatttg aacaatcata tccattagaa ttatactcta ttctatttct
     8821 tgacttagca tatctagggt caggaacagg aattgcagaa agtagtgatt ttgtatatgg
     8881 atgaatagga ttattataca attcatttga atctgccaat tctactaatt ttccattata
     8941 cataactcct atgcggtcac taatatgtct caccatagat aaatcatgag ctataaataa
     9001 acaagttaaa ttcttttctt gttgcaattt tttaaataaa tttactattt gtgcttgtat
     9061 agacacatcc aaagaagcta taggctcatc agctattata aattctgggt ctactgaaag
     9121 agctcgcgct atgccaatac gctgtctttg tccacctgaa aaatcagatg gatacttatt
     9181 tgcataactt ctatcaagtc ctactagctt tagcatctca tatactttat tcattctatc
     9241 tgttttattt ttacagatac cttgaatttt tagtggctct gaaattatat ctgcaattgt
     9301 catacgtgga tttaatgatg aagtagaatc ttgaaaaata atctgcatac ttttgtttac
     9361 atcttttttt ataaatttgt acgttttttt atctgatatg caatttcctt tgtaaattac
     9421 ttctccacca gtagattcat gtagtcttat tatagtttta ccagttgtag attttcctga
     9481 acccgactct cctaccaatc caaatatctc acccttatat atatcaaaac ttatatcatc
     9541 aactgctttt acagtagtac ttttgtccaa atgaaaatat tgctttaagt tttttatttc
     9601 cagtattttt tctctattca ttagaaatca cccttccaca atttactcta actggtacat
     9661 ctacttcagg tgcatctggg tgcaataacc aagttgctgc actatgtgta tcattaattt
     9721 taaacattgg tggctctttt tcataatcta tcttaagtgc atttttattc cttattgcaa
     9781 aagcatctcc ttttggtggg ttcaataaat ttggaggcat tccaggtata ttatataaat
     9841 agtcatcctg cgaatctaaa gtaggtaatg aacccaacaa cccccaagta tatggatgtc
     9901 tagggtcata aaatatatcc tctacagttc ctatttctac aatctttcct gcatacataa
     9961 cttctattct atcagctata gttgcaacta ctcctaaatc atgagttata aatattattg
    10021 acaaacctat tttatgttgt aaatccttta ttaaatcaat tatttgagct tgtatagtta
    10081 catctaaagc agttgtaggt tcatcagcaa tcaatacatc tggattacaa gcaagtgcta
    10141 tagctattac tatacgttgt ctcattccac ctgaaaaatg atgtggaaat tgtttaaatc
    10201 ttttctcagg attatcaatt ccaaccaatt caataagctc tatggctctc ttttttgctt
    10261 cacttttact tataccttga tgaatgatta cagcttctgc aatttgcttt cctattgata
    10321 tagttggatt gagagatgtc atagggtctt gaaatatcat tgatatattc tttcctctta
    10381 tatcttccat ctctttttca gacttcttaa ccaaatcact tgatttaagt aaaacctctc
    10441 catttttaat atatccattg tatgggagta tcctcatcaa actcttacac agtacagatt
    10501 tcccacaacc agattctcca actatagcca atgtctcacc tttttttaga ttaaaagata
    10561 catttcttac agcctgaact tctccttctt ctactttaaa acttacagat agattattaa
    10621 cctccaataa atgttccaaa aaccatcaac ccctatgcta ttcaaacctt agggatatat
    10681 ttttatccct aaggtttcta attaatttca gtattattca attgtccagt cagctatgtt
    10741 ccagaatata cctacaccat gatgacctaa aactgtatca ggtgttaatc cttttatgtt
    10801 tggttttcca acatatattg catctatata agcaataaat gtataaggca tatccttagt
    10861 catttctact tggaattgtt tatataactt taatttttca tctttatctt ctgtttctct
    10921 tgctttttga agtattttat ctatagtagg attagagtaa gcactgtaat ttgcaccttt
    10981 atctgttcca aatactttat atgtatggtc atctgggtca aatggacttc cccaacctat
    11041 taaatgagca tcttgattag cccaatctgt ttcagttaca acaacagctt tagcatcaac
    11101 accaatttct tttaactgtt gtgcacatat tttagccata tcaactctaa cttggtcact
    11161 ctcacctgct gttatctcga aagctaactt agtaccttct ttttcataga ttccatcaga
    11221 acctaatttc caacctagct tttcaatttc ttgtttagct ttttctggat tatattcaaa
    11281 cttttctata tcaggattat tatatggtcc catttgtaaa ggtgaatatg ctggtacacc
    11341 atgtcctaat aatacactgt caactattgc ttttctatct attgcatagc ttaaagcatt
    11401 tggtaatcct ttagcttttt tatctttaaa gaatttagaa ttaaaattgt ataatatacc
    11461 tctatagtcg gctgttttca ttatatttac tttaaaattc ttttcgtctt tttcaaagtt
    11521 agacatatct ttaggagtta tttgagctag gtctaattct cctgatttta attgcattgc
    11581 cttagcctta tcatctggaa caatcttaaa gactacttta tctaatcctg gttcttttac
    11641 aaaataatca ctattcttaa caagtgttat actttgacct ttgtcccatt tttcaagttt
    11701 aaatggtcca gtacctattg gtttttgatt aaattcatca gtagctatat ccttaccttc
    11761 caaagcatgt tttggtaata ctcctactgt taaataatca agcattgctg tatttggagc
    11821 ttttaaagta atttttatag tattatcatt aaccacatca atttttgtta tatcttcata
    11881 atttgatgct atctcagaag cattatctgg attcattata gtttctattg taaacttaac
    11941 atcatttgct gtaaatttct ctccatcatg ccacttaaca tcatctctta aattaaaagt
    12001 atatgtattt gttgcctcat caaatttcca gtcctttgct agacaaggaa ccaccttatt
    12061 attttcatca tgagctgtta atccattaaa tattaacgaa tttatttctc catgttcata
    12121 tagtgcagga tttatacttg tatagtcatt acttccataa acaagtacct ttccatcttt
    12181 aggcgtatct gccttcttat ctttgtctcc tccactagaa caacctgcca ttagactaag
    12241 tatcattact aaacttaaaa cttttaactt ctttaatttc atgatgctcc cccttttgct
    12301 ttttataaaa tatttttcaa agctttgacc ccatttattt aaatagatat ttcaaatacc
    12361 tcagtatttg cttatttagt actcaaatgc tgatttataa attactagat tttttattat
    12421 tattctttct tatataatta cctatatttg ttatacacac caatgttgta accaaaaata
    12481 tacccggaat cagtataatc caccatctat ttgaaagtaa tgcttcctct gacaaagata
    12541 acatacttcc ccaagaaaca atttctattg gtaaaccaat tcctaaaaag ctaagtgtcg
    12601 attcagtacc aatagctgcg cctatgtttg ttacaaccat gaacattatt gatgccacaa
    12661 aatttggaag taaatgttgc tttaatacat agaagaatcc tcctcccatg ctcttagctg
    12721 ctagtatgta ttcgctattt tttatttgtc taacttctgt tctcactatc ttagatatat
    12781 tcatccaact tgttatccct attactatgg acatagatac tggatttgaa tttccaagta
    12841 tagcttgtac aaatattata attaatattg aaggtatact aagtatgatt tctgtaaacc
    12901 tcatcattgc atcatctaca agttcagatg ctgaaccact tatactacca taaacaattc
    12961 ctataacagt tgatattaca gtggaaaata gtcctataaa taaagatatt tttcctccat
    13021 accatatcat agaatatata tctctaccca ttgagtctgt tccaaataaa aaagttttat
    13081 ttggagctaa attagaactt gctaaatcca tgtatgttgg ttcatgtgtc attataaaag
    13141 atgagaatac acttccaatg actatgattg ataaaataat aattgatata tatggtaatt
    13201 ctttaatttt tttagataag gttttctttg tttctatatg ttcatcttct gctactaaaa
    13261 tataattttc tcctacaatt tcaaaatcac tatattgtgg cttcattagt atcacctcta
    13321 tcatatttca ttctagggtc tattttattg tttataattt gagctaacat attcccaaat
    13381 actactaaag cccctgttat taagcataaa actaataaca tattataatc atgatacttt
    13441 gcactttcaa aacaaagtgt tcctaaccca ggataagaaa aaactttttc aactacataa
    13501 gttcctccta gtatatgagg tatcgaaatg gccattatac taatatatga tggcattata
    13561 tttctcaggc aatgcttaaa aacaatagtt ctattattta aaccttttgc tttacataaa
    13621 agcacataat cttctcttat ttcctctagt aatttatttc ttatcatata tgtgtaatac
    13681 catagatggc ttaatataag tactgtaaga ggtaagatta gatgtgatat cctacttaat
    13741 atactggact cttctcccat tgaataagca ccactacttg gaagtatact taagtttata
    13801 ctgaatataa gtatgagtac taaggcaacc caaaatgatg gaatacagtt ggttattgtt
    13861 cctaatttgc atatgattct atcaatgagc ttatcttcat gtaatgtaca aaatattcct
    13921 aacaataagg ctagcacaaa ggtaagtata tatcctgaac cacctaatat tatagtgttt
    13981 atatagacat catttataac agaagtaaca ttttgtttat atttaaatga aattccaaat
    14041 tccccttttg atgcatttga aatccatttt atatattgac tgtatattgg ttcatccaaa
    14101 ccaagttttt tcatagcatt ttctttttct tgtgtactca ttctttctac tccatcccca
    14161 tagtaagaga ttaatgggtc tcctggagca agtcttgcca tgtaaaaaac aataaaagat
    14221 aataaaaaca ttactaaaat aaactgcaac aactttttca gtatatcctt taacaaaccc
    14281 caacccccct ttgttgcaat aaaaaaaacc acataaaagc aaacgtaaag taacgttaaa
    14341 accttcgtgg ttccattatc attaaacaaa attaaatttt ctatatttat ctatgagtta
    14401 attttagcat catttattaa ctgtgtaaac aaacttttta aaaattgtta aaatttcatc
    14461 aaattatttt atttatacct aaaataaaat ttttatattc tattcttcat tattttctat
    14521 aaaattataa aattttaggt tgactatata agaaaagtat attatattag tttgtatgca
    14581 aaccatttaa gaggtgattt tattgaaaag taattatgac tgttttagaa tagccatgct
    14641 cttaaaagaa ctttattcta aaactatgta cacagtagaa gaaaatttta aagaaaatgg
    14701 attaacacac caacagatta tagttataaa actgatagct cataatcaag aacttacaat
    14761 atcacaacta tgtgatgaaa tgtctttagc taaaggtacg gtttcaggca taatcagcag
    14821 attagaacag attggatata tagaaaaatt caagaaatct aatgataaaa gaaatacata
    14881 cgttaagttt acaacaacag gatttgaatt tgccacaaat tttaaaatta aaatgcaaga
    14941 aagttttgat gatattttta aaaattgtga tgaaaacgaa ttgagtgact tagtaaaaaa
    15001 tcttagaaat atattggcaa aagtaaagga gagataatta tgaattataa attaatactt
    15061 gcaatagtat ttataacatc agctttaatt ttctacacta taggtgtatt tggagaaaga
    15121 aaggcaaaaa ttttaaaaaa gaaacatgta attatatttt ggcttggttt tatatttgat
    15181 actttaggaa catttacaat gagtaacata gccaacagcc atacttttga agtaaaatct
    15241 gctttatcac aaaaccttca tagtattaca ggtcttcttg caattgtgct tatgcttttt
    15301 catgcaagtt gggctacttt tgtcctatac aaagatgatg aagaaaagaa aaaattcttt
    15361 cataagttta gtatagttgt atggactata tggttagttc catattttat aggtatgttt
    15421 attggtatgg ctggatagta aaataaaaag tgtgtaagaa atactgtagg taaatttgta
    15481 taagacaaat ttacctacat ccttctttca cacttttaca tatttattta taatactcca
    15541 ttatttcttt catgtttctt aatacctata tagaatattt aattgtttct atagtatttt
    15601 attattttct cacacttttt catatatata ttgttttact atttcttcat atgtatatat
    15661 gaaatattcc attatttcta taaatgtttt attatctttc tcatactttt tcatatatat
    15721 attgcttcac tattttttct tatttcttca tatacatatg aaatatttca ttatttctat
    15781 aatgttttat tatctttctc atactttttc atatatattg cttcactatt ttttttactt
    15841 ctttattaaa tacttatgta taacatacat ttaataaacg ctaactatta aacacctaat
    15901 acttgagtta ctcctggaac ttcactcacc aaaacatttt caataatagc tttgattgtc
    15961 atagtcgctc ctggacaccc actacatgcc ccttgtagtc taactaaaac cacaccattt
    16021 tcatttacat ctataagctc tacatctcca ccatctcttt gtaatactgg ttttatcttt
    16081 tcctcaagca ctttctcaac tttttctctc atagctattc cccccagaaa tattttatta
    16141 ccaaaattat accaatggtt taaatttttg tccatctaat gatttatcaa attcaatttt
    16201 tgcttcatca ataattttag tatccataaa tacatcataa gcactacaag ccagtacttt
    16261 agctgaattt atcatagcag aaaatcctat atttgaacct gctgatgaac atgactgcca
    16321 tgtatgactt gcaattccaa taggccaagc tgccattgca aattgagcca ctggtattac
    16381 ataacttaca tctccaacat cagtagaacc agctagtcct ttatctttgt caccgtcaac
    16441 tatttccttg tgtatatagc tttctacaat agatttatca ttttgtaatg atgttgctac
    16501 acctaatctt tcttctctag taagagtatc acacaatttt tttgcaaatt cttcttcttc
    16561 aggagtattt ttagggcaac caacaaaaac catattgtca taaactaaat cagtcaaaca
    16621 ttggtttggt atatagtcat atattccatc tgtaacctta tactccattt cagtttctgt
    16681 catcattgct gctccttgag ctacttttat taatctatca agaacgtgtt ctgcatcctt
    16741 tgctttttta cctctaataa agtaccaact ttcagcaaat ccaggaacta cattaggtct
    16801 tccaccacca ttagttataa catagtgcat tcttatagag tcaataacat gttctctcaa
    16861 ataattagct ccaacattca taatttcaac agcatcaagt gcgcttctac cattatgagg
    16921 agcttgagct gcatgggctg ttatcccttt aaatttaaat tttacagata agtttgccag
    16981 acttcctcct ctccaaggtg catttatatc aaaaggatgc catgtaaatg cacaatctac
    17041 atcatcaaaa cagccattta tacacataac tgtctttcct ccaccttctt cttcagcagg
    17101 acaaccaaaa tattttattg ttccattaaa tttattttct tctattaatt tttttataga
    17161 aacaactgct cctacacctg ctacacccaa caggttatgc ccacatccat gtccagcttt
    17221 tccttctacc aatggctttc tttctgcact cacacattgt gatagctctg gtaaagcatc
    17281 atattctcca agtatgccaa tcacaggttt accctctcca aaacttgcta taaatccagt
    17341 aggtaaattt tctacttctt caattttaaa tccttttgac tttaggtatt ctttttgaat
    17401 gctacttgca tacttttctt caaaggctaa ttctggattt tcccatattt tcttagataa
    17461 atcaattaat tcttctctta tttcttcaac attatttatg atatactctt tcataatttt
    17521 cctccaaata tatgtatttt tgatatgctt tacagattat attatatact aacattctat
    17581 ttattcacaa ttttttgtta attaatttta ttcatatgct cttctatgga gtatatctta
    17641 tcttcacttt gcctcttcat aaatttaatg tactctatct tccataaagt agtttcagtt
    17701 ttctcattta acataaattc taatatatta atttctctca ttctaatatc ttcataaaat
    17761 actacactac ccaatattgc caattctaat tcacttaatg atgcaaacaa cattaaatac
    17821 tcttctccaa ataaacattc agattcaaga atatcgataa agtctttttt agcattgata
    17881 ttttccttta ttattcttat tttttcaatt atagatgtac tatctaatat ctcattgaat
    17941 atctctctaa acgattcatc atccaattta ctttcatcat caacaatata atcttctaag
    18001 tgttcctttt tatttttact cacagttacc atacttttaa aagtgttact ttttattgag
    18061 cttaacacag attcaataaa tatcttttca tattttttaa tatatcttat tacatcttca
    18121 tcttctatgc ttaatctttt tattaatact tcaattgctt ccataagtag taaagttatt
    18181 tttttattta ttctaatttc tctgttaatt tcttcaaaat cattataatc caaattacta
    18241 tctacttcag tgttaaaact atcatctact tcaatcaatt caattatatt actttcttca
    18301 gagcctataa ctttatcttc agtaatatta ttgtacatat ttttaaattg tttttctaaa
    18361 aattcatact catattttga aatttctaaa ttagtcactt catttcctaa aatagtagaa
    18421 aaaatacaat tatttataat aagttcaaat aaatttacaa gtataacatc acaatctatt
    18481 ttataagtca ccccatagtc ataaaataat ttttctctat cttttttctt aaataggtta
    18541 caaaatctat tttctatatc tatactctca atataattcc tcacataata aataccctta
    18601 acatccatat catctagtgc caatggataa tctatactta ctggaacgtc ctgagcttca
    18661 aattttacaa tataactttt aaagaaactt gataactcca tcaaggtatc attatatgct
    18721 attgaattag tatccaattt tctactcatc attagtttat aaaaatcttt tagcctaact
    18781 aactcttcct ctaatatttc aatgcctcca aggtacactt ttttaacatt cttagcagtc
    18841 aactccacaa ctcttttttc tatatctcca agcttattta tatatgcatc aatagcatac
    18901 catattgaaa tcaacagttt ttcggcaact tctgttttta ctgatgtgct ttgaccattt
    18961 gtatattttt taatcaaatc cataagtatt agagatactt cttgttgtat attatatact
    19021 tctctttcat ctatcacttt acaatttaga cattccttaa gtagagatat ggaatattgg
    19081 ttctttatta aattattttc gtttatatta atattactta aattatttaa catacaaaat
    19141 ctctcctatc atatattaaa cttctccaaa tttaaatttc tttgcaaatt cgtctgcttc
    19201 tcctcttaca ttgtccatat tgcctgaaaa tttttcataa aattcaccca gtatttctat
    19261 aatctcatca tcacatatct tgtcatcagt ttcatttttt aaataataaa aaatttcttg
    19321 catatcatta atagcctcta aataattgtc cacatttgta tattgtgatg tatatatatt
    19381 ttctattaac tgttttgtaa cttttatatc taattctatt cttccatacc cctttaaagt
    19441 attatctctc gaatttatta tatcttttac atcagattca gaaagagcta gaccataatc
    19501 tccagattct atattagttt caagcagttc atttctttct atttccttta aattctgatt
    19561 tatagaactc aaaataatag gtgatatcat ttttaaattc tcctttttta ttttttccat
    19621 tgactttttt tgttttttat gctatattta aattattata tattatttta ccaaccactt
    19681 ataatagtag tgttaaaagt ggtttttgtc aactcaaaat tactatctca attaaacttt
    19741 tcaattttct caacaaaaaa ataccatcat ttagatatat aattttctat aacaactttt
    19801 aattcagtag ttatttacta aaatctaaac aatgatatat ttattaattt tatttatctt
    19861 ttttggctct acttctactt ttctttacat ttgagcaatt tctacaagaa ggtgaacagt
    19921 attgagattt agaatttgta ggaatataaa ttttaccaca gtacttgcat ttatttaaag
    19981 aagaaggttc acttgtaatt gcaaaggcat agatagtctc aatagctgtt ttcaaagaat
    20041 caaactccca tgcaataatt ggtttatcta attggcttat agaaaatcct atcttttgag
    20101 gattaaaccc tccagacata atagtaacac tttcagttaa tagattagat gtatttttat
    20161 atacacaaat ttgattaaaa tgcttacaca tatctttagc aaaacttaca atccaatcta
    20221 gttgttcagt gtagaacttt gaaaatacta aatctaaaat caatggtctc tttccaaaaa
    20281 actttggaga ttcttctctc tttgatacat ctatacccct tctatacttt ttaaaataca
    20341 catcttcatc acttgcaaat ggtataaaca tgtttacata ttcatctgta ctcaatatat
    20401 tctcttttgt aatataattc ttttcaatca tcagtactct ttcttctcca actatatctc
    20461 tattatatac acttgaatat attaaaccca ataatccata cttttttaca aattcaagta
    20521 cttctttctt tagtttcatt tcttttgtct cttttgatat atcttgtaat gcctcttgtc
    20581 ctatgcgaat tatatctact attatatcat ctgctacatc aaatgggtta tacatggtaa
    20641 acacagcatc ttctgttgga actatatata attcatcttc ttcagtaatt ttatattcat
    20701 aatcactata cctaatccaa tcacttgcaa aattccctat taattctatt tttttattca
    20761 taataatcat tcacaccttt caatgtaata tataatttta tattactatt acacttttag
    20821 tttattccat attttctaca ctgtcaacta ttctttttat atttttagca tattaaaatt
    20881 tataatagcc tttataatgg atttctacag ctaaatttct tgtttattga tgactaattc
    20941 ataattaaat ttataaaaac tatttacata taaaattaat ctctttataa ttgatatgta
    21001 atatattttt acacttacat attacatatc aattataaag agaggtattt aaaatcatgg
    21061 atagaaaacg tgaattaaaa caattataca aagaaatgaa atttgacaca ggtgtattca
    21121 taataaaaaa tgatattact aaaaagattt tccttggaaa aagtaatgac ataaaaagca
    21181 aatttaactc tctcaaattt cagcttggtg ctggctcatg tatgataaaa gaattaaata
    21241 atgaatggaa aaaatatggt gaaaaagcat ttacatttga agttttagaa cttataaaac
    21301 atgatgataa caaaacagag aaagactatt tagaagaact agatatttta gagatggttt
    21361 ggttagaaaa attaaaggaa gataatactt atgaaattta ttccatataa aaaataatat
    21421 aagaaaagta gatagtgtct caaaatagac atttagttca taagatactt ttttatataa
    21481 aataaagtat cttttcataa ttttaacaat gaaaaagagg cttatctcca tttgatagcc
    21541 tcttcccata tattttatac cattataaaa tgaacaatct actaattttc aatgtatata
    21601 ttcattttac taataacact ccattacttc tttacagcat ccaaacattg ctctataata
    21661 ctcttatcac ttatacctat tgctgttact ttactagctc cacttaatat actcttatca
    21721 cttttatttg aaactaaaac aacaggagca ttttttgcaa gtggtgatgc aactaaagca
    21781 taaactaaat cgtctccact tgttatatag aactcttttg ctccattata gaacttttca
    21841 ataacatttt tattagtttg atatctatca acaccgccaa ttctagttgc tctatatctg
    21901 ctcactatgt aatcacttaa tgtagactct cctccaatag catatactgg aacaggagaa
    21961 actccaaacc atgggtctaa gtctgtgtct tcttctgctg aaggtatatc ttttgtcaat
    22021 attataggag ctccatctct ataagcaaca gatgcaacac ttactgcatc agcttcatcc
    22081 ttaaatccat ttactaaaaa catcttatca ctgtttttaa ttttttctat ttcgcctgca
    22141 attttataac ttgtatctac tctatctaca ccatcaattc ttataacttg cattcttctc
    22201 ataagtaaca ttttttctac atctttactt atagaatttt ctccacctat tacatatatc
    22261 ttagtaactc tattcagtct ttgaagtgtt gcttctggta tatcatcctt attagttaat
    22321 aaaatagctg cattatttac tcctgcaaga ccacttgcag caattccatc taccattgta
    22381 gagtctgcat tgataagaac tgctgttgta aaatcttgct tatctgaaat aagcccagct
    22441 gtttcatatt tatctactcc ttgaatattt tcaatcttat ctagtgcgtt tattgatgtt
    22501 ggaaaactaa cacttaacag taatgctgaa atacctaacg ccaatacctt tttactaatc
    22561 ctcataaatt acctccctaa aacaaatata tttagtatta gtataatata aaatcattta
    22621 aaaatagtgt aaaaatagtt acactttttt ataatttaaa taattttaga ctaaacacaa
    22681 ttcatccatt aaaataactt catttattct atatgctaag ccatcccacg ttttttttga
    22741 catatctaca gatgttttct tatttgagtt attcaataaa gattgtatct tagaatctat
    22801 tgcattatac aaattatttt caaaatcata taactcttca tcttttggaa taccttcttt
    22861 ctccataaaa ggtagagaaa tatattctat ctttccagaa ttattaatct cactaccaat
    22921 ccactcttta acaccaagaa tatcagtagt gattacatct gtgccacaag ataaagcttc
    22981 taaaactaca actggtaatc cctcataaaa tgatggtaac acaaatattt gtgacctgtt
    23041 gaatagctca gctaaatctc tctgttctaa ctttcctagg aaattcattt taaatggaga
    23101 cttacttgcc agtttaacta tctcattata tgattcgata tcgcttccag tacctgcaaa
    23161 attgacttct attaaatctt tactatattt taatttagat atagctttta taaatggaat
    23221 cagtcccttt gatttacata tcttacctgc aaatactatt tttattttat catcctttat
    23281 tttataattt ttattataaa atatatcatc attataacca ctaccaatta caactacttt
    23341 actttgactt actccaaaag tctttataat atcatatttc tgattttcat gaagagcaaa
    23401 tattaaatct aatttcctta tatttgctat tatgtattct ttctctaaat caatggtatt
    23461 taactgtctt aaacaagttc catgacaaat agacataacc tttatatctt ttaccatttc
    23521 cctaacaaat gcagttaaaa ggtacaaatg atgacatatt ataagttctg gtttaaaatc
    23581 attcatagcc ttatctatat ttactttaaa ttgatatttc aatctattta tcatgtctat
    23641 atttaaatct ttatatcttg tactttcata tggcatagaa tcactcatac ctacaacagg
    23701 aaaatttaac tccccacaat tatactttac tggataaaaa cttacttcac ttggaaaaca
    23761 atttacatca tcatttacat ctatacctgc aattacagct tgcttatgac cgattttttc
    23821 gaatcctttt atcataccag acaaatatat accactacct gtactatttg gtttttgtgt
    23881 tattatatga agaattttca cttttcactt gcctcctttc taaaattaaa tagttttata
    23941 cagtctaatc attatatata tctaaatata aacaagatga atcatctttt actttaaatc
    24001 ttggcacttt aaccgcttta tagtcattat cttcaaaatc ccttacttta ttatgtatat
    24061 atcctatacc aaatttttct gctatacgta tcaattcttc ttcttttatt agattatatc
    24121 tatcacatgc acttgtaaaa ccatcactcg ttagcatcaa ttgaaaatct ttttttattt
    24181 caatgtatcc atatatagaa ttttccacag cttcctcatc aaaatccaat atccaatagc
    24241 cctcttttgt atttttcttc aatctattgc ttactattgt atccataaca ctagttctaa
    24301 tctcatcaaa tgccatctct tccaagttag aaagtttact catttcatca aatacagtat
    24361 tatcaaattt acaaatactc ctatctttta taactttgga atctccattt ttaataaaca
    24421 aagcacaatc tcctaataaa aaatactcta ctttattttc atgaaatttt acaacaacta
    24481 tagaactaga tggtaaatct aatttttcaa ccttaaaccc atttaatctt agttcatact
    24541 ctttttttac ttctattatt ccagtattaa taatactctt taatgattct tctttattta
    24601 tatttttata taaataccta ttccaccact gaacatacca ccttgcgtca ctttcagttg
    24661 acactaaatt ttttccatta agtcctgtag caccatctaa aacccatgcc ccaaatggat
    24721 ttataccgac tacatcttca ttaaatttag ctgttccttg attacataat aggctatagt
    24781 ttcttatatt taaagccata tcaacctcca aattgaatat ctaaaaataa agttctattt
    24841 aaaattatac agcaaataaa aaaatctaca acaaaacttg ttgtagattt ttacttaatc
    24901 tatattatct ttatactttc agtattttaa tgatggaata atctattctt agtaaatgcc
    24961 atgactatgt tatacttatt acaagttaat ataacattat catcacgaat agaaccacct
    25021 ggttgtgcta taaaacttac cccacttctt tttgcacgtt ctatattatc tccaaatggg
    25081 aaaaatgcat ctgaaccaag tgctactcct gttaaagttt taagccatgc tctttttcct
    25141 tctccagtta gaggctctgg tttttcttca aaaaagtttt gccatatgcc atcagcaagc
    25201 acatccatat aatcatcaga aagatataca tcaatagtgt tatctctatc tggacgacct
    25261 atatcctttt taaattttaa gtttaatact ttaggatgtt gacgaagata ccaagtatca
    25321 gctttgttac ctgcaagtct agtacaatga atacgtgatt gttgacctgc acctacccct
    25381 attacttgtc catctttagc ataacaaaca gaatttgatt gtgtatattt taatgtaata
    25441 agagctataa ttaaatcacg ttttgcacta tctgtaaaaa ttttattatc agttggaata
    25501 tcttttaata ggtcttcatt tattaatatt tcatttctac cttgttcaaa agtaattcca
    25561 taaacatcct ttgtttcaat aggttcagga gtataatttt catctatttt tacaatatta
    25621 tagttgcctt tacgctttcc ttttaatatt tcaagggctt catctgtata tcctggagct
    25681 attataccat cagaaacctc tcttgctata atagttgcag tctccttatc acatacatct
    25741 gaaagtgcta taaaatcgcc ataagaagac attctatctg ctcctcttgc cattgcataa
    25801 gcacaagcta atggagaaag ctctaaatca tcaacaaaat atatttgctt taaagtatct
    25861 gataaaggta cccctactgc tgctcctgct ggacttacat gtttaaatga agttgctgct
    25921 ggaagacctg tagcttcttt taattccttc acaagttgcc aactattaaa tgcatctaaa
    25981 aaatttatgt atccaggttt tccatttaat acctctatag gaagttctcc attcttcata
    26041 taaatctttg atggtttttg atttggatta cagccatact ttaattctag ttctcttgcc
    26101 atatactcat ccctctctat aataaattaa tcataagttt gattaatcct atattaatta
    26161 aattattcgt actaataaaa ttatatggca tatttatcca ttaatcaact atatttttta
    26221 aaactcctat tccttcgact ttacattcaa ctatatcgcc atgctttaaa tatacttgag
    26281 gattcatccc catagcaacc cctgctggag ttccagttga aattatatct cctggcttta
    26341 gagtcattcc tcttgataaa tcatttatta tagtaggtat atcaaatata aagtactctg
    26401 tattagaatc ttgtcttact tctccattta ctacactact tatatctaat tttaaaggat
    26461 gttcaaattc ttctttatgt actatacaag gtcccataga tgtatgtgtg tctaagcttt
    26521 ttcctctaaa ccattgaaca tgtttatctt gaagtgctct ttcacttata tcatttacta
    26581 ttgtatatcc aaatatatat tcataagcat cttcttttga tatatttata ccttctttac
    26641 ctatgattac tgcaagttct gattcatagt ccaacttctc taccaaatct ccatgtaagc
    26701 ttatcttatc atccactcca attattttgt ctgctctctt agaaaaataa attggataat
    26761 ctggcataac tacgtttttt ataactccat ctgggatttc attgacatgg tctttatagt
    26821 ttagacctaa acatataata tcttttttag gtcttacaat tggggaacat aatttaactt
    26881 cttctaactt ataacacttt gcgttttcaa atgaattgtt ttttattttt tctaaatctc
    26941 ctgtagatac gttttcaata aaatcattca tatcagtata taatttactt aatcctaaac
    27001 tattaatttc atatatacta tttgtttctg aattaaatac acctattttt tcttcattgc
    27061 tactacaaaa agtcacaaat ttcattttta ttcctccatt caataagttg attaatatta
    27121 tttaattttt attagtttat ataaatt
//
LOCUS       DAEQAF010000048        26366 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.049, whole genome shotgun sequence.
ACCESSION   DAEQAF010000048 DAEQAF010000000
VERSION     DAEQAF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26366
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.049"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            169..345
                     /locus_tag="KRN00_002158"
     CDS             169..345
                     /locus_tag="KRN00_002158"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828023.1"
                     /translation="MNLKKKEKIVKPVLKKLTEIVLNILSKKILNYAIYAISVLIVTK
                     VVINIDLYISILYY"
     gene            446..1183
                     /gene="cas6"
                     /locus_tag="KRN00_002159"
     CDS             446..1183
                     /gene="cas6"
                     /locus_tag="KRN00_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBH1828024.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKVREYYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            1188..2654
                     /locus_tag="KRN00_002160"
     CDS             1188..2654
                     /locus_tag="KRN00_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828025.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFYELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIEPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDTVIKSN
                     IEIDKLDLTQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKISGQ
                     VESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKSFYK
                     KLLHEKISSIRLYRFDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREAANT
                     KNLGKKMIDNGNLSNLKELLLDNISFLKQSTGTSREMDFVSSSYNIGLYIKLCWIVDG
                     GEEYKMKNYMESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRAQLFQTIMH
                     VLVSNGILIGEGFVEGIMQSSELELNTNVGIFIQEIMK"
     gene            2674..3687
                     /locus_tag="KRN00_002161"
     CDS             2674..3687
                     /locus_tag="KRN00_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DevR family CRISPR-associated autoregulator"
                     /protein_id="HBH1828026.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYREKIHA
                     KTSIATITYDLRRMLHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKDKGSISKASPLRIIPFRSLNPYIGSTQLITNRGFLSSEFGRKYYDEKEENEVPR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEDGKLLLPEERKFMSKELREKA
                     VKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGVI
                     ETIESYSLKESNTILAINDRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWY
                     LKE"
     gene            3703..4500
                     /gene="cas5"
                     /locus_tag="KRN00_002162"
     CDS             3703..4500
                     /gene="cas5"
                     /locus_tag="KRN00_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBH1828027.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYIKMGKGKDKEKFLLKGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVKLKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPH
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            4527..6935
                     /gene="cas3"
                     /locus_tag="KRN00_002163"
     CDS             4527..6935
                     /gene="cas3"
                     /locus_tag="KRN00_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
                     /protein_id="HBH1828028.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINNILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISVESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKSTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGVNKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            7377..8324
                     /gene="prmA"
                     /locus_tag="KRN00_002164"
     CDS             7377..8324
                     /gene="prmA"
                     /locus_tag="KRN00_002164"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBH1828029.1"
                     /translation="MNNWIEVTIKTTTEAVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKDFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            8343..9101
                     /locus_tag="KRN00_002165"
     CDS             8343..9101
                     /locus_tag="KRN00_002165"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBH1828030.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            9103..10401
                     /gene="mtaB"
                     /locus_tag="KRN00_002166"
     CDS             9103..10401
                     /gene="mtaB"
                     /locus_tag="KRN00_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBH1828031.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            10444..10794
                     /locus_tag="KRN00_002167"
     CDS             10444..10794
                     /locus_tag="KRN00_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBH1828032.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            10957..11136
                     /locus_tag="KRN00_002168"
     CDS             10957..11136
                     /locus_tag="KRN00_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBH1828033.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            11166..11609
                     /locus_tag="KRN00_002169"
     CDS             11166..11609
                     /locus_tag="KRN00_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBH1828034.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            11720..12217
                     /locus_tag="KRN00_002170"
     CDS             11720..12217
                     /locus_tag="KRN00_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBH1828035.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            12410..12973
                     /gene="raiA"
                     /locus_tag="KRN00_002171"
     CDS             12410..12973
                     /gene="raiA"
                     /locus_tag="KRN00_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBH1828036.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            13186..13422
                     /locus_tag="KRN00_002172"
     CDS             13186..13422
                     /locus_tag="KRN00_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBH1828037.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            13435..14778
                     /gene="yqfD"
                     /locus_tag="KRN00_002173"
     CDS             13435..14778
                     /gene="yqfD"
                     /locus_tag="KRN00_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBH1828038.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKEFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNELYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            14717..15832
                     /locus_tag="KRN00_002174"
     CDS             14717..15832
                     /locus_tag="KRN00_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBH1828039.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            15889..16350
                     /gene="ybeY"
                     /locus_tag="KRN00_002175"
     CDS             15889..16350
                     /gene="ybeY"
                     /locus_tag="KRN00_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBH1828040.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            16356..17075
                     /locus_tag="KRN00_002176"
     CDS             16356..17075
                     /locus_tag="KRN00_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBH1828041.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            17194..17595
                     /locus_tag="KRN00_002177"
     CDS             17194..17595
                     /locus_tag="KRN00_002177"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBH1828042.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            17659..18552
                     /gene="era"
                     /locus_tag="KRN00_002178"
     CDS             17659..18552
                     /gene="era"
                     /locus_tag="KRN00_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBH1828043.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            18564..19943
                     /gene="mgtE"
                     /locus_tag="KRN00_002179"
     CDS             18564..19943
                     /gene="mgtE"
                     /locus_tag="KRN00_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBH1828044.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            20016..20171
                     /locus_tag="KRN00_002180"
     CDS             20016..20171
                     /locus_tag="KRN00_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBH1828045.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            20137..20910
                     /gene="recO"
                     /locus_tag="KRN00_002181"
     CDS             20137..20910
                     /gene="recO"
                     /locus_tag="KRN00_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBH1828046.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            20903..21502
                     /locus_tag="KRN00_002182"
     CDS             20903..21502
                     /locus_tag="KRN00_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBH1828047.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            21662..22540
                     /gene="glyQ"
                     /locus_tag="KRN00_002183"
     CDS             21662..22540
                     /gene="glyQ"
                     /locus_tag="KRN00_002183"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBH1828048.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            22540..24606
                     /locus_tag="KRN00_002184"
     CDS             22540..24606
                     /locus_tag="KRN00_002184"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBH1828049.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQNDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKVLIEHALD
                     NYSELDFDKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKIKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLEICDL
                     SKIVYK"
     gene            complement(24772..26319)
                     /locus_tag="KRN00_002185"
     CDS             complement(24772..26319)
                     /locus_tag="KRN00_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBH1828050.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSTSCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DTFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
BASE COUNT        10790 a         2586 c         4739 g         8251 t
ORIGIN      
        1 ggagtttata aataaggtca tataagttaa attatatcga ttttatttaa ataaccccat
       61 atttattaat tattagaaat atattttagt tattgactga ataataaata ctgtaatata
      121 atggaaatac agtttaataa atataaaaat agaaagaggg aattttaaat gaatttgaag
      181 aaaaaagaga aaatagttaa gcctgtttta aagaagctta cagaaatagt attaaatata
      241 ttatcaaaaa aaatattaaa ctatgctata tatgcaattt ctgttttgat agtaacaaaa
      301 gttgttataa atatagattt gtacatatcc atattgtatt attagatatc ttatagatat
      361 aaaaaattaa tagatatata tctattaatt ttttatatta caaatagaga ataatgaatt
      421 atactagaaa gtaggaggtg aaaatatgag cagaatttca atttttatgg aatcatgtaa
      481 tggcaaattt ccaaatgaaa attcaatgtt gtcagtttcc tttataaaaa atattttaaa
      541 tgcagaaaac aaagattttg ctaaaaacat atttaactat ggggaagaaa gaaaaaacaa
      601 taagcaaata aaggatataa atacagccat ttacatacca aatcttataa gaagcaaaaa
      661 tgagttactt gttgatggag atataatatt caatataagt ttttataatt attctatgtt
      721 cagtaaatta tacaatggaa ttttaaaagt aaaggagcta gaatataaag gttatagatt
      781 taaaataaaa aatataaaaa tacataaaga acacgagata aaagaaaatg gtgttatatt
      841 taaaactatg tctcctataa tagtaaagaa taaagaaggt aaatatttag atgtagaaga
      901 ttcaaattat atagaatgtt taaactatat agctaatcta actctggaga gtataagagg
      961 tagtgggctt agaaagccat tggaatttat acctcttaac ttcaaaaaaa gagtgttaaa
     1021 agaaaagatt cgtggattta aagtgagaga atattactat ataaatgctt atgcaggaac
     1081 atttttttta aaaggaaata tggaagattt aaatgcactg tataaaatgg gaattggata
     1141 tagaaggacg gaaaatgcag gaatggttga tatattaaag tagcgaggtg agagaaataa
     1201 aagctaaatt ttatagatca ggtgatattg taagagatat tggcattgtt tacttttatg
     1261 aattactaat ggatttaaaa aacgaactag aaaaaaatga ttataagcta aaatttactt
     1321 gtgagttaaa tagaaattat ttatctttag aatctgcaga atatatagaa cctaagtata
     1381 tatctgatta tatattagaa aatcaacttt ttaaggtatt taaaaatggg aaaaaggaaa
     1441 ccttagaaaa aatatttagt aatatagata atttaacgta tgtaaatttt attgaagaat
     1501 tagataaatc ttctgcaact gagaaacaaa aggaagggat taaaaaagat tttaaaaaca
     1561 gaagatttcc atatgttaga aatagtggta agtatggatt aaacacgagt ctagaaaata
     1621 tggaaacaaa tgtaaaaagg atagtagata ctgtaattaa atcaaatata gagatagata
     1681 aacttgattt gacacaatat gaagaaaaag atagtgtatg taatgtttgt aatataaata
     1741 aaacaacaaa actagatatt gatttaagag aacgaaagga ttctaagtat aactttttat
     1801 ttagaggtgc agaaaaatca ggctttaaaa taagtggaca agttgaaagt aatatttgtt
     1861 ttgagtgtga atttttcaac ttaatgtgtc ttttatatat aaatttaaaa agaccaatgg
     1921 tttttgcata tacgaatgat ttaagagaat tagcattttt aaatcataag ataatgctta
     1981 aaagaaaaat gtattcagat aaatcatttt ataaaaaact tttgcatgaa aaaataagtt
     2041 caattagact atataggttt gatattgata cgaataaagg tataattcta aagtttgact
     2101 ctattataga gtataaagaa ttattaaaaa aaattgaact tatagatatt atagataatt
     2161 ataatttttc aagagaagca gcaaatacta aaaatttggg taaaaaaatg attgataatg
     2221 ggaatttatc aaatttaaaa gaattattac ttgataatat aagtttttta aagcaatcaa
     2281 ctggaacttc tcgagaaatg gattttgtat ctagctcata taatatcggt ttatatataa
     2341 aattgtgttg gattgtagat ggaggggagg agtataaaat gaaaaactat atggaaagta
     2401 atttaatata ttcaagagta ggtaaagact tatttaataa aatgacagat gaatctagaa
     2461 gaaaaaattt ttctatgaaa gtgattcaac tacttaagtc taatgataga gctcagttat
     2521 ttcaaactat aatgcatgtg ttagtttcta atggaatctt aataggagaa ggctttgtag
     2581 aagggataat gcagagttct gaattagagt taaatacaaa tgtaggtata tttattcaag
     2641 aaatcatgaa ataaaaaagg gggaaaattt aaaatgaatg aaaaaagagt aaaaggagta
     2701 acattaacta tactgacaga aagcccagtt ccactttcgt atgaccaagg gtatggaaat
     2761 tatacaccaa taaaaaaaga acaatataga gaaaaaatac atgcaaaaac tagtatagcc
     2821 acaataacat atgatttaag aagaatgctc caccaagaat atggttggaa tttaagtaat
     2881 attgtttttg ggaaaaaagg aaatatatat ccatctatta agaaaaatgt aggatgtgta
     2941 gatgaaaatg gattagagac tgatgtattt ggttatttga taccacttaa agataaaggt
     3001 tctataagta aagcttctcc gcttagaata atacctttta ggtcattaaa tccatatata
     3061 ggttcaacac agctaataac aaatagaggt tttttaagta gcgaatttgg tagaaaatat
     3121 tatgatgaga aggaagaaaa tgaagtacct agagatgaaa actttccaac aacacaagca
     3181 ttagcaatag aagagacttt atcagattac tacgtttata caataacatt ggagcttgat
     3241 agaataggag tagtagaagt agaagatggg aagttacttt taccagaaga aagaaaattt
     3301 atgagtaagg aattaagaga aaaggcagta aaagatatat tagatgcaat tactgtgttt
     3361 acaagaaaca taaaacattc atcagtacta ttaaaaccac ttgcagtaat gggtggagct
     3421 tttgataaag ttgtaccgtt tttttgggat gatgtagatt ataatgctga tagtggtgag
     3481 ataaatttag agggagttat agaaactata gaaagttata gccttaaaga aagtaataca
     3541 atacttgcta tcaatgacag attaaaaatt tctaataaaa aggaattaaa taagtttaat
     3601 ttaagtaaat accctgtaaa agagattaaa aatctagcag atagattgga aattggagaa
     3661 gataatatgt ggtatttaaa agagtaggag gttttttgaa ttatgaaagt attacaatgt
     3721 aaacttaagc aaccaactgc tcactataga gacccaaaag tatttcaaaa tgaatatata
     3781 agtactttaa atttaccatc taagactaca ataatgggga tgataacgta tttatgtgat
     3841 agaagattaa actctgatat agatatagga ataattggaa cacatcatca tagagaacta
     3901 gaattttcaa gaggagaaaa cattgatttt tggaatgaat atataaaaat gggaaaaggt
     3961 aaagataaag aaaagttttt gcttaaagga aactactatg attactataa agagcataaa
     4021 gctcaaaata gcatattaaa ctatgaagtt cttaaagaag tagaactgac tatatttatt
     4081 tcttgcaagg atgatgaaga acttgaattt attagaaaaa agcttgaaag tccatgtaaa
     4141 tatgcaaatt taggaagaaa agaagatttt gtaataccaa gtgaaaaagg gtgttttgtg
     4201 aaagaagtta agttaaaaga ggttatacct atgaatactc gtgatgctat aaaagaaaat
     4261 ataaaattaa agaatacata tgtaagagtt gacttaagag ataaagagaa tgtcgagact
     4321 ataataaatc aaggtgtatt gattgcattg cctcataaat ataaagattt agaagcaaat
     4381 agagatgata gagtttatga gttttgccat tatatatatg ttgataatga tggtatatat
     4441 cctaaaaata ttaaggtaaa tgtatgtatt gatacaaaag aagtttttac atggctttaa
     4501 attattttga aagataggtg tttatcatga aaaatatcat gcaaaaagaa atattagcta
     4561 agtcatacaa tttaagaact aatcaacaag agcaaacatt agttgaacat attaaggatt
     4621 tatttgaagt attagaatct atattagaat taaatctata ttcagataaa gatgtagaga
     4681 tactaaaaat atgttgtgct ttgcacgatt taggaaaaat taattcaatt atgcaacaaa
     4741 aaatggagat taataataaa atatcgtata gttgctcaga agaagagagg aaaaagttag
     4801 agtctgacaa aaaatcttta aaaaagatag caagacataa tatattttct ggagcatttt
     4861 taaaagatat attagaaaaa atgaacttgt cagaagaaga taagttatat atatataaaa
     4921 gtataatgtt acatcatgga aactatgaag attatatgag gttaagtatt agtaaagttc
     4981 aagaagaaat ttatgagtat attgaaaaag gcattttaga aaaagaagag tttaatctga
     5041 aagatataga aagttatata aataacattt taaatgtaga ctttaaattt ggtgaagatg
     5101 tattggatta tgattacata gataaattaa gtgaaagtat gtttatagac agtgattata
     5161 acaatggtca aatagatgat tcagttttaa attatagaaa gtttaagtat attttatata
     5221 aagggatgct gaacttaata gaccatagtg catcaagtag acagaaaggt ataaaatttt
     5281 ataacgattt tactgatgaa gaaattgata atatgatttt aaatgagata tataagagtc
     5341 agggtaattt agaaaaaaat aatatagagt tcaatactat acaaaaaagg ttgagagaac
     5401 tttctggaag aaatgttctg actgttgcat ttacaggttc aggaaaaaca gctgcagatt
     5461 atagaaagac ttttaaaaga aaattctttt tagtgccaaa taaaatatca gtagaaagtt
     5521 tttatagaaa aaatattttt caaaataaaa atgatttaga tacaagaagt agtaatgatt
     5581 acattggatt acttcatgga gatataaact tatattcaga gaatgaagat aatggagaac
     5641 atgattttgt attgacatta agggatatag atttgagtat aaacttttgt aaaccttgtg
     5701 taattgcaac agttgatcag ttattactta gtatgtttaa atttccggga tatgaaaaaa
     5761 tattcgcagc cgtaaaaaat gcatctataa ctgttgatga agtacattta ttggaaccaa
     5821 agatgttttt gattttgata tattttatgc agtttgcatg caagtactta gatgttgatt
     5881 ttcacttaat gacagctaca cttccaaaat catataaaga gcaaatgata aacaagggaa
     5941 ttatttttca agaagaaagt aatgaaaatg ttactgataa aggagaaata gtttttattg
     6001 agagcaacaa ggaagaagag atttgtgaag gtaaagatgt aaaggtttct tttataaagg
     6061 aaaaagaaat caagtcaata gttgaagatg ctttagaaaa taaacaaaaa attcttataa
     6121 taaagaatac tattgattca gtcaatagaa catatgagtt tttaaaagaa aatttatctg
     6181 ataagtatgg tggtgtagat atagatgttt tacatagtag atttaagttc aaagataaaa
     6241 aagagaaata tagtaaaata ttaaatggag agggtgatat ttggatatca actcaatcag
     6301 tagaaatatc cttggatttg gatttcaata taataataag tgatttagca actatggata
     6361 gcttaataca aagaatgggt agatgcaata gaaataataa gtatgaatat ggaaactttt
     6421 atattctacc tagtgaagat aaaatttatg acaacaaact taagagcaca actaaaaaca
     6481 tcttaaagga catattaaaa actaactcta tttttacaat gggaattaga aaaactattt
     6541 tggatgatta ctatgataat agtgtagtca aaaaatattt tgaagagaat tttataagtt
     6601 gtgataaaga aattaagaat atttatggtg taaataaaga aatttttgat ggattggatt
     6661 taatttttaa ttttgaacct tacaaaaata ttgttgatag taagaaggaa gcagctaaaa
     6721 tttttagaga tgttgatgtt agttacaaaa ttattctgga agaagatttt tataaggaag
     6781 atagagagtt acaacaagat tcgattcaag tatcagggtt tatatttaat agattatatt
     6841 attatgggtt aataagcaaa gtagaaggat acatggtact aaaatctagt agtaagtttg
     6901 agtataatag tactgtaggc ttaattttga agtgagcata tgtttaaata taatatacct
     6961 ttagacattg aaaatacaaa aagtactact gtaagctcac tgtaaaaact atttttttaa
     7021 aaggaaaaat aagttgtgag atagagtgtt tacaagtgta tatagataat aaatttgagg
     7081 tttaagatta actaagtggg tttcaggtac atcgcgaaaa taattataag ttggagattt
     7141 tgtatgttta agattaacta agtggatttc aaatattgat atagtagata taatagaagt
     7201 tttattatta ggtttaaaat taactaatcg gatttttaaa tattctgact attatataag
     7261 gatattatta gcttgaattt aaaaccaata atataaaaca acaaaatatt atatttatga
     7321 tataataaaa gttatggaaa aacaggaata ttactataga gaagagaggt aaacttatga
     7381 ataattggat agaagtaact ataaaaacaa caacagaagc agttgaacct ataacgaata
     7441 tactatatga acaaggagct ggaggagctg taatagaaga cccaaaagac tttttattcc
     7501 aaaagaaaaa tgaactagac tgggattatg ttgaagaaga agtatttaaa aagaatgaag
     7561 aagatgatgt tcttataaaa acttatgttt ctgaagaaaa aaatgtgatg gaatttgtcg
     7621 aaataataaa gcaaaaagtt ttagggttaa aagattttgg tatagatata ggtgaaggaa
     7681 gtgtatcatt ggaccaagta aatgaagctg attgggcaaa tgcatggaaa gcatactaca
     7741 aaccaacaaa agtaggacaa agggtagtag taaagcctac atgggaagat tatgctatgc
     7801 aagaggggga tttaatcata gagcttgacc ctggaatggc atttggtaca ggtacacatg
     7861 agactactag tatgtgcatt agagaattag aaaagtacgt gaataaagat tctaaagtat
     7921 ttgatattgg ctgtggtagt ggaatccttg caatagcagc agctaaatta ggagcaaaag
     7981 aagttgtagc tgtagattta gatgaagtgg ctgtaaaagt tgcaaaagaa aatgttcttg
     8041 aaaataaagt tgaaaaaagt gtatctgtaa tgcatggtaa tttaactgat gtaataaaag
     8101 ataaagcgga tgtaatagtt gcaaatataa tagctgatat aataaagata cttgcaaaag
     8161 atgttcaaaa ctttatgaaa gaagatgcta tattcatatc ttcaggtata attttggata
     8221 aagtagaaga agttaaagaa agcttaattg aaaatggatt tgaaatagtt gaagttcaaa
     8281 aattaggtga atggtcagca atagtttcta agcttaaaaa ataagggata tggtgacgta
     8341 taatggatag attttttgtt gaaaaaaata atataaatct acaagataaa acttgcacta
     8401 tagaaggtga agatgtaaaa catatttcaa aagttttaag atgcaaatta ggtgagaaac
     8461 ttgaaatatg tgacaagaat aataatgagt atatttgtga gataatgaat atagataaga
     8521 gtatagttaa tttagaaatt ttagaaaaag ttgatataaa tagagaatca gaacttaaag
     8581 taaggctata ccagggactt ccaaaagctc caaaaatgga aatgatactt caaaaattaa
     8641 ctgaagtggg tgtagaagaa ataatattag ttcaaactaa gagaagtgtt gttaaagttg
     8701 atgacaaaaa agaagataaa aaatttgaac gttgggaaag aataatttat gaagcagcaa
     8761 agcaaagcaa aagaggtaag ataccaaaat taagaggtgt tttaagtttt aaagaagctt
     8821 tagaagatat gaaaaaaaat aatgtaaata tttgccctta tgaaaatgaa agaacagttt
     8881 caataaaaca tgcactaaaa aaatgtgatt ctaatataga tagtgttgga atttttatag
     8941 gtccagaagg tggattttct gaagaagaaa tagaacaaat acaaaaaaat aattgtaatg
     9001 ttgtatcatt ggggcctaga atattaagaa ctgagacagc ttctgttgta gcatcaacaa
     9061 tagctttgta tgaactaagt gatttaggag gagaaaaata aattgaaaaa agtagctttt
     9121 tatacacttg ggtgtaaagt taatcaatat gaaacagaag ctatgctaga actatttgag
     9181 aaagatggtt atgaacaagt caatagtgaa gagtatgctg atgtttatgt tataaataca
     9241 tgtacagtta ctcatatgag tgatagaaaa tctcgtcaat atataagacg agttaaaaag
     9301 aagaatccag atgcgataat agccgttgta ggatgttatt ctcaggtatc tccggaagaa
     9361 attttggata tagaagaagt aaatttagtc atgggtacaa atgatagaag aaagattgtt
     9421 gaagaaatta aaaagataaa ttcaagtaag aaagttagta cagttgacga cataatgaaa
     9481 gttaaagctt ttgaagaaat agaaatcagc caaactaatg gaaagactag agcatttatg
     9541 aaaatacaag atggatgtga cagattttgt acttattgta tcattcctta tgcccgagga
     9601 cgcgttagaa gtagagatat tgatagtata gtcgatgaag tgaaaaaatt ggctaataat
     9661 ggctataaag aggttgtatt aacaggaata catgttgcct cttatggaaa agatttaaag
     9721 gatagggata ttaaacttct tgatgtaata aaacaaataa accagataga aaaaatagaa
     9781 agaattaggc ttagttctgt tgaaccaatt ttatttacag atgaatttgt aaatgaagtt
     9841 ttaaagatgg ataaagtttg tcctcattac catttatcac ttcaaagtgg atgtgatgaa
     9901 actctaaaaa gaatgaatag acgatacaca actttagagt acaaaactat tgtagataga
     9961 ttgagaagta aaatgccaga tgtggcaata actacagatg taatagtagg ttttcctgga
    10021 gagacaaatg aagagtttaa aaaaacgtac gagtttttaa aagaaataga gctttcacaa
    10081 atgcatattt ttaaatattc accaagaaaa ggaactccag ctgcaactat ggaaaatcaa
    10141 gttgaccctc aaatgaaaca ctttagaagt gaacaacttt taaatttaag taaagtaaat
    10201 tttaataaat ttgcaactaa atttatcggc cgtgagctgg atgttttgtt tgaacaaaat
    10261 atagaaggca ataaatatga gggattaact tcaaattata taagagttgt tgttgaaagt
    10321 gacaaaaata tacaaggtca gatattaaaa gtgaaaataa atgatgtaaa agatgaatat
    10381 gtagaaggaa ttttgctata acatgtagaa attataatat ttataagata ggaggtggaa
    10441 agaatggatt gtattttttg taaaatagcg aacggagaaa taccttcaac taaagtttat
    10501 gaagatgata gagtcttagc ttttaatgac ttgaacccag ttgctccata tcatatatta
    10561 gttgtaccta aaaaacatta tgatagttta attgatattc ctgataaaga gatggacatt
    10621 gtgtcacata ttcatgttgt tattaataaa atagctaaag agaaaggttt tgaccaaact
    10681 ggattcagag tcataaataa ttgtggaagt gatggagggc aagaagttaa acatttgcac
    10741 tatcatattt tagctggtaa aaagcttcct aattacgaag cgggacaaaa ctaaactaaa
    10801 ttattgaaaa attgagttcc ttcttgataa aaatacttga taaaagtaaa aatttagttt
    10861 ataataaaca aagtgttagg ttgtaatgca tattatgcaa aaagaacata gttacagtcc
    10921 cagcataatt gcgctattgg agggagggaa aaagaaatgt cagaagtaag agttagagag
    10981 aatgaaacat tagacagcgc tttaagaaga ttcaagcgtc aatgtgcaat gtctggcatc
    11041 atgtcagaag tgagaaaaag agagcactat gataagccaa gcgttaagcg taagaaaaaa
    11101 gctgaagcag caagaagaaa aaacgctaag aaatagtagt aaataagaat aaagaggtga
    11161 aggggatgtc ccttaagcaa aagttacaag aggatttgaa atcttcgatg aaaaacaaag
    11221 atacagtgag aaaatctgta gtaactttaa taagagcttc tataaagcag tatgaggttg
    11281 ataatagggt cgagcttgat gaagatggaa ttatcgatgt aatagcaaaa caattaaagc
    11341 aacgtagaga tgcattagtt gaatttgaaa aagctggaag agaagactta ataaaagaaa
    11401 cagaaggtga aattgaagtt ttaaaagagt acctacctca acaattaagc gaagaagagt
    11461 tagaagaaat tgtaaaatct actatatctg aagtaggggc aacttctatg aaggatatgg
    11521 gaaaaataat gtcagttatc caaccaaaag ttaaaggaag agctgacgga aaacttataa
    11581 ataagttggt aaaacaaaac ttacaataga ttgatatagc ctagagagaa atctctaggc
    11641 tttttatagt ttttgggaat aacgagtcat atttgagcat atctataatc aaagaaaatt
    11701 ttgaaagaag gggaaaaatt tgattatatc agtaaaagag attaggaatt ttttgataaa
    11761 catatttata ccactaataa taggttactt aagtagcatc ttaacaatga ttatcagtgg
    11821 aacagatatt tcaacctatt atttacaact cacaaagcca agctttgcac caccagcttt
    11881 tatctttcct atagtttgga ctatattgta catattgatg ggtatatctt catacctaat
    11941 attaagaaag ggttacaact tacctaaagt aagagatgca attttttatt atggattaca
    12001 acttgtatta aactttattt ggagtatact attttttgga tttggactta gatttacagc
    12061 tttgatagat ataataataa tgattttggt ttctataata atgatttcga agttttctaa
    12121 aatagataag agatctggat acataaattt gatttattta atgtggcttg tttatgcagg
    12181 atttttgaac tattttatat ggtttattaa taaatagaat gtaaagattt tgtaaattac
    12241 cctgtacttt taataatatc ataacaaacg aaaaataaat agactattaa aaataatcat
    12301 tttcatatac aataatatta atttaaatac aataaattta taaaaattgt atttaaagat
    12361 taacatatta aagtattaga attggaaagg cttgaaggga gaggttttta tgcaaataat
    12421 agtatctggg agacaaatga aattaactga cggaataaaa ggatacgtag atggaaaatt
    12481 aagtaggtta gaaaaatacc ttgatcctga atcagaagtg aaagtaacag taagtgcgaa
    12541 aaaggataga caaaaagtgg aggttacaat aattcctatt aacggtcaaa taataagagc
    12601 agaagacgta gaagatgact tatatgcagc aattgatatt gtttgtgaca aattaagtag
    12661 acaagttgtc aaatataaaa ctaaagttaa agacaaagtt caaaataata agagcataag
    12721 atttgaaaat cttgacttta tagataatag cagtgaattt gatgattatg attatgatga
    12781 tgaagaagat gagaatatag taatagaaag aagaaagaaa tttaatgtaa aacctatgag
    12841 ttctgaggag gcgatacttc aaatggaact agtaggacac aatttctata tgtttagaaa
    12901 ccaagataat tttgaaataa acatagtgta taagcgtaaa gctggtggat atggtttaat
    12961 agaacaagat taataaaaat tgtatacgtt tagattttat ataagaaaaa ataaaaaggt
    13021 aatcatgttg attttttatc aatatgatta cctttttctt gtttaaataa tatattagat
    13081 attaggtatt tattatataa aaattttaaa actaatctgt tacaacatca ataaagtgca
    13141 taaataccta tttcaagcat aaaattaatt aagggggtaa tgcttatgtt agaaatatcc
    13201 actgatttac aagtaaatca accagttatt actgttacaa gtaatacgtt tattagtata
    13261 gaaaattatc tatcaatatt agaatatgaa gttgatttaa taagaataaa gactaaagtt
    13321 aaaacaatta aaatatctgg ggataaactt tcacttaagt atattactga tagtgagata
    13381 ggtataaaag ggattatcta caatgttgag tatgttgatt aggaggagat acacttgata
    13441 agttttataa ggggatacta tgttatagtt gtggaaggag taggactcga acaattttta
    13501 aatcatctta taagaaatgg gataagtgtt tacaatgtaa ctagaataaa aaatactaaa
    13561 atggagtttc atatagatag acaagatata aaagaattta agaatgttta tagaggaagt
    13621 aagtttgata taaaggtaaa gcaaaaaact ggggtccctt ttattatcaa aagagtttat
    13681 aagcacaaag gtatgtggat ttgtgctctt gtttctttat ttttattgat gtctacatca
    13741 cagtttgtga cagatgtata tatacaatct cctgaaggta taaaaaaaga agctcttaga
    13801 aatgagcttt ataaggttgg agtaagacca ggagtctata agaagagtat tgatagaaaa
    13861 gaagttagag accatatgat gtcaaaattt aatgatgtgg catatttatc tatcaatgta
    13921 aaaggaacaa atatatttgt tactgttaca aaaaaggcag aatccctaaa atctacagac
    13981 caatcaaatt attgtaatgt aattgcttta aaaaatggta taatagaaaa ggtaatccct
    14041 agaagtggta aatcagttat taaatctgga gacatagtcc aaaagggaga tgtcttatta
    14101 aatggagcta ataccaagtc aataccagaa gtatgggcaa gtacttttta tgagtccaca
    14161 aaaaaggcaa gttatgtaga tactgtaaat aaaaaaactg gagaaaagaa aaatatatat
    14221 acactaagtt tttatgataa agagtttaca atgagaaaaa atataaaata taaagattat
    14281 gttgttgaaa ataaagaaaa aaaactatca ataggaaact atacttttcc aataaagata
    14341 aaaacgagta ctttttatga aacaaaaaag gttgaagtaa aaaggaataa agaagagtta
    14401 aaaaaagaat tatctgaaaa agctttaaaa gagttagaat acataatccc agcttcggct
    14461 agaataatag atgtaaaaca taactttaag gttaataaaa atatgttaga atatttaata
    14521 acagttcaaa ctagtgaaaa tattgctaaa atttatcctc ttagtaagtc agaagcagaa
    14581 aggtttataa aggaagaaag taaaccagat gaaggtgaag aggaagttcc ttccaatcca
    14641 gaaaaaagac cattaaatga tataagaaat gagtttgatg aggataataa ggataataaa
    14701 gatcaaaaca attctgatga aaataatagt aatcaaaata gtaataatag tcaaaataat
    14761 aatagcaata acaactaata aaattaaact taaaatctta ggaggactaa ttcaattgat
    14821 aatacaaaag aaatttacaa tagcagatgg taactttgaa agagagttat ttggcaactt
    14881 tgatgaaaat gtaaaattaa tagagaagac tttaaatata gatgtaatac ttagagaagg
    14941 caatataatt ttaattggag aagaaaaaaa tgtagattct gcattaaaac ttatgaatga
    15001 attacaccaa actgtatcaa atggtaagca tttagataag cagagtattt cttattcatt
    15061 atctcttttg cttgaaggaa gtgaacaaaa aataaaagaa cttgagggga caatcgtcat
    15121 aactcaaagg ggaaaagctg ttcaacctaa aactttaggt caaaaagaat atataaaact
    15181 tatagaaaat aatgatataa cttttggtgt tggacctgct ggaacaggaa agacttatct
    15241 tgcggttgct atggcagtaa aagcttttaa aagagatgaa gttagtagaa ttatacttac
    15301 aagaccagct gtggaagcag gagagagtct aggtttttta ccaggagatt taaaggacaa
    15361 agttgaccca tatttaagac cactatatga tgccttattt gaaatgttgg gtgctgataa
    15421 atttaataag tatttagaaa gaggtactat tgaggttgca ccacttgcat ttatgagagg
    15481 tagaacactt gataattcat ttataatatt ggatgaagct caaaatacta cttctgaaca
    15541 aatgaaaatg tttttaacta gacttggatt tggctctaaa gctgtagtta caggagatgt
    15601 aactcaaaca gatttaccac aaaataagaa gagtggtcta atacaagcta cagagattct
    15661 taaaggtgtt ccaggtattg ggtctataat gctaacagat agagatgttg taagacatga
    15721 gttggtacaa agaataataa gagcttatga gaagcacgac aaaagagaag aatttaaaaa
    15781 agaagaacgt aaaaaagcga aaatgcagga aaagactttc aaaagaaagt aaaagtgtag
    15841 taatatagat atatagcatt attaatgaat aaaaagtagg tgtagtgaat ggatttgata
    15901 ctagatgata gacaagataa attagaagta agtgaggagt taattgaaaa gataaaggat
    15961 ataatcatag aatgtttaga ttatgaagga tatgatgata attatgaagt gagtctttct
    16021 tttgtagata ataaagagat tcatgaatta aatagagaat atagaggagt tgatagagtg
    16081 actgatgttt tatcatttcc tcttttaagt gatgattttg aggatgttga gttagaagaa
    16141 gaatccctag gtgacatagt agtatctctt gaaagagcct tagaacagag tatagagtat
    16201 aaccatagct ttgaaagaga agtatgtttt ttaatatgtc atagtatgtt tcatctttta
    16261 ggttatgacc acgatacaga tgaaaataca aaagaaatga gagaaaaaga agaacacata
    16321 ttaaataagt taaacataac aagggagtag tttttatgaa accagaaaaa actcgtcaag
    16381 gtataattaa agcatttaat gcagctatag aagggatatt gtatacattt aaatttgaaa
    16441 gaaatatgaa aatacattat ttaggttcag ttgctgttct tataataagt ttgtttttta
    16501 acttttcaaa attagaaatg ataatgttac ttatgtccat atgcttagtt gtagttgctg
    16561 aaatgtttaa tacagctata gaaaaagctg ttgatttagt aactgatgaa tatcatgttc
    16621 ttgctaagat agcaaaagat gttgcagctg gaggcgttct agtggcagca ctaaattcag
    16681 tagtagttgg atatattttg ttttatgata aattgacaga tatatctgga atattaattt
    16741 ataaaataag agaatcagaa ttacatataa ccttgatatg tatattattg gttcttatag
    16801 ctgttgtagt tgtaaaagca ttgacttcta caggtactcc tctaaaagga ggaatgccaa
    16861 gtggtcatgc tgccttagca tttgctatag caactgcaat tacacttatg actgaaagag
    16921 ttgttgcctc tactcttgca tatataatgg ctgtattagt tgcccaaagt agaattgaag
    16981 gaaaaataca taccttttgg gagactattg ctggagcttt gttaggtgtg ttgatagcta
    17041 tattagtatt tcagcttgga atgttctata attaaaataa atgtacataa aatatttaaa
    17101 ataaaacaaa tctgtgctaa ttaaattttt atgatataat gtagagtatt aaataaaaat
    17161 aacttttaat tattgtatac aggaggagtt gttgtggata acatagaatt gttaaggttg
    17221 gcagaagatg ccagacaaca ttcttatgct ccttactcag gttttagagt aggtgcagct
    17281 cttttaacta agagtggtaa agtttatact ggatgtaata tagaatgtgc atcattaggt
    17341 ggaacaaatt gtgcagaaag aacagctatt tttaaagcaa tatcagaggg tgataaggat
    17401 atctataaaa tagctatagc aagtgataac tcagaaaata atgagcaaac atatccatgt
    17461 ggaatatgca ggcaggtaat tatagagttt ggttctgata taaaaataat aacgggatat
    17521 actaaaggag aggtgtttga gcatagtata aaggatttgt tgccaaacta tttctctgga
    17581 aatgatttaa aataaattta aaagtataaa taaatttaag taattaaaac aagaagataa
    17641 aaagttagga gacagttaat gttcaaatca ggttttgtca gtatagtggg tagaccaaat
    17701 gtaggaaaat ctactttaat gaataatgta gttggagaaa aaatagctat aatgagtgat
    17761 aagcctcaaa ctacaagaaa tacaatacaa gcagtatata cagatgaaga aatgcagata
    17821 gtattcttag atacaccagg tattcacaaa ccaaaaaata aattaggtga atttatggta
    17881 aaggcagcaa cagaagcttt taaaaatgta gatttaatat tatttgtagt tgatgattct
    17941 aaaaaaatag gtcctggaga tagaaagata atagaggatt taagaagtgt taagacacca
    18001 ataattttag ttgtaaacaa aatagaccaa ctagaccaaa aagatgagct atttgatata
    18061 atcaaaatgt atgatagaga aggcattttt aaagaaatag taccaatatc agcattaaaa
    18121 ggaaagaata cggatacctt aataaaagtt atacaaaatt atttagaaga agggccaaag
    18181 tattttccag attatatgat tacagaccag ccagaaagag tattaatagc agaacttata
    18241 agagaaaaag ttcttcacta tcttaatgat gaaatacctc atggtgtagc tgttgaaatt
    18301 gaaaaaatga aagcgagaaa tgataaggaa atagtagatg tatctgctgt aatatactgt
    18361 gaaagagatt cacataaggg aataataata ggaaaaaatg gtaggaaact aaaaggaata
    18421 ggtaagtcag caagacaaga tatagaattg cttttaggtt cacaaataaa tcttcaatta
    18481 tgggttaaag tcaaagaaaa ttggagaaat ttacaaaatt atataaataa ttttggatat
    18541 aatgataaat aaaggtgggt tatatggata ggaaactgga tgcttcccaa gatttattat
    18601 atgaagtaaa atcattaatt gataataata aagtattgga gttaagagaa ttaatagagg
    18661 aatatcatat aattgatata ttcgatataa tggaaaattt agaggaagac atgaaaattc
    18721 aattatttga agtacttcct ttagatatgg catcttctat attagaagaa ggtagtgtag
    18781 agttttttat tagtatttta tctaaactgg atgtagaaca ctcgaaaaat atacttgaac
    18841 ttatgtctct tggagatatg gcagacaagt tgagtgaact tgaagaagaa gaaagagaac
    18901 acataataaa tcttttgaat caagagaatg ccgattatgt aaaagagtta ctattctatg
    18961 atgaagattc tgctggtgga acaatgacca ctggatatat ttctataaat aaagatatga
    19021 cagctcttga ggctatagac catatgagag aagaagctga agaagctgaa actatttatt
    19081 atatatatgt ggttgatgat gaagaaaaac tagttggagt attgtcatta agagaattaa
    19141 taatagctag agacgcaaat atagtagaag atttgatgag tgaaaatata atctctgttt
    19201 atgtagatga agatagagaa gaagcagtaa gattagtatc taaatacaat ttaatagcaa
    19261 ttccagtagt agacagacaa gaaaaattaa aaggaataat aacagtagat gatataattg
    19321 atgtaatgga agaagaagca actgaagata tgtataaatt tgcaggaagt tcagaacatg
    19381 aaagagaagt tgctgaaaaa gaaaacccta cattgagaga gcaaataata tcagcactta
    19441 gaggacgatt accttggtta attattacct tagttggagg gttgttggct tcgttaatac
    19501 tttctaactt agactatata atgaatcctg tatatgctcc attagtattt tttatacctg
    19561 tagtaattgg tatgggtgga aatattggaa ctcaatcatc atctgttaca gtaataacat
    19621 tatctaataa ggatttaaat tttagcaatg tggttagaga aggtattgta ggtattatta
    19681 caggtctttt gtgtagtata ataacaggta ttgtaattta ctttgttatg agaaagttag
    19741 acattgtatt aattgtttca atatcattat ttataaatat ggttttaggt gcaacaatag
    19801 gtgcgtttat gcctgtttta ttaaaaaaaa tggatgcaga cccatctaca gtttcatcac
    19861 caattatatc tacagctctt gatataactg gtatagcagt ttactttata ataacaacgg
    19921 cattattgtc aaaaattgtt taataacttt atgtatgatt tatcctcttc ttactaaaaa
    19981 tataagtata aatgtaagaa gggggttttt taaaaatgaa caatatcagt tgggaagttt
    20041 ttaaaaaaac aggtagtata gatgcatatt tatatttctg tgattgcaaa aacatacatg
    20101 aagaaattga agaagtaagg gagaaaaaag aagacgatga taatcctgaa cacccagggg
    20161 atagtactta aagctataag gtataaggaa agtgatataa tacttacact atttacaaga
    20221 aagcttggaa aagtatctgc aatagcaaaa ggagctaaaa aaaataagag ctctttgctt
    20281 tcatcatcac agttattttc ttatagcaat tttaccttaa aaaaacaagg taatatgtac
    20341 aaggttactc aaagtgaaat aataaaaagt ttttataata tatcctatga tatagaggca
    20401 ttttcttatg ctacatatat tacaaaatta gttgaaaatt ctatacttga aaatcagact
    20461 aataataggc tatttatatt acttgcgcag actctgtatt tgtatacaca ggataataca
    20521 gacaataggt ttataacagc agcattcgag ttaaaatttt tagactatat aggatttaaa
    20581 cctatagtaa ataaatgcat taattgtgaa tgtaaaattt tacaaaattc tgtgtttaat
    20641 atctacgaag gtggtatact atgtagtaag tgtagtaaac tttttgataa taatataaaa
    20701 ttagacttaa caactataag tcttatggaa tatgtattaa gaaatgatat tttaacatgt
    20761 agtaaagcta aagtatcaaa atatataaca catgaacttg agaatattct agacaagtat
    20821 ttgaaagttt atgttgataa tattaatttt aaatcattac acgtattgca aagtgtaaaa
    20881 aataataagg gagtggataa tgatgagtag taatataact attgaaatgg ttgattcagt
    20941 ctttgaaaga gttccaggag caacttatgc agaagcaaaa gaagcattag taatgtgcaa
    21001 tggagatgta attgaggcag taatatattt agaaaataaa aaaaatactt gtaattgtaa
    21061 agcaaaatct gctaaagaaa ctatggaaga agtatttggc aaagatggag aaaatataaa
    21121 gtttcaatta aaagagcttc ttagaaaaag tagtgtagtg agaataatag ttgaaaaaga
    21181 tggaaaaact atgatgaata ttcctttaac agttggagtt gttggattag cttttgtacc
    21241 attagctact ttagttggat tatcagctgc tgttataagt aaatatcgta taaaagttca
    21301 aaatgaagaa gatggagaaa ttgtagattt aggtgaattg aatgaagaaa aacttcacgt
    21361 tttgaagaat atgataacta atgcagcaaa agatgtgaag gatgtagtag ttgacaaaaa
    21421 agaagatgac aaagatgtaa ctgctgacct tatgaaagaa gaatctgaaa agaataaaga
    21481 agacgaagac gaaaataaat agatataaag tgacttttaa aaaatgaaga gaagataatt
    21541 ataagaatta tcactaacat tgacaaattt tatagaattt gatattctaa aagttgtaga
    21601 agaactatta aaatagcctt tcgtgtagac gagaggcttt attgttatag gagggatttt
    21661 tatgaatttt caagagatga tactggcgtt gcaaaaatac tggtcaaagc aaggttgtat
    21721 catgatgcag ccttatgata ttgaaaaagg tgcaggaact atgaatccta atactttttt
    21781 aagatcatta ggacctgagc cttggcaagt atgctatgta gagccttcaa gaagaccagc
    21841 agatggaaga tatggtgaaa acccaaacag actatatcaa catcatcaat tccaagttat
    21901 actaaaacct tctccagata atatacaaga attatatttg gaaagtttaa aagagattgg
    21961 aattgaccca agtgagcatg acataagatt tgttgaagat aactgggaag ctgctacagt
    22021 tggtgcttgg ggacttggat gggaagtttg gctagatggt atggaaataa ctcaatttac
    22081 gtattttcaa caagtaggta atattgaatg tgagcttgag acaggagaaa ttacatatgg
    22141 attagaaaga ttagctatgt acattcaaga agttgatagt gtttatgatt taaaatggaa
    22201 tgataaaata acttatggtg aagtatttaa taaagctgag tatgaaaact caatgtacgc
    22261 atttgaatta tgtgatgcag atatgttgtt taatctgttt gatatatatg aaaaagaagc
    22321 attaagactt atggaaaatg gccttgtaat accttcatat gactatgtgt taaaatgctc
    22381 tcatgcattt aatacattgg atgcaagagg tgcaatagga gttagtcaaa gagcttcatt
    22441 tataggtaga gttagaaata tggcaaagac tgttgcagaa acttttgtaa aacaaagaga
    22501 agaaatggga ttccctcttt taaaggacgg tgacaaataa tgaaaaatta tcttttattt
    22561 gaaatcggtg ttgaagaaat gccatcaaga tttgtaggca gtacactaga acaattaaaa
    22621 aacaatctta gtaaattatt tgatgaaaat agaatagctt ttgataaaat aaatgcgtat
    22681 gggacaccaa gaagacttac tttagtagtc gaaggattga gtgatagaca aaatgattta
    22741 gaagaggaaa taaagggtcc tgctaagaaa attgctgttg atgcagaaaa taatttaaca
    22801 aaaccagcat taggatttat aaaaagcaaa ggattaagcg aatctgacat atattttaaa
    22861 caagttggaa aagaagaata tatatttgcg actataaagc aagatggaaa agaaacttca
    22921 gaagtactaa aagacatatt accagagact ataaaatctg tagtattccc aaaagctatg
    22981 cgttggggag gaaaaaatct taaatttgca agacctataa gatggatagt tgcattgtta
    23041 aatgataaag tattagagtt tgatttagaa ggaataatat cttctaatgt aacaaaaggt
    23101 catagatttt taggtgaaag tacaatagaa gttgattcta tagaagatta ttttgaaaaa
    23161 ttagaaaaaa attatatagt tttagaccaa aacaagagaa aagaaatgat aagaaaacaa
    23221 tgtatagaag tagcaaattc tttaggtgga gaagttgaat ttgatgaaga tttacttgaa
    23281 gaggtaactt atttagttga atatccaact gctttttatg gagaatttga tgtggattat
    23341 ataaaactac caaaagaagt tgttataact cctatgaaac aacatcaaag atattttcca
    23401 gtacttaaag aaggaaaact gttacctaac tttatagctg ttagaaatgg tgattcttac
    23461 agaatagaca atgttaaagc tggaaatgaa aaagttttag aagcaagact tgcagatgct
    23521 ttatttttct atagagaaga tactaagaga aacttagaaa gctacataga aaaattaaaa
    23581 actgttgtat tccaagtaaa actaggaact atttacgaca aaactttaag acttgaaaaa
    23641 ttaagtgctg atatacttga tagtttaggt ttagtagatg aaaaggcaga tactataagg
    23701 gctgctaaat tatctaaggc agatttagtt actggaatgg taggagaatt tgatgaatta
    23761 caaggtttta tgggaaaaga atacgcaaaa gttggaggag agaatgatgt tgtaagtgaa
    23821 gctatttttg aacattatct tccaagattt gcaggagata tacttcctaa gactaatgca
    23881 ggagttgcct tatcaatagc tgataagttg gattcaatag caggtttctt tgctatagga
    23941 atacaaccaa caggttctca agacccatat gctttaagaa gacaagcttt aggtatactt
    24001 agtatactta tggacagaaa agttgctgtg gatataaaag tacttattga acatgcttta
    24061 gacaattatt ctgaattaga ttttgataaa gaagaagttg ttgagcaaat aatgaatttc
    24121 ttcaatgaga gagtaaaaaa tctatttaaa gatttaggaa taagatatga tgttgttgat
    24181 gctgttttaa gttctgatat aaatgatgtt tctgatatgc atatgagagc tttagagctt
    24241 aataattggc tagaaaaaga tgaattagtg gagatgctta ctgcatttaa tagagtttct
    24301 actctagctc aaaaagcaga aagtgataaa attgatgaat ctttattaaa agaagatgct
    24361 gaaattaaac tttacaatga atttaaacaa gtaaagataa aagttaatga attattaaag
    24421 gataagaaat atggtattgc tttagatgaa tttgcatctt taagaccagt agttgataat
    24481 ttatttgata cagttatggt tatggataat gatgaagcta ttaagaacaa tagacttgct
    24541 ttacttaaac aagtatatga tactatgcta gaaatttgtg atttatctaa aattgtttat
    24601 aaataaaatt taaactattt ataagaaata aggctgtctc aaaatagaga tagtcttatt
    24661 tttcattgtt gagatgatga aaatatattt gatttcatag aaaaagagtg tctcataaac
    24721 taaaaagttc attttgagac acccatgttt tttgtaagta aatataataa actatatttt
    24781 atacttatca gttattttgt ttaaaatatt atcatttgaa tttacccatt cataaaaatt
    24841 gcctgatgat gcgtccgata ttttataaag catttcagga atatcactag ctttaaaatc
    24901 tccaagtgat tttcccaatc tagtcttacc tatttcaaaa ctgcctccaa caaataattc
    24961 aaatgtatct gtagatatac catcaacatt cttcttttta ccacataaac ctatgctacc
    25021 aacttgatga acaccacatg aatttaaaca tcctgatata tataacttag gtgctttatt
    25081 taaaatttct tcattatttt gtaatctaaa ataatctatg atttcatgta acattttctg
    25141 actattttgt atgcccattt gacaaattgg aacacctatg caagatgtac tttgttctaa
    25201 ttgagaatta caactaatag ttttacttat ttctaatatt ctttttgctt catttccatt
    25261 taaatttaaa atatataatc cctctgtcat tcctagtcta atcataggat tttcaacatt
    25321 atctaattct ttaagtaaag tacttaaatc ctttgttaac aaaatacctc caactggatg
    25381 tatatataca gtgtataaac catcctgttt ttgaggtatt agtctagaat cttgtatatc
    25441 tattttaact ccaggtttag agtaatctat ttcttcaata ttgagttcaa gactaccatt
    25501 ttctttttct aatttatagt attctttaaa tttttctaaa aatagttctt caccaagtga
    25561 ttcgaccata tatctaaccc tagctctgtt tttattttca taatttccat aatccataaa
    25621 gaatttaatc ataccttcaa cacaatataa ggcatctttc ggctttataa gttcatcaag
    25681 ttctaaagca actttgggtt gtttacctag acctccacct aagaaaactc taaaatatgg
    25741 ttcatcattt ttcaaagtag caacaaatcc taagtcttgt atactacaat gagcagtatc
    25801 tgtgtaacaa ttagaataag aaacttttaa ttttctaggt aaatggtatg tagtagcatt
    25861 tttgataaaa tatttatcag tagcaactgc atatggagta acatcaaaga cttcactagg
    25921 gtcaactcca gataatggag ataatccgac atttctagga taattaccac caccacctct
    25981 agtgaatata tcatttttta ttccttcttc catgatatca acaattgaat ttatagataa
    26041 atcgtgtaat tgtatagctt gtctagttgt taagtgtatc ttatctaagt tgtgtttaat
    26101 agctatttca tagattttat taagttgata ctgagataaa actccagcag atactctaag
    26161 tcttatcata aaagattttt tgtctctttg agcataaaca ccatatccac cagaaaatcc
    26221 cttatattgc attttattta tttctccatt taaaaatttt gaagaatatt ctttaaaatt
    26281 aggtagttca tttaacaata tctttttaaa attatccatt atttcacctc attgttagtc
    26341 ttgtataaaa atatatctat tgtata
//
LOCUS       DAEQAF010000049        26013 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.051, whole genome shotgun sequence.
ACCESSION   DAEQAF010000049 DAEQAF010000000
VERSION     DAEQAF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26013
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.051"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(3..830)
                     /locus_tag="KRN00_002186"
     CDS             complement(3..830)
                     /locus_tag="KRN00_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1828051.1"
                     /translation="MKIKDNKAVFHVFIRIFIIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     gene            complement(878..2314)
                     /locus_tag="KRN00_002187"
     CDS             complement(878..2314)
                     /locus_tag="KRN00_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBH1828052.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENQYKK"
     gene            complement(2401..3270)
                     /locus_tag="KRN00_002188"
     CDS             complement(2401..3270)
                     /locus_tag="KRN00_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH1828053.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            complement(3428..4081)
                     /gene="phoU"
                     /locus_tag="KRN00_002189"
     CDS             complement(3428..4081)
                     /gene="phoU"
                     /locus_tag="KRN00_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBH1828054.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            complement(4109..4873)
                     /gene="pstB"
                     /locus_tag="KRN00_002190"
     CDS             complement(4109..4873)
                     /gene="pstB"
                     /locus_tag="KRN00_002190"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBH1828055.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            complement(4892..5716)
                     /gene="pstA"
                     /locus_tag="KRN00_002191"
     CDS             complement(4892..5716)
                     /gene="pstA"
                     /locus_tag="KRN00_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBH1828056.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            complement(5718..6635)
                     /gene="pstC"
                     /locus_tag="KRN00_002192"
     CDS             complement(5718..6635)
                     /gene="pstC"
                     /locus_tag="KRN00_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBH1828057.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            complement(7016..7462)
                     /locus_tag="KRN00_002193"
     CDS             complement(7016..7462)
                     /locus_tag="KRN00_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828058.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVS"
     gene            complement(7979..8659)
                     /locus_tag="KRN00_002194"
     CDS             complement(7979..8659)
                     /locus_tag="KRN00_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828059.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(8709..10724)
                     /locus_tag="KRN00_002195"
     CDS             complement(8709..10724)
                     /locus_tag="KRN00_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1828060.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGQLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGN
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILLPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPISAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFETYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(10796..11473)
                     /locus_tag="KRN00_002196"
     CDS             complement(10796..11473)
                     /locus_tag="KRN00_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828061.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(12053..12136)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(12369..13211)
                     /locus_tag="KRN00_002197"
     CDS             complement(12369..13211)
                     /locus_tag="KRN00_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1828062.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCSSNSGGSGDSGDSSKVSVSGS
                     TSIGPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSA
                     GLKETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREE
                     GSGTRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSL
                     KINDVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFI
                     KVNQ"
     gene            complement(13463..15247)
                     /gene="pepF"
                     /locus_tag="KRN00_002198"
     CDS             complement(13463..15247)
                     /gene="pepF"
                     /locus_tag="KRN00_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBH1828063.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYTKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KVIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADKFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(15313..15978)
                     /locus_tag="KRN00_002199"
     CDS             complement(15313..15978)
                     /locus_tag="KRN00_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBH1828064.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(16129..16290)
                     /locus_tag="KRN00_002200"
     CDS             complement(16129..16290)
                     /locus_tag="KRN00_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBH1828065.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(16368..16877)
                     /locus_tag="KRN00_002201"
     CDS             complement(16368..16877)
                     /locus_tag="KRN00_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBH1828066.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            17083..17301
                     /locus_tag="KRN00_002202"
     CDS             17083..17301
                     /locus_tag="KRN00_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1828067.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            17319..19265
                     /gene="feoB"
                     /locus_tag="KRN00_002203"
     CDS             17319..19265
                     /gene="feoB"
                     /locus_tag="KRN00_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1828068.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIMEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(19444..20499)
                     /locus_tag="KRN00_002204"
     CDS             complement(19444..20499)
                     /locus_tag="KRN00_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1828069.1"
                     /translation="MTIQDYMLETPVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(20547..21347)
                     /locus_tag="KRN00_002205"
     CDS             complement(20547..21347)
                     /locus_tag="KRN00_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBH1828070.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(21340..22131)
                     /locus_tag="KRN00_002206"
     CDS             complement(21340..22131)
                     /locus_tag="KRN00_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1828071.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(22171..22593)
                     /locus_tag="KRN00_002207"
     CDS             complement(22171..22593)
                     /locus_tag="KRN00_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBH1828072.1"
                     /translation="MKKFLIATHGKLSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(22609..23088)
                     /locus_tag="KRN00_002208"
     CDS             complement(22609..23088)
                     /locus_tag="KRN00_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1828073.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(23220..25976)
                     /locus_tag="KRN00_002209"
     CDS             complement(23220..25976)
                     /locus_tag="KRN00_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1828074.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYENSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIISKISTLITNRLDMYLNNVDTIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVVAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
BASE COUNT         8438 a         4577 c         2842 g        10156 t
ORIGIN      
        1 tattataagt tttcttgcca gaaattttta ggtgttatat tttctgtaat tggcaatatt
       61 gtatatcctc tctcttttaa gattcttata atattattta aagcatttaa actttgctct
      121 ttctcatgaa ttaatactac taattcatct ctttttcttc cataatataa tatattactt
      181 actatctgac ttgtagaaga cttccaatcc tgtgtatcca aattccagtc ccaaattaaa
      241 taatcatttg ccataagttt attatatgaa ccttctggca tatatggttt acttccgtat
      301 ggtaatctta ttaattttga actctgacca gttatttctt gtagagtatt attgcatgta
      361 ttaaattccc caactgttac ttctgggctt ttatataact tatgtatatc atgacttaca
      421 ctatgaaaac ctattgagtt ttcttcttcc aagactctcc ttacttcttc cttgtggttt
      481 ttcatattct gattaagcat gaaaaatgtc gctttgacat cattttcttt taaaatatca
      541 agtagtgcat ttgtatattt tgatggacca tcatctattg ttatgtatgc tactttttca
      601 gaagtagccc ctggaccttt tgtttcttct tgagatgctt tgtatatgat ttctcctaaa
      661 gtattacttt gagaaagcag ttccagtgta ttttcacctt ttgaacttat attttcaact
      721 ggaacattat taattttttc ctccaataat gttccagtta aaattaaaac agctataata
      781 aatatcctta taaatacatg aaaaacagcc ttattatctt taattttcat cccccatatc
      841 tcccttttat aaaagcataa gtttaagact taaaaagtta ttttttatat tgattctctt
      901 tcttattact ttttatatct ctactaaata tttttttaac cttttcttct tctttttctc
      961 ctaaagattc tactcttttg attcccaaag aagttaaaaa ttgtaataca tttaaattat
     1021 caaatggagt ttccatattc gtactttcac tatattcatc aacattctta gtaccttctt
     1081 ccacacttaa aatacgcttc ggacctccta cacagcctcc tacacacccc attccttcta
     1141 taaatgtagc ttctatttct ttatttagaa ctttctttag accgtccatg cactcttttg
     1201 ttccttcaaa tgccttttct tcaaatttta tatttttgtc aattcttcta actgataact
     1261 taactgcttt acttacacct cctgttctag cataaactct acctgaaagg gacgcctcta
     1321 ctctattact ctcatccatt attgctggat ttaactctaa tgcatcaaat atttcttgca
     1381 actctttaaa tgtaagcaca aaatcaactg catcttttat atcttctaac attgcttctt
     1441 tcttttttgc catacaagga cctatgaata caactttagc atctggattt aaaattttta
     1501 cagctctccc acaagcaatc ataggagaaa cggatggtga tacattctcc aatatttgag
     1561 gaaaactatt ttgtatcaaa ctaacccaaa taggacagca acaactagtt ataaagcatc
     1621 cttcttcgtc ctttttcata tgctcataat aatcatatgc ttcttttgca gtaagcatat
     1681 ctgctgccaa agcaacttct atcatatctt caaatcctat cttttttaat gcagttctta
     1741 atttaccagg gcttacatct ttcccaaact gtcctacaaa agctggtgca actattgcat
     1801 atacagggct ctttatatct tttaacaatt ttatcattgg tataaattct attttatctg
     1861 aaattgcacc caacttacat cttgatacac aatcaccaca agcactacat acatcttcct
     1921 cattacaatt aatatgctta cttcttatct tacatgactc atcttcctta ttattttcat
     1981 cacaatattt gcaagcatct gatattacag atattattgg tcttttgact tcatctaaat
     2041 ttacagcttc atgtagtgac tcttttaaat ttttatctgt atcttctgta acatccaatc
     2101 ccatagttac cctaattaaa tttaccatag tatctttatc aaattttcca ctaaaataat
     2161 tatttaaatt atcctttaaa tcttcattta aaattttatt aggtaagttt tcaatatcct
     2221 ctatatcatc attccacact gcttttacaa gttcgccaaa aagcttcatt ttatatattt
     2281 ctagtatttt agaattgtca tttctagtat tcataaaaaa tagtacctcc ataaattaaa
     2341 cttatatatg tttaatattt acaaagatac tattttttat ttattattta actactatta
     2401 ttaatatgat ttatttagct ttctcaacaa ctctatttca atcattattt tcattagatg
     2461 atagttgaat acagggcttt tttcttcatc tatattccag tctagcttat ccacattata
     2521 tgttttctta aggtatttat atgtatgctc tttcaaataa agtttatttt caagtaactc
     2581 tatagactgc atatgaaaat gtatttctct acatatcctt aaggcattct caattttttc
     2641 tatattagtt tcactcaaac tataatccaa ctcatcaata agttttgaat atatttcttc
     2701 taatttttct acttcttctt caaatttctc tacatttaaa ttttcttttc taagaatttt
     2761 atcttcaata agcaacattg aaagttcttc tatcttttta aactcatcta taacactatt
     2821 tagataattt ggtctagcaa cataataatt aacaagtact ccaaacaaaa cacccacaga
     2881 tgtatctaac accctatgta aagaataata cacagggtca ctatttccta cacctagatg
     2941 tatagccaga aaggttacac aggcaactac tactgacttt attttaaaca gattgcataa
     3001 atatattgag cacattactc ctagaccaca taaaaatggg tctccagctt taatgatggc
     3061 aaatatgaat cctattatac cacctaaaat agtaccttcc actctattga ttcccgtctt
     3121 taaagaacct tttactgtat cttgaacaga aattatacat gctaccagag aataaaacat
     3181 attctctact aaatagtcac caagaatcat acataaagtg acactaattc ctgtttttat
     3241 agtcctcata cccatctttt gaagtttcaa agttccacct cctaaaaagc accttatata
     3301 aaatacgcat cctcatattt aatatgttcc tagtatatca caatttttta aatttaccca
     3361 ttaatcatat ttttttatca attctttctt aatttagaca ataaaaaaac tgctttaaag
     3421 cagtttttta tcctatctca accattttac cctcaattgc aaaaattatc ttctcacata
     3481 catttgttat atggtctcca attctttcaa ggtatcttcc tataagtaga agttttaccc
     3541 cttggtctat ggtatttgag ttttcatgca ttatttttaa acaatcaatt tgtacttgtt
     3601 catacaatcc atctacaata tcatctttag ttccaacatc ataagctata cttgcatcaa
     3661 ataagattaa agcttctcta gtctgagaca tcatagactt acattctttt gccatcttag
     3721 gaatatctat tagctctttt atataagcct ctccacctat cttcaacatt tctctagcta
     3781 tatttgctgc ataatctcct attctttcca gctctataga tatattacct aatgaataaa
     3841 taaatcttaa gtcccttgcc attggttgct ttaatactat tagctctata ctcttatctc
     3901 ttatttcttc tcttaattta tttatttctt catcatcttc tactactttt cttgcaccct
     3961 ctaaatcctt ctctatcata caagtcacag acttttctat tgcttcttca catttttcca
     4021 tcataagcac tgtttgttct tttaaagtat caatacttat atctaaacta ttattgacca
     4081 ttgtctaact cctttatagt tatatatttt aaccaaatct acctgttata tagtcttctg
     4141 ttcttttatc tacaggagtg gtaaacatag tttttgtatc gctaaattct ataacctctc
     4201 catttaagaa aaaagctgtt tcatctgata tacgagcagc ttgttgcata ttatgtgtaa
     4261 ctatgactat tgtgtagtct ttttttaaat cctctataag ttcctctact tttaatgttg
     4321 aaattgggtc taaagcagat gtaggttcat ccataagaat aacttctggt ctcatagcaa
     4381 ttgctcttgc tatacatata cgctgttgtt gaccaccaga aagtcctagt gcagatgatt
     4441 taagcctgtc tttaacctca tcccaaatag ctgcaccttt taagctttct tctacaattt
     4501 tatctaattg cttcttatct cttagtccat gtgtacgagg accatatgcc acattatcat
     4561 atatactcat aggaaatgga tttggctttt gaaataccat tcctacttta gtacgaagat
     4621 ttataacatc atctgaggta tatatgtcct ctccatcaac agaaatgttt cctttaattg
     4681 ttacatcttc gattaagtca ttcattctat ttaacgttct tataaaagtt gattttccgc
     4741 atccagatgg acctattaaa gcagtaacct tattctcttt tatatccata tttattttct
     4801 ttaatgcttg cttatcacca taaaataaat ccaaatcttt tacactcatt tttatcttat
     4861 cgattaattc cattattcac acctcttaaa tttaataatt agctttattt aatttcttag
     4921 caacaaatct tgctagcatg tttagtgcta atacaattac tattaaaaca attcctatac
     4981 tggctgctgt tgctatatct ccactctctt tagtcagtaa gtatgagtgt acagttaatg
     5041 ttcttgcact atcaaatatt ccacctggca tcttggctac agtacctgct gtaagtaata
     5101 ttgcagctga ttctccaatt atacgaccaa ctgataagat tactccagat aaaattcctg
     5161 gtattgcact tggaagtact accttatata aagtttgaaa ttttgtagct cctaatgcca
     5221 atgatgattc tctataagct tgaggaactg tttttaaagc ttcttctgtt gtacgaatta
     5281 ttactggtaa tattattatt gcaactgtaa gtgaacctgc aactatggaa tatcccattt
     5341 ttaatgtaac tacaaagaaa attcctccaa ataatccata tactatagat ggtatccctg
     5401 ataaactttc agttgcaaat cttatagctg taactgcttt tcctttttta gcatattctt
     5461 gtaaatatat agcagccaat attcctatag gagttgctac aactatagaa accactactg
     5521 tatataatgt tgtaattatc attggaagta taccaccatc acctgatgct gaataattgc
     5581 taaataagaa attaaaattc atgttgccaa ttccctttat aaatataaat cccactataa
     5641 ctactaatga tactattgta aatagtgctg atagatatac taatgacttc aatagattct
     5701 ctttgaactt tctcatctta atttaccgcc ttatttgaaa gtttatttaa aactaagttt
     5761 aaaattaata taaatgtaaa caatactact ccagttgcaa atagcatttc ttgatgtgta
     5821 ccaaatgcgt atcccatttc aagtgctata ttagttgtaa gtggtcttac actatctgtt
     5881 attgcagttg gcataactgg tgagttgcct gcaacaagta ttactgccat tgtttcacct
     5941 aaagctcttc ctactcctaa cactactgcg gctaatactc cagattttgc agcaggtaat
     6001 acaactttga atattgtttc tatttttgat gcaccaagtg ctaatgaacc ttctttgtat
     6061 gcttttggta ctgctcttat tgctgtttct gatacagata ttattgttgg taacatcatt
     6121 actgctaata ctattactat tgctaacaaa ctttgacctt ttggaagatt aaatatactt
     6181 tgtatagttg gaactatcac tgcaagacca aatacaccat ataatactga aggtatacct
     6241 gctaaaagtt caactgctgg tgacattatt tttgctaatc ttttaggtgc tacttctgct
     6301 ataaatacag aggttaatat accaacaggt actcctatca caagtgctcc aagtgttgca
     6361 aatattgatg ctactatcat agatgatatt ccaaatttat tggcagaagg aacccaatct
     6421 gcaccagtta aaaagtctat aaatgaatat ccttcaaata taaatggtct taatccttta
     6481 taaaatacga atcctattat caaaagtaaa cttgcaactg ctactaaagc actaagtaga
     6541 aaaatatttt ttgctacttt ttcaattacg tattttgtct tattgccatt attgtcattt
     6601 ttttctaaac ctactaatct agattttact atcataatac cctcccatta aaatatactt
     6661 atcgattttc gttctgtatt caaaatttaa ttttttataa ttcgtcttca tcaaatttcc
     6721 tatactttta ttctactttt tttaagttaa atctatatta ggattaagtt aagcaagtgt
     6781 aaaattatat ttacttttta acattaattt tacttttaaa actatatttg acatttactt
     6841 tacaatatac tgttgtttct ctatattaaa atagcagata tagataataa tacagtttat
     6901 gtataattta ttacctatat ctgctattaa gatttgttaa ctaaatttaa cttttatact
     6961 acatatataa ttattgtatc ctctagttta tatcactatt atttccatca aattgttacg
     7021 atacttgatg tttgcaatag gtacgaatag ccaaaaatat aaaaataggt atttctatca
     7081 ctgagaaaaa cagtataatg tgtggtgtcc aaaaactcat acctcctaag tgtaagaaat
     7141 taaatgatgt catttgatat aataaactaa tcttaaaacc aattccccct ggtggtaata
     7201 ggtatccaat ccaactaaca cctattccca taggaattaa gcaaatagaa aaagcaatca
     7261 gcatagaagt aagagaatcc ttacattttg cagataaaaa taatgttaaa ctaaccattg
     7321 caagtattga aattagacca ccaatagcta taagaatctg tgcttgtagt aaatttatat
     7381 ttactagact aattacagaa aacaacattt gaaatgaggt tttcaaacat tcagtaccaa
     7441 aagctaaatc agaaattgcc aaatggatag aaatacatat aacaaacatt attataaata
     7501 tagaaaatag agctaatatt ttagtaaacg ctagacgaat atgtccatgt ttcgtacaac
     7561 gaaggatgct atctgattgt gtctgatact caccagaaaa agtaggtgca gcaattgcaa
     7621 cacatataat taataatata aaaatataaa atattatata atcgaaagca tcttctggat
     7681 ttattaagaa attcttaatc ttattattta actattttat tatttaatat atattaaagg
     7741 taaaaaataa tatatagatt tagatataca atttatttat cttttcaaat ataatctata
     7801 aaataatagt tctgttacgc atttttttat ataataaaac tgactgtaat ttaattggca
     7861 aagtctagaa gaataggctt tatcaattaa attacagtca gctattttat aataatttag
     7921 tttagatatc gttagtattt cacatttata acaattatta atgatattaa tatatttatt
     7981 attctttatt aaaataatat cctgctcctc ttattgttat aattttctga ggatttttat
     8041 aatctttctc tattttcttt cttaatccat tcactgcaac taccacacta tagttatcct
     8101 ctaagtattc attcatccat acatgttcat atatctcttt agtagtcaaa gtcttttcag
     8161 gattctctat aaaaaagttt aacaacttat tttctgttgg agtcaatttt attattttat
     8221 cttctaactt tattactcca ctagttctat tatattcctc taattttgta ttattttcat
     8281 tattatttac atatgagttc attcttctta aaatagcttt tacttttgcg tataatattt
     8341 ctaaatttag aggctttatt aagtaatcgt ctccaccaga atttaaagca tttaaaatgc
     8401 tttggtcttc atttatataa gtcatataaa caattggaca agtagttaca tttctaattt
     8461 ttttacaaag agtccatcca tcaccatcac ttagaattat ttctaaaaat attaaatcat
     8521 atttattgct aaatattttt ccaatagctt cttcacaatt atatgctaaa tctatactta
     8581 ttcctttttc ctccagaaat ccttttagct tctggcaatt atccttgtct ccatctatta
     8641 tcaatatctt agtttgcatt ataatcactc ccaaatatca ttattctttt atattaaata
     8701 agctattatt ataaaaaaca tagacttaat tttattgtaa aaacagttcc ttttcctagt
     8761 tctgaatcta caaatatttc tccaccatgc tctcttataa tggatttgac aatatatagc
     8821 cctaaccctt gcccttttgg ctcattattg tctctttctg taaagaatct gtcaaatacc
     8881 tttggtatat tttctggagg tatacctttt ccattatcag aaattttaat aattgcaaat
     8941 ccatcttctt tatccattga taaaattatc tttccatcaa atggagtaaa ggtcaaagca
     9001 ttataaatta aattctcaaa tgctcttgta agcatctctt tatttatctt tgcatatatt
     9061 tttttctcca atacgtaagt ttcaaagttt acaccacatg cttgtgtatc tggcaaatta
     9121 ttttcatata tctctttaat aaaattattc agacatattt tttcactaat accaatgctt
     9181 ttatcttgtg atgtaaattc ttgcaaacta cgtactctat tttgtacttc atttgacttt
     9241 tgatttatag cataaagata ggttcttgtc tcttcatcta catgaatatt accaaccttt
     9301 atcaaatcta taaatgcttg tatagccgaa ataggtgcct ttaaatcatg tgctacatct
     9361 gccaagaatc ttttacgttc atttaacaat gttgtaagtt cattagttct cacttcaact
     9421 tcatgttcaa gattccttgt aagtttttca ttctctttta ttattattct attcctgttt
     9481 atcatcataa cagaaaataa aataacaatt acaaacccac aatattctgt ttgccaccct
     9541 gtaaatatag gctcaaatct attactcgta actgcatcaa ataatatgct aattccaaaa
     9601 acagtgttta ctgaaactaa aatataagaa cttatatgct cagagcatgt ctttttatat
     9661 attgaaacca gcgaagacat taatatatat ataaatacaa tatatttata tatgtctatt
     9721 aacttcccat atatgttgac aaagtacata tcatatggaa gaagaataat tggtatcact
     9781 atagatatga tactcattgt aattcctaat ggtaaaatta aaaatctata cactttattt
     9841 tcttctattt tggatatact tccatttata caaataatac ataaaactac cataaaatat
     9901 gacaaatctt caaccgcata tgtaaagctt accaaaggca gtcctaacaa atgtacaaag
     9961 ggataggata catggatggc aaagaaaaca cacatacatc caaaatataa gtaaatttta
    10021 cttttgtttg aaagaaacca tacagacaat gaaaatatag ctattgcaaa agtcgtgaag
    10081 caaattatac tataaaaaag taatcgataa aacatcatat tacttatgtc ctttgtttct
    10141 cctaatgcag gcggataata caaaccacta taataatgtg aaaaattcga tacattgatt
    10201 ataatttctg tatttttctt tgcaataaaa cttactactg aatttttaat tttgggtcta
    10261 tatttttctg ttcctacatc tcctaattta gaaaccattt ctccatttat ccatacttca
    10321 cttgcggaaa aaatctcagg aagctctaaa cttagtagct tatccttgcc ttcatttttt
    10381 attctcatac gataagtagc attcccatat ggtgactgat tcccctttct catagaaaaa
    10441 tctggatatt gacctataaa aacatattct ggttttatat cttgctctgt aaaatcattc
    10501 ggtttaaata ttttatgatt ataaaactcc cagtcatcta tcaaaaagac aagttgccct
    10561 ttagtgaaag tatcattatc tatagttaaa attccattac ttgctctaat agacttatat
    10621 gtatatttat tatcatattt atacagaaga tttaatcctg ttattgccaa cagagagact
    10681 atcaatacaa tgagagttcc ttttagtata ttatactttt tcattgcatc aaccacatct
    10741 ctttcatagt cgtattaaat aaaacaagaa ctatttatta attacagtat ctcacttatg
    10801 gtacaaactt atatcctttt ccccatacgg tttgaatgta ttgatgctcc ctgcttaaag
    10861 aattaatttt ttttctcatc tgtgcaatat gaacctgcac tgtatgttga tctccaatat
    10921 caggcatttt ccaaacttgg ttatatatct ctatcttcga aaatacttgt tctttgtttt
    10981 cagctagaaa caataatatt tcaaattcca tagtagttaa atctatactt tctccatcaa
    11041 aagttacttt tcttgaattt acatttatta ctaacgctga aaactttaac acattaggaa
    11101 ctgatgtaat atttttgtac tgcctcatac gagcatatat tctaagttca agttctttta
    11161 aactataagg ttttgttata taatcatccc ccccagctaa aaatccccga actttttctt
    11221 cttcatgctc ataattagat aaaaatatta taggtatgtt aaccttttct tttatatcat
    11281 tgcacatttt atatccatct atatctggca atgaaatatc caaaattata cagtctaaaa
    11341 ctatactctc tactatatcc atagcatctt tagcagtctc tgatgtatat acattaaaac
    11401 ctatattaga aaaataaatt tgatttatgt ttaaaatatc aacatcatca tctacaacca
    11461 gtaaattata cattacacca ctccattcaa aggtatttta attataattc caagttttat
    11521 agttattaca aattataatg ttttattttc atatataact ggtattatta ttttataata
    11581 tctttacaaa ctagactata atacttaagt atttttgaat aattcttgaa tattgtatta
    11641 aacattaaga ttcattatta aatactaatt aaagtctccg attgttggag aatggagctt
    11701 aaagtcattt tcacgtataa atttattatt tttctagaaa cttgtctatt ggctagtttg
    11761 agtattgatt tatatgattt atatggttat aatataaaat aaattgtatt attttggtaa
    11821 atatattgtt acaaaaggtt tatattctgc atctcaatgt ttataaaaac tttattttct
    11881 tattataata ctattattct tttaaaaaaa tttccctttt ccaacaaatg gctactttaa
    11941 aagccaaaat tttacctatc aataaaaatc ttaacgacta atactcttat tttcaaattt
    12001 tgcaacatat ttgttaattt taaaacaaaa aaagactatg caatataaaa attatattca
    12061 tagccggttg caccactaac tccatatatc tctagatgcc caataataag atatacttct
    12121 cagtttctaa aatattttta ttaaaaatct tttatatatt ttcataaatt tcttttttat
    12181 tctaacattg taatattatt ttgtcaatat ttccatattc ttagatataa gatactaaaa
    12241 tacctatttt atctaaagat atttatattt ctacattcaa taatagacaa taccctgcaa
    12301 gttaaagcat catttttatg agcttatctc acagggtatt atatgtttac tttatattat
    12361 aactcttgtt attgattaac tttaataaat cctttttctg aaacaagtgc ttgtccttca
    12421 tcacttaata tataatctat taaagcttta cctttttctg acaaaccatc ttctttatta
    12481 actaatataa atggtcttga tattggatat ttattagcta ttacatttgc atcagttgct
    12541 tcaacatcat ttatttttaa actatttact ttctcatcaa catatccaaa tgatatatat
    12601 cctatagcat tttcatttcc ttcaactgta gtttttatat ttcctgaacc atcacttatt
    12661 tgtgcatctt tagttagttc ttctgaatca aaccctacaa tttcttggaa tccatctcta
    12721 gttcctgaac cttcttctct tgatactatt actattggtg catcatttcc tcctacttct
    12781 ttccagttag taatctttcc tgtatatata cctttaactt ggtccattgt cagatttttt
    12841 actgagtttg cagtattagt tatcaatgct ataccatcta ttgctatttt agtttccttt
    12901 aatccagcac ttttttcttc atcttttaaa tctcttgaac tcattcctat ttcagatgtt
    12961 ccttctatag cattttttat acctccagaa gaaccaatct gttgtacttc tacactaaca
    13021 ccttgatttt tttcttgaaa cttttctccg atagtttcca taagaggacc tattgaagtt
    13081 gaacctgaaa cagaaacttt gcttgaatct cctgaatcac ctgaacctcc tgagttagaa
    13141 ctacatccta ctgctaaagc tccaactaac attgtactag ctaaaagaac gcctattttc
    13201 tttttaaaca ttttacttac ccccgcttat attttaattt tttgttgtca tttttctata
    13261 ttttaataat acagattctt tgttaaatga atattagagc agggttaagt aaatgtaaat
    13321 attgttaaat acatgtaaaa acttaatttt atatgattta ttcttaatta gattaacttt
    13381 ttaaagttac tttaggcaga tataaacata atacaactca tattatcaga agtcttcttt
    13441 gaagctatca acctatcaca tcctataatt ctttttctag tttattaact aattcagcaa
    13501 atacatttaa ggcttcctct atagattctt ttttcgtcat atctacacca gcagatttta
    13561 attgttctag tgggtattct gaccctccac tttttaagaa gtttatatat ctatctactg
    13621 cagtacttcc ttctgaaagt atctgttgac ttaaagcact tgcagcagaa aaccctgtgg
    13681 catacttata tacatagaag tttgaataaa aatgaggtat tctcgcccat tctattccta
    13741 tttgtttatc tactattgca gattttccgt aatacttttc atttaatttg tagtatatat
    13801 tagtaaattt atcagcagta agtggttctc cactctctac cctttgatgt acaatttttt
    13861 caaattcagc aaacatagtt tgtctatgaa ctgtagttct aaattgttct aaataataat
    13921 ttaataagta tatagtttca tccttagact tagaattttc taataaataa tttataagaa
    13981 gtaattcatt taatgtagat gcaacttctg caacgaatat cttatagtcc gaatataaaa
    14041 atggttgact tgttcttgaa taatggctgt gaacagagtg ccctaattca tgaattaaag
    14101 tgaatagaga attaaggtca tttttatagc tcattaatat ataaggatgt gaatcataac
    14161 ttccccaaga ataagctcct ccttttttgc cttcattatc atatacatca atccaccctt
    14221 catcaaaagc actttttatg accttcaagt attcttctcc taaaggttta agtgcctcta
    14281 atatgatatc ctgtgcttta tcatatggta tatccatgtc aaatttatct gtcaaaggaa
    14341 catacaaatc atacatgtgt atttcattca atcctaaaaa tttcttttta agctcaacat
    14401 atttatttag attaggaata cttttatcta tagctgatat aagattattg taaacatcta
    14461 aacttacatc atctgaaaat aaagacgctt ctattgctga attatacttt ctagtttttg
    14521 cgtaaaatat ctctgatttt attccaccat aaagcgttga ggcaaatgta tttttatatt
    14581 tctcatatgt tgaaaattca ccttcaaaag cgtcttttct aactctacta ttcttacttt
    14641 ttataaataa agagtagttt gaatgagaaa gcttaacctt attcccctcc tcatcttcta
    14701 tctcaggaaa ttccatatct gcatatgcta acatatcgta tacattttct ggaattgtcg
    14761 ataattctga tgtagctgca agtatttctt cctctcgttc actcaaagta tgtggtttat
    14821 ctctcaatat atcctttata tattttgtat aaaaggatag cttctcatct tttaagtatt
    14881 cacttaactt attctcttct atcgccagta tttctggaac tatataagaa gtagccacac
    14941 ctaaatcagt agataacatt tctgtcttag tggctcttcc ttgattatca ttaattctag
    15001 tatcttcatg ttgtttcata tgagtatata catataaatt ttgaacaatc ctagatgcat
    15061 tttcagagat atttaatact ttatataagt tctccttact ctcagaaagc ttccctttat
    15121 attcttttac ttcttggata agatttttta ctttacttat gtctttttca atttcctctt
    15181 tactggagta catcttatct atcttccatt tgtacttttc ttctattgta cttctatcag
    15241 ttcccatatc atacacctct attttaattt gttttatact ttattcactt tacaaaatat
    15301 attgtatata ttttagtcca aataatctac atttattact ccttctatca tatttatttc
    15361 tttcataaca tcgtgtaagt gtattctctt agcataagat acaaaaaaat taaccttcca
    15421 gtattcttca ttacgacatt ctatttccat atttcttacg ataagttgat ttttttcaaa
    15481 tttatcatat aaaaaaggta tagagtccaa attgcttaat tttaatatca atacattctt
    15541 ttcttggcta aataaaaatg tattgattat cctaagcaca aataatgcta tcattacaaa
    15601 taatccacct agaattgcca attcataata accatatcca actgctatac caatacatgc
    15661 agttgcccac atcccagcag ctgtagtaag cccttttact ccacctttat tttttaaaat
    15721 tgctcctgca cctaaaaaac caattccaga taatacttga gcaggcattc ttgctgggtc
    15781 agcatttgta tacaaattat aatcaaagaa taattgaatc gaagttattg aaacaataca
    15841 agaacctatt gcaattagta tatgtgtcct aaatcctgca aactgtctta ttttttctct
    15901 ctctaagcct attattcctc ctattattag tgctaatagt aaccttattg ctatctcctt
    15961 acttcctata tcaatcataa tataaaaccc tcctgactta attacaactt atgtcctaca
    16021 gataatttac acatcagaaa tactatttta tatcttaata ttattattaa tatatgtaaa
    16081 atatagccat ctgttaattt ttgatacaaa aaaacccaca actgtgggct atttgcttag
    16141 gtacatgtat ttatttatta atatatctat tttcttactt gattctacta actcttcttg
    16201 aaatatttct ggatattcta tgtatgtatt tatctcttcc ctaactgctt caatctcatt
    16261 ttttaacgct tctaattcat tgttcgccat aataatcacc actattacaa atttgtatat
    16321 ttttatatac attttatcaa acaatattat attttgtcaa tattatgtca ataaaactta
    16381 ctataaaaat gctttaattt aggtattgta tacctggata ctaagcctac aaacatacca
    16441 gttactaatg atgccattaa cataaatggt aagtacccta tagcaagtat attttctatg
    16501 attaaacttg caactattaa ttgacctata ttatgcccta ttgcacctat aatgcttatc
    16561 cctattagtg ataaatcttt tattttactc gctaaataca taaataaaag actcagataa
    16621 gctcctccta tactaaatag tagatatgat aaagggcctg caaatattga tgacaaaatt
    16681 accctgatag taacaattat aacagtatct ttgacaccta acaacattaa tgaaattaaa
    16741 gttataatat tgctcaaacc caattttgcc cctggaaata taactataag aggatttggt
    16801 atatatgtct ctaatacata taaagctaaa ctatacccta tcataagacc taaaaatgtc
    16861 atttttctag ttttcattaa gttaactcct ccaaatttta tctatcatct tacattataa
    16921 tacaaaatat ataaaaacac ctaatttaga ctaaaatatt tttaatctat ttagaataaa
    16981 tattagttat ttcaatgtgc aattacctct ataaatcttg actttttgta tcatacttgt
    17041 tacaatttta atgataatga atttcattag gaggtgttaa taatgactgt ttacgattta
    17101 aaaataggag aaaaaggatt tattaatagt atagatggag atattaaatt atctaaaaga
    17161 ttgcttgcac ttggatgtat aaatagtact gaaatagaag ttaaaaaggt tgccccactt
    17221 ggagacccaa ttataattag atttagaggc tttgaccttg cgattagaaa atctgatgct
    17281 aaaaatattt ctttacaata atagaggagg agctacccgt gattaatgta gcattattag
    17341 gaaacccaaa tgtcggtaaa actactgttt ttaatctact tacaggttca aatcaatatg
    17401 taggtaactg gcctggtgtt actatagaaa aaaaagaagg atttcttgga aaagagataa
    17461 aggttgtcga tttacctggt atatatgcaa tggatacttt ctcaaatgaa gaaaaggttt
    17521 ctaaatcata tttagaaaat gaagatgttg atgtaatagt aaatgtagtt gatgcttcta
    17581 atttatcaag aaacctttac ttaacaactc aacttatgca atttaacaag cctatagtta
    17641 tattgcttaa tatgttagac attgcagaat ctaaaggagt taatatagat gccaaaaaat
    17701 taagtgaaga acttggagta attgttgttc caattatagc aaaaaagaaa aatggtgttg
    17761 ataggataga agaagagatt aagggagcta cgcaaaaagc ttttatatat cagaaaaact
    17821 ttggaagtga aacagaaaca tataaaaaat tagaatccat tttatcgaga tgtacaaaaa
    17881 ctacatatac acaaaagaaa tctattagtg ataagataga caatatagtc ttgaatccta
    17941 tattagcata tccaatattt attggtgtat tgttcctctt atttaaattt acctttgact
    18001 gggtcggagg accactacaa gagggatttg ctagtcttat agaggcttat atttctgcac
    18061 ctgttagtga tatgttatct aactctagcc catggtttaa atcacttata gttgatggaa
    18121 taattggagg tgttggtggt actttaccat tcttcccttt aatatttaca ttattctttg
    18181 gtatatcgtt gtttgaagat agtggataca tgtcaagaac agcattttta atggataaag
    18241 ttatgagaaa ggttggtcta tctggtaaag cttttatacc tatagttatg ggtatgggat
    18301 gttcttctcc agctataatg gcaactagaa cattggaaag cgaaaaagat agaagagtta
    18361 cagctcttat tgcaccactt atgacttgtg gagcaaagct acctatatat gcactatttg
    18421 tagctatatt ctttccacat aatgctgctt tagtaactac atcactgtat ttggtgggta
    18481 tagttatggc aattgtagtt gcattattct taaataaaac agcctttaaa acagaggctg
    18541 aaccatttat attagaatta ccagaatata gaatccctac tatagatgca cttattaaaa
    18601 atacttggaa taaatcaaaa ggtttcttga taagagttgt tactgtcatg tttgcaatgt
    18661 cagtcgtaat ttggggactt tcttcattca atgtttttgg atatacagaa gatataaatg
    18721 taagcttctt ggctactcta ggtcatatta tatctcctat attcaaacct cttggttttg
    18781 atgattggag aacttcagtt gctattttaa gtggtcttgg agcaaaagaa atcgtagtaa
    18841 actctttaaa tatactatat ggtaatctaa ctgttgtctt accaacaata tttaatggag
    18901 ttactgcata tacattcttg atatttactg ctttatatac tccatgtata gctgcacttg
    18961 caactatgaa aaaagaatat ggcaataaaa tgatgtttac atcatttgca tatcaattta
    19021 tactagcatg gataatggct tttatagtta aaagtatagg tggagtacta tttatgggta
    19081 attcaataat ggaagctttg ataggtggaa taattatagt ccttgcactc tttattctgt
    19141 ttaataaatt caagtctaca aaaaacggaa atgtctgtag tggatgttct atttgttctg
    19201 gatgtccaag tgctaattct tgctcaagta aggaagacag caataaaaaa aataatgcac
    19261 actaatatat aaatatttta gtttaaaata agataaaagt gggtgtctca aaattaactt
    19321 tttagttcat gaggcactct tttttatata aaatcaaata tattttcatc atttcaacag
    19381 taaaaaagag cttatctagt aaaaaagagg cttatctcta ttttgagaca acctcttttt
    19441 ttgttactta ttcagtttct tgctacctaa cttcatgtgg aacctagtat cttttggaac
    19501 acttgggtct acacctctta atgtaggtat ttccccacat attagttgta taggtactat
    19561 aaaattaaat gtttgatagt aaggattatc tgtgatatca atctttaaat ttttatcatt
    19621 ttctgtaaca tctctaccta tagcaaatac attttccgtc caaccagaaa gtacatcaat
    19681 catcttagtt actctaggtt cttttcctgt atctagtata aatatagtag aatcactatt
    19741 tatagcatta tatataccat gtataaactc ttcaaactca tacccagtta caggtattct
    19801 cattgtttcc aataatttta atgctgcttc taatgtatct ccatatatat cagagtgacc
    19861 tattattctt atttctttag aattaactaa cttttctttg tttctttcaa tccattgttt
    19921 agagagctta tacactgctt caaatctatt aattgcatct aatatcttat ttatttcctc
    19981 attgtacttt tcactagata ttataccttt ttctctagct atttgaagac ctaataacat
    20041 taagtttaac tttgtacaat aatatccttt tgttttagct ccagattttt cttcaccaca
    20101 atttactgtt aatatataat cagaaatctc atctattaaa gcattcttac aacctgccat
    20161 agatgctatt ttacagccct tatcttcagc taacttcata gcgttgtatg tagaataact
    20221 actcccacct tgagatacac ctactactag ggtattttca ttatcaaact tgaatgtatc
    20281 ttcagttatc ataaatggat acattttcac aacatctata tctaataaat tttgtaaata
    20341 tggttgcact tgcactcctg agtgatagct agtacctgaa cctgttatta taatcttttt
    20401 tagatttgtt ctcttaactt cattaaataa gctatctgca ttagatataa tttctctcat
    20461 tctaactggt gtttctaaca tataatcttg tattgtcatt ttatacacct tccttatcta
    20521 tatattcaat aaattataat taatttctat aacaaaccta tagcatgtaa agcgattcct
    20581 gttactatag tgcctatagt taattttgtt acacttacct ttctctttaa catgtagtat
    20641 attacaaatg caaaggttaa aggtaacata ttaggtatta ttttatctag tatatcttgt
    20701 aaaattactt ctgcaccatt taagttgaat ttcagaggag tagttatact caacatagtt
    20761 gcaaccattc ctcctacaac gaataaacca acagttgtag ccatagacat tattttctcc
    20821 ataagtccct ctctttgtat tctttcaaga gaatttaccc ctacttgata accatactta
    20881 agtccaaata ttctaagggc aaatgctggt atattgtata atagtaagaa taatagtggt
    20941 ccaaagatat taccttcttt tgcaagtgat actcctactc ctgctgctat aatcctaaat
    21001 gttccccaga ataatgaatc accaattcct gcaagaggtc ccataagagc tgttttaaca
    21061 gcactaattg aactttcatc aaattctgga ttattagcat tctcttcttc catagcggct
    21121 gttataccta atatagcagg aactaccact gtcgttgtat taaaaatctc caaatgcctt
    21181 tctattgctt ttgcttgatt ttctttctta ttgtatagct tctttattgc aggtaacatt
    21241 gaataacagt aacctaagtt ttgcattctt tcgtaattaa atgcaccttg aagagcaaat
    21301 gaacgccaaa acatacttct taattctttt tttgttaatt tattcaaagt caatctctcc
    21361 ttccgttaaa gtattgattg ctaattgagg attttgatta ttttctttgt tattgatata
    21421 aaagtttagt acaaatgcta cacatactcc aaataaagct atagcagtta tatctaatcc
    21481 accataagat gctaacaaaa accctataaa gaaaaataca gacatctttt ttgaaagtaa
    21541 catatccata agcaatgcaa aacctactgc tggcaacaat gttcctgcaa cacccagtcc
    21601 gtctaatata actttaggta ttgcatttat taatgctgta actttatcag caccaatcat
    21661 aattgctaaa aaggttggaa ctgatgtact taaaaagaat aatattactg gcaaccacat
    21721 cattatggta actttcttaa aatcagcctg tttagcatag aaaactgcct tttgagaaaa
    21781 gtacgaattt attattctaa ctaatactcc aagagattgt gctaagactg ctactggtac
    21841 tgctactgct aaagcaactt ctgcaccatt acctgataat atagcaaaag ctgtacctaa
    21901 tacacctccc gttactacat ctggaggagt agctgcacct attcctgcaa ttcccatcca
    21961 aattaattca agctgtgcac caatcataat tcctgatttt atgtctccta aaactaatcc
    22021 tactaacata cctgtaacta ttggcctatc aagcatagat tgaccaaata tacgcccatc
    22081 tagtatacca actcctgcta taatagctaa catagtagct tgtactaaca tattgaacct
    22141 ccattttaac ttagtttaat ttacattaaa ttacattaca tttttgattt tgttttgatt
    22201 ttctaataac tcatttacat aaacaattcc attttttgct tcctctaatc ctgatttaac
    22261 tattagtttt gtatcctcct caactaataa aagtatagat aaaagcattg gtaaatttac
    22321 tcctgtcaat aattcaaatt tgaacccttg taaaagtaag tttgtacata tgtttgccac
    22381 acttccacca aaaacatctg ttaagacaac aaattcttca ctatctttat tatttgataa
    22441 tatacttcta atttctttct cagcatcatc tgctgattta tccgttgtca tacaaaaata
    22501 ctcaatatta gttaatgaac caattattaa tttacttgtg tcaacaagct ctctggacaa
    22561 ttttccatgt gttgcaatta gaaatttttt cattctcttt ctcctaaatt attttattaa
    22621 atctgatagt tgtttctttt tgtctctagg taacattcta aattctatat caatccctaa
    22681 atcacctatt tgtttaaagt tatttatatc atcatcatca acagcaacta aatctgtaag
    22741 tttcttcttc ccttcctcat atcttaatcc tcctacattt atttctttta atactcctcc
    22801 tgaattttta gctacaacta aagcatcttt ggtatttttt actaacacta atacattgct
    22861 tttctttgaa gaagcaaatt tttctactat ttctccagat tcctctaccc cccttatata
    22921 taaagttaca ttgctaggtt tcgctaagtt cagtgacata gctttcattt ggtcattttt
    22981 tgcttcatca tttgcaacta gtattacatt tatacctagt gatgttgccc atccatatgc
    23041 aacctgacca tgtatcaatc tgtcatcaat tctcatcaaa gataccattt tccccaaatc
    23101 ctccatcata cattaaaatt tttattgttt atactctcat ttatctataa aagcaaaaag
    23161 tatgccaaat actggcatac ttttttaaat ttcattcact tattttgtaa tcttgtattt
    23221 tactgtggta gaccatagat aatattataa atatatccta tctctgaaat tggtatttgc
    23281 acactataac tcttttctag cacactaaat gcatttttta ttagttttac ttcactatga
    23341 tggtttttga ttaacaaatc catatcagta tactcttcaa tttcagtttg tctaactaat
    23401 ctttcaatca tacaacttaa gtgaacatat aaagaaatct ttttatcatt tgaaagtttt
    23461 ttcttttgaa tattttctat agcattaatt ccttcttcta ttctctctat tatctttttt
    23521 gaatctaaaa tagttagact atctattact ctaattaatg aaaaattctt tacaatagaa
    23581 tcatttatgt tctttatttt ttcattttct actactctgc taaatattct aaaaacatca
    23641 tcttctcctt ttcctgatat tatatcctct aataatataa aatctacccc attcacattt
    23701 ggattggcag ttcctactat agccaccaca tcatacattt caaaaactgg ttctttatct
    23761 cccatagaaa caagactatc ataatcataa ggtattattt tgacatcaac tattccaatt
    23821 aaactttcgg aaagtagatg ttggattttt atagcagtac ctatccctgt aaaacaagat
    23881 gatattatag catattcttt atttttttga ggataataca attgtatatt aggtttagtt
    23941 tcttcatcca taatttctgc aatctcttca atgtttttac cttgcattaa taaatttcct
    24001 acttctagtg cagaaatagt ggatatttgg tctataaata acattgggct atttatctta
    24061 ttctttaaat cttcatatat aagattaaga gagcccatat caaataacac aattaaacca
    24121 ttctttatcc tatctccttc taggtatcta gacatttgtt ttgatacatc agcaatagta
    24181 gcatctatag gcatatcaat agctgtaaat atatttttac ccaacatccg attacataca
    24241 ttcgccatac tactggcagt agcatatcca tgtgctataa tagtcgcatt aacttgatta
    24301 aatttcattc ttataattgt tgatttaata aatataatca ttatgattgt atctacatta
    24361 ttaagataca tatccaatct attcgttatt aatgttgata ttttacttat tatagagtat
    24421 tctttgtaac tctctttttt taaatatatt agtaatttat tttctaaagc tttatactca
    24481 tcagacaatt gataagattc gtccttcaaa taaagataag acgaaaatgc caatacatta
    24541 ttcccatcat attttatatt gttattaact tctaaatttc taaatatatc ctgcattatc
    24601 gatattataa gctccataag tacgttatta ttttcatcat tatttgaaaa gactaaattg
    24661 tccattagtc taatcattag attagaactc tttttactaa atttttcctt tgttatttca
    24721 tttttttcta gtctatcaaa gtaatctaaa cattttatga aactttgata gattatattt
    24781 cttttatttc ttccatttga catttcaata ctaaattgtt taggagaaaa gataatgctt
    24841 ttgcttttac cactttggaa ttgaaatata tctacatttt ctatataaag atttctagga
    24901 aggtcttgaa gagtaacaaa aatatttcca tttcttcttt gattttttgc ataagctcgt
    24961 ccacatgcat attttattac atttttacat tcacctatat tccccttgaa ttttatcttt
    25021 aaaatcgcat ttaatgtaat ttgagttatc tctataggca aaccaagtac cttactttct
    25081 tcataaataa aatgttctac aatctttctt ttttcaatag tccctctttc ttctatattg
    25141 ggaacataaa tatttatggg tattcttctt aaaaaggttt gtaaaaattc agatagactt
    25201 tctgttgtag caaatattaa tcttacccta gcttttctaa ttactccatt ctctccaatc
    25261 ctagaaaacg tacctgtatc cataaatgta aataactttt cctgaccttc actatttaat
    25321 ctatgtactt catctaaaaa taaaacacca ccatctgatt gttctattag acctgctcta
    25381 gattcatttg ctccagtata tgctcctttt acatgcccaa ataatagact agacaataac
    25441 tccaaattat tataatactg cgcacagttt aacacattgt atggagaatt tttttctaat
    25501 acattactgc ttacactata tttgtatatt atcttggcta aaaaagtttt tcctactcca
    25561 ctttcacctg tcagcattat tgtaagtccg ccatttggat aaagtacagc ggtttttatt
    25621 tgttcgatta cttcttttaa gctattctca tatcctatga tactattaaa cacagtctct
    25681 tgctttaata atttacactc atttttaagt tcatctaaat tttcataaat actttttttt
    25741 gtaggtccta ctacatcatt tattttattt ttaggtaaaa aaataacagg tctactgttt
    25801 atctttataa gattatcaga ttttactaaa tcatttaata atctacttga ttgagttcta
    25861 cttaaattaa acttttttac tatatcttct gttattatgc cactttcttt tttaagttca
    25921 tcaaagttgt taaataatac acattcattt acaaaactta aaatttcatc cctcatgttc
    25981 aacctccaat acaaatatca ataatactat aat
//
LOCUS       DAEQAF010000050        25903 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.052, whole genome shotgun sequence.
ACCESSION   DAEQAF010000050 DAEQAF010000000
VERSION     DAEQAF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25903
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.052"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(76..1164)
                     /locus_tag="KRN00_002210"
     CDS             complement(76..1164)
                     /locus_tag="KRN00_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828075.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            complement(1449..2147)
                     /locus_tag="KRN00_002211"
     CDS             complement(1449..2147)
                     /locus_tag="KRN00_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1828076.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            complement(2261..3766)
                     /locus_tag="KRN00_002212"
     CDS             complement(2261..3766)
                     /locus_tag="KRN00_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBH1828077.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            complement(4045..5316)
                     /gene="serS"
                     /locus_tag="KRN00_002213"
     CDS             complement(4045..5316)
                     /gene="serS"
                     /locus_tag="KRN00_002213"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH1828078.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVENKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGMDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            complement(6114..7718)
                     /locus_tag="KRN00_002214"
     CDS             complement(6114..7718)
                     /locus_tag="KRN00_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1828079.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNEIRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVVDNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAANQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDVKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMMETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDENPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            8104..9030
                     /locus_tag="KRN00_002215"
     CDS             8104..9030
                     /locus_tag="KRN00_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBH1828080.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            complement(9150..10148)
                     /locus_tag="KRN00_002216"
     CDS             complement(9150..10148)
                     /locus_tag="KRN00_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBH1828081.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            10252..10689
                     /locus_tag="KRN00_002217"
     CDS             10252..10689
                     /locus_tag="KRN00_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1828082.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRLLKKINDNFKNAD"
     gene            10775..11362
                     /locus_tag="KRN00_002218"
     CDS             10775..11362
                     /locus_tag="KRN00_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH1828083.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(11662..12282)
                     /locus_tag="KRN00_002219"
     CDS             complement(11662..12282)
                     /locus_tag="KRN00_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBH1828084.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEIDLTKEINDISIKLS"
     gene            complement(12290..13057)
                     /locus_tag="KRN00_002220"
     CDS             complement(12290..13057)
                     /locus_tag="KRN00_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBH1828085.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGAIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            complement(13098..13919)
                     /locus_tag="KRN00_002221"
     CDS             complement(13098..13919)
                     /locus_tag="KRN00_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828086.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     VNIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            complement(14278..16188)
                     /gene="phnW"
                     /locus_tag="KRN00_002222"
     CDS             complement(14278..16188)
                     /gene="phnW"
                     /locus_tag="KRN00_002222"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBH1828087.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     DYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSSISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYAQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            complement(16467..17252)
                     /locus_tag="KRN00_002223"
     CDS             complement(16467..17252)
                     /locus_tag="KRN00_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1828088.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPISIDTMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKEYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            complement(17469..17699)
                     /gene="dltC"
                     /locus_tag="KRN00_002224"
     CDS             complement(17469..17699)
                     /gene="dltC"
                     /locus_tag="KRN00_002224"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBH1828089.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            complement(17718..18866)
                     /gene="dltB"
                     /locus_tag="KRN00_002225"
     CDS             complement(17718..18866)
                     /gene="dltB"
                     /locus_tag="KRN00_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBH1828090.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            complement(18866..20380)
                     /locus_tag="KRN00_002226"
     CDS             complement(18866..20380)
                     /locus_tag="KRN00_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBH1828091.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVVYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDEKDFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            complement(20501..21691)
                     /gene="dltD"
                     /locus_tag="KRN00_002227"
     CDS             complement(20501..21691)
                     /gene="dltD"
                     /locus_tag="KRN00_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBH1828092.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            complement(21979..22998)
                     /locus_tag="KRN00_002228"
     CDS             complement(21979..22998)
                     /locus_tag="KRN00_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBH1828093.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSYENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            complement(23173..23712)
                     /locus_tag="KRN00_002229"
     CDS             complement(23173..23712)
                     /locus_tag="KRN00_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBH1828094.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            complement(23813..24493)
                     /locus_tag="KRN00_002230"
     CDS             complement(23813..24493)
                     /locus_tag="KRN00_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBH1828095.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTDIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PQNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILENLLEVREYLKSL
                     NSKECHNL"
     gene            complement(24522..25811)
                     /locus_tag="KRN00_002231"
     CDS             complement(24522..25811)
                     /locus_tag="KRN00_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBH1828096.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
BASE COUNT         8543 a         4444 c         2643 g        10273 t
ORIGIN      
        1 tatttaacta ttttgacttt ttaaattcgg attatataaa aaatttcttt aaataaaaac
       61 tattaataag tggctctatt cctgactttg tgttgatttt tttctacatg taattgcttt
      121 atacaccata cagactaaaa ttaaaagccc catataacct gtatatggat ataaaatgtt
      181 tactaattta ccaaacggta aaaaacctcc tatacaagcc aaaatagcta ttactgttgt
      241 taccaattta aatttaggat gttcatcttc aacaattcta ttggttacag accataaaag
      301 tggaacagct gttgtataga tacctaatat taatgcaact gaaaaacata cacctacaat
      361 cggagatata ttatctgcta aataaagtga tggtatttct ttcatataca aatttcctat
      421 atctgaaatc atagccaaat acataactat accagcagtc ataaacacta ttccacctaa
      481 taaacctccc caaaaagcat cctttttact ttcaatagaa gctcccattc ctgttaaaaa
      541 aacaatcatt acaataatat ttaatgtatt atatattaca ccagaaacga ttggactttc
      601 tgatgctttt gtaacttcaa tatttttcat agcttctcca accatagata aaccgtcaaa
      661 atgcttaaac aagcttatta atccaacagc aattgtaaat actgctatca ctggtccaat
      721 acgtccaagt atgcttacta atttttctaa acccatagac actgtaatta aagtagcaac
      781 agccatcaat actcttccta agtaaggatt tataccatag tattcagtta aagttgagcc
      841 tgcacctgaa atcattacta taagaatccc aaataaaaat attggactaa accattcgta
      901 aaattttcct aaaatcttcc cacaataaaa agtgtaaatt cttgttggtt ctttaagttt
      961 taattctcta cctctagtta taacttcagc accaagaaat gaaaacaata ccattgatat
     1021 taatgctcca attaaaccca tatacccttg tgaggcaaaa aattgtagaa tttcttgacc
     1081 agtagcaaac ccagaaccaa ttgctgttgc tagataagcg cctgcaatac agataatatt
     1141 tttcatattc actttgtctg acatattaaa ttacctccat tataaagtta ccttccttta
     1201 agaaatataa actctcagta aattaaatga aaattctgtc tttttgaaac agtatttaat
     1261 tcactttttt tattttgtat atctttttct ttttatttat atatattttt ttatataaat
     1321 aggtacagct tttataaggt ttaatattat taaatatgtt taaagcgctt taatttttat
     1381 cataattaaa gtatacttat tcagacacac tcaaacaatt atctatattg actttttatt
     1441 tatcaatttc aatttttagt gttcagttta taaacttttg gagtcattcc tttttctatc
     1501 ttaaagtttt tataaaagtt atttaggcta ttatatccaa ctatttctgc aatctcattt
     1561 atactttttg tagtattttc aagtaattca atagattttt ctattcttat atgatttaga
     1621 tatgatataa aagttgtatt taaattactt ttaaaaatcc tagatatatt agatggattg
     1681 gttaaaaata atctagcaca atcatttaac tttaagtcat tgctatagtt tagatttata
     1741 tattccagta tctcatttaa taaatcatta ttggtatatt gatatccaat aattttttct
     1801 acagacttag taaattcttt catatccaat ggtttaagga gtatatcttt tacatttaat
     1861 ctcaaagctt tttgagcata ttcaaaatag ttaaatgcag ttattactac aaagtttatt
     1921 tttttagata aatgagatgt tttttctatt acttctaacc cgttgtatat tggcatttga
     1981 atatctataa aaactatgtc tggctctaaa ccaatgattt tatctactgc ttcatcacca
     2041 gatgttgctt taccaacaat ttttattggc atatctttca tttctataaa atgtgttatt
     2101 atttttagaa cagcttcttc atcatctatt attagtgctc ttctcatgag aatacctccc
     2161 ttttagctta ataatataaa aaagtaagat atataaaaca acataaaaac atctaatata
     2221 tttcttaaca tttataaaac ttattaattt ttcacaagtt ctatacatat tccttataat
     2281 tttcaatagg aattttaatc attatgtaag ttccttcatt atcactcgac tttatatcca
     2341 tatcaaaatt atttccataa gcagatgtga attttgtata tattaaagac aaaccatgac
     2401 cattattact acgaatacct gcctttattt tgtctatatt atttccatct aagatagttc
     2461 cattattatg aatctctata atagcatact gagaatctaa tcttgcaatt atttcaattc
     2521 gcttttctgt gtcaatatct ctaaatccat gtgtaaatgc attctctaca ataggttgaa
     2581 taaagttaaa aggcacagaa aggttatata acttctctgg aataagatat tttactttaa
     2641 gtgcatctcc ataacgtaat ttctgtaaat tcaaataatt tttaatgtat aatatttcag
     2701 attctaattc tacaaatctt aaatcagacc tcattgtata tctaaacatt cttgataaat
     2761 ctattattgc actatacaaa tcataactac catcatctag tgctatgctt gccattgaat
     2821 ttaatgtatt aaataaaaag tgatgattta ttcttaaatt agtaaccata tcttgagcta
     2881 cttttaaatt catttcaagt tgctctccat aatgatatgt tcttgctata gtcttctctt
     2941 tttcttgtaa atcctttctt atatcattaa aagagcaaaa atttattata tttttagata
     3001 tttgtttcaa gaggcgtttt atacttctag cagctccctc tggaatatca tataaattat
     3061 tatgctctgt atctaaattc aaatcagata atagtacata ccctcctctt ataacaccta
     3121 tgctattgct tttgtacagt attggtatat tatatatagt tatcccatat tcacatacaa
     3181 attgattgct acttttttga ttcatacaat cacaattttg aggaaatttc ataggattac
     3241 atttttcaaa acaaaaaagt ggaaaataag gattttttaa aactatattc catgaatcat
     3301 catatataat taatggaatt ttaaacgggt ctataaattg accacgaatt gattctactg
     3361 ctgcatacaa atttaatgta ctttcactat aatttatcaa ggtcttcttt aaataattat
     3421 taggattaat atctataact tcactctctc ctacatcatc tacattattt gaaacaataa
     3481 gttcttttat ttctctatcg cctgtattta tagtttcatg tgtgctacca gattctatat
     3541 aaaaaatcat accttgataa aatggcttcc aaactccatt tataatatac aaaccctctc
     3601 cctctaaaat atatatcatc tgctcttgac cataatgaac atgattaaaa tgtttcttac
     3661 caggcatagt tactgcaatg tatatattca tagcttgttt tggattattt tcatcataag
     3721 tatgtttcca ttcaatatat ccccactcag tattttgaat tttcataaaa gattcctttc
     3781 ctgtaaatta tttatgttca tattgtgaaa aattagtaaa aaaaatgtgt acatactctt
     3841 tcatatgata gcttactata tcaatattca ttagtttgta cacattttta tattaattat
     3901 tttttttatt acttctatta ttattgtatc acttttatat taactatttt tttattactt
     3961 ctatattaga agtatcactt ttatattaat tattttttat tacctctata ttattgtatt
     4021 gcttaaaaat acataattta actcttattt aataacagaa actcccatat atggtcttaa
     4081 aacttcagga acaaccacag aaccatcttc ttgttgataa ttttctaata tagctgcaac
     4141 acttcttcca atagctaacc cagagccatt taatgtgtgt acatattcag ctttagaatc
     4201 tttatctctt ttaaatctta ttcctgctct tctagcttgg aaatcttcgc agtttgaaca
     4261 agatgaaatc tcaacatacc tattgtaact tggcatccaa acttctacat catatttaaa
     4321 agaagccgta aatcctaaat cacctgtaca tatctttact accctataag gcagattcaa
     4381 taattgtagc atagtttccg cattgttagt aagcttttct aactcattgt aagattcttc
     4441 tggtgcaact attttaacca tttctacttt gttaaactga tgctgtctta ctaaacctct
     4501 tgtatctctt ccagcagaac cagcttctga cctaaaacat ggagtataag ctgtataatt
     4561 tatcggtaat tgttcaaatt taagtatttc attagcatgt atattagtta aaggaacttc
     4621 tgatgttgga atcataaaat agtccatacc ttctatttta aacatatctt cttcaaactt
     4681 aggtaactgt cctgtaccta aaaaactatt tctatttgcc ataaatggtg gaataacttc
     4741 tgtatatcca tttacttttg tattcgtgtc taagtaaaaa tttaataatg ctctctctaa
     4801 tctagcacct aatcctttgt aaagagtaaa tcttgaacca gttattttac tagctgtttc
     4861 aaaatcaagt atacctaatt ctgttccaat ttcccaatga gccttagatt caaaatcaaa
     4921 ggtagtagtc tttccccaag ttcttacttc aacattatct tcatcagttt caccttgtgg
     4981 tacttctgga tgtggtacat ttggtattct cattaatagg tattccatct tattttctac
     5041 ttctttaaga ttttggtcta ttaccttaat tttatcagat aactctttta gtttaatctt
     5101 ttcattttct acatctttac cttcttttat aagatttggt atatttttag atgctgtatt
     5161 taattcattt ttcataactt caacttcttg aagaatcttt cttctttcat catctaactt
     5221 aactacttca tcaaggttaa agtctttttc gccccttctt tccattgctt tttttataca
     5281 atctaaattt tctcttattc tttttatatc aagcattttt tcctcctcag tacctaagat
     5341 tggatttatc tcttaatctc aaataactta gataatatac ttcatgcttg aggttaagaa
     5401 acctttttct ttatccgaac ctgttatttt tattttattt atattttact cacttttttg
     5461 cccattgtca aattatattt aattaaataa atgaaattta attttaggag aatgttgcta
     5521 gatttaactt cattataatt atatctattt tgctaatcaa ttatctattt tgactttttc
     5581 tttatcaatc ttgtatagtt attaactttt atataaattt ttttatatta taacatagtc
     5641 ctatatatct attatttgga tagaattatt ttgatgaatg attcaagtaa taggtatgaa
     5701 attgaatctt ttagaactgc ttacaaaaaa tactcaaaga aaaatagtaa ttttctcaga
     5761 ttcacaatat attttatatg aaatgttata aggtaatcta tttaataaat ttaaatttgc
     5821 tattatagat ttagttccaa agtcttactg caaagtaata tacatagttt tttaataaac
     5881 taataagttc aattaataac tacttaattg tttaatatag tacatagata actttaataa
     5941 atcgacagtt atttaaaaag gtagaatcaa taaaattata cttataaatc ttcaatacaa
     6001 taattaaaat ttaataaaaa tataattgtt gatttaactg taatcttatt taattctacc
     6061 taacttatta tataaaacta ttttttatag attataaaat atctaacttt catctacttc
     6121 aaagaataca atacttcccc ttctcttata gtctgcaata ctttaatatc ttttattttc
     6181 atagggtcga ttgtaagtgg gttttcatct aatattatca aattagctaa tttcccttct
     6241 ttaattgaac cttttttatc ttcttcaaaa tattgatatg ctgcatttat agtaacaccc
     6301 tttaaagcat ctaatgggct tatcttttca ttttctccta tttgtatacc tttttttgta
     6361 attctattga cagcacacca tactgtttcc atcatattag gtgctattac tggtgtatcc
     6421 tgatgaagag tgtaaattaa tcccttttct atagttgttt taagtgggct aatcttaaac
     6481 gctctatctt ctccaaggtt tttgatatga atatcacccc aataatatgt gtgagctaca
     6541 aagtatgaag gtatcatatt tattactttc acatcatcaa tctggtctgc tcttactgtt
     6601 tgagcatgta tcataactgg tcttatatta ttttcactac tttgctcttt taagtttaaa
     6661 actttctcaa acgcatctat caactggttt gctgctgcat ctccattaca atgagttaag
     6721 agttgcatct tttcttttag tgaaatatct ataaactttt ctacttcttc atctttgtat
     6781 ataggatatc cacaataacc atcatctgaa ttttcatatg gtctactcaa ccatgctgtc
     6841 ttaccttgag gagaaccatc taagaaaatc ttataacctc ctattttaaa tctatttata
     6901 tattttttta taaactccct attattatct actacagact tacttttttt caaatttaca
     6961 tatcctacaa catccatttt taatttattt tgatttgcca ttgcttttaa aatgttaaat
     7021 tgattttctt ccattaaacc ttcttgagct gttgtaatac catagcttag atatatgttc
     7081 tgtgcttttt caattgaatt aaaaatctca tttgatgatg gttgttttat tttagatgct
     7141 acattaaaaa atgcattttc ttctaaatat ccatttggtt cttcactgcc ttctactcta
     7201 cctatatgtc caccttctgg gtcacgtatt tcattggtaa caccaagctg ttttaacccc
     7261 aatgtatttg caactcccat atgaccagaa gcatgtgaaa ttagtattgg attttctgaa
     7321 gatgcactat cgagtacact cttatctgga tgcttatttt cttctaaaaa attattatca
     7381 tatgaaaatc caattatcca gtctcctttt tttatattat tcgactcttt gaaatcctgt
     7441 atttttttta ctatgtcttt aaaactggtt gcatcttcta aaggaactag ctttagagta
     7501 gtagcaaaag ctatcaagtg actatgtgaa tctataaaag atggcatcaa tgtcttacct
     7561 tgtaaatcta taatttctgt atctttattt ttcaaagcaa atacttcttc ttttgttcct
     7621 atctttttta ttattttgtc ttttataaga atagcatctc cacatattga atcttccatt
     7681 gtgatgatat ttccattgta ataaattttt gctttcataa aattctcctt acgttgtcta
     7741 ctttaataaa tttttttcat tattttctgc ttaattatat tatcttcttt ataaactttt
     7801 tctttagagt ttaatcatat aaaagtttta tttttaatta ttgtttgcca agaagtaaat
     7861 actattcatt gtaaataaga caaattaata ggatttatac taattgaaaa aatattataa
     7921 gttgttaaat ttaaatatct aaactcaatt atatctgtac aattgtaatt ttttaaatca
     7981 tgatgtatta ttttaaatat acagttacat tattattcac aatataagta tcttagttct
     8041 caaataacat ctcatgtaat ctattcaatg caaaaaattt aaatattttt taggaggttt
     8101 tttatgagca aggaaaataa aaatgtaaga attgctgttg tccaggcgtc accagtcata
     8161 atggatttag aaaaaactgt tgaaaaagca ttaggattaa ttaaagaagc tggtagaaaa
     8221 ggggcaaata tcgtagtttt ccctgaagca ttcatacctg catatccaag aggtctttca
     8281 tttggatttg ttgttggaag tagaacaatg gaaggtagag aagattggaa aagatactat
     8341 gataattctg taccagttcc tagtgctaca acagatttat taggaaaagc agcacaagaa
     8401 gcaggagtat atctatcaat gggtataaca gaaagagatg gtaatgatat aaattgtacc
     8461 ctttattgca caaacttatt tttctctcca gaaggtaagc taattggtaa acacagaaaa
     8521 cttaaaccta caggaacaga aagatgtatt tggggagaag gagatggaag tactcttaca
     8581 gtagttgata ctccatatgg aaaaatgggt tcgttgattt gttgggaaaa ttatatgcca
     8641 ttagctagaa cagctcttta tgctaagggt gtaaaacttt acatagcccc tactgcagat
     8701 tcaagagaag agtggcaagc aactatgaaa catattgctt tagaaggaag atgttttgta
     8761 attggatgca atcaatatgt tgaaaaaaat atgtatccaa ctgaccttaa ctactataaa
     8821 gagctagatg cagaaccaga aattatgtgt ccaggaggaa gttgtatagt tgaccctttt
     8881 ggaaaatatg tagcaggtcc tattttcaat aaagaagaaa tgctaatagc tgatttagac
     8941 ctagaaaaaa tagtacttag tagactagat tttgattcag aaggtcacta ttcaagacca
     9001 gatgtatttg aattaattgt tcatgaataa tctttttaca caaacatcta cataaatctt
     9061 tttacataaa aaaatgagat actcataagt aaatttcaag tatctcattt ttgcttaaaa
     9121 cctataatcc taattataaa tttattcacc tatatttttt ctaaatcaac tactgttctt
     9181 ccaacatgtt ttcctgccat tattgaatct atactatcat ttaactcttc caatgatact
     9241 acatttacca tatcatctaa atcatctaat ttccattcat ttgataataa atcccatatt
     9301 tttaatctta agttcattgg gcaatccaca gaatctatac catataaagt aattcccttt
     9361 aatataaatg gatatactga acttgtaaaa tcaactcctc ctgcattacc acaagttgtt
     9421 actgctccac aataattagt tgtctttatt gctgttgcta gagtatttcc tcctactgta
     9481 tctattactc cagcccatct tggtctaagc agaggtcttc ctgagttatc atccacttct
     9541 gacctatgta taacatcttt aacacctaag tttagtaata cttctttttg ttcttctaat
     9601 tttcctgttg aaactacaac tgaataacct aatttaatca atattttagt tgcaattaca
     9661 gcaactcctc cagtaccacc agtgactaat acatctccca tattcttgtc tacagaatct
     9721 ataaatttat acacagataa agctgctgta aaccctgctg taccataatc cattgcttct
     9781 tttagtgaaa gatttttagg aagtttaact acccaactag aaggaactct tatgtattct
     9841 gaaaaaccac cagaagtatt cattcccaag tcataacctg ttactaaaac ttcttctcca
     9901 attttaaaat catcacaact actagattct actataccag atgcatcaat tcctggtgta
     9961 tgaggatact ttctcgtaac acccttatta ccatttgcag aaagtgcatc cttgtaattt
    10021 aaagaagaat attttacttt tattaaaact tcgccttctg gcaatgtatc cacttctctt
    10081 tcaactatat ttcttctaaa atttccttct tcttctgtaa tatatagtga tttaaatttt
    10141 ttattcataa atttcctccc aatacattta gttttatgtt aaactaatta tagtttataa
    10201 atagttttat gtcaaactaa tttaaataga ttaaagattg gagaataatt tatggaagat
    10261 aaatatattg tacatttcat aagtaaaaca aaggctagta tgattaaatt cattgaaaat
    10321 aaactcagta aaaatggttt aggtgagtta atacctactc atggaaatat tttaactgca
    10381 ctttatgaaa ataatggaat acttacaatg aaagaaattg cagctaaaat aggaaaagat
    10441 aaatccactg ttacagtgtt ggttaataaa cttataaacc taggatattt agaaagacaa
    10501 aaatgtacaa atgacaaacg tatcacgtat ataaagctta caaaaaaggc actgcttata
    10561 gaagatactt ttaatagcat ctcaacacaa gttaaagaga cagcatacca taatattaca
    10621 gaaaatgaaa aacaagaatt tcttagactt ttaaaaaaaa ttaatgataa ttttaaaaat
    10681 gctgactaaa ttgagcataa ttatatctcc tattggaata ataaataaaa agaatcaaat
    10741 attgtaaaaa tttattgtga tagagaggta gaatatgaat ttaaaagata gtaaaactaa
    10801 agaaaattta ttaagagctt ttgcaggtga gagtcaagct agaaatagat acaatatttc
    10861 tgcatctgta gcaaaaaaag aaggattata tataatagag tctttattta attacactgc
    10921 tgaccaagaa aaatcacatg caaaacaatt cttttctaaa ttaaaagaat ttgctggtga
    10981 aaatataagt atatcaggag cataccctgt agatttatat gacaagacag cacaacacct
    11041 taaagctgca caacataatg agcttcaaga gtgggatgat gtatataaaa actttggaaa
    11101 aacagcacgt gaagaaggat ttgaatctat agctaagtta tttgaaaata tagctgaaat
    11161 agaaaaagtt catggtgata gatttggtag atatgctact gatttagaag aaggtacttt
    11221 attcagaaga aatgaagata tacaatggat atgtacacat tgtggccata tacatatagg
    11281 taaagaagct ccaaaagctt gtcctgtatg tcttcatcca caaggatatt tcttagattt
    11341 taaaaactca ttatttgaat aaattaaggc aataattcta tttaaacaat ttactatatt
    11401 tatatcaagt atttttataa atactgtatt atcttaataa caataaaatg aaccattgat
    11461 attactataa gtagaaaatg tagtttaaat acaatttatg gtagttcatc atggttcatt
    11521 ttattgttta ctaatcccta taacctactt aaatctatct ttaactttta cacactcaca
    11581 taaaatctca tctttaaact aaatatttaa ataaagtgta ttttaagtag attattataa
    11641 tacattatat aagataatac actatgataa ctttatactt atatcattta tttcttttgt
    11701 caagtcaatc tcaataatct taactacatc tttttcaaac tttacttttt tataatccag
    11761 acatcctact acgaatggaa ctccaaactt tctaaacaaa taaatcttcc cactttcatt
    11821 gtatattgat gtaaaatttt cttctattat attcactatc aattttaact cttcaaaagt
    11881 tattatagat ttaactaaaa acttctctat tatgctcaat ataagcagtt cttttttacc
    11941 tatgctttgc tcttttttat ataaattttg aaatatttct ttggtataat tacatataac
    12001 ttctttactg agaataaaat caatgtcaaa ttctttatta atatcctttt tcataaacat
    12061 atttgcaata tcatcaagag aagtctcttc tttcatagac aatattaact ctattctttc
    12121 tagtatttta tctcttggaa agaaagtctc ttgacctgta aaagctgatt tttttataaa
    12181 ccattcctct ggtattatgt tttttctttt ccatctatat aattgaccat aagatatatt
    12241 agttttgctc aataaatctt tcttagatat taattcttcc ataacttttc tagcccacct
    12301 ttatactgtt ttttacagta gaattatctg aaactgataa attatcactg tattcaatat
    12361 ttccaacatc acaattatct actagagata tgcttttacc tcgtatatct tttattgatg
    12421 catcttctaa ttcaatagta tctccctcta tcaaattaca tttaaacttt cctgaaaaaa
    12481 tattaatgat tttaattaat gaaaaagcat ctttgcttct tcctattttt atattagttg
    12541 cccctatctc tttacaataa gaacctcctc ctgaataaac atatatattt tctccattta
    12601 aaagaccatc acattttatt gctccatata cctttatatc ttcacattct atatttgatt
    12661 tatttctcat ttcgccatag atttttatat cttgtgcata catattttca tttacactta
    12721 attgtcctct tattgtaaca ttattacatt taagtttgcc atccactttc tgttgagcag
    12781 ttataactaa gtcatctatt tctgcatctc cctctatatt aagttgacca ttcactctta
    12841 cacgctctgc tttaagattg cctcttataa tagtttttcc gttaacaaca aaatttttta
    12901 tattgatgtc accttcaaat tttgcatctc caaggacttt tacttcgtta cttttaacat
    12961 ttccttttga tttagaactt cccacaattt ttatattttc atactcacca ctacttataa
    13021 agccttctcc aagtattttt atagaccctt tttccatatt attacctcat tttaaatttt
    13081 atttttaaac ctacttatta cttatccttc tttaatttta ttttttcact tatattcttt
    13141 atttcaccaa ctattgaatc ttcatcaatc tctatacttt cactgtactc caaactttct
    13201 acataacatc ccttgcctat tttaatattt tttcctctta caactttgac ttcactattt
    13261 tctaagctta tttcatctgc ttctataata tttgcaaaca atttactttc tgtatacttt
    13321 ctaattgata atagacctaa acttattaaa tttgaagaca ctttttcaaa gttgatatgc
    13381 tttttttcta gcatacgaaa ttttttgcaa taatctccat gccccttttt tatatttaca
    13441 ctacttgctc caacttcatt aaaattagaa gttccattta aactaatatt aacttcttca
    13501 caattcaaaa atccattaca ctccaagatt ccacttaaat tgatattttc acaatctata
    13561 ttctcatttg cttttaaata tccttctcca tgaataatat ccgattttat acttccttct
    13621 acattaataa ttccactagt atcaatttca acagaattaa tatttcctgt acatctaaga
    13681 agtcccgata tctcaacttt tgatgccagt atgtttcctt ctactttact taaaccagat
    13741 gtaaaaaatt cattacattc tgttgtccca aaaacttttg ctgaaccaga agaatcaaat
    13801 ttactacatt ttacacttcc ttctattttg cctgttcctg atatattaac attatcaaaa
    13861 attccacctt tacattttcc aacaccatca aatcttagtg aacttaattc ttcattcata
    13921 atgatatcct ttctttaccg tattttatct ttaaacctaa tataacaaaa cattgttacg
    13981 ttgtcaagta tgataataat acttaataaa gcaactatca tttattttct ataaataggc
    14041 ataaaaataa tagggaaatt ctttatttaa actataaatc taatttctta gattgtggtt
    14101 taaataaaat atatccctat tactcaatgt ttatatattc attgtataaa cttctaaaat
    14161 ataagtcttt aaattctact gtcaatactt tttatacact gtttgtgcta tcatctcaca
    14221 cacctaaagg agtgggcttt ccacactatt ctgtaaccta caagacacta tcttcttcta
    14281 tctattgata aatttttcta ttacatcagc tagtctctcc atatcagttg gataaacttc
    14341 acctatgcta cctattctaa atgtatctat atcagtcaat ttacctggat agataacaaa
    14401 tccattatct tttaaataag tataaaattc cataaattca aactttgcat ttttaggata
    14461 taagaaagtt gttattacag gtgattgagc attatcattc accaaagtat caaatcctaa
    14521 agattttaat cttgaagcta ttgtaaactg attttcttta tatctagcat atcttttttc
    14581 aacagaacct tcttcttcca attctaataa agcttgataa aaagctctta caacatgtgt
    14641 aggtgaggta aatctccatt taccattatt tttctccata gtctcccatt gcgcatacac
    14701 atcaagagat aatgatttag ctataccttt acatttagat aatttctctt tattagctat
    14761 tataaaacca aatccaggta ctccttgtat acatttgtta gaactactaa ctaaaaaatc
    14821 tatattaaaa tcttcaacat caatctcaat tcccccaaaa ctactcatag catcaactat
    14881 ataaattttg ttatattctt ttgcaagttt ccctacctct tgtataggat ttaatctacc
    14941 tgtagtagtt tcacagtgaa ccattgatat atgtgttata tccttgtttt cttttaataa
    15001 attttctact acatttaaat ccactgcttc tatatcttta aatgtgcaat caacaaattc
    15061 tatgttaaga taattacata tatctttcat tctctttcca tatgctccat ttgcaattac
    15121 aagaagttta ccatcttttg aaatagaact tcctattata gcttctactg aaaaagtccc
    15181 acttccttgc attaatacac ttgtgtattt atctgtattt tgggttgcta gagatactaa
    15241 tcttcttcta acatcttgta ctaagttatt atattcaaca tcccaagtac accaatcttt
    15301 taacatagat gctcttactg atttagtagt agatagtggt cctggtgtaa gtaatatgta
    15361 atcattttct ggtacaaaat ctgatttaat agtttcattc tctattttta ttagtatatc
    15421 ttctaactca gccatagttt ctattacaaa atgtgctcct gcctctttaa atttctttga
    15481 aactatactc atcttagctt ttaattcttc cttatccatg ttctctactt cttcttgtgt
    15541 aagccctaac tcacttgaac cttttattac agcaacactc cacattcctg catttacgcc
    15601 ttcttttaca tcacttattg tatctcctac ttttaccata gaactcatag gagacacccc
    15661 taaagcttca gcatttttat agcacatcca aggatacggt cttccttgag atacttctga
    15721 tggtgttaca agaaaatcgg gtgagtatcc cttctttgct gcatttggtt caactatgtt
    15781 catcatctct cttgtataac ccgttgtaga acctattttt aatccatttt ttctcaactt
    15841 ttcaatagtt tcaacaacat gaggaattgg agtcgtataa tcttctaatg tctcaaataa
    15901 cattggctca aattcagcat aaagttcatt tacatcatct tcagttggca ctttaccaaa
    15961 tttatctgac caaatattct ttattctatc catttcacac atttctctta tatggtctat
    16021 ttttaatttt cccataggtt ttcttgcttc ttccattgtt acatctatac ctcttctttt
    16081 aaatatctct ataaatacat taagaggtgc aaaacatcca taatctactg ttgttccagc
    16141 ccaatcgaat actactgctt ttattttttc tccatatatc tttttcatat ttatagcctc
    16201 catagattct ttttagaatt tttgtgtttt taattgtttt tacttttaaa gtataacttt
    16261 catatgttaa ttatacatca tatttaggtt aaatatatat taaatttctg tttttagttg
    16321 tatttaattg tttttatttt gtatcatatt cccataaaat cctaagttac aatctaaaat
    16381 ttactttcta atcttaatct atgaactgac tatattttat gaatttagtt gtattgagca
    16441 tagttgtatt atataaaact aagggtttat tttgcttcta tccatgttat atttatctca
    16501 tttaacttat ccttccattc attcggaggt tctacatcac aaataacaaa atctaattcc
    16561 tctaaatctg cgatcttata catactagca attcctattt tagaactatc acataataca
    16621 aaactttcct ttgaattttt tatatattct tttgacaaca atgccttatt ttggtctata
    16681 ctactaattc caaaactatc aagtatacct tcactagata taaaagcttt atctacgtat
    16741 aagtttttca tagtatctat tgatattgga catgctgtcc tttggtgttt taaatttact
    16801 tttccaccaa taaatataac ttctccatca aacaaacctt gattctcata agaaatcaat
    16861 tttgatagaa ctggataaga gtttgtaata atttttaaat tgtttacaga tattatataa
    16921 tctacaatct gcaaattggt agtaccttca tctatgataa ttgactcatt gtcatttaca
    16981 aacttagctg catatttagc aatactttgc tttttatcta ggttagtatt gtttctcttt
    17041 atatgttctg gttcaatcac tccataattt atttttatag caccaccata tacctttttt
    17101 aatttatttt cattttctaa ttcttccaaa tatcttctta ttgtttctga tgatacttct
    17161 aatcttttta ctaattcttt agtgtttacc ttcccttttg aatctaataa tttaagtatt
    17221 tctttttttc tatctatcga atttaaagac attcattttc ctcctaaata taatatattt
    17281 ttctcctata atattacaat gatacctaag atttatgaaa tcatatttat gtattaaatt
    17341 ttttacttaa ttaaagttat tttcaaaaga ctttgtatta tcattaaaaa agtccatcaa
    17401 atattagtat cagatggact ttgtaaaatt ttattttata aattaatatt taaagtctaa
    17461 ctactaattt attttcttgt ctccaagaat tttactaaat tatttacagt agacatatct
    17521 tttctctcta aatcagttgg ttgaagctct atccctaatc tattttcaat ttcaagtaaa
    17581 acttcaatta tagctaatga gtctaaaagt tccgtctcaa ataaattaag gtctaaatct
    17641 tctcttatct catcagttcc taatacatct tcaaatattt ctataactgt ttcttgcata
    17701 aattttcctc cttaaaatta agctaaataa cctgagaata tcagcaatcc aaaacacaca
    17761 atatggaatg taatgaaaat ctgcactctc tcgaaccatt tatctttttt atgtttttta
    17821 taaaatttag attttcgctg atatatatca gttaacacaa gtgccaatcc ttggtataca
    17881 ccataagcaa cataatacca agttagacca tgccaaaatc ccattgttat catggttatc
    17941 atctgagcca catgagcagc agtagtcctt ttcttaaatc ttttctttct cattgatgac
    18001 ataacaaatc tagaaaaaat ataatctcca aaccatcttg aaagacttat atgccatctt
    18061 gtccagaact ctttcatatc tttgctgata aatggcttgt caaagtttat aggtacttgt
    18121 attccaaata tgtaccctgt acctatagca aataaactat atcccgcaaa atcaaagaac
    18181 aggtataaac tatatgcgta catataactt aaaatattta taaaactcat atctttaggt
    18241 attcttgata cccaatatgt atttatcaaa aatgctataa caaacttata acctactccc
    18301 atgacaatat tttttattcc tggcagtaag tattcttcta tatactcttt tctagagatt
    18361 tgtttttcca agtcctgttc aaatcttctt gacctatcaa taggtccaga acttaaagtt
    18421 ggaaaaaata acataaaata aagcatcttt gaaattttaa cttcttttat agctccatca
    18481 taaatttcaa taaccatttg tatagttctg aaatttaagt atgatattcc aataaatcca
    18541 attattccaa aagaagtaac tggagatatt ttatttatta ttattgggag cattgatgca
    18601 aacaagaatc cccaatatat gtatttattt ttagtttttc ttcttacata ttcatatcct
    18661 ttaactatta ttacttcaag aataataaat attaccaagt actttagttg gacatcaatt
    18721 cctactatta agaatatcat aaacaaactt gccaacatac cataatactt tatattcttg
    18781 cccattagac ctaaaattac tgctggtatt gatgttaata ataatatata aagataaaaa
    18841 taatctccat attgtgaaaa aatcattaaa tttcctccat aagtttcttt ctgtctattt
    18901 taccattgat atttgttgga aactcagaga ttattgaaat atttcttgga atcatatatg
    18961 aaggtatata ctttccaagt tcctttttta ttatcatccc atttttaata ttacttaaat
    19021 cattcttttc atttaactca acaatacctt ttaagtaagc aattttttcg tccttataca
    19081 ctggtaaaac tactgcattt tttacattat gtacttttct caaattattt tctatatctt
    19141 ctatttcaat tctaaatcca tttaatttaa tctgaaaatc ttttcttcca caataatata
    19201 tatttccatc taaaagatat cccatatctc cagttttata agctctccac tttacaccat
    19261 ctatttcatc atagaaaaat acttcatcag tcttttcttt attattgaag taacctttag
    19321 aaactgatgg tccaattatt ataatttcac ccttttcatt ttctttaagc tcatttccat
    19381 cttcatcaag tatttttatt ttacaatttg acatagggta tccaactgga agactttttt
    19441 catcatctat agccttttga gtcatatcat ttacacttac accaacagta gcctcggttg
    19501 gtccatatcc attgataatt cttgtgtttg gaaatctact cataagttct ttagtaagat
    19561 tttttgaaag tgcttctcct atgaatatca ttgactcaag gttaggaagc attttactat
    19621 taaactcttt ttcagttata catactcctg caaaagaagg agttgacacc catacagcta
    19681 tatctgagat actaaattgt ctaaatagtt ctttatagtc tgctaataca tcttttgata
    19741 ttgaaaataa tgtagctcca tggataagac cagggtatat tgttgtaact gaaaggtcaa
    19801 aagaatatgc tggttggttc attattactt tttcacttcc atctatgttt agatatgggc
    19861 ttatccaatc tgaaaagcta tctaaattgt ttgaacttat ttgaacccct tttggctttc
    19921 ctgtacttcc tgaagtaaat agtatatatg cattttcatc atcttttacc cagttttctt
    19981 tatctaatga ttttccctga tattcattta ttatataatt taatttatcc atatcaatta
    20041 cattgatatc tccaaaatct ttttcatcac taaagttaaa taataccttt ggttttatct
    20101 ctttagtgac ttcaaaaact ctatcaattg gaaaactaat atcaagaggc acatacgctc
    20161 tacctgattt taaagctcct atcatacatg ccattatcat gttttcttta tttccataaa
    20221 ctactatagg agtatcttct tctttgtata catcctttag aaatactgat atagcatctg
    20281 aatattcatt taaatcttta taagaaagtt tatctccatt acacattagt gctgttctat
    20341 ctgtatttga atattttttt attccttcaa taattttcat ataagaatgc tcctttaaaa
    20401 tccgttataa ataaatggca attctttaaa tggagtaaat gttagaactc ctatcgccaa
    20461 tattataacc atagttaaac aaatactagt taacaaatct ttattgttct ttaaatattt
    20521 taaataatct ctcacagaca tctacccatc ctttcgtacc aagatgcatt acatccctta
    20581 aataatactt atctgaccct ttatctttaa ggtttagaac ttcaaagcct ttgctttctg
    20641 ctattttttg tgctttatcg tagtactgat ttctttcttt ttcagaaata ccagtcaaat
    20701 tatagaattt atccatactt gggattaata caacaactgg cttaatacct aagtcagtac
    20761 atacatttag catcagttta taattttcaa actccttaga tgttaataaa tttacatctt
    20821 tgtctcttcc tttgtattgc tctataccat ctttaaaatg ctctttataa tagtacttat
    20881 caatatttag tggattttta ccaactcttt ttttagcatc ttcaatggct ttctttctct
    20941 catatgacca atttattggt ctttttcttt ttgttgctct ctttttatct agcttaatta
    21001 atcgtttata aagaataccc ttttctttaa gagctataca atactttctt ccttgaaaat
    21061 aaggctctaa aagcaccttt tcagcttttt caggaaatgt cttaggctca tatagcttag
    21121 catataatgc ttctgcttta tactcgtcac ttccccataa taacttactt gatttttttg
    21181 catattcaat cttattttgt ttagatattt ttggattatc taaaaatcga taaaattgta
    21241 ttggtgaaaa tctagactga taatggtgac ttgtgactcc gtctttttcc ataaaccatt
    21301 gcatagaaat taacaagaca actttcttat tatcaatatt aggattcata cttcctaata
    21361 ttgcagcatc ttgtaatgtc tgagtatagg ctctcccaat tgcaaacacc ttatttttac
    21421 tcctatttgt attaaaatag tactttggat gttgttttgt tgaattacta agttctgatg
    21481 accccaaaat cataatatcc ttttctctta aaaaatgatt atttgctgta acccctttat
    21541 cttttatatc acttaaagta tcatccataa ttggaagtag atttttctcc ctcaaaagtt
    21601 catcagtttt agaatcaaga aatttgtcta acccaaataa aaatactacg cctattataa
    21661 aaggtgtaat aaagtatatc aattttctca tattttctct cctctaaaaa tattcaaatt
    21721 tatgttatta ttaatcatat tagttttgat atgtatattc aactacaaaa ttgtaataaa
    21781 atcgtcaaaa ctttttttga tactgttaca aaattgtaaa aaaaaagaaa aaaacgccaa
    21841 aaataaattt ctttttagca ctttttcata cttataattt gacattttaa cacttggcta
    21901 agtatacacc ttaccttaac ttaaaattaa atttatttaa gaatatatat tataaattct
    21961 tatattttct aatataaact atatactatc agctggataa acaatactac tttgtcttct
    22021 tatctcatcc ataatttcca ttactattat tgaattttca taagaattta tatttgattc
    22081 tattttattg ttatttataa gacttataaa ctctacaagt tcataataca ttccttctat
    22141 ttctctaggc ttttcctctg ctttttcttt tggaatagat atatcttctt ctcttccatc
    22201 tctgtattta ataatagctt tttcaaatag attaagcttt tcaattatta tacttccctc
    22261 ttctccttgt atttcagatg gtatataaga atcagctact ttagaatact gaattatcgc
    22321 atccatatca tcatattgaa atacagctga accttctcca tccactccag tttgaagtat
    22381 atgagaaact gcctttacag tttttggagc accaaataaa ttcaccatag gatgtataca
    22441 atacactcct atatccatta aagctccatt tgacaactct tttttaaagg cattttctat
    22501 aattccattt ttatatttat catatcttga agaatactga caatagcttc caaaaaatct
    22561 tcttattttc cctattttat ataagttttc tttaactgct ttaaagtttg gaacacatgt
    22621 aattctcata gcttccataa gcaatacatt attatctttg gctgttttta tcattgattt
    22681 gacttctttt aaattagatg ctaacgactt ttcacaaagc acatgttttt tgtgttttaa
    22741 acaagtaatg gtttgctttg aatgtaatgc atttggagaa gctatgtata cagcatctat
    22801 atccttcgat ttagccattt gttctaaatc atcaaaaaaa atacttgctc catatagagt
    22861 tccaaattct ctagcttttt ctaaatttct agaatataca gcaaccaatt caaagtcttt
    22921 aaccctagat gcagctctta gaaatatatt tgctatattg cttgtcccaa caatgccaaa
    22981 tcttatttta cccatcataa atcactcccc attttctaca ctttatttta atttaataaa
    23041 aaactttaca acttatagat atattataaa ataattttat caaataaaaa agaaagctaa
    23101 ttttaaatga tttcaccatt ttaacatagc tttcttttaa ctacaatcta aattcaactt
    23161 atatttttaa agttatcttt ctactatatc tttatttccc ctcaaaaatt ttatagtaag
    23221 aatttcatcc acaaacaatg ttactaaaag tatagttaca acaattggcc aataaggtat
    23281 tataagacta tataaactat caactatata cacttgaaaa tatctaactc caataaatgt
    23341 caatatagtc caatatacag aaaactttag acatactatt cctctactat tgtacttata
    23401 atctgaataa tcccaataga ccttattaaa atatactttc ataagtattc ctgtaatata
    23461 ttctactact gtcggcacta ctagacataa taaaagcaat gcaaatatat tattggggtc
    23521 aataaatctt gagacctcta ttataatcga cattgcaatt gcatacattg gtttaaatgg
    23581 accatttaaa aatccatctt cttgaaaatg cccttgttta taataactat ataagttttc
    23641 aattatccaa cctataaaac catacaagaa aaaattaaat aaaaaatata atagagaacc
    23701 tacattatcc atgaatattc ctcctagctg tttatactta ttttttctca tattcatgga
    23761 tttattctaa atcaaagaaa ttatatttaa tttatttaat taatacttta tattatagat
    23821 tgtgacattc tttagagttc aaacttttta ggtattctct aacttccagt aaattttcaa
    23881 gtatcttatg tgattgtgat ttaatttgct catctggctc ttttaaatct ggtacattta
    23941 tacatcttat accaccattg tatgcagctt cgactcccat aggcgaatcc tctatgacaa
    24001 tacaattttg gggattaaca tttatctttt tagctgcttt taggaatatc tcagggtttg
    24061 gtttagagtt tacaacatca tctccacaaa ctatagcatc aaagtaatct tttaaatttg
    24121 ccttagctaa tctctttact gctctttctc tctttgttga tgttgcaaca gccattttgt
    24181 atccattttc ttttaaaaaa gagattagtt cattgactcc taatttgata ggagctccct
    24241 tcctctccat aaattcaatc atgtttttag ttttttcgtc atataaatct attattggta
    24301 cagaactatc gtatatatct gtaagacctt ctattattcc tttacgattt cttcccataa
    24361 ctgatgtata aatttcctta gtcatagtat atccatactt ttcaaacgtc tccatccaaa
    24421 attcaagaga aattctctct gagtcaaaca aaactccatc catgtcaaaa ataattcctt
    24481 ctactttttg catacaattc ctccaatatt ttttgatata attatattac actttttatg
    24541 attaatttta caaccctcaa tttatccaat tctaatattg taaaattgta attttcaaaa
    24601 gttacacttt ggtttacttt aatatttgaa ccaagcatat aggatatcca cccacctata
    24661 ctgtcaaatc catcatgctc tatatcaagt ccaaaatact tattaatata gttgatagat
    24721 tcagttccat caactaagta agaacctgct cctattttct taatatgagt ctcttcttta
    24781 tcaaattcat cttgaatttc tccaactatc tcttctagta tatcttctat tgttaccaca
    24841 ccagatgtac caccatattc atccacaact atagcaagtt gaagtttttc ctttcttatt
    24901 ctctcaagag ctttatctat agttaaattt tcagatatat atataatatc tctcaatatt
    24961 tcttctagtt caattttatt ttcatttatc ttttgattgt ataaatctct tatatgtaca
    25021 aaacctaata tatcatcttt attttttctg catactggat atcttgtaac accttcctct
    25081 tttaaaatag ctaatatctt ttcttcagaa tcactttcat atatacatac catatcagtt
    25141 ctaggaacca ttatctctct aattttcttt tcttcaaatt caaaaatatt atcaactaat
    25201 ctttgctctg attcatctat aagtccactt ttataacttt cttctactaa tagtcttatt
    25261 tcgtcacctg tatggggttc atcaacctca tcagcttgtg aatatccaaa tggtttaaga
    25321 aataaatcag tacttaagtt gaaaaaatat attattggat atgttaactt ataaaatcct
    25381 actaataaaa aagatgtact caacattatt ttttctgtat tataaagtgc taaagcttta
    25441 ggaaccaact ctcctattac aacctccatc attgttataa ttaaaaaaga aatggaaatt
    25501 gatatagtat atataatact ttcactaaga ttaaatacac ttactattgg taaaattaac
    25561 tctttaactg tagattctcc catccaacct aatgcaagtg aacaaagtgt tataccaagt
    25621 tgacatgcag aaagatagga atttaagttg tcttttatta ttttacatct ttttgcatta
    25681 ttattacctt cagttatcat ggtatcaatc ctagaactac gaagttttac catagcaaat
    25741 tcacaagcta caaaaaaagc atttatcaaa acaagcatta ctataagtgt tacttttaat
    25801 aactcccgca taaagtattg gttcttataa tgtaagaaat ctataagaac tcaaagttcc
    25861 ccccttatat ttataaattt aatttataat atatattcta tca
//
LOCUS       DAEQAF010000051        25602 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.053, whole genome shotgun sequence.
ACCESSION   DAEQAF010000051 DAEQAF010000000
VERSION     DAEQAF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25602
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.053"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..2267)
                     /gene="slpA"
                     /locus_tag="KRN00_002232"
     CDS             complement(<1..2267)
                     /gene="slpA"
                     /locus_tag="KRN00_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBH1828097.1"
                     /translation="MNKKNIAIAMSGLTVLASAAPVFADDTKVETGDQGYTVVQSKYK
                     KAVEQLQKGILDGSITEIKVFFEGTLASTIKVGSELNAADASKLLFTQVDNKLDNLGD
                     GDYVDFLITSPGQGDKITTSKLVALKDLTGASADAIIAGTSSADGVVTNTGAASGSTE
                     TNSAGTKLAMSAIFDTAYTDSSETAVKITIKAAMNDTKFGKAGETTYSTGLTFEDGST
                     EKIVKLGDSDIIDITKALKLTVVPGSEATVKFAEKTPSGSVQPVITKLRIINAKEETI
                     DIDASSSKTAQDLAKKYVFNKTDLNTLYKVLNGDEADTNGLIEEVSGKYQVVLYPEGK
                     RVTTKSAAKASIADENSPVKLTLKSDKKKDLKDYVDDLRTYNNGYSNAIEVAGEDRIE
                     TAIALSQKYYNSDDENAIFRDSVDNVVLVGGNAIVDGLVASPLASEKKAPLLLTSKDK
                     LDSSVKAEIKRVMNIKSTTGINTSKKVYLAGGVNSISKEVENELKDMGLKVTRLAGDD
                     RYETSLKIADEVGLDNDKAFVVGGTGLADAMSIAPVASQLRNANGKMDLADGDATPIV
                     VVDGKAKTINDDVKDFLDDSQVDIIGGENSVSKDVENAIDDATGKSPDRYSGDDRQAT
                     NAKVIKESSYYQDNLNNDKKVVNFFVAKDGSTKEDQLVDALAAAPVAANFGVTLNSDG
                     KPVDKDGKVLTGSDNDKNKLVSPAPIVLATDSLSSDQSVSISKVLDKDNGENLVQVGK
                     GIATSVINKLKDLLS"
     gene            complement(2480..4069)
                     /locus_tag="KRN00_002233"
     CDS             complement(2480..4069)
                     /locus_tag="KRN00_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp12"
                     /protein_id="HBH1828098.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETAAK
                     IAQKQTYENVVLVNTDNTLADGLSASGLAGTVKAPILLSQRNSIPSDTEKMLKDVKKV
                     YIIGTEDSIGKSVENELKQKGIEVKRIGGNDRIETSYLIAKEIASIKPIDKVFITNGY
                     TGEADAMSASSVASRDGAPIILTNGKNVPFEKKEGVQCYALGSEEIISNDLVKKTNAV
                     RLAGEDRFETNKKVIKHFYSSAKEFYLSKGYQLVDAVAGSSIAKNAPIVLVDGNSDKS
                     VLRSADKITALGGIDEKTLEQCLSASSLDASAPTITVGNLNIYQGDKFDISKLNIVAK
                     DSNGNDLTPELIGNINTDKVGKYKVTIKATDIGGKTTSISVEVNVLEYKTNDMNSSEF
                     KRMVSSEMYSLVNSYRKEKGKEPLQVSKNLEGLSNSWSKYMADKGQFSHVIDGKKSVE
                     VFTGYGLRSEENIAFVPLVTKSTYTTKDAREVANVIFTVWKKSDKYNENMLNSDFVYT
                     GFGLYILPNGEVYATQEFLNK"
     gene            complement(4288..5889)
                     /locus_tag="KRN00_002234"
     CDS             complement(4288..5889)
                     /locus_tag="KRN00_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBH1828099.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTERSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNPLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSNKTV
                     LEGAKNITSVGEINEKVIQQCINSSKSNGQPPTITVGSTEIYKGERFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSRLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGSL"
     gene            complement(6256..8136)
                     /locus_tag="KRN00_002235"
     CDS             complement(6256..8136)
                     /locus_tag="KRN00_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBH1828100.1"
                     /translation="MSKRKSFIRTIAVSTMAVAITGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTNHKPALK
                     IVTYNNKTVDYENISSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYYIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGSGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGTDRFETA
                     IKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNDKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRIGGDTRYQTSINIAKEIDKTNNV
                     NKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            complement(8346..14309)
                     /locus_tag="KRN00_002236"
     CDS             complement(8346..14309)
                     /locus_tag="KRN00_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBH1828101.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNNESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENVSYYNIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKREFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDEISEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENINQTDNNSNNKDENNDKQQ
                     ENSDKQEVNSNTNQDKNNDKENSSMDKPNSDEDTPKEEGNISKDDNSTTSTYSKSALE
                     TYADVQNSDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNVYKEIPKPEM
                     NIPKINKISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTI
                     EVRDIEAYGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEF
                     QVVPDTKPEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIR
                     GTSSKIEGLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKEN
                     GGFGIPTNHIVDVVYPDGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRG
                     PIITFDKSYTMDTFMATPRFDVSDKTINDFEVRYWDENGQLHNLGDVPFETKTDPVNN
                     NKYVMVRLKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFIDDLQVEL
                     KEDVTQEKITELKDRLNTPDKASGEYHPYKTVIERELKLAQDLYNDRATLTDVTTVNQ
                     EINKLGKYKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYT
                     QYYGESGAYKSGEINLNTGKNVIQLSKLHSLDIECGGSLYIRYAEDTPSGGDIKVRVA
                     GATKIPHLNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSY
                     GYSEKTGVLNTTDIESDKVTLNVPATAVYQGISKGNADLNTQVDRLYNSMLAWEQIMD
                     LVYSERGVFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHV
                     GVEYGSVPGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLA
                     LLAQTFDDKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGS
                     MLKNNSDADLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFK
                     AWGVEITPELNSIMDSKNYEKESRKIQYVNDEARRKILNENIASMAKDTKVSASFSDG
                     IQSGSLVKSNKISIDLDVDKDKDKILGYEIIRSDGNYLDGENGTQVKYRTVGFVDAKG
                     NSKTKFTDNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITN
                     TVSDGDVRTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEE
                     NPYIIVDMKETLPIVGLKYTKPETEARKFSLKGLFNFRKNTSTTYNPLTNYKIQVSND
                     KKNWEDVSQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIE
                     VAELDIIGPPGDNIEIGTMNNADQTRTNGIGKLAEDYVYQSDDSSTSEDETGKIPAGS
                     IVITGEYSGNPAFNLPLLIDKNNKTISGEALLFAEVPEKGELGEISKGTWVYYMPKEN
                     FDSLSDKVKAELYRYNDLQGDTPVGQRFVSDTMYVPVGAKNYDELKTISLTDSNSKAR
                     KATRNSIDISNKKVITVSNKVKGNIVRDK"
     regulatory      complement(14433..14518)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(14690..16093)
                     /locus_tag="KRN00_002237"
     CDS             complement(14690..16093)
                     /locus_tag="KRN00_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBH1828102.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKIVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     gene            complement(16555..18450)
                     /locus_tag="KRN00_002238"
     CDS             complement(16555..18450)
                     /locus_tag="KRN00_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBH1828103.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKRYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            complement(19077..19220)
                     /gene="scfA"
                     /locus_tag="KRN00_002239"
     CDS             complement(19077..19220)
                     /gene="scfA"
                     /locus_tag="KRN00_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBH1828104.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            complement(19286..19648)
                     /locus_tag="KRN00_002240"
     CDS             complement(19286..19648)
                     /locus_tag="KRN00_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBH1828105.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGLLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            complement(19706..19999)
                     /gene="yajC"
                     /locus_tag="KRN00_002241"
     CDS             complement(19706..19999)
                     /gene="yajC"
                     /locus_tag="KRN00_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBH1828106.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            complement(20133..21254)
                     /gene="tgt"
                     /locus_tag="KRN00_002242"
     CDS             complement(20133..21254)
                     /gene="tgt"
                     /locus_tag="KRN00_002242"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBH1828107.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            complement(21333..21818)
                     /locus_tag="KRN00_002243"
     CDS             complement(21333..21818)
                     /locus_tag="KRN00_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828108.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            complement(21830..22855)
                     /gene="queA"
                     /locus_tag="KRN00_002244"
     CDS             complement(21830..22855)
                     /gene="queA"
                     /locus_tag="KRN00_002244"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBH1828109.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            complement(23173..24192)
                     /gene="ruvB"
                     /locus_tag="KRN00_002245"
     CDS             complement(23173..24192)
                     /gene="ruvB"
                     /locus_tag="KRN00_002245"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBH1828110.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            complement(24298..24900)
                     /gene="ruvA"
                     /locus_tag="KRN00_002246"
     CDS             complement(24298..24900)
                     /gene="ruvA"
                     /locus_tag="KRN00_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBH1828111.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            complement(24893..25402)
                     /gene="ruvC"
                     /locus_tag="KRN00_002247"
     CDS             complement(24893..25402)
                     /gene="ruvC"
                     /locus_tag="KRN00_002247"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBH1828112.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
BASE COUNT         7415 a         4794 c         2837 g        10556 t
ORIGIN      
        1 atacttaata aatcttttaa tttatttata actgaagtag ctataccttt accgacttga
       61 actaagtttt ctccattatc tttatcaaga actttactta tagatacact ttgatctgaa
      121 gataaagaat cagtagctaa tactataggt gctggagata ctaatttatt tttatcatta
      181 tcagaaccag ttaatacttt accatcttta tctactggct taccatcaga attaagagtt
      241 acaccaaagt ttgctgcaac tggagctgct gctaaagcat caactaattg atcttcttta
      301 gtagaaccat ctttagctac aaagaaatta actacttttt tatcattatt taagttatct
      361 tgataataag aagattcttt tataactttt gcattagttg cttgtctatc atctccacta
      421 tatctatctg gagatttacc tgtagcatca tctattgcat tttcaacatc tttagataca
      481 ctgttttctc cacctattat atcaacttgt gaatcatcta agaaatcttt tacatcatca
      541 tttatagttt tagcttttcc atctacaact actattggtg tagcatcacc atcagctaaa
      601 tccattttac cattagcatt tcttaattga gatgcaactg gagctatact catggcatct
      661 gctaatcctg ttcctccaac tacaaatgct ttatcattat caagacctac ttcatcagct
      721 atttttagag aagtttcata tctatcatct cctgctaatc ttgtaacttt aagtcccata
      781 tcttttaatt cattttctac ttctttagat atagaattaa ctccaccagc taaataaact
      841 ttctttgaag tatttatacc tgttgtactc tttatattca taactctctt tatttcagct
      901 tttacgcttg aatctaattt atcttttgaa gttaataata aaggagcttt cttttcagaa
      961 gctaaaggag aagctacaag tccatcaact attgcatttc ctccaaccaa tactacatta
     1021 tcaactgaat ctctaaatat agcattttca tcatcagagt tataatattt ttgacttaat
     1081 gctattgcag tttctattct atcttctcct gctacttcta tagcatttga atatccatta
     1141 ttatatgttc ttaaatcatc cacataatct tttaagtctt tcttcttatc tgacttaaga
     1201 gttaatttaa ctggtgaatt ttcatcagca attgaagcct ttgcagcact cttagttgta
     1261 actctttttc cttctggata aagaactact tgatattttc cactaacttc ttctattaat
     1321 ccattagtat ctgcttcatc tccatttaat actttataaa gagtatttaa atcagtttta
     1381 ttaaatacat attttttagc taaatcttgt gctgttttac tagaactagc gtcaatatct
     1441 attgtttctt ctttagcatt tattattcta agctttgtta ttactggttg aacactgcca
     1501 cttggtgttt tttcagcaaa cttaacagtt gcttcacttc caggaacaac agtaagttta
     1561 agagctttag ttatatctat aatatcactg tcccctaatt taacaatttt ttctgtagac
     1621 ccatcttcaa atgtaagccc agttgaataa gttgtctcac ctgctttacc aaatttagta
     1681 tcattcatag ctgcttttat agtaatctta accgcagttt cagatgaatc tgtatatgct
     1741 gtgtcaaaaa tagctgacat tgcaagtttt gttcctgctg aatttgtctc agtagaacca
     1801 ctagcagctc cagtatttgt aacaacacca tctgctgaag atgttccagc aattatagca
     1861 tctgctgaag cacctgttaa atctttcaat gcaacaagtt tacttgtagt tattttatcc
     1921 ccttgacctg gagaagttat taagaaatct acataatctc catcacctaa attatctagt
     1981 ttattatcta cttgtgtaaa caataattta cttgcatctg ctgcattaag ctcagaacct
     2041 acttttatag tagatgctaa agttccctca aagaaaactt taatttctgt tatacttcca
     2101 tctaatattc ctttttgtaa ttgttcaaca gctttcttat acttgctttg taccactgta
     2161 tatccttgat caccagtttc aacttttgta tcatctgcaa atacaggtgc agccgaagct
     2221 aaaactgtta aacctgacat agctattgct atatttttct tattcattcc ttaaattcct
     2281 cccaacatta tattaaaatt acatctcttt attatgtaca tagaataatc atccatatat
     2341 tcctaatatt tctcacatct ctataataat ccattttaat tctttttgca agtcattttt
     2401 ttgaaattat tatttttccc aagcatatga gtttttatac ccttaaattt caatatttaa
     2461 taacttaaaa aatttaattt tacttattta aaaattcttg agtagcatac acttctccat
     2521 taggcaatat atacaaacca aacccagtat atacaaaatc actgtttagc atattttcat
     2581 tatatttatc cgattttttc caaactgtaa atattacatt tgctacttct ctagcatcct
     2641 ttgtcgtata agtgctcttt gtaacaagtg gtacaaaagc tatattttct tcacttctca
     2701 acccatatcc agtaaatact tcaacagatt tcttaccatc tattacatgt gaaaactgac
     2761 ctttatctgc catgtactta gaccaggaat tagaaagccc ttctaagttt ttagaaactt
     2821 gtaatggttc tttccctttt tcttttctat atgaatttac caaactatac atttcactag
     2881 aaaccattct tttaaactca ctactattca tatcattagt cttatattca agtacattta
     2941 cttctacact tattgaggta gtctttccac caatatcagt agcttttata gtaactttgt
     3001 atttaccaac cttatcagta ttaatatttc ctataagctc tggtgtcaaa tcattaccat
     3061 tgctatcctt tgctacgata ttcagtttac ttatatcaaa cttatcacct tgataaatat
     3121 ttaaatttcc aacagttatt gttggtgcac ttgcatccag tgatgatgca cttaaacatt
     3181 gttctagtgt tttttcatct attcctccta gtgctgtaat cttatcagca cttctaagta
     3241 cagacttatc actatttcca tcaaccaata caataggtgc atttttagct atagaagaac
     3301 cagcaactgc atctactaat tgataacctt tagaaagata aaattctttt gccgaactat
     3361 aaaaatgttt tataactttt ttattagtct caaatctatc ttctccagct aatctaactg
     3421 cattagtttt tttaactaaa tcattactta ttatctcctc tgaaccaaga gcataacatt
     3481 gcacgccttc ttttttctca aatggaacat ttttaccatt agttaaaatt ataggtgctc
     3541 catctcttga tgctactgat gacgcactca tagcatctgc ttcacctgta taaccattag
     3601 ttataaaaac cttatctata ggttttattg aagctatttc ttttgctata agataacttg
     3661 tttcaattct atcattacca cctattcttt taacttcgat tcctttttgc tttaattcat
     3721 tttcaactga ttttcctatt gaatcttcag ttcctattat ataaaccttc tttacatctt
     3781 ttaacatttt ttctgtgtct gatggtatac tgtttctttg tgataataat ataggtgctt
     3841 taactgttcc tgctaatcca cttgcactta atccatcagc tagtgtatta tctgtattta
     3901 ctaatactac attttcatat gtttgtttct gtgcaatttt ggcagctgtc tcatatctat
     3961 ctttcccttg tatcttttct atacttgaaa gtgcattgat atttggtgct cctgccatta
     4021 ttaatgatat tgtcaatcct attgataata ctctcttatt taccttcatc aaactcctcc
     4081 tactaatttt tttatataat tcagctaatc ataaattaca tcctcagtag tgattccctc
     4141 aaaatctata aactactaaa acaaaaaaca cctaaaatac cataacctgt aaatcaataa
     4201 caaaacagat tacaaaaagt actttagatg tgattttcat tttataatat cagtaaatta
     4261 acaaaaaaac aagatttatg gaatttttta caagctacct tcattgccat ttaaaaactc
     4321 ctgagtagca tgcacttgac catcagataa tatataaagc ccaaatccag tactataaaa
     4381 ctcatcacta agcatgtttg cattgtactc tggggatttc ttccacacct caaatatagc
     4441 ctttgccaag tcttttgcat cttgtgtcgt ttgaacgttc ttagaatcta tataaatata
     4501 tgctatattt tcctcacttc tcattccaaa ttcagaaaat acttgtggag cattttttcc
     4561 atctatataa tgtgcaaata cttttttatc catcatatac ttagaccatg catttgccat
     4621 accttctagc ctactagata ctaccaaagg ttctttgcct ttttcttttc tataggaatt
     4681 gattaagtta tacatttcag tagataccat ttttttaaat tctgggctgt tgtaatcatg
     4741 agatttgtca tccaacactt ttatttctac tctttttcct gtgctttttc cccattcgtc
     4801 tgtagctttt aatgtcaata tgtatgtacc tactctattt gtatctataa acccatcaac
     4861 ttctattggt aataccttcc ctgtgttatc tttagctact atatttaact tgccagtgtc
     4921 aaacctttca cccttatata tctctgtact tccaactgta attgttgggg gttgtccatt
     4981 tgactttgac gaatttatac actgttgtat taccttctca tttatttcac ctacagaggt
     5041 tatattctta gctccttcta atacagtttt attgcttcca tcatttacta gtaccattgg
     5101 agagttttta gtaagtggtg cagctgctat tgcatctact aattggtatc catctgatac
     5161 atagaatcca tctgcactat taaaaaagta gtctattacg tttttgttag tttcaaatcg
     5221 gtcagttcct tctattctta ctgagtttgt atttttaact agaggattac tcattatctc
     5281 ctctgaacct atacaatatg attgaatatt ttttacatca aaaggcacac tctttccatc
     5341 tgtaagtatg attggagctc catctctagt agctactgat gatacactca ttgcatctgc
     5401 ttctccacta tatgcattag ttaatagtac tttatccact ttttttatag ttgctatttc
     5461 tttagctatt aaatagcttg tttttagtct atcttctcca ccaattcttt tgacttctat
     5521 atttttagaa tctagttctt tttctactga tttacttata gtatcttctg tacctattat
     5581 atatgctttt ttgatatttt ttagacatct atttgtgtct gctggtatct tattttgttg
     5641 tgtaaatagt attggagctt ttgtagctcc cgataatcca cttgcactta atccatctgc
     5701 aagtgatctt tctgtattta ctaaaattac tgtttcataa gtctgtttat cagctatctt
     5761 tgctgctgtt tcatatctat ctttaccgta tattttttct actactgatg atgcatttac
     5821 acttttgaag tttactaaga ttaatgatac tgctagacct aatgataata tttttttgtt
     5881 cattttcata tccccctgat gatttttata ttttatattt atattgtgat tattttccat
     5941 ttattttctc tttattttcc atatattata gagtatatat gatatgaata tatctcgtct
     6001 atatattagt gttttatttt attaaattta aaaaattatt tttaacttct ttttaaacat
     6061 attcaaaatt gaatttgtat ttatatatat aaaagatatc tgctttattt aaaattaaac
     6121 ttaatatagc tcaaattatt atacatttta acctcaatat tattaaattg ttaagataat
     6181 gaaaataaaa taagaatgca tttaaatata taactttata tctaaataca ttcttatttt
     6241 ctatttactt aatatttatt tttcaattaa actcttaatc ttatctatta cagatgaggc
     6301 tattcctcca cctacttcaa acaactttga tgaattttta ccttttaatg acgattcttg
     6361 tgatttatct aacgtatttg tagcaagtat aactggtgaa ttgtttttag ctgctaatgg
     6421 tccaactgct aaagcgtcta taagtttatc ttgatttgca actacaactc catctagttt
     6481 agattgagag tagaatttat ctattacttt ggcattcgtc tcttgtctag tttgacctgc
     6541 cactctattg tttgatatat ctttgtttgc tatttttcca acttgttcaa tagccttgtt
     6601 agatattttt tctactccac caataaaata tatatttgac accttatttg atttaataaa
     6661 ttgttcagct tcattatcta caccatcttt ttgtgtaagt actattggag ttttttcttt
     6721 gccagccagt gatgctattg ataatgaatc agcttctcca tttcctgctc ctatatacaa
     6781 cttgtttaca ttgttcgtct tatctatttc ttttgctata ttaatagaag tttgatatct
     6841 tgtatctcca cctattcttt gtactgatat ttttgaattt acagctttga tagcttcaac
     6901 aactgaattt ggcattgagt tgtttccacc tatcacaatt acttttgatg gatttagcct
     6961 tttcaattct tctacagttt tttgaggaag tttatcattt gatgataaaa gaatcggtga
     7021 gttttttaca ctagcaagtg gtgtagctgt aagcccatcc accatacttt tatcttctcc
     7081 atttactatt acaactgtat ctgattttgt ccaaccactt tgagatattt tgatagctgt
     7141 ctcaaatcta tcagtacctt ttaatttttt gactgtgaca ttagatgtag aatcacttga
     7201 atttcctcct ccagagcttc caccactaga tgagccgcct gaattacttc ctccaccatt
     7261 atttccacca ctaccattat ctggtggtaa ttcatccggt tttgataatt cattttcaac
     7321 tatgtattct aaactttttg gaagtgtaac ttcaacatat ttgtttattg tagcttttct
     7381 tcccttagtt gttttttgtg ctaatccaag ttttaatatt acatttgaac cactttcttg
     7441 tgtttcttta ctaacaatat aatagtttat cctaatattg tttaataaat attcaagtgc
     7501 ttcacttttc tctaccttat acttttcagg gtcattttta ctagaaccag ttccaccaat
     7561 tggttttact tcactctcat taataagggt aaatattaat ccttcatcag agcttatatt
     7621 ttcataatcc actgttttgt tgttatatgt tacaattttt aaagctggtt tatggtttgt
     7681 tccttttcct aaaactttat agtcagcatt tgagttactg ccagattttt ttacagatat
     7741 tcttcctata ttcaatctat ttccgtctag taagtcttca tttgatgtaa cgtatatatc
     7801 taatgtagtt gtattacttg atttgttgta ttctgctcta caagtagcat ttgcatttcc
     7861 actttttatc tgagatttta tattatcaga ccaagtaatc ttttctttct gctcattatc
     7921 tactacttca acctcacctt gtacttttat actggcttga aatgaatata ctatgttttc
     7981 tactgagtcc acagatatat ctatagtatt tactttctca tacgtttttg ttccttgtaa
     8041 aactggagct gcatatgcac atgtagcact accagttata gctactgcca tagttgatac
     8101 tgctatagtt cttataaaag attttctttt actcattaac acccgtcctt atctatcatt
     8161 aactaagtgg ataaatttac ttatccacct aacttttata tttaatttat aaattaccct
     8221 aaatttatgg ttacatttat atactttact tttaatatct actattttaa aactattcta
     8281 gtacctaatc ttattagata tacaatgtta gtgttagtat ttttacgttt ttagagttcc
     8341 acctactatt tatctctaac aatattaccc tttactttat tgcttacagt tataaccttc
     8401 ttattactga tatcaataga atttcttgta gcttttctag ctttactatt actatcagta
     8461 agacttattg tctttaactc atcataattc ttagctccta caggtacata cattgtatca
     8521 cttacaaatc tttgacctac tggagtatct ccttgaaggt cattgtatct atatagttca
     8581 gccttaacct tatcacttaa agaatcaaag ttttcttttg gcatatagta aacccatgta
     8641 cctttactga tttcacctag ttcacctttt tctggaactt ctgcaaataa aagtgcttct
     8701 ccagatatag tcttattgtt tttatctata agtagtggta aattaaatgc tggatttcca
     8761 ctgtattcac ctgtaataac tattgaacct gctggaatct tacctgtttc atcttcactt
     8821 gtgctagagt catcactttg atatacataa tcttctgcta attttccaat tccattagta
     8881 cgagtttggt ctgcattatt cattgtgcca atttctatat tatcacctgg aggtcctatt
     8941 atatctaatt ctgcaacttc tatattagac ttattatttg agattagttt tacatatcta
     9001 gcttggtatg tccaaagttt accatcttta ttaaatgtaa ctctagcttc attatcttgg
     9061 tcttttcctc caccaactaa atcttgtcca tattcaaaag ttccttgact tacatcttcc
     9121 cagttctttt tatcattact tacttgtatc ttgtaattag ttaaaggatt gtatgttgtg
     9181 ctagtattct ttctaaagtt aaataatcct tttaatgaga actttctagc ttctgtctct
     9241 ggttttgtat attttagtcc tactataggt aatgtttctt tcatgtctac tattatatat
     9301 ggattttctt ctacatttat atcagggtct ttttgagggt ctttgttcca ctctgcttta
     9361 cttattatct ttcctttata tgtagtactt gcatcattat cttttatatt atcaatttca
     9421 ggattttgta atggtccatg tgagtcattt tcagttctaa catcaccgtc agaaacagta
     9481 tttgttatga atgaccatgc tgatttattt attttccctt catctgataa ttttacagta
     9541 ccaacttcaa attcttctgt tggatttagg tgataatcat atgcaactac cttatatgta
     9601 aatgctctgt tattaagagg agatatatta tcagtaaatt tagtcttact atttcctttt
     9661 gcatccacaa atccaactgt tctgtatttt acctgtgttc cattttcacc atctaaataa
     9721 tttccatcac ttcttattat ttcgtatcct agtatcttat ctttatcctt atctacatct
     9781 aggtctatag atattttatt agatttaact agagaaccac tttgtattcc atcagaaaaa
     9841 ctagcactta ctttagtatc ttttgccata ctagctatat tttcatttaa aatctttctt
     9901 ctagcttcgt catttacata ttgtatcttt cttgattctt tttcgtagtt cttactatcc
     9961 attatactgt ttaattctgg tgtaatttct actccccatg ccttaaagta atctcttaaa
    10021 tctttttcaa caacacttga tgccattgct actagcattt ggtcttttgg taaactatta
    10081 attgggtcac tacttgaaag tgctctgtat tttcttgaaa tctttgcata gaatgtatca
    10141 ttacttaaat cagcatctga gttattcttt aacattgaac ccgtaaaatc atcatcataa
    10201 gctaaatgta attgccataa cattccaagc ctttcaaata cattgcttgg tatacctaag
    10261 ctatttgaag ttacatgctc atatatctta tccattgttg aaccttcaag tcttgaatgt
    10321 gtcttatcat caaaggtctg agcaagtaaa gcaagtacat tgttactagt ttcgctatat
    10381 gtcatctttc caatatctgt aacatgtcct atctcatgac ctattcccca tccaaataag
    10441 tttcctcctg tagcttttcc actatcatct atttggaaag gtactccatt cataagccct
    10501 ggaactgaac catattctac tcctacatgt aatccagaag catacataaa tgctccaata
    10561 aacattcttt ggtattttat gttcatacga gattttggag ccatatcatt tttagttaag
    10621 ttaaattcat tatcatctac agttccatta ccatctaagt cttgtgtttt aaatacacct
    10681 ctttctgagt aaactaaatc cattatttgt tcccatgcaa gcatactatt atataatcta
    10741 tctacttgtg tatttaaatc agcatttcct tttgatatcc cttgatatac agctgttgca
    10801 ggaacattta atgttacttt atcactttca atatctgtag tgtttaacac accagttttt
    10861 tctgaatatc catatgaatt accaacattt gttcctggat aatatggttc tccttttaca
    10921 gcatctttat atttagctaa ttcttctata tatgctttta tctttttctt agattcagaa
    10981 actcccgcag gactcttatc atttattgtt ccatttagat taagatgtgg tatcttagta
    11041 gctcctgcta cacgtacttt tatatctcct ccacttggag tatcttcagc gtatcttatg
    11101 tataaacttc ctccacattc tatatctaaa ctatgaagtt tgcttaattg aattacattt
    11161 tttccagtgt taagatttat ttctccactc ttatacgcac cagattctcc atagtactgt
    11221 gtatatatca acttaggagt ttttccactt ttacttccaa catatactgt gatttcatct
    11281 cctgctctag cagctactcc taatgcctgc cagtcatttt gcatacctaa attattggaa
    11341 tttacagtat actgtccatt tttatcttta tattttccta atttatttat ttcttgattt
    11401 acagtcgtta catcagtaag tgtggctcta tcattatata agtcttgagc taattttaat
    11461 tctctctcaa taactgtctt atatggatga tattctccac tagctttatc tggagtattt
    11521 aatctatctt ttaattcagt tattttttct tgagttacat cttcttttaa ttcaacttgt
    11581 aggtcatcta taaatagatt tcttacatca tcttctatac tgtcatactc ataaaactta
    11641 agttctgata tattagactt atatgaatag gatgagcaaa cacttacttg tatcttggta
    11701 gcagttattg gttcttttaa tctaaccatt acatacttat tattatttac agggtctgtc
    11761 tttgtttcaa aaggaacatc ccccagattg tgtaattgac cattttcatc ccaatatcgt
    11821 acctcaaagt catttattgt cttatcagaa acatcaaaac gaggtgtagc cataaaagta
    11881 tccatagtat aagatttatc aaaagttatt attggtcctc tattcgttcc ctcagctgca
    11941 ttatatgttg gaaatgtcca atgtgttgta aagtccccat ctactacatt gaatttatca
    12001 aatggatttt tatcactata ttcacttttg tcatatccat ctggataaac aacatctaca
    12061 atgtgatttg ttggtattcc aaatccacca ttctctttag gagtattaat taatctatag
    12121 ttaggtgttg ttggtgcatc catactttca gttgtaccta tataggtttt agacattcca
    12181 ctagttccca agtggttagt agctgtcatt ctaacttcat atgttgtatt atccttaaga
    12241 ccttctatct ttgaacttgt cccacgaata agcttatcat tgtattttat ccaagaccca
    12301 ttagaacctt tttctttata gtacaagtca aaatctttag cttgtttatg atttttccag
    12361 cttacatcaa gagatttaaa tttaccttta acgtttatac cttctggtgg ttctggcttt
    12421 gtatctggaa caacttgaaa ttctaatata ctatctgggc taaattgtat aggtttatag
    12481 tttgaatcta cattttctgg tactccatct aagttttctg gtgttgcatc tttataaccg
    12541 ctagaccaat ctccatttaa agattgtatg ctaactctat atagtccata tgcttctata
    12601 tctctaactt ctattgtatt tttactagtt tgtaattttt tagtagataa tacttttccc
    12661 ttactatcaa ttttatctag tataagttcg tatgctgata catttacttc attattccaa
    12721 taaaaagata ctttttcatt tccaacagca gtgctagtcg atattttatt tattttaggt
    12781 atattcatct ctggctttgg tatttcttta tatacattgt ttaaaaattc aacttttgat
    12841 atttctgcaa gatttctatc gtttgctgtt gtagctgtta tttttatagt tatctttttt
    12901 actgctactt gtttaccaag atttattact atatcactat tttgaacatc tgcatatgtt
    12961 tctaatgctg acttactata tgtagatgtt gtagagttat catctttact gatattaccc
    13021 tcttcttttg gagtatcttc atctgaatta ggtttatcca ttgatgaatt ttctttatca
    13081 ttatttttat cttgattggt attagagttt acttcttgtt tatcgctatt ttcctgttgt
    13141 ttatcattat tttcatcttt attatttgag ttattatcag tctggtttat attttcatct
    13201 ttattattta cttcttcttg atttacttct tcttgttcgt tatttacttc ctcttgttgc
    13261 tcctcatctt ttaagttttt catatattct ttgttttcat aaggaatctg ttgaacatta
    13321 ccatctttgt cagtaacctc aactattcct tttgctggag cagtaccttc tggagctttt
    13381 atattgatga cttccatatt aagtgcttct gataaagcta tatccattac tgctggtttt
    13441 tcctcagata tttcatcatt ttttgaagat attgtaactc cattattttc tccactaaat
    13501 aaattttcta cattaccatt aatatctaca tcactatttc cttttaattc aaccttactt
    13561 gtatctacta taggattggt agatactata ctttctaggc tttttgcatc ttcactttgt
    13621 cctaaatttt tctgtacata atctaagtca acaatatcta cctttccatc tctatttaaa
    13681 tcaaattctc ttttatttga atctatattc tctaaaacct tattataatc actcttatct
    13741 actttaccgt ctccatttac atcacccatt aagaataatt cataatttaa aggtttattt
    13801 ttattatcta cacttgctct attgcttaat aagactcttt gtgaataact tgatatatca
    13861 atgtctttaa tttctttgtt cttaaatcca gctccagaga cttctacatt gtattttcca
    13921 acaggtaaat tattaaatac aatattataa tatgatacat tctcatcttt attttttatt
    13981 tcacttctac ttgcagataa tttttttata gtatattcta tattatctgt cccaacattt
    14041 actgttcctg aatctttttc tccaagcttt attattccac tattgttact atcatctttt
    14101 aatcgtaact gcatattagt catactttct gactcgttat tttttattgg cagtgaaaaa
    14161 tttaaatcta cttcaagact cccccttaac ttttctgtaa ctgatttttc aactgccctt
    14221 agcttcccct ctaatatagg ttctgcaaaa acgtttagtg gtgcactaca catagatact
    14281 gctagtacac aagatattgc ctttttcatg aaataacaat cctcccttaa taaatatcta
    14341 atttttcatg aatttaaata ctataagttt cagacaataa aaaaagacac tcaaagagaa
    14401 tcttaattat aaaataaaaa gactttactc tttttagcaa ctggctgata tggctttaaa
    14461 agctttaatc cctatagttt tgcgtcatta gatttcccta attttgccat ttaattttca
    14521 ctactttctt acccatttta tactatattt aaacttttta atacaatttt tttagattaa
    14581 attataaaaa aataacattt atattaattt attaatataa atgttatttt ccattataat
    14641 ttaattattt atatagcttc cttacaagca taattttgtg tatattttct tattctttat
    14701 atcttccata aaattcatgt gtagcatata gattcttatc tcctgttata gctataccaa
    14761 atcccattat ttcataccct ttatgcaaca tattagttcc ttcttctgga tttgtcttcc
    14821 actcattaaa aataaagttt cctatatcat ctgcatctct atttgtatat acaggtttat
    14881 ctggaatttt atatttaatt atattttcac cttgaactgc tatatatcca ggtttaatct
    14941 cactccaatc taagtatttc aaaaaagtag aatatgaatt ttttccattt atcgtatgag
    15001 ataaagtctt cttatttgcc attaaattag accaatcatt tgctagaccc tctaatctgc
    15061 ttgctacaga taacgctctt actccattct cttttctata ctgctttgta agagcatata
    15121 ctttaccctt tattctctct ttaaatgctc tatcatttgg attgtaatat aaaccttgtt
    15181 gatttggtga agcttgattt atacattgct tgataacatt ctgatttata cctcctagta
    15241 cagtcaattt gtctgcacca cttaaaatac tcttgttact gccattttca actaaaacta
    15301 caggagcatt ttttgctatt gtagaggcag ccaaagcgtc tgttaattgt aagcctttac
    15361 ttagataaaa ttctttacta tttttataaa actcttgtat aactatctta ttagtttcaa
    15421 atctatctgt gccacccaat ctaatagaat ttgtgctctt aactaattcg tcgctgatta
    15481 tttcactaga accaagcgca taactcttta agcctgtcgt gtcaaatccc acactatttc
    15541 catctgtaag tattataggt actccatctc tagcagctac tggtgatgca cttatcgcat
    15601 ctgcttctcc tgtaaagcca ttggctataa ttactttatc tattggctta atttctttga
    15661 ttttttcagc tatttttata cttgtatcaa atctattttc accaaagatt ctttgtacaa
    15721 tcttcttttt ggatagtaac tgattctcaa catttttact tattgttgat tctgagccta
    15781 ttatatacac agtctttgct ttgtttaatc tttccatagt tgtgtttgga atctggtttt
    15841 gttttgtcat caaaataggc gcatttaagg ctccagctaa accacttgca cttagaccat
    15901 ctgctaagct attatctgag ttgattagta ttgctgtatt gtagttttgc ttatctgcta
    15961 tttttgctgc tgtctcatat ctgtcattcc cttttatttg ctcaactgat gtcaacgcat
    16021 ttaccatagg agtatttacc attactaaaa atagtgtaag tcctatagct aatatctttt
    16081 tactattctt catattattt tctaccccca atgtactttt catatttttt attagtactc
    16141 atacttattt ttaatcaaaa gttacaattt tgttaccata ttttatatat gataccatag
    16201 ttatccatac aactcaaaca atatacctaa agtttttatt ctctataaat tcaaaacatt
    16261 ataatttatt ttatttaatt aagttataag ttcaaaataa tttatgttaa caagatgttt
    16321 aatcattata agaagtatct ttttataata atttttgcaa tatgaatttc tcaacattat
    16381 aatcaaaaaa taaaataagg tatctcaatc taattctaaa tgagacacct tatttttatt
    16441 attttatctt gttatttgta tattttataa tatctacact atgtcttaca tattaacgca
    16501 ttgtataatc atatattatc taaataaact tttaatatta attcctatat cttattagtt
    16561 cttagtaaat aagtttattt tttctgctat tttttcaata gcgtttttag ctattccttc
    16621 acctatttgt actaacttag tagcattctt aagtcttaac tcaactactt cttcttgtga
    16681 tttagaaagt tcttctgtag ttaatactat tggagccttt gaactagctg caagtggtgc
    16741 tgctgtaagt gcatcaacta attgtccatt tccacctaca taaccatctt ttgctacata
    16801 tgctttagtt gcacctgcat agtatttatt gattacttta gcattagtat cttttctatt
    16861 ttctccagct aatctttcaa ctttattatt taaatctata tcaactaatt tgtcttcaac
    16921 ttcttttgat acagaatttt ctccacccac tatttctaat tcttttcctt ttaataattt
    16981 ttcagcattt gcatctaatt cgttacctgt aactattatt ggagcaccaa attgagcagc
    17041 tctagctgat atactcatag catcagcttc tccatttcca cctactacaa aagcagtctt
    17101 aaatgtatct tttaattgtt ttgctatttc taaagaagtt tcaaatctat cttctccaga
    17161 aactctctca actttactta cacctaattt agaaagtttt tcttcagttt cttttgatac
    17221 tttagattct ccacctacta tatatatttt cttagaagat agattacttc caagtactct
    17281 taatatttca gcttctattt ctgatggtag tgaatctttt ttagataata atattggtgc
    17341 atttttttga gaggcaagtg gtgctgatgc taatccatca actatagcat cttctccaac
    17401 taaaattata gcttctgctt ctccatcttt gaatctctct ttactaactt ctactgctgt
    17461 tgtaaatctt gaatcaccag ataaaacttc tacttttaat tcttttccat cttttacatc
    17521 agttaatact ttgtgtaagt ctctaactaa cttatggttt ttacttgaaa cacttattgt
    17581 ttctggcttt tcatttgcct tacttaaaac tatatcaaag cttgattttt ctggtttatc
    17641 tttatcatca ctatcttctt gttcttgagt aaggattgct tcattttcaa atgttaaagc
    17701 atatccattt ttaactttat taactatttc tcttcctaat gtagttaatc taattccatc
    17761 aaataattct tctgctgata tgtcttgtaa atctgcgttt ttaactgtta tcgtatgtaa
    17821 ttcttttgaa tctatgtcac tataacgctt ttcataacct tcaaaagtac cttcttctga
    17881 tgttatcact tttgagaaat ctaaatgttg gtctcctaca tttaatgtaa taacatttgc
    17941 tgaatctttt gctcttttta cttcaactgt atttgtagat tttatagttg ctgttaactt
    18001 gttgtcagaa tcttctgcta aagttgcatt gtaagcatta actgcatcta ctatttcttg
    18061 agcagttttg tagttttcaa ttttatagtc aactactttt ccacctaaca cttgatgtcc
    18121 tttatcttga atagtaactt ttaaactttg cccttctgtt aaagagttta tcttattttg
    18181 taattgagtt gcattagtta agtttacatt gtctactttt atatcgtaaa ctctatcatt
    18241 tacatttgct cctgcttttg tatcttcaaa cttaacttct aatgcttttc taacctcttc
    18301 gattagttta gcagaatctt tcgcacttac tgtgtaattt ttatcaacat tttctgtcac
    18361 agtattgtct gcgaatattg gtgctgctgc actcataact gtagcacctg ccattactat
    18421 tgccatactt ctctttttgt tgcttaacat atttatgtcc tccgaatatt attttttatt
    18481 ttttatattc gtatttccca cacataaata atattatata taatattatt tttcaatata
    18541 ttttatgtgt ttacataatt tactaacaca aacactaata atatcttctt gaaaccattc
    18601 cccctactta gctctctata attatgctca aagatagaaa tccctatttt atagtgattt
    18661 tctactaaac aatcatatac taacaaaagt attcaaactc catttttata tactactatg
    18721 cactaatttt tgctttactc ttattactta aatatatatc actaaattaa tatctatctc
    18781 catatattaa aatatataac atattataaa aatcatcata aattagagtt taaaattaaa
    18841 aattattcta atacatgtaa ttgataaaaa ataaaatata agagtagcta ctttaaaatg
    18901 aatgctctta tatgattaga tatttttgca taattaaacg ataagaaatc aaatttaatt
    18961 ttacataaat agaatatata tttttatata ataattgaaa ataaaagagg atacctcata
    19021 atgataaaag aatcactttg agataccctc ttacaaacaa ctaaatcaat aattttctat
    19081 ctttcacact cttgatttgc aactgtacaa gaagttttac aagctgattg acaagaagtt
    19141 tgacactctc cacatccacc ttttgcagca ctttgcttta aagtagcttg agataaagtt
    19201 tttacatgtt tattttccat tttcaacgcc tccatttcta attgtttcct attgattata
    19261 tcataaaact actttaatat aaactctatt taaagttgac acccaatacg cctccaatgc
    19321 ctcctgctgc tgatattaac aataacttat aaatcatccc tacttcaaat acaaactttt
    19381 cttgtgctaa aaacacagtc aaaaaaatac atactatgta caaaagtcct actaaaagcc
    19441 catacataag tcctttttct ttcatgtgtt ttgaagtgta aaaccctcct atagctgcag
    19501 aaatagtagt tataaatgat gagaccatag ttatattatc tccaccaata tctgtaaatg
    19561 tcaaaaataa gttatacact aataaaacag ccaaagttat tatatatgca tatcctagac
    19621 ctttaaaaat ataattagat tttcccataa aaaaacctcc tctcaaatta atatatattc
    19681 gagaaaaggc ttttaaatta ctaatttagt cttcttctat ttcttctttt ttagatttaa
    19741 cagttcctat agcccatttt tcaaatggaa ctttagttct atttggtcct aattctaata
    19801 ttacaacatc atcttcaact ttagctacat tagctactat tccacctatt gtaatgacct
    19861 tgtctcctac acttaggcta cttctcattt cttttaattg tttgtctttt ttcttttgag
    19921 gtctaatcat taggaaataa aagattgcga ttactactac ccatagacct atactcataa
    19981 ttatttgttg ctgtggcatt aatttttcac tcctttgtaa attatactct tttgtaaatc
    20041 ataataaatg tttatataac aatttacttt ctctatcttt gagtactatt gaatattata
    20101 tattaaaatg attataatta atagtgcaaa acctatattt catatccata ttttgcaaaa
    20161 aattcatttc taaaatcaag taatctatct tccattatcg cttgtcttat ttgtttcatt
    20221 aaatttaata aaaagtgaag attatgagta gttattaatc ttgcacccag tatttcattt
    20281 gcttttataa ggtgtcttat ataagctctt gaatagtttt tacaagcata acaatcacat
    20341 tcagggtcaa gtggagtaaa gtcttcagca taagttgcat ttctaactac tactttacct
    20401 tggctagtca ttgcagttcc atttctagcg atacgagtag gtaggacaca atcaaacatg
    20461 tctactcctc ttataacacc ttctactaag tcatctggac taccaactcc cattaggtat
    20521 cttggtttat cctttggcat aagtggagtt gtatgctcta gcacatcata cataagtggt
    20581 tttggttctc caacactaag tccaccaata gcatatcctg gtaaatcaat attagttatt
    20641 tctttcgctg attgttccct taagtcttta tacatcccac cttgtattat accaaataaa
    20701 gcttgcttgt cggtattatt atgggcatct ttacatcttt ttaaccatct tgttgttctt
    20761 tctaaagaat tttttacata ttctctatct gatgggtatg gtgcacactc atcaaatgcc
    20821 atcattatgt ctgaacccaa tgcattttgt atttccatag ctttttctgg agttagaaaa
    20881 tgttttgaac catctaagtg tgacctaaat tctacacctt cttcttttat ctttcttaaa
    20941 ggccctagac taaatacctg gaaccctcca ctatctgtaa gtattggttt atcccaattc
    21001 ataaacttat gaagaccacc agctcttttt ataagttcat gacctggtct catatataaa
    21061 tggtatgtgt tactaagtat tatttgtgaa ccaatctctt ttaattcttc tggtgtcata
    21121 gattttacag ttgcttgagt tccaactggc atgaatattg gtgtttcaat aatcccatgt
    21181 ggagtgtgta atcttcctaa ccttgcacca ctctgcttac aagtctttat caattcgtat
    21241 cttactgcgt acataaagtt ctccttaatc atatttattt ctcattattt cttaagatat
    21301 atttgtaata agctattcat ataatttatt gtctaaatag atttatcttc gtcttctttg
    21361 ttctgttgtt ccttaattgc ttcttcatca tgaatactca ttatattaag agcactcttg
    21421 tcttttgtta ctaaaaactt ttttatagca aatagtcctg ctatagctat aactcctatt
    21481 aaaacatcta tcataccttc atttttaggc agtagcaaca tttttctagc tattgcgtaa
    21541 agtaatgcct caataaatgc tcctggtata tgaagagata gcattactac aagttcaaca
    21601 cctattacta aaagtaatat ttgtgctaaa aaatcattaa gctgactgta ttgtactgga
    21661 ttttgaaaat caactatata tgctccccac ataagtctta gaacatctat agttcctaaa
    21721 aatactgcta ttagaactac tactgctaaa acacgttcaa atataaaagc aatctttaat
    21781 atagggttat tctttttttg tttttgtaaa ctatgcatcc attacctccc tactttataa
    21841 tcatagcatc tccaaaactg aagaatctat atctttcttt tactgcctca ttatatgcat
    21901 ttaaaacatt atcctttcca caaatagcac ttactaacat tattagtgta gactctggta
    21961 agtgaaaatt agtaataagt ttatctaaaa ctttaaattt ataacctgga tatataaata
    22021 tttctgtcca tccactagtt tctttcatct ttccatcctc attacaagct gattctatag
    22081 ttctacaact ggtagtacca acacatatta cattttttcc attttccttt gctctattta
    22141 ttttgtcagc tgcttcttgg ctaaccatat aatattctga atgcatcttg tgatttaaaa
    22201 catcctctac ttttactggt ctaaaagttc ctaaaccaac atgtagagtt acaaaggcta
    22261 tatctacacc tttttctttt attttattta acaattcttc tgtaaaatgt aatcctgctg
    22321 taggtgctgc tgctgaacca ttatgctttg aataaacagt ctggtatctt tctttttcat
    22381 ctagtctagc agtgatatat ggaggtagtg gcatatttcc aagttcatcc aatatttctt
    22441 caaaaattcc atcataatgg aattttataa ttcttgaacc ttcatctgat aaatctacaa
    22501 cttctccaat tagctttcca tttccaaaag aaaatttagt ccctactttt gctctttttc
    22561 ctggttttac taaagcctgc caagtatctt cctctgttct ttttaataat aaaaactcta
    22621 ttttacctcc agtttcaagc ttctctccta ttaatctagc tggtataact ctagtattat
    22681 ttaatactaa gcaatctcct ggatttaaat attctattat atctctaaat actttatgtt
    22741 caatattacc tgtctcttta tctaatacca tcaatcttga gctagctcta tcttctatag
    22801 gaacttgagc tataagttcc tgtggtaagt caaatttaaa atcacttgtt ttcaatgtta
    22861 aacttcctct cttaaaattt ctccagctac aataatatca aaaaaacaac ttattttcca
    22921 caatattacc ataatctatc aagaaattgc tatttttaac agacaccata tccacaatat
    22981 atagatattt ttccacgata tacatgtctt atccacaata tatagataca atacacacaa
    23041 tttttatcgt gtttatccac agtatctaca gatataatta ccattttgtg gatatgtttg
    23101 aatttttagc cattttagaa atattttaat ttaatgactc ttttatttta taaatactcg
    23161 tataatctat ttttattttt cattaggata tggaattttt aagtgttcat atgctaatgg
    23221 catggctact cttcctctag gacctctatt tataaatcct aattgaagca aatatggctc
    23281 atatacatct tctattgtat ttctatcttc tccgatagaa gctgccaatg tatctaaacc
    23341 cactggtcct cctctaaatt tttctattat agtcataaga agcttctcat ctacaaaatc
    23401 gagacccaaa ctatcgactc ctaaaagttc cagagcatct tttgccacct tatcagttat
    23461 ttttccatca gctctaactt gtgcaaaatc tctaactctt tttagtaatc tatttgctat
    23521 ccttggagtc cctcttgaac gttttgcaag ttctaatgct ccattagact gtatctctgc
    23581 atctaagatg cttgaagacc taagtactat ttttgaaagt tcatcaactg tataatagtc
    23641 caatttacaa ataacaccaa atctatctct aagtggattt gtaagcatac cagctcttgt
    23701 agtagctcca ataagtgtaa atttaggaag gtcaagtctt atgcttctag cagatggccc
    23761 tttcccaatt attatatcta ggcaaaaatc ctccattgct ggatataaaa cttcttcaac
    23821 acttctattg attctatgaa tctcatctat aaataaaaca tcattttcat ttaaattcgt
    23881 aagtatggct gccaaatctc cagctctttc tattgcgggt cctgacgtaa ttcttaaatt
    23941 tacccccatc tcatttgcta ttatacttgc tagtgtagtt tttccaagac ctggtggtcc
    24001 atataaaagc acatggtcta actgctcatt tctcgattta gctgcttcta taaatatact
    24061 aagttgttct ttggattttt cttgacccaa ataatcttct aaagtttttg gtcttaaact
    24121 gttttctata tctatatctt ccatcttcat tgtagaagtt attatcctat tttcatcttc
    24181 aaaaccttgc atttataccc ctcctctcgt acttttgaaa atctacttta tatattttca
    24241 atttacataa actccttaaa tattgtttta aaatccaaat attataaaat ccaaatacta
    24301 tttcaaggat ttactcatta tatatgtaag tgctttcttt ataatagctt ctgtattcat
    24361 accatctttt ttacattttt gaactgcctc ttttgattcc gacaaagtat agcctaaagc
    24421 tacaagtgca tctacagact catcttgtga tatcaatgta ggtttttgtg ataataacgt
    24481 tggttcaaac tctatgttat ttttgtctac cttatcctta agctctaaga cgattctttc
    24541 tgctgtcttt ttaccaacac caggagcttt ggataatttt ccaatgtctt cacttaaaat
    24601 atatgctcct aactgcgctg gtgatgcaaa tgatagtatt gaaagcgcca ccttaggtcc
    24661 tattttagat acagatgtta gtagttcaaa catcttaagt tcttccctac ttacaaaacc
    24721 acaaagactc atatcatctt ctcttacaat taatttagta tatatttttg tggcttctcc
    24781 cacttgtaaa ttcattattg tattggatga tacatttatt ttatatccta tcccattatt
    24841 ttcaacaact atactgtcta tataaatttc ttctactgta ccttttatat aactatacat
    24901 acttaccacc tatattcttt agagtttttt caagtttgtt tgaatgagca tggcaaatag
    24961 ccacagctaa agcatctgca acatcatctg gttttggaac tttttttaga cttaaaaatg
    25021 aagttaccat ctgttgaact tgtgccttat ctgctctccc atatccaact acaccttgtt
    25081 ttacttgaag tggagtgtat tcatatacag gcttcccatt atgagcacat gcaagcatag
    25141 taacacctct agcttgtgca actgttatag ctgtttttac attcttgtta aagaataatt
    25201 cttccattcc aacttcatct atattgtaat tctttactat tgtatcaatt cctttataca
    25261 caagttccaa tcttctcgat atattcatat gggcaggtgt tgtaactgct ccataatcga
    25321 ttgctttaaa cttgctattt ttgtattcaa ttataccata tccaactatg gctatacctg
    25381 ggtcaatccc caatattatc attttttaaa attcccccta aaaataaaag aaataccaaa
    25441 atgtatttct cataaaaact tatgttctaa atcattatat cataaataat attaacaaat
    25501 cataaaatgc tctatgtaaa atataaaatc aaataaaaaa gttatatcaa agcaagattt
    25561 tacctcaata taacttttat atttattaca aataaattat tg
//
LOCUS       DAEQAF010000052        25472 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.054, whole genome shotgun sequence.
ACCESSION   DAEQAF010000052 DAEQAF010000000
VERSION     DAEQAF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25472
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.054"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            48..614
                     /locus_tag="KRN00_002248"
     CDS             48..614
                     /locus_tag="KRN00_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBH1828113.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
     gene            919..1380
                     /locus_tag="KRN00_002249"
     CDS             919..1380
                     /locus_tag="KRN00_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1828114.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            1448..3694
                     /locus_tag="KRN00_002250"
     CDS             1448..3694
                     /locus_tag="KRN00_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828115.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            3687..5519
                     /locus_tag="KRN00_002251"
     CDS             3687..5519
                     /locus_tag="KRN00_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828116.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            6238..7515
                     /gene="hflX"
                     /locus_tag="KRN00_002252"
     CDS             6238..7515
                     /gene="hflX"
                     /locus_tag="KRN00_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBH1828117.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKYALE"
     gene            7748..8245
                     /locus_tag="KRN00_002253"
     CDS             7748..8245
                     /locus_tag="KRN00_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1828118.1"
                     /translation="MDAETLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVQEYSKKVRGMQEKVLQLLFEDFTEKEVEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
     gene            8295..8819
                     /locus_tag="KRN00_002254"
     CDS             8295..8819
                     /locus_tag="KRN00_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH1828119.1"
                     /translation="MKNVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            9131..10495
                     /locus_tag="KRN00_002255"
     CDS             9131..10495
                     /locus_tag="KRN00_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBH1828120.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            10634..11800
                     /locus_tag="KRN00_002256"
     CDS             10634..11800
                     /locus_tag="KRN00_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1828121.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            11917..12699
                     /locus_tag="KRN00_002257"
     CDS             11917..12699
                     /locus_tag="KRN00_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBH1828122.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(12818..13471)
                     /locus_tag="KRN00_002258"
     CDS             complement(12818..13471)
                     /locus_tag="KRN00_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1828123.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(13495..14859)
                     /locus_tag="KRN00_002259"
     CDS             complement(13495..14859)
                     /locus_tag="KRN00_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH1828124.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            15517..16947
                     /locus_tag="KRN00_002260"
     CDS             15517..16947
                     /locus_tag="KRN00_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1828125.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVSMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            17050..18153
                     /locus_tag="KRN00_002261"
     CDS             17050..18153
                     /locus_tag="KRN00_002261"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH1828126.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENKKFVAVLKEILNIKGEPSIG"
     gene            18168..18404
                     /locus_tag="KRN00_002262"
     CDS             18168..18404
                     /locus_tag="KRN00_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1828127.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            18421..19470
                     /gene="vorB"
                     /locus_tag="KRN00_002263"
     CDS             18421..19470
                     /gene="vorB"
                     /locus_tag="KRN00_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1828128.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            19472..20212
                     /locus_tag="KRN00_002264"
     CDS             19472..20212
                     /locus_tag="KRN00_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1828129.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            20215..20754
                     /locus_tag="KRN00_002265"
     CDS             20215..20754
                     /locus_tag="KRN00_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1828130.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            20878..22977
                     /locus_tag="KRN00_002266"
     CDS             20878..22977
                     /locus_tag="KRN00_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBH1828131.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMKKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(23244..23759)
                     /locus_tag="KRN00_002267"
     CDS             complement(23244..23759)
                     /locus_tag="KRN00_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBH1828132.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(23851..25062)
                     /locus_tag="KRN00_002268"
     CDS             complement(23851..25062)
                     /locus_tag="KRN00_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBH1828133.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKCLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
BASE COUNT         9788 a         2924 c         4442 g         8318 t
ORIGIN      
        1 atagtgatat aataataaaa aaatttttaa agagggtgat attacatatg agaaaacttg
       61 aagagatatt agaatataat aaatcatttg tagagaacaa agaatatgaa caatatgtga
      121 catcaaaaca tccaaataaa aaaatagtag tcttatcttg tatggataca agattaactg
      181 agcttttgcc taaggctatg aatttgaaaa atggagatgt gaaactaata aaaaatgcag
      241 gagctactat aatgcatcct tttggaagta ttatgagaag tgttttagtt gcaatttacg
      301 aatttgatgt agatgaggtt atggttgtag ggcatcatgg atgtggtatg tgtaatgttg
      361 atacggataa gttacttggt aaaattttag atagaggaat atctaatgat gtaatactta
      421 cacttcgtag tgctggaatt gatacaaaac aatggttaca tggattcgat tctgcagaag
      481 aatctgtaaa agatagtatt gatttaataa aagggcatcc tttaattcca gatggtatta
      541 ttgtacatgg tctaattata tcacctgaaa ctgggaagtt agatgttgtt gtaaatggat
      601 atgaagataa gtagagtatc ataatgttat ataatcaaga tactgttgaa tatgatgttg
      661 tttcaaaatt tattttggga caactttttt atttgaaaat atatgaaaag gtttatttta
      721 agctttacaa taaaaaatat aagtagctga ctaattaaaa atcttactat tatttattaa
      781 aattataact atatgatata aaaatattta ataaatgaaa tttatatgaa ttttttataa
      841 atatattgaa aaaatgcatg cagtatagta aaataatact tagctgacta agtaatataa
      901 aaaataagga gggcaagtat gaatagcaat tctgaagaaa aattaaatga tgttttcttg
      961 caattaatgc gaatatattt tataagaact catttttatt ttgataaatt aggcttatat
     1021 catggtcaac cccaaatact tttttcttta aagatgaaag atgggcaaag tcaaaaagaa
     1081 ttagcagata aaaggaaagt aaaagcatct acaactacag ttatgataaa gaggatggaa
     1141 aaagctggac ttgtggaaag aaaacaagat gaaaaggacc aaagagtatc taggattttt
     1201 ttaacagaca aaggtttaga aatatgtaat aaagttgaag aatttaacaa ggaattggaa
     1261 agagagtttt ttttaggatt tagtgaagaa gaaaaaatag tacttagaag acttctaatg
     1321 caagtacgag ataatttaaa agcaggatgt cataagcatg aagatgaaaa atatttttaa
     1381 agtttaaaat aatgtttttc aatttaatgt tattagacta attaatatta cagaagggaa
     1441 gaaatgtatg tttaaattaa ttaaatattt aaagaaatcg gcattatcaa tagtaataat
     1501 agtctgtcta ttggtaattc aagcggtatg tgacctttct ttaccagaat acacatccaa
     1561 tatagtaaat gtaggtatac aacaaggtgg agtagaaaac tctgttccat ctgtgattag
     1621 agagagtgaa ttaaataaaa ttactttatt tatggataaa agtagtaagg ataaagtact
     1681 agataattat actttgctga ataaaaagga ttatgttaag tataaagata agtacccagg
     1741 tctaaaagat gaatctcttt atgagttaaa tactaaagac aaagatacta tagatgattt
     1801 aaatgttatt tttggtaaag ctattttaat agtatcaggg cttgagggcg atagtaaaga
     1861 ggtaaaagct atgaaagctc agttaatgag taaacttcca ccacaagcta ctcaaagtgg
     1921 agatgttgat atatttaaat tgttatcagc aatgccaaag gaacagttag atacattgac
     1981 taaagagatg agcaaaggct ttgaaagtat gccagagagt atgataacac aaagctcggt
     2041 ttcatatgta aggtcagaat atgagaaaat aggtattgat acagaaaaaa ctcaaaataa
     2101 ttatatatta tttactggtg ctaaaatgct tggtatagca atgattagta tggtagctac
     2161 aataacagta ggatttttag cagcaagagt agccgcaagt gtaggtagaa atttaagaag
     2221 tggagtattt agaaaagtta tgtcattttc aaatactgaa atgaatgaat tttctacagc
     2281 ttcattaatt actcgtagta caaatgatat tcaacagata caaatgttga tggttatgtt
     2341 gcttagaata gtattctatg cacctataat ggctataggt ggagtgataa aggttttaaa
     2401 cacaaatact tcaatggcct ggattatagc agtagcagta gttgctatct tatcattaat
     2461 tgtagtgtta ttctcagtgg ttatgcctaa gtttaaactg gttcaaaagc ttgttgataa
     2521 gttaaactta gtaagccgtg aaataattac tggtattcca gttatcagag cttttagtac
     2581 tgaaaaacat gaagaagaaa gatttgataa agcaaataaa aatttaacta aaacaaatct
     2641 ttttgtaaat agagttatga catgtatgat gcctgctatg atgcttataa tgaaccttat
     2701 cacagttctt atagtttgga gaggtgcata cagtgttgat tctggagcaa tgcaagttgg
     2761 agatatgatg gcatttatac aatatacaat gcaaataata atgtcattct taatgatatc
     2821 aatggtatct attatgcttc caagagcatc cgtttcagct acacgtatag atgaagtatt
     2881 agtgtcagat ataagcataa aagacccaga aaaatcagag gcacaagagt ttaaggaaga
     2941 taaaaagggt cttgttgaat ttaaaaatgt ttcgttcatg tatccagacg cagaagaacc
     3001 tatattaaca aatatatctt ttacagcaaa gccaggagaa acaactgcct ttataggaag
     3061 tactggtagt ggtaagtcaa ctcttataaa tttaattcct cgtttctttg atgttactga
     3121 aggagaaata ttacttggtg gagttaatat aaaaaatgtt tctcaacatg atttaaggga
     3181 aaaaattgga tatgtacctc aaaagggagt attgttttct ggtactatag aatccaactt
     3241 aaaatatggt agaaaagacg caacagatga agaaatgaga acagcagctg aaatagctca
     3301 agctacagaa tttatagatt ctaaaccgga agcttttaaa actgaaattt ctcaaggtgg
     3361 aacaaatgta tctggaggtc aaaaacaaag actttctatt gcaagagcaa tagcaaaaaa
     3421 tccagaagtt tatatatttg atgatagttt ttcagcactt gacttaaaaa ctgatgcagc
     3481 tcttcgtaag gctttaaaat caaaaactgc tgaaagtaca gttctaatag ttgcacaaag
     3541 aattagtact atcttaaatg cagaacagat aattgtttta aatgagggcg aaatagttgg
     3601 aataggaaca cataaagagc ttctaaaaaa ttgcgaagtt tatgagcaaa tagctttatc
     3661 acaactttca aaggaggagc tagctaatga gtagaatggg aagaggtcct atgggaaaat
     3721 ctatgggagc aggacaaaaa gcaaatgact ttaaagggac tatgcgaaaa ctaattgcat
     3781 atttatctaa atttaaaata tcaataattc tagtaattgt atttgctatt ggtagtgcgt
     3841 cgttttctat agtaggtcca aaaattttag gaaaggcaac tacaaagata tttgaagggt
     3901 tagtgagtaa agtttctgga ggaaacgtag gtatagattt taatgcaatt ggaaaaatct
     3961 taaccttttt acttttcctt tatttgataa gtgcactgtt ctcttttata caaggattta
     4021 taatgagtgg aatttctcaa aaagtatcct ataatttaag aaaagagatt tcagcaaaat
     4081 tggatagatt gccaatgaag tattttgata ctaagacgca tggtgaaata ttatcgagaa
     4141 ttacgaatga tatagatact ttaaatcaaa gtttaaatca aagtatgaca cagcttataa
     4201 catcagtaac aactatgata ggtgttttga taatgatgtt atctataagt ggaattatga
     4261 cattagtggc agttttaata ttaccaatat caatgtttgt aatttcaaga ataataaaga
     4321 aatcacaaaa atactttaga tatcaacaag aatatttagg aaatgtaaat ggtcaagttg
     4381 aggaaactta cagtggccaa acaatagtaa aagcatttaa tcgtgaggat gaagtaattg
     4441 aagagtttga taaactaaat gatagcctgt ataattcagc gtggaaatct caatttttat
     4501 caggtataat gcaaccactt atgatgttta ttggaaactt gggatatgta atggtatcaa
     4561 tcttaggagg ttggcttgca attaagaaaa caattgaggt tggtgacata cagtcattta
     4621 tacaatatgt aagaaacttt acacagccaa tgactcagat tgcacaggtt gccaatttat
     4681 tgcaatcaac agcagcagct tctgaaagag tatttgagtt tttagaagag gaagaagaag
     4741 tccaaattgt tgaaaatgca gtttcaatag atggtttaga aggtaaaatt gattttgaaa
     4801 atgtcaactt tggatataac ccaaacaaga ctataataaa tgatttctca gtaaatgtta
     4861 aacctggtca aaaagttgct attgttggac ctacaggagc aggtaaaact acaatagtta
     4921 aactgttaat gagattttat gatgttaata gcggttcaat actgattgat ggtcataata
     4981 ttaaagattt taatcgtagt gagcttagag aaatgtttgg tatggttctt caagatacat
     5041 ggttatttag tggttcaatt atggaaaata taagatatgg taagttgaat gctacagatg
     5101 aagaagttat agaggctgct aaatctgcac atgttcacag atttattaag acattaccag
     5161 atggatataa gatgaaatta aatgaagaag caagtaatgt ttctcaaggt caaaaacaat
     5221 tattgactat agctcgtgct attttagctg atcctaaaat tttaatatta gatgaagcta
     5281 caagttctgt cgatactaga acagaagtat tgattcaaaa agctatggat aatcttatgg
     5341 aaggtagaac aagttttgtt atagcccaca gattatcaac tatacgtgat gctgatatga
     5401 ttcttgtaat gaatgaagga gatatagttg aacaaggaaa tcatgaggaa cttctaaaga
     5461 aaggcggatt ctatgccaat ctttacaatt ctcaatttga agaagatgaa gcaatgtaac
     5521 aaaaaactat cttagcatag acatgtaatt aataagataa aataaatgag ggtgccttaa
     5581 aatgaacttt ttaattcata aggcactctt ttgtgcatga aataaagtgt atttttatca
     5641 ttttaacaat gaaaaagagg attatctata ttttgagata gccacataat tttatgtctt
     5701 tacaaagtgt ttattttatt ataatatgta gtaaggaaaa tgttggaggt gattatcaaa
     5761 atgtatattt aattttattc tttaaatttt attataaata gaatttaatt ttaatagttg
     5821 atgattatat tgaagtatat gtttttatta cttttattaa tcatgtaaat aactacttaa
     5881 atttaagaat agggttaaat ataaaatgat aattacatat aagttaatta aactaatgta
     5941 tttttaatat atatttagaa ttttaatcct tcttatgata taagtagctt gttttgtatt
     6001 acttagattt gtaaggagtt tttttattga aaaaactgca taatatattt gggaggaggt
     6061 gtaagaaagt gattttttat ataagattga gaaaataatg cacgattatg gttattataa
     6121 tagtaaataa gaagtgtcat ttaaggataa gataaaaagc aaaattcttg atgaatttaa
     6181 ttatagagcc ataatctcgt gctatagatt aaataaaaaa tagcagataa ggagaatatg
     6241 gatatggcga aaaaaggaat aacagtagga ttaaacataa ataataaatc tgaggacttt
     6301 aatgaactaa tgattgaact tgaaaactta tgttcagcat gtgatattga tgttgtaggg
     6361 agtataactc aaaatgcaaa gcaggttaat agagcatttt acattgggac aggtaaagtt
     6421 gaggaaatat taaacttaat aaagaaagaa aatatagaga tagttatatt ttacaatgaa
     6481 ctttctacat cacaactaaa aaatcttgaa gaaaagctta attgtgaaat tatagataga
     6541 acggcattga tacttgatat atttgcacaa agggcaaaaa ctagagaagc taaacttcaa
     6601 gtagaagtag caagtttaaa atatatgtta ccaagactta taggttcaaa tgaaaattta
     6661 ggacgtcaaa gtggtggagt tggtactaaa aatagaggtt ctggtgagaa aaaattagaa
     6721 cttgaccgta gaagaataga agaaaagata acatctttaa atagggagtt ggatgattta
     6781 aaattccaaa gagaaactca aagaagtatg agaagaaaat caaatcttcc aaatgtagct
     6841 ctagtcgggt atacaaatgc tggtaaatct tcaataatga ataaactagt agatatattt
     6901 aaaaactctg aagaaaagaa agtgtttgag aaaaacatgt tatttgctac acttgaaact
     6961 tctgtcagaa atatagttct tgcaaataac aaagaatttt tattatctga tactgttggt
     7021 tttgtaagta atctaccaca tgacttagta aaagcattta ggtcaacatt agaagaagca
     7081 tgtgaggcag acgtactgtt acatgttatt gatatttcaa atccaagcta taaaagtcat
     7141 attaaagtga cagaagatac tttaaaacaa ataggtgcag atggtatacc tatgatacat
     7201 gtgtataata aaattgattt aatagatgta gaagtattgg atagaatttt agatagtatc
     7261 gataaagaag gtatatttgt ttcagttaaa aaagatataa atatagataa aatgataaaa
     7321 tgtatttgtg atagcatatt taaagattat gtaagatgta agttcttaat tccatatgat
     7381 aaaggtcatg tagtttctta ttttaacgaa aatacgagca ttataaatac agaatacaga
     7441 gaagatggag ctattttaga tgtagaatgt agcaatatag aatataataa gtataaaaag
     7501 tatgctttag agtaaatttt gaaaaactta ttatagccta aaatatattt aatttataat
     7561 ttattataaa ttgattgtaa atatgatttt atgaaacggt atagccataa tgctatgccg
     7621 ttttgctatt tataataaaa ataaatttat tgacataata gtaactaatt actataatat
     7681 aaagtaacta gttactattt aaaattatca aaaaattaaa atctaagata aagagaagtg
     7741 tataataatg gatgcagaaa ctttaatgaa aaaatatatg gtagatgatg atagtagaaa
     7801 acaagctata tttgcaagta tatttgtaat gcaaaataaa cttcaaacta catgtgataa
     7861 attagaccca gaattaacaa tgaaacaatg gttactttta gctattgcgg actctgtaga
     7921 tgaaactctt acattaacca aacttggaga attaatgggg tgttcaagac aaaatgtaaa
     7981 aaaactagct attgctttag aaaagaaagg ttttatagaa attgagcaaa atgaaaaaga
     8041 ttcaagagct atctgtcttg tgacaaaaga tagagtgcaa gagtattcta aaaaagtaag
     8101 aggtatgcag gaaaaagtat tacagctttt atttgaagat tttacagaga aagaagtgga
     8161 acagttattt tttggaatta tgaaattaag tataggaatt gaaaatgtga aaaattatgt
     8221 agaaaataat gacgttggag aataagcaag tatcaaatca actttgtatg acatcagaga
     8281 ggggggtaat ttatatgaaa aatgtagtag tgatttataa gagtaagtat ggttcaacaa
     8341 aaaaatatgc taaatggctt tcagaattat tgtcttgtga tatttttgaa actaagaata
     8401 ttaatataga aaaggttatg aagtatgata cgattatttt aggaggaggt ctttatgctt
     8461 gtaatatagc gggaatttct ttcttaaaaa aaaattataa agaattgcag aaaaaaaatt
     8521 tagtagtatt tggcgtagga gctgctccat atgatgatga agtaataaag aaattaagag
     8581 aagtaaattt taaggatgaa ttaaacaaaa ttccttgctt ttattgtcgt ggggcatggg
     8641 atgagacaaa aatgtctttt atagattata ctctttgtag tttttttaaa aaatctatag
     8701 ctaaaaaaga acgtcaaggt cttaaaccag cagaagcacc tttattgtct ggagaagcct
     8761 ttgattggtg taataaagaa aatttaactc caatacttga ttatataaga gaactttaag
     8821 aggtatatat ttgtaattat ttattatcta aagttagatt tcatagaaat ttactagaca
     8881 ttatttataa aataatatta ttaaagatgg ataatttaat tgtttcaata aggttataat
     8941 tttaaaaaat gtttatttta aaataaatta ttttataagc ttacttatac ttaataaggg
     9001 gcttttttta ttggaagatt tatgttatat tgagatgaat ttattatgat ataaaaaata
     9061 atgttaggat aaatttaaat ctttttctaa aaatgtatta gtataattct taaagaaagg
     9121 atttttaaca atggatataa aagagttagt taaaatgcaa agaaaatatt ataatacagg
     9181 taaaacaaga gatatatcgt ttcgtataga acagttgaag aaacttaagt tagttgtatc
     9241 acaaaatgaa gaaaaaatac ttttagcact aaagaaagat ttaaataaat cggattttga
     9301 aggttttatg acagaggtag gcatgtttta tagtgaatta aactttgcta taaagaatat
     9361 aagaaaatgg agcaaaataa aaagagttaa atcaagtatg gttaattttc catctatatc
     9421 caaagttgtt ccacaacctt atggtgttac tctcataatg tcaccttgga attatccatt
     9481 tcaattagca cttataccat tagtttggtc attagcagca gggaattgtg ttatattaaa
     9541 accttctgaa tattctgtgt caacatctag tgtagttaaa gacatagttg aagatacttt
     9601 ttcaaaagaa tatgttgcag ttgttcaagg aagtcaagaa gaaagtgaaa agttactatt
     9661 ggaaagattt gattatatat tttttacagg aagtactaat gttggtaaaa taatcatgaa
     9721 atcagcatca gagcatttaa ctcctattac tttagaactt ggaggaaaaa gtccttgtat
     9781 cattttaaaa gatgctaata tagaccttac tgccaaaaga cttacttggg gaaaactaat
     9841 aaatgcagga caaacctgcg tggctccaga ttatgtttta gtgcatgaag atagaaaaaa
     9901 tgagttaata gagaaaataa aatattatac taataagtat tttggggata atgcatgtaa
     9961 taatgagcaa tttcctaaaa tcataaatca gagacatttt aatcggatat tatctcttat
    10021 tgataaagat aagatagtct atggtggaaa ttataataag gagacattaa agatagagcc
    10081 aactatagta gacaatgtta attgggatga taatataatg aaggaagaaa tatttgggcc
    10141 tatatttccc attttaacat ataaagattt agatgaagta atacaaaaaa ttatacaaat
    10201 gccaaatcca ttggcacttt atatttttac aaaaaataag tacctagaaa ataaactttt
    10261 agaaatgatt ccagcaggcg gatgttgtat caatgataca gttactcata tagctacgaa
    10321 ttacttacct tttggtggta ttggtgaaag tggtatgggc tcatatcatg gaaaagctgg
    10381 attcgataca tttactcact ataagagtgt gttaaaaaaa ttaaatttgg atgtccctat
    10441 tagatatgct ccatacgata ataaattaat taaggttctt aaaaagataa tgtaggttat
    10501 attgtagaat aataaatata aataaaattg agtatttgta ttctgaatat attttatttt
    10561 taatttggta tatttgttat aaaagtggtg attttgtgat aaaatttaat tatatagaaa
    10621 taaggaggaa aaaatgaaaa ttaattggaa tacaaaatac acaacaatag caatttatac
    10681 atttataata gctgctagta gtattatatt ttatctagta tcatcacaaa ttgatgtatt
    10741 ttctaataat ttagatgcta tatttacaac attacaacct tttataatag gatttgctat
    10801 tgcatatctt cttaatttta ttttaaagtt ttatgaagac agaattttta taaaaagtga
    10861 gaaattaaaa aaactaaaac aaagttcaaa aagaggcttg ggtcttttat taacatatgc
    10921 aacagctaca ttgatacttt acttatttat gcatttcgta ttgccacaag taattgagag
    10981 tattgttgga ctagcaaatg atatacctat gtatgtaaac aatgcaacta agcttattga
    11041 taaattaatg actgatttaa atcttgatga gcaatacttt aatttggcag ttgataagtg
    11101 gaatgaattt gttacatata ttataaagtt tgtaacagat ttaatcccaa tattaggaag
    11161 tatgttaaag aatgtagcct ctagtatatg gaatattgta ctaggattaa ttgtttcagt
    11221 gtacttatta attgataaag aaaaattcta tggattaagc aaaaaaataa cttatgcagt
    11281 atttacagaa aaacaagctg ccagaatttt agaattaact catagaagta actatacatt
    11341 tggaagattt ttaggtggca aaatattaga ttcattcatt ataggtattc taacatttgt
    11401 aatacttacg ttagttaaaa tgccatatac attattaata tcagttataa ttggtattac
    11461 aaatattatc cctttctttg gacctttatt tggagctata ccatctacgc taatagtgat
    11521 gtttgtatct cctataaaag ctttctggtt attgttgatt atattaataa tacaacagat
    11581 agatggaaat attataggac ctaaaatact tggagattca attggtatat ctgcattttg
    11641 gattttgttc tccttattgg ttgcaggaaa attattaggt tttattggaa tggttatagg
    11701 agttccaatg tttgcagtaa tttattctat aattaaggat attgttgaaa gtaaattgga
    11761 caaaaaggga ttaccgacag atacttccga ttatatgtag ctaaaaaata ttatgtataa
    11821 ttaaaaatat ataaattaag caatatttaa agcactgaga aagttaaact cttggtgctt
    11881 tttagatata aaattattat agaagaggtg ttttttgtgg catttataga atgtaaattt
    11941 aaatctaaat atactggagg agaaactgat ataattgtaa ttttgcctgt agcaaatgga
    12001 aaagaacttt ttagtggtaa agagatatat gattttgaag gtaaatttaa aacattatac
    12061 ttatttcatg gtttagaaga tgaccaaagc tcatggatta gatatactaa tgtagagcat
    12121 tatgctaaaa ataaaaatat agccctagta ataccaagag tagaaactag tttttatact
    12181 gatatggcgt atggacacca atattttact tttgtaagcg aggaattacc taaatttgtt
    12241 agagctatat ttcctttatc agataaaagg gaagataact ttgtagctgg tatgtctatg
    12301 gggggatatg gagctttaaa attagcgctt tcaaaaccaa aagagttttc ggcagttgca
    12361 agtttttctg gttcgcctga tatgattcat gagttagaaa atcaacaaat agaaaccaat
    12421 gcagacattc tatttcacga ttttggtaga ccagaagacg ctagaaatag tgagaatgat
    12481 ttactttaca tacttaagaa ccttaaagaa agaaatgaag atattcctaa aatttatcaa
    12541 ttttgtggtg atagagattt tttatataaa aataatcaga tgtttaaaaa atatgcagat
    12601 tctctgggtg tagatgttga atatgaagag tgtgtagggg ggcatgaatg gcgtctttgg
    12661 aatttatgga taaagaaatt tatagatata attggatagt acacttatgg tattaacagg
    12721 tatactataa aatatcttta aatatgataa agactgaaat cctaaaatca aattatgatt
    12781 ttaaaatttc agtctctaag aatttaataa aattttatta agttcttaca cgagttatta
    12841 ttggagtaaa attgtcaact atatctatat agtatttact caattcctct aaaatctctt
    12901 cgcataaatc cgtactatga ccaagattaa taagaaactg ttttgtaaaa tgctttatta
    12961 cagcttgaga agatatatcg tacttgtgtg aagtataaac tctaattatt tcaggtttca
    13021 tagcaagtat accaatacaa gaaagtatta attcatcatg ttctatagat tctttatcat
    13081 taacatatct tttcatgacc atttcggtta cacttctttg atagcttaaa atagcttctt
    13141 cataagctat atccaaataa aaatttctat atgcttcgtt ttttagaagg aaacaaaggt
    13201 cagcattcat agcaagaaag aacatcatca tagtaccttc ttcatggtag ttatagatta
    13261 aagactgcat ttcatttctt atatcttcat atattatagc tcctatttcg cttttacttg
    13321 agaagtaata gcttattaga cctaaattta tattagctct ttctgcaatt tgcctagttg
    13381 ttgtcttatg ataaccttgc tcaaaaaata attctctagc agcacttata atactagctt
    13441 ttgtttcttt gcccttttct gattttgaca tatttactgt gtatacctct cttttcaatc
    13501 tttttttgaa aatttgctaa ctataaatat tgtaatagaa ccacctatta taggaaccaa
    13561 aattctgtca aatacagtaa gaataccaat catatttaat aatgccaata taacacttac
    13621 tataacagca tagatagctc ctttttttgt agcacctttc cagcaaagac caattacaaa
    13681 tggtgcaaat attacacctg tacataatgg agccggccaa aacaataatt ctaataaact
    13741 atcaaattta agtgctatga ttgcacctat tatagctgtc aaagctgatg caatttgaga
    13801 atactttaga gtatttttta aatcattaaa ttctatatta ggatgtaata atttgttata
    13861 aatatctctt gatataatag cactcattga ggtcattaat gaatcggcag tagacattat
    13921 ggcagccaat atagcagcta agaataatac agatattaaa ggtggcaaag tagtcgatat
    13981 catttgaggt aaaacctgaa cagatgatat atttggaaat aaactaccac caatagctcc
    14041 aattattcct atagggaaag caagaaataa tagtataaat cctgcaatta cactactttt
    14101 aactgcattt ttagcattat cagcacattg atatcttaaa aaactttcat aagaaaatat
    14161 tgagcctaaa actaatggta aaactgtata cataaaatca ctaatcgatt tatttcctgg
    14221 aaagaatggt tcttttacca ttgattgtaa cataagtaaa gggttgtcgc caactaattt
    14281 taagcttata taagctacta ttggcaaaaa cactatacaa atagcaagtt gaataaatgc
    14341 tgatactgca actccccaca ttcctgatgt ataagtatat ataatgataa ctataactcc
    14401 tataattaca gctatatcat aaggaatacc aaatgcagta gatacagaac caaaagaaat
    14461 taattgacta cccataatag ctagtataga tattggtgtt acaagacttt gataagctct
    14521 taaaaataca ctatgaccat atctagtttc aatataatca gcaggtgtta tatcacaaga
    14581 taagcttctt aattttcctg cgaaaaatgc atttataaag caagctaaag ctgcacctat
    14641 agtagaatac attccaaccc aaagtcctct ttcagctccc cattgaactc caccaactaa
    14701 gcaccctcct ccaaaagatg tagcagcaat ggttgcagct agtataggca aaggcagatt
    14761 tctacctgcg attaggaaat cggatgctgt tttaactttt tttgaaaaat aaaaaccaat
    14821 ccatatgtat attgcacacg taacaattaa aagtaacata gtcttttctc ctttataaaa
    14881 tattttaata aaatatacaa aatatattta aaatatattt tatataaaag tagtacgata
    14941 tttgttttat tggttttaga ttaatatagc tataataatt tatgatatta gatggaaatt
    15001 acgtaaaaat agaaaattga aaattctgaa atttttgcat attgatattt atctcataga
    15061 ttcttttttg taattgtaac acgcttttat ttttaaatca atagtacatg tataaaaata
    15121 aaaggaattt aaataagaaa aagatatttt taatatctgg atgtagtata gaaatatctt
    15181 gaataaatta ttcttgaata aaattataaa aaattaaaat cactagaaat atgataaaat
    15241 aatttaaaat atgcatttca atgacatttc aaaacaagaa aataataaaa aacaaaccta
    15301 aattaagcct aaatagcttt ttagttaatt ttagtagtaa aaaataaaac ttaaaaagtg
    15361 tttgacaatt atgaattttg agaatataat taaattaaaa ttatacacat ataaaaatat
    15421 actcctgaat caagaatgag atatttaaga ttcaaaatat atattattat acgtgaataa
    15481 taaaaagtaa gaaaatttta taagggaggg gtagatgtga gtagtcaaga aagcaaacca
    15541 aaaggaaatc ttatatcaaa ttttagagat gatatgagag accctaagaa aagagcaata
    15601 tacacatatt caagttctat aaacttagcg tacaatttta taggttactt tgtatcaact
    15661 gttacaaata tttttttaac tgatgtggca aaacttggtg taattatggc aggtggtatg
    15721 caaattatac aatctttcat aaaaattgct gtagctccta taacaggtac agtatttgac
    15781 aaacaaccat tcaaaaaagg aaagtattat ccatggctta gatatgcacc agcagcgtta
    15841 gcattaacat atggaatatt tttcatagtt ccattaatga aaataagtcc agcattactt
    15901 ttacctttga tgacagcttt attattaata gcatcttgtg ctcagcaagt agttttcact
    15961 ataatttatg ctatttaccc tgtagttgct aagacaccta gagaccgagt tataggctca
    16021 actactacga atatatttaa agaagttggt aaattcttag taggtttttc atatccgtta
    16081 ttattagttt tatttgcaga tgtattaggt ggagaaggaa tgggttattt aggtacctac
    16141 ttattctttg cagcagggtg ccttttagta ttttggtttt cttcaacaga gataataaaa
    16201 tctggagcag aagaagaagt tcttcaaaaa gaagagaagc caaagattaa agcaagtgaa
    16261 atggcaaaag ctttattcac taatgtacca cttatgatgg cattttgttt agaatttctt
    16321 atatgtataa gatctatagg attaggacct ttggctccat attattttaa atatgtaata
    16381 gaagatgaac gtggattagc agtattttta tcaatcatgc ctttggtaag tgtagcattc
    16441 atgtttttcg caccagtgtt tataaaaatc tgtagagagc aaaaactagc ttcaataatt
    16501 tctttttcta tatgcgcatt atgccactta ttggttgcat ggactccttg ggggaaaact
    16561 actttaggag taactatgtt gctggcaatt ggtggaggtt tttcaaatgt agtatcaata
    16621 ataaatctta atttctttgc cggttcttgt gattatgggc attggaaatc aggaaaagac
    16681 ttgcctggct taagtatgtc actatatcca gttgcaatac aagtaggagt attacttgca
    16741 actactataa gaacagtttc aatgaactca atgggatatc aagctgatat ggtagtcaca
    16801 gaagcagtta aatcaggttt tataaatatg atttcttatt ctatggcaat acctttaata
    16861 atagctgttg ttatagcaat actatatcca gtaagtgaca agaaattaaa ccaaataaga
    16921 gaagagttaa atcaaagaaa tgcttagtta aaagaaagtt gagtagatgg ttaatttaag
    16981 ctattaaagt aagtagacgc aatagcgttt atataaatga aaatacatat acagaggggg
    17041 cttttaaaaa tgatagaaaa attattgaga aataccgtaa aagaattaca tcaatatgtt
    17101 ccaggtgaac caatagaaaa agttaaggaa aaatatggtg taaaagaaat aataaaatta
    17161 gcttcaaatg aaaatcctct aggaccatca ccaaaagcaa tagaagctat gattgaaatg
    17221 ttaaaacaag gtcaacttta tccagagcca gaagctaacg aacttagaag aaaattagct
    17281 gaaaagctag atttaaaacc agaaaatttt attgttgcta atggtgcaga taacgttatc
    17341 actctaatcg gtgaggcttt tataaataga ggagatgaag ttatatattg taacccaaca
    17401 tttccatcat atagaactgc aactataaaa aatgaaggga taccagtaga agtaccttta
    17461 acagaagatt ataagtatga tttacaaggt atattagata agattacaga taaaacaaaa
    17521 ttaatatgtg tatgtaaccc taataatcca acaggaacaa ttgtggatga taaagagtta
    17581 gaagaatttt taaagaaagt ccctgaaaat attataacta tattggatga agcatatata
    17641 gaatttttaa cagttcctaa ttatgtggat ggacttaagt atgtaaggga aaattataac
    17701 gttatagtaa caagaacttt ctctaaaata tatggtcttg cagggcttag agtaggatat
    17761 ggtattgcta aagatgagat aataagaact ttatttacag taaaagagcc tttctctgca
    17821 aatcgtgttg ctataagtgg agcaacagca gcacttgatg atgaagagtt tataaaagaa
    17881 acatatgaat taaatagagt tggaatggct tactttaaag aagagtttac aaaaatggga
    17941 tttgatgttg tagattcaca atcaaatttc ctttatgtag atatgaaaac agatatacct
    18001 aagttatttg aagacttgaa aaaaagaggg tttgtaataa gaccaagtgc tacacatgca
    18061 cgtgtaagta ttggaactat ggaagaaaat aagaaatttg tagcagtttt aaaggaaata
    18121 ttaaatatta aaggagagcc aagtattgga taatagatag aaatattatg aaacggggtg
    18181 tagatatgaa cttaaaaata aacgcagaga gatgtaaaag ttgtgaatac tgcgttatat
    18241 cttgtaaaaa aggagcatta aaaatatcaa gtaagataaa caaagaaggt tatgctcatg
    18301 tagaagttga tgagagtaaa tgcatacttt gtggaatttg ctatcaggtg tgtccagata
    18361 atgtttttga aataattaaa gaagaagcat gtcaagaggc ttagaaggag ttgggataat
    18421 atgaaaaaga tgtggaaggg gaaccacgcc attgcagaag cagccctaag aggaggttgt
    18481 gaattttatg caggatatcc aattacacca caaacagagg taatggaatt tttatcacat
    18541 agaatgtctg aacttggaag aacttttata cagtccgaaa atgagatggc agctatatat
    18601 atggtatatg gagcatatgc aagtggaatg aggtctatga cgagttcttc aggaccagga
    18661 atatctttaa aacaagaagg gatttcttac ctatgtgcaa atcattaccc ttgtgtaatc
    18721 gtaaatgtac agagatgggg gcctggtctt ggctcattgg actcagcaca gacagactat
    18781 ctaagagata ctagaggggg aggaaatgga gattatcatt tgatagttta tgcaccaaac
    18841 agtattcaag agactgtaga tttgatgtat aactcatttg atgtagcgga gaagtacaga
    18901 gtgcctgttg aaattttgac agaagcagct ttaggtcaaa tgatggaacc agtagaattt
    18961 ccagagttta agaagagaga aggagattta ggctggactt atgatggaag taatagagac
    19021 catgcaaagg ttgcagataa ccaaaagcca actttttgta tggagaaacg tatgagaata
    19081 actgaaaatg aacaacaatg ggaagattat caagtagaag atgcagaata tgtgtttgta
    19141 gcgttcggta taccatcaag aacaactatg aatgctgtta gaaggcttag agaacaaggt
    19201 gaaaaagttg gaataataag accaataaca gtatggcctt tcccatataa agcatttgaa
    19261 aaggtaagta aagatgtaaa aggatttatc tcagtagaat caacagacac aggtcaatta
    19321 gtagaagatg ttgctttagc ctcaaagaaa gtatgtaaag aaaatgtacc tgtgtatggt
    19381 ttatttagtg gaaatcatat accaaaaaca ttgcaagtaa tggacactta tagcaaaata
    19441 aaatctggcg aaatcaagga ggtgttctaa tatggctaca gaaaaattaa cacctagcgt
    19501 tgtttcaata ccaaacaagt tttgcccagg ttgtggtcat ggaatagtaa atcgtataat
    19561 agcagaggta atagaagaac atggatatga aaaaaatcat gtattaacat taggagttgg
    19621 ttgtgtctgc aatatgaatt ttagctggaa tggtgataag atgcaaactg cgcatggtag
    19681 agcttcatct acagctatag gagttaaagt agcacttcca gatacattag taatgactta
    19741 ccaaggtgat ggagatgctt atgttatagg tctttctgaa actttaaata cagcatatag
    19801 aaatcataat gtgactgtat ttgtaataaa caataataat tttgcaatga ctggtggaca
    19861 aatgtcatgg accactatgc cgggtcaagt cacaacaaca agtgtaaatg gaagagatat
    19921 aaagactact ggtagtccac tgaaagttcc tgagatggtg gcaaacttct ttgatgtagc
    19981 atatgtagca agaggttcag ttcatagccc aaaggaaata attaatctaa aaaaatatat
    20041 aaaaaatgca atagaagctc aattaaatgg agagggatat tccttagttg aaatattagc
    20101 accttgccca actaactggg gtgtatcact agagaaatct atcaaatgga tggaagaaga
    20161 aatagtgcca tattatgctc ttggcgaatt taagcaaagg gatggtgaat agttatggaa
    20221 aaagagctag tatttgcagg gtttggtggt caaggagttt taactcttgg tctgattgta
    20281 gctgagtcag cacttgaatt ggggaaacaa gtaacttgga tgcctgcata tggtccaact
    20341 atgagaggtg gaaaagccta tagtgtagta aagttttctg atgagagtat aggtgggcct
    20401 gatatggaag aaatagatgt tttagtagca atgaataaac catctttaga ttatataaat
    20461 ttagttaaag aaggtggaac agtagttatt aatacatctg caatagatga gaatgtaaca
    20521 ttaagagaag atataagtgt agttaaaata aattgtcagg aattagctca aaaagtaaac
    20581 aatccaaaag cagcaaatat agtagtactt ggagcattaa ttgctaaaac tgggttattt
    20641 gaaaaagaat tagctttaaa aactatgtgt gatttctttg aggaaaaagg aaaaggaaag
    20701 tttaatgttc aaaatgaagc agcattcatg gaaggctata ataacgccat ttgataaatt
    20761 acccttatct taagtgattt atctcaagat ttaataatct ttagtgccaa gagaaacttc
    20821 atcttgagat aaaattcact taaaatcaca actataaaca tataggagcg tgaatttatg
    20881 agtttggaaa aacttattag accaaaaagt attgctatag taggagtgac tgataaactt
    20941 ggttttggaa gaagtgcagc acttagtata gtaaaaagta aggaaacaga tagagtatat
    21001 tatgttaatc ccaaaagaga agaattgttt gggagaaaat gttataagac gatacaagaa
    21061 gttccagaag tagtagactg tgtagtagta tgtacgccta gaaatgtagt tccatctgta
    21121 ttaaaagatt ctggagagtt aggaacaaag gcagcagtgg tatatgctag tggatttgca
    21181 gaggaaggta cagaggaagg tacagattta gaaaatcaac ttatagaaat atcaaataca
    21241 tacgatatga aaatattggg tccaaactgc atggggttgc taaattgtat agataaggtt
    21301 aatctatggg caggaggttc taaatgggat ttagatacta aaaaacctgg tataggaatt
    21361 gtaggtcaaa gtggatttat aactgctgaa attgtttcaa gtgattattt taatatatct
    21421 tatggttttt caacaggaaa tggaaatata gttacactag aagatgcagt agatttcctt
    21481 gtagatgatg attatgcatc agtaatagca atttaccttg aaggtttaaa aaatcctcaa
    21541 aaatttatag atgctttaaa aagggcagca caaaaaagaa agccagtaat aatattgaaa
    21601 tcaggaaggt cagaaaaagg tgctatttct gctgcttctc atacaggaaa tctagctggt
    21661 tcgagtaaag cttttgaaag tatttttgaa aaatatggag taatttctgt ggaaaattta
    21721 gaacagttta tgtgtttagc acaagctttt agtgttttag atggtaattt acctgcaaat
    21781 tctaattttg cagcaataaa cttctcagga ggagaaaata ctatttgtgc agatttagca
    21841 gaagaaaatg gtgtagaact tgcagaaata tcttctgaaa ctaaagaaga aatgaaaaaa
    21901 tatcttccag gatttgcaac acctaaaaat ccactagatg ctacaacagc attattccat
    21961 gaaaaggata tgatagtagg tttattacat acctttgaaa aggatgatag tgttggattt
    22021 actatggtag gtgcaaatat aagagatgaa gaaaatgaaa tgcatgaaac cctttgtaaa
    22081 gctgtaagtg aagctagaga acaaggattg aaaaaacctg tgtttgcagt tcctacactt
    22141 gaaggaaata gatatttaga ttataggact agattagaag ataatcaagt gcctataatg
    22201 tcatcagttg gaactacatt tacttgtttt aataaaatgg ctaagtttat agattatgat
    22261 tattctaaga gaactttaga atttaaagct gttaagaaaa gagagtcaaa taatgtagta
    22321 gcattatcag aattagatag taagattgag atgaaaaaat atggagtacc agttccagga
    22381 caaggtaatg caaaaagtat tgatgaatta gatgaaatct taaaatatat taagtatcct
    22441 gttgttttaa aaataaattc ttctgaaata ttgcacaaat ctgatgttgg aggagttaaa
    22501 ataggaatta agaatagaga tgaggcagta gatgcatata atgagatttt aactaatgta
    22561 aaaaaagcaa aaccagatgc taatattgat ggtatattag ttcaagaaat ggtagaaagt
    22621 ggtatagaaa ttattattgg tataactaat gatgaccaat ttggaccaat gttattagtc
    22681 ggtttgggag gagtatttgt agaggtattt aaagatacta cattatatcc attacctata
    22741 aatcatgatg aagctattat gatgcttaaa aaactaaaat catttaagct tttaaatggc
    22801 tatagaggaa gtgagccttg cgatattgat gctcttgcag atatgatggt caaattagga
    22861 aaatatgctt atgaaaataa ggatgaagtc aaggaaatag acttaaatcc agtgtttgta
    22921 tatcctaaag gaaaaggcgt atgtgcagta gatgccttaa tagttaaata taaatagttt
    22981 ataagttttg gtattcaacc ataattaaag caccgactga aaatcacatt ttgtaagtta
    23041 gatagtgtga ttttcagtca ccccaaattt aatttaaaaa tattttaaaa tgaaagtata
    23101 gttttaagtt tcattgtgaa atagcactgt ataaacaata aaatactacg tataaaacga
    23161 ataataaaag gtgttttaat gataagaatc aatcttgatt ttcattaaaa caccttcttt
    23221 attatattaa aaatttttaa acgttatatt gtcacaggtg ggtttgttgg agctgcatat
    23281 gtacgattag caaattcttg gtcaacaaag aatagaccac cctctccagc aagtttaaca
    23341 cgttttatat tgtcttcaca atttgtttct tcttctgctt gttcagatat aaaccaaagt
    23401 aagaattgag aagttctaaa gtctgattca gagtttgcta cagctgctaa gttgtttatt
    23461 aaagctgtaa cctttttttc atgagctaac gtacgctcaa gaatatccat tgcagaagta
    23521 aagtctgaat ctggcattgg gatagcatca agctgaacct ttcctcctac attatgtaag
    23581 tatttgtaaa aaaacatagc gtggtctgtc tcttctttat attgaacata aaaccaatta
    23641 gaaaatcctt taagtccttc tgcttcaagg taagaagaca tagaaagata aagatacgca
    23701 gaatataatt catggttaat ctgctcatta agtaattttt ccattttagc tgaaatcatt
    23761 tttatacctc caaattttaa atgctcttat aaaatataat aatattaaat ggaaaaatat
    23821 tcaataaaag tgtttaaata ttttacatat ttaataaaaa tttatactac cattaaaaaa
    23881 attataactt acaatggcta tagagccaat taatggtgca tttgctccaa aatttgaatg
    23941 ccttacactt atttttttat atttagaaaa acttgctgaa gcagtcaatt tttttaataa
    24001 tgtattttct ataaatgtac caggtatatt aaagtcatag cctattatta tagaactaca
    24061 atcaatcaat gtaagtgtat taactaatgc atatgatacg tatgtacaaa attcatcaag
    24121 caaaaacatg gcaagactat ctttattatt tgcctcatct attaacttga ctaaagaaaa
    24181 atctttacag ttaattaatg gggagttagg ataaatatgg ctcaatgatt caattctttt
    24241 aattagatta ctgacacttg tataataatc taaacatcca ttgttaccac aactgcacaa
    24301 tggtccacta aaattaattg atgtatgtcc tatttctcca ctttgtccta ggttgccagt
    24361 atgaagttta ttttctagaa ctagaccagc tccaatacca ttcattatat gtaggtatat
    24421 ataatttgat atatttttac ctaaaccata cattttttct gctaatgcac ccgaattagc
    24481 atcatttatc aaaaatattg gcaaatcaga catttctttt ataaaatcta ctatatttag
    24541 gtttgataca tttccaaaat ctgggggatt tagtatggta ccatttatat catctactgg
    24601 acctattgaa gaaataccaa ttccaattat atctctcttg ttgattttca ttattttagt
    24661 aaacattctt tttattatat cttttaaaac atcatttgat agacatttgg ggtaagtttc
    24721 agaaagttgt tttacaatat taccttttaa atctgaaata attaccttac atatatttct
    24781 tcttattagg attccacaaa tacaaggcga tatattagaa atatctaata aaataggttt
    24841 acgacctgat gaatgtgcat ttaaagttga tgactctatt tccctaatca tattttcatt
    24901 aataagttca gtaactagat ttgataaagt cattttagta agtcctgtag acttagctaa
    24961 atcaactctg gacataggtg tatttgtaga aagtaatttc aatattatta acttattttt
    25021 aatttttaca tctttgatgt tagaaccttg tttgttactc atcataaatc tccttaaata
    25081 aagttaagtg ttttatttat tttcaagtat actatcacct tataatagag taacattttt
    25141 ttacttgaaa atatcattaa ttagaatata tcacattata tatcataaaa tatataaaaa
    25201 aatgttagaa ttaaattaaa agtgaaaagt agattgatat ataaatagta aatacttaat
    25261 taaaaaaaga taatgatagc aataattatt gttaccaaga atctactact tcaagtgtta
    25321 ccttaggtat ttaagttgat agtggtttgc acgtaataaa cttgatgtaa tatatattct
    25381 taataatatc gataaaagat ttacttaaaa ataatataga ttatgtaaac atataatcta
    25441 tttattgtat acaataaaat ttcattttgt aa
//
LOCUS       DAEQAF010000053        24606 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.055, whole genome shotgun sequence.
ACCESSION   DAEQAF010000053 DAEQAF010000000
VERSION     DAEQAF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24606
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.055"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            615..1127
                     /locus_tag="KRN00_002269"
     CDS             615..1127
                     /locus_tag="KRN00_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828134.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLDDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     IYNYFDELEK"
     gene            complement(1841..2938)
                     /locus_tag="KRN00_002270"
     CDS             complement(1841..2938)
                     /locus_tag="KRN00_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1828135.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRY
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            3231..4757
                     /gene="glpK"
                     /locus_tag="KRN00_002271"
     CDS             3231..4757
                     /gene="glpK"
                     /locus_tag="KRN00_002271"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBH1828136.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            4798..5913
                     /locus_tag="KRN00_002272"
     CDS             4798..5913
                     /locus_tag="KRN00_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBH1828137.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLIFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(6194..6958)
                     /locus_tag="KRN00_002273"
     CDS             complement(6194..6958)
                     /locus_tag="KRN00_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBH1828138.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYIKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            7217..7307
                     /locus_tag="KRN00_002274"
     tRNA            7217..7307
                     /locus_tag="KRN00_002274"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7251..7253,aa:Ser,seq:gct)
     gene            7395..8183
                     /locus_tag="KRN00_002275"
     CDS             7395..8183
                     /locus_tag="KRN00_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBH1828139.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            8204..8944
                     /locus_tag="KRN00_002276"
     CDS             8204..8944
                     /locus_tag="KRN00_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBH1828140.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEPGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            9120..9494
                     /locus_tag="KRN00_002277"
     CDS             9120..9494
                     /locus_tag="KRN00_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828141.1"
                     /translation="MGNKNKNTKYKDKTRERYNKKVENLNKEKLNKINKQSKKVDKID
                     DIINKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVK
                     ALFSIFVIVCFLIAFKYVVNPV"
     gene            9586..11046
                     /locus_tag="KRN00_002278"
     CDS             9586..11046
                     /locus_tag="KRN00_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBH1828142.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFENFKAELENAIKK"
     gene            11099..14128
                     /locus_tag="KRN00_002279"
     CDS             11099..14128
                     /locus_tag="KRN00_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1828143.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            14205..16271
                     /locus_tag="KRN00_002280"
     CDS             14205..16271
                     /locus_tag="KRN00_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBH1828144.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     misc_binding    16655..16865
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17091..17906
                     /locus_tag="KRN00_002281"
     CDS             17091..17906
                     /locus_tag="KRN00_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBH1828145.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     gene            17934..18611
                     /locus_tag="KRN00_002282"
     CDS             17934..18611
                     /locus_tag="KRN00_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1828146.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            18670..19392
                     /locus_tag="KRN00_002283"
     CDS             18670..19392
                     /locus_tag="KRN00_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH1828147.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            20040..21191
                     /locus_tag="KRN00_002284"
     CDS             20040..21191
                     /locus_tag="KRN00_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBH1828148.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            21237..22412
                     /gene="thiI"
                     /locus_tag="KRN00_002285"
     CDS             21237..22412
                     /gene="thiI"
                     /locus_tag="KRN00_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBH1828149.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEEATILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            22568..23371
                     /locus_tag="KRN00_002286"
     CDS             22568..23371
                     /locus_tag="KRN00_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1828150.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYSPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            23614..24255
                     /locus_tag="KRN00_002287"
     CDS             23614..24255
                     /locus_tag="KRN00_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBH1828151.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYGAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         9799 a         2513 c         4395 g         7899 t
ORIGIN      
        1 gtaagtatac ttgatagtac taatacaaca gacaatatca ttattattaa tctttttttc
       61 atatttagtt ctccttttta aatttattgt gtcgacatat ttatagtata tagtaccttt
      121 aaatttacct tcaatatgtt tttaattaca aaactgttgt aaaaaatata actttattta
      181 aaactttttt ttaatatgta aatatatata ctaatagggg gtacttattt ttagaatatt
      241 cagtaaaata gttttgatat actctatata ttttgtatgt taaaagtaaa taaattattg
      301 ttaaagaagg taaagacttt taaatttctt atcataggat tttaagtaaa taagaaggat
      361 tggagtaatt aaaaattttt attttgcaaa aataagtatt tatttatatg gataaatttg
      421 attttaaatc tataaatata gataaaatct aattatttaa cttcaactat tcctcaaaaa
      481 agcaactttt aaggaatagt tgaagcaaaa agtttggtta cataatagta attttagtta
      541 caagaatgaa actgtaaaac ttaggatttt ctttatataa tttcattgag aacatttaat
      601 ttaggaggta agatatgaaa gtaaaaaaat ttaaaagtgg tatagtaatg gcattaacag
      661 taatggcaat tggagcatca ttgacaaatg tatcagctat ggaattaaac aagagtaaag
      721 agtttgaaac taaatacaat gaaatgaaga gggattttca agaggaatat ggaaaagaag
      781 acaaatttaa tataacattg gatgatgaat ttacaaaaga agaagtaaat ggagctaaag
      841 ggattataaa gacaactaat aaaatgaata atgaggttgt agtattaaat tattttgatg
      901 aaatgaaatc tggaattgaa tttgagttga agccaaaagc agaaaaaaat gcaattttga
      961 gagatgaatt tcaacaaggt tatggaaagg aagataaatt caaagttgtg ctagatgatg
     1021 aatttacaaa agaagaggta aatggagcta agggcattat aaagactaca gataaagaga
     1081 caggtgaggt tatcatatat aattactttg atgagcttga aaaataatgc ttaaagatta
     1141 ctttgattga atgaaaaggt aattgtgttg agaatataaa atgactgaat aaaaacagtt
     1201 gtatcaaaac aaacaataat agaatgtaag aatgattgtg tcgaaaatat aaaatgactg
     1261 aataaaaaac gattgtgtca aaaacaaata ataatagaat gtaagaatga ttgtatcaag
     1321 aatataaaat gactgaataa aaacgattgc gtcaaaaata aacaataata gaatgcaaga
     1381 atgattgtat caagaatata aaatgattca acaaaaaacg attgtgttaa aaacaaacaa
     1441 taatagaatg taagaatgat tgtatcaaga atataaaatg attcaacaaa aaacgattgt
     1501 gtcaaaaata aaaaataatt aagtgtaaga atgattgtat caagaatata aaatgattca
     1561 acaaaaaacg attgtgtcaa aaataaaaaa taattaagtg taagaatgat tgtatcaaga
     1621 atataaaatg attgaataaa aaacgattgc gtcaaaaata taaaataaat taaaagaaaa
     1681 agattatatt gaaggaaaaa gatttgaaat aggggtgaac tttacatatt atagttcacc
     1741 cttatacaaa aatataaaat ataatttatt ataggaaaat ttaaaaaaat cagtctattt
     1801 aatttatact gatatattgt aggattttac aaacaaactg ttatataact ttttttatct
     1861 ccaattttga ttttaagata tctaagaatt tataacaatc ttctggatat atttctccca
     1921 tatttgctac ttggaatatg ttagcatcta ggaatttgcc ttttcctgga tagacaacat
     1981 agccactttc cctttctagc cctaatataa actcatttac attgatttct ttaggtagaa
     2041 atacagatgt tactgtatta gacatatact tatctggaag taaaaatgtt agacccaatt
     2101 cttccatacc ataccttaaa atagcagaac attctttgta tctttctatt ttactgtcat
     2161 cttccaaaaa ttcagttaaa gcttcattaa gggcaaatat taaagtaaca ttaggtgtat
     2221 ttggtgtttg agaagatgat ttagcaactt tatagtgttt ataaagatta agatacacat
     2281 tcttacattg attttcttta atattttgta aaatactctc tttagcacaa aggtatgcag
     2341 aacctggaaa tgctccaaga gctttgccac caacacctgt tattatatct atattaaact
     2401 cttccacatc aatatattca cctgctgagg cacttattgc atctacaaaa aatattttgt
     2461 tatacttctt agcaagtttt cctagttcag ggactggatt tatcattcct gaactagttt
     2521 catggaacac catagcaatt acttttatat cagaattttc aattatgtat ttttctaaaa
     2581 tgtctaggtc cgggtattct gcccattcaa aattaggttt atatgttttt acattataag
     2641 tagataatat ttcttctagc ctttctccaa aaacaccatt actaactagc agaactgcat
     2701 cttctttgtc aaagatagaa gatagtacac attcatttac agatgttcca gagccagata
     2761 caattaatga gtagtaatta gaagttgcat tatatagttt attgattttt tgttgtgtat
     2821 ctttgaataa atccataaac tcatttcctc tatggcatat atcatagtga agaagtgaat
     2881 ttcttacttt atctgtaacc attactggtc caggactgaa tagatatgtt tttttcattg
     2941 taaagcctcc ttaaaaagtt aaatttaaat ttttgaatga ctgattatgt gtaaatatta
     3001 aaatgttatg tgttatttta actagattat agaataaaat aataaatatt gcaataatat
     3061 ttcaataaaa atactttttt aatcactata attaaaaata acaaaaaata ttgtaatgaa
     3121 tattgcataa atccacatga tgatataaaa tataaataac ttgaatagat tatatattca
     3181 aaaaataaaa aaaaaattat taattctgaa aataaagggg gacatttaaa gtgaaatatg
     3241 tattagcaat tgaccaagga acaacaggaa caagagcagt attgataaac gaaaaatcag
     3301 agtttgtttt tagcgattat atggaacata ctcaaatata tccacaatct ggatatgttg
     3361 aacatgaccc tatagaaatt tggaataata caaaaactgt gagtaataat gtattacaac
     3421 aggcttttga aaatggaatc aatgaaagtg atataaaagg aattggtata gataatcaag
     3481 gtgaaacagt aatgttatgg gataaaaata caggtaaacc actttacaat gctattgtgt
     3541 ggcagtgcag gagaacttat gattatgtgg aaaatttaaa gaatatacca ggtttagaaa
     3601 ataagataat agataagact gggttaatta tagacccata tttctcaggt acaaaaatta
     3661 aatgggtaat agataatgta aaaggtgtaa aagaaaaaat taaaaatgga gaagtacttg
     3721 caggaacatt agatagttgg ttaatatgga aaatgacagg aggaaaatct tttttaactg
     3781 atgtatctac agcagcaaga acaatgcttt ttaatataag agatatggat tgggatagag
     3841 agttgcttga cattatagga gtacctagaa gtattttagc agatataatg cctacgagtg
     3901 gtgattttgg aactacagat aaggaggcat tttgtggggt ttctataaaa attactgctt
     3961 caatggtaga ccaaccagca gctttatttg gcaatggatg ttttgaacca ggaatggtta
     4021 aaaatactta tggtacagga tgttttctat atatgaatat aggtgaggaa ctaaatatag
     4081 caggtaatgg tattttgaca actgttgctt ggaaaatagg agataaagtt acatatgctt
     4141 atgatggtgg agtgtatata gcaggtgctg caatacaatg gcttagagat ggcattggag
     4201 ttataaaaaa ttattcagaa actgatgaca tggcaaattc catatcaagt actggaggtg
     4261 tatattttgt accagcattt gcaggtatag cagcacctta ttgggaccaa tatgctagag
     4321 gtacaatggt tggaataaca ggaagtacta aaaaagagca tatagtaaga gcgactcttg
     4381 agtctgttgc acttcaagtc aaagatgttg ttgattctat gaacttagcc tcagggaaaa
     4441 aaataaaaat gttgagagta gatggtggaa ttactaaaaa taactttaca atgcaatttc
     4501 aatccgacat attaggtata ccaattgaaa ttgcagaaaa tcctgagacg acagtacttg
     4561 gagtaggata tatggcaggt ctttcttgtg gtgtctggaa cagtattgat gaaattagaa
     4621 gtgaatttac aataagcaaa aaatatattc caaatatgac tactcaaaaa agagaagaaa
     4681 tattacttgg atggaatcaa gcagtaaaaa gagctatgaa ttgggaaaac gataccaaaa
     4741 aggtgtgtgc taattaagtt acaatagagt attttacatg tataggagga attaaaaatg
     4801 ccctttgata aaattatatt atacataatg gctgtgggag tgcttttagg agcgttagat
     4861 agaataattg gaaataaatt tggacttggc gagcagtttg aagaagggtt taattcaatg
     4921 ggtccattgg ctttaggaat ggttggtata gtttgtttag ctccagtaat ttcagatgta
     4981 ctaggtccta taataatacc aatcttcaat ctctgtggag ctgacccatc tatgtttgca
     5041 actattttag cgaatgatat gggagggtat ccattggcta tggaacttgc acacaataaa
     5101 gaggcaggaa tgcttgcagg attggttgtg tcatccatgc ttggatgtac attagtattt
     5161 tcaattccag taggactagg tcttatagaa tatgaagaca gaccattctt tgcaaaaggg
     5221 ttactgatag gcttgataac aatacctttt ggaggtatta taggaggatt aatagcagga
     5281 tttaacttat caatggtaat tataaatatg ataccagtga taatattggc agtaatattg
     5341 gcagtaggtt taaaatttaa ttctacgctt atgataaatg ggtcattaat ttttggaaaa
     5401 tttatatcta tattgataac aataggtttg ggagcagcag catttcaaga aataacaggt
     5461 atagtactta taaaaggcat gacacctata agagaaggta ttcaagtaat tggaagtatt
     5521 gcaatcgtgt tattaggtac ttttccaata ttacatttat tagttaaagt tcttaataaa
     5581 ccacttacaa tagtgggtgg aaaattaggt atggatgcca ctagtgcagc aggattagtt
     5641 tttactttag ccaatagtat tccagtatat aaaatgatga aagatatgag tccaaagggg
     5701 aaagtagtaa atactgcttg gctggtttgt gctacagcag ctttggggga ccatttagga
     5761 tttacagcag gagtagttcc agagatgatt acacctgttg taattggaaa attggttgga
     5821 ggagtattgg caattgcact tgctatactt atgacaaaag atttaacctt ggaagaagaa
     5881 caaagtatta aaatgaagaa agatgcagtg tagaataaac aatacttaag tcaaatttaa
     5941 attattttaa agtaggagtt taaataacta aaaataaatt aaaaagacag acaattaaaa
     6001 aataatcgaa taactaaaac ttataaatta aataaaatgg caatcaaata actaaaaatg
     6061 ataagctaac tgaaagtagt tacataatta aaatataaag tatagtttag acataaatgg
     6121 agctaaataa ataattattt ggctccttaa ttttaattta ttacatcaag gaactaaaaa
     6181 tcaatcatat aagctaatta tcagctatga ctaaaggtat tcctttttga gaaaactcta
     6241 ttattatatt atggtctata ctagcagagg taataatagt atctatatgt tctataggag
     6301 ctactgatgc aaatgaattt ataccaaact taggaggttc gacaactact atagattttc
     6361 tagacctttc aatcattttt tttctaacaa gtgcttcttc taagtgatag tcagagattc
     6421 cattttcaag agtgatacct ccagcgccta aaatagcttt atcaacatta aattgttcaa
     6481 tagctgacag tgtaagcgga ccagaaaaag aaccttcagt ttctctaaga tagcccccaa
     6541 gcacatatac ttttatatta gtattcataa gttcgtttgc aactaaaatt gagttggtta
     6601 ttacagttag attcttttta tctttcaaat tttttgaaac ttcaagtaca gtagttccag
     6661 tatccataaa aatagtatca tttgtattta taaactcact acatttaata gcaatctgtt
     6721 ttttatcgtt tgagtttatt ttttttcttt taatatagtt aagttctacg ctacttgcta
     6781 taactggtat agcaccacca taaactcttt ttaaaagacc gatactctcc atatgggcta
     6841 aatctcttcg tgcagtttct attgatatat caaacatttg aactatgtca tttattttaa
     6901 ttatattatc tgatttgaga atacttaaaa tcttctcata tctttcctgt ggtaacataa
     6961 aatatcctcc ttggactagt attattttag ttttggcata acttacaatt aagtcagagt
     7021 ttaggtatat ttgttaatgt atgtatattt atcaaataat attataagtg ttatgcaaga
     7081 taattttacc atatttaaaa cttacattta agcaaaaaag taaaaataga tgtttaataa
     7141 ttcaaaataa ctcaaatttt ataaaacaat tgactaaaat atgattttat tatataattt
     7201 actagtatag agatatggag aagtactcaa gtggctcaag aggatcccct gctaagggat
     7261 taggctgggt aaccggtgcg agggttcgaa tccctccttc tccgccaatt attaaaggct
     7321 atttttatta aagatagtct ttttataatg tcataaatga ttagatatgt ataactaaag
     7381 aaaggaggga atagatgaca actttaattt ttttcatagt ggggatagca tctttggtag
     7441 ttgcttttgt tattgatggg ggacatgttg gagcattatt tgtattttca tcagcacttg
     7501 ttgtgtttgg tggaactata ggagctgttg gagcttcgac tccattccct gtgtttaaaa
     7561 agtctataaa gataatgtta ttagctttta aaaataaaaa gcctaataac atagaaaata
     7621 taatctattt caaagaaatt gcaacaaagg ctaggaaaga ggggcttctt agtattgaca
     7681 aagaaataag tgagaatgat gaattagacc cttttattag aaaagggctt gaacttatgg
     7741 tagatggagt ggatgcagtt actataagaa atatattgga atcacagata cagataacat
     7801 caaaacgaca taaagaagga atagcaattt ttgattcagc aggtggatat gcacctacac
     7861 tggggataat aggtacagtt atgggattag tacatatttt aggtaatctt tcaagtaatc
     7921 cagatgcatt aggacctcaa atttctgttg catttttggc tactttgtat ggtgttggtt
     7981 ctgccaattt aatatggtta ccaatagcat caaaacttaa ggctataaat caacaagaag
     8041 taagtgaaag acttttggtg atagaagcaa tattatccat acttgagggt gataattcta
     8101 atttaatgac agaaaaatta aaaatatttt taaattcaaa agaactaatt gaacttgaag
     8161 aaattggtgg tagagctgaa taatataaaa ggatggaatg tttatgttgt atgatgaaga
     8221 tgaaaaagaa gaaaacaatg agcgatggct tttaacttat tcagacctca taacattact
     8281 tatgattttc tttgtaataa tgtattctat gagtaatgtt gatgcggaga aatataaaca
     8341 attatctcaa tctctaaatt ctgcttttgg tggttcttct ggagttattg aaggtggtaa
     8401 tagcaagata gaaccagtag ttgaaccagg aagtaatgat ttagatactt tacaaaatgc
     8461 taagtttaaa aaaattggtg aagaaattca gaagtattta aacgaaaatg gtatggctaa
     8521 ttcagtatca ttaagagttc aagatagagg attagtaata agccttaaag atacaatact
     8581 atttgataca gggaaagcta ttgtgaagga taattctaga gataagatta ttcaaatagg
     8641 taagatgtta aatgaaatga atagttacat gagagtagaa ggccatacag acaatatgtc
     8701 tataaaaaat tcagagttta agtcaaattg ggatttatca gttatgagag caaccaatgt
     8761 tgttcaactt cttattgaca atgcaggtat agcaccagat aaattatctg ctgtaggata
     8821 tggtgagttt agaccaatag cagaaaattc atctgaagaa ggtaggtcaa aaaatagaag
     8881 agttgatata gttttagttg atagtaaata tgataatgta gaaaatgttt caaaggataa
     8941 atagttaaat tagctgtctc aatacagaat taattctaaa ggagatggct tttttatgcg
     9001 aaaatcaaaa atagatacat agtaagttac ctttttgtag gaatatatgg tatcttaaat
     9061 atataatatt taaataatgt ataagctcaa ttaaaaaatt tatagaggat ggaaaataaa
     9121 tgggaaataa aaataaaaat actaaatata aagataaaac aagagaaagg tataataaaa
     9181 aagttgagaa tttaaataaa gaaaaattaa ataaaattaa taagcaatct aagaaagtag
     9241 ataagattga tgatattatt aataaatcta gtattgtatt atgtgtactt ctagtagtgt
     9301 tttcattgct ttacttattt aaactggttc aacttaatat aataatgata cttttagtaa
     9361 ttacagtagc tattcaacaa ggattggtgt catttggtgc atttagaaat aaaaattatg
     9421 taaaagcttt attttctata tttgtaatag tatgtttctt aattgctttt aaatatgttg
     9481 taaatcctgt ttaaatatat caataaacgt tctataatta atataaatag tgaagttaca
     9541 gttttaatgc tattataaat tttataattt gaaggagtag attttatgaa taggtgtaag
     9601 tttgcaaaat taattatcac atcaatgatt gttttattac ttacaggatg tagtttaaag
     9661 aaggaagata attataagtt agacccagaa aatccgacat caatacaaat ttggcattat
     9721 tataatggac agcagaaaat ggcttttgat aagcttgtta aggaatttaa tgacactgta
     9781 ggtgctgaaa aaggaattat tgttgaagca ttcagtcaag gtaatgtagt tgatttatca
     9841 gagaaagttt tagattctgc aaataaaaaa gttggttctg aagatgtacc aaatatattt
     9901 gcagcatact cagatactgc atatgaaatg gataaattag ggttactagt agatatggat
     9961 aagtacataa gtaaagaaga attaaatgaa tacatagacg aatatgtaga agaaggcaga
    10021 ataaattcta aggatgagtt taaacttttc ccaattgcaa aatcaactga aattttgatg
    10081 ttaaataaaa ctgattggga taaatttgca aaagctacaa attcaaatat aaatgatata
    10141 aaaacaattg aaggattagt agagacatca aaaaaatatt atgaatggac agatagttta
    10201 acgaaagagc ctaatgatgg taaagcattt tttggaagag atgctttagc aaattatatt
    10261 attataggaa gtaaacaact aggagtagaa attttttctg ttaaagatgg taaagttaca
    10321 ctaaatattg atgaaaaagt tatgaaaaaa ctatgggata atttctatgt accatatata
    10381 aatggatatt ttgcttctta tggtaagttt cgttctgatg atgcaaaaac aggtgatata
    10441 ttagctcttg taggttctag ttcaggagca gcatactttc cagatagagt aatgctaaat
    10501 gataatgaga gttataatat tgaaacatct gtttttcaag caccacgttt taaaggagaa
    10561 ggaaaatatg ctgtacaaca aggtgcagga atggctgtaa caaaatctac taaagaagaa
    10621 gaatatgcat cagtagaatt tttaaaatgg tttacagata aagaacctaa tataaaattc
    10681 tctattgctt ctggatactt accagtaaag aaaaaaacga atgatttgga tgttataaaa
    10741 gaagttatga agaaagataa tttgagttta tctgataaag ttgaaggttc aatagcctca
    10801 tctattgaac agattaacag ttgtaattta tatactaata aagcatttga tggtggaact
    10861 aaagctagac aaatacttga atattcaatg cttgataaag ctaaagaaga ttcaaataaa
    10921 ataaatgaat tagtaaaaag tggaacttct aagaaggatg cagtagcaca atttaataat
    10981 gataaaaatt ttaaaacttg gtttgaaaat tttaaggctg agcttgaaaa tgctataaaa
    11041 aaatagatga attggcagtt agtgtgttga cgagcacaaa ggtataggtg gaatgggtat
    11101 ggaaaacaat ctaagaaaaa acaattcaat aatgaaaaag atgatatttc ccctaattat
    11161 tgttatgcta attcaaacaa gtttattttg tgccacaatt ttatggggag gaactattaa
    11221 gaaattaaat gataattcgt ttgacatctt aaatgaaaga gtaattaatc gtaaaaatta
    11281 tatacaaaat gaaatgttac aaagatggtc aaatacaagt gaaacggaag ctacaattaa
    11341 ttcctctgta aaaaaagtat taaatgaaaa aaatgcctta attgaggatg taggcaacaa
    11401 tgaagaaatt aacaaagata ttataaaaag catatcaaat gatttaatat atcttttgag
    11461 aaaaaattct gttacaggag cttttataat cctaagtgac aaaaatatta acgataagtc
    11521 aatagatagt aaaggtgaaa taagtaggac aggattgtat ataagggatt tagaccctaa
    11581 gtttaatcca aatgataatt ctgatttgtt aattgagaga ggttcatcag atatagcaag
    11641 aagttttgga atatctatgg acagttattg ggaacctaag ttttcattta aaagtgaaaa
    11701 tgagcaagat ggagatgatt ttttttataa accatttaga gctgcaattg ataatccaaa
    11761 tgtatcaagt tctaatttag gatactgggg aagtaagttt ttattgacaa atgcaggtga
    11821 taggcttatg acatatacag ttccccttat ttatgaagat ggaactgtat atggagtact
    11881 tggaatagat ttaagtgtaa attatttaag agaattactt ccatactcag agataaatgg
    11941 gaataaaaag ggtaattata ttttaggtgt agatagaaat aatgatatgg cctttgaaaa
    12001 tgtaatttca aatggatact cattaaaaga aaaattttgg gatggtttac attctaattt
    12061 agagcagaag gaatcgtata aaaatatata taagattaaa aataaagata atgaatgtgg
    12121 taatggcaac atttatgcta gtgtacaata cttagattta tataactcca atactccatt
    12181 tgaaaatgaa cgttgggctc ttttgggtat tattgaagaa aaaagtcttt tgtcattttc
    12241 aaaaagggta gagaaattag ttataatatc tatagcaatt tctttattaa taggtctaat
    12301 aggtatttat attgcatcaa gattatttac aaaaccaatt gttcttttag ccaacaaagt
    12361 tagaaacagt aatccatcaa aaccagtaaa tcttgataag ataaatatat ctgaaataga
    12421 tgaattatct tcagctatag agttgctcag tgcaaatgtt gcagattctt cgtcaaaatt
    12481 atcacagatt attgaaatgg tagatatgcc aattggagct tttgagttat acaaaaacgc
    12541 agagaatgtt ttttgtacaa aagaattttt tagcgtgttt actactgaaa tcaaatttga
    12601 agaatatgga tatatggaaa aaaataagtt cctgaaaaaa ttaaggggac tagataaata
    12661 tttgcaagaa agttatgaaa cagaaaatac atatatatat aagtttgaat ctaaagataa
    12721 aaaacttaag tggataagaa tgaatatctt tgaagatgag ctaaaggttc ttggtgttgt
    12781 tgttgatgta acaaaagaat ttattgagaa aaggaagata gaatatgaaa gagattttga
    12841 tattttaacg aatcttttaa ataggagagc ttttcattca cagatacaag aaaaatttaa
    12901 gaataaagat gaacttaaga tagcagcatt tattatgtgg gatttagata atctaaaata
    12961 tattaatgat acatatggac atgatgctgg tgatgaatat attaggtgtg ctgcagacat
    13021 acttaagaag tttatatcat ggaatggtat agtatctaga ctttcaggtg atgagtttta
    13081 tgtatttata tatggatatg aaagtaaaga tagtataaga gatattatta attctgttaa
    13141 gaaacagatg aataatacct tattaaaact tcatgatgga acagaattta aaataagggc
    13201 atcagcagga atttcctggt accctgatga ctcaaccaac tatgatgaat taatgagata
    13261 cgcagatttt gctatgtatc aaattaaaaa tacaatcaag ggtgaagtta gtgaatttga
    13321 tattaatata tataataagg attcattctt attgagtaat agagaagaat taaacaagtt
    13381 aattgatggt caattagttg agtatgcatt tcagcctatt gtagattgta aaggtaaagt
    13441 ttttgcatat gaagcactta tgagacctaa aataaaaact tttagttcgc caatagatgt
    13501 cattagatta gctcgttcac agtctaaatt atatcaaatt gagcgtatta catggtttaa
    13561 agcacttaaa tcatttaaaa aatacaaaga aaaatttggc gattgcaaac tgttcttaaa
    13621 ttctattcct aataataatt tgtcaaaagt agattttgag gaaattgaag atttatatgg
    13681 tgaatattta aatagagtag tactagaaat aacagagaat gataagatta atgaagattt
    13741 tattgagaaa aagaaagcat atatagacca ttggaatata gaaattgctt tagatgactt
    13801 tgggacaggt tacaacggag atgctgtact attatatata atgccagact atgtaaagat
    13861 tgatatgtct attgtaagag gtattgataa agatgaaaac agacagaaaa tattaaaaaa
    13921 tcttatctca tattctaacg aaagaaatat taaagtgata gcagaaggtg tagaaacaaa
    13981 aggtgaaatg gaaacactaa ttaatcttgg agtagattat atgcaaggct actatattag
    14041 taaaccatca tttatacctg aagatataag cgacaaaatt aaaaaagaac tcaagatatg
    14101 tcatgaaaat aggaatgatg tggtttaata gaggaaaaat taaatttatt tttatgaact
    14161 tttagtttat aattaaaaag aaaataatat aattataaat caaggtggtg gagctaataa
    14221 tcacaacaaa tatagatata agaaagttaa atgaaaatca attagaagca gttgagcata
    14281 tagatgggcc ttgcatgata cttgcagggc ctggttcagg taagaccaga gtaattacat
    14341 atagaatagc caatatggtt gtaaacaaaa acatagcacc aacaagaatc ttggcaataa
    14401 gttttaccaa ggcatcttca atagaaatga aaaatagagc tttgaattta agtgatgaca
    14461 taagacttaa taaggtaacc tatggtactt ttcactctgt attttttaaa attctaagat
    14521 actttgaaag atacaactta gacagtatat ttgatgaaaa gtcaaagcga atgacaatca
    14581 aggcaatcct aaaaagttta aatatagaga atgctgatga tgatgagaat ataggacaag
    14641 ttataaatga aatttcctat gtaaaaaatg aacttatgga taaaaatgaa tttaattcag
    14701 aagtattaac aaaagatgag tttttaaaag tatacaactt atacgaagaa caaaaatcta
    14761 aagttaataa aatagatttt gatgatatgc ttataagaac ttattattta cttttgaaca
    14821 ataagtctgc actagaaatg gttagaaatg tgtataaata tatattgata gatgaatttc
    14881 aagatataaa taaagtacag tttgaagttt taaagttaat ttgtagccca ttaaacaata
    14941 tatttgcagt tggagatgaa gaccaaagta tatatggatt tagaggtgct agaccagatt
    15001 ttttgcttga atttgaacaa tactttaata atactaaaaa aataatatta gatataaatt
    15061 acaggtctaa aagtgagata gttcatactg caaatagact tatcgacaaa aataaaaata
    15121 gatatgaaaa aatcattaag tgtagtcagg gggatggagg aagtgttacc tatatttctc
    15181 cgcatgattc agaggaagaa gccttatata ttgccaggga aataattgac gaaatacaaa
    15241 aagattatgt agagtattca gattttgcag taatttatag aactaatata cagtcaagag
    15301 cattagtaga tgtatttatg gatatgagga ttccatttgt agtaaaagac tcagtaatta
    15361 caatatatga ccattgggca agtcaagaca tactagccta tttaagaata ggtattaatc
    15421 caaaatcaaa taaagattgg ttgagaatta taaacaagcc ttttagatat atatccaaag
    15481 acagtataaa tatggttaag gatgaaaaag actttataac agcattaata aataagtgta
    15541 atcttcatcc taaacaagtt aaaacaataa atgatttgga aatagattta agttatttaa
    15601 atactttaaa tcctaaaaat gcaatatctt atattagaac tagtcttgat tatgatagat
    15661 atgttttaga ttattgtagc aacagaaaga taaagactaa tggacttgta gagatattaa
    15721 atgaacttga gagttcagca actaatttta atactgttac agagttttta gagcatattg
    15781 atagagtaaa gactgagtta acggaaaata acaagaataa gcagactgag ggtgtcatat
    15841 ttacaactat gcatagtgca aaaggattag aatttagaaa tgtttatatt ataggtgtaa
    15901 atgaaggaac aatacctcat gaaaaatcat atgatatttg taaggaagag aaaaaagaag
    15961 aacaattaga agaagaaaga agacttatgt atgttgctat tacaagagct gaagaaaagt
    16021 tatgtataag ctctacttta aataagtatg gtaagaaagt tgataaatca ttatttatta
    16081 atgatataaa atctccaacg aaaaaagaaa ttgacagtat tggtgtaggg gataaggtat
    16141 accataaaaa atttcatgaa ggagaaataa ttaaaaaaga tggaattatg tttacaataa
    16201 agtttaaaga tagagagcga atcttggatt tgaaaacttg tttattgaag aatataattt
    16261 atactattta atttagaatc taaatttaga tagaaatata atgtattatt tattatgtgc
    16321 aagacaaata gatatgtgta aaatgtatta tttaacttat tagaaaaaag aaataagggt
    16381 ttaatatatt atttatagtt gtttagaaaa agcaacaatg tggaaaatat tatttagtat
    16441 tattaaagaa aagcaacaat gtgaaagata ttatttagta ttatttaaga aatagctaaa
    16501 aatatgaaat atactattta taattacaaa actaatatca ataaatataa acagtagtat
    16561 ttagataatt tacaagtaaa aattattaaa aaaataaaaa acttattgac aaaaatatta
    16621 taaggaagta caattgtatt aacaatttaa ggaaacaaat ccaatgatag agaaagtagc
    16681 atatatggat ttacagcgag ttaggggttg gtgtaagcct aacaatgaag tctatgtgaa
    16741 gagagctctg gaggagatta tcagaaactt tagtatgata attggtttac ccgccttaag
    16801 ggattgagag gataagtact tacttatcaa aaagagtggt aacgcggata taattcgtct
    16861 cttagctgta aagctaaggg acttttttga ttttaaaata aaaatatcca tacagcttaa
    16921 aagctaacag tcacaaattt tgaaagtaat ataagtattt atcaataaga gtggtaacgc
    16981 ggtaaagtcg tctcttagtc attaaagact gagagacttt ttttgtaact cgaaacattt
    17041 aagtattaaa atctgaggga aattataatt aaaagagagg ggtagttaaa atgaaagtat
    17101 ttaaaaaatt attaagttta ggattagtat taggattgac attatcgcta gtaggatgta
    17161 gtggtggagg agaaaaaaca aagttagaac aaataaaaga caatggaaaa ttagttgttg
    17221 gtactagtgc agaatttcct ccatttgaat ttcataaggt agtagatgga aaagattcaa
    17281 taaaaggatt cgatataatg ttggctgaag aatttgcaaa agagcttggt gtaaaggttg
    17341 aaattaagga tatgtcattt gatggattaa taggtgcttt aaatgcagac caagttgata
    17401 ttgttcttgc aggcatgtct ccaacaccag agagagaaaa gagtgttgat ttttcagaat
    17461 tatattattt aagtagaaat gcagttatag ttaaagatgc agatatagac aaagtaaaaa
    17521 ctgaagatga tttaaagaaa cttagagttg gagttcaagc aggaagtatc caagaagaat
    17581 atgtagttaa cactttaaaa atgacaacta caaaatcttt gaaagcaata cctgatttaa
    17641 ttacagaatt aaaaaatgga aacatagatg cagttgttac taatgaagca gtttctttaa
    17701 taaatgttaa aaaatatgat ggaataaaaa tggcaaatac tgaagttggg aaagatgtaa
    17761 cagaaggtat ggcagcagca atcaaaaaat ctgacaataa caaagatttt atagaattat
    17821 taaacaaaaa gataaaagaa ttacaagatg gcaagaagat agaagaattt ttaaatgaag
    17881 catctactga agctgcttca aattagtaag aaagttatgt gggagatgaa attatgagtt
    17941 tagattttag ttttttaagt agatttggga cttctttttt ggaaggaaca ggtgtgacag
    18001 tatcaatttc tcttgtggca ttatgctttg gatttataat aggtataatt atctgtatgg
    18061 caaaaatatc aaagagcaaa gtattaagag caatatcatc aatctatatt gaggttttaa
    18121 gagggacacc attattagta cagatatata tagtatggtt tggtttacct caattaggaa
    18181 taagattccc tatgttgttt ggtataccaa gtgaatttat agctagtgca tttgcattat
    18241 cagtaaactc tggtgcatac gtggcagaga tacttagatc aggtatacaa tcagttgata
    18301 atggacaaat ggaagcaagt agatcattag gattaaatta ttggtcaact atgagatata
    18361 taataatacc tcaagctata aaaaatatat taccttcatt agcaaatgag tttattacac
    18421 ttgtaaaaga atcttcaata atatctgtaa taggagttgt tgagataatg cgtactgctg
    18481 atatagtaaa aaatgcagca tttagagcat tagagccatt aatagtagca gcagcaattt
    18541 actttgttat aacatttact ctatcaagat tagttggatt attagaaaag aaactatctg
    18601 tgtctaacta gatgagagca tgtttagcat ttagggaaaa catagaatag taaaaaggaa
    18661 agtgataata tgattacaat aaaaaattta agtaaatctt ttggagattt aaatgtatta
    18721 aaaaatatag acttagaaat cgctaaaggc gaaataatgg ttatagtagg tccaagtggt
    18781 tctggtaaaa gtacacttct tagatgtatg aatttactag aaatacctac aggtggagaa
    18841 ataatatttg aaggaaaaaa tttggtcgat aaaaaaacta atattgatga ggttagacaa
    18901 aatataggta tggtgtttca gaactttaat ttattcccac ataagactat tttagataat
    18961 ataacattag caccaattaa attaaaaaag atgactaagg aagaagcaga aaaaaaagca
    19021 gaaattttgt tgagtagagt tggtctttta gataaaaaag attcatatcc atcacaatta
    19081 tctggaggac aaaagcaaag aatagcaata gctagagcac ttgctatgga accagatatg
    19141 atgttgtttg atgagccaac atctgctctt gacccagaaa tggtaaacga agttttggat
    19201 gttataaaag aacttgctaa agaaggtatg acaatggcaa ttgtaactca tgagatggga
    19261 tttgctaagg aagttgcaga tagagttatt tttatagatg gaggaagtat acttgaagat
    19321 aatactccag aagaagtttt cggaaatcca aaacatgaaa gaacaaaagc atttttagca
    19381 aaagtgctat aatatataaa aaggatgtta ttgatattag aaattcaata catccttttt
    19441 tagtgatggt taatattaat tttaaaatta aagttatatt aatattaact ttatttttac
    19501 gattttttgc agaaaaaaaa agagctcggg gtaagctctt tttttccacc gaattaattt
    19561 ccgttactaa tccgattttt aataaatata aaatatatcc ttatgaaagg gtattgggaa
    19621 tagatatatt aactaactag ggttaccagg gggataacct taatttatta taacaaaatg
    19681 cgacacaaaa atcaatattt tttttgaaat aaattataaa agttattttt ataacaagta
    19741 agcttataaa tttaactttt atagtaaaaa taagtatatg tataatataa tatatttatt
    19801 ttatataata tattatttta tcatatattg tattttataa tatatttttg tagggtatag
    19861 tataagtata ttatatttta ctataaaaat ttgtaataaa gtgaaaaaac tagcttttca
    19921 tgaaataata ttttataatt taagattgtc tttttaataa agattaacaa aaaaaatact
    19981 ataattagtg gtataatagt tagagttgaa gattttaaat aaaggtaggt gtaattaagt
    20041 tggaaatata cttagacaat agcgcaacta caaaacctta tcaagaagtt atagataaaa
    20101 tggtttatgc acttaatacg gaatatggaa atccttcttc tgtccataga aaaggtgtag
    20161 aagttgaaaa agctataaaa gaagtaagac aagatatagc taaatctcta ggagcgaaag
    20221 aaaaggagat ttattttaca tcaggtggta cagagtgtaa taatactata ataagaggta
    20281 ttactagttt aaataaaaaa agaaaaaatc acataatatc tactaacata gaacatcctt
    20341 ctgttttaaa tacattaaaa gatttagaag aagatggttt tgaagtaact tatttagagg
    20401 tcggaaaaga tgggaaaata aatatagagg atttaaaaaa tgcgataaag tcaactacat
    20461 gcttagtaag catgatgcat gttaacaatg aaataggaac tatacagcca ataggtgaag
    20521 ttggaaagta tttgaagggt ttaaaagaaa aaatttattt ccatgttgat gctattcagt
    20581 catatggaaa aattaacttt agaccatcta aatacaatat agattttatg agtgtaagtg
    20641 cacataaatt tcatggtcca aagggaattg gatttatgta tataaaagaa aataatcgcc
    20701 ttaagcctat gttaacaggt ggtggtcagg aaattggaat taggtcggga acagaaaatg
    20761 tacctggaat atatggtctt ggagaagctg ttagaatact aaacaaagat ttagatgctg
    20821 ttatttcgaa agtagataac ttaaaaaata tattaaaaaa tgaaataatt gataatatag
    20881 aagatataaa aatcaattct ccagaagatg gagtatgtca tatattaaat gtatcattta
    20941 gagggacaaa aggagaagtt ttacttcatt acttagagca aaaaggtatt tatgtatcaa
    21001 ctggctctgc atgttcttct aaaaagaaag gtagttacgt attaaatgct ataggtctta
    21061 caaatgaaga aataaatgga acaataagat ttagtttatc tgatatgaat acagaagaag
    21121 aaatgttaga agctgtgaaa gttttgaaag aatcaatttg tgacttaagg tcaataatga
    21181 aaagaaaata aagaatactg tataaatagt gataataaat tagtttaaga ggtgaaatgg
    21241 tgtataatat attaatagta aagtatggag aaattggagt aaaaggaaag aatagatata
    21301 tatttgagaa taggcttata agaaatataa gaaatatgtt aaaaccaatt ggaagattta
    21361 atgtatataa agagtatgga agaatatatg ttgatttaga agactatgat tatgaagaag
    21421 taattgaaga agttagaaaa gtatttggga tagtgggtgt gtgccctgga gtaagagcta
    21481 aaaaagatta tgatacatta aaagaaatag ctttaaaaat gttagaagaa aaaatagagg
    21541 ctggatataa aacttttaag gtagagtcaa gaagaggaga taagtctttc ggattgactt
    21601 ctcaagaaat gagtatggat ataggtggat acttattatc aaaggtagga gataggatta
    21661 atgttgatgt aagaaatcca gaagttaaaa taaagtgcga atacagagaa tttcatacta
    21721 tggtctatag tgatactata cctggatatg gtggattgcc acttggaacg aatggtagag
    21781 ctatgtctct tttatcagga ggtatagata gcccagtagc tacatggatg gttgcaaaaa
    21841 gaggtatgga agtagaggca gttcactttc atagttatcc atttacaagt gaaaggtcac
    21901 aggaaaaagt taaagattta gctaaaatac tggcaaaata ctgtggtaga gtaagacttc
    21961 ataaagttaa catattagaa atacaaaaag caattggtga gaattgtaat gaagaagaag
    22021 ctactattct ttcaagaaga tttatgatga ggatagcaca gagactttct gaaaaaagac
    22081 attgtgatgc tttaattaca ggtgaaagta ttgggcaggt tgcatctcaa actatacaag
    22141 ggcttacttg tactaatgcc gttgtagact taccagtgtt tagaccactt atagcaatgg
    22201 ataaatcaga tatagttgat atagccaaaa aaatagggac ttttgaaaca tctatagtgc
    22261 ctgaagaaga ttgttgtagt gtattttctc ctagaaagcc cgtcactaaa cctagattag
    22321 agaaaataga aaaatctgaa acagcacttg acattgaaaa attagtacag gatgctattg
    22381 acaaaataga ggtagaggat attgagtttt agcatacgag ttatttaatt actaaattga
    22441 atattgagta tattagtagt tctgtaagta tattagtagt tctgttgaaa ggatttatgt
    22501 agacaattta ttaatatgta gtatttaaaa ataagtacta taattttatt taatgggaat
    22561 gattattatg aataaaaagg gttttacatt aattgaattg ttggtagtta tatctataat
    22621 aggaatttta gttatagtag ctgttccagc gttatttaga aatatagaaa aaagtaaagc
    22681 agttacatgt ctttctaata gagaaaatat aaagactcaa attgttattg caatggctga
    22741 ggaatcaagt aaagacaaga atgaagtcat aaaagaggta ttagaaaaca aagatggtaa
    22801 gtactttgaa acagaaccaa agtgtaagtc aggtggaata tattcagcaa cgtttgatga
    22861 tggttatgat ggaataactg gaatagaaag cattgcaaaa gtgtatgtta cttgtacaaa
    22921 acatccagac ggtgttgaaa tggctaggga tgtgcatcaa agtatgaaag atttgattgc
    22981 atcatttgca caagaccctt ctataatacc aggagcttca aagggtaatg atgattttag
    23041 aaaatattta ttagacaata aatataaaaa tgggtggcct acaattccag atgaatttaa
    23101 ggcaaaatat ggattaagta aggatacact atatatacaa ccatatgcat atagtcctac
    23161 taaatctgat gctactgtag ttgtatttgc aaataataag actgggggta attggtatac
    23221 ttccctagtt tacgattatg atgaaggtag atggtataaa ggtaaaaatg gtatttctgt
    23281 tgcaggtagg tcatgggatg ttgacacaga tagtgttaag tctgtaaaaa cagagattca
    23341 ttctaaagag ggatggggtc ctttaaatta atatatcatg ttttattaat ctggtattga
    23401 ttaaactata gaaaagagca gtttctatag atgacgaata ccagattttc atttatatat
    23461 ataattgaga tatattaaaa gtgtttatat ttttaagcct tcacatacaa gctaaaaata
    23521 attataataa tattgtaaag aaatttaatt ataagattaa ttttctgaag atttagtatt
    23581 tgtactaaga aatacataaa aaggggaata gatatgaata ataattttca agacaaccaa
    23641 acaataaatt taatacaaag tcgtagaagt atacgaaaat ttacgacaga acaaattagt
    23701 gatgagcaag taaacacatt attacactgt gcatttgcag caccttcagg atgtaataaa
    23761 cagccttggc acataactgt tgtgcaagac cagaaacttt taaaagagat tagtgatgat
    23821 actttatcta ggattcatga ggtgagtaat gttgagataa ataaaaactt taagttattt
    23881 tatggtgctc caaccgtttt atttatttct tatgatgaaa gtagttcatg ggctccatat
    23941 gatataggaa tacttacagg gaatataaca acagctgcac aagcactagg gcttggaagt
    24001 tgtataatag gaatggttag aggtttattt acacctgttg aacaagggga tattgaaggt
    24061 cttgtgagtg tattggataa agaagatgta aaagaatcag agtcaataaa gatgaagttt
    24121 gatacaaata aaaaatacag agaactactt gatataccag aagggtattc tgtaccattt
    24181 ggtattgctg taggtattcc agatggaaat ttaccaaatg ctagagaggt agtttacaaa
    24241 gtttccagag tttaggataa agtattgcaa gaaccaatca gttacttgaa gaattaaatc
    24301 agtaatatac aaataaattg atggaagagg aagctattta aaaagtagtt tagatttttc
    24361 gttgtaaaat aattaaataa agaataaggt gataagtatt ttatttatta tcttattctt
    24421 ttttattttt gttttgtaga atgataaaaa taaggattaa gtgtaataaa atagaaaaca
    24481 agtatgttaa ttttaagtat atgctttaaa atttatccaa gttaaaaatt taagatatct
    24541 tttcagtata atggaaaaaa tgtcaaaata ttgaaatagg gaaaaaatag tgatataata
    24601 agaaaa
//
LOCUS       DAEQAF010000054        24343 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.056, whole genome shotgun sequence.
ACCESSION   DAEQAF010000054 DAEQAF010000000
VERSION     DAEQAF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.056"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            109..300
                     /locus_tag="KRN00_002288"
     CDS             109..300
                     /locus_tag="KRN00_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBH1828152.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            455..1864
                     /locus_tag="KRN00_002289"
     CDS             455..1864
                     /locus_tag="KRN00_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1828153.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVEDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQIIDLEDI"
     gene            1995..2684
                     /locus_tag="KRN00_002290"
     CDS             1995..2684
                     /locus_tag="KRN00_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBH1828154.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2687..3622
                     /locus_tag="KRN00_002291"
     CDS             2687..3622
                     /locus_tag="KRN00_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBH1828155.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3619..4512
                     /locus_tag="KRN00_002292"
     CDS             3619..4512
                     /locus_tag="KRN00_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBH1828156.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4590..5336
                     /locus_tag="KRN00_002293"
     CDS             4590..5336
                     /locus_tag="KRN00_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBH1828157.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLVQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5337..6170
                     /gene="rsmI"
                     /locus_tag="KRN00_002294"
     CDS             5337..6170
                     /gene="rsmI"
                     /locus_tag="KRN00_002294"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBH1828158.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6193..6897
                     /locus_tag="KRN00_002295"
     CDS             6193..6897
                     /locus_tag="KRN00_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBH1828159.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDKDFFPIHLRKHVSNYLNTYIEEGINKLHVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGINLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7085..7513)
                     /locus_tag="KRN00_002296"
     CDS             complement(7085..7513)
                     /locus_tag="KRN00_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBH1828160.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7550..8980)
                     /locus_tag="KRN00_002297"
     CDS             complement(7550..8980)
                     /locus_tag="KRN00_002297"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBH1828161.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9112..9696
                     /locus_tag="KRN00_002298"
     CDS             9112..9696
                     /locus_tag="KRN00_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein A"
                     /protein_id="HBH1828162.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMRRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9712..10233
                     /locus_tag="KRN00_002299"
     CDS             9712..10233
                     /locus_tag="KRN00_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HBH1828163.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10299..10545
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10629..12566
                     /gene="metG"
                     /locus_tag="KRN00_002300"
     CDS             10629..12566
                     /gene="metG"
                     /locus_tag="KRN00_002300"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBH1828164.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKGELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12596..13366
                     /locus_tag="KRN00_002301"
     CDS             12596..13366
                     /locus_tag="KRN00_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBH1828165.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGICYEEVCRVTKENAKKFFNIK"
     gene            13703..14134
                     /gene="phnG"
                     /locus_tag="KRN00_002302"
     CDS             13703..14134
                     /gene="phnG"
                     /locus_tag="KRN00_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBH1828166.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14149..14724
                     /gene="phnH"
                     /locus_tag="KRN00_002303"
     CDS             14149..14724
                     /gene="phnH"
                     /locus_tag="KRN00_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBH1828167.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14727..15812
                     /locus_tag="KRN00_002304"
     CDS             14727..15812
                     /locus_tag="KRN00_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBH1828168.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFINELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            15832..16701
                     /locus_tag="KRN00_002305"
     CDS             15832..16701
                     /locus_tag="KRN00_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBH1828169.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16694..17560
                     /locus_tag="KRN00_002306"
     CDS             16694..17560
                     /locus_tag="KRN00_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1828170.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17601..18314
                     /locus_tag="KRN00_002307"
     CDS             17601..18314
                     /locus_tag="KRN00_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1828171.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18315..19484
                     /locus_tag="KRN00_002308"
     CDS             18315..19484
                     /locus_tag="KRN00_002308"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBH1828172.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19488..20324
                     /locus_tag="KRN00_002309"
     CDS             19488..20324
                     /locus_tag="KRN00_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBH1828173.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20325..21320
                     /locus_tag="KRN00_002310"
     CDS             20325..21320
                     /locus_tag="KRN00_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1828174.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21338..23026
                     /locus_tag="KRN00_002311"
     CDS             21338..23026
                     /locus_tag="KRN00_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBH1828175.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23038..24105
                     /locus_tag="KRN00_002312"
     CDS             23038..24105
                     /locus_tag="KRN00_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1828176.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
BASE COUNT         9712 a         2716 c         4347 g         7568 t
ORIGIN      
        1 ttttttgtca aaaaaaacaa aaaatacgta tttctttttt catttcggga aaactaaaca
       61 caggaattat ggactttata aaaatttaat tcttgaggag tgatataagt gaaaaaagtt
      121 gctttaattt tagctataat aggtgcgctt aactggggtg caattggtat tctaggtaca
      181 gacttaatag gtagtatctt tggtggaaca tatgaaatgg taagtagaat aatatacttc
      241 attgtaggtt tagctggatt atacttaata ccaagtttaa tgtctgatga tagagaataa
      301 tttatgcttt tatgttaaat acctcattct aaatgtttag aatgaggtat ttaattttat
      361 aaaaatatta atttgtttct tttttaatgg taaaatagat aagaattgaa gttttaaaaa
      421 gaagtattat gtaaaaaagg agtactatta atatatgttt attattaatg aattaaataa
      481 gattgtaaat gaagaagtaa tatcttttca tatgcctggt cataaaaagg gacaggttta
      541 taaaaagtta ggatataaag atatactaaa aaatttgtat aaaatggata caactgagat
      601 attaggaaca gataatttac actttccgga aggaattata aaaaattcac aaaaaaaagc
      661 atcaagagta tttaaaagtg attatacttg ctatttagta aatggtagta gctgtggaat
      721 acaatctgca ataatgtcag tatgtagtcc taaaagtaaa ataataacaa atagagactg
      781 tcatcagtct gttataaatg gatgtatttt aggagatata gatatagagt atgtgccttg
      841 tgagataagt gaagagacaa atatcttaaa agggatatct ataagtaatg tgattgatat
      901 aatagataaa aacttggatg caaaagcagt actgcttact tatcctacat attatggaat
      961 gacatatgat ttagaataca tatgtaatta tgcacatagc aaaaagatgg tagtgatagt
     1021 agatgaagca catggtgcgc atttagggct tagcgagagg cttcctaaaa cagctcttga
     1081 gcaaggcgca gatatagttg tacagagtac acataaaact cttccagcat ttacacaatc
     1141 gtcaatgata catatacagg gagaccgagt tgatatagat aaaatattga acatgttaag
     1201 aattacagaa tcttcaagcc cttcatattt attattatct tctctggaat tagcagtaga
     1261 tatatatgaa aataaaggaa aagaattaat ggaagagctt ttaaataata ttataacttt
     1321 caaaaataaa gttgattcaa atattaatat atacgacaca aatgataaaa caaaaatatt
     1381 tatatcatct aaaaacatgg gtttaacagg ttatgaacta gaaaatattt tgagaaataa
     1441 atataacata caagtggagt tatctaatta ttatggagtt cttttaatat gtacaatagg
     1501 aaatactgtt gaggatttct ctagtttaga aacagcatta aacaatattg taaaggaaga
     1561 ctttaaattt gaaaagttag aaaataaaaa ataccctgtt gttattccaa agaaaatatt
     1621 aacacctaga gaagcatttt ataaaactaa aaaaagtgtt aaaatatatg acagcatagg
     1681 taaagtttgt ggtgaatgta tagttccata cccacctgga ataagtgtaa tatctcctgg
     1741 tgaagtaata agtaaagaaa taatagacta tctaatgttt tgtcattcta aaggcatgat
     1801 tgtgagtgga ttgaaagatg tagatttaaa ttttatacaa ataatagatt tagaagacat
     1861 ttaaaaatta tgatataaaa gtagatagaa gtagatagtt taaaattgtg aagagaaata
     1921 aatagactgc ttatatagag ctatctaata aaagtactaa aaaagtaaaa agtgtttgta
     1981 tggaggatat gaaaatgaaa ggtaagttaa taattataga gagtggttca gatgcaagtg
     2041 gaaaggctac tcagacagaa atattatatg aaagattaaa aaaagaaggc tatatgatta
     2101 aaaaggtaga atatccaaat tatgaatctc catcatctgc cttggtgaaa atgtacctaa
     2161 aaggagactt tggtaaaaat gcatcagatg tagacccata tatagcatca acttttttta
     2221 cagctgatag gtatgcatca tttaaaaccg attgggagga gttttacaat gaaggtggaa
     2281 taattatcgc agatagatat acaacctcta atatggtaca tcaggcctct aaaatggata
     2341 tttgtgatag agaagagtat ttaaattggt tagctgatta tgaatttaat ttatttaaga
     2401 taccacaacc tgattgtgtt atatttttag atgtgcctat tgaatttagt aaaaagctta
     2461 tggagaatag aaaaaataaa attacagggg aagaaaaaaa ggatattcat gaaagtgaca
     2521 tagagtattt agagaaatct tacaacaatg ctttatatat agcagataaa tatgattgga
     2581 aaaaaataaa ttgtgtttta gataacaaat taagaagtat tgaaagtata cataatgaaa
     2641 tttataaaat agttcttgat tcaataaaac ctatggagag ataaatatgt attttgaaaa
     2701 tattataggg caagattttg caaagaaata tttaacaaat tctataaaga aaaataaact
     2761 taataatgcg tatatgtttg aaggaatgga tggaatagga aaaaagaaat ttgcagatga
     2821 attatcaaaa ctattacttg attatgaaaa tctcgaaaat agtccagact atgtactcat
     2881 aaaaccagat ggaaatagta taaaaatagc tcaaatcaga aatttacaat cagatatagt
     2941 aataagacct cataaagact ataaaatata tataatcaat aatgctgaaa aaatgactgt
     3001 ggaagctcaa aatgcacttt taaagacgct agaggaacct ccaaactatg ctataataat
     3061 cttagtcaca aacaacaagg aatctttatt agaaactata aaatctagat gtgatataat
     3121 aaagttctca cctataccaa ttgaagactt aaaacgttat ttgataaata caggtataga
     3181 agaagaaaga gctcaattat tggctatttt ttcgagagga agtattgaga atgctctaaa
     3241 tctatctcag tcttctgagt tttcaatgat gagagaagat atacaacagt atattcagat
     3301 aatgttagat aaaaacatag tggagatttt aaatatacca aataatatgg aaaaatatag
     3361 aggtaagatt atagctttat tagatatgat gataaactat tttcgagata tcatcctatt
     3421 aaaagaaaat gtaaacaaga acatgttaat aaatgtagat aagctagttt tcattcaaaa
     3481 tatgagtgga aaaattagtt attctcaatt gtccaagatt attgatataa tagaagatgc
     3541 aaagagtaaa ataaaaagca attgcaattt caatataagc atacaagtta tgtctttaaa
     3601 tatatacgag gtgattaaat gataaagata gtaggtataa ggtttaaaag tgctgggaaa
     3661 atatattatt ttgaccctgt tgattttaat atagagcaag atatggatgt agttgtagaa
     3721 actgcaagag gcttggagta tgggaaagta gtcgttggtc caaaagatat ggatgaaagc
     3781 gaattagttt ctcctttgaa gccaattata agaatagcta cagaagaaga taaaaaagta
     3841 tatctagaaa ataaggaaaa ggcaaaagaa acttttgagt tgtgccaaca aaaaataaaa
     3901 gaacatgagt taacaatgtt tttaatagat tgtgagtata catttgatag gaataagttg
     3961 attttttact ttacagcaga aggaagaata gattttagag aattggtaaa agacttagct
     4021 gctatattta aaactagaat agaacttaga caaataggtg tcagagatga agctaaatct
     4081 ataggaggtc tagggccttg tggtagaaaa ctttgttgtt catcttggtt aggtgatttt
     4141 caaccagttt caataaaaat ggcaaaagac caaagtctat ctctaaatcc aacaaaaata
     4201 tctggaatat gtgggagatt attctgttgc ttaaaatatg agcatgatgt atatagtgaa
     4261 gcaatagaaa aaatgcctgt tgtaggtgca ttggtgcaat cagatgatgg aaaaggaaaa
     4321 gttgtagaag tgaatccttt attagaacaa attaaagtgg aatttcaaga caagacagta
     4381 aagatataca caagagaaga tataaaaata cttagagagc ctaaaaaatg tgatggctgt
     4441 ggtggtaaat gtaaggataa tgatggatta gatgaagcca cactaagaga gctaaagaaa
     4501 ttagaagatt aaatttaagg tagggctttt cctacctttt ttaaagcaat taatgcttaa
     4561 agttattaat atttgaggag aatttatata tgcaattaaa agattcagaa agaatagatg
     4621 atttacaatt aaaaggcctt aaaattatac aagatactaa tggtttttgt tttggtatag
     4681 atgcagtttt attagccaat tttactaaaa taaaaaaaga tgccaaagta gtagatttgg
     4741 gtactggaac tggcattata cctattttga tagctggaaa aagtgaagct aaaaaaatta
     4801 ttggcgtgga aatacaagaa gatgtatatg aaatggcaac tcgttctata aaattaaatg
     4861 gattagaaga aagagttgag attataaatg aagatataaa atacatagac aaagtcttag
     4921 acataaatgg ttaccatgta gtcacatcaa atcctccata tatgcatatt gatggaataa
     4981 aaaatccaaa tgataaaaaa gcaatatcaa gacatgaagt aaggtgcaat ttggaagatg
     5041 taattagagc tgcatccaga ttggttatgc ctagaggaaa attcttcatg atacatagac
     5101 caacaagatt ggttgatata ataactttag ggagaaaata taaattagaa ccaaaggtta
     5161 ttcaatttgt gcatccaaga cctcaaaaag caccgaactt agttttggtt caatttgtaa
     5221 aagatggaag gccagagctt aaaatattgg acccattgta tgtttatgga gaagatggga
     5281 attatacaaa agaattaaaa gcaatatata ataataaaga tataggagag ttgtaaatga
     5341 gcgggaaatt gtacatatgt ccaacaccaa taggaaacct agaagatata acatatagaa
     5401 ctttaagaat attaaaagaa gtagacttga ttgcagcaga agatacaaga catagtataa
     5461 aacttttaaa tcattttgaa atctcaaaac cactaactag ttatcatgaa cataataagg
     5521 attcaaaggg agattatttg ataaataaac taattgatgg tgaaaatata gctctgataa
     5581 gtgatgcagg tatgcctggt atatctgacc caggagaaga gataataaaa caagctatac
     5641 aaaataacat agagatagaa gtattgccag gtgcaacagc ctttgtaacg gctttagttg
     5701 gctctggtat ggacacacat agatttgttt ttgagggctt tttagataga gataaaaaag
     5761 ttaggaaagc acaattggaa gaattaaagg aagaaagtag aactataatt ttctatgaat
     5821 caccacatag attgaaggat acactaaaag atatgcttaa aattcttggt aataggaata
     5881 tttctataaa tagagaactt acaaaaaaat atcaagaaat aataagagaa aatatagaaa
     5941 ctaccataaa aatatttgag gaaaaagaag taagaggaga gtttgtatta atagtagagg
     6001 gttttcatgg tgagaagtca aagaaagaaa attatgatgg gcttacagat agggaatatg
     6061 ttttaaaact aattgaaagt ggtatgaaca aaaaagatgc aataaaaata gtttgtaaag
     6121 atagaaagtt aaagaaagat gtggtttata aacaagtttt agatttataa aacctgaatc
     6181 tgaggtgatt ttatggaaat agggaaaatt ataatagaga gtttaaagag ggaagataca
     6241 cataaaatat ttatagaatt agataataag catgaattag aaaaaataat tcctaaaata
     6301 agctgtatga agtctgtagg tgaatgtaaa tatcatgtag taaattgttt tgaacattct
     6361 ataaatgcat taaaagaatt agaaatagta ttaaatgata aggatttttt tccaatacat
     6421 ctaagaaaac atgtgtcaaa ctatttaaac acatatattg aagaaggaat aaataagtta
     6481 catgtattaa agctgggaac atttttacat gatataggta agcctgacag tatgacctta
     6541 gatgaaaccg gaagagttca tttcacaaat catgaaaaaa taggtgctca aataattgac
     6601 aatatgggaa taaatttaga gttatcaaca gagacatata gacttataag taaatatgta
     6661 agatatcata tgatactttt gtctctatat aagaaaaatg atttgagtag gaaagaatta
     6721 attaatgtat ttaacttagt agatgaggac actataggtg taataatgct tgggtatgca
     6781 gatatagtgt ctacagtaaa attattgggc aagagtggag aagtcagtgt gttaaagaca
     6841 tatatggaat atattttaac aaattacttg tataagagta attatacaca tgtataaatt
     6901 tagttaatat aattgagttt tagatgatta attaaagttt gaaatatacg gatttcaaaa
     6961 acataaaaga agttgtcttt gttgtaaaat tatgaaagac aacttttttt atatcaaaaa
     7021 ttgaaatttt attaaggata cttaatggtc tattaattaa taaaccatta gtatttaatt
     7081 tatattacaa tattgatttt gcttgtattg gcgttgatag tataacagag gtcttagtag
     7141 aaccaatttt ctttatagta tcaatcacat tttctagctc gtacatatct tttacaatta
     7201 cttttaaaag taagcaatca tcacctgtta tatggtgaca ttctacaatc ctagggtcct
     7261 ttgcagctga ctcaataaat tctgtatatc cattgcttgg aagagaaata tgaataaatg
     7321 cctttataac tctgcctaat gaatctgggt tgacaatagc tttatatcct tctataacac
     7381 cagactcttc taatcttttg actctttctg aaactgcagg agaagttaaa ccaactattt
     7441 ttcctaagtc cttcatagaa attctcccat catcctgtaa aatttctatg attctgtaat
     7501 ctgtaacatc cataaataaa cagtccccct taaataaaaa taattaatgc tataaaactt
     7561 ttttagaatc tatcatttgt gtttttaaat accaaagatt tctagataaa tcaaccttat
     7621 aaatgtgtgg ttttgaaagt cttttgtatt gttcccagat agtacttaat tcatattgta
     7681 catgattttt tatttcaaga acagcttttt tattatattt gcatctgcct tttatataca
     7741 atggtttaag aagctcttta actttgtaat ttgtaaatac cttcgttttc catgtataag
     7801 taggatggaa gatttctaaa ggtttagact catctataac ttcatcatgt aacataatca
     7861 aatctgcctc tgccttattg tcttcgttat atattcttat aactttcttg taaccaggat
     7921 tatttatttt ttctggattc tcagaaatct ttatcttagg ttcaagaact cctttttcac
     7981 aagatgcagc taatttataa actcctccaa gagaaggtga atcgaaagat gtaatgagct
     8041 ttgtacctac tccccatgaa tttatagtag ctccttctgc tttaagtgat gttatggtat
     8101 attcgtctag gtcattagat gcagtgatgc tgatatctga aaagccagca ttatctaatt
     8161 gttttttagc ttctttagat aaataagcta aatctccaga gtcaagtctt atacccatag
     8221 gtttgtatcc tttttcagaa atatttttga atacttttat tgcattagga actccactat
     8281 ttaatacatc ataagtatct acaagtagta ggcatttatc tggataaaca tcagcatatg
     8341 cttggaatgc ttcaagttca ttatcaaatt tttgaaccca actgtgagct tgtgtaccaa
     8401 ttataggtat atcaaacatt ttccctgcta gtacgtttgc agttccagca caaccaccaa
     8461 ctacggcagc cctagctcca tatatccctg catctggacc ttgtgcacga cgtaatccaa
     8521 attcaaatac agggtctcct tgagctgcaa agcaaactct agatgcttta gtagcaataa
     8581 gagactgaaa attaactatt gttaacaatg ctgtttcaat aagttgagct tgatataaag
     8641 gtgccttaac agtaattaat ggctcattag ggaacatgat agttccttcc tcaacagcat
     8701 atatatctcc tgtgaattta aattctttta aaaattttaa gaacttgtca gaaaataaat
     8761 ttaagttttt taagtactct aaatcttcat ctgaaaaatg aagattatct atgtattcaa
     8821 caacctgatc aataccacaa actatagtat accctccatc acaagcgttt tttctaaaaa
     8881 acatatcaaa tacaacaatg tcttcatgaa tattcttttc aaaatagcca tttaacatag
     8941 taagctgata taaatcagta agaagtgtta gatttctcat tatttctctc cttaattatt
     9001 attaaatatt aaaaattgta aaaactccca cacttatact aaaacataat atagtacaac
     9061 tttcaagtat aaagtattac ctaactatca taaaattatt taaagaggag gatgattata
     9121 ataggaaaaa tatggtttta tatggtatcg ataggaataa taggaagctt gatttctaaa
     9181 aatatgggtg aattaaataa agttatatta agtgaaacat caaaaggtat agagtttgca
     9241 ataagtctag ctggtatcat ggcactctgg atggggataa tgaatatcgc aaaagaatca
     9301 ggtttaattg aaaagatagg tcaaaaacta aatcctataa tgagaagatt atttccttct
     9361 attccaaaag gtcataaagc aatgtcttat atagttatga atattgcttt aaatatgttg
     9421 ggtgctggaa atggtgcaac agcatttggt ttaaaagcaa tgagtgagct tcaaactttg
     9481 aataacaaga aagatacagc cactaatgat atgattatgt ttatggtaat caatatatca
     9541 tctatacaaa taattccatt tactataatc aaattaagga tggatatggg ggctcaaaat
     9601 ccaagtgaaa taatttttac gactttattt gcaaccataa tatctacagc agtagcaata
     9661 ataacatgta aattttttca aagaagatat agataaaggg gatgtagata catggagata
     9721 ttttcaaact tacttatacc aataataatt ctgtacatag taatttatgg taaatataaa
     9781 aaaatagatg tgtatgatag ttttgtaaaa ggagcgattg atggattaaa agctgcatgg
     9841 gatatcctac catatataat aggtatattt ttggcaatag gaatattcaa aactggtaaa
     9901 ggtcttgata tgttagaatg gctatttaca ccaatagcaa atatgatgag tataccaaaa
     9961 gaattaatag gtctaataag tgtaaaacct ttatctggaa gtggtgcttt agggatgtac
    10021 agtgaacttg caaatagagt tggaatagga agtttagtag aaaaaatggg tgctacgatt
    10081 gtaggttctt ctgagactat tttttacaca atggcaatat actatggaag tctgaagata
    10141 aaaaatacta gacatacatt atcatgtgct atgattagcc atgttgcagg tgtcatagca
    10201 gctgttttta tttgctatgt aatatttgta taatttgttg acaatatggg aaaaatttta
    10261 taatatagtg attatataga aacaaatagt aatacaaatt acaagctatg aaaagaagag
    10321 taaataaagg ttttttctat cagagagcta ggttaggtga aagctagtgt caaaagcttt
    10381 attgaagatg gtcttggagc tttttatctg agcaagtgtg ctagggtaaa acggttggac
    10441 acgttatagt ctactaaggt atctataaaa tgtttctaca tttcatgtga aacataacta
    10501 ttatagatga attagggtgg taccgtgaat aatctcgccc ctatgttaac tcataggagg
    10561 cgatttttta ttatttaaat gaaagaatca tatgattacg aacgataaaa aattaggagg
    10621 taaataacat gagcaaaccg agtttttatg taacaacacc aatatactat ccaagtggag
    10681 gattacacat aggacatact tattcaacag tagctgcaga tacaatagct agattcaagc
    10741 gtttctgtgg atatgatgta aagttcttaa caggaacaga tgagcatggt gaaaaaattc
    10801 aaaagaaagc catagaacaa ggaatgtcag agatagagta tcttgatgga atgataaaag
    10861 atataaaggc cttatggaat actatggata tatcttatga tgattttata agaactacag
    10921 aaaaaagaca tacagacata atacaaaaga tatttactaa actatatgag caaggtgata
    10981 tatataaagg tgaatatgaa ggtagatact gtactccttg tgagagtttc tggacagaat
    11041 ctcaattact agaaggaaat aaatgccctg attgtggaag agaaacatat ttagtaaaag
    11101 aagaatctta tttctttaga ttatctaaat atgaagacag attaaaagag ttatttaaag
    11161 atgatagttt ctgttttcct gctgctagaa aaaatgaaat ggtggcaaac tttttagaca
    11221 aaggattaga agatttaagc gtaactagaa cgacttttga ctggggtata aaagttcctt
    11281 ttgatgaaaa acatgtaatt tatgtgtggg tagatgcttt atgtaactat ataacagcat
    11341 taggttatat gactgataat gatgaagaat ttaaaaaata ttggcctgcc aatgttcaaa
    11401 tagtaggtaa agaaatagtg agattccata caataatatg gccagcgctt ttaatggctt
    11461 taggtctaga agttccaaaa caagtatttg gacatggatg gatactattt gctgatgata
    11521 aaatgagtaa atcaaagggt aatgtggttt atccagaacc tataatagaa agatatggaa
    11581 tagacacact taagtacttc ttattaagag agtttgcatt tgggcaagat ggaagttata
    11641 ctcatagaaa ttttgtaacg agaataaatt atgatttagc aaatgattta ggaaacttaa
    11701 taagtagaac tgtagctatg gttgaaaaat acaataatgg tataatacca acagcaaaag
    11761 tttcaactga ttttgatgct gacttaaaag aacaagctgt ttcaactaga gaaaactttg
    11821 aagctgaaat ggataaaatg caattccatg aagcattaga gagtgtatgg aaattagtta
    11881 gaagaactaa caaatatata gatgaaacta tgccttgggc actagctaaa gatgaaacga
    11941 agaaaggtga attagacaca gttttatata atttatgtga atctataaga ataatcgcaa
    12001 cactaataaa tcctataatg aatgagactg ctaataaaat atatgaacat ataggaataa
    12061 aaggtcaaga tgatataact acatgggaaa gtacaaaaac atttggtctt attggagaaa
    12121 atgtaaaagt atttaaaggt gaacctttat tcccaagatt agatgtagaa aaagagatag
    12181 aagaattaac taaaatgttc tctgggaaac ctccagtaga agaaaaacct ttagagcata
    12241 aagaagaaat tactattgat gatttagaca aaatagagct tagagtaggg aaaataataa
    12301 gctgtgaaaa acatccaaaa gcaaataaat tattagtatc acaagttaag attggaccag
    12361 aaacaagaca aatagtatca ggaatagctg aatactataa gccagaggat ttagtaggaa
    12421 aagaggttac agtggtatgt aacttaaaac cagttaaatt aagaggtgta gaatctcaag
    12481 gtatgatatt agcagcaggt gatgatggag acccatatgt tttaccattt acacaagggg
    12541 ctaaagatgg atgcgaggtt cgttagtagg taattaaata gtaaggagat taaagatgtt
    12601 atttgactca catgcacatt taaatgatga aagttttgat gaagatagag atgaacttat
    12661 tggttcatta aaagataaag gtgtagattt ggttgtaaat ccaggagcag atatagagac
    12721 gtcgataaca gcaattgaac ttgcgaaaaa atacgacttt atatattcag cagttggggt
    12781 acatccacat gatgtatcaa aactagatga tacagcaata gaaactctaa gaaaacttgc
    12841 aactgagaat gaaaaagttg tagctattgg agagattgga ttagattatt attatgatta
    12901 ttctccaaga gaagaacaaa aagagtggtt taagaagcaa attgaattag ctaatgagct
    12961 aaaacttcca ataataatac atgatagaga tgcacatgga gatacttttg agataataaa
    13021 gaatactaaa aatcctgaaa taggatgtgt acttcattgt tatagtggga atgtagagtt
    13081 agctagagaa tatgttaaga tgggttgtta tatatcaatt ccaggcacgg ttacttttaa
    13141 gaataataaa aaaactagag aagtagtaag agaaatacct ctagaaagat tattcataga
    13201 gactgattca ccatatatgt caccagagcc acatagagga aagagaaaca atccttctca
    13261 agtatctttt gttgctgata agatagccca ggaaaaaggg atatgttatg aagaagtatg
    13321 tagagttaca aaagaaaatg caaagaaatt ttttaatata aaatagacaa attaaatctt
    13381 ataatgatat atataataag tcattataag tataggatga gagtgcctca aaatgagttt
    13441 tttagttcat gaggcactct ttttttatga aatcaaatat attttcatca tttcaacaat
    13501 gaaaaagaag tttattatat tttgagacag tttgtttttg tttatttaat tcatatttta
    13561 aaatatattt tcttaacatt gttaaaaaag aatttacaag atattcatta gaattaactc
    13621 aactctaata ttcacttaac ttaagttgtt tattatatta ttaaagagaa gtaaacgaaa
    13681 ggtagattaa ggaggttgaa ttttgtatac agttgatagt actaagatat tgataaatat
    13741 gaacttagag aaactagaaa agatatactc aatgataaaa gatacatcaa gtatttctat
    13801 aattaaagaa cctaacttgg ctacagtaat ggtaagagct aatgaaagtg taaaaaacac
    13861 aacatttaat ttaggagaga tattagttac tgaatgtagt gtaaaggtag atgaaagctt
    13921 gggttacgga atagtttcag aaaacaataa taagaaagcc atttacttag cagttataga
    13981 tgcagtttta catagcaata acagtaaatt tgatgagtta aagaattaca taaataaaag
    14041 tgtatatgaa gagaacttaa ggtatgaaca agagattatt gatgaattta gcttgattaa
    14101 taaaacgaaa gttcaattca atgctatgga ttaaatagga ggagaatcat ggtaaattat
    14161 acacaagaaa tatatagaaa gatgctagat agtgcttcat ttcctgggaa attaaataat
    14221 atagataata taaatataga aaataataca aaactattga atggagcaat tggtatagca
    14281 atcactttat tagaccaaga agttaccttc tatatagaaa attatactca aaaagatata
    14341 aaaaatataa gagcgcttac aatgtcaaat caaatagatt atagaaaatc agattatata
    14401 tttttagata ttaattcaga agtggatata ttacagatta aaataggttc ttttgaatat
    14461 cctgatgaaa gtgcaactat agtacatcaa gtaaatgatt tatcaacgta ctctcaaact
    14521 aagtatataa agcttgattt gagtggtcct ggtataaaat ctaaaaatag tatatatata
    14581 aatggaatta gagaagaatt tatagaaaga ttatctacca taaataaaga ttatccaata
    14641 ggaatagatt tgattttagt agataaaaaa ggagaaattg catttatacc aaggtcatca
    14701 aaattaagtt gggaggtatt gtagaaatgg cttatgtagc agttaaaggt ggagaagaag
    14761 ccatattaca ggctaaaaat atacttgagt tttatagggt aaaaggagat agcttgccta
    14821 tagatgtaaa gcagattgag gaacaaatgt cttatgctgt agacaaagta atgtctgaag
    14881 gaagtttata caacaaggaa ctatcagcat tggctataaa acaagctcaa ggtgatatat
    14941 tagaagcctc tttctatgta agagctttaa ggtcaacaat gcctagaatt acatattcag
    15001 aaccaataaa tacagaagaa atgagaataa aaagaagaat atcagctact tttaaagata
    15061 taccaggagg tcagtatctt ggggcaacta gagattatga aaatagaata ttgaatgtag
    15121 aattattaga agaagatgaa aaaaagaata gagattttag agatagtttt ataaatgaat
    15181 tagaaacagt agatgaaatc cctgaattta caaaaatatc taatatattt agaaaagaaa
    15241 atttattaca agaagaagtt tgtgaaaaca aattggaaga agttattgat gatattacaa
    15301 gaaatagttt aagatttcca gtttctaggt cagcaaagtt acaggcatta actagaggtg
    15361 aaagtggagt agtgtcaggt tttgcttatg ctattgtaag aggttttggt gatgaacatc
    15421 catatataag tgaacttaga actggtaatg tatttataaa agtaaaacat cccatctatg
    15481 aagatgaaga aataataata ggtgatatgc tggttactga atgtgaaata gtttcaaaag
    15541 catcacaaaa taagactgaa aattctaaaa ctaattcgga agataaaaat aagatgtctt
    15601 taggatatgg tctttgtatg gggaataatg agaataaggc tatatctatg gccatactag
    15661 acaaatcttt ggagccaaat agtgaaaaac tagcacaaga tgaagaattt gtattgcttc
    15721 atatagatgg aatagattca ttaggattta tatctcactt taagcttcct cactatgtag
    15781 attttaaagc ggatgtagaa agaataaaat agtttgtgga ggtaagttta ggtgatatat
    15841 aactatggtt ttttagacga aaacacaaaa aaagaaataa gaagaaagat attaaaagca
    15901 atatcaatac ctggttatca agttcccttt ggttcaagag agttgcctat agctaaggga
    15961 tggggtactg gaggtttaca attaacacta tcattaattg gtaaaaatga tgtagtaaaa
    16021 gtaattgacc aaggaagtga tgattctaca aatgcttgta atataaggag ctttattgca
    16081 agtgtaagta atgtagaaac cacaaaagat acattagaag ctacattgat tcaaacgaga
    16141 catagaatac cagaagaaaa acttaaatct aatcaaatac taatatttca agtgccaata
    16201 ccagaaaccc ttagaatagt agaacctagt gaagtagaaa caagaagaat gcattcagaa
    16261 gaagattata gtaggatgtg ggtatatctt tatgaagata tagttagatt taatgatata
    16321 tctatagcag ttgaatatcc atgtaaagta aatgatagat atttaatgaa tccatcacct
    16381 atacctagat ttgatataaa aaaattaaat atgtcagaca atttattctt gtttggtgca
    16441 ggtagagaaa aaagaattta tgctattcct ccatatacaa aggtagaacc tttagagttt
    16501 gaggattata agtttgaaga ggaaaagttt gaaggaaaat actgtagttt atgtaacagt
    16561 acaaatacat ttttagatga agtatatgac agtgacacta atgaaaagta ctatagttgc
    16621 tcagatacaa gttattgtga aaaagttaga ttaaaaaata acagtataga tgtgacaata
    16681 ggaggtactt ggaatgagta aaataaatga ctctaaaaga ttagaaaata tagacaagca
    16741 agtattaata ggaagaaata tcaatcttat ttatggagat gggtgtgaaa agtgttttga
    16801 aagcacagga tatgaaagca ataatatatg taagtattgt ggttctatag ttgcatgtaa
    16861 taatgtaaat ttagaacttt atgaaggaga agtccttgga attgtaggtg aatctggttc
    16921 aggaaaaagc actttattaa aaatactgtt tttccaagaa catgcaaata gtggagaagt
    16981 atatatatcc cattacaata aagacacaaa tatactagag ctttcagacc aaaaaaagag
    17041 atacataaag aatcatttta tgggtattgt gtatcaaaat ccccaccttg gtttaaattt
    17101 agactttagt agtggtggta atatagcaga aaaattattg atggcaaatt tatataatgt
    17161 tgaaaaaata agagatagag gcaaagaact tttaataaaa actaatatac ctgtagaaag
    17221 aatagaccat aaaccaaaat actttagtgg gggaatgcaa caacgagttc aaatagcaaa
    17281 agctctttca aataaccctc caatattgct attagatgag gttacaacag gtttagatgt
    17341 ttctgtgcaa gcggaagtat tggatttaat aagagaaatc caaagagaac ttaagatttc
    17401 tatgatagtt gtatcccatg actttgatgt tataaagatg cttgctgata ggacaattgt
    17461 aatgaaaaat ggaagtgtaa ttgagtctgg tcttacagac caaataatgg aggacccaca
    17521 acacccatat actcagcaac ttataaattc attgctataa atatcgtttg taaataagca
    17581 aaatgggggt ttttaataaa atgaaagaaa ctatacttga agtaaataat tttagtaaag
    17641 actttgagtt acatgcattg aacaagacta taacggcatg tagtaatata agttttgaag
    17701 tttcaaaagg tgagttttta ggaataatag gtaaatctgg agcaggtaag tctaccatat
    17761 taaaaagtat ctataaaaca tatataccaa caactggaga aataattttt aattcagaaa
    17821 tatatggtaa tgtagacctg gctaaaattg gagaccgaga aatgataaat cttagaaaga
    17881 aagaaatagg atatgtatca cagtttttaa agacacttcc acgaataact gcaattgaac
    17941 tggtagtaca ttctttaatt gagagtgggt ttgaaaaaga ttgttcgtat gatatggcaa
    18001 aagatatact taaccaattt gaaataaagg aaaatttatg ggatgcgtat ccaaataatt
    18061 tttctggtgg agaaaaatta agattaaatt tagctcaagc tatggttaaa aagcctagac
    18121 ttttgttact tgatgaacca actgcatcac ttgataatca atctaaaata tatgtaaaag
    18181 aaaaaatgtt ggagcttaaa agtcaaggaa ctacaatgat aggaattttt catgatatag
    18241 agtttatgga aactgttata gataagacct ttactatgac aaaagggact ataagtgaaa
    18301 gtggggtagc ctagatgata aaactaattc ataatgcaaa tattgtatta gaagatatga
    18361 ttttagaaaa tggtcattta atcatagagg gagatacaat aaaaaaagta tcaaatgata
    18421 agattgatta cgcatttgac tttaatgaga tagatgaaat aatagatgca aaaaacttat
    18481 atgtaatacc tggtattata gatattcaca gtgatgccat tgaaaaggaa atagagccga
    18541 gaccaagtac attattacca tttaatatgg cattttatga actagataaa aaactacctg
    18601 caaatggaat aactacagtt tatcattcta tatctttagg ggatggagta ggagttagaa
    18661 gtattgataa ctctttaaag atgattaaaa atattgattc atataaaaat atagatagta
    18721 agagcataaa tcataaagtt catttaagat atgaagtgtt gtattatgaa ggtttagaaa
    18781 aggttttaga actattagat gaaaataaaa tagactactt atcaataatg gaccattctc
    18841 caggacaagg tcagtataca aatccaacat tttataaaga gtatgctact aaagtgtggg
    18901 gagttacaga aaattatgta gatacatggt tagatgattt agtaaatctg catgataatt
    18961 tagattggaa taaaatagct aatattatag gtatagccaa aactaaaaat ataaatgttg
    19021 catcacatga tgatgataca ttagaaaaaa tggatttcat aaaaaatata ggcataaatg
    19081 tatctgaatt tcctataact cttgaagttg caaaacattc aaagaaattg ggtgttctaa
    19141 cttgtttagg tgcaccgaat attgtaagag gtaaatctca taataacaat ttaaaagcaa
    19201 tggatgctat attggaagat tgttgtgaca ttgtgtgttc ggattatctt ccatcagcta
    19261 tgataaagtc tatgtgtata gttgcagaaa gaataaataa tttaaataaa gcagtcagtt
    19321 tatttacctc aaatcctgct aaagcagttg gtatatatga tgaaagaggt agtataaaag
    19381 aaaataaaaa agcagattta gttttagtag atattgatag tgaatatcca aaggttgtaa
    19441 atactattgt aaatggaaaa acagtttata aaagggaggt ataaagattg ctaacagagt
    19501 tacattgtca tacaagtata tcagataata attttactac tgaagaaata ataaaaaaag
    19561 cagcagaaaa gaatataaat atcttagcaa taacaaatca tgacacatta tctggattgg
    19621 atgaagctct tgtgcttgga gagcattatg gaataacaat aataccaggt atagaaattt
    19681 cagcctatga ttataaaaat agaaaaagag ttcatattct tggatataac atagatttaa
    19741 acagtcaaga aataaaaaat ttgtgcaatc caatggtatg tgacagacat aaagcatctg
    19801 ttaagatggt aaataaaatt atagatttag gatacaaaat atctctggaa gatgtaaaga
    19861 aatattcatc aaagactgga atatttaaac aacatataat gaaagctctt atagataaag
    19921 gatatacaga taatatatat tcaaatctat ataaagaatt gtttcataga ggaaacggca
    19981 aggtatatgt atctttaaaa tatgtggatt acagagatgc aataaaagct ataaaaaatt
    20041 ctggtggaat ttgtgtgtta gctcacccgg gtcaaatgga taattttagc gctattgaag
    20101 agatggtaaa agtaggatta gatggaatag aagtatatca tccatctcac aacaaagaac
    20161 tagaaaaaga gtcgctttct tatgctaaga agtataatct agtggtcaca ggaggttcag
    20221 attaccacgg attttattct caacataatt atgaacttgg aagcaagagc ttaaataaag
    20281 aagatttatt taagtttagg ttagctttag gaggggtatt ataaatgtct tttttacaag
    20341 taaaaaatgt aggtaaaagt tatggacaag ttaaggtgtt aaaagacata tctattgata
    20401 ttgaaaaagg agagtttatt tgtttactag gtccaagtgg ttgtggaaaa agtacactac
    20461 ttagaataat tgcagggctt gaggataaac atggtggaaa aataataata aatgataagg
    20521 atatgactaa ttcaccacct gaaagtagaa attttggtat agtttttcaa tcatatgcat
    20581 tatttccaaa tatgaatgtt tacaaaaaca tagcctttgg actagaaaat aaaaacataa
    20641 gtaaatctaa tattgataaa aaagttaaag aagttctaga agttgtagaa ttaagtggat
    20701 atgagaaaaa atatccatca caattatcag gtggacaaca acaaagggtt gcattagctc
    20761 gtgcgattgc tttagagcca gactttttac ttcttgatga acctttatct gcattagatg
    20821 caaaagtaag acttaaactt agggagcaga ttagaagttt acatagaaaa ctaggcatta
    20881 caactataat ggtaacgcat gaccaagaag aagctctttg tttagctgat aagatggttg
    20941 ttatgaatag aggagaaata atacaagttg gaacgccaaa ggaggtatat aaaaatccag
    21001 aaacaccttt tgtagctgat tttataggaa caataaattt tatagatgat ggtattaata
    21061 agatagctat tagaccagaa gatataaaag tagagtctaa tagagattct aaagataagg
    21121 atataaaagt gggagaaatt ttagatatcg aatttagagg atttaactat agaattacag
    21181 ttgagtatcg ttctaagcaa atgaaattag atgtagtttc caaagttgca gaacaaatga
    21241 aactgtgcat aggttctaaa ataaacttta agatacctaa agaaggaatt gtacaatata
    21301 aatcagaggg atgtgcttaa tagctagggg tgaataaatg ataacatcaa aaaataaaag
    21361 aagaataagt gatagcacaa tacaaaaata tttcttgatt ttttcggtaa ttgtactaat
    21421 agtatttata ttatttccat tagtatcatt attaaaaaat gcatttatgg atacaagtgg
    21481 aaattttata ggaatttcaa actttagtaa atatgttgaa aatccaagtc ttatagcatc
    21541 atttaaaaat tcaatttttg tatctacagt ctcatcttta atatcactat gtttagcatt
    21601 tatatattca tacgcaataa caagaacaaa cataaagttt aaagattttt ttaaaactat
    21661 gggaatgttt ccactttttg caccaactat gttatatggt atttcactta tatacctttt
    21721 tggaaataag ggaatcttta caaccatggg tctggaagta ccactatatg gtccattagg
    21781 aataattatt tctcagattc tatttacatt tccacaagct tttttaatat tatctgtagc
    21841 actttcgatg gctgattata gactttatga agcagcagat agcttgggtg ctagtgaatt
    21901 taagaaattt tgcaaaataa caattcctgg tataaagtac tcattactta gttcattctt
    21961 tgtatccttt atacttgcat ttacagattt tggagcagct aaggtagtcg gaggaaacta
    22021 caatgtactg gctactgaca tatataaaca agtagttgga caatttaaca taccaatggg
    22081 agctactgtt tctatggtaa tgttaattcc tgtactaata gcatttacat tagataagat
    22141 ggcaagtaag aaacaaggta tgaccataac tgcaaagtct atgccatata agattaagga
    22201 aaataagttt agagatagag tatttttaat agtatgtagt tttataacat tgctaatttt
    22261 tattttaata ttcgtttcag ttataggttc agttataaag ttatggccat ataatttaag
    22321 ctttacaatg gaacactata catttaaagg tattttggga agtggaataa aaacatactt
    22381 gagcagtttg aaaatatcaa ctttaacagc aatatttgga actatatttg tattttttag
    22441 tgcttatatg atagaaaagg tggataagtt tcctaaatta agacaaacag cttacctttt
    22501 atcaatgata ccaatggcct tacctggctt agttttaggt atatcatata taactttttt
    22561 taactcagca agtaatccat taaatttttt atatggaagt acagcaatat tagttatagt
    22621 aaatgtagtt catttttatt cagtttgttt tataacctca aattcatctt taaaaatgtt
    22681 ggataaagag tatgaattag ttgcaaaatc cataaatatt ccattctata aagtattttt
    22741 taatataaca gttccaatgt ctataacatc aatacttgaa atagtagtat attattttgt
    22801 aaattcaatg gttactgttt cagcattaat atttttatat acacctcaaa ctcagactgc
    22861 atcaatatca atactaaagt tagatgagat aggatatata ggaccatcag ctgctatggc
    22921 agtattagtg cttttaacaa atataatagt aagacttttg tacgaatttg taacaaagaa
    22981 attaaaaaat aacacacaaa aatggcagca aaaagatgtt gcatagggga ggtaaaaatg
    23041 aaatttaaga agctagtttc tttaggagta ttatcaacac ttttattaag tgtaataaca
    23101 ggatgtagta ctgattcatc aggttcagat tcaaagtctg atagtaagac aaaaggggat
    23161 ttaacagttt acacagcaat tgaagaagat agtatagagc catatttagc tacatttaaa
    23221 gagaaatatc cagatattaa attaaatatt gttagggcat caacaggaga tataacagca
    23281 agattattag cagaaaagga taatcctcaa gcagatgttg tatggggagt tgcagccaca
    23341 agcttattgg ttgcagatga ccaggggatg ttagaaccat atgctccaaa aggttctgaa
    23401 gaaatagagt ctgcatttaa agatgataaa gaagttcctt cttgggttgg gatagatgct
    23461 tggatgacag gtataacagt aaacactaaa gaattaagtg ataagaacat cccagttcct
    23521 agttcttacg aagatttaat aaagccagaa tataaaggtc ttatatctat gcctaatcca
    23581 tcttcttctg gtacagggta tttaacagta tcagccctta tacaaattat gggggaagaa
    23641 aaagcatggc agtatatgga taagttacat gagaatattg gtgtatacac tcaatctggt
    23701 tcagctccag ctacatcagc agcttcagga gaatatccta ttggtatatc ttttggatat
    23761 agaggtataa agttaaaaga ggaaggctat ccagtagaag tagtatttcc aaaagaaggt
    23821 tctggatggg atatagaagc aaatgctctt gtgaaaaaag ataatataaa agaagcatca
    23881 aaagtatttt tagattgggc tataagtaaa gatgcaatga acgaatactc taagaactat
    23941 gcagttacta ctatttctac aggaaatcca ataccagaag gattccctaa aaagccatta
    24001 gagcaaatga tagataatga tttaaaatca gcagcaaaaa atagagaaga tatactaaat
    24061 aaatggatat caaaatatga tggtaagaca gaaaaagaga gttaagtaaa actatacaaa
    24121 tggagtaaaa agaaagaatt tttttaagta gattttatta taataatata agttgagaat
    24181 aatataggtc aagaaaagtg aatattctat aaaaatgtat agagtaagta taccattcag
    24241 tttgaatggt atatttttta tttttagaga ttaatttaga aatagatata ctacagttta
    24301 aaatagtata ttttaatttc attattaaag tatagatgtt ata
//
LOCUS       DAEQAF010000055        24136 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.057, whole genome shotgun sequence.
ACCESSION   DAEQAF010000055 DAEQAF010000000
VERSION     DAEQAF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 24136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24136
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.057"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     regulatory      249..350
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            423..1766
                     /locus_tag="KRN00_002313"
     CDS             423..1766
                     /locus_tag="KRN00_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH1828177.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            1945..3309
                     /locus_tag="KRN00_002314"
     CDS             1945..3309
                     /locus_tag="KRN00_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1828178.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(3487..5352)
                     /locus_tag="KRN00_002315"
     CDS             complement(3487..5352)
                     /locus_tag="KRN00_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBH1828179.1"
                     /translation="MENVFKRLQEFNSYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEDSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINDILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(5588..6805)
                     /locus_tag="KRN00_002316"
     CDS             complement(5588..6805)
                     /locus_tag="KRN00_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1828180.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAILIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(7005..7868)
                     /gene="aroE"
                     /locus_tag="KRN00_002317"
     CDS             complement(7005..7868)
                     /gene="aroE"
                     /locus_tag="KRN00_002317"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH1828181.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(7950..9872)
                     /locus_tag="KRN00_002318"
     CDS             complement(7950..9872)
                     /locus_tag="KRN00_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1828182.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(9951..10799)
                     /locus_tag="KRN00_002319"
     CDS             complement(9951..10799)
                     /locus_tag="KRN00_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBH1828183.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGTEEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     PEVSPK"
     gene            11212..12093
                     /locus_tag="KRN00_002320"
     CDS             11212..12093
                     /locus_tag="KRN00_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1828184.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(12301..13164)
                     /locus_tag="KRN00_002321"
     CDS             complement(12301..13164)
                     /locus_tag="KRN00_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBH1828185.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(13319..15253)
                     /locus_tag="KRN00_002322"
     CDS             complement(13319..15253)
                     /locus_tag="KRN00_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBH1828186.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(15365..16378)
                     /gene="galE"
                     /locus_tag="KRN00_002323"
     CDS             complement(15365..16378)
                     /gene="galE"
                     /locus_tag="KRN00_002323"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBH1828187.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(16402..17271)
                     /gene="galU"
                     /locus_tag="KRN00_002324"
     CDS             complement(16402..17271)
                     /gene="galU"
                     /locus_tag="KRN00_002324"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBH1828188.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(17469..17789)
                     /locus_tag="KRN00_002325"
     CDS             complement(17469..17789)
                     /locus_tag="KRN00_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828189.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(17779..19770)
                     /locus_tag="KRN00_002326"
     CDS             complement(17779..19770)
                     /locus_tag="KRN00_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828190.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKNMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(19893..22436)
                     /locus_tag="KRN00_002327"
     CDS             complement(19893..22436)
                     /locus_tag="KRN00_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBH1828191.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQDKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESVSQTIHNEYK
                     KLCGLEELHSVEGYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGVKEEIDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEVEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQKEPSQHIEEERNVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAQAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(22714..23048)
                     /gene="rnpB"
                     /locus_tag="KRN00_002328"
     ncRNA           complement(22714..23048)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KRN00_002328"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            23180..23857
                     /gene="srtB"
                     /locus_tag="KRN00_002329"
     CDS             23180..23857
                     /gene="srtB"
                     /locus_tag="KRN00_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBH1828192.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIIYGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(24017..24091)
                     /locus_tag="KRN00_002330"
     tRNA            complement(24017..24091)
                     /locus_tag="KRN00_002330"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24057..24059),aa:Thr,seq:tgt)
BASE COUNT         7724 a         4156 c         2716 g         9540 t
ORIGIN      
        1 aaaaagtttt tacgaaatat ccatgtattc agtactttta taattatatc acaaactcat
       61 ttataataaa cttccattaa tagtataaaa caagttagaa taattgacat tatactcata
      121 catattcaat tattggaaaa agtaattttt ttcaataaat aaccttaatt ttttataaaa
      181 tcgacaaaaa aacgaataat tttattatat ttattgtaaa taatacaata ttacgatata
      241 atacaacaga aaaacaaata gaaaatgttc atataatatt agtaatacgg tctaatagtt
      301 tctacaaact caccttaaat gggttttcta tgaatagaat gtcaactctg aatatatgtt
      361 ctattctatc tatatgaata tatatttttt tgtttatatc ttaaagtttt ttggaggtaa
      421 aaatggtacc aaacactaac aatgtacaac caggtggaaa taattcatca ttaagctttt
      481 tagacaaaat gtttaaattt agcgaacgtg gctctagcct taaaacagaa gtaataggtg
      541 gagttactac attcttaaca atggcataca tagttttcgt aaatccagca atattatctg
      601 aagctggaat ggataaagcc gcccttataa cagttaccat actagctaca gccattggta
      661 cacttatatt tgcgatttta ggaaatgcac catttgctct agctcctggt atgggattaa
      721 atgcattttt cacatactct ttggttatag gtgcaggaat cccatggcaa acaggtcttg
      781 gggtagtttt tctatctgga tgtgtcttct ttacactcgc agtaacaggt cttcgaaaga
      841 caattgcaga cgcaattcct agagaattgg cagtagcatc ttcagcaggt ataggtcttt
      901 tccttgcttt tgttggttta aaaaatatgg gtgttataat agctaatcca gatactatag
      961 tttcacttgc agattttaca ccaacagttt taatagccct ttttgctctt atcttaatgg
     1021 caatactaga atataaaaaa gttaaaggtg gaatattgat aagtatagta gttgcaacaa
     1081 taatatctgt tatatttgga tttgtggagt tgccaacagc aataatctca acacctccta
     1141 gtatagcacc agttgctttt aaattagata ttgtaggtgc attgaaattc tcattaattg
     1201 gacctatatt ctctttcatg tttatagaca tgtttgattc attagcattt cttattactt
     1261 gttgtaaaca aatgggtctt gaagatgaga atggtgaaat aaaagattta ggaagaatgt
     1321 tatatgcaga tgtttcttct actttaatag gttcattctt aggaactagt actgttacaa
     1381 catttggaga atctgcttct ggtattgcag caggtgcaag aacaggactt gcttcaatag
     1441 taacagcagc attattctta gctacactta tatttacacc attacttggt atagttccta
     1501 cttacgctgc agctcctgca cttgtaatgg ttggtgtatt catgtttgaa agcataaaac
     1561 agattgattt tgctgatagc aaaatagctg tacctgcttt tgttacagtt ttattgatgc
     1621 ctttaactta tagtataagt attggtttat gctttggatt tatttcatat ataataatgc
     1681 atgtagtagc taaagaaact gataaaatca gtattacact ttggattata ggtttacttg
     1741 cagttgtaaa cttagttcta agttaatatt tttaaatagt tctaggtcaa tattttaaat
     1801 tatatagaat aaaatcttat ttattttaaa tttataaata gcaaaatcac tttatatgta
     1861 aattgatttt gctattaact ttgtatagaa aatttattat cataatatat agatataaaa
     1921 atatatagaa aaggagtggt gtttatgtca caattactta taaaaaatgc atatctaatt
     1981 actatgaatg cagatagaga ggtatatgaa aatggaagca tacttattga aaataatatt
     2041 ataaaagagg ttggtaagtt tgatattaat attgtagata aagatgcaga gatatatgat
     2101 gctaaaggaa aaatactaat gccagggcta gtcaatacgc atgttcactt atctcaacaa
     2161 ttaggacgtg gtcttgcaga tgatgttgta cttttaactt ggcttagaga gagaatttgg
     2221 ccatacgaaa gtagcttcaa ttatgaagat tccttgattt catctactgc atgttgtgtt
     2281 gaattgataa aatctggtgt cactacattt ttagaatctg gtggtcaata tgtagatgct
     2341 atggttgaag ctgttgataa aactggactt agagcctgtt tagctaaatc agttatggat
     2401 acaggagatg gtcttcctga ggcatggcaa aaaactactg atgaggaaat caatactcaa
     2461 ttagacttat tccataagtt taataataca tctaatgaga gaattaaaat atggtttgca
     2521 ttaagaacta tttttaatac aactgaagaa ttacttgtta gaactaaaga actagctgat
     2581 aaatacaata caggtataca tatgcatatt gctgaaatag ctgatgaaat ttcatttgta
     2641 aagcaaaaca atggagttgg aacagttgaa taccttgata aactaggtgt attaggacca
     2701 aatcttttag ctgctcatac agtttggctt actcataagg aaattgattt atttagatta
     2761 catgatgtaa aagtttctca tgacccaggt tcagctatga aagtggttct agggtttgca
     2821 tcaattcctg aaatgttaga aaaaggaata cctgtttcaa ttggtactga tggagctcct
     2881 tcaaataata gaatggacct tatgagggac atgtatctta catcactaat acataaagga
     2941 agaactttaa acccaactgt cgtaccagct gaagaagtct tagaaatggc tactataaat
     3001 ggagcaaaat gtgctttact agaaaaagaa attggtagtc ttgaagtagg aaaaaaagct
     3061 gatatgatta ttctaaatcc agatacaatt cattgtttac caatgcataa tccaattgga
     3121 aatatagttt attctatgac tagtgaaaat gtagactcta ctatttgtga tggtaaatgg
     3181 ttgatgaagg aaagaaaagt attagttgta gatgaatctg aattattaaa taaagttaaa
     3241 aaacaagctt ctaaaataaa agataaagca gaagttaaaa ttccatctaa atttaaaatt
     3301 ataaaataac ataaatttca attgttttgt aaatatgaat atataaatat atttatatac
     3361 atcatatata caaaacaatt gtttttttat tttatattca ttagcattgc tcataaaata
     3421 caccataatt ccagaaaaaa taaccaatca gttaggatta catcatctaa gcaatatata
     3481 aacgtcttag tttataagtt ttattctact cttatctaaa accatcttta aagagttttc
     3541 aactgtttca attacatctt tataactcaa gtacacattt gcgtagatac aatcttcata
     3601 taaattatat tcagttactc tacaatacag cagttttcct ccatctaata aattgctcaa
     3661 aatatagttt tcttttcttg ggacatagcc tatcacatat ccagtttcac caactatttt
     3721 aatagctttt tcatcatata gattatcttt ctctctagtt aaatagtata tcttactttt
     3781 ctccaattct ttttcaagat attctctatt tctaaacctt gaaccagcaa cagctattga
     3841 agtcaaatag atatccttac catgttcatc tacttttatt ttttcaatat ttacaaattc
     3901 tttttttaaa ttattacttt catataatac tcttcttaat tcatccttca atataacatt
     3961 tttttctttt tcatacgctt ctttaacaat ttttaattct tcaagagata gtttctctct
     4021 gtatcttttt aagatattta tggattcttt tcttacttca tttatatttc caaatattcc
     4081 ttttaaagat atattctttc cttcaggata tagtgattta cttcctttaa gcacaataaa
     4141 aaataacata tcatcataat attcttgagt caatttatct ttttctatat ctttcatttt
     4201 tccaattaaa tcatctattt taaacgtctc ttcaaaaaaa tttaataatt ttaatctaga
     4261 acttgtcgtt ccctttttag atatatgcca atatacctca aaatctctaa tatctctatt
     4321 tagatatggc aacaagtcat caaaagataa gttcacatca taaatttctg acatttttat
     4381 aatatcttct gtttttccac tagcatctct taatgcttca aaatatatat ttttccattt
     4441 ttcactgagc aagatatcat ttatttcttt ttcaaattca atcttattgc actctatatt
     4501 ttcatctttt aagacgttta tagctattag gaaaattgaa tataaacttt caaagttagt
     4561 cccataattt actacagtag gtaaaaatcg attcactaat tctaatttat tacctatata
     4621 tttaaattct acacttagta agtaattgca tataagacgt gctaaattat ttatcttttc
     4681 tttatctaaa tctcgttttt caagatattc attcaaatct acaattgaaa taatatagtt
     4741 catcaataat cgttcgtact ttgtatcctt ataaccatct tcaattagat aggaatttat
     4801 tttagaatct aaattttcca tattaacaat agcaaatact tttattgaac ctgtagcctt
     4861 tttagataaa ttaaataaat atgtattgta aaattcaagt tttttaatag tattactcaa
     4921 ataaaatacg tattctccag atttagaaaa tgtatctaca acttctctta agttttctac
     4981 atttagatat ttctcactta aaactaaccc tagttttaca tactcaactt ttttactctt
     5041 atatattaat tctttagtta atttatataa ccatttctca tcaataatca tttcttttac
     5101 caaagtattt atctttttca taaaaatttc gaaataacaa attaaagact tagaattact
     5161 atcctccaat aaataaattt cattagattc acttttatac atatttaaaa tttcatctac
     5221 tagattattt gcaagctcta cttgttctct taacggtata ctttcatata tacataggta
     5281 attcatttca aatgattctt tgtatccatc ataactatta aattcctgca atcgcttaaa
     5341 aacattctcc accaaattat cctcctttac atgatgtaat ttatattgat tatactactt
     5401 atttcgtcaa gtttacattt atacgcaaaa aaatattact agaaattgaa attctagtaa
     5461 tatctttatt attaattatg taaataccct atcttataac tgtaaataat atccttatta
     5521 attttaatta cttttaataa aaacctatcc tagatttaga cttctctatg catatattat
     5581 actaatatta gacatcataa tcatacactt tttctttttc atatctcatg tttacaaaca
     5641 atgcaagtaa aattccaaca aatgttattg ccacattaaa caatacaaca tattttggtc
     5701 cattaactcc ccctgatttt gtaataatac ctgctatatt taaaataaca tagtttgcta
     5761 tactagatgc aatcataact atagatgtta tttttccttt attagttgga aacatttcat
     5821 ttgcagttga cgttgttaac tgaagaacac ctcctgctgc tgaataacct attacaaatc
     5881 cccctaacat acaaatagtt ggagtttgaa caaaatatac aactaatagc ataagtaaag
     5941 ctattatagg atatataact aatattctta ttggtttaat atatttttta ataagtaaag
     6001 aagttattaa tactgcacat attactccca ttgagtaaaa ggattgaatt tttgtagggt
     6061 cagccatccc atacaattta cccaattcct gattacaatt taaccataat acaaatgtag
     6121 atgtacatgt aaatccaata caaacaagag ctatacttgt tggtgtaaat ttcatcttct
     6181 ctgatttaac tgttttgcct ttgttatcaa taacattatt agctggtgga aatggtaaca
     6241 cagctatcaa aatggcatct actacaataa gaatcgctgt tactataaaa ataactttaa
     6301 atgatattga atttgctgca acaaatccaa ttataaaagg aagcaaaaat tgtgctaaag
     6361 ctattgtaaa tttagtaaac atatttgcta ttgttcctaa actagcaaat atctccatac
     6421 aagaaggggt tacacaggta tctaagaatg aatttgctgc ccctccaatt attgcaaata
     6481 catatgctat ataaaaattt ggtgaaaata caattccaac aaagaaaatt gcatgtagaa
     6541 agtttcctat aagaccactt acttttcttc catacttatc tgaaataggt cctgcaaatg
     6601 gataagatat aagtctccct aatcctagtg cagcaataac agctaaaaca atacttacat
     6661 ccaatgttcc atctgataat gttttagccc cccacattga tgaaaattct ggtttgtatt
     6721 gtcctaaaat tgaaattcca ataccaagta aaaaatatga aaaatacaac gctatggcag
     6781 taggataata ttttttattg ttcataattt ttctcccatt cttgttaatt tattaacatt
     6841 tttgtgtaca ataaactcat ccccataatg gatttaaagt atagtcagtt aaagcttcaa
     6901 atttaactgg actatgaggc aaaacccact atgacaattt gtaatttatt attaaaaata
     6961 ttgaaatacg tatgtttttt cattgtttaa gatattactc ttatctattt aaagcataat
     7021 tcattaactt cttctacagg catttctaat ccagtatata gattaaaagc ttctgctcct
     7081 tggtataata acattcctaa tccaccaata gccttacatc cattagcttc agcatcttca
     7141 atcatttttg ttttcttagg attataaacg acatctgtta ctactaaatc ttttcttaaa
     7201 acactagtat cttttatatt tgtttcattg tcataaggct tcataccaat aagagttgca
     7261 tttgtcaata tatcacttga ttgtatctcc tcataaagtt tgtttgtatc ttctaaatca
     7321 tatagattaa caacacattc tggtacatct ttttttatat tctcaactgt ttgctctgct
     7381 cttttataaa aatcatcctt aggattaaag atagatattt ctcttgctcc atctaaagca
     7441 cattgtactt gtatagcagt tgctgcacca ccagcaccca taattgtaat ctttttacct
     7501 ttaacttcta ccccattttc ttttaaatta cgaacatagc ctactccatc tgttatatga
     7561 ccaactaact ttccattgtc atttacaatt gtattacatg ctccaattat acgagctgct
     7621 ggagaaagtt catccatata ttctgtaaca gcagatttac atggcatagt aacattggct
     7681 ccttttatat taaaagtttt tattgctaaa agtgcctctt ttaccttatc tactgtgata
     7741 tcaaaggcta aatatctata atctaaatct aatttcttaa aactataatt atacatcact
     7801 ggtgatttag agtgaccaac tggtgtacct attaatgcaa ataatcctgt tctacctgaa
     7861 atttccataa ctataatctc ctcccaatat tatcattttc tttgcaaata acctattcag
     7921 ttatttacaa agaaaaattt atttattatt tatatattta atgctacttc aaaagcttct
     7981 tttgttgcat ctaatgccct acgagctttt actgcatcac caacaatata agtttctttt
     8041 acaacttctt ttataacttc acttaatggg tcgtaattac gagaacccat agcaagtact
     8101 actgaatcaa aaccttttaa atcatgctct gtgccatctg taagtaaata gtcgacacca
     8161 tcatcataaa atttagaaac ttttgcacca gtaatggtat gtatattata attttcaaaa
     8221 tcattcataa ggaatttacg gtgttctgaa attacatctg caccaacttc ttctctaagc
     8281 tcaataacag taacctcatg ttcttgttct ccaaggaagg ctgccacttc acatccaacc
     8341 attccacctc caacaacaag tacttttttc ccacaagatt ttttaccatc aagaaggtct
     8401 acagcatgaa ttaatcctga atcattgatt cctggtatag gaagtacaag tggagttgct
     8461 ccagtagcta taataactac atcaggtgat ttctccttta taagttctac tgtagcttct
     8521 gtattagtac atatttttac accatattga ttacattttg aaatataact tctaactaag
     8581 ttagtaatat ctccttttcc tggaggatat gcagctaaac gcatttgccc accaagaact
     8641 tcagattttt caactaaagt tacattatgt cctcttttag cacataccca tgctgcaagc
     8701 atacctccaa cacctccacc aacaacaaga acttctttgc taatttcagc tggcttaagc
     8761 tctgcttcat gtcctaatat aggatttgca agacaggcta taggtttgcc ttggaacata
     8821 tttggtacac atccttgtaa gcatgcaata catggtatca tttcgtctag ttttccattt
     8881 ttagctttat taggcatttc tggatcagcc aagctttgtc taccgaatgc tactaaatca
     8941 catcttcctt gtcttaccat taactcagca aactgtggct ctgtataacg tccaactgtt
     9001 attactggta tactaacagc tttttttatt tcagtaacta attctgcact gaatccagca
     9061 tgtaaagtcg taggagccca catatattca tcatgtatat gtatactacg tgaaacatga
     9121 agtccatcta ttccacaatc ttctagatat gctgctatta ctgaactatc gtgtacatca
     9181 attcctcctg gaacatcatc agtactgttt atgcgacata atattgctag agaatttcct
     9241 acttttttac gtatattttc aatgataaga cgaggtaatc tcattctatt ttcaaaacat
     9301 ccaccaaact catctacacg cttatttgtt ctttgtgata taaaactact gaccagatat
     9361 ccatgagcgc agtgaacttc aacagcatct gcaccagctt tttgtgcacg taatgcagca
     9421 tctccataag attctataag ttcatatatt tcttctgttg ttattgctag tggtgtatta
     9481 cgaccatttg atgcaggtat tgcagaagca gcttttaatg gatgtcctgc tactttttca
     9541 tttccttcag aaccagcatg ttgtaattgt atagatacct tcgaacctgc atcatgacaa
     9601 gcatctatta catttttaaa actatctatt gtgctatcat catataaaca aggcttacga
     9661 ggacctcctt ttgctttttt gtctacaaca ctagattcta tagttattaa tccaaaacca
     9721 cctaaagcac gctcaagata ataagcctta gaagtttcac ttaaagtacc atctgtgttt
     9781 gcaaaattgt ttcccatagg gggaactaca aaacgatttg gaactgtcat tgaaccaatt
     9841 cttataggtg taaacataga actaatcttc ataaggtttt ccttcctttc aagttttata
     9901 tttaaaagtt ttatattata atactctgta tatttttata ttatataagt ttattttgga
     9961 gatacttcag gccatgcttt atccaaaact tttttagttg cattaaatac agtttcagca
    10021 gcagtggata accctttaga tattagagaa tcagatatta cttctgcccc tatgactctt
    10081 ggtgatatat tgtgttcttt tattattttc acaaattcct ctgtgtttcc atatccttca
    10141 cctggagcca aacggtcatg tagtgattca tccctaagtt tttcataagg agtttctaaa
    10201 acatcacaca cttgaattga tactatctta tctgctggaa caggtgcaag gtcctctgct
    10261 gtctgctttg ctctagccca gtgccaagta tctaatataa gcattgcatt ttcacgatta
    10321 catcctttca caacacgcca tgcagtagcc aaatctggta caccactata tggcataaac
    10381 tcaagaccta taataagttc acctgctctg tcacataatt ctcccaatgc agttataatt
    10441 tgttcttctg gtatcatctc taataatcca caatttatat gtttaacatt aaataagtga
    10501 gccatatgat aaacattttg ctctttttct ctttgagctt ccgttctatc ttcttctgtt
    10561 ccccattgag ttatatattc tacttctgta actttcatat catattcatt aagaattgca
    10621 atcatttctt catctgtaac acctgcattt tttgcatcaa tataattttc agcacgcaat
    10681 ccaataccat caaacccagc ttcttttgca atacgaactc tatcacggaa tgaaacttct
    10741 gttcccaatg tataagaact aattgtaatt ggaatattaa gatttttttg attattcata
    10801 gcttaaattt gcccccttta ttttctttat aattaatagt atttttgatt ttatattttt
    10861 atttatccta ctagtagtat tattttgcct taaaaataaa agtatttttt gatttctatt
    10921 tatctagatt ttataaattt attgtatcac gagactttac taataacaaa ttgataattt
    10981 cctattaatt catagatttt gtttatagat tttatttata agataattct tgtatttttc
    11041 tattaggtcg tataaatata tttatcttat aattcagaca aaaaacgata aactttttta
    11101 aaagctttta ttcttactat ataatcatat ataataaaaa tgtaaaaata tcttaaaggt
    11161 taacttctac aaatatataa ataaaaatac ctatgaaagg atgaacaaaa attgaattta
    11221 tatcacttac gctattttgt tacattggca catttagaac actatacaaa agcggcagaa
    11281 aatttatcta taacacaacc aagcttaagt catgctattt ctttactaga aaatgaactt
    11341 ggggtggctc tatttgaaaa agaaggtaga aatatagtcc ttactaagta tggaaaaata
    11401 tttttaaaag atgtggaaaa atcattagaa attttagatt caagtgtaaa atcattaaaa
    11461 ataactggta ctggtgaagg acaaatagac ttagcttttc ttagaacact tggtactgat
    11521 tttatcccag acatagtgca taaattttta aaatctaatc ctgctaaatc aatagatttt
    11581 aaatttcata ctggtgtaac tactgacatt attcaaggtc ttaaagaaag aaaatatgat
    11641 attgcatttt gttcgaaact tgaaaaagaa aagggaattg aatttatacc tgttgccaaa
    11701 caagatttag tactaattgt accatatagt catccactag ccgcaaagga tactatagat
    11761 ttaaaagaaa ccatacctta tcctcaaata gtatttaatc agagaagcgg tcttagatat
    11821 ataattgatg atatgtttaa aaaaataaat caacagccta atatagtcta tgaagtagag
    11881 gaagaccaag taattgctgg attagttgca aaaaatttcg gaattgctgt agtcccaaat
    11941 atgaatatgc ttagctttac aaaagtaaaa gtaattcaga ttattcaccc aagttgggaa
    12001 agaaactttt acttagcatt tataaaagat agatatttgc ctcctgcaat taaaaacttt
    12061 aaaaactttg tcattaaaaa cgctcaatta taatttatta ataaaggggt tatttttaaa
    12121 tatcctcttt tattcttttt ataaaataaa aaaatctata cttttaaaag tatagattcc
    12181 taactgacag tcggcatccg agtctcagta attatcgtta tacaacagca actggattca
    12241 gttcctgaat aactaggtta tttacattat atcagatttt ttaaaatttg tcaattgtat
    12301 ctaacgcatt ttttcaagcc atggtccaac aggctctaca ataggaactt ctttaaatcc
    12361 ccaatttctt atatcattca cactcgttgg agtatatatt ttgtttctga cagatttgaa
    12421 tattttgttt ttttctccat attgcataca ctttggatta gcttctatta accctcttct
    12481 tgctctgcta agaggattac ataaaatatc tgctatttct aaaccttctc tatagtcagc
    12541 atcttctttt ttggcaatta taaaaccctt aaccttatct cttaattctt catctatatc
    12601 taagtatatt gttccattat taaatacatc aaaaaacgcc ttttgtactt ttaagtttga
    12661 gacatcatcc cttgactcta taactattcg tgcagattct acagtttcat tatttacaaa
    12721 tgaataaaaa ttctgaagaa catgtataaa agccacaaca tacggttcct ttgaaggtgc
    12781 ataatatttc tttaatctag ctttatctac tgttactgat attatagtac actctaatct
    12841 agatagaaat aaaggcaact catcatagaa taacttaatc tgtgaatcat caaacttctc
    12901 aaatgctctt gattttcttg atatatctgt caaatgtatt cctatgttac tggttccaaa
    12961 acaatactct ttaaacgcat ccatttcttt cctcaaagaa catacataat cgccttgact
    13021 tactgcatat ttatattcaa aaattactcc tgtcaatgta aatgggtctt catgatttat
    13081 atcagctctt ccactttcat caataaacat tatatatttt ttctttataa tcttactcac
    13141 cctcttaaca tatgatgata gcatctatat tcattttata tgagttttaa aaatattcca
    13201 agatttttat ataacttaaa cttaatttta tactaaaaaa ttgagatgta aaacaatcaa
    13261 gcttttattg attgaatttc acatctcaat tataattatt tttcaatata tgtttttact
    13321 attttgcaag aatatccatt aatttatcca ttactatata agataccccg cctcctattt
    13381 gataaggagt ttcaactttt ttatttgcaa atactctttg ttgctctgat gataatcctg
    13441 aattatccat taaaactatt ggtgaatgta attttacagc taatggtcca gctgataaag
    13501 catctactaa agcatctgat ttactaacta atacagcctg taaatcagta tctccataga
    13561 atttttctat tactttggca ttagtatcta ctctactatc tccatatatt ctatttcctg
    13621 aaatatcttc agtagttata tcattcattt ttgctattac tgaatcgtta attgcacttg
    13681 gtccacctat aaagtatgca ttttctaatt ttctttctgt tagccattta taagattctt
    13741 ctgtaattcc atctttattg actaatatta taggttgttt ttcttcccca gctttagaag
    13801 ctacagataa agcatctgct tccccatttc cagaaaccat atatgcagtt tttatttctt
    13861 ctcgatttcc aagttcttca gctattcttg tagcagtttg atatctatct tgacctgcta
    13921 ttctctttgt ttctgtgttg aaagtagttt ttatttcttg ctctaattta gaacttattg
    13981 cattttctcc acctatcaaa attactgttt taggtgctaa taacttcatt tcttcaacag
    14041 tttcagttgg taaattagct gtattagtaa gtagtattgt tgagtcatag ctacttgcta
    14101 aaggagttgc tgttatacca tcagctattg cattaccatt tactaatatt acagtatctg
    14161 aactatcagc attccagttt ccaactgaac ttatcttttt agctgtatca aatctatttg
    14221 cacctataat tgtatcccat gtaggattta tagttccatc ttcattaaaa gtataatctt
    14281 tcccatctat tttttgagaa ccagttagca tctttccatc tttgtctaaa tagtaagact
    14341 taccatctat ttgttgccat cctgtctgca ttattcctgt tttgtcaaag taatacttat
    14401 taccatctat ttcttgccat cctgttactg ctaaaccatc agatcctaga tagtatttct
    14461 ttccattctt ttcttgccat cctgtttgca ttactccatc tgagttaaag taataagttt
    14521 ttccgtctat tactttccat ccagatactc ttgctccatc agttcctaaa taatattttt
    14581 tgttattaat tgttttccat cctgtttgca ttactcctga agcatcaaag taatacattt
    14641 ttccatttac ttttagccaa ctattctttt ggtatgttcc atcagatttt acataatact
    14701 tcttaccatt ttctgttttc catcctgttt gatttagatt tatcttatat tttgcggcta
    14761 tctttacata gctgtcatta ctataatcta taattacatc tgaacctaca ggaacttggt
    14821 caaataacca tctaacatct ttattgtgca ttcttataca tccaccagaa atatgctttc
    14881 ctatagaact ctcattatta tttccatgta ttccatatgt atctccataa gttcctttta
    14941 atgctaatcc catccatcta tctcctaatg gatttcttgg acttcctcca ggtatattac
    15001 ctttataata tggtctattt tttatcttgt taactacttt tgttttccct gttggtgttt
    15061 ctgacccctt tttacctgtt gcaactctaa attcttttac aagtttatta tttacaaaat
    15121 atcctagagt attttttctt gaatttacta taatcacatg tttactggct gcgcttgatt
    15181 ctggtacgcc acatgcaaat actaaaacta aagtcagtgc tagtactaaa tactttttta
    15241 gacttttttt cactataact tccccctctt ttagaaacat tactacatgt gtctaattat
    15301 aacataaaat taccaatacc ttatatttac aaatttgtta catttataca tataagtata
    15361 tattctattc ttcataccca ttaggattca tactttgcca tctccatgaa tcttcacaca
    15421 tctcttcaag ttcatactta gctttccatc caagctcttt ttctgccttt gaagaatctg
    15481 cataacacat ggctacatct ccagcccttc ttcctacaat cttatatggt atttcttttc
    15541 cacttgcttt agaaaatgct tttactaaat caagaacact ataccccttt ccagttccta
    15601 aattataaac aacaagtcct ggattttctt ctaatttttg taatgctttt acatgaccag
    15661 cagctaaatc taatacatgt atatagtctc taactccagt tccatcatgt gttggatagt
    15721 cattaccata aacactcaat tccttcaatt tacctactgc tatttttgtt atataaggca
    15781 ttagattgct cggaactcca tttggttctt cacctattct accactttta tgagcaccga
    15841 ctggattaaa gtatcttaaa agagctatat ccaatgactt atctgctttt gatatatcta
    15901 ctaacatctg ctctatcata agtttagttc ttccatatgg attggttaca gaaagtggga
    15961 aatcctctaa tataggacaa gtatgtgggt ctccatatac agtagctgaa gaactaaata
    16021 caaacttttt aacaccatat tctctcatta attcaaataa atttaaggta cttattagat
    16081 tattgctgta atattcaatt ggtttttcta ctgattcacc aactgctttt aaagctgcaa
    16141 agtgtataat tgattcaata ttattttctt taaatacaac atgcatttca tctttatttc
    16201 tgatatcaat attataaaat tttactggtt ttttagataa ttccttgatt ctatcaacca
    16261 ctattgagtt gctattactt aagttatcaa ctataacaac ttcataacct gattctaaaa
    16321 gttctattgc tgtatggctt cctatatatc ctgctcctcc agctactaaa actgccattg
    16381 taattacctc ttttctaata tttatttttc acttactttt tttctcatat agtccattaa
    16441 atcatctttt aaattttctc tctttagagc aaagtctatt gttgcctcta aaaaaccaat
    16501 cttatctccc acatcatatc ttctaccttc aaagttataa gcataaatag cctcttgttt
    16561 tccaagagtt tgaagtgcat ctgtcagttg tatctctcca cctttaccag gtgtctgttt
    16621 ctctaatatg ctaaatattg caggagttat tatatatctt ccaagtatag ctatatcaga
    16681 tggagcttct tcaattgcag gtttttcaac catatcttta actttatata ctctatcttc
    16741 gatatgtttt acatccaata taccatattt attagtatct tctttagcta tcttttgaac
    16801 acctaataca gttgttttat actcattata agtatctatt aattgtttta agcacggaac
    16861 atctgaatct actatatcat cacctaataa tacggcaaaa ggttcatcac ctataaaact
    16921 ttttgcacag taaattgcat gtccaagacc ttttggctct ttttgtctta tataatgaat
    16981 atttaccata tttgatatgt ctcttaccat ttctaacatc tctgtcttac ctttttgctc
    17041 tagttctaac tctaattcaa ctgatttatc aaaatgatct tctatagatt ttttatttct
    17101 acccgttatt ataagaattt cttcaattcc cgattctata gcttcttcta ttatatactg
    17161 taaagttggt ttatctacta taggaagcat ttctttgggc tgtgattttg ttgctggtaa
    17221 aaatctagtt cctagccctg ctgctggtat tattgctttt ttaactgtca tctgcatttt
    17281 ttcacccttc ttcgtaaatt ttctattgta ccaaattaat ataccatatt tatacttttt
    17341 cttcaaactc tatattatcc caatatttaa tgctataaga taatataagg tagatgaaat
    17401 ttcatctacc tttagtttta taagttaata ttgtattgtt tatattttat ccaaaactta
    17461 tacaggtact aaatttcatc taagatgcct tttatatcac tatctatatc ttcatctaga
    17521 taagaatcta aatcttctaa gtcaacttct agttcttgat atgtcatatc aacactgaca
    17581 tcctcatcta tatccatttc tgatattaat tctcctaaaa tactatttcc atcagaatct
    17641 aaaccactat ctatatcttc atctatatag ttttcattta aaatttcatc taaatcaatc
    17701 tcgtaataaa cttcattatt tttttcatcc cctgagtcca atcctaagaa ctcatagtta
    17761 aaagtccaaa cattgtattt acttgacata ctttattcct cctgtgaaaa acatattttc
    17821 atctagttta ttggttccat aatcaacaga gttatatatt ttttcaatta tgtcttttct
    17881 tctttctttt gtactattat ttaatgtcaa ttgtttaaat acatatgtat ttgttattct
    17941 ctcgaataat atttctttta tactatcatc atcaatattt ctatagtttt tccacaataa
    18001 ctcaaataac ttaaacattt ccctactagt ttcatctaca taataaggat acatattttc
    18061 tactaaatgg tttaatcttg atatggcttg ttttaaaaat acatcaagac ttgcactttc
    18121 actttctttt aacattctat aattgtattt cttcttatct tctcctgaaa ttacaaagat
    18181 gatattatct aaactttttt caacttcatt taaataactg cttatattat atgataagtc
    18241 agacaataga tttttaatct gcttaaacac ttgtacatca agtttagtat tatacttttc
    18301 aaacaaatct atttcttgat tttctaatat tcttggcata tatgctgaca ataaatctaa
    18361 attgtttctt tgttcttgta tttgcttata aagtgaattt ataacttcta ttcttatttc
    18421 atcatttaac tctttttcta aaatcttatc aaattcagat ttcatatagt aaatatttcc
    18481 aaagaaatta aatattatca tatcattcat agctttagac caattcttat atatcacttc
    18541 aatagaattt tctttaagta gaggttgctt tgcatatata aatacatctt gcataagttt
    18601 ttgaaccata tttttactta agtttaaaag tactttttga ttattaaatt ttatttccgt
    18661 ttctacaaaa ttagaatttt cgttttcaag ttctttatta attacaatgt cttttatatc
    18721 actatttttt atagatatga tttctttttg aaaagacttt agaatagtca agctatcgaa
    18781 atcttcttga ataaaaaatg gagcatgttt taatgtatat cccactattt cattttctat
    18841 atcttttaag tcatctattt gcataatttc tctattttta tcatttatat gtaggttaaa
    18901 tacattttta ttatcatata atattatatc ttctcctaaa tttaacttag aacaattatc
    18961 tttcgctgac tttacaatag tcttcttaga tttcttattt ataaaaatta attggtcttg
    19021 atattttact aaaagcatgt ttgtgttttt ataatcaaat ccatctatat ttcctgatat
    19081 cttgcagaat actatttcac aatctttagg aagatttcct attttttggt tatctttaac
    19141 tctctcattt aaatcagatg ggactacact atctatattg ttattaaata tagatacaga
    19201 ccttactata atcccctctc tttccatatg aaagtatccc ttcaatgaca ctcttttatc
    19261 ttctaaaatg tatctttcta tatcatcaaa atttatttca aatctatttt tcccactgat
    19321 aaatataaac ttctcattat ctttattaat tccacccata taaaacttat tgtcatctaa
    19381 acttaatata gtcatattat cctttagata gaatataaat tctctttgac ttttgcagat
    19441 taaatcatat tcatccaaag ttattttcat agtcaaattt gctgtaacat ttttacttga
    19501 attttcactt tttatgtaaa aaggcaagtt atttccatag acaattattt gagaatcttc
    19561 taaaactgcc tctaattttt ctttattgtc tgaaaaacta tatatatatt ttacacctgt
    19621 atcctcatta acttcatctg atttgctgat tattatattc cctagatttg ttatatgaag
    19681 ctttttatat tcttttgagt atctacttat gccactaagc tcaaacccat ctgaaagctc
    19741 atatatgatt ttttctccta atttcaacat accttcacca cctaaacaga attataagta
    19801 ttttataaag gtgaataaaa tgtctcaaaa caaataatat tttttttaat actttttatt
    19861 ctgagacata gtttctcctt ttttataatg ctctaagcac cttcaactat ttcttcataa
    19921 agtttatcta aatgtttaac atattcacga tatccagatt tgttctttaa ctcacttctt
    19981 aaatcttcat atttttgttt aagttcttca gcactcaaag aaggagctga ttcttttaat
    20041 tcttctaact tataatcata gtacttatca tacatagcta tatatgtatc aatagacttc
    20101 ttagctagtt cattacattt ttcttgtgct tctccatatt gagaataatc acctattttt
    20161 attttatagt atccattttc ttgaattatt gttgaagaaa tacctttagc ctcatattct
    20221 tttgctgttt cttttgctgt tttttcaact ttaagtgaac ctgcataaac agtgtaatat
    20281 acacctttac catctttata tgcttccatt tcttttgctt tcttttcagc ttgtgctttt
    20341 tcttgagcct ctttttcagc ttgtgccttt tcttctgctt cttttttctc tttttcagct
    20401 tgtgcttttt tctcttcttc agttaattta ttgttagctt gttgttgagt tgatgacttt
    20461 ggaatattct ctttatcatt tttcttattg ttgcctactg ttataaaata tcctacacca
    20521 acaataacca ctataactac tgctataata gtttctttta atctactctt cttagaaaca
    20581 acctcttcat catctaaaga atcttcttta tctgatacat aatttttcat ttctttcttg
    20641 ttttctctat atttgtcctt agaagaattt ttagattttt tattactatt ttctttcttt
    20701 ttaataggta ttactactga tttttcattt tctaattttt cttcttttat ttcttttgct
    20761 tttttatctt ctaagttttt actttctttt tcaagcttcg attcattatt tgaagatact
    20821 ttttcatcta agttattatt tattggtttt tctattttta cattacgttc ttcttctata
    20881 tgttgacttg gttctttttg ttttatttct tttaattcat tttgctctat ttcttctgat
    20941 tttacttgat gattttcaac tggtttatct aaaattatat caggagaaat atcatttaaa
    21001 ttctcttctt cttgttcaac ttcttcattg tcttttttaa taaatccaaa taatttagcc
    21061 ttctttttac tctttttatt ttctggttca attatatctt ctttattgct gtcgtactct
    21121 ttatctgtag tatctttatc ttctacaacg tcacctatat cttgattatt actatctatt
    21181 tcttctttaa ccccttcttc agcatcatct tctattgaaa tactacttct aaagcaaata
    21241 tctttatctg cattttttat catgtaaatg tattcttcaa tatcgatatc tttatttctt
    21301 ctagttcttt ttgatgcaat ttcatgattt tctaattcac tatagttatc ttttattaga
    21361 ttctgtgctt tattccatgt atcttcacta atttctgttt tatttttaat tacatagtcc
    21421 acaaattcct taaaattttc aggaccaaat tctccaatta tagtcagtct cattgcacct
    21481 tctataaggt ctctatttct tctctttaaa aattctaata caaccgttgc acaagcaaaa
    21541 tctttaataa tttctttgcc aaaaccatat ccttcaacag aatgaagttc ttctaatcca
    21601 cataacttct tatattcatt gtgtattgtt tgagatacac tttcattatt taagctattt
    21661 aacttatcta taaacttcga ttctatatca tttgattttg attcatgttt tacttttgaa
    21721 tttttaattt catttagtag catgtcattt tctgaattat ctttacctaa ttgcaaatcc
    21781 tcaatttcag ttgcttttat ttctactttg tcttgttcgt tattctcttc cacattatta
    21841 ggtaccacat ctttattgct agctaatatt ttgtttacac agaatataat ttctcttttt
    21901 aattctcttt tcgcatctgc ttgattttta agaaataaat ctccacattc tttcttttct
    21961 aaacttattt ttctaagaga tatattaaga aggtctttat ataggtttaa aaccttataa
    22021 tccttttcta aacgtcttct tctctctgat agttccattt tatcataagc taaaaaacta
    22081 tttaaatcat tggcttttag agagtctaat ccctctttca tagccttatt tacatacttt
    22141 ctacattttg ctgtagttaa ttctaaatct ttttctaatt catctatttc aggtatgtac
    22201 ttatctacta tccatttgcc aataagtggt tctgtatttc ttgctaatgt cttataaaac
    22261 aatatattaa attttaaaag ctctgcatat tttgcttcat taaattctac tttttcaaat
    22321 ttcttttcca aaacaccatc tagcttttca tttattttag actcttgttt taaaaaactt
    22381 gctgtgacat ttaaaacagt gtttcttatt atattatttt cactcaaaac cttcactcct
    22441 taaatcaatt attttattat aatatttaca ttgtgcaaag ttgctaattt gattatgata
    22501 tctaaataat tatttactaa atttgctaca tcttatatca tatcatatta tttacatcat
    22561 tttacttttt ctttttatat ctatcttata ttataccatt tttaatatct gtactaactt
    22621 atattacaat attcctcaaa attttaaaag tagattagac aaatttacaa ataaaaaaac
    22681 atcagtttaa actgatgttt ttgactatcg aaataattaa gcaagtctat aagcggagtt
    22741 ctgtattaga taatcatctt tctaggccta ttgtcaccaa taggctcaag cgacctacct
    22801 accggagagt acgagcagca ctctttattc ctatcttggt cttgctccag gtggggttta
    22861 catagccaac tagtcgccta gctgctggtg agctcttacc tcgcctttcc atccttacca
    22921 caatagtggc ggtttatttc tgttgcacta tccttaggat cgctcccact aggcgttacc
    22981 tagcaccctg ctctatggag ctccgacttt cctcatgtaa gattacatgc gattatctgg
    23041 cttacttaat atttatttta cttagttatg ttaacacaaa ttcttttaca tgtcaaagta
    23101 atattatact aaaaatttaa atttattcaa aaatagtgta atatagatat ataaactaca
    23161 tttaactcga ggtgatatat tgaaaaaatt atatagaata gtaattaaca ttatactagt
    23221 attagtaata ctttacagtg gatttaatat atactcaaaa cttactaaat acaatcatga
    23281 tactaaaata tcctcagaac ttcaaaaaaa agaatataaa aaagaggatt tatcaaaaat
    23341 taacagtgat tttaaatttt ggctttctgt tgagaataca aatataaatt atccagttgt
    23401 acaatctaaa gataattctt actatcttga caaagatttt tataaaaaag attctatttc
    23461 tggtacactg tttatggatt atagaaataa atctattgat gacaaaaata tcataatata
    23521 tggacataat atgaaaaata aaactatgtt caacaaccta aataagttta aagatgctga
    23581 cttctttaaa aaaaataata aaataaaaat aaccttgaat ggaaaagaat ttttatatga
    23641 tgttttttct gcttatattg tagaatctga ttatgattat ctaaaaacaa attttaataa
    23701 tgaatctgat tatcaaaatt acataaatga tattacttct aaatcattgt ataaatctcc
    23761 tattaaggta aatagcaatg ataaaatagt tacactttct acatgtacct atgaatttga
    23821 tgatgccaga atggtgattc atggtagatt gatttaaaac tcacagacac agtttaaaac
    23881 aataatttta aactgtgtca tcttttatac ctataattta taaattagac cactaaaagt
    23941 atttaataca aaataacaaa tacatcaaac aataaaaaac aataaaaaaa gactatgcta
    24001 aaaacatagt ctttactgga gctggtgata ggaatcgaac ctacaacctg ctgattacaa
    24061 gtcagctgct ctaccgttga gccacaccag cacacctatt ttattgtaaa ttagtaaaac
    24121 taatttttaa aagtta
//
LOCUS       DAEQAF010000056        22752 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.058, whole genome shotgun sequence.
ACCESSION   DAEQAF010000056 DAEQAF010000000
VERSION     DAEQAF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22752
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.058"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(294..845)
                     /locus_tag="KRN00_002331"
     CDS             complement(294..845)
                     /locus_tag="KRN00_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBH1828193.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
     misc_binding    complement(996..1259)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1695..2093)
                     /locus_tag="KRN00_002332"
     CDS             complement(1695..2093)
                     /locus_tag="KRN00_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828194.1"
                     /translation="MNKKKKLIGIAISFLLIISIINPLQVEAEAIIESSVYISSIKEN
                     YTYDNTKFKTIKSKSRHKSRKYNKSKVKLKKRSIRTKKYGYQTINKYKRQNARRHNIL
                     TKLILSIIVIFLIIVLVVLIFIKRKKKKFY"
     gene            complement(2449..2934)
                     /locus_tag="KRN00_002333"
     CDS             complement(2449..2934)
                     /locus_tag="KRN00_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1828195.1"
                     /translation="MISELMLKNFRKSSINFKTKIKLNLREKPDINSLKLKSIPEGKI
                     VKLKCVDGIWAEVESNYDKGWLLYKYLERLSNAKNNSNDTIKNRKKNYIGNIRTNGLS
                     LELRNDRTLESKVITTIPDGFKVEVCYSVGKWARVNINKNEKRYSGYVYNQYIEEHLS
                     L"
     regulatory      complement(3017..3110)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(3466..3849)
                     /locus_tag="KRN00_002334"
                     /pseudo
     CDS             complement(3466..3849)
                     /locus_tag="KRN00_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     regulatory      4075..4172
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            4227..4403
                     /locus_tag="KRN00_002335"
     CDS             4227..4403
                     /locus_tag="KRN00_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828196.1"
                     /translation="MFGNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            4629..4829
                     /locus_tag="KRN00_002336"
     CDS             4629..4829
                     /locus_tag="KRN00_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1828197.1"
                     /translation="MNNGIVKWFNNEKGFGFISMEGRDDVFAHFSAIQTSGFKSLEEG
                     QQVSFDIVKGARGPQAENITIL"
     gene            complement(4993..5205)
                     /locus_tag="KRN00_002337"
     CDS             complement(4993..5205)
                     /locus_tag="KRN00_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828198.1"
                     /translation="MVCKIFITLKTILPKTQIIVTTHSPHILQIDSKEEMIVLDMAES
                     DNVYKKELKLGEYGVLGWTNEGLYLH"
     gene            5514..5696
                     /locus_tag="KRN00_002338"
     CDS             5514..5696
                     /locus_tag="KRN00_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBH1828199.1"
                     /translation="MFKFYNNATLMFLSGTNIKTISERLGHADIKITMNSYSQFLEEM
                     DREAFENLSKILFIIF"
     gene            5767..6612
                     /locus_tag="KRN00_002339"
     CDS             5767..6612
                     /locus_tag="KRN00_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1828200.1"
                     /translation="MNIIKSITLLLTLLIVILMTGCSPRESASEVAKKYIDKMNSGDY
                     ETAYSLLSKDSKKKISIENLEEFQNILVSTKRIISYKIGKEKIIKKYKHDGKEYKNVV
                     KLEETFNIKNLLYKKDDSLKVNRYFVVENNKYKLLLYESFKKEFGINSMDLAQLKLND
                     FGLKYFKEVDLILKKAIAINPTDSKLYYAQACNYMNFDGFPGYSDTTYNALDSINKSL
                     KYLDKNDSDYKKNASNIYNLKGVILMFHKRFDEAQQYLNKALYFNKDNEDPKYNLNTI
                     KKHLN"
     gene            complement(6836..7000)
                     /locus_tag="KRN00_002340"
     CDS             complement(6836..7000)
                     /locus_tag="KRN00_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828201.1"
                     /translation="MFGKPKESVRFLDFNDVAEKFGEKKAVAIFDAIAGKKSKEHIIK
                     DIEKLVKNEV"
     gene            complement(7542..7874)
                     /locus_tag="KRN00_002341"
     CDS             complement(7542..7874)
                     /locus_tag="KRN00_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBH1828202.1"
                     /translation="MNTREMKEYRGFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
     gene            complement(8118..8759)
                     /locus_tag="KRN00_002342"
     CDS             complement(8118..8759)
                     /locus_tag="KRN00_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBH1828203.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNCLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            complement(8740..9033)
                     /locus_tag="KRN00_002343"
     CDS             complement(8740..9033)
                     /locus_tag="KRN00_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1828204.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            9426..9485
                     /locus_tag="KRN00_002344"
     CDS             9426..9485
                     /locus_tag="KRN00_002344"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBH1828205.1"
                     /translation="MTEYIYYYNNKRIKKINLA"
     gene            complement(10001..10753)
                     /locus_tag="KRN00_002345"
     CDS             complement(10001..10753)
                     /locus_tag="KRN00_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH1828206.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(10812..12467)
                     /locus_tag="KRN00_002346"
     CDS             complement(10812..12467)
                     /locus_tag="KRN00_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1828207.1"
                     /translation="MEYFSESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     YQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKQCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIDIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWDVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            complement(13740..14819)
                     /locus_tag="KRN00_002347"
     CDS             complement(13740..14819)
                     /locus_tag="KRN00_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1828208.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQQFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAVAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLSELKNTTIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCILLEEIAPKLAK"
     gene            complement(14903..15559)
                     /locus_tag="KRN00_002348"
     CDS             complement(14903..15559)
                     /locus_tag="KRN00_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1828209.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDIDVFQGDFPTLRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            15881..16087
                     /locus_tag="KRN00_002349"
     CDS             15881..16087
                     /locus_tag="KRN00_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828210.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            complement(16240..16668)
                     /locus_tag="KRN00_002350"
     CDS             complement(16240..16668)
                     /locus_tag="KRN00_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBH1828211.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGYMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(17144..18082)
                     /locus_tag="KRN00_002351"
     CDS             complement(17144..18082)
                     /locus_tag="KRN00_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH1828212.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNGKR"
     gene            complement(18596..19408)
                     /locus_tag="KRN00_002352"
     CDS             complement(18596..19408)
                     /locus_tag="KRN00_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1828213.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            complement(19431..20063)
                     /locus_tag="KRN00_002353"
     CDS             complement(19431..20063)
                     /locus_tag="KRN00_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1828214.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFALIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFRQL"
     gene            complement(20407..22062)
                     /gene="ilvD"
                     /locus_tag="KRN00_002354"
     CDS             complement(20407..22062)
                     /gene="ilvD"
                     /locus_tag="KRN00_002354"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBH1828215.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEV
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELETLAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRMAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIGNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGIVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            complement(22386..22685)
                     /locus_tag="KRN00_002355"
     CDS             complement(22386..22685)
                     /locus_tag="KRN00_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828216.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
BASE COUNT         7747 a         3700 c         2400 g         8905 t
ORIGIN      
        1 gtattcaaaa aatgagaaat cagaggagat taatataaaa atttatcttg aaaagtcaat
       61 taaatatatt ttatatttaa taactacaaa tgagatacat ataagaatat tatataggta
      121 tgataattta tctgttaaat taagtgtaat tggtactata taaatatttt attaaaaata
      181 aatatataat accaaatctt taaacaacat aagaataaaa tagttataat ctactttatt
      241 cttatgttat ttagttatta taatgcttta taaagtaaaa tattatttcg tgtttaagct
      301 tgataactaa ctcttcttat tgatagacta acaatcttga ataaaaatat tcctgcaact
      361 agatttatta aaacagctgg taatactact gctaagaata aagctgtaaa tgaagcccct
      421 ggaagaccaa ctatagcttg agctgctaat aaaaagatag ttccacttac aagagttcct
      481 attggcatta ttattgcaac tactacagta tcttgtgttt tcttagctaa tttttttata
      541 aaaggcatat tataactaat attcattaat aaaaatacta tatttgctgt aagagtttta
      601 tctattacat taggaatttg acctcccgga aaacttgatg taagtgctgt aaatattcct
      661 gttactatac ccgctatcaa acaagtttta taatcatctc tatttaaaac caatattaca
      721 aataacattg ctagtggtac atctggcttc attggtaatc ctatagctgg tgtgatttga
      781 tgtattaata atcccatcgc taaaagtatt gcatttaaag ttaatttttt tgtatttgtt
      841 ttcatttttt gtacttcctc ctattttttt aattttcaat ttattttttt gccaacctac
      901 tatatcatca tctttagctt ttgaaattca taacatcttt ctcaccacct tctatctttt
      961 aaattttcag taaaataaaa aactccgtcc taaactaata ggacggagat tatccgcgtt
     1021 gccacctaaa ttatataaaa attaatataa aattcaattt tcatacatct cattatcagg
     1081 tacttacata ccttattcgc tataacgtgc gactgacgat aaagtctact ctcaaaacta
     1141 tgatttcaat ttattcctct aagggccatt catcaaattt tttcttgcta agattccacc
     1201 atcctcagct ctctatactg aacctaaatt taactactct tccttgtcat aggatttaat
     1261 ttattgtatt gaattttgtt gttaaaataa tgatattctt ttttctaaaa aatgtcaata
     1321 cctttttata aaaaatatat tttgtaatct attttttata aaaaaagtaa attatactat
     1381 acatttcttt tcatatacaa aattctatga ataattactt taatggtcta atagtctgct
     1441 ctttggctct aattcttctt atattaattt tgtgaataac tgttaatgta attttatatt
     1501 ttgattcatg aggaattaaa ttcttcaaag ttaattaagt acctttatca ataaatttac
     1561 ttaattaacc atcatttaat actcattcct gtatttatat gcctcctttg aaacagaata
     1621 ttactccatt ttaattacat catattatta aatagatacc aatgattaaa aaaatgatat
     1681 tcttttaatt atttttagta aaattttttc ttctttcttt taataaatat tagcactact
     1741 aaaactataa tcaaaaatat gactattatg gacaatatta attttgttag gatattatgt
     1801 cttcttgcgt tttgtctttt atatttattt atagtttgat atccatactt tttagttctt
     1861 atacttcgtt ttttcaactt tactttactt ttattatatt tcctactttt atgtctactt
     1921 ttagatttaa tagttttaaa tttagtatta tcatatgtat aattctcttt tattgaagaa
     1981 atgtatacac tagactcaat aatagcttct gcttctactt gtaatggatt tataatgctg
     2041 attataagta gaaaagatat agctatccca atcaattttt tcttcttatt catattttcc
     2101 ccctcataaa aatttttaac tagttcatta taatatatat ataactaaaa attacaaatt
     2161 ttttcaagtt tcttatatat cttattatct ttaatattat ttttattatc ataactttta
     2221 ctttttttaa gatttttcaa agtagtatta atttatgata cttggtgtat aaagtataag
     2281 ttaaatctac tttcaattaa atttaccatt tataattact ttataataaa aataaattag
     2341 ttaatttatt ctctttagtt ctgttataat gtttctacaa aaaagaatcc cattaatggg
     2401 attctttttt gtgatttatt aatatattta aagcttgcta gtatcgtatt ataaacttaa
     2461 atgctcttct atgtattgat tatatacata tccagaatat cgtttttcat ttttattgat
     2521 attaactctt gcccattttc caacgctata acatacttca actttaaaac catcagggat
     2581 tgtagttata actttagatt ctaatgttct atcatttcta agttctaaac ttaatccatt
     2641 tgttcttata tttcctatgt aattcttttt tctatttttt attgtatcat tactattgtt
     2701 tttagcatta cttaatcttt ctaaatattt ataaagtaac caacctttgt cataattact
     2761 ctcaacttct gcccatattc catctacaca ctttaactta acaattttac cttctggtat
     2821 actttttaat ttcaaactat ttatgtctgg tttttctctt aaattcaatt taattttagt
     2881 cttaaaattg atgctagatt tgcgaaaatt ttttaacatt aattcagata tcatcttaag
     2941 ccctcctctt gccaaatatt aagttattaa aatatataac tctaaaaata cttttaacaa
     3001 aaagaattat tatctttttg gcaactggct gacatgacct ttattacata aagattttag
     3061 tccctatagt tttgcgtcat tagatttatc taatattgcc tatatctgaa taataacata
     3121 atttgaacaa ttaaaaaata atattacctc aaattttata ttatttaaat ataaattaaa
     3181 tttttaatta ataataatca aaaaatatct ttatatttat tcaattactg ttctttatag
     3241 tcaatataaa agacagtaat ttatctatag tgttacttat attttatata tatggctatt
     3301 tttcaacatt ttacaatata tataacattt atttttttaa cttttgtcag taaaatgtca
     3361 gcaaaacact ttatccacaa tttttatata agttttccac agcttatccc cagtattatc
     3421 cacataaaaa aggtagctct tacattatta gctacctttt atttactaat cttcatattt
     3481 ccagcttttt atccaacttc ctatttctat tattttttct tcagttattt cttctccatc
     3541 atgtaatttt gaaattaatt ctgataaagg attgttatgt aaacctctaa aaactctttt
     3601 tccctctatt ttgagatatt ctctctcttt tattaatact gtatagtgta catgcctccc
     3661 aattctctat gatattaaaa aacctttttt ggttaatcta gctaaaagta taattgtagt
     3721 tgtatgcttc caaccatatg ttttttctat ttcatctgca acatcttttg atattacagt
     3781 tttataacca gtatgccata tgcatttcat aatttttaat tctgtatctg gtaatttttt
     3841 atttagcata atatattcct tctttcaatt tatgtcactt cttcaaattt atctagctta
     3901 aattataata ggagcttttt agaacaaaaa ctatatttaa tttttaccag gtactctacg
     3961 tgtttagtct gtttttaagt gtaaaataat gttcatatct ataaatttat ttaactttca
     4021 aacaatcctg ttgaataata actaattcta ttgtattatt ttagttgtag aataaaacta
     4081 aatcggcaaa actagagaaa tttagtgacg caaagctata gggactaaga cttatataaa
     4141 tatcttatga gttatgtcag ccagttgcca aagagatagt gttctttttg tttttatgaa
     4201 agttttttag ggggataata atttatatgt ttggaaataa aatggataaa tgtacacatg
     4261 tattgactgc ttatattagc agttcgtatg attattgtaa ttttttagat acacagttag
     4321 atgattttat attagagtac ggagaaaatg tagtagagtc ttgtttacac caagtaatgg
     4381 tattggtaag taagtataat tagatagaca ttgatttcta gaaaaccctt tttagtttta
     4441 tctacattta tattaatata tagcaatgta aaacgtttaa atatattttt aatattaaga
     4501 ataattaaaa tgttaactaa aaaatataat taagtagaca tttctattaa tctatgatac
     4561 aatagtattt gtggtaatac acaattaaat caagtatatc ttgatatagg ttaataggag
     4621 tatttttaat gaataatgga atagtgaaat ggtttaataa tgaaaaagga ttcggtttta
     4681 tatcaatgga aggtagagat gatgtgtttg ctcatttctc agctatacaa acttcaggat
     4741 ttaaatcatt agaagaaggt caacaagtaa gctttgatat agttaaaggt gctagaggtc
     4801 ctcaagcaga aaatataact atattataat atatagattt ttcgggaaag actcttttta
     4861 gagtcttttt ttattgttaa tatatgtaag ataatcattg gtgaagtaaa taaggtatat
     4921 tgagtaatgt tcttgatagt ttatatgcta atgaatttca aaaaaataag cactcctata
     4981 aaaagagtgc tcttaatgta aatataaacc ttcattggtc cagcctaata ccccgtattc
     5041 tccaagtttt aactcttttt tatatacatt atcactttca gccatatcta acacaatcat
     5101 ttcttcttta gaatcaattt gtaaaatatg aggactgtgt gttgtgacaa ttatttgtgt
     5161 ttttgggaga attgttttta atgtaataaa aattttacat accacatagt tgatataaaa
     5221 cttgcagagc aaagagactg aaattgttac gttttatact ttacatacca catagttgat
     5281 ataaaacccc aaaataaact tagcatctcc aatgtttaca catatacaat gctcttaaaa
     5341 ttgcagtgaa tgtgcaatag tgcaattgat aatacttatt atatattctc aatgccttat
     5401 atttcaactg ctaaacctca atttgtcaca aatatcgctc actgcaaaat ttctatattt
     5461 ttattatatc atagcatata attaatattt tcaattaatt tttacattta attatgttta
     5521 aattctataa taatgcaact ttaatgtttc tttctggaac taatataaaa actatttcag
     5581 aaagattagg tcatgcagat ataaaaataa ctatgaatag ctactctcag tttttagaag
     5641 agatggacag agaagcattt gaaaatttga gcaaaatact atttattata ttttaaagaa
     5701 gatgacttat tcaatatttg atgctagaat ataattaata aaaatttaat tataggtgat
     5761 tgtattatga atattattaa aagcataact ttactcttaa cattattaat tgtgatatta
     5821 atgacaggct gttccccaag agaaagtgct agtgaagttg caaaaaaata tattgataag
     5881 atgaactctg gtgactatga aacagcatat agtttattaa gtaaagatag taaaaaaaaa
     5941 attagtatag aaaatcttga agaatttcaa aatattttag ttagtacaaa aagaataatt
     6001 agttataaaa taggtaaaga aaaaatcata aaaaaatata aacatgatgg aaaagaatat
     6061 aaaaatgttg ttaaattaga agaaactttt aatataaaaa accttcttta taaaaaagat
     6121 gattctctaa aagtaaatag atattttgta gttgaaaata acaaatacaa gctattattg
     6181 tatgaaagtt tcaaaaaaga atttggtatt aatagtatgg accttgctca acttaagctt
     6241 aatgattttg gactaaaata ctttaaagaa gttgacctta tactaaaaaa agctattgct
     6301 attaatccta ctgattcaaa gctttattat gcccaagcat gtaattatat gaattttgat
     6361 ggatttcctg gttattcaga tacaacatat aatgctttag attcaattaa taaatcttta
     6421 aagtatttag ataaaaatga ttctgactac aaaaaaaatg caagtaatat atataactta
     6481 aaaggagtta ttcttatgtt tcacaaaaga tttgatgaag cacaacaata tttaaataaa
     6541 gccttatact ttaacaaaga taatgaagac ccaaaatata atctaaatac aataaaaaaa
     6601 catctaaact agatatttaa tttttgaatt tataaaatat ttttttatgt ataattcagc
     6661 actgaatcat aatctctact aaactaatta caagtttaaa ttataaagac ttatttctat
     6721 ataaatatta ctctataaca ataagtttct tatttaaatt ttaaaatatt atctaaaaat
     6781 cataaaaaag aaggtataaa gagctaccct caagctcaat ataccttata aatatctaaa
     6841 cttcattttt tactaatttt tctatatctt tgataatatg ttctttagat ttttttccag
     6901 ctatggcatc aaaaattgca acagcctttt tctctccaaa cttttctgct acatcattaa
     6961 agtctaaaaa tctaacactt tcttttggtt taccaaacat ataacacctc tcatacattt
     7021 ttatatattt attataactt ctatagactt atttttcacc aataaacgtt agacaaatta
     7081 gtccctttat ttttttaaac tagctttacc ttcaaaattc ttaacaaaaa cagtttattc
     7141 tactctataa ataaaaatag acaatttaat ttgtaggaaa ctgataatag aatacagtaa
     7201 ataaaacttt gtttaatcta tctgaaaaag ttatctatta aaactgctat gaatttataa
     7261 agaatattct agttcataaa aatacaaata tgtaaatata atcaccttaa tattcaattt
     7321 atttaaaata aaaaatgtat aaaagattta ataatgacaa tatactattc tcaatacaat
     7381 atatgatgta aataatttaa aactactata ttatttaaaa atttatattt atatatgcaa
     7441 ttctaaaaac ttaataagaa gtgaacttag aaaataaagc ttaatttcaa agacttaaat
     7501 agactattat tattagtcta aataaactac gtctatcaaa attatatatt aaattcttct
     7561 aaaattttta ttgcaaatct tgcgtttgga tatgtaatag acccgccacc aattacacct
     7621 atttttatag cttctataat ttcatcttta cttgctccag aattaataca accctcaata
     7681 tgataacaaa tacactcatc acatcggctt aaaattgaaa tagctagtcc cattaattcc
     7741 ttattttttt tgcttatagc cccttctgaa taagtcttat catcaagact tccaaatact
     7801 ctaaaaaact catctgtttc gcttaatttt ttattgtaaa atcccctata ttctttcatt
     7861 tctctagtat tcatcttcta cctcctatgt ttttcttata agaatatcac actgtactta
     7921 tattttcaat attaaataca aattttcatt ttatgttcat tagcctaatt tatattattt
     7981 tttgaaatct caataagtta tcatataagt aagatttttt cagaactaaa atagaaatct
     8041 tagtaatttc tttattatct atctcagttc tgaaatatat tattcttatc caaacattat
     8101 tatagtgatt aattatatta gttattttta cctgaaattt tatacatcaa ataagaatat
     8161 ataaatggta gtattacaat tacaaagatt acaaagatat tataaaaagg aatattaata
     8221 aatgcattaa taattaataa tattccacca ataagccaaa tccatccagc taaatggtgt
     8281 gtcttattcc aattatcttc atcattcaga gtccatggca aaattattcc tactgagtaa
     8341 tttcgtttac atttaggaag acagtttcca aataaaataa ctattattcc taaaattaat
     8401 cctgtataaa aattagactc caaactaact cctgttgaat ataaaaccat cattatttgt
     8461 ataattactg aaagtatagc aactccccat tttgataaat tttgtataac atttgaaaaa
     8521 ttagctttct taggctcatt ctcaagtcta aaccatgtat acaaatggat acatagcatt
     8581 aacaatggta caccaaaagc tgctataacc tttggagcat aattatctgg atttccataa
     8641 ttatcaaaat gaattgcaac ttcatttggt aatctattat aaaaatatat tgatacaata
     8701 aatggtataa aacatattaa agtagataaa ataaattgtt tatttatcgc ttttttcatt
     8761 atctttttct cccttctcca taaattgtga aaaccaaagc atgacctctt cgaaaactga
     8821 aatatttatt tcgtagaaaa taaagttctt atactttgtt tcaaatatga gtcctgcctt
     8881 ttttagttga gatagatgat aagaaattgt agcattcgtc atattaaatt tttcactaat
     8941 ttctcctgct gacattttat tctccctcaa cataaccaat atttctcttc ttatagggtc
     9001 tgaaagagct ttgaatgttt ctggaaaccc caacaccatc acctcgctat ttagaatttc
     9061 atctaaatag aatataacat agcatccatt ttatttcaat agctatttag aaatttttct
     9121 aaatagttat ttctaaatat ttattgaaaa ttttcatatt aagattctca atttacttaa
     9181 gtcgctttta tttaatctta ctttatctaa tttttttaac ttaacaaaag tgtattgcac
     9241 cataattgtt aaagcaaaaa cctaatgatt gaggtactta tatatataac aatactttta
     9301 attttaaatt aaaagtagct aaacccaatt taaaaagtag ttaagtccta tttaaataga
     9361 aaagaatgaa acgagaaata tactgtataa aagtacataa aaacatctac taattagata
     9421 caactataac agaatatatt tattattata ataacaaaag aataaaaaaa attaatttag
     9481 cataaccttg ttaaatatag atttgaatat gaatttaaag ttatgtaaaa ttaaaaatac
     9541 aggaatgaaa attccattcc tgtataaaat ctaacttttg agtctcagta caatcttatt
     9601 ttgagacaat cttttttgtt ttatattttc ttatatttaa aatataacgc atatcttatg
     9661 caacatattc atatttttct ttatattctt tcatcgcatc attccaagcg tcttgtactg
     9721 ttacacctct tttattagca attttttgtg ccagttcaat tatcttcata gctcttcttg
     9781 atatgttcat aaacattcct cctacaaatt accatatatt tcatatatat aaatcaaggt
     9841 tatattttta tgatatataa tccttctatt gtaagattac agtttatatg tgtattatat
     9901 atgaactata ttagaagata attagaattt ttataaagct atatgattag attaaatata
     9961 aaagctttac aattacttat aaatttaaaa agtctataaa ctaaactaat gtttgatata
    10021 ccaattttac gaccataaat aatgccatta ctaaaaatat tggttttatc atctttgaac
    10081 ctttctttat agcaacttta gcacctacat aagctcccat tatcatcact aatgcaaaca
    10141 ctatagcaat tttataatct acttgaccat ttatcatgaa taataacaat gaagttatat
    10201 tacttgttaa gtttaatatt tttgtatttg cagaagcatg taaaaaatca tatccatata
    10261 tttttataaa tccaaaagtc aaaaaagttc ctgtacctgg accaaaaaaa ccatcataaa
    10321 aacccattat aagagccata agcatcccta gtcttaaatt tttcttatta acagcttcaa
    10381 aattatcttc ttgacctaaa tttttagaaa taaaggtgta aatagccact attaaaatca
    10441 taaccacaac caaaacattt aatatctctt cacttattga taatacacat ctcacaccta
    10501 gaacactacc aataatagta aatggtacta atttttttaa aaggttgtta ttaatttttc
    10561 cagactttgc atatctatag gcactactta tacatcctgc tgatgctgca aatttatttg
    10621 taccaatggc aagatgtact ggcactccaa ttgccataag aacaggcatg cttataagtc
    10681 ctcctcctcc tgctatagaa tctacaaaag cagctaaaaa cccccctata cataaaaaaa
    10741 taactgaaaa cataaaattc ctccatcatt ctctttcaat ttttcttaca atatatatta
    10801 tataatctta tttaatactt attatccagc atattctttc tatattcatt tggagttata
    10861 ctattaaact tcttaaatat ttgtgaaaaa taactactgt tattaaaacc tactttctta
    10921 caaatatcac taatactcat gcttctatct aacagatatt ttttagattc ttctatccta
    10981 agaagattta tatactcagt tattgaaact ttatttcttt cattaaaaat agaactcaaa
    11041 taatttggac ttataaaaaa aacatctgat atactattca aatttatatt ttctttataa
    11101 tattttttta tatattcgtt tatattttca attagatttc ctttatcttt tctccaaaat
    11161 gctctattct tatcaataca ctctttggaa aattcaaaca atacatccca taaatcttca
    11221 tcactgttta caagtgatat ttttttgttg tatttatttc ttaaataaga tataagtttt
    11281 aaatcctcta aatctctaag cactgttcta gacaatacaa atatcatttc ctgaatagta
    11341 tctctaacat cattatatct taatttgttt gtatctatta gattataaac accttctaaa
    11401 ttcatatttt taatttcttt ttcaatataa agttctaatt caaagggata ttcttttgaa
    11461 gaattattga acatatctat cggattaata atatactctt cttctaataa tctactattt
    11521 gcttttttaa gtgcctcttc aagtcttata ttttcttttc tactcttcaa tatctcctca
    11581 tcttttatac taagttgatt ttcaaaaaaa ttcctcttag ctatttcctg aataaattca
    11641 gacatcatta ataaattttc ttttaataca tataatctac ttttaggatt taatggaaat
    11701 tcattgtaaa ttttgtttat gtattttata tcaataccag aactacttga taattcagat
    11761 aaatttttat ctatatcaat agacttatat actataaaat taccacattc tatatatcca
    11821 actatatttt cttctaatac tataggtatc tctaaactgg aaacaccata ctcacaatgg
    11881 tacacttttt caaagttatc attatttatg cttttaacaa gttttttagt acactgtttt
    11941 atatttttac aaatatcgca aaatttattt tctttcttag tctcaaatat ttctttatac
    12001 tttaagtcat atacagatat tctaagcttc aatatattag atatttgatt tgcaagattt
    12061 tcaattatgt ttacattaac taactcctgt atattgtttt cagaaaatac tataggtatt
    12121 tgtctcaaac tcgaaaattt atgaggaaca taagtaatta atattactaa atcaatttta
    12181 ccagtgttta taatttcatg ttctgaatat ggtgggcaat aaactataga tgtttccttt
    12241 atattgacct ttttaccatc aattatttgt attccttctc cctgaatcac atataaaagc
    12301 tgttcttcac ttaaatgaaa atgcttttct tggtagtttc ccggaaaaaa tcttacaatt
    12361 ccagcactaa gtctattgaa ttgtgttttt gatggttcgt gtatccacat aacctctccc
    12421 caatcaaatt tttgtacttc attatttgac tcactaaaat actccataag ctcacctctt
    12481 agtttttgtc taaatatttt ttcttccctt cttatattaa aataatatca tcatcattaa
    12541 ctttcattac tataaaatca tcatactctt ttaatactcc tgtaatttta gttgcactta
    12601 gtttactaca attcagtttt ttaatatatt gataaattct ataattactt ttttattttg
    12661 taaaatcagt gttttcccaa aataattata tctataaatg aaagtatttt tactgcttac
    12721 atcaatatat gttatcataa ttttcctttt tattgcatat ataaataact gtatataaca
    12781 ttgtccaata ctatatagaa atacatctaa gaaagaatat tattaaattg ttccaattag
    12841 tattattttt cttatagaaa taaaaaaact gttggattct tttagaaaaa ttatttttta
    12901 catacctttt ttgcttagat agtctatctt ctcagctatt ttgtatatac actcttctag
    12961 ttcatgattt tattttaata tcttgcttat attgctgaaa taattgaatt cttttatcta
    13021 tcatattgtc tcttatatca caaacatatt gtttcttata tcacaaaaat gaaagcattc
    13081 ttatatcttc aatatataaa cctgcttttt ttaatcttgt aataaatata ggatactcta
    13141 tattctcttc ctagaaataa ctaataccac ttatttttct attatataga aagtaataaa
    13201 tctttttctt aataaaattc aatagtaagt ggaataaaat tttatataaa taagaacatt
    13261 ataaaaatac tttatacaat agtcaataaa agatattagc ttcaaattat gttaaagttg
    13321 tattatttaa agtgaaaaaa caaataaaaa agaaataata gtataagtag aaaaatatac
    13381 ttaaaacaag gcgaagcctc tcttgtatct aaatcaagta gagaattaaa tctaaaaaag
    13441 aaaataaata taaaagatga ctcctgtaca ttacaagaat catcttatgg tttcataatc
    13501 actccatggt ttttaactgt ttgatataaa ggtctcagtt cactcatagc atgaccacct
    13561 tttccgattg ctgaccccgt cacttatgga caaaatgtcc ataagtgata gtcctctctt
    13621 aaaaccctct aaatagatat atctcaagca ccgcattgaa accagttgct ggaaacaaac
    13681 tgaagcgttc tggaatagta aaagaaattg ccaccatatc cacgttactg tcctagttgt
    13741 tactttgcta actttggagc gatttcctct aacaatatgc agtcaaattc tgcctttttg
    13801 ctaagaaatg gcagatggtc tgcatctggt ataaaaaaaa tctgtttgtc tggcgccact
    13861 atttcatcaa aaaatttctt cgctggaaga taggggctat tatagtcatt ttctcccatg
    13921 atgtagtata caggaacctg atagtcaact ccataatttc ttatgtcagc ttcttccact
    13981 aaaaaccgca atacatcacc ttgattgtca atcgcatttg gattgacaat ggttgtattt
    14041 tttaactcgc tcaatgaata atacggggtt gccagtatac tgattatatt gcccaaatcc
    14101 atatttatag aaagcccata cttgctttgg tatgttctta ctgtcataag agccgccaaa
    14161 tagcttggac catattttgc tggcggatat ggtgcaacag cttccagtgc cttgatatct
    14221 ttttgctttc ctgcagcttt caccatttca agtgtctttt catagcccac gcgctcattg
    14281 tccaccatat taacggtctg cgcaatccca atgtacgcgc tgtaatcctc cggataggtt
    14341 tgcacagcca tagttcccag caccgttccc cagctatgac ctataaggat aattttctcc
    14401 ttgttgaact gttgcttcaa atatgctgtc acctcatgga cgtcttgcag aacacgctcc
    14461 gcgctcatgg tctgcaaaac tgctgccgga tcgttcgcaa agtatgtttt gcctacgttt
    14521 cgctgatccc agttcaccac agtaaaatca ttttcccact catactggta cagatgtaaa
    14581 aatggcatca ttgaattacc aggaccccca tgaacccaaa ggatgatggg gttgtctgcg
    14641 ttttgtcccc ggatatataa cgcctgctgt atgccgccga tctccaccat ttccatgcgg
    14701 tcgattccag gagcttctat tttatggctt gtacgtataa tcgtgggggc tatcagacgc
    14761 aaaccggcaa acgccagaac aaaaacagca actagtatgc aaagtgtgat taatatcatt
    14821 ttaagtacct tctttcatga atttttttag ccatagatat ctcctctaac attaaaaaaa
    14881 gtatgttgct attttagttt tgttactcta cctgtcccat tggtttcctt tcataaaaaa
    14941 tattaattga ttctataatc tcatcttcca gaatatcaac tcctatttgt ctcataagaa
    15001 actgtaagaa ttgaaaccgt ttacgaagtg taggaaagtc cccctgaaat acatctatat
    15061 cacaccaaaa gttaaagagc agcaaaatta cctctgcgca ttcatctggg aactctgtga
    15121 tgatgcttct atcctctatg ccttctcgta aaacatttgc taatattggt gctagttttt
    15181 tcaaattatc ctgtgtaaat gccagtatga tatgcggact ttctatcgcg cttgtaatca
    15241 tgttactaga ttcttttatc acctcatccg ttaaatgccg cctaactaaa cttctaagct
    15301 tctcttttgc tgtaagtcca tgcatttcac cgagccattg atttactgtt tctattatct
    15361 gttcaaagcg cctttccatg accacattaa aaatatcttc ttttgaactg aagtgatgaa
    15421 aaattccgcc ctttgacatt cccgaagcat caacaatatt ttgcatactt gttttgtcat
    15481 atcctttttc agcaaacaac tttgcagaaa tggtaatgat attttcaata gcttgctttg
    15541 gattgttctt tctagtcatt atataactcc ttcttattaa aaaccgactg ttggttttta
    15601 ttatataagc tattcctgct tctgtcaagt aacattgtgt ttatggcaaa acaataaggt
    15661 ttggtggtta gacaggtatt aattagacta atgcgacttt cccctagatg gaacccttgg
    15721 taaatttgca atctttaccg gctttgatta tatctgtaag caaggcaggt atggccacac
    15781 ctgccctgtt tgcccctcgg atattcattc ctatccctcc tctccttagc cattacacca
    15841 aaacgccgct cattgtctcc aatggcggcg ttttaaagat atgatttctc atgctgctga
    15901 aatatgcaaa aaatataaga tgccctttat tatttttcct acaatagaaa agaaaagtat
    15961 tgaagaatgg gttaatattg gagcaaatat gctttgtttg gcacaagata ctacctttat
    16021 cacttatgtt atcaatcaat tattatcttt ttataatgag attgtaccaa ttcaaaaaca
    16081 acattaaatt ataaatctaa ttttatatta aaagagacta atattttatc tatctttatt
    16141 aaggatattt tcttatgtat cataatatta gtctctctta ttattatata ctgctatcat
    16201 cattagttgc tatttatact atttttataa tatacaaatt tattcagcta acgttttgcc
    16261 taattctata cactcatctt ttgcttcttc atttgggtct tccattgctg taattccttc
    16321 tccaccaata attgtagcac cagcattttg catacgttct tcccagtctc tcatccattc
    16381 acaatttccc catccatatg aaccaaataa tccaatctgt ttacctgata ccatagattc
    16441 taattctgaa acaaatggct ccatataccc ctcttctagt tgctctgctc ccatagatgg
    16501 gcaacctaat gcaaatttat cttcttcttt taaatcactt ggtttcagta agctcacatc
    16561 taaaacttct ggtgtcttac cttttaactt cacaccttca gccacaaaat ttgccatttt
    16621 ttcagtattt cctgttccac tccaataaac aatatatatt ttactcattt ttacctcctg
    16681 tagtattttt taattaatca atagttagtt atagctaact aacatctaaa aaacaaaaga
    16741 tttctttatc tgaaatctct ttatttttct aaatatagaa tatcatagtt gattttgaaa
    16801 ttcaatactt attgataata tttatcattt atattttata ttcattttat aatatcaaaa
    16861 cactgtatcg tatttctaat ctttcataga aaaatttcta acttatagta cttttgcatc
    16921 tcttataaat cttttatata tataagtaca tagaaaaaca caccttttcc agatgtgcta
    16981 tctataatat cgtatattta tttttcaatt ctaactagct aatatgttta taaattttat
    17041 cacttaatac ctttatacat tgatgtaaaa tcttacacct aagtaatttt tattatttgt
    17101 ctcgactcta tataatatag ctattttatc atcaaatcaa aaattatctt ttgccattat
    17161 tcttgtattt ataaagattt aaatataagt atccatttcc ttgttccgtt ctaggtattc
    17221 caagcgctct cgtacatttt attaattgtg catacagttc agcttcatct aaatctcttt
    17281 caaactcctc tcttgcccat tctttaatta gtgctaatga gcctgatacg tatggtgcac
    17341 tcatactagt accactcata atagcaagtt tattatccat ataagtcgat ataatatttc
    17401 ttcctggagc caccaaatct attgtagtat ttgaattact aaacttttca accaaatagt
    17461 tttcatttat tgcacctact tctattacct cagcataact ggctggataa ctatactcac
    17521 ttgtactaga atcaccatct ccattattac ctgctgcaca cactacagaa atattatttt
    17581 ttactgcttg catgacagca ttttttaaat tcttatcatc tttgtttcca ccaagagaca
    17641 tagatataat atcaaccttg ttatttacag caaagttaat agcattaatt atactttgat
    17701 atgttccagt accatcttta tttaatgctt ttgctattaa taatttacaa tctggagcta
    17761 ctcccataac ttcattatta tagttagatg cagctataat acccgccaca tgagttccat
    17821 gaccattaaa atcctcatat atatttttat ttccattact gtcatcacta aaatttgcac
    17881 caccaattat ttttcctttt aaaagaggat gagatatatc acaacctgta tctattatac
    17941 caactacaat atttttacca gtataacctt catcccacat tcccctagca ttcatttgtt
    18001 ttattccata tgggaattta ttttttgcac ctcttagatt ttcatttatt tcatatggaa
    18061 ttagtttcat tcttttattc atcatatatc ctcctaaaaa ttttattgct tataaaaatc
    18121 atgaatttta ttttataata ggtttataaa tcaaattaaa acctatatct acttatttat
    18181 atttatgata tattttttat ttttaggagt catattttat tgtatataaa ataatattta
    18241 gataactata ttaaaaaata catgtttgct tatatacaaa acttactaaa atatcttcaa
    18301 tatttttgta tacaaacatt atatttttta tataaaaatc tcataaaaat tttgattata
    18361 ttttcataag ttaacaaatg tgggtataat atgaatttac aaaattcctc tgtttgtata
    18421 agtgctttac caatacacta atatataatc acattgaagc tatatttgta tttatagtag
    18481 ataatgtatc aaaaattggt tatgaatagt aaaaatacca gttaagcata ttttcatgtt
    18541 tctattttta acattaaatt tccaatcttc atatgtatat ttttaacaaa ggtgtttact
    18601 tatttaaaaa ctctaaaact ctttcattaa aatcctgtgc ttcttcatat gtagcgtgtc
    18661 ccaatccctc atagataaat atttcgcttt ttttaatctt ttctgctaaa tgaaaagaag
    18721 cattatttcc aacaatttta tcattagcac ctcctataat taaggttgga catgttattt
    18781 tatttaattc ggaaaaggca ttatgttcta tgcaagaggt cgcttgaata ataaatcgtt
    18841 taaaatcctt tggtttacct acttttccta aaaaaggaat aaataattgg tattttttta
    18901 aatatctttc agaataggat ttctttgctg tgtcaatcat taaatcattg taattctgct
    18961 tcttcgccat atcaatccaa ctacaaataa cattttggat agtatcattt tgctttgaag
    19021 aagtaactgc caacacaagt ttctcaacta actcaggata atcaattgcc agatattgag
    19081 ctatcattcc accttgagaa acacccatta cttctgcttt cataattcca agttttttca
    19141 ttatatctgc ttggtcttta gccatatccc ttgtggaata tttttctgta atttgatttt
    19201 ttctactaaa tacataaacc ttataatctt ttgcaaattg cttatatcta aaagcaaaag
    19261 caatcgcctg tatttttcca tgtaaaggaa ataaaccatc tcctaatcct ggtaaaataa
    19321 ttagtgtctt cttaccacta ccaaattcaa tataattcac tgtattactt cctatcatca
    19381 tttgacaact ttttgcatta taaaacatag tctattcctc gcttttccta ttataattgt
    19441 ctaaataaat ctttaaattt ttgaatacca tactcatcaa ttagaggaat atccattttt
    19501 tttaacatga ataataaaaa atccaaccta ttacatactt cactgtattc acgtttaaat
    19561 aatacagggt caagtaaaat atcaatacta aaaacgagca tttcagctaa ttcctctgga
    19621 tattcacaag aaaattcttt attttcaaca ccttgtttaa ttatcttagc aatattgggt
    19681 gcaactacat tgttgagatt acgaacttcc tctattaaag cgaatgggat tttttctaac
    19741 cagctacaat gtaccatttt tctacgtgtg taatcattcg cactatgaac aaccaattct
    19801 attatttttt catttgctgt aagggtgtca tcagcaacaa gatgctctaa aaaattattc
    19861 atttgtgagt aaagttcttt tgtgacactt ctcagtatat cttctttagt tttaaagtga
    19921 tgatacattg cacctctaga tagaccagat aaattgataa tatcttgtgt agatgttgaa
    19981 tcatatcctt tagacgaaaa tagtgaaaat gctgattgga taattttttc tttactattt
    20041 ttactttttt cttctctatt catatttccc tcctaaaaac agactgtctg tttgtttttt
    20101 attatacatt ttaatattta ttatgtcaag aattaactga ctttcaattt cttcatagtt
    20161 cagatggaac gaaaagcatt ccacatcaaa cttttaaaaa gttgtattac ctcaacaagg
    20221 tctaaaagat acatctctat gctgtactcg tattccttat aatagagatg tattgttttc
    20281 aaagataatc aagattttgc tgtgtttttc atacaaaata aaaaggatac ctcattagtg
    20341 ctataacacc taagatatcc aattaatatt ttcttaactt tttctaattt acataaatat
    20401 agtctactat tttaaaactg ctcctgtatt tgctgatgtt accaatttag catatctact
    20461 taagtatcca tgctttattt tcggttctaa aggtttaaat tttaattttc tattttctat
    20521 ttcaacttca tctactttta actctaattt tttgtctggt atgtttatag aaattatatc
    20581 tccttcttca actattccga ttaaaccacc ttccatagct tctggagaaa tatggcctat
    20641 ggatgctcct ctagttgccc ctgaaaaacg accatcagta agaagtgcta catgcttatc
    20701 aagtcccatt cctgcaactg ctgatgtagg agatagcatt tctttcattc ctggaccacc
    20761 ctttggacct tcatatctta taactataac atcacctttg tttatttttt taccaaaaat
    20821 agcatttaca gcttcttctt ctgaattaaa aactcttgct ggtccttcat gaactaacat
    20881 ttcttctgca actgctgact tttttacaac agctccattt agagcaagat ttcctttcaa
    20941 tattgcaagc ccaccttggt tactatatgg attctttaat gtatgtatta cttcttcatt
    21001 ttctatttca caatttccta tattttcccc tatagtcttg cctgttacgg ttttgcaatc
    21061 taaatttatt ccatttatct ttgaaagttc gttcattata gctggtattc ctcctgccat
    21121 atgtaaatct tcaatatgat gttttccact tggacttaat tttgttaaac aaggagtttt
    21181 ttcacttatt tcatcaaaaa aatctaagtt aagctctatt cctgattcat aagctattgc
    21241 aggtaagtga agtactgtat ttgtagaacc agccattgcc atatcaacag ctatagcatt
    21301 tttaaaagca tctattgtta aaatatctct aggttttatg tcgttcttaa gtaactccat
    21361 aacatacata cctgcatatt ttgccatcct ttttctttct ccagaatgtg acgcagcagt
    21421 accattatat ggtataccca tgcctaaagc ttctgttaaa caattcatgc tatttgctgt
    21481 gaaaagacca gaacatgaac cacatccagg acaagagttc atggctaacg tttctaattc
    21541 ttcttcactt actgttccat ctttacatgc tccaacaccc tccattgcag agttaaaatc
    21601 atatactttt ccattttttt tacctggaag cataggccct ccactcacaa caatacttgg
    21661 tatattaagt cttgcagcag ccattaacat acctggcact atcttgtcac aattaggtat
    21721 aagtaccaaa gcatcaaaac catgtgccat agccataact tctattgaat ctgctattaa
    21781 ttctcttgaa gccagggaat aattcattcc aacatgcccc atagctatac catcacatac
    21841 ccctatagca ggaaattcta atggcaaacc accactcatt cttactccat tttttgcagc
    21901 ttctgctatt tcatcaagat gcagatgacc aggaatcacc tcattttgtg catttactat
    21961 acctattaat ggtctttcaa tttcttcttt agtaagaccc attccataca ttaacgctct
    22021 ctttggagct ccttctattc ctttttttat atcacttctc ataatattac ctctttctta
    22081 cttttttaaa ttttcataat attattataa tatatttttc tattaattaa ttacgaaaat
    22141 tgtaaaaaaa tattagcata tactaatgaa aatttattac gattttttat caatatctta
    22201 cacaatcgta ttatataata ttatcttttc aatatatttt ataaactaat atattttaca
    22261 aattgttgag taatatttta tgatataaat cagaagaggc acttctataa tagaaagtgc
    22321 tcaactatga ataagattaa taatatattt gccttagata tatagacttt tataaatatt
    22381 aaagattaat caaatctgat gtttgaaact ttatcccaat taatcttcct tgaatagtct
    22441 tctggatgtg ataatctaac tatatgagtt gaattatcat agctgtaata aattgtagta
    22501 gtaccatcaa ctggattctt tttgtatcct tgatacacag cactatttgg tactttcttt
    22561 tcaacaaagc tatatgcaga tgaagtatca atagtttcta ttttattagg aaatataaac
    22621 atataaaaag ctactactat aaaaatacat atgcatgtaa tactatacca tttaatccat
    22681 ttcataaaat tcctcctact ttaccaaaat atactattat tatttccata tatttataat
    22741 atttatacat ac
//
LOCUS       DAEQAF010000057        22583 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.059, whole genome shotgun sequence.
ACCESSION   DAEQAF010000057 DAEQAF010000000
VERSION     DAEQAF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22583)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22583)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22583
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.059"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..639
                     /gene="tuf"
                     /locus_tag="KRN00_002356"
     CDS             <1..639
                     /gene="tuf"
                     /locus_tag="KRN00_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH1828217.1"
                     /translation="EWGDKIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTV
                     ATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQR
                     NEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGAC
                     KLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
     gene            1011..1322
                     /gene="rpsJ"
                     /locus_tag="KRN00_002357"
     CDS             1011..1322
                     /gene="rpsJ"
                     /locus_tag="KRN00_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBH1828218.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1414..2043
                     /gene="rplC"
                     /locus_tag="KRN00_002358"
     CDS             1414..2043
                     /gene="rplC"
                     /locus_tag="KRN00_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBH1828219.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFET
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            2073..2696
                     /gene="rplD"
                     /locus_tag="KRN00_002359"
     CDS             2073..2696
                     /gene="rplD"
                     /locus_tag="KRN00_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBH1828220.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2696..2986
                     /gene="rplW"
                     /locus_tag="KRN00_002360"
     CDS             2696..2986
                     /gene="rplW"
                     /locus_tag="KRN00_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBH1828221.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            3016..3846
                     /gene="rplB"
                     /locus_tag="KRN00_002361"
     CDS             3016..3846
                     /gene="rplB"
                     /locus_tag="KRN00_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBH1828222.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3881..4162
                     /gene="rpsS"
                     /locus_tag="KRN00_002362"
     CDS             3881..4162
                     /gene="rpsS"
                     /locus_tag="KRN00_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBH1828223.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            4194..4529
                     /gene="rplV"
                     /locus_tag="KRN00_002363"
     CDS             4194..4529
                     /gene="rplV"
                     /locus_tag="KRN00_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBH1828224.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4552..5367
                     /gene="rpsC"
                     /locus_tag="KRN00_002364"
     CDS             4552..5367
                     /gene="rpsC"
                     /locus_tag="KRN00_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBH1828225.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5403..5834
                     /gene="rplP"
                     /locus_tag="KRN00_002365"
     CDS             5403..5834
                     /gene="rplP"
                     /locus_tag="KRN00_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBH1828226.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5836..6039
                     /gene="rpmC"
                     /locus_tag="KRN00_002366"
     CDS             5836..6039
                     /gene="rpmC"
                     /locus_tag="KRN00_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBH1828227.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            6063..6317
                     /gene="rpsQ"
                     /locus_tag="KRN00_002367"
     CDS             6063..6317
                     /gene="rpsQ"
                     /locus_tag="KRN00_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBH1828228.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            6343..6711
                     /gene="rplN"
                     /locus_tag="KRN00_002368"
     CDS             6343..6711
                     /gene="rplN"
                     /locus_tag="KRN00_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBH1828229.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6735..7040
                     /gene="rplX"
                     /locus_tag="KRN00_002369"
     CDS             6735..7040
                     /gene="rplX"
                     /locus_tag="KRN00_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBH1828230.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            7070..7612
                     /gene="rplE"
                     /locus_tag="KRN00_002370"
     CDS             7070..7612
                     /gene="rplE"
                     /locus_tag="KRN00_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBH1828231.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7630..7815
                     /locus_tag="KRN00_002371"
     CDS             7630..7815
                     /locus_tag="KRN00_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBH1828232.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7848..8246
                     /gene="rpsH"
                     /locus_tag="KRN00_002372"
     CDS             7848..8246
                     /gene="rpsH"
                     /locus_tag="KRN00_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBH1828233.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            8277..8819
                     /gene="rplF"
                     /locus_tag="KRN00_002373"
     CDS             8277..8819
                     /gene="rplF"
                     /locus_tag="KRN00_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBH1828234.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8855..9223
                     /gene="rplR"
                     /locus_tag="KRN00_002374"
     CDS             8855..9223
                     /gene="rplR"
                     /locus_tag="KRN00_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBH1828235.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            9244..9753
                     /gene="rpsE"
                     /locus_tag="KRN00_002375"
     CDS             9244..9753
                     /gene="rpsE"
                     /locus_tag="KRN00_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBH1828236.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9768..9953
                     /gene="rpmD"
                     /locus_tag="KRN00_002376"
     CDS             9768..9953
                     /gene="rpmD"
                     /locus_tag="KRN00_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBH1828237.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9986..10429
                     /gene="rplO"
                     /locus_tag="KRN00_002377"
     CDS             9986..10429
                     /gene="rplO"
                     /locus_tag="KRN00_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBH1828238.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10473..11741
                     /gene="secY"
                     /locus_tag="KRN00_002378"
     CDS             10473..11741
                     /gene="secY"
                     /locus_tag="KRN00_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBH1828239.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSGEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11758..12408
                     /locus_tag="KRN00_002379"
     CDS             11758..12408
                     /locus_tag="KRN00_002379"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBH1828240.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            12409..13155
                     /gene="map"
                     /locus_tag="KRN00_002380"
     CDS             12409..13155
                     /gene="map"
                     /locus_tag="KRN00_002380"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBH1828241.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            13177..13446
                     /locus_tag="KRN00_002381"
     CDS             13177..13446
                     /locus_tag="KRN00_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBH1828242.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13484..13702
                     /gene="infA"
                     /locus_tag="KRN00_002382"
     CDS             13484..13702
                     /gene="infA"
                     /locus_tag="KRN00_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBH1828243.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13738..13851
                     /gene="rpmJ"
                     /locus_tag="KRN00_002383"
     CDS             13738..13851
                     /gene="rpmJ"
                     /locus_tag="KRN00_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBH1828244.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            14004..14375
                     /gene="rpsM"
                     /locus_tag="KRN00_002384"
     CDS             14004..14375
                     /gene="rpsM"
                     /locus_tag="KRN00_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBH1828245.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14411..14809
                     /gene="rpsK"
                     /locus_tag="KRN00_002385"
     CDS             14411..14809
                     /gene="rpsK"
                     /locus_tag="KRN00_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBH1828246.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14841..15464
                     /gene="rpsD"
                     /locus_tag="KRN00_002386"
     CDS             14841..15464
                     /gene="rpsD"
                     /locus_tag="KRN00_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBH1828247.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15542..16489
                     /locus_tag="KRN00_002387"
     CDS             15542..16489
                     /locus_tag="KRN00_002387"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBH1828248.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16510..16851
                     /gene="rplQ"
                     /locus_tag="KRN00_002388"
     CDS             16510..16851
                     /gene="rplQ"
                     /locus_tag="KRN00_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBH1828249.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16971..17804
                     /locus_tag="KRN00_002389"
     CDS             16971..17804
                     /locus_tag="KRN00_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH1828250.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17792..18658
                     /locus_tag="KRN00_002390"
     CDS             17792..18658
                     /locus_tag="KRN00_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBH1828251.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18652..19455
                     /locus_tag="KRN00_002391"
     CDS             18652..19455
                     /locus_tag="KRN00_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBH1828252.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19487..20218
                     /gene="truA"
                     /locus_tag="KRN00_002392"
     CDS             19487..20218
                     /gene="truA"
                     /locus_tag="KRN00_002392"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH1828253.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            20338..20769
                     /gene="rplM"
                     /locus_tag="KRN00_002393"
     CDS             20338..20769
                     /gene="rplM"
                     /locus_tag="KRN00_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBH1828254.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20798..21190
                     /gene="rpsI"
                     /locus_tag="KRN00_002394"
     CDS             20798..21190
                     /gene="rpsI"
                     /locus_tag="KRN00_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBH1828255.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21649..22401
                     /gene="cwlD"
                     /locus_tag="KRN00_002395"
     CDS             21649..22401
                     /gene="cwlD"
                     /locus_tag="KRN00_002395"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBH1828256.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         9084 a         2647 c         4653 g         6199 t
ORIGIN      
        1 gagtggggag ataagatagt agaattattc gagcaaatag atgagtatat accagctcca
       61 gagagagata cagataaacc attcttaatg ccagtagagg acgtattctc aatcacagga
      121 agaggaacag ttgcaacagg aagagtggaa agaggagtac taaaagtaca agacgaagta
      181 gaattagtag gattaacaga agcaccaaga aaagtagtag taacaggagt agagatgttc
      241 agaaaattat tagaccaagc acaagcaggg gataatatag gagcattatt aagaggagta
      301 caaagaaacg agatagaaag aggacaagta ctagcaaaga ctggatcagt aaaggcacac
      361 acaaagttta cagcagaagt atatgtactt aaaaaagaag agggtggaag acatacacca
      421 ttctttgatg gatatagacc acaattctat ttcagaacaa cagacgtaac aggagcttgt
      481 aagttaccag aaggaataga gatggtaatg cctggagata acgtaacaat ggaagtagac
      541 ttaataaact caatagttgt agaagaggga ttaagattct caataagaga aggtggaaga
      601 acagtagctt caggagttgt tgctacaata atagagtaat cctttactaa actaatggat
      661 ttaatataaa aaaagagggg gctaactcct ctcttttttg ttttttgttg acaagtagcg
      721 ctaaagcata tatactaaac tggtgccttg agacagatta acaatcaagt ttaaggttat
      781 gatgttgtaa tagaaaataa aattgaaaaa aacagaaaaa aaacttgaaa aaatgtaaca
      841 gatgatataa aatataatag tgtgcttgag agattaagaa aataataatt aaatcctagt
      901 gaaatacgaa ctgatatcga tttaaaagtt acaacacacc cggagcagtg tgtcggtatt
      961 ggttgtacgc aacttgaaaa ttaaacacgt gataaaggag ggaaaacaaa atggctaaga
     1021 atgaaaaaat aagaataaga ttaaaatcat atgatcacaa attattagat ttttcagcag
     1081 gtaaaatagt tgaaactgct aaaaaggctg gatcacaagt ttcaggacct gtgcctctac
     1141 caacagaaaa acaagttgta actatattaa gagctgtaca taagtacaaa gactctagag
     1201 aacaatttga aataagaact cataaaagac taatcgacat agctaatcca acacctaaga
     1261 cagttgactc attaatgaga ttagacttac cagcaggtgt agatatagaa ataaaattat
     1321 aagaacccct aagatattat cctatagatg attatcttag aatgattact ctaaaagatg
     1381 taatccgctg taagaattat aggaggtgct aatatgaaag gaatattagg caaaaaagtt
     1441 ggtatgactc aaatattcac tgataaaggt gtagttatac ctgtaacagc tgttgaagca
     1501 gggcctatgg tcgttactca aataaaaaca gttgataaag atggatacaa tgctatacaa
     1561 ataggttttg aagatgctaa agaaaaagct ttaaacaaac ctaaaaaagg acatttagct
     1621 gctgctaatg ttttaaagaa acatttaaaa gaatttagag tagattctgt agaaggatac
     1681 acagtaggac aagaaataaa agctgatgta tttgaaacag gtgcaaaaat agatgttact
     1741 ggaataagta aaggtaaggg attccaaggt ccaataaaaa gacatggaca aagtagaggt
     1801 cctgaaactc acggttctag ataccacaga agaccaggtt caatgggagc ttgttcttac
     1861 ccaggtagag tatttaaaaa caaaaaatta gctggacata tgggaagcgt aaaggtaaca
     1921 gttcaaaact tagaggttgt taaagtagat gctgacaaga accttatatt agttaaagga
     1981 gctataccag gagctaaagg ttcagtagta actataaaag aagctataaa ggtttctaaa
     2041 taatgactaa cctagagaaa ggaggaataa caatgccaaa attaaatgta ctaaatgtta
     2101 gtggacaaaa cgttggagaa atagaattat cagattctat atttggcgta gaagttaatg
     2161 gacatgtttt atacgaagtt gtaaaaaatc aattagcaaa taagagacaa ggaactcaat
     2221 ctgctaaaac tagagcagaa gttagaggtg gcggaagaaa accttggaaa caaaaaggaa
     2281 caggtagagc aagacaaggt tctacaagat ctgtacaatg ggtaggtgga ggagttgctt
     2341 ttgcacctaa accaagaagc tacaaatata cattacctaa gaaggtaaga agattagcta
     2401 tgaagagtgc tttatcttca aaagttcaaa atagtgaagt tatagtatta gatgcattaa
     2461 acatggatgc tcctaagact aaagaatttg ctcaaatatt aaacaatata aatgctgcta
     2521 aaaaagcttt agtagttata gctgacaaaa acgataacgt aataaaatca gctagaaata
     2581 tagaaggtgt tcaaactgca ttagttaata ctatgaatgt atatgatata ttaaaatacg
     2641 attcatttat aataactaca gatgctgtta aaaaagtgga ggaggtgtac gcataatgac
     2701 taatccacat gatgtaataa taagaccagt tgtaactgag cacagtatgg ctgaaatggg
     2761 tgaaaaaaaa tacacttttg ttgtggctaa agatgcgaac aaaactgaaa taaaaaaagc
     2821 agtagaaaaa gtattcggag ttagtgttga taaagtaaat actttaaact acgatggaaa
     2881 agttaaaaga atgggtagaa ctcaaggaag aacatcaagc tttaagaaag cagtagttaa
     2941 attaactgct gatagtaaag aaatagaatt cttccaagga atgtagtatt ataacaaacg
     3001 aaggagggaa aacagatggc tataaaaaag tttagaccaa cttctcctgc cttaagacaa
     3061 atgacagttt tagtttctga tgaaataaca tgtaatcaac cagaaaaatc tcttttagtt
     3121 aacttaaaga aaaatgctgg tagaaacgta catggtagaa taactgttcg tcatagaggt
     3181 ggaggacaaa aaagaaaata tagaataata gattttaaaa gagataaaga tggtatacct
     3241 gctaaggttg ctactataga atatgatcca aacagaactg caaatatcgc attattaaac
     3301 tatgctgatg gagaaaaaag atatatatta gctccagttg gaattaacgt tggagatact
     3361 atattatcag gattaggtgc tgatataaaa ccaggaaact gtttagcatt aaaagatatg
     3421 ccagttggta ctatcattca taatatagaa ttaaagccag gaaaaggagc tcaattagtt
     3481 agatctgctg gagtttctgc acaattaatg gctaaagaag gaaaaaatgc tttattaaga
     3541 ttaccatcag gtgagatgag attagtaagc ataaactgta aagctactat aggtcaagtt
     3601 ggaaatatag agcatggtaa cgtagttatc ggtaaagcag gtagaaaaag acatatggga
     3661 ataagaccta ctgtaagagg ttctgtaatg aaccctaatg accatccaca cggtggaggg
     3721 gaaggtagat ctccaatagg tagaccatct cctgttactc catggggtaa accagctctt
     3781 ggatacaaaa ctagaaagaa aaataaagct tcaaataaac taatagtatc aagaagaact
     3841 aagtagtaaa tttatttttg ctcggaaagg aggaatataa atgtcaagat caactaaaaa
     3901 agggcctttt gtccatgcaa gacttttaaa gaagatagaa gctatgaatg ctagtggaaa
     3961 taaagaagtt ataaaaactt ggtcaagatc ttcaactgta tttccacaaa tggtagaaaa
     4021 cactatagct gttcatgatg gaagaaaaca tgttccagta tatataacag aagatatggt
     4081 tggacataaa ttaggtgagt tcgttcctac tagaactttc aaaggacata aggatgacga
     4141 aaaatctaat aagagaaaat aattaaatta tgactaagaa aggaggaata acaatggaag
     4201 caaaagctac tgctaaatac gtacgtgtat caccaagaaa agcaggccaa atatgtgacc
     4261 ttgttagagg aaagaatgtt gatgaagcat tagcaatatt aaagtttact ccaagaggag
     4321 cagcttcaat aatagctaag gttgtaaaat cagctaaagc taacgcagaa aacaatcacg
     4381 aaatggatac tgaaaaatta tatatagcat caatagttgc taatcaagga ccaacaatga
     4441 agagattcat gcctagagct atgggtcgtg caactacaat aagaaaaaga acttctcata
     4501 tagaggttgt tgttaaagaa aaaaaataat taatagatag gagggaaagt aatgggtcaa
     4561 aaggttaatc cacacggctt aagggtcggt gttataaaag attgggactc aagatggttc
     4621 gctactgata aaaaagagtt cggaaactta ttattagaag accataatat acgtaaattc
     4681 ttaaagaaaa gattatactc agctggagtt gctaagatag aaatagaaag atcagctaac
     4741 aaaataaaaa tggacttaca cgttgctaag cctggtgtag ttataggaag agctggtgca
     4801 ggaatcgaag cattaaaagc tgaattagaa aaaatgacaa agaaaactat aatagttaat
     4861 atagtagaag taagaagtac agataaaaat gctcaattag tagctgaaaa tatagcttta
     4921 gctatagaga gaagggttgc tttcagaaga gcaatgaaac aagctataca aagagcaatg
     4981 aaatctggtg ctaaagggat aaaagtttct gcttcaggaa gattaggtgg agctgaaatg
     5041 gctagaactg aaggttatag tgaaggaaat gtgccactac aaactttaag agcagatata
     5101 gattatggtt tcgctgaagc tgatacaact tatggaaaaa tcggtataaa agtttggata
     5161 tgtaatggtg aagttttacc aactagagac ggtgtaaatc caagagaaga aagcagaaag
     5221 agcgatagaa gagacaacaa gagagataat agaagaaacg atagaagagg aaatgacaga
     5281 agaggaaatg ataacagagg aaactacaga ggacaaagac ctcaaggtgg atcaagacct
     5341 caaagaactg aaaacaaagg aaattaataa tagttaggtt caaggaagga ggaaaaatac
     5401 tcatgttaat gccaaaaaga gtaaagcgtc gtagagttca tagaggaagc atggctgggc
     5461 aagctcataa gggtaataaa gttacttatg gtgagtttgg attagtagca ttagaagctt
     5521 cttggataac ttctaatcaa atagaagctg ccagaatcgc gatgactaga tatataaaaa
     5581 gagggggaaa ggtttggata aaaatattcc ctcataaacc agtaacaaga aaaccagcag
     5641 agactcgtat gggtgcaggg aaaggttctc cagaatattg ggtagctgta gttaagccag
     5701 gaagagttat gtttgaatta gcaggtgttt ctgaagataa agcaagagaa gctatgagac
     5761 ttgctgcaca taaattacca atcaaatgta aatttgttaa aaaagaagat ttagaagtaa
     5821 agggtggtga ataggatgaa agctaaagaa ttaagagatt taacaagcga agagctaatg
     5881 aacaaattaa acgacttcaa aagtgaatta tttagcttaa gattccaatt agctactggt
     5941 caattagaaa atacagctag aataaagttt gttaagaagg atatagcaaa agttaaaact
     6001 gttcttgctg aaagaaagtt atacgaaact agagcttaat ttggaaagga ggctttttaa
     6061 acatggaaag aggaagaaga aaagttagaa taggccgtgt tgttagtgat aagatggata
     6121 aaacaatagt agtagctgtt gaagaattcg tacgtcatcc actatataat aaacgtgtta
     6181 agagaactaa gaaattcaag gctcatgatg aaaagaatat atgtaacatc ggagatagag
     6241 ttaaaataat ggaaactaga ccattatcta aagataagag attcagacta gttgaagttg
     6301 ttgagaaagt taagtagttt ttgaagaagg agggattacg atatgataca acaagaatca
     6361 cgtctaagag ttgctgataa ctcaggagct aaagaacttt tatgtatacg tgttctaggc
     6421 ggaagtaaaa gaagatatgg taacataggc gacgttatag ttgctactgt taaaagtgca
     6481 acacctggtg gagttgtaaa aaaaggtaag gttgttaaag ctgttatagt aagaagcaaa
     6541 caaggcgtaa gacgtaatga cggaagctat atatcttttg atgaaaatgc tgctgttata
     6601 ataaaggacg ataaaactcc agtaggaact cgtatattcg ggcctgttgc tagagagtta
     6661 agagacaatg aattcatgaa aatagtttct cttgctccag aagtactata attaaggagg
     6721 tgcaatagga catgatgcgt gttaaaaaag gtgacactgt tgtagttata gcaggtaaag
     6781 ataaaggtaa aaaaggttca gttttaaagg tatatcctaa aactagcaaa gtgttagttg
     6841 aaggtgtaaa tgtaataact aaacatcaaa aaccaagtgc tatgaaccaa caaggtggaa
     6901 taataaataa agaagcccca atacacatat ctaatgtaat gccatttgat cctgaaacag
     6961 gaaaaggcgt tagagtaaga tatgaagtaa aagatgggaa caaagtaaga gtatcagcaa
     7021 agagcggaaa agaattataa taaatattgc ttgaaaggag ggaccttaaa tggcttctag
     7081 attacaagaa aaatacatga aagaagttgc tcctgcttta atggagaaat ttggatacaa
     7141 aaacgtaatg gagataccta agttaaataa aatagttatt aacatgggta taggtgacgc
     7201 tagagaaaat ccaaaaggat tagaaaaagg cgttgaagaa ttagaaatga tatcaggaca
     7261 aaagcctgtt ataactaaag ctagaaaatc tgttgctaac ttcaaattaa gagaaggaat
     7321 gccaatagga acaaaagtta cattaagagc tgacaaaatg ttctacttta tggacaaatt
     7381 agtttcagtt tctttaccaa gagttagaga ctttagagga gttaacccta atgcttttga
     7441 tggtagagga aattatgctt taggagttaa agaacaatta atattccctg aaatagaata
     7501 tgataaaata gataaagtaa gaggaatgga tataatattt gttactacag caaaaactga
     7561 cgaagaagct cgtgaattat taaaattatt aggaatgcca ttttctaagt aagcaaagga
     7621 gggattcccg tggctagaaa agcgatggtt gttaagcaac aaagaaagca aaagtacgct
     7681 actagagaat acactagatg tactatatgc ggaagaccgc attcagtttt gaaaaaattt
     7741 ggtatatgcc gtatatgctt tagagaatta gcttataaag gtcaaatacc tggtgttaga
     7801 aaagcaagct ggtagaagct tgattagaat ggaaggaggg caacaaaatg acaatgacag
     7861 atccaattgc agatatgctt actcgtataa gaaatgctaa tgttgttaag catgaaactg
     7921 tagatgttcc agcttctaat atgaagaaag aattagctag aatcttatta gaagaaggtt
     7981 tcataagagg ttatgatgtt atagaagatg gaaaacaagg tatcataaga atacaattaa
     8041 agtacggaca agaaggcgaa agagttataa caggtcttaa gaaaatatct aagcctggaa
     8101 tgagagttta cgctgctaac catgagatac caaaagtatt aaacggatta ggaatatcag
     8161 ttatatctac ttcaaaagga atattaactg acaagcaagc tagaaaagaa aatgttggtg
     8221 gagaagtaat ctgctacgtt tggtaattaa tatgaacaat gtaaggaggt gcgaccatgt
     8281 caagaatagg tgttaagcca ataataatac cagcaggtgt tgaagttact atagctgaag
     8341 gaaatttagt tacagtaaaa ggtccaaaag gaactttaac taaacaatta agtgctgagt
     8401 taaacataaa aaaagaagaa aatacaataa tggttgaaag accaactgat aataaaaaac
     8461 atagatcttt acacggacta actagaactt tattagataa tatggttgta ggtgtaaata
     8521 ctggtttcga aaagaaatta gaattaaaag gtgttggata tagagctcaa aaacaaggaa
     8581 agaaattagt tatgaactta ggtttctctc atccagttga gatggaagat ccagaaggaa
     8641 taactgttga agctccaaac caaacagagt taatagtaaa aggtatagac aagcaattag
     8701 tagggaatta tgctgctaag ataagagctt ggagaaagcc agagccatac aaaggtaaag
     8761 gtataaaata cgttgatgaa gtaatcagac gtaaagaagg aaaaactggt aaaaaataat
     8821 accaaaactt aaacgctaga aaggagtgag ctaggtgtta aaaaaggctg ataaaaatgc
     8881 taatagactt caaagacata agagagttcg tagaaaaata agcggtactt ctcaaagacc
     8941 aagattatgt gtatttagaa gtgctaacaa tatatatgct caaataatag atgacacaaa
     9001 aagagtaact ctagttgctg catcttcttt agaagcagaa gttaagagtg ctgtcaatca
     9061 tacaggaaac aaggaagcag ctaagaaagt tggagaatta gttgctaaaa aagctgttga
     9121 aaaaggaatc actgaagttg tatttgacag aggtggatac ttatatcatg gaagaattca
     9181 agaattagct gaaggtgcta gagaagctgg tcttaagttc taatacgaag gagggaaaaa
     9241 tacatgctac gtcgtaagcc gatagatgca ggacaacttg acttacaaga aaaagttgtt
     9301 gaagtaagac gtgttactaa ggttgtaaaa ggtggtagaa atttcagatt tgcagcatta
     9361 gtagttgttg gagatgaaaa cggacacgtt ggtataggtg ctgggaaagc aatggaagta
     9421 ccagacgcta taaaaaaagc agttgaagat gctaagaaaa atctaatagt agtgccaata
     9481 gttgggacta caattcctca cgaagtacgc ggacactttg gtgctggaaa tatattaata
     9541 atgcctgctg tagaaggtac aggagtaata gctgggggac ctgctagagc cgtacttgag
     9601 ctagctggac taaaagacgt tagagctaaa tctttagggt ctaacaatcc aagaaatatg
     9661 gtaaatgcta caatagaagg acttaattct ctaaaaacag ttgaagatat agctaaactt
     9721 agaggtaaaa aagttgaaga acttctaggg taaggaggta gtgtaaaatg gctaaattac
     9781 aaataaagtt agttagaagt gttataggaa ctactcctaa ccaaaaaaag aatgttgaag
     9841 cgttaggatt aagaaaaaga gaacaagttg ttgtaaaaga agacaatgct caaacaagag
     9901 gtatgataaa taaagtaagt cacttattag aagtaactga aatagctgaa taatttttat
     9961 aaagtagtgc aaggaggtgc aatccatgaa gttacatgag ttaaaacctg ctgaaggtgc
    10021 agtaagagct aagagaagat taggtagagg tactgcaact ggacaaggta aaactgcagg
    10081 acgtggacaa aaaggtcaat ggtctcgttc tggtggtgga gtaagagtag gatttgaagg
    10141 tggacaaatg ccactagcta gaagacttcc taagagaggt ttcaataaca tatttaagaa
    10201 agtttacaca gaagttaatg ttgaagtttt aaacagattt gaaaatggaa cagaaataac
    10261 tgcagaatta ttaaaatcta ctaaaactat aagcaaaata ggtaaagacg gaattaaaat
    10321 cttaggtgaa ggtaatttag agaaagcttt aactgttaaa gctgctaaat ttacagcttc
    10381 agctcaagaa aaaatagaaa aagctggtgg aaaagcagag ttagtataat aacctgctaa
    10441 tctcctagcc agtacaggcg gggtgaatta gcgtgctgtc aaaattaaaa caagcttgga
    10501 agattaaagc agtaagaaaa aaagtaatgt atacacttat gatgatcgtg atattcagaa
    10561 taggtactac tataccagtt ccaggcatag acactagtat tatacaaaag atggtaggcg
    10621 gcaatagtct actttctctg tataatatgt ttactggtgg agcatttagt aacttttcac
    10681 tatttgcttt aggtataagt ccatatatca ctgcatcaat cataatacaa cttctaacag
    10741 taggttttga aagtttagca gaacttcaaa aatctggtga agaaggaaag aaaaaaatca
    10801 ataagtacac taaatataca gcactagctc tagcagttgt acaagctttg ggaattacat
    10861 taggaattgt aagaagtgct ttaatatcaa atagtgtgtt ttttatcaca actgttgtaa
    10921 taacattagt ttcagcaagt atgttagtaa tgtggattgg ggacaaaatt actgaaaaag
    10981 gaatcggtaa tggtagttca gtaataatat ttgcaggtat aatatcaaga atacctacag
    11041 atgttattaa aatatcgcaa caagttaaat ctggcgaagt tgcaccttgg gttatagtga
    11101 ttctagctgt agttatatta cttacagtaa caggagttac atttatacaa gaagcaacta
    11161 gaaagatacc tgtacaatat gctaaaagag ttgttggaag aaaaatgtat ggaggacaaa
    11221 gttctcatat accaatgaaa gttaaccagt caggagttat gcctataatt tttgctagtt
    11281 cacttttagc tttccctcaa acaatagcta tgtttatggg tccaaatgct caggcttttg
    11341 ttcaaaaata cttaagtatg gcaacagaac aaggattttg gacatataga tcaattgaga
    11401 ttctacttat aattttcttc tcatattttt atacaactgt atcatttaat acagaagaca
    11461 tatctaaaaa tatgaaaaat aatggtggat ttataccagg tataagacca ggtgagccta
    11521 ctatggatta tttaaataga attttaacta gattaacttt agctggagct actttcttag
    11581 caataattgc tatggtgcca gctcttacaa cacattatat gaaagtaaat atgagtctag
    11641 ctgggacttc attgctaatc gttgttggag ttgctttgga gcttaagaga cagttagagt
    11701 caaacttagt tatgagaagc tatcaaggtt tcttaaaata aaatggagat ggataatatg
    11761 agaataatat tacttggacc tccaggtgct ggtaaaggta ctcaggcggc aggaatagta
    11821 gaaaaataca atatacctca tatatcaaca ggagatatat tcagaaagaa tataaaagag
    11881 ggaacagaac ttggaaaaaa agctaaagaa tacatggacc aaggtttatt agtaccagat
    11941 gagttaactg taggtttagt tactgataga atatctcaag aagattgtaa aaatggattt
    12001 atgttagatg gatttccaag aaatgtagca caaggagaac atttagatat cttcttaaaa
    12061 aatgctggta tatcactaga taaagttgtc aatattgaag ttgataagag tatattagtg
    12121 tctagagcag ttggtagaag aatatgtaag tcttgtggag ctacttacca tgttgagttt
    12181 aatcctccta aagtagaagg tgtatgtgat gtatgccaag gagaattata tcaaagagct
    12241 gatgataatg aagaaactgt atctaagaga atacaagttt atctagatga aactaagcct
    12301 ttagtagatt attatagcaa acaaggtata atagcagata taaaaggtga tcaagcaata
    12361 gataaagtat ttgaagatat tgtcgcagcc ttaggaagtg gaaaataaat gattatcttg
    12421 aaatcaaaaa aagaaataga acttttaaga gaagcaggta aaatagttgc tgacactcat
    12481 gaagttttaa gaaaagctat ttctccggga atatctactt tagaattaga taaaatagct
    12541 gaagagaata taagaaaata caatgcagaa ccttctttta aaggatatgg aggttttcca
    12601 ggaagtatat gtgcttctat caatagagag gtagtacatg gtattccagg agaaactata
    12661 ttacaagaag gtgacattgt aagtttggat ataggagcct attataaagg atatcatggt
    12721 gattctgcga aaactcacgg agtaggcatg atatctgaag aagataggaa attgatagaa
    12781 gtaactagag aaagcttcta tgaaggaata aaatttgcta aattaggata tagactttca
    12841 gatatctcac acgcagtaca aacacacgtt gagaaacatg gtttctcggt agttagagat
    12901 ttagtgggtc atggagttgg agcaaatctt catgaagacc cacaagtacc taattatgga
    12961 ctcccaggaa aaggaccaag acttagagaa ggaatggtta ttgctataga gccaatggtt
    13021 aatgcaggtc gttatcatgt aaagactcta tcagatgggt ggacgactgt tacaatagat
    13081 ggaaaaaaat cagctcatta tgagcatacg atagcaatta ctgaacatga acctttgata
    13141 ttgacaaagt tgtaatttaa aaagtaggtg aaaaaagtgc tatcagataa tttaagtata
    13201 ggtcaagttg tcaaagtttc attaggacga gataaaggaa atttattctt tgtagtcaaa
    13261 ataattaata atgaatatgt attaatagct gatggaaaaa agagaaaact tgacaaacct
    13321 aagttaaaga aagtgaagca cttaaaaaaa tataatttta ttaatgatga agttagaaaa
    13381 agagtagtat ctggacaaga gattacagat tcttttttaa gagctgaact tactaagtta
    13441 aattagataa tttaacttat tgaaatggag ggctggttag ttaatggcca aaaaagatgt
    13501 tatagaatta gaaggtacag tttcagaagc tttacctaat gctatgttca aagttaaact
    13561 agaaaatgga catgagatat tatgccacat ttctggaaag ctaagaatga acttcataag
    13621 aattcttgaa ggtgacaagg tgaatgttga actttctcca tatgacctta caagaggaag
    13681 aattacttgg cgtaagaagt agactatatt aatatttagt ctaaggaggg attaataatg
    13741 aaggttagac catcagtaaa accaatatgt gaaaaatgta aagtaataaa aagaaaagga
    13801 aaagtaatgg ttatctgtga aaatccaaag cataagcaaa agcaaggata agaaattatt
    13861 actagcattt tgttaaattt tatagtataa tactatattg tgatgttaac aaaagaacgt
    13921 taaaatcgtt gaacaatctg gcgtaggatt ggcatatgat gtgaagtttt aaacactaaa
    13981 aactatgtgt aggaggtgcg atcatggcaa gaatagctgg ggtagattta cctagagaaa
    14041 aaagagcgga gataggctta acttatatat atggtatagg taaagcaact gctaacgaaa
    14101 tattagctaa ggctgagata aatccagata ctagaataaa agatttatca gaagatcaag
    14161 ttaatgagtt aagaaaagtt atagatgacg atttcttagt tgaaggtgac ttaagaagag
    14221 aaattgcttt aaacataaag agattaagag atataaaatg ttatagagga ataagacacg
    14281 ctaaaggtct tccattaaga ggacaaagaa ctaagactaa tgctagaact agaaaaggtc
    14341 ctagaaaaac agtatctcgt aaaaagaaaa aataaataaa taataactag atgaaggagg
    14401 gaaaaggaaa atggctaaac caaaaaagaa agttacacgt attagaagaa gagaacgtaa
    14461 aaatatagaa cgtggtcatg ctcatataca atcaactttc aataatacaa taataacttt
    14521 aactgacgtt cacggaaatg ctatatcttg ggcaagttct ggacaattag gattcaaagg
    14581 atcaagaaaa tcaactccat ttgcatctca aatggctgct gaaacagctg caaaagctgc
    14641 gatggaacac ggactaaaaa gtgttgaggt attcgtaaag gggccaggtt caggaagaga
    14701 agctgcaata agagctttac aagcaactgg actagaagta actatgataa aagacgttac
    14761 tccaatccca cataacggat gcagaccacc aaagagaaga agagtgtaat taataagagt
    14821 acaataggag gtgtagataa atggcaagat atacaggtgc atcatgtaga caatgccgta
    14881 gagagggaat gaaattattc cttaaaggtg atagatgtta tacagacaaa tgtgctatag
    14941 taaaaagaaa ctatgctcca ggtcaacatg gccaaggaag aaagaaagtt tctaactatg
    15001 gattacaatt aagagaaaaa caaaaagtta aaagaatata tggagtttta gagactcaat
    15061 ttagaaattt atatgaacgt gctgaaaata tgcctggtaa agcaggtgag aacttattaa
    15121 gtttattaga gagaagatta gataatgtag tttacagaat gggactagca tcttctagaa
    15181 aagaagctag acaattagtg actcatggtc atttcacttt aaatggaaat aaagtagaca
    15241 taccttcatt aatagttaag gttggagatg ttatagaagt taaagagaaa tcaagatctt
    15301 ctgcaaaatt caaaaattta gtagaagtta actcaagaat agctcctaag tggttagaag
    15361 ctaatgtaga aggaatgaca gcaaaagtag ttggtgttcc aacaagagaa gatatagatc
    15421 ttgagatagc agagcactta atcatagaac tttactctaa ataataagca cacttttaaa
    15481 aattatttta aaattttgtt taccctcagt ggattactga attttaagga gggttttgtc
    15541 catgatagaa atagaaaagc caaaagtaga tatagttgag cttagcgaag actatagata
    15601 tggtaagttt gttatagagc ctctagaaag aggatatgga ataactatag gtaacgcatt
    15661 aagaagaata ttattatcat cattaccagg tgtagcagtg aatgctataa aaatagatgg
    15721 agttcttcat gaattttcaa caatacctgg tgttaaagaa gatgttactg agataatatt
    15781 aactttaaaa gagctttcag caactataga tggtgaagga agtagaacac ttaaaataga
    15841 agctcaagga ccatgctcta tcacaggtgc agatataatc tgtcctccag atgttgaaat
    15901 attaagtaaa gatttagcaa tagctacatt agatgataat gctaaactta atatggagat
    15961 atttgtagat aaaggtagag gttatgtttc tgctgaagaa aataaaacag agaatgttcc
    16021 aataggtgtt ttacctgtgg attcaatata tactcctgtt gagaaggtta gttatcatgt
    16081 ggaaaacaca agagttggtc aaaaaacaga ttatgataaa ttagtactag aagtttggac
    16141 taatggtagt ataaatcctc aagagggaat atcattagct gcaaaggtat tagttgagca
    16201 tttaaactta tttatagact taactgaaca tgtaagtagt gttgaaatca tggtagaaaa
    16261 agaagaagat caaaaagaaa aagttcttga aatgactata gaagaattag atttatcagt
    16321 tagatcatat aactgtttaa agagagcggg aattaataca gttgaagaat tagctaataa
    16381 atctgaggat gatatgatga aggttagaaa cctaggtaag aagtcattag aagaggtaat
    16441 acaaaaacta gaagaacttg gattgggatt aaaaccaagt gaagaatagc gagcaaagga
    16501 gggataagaa tggctaagta ccgtaaatta ggacgtgaaa cagctcacag aaaccttatg
    16561 ttaagaaact tagtaacttg cttactaaga agtggaagaa tagaaactac agtgactaga
    16621 gcaaaagaaa ctcgtagaat ggctgaaaag atgataactc ttgctaagag aggagatctt
    16681 catgctagaa gacaagtttt agcttatgtt atggatgaaa cagtagttaa taacttattc
    16741 acagatttag ctccaaaata tgctgagaga aatggtggat acactagaat aataaaaata
    16801 gggccaagaa aaggcgatgc tgctgaaatg gcttttatag aattagtata gtaaggaaag
    16861 gattaggctt gatggcttaa tctttttttt atttttttga ctaaggtatg atataataat
    16921 gtgtaaaatg atttttataa gttattgctt actaaaagga gtatgagtta atggataata
    16981 tagtaaaggt aaataatatt tcgtttgagt atattacaga tgaagcaaaa cttaaagcaa
    17041 tagataattt aagcctagat gttaaaaaag gagaatttgt tgcgataata ggacataatg
    17101 gttctggtaa gtctacttta tctaaaaact taaatgctat tcttatgcct actgaaggaa
    17161 atattcttat tgatgatatg gatactaaag aagaagaaag attatgggat ataagacaaa
    17221 ctgcaggcat ggtatttcaa aatccagata atcaaatagt tgctactata gtagaagaag
    17281 atgttgcatt tggacctgag aacttaggta tagaaccaaa agaaataaga cgaattgtag
    17341 aggagtcttt aaaaagtgta ggtatgtatg atttaagaga tagacagcct catttgttat
    17401 caggaggtca aaagcaaaga gttgcaatag caggaattat tgctatgagg cctaaatgta
    17461 taatatttga tgaagcaaca gcaatgttag atccatctgg aagaaaagaa gttatgaaaa
    17521 caataaaaag acttaataag gaagaaaata taactgttat acatataacg cactttatgg
    17581 aagaagcagt agaagctgat agagttgtag ttatggaaaa aggaaagaaa atcttagagg
    17641 gaactcctag agaagtattc agtaaaataa agatgttaaa ggaaatcggt ttagatgtac
    17701 cttgtatgac agagttatct agtttattaa tagaagaagg tataaatatt agtagtgata
    17761 tattaactgt ggatgagatg gtgatggaat tatgtcaatt atagtaaaga atttaacaca
    17821 tatatataat gaagggatgc cttttgcaag taaggcactt gatgatgttt cttttgagat
    17881 taaagataga gattttgttg gtcttatagg tcatacaggc tcaggaaaat ctacattaat
    17941 acaacattta aatggattac taaagccttc ctcaggagaa atatttataa atgattttaa
    18001 tataacagat aaaaacttga atttaactga gattagaaaa agagtagggg ttgtatttca
    18061 atatccagaa taccaattgt ttgaagaaac gattgataaa gatatagctt ttggaccctc
    18121 taatttaggc ttagaggagt ctgagataca taacagggta aaagcatcaa tggaagctgt
    18181 aggacttgat tatgagggat ttaaagacaa atctcctttt gaattatctg ggggacaaaa
    18241 gcgtagagta gcaattgctg gagttatagc catgaaccca gaagttctca tattggatga
    18301 accaactgct ggtcttgacc ctggtggaag agatgaaatt tttaacttaa taaaagactt
    18361 acatgaaaaa aagaatatga ctataatact atcatcacat agtatggatg atatggcaaa
    18421 gttagcaaaa actttaattg ttatgaatca tggtagcgta gaatttatgg gaactcctag
    18481 agaagtattt aaatcaaatg ctagtaaatt aaaagatata ggattagata ttccacaagt
    18541 tttagagctt gcattgaaat tgagagaaaa aggctttgac atcagtgagg atatattgac
    18601 tttagaagaa gcaaaacagg aaatattaaa agttgtgaga ggacgaggat tatgttaaaa
    18661 gatataacta tagggcaata ctacccaaca agttctgcta ttcataaatt agatccaagg
    18721 ataaagcttg tagcgacaat tgtatttatg gtatctatat ttgtagtaaa taaattttgg
    18781 ccttatatag tagttttatt atgtttatta gctatgataa aattggctaa tataccagtc
    18841 aaatatattg ttaagggtgt taaacctctt aaatggatta ttttgtttac atttcttata
    18901 aatatttttt tcttaccagg tgatgaaata tggtcatttg gatttttagc tattacaaaa
    18961 cagggtctaa gacaagcaat ttttatggca ataagattaa tatttttagt agttggtaca
    19021 tcattgctta ctttaacaac ttcaccaata gaattaactg atggaataga gagattgttg
    19081 aatccattta agaaaattgg tttgccagtt catgaacttg caatgatgat gacaattgct
    19141 ttacgtttta ttcctacatt gttagatgag acagacaaaa taatgaaggc tcagatgtct
    19201 agaggtgcag attttgaaag taagaatctt ataaatagag caaagaattt agtaccactt
    19261 ttggtacctt tatttgtaag tgcatttaga agagctgatg aattggctat ggccatggag
    19321 gccagatgtt acagaggtgg acataatagg actaagatga gagagtctgt tatatcaaga
    19381 agggattata tggcatgtgt atttcaggtt gtttatctgg gagcaattat agctactaga
    19441 tttatagcaa tttaattaat aagttataga tataatgagg taaagtatga gaaatataaa
    19501 aattaaaatc caatacaatg gtaagaatta ttgtggatgg caaaagcaac ctgattcttt
    19561 agggatacaa ggtacaattg aaagggctat atatgatata acaaaagaag aaaccagtct
    19621 tatagggtct ggtagaactg attcaggagt tcatgctatt ggtcagattg caaattttaa
    19681 aattaattca ggtataagta tagaaagtat accaatggca ctaaatgcca agttgccaaa
    19741 agacatatca gttatagaag catgtgaagt aaatgatgat tttcactcca gatacagtgc
    19801 aaaaggtaaa acatataaat atttagtata taatagcaag tttagaaatc caatacttag
    19861 tgagatatca tatcaagtaa aatatgaact tgattttgat aaaatgtgtt cagaagcaaa
    19921 aagtttatta ggaacacatg attttaaagg ttttatgagt tctggttcat ctgtaaaaga
    19981 tacagttaga acgatatatg atattgatat aagtaaaaaa gatgacttga ttacttttga
    20041 gattagtggt aatggttttt tatataacat ggtgaggatt attgttggaa cacttgttga
    20101 tatgggtcgt ggcagaatta acgaaccatt tttagatata atacaatcaa aaactaggtc
    20161 aagatgtgga catacagctc cagcacaagg attatttctc aaaaaagttc attattaact
    20221 tgacacacca ggctacatgt attaaaatat atgagaatgt gttaataagt ccacttgccc
    20281 cggacttgac ataaacggta aaaaaatttt atgaaaagta gttaaggagg gacagttatg
    20341 aaaagttata tagctaagcc agctgatgta caaagaaaat ggtacttagt tgatgctgaa
    20401 ggaaaaacat taggtcgttt agcaacagaa attgcgacag tattgagagg taaacataaa
    20461 ccaacattta ctcctcacgt tgatggtgga gattttgttg ttgtagtaaa tgcagaaaaa
    20521 atagttttaa gtggtaagaa attagatcaa aaatattaca gataccatac tggttatgta
    20581 ggtggattaa aagaaatatc ttacagagat atgatggata agaaaccaga agaagttata
    20641 tcacatgctg taagcggtat gttacctaaa aataaattaa gaagcagaat gatgactaga
    20701 ttaagagtat ttgcaggtgc tgagcacact catgcagctc aaaatccaga agttttaaac
    20761 tttaaataag attaataggt gaaaggagga gtttataatg gctaacgttc aatattatgg
    20821 aactggaaga agaaaaagtt ctgttgctag agtaagacta gttgcaggtg aaggaaatat
    20881 attagtaaat ggaagagcat tagaaaatta ttttaattat gagacattaa taagagatgt
    20941 taaacaacca ttagttttaa ctggtaatga aaataaatat gatgttatag taaaagttga
    21001 aggtggagga ttcactggac aagctggagc tataagacat ggaatatcta gagctttatt
    21061 aaaagctgat ttagatttaa gacctgcttt aaagaaagaa ggtttcttaa ctagagatgc
    21121 aagaatgaag gaaagaaaga aatacggatt aaaagcagca agaagagctc cacaattctc
    21181 aaaaagataa ttacttattt ttttggaaaa gcaaaatcct ttatttactg ttattcagaa
    21241 agtattggta ttttaaaaat gttgggttaa gttaattatt gatatataat aaaataataa
    21301 gatatcttat taggatgttt ttcattaaga agaacatcct ttttattttg actatttaat
    21361 aaaaaacata tgctaataac atttaaattt tatttttata atattgtaat ttaaaagttt
    21421 atataaggtt atatatttta agatattatt taacaatata aattctgaat atacgttatc
    21481 aaaatttata atataaacta agtataattt attgtatagt attgaatgtt agataaacat
    21541 agtgaattaa atagggacag aaatataata tcattacata ataatatatt aataccaata
    21601 aataaagata tatcaatatt aaaaaaattt aaatgtttgt actaatatat ggaatattat
    21661 agtgttttta taagtataca tatacagggt gatgttgtga gaaagtacat aaaacatata
    21721 atttttagtt ttgcaatgat atgtctagta gtagtatcca tatttgaaat taaaaatatt
    21781 tctgaagatg ttatcaagta tatgccagta acaaacaaaa ctataatttt agatgctggt
    21841 catggaggca ttgatccagg tgcattaaat aaggataaga gtacatctga aaaggatatt
    21901 aacctagcaa taacacttaa gcttagagag cttatagaat caagtggtgg ccttgtaata
    21961 ttaactcgag aagatgacag tagcctttat aaagaagaaa ataataaaac tacaagacaa
    22021 aaatataatg agaatttgaa aaatagaaaa gaaataatat ctaattctaa tgccaatatg
    22081 tttgtctcta tacatcttaa tgcatttgaa caatcaaaat actatggagc tcaaactttt
    22141 tatcctaaag acaaacaaga cagtaaagaa ttatcgaagt gtattcaaga agaacttaaa
    22201 agagtagtag ataagacaaa caacagagaa gtcaaaccaa gggatgatat atatcttttg
    22261 aaagaaaata atattccatc agtactgata gaatgtggtt ttttatcaaa tgaaaaagag
    22321 tgtaaactct taactgatga aacatatcaa gaaaaaatag catgggcaat ctacatagga
    22381 atacaaaaat atttaagttg aaataactat aaaaataggt ctaaatatgt aaatagcttg
    22441 tattaaagca gttaaaatgc attaatatag gctattttta ttttgacaaa aaaatattta
    22501 aaataaaagt taaaaagttg ttgacttaga ataatataga tgatattata tatgagtgcc
    22561 caaaaggagc accaaaataa gac
//
LOCUS       DAEQAF010000058        22229 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.060, whole genome shotgun sequence.
ACCESSION   DAEQAF010000058 DAEQAF010000000
VERSION     DAEQAF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22229
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.060"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            444..1514
                     /locus_tag="KRN00_002396"
     CDS             444..1514
                     /locus_tag="KRN00_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828257.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            1498..2367
                     /locus_tag="KRN00_002397"
     CDS             1498..2367
                     /locus_tag="KRN00_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBH1828258.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            2411..3271
                     /locus_tag="KRN00_002398"
     CDS             2411..3271
                     /locus_tag="KRN00_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBH1828259.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            3302..4606
                     /locus_tag="KRN00_002399"
     CDS             3302..4606
                     /locus_tag="KRN00_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1828260.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            4669..5931
                     /locus_tag="KRN00_002400"
     CDS             4669..5931
                     /locus_tag="KRN00_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBH1828261.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            6118..8088
                     /gene="uvrB"
                     /locus_tag="KRN00_002401"
     CDS             6118..8088
                     /gene="uvrB"
                     /locus_tag="KRN00_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBH1828262.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            8107..10932
                     /gene="uvrA"
                     /locus_tag="KRN00_002402"
     CDS             8107..10932
                     /gene="uvrA"
                     /locus_tag="KRN00_002402"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1828263.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            11191..13008
                     /gene="uvrC"
                     /locus_tag="KRN00_002403"
     CDS             11191..13008
                     /gene="uvrC"
                     /locus_tag="KRN00_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBH1828264.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            13008..13937
                     /locus_tag="KRN00_002404"
     CDS             13008..13937
                     /locus_tag="KRN00_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBH1828265.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            14151..15947
                     /locus_tag="KRN00_002405"
     CDS             14151..15947
                     /locus_tag="KRN00_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBH1828266.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGLAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(16087..17868)
                     /locus_tag="KRN00_002406"
     CDS             complement(16087..17868)
                     /locus_tag="KRN00_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBH1828267.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(17891..19777)
                     /locus_tag="KRN00_002407"
     CDS             complement(17891..19777)
                     /locus_tag="KRN00_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBH1828268.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            complement(19794..20291)
                     /locus_tag="KRN00_002408"
     CDS             complement(19794..20291)
                     /locus_tag="KRN00_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBH1828269.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            complement(20609..22090)
                     /gene="cls"
                     /locus_tag="KRN00_002409"
     CDS             complement(20609..22090)
                     /gene="cls"
                     /locus_tag="KRN00_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBH1828270.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
BASE COUNT         8566 a         2975 c         3702 g         6986 t
ORIGIN      
        1 ggtaaattta taaaaattaa aaaattttta ttttttatgt ttaaaccttg taaatttggg
       61 acataatata attgtaaaac ttaatatagc aaaaataaat tactcaatct cccccactta
      121 aagacctcta tcccccatag aggtcttttt tactttcaaa tcaaattata taaaaaataa
      181 atagttttat atgactcttc ataaattaaa attacattgt gatagcaaac catgaatatg
      241 aaaaatatag aaaattatag ctaacataag ctgtatatca tcttaacctc agtatattta
      301 acaaaaaatg tttataattt aacctttatt ttaataagtt taccatatat tcactttgtc
      361 ttaatatatc ctttacaaat taagagtatt attaatctat aagtaaatcg tagaattaaa
      421 ttaaatattt tgggaggata aaaatggcag atataagact agaaaatgta acaaaatctt
      481 ataataaaaa aaatacagtt atagaaaatt taaatcttac tatagaagat ggttctttta
      541 cagtattggt aggcccaagt ggatgtggta aatctactac gttaagaatg attgcaggtc
      601 ttgaagatat aacttcaggt aggttgaaga ttgaagaaaa tgatgttaca aaaacggatg
      661 ctagtaaaag ggatatagct atggtatttc aaaattatgc attatatcca catatgactg
      721 ttagagaaaa catagaattt ggtcttaaaa acaaaaaagt agaaaaagaa aaaagagaaa
      781 aacttataac agaagttatt gatgtagtag gattgagaga atatttaaat gtgaaaccag
      841 gcaacttatc tggaggtcaa agacaaagag tggcacttgc tagagctatg gttaaaaatc
      901 caaaggtatt tttaatggat gaaccattgt caaatttaga tgctaaatta agaaatcaaa
      961 tgagaacaga attaatacaa ttacatcaaa aactaaagtc tacatttgtt tatgtaactc
     1021 atgaccaggt tgaggcaatg tcaatggcag ataagatagt tataatgaac aaaggaaaga
     1081 taatgcaaat aggttcccca aagaagatat atcaaaatcc taaaaattta tttgtagctc
     1141 aatttatagg gagtccttgt atgaacatac tagatataaa aaatgatatt aaatttggat
     1201 tcagaccaga aaaagcaaca ctagagagta taaacataga tggaaaaaat gatgatgtat
     1261 ttagtctatt tggaaaagtt gtaactaaag aagtgttggg aaatgaaact atatattgtt
     1321 tatctgttct taatagagag ataagagtca aaacagaaaa tgatatattt gatattggaa
     1381 gaactttaag aataagtgta ttagaaaaag atttatatta ttttgataaa aatggagaaa
     1441 gaatagaaga tgtaaaagta tgtaaaagta tgtattctaa aattaaagga gatatttatg
     1501 aaaaagcaat ttaataaagc atatttatat ataacacctg ctattatagg aactttattg
     1561 tttatagtct atccaataat taagacgata tctctaagct tcaaatctgg tagtcttctt
     1621 agttcaacct ttgaaaatgt aggcttaaac aattatacag aacttttaaa gaatccagag
     1681 tttatacaaa ctataacgaa cactgcaatt tatacttttt ttatggtgac tatatctata
     1741 tcactagcca tagtacttgc tgtttggcta aataaaaatt ctataataca caatttaacg
     1801 caaagtataa tctttacacc acatgtaatt tcactagtat ctgtagctgt attgtggctt
     1861 tggattatgg agccacaata tggcttttta aactggatac tatcgacatt acatttacca
     1921 acatcaaagt ggctttcaag tgaaagttca gctttaatgt cactaattct aataggaata
     1981 tggaagactc ttggatacaa tatcttaata gtgttatcag gtcttaaatc cataccaaac
     2041 tatatatatg aagcatctaa attagataat gcaaacaaaa taacgaattt ctttaaagtg
     2101 acattgccgc tattatcacc aacaatattt tttcttatga taacaacaac aactgcatct
     2161 tttcaagtat ttgatgagat aagtataatg acacaaggtg ggccagtggg ttcaactaac
     2221 atgttatctt attatatata tgagtctgga tttatatact atgacatagg acaagcgagt
     2281 gcagcgagta tgtttttgtt agctatagtt atgattgcta catatgctaa ctttagactc
     2341 ttatcaaaga aagttcatta tcaataaaga aaaagtagat attataaggt ttatccaaaa
     2401 ggaggagaca atggatatta tacaacctat caaaaaagac aaagttgata taaaaaaaat
     2461 agcatcaaaa tcaatagaaa tattaattct attactttta tctgcaatat ttatattccc
     2521 ttttatatgg atgctatcta catcctttaa aaatccacaa gaaatgatgc aattaccgcc
     2581 cactattata ccaaatgata tagtgttaga aaattatagt acagcatggc attcaggtcc
     2641 attttttaga tatttgctaa acagtgtatt tgtaacagga agtgttttaa ttgtacaatt
     2701 tttagttatg gttccagcag catatgcatt ttctaagatt aaatttaaag gtgaaaaaat
     2761 gctatttggg cttttgcttg taggacttat gattccacca caagtaactt ttctaccagt
     2821 ctatatgatg atgagtaagt ttggatttat aaatacttat gttccactta taattccatt
     2881 tatgacatct tcatttggga tatttctgct tagacagaat tttatgcaga tttcagatga
     2941 aattattgaa gcagctaaac tagataatgc ttctgactta aaaataatgt ttagaataat
     3001 ggttcctatg gcaaaaccag cagtaataac atttatatta tttaatttta tataccattg
     3061 gaataattat ttctggccct tagtaatgac aaatacagat gcaataagaa ctttaccaat
     3121 aggagttgcg ctccttaaat cttcagaagg aattactgca tggaatgtaa taatggcagg
     3181 aaatataatt ctaattttac caataattct tgtttatata tttgcgaata aaaaagtaaa
     3241 agaagctttt atgtattcag gaataaaata aaaaattaaa gactaaattt ggaggatgaa
     3301 aatgaagctt aaaagaaaat tagcaacagg attagcaata acattattat taggttcttt
     3361 agttgggtgt tcaaattcta atgatgcaaa tgcatctaaa ggagaaaaga ctgatagcaa
     3421 tattacgaag atagatttct gggctccttt aggtggaact aatggagaaa ctgctcaaaa
     3481 aatggttgac caatttaata gtgaacataa ggatgtacaa gtaaatatgt taaaacagaa
     3541 agattactat gaaaatgcaa caaaactaca ggcagcctta acatctaaag accaaccaga
     3601 tgtaacatta ttagaaataa ctcaaacagg tacattcgca tcagcaggtg ctttagtaga
     3661 tatgagtaaa tattttgata aaacatatca agaaagattc ttttctggtc ttttaacaaa
     3721 ttcatattat gaggataagt ttgttggtat gccatttaat agaagtacac caatattata
     3781 cataaataaa gatatggcaa ctaaagcagg tcttgaccct tcaggtccaa aatcatggga
     3841 agagcttaag gattatgcta gtaaaatgac aaataaatca gaagatactt atggttttga
     3901 aacgccaata gatatttggt tctatgaagc tatggtaatg caaagtggag gagaaataac
     3961 taatggtaaa aaagtagcat ttaataatga ggcaggacaa gcaccagtta agttctggca
     4021 agatatgatg aaagctggaa taatgaaaat gcctcctgga gaagattata atgcctggga
     4081 cgtagcaaaa caagattttg taaatggtaa agtaggtatg atatttacat caacagcaga
     4141 tttagcagga cttatgcaac aaacagaagg taagtttgaa atatcaacag cattcttacc
     4201 aaaaaatcaa aaatacgcaa ctcctacagg tggagctaat ctagttatgc ttgaaggtgg
     4261 aacagataaa gaaaaagaag caagtgcaga atttatagaa tggatgacac aaacagataa
     4321 aatcgttcag tttagttcat caacaggata cttaccaaca actgaagatg caacaaactc
     4381 agaaaagtta caaacattat ataaagaaaa acctcaatat aaggttgcaa ctgaccaatt
     4441 acaatatgct gttgcacttc caatgttaaa tggatacaag gaagcaactg ataagctaat
     4501 ggatgagatt aaaaaggggc ttactgattt aaatgcaaat ccaaaagatg tagtaagcaa
     4561 aggaacttct gcaatgcaag cagtaataga taaaacaaat aaataattat atagacttgt
     4621 aagttgatta aaagtattca ataatatata aatgaagagg taatgtaaat gacaaaggtt
     4681 atagtattat cagtagattc tttatttgaa aaagacttgg aatttgtaaa aaatctacca
     4741 aactttaaat ctatactaga aaattgctcc atagtaaaaa atataaattg tgtttatccc
     4801 actctgacat atccgtgtca tactagtatg gttacaggag tatatcctaa aaaacatggt
     4861 atatatcata atgaaaaatt tgacccaaat aaagaaaata aagactggta ctggtattca
     4921 aaggacataa aagcaaaaac tattatagat gtagcaaaag aaaataatct aactacctct
     4981 agtgtattat ggcctgtaat gggagcaaat ccaaatatag attataatat tgcagaaata
     5041 tgggctccta gtagagaaga tgacccaaga gaaacttttg aacgaagttc cagtaaggtt
     5101 ataatggacg gtatttacaa tagacattgt cattatatcg attggaaatt agaacccaac
     5161 atggatttat ttggagtaaa ctgttcagta gatataataa aggaatataa accagattta
     5221 atgctaatac atttagctac attggaccat acacgacaca attatggctt atttaatgac
     5281 gaagtagata aagcattaaa aatgaatgat aaatggttag gagatattat tcaggctaca
     5341 aaggatgcag gtacatacaa agatacaaat tttataatac ttggggacca tggtcatctt
     5401 agagttgata aagttataaa tccaaatgtc ttgcttaaat caaatggatt tataaaagtt
     5461 gaaaatggag aagttaagga ttttgatgcc tatgtaaatt cttctggaat atcagctcaa
     5521 ataatagtaa ataacttaga taggttaaca gaattaagag aactgcttga agaatttaaa
     5581 gaagaattat tcatagagaa tatttttacc aaagaggaag catctaacct tggtcttgaa
     5641 ggtgattttg aaatggtaat tgaaggtctt gaaggaattt catttggaaa tgatttcgaa
     5701 ggaagtatta taaaagattc agatataaaa gattacaagt ttgctgttgc gacacatggt
     5761 catttaccta ctaaaggtaa tagacctcca tttatagctt ttggaccaaa tattaaaggt
     5821 ggtgtggtta tagaagaagg agacctgaga gcacatgcag caactatatt aaaaatgttt
     5881 aatttaaaat tagatggagt tgaaaaagaa gcatttgatt ttattatgta agttgaataa
     5941 agtatttatt ttccatgaat tatagacttc tattgcaaag atagaagtct ttttttatgt
     6001 tttagattta agtaaaattt aaatgggtaa aatatttaaa ataacttaaa caattttata
     6061 aaggtatgat ataataatac atgtcaggaa ctaatgttcg aaaaaaggag tgatactatg
     6121 gattttaaaa taaaatcaga cttcaaacct acaggtgacc aaccagaagc tattaaatca
     6181 atagtggatt ctataaatag aaatgagaaa ttttcgacat tattaggtgt aacgggttca
     6241 ggaaaaacat tcacaatggc aaatatcatt caacaagtta agaaacctac cctaataatg
     6301 gctcataata aaactctagc agcacaactt tacagtgagt ttaaagaatt tttcccagac
     6361 aatgcagttg aatactttgt aagttactat gattattatc aaccagaagc atatgtagct
     6421 cacagtgaca cttatataga aaaagatgca agcataaatg atgaaataga taaacttcga
     6481 cattctgcta cagcatctat tttagagaga agagatacta taataatatc atctgtatct
     6541 tgtatatatg gacttggtga cccaaaagac tataaagaac ttatgttatc tataagacca
     6601 ggtatgcaaa gagacagaga tgatgtaata aaaaggttaa tagagataca atacgaaaga
     6661 aatgacataa actttacacg aggtaccttt agagttagag gagatatact agaaatattc
     6721 ccagctagta atgatgaaaa agcaataaga atagaatttt ttggtgatga ggtagataga
     6781 ataacagaaa ttgattatgt aacagggaag attgttggta ctagaaatca tgttgttata
     6841 ttcccagcat ctcactatgt aacaacgcca gaaagaattg aaaaggcaat tgtagaaata
     6901 gaaaacgagc ttcaagaaca aattaaattt ttcaaggaaa atgataggtt attagaagca
     6961 caaagaattg aacaaagaac taagtatgat atagaaatgt taaaggaaat aggattttgt
     7021 caggggatag agaactattc tagacatatt acaggaaggt cagaaggaga aagaccatat
     7081 actttaatgg atttcttccc agatgattat ttgataattg tagatgaggc acatgtcact
     7141 ataccacaag taagaggtat gtatgcagga gacaggtcta gaaaaacatc acttatagag
     7201 aatggtttta gattaccttc tgcacttgac aatagaccat taaattttca agaatttgaa
     7261 ggaaatataa atcaaatgtt gtttgtaagt gctacaccag gaccttatga aattcaacac
     7321 tcagagacaa tagcagaaca gataataaga ccaactggcc ttttagaccc aattgtagaa
     7381 gtaagaccta taaataatca aatagatgat ttggtaggag aaataactaa aactatagaa
     7441 aaaaatgaaa gagtgcttat aaccacttta actaaaaaaa tgagtgagga cttgactaac
     7501 tatcttaaag aaatagggat aaaagttaaa tatttacact cagatatagt tacattagaa
     7561 agaacagaaa taataagaga tttaagatta gggaagtttg atgtccttgt aggaataaac
     7621 ttacttagag aaggattgga tataccagaa gtttcactta tagcaatttt agatgcagac
     7681 aaagaaggtt tcttacgttc cgaaacagct ttaatacaga ctattggacg tgcagctaga
     7741 aatgaaaatg gaagagtaat tatgtatgca gacaggataa ctgactcaat gcaaaatgct
     7801 attgatgaaa caaagagaag aagagatata caaaatttat ataatgaaga gcacaatatc
     7861 attcctaaaa ctatacagaa aaatataaga gatagtatag aagctactaa ggttgcagag
     7921 gaagaagttg tatatggaat atctgataca gatgataaag acgaaataag agctaatata
     7981 gataaattaa aatcagagat gatggaagct gctcaaaact tacaatttga aagagcagca
     8041 gaacttagag ataaagtgaa acaattagaa gaaaaattgg aaaaatagaa aggtaaaaac
     8101 aacattatgg aagataaaat tataataaga ggagcaaaag aacataattt aaaaaatata
     8161 gatttagaat taccaagaga taaatttatt gtttttacag gtttgtcagg gtctgggaag
     8221 tcttctttgg catttgatac aatatatgca gaaggacaga gaagatatgt agaaagtcta
     8281 tctgcttatg caagacaatt tttaggtcag atggaaaagc caaatgtaga atatatagag
     8341 ggtttatcac cagctatctc aattgaccag aagactacct caaaaaaccc acgttctacg
     8401 gttggaacag taacagaaat atatgattat ttgagactat tatttgcaag agtaggagat
     8461 gtgtattgcc ctacatgtgg tgaaaaaata agtcagatga ctattcaaga aatagttgat
     8521 aaaatgctag attttccaga tagaacgaaa ttacaaattc tttcaccaat tgttagagga
     8581 caaaaaggta cacataaaaa agtctttgat aatatcaaaa aagaaggatt tgtaagagtt
     8641 agagttaatg gtgaaaacta tgaagttagt gatgatataa tcttaaataa aaatcaaaaa
     8701 cataatatag aagttgtagt ggacagaata gtaattaaag atggaataga atcaagacta
     8761 gcagattcaa ttgaaactgc agttaagcta tctgatggtc ttgtaatagc ccaaataata
     8821 gatggagaag aaattctttt ttcaactaaa tttgcatgcc cagaacatgg aattggcata
     8881 gaagaattat ctccaagaat gttttcattt aatgctccct ttggtgcttg tgatgtttgt
     8941 aatggtcttg gggaaagtaa agaagttgac ccagaattag tagtaccaaa caaagattta
     9001 tcaataaaac aaggtgcagt ggcagcatgg ggttcaacag gtgttaatga tgacacttat
     9061 tacagtaaaa tgataaaaag tttagcagag cattttaatg tatctttgac aacaccgttt
     9121 aaagatttac cagatgattt tgtggaggaa ttactttatg gtaaagataa tataattgta
     9181 gagtttactt atgagtcaaa atttggagga actagaaatt ataaatcata ctttgaaggt
     9241 gtaatagtaa acttagagag aagatataga gaaactaatt cagattacat gagagataag
     9301 attgaagaat acatggcaga gagaccatgt ccaaagtgta aagggatgag acttaaaaag
     9361 gaagttttat ctgttttagt tgatggaaaa aatataatgg aagttacaaa cttatctgta
     9421 aatgaattga ttgactttat ggaaaatata aatcttacag aaaaacagag atttatagct
     9481 catgagatta taaaagagat aaaaggaaga gctatgttct taagagatgt aggtcttgat
     9541 tatttaaatt tatcaagaaa agctggaact ttatcaggag gagaagcgca acgtataaga
     9601 ttagctactc aaataggttc tgcattggtt ggagttttat atgtacttga tgagccaagt
     9661 atagggcttc accaaagaga taatgatagg cttataacta ctcttagaca tctaacagat
     9721 ttaggaaata ccttaatcgt tgtagagcat gatgaagaca caatgagaga agctgattat
     9781 gttatagaca ttggtccagg tgcaggtata catggtggtg aaatagttgc acagggtact
     9841 ttagatgaaa taattgaaaa tgagaactca ataacgggtc aatatttaag tggtaaaaaa
     9901 caaatattgc ttcctgagac tactagagaa ggaaatggaa gttttataga aatagttaaa
     9961 gcatcagaaa ataatctgaa aaatattgat gtaaagttcc cattaggtaa gtttacatgc
    10021 ataacaggtg tttcaggttc tggaaaaagt acattaataa acgatatact ttacaaaggt
    10081 gttgcaagta aagtgaatag acttaagcaa agagctggta agcataagga gataaaagga
    10141 attgaaagta tagataaagt tataaatata gaccaaagtc ctattggaag aacacctcgt
    10201 tcaaatcctg ctacttatac aggtgtattt gattttataa gagatatttt tgcatctact
    10261 aatgaagcta aagcaagagg ttataaaaaa ggtagattta gttttaatgt aaaaggtggt
    10321 agatgtgaag cttgtaaggg tgatggaata ataaaaatag aaatgcattt cttaccagat
    10381 gtatatgttc cttgtgaaat ttgtaaaggt gaaagataca atagagaaac attgcaagta
    10441 aaatacaaag ataaaactat atctgatata ttagatatga atgtggaaga agctgttgag
    10501 tttttcgaaa atataccaaa tataaaaaga aaattagaaa ctttaatgga tgtaggactt
    10561 tcatatatta aattaggaca gccttcaact caattatcag gaggagaagc acaacgtata
    10621 aaattagctg ctgaacttag taaaagacca acaggaaaga ctttgtatat attagatgaa
    10681 cctactactg gacttcatat ggcagatgta gacaagctaa tccaagtatt acaaagacta
    10741 gcagatacag gaaatacaat tatagtcata gaacataatt tagatgttat aaagacttgt
    10801 gattatgtaa tagacttagg accagaaggc ggagataagg gtggaactat agttgcaact
    10861 ggaacaccaa aagaagtatc taaagttgat ggttcttata caggtcaatt cttaaagaaa
    10921 tatttttctt aagttatata aattgtgaaa aattttagag cagatatacg ataaactgtt
    10981 ttgttataag taaattagtc aaatataagt tgtaaatagt aatacaaagt aaagtccata
    11041 ttactcttca tggttaaaat tgttttcaaa tcaattatag aagggaatat gggctttaac
    11101 ttgtttaaag cactggaaat tgtataactt tttaaaattc atattttagg gtataatttt
    11161 agtataaaat ttaatgtttt ggagggcgag atgtttgata tacaagagca tttaaaaaaa
    11221 ttaccttctg agcccggagt atatttaatg aaagacaaat acgaccatat aatatatgtg
    11281 ggaaaagcca tatctctaaa aaatagggta aggcagtatt ttcaatcttc aaaaaaccat
    11341 acatctaaag taaaatctat ggttaagaat atatataagt ttgagtatat tataacggat
    11401 tcagagttag aggcattaat acttgaatgt aatttaataa aaagatacag accaaagtat
    11461 aatgtagtgc ttagagatga taaaacttat ccatatataa aagtaactac gaatgaagat
    11521 tatccaagaa tcttaaaagt tagaagagtt cttaaagata aggcaaagta ttttgggccc
    11581 tataccaata taactgctgt gaatgatacc ttggagctta taagtagtac gtatccaata
    11641 agaagctgta aaatagatat agataaagca ataaagaata agacaagacc ttgtttaaat
    11701 ctacacataa ataaatgttt aggaccttgt acaggaaatg tttctaaaga agagtatgga
    11761 aaaatgatag aagagattat aatgtgttta tctggtaaag aagaaaaatt gatggaactt
    11821 ttaaaggaaa aaatgaatga gagttctatg aactttagat ttgaagaggc tgctgtatat
    11881 agggataaga taaagagcct tgaagagatg atacagaaac aaaaaataga tgctactgta
    11941 agtgacttaa accaagatgt ggttgcaatg gcaagagctc ataatgaagc ttgtgtccag
    12001 gtatttttta taagaaatgg taagattgta ggtagggaac attttatatt agaaggggta
    12061 atggatagtc caagagcttc tatattaagt tcatttgtaa aacaatttta taatgaacaa
    12121 gagtatatac ctaaagaatt aattatagaa gatgagatag aagatagttc tatattagaa
    12181 gaatggctgt catctaaaaa ggggcaaaaa gtaacaataa gagttcctca aaagggagag
    12241 aagaaaagct tagttgaaat ggttaggaaa aatgctgtag aatatcttga aaaattttct
    12301 gatatgaata aaagaaaata tgaaaaaagt attggagcat tggaagaatt aaagcaaata
    12361 ttaaatctag aaaagttgcc aataagaata gaggcttatg atatatcaaa tatacaaggt
    12421 gtagattcga ttggttctat ggtagtgtat acgaatgcta aaaaagataa gaaggaatat
    12481 aggagatata aaataaagac agttattgga cctaatgatt atgattctat ggctgaaatt
    12541 gtagatagaa gattaaaaca tggaaattta cctgacttga tattgttgga tggtggaaaa
    12601 ggacaagtta gtgcagtaaa aaaagtacta gaactcaatg atgtagatat acctctttgg
    12661 ggaatgtaca aagatgataa gcatagaact aaaggattga tatgcaaaga aaaagaaata
    12721 gaactagata aaacaactaa tttatataga tttattgcta gtatacaaga agaagttcat
    12781 aattatgcaa taacatatca tagaagtcta agaaataaag ctttgacaaa atctatctta
    12841 gatgatatac aaggaatagg tgaaaaaaga aagaaatcat tattaaatca ctttaaagat
    12901 gtagatgcta taaaaaaagc tactatggaa gaacttttag aagtggatgg aatgaataaa
    12961 agcattgcag ataatgttta taattttttt agaaaggaag aaaattaatg gaaactagca
    13021 ataaagtatc aataagagag ataataaaag agttgaagtt aaaagtagta tacatgcctg
    13081 atgatgtaga ttattatgtc tactctcaag atataaatag accaggatta cagtttgcag
    13141 gatattttga ttattttgca tatgaaagaa tacaaatagt tggaaagaca gaatataatt
    13201 tttttggatt aatggatagt catattcgag aagaagtact agatagattt ttctcatatg
    13261 aaataccagc gttaataatt tctagagact tggaaatcaa gccagatgta attgaaaagg
    13321 ctaaaaaata taaaagaata cttttgagca caaatagaaa taccactaga cttataaata
    13381 gactgtcaaa ctatttggat aataagttag caccacatac aacaattcac ggggtgctag
    13441 tagatattta tggtataggt gtactgataa aaggtgaaag tagtatagga aagtcggaaa
    13501 cagcattaga attgattcaa aggggtaata gattagttgc agatgatgct gtagaaataa
    13561 gaaaattaga tgaaagtatg cttgtgggtc agtcacctga actaataaga cattttcttg
    13621 agataagagg aataggaata atagatgtta gaagtttata tggagtaggg gcaatcaaaa
    13681 attctaaaat gatagattta gtagttcatt tagaagcttg ggatgaaact aagtattatg
    13741 atagactagg actggataaa gaatatgaag aaatacttgg tgttaatgta gagaaattag
    13801 ttgtacctgt taaacctgga agaaatactg ctatgatatt agaagtagca gcaatgaatt
    13861 ttagacaaag aggaatggga tacgatgcag ctcaagaatt tactaaaaaa ttatcaaaat
    13921 taatcgatac taagtagtac tgaataatag tgaactacac atcatttaat taaatattga
    13981 ttaggattat atcctacacc ttataaatta aaatcaagtt gtatatatat gatgtttatt
    14041 aataagatat attatataag gataatttaa agtacagtgt tagattataa taatactaga
    14101 ttaattttat atttgagttt cattatataa caagaaagtt ggaatttttt atgggaatag
    14161 aatattttag taaactttta gaaagtagta ctgaaaaaga attgctctta agtaaaaagt
    14221 caaataacat aagtacagca agattaatat cttttttgat agtgatagca gggcttgcta
    14281 ttggatttta caataaaaat atagtaggta tttttgttgg agttttatca ataataatat
    14341 ttatagcact cttagttatt catagtaaag taaaagaaga agaaacatat tttaaaagca
    14401 agagcgaagt attaaataag tatattaaga gatttggaga tggttggaag gaatttaaaa
    14461 tagatggaaa agaatactta aaagatgaaa actcgcaagc aaaagattta gacttatttg
    14521 gaagagcatc attgtatcaa tatatctgtg tagctaatac atcttatggg aaaaattttt
    14581 tagccaaata tttgtggaat gaaaatccag atgagaatgt aatcttagaa agacagagag
    14641 ctataaaaga acttttatca aaagatgatt tttctattca tattcaaaca ctcagtaata
    14701 taattggtaa agagcaaaaa aacaattcag atagtagtat agaatcgttt atagaatatg
    14761 gagaaaataa gaatgtgtat ataccaaaat ggatgcatat ttttacttgg ggtttaccaa
    14821 ctgcaacaat cttatctttt atattttgta tgttaggatt tttacctgtt ttacctgttt
    14881 ttttactttt tataatccag ttagggttta gtggttttgg atatccaaga cttatgcaaa
    14941 ctcttgctcc attattttca tttagtagaa gtatacaagt atatgaaaaa atgtttgagg
    15001 ttttagaaaa agagacgttt gagagtgcat atttgaaaga attacaagat aaactttcta
    15061 agggaagtgg agtttcaaga ggtgttaaac aattaaattc aataggaaat gctgtaaacc
    15121 taaggtataa tcagatacta tatataattg cctgtggtgt tttgatgtgg aactatcatt
    15181 gtgcagaagc tttggagcga tggaaaggta tatatggaaa tcaaattaga gattggtttg
    15241 aatctattgg agaatttgaa gctctaataa gtttaacagt tgtttctcat gtaaaggaaa
    15301 atacatgttt tccagtaata aaatatgaag atactccaag attgaaagtt gaagaggtat
    15361 accacccatt aatagcagaa aaaagtgtca tagcaaattc gatacaatta aattctcaga
    15421 cttgtattat cacaggttca aatatgtctg gaaagacaac atttttaaga agtatcggtg
    15481 taaacttagt gctggcatat gcaggtgctc cagtatgcgc taagagtttt gatgcaacct
    15541 gtatggctat atttacttct atgagaatac aagatgatgt aagtcaagga atatcaactt
    15601 tctatgctga gattcttaga ataaaatcaa tgattcaata tagtttaaaa gaactgccaa
    15661 tgttggttct agtagatgaa atttttaagg gaactaactc tgctgataga attattggag
    15721 caagtgaggc ggtaaagaaa ttatcaaaac cctgggttat aagtatggtg acaacacatg
    15781 actttgagct atgtgacctt tcaggtagtg gagatgttga agttgtaaac tatcatttct
    15841 cagagtacta tgtagacgat aaaattcatt ttgactataa gataaaagat ggaagatgta
    15901 aaactacaaa tgcaaaacaa cttatgagaa tggcaggtat tctttaatta atagataggt
    15961 taattaaaga ataagtctat ttagaaatat aatttaattt gtgaaattaa taaggattgt
    16021 cttaaattac gtaaaagtat tttaagacaa tcctttttta agaataaatt ttatactttg
    16081 ttatgactac ttagcttctt cacaagcaca ttcttgtgga cactctccat agacacaact
    16141 cttatcaaag taatgagtat gaaggtattt atgagctaca tcactatttg gttctccaaa
    16201 gaagtcttta taaatagctt gtaaatcagg attctcatga gatttacgaa tagccttatt
    16261 tctatctatt tcatataacg catttgcacg tctatcaact atttcagtat taccatggtg
    16321 ataaggttga ccagcacctc caacacatcc accaggacat gccataactt ctatgatatg
    16381 gtatttacat tctccacttc tgaccttatc cataatcttt ctagcgtttt taagtgtatt
    16441 tacaatacac acattaactg tagttccatc aacatctata cttgcttccc taattccttt
    16501 aagacctcta acattagtga agtttacatt atctaaagtc ttattagtta tcttctcata
    16561 tgaagtacgt agggcagctt ctaaaactcc accacttgct ccaaatatag atgcagcacc
    16621 tgtagatttt cctagaggat tatcaaaatc ttggtcttga agattaggta aatcgatagc
    16681 agcttctttt atcatcttag ctaactctct agtagttata gaaaggtcaa catctagtat
    16741 tccagattca cttaattctt ctcttgaagc ttcatatttt ttagctacac aaggcattac
    16801 agatacaaca taaagttctt caggattgat tcctaatatt ttaggtgcat agtagttttt
    16861 agctatagaa ccaaacatac cttgaggaga cttacagcta gatgctaagt ttaacttgtc
    16921 tggatagttg tgctctaaga agtttaccca tgcaggacaa cagcttgtta atataggaag
    16981 attttcacct ttttggattc tttctataaa ttcagtagct tcttccatta tagtaaaatc
    17041 tgcaccaaag tttgtatcaa atacatgttc aaatccaagt gcttttaaag cagctaccat
    17101 ttttcctgta gagattgacc ctggttctaa tccaaactct tcaccaatag caactcttac
    17161 ggcaggagca acttgcacta ctatagtctt ttctttttta tttaaaacat cccaaagttt
    17221 aggtacatta tctacttctg ttaatgctcc agttggacag acagatatac attgaccaca
    17281 gaatgtacac tctgtttcaa ccatatcaga gttaaagaat gtactaacta aagtattaaa
    17341 tccacgatta actccagata atgctcctac tgtttgtatg tcattacata cagtctcaca
    17401 tcttctacat aatatacact tagaatggtc tttaactaaa gatttagtag aagtatcttt
    17461 acctgcaaaa gatttagaac cttgatatct tatttttctt actcctaaat cagcagctat
    17521 agtctgtaat tcacaatctc catttttttc acagacaaaa caatcttgtg gatggtctga
    17581 taacaataat tcaacaatag ttctacgagc atttaatgct ttagcactat tagtctgaac
    17641 tttcatacct tcctttataa ctgttccaca agctggaact aatcctctct ctgtctcaac
    17701 catacaaaca cgacaagaag cacaagtgtc aagcttatct atttcattca tatgtaaatg
    17761 acaaaggttg tgtattttta tatttattaa tttcgcagca tctaagatag aagttccact
    17821 aggtgctgaa acgtgtttgc cattaatagt taaattaact aaactcattg ttattcctcc
    17881 tccaaataag ttatttcttg attatagcgt taaatgtaca attatctata caagcaccac
    17941 attttagaca cttagaagta tctattgtat gttgttcctt aacagaacct gttatacaac
    18001 cagcaggaca cactctagaa cattttgtac aacccttaca gtcatctgtt ataaagtaag
    18061 aaagtaagtt ctgacattta ccagcaggac atttcttatc tacaacatga gctatatact
    18121 catctttgaa atattgaaga gtacttaaaa cagggtttgg agcagcttta ccaagaccac
    18181 ataatgaagc agtttgtata gtttcagcaa ggttttctag gtcatctaaa tcttgtagag
    18241 taccattacc ttctgtaatt ttagttaata tttctaataa tcttgtagta cctatacgac
    18301 aaggtgtaca tttaccacaa gattcttcaa cagtaaactc aaggaagaac ttggctatat
    18361 ctaccataca gtcagattca tcaagaacaa gcataccacc agagcccatc attgaaccga
    18421 tagaacttaa tgaaccaaag tctataggag tgtctaaatg ttcagttggt atacatccac
    18481 cagatggtcc acctgtttga acagccttaa atttcttacc ttcagggatt cccccaccaa
    18541 tttcaaatac aatatctctt aaagtagtac ccattggaac ttcaacaagt cctacatttt
    18601 ctacttttcc accaagagca aagactttag taccactaga atcttcagta cctaagttgg
    18661 caaaccaatc tccaccctta agtataattg caggtatgtt agcaaaagtc tcaacgttat
    18721 ttaagcaagt aggagatttc catagaccac tcttagaaga actataagtt ttcattctag
    18781 gttcaccacg tctaccttca attgaatgca ttagcgctgt accttcacca caaacgaaag
    18841 cacctgcacc atattttaat tctaatttaa agttaaatcc agtgcctaag atattttcgc
    18901 caagtaaacc gtatttttca gcttgagcta tggctacttt taatctttct atagattttg
    18961 gatattctgc tcttatgtat atgtatcctg tatcagaacc tatagcgtat ccacatattg
    19021 ccatagcttc tagtacacta tgagggtcac cttcaagtac agatctatcc ataaatgcac
    19081 ctgggtcacc ttcatcagca ttacatacaa caaacttttt atctgttgga ccagctggat
    19141 tttttgaagc agcttcccat ttagagccag tagggaaacc tgcaccacct ctaccacgaa
    19201 ggccagaagt ttttacctct gcaataactt cttgaggagt aagagaagtt aaacatttgc
    19261 ctagagctaa ataaccatca ttggcaatat attcttctat actatctggg tctataagac
    19321 cacaattttt taaagctata cgtaactgtt ttttgtagaa agacatttct tcttgttctt
    19381 caactttttt acttaaagat tcttcctcat ataataattc ctcgacaact gtatttctaa
    19441 ttaagtggct ttgaactatc ttttcagcat cagatggctc aacttttacg tagaaaacgt
    19501 tatcaggata aacttttaca ataggacctt gagcacagaa accaaaacaa cctgtcaaac
    19561 gaacactaac tttatcttgg attcctgatt tctttatttc attttctaat tcactaacta
    19621 tttctagact gtttgaagat gtacatccag tatcacaaca aacaagtaat tctcttctta
    19681 atacattttc cttagaataa ttttttctta agctaagatt aggtttcagc tcatcagcta
    19741 aaacttttaa ttcatcaaat gaatttactt tacgcattat ttattcaccc ctcttaacaa
    19801 ttcaattcta attctctata agtatctaat atttcgctta cttggtcagg tttcacttta
    19861 ccataaactt taccatttac agtaacaact ggagctaaac cacatgcccc caaacatctt
    19921 aaaccttcta aagaaaattt aaaatcacta gtagtttctc caacttttat gccaagctgt
    19981 ttttcaaaag cacttaagat tttgtcagca ccttttacaa aacatacagt tcctagacag
    20041 acactgattt tatacttacc tacaggttct gtagtaaaat aagaatagaa tgtaacaacc
    20101 ccatatacct ttgcaggagc tactccaagt tttctagcaa catgaagttg aacttctttt
    20161 ggaagatatc caaatatacc ttgggcttca tgtagaactt gtattaacgc accttccttt
    20221 gttgcaagag agtcaataaa tatatctagt tcgtcaaata attgcttgtt gtgtgaaata
    20281 aaatcgcaca taacaaatcc cccttttctt tttaaagtta ttatttttca taaaataatt
    20341 aaccatgagt tgaccccaac attatgtggg tgaacaaaac caaaacaata aagaaagaat
    20401 aatatacaac aatttcttta tttataaaaa caatgcaaaa aagttaccta ttaaaaataa
    20461 aaactatact agtctattat aatataaaat aattcagaat agttaaaaaa aataaaaaaa
    20521 atgagctaaa ttcaataaaa aaaaaataat acatataaaa aactttaaaa aataaaccaa
    20581 aatgtaaaat ttttataaaa taaaagattt ataaaactgc tgataatagt cttgaaattg
    20641 attccttgat ttttatataa gtagacctag aattatatat atctaatgtt atttccttag
    20701 aatttaaaat atcattttca aatataattc tttgttccaa tgcttttttt gaagagtaca
    20761 taaatgcatt aacttcgaaa ttaagctcaa aacttctgat atccatatta gctgttccta
    20821 tagagcatat agagtcatct ataactattg tcttagcatg taaaaatgca ttttgaccat
    20881 aagtatagat tttagctcca aactttaaaa gttctccagc atatgaatat gatgcccagt
    20941 atacaaaggg atggtcaggt ttagaaggaa tcatcactct cacatcaaca ccagataaac
    21001 aggctatttt taaagtatct ataaaagttg agtcaagtat taaataagga ctctgtatgt
    21061 atatatactt tctagctttc tgaatcattt taaggtaacc atatttaatc tcatcaagtt
    21121 ctgatatatc tggaccactt gatactatct gaatcccaat attttcagaa ggatgattag
    21181 aatttgtatc ttcttctata aagtattttt ctaaatctaa gtcttcttta gttgtatatc
    21241 tccaatcaag gatgaatctc atatttaggt caattacgca atcaccagta agcttagtat
    21301 gtgtatctct ccatagacca aattttggat ttctacctaa atattcatca ccaacattat
    21361 atccacctac aaatcctacc ttaccatcaa tgacaacaat ttttcggtga tttctatagt
    21421 ttaagttaaa gtttacaatt ttcaagaatg atgggaagaa gcttccaact ttaacaccac
    21481 tttctttaag tctggaaagt gtactatttt ttagtgttct accaccaact gcatcaaata
    21541 aaagtcttac ttcaacacct tctttagctt tgtctataag aatgtctatt atttcagttc
    21601 cgattttgtc atctttgaaa atgtaaaatt gtatgtttat atatttttta gcttttttaa
    21661 gttcttcaag aagactgtta aaaaattgac tagattcagc ataaatccac acatcgttat
    21721 tattggtata atgagcatta tttgaattag ccaatgcata aatcatatcc ttatgttgat
    21781 gtatatctga atcaatttca gatgtagatt ggagtttaac ctgagtatct agtatattac
    21841 ttttgattat cttatcatcc ttttctttca atctaaacat attgtttttt gaaatatttc
    21901 tgccaaaagc tatataaagt atgaatccaa gagcaggaat caatactaat ataagaagcc
    21961 atgttaaagt tgtatttatg tttctttttt ctctaaagat aaggtttagt ataaccatga
    22021 aattaattat atatattgta gtaactgcta tttcatatat tgacatttcg aaaaatgata
    22081 tatcaaacat aaaattccct ccttcaaata tttattaaaa taagtaatta tatataataa
    22141 cacaaacata tatctattat atataatacc tcaataatta aaaagtaaaa taaataatca
    22201 aaaggtaaat ttttcaaatt caatataaa
//
LOCUS       DAEQAF010000059        22153 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.061, whole genome shotgun sequence.
ACCESSION   DAEQAF010000059 DAEQAF010000000
VERSION     DAEQAF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22153
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.061"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            53..388
                     /locus_tag="KRN00_002410"
     CDS             53..388
                     /locus_tag="KRN00_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1828271.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
     gene            525..1802
                     /locus_tag="KRN00_002411"
     CDS             525..1802
                     /locus_tag="KRN00_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBH1828272.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKEQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            1923..3311
                     /locus_tag="KRN00_002412"
     CDS             1923..3311
                     /locus_tag="KRN00_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1828273.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            3682..4395
                     /locus_tag="KRN00_002413"
     CDS             3682..4395
                     /locus_tag="KRN00_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBH1828274.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVALSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            4513..5382
                     /locus_tag="KRN00_002414"
     CDS             4513..5382
                     /locus_tag="KRN00_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBH1828275.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANVNLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKDLVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NDIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSIKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(5537..6682)
                     /locus_tag="KRN00_002415"
     CDS             complement(5537..6682)
                     /locus_tag="KRN00_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBH1828276.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFRYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(7016..7792)
                     /locus_tag="KRN00_002416"
     CDS             complement(7016..7792)
                     /locus_tag="KRN00_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH1828277.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            8374..9348
                     /locus_tag="KRN00_002417"
     CDS             8374..9348
                     /locus_tag="KRN00_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBH1828278.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            9446..9751
                     /locus_tag="KRN00_002418"
     CDS             9446..9751
                     /locus_tag="KRN00_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1828279.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            9907..11067
                     /locus_tag="KRN00_002419"
     CDS             9907..11067
                     /locus_tag="KRN00_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBH1828280.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            11117..12019
                     /locus_tag="KRN00_002420"
     CDS             11117..12019
                     /locus_tag="KRN00_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBH1828281.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            12099..12992
                     /locus_tag="KRN00_002421"
     CDS             12099..12992
                     /locus_tag="KRN00_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBH1828282.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     regulatory      13045..13226
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            13454..14584
                     /locus_tag="KRN00_002422"
     CDS             13454..14584
                     /locus_tag="KRN00_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1828283.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     gene            14656..15681
                     /locus_tag="KRN00_002423"
     CDS             14656..15681
                     /locus_tag="KRN00_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBH1828284.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            15684..16880
                     /locus_tag="KRN00_002424"
     CDS             15684..16880
                     /locus_tag="KRN00_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828285.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIANIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(17008..17733)
                     /locus_tag="KRN00_002425"
     CDS             complement(17008..17733)
                     /locus_tag="KRN00_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1828286.1"
                     /translation="MKTISKQKLEKTLEKHYLWLKNNNAGEKADLKELRLENIDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            18211..20310
                     /gene="nrdE"
                     /locus_tag="KRN00_002426"
     CDS             18211..20310
                     /gene="nrdE"
                     /locus_tag="KRN00_002426"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBH1828287.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGNKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            20323..21294
                     /gene="nrdF"
                     /locus_tag="KRN00_002427"
     CDS             20323..21294
                     /gene="nrdF"
                     /locus_tag="KRN00_002427"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBH1828288.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            21370..21996
                     /locus_tag="KRN00_002428"
     CDS             21370..21996
                     /locus_tag="KRN00_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1828289.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
BASE COUNT         8583 a         2441 c         3891 g         7238 t
ORIGIN      
        1 attgctataa aagtttgttt aataaattaa ataaagaaaa gaggagaata aaatgtacaa
       61 catagatgat atgatatata attgtccagt agaagcttta tcaaatattt taggtaaaaa
      121 atgggtggct ataattatat ggaaaataca agaagataaa aaacgatttg gagagctaca
      181 aagagctata ccagactgta gtaagaaaat gttagttcaa caactagatt ttttaattga
      241 acaggggatt atagtcaacc aaaaaaagtt ggttaataat gttgtagagt caacatattt
      301 tttaagtgaa tcaggattac gattgcttcc tgtcatggaa aaaatgatta tgtggagcaa
      361 taaaaattta aattgtgata aatactaaaa tttactctgt aagtaatgaa aatttaatta
      421 agctatgagt agaaaaatgt attaaaatta cataattttt tagttagatt ttaatttaga
      481 aatgggattg taatattgga aataaaataa ggaggaattt taatttgcaa aatgtaaatt
      541 tatttttagt atttatagaa ggtatagtat cattcttttc accatgtata ctgccaattt
      601 tgcctattta tttgagtata ttgtcaaata gtagtgtaga aaatttaaaa gaaggaaaga
      661 cgagttttat aggaagttct ttatttaaaa atactatatt ttttgctctt ggaatctcaa
      721 caacattctt tatattgggt tcatcagtaa aagtattgag tatgtttttt aatgaaaata
      781 aagatttaat aatgtttatt ggtgggatta taattattat catgggatta ttttacatgg
      841 gaataattaa atcttcaata ttgaatagag aaaaaagatt taatgttaag tttaaagaaa
      901 tgaaagcaat aacagctttt atattaggtt ttacatttag ttttggatgg acaccttgta
      961 ttggtccaat attggcatct gtattagtca tggtttcaag ttcaagtaat catcttagtg
     1021 ccaatctttt aatagcagta tatactattg gttttatttt gccattcata attacagcta
     1081 tgttttacag taaactattt aaaactatag ataagataaa atctaacatg gaaattatta
     1141 aaaaaatagg tgggattata cttatagtat caggaatatt aatgatggta aatggatttg
     1201 gaagtataag caaacacttt aatacgtcac aaaatagtaa aattgaaagc aagcaagaag
     1261 aaaataagcg agaaaattct actgataaag aagaaaattc tgatggtaat gatagtcaaa
     1321 aagactctaa taatgacaat aatgataaag ggtctaatga tgaagataga ataaagtcta
     1381 ttgattttac tttaacagat cagtatggta aaacacataa attaagtgat tatgaaggca
     1441 aagttgtatt cttaaatttc tgggctacat ggtgtcctcc atgtaaagaa gaaatgcctt
     1501 atatagaaca actgtataaa gactataata aaaataatga tgatgtagta attttaggag
     1561 tagcttcacc taatttaggt agagaaggtt caagggaaca tgtagttaac ttcttaaaag
     1621 aacaaggtta tacattccct gttgtacttg atgaagatgg agcattagca tatcaatatg
     1681 gaattaatgc ttttccaact acatttataa ttgacaagga aggatatgta actcagtata
     1741 ttccaggagc tatggataag gcaactatgg catcatttat tgaaaatcag agaaataaat
     1801 aaaagtattt aagtataagt ttataaatca atttaaggtt acaaaaaagt gcctaattgt
     1861 accacctaaa taatcttgtt atagtaaaag tataaacaat acaagaaagg gttgaatttt
     1921 atatgaaaaa aacatttgat gctataataa taggatttgg aaaaggtgga aaaacattag
     1981 caggggattt ggcaaacagg ggattaaaag tagctttaat agaaaagtca aacaagatgt
     2041 atggtggaac atgtgtaaat gtggcatgta taccaacaaa aagcttagaa aattcagcaa
     2101 acagcgtaaa aacaaagaat ataaattctt gggatgaagt acaagctgaa tatgagaaag
     2161 ctatagataa aaaagaaact ttaattacaa aactcagaga agctaactat aataaattaa
     2221 attcaaatga gaatgtaact atattcacag gaatgggaac tttcattgat gaaaaaacag
     2281 ttcaagtcaa aactgaaaat gaaatttatg agttagtagc agataatata tttattaata
     2341 ctggttcaag accatttata cctaatatta agggaattga aaataagaat atagtatatg
     2401 atagtgagtc tcttatgaat ctaagagttt tacctaaaaa aatgacaatt ataggagctg
     2461 gatttatagg tttagaattt gctggtattt atagttcatt tggagcagaa gttacaatat
     2521 taaactctaa taatggcatt ttaccaaatg aagatgttga ggattcagaa gaaataataa
     2581 aattacttgc aaagagaaat gtaaaaattg ttaataatgc aaatataaaa gagattaaag
     2641 aagtttctga attagcaata gtagaatatg aagtagatgg taaatctaaa gaattaacaa
     2701 gtaatatgat acttgtagct acaggaagaa aagcaaacac tgaagggcta gggctagaaa
     2761 atgcaggtat agaattaaat gaaagaggat ttattaaagt ctcagaaact cttaagacta
     2821 ataaagagca tatatgggct ataggagata taaatggagg tccacaattt acttatattt
     2881 cattggatga ttatcgcata gttattaatc agttatttgg agataagact agaacaacta
     2941 atgatagaaa gaatatccca aattctatat ttataagtcc agcattttca agagttggtc
     3001 ttaatgttaa gcaagctaaa gaaaagggat atgaagtatt agtggcaaag atgccagtag
     3061 aagcaattcc aagagctaaa cagattggca aggcagatgg gtttataaaa atagtgatag
     3121 ataaaaaatc caataagata cttggagcta gtatgatatg tgaaaattca agtgagatta
     3181 tccatcttat tcaattagct gtagatttag aagtagagta tacatattta agagaccgtg
     3241 tttatgcaca tccaactatg acagaagctc ttaatgatat tctatctcct aatatgataa
     3301 aagaagtata acataagttt aatatataaa cctaaaatta tcattataag taggttttag
     3361 aaagaggcta tctcaaaaaa tagagataag tctctttttt actgtttaaa taataaaaat
     3421 atatttgatt ttataaaaga agattatttt atgagctaaa aagtttattt agaaacacta
     3481 cctatttatg ttataaagtt ataaatataa tatagaatct attattctgt attattaagt
     3541 ggggttaagc gttataatta attataaata ttgaataatc taaatggata agataatggt
     3601 attaaaaatt atcttaaaag gtgaaataat ctgtatttaa tgtagtacag ttatatcttt
     3661 aaagcaaggt ggtgaaatga tataaataag atatctaaaa gagggtttga tgatagtgat
     3721 aaaagatggt tttcaagtaa agaattaaca agacttataa aggctaaaga agaaatagaa
     3781 tggttattaa atagggatta caaaatagac ccagtcgtta cttttgttgg tgatagatat
     3841 cagttttcta taagacaaag agatgcatta aaaagggcag tctgtactga tgaaaaaaat
     3901 attataagac aatcaaaaag gctttctcta gataaaatca aagaagatac cgtaaatata
     3961 gatggcttta atttgataat atccatagag gtagcattat ctggtggtac tctagtaata
     4021 ggaagtgatg gcaatataag agatttagca ggtcttaggg gaacctataa gattatagat
     4081 aaaacagaag aagctttgaa tctgataggt aaatttttta ataaatacaa tgcacagaat
     4141 cttaaatttt atttagatgc tccagtttct aattcaggaa atttaaagta taggatatta
     4201 gagcatgcca aaacttgggg aattgaaact gaagtagaat tagtaaaaaa tgcagatgtt
     4261 gtattggaaa aattagatag agtagttagt agtgatgcag tcatagttga caagtgtata
     4321 agttatttta atgtggctag aggtataatt gaagagtata ttaaggaatg taatatcata
     4381 aatttaaata aatagataaa tataggtgag aatatataag tatatgtagc aatattatta
     4441 gtaatacaag taaagtttga aaataggaga acgaatacat atcgaatttc ataaaatgtt
     4501 gtaaaaagac atatgagagg atggatatgt gtgaaattaa ctaaactaaa tattaaaaaa
     4561 tatagagcac ctatatataa atatgcttta gcaaatgtaa atttgaggtc tgctaaatct
     4621 actaattcaa gtatcataac agtaatacct cagggagcca aaatggaagt attggatgaa
     4681 gaagatgact ggattaaggt gatgtacaat tctcaagaag gatatgtgta taaggatttg
     4741 gtatcagtaa gcgaatatgc ttggagtaac ttaaacttaa gagaagataa atctacaact
     4801 tccaatataa ttacagtaat tcctgaaaaa tctagggttg aagtccttca agtagatgga
     4861 gattggagta aggttgtata tgatgataaa ataggatatg tttttaatta ttttttatca
     4921 attgatggga ataaaccaaa tgaattagat tataagtatt tttatactga catgattaaa
     4981 tttgttaacg aaaatgatat taaaagtact agcgattatc taattgtaac agaccttaga
     5041 aataaatata cttatatttt taagaaagat aatggaggat ggggacaact ttacaagtgg
     5101 caatgtacta taggcaagcc tgagactcca actataacag gtatatttta tataagtgga
     5161 agaaaacctt cttttggaac ggatgagtat tcaattaaat atgctactag aattaaaggt
     5221 ggatattact atcattctgt gctatatgat tcaacaggaa gttatataat agatggcaga
     5281 cttggtgaag ctcttagtca tggatgtata agattaagta cggaaaatgc aaagtggata
     5341 tatgataata taccagatac aacaacagtt ataattcatt aagaaaaatt ttgagttttt
     5401 tattgggata atgattctta aattaatagg attatatatt aacttctcat aaagagtact
     5461 atttaaaaag tgtaataaga gagtgctatt aacaaaacaa agatattttg aggcactctc
     5521 ttataaatat acataattaa gatattttca taaacaattc tataatctta tctttatcaa
     5581 agaaaacagg attagcacca gcacaagcat ctttcataga gttttctgca agcaattcaa
     5641 aattaggatt atcaacacct acatctttta aagattttgg gattccaacc tcttcagaaa
     5701 gagcttttat cttatctatt acaaagtcaa cacactcttt atctgattta ttatttacat
     5761 ccattccaat aacttcagct attggtcgga atttggcagg ggctgattta gcattttcct
     5821 cctcaactat tggaagtagc atggcattac atactccatg aggtaaatca tataaacctc
     5881 ctaattgatg agccatagca tgtacatttc caagacctgc attactaaag gcaattccat
     5941 ttaaaaaaca agcataacac atttgttctc tagcttctat gtcattacca tttttaacag
     6001 ctcttggaag gtatctaaat atctgcttta tagcatataa ggcagttgaa tctgtaacat
     6061 cataagcacc attagctact acagcttcta tagcatgagt tagtgcatcc ataccagttg
     6121 ctgctgttaa attagatggt ttgctaatca ttaattctgg gtcatttact gtcattgtgg
     6181 ctagtgaatt ggtatcaacc attatcatct ttacatgtct gtcttcatca gttataacat
     6241 agtttattgt aacttcagca gatgtaccag cagtagtagt tatagctatg ataggaagac
     6301 attttttaga agttttgttg ataccttcat agtctctaat atctcctcca ttagtggcta
     6361 atatagagat agctttacca cagtcttgtg gagaaccacc tcctatagtt ataacgaagt
     6421 cgcaattttc tgattttaat attttaagtc ctttattcac attagttaca gttggatttt
     6481 gtttaacttc atcataaaca acaaagtcta tatctatctg agataaaata tctgttactt
     6541 tttttacagt accatttgaa actagaaatt tatcactaac aataaatgct tttttagttc
     6601 ctaatgattt aattgaatct ttagcttcat taagacatcc tttcccaagt aaatttattg
     6661 gtggtacata ataaatgctc ataactaaaa tctcctttta ttttcattga tttttatgta
     6721 aaaatatata tctaacaatt ttcactaatt tactcataat atatcgtatc ttagattgag
     6781 atagggttgc tggttcttat ataagaactt gattcgtaat tacgattatg attagaattt
     6841 aacatagtat ttttatcatg tcaataaaaa tataaaaaaa tattataaaa aaaacaaagt
     6901 tactgtagtt aaatcagcaa ctttgttttt atagtataaa tcaaataaat acattagttt
     6961 aaaacaaaat ttttaattat tatgttttga tatcttcaat atacagaata ttaatctaat
     7021 ttattacaat gtcttcatta cgttcttcca tcattgattg aatatttttc tgagcattta
     7081 agagtaattt ttttatcagt tctatttttt cgtcattagc tctaaataaa ggcagtgtta
     7141 cactaacagc agctcttata catccatttt ttcttattgg tacggcaaga cattttaggt
     7201 gttccattga ttcctcacac tctgaagcta tttgtgttct ttgaacttca agaagctggt
     7261 cgtataaaac atcaaaatct gtaattgatt tttctgtaaa accttttaga ccatctggat
     7321 ataagcttat tagtttttcc ttgtcaaagt cacataaaag agcttttcca agacctgtac
     7381 aattagcagg tatttttttt ccaacataag aaataagtct aattggttct ggagaatcta
     7441 cttttccaat ataaagaact tcattattgt caagtatacc aagctgacaa gtttcagaac
     7501 aggaattaac tatattagtc atttcgtcaa ttatatagtt aaaaatagtt cttttttcaa
     7561 aaaatgaaga ccctaatgtg taagaacgta tccctataga atatttggat gtgtttttat
     7621 caatagtaat gtattttcta gcattaagtg tatgaactat aggaaagatg ctactttttg
     7681 gagcattgat aacatctgct atttctgtaa gagtatatcc attttcggat tctgctaatg
     7741 cttctaaaat atctaatatc ctagctgttg ggcgatgatt atctgaagtc ataaatttcc
     7801 ccctcttttt attaatttaa agtattagaa tatgttgatt ttagcacact atacgatatt
     7861 ttacaatgta gaaaataaat atgtaaattt atatataaat aagctcttga tttagataca
     7921 gatagatatt tttttagact gtacattaag gaataactaa tttccaaaat atacctaaag
     7981 aaagcaagcg atatttagtt atataattta agtaaatata tgcaatagtt atttttatat
     8041 gtaaatatca aaatattatg aacttatatt ttatctattt tttacactgt ataaaaactt
     8101 tatagttttg aatactatat aattttaaat acgctgtatt tttgcatata aggaagtcat
     8161 ttgataatat acaaggtatt atcagaaagt ttgaaaaaat tttgacaaaa atttattttt
     8221 tttattgact cataaatagg aaaatgctat cattaattca aagattcgta attaaaaact
     8281 tagttcttaa atacgaaccg aaacggccgt tagaattaaa gctaaaaact taataagagt
     8341 aattaaatat catgttttag gaggattaac tttatgataa tggattttat taaaaaaatt
     8401 cctgcaggta tgatgatagt gccaatgttt atagcagctt tcattaatac cttttgccca
     8461 gatattgtac aaataggttc gtttacgaca gcagtatttt caagtgttgg gtctgcaact
     8521 ataattgggg ttcaactggt atgcttggga actcagcttc aatttagaga aatgccaaaa
     8581 gttttaaaga gaggtggtat acttcttggt tctaaatttg ctataggtgc tttgataggt
     8641 atacttatag gaaagctatt tggaatggat ggtgtccttg gtctgacaac attggctgtt
     8701 ataagtgcag ttacaaatag taatggtagt atatatcttt cattgatgac ttcatatgga
     8761 gatgaaacag attgtgcaac tatgagttta cttactttaa atgatggacc attttttaca
     8821 ttaatagctc ttgggacttc aggtcttgca aatgtaccat tgttgtcatt attggctgca
     8881 atagtgccaa tacttgttgg tatgataata ggaaattttg acaaaaaaat gaaagagttt
     8941 ttagagccag ggtgtaattt actcgtacct tttgtagggt ttgcacttgg tagtagcata
     9001 aatcttgcaa gtatactaaa aggaggttta tcaggagtat tacttggatt aatatctgta
     9061 tttgtaggag gtatatttat agtattctgt gataaattta taggaaaacg tccaggatat
     9121 gcaggatggg ctgtagctac aactgctgga aatgcaattg ctgtacctgc tgctgttgca
     9181 ttagttgacc catcatggca accatatgtt gcaacagcta caacacaagt ggcagccgca
     9241 gtagttgtca ctgcaatatt agtacctctt ataactagtt ggtgggctaa gaagtatgga
     9301 tgtcctaagt tcccaaaaca aaatgaggat ggtacaataa cagcttaatt tatattacag
     9361 tgagttgttg gtaaaataat aaattcttta attagatttt aggatattaa taaaattata
     9421 ttatttataa aggagagcaa gaataatgat aaatgcagtg ataattgatg aaaaagataa
     9481 tgttgcagta gctattgaag caatagctaa aggtagtgaa attagtttta aattaaaaga
     9541 caaaacagta aaaacgatta cagcactaga tgatataact atttatcata aattggctat
     9601 aaaagatatg gccaaaggtg ataaagttac taaatatggt gaacatatag gagaagcaaa
     9661 tcaggaaata aaaagtggtc aacatgtaca tattcataat gttagaagtg ttagagagga
     9721 tttggataaa caagttatga ctaatatata aaataatatt tatagagtta taaaagttgt
     9781 attcattgct tttagtgtca aatagttttt aaataggttt ttagctgttt gattagtgag
     9841 tgtaataaaa attataatat ataaaaatta taaaaagtat atagactatt ttaggaggaa
     9901 atcagtatga aattttatgg atataaaaga ccagatggaa gagttggtat aagaaaccac
     9961 atattaatct tgcctacgag tgtgtgtgca tcagatacaa ctagaataat agcatcacaa
    10021 gttcaagggg cagttacctt taataatcag aatggatgtt cacaagtaca ttcagaccaa
    10081 caattaacta tggatgttat ggctggttat gcagcaaatc caaatgtata tggtgtaata
    10141 gttgtatctt tgggatgcga aaattgccaa aatgatttgg tagttgatgc aataaaagag
    10201 agaacaaata agccaataaa aactcttgta atacaagaag aacatggaac tttaaaaact
    10261 atagaaaaag ctgttcgtta tgctagagaa atggcacaag aagcttcttt gcttagaaaa
    10321 gaagaatttc caatatctga acttatacta ggaactgaat gtggtgggtc tgacccaaca
    10381 agtggattag cagcaaatcc attaataggt gaattaagtg ataaacttgt cgatttagga
    10441 gcaacatcaa ttttaagtga aactactgaa tttataggtg cagagcatat actagctagg
    10501 agagcagtaa atgaagaagt aaaagaaaaa atattacata tagtacatag atatgaaaat
    10561 tcattaaaat tggttggaga agaagttaga gaaggtaatc catctcctgg aaatatagct
    10621 ggtggtttaa caagtttaga agaaaaatca cttggttgta tacataaagg tggtcataga
    10681 caaataagtg aagtatatga ttatgccaaa caaattgata agaaaggcct tgttataatg
    10741 gatacccctg gaaatgatgc ttcatctgtt gctggtatgg tagcaggagg agcacaaata
    10801 gtggtattta gtacaggaag aggaacacca tcaggaaatc caatagcacc agtaataaaa
    10861 ataactggaa ataaaataac ttttgcaaat atggaagata atatggattt tgatgctagt
    10921 ccagttatat atggtccaca aacaatggaa gaattaacag atgatttgtt aaatatggtt
    10981 gtagatgtag caaatggaaa acaatcaaaa gcagagtccc ttggatatac tgaaatggca
    11041 atagctagag tatgcaacta tgtataatct ttaagtaaga aaataaatac atagaatttt
    11101 aataaagggt gagattatga agtttgtaag ttttactgaa ggagaaaatg aatgtaaaag
    11161 aactggagtt ttttctaaag atgaattatt tattatagat gttaactctt taaatctcag
    11221 tagaaatttt aaggatttaa atgaattaat tcaaaatgta tctagtgaag atattattaa
    11281 gttgaaaact attataaatg aaagtacatt ctataattat gatgttttta aaagagagag
    11341 atgtacggta catgttccta tagaaaaacc aatacatgat atcttatgtg tgggagtgaa
    11401 ctataaagac catcttgaag aaactcaaac tcactttgat gatagttttg aagaaccaca
    11461 aaaaacggtt tattttacaa aacgtgtgac aaaggcaata ggtccagaag atgagataga
    11521 tggtcatttt gagataaata atcaactaga ctatgaagtt gaacttggag tagtaatagg
    11581 taaaacaggt gttaatatta gaaaagaaga ggtagaagat tatatctttg gttacactgt
    11641 tataaatgat atttctgcta gaaagttgca aaaagaacat gttcaatggt ttagaggaaa
    11701 aggattagat acatttacct ctttaggtcc atgtatttta cataaaagtg cagttccttt
    11761 tcccataaaa cttaaagtat gtagtagggt aaatggtgaa gaaagacaaa gttctaatac
    11821 aggattattc atatcagacg tttcagacat agtttcagaa ctttcaaaag gtatgacttt
    11881 agaggctgga gacattatag ctactggaac accttctgga gtagggatgg gattttcacc
    11941 tcctcgatat atgagtagtg gagatgtagt tgaatgtgag attgagagta ttggaatttt
    12001 aaaaaattac attaagtaac tgttttaata taattaatat taaagctaaa tctgatgtat
    12061 taatgaacat attaaaataa attttaggag tttaaattat gaaagcagaa tttttgacac
    12121 cagttgttac aatatttgat gaagaaggaa atttagataa agaaggtaat aaaaaagtgt
    12181 atgaccatct tatagatgga ggtgtagatg gactagtcat aatgggaagt actggagagt
    12241 tctttaatat gtctatggat atgcaaaaag aacttataga tttagtaact agtcatgtaa
    12301 ataagagagt aaaagtgttt ataggtacaa gtcgtatgtg tataaatgaa tctatagaac
    12361 tttcaaacta tgcacataat agtggagcag atggtgttat gataataagt ccttattatt
    12421 tctctcttga tgatgatagt attgagttat tttatagtga aatagctaag aatacagagg
    12481 ctgaaatata tttgtacaat tatccagata gaactggtta tgatttaagt ccagaactta
    12541 cattaagact tgcaagaaaa cataaaaaca tagttggata taaggataca gtaactttga
    12601 tgggacatac cagagattta ataaatacta tgaaaataga gttcccagaa tttaaggttt
    12661 atagtggtta tgatgaaaac tttatacata atctaatgtc tgggggagca ggttgtatag
    12721 ggggattatc aaatttaatt ccagaagttt gctccaaatg ggctgaagct tacaataata
    12781 gagatatgga gaaggttata gaaattcaaa aatatattaa taaagcaatg gatttttact
    12841 taataaccaa tccatttata ccagcaatga aaaaagctat gaatatcaga gggttacaaa
    12901 taagtgatta tatgactgct ccatttgtaa aaccaaatga aaaacaagta tgtgaaatta
    12961 aaaaattgat gaatgaatta aatatatgtt aaatcaacct tgcaaagagg tcaacaataa
    13021 attacaatta tcttaataaa aattaaatta aaataatact agggtactat attagtttaa
    13081 tagggaaagt gatgaaaatt cactacagcc cccgctactg tatacggata cgaaatcaaa
    13141 atccactgaa atttataaaa attttgggaa gggtgatgga ggaaaagccg tgagtcagga
    13201 gacctgccca gtattatata agttcaattt agggtggaga ttgtaattta taataaaatg
    13261 aagtatcaat tcgtttttgt aaagttgata tatgaacttc tccttattaa attaggagaa
    13321 gttttttatt ttattaaaag gttatactta ttaaagatga ctttaggata actttaataa
    13381 gtatacttta aaaagcatat attattaaag ttttttagcc actcataaaa aataagatat
    13441 tggagtgaaa gagatgaaat ttaaatcaaa tgttttaaag cagttttttt taattgctat
    13501 ggtaattttt atggtaggag gtcttatagg gtgtagtaaa agtgacaaag agaataaaca
    13561 agctagtact ggtaagaaat tagaattaaa atatgctagt ggatttagtg ttgaagattt
    13621 agaagatgga attaaaaaag taactgatgg agataatcga gaactgattt taatcccaaa
    13681 gaagattaaa attcctgaaa aatataaaaa tgctaatata gttagaacgc ctgtggacaa
    13741 tgtattaata gcatctacaa cacaggcttg ttctctgaga acaatagatg aactagatag
    13801 tataaaagcc gtaacaacag aagagcagta ctggactatt aaagaaatta aagatttaat
    13861 gaaagatgga aaaatacatt acgttggttc aaatttagca ccagattatg aaaaaatagt
    13921 agacttaaat cctgacttaa ctatagtgag tagtggttta tcagaggctg atacaaaatt
    13981 tattgacaaa ttaaaagaat tagggcttaa ttatgttgta gacaatgagt ataaagagca
    14041 aaatccattt ggaagaatgg agtggacaag tttaatagct gcattttatg ataaagaaga
    14101 tatggctact agtgaactaa ataaaactgt acaaaaggta gaagaagtaa gtaaaaaaat
    14161 aaaaaacaaa gctaaaccta aagttgtatg ggcatctgta tatgaaggaa gtgcttatat
    14221 agctcctaaa gattcatatg tggataatat gataaaaatg gctggtggaa taaatgcatg
    14281 tgcttcaata gattcaaatg aagggcgagt aagtattgaa caattgcatg aagttgcaaa
    14341 agatgcagat atatttgtat actcatcaag ttcagattat gcaccaaatt tagattctat
    14401 aaaatctagt gcacctgtat tggctgattt ggatgttgta aaaaacggaa acctatgggt
    14461 gtttgctcca gattattatc aatcagtaga taagacggac gaattaatag tagatttagt
    14521 tgagatgttc cacccaggta ctacaggtga aaaaatcaaa cattatataa attatgataa
    14581 atagtacaga taggacacaa aaagataggt tttatagatt ttagttaata tagctttgct
    14641 aagaggagta tacaaatgga ttttatcaat aaaatgagaa taaggaatac aacaatattt
    14701 atagtattaa ttataagtat gatacttact tttttagtgt gtgtagcatt tggctctgta
    14761 aaaattgaat ttaaagaagt aatagatgtt gtattaagag gtatggataa tacagaacat
    14821 tataaaataa tatacaatat aagaatccct agagtacttg caaccatggt aggtggagca
    14881 tgcctagcag tatcaggtat tttattacag atatttttta aaaacccaat agttgaaccg
    14941 tatatattag gagtatcttc aggttctact ttatcagtag ctctcatgat tttgggagga
    15001 tacacattgg gatttgagag tgtaaattca atgagtatat ttgtagcagc ttttatagga
    15061 gctttaattg taatgtctat agtcatttta tttgcaaata aggtaaagaa tataacaact
    15121 cttttaataa taggaattat gaccggatat gtatgtagtg gtataacaaa tgtgttacaa
    15181 tcatttgcaa atagtgataa attaaaagaa tttactatgt ggtctatggg aagtttttct
    15241 ggatttacat gggaaaaggt agaaatactt ataatagttg gtatattagg tcttttgatg
    15301 actgtattca taataaaacc tttaaatgct tttttactag gagaagagta tgcaaaaagt
    15361 attggcataa atataagatt ttttagagtt ttgatagtat ttatatctag tatattagca
    15421 gcaatagtat cagcatttgc aggacctata gggtttattg gacttgcagt gccacaaatt
    15481 tcaaaaatga tatttaaaac atcagataat agagttttga taccagtagt aatattttta
    15541 ggcagtatag ttacagctct ttgtgattta atatcaagag taattttatc accagtagaa
    15601 ttaccaataa gtacgataac atctttatta ggagctccaa ttgtagtaat gttattggtg
    15661 aaaaggaagg atagggctta gacatgttga aaactaataa tttaagtgta ggatacaata
    15721 acaaagttgt tataagtaat ataaatgtag aagtaaaaaa tggagaaata ctatgtcttt
    15781 tgggaagtaa tggagctgga aaaactaccc tattaaggtc cttatctaaa cttatatcac
    15841 caataaaagg tgaaatatat ttgaatggtg taaacataaa ttgtatatca agaaaagcat
    15901 tatcaaaaaa aatggcttta gtacttacaa atagattatt aggtgattta atgactgtac
    15961 aagatatagc caatatagga aggtatccat atacaggatt ttttgggagt ctatctaaga
    16021 aagatttaat aatggtagat gaagcattgg agtctgtaga tgccttacat ttaaagaaaa
    16081 gatattttga tgaactaagt gatggagaaa aacaaaaggt gttggttgca agggctcttg
    16141 ttcaagaacc agaaataatt atattagatg agcctacaac tcacttggat ataaaacata
    16201 gattggaact cataaacata ctgaaaaaat taagtaaaga aaagtcaata tcagtaatac
    16261 tttcattgca tgaaatagac atagcattaa aaagttgtga taaagttgct cttataaaaa
    16321 ataataaagt catagcttat ggtcagcctg aagatgtagt agatgaggat attataaatt
    16381 cgctttatga attggatgat aaaaacttta atagtctttt aggttcagta gaaattagta
    16441 ataaatctaa aaatgaagtt tttataattg gtggtggggg taaagcaaca ccaatttata
    16501 gagcttttac taaaaaaggt ataggtctgt attctggaat aatacatgaa aatgatattg
    16561 attatgaaat tggtagaact atggggataa agatgtttac agaaaatcca tttgagccta
    16621 taagtgatga gagtttcgat ttggctatta gaaatttaaa tgattccaag attataatag
    16681 atacaggatt tagtgtagga gagacaaata agaggaatat agatattata aaagaggctt
    16741 taaaattgga taaaaaagtt tattctttta gaaatagaga tgagagtaag aagtattatg
    16801 acagtttgga tagtaagata gaacatatag ataaagtttc tcaaataatc aatagtgcag
    16861 atataaataa tttattataa tttatgaaat aaaatgtact tatgtgctat agaaaaaaga
    16921 gtatagatta taattttttt gaaattacaa tctatactct tttgttattt tgtttatgta
    16981 tttatatatt tataaaactt tagcatttta tagataacca atagcttcct ctctagttaa
    17041 aaaaaagtga atccctgtag ttgattcttt ccatctattt tcattaaaat cttcagctac
    17101 aatcgtttct cctactctat atataaaatt ttcatcagca tatgcacgag cacttttaaa
    17161 agattcttta ccatctatac tagtaattga cagtactttt gccttatcac atctacaagc
    17221 atttgatgta gcagacactc tttttgcgtc gctgggtatt aataattgta ccattctaaa
    17281 attaaaacat tttttatagc ctataaatgc tcctgtttca ggacaataca atttaaaaaa
    17341 acgggtactt tcatctgata ttactccatt taaagtagca tgttctaaat tggaattttc
    17401 taaattagct cctctaatat ctgagttaga taagtcacaa aatctaaaac ttgcaccact
    17461 taagtctgca ttttttaata tagaattttt taatgaacaa tccgaaagat aagaattatt
    17521 aaaaatagag ttttctaaat ctgctttttc taaatttaaa ttgataaggt cagaccacga
    17581 aaagtcaata ttacttaagc agtatcctct taagtctata ttttctaatc ttaattcttt
    17641 taaatctgcc ttttctccag cattattgtt tttaagccat aaataatgtt tctcaagtgt
    17701 tttttctaat ttttgtttag aaatagtttt cattaaaatc accttcataa atttattttt
    17761 atatatgtag tagcaaaata gtcatatatt taattatata acaataaata aaaaacttct
    17821 aaataatata taaaatatca tcttgaaagt acttttttca atatatcaga atatattttt
    17881 aagctattta gagataattt aaatttttaa acaggacata ataagcttgt attgttttat
    17941 atttgagttg ataaaaattt ctttaaataa aaataatgtc aattataaag taataaaagt
    18001 ttagatataa aaaaatttgt gtatatacta tatgtagtat ataatagata aagcactgac
    18061 tatatgtagt gcttttgttt ttgaaaaata cttattgcat ttctataatt atagattaat
    18121 tttgggattt caactgataa gtaccaaaag aaataataag caaattaagt gaaattatgg
    18181 cacaagatta tgttaaaagg acggtaaata atgaattgga tagagcttaa caatcaagtg
    18241 ataattaaaa atgaacaagg caagtaccaa ttggaaaagg ataaggaagc cttaagtagt
    18301 tacatagaag aatttataca gccaaagttg agaaaattta ataacctaga agaaagattg
    18361 aagtatttaa tagatgaagg ttattattca aaagaagtaa taaatcagta tagcatagat
    18421 gttattaaaa atatatatga tatgattgat aaacataagt ttgaatttca atcatatatg
    18481 agtgcaaata agttttatca aaattatgca ttaaagagca atgatggaaa ggaaatatta
    18541 gaaacatata atgataaagt gttaattgta gctttgacac taggaaatgg caataaagat
    18601 ttagctttaa acttggcaga taaaatagta aaacaagaat ttcaaccagc tacacctact
    18661 tttttaaatg ctggaagaaa aagggctgga gaaatggtat catgtttttt actatctgta
    18721 gaagatagta cagaaggtat atcgtatgct atatcttcat caaatcactt atcaaagatt
    18781 ggtggaggag ttgcactaaa tttatctaaa cttagagcat ctggcgaatc tatcaaagat
    18841 atagaaggtg cagctggagg tgttgttgga gtagctaaaa tgttagaaca atcatttagt
    18901 tactttaatc aaatgggagc tagacaaggt tctggtgcgg tgtaccttac tgtattccat
    18961 cctgattttg aattgttgat ggatactaaa aagataaatg cagatgaaaa aataagactt
    19021 gctacattat cattaggagc tataatacca gataaattta tggagttggc agaaaaaaat
    19081 gaagtagcat atgcatttta tcctcatact gtgtataaga aatatggagt ttctcttgat
    19141 gagatagaaa tggatgagtg gtatgataaa ttggttaatg atagtgatat aagaaaaaaa
    19201 gaaataaatc ctaggcagat gttgacaaaa atagcacaga tgcaacaaga aagtggatat
    19261 ccatatgtag tgtacataga tacagctaat agagaacata cattaaaaga tgttggaatt
    19321 attaaaatgt ctaacttatg ttgtgagata tttcaatatc aaacaccttc agaaatagag
    19381 gggtatggag gaaaaaatga atggggacaa gatataagtt gtaacctagg ttctttaaac
    19441 atagctaatg taatggataa taaaactata gaaagtacag ttgaaacagc aataagagca
    19501 ctgtcatttg tagcagatag cacagatata aaaccagtgc caacggtaag caatagtaac
    19561 agcaagtctc attctatagg attaggagct atgaatttac atggatactt agtaagagaa
    19621 aatattttat atacttcaga tgatgctata gatttttcta atgtattttt tgcaatggtt
    19681 agatactatt caattaaagc ttctatgaaa atagctatag aaagaaatca aacttttgaa
    19741 ggatttgata aatcagaata tgttaaggga agaaatagca aggttttatc aaaatactat
    19801 gaacaatctt atctacctaa gtcagaaaag gtaagagcat tatttgaagg gatttatata
    19861 ccaacaaaag aagactggac aaaattattg gatgaagtaa aagaaaaagg gatatataat
    19921 gcatatttaa tggcagtagc accaactcaa agcattagtt atgttcaaaa tgctacatca
    19981 agtataatgc caattactga gccagtagaa gtaagaacat atggagactc tactacaata
    20041 tatccaatgc catttttaac aaatgataat atgttgtatt atcaatcagc atacaggatg
    20101 gatatgagaa aggtcataga tttagtggca acagttcaaa accatgttga ccaaggtata
    20161 tcaacaacac tgtttgttac agatgaaaag acaactagag atatagctag acattacata
    20221 tatgcctata aaaaaggttt gaaaagttta tattacacaa gaacaaagat gacaagagat
    20281 actcatgagt gtctagtgtg ttcagtatag ggagagaaat atatgacatt taatttacat
    20341 aaaatacata atgcagttaa ctggaataga gaagaagatg gatttacaca agctttttgg
    20401 gaacaaaatg taaaacaatt ttggcttcct gaagaaatat ctgtttctaa agacataaag
    20461 gtatggaatg aactaagtaa taaagaaaag gaattatata aaaaagtatt gggtggttta
    20521 acattactgg atacaaaaca ggggaataat ggaataccat ctatgatgag tttaacagaa
    20581 aacctacaaa gaaaagctgt cttgtctttt atggggacta tggaagaaat acatgcaaaa
    20641 agttattctt ctatatttat gactctactt tctaatttag aaatagatga attatttgaa
    20701 tggatagaaa cagaaccaac attacaaaga aaggctgatt tagttttagc tcaatacgaa
    20761 aatactacaa atcaagaggg attataccta tcaatggtta caagtgtatt tttagagagt
    20821 ttcttgtttt attcaggatt cttttatcca ttgtatctat ctggtcaagg aaagatggta
    20881 gctagtggag aaataatatc gcttattctt agagatgagt ctttacatgg taagtatata
    20941 ggattgctag cacaagaaat atacgattca tttgataaaa tggataagga gatgttagaa
    21001 gagaagatgt attctatact ttatagcctt atggagaatg agatagagta tacaaatgtt
    21061 atatacagag aaagtgggct tgaaaaagag gttgtaaact ttttaaaata caatgcgaat
    21121 agagctttag aaaatctagg gtttgagaag ctatatactg tagatgctat aaatccaatt
    21181 gtattaaatg gtcttagcac tgaaaccaaa acacatgatt tcttttcaac taagggtaat
    21241 ggataccaaa aaggagtgta tgaggaatta gaggatgaag attttataat ataatttata
    21301 attatgacac actgttgtca cttttagcgt gataatatca atgtataaaa tatatatgga
    21361 ggtattttta tgaaatatga atggagaaaa agagataaag agttatattt acctaaaaag
    21421 aatcctgtaa tagttgaaat accagaacag aaatttatca tgttaaaagg gagtggagac
    21481 ccaaattcta aagaatttac tgaagcaata ggagtacttt attctttggc atatgcaata
    21541 aaaaccatgc ctaaaaaagg aattgtacca gaagggtatt ttgactatac ggtttttcct
    21601 ttagaaggta tatgggataa gggagaaaaa agtaaaggct tagatgtact tattaaagaa
    21661 gatttaattt acactataat gatacgtcag ccagattttg ttacacaaga cctgttggat
    21721 aaagctactg atatagtaaa gaagaaaaaa cctcataatc ttcttgaaaa agttagattt
    21781 gggtctatta atgaagggct atgtgttcaa atgcttcata taggttcata tgataatgaa
    21841 ccagaaagct ttgacattat gaacgaattt tgcaaaaaaa ataaacttat aagaaaatct
    21901 tacacacatc gtgaaattta tataagtgat gctagaaaag tatcgcctga atcattgaag
    21961 acggttttac gttttgaagt agaaagggaa gtataaatat tttgaataat ttataagagt
    22021 tataaaaagt gaagtctgtt gagacttcat tttttgatgc aattttaaaa ttaaatttga
    22081 tgtttcataa tattttaaaa actttctact tttattagtg tgaataactg ttgctattaa
    22141 ataataatac taa
//
LOCUS       DAEQAF010000060        21471 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.062, whole genome shotgun sequence.
ACCESSION   DAEQAF010000060 DAEQAF010000000
VERSION     DAEQAF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 21471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21471
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.062"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(380..757)
                     /locus_tag="KRN00_002429"
     CDS             complement(380..757)
                     /locus_tag="KRN00_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1828290.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            complement(944..1915)
                     /locus_tag="KRN00_002430"
     CDS             complement(944..1915)
                     /locus_tag="KRN00_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1828291.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            complement(1949..2146)
                     /locus_tag="KRN00_002431"
     CDS             complement(1949..2146)
                     /locus_tag="KRN00_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBH1828292.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            complement(2214..3425)
                     /locus_tag="KRN00_002432"
     CDS             complement(2214..3425)
                     /locus_tag="KRN00_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBH1828293.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSKCGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            3706..4308
                     /locus_tag="KRN00_002433"
     CDS             3706..4308
                     /locus_tag="KRN00_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1828294.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDSSIEVDNC"
     gene            complement(4564..5535)
                     /locus_tag="KRN00_002434"
     CDS             complement(4564..5535)
                     /locus_tag="KRN00_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBH1828295.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(5561..7042)
                     /locus_tag="KRN00_002435"
     CDS             complement(5561..7042)
                     /locus_tag="KRN00_002435"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBH1828296.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLAYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKIKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENNENVYELNINIKNIDSNKFGLELFSSQD
                     EGLKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            complement(7455..8075)
                     /locus_tag="KRN00_002436"
                     /pseudo
     CDS             complement(7455..8075)
                     /locus_tag="KRN00_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005342994.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(8639..9403)
                     /locus_tag="KRN00_002437"
     CDS             complement(8639..9403)
                     /locus_tag="KRN00_002437"
                     /inference="COORDINATES: protein motif:HMM:NF012703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginase family protein"
                     /protein_id="HBH1828297.1"
                     /translation="MPENENQPIVKVEITPPNRKEKLVTDGIYGKNEVIAGIKNATEK
                     IEKENPDKIITIGGNCLVSQAPFDYLHGKYNDLGIIWIDAHPDVSTVNDDYPNAHAMV
                     LGSLMGYGDNALSSLMKNKKFKADEILYVGLQEIHDYQKKFLDETCVNYKIQTDEFLS
                     DKEILSFIERFENIVVHFDIDVLDENLFHSTYFANPDLVGDGSGGGKMTLDKLGNILH
                     CITENSNVVGFTIAEYLPFDEYKLHKLFSKIRMFTE"
     gene            complement(9911..10897)
                     /locus_tag="KRN00_002438"
     CDS             complement(9911..10897)
                     /locus_tag="KRN00_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1828298.1"
                     /translation="MKKITINDIANLAGVSKSTVSRYLNNKDISDSTKEKIKTIIDEY
                     GYEPNAFAQSLRAKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKI
                     RSEIDSISKLASLKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDY
                     GAGYKMGQYIANKGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQ
                     ETSIQRSGEMLESENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSI
                     ISPKLTTIKFENKNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            complement(11282..13036)
                     /locus_tag="KRN00_002439"
     CDS             complement(11282..13036)
                     /locus_tag="KRN00_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBH1828299.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVAKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTEGLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKNYILGNG
                     QPIIEVKNNGINNISIGE"
     gene            complement(13254..14144)
                     /locus_tag="KRN00_002440"
     CDS             complement(13254..14144)
                     /locus_tag="KRN00_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1828300.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGHPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEAISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            14293..15153
                     /locus_tag="KRN00_002441"
     CDS             14293..15153
                     /locus_tag="KRN00_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1828301.1"
                     /translation="MLLKKDRITFSEILILIVGCILMAISLNLFFNPHAIAAGGITGL
                     GVVLNSLFGVELWIVNLLLNVPLFIFAYKILSKKDCFKTVLGIIFLTIALKLTANMAT
                     LDITNDMYLAIISGSILMGVGQGLIFRINGSTGGTDLMALLLNKYFPTFSIPVLMGIV
                     DCVVVVLSGIVNRQVEIALYSTVALYILVKVSDLLIEGFNYSKSFTIISDLSKDISKK
                     IMEDLDRGATILKGEGAYTGENKNVLLVVVEKKEVVELKKLVKNVDPNAFIIITDIHE
                     ALGNGFKKIE"
     gene            15609..16175
                     /locus_tag="KRN00_002442"
     CDS             15609..16175
                     /locus_tag="KRN00_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1828302.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
     gene            16215..16796
                     /locus_tag="KRN00_002443"
     CDS             16215..16796
                     /locus_tag="KRN00_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1828303.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(16853..17770)
                     /locus_tag="KRN00_002444"
     CDS             complement(16853..17770)
                     /locus_tag="KRN00_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1828304.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            17900..19531
                     /locus_tag="KRN00_002445"
     CDS             17900..19531
                     /locus_tag="KRN00_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1828305.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            19534..20481
                     /locus_tag="KRN00_002446"
     CDS             19534..20481
                     /locus_tag="KRN00_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBH1828306.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(20766..21029)
                     /locus_tag="KRN00_002447"
     CDS             complement(20766..21029)
                     /locus_tag="KRN00_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBH1828307.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(21128..21373)
                     /locus_tag="KRN00_002448"
     CDS             complement(21128..21373)
                     /locus_tag="KRN00_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828308.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
BASE COUNT         7133 a         3345 c         2751 g         8242 t
ORIGIN      
        1 gataagttac caataataaa gtttaaaaat ataaaaatca tttcttactt ttagtttacc
       61 tataataaca aaagacaggt ttatattgta ataattaaaa atagtaaaat atattttgat
      121 atggttaaat agaaataata ctttagatta atgaatattg acaagttata aaattatttt
      181 aaattttaaa aatcatttct tatttaaata agtggtatca tttaacttga tactccctat
      241 tccaattatt ttaggcattt tactaattag agaacctatt taatattact ttatgaatag
      301 tgagtagctg attaaataat accatttatg gttttcagcc atagattaat taaattctta
      361 gagttctatc ctgatataat tactcttctt ctaaattttt aaaatgactt tcaaataaat
      421 ccaacatatc tttatcaaca acttcatcat catgtagtgc tgaaattaaa ctctgtaaag
      481 aattgtcgtg tatattgctt aaaaaatctt ttgtctcaac acttaaatac tccttatgtc
      541 caacaactat tgtataatga gtgtatctat ctattttttc tgcacttaaa aaatgttttt
      601 taacaagtct tgataaaagt gtcaatgtag ttgtttgttt ccaaccatat tttcgttcca
      661 tagcttcaat agtttctttt gatgttactg tatcattttt ttcccaaata aacttcataa
      721 cttttaattc tgcttgtggt atttttgaaa ttgtcataac cttacgcccc tctcaaactt
      781 ttattaaatt aatactatcg caatatagtt tttaagtcaa agattttgtc gataataata
      841 ttttccaatt tttaccatag ggttattttt tatataattc tatgataaat tacataaaaa
      901 atatttattt tacatcataa aattagaaat gtaaatagta tgattattta gtcttatctt
      961 taataaacaa tccagtaaat ttatacatcc aaagtgcatt cataaacaac aataaacttg
     1021 ttgaaaaaaa tactgttcta atacctaaat gtgctgatat ttgtccccct aaaaatgctc
     1081 ctgatgaaca gcctatatac tgggcagatg cattatatcc aaatattttt cccacatatt
     1141 cttctggtgc aattttttta agtaagctgt taacagaagg attaagccct gcaactgaca
     1201 accctaataa aaatctcaac aacatcagtt gccatgcagt ttttacaaaa gcttgtggta
     1261 taaatataat cccagcccat aaaagtgaaa ttaacaatac tttttgagga cctattttat
     1321 ccgacatttt tccaagtttt tgagctgcta ataaatttgc taatcctgat gcagaaaatg
     1381 tcaatccagc tattaaagct acatttgatg caaaatttgt aagttgtgat atatatatgg
     1441 ttacaattgg ttctatagag tataaagcta gttgagtaat gaatgtggtt acaaaaatag
     1501 atgcaattaa aaatttattt ggcaatatat ttaattgttc tttaggtata gaaattgatt
     1561 cttttatttc tttaggttta aaattatcta ctacaaataa aatagagatg ataaatgata
     1621 caaacaacaa tcctcctgtt ataataaatg tacttttaag acctaagatt gattctatat
     1681 atcctcctac tgttggacca attaatgagc cagtagttga tgcagttgca agagtaccca
     1741 aagcccatcc tgaatgattt ttatctgtct gtgttgcaat aagagtagta catgcagtag
     1801 cataacccgt aaaaactcct tgaagtattc ttaatcctaa taactgatag acattttgaa
     1861 caaacgccat ggtaaatata actattccca tcccaatact tgcacgtaaa agcattgatt
     1921 ttcttccata tttatcagca gctttccctc aaattggcga aaagaatgct gctactacaa
     1981 aggtacatcc aaaaattata cctgaatact gttgtattaa actaacatca gttaccccca
     2041 actgtttaat atataatgga agtataggtg ctatttggct catccctata gaactaaaaa
     2101 acatacctat ccaacataca aataaatttc ttttccacaa ttccatatag aattacaccc
     2161 cctgcatttt aaattttttc aataatacta agtttattaa tttatgctat tgtttactca
     2221 atatatccat cttttctttt ataatattgt ttaggaaatt cataacttga aaataatagc
     2281 ggtgataaag aataggagta acttccagca ttactaattg aaatcaaatc tcctatgttt
     2341 gcttttttca atttaacatt atttgcaatt acatctaatg atgtacagag attcccaaca
     2401 acatttacat actcttcttc ttttaaatta tttaatactg aaagagaaaa ggcatgattt
     2461 gatgtatata atggctcttg accttctaat tctactccac aagtaatatt ttcaattaaa
     2521 ttagaaataa taggtctcat aaatccatta agtccatttt ttacaataag atattttttc
     2581 cctcttgata ctttaatatc tacaatttta acataataat tacctgattt acaaactatg
     2641 aaacgtcctg attcaataag aagtcttgat tttagtgtgt ttgaattagt aaaagcaatc
     2701 ttttgagtta attttgaaag ctctttaaga ttaagtggat tttctctaag attatcataa
     2761 gctactccaa gtccactacc aaaatttata aattcaatat taatatactt acttttattt
     2821 aaatttaaag ctataaaaaa acatttttca taataatgtc ctaacttttc aaaatccaat
     2881 acctgagatt taatatgtat atgaatccca actacagata cataatcaca catacttaac
     2941 atcttaaaaa cactgctcat atcttctata tctataccaa atttgcttga tttagcacta
     3001 tcatcatcca tagtaaaatc aggatttatt cttattccta ttttaacttt ctgattatgc
     3061 tttttagata tcttatttat aagttctatt tctgtaatac tatctgcaat aattatgcat
     3121 ttatctaaaa cagtttctat atcaatctct gttttgcctg gtgatgaata ataaatatca
     3181 tctttagaaa ctccacattt tgatgaaatc ataacttcat tagttgaaga agcatctgct
     3241 ccaaaacctt gctctgcaat gctttttaca attttgttat atggatttgt ttttatagaa
     3301 tataaaaaat caaaacctaa aatattattt ttcaattcct tacatttttc aattatatta
     3361 gtctcatcat atatataaca tggtgcattt tcttctataa atttatagtc ttcatttgag
     3421 tacatatttt ttacctccaa gattttaaat ataatcataa attaagcaat tataatccta
     3481 taagataatt ttacaataaa ttaccatagt taactacaca catatatgta aaaacatacc
     3541 taaaatattt ttaattatag atacattcca acttttattg ataaaacaat ttgtttcaat
     3601 tttattacaa atatacaaag tgtattgttg ttaacgtatt ctcatagtat cctaaaacta
     3661 tattaagcac taaaaactat tttaaaatac tgtggaggta tcaatatgga agtatgcatt
     3721 cttatgggaa gtcctaagaa aaaaggtaat actgctgcta ttttaaaacc ttttattgag
     3781 gaattagaaa attataattc aaatattgaa gtaatatggt tatatgattg taaaatagag
     3841 ccatgtattg cttgtaaaaa atgtcaggat aacttatttg attttggatg ttattgtaaa
     3901 gatgatgttc agaaaatttt caagaaaatt cttatgtgtg atttaattgt ttttgctact
     3961 ccaatttatt cttggtactg cacttctcca atgaaagcac tacttgacag attggtgtat
     4021 ggaatgaata aatactatgg taatgagaaa ggccccgctc tatgggcagg aaaaccagta
     4081 gcacttatta caacatgtgg atatagacct gaaaagggtg ctgatatttg ggaaaatggt
     4141 atgaagcgct actgtaagca ttcacagtta aaatatatag gaatgcttgt tgaacgtgat
     4201 ttaggtaaac ctaattttat gaataaagaa aaagaagaac attctcgtca atttgcaaaa
     4261 caaatttatt atattttaga tagttcaatt gaagtagata actgctaaag acataatact
     4321 ccaagtaaag tattgataat ataaataaat cttacataat ttgcttattt aaaataagat
     4381 atatattctt ctaaaaagta acaataatta aaatattttt tatcatttca acaatgataa
     4441 agaggcttat ctctattttg agacagcctc tttattgctt tttatatgtt aattattttc
     4501 atagtaaaca tccttaaaaa ctctttacat gttacttcct tcaaaaccta ttactcattc
     4561 ctactataaa ttttttataa attcagttat ttcttccttt gttgcatatg aacttatcgc
     4621 acctttaata gttgtactac gagctgcata ataattagaa aattctaaat actcatttaa
     4681 cgtttcttgt ttcatttctt ttatatcatt caatgttatt tgtttataca ataaggtgta
     4741 taaaaatgaa cctatataag aatctcctgc tccggttgta tctattgcat ttactttaac
     4801 ccctttacac atacctttta cttttttagt gtatgcatct actccatctt ttccttttgt
     4861 atataatact agttcaacat tccccacaaa gagtttatgt aatgattttt ctatatcatt
     4921 ttctcctgtt ataaattcta attcttcatc agatatctta acaatatgag caaaaggtaa
     4981 aaattctgat attgcctttt tacaagattg ctcactatcc cataaaggta atcttatatt
     5041 agggtcaaag cttattatac tattactttc aagtgcgtat tctattgctt ttttatgtgc
     5101 taatttcatt ggactatcta ttaaatctac tgaacaaaaa tgtaggatat gacaattatt
     5161 aaaccactct tttttaactt catcagcttc taaaagcata tctgcacttg gatttctata
     5221 aaatgagaaa tcacgattac catcttcttt taatgataca aaagcaagtc ctgtatttgc
     5281 tttacttgtt ctcaatacat aatcagtatt tacatttact tcatttaata catctattat
     5341 ataatcacca aatgcatctt ttcctaactt agatataaaa cttgattttc ctccaagctt
     5401 tgctacaaca gcactaacat ttgctggagc tcctcctgct actcttctaa attctgatac
     5461 attttttaat ttaccaccat tttgattagg tataaagtct attaaagctt ctcctatact
     5521 aattactttt ttcatctttt ctacccctta taatgtgttt ttataattca ataccttgct
     5581 ttaatttaaa tttagtatac tcatactcta ctattttatc actataaacc cttatttgat
     5641 tagaattttc tttagcaaat attctactag taaatactac ttctccttca tttataaaaa
     5701 tttctaaaat acttctatcc gctagtactt tgatattagt attttcatca atatttatat
     5761 attcttttct atttgttcca tattcaacac cgaaaacttt tttaaagttg cttctgtcta
     5821 aagttacaat gtttcctaat ttgttaaatt ctaattttaa accttcatct tgtgatgaaa
     5881 ataattccag cccaaattta ttgctgtcaa tattttttat attaatatta agctcatata
     5941 cattttcatt attttctata atattgatat tattctttat agtattttgc ccacttgttt
     6001 catcatatct taatttaatt aattcatcta caggcatttg caatagctta ttatttttta
     6061 tatttaattt tcttggaaca gttagacaat gtgcccattt gtttttatct gtagggtata
     6121 aaacttctcc cattccagcc catgcaaata gtattatttg tgagtccttt ataaatgttt
     6181 gtggagcata gaaatcaaat cctttttcca gttctttcat tgtatctatt tcaaatgtta
     6241 aattatctaa atccatatta ccaatagcat atactacatt atatatattt tgataatcaa
     6301 atcctttagg ttctactcct tgtggtgaaa atattaatat atctttttca tctatattaa
     6361 tataatctgg acattcccac atgtaaccaa aatcttcatc tatgtttttt acatttaatt
     6421 ctcctttaaa attccaatct atagagtttt tagattcata tactattata actccttttt
     6481 tatcacttgt ttgtgctcca agtaacataa agtatttatc ctttatttta aatacttttg
     6541 ggtctcttac atgtcctgta tatccttttg gtatttcact tactattgga ttattttcat
     6601 atttagttat tttaccatcc ttgttcatta tagctaagtt ttgatatgca tatctatctt
     6661 ctgcactata ttttatattc cctgtataat acatatgcaa ttttccatct acctctatcg
     6721 cattacctga atatgctcca tgagattcat aactttcgat tggtattaat gctacatctt
     6781 ctctattcca gtttacaaaa tcatcagaac ttacataagc ccaatgcttc attccatgag
     6841 ttgcatcata tggataccat tgataaaata catgatactt accattataa tatgctaatc
     6901 catttgggtc attaagtagt ccatgttgtg gatgtatatg aaatagtggt ttatatttat
     6961 catttaaaga tatatttctt aatttattta attcttcttt tgtcgattct aatatggttc
     7021 tatatttagg ctctttgtac atatttttat tccttttctt ttataatttt atatttgctt
     7081 tattattgct atctaaaaca attcttagtc ttattacaca atgtgctaca ccttttatat
     7141 tttatttatt tcctatgtac tctaataatt actttgatac tttgtaacaa tcagttattt
     7201 ttgcactcat tttgctattc tatcggttta attaaaccgg tttcgaaacc ggtttaatta
     7261 aagattaaca taaatttatt tcagatgcaa tatttctttc aaaaaagttt tcctaatttt
     7321 tagaattata gttttttagt aaaaaacagc atagattttt tagtattttt ttataactat
     7381 cacgaaccgt caatatatcc ctgtttataa gggtctagcg tttttttcat gttgcaggta
     7441 tactgtggaa ctggtcataa tcccttatat ttctgctcgc aatagttgta caaatcgttg
     7501 taaatcatgc tatcatgctt tcgcaattct ctgtttgctc ctgcctctga cgcataggcg
     7561 tataagtcca gcgttatcgt tatgcttgca tgccccattg tatattgtaa atttttcggg
     7621 ttcatgttct tctgtacaag ctgtgtacag aacgtatgtc ttaggctgtg gggtgttatc
     7681 ttcagcaacg gtgttttctc atggttcttg ttgtacttct ttacaacacc gttcagcacc
     7741 gatttataat tgctttcttg catagggttt ccgttgggac tgatgaatag gaaattgcgg
     7801 tagccatcta tatctttgag cgttggcttc tgcttccttt tcagcactcg gcgaaaggca
     7861 ttctctgttt cttcgctcat aggcacgttg cggaaactgc tctttgtctt tggctatgct
     7921 atgtagaaac cgtccttatc tttaagtagc tgatgattga tacggattac atggttcttg
     7981 aaatccaaat cattctttgt cagtccgcaa agctccgaga tacgcaagcc tgttttcctt
     8041 gcctgtaaga cgtgttccaa gtgccgacag cccatacccc tcaattccgt aaaacgccca
     8101 tagaaacgtc tttagaagct gtaacgataa tctctccata gatatattgt tcttcatagc
     8161 caaacagtcc gtaatcttca tgaataattt aagttttgcc tgctgatgtg cagttccttt
     8221 ggcagtcttg tttgggaata accgcaggcg ttccgctttt ctttcaatgc ttcaataaat
     8281 tcaatgtcat tcatgtttta ttcctccaat caaaaaaggc atacgcccat aggagcatac
     8341 accttgtatc atgtattttc ttgctgtcga tatactgttt tccaccaatt gacaaggtgc
     8401 gaagtacagt aagtgcttat aaccttataa atcgttgcat atcgggattt ttgtaattgt
     8461 tctgtctctt gtttcttgta atagtccccc ccctgttaga taacggggct tataaggctc
     8521 gcttcgcttg ccaagccgcc gaagtgaacc acccctagcc agtggcgata tgtcttacga
     8581 ccgccacagt gggcggacca ctccgtcggt ttgaaatatt ccacgttaat caaataagct
     8641 attcggtaaa catacgaatt ttagaaaata acttatgtag tttgtattca tcaaaaggca
     8701 gatattctgc tattgtaaat cctacaacat ttgaattttc tgtaatgcaa tgaagaatat
     8761 ttcctaattt atccaatgtc atttttcccc cgcctgaacc atcaccgacc aaatcagggt
     8821 ttgcaaaata ggtggaatgg aaaagatttt catcaagtac atcaatatca aaatgaacga
     8881 ctatattttc aaatctttct ataaacgaca aaatctcttt atcagataaa aattcatctg
     8941 tttgtatctt gtaattgaca catgtttcat ctaaaaattt tttttgataa tcatgtattt
     9001 cttgaagtcc aacatataat atttcgtctg ccttaaattt cttgtttttc ataagacttg
     9061 acaacgcatt gtccccatat cccattaaag aaccaagtac catagcatgt gcgtttggat
     9121 agtcgtcatt gactgttgaa acatcagggt gtgcatctat ccaaataatt cctaaatcat
     9181 tgtattttcc atgcaaatag tcaaatggag cttgtgaaac caaacaattt ccaccaatcg
     9241 tgattatttt atctgggttt tctttttcaa tcttttctgt ggcatttttt attcctgcta
     9301 taacttcatt ttttccataa ataccgtctg tcactaattt ttcttttctg tttggtggtg
     9361 tgatttccac tttaacaatg ggttgattct cattttctgg caaaatatga gacattaaat
     9421 ttgcgccaaa aaaatattgt tctaaaccac cactcacata atcaggatat aataatcgta
     9481 ttgttttcat ggtatcctcc taaaattata attttcttca attatagcat gatatatttt
     9541 tatcgtcatt tcttttctgc ttttgaaaag ttacttacca gtccatgatt tgtaaaggat
     9601 gctattcaac attgcttacg caataagcca ttgacaaacc atagactaat aagttttaag
     9661 gtaatcaagc agaaatgaaa tagtatgctg ttccactgca tagaaaaaga cactctgttc
     9721 aagtgccgtt ttcttatatc tttgtatttc tctttataag tcgttacata aggctctttc
     9781 atttgttcta attttccgtg ttttcttttg gttgttttgt tgatagatac tgtatttatg
     9841 tggatatttt cgattttcta tctgtttttc acgtaaaaaa tacacattac taatatatgt
     9901 aatgtgtatc ttaattttta tttattgtac tttcaccttc tattaattca aatttaatct
     9961 cctttaatag tggttctttt ctttcttgta ttaagtttac tatcgtattt gctgctactt
    10021 tacctgcatt tttattttca aactttattg ttgtaagttt agggcttata atagacaata
    10081 catcatatcc cccaaatccg gctacagata tatcttgtgg tatactttta cctctcttat
    10141 tgatttcttt cattgttgct attgctatat tatcagttgc acatattatt atatctggat
    10201 tttcactttc tagcatttct ccacttcttt gtatagacgt ttcttggtca aagtcagtat
    10261 aaaatacttt tgcatcatac cctttatctt ttaacccatt aagtactcca ttttttctat
    10321 ttaaaccaac tgatatatca ctttcatcaa cacctaaata tacaatgttt ttgtaacctt
    10381 tattagcaat atattgaccc attttatatc ctgctccata atcatcattc actatgctat
    10441 tgataccatc aactttttgt ccaactacaa ctatcggtat atctaacttt tcaatttcat
    10501 tcttatgttc tttagttatt tcggtaccaa ttagtattat tccatcaact tttagactag
    10561 ctaactttga tatactatct atttctgacc ttatttttct attagtatta ataattagtg
    10621 atgtatattt taattctttg agttcttcat ctattgccat cataatttta gattttacaa
    10681 aagaatctaa acacggtgtt ataataccaa taaagtatgt ttttttagct ctcaaacttt
    10741 gagcaaatgc attcggctca tatccatatt catctattat tgtctttatt ttctctttag
    10801 tagaatcact gatatcttta ttatttagat atcttgatac agtactttta gatactcctg
    10861 ccaagttagc aatatcattt attgttattt ttttcatagg ttatcacctt ctacatttga
    10921 tatattttat tacattatat tatatattta aaataaaata tagttatttg tccagtcaat
    10981 actttttata tactacttgt actatccata tccacatcca aagaattgag tctttaacat
    11041 taaattaatt gtaattttca ttttttgttg ttatatttaa tttcaatttt atctactatg
    11101 aattgataaa tactttaatt tatttataat ataaaaataa ggctatgatt tttacaacca
    11161 tagccttatc gataaatact taattatcac ttaaaaaata attttttatt taaagaatat
    11221 atataaatat tttaaaattc tataattttt aaaactatat aaactttatt ttcatatgtt
    11281 tttattctcc aattgatata ttatttatgc cattattttt aacttcaata attggttgtc
    11341 catttcctaa aatataattt ttagaccaac cttctggtaa tttatttatc ccatttccaa
    11401 ttaacttcaa gtgtaaattt gatggttctt ttttcagatt taatttaaat attccatcaa
    11461 aggtaccttt attatcgctt ccaaataaac ttatattgcc atttatattt gtagctgtta
    11521 catttacaat tccattgttt gctctaaatt ttatttcaga tgatatagtt tcagctgtta
    11581 cacctgaaat cccactatta gtatttatat tgaaaggatt tgttacattg ttatcaacaa
    11641 tgttagcaat tccgtcattg acatcaacag tagctcctcc tttaatatta taaagttcta
    11701 ctgaaccact ttcaacatct actttaaaat tagaatacat tttatcggga actccaattt
    11761 ttatcacatt taccatccta tctttatttg catttatcat attgtcgcca ttcatatctt
    11821 gcaaatcact atctttctta tctatttttt tcttagcact tacaactagc tttccatttt
    11881 ttatattatt agaagaattt tctttatata cagaaaaagt acaatttttt tcattagtta
    11941 cacttacgta atcaaactca aatttattgg tattcgtttt ttcaacaacc acacctaaat
    12001 tatctgactc tataagtatt tcagaaactt catttccttc aactgaagtt aagtgtttta
    12061 aaatatttgg agtcatatcc atattattat atttaatcat atctaaacac tgtttatata
    12121 tattggcatc aatacctcca acttttgtta tacttttagc tccttttaaa atacctttat
    12181 tacttccatc agcaactaaa acgattggtt tttctttggc taaaggagat aatgttagtg
    12241 catctactaa ttgatatcca tttgttatat aaaaatctgt agctccatta taaaactttt
    12301 ccattacctt tttattggtc tcaaatctat catttcctcc gattctagtt gctttagttt
    12361 catttactaa atcctcattt atcgcagatt tgccacctat agcgtaaaca tttaaacctt
    12421 cagtcttaaa tggaactgat ttcccatctg taagtattat agctccttta ttttttgcaa
    12481 ctacaggtgc tatactcata gcatcagcct ctcctacaaa tccatttgta agcattacct
    12541 cttttacact acttacttca tttatttttt tagctacatt ataactagtt tcaattctat
    12601 tgttaccatt tattctttcc acttgaatac cttttctttt tatatctttt tctactgaat
    12661 tttcaatagt attataacca ccaattatat atactttttt tacaacattt aaactcttat
    12721 tatctagtct atttaaagta gcttttggta tttcactttt tttagtcaaa agtattggtg
    12781 cgttaatagc tccagctaat ccacttgatg aaagcccatc agataaattt ttatctccat
    12841 taactaatat tacagtatca taagtttgtc tatccgctat aagtcctgct gtttcatatc
    12901 tatcaattcc tattattgaa tcttctttaa tctgtgcatt tgcagttaaa ttattaaaaa
    12961 gaaacatagt caaaactaaa attaatatac ttagtttttt actgaatttt ttgaattttt
    13021 tattcataat atacactatt cctcctgtaa attaaggtct ttaatttgct tataaattat
    13081 ccccttattt acaaataata acataatatt atagtaacgt atatattacc ttaaaattat
    13141 cagtaacttt atatcaatca tcttagctta tttatataaa tttttttata ttacttttca
    13201 aataacagtc atactaaaac aatttcatca tataatttga aaattattac tatttacaca
    13261 gcttttatca tcattttacc accatcaaat atatattcaa ccatattatt ctcatataaa
    13321 taagttatat aagaacgtat tgtacttcca accaacacat attgattagc atcaagcttg
    13381 acattgtaca aatcacacat tttttcaata acttcatcaa tcataactgg ctcataacaa
    13441 acctttttaa tattatctat tatttcttcc atcttcttct tattaatatt aattaaactt
    13501 tttatatctg tagttttgac agagtgactt ggaacaaaga aatcagcctc taacattctc
    13561 aatttttcta gtgtcttaaa ctgtgaatct atatccagta ggaagaaaaa atgatattta
    13621 gtaattatat tctctggtgt aagactatct gcaacaaaca aaacattatc tggagttcta
    13681 acaccaatca tttcaaaata atgacctgga agagaaatcg cttcaagttc tgtatctaca
    13741 attttgccat ttgaagggat aatataatca acttcacttt cctttgctaa taaaaattta
    13801 ttcttcagtg ctttacttgg atggccacca tataaaaatg ctgattctaa tattggattt
    13861 tctgtaaaat atccttcaat tttagtcgta gcaatcttgc attttgtttg attcttcaaa
    13921 tatgcatttc ctcctatatg gtctgcattt gaatgagtgt ttattattaa tttaggattt
    13981 aaattatgtt cttctaataa tcttaaaact tgtctagctg tatccttatt atttccactg
    14041 tcaattaaaa ttgcatcctt accatctacg tatacaccta ctattgtagg gagtggaata
    14101 taatatgtat ttccttttat atgttctaga gttaatttag ccattttata acctcccttt
    14161 aaatttactt ttaattatag cattaatttt ctgaaaattc caatcaaatt gtttttataa
    14221 tatattttta tttcttttat taaaaattgg aaaaactata taatatatat tataatctat
    14281 atataaggag tgatgttatt gaaaaaagat agaataactt tttcagaaat tttaatatta
    14341 attgtaggct gtatattaat ggccatttct cttaacttat tttttaatcc acatgcaatc
    14401 gctgctggtg gtataacagg acttggagtt gttttaaatt cattattcgg tgtagaactt
    14461 tggattgtca atttactttt aaatgttcca ttattcatat ttgcttacaa aatactttca
    14521 aaaaaagatt gttttaaaac ggttttagga ataatttttc ttaccatagc acttaagctt
    14581 actgcaaata tggctacatt agatataaca aatgatatgt atcttgcaat tatatctggt
    14641 tctattttaa tgggagttgg tcaaggactt atttttagaa taaatggctc tacaggtgga
    14701 actgatttaa tggcactcct actaaataaa tattttccta catttagtat acctgtttta
    14761 atgggtattg tagactgcgt tgtagttgtt ttatcaggta tagtaaatag acaggttgaa
    14821 attgcacttt attcaactgt ggctttatac attttagtaa aagttagtga cttgcttatt
    14881 gaaggattta attattccaa atcattcact attatatctg acctttcaaa agatataagt
    14941 aaaaaaataa tggaagattt agatagaggt gcaactattc taaaaggaga aggtgcatat
    15001 actggagaaa ataaaaatgt acttttagta gtagttgaaa agaaagaagt tgtcgaattg
    15061 aaaaaattag taaaaaatgt cgaccctaat gcttttatta taattacaga tatacatgaa
    15121 gctttaggta atggatttaa aaaaatagaa taactaacaa ataaatagca agtataatta
    15181 acatatacaa attcaacttt ttatatgtta tattatactt gctatttata tattatactt
    15241 gctatttata tattataatt gttgttttta agataaaaat taaatgtatc aattattgtt
    15301 ttatacaagt atttccaaat ccgttctcat ttagatagta tgcttagaaa ttttagaatt
    15361 attgagtcta actttattac ttactttact ttataacaat caaatacaaa tttaaatatt
    15421 ataaaactac aaaataattt aaagcatata atgtcaatat gtttaaatta taaaatattc
    15481 atgtagttat ataataaata atttataaat atagccaact tagcctaaat acgtatataa
    15541 tatagctaat atggttctta tacttgatac catcaataaa actaaaaata taaaaaggag
    15601 aacttaaaat gagtgttagt ttacaaaaag gacaaagagt tagcttagta aaagataata
    15661 atcctgtaaa aaatctagta gtaggcttag gatgggatat gaataaattg ggtaaaaaaa
    15721 attatgacct agatgcattt gcaatagcat tgactaacca agataaaatg aatgttagag
    15781 gtgacttggt ttattttgga aatcttaaac acccttctaa agctattata cacactggag
    15841 ataacttaac tggaaaaggt gaaggtgatg atgaacaaat aattgttaat ttagaagaca
    15901 tacctgaata tgtacataaa atagtttttg gagtttctat atacaaagct aaaaaaagag
    15961 accaggattt tggtcaaatg aacaactctt ttataagatt aattgattca aattccaagc
    16021 aagaattatt taaatataat cttcaagaag acttttctgg taaagtaaca gttttggcag
    16081 gagaaattta tcgtagaaat gaagaatgga aatttaatgc tttaggaatt ggtcaaaatg
    16141 aagagcttcg tgaattaatt aatacatata agtaataatt acaataaaaa atttataatg
    16201 aggagttggt ttaaatgggt ataactttag caaaaggaca aaaagtaagt ttaacaaaaa
    16261 gtaaccctgg tctaaaaaaa gtaatagtag gactaggatg ggatattaat aaatatgatg
    16321 gtggctttga tttcgattta gatgcctctg catttttaac tggaactgat ggaaaagtaa
    16381 cgaatgatgg agactttata ttctataata atttaaaaca cgcttctgga gctgttgaat
    16441 atatgggtga taatagaaca ggtgttggtg atggtgatga tgaacaaata aatgtagact
    16501 tatctaaaat acctcaaaat attgctaaaa tatcatttag tgttactata aacgaagcaa
    16561 ttacaagaag acaaaatttc ggacaagttg aaaattcata tataagaata tataatgaag
    16621 aaactaatga ggaacttatt aaatatgaat tgggtgaaga ttttagcata gaaacagcaa
    16681 tagttgtggc agaactatat agacataatg gagagtggaa atttaatgct ttaggttctg
    16741 gatttgagga tggacttgca ggattgtgta aaaattttgg cgttaatata ggctaatata
    16801 tctaaataaa aataagagta tatttatata ctcttatttt tatttagata tattataaac
    16861 tgtttacact tctactcttc tttctcgctt gttttttccc atattctact gaaatatcaa
    16921 aaaatgctga aatattttct gtaaaaaact tgcttctatg atatgcaata tcaaatgtcc
    16981 tatgtaaatt aataccttca atatcacaag cccacaaaag atgctttttt aaataatcct
    17041 caataagtaa ttcggatata actgcaatgc caaaattatc tacaactgct cttaatatag
    17101 cttcagagtt ataacatgac catctaatat tcattgggat ttttaattct tttaattgct
    17161 tttctaattg tgctcttgta ccacttccta attcacgcat aattaatggt tgatttgaaa
    17221 gttctgaaac ttttatagag tctcttttgt agaactcatg cttgtgtgaa catataagta
    17281 caagattatc attaataatg ctttttgtaa caatatctgg gtgcttaatt tttccttcta
    17341 caatcgcaat atctaattca ctattaagta atttttttgc aatcagtctt gtatcttcta
    17401 caaatacttc aggttctata agaggattta ccttgtataa ttctaacatt attggactta
    17461 ttacacatgt accaacagtt actgttgccc caactcttat acggatattt tttgcacaat
    17521 gcttcataca atcattcatt tcttcattta cagctaaaag atgcctccca tatccaagaa
    17581 gttttttccc tgcctcagtt aaatataatt tttttgaaat tctatcaaat agcttaacac
    17641 catactcttt ttctatttct gaaatagctt ggctaactga tgactgggta atatacatat
    17701 ttcttgctac ttcactcatt ttaccacatt cagcaacctt aacaaagatt tcaagactac
    17761 gaattgtcat attatcacaa ccttagcaaa cattagtaaa tgcttatgat tttattaata
    17821 ttttagtatt ttacaaatat attgtcaaga agtataattt tattatagag ttataaagta
    17881 gattggagtg tgatatattg tgaaagtatt aattataggt ggagttgctg ctggaacaaa
    17941 aactgctgca aaaataaaac gtgaaatggg tgataattgc tctgttacaa tactaaataa
    18001 aggtgatgat atttcttatg ctggttgtgg tcttccatat tacgttggta agataattga
    18061 agataaatca tctttaatcg taaatacacc tgaaagtttt tctaaactaa caggagcaga
    18121 agttcgttgt ggagttgaag ttacatctat tgatagaaat gcaaaacaag taactttgaa
    18181 aacgctttca acaggagaaa aagaaaatct aagctatgac aaacttgtaa ttgctacagg
    18241 ggcagaccca ataaaaccac caatacctgg aatagattta cctggagtat tctttatgcg
    18301 tactccaaat gatgctataa aactaagaga ttctattgaa aacggtatta agagagctgt
    18361 tgttattggt ggaggtttca ttggtcttga aattgctgaa aatctttctg caatgggtat
    18421 acgtgtaagt gttgttgata tggctgaaca tgttatgcct ggatttgata ctgattttgc
    18481 tgaatacgtt gaaaatcata tggctgataa aggcataatg atttttacag gtgaccaggt
    18541 tgtaggtatt gaaggtgaaa ataaagttga aaaacttcgt actaaaaata gagctattaa
    18601 aacagattta gtggttatgt cagttggaat ccgtcctaac acaggttttc taaaagacac
    18661 aggtttagaa tttgccccta ataatacaat tattgcagat gaatatatgc ttacaaatga
    18721 caaagatata tacgtagttg gagactgtgc ttttgtaaaa aattctttaa caaataaacc
    18781 tacatggtca cctatggggt catctgcaaa tcatgagggt agaatttgcg cacaaaatat
    18841 atctggaaaa tctaaaactt acaatggtgt tcttggaaca acagtagtaa aattacctga
    18901 gctcaatgca ggaaaaacag gtctaagtaa agaaatagct gaaaaagaag gttataatgt
    18961 ttgctctgta accatagcta ctgatgataa agctcattat tatccaggtg catctaattt
    19021 tattataaga atggttgctg aaaaaaatac tagaaaatta ttaggtgttc aagttatggg
    19081 acctggagcg gttgataaaa tagtagatat cgctgctact gcaataactt taggcgctga
    19141 cctttattca ttagaaagta tggaccttgc atatgcacca cctttttcaa cagctattca
    19201 cccttttgta gtggcagtaa atgttttaca aaataaactt aatggagaac ttgatagtgt
    19261 tttacttgac gaaattgagg attttgacag ttggactaaa cttgatgttt caaaagctcc
    19321 ttctattcct agtttacgtt atattcctgt tggtgaaatt aatggagaaa ttgaaggcct
    19381 tgctaaggat gaaaaaattc ttcttatatg tgctaaaggt aaaaatagct atatggcgca
    19441 aaatcgctta agacgctttg gctatacaaa tacgaaagtt cttgaaggtg gaatactatt
    19501 ttatccaaat cttaaggtaa tggaggagta aatatgagta atgttacagc agaacaaaaa
    19561 aaggaagtaa aaggtagagg ttttctacca agcagggatg gagaacattt tgcagcacgt
    19621 ataataactg taaatggtgt aataaatgca tcacaagcaa aaaaaattgc agaagctgct
    19681 gaaaaattcg gaaacggtca gttagcattt actactagac taacagtaga attacctggt
    19741 gtaaaatttg aagatattga agctctaagt gaatttattg ctagcgaaaa tctaataaca
    19801 ggtggaactg gatcaagggt tcgtcctgtt gtggcttgta aaggtactgt ttgtgttcat
    19861 ggtctagctg atacacaggc acttgctgct gaaatacacg aagaatttta caaaaattgg
    19921 tatgatgtaa aactacctca taagttcaaa attggtgttg gtggatgccc taataactgt
    19981 attaaacctg acctaaacga tcttggaatt gttggtcaac gtgtacctga ctatgattca
    20041 gagctttgtg ttggttgtaa aaaatgtgct gttgtagagg tctgtcctgt taaagcagct
    20101 aaattaacag ataaaggtaa acttgaaata gatagtaatc tatgtaataa ctgtggtaag
    20161 tgtatagaaa gttgtaattt tgatagtatt gaagaaaaag aatctggtta taaagtctat
    20221 ataggaggga aatggggaaa atcagttcgt cctggaacac agattgatag attattttca
    20281 aaagaggaac ttatgacttt aattgaaaaa gcaattcttt tatttagaga acagggtaac
    20341 acaggtgaac gttttggaat aactatcgat agaatcggtg ctgataaatt tatagaaatg
    20401 cttttatcag atgaagtttt ggaaagaaaa gaagagatac tagaggctct tttacacctt
    20461 acaggtggag ctgtatgcta acaataaata ttttaattgt acagataacc tatggaaaaa
    20521 attttagtta agaataatta aaattctata tatgatatat gataaatgag gctatctcaa
    20581 aacacagata cgcctctttt tcattgttga aatgataaag tatatttaag tttatacaaa
    20641 aaagagtgtc tcgtgaatta taaaattcat tttgaggcac ccacattatt ttataataat
    20701 tgcttattaa ttttatttta actatataaa aagtacaaaa agtaagaata tccaatattc
    20761 taaaattaat tttgaattgt attgattgaa aagtttacta ttccactatt tccatcttga
    20821 tttactacta gataccatgt tccagtatta ggaactctca ttctacatgg atttttcttt
    20881 gcaaatccac catagtaatc ataatttctt tgatttttaa atttcacata atttatatgg
    20941 tctaacaata ttacattggc ttgtttctct aaatttacct ctacaatatc cccttttttt
    21001 aagttcatct tactataact atattccatt gaattactcc tccagtatcg aataatcttt
    21061 gttatttact catctcaaat atgtaaaaat tcatttaaaa tattacaaat actatataat
    21121 tagactatta tccagtttta accttattta ctacaatcca aaggttatta aaaatattat
    21181 tggcaacaac ttctccatcc catacaactc tttcttcttt attttctaat aaagcatagt
    21241 acccagagtc agaactttca tctttataga ctgtaacata aaactcttca tcactatatt
    21301 caggtatatt tttaaagtct tcagatattt tacatgttaa tatataacct tctaattctt
    21361 catctataaa caaagcaatt cctccaatct ctatattttt actaattata ccatattatg
    21421 tcataaactt tttattttat tacaaatttc tattttttct ttactttata a
//
LOCUS       DAEQAF010000061        20947 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.063, whole genome shotgun sequence.
ACCESSION   DAEQAF010000061 DAEQAF010000000
VERSION     DAEQAF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20947
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.063"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(40..729)
                     /locus_tag="KRN00_002449"
     CDS             complement(40..729)
                     /locus_tag="KRN00_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1828309.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            complement(792..1640)
                     /locus_tag="KRN00_002450"
     CDS             complement(792..1640)
                     /locus_tag="KRN00_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1828310.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            complement(1659..2546)
                     /locus_tag="KRN00_002451"
     CDS             complement(1659..2546)
                     /locus_tag="KRN00_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1828311.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGRGATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKGVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            complement(2604..3407)
                     /locus_tag="KRN00_002452"
     CDS             complement(2604..3407)
                     /locus_tag="KRN00_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828312.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            complement(3567..4019)
                     /locus_tag="KRN00_002453"
     CDS             complement(3567..4019)
                     /locus_tag="KRN00_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBH1828313.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DVFVNIVEYRTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEEGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            complement(4149..5651)
                     /locus_tag="KRN00_002454"
     CDS             complement(4149..5651)
                     /locus_tag="KRN00_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH1828314.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YCMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            complement(5684..6550)
                     /locus_tag="KRN00_002455"
     CDS             complement(5684..6550)
                     /locus_tag="KRN00_002455"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBH1828315.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            complement(6635..7306)
                     /locus_tag="KRN00_002456"
     CDS             complement(6635..7306)
                     /locus_tag="KRN00_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBH1828316.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            complement(7579..8070)
                     /locus_tag="KRN00_002457"
     CDS             complement(7579..8070)
                     /locus_tag="KRN00_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1828317.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            complement(8092..9456)
                     /locus_tag="KRN00_002458"
     CDS             complement(8092..9456)
                     /locus_tag="KRN00_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1828318.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLVNPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIKTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            9875..11050
                     /locus_tag="KRN00_002459"
     CDS             9875..11050
                     /locus_tag="KRN00_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1828319.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            complement(11223..12620)
                     /gene="asnS"
                     /locus_tag="KRN00_002460"
     CDS             complement(11223..12620)
                     /gene="asnS"
                     /locus_tag="KRN00_002460"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBH1828320.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     misc_binding    complement(12697..12930)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(13099..13293)
                     /locus_tag="KRN00_002461"
     CDS             complement(13099..13293)
                     /locus_tag="KRN00_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBH1828321.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     gene            complement(13566..15239)
                     /locus_tag="KRN00_002462"
     CDS             complement(13566..15239)
                     /locus_tag="KRN00_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBH1828322.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLDPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            complement(15249..18647)
                     /locus_tag="KRN00_002463"
     CDS             complement(15249..18647)
                     /locus_tag="KRN00_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1828323.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDMGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYSSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLPNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            complement(18815..20011)
                     /locus_tag="KRN00_002464"
     CDS             complement(18815..20011)
                     /locus_tag="KRN00_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBH1828324.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSINYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            complement(20032..20853)
                     /locus_tag="KRN00_002465"
     CDS             complement(20032..20853)
                     /locus_tag="KRN00_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBH1828325.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
BASE COUNT         6743 a         3759 c         2226 g         8219 t
ORIGIN      
        1 tttaattaaa attctaataa tactcttact taatcataat taattatttt taaaatacct
       61 tgataattca gtttctttaa cataaaaacc tttattgtca attttaataa gttcttcttt
      121 ttgcaatacc tttatcattc tggaaacagt ctccctttta cagccaagca tatcagctaa
      181 atatgtaact gtaatattta catttagtaa agtccattct ccacagcaaa ctccaaattc
      241 tctacttaac ctatataatt ttgctgcaag ttttttatct acttttatgg atatagaatt
      301 tttcaactgt ctatataaac gtcttattct tctttccata taagaaataa tatcctttgt
      361 aagttgaaaa tcattttgca taatttctaa aaattcttca atactataat aagctacaat
      421 tgaattttca aatgcttcac agccaacagt agagttttta gaagcgtcaa gtgtaatatc
      481 atttatgact tccccactat ttaatatgaa aattactttt ctctctccat tttcacttat
      541 cttaaaaata gatacctttc cttctaaaag tatataaaca ctgtctaagc tatctttttc
      601 ataaaataaa atttcttttt tttgtaatct ttttagttta actttttctt taagttgatt
      661 cttcgtttta gtacttaaat tattaaaaat tattacttta tcaatattat aatcttttaa
      721 tttagacatg taatatctct ccattcctaa gtttttaaga gagctctata aaacattaca
      781 aatttcttat tttattcatt tttaaacaat tttatagcat ttgtagtttt aattttcctt
      841 tcaatagctt cattagaaag ttcttttact acctgtgtat atactaaatc aataatgaaa
      901 aattgtgcta atttagaaga tattgaaccg gtttccagta ctgtttctcc cgatacataa
      961 gataagtgta catctgaaat atcctttaat tcagaatttt tattttcagt aattgatata
     1021 attttagcat tattggctct tgcaagcttt acagttttta taatctcttc tgtttcacca
     1081 gaatgtgaaa ttgcaattat taaatctcct tcttccatta tggaagacat cattatcatt
     1141 gtatgactac tgtcaaaact tacacaatta agacctattc tcataaattt atagtttgaa
     1201 tcctgtgcta ttataccaga atatccaata cctatgaagt aaactttctt tgcatttatt
     1261 ataagccttg cgcagtcatg tacatcctta ctattgatta tctctactgt gttctctaaa
     1321 gtggttacat ttgaacttaa aagttttttt gctgtatcca aagctggctc atcattttgt
     1381 atatttttat ttataatatt ttttttattg atagttgata tttcttgtgc taaagtaact
     1441 ttaaaatcct gtaatccatt aaaattcatt ttttttacaa acctagttat agttgcttca
     1501 ccaatattgc tctctttagc tatttgtgat attggtttat aaaatacatc atctatattt
     1561 tcttttatat aagctattaa taatttatct gattttgtga ctttaaaagt tggtgattcc
     1621 aattgttcta aaatactcat taaaaaccct tctattcttt atattttgtt taaaaaatta
     1681 tataatgctc caagcattcc tgcatcattt tgtctctttg caaattctat attagtgttt
     1741 ttgtaaactc tctctataag aacccccttt aatgctttgt ctatttttgg ttttaggaac
     1801 ttttcttgtg ccataatccc accacctaaa attaccactt ctggatttat tacataacat
     1861 atatttgcga ttccaactgc taatgatttt atcatattat cgagttcttt taaacaatct
     1921 tcatcattat tctttgctaa atcaaaaatt atttttccat ttaagtcatt ttcattcaaa
     1981 ttttttattt ttgctacttt tttaattaga ctgctagtag atgccaattc ttgaaaagaa
     2041 cttccattta cattcatata tcctacttca ccagcactat tactaaaccc atttatcagt
     2101 ttattattta ttataataca tccaccaatt ccagtaccta ttgttaaaca tatagaagat
     2161 gttgcacctc tacctgctcc aagccacatt tcaccaagtc cagcacaatt aacatcattt
     2221 tcaacttcac attttatatt aaactctttt tctacttctt tttttaattg catgccctta
     2281 tagtttggaa ttaattcttc taatgcaaat agtattttac cttcaactgg gtcaaccata
     2341 cctgcagttg atatacatat accacttatt tcattttcct ctatatattt ttttactata
     2401 tcttttattt tggctaatat tccttctcca cctttttcct ttgcttcagt atcaagactt
     2461 gatttatcaa ttataaatcc atcttctcta ataaaaccat attttattga agtacctcca
     2521 acatctatac aaacgtaatt tttcataaca tatctccata caaattattt ttataaatta
     2581 acaactctat ttaaaatttt atattacaca aatcttttac ttatcttttc caattcacag
     2641 atatatttcc ttgcttctga taagtctata gtatcactta atacactttt ttctttggtt
     2701 atatgatact tataaatatt tttacataag tcctctccta acatattaag accttcttga
     2761 gtgtaatgaa catcatcaat agttaatcct ctgtcatgaa actgcatagc aattttgctt
     2821 cctacacata atatatcaca ttcactacaa gccgactcct gtgctgctgc aattcgtctt
     2881 gttctaataa aatattcatc ttctccaagc caataaccag ttaaacttac aaacatttta
     2941 tcaatcatac attcttcttt aagcctatac gcaatttttt ttagactttc tttatagtac
     3001 aatacatcac taccatattt tgcatcactt tcaccttgaa tccaaataac gtatttattt
     3061 tctatattat aatgtttact taaggtagta cagcctgtat taaatttttc tatagtgtca
     3121 tttagaaacc agttattatc atgattccag ttttttattc ttgaaccatc ttttgcattg
     3181 tgaataaaac aaactttatt tccagtaagc ttattccatt catttgaaaa tgcaggtgct
     3241 atagtaccat caccttctga agtctctagc tcacatctca tatttataat ttcatcagta
     3301 ctcaaatatt caaaacaatt ttcatttgga atgatgctct cttttggatt tcccaatcct
     3361 ctagcattgc tttgtcctat taataagaat acatctatat tttccataag ttaactcctt
     3421 tacaaaattt taagctttta attattttca attttctcat aaaaaactaa ggctgaaaat
     3481 agtaatctaa ctaaaattta cgaagtctca ctaatcgctg aaagttaaat cactattttc
     3541 agccctagtg gttatataaa ttatcattat ctaaccaaaa ccttaaaaat agcttttttg
     3601 atattttctt tttctaaaac ttttattcct gtcatatgag catcttccgg ataacaaact
     3661 aaaaaatcac cttttctaag ttccatgtat ccattatttt taccatcaag aggcaagaaa
     3721 tcgccctctt cttcatatat tttttgttct aaattttcta taaaatttat atctattcgt
     3781 tcacatccat caagcatcaa atgaacatct atatacttct tatgagcttc ccagaatcta
     3841 tcttcttttt cacaagttct atactctaca atattcacaa aaacatcatc accatctatt
     3901 gtataagtac ctttttcata atctattaat gaattatctt tagcatattc aaaacatcta
     3961 agtaaatctt catgcaatgt tgaatatgtc ttactatgat ttatatttcc aaatatcata
     4021 agcactatct ccctatataa ttataaagtc tatttttata cttttatata caaagtatat
     4081 tatacaatct tatagagcaa ctaaattatt tatctaatca ctctataaga caatttatca
     4141 tttaaatatt atttttcata ataaacagta gtctcagctt ttggtaaaga tacttttgct
     4201 ttaactttag cttctattgc actaactatt gtacctacca ctacagaagt cgtgattgtt
     4261 attagagaat atgcccaaga agttacttct ggcatacagt attttaaata aacaactaaa
     4321 attgctgata ctatgaatcc aacatatgct cccattttag ttgctttttt acaaaatgca
     4381 ccaagtacaa atattcctgc taaaacacct agtactagcc ccataaaact attgaaccat
     4441 tcatatgctg actttatttc tccatttgct aatactattg caacagctat agaaagtata
     4501 cctacaccta atgatatata ttgtgctatc ttagtttgtt tttccatact tatatctttt
     4561 gttatgatag tttgtatgtc taaagtccaa cttgtagcaa ctgagttaag ccctgtcgat
     4621 aaagttgatt gagatgctgc atatatcgct gcaagtagta ttcctgttat acctactggt
     4681 aattcataag ctatatatga tgcaaatact tggtcttgtt gaactgtttg agctaaatct
     4741 gggttttgag tatagtatat aaataaacaa gttccaatta gataaaatac tgttgcaagt
     4801 cccattgata aaacaccatt tccatatgtc attttattaa gttgctttat atcagttgtt
     4861 gtagtaaatc tttgaactat gtcttgactc gatacatatg atgaaaaagt attaagacca
     4921 gctccaacaa atattataaa tgcacttgta gatagtatat ttttatcaaa cataacttca
     4981 ttacttgcta agaacttgtg tccagttgta agagtatcca ttactgttcc aaaaccacca
     5041 tttatacttg ctattaaata gaacaatgtc cctgtaacac ctactattaa taccattcct
     5101 tgtataaaat cggtccacaa gacagccttt aatccacctg tatatgagta aattattgct
     5161 attacaccca taactattat cagtacattt acaggtattc ctgtaagacc agccagaact
     5221 attgatggaa gatacattat aatagacata cgtcctattt gatatattat aaacatcaaa
     5281 gctccaagta ctctaagacc tttactttcg tatctcattt ctaagtattc atatgctgta
     5341 tctatttcta acctactata tagaggtaag aaaaatttta ttgtcaaagg tattgctata
     5401 aacataccta attgtgcaaa ccacaaaatc caagtaccac cataagaatt tcctgctaat
     5461 gataaaaatg atattggact taataatgtg gcaaatattg atactgatgt aacccaccac
     5521 ggaatagttc catcaccttt gaagaactct tttcccttca tttccttttt tgaaaataac
     5581 aatcctgcaa ataaaactgc caataagtaa accactagta ttgcaaaatc tatccaagta
     5641 aatcctacca tttgactaat cctcccatac taaaagtatt ttattaaaaa tactttctgt
     5701 atatttcttt tgctcttgat ttcatttcat cagttgcttc tttcataggt tgtctacagt
     5761 atccagcctc aacaccttgt tcttcaagta gtaatttaat tgtttgatat aagccatttc
     5821 ctaatatatc tgttattaaa tcattagtca catgttgtac ttcaagtgct tctgatattt
     5881 tttcattctt agttaattcg aatatttgtc tagctctgac accgtttaca ttgaatgtag
     5941 aaccaattgc cccatctaca cctaaaactg tagctggtaa catcatttca tcaaatcctg
     6001 caaatattaa tttatttggg aatgtttttc tcattctctc taataagtag aaatctgctg
     6061 ctgtaaactt aacacctatt attttttcat tttcaaataa ttctccaaac tggtctaaac
     6121 tcatatcaac accagttaaa aatggtatag agtatattat taatctatta tctacagaat
     6181 ttattattgt attataatag tgttttattt cttcaaaatc aaatttatag taaaaaggtg
     6241 taacagcact tattgcatca tatcctaaat cagttgtaaa tttagcaagt tctacagctt
     6301 cttttaaatt aactgaacca acttgagcta ttaattttat ttcttctttc acttcatctt
     6361 tagctatttc aaatattctt ttcttttcat cagttgaaag catgaagttt tcccctgtac
     6421 ttcctcctac ataaagacca tctactttac aaacatctat attgtgtcta attatttgtc
     6481 ttaacccttt ttcatttata tttccttcct tatcaaatga aactaataat gctgaataaa
     6541 ttcccttcat atctgttgtt ctcatatctt tacctccaat tttaattttc aaatatagtt
     6601 aaatataata attttttaat ttataaatta atttttaatt aatttcaatt gctttaacaa
     6661 atttttctgt tattaattgt ggtcttgtta ttgctgaacc tactactgat gaatgaacac
     6721 ccaactcaaa gacctttttt aaatcttgag gagtatttac ctttccttca gctattacag
     6781 gtatttctaa atctttaact aatctttcca ttaatacaaa atctggacct tctaatgttt
     6841 tagtatatgg agtatatcca gatagtgtag ttgaaacgca atctacaccg tactcttgtg
     6901 ctttgatagc ctcatcataa tttgaaatat ctgccattac tagaacaccg ttttctttta
     6961 tatactttat aagttctttt aagtcttcat tatttggtct aactctattg gtagcatcta
     7021 atgctatcat ttcacaccct gttgttaaaa gttcatcaac ttctttttta gttggcgtta
     7081 tatatatatc tgaatcttca tagtttctct ttataatacc tataacagga agtccagtaa
     7141 ctttttttat ttcaataata tcttcaactc cttgagctct aattccaaca gctccacctt
     7201 ccatagcagc cttagccatt ctccccatta taaaaggact atgaagaggt tcatcttcta
     7261 aagcttggca tgatactatt aatcttccct ttaccttatc tagcattttt taaattacct
     7321 cgtttctgaa atttattttc ttgatttatg tattaataat aacatgaaaa ctttttcttt
     7381 gcaatatttt ttcatatttt tttctcgcat ctatattttt actgatttat tttatatatt
     7441 agcttgtttt ttacatttaa aagaaatttt atttcatttt tttggtgttt attttcattt
     7501 tatataacta ctgttataag tccatttaaa taatttcaat aaaaaaaccc atgtatacta
     7561 tacataggtt tcccaatatt attctaaatc cattataatt tttcttccac agcatggaca
     7621 aaattcagcc tctgtatcta tctcactttc acaataacca caaattataa aatcatcaca
     7681 ttcattttcc aattcaaatt ttttaccaca ttcagcacaa tatttatcat ttacatttcc
     7741 aacataacca cactcacaag ttacattact ttctgccatt tccatttcat taatttccat
     7801 atttttttca taaattaact tatcaagttc tagtaactca tcacagaatt tatcaaaact
     7861 attatcatta atagaatctt ctctaatttt ttgatatgtc agtattccca tttccaagaa
     7921 tatctttgct ttcttttctt gaatatcatc aatctctcta tttaattttg atttttcttt
     7981 atataattca actttaaatt ttccactacc aaactttttc ttaaccttag aaaatttatc
     8041 atctacttta ttattagtat ttccttccac agaaattccc tccaatcata tttaatcagc
     8101 tgaatttagc ttatatccta ttaaagatat cacaaaacta tatacaaatg aaattacaat
     8161 agcttgtaag actttaaatt gcattattaa agttgttcca taattagttg tattaaagaa
     8221 attaatatta ctatctagta taaatgtact aaataaagcc aatattccca tcaaaaatgc
     8281 ataatatata ctaaatacta ttataggtct tatactatct gtattatact taaatcttag
     8341 cttgtatcca tttaataata atattaacat agacaatgct cccattgcat aaaacattaa
     8401 tttagtatct ccaaataaag atgaagaact taaagtaaac attgatactg ttgagtttat
     8461 tatggttact gaaattccat ttgcaaaagc ccacatataa ctagctattt gtgggagtat
     8521 agtaaataaa tttaatccat ttgaataact actcatatct agttcattta agtaactact
     8581 atcagatata gttagtacca atagtattac taatactaaa acataaccta atatgaatgt
     8641 ttttatagaa tttgaaaaaa gagataaata catattttct ttttcataac tttttttata
     8701 agtagttatg tatgtacata taaaccctaa tacgaatcca tttaaaagaa cactaaaaaa
     8761 ttcataacta tattctaatg catatccata ttctaacata ctatgtgaac tagtttttac
     8821 attagtaaaa atagataaaa tagctaaaac taatccataa aaaattccaa ctcctagaga
     8881 atttgctaat acagtttttg aatctctaca tctttttctc ataaaaatta ggtttgatat
     8941 taataatacc aaaataggga ttataagtaa tatcaacaaa cctatattgg catttataaa
     9001 cccagaaccc atcatggtag acatagatac actaatttga cccaagttga gagctaggat
     9061 tatatgtgct ggatttacta aataactaat atcattaaat tgaatagtta taatagcttt
     9121 aaatatcaat gcaataataa acaatataaa tatggttgta aatgttgtta aaaatacacc
     9181 tcttttattt gcatgatatg aaagctcttt tattttagat ttcaagtcta gttttgtttc
     9241 aagtggtctt aatgatgcta tttcataaag ttcatttcca caaaatttac agtaattatc
     9301 cttagtatta ttttctttat tgcaactaga acaaattttt tcttctttac ttttaagagt
     9361 gatatggcta ttttttattt ttctagttgg ttcacctgtc tttttggaat aattattatg
     9421 tgaataattc atattattta ttttcttttc acccattttt tccctccaag ttttactatt
     9481 gtaaattatc aaatataact atatcatata aaacttaatt ataccttaat tggatatatt
     9541 tatctatttt atttgtttat tgctgttgtt ttttaacagt tcttgatatt taaatagttt
     9601 gttaatgcga actttattat ttatatttta ttatgcttaa tttaaattta ttctattctt
     9661 tattttcagt agtaaactat ctgtaaatct taattataat aaagtattaa tcaataaagt
     9721 tactcgacat tatctaataa attttatcta tcacaatttt agattgttac acacaatata
     9781 ttttgatata attaaatcat aaacgaagta ttccaaatat ctaatgatag aaaggaatac
     9841 ttatttttat gctttatttt taatggaggc ttatatgaac ttagaaaaaa taaaaaaatt
     9901 ttttggattt cctctagaca aaaaacacaa agacaatgtt gagaaagaac tctgcaatta
     9961 tctttatcat acgggtaaaa tcatttgcat aataatagta atatctcaaa taattatgat
    10021 gatatcaatc tcagctagag aaggaggccc ttttgtcaca ccaagacgcc aatggtattt
    10081 ttatatgtat gtaacactat tttgtgtatc ttctgtcttt atgtttgtat tttcttacct
    10141 ttggaataaa aaaaaggatt gctgtacgtt ttatataaat ttatggataa tttatgtgac
    10201 ttttttctgc ctatggggtt gtgtaattac tctacttgac cagttaggtg gaaatgacct
    10261 aagtgtattt agttatatta tgttagcagc tgcagctttc tcagtattaa aatttggaga
    10321 atcagtaata gtttttggag gatgcttttt gtttcttaat ttattcttac ctgggattca
    10381 aactatacca ggcaatgagt ttagtaatat tgtcaacaca ttttttataa catcccttgc
    10441 catttttgtt tctacaatgc tatatagaaa tcgtgtattt acttactatg ataaactttt
    10501 aattagtcaa caatatgaag aaatatctca tataaataat ttacttaacg acaaagttat
    10561 gacagatgac cttactaaaa tgaacaaccg tagatacctt gaagatattc tacaaaaaaa
    10621 attaatcagc catgcaaatc aagaacctat aactggaatg atgatagata tagattattt
    10681 taaacaattt aatgataatt atggacatca aaagggagac tattgtctac aaaatattgc
    10741 caaagtaatt ttagatttta caagttctga aaatgaacat gctatacgat atggtggtga
    10801 ggaatttttt atatgtattt ttaactgtaa tgaggcagat gctaaactta aatcagaatg
    10861 tttacgaaaa attatagagt cctgcaattt tgagcgtgat gatgttcctt taaaatgtgt
    10921 aactgttagt attggagttt atacaaagaa aattggaaag acaataacat taaatgagtt
    10981 tataagtaat tgtgataagg ccctatatac tgcaaaagaa caaggacgta attgtgttgc
    11041 attttattaa aaggttacat actattacat aaacctataa gtattatatc gcaaaataaa
    11101 agtaatcaaa ttatatattt atagtacaat aaaaataact tgcatatctc taaaatagat
    11161 aaatatgcaa gtcattttag tgtttatact taaagttata taagttttat tatatataat
    11221 tattaaaatt cagcattttt aggagttctt gggaaaggta taacgtctct tatgttagac
    11281 atacctgtca tatacataat tattctttca aatccaagac caaatccaga gtgagtagca
    11341 gtaccaaact ttctaagttc taaataccac caataatctt cttctcttaa tcccatttca
    11401 ttaattctat ctaacaatac atcttctctt tcttctcttt gagaacctcc tacgatttct
    11461 ccaactccag gaactagtaa atccattgct ctaacagttt taccatcttc attcattctc
    11521 atatagaaag cttttatatc ttttggataa tctgtaacaa acactggaca attatatatt
    11581 tgctccgtta tatatctttc atgctctgtt tgaaggtcac atccccactc aacaggatac
    11641 tcaaattcat gcccagattc aattaataat tccactgctt tagtatacgt tattctaata
    11701 aactcagagt ttactatctt atttaatctt tctaacaatc ctttatctat aaaactatta
    11761 aaaaattcca tttcttcagg agcattttct aatacatagc ttataacata ttttatcata
    11821 tcttctgcaa gttccatgtt atcttcaagg tctgcaaaaa ctatttctgg ctctatcatc
    11881 caaaattctg aagcatgtct tcctgtataa gagttttcag ctctaaatgt aggtccaaaa
    11941 gtataaacgt ttctaaaaga aagtgccatt atctcggcat ttaattgacc actaactgtt
    12001 aaattagcct cttttccaaa gaaatcttga gtatagtcta ttttgccatc ttcagttttt
    12061 ggaatatcat ttaaatccat agttgttatt ctaaacatct ctcctgcacc ttcacagtca
    12121 ctacctgtta tgattggaga atgtgcatat acaaagtttc tttcttggaa gaatttgtgt
    12181 attgcatagg cagctattga tcttactcta aatacagctg aaaaagtatt acttcttggt
    12241 cttaaatgtg ctatcgttct taaatattca agcgtatgtc tcttcttttg tagtggatac
    12301 gaactatctg attccccttc tacaactatg ctttttgcat gtatttcgac tggttgttta
    12361 gccccttctg tagatactaa ctctccctct acaagtatag atgagcttat tgctaatttt
    12421 cctacctctt taaaattttc tactttctca tcaaatacta tctgcatatt tttaaagaag
    12481 cttccatcat ttagctctat aaatccaaaa tttttagata ctctagatgt tcttatccat
    12541 ccagctactt ttacagtctt ccctatgtac tgttcttttt ctctgtacaa ttcttttact
    12601 gttataaatt ccttttgcat tttaaatcct cctagtataa ttgttattaa tttcttttaa
    12661 atataatttc aataaaaaaa gcccttcatc cctatataaa gggacgaaag actattactc
    12721 tcgcggtacc accctagttg tcataatgac ctcttagtta agcaatgctt aaagcctata
    12781 acggtgcctt ccgtctaagt ctacttacta aataagcttt cgattagaaa ctccaagatg
    12841 ttcttcaata taaacctcgt attgagcttt caccatcctc aactcgctag aactacattt
    12901 tatatctact cttctcttca cagtatttat cttttattat ttctgctaat taacaaaatt
    12961 ataccaattt ataaattttt agtcaataaa tttatataat tgatactgat tgttatttaa
    13021 aatataataa ttctacctta cataatgata ataaatactt atcttcatta cttctttatt
    13081 acttcaattt ccaaaatttt ataatttact tccattgtca acccagtctt ttgcttcttc
    13141 gacaccctta attgaaggta ttgaaacttt actatgaggt tttaattttt caacatcagc
    13201 ccatgctgct gtcgactcat ttccaactaa aagtgaactt ttaagtcttt tattatcttt
    13261 accttttaat gctcttgcct ttttactttc caaaactatc acctctatta tttattttgt
    13321 aatagtttta gcaattttac aaataaaatt cataagtcta aattataatt atttttaaat
    13381 taacatcata tcttttcaat acttaattta tacctattta tatacaaaat atttactttg
    13441 tgtattcaaa atataaaact gttttttaat tttcatattt attttttatg ctatttttct
    13501 actctatcta aagtatttga tacaattaaa ctaataatca attataattt tacataggtt
    13561 cttatctata gagtatttgc tatctgttga atcgtatttt ttaaatttaa aatcccatat
    13621 ccctgcgata catttggata tgtatatatc tcaagttttg tagcacccaa tattaaatat
    13681 gtttttaaaa cttgtgtaaa caatgataat ctcggtacat tatcctgttt ttctaagtat
    13741 tccatcaata aggctaaaac acctgtgact atagaactgc tcactcctgt tcctgttcct
    13801 gtattatatg ttccattttt atatgtggat attatatcta cacctgaagc tactatatct
    13861 ggcttaattc ctcttcctct aattggtcct ttcgaagaac caatccacat actatcagtc
    13921 ttattgttaa atgtaccaac tgtaattaca tcatcactag cagcatacat agttatagta
    13981 gctactgaat cagggtctaa aaaccttgtg tctggagcta tcaaattttt atttggcaag
    14041 tatatgtcat attctccatt tattataagt tctgaagtca atcttaaaat ccatactcca
    14101 ggttttatat ctcttaatct tatctccaaa ttttcttttc cagaggtaat atatggataa
    14161 ataaatctca ttgcataagt agtattttct aagttaaatt ttcctctata tatataaaag
    14221 tctggagaat accttatatc atgactaact tcacctgaag gagatattat ctgtgctccc
    14281 actttatctg gaccattcgt atttagtgtt atatcaagag catagtcatc tccatcttgt
    14341 attattacat cttgaacttc tcccacactg ctaaatctgc cagaataatg aatatctgta
    14401 ttcccttgat ttcctgcacc actcactact accacaccag cactactcaa tatattaaaa
    14461 gtatctagta ttgaagtagt tgctacagca cttgacttaa ctccaatagt caaatttatt
    14521 atcagtggtt tattttctgt tcttgctatg ttagtaacat acgttatagc tgctaaaaaa
    14581 tctgaaacac tgtaatttat ccttccagca taataagtat ctgtatatga ttttaattta
    14641 actactatta agtctgattc tgtagtaata cctctgtact gagaatttat ccttccattt
    14701 ccaactaata taccagaaac taaagttcca gtacctatat tatcttgact caaactccca
    14761 tcatttctat ttatggctat atttaactca cttcttgtaa attcacttcc aaaaataaaa
    14821 ccttctggag gtggatttgt atttgcttct tggtcccata aatataaaac tttactagtt
    14881 ccatcatcat ttataaaatc aggatgcaaa taatctatcc cagaatctat aactgctaat
    14941 aaaattcctc tccctgttat atcattatat ggattttcat aaatataatc agtttcagct
    15001 gctgttgtaa tggtttctcc attatttaca ttattagtta tttcaattag actgctcatt
    15061 ggttcagatt cttcccacca agcaacttgt attatattat ttaaaatagt ttcatcaaaa
    15121 tctaaaggta catatattac tgcaagctga ctatttaaaa ccatatacct atttattcca
    15181 ttttcttgta gggcagattc tatatcacct tgataaatta tacaataaga tttttccata
    15241 aatccctcct atcttaaaac atcaaacatt cctctaacat ccaagagccc atatccagaa
    15301 tttgtatttg gatatactgt gtttgaatct tttctagcac cagcttgcat aaaagttttt
    15361 attttttgca catatgcttg gtttggatat ctaccgtcaa caaaagtata ttgaaaatac
    15421 attgcagcag caccagctgc atgtgcactt gctgctgctg taccagttat agttgcatac
    15481 gtgttcccag gataagcagc tattatattg acacctggtg ctactatatc tggttttaac
    15541 ctgtcttcaa tagttggccc tcttgatgaa ctttgccata aactaccatt aatagtattg
    15601 taggctccta tggttattaa atcatcttga atcgcaggat aatttatagt gtaaaaaggg
    15661 tctacctctc taaatctagt tccacttttt aaaagttctc tatttggaag gtataagtta
    15721 tatcttcctg ttataatata aactcctact aatcgaatct tccatacacc tctttttgca
    15781 ttctttaaag taacattagt aaattgctgt ccagaaaaag ttgttgggta tatatatgtt
    15841 atagaatatt cagtcccctc taaatcaaat aagcctgtta ctttattata atttgaaatt
    15901 ccaacacttt tactttcttc accagtggga gatactatta ttacatcagc tttatctggt
    15961 ctatttaacc aaagttctaa tgataattct tcctcgtctt catttaactc taattcaact
    16021 tcaacagaac ctccaacata tggtattatt ccagatgtat gtgtctgtgt attaccctca
    16081 tttcctgctc ctgccgttat acataaccct ctagtaaaga acgctttttc actattactc
    16141 ctattggtta aacctgctag gctactggta cctaaagaca tatttataac taatggtctt
    16201 ccaagttcaa aagctttttt atatgcatac tgagatgcag caaacaacat tgcactatta
    16261 taaaaatcat ctatcttgcc gagttttatt attattagct cagaatcttc tgctatacct
    16321 gcatattcac tatttacatt tccaagccct gcacatatcc cactcaacat agttccttga
    16381 ccaacttcat cctgagatag actagggtca ttttctgcga tagctcgatt tatatcttct
    16441 cgtgtatatt ctgtcccaat ataaaaacca tcaggaggag ttccttcttt tgtttggtcc
    16501 cataaatata ctatttttga agtgccatct ggataaataa aatctgggtg tagatagtct
    16561 attcctgtat ctgcaattga tattagagtc cctcttcctg ttatattaat attaggatta
    16621 tttttaaaga aatttacgcc catttcttct gttgcaacta cacctccaaa agtacctcga
    16681 ttaatttctc caagtaatgt catctttgta gtcgatacag ttcttatgat tgaaggaagt
    16741 tgcaaaactc gttgtatact actatagtct gtattattta tagatagtac acctaatgaa
    16801 tcacttatct taaaaaacct ttgactcata cctaacccag ctagttcttc ttcaaattca
    16861 ggagtatgga ctatatctat tcctgatagt attcctgatt gtctacttgc atttttactt
    16921 atataaattt cattctctaa gtcattatgt atttgcatat tataaccatc tataaactta
    16981 taactatttt cctcatcttt aaatgactta ttaatacttc tatatcccat atcctctgtt
    17041 tctaaatctt gatttatatt agatagagtg tacaaatcta tatctgataa atttaaaaaa
    17101 ccaaatcctg atgaattatt tggataagat tgattactta atctccttgc tccctttaga
    17161 agtaatgccc ttaatttctg tgaatacaaa aataaatcat ttccatttac aattccccat
    17221 tccataaaca atgaacaaac ccctgtaaca tgaggtgtag ccatgctagt tccagttaat
    17281 gctccacttg tacctcctgg taaaaaagat actatatctt cacctggagc taataaatca
    17341 ggtttaaaaa cacctaattg tgtatctcct tcaccagaaa atatagatac tatatctgtt
    17401 cttgaattaa aactacctac tgttataact ctacttgctg ttccaggaac tgttacagta
    17461 agctcttgag taggaatcag aaatctagta tttctattta gaccttcaga agttggcaaa
    17521 tatatattta cattaccagt tactatatct attggttcaa atacaatttt ccataaccca
    17581 ggagttatct gtgtatttga acttaattgt agagtaactc ttcttgtgag agaatacggt
    17641 gctatagggt aaaaataacc agttattcta gtttcaccca aagtattcct tatctcacct
    17701 gaagttagag agattgcttg tgtttgatta tttgatgggt ttaccaaatg tacactaaaa
    17761 tcatcaacaa aatctggcca tatatttatg tttaatatac gctctccttc cccaactata
    17821 aactcaactt cttctgtaat attattttga agcctaatcc ttttatgacc tcctttatct
    17881 gcattatttc cagctgctac aactatattg tttttccaaa ataaacacat atcatctata
    17941 tattgttcaa ataaagatgt tcctctatgt gaaccttcat tacttccata acttatattt
    18001 aatgtaacag gcattcttaa ttctaatgcc ctatctaaaa taaatttaat tgccctcata
    18061 aactctgtac ttctcgaaaa aatatcggtc tgtatatttc caactctaac cactattatt
    18121 ctggcatcac ttgcaatagt tgcacaaata cctgcaacat gtgtcccatg taagctagtt
    18181 gttgaaatag gtatatacat acttccatct attgcattat ttatatcttc attagtatat
    18241 aatgttcctt ctctaaaacc ttctggtgga tttccttgaa tagattggtc ccaataatat
    18301 aatatcttag accttccatc actatctcta aacacaggta gagtataatc tattcccgaa
    18361 tcaattatac caattatagt tccttttcca gttaaaccag ttctattttt aaatcctgtt
    18421 attcctgtac ttgaaaaact ttgcacatcc tgagtctgta atataaaagg cttttctata
    18481 aattcaattt ctggataagt taaaagtata tttacatctt cttcattact tgatgttatt
    18541 attgcatatg atgaattaag tatctctact gatacaccta attcttcttc taacctcaat
    18601 atatctccat tgtattttac aattaattca taatttatta taatcacctc gacttctaaa
    18661 attattatta atgtatatgt tttgtgtgag tctaaaatgt attagactat ataatttttt
    18721 aagtttcagt tatacaattt ataatagata tattaaaaaa aataaataat gatggtacaa
    18781 ttttgaataa atcataccat catttatatt tactttatct tgaaaccatt aaatttttca
    18841 atgctttctc aagacctttt acagtcaatg gaaacatatt aaattcactt tgtatcattc
    18901 tttgagtttg ataccaataa ttaattgaat cccatccatc tctaagttct ggattcatcc
    18961 atacaatttt actgtacttt ctcttaaacc ttttaagcca ctctatacca ggtgtgtaat
    19021 tatatggacc acgatagtta ccaccaatat gaagcaactc agaaggcgac atagaagcat
    19081 ctccaacaat tataacttta tagtttttat ctatattttt taatatccat tcagtattaa
    19141 tagatttact taaccaacat tcaggtgttg taaataatct atcataaata cagttatgga
    19201 aataatatat ctttacatct ttaaaatgat ttgatttact tacagactga aataatgtat
    19261 tacataaagt gctataccct ctcattgaac cacctgaatc cataagcaat aaaagcttca
    19321 ctgtattttt tcttggcttc tcaaaaaata actttaaata tcctgcatta ttacaagtct
    19381 cttcaatagt cttatccaaa tcaagctctg tctttggagc atctattctg gtagaaaatt
    19441 gacgaagtct ctttagtgca acttgaaatt gacgcatatt taaaacttca tcatctctaa
    19501 aatctctgta ttttctttct cctgcaactt caagaacagc tctaccataa gtagaatttc
    19561 cacctatacg tataccagtt tgcccttttc ctgaatgtcc taactctgaa gtgcctcctg
    19621 tgcctatcca ataattacca ccattatgag gagagtcttg ttcttttatt cgttcctcca
    19681 atttagctct taatttatca agatttatat ttggattttg ttctaatctt tcaaactctt
    19741 ctaaatctat atctggtttt ttaagccaat tcataatctc ttctggaatt tcttcttggt
    19801 gttctatacc tttaaaatac tccaaaaaca ctgcatcaaa cttatcaaaa tcactttcac
    19861 tttttattaa aatcatcctg caaagatagt aaaaatttga aaagtttgaa tagcacagtc
    19921 ctttatccaa tgcttcaatt aaagtcatcc attcatttaa agatacattt aatcctcttg
    19981 acctcaataa ataaaaaaat tcaataaaca taattatcca gctcctatta actataagtg
    20041 tctttgcata gattcaatat cctcattatt cttaagtagt attcctgcaa aaggaacttc
    20101 tttttctatt ttttcaatag gcattccact caaagttaat gcttgtatcc agtctattaa
    20161 ctctgatgta ctaggctttt tttgtatgtc ctttaaactt ctaatccaat aaaaagtagt
    20221 cattacttgt tccaataggt gttcttctac tttatcaaaa tgtactttaa ctatttcttc
    20281 catcatgtct ctatcaggaa attctatata atgaaatatg catcttctta aaaaagcatc
    20341 tggaagttct ttttccgcat ttgaagttat aataactatt ggtctttgtt tagctcttac
    20401 agtttctttt gtctcattta tgtaaaactc cattttatcc aattcccaaa gcaagtcatt
    20461 tggaaattct aaatctgcct tatctatttc atctattaaa agaattactt gttgatttga
    20521 gctaaaggcc tctcctagtt taccatattt tatgtacttg ctaatatcat ctacaccttc
    20581 tcctccaaat tggctatcat aaagtctttg aacagtatca tatacataaa gcccttcttg
    20641 tgcttttgta gttgatttta tattccaaat tactaaatct ttttttaatt catttgaaat
    20701 tgcttgtgct agcatagttt tacctgttcc aggttcgccc ttaatcaaaa gtggcttttc
    20761 aagagcaata gcaacattaa ctgatgccat caattctggt gatactacat aatcactact
    20821 tcctctaaag ttagatatct ctttttttat cataaatcct actcctttta aacagtattt
    20881 tctaaatgta tatagacttt attactattt ttgatataaa aataataata caatacattt
    20941 gtatagt
//
LOCUS       DAEQAF010000062        20781 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.064, whole genome shotgun sequence.
ACCESSION   DAEQAF010000062 DAEQAF010000000
VERSION     DAEQAF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20781
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.064"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            230..1531
                     /locus_tag="KRN00_002466"
                     /pseudo
     CDS             230..1531
                     /locus_tag="KRN00_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            1607..1882
                     /locus_tag="KRN00_002467"
     CDS             1607..1882
                     /locus_tag="KRN00_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1828326.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3325..3555
                     /locus_tag="KRN00_002468"
     CDS             3325..3555
                     /locus_tag="KRN00_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1828327.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3548..4129
                     /locus_tag="KRN00_002469"
     CDS             3548..4129
                     /locus_tag="KRN00_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1828328.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(4707..5384)
                     /locus_tag="KRN00_002470"
     CDS             complement(4707..5384)
                     /locus_tag="KRN00_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1828329.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSNTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5573..6937)
                     /locus_tag="KRN00_002471"
     CDS             complement(5573..6937)
                     /locus_tag="KRN00_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1828330.1"
                     /translation="MKESNKKIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYIARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7065..7586
                     /locus_tag="KRN00_002472"
     CDS             7065..7586
                     /locus_tag="KRN00_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBH1828331.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPETAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
     gene            7718..7855
                     /locus_tag="KRN00_002473"
     CDS             7718..7855
                     /locus_tag="KRN00_002473"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828332.1"
                     /translation="MLNFLRARARARARARARARARARARARARARARARARARAISK
                     V"
     gene            8073..9152
                     /locus_tag="KRN00_002474"
     CDS             8073..9152
                     /locus_tag="KRN00_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1828333.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIAKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINIQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSITIIINGVEKGKLDFELGV"
     gene            9476..9844
                     /locus_tag="KRN00_002475"
     CDS             9476..9844
                     /locus_tag="KRN00_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH1828334.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHEDAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            9961..10758
                     /locus_tag="KRN00_002476"
     CDS             9961..10758
                     /locus_tag="KRN00_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1828335.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPTHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            11157..12047
                     /locus_tag="KRN00_002477"
     CDS             11157..12047
                     /locus_tag="KRN00_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1828336.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKEIIKAYKRSESYTQIKFF"
     gene            12609..13052
                     /locus_tag="KRN00_002478"
     CDS             12609..13052
                     /locus_tag="KRN00_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1828337.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMYALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
     gene            13224..13394
                     /locus_tag="KRN00_002479"
     CDS             13224..13394
                     /locus_tag="KRN00_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828338.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            13767..14864
                     /locus_tag="KRN00_002480"
     CDS             13767..14864
                     /locus_tag="KRN00_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1828339.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIAKGKREEKFNIII
                     KLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            15069..15557
                     /locus_tag="KRN00_002481"
     CDS             15069..15557
                     /locus_tag="KRN00_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBH1828340.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     ITVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            15643..16050
                     /locus_tag="KRN00_002482"
     CDS             15643..16050
                     /locus_tag="KRN00_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828341.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            16051..16269
                     /locus_tag="KRN00_002483"
     CDS             16051..16269
                     /locus_tag="KRN00_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1828342.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            16692..16997
                     /locus_tag="KRN00_002484"
     CDS             16692..16997
                     /locus_tag="KRN00_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828343.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
     gene            17405..18094
                     /locus_tag="KRN00_002485"
     CDS             17405..18094
                     /locus_tag="KRN00_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828344.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSEDMVIQYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            18094..19011
                     /locus_tag="KRN00_002486"
     CDS             18094..19011
                     /locus_tag="KRN00_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1828345.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLLEKFYSRQINYNRSEKAMLQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLVNSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            19084..20010
                     /locus_tag="KRN00_002487"
     CDS             19084..20010
                     /locus_tag="KRN00_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828346.1"
                     /translation="MNYIIETNQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVKPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            20007..20687
                     /locus_tag="KRN00_002488"
     CDS             20007..20687
                     /locus_tag="KRN00_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828347.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSILGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLVFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVVDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTFVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
BASE COUNT         8113 a         2191 c         3599 g         6878 t
ORIGIN      
        1 atatattaat aattggcagt aagttatatc aaataagata ttgctattat gtagtaaatt
       61 atataaaaca atgtatcaga ataaatagta tattaataat ttgtagtata tcatgacgaa
      121 taatacagtc ataacaaata gtgagtcata acaaataatg tatttataat tgataatgta
      181 tttaaaaaac aaaatataaa aacttataag gaaagagaga ttaatttata tgggtaaatc
      241 aaaagatgtt gaaatagaga agtctatttt aggcacaatt cttttagaca ataaattaag
      301 ctataagcta gatgaattaa atgaaaacat gtttatgaat gatatatgtc ttgagatatt
      361 taaaattatg aaagaactta aaaaagaaaa catagtgatt gatgtggcca ctgtgaaatc
      421 aaagatagat agaaaatctc tagcaataaa aacgagtgat gtgactaatc taattacttg
      481 gggtcagaat tttggtcttg atggtcatat taaaatttta aaagaaaatt tagctagaag
      541 aagcataaat caaaactgcc aaaacctttt acacagccta aaccttggag aaaatatcga
      601 tacttgtatt tacaaatttg aaagtaatat aaaggagatt ttggacaagg atacttatga
      661 aaatgatgat gtaaatagta tagcagggaa ggtgcttgat tttttagaaa acaaaaaaga
      721 tattggattt aaatttggta taaaattact tgataccact ataggaggtc tttttaaagg
      781 agagctaacc acaatagcag ctaaatcggg ggttgggaag actgctttgg cacttcaaat
      841 aatgttaaat tcatttaagc aaggtaaaaa aactttattt ataagtagag aaatgaccag
      901 tgagcaagta tttatgagaa atatatgcag agtaactggt gtaagtacaa ggaatatgaa
      961 atctaaagaa atagatgaaa atgattggaa acttattgta aatgctatag gtgatttaag
     1021 cgaaaataac ttaatttata ttaatgataa gatagataca attagtgcaa ttagaaagag
     1081 gataaggcag gtaaagccag atttattaat agtggattat gtgcaactcc ttacatctca
     1141 gaaaagcatg gataagagag aaagggaagt agctactttt tcgagagaac ttaaaaatat
     1201 gactttagat tttaatatac ctgtaatcca attaagtcag ttaaatgatg aaatgaaaga
     1261 ttcaagacct tatggagata gacctatgag ggatagcaaa gccatctacc acgatagcaa
     1321 caatgtggtt tatatacatt aattaaaggg gagtgattat gaagaagcag tgagagatat
     1381 tggagaaagt gaggaggcag ttagagcatc agaatacagg ggaattaaga tggttgattt
     1441 aatagttgcg aagtgtagag atggacagac taggcataag catttttgtt actttgggga
     1501 taagttacat tttcaagaac taaattatta ggtcaataaa gtagtaataa caagcttatt
     1561 aaaagtcggg aaatagcaaa tagattataa aatatgaggt gaaaatatgt tggaattaag
     1621 aaaaattata gaattacttg aagaacacaa gatagaagta agtattccaa aggagttaca
     1681 taagtatagt ttattggaat accttgaatt gtgtcaacaa agtgggggaa catattttta
     1741 tattaaaaca ctggaagggg ctttaaaaga ggctagaaat gagcttatga ttaaattgtt
     1801 taatgggaaa aattatatgg aattagcgag gatgtttgaa atgagtgtta ttaatgtcag
     1861 gcatattgtt agaaaaaaat agatattttt ggagaataca agtgtgatat acttctgaaa
     1921 tagaagttat tatagttgaa ataaaattgt ggttaataaa ttaaagttgt gtataagttt
     1981 aagattatag aggagtataa gtgtgattaa cagcatgatt ttgtgaataa aattgaggat
     2041 atatatgagt taaatgtgtg attaataagg taaggttgtg tataagatta tgagtattta
     2101 aaaggagggg ctataattaa tagtgtagag ttgtgtgttt gcttaagatt atataataat
     2161 ttaatagatt aaactatact aataaggtaa aatcgtgtgt ttagttaaag cttattataa
     2221 aatcttgata tgtgattaat gatgcaatat gtgaataaag ttaagattat aatagattta
     2281 acctgtggct aatagaataa aattgtgaat aaagttaaga ttataatagg tttaacctgt
     2341 gattaataga gtaagagtgt aaatagagat aaacttcaat atgagcttaa cctatgatta
     2401 atagagtaag agtgtaaata gagataaact tcaatatgag cttaacctat gattaataga
     2461 gtaagagtgt aaatagagat aaacttcaat atgggtttaa cttgtgatta atagagtagg
     2521 gtgtaactaa agataaactt caatatgagt ttaacttgtg attaatagag taaggtgcaa
     2581 ctaaagataa acttcaatat gagcttaacc tatgattaat agagtaagaa tgtaaataga
     2641 gataaacttc aatatgggct taacttgtgg ttaatagagt aagagtgtaa ctaaagataa
     2701 acttcaatat gggtttaact tgtggttaat agagtaagaa tgtaaataga gataaacttc
     2761 aatatgagct taacttgtga ttaatagagt aagagtgtaa atagagataa acttcaatat
     2821 gggattaact tgtgattaat agagtaagag tgtaactaaa gataaacttc aatatgagct
     2881 taacctatga ttaatagagt aagaatgtaa atagagataa acttcaatat gggtttaacc
     2941 tgtggttaat agagtagggt gtaactaaag ataaacttca atatgagttt aacttgtggc
     3001 taatagaata agattgtgaa taaagttata gttttagatg ggtattaacc tgttactaat
     3061 agaatatgat taggtgtaaa attatagagc tgtataagaa aatattatag atatattaaa
     3121 tattagataa taaatattta tatagataca caaaagaaaa ggcgatatga agctaaactt
     3181 aatgacttca tatcgttttt tatttgaaac tcctttgtat ttagagtgtg atttttaata
     3241 ttgaggtttt atgtgattaa gtcacagata aaaagtaagt atcttgatat aattcttata
     3301 gattaataat atagggaggt tattatgtct aataaaaaaa agaagtatgc aaatatttta
     3361 gcaaatgagt gcgttgcttg tggtagctgt ataaaagcat gtccaagaag tgctatctca
     3421 gttccatgtg gcattagtgc aaaaattaat agagatttat gtgttggatg tgggatttgt
     3481 gaaaagatat gtccagcatc tgtaattgag attataacaa tattaaaaga ggaagaaggt
     3541 aagtgtcatg aataataaaa aacattggta tgactattta tggatttttt cttcaatata
     3601 tttgatattg ggatttgtaa atattatttt cgcttggatt gggctaattt gtttctttgt
     3661 tccactagct atttctattg ttaagggaaa taaagcttac tgtaataagt attgtggaag
     3721 agggcaactg tttaatttgc ttggaaataa attgaagctg tcaagaaata gagatattcc
     3781 taaatttatt agaagtaagt ggtttagata tgggtttttg acatttttta tggtaatgtt
     3841 tgctaatatg cttttttcaa cttatttagt gtttgaagga agtagaaatt ttaaagaagt
     3901 agtgactttg ttgtggacta taaaaatgcc ttggcaatgg gcgtatcatg gaactttagt
     3961 ttcaccttgg gtggtacagt ttgcatttgg tttttatagt gttatgctta catcaactgt
     4021 tcttggtttg attactatga tattgtttaa acctcgttca tggtgtgttt attgccctat
     4081 gggtactatg actcagatga tatgtaaggc aaagagtaag tctgtataga aaggccttat
     4141 gtgatattta cagttttgtt caagtagaga tgagtagtag gtttgaatat atatgacaaa
     4201 tatatgagta taggggcata gatttagttt gtgtaaggca aactgattta tgcttctttt
     4261 ttatgtctta gattattggc taagtagaaa caatgaattt agatattaag aattattcag
     4321 ttatttgaag aaaatagaat aataattaac attatatgaa tggatattca ttacatataa
     4381 gcagttaata gcaagattta tttaatatga aataggtcaa gtatttaaac taaataaggt
     4441 catgacaatt aatataagta tagatataaa aagattagaa gttataactt ataaaaggta
     4501 ttctatataa gtagtatgtg gaaaatagtc aaattaactt attagaaaca aaaaatatac
     4561 ataaaaaata aatgtaaata tcaaataaga tactatataa aaatagatat aagtatcttt
     4621 tttattattg aaattatgaa aatatatttt attttacaca aaaaagagtg cctcatgaac
     4681 taaaaagttc attttgagac acacttttac agtgtcaaag aacgaagttt atccttatcc
     4741 aatactttta taccaccacg agataaagac acaatacctt ctctagcaaa atatttcaac
     4801 attctcgata caacttctct ggcactaccc atatacttag caatttgttc atgagtcata
     4861 tttatagtgt tactgccatt tttagctatc tcatcaatta aaaaagatgc caaacgctta
     4921 tcaaaactca taaaaagaat ttgttgcata gcccacataa catcagaaaa acgttcggta
     4981 gctaatttat atgaaaataa ctctgcatga atattttctg tagataattt tgcaaaaaca
     5041 gaggaactaa tctgtataat atcgcagtcc gtttcagcat ctacatagac atcaaaagtt
     5101 attgttttta gaatacagga agctgataaa atacatacat ctccatcatc aagtcggaac
     5161 agtgtaacct ctcgaccttc atctgaaagt atgtatgtac gcactgttcc agattttata
     5221 atcaaaatac caatacagtc actatcacca caatgtactg gattcccttt tttgtaatgc
     5281 gaggtatttg ctgaagaaat taataattct ttttgtaagt cagtaagttt atcccaaaaa
     5341 ggcaagctat gtgtaagtat atcaatttca ttttgtgaaa tcatacaata tctcctttct
     5401 taaattgtta taatcccatg atacaagtga atagataaat tgacaagtag tttgttaaga
     5461 ggattattta gtcagatagt aatagtatga tttatgtaga aaaaatatga taatatatat
     5521 tcttgctatt aatgagaaag taatatgttt tgatgatagt aggtttgtat aactaatgca
     5581 taccgtttat ttttaaaaga ttaagttcct tatgtaacct tatagacata aaaccagcaa
     5641 ttatagcagc catcaaatca gctattggtt gtgcatataa gataccattt aacccataga
     5701 atacaggaat aatcaaaatt atagggataa aacagacacc ttgtctacac atacctaaaa
     5761 atccaccttc ctttgctttt cctagtgcga ggaataatgt agaatacact gtatagaatc
     5821 caaatagcat aaatgaaaac ccatttgccc taagagcttt actaccattt tctattaata
     5881 aaatgtcacc acttgtaaat tgtgaaatta tagattttgg gaagagtatc aatataagac
     5941 caagcactac acaaaatact gtagtccata atatggaagt ttttattgct atatgtaatc
     6001 tatcgtagtt ctttgaacca aaattataac cagcaattgg ttggaaacct tttataaaac
     6061 caaatacaac aagactacct aaagacgtta ttcgtgttac agcacccatt ccagctatca
     6121 cagaatcacc atactttgta gcctccatat tagttaatgt aatggcaaga ctagtcaata
     6181 attgaaatat taaggtaggt atgccaattt ttaggatttc tgaaaaaatt tcttttgaaa
     6241 aacagcattc gttaattcta aaactaaata tacttttctt gcttaaaata tatcctacat
     6301 aaacaagtgt tgaagcaatc tgtgagatag ctgttgcaat agaagcaccc cttaccccca
     6361 gaccaaaagt ataaatgaat atcgggtcta aaatcatatt aagcaaagca cctaataaca
     6421 tagcacacat agttgtttta gcagctcctt cacttgtgac aatattagtc atagtgacat
     6481 tgaatatatt aaaaatagat gacacgacat aaatgctagc ataagatatt gcataaggca
     6541 taatactttt tgtagctcct aacaatttta aaattggatt gagaaaaatc ataatcacaa
     6601 taataactaa tgtacccact ataatactac tgtaaataga tgtacttacc acttttcctg
     6661 ctttttcatt atcaccatgt cctaaaagtc tggcaatata tgaagcagct ccatttccaa
     6721 acaataatcc taatcccaca acaagctgac ctaatggaaa tgcaacggat atagctccca
     6781 tttgacttgt tccaagtcca cccacaaagt atgcatcaac caaattgtat aatgcagtta
     6841 tcatcatacc tatcatggta ggtaatccca tagataacaa tgcttttgag attggggcag
     6901 accctaataa ttcaattttt ttgttacttt ctttcatact taacactcct cttctattga
     6961 cattaagtct aaattataat actataaatt atagtaagta tggaaaatag tactataatt
     7021 tatagtattt gtcaatagta agaaaactaa aggagatgat ttttatggct acaatagatt
     7081 taattgtatt gggaatagta aagcaacaac ccaagagtgc ttatgatatt caaaaggcag
     7141 tggaatacag gaatatatca cgttgggtta aaataagtac accatcaatt tataaaaaag
     7201 taattcaatt agaacaaaag ggatatattg aaagtaaaac tgtgaagaat ggaaaaatgc
     7261 cagaaaaagc agtttattca ttaactgaat taggtgagac acatttttta gatttaatgt
     7321 ttgatacatc tagcaaacca ataaatattc ttttagattt taatgctgtt atagtaaatt
     7381 taaatagcct tacaccagaa aaacagaaat tatgtctcaa taatattgaa gagaatgttc
     7441 aagagttaaa gaaaactatt gaggaaaata taagtataaa gacagaagta ccagagacag
     7501 caaaagcagt gttggagcaa cagttggtgc tagcacaagc attggaaacc tggataaatt
     7561 ctttaaaaga taatatgggg aattaggatt agagaagcta acttaataat cattaaacaa
     7621 aaaccagcat atttaataat gagatattag aaaaaataaa acaaatgata taaactgaaa
     7681 agtatattta aaataaagct cacttaattg agggagaatg ttaaactttt taagagcaag
     7741 agcaagagca agagcaagag caagagcaag agcaagagca agagcaagag caagagcaag
     7801 agcaagagca agagcaagag caagagcaag agcaagagca atcagtaaag tataaaattc
     7861 tattactata ataaaagata gaactagaag tctttatgaa agtgggaaaa gtatttatat
     7921 aaataaattt atatggttta tagtttaaca gtaggaaata tcgtatgagt gagaatatcg
     7981 tattttacat aaagatttag caatatgaca cactgttgtc gtgttctgta ggatatgatt
     8041 aataaatcag atatgaaagg agagtgagta atatgccaga attactaaaa aatatgtata
     8101 atcgtgagtc actttatgaa gttgcagtag ctatccaatc agtttacaac tcatttaagg
     8161 tagacgagtt cataaaatct acaatggatg agacatggaa taacttagaa ttaaaagcca
     8221 gatgtcgaaa gataagtatg agtttaggaa tgtatttacc agaagactat aaggaagctc
     8281 tttccattct tgaaaaatca gttacaggtt tttattttgc ttttttcttt ccagattttg
     8341 ttgaagttta tggtcaggac gacataaatt gggatttatc tataagtgca ttagaaagaa
     8401 atactgagta ttggtcttca gaatttgctg taagagcatt tatcatcaag gatgaagaac
     8461 gtatgatggc acagatgcgt aaatggtcta agcataagag cgaacatgta cgaagacttg
     8521 caagtgaagg ttgtcgtccc cagttgcctt ggggacaagc aatatccaaa tttaaaaaag
     8581 accctacacc tgtactgcct atattggagc aacttaaaac agatacatca acgtatgtac
     8641 aaaagagtgt tgctaataat ctaaatgata tctcaaaaac acatccagat ttagtcataa
     8701 gcattgcaaa ggattggtat ggtaaaaata aatctactaa ctggattgta aagcatggtt
     8761 gtagaactct gctaaaaaaa ggaaatcgtg atgtattagc tctttttgga tatgatgata
     8821 ctacttcaat aaatattcag gattttactt tagaaacaac gtctatttct attggagagg
     8881 atttaacttt ttcatttaat attttagcaa aaaaagcgac aaaaacaagg ctcgagtacg
     8941 gaattgatta tattaaatct aatggaaaaa ggaataggaa gatatttaaa atatcggagg
     9001 tttcattaaa agaaaatgag aaaaagtcat atatgaaaaa acattcattt gcagatgtaa
     9061 gtgtaaggaa acattatcca ggtatccact cgattactat tattattaat ggggtagaaa
     9121 aaggcaaact tgattttgaa ttaggtgtat aattttacta acagcataac ctatatcaga
     9181 tactttgcta aacctatatc atatattcta ataaatctat attagatagt ttactacttg
     9241 tttactaaat ttaaatacaa agaaatacag gtgctaatcc ctgcccatta aaggaatatg
     9301 agcataacac aaaagtagaa cttatcaatt ctgttacggg tatagtagta aatccataga
     9361 atcacaatta gaagatgaag tgtaaaaaat aagttagtgt tgattttagt tgctagtgat
     9421 attgaatagt tatacaatag ccatataaat tagaatttgt agaggagaaa tgtaaatgga
     9481 tgtatatagt ttttggaatg acactttggc acaagatgct gttaagataa gaaaatattt
     9541 tcatgaagat gcttatatta attggcatga tacaaatgag cattttactt tagaagaatt
     9601 tattattgca aattgtgagt atcctgataa atggaatggt aaagtagaaa aggtgctaga
     9661 atttggaaat ttagtaatta cagtgacaca tgtttatgca ataaataaac cactatcatt
     9721 tcatgtcgtt tcatttatca gccttaaaga tgataagatt atttctattg atgaatattg
     9781 gggagaggat gatgatgtgc cacagtggag attagataaa catattggaa agccaataaa
     9841 atagtgtttg ttctgtttta taactgaaat tttgataaca tttgatattt tgatttgtca
     9901 ttggtcaaca tagtcgttag tgtaataatt taaaaaagta gaatttggag agtgaacact
     9961 atggaagaaa aatacatctt atctgaccga gggaaagtat attattggat aaaagaaagt
    10021 aatagtgtgt ttgcaaagaa cttaattttt ttgccaggac taacagcaaa tcatcatctt
    10081 tttgatttcc aaatacagta cttttcaaaa aatcataatg tattggtatg ggacgctcct
    10141 actcatggaa aatcaagacc ttacttagat ttctcatatt ctaacttggt agaagaattg
    10201 aaagtaattt tagataaaca aaatatgaaa aaggttgtac ttatagggca atcggcaggg
    10261 ggatttgtgg cacagtcctt tattgtaaaa tatccaaata tggtagaagg attaatgatg
    10321 attggaactt gtccatatgg aactgactat tatagtaagt cagatatttt ctggttaaaa
    10381 cagactgaat ggatgttaaa gttattccca gataaatttt tgcgaaacat aatatctaag
    10441 atgtgtggag ctacgtctga aggcagaagg agtatgctga aaatgttaga aggctacgaa
    10501 aaaaaagaac tgtgtcatct catgtatctg ggatttgctg ggttcatacc agaaattcaa
    10561 gacttaaata tacattgtcc agtttgtttg gtggttggag ataaagacaa gacgggtaaa
    10621 gtgagaaaat ataatgagca gtggcacaat aagactgggt atccattgca cattataaaa
    10681 aatgcttcac ataatgtaaa tgtcgataaa cctaatgaac taaatcagat tatggatata
    10741 tttattaagc aattataata tataaaaatt acatacccat taggtaaatt atgtagtata
    10801 tgtgtttaca gatggttata gaaataaata tgtaataaac tacttaacac ttaaaaagtg
    10861 gatttgtcca gagcataata caaagcatga tatatataaa tttttaagcg aaatacatca
    10921 aaagaaggat tagaattagt ggagacagaa cagctattat agattataaa taaatagttt
    10981 taaaggagag gtactacgaa tatagaggaa ggtaaatcat acgttattca agtattataa
    11041 atgattagtt taaaagtact atcggatagg agtctccata tttaaacctt agtaaaggta
    11101 gttaaagtag tagtttaaaa actaaaaaat tatataaagg aattaggtat aagaaaatga
    11161 ttgagagtat accagcaaaa caaattttac aaaaagtgaa atttgacaat acaagatggt
    11221 ttggaattga ctataatatg aatctctatc gtggttgttc tcatggatgt atatattgtg
    11281 atagccgtag cacaatatac aacatagaga attttgacaa agttagatat aaagaaaatg
    11341 tgatagaaat tttaagtaaa gaattgcgtt caaaaagaaa aaaaggtgta gtaggcattg
    11401 gagctatgtc tgacacatat aatccttttg aaaagcaact ttgtattaca aagcaagcac
    11461 tagatttgat ttcggaaaat cattttggag tgtctattga tactaaaagt agtttggtgg
    11521 ttagagatat accgattttg cagaaaatta aaaaaaataa ttctgctatt gtaaagttga
    11581 ctataaccac tgcaaatgat gaattatcaa agaaaataga accttatgta aatccaagtt
    11641 ctgtacgatt tgaggcagtg aaagaactta atgattctgg aattttttgt ggtatattat
    11701 tgactcctat gcttccattt ttgactgata ataaagatga aatacgagca attgtagaaa
    11761 aagcacacaa ggctaatgca aaatttattt attgcatgta tggtgtaaca atgcgtagtg
    11821 gtcagcgaga gtttttttat gagcatttaa gagatatatc accaaaattg gtacttaaat
    11881 atcagaaaac atatggttta aactatgtat gtactgtaca aaataaagat tgttgtgaga
    11941 agttgttaag agaagaatgt gcacgttatg gtattttgac ggatatgaaa gagattataa
    12001 aagcgtacaa gaggtcggag tcatatactc aaataaaatt tttttaagat aggctttgga
    12061 tgagatataa tagtggtgat tgatgtgttg atattatagt tgattgttag agaggatatt
    12121 atagatgaat attagtattg atattttagg taattgctag agctgatatt atagatgaat
    12181 attagtattg atattctagg taattgctag agttagtatt atagatgaat attagtattg
    12241 atattctagg taactgctag agctaatatt atagatgaat attaatattg atattctagg
    12301 taattgctag aactaatatt atagatgaat attgtattga tattctaggt aattgctaga
    12361 gttagtatta tagatgaata ttagtattga tattctaggt aactgctaga gctgatatta
    12421 tagatgaata ttagtattga tattctaggt aactgctaga gctgatatta taatttatta
    12481 ttagtattaa tattctaggg aattatcact atattttaaa aagtaaaaat atatatcaaa
    12541 atgaactaaa taagtactgt aagaagtttg ttaaattaag gtttgaataa agtgagggtg
    12601 gagaacttat gatagaaata aaaactatag aaataaataa aaaaagtcaa attgaccttt
    12661 taatgttagc cgacccatgt gaagaaatga ttgataaata tctcaataaa ggaactatgt
    12721 acgcattgta tgataataaa gaacttactt gtatagcagt tgtaaatgaa atttccaaag
    12781 aaatatgtga attaaaaaac attgctacat atgagcattt tcaaaatatg ggttatgcct
    12841 caaagatgat ttatcatctt ttagatgttt atagtaaaaa atattcatca atggttgttg
    12901 gtacatctga aagcggagtt cctttttatg agaagtttgg atttgtttat tcacataaaa
    12961 ttaaaaactt ttttgtagat aattatccag aaccaatctt tgaaggagaa ttacaatgtg
    13021 ttgacatgtt gtatctatca tataactttt agataggata atatttttag gttaatataa
    13081 ttaattaatt catataatta tcggaattat aatttataaa ttatgtataa taagagtata
    13141 atttatttag aagctgttat attgtattat attcaaataa gatatataat aacttgttta
    13201 ttttgaattt tggaggatta attatggatt caaataataa tactataaaa tcaactgtta
    13261 aaaagggtat ttcttttggt tcttgtttag caatgattat ttcttatact gcatggaaat
    13321 ctattccatg ggctattttt catggcttaa tgagttggat atatgtactt tattattggg
    13381 ttaagtatgc atagattaaa ttaataaata agtatgtaat attgtaaagt ttaagaaaca
    13441 aaatgtaagg gagtgtctcg aagtgaactt ttagtttata aggcactctt ttttgtatta
    13501 aataaaatat attttcatta tttaaacaat gaaaaagatg agtatctcta ttttaataca
    13561 tacccttata ttcattcatt tatcaacaat agttttaaaa agaaagctat ctaaaatcta
    13621 ttgtaatcta agtgcttctc tttaaagtct taactttagt aatgatatat aagtttataa
    13681 ggttcttatt tcaataatgc aaattttact tagaagttca gactttggta tgaagaaatg
    13741 ggtaataata aaaaagaggt gttgatatga aagaaaaatt agaagaaaaa tctaagatta
    13801 ttaaaacatc aaaagagtat aaacgaacta taattgaaga aaaggacaga gaatggacca
    13861 aaaaattaaa tgacatactt agtagaggtg atttttctaa tgaaaaatta gataaaatca
    13921 aggatttaat tccaaaagaa atattgacta gtgaaaatgt tggagaagtt gtaactgaag
    13981 atgggtatgc taagcctgag tatgatgagg tatttaaatc attgtttact ttaaataatg
    14041 attacgattt acttgcaaat tttataaatg atatcctcaa agatgctcca tatgctaata
    14101 ggaatatcaa acagttcact caaataaaaa gaataattaa ggttgaaacc gacccaacaa
    14161 ttaattacat tggtgagaaa agacctagac ttgatatttt ggctgaagat gaagaacgta
    14221 accatataaa tattgagatg caaagagctc ttgaagagga ttatttggaa agagctgaat
    14281 attatcttag tcgtgtacat ggtagaaagt tagaagaagg taaagaatat aaagaaattg
    14341 gaaaaactgt tggaatacat atactaaatc atgtaaaata taatcacata gaagattatg
    14401 taaattgcct gagattaaca atggacgggc atccagatat ttattctagt aaaactgcat
    14461 tatattttat agaacttcca aaaattcgta aatccagttg tatagcaaac agagttctaa
    14521 tatggggtaa acttattgat aatccttctc atatagatat tagaatacta tctaaaacgg
    14581 attatgttat taaaagagca cttgatagat taaaagaatt aggtagtaat gaggactatt
    14641 tattaaattt aaagagaggt gcgtatatta tgaataaaag tagaaatttt aaagaagaaa
    14701 tttttcaaga aggtattgaa aaaggtattg caaaagggaa aagagaagag aaatttaata
    14761 tcatcataaa attaaaaaat aaaggataca atttgagtga aatatgcgat attatagatg
    14821 atttgaataa atcagaggtt gaaaaagtct ataatcaaaa ctaatactat gattgagatg
    14881 gcactagata aatacaaagc ttcctctttt aaatttaaat taatataaaa ctttgttatt
    14941 taaatatggt agatataaag agatatataa ataataggta caaagaggtg tataaataaa
    15001 ggagataatt caaaataaaa gtttgaacca tctccttctt atagaaaaac aaaggggttg
    15061 atttatatat gaaattttat actatacaga ctttagaatt ttggaataac aataaaaaca
    15121 ataaatatct atcaaatgat tattctttta tattagaaga ctttgatatt ccatacaaat
    15181 ggatgtatag tcaaatgaca aatagaatat atgaatttga tgatagtatg atatgggttt
    15241 ggacgaagag acctgattta agatgtagtg gttatttaga aaaaggaaaa aaaggtgttt
    15301 tacttgaaat agaaataagt gaagacaatg tgttattatc agaatttgat ttatggcatt
    15361 tacctttaat ggatattact gtagagcttt atgaagatga acaaattgaa aagaaggtaa
    15421 gctgggaaag aatatttgac ttagaactgt gttcaaaatt aaatgaagtt aatatagaag
    15481 atttgacatt gcaaggagtg acatctaaag tgcctctatc taatgtaaaa ttaataaaag
    15541 aatttgttgc aaaataatat ttttattgaa atttattcaa aaaagttata tatttataac
    15601 aagaggtgtt ataaatacat aactttttaa gggggatttt atatgtctaa acaacaaact
    15661 ggtattaaat caacacttat ttcagaaata ttgggaattt cttattgtat tggagctaca
    15721 ttagtaaata agtatttttt taaaggaagt agtattgaat atcttcctat aattatttgg
    15781 gtattagcta tgggagctca gtgggtctat aataaaaagt atgatgattt aattgatgag
    15841 gcatcaaaat gtatactatc aagagttaat gatattgcaa taaaagtatt gtttttttct
    15901 gtagctatag tatctatatt tcttgtaact ttggacataa atgtgtcaaa tttaaatata
    15961 ggaatgtctt tattagtcat tttgtttatt caatccttgt tgaagttaat tctatttata
    16021 tattttgaca gaaaggggat atacaattag gtgtcagtat tactaaagac aaaaattaaa
    16081 tcctatagag aaaagaacct tatgacacaa ggtgaacttg caaagtcagt aggagtaaga
    16141 cgtgaaacta ttgtacattt agaaaatggt cgctacaatc cttctttaaa actggcaatg
    16201 gatattgcta aggtatttga tacaactgta gaagagttgt ttgaatttat tgaagaaaat
    16261 aatatttaaa tttcatgtat tacttatgca ttagagaatg aattaattat aggtaaaaaa
    16321 ccaagcttat agattagaga ataaatgact tatagatgaa aaaccaagct tatagattag
    16381 agaatgaatt aattataggt aaaaaccaag cttatagata agaagtccat gcttataagc
    16441 cagaaaatga atactttaat agattaaaaa atacatattt gtgaattata gaatgaatga
    16501 ctccataaac tagaaaattt ataataatat ctatatgaaa attagaatta ttttatcaca
    16561 aaaaaattaa gttaaataaa tatgaaatta cttccaaata tacttccaaa aacatgtaat
    16621 tgcatatata atataattat aaaaataata aatattttta tagtagtagt taattataag
    16681 gaggggtcaa aatgcctagc atgattatgg aagttgtagg agtactattt atagctattg
    16741 gattaatctt gacattcatt gaaataaaag gaaatttccc ttctttttat ggttttggtc
    16801 aaaattctat agggaaaaat gctgtaggta ttatagcagc aggaattgct ttaattttct
    16861 ttagaaatgg catagatagc atagattcta tagctactta tggtgtattt ttagcaatag
    16921 aacttgttgt aatagttgca tatttcttaa taagaaaaaa atttactaaa gaagataaac
    16981 atttaagaac taattaacta aattatctac tataaaattg gaaaattaaa aacaaataaa
    17041 agtttgtttt taattattta aaatccaaat ttgattattt ttaaagaaac tatgttctgt
    17101 ataaaactag aatgtggttt cttttttatg tataaaatat tttttagcaa aagttaaaag
    17161 gtgttttata atataaaata gttaattgta gatgttaata aaagaaaatt atgtatattt
    17221 cagataaaga taagagagta tactatattt taattctttt ttcaataaag cttattgaaa
    17281 agaactttaa cttagaagag tatcaccaaa ttgcagatac aatatcataa gcagttattt
    17341 attgacaacc ctttttaata aatatatcat ttgaagtata ctgacgaaaa ggagttgaat
    17401 aataatggac atcttattgg ttgaagatga taagaatatt cgagaaatgg tatacgattt
    17461 tctgattagt gagaattact ctgttaaaac tgccattgat ggaaatacag ctattgaaat
    17521 atttaaaaat tattcatttg atattatttt actggacttg atgttaccaa agtctagtgg
    17581 ttttgaagta ttaaaatata tacgaagtgt gagtgttgtt cctgttatta ttactactgc
    17641 gaaagatagt gacacagata aaatgctagg gcttaatctt ggtgcagatg attatattac
    17701 aaagcctttt tcaatcgtag aattgcttgc aagaattaaa gctaatatta gacgtgcaac
    17761 agtgtacagc agttcaagaa actctgaaga tatggttatt cagtataaag atttgattat
    17821 aaacatatca aaatatgtag tttcaaagaa tggaattgac ttaaacttaa cacatacaga
    17881 atttgaaatt gttaaattac tagcgactaa tcaaggacgt gctttttcaa aggaacaatt
    17941 atacaacgct atttggaaag aaccttatta tggaaatgaa aatgtgctaa atactcatat
    18001 taacaggtta agaaataaat tgtctgatgg tatagaaaaa aataattata ttaaaactct
    18061 ttggggaatt ggctacaaaa tggaggaaga ataatggagt tatttttagt tgtaatttcg
    18121 attgtactat ttgctctcta cttaaaagaa cgaaataaat caaagaaaat ggaaagtgat
    18181 tataagtata tcaattcaag acttcgtgac ataacaaatg atgatgaaat taattatatt
    18241 ttagtaccat ctgatatttc gattgtaaaa gaaacagcag tagatataaa taaacttctt
    18301 gaaaagtttt acagcaggca aattaattat aatagaagtg aaaaagcgat gttgcaaata
    18361 tttacaaaca tatcacacga tttacgaact cccatcacag tattaaaggg ttatattgaa
    18421 atgttatatc ttcaaagtca aaaagaagaa ttatcttctt caatgagagc aactgtggaa
    18481 aaaatgcaaa caaattcaaa tgagcttgtt aattcaataa ataacctgtt taatatggca
    18541 aaaatccaat ctggagatat gatattaaat cttcaaaaat ccaatctaac acaattatgt
    18601 catgagatta ttttagagtt ttatgatttg ctagataaag aaaactttaa tgttgaagtt
    18661 aatattgaag atagacctat atatgcaaat gttgacacag aagcattaca acgtatactc
    18721 aaaaatttaa ttgataatgc tataaaatat ggttcagatg gtagattttt agggatttca
    18781 ctatatgaaa aggaaaaaca tgtttttata gatattgagg ataaaggttc aggtatttct
    18841 gaaactgaaa aagagcatat tttcacaaga gcttatactg ctgacagaaa aaaaggcaat
    18901 ggtttaggtt tggctatttc tcaagggctt gtaaactcta tgggaggttc aatttatgta
    18961 aatagtagac ctaatgtaaa aacagttttt acagtaaaat tgaaaagtta gaaaaaagtt
    19021 agatttaaaa gagagaaaag ataattttat tttgtatact gtttttagaa aggagggagt
    19081 atgatgaact atatcataga gaccaatcaa ttaaagaaaa tatataaaga taaagctgtt
    19141 gttaatgctg ttaatattca tgtgaaaaag ggagaaattt atggatttgt tggaccaaac
    19201 ggggcaggta aaagtacagt aatgaaaatg ttgctaaatc ttgttaagcc aaattctgga
    19261 gaaatagtta tgttcggtaa gaaagtggca gaaactgatt ttgaaatatt aaaaaagatt
    19321 ggtactatta ttgaaaatcc gtatttatat gagaatttga ctgctaaaca gaatcttgat
    19381 ttacactgtg aatatatggg ttattataac aaagaacata tatcagaggt attggaatgt
    19441 gtcggattgt caaagcaatc aaacaagaaa gtttcaaaat attctttagg gatgaaacaa
    19501 cgtcttgcaa tagctagagc aattcttact aaaccagaat tattgattct tgatgaacct
    19561 ataaatgcac tcgacccaga ggggataaga gaaatgcgag aattattccg taagttaaat
    19621 acagattatg gaataactat atttatttct agtcatattc tttcagaggt agaacaaatt
    19681 gcggacacta ttggaattat tcaagatggt aaacttatta aagaaatttc tatgtcagat
    19741 atacacaaat atcaaacaga ttatgttgaa gtagatgtag ataatgtgga gcttgctgga
    19801 tacttgttag aaaaagaatt tggaataaaa gactttaaaa ttacttcgga aagttgtatt
    19861 gaaatatatg atttacgaaa agatgtaaaa gaaatatcca aaatatttat tcaaaatcaa
    19921 attggtataa atagcattgg acgtaaacaa agttctttag aagattactt cttccaaact
    19981 acaggtacag gaggtaaaga aacactatga tacatttaat gaaactagag ctaaaaaaag
    20041 ttgggctaaa aagatatttt ttattttcaa tactggggat tttcttatgt atgttttttg
    20101 tctttactgg attgaatgat aaatctactt caatatatga ttatgatgtt acatttagga
    20161 caatcagttt agttttctgt ttttactata ttatattatt tgctgtgttg aatgtggcat
    20221 atataataaa tgaatataca aataaaacaa tcttgatttt attctcttat ccacttgacc
    20281 gtaaaaaact tattttatca aagttacttt tgattacgac tcttatgata tcatcaatga
    20341 tagttggata tatctgttgt tttacattcg ttgttgtggt ggataagtat tttaatttag
    20401 ttattggaga ttttcatatt tcaattttat cttattggat accaggagca attaaaagta
    20461 ttattgtatt ttgctcatta ggtatatgga cattcgttgt tggaatgata agaaaatcaa
    20521 tacctgttac ccttgtcagt tcaattattt ttatcaattt aagacaattt attttagctg
    20581 gtacaaatac aactcaagac agtttgattt ctgtttttat tatagttggt ataactgtga
    20641 ttggtatata ttatatacta aatcataaag ttactgaaat tgactagata ctgtggctag
    20701 gaaggtagtt attaattgta tcttcttggg ataataatga tttgctatta tatcagctat
    20761 tattaatatt attagagttt t
//
LOCUS       DAEQAF010000063        20737 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.065, whole genome shotgun sequence.
ACCESSION   DAEQAF010000063 DAEQAF010000000
VERSION     DAEQAF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20737
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.065"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..840)
                     /locus_tag="KRN00_002489"
     CDS             complement(<1..840)
                     /locus_tag="KRN00_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1828348.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(1101..3143)
                     /locus_tag="KRN00_002490"
     CDS             complement(1101..3143)
                     /locus_tag="KRN00_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBH1828349.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRDFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(3295..4266)
                     /locus_tag="KRN00_002491"
     CDS             complement(3295..4266)
                     /locus_tag="KRN00_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBH1828350.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVVESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISRNHFVACHLV"
     gene            complement(4267..5244)
                     /locus_tag="KRN00_002492"
     CDS             complement(4267..5244)
                     /locus_tag="KRN00_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828351.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVSFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTVGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            5463..7022
                     /locus_tag="KRN00_002493"
     CDS             5463..7022
                     /locus_tag="KRN00_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1828352.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEGYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAKIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            7128..8087
                     /locus_tag="KRN00_002494"
     CDS             7128..8087
                     /locus_tag="KRN00_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828353.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            8090..8902
                     /locus_tag="KRN00_002495"
     CDS             8090..8902
                     /locus_tag="KRN00_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828354.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIITSFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(9118..10020)
                     /locus_tag="KRN00_002496"
     CDS             complement(9118..10020)
                     /locus_tag="KRN00_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1828355.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIAFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            10375..11553
                     /locus_tag="KRN00_002497"
     CDS             10375..11553
                     /locus_tag="KRN00_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBH1828356.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLSKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            11562..12218
                     /locus_tag="KRN00_002498"
     CDS             11562..12218
                     /locus_tag="KRN00_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBH1828357.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            12218..12883
                     /locus_tag="KRN00_002499"
     CDS             12218..12883
                     /locus_tag="KRN00_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBH1828358.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            12988..13764
                     /locus_tag="KRN00_002500"
     CDS             12988..13764
                     /locus_tag="KRN00_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBH1828359.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGVTGQACLLDGGYTAQ"
     gene            13826..15160
                     /locus_tag="KRN00_002501"
     CDS             13826..15160
                     /locus_tag="KRN00_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBH1828360.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMGAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            15656..16582
                     /locus_tag="KRN00_002502"
     CDS             15656..16582
                     /locus_tag="KRN00_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBH1828361.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPNNNKPESNKPEDNNNSGSTDKPDNNKPESNKPEDN
                     NNSDSTNKPDDNNNSGSTSESFSAYQKEVVDLVNIERAKAGLNPLTLDSSISNVATKK
                     SQDMIDNNYFSHNSPTYGSPFDMLKKFGISYKTAGENIAMGQKTPKEVVNAWMNSEGH
                     RKNIMNPNFSKIGVGVAQKSGGSIYWTQIFVG"
     gene            complement(16974..20513)
                     /gene="nifJ"
                     /locus_tag="KRN00_002503"
     CDS             complement(16974..20513)
                     /gene="nifJ"
                     /locus_tag="KRN00_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBH1828362.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPANT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMDICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
BASE COUNT         7166 a         3252 c         2914 g         7405 t
ORIGIN      
        1 taaattcagt acagatataa ctcttttgat atgtaatgtt aaataaagta gttcatcttg
       61 acttacatag taatcataat tcttttctac atgagttttt attttatatg cacaatcata
      121 atccttttca tactttactt taattatatc tataatttca ttatttgtat catttatttt
      181 ttcttttttt actaatcgtt ttgcaaagaa ttttaaatga gtcagaagcc tatcataatt
      241 tatatcatct tctttaaatt caactctata ataatatctt ataatattta gtatgtcttt
      301 tacaatttta gtaattaaca gtgattcctt tgaacttccc ttatagtttg aatttactat
      361 atgcattgct ataaaaccag cttcatctac tggaaatttc acatcaaatt ctttatttat
      421 ataatctaca gcccatttcc caatctcata ttctttttta tgtattcttt ttatctcatg
      481 tagtaaatca ttctttatag ttatgttttc atgatatctt ttaattgcaa atgcaatatg
      541 gtcagtaagt gctacataaa tatattcata aagcttagta ttcaaattct cctctgcata
      601 agcaattatt tcagtactaa cctcaaaaaa tttctcatca acctggcttg ctagtttact
      661 aattttatct aaaaagcttt catcttgtat tacaaaagtt ctttcaattt tacttttatc
      721 tatttcttga cctttctttt tttgaaaccc aattccacat cctgttaata ttaattcttt
      781 ttttatattt tcatctaaaa ctaatacaac attattatta taaatttgtt gaataatcat
      841 aatcaatatc tctcccaaaa tacaatttcc cttattcata aaaaaatacc taaattaaga
      901 tacaattcac ctgtatacct taacctaggt attgcctgct taccagtaac aatccagctt
      961 gttaatgctt atatattgta ttcaatttat ggttttattc tattataaat aaatatatat
     1021 gtcaagtaaa ttattgaaaa ctatttccta ttttttagta ttaattttaa catcaaaaat
     1081 caaattttat tccattatat ttatgattct atcatcatca tttcatcata gagaatattc
     1141 tccaataact ctttagccac ttctcttgat atttgcttag tttcaactaa ttgttgaaca
     1201 ctgtctcttt gactttgtat cgccattact ctgtagtatt ctactcttgc ctcaaactta
     1261 tcatcatttt gaatctttct agtaatccaa ttcaaataac gattatagaa tctgattgct
     1321 attaaggcct catgtctgtt atcttcatca gtatttttat ttataaatga tatagcagtt
     1381 ttagtagaaa gtgcatatgc atggtgaaac tctttgatta tttctttatt ctcagatact
     1441 atttttgtaa ttttttcttt tacttctttc tttacttttc tatttataat ccacatgctt
     1501 atttttaatt ttacaatttt aaatatagat ttttgaacag attttcttga ttttgtaata
     1561 taaaatctat acaatttaaa gtctctatca gaaattttac catcttctaa tagtttcaaa
     1621 acagctaata atccctgttg gtctgcttct gcaatcatca tacttataag tttattatct
     1681 ggagtattta gtattccttt ttctgagtct accaactgtt catttaaatc atgtataact
     1741 ggttgtactt cttgtgcttt ttcattacta agttttaaaa tggcttcttt caaaattagt
     1801 ttatatgcct ctttatcaga taataaaggt tctgactctt gtacgttatt ttttaataat
     1861 cttggcagta aaactgttgc caatactaaa cttataagaa taacttctga tgatataaat
     1921 aaaacagtat ctctcattgg aaatacatct ttatcagcca aataaaaagg tatagataag
     1981 gcagttgcta gtgtaaatgt accatgaaca ccacaagtag caactattag tgagtattta
     2041 catttagaaa tactctcttt tacaacttct tcatccttaa aacctaaaaa acctacaaaa
     2101 aaattattta aaggattctt tttaggtttt ataaaagaat tatgccataa atatacccat
     2161 ataaatctta taacaaataa aataagtaca attaaagtag aaataaaagt caattccaat
     2221 gccatatttt catttttact actaagtcct gtatatatac ttggtaacaa aaaaccaagc
     2281 agtgtaaaga caaatccatt caatacatac tccaaaacat accaagtatt atctgatatt
     2341 atccttaatt tagtagttgt attttgtaaa tgctcttttt caattccatg agctatccct
     2401 gccattacaa cagctaggat tccagatact cctatttctt ctgctacaaa atatacaaaa
     2461 agtggagtca ttatttgtat aactattacc attggaattt cttccaaatt ccacttgtgt
     2521 aaactaagtc ttatttttat aattatgtat cctaaaatac ttcctactat tattcctcca
     2581 aaagctgtaa tcataaattg aatccctgcc tcttctattg aaaaaactcc tgtaactgtg
     2641 gcaagtactg caaccttaaa tgctactact ccagcagcat catttaataa agattcacct
     2701 tcaagtatac tcatcatatt tttaggaaaa tttaatcctt gtgtaattga ttttactgct
     2761 actaaatcag ttggagatat tactgctgcc aaagcaaatg aaacagataa tggcatccca
     2821 ggaataagaa aatgtataaa gattccacct gcaaacacgg ttattaaaac taaaccaaat
     2881 gcaagaagca aaattggttt tctgagctct aatagctctt ttctcgatac attttgtcct
     2941 tcactgaata gtaatggagc tatgatacat attacaaata tttctggatt aaatgaaaat
     3001 gagaatttaa atggcaaaat agacaatata atccctagta caatttgata tattgcaaga
     3061 ggaatattac tccacttttt gctaaataca gttgaaatcg ttgtacaaac caataatccc
     3121 aacaatgtta ctaaaattga cataactacc tctcttttca ataataatat tatagattaa
     3181 acttatatat caactaactt aatattaaca gcatgaaatc ccatcttaat caaaaaaatt
     3241 ttcagtttat tctattattc ttattatata catcaaattt aatttttgaa atatctatac
     3301 tagatgacat gcaacaaaat gatttcttga tatttctttt aaaactggaa tctctttttt
     3361 gcatatttcc ttacaataag ggcatcttgt atgaaactta catccacttg gtggatttgt
     3421 tggagatggt atgtctcctt ttaatataat tctatttttc ttaattgtag ggtcttgtat
     3481 tggtactgcg ctcataagcg cttttgtata tggatgttga gaatgtaagt aaagttctcc
     3541 tttagttgca atttctatta tagaacctag atacataaca caaactctat gtgcaatatg
     3601 atttactaca ctcaaatcat gagatataaa taaatatgaa agtttatatt tatcctgtaa
     3661 atccataagt aaatttataa tttgagattg aatagaaaca tctagtgcag aaacaggttc
     3721 atcacaaact ataaattctg gatttaatgc taatgctctt gctataccta ttctctgtct
     3781 ttgacctcca gaaaactcac ctggttttct atttaaatgg tacttagaaa gaccacaact
     3841 ttctacaaca tttaatatat tatcttttat ttcattcttt ggcactaaat tatgttctat
     3901 aactgcctcg gatattattt gttccacatt taatcttgga tttaatgaac tatatgggtc
     3961 ttgaaatatc atttgcattt tgggtcttaa ctttctaagt tcttccttct ctaacttata
     4021 tatatctaca ccattaaatt caactttacc ttcagttttt tcaattaatc taagaatggt
     4081 tcttcctgca gttgattttc cacatcccga ttctccaact atagccaaag tttctccttt
     4141 ttttaaatca aaagaaattc catctactgc ctttacacat ttaatttcct tatcaaataa
     4201 tccagattta acttcaaagt actttttaag accttctact tttaataaac tctcttcttt
     4261 tttcaattat atctcctcct ttttatataa ccaacatgca atactatgac cactattcaa
     4321 ttctattaaa ggaggtatct gagttctaca tttatcacat actttttcac atctatcact
     4381 aaaataacat gaatctggca ttccaattgg atttggtact tgtcctggaa tcgaatacaa
     4441 tcttttatct ttgttttttc caagagcagg ctttgatttt agaagtccaa tagtataagg
     4501 atgttttgga tttttaaata attcaacaac ctctgccact tctataattt taccagcata
     4561 catcactaat actttgtcac acatttctgc aactactccc aaatcatgtg taatcatcat
     4621 tatagatgtg tttaattttt cttttatatt tttcattata tctaaaatct gagcttgaat
     4681 agtaacatct aaagctgttg ttggttcatc agctataagt aattttggat tacatgataa
     4741 agccatagct atcattattc gttgtctcat accacctgat aattcatgtg gatatgaatt
     4801 atatatttct tcagctcttg gtatttctac cagttttatc atatcgatta cctttttctt
     4861 agcttcttcc tttgataaat cttgatgtat cataatacct tcaatgattt gacttccaac
     4921 agtaaacgct gggtttaaag atgtcattgg ttcttgaaaa atcattgata tctcattccc
     4981 tcttattccc ataagttcat cttcattcat ctttaaaatg tctttgcctc gaaagattat
     5041 ttctccacct tctatttttg atgttggaag taacttcatc aaagacatgg ctgttacaga
     5101 cttaccacat cctgattctc caactattcc aatagtttca ccttcattta tattaaaact
     5161 tacttcattt acactcttta caatcccttt atctgtatga aaataaactt ttaaatcttt
     5221 aacctcaatt agtgctttac tcattatttt ctcctctcag caaaattact taagataaca
     5281 tacacctttt gattgtattt tataaaaatt taaattacaa cattttctta cattttatta
     5341 tttttttcta ttaattataa taatataata gttaatttct atatatattg atttaataat
     5401 gattactatt atacaataaa aaatatgtgt taaatattat tttatggagg ttttataaga
     5461 atatgaaatt taaaaaattg gcatcattaa tcttagtttc atcattaatg cttacattta
     5521 cagcctgtgc ttccaatgat aaagacaagt ctagtggaag caaatctggt ggaactgttg
     5581 taatacctat ggcaagtgac ccagatataa tcaatggagc ttttgcaaac gttaaagaag
     5641 actctcttgc atcaaatata gtttatgctc ctctttatac ttatgaaaaa ggaaatttag
     5701 taaattattt agcagaaaaa gtagatttta aagatagtaa ggaattaact ataaaattaa
     5761 aatccaattt aaaatggcat gatggaaagc caataactgc tgaagatgtc ttatttacat
     5821 ttaatacagt tttagacgaa aaacaaaatt caccatcaag acaatactta ttggtgggtg
     5881 agaaaccagt taaagtagaa aaaattgatg atttaacagt taagattact ttaccaactg
     5941 caagtgaatc tttcttatat ggtatatcta aaatttctcc aataccaaaa catgtgtttg
     6001 aaggagaatc aaatatagct aagtcagaaa aaaataataa tccagttggt tctggtgcat
     6061 tcaagtttaa ggaatggaaa aaaggtgaaa gcatagtatt tgaaaagaat gcagattatt
     6121 ttggtggaga acctaaggca gattctatag cgctaaaaat aattcctaat gaagcatctc
     6181 aagaagcagc tttaaataat ggcgaaattt cacttatgaa gacatctgct gaaggatatg
     6241 aaaaggcaaa atcaaactca aacttacaaa cttatactta tagtgaagaa agattaaact
     6301 acattgtatt taaccaaaat atatcaaaca tggctaacaa agaagtaaga caagccttat
     6361 catatgcctt aaatagaaat gaaatgatag aatcagcata tggaaaagaa ggttctgtac
     6421 ctgctaaatc tatattagtt ccagaagcag acttctatac agaagaaggt gttgaaggat
     6481 atgaccaaga tacaaataag gctaaagact tattggataa aagtggtgtt aaaattgata
     6541 aattaaaaat aggttataac acaggtagat ttgggcataa aaactatgcc ttagtagctc
     6601 aacaagagtt gaaaaaaatt ggtatagaag ctgaaatagt tccttatgaa agtaaggcat
     6661 tcttcaatat actatttagt aatagcactg aatgtgatat gtatgtaaat ggttatgctt
     6721 ggggattaga accaaaccca tatagaggta tgtttgaaac tggtcaatat tgcaaccaaa
     6781 ctaaatattc taatgctaaa atagatgctt tatgggaaaa aggatttact gagttaaaca
     6841 aggaaaaacg tgaagaaata tataagcaaa tacaacagga tatatctaag gatgcgccta
     6901 tttacactat agattatgaa caaaatttaa tggcagctca aaaaaatcta aaaggaataa
     6961 aagatgctaa accatctcct gcaatattat ttgaagattg gtctaaactg tatgtagaat
     7021 aattgatgta aaattttata ttattaatta gaaaaggaga tgtctaaaaa taatattgtt
     7081 ttattatttt aaaacgagac atctctttta attaggagaa tttacttatg ttaaaattaa
     7141 tattgaatag agtaaaagtt ttaataccta tgttaatctt aatatctata ttatcatttg
     7201 gacttttaga attagctcct ggtgacccag cagatgcata tataaatcct ttaatgtctt
     7261 cacaggatat tgaaaatata agggttaata tggggcttga taaaccagta tatataagat
     7321 atttaaactg gttgaaaaac actttaagtg gaaacttagg tatttcttat ataaaccata
     7381 tgcccgttac agaacaaatt atggaaaaaa tgggaaatac atttattctt atgggtactt
     7441 ctttgatatt ttcaatattg gtagctatac ctcttggaat atttttagct gtaaataaaa
     7501 attcaataac tagtaaagta tcatctgttt ttaattatat aggtgtttct ataccttctt
     7561 tttggatagg tatgatactc atttcaattt tttcagttaa acttaacatt ttcccatcag
     7621 gaggtatgca tactattgga aatgatagta ttggagattt agtaaaacat ttagttttgc
     7681 ctgtaataac tttaggtcta tataatactg ctatttttac aaattatgta gaagctagtg
     7741 taaatgaaca attaaaaaaa caatatgtta ttacagcaag agcaaaagga ttatcagaaa
     7801 aagtcatact atttaaacat gtcttgaaaa attcactgac atcattggtt acaatcctag
     7861 gcatgagtat acaaaaatta gtcactggtg catttgttac agaagtagtt ttctcttggc
     7921 caggtatggg aagattaatg attgattcaa ttttttcaag agattatact gtaattatgg
     7981 caataactat gttatcagca ctatttttaa ttttaggtaa tttagttgct gatatactat
     8041 acttattaat tgaccctaaa ataaaatcta gcaaaggagg attctagttg tgtttacaag
     8101 tatcttaaaa aaattaaaaa aagataaatc ctttgctttt gcatgtatta ctcttagcat
     8161 aataatcata ttaattataa cttcttttat attaaatata gactctaatg caattgatac
     8221 tacttctaaa cttcaagaac ctagcttaaa gcatatcttt ggtacagacg aacttggtag
     8281 agattacttc tctagagctc tttatggtgg aaggatttca cttagtgttg gtattttatc
     8341 aatgcttatt tctgtagtat ttggtactgc tgtaggtgtt attagtggat atattggagg
     8401 taagctagac caattcttga tgagattagt ggatatgctt atgagtatac caagtttctt
     8461 agttttgatt gtattaaata cttatctaac acctaaagtt tccactatta tactaattat
     8521 tggattctta agttggatgg aagtttcaag aattgtacgt ggcgaaacat taaaaataaa
     8581 ggaaaatgaa tactgtctag ctgctaaagc tactggtatc aaaactagaa atatactatt
     8641 aagacatata gttttaaact taaaagagac tattgtagtt gctggttcgt taaatattgc
     8701 taatgctatc ttaactgaat ctgctcttag ttttttaggt cttggaatcc aattgcctct
     8761 tgcatcatgg ggtaatatgc ttcaagatgc tcaaagacat atttttgaca agttatattt
     8821 agctgtattt ccaggattac ttatattttt aacagtcatg agtttgacta taataagcaa
     8881 aaaattttct agtaatactt aacaaatttt atatagaaaa taaaaacagt gattatctaa
     8941 agatatacac tgtttttatt tttcgtttaa aaaaatacat attttgtata ttataacttt
     9001 aaatactact ctaccatgtt atgtaaagcc tattattgct ctcaaacata tagatgaaaa
     9061 actaatagtt tattataata aaaattgatt tatttatttg ttattttaat aacattttta
     9121 agagttcttt ttactaaaga aatctataat aaatttaaat acatgttggt ctacatggct
     9181 ataacgttct tttttaggtc tacataatat aactttccat gtaataggat gattaaaagg
     9241 cttttctata attttgctat tttcaaaaaa atcatgaact ggtgatggta gaattgttat
     9301 aaaatcagaa tttgtggttg atagcaacaa aaaatcccat gaaccagaca ttatatatct
     9361 ttttaactta acattttcat cagtaaattt ttgcattagc ttatgatgta tcataaaagt
     9421 aggattaaat attgcaagta actgctcatt caaatcgttc caatctatct tatccttctt
     9481 agcaagtgga tgatttatat ttaaaaatgc tgtaagttca tcttcttgaa gcacatgttc
     9541 agttactaca cttttatcaa ttttatgtgg atgtaacaat actgcataat ctaattcctg
     9601 taagataagc attctattta agtcatatgc acccttctct actatatcaa attctatatc
     9661 tggattattt gcaactaact gtgcaactac atctgaaaat gctattccaa gtataagtgg
     9721 aggtattcct attctaactt ttcctttaaa ttgaactgaa tcttctctta aatcttccat
     9781 catatttttg tattcattta tgatatgttc tgcatttaca taaaatcttt ctcctgctgg
     9841 tgttaaccca tttaacctac ctttatacct ttcaaataaa tatacatctt cactttcttc
     9901 aaaatttttt ataatttgac ttaatgctgg ttgagatatg tgaagtgtct tagatgctat
     9961 tgataaatta aaaccagatt tcactatttc aacaaaatat ttcaactgtt ttatatccat
    10021 tttaaacccc cttccccaaa agtataattt agattatatt ttttcttcta atgatatttt
    10081 ataggaaaat caacataatt tcattaatat tttaacaaaa tatttttcta aatctactat
    10141 aaatttttat cctataaatt tttcttatac actatataaa aaattagact tagacaaaat
    10201 gcttttttcg ccgtaatcta taattagaaa caggaaaacc taaagcatta ggaataaaag
    10261 taattgaaat acttaaaaac aagcttgtat taaaaaagta ctttattata gtgttcccta
    10321 atttctttat tcagaaaatt tttaattatc attcaagaaa ggtaactatt agatatgaaa
    10381 gatgtagtaa tcgtatcagc agtcagaaca cctataggaa gttttggagg tgtatttaaa
    10441 aatacttcag ctgttcaact tggaactatc gctgttaaag aagcgatatc acgtgtagga
    10501 cttaatttat ctgaaataga tgaagtaata attggaaatg ttcttcaaac agggcttgga
    10561 cagaatgttg ctagacaaat tgctataaat gcaggtatac caaattctgt tccaagctac
    10621 acagtaaata aattatgtgg ttcagggctt aaaagtgtcc agctagctgc ccaatcaatc
    10681 acatctggtg aaaatgatgt ggtaattgca ggtggtactg aaaatatgag tcaagctcct
    10741 tatatcgttc caactgctcg ctttggtagt aaaatgggta acataaccat ggtagatagt
    10801 atgctaacag atggtcttat tgatgctttc aatcagtatc atatgggaat aactgcagaa
    10861 aatattgcaa ctaaatttga atttactaga gaaatgcaag ataaattggc attagaaagt
    10921 caaaataagg ctgagaatgc tataaaaaac aaccgcttta aagaagaaat cgttccagta
    10981 gatgttttaa tacgtcgagg aaaaatagaa actattgata aagatgaata tcctaaatta
    11041 ggtatgacat ttgaaggttt atctaaactt aaacctgcat tcaaaaaaga tggtactgta
    11101 acagctggaa atgcctcagg tattaatgat ggtgcggcta tgttaatact aatgagccaa
    11161 caaaaagcag acgaactagg tattagacca cttgctaaaa taaaatccta tgcttcagct
    11221 ggtgttgaac ctgaagtcat gggtactggt ccaatccctg caactagaaa agcactgaaa
    11281 aaagctggac ttagcatcaa tgatatagac ttaatagaag caaatgaagc gtttgctgcc
    11341 caagcattag ctgttaaaaa tgaacttcaa atagattcat caaagttaaa tgttaatggt
    11401 ggtgcaatag cattaggaca tccaatagga gcaagtggag ctagaatact tgttacctta
    11461 atttatgaaa tgcaaaaacg taaagttgaa actggacttg caacactttg tattggtggt
    11521 ggtcaaggaa tatcaatggt ggtttcacga taggaggaaa tatgaataaa atagttagca
    11581 ttgatgaagc tctatctcat gtaaaagatg gagatacaat aatggttggt ggattcatgg
    11641 ccaatggttc accagaaaat ttaattgatt atttatgtag taaaaatata aaagatttga
    11701 cactaatttg caatgatact ggctttattg acaaaggagt tggcaaaatg gttgtaaata
    11761 agcaatttaa aaagataatt gcttctcatg taggattaaa taaagaaact ggaagacaaa
    11821 tgaataacaa tgaaacagat gttgagttag ttcctcaggg aactcttgct gaacaaatac
    11881 gtgcagctgg ttatggtcta ggaggtatac tcacaccgac tggtattggt actcttgttg
    11941 aggagggaaa gcaaaaaatt gttgtcgata gcaaagaata ccttcttgaa aaaccaattt
    12001 atgcagatgt tgctcttcta tttgcatcaa aggtcgataa agcaggtaat ctagtttata
    12061 aaggctctat gaacaatttt aataatttaa tggcatctgc tgccaaaatt acaatagttg
    12121 aagcagatga aatcgttgaa attggtgata ttgacccaaa tgaagttaat acaccaggta
    12181 tttttgtgaa ttacatcgtt gaaggaggta atttataatg gataaattag aaatgcaaga
    12241 atatattgca aatagagtat ctaaagaatt aaaagacgga gccgttgtaa accttggaat
    12301 aggtctacca accaaagtag caaattatat tccggataat gtaaacgtta tcttacaatc
    12361 tgaaaatggc tttttaggtt taggttcagc cgaagatgga aattcaagtg atgaaactat
    12421 tgtaaatgca ggtggtcaac cagttactat acttcctgga ggatgtttct ttgatagtgc
    12481 tacttctttt ggaataatca gaggaggtca tgttgatata actgttcttg gcgcacttca
    12541 ggttgacaaa tacggcaata tagcaaacta tatgattcca ggtaagatgg ttccaggtat
    12601 gggtggagct atggacctag taactggagc taaaaaagtt attgtagcaa tggaacatac
    12661 ttcaaaaggt tctgcaaaaa tattaaataa ttgtactctt ccacttactg caacaaatgc
    12721 tgtagatttg atagttactg aaatgggagt tatggaagta acatcagatg gaattttact
    12781 taaagaaata aatccagctt tcacattaga tgatgttatt tctgctactg aagctccttt
    12841 aatattgtca gattcattaa atggaaaaat atctgttgtt taaaataatt aaaactagaa
    12901 aataaaaatc tcttagacgt attacatata aatttgtatt gcttaaaata ttaatataaa
    12961 aataaaataa aattggagga aatgaaaatg gttaaagata aagttgtatt cgtaacagga
    13021 gctgcaagtg gaataggtaa acaaatagct gaatcgttct taaaaaatgg tgctaaagta
    13081 atgttctctg atataaatca agaagcttta aataatacca taacagagtt acaaaaaaaa
    13141 ggatatgatt gcatgagtgt aaagtgtgat gtaactaagg aagaagaaat taaccacgct
    13201 atagacaaaa ctgttgaaaa gtatggcaga ttagatatat taataaacaa tgctggactt
    13261 caacatgttt ctatgataga agatttccca actgataaat ttgaatttat gataaaaata
    13321 atgctgacag caccttttat agctactaaa aaagcatttc ctataatgaa aaaacaaggc
    13381 tttggtcgta taataaatat ggcctcaatc aatggtgtaa taggatttgc tggaaaggct
    13441 gcttataact cagcaaaaca tggacttatt ggactaacaa aagttgctgc tcttgaagct
    13501 gccgattctg gtataacagt taatgcttta tgccctggat atgtagatac tccacttgtc
    13561 agaggtcagt tcaatgacct ttcaaaaact cgtaatatac cattggaaaa tgtcttagag
    13621 gaagttttat acccacttgt accacaaaaa cgcctattag atgttcaaga aattgccgac
    13681 tatgctatgt tcttagcaag tgataatgct aagggtgtta caggacaagc ttgcttacta
    13741 gatggaggat atactgcaca atagttatta tatttagggc ttgaagaaag tattcttcag
    13801 gtccttctac taaggaggga tatttatgag tattatcgcg ccaattggta taattattgg
    13861 tatcatagct attatatatt tttcagttaa agaaattcat ataactatag ctgctccaat
    13921 agcaacttta atagttgtta ttttaaataa aatggatgtt gtaacgtcaa tgctaggtgc
    13981 tgacaaaaac aattatatgg gtgcacttgg aaactatata atgagttatt ttgcaatatt
    14041 cttattaggc tcaatacttg ctaaatttat ggaagaaagt ggagctactg tatcaatagc
    14101 tgattttatt ttaaataaat ttggctctaa tcatccttat agagttttag ttgctatatt
    14161 tatagtaagt tttatattaa cgtatggtgg tataagctta tttgtagtta tgtttgcggt
    14221 cattccactt gcaagaactc tatttaaaaa acttgatatt tcttggaacc ttattcagat
    14281 accactttgg cttggtattg caacaattac tatgactata attcctggaa caccagccat
    14341 tcaaaatgtt atacctattc aatatctaaa tacgtctctt actgcagcta ctataccaag
    14401 tattgtaggt agtataggtt gtgctacgtt tggacttgtc tatatgaaat atgctctaaa
    14461 caaaagtatt agaaaaggtg aaacttatgc aacttatact tcagaattag aagaagaatc
    14521 tttagataga gaattaccag gattttttgc aagtattttt cctctattag cactcgtaat
    14581 tatagctata actggaagta cttttggttc agaatttatg aaaaaaaatg taatttacat
    14641 agctttaata gttgcaattc ttttatctgc ttttttattc cataaatttc tatcatctaa
    14701 gatacagaca ttgagcatag gtgctagtgg ttctataggt cctatatttg ctacatcttc
    14761 tgcagttgca tttggagcag taataatggg tgcacctggt tttgatgtat ttagcaaact
    14821 tataatgtca ataccaggta gtccacttat aagtcttact gttttgactt caacaatgtc
    14881 agcaataaca gggtcctctt ctggtgcatt aggaatagta atgccaaact ttgcagatta
    14941 ttatttaagt actggtctaa atccagaatt aattcaccgt gttgctacaa tagcttcaaa
    15001 tatactaact atagttccac aaagtggtgt ttttcttaca ttcttaagct tatctaagtt
    15061 aacacataaa actggattta aagaaacttt cattgtagtt gcagttggtt cactaatagc
    15121 agaaattatt gtaattacat taggattact aatgtattaa tataaaacaa attaaaattc
    15181 ataatatgaa aggtggtgtc tcaaagtgaa ctttttactt aatgagacac tctttttata
    15241 tgaaataaca tatgcctatc atttcaacaa taaaaaaggc cttatctcta ttttgagaca
    15301 gacccttttt atttcttaaa gatttaaata attataattt gttgctaata cgaaagcatc
    15361 tactgaataa atttaaccaa ataaaaaaaa atttatcata actataaatt tacgttatgg
    15421 aattattata aaaatattat tttctctaac taagtaattc catactatac aggcttttaa
    15481 tacaaattgt caaacacact gaaatatacc tatttattcc atatatatct tttttacata
    15541 tctttacagt aaaaaaagtc ttaatcttat gttagtatag attcacgggt acccccctac
    15601 actaaaagtt acaaatcagt aacattttta gaatttttag attaagaggt gtttaatgat
    15661 gagaagaaat ataccaacaa aattaaaaac tatattagct ttaggagtgt taactttagc
    15721 aacagcttca agtgctgtta ctgcaagtgc ttcatcactt gaaaataatg taaatataag
    15781 taacaaaagt ttagtatata gtaatactaa atacaagttt tctgcaaaac caaattgttc
    15841 tgtaaaacca gaacttaagc ctgataaaga taactcttgt aaggataaga atcataatga
    15901 caagaattgc aacaacacta ataaacctga ggacaacaat aattcagact ctactaataa
    15961 gcctgataac aataaacctg agtctaataa acctgaagac aacaataatt caggctctac
    16021 taataaacct aataataata aacctgagtc taataaacct gaagacaaca ataattcagg
    16081 ctctactgat aaacctgata acaataaacc tgagtctaat aaacctgaag acaacaataa
    16141 ttcagactct actaacaaac ctgatgataa taacaactca ggctctacaa gtgaaagttt
    16201 ttcagcttac caaaaagaag ttgttgactt agtaaatata gaaagagcta aagctggatt
    16261 aaatcctctt actcttgatt cttctatatc aaatgttgct acaaaaaaat ctcaagatat
    16321 gattgataac aactattttt cacacaattc tccaacttat ggttctccat ttgacatgtt
    16381 gaaaaaattt ggaataagct ataagacagc aggtgaaaat atagctatgg gtcaaaaaac
    16441 tcctaaagaa gttgtaaacg catggatgaa ttctgaaggt cacagaaaaa atataatgaa
    16501 tccaaatttc agtaaaatag gtgttggagt agcacaaaaa agtggtggtt caatttattg
    16561 gacacaaatc tttgtaggat aaaatactct ttttccatac atatcaaaag agtatctcta
    16621 agtgataaaa aacacaaatg agatactctt ttgtatctat tttaaaatta tcaaatccaa
    16681 atatacatac tataaatatt atttgttctc ttaattttag tgtgtagaac aatatataaa
    16741 aagtattggc aagatgaaaa tggaaaactt aaaaaagata tttaataggt aaaaacaaaa
    16801 tcttaatatc ttcataaaaa aaggctgtct caaaatagag ataagtcctt tttcattgtt
    16861 gaaatgatta aaatatattt gatttcatac aaaaagagtg cctcatgaac taaaaagctc
    16921 actttgagac actctctttt atcaatttat ataagcatta taatacttta atattattca
    16981 gctaattttt tgtatccttc atatctttct ttagcatcag cttcagcttt agcaaataat
    17041 ccatcagctt cttctgggaa ttgtttagct atagcagaat atcttacttg tgcaagtatg
    17101 aaatctttga agcttgcagt tggttctttt gaatctaaag tgaatgggtt tttaccttca
    17161 gcttttactt ctggattgaa tctgtataaa tgccagtatc cgcaagcaac agcttgtgct
    17221 tcgttagcta cagttcttcc cataccttct tttaatccat ggtttataca tggagcataa
    17281 gctattatta aagatggccc atcatgtttt tcagcttcta taacggcttt gataaattgg
    17341 tttttatcag cacccatagc aacttgagct acatatacgt ttccatatgt catagccatc
    17401 attcctaaat ctttctttct agatttttta cctgaagcag caaacttagc catagcagca
    17461 gctggagtag ctttagaagc ttgacctcct gtatttgaat atacttctgt atcaaataca
    17521 agtacattta catcttcacc agatgcaaga acatggtcta atccaccgta accgatatca
    17581 tatgcccaac cgtctccacc tagtatccat tgagatctct taactagata atcttttcta
    17641 tcttttatag cttttactaa ttctttagct ttttcatctg tacaatcaca agctggtttt
    17701 tctaataatt caacaacctt agcacttgct actttagaag cttctccatc atttctagaa
    17761 tctaaccact ctgtaaatac tgctttagca tcttcacaga tatccataga aactaactct
    17821 gtcatagcat ctactatttt atttcttatt tgcttaacag ctgtgtacat accaaatcca
    17881 tattcagcat tatcctcgaa taaagagttt gcccaagatg gacctttacc ttcatggtta
    17941 caagtataag gaattgatgg tgcagaagct ccccatatag aagaacatcc agtagcatta
    18001 gctatcatca ttctatctcc atataattgt gtaactactt taatgtatgc agtttctcca
    18061 catccagcac atgctcctga aaactccatt aatggttgtc taaattggct tcctttaaca
    18121 gtgtttgcag gcataacatc accttttgga gctacctcat caggatttac tgcaaatgcc
    18181 caattatcta actctgtatc aagttgagta tctattggct tcataactaa agctttttct
    18241 ttagctggac atatgtcagc acagtttcca catcctgtac agtcaagtgg actaagttgc
    18301 attctatatt ttaatccttc taatccttta cctaatgctt ttttagcttc aaatccttct
    18361 ggagcattag ctaattcttc ttcagtaact aatactggtc ttatacatga atgaggacat
    18421 ataaaagaac attggttaca ttgaatacag ttatctatta tccattcagg aacatcaaca
    18481 gctataccac gtttttcata agctgcagta ccacaaggga atgttccatc ttctatacca
    18541 ttgaatgtac ttactggtaa gttgtttcct tcttgtgcag tcattggtct tagtatattt
    18601 tttataaatt ctggttcttt aacttctcct ttatctgcat caacagcatt ttcccaagaa
    18661 gctggaactt caactttaac taaagcattt attcctgcat caacagcagc atagttcatg
    18721 ttaactattt tttcaccttt tttaccataa gctttaacta tagaatcttt taagtattta
    18781 acagcatctt cttctggtat tatttcagct aatttaaaga atgcagattg cattatcatg
    18841 tttattctgt ttccaagacc tatttcttgt cctagtttaa cagcgttaac tgtatagaat
    18901 tttatatcat ttttagctat atattgtttc atatgagctg gtaaatgttc ttcaagtcct
    18961 gcttggtccc atatagtgtt aagtacaaat gtaccacctt ttttaagacc ttttaataaa
    19021 tcatattgat aaacatatga ttgtttatga caggcaatat aatcagcttc atctattaaa
    19081 taagtagctc ttattggagt atcaccaaat cttaagtgag acatagttat accaccagat
    19141 tttttagagt cataatcaaa gtaagcttga gcatattttt cagtatggtc accgattatt
    19201 ttgatagctt gtttattagc tccaacagta ccgtcagaac ctaatcccca gaacttacat
    19261 cttatagttc ctttagaagc tatttttatt ggctcagatg gagttaaaga agtattagtt
    19321 acatcatcaa ctatacctac tgtaaatcca tttttaggtt gttctgaaac taagttatca
    19381 aaaacagttt ttatatctga aggagtagta tcttttgaac ctaatccgta tcttccacct
    19441 attatcatag gagcattttc ttttccatag aatacatcac gtacatctaa gtataatggt
    19501 tcaccagttg aacctggctc tttagttcta tcaagtacac atattctttc aacagtagat
    19561 ggcatagcat ctaagaaatg tttcattgag aatggtctat ataaatgaac tttaactaaa
    19621 ccatattttt ctcccttagc atttaagtaa tctatagttt cttctattgt ttctgttact
    19681 gaacccatag ctattaatac gtatttagca tcttctgctc catagtaatc aaataaacta
    19741 tgttttctac ctgttaaatt actcattttt tccatgtatt tttcaactat acctactata
    19801 ttttgatagt atttattaga agcttctcta gtttggaaat atatatctgg gttttgagca
    19861 gtaccacgag caactggatg atttggagat aaagcattat ctctaaatgc ttgaactgct
    19921 tcaaagttta ataaacttgc ataatcttca ttttctagta attcaacttt ttggatttca
    19981 tgtgaagttc tgaatccatc aaagaaatgt ataaatggta atctaccttc tattgcagct
    20041 aaatgtgcaa caggtgctat atcagctact tcttgaactg aaccagaagc taataataca
    20101 catccagttt gtctagcagc cataacgtct tggtgatccc caaatattga taaagcttga
    20161 gatgctaaag cacgagcact tacatggaat actcctggta acaactctcc tgcaacttta
    20221 tacatgttag gtatcattaa taataaacct tgagatgctg taaaagtaga agttaaagct
    20281 cctccttgta aagaaccgtg gaatgttcct gatgcacctg cttctgactg catttcaaca
    20341 acattaactg tttgtccaaa tatatttttt cttccttgtg atgcccactc atcaactact
    20401 tcagccatag ttgaagatgg tgtgattgga tatatagctg ctacatctgt aaacgcatag
    20461 gcaacatgag ctgcagctgt atttccatca agtgttttca taaacttagc cataatatgt
    20521 atcctccttg atagctacaa ttgtacttgt ttataacaag tctatttttt tatatttaca
    20581 tataatttac acaacaaaaa tataaacaca catatagtcg cgcaaatact ctatcttcta
    20641 atataatact acagattaga taaaattcct ttgaaaattg taaattaatt acatatttaa
    20701 gtagattttt tttaaaatta aatatgttaa gtttttt
//
LOCUS       DAEQAF010000064        20717 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.066, whole genome shotgun sequence.
ACCESSION   DAEQAF010000064 DAEQAF010000000
VERSION     DAEQAF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20717
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.066"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            121..1152
                     /locus_tag="KRN00_002504"
     CDS             121..1152
                     /locus_tag="KRN00_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBH1828363.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLELLASRNHWNSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEYNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFNIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            1285..2583
                     /locus_tag="KRN00_002505"
     CDS             1285..2583
                     /locus_tag="KRN00_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBH1828364.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKEAYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLPHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(2697..2942)
                     /locus_tag="KRN00_002506"
     CDS             complement(2697..2942)
                     /locus_tag="KRN00_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBH1828365.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            3090..3956
                     /locus_tag="KRN00_002507"
     CDS             3090..3956
                     /locus_tag="KRN00_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBH1828366.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(3960..4496)
                     /locus_tag="KRN00_002508"
     CDS             complement(3960..4496)
                     /locus_tag="KRN00_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBH1828367.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(4687..4890)
                     /locus_tag="KRN00_002509"
     CDS             complement(4687..4890)
                     /locus_tag="KRN00_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH1828368.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            5181..5945
                     /locus_tag="KRN00_002510"
     CDS             5181..5945
                     /locus_tag="KRN00_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBH1828369.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKKTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            6334..7647
                     /gene="prdC"
                     /locus_tag="KRN00_002511"
     CDS             6334..7647
                     /gene="prdC"
                     /locus_tag="KRN00_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBH1828370.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQRRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      8050..8135
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            8717..10897
                     /locus_tag="KRN00_002512"
     CDS             8717..10897
                     /locus_tag="KRN00_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBH1828371.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDVEKPSDGQIPDVEKPS
                     DGQIPDVEKPSDGQIPDGEKPSDGQIPDGEKPSDGQIPDGEKPSDGQMPDGEKPSDSQ
                     TPDVEKPLDEQTPEEEKPLEEEIVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEED
                     VKADEQSEINQVFTSEDSFISLWYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTL
                     TFDYVIKGLVGASSKDDKYVIEGEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQE
                     NQNEEAVKSILYAGSEFDGFGYKQQFNLGEEENDIMTYSATQSAIWIILGQIDEQERL
                     KQYQGSIDLCDKLIERAKTEEERAEYQKRKEVAINTKAYLEALLKAGREELRPNDTGK
                     PSLSNGLTKINFEKNEDGTYETEAVALVGYSGVVKLKLPDGVTAYDVDGNIIGTGEVE
                     ISTQQKFKLKSVGKPDAKANISAVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQN
                     LLSYTIEKKNGQEVNFNIGLPTDDDDVVNPPVPPIDDDVVNPPVPPTDDTNGHKPKPS
                     PPIDDTVINPPVPPMDDTIINPPVPPTEDAVLNPPVPPTDDTVLNPPVPPVSDTVEKT
                     PELSRDDTIVKSPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
     gene            11304..13064
                     /gene="prdR"
                     /locus_tag="KRN00_002513"
     CDS             11304..13064
                     /gene="prdR"
                     /locus_tag="KRN00_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBH1828372.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            13493..15373
                     /gene="prdA"
                     /locus_tag="KRN00_002514"
     CDS             13493..15373
                     /gene="prdA"
                     /locus_tag="KRN00_002514"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBH1828373.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            15454..15738
                     /locus_tag="KRN00_002515"
     CDS             15454..15738
                     /locus_tag="KRN00_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828374.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            15776..16501
                     /gene="prdB"
                     /locus_tag="KRN00_002516"
     CDS             15776..16501
                     /gene="prdB"
                     /locus_tag="KRN00_002516"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:16226..16228,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBH1828375.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            16581..17339
                     /gene="prdD"
                     /locus_tag="KRN00_002517"
     CDS             16581..17339
                     /gene="prdD"
                     /locus_tag="KRN00_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBH1828376.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            17354..17821
                     /locus_tag="KRN00_002518"
     CDS             17354..17821
                     /locus_tag="KRN00_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH1828377.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            17839..18321
                     /locus_tag="KRN00_002519"
     CDS             17839..18321
                     /locus_tag="KRN00_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBH1828378.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            18341..19348
                     /locus_tag="KRN00_002520"
     CDS             18341..19348
                     /locus_tag="KRN00_002520"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBH1828379.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            19468..20349
                     /locus_tag="KRN00_002521"
     CDS             19468..20349
                     /locus_tag="KRN00_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBH1828380.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
BASE COUNT         8271 a         2404 c         3827 g         6215 t
ORIGIN      
        1 atatatggtg tacttatttt atgtttttag caagaaatat agcatttaaa agataaattg
       61 tgcaacttaa atcaaagttt aagatgaact attaacatag atatattaaa aacttttgta
      121 atggagaata tatgtgatat gaataataaa gttaaggttg cagtattaga tacaggaata
      181 gacaaagaac atgattactt aaaagataat ttagttggag gaattgcttt tgaatgtatg
      241 catgattata tctttatatc agataaattt gatgatgaag atggtcatgg aactgcttgt
      301 gcatcaataa taaagaaaga gtatgaagat gtagagttat ttgtaataaa aattttgaga
      361 aaagatggta ttacaaatat aaaagttctt gaagaagcat taagatacct tttagacact
      421 aacataagat taattaatct aagtttatca gtcataggag tagaaagtgt taagggctta
      481 tttgaagttt gttatgaatt gtttagaaaa ggaaaaataa tagtatgttc actcgctaat
      541 gattttgact taagttatcc agctatgttt aacaatgtta taggtgtaag aggatttact
      601 ttagatggag atgattcatt ttggtacaac aaaaaatatg atgttcaatg tgttatggat
      661 agcaattcat atataagttg tgacataaat aattcctata gattaccacc aaaatgtaat
      721 agttatttat cagcaaagct tactggtaaa atagctaaga tattatcaga aaaaccaggc
      781 ataacaatat ctgatttaaa tgataagctt gaattattag caagtagaaa tcattggaat
      841 agttgtgatt ttgatgagtg tagtagaatt gtaaacttta aattggattt gtatgacaaa
      901 gaaaatgctc ttcttatgaa agttgctgac gttgttaggg attgtttaga tattgaatat
      961 aataatgaaa aactctttaa gggtagcctt tttaataagg agataggctt ggtttatgat
     1021 aattgtttta atttgttgaa aaagctagag catagattta acataaagtt taattatatg
     1081 gacatctcaa aatatgactt agtttcaata tatacactga ctgaattagt ggaaagatat
     1141 aaaaacttat aaataaagat ttgtagctaa atttaatgta gaaggtatta aattatatgt
     1201 attctttgtc agtagattaa aagtaaaaaa tatactataa ttagatagca taagagaaaa
     1261 tgccaataca gggggagtta gataatgaaa tatgaagaag cattagagta catatcacaa
     1321 actaataaat tcggtataag attaggatta gaaaatattg gaaagttatt agaattatta
     1381 ggaaatccac aagaaacttt gaatataata catgtagctg gaactaatgg aaaaggttct
     1441 gtgtgttctt ttgtttctaa tatactaaga gagtgtggat ataaagttgg tttatataca
     1501 tctccatatt tagaaacttt tactgagcgt ataagagtaa atggacaaaa tataccacag
     1561 gatgatgttg ctagaataat tgagttaata aaagaaaaaa tagagattat ggtaaaagaa
     1621 ggctatgcat atccaacaga atttgaagtg gttactgcaa tggcatttta ttactattca
     1681 gaacaaaagg tagattttgt ggcattagaa gttggtttag gtggcagata tgatgctaca
     1741 aatataataa caaaatcact tgtaagtgtg atagtatcta taagtttgga ccatacaggt
     1801 atacttggag atacaataga aaaaatagcg tacgaaaagg ctggaataat aaaggaaaat
     1861 ggagtagtac tagtatatga ccagactgat gaagcaaagg atgttataaa gtcagtttgt
     1921 aaagagaaaa aagctaaata tatagaagtt gattttgatg atataaacat aaaaaaatca
     1981 gatataaatt ctcaaatata cgattgtact gtaatgaaag aagcttatag agaccttgaa
     2041 ataaaattga taggcgaaca tcaaataaac aattctatct tggcaattag tgtaataaaa
     2101 tatctaaaag acataaataa attagcaaat ataaatgaag aatctataag aaaaggactt
     2161 ataaatacta aatggccagg aagaatagaa aagataaagg aaaatccaat ttttataata
     2221 gatggtgcac ataatgaaga tggagcaaaa tctttggcaa aagcacttga taagaatttt
     2281 aaaggtagaa aattaacatt attaataggt atgttagaag ataaagatat tgatagtgtt
     2341 ttagagatat tgttgccaca ttttaataag gtaataacaa caacaccaaa taacccaagg
     2401 gccataaatt cagatatatt aagagaaaaa gtattaaaat atgtagatga tgtaacatca
     2461 aagcatgaga tagaggatgc agtaaattat acattagaaa catcaagtga ggatgatatt
     2521 ataataagtg caggttcatt atatatgatt ggtacagtga gaactttagt aaagaaatta
     2581 taattttata aaataaatat acaaataaaa atataaaaaa gagttgtcta aaaaatggac
     2641 aactcttttt atataaaata agtttttaat aattttactg atgtttatat aagtaattat
     2701 atagattgac gtatagcttt agataattgg tctgggcaag aagtaccttt tccaccacag
     2761 tcaataccat ttaatttatc agcaacttca agagcatttt ggccaattat taagcttcta
     2821 agtcctgata aattaccatt acatcctcct ataaactcag catcaacaat cacattattt
     2881 tcatcaactt caaaaatcat ttctctacaa catacaccac ttggattaaa tgttactttc
     2941 attaaaaaga cctccattaa atattatttc tttttttaac attaataata ataccaaata
     3001 tatgcgtaat aatgcaacta taaagcataa tacaagctaa tgaaataata tattattgta
     3061 gtatatgtat tgtagagagg aggggttata tgaaaatcta tatttctaac tacttatcaa
     3121 agagtattag catagttgat tattctacac ttgaactaga aaaagaaata gtattagaag
     3181 ataatatata tccacaccat ttttgcatag aaaaagaaaa aaatttaata tacataccta
     3241 gttcaagtaa tgggatactc tatgtcttag atttaagtaa tgataaaata attgatactg
     3301 tctctatagg aggaagtctt agtcaagttg tacttagcga taatgaattg tttgtggcaa
     3361 atgaagattc taatagtata tatgtactag ataaaaacac attaaatcca ataggaatta
     3421 ttggagttga taatatgcca catggatttg actttgatag agaaagcaaa aagttatatg
     3481 taccgtgtat aaactcgata gtatgtatag atacaattaa taaaaatata caaaagaaaa
     3541 taaatatgga ctttagagct tggcatatag aacttgataa acaaaagaaa gaaatgtata
     3601 tatcaacact tgatggaaag cttataataa tagatgaagt aagcatggat ataaaaaagg
     3661 tattatatga atttttatta ccagtagaaa taagatttaa ttatagtggc aaaaaagttt
     3721 atgttgctga tttgggttat aataatgtaa gaattttaga ttatacaacg agtagataca
     3781 ttggaaatat tgaaataaat gggattcccc aaggattaga aatatctaaa gatgaaaagt
     3841 tactatttgt atcagataca caagaaaatt cagtaaaagt ttatgaaact gcaaataaca
     3901 aattaataaa agaaatcaag gtaggaaaag agcctacaac tataatttgt ttgtaggctt
     3961 taatgtatgt ctcttataag taaatcgata acttcggcat acatataaga tgcattattt
     4021 ttccagttat tgcaaataag ttttgcttgt ttctctgatg aaacatttag atttaaatct
     4081 attaagttag actgattttc tatgactcta aggttgacaa taaattcatt atcactttgt
     4141 tttacaaaac tagactttac ttgagtatct gctagtagat tttctttgtt agaatctata
     4201 tacttgtcta ttttttcagt aacactagta ggtattcgat taaagaagta ttctagactt
     4261 tctacgcctc tttgagtaag agcataatat tctctgtcag agtctttata tgtagtcaaa
     4321 aacttagatt ccataagctg agataaaagc tgttgtaatg aaaaataatt catcatctca
     4381 gtctctaata ctacttgagt tatttgagaa ttagttaaat ccattttaat tttttctaat
     4441 atatataaaa ttaaaagttt gtgataggct aattcttcag acgagttttc aaacataaat
     4501 atcatcctcc gtcaaactat ttctatatat aatatattaa actaatttgt acaaaattaa
     4561 aagaacaatt tgtattgtat tattaatctt taataattca tataaaaaca attttataaa
     4621 taaatataga gaaacagggc tgctaattag cagccctgtt gatacccagg tgtcaaaatt
     4681 tactatttat tttccagcca tttgtctttc agccatttca actaatttct tagtcatata
     4741 tccaccaaca tatccatttt ctctagctgt taagttacct ttgtctatgt tttcatagtt
     4801 agataaacct atttcgttag ctatttctaa tttcatttgg tttaaagcag cttttgcttc
     4861 tggaactact gttctgtttg aatttgacat agtaaatttc ctcctcaaat aattagttta
     4921 tgatgtctaa caacactttt atttatgtga tgttaatact aatttctcca aaataaaaat
     4981 aatatataca gaaaaataaa ggtaaaaatg taaaaaatat aaaaaaatta aataaatgag
     5041 tattttagag agtttaatta ggtcaatata ggttttattt ttttagttat tgtcttataa
     5101 attaaatatt acagtacttt tttgagctga aaaaaaataa attttaaata tagaagaaat
     5161 tatttcaaag ggggaatagt atgaaaagag aagttaaaag gactaaagct ttgatatata
     5221 gtgttttatt tttttcatta ttattagtgt taatatttgt ttttgtttat ggaataaaat
     5281 acatatgttc taaatctgac aattcaaaaa tgcctatata taaagttgat acaaatgaga
     5341 aaaaaatagc tttgagtttt gatgtagcat ggggaactga taatatggat gatattttaa
     5401 aaattttaga taaacataat gtaaaagcta ccttcttttt agttggtagt tgggtggatg
     5461 ataatgaaga aattgtaaaa gctatagatg aaaaaggaca tgaaattgga aatcattcaa
     5521 atactcatgc caatttgaag gaaatatcaa aagaagacat aacaaaagag atagaaacta
     5581 catcagaaaa aatatataat ataacaggaa aaaagactaa tttatttaga cctccttttg
     5641 gggacgtaaa caataaagct atggacattt gtagtgattt aggttataaa gtaattaagt
     5701 gggatgtaga ttctatagat tggaaggagc ttggaccaaa tcatgtaatt gaaaaagtaa
     5761 taaaagaatc tcaacctggt tcaatagttt tattccatgc taatataaat gatgtagata
     5821 actatttgga tactataata agtcgactaa aaaaagatgg atacagtcta gtcaaaatat
     5881 ctgatttgtt gtataaagat aattatgtag ttgattccaa tggagtgcaa aaaactaaga
     5941 attaataagt aataaatgta tattttaagt aaagttgtga taaattatat agtatatgtt
     6001 agaaaagtgt cgataaaaag acggtgtcta ttttttgaca ctttttatac atgtatgcaa
     6061 tatcaataat tatagattaa attgattaaa aaagtgtcta ataattgact tttttttgat
     6121 gggtttaaaa atttagaaga attaatgaat gctgtaagac agtatttcca aagggtataa
     6181 gtttgtttaa aagttggcat agaaattgct ttgttaataa gcgatatgtt ctatagaaat
     6241 aaacaatatg ttaagacctt ataatagaaa aatagcatta acattatttg aacagcttat
     6301 aaaaaaatta atatacttaa gggggcgtac tagttgaaca aactatattc tattttatta
     6361 aaacaacacg ttggtggtcc agataagcca gtagtaagtg ttggagatgt agtaaaaaaa
     6421 ggaactctaa tcgcagaacc aactggatta ggggcaaata tttatgccag tgttagtgga
     6481 aaaataagtg aaataaatga ccaagcgata gtaattgaag ctgatgaagt acaagaagat
     6541 acttttgaac cattaaaagg agaaggtata cttgacttaa ttaaagaagc tggagtagta
     6601 ggaatgggtg gagcaggatt ccctactcat gtaaaattaa acatagattt aaatggtgga
     6661 acaatattag caaatgcagc tgaatgtgaa cctttattag ctcataatat aaaagaaata
     6721 gaagaaagac cagaaatagt ttatcaaggt ataaaatatg ctatggaagt tactaatgct
     6781 ggaaaaggta tgctagcaat aaaaagtaag catccaaaag caatagaagc tttcaaaaaa
     6841 gtaataaagc caggagacaa catagaagtt gcagaactag ttgatatgta cccaatggga
     6901 gaagagagag caatagtaag agacgttcta ggaaaattac ttgagccaac tcaattacct
     6961 tcagaggcta atgcagtagt aataaacgta gaaacactaa ctagaatagt agaggctgtt
     7021 gagcaaagaa gaccagttat atctaaaaat ataactgtag ttggtcaatt aaacagtgga
     7081 aaagaatcta tagtgtttga agatgtgcca attggaacaa ctgtcggaga attaattgaa
     7141 agagctggtg gaataaaagg tgaatatggt gaaataatcc taggaggacc tttcactggt
     7201 aaagctacta ctttagatgc tccaataact aaaactagtg gtggtataat agttactatg
     7261 ccatttgtta atgaaaagag aaaaatgggt cttttagttt gtgcatgtgg acctaatgaa
     7321 gaaagaatga gagatatagc aactaaaatg ggagttactg atatagtatc agttcaaaaa
     7381 tgtaaacaag ctcaagaaat taaaggtgca ttaaaatgtg aaaatccagg acactgtcca
     7441 ggacaagctc aaaaatgtat tgaatttaag aaagctggag cagaagttat attaatagga
     7501 aactgtactg actgtagtaa cacagtaatg ggttctgcac caaaattaaa attaggtgta
     7561 tatcatatta ctgaccatgt aatgagaaca gttaatcatc cattaataag aagaataaaa
     7621 ggtgacgtaa gattaaaaat aaaataatag ataaatagaa gttagacatc tttagaagta
     7681 aaacttaaaa gttacttcta aagatgtttt ttaatgtatt ttgagggcaa tatatattgt
     7741 aaaataaatg gaaaaaatag acaaaatatg ctagatattg tataatgata acaatagcta
     7801 ttacaattaa tattggacaa aaataatgat actcaagtat gtggtttgta ttaatatgca
     7861 tattatatta agtcaactat ccgatagagt aaaaggtttt tgtgatattt gaagatactc
     7921 tatagtatct tttttattat aaaaactaat ttttgtcttt tattagataa gtatctagga
     7981 tactaattta tattttattg agttgttaaa aaagtgcact taaaaagtta aaaaagaaaa
     8041 attaaaaaac ctatttatag aaactgtgaa gtatatctta aacctgggca cttaaaagat
     8101 atatggagtt agtagtgcaa cctgctataa atataaatag gagtaacttt taattgtcaa
     8161 aaatatataa aataaataca taaataagta attaatagaa gatagatata aatatatttt
     8221 tgaaatgctc cctgcattca taacgagtgt agagtggcag atatctgccc aaaactcctt
     8281 taattgctgg aagttcctaa agctaactaa accacaacat aatcatgaaa taaggataag
     8341 tgtgatagag tgtgcattta ataagcactt gaggttacga aagtagaaaa aattagttag
     8401 atagcataag gttaaatcct aagtgccttg aaaatggata atcagcaggt aagcttcgaa
     8461 aagaagaaac ttcaacgact agagagaaat ctcgtaccta caagtgtggg gaaatgggga
     8521 gtatctaatt tatggttagg taatgatata gtctgtgctt aatagaaata ttaagaagtt
     8581 cataggagaa ctggttagga gtaacgaccc taattgaaca cactaaagat gtattattga
     8641 ataagattca tataatattt aataatttta attatattaa gtgaatacaa tatatgtttt
     8701 tagtatcagg agaattttga aaacaaaaat taaaaaatca agtataatca gtttagtaat
     8761 tgcttttagt atggtattta ctgcatttac accaatagta tcttatgctg acgaagtgac
     8821 tagcaatgat acaatactta atggagaaga acaatcaaat ggtcagacac cagatgtaga
     8881 gaaaccatca gacggtcagg taccagatgg ggagaaacca tcagacagtc aagtaccaga
     8941 tggggagaaa ccatcagacg gtcaggtacc agatgtagag aaaccatcag atggtcagat
     9001 accagatgta gagaaaccat cagatggtca gataccagat gtagagaaac catcagatgg
     9061 tcagatacca gatggggaga aaccatcaga cggtcagata ccagatgggg agaaaccatc
     9121 agatggtcag ataccagatg gggagaaacc atcagatggt cagatgccag atggagagaa
     9181 gccatcagat agtcagacgc cagatgtaga gaaaccatta gatgagcaaa ctccagaaga
     9241 agaaaaacca ttggaagaag aaatagttat agaggaaatg agtttaaaac aagatattga
     9301 taaaattctt gatatgactt tatctcaaat aaataaaata gtatataact tttgggaaga
     9361 tgaagaagat gtaaaggcag atgaacaatc agaaattaac caagttttta cttcagaaga
     9421 ctcatttatt agcttatggt atgacaaaaa agcaaaggtg aaaaattctt gtttactaaa
     9481 agaaatagat ggttcagata gaccttatca tgatttaaga tttgatgata ttacaaagac
     9541 tttaactttt gactatgtaa taaagggtct tgtaggagca agctcaaaag acgacaaata
     9601 tgtaatagaa ggtgaagatg gagagcaaac tgcattttgt tacaataatc atttaagacc
     9661 accaagtagt aatggaaaga gtccatattt accagcagaa gattttaatg gtcaagaaaa
     9721 ccaaaatgaa gaagcagtta aatctatact atatgcaggt tctgaatttg atggatttgg
     9781 atataagcaa caatttaatt taggcgaaga agaaaatgac ataatgactt actcagctac
     9841 tcaaagtgca atttggatta ttcttggaca aatagatgaa caagaaagac ttaagcagta
     9901 tcaaggctct atagaccttt gtgataaact tatagaaaga gcaaaaactg aagaggaaag
     9961 agctgagtat cagaagagga aagaagtagc gataaataca aaagcttatt tagaagcatt
    10021 gttaaaagca ggtcgtgaag agttaaggcc aaatgataca ggaaaaccta gtttgagtaa
    10081 tggtttaact aagattaact ttgaaaaaaa tgaagatggt acttatgaaa cagaagctgt
    10141 agccttagta ggttatagtg gtgtagtaaa gttaaaacta ccagatggag taactgctta
    10201 tgatgtagat ggtaatataa taggtacagg cgaagtagaa atttcaacgc aacagaaatt
    10261 taaacttaag agtgttggaa aaccagatgc caaagctaat atttctgctg tatcttatga
    10321 ttatattttt ccaaaagcta ttcaatatta taaggcagtg cttgatttag gacaaaaaga
    10381 ccattcatct tcattaccat ctagcaagca aaatttatta agttatacaa tagagaaaaa
    10441 gaatggtcaa gaagttaact ttaatatagg tttaccaaca gatgatgatg atgttgtaaa
    10501 tccaccagtg ccaccaatag atgatgatgt tgtaaatcca ccggtgccac caacagatga
    10561 tacaaatgga cataagccaa aaccatcacc accaatagat gatacagtaa taaatccacc
    10621 agtaccacca atggatgata caataataaa tccaccagta ccaccaacgg aggatgcagt
    10681 gttaaatcca ccagtgccac caacagatga tacagtgtta aatccaccag taccaccagt
    10741 aagtgataca gtggaaaaaa ctccagaact atcaagagat gatacaatag taaaatcacc
    10801 aaaaacaggt gatgaaactc agctaatgtc atatgtattt attagtgtca ttgcaatttg
    10861 tggattagcg tatcaatgta aaataaaaag aaattaatct agattattat taagtttaaa
    10921 ataaaaagtc tcaaattgat ttataagtca ttttggggct tttttatgta aatataatat
    10981 gcaaatatag tttgtttaaa aatatctatt ttaattatat tcttaaattt atgattggat
    11041 acaggcattc attaattgtt tgatgaatag aaaaatgttt tgaaggtgaa aatagtattg
    11101 aaaaaataat atactaaggg tataattcat ttgatttcat ttgtataaat ttaattataa
    11161 attttaaagt gattatataa atttaaatgc taattactta ataaatttta ataataatta
    11221 tttaataaat aattattata atatgctaga ataaatatat ataaataagt tttgatgagg
    11281 tactactata aaggggggac tttatgtttt cgataccaga agtaaaaaaa gtagaagagg
    11341 taatggatac aaaatttaca actatagacg aagacacaag aattgaagat gcaataaaag
    11401 aaatgataaa aagcaacaca aaaactctaa tggtaataga ttcatctgac caattaaaag
    11461 gcattatatc catgacggat atacataatc tttatgagat gcataaaaag tatgaaggtc
    11521 aaccagtaaa acttataatg aagaaggatg taatatatgt caacgaaggt ttaaccttag
    11581 atgaatgtag agatataatg atattaaaaa atatagggat tcttcctgtt cttagagata
    11641 ataaaattat tggagttcta aaacaagagc acattaggga ctatctatat atgcatttag
    11701 aagattatgg attaactttg aagtatatta taggtcaaat taaagaagga atttgtgcta
    11761 taaataacga aggtgttgtt atcttgtgga ataagtttat ggaggaaagg tatgatataa
    11821 agtctgaaga tatagttggt cgaccgatga atgaattttt ggaaaatact atttcagaaa
    11881 aagtactaaa tagtaaagtt ggaatgagtg acttgtattt tacagataaa aaagaaaata
    11941 tgtatgcatt agttcatgca aatcctatat tttataaaga agaatttatc ggtgttgtat
    12001 gtacagaagt tgatgttaca gaagctaaga tattagctct tgaacttgaa aaagtaaatg
    12061 atacattaaa atatctaaag aacgaagtca aaaatttatc taaaggtagt tttgataaga
    12121 ttttaggtaa aagttataaa ttggaaaaat cgaaagcgat tgcaaaacaa gtggctagaa
    12181 caaatagtag catatttatt tggggcgaaa gtggtacagg taaagaagta tttgcaagag
    12241 ctattcatga ttatagtgag agaaaaggtc aatttatacc tgttaactgt agtgccatac
    12301 caaatgagtt atttgaaagt gagttttttg ggtatgaatc aggtgcgttt acaggagcaa
    12361 gtaaaaaggg tcgaataggt atatttgaac ttgcaaaaga tggaactgta tttttagatg
    12421 aaattgccga tttacctctt agtatgcaag caaagttgct tagagtatta caggaaaaag
    12481 aaataagaag agttggtgga gataccacaa taaaaataaa tcctagaata atatcagcta
    12541 ccaataaaga tttgagtaaa atggtaaagg cagaaaaatt tagagaagat ttatactata
    12601 gattaaatgt tgttgaaata aagattcctc cacttagaga gagaaaagaa gacataggat
    12661 tattggttca tagcttttta gaggagatat gtaaacaaaa taataagcct gttcttacaa
    12721 ttagcaaaga tgtaatagat atatttcaga attatagatg gaaaggtaat attagagaat
    12781 taaaaaatac gattgaaaat attgttgtat tgtcacaaaa ttctaaaata gatgtggatg
    12841 atgtaccaag ttatatgatg gattctacaa ataatagtac tgaagaagaa gagtatcctt
    12901 tagatttaac gaaggcaact caaaaaattg aaataaagaa tataaccaag gcacttaaaa
    12961 tgtctaatgg aaataaagct aaagcagcta agatattaaa tatacccaga acaactttgt
    13021 attataagat agaccaatac aaaatagatg tgtctaaaat atgacacatg actaaatttt
    13081 gacaaaatga taaactttaa tttaaaacct agtaaagcca acgcttatat aagtgttgtg
    13141 tatatagatg tgttaaaaaa aatgaaaaag tgttgattaa ttgacacttt ttttgtttga
    13201 gaaaatgttt acaaatacaa aaaataacat attttaaata aatatttata taatatttgg
    13261 ctaaaaatag cgatagatga agaatctatt atagaaaaaa tctttttgtt aataagttgg
    13321 cataggaatt gcttataata taaagtgact ttaagtgaga aaaaaataat attaatcata
    13381 acaaattatg taggttttaa tttacttaat ttctcagtta aggggttacc tgttgaggaa
    13441 ttgagattta aaataataaa taagaaaata atgtaaggag gtattttata ctatgtcaat
    13501 aactttagaa acagctcaag cccatgcaaa tgacccagca gtttgttgtt gtagatttga
    13561 agcgggaaca attatagcgc cagaaaactt agaagatcca gcaatatttg cagacttaga
    13621 ggattctgga ttattaacaa taccagaaaa tggattaact ataggtcaag tactaggagc
    13681 taagttaaaa gaaactttag atgcactttc tccaatgact acagataacg tagaaggata
    13741 caaagcagga gaggctaaag aagaagtagt agaagaaaca gtagaagaag cagctccagt
    13801 atcagaagca gcagtagttc cagtaagcac aggagttgca ggtgaaacag ttaaaataca
    13861 cataggtgaa ggtaagaaca taagcttaga gataccttta tcagtagctg gtcaagcagg
    13921 agttgctgct ccagtagcaa acgttgctgc tccagtggca agtgcagcag cagaagtagc
    13981 tccaaaagtt gaagaaaaga aacttttaag aagcttaact aaaaaacact ttaaaataga
    14041 taaagttgaa tttgctgatg aaactaaaat agaaggaact actttataca tcagaaacgc
    14101 agaagaaata tgtaaagaag ctaatgaaac tcaagagtta gttgtagata tgaagttaga
    14161 aataataact cctgataaat atgaaactta cagtgaagct gtattagata tacaaccaat
    14221 cgctactaaa gaagaaggcg aattaggttc aggtataact agagttatag atggagctgt
    14281 aatggtatta actggtacag atgaagatgg agttcaaata ggtgaatttg gttcttcaga
    14341 aggtgagtta aatactacta taatgtgggg tagaccaggt gctgctgaca aaggtgaaat
    14401 attcatcaaa ggtcaagtaa caataaaagc aggaactaac atggaaagac caggaccttt
    14461 agctgctcac cgtgcatttg actatgtaac tcaagaaata agagaagcat taaagaaagt
    14521 tgacaactct ttagtagttg atgaagaagt aatagagcaa tacagaagag aaggtaaaaa
    14581 gaaagttgtt gttataaaag aaataatggg acaaggtgca atgcatgata acctaatatt
    14641 accagttgag ccagttggta cattaggagc tcaaccaaac gttgacttag gaaacatgcc
    14701 agttgtatta tctccacttg aagtattaga tggtggtatc catgcattaa cttgtatagg
    14761 acctgcatca aaagaaatgt caagacatta ctggagagag ccattagtaa taagagctat
    14821 ggaagacgaa gaaatagatt tagtaggtgt tgtatttgtt ggttctccac aagtaaatgc
    14881 tgagaaattc tatgtatcta agagattagg tatgttagtt gaagctatgg aagttgatgg
    14941 agctgtagta actactgaag gtttcggaaa caaccatata gatttcgcat ctcacataga
    15001 gcaaataggt atgagaggta taccagtagt tggtgtaagt ttctcagctg ttcaaggtgc
    15061 tctagttgtt ggtaataaat acatgactca catggtagac aacaataagt ctaagcaagg
    15121 tatagagaat gaaatattat ctaacaacac tttagctcca gaagatgctg ttagaataat
    15181 ggctatgctt aaaaatgcta tagaaggtgt agaagttaaa gctcctgaaa gaaaatggaa
    15241 tccaaatgtt aaattaaata acatagaagc tatagaaaaa gttacaggag aaaaaatagt
    15301 attagaagag aatgagcaat ctctaccaat gagtaagaag agaagagaaa tatacgaaaa
    15361 agacgaaaac taaaatttag atactaacta agatttagac aataacataa atttagatcc
    15421 aagtttaaaa cagtatagag aggtagaatt ataatggata ggttaaaata tatctcatca
    15481 gagacttttt atgaaggtat tatagttgac atcaaaggcg gtggagtgac tatagaccta
    15541 aaaggtagac ttggacaatt taaaatacct aatagaatgc ttataactga ctacgaactt
    15601 aagataggtc aagaagttgg attcatgcta agctatcctg aggtattaag tccagagcct
    15661 aatcaagagt atgtagaaaa tattaggaga gaaaaagaaa aacaagcaga aatgcaatca
    15721 aaacaagaag aaaaataata aataatcgtt tgaaaataga agggagagga aatatatgag
    15781 ccttacaaca gtacaaggac ttcaatctga aatattcgtt ccaataacac ctcctccagt
    15841 ttggactcct gtaactaaag aattaaaaga tatgactata gctttagcta cagcagctgg
    15901 tgttcattta aaatctgaca agagatttaa tctagcagga gatactacat ttagagctat
    15961 acctaataca gctacagttg atgaaatgat ggtatcacat ggtggatatg acaatggaga
    16021 tgtaaacaaa gatataaact gtatgttccc tatagataga ttacatgaat tagctgcaga
    16081 aggatttatc aaaggagtag ctcctatgca ctatgcattc atgggtggtg gaggaaacca
    16141 acatgtcttc actgaagaaa ctggtcctgc tatcgctgct aaacttaagg aagagggagt
    16201 agacggtgta gttatgacag ctggctgagg tacttgccat agaactgccg tgatcgtgca
    16261 gagagcaata gaggaagctg gaatacctac aataataata gcagctcttc ctccagtagt
    16321 tagacaaaac ggaactccta gagcagttgc tccattagtt ccaatgggtg ctaatgctgg
    16381 tgaaccacat aatatagaaa tgcaaacaca tatattaaga gatacattag agcaattagt
    16441 tgcaatacca tctgctggta agatagttcc attaccatac gaatataaag ctcacgttta
    16501 aaatgtaatt tatatttgaa aatatagaac ccttctccta cacggttagg agaggggttt
    16561 taagaacaaa ggtggatatt atggaagaaa aaataatgag aagacttgtt ataaaaccgt
    16621 ttcatatgaa tgaagttaat ttcggttcaa aaacttctat aaagaaagat gtacttacaa
    16681 tagatttatc aagtatagat gaaataaaag aaagagaaga gttaataaca gacataaaag
    16741 tagacattat aaaacctgga gattatgaca gagaaattaa tactattatg gacattatac
    16801 caatatcaac aaaagtttta ggcagactgg gagagggtat tacacatact ttaacgggtg
    16861 tatatgtaat gttaactggt gcagatgaag atggaaatca aatgcatgaa tttggttctt
    16921 cagaaggaat tttgaaagac caaatggtat ttgggagata tggaactcca tcagttgaag
    16981 attatataat ccatgtagat gtaactttaa agggaggttt accttttgaa agaacacttc
    17041 cacttgcagc attcagagca tgtgatgatt ttatacaaga aataagagcg tctttgaaaa
    17101 tggaagacgg aagaaatgct actcaagttc gtgaatattt tgacaaaatt cgaccaaatg
    17161 caaaaaaggt tgtcatagta aaacaaatag caggtcaagg tgctatgtat gacaatcagt
    17221 tattctcaaa ggaacctagt ggatttgaag gaggaacatc aattatagat atgggaaatg
    17281 tacctatgat tatatctcct aatgaataca gagatggtgc ccttagagct atgacttaag
    17341 agaggtggat attatgggaa taggaccttc aacaaaagaa acatctcttc atcactttag
    17401 agacccactt ttagacatag ttgaaagtga taaggatgta gatttacttg gagtaatagt
    17461 agtaggaact ccagatggaa atgaaaataa aacctttgtg ggacaaagaa cggccgcttg
    17521 gctggaagcc atgagagtag atggagctat agtttcatca gatggttggg gaaactcaca
    17581 tgttgactac gctaacacat ttgaggaaat aggaaaaaga gatatacctg tagttggagt
    17641 tacatttaat gggactcaag ctaagtttgt tgtaagcaat caatatatgg ataccatagt
    17701 tgatatgaac aaatcaaaag aaggtattga gacagaagta gttggagaaa acaacacaaa
    17761 tgaaatagat gctaaaaaag ctttggcatt tttaaaactt aaaatgagaa aacatggata
    17821 aaaaatttaa gtaagggaat gagttttgtg ggaatttcta catcaatgaa aaacacatca
    17881 cttcatatat ttagagaccc gttactagat ttgatagata atgattctga catagacttg
    17941 ttaggagtgg ttgtagttgg gacatcagag cacaatgaat ggaaaacatt tttagcaact
    18001 agacttggaa gatggattga atcattgcga cctgatggag tgattataac tttagatatg
    18061 gcaggaaacc agcacattga ttttacaaat gctatagcag agtttgtaaa atcagatata
    18121 cctacagtag gtcttactat tatgggagca gatggattag taattaccaa tccatatttg
    18181 gataaagcta ccataattga ttataaaaag acaacaggct acatagaaac agaagtagtt
    18241 ggagacaatc acatggatga agttgatgtt aaaaaagcat tggctttcct aaaattaaaa
    18301 atgcgtaaag acgcaaaata aacctaaggg ggaatttgat atgaaattta gcagaagtat
    18361 acaagctata gactctcata cagcaggtga agcaactaga atagttgtag gtggaatacc
    18421 taacataaaa ggaaattcta tgcctgagaa aaaagaatat ttagaggaaa atctagatta
    18481 tttaagaact gctataatgt tagagccaag aggacataat gatatgtttg gttctgtaat
    18541 gactcaacct tgttgcccag atgctgactt tggaataatc ttcatggatg gtggcggata
    18601 ccttaacatg tgtggccatg gtacaatagg agctatgaca gcagctatag aaacaggtgt
    18661 agttccagca gtagagcctg taactcatgt agttatggaa gctccagcag gaataataag
    18721 aggagacgtt acagttgtag atggaaaagc taaagaagta tcattcttaa acgtaccagc
    18781 tttcttatat aaagaaggtg ttgaagttga cttaccaggt gttggaactg ttaaatttga
    18841 catatcattt ggtggaagct tctttgctat aatacatgca agtcaattag gtttaaaaat
    18901 cgaacctcaa aatgctggta aattaactga actagctatg aaacttagag atataataaa
    18961 tgagaaaata gaaatacaac atccaacttt agctcatata aaaactgtag acttagttga
    19021 aatatatgat gagccaactc atccagaagc tacttacaaa aatgtagtta tatttggtca
    19081 aggtcaagtt gacagatctc catgtggaac tggaacaagt gctaaattag ctactttaca
    19141 tgctaaaggt gaattaaaag taggagaaaa attcgtatat gaaagtatat taggaacttt
    19201 attcaaaggt gaaatagttg aagaaactaa agttgcagat ttcaatgctg tagtacctaa
    19261 aataactggt tctgcttata taactggatt taatcatttt gtaatagatg aagaagaccc
    19321 acttaaacat ggatttattc ttaaataagt aataaataaa ttaggaaatt aaaatagaat
    19381 agtagccact tgtcggttgc tattctatag cttttaggct ataagattca gaatatatga
    19441 aaaaataaaa aaataggagg atggattatg gtagcaatct taaaggcatt atatgtagta
    19501 ttcgcagcaa tctttgcagt tgtgtttggt aaagacgtag ctaaagcaaa caaagagggg
    19561 aaactagaag aacaaagtac tccaaaagtt gctgtaacag gatttataac agacttcttt
    19621 gatacattag gaatagggtc atttgctcca acaatagcaa tgtcaaaggc tttaaagtta
    19681 aatataccag ataaaaaaat gcctggtaca ttaaacgtag cacatactat tccagttgtt
    19741 acagaagcat tcatatttac atcaatcata ccagttgatg gtgttacttt agtatctatg
    19801 gttgtggcag cagcagttgg ttcatatata ggtgcaggaa taatagctaa gatggacgag
    19861 agaaaaatac aacttgttat gggtgtaact ttagcattaa cagcaatatt aatgttatta
    19921 ggtcatcctt ggattaacgt attaccaggt ggaggaaatg aattaggtct tactggtgtt
    19981 aaattagtaa taggtgtaat aggtaacttt atactaggag ctttaatgac agctggtata
    20041 ggtctatatg ctccaggtat ggcaatggtt tatttcttag gaatgtctgc aaaagttgca
    20101 ttcccaatag ttatgggttc ttgtgcatta ttaatgccag ttgcaagtat gaaattcata
    20161 aaagaagatg catatactaa aaaagcatca gttataatag ctatatgtgg tttaatagga
    20221 gttttcgtag ctgcatatat agtaaaaact ctaccaatgg atatattaaa agcattagta
    20281 atagtagtta tagcttatac ttctgctaca atgataatgg ctgcaaataa aaacaaaaag
    20341 actgcttagt taaagactac ttagtgttta ttaaatatta cagctaataa taaagattat
    20401 aaactgcttt aaaatattga attaatattt tagggcagtt ttttatttac taaattaata
    20461 taaagcaatt aacatgccaa ttatgtaata tatatagtga tttagtagat ttaatgtaaa
    20521 aaacgttgta tttttaaaga ataaagcata atttaaagct aaatatttaa attttataat
    20581 caataagttc aataaatgtt catatattaa tacagattaa taaaaatata acctgtaata
    20641 agtctaatat aacttataat taagaaaaat aagtttataa tgactcaata ttcatctgaa
    20701 ttatttgaat aaattta
//
LOCUS       DAEQAF010000065        20700 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.067, whole genome shotgun sequence.
ACCESSION   DAEQAF010000065 DAEQAF010000000
VERSION     DAEQAF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.067"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(26..562)
                     /locus_tag="KRN00_002522"
     CDS             complement(26..562)
                     /locus_tag="KRN00_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBH1828381.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFGSDIEEEN"
     gene            complement(580..1893)
                     /locus_tag="KRN00_002523"
     CDS             complement(580..1893)
                     /locus_tag="KRN00_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBH1828382.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            2248..2688
                     /locus_tag="KRN00_002524"
     CDS             2248..2688
                     /locus_tag="KRN00_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBH1828383.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(2873..3061)
                     /locus_tag="KRN00_002525"
     CDS             complement(2873..3061)
                     /locus_tag="KRN00_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1828384.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            4096..4491
                     /locus_tag="KRN00_002526"
     CDS             4096..4491
                     /locus_tag="KRN00_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828385.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNSTCTTE"
     gene            4534..6633
                     /locus_tag="KRN00_002527"
     CDS             4534..6633
                     /locus_tag="KRN00_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBH1828386.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGEAMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIILKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNASTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(6858..12068)
                     /locus_tag="KRN00_002528"
     CDS             complement(6858..12068)
                     /locus_tag="KRN00_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBH1828387.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLNEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNALYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILELSHIYEIFHAVEKIEMQLNREILQKYYSFEKKNKAVLSLDDMNTKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYKWTNRMVNFSDFKLDSDGMKFVLGKQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDVKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNRKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(12083..14578)
                     /locus_tag="KRN00_002529"
     CDS             complement(12083..14578)
                     /locus_tag="KRN00_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1828388.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIES
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMDFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLILIANGGNG
                     SKGIDGKNGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKIEKVVYYRVELSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(15260..15547)
                     /locus_tag="KRN00_002530"
     CDS             complement(15260..15547)
                     /locus_tag="KRN00_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828389.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNVFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(15567..15842)
                     /locus_tag="KRN00_002531"
     CDS             complement(15567..15842)
                     /locus_tag="KRN00_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828390.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(16479..16658)
                     /locus_tag="KRN00_002532"
     CDS             complement(16479..16658)
                     /locus_tag="KRN00_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828391.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(16943..18427)
                     /locus_tag="KRN00_002533"
     CDS             complement(16943..18427)
                     /locus_tag="KRN00_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1828392.1"
                     /translation="MKRKPQYLVIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNLDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFK
                     KLLTYMYKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNI
                     KIGDCLPSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYVTLFSEYDDDYIN
                     TEEGAKRLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVY
                     PDFVLLCKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEIL
                     RYLKKGDVERFAESFSNIFKESLQYLKKVISSLNVDMRVKLDIL"
     gene            19409..20587
                     /locus_tag="KRN00_002534"
     CDS             19409..20587
                     /locus_tag="KRN00_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1828393.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
BASE COUNT         7013 a         3537 c         2254 g         7896 t
ORIGIN      
        1 aatctttttc ttttaataaa tctatttaat tttcttcttc tatatcagag ccaaagggaa
       61 tccatgcatt accaaactct ttatctttaa ataaataagc taatccagtt atttgcttca
      121 atctaagaat ttcatcaact tccataccca ggtgctttga tatccattca tcagattttc
      181 caatttcaca aagttcagtt ataattttac tcattaaatc cacattatga gaacctcttg
      241 cacgattgtg tcgaatagta cttgccattc tttcatcaag agatttatca attactgaaa
      301 caggaagaag tccattttct ctatcatata tatcctcatt ttcaagcatt actctatatc
      361 tatgaaaacc atctacaata atatacttat ccttttcctc attataataa cagacaattg
      421 gcattgtata cccatcttct tttatacttt tatacaacaa ctgcatttct ggtggggcta
      481 ctgcatttgg attatagtcg ttagattcta tcttttcgat tggcactgcg atgattccat
      541 atacaggact tttatattcc atagcatctt aactcctatc taatgaattt tttcatattt
      601 ctttttaata tattccgttc taattctctg ttcttttgta ggaccaaatc ccataaatct
      661 acacatatgg tcatttttta aaatacaata acacattctt ttccaacttg gtatatcttt
      721 ggtaaattta atatcatccg tatcatcagg tatatcatcc aaaaatatga ctctactctt
      781 tttatctttt gtatgatttg aaactccatt taattctatt ttataacctt ttctcaacaa
      841 ttcacgtata actatttctg acaaaccacc acctgtattc tgccaaaact caatagatgt
      901 tgaaaatttt ttaatatagc tattccttat attttcaggt aaggtatcaa gcaaaaaata
      961 tgtgaaactt ttccatgtgt gtccatatgg caatttaaca ctacgatatc ccatagcttt
     1021 tgttttgcca taaatagaag taaaattaac tccttgtact ctagcaacca atttcaccca
     1081 tacatctggg tccaatattc tgtataaatt taaactctct tttgctgaat cattaaaagg
     1141 tgatgccact ctcatttttc ttggagctac tccagcttta tagaataagt cataaatttt
     1201 attatagtca tagtcaaatt tatagtgtgc taaccatata tcttctattt cccaatcata
     1261 tataggagat gccgtccaga catttttaaa ttccttagtt atccagcact ttcctttata
     1321 tccatgctgt ttattcacaa tagaacaata acgttgtaga gattctgctg ctcgtgttcc
     1381 taataagcaa acaacttttg caccttcatg tatatctcta atccatctac caaattgttt
     1441 tgccaaactt tcttgtctca ttttatattt ataataagta aaaggattat ttttttgatt
     1501 tattatgtat tctttgactg gcatttctct tacccataac tcttctttct catcatccca
     1561 tggataccaa tacatttcat aatttcctac agcagttctt gtagccattg gtaaacacac
     1621 ccaatatggt tcaatatctt caatattatc ttcaaatact ttttcaacat attcagtagt
     1681 caaactatat tgagcctcaa aatcttgatg aaatactcct attttggaac ttatattatt
     1741 ctttctctta taatccaaaa ctaaatttag cagtaaacca ctatcttttc ctccgctaaa
     1801 agatacatag atataatcaa attcattaaa aagataagaa agtctttctt gaaaagcttc
     1861 aaatacatcg gattctaaat atctcttatc catttgaatt atcccctttc aattagaagt
     1921 ttataaaacc ttacaatgca atattattat gcttttttag cagtaatcag cataaattat
     1981 acattattta aatacacaaa tccaactaaa tacatataat tataatgtaa ttatactttt
     2041 gtattataaa ctatatttta tcattatttt acattttttt ccaatatata taattatcat
     2101 atttttctat tagctaaaac taattacctt atatttttac gtattggtat aataatacat
     2161 aaaaacttga ataatgcata aaaacttgac atactgttgt cataattact ttgctataat
     2221 taaaagtaaa aatggaggta aattctaatg tatgaacgta tgcttgataa aagcaataaa
     2281 ccctgtttgt ctcaaataat agaatatata ggtaaagatg gatatgcacg attgtgtaag
     2341 ttggaaactt acttgaaaac tcaatataat ttatcaagag aacttcgatt tccttttgga
     2401 aacaattatg gttggggtta caaatatagc cataaatctt ttcatttatt ttatgctttt
     2461 tttgaaaaag gtgcatttac tgttctgatt cagataggtg acaagcaagt tccagcagta
     2521 gaaaaaacgt tggtagcttt gacaccaaaa gctaaagagc tctgggtcac tcgttatcct
     2581 tgtggcaata atggaggctg gattaagtat cgtattttag aagatgcaga cttacttgat
     2641 attattcaat atataagagc aaaaaaatct ccacctaaac aaaattaact tttatttttt
     2701 gtgatttaaa tatagtgtat ataaattcca ttctttccat ataaaaaaaa taatataaaa
     2761 aatatctatt agtataactt atttagtatg tcttattcta ctttttacag ataattaaaa
     2821 agttttatca taaataaatc ataactagac atcctagtaa atcaaaatta atttattctt
     2881 ttttattaga atttttgata atagtcccta tacatatgcc aattatcatt ccaaaaatta
     2941 gaccataaca cattgtgata cctacatttc ctttagaaat acctatagca caacctatag
     3001 ccattccaag tatcatgcct ataaacatac atataataac taaattgttg tttttattca
     3061 tagtttttct ccattcaata tattttaaat tgcctagctc gccttcttag cttaaaacaa
     3121 agaaatataa attaactttc tttcattcta atatctgcct gtataaatgt caaacaacac
     3181 atttcttgtc ataacctcct ctttttgaag taagtataat ctcccagaca caataatatc
     3241 aatttcctaa aaccatttaa gtaactttta tatttacata atatttacaa tcataaacta
     3301 tattgttatt catttataca tcataaacac tccctcctaa tcattattat acttaaaata
     3361 atgttcattt ataataatat atctaacgca ctttaattga aaaaactaaa actttgcctt
     3421 tcattcccat atataaataa gtatactttt tgatgctcta ttacaaatca actaaattaa
     3481 ttgatataaa ttatcatttt ctgttgaaaa taccattcgc acatgctata cttaattgca
     3541 taaatggtaa taaatgtcat atgattttac aaatctatta ataacaatta ttacttttac
     3601 tgtattttaa agtttttgga ctaaatatca agaactttct aaaatacaaa gtacaaaaaa
     3661 tttatataag ttataaattt atatgaacta gataagctca aacaatatgt tatgtataaa
     3721 ctgtgtagta ttcggttata aatttatata aattatataa gctagataaa gtattacctc
     3781 aactatataa gctagatata taaattgctt atataagcta gataagaatt atttcaacta
     3841 tataaactac atatataaat tacatacata agctagatat ataaactaga tatataaact
     3901 gcatatataa gctatataag aattatttca accatataaa ctacatatgt aaaattcatg
     3961 taaatttact aatataaatc aaataaaatt actaaactct ctaaactaat tttgtaaaac
     4021 atactctatt tttaacattt gttaccttat acataagtac aaacaaaatc taactaaatg
     4081 aaaggataat gtaaaatgaa tattttaaaa atgaaaaaaa cagggatatt tttaggagga
     4141 gtactttttg gtactgtagg tgttaagata ctttcaagtg attgtgttaa aaaaacttgc
     4201 actcgtgcaa cagcaggagc attgaaagtt aaagattctg ttcttgaaac aactacgaaa
     4261 attcaagaaa atgtagaaga tattttagct gaagcaaaag aaatcaacga gcaagaagac
     4321 ttatctacat ctaaggtaaa cgttgtacaa gatactctta aatgcgaaca agaagttctt
     4381 aaaactgaaa ctataaaaac tgtagaagat actaattcta atagcattaa atgtgaagaa
     4441 atcaaagata acgtaattga agaaaaaaat agtacttgta caacagaata gatttaatga
     4501 ttattatgat taataatatc aggaggaagt aaattgaatt tttatataaa acacgaaata
     4561 agaggtcgta tacgctttga cttacaactt ggcaaattaa acaacaagca gtccgatact
     4621 ctcttatatt atttaacttc tataaatggt attaccaaag caaaagttta cgatagaact
     4681 ggtgatgcag tcatttatta cactggtgaa agagaataca taataagaga aatcactaaa
     4741 ttcagtttta acaatagcaa aatagaaaac ctagttcctg aacataccag cagggaatta
     4801 aacaattatt atagagacaa attagcaaat aaactgctag tcaaaagtat ctccaaaata
     4861 ttttttccaa agtccttaag atttttttta attggacttc attctataaa atattttaaa
     4921 aaaggtctct cttccctgct aaataaaaaa atagaagttt ctgttttaga tgccactgct
     4981 ataggtattt ctatttttag aaaagatatc aatacggctg gttcagttat gtttcttctt
     5041 ggtatcggtg aactattaga agaatggact agaaaaaaat ctatagacga cttggctcaa
     5101 agtatgtcac taaacattga aaaagtatgg ttaagaaaag gtgacactga aatcctaatt
     5161 ccaatttcag agataaagga aggagattta gtaagtgtaa ctatgggaaa tatgattcca
     5221 ttggatggag ttatagtatc aggagaagca atggtcaatc aggcatcact tacaggtgaa
     5281 tcccttgcag ttaacaaaaa agaaggctct tacatatatg ctggaactgt aatagagcaa
     5341 ggcaatattg ttatgtgcgt caaggaaaaa gctggtacta ctagattcca gaaaatagta
     5401 actatgattg aggaatctga aaaactaaaa tcttctgtag agagtaaatt tgaacatcta
     5461 gcagatacat tagttccata cagcttttta ggaagtatat taacctatgc aattactaga
     5521 aaccctataa aatcactctc tatattaatg gtagatttct cttgtgcatt aaaactctct
     5581 atccctattt cagtactatc agccatgaga gaatgtaaca ataacaacat tactgtaaaa
     5641 ggaggaaaat tccttgaagg tgttgcatgt gcagatacta ttgtatttga taagacaggc
     5701 acattaacaa aagctcaacc aactgtttca gatataatta cattccaaaa ttataataag
     5761 gaggatatgt taagacttgc agcttgctta gaagaacact ttccacactc catagcaaat
     5821 gcagtagttt acgaagctga aaaacaaggg cttagtcaca aagaaatgca tacagaggta
     5881 gaatatatta ttgctcatgg catttcaaca aaagttgatg ataaaaaggt tgtaataggt
     5941 agcaaacatt ttgtatttga agatgagaag tgtactatcc cagacggtga ggaggataag
     6001 tacaacaatc tatcagatga gtattcacac ctatttatgg caatatcagg taaattatca
     6061 gcagttattt gcataaatga ccctttacga aaagaagcaa aatatgtaat ttcaaattta
     6121 agagaatgcg gaataaaaaa gattgtgatg atgactggag atagcgaaaa aacagctaaa
     6181 tctatagcaa gtaaagttgg tgttgatgaa tattattcag aagtcttacc agaagacaaa
     6241 gccaattttg ttaaaagtga aaaactaaaa ggtcgcaaag taattatgat tggtgatgga
     6301 atcaatgatt ctcctgctat ttcagaatca gatgtcggaa ttgcaatgag tgaaggtgct
     6361 gaaatagcaa gagagatttc agatattacc atatcagcag ataatttgaa taatttaatc
     6421 attttaaagc agattagtaa taagcttatg aaaagagttg atttaagttc taagtttatt
     6481 attggcttta atttaggtct gattttactt ggtgtcggtg gatttgttag accaagtaca
     6541 tctgcctttt tacacaacgc atctactgtc ggaataagtt taaacagtat gacaaattta
     6601 ttggaaaaca ccaatactta taactaccat taatctccat tacataaaac atatgatata
     6661 aaaaatttat aattcatctt ttaaaaaaaa tatgtcttaa aattagcttt tttctaatca
     6721 aaattatata aagcatactt tacaaatttt aaactcaact tatttctatt ttttacaaaa
     6781 aaggagatga ttcaaatttt cattttgaaa catccccttt tgtaaatttc tttaaaattt
     6841 atatattaat tatattttca accaataatt gtattttcaa ccaatctttc ttcatagcat
     6901 tttaaatcat tttgctttag ataattaaat tcagactcta cataaatacc acagcctacc
     6961 aattcaattg tcaaattagg tatattttcc tttagtatac tagtctgctc ataaataatt
     7021 ctttccaata aatcaacttg taatatagaa aaatgcttca taatctcccc atcactatct
     7081 atatctttct tgatttcata ccaactcttt gacaaaattc ccttcaaatc aatataccct
     7141 agactcctca atatatctat actatcgctc catgcatact tactaggttt atcaaagtat
     7201 gactctagtt tcttcttctg ctcatttgta agtgaatcat aagaaagctt cctattaaaa
     7261 tgtgccttca aagaaatctt agccatagaa tatggacttc taccagagtt taatcctgca
     7321 tttttgaact tttcaattcc tttatcttct actgaagacc atattgagtt tattgaatct
     7381 gaatcattgt atttaacatc aagaccatgt gtaatattta tatagttttg tggaaataca
     7441 tattgataat agacatcttt tttatcatca tatagagaga agtatccact atcatataaa
     7501 tgaatatgca cctttacttt taaactatcc tctaaaatat ttcgtctaag gttcgggata
     7561 tttgcataca tggttacata ttttatggca tcaaagtttt tatttaatgg aacttcaaaa
     7621 ctaatttcat ctcctgtcaa aagctttttc acttcttctt cattacaatc atatagagaa
     7681 tatgtatttt caaatcccac acgtgatttc ccatctaaac tgcctgttaa tgctaccttc
     7741 aaaatatggt tatctgtttt ttgccattgg taagcatctt ggtcaagaaa ctctctaatc
     7801 tgtctatttt gctctttcgc ctgatttata acctcgtttt catcttctgt aatccctaca
     7861 tggcatctat ttaagatatt tactatattg cttccaaatg ggaatgtcca tagttgaaaa
     7921 gctgctgcct caacctgaca caagtatcta acctgattta attcaatttg atggataagt
     7981 tttttctgat attcattcat ctgattacca ctatctgaca tttgataaat caattctccc
     8041 attgcaagat tatctttttt cttatcaatc ttatcagtaa tgataatttg agtttccatc
     8101 atatcctgta cttttttaaa tattatagaa atctcctctg aattttccat ttttaagctt
     8161 ccaaactttg tgcttaattc agttaaaact tccttcatct ttaatttact tatctcattt
     8221 tcaaaaatat cttgattttt aactgtacta tcgaattttt ctacaaatgg tataacagat
     8281 tctttcaaag ttttatcttt aaattccacc atttgagtat tcaattcatc taatttctta
     8341 atattatttt ctttatcttt aattgcctct ttaactacct ctattttact ctcaaaacta
     8401 gattttacat taagacaatt attaacacca ctaatcgcag tatttataag agaacaagca
     8461 gaacttccaa tactcaatgc atttttaatt ttagatgtct tttgctgtct ttcaatagct
     8521 tgtttacttt tctctagtgc agctaactta tctttttgct gtttattatt gtaatttgcc
     8581 tccaacatac ctatttcttt tttctggatt tttgtgtaaa tttccttata ctcgctttca
     8641 cttaacccct cttttgctct ttgaatatcg tcagctttgt ctgcataatt atcatcatct
     8701 atagacttaa ctataatctc cttaatttgg tcaaatttag ttcttctttc ttcatcaaca
     8761 cctgccaaat tataagtcat tttatctaaa gcattttttc tatcttcact tagctgtttt
     8821 ccaagtacaa atttcatacc atcagaatcc aatttaaaat ctgaaaaatt aaccatcctg
     8881 ttagtccatt tgtattcctc ttctttagct gaaagatttt ccttcaaaga ttttgcactg
     8941 tcaaatgccc ctagacaagc ttgaccaaca ccactaaatg cagtcagtaa actcaatgcg
     9001 ctttgtattc cagaaagaat taactgtgtt ttcatttgtt cctcaagttt tgcctgtttc
     9061 ttttttagtt cctctatgtc ttcttgttca tcttctttca tctttataat ttcttgaatc
     9121 aacaggttca tttttgcatt aacagaaagc attttattct caagttcatt ttttaaaacc
     9181 tctatttgtt gatttccaga ttcaatttga gttaggatac tttccttata tgtattgaaa
     9241 tatccttctt ttaactcatc tttcttccct tgttccaatt ctcttaaggt cttatccaga
     9301 taatctgtca aagaacgaat atctgtaaca cgatttcctc caatttcact ttcttcaatc
     9361 atctgcacat aaaatgctgt cttctgctca agtgcaaata aaatcatact ccattcgcta
     9421 aaattctgat tttttcctac aaaagattct attctatcag actgcatcaa tttatttata
     9481 aggtattcat agatttcctt tgcttcttta taaaattctt tctttgtatt catatcatcc
     9541 agagaaagta ctgctttatt tttcttctca aaactatagt acttctgaag tatttctcta
     9601 tttaattgca tctctatttt ctcaactgca tgaaaaattt cataaatatg tgaaagttct
     9661 aaaatatcag cttctaaaat tcctactgca cacaacagtc taagatttct ataaccttta
     9721 attccagaaa aaccaaatct ctcgaaaaat tcatagaaga atgtatctat tgacaaagaa
     9781 tactcctgct ttaacaattc cttttctttt agtgcatctc cagagtgacc ggcttttccc
     9841 tctgctccgg ctgaacctga atcttcacgt ttgctaattg tccagtcctt atgttcttca
     9901 taaagagcat ttaatttctc tccatcatct gctgcttgct tctgatttaa agcatgatta
     9961 aacacatatc tatcaaaata atagtagttt ctatcactat tatccattgg aggagaggta
    10021 cctatatatc ttattgtttc ttcatatata cctctaattc caccaagacc tcctgcacca
    10081 ccagctcctc cagagcctcc ttttcctgct aaaccatgat ttccatcttt tttacttata
    10141 gcacttttta ataaaggagc ttttccaagg agataaacct gtccagactt gcttccaaga
    10201 cctgcatttc caccattacc tcctgtgcct ccagttccac cttgttttcc tttttctgct
    10261 tttaccacat agtattttgt acctttaaca ttagcaaatt cttttgactc ttttttagaa
    10321 cctattttag catttgcccc agcttctcca gttatccctg tatctccttt ttttccatct
    10381 tgtccatttc caccacgtcc accatctacg taaagtttaa gttctcctct tttttcgatt
    10441 tctttaaaag ataatatgat atcacctgaa gtacctgcat tatttccatt tcttccattc
    10501 attccgtcgt aaatagaact ttctccaacc aatttttctg catccttacc agatacgttg
    10561 attgaataag tcccttctgg tatatgtaat ttttctgtaa gtagtacaat attcttacct
    10621 gagaagactt ctttctccat attacagtca attttcaact cacaatctcc atacatatat
    10681 atagatgaca aaatattaag ttgataacca gatattattt tagtcaaatc cgataaattc
    10741 actttaggta taggaatata tatagaaagt acattttctt tctcatatga ttttatatat
    10801 gtacaacttt gaatcttctc tatcctatac tctgcatctt caagcttttt ggcttcttct
    10861 tccctatatt cttcttctgc tatccaatat ttgatatctt ttaatgtatc ttctaaagta
    10921 ttttttagca atgattttaa caactcactt agaccaacaa tatgagtctc actacagtaa
    10981 ctatttaact ctaaaagaag gcgtgtttct tctaatatat tcactttctg tacgccatca
    11041 ccatatgaaa gttcttgtac aaactccata agctctttca tattattagt cctactacat
    11101 aaatctgtat acatcttatc taattgaatc tttttatctt ttagactatt tatagaagat
    11161 agaatggaaa tagaatcttc catacctttt ttaacacttt ctatataagg aactaaaagt
    11221 ttttctaggt ctttataggt tacatcaaca gctttttgta tttctatttt acaagaagca
    11281 gtaagcatca atcccaaatc tgttttttca aatgtttcag gtagattttt catttcattc
    11341 aacaactttt ctggctgttt atctagtgga ttacataatt taatagatac accatctgat
    11401 aatgctacat ttaataagta cactaattcc ttacaaccgt cgtaatcttt ctcttgacta
    11461 tctaggtctt cttttgcttt ttccaatata tttcttattt tttcttctgt tacattacca
    11521 attagtgttt taggtatttt attgataaga aagaagaaat tttctttata ctttgcataa
    11581 tcaccaagca tatctttcaa atttttgcct gtttctatca ataatgtatg tctagagtcc
    11641 agtagggatt gatagtctaa aataactacc atccctttta cctttgaaga tgtggaaata
    11701 gtttccctta caagcatagc accagcaatc atatactctg ctccacggtt gtcaaaaaaa
    11761 cctgggcaat cacataatga aaaatctcta tttgcaatat ctacaacttc tggacataaa
    11821 gtcttagaat atacaccatt tccaatttcg acagctgaat cttttgcagt tatatatatt
    11881 tgtccagtct cttcatccgt tttttcttcc atcacacagc cttttaaata atttatacaa
    11941 gtactctttc caacgcctga agcacctagg aataacaaaa ttgacttttc ttttaagtca
    12001 tattttctaa gctcgtctct tccttcttcc aaaaggttta cgatttcact ataaagttta
    12061 tttgccatac atccatccct ttctatattt cggaacaata gccttgatat ttttctttaa
    12121 taagattctc ttctaccttt gaaacagctg ttgataactt agtgtttgga gcattaaatc
    12181 ctccattgtc tcctctatct ccatattcag cgtattctct tgctggtcct gttttacctt
    12241 cattccagct tccaccacta agttccacac gataataaac tactttttct atcttataat
    12301 cccaacttgt aaaatatcct gtatagtata cagtcttatc tataccactt ggagaaaatg
    12361 aaagtgtatt atatccgtga tatccaccac ttcctccata tccacctaaa cctggtctac
    12421 catttggacc tgcttctcca tctttcactg ttatatcaca atgattaatt attctatttt
    12481 tttgttcctc tgaatctgaa atgaagtaaa tattaccttt cttaccagca tttccacctc
    12541 ttccagcatt tccaccagct ccaccttttt cacctttttt gccacttgta cctttttcaa
    12601 aatacccttt aaacatctgt ccgtggaaat aacttgtata tcctgcatca gctccattac
    12661 ttccagaagc tcctgtttca ccatttttcc catctattcc tttagaacca tttcctccat
    12721 ttgcaatcag tattagacga taatttctaa tttcttcttt aatatataag taaatattac
    12781 ctgcatctct accatcttca ccatttttcc catacataga attatctaca agttctccgc
    12841 tctttccact tacattaatt tttacattac tacctacatc aagattgtta gaagcaagaa
    12901 taatattttt ctctgatgca aagtccattc caaggttatc atccatataa atagtatctt
    12961 tagcaaagaa cataaatgta gaaacattgt catctacttt tctatttttg aaatattcca
    13021 atacactgct aattactaag tttggaatta atgctcttat ttcaatacct ttcttatcat
    13081 taatattaat tgtttttact ataaatggat ttaaaatgta tttaccaata aattctctaa
    13141 ttatctcatt accttcttct ccatatgcac ttaatcttgt tatactgtct tctaactctt
    13201 cattttgtgt aactgtaaca tttgtcaaaa ttgaattaaa atcacttaca ctatatacat
    13261 aatccttttt atttgcaact tccattaatt tttctctatt tggtaatgta aatacctgtt
    13321 tttgcacttc ataagaaact aaaacttttt ctaaattctt tcttattata atgaagtttt
    13381 gttccattat cttcttactt gccttttcta taataaattc catatgtaca gaaggtaata
    13441 aaatttcccc agttccatgt tctgtatatt tacttaaagc atcaattata tctaagtttc
    13501 cttttatctt attttgtaat ttcatgcaac tatcttgtaa gaataagcca ctttgtttgg
    13561 ctaatacgtt gataaaactc tctatagtaa gacttgttgt actttccaac cagtttttaa
    13621 atacttttac aacctcatca tattttgcta tttcttgaat cattgttata cttccaataa
    13681 tattgataaa atcttctgta tacgccttaa cataatcttc taggctagat acgatattgt
    13741 tttgaatttc ttttatcaac gtatctaaaa ctaatcttgc atctgcacta attggatatt
    13801 ggaatgctga tgtcttatct ttaacttcat ctaattctag tacttgcttt aataagcctt
    13861 ccctctcatc tgatgcaagt ggcttacaaa gatgaatatt ttttccatta tcttttagca
    13921 attcttcaaa taaccaagct ttttcctcta tattactgtc taaattttcg cataattgtt
    13981 catattttct ttttataaca ttatatattt gtttttctgt tcttcctaag aaactttttg
    14041 aaatgaaaaa agttatacta cccttaaaat tttctttatg aagacacata tttaactgtt
    14101 ggaacaggtc tagtactttt gtaagtctag aatctaatat atctgcttct ggtatcaata
    14161 caattactgc acatatagat gcagaatttt taaatacttc acctaatgaa actgctgcac
    14221 taatatcatg ggctactccc ctattgtcgc taaaacctgc agtatcacat aattttgcat
    14281 ccattccttc tattggtttt ctcatattta caatgttcgg gtataaagtt tgagaaacag
    14341 ctcctgaacc aatctctgcc acagggtcta agcaatcaat atatgatata ccagtatctt
    14401 catcttctac ttccatcatt acacatcctg caagatagtt aattgcagta cttttgccac
    14461 atcctgtccc accaagaatt agaattaaat tttgattttc agccttattt attgctactt
    14521 ttccttcatt taataagagt gttatttctt ctaaaagttg attgttattt tctggcattt
    14581 attttccccc ttggttatat attttattta aataaagttt aatcccttaa gtagattaca
    14641 aagtttttag actatattta aatttgtttt ttatttttta tttttaataa atttgctttt
    14701 tcactcaatt tgctttttca ctcaataatt attcttcttt gtttattaaa ataactgtgt
    14761 tgtataatat aatctttacc aacacagtta ttttatttaa tgcgcttatt ttattgtatt
    14821 ttatgtaata cagttgtttt ttatattata tgtccattat tttcccatgg ttattacata
    14881 tagattttta attatatttg taccattaat ttaaacattc ctatactact gcttaagttt
    14941 tacacctata ccagcttgaa tattttattt ttatttgctt aaatagttca actatactgg
    15001 ttaaataggt tatctttatt tgcttaaata gttcaactat actggtttaa ataggttatc
    15061 tttatttgct taaatagttc aactatactg gtttaaatag gttatcttta tttgcttaaa
    15121 taagttcaac tatactggtt taaataggtt atctttattt gcttaaataa gttcaactat
    15181 attggtttaa ataggtttcc tttagtttaa atagttcacc tatacctact tgaatagttc
    15241 acttttattt gcttaaattc tataccaata ctggcttaaa cattatacta ccatgattgt
    15301 attgtctatc ttcaactaca ataaaaacag gttctaaatc tttagtagat gttattttta
    15361 attctaaaaa aacattatca gttggtaata tttttacatc ataattattt aaattattat
    15421 tcgtgatact attaaataca tcaccttgac gttcaaaaaa aacattatca actattacaa
    15481 aataaacatc ttcttttcta ctattttcaa cctctatagt attttgttta gttacattta
    15541 gtctcatctt ccacctccta ttaatattac ttaattatat taatacttgt aattgttgca
    15601 ttatgttcat cacaaggaag aggtttaaaa acaactatct ctgctaaata attctgtgga
    15661 ggatttgtaa ctgaagtagc attgcaaata aatttaaaat ttgttcctgc tacaacttga
    15721 gtagaaacaa taagtggttc ataaccaacc ccttctaaca ttcctacagc ttcattaaat
    15781 acttttaaat cttcttcttc gacagctctg aattttgacc atccaccaac aaaaagactc
    15841 atataaaaac ctcctttata tatatattta tttatatata tagtagtacc aattttctca
    15901 atattcaata ttttctgtgt aactggtcaa tgaaaatgca taactggata aaaatactta
    15961 taaaataact taactttaca tataaatagc ttactttaca tgtaataaga ttattctaca
    16021 atatgaaatg catcttgttt tgaatatatt ctaaatacaa taatggatat tttcaattat
    16081 tataattaga aaatatccat tacttaactt gttttattta aaatcacata gagactttat
    16141 tatttttttt attgcatgaa tagctatttc aggtatcata aggtgatata ccccctcctt
    16201 gaaaccacaa aaaacatgac aaactttacg aatcttgtct taaaaaacca caggtacatt
    16261 ccttatttgt ggattggagt agccatcaca agcaaatttt acaattttta tgatgacaaa
    16321 aatcaataaa atcgcttagt atataacacg aaatactact tgttactatt aagaatagtt
    16381 agataggaag tatgcattat accaataaag gaatcaataa agaaagttaa aacatcccta
    16441 caaattaaaa atctgttaca tttttctata tttaaacgtt atttacttac aattggagaa
    16501 ataacaggtt ttccttctcg gtcaagtaaa ggcgtaaatc cggctgcatt gccataatag
    16561 tgaaatacat agttcacacc tgtttcttta tccacccaaa tctccgttgc atttattttt
    16621 ccttgtgaat atactttttc aaatctatct tttcccattt tataatcccc catatttttg
    16681 attggtctat accttcttca cttaagtcga aaaaatacat aacttatttt tttaattcta
    16741 atatgagcac gtaaaaatgt caaacagctt atttaatttc ataacttcat gttactgtta
    16801 gtaaccttgt ttgtttactt acactacatt acagcaccat tttatccttt acattattgt
    16861 attgcacaca gtaaaaatgc ttactttatg ggatttttca actaaaaaaa ggattttttc
    16921 tccacagaac atttactatt ttttataata tatctaattt tactctcata tcaacattta
    16981 atgaagatat aacctttttc aaatattgta aagactcctt aaaaatatta gaaaaagatt
    17041 ctgcaaatct ctcaacatct ccttttttta aatacctaag tatctcaaaa catacatcaa
    17101 aacgtgtttt caaaatttca ttatattctt catgaaaaaa tctctctaaa tagattccaa
    17161 atatcatata ttgttttaaa tgcaaaaatg tttcctgtaa tacataaatt tgtgtataat
    17221 ctactatctt acaaagtaaa acaaaatctg gataaacctt acactcttca caattatttt
    17281 gtaagtacct taaatgagtt tctattttat ctacagctat caaatccatt ttatttccta
    17341 gtaaaagtac tacatcctca agagtaatcg taacaaactc catagcatcc aaaagcaaac
    17401 tcaacctttt agctccttct tctgtattta tataatcatc atcatattca gaaaaaagtg
    17461 ttacatatgt tcccttgcca ttaattgttt tagcaattcc caattcattt agctcattat
    17521 aggcacttct aactgttgga agagatacat tatatctatt aattatcgaa gtaattgatg
    17581 gtagacaatc tcctatttta atattgcctt caaaaatttg acaaattaca tctgaaacaa
    17641 ttaagtcata taaataacat ttttccaacg ttacagaatt aaaactactt gtatctatac
    17701 tttgtggagc acgattttct accattttaa gtatggattc tctacaagct ttatacatat
    17761 atgttaatag ttttttaaat tcaattagat tcccgtccaa tccatataag taagtttttc
    17821 ttacctgctc tatgtattta ttacgaaaaa agtctataca acaattatcc aagttatcca
    17881 agttatccaa gttatcgaaa ttataggcca attgtgaaat aatgacatca tgctgaataa
    17941 tctcacaaaa atggtgaatc aggaaattat ttgttttact tattagttta tttatatatt
    18001 ttagcctttg ttctttaaag actaaataat tagaactatt tttttccata caatcgataa
    18061 tctcgtttaa ttcttcaaag tctttagatg taaatctttt aatattgtac atagcaatag
    18121 aaggaaatat taaactaaaa atcttatata tttctgatat ttgtaaaatc ttctcatata
    18181 ataagtcaga ttctattgat tgtttactcg tactctggat taaaactggt ctagaaccag
    18241 cttttgtctc tataaagccc ttttctgaga gcatttttat tacagttttt atagtatttt
    18301 ttgataccat atattcttct gacatgcttt ttatagaatc aagcctatct ccaatagtaa
    18361 ttttaccagt ataaatttgt tgaattatat gctcaaaaat aactaaatat tgtggttttc
    18421 tcttcatatt tttcctcttc gataaattag atttattgtt ttttgtaagg tatatttact
    18481 tttatttaat agggcaaaat agttgcttat tttttcctca taatctataa ttaatataaa
    18541 ccatttatat atatggtcta agttttataa tactgtaatg cagtaaaata gcatattgta
    18601 gctatactac agcaaattaa cataccattg tagtatatta attggaataa ttttaagtac
    18661 ttcaaaattc catcaaaaca tatatgtgtt tttgatatta tgtatattcg ttaatagaat
    18721 agctatactt gttttacata ataaattata tgatacttgc tatatgtaat tactatattt
    18781 aatacacata actattatac ttactatatg taattactat atttgataca cataattatg
    18841 atacttacta tatataatta ctatacttgg acacataact attatacttg ctatatgtaa
    18901 ttactatact ttatacacat agttgttata catgctatat ataattacta cacttggaca
    18961 cataactact atatttacta tatgtaatta tactatactt ggacatatag ttatcataca
    19021 tactatatgt aattactata cttggacaca ttattatatt tgctatatgt aattatacta
    19081 tacttggaca tatagttatc atacatacta tatataatta ctatacttgg acacattatc
    19141 atacatacta tatgtaatta ctatacttat acacatagtt atcatatata ctatatataa
    19201 ttactatact tggacacata gttatcatac atactgtata ttaagatata atacttttta
    19261 aattttatat aacacagaca catgcaataa aaaagaaggt atccataata agctctttgc
    19321 atgtacctaa ataaaaactg taaaatagaa tatataaaat ctaatctatt ttaagtaaat
    19381 acaatttcac tttaaaagag gatgtactat gaaataccat atatttttaa tcataactac
    19441 tatattaata atcgaactat gtaacattta catatgcaaa atagcatctt ttggaaacaa
    19501 aaatataact atacataaga attacaaata tattttttta ataaaaccat taaccttctt
    19561 gataataata ttcacaaaat taccattacc actatattat atattgtttt acatagtaag
    19621 tcataaattg ctcttaagca gaaaaagttc tactaacaac cattttattc ccaatatggc
    19681 agtaataagt ttttgtattt tacaccttat tactgtaagt acaatatcac ttgttaaaaa
    19741 tacaagtcca gatataatat ttgcaaatat gacctataag ttaattagta ttttaatagc
    19801 ttctatttta gattttatct tatggtactc tatgaataaa ataaaagagc atatttatat
    19861 aataactcaa aatcaaatag agttcagtct atttttaaaa tttatctggt tcactttagg
    19921 atatatatta tttgatagta tacaaattac atttgctcca ccaagttctc taacttccta
    19981 ctttatattg ggaagtaaca tattattaat cttacaacta attatattca tcaatcatat
    20041 atattccatt gaaaaaaata tttatttaga aaaagaacat aatagactaa aaatgataaa
    20101 acaagaacaa ttactaaaag taaatttatt aaagaaaaaa gctaacattg atgaattaac
    20161 atcagcatat aatcgaaaat ttgcttttga aaaaatacag cattacattg ataacaattt
    20221 attattttca ttgatatata tcgatttgga taaattaaag acgataaatg atacatatgg
    20281 acatttagct ggggataact atattattaa cttctcaagt atagttattg aaaacttagg
    20341 aatagatgac atatttgcta gaataggagg agatgagttt atagttatta tgcctaaatc
    20401 taatgaaaac accacaaaag aatttataga gaaaataagt aaaattatgg ataatacgat
    20461 atcttttagc tatggtattg tagaagtttc tagcgaaaac aaaatgactg tagaagaaat
    20521 tattaatatt gctgatatta gaatgtacac taataaacaa aataatcata aaaggaacaa
    20581 taactaaaat gaatatttac atgagcttac ttgtagtctc actatgtttt ttatcttatt
    20641 atctctatca ttataatttt tttaaatatc tggacataat gattaataac tctaaaaata
//
LOCUS       DAEQAF010000066        20664 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.068, whole genome shotgun sequence.
ACCESSION   DAEQAF010000066 DAEQAF010000000
VERSION     DAEQAF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.068"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            214..1536
                     /locus_tag="KRN00_002535"
     CDS             214..1536
                     /locus_tag="KRN00_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH1828394.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            1833..3194
                     /locus_tag="KRN00_002536"
     CDS             1833..3194
                     /locus_tag="KRN00_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH1828395.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            3267..4661
                     /locus_tag="KRN00_002537"
     CDS             3267..4661
                     /locus_tag="KRN00_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1828396.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            4723..5193
                     /locus_tag="KRN00_002538"
     CDS             4723..5193
                     /locus_tag="KRN00_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBH1828397.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            5196..7412
                     /locus_tag="KRN00_002539"
     CDS             5196..7412
                     /locus_tag="KRN00_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1828398.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSIDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKMFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGCVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            7495..8166
                     /locus_tag="KRN00_002540"
     CDS             7495..8166
                     /locus_tag="KRN00_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1828399.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            8529..9743
                     /gene="dpaL"
                     /locus_tag="KRN00_002541"
     CDS             8529..9743
                     /gene="dpaL"
                     /locus_tag="KRN00_002541"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH1828400.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            9870..11057
                     /locus_tag="KRN00_002542"
     CDS             9870..11057
                     /locus_tag="KRN00_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBH1828401.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFIGTEGYYGILKSV
                     YGK"
     gene            11190..12560
                     /gene="hydA"
                     /locus_tag="KRN00_002543"
     CDS             11190..12560
                     /gene="hydA"
                     /locus_tag="KRN00_002543"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH1828402.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKIAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            12578..13984
                     /locus_tag="KRN00_002544"
     CDS             12578..13984
                     /locus_tag="KRN00_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1828403.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            14056..14502
                     /locus_tag="KRN00_002545"
     CDS             14056..14502
                     /locus_tag="KRN00_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH1828404.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVEGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            14541..15335
                     /locus_tag="KRN00_002546"
     CDS             14541..15335
                     /locus_tag="KRN00_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1828405.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLENELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            15325..17616
                     /locus_tag="KRN00_002547"
     CDS             15325..17616
                     /locus_tag="KRN00_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1828406.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGSDKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            17617..18930
                     /locus_tag="KRN00_002548"
     CDS             17617..18930
                     /locus_tag="KRN00_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1828407.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            18966..20051
                     /locus_tag="KRN00_002549"
     CDS             18966..20051
                     /locus_tag="KRN00_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBH1828408.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASVGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            20281..>20664
                     /locus_tag="KRN00_002550"
     CDS             20281..>20664
                     /locus_tag="KRN00_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828409.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEMTVMKEDMSEVKQEMIVMKEDMSEVKQEMIVMKEDMSEVRQEINIMKEDISEVRQ
                     EMTVMKEDMSEVKQEINVLKEDMSEV"
BASE COUNT         7959 a         2312 c         4236 g         6157 t
ORIGIN      
        1 aataaatgct ttaataaatt atcaaatact aacaaatata ataaaaatta tatatgtaaa
       61 acaattatgt taaaaaattg gcattataat tgcttcatat taagttgaga tgacaaaata
      121 aaaaaagaaa ggatgttgtg tgagataata ataactgtca ttaaaaaata gttgggagtg
      181 ataaccttga gtaaatatca aaagaatgtt tctatgtttg atattgatgg aaggccacca
      241 attttaaagt gtttgccact atcaatgcaa catatactag caatgatagt tggaactgtt
      301 acagtaccta tagtcgtagg aggagctgtg ggtgttagcc ctacacaaat aacactttta
      361 gtgcaatatg cattaataat agctggtata tcaacactta tacaactata tccaatagga
      421 aatattggtt caagattgcc tataattttt ggagttggtt ttacttatgt accaacactt
      481 gtagcagtcg gaggaaatta tggattagca agcattttgg gtgcacaatt aataggggga
      541 gtggctacag tattaatagg gatattcata aaaaagataa gaaaattttt tccgaatata
      601 gttgcaggaa cagtggtttt tacaattgga ttatctttgt atcctatagc aataaattat
      661 atggcaggtg gtgtaaatag tcctacttat gcctctatgc aaaactgggc agtagcggct
      721 ataacattag tggtagttat aggtcttagt caatttgcaa aaggatatgc aaaattggca
      781 gcaatatttt tgggaattat agttggatat tgtgtatctt tagttctggg tataataaat
      841 tttgacccta ttagagaggc aacttggttt gcgataccta aaccgcttga atttgggatg
      901 gaatttgata tgcctgtaat aatctcagta gtaattgtaa gtataatcaa tgctgttcaa
      961 gcaattggag atttatcagc tactacaatg ggaggcatgg ataggaatat cacagataag
     1021 gaattatcaa gtggagtaat aggaagtgga atttgtacta tgataggagc tttgtttgga
     1081 ggtttaccac catcatcata tagccaaaac gtggggatgg tagctatgaa caaagtaata
     1141 agtagatttg tgcttggaat agctggtata tttatgttat tgtcggggtt tgtgcctaaa
     1201 tttggtgcat taatgactac tataccatat tctgttttag gaggagctac aatatctata
     1261 tttagtatga taacaatgac aggtataaag ttaattatta cagaagagtt gtcatcaaga
     1321 aatattacca ttgttggttt ggcaattgcc ttaggcatgg gaataacatc agtaccagca
     1381 gcccaagagg catttccttc atttgtaaag ttagtatttg gagaatctcc aatagtaatt
     1441 gcaacattgg ttgcattcgt tttaaatcta ataataccaa ataaaagtct agaggatgag
     1501 gctaaagaaa gagctgttat ggaagagact aattaagata taataattta aaagaattgt
     1561 ttaaattatt tagtatgaga ttgttagatt atttttgata gctattcatt ttaataaaaa
     1621 atttaacaaa taaatatata ccaggcaatt aatgttcatt taagttgaaa atcggggagg
     1681 gaatatttag aaatttgtta attttttata aaaatagctc agtttagctg tgtttatcgg
     1741 ttgagcaata aattcatggt cataaaaata tttatagaaa ataattataa aaatatttag
     1801 tcaagatatt tatgtatggg aggatttatt ttatgaaaac acgtaatact tcaaaatatg
     1861 atgtcgatgg gataccacca ctaaaggaat caataccttt ggccttacaa catctgttag
     1921 caatgatagt aggaaatatg gtacctgcga tattaatagc aaacgtggta ggacttaacc
     1981 aggggcaagc aacaatgttg attcagggtt ctatgttagc agcaggttta gcaacgtttt
     2041 tacagttata tccaatacct ttatttaaag gatttaagtt aggttcaaga ttacctgtaa
     2101 tgatgggaat gagttatgta tttttaggag cttgtctttc agtagcagct aaagatggtt
     2161 tagcagctct atttggagca cagattgctg ctggggtaat cgtattcttt gtaggatttg
     2221 gagttaagaa aattagacat atattcactc caatagtttc tggaactata atagcatgta
     2281 tgggacttgg actattcgca acagctataa agaatttagc tggaggagaa ggcacacaaa
     2341 catttggaag cccaataaac ttcacagtag gagttatagt tgcttttgta ataataatga
     2401 taaataaata cggtaaaggt ttagtaaaaa attcttcaat attaatagga atattagtag
     2461 gttatgctat atctttagtt ttaggattgg ttgatttctc agccgttcaa ggagcagcta
     2521 tagtatcttt accaacacca gcagcttttg gattagaatt tagaccagag ttaatagtaa
     2581 tgtttactat tatttacata ataggtatag ctgatatgat gggtgcctgt acaatagcta
     2641 cagtaggagc aatggataga gaggtaactg acgaagaatt agcatcagtt gttttaggaa
     2701 attctataac ttctataatt tcatcactat ttgcagctct tccaactgga gtatttagcc
     2761 aaaatacagt aattgtatct atgaacaaag ttacaagtag atttgtaata gcactagggg
     2821 cacttgtatt attactagca gggatatctc cagcattggg tgcaataatg acaactatac
     2881 catcttgtgt tgttggtgga gcaactttag tagttttctc atcaatagca atgtctggtt
     2941 tctctattat gagtatggat ggattcactg aagaaaacaa tcttatagca ggtgtatcta
     3001 tagcaacaag tatgggtctt acaactgctc cacaagtttt agaccaattc ccagaaacaa
     3061 ttggaactgt ccttggaggg tcaagtatag tttctggagc aataatagct atattacttc
     3121 aaacattatt taaattaaag tcacgtaaaa gtgctgaaaa cgttacttca aatcttgagg
     3181 aaaatattgg ataaatgtat tagatataat atgagaaaac catatggtaa aatgttgtaa
     3241 tgaaagtatt caaaggggga tttaagatga ttgatatact aataaaaaat gcaataattg
     3301 ttacagttaa taaagacaga gatgttatat ttgatggagc aatagctatt caaggtgaca
     3361 gaatcttgga cataggaaat acagttgata ttgagcctaa gtatcttgat gctaaaaaag
     3421 ttatagatgc taatggaaaa gtaatattcc ctggctttat aaatactcat aatcacctgt
     3481 tccaagtgtt attaaaaggt ttaggtgatg atatggcact tcatgagtgg ttaaatacaa
     3541 tgatgtttcc atcagcaaaa ttcttaacag aacaagatac ttatgatgct gcaatgcttg
     3601 gatgtatgga aggtttaaaa agtggtataa ctacaatggt tgattatatg catactcaca
     3661 atagaccagg acttacagat ggaatagtaa aggcatataa agatttaggt ataagagggg
     3721 ttgtaggtag aggttgtata gatttaggta ttcacaaaga gcttatagaa gatgtggaaa
     3781 cggttgaaaa agatttgaga agggtattcg aaaaatatca taattcagaa aatggaagaa
     3841 taaaaatctg tgtagctcct tcttcaatgt gggctatatc tgaagaaatg ggtaagatgc
     3901 tttggaatat agttaaagaa tatgattcat attttacagt tcatatatct gaaacagaat
     3961 ttgcaagaac agcaacaaag gatatacatg gagaaataga tataaaatta cttgaaaaat
     4021 ggggtatagt aggtccagaa gttgtagcag tacattgtgt atgtataact gatgaagaca
     4081 tggaaatgct taaaaagtat gacataaaag tttctcataa tgtagcaagt aacatgtatc
     4141 ttgcttctgg tgttgcacct gtgccagaaa tgttaaaaaa aggtataaat gtgagtttag
     4201 gtcttgacgg tgcagcaagt aataacgcac aagatatggt agagcttatg aaattaacag
     4261 ctttacaaca caaagtaaat aattgtgacc ctctggcaat ttctgcagag aaagttcttg
     4321 aaatggctac aattgaggga gcaagaactc ttagaatgga agatgaaata ggttctttgg
     4381 agattgggaa aaaagctgac ctagtaatat ttaactcaat gctttctcca aaatcaatac
     4441 ctcttcacaa tcctgtatca actttggtat actcagctag tatgcacaat gtagagagtg
     4501 ttttagttga tggaaatgta atacttgaaa atggaaaagt aactacaatt gaaagtgaag
     4561 aacaagtgtt gcttaatgca caacatgcag cagaagaatt atgtaagaga gctaatgtaa
     4621 ctaatagaat ggaaggacat aagtggaata gcttatacta atattaaaat aagattgtaa
     4681 taatattcta ttacaacatt agtttatctg taggaggaga aaatggaaaa aataaaatta
     4741 aatattaatg attacatgta tgaaatagaa gttgaaaaga atgaaactct tttgcatgta
     4801 cttcgtgaaa aattaaatct aactggagcg aaacaaggtt gtaatagtgg cagttgtgga
     4861 gcatgtaaag ttttgataga tggagttgac atgaaatctt gtaaacttct tgcaaaaaac
     4921 tgcgaaggta aagttatata cactatagaa agttttgcta atggagaaaa tcttcatcca
     4981 atacaagaag cttttataga agttggagct gtacaatgtg gatattgtac tcctggtatg
     5041 attataacaa cacaagctct tttaaataga aatgcatctc ctaatgaaga tgaaattaga
     5101 gaagctttta aagaaaatct ctgtagatgc acaggatatg taaagattat agaagctgta
     5161 aaattatctg cagctagatt agggggtaga taattatgga aaaggtaata ggaaaatcat
     5221 accctctaaa agatgcagct ttaaaagtta ctggtcaaat gaaatacgtg gctgatatga
     5281 aaccacaaaa tgtactttac gctaagatgc ttttaagtcc tgtagcacat gcaaaaataa
     5341 aaagtataga tacaagtgaa gctgagaaag tagtaggtgt tagagctata gctacttatc
     5401 tcaatacatc acaaagaaaa tacaatggtt cattaagatt ttatgagcac aaaatacctg
     5461 aaaatgaagt tatattttca gatacagtta gatttgttgg tgaccgtgtt gcagcagtag
     5521 ctgcagagac tccagaaata gcagagaaag ctgtaaaact tataaaagtt gaatatgaag
     5581 aattgccagc tgtatttact atacaagatg caataaaaga agatgctatc tgcatacatg
     5641 gagattcaaa tatagtttct caaaacaaca taaatggggg agatgtagaa aaaggcttca
     5701 aggaatgtga ctatatattt gaagatgaat actctactcc agcaatacat catagtgcaa
     5761 tagagactca tagtgtaatt gcacactatg attataatga taaattaact gtacatacac
     5821 cttgccaaaa tacatttgga tttagaataa tactatctca aatttttggg atgtcattaa
     5881 ataaagtaag agttataaga cctgctattg gaggctcatt tggtggaaaa ttagaactta
     5941 caattgaacc agtagcagcc gcattatcaa aaatgacaag aagaccagtt aaaatggttc
     6001 ttacaagaaa agaatctatg atatcgacaa gaactcgtca tgggtctttt gtaaaattaa
     6061 aaactggtgt aaataaagat ggtgaagtaa tagcacaaga cataaaaata tatacaaata
     6121 caggagcata tgcatcaagt gctttaaatg ttataggagc acttagtcat aaagtattta
     6181 aagtttataa aataccaaat ataaagttta ctgggatgcc tgtatataca aatacaccaa
     6241 tagcaggagc tatgagaggc tatgggtcac ctcaaatatt tatggctcaa caagctcaat
     6301 ttgcgaaaat agcaaaggaa ataggtatgg atttagtcga ttttcaaaat aaaaatgcag
     6361 tagagccaga tgatgtcgat ataatcttcc acggttctct tggaaatcct agagtattgg
     6421 attgtataga gcaaggtaag aagatgttta agtgggatga aaagaaaaaa cttccaaaag
     6481 aagaaggaaa atatttaaga ggtataggta tggcaatagg tgcacatggt aatggagttt
     6541 ttggtgcaca tagagatgtt gttacattga ctcttaaatt aaatgaagat ggtacgttga
     6601 cactactaac aggagctcat gatatgggta atggtgttgt aactatgcaa acaatgatgg
     6661 tagctgaagt tttaggaata acacctgata aagttgatac atttgaaact gatacggatg
     6721 catgtacatt caaccttggt gactatgcaa gtagaggggt atttgtagaa ggtggaggag
     6781 ctaaaaagac agcagagaaa ttgaaaaatc ttatattaga agaagcagaa aaattacttg
     6841 aaacatcaaa agaagattta tatctagaca atggatgtgt aattagtaaa cttgatgaaa
     6901 atgtaaaagc atcactttct gatgtcgcag tatatagtca aagtaaatca ttaagagagt
     6961 taactgttgt tgaagattat tcttcaccag ctggacgtac ttcttatggt gtacattttg
     7021 ctgaagtttt agtagataaa gaaactaagg atataaaagt agttgatttt gtagctgtac
     7081 atgatgttgg tagagttata aatcctctaa atttagaagg acaattagaa ggtgggattc
     7141 atatgggtct aggatacgca ttgagtgaag aattggcatt tgatgaacaa ggtagaccta
     7201 aagctactga ttttaaaaca tataaattat ttagaactgt agatatgcca aaatgtcaag
     7261 ttgcatttgt agatggttat gaaaaagctg ggccttttgg tggtaagagt attggagaat
     7321 gtgccgttgt accagttgcg ccagctgttg caaatgcagt atataatgca actgatgtag
     7381 agatacattc attaccaata aaattaaaat agtataaatt aaagcagaaa taacaattta
     7441 ttgtatttgt aaatagataa taaaaataga tttatttggt gaggagatat tattatggca
     7501 aagatattag gtatttgtgg aagtccacgt aaaggagcaa cagaatatgc agtgttagaa
     7561 gctttgaaag aagcagaaac tatacctggt atagaaactg agtattggtc agttagaggg
     7621 aaaaaaataa gtccttgtgt acattgtgat gcatgtataa gaaaagaaac tatgtgtatt
     7681 ataaaagatg atatccaaga attagagcaa aaaatattgg aggcagatgg aattatagta
     7741 ggttctccag tttatgatat gaatataact gctcaactta cagcagtatt taatagactt
     7801 cgtccaatgt atttagttca tccaggaaaa cttcaaaata aggttggtgc agctataact
     7861 actggtggaa ctagatatgg tggccaagaa ttgacaaaac ttcctataat aaatttcttc
     7921 ctaatgcatg aaatgttagt gtctggaggt ttaggtggat gctatatagg tggtacaata
     7981 tggagtaaag atggaaaagc aaaaggtgcc caagaggatg agacaggtat ggacacagta
     8041 aaaagacttg gaaaaggtgc agcagaggca gttatggttt ctaagtttgg tcttgaaaaa
     8101 tggaatgtcg taaaagaaga attagatgtt aaaaaagatg aaaaatcacc tcttagagac
     8161 cactaaagat ttattatatt attgaatata tacaaatagt gatgtaatag attattgcat
     8221 cactatttta tgttttaatt tagattttat agattttata ttaaaaaata tagaaacaaa
     8281 gtgttttgag atttattttt aaattttaaa aatgagaatt aaaaagtgag aagatagaaa
     8341 aggtttttta gttattaaat tctacataca ttgtatgaac taaagataga aaagaaaaaa
     8401 taataaaagc attgcaattt ctatactaaa gagtcataga aaaatatcta gtatatattt
     8461 agtgttggca tgttaattgc ttatatatta aagtataaaa atttaacaat aatttggagg
     8521 tattttagat gttaaaagaa attaaatgga aagtaaataa tttgccaaag ggcgataagg
     8581 aaaattgtat caaattttta aatgaagaag aaataactaa ggttagaaat tttcacaaaa
     8641 gctttcctca atataaagaa actccattag caaacctaga aggtttagca aaaaaattag
     8701 gtgttgcagg agtatatgta aaagatgaat cttatagatt tggattaaat gcatttaaag
     8761 tattaggtgg ttcttattct atgggtagat acttagctca aagattagat acagatatat
     8821 ctgagttagg gtatgacaaa ttaacttcaa aagaaataaa agaaaaatta ggagaaataa
     8881 ctttctttac agctacagat ggaaatcacg gtagaggagt tgcttggaca gctaataaat
     8941 taggtcaaaa atctgttgta ttaatgccaa aaggttcttc tgaatttaga ttaaataaaa
     9001 ttaaaggaga aggtgcagat gctagtataa cagacttaaa ttatgatgat gcagtaagat
     9061 tagctaatga ttatgcagaa gctgatgacc atggagtaat ggttcaagat acagcatggg
     9121 acggatatga agaaatacca gcatggataa tgcaaggata tggaactatg gctcaagaag
     9181 ctatagagca attaaaagaa tatggagtag atagaccaac acacgtattt gttcaagcag
     9241 gagttggttc acttgctggt gcagttcaag ggtatgttgc ttcaatatat gatgaatgcc
     9301 caataacagt agtagtagag gctgatgaag ctgattgtta ctataaatca gcagaagctg
     9361 gagatggaaa accaagattt gttggaggag atatgccaac tataatggca gggcttgctt
     9421 gtggagaacc aaatactata ggatttgaag tattaaaaaa tcatgcagca gcatttgttt
     9481 cagcaccaga ctgggtttct gctaaaggta tgagaacatt aggtaatcct ttaaatggtg
     9541 atgaaaaggt aatttctgga gaatctggag cagttacaac tggtctttta gtagcagcta
     9601 tggaaagaga agatttagca gatttaagaa aagatttaaa attagatgaa aattcaagaa
     9661 tacttttaat aagcacagaa ggagatactg accctgacaa atatagaagt atagtttggg
     9721 atggagaata tccaagtata taaggaatta ctaaaatgca attattagat attggtttac
     9781 atatttagaa gatatataag ttctaaaatt tagaaaatat ataagtatat aaaatacata
     9841 cattataaaa aatttagggg gataatgaaa tgttaaacga acaaagaaaa caagaagtaa
     9901 ctgaaatatg ccaaaaatta attcaaaatc ctagttcttc tggaaatgaa gaaggtgttg
     9961 taaaagcaat agaagagtct tttgaaaaat taggttttga tagttggtca agagatagat
    10021 atggaaatat agtaggatgt ataaaaggta acaagccagg taagaaaata ttatttgatg
    10081 gacatataga tacagttcca gttccagatg caagtaaatg gagtgttcct ccttttgaag
    10141 gaaaaatagt tgatggaaag atatatggta gaggaacttc tgacatgaaa ggtcaatata
    10201 ctgcaatgat gtctgctgta gcgtattttg ctaaagacac taatagagat tttgctggag
    10261 aactatatgt agcaggtgtt gttcatgaag aaatatttga aggtgtttcg gctagagaga
    10321 taagtaaggc tgttcaacct gactatgttg taataggtga gtcttcagag ttaaacttaa
    10381 agattggtca gagaggtaga ggagaaatag tagtagaaac ttttggtaaa ccagctcact
    10441 ctgctaatcc agaaaaaggt gtaaatgcag tttataaaat ggctaatgta atccaaaaga
    10501 tacaacaatt agtacctcca actcatccag ttttaggtga tggaatatta gttttaacag
    10561 atataaaatc ttctccatat ccaggagcat cagtagtgcc agattattgc aaagctactt
    10621 ttgatagaag attattagtt ggagaaacaa gagaaggcgt attagctcca atacaagctt
    10681 tattagatga aatgatgaaa gaagacccag aattaaatgc aaaagtttct tatgcggttg
    10741 aaaaagctga ttgctataca ggaaatacta tagaaagtga aagattcttc ccaggttggt
    10801 tatatgacga agaagatgaa tttgttcaag cagcatataa gggattaaaa gaagctggaa
    10861 tagattcaga aataactcaa tactcattct gtacgaatgg aagtcactat gcaggtgaag
    10921 ctggaataaa aactatagga tttggtcctt ctaaggaaaa tcttgctcac acaatagatg
    10981 agtatataga gcaagaacag ttatttatag gaacagaagg ttactatgga atattaaaat
    11041 ctgtatacgg aaaataatat ttagttcaca ataaattatt taaatatagt ctagaggtgc
    11101 tgaatatagc acctttagaa aatacaattt taaataaagt tttacaatac ttagaaaata
    11161 ctttaaagct taaaagttag gaggtatata tgggaacaat actaagaggt ggaactataa
    11221 ttacctctga taagacttat ataagtgatt taaggataga agatgaaaag atagttgaaa
    11281 taggaaataa cttagaaata aatggtgata aggttattga tgctacaggt aaaattgtaa
    11341 ttcctggtgg aatagacaca catactcatt ttgatatgaa tgcaggttct attacaactg
    11401 cagataattt tgaaacagga acaagagcag ctatagctgg aggaactact acaatactag
    11461 attttgcaga agccaatgag ggggaaaatc tactgcaagg tgtagaagca tatcataaaa
    11521 aagcaagtgg aaattgttat tgtgattatg gttttcatat gacaattaca tgtttaaata
    11581 aagatacatt taatcatatg gaaaaactta tttcagatgg gatagtatct tttaagatgt
    11641 atatggcata tgatggcatg aaagtagatg atggaacaat atacagggtt ttaaagaaag
    11701 caagggattt aggttgtata gttggatttc attgtgaaaa tggggattta ctagatgtat
    11761 tgatagaaga aaatatacaa aatggtaatt tggagccaaa atatcatcca cttacaagac
    11821 ctaacatagt tgagaaagag tctgtttcaa gacttgctga tataactaaa ttatctaatt
    11881 caaaatccta tgtagtccac ttaagttgta gggagtcact tgaaactgta aaaatagcta
    11941 gagaaaaaaa tatagatatg atagtagaaa catgcccaca gtatctatta ttagaagaca
    12001 atttatataa taaggataaa tttgagggtg ctaagtatgt aatgtctcct cctttaagaa
    12061 aaaaagaaga cataaattac ctttgggaag gattgtctag tggagatatt caaacagttg
    12121 gcacagacca ctgttcattt aattttaagg ggcaaaaaga cttgggaatt gatgatttca
    12181 gtaagattcc aaatggagca cctggtgttg aacataggtt agcactttta tatacatatg
    12241 gggtcttaga aaatagaata agtgtaaata agtttgtgga agttacttct acgaatgctg
    12301 caaaaatatt tggaatgtat cctaaaaaag gtgagatagc tgtaggaagt gatgcagata
    12361 tagtcatttt aaatatcaat aaagaagaaa caattagtta taaaactcaa aaacaaaatg
    12421 tagattatac tccatatgaa ggatttaagg ttaaatgtaa agttgaagat gtatttttga
    12481 gaggaaatca tgtagtacaa agttgtaatg ttaaagaaca tccaacaggt caatatatta
    12541 aaagaaaaat tactaaataa tgcgggggga aataagaatg atggatatac ttattaagaa
    12601 tgccataata gtaactgtga ataaagagag agaagttatt tttgatgggg cattagtagt
    12661 aaaagataac aagattgctg atattggaaa ttctaaagag atagaaagta aatatactga
    12721 tgttaaaaaa attatagatg ctaaaggtaa agttttattc ccaggtttta taaatacaca
    12781 taatcattta ttccaaacct tattaaaagg attgggagat gatatggtac ttaaagactg
    12841 gttagaaact atgacatttc cagcagctaa ctatttagag ccaaaagata cttatgatgc
    12901 tgcaatgctt ggatgtattg aaggacttag aagtggtata acaacaatgg ttgactacat
    12961 gtatcctcat agtaagccag gtctttgtga tggaataata gatgcttata aagaattagg
    13021 aataagagga atacttggaa gaggatgtat gaatacagga gctcaatttg gagttcatcc
    13081 tggaataatg caagatgtag aaacggttga aaaagatgta agaagattgt ttgaaaaaca
    13141 ccataataca gaaaatggaa gaatcaaaat aggagtagct cctgcagcaa tatggtcaaa
    13201 ttctcaagaa atgcttgaaa tgctatggag agtagtaaaa gaatatgatg atgctttatt
    13261 tacagtacat atatcagaga ctccttttga tagagaagca gcaaaagaat tgcatgggca
    13321 atatgacata gatgttttag aaaaattagg aatacttgga ccaaatgtgc ttatggtaca
    13381 ttgtgtgtat ctaactgaaa aagatatgga acttactaaa aaatacgata tgaaagtgtc
    13441 tcataataca gcaagtaata tgtacttatc ttcaggtgtt gcaccagtgc cagaaatgct
    13501 taaaaaagga ataacagtta gtttaggagt agatggagcc gctagtaata actctcaaga
    13561 tatgcttgaa cttatgaaat taacagcact tcaacataaa gttaataagt gtgacccatt
    13621 agcaatgtca gcagaaaaag ttcttgagtt ggcaactata gatggagcaa gagctattgg
    13681 aatggaagat gagataggtt cattggagat aggtaaaaaa gcagacttat taatatttaa
    13741 tccaatgctt tcaccaaaag cgatacctat gcataatccg gtatctacat tagtatattc
    13801 ttctagtatg aaaaatatag agagtgttat agtagatgga aatataataa tggaagattc
    13861 aaaaatattg acagctaatg aagagaaagc attaaaagat gctcaagata cagctgagag
    13921 actttgtgta agaggaacta taaaaaatag aatggaaggt cataaatgga atagccttta
    13981 ttaataaatg taatttattc ataaaaaagt atagtaaaac tttagcttaa aaatatgagt
    14041 tttgaggtga tttatttgat tatcaaatgt accataaata ataaagaaaa agaattaagt
    14101 ataagaccag atgatttttt agcagataca ttaagagaaa atggatatgt aagtgttaaa
    14161 aaagggtgtg atacaggctc atgtgggtta tgtacagtga tggtaaatga caaggccgtg
    14221 ctttcatgta attatcttac tgctagagta gaaggtcagc atattacaac acttgagggt
    14281 gtcttggatg aagcaaagaa gtttggagat tttcttgcag acgaaggggc tgaccagtgt
    14341 ggattttgtg ctcctggatt tataatgatg gtcttggcaa tgaaaagaga gcttcaaaat
    14401 ccaacagaag aagaagttat agattatgta aatggtaacc tttgtagatg tacaggatat
    14461 aaaggtcaat taagagcaat acataaatat ttaaacactt agacttttaa gtgaaaatta
    14521 agttgatatg gggagagagt atgataacta taaaggaata tgtagttcca aaaagtttag
    14581 atgaagctta tgaactgcta atatcaagaa aaaacaacat aatacttgga ggatgtggat
    14641 ttttaaaact aggtagtaaa aatattggtt cagcaataga tttaaaagac ttagctttag
    14701 attatataaa tgaaactgat gatagcatat taattggagc agatacaagt ttaagaactt
    14761 tagaattaaa taaggttatt aaaaattact gtaatggggt aatttcaaac gctgtttcta
    14821 atatagtagg agttcaattt agaagtggag ctagagtagg agctagcgta tttgctaagt
    14881 atggattttc agatttaata ccttcattac tagtggtaga tgcaaaggtt aagttatata
    14941 aaaaaggggt tatgaactta gctgattttt tagaaaatga gcttgaaaaa gatatattaa
    15001 tagaagttat attacctaaa aaagatgcta taggtgtatt tgattctata agaaaatgta
    15061 caggtgattt tgcagtatta aatggagcaa tgttaaaaga aggaagtatt tataaaattg
    15121 cgataggcgc tagaccaaga agagcaaaaa ttgcctataa agcaagtgaa atattaagtt
    15181 tagaaaatga tatagaaaaa gctggtgaag tatcaagtga agaactttca tttggaagta
    15241 atataagagg aagtaaagaa tacagaaaag atatggcaaa agccttagta gtgagaatgt
    15301 ataatagtat tggaggtgag tgtgatggta aataaagagg taagaaaaat agatagtgaa
    15361 gccattgtta ctggaaaacc aatatataca gaagatttaa tttttcataa agatgtttta
    15421 acaattaagc ttcttagaag tccacatgct tttgcgaaga taaaaaacat agatataaaa
    15481 aatgcattaa aggtaaaagg tgtagtaaac atattcactt acaaagatgt tccaaattat
    15541 agatattcaa tggttggaga gtcatatcca gaagcatcac ctcatgacca attaatactt
    15601 gaagacgtag ttagatatgt aggagatgaa gttgctataa tagccgctga agatgaaagg
    15661 gctgctatta aagctatgaa acttataaaa gttgaatatg aagtaatgac tcctatattg
    15721 gatgcaagag aatcggaagg aaataaaatt ttaatccatg aagaagatga tttgttttgt
    15781 ccatttgatt ttggattgga tgctacaaaa aatattgtat cgagagaaaa aatgggtaaa
    15841 ggggatgtag aaaaagagtt taaagaaagt gatgtaatag tagaacattc ttatatgact
    15901 caatcacaag cccattgtat gatggaaact catagagctt atacgtatat agatacgaat
    15961 ggcagattag tagtaacttc tgcaaaccaa tcagcttatc atatgagaag acaggtttct
    16021 aaagcactgg gaatacctct ttcaaaagtg agagtaataa aaccaagaat aggtggaggt
    16081 tttggtggaa aaaacatagc tgtaacagag atatatgcat catttgtaac ttggatgaca
    16141 aaaagaccag caaaactaat ttatactaga gaagaaactt ttgcaatgac taatactaga
    16201 catcagatgt tttttgatat aaaaattggg tcagataaag aaggaaacat aaaagctata
    16261 gatatgaaag cattgaacaa tacaggcgct tatggcgata atggaccttc agtttgctct
    16321 gaatcaggtc ataatgtact tccaacatat aataatgtac ctgcaataaa atttgatggg
    16381 agaactgtat atactaattt agttccagga ggagcattaa gaggatatgg agcaacacaa
    16441 ggtacatttg cacttgattg tgcaattgat gaattagcgc ataaacttaa tatggaccca
    16501 acagaaataa agttaaagaa tattataaaa aaacaaactg aaggcggaat aatgaatttt
    16561 ccaataagaa gttgtgcact tgatgaatgt ataattagag gtaaaaaact tattggatgg
    16621 gatgaaaagt accctgttag ggatattgga aacaataagg tgagggctgt tggaatgtct
    16681 gtgggaactc atggttctgg tatagccaac atagacatgg caatagtaaa tatgaggatg
    16741 gatgaagatg gaacttataa gttgttttct gggtcttcag acttaggaac tggttctgac
    16801 acaatacttg cacaaatagc tgcaaaagca ttgaatacat ctattgatag aatttccgtt
    16861 tatacaggag atacagatat gtgtccatat gatactggtg catacgcttc ttgtactact
    16921 tatgtaactg gaaatgctac aataaaatct gctgaaagtt taaaacaaaa gatattaaaa
    16981 gtagcacaga agaaactcga tttaccaata gatgatttaa tactatatga agacagagtt
    17041 tgttatagtg aagatgtaga gaagtttgtt ttgttaagtg aattaggaaa agaatctgtt
    17101 ggtggtggaa atcaagaagt tttatattca tctgaatctt atggtataca agagagtgct
    17161 aaaccattct tagcaggatt tgctgaaata gagttagata aaacaacagg ggagtttaaa
    17221 gtaataaatt atgcttgttc tacagattgt ggtacagtta tgaatcctgc acttgctaga
    17281 atacaagttg aaggtggtgt aactcaaggt atagggcttg caatgtatga agaccctaga
    17341 catggttctg atggaaagct tcaaacttct aatctattac aatacaaagt tccaacaaaa
    17401 aaagatatag gaaacataat tgttgatttt gtagataatt atgagccaac aggtccatat
    17461 ggagctaaat ctttaggaga gatagttatt catacacctg caccagcaat agcaaatgca
    17521 atatacaatg ccacaggagt tcgtataaga gaacttccta taacttctga gaaagtttat
    17581 atggccatga aaaaattaaa tcagggaggt aaataaatga ttgctattaa aagtaaatac
    17641 ttaatatctt ctgctgatga aatatataca aattctgctg ttgtagtaga aaatgacatt
    17701 ataaaagata tattgccaaa tgaagaagtt gaaataaaat ataaaaatat tgaagaaata
    17761 atagataaat cagatgctat aataatgcca ggattcgtca atggtcatat gcatcaatat
    17821 ggagttcttt ctaggggaat accggcaaat gtacatttta ctgactttga aggtttttta
    17881 aatgactatt ggtggccatt tatagaaaat agaattggat taaaagaagt gaaggcaaca
    17941 actaaagcat cagcaataga acttatagaa tctggtgtgg tagctttttg tgatacccta
    18001 gaagctccaa atacagaaga aggaacttta attgagcaag gaaaaatact agaagaaata
    18061 ggcatgaaag cgattttatc cttagaaagt tgtgaaagaa taagctttga aaatggactt
    18121 agatgtttag atgaaaattc taatttaata aagtggagta gagaaaatag taaattaata
    18181 aatggaataa tgtgtacaca tacaagcttc acatgttctg atagatttat taagaaagct
    18241 aaagaagatg caaaaaaatt aaatgcacca atgcaatttc atttatgtga gagtatatat
    18301 gagccaaact atgctgaaaa acactttggc aaaaaagcag ttgactacta taatgattta
    18361 gatatattgg atgaaactgt attagcatct cagtgtgtaa aagtaaatga tgaagaaata
    18421 gatatattaa aagaaaaagg cgtaaaagtg gttcatatgc ctcttagtaa ctgtgaagta
    18481 ggtggaggtt tttctccagt accaaaaatg attaaaaaag gcataaaagt ggcactgggt
    18541 actgatggat atataaatga tttttttgaa gttatgagag gtgcattttt aatgcataaa
    18601 tcagttgaag aagatgcatc agtaatgcca gcaaatttag tatttagaat ggcaacagag
    18661 catggtgctt atgtattagg acttcaaaat tctggtaaaa tagcagttgg taataaggct
    18721 gatataatag ttatggaaga tgaatttaaa actcctgtga ctcttgataa tatatttgac
    18781 cagatagtag ttcagggtaa aaaagaattt atatcaaatg tatacataga tggtagacat
    18841 attttaaaag aaaaacagtt agttgattta gataaaaaag ctattgttaa agaaatgaaa
    18901 gaagttgctt gtgaattttg gaaattttaa cgaatgtaaa tatatatgaa aaggggaagc
    18961 agataatgta taatttttta ggtaaagaat taaaatcacc acttataata ggttcaggac
    19021 cattaacata tagtgcagct ggatgcaaga tattaagtga tgcaggagca ggggcagttg
    19081 tgactaagac tataagaaaa gaaagagcta taaatccagc accacatatg gttagaaata
    19141 cagctaatgc tcttttaaat aatgaaaaat ggacagattt tgagccagag caatggatag
    19201 attttgaaat accacaaatg aaaagagatg ggactgtctg tatagcttca gtaggtcata
    19261 caattgaaga aagtagcgaa ttagtagaga aagttgcaaa tgcaggagct gactttattg
    19321 aattagtatc ttatgactat agagatttga taccaatgct taaagatgca aaggaaagag
    19381 taaatatacc tgtaatagtt aaacttcctc ctatgataga tgagataggc gattttgcta
    19441 aaaaattaga agaagcagga gcagatgcaa taactgcttg tgattctgta ggaccagcat
    19501 ttagaataga catagaaaca gggcaacctt tattaggtgg aaatggaata ggatatttaa
    19561 gtggagaaac tatcaagcca ataactttac agagaatata tgaaataaaa aaacaagtta
    19621 atataccaat aattggctta ggtggatgtg taagtggaga tgatgcctta gaaatgatta
    19681 tggcaggtgc tgactttgtt ggtatatgtt cagtagtaat tttaaaaggc gcacaagtaa
    19741 tatctaaaat acatgatgat ttaaaatcta atcttaatag attaggatat aatactatag
    19801 aaaatgcttg tggtatagta cataatcata tgggagatgt taatgaaaga cttagctttg
    19861 agtttactta tgatgaagaa aaatgtacta aatgtaagat gtgcgagaga gtttgtgcat
    19921 atcaagcgag aaaattgaat gataagatgg aattgaatga agaagagtgt agatattgtg
    19981 gactttgtat atcagtttgt aaaccaaaag cacttggaag aaaaatttca tgttcagagc
    20041 tgaatgtata gattatttta taaaaaacaa agttttaaat aaaaataaga aaggctatct
    20101 caaagagata agcctttttt gttgttgacc ttatttttgt ttatttgtag ttattttaga
    20161 tattaattag ttttgaagta ataaagtgaa tcaattttgt ttaattaaaa ttttaataat
    20221 tctgatatat atgttaacat tgtatagcat ttgtgtaaaa tgttataata attaataggg
    20281 atggtgatgc aagtgcaaga gaagatttta gagttattat atactataaa tgaagatgta
    20341 gttagcataa aaaatgatat gtcggaagta aaacaagaaa taaatgtgtt aaaagaagat
    20401 atgtcggaag taaaacaaga aatgactgta atgaaagaag atatgtcgga agtaaaacaa
    20461 gaaatgattg taatgaaaga agatatgtcg gaagtaaaac aagaaatgat tgtaatgaaa
    20521 gaagatatgt cagaggtaag acaagagata aatataatga aagaggatat atccgaagta
    20581 agacaagaaa tgactgtaat gaaagaagat atgtcggaag taaaacagga gataaatgta
    20641 ttaaaagaag atatgtcgga agta
//
LOCUS       DAEQAF010000067        20606 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.069, whole genome shotgun sequence.
ACCESSION   DAEQAF010000067 DAEQAF010000000
VERSION     DAEQAF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20606
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.069"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            523..1416
                     /locus_tag="KRN00_002551"
     CDS             523..1416
                     /locus_tag="KRN00_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBH1828410.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1416..2810
                     /gene="gltA"
                     /locus_tag="KRN00_002552"
     CDS             1416..2810
                     /gene="gltA"
                     /locus_tag="KRN00_002552"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBH1828411.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIIF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3176..5395
                     /locus_tag="KRN00_002553"
     CDS             3176..5395
                     /locus_tag="KRN00_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1828412.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNIKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5542..6288
                     /locus_tag="KRN00_002554"
     CDS             5542..6288
                     /locus_tag="KRN00_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828413.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIILPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6288..8168
                     /locus_tag="KRN00_002555"
     CDS             6288..8168
                     /locus_tag="KRN00_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828414.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8287..9678
                     /locus_tag="KRN00_002556"
     CDS             8287..9678
                     /locus_tag="KRN00_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1828415.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9785..10825
                     /locus_tag="KRN00_002557"
     CDS             9785..10825
                     /locus_tag="KRN00_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1828416.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11314..11967
                     /locus_tag="KRN00_002558"
     CDS             11314..11967
                     /locus_tag="KRN00_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1828417.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSSGGHIPWVLK
                     PVMNKGLNYVESIMKFIGIKKFDELLVDGTGTSEEERQAAIEKASEKIDGIIDGMKF"
     gene            12043..12252
                     /locus_tag="KRN00_002559"
     CDS             12043..12252
                     /locus_tag="KRN00_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828418.1"
                     /translation="MREEKSNEKYDCYWCNQENNFCVEIKDNIVMIDDGTGTLKQAVF
                     IGYKQIQINLNCSHCQNLNRIKLNL"
     gene            complement(12392..12958)
                     /locus_tag="KRN00_002560"
     CDS             complement(12392..12958)
                     /locus_tag="KRN00_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBH1828419.1"
                     /translation="MMNNELNTIILETLNNADITSNDIPSIDLYMDQIISLIDNKLSA
                     NKRFESDKILTKTMINNYSKEGLIKPVKGKKYTKEQILQMIIIYSMKNTLTIQEIKRI
                     LHGVYEKDNFSEKDLVSCYEKFMLIKENQRKNIPDFIESNFENISINPENKDDLLIAL
                     LSLTSMADQLKNISEKLVDRYFPDIIKK"
     gene            13119..13772
                     /locus_tag="KRN00_002561"
     CDS             13119..13772
                     /locus_tag="KRN00_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBH1828420.1"
                     /translation="MYQFFLKGRDPISSLTHFIGACLSLLATIILVFQSVTLQETSLL
                     MIVSVSVFGLSLIALYSASSYYHFLKGTPEQELFFRKVDHAMIYVLIAGSYTPICLNF
                     MEKKEGIIFVTAIWIVAFIGIIIKIFWMDAPRWLSTSIYLLMGWAIVFDINAFNSIPK
                     DCLRLLIMEGVSYSIGAIIYIIKKPNISPEFGFHEIFHIFIMIGSLFHFLAVLLYVL"
     gene            complement(13930..14106)
                     /locus_tag="KRN00_002562"
     CDS             complement(13930..14106)
                     /locus_tag="KRN00_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828421.1"
                     /translation="MYKYDDYVNLTNDLDLPVEIRNKCVRIVSVSENLEDIIIVHKFK
                     LYVVNEKYIKGIME"
     gene            14634..15578
                     /locus_tag="KRN00_002563"
     CDS             14634..15578
                     /locus_tag="KRN00_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBH1828422.1"
                     /translation="MKFLRIEDEVIYSKKRYKLKREIDKLFLDEEYFQIEPQLFEEYD
                     EFTTINNKIPEESMVKVVNGKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKN
                     KNTVGIKEIRQIGCEYLGEASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLE
                     ELNLNKNCENQIKNLLYTKNTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKS
                     NKFYCNNKMKQALEELKQVNNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSY
                     KEILSGGRYDSLTKEYGKEIPAIGFTLSVDELMKYVYK"
     gene            15600..16226
                     /locus_tag="KRN00_002564"
     CDS             15600..16226
                     /locus_tag="KRN00_002564"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBH1828423.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            16260..17309
                     /gene="hisC"
                     /locus_tag="KRN00_002565"
     CDS             16260..17309
                     /gene="hisC"
                     /locus_tag="KRN00_002565"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBH1828424.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            17312..17890
                     /gene="hisB"
                     /locus_tag="KRN00_002566"
     CDS             17312..17890
                     /gene="hisB"
                     /locus_tag="KRN00_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBH1828425.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAKIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            17892..18497
                     /gene="hisH"
                     /locus_tag="KRN00_002567"
     CDS             17892..18497
                     /gene="hisH"
                     /locus_tag="KRN00_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBH1828426.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            18494..19216
                     /gene="hisA"
                     /locus_tag="KRN00_002568"
     CDS             18494..19216
                     /gene="hisA"
                     /locus_tag="KRN00_002568"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBH1828427.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            19198..19956
                     /gene="hisF"
                     /locus_tag="KRN00_002569"
     CDS             19198..19956
                     /gene="hisF"
                     /locus_tag="KRN00_002569"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBH1828428.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            19984..>20606
                     /locus_tag="KRN00_002570"
     CDS             19984..>20606
                     /locus_tag="KRN00_002570"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBH1828429.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGV"
BASE COUNT         8183 a         1946 c         3631 g         6846 t
ORIGIN      
        1 ttagaaattg taaaaatttt atataaaaat tcaaataatt aatgaatatt gaaaatttta
       61 gatatataat aaaataagag tatattttat acaatatgaa agctggtatt gcaatagatt
      121 aaagccttat acacgtttag tttttaaaga aattagtgtt attatgaaaa cctaagttaa
      181 tttattaaat aaataattga ataaaaaaat tttattatgt atttataaaa tttttgttac
      241 aaatttggca taatatagta tactttaagt gtgtattagg ttaaatctat aacaaattag
      301 acgtatgata tagacttagt gtttattggc atttacaaga aatttgttaa tatcaactat
      361 ttgtagtttg ggcagttata attattatag gggggatgtc caatacaaaa caatcaacca
      421 agaactaata ttatattata aagagttata gttttgtgtg tttatgtttt taattaaatt
      481 taaagtggga aaaatatatt tgttagaatg gagaatagcg agatgagtaa taaaatagtt
      541 agtaagagac aattaacaga tagtatttat ttaatggaaa tagaggcacc tagagttgca
      601 aaatcttctc aaccaggtca atttataata attaaaaatg atgaaaaagg agagaggatt
      661 cctcttacaa tagctgacta tgatagagaa aaaggaacag taactattgt attccaaaca
      721 gttggtgctt caactaaaaa gttagcaatg tttgaagaaa acgattttgt aatggatttt
      781 gtagggccat taggacaagc aagtgaattt atacatgaag atatagaaga attaagaaat
      841 aaaaagatat tatttgtagc tggtggagtt ggttctgctc cagtttatcc acaagttaaa
      901 tggtttaaag agcatggatt agatgtagat gtaataattg gtgcaagaac taaagaatta
      961 attatattag aagatgatat gaaaaaagta gctaaaaatg tatatgtatc aacagatgat
     1021 ggtacatatg gatttaatgg aagagttaca gacctattaa aagatttagt tgataatcaa
     1081 ggtaaaaaat acgaccaagc aatagtaatt ggaccaatga taatgatgaa atttatgtgc
     1141 caattaacta aagaactaaa tatacctact atagtaagtt taaatacaat aatgatagat
     1201 ggaacaggta tgtgtggtgg ttgtagagtt agtgttggaa atgaaactaa gtttgcatgt
     1261 gtagatggtc ctgaatttga tggtcattta gttgattttg atcaagcaat gagaagacag
     1321 tctatgtaca agactcaaga gggaagagct atgctaaaac ttgaagaagg cgatagtcat
     1381 catcatagta attgtggatg tggaggtaac aaataatgga tgctaaaaaa gtaaaagtac
     1441 cagttagaga acaagaacct gcagtgagag caacaaattt tgatgaggta tgcttagggt
     1501 ataataaaga agaagctatg gcagaagcta atagatgttt agcttgtaaa aaaccaaaat
     1561 gtgtgggtgg atgtccagta ggaatcgaca taccagggtt tataacaaaa attaaagaag
     1621 atgatataga aggtgctgct aaagtaatag ctaagagcag ttcattacca gctgtttgtg
     1681 gtagagtatg cccacaagaa agtcaatgtg aaggtgtatg tatacttgga ataaaatcag
     1741 atgctgtatc aataggtaaa ttggaaagat ttgtagcaga ttggtcaaaa gaaaatgaca
     1801 taaatttatc tgatacagag cctaagaaaa atcaaaaagt agcagtaata ggaagtggtc
     1861 cagcaggtct agcttgtgct ggtgatttag ctaaaaaagg ctatgatgta acaatctttg
     1921 aagcaatgca tgagccaggt ggagttttaa cttacggaat acctgagttt agacttccaa
     1981 aacaagctgt tgttcaacct gaaatagaca atataagaaa attaggtgta aaaatagaaa
     2041 ctaatgtaat tgttggtaaa acaattacag tagatgaact tatagaagat gaaggatttg
     2101 aagctatatt cataggttca ggagctggtc ttccaatgtt tatgaatata ccaggggaaa
     2161 atgcaaatgg agtattttct gcaaatgagt ttttaactag agtaaactta atgaaggctt
     2221 atagagatga ttatgataca cctattagtt ctggtaaaaa agttgctgta gtaggtggtg
     2281 gaaatgttgc tatggacgct gctagaactg cattaagatt aggttcagaa tcatatatag
     2341 tttatagaag aagtgaaaaa gagcttccag caagagctga agaagttcat catgcaaaag
     2401 aagaaggcat tatatttaat acattaacaa atcctaagga aattttagta gatgaaaatg
     2461 gatatgttaa aggtatggtt tgtataagaa tggaattagg agagccagat gattctggaa
     2521 gaagaagacc tatagaaata gaaggttctg aatttgtact tgatgtagac acagttataa
     2581 tgtcacttgg aacaagccca aatccactaa tatcttctac aacaaagagt cttgatataa
     2641 ataagaagag atgcttaata acagatgaaa atggtcagac ttctaaagag ggtgtatttg
     2701 caggtggaga tgctgttact ggagcagcaa cggtaatatc tgcaatgggt gctggtaaaa
     2761 cagcagcagc atcaatagat gaatatttaa aagcaaaagt taatgcttaa tttgtaaatt
     2821 aaagagaggg tgtctcaaaa tgaacttttt agttcatgag acactctttt tgtacaaaat
     2881 caaatatgtt ttaatcattt caacaatgaa aatttcattc ctgtagaaag tctaactttt
     2941 aggtcttagt acaatctcta ttttgatgta gccacttttt tagatggttt aataatttat
     3001 cagttattat tgtaatattt gatactaagt aacataactt tgtctaacta tgataaaata
     3061 gttatacaat aaaggtcttg taaggagtga ataatgtgtg gctaataaaa tcagatttgt
     3121 caaatctaac attaaataat agaaaaataa attgtgtaat taatggtatt ttaatatgaa
     3181 aaaaagagaa aaagtatttg atgggctagt ttttaagcat atattaatct tattaatact
     3241 attagttttg attgatttaa caagtaccat catatatgca agtaactcta tggaaattac
     3301 ttctagaaat atgattgagg catcaaaaag agaacttgaa aactatttag aagtaaacat
     3361 atctttatta aaagctctta gtcaagatga tagattttct aatggtgaaa catcactaat
     3421 tgaaaaggga aaattattaa gtccatatca aaaggaatat aatcttttta tgattggtat
     3481 aacagataca aaaggaaatg cttcaagtac atatagggaa aatgttaact caataaaaga
     3541 taagcctagt tttgagaaag caattaaaac aaagcaagta gtagtttcag atattgaagt
     3601 cagtaatgta acaggtgaca aagtatttat catatatgta ccaattgtaa aaaataatga
     3661 gatgattggg accatttttg cttcttttta ttttcaagat gtaaataatt taataagtag
     3721 aagcaatttt gatgattcta ttaaatttct aatgatagat aaagattata ctattatttc
     3781 tcatccaaac aaaaaatatg taaatgataa aagtaagatg cttgatttag aagggaatat
     3841 tataggaacc actaaaagtg aaatcttaaa aaatataaat aaaaaatgtc aaggtgattt
     3901 tttatcttgg gataattgga gattatataa tgtaaaatat acgaacataa agtggactaa
     3961 ttggacttta gtatcaaaat gtaatatatt taagaacttt aaaaatctaa tagttaattt
     4021 tatgataaag ttgtattttt atatagtaat atttatgata ttgtggaaat taagtaatgc
     4081 taaattaata gaacaactta aaaaattggc ttattatgat tctttaagtg gaataaaaaa
     4141 taaagaaaag tttagaaaag attctatgta tattttaaag aattattatc aagataattt
     4201 ttacttagta caattggatg tcaataaatt taaatatata aatgagatgt ttggatatgc
     4261 tgaagggaat aagatattaa ttcatatatc acaagtttta aataataata caaataaata
     4321 tgaaatttgt gctaggatgg ataatgacca ttttatattg ttgattgctt gtaacactga
     4381 agatgaactt ttaaatagat tatctaaaat aaataaagaa atttgtaact taaatactac
     4441 taactcatct aagtataaaa ttgttatgtc aagtggaata tataagatta ctaaaaagga
     4501 tgatattaaa aagattgact tgttaattga tagagcaaat attgcagcaa aaagtaaaaa
     4561 ggaaaaatat gaacattcat attcattttt taatgaagat acaagaaatc gattgtacaa
     4621 ggaaaaacga ttggaagata atatgaataa agctttagaa aaaggtgaat ttatagtata
     4681 ttatcaacct aagtatagtt tagatgatgt aaatgaaatt gaaggagcag aagccttgat
     4741 aagatggaat agtccagaat ttgggtttat ttcacctata gattttgtac ctttatttga
     4801 aaagaatggt tttattgtaa atattgatat gttcgtgttt gaagaagtat gcaaaacatt
     4861 aaacaagtgg ataaataaag ggtatactcc tgtaccaatc tctgtaaata tgtctagagt
     4921 tcatttatat agggataatt ttatagaaaa tataactgat ttgataagta aatacaatat
     4981 atctcctgag tttattgagc ttgaactaac agaaagtgtt gtgtttgata atttaaatat
     5041 attgattgat ataatgaaaa agattaaaga gataggattc cttatatcaa tggatgattt
     5101 tggttcggga tattcatctt taaatctgtt aaaagacctt tcttttgata ttttaaaatt
     5161 agatagagga tttttaatcg aaacaacaga tacaaaacgt ggaaaaatta ttatttctaa
     5221 gattgtggaa atggcaaaag cgattgatat taaagtaatc tgtgagggcg tagaaactta
     5281 tgaacaagta gagttcttga aagagatagg ttgtgataag gttcaaggat acttatttgc
     5341 taaacctatg gtattagatg aatttgaaaa acacttaaac tttaaatttg attaatcatt
     5401 aataattatt agactataag ataccctaac aacttactta caaatatgta agttaattgt
     5461 tagggtattt ttatggttaa agtagtatat tcacgatatt atggtattgt agtaaaaata
     5521 aaaaattatg gagaatataa aatgaacata ttgagtatta gaaatatatc aaaaacatat
     5581 tgcggaaata ttccatttaa agcattagat aaggttagtc taaatataga aaagggagaa
     5641 tttgtgtctg ttatgggacc atctggaagt ggtaaatcta ctcttttaaa tataatatct
     5701 acagttgata gacagagtga aggtgaggtt gtattagatg gatatgatgt aagtaaattg
     5761 aaaggagaaa aacttgctga atttagaagg aaacaacttg gttttgtatt tcaggatttt
     5821 aatttgattg acactttaac tgttggcgaa aatattattt tgccacttac actagagggg
     5881 gcaagtatca aagatatgaa tatacaaact aaaagtatat ctaaattttt aggaatagat
     5941 aaaattttag atagaaaaac ctatgaaatt tcaggaggtc aagctcaaag gtgtgctatt
     6001 gctagagcta ttataaataa acctgccata cttcttgcag atgagccaac tggaaatctt
     6061 gattcaaaat ctactgatga tgttttgaaa ttatttacta ggataaacaa agaacaaaag
     6121 gtaacaacac ttatggtaac tcatgaagca tatagtgcaa gttattcaga tagagtaatt
     6181 tttataaaag atggttgtat atatacagaa ataaaaaaat ctgaaagcag taattctttc
     6241 tattctgata tactagctgt tttgtctcaa ataggaggtg taagatagtg gattttagaa
     6301 agtttgctta taataatata gttagaaatt tcagggcata tttagcatat tttttaagtt
     6361 ctgttttttc tataatgata ttttttgttt ttgcagtgtc tatgttccat ccaattataa
     6421 caaaatctgg aatgcagagt ggttctactg catttatggc tcttatgact tcagaattaa
     6481 taatattcgg ttttagtcta ctttttatat tgtactcttt aggaaatttc ttaaaatata
     6541 gattgaaaga ttttggagta ttgatgataa ttggaatgag taacagacaa ctgaaaaaat
     6601 tgatattaat tgaaaatttg ataataggat ttttagcagt gatgttagga atattacttg
     6661 gtttatcaat ttcaaaattg tttttattgt atttaagcaa actgttttat atgaatttaa
     6721 ctgaatttta ttttccagta aaagcaatgc tattgactat tgtatcattt atgattttat
     6781 ttttgataac aggaccaatg agcttaaaat tattgagtaa aaagagcatt ttagagcttt
     6841 tagtaggtac aaaaaagcct aaaaaagaga taaaatcttc aaagctattt ggaataattg
     6901 gtgtaatatg tcttatatta ggatatgcta tgatactatt tggcaataag ttaaaaataa
     6961 atggaggtat gtatacaaca gcactattaa ttactttggg gatattttta tttttttctc
     7021 aatttactat tttgatatta aagtatttaa aaaataaaga aaaattttat aagaacaaag
     7081 taaatatgtt acttataagt aatttgatat ataaattaaa ggataataca cgattgttat
     7141 ttttaataac aatactttta tcggctactt tagtagcatt tacaacaact tcaacacttg
     7201 taagttctca aggagaagct tctaaaaata atttcccaat ggtttactca tatttttcag
     7261 agcataataa tgaaaaagaa tatgaagaac tacaacaaat tagagaagca atcaaaggat
     7321 atgattataa ggagttaagt tttcctgtac ttaaatataa tagggaagtc ttactaagtg
     7381 taaagaatta taacaaatta tcaaaggaat tgggattaga taaaattagt tcaaagttag
     7441 aaaaatatga agggattata attcctagta gcaattcaca agaacatata aattctttaa
     7501 aacaattaaa aaattatagt ataaaaaatt taaatataga agtaaaaaaa tcaaaaaata
     7561 aaataatttt tcctacagga ctgtttagta aagttgtagt tataagtgat gacttataca
     7621 atgaagtaaa aggtgaattt tcaaaaatta attttcatgg atttgattat aaaaactggc
     7681 aaagcagtgc aaagataact gaaaatttaa aagaaaaaca ttttaatttg gatagagaat
     7741 ataacaggtc atatttttta acattaccag atatgtattt agtagagtta caacaaagta
     7801 aaattcttca atttatgggt gtttttatag gagtgatatt atttatagca gtttttagtt
     7861 ttttatactt cagattatat acagacgaga tagaagataa tgtaaagtac aaaaaactat
     7921 caaaaatagg tctatctttt aaaaatatga ataagattgt tagtatagag ataggtacat
     7981 tgttttttat accgtatttt atagcaatta taaatagcat aatttcttta ctgtttttaa
     8041 atcaagtatt aaataatagt tttaagttag aaaatttggg tatattacta ctgatatcat
     8101 ctatatattc actttatttt tacttattaa aaaaaattta tactagaaaa gtttggtttt
     8161 ttgattaaag tggtatataa tagatatata aattaatatt taaaaagtag ttaatattag
     8221 gggagggcat ttgcacctcc cttgtaatat gtggaaaatt gaatattaga agaaggagga
     8281 gacttgatgg aaaatcaaca attattagga acagaacgaa ttagtaaatt actactaaaa
     8341 tattctatac cagctataat aggtatgttg gtaaatagtt tatataatgt agtagataga
     8401 atttttattg gaaatatacc aggggttgga ccacttgcaa taacaggtct tggtgtaaca
     8461 atgccaataa tgacaataat acttgcattt gggatgttga taggtatagg aactactact
     8521 accatatcaa taaaacttgg gcaaggtaaa gtagaagagg caagaaaact tataggaaat
     8581 gcaatgacgt tatctgtaat aacaggaatt atcataatga tacttggaat attatttgca
     8641 aataaaatac ttacattgtt tggagcaagt gaaaatactt taatatatgc aaaatcatat
     8701 atcaatatta tattattagg tacagtagta aatcttcttt ccttttcttt aaaccactca
     8761 ataagagctg atggtagtcc taaaatttca gcaggaataa tgatagtagg atgtttaact
     8821 aatatagttt tagactggat attaatattt ggattcaatt tgggaataca aggagctgca
     8881 attgctacag taacttctca ggctcttaca gctattttaa ctatagggta ttatataagt
     8941 ggaaaatcaa acttacgatt cagtaaatct aatctaaaat tagataaaaa gctaataaaa
     9001 gcagtgtttg caataggtat gtcgccattt gctatgcaac ttgcagcaag tttagttcaa
     9061 gtaatatcaa atattgcact taaaactcat ggtggagatt tagctatagg ggctatggct
     9121 actatttctt ctattgcaat ggtatttttg atgcctatct ttggaataaa tcaaggagcg
     9181 caacctatta taggtttcaa ttatggagct gaaaaatatg atagggttaa aaaagcatat
     9241 ttaggttcat tagtagtagc tactataatt ttatgtatgg gtatggtagt agttatgctt
     9301 ttcccagaag ctattatagg tatatttaat aaagaccctg aacttatgaa tatatctgtt
     9361 aatggattaa gaatatactt acttatgttg ccaattgtag gcttatcagt tacaggaaca
     9421 aactttatac aatctatagg aaaagcaaaa atggctatgt tattgagcct tttaagacaa
     9481 gtaattttat tgataccagc agtattaatt cttcctacat tcttaggttt acagggtgta
     9541 tggacagctc aaccagtgtc tgattttata gctacagtaa ttacaggtat agttgtattt
     9601 agagaattaa aaagatatac tcctaaaact gaaaaattaa atgaaaatga aagactaaac
     9661 gagataacta ctgagtaaaa atataaattc agataattga gcaagaaatt gcaaaaaata
     9721 cgattatatg ataaaataaa accgctgtca aggataagag aaattctaat tatggagtga
     9781 ttttatggaa tttacaaaga aaagcaaatt aaaaaatatg tatgtaaaca tgaatgtagc
     9841 tagaatgttg tctaagataa atgagtataa gggtagacaa ctgctttaca aaaaacaacc
     9901 aaaagaaatt ttagaaaact tagaaaaaaa atctttagta gattgttctg aatctacata
     9961 cattggaaat caaagagata gtagtaattt taatctagaa aagttgataa gtaatgaagt
    10021 tacacctaga agtagagagg aattgagtat tgttgaatac agagatgtgg taaaaactat
    10081 taacagtgct tatgagagta ttcccatcag ttcacaaacg attcttgagc ttcatggata
    10141 cttatataaa ttttcatcta ctagaggagg aagttataag tcagataatg attttattga
    10201 acacaattta aaacctagcg aatttataag tactgattca agtgtcaata aagttgaaaa
    10261 agctgtagaa gaaatatgtg aagcttataa tacattgata gaggaagatg aaattgatat
    10321 attaatatta atttctgcat ttgtgttaga tttcatattg atacatccat tcaaagaagg
    10381 taatataaaa atggcgagag tacttatcct attgttacta aataaaaatg ggtatgaagt
    10441 tggaagatat ataagtttag gaaagatatt tgatgatagt tcatatgaat attatagtaa
    10501 tttaaattat ttgaaagcct caataggtag tgaaaaagca gatatgaatg catggattga
    10561 gtatttttta gagacgatat taactgcata tgagaagctg gatgatagtt taaatatatc
    10621 tgataagaaa agacaaacaa aaactagtag aatagagaaa ataataaatt ctacccttgg
    10681 atattttaca aaagaagata taagagattt atgtcctgac attccagaac ctactataaa
    10741 tagagttttt aataatctaa gaaaacaaga taagatagaa gttgttgcaa gaggaagaag
    10801 tgcaaaatgg aagaaaaaat attaaaaaat gtttagataa ctaaaatggt atagtgtttt
    10861 acactatacc atttttaatg tcattagcat gagcaataat ttaacaactt aagcaatatc
    10921 aattttattt attgattatt tttgaactga aaaatggcgt tatatggtat acctcagtgg
    10981 taattaattt tggatgagaa gatataatat tacagaatat attaggagta tatgtagaaa
    11041 aaatataata aaagtgtgag gcttagtaat taacaaatta tgtggcttca cactttttta
    11101 taaaataaag atacttagca gaataatatt ttagttgata tgtttataag atggtacttg
    11161 tttgggtaaa agtataaata gtaaaaaagt agaagtaatg tgtataaaaa cataagttac
    11221 attctgtaat aatagttatt ttataattca acaaaagaat agaatgggta tatttgtgaa
    11281 ataataatat aaaataatct taggagtgag cttatgaaga aaaaattatt atatataaat
    11341 gtaaattcaa aacctgaaga cttatcttca agtaaaactg tagcaagaaa atttataaat
    11401 aaatttatgg aaaaaaacaa agattttgag gttgaagaga tagaccttta taaagaacat
    11461 ataccaagac ttgagtatca gtactttgaa aaaagaaata gcatagttag tgaagaaaat
    11521 gctaaaaatt tagacgataa ggatagaaaa gagcttacaa agattagaaa tctttgtgac
    11581 caatttgtga gtgcaagtgt atatgtaata gcagcaccta tgtggagttt atcttttcca
    11641 gcaccactta aagagtatat agattgtata attcaagatg gaaaaactat atcttttgaa
    11701 ggcaatgata aaccacaagg aattttaaat gatattgata gaagtatggt atatatacaa
    11761 tcttctggtg gacacatacc atgggtgttg aagccagtta tgaataaagg gttaaattat
    11821 gtggaaagta ttatgaaatt tataggaatt aaaaaatttg atgaattgtt agtagatgga
    11881 actggaacta gtgaagaaga aagacaagct gcaatagaaa aagcatctga aaaaatagat
    11941 ggtataatag atgggatgaa attttaatta taatatttta ttaaaaatat aaaggaaaaa
    12001 cctcttttaa tgtagaaact tatattgaag gaggcgagaa tcatgcgaga agaaaaaagt
    12061 aatgaaaagt atgattgtta ttggtgtaat caagagaata atttctgtgt agaaataaaa
    12121 gataatatag tcatgataga tgatggcact ggtacgttaa aacaagccgt tttcataggg
    12181 tataaacaaa tccaaattaa tttaaactgt tcacattgtc aaaacttaaa tagaataaaa
    12241 ttaaatttgt agaattttaa aatggaaatt attgaaggaa ttaaaaatag aaagtgttaa
    12301 tatttagact gaaaattata ttttatacaa taaaagttta tttaaataac attgtatttt
    12361 aatatttatt ttcagtctta ctttattaaa attatttttt gattatgtct ggaaaatatc
    12421 tgtctactaa tttttctgaa atatttttta attggtcagc cattgaagtc agacttaata
    12481 aggctatcaa taaatcatct ttattttctg gatttatact aatattttca aaattagact
    12541 ctataaagtc cggtatattc tttctttgat tttcttttat taacatgaat ttttcgtaac
    12601 atgaaactaa atctttttca ctgaaattat ccttttcata cacaccatgt aagattcttt
    12661 taatttcttg tattgtaagt gtatttttca tagaataaat aattatcatc tgtaaaattt
    12721 gttctttagt atactttttt cccttaactg gtttgattaa tccctctttg ctgtaattat
    12781 ttatcatggt tttagtaaga attttatcac tttcaaatct tttattagca gaaagcttat
    12841 tgtcaattag agaaataatt tgatccatat ataagtcaat agatggaata tcgtttgaag
    12901 ttatatctgc attatttagt gtttctagta ttatagtatt aagttcatta ttcatcatat
    12961 gttacctcca taatatatat aatacactaa attagaaagt aaaacaatat taaggcttgt
    13021 aaaaaaaaca taaagtggta taattaaata tataatatag taatggaaac tatatttgtg
    13081 aatctgattt ttaaaataca taattgtagg aggacgaaat gtatcaattt tttttaaagg
    13141 gtagagaccc aataagcagt ttaactcatt ttataggtgc ttgtttatct cttttagcaa
    13201 ctataatttt agtttttcaa tctgttacat tacaggaaac ttctctcttg atgatagtat
    13261 ctgtatcagt atttggactt tcactaattg ctttatatag tgcaagttcg tattatcatt
    13321 ttttaaaggg gacaccagaa caagaattgt tttttagaaa agtagaccat gcaatgattt
    13381 acgtattgat tgctggctct tatacaccaa tatgtctgaa ttttatggaa aaaaaagaag
    13441 gcataatatt tgttacagca atatggatag ttgcatttat tggcataata ataaaaatat
    13501 tttggatgga tgcacctaga tggttatcta ccagtatata tttacttatg gggtgggcaa
    13561 ttgtttttga tataaatgca ttcaattcaa ttcctaagga ttgccttaga ctattaatta
    13621 tggaaggtgt atcttactct ataggtgcga ttatttatat aattaaaaag cctaatataa
    13681 gtcctgagtt tggatttcat gaaatattcc atatttttat tatgataggt tctttatttc
    13741 actttttagc agttttattg tatgttttat agttttaaaa gatttgatta attgatacta
    13801 aaattctaca atgaataaaa tggaactgcc ttatatagat tatatcttcg acaataagac
    13861 agttccttat tataaatatt aaattctact tataataaaa ttttgataaa aatagtccat
    13921 tcaaaatgcc tattccataa ttcctttaat gtacttttca tttacgacat atagtttgaa
    13981 tttatgtact ataattatat cctctaaatt ctctgaaaca ctaacaattc tgacacattt
    14041 gtttctaatt tctacaggta aatctaaatc atttgttaaa ttcacatagt catcatattt
    14101 atacataaaa tcatcccttt acattaagat atacttatta tactatattt taataagttt
    14161 ttttaaatta ttacaatttt tcccgaaatt tcatttttta tacataaaat ttccaaatta
    14221 ggtaaagatt aaatttttta ttgtataaac aaaagttaca tataaaatat tttattcaat
    14281 tttttaaata actattgcca atttttgaaa aatatattat tattaatagt aacaaaaaac
    14341 tgtaaattta gaatattaat aaaaattatt tgggaggaaa ttatcatggt gagattaaat
    14401 atagtaaaat taaatacaaa attaaatcat caccatcatc atagattaaa gggattgtaa
    14461 tatgaaatta attcatagac acaagccctg tttttagtgt aattggtctt gtatctatga
    14521 tgggaagtaa ttttaagaga aaattatagc catataggta taaagcctat gtggcttttt
    14581 tattgtttta aatttgcaaa tataagagta aatttaatga agagggtgag aatgtgaaat
    14641 ttttgaggat tgaagatgag gttatttatt ctaaaaaaag atataaatta aaaagggaaa
    14701 tagataaact ttttttggat gaagaatatt ttcaaataga accacaatta tttgaagaat
    14761 atgatgaatt tacaactata aataataaaa ttccagaaga atctatggta aaggttgtaa
    14821 atggaaaagt aatggtactt agagctgata taactacaag tataataaaa agccttgtac
    14881 caagatggga agatggttta aagcttaagc ttttttataa ttcatcaata tataaaaata
    14941 aaaatacagt tggaataaaa gagataagac aaataggttg tgagtatcta ggagaagcct
    15001 ctgtagaagc agatagagaa gtagtgaaat tagctcttaa gatacttgaa aaatacaata
    15061 ataattttat tctagaggtt gggagtagca agtatattca tggtttgtta gaagaattaa
    15121 atttaaataa gaattgtgaa aatcaaatta aaaatttact atatacgaag aacactcatg
    15181 aactaaaagt atatattgaa gaattaaaaa ttaagcgtga agtaaaagag ttattatcaa
    15241 atattttaag tttacaaggg aatttatata atgttattga aaaatcaaac aagttctatt
    15301 gtaataataa gatgaagcaa gctcttgaag aattaaagca agtaaataac ttgattgagg
    15361 aatgtaattt tttagataag gctagatttg atttatcaat gattactatg cttgactatt
    15421 atgaaggaat tatgtttaga ggatactacc caaactcata taaagaaatt cttagtggcg
    15481 gaagatatga ttctttaact aaagagtatg gaaaagaaat tccagccatt ggatttacac
    15541 taagtgttga tgagttaatg aagtatgtat ataagtaaag tttagaagga gggattgttt
    15601 tggattattt gactatagca ctagcaaaag gacgaattga aggggaatca tttaaaaaat
    15661 ttaaaaaaat gggtctagga gatagtatag acacagatac gagaaaacta atttttaaag
    15721 atgaagaaaa taaaattata tatatacatg taaagccatc agatgtagtt acatatgttg
    15781 aaaaaggagt cgctgacctc ggtatagcag gtaaagatac tattttagaa aatgagacag
    15841 atgtatatga aatatatgat ttaggttttg gaaaatgtaa atttgctgta gcaggattaa
    15901 agggagatag catatataga gaagatgaat atttaaaagt ggcaacaaag tatcccaata
    15961 tagcaaaaaa gtattttaaa gagaaaggtc aaaaaattga aataataaaa ttaaatggtt
    16021 ctgtagaact agctccaata gtagggttgt cagatgtaat tgtagatata gttgagactg
    16081 gcaatacact taaagcaaat ggtcttgaaa tattagaaga catatgtaat ataagtgcta
    16141 gaattatatc aaatagagct agctatagat ttaaatatga acaaattcag aatataattc
    16201 gtttatttga agaacttgat aattaaaata taattgagct ttataaggag ggatttaagt
    16261 tgagagaaaa agaaagcata agagagttaa ggggatatga accaaatcac gtaaactgta
    16321 aagtaaaact tgatgcaaat gaaggaagta agaggttgtt taaatacctt attaaagaaa
    16381 tttcagatag tgatatagat ttaaatttat atcctgaaga ttcttatagt gatttgaaag
    16441 aatctataat agattacata aatatttctg gagtaaataa gaaaaatctt ctagtaggaa
    16501 acggttcaag tgaaataatt gatttaataa tacatacttt tgtagataaa gatgaagtaa
    16561 tattgagttt ctctccaagt tttagtatgt attctatata tagtcagata aatgggtcta
    16621 aatttatagg tgttgaaagt gatgaaaatt tagttataaa tatagataat gtgattgaaa
    16681 aagtaaagga gaataatcct aaaatagtaa ttgtatgtaa tcctaataat ccaactggaa
    16741 caatattaaa gagggaagag ataataaagc ttttagattc aactaatagt ctagtggttt
    16801 tagatgaagc atatatggat tttggagaag aaagcatgtt aagtgatgtt tttaagtatg
    16861 ataatctaat agttcttaga actttatcaa aggcatttgg attggctgga ataagaacag
    16921 gatatatgtt atctaatagt agtttaataa attctgttga gaaagtaaga cctccatata
    16981 atttaaattc attatcagac tttattgcta caagagcact tagaaataaa gatgtggtaa
    17041 aagcttatat aaaggaagta aaagaggaaa gagaagtttt atatgaagaa atgattggta
    17101 tgggaattaa agcatacaaa tcacaagcaa attttatatt attttattct gaaatcgaaa
    17161 atttatcaca aaaacttatt gatagaggtg ttttaataag aaaatttggt ggaaagttag
    17221 aaaattatta cagagttaca attggtgata aagaagaaaa ttctatgttt gttggagcta
    17281 taagagatat tttgaaaaag gagaaatagg tatgagaatt tggaaggtag aaagaaatac
    17341 tcttgaaaca cagattttag tagaattaaa tattgatggt tctggtaaag ctaaaataga
    17401 tactggaata ggatttttag accatatgct taccttaatg tcatttcatg gcaagttcga
    17461 tttaaaagtg atttgtaagg gtgatacata tgtagatgac caccatagtg tagaagatat
    17521 aggtatagct ataggtgaag catttaaaaa tgctctaggt gacaaaaaag gaatacgaag
    17581 atattctaat atctatatac ctatggatga atctctatca atggtagcaa tagatataag
    17641 caatagacct tatcttgtat ttaatgctaa atttgatacc caaatgattg gtagtatgag
    17701 tactcaatgc tttaaagaat tttttagagc ttttgtaaat gaatcgagag taacattaca
    17761 tatcaatctc ttatatgggg aaaatgacca tcataagata gaaagtattt ttaaagcatt
    17821 tgcaagagct ttaaaagagg gtagtgaaat agtttctaat gagatagcat cttcaaaggg
    17881 ggttttgtag aatgaatata atagtagact atggtcttgg aaatatagat tctgtgtcta
    17941 ggggttttag aaaagctgga atagaaacta aaatttctag tgatatagat gaaataaaac
    18001 aggcagattc acttatactt ccaggtgttg gagcttttag agattctata agtgccttag
    18061 ataaactagg attgatacca ataataaagg agcatgtttc taagggtaaa tttatgatag
    18121 gtatatgtct aggaatgcaa ttactttatg aaaaaagtta tgagtatgga gaatatgaag
    18181 gattaggact tataaaagga agtattgata aactggatat aagtttaaaa gtgccacata
    18241 tgggatggaa taatctaaaa tttaataagg caaatgatga tatacttaaa tatataaatg
    18301 aagatgatta tgtatacttc gttcactcat attatgcaaa ttcatcaaat gaagaactaa
    18361 ttgcattttc agaatatgaa aagaaaatcc ctgctattgt tagaaaaggc aatgtatatg
    18421 gtatacaatt tcatcctgaa aaaagtggag aagtagggtt aaatatatta agagcatatg
    18481 gggagatgat aaaatgataa tatttccagc aatagatata aaagataata agtgtgtaag
    18541 actcacacaa ggagaatttg acaaagtaaa tgtatattat gataatccat tagaagtagc
    18601 atataaatgg aaaaatgaag gagcagaata tatacatata gtagatttaa atggtgctag
    18661 aagtgaattt ggtgtaaata caaaaataat tgaggacata gcaaacaata tagatatacc
    18721 tattcaagtt ggcggtggag ttagggataa ggaaaaagtc aaaagtttaa taaatgctgg
    18781 tgttactaga gtaatattag gtagtatagc gattgaaaat ttgaatttag ttgaagaatt
    18841 ggtcaatgaa tataaagaga aaattgtagt ttctatagat gctaaagatg gaaaagtagc
    18901 agttagggga tgggaagttg taagcaatgt agactcatta acattatgta aacaacttga
    18961 aaagataggt gtacaaacta ttgtttatac agatatatca aaagatggga tgttacaagg
    19021 tccaaatttt gatatatatg aaagaatagc aaaggaaaca tcactaaatg ttattgcttc
    19081 tggaggcgta acttctatag aagacgtaaa aagactaaaa gctatgaact tatatggtgc
    19141 aataataggt aaagcgcttt atgataaaaa gatagacttt aaggaggcac aacaattatg
    19201 cttactagga gaataatacc ttgtctagat gtgagaaatg gaagagtcgt aaagggaaaa
    19261 aaatttaaag atatagtaga tgttgatagt ccagaagtac ttggaaaatt ttatagtgat
    19321 tgtggtgcag atgaacttgt attctatgat ataactgcat caaatgaaga gagaaagaca
    19381 tctttagaat ttgtgacaaa agttgcagaa aatataaata taccattttg tgttggtgga
    19441 ggagtaaata aattagaaga tttcactgat attttaagaa aaggtgctga taaagtttct
    19501 ataaattcat cagcagtcaa aaatcctgaa ttaataaggg aagcttcatt aaaatttgga
    19561 gcacaatgtg ttgttttatc gatagatgca aagaaaaatg aagagggttc atggagcgta
    19621 tacgtaaaag gtggaagaga aaaaactaat ctggatgcaa ttgaatgggc tgttaaaggt
    19681 gtagaacttg gagcaggaga aatcgttgta aatagtatgg atgaagatgg aatgaaaaat
    19741 ggatatgata tagaattatt atcaaagata acttctttag taaatgtacc tgttatagca
    19801 tctggaggcg ctggaaaaaa ggaagatttt tatgaggcgg ttaataaatc caatgtagat
    19861 ggaattttag cagcatctgt ttttcatttt ggcgagataa aaataaacga tttaaagaaa
    19921 tatttaaaag acatgggtgt agaagtaaga ttataagtta aatactaaaa ggagattaga
    19981 aatatggata ataagtgtaa caatgtatac agtgatgaag tagagaaatt tataagaagt
    20041 ataaagtttg atgataaagg gttagtccct gttgttgttc aagaggtagt tagcaaagat
    20101 gtactgatgt tagcatatat gaataaagat gctataaaga aaaccttaaa agataaagta
    20161 gcttgctatt ttagtagaag tagacaagaa ctttgggtta aaggtgagac atctggtaat
    20221 actcaaaaag tagttaagat gtcttatgat tgtgatgtag atactatact actttttgtt
    20281 gaacaaactg gtgtagcttg tcatacaggc aattattctt gtttttacag agacttgttt
    20341 gatgatagtt caaaaatgga gcttgaagta caaacaaata tattgaaaga attatatgat
    20401 ttaatcaatg aaagaaaaaa taatccagtt gaaggttctt atactaatta tctttttgaa
    20461 aaaggaatag ataagattct taaaaaagta ggtgaagaga gtagtgaggt aattatagca
    20521 tcaaaaaata ctgataaaag tgaacttatt tacgaaatta gcgatttagt atatcataca
    20581 ttggttttaa tgatagaaaa aggtgt
//
LOCUS       DAEQAF010000068        20604 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.070, whole genome shotgun sequence.
ACCESSION   DAEQAF010000068 DAEQAF010000000
VERSION     DAEQAF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.070"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            272..1537
                     /locus_tag="KRN00_002571"
     CDS             272..1537
                     /locus_tag="KRN00_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBH1828430.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVIVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            1576..2031
                     /locus_tag="KRN00_002572"
     CDS             1576..2031
                     /locus_tag="KRN00_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828431.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(2175..2546)
                     /locus_tag="KRN00_002573"
     CDS             complement(2175..2546)
                     /locus_tag="KRN00_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBH1828432.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(2549..2917)
                     /locus_tag="KRN00_002574"
     CDS             complement(2549..2917)
                     /locus_tag="KRN00_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBH1828433.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            complement(3187..4065)
                     /locus_tag="KRN00_002575"
     CDS             complement(3187..4065)
                     /locus_tag="KRN00_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1828434.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIISGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            complement(4082..4399)
                     /gene="trxA"
                     /locus_tag="KRN00_002576"
     CDS             complement(4082..4399)
                     /gene="trxA"
                     /locus_tag="KRN00_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH1828435.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            complement(4549..5781)
                     /locus_tag="KRN00_002577"
     CDS             complement(4549..5781)
                     /locus_tag="KRN00_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828436.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            complement(5771..6442)
                     /locus_tag="KRN00_002578"
     CDS             complement(5771..6442)
                     /locus_tag="KRN00_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828437.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            complement(6458..7294)
                     /locus_tag="KRN00_002579"
     CDS             complement(6458..7294)
                     /locus_tag="KRN00_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828438.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            complement(7320..7994)
                     /locus_tag="KRN00_002580"
     CDS             complement(7320..7994)
                     /locus_tag="KRN00_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1828439.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNIKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            complement(8008..8736)
                     /locus_tag="KRN00_002581"
     CDS             complement(8008..8736)
                     /locus_tag="KRN00_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1828440.1"
                     /translation="MMFDRVKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKTLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            complement(8863..9552)
                     /locus_tag="KRN00_002582"
     CDS             complement(8863..9552)
                     /locus_tag="KRN00_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1828441.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNDFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKEMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            complement(9560..10123)
                     /locus_tag="KRN00_002583"
     CDS             complement(9560..10123)
                     /locus_tag="KRN00_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1828442.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPL
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            complement(10125..11093)
                     /locus_tag="KRN00_002584"
     CDS             complement(10125..11093)
                     /locus_tag="KRN00_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBH1828443.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLYNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     regulatory      complement(11194..11237)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11602..12231
                     /locus_tag="KRN00_002585"
     CDS             11602..12231
                     /locus_tag="KRN00_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1828444.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKSIMYSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     gene            12206..12610
                     /locus_tag="KRN00_002586"
     CDS             12206..12610
                     /locus_tag="KRN00_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBH1828445.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKAVENALRKGE"
     gene            12613..13089
                     /locus_tag="KRN00_002587"
     CDS             12613..13089
                     /locus_tag="KRN00_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin domain-containing protein"
                     /protein_id="HBH1828446.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNNKIELS
                     KFDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPS
                     SLLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            13659..14324
                     /locus_tag="KRN00_002588"
     CDS             13659..14324
                     /locus_tag="KRN00_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBH1828447.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            14346..15278
                     /locus_tag="KRN00_002589"
     CDS             14346..15278
                     /locus_tag="KRN00_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBH1828448.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKSATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            15299..15940
                     /gene="pcp"
                     /locus_tag="KRN00_002590"
     CDS             15299..15940
                     /gene="pcp"
                     /locus_tag="KRN00_002590"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBH1828449.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(16060..16392)
                     /locus_tag="KRN00_002591"
     CDS             complement(16060..16392)
                     /locus_tag="KRN00_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1828450.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            16658..17278
                     /locus_tag="KRN00_002592"
     CDS             16658..17278
                     /locus_tag="KRN00_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1828451.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNKLIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            complement(17603..18427)
                     /locus_tag="KRN00_002593"
     CDS             complement(17603..18427)
                     /locus_tag="KRN00_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBH1828452.1"
                     /translation="MDFFKKGISGFTIKILALIFMTFDHIAAFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(18438..19841)
                     /locus_tag="KRN00_002594"
     CDS             complement(18438..19841)
                     /locus_tag="KRN00_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828453.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NNPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            complement(19845..20570)
                     /locus_tag="KRN00_002595"
     CDS             complement(19845..20570)
                     /locus_tag="KRN00_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828454.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDVQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKIREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
BASE COUNT         7150 a         3178 c         2346 g         7930 t
ORIGIN      
        1 tagatatatt taatatttta taattgttat tggatacaat aaattctagt ttaaagggta
       61 tattttttcg tttgtcgttt aatattatta tcaatggaat aattttaaaa tttatttaaa
      121 taacaaaaat tttctttaaa ttctgtcaat ttttcaaaaa ctttgttaaa taatatactt
      181 tcatacatcc attgaaaaaa caataaaaaa gtaatactat atatagtact agcattaggc
      241 acaaaataat acaaatggag gtacttatat tatggaattt caacaaataa tagctatatg
      301 tatattttta atagttatgg cagctattat tacagaaaag gtaaacagat ccgtagcagc
      361 tgttggtggt gcactattaa tgataatatt caatatactt acacttgatg aaggattaag
      421 ccatatagat ttcaatacta ttggtgtatt agttggtatg atgctatttg tagctgttgt
      481 caaaaactcg gggttatttg aatatatagc tatctggact gcaaagaaag ctaaaggtga
      541 cccatggaag ataatgattt gttttgctat tataacagct attttatcag ctgtattaga
      601 taatgttaca accgtcttac ttattggacc aatgactata gttattacac aaatattagg
      661 acttaatcca gttccatttt taataacaca gattttagct tcaaatatag gaggaacagc
      721 tactcttata ggagaccctc caaatattat gattggtagt gctgccaatc ttagttttat
      781 ggattttgta ataaatttag gtcctgctgt tatagtaata cttgctataa ctataatatg
      841 ctttagattt atttatggaa aagaacttgt tgtgaatgaa agagctaaaa atgcaatatt
      901 aaaactagat gaaaaaaaat ctgttaaaga taaacctcta cttataaaaa gccttatatt
      961 aatagcattc atactttttg gttttatgtt tcacagtaca atccacatag attcttctgt
     1021 tgtagcactg acaggagcat ctataatgct tttaatagga aaacaagatg tagatgaaat
     1081 tatggcaggt attgaatggt ctacaatttt attctttatg ggattatttg tagtagttgg
     1141 tggattagta gaagttggga taataaacaa attggctcaa gcattgattg gacttacaga
     1201 aggacatctt gtatttacaa tgttgttgat attatggtta tcagctatag tctcttcttt
     1261 cttagataat attccatttg ttgcaacact aattcctctt attttgacta tgcaagctga
     1321 aggtattgat gtaatgccac tatggtgggc aacatctctt ggagcttgtc ttggaggaaa
     1381 tggaacacta ataggagcat ctgctaatgt tgtactagca ggtataggta ataaacacgg
     1441 tcatcctatc tcttttaagg agtatttcaa aataggtttt ccacttatga ttatatctat
     1501 tattatatct actgtttatt taattataaa attttaaaaa atatagtata ataatactaa
     1561 aggggatgtg tatatatgaa tattaatact gttcaaggtg attcgattga agttctttta
     1621 agacagcttg gtgccacaag aatatcaaaa gtaagtagta cattatattt tatcaagttt
     1681 gatttaggag acggttggga aatatcttat acttataata ttaatgctaa agaccaatat
     1741 tttttacaga gaattgaacc atatcctatt ggtagaggtc tatttaatga tgaatatgaa
     1801 atagtatcat ttatatcaaa ggatttaaaa aaatttctaa atgctaaaaa tagtagtaac
     1861 tttaagacat ttgttgaagt tactagaaag gtcaattcta tcattgataa tgtagaggaa
     1921 ctatttttaa actacaatgt agatggtgat gatttaaaaa cacttaataa agaactcaat
     1981 gacatattaa atgatattga ctatatagaa aaacatacaa aaaaaatcta aaagtagtaa
     2041 acttgtaaac ttgaaatatt attaaggata ctacaaaaaa cataaaaatc taaattttgg
     2101 ttttaaaaga ataaaatcgt atttattaaa agaaaaaata gctgatgaag tatatatttc
     2161 atcagctgtt ttttttaatg atgtccacat ccgtcatgtg agcaagtatg gtctgatgga
     2221 aactctacta attttccatt tttaagtaag tctaaattag cacttatagt atcaccttct
     2281 gctctgtaaa cttttattcc cattccattt aatttaatta tagctccttg tcctattcct
     2341 ccaacaacta ctgcatctac agctgtccct gacaatgctt ttaatggttg acattttcca
     2401 tgttcatgat ctaaatctcc attatctaaa gatttaactt ctccactttc taaatcacac
     2461 acaacaaaaa ttggagcaga accaaaatgt ccatatggtt tactatccaa tcctttattc
     2521 tcctctactg gtatacatac tttcattatt atttctccct tctcttacaa cattttttta
     2581 tagatttaca ttctttactg catcctagat gtattgtatt tacatcaaat acatctataa
     2641 agctttcact agaattactt aacatagaat ttataaaatc tacacatata ttaaatgatt
     2701 ctttattaat atgatataaa acatagtatc cttctttata tcctgttatt atcccaacat
     2761 cttttaatat ttttatatgt tgtgaaacag cagaatctga aatccctaga tatttagaaa
     2821 tccccttttg acatatattt ctcttggata ctaatataag tatgttaagt ctagtttcat
     2881 cactcaatgc tttaaatatt ttaaccaagt tttccataag tacctcgttt tgattaagta
     2941 attacttaat taaattatag tactcttaat tagatttttc aaccattatt ttaaaatttt
     3001 ggagtatatt ataaataatt ccaattttta ctaatataac tttgagtttt attaataaaa
     3061 gtaattacat atagatttta aaatactttt attaataact taaaaataaa aaactgtctt
     3121 gaaataataa aattatttca agacagtttt ttataaatat ctttaaaaag ttaatcaata
     3181 taaatattaa gccctcttta atttatctaa atagtaaaca gcatttaaag ctgctatttg
     3241 cccttgacca gctgctttta tataagaata tggttttcca acacaatctc cagcagcaaa
     3301 gcatccatct atactagtct tcatattatt gtcaacttta atatgaatgc catcaatctc
     3361 tattccagga accaatgcac ttggagccgt actatctttt ataacgaata ctccatctac
     3421 ttcaatgtgg ttttctttaa aagatacttt gtttacaagt ttatctccat ctatctgtac
     3481 tggtctgtca tgtataactt caatagaatc atctaggtta tctgaacttc tcataagatt
     3541 atcttttttg tacataggta taaaataagt ctttgaagtg agttcactta aaaaatttgc
     3601 ttcttcttta gattcttcat tatatcctat aactgctacc tttttatttc tataaagtgg
     3661 tgcatcacat gtagcacagt agcccacacc tcttcctaga aattcttctt cacccttgat
     3721 tggtctagta tactctaccc cagttgcaag gattacagta gtagcttcat acatatcatt
     3781 tccagatatt attgtaaagt attctcccat agcataaata ttatttattc ttttattttc
     3841 aattgaaata tccatactat ctatatgtga tttaaacttg tcttttaatt catcaccact
     3901 tatatcataa aaacctaaat aattatctat tgaaggagct ttaacaagct tattacttaa
     3961 attatcatta ccaaacatga taattgtttt atttcttatt tttgcattta tagcagcaga
     4021 caatccagct ggaccactgc cgattatagc tatatcatat ctcataatac tcacccattt
     4081 tttataaata tgattttact tgcatttcaa ttttgttctt tggcatgaat ccaattaaag
     4141 tttctactgg ttttccatct ttaaatataa tcatagttgg tactgtagat acattgaatt
     4201 gttgagctat ttctaagctc tcatctatat caacttttac aaatctagct ttatccttca
     4261 tctcttcacc taattctgca aatacaggtc ccaacatgtt acaaggtcca caccaagttg
     4321 caaagaaatc aactacaact actcccttac taccttcaac actacttcta aattcagatg
     4381 tatttataac ttttgccatt tttaaatcct cctattaaac tttattatcc ctatataatt
     4441 atactatgaa atttataaat ataaatttac ttttataagg tctttttata ttttatacta
     4501 attagtatac ccattcttca tttctaaaaa caatttttta tatttttatt attttaactt
     4561 ttttggtatt gacaattcaa atgtagttcc aatatctaca tcagaagtta catttatatc
     4621 aatagataag tttaaactaa tcatgcgagc tattgaaagt cctattccag aaccttctaa
     4681 atctttattt cttacatttt cacttctaaa aaatctatca aatataagag gtatctcttc
     4741 tttttttatg cctataccag tatcacttat aagtaaagtt acctcatcct ctatatcttc
     4801 tttcaattct aatgctatct catcacccaa ttttgtatac ttaaaggcat tatcaataaa
     4861 aattaatata agttgtctta atttattttt atctgttatt ataactttat tcttcagttt
     4921 agaattaaag acgaatcttt tttcctgaaa ctcagcaatg tcaatatagt cttctgatat
     4981 ttcttccaat aacttttcta aatctatttc ttctaaatta actttaacaa tagagtcctc
     5041 tttagtaaga gacaataaat cagttatcat ttttttaagt cttctagttt ccttcattgc
     5101 agtagctatt gtttcaactt catcatttac tgtactttct ggggatttta acatactttc
     5161 taattttgat gaaactattg ttattggtgt tcttaattca tgagaagcat cttgtataaa
     5221 cttagcttga tttttccatg ctgtttctat tggaattaaa gcttttctag tgagatatac
     5281 agccacaaag taagtaatta ttacagaaat taatattcca attataagaa cagatgtaag
     5341 ctgtcttaaa gaattcatct cagaatctat atttctaatt atctgtattt ggtatctacc
     5401 tacatctaca tttaattctc taaaagtata tccattttct gtgtatttaa aaaacgaatt
     5461 ttttttatct agtcttctat ctggaagtaa ctcatcaaaa tattcatttt gagtatagta
     5521 acttatcctt ccatcttcat atacatacac catatcttta ggatctttca gtcttattgg
     5581 gttcaaaaat gaagttcttt taaattgaga gactatatat tcaagttcat catttatctc
     5641 actatcaatt ccactatatg taagtcccct aaaatatgag tatataaata tagaaaagat
     5701 tattaaaaaa ctacctacta caataatata catttttatt aaatgatttt tagtactggt
     5761 aaatacattc ttatttatca tcgaatatat atcctacctt acgtttagtt ttaatatatt
     5821 tatcatatcc atatttactt agcttttttc ttagattact tacatatact tccactattt
     5881 caatagttgc atctgaatca attccccata ttctatcata aatctgctct tttaataaaa
     5941 ttgaaccttt atttaataca aaatactcaa gcaagttaaa ctgtttgttt tgaagtttta
     6001 tttcttcttt ttcaatatac actctttttt ctagtgtatc taaatataaa gatttaaatt
     6061 ctaatccgtt tctttctttt atctttccat tagtccttaa tatagcgtat accctagcta
     6121 ctaactcttc catataaaaa ggttttgtca aataatcatt agctcctata gtaaatgctt
     6181 ctactttgtc atctaatgtt tcttttgctg tcaatataag tacaggtgta tctatattat
     6241 taactctcat tttctttagg atatcaaatc catttatatt aggaagcatt aagtctaaaa
     6301 tgactaaatc atatatattt tgatttacta agtataaagc ttcttctcca tcttcacact
     6361 tttcagtttc aaaatgcttg ctaagttctt ctactacact ttctaaaagt atcttattat
     6421 cttcaactat taaaaccttc ataagtatcc cctaccttta tttgtctatc ttaactttat
     6481 gagattttaa gtcaatatcc acattggctt tttcttttat atcatcatac gtatatccca
     6541 ctatttcaac actttttgcc tttgttgaac acaatatatc tatatctgtc tcttctgaag
     6601 gctttaaaat cttatatgat ggcacacgat ttactgttaa atattctcca ttttcattaa
     6661 cttctgctgt cttaagaata atatttccta aatcttttga tgatgaattt tttactttta
     6721 cttgatacgt aattccctca tttgattcat ttactttttt aagttctgat gtagatagca
     6781 cctcatactg actactattt tctagcttaa tattattatt tcttatatta atagtatttt
     6841 cttttaaatt aacatacaca atcttaccct ctgcctcata ttcatatgca taaacttcta
     6901 caccctttac aaaagtttta tgcccacatt ctatgtaagc aactttccca ggcattaaag
     6961 tcatgtccaa caaagcctta ctatccgaag atataatttt tttattctca tcatattcat
     7021 tatatatcaa ttcaacattg gatatattaa atgttgaatt attttctacc tttgttgatg
     7081 tatctacttt atcaccttca tctatattta taatttctga ttttcctata ttcaatactt
     7141 ttgcatttcc ctcatctatt tttatctcat ttttatcttc tgtttgaata tcaactgaat
     7201 caggctgttc atctttttca catgctgtca acataaaaat aaatattgtt aatataatca
     7261 ttagagaaat tgattttttt actattttat tcatattaag cacctcatat agtagtattt
     7321 tatagtagat ttttatactt tttcataaat tctttcaatg cctgtgtaag tatttgatgt
     7381 ttttcaaaat tcgaattact acataatctt tcaaaatcat tccatatttc tttatctata
     7441 cgtattcttg ttgtttttaa ttcatctatg tgttcatcat ctatatgtac atctttttta
     7501 ttagatactt ttttaggctt tatattgtaa tcttttactt ctaaatacca atcatatact
     7561 tcacaaagct tatctaaatc ttcttgagtt atatttattt ttctatcttt cttaggctta
     7621 atattttgtt ttggctttgc attttttaaa cctgtatcat taaactcaat ttgttcaaca
     7681 cttttactta aagccttttc attagaaatc ttttttttgg tgcttacttt ttttctatta
     7741 cttatagtat tctttttact tttttcatac tccttagctt tctcttcttc caagtttcta
     7801 ttatccaaac ttttattata atttaattcg tcttttaata tgtatttacc tttttctgac
     7861 ttatatcctt ttttatttaa aaaagttctt aaagtacttt gactaatctt tagattttga
     7921 gctatctctg caaatttaaa tcctttgctt tgaagttcta aaaatttgtc aattctgtct
     7981 tcattgttat tcattaatat tcctccgtca acatcttctt gtctttcttt tcatacttct
     8041 tattatattc ttcttttcta aatctactct atttgattca attatttttt gtagagtttt
     8101 attataagtg aaatcatcta aattattatt ttttatatag agaaaagttt cctcttcaca
     8161 tttaataaaa caaattgata gcaaccatgc catacccatt ttaacataat attcttcact
     8221 ttgtatatta ttacagtatt caaatatttc tttaatatgt ttatcatcaa cataatatat
     8281 taaaaacata actaatgcaa atctaatttc ccatggattc tttgaataaa catatttttt
     8341 aagtatatca tacatatttt ctttatattt tttcatagac tttaaatcag aacaaaatcc
     8401 atcgcaaact gaccaattat cgattttagg tataaatctt tttacatagt ataaagtttc
     8461 ttcaaaatta ctatttatat tgccaattac cataccttgt agcctaactt cttcatagta
     8521 tgtatcctct gctacttcta aaaattcctt ccaattccct tggcttattt cttttgataa
     8581 ctttcttaaa ttaggaactc taatacctat tatattttct gttccaggta taagcttttt
     8641 attaaaatct ctatatttta tatcttgtat agacatcata tattctaaaa gttcattata
     8701 atccaattta ttccatttta ccctatcaaa catcatttaa ttgctcctta attccttttt
     8761 tcttattgta acataaaact ctacaaaaaa agcttctaac tattagaagc tttttcaaaa
     8821 acataagaaa cttttcaatt ttaaatttaa actaaattaa tgctaatctc ctacaccaaa
     8881 atctgtatta ttgtataaaa cttctatatt tggattttca tccaagaatt tatacttact
     8941 aacaaaccat ttcactaact cttcatctct ttttatacta gaagaattat ttataaaaac
     9001 attcactgtc gctttttcaa aagtatttag gataatctct atatctttat ctatcatctc
     9061 ttttgtttgt ccttttattc caaccataat acaaggtgaa tcaaaatatt cttttacatc
     9121 ttgtggagtc ttaaaatttg catttttatt taaaatatta tttctaaaat cattgtcaaa
     9181 ggtttcaact ccaattttaa ataccacagg aatttcaaaa tactctctca tttccttaag
     9241 cctatttttg taagaccaat gactttctaa aaataatttt tttatatttt tctcttttat
     9301 aatacacttt attttttcta aagtatcctt aggtaattca aaacagcttc cagaatttat
     9361 gacttcaaga actccatatt tcccagttac gttttttaaa acctttagat ttaatttatt
     9421 catctcttct tctaaattag aattatcatc tatataatca caaaaagaac actttcccca
     9481 tatacaagga aatcctttaa gcagaacaat ttctctttga tttttatttg ttatctcact
     9541 atatctatcc attttctatc tattttcctc cagtcaatga tacctttaaa gtttttggaa
     9601 ctgcatttaa tcctaaattc actaaaacaa ctgctaacag cttatctcca taatcagtaa
     9661 atacttgggt tacaaacaca ctaaaaacat cccccagtcc taacactttc aagatttgca
     9721 ctatatatga tgaacctgaa gaggtcatac ctccaaataa aaatgctgaa attattgaac
     9781 ttattataga tgttggaatg gcaaataaaa gtactcctag tggagttttt aaacccctta
     9841 aaaaattctt tttaaatgct attccagcaa gtaatccggt tgatatttga actggtgcaa
     9901 aatagagaga atacacatca aacgtaattc cacttattaa acttccaaac acacctgtaa
     9961 caacagcgta tttaggtcct aaaagtgaag ctatcattat agttcctatt gaatctaagt
    10021 atacaggtaa tcttaatccc atagctataa aagcgcctat tatatttata gaaataccaa
    10081 aagctataag tgtaatagtt tttacacata tttttctttt cacactatat cactccttcc
    10141 acagagtcta taatgtcttc ataaccttta aaaagcctct ttaaaaacat gtacataaat
    10201 ttcttctcat caacttcatt tagaacaatt gcattaggat tttttttata gaaattgaaa
    10261 gaatccacta tagactgacc catagctatt ccatcttcta caacttctac atatgattca
    10321 aatcctttac atatacttct atctataaag tacgctactg ctagagggtc atttatcaca
    10381 cagccaatta ttccctcctg ttcccaatgg aaatcaatat aaaatctagt tatttcagtt
    10441 atatactttg ccatcttctt atcaagtcta tttataaact caataatatt aggagtaagt
    10501 acaatttttc tagttacatc taaacctacc atgtggattt ttttagataa attcttgtaa
    10561 acataatctg ctccatgtgg gtctacccaa taattaaact ctgctactgg agagcaattt
    10621 ccatgaatcc taaatgctcc tcccatagat acaaactcat cgagattttc aaatgctttc
    10681 ttatctttaa taagtgcttt agctatattt gtaagtggtg caagtgctat tattgatact
    10741 ttttcatgat tatataaagt atttattata aaatccactg ctccattttt tgctttagct
    10801 cctacaacct tttgataaaa gttttctcca ataccatctt ctccatgtgt atcttgagct
    10861 gttacaagtt ttctttttag tggtgcttct tctcctatat atactggaat atttagtgaa
    10921 gaacacattt gaagtgtttt tagtgcattt tctgcaccta tatttgctgg aacatttcca
    10981 caacatgtgg taattccaat tacttctagc tctggtgagt ttaaagccag aagaattgcc
    11041 aaagaatcat caattcctgg gtcacaatca attattactt ttctcttttc cattttttat
    11101 cctccttgat ttgtggtcga ggagaactac acatcttttt tccactttca aaaaggtgtg
    11161 tctaagggta ttaattatat actgccacta tataattcct tagtttttta tacttggagt
    11221 tctcgaacaa gtacagatgt aaaatcatat ttttaggcta cttactatag actcttaaaa
    11281 actatagact gttaaaaaat ttttaaacat ctgatttaat agctataaaa taaattttat
    11341 agcataaaag aatttattat attttaatgt atcttattaa agtttattta gaattatgaa
    11401 ccaactttaa taagatgtgg cgcatttaaa ccgattatta ttatacaata atatcttaaa
    11461 tattacaatt aataacatta atttattatc cataaaaata tattaactta tattatttaa
    11521 taatttattg acagtattaa aattaaatta tacaataaca gtgtaaatta acttaacacc
    11581 gttaagcaaa gaggtgatta tatgagtatc aaagaaagac gtaaaaatga aaaagaagaa
    11641 atgaagaaaa agattatgga tgctagcatc gaaattataa accaacatgg atatgaaaat
    11701 ttatcaataa gaaaaattgc tacaaaaata gaatattctc caactacaat ttatctttac
    11761 tacaaagaca aagcagagat tatcagcgat atgaccaata aactttataa cacagtagaa
    11821 agtaatgcca ttgacattat gaataattgc tcatcactac caatagataa acaaatcata
    11881 gaaattatga ctagctttat aaaaactctt tctagtgaac cagagatggc aaaatctatc
    11941 atgtatagta gaatgaatat tatatttgca tctgaaaata caaacaatac gcctagcaat
    12001 aatggtataa aaatgcttga taaattcctt tccattggaa ttgaacaagg aatattcaaa
    12061 aaaaatatag ataaaagctc atggatgctt ataagtgcat tgttaggatt cgttttatgt
    12121 gttgttgaaa ataaactata ttctttacat aatttttctc aacttataga aaatttctta
    12181 gatattttag tgggaggact ttacaatgaa aattcgcaac aaggctacta ataaaaagaa
    12241 aaaatatgta aaaatatcta ttgctctatt ctttgtattt atatgcatta ttattgtaat
    12301 tgtaagcaac ttaaagccag aaaacttggt agtaaaagat atagatatta ataatgttaa
    12361 aaatggcatt tatactggaa gtgctgataa taacttggta aaagctactg tgtctgttga
    12421 agttaataat ggtaaaatcc aaaatattaa tatcttaaaa cacgaccatc ttttaggtaa
    12481 acctgctgaa aaaattacaa caagtattat taaacaacag tctttagatg tggatgctat
    12541 aacttctgca acttatagca gtaatactat acgaaaagct gtagaaaatg ctttaagaaa
    12601 gggagaataa ttatgaatac tattattata tattcaagta aatatggttg tacaaaagac
    12661 tgtgcaaata tactaaaaaa taaactatca gataatgtca ctattgttga tattaataat
    12721 aataataata aaattgagtt atcaaaattt gataaaatta ttattggaag ttctatatat
    12781 gttggttcag tttcaaaaaa aatacaagtg ctatgtaatg ataatgtaga gttattaaac
    12841 aaaaaacaag ttggcatttt cctttgctgt ggcttttctg aacaagcaga taaatattta
    12901 aaatcaaatt ttccatcatc cttattagaa agtgcaaatg ctattggaat ttttggtagt
    12961 gaagctcgat tagaaaaaat gaaattttta gataaactta ttatgaaggc tgtttcaaaa
    13021 ggtaattatg acagttttag aatatcacag gataatatag ataatttttt aataaatctt
    13081 aatagctaaa ataaaactaa ttatttctat gataaattct tttatttata agtaatattg
    13141 ctcaaaatag tctttaaact ttatcaaaat tttatttttc ttagtgaaat ctaatgaaac
    13201 tagcacttaa tatatgcttt attaatcata acaaatatgt tttattaatc ataacaaaaa
    13261 gagagtgtct aatgaactaa aaaattcatt agacactctc tttttgtatg aaatcaaata
    13321 tatttttatc atttcaaaag tgaaaaatac acttgtctct atgtttggca cattctcttt
    13381 ttataatata atatctaatt taaaacctat ttcaaatatt gacatatact taaactatag
    13441 acttacaaaa tcaattcata ttagcttaaa atataatctt tgttattcaa attcctatac
    13501 acaaccatta tttactttga tactttaaaa catcttccct attttttatt aaattttata
    13561 ataatagtcc tattaacgca aatactataa aaagagttta actttatcca ttaaataaat
    13621 ttaaattaaa acatatagaa atggaaggag aacaatttat gataaaacta atcggtatat
    13681 tgatagttgt aattggattt atacttaaaa ttgacacatt atttactgta ttattagcag
    13741 gagtggcaac aggaattgtt gcaggattag attttaatca aatttttaca attttaggag
    13801 attcttttgt ctcaaacaga ggtgtatcat tattcatatt aacattgcca gtaatcggtg
    13861 tattagaaag atatggttta aaacaaagag ctgtttcttt aatagaaaaa ttaaaaagac
    13921 ttacaacagg aaaagtactt actatataca tgatagctag acaaatagct ggtgctctat
    13981 caataagaat gagtggacat cctcaatttg taagaccact tgttaatcct atggcacaag
    14041 ctgctggttt aagtaatagt gatgagctaa aagaatcgga tgaagaagcc ataaaggcat
    14101 tatctgctgc atcagaaaac tatggaaatt tttatggtca aaacttattt gcaggtagta
    14161 gtggagtatt acttatagca tctactctga ctcaatttgg atacaatgta actggactta
    14221 atattgtaaa ggctagtact attatggcag taatagcact tgtagtggct acaatccagt
    14281 ttaccttata tgataaaaaa ttaaacaaaa gtcataaaaa atagttttat ttaggaggaa
    14341 taaaaatgca aaattttata aacatatcat tagaaatctt ttacgcacta atgggatttt
    14401 taatgattgt tatagcatat aagtctttta ctaccataaa taacaataag aaatatggta
    14461 catcattatt ttggatactt atatcactgc cattcatatt tggtagattg attccagcca
    14521 atataatagg aataatatta atattatcta gtttattaac actttctaaa caagttgtat
    14581 ttgcaaagta tgaagaacca gatgaaaatt ttggaaaaga acaagcagac aaacttaaaa
    14641 ataaaatatt tataccatca ttaatattag catttgctgc agtagtagta gctatgagcc
    14701 tttctaattt tgataattct tctcaatttg caataggtgt gggttcaata attgcattaa
    14761 tatcagccct tataataact aaggcaaaat ctgctacatc agttcaagat ggctcaagat
    14821 tacttcaaca aatgggacct gctagtatgt taccacaact tttagttgca ctgggagctt
    14881 tatttactca agccggagtc ggtgaagtta tttcaaccat gatatctggt gtagtccctg
    14941 ctgatagcag attatttggt gttatagctt atgtattagg tatggttata tttaccatga
    15001 taatgggaaa tgcatttgcc gcattttcag tcataacggc aggaattggt attccttttg
    15061 tattgtctca aggtggaaat cctgctataa ttggagcatt agcattaaca gcaggatatt
    15121 gtggaactct acttactcca atggctgcta attttaatat agttccagca gccttgctag
    15181 aatgtaaaaa tgattatatt gttataaaat atcaagctcc agttgctttg gtattaatta
    15241 tagcccacat attagtaatg tactttttag gattttaata taattaggag gtaaaataat
    15301 gaaaattttg ttaacaggat ttgacccatt tggtggagaa ccaataaacc cagctcaaga
    15361 agcagttgaa agggtcaata ataatataaa cggtgcagaa atcataaaga taactatacc
    15421 aacagttatg acaaaatctg ttgaagctat agataaagct attcaagagc acaatccaga
    15481 tatagtaata tcagttggac aagctggagg tagatttgac attacacctg agagagttgc
    15541 tataaatata gatgatttta gaataaaaga taatgagggt aaccaggtta tagatactat
    15601 tataaaagaa gatggtgaac ctgcatattt ttcaaaattg cctgtaaaag ctatggtaaa
    15661 acatatgaat gaaaataaaa ttccagctag tgtttcaaac actgcaggaa catttgtttg
    15721 caatcatgtg atgtatggaa ttctttatat gatagacaag aaatatccta atataagggg
    15781 tggatttata cacatcccat atacaacttc acaagtaata gataaaaaaa atacaccatt
    15841 catgtcttta gaagaaatag taaaaggctt agaattagct atagaagctt gtattatata
    15901 taaagaagat gtaaaagaaa ttggtggtga aatttcataa taaatttttt agtattttta
    15961 taaattaaaa atactaacta ttaatttaaa tatagactgt gagtagatta ttcaaacaat
    16021 tttactcaca gtctttttat ggtatctaca gatacaaaat taaggtctat tcctctctcc
    16081 ccactcacac attgcatcta aaattggaat cagagatttt cccctttctg atagactata
    16141 ttctacctta ggaggtattt gaggatattc agtacgaata atcaagttat ctgcttctaa
    16201 ttcttttaat gataaactca aagttttata ggagatagta tttatataac gttttaatgc
    16261 attatatctt acaacttcaa attctacaag acagtaaaga attatcatct tatatttacc
    16321 actaatcagt gaaagtgtat aactaaatcc tgtttcactt aaatctgtat ttgatataca
    16381 gtctatactc atatattaca ctctcctttt ggttagtatt gaacaaaaat gtgcgtactt
    16441 gtttttagaa taatttataa taaaattata gtgtaagaat aattgaaagt caattttata
    16501 ataggaggtg tatttactaa aaaaaaagtt attttaaata ggattctaag attagacatt
    16561 tctatataaa ttgataatat tcatgaaaat cctattttat aaaaaataat atctcttaga
    16621 aaatctatta aataaaattc attggaggaa atttataatg aaagttttat tgataaacgg
    16681 tagcccaaac caatatggat gtacttatac agcactaaat gagattacta aagtattgag
    16741 taaacacgat attaaaacag aaatactgta tttaggtaaa gaaacaatcc caggatgtat
    16801 tagttgcgca tcctgttttg aaactggaaa atgtattcga aatgataaag ttaataaatt
    16861 gattgaagat ctggataata ttgatggtat tattattggt tctcctgttt acttttctag
    16921 tgcaactggt caattaactt cttttcttga ccgtctattt ttcatagctg gaagtcgcat
    16981 ggctacaaaa ttaggtgctt cagttgtgtc atgtagacgt ggtggtgcaa gtgcaacatt
    17041 tgaccaacta aataaatatt tttcaatcag caatatgcct attgtatcat cacagtattg
    17101 gaaccaggta catggcttta ctccagagga tgttatgaag gatgaagaag gattacagac
    17161 tatgcgaact ctaggagaaa acatggcatg gcttcttaag tgtatatcag caggtaaaaa
    17221 agctggaatt aaagaaccac aatatgaaga aacaattatg actaatttta taaaataaat
    17281 aaaaaatgta ctaatattaa ttaaaacaaa acactaattt ataaataaaa taagcataaa
    17341 tgtaggataa aaagcactaa aacagaggta ttgaatttta tatcaaacct ctgttttatt
    17401 attacattaa taaccaaacc atgtataaca tcatatattt ctaaataaat tataatatta
    17461 tattctaatg ttattgaaat tacaataact gaatttctgc tcataaattt aaatattcta
    17521 caaatctcat ctaaataaca attttaatag acctaaaaca atcctcatac tgttcatttt
    17581 gtattaaaaa tatcacttac aatcaaaaac catttattaa gtatattcct aagatataca
    17641 atatatatac atggattgga tagtataaat aaaataaata cttcatactc ttcccttttt
    17701 ctccattgta aagtaacatt aaaggtagag aagcaatcat catccattgg taattttgta
    17761 aaatagaatt ttttaaacta taatctccat ttgacattgt tgtaaatata aatatacaca
    17821 ttaaaacata acaaatactc aaactgaact ttttacctct acacaaataa aaaataatcc
    17881 caagtataat ccaaattggt ccaccttcta ctaaaaatgg tactggtacc aaaatcataa
    17941 ataaagcaat aactctgtta gtgactttaa aaagtaaagc tactgtaaat attcctaaaa
    18001 ttataggaat gattatcatc aataatccta taataaaata tttaatttct ttctcttttc
    18061 taaatttctt tatgaactct attgcttgta aataaatcgc tattaaaaat aatgttgaaa
    18121 aaatgttatt tataattata gctccttctg gatgtgaaaa tacattatta attatttgat
    18181 ttcctatagc cataataaca gaccaaatat acaatctact tatatatttt tttctgttac
    18241 tagtgtgata aaatccttca acagccatga atataaacag tggtgctgat attctgccta
    18301 cccaatgaaa ccaaattggt atttgcattg tttgtggcat aaatgctgct atatggtcaa
    18361 atgtcataaa tattaatgct aaaattttaa tagtaaaccc acttatacct tttttaaaaa
    18421 aatccatatc atatctccta attttgtttt atctctataa taatttttgt tcctattcca
    18481 atttcactac ttacataaat tttaccttta tgaatctcta ttatttcttt agaaatagcc
    18541 ataccaagac ctgaaccttt atgcatctca cctgtattag tacctctata atatttttta
    18601 aaaatatgtt tcaaatcact tttgcttatt ccaattccat tatcttttat tataatttct
    18661 atattatctt tttttacaat ttctacactt atcaaagttc cttcgctatt atgaactatt
    18721 gaattaaata taagattggt tatagccctt ctgaataaga ttgaatctac atatacttca
    18781 attaaatctt cattactttc aaattcaata ttcctatttt tatatctatt atcatttaaa
    18841 atatcaatta ttatatctct gactaaactg actaaattta tttttttctt gtccagaact
    18901 atagtattat tttttaatcg agtagataaa tttaaatcat caactaaatc ttttatatac
    18961 ttagacttat tatatataat ttctgtatac tcttgtattt catcttcttc aaactcataa
    19021 tctttgtcat taattatctc tgcataccct tgtatagatg ctagaggtgt ctttatatca
    19081 tgtgttatat ttgccagcca ttcctctctc aactcttcat tttcttttct ctcaacttca
    19141 tttactctta aagtatcagc taacatattt atatttttaa aaacttcttc atatatacct
    19201 ctgtccttaa gatataaact ataatttcca ttagccatag tctcaatact ccatagtacg
    19261 cttgaaattg gttttgtaag ttttctacta aataaatatc ctacacctaa agctaccacg
    19321 ctatcaatta ctagtgttat aatgataact ttatttaaag tttttttaat gttattttga
    19381 gaataggtta aaattattct tgatatatct ctactaggta tacctactat tatgtttaaa
    19441 tgttttttgt ttaaatattt ttctagtaca aaattaacat actttgtttc tatatacttg
    19501 taattattca ccatttgaaa gggtgtatat ttttttggag tatcctttgg cacatttact
    19561 ccataaactt cctctcctaa atcatttaaa acctgtatcc aggaatttga tttttctaat
    19621 ttttcagctc caatcttaga tagtttaaat tctccatctt tttcatataa atctttttca
    19681 aaagaacgtg caaattcttc aggattattt ccagaatcta caactttaaa aaaactatta
    19741 gttgaaatca catacaatat agatatgata tttataatta ctactgatat agctacaaac
    19801 acaattgtaa atataaaatt tctagtaatc ttccacttca tattctaatc ttcctttact
    19861 gctaatttat atccaagacc ttttattgtc agaatatatt caggctttga aggattatcc
    19921 tctaattttt ccctaatttt tcttatatga accattatag tattgtcaaa tccaacataa
    19981 tcttctcccc acactttatc ccatagtttt tctttactta taatttgatt ttgattatgt
    20041 gcaaataaag ataggatttt tagttccttt gcagacagtc ctatagattt tccatctttt
    20101 ataagttctg ccctactttc atttaatata tatgggccaa atgatataat tttttcttca
    20161 ttattattta gatttttact ttcgttttga acgtcactaa aataacttaa tcttctcaaa
    20221 tgcgctttaa ctctaaaagc cacttcctta gggctaaaag gttttgtaac ataatcatct
    20281 cctccaatcg ctagtccaag taacttatct aattcttcgg ttttagctga taaaaatatt
    20341 attggagaat tggaggtttt tcttatttct ttacaaatat cataaccttc gccatctggt
    20401 aacataatat ccaatacaat caaatcagga ttaatacttt taaataattc taatccttct
    20461 tttttagttt ttgcagtata tatattatta aggccttctt tttttaggac agtttctaaa
    20521 agcttcaata tttctacttc atcatctatt attaaaacac gattttccat aaacaacctc
    20581 ctgtaataat ttacatatat atta
//
LOCUS       DAEQAF010000069        20480 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.071, whole genome shotgun sequence.
ACCESSION   DAEQAF010000069 DAEQAF010000000
VERSION     DAEQAF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20480
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.071"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            291..845
                     /gene="tcdR"
                     /locus_tag="KRN00_002596"
     CDS             291..845
                     /gene="tcdR"
                     /locus_tag="KRN00_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBH1828455.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            1163..8263
                     /gene="tcdB"
                     /locus_tag="KRN00_002597"
                     /gene_synonym="toxB"
     CDS             1163..8263
                     /gene="tcdB"
                     /locus_tag="KRN00_002597"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBH1828456.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETEEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGIASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKVMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKLSFGYYSNNLKDVKVITKDNVNILTGCYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGSTNTSDSLMSFLESMNIKSIFVNLLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVVVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFEDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDDKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            8385..8885
                     /gene="tcdE"
                     /locus_tag="KRN00_002598"
     CDS             8385..8885
                     /gene="tcdE"
                     /locus_tag="KRN00_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBH1828457.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAVLLDAMTDEM
                     NAKDEK"
     gene            8964..9125
                     /locus_tag="KRN00_002599"
     CDS             8964..9125
                     /locus_tag="KRN00_002599"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828458.1"
                     /translation="MKLIMKTREQMPRDTQVLNTYNFEASVHYYMDDKVVYQTLVHKD
                     GAWSVGKIY"
     gene            9214..9396
                     /locus_tag="KRN00_002600"
     CDS             9214..9396
                     /locus_tag="KRN00_002600"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828459.1"
                     /translation="MRDEGQNDRENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            9613..17745
                     /gene="tcdA"
                     /locus_tag="KRN00_002601"
                     /gene_synonym="toxA"
     CDS             9613..17745
                     /gene="tcdA"
                     /locus_tag="KRN00_002601"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBH1828460.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSGSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(18080..18778)
                     /gene="tcdC"
                     /locus_tag="KRN00_002602"
     CDS             complement(18080..18778)
                     /gene="tcdC"
                     /locus_tag="KRN00_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBH1828461.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPACSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            19204..19449
                     /locus_tag="KRN00_002603"
     CDS             19204..19449
                     /locus_tag="KRN00_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBH1828462.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(19667..19936)
                     /locus_tag="KRN00_002604"
     CDS             complement(19667..19936)
                     /locus_tag="KRN00_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1828463.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
BASE COUNT         8117 a         2299 c         3101 g         6963 t
ORIGIN      
        1 gaaaaaagaa atataaatat aaaaatatgt cgtatagatt ttttctattt tactttaata
       61 aaatgatttg tttttacaat actttattaa tataaagttt attgctaaaa tactttattt
      121 attagaaaaa gattactaat taattattaa aattaatgta ttcataatgc atattttcat
      181 ataaaattta atttatttgc cgattatata attataatga ctgatttaat tccgatgttg
      241 tcaaaatttt caaataaatc atcattataa atataagaga ggatgatttt atgcaaaagt
      301 ctttttatga attaattgtt ttagcaagaa ataactcagt agatgatttg caagaaattt
      361 tatttatgtt taagccatta gtaaaaaaac ttagtagagt tttacattat gaagagggag
      421 aaacagattt aataatattt tttattgaat taataaaaaa tattaaatta agtagctttt
      481 cagaaaaaag cgatgctatt atagtcaaat atattcataa atcattactg aataagactt
      541 ttgagttgtc tagaagatat tctaaaatga agtttaattt tgtagaattt gatgaaaata
      601 tcttaaatat gaaaaataat tatcaaagta agtctgtttt tgaggaagat atttgttttt
      661 tcgaatatat tttgaaagaa ttatctggta ttcaaagaaa agttattttt tataaatatt
      721 taaaaggata ttctgataga gaaatatcag tgaaattaaa aatatctaga caagctgtta
      781 ataaggctaa aaatagagca tttaaaaaaa taaaaaaaga ctatgaaaat tattttaact
      841 tgtaattaat gagcttaaag aaatatttac aatagaaatc aaattttaga attaacttta
      901 ttgtaaaatt aataacttaa tctaagaata tcttaatttt tatattttat atagaacaaa
      961 gtttacatat ttatttcaga caacgtcttt attcaatcga agagcaaatt aatcaactga
     1021 gtgtcttcaa tttaaaatgt taggaagtga atgtatatga aaacctaagt agatattagt
     1081 atattttata aatagaaagg aggatatata aaagagtttt agcatttaga tgtaaaaata
     1141 ttatagtaaa ggagaaaatt ttatgagttt agttaataga aaacagttag aaaaaatggc
     1201 aaatgtaaga tttcgtactc aagaagatga atatgttgca atattggatg ctttagaaga
     1261 atatcataat atgtcagaga atactgtagt cgaaaaatat ttaaaattaa aagatataaa
     1321 tagtttaaca gatatttata tagatacata taaaaaatct ggtagaaata aagccttaaa
     1381 aaaatttaag gaatatctag ttacagaagt attagagcta aagaataata atttaactcc
     1441 agttgagaaa aatttacatt ttgtttggat tggaggtcaa ataaatgaca ctgctattaa
     1501 ttatataaat caatggaaag atgtaaatag tgattataat gttaatgttt tttatgatag
     1561 taatgcattt ttgataaaca cattgaaaaa aactgtagta gaatcagcaa taaatgatac
     1621 acttgaatca tttagagaaa acttaaatga ccctagattt gactataata aattcttcag
     1681 aaaacgtatg gaaataattt atgataaaca gaaaaatttc ataaactact ataaagctca
     1741 aagagaagaa aatcctgaac ttataattga tgatattgta aagacatatc tttcaaatga
     1801 gtattcaaag gagatagatg aacttaatac ctatattgaa gaatccttaa ataaaattac
     1861 acagaatagt ggaaatgatg ttagaaactt tgaagaattt aaaaatggag agtcattcaa
     1921 cttatatgaa caagagttgg tagaaaggtg gaatttagct gctgcttctg acatattaag
     1981 aatatctgca ttaaaagaaa ttggtggtat gtatttagat gttgatatgt taccaggaat
     2041 acaaccagac ttatttgagt ctatagagaa acctagttca gtaacagtgg atttttggga
     2101 aatgacaaag ttagaagcta taatgaaata caaagaatat ataccagaat atacctcaga
     2161 acattttgac atgttagatg aagaagttca aagtagtttt gaatctgttc tagcttctaa
     2221 gtcagataaa tcagaaatat tctcatcact tggtgatatg gaggcatcac cactagaagt
     2281 taaaattgca tttaatagta agggtattat aaatcaaggg ctaatttctg tgaaagactc
     2341 atattgtagc aatttaatag taaaacaaat cgagaataga tataaaatat tgaataatag
     2401 tttaaatcca gctattagcg aggataatga ttttaatact acaacgaata cctttattga
     2461 tagtataatg gctgaagcta atgcagataa tggtagattt atgatggaac taggaaagta
     2521 tttaagagtt ggtttcttcc cagatgttaa aactactatt aacttaagtg gccctgaagc
     2581 atatgcggca gcttatcaag atttattaat gtttaaagaa ggcagtatga atatccattt
     2641 gatagaagct gatttaagaa actttgaaat ctctaaaact aatatttctc aatcaactga
     2701 acaagaaatg gctagcttat ggtcatttga cgatgcaaga gctaaagctc aatttgaaga
     2761 atataaaagg aattattttg aaggttctct tggtgaagat gataatcttg atttttctca
     2821 aaatatagta gttgacaagg agtatctttt agaaaaaata tcttcattag caagaagttc
     2881 agagagagga tatatacact atattgttca gttacaagga gataaaatta gttatgaagc
     2941 agcatgtaac ttatttgcaa agactcctta tgatagtgta ctgtttcaga aaaatataga
     3001 agattcagaa attgcatatt attataatcc tggagatggt gaaatacaag aaatagacaa
     3061 gtataaaatt ccaagtataa tttctgatag acctaagatt aaattaacat ttattggtca
     3121 tggtaaagat gaatttaata ctgatatatt tgcaggtttt gatgtagatt cattatccac
     3181 agaaatagaa gcagcaatag atttagctaa agaggatatt tctcctaagt caatagaaat
     3241 aaatttatta ggatgtaata tgtttagcta ctctatcaac gtagaggaga cttatcctgg
     3301 aaaattatta cttaaagtta aagataaaat atcagaatta atgccatcta taagtcaaga
     3361 ctctattata gtaagtgcaa atcaatatga agttagaata aatagtgaag gaagaagaga
     3421 attattggat cattctggtg aatggataaa taaagaagaa agtattataa aggatatttc
     3481 atcaaaagaa tatatatcat ttaatcctaa agaaaataaa attacagtaa aatctaaaaa
     3541 tttacctgaa ttatctacat tattacaaga aattagaaat aattctaatt caagtgatat
     3601 tgaactagaa gaaaaagtaa tgttaacaga atgtgagata aatgttattt caaatataga
     3661 tacgcaaatt gttgaggaaa ggattgaaga agctaagaat ttaacttctg actctattaa
     3721 ttatataaaa gatgaattta aactaataga atctatttct gatgcactat gtgacttaaa
     3781 acaacagaat gaattagaag attctcattt tatatctttt gaggacatat cagagactga
     3841 agagggattt agtataagat ttattaataa agaaactgga gaatctatat ttgtagaaac
     3901 tgaaaaaaca atattctctg aatatgctaa tcatataact gaagagattt ctaagataaa
     3961 aggtactata tttgatactg taaatggtaa gttagtaaaa aaagtaaatt tagatactac
     4021 acacgaagta aatactttaa atgctgcatt ttttatacaa tcattaatag aatataatag
     4081 ttctaaagaa tctcttagta atttaagtgt agcaatgaaa gttcaagttt acgctcaatt
     4141 atttagtact ggtttaaata ctattacaga tgcagccaaa gttgttgaat tagtatcaac
     4201 tgcattagat gaaactatag acttacttcc tacattatct gaaggattac ctataattgc
     4261 aactattata gatggtgtaa gtttaggtgc agcaatcaaa gagctaagtg aaacgagtga
     4321 cccattatta agacaagaaa tagaagctaa gataggtata atggcagtaa atttaacaac
     4381 agctacaact gcaatcatta cttcatcttt ggggatagct agtggattta gtatactttt
     4441 agttccttta gcaggaattt cagcaggtat accaagctta gtaaacaatg aacttgtact
     4501 tcgagataag gcaacaaagg ttgtagatta ttttaaacat gtttcattag ttgaaactga
     4561 aggagtattt actttattag atgataaagt aatgatgcca caagatgatt tagtgatatc
     4621 agaaatagat tttaataata attcaatagt tttaggtaaa tgtgaaatct ggagaatgga
     4681 aggtggttca ggtcatactg taactgatga tatagatcac ttcttttcag caccatcaat
     4741 aacatataga gagccacact tatctatata tgacgtattg gaagtacaaa aagaagaact
     4801 tgatttgtca aaagatttaa tggtattacc taatgctcca aatagagtat ttgcttggga
     4861 aacaggatgg acaccaggtt taagaagctt agaaaatgat ggcacaaaac tgttagaccg
     4921 tataagagat aactatgaag gtgagtttta ttggagatat tttgctttta tagctgatgc
     4981 tttaataaca acattaaaac caagatatga agatactaat ataagaataa atttagatag
     5041 taatactaga agttttatag ttccaataat aactacagaa tatataagag aaaaattatc
     5101 atattctttc tatggttcag gaggaactta tgcattgtct ctttctcaat ataatatggg
     5161 tataaatata gaattaagtg aaagtgatgt ttggattata gatgttgata atgttgtgag
     5221 agatgtaact atagaatctg ataaaattaa aaaaggtgat ttaatagaag gtattttatc
     5281 tacactaagt attgaagaga ataaaattat cttaaatagc catgagatta atttttctgg
     5341 tgaggtaaat ggaagtaatg gatttgtttc tttaacattt tcaattttag aaggaataaa
     5401 tgcaattata gaagttgatt tattatctaa atcatataaa ttacttattt ctggcgaatt
     5461 aaaaatattg atgttaaatt caaatcatat tcaacagaaa atagattata taggattcaa
     5521 tagcgaatta cagaaaaata taccatatag ctttgtagat agtgaaggaa aagagaatgg
     5581 ttttattaat ggttcaacaa aagaaggttt atttgtatct gaattacctg atgtagttct
     5641 tataagtaag gtttatatgg atgatagtaa gctttcattt ggatattata gtaataattt
     5701 gaaagatgtc aaagttataa ctaaagataa tgttaatata ttaacaggtt gttatcttaa
     5761 ggatgatata aaaatctctc tttctttgac tctacaagat gaaaaaacta taaagttaaa
     5821 tagtgtgcat ttagatgaaa gtggagtagc tgagattttg aagttcatga atagaaaagg
     5881 tagtacaaat acttcagatt ctttaatgag ctttttagaa agtatgaata taaaaagtat
     5941 tttcgttaat ttattacaat ctaatattaa gtttatatta gatgctaatt ttataataag
     6001 tggtactact tctattggcc aatttgagtt tatttgtgat gaaaatgata atatacaacc
     6061 atatttcatt aagtttaata cactagaaac taattatact ttatatgtag gaaatagaca
     6121 aaatatgata gtggaaccaa attatgattt agatgattct ggagatatat cttcaactgt
     6181 tatcaatttc tctcaaaagt atctttatgg aatagacagt tgtgttaata aagttgtaat
     6241 ttcaccaaat atttatacag atgaaataaa tataacgcct gtatatgaaa caaataatac
     6301 ttatccagaa gttgttgtat tagatgcaaa ttatataaac gaaaaaataa atgttaatat
     6361 caatgatcta tctatacgat atgtatggag taatgatggt aatgatttta ttcttatgtc
     6421 aactagtgaa gaaaataagg tgtcacaagt taaaataaga ttcgttaatg tttttaaaga
     6481 taagactttg gcaaataagc tatcttttaa ctttagtgat aaacaagatg tacctgtaag
     6541 tgaaataatc ttatcattta caccttcata ttatgaggat ggattgattg gctatgattt
     6601 gggtctagtt tctttatata atgagaaatt ttatattaat aactttggaa tgatggtatc
     6661 tggattaata tatattaatg attcattata ttattttaaa ccaccagtaa ataatttgat
     6721 aactggattt gtgactgtag gcgatgataa atactacttt aatccaatta atggtggagc
     6781 tgcttcaatt ggagagacaa taattgatga caaaaattat tatttcaacc aaagtggagt
     6841 gttacaaaca ggtgtattta gtacagaaga tggatttaaa tattttgccc cagctaatac
     6901 acttgatgaa aacctagaag gagaagcaat tgattttact ggaaaattaa ttattgacga
     6961 aaatatttat tattttgaag ataattatag aggagctgta gaatggaaag aattagatgg
     7021 tgaaatgcac tattttagcc cagaaacagg taaagctttt aaaggtctaa atcaaatagg
     7081 tgatgataaa tactatttca attctgatgg agttatgcaa aaaggatttg ttagtataaa
     7141 tgataataaa cactattttg atgattctgg tgttatgaaa gtaggttaca ctgaaataga
     7201 tggcaagcat ttctactttg ctgaaaacgg agaaatgcaa ataggagtat ttaatacaga
     7261 agatggattt aaatattttg ctcatcataa tgaagattta ggaaatgaag aaggtgaaga
     7321 aatctcatat tctggtatat taaatttcaa taataaaatt tactattttg atgattcatt
     7381 tacagctgta gttggatgga aagatttaga ggatggttca aagtattatt ttgatgaaga
     7441 tacagcagaa gcatatatag gtttgtcatt aataaatgat ggtcaatatt attttaatga
     7501 tgatggaatt atgcaagttg gatttgtcac tataaatgat aaagtcttct acttctctga
     7561 ctctggaatt atagaatctg gagtacaaaa catagatgac aattatttct atatagatga
     7621 taatggtata gttcaaattg gtgtatttga tacttcagat ggatataaat attttgcacc
     7681 tgctaatact gtaaatgata atatttacgg acaagcagtt gaatatagtg gcttagttag
     7741 agttggtgaa gatgtatatt attttggaga aacatataca attgagactg gatggatata
     7801 tgatatggaa aatgaaagtg ataaatatta tttcaatcca gaaactaaaa aagcatgcaa
     7861 aggtattaat ttaattgatg atataaaata ttattttgat gagaagggca taatgagaac
     7921 gggtcttata tcatttgaaa ataataatta ttactttaat gagaatggtg aaatgcaatt
     7981 tggttatata aatatagaag ataagatgtt ctattttggt gaagatggtg tcatgcagat
     8041 tggagtattt aatacaccag atggatttaa atactttgca catcaaaata ctttggatga
     8101 gaattttgag ggagaatcaa taaactatac tggttggtta gatttagatg aaaagagata
     8161 ttattttaca gatgaatata ttgcagcaac tggttcagtt attattgatg gtgaggagta
     8221 ttattttgat cctgatacag ctcaattagt gattagtgaa tagataaaaa tatgttaaat
     8281 atatcctctt atacttaaat atataaaaat aaacaaaatg atacactaca taaagtgttc
     8341 tatctaatat gaagatttac caataaaaag gtggactatg atgaatgcac agtagttcac
     8401 ctttttatat ttctaatggt aacaaaatat ttttttatat aaacctagga ggcgttatga
     8461 atatgacaat atctttttta tcagagcata tatttataaa gttagtaatt ttaactatat
     8521 catttgatac attattagga tgtttaagtg caataaaaag tcgtaaattt aattctagtt
     8581 ttggaataga tggaggaatc agaaaagtag caatgatagc atgtatattt tttttatcag
     8641 tagttgacat tcttacaaag tttaactttt tatttatgtt accacaagat tgtatcaatt
     8701 ttttaagact aaaacatctt ggaatatctg aatttttctc tattttattt attttatatg
     8761 aaagtgtaag tatattaaaa aatatgtgct tatgtggatt accagtacct aagagattaa
     8821 aggaaaaaat agcagtttta ctagatgcaa tgacagatga aatgaatgct aaggatgaaa
     8881 agtaagtaat ggtagatata ataaagatat taacaaataa aaagtgttat ccaaataaga
     8941 atagctgaaa gttatcataa ttcatgaaac taataatgaa aacgagggag cagatgccaa
     9001 gagacacaca agtattaaat acatataatt tcgaagcaag tgttcattac tatatggatg
     9061 acaaggtagt atatcaaaca ttggttcaca aagatggtgc atggtcagtt ggtaaaatct
     9121 attaagctac attagttaca gatatcacaa actataatag ttaaacatag aaatatgtgt
     9181 aaattgtgat ggaaattatt caaaaacaca aaaatacgtg atgaaggaca aaatgataga
     9241 gaaaataagt atcaaacctt aataaatgat ttaattgata gtttaaaagt tataggaaaa
     9301 atatataaag aaataaaaac attaaaaaaa tataagatat gtttacaaat tactatcaga
     9361 caatctcctt atctaataga agagtcaatt aactaattga gtatctttaa attgaaatgt
     9421 taggaagtga tttaaatatg aaaacttaaa ttataaaaaa tcaatattaa tttattttta
     9481 aaaaatagaa aggagtgtat aagatttatt ttcaaagttt aaaaacaaga aaatcaattt
     9541 aaatttcaga aggaataaat gtggttatag aagtggattt attatcaaaa ataataatac
     9601 taggaggttt ttatgtcttt aatatctaaa gaagagttaa taaaactcgc atatagcatt
     9661 agaccaagag aaaatgagta taaaactata ctaactaatt tagacgaata taataagtta
     9721 actacaaaca ataatgaaaa taaatattta caattaaaaa aactaaatga atcaattgat
     9781 gtttttatga ataaatataa aacttcaagc agaaatagag cactctctaa tctaaaaaaa
     9841 gatatattaa aagaagtaat tcttattaaa aattccaata caagccctgt agaaaaaaat
     9901 ttacattttg tatggatagg tggagaagtc agtgatattg ctcttgaata cataaaacaa
     9961 tgggctgata ttaatgcaga atataatatt aaactgtggt atgatagtga agcattctta
    10021 gtcaatacac taaaaaaggc tatagttgaa tcttctacca ctgaagcatt acagctacta
    10081 gaggaagaga ttcaaaatcc tcaatttgat aatatgaaat tttacaaaaa aaggatggaa
    10141 tttatatatg atagacaaaa aaggtttata aattattata aatctcaaat caataaacct
    10201 acagtaccta caatagatga tattataaag tctcatctag tatctgaata taatagagat
    10261 gaaactgtat tagaatcata tagaacaaat tctttgagaa aaataaatag taatcatggg
    10321 atagatatca gggctaatag tttgtttaca gaacaagagt tattaaatat ttatagtcag
    10381 gagttgttaa atcgtggaaa tttagctgca gcatctgaca tagtaagatt attagcccta
    10441 aaaaattttg gcggagtata tttagatgtt gatatgcttc caggtattca ctctgattta
    10501 tttaaaacaa tatctagacc tagctctatt ggactagacc gttgggaaat gataaaatta
    10561 gaggctatta tgaagtataa aaaatatata aataattata catcagaaaa ctttgataaa
    10621 cttgatcaac aattaaaaga taattttaaa ctcattatag aaagtaaaag tgaaaaatct
    10681 gagatatttt ctaaattaga aaatttaaat gtatctgatc ttgaaattaa aatagctttc
    10741 gctttaggca gtgttataaa tcaagccttg atatcaaaac aaggttcata tcttactaac
    10801 ctagtaatag aacaagtaaa aaatagatat caatttttaa accaacacct taacccagcc
    10861 atagagtctg ataataactt cacagatact actaaaattt ttcatgattc attatttaat
    10921 tcagctaccg cagaaaactc tatgttttta acaaaaatag caccatactt acaagtaggt
    10981 tttatgccag aagctcgctc cacaataagt ttaagtggtc caggagctta tgcatcagct
    11041 tactatgatt tcataaattt acaagaaaat actatagaaa aaactttaaa agcatcagat
    11101 ttaatagaat ttaaattccc agaaaataat ctatctcaat tgacagaaca agaaataaat
    11161 agtctatgga gctttgatca agcaagtgca aaatatcaat ttgagaaata tgtaagagat
    11221 tatactggtg gatctctttc tgaagacaat ggggtagact ttaataaaaa tactgccctc
    11281 gacaaaaact atttattaaa taataaaatt ccatcaaaca atgtagaaga agctggaagt
    11341 aaaaattatg ttcattatat catacagtta caaggagatg atataagtta tgaagcaaca
    11401 tgcaatttat tttctaaaaa tcctaaaaat agtattatta tacaacgaaa tatgaatgaa
    11461 agtgcaaaaa gctacttttt aagtgatgat ggagaatcta ttttagaatt aaataaatat
    11521 aggatacctg aaagattaaa aaataaggaa aaagtaaaag taacctttat tggacatggt
    11581 aaagatgaat tcaacacaag cgaatttgct agattaagtg tagattcact ttccaatgag
    11641 ataagttcat ttttagatac cataaaatta gatatatcac ctaaaaatgt agaagtaaac
    11701 ttacttggat gtaatatgtt tagttatgat tttaatgttg aagaaactta tcctgggaag
    11761 ttgctattaa gtattatgga caaaattact tccactttac ctgatgtaaa taaaaattct
    11821 attactatag gagcaaatca atatgaagta agaattaata gtgagggaag aaaagaactt
    11881 ctggctcact caggtaaatg gataaataaa gaagaagcta ttatgagcga tttatctagt
    11941 aaagaataca ttttttttga ttctatagat aataagctaa aagcaaagtc caagaatatt
    12001 ccaggattag catcaatatc agaagatata aaaacattat tacttgatgc aagtgttagt
    12061 cctgatacaa aatttatttt aaataatctt aagcttaata ttgaatcttc tattggtgat
    12121 tacatttatt atgaaaaatt agagcctgtt aaaaatataa ttcacaattc tatagatgat
    12181 ttaatagatg agttcaatct acttgaaaat gtatctgatg aattatatga attaaaaaaa
    12241 ttaaataatc tagatgagaa gtatttaata tcttttgaag atatctcaaa aaataattca
    12301 acttactctg taagatttat taacaaaagt aatggtgagt cagtttatgt agaaacagaa
    12361 aaagaaattt tttcaaaata tagcgaacat attacaaaag aaataagtac tataaagaat
    12421 agtataatta cagatgttaa tggtaattta ttggataata tacagttaga tcatacttct
    12481 caagttaata cattaaacgc agcattcttt attcaatcat taatagatta tagtagcaat
    12541 aaagatgtac tgaatgattt aagtacctca gttaaggttc aactttatgc tcaactattt
    12601 agtacaggtt taaatactat atatgactct atccaattag taaatttaat atcaaatgca
    12661 gtaaatgata ctataaatgt actacctaca ataacagagg ggatacctat tgtatctact
    12721 atattagacg gaataaactt aggtgcagca attaaggaat tactagacga acatgaccca
    12781 ttactaaaaa aagaattaga agctaaggtg ggtgttttag caataaatat gtcattatct
    12841 atagctgcaa ctgtagcttc aattgttgga ataggtgctg aagttactat tttcttatta
    12901 cctatagctg gtatatctgc aggaatacct tcattagtta ataatgaatt aatattgcat
    12961 gataaggcaa cttcagtggt aaactatttt aatcatttgt ctgaatctaa aaaatatggc
    13021 cctcttaaaa cagaagatga taaaatttta gttcctattg atgatttagt aatatcagaa
    13081 atagatttta ataataattc gataaaacta ggaacatgta atatattagc aatggagggg
    13141 ggatcaggac acacagtgac tggtaatata gatcactttt tctcatctcc atctataagt
    13201 tctcatattc cttcattatc aatttattct gcaataggta tagaaacaga aaatctagat
    13261 ttttcaaaaa aaataatgat gttacctaat gctccttcaa gagtgttttg gtgggaaact
    13321 ggagcagttc caggtttaag atcattggaa aatgacggaa ctagattact tgattcaata
    13381 agagatttat acccaggtaa attttactgg agattctatg cttttttcga ttatgcaata
    13441 actacattaa aaccagttta tgaagacact aatattaaaa ttaaactaga taaagatact
    13501 agaaacttca taatgccaac tataactact aacgaaatta gaaacaaatt atcttattca
    13561 tttgatggag caggaggaac ttactcttta ttattatctt catatccaat atcaacgaat
    13621 ataaatttat ctaaagatga tttatggata tttaatattg ataatgaagt aagagaaata
    13681 tctatagaaa atggtactat taaaaaagga aagttaataa aagatgtttt aagtaaaatt
    13741 gatataaata aaaataaact tattataggc aatcaaacaa tagatttttc aggcgatata
    13801 gataataaag atagatatat attcttgact tgtgagttag atgataaaat tagtttaata
    13861 atagaaataa atcttgttgc aaaatcttat agtttgttat tgtctgggga taaaaattat
    13921 ttgatatcca atttatctaa tactattgag aaaatcaata ctttaggcct agatagtaaa
    13981 aatatagcgt acaattacac tgatgaatct aataataaat attttggagc tatatctaaa
    14041 acaagtcaaa aaagcataat acattataaa aaagacagta aaaatatatt agaattttat
    14101 aatgacagta cattagaatt taacagtaaa gattttattg ctgaagatat aaatgtattt
    14161 atgaaagatg atattaatac tataacagga aaatactatg ttgataataa tactgataaa
    14221 agtatagatt tctctatttc tttagttagt aaaaatcaag taaaagtaaa tggattatat
    14281 ttaaatgaat ccgtatactc atcttacctt gattttgtga aaaattcaga tggacaccat
    14341 aatacttcta attttatgaa tttatttttg gacaatataa gtttctggaa attgtttggg
    14401 tttgaaaata taaattttgt aatcgataaa tactttaccc ttgttggtaa aactaatctt
    14461 ggatatgtag aatttatttg tgacaataat aaaaatatag atatatattt tggtgaatgg
    14521 aaaacatcgt catctaaaag cactatattt agcggaaatg gtagaaatgt tgtagtagag
    14581 cctatatata atcctgatac gggtgaagat atatctactt cactagattt ttcctatgaa
    14641 cctctctatg gaatagatag atatatcaat aaagtattga tagcacctga tttatataca
    14701 agtttaataa atattaatac caattattat tcaaatgagt actaccctga gattatagtt
    14761 cttaacccaa atacattcca caaaaaagta aatataaatt tagatagttc ttcttttgag
    14821 tataaatggt ctacagaagg aagtgacttt attttagtta gatacttaga agaaagtaat
    14881 aaaaaaatat tacaaaaaat aagaatcaaa ggtatcttat ctaatactca atcatttaat
    14941 aaaatgagta tagattttaa agatattaaa aaactatcat taggatatat aatgagtaat
    15001 tttaaatcat ttaattctga aaatgaatta gatagagatc atttaggatt taaaataata
    15061 gataataaaa cttattacta tgatgaagat agtaaattag ttaaaggatt aatcaatata
    15121 aataattcat tattctattt tgatcctata gaatttaact tagtaactgg atggcaaact
    15181 atcaatggta aaaaatatta ttttgatata aatactggag cagctttaac tagttataaa
    15241 attattaatg gtaaacactt ttattttaat aatgatggtg tgatgcagtt gggagtattt
    15301 aaaggacctg atggatttga gtattttgca cctgccaata ctcagaataa taacatagaa
    15361 ggtcaggcta tagtttatca aagtaaattc ttaactttga atggcaaaaa atattatttt
    15421 gataatgact caaaagcagt cactggatgg agaattatta acaatgagaa atattacttt
    15481 aatcctaata atgctattgc tgcagtcgga ttgcaagtaa ttgacaataa taagtattat
    15541 ttcaatcctg acactgctat catctcaaaa ggttggcaga ctgttaatgg tagtagatac
    15601 tactttgata ctgataccgc tattgccttt aatggttata aaactattga tggtaaacac
    15661 ttttattttg atagtgattg tgtagtgaaa ataggtgtgt ttagtggctc taatggattt
    15721 gaatattttg cacctgctaa tacttataat aataacatag aaggtcaggc tatagtttat
    15781 caaagtaaat tcttaacttt gaatggtaaa aaatattact ttgataataa ctcaaaagca
    15841 gttaccggat ggcaaactat tgatagtaaa aaatattact ttaatactaa cactgctgaa
    15901 gcagctactg gatggcaaac tattgatggt aaaaaatatt actttaatac taacactgct
    15961 gaagcagcta ctggatggca aactattgat ggtaaaaaat attactttaa tactaacact
    16021 gctatagctt caactggtta tacaagtatt aatggtaaac atttttattt taatactgat
    16081 ggtattatgc agataggagt gtttaaagga cctaatggat ttgaatattt tgcacctgct
    16141 aatacggatg ctaacaacat agaaggtcaa gctatacttt accaaaatga attcttaact
    16201 ttgaatggta aaaaatatta ctttggtagt gactcaaaag cagttactgg atggagaatt
    16261 attaacaata agaaatatta ctttaatcct aataatgcta ttgctgcaat tcatctatgc
    16321 actataaata atgacaagta ttactttagt tatgatggaa ttcttcaaaa tggatatatt
    16381 actattgaaa gaaataattt ctattttgat gctaataatg aatctaaaat ggtaacagga
    16441 gtatttaaag gacctaatgg atttgagtat tttgcacctg ctaatactca caataataac
    16501 atagaaggtc aggctatagt ttaccagaac aaattcttaa ctttgaatgg caaaaaatat
    16561 tattttgata atgactcaaa agcagttact ggatggcaaa ccattgatgg taaaaaatat
    16621 tactttaatc ttaacactgc tgaagcagct actggatggc aaactattga tggtaaaaaa
    16681 tattacttta atcttaacac tgctgaagca gctactggat ggcaaactat tgatggtaaa
    16741 aaatattact ttaatactaa cactttcata gcctcaactg gttatacaag tattaatggt
    16801 aaacattttt attttaatac tgatggtatt atgcagatag gagtgtttaa aggacctaat
    16861 ggatttgaat actttgcacc tgctaatact cataataata acatagaagg tcaagctata
    16921 ctttaccaaa ataaattctt aactttgaat ggtaaaaaat attactttgg tagtgactca
    16981 aaagcagtta ccggattgcg aactattgat ggtaaaaaat attactttaa tactaacact
    17041 gctgttgcag ttactggatg gcaaactatt aatggtaaaa aatactactt taatactaac
    17101 acttctatag cttcaactgg ttatacaatt attagtggta aacattttta ttttaatact
    17161 gatggtatta tgcagatagg agtgtttaaa ggacctgatg gatttgaata ctttgcacct
    17221 gctaatacag atgctaacaa tatagaaggt caagctatac gttatcaaaa tagattccta
    17281 tatttacatg acaatatata ttactttggt aataattcaa aagcggctac tggttgggta
    17341 actattgatg gtaatagata ttacttcgag cctaatacag ctatgggtgc gaatggttat
    17401 aaaactattg ataataaaaa tttttacttt agaaatggtt tacctcagat aggagtgttt
    17461 aaagggtcta atggatttga atactttgca cctgctaata cagatgctaa caatatagaa
    17521 ggtcaagcta tacgttatca aaatagattc ctacatttac ttggaaaaat atattacttt
    17581 ggtaataatt caaaagcagt tactggatgg caaactatta atggtaaagt atattacttt
    17641 atgcctgata ctgctatggc tgcagctggt ggacttttcg agattgatgg tgttatatat
    17701 ttctttggtg ttgatggagt aaaagcccct gggatatatg gctaaaatat atgtttgata
    17761 aaaaattatt cctgtgctac taagaaatta tttttatata ataaatattg agatttaatt
    17821 aaaagtcatg tgttattgta atacatgact tttagttaaa atttttctat catttaataa
    17881 tctattattc ttgactattt tataataaaa ttcatatatg gaaatattaa tactaaataa
    17941 ttaatagttg ataaaaaata gataatatgc taaaagcaaa aactaattta gagccttgta
    18001 actgtttatt tgcaattata aaaacatctt taaacatatt gactataata taaaatatta
    18061 actataatac aaaacaatat taattaattt tctctacagc tattcctggt atagttatat
    18121 ttccacccat agttgattca taagttatag ttccagcact tatacctctt atagttatgt
    18181 aatcatcctc taatactctt gaaggagtta ttgatttttt ataactacat agtacaacct
    18241 tatcataatt tccagacaca gctaatctta tttgcacctc atcaccatct tcaataactt
    18301 gaataacctt accttcaaat tttacctttt tgtacttata atcatcaggt gttctagcta
    18361 attggtcata agtaatacca gtatcatatc ctttcttctc ctcttcttct tttttacgtt
    18421 gttcttcagc ctttttagct tcttcagctt ttttagcttc ttcagcttta cgttgatttt
    18481 cagcttcaat agctttcttt tcgtcgtctt tcattttgaa ccatggttca gcatcagaca
    18541 atttgctatt taaagtttct atttctgttt tttgagaatc tataactgat gtttgattag
    18601 aaatgacctc ctcatggtct tcagaacaag ctggtgagga tatattgcca aaaaacacgc
    18661 ccaaaataaa tgccagtaga gcaataccct ttgtgctctt aaagaattta attattttct
    18721 tagagcttcc ttttccttca ttactaaatt cgttaccctc atttttttta gaaaacataa
    18781 tacaatctcc cttttattag atatatttta ttttaaaagt taaaaactta aaataactag
    18841 ttgactaaaa attatatatt catattttcc taaaatatat ttcccctaag cataatttta
    18901 caaaataaag taagaagatt caatatattt tgaaaaaata agataaaaat gtcagattat
    18961 aatataattt tcttgaaggt gaattttata tattaaatta aacataaagt attttatttg
    19021 tataaaacta tattatgatg taattaagtg actcagtgat ttagaggtgg taaaatatat
    19081 atatatgaaa gagcataaat aaattgatat aataaaaaat taaatattaa atattaacta
    19141 taataaaaaa atatctggta ataggtataa tataaaaaga atataccaga aagaaggtga
    19201 agtatgggag aactacaaaa aattccaggg gtagggaaag caacagaaaa atctttaatc
    19261 atgttaggat atacaactat taaatcactt aaagatgcaa acccagcaca aatgtatgaa
    19321 aaggaatgtt taatgcgtgg acagcacata gacagatgtc agttatatgt atacagatgt
    19381 gcagtatatt ttgcatcaac tgaaaatcca gaaccagaaa aattaaagtg gtggtattgg
    19441 aaagattaaa aaatcaaaaa agttagacat aaaaaagagt tgaatatccg ttttaaataa
    19501 taaaaactaa tactcaactc ttttttagtc gtaaatttta tgtaaatcta tttgtatggc
    19561 taaatatacc catcaataaa tgtataaata taccaatcaa caaatgacta aacatactac
    19621 ctaacaaagg attaaataaa ttacttaaca aagcattcta aaacaattaa ttagaaactg
    19681 tttcttcaag ccattttcta cattgctcaa tatttaccat agggtcaaaa ccttggtctt
    19741 ttcccttatt taaaagcata tcacaaggga aagtatcaca ttcaccacaa tgattaagtt
    19801 ccttactttc acagcaagtt ttaaccttac attctccacc ccaaaatggt ttttccatag
    19861 ttgggcaacc agtgcaattt acttgttctt tttttgtaca actgtcacaa cagacaccac
    19921 atcttgattc aaacatgttc aaacatcctt tccattattt aaaaatatta taaaatgatt
    19981 ttagatgact acaaaagtgc aaatagttga ttttaggtca tctaaatgtt aaacataaaa
    20041 ttattagtaa tggtaaattt ataaaaacta ttccaaaaat ctttttgaat atttcaaaac
    20101 acaataaatt acttcaaatc cctttgaata tattttacag cattatagat tgctttaaat
    20161 ctctttgaat attctacaag actatagatt agtttaaatc cctttgaata tattttacaa
    20221 cattatagat tgttttaaat ctctttgaat attctacaag actatagatt agtttaaatc
    20281 cctttgaata tttcaaaaca ccatagatta ctttaaatcc ctttgaatgt tctataacac
    20341 tataaattac ttttaacttt tatataacca taaagttttt atctggcact ttaaatggag
    20401 ttttatatca aatttgcctt ccatcgaata accaaactta atttaattac acattccaag
    20461 agtcaaatat tcattcaata
//
LOCUS       DAEQAF010000070        19304 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.073, whole genome shotgun sequence.
ACCESSION   DAEQAF010000070 DAEQAF010000000
VERSION     DAEQAF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19304
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.073"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            271..660
                     /locus_tag="KRN00_002605"
     CDS             271..660
                     /locus_tag="KRN00_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1828464.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEDMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            980..1489
                     /gene="vanZ1"
                     /locus_tag="KRN00_002606"
     CDS             980..1489
                     /gene="vanZ1"
                     /locus_tag="KRN00_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HBH1828465.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIVNNRVDISEIILNVVIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(1591..1785)
                     /locus_tag="KRN00_002607"
     CDS             complement(1591..1785)
                     /locus_tag="KRN00_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBH1828466.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(2301..2693)
                     /locus_tag="KRN00_002608"
     CDS             complement(2301..2693)
                     /locus_tag="KRN00_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1828467.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            3260..3622
                     /locus_tag="KRN00_002609"
     CDS             3260..3622
                     /locus_tag="KRN00_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828468.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            3606..4313
                     /locus_tag="KRN00_002610"
     CDS             3606..4313
                     /locus_tag="KRN00_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828469.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVVEFTEEDEEELKQNIIENIK
                     KNFDEKKLVQVYKYRGV"
     gene            4333..4752
                     /locus_tag="KRN00_002611"
     CDS             4333..4752
                     /locus_tag="KRN00_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828470.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            4742..5266
                     /locus_tag="KRN00_002612"
     CDS             4742..5266
                     /locus_tag="KRN00_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828471.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNISNYEETFKKTTSIKCRYVDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            5578..6135
                     /gene="efp"
                     /locus_tag="KRN00_002613"
     CDS             5578..6135
                     /gene="efp"
                     /locus_tag="KRN00_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBH1828472.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            6227..6682
                     /locus_tag="KRN00_002614"
     CDS             6227..6682
                     /locus_tag="KRN00_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1828473.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            6845..7555
                     /locus_tag="KRN00_002615"
     CDS             6845..7555
                     /locus_tag="KRN00_002615"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBH1828474.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            7609..8679
                     /locus_tag="KRN00_002616"
     CDS             7609..8679
                     /locus_tag="KRN00_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1828475.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNINQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            8707..12261
                     /gene="smc"
                     /locus_tag="KRN00_002617"
     CDS             8707..12261
                     /gene="smc"
                     /locus_tag="KRN00_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBH1828476.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEIKDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLESSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            12288..13568
                     /gene="ftsY"
                     /locus_tag="KRN00_002618"
     CDS             12288..13568
                     /gene="ftsY"
                     /locus_tag="KRN00_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBH1828477.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDIEEKNEESVNNEGTEEIENFEKIEVEMDSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            13671..14039
                     /locus_tag="KRN00_002619"
     CDS             13671..14039
                     /locus_tag="KRN00_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBH1828478.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            14036..15388
                     /gene="ffh"
                     /locus_tag="KRN00_002620"
     CDS             14036..15388
                     /gene="ffh"
                     /locus_tag="KRN00_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBH1828479.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            15426..15698
                     /gene="rpsP"
                     /locus_tag="KRN00_002621"
     CDS             15426..15698
                     /gene="rpsP"
                     /locus_tag="KRN00_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBH1828480.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            15763..15990
                     /locus_tag="KRN00_002622"
     CDS             15763..15990
                     /locus_tag="KRN00_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBH1828481.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            16098..16613
                     /gene="rimM"
                     /locus_tag="KRN00_002623"
     CDS             16098..16613
                     /gene="rimM"
                     /locus_tag="KRN00_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBH1828482.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVAREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            16622..17317
                     /gene="trmD"
                     /locus_tag="KRN00_002624"
     CDS             16622..17317
                     /gene="trmD"
                     /locus_tag="KRN00_002624"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBH1828483.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            17502..17852
                     /gene="rplS"
                     /locus_tag="KRN00_002625"
     CDS             17502..17852
                     /gene="rplS"
                     /locus_tag="KRN00_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBH1828484.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            18173..19069
                     /gene="ylqF"
                     /locus_tag="KRN00_002626"
     CDS             18173..19069
                     /gene="ylqF"
                     /locus_tag="KRN00_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBH1828485.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
BASE COUNT         8252 a         1760 c         3451 g         5841 t
ORIGIN      
        1 aagcttatag attataatga aatataatac atgttgcaat aataaaacga actaaaatta
       61 tcacactaaa gcataaaaca tactctaatc atgttagata aatttttgaa tatataatcc
      121 aaaagtactc tctaaagtag agtacttctt ttttattaat tatttttata tagaataaat
      181 tggaatttat atttattcca atctaattga ttacatacac ttattgttat aaagtttagt
      241 tatacataaa ttggtaagag gtgtaaacta atgaagatta ataaattacc acatgcagaa
      301 ctaaaactaa tgaagtatat ttggggagta gatgatgtat tagcctcaag agatatcata
      361 gaagacatga agttgaaata cgattggaaa aagagcacaa cattgacatt tttaaaaaat
      421 ttagtagata agggcttttt aactactgat aaggtagata gatgtacgca ttatactata
      481 gctataaaag agaaagatta cttaaaagtt gagacaaaga gtttttttag ttttatgcat
      541 aacaattcat ttaagagttt tatttcagca ctacatgatg atgaagtttt agatagtaag
      601 agcttggaca aattagaaga atactttaaa aatttgaaag aagaagatat tgatgactaa
      661 taaatctatc agtatctttt tagtttgaga caattgagag tagcgttttg atttaatgtt
      721 agtgttatgt gatggtaaaa cattataaag aaaagtgctt atttccttag tatctgatag
      781 taaaaaaaat atagaaaata ataccgatta aaatttaaag atatatgaaa tactacaata
      841 gcttaaatca tgtaaatatg ataaagatat tgaaattata aaaggaatat aattttagaa
      901 gaaatagttg acagataaat taccttacta tattattgta ttaataaaat aatacaataa
      961 tatagtaagg aggtaataaa tgaaatctag aaaacataat attacaaaag gattatttat
     1021 agtttacata attattttaa catggataat actatttaag ttgcaatttg atatctcatc
     1081 tcttgaaacc atgaatctta gaagcataaa cttagtacct tttgcggggt cacttatagt
     1141 taataataga gtagatatat cagagattat attaaatgtg gttatatttg taccatttgg
     1201 gatatatgtg tgtatgctaa aagaagaatg gagctttata aaaaaagtta tacctatttt
     1261 tataactagt ttagcatttg aaacacttca atatatattt gcactaggtg caagtgatat
     1321 aacggatttg ataggaaaca cactaggagg aatcatagga atagctgttt ttatgctatt
     1381 atcgaaaata tttaagaata ataccataaa aattatcaat gtattggcat tgattgtgac
     1441 aattattgtt gtattatttt taggattagt tatttttgca aacttataga aataagtata
     1501 tatgtttagc ttaaaataaa acgtaagata caattacata taaaattatt tacacataaa
     1561 aagcacctat acaggtgctt tcctaaatta ttaaagaatt attgtatctt gaaactcttg
     1621 tatgttcaat tcttgatttt ctcttgtttt ttctaataaa tctaacgcac aatttataca
     1681 aactttaatt tctgcattgg tatttttctc atagtaagtt atatatttat ttctatattt
     1741 atctatttct tttccacaac gactacacat tacaattacg ctcatatctt agttcctcca
     1801 tctctaatta ttcttaatat attcaataat atcacttttc tgaaaataat gattgttaaa
     1861 actgtatcaa atttagattt actttttatt ataatgcatt ttaataaaaa aataaaggtt
     1921 ataggtaaaa tatttataga aaaaagtata ttattgaata gattataaaa ttttattatt
     1981 ttttagcagt gttaaataca cattaatatc tataaagtga caaaataaaa aatactattt
     2041 aaatagatat taaaaaattg ataccaagta tttgtttgct atatgaataa caatttattt
     2101 aggaacttta ctttaacact gtataataat aaagtaattg ctaaaaacgt ttgatgattt
     2161 ggatgtattt ttagaaatta gaaaaatata tacttactga ctaatgataa tcttatatgt
     2221 attttagttt gagtgattta agaaaagtgt tttgaatggg gattatttta tagagtaaat
     2281 aaatatataa tagtagaaaa ttacatataa agagtagtgt ttatttcatt accttcttta
     2341 tctgttccga tagggtcttg tagagatact tgagttttat tttttttgtt agatctaata
     2401 ttcattaaaa tctcattttc aatacatcta gaagcatatg ttgctaatcg agttccttta
     2461 tctatgttat aagtttctat agctttaatt aatcctattg tacctatgga tattaaatca
     2521 tcctgatctt ccgttgaatt attatatttc tttgctatat aagctactaa tctcatgttt
     2581 ctttcaatta atgtatcttt tgcactttta tcgttttcta ttttaaattt agttaaatac
     2641 tcaatctctt cttcaggggt taagggtttt tcaaaagatt taagagctgc caataggtca
     2701 cccccttttc aacggtcact ttaaattata tgaaggagac ttatccaagt tgactgttat
     2761 ctaataaaat aatatgcata tttttagaat ttaaaacata tatttgcaaa cttttgaatg
     2821 gaatatgaca taaagagtgg gaatttaaat ttaagttttt gttgtatata tatgaaataa
     2881 ggcgaagaaa ttattgattt ataaagtata aattggaatt gaggtgtcaa taaatataaa
     2941 aggaaatagt atttatatat gttttggtgt tgaagtaaaa gattaatgca aagcattaga
     3001 gtctataaaa atatgaatat aggaggtgta attttacaat acttaaaaaa gtaaatgtaa
     3061 ttaattgttt gtataaagtt gattacaagc aaaagtatca gtcatagtta atactgttaa
     3121 gggtgaaggt ggtgtgttaa tttatatatg tatgggaaga aattttgatt acaatgaaaa
     3181 aacttacaaa agatatttat gaaaaaactt atagttaaat gtttatatat aaaatattat
     3241 ttaggggttg tttttattat tgaaaataag aaagagtggt tttatatcaa ttgaatgtat
     3301 aataagtatt gctatattat atgtggctgt ttatttagtt tctacatcat tgtataattg
     3361 ttatagtttt atcagtagaa atatatctga cagagaaatg ttaagtacag caaaaaaata
     3421 tatagaagat gagaagtata gaatacaaaa tagtaagtat gagttaattg aagataagat
     3481 agaaaaaaat tacataaatg gatatgaaat taacagtaaa atagagcaaa ttttagatta
     3541 ttatcaatgc tatgaaataa atatagagat aaaaaatgaa tttaaaaaac tgaggtttaa
     3601 tagctatgtt actagaaaat aaaggctcta tattaataat aacattgata atattttcta
     3661 ttataagtac tgtgtgcatt atgtgtatag gtttaattta tacacataat aatatgtttg
     3721 agttaggata caaagacatt caactaaaag aaatttcttt aagtggaata gaaatatcag
     3781 taagtaatgt actttcttgt gttgaggaag ctattgatgt atctaataat gaagacgaat
     3841 ttagagaata tttcttagga aataatatga ttgaatgtat aaaaaaaata aaagatacat
     3901 cttatagtag tttagaagaa ctttctttaa aagtagaaaa taatactatt tatgacagag
     3961 gagatttttt tgaatttgat atagaaagta atgttagaga aaaagaattt ttaaaagcaa
     4021 taaaagtaag agtgaaaatc aaaaatccat ggataggaat tgatattgaa gattatatgg
     4081 ataaatctaa taacaataaa attgatgaca aaacattcaa taattataaa gcatctgaaa
     4141 ataatgaaat tctaaatcaa tttaaaaatg aaagtgaaaa tataaggaat caagaggttg
     4201 ttgaatttac agaagaagat gaagaagaac ttaaacaaaa cataattgaa aatataaaga
     4261 agaattttga tgaaaaaaaa ctagtacagg tatataagta taggggtgta taactttgaa
     4321 aaaagaagga atgtgactgt aatagaatta atagtatcta tcagtataat actcttgata
     4381 gttacattat cttttccaaa agataatctt gaaaatcata aaataaattt atttgcacgt
     4441 caactttgtt cagatataag gtatgttagg cgaattaata tgtttagcaa ctacaataca
     4501 tatatatatt atataaatca aggtaaacac gaaggttatg tattgagaaa agatggtaaa
     4561 aacattaaat caataatgct acctaaaaat gcaaaaatag ctaggagtat tgaaataata
     4621 aagtttaaat ctgatgggtc gcctcaaaag gcgtctacaa tagagatata taataataga
     4681 ttaagaaaaa ctataacaat aacacctgta agtggaagag tacttctgaa agagggaaaa
     4741 tatgaaacat aaatatggtt acttgctttt ggaaagtgta gtatcattgt cttcaatggt
     4801 gataattata ctagttttat attctatatt tttgtctaca ataaacttaa agttaaaagt
     4861 agaagataag atagaactac aacaacaaag tcttgaaatc ataaaatcta tggaaggaat
     4921 tattagcaat tctatgggaa taatgaatat atctaattat gaagaaacat ttaaaaagac
     4981 aacgtctata aaatgtagat atgtagatga aaataataat gaagaaggca taagtaataa
     5041 agaaattata ttgaatgaaa gacgaaataa gttatttgta aattctttaa atggcgaaag
     5101 tagtcaagca ggtggttatg aaattggaga ttatgtagat gaaatgtatg tatcaattac
     5161 taataatggt caatatgtta atattaaatt gaaattatca aaacgtagtc aaaaatatga
     5221 gactgatttc aaaataaaag tatggaattt tagtgaaagt atataaaaat acataaattt
     5281 aagagaaaga aatgacatca ataagtcata taaaatataa ttattgagaa ctatataact
     5341 aaataatatc aatatgtaaa gtgtatagat taagaatata gaggataata ataaaaatat
     5401 agaataagta atttgccaaa tacttgttta tattgtataa cttatgatat tatgatatta
     5461 gtaaaaattt gtaatcctga cttgacagaa ttcaagtaag agatataatt ttaaaggcat
     5521 agtaatgtaa aatttactaa aaaataagaa atttatttta atatggagga acaaaaaatg
     5581 gtatcagcag gtgattttag aaaaggtgtt acatttgaaa aagatggaca accatgttta
     5641 gtagttgatt ttcaacacgt taagccaggt aaaggagctg ctttcgttag aactaaatac
     5701 aaaaacttaa aaacaggagc tataagagaa gaaagtttca atccaagtga aaaattccct
     5761 aaagctgtta tagatacaag acaaatgcaa tatctataca atgatggtga gttatattat
     5821 tttatggatc aagaaaattt tgaacaaata ccattaaact atgagcaagt tgaagatgca
     5881 attaagttct taaaagaaaa tgaagttgct acaataagat tttaccaagg acaaccattc
     5941 caagtggaag cgccaaactt tgcagagcta gaagttacag atacagagcc aggtataaaa
     6001 ggtgatacag caagtaatgt aactaaagca gctacagttg aaactggagc agttgttcaa
     6061 gttccattat ttataaatac tggagataaa gtaaagatag atactagaac aggtgaatat
     6121 ttatcaagag tataaaaatt tatgtatata aaagcttata tgtcttaata atataagata
     6181 tatgagcttt tagtttatat ataaaaaaga aagcgagggg tgttacatga aacatttata
     6241 tgaagaagtt gcatacttaa aaggcctagc agaaggacta gaaataagtg ctgaaagtaa
     6301 agaagggaaa atgatacata aaatagttga tgcattagaa gtatttgcag atgctattgt
     6361 aacattggat gaagaacaag aagaacttca agattttgtt gaatctatag atgaagattt
     6421 agcagattta gaagaagata ttgctgacat ggaagaagat ctttatgaag aagatgacga
     6481 tgaggatgat gaggacttca gctatataga aatggaatgc ccaaattgtg gagagttagt
     6541 agaaatagac gaagatttgt tatatgatga tgaagtagat gttgtttgtc ctgattgtaa
     6601 ggctgtgata ttatcatcag aagatgattg tgatgatgat tgtacatgtg gtggttgttc
     6661 aagttgtgat gatagagagt aaaaattcat aagaattaaa actgcctatg atgcctatga
     6721 gatattttgc ttcataggta gttttatttt tatgaggaag ggtattatgt attttggttt
     6781 tgcaatactt ggacaaaaat agtacactag aatttataga ataggatttt ggagggatgt
     6841 aaatatgaaa ataagtaaaa aattactaga taatatacaa agatttgaaa atgttataaa
     6901 ttataaattt aaaaataaag aatatatact agaagctctt actcatagtt catattctaa
     6961 tgaaaataaa aaatataatt ttaacgaaag attggaattt ttaggggatt cggttttagg
     7021 catagtgata agtgattatt tatttaatga agaagctaat ctgcccgaag gggaactaac
     7081 taaacttaga gcaaatatag tttgtgaaga ttcattaagt gaagtagcta atgatataaa
     7141 tttaggtatt cacatgttat taggtagagg agaagaagca acaggaggaa gacataggac
     7201 ttcaatatta gcagacgcat ttgaagctgt aatagctgct atatatcttg atggaggttt
     7261 tgaaagtgca agacagttta tacttcatca tatggaaaat ataatttatg attcaagaaa
     7321 aggaaatata tttagagact acaaaacgca tcttcaagag gtgttacaag ggaatggaga
     7381 aaataatatc tggtacaggc ttatagaaga aaaaggacca gaccataata aaagatttgt
     7441 aatggaagtt ggaattaatg acgatgtact tggtatagga gaaggcaaga gtaaaaaaga
     7501 agctgaacag ttagctgcta aaatagcttt aaagaaaaaa ttatgggaaa aataaatata
     7561 atatgtaaaa atataaaaag aaatatttat attagaagga tgttgtagat gaaaaagaga
     7621 attataccta tatttgttcc tcacaaagga tgtcctcatg attgcatatt ttgtaatcaa
     7681 aaaaaaataa caggtgtgag tactgatgtt actagtgaag atgcaagaaa tataattgag
     7741 gaatgtttag agactataga taaagatgca gatgtagaaa tagcattttt tggtggtagc
     7801 tttactgcta tagatattga tatacaaaaa agtttattat cagttgctaa agaatatgta
     7861 gaaaaaggtc ttgtaaaaga tattagaatg tctacaagac cagattgtat tgatgaagat
     7921 atattaagta tgttaaaaga atataagaca agtataattg aactaggagt acaatcctta
     7981 gatgaaaaag tattattaga tagtataaga ggtcatcaat ctgaaattgt atacaagagt
     8041 tcaaagatga taaaaaatag tggaatcaaa cttggattac agatgatgat tggtcttcca
     8101 gctgacacag aagaaaagtg tatatttaca gcaaaaaaat ttgtagagct aaaaccagat
     8161 tgtgttagag tctatccaac tttggtagta aaagatacag gtcttgaaaa gttaatggaa
     8221 caaaataaat ataatccatt tactcttgaa gagagtgtaa atatagtaaa aaaagttctt
     8281 gtactgtttt atgttaataa tatcaatgta ataagagttg ggcttcaagc tactgatgat
     8341 atacaaattg gaaaagctgt tttagcagga ccatatcatc ctgcatttag agagttggta
     8401 gaagcagata tgataaaaga ttatttagaa tttgttattt tgcaaaataa aaatataaat
     8461 caaatgttgg tcaaatctaa taaaaagaat atttctaaaa tcataggaaa taaaaaaaca
     8521 aatgttaaat atatggaaga aaaatttggt gtgcttttaa aaacacaaga atcagattta
     8581 gatataaatc aattagaaat tgtgttagat gggaaaagtt taattagtgc taatatgaga
     8641 gacattcata gaaaattgta tgacatttat gacctttagt tttaataatg aagggagaga
     8701 aaagatttgt atttaaaaag actagagtta aagggattta aatcctttcc agtaaaaaca
     8761 gatattattt ttaaagaagg aataacagcc atagtaggac caaatgggag tggaaaaagt
     8821 aatatatctg atgctgtaag atgggtatta ggagaacaga gtattaagag tcttagaggg
     8881 gataaactcg aagatgtaat atttgcaggt acagatacaa aaaaacctat gaattattgt
     8941 gaagtggctc ttactattga taattctgaa aatcaattgg aattagattt tacagaagta
     9001 actataagaa gaagggctta tagaaatggt gaaagtgaat tttttctaaa taataaaagt
     9061 tgtagattaa aagatataaa agaagtcttt ttagatactg gtattggaaa agatggttat
     9121 tcaatcatag aacaaggaaa agtagatgaa atattaagta ataatccttt aagcagaaga
     9181 aaagtttttg atgaagcttg tggcatatca aaatatagat ataaaaaaca ggaagcagaa
     9241 aggaatttaa gtaatacaaa ggaaaattta gaaagaatag atgatgtata tatagaaatt
     9301 gaaaatcaat taaagcctct ttttaatcaa cagacaaagg caaaaaagta cttggaaata
     9361 agtgaaaaat taaagacact tgaagtaaat agctttataa gagaaattga aggaatagaa
     9421 aaagaattaa gtgaggttaa tgaacatcgt aaggttattg aaaaggagct caatgaaaaa
     9481 gaagaacaaa aaaatgttgt agagaaaaag caagaagata ttaataaaga ggtagaggta
     9541 ttacaagatg taattgaaaa atctgtagat tatataaatt caattaaagg agttatatca
     9601 aaaaaagaat cccaaataaa tttaattaag gaaagaataa gaaattttac gaatgaaatt
     9661 agtagaaaaa atttagaaat aaaggatata aaagagaagc taaatgaaaa taagcaatac
     9721 ataaaagaat tagaaagcaa taaattatca ggtagtgaag aactatctac cttgcaggaa
     9781 aatataaaag tattggaatc aagtaaagat aaacaaaaaa ttaagttaga atccctaaat
     9841 aatgagatag aattattgaa agaaagtata attgatatat taaataagaa acaagagttt
     9901 agtaataagc tgtccacttt aaacgcaaat aaagaaaata tgaatatcag agatgaaaat
     9961 ataaattcag agataacaga gttaaacaaa aatattgaaa taaaatcatc tgaattagat
    10021 actataaata aagaatttaa tatgcaaaat gaaaatttaa agaatgtaaa taatagacat
    10081 aaagaattat caattaattt gcaggattca attagtgaac acaataaact agaagatgaa
    10141 atacagaaaa gtaaatataa tttaaatgga tataattcaa agttaaatgt ctatatagat
    10201 atggaaaatc attatgaagg atttaataga ggagtaaaag aagtactaaa aaataaaaat
    10261 ttaaaaggag ttcatggagc attaggacag attataaatg tacctgaaaa gtatgagaaa
    10321 tctatagaag cagctcttgg tgcttatatg caaaatataa taactgataa tgagtttagt
    10381 gctaagtctg caataaacta tctaaaacag aataatttag gtagagtaac atttcttcca
    10441 ttaaatataa ttaaatcaaa taaaataagt ctaggaaatt taaaagcaaa tactaagttc
    10501 ataggaatag caagtgattt aattacattt gatgaaaagt atagaaatat aattgaaaat
    10561 atacttggaa gaacaatact tataaataat atagatgagg gcataaaatt tgcaaaagaa
    10621 actggtcata ggtttaaaat agtaacttta gatggtgaaa tcttaaatcc aggaggttct
    10681 ttgactgggg gaagtctaaa aactaatggg aatatactat cgagaaaaag atacattaat
    10741 gaatatacag aaaagataag taatatcaag aatgaaattt cacatctaga attaaaaaga
    10801 gaatctttag acaaagatgt gaaaaatatc aaaaatgaaa ttgattcaca tgaaagtaaa
    10861 ataaaagatt tagaaaaaag tataataata aaaagtacaa gtataaagaa tgttgagtct
    10921 gaaattgaat cgttaaaagg tagtattact aaattagaaa atgagaagaa tgatttaaat
    10981 tctaacctaa attatacact tgaaaaaagt gatgatgtta gaaaagatat ggaagagtta
    11041 gatgacttat acaataaaaa taaagaaaaa attgatgcat tgaatgagga aataaaaaga
    11101 tacaatgatt tatatgataa agaaaaatct gaatttgatg aattgaactt aagtttagtg
    11161 aagaaaacag aagtttacaa tagtatagtt agagatataa aaagaatatc tggtgaaaat
    11221 tgtgagctag aagaaaaaaa taaacaatta gaagagtcat taaattatga agaacatgaa
    11281 ataattaaat tacaagattc tatactcact gaagaaaaag aaaaagaaaa tttaacaaaa
    11341 caactagggg atagtaatag aaatcttgaa actagaaaaa tagcaaaaga tgatttaaaa
    11401 aatagttttg atgaaattaa taaagaatta aaaactatag atagacagca tatagaactt
    11461 aaagaaagtt tatttaaagt tggtggaaga ttagaaagat taaaaactag tcaagacaca
    11521 tatataaata agttgtttga gcaatatgat atgaccttag tacaagcatt ggaaattaaa
    11581 gatgaagatt tggatataga tagaaaattc ttagaaagtc taaagagaga aataagaagt
    11641 cttggaaata taaatataga ctctataaag gaatatgagg aaataaaaga aagatacgat
    11701 ttttatagcg aacaaaagca agatttagaa gagtctatgg aagagataga aaaacttata
    11761 catactttag aagaaaatat gaaatctgaa tttgaaatta agtttgaaga aataagtaaa
    11821 aattttaaat atgtatataa gagattattt ggtggaggtt gtggagaatt aactatttta
    11881 gataaagaaa atttattaga aagtgatata ctaataacag ctcaaccccc aggtaaaaaa
    11941 atgaaaaatt taaacctatt atctggtgga gagaaagctt taacggcaat aagtatatta
    12001 tttgctatat tgattacaaa gccaacacca ttttgtatat tagatgagat tgaagcgcca
    12061 cttgatgacg caaatatatt tagatttgga gaatttttga aggatttatc taaagagact
    12121 caatttatat cagtaactca taggagagga acaatggaag ctgctgatta tatctacgga
    12181 gttacaatgc aagaaaaagc catttcaaaa gttattagtt taaaattaaa agaagctcag
    12241 gaaataacag atattatata acttagattg acataggagg aataacagtg ttaaaaaaat
    12301 tatttggttt tggaaaagac aaggaaaagg aaatagaaaa aaaagatgct gaagaagaaa
    12361 tagaagttga agacagtgtt gataatttag aaaacttgga agaaactatt ttttcaggac
    12421 ttgaagaaga agtgatagat aaagtggaag atattgaaga aaaaaatgag gaaagtgtca
    12481 ataatgaagg cactgaagaa atcgaaaact ttgaaaaaat agaagttgag atggatagta
    12541 atggaaaaga agtagaaaat atttcaaata atgattctca agaagagata atcgaagaat
    12601 tagaaaatta tgatgaaatt gagtctaaag agatagaaga taaagaagat aagaaagtta
    12661 acttgtttga aagactaaaa caaggattga caaaagcaaa gcaaggaata actgatagaa
    12721 tagatgaagt tttaaaatca tatacaaaaa tagatgaaga attacttgaa gatttagagg
    12781 aaattttaat aacagcagat gttggtgtaa atacaactat ggatataatt gaaagactaa
    12841 gagataaaat aaagcaaaaa ggtattactg aaccaataaa ggtaagagaa gaacttaaat
    12901 ctatagttga agatattctt acaaatgaaa actctacact agatatagaa ccagcaccat
    12961 gtataatatt aatggtgggt gtaaatgggg tcggtaagac tactacaata ggtaaactag
    13021 caaatagata caaaaaagat ggtaaaaaag ttttattagc agcagcagat acatttagag
    13081 cagcagcaac agagcaatta gaaatttggg caaatagaac caatgtagac ataataaaac
    13141 atcaagaggg agcagaccct ggagctgtag tatttgatgc tataaaagct gcaaaagcta
    13201 gaaaaacaga tgtattaata tgtgatacag caggaagatt acacaataag gctaatctta
    13261 tgaatgaact tggaaaagta tttaaaatag tagatagaga atttccagaa gcaaaacgtg
    13321 aagtacttct tgtggtggat gctacaacag gtcaaaatgc agttgttcaa gcaaagacat
    13381 ttaaagaagt tgcagatata acaggtatag tacttacaaa acttgatgga actgcaaaag
    13441 gtggagtagt ccttgcggta aaatcagaag tagatgtacc tgtaaaactt attggagttg
    13501 gagaaagtgt agaagaccta caagatttca atgcaaaatc attttcagat gcattatttg
    13561 gtaactaatg ttcttttaaa aataatggtt gacaagagtg ttgttatgat ataaaataca
    13621 atagtgtaaa gtaaataacc tttacagtat actgctagga agtgtaagat atgaatatag
    13681 aaaaaatggt cgaaattgga ttgttatttg aacagtataa agaattatta actgacaagc
    13741 agaaagaaat agttgctcta tactatgaag aagattattc tttaggtgaa attagtgaaa
    13801 atctgaatgt atcaagacaa ggtgtttatg ataccttaaa gcgttcagaa aaaatactaa
    13861 gagattatga agaaaagtta cacttagtat caaagattca agagcaggaa aaaaatatta
    13921 agattataaa agataaaatt attgacatta aagaagattt attgcacaat agagattgtg
    13981 ctaatttaat ccctaagcta gaaaatatag aagatgtatg tagggagatg ataaaatgat
    14041 atttgaagga ttgtctgata aactacaagg ggcatttagt aagttaaaat ctaaaggaaa
    14101 acttacagaa gtagatgtaa aaaatgctat gagagaagtt aaacttgctc ttcttgaggc
    14161 agatgttaac tttaaagtag ttaaagattt cataaaaaaa gttcaagaga gatgtgttgg
    14221 gcaagaagtt atgcaaagct taactccagc tcagcatgta atcaaaattg taaatgaaga
    14281 gcttacaagt ttaatgggag atgtacaaag taaagtaatg atttcctcaa agcctcctac
    14341 aattttaatg atggttggat tgcaaggtgc aggtaagact actacagcag gaaaacttgg
    14401 aggatatttt aaaaagcaag gtaaaaaacc tctattagta gcttgtgata tttatagacc
    14461 agcagctata aagcaacttc aagttgttgg agaaaaattg gatatacctg tattcaatat
    14521 gggagataaa gaaaatccag taaatattgc gaaagcaggt ttaagccatg cgattaaaaa
    14581 tgctaatgat ttagttatta tagatacagc tggtagactt catatagatg aagtacttat
    14641 ggatgagtta aagtctatta aatcagaagt taagccacat gagatacttt tggttgtaga
    14701 ttctatgaca ggtcaagatg ctgtaaatgt tgcagaaagc ttcaatgagg cacttggtgt
    14761 tgatggagta gtattaacta aattggatgg agatactaga ggtggtgctg cactttcaat
    14821 aagagcagtt acacaaaagc ctataaaatt tatggggatg ggagaaaagc tagatgatat
    14881 agaacctttc cacccagata gaatggcatc aagaatatta ggtatgggag atgtcttaag
    14941 tttaatagaa aaagcacaag aaaatataga cttagagaaa gctaaagaat tagagcaaaa
    15001 aattaaaaaa caagagcttg attttgaaga tttcttacaa caaatggaac aaatacaaaa
    15061 tatgggacct cttgacaaga tacttggtat gatacctggt atgggaaatg taaaagacca
    15121 acttggagat gtagatttga atggcaaaga aatgaagaga acaaaagcca taattcagtc
    15181 aatgactaca tatgagagaa gaaacccagg agtattaaat gcttcaagaa agaaaagaat
    15241 agctaaaggc agtggaacta gtgtacaaga tgtaaataga cttataaaac aacttaatga
    15301 aatgaaaaaa atgatgaaga tgtttgctgg ttcacaaaag agtatgaaga aaaggggcgg
    15361 cttaggcggt ttaccttttt ttaaataaaa tataaaaaag taaaaattat tcggaggtga
    15421 ctgtaatggc agttaaaata agattaaaaa gaatgggagc taacaaaaaa cctttctaca
    15481 gaatagtagt agctgattca agagctccaa gagatggaaa atttatagaa gaaataggat
    15541 actataatcc aatttctgaa cctaaacaag taagaataaa tgatgaaaaa gctataaaat
    15601 ggttagctac tggtgctcag ccaacagaag tagttaaaaa attacttgta aaaaacggag
    15661 taatagaaaa attcgaagct tctaaacaag caaaataatt ttttcttggc aattagttta
    15721 agtaagggct cattgctaag gttactttag gagatgaaat atatgaaaga gctagttgta
    15781 gatatagcta aggctctagt tgataatcct gactcagttg ttgttgagga atttgaagat
    15841 aatgatggta tcgtcttaaa gcttacagtt gctcaagagg atatgggtaa ggttattggg
    15901 aagcagggaa gaatagctaa agctataaga actgtcgtaa gatctgttgc aaatagagaa
    15961 aatataaaag tttctcttga gatagtataa aataggagga ttaggtataa tgcctagtcc
    16021 tttttatata aatgcgtagt ttaagatttt atgatgatat gaccacataa gattaaattt
    16081 tttaagaagg tgataacatg aaagaaaaat taactcattt taaggtaggt caaatagtaa
    16141 atacacaagg tttaaaaggt gaagtaagag tttatccgct tactgatgat atagagaggt
    16201 ttgatgaatt aaaagatttc tatctgggaa aagatttaaa taataaattg gctgttgaaa
    16261 aagtaagata caaaggttct atggttataa tgaagataaa aggcatagac agcatagaga
    16321 aagcagaaaa actaaaaaat aaatttatgt atgtagctag agaagatagc agagagcttg
    16381 aagaaggcga attttttata gcagatatga ttggaatgga agttttaact gtagatggaa
    16441 aatatgtagg gatactagaa gatgttcttc aatactcagc aaatgatgtc tatgtagtaa
    16501 aaggtgagga agataaagaa tttatgatac cagctataaa aaaatttgta cctacaatag
    16561 atattgatga aagaaaaatg attatagacc ctattaaggg aatgatagat taggtggtaa
    16621 tatgagattt catataatga cactttttcc agaaatattt aattcgtaca tggatgaaag
    16681 tataatgaag agagcagttg aaaaaggtat aattgaggtt catatatata atataaggga
    16741 tttttctaat aataaacata aaaaagtaga tgattatcca tttggaggag gagcggggat
    16801 ggtaatgact cctcaaccta tatatgacac atataagcat ataataacaa ctcataatat
    16861 aaataaccca agtgtaattt atcttactcc aaaaggtaag gtatacaatc aatctatggc
    16921 aaagcagatg tctttaaaag aagatataat actactatgt ggtcattatg aaggaataga
    16981 tgagagaatc attgatttaa tagttactga tgaaatttca attggagatt atgtattaac
    17041 tgggggagag ctcccagcac ttataatgat agattctata tcgagattaa taccaggtgt
    17101 attaaaccaa gaagaatcat ttgaagaaga atcatttaaa gataacttat tggaatatcc
    17161 tcattacact agacctagag attttgaagg attaaaagta ccagaagtgc ttttatcagg
    17221 gaatcataag aagatagatg agtggagaag agaagaatct ataaggataa ccaaagaaag
    17281 acgatttgat ttatataaaa aatctaatga aaaataaaaa tctaatgaaa aattaatata
    17341 tatgtataca ataaagtacc tataaatgga attaaaaaca taaaagtgct tgtaataact
    17401 attgaagtat agtataatat aaaatgttga aaatacgggc gttcctctgt ttacactggt
    17461 cgggtagtta agaacgtcta tgatatctag gaggaagaaa gatgaatgaa atgctaagag
    17521 caattgagca agaacaatta aaaaatgaag ttcctaattt tggacctggg gacacagtta
    17581 aagtacacgt tagaattata gaaggaaaaa gagaaagaat acaagtattc gaaggtgtag
    17641 tattaaagag acaaggtgga ggagcaagag aaactttcac agttagaaaa atgtctttca
    17701 atgttggtgt agaaagaact ttcccagttc actctccaaa aatagaaaaa atagaagtta
    17761 ctagaaaagg taaagtaaga agagctaaac taaactactt aagaggtaga gtaggtaaag
    17821 ctgctaagat aaaagaagct agaaataaat aattaaaaac tttacttata aatggggggc
    17881 tgatttatca gtcctctttc tattttaatg aaaattacag caaataatta tactagaaat
    17941 aaatagaaat atttgttgaa aatatacatt atttatctat gaatttatag cttttaaaat
    18001 gaaaaataaa attggtaaat attgcattat attttgtaac aatattaaaa ataagaaaat
    18061 agtattatgt aaagtatgac gttaaaaaga tgacaatatt atagtttgtt aagatagatt
    18121 ttttaagtgg aattaggata taataatata atattaataa ggagtgatac atgtgtcaaa
    18181 tgaatacgaa gagtatctta tgaatgacaa tctacatata aactggtatc caggtcatat
    18241 gaaaaaaact aaggagttag taaaaaataa cttaaaattg attgatgtag taattgaact
    18301 tttggatgct agaatcccgt ttagtagtaa aaatccagac atagacaggc ttgtaggaga
    18361 taagccaaga gttgtcgtac ttaataagag tgatatggca gatagggata aattgaatca
    18421 atggattgaa tactataaga aaattaatat caaagctata ccagtagata caataaaagg
    18481 cgttggtata aataagataa tcgaagaatg taaaaatgta actagagaaa aaatgagttc
    18541 tttaaaagac aaagggagaa aagaaagagc tatacgaata atgatagttg gagttccaaa
    18601 cgttggtaaa tcgtctctta taaacaaatt aacaggtaga aaaagcactc aaactggaga
    18661 taagccagga gtaacgaaag ggaaacaatg ggttagatta aagggaaatc ttgaactttt
    18721 agatacacct ggaatacttt ggcctaagtt tgaagaccaa gaagttgcat taaatttagc
    18781 atttagtaga gctataaagg atgagatttt agatactgaa actttggctt taagacttat
    18841 agaaaaactt atgaaaatag aacctgagaa gttgaaagcc agatataagt tagattgtct
    18901 aggagaaact ccaattgaaa ctatggatat gattggtcat aaaagagggt ttataacagg
    18961 taaaaaagaa ctagattata cacgcatagc cacaactgta ttaaatgaat ttagagatgg
    19021 aaaaatagga aatataacat tggaagttcc agaaaacgtt aaaagataga ttttaaaaca
    19081 aaatcaaaaa tttaatgtta aaaatttaaa aaagcctttt agcaaaggct tttttatttt
    19141 tttgaaatat agacaaatat cttcatataa aagtataaat taggttagaa aacctttaaa
    19201 aatattaatt taagacaaat atacctaata ttttgaaaat taaaatgagt gtgattattt
    19261 aaaattttag catattgact tgcttgtttc gtataatata taat
//
LOCUS       DAEQAF010000071        18925 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.074, whole genome shotgun sequence.
ACCESSION   DAEQAF010000071 DAEQAF010000000
VERSION     DAEQAF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18925
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.074"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(83..2053)
                     /gene="ftsH"
                     /locus_tag="KRN00_002627"
     CDS             complement(83..2053)
                     /gene="ftsH"
                     /locus_tag="KRN00_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH1828486.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(2087..3475)
                     /gene="tilS"
                     /locus_tag="KRN00_002628"
     CDS             complement(2087..3475)
                     /gene="tilS"
                     /locus_tag="KRN00_002628"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBH1828487.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKGSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(3658..4086)
                     /locus_tag="KRN00_002629"
     CDS             complement(3658..4086)
                     /locus_tag="KRN00_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBH1828488.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEEDIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(4103..4909)
                     /locus_tag="KRN00_002630"
     CDS             complement(4103..4909)
                     /locus_tag="KRN00_002630"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBH1828489.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(5111..5596)
                     /locus_tag="KRN00_002631"
     CDS             complement(5111..5596)
                     /locus_tag="KRN00_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBH1828490.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(5647..6306)
                     /gene="spoIIR"
                     /locus_tag="KRN00_002632"
     CDS             complement(5647..6306)
                     /gene="spoIIR"
                     /locus_tag="KRN00_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBH1828491.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(6451..7131)
                     /locus_tag="KRN00_002633"
     CDS             complement(6451..7131)
                     /locus_tag="KRN00_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1828492.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(7115..8005)
                     /locus_tag="KRN00_002634"
     CDS             complement(7115..8005)
                     /locus_tag="KRN00_002634"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBH1828493.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(8123..9673)
                     /locus_tag="KRN00_002635"
     CDS             complement(8123..9673)
                     /locus_tag="KRN00_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBH1828494.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(9767..10033)
                     /locus_tag="KRN00_002636"
     CDS             complement(9767..10033)
                     /locus_tag="KRN00_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBH1828495.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(10181..11041)
                     /gene="yabG"
                     /locus_tag="KRN00_002637"
     CDS             complement(10181..11041)
                     /gene="yabG"
                     /locus_tag="KRN00_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBH1828496.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(11125..12063)
                     /locus_tag="KRN00_002638"
     CDS             complement(11125..12063)
                     /locus_tag="KRN00_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBH1828497.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(12173..12334)
                     /locus_tag="KRN00_002639"
     CDS             complement(12173..12334)
                     /locus_tag="KRN00_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828498.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(12344..12841)
                     /locus_tag="KRN00_002640"
     CDS             complement(12344..12841)
                     /locus_tag="KRN00_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBH1828499.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKAYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(12956..13666)
                     /locus_tag="KRN00_002641"
     CDS             complement(12956..13666)
                     /locus_tag="KRN00_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBH1828500.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(13842..14372)
                     /locus_tag="KRN00_002642"
     CDS             complement(13842..14372)
                     /locus_tag="KRN00_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828501.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(14389..14619)
                     /locus_tag="KRN00_002643"
     CDS             complement(14389..14619)
                     /locus_tag="KRN00_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828502.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(14634..16028)
                     /locus_tag="KRN00_002644"
     CDS             complement(14634..16028)
                     /locus_tag="KRN00_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBH1828503.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(16154..17407)
                     /locus_tag="KRN00_002645"
     CDS             complement(16154..17407)
                     /locus_tag="KRN00_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1828504.1"
                     /translation="MESKNNVKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALALS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(17458..18612)
                     /locus_tag="KRN00_002646"
     CDS             complement(17458..18612)
                     /locus_tag="KRN00_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1828505.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
BASE COUNT         5850 a         3614 c         1857 g         7604 t
ORIGIN      
        1 cttattaatt taatattata ctttcagttt tagtatttaa tccacatcag ataataatct
       61 taaaatgacc aaggtcttaa aactatttat ctttatcaga tttatcttct aaatttttat
      121 ttatatcaat aacattgttt ctttcttctt catctttttc taattttata gttaattgtt
      181 cttcaacttc tttagaagaa ttttcctctg taactgcatt ttcaatttca ttcagaggta
      241 actctttatt aaatgctttt acaaattgtt ctgcatctaa agtttcatat ataagtaaag
      301 cttgtgctac atactctaat ctatccatat tttcttgtaa tatacttctt gtcttatcat
      361 atgcaccatc aactatacgc tttgtttctt ggtctatctc aaaagcaact tcttcagaat
      421 aatttctctt acttgaaaaa ctattaccta ggaatacttc atcatcactg tcaaatgaca
      481 ttggaccaag tttagaactc attccatact ttgttaccat acttcttgca gtagctgtaa
      541 ctctttctaa gtcatttgaa gcacctgtag atacatcctt aagtactagc tcttctgcta
      601 ctctaccacc aagtaaaact acaatatttt ctttcatttc attttttgta gcatagaact
      661 tatcttcaac aggaagttgc attgtaaacc ctccagctct tcctcttgga actattgtaa
      721 cttgatgaac aggacttact tcttcaagta catgggcaca aactgcatgc cctccttcat
      781 ggtatgctgt aagtcttctt tctttctcac ttattacttt cgatttttta gccacacctg
      841 ctataacctt tgttatagct tcttctatag tttccatctt aattttcttt tctctttttc
      901 tagctgttaa tattgcagcc tcattcatta agttctctat atcagcagga gtaaatcctg
      961 gtgttcttct agccaagaca tccattttta catcatcact taatggttta tttcttgagt
     1021 gaactttaaa tatagcctct ctacctttta catctggtgt accaacaaca acttgtctgt
     1081 caaatcttcc tggtctaagt aaagctgggt caagtatatc tggtctattt gtagctgcca
     1141 tgattattat accttgattt accccaaatc catccatttc aactagaagt tgattaagag
     1201 tttgctctct ttcatcatga cctccaccaa gacctgcacc tctttttcta ccaactgcat
     1261 caatttcatc tatgaatatg atagctggag cacttttctt agcctgttca aataaatctc
     1321 ttactcttga agcaccaacc ccaacaaaca tctcaacgaa atcagaacca cttatactga
     1381 aaaagggaac tcctgcttct cctgcaactg ctcttgatag atatgtttta ccagttccag
     1441 gaggtcctac cataagcatt ccttttggta ttcttgcacc caattcaata tatttcttag
     1501 gattctttaa gaaatctact acctcctgca aatcttcttt ttcctcatct agtccagcta
     1561 catctttaaa tgtaactcta gttttttcat catctttatg aaccttagct tttgatttgc
     1621 caaaactcat aacctttccg cctccacctt gagactgatt cataaacacg aaccaaataa
     1681 tcaccatgaa gaatattaac agtaatgtag gcaacatttc gacaaaccaa ggtgtagatg
     1741 gcttagcttc accaccaaaa gttagtttcc cagccttagc ttggtctaac acctcatctg
     1801 caagtttatt tcccatcact tctgttggaa catatgactt aaactttgta tttgtatctt
     1861 ttatagtacc ttctacagaa gtttgattta caaagtataa tcttgatata ttctcatctg
     1921 ttaattctct atatacttca gagaatttta aatcttttat tttttctgta ggcttacctg
     1981 agaattgaac tatacctact ataattataa aaacaagtag ataaaaacct gctcctttta
     2041 gcaacttatt caatatagaa gccctccttt catacattgc tttgccctat aatttgttaa
     2101 aattaatttt taatacttct tttgtgtttt catcaatttt ataattttca ctgattttat
     2161 aatctccaac acatattatt ccttcactat ctgtgattat aggaatttta catctttctt
     2221 ctcttgggat ttttaaatct atgaataaat ctttcacttt tttacttccc atagcaagct
     2281 ttatcttatc accttgcctt ctgcttctta ttactatacc cccttttacc ttattaaaat
     2341 caaacccttt agatgaattg tctaatttca tactcttata cctatctatg ctcattactt
     2401 gggtctcaat aatttgtttt aattctttta ttttaataaa cccattacta ggtacattgt
     2461 aataaaattc aatttcctca ttaacaattt cctcattcgt taatattata ctgccttttt
     2521 ttctataaac aaatatattt cttggaagag ttaacatttt atttactttt gaattatctt
     2581 ctaaagacat tatatcttct atatgtcttt ggtcaacaaa attagtatct cctagtatat
     2641 gttttatgga atttctaaga actctaactt tgatagcatc atgtaagcaa acaaaatcgt
     2701 ctaaatttat ctctacaaag cctttttctt ttatatttga aacttctcta aatttagctt
     2761 ctgcctcttt ctcaatataa tcgttatcac tttttaaact attgctcatc ctcactatag
     2821 attctattac atttgaatta aaattatcct tcatatatgg taaaaggtct aaccttatct
     2881 tatttctagt gtatatattt tctaaatttg ttttatctat cctcggattt aaattataag
     2941 cttcacaata ctcctctatc tcatttcttt ccacgtctaa tatgggtcta attatgcaat
     3001 tatctctaat ataatcaatt ccctttaagc cttttaaacc tgttcctctc atgatacgca
     3061 tcataaccgt ttcggcttgg tcattgagat tatgacctat tgctatttta ttggctttaa
     3121 tcttatcctt aatttcataa aacatttcat atcttagctt ccttgctcct tcttctaatg
     3181 ataatccctc attttcacaa tattttggta cattaataga ctttacaaag aatataattc
     3241 ccatatcctc acaaagttta gatacatata atgcatcttt ttgagcttct atccctctta
     3301 tttgatggtt taaatgtgct gcatatattt ctatattaaa atcttttttt aatctattta
     3361 gtacatgcaa taaacaaact gaatcaggtc ctccagaaag acctaaaact attttatcgc
     3421 ctttttgtat taaattatgt ttatttatag tacttagtac cttatcaaat atcatattta
     3481 tccctcttac acttagtttt attcactttt aagtatactt tctataaaaa aacgctaaac
     3541 ccttgtatca attttaagaa attaaagttt aatataaata taataatacc aaataaatta
     3601 aataaaaggt agttttttca ctacctttat aaaatttctg gaaaatagcc atagttatta
     3661 tttagtacct atgtatatat ctattttatt cctacctaaa aataaatctt gtacctttat
     3721 attatagtct attttcaatt ttatgtgttc cccttcttgt atatttatat ctaattctct
     3781 tgtatcaata tcaattaata aagtaccttg tggggtcaca tactttgtag tactactttc
     3841 tccacattta aacagcattg ttgagttaat agcaccaaac tttttgatac taacttgatt
     3901 tttaagtatc tttatagtat tagttatttc tatatcttct tctttttcct tgtaaataac
     3961 atatattcca tcatttttat aaaaaatttt accaaaggca gtcatctcta tggtgtccat
     4021 atttcctttt tcatcatatt gtctagtatt tatacttatt tttacactca acgatttttc
     4081 ctccatagat tcttcatata aactagtatt tttgtatttc tactttttga atcttatcaa
     4141 tttttttctt taagaactct cttgctatat ctgaaaattt ttcaggtata tctgatacat
     4201 aatattgata agttccatga atttctgtat tgtttataat attttgcacc tctaaaatct
     4261 tttttaaatc ctttgcagtc tctttagctg gattaacaag ttttatatgc tctccaactt
     4321 cttcacctat tgttctcttt aaaataggat aatgagtaca tcctaacact aaagaatcta
     4381 tatttttttc tttcaattct tgtaaatata tctttgctgt cagtttagcc acttctgtat
     4441 ttgcccatcc ttcttcaaca ataggcacaa ataaaggaca tgctttatta acaatttcta
     4501 tactctcatc tattttagat atttccaagt tgtatgcttt tgaacttata gttccttcag
     4561 ttcctattat tcctacaatt ttgttttttg tagaacttac agctgttcta gctcctgctt
     4621 ctataactcc aattatcggt atatcatatt tttcttgagc ttcttttaag cttcttgcag
     4681 tagcagtgtt acatgctata actatagctt ttacaccttt tgtttttaaa aagtttatag
     4741 cttgaaaagt atatttaatt atagtttctt tggatcttga accatatggt attctggcag
     4801 tatctccaaa gtatattata tcctcatttg gtaatatctt cattatctct tttagaactg
     4861 ttaatccacc taatcccgaa tcaaaaactc ctattggttt attgttcatc tttatacaac
     4921 acctacttta catttttgtg tttaacaaca acttatttat cgctaaaatt tatatttata
     4981 ttcataatta atatattatt acctaaatga ttattatagt ttattttaca caaaaaataa
     5041 aggagctatc ttaaattaga aaataatttc tacaaaaaga caactccttt cactacttaa
     5101 aaatttaaat ttattttgca aacacatgat ttcctattct catataagga ttcaatctat
     5161 ttatccattt gcaagtggct atttctggat tccaaaaata tactgcttta ttagttgggt
     5221 cagttccata aagagcttcc tgagctgctt tacgtgctga gtctgttggt gccatcttta
     5281 ttgaaccatc aagcacaact gagaaagcat ttttttgata tatgacttct tctattgtgt
     5341 ctggaaatct agggtccaat actctattta ttactacagc tgctacagca acctgtccct
     5401 catagctttc tcctctagct tctcctgcaa ccaacttaga taataacatc aagtcattat
     5461 cagataaatt tattacttct ttctttgcta tatttttttc ttgtttgttt actttcttaa
     5521 tattttctgt tggttcatat gcaaatacct ctttaatagg cataaatata aaagtcaaag
     5581 ctaatagtgt agccatcagt ttactccacc tgtccatgat taaaaccact ccttacattc
     5641 ttatttttaa aattttttct ctaaatcctt gactacttca agtactttaa acttaatttt
     5701 tactctactt gttttttttg gtgtatcttg ttttattaac ttatattctt tatcagttaa
     5761 aacttccttc aacttatcat ctgtagattt atctatcact ccattagatt catcaacaaa
     5821 acatagtgga gggaacataa cacaccacca gttttttcct tcacctttcc caataataat
     5881 ctttaatgct ttatattcac cagctggaag aactatatta gaatattgtt tagtagggaa
     5941 attgctatat tgtataccta cctttacact gtaattatat ccatttttaa gaataatatt
     6001 tttacttatt tcttccagac tactatattc cttttttata atagcttcac tttcttttat
     6061 actttttgaa ttttgaagct ttggctgtaa atattttatt acttcatctc taacttttag
     6121 tttaagttct tggtcttcat ctgtattgct gtttgctata acatgaaatc ttattaattt
     6181 atctttataa tcttttgata tattgtctac tttttttacc tcaccattta ttactattgt
     6241 cattattgat atgactgata taagacttaa tattaatagt cccaatctaa tcttaatttt
     6301 tctcattgaa aattccccct caagataaat ttatatcatc aattatgtcc aattaaattt
     6361 aatttattca taatattttt taatactaat aaaaaaagct atcttaaaat gattacaatc
     6421 attttaaaat agctttttaa accttatatt ttataagtct ttactaatca tagccttatc
     6481 tatcataaac tgctctgctt tttctatatg ctctgtagca tacttcttgg atagctcact
     6541 atcaccttta attatagcat caagtaaata tttatgctct tcaacaatat tatgtgatgt
     6601 atcataagca gacatatagg taactctaaa tctatatact tgttcccaca atgagtttat
     6661 taattggatt aattttttat tattagttgc tttaaatata cattcatgaa attctacatc
     6721 aagttttaat aacgcatcta catcggattc caaagtgctt tttttaaatt cttctgatat
     6781 atctttaagc tttttaatat cttcatcact aattctttca gcggcaagat atgctgctaa
     6841 gccttctagg cttgctctta cttctaatac atccataata tcctttaatg acatatttgc
     6901 cacatacgca ccttttctag gcaacataac gactaaacct tctaattcaa gctttcttat
     6961 tgcctctctc actggagtcc tacttactcc taattgttct gctagttgca cttccattag
     7021 cctttgacca ggctttaatt ttccttctaa gattgcttct cttaaattct caaagactac
     7081 atctcttaat ggcttgtaat tatccaagtt cagtttagtt aaattctcca caaatttcaa
     7141 cccctttttg actgctatta acaacataca cctgtttata tttttttaat aattcttttt
     7201 ttccaattag agcatcttct ttatttttaa atagtccaaa aactgtagga ccacttccac
     7261 tcatcataga acctaaagca ttatttttca tcattacttg ttttatatca cttatttctt
     7321 tgtgtttacc tatagtaaca ttttcaagaa tatttaccat gctttctgat acagctttta
     7381 tatcttcaga ttttaaacac tctatcaaat atttattatt tggtcttttt ttaatattat
     7441 tcaaatctaa tccttgataa acttctttag tagaaacgaa taagtctggt ttgcatatca
     7501 atatatttgt atcacatggt aaacctttga tgtttgttag cttttctcca ataccttgag
     7561 ctaaggcagg tcttcctgat atacaaaaag gaacatctgc gcccaaatta agtcctattt
     7621 cttttaattc atcttcagat aatctaagtt cccataggtg atttaaacct actaatactg
     7681 cggctgcatt agaacttcct ccagccatcc ctgctgctac aggaatattt ttttctatga
     7741 atatttctac accttttttt atataaaatt tatttttaag tattttggca gctttataaa
     7801 caatattatc ttcatctaaa ggaatatcta aactagtgct ttttaccttt atttcatctt
     7861 cgtctaattc ttttatcttt actatatcgt ataaatctat cgtttgcatt atcatttcaa
     7921 caaaatgata accgtcttgc ctttttccca agacatcaat ggataaattt atttttgctc
     7981 tactctttag tcttataaaa tccattctat cctccttgtt taaagaataa tgcatcacta
     8041 acaataatat tatactacaa aaaataaaat aatagggtat tataataccc tattatactt
     8101 aattacttta aattttttaa tattaatcta ctaatacgac ttttttttct aaaataagac
     8161 acttcccagg cttaattggt tcatcaagtt ttatatcatt aagttctgca atttcatttt
     8221 ctgttgtatt gtattttttt gctatattcc agaaagtatc tccttctttg catatatata
     8281 cgattatgct aggagcttta gataaatcat atacaccttg gtcttctccc ttgataataa
     8341 aattttctgc tttcttatct aatgcttcag taaatctctt aattttgata atcaagtcta
     8401 tctggtccct attcaaatca acttcgactt tatcaataca tgctgtatta aacacagatg
     8461 ctgtatcagt tagattatcc atttctatat catgttcaaa tggaatttcc tcactaattt
     8521 tataaaccaa ttttaaacct tcaactggga caaataaaat ttcaactttt atgattcctt
     8581 gtataatgct tttatttcct tcaatataac tattttctat agacatggtt ggacaaacgc
     8641 ttacaatatc ttttatttgt atatcatcat tatcatttct tatgccttct ctaaccataa
     8701 atgtttcttc actacgtctt aaagtcttat ttaattgaat aggtttgtgg tcaaatttta
     8761 ttatcttttg aggcgaatat gcatcttgta atacttctct tgtaacttca tctgtaactt
     8821 ttaccttaca acaagccata caatctattt ctaaaagacc tgtgttgctt tcactatttt
     8881 gcttgaaaat atgattaaaa tctgacatag acaacaatac ttcttcagtc ataccatcac
     8941 taactccagg gacttctaca aattgagtaa actcaatacc tactctatcc aactctacaa
     9001 gttcaccctc atatgtacaa gctaacggat ttatttctaa tactccacca ataataactt
     9061 tattgtcagt cactctactt tcttttactt taacacatgg atttaaactt attatagatt
     9121 gaatttcctc tgtgtttatt gttatagtat ctcttataga actttctgct ttttctattc
     9181 caactatatc ttgaaaacaa atttcctttc tgtgcttttg tatgccttcc acttgcgcca
     9241 catcttttac aatgtctaac ctttgctttt caaacaaact tccccttata ttcataagag
     9301 ctcctacttt aatctttctc tcattcatta tagtacaatc catatgctct acttctgaaa
     9361 ataacatgta ttccatatct tgaataacat tgtctttttc tattacttcg tttatatcta
     9421 cttttccgtc tacattagaa atagtatttt tatcatctgc aatatagatt acattataat
     9481 taaaactacc tctgcaaagt atcttcccat ctgccatttc aattttttta agtgatatgt
     9541 atccttctgt ttttacaatt tcatatacat ctaatttttt gtctggcaca actgcctccg
     9601 cttcaatgaa tgtttgaaat tttccaaagt ctattctatt gtcaacttta attacatctt
     9661 taattaattc catagtctac ctccttaagt attataaaaa tatcacacta tatttatatt
     9721 taaggagcaa aaaaaaaatt acacctattt ttaaataggt ataattttaa cttatttgta
     9781 atttatcttg atctctaaaa acttgcaact ttacattaga tgttaataaa tctgagtaac
     9841 tataagatac tctaggatat ccattacttt catcatctaa ctttataaca aacacgcttg
     9901 gataaacttt ttctagtata ccctcttttg taataatctg ctttcttcct ttattagctt
     9961 tcaacaatat tttctttcct atatgtctct ctaagcttac tcttatctta tctagagttt
    10021 gaacagtagc cacaatatca ccttctttaa cgtttatatg tttacataat atcacatata
    10081 aacatttttg tcaaatgttt aaactaatta ttttatatat tttttgcaaa aatgtcaata
    10141 ctatttttga agatatacag tataattatg ttaatttttg ctaatgtaat attgtttttg
    10201 gcattgccca tctaaatttt cctcttgttt cagaaccacc aattccctta acacctgtaa
    10261 tagtctgctc tataacctca tcaataggaa ctactacatc aattcttgaa caagcaattt
    10321 tctccactat aaaaacaggg tctaatgcat gtatcattat tcttccaggc gaacttgcat
    10381 agtttgctcc tgcacttatt attttttcat aatttgattg gcatgctcct gcgaatatga
    10441 caagattatc caaatttggt tgccatttac gtgcttcttt tactgtttta acaaaatttg
    10501 aagagtttct atagttactc atatcttcta tatctcctct ttttattgtc attgcatcat
    10561 gacctgttat tactagtata tccggattat atttttctag tagtgctctt acttctttat
    10621 actgattttg ctctgaaaca gctacaccta ctgcaggtat tccaagttga gcatatacat
    10681 ccaagcaaat ttttaaatat tctttatctc catctatctg tagtactttt ccaggcattc
    10741 catatgtgtt aggatttaat tgaagttttg gaactgctct agtcattctt ttttgtcttt
    10801 ctttagcttt tcttactgac ttatataata aattttctac atttttatct attaatatat
    10861 cttttatatc aggtgctttt actaattcta ggtcatcaat ataagcatct gctattactc
    10921 taaatgcaat tccctttagt atagctattt tctcattatt ttcatctaca ccaaaagaga
    10981 ctattttaaa tactatatct ttgttatgtg actttctagc tacaatgtct cctaccttca
    11041 tagttaaacc tccaataaat ttttatctta gtttatacta tgttcgatat aaaactttgt
    11101 ttcctaatgt caaaaaaaca tttcttataa tacttctttt atcactctta aagcattttt
    11161 atagtatatc ttttctatat catcttcact aaacccttct ttttttagag gttcatacag
    11221 tttacccatc tgagatatat cttcaatctc aacttttgaa tctattccat caaaatctga
    11281 ccctagagat acaacatcta ttcctccaac atttacaata tgttttatgt gtctaaccat
    11341 atcttcaagt ttactttcac ttttatcact taaaaataag tggaagaagt ttatacctgt
    11401 aactccacct ttatttgcta atactttaat catatcatca gttaaatttc tagaatgatt
    11461 catcattgct cttgaattag aatgtgtagc aattattggt ttagaagaaa tctttgcaat
    11521 ttcataaaat ccaccatctg aaatatgaga aacatcaacc aacattccca attcattcat
    11581 cttatgtacc acttctcttc caaaatcagt aagccctttt tctctatatt ctactttatt
    11641 atgaggaaag ctcaattcat tcacatgatt ccaacttatt gtcatcattc taacccctaa
    11701 gtcgtaaaat ttctttaaat tttctaattt accttcaagt actgcacctt cttcaataga
    11761 taaaagagct gtaagtttac cttctgattg gtttttcata atttcttcat agttagtagc
    11821 taaagctatt tcatcactat tttttttcat ttcctcatga aatttatttg ccatactcat
    11881 gcaataatca aaaggatgtt ttacttcttc agtatcaaca aaaagagcaa atgtttgagc
    11941 taatgaatcc ccctttttca atctgtctat atcaacagaa tatttattag acttaagttc
    12001 acttgtttct acattttcca ttaattttgc tatagtatca caatgtaaat caataaattt
    12061 catatttata ccccctgtat attttatatt tatatctaaa aatagaaata gttgtcctta
    12121 tagacaacta ttgacaacta ttttttaata ttctttttaa tattacttaa tcttattctt
    12181 cttttaagtt aggtattact tttttaactt cttcaatttg atgccatgtt ttatctatat
    12241 tattttcact aatatatttt tttaaatcag ttaaagatgt aaaatcttta actgataaat
    12301 tgtcatcatc atctgcaaat cttaaaataa acatgagact cccttacttt ccacaacatt
    12361 tcttatattt ttttccgctt ccacatgggc atgaatcatt tcttcctatt tttgcttctt
    12421 taactattgt tttagacttc ttataagcct ttattatttc ttttctttgg tctgctggta
    12481 gtatatcttc ccaaccttgt aaattatata gccaatgagc ctcaacagtt accatattgt
    12541 tatataattt ttcccaatct atttttatag aaacttcttt atcagcttct acttcttcta
    12601 aaactatatc ttcttttaag ctttcactta ttccatctat gaatcccatg aaaaattcat
    12661 tagtagttcc aaatttttca gccaattcac ttactttacc ttcaacaaca tccattttat
    12721 tatttaatat ttcattgtat attccagctt caactttcaa atattcttcc cagaatttta
    12781 cttctgcttc ttgactttca tgattatcac ttaaatttct ccattcagta tataaactca
    12841 tactttttcc tcctaagtat acctatattt ttatagtttt tatagtataa aatcttttag
    12901 ttagattgga agtttcttct ttttgattat accatattct atttaaagtt aactcttata
    12961 ttatatcata attaaacaat tcttttaata cttttatagc atactcttgg tttataaaat
    13021 aagggcttgt cgcaattgtt attactttgg cttttttaat taagtttttt atcttgtaaa
    13081 atttgagttc aaatggtata tagtccatat cacttgaaaa tatatccaaa tctatgtcaa
    13141 gaacaaactc tgattctact tctaaatcaa atccatatag actatctatt attattaatt
    13201 ctgaaaatat gttatatttt aaagcaggtt ttataaaact tcctacattt aaaacttcat
    13261 ttgtatatct aaatacatct tttagattat ttacatctac atcatagttc tcaggttctc
    13321 tagtatcctt atgttggtct acatgcacta acttgcatcc ttttgtaaac tcacccttta
    13381 acaaagattt tgcccaaaaa taaaatgcat ggttatgatt gtcaaacaca tatatctttt
    13441 tatttcccag gacatattcg accatattct ccaatccttt tgcttttatt tccttatttt
    13501 catctacttc attaaatact acctcattgc ctaaccttac atcatttaat gtaccattta
    13561 taagttttgg aacgtatatg ctcttatttt ctcttttatc atatgaaaat acattatttc
    13621 ctactggttt ttctatataa aatccactat attcataatt ttccataaaa ctttatttcc
    13681 tccattgtta tataaatata taagttataa ttttaaaaat taaaatgcac ttattgtaaa
    13741 tcatatcatc tattatagaa aacatcttat ataactaaat ataatatctt ctctcaatat
    13801 gtattataca ataagtgcaa aatatattta tataaaatat actacattcc tataacaaaa
    13861 ccatcagctt caattggaag gtaactaact cttctattca actccacctt tccaaaaaac
    13921 actacccaat atggtctaaa aatactttca attttaacta tttcaatctc tgggattcct
    13981 cccataaacc tatgagttaa tctcatagcc attttatttg cctttgcttt tactcttcgt
    14041 tcgtccttat cactatactg cacaatatta caatccacat tttttacaac ttcatatgta
    14101 ggaaaatctt gtactatact accagaacct gtagaaccat tcactaaaat ttttaattca
    14161 tttatatcat tagaatatct cctattcttg aaaatggatt tcgttttgtg aattttaagt
    14221 gtgataattt taaactctat ataatgaagt ctaacttcat gagcatattt gttctttaat
    14281 attagcttac taaataaaga attttttcca cttttagcta tctctatagc ttcttctttt
    14341 gtaattctta taggtaacgc tcttatatcc ataaaatcat tctctttctt atttttttct
    14401 tgtcattttt aaaactctat atatataatc aaaaaatatt acaattacaa ctgccataac
    14461 tccatatgga attatttttc caactataat atcatttcta gtcaatatac cataaaatat
    14521 aaatcctgtt attaaaaagt acaataatac tagaaaaccg tctattccaa gccattttat
    14581 ttctaaatct ttttttacct tagacactaa tttagacata gcagtttctc cttttataga
    14641 ttattttgtg tatttaaatt ttcacctatt ctattaccaa tcatccatgc aataaatgaa
    14701 aaaggtatag ctatcacaag aggctctaac tcaaagctct gaactggaaa tattttaaaa
    14761 taaccaaaag tcactccacc aacaatcatt cctaaaatac cacccataga tgttcttctt
    14821 ccatttccaa gaagcccacc tactataggt acaaatgccg aacccatcca aatacttcct
    14881 acaaatatac atgcatcata tacattttca aatctaaatg ctacgctaag ccccataact
    14941 gctgctaaac atacacctat tctagtaaac tttactaatt gtttctgaga taactctttt
    15001 tttgtaattc ttccatatat atcatttgct aatgtagctc cagctgctag ataatagcta
    15061 tccaatgttg atattataga acctaaaatt cctattataa atattactct tattccttgt
    15121 ggtaatgtat ctaaaactaa agttatatat ccagcagctg gagccatttc tggataagta
    15181 gctcttacta taagtcctgt catagttaac accatgtcaa aacatatcca tagtgaaaaa
    15241 caagttaata aggctcttct tccaacctta ggagaatctg ctgctgaaaa tctttgataa
    15301 aaagttgggt ctgaataagc tccaaaagaa tatacaatta acatcaatgc tttcatagct
    15361 gacatacctt ttgtagggtg cataagctgt ggtgcatctt tgagtgcttc tgtaagacct
    15421 tgaaaccctc ctatttgttc aaattgacct ggcataacca tagttaaacc aaataccata
    15481 caaaaaaaca ataccatatc tgtaatggca actcccataa gcccaccaag tactgtaagt
    15541 acaacgacta ctcctaccat tattaatcct attaattctt tatctatttt ccatgctacg
    15601 ttacctatag ttcccatagc agttatttct ccaagttgtg cacaatatat aaacatcaaa
    15661 attgccccaa ttatagcaac atgcttgcca taaaaacttt ccagtaaatc aggaactgtt
    15721 atattggttc ttatatgaat ccttggacca acccacaatg ctaaaggcat tctcccaata
    15781 tgtgcagcta ttgaccaaac tgcccatgca gatattccat atatagccgc atactctaca
    15841 ctacctactg taccaactcc tccataccat gatgcaacca aagttcctac tattaaggac
    15901 catggtaaac ttcgatttcc taggtaataa ctttccatat cttttacatt tctagaaaaa
    15961 taataaccta ttcctaataa tataaatgca aatataacta taatcccatt ttcccaaaat
    16021 gttaacatat ctaatctcca cattcttata ttttaatttt taactttaat atctaaatat
    16081 gaacaactct acccatttcc ataaaaatag gtagagttat ataataatta taagtattta
    16141 agtaatcttg ttattaagca attttattgt ttaaaccttt attttctctt ttatttattt
    16201 tatttaaagc ataagtagca aatatcccta taactgcaca tactacagat aaaataaata
    16261 tatatgtata tcctgtttgt ccatatttat ctaaccaatt acctgcaata gtgtaataaa
    16321 acgcatctgg agaaaatcct ataaatgaag caaatccaac tactgctcct gtagtttcta
    16381 aagatatatt agactctgaa acagatgcaa agtatatacc tctaaatcca aataaaatta
    16441 cacttagtat tatcatgttt attacagcta tccatataaa tcctgtactc ttaggaataa
    16501 ccaagtaagc agctgtactt actgtcatta atataaatcc tacaaacatt actcttatag
    16561 atgaaccaac tttatctgtt ataacaccag caactggaga tgctcccatt tttataacat
    16621 aagttcttat tattgataaa gcagaaacta gagtcattgg cattacataa acttctgata
    16681 agtatggact taaataagtt aaacttgaga atactaaata agttgaaaat attataagac
    16741 caattagcca agcctttggc attgtaacta cttttaacaa tgacttaata cttaatcctt
    16801 catctgatgc tccactatct tttttctctt ccactaagaa aaatagaagt ataccacata
    16861 ttatagatgc tgcagaatat aaccatacta catatttgaa tcctactgtt atttcagcaa
    16921 atttaccaaa gaagtaaaga cctataaaag aaattaatgt acctgataca cctgataacc
    16981 cttcataaaa accaaatatt cttccttgct ctgactcact tccttgcatt ctaacaacct
    17041 taacagaggc tgagaagaaa gttaatattg ttgtaaatcc ccataataca aatattaaaa
    17101 gtatcatact atatgatggg aatgtagaga aataaaatcc aagtattcct gaagcaatta
    17161 aagaaaaagt tattaatttt ctaactgaga atctatctgc aaaccatcct cctataaaat
    17221 aagataccat tcctactaat ccatataaac tcaataagtt ccctatttgt gtatgactta
    17281 atgctaaagc ttgttgcatt gggtcataaa atgatgattt catatatggt aaactataca
    17341 tagctgttgt tccaaatgcc aatatgaata ttatcaaaaa tcttttaaca ttatttttgc
    17401 tttccattga ttctctctcc ttaaaatttt attgtttata atctcattca tataatttta
    17461 ttttaatttt tctattgctt gtttaaaatc atttattata tcatttgaag attctaatcc
    17521 tacagctatt cttattagat tttccccatt catttgaact aatgtatgct cttcccctaa
    17581 gcttgttgct attgttgcaa gctctaaaga attcattaat cttctactag cttggtctct
    17641 tgtcaatcca ttgataccat ccttaagttt aaatgaaact acacctccac ctaaaccatt
    17701 catttgagtt ttacaaagct catattgagg atgagatttt aatgctggat actttaccaa
    17761 ttccacattc tcttcttcct ctaaaaattc tgctactgct aatccatttt cacaatgctt
    17821 tttcatcctc atatctaacg ttttcatacc ccttaaaatc atccatgcac tcattggtgg
    17881 taaagatgct cctgtaaaac aacataaact tggccatcta actaaatcta ttaattcttt
    17941 tgaacctgct actgctcccc ctaaagtatc cccatgtcca tttataaact tagtaagact
    18001 atgtattact aaatctgcac ctaaatctat tggtctttgt acaattggtg tcccaaaagt
    18061 actatcaact atagctaagc ttttattttc atgagcaatt tctgctattg tttttatatc
    18121 tactaagtct aatgatggat ttaaaggact ttctatataa actattttag tatttggtct
    18181 cattgcttct tttacatttt gtggatttac tgcatctaca aatgtaactt caactccaaa
    18241 tttagataac aactcagaca tgaataattt agtgtgtgaa aatattccat ctgaactaac
    18301 tatatggtca ccacttttta ccaatgctaa tatagtagat gttattgccc ccatccctga
    18361 tgtactagat atggcacttt ctgcattttc aagcatagcc aacttagctt ctaactctgt
    18421 aagagtagga ttacactctc ttgtatacac atatccccat gtcatacaca actcttcaaa
    18481 atgctctact gtctttgcag caaatgttgc tgtttgacat attggtgtag ccaatgcacc
    18541 tgttgttggg tctgcactat gtccccaatg tattattttt gtctctaaat cttgattaat
    18601 attgttactc attttgattt cctcccattt tgacttattt atacaacgtt ttccctgcca
    18661 aatttcatca atttagctta gtcttaatac attttttcaa gtatactttt ttatttgtta
    18721 taatttctaa aaatatgaca cttattttgt ttttttacag ttctaattat aaactctata
    18781 gtaactatag agtcaatatg tttttgatat tttttttaca atgtttaaaa tagtcagtac
    18841 aaaaataggt atatcttaga ataactaaag tcatcctaag atatacctat ttttatatca
    18901 caatataaat aattacatat aagca
//
LOCUS       DAEQAF010000072        18911 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.075, whole genome shotgun sequence.
ACCESSION   DAEQAF010000072 DAEQAF010000000
VERSION     DAEQAF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18911
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.075"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            309..722
                     /locus_tag="KRN00_002647"
     CDS             309..722
                     /locus_tag="KRN00_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1828506.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            913..2130
                     /locus_tag="KRN00_002648"
     CDS             913..2130
                     /locus_tag="KRN00_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBH1828507.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            2292..2990
                     /locus_tag="KRN00_002649"
     CDS             2292..2990
                     /locus_tag="KRN00_002649"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBH1828508.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(3210..3827)
                     /locus_tag="KRN00_002650"
     CDS             complement(3210..3827)
                     /locus_tag="KRN00_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBH1828509.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(3954..4976)
                     /gene="argF"
                     /locus_tag="KRN00_002651"
     CDS             complement(3954..4976)
                     /gene="argF"
                     /locus_tag="KRN00_002651"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBH1828510.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLV"
     gene            complement(5085..6272)
                     /locus_tag="KRN00_002652"
     CDS             complement(5085..6272)
                     /locus_tag="KRN00_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBH1828511.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVVLKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(6302..7162)
                     /gene="argB"
                     /locus_tag="KRN00_002653"
     CDS             complement(6302..7162)
                     /gene="argB"
                     /locus_tag="KRN00_002653"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBH1828512.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKENE"
     gene            complement(7177..8394)
                     /gene="argJ"
                     /locus_tag="KRN00_002654"
     CDS             complement(7177..8394)
                     /gene="argJ"
                     /locus_tag="KRN00_002654"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBH1828513.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(8435..9469)
                     /locus_tag="KRN00_002655"
     CDS             complement(8435..9469)
                     /locus_tag="KRN00_002655"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBH1828514.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(9723..9936)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10240..11331)
                     /gene="ytvI"
                     /locus_tag="KRN00_002656"
     CDS             complement(10240..11331)
                     /gene="ytvI"
                     /locus_tag="KRN00_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBH1828515.1"
                     /translation="MNEQDHTSYQNKQRFLINFCYLVVILGLLMLLGKYAFSVLLPFV
                     FAFLIASLLNKPVLYISEKLLIKRGIVATISVFLFFLIAGIIVSVIGTYLIYGIKEIF
                     HFLPTMFEELVIPLTETVIKEVELFSGSFNFSFIELIEANMPVLMNEMSVFIVSLSNN
                     IVSGITDIVSSVPLLFMKTIITIVASIFIAIDYPTIKRFIVLQIPKNKSYLLAEAKAF
                     TIDTIIKCGFSYLLIFAITFSELYVGFAIINISYAEIIALFIALLDILPVLGTGSILI
                     PWCIISLFLGDYSMALGIALLYIVITIIRNIIEPKLVGKHMELHPVLALASMLTGLHF
                     FGFIGLFGIPLLIAFLKKLNDKEIIHILH"
     gene            complement(11346..12737)
                     /locus_tag="KRN00_002657"
     CDS             complement(11346..12737)
                     /locus_tag="KRN00_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HBH1828516.1"
                     /translation="MKRRLAGEWEPIKGVMLAWPPFLPHKYIVDLTQNYSVYMCVPNK
                     EEIEIAKYYLSKWGGNLKNLIFCIAPQGFDTPWVRDWGMHPIFDENGKLFLAGAEYKM
                     STPFVSINKPEIMFDCEHNLLTTNSYEQKEDQSQELIAKQIGLPFMKLPYALTGGNLM
                     SDGFNKLMSMHILQTENRAKGISDEEFFSMVARDTGMNEYYIFSNFADYGLQHIDCYL
                     KIIDEETLLVSRTPKEHYLYERYEKILEEVKKVETRYGRPFKIFRIDIVPFQKDSDEL
                     TAYVNSVILNSRVYVPMYGIEQDKIAIKQWQNALPGYEIKGYEFDFEKEPDIIKNRTG
                     YVRTGWGNEDVIHCRTRAIWDENMLYISVKRLEEIVSENDALEVTIQIVDYSKAGLDY
                     ENCRLFYRYYGFQTWESIRLEETTEAEIFFANMIGKSGDMIEYFVQAKSCSGMCETMP
                     PVAPKGTYKVTIK"
     gene            complement(12756..13295)
                     /locus_tag="KRN00_002658"
     CDS             complement(12756..13295)
                     /locus_tag="KRN00_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1828517.1"
                     /translation="MSLTIQKVTSYFKDLEKFEELNNEAFPDEERMSIQEMLNLVQSK
                     KIEVSALYDKQQFIGFYVLVIENHIGYILFLAISPEQRSKGYGGKALSLMKKQYPNCQ
                     IVLDMETIEDSAPNLQQRILRKQFYLQNGFYETEYIMEYKGLEMEVLCNQKTFQKNEF
                     ETLLKNLKIREIPFHLWKK"
     gene            complement(13316..14641)
                     /locus_tag="KRN00_002659"
     CDS             complement(13316..14641)
                     /locus_tag="KRN00_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1828518.1"
                     /translation="MIQLSDNFNYKRLLKFTFPTIIMLVISSIYGVVDGYFVSNFVGK
                     TAFTAVNFIMPFLLILGCVGFLFGTGGGALIAKTMGEGKKEEANEQFSLLIVTSAGCG
                     IILAVLGIVTMPWIASAMGADGQLLTDSILYGCVVIIAIPAYILQCEFQCLFATAEKP
                     KLGLYVAIMAGITNIVLDALFITVFKWGLVGAALATAIGQYVGGIIPLLYFSRQNNSL
                     LKFKKPKFDCDVLKKTVANGSSELMTNVSTSVVSMLYNAQLLKYAGEDGVASYGVLLY
                     VALLFQAVFIGYSVGTAPIISYHYGAKNYDELKNLRKRSLIVIICFAVFMFIIGEFLS
                     KPIAFIFVGYDNNLMEMTLRAFMIYSFSFLFSGFGVFGSSFFTALNDGLTSALIAFMR
                     ILVFQVVSVLIFPIFWGVNGIWFSIVGAEILATIMTAFFIIRKQKKYHY"
     gene            complement(14638..15261)
                     /locus_tag="KRN00_002660"
     CDS             complement(14638..15261)
                     /locus_tag="KRN00_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HBH1828519.1"
                     /translation="MKIITISREFGSGGRELGKQLADILNFDYYDKEIITAIARKKKI
                     DENYVSYILENHGWRNVPLTMCTSFTNILSMQSMKTDLLIEQSNVINQIASTGKDCVI
                     VGRNADILLKKYQPFNVFVCANMNFKIQRCIEKKLNNEHISKKELERKIREIDKNRAR
                     SREFFTSSLWGNQTSYHIIVNTSEWNIKHLSYAIANFSEYWFRRYEQ"
     gene            15353..16162
                     /locus_tag="KRN00_002661"
     CDS             15353..16162
                     /locus_tag="KRN00_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1828520.1"
                     /translation="MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYY
                     TIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMC
                     SMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
                     LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSY
                     DSLYKTYQNMKNQLEEQGYHIVGNIYEEDLIDYLSEHNAENYIQKISMQVI"
     gene            16596..16958
                     /locus_tag="KRN00_002662"
     CDS             16596..16958
                     /locus_tag="KRN00_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1828521.1"
                     /translation="MEIDYKAIGQRIKIARIKKGITQESVANIINMTPSHMSNVETGK
                     TKVSLPTLIAIANALSVSVDTLLCDNVLSSKVIFEKEAKDIFSDCDEYEIRSLVELLK
                     SAKTVIRKDREIRKQFEK"
     gene            complement(17095..17214)
                     /locus_tag="KRN00_002663"
                     /pseudo
     CDS             complement(17095..17214)
                     /locus_tag="KRN00_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(17308..17865)
                     /locus_tag="KRN00_002664"
     CDS             complement(17308..17865)
                     /locus_tag="KRN00_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1828522.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSFL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            18123..18821
                     /locus_tag="KRN00_002665"
     CDS             18123..18821
                     /locus_tag="KRN00_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1828523.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEISVVEKFVEKFNCNLTIVENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
BASE COUNT         6570 a         3144 c         2215 g         6982 t
ORIGIN      
        1 aactactaat gatattattg aacatagcaa tagaataaca tctaaaatag tttttatgta
       61 ttaaattaac ttattttaat attcaacaat ttaggtttac taaatttatt gatgatttct
      121 ttttatataa cttaaactac atttttattt aaaaaaattt aatatcaaca atataaaatt
      181 aagaataagt attattagtt tgacattagc ataaatgcct attagaataa tgttaaacta
      241 tattctttct actgatttta ttaaaaaata ccaatataca aaagattata caaggagaaa
      301 gttcaaatat ggaattagaa attacagaaa aaatagaaaa acaagatgaa gatactattt
      361 ttcaaggatt attaaaatat aatcttgcta gacttgaaga taaaaaccca gtggatttag
      421 gaatatatat tcgagataaa gcaggtaaaa ttgttgcagg ttttataggt gttactcatg
      481 gtaattggct ttctataaaa tacttatggg ttagtgagaa gcttagatat aaaggtactg
      541 gaagtcaact tttatataag gctgaaaaaa ttgctaaaga acgaggttgt aaatatgttt
      601 ttttagatac attcagtttt caagcaccta aattttatga gaaatttgga taccataaag
      661 tattttcact tgaaaattat cctctaactg gaaagagata ttattataga aaaatactat
      721 aataataaaa atcatatttc atatttttaa attaaaactt ctgctcttcg tctacagact
      781 ttatgttttt atatcattat taatactaaa atagtatttt actatacata caaaattatt
      841 tgaaagttca aaaattataa gtataaaagc taatcttagc ttaaataaaa attatatttt
      901 taggaggtaa atatgttagg aaaaaaatgt atggattatc tacaaacatt aggaaaaata
      961 agttcaacaa caaatggtct tacaagactt atcttgactc aagaacataa aaaatctatt
     1021 gatttaatta gttcatggat ggaaggttta aatcttgata ttgaaattga tgacattgga
     1081 aacgttatag gtacatataa atcaagcttt ccaaatgctc ccacattagt agttgcatct
     1141 catcaagata gtgtaaagtg tggaggtata tttgatggta tgttaggtat aatagtgcct
     1201 ctagttggtc ttgaagaagc aaaacacaat aataggtctt atcctttcaa tattaagcta
     1261 attgctttcg ctgaagagga aggaactaga tttgaaactt ctttaatggg aagtaaagtt
     1321 tttgctggta cttttaaaga ggaacttctt aaatctgttg atgaaaatgg aattacactt
     1381 gaagaagctg taacaaagtt tggatttaat acaaaaaact taacaaattt gcatcctaga
     1441 aaagatgtag atgcatattt agaatttcat atcgagcagg gtcctgtttt agaaaatgaa
     1501 tctcttcctg ctggaattgt atcaagtatt acaggattta aaagttttaa gatatcagta
     1561 aatggtaagt ctggacatgc tggtacactt ccaatgaata tgagacttga tgctggatgt
     1621 tgtgcctgtg aatgtgtatt agctatcgaa aaagtagcta aaacgactac tgatttggtt
     1681 gctactgtag gaaagatgaa tttctatcca tcttcatcaa atgtggtacc tgaaagagct
     1741 gaatttactc ttgatgtacg ctcttgttca caagaaattc ttgataattc tgtagaaaag
     1801 atatttaatg aaatatcaca tatatgtgaa aatagaaaac ttaattatac aagtgaactt
     1861 gcttttgaaa atgttcctgt accatgttct aataaaataa caaaaatcat agaaaaaagt
     1921 tttatagatt taaatcttaa tcctttttat atttatagtg gtgctggcca tgatgctcag
     1981 gaaatggata atataactga tattggtatg gtatttataa gatgcgctgg gggcgtaagt
     2041 cataatccta atgaaagtgt ttctgtagat gacctggata ctgctgtaaa aatattttta
     2101 aaaatactag ataatcttga tttaaaataa ttcttatata agaaagtata ttaaaatata
     2161 taatctaaaa aatcacttta tatttatatt atataagtgt acaatataat ctattataaa
     2221 atataatttt atgcttttat agatttttat tttatacata aatatattta tatataaagg
     2281 agataatttt tatgaatgaa aaattaattg gtattttggc tggaatgggt ccaaggtcaa
     2341 cagccccttt tgttgattta attattgatg agtgtcaatc tcaatatgga gcaaaatatg
     2401 atgatgaatt tccaaagatg atgatatatt cattacctac cccattttat attgaccgtc
     2461 caataaatca tgaccttatg aaagaaacta taattgatgg attacaaaag cttgaatcaa
     2521 ctggtgtaaa ttttattgca atgccatgca attcagcaca tatatacttt aaagaattaa
     2581 aagagtctat taatatacca atattaaata ttgtagaaga aacagttaaa aaattaccta
     2641 ctatctcaca aaaagtaact cttttttcga ctagttcaac ttttgagtct acaatttacc
     2701 agaatggtat aatacataat ggacatgaat ttatatttaa agatgaatgg caaataaaat
     2761 taaacaatct tattcaaaat ataaaaatgg ataaagaaaa tccacacaat attgatattt
     2821 ggaataaact tattgaagat gttaaaaatg aatctataga aaatatagta attgcttgta
     2881 ctgatttaaa tgtagtttta gaaaaatcat atccttcaat aaatattgtt gattcatcaa
     2941 aatgcttggc tgaatcagtt gtcaataaat atctaaaatt agttaaataa atttttcatg
     3001 cactatatta taaaaaatat atgttataag tttatcttaa atagtataga cttataacat
     3061 atatcatagt ttcttgacaa tatagaaatt aaccatgtat ttcattatat taataaaaag
     3121 gataccaaaa atggtatcct tcataaatat ttatatgttt atttataaaa ataatcatat
     3181 atttattact ttactacacc taaacaatat tattcaagtg tattcataga gttagaaaat
     3241 tcttgtcctg ctgtaacaag attagataac aatacatcag ctactgcatc atttactgaa
     3301 cttattatcc atttattatc ctttttagaa cattcaaact ctacattttt tgtaacataa
     3361 gtctctttaa cgcttttttg tttttctttc ataattgata ctaacatttc agttgttttc
     3421 tcatcagtta agtcttgtcc tgaaaaactc ataccaatca tctttgtaaa tgcctcagct
     3481 actatttctt gaagtaatgg tgttgaatct ataaatttac attctacttt gattgtagcc
     3541 ttatcacctt taacctcgct gtcttttatt gtatatgtga ttttagatgc attctgtttt
     3601 agataatcta aaacatattg ggcatttggg tcttttgtat ctaattcctt taatatatcc
     3661 ttatattttt cgtcattatt ttccattacc ttattcatgc cttcaaagtc aaactttttc
     3721 gcactgttaa aaaaactatc aattgtatct tctggttttg cacttgaaca tgctgttaaa
     3781 gatattgcta ataaaaaagt tgttaaagct aatatgattt ttttcatatc tcaaatcctc
     3841 cctcttaatt tgttgataca taagttattt taacatataa tgagagtttt tgaataatat
     3901 atttaaaata ttttataaat tttcattaaa gtaaagtcta tattaaaaca tatctatact
     3961 aaattattgt tcatatttac atcagtcata gtagaaacca taacagcttt tattgtatgc
     4021 attctatttt cagcttcttc aaataccttt gaatattttg aattaaatac ctcgtttgta
     4081 acctctaatt ctgataatcc gaacttttca taaatctcct gagcaacctt agtttctaaa
     4141 tcatgaaatg ctggaagaca gtgtaaaaat ataacatttt cattttcagt tttctttatc
     4201 atatccatat ttacttgata atctttaagt tgatttattc ttgcttcata ttgctcctct
     4261 tctcccatag aaacccatac atctgtatat ataacatctg cacctttaac atcatcaata
     4321 ttttcagtca acattatatc tcctttggat ttcttggcta tttccttcat ttccttaacc
     4381 aattcttcat ttggccaaag ttccttaggt gctagtgcta cgaaatgtat tcccatttta
     4441 gcacatccta tcatcagtga gtttcccata ttatttctag catcaccaac atatacaaat
     4501 ttaactttat tcaaatcttt atctacattt tcaattactg ttaaaaaatc tgccagtatt
     4561 tgtgttggat gatattcatc tgtaagtcca ttccaaacag gtacaccaga atattttgct
     4621 agactttcaa ctgtttcttg tttaaagcct ctaaattcta ttccatcata gaatcttcct
     4681 agaacttttg ctgtatctga tacagactct tttttaccca tatgacaatc atttggacct
     4741 agataagtta catgtgctcc ttcatcatga gctgctactt caaatgaaca tctagttctt
     4801 gttgatgttt tctcaaataa taaagctata ttttttcctt gtagcaaatc gccttttata
     4861 ccaacttttt tcttagtttt taaataactt gataaagtta ataaatatct aatctcttct
     4921 tttgtaaaat cctttaatgt caaaaaactc ttacctttta aacttatatt attcatatta
     4981 attcgcccct tcttataaac tttttaaatt caattaaact tgttagcact ttactttttt
     5041 atttacttct aatttttatc tttaatcaac tattttttga atatttagtt aatttctagt
     5101 aatatatctt ttaggatttc aagagcctca tctatttcct tataactgat tgttaatggt
     5161 ggtaaaaatc tcaatacatt ttttccagca gtcaaaataa gcaatccttt ttttctagct
     5221 ttctcttcta taatactaga ttcaatatta gtttcaattc ctatcattag accaatacct
     5281 tttgtcttta atacaacttt gttattaaaa ctttcaatag attttcttat ataatttcct
     5341 ttttctaata cttcattata aaaaccatct ttagatatct catctaatac aactgaagct
     5401 gccaccatag ctaataaatt acctccaaaa gttgtacctt ggtctccttt tcctagtact
     5461 tttgaaagtt ttttatttac caatactcct cctactggta ttcctgctcc caaccctttt
     5521 gctacggtaa ctatatctgg ttttacatca aaatattcat agccaaaaag tttaccagtt
     5581 cttcctatac cgcattggac ttcatcaaaa atcactacaa tatccttttc ttgacatatt
     5641 tttactattt ccaaaacata atctttttca agaacattaa ctccaccttc gccttgaatc
     5701 gcttcaagaa ttattgcaca aactgtggaa tcaagattat tttttaaatc ttcaatatta
     5761 tttctttcta tatatttaaa accttcggga agaggataaa aatacttatg gtatttgtcc
     5821 ataccagttg ccattaaaga catcattgtt ctaccatgaa aagagtcttt taaacttatg
     5881 atagttcctc taccattacc atatttgtca ctactatact ttcttgctat tttgaatgct
     5941 gtttcatttg cttctgttcc agaattacaa aaatatactt tagccattcc acttgaatta
     6001 attattttct ctcctgaata caacactggc tcattaaaat ataaatttga agtatgtaat
     6061 aatttatcta cttgctcttt tagagcattc tttaaattac tattactata cccaagagaa
     6121 gatactccat atccacttgt aaaatctatg tatttattgc cattagtatc aaaaaaacaa
     6181 cttccttcac cataatctat gacaaaattg ggttggttat atgtatctat aaaatattca
     6241 ttccattttg aaattgtatt gtcgttattc attcttattc tcccctctta aacttataat
     6301 tttattcatt ttcttttctt attaatgtac ctattccact atcagtaaat agctctgtta
     6361 ttatagaatg tggaactctt ccatccaaaa tatgtaccct atttactccg ttatttaagg
     6421 catctacgca tccctctatt ttaggtatca tacctccagt aattatacct tcttcaaata
     6481 atttatcaac atcctctaat ataacttctg ttattaatga tttttcttca tctggctctc
     6541 ttaacaaacc agggacatct gtaagaagta tcaatttatc tgcatttaac tctttagcta
     6601 tagcagaagc tgctgtgtca ccatttatat tataagtctc tccatcatct ccaacaccta
     6661 tagttgcaat tactgaaata taacctgact ttagacaaga ttctataagc tcaacattta
     6721 cttttttgat ttctcctaca aatccaagtt cataattttt atatgggtca cataaaatca
     6781 tattattatc tattccacaa agccctactg cttttccacc ttttgtatgt attttattta
     6841 ctaggtcttt attaaccttt ccagcaagta ccatttttac aatttccatg gtctcttcat
     6901 ctgtatatct aagaccattt acaaatttac tttctatatc cacttttgct agcatcttat
     6961 tgatttctgc ccctccacca tgtactaaaa ctatattgat tccaacataa ctcattaaca
     7021 caaggtcttc cataacagat tcttttagac catctttttt cattgcactt ccaccatact
     7081 taactacaat agtctttccc tgatgttttt ctatatatgg taaagcttct ataagtgtat
     7141 ttgctttttc tatattaatc attaaaatat atcctcctaa tttctataac ttccatttat
     7201 tcttacataa tcatagctta aatcacatcc ccatgcattt cctctggcat tgcccatatt
     7261 taaatctact aatatactta tttcgtcatc ttcaaggatt ttttttgctt tttcctcatt
     7321 aaaatctaat ccatttccat ttttacatac ttcaatatat cctttcatac tctcaaaaat
     7381 aatatcaact ttttccatat ctatttcttc acctgcataa cctaaagcac acagtattct
     7441 accccaattt gcgtcagctc caaatacagc tgtctttact aatgaagaag atataactgt
     7501 ttttgctaat tttactgcat gttcttcact taatgctcca tttatatagc attcaattag
     7561 ttttgtacat ccttctccat cttttgcaac aagtttagca agttctatac agacatatgt
     7621 aagtgcactc aaaaatactt gataatgttc atcttttttg tttattctat cattttttgc
     7681 ttttccattt gctagaatca ttaccatatc attagtactt gtatctccat ctacactaac
     7741 tctattaaaa cttttgtcaa cagcaatttt taaagcttct tttagcaaaa ctccatcaat
     7801 atttgcatct gtagttataa atcctaacgt tgttgccata ttaggatgta tcatgccaga
     7861 accttttgcc atacctccaa tagttatttt tttatctcca tacattattg ctactgctat
     7921 ttcttttttt ataatatcag ttgtcataat agcttctctt gctccaatat gaccttgttt
     7981 acttagatta ttcactaatt catccatatt ttcttctatt aaatctatat ttaatggctt
     8041 tcctataaca cctgtagatg caaccaaaac atcactttct ttaatattta atttatcact
     8101 ggtgaattta gccattttat aagcatttat aagtccttct tttccattaa aggtattagc
     8161 attagcacta tttactatga tagcttgtgc ctttccattt ttaatgtgtt cctgtgtaac
     8221 ataaacagga ttgcccttta ctttattttg agttactact gctgctgcat cacataaaac
     8281 atctgaataa accaaagcta aatctctttt ttctttattt tttctcaagc cacagtgaat
     8341 ccctgaagca aaaaatcctt ctgaaactgt aactccaccc tttataatct ccatatttat
     8401 cctcctaatt atatgagttt agtatttttt atttctaaaa tgatggtgca atatttttta
     8461 aacctgtatt ttcttcaata ccaaatatta tattcatgtt ttgtatagct tgacctgctg
     8521 ctcccttaat catattatct atagctgaac agattatcaa tgtatctcca ttttcatgta
     8581 atgatattac acatttattt gagaatctaa cattctttaa agaagctacc ttatctaatg
     8641 gaagaatttc tataaattct ttaaattcat aataatcagt taatttccta tgtatatcat
     8701 ttatagaaat attatcttct tttgtacaat atatagttga taagattccc ctatttactg
     8761 ggattaagtt tggtgtaaaa actacactta ctttttcttt gcaggattca cttaaatttt
     8821 gttctatttc tggagtatgt ctgtgtttcc ctattttata tgcagtgata ttttcattaa
     8881 cctccgtaaa gtgactacta atcgataatt ctctaccagc acctgtaaga cctgatttag
     8941 aatcaattat tatattatta ttttttatca atttagaact tagtaatggc atcaatggta
     9001 aagaaatact agttggataa catccaggat ttgcaattat atctgcatct tttatatctt
     9061 ctttgtatat ttcacttaat ccatatacag cttttttatg taagatttta tctataaaag
     9121 atactccata ccatttacta tatacttctt catcttttat tctaaagtca gcacctaaat
     9181 ctataacttt ctttttcgat ttaattgcct ttattacaaa cttttcacta actccatgtg
     9241 gaagggctgt aaatacaaca tcacacatat ctataacttt ttcattttct atacatatca
     9301 tgttattttt atatcctata cttggatata tatcaactat atcttttcca acatacgaat
     9361 ttgaacctat cgctgtcact tcgactttat catgattcat taataatcta atcaactctg
     9421 ccccgacata tccagttgca ccaataatac caacttttat tttattcatt ttgttccctc
     9481 catttttata ttcaaatagt cttaaaatcc tatctttcca ctttactata tgataatcat
     9541 ttgataatac gtagattaaa atactctaat taaaacaaaa aaccccttag cattataaat
     9601 actaagaggc gattttccgc ggtaccactc ttattggtaa aattacaata atcattaaaa
     9661 ctcaaattaa aaagtatcta caaaatgtac atttaaaatt aaaaaagcct cttggtcaaa
     9721 gaccaagaga cgaatataca cccgcgttac cactctaatt gataagataa tcttacccac
     9781 tctaatctct taaggcgaga ttcaccaatt accatactat tacttctggt aatctcctcc
     9841 aaagctctat tcacaataaa attcgttact aggcttccac cattcccagc tctctatcaa
     9901 ctagctttat gctactctct ttttcacagg atttcaattt attttcttat tgttttatat
     9961 gatagtttat ttttttaact ttgtcaatat aatttttaaa tttttggaaa tattttctat
    10021 ataattaatt tccagcattt tgtatctaaa ttgagttata aatatctaca gtaataggac
    10081 accatgaatt tcctgctgta atatatttta aaaaagttct ccctcttgaa tcaagtcatt
    10141 caaaagctat accttatgtc aaaattattt ttcatccagc gttttttaga aaaaacacaa
    10201 ttttctccat aaaagagaca tacatacaac tattctttcc taatgtaata tatgtatgat
    10261 ttctttgtca tttaactttt tcaaaaacgc aattaacaat ggaataccga acaacccaat
    10321 aaatccaaag aaatgtaatc ctgttagcat actggctaag gccaatacag gatgtaactc
    10381 catatgttta ccaactaatt ttggttcaat aatattcctg ataatagtaa tcacaatata
    10441 tagtagtgca attcctaatg ccattgaata atcccctaaa aataaactga taatacacca
    10501 aggtattaga atacttccag ttcctaaaac aggtagtata tctaaaagag caatgaataa
    10561 agcaattatt tcagcataag aaatattaat aatagcaaaa ccgacatata attcagaaaa
    10621 agtgatagca aaaattaaaa gataagaaaa accacattta ataatggtat caatagtaaa
    10681 cgcttttgct tctgctaaaa gataactttt atttttaggt atctgtagca ctataaatct
    10741 ctttatcgtt ggataatcaa ttgctataaa aatagaagca acgattgtaa taattgtttt
    10801 cataaatagt aatggaacag acgaaacaat atcagtaata ccagatacga tattatttga
    10861 aagagaaact atgaaaacac tcatttcatt catcaataca ggcatatttg cttctattaa
    10921 ttcaataaac gaaaaattga atgaaccaga aaatagttcg acttctttta taactgtttc
    10981 agtcaaaggt attaccaatt cctcaaacat ggttggtagg aaatgaaaaa tttcctttat
    11041 tccatatatt agatatgtac ctattacact tactattatt cctgcaatta aaaagaataa
    11101 aaaaacagat atggttgcta caatacctcg ctttattagt aatttttcac ttatgtataa
    11161 gactggttta ttcaataaac ttgctattaa aaatgcaaaa acaaaaggaa gtaatacaga
    11221 aaacgcatat ttccctaata acattagtaa gcctaatatc actaccaaat aacagaaatt
    11281 tattaaaaat ctctgcttat tttggtatga tgtatgatct tgttcattca aataaaatgc
    11341 acctcctact ttatagtaac tttatatgtg ccttttggag caacaggggg cattgtttca
    11401 cacattccag aacaactttt tgcttgcaca aaatattcaa tcatatcacc tgactttcct
    11461 atcatattgg caaaaaatat ttctgcttct gtagtttctt ctaacctaat actttcccat
    11521 gtttgaaaac catagtatcg ataaaacagt ctacaatttt cataatctaa gccagcttta
    11581 ctataatcaa ctatttgaat agtaacttct aaagcatcat tctctgaaac gatttcttct
    11641 aatcttttca cggaaatata gagcatattc tcatcccaaa ttgctcttgt cctgcaatga
    11701 ataacatctt catttcccca gccagttctc acatatcctg tacgattttt tataatatct
    11761 ggctcttttt caaaatcaaa ctcatatcct ttaatttcat atccaggcaa agcgttctgc
    11821 cattgtttta ttgcaatttt atcctgttca attccataca ttggaacata gacacgacta
    11881 tttaaaatca cagaattaac ataagcagta agttcatcac tgtccttttg aaacggaaca
    11941 atatctatac gaaagatttt gaatggacgt ccatatctgg tttctacctt ttttacttct
    12001 tctaaaattt tttcatatct ttcatacaaa tagtgttctt ttggcgttct gctcacaagt
    12061 aatgtttctt catcaattat ttttaaataa cagtcaatat gttgtaaacc ataatcagca
    12121 aaattagaaa atatataata ctcattcatt ccagtatctc ttgccaccat agaaaaaaat
    12181 tcttcgtcag aaattccttt cgcacgattt tctgtctgta aaatgtgcat agacatcaat
    12241 ttattgaaac catctgacat aagatttccg cctgttagtg cataaggtaa tttcataaat
    12301 ggcaaaccaa tctgtttcgc aatcaactct tgtgattgat cttctttttg ttcataagag
    12361 ttagtagtta ataggttatg ttcgcaatca aacatgattt ctggtttatt tatggataca
    12421 aatggtgttg acatcttata ttctgcacca gccaaaaaga gttttccgtt ttcatcaaaa
    12481 atagggtgca taccccaatc acgaacccat ggtgtatcaa atccctgtgg agcaatgcag
    12541 aaaatcaaat tttttaaatt tccaccccac ttacttaaat aatattttgc aatttcaatt
    12601 tcctctttat ttggtacaca catgtataca gaataatttt gcgttaaatc tacaatatac
    12661 ttatggggaa gaaaaggtgg ccatgcaagc atgacacctt taatcggttc ccattcccca
    12721 gctaaacgtc ttttcatttc taatacctca ctttcttact ttttccacaa atgaaatgga
    12781 atttctctaa ttttaagatt tttcaacaat gtttcaaatt catttttttg aaaggttttc
    12841 tgattacata aaacttccat ttctagtccc ttatactcca tgatatattc tgtttcataa
    12901 aacccattct gaagataaaa ttgcttcctt aaaattcttt gctgtaaatt aggagcactg
    12961 tcctctatag tttccatatc aagaacaatt tgacaattgg gatattgttt tttcataagt
    13021 gacagtgctt ttccaccata tcctttagag cgttgttctg gagaaattgc aagaaataat
    13081 atatatccta tatgattttc aatcaccaaa acataaaaac caataaattg ttgcttatca
    13141 tataaagcag atacttctat ttttttactt tgaactaaat taagcatttc ttgtatagac
    13201 atacgttctt catctggaaa tgcctcgtta ttaagttctt caaatttttc taaatcttta
    13261 aaatatgaag ttactttttg tattgttaag ctcatataga tacctccaaa ttgatttaat
    13321 aatgatattt tttctgtttt cttattataa agaaagccgt cataatagtt gccaatattt
    13381 cagcaccaac aatagaaaac catatcccat ttactcccca gaatataggg aatataagta
    13441 ctgatacaac ttgaaatact aaaatacgca taaaagcaat aagcgcagaa gttaaaccgt
    13501 catttaatgc agtaaagaaa ctagaaccaa aaacaccaaa accagaaaat aaaaaggaaa
    13561 aagagtaaat cataaatgct cttaatgtca tttccattaa attattatcg taacccacaa
    13621 aaataaaagc aatcggtttt gataaaaatt cgcctattat aaacataaat acagcaaaac
    13681 aaataattac aatcaaactt ctttttctta aattttttaa ttcgtcataa ttttttgctc
    13741 cataatgata actgattata ggggcagtac caacagaata cccaataaaa acagcttgaa
    13801 atagtaacgc tacataaaga agaacaccat aggatgcaac gccatcttcg ccagcatatt
    13861 ttagtaattg agcattatac agcatactca caacagatgt ggaaacatta gtcattagtt
    13921 ctgaagaacc atttgcaaca gtctttttca aaacatcaca atcaaattta ggtttcttaa
    13981 atttaagcaa actgttgttt tgtcggctaa aataaagtaa tggaatgata ccaccaacat
    14041 attgaccgat tgcagttgcc agtgctgcac ctaccaatcc ccatttaaaa acagtgataa
    14101 ataatgcgtc taaaacaata tttgtaattc cagccataat tgcaacatat aatccaagtt
    14161 ttggcttttc tgctgttgca aataaacact gaaattcgca ctgcaaaata taggcaggaa
    14221 tagcgataat taccacacat ccataaagaa tactatctgt caataattga ccatctgctc
    14281 ccatagcaga agcaatccat ggcatagtta ctatacctaa aacagctaga ataataccac
    14341 aaccagcaga agtaacaatg agtaacgaaa actgttcgtt tgcttcttct ttttttcctt
    14401 cacccattgt tttagcaatt aaagctccac cacctgttcc aaaaagaaag ccaacacacc
    14461 ctaagattag caaaaatggc ataataaaat tgacagcagt aaaagcagtt ttccctacaa
    14521 aatttgaaac aaaatatcca tcaacaaccc cataaataga acttattacc agcataataa
    14581 ttgtaggaaa tgtaaatttt aataagcgtt tataattaaa attatctgac aactgtatca
    14641 ttgttcatac ctcctaaacc aatactctga aaagttagca attgcataag aaagatgttt
    14701 tatattccat tcagatgtat taactataat atgataggaa gtttgatttc cccataagga
    14761 gctcgtaaaa aattctcttg atcttgctcg atttttatca atctctctta tctttctttc
    14821 taattctttt tttgaaatat gttcattgtt taactttttt tcaatacagc gttgtatttt
    14881 aaagttcata tttgcacaaa caaaaacgtt aaatggctgg tacttcttta ataatatatc
    14941 tgcatttcta ccaacaataa cacaatcctt acctgtactg gcaatctgat tgataacatt
    15001 tgattgttct attaacaaat ctgtcttcat ggattgcata gacaaaatat tagtaaaaga
    15061 agtacacatt gttaaaggaa cgtttctcca accatgattt tctaatatgt aggaaacata
    15121 gttttcgtca atttttttct ttctagctat agcagtgata atttctttat cgtagtagtc
    15181 aaaatttaaa atatcagcaa gttgttttcc aagttctcgt ccaccacttc caaactctcg
    15241 gctaattgta ataattttca taatatcttt tcctcacatt tcattgaata taaaagcttt
    15301 ctatgttatc ctaaagtatc tggtaaccct aaagtcaata ggagatttaa aaatgattaa
    15361 aaaattatat aagacaagtg aatttgcaga attgtgtggg gtaaaaaaac atacacttta
    15421 ccattatgat gaaattgaat tattaaaacc gagtattacc catgaaaatg gctatcggta
    15481 ttatacaatt gaccaatttg aaaaatttaa tattatttct gtgctaaaaa aagcaggtac
    15541 acctttagaa gaaataaaac aatatctcaa tgatttagat acgaatacct ttcttaatgt
    15601 acttcacaga aagctaatgg atcttcaaga agaagtgaag aagattgaaa aaatgtgttc
    15661 tatgttgaga aatgtcattt caacaatgga aatacatctc aatgtaaaca cagaaaaaat
    15721 cgaaattgta aattgtgagg aagaatatct gattgcaact aaaattcctg aagctgtact
    15781 aacagatgaa aaaacaatgt tacaaggtat tggaaatcac ttacaatatt gtttattaca
    15841 tgattataat tttcatgtag gagaaattgt tcttgaaaaa aatataaaac agggaatttt
    15901 tagagagagc tattattata gccttattaa aaataaagta gatgatgagc gcctttttat
    15961 taaaccaaag ggaaattatg cagttatgta tcaccagggg agttatgaca gtttatataa
    16021 aacttatcaa aatatgaaaa atcagttaga agaacaaggg tatcatattg ttggaaatat
    16081 ttatgaagaa gatttaattg attatttatc agaacataac gccgaaaact acattcaaaa
    16141 aatttctatg caggttattt gaaaatataa aaagcgtgta tatctcaaat cacatgagaa
    16201 atacacgcct tttttaatat ctcgtattgt ctataataat ttgcttaaaa tgtccttttt
    16261 tatcttctaa agttggtatc ttatttccaa atttttgtag aaattcagct tcattgctat
    16321 tatttgtttc ctcaatgcaa actgcatttc ctcatgaatt tcagatacag aaatagcttt
    16381 ttattttcgt taaccattta atcagttttt tactatcttt ttataaaatc ttaacatgta
    16441 ggctttatgc ctccatttct tttgtagttt tcttaaaagt agtgcaaatt tttttcttaa
    16501 atatatatta tataaattat tcatttatat agagtattat attatgatct gtaaatagtt
    16561 acaatattta aaagaatgaa aggagaacaa aaactatgga aattgattat aaagcaatcg
    16621 gacagcgaat taaaattgca agaattaaaa aaggtataac acaagaatcc gttgcaaaca
    16681 ttatcaacat gacaccatcc catatgagca acgtggaaac aggaaaaacg aaagtcagcc
    16741 tgccaacctt gattgcgatt gccaatgcac tttctgtatc agtcgatact ctcttatgtg
    16801 ataatgtact ttcttccaaa gtaatttttg aaaaggaagc caaagatatt ttctcagatt
    16861 gtgatgaata tgaaatccgt tctttagttg aactgctaaa atcagcaaaa actgtaatcc
    16921 gtaaagacag agaaatccgc aaacaatttg aaaaataaaa ccacagcttc aaggtataaa
    16981 ttgatatgtg ttgttagcta aggtcttttc tttttttata taatcatttt tatataatca
    17041 aataacctat ccaataattt tccaattact gtccttatga aatatcaatt tatactatga
    17101 tacctgtgtc gcttttgtct aattatcaag gaattttaca gctacctttt cattatcaac
    17161 aacaacagta aaaatagggt ttaccaattc agaaagtaaa tattcttgaa atatactatt
    17221 ttcctttcat aaaaatgata aaattttaat ttacatccca cgtaatgaag tgttcaataa
    17281 ataagttaaa ataatctatt tacctcctta atcatatttt ttatgaatac ctaataacac
    17341 agtatcaata gaatcgacta aaccttttat agcttcttct ttactcaaaa atgatttccc
    17401 aagttgcaaa gtcgaataac catgaagtac actcattatt aagtttaata cttcacctgt
    17461 attctttgta tttagattac aagaaagaat aagtttttct agtaaggatt tatattcatc
    17521 aaagatttct aatgtttcat tatttccatg ccaagtagcc cactgaattg tttcataaac
    17581 accaggatta gaaattataa aattaaagta tgctatactt atacacttta tagctgtatc
    17641 tccaaaattt ccaatagccg cctttatcat ttgactattc atctctctca ttcctttatg
    17701 agctacttca agtaataaat catctagact ttctatatga ttgtacaaag atggtgtacg
    17761 tattcctagc ttttctgcaa taacttttaa agaaactttg ttaagcccat ctttattaac
    17821 tatatctgat gtagcttgta taactatttc tctactaaca cgcatgattt tccctctttc
    17881 atttaaaatt aattacttta ttagtttagc taatctaatt agtttcgtca attattgtaa
    17941 tttataaaat tctttatact attataaaat cttgacagtt taattataat ttaatataat
    18001 actaattgaa ttagctttaa tactaattca attagtatta tattaaatta tatattacaa
    18061 cattatttta tagtttgatt aatttaacaa tcactaatat atcaaactga aaggagattt
    18121 ttatggaaaa aaaatatttc gaaattcatg gagttccttc aatcctttgg ggaaatcctt
    18181 caagtaaatt atatatttac atacatggac aatgtggcaa taaagaggag gctgaagctt
    18241 ttgctaatat tgcagttcca catgagtgtc aagttttaag tgttgatttg cctgaacatg
    18301 gagaacgtaa aagagaaaaa aattcattta acccatggca tgttgttcca gaattagtat
    18361 ctattatgga atatgcaaag tgccactgga atcaaatttc gttatatgca aatagcattg
    18421 gagcatggtt tagtatgtta agctttgaaa aagagaactt aagagagtgt atttttgtat
    18481 ctccaattct agatatgcaa cagctcattt caaatatgat gctttgggca aatgtatcag
    18541 aagaacagct taaacatgaa ctaattatcc caacttcatt tgggcatact ctttcatggg
    18601 aatatctaca atatgtaaaa caacatccta tcactcaatg gaatgtacca acaaaaatat
    18661 tatatggtaa acatgatgaa cttactgaaa tcagtgttgt agagaaattt gtagaaaagt
    18721 ttaattgcaa ccttactatt gtagaaaatg gcaaacattg gtttaacaca ccacaagaat
    18781 taaattcatt atatgaatgg ttaaatactt tagttaaata aaaaataatt atattattaa
    18841 tatgattaaa ttatttataa atgttattta attaatttta ttttagcatt attaaaataa
    18901 ctacataaag a
//
LOCUS       DAEQAF010000073        18695 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.076, whole genome shotgun sequence.
ACCESSION   DAEQAF010000073 DAEQAF010000000
VERSION     DAEQAF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18695
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.076"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            212..1429
                     /locus_tag="KRN00_002666"
     CDS             212..1429
                     /locus_tag="KRN00_002666"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBH1828524.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            1524..1904
                     /locus_tag="KRN00_002667"
     CDS             1524..1904
                     /locus_tag="KRN00_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1828525.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            2188..2670
                     /locus_tag="KRN00_002668"
     CDS             2188..2670
                     /locus_tag="KRN00_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1828526.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSNVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            2691..3506
                     /locus_tag="KRN00_002669"
     CDS             2691..3506
                     /locus_tag="KRN00_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1828527.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            3557..5107
                     /locus_tag="KRN00_002670"
     CDS             3557..5107
                     /locus_tag="KRN00_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1828528.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIVGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            5204..6556
                     /locus_tag="KRN00_002671"
     CDS             5204..6556
                     /locus_tag="KRN00_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBH1828529.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKERQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGSHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            6687..7445
                     /locus_tag="KRN00_002672"
     CDS             6687..7445
                     /locus_tag="KRN00_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1828530.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLGIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDNN
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            7492..8211
                     /locus_tag="KRN00_002673"
     CDS             7492..8211
                     /locus_tag="KRN00_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBH1828531.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDATKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(8335..9735)
                     /locus_tag="KRN00_002674"
     CDS             complement(8335..9735)
                     /locus_tag="KRN00_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBH1828532.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(9739..10647)
                     /locus_tag="KRN00_002675"
     CDS             complement(9739..10647)
                     /locus_tag="KRN00_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1828533.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            10908..11555
                     /locus_tag="KRN00_002676"
     CDS             10908..11555
                     /locus_tag="KRN00_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1828534.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            11879..14518
                     /locus_tag="KRN00_002677"
     CDS             11879..14518
                     /locus_tag="KRN00_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH1828535.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(14576..15679)
                     /locus_tag="KRN00_002678"
     CDS             complement(14576..15679)
                     /locus_tag="KRN00_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBH1828536.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVESFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            16040..16861
                     /locus_tag="KRN00_002679"
     CDS             16040..16861
                     /locus_tag="KRN00_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBH1828537.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    16940..17151
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            17238..18554
                     /gene="argH"
                     /locus_tag="KRN00_002680"
     CDS             17238..18554
                     /gene="argH"
                     /locus_tag="KRN00_002680"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBH1828538.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
BASE COUNT         7149 a         2155 c         3309 g         6082 t
ORIGIN      
        1 agaatgtaaa aaatattttt aaattatcat ttaatgtaat ttaaatgaat tgaagatata
       61 tgtttattgt atgcaattgt tgtattttta ggttttttgt gattaattaa aaaattataa
      121 aaatcgttta catgttgatt tttaaaaaaa aaagatatag aattatatag aaagtaataa
      181 acaaaaattg gatttacggg agtggaatga aatgatgaat gttaccttaa cagatgtgaa
      241 agaggctaga gagaccatta agaacatagt aaaaagaact gacttacttg aaagtgttaa
      301 acttagcgaa aaaacaggag caaatgtgtt ctataaatgt gagaatcttc aaaaaacagg
      361 ttcttttaaa ttaagaggag cttgtaacaa aatagcgagt ttaacagatg aagaaaaggc
      421 aaatggagtt atagcttcaa gtgcagggaa tcatgctcaa ggagttgcat tgggagcaaa
      481 aatgactggt ataaaatcta caatagtaat gccagcaact gcgcctttag caaaagttag
      541 tgcaactaaa ggctatggag cagaagtagt tttaaatggt gcggtttatg atgatgcata
      601 tgcaaaagct gttgaaatac aaaaagaaac aggagcaact ttcttacatc cattcaatga
      661 taagtatgtt atagcaggac aaggaactat atctcttgaa attttcgaac aattagacaa
      721 taaagttgat actatactat gcccagttgg tggaggagga atcatctctg gtgttgctgt
      781 tgcagcaaaa gcattaaatc ctaatgtaaa aatagtcggt gttcaaactg caaatatacc
      841 ttcaatgaaa gagtcaataa aaaatggaaa agtaacaaca gcatttaatg atactacaat
      901 agctgatggt atagctgtta aaactccagg agatttaact tttgaaataa taaatgaatt
      961 ggttgatgaa atagtagtgg ttgaagagac agaaattgca gaatcaatat tatttatgat
     1021 ggaaagtcaa aaaatagttt cagaaggtgc tggtgctgta tgtacagctg ctatattaag
     1081 tggtaagtat gtaccagcaa aagatgaaaa tgtagtttgt ataatatctg gtggtaatat
     1141 agacataaat acgttatata gaataatagg tgttgcttta gctaaagaag gaagaagata
     1201 ttcatttagt acaattatgg aagataagcc aggaaacttt gctgagttaa ctagaataat
     1261 aagtgagaat ggtggaaaca ttttaagtgc taatcaaggt aaattatcag caggggaagc
     1321 tctaggaaaa caaagtgcgg aatttatatt agagacaata gattatgacc atatagctag
     1381 aataaagaaa gctatagaag aaaaaggttt taaaattata gaattataat aaaaagtgta
     1441 tataatatac aagaaaaata gtataatagt gtatgaagat acattttatg tgtattagat
     1501 taacgaatta ggaggatttt aaaatgaaac atgaagtaat acatactaat gatgcaccag
     1561 cagctttagg accatattct caagctataa aagctggaaa cttattattt gtatctggac
     1621 aagttcctct tgtaccagag actatggaag tagttgaagg agatgtacaa gctcaaactg
     1681 ctcaatcttt aaaaaatctt aaagctatat tagctgaaag tggagctgat ttttcaaatg
     1741 tagttaagac tacagtattt ataaaagata tgaatgaatt tggggctata aatgaagttt
     1801 atgctgaata ttttggagaa aataaaccag caagagcttg tgtagaagtt gctagattac
     1861 caaaagacgt taaagttgaa atagaagtaa tagctgtatt ataaaaatac aatattttta
     1921 atttgaaaag gctgaaaaac tatattctag tgattcagcc tttttataaa aaaataaatc
     1981 acaataaaga acatgataaa tattgtcgaa ttaaaaaata aaattaaaat aaatattgca
     2041 atatttttga gaaggtttta taatgagtat ataatttgaa acgtgtaact attaaattag
     2101 gcatgagttc ttggatattt ttatcctgag gattcatgcc ttttttgtat tgaaattcaa
     2161 aaatctattt aataaggagg aagtactgtg ttaaattttt tcaagaaaaa taaaagctat
     2221 aagttacatg cagtagtgag tggtaacagc attaatattg agaaagtaaa cgattctgtg
     2281 ttttcaaaaa agttaatggg agatggagtt gcaattattc ctaatagtaa tgttgttgta
     2341 gccccttgta atggtaaagt aactgtgctt acagaatcaa agcatgcctt tggtatggtc
     2401 tcagatgagg gtgttgaaat attagtacac ataggaattg atacagttag tttacagggt
     2461 gaggggttta aaaatgaagt gtctcaagga gatactgtta aaaaaggtag tccaataata
     2521 agttttgaaa gagaaaaaat aaattctcag ggaattgatt gtacaacaat aataattgta
     2581 ttaaatcata gcgaattttc agaaataaat tgcatggtag aaaatgaagt tgttgcaggg
     2641 caagatactg ttattgaaat tatgaaataa taggaaggga ttaattcaat atgagagtag
     2701 taaaaatctt taataataat gcattatcta cagtaactaa tgataggaaa gaagctattt
     2761 tactaggtct tggtataggt tttaataaac gtccaggaga taaagttaat gaagataaaa
     2821 tagaaaagat ttattatgtt caagaccaca tgcaaacaaa atttttagaa ttattaaaaa
     2881 atgttagtcc agaagtgatg gatgcttcac aacaaattat aagtcttata ccaggaaatg
     2941 agggaaaatt taataataaa gggatattat ctttagtgga acatattagt tttgcaatag
     3001 atagaatgaa aaataatgtt tttttaccta atttaatgct tttggatata aagatgatgt
     3061 attcaaaaga gtttgaatta ggagtaaaag ctttagaaat tatatataga gtatgtcata
     3121 tccatttgcc tgaagatgaa gcaggttaca tagctttaca ttttgtcaat ttacaatcaa
     3181 atgataattt ggcatatgat actttaaaat ttgtaaaagg tagtattgat ttgattaaag
     3241 aatgttatgg attagaatta gacgaatcga gtttaagtac attacgtttt agaactcatc
     3301 ttaaatttct tgctcaaaga atttttaaga atgaaatttg tcaggatgat aaaatgattg
     3361 aaatgtatga ttatttaatt aacaatcatc ctaaaaataa agaatattta gaaaagttaa
     3421 atgtatatat tgaaaaggag tttaggtata aattagataa acctgaaaaa atttatctac
     3481 tactacacct aacaaaaatc ttataagaat gagatgaatt agtaatagaa atatataatt
     3541 ttaggggggg ataagattga aagaaaaact acttggagga ctggaaacat ttgcaaaggc
     3601 aatggttcag ccattaatgt atttatcgag tgcaggaata ttaatggtgg taggtgtact
     3661 acttacaaat gatatgttat taggagtact tccatttttt aaatgggagc caattcaaat
     3721 atttggaagc ctaatttata actgtataat ggctattatt aataatcttg ctgttatatt
     3781 tgctataggt attcctgctg cactagcaaa aaaagagaag cacaaagcag cgttaatagg
     3841 atttatgagt tatataatat accttacagc ttccaacact atgttaacat cactaggtca
     3901 actagcaaaa gaaagcaaga tgcttggact gatagggact ggacaagcta ctattttagg
     3961 tattcaagtt gtagacacaa gtgtatttgg tggaattatt ttagggtgta tagttggata
     4021 tgtatttaat cgtacaagca acaaaacatt taaaggagct ttacagatat actcgggagc
     4081 aaattttagt tttatatgca tgttctttgt atccatttta attggagttg tgagtaactt
     4141 tatatggcca ttagctcaac aaggaatagc ttctcttgca aatgtcatca aagatacagg
     4201 tacatttggt ttattcttat atggtttttt agagagaata ttagtaccaa ctggacttca
     4261 tcatttaatc tatacaccat ttcagttttc tgatttagga ggagtgctta aagttggtgc
     4321 agatacagtt tcaggagcct atgctatagt tatgacagaa atgaatttac cagttgagcg
     4381 tttctcagat agtatatact acatggcaac tggatttaca aagatgtttg gttatatagg
     4441 tataggagct gcctttattt atactgcata taagcaaaat aagaagaagg ttaaggcaac
     4501 gattattcca ctaataatta cggcagtatt agcctctgta acagaaccat tagactttat
     4561 gtttgtattc tgtgcaccac ttttattctt tgtacatgca gttatagctg gtctttttat
     4621 agctttatta aaaatatttg atgttactgc attatgtgga gggaacttat tagtatcaat
     4681 tataatgaat actacagtag gtgtagaaaa aacacactgg ccagtaatga tgatattagg
     4741 acttgcacaa attattgtat attttgtagt atttagtttt ttaattaaga aatttaatta
     4801 taaaactcca ggtcgtgaag atgagagtac agctacaggc gaagaacaat caaaacaact
     4861 taatttagat gcaggtatag aaaatataat tgatgggtta ggcggaaaag aaaatattaa
     4921 tacagtagaa aattgcatca ctagattacg tgttaatgta aaagatgaaa gtaagattaa
     4981 tgaagatata attaatttaa cgccaaatag cgggattgta aggaaaggaa aagatataca
     5041 aataattttt ggacttcatg tgcatgaggt aagacgtgca gtagaagatt ttttagaagc
     5101 ttattaaaga tatatattta tatagcaagg gtaaataaca gctttaagtg ctgtttacta
     5161 tttattaaag atacatataa tttatagagg aggaataatt attatgatta ttactattgt
     5221 tggtggagga agcacattta ctccaggtat tgttaagtca attgcgttaa gagaaaaaga
     5281 gttagagctt gaggaaattc gcttatttga cattgataaa gaacgccaag ataaagtagc
     5341 tgtagttgtc aactggatac taaaagaaga tgttaaaaca gatgttaaac taactgtaac
     5401 taattgtgaa aaagaagcgt atacagatgc tacatttata tttgcacaaa tgcgtgttgg
     5461 taaatatgaa atgcgtgagc aggatgaaaa aattccattg aaatatggtt gtgtaggtca
     5521 agaaacttgt ggttgtggag ggatggcata cggactgcgt acaatacaac caatgataaa
     5581 ggttattgat gatgtagaga aatatgctaa aaaagattat tggatattaa attactctaa
     5641 tcctgctgca atcgtttctg aagcttgtcg taagttaaga ccaaatgcaa ggattataaa
     5701 tatctgtgat atgccaatag ctattataga tatgatagcg gggtcattaa atatcaatga
     5761 cgttcataat atacgctatg attattttgg tctaaatcat tttggctggt ttacttcaat
     5821 agattataaa catagagact taatggaaga gattaaggaa tacataaaag aaaataaaat
     5881 attattacca aaatcttata tagaaaactt aaataaaagt cgtagtacag gaaatcgcca
     5941 tgctgtaagt agctggatac atgtttggga atctgtttat acaatgttag aaagcttccc
     6001 aaaatatcta ccaaacactt atttaacata ctatctttta agtaaagaaa cagtggaaca
     6061 ttcaaacata aatcgtactc gtgcaaatga ggttatggaa agccgtgaaa aagacttatt
     6121 tgaaggtgtg agacattact tagaaactgg agaaatttct gaaaaagcat tttatgcagg
     6181 ttcacatgga gattggatta gtgatttggc agtttcaatt aaaaatgata cacgtagtcg
     6241 ttttttagtt ataactgaaa atcgtggagc tataccaaac atgccatatg atgcaatggt
     6301 agaaattcca gcatatattg gtaaagatgg tccagaagtt attgctcgag gtccaatacc
     6361 tctattccaa caaggattaa tgatgcaaca acttaacagt gaaaaattga tagtagaagc
     6421 ttatatagaa aatagttatg aaaaagcttt acaagcattc acattaaata aaactattcc
     6481 aagtatgaat gttgctaaag aaattttgga tgaaatgata gaagttaata aggaatactg
     6541 gccagaatta agatagtagg ataaaagaaa gggtttttat ttaataatta gatatgtttt
     6601 cagagtcttt tatcaaaatg tattcacaaa catatggcaa tatattaaaa taaagagtga
     6661 tatttttaga agaatggggt gatgcaatga acattataaa taaaattttt tggcaagaag
     6721 ataggattgg catgattaca aataatttag aggcagatac acatagccac tgtatgttac
     6781 aactgttctt agggatagaa gacagcattg aaataacagt taatgaaaaa ttagttaaat
     6841 gtaattgtat catagtagat aaaaatatct ctcattcatt ttcagcaaga aaaaaagttt
     6901 attactctgc tattattgaa cctacatcta tatatgcaga acagcttacc tcaaaaatga
     6961 atgattttgg ctactggata tgtgacaata atggattaga gaaattacgt caacaaggaa
     7021 cttttttgat agataactct agtaaagaac aatatttaag atttatggaa atgcttaata
     7081 actatttgaa tatacctata actctaaaac attatgatga cagaattact gaattgctca
     7141 atttattacg tacttgtaat tgtgataatc atactatttc aagttttgca gataaagtgt
     7201 ctctatcagc aagtagatta tcacatctgt ttaaagaaca aatagggata cctttaaaaa
     7261 gctatatctt atttcatcaa atggagtgtg cttttagaga attactttct ggaaaaaatg
     7321 ttaccgaagc ttctatgact gctggattcg atactccatc acactttgca gggacagtta
     7381 agcgaatgat gggaatgcct gtttctttat ctttgaaaga tagcgagttt ttgaaagtat
     7441 attaaatatt ctcgttatat aatgaagttg tactaagaaa ggggctttgt tatgaataaa
     7501 gaatatttag aagaaacaaa aatgttaaat tataatgaac cacaacttaa gcttttggta
     7561 tcatcaaaga attggttgga attagatgat tttcataaaa taaaatctat ttatgagttt
     7621 gtacagaatg atattttatt tggatataat gcttctgata tgttaagcgc aacacaggta
     7681 ttaaatgatg gtatgggaca atgcaataca aaagctactc ttttaatggc attattacgt
     7741 gcagtgaata tcccttgtag gcttcatgct tttgatgcaa caaaagattt tcaacgagga
     7801 gctacatcca aattgatttc actattagca ccaaaatata ttcttcatac ttgggtagag
     7861 gtattttatc aagataggtg gattgctctg gagggtgtca taactgataa aaaatattta
     7921 gaagcaattc agaagaaatt ttttaatcat ggtggaacgt ttaaaaagta tgcaatagct
     7981 acaaatgatt tgaaaaatac atctattgat tgggatggta aagatacttt tatccaaaaa
     8041 gaagctatcg tgtatgatta tggtattttt ccatcaccag acgtattttt ttctactcat
     8101 tcacaacata tgtcaaaatt aaaaaatttc atatatgtac atcttatcag aaaaataatg
     8161 acaaaaaatg tatgtaaggc tagaaacaat tatattgata aaaatgaatg agtgtttaag
     8221 aggtaactat ataggaaata tatagaataa ttaaaactgt actggttaaa atgaataaaa
     8281 aggagttatc acagagcaaa cttaaattgt tcataggata actccttttc tgtattaact
     8341 tctaataatt tgatgtcttt ttataaaaca tatagataca attaaaccag taaatgcaag
     8401 agtagctgct attgaaaatg caacatctat tccatgaatg ttagacagca tgtttgaact
     8461 catatgagct ttcttagtag cacttgtcat tatagtaata agtatagcag aacctatagc
     8521 tccagatatc tgacggagtg tgttattaat tgctgtggca tgagatataa gttctctatc
     8581 taatgtttta attccccatg tagttaatgg cattaaaacc attgaaatac caatcatacg
     8641 aatacaatac atcaatgaca catgaattaa agatgtatct ctgcctaaaa aagcgaagga
     8701 taaagttcct aaaaacaaac atcctgttcc taatattgat agagcatgag gtccatattt
     8761 atctaaatga cgtcctgcaa ttggattgag tacaaccatc aatatagcac caggtaacat
     8821 taatgaacct gaagataatg cagaaaatcc tcttacagat tgaacgtaca gaggaatcat
     8881 taatgtagca gacatcattg aggcatatac aatcataatt aatattgtag aaataagaaa
     8941 tggtttattt ttaaaaaccc tcaattctaa aaaaggttct ttagatttta attgacgcaa
     9001 tgtaaataaa attaatgaca taattcctat taatattggt aaatatgtgg caatattagt
     9061 ccacccataa ttaccttgat tagtaaatcc aattaataaa ccaccaaaac ctagagatga
     9121 tagtactatt gaaggtatat ctaattttag tttttgagtt tccccaacat ttcttaatag
     9181 aataaatgat agtataacat ctaatatagc aataggggaa agaaacagaa ataaactatg
     9241 ccaaccaaat gaatctacta accatcctga taaagttgga cctattgctg gagcaaatcc
     9301 tactgtaata ccaactaaac tcatagctgc accacgtttt tcctcagggc ataaatagag
     9361 tataataact tgtaaaagtg gcattagaga accagaaccc attgcctgca acacacgagc
     9421 aatcaacata gttgaaaaat tattagaaaa aagtgcaata atacatccta tagaaaagat
     9481 agacattgat gtaataaata actttctagt actaaatcga tttattaaat aagctgttgt
     9541 gggtacaata atacctgcaa taagtagata aattgttgtt aaccactgac caacatcagc
     9601 agtaatttta aaatctgaca ttatattagg taatgctgtt gacaatagtg tttgactgag
     9661 agaacttata aaagcaccag tcattacaat tgctattatt aaatttcctt ttttattgtt
     9721 actttgggtt tccataattt ataacgtctc cttttttaat tgatttttaa tgctgttcaa
     9781 taaaagtact tttggtctta aagtgtcttc tttttctaaa tatgcaatca ttgcatccat
     9841 aattaaagaa tcatattgtt gattttttcc ctcgacgtat aattttttta ttgcttctag
     9901 taatttagga ttttcaagga gagaagtatc agttttgatt agttcttcta tatcttgtat
     9961 cgttttaaaa aatagcgatt tattatgaag ggaaaagtaa acttcatctt cttgtttatg
    10021 taaaaacatt gatttttcaa ttaaaggatt tagattatcc atattttcta caactaaatc
    10081 tagaatttgt atagtaaatt tggcaataaa gtatacattt atttctcttt tttgtacatg
    10141 aataatgtat ataaactgat gaattagagc atccaataag aaaactaaat caaatataat
    10201 tttttctatt ttatcaccat agttatcaaa taagcttaat ttgtattcat tcaataagtt
    10261 agctcgtgat tttgtttgca atttacttgt agccttacgt tgctcttcag aaaagttttc
    10321 tcttatatag gtatttatgg tagttctaga aaaaatattt ttccatacag caattatctt
    10381 tctgtttaac ttttctgatg atggaatgtc attattttcg tttatggaat gtataatttc
    10441 taaaaacttt tcatcataat aattgattat ttcgcagata aaactttcct tagtttcaaa
    10501 atgcttgtaa aaagtagctt tagacatttt acactctttt acaacatccg atattgaagt
    10561 attttgaaaa cccttttggt caaaaatttt ttgtgcaata gttataatga gcctttgttt
    10621 ttctgtcact ttattatctc ctttcacgca aaaacgttta gtactatata gtacctacaa
    10681 gttttaataa atatattata catcatttgg aaaaaaaatc aatatataga ctgtaatatg
    10741 aaatttttga aaaatttgtt gttattttta gtcgtataaa aaagaaactt aagagtttct
    10801 taagaattgt ttaaagaagt tgcaataaat tagtggtatg attatagtat gaaagagaat
    10861 gtcttgaaat ttttctgtat caaattccaa ttatggaggt gtagtatatg aaaaagaaaa
    10921 tttgtgtagc aataattttt gctctattta tagtttttgt agaaatgttt attgatagct
    10981 ctagcgaagg aagtaaaatt atgacagctg aattaagtaa atacaggaaa ggcgtaaatg
    11041 tattatcaat aaacaatatt atagtagcga ataaaaaata tagtttgccc aaagattatt
    11101 ctcctcagga aagcagtgaa gcgagagatg ctttttataa aatgaataaa gatgctcaaa
    11161 agtcaggatt aaatttaaaa gcttttagta catatagaag ttatgaatat caagatagat
    11221 tatttaagtc atatgtaaaa gaacatggag aaaaagaagc aaatagattt tcagctaaac
    11281 ctggagagag tgagcatcaa actggacttg cttttgatat tggaggagat gaccagtctt
    11341 gttgggcaaa taaaaagttc aacaatacaa aagaagctaa gtggttgtat gaaaatgcat
    11401 ataaatatgg ttttatactt agatatccag aaggtaaaga gaatataaca ggatatatgt
    11461 atgaatcttg gcactataga tatgttggaa ctgaacatag caaaaacttt gcaatgaata
    11521 atttgacttt agaagaatat ttacatataa attaagagat ggtttgttaa aattaggtta
    11581 aaataaaaaa taacctagac tattagctgt gtaaagtgat ataatgtaaa tacaatttag
    11641 ataactactc gaaggggagt agcttacacg aaagtggtaa ttaatcgtca agacagtaga
    11701 aatactcggt taattagcaa gggattcctt gatagcaaga ccttcaaaat aagcattagg
    11761 tatgtttgtt ttggggtctt tttttattca aggaattttt atttaaaaaa atttaaattt
    11821 caagtataca taagagcccc caaacataaa ataaatttat tgaagaggag ggcaacaaat
    11881 gtcttacaaa agtacttatc aagaagtaat taaaaattta gactcaagtt tatctggttt
    11941 gagtaaagaa agagcagaag agttgttaga aaaaaatgga gctaatgaat taaaagaagc
    12001 agataaggtt cctacttata agcttttcct agaaagtttt aaagacccat tagtaataat
    12061 tctattgata gctgctttag tacaaatatt tttaggtgaa acagtggagt ctataataat
    12121 ttttgcagtt attattataa actctgttct gggtgttgta caaacaaaaa aagcagaaag
    12181 ttcattagaa agtttgaaaa atttatctgc accaaacgca aaggtaataa gagacaataa
    12241 aaaaatgaca attccagcaa aaaatctagt agttggagat attgtattct tagaagctgg
    12301 cgattacata ccagcagatg gaaggcttat agaagcacaa tctctcaagg ttgtagaagg
    12361 gatgttaact ggagaatcag aaccagtttt aaagcataca gaaaaaataa gtgaagatgt
    12421 aagtttaggt gaccagaaaa atatggtatt tagtggtgct gtagttgttt atggtagagg
    12481 ttcttttgta gtgactggaa caggtatgga tactgagatg ggtaaaatag ctgggctttt
    12541 agaaagtgct gaaaataaac ttacaccatt gcaacaaaaa atagaggatt ttagtaaaaa
    12601 acttggtgta ggtattgtaa tacttgctct tttaatattt ataattcaag tagcaagaaa
    12661 ttactttatg gctggaaatg gagaaatgac acaaattatt ttagattcat tcatgttctc
    12721 tgtagcagta gcagtagcag ctataccaga agctctatca tcaatagtca ctatagtatt
    12781 ggctgttgga acaaatagta tggcaaaaaa acaagccata ataagaaaat taccagcagt
    12841 agaaacttta ggttcaacaa gtgtaatatg tactgataaa acaggtactc ttacacaaaa
    12901 taaaatgaca gtagttgatt attatatgta tggaactaat aatgatgagt tagataaaga
    12961 aaaagtaaac tattcttatc atgctaaatt attgactatg gtttctacat tgtgtaatga
    13021 ctctcatata actagtgatg gtaaagaagt tggtgaccca acagaagtgg ctttaataaa
    13081 ttattcaagt aaaaatgatt tagattatga taaattaaga agtaagtata tcagaataaa
    13141 tgaaatacca tttgactcag acagaaagct tatgtctact gtaaatagta tatatggaga
    13201 ttatataatg tttacaaaag gtgctccaga tattgtgttt agtaggtgta aatatgcttt
    13261 gaaaaatggt tcaaaagtag atataacaga tgagataata gaagaatata aacataaaaa
    13321 tgaagagttt tcaaatagag cacttagagt attagctttt gcaataaaag atgtcccaga
    13381 agaagatttt ataccttcaa ttgatgacga acatgacatg acattggttg gaataatggc
    13441 aatgatagac ccaccaagag aagaagtaat ggatgcagta aaagaggcaa agagtgctgg
    13501 tataaaaact gttatgataa ctggtgacca taaaacaaca gcagcagcaa ttgcaaaaga
    13561 gattggtata atggaagaag gagacttggc tcttactgga aaagagcttg atgctttgag
    13621 tgaagaacaa ctatatgaaa aactagaaaa tataagtgta tatgccagag tctcgccaga
    13681 aaataaaatt cgtatagtaa aagcatggca acataagaat aatataacag caatgactgg
    13741 tgatggtgtt aatgatgcac ctgcattaaa acaagcagat ataggaatcg gtatgggaag
    13801 tggtactgat gtagcaaaag atgcttctgc tatggtattg gttgatgata actttgcaag
    13861 tatagtaaat gctgttgaag ttggtagaac agtatacagt aatataataa aatcaattac
    13921 ttatctattt gcaggaaact taggagctat agtatccata gtatttgcag tgtttgcagg
    13981 ttggtcaaat ccatttacag ctttacaact tttgtttata aacttagtaa atgactcttt
    14041 accagcaatt gcattagggt ttgaaaagtc agaaaaaaat ataatgaata aacctcctag
    14101 acacccggat gaaagtatac tagcaggagg aacattgaag gcagttgcta taagaggttg
    14161 tataataggt gtagttacaa taattgcaca atatatagga ttacaagtat ctccagaact
    14221 tggagtagca atggcatttt caacattgat attagctaga ataatgcaaa cattacctgc
    14281 acgttctaat aatcaaacag taataaaatt aggttttttc agcaataaat acgttatagg
    14341 agcagtttta gtctgtcttg ggctttactc tttaacacta ataccagtgc taagaggaat
    14401 attctctata ccaacaacgt ttggattgta ccagttgggg atttgcctag ggttagcatt
    14461 aatttcatca atattaatgg aacttaacaa attaataaat agaagtgaag taaaataatc
    14521 aaaaaattaa agggcatatt gattttaaca atatgccttt tataaatagt ctaatttatt
    14581 ctatattatc gattatttgg aatgctttta taacttcagg taattctttt tcttcaggca
    14641 ttctaaatct tatgaaattt ttatcaagtc cagtaaaatc acttccagat ataactctta
    14701 tttttaattt agcaaactct tgttgtaaat ctatgtcctt gtttttatgt tcaactgtca
    14761 taattgatac agtatcacta gtttcagcta tattaaggtt tttccatgga attaataatt
    14821 gattttttat atcttttgtt ttttctttta attcttctat aaattgaaca tcatctaata
    14881 aatttgctgc aatactacga gatatttcag acacttcgta aggagtagaa atctttttaa
    14941 tagggctaac aagttgttct ggaagaactg catatcctgc tcttagtcct gctaaaccga
    15001 atccttttga aaatgttttt aaagcaatta cattatcata attatttaga agcttgacag
    15061 ctgaattttc ttttggcatg tattcaccat aagcttcatc taccataact gctatatcat
    15121 atttagctgc ttcctttact atattttcaa ttgatgataa aggtataatt tgtcctgtag
    15181 gattgtttgg attgtctatg taaattactt tatattctgg atttattttt tcaataaatt
    15241 ctttttcatt aaacttgaaa ttatcctctt tctttaaaag aacataatca taagttgcac
    15301 catgcatttt tatatctgtc tcatattctg agaactgagg tgaatatcct aaaactttat
    15361 ctcccttttc aataaatagt ctatttaaaa ggtaaataac atgtatagaa ccatctgcca
    15421 aacaaattct gtcagtatct aatgctataa aatctttcca ataatcaact atattatctt
    15481 ttaaagcaat tgaatgagga tatcctctta tcatatcaaa ttttaaagca ttaaaagatt
    15541 ctacagcttt gtttgagtaa gacacggtat ttataccttc accacagtct atctcgaata
    15601 catcttctga atgtccagat tctattgcat aacttttttt caactgcatt tcaatagctt
    15661 tgttaatttt tagtttcata ctttatcact ccttatttag tcaataataa atgttataaa
    15721 agttgctaga tttaaaatat tatgaaaata tataatagta aaaaatgaat ataaatatta
    15781 taatagctca ctttatttaa tatgattata tatcatatat tgtaaaattt ctagcattat
    15841 aagactataa attgaaaata ttcagaaaaa tactacaaga aacgatttat tttgctctta
    15901 aaataagtta aatgaatgtt attaattttg taaattgaaa tagtttaagt ataaagttat
    15961 gatataatct aataagggta attctttaga ttatattaag gaaatatagg tatacaataa
    16021 aaagttatgg agttggatta tgggatataa attaattgta acagatatgg atggaacttt
    16081 attaggcaat aatcataaag ttacagatga aaataaaact gcactacaaa aagttataaa
    16141 aagcggtatt aatgtaactt tagcaacagg aagagccttc gattcagcta aatgcaatgt
    16201 agattttctt aaagaggaca tgccaataat agcttgtaat ggttcattaa taagagagca
    16261 aaatggaaat ataatatatt caaataagat tgatacaaga acatgtttaa acattttaga
    16321 tgtattagat aaatacgata tttactacca atgtaatagt atagattcta tgctttcgaa
    16381 aaaaatagaa ggacgtgaag atagattaag tgtattttta ggctctgaaa cagaagtaat
    16441 tgtaaaagat gatttgagag aagaaatctt taaaaaagat atactaaaat ttgtaatcat
    16501 agaagaaaaa aatccatcta ttttagatga aataagaaaa gaattgagaa aagttcaagg
    16561 aataaagata acttcttcat ggccaaacaa tattgaagtc atgaatgaag gtgttgataa
    16621 aggtaatgca gttaaaattt tagctgaaaa aatgaatata gacagagaag atataattgc
    16681 atttggagac aattacaatg acatagaaat gataaagttt gctggtcttg gggtagctat
    16741 gggaaatgca gaagaattga ttaaacaaga agctgattat gttacagata caaatcaaga
    16801 cagtggagtt gcaaaggcaa tttataaatt cctagagtta aaagaatcac ttagctctta
    16861 aaacagtata taataggaaa aaataggttg actattttgt agatagtaat tataatacaa
    16921 atagataaaa cataaaaatt tagattcagt gaaaaagaga gtagatatag agaaaatctc
    16981 agcgaattgg gggatggtgt gagcctaatg ataacacttt atattgaaaa gaactttgga
    17041 gaatactact tgaaattcag tatggtagta ggtaatctcg ccttaagaga atagagtggg
    17101 taaacattgt ttaccaacta gagtggtaac acggaatatt tcgtctcttg gtctttttga
    17161 ccaagagatt ttttagtttc attgagttac aagacttata attaaaatac aaaaaattaa
    17221 aatatgaggt gaaagttatg aaattatggg gcggacgctt tagaaaagcg gaaaatcaac
    17281 ttatggaaga atttaataaa tcttttggct atgattgtgt actgtacaaa aaagatatcg
    17341 aaggaagtgt agcacatgtt catatgcaag taaaatgtgg acttttaaca gaagaagaag
    17401 gaaagtctat aacagaaggt ttaaaaggga tacttgaaga tgtagaaaat ggaaagttag
    17461 tattggatgg agagtatgaa gatatacata gttttactga gataaattta attcaaagaa
    17521 ttggagatgt tggcaagaag cttcatacag cacgtagtag aaatgaccaa gttgcagttg
    17581 atatgagatt gtatgctaaa gaaaaagcaa atgatttggt ggatttaata tctgaattta
    17641 aagctactat aaaagatgtt gctgacaaaa acccagtgat gatgccaggc tatactcatc
    17701 ttcaaagggc acaagtagtg acatttaagc atcacttaat ggcatattat agtatgtttg
    17761 atagagatga gaaaagaata aaaaatgcta tagaaatatt agatgaatca cctttaggct
    17821 gtggagcttt agcaggaact acgcatgata tagatagaag tataacttgt gaacaattag
    17881 gatttaaaaa agtagtagat aattttatgg atggagtaag tgatagagat tatttactag
    17941 agctaatgag tgatttttca attataatga tgcacttaag tagattaagt gaagagttga
    18001 tactttggag ttctcaagaa tttggatttg ttgagataga tgatttatat acaactggaa
    18061 gtagtataat gcctcagaag aaaaatccag atggtgcaga gcttataaga ggtaagactg
    18121 gcagagtata tggaaactta tttggtcttt ttacagtaat gaaaggaata ccattagcat
    18181 ataataaaga catgcaagaa gataaagaag gttttttcga tagtgtacat actcttgaaa
    18241 tgtgtataca aataatggat agaatgatag ccacactaaa ggtaaatgag gataaaatga
    18301 aacaagcagt aaaaaatggt tttttaaatg caacagaagt tgcggattat ttggttaaaa
    18361 ataatgttgc ttttagagat gcacatggta tagtaggaag tatcgttata tattgtgaag
    18421 ataataaaaa agcaatagaa gatttaacat tagaagaatt acataagttt tcagatgctt
    18481 ttaaggaaga tatttatgat tttatcgact atgagagtat attaaataag ggaataaaaa
    18541 agaatttaaa ataatgtatt tatttttaaa agctgtaaat ttgaatgtta tcatttaaat
    18601 ttacagcttt ttattgtgta agattttatt atataaaagt aagaaactta aaagtagtag
    18661 tatttaaaat aaatacaaat aaaaaattgt tatta
//
LOCUS       DAEQAF010000074        18460 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.077, whole genome shotgun sequence.
ACCESSION   DAEQAF010000074 DAEQAF010000000
VERSION     DAEQAF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18460
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.077"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     regulatory      34..136
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            230..1606
                     /locus_tag="KRN00_002681"
     CDS             230..1606
                     /locus_tag="KRN00_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBH1828539.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     gene            complement(1720..2865)
                     /locus_tag="KRN00_002682"
     CDS             complement(1720..2865)
                     /locus_tag="KRN00_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1828540.1"
                     /translation="MNTFEQLKISSILIDGLKKQDITSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            3118..3825
                     /locus_tag="KRN00_002683"
     CDS             3118..3825
                     /locus_tag="KRN00_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828541.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            3872..5467
                     /locus_tag="KRN00_002684"
     CDS             3872..5467
                     /locus_tag="KRN00_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828542.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIVSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNVYIILASIL
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            5570..6652
                     /locus_tag="KRN00_002685"
     CDS             5570..6652
                     /locus_tag="KRN00_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBH1828543.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            6801..6962
                     /locus_tag="KRN00_002686"
     CDS             6801..6962
                     /locus_tag="KRN00_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBH1828544.1"
                     /translation="MKQDKQNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGYRI
                     DKKKMNRPS"
     gene            7303..8571
                     /locus_tag="KRN00_002687"
     CDS             7303..8571
                     /locus_tag="KRN00_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH1828545.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            8766..9554
                     /locus_tag="KRN00_002688"
     CDS             8766..9554
                     /locus_tag="KRN00_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1828546.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSLRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            9554..10003
                     /locus_tag="KRN00_002689"
     CDS             9554..10003
                     /locus_tag="KRN00_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBH1828547.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            10007..12271
                     /locus_tag="KRN00_002690"
     CDS             10007..12271
                     /locus_tag="KRN00_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1828548.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            12411..12722
                     /locus_tag="KRN00_002691"
     CDS             12411..12722
                     /locus_tag="KRN00_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828549.1"
                     /translation="MAGNLNNMRAVNNFRGDKNILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLNTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            13008..13508
                     /locus_tag="KRN00_002692"
     CDS             13008..13508
                     /locus_tag="KRN00_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBH1828550.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            13565..14551
                     /locus_tag="KRN00_002693"
     CDS             13565..14551
                     /locus_tag="KRN00_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBH1828551.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYISFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSGKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            14601..15323
                     /locus_tag="KRN00_002694"
     CDS             14601..15323
                     /locus_tag="KRN00_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBH1828552.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            15352..17286
                     /locus_tag="KRN00_002695"
     CDS             15352..17286
                     /locus_tag="KRN00_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1828553.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMSIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            17279..>18460
                     /locus_tag="KRN00_002696"
     CDS             17279..>18460
                     /locus_tag="KRN00_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBH1828554.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKYLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIHIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GK"
BASE COUNT         7041 a         1827 c         3158 g         6434 t
ORIGIN      
        1 ttatataaat taaaataata ttcgtaaaga aaaattcatg ttttgtactg tataacatat
       61 aattttgaca atatgggtca taagtttcta ccggaatacc gtaaatattc tgactatgta
      121 tactattatt tagttaatta aatatttaat taactgaatt atgaaggata cggctcagct
      181 tatcaactac tgtgtcgttt ttttgtaaaa tttaatagga ggtgttgtta tgcaaacaac
      241 aaacagtagt actatgcaga aactttttcc aattttgact aataaaaatg tcgacatgaa
      301 gaaggaaata attgcaggag taactacttt tttaactatg gcttatataa tagctgtaaa
      361 tccaaatatt ttatctgaga caggcatgcc tgcaggtgca cttgttacag gtacttgttt
      421 agcagcagca tttggatgta ttttaatggg tgtagttgct aaccttcctt ttgctttagc
      481 atcaggtatg ggtcttaatg cattttttgc atatacagta gttttacaaa tgggtgttcc
      541 ttgggaagta gctcttacag cagtatttgt agaaggtatt atttttatag tattatcagt
      601 aagtggagtt cgtgaggctg ttgtaaatgc gataccaaaa aatatgaaat tagctgttac
      661 aggtggtata ggaatattta ttgcacttat aggtctagtt aacagtggaa ttgttattgg
      721 agaccaagcc actcttatca aaatgggtag atttacacca gcagtaataa taacttgtgt
      781 aggattaata attattgctg tattagataa aaaaagagtt aaaggttcta tactttttgg
      841 aatagtagtg agttcattac ttgcttgggc atttgctttt ataaatccag agtatgcaca
      901 aaaattaggt atatatttac ctggtggatt atttaaattc gaaagtttag caccaatagc
      961 aggtaaaata gatttaggat atgtactaca tccaacaaat ataggtggtt ttttagtagt
     1021 agtttgtaca tttttatttg ttgatttttt tgatacagta ggtacattag ttggtgtttg
     1081 ttctaaagca aacatgttag atgaaaaagg gaatgttcct aatgtaggta gagccttact
     1141 tacagatgcg gttgcaacta cagttggtgc aggacttgga gtatctacag ttacaactta
     1201 tgttgagagt tcaacaggag ttatcgcagg tggaagaact ggatggacag caataacagt
     1261 tggaatttta ttcttagctg caatgttttt ctctcctgta tttatagcaa ttccatcatg
     1321 tgctacagca ccagctttaa tatatgttgg atatttaatg cttggtacag ttaaggatat
     1381 agagtttgat aatataactg aaggtgttcc agcttttgtt actattgctt gtatggcatt
     1441 aacatatagt ataggtgatg gtttaacttt aggtatatta acttatgttt tcgtaaatat
     1501 attttataat atatttggag ctaaaaaggc agaagacaaa aaacatgttt ctgtagtaat
     1561 gattgttctg gcaatattat ttataataaa actttggcta ctataatagg tattatttaa
     1621 aattttaatt taatataaaa taaagggctg taatttatta tcaattgtga tgataaacta
     1681 cagctctttt gtatttgttg tatttttgta tttattgtat tatttaataa tgtctattag
     1741 ttctccattt tgtaaagttt taggtgtaat tactatattg aactcttttt gcaaatcttt
     1801 tataatatct aattcttttt ttgttattat tgagattgtg ttaccacttc gatttcctct
     1861 agcagttcga ccacatctat gcaggtattc atttttactt tttggaaaat ccaagttaaa
     1921 aacatgactt acatccacaa tatctagtcc acgagcagat aaatcagttg taattaaaat
     1981 ctttgcttta ccaagtttaa atttatttat tgcattcttt ctatcttctt tttccatatt
     2041 tccaaaaatt cctattgctt tgtaattatg ataatttagt tttgatacta gaacttctat
     2101 atttttttca ttatttacaa atacaatagc tttttttgga tttgtagctg ctaatgcctt
     2161 tctaagaaaa gtaaatttat cccttatctc acctaataaa tatgagtgat tgatgttagg
     2221 atttatttgt gatttttcct ttgtttttat tatttcaaac tccttcataa gtttatcaca
     2281 aatttttata gtgctatcag taagacttgc agagcatcct ataatttgtc tatctcttaa
     2341 cgttgttctt attatgtctt ctatacaagt tatatttttt ccattcaata gattgtccac
     2401 ttcatctaag acaatagttt ttatattatg tgattttagt ttcttttgtt ttatcaagtc
     2461 taaaactctt ccacaagagc caattactat gtgtggtttt actgctttta tattttttat
     2521 ttgtttttgt atattgacct ccccaattaa agctaaagaa gtaacggaga gttctgcatt
     2581 tttagccaat aattcaacct ggtttgtaat ctgcattact aattcatgcg taggtgcaag
     2641 tataagagct tgtgtttctc tttttgatgt atcaattttt tcaaatatag gtaaaaggta
     2701 tgctagtgtt tttcctgttc cagtctgtga attaatcaat aaatccttat tttgaattat
     2761 atttcctata acaagtgact gaacttctgt tggagaagtt atgtcttgtt ttttgagtcc
     2821 atctattaga atggaactta tttttagttg ttcaaatgta ttcatatttt gctccttata
     2881 ttttaataat tatagtcaac tattttttat tatacattgt ttattcaaat cgaactatat
     2941 attcttttat aattatgtgt aatttgaaag taaatatcaa ttatatttat acctttatat
     3001 ttctgatacc tttgcatttt atagatttct aaaataaaca aataaaagtt gtaattgttt
     3061 gatatttgtt atatattata tataacaaat atcaaaacta taatatggag ggaaattatg
     3121 ttaaaagtaa tcaatgtatc taaatcatat aaaaataaaa aagtagtaag tagtgtctca
     3181 tttgatgtaa atgatggaga gctttttggg tttataggac ataatggagc aggtaaaact
     3241 actactatta aagcaattgt tggaatacac gattttgaag agggagaggt actaataaat
     3301 tctaaatcta taaaaaaaca gcctgttgaa tgtaaaaagg aaatggcata tatacctgat
     3361 aatccagatt tatacgagtc attaactggt atacaatacc ttaattttat agctgacata
     3421 tttgaagttg ccaaagataa aagagaagag ttaataaaat attattcaaa taagtttgaa
     3481 ctcaataaag cattaggaga tttaatatct tcatattcgc atggtatgaa acaaaaatta
     3541 gctataattt cggctttgat acacagccca aaaatcttaa ttcttgatga accttttgta
     3601 ggtcttgacc caaaagcttc ctttatattg aaggaaatta tgagggagtt ttgtgacaaa
     3661 ggtggttgta tatttttctc aacacacgtt ttagaagttg ctgaaaaaat ttgtgataag
     3721 attgccataa taaaagatgg aaatataatt gcttatggaa ctacagaaga agttaaggga
     3781 agtaattcac ttgaaagtat tttcatggaa ttaatagaga aataaaatgt tttttataca
     3841 atatagtgtc taaagtgagg aatgataaaa tatgagcaat ctaagtatat taataaaaac
     3901 taatataata aatgaattta aattaaatgc gttaaaaaaa gctgatggta gagaaaaaca
     3961 aaaaataatg ggaatgatgc tttcagttgt tataatagcg ggtctattaa ttttttatgt
     4021 aacgagctta agtctctctt tagttgatat cttaaagcaa ataaatcaac tggaaatgct
     4081 actgatattt ggttttggat tatcaacatt aacaactatt gttacatcat tatataaaac
     4141 gtcatcatat ctatttcaag caaaagattt agaccttttg actagtttac ctataaaaga
     4201 atctactgta ctagcaagta agatattaat gttggttgga gcaaactatt tattttcttc
     4261 aatatgtatg attatacctg cagtggttta ctttttaaat tctgatgtaa gtataactta
     4321 tttcccttat ttgatattgc tatttttagc tttaccatta ttaccgatag ttgcttcatc
     4381 aataattttt ctatttatag ggcagatatc atcaagaata aaatacaaaa atttagtatt
     4441 aatcataggt agcattatat tgatgttgct ttatacccta cttatgtcaa gacttaattc
     4501 tatgtcagtt gaaatgctaa agaatagtgt gtctatttca gagacgatta gaaaagtata
     4561 tcctcctata tattattttg ttgatgctct taaaacagga agtatagttt catttttagc
     4621 atttatagcc atctcaataa taccattttt tatgtttgta actctgtttg caaaaaaatt
     4681 taaagatata aatgctaaga tgagtgaagg atataagtca aaaaattatg aatttaaggg
     4741 tcaaaaaact tcaagacctt caaaagcttt attaaaaaaa gaatttaaga gatatacttc
     4801 ttcgtttata tactttttaa attcatctgc aggtttgtta tttctaatag taggtacaat
     4861 tttaatatta ttatttggag cagataaagt gggtgagtta ctgaaattga atatagattt
     4921 taatcttata aaaatacaat tattgggagt attcttcttt ataatagtaa tgaattgtac
     4981 aacatactgt tcaatttctc ttgaaggaaa aaacttatgg atactgaaat cttctccaat
     5041 agatgaaaga gaaatattct ggtcaaaaat attgatgaat tttttattga atgccccatt
     5101 atctatttta tgtctaatat tagtatctat aagattagac tttgaaattc agtttattat
     5161 tgtatcaatc tgtttgattg taagtttttc aatgtttgta gcattgatgg gattattatc
     5221 aaatttatta tacccaaacc ttgattggaa aaatgaggtg gctgtagtaa aaagaagtgc
     5281 aagtatgata gttacaatgt tagtatcatt agcttatgta attatacttg gaggtatata
     5341 tgtattactt ggaatttcgt ttttaaacgt atatattatt ttggcaagta tacttacttt
     5401 gatattagat tttatgatat ggagaattat ttctactaaa ggagtaaaaa tatttaaaaa
     5461 tttataggtg tatttatgtc aaataaagac ttatcttttt tagtcttgca aataataggt
     5521 taagtagtat actatgtata gtgatatgaa aaaatttagg agaaaataaa tgagaaaatt
     5581 atccaaaaga gaaaaagatt ttattcaata tggattttta ttatttttga tatgtattac
     5641 tacttattta gtattaacta ctttagatat aaaactaata cctaaaatta taaggctagt
     5701 aaataagact tatatatttc ttggcatatt gacaattata gtatatatga taattgaatc
     5761 tattgtaact catttgataa taaatgcagt tcaaaaaaca aaagtaaaat ttattggtat
     5821 taaaatggct acaatgggat tttactataa cttagttact ccatttgcat ctgggagtca
     5881 accaatgcaa atatatgcac ttacaaaata tgatgtaagc cttagtaaat cagtggctat
     5941 agttactaat aaaactgtag tatttcaaag tacagttact gtattttgtg gaattttaat
     6001 tttgctaaat aagtcattac tgatggagca agtacattct gtgaaagtct tgataacttt
     6061 tggaatgatt atgaatgtaa gtatgttgtt aggtggacta ctaatagtat ttagtccaaa
     6121 acaagtaaaa atgatagcag aagttttgat taatttttta tctaaattta aaacatttaa
     6181 atttttagat tcaaaacgtg atagaataaa tcattatatt gatgattata attattctat
     6241 aaaaatattt attaaaaatg taagaatctt agttttaagt atattactta ctgtgttaca
     6301 attaatcgca tatttcagta tagtttattg tgtgtataaa gcctcaaatt taagaggagt
     6361 ttcatatgta catataatga cattacaggt ctttttatat atggctatat caccaattcc
     6421 aacaccagga aatgttggag ctaatgaggt tacatttttt actatgttct ccaatataat
     6481 tccaaaagaa ttattggggt actctgtact cttatatagt gggtttgtat actattttat
     6541 attaatagtt tcaggtttat ttacatttgg aacgcattat acattaaatt cttggaaaaa
     6601 ggaagataaa gtaaattcta atttagataa ggttattgaa aaattaaatt aataaaataa
     6661 ttagggaaat tctatatata aatatggtgt tgagtaagct atattatatt gagatatttc
     6721 ccttttttga ttaaaattat agaaatttga aataataagt aataaacaga aaaagtgata
     6781 ttgttttgaa aggagaaact atgaaacaag ataaacaaaa tgaaaaacaa agtgagattt
     6841 ctaagataaa acaaagcaat gataataaac ttgaaatagc tcaagaatta catgtaagta
     6901 aaaatatagg gaatatgctt ggatatagaa tagataagaa aaaaatgaat agaccaagtt
     6961 aatgaaaatg ttgaaaatgg tacattttaa aaaatatata taatgaaatg ttttattgtt
     7021 aaatttaaac ttattttaat gggggaaaaa gtcgaaaaat atctaaaaag atatggatat
     7081 aaaaaatatt aatatatata tactataaac ttgacaaaat caacctttta ataactagca
     7141 aaaaatagca aaattatata agcgttattt aattgtcaaa aatgaaagct aaattgcatg
     7201 tcctaaaaaa aatgattgat aacatttatt tgtgtgctat aattatatag taaaacaata
     7261 agtatattgc ataatgtatg caaatcgaga ggagagacgg acatggaagc atctatacac
     7321 acaattgcca gcaataattt attgataatt tttgctattg taagtataac tggaataatt
     7381 tgtagtaagc ttagtgaaat aataaaggtt ccagatgtag tgttatattt acttgtaggt
     7441 attttaatag gaccatcatt tttaaaattt atagatattc gtggatttca aatagaaaat
     7501 caactaatac ttacatttgg ttctgcattt attttatatt taggtggaaa agaaataagt
     7561 ttaaaagtat tgagaaatgt gaagatatct gtattcttat tagctacttt aggagttgtg
     7621 atatctgctt ttataatgca acaagtaata ggatttactt ttgggataag tgcaatgact
     7681 gctttactag caggaactat aatagcatca acagacccag ccactcttgt acctatattt
     7741 aatcaggtaa agataaagga tagggtaaaa caaactgtaa taagtgaatc agcttttaat
     7801 gatgcaacag gagctatact aacatcagca gtgttggctg taattttgtc aaataaattt
     7861 tcattaggtg aaaatattta tgaactgggg acaatggtta ttgtcggagt tttagttggt
     7921 ttaattacag gaatactgct tttgaaatta gttaatgata aaccttatgg aatatttaaa
     7981 gattttgcac caataatatc tgttatttca gttgtagttg catatgaatt atctacaaaa
     8041 ttaggtggaa gtggatatat gtcttgcttt attgtaggta taataactgg taacaagaaa
     8101 aactttaaaa tttggttaag tcaaaaatct tatgatgcag atttttatgt tgctgaaact
     8161 ttaggtacta tttgtcgtat ggcaatattt ataatattgg gtagccaagt taatttggct
     8221 cagttaagta aatattttat gccatctgta attacagtat tagtattaat gtttatagca
     8281 agaccacttt gcgttttagt ttgtacactt gtagacaggg aagcaaaatg gagtaaaagt
     8341 gaaatattat ttatgatgtg ggtaagggaa acaggcgtaa taccagcagc actttgtggt
     8401 attatttcag caatgaaagt tcctggatac gaagtgattt catctgtagt attcatgact
     8461 atactaatta cattagtaat acaaggaagt actacaaaat tagtagctaa aaaacttgga
     8521 ttattagaag aagaagtgat aaatataagt gaaaaagtat caacttttta aagttttgct
     8581 ttaaaatagt acctgttaat ggctatttta atattgtcta atgatgatta ttgaaatagt
     8641 cattttttta tgtataagta atttacagaa tttacatatt agacatattt attatcaaaa
     8701 tttgttgaag ctatgatata attagttgta tttaaaataa gaatagcaaa taagggagga
     8761 aatttatgtt tacggttatg gatattgtac agccagatac agtagaagaa gcgtactcaa
     8821 ttttaaataa aagaaaaact aaccaagtaa ttggtggaag tgctttttta agaatgggga
     8881 aaaaaagaat aggaacagga atagaattat ctaaattaaa tttagattat ataaaagagt
     8941 atgaagatta cgttgagatt ggttctatga ctacttttag aacattagaa acaagttcca
     9001 taataaaaaa taattttgga agaataatag aagattcagt taaaaatata ataggagttc
     9061 agtttagaaa tgtagtaaca gttggtgcaa cagtattttc taaatatggt ttttctgact
     9121 tgatagtagc attactttca ttagatacag aagtagaatt atataatatt gggagaatta
     9181 gtcttgaaga gtttctaaat agagattatg agaaagattt acttattaag atatacataa
     9241 agaagacaaa taagaatgct tcttataaat cacttagaaa tgcaaagagt gattatccaa
     9301 ttctaaatgt atctgtatca aaacatatgg aacaatttaa gttatgtgta ggagcaagac
     9361 cgcagaaagc tacgattgca aaacaagcta gtgaatttct atctaacaat gaaatcaatg
     9421 aaattaatat agataaagca gtagaaatag catcagaaga actaactttt ggttctaaca
     9481 tgagagcatc tagggagtat agaaaagcta tgagtaaagt acttttaaaa agagctataa
     9541 tggaggttat ttaatgttag taaagattaa tataaatggg aagaaaaaaa gtgttgatat
     9601 agaaccagaa gaatatctgg ttgatacttt aagaaaagtt ggtaatttaa gtgtgaaaag
     9661 aggttgtgac acaggctgtt gtggtttatg tacagtttta attgacaaga aacctacatt
     9721 atcctgtgca acactgacat tgagagcttt agataaagaa ataactacaa ttgaaggttt
     9781 agaaaatgaa gttaaagaat ttagtgaagt tttggtaaaa gaaggagctg agcaatgtgg
     9841 tttctgttct cctggcttta tacttactgt acttgcaatg aaggatgagc ttgaaaatcc
     9901 tacagatgat gaaataaagc attatcttac aggaaatcta tgtagatgta cagggtatat
     9961 gggacagtta agagctatca aaacttatct ggaggtaaaa tagaacatga atatagttgg
    10021 aaaaggaatc aagaaaatag atggaatgag tatcacaaca ggaaagcctg tatatacaga
    10081 tgatttatca gcaaaagatg ctttggtggt aaagatactt agaagtcctc acgcttatgc
    10141 aaaaataaaa gatatagata catcaaaggc agaaatggtt gatggtgttg aatgtgtttt
    10201 aacatataaa gatgtaccaa aatctcgatt tacacttgct ggtcaaacat atccagagcc
    10261 atctccatat gatagattaa ttcttgaaga tgttgtaaga tatgtaggtg acgaagtagc
    10321 tatagtggca gctatagatg aaaaaactgc aattaaagca atgaatctta tcaaagtaaa
    10381 gtatgaagta cttacacctg ttttggattt tgaagaggca ataggaaata aaactatggt
    10441 acatgatgaa gatagacatt gtaactttga tataggtatg caaagagaaa aaaatatagt
    10501 atcccatcat gattatacaa aaggtgatgt agaaaaagta ttaagtaatt gtgatgtagt
    10561 gattgaagaa acttattata ctcaagctca agcacatgca atgatggaga cgtatagggc
    10621 atacaattat ttagaccata tgggaagatt ggttgtagta agttcaactc aaataccatt
    10681 tcatgtaaaa agacatttat ctcgtgcact agaaatacca gctagcaaaa ttagggttat
    10741 aaaacctaga attggtggcg gatttggtgg taaacaaact gcatgtgttg agattttttc
    10801 tgcaattgtt actttaaaaa cagggaaacc agctaaaata atttatgata gaaaagaaac
    10861 ttttaattgt tcaacaagta gacatgcaat gagattaaaa gttagactag gtgctacaaa
    10921 tgatggcata ataaaggcaa tagatataaa agcactttct gatacaggag catatggaga
    10981 gcatgcttct acaactattg gtttggttgg agaaaaaact ttaccaatgt ataataaagt
    11041 tgaagcaaca agatttattg cagatgtggt atatactaat aagatgccag caggagcact
    11101 tagagggtat ggagcatcac aagggtgttt tgctgttgaa tcaactataa atatgcttgc
    11161 taataaatta aaaatggacc caacagattt aaggttaaaa aatgtggtaa cagaaggtga
    11221 aactacattt gcatatggta aaactttaaa tagtgtcgat ttaataaaat gtataaataa
    11281 aggcaaagaa cttattggat ggaatgaaaa atatccttgt aaacatcttg ataatggaaa
    11341 aattagaagt gtgggtatgg caattactat gcaaggttct ggtatacaag gtcttgataa
    11401 gtcttcagct gaaataaaat tgaatgactg tggagattat actcttatga taggttctac
    11461 tgatatgggt acaggaagtg atacgatttt agctcaaatg gctgctgagg ttcttgatac
    11521 aagcattgaa aatataacag ttatatcagc tgatactgac ttagttccat atgacccagg
    11581 ttcatatgct tcaagtacta cttatgtaac aggtatggca gtagttaagg cagctcaaga
    11641 cttaagagaa aaaataattt ctgctggagc aactaaacta ggtgttgaga aggatgaagt
    11701 agaatttgat ggtataaaat taactagtaa aaaaggtagc actttattat tcgatatagc
    11761 agttgattct acaattggtc cagatactaa tcaattaata ggtcttgctt ctcatggtag
    11821 cccagtatct cctccacctt ttatagcagg ttttgcagaa actgaaattg atacagaaac
    11881 tggaaaagtt gatttagtaa attatgtagc tgtagtagat tgtggaacgg ttataaataa
    11941 aaatctagct aagatacaag ttgaaggtgg aattgttcaa gggattggaa tggcattatt
    12001 tgaagaagtt agatacacag aaaaaggaag catggacaca aatacattta tgcaatacaa
    12061 gattccagct agatgtgata ttggaaatgt taaagtagat tttgttgaaa cttatgaacc
    12121 aactggacca tttggtgcta aatctgttgg agaagttgtt ataaatacac ctttaccagc
    12181 aatacaagaa gctgtgttta atggaattgg tgtaagaata aatacactcc ctattacacc
    12241 tgaaaaagtt tttatggaaa tgaataaata attatttatg aaaatttaga ctagttttac
    12301 atgttaaaca accagttatg tcatacctgt tgaaagatat ttaataagta gttattataa
    12361 tattatgaat tttacttata aaatacaaaa ttaaataagg ggatgatgtt ttggctggta
    12421 atctaaataa tatgagagca gtaaataatt ttagaggaga taagaacatt ttagaatgtt
    12481 tagtcagctt tgagggtcgt tcaataagtc agagaaaagt aagggtattt tttaaagaaa
    12541 aacaaaatca aatagaaatt gattttgcag aagaggaaat ttctaaattg gttgaaaatg
    12601 ttgttttaaa tacatcatat caagaaatgt tatatgatga aatagagaaa caactggaaa
    12661 ttgattgtat aggtacttgg atgatattat ctaaattaaa agatggtagt agagttcact
    12721 gattttaaaa taaattatta gagcctaatt ttaaggctct tttttgctgt ttttaattaa
    12781 caatagaaaa tttatcttta gtttgtatat aattttaata tcatatattc tatatatata
    12841 aaattgaatt tgtatgtatt atgttgtata atataaaatg aattaggaaa atagttcgct
    12901 aaaataattt gtttttataa aattactgtt taagtttata gattttgtat aaaataaagt
    12961 tatgttatta atttttttag aaataaaact tttactagga gacagatatg agaaaaaata
    13021 gtattaatat agcactaact gcagcaatta cagcaatcta tgcagtttta acattatcat
    13081 tgggatttat aagttatgga ccaatacaat ttagggtagc agagattatg atgcttttgg
    13141 catttttaga taaaggatat atagtaggtc ttacattagg ttgtttttta gcaaatgtaa
    13201 taggaccata tggtgtacct gatataattt ttggaacatt agccacattt ataagtgcaa
    13261 gtatgattta tattactaga aagttaggta aacagaataa aagtacttta gttatagctt
    13321 ctttatggcc aactgttata aattcgattg tggttggtct aatgttaaat gtattctttg
    13381 ggcttccatt aattctatct atgatacaag taggttttgg agaatttgta gtagtaacaa
    13441 ttgtaggagt accatttttc tgctttttaa tgaaaaaata taaaaatgtc attaatatta
    13501 aattttaaat agtgtatagt aatttaatta attgagagta ttattagtga aaagaggtgt
    13561 ttatttgtcg aaggtaaaaa gattgactga tgtttggata tatattaatg ataagcaaaa
    13621 gtttacaata aaagagttgt cagaggaatt taatctttca gctaaaacaa tacaacgata
    13681 tttaaaagaa ttaaataaaa tgggacttcc aattcaagca gaacaaggta gaaatggagg
    13741 ttatagggtg ctaaataata gctatatacc tcctgttata tttacagaaa aagaagttat
    13801 gattatacta tttgcactta agtcacttca gatttataat tataagttaa tggaaataga
    13861 aattaattct ataatgagaa aagtaagtta tgaacgtaaa agcagtataa aagtaggtat
    13921 agaaaatatt aaaagataca ttagctttgt agctaatgat actaatgatg gagattttaa
    13981 gagtagtaat gtaactgagt tttttagagc ttcttcagaa tctctaattt taaatattaa
    14041 gtataagtgt ggtaatcaga ttttggaaaa aaacgtatgc cctataggta tatatttaaa
    14101 taagggagca tggttttcac cagcatatga ttgtaaaagt ggtaaaataa tattagttca
    14161 tatagataat ataattgata taaaaagaac aggagaaagt aaaaaaatac atataaactt
    14221 ggaagaatgg ttacatgaag tatataacaa tttatatgga aatagttcaa ctactaaaaa
    14281 atttggtgaa attatttatc taaatgtatt attaactaaa gaaggtgttt ctaaaataaa
    14341 ggacagttct tggaatttag atatggagct aaatgaagat ggtagtggaa taattagtac
    14401 attcataaag gttgaagata tagattgtta tgcttcgatt ttatttttta ttggaaataa
    14461 tgctaaggtt atagagccaa aatttttgaa taagctactt tatgataagg ccaatgagtt
    14521 aagatatttt tatgaagaaa atatggtata atatttagaa atgttgaaat taaataatta
    14581 ttaaggagat atacgttata atggaaaatt ttaataagaa tgctaaaata attggtattg
    14641 gagctgaagg tattaatata ataaatgaag tagaagaaaa aataaaagca aatatggata
    14701 tagaaaaaat aaacataaat caagagattg aaaaagaata tgttagaagt cttttagatg
    14761 gtgtagatat attatttttg atatattcat ctgaagataa acatattaga gatattataa
    14821 aagctgtttc atatatgtca aacgaaagaa gagttctatc tataggaatg gattgttcag
    14881 agaaagaaaa taaagaagat ttagagcttg ggagagagtt taaaatcaat aatgatagta
    14941 tatttaaatt tgttgattta atgaatatca tggtagagtc tatttctgat tcttgcatga
    15001 taaatataga tattactgat ttaaaagaag ctattgtagg agataaagga attaagtatt
    15061 cttttgaaga gtttgaagat acaaagtcat atagcgagat agctgacatt ttatttgaca
    15121 ggatggaata tattggtgag gaatttataa gtaagaaagg aattgtattt gttgaaggaa
    15181 gtccagaatt ttctataatg gaattgaatg atttaataag taatattcag agcaaggtag
    15241 aagaaagcta tgaagtaata ttttctttat atataaagga aaatttaaat ggaaatatta
    15301 gagtaggctt attgtataat tagtatattt tagatattaa ggagagtgta tatgtctgaa
    15361 aatataagag gtacagagta ttggttaatg gaagaatttt tttatcagga aacagacaca
    15421 ccacagattt ttagagaaga aagcataatt gcacttggat ttgatataaa aataaattta
    15481 aaaaaagtat ttagtatggg gaaaaaatca gaaaagtata ttaatgagaa ttgtaatgat
    15541 aaagatttta taaaaaagtt tatgtcgatt aaaaaaggag attatttttt atataaagca
    15601 tatcaaaata tagaagaaaa agttaaatgt aatgtgtcta ttggcatagt tgaagaagat
    15661 tttgaaaatg gatatgaatt aagtcatatt ttagggcata cactaccagt aaaatggatg
    15721 cataattttg atacagtttc aaattgtaaa gtatatacaa gtgaatttta taaattaaat
    15781 aataatgata ttagctcata tttagaaatt attaagtcac aagataagaa attattgaga
    15841 aaaagaatag aagaaagtga aaataataaa tggtatttaa aaaactatta ttataaaaat
    15901 gtagataagt gtgtagatga tgaagaatta tttattcagc ccattaatct agaacaatta
    15961 gaaagtctaa aaaatataaa gacagatgat tatattttat tgtataatag cgagaaagta
    16021 atttgtgaaa atgaccatac aatgaagagt ctatttggcg tatgtcaagt tatggaaggg
    16081 ttcgataaag agaaagtaag tgctttggag ggtggatatt tttttcctgt tagatggata
    16141 gagtatgaaa aggagaatat agacggaaat gcatgggtta tatttgaaaa taatagtata
    16201 gttgaaaagt atgtaaaaag atttactaat aaaatgccat taaatactat actttatgga
    16261 ccaccaggaa ctggtaaaac atacaataca aaacagatgg tttacaatct agtaagtgaa
    16321 accagtctaa gaaacagata ctatacaggt tacttagatt ataaaaacaa tgtagaattt
    16381 tgtacatttc atcaatcata tggatatgag gaatttatag agggtcttaa gtctgatggt
    16441 gaaggcaatt ttaagccaga agatgggata ttaaaggata tatctataga agcatgttat
    16501 aatgcattga aatttgaaaa aaagatgagc tttgagttgg aaaaagatag cttgacttta
    16561 gaaactataa aagacaggaa aaagaaatta gtattagaaa atatagaata tagtgagagt
    16621 tttaattttg aagaatcaga aaactatgtt ttaataatag atgaaattaa tagagggaat
    16681 gtatctaaaa tatttggtga gctaataaca ttattggaag atgataaaag acttactaaa
    16741 tcaaatcaaa ctattgtcaa actaccatat tcaaaggaaa aattttctct acctccaaat
    16801 ttgtatatag ttggaactat gaacacatca gataaatcaa tagcactttt agatatagct
    16861 ttaagaagaa ggtttaattt tgaagaaatt atgccagatt atgatttatt gtctattgta
    16921 gatggtatag atattagaaa aatgctatat acaatcaata aaaggataga gtttttatat
    16981 gatagagacc atgttattgg acaagcttat ctacttgctg tagaaaatat taatgatata
    17041 gtagtagtat ttagaagtaa aataatacca cttcttcaag agtattttta ttatgattca
    17101 gaaaaagtag gtttgatttt aggaggaatt ggaagaaatg aaaaagataa atacattgtt
    17161 tataaagaaa aacttatagc ttctgagtta tttaaaaata ataatgcctc aataatggag
    17221 agtaaagtta actattgtat aaaacaaaac atatctagtg aggagctaaa aaatatatat
    17281 gagtaaaaat atatatgtta aggaaaccta tgaatggata agggtaggta atggtgaaaa
    17341 tgagcttaca gaaattgaat atgaaaaatt gcttaaatat ctagagaaca ataatgatgt
    17401 attaaaaagt aatataatag atattaaata caaaaaactt agatttataa actatgtagg
    17461 catcatatgt tttgaaaatg taatacttga aatacttcct aaattgtcat taagtgataa
    17521 tcttgtaaaa gatagagaga tactattaca gatgctttct atatgtaata aaattccaat
    17581 tacaatgaat gaaaaaataa gattgagttt gaaaaattat aatctcttaa atttttttgt
    17641 tatgtatttc attgagagta tgcaaacaca gatgaaaaaa ggtatttatt ttgaatatat
    17701 aaataaaata gagaacttaa atgttatgag gggtaaaata ttattaagta catatgcaaa
    17761 agaaaaaggc atttctccaa tgaaaataag atgtgaatat gatgagtata gtgaaaataa
    17821 tttcttgaat caagttctta aaaaagcatg tatatctatt ttatgtagaa taaatgacaa
    17881 ttcaattcaa ggcaagatta aaaaaatttt aagctatttt caaaatgtag atttaattca
    17941 tatagataga aaaaaactgt tggattataa attttataaa aacaatgata gatttaaaga
    18001 ttgttattta ctagctagac ttctactttt aaatttgtct atggataata gtcaaaataa
    18061 tcaagaggca ttttctatat tatttgaaat aaatactttg tatgaagaat atataggaat
    18121 tttaatcaaa agtatatggg acaattcatt tagagaaaca tatatacaag ataagagtaa
    18181 atttcttttg aaaaatgaac aaacaggtaa gaaaaacttt aatttaagac cggatatagt
    18241 tttatatgac ttaaaaaatg aatatgaaat tataattgac actaaatgga aagctattga
    18301 agtagattca aatgtttttt ataggtcaag tgatatatac cagatgtatg catatataac
    18361 agcatatgaa aatgcaaaaa gatgtatatt attatatcct tgtattcaaa aagataagaa
    18421 ttatagttcc tggaaattat cagaatcatt taagggtaag
//
LOCUS       DAEQAF010000075        18135 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.078, whole genome shotgun sequence.
ACCESSION   DAEQAF010000075 DAEQAF010000000
VERSION     DAEQAF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18135
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.078"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            121..1572
                     /locus_tag="KRN00_002697"
     CDS             121..1572
                     /locus_tag="KRN00_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBH1828555.1"
                     /translation="MDFFNGILTSINNAVVYVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(1792..2253)
                     /locus_tag="KRN00_002698"
     CDS             complement(1792..2253)
                     /locus_tag="KRN00_002698"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBH1828556.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLN"
     gene            complement(2358..3551)
                     /locus_tag="KRN00_002699"
     CDS             complement(2358..3551)
                     /locus_tag="KRN00_002699"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBH1828557.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(3574..4239)
                     /locus_tag="KRN00_002700"
     CDS             complement(3574..4239)
                     /locus_tag="KRN00_002700"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBH1828558.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(4273..5385)
                     /gene="ribD"
                     /locus_tag="KRN00_002701"
     CDS             complement(4273..5385)
                     /gene="ribD"
                     /locus_tag="KRN00_002701"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBH1828559.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIIKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(5517..5638)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            5827..8310
                     /gene="recQ"
                     /locus_tag="KRN00_002702"
     CDS             5827..8310
                     /gene="recQ"
                     /locus_tag="KRN00_002702"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBH1828560.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMSDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFVNTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      8399..8510
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8652..9953
                     /gene="thiC"
                     /locus_tag="KRN00_002703"
     CDS             8652..9953
                     /gene="thiC"
                     /locus_tag="KRN00_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBH1828561.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            10007..10201
                     /gene="thiS"
                     /locus_tag="KRN00_002704"
     CDS             10007..10201
                     /gene="thiS"
                     /locus_tag="KRN00_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBH1828562.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            10194..10997
                     /gene="thiF"
                     /locus_tag="KRN00_002705"
     CDS             10194..10997
                     /gene="thiF"
                     /locus_tag="KRN00_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBH1828563.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLCENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGEGLMAPRVAICANHMANLATQILIDM"
     gene            11060..11830
                     /locus_tag="KRN00_002706"
     CDS             11060..11830
                     /locus_tag="KRN00_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBH1828564.1"
                     /translation="MDKLILGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLCNL"
     gene            11847..12950
                     /gene="thiH"
                     /locus_tag="KRN00_002707"
     CDS             11847..12950
                     /gene="thiH"
                     /locus_tag="KRN00_002707"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBH1828565.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            12951..13640
                     /locus_tag="KRN00_002708"
     CDS             12951..13640
                     /locus_tag="KRN00_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBH1828566.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            13828..15222
                     /gene="yfcC"
                     /locus_tag="KRN00_002709"
     CDS             13828..15222
                     /gene="yfcC"
                     /locus_tag="KRN00_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBH1828567.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            15739..17106
                     /locus_tag="KRN00_002710"
     CDS             15739..17106
                     /locus_tag="KRN00_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBH1828568.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            17131..17739
                     /locus_tag="KRN00_002711"
     CDS             17131..17739
                     /locus_tag="KRN00_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBH1828569.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMNDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYEKLTKV"
     gene            17787..>18135
                     /locus_tag="KRN00_002712"
     CDS             17787..>18135
                     /locus_tag="KRN00_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBH1828570.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLS"
BASE COUNT         6874 a         2035 c         3077 g         6149 t
ORIGIN      
        1 tgtaatttga ttttataaat attataatta aattaatgaa tttttaacaa ggaattattc
       61 atttttttga ttttaagatt tattgagaaa acaaaactaa ataggggggt aattaatata
      121 atggattttt tcaatggtat tttaacgagt attaacaatg cagtagtata tgtaaacaat
      181 tacttatggt cgtatatctt aattataatg ttagttgtaa ttggtattta ctttactatt
      241 aaaacaaatt ttgtacaatt cagatatttt atagaaatgt ttagacttct gggtgatggt
      301 acagcgaata aaaatgcaaa aaaggaagga aaaatctctt catttcaagc attttgtata
      361 agtacatctt caagagttgg aactggaaat atagctggaa tagcaattgc agtggtagca
      421 ggaggacctg gtgctgtatt ttggatgtgg cttatagcat taattggttc tgcatcaagc
      481 tttgttgaga gtacattagc tcagatttac aaagtgaaag atggtcaagc ttttagaggt
      541 ggaccagcgt attatatgga acaaggtcta aataaaaaat ggatgggtat tttattctca
      601 atacttataa ctatatgtta tggttttgta tttaatgcag ttcaagcaaa tactgtttca
      661 cttgcattta ataatgcatt tggaataagt aaaatggcta tgggaatagg tcttggaatt
      721 ttaactgcaa tagttatttt tggtggagtg catagagttg caaaagtttc tgaaataata
      781 gttcctgtat ttgcaggatt atatatatta gttgctttgg ctatagttgt aatgaatata
      841 acagagatac caagtgttat agcattgata gttgaaagtg catttgattt taaaggaatg
      901 gcgattggta catttatggg agttgtaatg actggagtga agagaggtct attttctaat
      961 gaagcaggta tgggtagtgc tcctaatgct gctgcaacag cacatgtaac tcatcctgta
     1021 aaacaaggtt taattcaatc tttaggtgtt tttacagata ctataataat atgtagttgt
     1081 acagcattca tggtattatt atattcaggt tatagtagta gtggagcaac tggaattgaa
     1141 ttagctcaag aagctttaac tcatcatata ggaccagttg gaaatatatt tatagcagtt
     1201 tgtatattct tgtttgcatt tagttctata gttggtaatt actattatgg tgaatcaaat
     1261 atggagttta tgagtggaag taagactaaa cttaatgtat ttagagtttt tgttgtaggt
     1321 atggttttat ttggttcact tactcaagta gatgtagttt ggaatcttgc agacttattt
     1381 atggcattga tggcgataat aaacttaata gcaatagcac ttttaggaaa atatgcattt
     1441 attgctttaa aagattatac aagtcaaaaa aaatcaggaa taaaagaccc tgtgtttatt
     1501 gcagatgaaa tagaaggcct agaaaaggta tcagagtggc atagggaatt atctgaggaa
     1561 catttaggat aaaaaatagt ataaaattat aaaaccattt tgaaagacta gagtatgtat
     1621 atactttata tgaatataat attgaattaa tttatattac tggaattttt aattccagta
     1681 atattttttt attatataat ttagctttat taaaagtttt tattattaaa aatagcttat
     1741 ttatcgtaaa gtgaatgata ttgggttttt aattattatg aatgttagta tttaatttaa
     1801 agacttaaat aaatttgcca tttctagcgc attcatagca caatcataac ctttatttcc
     1861 agcttttgta cctgctcttt caatagcttg ttcaatattt tctgtagtta cgattccaaa
     1921 tataacaggt aattcactgt ctaaagatac tttggctatc cctttagaga cttcactaca
     1981 tacataatca taatgagaag tagcccctct tataacacag cctaaacaga ttatagcatc
     2041 atacttacca cttttagcca ttttttgagc aacaagagga atctcaaaag ctccaggtac
     2101 ccaaactatt tctatatttt ctggagaaac gtcatgtctt aaaagacagt cttcagctcc
     2161 tgataaaagt tttgatgtta taaattcatt aaaacgagaa tttattatac ctatttttaa
     2221 atcttttcca ataagttttc cttcatatat catttttatt tcctccaatt ttatttatgt
     2281 tatagattta tatttataaa tatctttaat ttaattataa aaaactactt agtagaaaaa
     2341 tatcatcata taatcattta tataatatct aaaagatgtc ccattttatc ttttttagtt
     2401 tttaaatata gcttattaaa gtcattaatt tcttcattaa tagggattct attttcgatt
     2461 tttattccat atttctctaa ttgatttatt ttatctgggt tattacttaa aagatttata
     2521 ctttttatgt ttaaattttt taatatttga gcagccatat agaaatctct catatcttct
     2581 tcaaatccaa gcattaaatt tgcttcaaca gtatcgtaac cttcttcttg aagtttataa
     2641 gccttaattt tatttaaaag accaatacct ctaccttctt gcttcatata aattaaaact
     2701 ccacttccat tttccacaat tttcttcata gaagattcta gctgtaatcc acaatcacat
     2761 tttagagagt ggaacacatc tcctgttaaa cattcagaat gaagtctaac tagagtattt
     2821 tctatattta tatttccata agtaagggca atgtgttctt catttgaata agtatctcta
     2881 tatcctatga tttcaaaatt tccatatttt gtcggaagga aagcactaga tactttttct
     2941 atagtagttt catttatttt gcggtattct ataaggtctt ttatagtgat gatttttaaa
     3001 ttatgctttt ctttgaaaat cattaaatca tcaactcttg ccattgtacc atcatctttc
     3061 attatttcac agataagacc aatctcttta aaacctgcaa gtctagcaag gtctactgag
     3121 gcttctgtat gtccatccct gacaagaacc ccaccagttt ttgctattaa aggaaagatg
     3181 tgaccaggcg ttttgaaatc tttacttgta gaattttcat cacagaacaa ttttacagtt
     3241 tcagctcttt catatgcaga tataccagtt agagtatctg ctccatctat agtaacagta
     3301 aaggctgttt gaaatgtatc tgtattttct ctaaccataa gaggtatatt aagactttta
     3361 aatttttttt cagtggcagg tagacaaatt agacctctac catatgtagc cataaaattt
     3421 attgattcag gagtagccat ttcagctgcc atcaataaat ctccttcatt ctctctactt
     3481 tcatcatcaa ctacgattac cattttccca ttttttatat cttcaatagc ttcttcaata
     3541 gtattaaaca tgtaattcac tcctttatta tttttaaaaa ccatttttaa ataaaaaatc
     3601 tttatctata tttgatttat ggttactact attagaattt aattccttgt agttattagc
     3661 cataaaatta ttaacatact ttccaattac atcgctttct aaattaacga aatctccaac
     3721 attctttgtc aagagaatag tgttaatttt agtatgaggt ataatagaaa ccttaaatat
     3781 ttcatcatct aaatatgata tagttaaact tacaccatca atagcaacag aacctttgag
     3841 tatcattgag gataaaagtt ttttatcagg tcgtatactt actaaaactg cattttcatc
     3901 tttttcaaat ttgcagatag ttcctttacc atcaacatga cctgttacta tatgaccacc
     3961 aaatcttgaa gaaagactca tagctctttc aagattcacc ttgtcatttg catttaataa
     4021 acctaaattt gtggaacgaa ttgtctccat cataacatcg gctgtaaatt cattttttcc
     4081 gaggtttgaa acagttagac aaactccatt tacggctata ctatctccaa gatttgtgcc
     4141 atctaatatt ttatttgata gtatggttac ttttccactc ttaccattag cagtaatttt
     4201 tctaagtatt ccaacttctt ctactatgcc agtaaacatc ctaacctcct atatgaatgt
     4261 attaacaaaa atttaattta aaacatctga ttctataaga atatcgccat ctatcaaagt
     4321 tacattattg attgttaact gtgttgaatc tgacaaatga tttattcctt ctccagaaac
     4381 gaatgtagga gcatctttac cacctataat cttgggtgat agaaataatt tgaccttatc
     4441 aactaactta tttctaaaga gactgtcatt gagagtagca ccaccttcaa ctagaacaga
     4501 atcaatgttt aactctccta atttatacat tacaaactcc aaatctacta agttgttttt
     4561 tgaaggagaa attattgttt caacattatt ttcttttaac atagataatt ttatactttc
     4621 tttgcaacat gtgaaaacta tagttttact ggttttatct ttaaccaaat tactattaag
     4681 tggcaacttt aggtgtgtat ctattactat tcttgtagga tgagacactt tttcttgatt
     4741 gagcctacaa gttagtaaag gattatcgtt caaaactgta tttatgccaa ccattatact
     4801 ttggtattta tttctgtatt tatgagttag ataccttgat gattcattag atatccattt
     4861 tgattctagt gattttgtag caattttacc atctagactt actgctgatt ttataataca
     4921 aagaggtctt ttgtttttta tatgataaaa aaatgcctca tttaaatctc ttgcttcatc
     4981 ttctaatatt cccacagtaa catcaatatt gttatctttt aattttttta ctccattacc
     5041 acaaacaagt ggatttgggt ctaatgtaga tattacaact ctcttaatct tattttgtat
     5101 aattttatct acacaaggag gcgttttccc ataatgagaa catggttcta agtttacata
     5161 aagagtagag tcttttagac tttgtttagc actgtttata gcatttactt cagcatgatt
     5221 agagccaaat ttctcatgat atcctttgcc tattatatta ctatctttaa caattacaca
     5281 cccaactaat ggatttggat ttacaaagcc ttctccattt ttagccaatt caatagcttt
     5341 tttcatataa taaatatctt tttctttttg attcacaaaa ttcacaatat gtacacctcc
     5401 tgtttaattg gataattttt aaacaaaaaa ccctgagaat taactcaggg tttagaataa
     5461 tctacaataa atgtttaata aatgtagaac aaaattgctc tacaaaaaca ctcattaaat
     5521 atcttcttcc atccagactt tactgtcggc tttggaattt aaccaaatca accaagtttt
     5581 accttggctc gcgggctata ccgccgattg ggaatttcac cctaccccga agattaagta
     5641 ttaaatttat atttagaatg tatcataaat tattttactt tgcaaactat ttttttaaaa
     5701 aatatatgtt aatatataat atagaatgtc tataaacttt gaaataccac gattgtgaat
     5761 ataaaaataa aaatttgaac ataatcagga aagaagtcta attaatttaa attaggagag
     5821 taatatatga ataaaaaact tttagaaata ctatcaaaat actatggata tacaagtttt
     5881 agaaaaggtc aagaatctat aataaactct atcttaagcg aaaaagatgt gttagctatt
     5941 atgccaacag gagggggaaa atcaatatgt tatcaaattc cagctttgat tttagatgga
     6001 atgacaatag taatttctcc acttatatca cttatgaaag accaagtaga tgccttaaag
     6061 actatgggaa ttagtgctgc ttttataaat agttcattaa gtagcaaaga atttaatgaa
     6121 atattaaata atattagaaa aaataattat aaaatactct atattgctcc agagagatta
     6181 gatgcacaag agtttattga gctaataaat aataacaatg taagtcaagt tgcgatagat
     6241 gaagcacatt gtgtatctca atgggggcat gattttaggt tgagttatag aaggatttct
     6301 gattttataa aaaatttgcc taaaagacct atagttacag catttactgc aacagcttca
     6361 gaagaggtaa gaactgatat aataaattta ctgtgtttag aaaatccaga ttattatata
     6421 actggatttg atagagagaa tttatcaata aatatagtaa aatcatctag taaaaataag
     6481 tatattttag attatattca aaatcataaa aatgagtctg gaattatata tgttgcaact
     6541 agaaaggaag ttgaaaatat atataatggt ttatctaaga gaaatatatc tgtatcaaaa
     6601 tatcatgcag gtttatctaa aaatgaaaga agtaaaaatc aagaagattt tataaatgat
     6661 aatgtggata taatggtagc aacaaatgca tttggaatgg gtattgataa acctaatata
     6721 agatgggtta tacattacaa tatgcctcaa agtatagaaa actactatca agaaataggt
     6781 agagctggta gggatggaga aaaaagtgag tgtgtacttt tattttctcc aggagatgta
     6841 catatacaaa aatatttaat tgatattgga gttgaaaatc ctgaaagaaa attatttcag
     6901 cataagaagc ttcaatacat gagtgactta gtttacagta attcatgcta tagaaagaca
     6961 atattgagtt attttggaga aaattatata gacaattgca ataattgtag caattgttta
     7021 gtagagggtg aaatagtaga taaaactata gatgcacaaa aagtcatttc atgtgtagct
     7081 agaatgaaaa gaagttatgg tgttactact attgtagatg tgcttagagg ttctaagaat
     7141 aaaaagattt tacagcttgg attaaatact ttgtctacat ataacattat gagagattat
     7201 tctagtgaag acttaaagaa ttttgtaaat acattggttt ctcatggttt tttagattta
     7261 gttgagactc taggcaatgg aaatagaggt agttttccta ctataagatt aaatgagatg
     7321 tctatgaaag ttttaaaagg tgaagtgaaa gtagagttta aagaaattgt tatgacaaaa
     7381 tcattggaag tagaggatga gttatataat gctttaagag aacttagaca ttcaattgca
     7441 agtgaagaaa ggatagctcc atatatggta tttggagatg gtacacttag agccatgtct
     7501 agtagttatc caattaataa agaagaaatg ctagatatct ctggagtagg agaaattaaa
     7561 tatcaaaaat atggtagaga ttttgaagca gtaattaaag aatatgtcga aaaaaataat
     7621 ataaataaaa aaatagatga aaaaaatgtc gattcaaaga acgttaatag tgatttctta
     7681 gaggttaata cagataaagt tttatatgaa aaactgttag tcattagaga agaatatgca
     7741 acaaaggaaa aattacctgc atatatgatt ttagccaata aggctttgaa agaaataagt
     7801 ggaagatatc cacttgatga agaacaatta aaagatattt ctggcatagg tggagtaaaa
     7861 tttgaaaaat atggagctag tattttggca gaggttaata aatatgtaaa agaaaataat
     7921 attaatgtta tttgggagaa aaagggcaaa aggaagttaa tattagatgg agaaagtaga
     7981 aaaaataatg aaatagcatt agatttgcta aatcaaggaa aagatataca aagtatcagt
     8041 caagaaatag aagtttcact gtcaactatt attggatatg tgcatgacta tgtaaaggat
     8101 ggacatagta tatcatttga attaggacta gaaaattttt ataatgaaga taaaaagaag
     8161 atgattttag aagtttgcga aaaagttggc tatgataatt taaataacat aaaaagaaaa
     8221 cttccagatt caataaagta tgaaaatata agagctgtga tacttgactc ttatcttgaa
     8281 aacttaaaaa ataatattat agcagagtaa tttttaactt aataaaaaat aaaatttgta
     8341 ttattgtgtt gaactaataa ttttgctgtg ttatactgaa tttgtaaaaa taatgaaaaa
     8401 ttagagctag gggcgctaga attggctagc tgagagataa agccgtaact tacaaaccct
     8461 aataacctga tcaagataat gcttgcgaag ggaagctttt taatataatt ttattatata
     8521 aataggcaaa ttattcaatg ttaggagaaa tttgtctaag tgtatatacg attataagag
     8581 tgctttccaa acgaggaaaa gcactttttt tattttcaaa aactataact ttaatcttgg
     8641 aggattgtaa tatgaactat acaacacaaa tggatgctgc tagaaaaggc ataataacta
     8701 aagaaatgga aatcgtttct caaaaagaac aggtagatgt aaatgaatta agagaattaa
     8761 tagcaaatgg acaagttgtt ataccagcta ataaaaatca taaatcttta agtgcagaag
     8821 gtgtaggtaa aaatttaaga acaaaaataa atgtaaatct aggaatttca agagattgta
     8881 aggatataga aaaagaactt gaaaaagtta gagtagcaat agacatgaaa gctgaagcta
     8941 taatggattt aagtaattat ggcaaaacta gagaatttag agaaaaggtt gttgaaatgt
     9001 cacctgcaat gataggttca gtacctatgt atgatgcagt aggatatttg gaaaaagaat
     9061 taaaagatat aacagaagaa gagtttttaa atgtaataag acaacatgct attgatggag
     9121 tagactttat tactatacat gcaggtctta caagaagtgt ttgccaaaaa ataaaaaatc
     9181 atgagagatt gactcatata gtatctcgtg gaggttcttt attgtttgca tggatggaat
     9241 taaataataa ggaaaatcct atttatacta attttgataa aatattggat atatgtgaag
     9301 aatatgatgt tacattgagt ttaggagatg cttgtagacc aggttgtata aaggattcta
     9361 ctgatggtgt tcaaattcaa gaacttgtag tattaggtga acttactaaa agagcatggg
     9421 aaagaaatgt acaagtaatg atagaaggtc ctggacacat ggctattgat gaaatagaag
     9481 caaatgtagt attagaaaag agattatgcc atggagcacc tttttatgtt cttggaccat
     9541 tggttacaga tatagcacca ggttatgacc atataacaag tgcaatagga ggagctttag
     9601 catgtgccaa aggagtagat tttttatgtt atgtaactcc agcagaacat ttaagattgc
     9661 ctaatttaga tgatatgaaa gagggtataa tagctgcaaa gatagctgct catgcaggag
     9721 atatagctaa aaatgttaaa ggtgctcgtg aatgggataa taagatgagt aaagctagag
     9781 ctgatttaga ctggtgtgag atgtttagac ttgcaataga ccctgaaaaa gctaagagat
     9841 acagagatga atcaactcct actcatgagg atagttgtac tatgtgtgga aaaatgtgct
     9901 caatgagaac agttaagaaa atattaaaca atgaggaact taatctaata taatttttgg
     9961 ctagtatgac tggaataaaa agaagctgaa aagaggaggt gatttagtga aggttaatgg
    10021 gaaggaaatt gaatttgaaa aagatttgac tgttatagat ttattaaata aatataattt
    10081 aaaaagtgat agagttgtag ttgaagtgaa tttagagata attgaagaat ctaactacaa
    10141 tacatatgta ttaaaagacg aggacattgt agagcttatt agctttattg gaggtggtta
    10201 aaataaaaat atttgtaaat gaattattaa cagatgttga ggaaaataca actgcttata
    10261 aagttagaga tagctataac aataaatgtg atgtattggt gttaaatgga tatccaatta
    10321 aaacagatat gcccctttgt gaaaatgata aattaacact tatacaaaaa ggagttaagc
    10381 catcacttga tgaattagaa agcttgttga ttgctagaca tactccaaat atacataata
    10441 aattaaaaaa agggaaagtt gctatattgg gattgggggg acttggttcc aatatagcta
    10501 tctctttagc tagaatagga gtgggagaac ttttacttat agattatgat gttgtagaac
    10561 catctaattt aaatagacag cagtatttta tagatgatat aggaaaacta aaaactgatg
    10621 ccatgataga aaatataaaa aaaataaatc catttataaa attaaataaa cgagatattt
    10681 ttttaaacaa gaacaatatg gatactatta aggattcaga tttaataatt gaggcctttg
    10741 atgatgcttc atgtaaagca caggtatgta attatgtatt aataaattta aaagataaat
    10801 atttaatagc atcatctggt atggcaggtt actatgattc aaatataata actactaaga
    10861 agataaaaga caggttttat atatgtgggg attttgtgaa tgaagctaaa tttggtgaag
    10921 ggcttatggc tccaagggtt gccatctgcg caaatcatat ggcaaatttg gcaacgcaaa
    10981 tacttataga tatgtaaata ttaaaattag atataaaaaa gattgaatat taaaaaaatt
    11041 taatgtggag ggaaataata tggataaatt gatacttggt ggacatgaat ttaatagcag
    11101 attattggtt ggaacaggta aatatggttc aaataatata ttgcctgagg taataaaaga
    11161 aagtggaagt gaaataataa caatggcact tagaagagtg gatttagaca ataaacaaga
    11221 aaacatatta acgtatattc caaaagagat gacaatactt ccaaatacat caggagctac
    11281 taatgcagaa gaagctgtaa gaatagctag aatatctaga aaaatgggat gtggagattt
    11341 tataaaaata gaagtaatat cagatactag atatttactt cctgataatg aagaaactat
    11401 aaaagctaca aagatacttg ctgatgaggg gtttatagtt cttccatata tgacaccaga
    11461 cctttatgct ggaagaagac ttatagaagc taatgcagca gcagttatgc cacttggagc
    11521 tccaattggt tcaaatagag gtcttcaaat gaaagaaatg ataagaataa tgatagatga
    11581 gttggatata ccaataatag tagatgcagg tattggaaaa ccatctcaag ctatggaggc
    11641 tatggaaatg ggagctgatg cagtacttgt caacactgct atagcttcag caggagaccc
    11701 tgtacaaatg gctagagcat ttaaattagc tgtagaaggt ggaagggaag catatattgc
    11761 aaaaacagga aatgtgtcag aatttgcaaa tgcatcttct cctttaacag gttttttatg
    11821 caatttatag aaagtggtga ttggtgatga gtttttatga tgtaatagaa aaatataggg
    11881 attttgattt tgatggatat ttaaataatg ttactgataa tgatgtttta agaagtttat
    11941 caaaagacaa gcttgaagat tttgatatat taaatttgct ttctaaaact gcagtaaaac
    12001 atttagaaga tatggcacaa aaagcacata aattaagtgt tcaatacttt ggtaaaacag
    12061 tatgtttata tacaccaatg tatatagcaa attattgtgt taatcaatgt gtttattgta
    12121 gctataatat aaagagtgga ataaaaagaa aaaaattaac tatggatgaa attagagaag
    12181 agggagaagc aatttcaaaa gaaggtttca aacatctact tgttttgact ggagaaagta
    12241 gttttcactc aagtgtagaa tatataggtg aggctataga aatattaaga gagaaatttc
    12301 cctctatagg tatagaagtt tatccaatgg aagtagaaga atataagtac attgtagata
    12361 aaggtgttga aggattaaca gtatatcaag aaacttatga cgaggaaata tataagagag
    12421 tacatataaa aggcccaaaa tcaaattata aatttagact agatgctcct gaaagagggg
    12481 caaaagcagg tatgaggact ttatcaatag gtgcactttt agggctaaat gattttagaa
    12541 aagaaacttt ttttacaata ttgcatggga aatacttaaa aacgaaatat cctcatattg
    12601 agctttcata ttcaacacca agaatgagac cttttaaagg gtgttttgag gaattggtag
    12661 atataagtga tactgattta gttcaagcta tggtatgtat gagattattt gaccctcatg
    12721 cagctataaa tatatccact agagaaaatt tagaaatgag aagtcatata atacctttag
    12781 gagtaactaa attgagtgca ggtgtatcta ctgatgtagg aggtcattct caagatgaac
    12841 atgatactgc tcaatttaag ataaatgatg aaagtactgt taaagatgtg gagaaaatgc
    12901 taaactcaat tggttatcag catgtgttta aagattggga aagattttaa atgtatctga
    12961 taacaaacag aaaattatgt agtgaggaac gatatttaga agttattaaa gagtctatat
    13021 tgagtggtgt agaaaatata ataataagag aaaaggattt agaatatcaa gagctaagaa
    13081 aattatatat gaaaataaaa actaaaatca attgtataga ttttcaagag caaatatcag
    13141 atgaaagttt gaaaactaat ataaatcaaa aagagtgtag aaataaattc aaggttaatt
    13201 ttataataaa tagtaacatt gaattttttg aaaaagtgga ttgtcaaggt atccatcttc
    13261 cttttaaatt atttttgaat ttaattgaaa ataagtataa ttttaatgaa aataaaatac
    13321 taggattatc tttacataaa gtagaggaag tagattattt agaaaaatta ataagaaatc
    13381 aaaatataaa aatagattac ataacattat cacatatata tgaaactaaa tgtaaagaag
    13441 gattaaatcc aaaaggaatt gagcttttaa aagaagctaa aaagattact gatattaaaa
    13501 taattgcact tgggggaatt ttaccatcta atgtcaaaga aacattaaaa tactgtgatg
    13561 attttgctat aatgtcaact ataatgaggt ctaaagatat taaaaaaacc atatcaaatt
    13621 ataatgaaaa gttgaattag taaatatagt atattgaatt tttaacttaa ataaaaataa
    13681 aaaagttatc ttttaaattt taaaaggtag cttttttatt ttatatcttt gctaataaaa
    13741 aattgtaaaa agggaaaact ttagtcagag agattaaaca atatcctaga aagatttaaa
    13801 atttagtaaa gtatggagga cattataatg actgacagta aaaagaaacg atttattata
    13861 ccacacactt ttacaataat atttttacta atagtcttaa tggcaatatt gacttggata
    13921 gtaccaagtg gtgaatttag tagagaagat gtagaaggta gaatggtagt tgtaccaggg
    13981 acttatcaaa gtgtagaaag taatcctcaa ggatttgcag atgtttttaa agcaccaata
    14041 gaaggcttta tcgattcagc tgaagttgta ggttttgttt taatagttgg aggtgctttt
    14101 ggtattgtaa ataggactgg agctatagaa gcaggaatag cttcggttat ctctaagttt
    14161 aagggaaaag aacttcttat aattccaata tcaatgattt tatttggact tggaggtaca
    14221 acatttggga tggcagaaga gacattacca ttttatatga tatttgttcc actcatgaca
    14281 tccttgggat atgattctct aacagcaata gcaattgtat ttataggagc agcagcagga
    14341 gccgccgctt caacaataaa tccattttca gttggtattg cacaggcact agctcaactt
    14401 gctcctggtt caggagtaac ttacagagta gttattttta tagcatatat actaataagt
    14461 atagcatttg ttatgtacta tgctaagaag gtaaaggaaa atcctgaaag ttcaatagta
    14521 tatgaaatag ataaaaataa taaatcaata cttaatcaaa cttcaacaga aataaaagaa
    14581 tttactttta aagaagtgtc tgttcttgct atatttggaa tagggatggc aataatgatt
    14641 tggggtgttt taagtcaagg atggtacatt ccagaaatat caatgtgttt tgctgcaata
    14701 ggtgtgcttt ctggattggt tggtagatta tctcaaattg aaatctcaga aagttttata
    14761 gatggagcaa aagatttagc atctgcagct cttgctatag ctttggctcg tggaatcgta
    14821 ataattgctc aaaatggatt tataatagat actatattaa attccgcagc agcctttcta
    14881 ggtgggcttc caaaggttat atttgtatat ttatcatttt tcttggaagc tgcattggca
    14941 tttttaattc catcatcttc aggtcttgct tcacttacag tacctgtact tgctcctctt
    15001 ggtgatttgg ttaatatatc ggctcaagtg atagtaaccg cttatcaatt tggtgtgggt
    15061 cttacaaact ttataactcc aacttcagga gtactgatgg gagcacttgc agtagctcat
    15121 attccatttt caaaatgggt aagatttata atgcctatct tgttgatttt gacagctgta
    15181 tctctagtct ttttaacaat aggtatttat atagggtttt aattaagtgt agttttattt
    15241 aagatattta gtaatggtat aaaatgataa tatgttttca ataaattgcc actaatttaa
    15301 ttagtggtaa tttgtttttt gtatttaaaa ataaatgtat ttacttgtat tttgaattaa
    15361 tatctactta gacattgttt taattgttat attttcattt aattaagcat tgatttatca
    15421 ttttttatat ttcatataac aatgcaaaaa ataattttta tatagtaaat gacaaaagtt
    15481 tacaataaat gtatattttc ttactcattc cttaaaatta ctcatttagt ttaataactc
    15541 tcatttcata tgtaaagttg gtaaaaaaat taaaattaaa agtaaaaaac taaataaatt
    15601 aatgttaatt tgaaatatat atgaaggttt ttggagaata cttacttatg ataggaaaaa
    15661 atgttaaaat aatagtgtaa tcaaatataa aggactgaaa taattaacag ttattaaata
    15721 ttaggagtgt aaaaatttat gggattaaaa gaatttgatt ttattgaaga gtctattgat
    15781 atgttgagga caatgtcacc aacattagaa actatatcag atgaaataga agagtatttt
    15841 gaaaatatct tggatgaaaa gaatcaagaa tatataaatg taacctctag aataaaatca
    15901 gaatcaagtt taagagaaaa gataattaga aatagatatt taaaaaaata tggagaagca
    15961 agtaatctta ttcataatgt ttctgactta ataggcctaa gaattgagtg tagatttatt
    16021 gaggatgaaa acaaaatata tagacttttg agaagatatt ttaataaaac agatgacaaa
    16081 ataaactatt ataataaaga gaataagaat attaaattaa aactatctga gaggcaaccc
    16141 aataagcaaa aaaatggatt tgaaatatat aaaatagatg gagtttttgc gtatttagat
    16201 agagaagtaa aatttgaact tcaaattaaa tctcttgtaa atgtgttttg gagtgaaata
    16261 gaacataaaa taatttataa aaacaataca tatttacttg ctgataaatt tataaaggat
    16321 atgatggact ctataaagaa taatcttact atgatagata atcagctttt aagtatttat
    16381 aaaaactttc attcagggaa gtcttttaat atgaaagtaa gtaaaaaaga aattgaaaaa
    16441 ttatttgcga aattagtcta tgacgctttt tctgaaaaga tgaataaaag tataggtttt
    16501 gttgtagatt ttaaaaaacc atgtgagact atattgaact attcttttaa taagcaagat
    16561 ataagtgatg aagttttagg taattttatg cttgatgagt ttgcaagatt aaatgaaatt
    16621 gtaaacaagg atatagattt taatgagcaa atagaatttg aaagagaacc aacatttgat
    16681 gataagtttt gtaaagacct aggaaatcat tttagaagta gattaaacac agaatttcca
    16741 tggaacctat tttttagaat attatttgaa atagagccat ataacaatac caaagacttt
    16801 gaaaactttg tagagtttat aaaagaaaat gtgctactag aagaaaatag ggagcaatta
    16861 ttatgccaat ttgaagaaga tagcaagctt ataattgaag atatatatga ttgtatattt
    16921 aatagtataa gtgagattga tagtgttgaa attttatata actataatct tgaaaaaata
    16981 aactttacat caagtgaaat cataaattgt atatgtagag aatatgagtg ttatggtgaa
    17041 tacttagaag aaaaagaaaa gcttatgaat acatttaaag aaaagattat tcaaatcttt
    17101 gagtaatagg tcaatgctga agtggcgcta atgcgccatt tttcaaatat atatgaatta
    17161 agtaaaatta ttttggagga ggcgatttgt atagagaaaa caggtgtaat tttggcaggg
    17221 ggaagaaatt ctagaatggg tagagataaa gcctttttag agttacatga taagcttttt
    17281 attgaaattg caatagaagc atttaaaaac tttgatgagt tgataataat atctaataat
    17341 gaagaattat attctaaata cgatattaaa gtttataatg atatagtaaa agatgttggt
    17401 ccaattggag gaatatatac tgctcttgaa tatgcaaagt atgatatagt tacaattgca
    17461 tgtgatatgc catatctaaa taatcaaata gtcgaaagaa tagctaataa aatgaatgat
    17521 aaaagtgtga tttcagtgac aaatggaaag ttacaaccat tgtgttctgg atataaaaag
    17581 agtataataa ataaagtatc tttatgtata agggaaaatg atttaaagct cagaagcttt
    17641 atagataaaa tagataaaag ttatatatac tttgatgaag aagatttatt tttaaatgta
    17701 aacactgttg atgagtatga aaaattaact aaagtttaat tagctatggt tgtaaaatag
    17761 agtaggattt atatggagga gagtttatga atttacttaa atgcgattct tgggcagtaa
    17821 tattaaataa tagcgataaa gaaagtaaag catataaaat attagatgaa cttaaaagga
    17881 atatgtacaa agttgttgct atagatgaag agaaaaaacc tattgaagga atagatgtgt
    17941 atgaatgttt aaaagatgtt ccacacaata ttgatgttgt agctattatt gataaacaat
    18001 ctaagatgga tgtgatttta gaagaagtag agcttttgga tatacaaaat atgtggtttg
    18061 aaaaaggaag ctttagtgaa atgatgatta aaaagactaa agatttaaaa ttaaatatag
    18121 aatataattt aagtt
//
LOCUS       DAEQAF010000076        17900 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.079, whole genome shotgun sequence.
ACCESSION   DAEQAF010000076 DAEQAF010000000
VERSION     DAEQAF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17900
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.079"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            256..957
                     /locus_tag="KRN00_002713"
     CDS             256..957
                     /locus_tag="KRN00_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1828571.1"
                     /translation="MNNSFLDKLIETKELKNSLYNVLKHNFLYHSNKIEGSTFTTEAL
                     ALLLDKNVVTGRHTLDDVQETVNSSYVFDTIIDSLKEKITHNFLRNLHSSLIFNTTLH
                     SRWMSGIYKTIPNMILGTDVSIAQPFEVEPKLDELIEWYYSQSEVSIKVIAEFHYRFE
                     LIHPFQDGNGRIGRFVMLKQMLENNLPIKIVSWDSEELYRNSLNSCSLGNYVPLIEYL
                     SSLEDFREVYKMLWK"
     gene            1901..2551
                     /locus_tag="KRN00_002714"
     CDS             1901..2551
                     /locus_tag="KRN00_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1828572.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            2873..4939
                     /locus_tag="KRN00_002715"
     CDS             2873..4939
                     /locus_tag="KRN00_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH1828573.1"
                     /translation="MKEVVGSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPDG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKEAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYALIDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYIYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMHEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            4956..6911
                     /locus_tag="KRN00_002716"
     CDS             4956..6911
                     /locus_tag="KRN00_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBH1828574.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKSGTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGIDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     NEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSKPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAASQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            6927..8117
                     /locus_tag="KRN00_002717"
     CDS             6927..8117
                     /locus_tag="KRN00_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBH1828575.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            9298..9672
                     /locus_tag="KRN00_002718"
     CDS             9298..9672
                     /locus_tag="KRN00_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1828576.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYEED"
     gene            9674..10531
                     /locus_tag="KRN00_002719"
     CDS             9674..10531
                     /locus_tag="KRN00_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828577.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVIKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQRIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTEYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDEIKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            10534..11172
                     /locus_tag="KRN00_002720"
     CDS             10534..11172
                     /locus_tag="KRN00_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1828578.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            12183..12917
                     /locus_tag="KRN00_002721"
     CDS             12183..12917
                     /locus_tag="KRN00_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1828579.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEISYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMHSNKQELKDAIKNISNYD
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            14452..15708
                     /locus_tag="KRN00_002722"
     CDS             14452..15708
                     /locus_tag="KRN00_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBH1828580.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFLLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASSVSKALGLEKFS
                     FALSSKVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            15771..16964
                     /locus_tag="KRN00_002723"
     CDS             15771..16964
                     /locus_tag="KRN00_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBH1828581.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIVGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGENK"
     gene            17165..17545
                     /locus_tag="KRN00_002724"
     CDS             17165..17545
                     /locus_tag="KRN00_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1828582.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKKFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
BASE COUNT         6740 a         1955 c         3034 g         6171 t
ORIGIN      
        1 agataaaaat acgttttata tgtttttaga ttaatataaa atatcacaat gaaatgttgt
       61 acaaagtgat atataataat tatatgagct ataaaattga ctaataaatt agatgaaaag
      121 ttgagactta ctgaaaataa atacaatgaa atatatacta caagtattaa attaaatctg
      181 aactttacat actattagaa taagtattat aagattataa tgatttaaaa atattaaaat
      241 aattgaggtg ataacatgaa caattccttt ttagataaat tgattgagac aaaagaactt
      301 aaaaattcac tttataatgt gttaaaacac aattttcttt atcattctaa taagatagag
      361 ggcagtactt ttactactga agcattagca cttttactcg ataagaatgt tgttacagga
      421 agacatactt tagatgatgt acaagaaact gttaattcta gttatgtatt tgatacaata
      481 attgactcac tgaaagagaa aataacacat aatttcttaa ggaatctaca ttcaagttta
      541 atcttcaata caaccctaca ttccaggtgg atgtctggta tatataaaac tatacccaat
      601 atgatactag gaactgatgt aagcatagca caaccatttg aagttgagcc aaagcttgat
      661 gaattaattg aatggtacta tagtcagagt gaagtatcta ttaaagttat agctgaattt
      721 cattatagat ttgaattgat acatccattt caagatggta atggtcgcat aggtagattt
      781 gttatgctaa aacagatgtt agaaaataat cttcctataa aaattgtatc ttgggatagt
      841 gaggaattgt atagaaactc cttaaattct tgtagtttag gtaattatgt ccctttaatt
      901 gaatatttat caagtttaga agattttaga gaagtatata aaatgttatg gaaataattg
      961 tttgcagcaa aaaaagtttt tatataaata tatttttatc tatgctattt aacgctgatt
     1021 tcttagttat tcttagcttg gactatatcc actattttaa ctatataaaa tagtggatat
     1081 agtttaacta tctctttata actattttta tgtatcttag ttgtttctta atatggggac
     1141 agttcataaa actaaaagtg atttttaatt ttatcattta taatttacca ttacatcaga
     1201 aaaatgctta tcattagaat tttcataaaa ggtacctatt tttttcaatt aactaaatca
     1261 attctattag tcttaatctt tcgtatttca aattgataat ataagaaaat aaaaaataaa
     1321 aaattttaaa ttttttattt attgcgaaaa aaataaaaag gtgctatact ttttgtaaca
     1381 tattattcaa attattaaga gatagtaaac atttatagtt taatttgtag tacactagca
     1441 tgatttgcag aacaatgaat taatctatag tataatagtt taatttaaag tacaacgatt
     1501 taatctatag tacaataact tgatttgaag tacaacgatt taatctatag tacaataact
     1561 tgatttgcaa tacaatgaat taatctatgg tataatagtt taatttgaag tacaatgaat
     1621 taatctatag tataatagtt taatttgaag tacaacgatt taatctatag tataatagtt
     1681 taatttgaag tataacgatt taatctatag tacaataact tgatttgcaa tacaatgaat
     1741 taatctatag tataagagca tgatttacag tacaataatt taaattgtag tacaaaagta
     1801 ctatcaaata agaatttcta ctttaaaaat attactaaaa gtaattaaaa tccaataatt
     1861 caatataata tggcaaaaga atagaaataa ggtgagagta gtgaaagtaa agtcaaattt
     1921 agatgaaatt ttatatcata agattattga aagtcttatt cgtggtgaat actctgtagg
     1981 tcaaaaaata ttactaaatg acctttgtga aaaatttgaa gtaagcagaa caccagttgt
     2041 acaagcagta aaaatgctaa ataaagatgg agtgcttact attatgacaa atggtaaagt
     2101 gtacgtacca gagtatgaat atgatatggt aaaacaagtt tgtgaaacga gaacactgat
     2161 tgaaacatat gctttagaaa aaatgatgca agaagaggaa gaggtttttc aacaaaagct
     2221 agatgtaata aaaagatact ctgataaatg cgaggagtac tatcgtcaag aaaaatctgt
     2281 agaacttgca ctagcagatt tggaattaca taaagccatt gtagaagggg caaataatga
     2341 gattttaaat gatgtatatg ttggtataca aggaagattt atagtagtga actatttaat
     2401 tcgaccatta aaaaatcgta attatgaagg aacagtacaa gaccattttg aaatattaaa
     2461 attcattgaa gacagagata caaaaaaagc agtagataaa ctaagaaatc atattcaagg
     2521 aactattaaa agattctgtg aagatgaata ataagttttg aagttactat atatacttat
     2581 ctattaagtt gctaaatgta gtctaagtat aatctaatta tattttaaac ataatctaaa
     2641 tataatctaa taaatataat ctaataaata taatctaata aatataatct aaatatagtg
     2701 taaataagtc taagtatgaa ttaaatatag attaagtatg aattaagcat ggattaaata
     2761 tactttaaat tacaaatatt acaaggaagc cagaaggctt cctaaaaaaa taacctttat
     2821 aaaatttttt attttaaatt taaaattttt tattttaaat ttaaaataaa aaatgaaaga
     2881 ggtggtaggg agtttgaaaa aaattactaa agaaaggata gaaaatacta tgaaaaagct
     2941 atttacgagt gaaacatttt tggaatatca atttataagt gattgccaaa tatcaccaga
     3001 tggaggatat acagcattta ttgtaaaaaa agctgatatc aaagagaatg gttacacaag
     3061 ccaagtttat atattaaaca ataaaactgg cgaattaaaa caaataacgt ctataaactc
     3121 tgttggagca tatgcctggg aagatgaaaa tactatcttg ttccctgctt tgagaaatga
     3181 aaaagtaaaa gaagctgtca aaaacggtaa gcaatgcatg agttactatg ctttatcttt
     3241 aaatggtgga gaagcagaag aactttttag actccctatc aaaggtggta aattgaaccc
     3301 tataggaaaa ggtttgtatg cacttattga ttcttatgac aatgacagac ctattgtaga
     3361 gggattgcca gaagaagaac aacagaaaaa aataaatgct tataacaaaa gacattatga
     3421 acatttcaaa gaaattcctt atgctgtcaa tggggaggga tatattagca gaaaaagaaa
     3481 acgcctatat atatacgaca gtaatataaa tgagttgaag gcaattacag cacctatgtt
     3541 taatgttgta ggtatgaaaa taagtgatgg aaaaatctta tatatagggc aagagtttaa
     3601 agatgtaaaa ggtttgaaaa atggggtcta tgtatttgat acaaacacaa acacaaatgt
     3661 ctgtatatta gaaaaagata agtatattat aaaaggtttt gaattatatc aaaatcaagt
     3721 gatactaaac ctaactgatg ctttatctta tggaaatgga gaaaatggag atttttatac
     3781 tattgatatt gatacgaaag aaatgaaact tctttcaggg catcaacatc attgtattgg
     3841 aaatacagta acatctgatg ttaaaatggg tgctggtcag acaacaaagg tagatggaga
     3901 atatatttat tacacttcta cagtagatat ggactgcatt attgaaagaa tacatattcc
     3961 aacaggaaaa caggaaaaag taacacagac aggttcagtt gattttatag atgtaaaaga
     4021 tggcaatatt gtatgtgtgg gttgtttagg aaatggatta ccagaagttt atacagtaga
     4081 gaatggaaca ttgtgtaaga aaacacattt aaatgaccat attttagagg aatataaaat
     4141 ttctgtgcca gaatacatag agtcaaaagg aagttctaaa tgggaaatac aaggatacgt
     4201 atataaacca gtagattatg aggtggggaa aaaatatcca gctgtattgg cgattcatgg
     4261 aggaccaaga ttgacatatg gaccatattt tatgcatgag atacaggtat ttacaagtgc
     4321 aggttacttt gtattcttct gtaacccaag ggggtctgaa ggtcgtggca atgcttttgc
     4381 agatattagg aaacagtttg gagatattga ttatatagat tttatggaat ttacagatac
     4441 tgtacttgaa aaatatacag acattgataa aacaaaattg gctgttgaag gtggaagtta
     4501 tggtggattt atgacgaatt ggataattgg tcatacaaac cgttttgctg ttgcttgtgc
     4561 tcagcgttct attgcaaact ggagtggcat ggagggtaca acagacattg gttattattt
     4621 ctgcaaagga caaacaggtg cttctcatat ggaaaaccac gagcttcaat ggaaacagtc
     4681 acctcttgct tatgctgata aatgtgttac accgacttta tttttacatg gtgaaaaaga
     4741 ctatagatgc tatatgcaag aagcattcca gatgttttca gcattgaaaa ttcatgggtg
     4801 tcctacaaaa ctttgtctat ttgaaggaga aaaccatgaa ctgtctcgtt ctggtagacc
     4861 aaaacaaaag ctacaaagat tagttgaaat gctagattgg ttttcggtat atataaaaaa
     4921 agataacata ggacagtaga aaggagaata taaaaatgga aaaaataaag attgaaagtt
     4981 cagatatttt tgaatatata ttccctcatg atatttcttg ttcacctgat ggaaagcata
     5041 ttgcttatat tatatcaaat atcaacgagg aaaaagactg ctatgaacat gacttatatg
     5101 tgatggacat caaaacagaa aaacaaatac atatgactca aacaaaagat gtaacatcat
     5161 ttagttggat ttctaataca gaactacttt ttacatctaa aagaaataag ccaaaatcag
     5221 gtacaacaga tttttacact atttctatag aaggaggaga agcaaaaaaa gcattttcta
     5281 ttccaaaagc ttgtagcgta cctgtatcac ttggaaataa attgtggtta ctgacaacaa
     5341 aaaatccaac ggattctaaa aaatcagaac cagatagggc agtagagggt gtagattatt
     5401 ggacatttac agataaacct tttataagag atggagaaaa tttttctcaa agaagacgtg
     5461 taacattaga attatatcaa gaaggtgaaa atataacaaa agccattaca ccaaaatttt
     5521 gtgaagtagc aggtatagac gtttcttctg ataaaaacag aattttatat actggtcaga
     5581 tttatgaaga ttgtgcaact cctttttctg gactttggga gtatcatata gacagtggtg
     5641 aaaccaaaga acttgtacca caaggaaagt accaaataag tttggcaaaa tatattggca
     5701 aagataaagt aatgttgcaa gcttcaacat tagaccgttc tatcacacag aatcatgata
     5761 tttttatact tgatttgagt actaatgaaa taaatatgat tgctagtcca gatggtatgt
     5821 atgctacatt gctggatgta gatgcagtat atggtggtgg acgtagtaat aaagttatag
     5881 gagataaatt tattggtgca agaatttgca gaactatgac agaatttaat gagtttgata
     5941 caaagacagg taatatacgt atcatcacaa aagtagatgc ttttacatct tttgatattt
     6001 acgacaacac catgtacaca gtaatgttga aagattatga gttagcagaa atatatagca
     6061 ttgatatgac tacaggtaca atgaaaaaaa tgactgcttt ttctaaacca tatttagata
     6121 ctcataaggt ttcattacct gaaaaattga cgtttgtagc aaaaaataaa gaagaagttg
     6181 atggttttgt tataccacct atagatgcta aagaaggcga aaaatatcct gctgtattgt
     6241 tcattcatgg tgggcctaaa tgggcatatg gctatatgtt tacacacttg aagcagtgtg
     6301 taacatcaaa gggaatgtat gtgatttatt gtaaccctca tggtggtgac ggttatggtg
     6361 aaaaattctt agaaatggta gaaagatggg ggtatgttga ctatgagcat cttatggaat
     6421 ttgtagatac ttgtattgaa aaatatcctg ggattgatgc agaccgctta ggggttgcag
     6481 ggggaagtta cggtggttat atgacaaact ggataattgg ccatacagac cgtttcaaag
     6541 cagcagcttc tcaaagaggt attagtaact tgattacagc ttctttaatt attgactttg
     6601 gagatagaat tatgaagcag acttgtggag ataagacgcc ttggaatcat gaggaggttc
     6661 tttggaatca ttcacctatt aaatatgtga aaaatgttaa gacaccaaca ttgttcttac
     6721 atagtgatag ggattataga tgttttatgg gggatacttt ccaaatgttt acagcattaa
     6781 aacagcttgg tgtagataca gaaatgtatt tgtttcatgg agatacacat ggattgtcta
     6841 gaaatggaag accatctaat agaattgcac gagcaaatgc tattgtagat tggtttgaaa
     6901 gatatttata ataagggggt tattctatga gtgatatgtt attatggttt agtgtcgtat
     6961 tagttttatt tgctattggg gatttaattg caagcaaaac aaaagcaaaa gtatcagctg
     7021 tatttgttac actactttta tttttgattc tatttgtcac aaaagcaata ccagctgata
     7081 ttattgaaaa agcaggtatg accgcagcag ctagttggag tgttccaatg attatgttta
     7141 gtatgggaac aatgttgaat gttaaacaat ttatagacga atggagaaca gtattgacag
     7201 catggcttgg aattgtagca gttatagtct gtgtctcatt atgtattcct ttgtttggaa
     7261 aatcaacagt attgacaagc ataccagtta taaatggagc tttacctgct actactatta
     7321 tgacacaagc agcactagaa aaaggactga cacttgcagc agctacagca acagttgtat
     7381 ttgcaattca gaagtttatt ggtacaccaa tagcttcaag agcagcgtta caagaggcaa
     7441 accgtctttt agtagaatat catgaagcaa aatcaaaagg cattgattta gcaaatgttg
     7501 atactgataa gaaagaagca gagaatacag gcacaaaagt aaaacaagct ttctgtgaaa
     7561 aatacgataa atattattct acaaatgttt gtatattttt tatagcacta ttctcttatc
     7621 tagggtatga actttcagag attattcatg taaattattc tattgtatgt cttgttgttg
     7681 gtgttattgt aacacgtatt ggtattgtac caaaagacat tttggaaaaa ggaaaaatca
     7741 agggatttat caacatggtt gtgtttgcag ctgttattcc ttctttagca aaagtttctt
     7801 tgacagattt aattagtctt tttgtaccaa ttgtgggtat gtttgcagct tctatcattg
     7861 gtatattcct tatgatgaag gtgttaccag gttggaaaat tatcggttct aaacctcttg
     7921 cttttggagt agggttttgt cagatgttgg ggttcccaac tacatattta atttcaaatg
     7981 aagtgtgtaa tgctgttgga gaaacggaag aagaaagagc atatttgatg tctaagatta
     8041 tgcctaagct ggtagttggt ggtatggctt gtatgatttc tattgtggta gctggtctta
     8101 tggtaccaat gttgtagata ggtttcatag ttaaaaaagt ggtgttaatt tataggagaa
     8161 gctaaaaagt agtattaatt tataaataaa gctagaaagt cagtattaat ttataaacga
     8221 attttatatt agttaattta ttataagaat attttctttt tagcattata atcttgattt
     8281 tatcaagaaa cagatttttt atttgctatt ctaatagtta cagtttattt ttattttcta
     8341 aaacaaaact ttaacttgat ttatctataa atagggtatt taataatatt tttggaaaat
     8401 ctttagaaag aattaaaaag aggagaaaaa atggagtgcc tcaaagtgaa cttttttagt
     8461 tcataaggca ctcttttttg tacgaaatcg aatatatttt caacgtttta aaagtgagaa
     8521 agagacttat ctctagtttg agatagccaa ttttaattat taaaattatt ttttgtttta
     8581 tttataaaag agtatccgtg ttttagaagt tagtattttt tattttatat atccaaggtt
     8641 ttctgtttct aatgttttct tttttaaaat aattagggta ttcaattata gtaaaaggtg
     8701 gattgtattt tggagtgata ttatttaaag cacagtattg aatgttgaaa tcctcatatt
     8761 ttagagtatt atcttttata atcaaaaaaa tcttctatac ttatagcaag gttacttctg
     8821 caaatattcc atacataata atatcccaat ttaaattttt ttaatataga gtttacctct
     8881 agtctacact cttgaataac tctttcctct atccaaattc ttataaattc atcccattta
     8941 ttactattta tttattacta tctaaatttt ttagtatgtt tgtaattaga aatggattta
     9001 ttcctttatg ttttttataa atagtttata acttaattta tcatcaaaca aatcattcat
     9061 acaggattac tttttctttt agatattcaa ttcttacttt taataaatat ttaatacatt
     9121 ctatcttatg tggttttaaa aagtgtttat ggctatcaac aatctctaat atttcattca
     9181 tatttatttt gtcatagtaa tattttacat cttttatatt gacaaaaaag tgctctaagt
     9241 gtatagtgtg tatataataa catcacacta aaaatgataa aaagggggtg ataaaaaatg
     9301 aaagtgctca tttctaacac atcagataag ccattatacc aacaaattaa agagcaaatt
     9361 aaagaagcaa tatttactga agaactgaaa gaaggggatg caatgccatc cataagaaat
     9421 tttgctaatg atttaaaagt tagtattttg actattagac gagtgtatga agaacttgaa
     9481 aatgaaggct ttcttacacg ccaagttgga ataggaacat ttatttcaac tggaaattta
     9541 gaaatactaa gagactcaaa gagacgtata gttgaacaaa aaatggcaga tatgattaag
     9601 gatgcaaaag cactaggaat tacacagata gagttacaag aaatgatgga tattctatat
     9661 gaggaggatt aatatggaaa atattttaga agtttataac ttaaataaga cttatactga
     9721 tttttcatta tctaatataa gctttgcatt accagaagat tgtataactg gatttatagg
     9781 tgttaatgga gcaggaaaaa caacaacaat ccgttcaata ttggatgtca taaagcgtga
     9841 tagtggaaaa ataaaaatct ttggtaaaga tttcgatgga aatgagaagg aattaaaaaa
     9901 tcgaattgga gttgtctttg atgattcata tttttatgag gagctgtcaa tggcagaaat
     9961 gaaaagtatt attgcacctt catatgataa ttggtgtgaa gaagattatc aacaaaatat
    10021 gaagcgtttt aatcttaacc caaaacaaag gattgataca ctttcaaaag gaatgaaaat
    10081 gaaatttgct ttagcattag cattatcgca taaagctgag tttttaatta tggatgagcc
    10141 tacaagtggc ttagacccac taatccgtag tcagatactt gacatactaa cagaatatat
    10201 gaagaaatgt ggtcgtggtg ttttcttttc cactcatata acatctgatt tagacaaaat
    10261 agcagatatg attgttatga ttgacaatgg acgtattata ttagagcgtg aaaaagatac
    10321 tctattggac gaacatagaa aagtaaaagg ggatattcaa tttctaaatg atgaaatcaa
    10381 aaaattattt ttaaatttag aaattacagg ttatggtttt atagggatta cctcaaaaat
    10441 taatgaagtg caaaaaaata tgccagatat tttaatagag cgtcctacaa ttgaagatat
    10501 tatgcttgca tatattgaaa ggagagagta attatgttga ttcatttagt taaaaaagat
    10561 attctgattg taaaaaaata tgtattgttg atattgttta ttgcaatagg aatcccatta
    10621 tttatattgt ggcgtttacc tccatttgca caaatattgg gatttgtact atccattata
    10681 ttttcagaat ttatgctgtg ccagtatcta ttattaaagg agagtcaata ttcaaaagca
    10741 tctgtattac tttgttcaac tccttatcct agacgtggct tagttcaatc taagtatgtt
    10801 ttatttgcaa tggtatttat ctattgtaca ttagtttact ggattgaaaa tttacttatt
    10861 ccacaaatag gaacttttga cttaacatat attttgattg ttttattaat aagttctatt
    10921 atttatggag tttatatgcc tattcaatat aaattaggat atgaaacaac aaaattcttt
    10981 ttcgtggtga taatcatggc ttcatcattt gtattaccat taactatagc tcacagcaat
    11041 tttgaaattc catttatata tcagtatcca tccatgatag tgaatattgt attgttcctt
    11101 ttaagtttaa ttatactgtt agcttcaatg tttatttcta ttaaaatttt tagtaataag
    11161 gagcttgtat aaggtaaggg ggacttttat atgccacatt taccagattg ggctgtttta
    11221 ctttgtatct tacttccaat agtatataaa gcttgtcaga tatttaaaag taaaaaatag
    11281 agtacatatt tatattgcca tttttattga gtaaagttag atggtatgaa tttaaaaggt
    11341 tacttgaaaa taaagttact tggtgtggga gagtaacatc ataatattat agattatatg
    11401 tttcttgtga atcaatttgt attttttaat agggaatatc cagtaatttt gttttccatt
    11461 gattattttt caattatgag tatgattgtg tgtattgtat accatctttt aaggtgtttt
    11521 taaaaaatta tatcgtcaaa atataaatct aaggaatcct ataaataaag cttttcaatt
    11581 ttagaaaact aataaaaagt aggaagttaa taaaaagaag ctgtctcaaa atagagataa
    11641 gcttcttttt cattgctgaa atgacgaaaa tataattgat ttaatataaa aaagagtgct
    11701 ttatgaacta tttattttga acagtagata cacttgcact caatttagtt actcctaagc
    11761 tttatgaact aaaagtttat tttgaagctt atttttatta aaagagattt tatttttcta
    11821 aataatcatc tatatacagt attgcgtttc ttttatttat tcataattta ttttcttatt
    11881 aaagtttttc tatattcata ttttccatat tactttactt ttaattttat acgaattatc
    11941 aaaaataaaa tagttattag aaaaaaataa aagtaattgc aaagcttgca attacttact
    12001 tctatattaa ttactatacc ataaaataac aaaaaaatca agtcgagtaa tccttcaact
    12061 taagtgatat actaggtatt aataattttt aattaataaa atataactag aggaaaatct
    12121 acattttctc aatttcttta attaaattga cctctaatta agtaattata aggagaaaaa
    12181 ttatgaattt agcaaaggga ttagatgttt taaaaatttc atcaaatgta ttcggtgaag
    12241 ataaagttat gtatattcct gtaatctaca cagaagatga tgcaacactt attgacacag
    12301 gtcttccggg tcaaggtgat ttaataattg atgctcttaa taaaagtaac acgagctttg
    12361 ataggttaaa aaatataata attactcatc atgatataga ccatatagga aacataaatt
    12421 atctaagaga aaaatctaag aataatatca aagtatatgc atacaaaagt gaaatcagct
    12481 atataacagg agaagaaact ccttttaaac tttatatgtt ggaacaaatg gtagataaaa
    12541 ttgatgataa gatgcttagt atgctaaatg ttatgggact tggatttaaa tcatcatata
    12601 ctaaagtaga tgtgtcatta gataaccatg aaaaattgaa tctaggtgag gaaatagaag
    12661 ttatacatac aggaggtcac actagaggtc acatatgtct ttatttaaaa gagtctaaag
    12721 tacttattgc tggagatttg ttacaggtag aaaatggaga acttaagcct gttgatgtaa
    12781 tgcacagcaa caaacaagag ttaaaagatg ctattaaaaa tataagtaat tatgatatag
    12841 aaacgatagt ttttagtcat ggtggattat atcaaagaaa cataattgga acattgaaaa
    12901 acctaattat tgagtagtac tatatgattt acaataattt cttaaattac ttaaaattat
    12961 atctaaagat gtagaatcaa aattaaatat aagtaataag aattttgctt taaaattata
    13021 cttaagtgtt aagggtgata cgtagtatta caagtatttt agaatataat tttttatagt
    13081 aattttaaag ttctacaata cttcagttga aaaatattta acagcatagt ataataggaa
    13141 agaaaatatt ttaaataaac tttagtatac aaagtgaaga aaaatattta aattatatat
    13201 aatattgtag agtgatgtaa aatatttaag ttatatatca taatacagag tgaagaaaaa
    13261 tatttagata atgtaccata atacaaggtg agtaaaaata tttaaatcat gtatcataat
    13321 gcaaagcgaa gaaaaatatt taaataatgt accataatgc agagtgagta aaaatattta
    13381 aataatgtgt tataatacaa agcgaataag attatttaaa gcatgtgtta taatacaaag
    13441 cgaataagat tatttaaagc atgtattata atataaagtg agtaaaaata tttaaatcat
    13501 gtatcataat acaaagtaaa gaagattatt taaaccatat atcataatgc aaagtgaaga
    13561 aaaatgttta aattatgtat cataatataa gcagagtgaa gaaaaaaatt taaataatat
    13621 atcataatgt agagtgagta aaaatattta aatcatgtat cataatgcaa agtgaagaaa
    13681 aatgtttaaa ttatgtatta taatataagc agagtgaaga aaaaatttaa atcatgcatc
    13741 ataatataag cagagtgaag aaaaaaattt aaataatata tcataatgta gagtgaagaa
    13801 aaaatttaaa tcatgtatca taatataagc agagtgaaga aaaaatttaa ataatatatc
    13861 ataatgtaga gtgaagaaaa atgtttaaat tatgtatcat aatataagca gagtaagtaa
    13921 aaatatttaa atcatgtatc ataatgcaaa gtaaagaaaa tcatttaaat tatatatcat
    13981 aaaaataata tgaaatattg aacactaata atattagagg ctttactatt ttaattgata
    14041 ggttatatta tttataacat taaaaataca atttacataa aatagacata tgaaaaataa
    14101 aaaattatat aataattatg ggaatgaggt tctcccttgg atgataatat cctaaactgc
    14161 caatgagctg atgacttcta tgatatcata gatgccacca gctttttttg ttgtttaaat
    14221 cgataaaatg gaggtgaatt acttactaaa tttttatttt ttaaatttga agaaatattt
    14281 aattaataga aaaaatagta gattatatgt taattatttt attaagaatg ggttaagagt
    14341 gtacctatat cctatcaatt taaaaaacaa ttatgatagt cattacattg actacagttg
    14401 atgcaataaa actttcaaaa aatcttatga tgcaaatgga aaggaattaa aatgatagaa
    14461 aaatttaaaa ctttaatatg gattaaaatg ataataagaa ttaaaagcgt ttataaaaca
    14521 tatggtggac tatttttgtt aggactcata ggtataccag ttggtgcaat tataggtctt
    14581 atagacacca tatttggaac ggttcttcta aaagttacag atattcgaga aacatatcca
    14641 atgtatctga taccattttt agcagtagta ggagttgtta ttgcttattg ctattttaaa
    14701 tttggaggaa aaagtagtaa aggaatgaac ctaatatttg aggtagggca tggagaagaa
    14761 gaaattattc ctttaagatt ggttccattt ataatatcag gtacatggtt aacccattta
    14821 tttggtggta gtgcaggacg agaaggagtt gctgttcaga ttggtgcaac tttttcacat
    14881 tgggtaggta aaaggttgcc tataaaaaat gcttctagta tttttctagt aactggtatg
    14941 gcagctggtt ttgcaggatt atttgagaca ccaatagcag caatactatt tgctatggag
    15001 gttttggtag ctggttcact ggagtatcaa tcgctttttc ctgcgtttac tgcttctttt
    15061 acagcaagtt cagtatcaaa agctttaggg ttagagaaat tttcttttgc actttcttct
    15121 aaagttgtat ttgacttgtc aatattttgg aagcttattg ttttaggaat tatttttgga
    15181 atggttggtg gagcatttgc atggtgtttg aaattgtcaa aaagaaaaat aggtaataga
    15241 ttaaaaaatc ctatgataag gattgctatt attggagtat gtcttagtgt attattcctt
    15301 ttattttata aaggaagata ttcaggttta gggacaaatt taattcaaaa tagtttctat
    15361 ggtggagaaa tttattcatt tgactggctg ttaaagttta tacttacaat actgactttg
    15421 tcagcaggtt ttcaaggagg agaggttaca cctttgtttt ccattggagc tagtcttggt
    15481 gtattgttag caggattttt taatttgcca attgaattag ttgcagcgct tggctatgct
    15541 agtgtctttg gtagtgctac aaatactttt tttgcacctg tatttatagg ggcagaagtt
    15601 tttgggtaca gttatttacc ttatttcttt gtagtatgcg ctatttcata tatatttaat
    15661 atggataaat ctatttattc actacaaaaa atttcaacaa aacaataaat aaaacaacat
    15721 aatgtatgat tagaagagaa agaatattag agaaaggata gggtaggaat atgttgacaa
    15781 gtttagcttt gattttttta ttaggaatgg cctcgggagg tatttttaag aggataaagt
    15841 tacctaactt attgggaatg ttacttacag gaattatatt aggtccatat gttttaaatt
    15901 tgattgataa ttcaatacta gatatttctt ctgaccttag aaagattgca ttgattatta
    15961 tattaacaag ggctggatta tctttagata taaacgattt gaagaaagtg ggaagacctg
    16021 ctgtacttat gtgctttatt ccagctactt ttgaaattat cggaatgata gttttagcac
    16081 caaagttact aggcgtttct atattggaag cagcagtcat gggtgcagta gtaggagcag
    16141 tttctcctgc aattattgta cctaaaatgc ttaaattaat ggaagaaggt tatggtacag
    16201 aaaaaagtat tccacagatg cttttagcag gaacttctat agacgatatt ttcgtaattg
    16261 tgatgtttac agtattcaca ggattggcac aaggaaatag tatatcagct attagttttt
    16321 tacaaattcc agtatcaatt atattaggtg taatagttgg agcagtgatt ggaatctgtt
    16381 tagcagtatt ttttaagaag gttcatatga gagattctgc taaaggggtg ttgcttttaa
    16441 gtatctcatt tttaatgata agtttagaga ctgctttaga gggtattgtg ccattttctg
    16501 gattattagc agttatgagt attgggattt tccttcagat aaaatatcgt gtagttgcaa
    16561 gaagattgtc cataaagtat tcaaaactat gggttggcgc tgaaattctc ttgtttgttt
    16621 tggtaggggc aacagtagat ataagttatg catttaaagc aggaattgga gctgtaattt
    16681 taatatttgg agttctttta ttccgtatgg taggagtatt cttctgcctt attaagacaa
    16741 atttgacaat aaaggaaagg ttgttctgta tgattggcta tattccaaag gctacagtac
    16801 aggcagcaat aggaggtgta ccacttgcaa tggggatggc atctggacaa cttattttga
    16861 cgttagcagt tctagctata cttataactg cacctcttgg agcttttgga attgatgtaa
    16921 cttataaaaa attattaact tctgtaaaag gcgagaataa gtaaaaataa agattatttt
    16981 aactggtaag ttatattttg gaaaaggatt atactattga atacaatata aaaaaatcat
    17041 ttgggagatt aagaaggtag aagttaagaa cagattttaa ggtgtgttat gattattaga
    17101 attgattttg tgaaattatt attgtaatat ttaattatat agataaagaa gcggagtgat
    17161 aactatgtgt ttaaaaaaat tatcaaaatt agagttagtt attatgaaat ttatttggaa
    17221 tttagatata aaaaccaatt catatgagat tattgattat atgaaagaag aacataattt
    17281 accagaaaaa gtagctttaa aaactttatc aaaactatca aagaaaaaat tcttatatgt
    17341 tcaagaaaca ggcaagtgta tgtattatac agttgcaata aaagaaaagg catatttaga
    17401 gtttatatca agaaatgtgc aaaatctttt gaagaataat tttataagga atttattagt
    17461 atcatttcac gaagaggagc taacagagga aaagataaag tcgttagaaa actgggtagt
    17521 aaattgggaa gaagcttatg tataaatgtt attattttta ttacaattta gataattttg
    17581 gttttgtaag ctctgcaact atttttagat ggttgcagag tttattttta ttttttattc
    17641 ccttaagcaa tacttaaaag taaacgcatt tatatttact aacttcaatt acttctaata
    17701 cttaaattac tttttaaaat gatatgtcat atctatagta atctagaact tgtttctatt
    17761 ctttatataa agtttttatg aatgatatat ataatattcg ttcatttgat taaaaataac
    17821 aaaatattaa ataattctac tctgatagtt tgttaaaaaa ataataaaaa atattaataa
    17881 acaaaaaaaa aattatctta
//
LOCUS       DAEQAF010000077        17806 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.080, whole genome shotgun sequence.
ACCESSION   DAEQAF010000077 DAEQAF010000000
VERSION     DAEQAF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17806
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.080"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(193..1407)
                     /gene="dpaL"
                     /locus_tag="KRN00_002725"
     CDS             complement(193..1407)
                     /gene="dpaL"
                     /locus_tag="KRN00_002725"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBH1828583.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKLLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLNTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            complement(2012..2551)
                     /locus_tag="KRN00_002726"
     CDS             complement(2012..2551)
                     /locus_tag="KRN00_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
                     /protein_id="HBH1828584.1"
                     /translation="MQYAIELYYDKKTEKQLFDLSKKIADEKISTKYLEWKTRPHLTL
                     ACFNDVDEACCIDKLKGFAQNHKVIPAYIGSVGMFNDTKTVFVSPIMNSSMYQFQREL
                     YEVLQDFDSNGWEWYHPNRWVPHCTIALTGDDESEAFFRASDVLLREFKKISGEFVSI
                     GLVKITFPVEEIFTVNMNR"
     gene            complement(2628..4433)
                     /locus_tag="KRN00_002727"
     CDS             complement(2628..4433)
                     /locus_tag="KRN00_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1828585.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLSKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            complement(4829..5206)
                     /locus_tag="KRN00_002728"
     CDS             complement(4829..5206)
                     /locus_tag="KRN00_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBH1828586.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            6111..6596
                     /locus_tag="KRN00_002729"
     CDS             6111..6596
                     /locus_tag="KRN00_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828587.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            complement(6796..7335)
                     /locus_tag="KRN00_002730"
     CDS             complement(6796..7335)
                     /locus_tag="KRN00_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1828588.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFTQGALESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(7328..7741)
                     /locus_tag="KRN00_002731"
     CDS             complement(7328..7741)
                     /locus_tag="KRN00_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1828589.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            complement(7777..8898)
                     /locus_tag="KRN00_002732"
     CDS             complement(7777..8898)
                     /locus_tag="KRN00_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1828590.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNIEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILIPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            9497..11149
                     /locus_tag="KRN00_002733"
     CDS             9497..11149
                     /locus_tag="KRN00_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBH1828591.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTNQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            11448..12197
                     /locus_tag="KRN00_002734"
     CDS             11448..12197
                     /locus_tag="KRN00_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828592.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYVASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            12210..14237
                     /locus_tag="KRN00_002735"
     CDS             12210..14237
                     /locus_tag="KRN00_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828593.1"
                     /translation="MNIFYTAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAVSNGKFFYKTPLVKLIRYEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQNSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYDNIQIKKIIKKQVLAFFNIPFLLGILDCIFAT
                     LVYKTALMQNLLGNSFSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKN"
     gene            14381..15964
                     /locus_tag="KRN00_002736"
     CDS             14381..15964
                     /locus_tag="KRN00_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1828594.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNISDNGVANTSFKTPLDITKITFDTTKHKGIISIKEQVENLGGTISVSDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            15936..16556
                     /locus_tag="KRN00_002737"
     CDS             15936..16556
                     /locus_tag="KRN00_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828595.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYKEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGGTCFPSENTEVIIEDLTTMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(16751..17677)
                     /locus_tag="KRN00_002738"
     CDS             complement(16751..17677)
                     /locus_tag="KRN00_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH1828596.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNSDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNTHSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTENSTYKNPESIHEII
                     IRKLNSESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
BASE COUNT         6150 a         2762 c         2168 g         6726 t
ORIGIN      
        1 agtttttatt ttgaattttt catttgcttt acttttttat ttgctttact ttttcattta
       61 tttagatttt tcatttgctt tactttttca tttgttttag tttttatttt atttaaagtt
      121 ttcacttatt taagttttta ttttccttaa atttttcatt tatttgttaa gattttcttt
      181 tccttaagtc ttttatttac tttggcattc accattccaa actatatctc tatatttatc
      241 agggtcagta tctccttctg tacttattaa taatacttta gagttctcat ctagtttcaa
      301 agcttctctt aagtctttta aatcttcact ttcaaggatt gaaactaatg ctccagttgt
      361 aactgctcca gattctccag agattacttt ctcatctcct cttagagggt ttcctaatat
      421 tctcatacct ttagcagata cccagtctgg tgctgaaacg aatgctgatg aataattttt
      481 taacacttca aaacctatag tgtttggttc tccacaagca agccctgcca ttatagttgg
      541 catatctcct ccaacaaatc ttggttttcc atctccagct tctgctgatt tatagtaaca
      601 atcagcctca tcagcctcta ctactactgt tattgggcat tcatcatata ttgaagcaac
      661 atatccttga actgcaccag caagtgaacc aactcctgct tgaacaaata cgtgtgttgg
      721 tctatctact ccatattctt ttaattgttc tatagcttct ttagccatag ttccatatcc
      781 ttgcattatc catgctggta tttcttcata tccgtcccat gctgtatctt gaaccattac
      841 tccatggtca tcagcttctg cataatcatt agctaatctt actgcatcat catagtttaa
      901 gtctgttata ctagcatctg caccttctcc tttgatttta tttaatctaa attcagaaga
      961 accttttggc attaatacaa cagatttttg acctaattta ttagctgtcc aagcaactcc
     1021 tctaccatga tttccatctg tggctgtaaa gaaagttatt tctcctaatt tttcttttat
     1081 ttcttttgaa gttaatttat cataccctaa ctcagatata tctgtattta atctttgagc
     1141 taagtatcta cccatagagt aagaaccacc taaaacttta aatgcgttta agccaaatct
     1201 ataagattca tctttaacat atattccgct tacgcctagt aattttgcta agttatctaa
     1261 tttaactaaa ggagtctttt catattgtgg aaagctttca tgaaaagctt tagcctttgc
     1321 aatctcttca tcttttaaaa attcaattcc tttttctttt tcctctgatt taggtaagtt
     1381 atttaatttc cattttattt ctctcattta ttttatattc ccctttcaaa tttttcggtg
     1441 tcattttaat tttttatctt tgtgccttat agcaaagcaa ttaccgtgcc aatattattt
     1501 attctaaaaa caattttttt atgttggaat tacatacttt tataaaattt ctttaaagtt
     1561 tataaatttt gagtgtgaaa aataagattt ataaaagaaa aaattctcat attgggaaat
     1621 ttttatcaat acgagaatta tcaattcgag aaatcgttta tttgtcttaa ttcttccttt
     1681 attatgctct tattttttat atgtctattg ttttgtcaga tatattacta cttttatttt
     1741 ctataaatat atggctataa ccttcttacg cataaactct ataaatttat atactttata
     1801 ttctttgtta cccaaagcct ccaaaatagc ttaaatcttt tcatagcttc ttacagaagt
     1861 ttacatggtc gtccccccaa taagcaaaag tgcaatatgt gtaccattgt gccctacttg
     1921 cgactattga gctgtcgaaa ttcgcaactt cgcatttatc tgatgaaatg cactatacaa
     1981 aatattcata acatccacaa cagagttaaa gttacctatt catattcact gtaaaaattt
     2041 cttccacagg aaatgtaatt ttaaccaatc ctattgagac aaactcacca cttatttttt
     2101 tgaactcacg cagtaataca tcacttgccc gaaaaaaagc ctcactttca tcatctccag
     2161 taagtgctat tgtgcaatgg ggtacccaac gattggggtg gtaccattcc caaccatttg
     2221 aatcaaaatc ttgtagtacc tcatataatt ctctctgaaa ctgatacata ctgctattca
     2281 ttataggtga tacaaacacc gttttagtat cattaaacat gcctactgaa ccaatgtaag
     2341 caggtattac cttatggttt tgtgcaaacc cctttagctt gtctatgcaa caagcctcat
     2401 ccacatcatt gaaacaagcc aaagtaagat gaggtcttgt tttccattct aagtacttcg
     2461 tactaatttt ttcatcagcg atttttttag ataaatcaaa aagttgcttt tccgtttttt
     2521 tatcataata cagctctatc gcatattgca taataacacc tccaccataa agtaaaaata
     2581 cctatctata aaaacacaca aatacctatc attttaatat tatattacta ctgttcctct
     2641 tccaattttc tatatagtgt agccaaacct atacctaagt cttttgctat cttcttcttc
     2701 gtctttgtat ctcttccata cttattcaac aacttgttta tgtaagtcaa ctctaattct
     2761 ttaattgaaa gtatcctttc ttgattctct actatccctc caactatatc atcttcaaat
     2821 attatattta catccttatt tttataaata tttccattaa tattataata gtttaaaata
     2881 tctaatggaa gcatatcttt atatattatt ccatcatctc caaccaaatt catcatatat
     2941 tcaactgcat tttccagttc ccttatattt cccggccaat tatagttaat caacatattc
     3001 attacatttt cttctatttt acttaactga atacctaatt ctaaagaata tttagaagca
     3061 aacttcatca ttattgcctc aatatcatcc tttctttccc taagaggtgg caaatttata
     3121 ggaattacat tcaatctata gtataaatca tccctaaact taccttcatt tactaatttc
     3181 aataagtttt tatttgtagc agcaatcact cttatatcta aatctataag tttatttgac
     3241 ccaattctcg caaattttct ctcttgtaaa actctaagta actttgcttg taaaggcatt
     3301 gacaaatctc ctatttcatc aagaaatata acaccttcat ttgcaagttc aaatttacct
     3361 actttacctc cactactagc tccactaaat gcacctttta tatagccaaa tagctcactt
     3421 tcaaggagat tttctggaat agcagcacag tttatcgcaa taaatggctt gttccatctg
     3481 ctaccttcag catgtatagc cctagcaatt agctctttac ccgtaccact ttccccagtt
     3541 ataagtacag ttgaatttga ctttgctaat ttcttagttc tctcttttac ttttaacatt
     3601 gcttctgaat ttccaattat agactctata tcactatttc cccagccact attcactttt
     3661 ccatgtcctt tatgattgat atatgtcttg tcaaatatta ttattttgtc gtattgattt
     3721 atatatggat ataccggaat tattttggca tttatattat aaattttgtt atcaatatca
     3781 atttctagta attcatgtcc atttgaggaa gattcaacag atactatatt tactatattt
     3841 tctattatat ttttatctat atctaatttt tttagagcta tattgtttat ataagatatt
     3901 ttgctattta tgtctagtat tataacgcct ttttcaacat tttcaatgat ttctatcatc
     3961 atatccattt ttctactgct attttttgac gcttcatgtt cttctatttt catagaaatt
     4021 aaatcgcata tatgattgac aaattttaaa taattatcta tttttgcact tatttctact
     4081 tttttagttt tatctgtgct aatagcacca attactccta tagttcgatt attatacttt
     4141 attggaactg ctattattac tttatttagg catttcatgt aatgggaaca ttctatacaa
     4201 agctgattat cacatatatc caatacgact aattcctgac ctgtctgtat aacattgtca
     4261 taaataaagc cctcagtaac aacgctttca tttatctttg atttatacag acctgtacca
     4321 ctaattctta ttaatctatc gtcaactatt tcaatatcta catctaacac actagctact
     4381 gtttcagtgt attttatcat ttcttgttga aattctttta atttacttaa catagtttcc
     4441 cccattagaa tttaatttac caaattatca gtttagctat attttaacat atagtcactc
     4501 tttaaaatat atataaaaca ttacttattt atatatttgc gttaaaacag acaatattaa
     4561 tttataaaaa gtttgtttta tatagtaacc ttaattataa tatgcagaca ataaaataaa
     4621 tcacaataca ataataaaaa aaagctttcc tcatataaca aatatatttt tgacataaaa
     4681 atatacatta tatgagaaaa gctcaatagt taaatattta gatagatttt tatatagact
     4741 tttttaatat aaactttttt aattgtagac tttttttatt agtttttaat ttttattagt
     4801 tttgttattg gttttattgt tataatactt ataatactgc cattgcttca atttctaaaa
     4861 ctgcatcttt tggtaattga gcaacttgta cacatgacct tgctggtgga ttttctttaa
     4921 aatatgtagc atatacttca ttaatatcat taaaatcctt taaatctttt acgaatactg
     4981 tagtcttaaa tattttatcc atacttgtac cagcttgttc taatattgct tttacattat
     5041 ctaaagaagc ttttgttgct tcttttgggt cagatactaa ctcgccagtc ttcatatcta
     5101 ttggaagttg acctgatgta gaaactatgt ttccaacttg aattgcttga gaatatggtc
     5161 caattgctcc tggagctttc tctgtagcta ttactacttt tgacatgact tcacctccta
     5221 ttattaagtt atatttacag gaaaataaaa tttcctaaac accaatatta atacgaacct
     5281 ttagattaaa tttcaaatct aaaacttcaa ataatcaata cttagatgat tatgtttatt
     5341 tgtgtcttgt taacttttat taaagcaatt aacgtgccaa actttattta tatataaaat
     5401 tttgtgaagt cattcaaaat agttacttct gaattttttc gtaaaaaaac gctctaaaat
     5461 tactttttta tgatgtcaat ttttttctca tatctagaaa tttaccaaca tgagaattct
     5521 tgttttgaga atttacagat taaagttatt ttttaacctt aaattctgaa cctcccatga
     5581 ctaaagtcac agggttcctg cttcatagaa ttttgcataa tcaagttatt acatatgaaa
     5641 gaactatagt tgacaatccc actattataa ataataaaac ctttacccat accttattta
     5701 ccctagttat catagagcct attgaaaata taacagctaa atataataat aaccaaaaaa
     5761 ttatcaatat ctaccactgt tgctgaaaat ccaaaaaact accttttgat agtattactt
     5821 aacaatctaa ttaatctcat aataaattta caacttataa ataaattgtt atattggccg
     5881 tatctcaaca actttctcct ttcctagttt taaatctttt atagaattgt accacgtcta
     5941 agtaaatttt catactatta agtcttattt ctaataaatc attagctctc attctatgcc
     6001 caataatgta agattgcagt aattttattg attttaatag ttttatttaa tatacttata
     6061 ttaattattt tcatatgaaa ttattattta tataggggga tttttttaat atgagcaaaa
     6121 gtgaattaac agcagaaaca acagaagaaa tgttagaagt actaagtggt aaagattatg
     6181 atattgcatg tcatttacat gaacttggta aatcattaga ttgtaaaatt gaaccaaaaa
     6241 caggtgctcg ttcttacaaa atagtatatt caactaagaa accaaaacgt agcttattta
     6301 ctattgaatg taatgaaaaa aaatggagag ttaaagcaaa tctttttcat ctaaatacat
     6361 ataaagatgc tgtggaggaa tgctctaaaa ctattaaaga tagtataact aaaactcgta
     6421 cttgtaagaa atgtaattca aagtgtattg gaggttcttc gtttgaatta gatggaaagt
     6481 cttacctgac ttgcatagga agtggtcatt attttgcaaa tatggaagaa atggattgga
     6541 aaaacctaga aaaattaatt actaaagaaa ataatattat gcaggaatct gtatagtttt
     6601 ttaagggtaa ttattaaaat atatgagcaa caacagatac ttaaataggc ataaaaaaat
     6661 aaagggtata ataaggatat agaataaaaa taaatgatat agcacaaaga ggctgtctca
     6721 aaatacagat aagcctcttt ttattgttga aatgataaga atatattcaa ttttatacaa
     6781 ttttatacaa acatactacg ccaacttacc catttcatat gcctgtttca ttgccttact
     6841 tcccttaata tcacctacat tccaagcacc tacaccatat actatacctt tttccttaga
     6901 gccatttaga catgatgtaa atcctctaaa tccttctatt gttctttcca tatcagccac
     6961 attttcatct gctgctgtaa cgataaaata gaaatcttta tcacaaattt cagtatatct
     7021 agagcaagtt ctatcaatca tagttttcat ttgtgcattc atagtataaa aataaactgg
     7081 agtcgctaaa acaatcacat ctgccccaat cattttttca agaatttctc ccatgtcatc
     7141 tgtctgtgaa caatttgctt ctttttcata acaagcacca catccagtac aatagttaat
     7201 atctttatct tttaaaaata tcttctcaac ttgattttta gattctaatg ccccttgtgt
     7261 aaactggtca cacaataaat cagaatttcc accttttcta ggactagctg atactattaa
     7321 tacattttta ctcataagat actgcctcca ttttcttatt tctactgctc tttaatactt
     7381 tttctttctc aataatacct tcttcatatc tatcaatctt aaaatttaat cgttccaaag
     7441 ttttttgcat ttcttctatt ctttttgcta gttggtttct ctgctctatt aaaagttctt
     7501 ttctagcttt gatagtactg ctcccttgtt gaaacatagc tacatactca attaatgtct
     7561 caatagaaag acctgcacct ctcatacact ttatgaaatt aacccactca caatcttctt
     7621 ctgtaaaaga cctaattcca cttttatttc tatttacagg tggtattaaa ccaattcgtt
     7681 cataatatcg taaagtatcc gctgaaagct cgtatttttt actaacttct gaaatcgtca
     7741 tacatatctt ctcctcttga tattgtatag attgaattat ttctcaaagg tttctgctac
     7801 attctttaaa gcatctataa ttttaatgtg ttgaggacag ctttcttcac attgtttaca
     7861 ttcaatacaa tctgaggcct ttccataagt tttagtataa ttattatagt agaccatctg
     7921 tgttgaaaat ccagtattaa gagcttgttt ttctgcattg tacaacgcaa aatagtttgg
     7981 aatagcgata ttttttggac agccttctac acaatactga caggcagtac aaggaattaa
     8041 aattgattcg ttgataatct ctactgcttc atctataata ttatattcct cttgtacgaa
     8101 tggtttgaaa ttttgcatat atcctgtatt gtctaataat tgttctatat ttgacatccc
     8161 acttaagacc atcataacat tatctttact tgctgcaaaa cgtattgccc aagatgaaat
     8221 tgacatatct ggattgtagt cattcaataa tttctctgct ttttctggta tctttgcaag
     8281 tgtacctcct tttactggct ccataacaat tacaggctta ttatgcttct ctgccacctc
     8341 gtagcatttt ctagattgta tgctttcatt atcccaatct aaataattaa tctgtaattg
     8401 cacgaagtct acttctggat gctcactcaa gactttatcc aataattctg cactatcatg
     8461 aaaagaaaaa ccaatattct ttatttttcc ttcttttttc ttttcttcaa taaacttaaa
     8521 gctatcaaat tttttagcta cttcataatg tgacacgcct atattgtgta aaagatagta
     8581 gtcaaaatag tctacaccac atttttctaa ttgctcatta aaaatggttt cttgctcttc
     8641 tttcttcttt aaagccatta atggaagttt tgtagctata gtaaaactct ctcttttgtg
     8701 tctttttact agagattctc taagtgctat ctcacttttt cccatgtgat acacataggc
     8761 cgtatcaaaa tatgtaaatc ccctttctaa aaaagtgtct accattttat ttaaatgttc
     8821 catatcaata gttgtaacat cattttcatc ttttattggt aaacgcatta atccaaatcc
     8881 taattttttt gcctccattg ttttacttcc ccctttaaaa cttgtttgtt ttttctctct
     8941 actttaacta ttcttacaag tatataattc ttgtataatt atactttact acttggagtt
     9001 aacttcaagt caatagattt ttttattttt aagacaaata ttataaaaat acagttcttt
     9061 aatattaatc cattacatgt ttctttcacc ctccaattct caaacttcac aaactccaac
     9121 atgtaaagaa atatatacct taagaaattc agtccattaa tattactaca aatacttttt
     9181 agatatgttt aaaaagaaat ttcacctaaa atatttataa aagatttaga aataggtctt
     9241 gtgtctattt taaaatatat aaaagagtgg taaagactta tttataagat aaaaaatgaa
     9301 tagtgtatac cctttttaaa aagttttttc ctttttatat ttgtgataca atgttaaata
     9361 taaaaaggaa aattttgtat taaagaaatc ttatttgttg attttgtaac ttcaaactca
     9421 gcatcaattt gattttaaga ttatatttta ttaagtatgc taaataacaa atttttaaag
     9481 attgtgaggt aaaaatatga ataagaaaaa tttagctata ttaatatcag gtatgatgtt
     9541 tttttctagt tcttcagcaa tttttgcaga caatactaca aatcaagaaa gattaatagg
     9601 taaaacaaga tatgaaacag cagtagaagt aagtaaattg ggatgggttc aatcaaaaac
     9661 agccattata gttaatggta attctattca aagtgcgctt tgtgcaaatc catttgctaa
     9721 gctaaagaat gcacctatac ttttagtaaa caacaacagt attgaaaatt caactaaggc
     9781 tgagcttaaa aggcttggtg tagataatgt gtacattgta gatagtggaa atagcatttc
     9841 ttctaaagta gaaaatgaaa taaaatcact taacataaaa ataaataaaa tagtaggaaa
     9901 caatatatat gaaatgtcta caaatgtact taaagaaata gataagataa aaaaggtaga
     9961 aaatgttgca gttgtaaatg gactaaaggg actatctgat gcagttagta tagcttctcc
    10021 agcagcaata cataatatgc ctataatatt agtatcagat gaaaacagca atgatagtag
    10081 tataaatttc ttaaacaata ggtctataaa aaaatcttac atagttggag gaaataagat
    10141 tttatcagac aatacagtaa agaaatatcc aaacagagaa agaatcagtg gttcagatag
    10201 aaacaatact aatgcaaaaa ttattgataa attttataaa gataaaaaaa taaataatgt
    10261 atttgtagct aaagatggta ttaaccaaga aaatgcatta gtagattcat tatcaatagg
    10321 agtactagct gctaaagaaa attctcctat aatgatatct aatggtagcc ttgtaaatag
    10381 tcaaaaagaa tttattaaaa ataaagatat agatgaaata acacaagtag gaggaggata
    10441 taatcaaaaa gcatttgaag atattttaaa actaaaaaat gtgaacataa gaaataaaac
    10501 taaaaaaata tctttaatac aggctaaaga aatattaaaa caagctcttc caggaagcaa
    10561 tattttagtt tgttattatg atgaagatga taatgaatat gactgcaaag ttataaagga
    10621 taatatccta tatgagatag aaattgatgc ctactctggt aaaataatag aaattgaaaa
    10681 agatgatgac ttaaatgata ataatttagg tacacaaaat atatcattgg ataaagctaa
    10741 gtctatagca ttagatgcca ttcctaatgg taatttaatc tattgtaaat atgatgctga
    10801 agataacgaa tacgaggcta aagtaataaa aaataagaaa acatatgaat tagagataag
    10861 tgcatttgat ggaagaattg tagatattga catggacaat gattctgatg atgactttga
    10921 tgataatgat aagaataact ctaatactaa tgacaacagt tctattatta gtgctgaaaa
    10981 agctaaatca ataatgctag ataaagtgcc tggtgggaaa atagtaaaat ttaaatatga
    11041 tgaagatgac aaagaatatg aaggtgaaat aataaaagga aaaactgaat atgagataac
    11101 aattaatgca attactggta aaatattaga atttgaaata gatgattaat aaaaaatata
    11161 tattctatta attattacaa gcaataaagc cataaatatt gaaattttca atatttatgg
    11221 ctttatttta ttttttttaa tttaaatcca cattatgcca ttatatatat ctatgcactc
    11281 ttttaaatta aaatcttgtc catcatccca aacctaataa agttagattt taaacaatat
    11341 attgtgatat aagtaatttg tgtagaatta ttgcgtgatt tactcatgaa gaaacaataa
    11401 ggttaatata taatttgact atattaagac gaaaggagac atatacaatg aatacaatat
    11461 taaaagtaaa taacataact aaaacttata ataaagggca acagccgagt ttagataagg
    11521 tatcctttaa tgtatcagaa ggtgaattta taggtataat gggagcttct ggctctggga
    11581 aaacaactct acttaatgta ttatctacaa ttgataaacc aacaagtgga gatattttca
    11641 taaataatat aaatttgaaa tcgcttaatg acacttgtgc tgctgatttt cgtaaggata
    11701 atttaggctt tatctttcaa gagtattttt tactagatag tcttacaatt ttcgagaata
    11761 tttcagtacc tcttacactt cagaaactca atccagataa aatagaaaac atggtaaaga
    11821 gtctagctga acgatttggc atagcttctc aattaaataa atacccaaat gaattatctg
    11881 gtgggcaaag acagagagct tcagcagtta gagcaatagt aaaacatcct agtattctct
    11941 ttgcagatga accaacagga gctttggatt ctaattcagc tactgaacta ctccactcac
    12001 tacaggaagc aaatgaggag ttgaaaacaa caattttaat ggtaacacat gatgcctatg
    12061 tagcaagttt tgcaaataga attttgattt ttaaagatgg tcatatcatt aaagaattaa
    12121 ataaacaaca gaataataga catacatttt atgagttgat tattcaagaa attgcaaaat
    12181 tggatactaa aagataggag gataatttaa tgaacatttt ttatacggca ataaagaatc
    12241 ttaaaaaaaa cttttcattc tattctctat atctactttc agtctctttt gttattactg
    12301 tatttttcgc atttacttca ttttctgtta ataagataat gctagaaaaa atttcaactg
    12361 atggtagagt tgaatctatg tgtaatgtta tttcgatatt tttgatggca tttgtcatct
    12421 tctatatggc atactcaaat cgattcttct tgagacgtcg tacaaaagaa ttaggtatat
    12481 atgctttact tggctatcgt aagtttacaa tattatcgct acttaccttt gaaaatgtat
    12541 taatttgtag tggagctttt attattggat tggtattagg agcattggca cataagggta
    12601 ttgtctttgg aattacagca ctacttaatt tatcaattga taattcacag ataccatttt
    12661 ttaatataaa tgcaataaat aaaacaatta tctttatagc attagttgtt ttagtcttag
    12721 ctgtatcaaa tggtaaattt ttttataaga ctccacttgt aaaattgata agatatgaaa
    12781 aaagtgcaga aaaaaaatta aagttcagaa aaattccagc ctttatgggg tttattatga
    12841 ttttaagcgg gtattgttta tcactagata ttcttcgtgg agctaaatca gtatgggtaa
    12901 gtattggatt ttatcaaatg ggcttgataa ctatgattat cattgtaatt ggtacagttc
    12961 tctttatcaa ttcctttctt ccatatatta tgcaaaatag taaaaaaaat aaacgtactt
    13021 tctacacaga tatgaagata atagctattc caaactttat ctatcgtata cgttcaaact
    13081 ctaaaactct aattatgctt acattactct ctgctactac tttgacagtt tcaagtgtta
    13141 tggcactgtc cttatactac cctattgcat ctgtttcgcg tattgcacct tcagagatag
    13201 aatttagagt agaaaaaaat aaacaaatag aagatgtaaa acaaattgtc agtcaatata
    13261 cgtctaatac agatgatatt atttttacac agacaaatat ttataaggta aaatcttcat
    13321 caaaagacct tccatttgaa tatgaaattg gtacatctaa gaataattta tccaatagta
    13381 gttcttctaa agaagttatt tcaagagaat caggatttga atgtatatct ttttctgatt
    13441 attatacttt attaaaggca caaaatcgaa caaagctact aaaacaactt acccctttaa
    13501 gggataatga atgtatttta atgaaatatc aaccaaataa tgatggatat agtgaaaatg
    13561 gaacgattta tccattactt gttaatggta aagaaacacc tgtagctgta agggaaacat
    13621 cattaaacaa tgctatttct tttgccaata gcgttggaac acttatcgtt aatgatagta
    13681 tatatgagca aatagcacaa aataaattac caatgacaag cattttaagt attaatggta
    13741 aatcaattaa aaataatgaa aatttatata gtaatatttc agattattta gatggaagcc
    13801 cttatttaca aggatattct cacaggataa atgatttgtt atcaattaat agttctacat
    13861 ttctgttaat cggatttctt gtggtattat tctttattgc tgttggaagt attttatact
    13921 ttaacaatat atcagcaatt tcagattcaa catctgatta taagatttta cagaaaatgg
    13981 gttatgataa tatacaaatt aaaaaaatta ttaaaaaaca agtattggca ttttttaata
    14041 ttccgttttt acttggtata ttggactgta tatttgctac cttggtttat aagactgctt
    14101 tgatgcagaa tttacttgga aattcatttt cacaatacat acctgtgatt attgcaattt
    14161 tcttaacttc tgtagtgtat ttgatatatt atatacttac tattaaatcc tgttgtaaaa
    14221 ttgtattaaa aaattaatat ttaccaaatc gtcaagctta gaggtgtgac gatttggtat
    14281 acttcattta taagtatttg atataattta aaattataga ttcttaggtt tgatttagtc
    14341 ataaaattaa tataattaac tcataaggag gtgtataaga ttgacaaatt ttaatttaaa
    14401 aatactattt ttaggaaact acattctatc acttctcttc atgggaatat ctacaagcac
    14461 tgaaacttat atgaatatcc aaagcattat tcccttaata atttcaacat tattactcat
    14521 agacatcaca tatataacct cttgtaatgt ccgagaaaat aacattattt cattgttttg
    14581 tggattacta gcactagaca gttggtattt actcttatca tttgtaacca caccaatagg
    14641 cactattatt tttaaaatat taagcacagt tatagtgtat gtctctatta aatttatatt
    14701 tttatttttg tttcaaggta gtggatacaa tttccgtaag ataacagaca ttttattgct
    14761 tatcacctgc attggtgcaa ttgtaggagc atttatttct aacagaacgt atgcttgtat
    14821 gtacggaata cagtttgttg ttagtataat aagctttttc tatattattt tttatcattt
    14881 gaaaagggtt gtttttgtca taaaaagcga aaaaaaacct atatcgattt cagtatttat
    14941 aacaattata ggattcctta cttattattt ttttacacta agaatatcaa atcatattgg
    15001 taattttgga atctatctaa ctgtactggt attttttatg agtattcatg gtattgcact
    15061 taaagaaaat gatagttttc ctatttcaac agtttttaac ataaaacaaa gggctatatt
    15121 tctttttata agtattttag taattagctt ggtcgtacta tttgccaatg ggaatttttc
    15181 tataatatta atagctataa atgttttatt tatgctcatt ttcctctgta acattatttt
    15241 ggagtttaac cttagagatg aaaaaaataa agtagttaaa aatagcaagt atacttttgc
    15301 attagaaaaa ttacaacaag aagaacaact aaaaacagag ttttctaatt ttttacatga
    15361 tgacatatta cagaacctgc tttcaataaa aaacatgatg agtaagtcat atcgcccaga
    15421 tgttcaagat attatatatg aaacacttaa caatctaaat acatgtataa ggaagcaaat
    15481 gcaagactat catcctgtta ttttaaaaaa tttaacagta aaagaaaatt atcagaattt
    15541 aattgaaagt gtttcttcat cctttccaca aaaaaatatt tgtgtttcat ttaagtgttc
    15601 tgatacttta ttcttagttg aaccatatga tatattgata tatcgactga ttaaagaatt
    15661 attgacaaat gtgtataaac attcaaatgg tagccatgca tggatagctt tagcactaga
    15721 aaaaaatata ataaaattaa atattagtga taatggtgtg gcaaatacat cttttaaaac
    15781 gcctttagat ataactaaaa ttacttttga tacaacaaaa cacaaaggga ttatatcaat
    15841 taaagaacaa gtagaaaatc taggaggaac gataagtgtt tctgataata tacctcatgg
    15901 agtttgtgta cagattacaa tccctatgaa aggagatggt tcttataaat attttgttag
    15961 ttgatgacca tatgcttttt gctaaaagct tgtcaattgc actagaagaa tacaaagaaa
    16021 tcgaacagtt ttattccaca caggacatcc ataatctttc agaaatgatt caagataaaa
    16081 aaatagacat tgtcttaatg gatataaacc ttagaggctt aagtgaatgt gatggcttaa
    16141 aagtagctta taatttatta gagactaatt caactattaa aataataatc ttgactggat
    16201 acgacctccc agtttataaa catgaggcta aaaaaatagg tatctatgga ttcctaaata
    16261 agaatattag ccctgatagt ttaattgatt cattattaaa agtctatcaa gggggaactt
    16321 gttttccatc tgaaaatact gaagtaatta ttgaagattt aactactatg gagaaaagaa
    16381 ttttacagct tatctgtagt ggtaaaaaaa gaaaaataat tgctgatgaa ttgtatataa
    16441 gtgaaagaac attatcaaat catttacaac acatatatga caagctagat gtttcatcat
    16501 cagttgaggc tattacaaaa gctattaaaa tgggttatat ttctccagta tattaaaaaa
    16561 agtgagtgtc tcaaaataaa tcttctaact cataaagcac tctcctttgt attaaatcaa
    16621 atatattttc atcatttaaa caattaagaa gaggcttctc tctattttga gacaactcca
    16681 ttttaataca ctatttatac ataaacatat tttaaacaac taaaaagcaa ctaatatctt
    16741 aataaatatc tcaatacata tcttcataac acatatcacc ataattacaa gcagataaag
    16801 aactctcctc atttaaatac gactcaaatt catacccaaa cagaattgtt ggttctatat
    16861 atatttccat atctgtatat ctccatcttc ttacctttgc ctctataacc ttgtaaaaat
    16921 cttctaaact atacccttct tttaatcttt tatctataag tgccttagtt atactcaaat
    16981 cagctttaaa attttttcct gattcactat ttaattttct tataataatt tcatgtatgc
    17041 tttctggatt tttataagta gaattttcag tcaaatcttc atccgaattt tcaaaggtat
    17101 ttttatttaa attcttttta tttaaattat tttttaataa ttcttttttc tttgtctcat
    17161 tttctgtttc atacccagta tgaattatca aatcataatc tttgtctata ctctcttgat
    17221 ttatacggct gtgtgtgttg gtattactgt tcttaaacaa ctcatctcta tgtttatatt
    17281 tcattgtttt ttggttattg ttaatagttg catcaatgta tttctctata tttttgaaaa
    17341 tatcactatt ctttgttaca atttctgcat tactactttc agaacaaaca taactatata
    17401 cagaacaaca atttcccttt actcccctac ttattaatct caatatacct aaatctataa
    17461 attcatttac aagtctactt attgtagata tagatacatc aaggtcagat gcagctttcc
    17521 ttactgtcat cataaattgt cctcttggca gagttccttt taatctttgt atattttctt
    17581 ttctcattac atagtgatta aaccttattc tatttacatc tcttttttca ttaaaatata
    17641 atactgctga atttaattga taaaaactat tactcatatt cccactcctc caatttaaat
    17701 agataatttg ttgtaaagtt tttagatttt taaataactt attaaatgat tatttttatt
    17761 aaaaagtatt ctttgatatt ttcattttaa agttttaagt ataata
//
LOCUS       DAEQAF010000078        17702 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.081, whole genome shotgun sequence.
ACCESSION   DAEQAF010000078 DAEQAF010000000
VERSION     DAEQAF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.081"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            780..1532
                     /locus_tag="KRN00_002739"
     CDS             780..1532
                     /locus_tag="KRN00_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828597.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            1522..3633
                     /locus_tag="KRN00_002740"
     CDS             1522..3633
                     /locus_tag="KRN00_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828598.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCAVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISIVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SIFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNDEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLSNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFKKIIGIL"
     gene            4017..4727
                     /locus_tag="KRN00_002741"
     CDS             4017..4727
                     /locus_tag="KRN00_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828599.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYTKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
     gene            4864..6201
                     /locus_tag="KRN00_002742"
     CDS             4864..6201
                     /locus_tag="KRN00_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1828600.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPVNILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENSVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNSI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTENEFSLFLYIRLF"
     gene            complement(6537..7106)
                     /locus_tag="KRN00_002743"
     CDS             complement(6537..7106)
                     /locus_tag="KRN00_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH1828601.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(7458..8471)
                     /locus_tag="KRN00_002744"
     CDS             complement(7458..8471)
                     /locus_tag="KRN00_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1828602.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKTFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQINVY
                     IDN"
     gene            complement(9083..10657)
                     /locus_tag="KRN00_002745"
     CDS             complement(9083..10657)
                     /locus_tag="KRN00_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBH1828603.1"
                     /translation="MKKDTSHIIKRAEHFQVILIGEGLMVGAVAGLIVLLYRILLGQA
                     GTWLSQILKFVEGSTIKIIAWFAVLAVLAWIVSKLVDWEPMISGSGIPQLEGEMTGKI
                     KQVWWRVLPTKFIGGFLSLMGGLALGREGPSIQLGAMAGKGISRALDRGKTEEKFLLT
                     CGASAGLSAAFHAPLAGVMFSLEEVHKNFSVSVLISVMTASLTADYISANFLGMESVF
                     QFDIGNVLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTFGKLLIPFI
                     MAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGSGAPGGIFF
                     PLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTGIILIFEMT
                     GSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKERGEKILDQFSV
                     MFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMTDERDSGAV
                     YDKMENLCKEHTAHIF"
     gene            complement(10817..11353)
                     /locus_tag="KRN00_002746"
     CDS             complement(10817..11353)
                     /locus_tag="KRN00_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBH1828604.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSISAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(11426..11839)
                     /locus_tag="KRN00_002747"
     CDS             complement(11426..11839)
                     /locus_tag="KRN00_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1828605.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            12305..12985
                     /locus_tag="KRN00_002748"
     CDS             12305..12985
                     /locus_tag="KRN00_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBH1828606.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEGTI
                     SDMQSNINGIEGTISDMQSNINGIEGTISSMQGNINGIENTISGMQGTIGDMQGSISG
                     MNGTISDMQGSISSMDGTINSMQDSITDMQVEIKEINSRLDNMEPDIKDLKTGQVETS
                     SRLDTIQSDVTEIKSDVKINRNTLDTVIKHTSSLVKDTSDIKNDLNNIEIVTSKNSND
                     IAKLKSVK"
     gene            complement(13584..13772)
                     /locus_tag="KRN00_002749"
     CDS             complement(13584..13772)
                     /locus_tag="KRN00_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1828607.1"
                     /translation="MLQKGKQGADKKYLDNMFFVKGYVEELLFLDKSYDIVFSCIVFH
                     HCTNVQNIFCIFWKWQEC"
     gene            complement(13998..14531)
                     /locus_tag="KRN00_002750"
     CDS             complement(13998..14531)
                     /locus_tag="KRN00_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH1828608.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            14848..15198
                     /locus_tag="KRN00_002751"
     CDS             14848..15198
                     /locus_tag="KRN00_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828609.1"
                     /translation="MGKVRIGCKKEKYFYVRNPVKSLVDRITENEQFAIYHFTHKYNW
                     RNKVFSILQRLIRLEKSKNELYIYEALVSVSFLWLIMITNIVFPPIKHKNIINIHMQK
                     ILRYIEKYYCFTLY"
     gene            15167..15486
                     /locus_tag="KRN00_002752"
                     /pseudo
     CDS             15167..15486
                     /locus_tag="KRN00_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(16317..16889)
                     /locus_tag="KRN00_002753"
     CDS             complement(16317..16889)
                     /locus_tag="KRN00_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1828610.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(16951..17214)
                     /locus_tag="KRN00_002754"
     CDS             complement(16951..17214)
                     /locus_tag="KRN00_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH1828611.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(17214..17435)
                     /locus_tag="KRN00_002755"
     CDS             complement(17214..17435)
                     /locus_tag="KRN00_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH1828612.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
BASE COUNT         6458 a         2810 c         2047 g         6387 t
ORIGIN      
        1 catttctatt atattgcaat ctcttattta ttacagttct ttattatact acagactttt
       61 attattacag catttctatt acattgtaaa gtcttattta ttacagttct ttattatact
      121 acagaccttt attattacaa cactttatta ttttaacttc tttactataa tatagtaata
      181 ttttaatatc tcaaaatcat atcaatcact tttcagcata gtctaaaata cttccacttt
      241 ctaaaattat ctatcatacc tatactaaca atacttttta acccttttat tatacatttc
      301 aattgttttt aacaacctat ttatttccaa aactccaata tattttctca attacattgt
      361 gttaataacc cctaaatcct ttcaaattat ttacaataca ttccattaaa taatcttact
      421 gctctataat tctttttttc tttttaaccc tactatacat tatttacatc atttttttca
      481 atacaacatt cgttattcta taaccttttt acttttacta tatacctttt ttctaactac
      541 accttcaatg ttccacatca tattacttta ccacaacaat taatacctaa aaataaccct
      601 ctaaatcctc caataatata atcaatttaa ctataataat aacctctcac actatccaaa
      661 caatatattt tcaaacatta caaaaaaaca tccaactatt acaatatatc tcatatccct
      721 cctccccttt caaatgctat cattgactta caagataaat gaaagtgagg atgatatata
      781 tgcttaaagt aaaccaatta tgtaaatcat ataaaacagg cagtaaaaca tatcctgtat
      841 taaaaaatat ttcttttgaa atcaacaaag gagaatttgt cgcaatcatg ggttcatcag
      901 gaagtggaaa aactactctt ttaaattgta tttcatgttt tatcccaatt gataatgggg
      961 aaataattct tggcaataat aatataagaa atttaaaaga aaaggaactt tcagaagtta
     1021 gaaaccaaca actaggattt gtattccaag atttcatgct atttgatggt cttagtgtat
     1081 ttgaaaatat atgtgttcca caaattatca aaggtagtca agtcttacaa atggaaaacc
     1141 gtgcaattaa tctatgtgag ctatttggta ttgaacatat cagaaaaaaa taccctgccg
     1201 aaatatctgg tggagaaaaa cagcgtacag cagtagcaag agcactcatg aacaacccag
     1261 atttaatatt agcagatgaa ccaactggta accttgatag taagtcttgt cgtacagtca
     1321 ttgaatcatt tttaaaagca aagcaagaat tagatgctac tatactcatg gttacacacg
     1381 atagctttgc agcaagcttc tgtgaccgag ttattgtgct taaagatgga ataatttata
     1441 aagaagttgt aaaatcaaat tcaagacata aattcctaga tgaattacta gaagttttaa
     1501 aagaaatggg aggcgctcaa gatgacaatt aataaattat acagtaaact tcgagcctat
     1561 aattggaaga actatacaac tttattcttt tgtataatac tttctgtggt attagtaact
     1621 tcatatgctc taatttattt tagcccaaca atacaaaaca tacttccaac tggtggagat
     1681 agcagaaaac aggctacaat gatattctca gttgctatat taggatgcgc tgtctttact
     1741 acatacgctt cttccctctt tttaaaattt aaaagcaagg aaattggtat tttcatggct
     1801 ctaggaacag ataagaagaa attaaaaaaa cttctatttt cagagatatt gttaatttca
     1861 atagtatgct gttttttagg tcttatatta agtattcctg tatcttttgg tatatggaaa
     1921 atatttcaat tagtgattat tgataccaga gaaatgacat atcattttgg aactcaagga
     1981 ttcatatatg gatttatatt tagtatattt gtgacattat gcatatttat actttctgta
     2041 aaatttatta atcgtacaaa tataattgat atattaaatg accagagaat atctgaacca
     2101 atacaggatg taaaggactg gtatggtata ttaggtataa tttttattat actcggtatt
     2161 tttctaggat atctcgtacc ttcactaact ataaacaaat taaattataa actaccatct
     2221 atatggagct ttacttatct actctctctt attggaatat atatgattat gacatacata
     2281 gttgtacatg ctaaaagagg aaaacatcca gagaaatact ataaaaacat catatcaact
     2341 agcatgatga gatttatggg aagacaaaca gtaaaaaaca tgtgtgttat ttcatttttg
     2401 attgcaggag cattatttgc tgtattctat gttcctaata tggttacagg tatctatgat
     2461 actcttaaaa ataaccctat agattatact tttacctaca atcaaagaga taaacaggta
     2521 tcaaaaaaag atattgaaca attagcagat aaacacaata taaaaattca aaactatatg
     2581 gaaattcctt ctatagaatt aattgttgat ggtgtagaat caatatatca taaagatgga
     2641 actatcgaaa aggtatatat gaaaaaaagc tcctatgata tgttctttaa ttccaaagat
     2701 ttttccaagc taattggcaa accaataact ataaaaaatg gtgaatatct tgctgttgta
     2761 aataaaggaa atgaaaatca agattataaa tataccaaat ttatatcaag cccagtcaca
     2821 gaaaaagaaa tcccctttag atatgctgga aaaataatat ttaatggttc tttttttcaa
     2881 aatagaagta tgaacgccta tgtccttaat gatgaggatt ataaatcatt tactaaagat
     2941 ttatccataa aaaattacaa taattctata ctatttaatg tagataaaga tacctatgct
     3001 tttgccaatg acttaaagaa agaaattata aaaagaacat ctaaggaaat gggcatgttc
     3061 agtggttatg atgaatacgt aaaaaaacgt tatgaatcaa ctggaagaaa atattttatg
     3121 gatgaagaat atccaagtgg tgaaggtcat ttaaaactag acccaaacaa caatcagttg
     3181 tatcttaatt ggaaatacta tcctaacttt aaaattttac aaagccaaga tatgataaaa
     3241 aacatggcag tcttcttaat gttattcata tatgtggcaa tcatatgttt tacagcagta
     3301 ggaatcattg catatacaag gggtgttact atagctataa atcacaagca ggtctttatg
     3361 gatttaaatc gattaggagc aaacaatgat tatataaagt tctgtattag aaatcaatta
     3421 aagaaagtat tttcataccc tcttattgca ggaagttttt taatttatct gtttaatttt
     3481 atgattatgt taagtaatga tggtagaatc gtcaatagtg aggtcaatgc tcttttgata
     3541 aacttaggtt ttatagggat ttgtggggtt tatatgtacc ttatatatct attaacttac
     3601 aagaaattca aaaaaattat tggtatttta taataaggaa ggttgttaga tttttaaagt
     3661 aataaaatca ttggtgtttt ataataaaaa aggttattag gtttttaaag taataaaatc
     3721 attggtgttt tataataaaa aaggttatta gatttttaaa gtaataaaat cattactttt
     3781 tataataata aaagcatttg tattttataa taagaaagat tgttagattt tttaataaga
     3841 aaatcattag cacttcagaa taagtttaat agaatagttt taagtgtaag tatactaata
     3901 taaaaaattt tattttgcta tctggatata attgttattt cattttatat atctaggtag
     3961 caaaatatat tatatactta actatataaa tataaaattt gaaaggaggt aaaaaattga
     4021 cttcgatttg tatttgtgat gatgaaaaac aacaaagaaa catgctgaat aaaatcatta
     4081 caagagaaat ggatttgtgg ggctacccct accaaataaa agaatattca aatggagaaa
     4141 gtctagtata caatctagaa cacgaaaatt attacataga tattattttt ttagatattg
     4201 aacttggaaa aagtaatggc gttgacatag caaaaactat acgaaaacat tcaaaagata
     4261 ctataatcat ctttgtcaca ggtttttctg actatgtatt tcatggatat gatgtaggag
     4321 ctttgaacta catcttaaaa ccttataaaa ctgaaaaaat atgtaaagta ttaaaagaag
     4381 cactaaaaaa attagaacaa tggaaagaaa actttattac agttcagatt ggaactaatc
     4441 tttgtaaaat taatacaaaa gatatcctct actttaaaag tgagctaaga aaattaactg
     4501 tagttacctt tgataaaaca ttagaatact acggaaaatt aaatgatatg gaaactgttc
     4561 ttccctctaa ttttatacgt acacatcaaa ggtatattgt caatctaaac catgtagata
     4621 gtataactca aacttataca aaagttcaga atgaaaaaat tcctataagc cgtaaaaaat
     4681 atcaagaggt tgtaggaaaa tttacaaggt atatgttaga atcttaattt ttgaagttca
     4741 atctctagaa ttttattttt caaaatcaat tctttgaaat ctaatttcca gaattttaat
     4801 ttttaagatt taatttttta aaacttagtt tccagaatct taattaatag aaaggtatat
     4861 taaatgggca cttattcttt aatctctaca agcataaatt ttattctaat attaatcaat
     4921 attttcatag ccttttttct ttataagttg acttcctatt ttatagactt taggaatcat
     4981 tggattttca aaatcatatt gattttgggc tactctatta ttagtcaaat gataatatgg
     5041 ctttccgacc ccgtaaatat tttgtttaca ctattcggat attttatact acttataata
     5101 tgtagcaaaa gcaaattaat tcctataata tcagttgtca tgatacttta tcctattata
     5161 attgggctta attttctttt tataaacaac cctatatatg aggaacttat acactcaaaa
     5221 gagtatattt taatactttc aatagtccag ataatttctg ctctaattaa attattattt
     5281 tggtttttaa tacatatttt cctaaagaat agattggtca atataaaaca atacttatca
     5341 aataaaatat ggatttttat tgatatggta tgtatatctt catttttatc aatattaatt
     5401 gctattattc tgccacctac taatttaatc cctatgggta gtaataagaa tattatctta
     5461 ggcaacttac cttatggcac ttatctaatc atcttgtcag caattctggc aaatatcggt
     5521 gtgatacttc ttttacagcc attgattgaa aatgtaaaga tgaagataga aaaacaagca
     5581 aatcacctaa aagaaaaata ctataactta ctagaaaatc aacaaattca aatacgcaaa
     5641 atgcgacatg atatgaataa tcactttcaa atgattgaat cgtatttaga aattgaagat
     5701 attgctggag ctaaaaagta ttttaatcag ttaaaaatag gtataggtac tcttagtgga
     5761 aaacaatttt gcaaaaacca agctcttaac tcaattttaa atcttcgtca tacaagtttg
     5821 gaagaaaata gtgttgatgt gcactttaat atagatatag acaatcactt gggtatagaa
     5881 cctatagatt tatgtactat tttttcaaat tctttagata acgctataga agcatctttg
     5941 aaaattcctg atttgtcaaa tagaaaagtg gtattaaagg cacgttgtga gaaggagtat
     6001 tttagctatt tattgacaaa caacaaagta aattctatca atagaaaaca agaactattt
     6061 atttcagata aaaaagatag taattctcac ggatatggta ttgagaatat tagagaaatt
     6121 gttaataagt acaatggaaa attggatatc tcttatactg agaatgaatt ttctttattt
     6181 ctttatatta gattatttta gtctaaaatt agattatctt atataataca aattagattg
     6241 tttgatacta tgtaaaatta taataactta taattaaata tttacacata tattcattaa
     6301 cttaaaattt aatcaaatgt gatattttat ttaccttagt aaaaatgtgt gtgtctcaaa
     6361 ataaactttt tagttgatga ggcactcttt tttacatgaa atcaaatata tttttatcat
     6421 ttcaataatg aaaaagggat ttatctctcc attttaaaac aacccctttt tctattaatt
     6481 actttcttaa aaaatataat acgatatata agataaatat ctaattgtac ctatttctaa
     6541 ttatatctat tagaatacaa cacctttgcc ttttcagtaa actccctaac aaaatctagt
     6601 ttactatctg tataagcatc acgattatgc tcatacttct tccaaaggtc caacttaagt
     6661 ttttcatact cctttgcaac atctgggtgg tcaattaagt aatctctaaa aaacaactca
     6721 tcattatcac ctacatacct tatatgcaaa tgaaaaactc gttcttcaaa cccatctact
     6781 gtataccctt tattaagtga aagcctacta ctgctctcag acatacaaat atatccattc
     6841 gactcaatca aatctttaat atctttcata ttataatcag gaattatctc aatcagtatg
     6901 tcaacaatgg gcttggcata aatcgtactc acagaagtac ttccaatatg acttattcta
     6961 acaatttttt gcattggcaa tattccagtt agtctatatt gttcttcttt aaaccaattt
     7021 ttccaacatt ctttgtgagt agtcaaaaat ataggaaaca agttccataa ctcctctaaa
     7081 gtcatatctt ccaacttctt tttcattagt tacctccttt taaatttgta ctttatattt
     7141 tttctttttc aaatttactt agttaatatt taactttatt ttttatcaaa tcacttttct
     7201 aattatgtaa atttttctaa atttagtttt taatgtatta taatagattt ttacccttct
     7261 tacacttttg catttcttta aatattagaa catttttaat ctacaattgt agtaattttt
     7321 tctttacctg tatttactgg cattggagct tctaaagaat aattcattgg ctttaatata
     7381 attaaagtaa atttaacata tgtgaaagat acttattaaa attatttata ttaatttctt
     7441 gttaaacttt gtatttttta attatctata taaacattaa tctgatatgt aggttttgaa
     7501 ttagttctgt tttcaatagg tgtttgtttt gaaagtggat aaaatattga tttagtagta
     7561 attaaatcaa ttttaaaata tgtaatagaa gataataaac ataaaataac tgctatcaaa
     7621 ataccatttc tgtacttttc attaaacata ctaaacactc tttttttaat atctgactcc
     7681 ttatgtaatc cagccacaaa tttatttgaa ctatttgaac cttttctcat tgcactaatt
     7741 attgtcaatg cataatcctg cttctcttct atcgtacaat tcttcaaaac tctttcatca
     7801 caataaaatt cacaatccaa atctataaac ttctccatta tatacacaaa aggattaaac
     7861 caataaacac attttaaaaa tatcaccaaa tacttaatat aaaggtcttt actcttaaaa
     7921 tgcatcaact catgcctaaa tatccagttt aactctttca atgtataatc acatggtggt
     7981 aaaatgacac acgaattaaa aaatactgga ctttcaactt catatgaata tttaagccgt
     8041 atttttttat ttatcttaag ctcttttaat aaattttcat aaagattttt tatcttatca
     8101 tcctcaacat cataagacaa atcatttatc atatttttaa gcttaatata tttcaataaa
     8161 gtataaacta aataaaatat cgtaatagca atccaaacag agactaaaac agtactatat
     8221 acaatagaaa tactattaaa attgcctaaa cttatcttat taatattacc attatatttt
     8281 gactcattaa atataaaagt ataattcata aatggtaatg atagcttaat aatcacaata
     8341 agccatatat agtaattaaa ttttttactg aaagtcttaa ataaagttat tctaaagact
     8401 aataaaataa ctataaaaat acaacttact aaaattgttc taaagatatc atttaaaaat
     8461 gaactaacca cagatactca cctttcttat acttttatat ttatataatc atctacacga
     8521 atactaaact gatatgtagg tttttaatta actttgtttt caataggcga ttgtcttgaa
     8581 agtgttttaa aagttgatat aacaatgatt taggagtaat aaggtcaatt ttaaaatatg
     8641 taataaaata taataagcat gaaacaacta ctatcaagat accatttcca aactctataa
     8701 gcaaaatggg ctaatacaac cttaacccct tttaattatt ttcatttata aataaattct
     8761 attcttccca aaatatcgta attaaaatat attaattaaa atatcccaat aagaatatct
     8821 gaaaaatctt ctacctattt tttcaaaccc tttattccca ttcctcatac aatagtacaa
     8881 cttttagcac agtataaata taccattagt ccatataatc tcattaacaa atatatacaa
     8941 ttattttctt caaactcttt tacatctaag atatcacatt ttcattttct tatattaatt
     9001 ccttaactct ctttcaaatt accaattttt taatcaaatc ttcattaaat attctatcat
     9061 tattaaacat tcatcattat ccctaaaaaa tatgtgctgt atgttcttta cacaaatttt
     9121 ccatcttatc atacacagca ccactatctc tctcatctgt catagtcaca attacatcac
     9181 ttggtctaag aattgtctta cctctaggaa taatttcttc tccacctctt tgaattgcta
     9241 ccaaaagaca attttcaggc cactgtacat cctgaattgc cttgttcgca acaggagagc
     9301 caaacataac agagaactgg tctagtatct tttcgcccct ctctttatgt acaggttctc
     9361 catttttttc aagtaacctc tcaagaagac tttcataaat aggtttagac ttcataagtg
     9421 tagccacaat atatgccaca attgaaatta ctgatagtga aagcatttga ctaacagaac
     9481 ctgtcatttc aaaaattaat atgataccag tcaaaggggc acgcacaata gctgtaaaat
     9541 atcctgccat agccaaaagc acaaagttat ttacataatc gggattcatt ccaaaaactt
     9601 taacacctac cataccaaat attccaccta taaatgctcc taaaacaagc aatggaaaaa
     9661 atattccccc tggcgcacct gacccaaaac taacagccga aaatataaaa cgtataacaa
     9721 aaatcaaaac aaccattcca aaaatatatt catgacttgt aagttcttca actaaattgt
     9781 gtccactccc cagaacatca ggcataacaa gcccaagaat accagccatt ataaatggaa
     9841 tcaacagttt tccaaacgta ccaattttag gaatcttctt gtataaagac tgcacatata
     9901 gagtaaacca gttgtaaaat gcccccataa ctccaagaat aacacctaaa atcactatta
     9961 atccataata atcttgtggc aacacatttc caatatcaaa ctggaataca gactccattc
    10021 ctaggaaatt ggctgaaata tagtctgctg tcaaagatgc tgtcatcaca gaaattaaaa
    10081 cagatactga aaagttttta tggacttctt caagtgaaaa cataacaccc gctagtggtg
    10141 catgaaaggc tgctgataat ccagcacttg ccccacaggt taacaggaat ttttcctctg
    10201 tcttccctcg gtcaagagct ctagaaatac ctttacctgc catagcacca agctgaatgg
    10261 aaggaccttc ccttcccaaa gcaagaccac ccatgagtga taagaatcct ccaataaatt
    10321 ttgttggcaa cactcgccac catacttgtt ttattttccc tgtcatttcc ccctcaagct
    10381 gagggatacc acttccagaa atcattggct cccagtccac caactttgat acaatccacg
    10441 caagtactgc aagtactgca aaccaagcta ttatttttat tgtagaacct tctacaaatt
    10501 ttaaaatttg gctaagccaa gtaccagcct gccctaaaag tatcctgtat aaaagcacaa
    10561 tcaaaccagc cacagcccca accataagtc cttcaccaat caaaattacc tgaaagtgct
    10621 ctgcccgttt gataatatga gatgtatcct ttttcatact attcctcctt catccaataa
    10681 ttctacacaa tctgaatctc caatgactaa agtcatgagt gtgtacagat attttttaat
    10741 caacaaaaat agatttttac ttactaaata taagaaaata attgctcaat ttctcaataa
    10801 atgtgaattt attcttttag gtatttattc tccacagtcg tgcttcttcc agcaaaatat
    10861 ttattaattc ttgctttctc tgtgtataga ttttacgatt gtcctcaaac tgtaatgcta
    10921 atttttgttt atgactatca tagagttttg ctttgtctgt aaaagtattt agataatctc
    10981 gaaaattgat ataattattc catgcaacac tattccattc aacaacatga atatggtgag
    11041 tacgagtatt tttctcaaaa tctcccatag caaaaagtaa ttgttttggt acatcctgac
    11101 ctcgaaaaac gattccacat tgctctaacc tttcgaggta taatttagct tcctctaaag
    11161 aagcaacacc tacaacaata tcaataatag gctttgcgct aatactggga atagaagtgc
    11221 ttccaatgtg ttgaatatca atagcagtct tatcccatat actttttaat aatataatga
    11281 catcttttgc acttttatcc catatcatct gatgttccaa taatttaacc ataccacatt
    11341 ttaaacctat cactatatac cacctcaata taatccacct ttatatatat tacaattttt
    11401 tctatcttga taaacagtga tttagctatt tcactttttc ttgacactcg ctacattccc
    11461 tatcatgaat agatataatt cctccacatt tagaacaagt atatctctcc ttctgctttt
    11521 gcataaactt ctctaaaccg tactgctgaa caaatttact attttccata aggcttgctt
    11581 gatatctctt gttataactt ttttcaagat tttttatgag tttacaagga aaattgaaac
    11641 attcaaaaca ataaaacaat cctttttgac agacacaatc ctttattttg cacttacggc
    11701 agtgttctgg ctttcctgta tcgccgttca aacaaccagc acatggcttt ttgtgataac
    11761 aatgcttata gcaaaccata caattcattc cacaaggagc aaacataatc gtatcaatac
    11821 tctcttttgg cattttcata acattttact cctttcaaaa atccaatttg tcgaattgtt
    11881 atatattcat attgtaacat aaaaaatagc taaaaaattc atgcactttc attgccaata
    11941 aattttcaag gaaatatgaa agtttaaaac taagaataaa aagagataaa aaggaagcta
    12001 ctaatcaaaa tattcaaata caagtaatca atataaataa cttaaggtat atttaaaagt
    12061 atatgatatt accagcagtt ttaaatacaa atataaccac acatgcctca aaaacactta
    12121 ttacagtatc ttagaaactt agacaataca taagattcat taataaaaaa gttctcaata
    12181 tagatatatt taaccatgtt ttgaatagca gataattata tgattaaaaa ttaaatatga
    12241 catagcgttt gtggaatata acacctaaat tatgttataa taataaaaca ggagtgtgat
    12301 agtgatggat gaaaaaatat tagagttatt acaggaaatg caaggtaata ttagtaatat
    12361 gcaaggtagt atcagtggta tcgaaggcac tattagtgat atgcaaagca atatcaatgg
    12421 tatcgaaggc actattagcg atatgcaaag caatatcaat ggtatcgaag gcactattag
    12481 cgatatgcaa agcaatatta atggtatcga aggcactatt agtagtatgc aaggcaatat
    12541 caatggtatc gaaaacacta ttagtggcat gcaaggcact attggcgata tgcaaggtag
    12601 tatcagtggt atgaatggca ctattagcga tatgcaaggc agtatcagta gtatggatgg
    12661 cactattaat agtatgcaag acagtattac tgatatgcaa gttgaaatta aagaaatcaa
    12721 tagtaggtta gacaatatgg aacctgatat taaagactta aaaactggac aagttgaaac
    12781 tagtagtaga cttgatacta ttcagagtga tgttacagaa attaagtcag atgtaaaaat
    12841 taacagaaat acattagata cagtgattaa acatacctct tcattagtaa aagatacatc
    12901 agatattaaa aatgatttaa ataatataga gatagtcaca tctaagaatt cgaatgatat
    12961 tgctaaatta aaatcagtta aataatatac tatagtaaaa aatacctgaa aatttcacat
    13021 acttctttaa agttatacca aattttatac agaaatactg attatccgac aacacacttt
    13081 acttataaat aatttattaa aaaaatactc attttatcct aaaattaaca cgactaaatg
    13141 agtcttgata taataataaa aaataaggga gattgaacac taaaaagttg tgtatctccc
    13201 ttatatccta taatatagtt atataatttt tcagcctaaa ataaaagtcc atctttgatt
    13261 aaaacacatc cccttatcac ttataaaagg ataaaatctt gttttcattt ttccatttat
    13321 atcttcttgc ttaagagtaa taattttttc ttttgatact ttaagtgttt ggttaaattt
    13381 aaccaataga ctaagttttg ttcaacatct atttttcata ttttccaata cttaatctat
    13441 tttttataaa taattctttc atttctaact cacttacatt ttttacataa aacgaagcat
    13501 ataaatttca accttatctt gtatggttct taatacttaa tgagtagctt aagtatcaat
    13561 cattataaat tttcccctta catttaacac tcttgccatt tccaaaatat acaaaatata
    13621 ttttgaacat ttgtacaatg atgaaataca atacatgaaa atacaatatc ataactcttg
    13681 tctaaaaata gaagttcttc aacataacct ttcacaaaaa acatattatc taagtatttt
    13741 ttgtctgctc cttgttttcc tttttgtagc atataaatta ctgcatctaa acatataact
    13801 actcacacga aaaaagaaaa taaacttcca aaatacaagc tctaaaaact acctctaaag
    13861 ttgtataatg tttactagga ataaggttgt ataacatata gtttaaataa tcatttttta
    13921 aaattgcaag ttattgcttt caaaattaga tgtttgtata tcaaataaat gattaagaat
    13981 ttctaaattt aatggcttta taatgcgctc cctttctttg gaataaaata atgttgcaca
    14041 gatacttttt ctaaagataa caattttatt tttctatcaa ttccaccagc atacccagtc
    14101 aaactcccat ttgttcctac aacacgatga catggaataa taatagagat tccattatgc
    14161 cctactgcac caccgattgc ttgtgctgac attttagata ttcctttttg ttgagcaact
    14221 ttatatgcaa tttctccata agtgattgtt ttaccatatg gtatttgttg taaaattttc
    14281 cacactgtag tctgaaaagg agtacctacc atatggagtg atggtgtaaa attgggttct
    14341 tttcccgaaa aataaatatc taaccatttc tttgtctgct cgaaaattgg caattctttt
    14401 tcttgatgtt cttggtcaag attataagca taatactttt gattctcaaa ccaaagacca
    14461 gttaacccaa tattatctga tgctaaaaga atatttccaa ttggactatg gtaatagcta
    14521 atatattgca tacaattcct ccttatattc tgaaaacttc actcaaatca ttagacactt
    14581 cttttctatc taccattatg taaaaacata ctaatataat ttccttctaa ctacactttc
    14641 gttataatat ctatcctcat atcatattag ttttatattt acctgcatct gttcatcctt
    14701 ttttcccttt ccctttgatg aatataaaat tcatacattt aagcttccta ctgtattaac
    14761 ttttatagaa gtgtatatta taattttatc accaaataga ccaaaaaaat atcgatataa
    14821 catcaagtaa tatcataata ctttcaaatg ggaaaagtaa gaataggctg taaaaaagaa
    14881 aagtattttt atgttagaaa tccagtaaaa tcgttagtag atagaataac agaaaacgaa
    14941 caatttgcta tttatcattt tacacataaa tataattggc gcaataaagt attttctatt
    15001 ctacaacgat taataaggtt agaaaaaagt aaaaatgaac tgtatatata tgaagcatta
    15061 gtttctgttt ctttcctttg gcttattatg ataacaaata ttgtttttcc accaataaaa
    15121 cacaaaaata taattaatat ccatatgcaa aaaattttac gttatattga aaaatactat
    15181 tgttttacat tatattgaag agtactattg tgaaaactta attttggagt actatcaagc
    15241 agtgataata tcaataaatc agagtgttcc agaggatttg aactaagttt aaatactata
    15301 ccttgtaaat attttattga gttttgttta ctaaaagcaa ctcaatttct aaaaggcaca
    15361 aatgagctaa taagtgacat tgctataaaa gttgtttttc atcaaataat ctattttagt
    15421 aaatgtttta aagaaaaaac gggatattct ccaaaagtgt acagaaatat aaaaaaagag
    15481 atatgatttt ttatttcttt tgattatcca aagagtaaat aaaaaatatt gtaaaaaact
    15541 tgctaacaac ggcaatgctt tgaactatgg taatactttg aacttttgat tggacttttt
    15601 ttgctaaaat aatatattta aatagcaaag taatctgttt aatcaataaa aaataagaga
    15661 taaaagaaat caactaaaac ttttacctct tattttgata gtttatcaga gctaatattt
    15721 acactctttt tatttttgat acttcattaa aaatgatgct tattctcttt tcatttttaa
    15781 tacttcatta gaacttatgc ttattctctt ttcactttta attcttcatt agaacttatg
    15841 cttactctcc attcactttt aattcttcat taggactatg cttattctcc attcactttt
    15901 aattcttcat taaaaatgat gcttattctc cattcacttt taattcttca ttaaaaatga
    15961 tgcttactct ctgttcactt ttaattcttc attaaaaatg atgcttactc tctgttcact
    16021 tttgattctt cattaaaaat gatgcttatt ctcttttcac ttttaattct tcattagaac
    16081 tatgcttatt ctccattcac ttttaattct tcattagaac ttatgcttac tctctgttca
    16141 cttttgattc ttcattaaaa atgatgctta ttctcttttc acttttaatt cttcattaga
    16201 actatgctta ttctccattc acttttaatt cttcattaga acttatgctt actctctatt
    16261 cacttttaat tattcattag gactatgctt actctccatt cacttttaat tattcattaa
    16321 aactgatgct tgcactctgt aaactcataa acatccatta atgcttcacc aaatctttga
    16381 tagtgaacta cttccctctc acccaaaaat ctcaatatat ctttcaaatc agggtcatca
    16441 gttaaattta ttaattgata gtacgtagcc aatgcttttt gttcagcagc catatcctca
    16501 tgtaaatcag ttaccgaatc gccaaagaca ttaatataac ttgtagtaaa gtttactcca
    16561 ttagaatcta ctggctgaag accatgtcca aaattagcat aattactacc aagtccagca
    16621 gccttaagct cttctggagt acaattgcct attaattgat ataacactga agaaattatc
    16681 tcaacatgag ccatttcctc tgtacctata tcagttaaaa gtgcacgaga ttttccagtt
    16741 ggcatagtat atctttgttg aagatatcta gttgcagctg ccaactcacc attaggtcct
    16801 cccaactgag tcatgatata ttttgccatt ctagggtctg cttgtcttat gttaactgga
    16861 tgttccagtg ttttttgata aatccacata ttatcttact cctccttaat atatatttaa
    16921 taataaatct aattttaaag tttaataatt ttatttataa aatgatttgt cccatggcca
    16981 aggttcagat atccatgacc aaggatattc acttgattca tatccaaaat tagttaatgc
    17041 tccatattta gattcataat cacacacagc ttgtgtaaat ttatcgcagt atctgttgta
    17101 tgaatcaaga gctttcttat cccttggatt gttatctaaa tataaattta attctataca
    17161 ggcaaattga tattctgaaa ttctctctaa aagttctctt ctatttaatg acattagtac
    17221 atgttacctc cttttttagc tctaactcta tttttaggat ttgcatatag ccaatcatta
    17281 tagttatttg actctattaa atctaattca ggaaataaag tacctctttt taatgctgtt
    17341 tttggattgt atgtgtcatc ataaatttga cgattgatgt atggtctagc aaattcacaa
    17401 caatagtctt gtttatcctc ttttaaatat cccattaatt atcctcctta atttttagaa
    17461 ttttaaaata gcattatttt taaaaattgt atactggttc tatattataa ctggtagttt
    17521 taataggtct ttaataagat taaatgatta aataagtatc tttttttctt attttacctc
    17581 taaaattttt ctaattaatc tttcataaat atctatttta aataaataat atagagttta
    17641 tacaattttt tatagcttaa ttactattta ctatatatta ttcattttta aataaaatgt
    17701 ga
//
LOCUS       DAEQAF010000079        17200 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.082, whole genome shotgun sequence.
ACCESSION   DAEQAF010000079 DAEQAF010000000
VERSION     DAEQAF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17200
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.082"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(114..638)
                     /locus_tag="KRN00_002756"
     CDS             complement(114..638)
                     /locus_tag="KRN00_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1828613.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQVMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(703..1455)
                     /locus_tag="KRN00_002757"
     CDS             complement(703..1455)
                     /locus_tag="KRN00_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1828614.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(1486..2784)
                     /locus_tag="KRN00_002758"
     CDS             complement(1486..2784)
                     /locus_tag="KRN00_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBH1828615.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYVTKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(2801..5065)
                     /locus_tag="KRN00_002759"
     CDS             complement(2801..5065)
                     /locus_tag="KRN00_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBH1828616.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKSNDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(5320..6138)
                     /locus_tag="KRN00_002760"
     CDS             complement(5320..6138)
                     /locus_tag="KRN00_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBH1828617.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(6131..6829)
                     /gene="cbiQ"
                     /locus_tag="KRN00_002761"
     CDS             complement(6131..6829)
                     /gene="cbiQ"
                     /locus_tag="KRN00_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBH1828618.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(6832..7116)
                     /locus_tag="KRN00_002762"
     CDS             complement(6832..7116)
                     /locus_tag="KRN00_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1828619.1"
                     /translation="MSAKTKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEI
                     TKINPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(7106..7858)
                     /locus_tag="KRN00_002763"
     CDS             complement(7106..7858)
                     /locus_tag="KRN00_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBH1828620.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(8040..8232)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(8364..10136)
                     /locus_tag="KRN00_002764"
     CDS             complement(8364..10136)
                     /locus_tag="KRN00_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBH1828621.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(10150..11079)
                     /locus_tag="KRN00_002765"
     CDS             complement(10150..11079)
                     /locus_tag="KRN00_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1828622.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            11307..11495
                     /locus_tag="KRN00_002766"
     CDS             11307..11495
                     /locus_tag="KRN00_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1828623.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            11488..12189
                     /locus_tag="KRN00_002767"
     CDS             11488..12189
                     /locus_tag="KRN00_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828624.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHCGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDCIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGQVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            12191..13114
                     /locus_tag="KRN00_002768"
     CDS             12191..13114
                     /locus_tag="KRN00_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828625.1"
                     /translation="MNTSVYLLLILVLSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            13271..14194
                     /locus_tag="KRN00_002769"
     CDS             13271..14194
                     /locus_tag="KRN00_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828626.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVIVISSQLCNDTLEDYFKKITGGEGIA"
     gene            14187..14924
                     /locus_tag="KRN00_002770"
     CDS             14187..14924
                     /locus_tag="KRN00_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828627.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPTKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            14935..15708
                     /locus_tag="KRN00_002771"
     CDS             14935..15708
                     /locus_tag="KRN00_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828628.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETKLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            15724..15876
                     /locus_tag="KRN00_002772"
     CDS             15724..15876
                     /locus_tag="KRN00_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828629.1"
                     /translation="MKKIKKLIILIVFLFLFGMLHCYTEWKFNNDPPKGVIERINEWT
                     DKIGLD"
     gene            complement(16249..16857)
                     /locus_tag="KRN00_002773"
     CDS             complement(16249..16857)
                     /locus_tag="KRN00_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBH1828630.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(17035..17151)
                     /gene="rrf"
                     /locus_tag="KRN00_002774"
     rRNA            complement(17035..17151)
                     /gene="rrf"
                     /locus_tag="KRN00_002774"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         5532 a         2984 c         2179 g         6505 t
ORIGIN      
        1 aaaagtgaaa tgtatttgtc taaaaacata ataacatttc actttatcct catttttaag
       61 taatatatat ttttaatttt tatttataac taaatctagt ttttatataa attttagttt
      121 ttttctacat ctgagtaatc tattccaaaa gtttctacag taacagattt cataacttgt
      181 ggagtttgtg gcttatcagc tgaatctgtt ctaactgatg ctatttcatc aactgtatcc
      241 ataccttcta tcactctacc aaaacctgca tactgaccat ctaagtgtgg tgagttttta
      301 tgcattatga aaaattgaga accagctgaa ttaggtgcca tagttctagc cattgatatg
      361 actcctcttt catgttttaa attgttagta aatccattac cactaaattc accttttatt
      421 gagtgacctg gaccacccat tcctgtacca tttgggcatc ctccttgtat cataaatcct
      481 ggtattactc tatgaaatat tattccattg taatatcctt catttactaa tgatacaaag
      541 tttttaactg tatttggagc tatatttgga tataactcaa ttttgatttc ttttccattt
      601 tccatttcta tagttactat aggattttta ttttccataa tttattacct tccttttcat
      661 tagttaaatt acataattac atttattata ttatactcta aattaaagtc tatcaagtat
      721 attttttcct atttcatatc cttcttgata aatagtttta caaaactcat catcaaagtt
      781 aagcgtgtct ttaggagcaa attgagtatt aggtctaact actattattt tatcttcatc
      841 atatactttt ttaatatctt ctggcaactc ataattatat tttgtggata ttaaaataat
      901 tttatccaca ttatccccaa ttaatggttc aattaatgca ctcctaatta aacctccatc
      961 taatttgaaa ccatcataaa ttccttcttg cacatctttc acaaattgtt ctttaaatcc
     1021 aagagttgcg tttggatttg atggtaacaa cccactgtat gaaatgctga taatggcttc
     1081 attacgaggc atttttgata cgtcaacaat cttttctgat actactttat tatcaacttc
     1141 aacataatta acataaaagt tcatttcttc tatattacta tcatctagtt cccttaggtt
     1201 gtctatagca ggagaattat ccacagtatt atttactatt tttacatttc cattctggat
     1261 atcttttata tttgtccaca ttttctccaa gttatcaaca ttccctgtgt acaaataata
     1321 tccatttatt gctcctattg atgtccctga aatcgaataa aatttattta ttcctccatc
     1381 atacaaggct ttaactactc ctgcttgata agcccctttt gctcctccac cttctaaaca
     1441 taatcctaat ttcatagtct catctccaaa ttgtttatct tatatttata tttcaaaaaa
     1501 cttactaaat gttttatata tactatagtg gtcctcaaca tttcctaatt ctcttataga
     1561 atgcattgct aaaattggac ttcccacatc cacagatggt atatctatat gagtagaaga
     1621 tattggacct atagtacttc ctcctctttc atctgaccta ttaacaaatt cttgatactc
     1681 aacattagct tctctacata tatttttata aatagctata gaatatccat cactagtata
     1741 tgcctgacta gcatttatct ttataaccgg accttttccc attattggtt tattagttgg
     1801 gtcatgcttt tctggaatgt ttggatgaat agcatgagct aaatctgatg atatcataaa
     1861 agatgaataa atagactcaa agaatccctc tctatcctta cccattgata tgcaaattct
     1921 ctccaatata tttaacaaca tgtttgaatc tgcaccttgt ttagtagagc taccaacttc
     1981 ttcattgtca aatacagcca ttacatttac accatgttga cctttagtat taacaagagc
     2041 attcaaacta gcatgtacca ttgcaagatt atcttgtctc ccaatagata taaattcatc
     2101 attagcccct attaaacttc ctttttcaaa ttcatataaa aataaatcaa aatctataat
     2161 atcttccata tttacatcta agttagatgc tatttgcttt ataagaaaat tatctttttc
     2221 taatgtatca tttaacatcc caactaaagg taacatatct ttttgcttat tatatgaatg
     2281 accatcattt atacttctat ttaaatgtat tgctagattt ggtattatac aaattggctt
     2341 tttaaagtct ataagccttt catttggttt taatatacta tcacctttta aaactactct
     2401 accagctatc ccaagaggtc tatccaacca tgtacttaat attgctcctc catagcattc
     2461 tgtatttaac ttcaaataag atttttcagc ttctatttct gcatttggtt taatactaaa
     2521 tgtaggagaa tctgaatgag agcctattat tctaaatcca tctctttcta taccttctga
     2581 atttactaca aaagctacta tagctgataa attcttagta acataatact ttccaccaac
     2641 tcttagattc catctttgat tcaaaactaa ttcttcaaat ccatttttat ctaagatttc
     2701 cttagtactc tcgactgcat gaaaagacga cggactatca tatatgaagt ctattaagtt
     2761 tttagcaaag tttatactat ccattcctca tttacctcca ttataaaata tttagtgttg
     2821 tatattcttt atttattttt ttaattccct gttggtcaaa agctatagta acatctgtac
     2881 caattataga aaccactgtc ccaaccccaa atttaggatg atgtacctta gaaccaagtt
     2941 ttatatcatc tggattagtt tctttattag aatcttttat tgtagcatta actttatctg
     3001 caactttaga tttgcttata gtactcatat actttttagt atatttatct aacatattat
     3061 aacttgcttt agaatagctt agttcttttt ttactttgta caatctttct atacattctt
     3121 ctggcagttc ttccataaat cttgaagcta ttgcaacatt tgttttacca tataatgttc
     3181 tcttctctgt caatgacata tatagctctt ctttagctct agttatacca acataacaaa
     3241 gtcttctctc ttcttctatt tgtgaatcac tcatagattt tatagctctt gatataggaa
     3301 ataacccttc ttccatacct gttaaaaaca caacagggaa ctctaaacct ttggatgtat
     3361 gaattgtcat aagcgaaacc ctatcattgt cttcttcatc atttgattca gatgtaagtg
     3421 ctatacttgt taggaatgtc tctaagtctt tattttcata agtatcatca ttactacttt
     3481 caaactccaa agctatagaa ataaattctc tcaaattatc aattctgtct tgagcttctt
     3541 cacctttgcc tgttaaatct ttttcatttt tatttcttat ctctacaagc tcgtccatat
     3601 atcctgtagt atccaagact ttttctataa gtttgctaac aggataaact tcttttatag
     3661 ttctaagagt ccctataata tcaacaaatc cacttatact tgcccttgcc ttagtagata
     3721 tatctgaatt tgtttctata tcaattaata ctgagtatat actttcctgt tttaagttag
     3781 ctctatcttc aattttttct atagttctaa gccctatacc tcttctagga acatttataa
     3841 tcctttttat agatatatca tcttgtggat tttgaataac tcttaaatac gccaacaaat
     3901 cctttatttc ttttctctca tagaattttg taccaccata tatattgtat ggaatttgac
     3961 ttctatttaa agcgtcctct acaggtcttg cctgtgcatt tgctctataa agtactgcaa
     4021 aatccttata aggtctattt tcttttctag ctatttgtgc aattgaatca gcaatgaaat
     4081 cagcctcttc tatttcacta ccagttaatt gtatctttat aagttctcct tctttttttt
     4141 cactccaaag cttttttctt tttctttcta tattattaga tatgacttta ttagctgcat
     4201 ctaatataac ttgtgtagac ctataatttt gttctaactt tacaacatgt acattgtcat
     4261 aatctttctc aaattcaagt atgtttctta tatctgcacc tctccatcca taaatacttt
     4321 ggtcatcatc tccaacaaca caaatatttt gatgttctct tgctaataat tttatcaatt
     4381 catattgagc tttacttgta tcttggtact catctaccat tatgtatcta aatctacttc
     4441 tgtaatatgc taacacttca tcattagact tgaaaagttc tacagtttta agtattaaat
     4501 catcaaagtc aagtgcacta tttcttttta aacggtcttg atatagcgca taaatatctg
     4561 caatcttaac cattctatta tctgccatat tgatatcttt aaactgcttt ggagtataaa
     4621 gtttgtcttt tgctcctgaa attgcactta taactgcttt tggttcaaac actttatcac
     4681 ttaaatttaa ttcttttaga cagtctttaa ccaatgtaac ttggtctgct gaatcataaa
     4741 ttacaaaact tctattgtaa ccaatcttat ttatatcttt tcttagtata cgaacacagc
     4801 aagaatggaa tgtacttatc cacatatcct tagtttcagg acctatattt tgttcaactc
     4861 tctctctcat ttcatttgca gctttgtttg taaatgttat agctaatata tttggtgctt
     4921 gtacaccttt atcttctata agatatgcta ttcttgttgt taatacctta gttttacctg
     4981 aaccagcacc agccagtata agtactggac cttcagtctt ttctactgct tctctttgag
     5041 caggatttaa tgtatctaaa ttcatatttc tcctcctgtt aacagccata aatatatttt
     5101 aatctaaaat atgaattact tcaaattata attatgtatt atattaatag attatttcca
     5161 atatattaca attaaataac atttttccat ataatttatt tcattgttta ataaaaaaaa
     5221 taaccttatg atttggggaa tcataaggca cctttaaggg gtctaggtta agggttatta
     5281 tatataaatc tattttttta aaataggttt agggcttaat tatttatttg tattaagttc
     5341 tctttccttc caatacttat acaaatcttc ttctttctta aataagggta aattcatatt
     5401 tctatgtact tttactaacc atggggattc tagaccagct tgtataatat tattttcatt
     5461 tataaacaca ttttctgctt ttccttcatc aatcaaaatc cccttatcca atacatatat
     5521 gtaatcacat atttcataca ttaaattcat atcatgactg gatattacta tttttatatt
     5581 atttttattt aatcccttta ttatatctac aatagaccta gtacttactg ggtctaaacc
     5641 agctgtaggt tcatcaagta atacaatttc attttccatt gctataactg atgctattgc
     5701 cactcttttt ttctgtccat agctaagaaa atgtactggc ctgtctataa aatctattcc
     5761 attaacagct actagagctt tgtttattct ctctttaatt gttttttcat ccataccaat
     5821 gtttctcatt gcaaaggcta tatcatcata tacttttgaa taaaaaattt gtttttctgg
     5881 gtcttggaac acaataccta cattttttct aaggttgtat aaacttctct tatcatattt
     5941 taacttttct tctttaaaaa gaatttctcc agatgtaggc tttaatatac ccattaaatt
     6001 cataaataat gttgattttc ctgaaccatt tgaacctatt atacctataa catttccctt
     6061 tgaaaaatcc atattaatat ttaatagtgc attggtattt ttttcatatt gatacgttaa
     6121 attatttatt ttaaacatca ttatccccta ctatgtgaaa tttaccatca tacaatttta
     6181 tgtctaatga tatacacata tcatcatacc ttgtcataag tcttttgtac agcatacttc
     6241 caagaatacc taaggattta tatgaagttt ttaaatttat atatccaaat cttagctctt
     6301 gtgacttgta tatttctgaa aattcttcta aaaatatgaa tataaaccta tatattaaca
     6361 ttgataactc gacaaaagtg tcaggtaaat gaagtttttt aaaaaagaat attaattgat
     6421 taaaaggtgt tgtaagtata caaaaataca cacaagtcaa acaagacatc gctctaaata
     6481 acacatgaat agacatgtca atagacgcct ttgatattcc tacattaaaa ctaaaaaatt
     6541 caaaactata taataaatct gctttattaa aagatatatt tacaagagtt attcctatac
     6601 taagaaataa aaagtacatt ggtattctaa gtaattttaa ataatttttt aaatctattc
     6661 cagccacaca aacaaccaaa atactcatta aaatcataat tccacttaaa ataaatatat
     6721 tttgtattac catagaagca atcagaaaaa ttactcctat ggctactttt ttgtttggat
     6781 ttactttact caatctattt gtatatgcat atttatcaat tataagcatg attaacttct
     6841 ctttcctttt tgaagaccta atatgtatcc tattacacca gcccctaaag ctgcttgtgc
     6901 agagaataat aaactttcta tttctccact tggtggctca tatggactgc taaaccatgg
     6961 tttgtaattt ggatttatct tagtaatttc actttcagct tgaccatctg ctcctccata
     7021 ttcagcacct gagttgacaa gtaatgggaa tataataaga gctactacta ataaaagtaa
     7081 taatatgtta gtttttgttt ttgttttagc actcattagc tttaactcct ttatcattat
     7141 tttctagtat gcttttttct ccgttttctg taattaaatt atatacaatt acagtaagta
     7201 taccttctgc tattgctatt ggtatttgag tcataaagaa aattcctaaa aatttaattg
     7261 ctgaagccat taccccacct gatgggtctg ggaaagccag tgctaattgt attgaagtta
     7321 ttgtatatgt ggctaagtct cctattgctg ctgcaagaaa tactggaata gcattatttc
     7381 catctttttt ctttaaagcc ttaaatatta ggaatgatac gattggccct attatcgcca
     7441 ttgaaaaagc attagctcct aaagtagtta ttcctccatg tgctaataac aatgcttgga
     7501 atattaaaac tatagttcca agaacaaaca ttacgcttgg tccaaacatt attgctccaa
     7561 gacctacacc agtaggatgt gaacaacttc ctgttactga aggtattttt agtgctgata
     7621 atacaaacac aaatgctcca cataaagcta ataatacttt ctttttaggg tcttgcttta
     7681 ctattttacc tattgatttt aatccgaata agaaaaatgg tataaatata actccccatg
     7741 ctatagacca ttttactggt aagtaacctt ccattatatg cattgcattt gatgtaactg
     7801 gagttaaaat gattaacata agtgcagcta taacccctaa tttaatattc tgtttcatct
     7861 tagtatccct ctctcccttt ctaataatta aaacataata atacatgtct gatttattta
     7921 ataaaataaa aaagcctaac tcgatggtta ggcttctaat tttccacaat ctaaatacaa
     7981 acacataaaa caaacatatc tgtataatta ttataagaaa ctttctccat ccccgaagaa
     8041 attactttaa tattttaggc aggtctcctg acttagcttc atcctactcc ttttccttcc
     8101 catgagatat aaaaaatatc atcatagtgg ctaacaaaag tttcgtctgc atcacagtag
     8161 cgggggctgt aaaggaattt aacctttttc cctattaatc ttgcttaaag aacctataat
     8221 attatatatt taatttttaa attattctta aattattttc tatataaatc attgtatacc
     8281 ttttctgtga aaatttctac attttttata aattttattc atttttatat ttttatgtat
     8341 ataaattctt ttttgtaagt ttattaattt ctaattatct tctttaaata cattgaaact
     8401 acatcagaaa atctagttat atctcttgaa tatataaaat catttccata tattaatctt
     8461 tcagcttcaa gttctgattc ttttcctgta aatactccta atactaatat attttgcttt
     8521 ctagcttttc tcacttcatt ggctgtatct ctcaaaccaa ctatacccct ataagccttt
     8581 tctcctctta atgttctctc actacttttt cctatcttta catcatttgg tcttccatcg
     8641 ctgagaacta tcaggatttt attttcttca tctctattta ttagaccact acatatagat
     8701 tttattgcca aaccatctct attattacca gcacaaaaat attcaaatat attttcacta
     8761 ttttttatac tatcatcata atctttaaat ctttttaata ttgtatagtc taaaaaacta
     8821 gaaaatccca tcactctatt tggtatgcca acttctgtta gagcatttgc aattatgtaa
     8881 gcttgaattg ccacatttcc ctgatttcta ctttgagagc cacttgcatc caataatata
     8941 tcaataacgt atttcccttt ttcattttct atatctttat aaaatatttt attattatta
     9001 cttctaccaa ctctccaagc tctatttgct aatatagtac cacaatcaga atatactcta
     9061 cttttagcat tttcttctat taaaattctt gacagacttt cttttaatct ctttatttgc
     9121 tgtctataca ttctagcatg ttctctaaat tttcctaaat tattttcttt ttgtcttgtt
     9181 acatatttta gttgaaatac attattacac tcacttctaa gaactccatc tgtaaagtgt
     9241 attctacaac cttcatgaac atttctacaa ttttgtgtct caattttttt aatttcacct
     9301 ttactcaaat aagtttttcc ataataatgt tctatttttg aatatatctt atttgcagtg
     9361 tcttcatcaa catatataac tcggtctgct gaattgctac atttagaatc atcaaaatcc
     9421 cctacacctt ctacaagcat ggatgaagat attgaatcta tatcactttc aataatattt
     9481 tcttcttcat cactataaag ttcttcatac atgaaatcag caaatgtatc aaaatttact
     9541 tctacacttt ctacattatt ttcatcaata agactatttt cttctccatt taatatgtat
     9601 tcaaaataag ttaaatatat aacatctaat gcttttaaaa tctccataat atcttgattg
     9661 gtatctatat ttcttatatc attaactatt cttctagtca tactatctaa tgctgggtgc
     9721 ttgtccatac tataaagtac aaatgtgtat ttaattttat ccataatatt atcattgtgt
     9781 attttggtaa aacgtgaaac aatatcttta taagcatttc ttcttatgtc ttctatccct
     9841 ggcctatctt taatgacctt ttcttcaact attgtattta atatgacttg aattagaccc
     9901 agtataatat ctttgttgta tccttttctt attctatttg taagatattt tttaactata
     9961 tcccaatcta catactttct tctagcacct gcaattattg cgaaatatag acctatttct
    10021 tttgaagagt aatctttttc tgatatatct atactttcat tgtaatcacc agctattgtc
    10081 catgataggt tattagctct attttcaaat tcataatcat catatatcca tttcataatc
    10141 tcacctatat taaatatgac ttattggaaa cacatctata ctctcccatt tattaggtat
    10201 tctagtttta attacatctc caaccatttc tttctcatat acatcaaaag tctttcctgt
    10261 aagtcccata ttaattgcaa gagttggttt taatcctctt cttatagtct taagagatgc
    10321 cataagacca cgtaaatcaa tagctttact agatatctct ccattttgag acttcaattg
    10381 taaatctaaa aatattcctg caaagtgtat taatttttct tcatcagcat ctgaaaattc
    10441 attttttaaa atcatcatta acttatcttc ttctatagga ggaatatcta ttaccataaa
    10501 tctagatacc agtgcttcat taagttcttt tgttcctgca tattcataat tcatagtccc
    10561 aataaatctt gttgctggat gtagattgac tctctcatac ccaggtacat caattattct
    10621 tctatagtct aaagctgaat gtaccacaac tatagcatca ttttttgcca tattaatttc
    10681 atcaaatacc ccaaaacctc cattaatagc acactcataa actgagcctc ttctaagttt
    10741 aacttcattg tctataaatg tatctgtacc tataagtgtt gaactgtctg tatttatatg
    10801 aaatgatgta ttccactgag gtctattaaa tatttcccct agattatcag caagtaagtt
    10861 ttttcccgtt gcctttggtc ccgataataa tatattttct tcttctaaaa tagctgctat
    10921 acacatagac aagatatctt taccataaaa ataagtttta gactttgtta ctctgtattc
    10981 taaatctttt tctaatccat aataatttct aaaatacagt acatcttcaa taagtttttc
    11041 atctacccct tgcaccctta gattatctat tatatccata tttttacccc ttttatataa
    11101 atagtatttg tttcatttct tatcaccatt ttagcataaa aggatataag ctaaaattga
    11161 ttttttaatc tccccatttt aagtaaaacc atgcaccatt ttatcactac aaaattaaga
    11221 gtactactta ctgatatttc ttgattttgt tcgtctatac gtatataata tatgctgata
    11281 aattatgagg aaaggatgat tgaaatatgg aatatatgtc ttgcccagaa gtagcaaaaa
    11341 aatggggtat ttctgaaaga agagtacaaa aactatgtga agaaagtcgc ataccaggag
    11401 tttcaaaact cgggtatatg tggctgatac caaagaacgc agaaaagcct gttgatggta
    11461 gaacaaaaag aagaaaggaa gtacaatatg aatagcgttt tgattataga tgatgacaaa
    11521 gaactttgtg ctcttatgaa aaaatgtgtt gagcaagaaa atttatctgc tattactgca
    11581 cattgtggtg cagaaggtct acatttggtc gataaaaata gacacacact ctctcttgta
    11641 attttggaca taatgatgcc agatatagac ggttttcaag ttctgaaaaa aattagagaa
    11701 acaagtaata ttccagtaat tatgcttact gctaaaaatg acgaggatga taaagtttcc
    11761 ggactacgtt taggtgctga cgattaccta acaaaaccgt tcagcataaa cgaacttatg
    11821 gctcgtgtca attctcttat tcgtcggtat actatgttaa accctgcttt tataacagac
    11881 acagattgca taataataaa tggcatgatt attgacaaga caaaccgaat tgtttctgtc
    11941 aataatattc ctgttcaact tacaagcaaa gaatttgatt tacttgcttt tctggcttct
    12001 aataagggac aggtgtttac caaaaaacag atttatacac aagtatggga agaagaatat
    12061 gcttttgacg atagtaacat catgtctttc atcagtaaat tgagaaaaaa gattgaacca
    12121 gaccccaacc atccatttta tattttgaca gttcgtggtg tcggttatcg ttttaataag
    12181 gaggcttaac atgaatacaa gtgtctatct gcttttgata ttggttctta gcctgattat
    12241 tatagcgtac cttgtttctg tcctgctacg tgtccgaata caacttacac ttataaaaga
    12301 tgctttagag gatataaaaa atggaaacct taatcgacgt attttaacag atgaaaacga
    12361 cattacaaaa caaatttgct atgatattaa cgaaatagca atcaatagcc aatttcaact
    12421 tattcagcaa aaacaatcag aacaagccta caaacagcta atgacaagtc tctcccatga
    12481 tgtaaaaact ccacttgctt ctttggtcgg ttatttggaa gcagtagaaa gtaaaattgt
    12541 tgtaggagag gaaaaagacg agtatatcca tgttgcgtct aataaggctc attacttaaa
    12601 gaattttgta gaaaatctat ttgaatgggt aaaattggat tctaaggaac aagtttttca
    12661 ttttgatatt tttgacttga atgaattatc ccgtaatatt atatctgatt ggatacctgt
    12721 tttagaaagc agtcattttg aatatgaatt tgatatacca gaaatagagt acttcttacg
    12781 tatagacgca aatgcatata cccgtatcat taataaccta ttacaaaata ttattaccca
    12841 tagtagtggc aacaaaatga cattgagaat ttttgaaaac aaagagcaag ctcaaattat
    12901 aataacagat aatgggaaag gtatatcttc agacaatctc ccacatattt ttgaaaggtt
    12961 gtaccaatgc gaccattcac gagcttcaaa gggaaatggt ttaggcttgg cgattgcaaa
    13021 ggaacttatt aacgctcata agggaaatat taccgccaac agcactcccg gtatgggaac
    13081 agaatttaca atattgcttc ctaaagccct gtaaaagtac gaggctttct tactctaaaa
    13141 caagataaaa gcaagattat ggcaaggttt tggcaaggtt catgttttat aattctaatt
    13201 gtagttgatt ttgacgttgt atcaactatc ttttgtagaa acaaatttat taaaagtgag
    13261 gaaattatat atgaatgatt ttgtgattga aacaaagcaa cttacaaaaa tttatgggaa
    13321 tcaaacagta gttgacaaag tcaatctcca tgtaaaaaaa ggccgaatat atggtctgtt
    13381 aggacgcaac ggagctggga aaaccacaat tatgaaaatg attttaggat tgacttcaat
    13441 cacgtatggc gaggtagatg tatttggaga gaatattaag ggacgtgaaa aacaagtata
    13501 tccccgtatc ggtgcaatta tcgaaacgcc aggattttat cctaatctga caggaacgga
    13561 gaacttggag atttttgcaa aactgcgtgg tacagccgcc cctaattctg taaaaagagc
    13621 attggaaatt gtaggcttac cttataaaaa taaaaagctg tttagtaaat attcacttgg
    13681 catgaaacag cgacttggta ttgccaacgc tatcctgcat gacccagaac tgttagtttt
    13741 agatgagcca accaatggtc ttgaccctat tggtattgcg gagatgagaa agtttattag
    13801 ggacttgagc gttgagcatg gaaagacaat tcttatttcc agtcatattc tttcagaaat
    13861 ctcattgttg gctgatgata ttggaattat cgaccacggt gttcttttgg aagaaagtag
    13921 tatgagtgaa ctagaaaaga aaaacagtaa atatatcctg ctacaagttt cagatattcc
    13981 gaagacatca cttattttag agcgtcaatt taacacgaag gattattccg ttcaagatga
    14041 ctacacgtta cacctttata acactaatct ggatatgggt gaaatcaata aagcacttgt
    14101 aatgcagaat gtaattgtta ttagttctca actttgtaat gatactttag aggactactt
    14161 taaaaaaatc acaggaggag agggcattgc ttaaacttat tcaaacagaa tttcttaaac
    14221 tgcgtcgtag gaaacttatt tggctgatgt tgttgtctgc tctcattatg ccgtttttcg
    14281 cactactata cttcaattat tttggtaaaa caggtgttga gccaacaaag ttttataaat
    14341 ggtctgcatt tggttataca ctttggatta ttttgcccgt tgttttgggt atattttgca
    14401 ccatgcttat acacgaagaa aaccagtatg atatgctcaa acagctttgg attgtaccta
    14461 ttagtaaaat gggatacttt tttagtaaat ttttcgttgt tttgatttac tctatttgtt
    14521 ttatgctgat tacagccgtt gcttctgtgt tatttagtgt actttctgga tatgtcgtat
    14581 ttagctgggc aagcatttta tatttgttga aaaaatgttt agaaattggt gtaatcactg
    14641 cttttgtaat gttgccgatt ttggcaatcg ctacatctca aaaagggtac attctcccaa
    14701 tttgtatcac attggtatat gccttttccg gttttgttat aatgacaata aatatgtatt
    14761 tacacccatt atccagtatg ggagttatta tcatgagaaa taaagacatt ccaggtctta
    14821 tattttcaca ggaaattaat gtcccattag catttctttg tatttgtatt tggagtattg
    14881 tatcagtatt gtttgcaaac attgcactag gaagaagaaa gtgaggtgta gataatgtgg
    14941 aaattacttt gggctgaatg tcaaaaaatt cgtcgttcaa aaattgtttg gattacagtt
    15001 tttgcatcca ttatgatagc agtcatagtt tttgcaggag ggcaggatgt atataatgac
    15061 ccagatttac attatggctt aaagagcgtt tatgacggtt cacggtatat agacaatgca
    15121 ggttggtata tggacgcagt acaaccttgg tcaacttttt ttgttcttcc tgctgtcatt
    15181 gccctattag gaagctatat tatttgtcgt gaagaagagg aggacactat taaatccctg
    15241 cgtcttattc ccataaatga aacaaaatta accatagcaa aaatgattat tacttttata
    15301 ttcagtatac ttctttattt gttactcttt actataacat ttttgactga atccgtttta
    15361 catttttctg atttatcgac aaaactggtt ttaagttgca tgaaagagta ttttcttgat
    15421 ggcataggtg tattctttgc aatttctccc attattgcct tggtatcgcg catgaaaaaa
    15481 ggatattggc ttgcattagt attcacagaa gtttattcta ttgctggact atttgcgggt
    15541 atgtcaaatg tcttacaaac cttttttcct attgcggcaa tatttaatat ttctggatac
    15601 tatataacta ctggagaaaa aattatgggg agtatcataa gtttattact ttgtgcctgc
    15661 ctttctgcat ttatactgaa agggctaaaa cacaatgaaa aaaattgaaa tatgtatatc
    15721 aaaatgaaaa agataaaaaa actgattatt ctaattgtat tcttgtttct ttttggcatg
    15781 ttacactgtt atactgaatg gaaattcaac aatgacccac ctaaaggggt aatagaaaga
    15841 ataaatgagt ggactgataa gattggactg gattagtaac ttatgttaat tatagtgaat
    15901 gtaatattag caagttattg tttcgtattt taatactata actttaaata tttggtttta
    15961 atcttccaaa cgaatataaa aaaactgtca cagaggcaac atatttttga atatttataa
    16021 agtggtagtt ttgattttca aagctgccgc cttttcttct atataagcaa acttatcctc
    16081 aacaaagtgt aaaacatggt acattttaag aaaaaagtac cacagacaca agcaataaaa
    16141 gaaacgccga gaacctacaa aaacgtagtg cttatgcaga tttacgacgc cttctatttt
    16201 ctcaaccgtc ttaatgacct tgtacaaaag aaatttttct aatatttttt ataatcttat
    16261 cttgtgatgt tttttatgta taaatgactt aataacaaat ccaataaaaa ttatggatat
    16321 tggtataatt agaacgagga atttataatc attataatgt gacattattc ttacccaact
    16381 ctcagaaaaa atatatccta tactgattaa tgaagtattc catatggtta ttcccacgat
    16441 agatgatatt acaaaagtta taatattttg acctgctata cctgctataa aagatatgta
    16501 tgttctacat aaagggatta atctacatac acaaacagaa atagaagagt atttattaaa
    16561 ataatcttga gatgcaaata ttcctttctt tgcctttgga catatctcta ttattttatt
    16621 tatgatagat ttacctcccc aatttcccac tgtataacaa aatatcgaac caagtatacc
    16681 tgcaattata cttaaaatta aaattgtcag aaatccaaaa tgatttcttg cagcaattgc
    16741 tccacataaa ggtaaaacaa cttcgctagg taatggaaaa caagcatact caatcataat
    16801 taatacaaat acagagatta atccatattg taaaataaaa ctattgatta cagacactta
    16861 cttatctatc tcctttctta tttaaaggtt ttaagggtac atattctaag gattctcacc
    16921 ctatatttaa agaatcaatc tctttaaact attatatgta tttacacaaa gcatttataa
    16981 catactttaa aaatagtacc ttaaaataag aaacttaata aataaaaaaa gattacgtgg
    17041 ctacgtccta ctctcccagg cagtttccca ccaagtacca tcagcgctag agagcttaac
    17101 ttctgtgttc ggaatgggaa caggtgtatc ctctctgcta ttgtaaccac ataatcttta
    17161 tgcttaatat ttctattaag tttttaataa gtttatagaa
//
LOCUS       DAEQAF010000080        17065 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.083, whole genome shotgun sequence.
ACCESSION   DAEQAF010000080 DAEQAF010000000
VERSION     DAEQAF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17065
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.083"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            115..744
                     /locus_tag="KRN00_002775"
     CDS             115..744
                     /locus_tag="KRN00_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828631.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIIAECEPQLEYVK
                     KQYKEYTKKTKNTMLDCRCPESISLLKRNNLINDFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            745..1527
                     /locus_tag="KRN00_002776"
     CDS             745..1527
                     /locus_tag="KRN00_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828632.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            1520..2398
                     /locus_tag="KRN00_002777"
     CDS             1520..2398
                     /locus_tag="KRN00_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828633.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNEEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRISSKIVNDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            2431..3390
                     /locus_tag="KRN00_002778"
     CDS             2431..3390
                     /locus_tag="KRN00_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1828634.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKELIYNAK"
     gene            3704..4396
                     /locus_tag="KRN00_002779"
     CDS             3704..4396
                     /locus_tag="KRN00_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828635.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDIVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            4406..5410
                     /locus_tag="KRN00_002780"
     CDS             4406..5410
                     /locus_tag="KRN00_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828636.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            5658..6509
                     /locus_tag="KRN00_002781"
     CDS             5658..6509
                     /locus_tag="KRN00_002781"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBH1828637.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            6613..7359
                     /locus_tag="KRN00_002782"
     CDS             6613..7359
                     /locus_tag="KRN00_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828638.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            7359..9275
                     /locus_tag="KRN00_002783"
     CDS             7359..9275
                     /locus_tag="KRN00_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828639.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDPKKPD
                     SKEKDKERMMFIENNLKKENVDYTRTNGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     VKPISFEDNECISLLSSSLPGNNNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            9547..9780
                     /locus_tag="KRN00_002784"
     CDS             9547..9780
                     /locus_tag="KRN00_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBH1828640.1"
                     /translation="MMILIQSRGKMKCKELPEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEINKCNSISLIKLLDSEVSIFISTKW"
     gene            9976..10404
                     /locus_tag="KRN00_002785"
     CDS             9976..10404
                     /locus_tag="KRN00_002785"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBH1828641.1"
                     /translation="MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKSFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     gene            complement(10859..11638)
                     /locus_tag="KRN00_002786"
     CDS             complement(10859..11638)
                     /locus_tag="KRN00_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828642.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTSYCCGNCDSEINLSQREHFKI"
     gene            11962..12507
                     /locus_tag="KRN00_002787"
     CDS             11962..12507
                     /locus_tag="KRN00_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBH1828643.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            12539..13675
                     /locus_tag="KRN00_002788"
     CDS             12539..13675
                     /locus_tag="KRN00_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBH1828644.1"
                     /translation="MEEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYDTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            13679..15070
                     /locus_tag="KRN00_002789"
     CDS             13679..15070
                     /locus_tag="KRN00_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBH1828645.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENLLSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKKLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRTIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDIINIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            15146..16021
                     /gene="dpsA"
                     /locus_tag="KRN00_002790"
     CDS             15146..16021
                     /gene="dpsA"
                     /locus_tag="KRN00_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBH1828646.1"
                     /translation="MSNQYDITVIGGDLRQVYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     PTKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            16024..16614
                     /locus_tag="KRN00_002791"
     CDS             16024..16614
                     /locus_tag="KRN00_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBH1828647.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(16821..17021)
                     /locus_tag="KRN00_002792"
     CDS             complement(16821..17021)
                     /locus_tag="KRN00_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828648.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
BASE COUNT         6650 a         1753 c         2829 g         5833 t
ORIGIN      
        1 aaatgtagat aaaaattgtt ttattaagaa aaaattaata tattgacaaa atttaagtgc
       61 tcatttaaac tattaattga taataatatt caatattaaa taataggagg cgttatgaat
      121 aaatatcttc taataaatcc agtggcagaa agaatgtatg gagaaaagtt tcaccttatt
      181 aaagcaaatt tgataaaaaa ggggtacata atagcagaat gtgaaccaca gttagaatat
      241 gtaaaaaagc agtacaaaga gtatacaaaa aagactaaaa atacaatgtt ggattgtaga
      301 tgtccagaaa gtataagtct tttaaaaaga aataatttga taaatgattt tgaagtacct
      361 atgatagaac caatattagt aaggacttgt agggttttat acgataaata tataaaaagt
      421 aaagatgata tgttggtagt aacctgtcca tgtacacaat taagagactt tgcaagtgaa
      481 aagtttaagg ataagggtaa tgctatgttt tatacatgga aagagtttgc tgaacaagaa
      541 ggtgtaaaat cacttggaaa aatagatgaa tcaccaattc cattaggata tttcaaagat
      601 acttttgaaa aagttcttga agtatcaagt gaagacgaaa tattaagtga aatacaaaaa
      661 ataagaaatg gctttgaaga taagtatgac atagtagaaa tgttttattg taaagatggt
      721 tgtaataatg gagatggttt gtaaatggtc aataaattta ataataagtt tttaaggcta
      781 gtaaagagtg ttctgatatt ttttataatt cttttattat ggaaaattac aaattatctt
      841 ggtatttgga gtgattatat attaccatca cccgaaaagg tatatagtac atttttaaat
      901 atgataagtg atggttcaat atttattaat gtatatgcaa gtatgaaaag agttttgata
      961 ggttttgcaa taagtactgc tataggtgtg cctttaggga tattctttgg aatttatagt
     1021 ggagtatatg aatactttaa atctctaata aattttttaa ggaatacacc tccccttgct
     1081 ttaataccaa tgcttatatt atggtttggt ataggagagg aatcaaaaat tataattata
     1141 gttttagcat cctttttccc aatctttaca agcacattga aagggattaa aaattgtgac
     1201 tcaaaactga ttgaagtggg tagagtattt gagttttcaa agcttcagat aatatttaaa
     1261 ataataatac caaatgccat tcttgatatt gctgttgggt taaagttagc tcttggatat
     1321 agctttagag caattattgg ggcagaactt gtagcagctt catctggtct tggatacttg
     1381 atatctgatg gaaaagaaat gtctagaaca gatgttgtta ttgtaggtat aatcgtaatt
     1441 ggacttttag gaataattac agattacata ttttcgatta ttgtgaagaa ggtaagtaag
     1501 ggaaagatgg tggaagcata tgaataattt agtatgtgac tctggatata taattagaaa
     1561 tttatataaa agttataaag ttgacaatga agaacatgta gttcttagtg atatctcttt
     1621 aaacatagat agaaaccata taacagtaat tttaggtgaa agtggttgtg gaaagactac
     1681 cttgcttaga gcaattgcat cacttgaagg tataaatagt ggtgaaatta ggtttattaa
     1741 tgataataaa gagtatagac ctaatgttgg ttttgttttt caggagagca gattaatgcc
     1801 ttggttaaac gtaagtgaaa atatagcttt tcataatcaa agaaaaaata ctattttaaa
     1861 caaggtgctt agaaaattta aacacaataa aagaattagc agtaaaattg taaatgataa
     1921 ttttagaagc ttagaaacaa acgataattt aaacaaatca aataaatata ataggaaaag
     1981 taatattgat gtagaaaaat atcttaagat gatgaacttg cagaaattta aaaactctta
     2041 tccaaatgaa ttgtcaggag gtatggcaca gagagtaagc atagctagag ctctttcttt
     2101 caatccagat atgttgctta tggacgagcc tttttcggca ttagattatt ttacaaggat
     2161 tgatatgcaa aatgaagtta taagaataca taagtcaact aataaaggcg tgatatttgt
     2221 aactcatgat attgatgaag cgttaaagat aggcaagaaa atagttgttt tcacagacga
     2281 aagaaaagta aaagaattta atatagaaga tggttataat agagatttaa cttcagatta
     2341 ctatattaaa ttaaaaaaag atattttaat gacaatgaaa tcaaataaag gcatttaaag
     2401 aaattaataa tattttaagg agtaaagtaa atgaaattaa aaaagctatt gataggtata
     2461 acgatattga cacttgcaac agcatcttta gctggatgtg ctaaaaaaaa taatggagaa
     2521 aaactttcag aaataaattt aacttatgta aaatcaccat taaatgttcc ttctataatt
     2581 cagaaacagg atgatttatt tggaaaggaa tttaaaaagg ataatataaa agttaacttc
     2641 cacgaaatta ctacaggtcc agagcaaaca caagctttag ctgctggaga aatagacttc
     2701 ttacatgcac taggtggtac atcagcttta atagctgcat ctaatggagt agagttaaag
     2761 atattaaaca cttatagcag gtcaccaaaa ggatttatga ttttgactaa taataattca
     2821 ataaaatcag cagcagattt agtaggtaag aaggtggcag gcccaaaagg gactatatta
     2881 catcaggtat tgatttcagc acttgataaa gaaggattaa gtatggatga tgtggaattt
     2941 gttaatatgg gtattccaga ggcatcagca gctctttctg atggcagcgt agatgctgca
     3001 ttgattgctg gtccagcagc tcttaaagct atgaagtcag gtagtaaact tgtagcaaat
     3061 ggtgaaggtt tagtagatgg tataatagta actgctgtta gcacagactt tgcagagaaa
     3121 catccagaaa tagttgaaag atttatgaag gttgaaaagg aaactttaga atatgtaaat
     3181 aataattttg atgaagctat ggaaaaagta gctaaagaag ttgatttaag tcttgaagaa
     3241 actaaagaat tatatgcttg gtatgatttt agtttagata taacagataa agacatatct
     3301 tcgcttgaag atacacaaga cttcttaata aaaaataagt tacaagagaa aaaagtgaac
     3361 ataaaagaat taatctataa tgctaagtag aaactatgat aaaataatac taagtaagaa
     3421 atataataaa agtttaagtt accttattaa ggtaactttt tctattttga attagtaatt
     3481 tcaatttatt ttagaatgat tagttgataa taatgattaa ttaatcataa aaagatgctt
     3541 ttttatagag ttttattaag atgtctaata atatggttat acttatgaag tcagtaattg
     3601 tgaagttagt aatatgatta aatttatata ttgtaaaaag attataatat attaaaattg
     3661 gactgttata tgatgagtaa ataggtatat taggagggat tatatgagtt ataaagtata
     3721 tattgtggaa gatgatatat caataagtac attacttaaa gattatattg agaaatatgg
     3781 atttgaagtg attgttgaag agaactttga tgatataatg attacatttg aaagttttaa
     3841 gccacactta gttctattag atgtaaattt acctaaattt gatggtttct actggtgtag
     3901 atgtattagg caacagtcga atttacctat aatttttata tcagctagag atggtaatgt
     3961 agaccaaatt agagctttag aaagtggagc agatgattat ataacaaaac ctttttacta
     4021 tgatatagta atggcaaaaa taaagagtca tataagaagg gtatatggtg aatattcacc
     4081 taaaatagac gaaagaatag tggagctaga tggattaaag ttttatccag aaaggttaga
     4141 actagaatta aatggtgaga atctaattat aactaaaaaa gaaggtatac tgattgaatg
     4201 tcttatcaag agatacccaa aagtagtaag tagagattat cttttagaaa agatatggga
     4261 tgatattgag tttgtagagg aaaatacttt aaatgtaaat gttagcagga taaggaaaag
     4321 atttgaggaa ttaggtatag ataatgctgt tcagactgtc cgagggttag gatataaatt
     4381 aaataagaat tggtaaggag aaagtatgaa gttattttta aaagattata aaggttatat
     4441 ttttatatat tatataggca tagttatgac aattatttac tgtaatctta tgaagtttat
     4501 tagttttgga gagagtttat atattctttt atttagttct tttatattgt tatgtttttt
     4561 aatatataag tattataaaa atagagaagt atataatctg tttgaaaaag gagtacattc
     4621 tttggaggag tcatttttgt atttaggaag ctcattcttg gggagaaata tatcagttat
     4681 tttaaaacaa caacataaat tgtatcaatc aatgatacaa gagcataaaa agatacatag
     4741 tgaacattta actttcatca accaatggat tcatcagatg aaaacaccaa tatcagttat
     4801 aagccttcag cttcaagatt atgagggaga agaagtaact gaaaatataa gaaaagaaat
     4861 agatagatta aataaagggt tagatatggc tatgcatttt gcaagggcag ataattttca
     4921 gaaagacttt atagttgaaa aagccaaatt aaatgaaatt gtatctagta ttgtaaatga
     4981 agaaaaaagg ttatttataa aaagtggaat gattcctaag attcaagtag acaaatttac
     5041 ttatgtttat acagatgtaa aatggatgaa atttataata ggtcaattaa ttacaaatgg
     5101 agtgaaatat tctaaagatt atagtaacta cctaactata aaatctgaag aaaataataa
     5161 atatgtaatt ttaagtataa tagatgaagg aattggaatt gtttctaaag atttaaaaag
     5221 ggtatttgac ccatttttta caggagaaaa tggtcgtaag tttggagaat ctacaggtat
     5281 gggtctttat ctagtaaaaa aggtatgtga tgatttaggt cataaagtaa gtataaaatc
     5341 agaagtagga aaaggtacag aagtttcaat ctactttaat aaagatgtaa atagtttaat
     5401 aaaggtgtaa attatctgtt acaatagggt ttttagttaa ttgtactttt ttattataca
     5461 atttattaaa tgaaatattc atagttaaat aatcaaaatt taagagagtt tatttgcaaa
     5521 ccttacatag atgtaaggtt tgtgtaatgt ttgcagatag ttaaattttc taatctaaat
     5581 tacaattaat ataagaaata acataagaga aataacataa aaaaagaaat tttgtaaaaa
     5641 aggaaggatg tttattgatg agtttagatg ttatttttat attgaaatca gtcataatag
     5701 ctatagtaga ggggcttaca gaatttattc cagtttcatc tacaggtcat atgattttgg
     5761 ttggtaattt aatagatttt aaggggcaat ttgctgaaat gtttgaggtt gtaatacaac
     5821 ttggggctat attagcagta gtagtacttt attggaaaaa gataaaagat agcgttatag
     5881 aattttttaa atttatattt actggtggaa aagaaggaaa gattggtttt agatttggaa
     5941 tgaatgtaat tataggttgt ataccatttg cgattatagg ggttctattt tacgataata
     6001 taaaatcatt gtttaattta caatctgtaa ttataggatt tatagtgggt gggattttat
     6061 tattagtagt agaaactttg tttagaaaaa agaatcattc cacagataat atagataaaa
     6121 ttactccaat acaagcttta aaggttggga cattacaagt tttgtctgca tggccaggta
     6181 tgtcaaggag tgcatctact attatgggtg gatggatagc aggacttaat tctcctacag
     6241 cagctgagtt ttctttcttt ttagcagtac cagctatggt ggcttcttca ggaaaagatt
     6301 tatttgaatt tgattattca ataatgacac caacattgtg gattgctttg gtagttgggt
     6361 ttatagtagc ttttattgta tcaataatag ttatggaaaa attcgtgaat tttttaaaga
     6421 aaaaaccaat gagagtgttt gctgtataca gaataatcat gggtgtagta cttgcagtat
     6481 tagcttttac taacataatt agtgtataga aaaaatagat ttattatcta taaaaattaa
     6541 actaagataa attataatta acaattatat atatgttatt tcaaaaatta aattaggaag
     6601 gatagttaaa taatgaaaat tttaactgta aataatttaa gtaaagtata tggtaaaaaa
     6661 ataattttca acgcattaaa tgacataaat tttagtatag aagatggaga atttgtagga
     6721 attatgggtc catctggtag tggaaaaact actcttttaa atatgatttc tactattgac
     6781 aagccaacta caggaactat ggaattaaag ggcaagaatc ctttattgtt aagaggtgag
     6841 gaacttgcat tatttagaag aagagagtta ggttttgtat ttcaggattt taatttattg
     6901 gatacattaa ctataggaga aaatatagta ttgccattga cattagataa ggtcagtgta
     6961 aaagagcaag atgagagatt gaatgaagta tctacaatat taggtataaa agatttatta
     7021 ggaaaaagaa cttttgaagt atcaggtggt caagctcaga ggactgctat tgctagagca
     7081 ttgattaaca atccatcaat acttttagca gatgaaccaa caggtaattt agattcaaag
     7141 tcatcaaagg ttgtaatgga gctatttcaa aagataaata aagaaaataa agttactact
     7201 atgatggtaa ctcatgaccc attagcagcg agctactgta gtagaatctt attcataaaa
     7261 gatgggtcta tatataatga aatatataag ggtagtagta gagagcagtt ttatcaagag
     7321 ataatggatg tacttacatt attgggaggc gataactaat gaatataaaa cagtttgcta
     7381 ttaacaatat ttcaagaaat attaaagcgt atttaggata cttagcaagt attgttatat
     7441 catcttcact gctattttct tttattatgt ttacaagtca tccagattta gatgtatctc
     7501 aatttcctga ttatttaaaa gaaggtctca agatgagtaa gataattgca tatctattct
     7561 tattcttctt tgtgttttat tcagttagtg tgtttcttaa aagtagatat aaagaatttg
     7621 gaatacttta tattacaggt atatcaaagc gccaagtaat gaaattaatc tttatagaaa
     7681 atatgataat aaatatagta tcttctgtaa ttggaataat aataggctta atctttgcaa
     7741 agatattttt agtggttatg tctacttttt tagaattatc gccattaaaa ttctatatac
     7801 catttaatgc gatattgtct actttaatct attttatgat tttagctgta ttaacatcaa
     7861 tatttacttc ttttatagtt aaagaaaatc aggtgttgaa gttacttaaa ggtacaaaaa
     7921 ctccaaaacc agagcctaaa acatcactaa tgcttgctat attaagtatt tgtttgttta
     7981 taatagcgta ttataatgct attacctcaa ccgaccaata tacaacatat ctgcgcttag
     8041 ttccagttac atcccttact atagtagcaa cttacttgtt cttttctcaa tttagtgtat
     8101 tttttatgaa gaagctaaaa ctaaacaaga gattttatag aaaaaataca aatatgcttt
     8161 ggatttcgaa cttgatttat aaggtaaagg ataatgctag aatatttttc ttgataacta
     8221 taacttctgc agtagcattt actgctatag gtacagttta ttccttttgg aaagatgtag
     8281 agcgtcaaat taatttaata tatcctaaca caatatatta ttcaacaatg acattgcata
     8341 atgaccctaa aaagcctgat agcaaagaaa aagacaagga aagaatgatg tttatagaaa
     8401 ataatctaaa aaaagagaat gtagactata caaggactaa tggtgaattt aaaactgtat
     8461 ttcccaagaa aagtgatttt aatgtcagaa ttatgaaaga atctaagtac ttagaaatta
     8521 cagaaactat aggggttaag cctataagtt ttgaagataa tgaatgtata tcattattat
     8581 catcaagttt accaggaaat aataacgtca aagaaaatat tattgtaggg aatagaggtt
     8641 taaaggtggc aaaacaagtg gaagaatgtg ttatgccagc atattacaaa aatatgtatg
     8701 tggtaaagga taatttttat gatagtatag aatcaaaatt tatagtggat agatttactg
     8761 catttgaagt agaggattca agtaaaacta tagagatatg cagagaattt gaaaataaat
     8821 ttaataatga gtcagggatg caaccatatt tgtttttctc taaagaatta atgataggaa
     8881 ctgggaaatt aatgtattct acatttatat ttttagcaat atttataggt ttaattttct
     8941 ttgttactac aagtagtttt ttatataata aattttatat ggattgccaa gttgataaga
     9001 aaaagtatga acagttaaat aaattgggta tgacatataa tgagattaaa aaagcttcaa
     9061 caattgagat tggaatagta tttttgtttc cttatgtagt ggctgttata cattcaatat
     9121 ttgcacttac tgcactgaaa aattcttttg atatagaagt agcatcatca gctgttttgg
     9181 taatgggaag cttgttcttg gttcaaatag tttatttttt aattgtaaga aataattatt
     9241 taaaagagat aaggttaaat ttagtcaatt tttagttact attattaaat gataataaaa
     9301 agggtttaga attaattaat attactggaa ttatagatat ttattttttc agtaatattt
     9361 tttattgtat taactattaa aattttgtat aaatataaaa tataatatgg taaatgtcaa
     9421 aattataaaa aaattctact tatataaaat ataaagaggt tatatgtaca tatgtgtaga
     9481 aataaataat aaaaatatca attaatttta ttaggggggt tactcattag taaattagct
     9541 aatagaatga tgatattaat tcaaagcaga ggcaaaatga aatgcaaaga attaccagaa
     9601 gagttggaag taagtgaaag gcaaataaaa agttacaaga tgtatttaga gcaagctggt
     9661 atatttataa attcaacacc tgggatttat ggtggttatg aaataaataa atgtaatagc
     9721 atatcattaa ttaaattatt agatagtgaa gtttcaattt ttatatcaac taagtggtag
     9781 ataagtagaa tattagcaat atcaacgagt atttagaaac ttgttttata ttaataaagc
     9841 agtatataaa attgtagaat caacaatagc atatactaaa acatccacct tatattaact
     9901 aaatcatatc taaataaaat acacttacct acaaacatta taaaatcaat acaaaaatga
     9961 ggtgaaacaa aatttatgat aaagaaatta aacagtaaag acataaataa aatcatggaa
    10021 atatgggaaa aaagtacaat caaagcacat gactttataa gtaaagaata ctggcaaaat
    10081 aactataata ctgttaaaaa cgaatatata cctatatcag atacatttgt atatgatgat
    10141 ggagatgaaa taaaaggatt tataagcata atagataaaa gctttatagg agctttattt
    10201 ataaagccca aataccaaaa tctaggtatc ggaggtaaac ttttagatta tgcaactaaa
    10261 aaatataaaa gtctaagctt agcagtatat aaagataata aaaaagcagt tgtgttttat
    10321 aataaaaaag gttttaatat agtaaaagaa caagtaaatg aagattcagg atttaaagag
    10381 tacataatgg aatatagtaa ataatatgat tacattctat taaaaggata attaatttat
    10441 ttgccatttg attttttaag agtaattttt aaaatagact atatgaagat aaagatattt
    10501 attatagatg taagttaatc agaattgata tagatacaaa agaggaaaat aaaattgtat
    10561 ggtgtatttc agatttaaca aatttactat ttaaagataa taagtttgat ataatattaa
    10621 agatactttc acctataaac tatagggtat ttgaaagaat tttaaataat tatggaatgc
    10681 taataaaggt ttgttaaaat ttaataatta ttagattata gaaaattgcc atgaaattag
    10741 ttcatcaaga actagtttca tagcaatttt aattcttata agtgtattta tttttacaga
    10801 tttaaaaaac ttatacagta tctaataatg taatcttatt actttagcct ataaatattt
    10861 aaatcttaaa atgttctctt tgagataagt ttatttcaga gtcacaattt ccacaacagt
    10921 aagatgttga gacatcttta aatttttcag tattctcatc aaagttcatt tttttctttg
    10981 caataattcc taccttagtt aaattagaac cacaattatt acagttttga attttgcata
    11041 ggttatatag tttatcaagt gtaatatctt ctaataattc atcacaatta caacatctga
    11101 tagaagaaac ttcactacac atttcaatag gttcagcttc tttagaagaa aatttatatg
    11161 ttatgtcatt tgatacttta taacctgtat caaatatatt agaattacaa cttggacata
    11221 agtactttgg aagatatata tctttttttt caaaagtatc actactaata ttacagttta
    11281 attcatctaa aattggtctt tcatctaggt tattaccttt atttaagctt agaagataat
    11341 tataaatttt tttatcttca ttctgctttg atgtatctaa caaatgctcc attatattag
    11401 tgtatttttt gttttttgaa ggcatgttta aatccagata attgttttca atagcaaagc
    11461 atactatatt gaaatagtta tatttaactg caaaaaataa taacatttca tcaaatactt
    11521 tatctattat tttgtcagaa atacttatcc aaaaatctgg ggactctaag taaactttcc
    11581 tactaagttc atctaactct tcatctatat tatttatatt attttcatta actttcatat
    11641 catcacttcc ttttaaatat cttgtgtata aactatttgt tactattttt tatataaaat
    11701 aaaatcttat ataaaaatat atcatattat aatttacaag tatagtctaa atagagctgt
    11761 ttttaagcaa agttttataa atgactatta aaatataaag taacagtata aagtttactt
    11821 ataaattaaa tgtaaaccta aataattata atagttgaca aaaaaacgtc tttattttat
    11881 actaaaacaa agctttaata gaagctttgt atatgtacat ataaactaaa tgaaataaga
    11941 catatgaagg gaattataaa aatgaaaaat actaaagtaa atattcaaga tttaactaaa
    12001 atgtcaatat gtgtagcatt attgtgtata tcatcttaca tatatatacc attgccattt
    12061 actccagcag gagtaacagc acaaacaata atgataaatt taatagcttt aattttaaca
    12121 ccaagacaag catttagtac agttggtgta tatataatga taggtttaat tgggattcca
    12181 gtatttggag gaggtacatc tggtattgga aagttgttaa gcccaacagg tggtttttat
    12241 tttgggtttt tgtttgcagc actaattatt agtttattaa aaggacgaaa taatgatatt
    12301 aagagatata tactaataac aatttttgtt ggaatgccta ttatatattt tatgggaaca
    12361 gtatttatgt gctattttaa tcaaatgaca gtagaagcag cactttttgc agcagtagta
    12421 ccatttttaa ttggagatac aataaagtcg gttattgcat cttttttagg cactaaactg
    12481 aacaatgtac tcagaagaaa tctatgataa atctataata taaggaaggg tgtaatgtat
    12541 ggaggaagtt tttatattag gaggattgag aagtcatata ggtctaaaaa atggaatttt
    12601 tcaatttgtt caacctgaat tactaggagc aagtgtttta aaagatttaa ttaaaaagta
    12661 tgaaattgac aaaattgatg agattatatg tggaaatgca gttgggacag gagggaatat
    12721 agctagatta atgactttaa cagcaggagt gtcaaatgaa gtacctgctt ttactgtgga
    12781 tatgcagtgt gcttctgcta tgatgagtat agacatagct ttttcaaagg ttaaatctgg
    12841 tcagtgtgat ttaattattg caggtggttt tgaaagtagt tctctacaac caatgcgcac
    12901 atatcataag aatgataagc gatatgatac aaataatcca aattatacag ttgctcaatt
    12961 ttctcctgat gataatagcc aaaatagtat gctcgaaggg gcggaaagag tagcagagct
    13021 atatcaaatt gagaaagcag acttggattt ttgggtaaag gaaagtcata aaagagcaaa
    13081 agaagcaaga gaagaaaaaa tacttgagga tattatatct cctataaata atagtaccta
    13141 tgatgaaggt atacgtgata agatgagtca aaggttatta gataggatgc catcaatttt
    13201 aggaaaagaa actattacaa atgcagcaaa ttcatgtctt attaatgatg gagcttcatt
    13261 tattataata tgttctaaga agtatttaga acatgtaaaa aagaagccta aagcaaaaat
    13321 tattaataca tgcacaatag gaacagatgc aaccttaagt ccaacatcag cgatacaagc
    13381 aatggataaa cttttagaga tagaaagtct taattattta gatgtatctg ctgttgaatt
    13441 taatgaagca tttgcagtta tagatgtgtt gtttcaaaga aagtatccag agttaataga
    13501 tagatataat atatttggtg gagctttagc gtatggacat ccatatggtg cttcaggtgc
    13561 aattattgca ttacatcttt taaaagcatt agaaaagact aagggtagat atggaatttg
    13621 ctctatagct gcagctggtg gtctaggttc agctttactg cttgaaaggg tgtagattat
    13681 gaactattat gaacttttaa gaataaaaaa agagagacat aaaaataaaa attttttaat
    13741 tatagatgga gaaaaatata cttatgaaaa tctattgagt tatagtgagg aactaggaaa
    13801 acaaatttct ttaggtgaaa atatcccaat tttaatatat tctaaaaata taatgtttca
    13861 gttgattagt ttttttgcta ttaattattc aaaaaatatt cctattattt gtcattataa
    13921 tctttctaaa aaagtattag atgatatttt attaaaaaat aatatttcaa tcattatatc
    13981 tgatgaatct atggacgtta ttgatttata tgatgataac aataatgaag tagcaaaaaa
    14041 agttaatttt tctattttta atcctaaatt taatatatat atgtatcaat ataagaagct
    14101 tataaattat ttagataaaa gtatttgtat gggagcttta tcttcaggtt ctacaagtgt
    14161 tccaaaggta ttatatagaa catatgagag ttgggctgga ttttttccta tacaaaatgg
    14221 tatttttaat atctctgggg aatcaatctt gtttgttaat ggaacactta gttttacagg
    14281 gaatctaaat tctataatgt cagtattata tgaaggaggt agtattgtaa taagttcagg
    14341 tcttaattgt aaatcatgga taaggacaat aaaacaatat aatgtaacta acatatacct
    14401 tatacctaca aaacttcaac ttttggttaa acacttaaaa gaaccagtac tcaaagttgt
    14461 aagtattttt acagggtctc aattattatt tgaagatact gcaagaaatc taaaaaaata
    14521 tatgccaaag tctgaaatta ttttatacta tggggcaagt gaattaaatt atattacata
    14581 tttatgctat gatgaactaa ttgaaaaacc tctaagtgta ggcagaccat ttccaggaat
    14641 agatatatat attagagaag gaaaaatttt tgtgaataca gaatatgcag tatataatgc
    14701 aaccaaacct tattctgtca atgatattgg atattatgat aatgatggat acttaatatt
    14761 tgaaggaaga agtgatgaca ttataaatat tggaggattt aaagttagtt ctactaaaat
    14821 tgaaaatgaa gttaaaaaaa ttcctcaaat tgaagatgca attgtattgc cgtactcaga
    14881 cactataaga ggaaatcaaa ttgtattatt tgtaataact atagacaaaa ttacgaagaa
    14941 agatttgttg attaaaatga aagataatct aatgaaaaat gaaatcccaa agaaaattat
    15001 ctttttaaat tcatttccat atacctcttc tgaaaagata gatagattag cattattaaa
    15061 aatgttataa gtataatatt tagtaatttt agtgaaccaa tgtattgata aaaacatatt
    15121 gtatatagta aaggaggctt acaatatgtc aaatcaatac gatataactg ttattggggg
    15181 agacctgcga caagtgtaca tggtaaaaaa actaattaat aaagggtatt ctgtagtcac
    15241 ttatgggata tcaaatgaaa ttataaatgg aatcgttgga aaatcaactt cactagctga
    15301 agcactatcc aaaagttcca ttattttatg tccaattcca tttacaaaga atcaagttaa
    15361 tattgaaaat acggatgatt gtcttgatgc tactattgat aacttgctaa ttaatttatc
    15421 tcctaatcaa atattatttg gaggtaacat accaactaaa gtttgtaaat tttgcgagca
    15481 acactctatt cagatttatg attttatgaa aatgaatgat gttgctattt taaatgcagt
    15541 tgctacagct gaaggggcta tagcagaagc tattaaaaga agtataatca atatacatca
    15601 aagtaactgt ttagtattag gttatggaag atgtgcacaa atacttgcaa aaaaattata
    15661 cgctttggat gcaaatgtat gtgttggcgc aagaaataat gatgcaagaa gtacggctaa
    15721 tgcatttgga tattccagta tttctttaag tcaacttgat gaaaaacttt tacaatttga
    15781 ttatattttt aacaccatac cagagtgtat tttaacgaaa gaaaggttag aaaaagtatc
    15841 acaagaagta actattatag atatagcttc ttctcctgga ggagtagatt attctgttgt
    15901 taaagaagca gggattaatg cgactctttg ccttgggctt cctggtaaat attcaccaaa
    15961 gacatctggt gaaattcttg ttaacgctat agaaaatatt ataaatgaaa gaagggatta
    16021 gaaatgagac ttgaaggact tacaattgga gtaggattta ctggttcgtt ttgtacttat
    16081 gataaaatat ttatagagtt agagaatttg gttaaagaag gagctaatgt acacactata
    16141 ttttcagatg tatcacaaaa tatcgattgt agatttggaa attctgaaga gtttatgaaa
    16201 aaagcatatg aacttacagg aaataaacct atagttacga ttgaagaggc agagccattt
    16261 ggacctaaag gaattgctga tattataata atagctcctt gtactggaaa tactgctgca
    16321 aaattagcaa atggtattac agattcacca gtattaatgg cagcaaaagg tcatcttcgt
    16381 aatgataaac cactagtaat atcaatatca acgaatgatg ctctaagctt taatttcaaa
    16441 aatattggca ttctccttaa ttctaaaaat atatattttg taccttttgg tcaagataat
    16501 tgcaaagcaa agcctaattc tatgattgca catactgagc taataattcc aactatagaa
    16561 cttgctctag agaacaaaca gctacagcct gttataaaaa gtccacatca atagaattgg
    16621 ttcttataat attatgtatt agatacaata ctagcaaaga ggctgtctca aaatagagag
    16681 aagcctcttt ttcttgttga aatgatgaaa atatatttaa tttcatacaa aaaaatgcct
    16741 catggactaa aaagtctatt ttgagctaat ctccgtaatt tttggtatat taaaattatt
    16801 tacttaatcc aatttttaaa ttagaattta tatcgttttg actcttcaaa tatcaatcta
    16861 actgttgttg atacaaaaga agaggacata attaaaacaa ataccgatag tcctctaata
    16921 aacaaattat ctacataata agttactatt ccaatacctc caatcgttaa aattacactt
    16981 ataatcaaag aaaaaatgct aattgttttt aattttttca tgcttatcct ccttcttata
    17041 aacttcaaat ttatctatat aatat
//
LOCUS       DAEQAF010000081        16619 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.084, whole genome shotgun sequence.
ACCESSION   DAEQAF010000081 DAEQAF010000000
VERSION     DAEQAF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16619
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.084"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..639
                     /gene="tuf"
                     /locus_tag="KRN00_002793"
     CDS             <1..639
                     /gene="tuf"
                     /locus_tag="KRN00_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBH1828649.1"
                     /translation="EWGDKIVELFEQIDEYIPAPERDTDKPFLMPVEDVFSITGRGTV
                     ATGRVERGVLKVQDEVELVGLTEAPRKVVVTGVEMFRKLLDQAQAGDNIGALLRGVQR
                     NEIERGQVLAKTGSVKAHTKFTAEVYVLKKEEGGRHTPFFDGYRPQFYFRTTDVTGAC
                     KLPEGIEMVMPGDNVTMEVDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
     gene            889..1038
                     /gene="rpmG"
                     /locus_tag="KRN00_002794"
     CDS             889..1038
                     /gene="rpmG"
                     /locus_tag="KRN00_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBH1828650.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            1064..1285
                     /gene="secE"
                     /locus_tag="KRN00_002795"
     CDS             1064..1285
                     /gene="secE"
                     /locus_tag="KRN00_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBH1828651.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            1305..1847
                     /gene="nusG"
                     /locus_tag="KRN00_002796"
     CDS             1305..1847
                     /gene="nusG"
                     /locus_tag="KRN00_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBH1828652.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1886..2311
                     /gene="rplK"
                     /locus_tag="KRN00_002797"
     CDS             1886..2311
                     /gene="rplK"
                     /locus_tag="KRN00_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBH1828653.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            2381..3079
                     /gene="rplA"
                     /locus_tag="KRN00_002798"
     CDS             2381..3079
                     /gene="rplA"
                     /locus_tag="KRN00_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBH1828654.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    3131..3259
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            3302..3808
                     /locus_tag="KRN00_002799"
     CDS             3302..3808
                     /locus_tag="KRN00_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBH1828655.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3866..4231
                     /gene="rplL"
                     /locus_tag="KRN00_002800"
     CDS             3866..4231
                     /gene="rplL"
                     /locus_tag="KRN00_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBH1828656.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4623..5411
                     /locus_tag="KRN00_002801"
     CDS             4623..5411
                     /locus_tag="KRN00_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBH1828657.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5882..9598
                     /gene="rpoB"
                     /locus_tag="KRN00_002802"
     CDS             5882..9598
                     /gene="rpoB"
                     /locus_tag="KRN00_002802"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBH1828658.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9640..13125
                     /gene="rpoC"
                     /locus_tag="KRN00_002803"
     CDS             9640..13125
                     /gene="rpoC"
                     /locus_tag="KRN00_002803"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBH1828659.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            13414..13836
                     /gene="rpsL"
                     /locus_tag="KRN00_002804"
     CDS             13414..13836
                     /gene="rpsL"
                     /locus_tag="KRN00_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBH1828660.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13960..14430
                     /gene="rpsG"
                     /locus_tag="KRN00_002805"
     CDS             13960..14430
                     /gene="rpsG"
                     /locus_tag="KRN00_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBH1828661.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14479..16545
                     /gene="fusA"
                     /locus_tag="KRN00_002806"
     CDS             14479..16545
                     /gene="fusA"
                     /locus_tag="KRN00_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH1828662.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6525 a         2066 c         3409 g         4619 t
ORIGIN      
        1 gagtggggag ataagatagt agaattattc gagcaaatag atgagtatat accagctcca
       61 gagagagata cagataaacc attcttaatg ccagtagagg acgtattctc aatcacagga
      121 agaggaacag ttgcaacagg aagagtggaa agaggagtac taaaagtaca agacgaagta
      181 gaattagtag gattaacaga agcaccaaga aaagtagtag taacaggagt agagatgttc
      241 agaaaattat tagaccaagc acaagcaggt gataatatag gagcattatt aagaggagta
      301 caaagaaacg agatagaaag aggacaagta ctagcaaaga ctggatcagt aaaggcacac
      361 acaaagttta cagcagaagt atatgtactt aaaaaagaag aaggtggaag acatacacca
      421 ttctttgatg gatatagacc acaattctat ttcagaacaa cagacgtaac aggagcttgt
      481 aagttaccag aaggaataga gatggtaatg cctggagata acgtaacaat ggaagtagac
      541 ttaataaact caatagttgt agaagaggga ttaagattct caataagaga aggtggaaga
      601 acagtagctt caggagttgt tgctacaata atagagtaat tctttactaa actgatggat
      661 taaaaggaat aacaaaaaga ggggttatgc tcctcttttt ttaacataga aatacaaaaa
      721 cattgacaca gcataggatt ttgtgataac ttatacaagg taatgattat aggaagttaa
      781 taatatcttg aatactgtag atttttaata aatacatatt ttaaagatat tatattcaca
      841 tatattaaca atatatatta ttgtattaca aagttggagg tgtatcagat gagagttaaa
      901 gtaactttag catgtacaga gtgtaagcaa agaaactaca acactactaa gaataagaaa
      961 aataatccag acagaataga attacaaaaa tattgtagat tctgtaaaaa gcatacaact
     1021 cataaagaaa caaaatagtt ttttataagg atgtgagtat ggaatggctg cccaaaaaaa
     1081 tgacggtgca aaaactaaaa aaaggtttag tttgtttgga tacttaaaag aaactaaaca
     1141 agaattaaaa agagttacat ggccgacaaa aaaggaactg tttaaaaaca caagtatagt
     1201 tttaactgta gttatttcat gcactatatt agtatggggt atagacacta tattatctgg
     1261 tgcactagcg ttattactaa aatagacgaa aagaggtaag ttaaatgtca gaattacaag
     1321 aagcaagttg gtatgtagtt catacctatt cgggacatga aaataaagtt aaagctacaa
     1381 ttgagaaagc agttaaaaca agaggtatgg aagactgcat aagacaagta gttgttccaa
     1441 cagaagaagt agtggaaact actaaaactg gaaaagaaaa aactagacaa cgtaaagttt
     1501 atccaagtta tgttttggtt aaaatgataa taactgatga atcttggtat gtagtaagaa
     1561 atactaaggg agttacaggt ttcgttggac ctggttcaaa accagtgcca ttaagtgaag
     1621 acgaagtcaa agctatgggg atagacacaa cagaccctaa agtagtaaat agcgatattg
     1681 attttgaaat aggagataca gtaaaagtat ctcaaggacc atttagtgga caaataggta
     1741 acatagaaga aattgactta gaaaatagag aagtcaaagt atgcataaat gcatttggta
     1801 aaaggactct atttgtaata gagcttgaag gtatagaaaa aatctaatac tatattatag
     1861 aaaaatctga ggaggtgcgc tcaaaatggc taaaaaagtt ataggtcaaa taaaattaca
     1921 aatacctgca ggaaaggcta ctccagcgcc accagttgga ccagcattag gacaacatgg
     1981 tgttaatata atgggattca caaaagaatt taatgctaaa actgcagatc aagctggaat
     2041 gataatacca gttgttataa ctgtatatca agatagatca ttcagtttta taacaaaaac
     2101 tccaccagct gcagttttaa ttaaaaaagc attaaactta aaatcaggtt ctggagaacc
     2161 aaacaagaaa aaagttgcta aaatgacttc agctcaagta agagaaatag ctgaattaaa
     2221 gatgcctgac ttaaatgctg catcagtaga agctgctatg agtatgatag ctggtactgc
     2281 tagaagcatg ggtgttgtaa tcgaagacta attaaaagat acactttttt tataaagtgg
     2341 gaggctagaa gccgaaatta accacgagga ggaaaataaa atggctaaaa aaggtaaaag
     2401 atatgcaggt gcattacaaa aagtagatag aactaaattt tatgatgcat cagaagcatt
     2461 aacattagtt tcagatatag ctggagctaa atttgatgag acagtagaag cacacattaa
     2521 attaggtgtt gactcaagac atgctgacca acaagtaaga ggtgcagttg tattacctca
     2581 tggaactggt aaaacaaaaa gagttttagt ttttgctaaa ggtgaaaaag ctaaagaagc
     2641 tgaacaagct ggtgctgact ttgtaggagc tgaagaatta gttcaaaaaa tacaaggtga
     2701 aaactggttt gactttgata tagtagttgc tactccagat atgatgggtg tagtaggtag
     2761 attaggtaga gtattaggac ctaaaggttt aatgccaaac cctaaatcag gaacagttac
     2821 atttgatgta gctaaagcta tagatgaaat aaaagctggt aaagttgaat acagattaga
     2881 caaaactaac ataatacacg ttccagtagg aaaagtatca tttggtggag aaaaattaac
     2941 tgaaaacttt actgcattaa tggatgctat aataaaagct aaaccagctg ctgctaaagg
     3001 acaatattta agaagtataa cagtagcttc ttcaatggga cctggagtta aaataaaccc
     3061 agcaagaaca gctgaataat aaaactgttg acacaggttg acaaaaatgt tattatatca
     3121 cttgtcaatg taaaaaagaa tagatttgcc gtagatagtg ggtgcgagag cttaatatcc
     3181 cgccgaggtt ttagataaat tgagattact aaagcttttg atgtctactt ttggcaacaa
     3241 aagcttttta taatgttgcg gtaaatacta agcctatttg gtgaaggagg tgcacatcta
     3301 tatgagaaaa gctatagaaa ttaaatcaga agttgtttct gagatagttg aaaagttaca
     3361 aaaatcttct gctgctgttg ttgtagatta caaaggatta acagttgaag aagtaactga
     3421 gttaagaaaa caaatgagag aagctggtgt agattacaaa gtatacaaaa atactttagt
     3481 tagaagagca gctaaagaag ttggtataga gcaatttaat gatgaattat tagttggaac
     3541 taatgccata gcatttggat atgatgatcc agttgctcca gctagaatat taaaaggatt
     3601 catggattct catccaaaaa tgaaattaaa gatgggtatt gtggaaggtg cattctatga
     3661 tgaatctaag attgttgaaa tggctaacat accatcaaga gaagttctta tcgctaaatt
     3721 acttggtagc ttaaaagctc cagtatcaaa cttcgcatac ttaatagatg caatagcgaa
     3781 aaaggcagaa ggtcaagaag aagcttaatt gcttaactaa aaaattataa atattaattt
     3841 gaaataaaat tcggaggtgc taaaaatgac aatagaacaa atattagaag ctatagaaaa
     3901 tatgaaagtt ttagaattaa atgaattagt taaagctgct gaagaaaaat tcggtgtatc
     3961 agcttcagct ccagtaatgg tagctggtgc agctgctggt ggaccagctg ctgaagaaaa
     4021 aactgagttt gatgtagtat taactgacgt tggttcttca aaagttggag ttataaaagc
     4081 agttagagaa ataacaggat taggattaaa agaagctaaa gaagtagttg acaatgctcc
     4141 taagacagtt aaagaaggag cttctaaaga agaagctgat caaataaaag agaaattaga
     4201 agctgctgga gctaaagtag aagttaagta gtttctttaa aaagataccc attgggtatc
     4261 tttttttatt tataaaaaac tataaagaaa gtatttggaa ttataaagaa agtattttta
     4321 taaaataaaa aaaatttata taatagtact aaattaaggg tatcatatat gatgtaatgg
     4381 tattttaatt taacattatt atcaaattaa aatataaaca attgttgtaa tgtctatata
     4441 taaagtatat aattaaacta aaatgtaaaa ttttacattt tagtttaaaa aaatacacga
     4501 gtgttttgta aataaaatgt aataaataat taattaacaa atataaattt taaaataagt
     4561 tagatattta gaaaaatcga aatttgtagg atttaaagga catattcaag gaggagttaa
     4621 taatggaaaa attacaagga aaaattgcag tagttactgc agcaacaaaa ggtattggat
     4681 tagcatcagc agagatatta gcaaaaaatg gagcaactgt gtacttagca gctcgttcag
     4741 aagaattagc taatgaagtt ataaataaaa taagtgcaga aggtggttgt gctaagtttg
     4801 tttactttaa tgctcgtgaa gaagagacct ttacctcaat gatagaagag gtagttaaaa
     4861 aagaaggtaa gatagatata cttgtaaaca attttggttc aacaaaccct tctcttgaca
     4921 aagaccttgt aactggggat acagataatt tctttgacac agtaaatact aatttaaaaa
     4981 gtgtgtattt accatgtaaa gcagcaattc ctcatatgat aaagaatgga aaaggaagta
     5041 tagtaaatat atcaagtata ggttcagtat tacctgattt atctagaata gcttactgtg
     5101 tatcaaaagc agcaatcaac tcattaactc aaaacatagc tacacaatat gctaaagaca
     5161 atgttagatg taatgctgta cttccagggc ttattgcaac taaagcagca ttagacaata
     5221 tgtctccaga gttcataaaa gaatttttaa agcatgttcc tttaaatcgt ataggggaac
     5281 cagatgatat agcaaaagct gttctattct atgctagtga tgactcatca tttataacag
     5341 gggatttact tgaagttgca ggaggatttg gtttacctac tccacaattt gcagataata
     5401 tattaggata attaaattac taatatgcaa tgaaagctta tgcattagtt atagtagaaa
     5461 tgatattttt ataaaggcca tagatataat ttatattgga aaggtttgag gttcaaaatt
     5521 ccaagttaaa tttatttatg gtctttattt tgtatatttt aataaattgt atatatttgt
     5581 ataaatgtaa ttatttacaa tcattttaat atggaattat aattaaatag gggggatggt
     5641 acttgtataa aattttttat agaaagttag acctataaat gaaaaatatg gattttatat
     5701 tggaaaattg tacataatac ataatatatg cttaaaataa tttacaaaaa atcaaaaata
     5761 atgcatagtt tacatataag ataaaaaata tattgaaaaa tacttgacat tatgctaaaa
     5821 ttattagatg cgttagaatg aactattgtt ttatttttaa ttattgagag gtgaaaagtg
     5881 aatgccacat cctgtcacga taggtaaaag aactagaatg agcttttcta aaattaagga
     5941 aatagctgat gtgccaaatc ttatagaaat tcaagtagat tcctatgagt ggtttttaaa
     6001 agaaggttta aaagaagtgt ttgatgatat ttcaccaata gaagattata ctggtaatct
     6061 tatattggaa tttgtcgact attctctaga tgataaacca aagtacgata tagaagagtg
     6121 taaagagaga gatgctacat attgtgcacc tctaaaggtt aaggtaagac ttataaataa
     6181 agaaacaggt gagataaaag aacaagaagt gtttatgggt gacttccctt taatgacaga
     6241 aagaggaact ttcgttataa atggagcaga aagagttata gtaagtcaat tagttagatc
     6301 tcctggtgtt tactatgcgg aagaaagaga taaaacaggt aagagattga tttcatctac
     6361 tgtaattcct aatagaggag catggttaga atatgaaaca gattctaatg atgtaatatc
     6421 tgtaagagtt gatagaacaa gaaaacaacc agttacagtt ttacttagag ctttaggaat
     6481 aggaacagat gcagagataa ttgacctttt aggagaagat gagagattat ctgctacatt
     6541 agaaaaagat aatactaaga cagtagaaga aggtcttgta gagatataca aaaaattaag
     6601 accaggtgaa cctcctactg tagaaagtgc atcatcttta ttaaatgctt tattctttga
     6661 cccaaaaaga tatgacctag caaaagttgg tagatataaa ttcaataaga aacttgcttt
     6721 atgttataga ataatgaata aaatttcagc agaagacata ataaatccag aaactggaga
     6781 agtatttgta aaagctggag aaaaaataag ctatgatttg gctaaagcca tacaaaatgc
     6841 aggtataaat gtagtaaatc tactaatgga tgatgataaa aaagttagag ttataggaaa
     6901 taattttgtg gatattaagt ctcacattga ttttgacata gatgatttaa acataaaaga
     6961 aaaagtacat tatccaactt taaaagaaat tttagatgga tatagtgatg aagaagaaat
     7021 aaaagaggct ataaaatcaa gaattaaaga acttatacca aaacatatat tattagatga
     7081 tataatagct tcaataagtt atgagttcaa tatattctat aatataggaa atattgatga
     7141 tatagatcac ctaggaaaca gaagaataag atctgtaggt gaattgttac aaaatcaagt
     7201 tagaattggt ctttcaagaa tggaaagagt tataaaagaa agaatgacgg ttcaagatat
     7261 ggaagctata acgcctcaag cgttagttaa cataagacca gtttcagctg caataaaaga
     7321 attttttggt agttctcagt tatctcagtt catggatcaa acaaatcctc tatctgagtt
     7381 aacgcataag agaagattat cagcccttgg gcctggaggt ctttcaagag aaagagctgg
     7441 attcgaagtg cgtgacgttc accattcaca ctatggtaga atgtgtccaa tagagactcc
     7501 agagggacca aatatcggtc ttataaactc tctaggaact tatgcaaaaa taaatgaatt
     7561 tggatttata gaatcaccat atagaaaatt tgataaagaa acatcaacag ttactgatga
     7621 aatacattat ttaactgctg acgaagaaga tttattcgta agagctcagg caaatgagcc
     7681 attaacagaa gatggtaaat tcgtaaacca tagagttgtt tgtagaactg taaatggtgc
     7741 tgttgaaatg gttcctgaaa gtagagtaga ttacatggat atatctccta agcaggttgt
     7801 atctgttgcc actgctatga tacctttctt agaaaatgat gatgccaacc gtgcccttat
     7861 gggagcgaac atgcagcgtc aggcagtgcc tctagttaga agagaagcac caattatagg
     7921 aactggtata gaatacagag cagcaaaaga ctctggagca gttgttgttg ctagaaattc
     7981 tggtatagca gaaagagtaa cagcagatga aataattata aaaagagaag atggaaacag
     8041 agatagatat aatctactta agtttaaacg ttcaaactca ggtacttgta taaatcaaac
     8101 acctataata aataagggtg accagataat aaaaggtgat gttatagcag atggtccagc
     8161 aactgattta ggagaagttg cacttggaag aaactgtctt atagcattca tgacttggga
     8221 aggttataac tacgaggatg ctatattaat aaatgaaaga ttagttaaag aagatagatt
     8281 atcaacaatt catatagaag aatatgaatg tgaagctaga gatacaaaac tagggccaga
     8341 ggaaataact agagatatac ctaatgttgg agatagtgca attaagaact tagatgacag
     8401 aggtataata agaataggtg cagaagtaga ctcaggtgat atattagttg gtaaagtaac
     8461 tccaaaagga gaaactgaac ttactgctga ggaaagatta cttcgtgcaa tatttggaga
     8521 aaaggctaga gaagttagag atacttcact taaagtgcct catggtgaat ctggtataat
     8581 agttgatgta aaagtattta ctagagaaaa tggagatgat ttatctccag gagtaaatga
     8641 attagtaaga tgctatatag ctaaaaagag aaaaataaaa gttggagata aaatggctgg
     8701 tcgtcatggt aataaagggg ttatctcaag agtattacct gaagaagata tgccattcat
     8761 ggaaaatgga acaccactag acataatact taacccacaa ggtataccat cacgtatgaa
     8821 cattggtcag gttttagaag ttcatttagg acttgctgct aagacattag gatggtatgt
     8881 agcaacatca gtattcgatg gtgctaatga gtatgacata atggatgctc ttgaagaagc
     8941 tgggtatcct agagatggta aattaacttt atatgatggt agaacaggtg agtcttttga
     9001 caacagaata actgttggat atatgtacta cttgaaacta catcacttag tagatgaaaa
     9061 actacatgca agaagtactg gaccatactc attagttact caacagccac taggtggtaa
     9121 agcacaattt ggtggacaaa gatttggaga gatggaggtt tgggctctgg aagcatatgg
     9181 agctgctcac atacttcaag aaatacttac tgttaagtct gatgacgttg taggtcgtgt
     9241 tagaacatat gaagctatag ttaaaggtga aaatatacct gaaccaggaa tcccagaatc
     9301 atttaaggtt cttataaaag aacttcaaag tttatgctta gatgtaaaag tattgacaga
     9361 tgaagaccaa gaaatagaag taagagaatc tgtggatgaa gatgatacaa taggtgaatt
     9421 tgagctagat gttgtaaatc atatgggaga agttgaagaa agtaatataa tagaagaaat
     9481 tgaagatgat tttgcagaaa atgcagaaga tgaggatata gagaatttag aagaattcac
     9541 tgaagatgat ttatttgaag aagaaataga ttttgatagt gatgactttg atatgtaaat
     9601 ttaattaatg taaatctcaa atagaaggga gagaactcct tgtttgaatt aaacaatttc
     9661 gagtcgataa aaatagcatt ggcttctcca gaaaaaataa gacaatggtc taggggagaa
     9721 gttaaaaagc cagaaactat aaattaccgt actttaaaac cagaaaaaga tggtcttttc
     9781 tgtgaaagaa tatttggacc acaaaaagac tgggagtgcc actgtggtaa atatagaaga
     9841 gttagatata aaggtgtagt ttgtgataga tgtggagtag aagtaactaa atcaaaagta
     9901 agaagagaga gaatgggaca tatagagcta gctgctccta tgtctcacat ctggtacttc
     9961 aaaggtatac caagtagaat gggactttta cttgatatgt caccaagatc gttagaaaaa
    10021 atattatact ttgcctcata tgtggtagtt gatccaggag agactggatt aaacgaaaaa
    10081 caattgctta cagaaaaaga atacagaact gctcttgaaa agtatggata tacttttact
    10141 gtaggaatgg gtgctgaagc tgtaaagaca ttactacaaa atatagattt agagcaacaa
    10201 agtaaagacc taagagcgga gttaaaagat agtacagggc aaaagaaagt tagaacaata
    10261 agaagattag aagttgtaga ggcatttaaa aagtctggaa ataaaccaga atggatgatt
    10321 ttagatgcaa taccagtaat accaccagat ttaagaccaa tggtacaact tgatggtgga
    10381 agatttgcga cttcagacct aaatgattta tatagaagag ttataaatag aaacaataga
    10441 cttaaaagat tattagagct tggagctcca gatataattg taagaaatga aaaaagaatg
    10501 cttcaagaag ctgttgatgc attgatagat aatggtagaa gaggtagacc tgtaacagga
    10561 cctggaaata gaccacttaa atctttatca gatatgttaa aaggtaagca aggtcgtttc
    10621 cgtcaaaact tacttggtaa gcgtgttgac tactcaggac gttctgttat agttgttgga
    10681 ccagaactta aattttatca atgtggactt ccaaagaaga tggcattaga attattcaag
    10741 ccatttgtta tggataaatt agttaaagaa ggttatgcac ataatataaa aagtgcgaaa
    10801 tctatagtag aaaaagttaa gccagaagtt tgggatgttt tagaagatgt tataaaaagt
    10861 catccagttc ttcttaaccg tgcaccgact ctacatagat taggtataca agcatttgaa
    10921 ccaatcttag ttgaaggtaa ggctataaaa ctacatcctc ttgtatgtac agcttataat
    10981 gcagactttg atggtgacca aatggcagtc catgtacctt tatcagtaga agcacaagca
    11041 gaagcaagat tcttaatgct ttctgtaaat aatatacttg ctcctaaaga tggttcacct
    11101 ataactactc catctcagga tatggtttta ggttgctatt atctaacaat agaagcccaa
    11161 gatggagcta aaggaacagg tatggtattt aaagacttta atgaactatt acttgcttat
    11221 tacaataaat cagttcatct acatgcatta gtgaaactga aggtaacact tgaagatgga
    11281 agaagttcat tggttgaaag tactgttggt agatttatat ttaatgaaaa tatacctcaa
    11341 gacttaggtt ttgtagatag aaaagaaaat ccatttgcac ttgaagttga tttcttagca
    11401 gataaaaaat ctcttggtaa aataatagat aaatgcttta gaaaacacgg aaatacagaa
    11461 acagctgaat tactagatta tataaaagct ctaggattta aatattctac attaggtggt
    11521 ataacagttg ctgttgatga tatgagtgtc ccagaagaaa agaaagtatt tatagctgag
    11581 gcagaagcta aagttgataa gtatgaaaaa gcatacagaa gaggtctaat ctctgatgaa
    11641 gaaagatatg aaaaagttat agagacatgg acagaaacaa ctgataaagt tactgatgct
    11701 cttatgggtg gactagatag attaaataat atatatataa tggcacattc aggagccaga
    11761 ggttctaaaa accaaattag acagctggca ggtatgcgtg gtcttatggc aaatgcatct
    11821 ggtaaaacag ttgagatacc agttaaatct aatttccgtg aaggtttatc agtactagaa
    11881 tactttacat cttcacatgg tgccagaaaa ggtcttgccg atacagctat acgtacagct
    11941 gaatctggat atttaacaag aagacttgtt gatgtaagtc aagatgttat tgtaagggaa
    12001 atagattgtg gaacagaaga tactacagag atttatgcta taaaagaagg aaatgaagtt
    12061 atagaagaga tatatgatag aattgtagga agatatacta tagaccctat attaaatcct
    12121 gaaactggag aagttatagt tgaggctgat tcaatgatac aagaagatga agcagaaact
    12181 atagtagctt taggaattga aaaaattagg ataagaacag ttcttaactg taaaactaat
    12241 catggagttt gttctaagtg ttatggtaga aacttggcaa caggaaaaga agttaatata
    12301 ggtgaagcag ttggtataat agcagctcaa tctatcggtg agccgggtac tcagcttaca
    12361 atgcgtacat tccatactgg aggagttgca ggagctgata taactcaagg tctaccaagg
    12421 gttgaagaat tatttgaagc tagaaaacca aaaggattag ctgtaataac tgaagtatct
    12481 ggtagagttg aaattgatga aacaggaaag agaaaagaag taaatgtaat accagaagaa
    12541 ggcgagactc aaacatatgt aattccatat ggttctagat taaaagttaa gcaaggtcaa
    12601 atgctagagg ctggagaccc tctaacacaa ggatttataa atcctcatga tatagtaaga
    12661 gtaaatggtg ttaagggagt tcaagaatat atagttaaag aagttcaaag agtgtataga
    12721 cttcaagggg ttgatgttaa tgataagcat atagaagtta tagtaagaca aatgctatct
    12781 aaagtaaaag ttgaagaccc aggagataca gatttattgc caggtggata tgaagatgta
    12841 ttaacattca atgaatgtaa taaagatgct atagataaag gtctaagacc agcagttgct
    12901 aaaagagttt tacttggtat aactaaagca tctcttgcaa ctgattcatt cttatcagca
    12961 gcttctttcc aagaaacaac aagagtatta acagaggcag caataaaagg taaagaagac
    13021 cacttaatag gacttaaaga aaatgttata ttaggtaagt taataccagc aggaacagga
    13081 atgaagaaat atagaaatat agctgttgaa aaaattgaag attaatagca tatagagtaa
    13141 agaaatcttg acaaccatta tttgtggtgt taaaatagta aagtgtgttg tttaaaagta
    13201 cactaagggc ttgaacaagt tcttagtgac ttttagatgg caataaatga gaactaaaaa
    13261 gcatcaagct agaaaagtgc taatatcaca tatttatgtg ttatagacat taaattgtaa
    13321 gtaacgaatg ttacaatcag tcagtatgaa tattcatatt gatgtagttg gcggtcactg
    13381 ataagatcga aaatttggaa ggaggtgcag atgatgccaa caattaacca attagttcgt
    13441 aaaagtagaa aagcgctaga gaagaaatct actgctccag cattacaaaa aggttacaac
    13501 tctttaaata agaaagtaac tgacgctagt gccccacaaa aaagaggggt ttgtacttca
    13561 gtaaaaacag ttactcctaa gaagcctaac tcagctttaa gaaaagttgc cagagttaga
    13621 ttaactaatg gtatagaagt ttctgcttat ataccaggag aaggacacaa cttacaagag
    13681 catagtgttg ttcttataag aggaggaaga gtaaaagacc ttccaggggt tagataccat
    13741 atactaagag gtactctaga tacagcaggt gttgataaga gaagacaatc aagatctaaa
    13801 tacggtgcga agagacctaa agaagctaaa aagtaaaaac aattaatgat tgattatagt
    13861 tcggtgcttt aaatatatat atatttacgg catcacggca ttaaatgatt tatgtcgagt
    13921 acctatgatt taagttaaat aattaaggag ggaagcgaaa tgccaagaaa aggtaatatt
    13981 ccaaaaagag aagttttacc agatcctatg tatgggagta aggtagttac taaattaata
    14041 aataatctaa tggtagacgg aaaaaaagga aagtctcaaa gaatagttta tgatgctttc
    14101 gcaattgttg ctgaaaagac aggagaagaa gctttagaag tatttaataa agcaatggat
    14161 aatataatgc ctgttttaga agtaaaagca agaagagttg gtggggcaaa ctatcaagtg
    14221 ccaatcgaag ttagacctga aagaagacaa acattaggtt taagatggct agtaaaatat
    14281 actagagctc gtggagaaaa aggaatggtt gaaaagctag ctaaagagat aatggatgca
    14341 gctaacaaca ctggagcttc agttaagaaa aaagaagata ctcataaaat ggcagaagct
    14401 aataaagcat ttgctcatta cagatggtag gatatataga tatcttataa aattgaggat
    14461 atcataagga ggataaccat ggctagaaag tttcctttgg aaagaactag gaatatagga
    14521 atcatggctc atatagatgc aggaaaaact actactacag aaagaatcct gttttatact
    14581 gggcaaactc ataaaatagg agaaactcat gaaggagctt ctcaaatgga ctggatggag
    14641 caagaaaagg aaagaggtat aacaataact tctgccgcta ctactgcttc atggaaagac
    14701 catagaataa acataataga tactcctgga cacgtggact tcacagttga ggttgaaaga
    14761 tctctaagag ttcttgacgg ttcagttgct gtattctgtg caaaaggtgg ggttgagcct
    14821 caatcagaaa atgtatggag acaagctgaa acttatggag tacctagaat agcttttgta
    14881 aataaaatgg atatattagg tgcagatttc tacaatgttg taagcatgat gaaatctaga
    14941 ttaaattcta atgcagttcc tatgcaatta ccaataggta aagaagattc atttataggt
    15001 ataatagact tattaaaaat ggatgctgtt atatataaag acgacctagg ggttgaaatg
    15061 gaagaaacag atataccaga agatatgaaa gaattagctg ctgagtggag agaaaaatta
    15121 gttgaatcag tagctgaaac tgatgaagaa ttaatgatga aataccttga aggtgaagaa
    15181 cttactatag atgaattaaa agttgctata agaaaagcta ctatagcttg tgaaatgaac
    15241 ccagttttct gtggtacagc ttatagaaac aaaggtgttc agttagtaat agatgcagtt
    15301 ttagattact taccagcgcc aactgatata ccagctataa aaggtatatt agcagatgga
    15361 gaagaagctg aaagacattc ttctgatgaa gagccattct ctgcattagc attcaaaata
    15421 atgactgacc cattcgttgg aaaactagcg ttcttcagag tttattctgg aacattagaa
    15481 tcaggttctt atgttttaaa tgcaactaag aataagagag aaagaattgg tcgtatatta
    15541 caaatgcatg ctaatacaag agaagaaata actaaagtgt atgctggaga tatagcagca
    15601 gcagtaggat taaaagatac tactactgga gacacattat gtgaccctgc taatccaata
    15661 atacttgaat ctatggaatt ccctgagcca gttatatctg ttgctataga accaagttct
    15721 aaagcagctc aagaaaaaat gggtatagct cttcaaaaat tagctgaaga agacccaact
    15781 ttcacagtta agactgacca agaaacagga caaactataa tatctggtat gggtgaatta
    15841 cacttagaga taatagtaga tagattatta agagaattta aagtagaagc taaagttggt
    15901 gcaccacaag ttgcatatag agagactata actcaaccag ttgatgttga atacaagtac
    15961 tctaagcaat caggtggtag aggacaatac ggtcacgtta agattagagt tgctcctcaa
    16021 gagccaggtg aaggatacaa attcacaaac aaaactgttg gtggatcagt accaaaagaa
    16081 tatgttggtc cagttgacat gggtatacaa ggagctatgc aatctggtat agttgctgga
    16141 tatccagttg tagacgttgc tgttgagtta tatgatggtt cttaccatga ggttgactct
    16201 tctgagatgg cgtttaagat ggctggttca atggcattca aagatgctat gaagaaaggt
    16261 aatgcagttc ttttagagcc ttacttcaaa gtagaagttg ttactccaga agattacatg
    16321 ggagatgtta tgggtgactt aaactcaaga agaggattaa tccaaggtat ggaagctaga
    16381 agtggtgcac aagttataaa tgcattcgtt ccactttcag aaatgtttgg atactcaaca
    16441 gacctaagat cttcaactca aggtcgtgca acttacacaa tgatattcga tcactatgag
    16501 caagttccag cttcagttgc taagaaaata gctgaaggaa aataatttaa aaataattaa
    16561 taatataaat ataaaaaata atcagctaga tgagagatat ctctcatcta gcacaagat
//
LOCUS       DAEQAF010000082        16603 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.085, whole genome shotgun sequence.
ACCESSION   DAEQAF010000082 DAEQAF010000000
VERSION     DAEQAF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16603
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.085"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            151..819
                     /locus_tag="KRN00_002807"
     CDS             151..819
                     /locus_tag="KRN00_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828663.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            821..1306
                     /locus_tag="KRN00_002808"
     CDS             821..1306
                     /locus_tag="KRN00_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBH1828664.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            1367..2488
                     /locus_tag="KRN00_002809"
     CDS             1367..2488
                     /locus_tag="KRN00_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBH1828665.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            2769..3959
                     /locus_tag="KRN00_002810"
     CDS             2769..3959
                     /locus_tag="KRN00_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1828666.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIVNNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     misc_binding    4093..4348
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            4407..5408
                     /locus_tag="KRN00_002811"
     CDS             4407..5408
                     /locus_tag="KRN00_002811"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBH1828667.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     gene            5512..5901
                     /locus_tag="KRN00_002812"
     CDS             5512..5901
                     /locus_tag="KRN00_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBH1828668.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            6062..7270
                     /locus_tag="KRN00_002813"
     CDS             6062..7270
                     /locus_tag="KRN00_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBH1828669.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(7356..8432)
                     /locus_tag="KRN00_002814"
     CDS             complement(7356..8432)
                     /locus_tag="KRN00_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1828670.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDIYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            8661..9188
                     /gene="hpt"
                     /locus_tag="KRN00_002815"
     CDS             8661..9188
                     /gene="hpt"
                     /locus_tag="KRN00_002815"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBH1828671.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            9277..10209
                     /locus_tag="KRN00_002816"
     CDS             9277..10209
                     /locus_tag="KRN00_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBH1828672.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVIF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            10271..11497
                     /locus_tag="KRN00_002817"
     CDS             10271..11497
                     /locus_tag="KRN00_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1828673.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            11581..11802
                     /locus_tag="KRN00_002818"
     CDS             11581..11802
                     /locus_tag="KRN00_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBH1828674.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            11991..12161
                     /locus_tag="KRN00_002819"
     CDS             11991..12161
                     /locus_tag="KRN00_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828675.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(12254..12715)
                     /locus_tag="KRN00_002820"
     CDS             complement(12254..12715)
                     /locus_tag="KRN00_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828676.1"
                     /translation="MQIEQLDLETRNKIYCYTKKILIKYQKGITSGKLTADKFADNIL
                     SQDFISSILNEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQIT
                     QLKNLLSNTGYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKA"
     gene            12898..13365
                     /locus_tag="KRN00_002821"
     CDS             12898..13365
                     /locus_tag="KRN00_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828677.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
     gene            13408..15171
                     /locus_tag="KRN00_002822"
     CDS             13408..15171
                     /locus_tag="KRN00_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBH1828678.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNETIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            15179..15787
                     /locus_tag="KRN00_002823"
     CDS             15179..15787
                     /locus_tag="KRN00_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1828679.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            15859..16428
                     /locus_tag="KRN00_002824"
     CDS             15859..16428
                     /locus_tag="KRN00_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBH1828680.1"
                     /translation="MKLPIALSNKHVHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
BASE COUNT         6494 a         1680 c         2935 g         5494 t
ORIGIN      
        1 aaagtaagta attataagct atttaatcgc tggaataaat ttacaataaa aaaataaata
       61 caaaggcttt atcattaagg tattggcata agttttgctt attaaacaag tatactaata
      121 aaattcattt aaacaggagg gagaatttat atgagtaaat tagaatcaac aacagaaaaa
      181 gttgaggtaa aatggtatgg gtatgtagca ttaatattgg gagcattatt tttttcagga
      241 atatttaaag atgcaccagg accattaaaa gtattggatt ttaacaatgt attaggttct
      301 tttggaacat tgggaacaat taatgatggt gtaggtacat tagctgcaaa ctttagaggt
      361 gatggaggta ctggccctcg agatggatgg ctatatgcat tgacattaat accatcagtt
      421 atgtttgcac ttggagtagt tagagttata gaccacttag atggaatgaa ggcagctcaa
      481 aagcttctta gtccactatt aaagccatta ttagggttac ctggatttgc aggactaact
      541 ttgatagcta gtttacagtc tacagatgca gctgcatcta tgactaaaga acttaaagat
      601 gatgggtata tagatgaaaa acaaaaagct gtattttgtg catttcaatt ttcaggtgcg
      661 tctgcaatta cgaatttctt tgcttctgga gcagcactat ttccatttat aggagatgta
      721 ccaatattta taccacttgc tttaatatta attatgaagt ttgttggggc gaacttactt
      781 agattatatt taaataaatt tgacaagggg gaagcttaac atgagtgagg tagcaaaaaa
      841 agaagtaaaa gttaaaaaag gaaatgtgat agatgcgttt attggaggag ctagaaatgg
      901 attccaaata agtacaaatt caatggctcc aaatgtcatc ttcggttttg ctataatttc
      961 tgtgttcaat ttaacaggtc ttttagatgt aatagggaca atatttacac ctgtaatgag
     1021 tatctttgga cttccaggtg ttgcagcaac agctataatg acaatattta tatcaatggg
     1081 aggagcatct ggagtaatcg caggtttatt tacagcaggt caaataagtc aagcacatgt
     1141 tgcaattcta ttgccaatgt tattgctttc aggagcgcag atacaattta tggggagact
     1201 tttaggaaca gctgagttaa aaactaaata ttatccacat atgtttgtta tagcaacttt
     1261 aaatggttgt attgcaatgc ttataatgaa ttatttcgta gtataggtaa ttataataaa
     1321 aatttaatat aaatggaaag tttaaatttt aaggaggagc tagattatgg gaactaacaa
     1381 agattatatt gagtatgtac ataaagtgta tgattatcta cacactatac cagaaaaagg
     1441 atttgaagaa tataagacat cagagtttgt tttaaaagag cttgaaaaaa tggggtttga
     1501 aaatattaat aaaggagttg caggaactgg tattatagta actatagatt ctaaaaaaga
     1561 aggaccagta tttgctataa gagcagatat ggatgcattg gaatttatca tagatggaga
     1621 aaagaaaatg atacatgctt gtggtcatga tggtcatact tctatgcttt taacagctgc
     1681 aaagttaata aaagagagaa atttagtaaa aagaggtaag ttaaaaatac tttttcaacc
     1741 aggtgaagaa aaattatatg gagcattaag agtaattgat tctggtttgc tggatgatgt
     1801 agaagaaatg gtagggatgc atttaagacc tggacaagat tgtaggttgg gaaaggcgat
     1861 acctgcaatg taccattgtg ctagctgtat aatggaattt acgattaaag gtatcacttg
     1921 tcatggttct aaaccacatt taggagtaaa tgcagtagat gctgtctgtt tagcagtgaa
     1981 tgcaataaat gcaataagag taaatccagc tataccaaat tctataaaag taacaaatat
     2041 atcagttaag ggagaaactt ataataatat accagatgaa gcatttatgg ctttagatat
     2101 aagggcagaa agtaatgata taatagaaga attaaaagaa aaagcaatac atgctgtaaa
     2161 aactgttgta agttctataa atgcagaagc tgtactaatt tccaaagatg gagtaccagc
     2221 agcagaattt gatgaagaac ttgtaaactt ggctgaagaa actataaaag atgtattggg
     2281 agctgatgca tctataggta tatttaaaaa ttctggtgga gaagacttcc attattatac
     2341 acaaaaacta aaatgtaaaa ctacatatat tggattagga gctgatgcta caccaggatt
     2401 tcataatcca aatgtaacat ttgatacgaa agctttagaa tatggtgtag atatatggtg
     2461 tagattggtt gaaaagagat tgggataaca tccaaactaa taattctaca tttaaaatta
     2521 taattataga agttatagaa aaagattgct tatgttaatt agaaaataat taatatgagc
     2581 aatcttattt tgatataatg aaactgattt tggaatattg aaaaaatatg atggaaaagt
     2641 aattatattt taaatctatt ggacaaaaaa gtgatattat tataatatta agaattgtaa
     2701 aataatacca aagtgcatct agtaatagac ttaacaatta taaaaatttt attcttagga
     2761 gggaaaaaat gagtaagtat aattttgaca gagtaataga tagagtagga acagattgtg
     2821 taaaatggga ttttagaact aattgttcaa caaaagcaca aaaagatggt ttgccttttt
     2881 ggattgctga tatggatttt gaatgtgcag aaccaataat agaagcatta cgtaaaaaag
     2941 ttgaacataa aatatttgga tatagttcaa atgatagtga taaatacttt aatgcagttt
     3001 gtgattggta taaaaggaga tttaactggg aaataaatag aaaagatatt atttttagtc
     3061 ctggtgttgt acctgctgtt gctattttag taagaatatt aactaattct aatgaaggtg
     3121 taatagtcca aaaaccagtg tattacccat ttgaagctaa gataaagagc aataataggg
     3181 acgttgtaaa caatcctctg atatatgaga atggtactta taggatggat tatgatgatt
     3241 tagaagaaaa agctaagtgt agcaacaata aagtactaat actttgtagt cctcacaacc
     3301 ctgttggaag agtttggaga gaagatgaat taaaaaaggt tgtagaaata tgtaaaaaat
     3361 atgacctatg gataatagct gatgagatac attctgattt aattagaaaa ggatttaaac
     3421 atactccttt acagtcatta tgcccagagt acaaggataa aatagttaca tgtatagctc
     3481 caagtaaaac atttaatctg gcaggaatgc agttgtctaa tataatagtg aataatgatg
     3541 aactaaaaaa gaaatatcaa gaagaggtta cagctgttgg agttgcaact tcaccaaatc
     3601 cctttgctat tgtagctaca atagcagcat ataatgaaag tgaagactgg cttaatgaat
     3661 taaatgatta cttagataat aatatacaat ttattgatga atacttaaaa gaaaacctac
     3721 caaaagtaaa acttgtttat ccagaaggaa catatctagc atggttagat tttactgctt
     3781 atggattaaa tgaagtagaa cttgaagatt taatgtttaa aaaagctaat gtattatttg
     3841 atgaaggtta tatatttgga aaagaaggaa taggatttga aagaataaat gtagcttgtc
     3901 cacagtcttt attaaaagaa tgtatggaca gattaaagac tatatttgaa aatttataaa
     3961 gtataggtaa aaatttataa agtgtttaaa aataaaaaaa taataaactt gacaaatttt
     4021 aactaatcac ttatcatact attatgaata aatagaaaac ataagagagc taaattttat
     4081 tgaattaaac tcttaaagac tttgaaagga agagtagtta tagaatgtaa ttaaagcgag
     4141 ttggtgatgg tgtgagacca atatgaagtc tatagtgaag aacatcctgg agttgctaac
     4201 cgaaatttta aaagagtagg cttagtcgga accaaaccgt tatcatattg gggtgtatcg
     4261 agtaatatct gtacattgtg agctgggttt gaatttattt caaactaatc agggtggtac
     4321 cgcggaaaag taacctttcg tcccttttat atagggatga agggtttttt taatggaaaa
     4381 atatataaat atagggagtg aatgatatga gcacaataat accaaaggat tataaaagta
     4441 gtttgaacgt aattgataca caaatagcta taaaaaaatt aaaagatttt tttgaaatga
     4501 gactaagtaa tgaattaaat cttataagag tttcttctcc gttatttgta ttgccagaaa
     4561 caggtgcaaa tgataattta aatggagaaa aggctgtaag ctttgatata ccatttatga
     4621 ataaaaatgc agaaattgtt caatcacttg caaaatggaa aagattagcc cttaaaaaat
     4681 atgggtttga agttggtagt ggtttatata cagatatgaa tgcaataaga aaaaatgaag
     4741 aattagacaa tatacattct ctttatgtag accaatggga ttgggaattg gttatagata
     4801 aaagtagtag aaatgaaaag actctaaaag atgttgtaaa aagattgtat ggagtattta
     4861 aagatactga aatttttgta tgtagtatgt atgaaggtat aaaagaaata ttaccagaag
     4921 aaataacttt tataacatca caagagttag aagatatgta tccagaatta tcaccaaagg
     4981 aaagagaaga taaaattgta aaagagaaga aagcagtatt tataactcaa ataggaaaaa
     5041 cattaatatc aggagaaaaa catgatggaa gaagtcctga ttatgatgat tgggaattga
     5101 atggggatat attattttac aatcctgttt tagattcagc attagaatta tcttcaatgg
     5161 gaattagagt tgatgaagaa tctcttgata gacaattgaa acttgctgga tgtgaagaga
     5221 gaaaagagtt tgactatcat aagatgcttt taaatggcga acttccgtat acaattggtg
     5281 gaggaattgg tcagtcaaga atatgtatgt atttcttaca aaaagctcat ataggagaag
     5341 tacaagttgg agtatggcca caggatatga ttcaaaattg tagtagtgca ggaattgaat
     5401 tattataatt taaatataaa ctaattgata aaatttatat ctaatatgtt catcaaatta
     5461 attatatcgg ttataatgta gaataaccta taattataag aggtgataaa tatggagttt
     5521 ttaaaaataa tcattaatat agttttagat attttaaaaa aaattttggt cagatttaaa
     5581 aatgctaaat ttggtttggt ttttgtattt gatttactta aactacctga ttttatgaca
     5641 gataaaagaa tcaatatagt tgataaaata aaggtaattt ctgtattaat ttttactata
     5701 tcctactttg tatctggggt tgatataatt ccagagatga ttgcaggggc atttggtttt
     5761 atagatgatg ctatagtttt aatttggagt ataggtatag tgaatgaaga aattaataag
     5821 tatagagtta tcgcaaaaaa agataaacat tcaaatataa ttgaaaatgt agaattttct
     5881 ataaaagatg aagaagaata acaatttata tatgttattc ttttttttat taacaaaaaa
     5941 tggttaaatt gttgacggag aggtaaaact ctattatcat aataagtgga tatccaatat
     6001 ttaactaagt attcaatgtg caagaatgct taatttaaaa aagttatgga gggtaaatat
     6061 tatgaagaaa aaaataggtt tagtgcccaa actaatcatc ggtatcatag tcggtatttt
     6121 aatcggaagt tatgcaccag aaataatagt acaaatatta gtaacagtta gtactttatt
     6181 ctcagcattc ctaaaatttg ttataccatt tataattata ggttttgtaa cagcaggtat
     6241 agctgattta gcaacaggtg caggaaagtt attggggata actacgggaa tagcatatgg
     6301 ttctacctta atagcaggat tattatcatt tgcagtatct acattaatct tcccaaattt
     6361 tattgatgca agtgttgcaa gtcaaattgg agacccagag gcaggaatgt tagctccaat
     6421 attcacaatt ccattagagc ctatggtaga tgtaacagct gcaatcgtat ttgcatttgt
     6481 aatgggactt ggaatatcag ctttaagaaa tcatggaaaa ggagagactt tatttaattt
     6541 cttccaagaa tttcaaggaa tcgtaacgaa aacgttgtca acagtgatta tacctttatt
     6601 acctttatac atagcaggaa cttttgcaaa tataactata gcaggggaag tatggacaat
     6661 attaggggta ttctggaaag tatacttagt agtaatacct ttacattttg tatatatggc
     6721 atgtcaattc acagcagcag gtgtattttc aggaaaaaat ccagtaagaa tgttaaaaaa
     6781 tcaagtacct ggatatttaa cagctatagg aactcaatct tcagcagcaa ctataccagt
     6841 taatgttggt tgtgcagaaa aaaatggagt aagtaagcaa ataagagaat ttgttgtacc
     6901 tctttgtgca acaatacatt tatcaggtag tatgatatca ataacaggat ttacaactgc
     6961 agttttaatg atgaatggta tgccacatgg aataggtgta ttattccctt atattgcaat
     7021 gttaggtata gcaatggttg cagcaccagg agcaccaggt ggggctataa tgagtgcact
     7081 tcctttccta ccaatggttg gaataccatc agatggtggg cttgcaagtt taatgatagc
     7141 tttatactta actcaagaca gttttggtac agcatgtaat gtatcaggag ataatgcaat
     7201 agcagtagta gtagataaaa taaatgatgg aatgagtaaa aaaggaaata aagaagagca
     7261 aagtgcttag ttttttaata atcaaaaatg agttatctca aatagagata actcattttt
     7321 gatggtataa aaaattataa aataaagtga tttttttatt taaaaattgc tttaagagat
     7381 gatattaata atttattttc attaggtttt aatatacata ctctaaagaa atactcatct
     7441 agaccttcaa atgaacaaca atctcttatt attatttttt gtggaagcag ttgctctcga
     7501 agagatttag cagtcaattc ctttgtcttg attttacaca atatgaaatt acctttagta
     7561 ttgtatatat ctaagctttt tatattctta agctctttaa gcaggtaatc tctttcagtg
     7621 ttcattaagg aaatagtatt tgatataaaa tctaaatcac taaacatgat ttcacccatt
     7681 ttagaagcta ttatgtttat attccataaa tctagatttt tatttatttc atttttgaca
     7741 ttagtgttag atataaggcc atatccaagc cttattccag gcgttgaaaa aaattttgat
     7801 gtacctctta taacgaataa attagaataa tcatcaacta attgagtaca agagtatgta
     7861 tctgtatcag taaactctac ataagtctca tcaatcatta aaaatgagtc tgtatttttt
     7921 aaaatttctc tcacttctac tttagtaaat gcaaatccag ttggattact aggattacag
     7981 attactacca aatcataatc tttagcattg atggttttta taagattttc taaatttata
     8041 tgaaaattat cttcttcttt tgcaaagtat ttttctatag aacaattaat tttagataac
     8101 tctttttcat actctgaata ggctggagag agtaaaagag cttgtttagg attaattgta
     8161 tgtataaatg atgaaattag ttctgtagct ccactgccaa gtactatatt atctatagaa
     8221 catttgcagt aattggatat agaagttttt aagtctatgt aatcagggtc aggatacata
     8281 gataccatat ctatattgtt tacaatgtat tgtttggcta aacttgatgt accaaaagga
     8341 tttatatttg agctaaaatc cataaattct tcctttgaaa agccatactt actagataaa
     8401 ctatataaat tagctccatg gtttgtgctc ataaaagtac ctccaaaaat aaaattatat
     8461 aatcgataaa aataactgat taatatatgt acatatagat tataatacaa aggaatcgtt
     8521 attccaaatt tttaatggaa aaagcaaaaa agtatggata agctgttaat ttaggtttaa
     8581 aaatgatgaa aaagatttta attgatattt tggtatgcta taatatataa gttaatagaa
     8641 ggaaagcggg aggatacaaa atgtacaaag ttacaggaaa aatgttgaca gaagaacaaa
     8701 taaaagaaaa agtttatgaa ttaggaaaaa agatagaaga agactttaaa ggcgaagatt
     8761 tactagtggt aggtatactt aaaggagcta gtgtatttgt ttcagattta ataagatgta
     8821 tagatttgga tgtaaatata gattttatga gtgttacaag ttatggaaac tcaacagagt
     8881 cttctggaac agttaaaata ttaaaagatt tagatgtaga tattgaagga aagaatgtgt
     8941 tgattgtaga ggatataata gattctggtt taacattaag taatctagtt gcagctttaa
     9001 aaactagaaa tccaaaatct ttaaaactat gtactctact tgacaaacct cagagaagaa
     9061 aagctaatat acctgtagac tatgttggat ttgttataga agacaaattt attgttggtt
     9121 atggaataga ctatgctgaa aagtatagaa atttacctta tataggtata gttgaggatg
     9181 tagaatagat ttaaatgtga atcaaaagca ctaatttcta agggagttag tgctttttag
     9241 ttaattatat aaaattttag taaaggagac atctatatgg atattcagtt aaatatatta
     9301 ttatttttcc aaaatttaag aaatccaatt ttgaacttta tatttcttgt ctttacaata
     9361 agcacagaag caccgttatt aatattaatt acaacaatta tatactggtg tataaataaa
     9421 aaatgtggac agaaaatact gtttgctata attggaaatt ttgttgtaaa tttaggcatc
     9481 aaagagtttg taaaagctcc cagaccaata ggaataaaag gtcttgaatc attgagagtt
     9541 tctactgctg gtggttattc ttttccaagt gctcatactc aaactgcaac aacattttgg
     9601 gttagtatta tgactatatt taaaaagaga tatcttcatt taataggtgc agttatggtt
     9661 ttaggagtag gattgtctag gctgtattta gctgttcatt ggccaataga tgtgatagcg
     9721 ggttggatat taggaatatt ttttacagtt atatttgtaa aaatatttga ctatattgat
     9781 gataataaaa attatatttt acttgtagtt ttacttatac catttataat agtggctata
     9841 tttctaaata gccctgaata ttttgaaaaa tttggtataa tagtaggatt tgtatttgga
     9901 tatatggttg aggatagatt tgttaaattt aatacagata ataataacaa aaaaataaat
     9961 tttagtaata aaaataaggg gagtaaaaat ataatttttt caagaatatg taggtttttg
    10021 gttgggatag taacaatagg aatgttatat attggcatta agttgtttat ttcaatgtta
    10081 atagtcactt taaatataag tgactctact atgagtataa tttttatgaa ttttattaag
    10141 aatacagtag ttgtttttta tggaatagca ggagctccag cattatttaa acttttaaaa
    10201 ttaaattgat tttaaggtat agagtcaata gtttaaatta aaaaaattaa gggtagaaaa
    10261 gagtgattat ttgaagaagg tagtaataat aggtggtgga ccagcaggga tgatagccgc
    10321 atcaactgca tgtgagaaag gctatgatgt aacattaatt gagaaaaatc ataaattagg
    10381 aaaaaaactt gcaataacag gaaaaggtag atgtaatatt actaacgctt gtgaaataga
    10441 ggaattaata gaaaatgtac ctacaaatgg aaaatttctt tatagtgctt tttatacttt
    10501 tacaaatgat gatgtaataa gtatgtttaa taatcttgga gtaaagacta aaacagaaag
    10561 aggaaaaagg gtttttccag agagtgataa agcctttgat attgtaaatg ctcttgaaag
    10621 acaacttaaa agtaagaaag taaatatatt attaaattcg aaagtagaaa aaataatatc
    10681 taaaaataat aaaattgaaa aagtaatttt aaacgataaa aaagaaatta agtgtgattc
    10741 agttgtagta gcaactggtg gattaagtta tccacttact ggttctactg gtgatggata
    10801 taaatttgca atttcacagg ggcacacaat tatagataca aaaccatctt taattggtat
    10861 agaagtacaa gaaagtttta caaaagattt agaaaaatta tcattgagaa atgttgaaat
    10921 aagggtgttt aatagcaaac aaaagaaagt ttatagtgat tttggagaac ttgaatttac
    10981 taaatttggt ttagatggac ctataatcaa gtctgcaagt tgtagaatga aagatacaag
    11041 gaaagaaaat tacactatat tattagattt aaaacctgca ttagatgagg aaaaattgga
    11101 taaaagagtt caaaaagatt ttcagaagta tacaaataaa aaatttgaaa aagcattaga
    11161 tgatttactt ccaaaaaaac taatacctat aataataaac ttaagtgaaa ttaatccaaa
    11221 tacggttgtt caccaaattt ctagagagca gagaaaaaac ttagtccatt tattaaaaaa
    11281 tttaaagttt acagtaaaga gatacagacc tattgaagaa gctataataa cttctggtgg
    11341 tgtaaaagta aacgaaataa attcaagtac aatggaatca aaattagtag aaggtttatt
    11401 ttttgctgga gaagtaatag atatagatgc atatacaggt ggattcaatt tgcaaatagc
    11461 tttttctact ggatatttgg caggttttaa ttgctaaaaa ttacctgaat taaaaatgtt
    11521 taaaatcaca taatattatc agcaacacaa aataaattaa acagaaggaa ggtaatcaac
    11581 atggcaagta acaataacaa caacagaaca gtagtaccag gagcaaaaga ggctttaaac
    11641 caaatgaaat tagaaatagc taatgaactt ggtatgagta attatcaaca agttgataaa
    11701 ggaaacctta ctgcaagaga aaatggttat gtaggtggat acatgactaa aaaattagtt
    11761 gaaatggctg aacaacaaat ggctggaaaa agcaacagat agttataaat aattatttat
    11821 aactattggc tattagttta gctagagcta tctcaaatat agaaagtaat ttctaaattg
    11881 agatagcttt tttttattaa attattaaat agatatattt ttatgtaata aattttatgt
    11941 atttggataa aataatacaa atgaatatgt tacataagga gtgatgtaaa atgagtagtg
    12001 taaattttga ggatttaaaa aacaaattta ttaatagtga cttagatgaa aaaataagaa
    12061 tatatacaac aacagaaggt ttatcagtag aacaatttaa agagctacta aaatattatc
    12121 caatacaaca tttatctaaa ctagaaaaag cacttggata gcagtattta atccaaaatt
    12181 aaaaaggcaa tttatttaat attaaaaata ttttttatta aataaattgc ctttttataa
    12241 taggtttaaa ttattatgct tttgatatat aattatagat tctctcattt ccaagttcaa
    12301 tagacccagt attaataaga gtaactattc cttctatatc tctagcagtt aagtatttat
    12361 atggaattaa taaattataa ccagtattac ttagtaagtt ttttaattgg gttatttgag
    12421 agatattgaa acattttgca gttttagtag atttttttct taagttagat aaattttcat
    12481 tttgaatatt tattaaagtt tctatatagt ttctataaga tatcttaaag tttgtctcat
    12541 tgactatttt ttcattaagt atactactga taaaatcttg agacaatata ttatctgcaa
    12601 atttatctgc tgttaatttt ccagatgtta tgcctttttg atattttata agaatttttt
    12661 tagtatagca gtatatttta tttctcgttt ctaaatcgag ttgttctatt tgcacaaaac
    12721 cacttccttc taattataaa aatatttatt aaaaatctat acttaactaa taaagcttca
    12781 ataacttatt tacaataaat actaaatcat aaaatatttg ttatttttta ttattaccaa
    12841 gtataaaaaa tattataatt gtaaaactta caaatatatg taaaatattt aggagtgatg
    12901 aaaatgttaa atgggataat aaagcttttt tattctgaaa ttgtaaaaac aaagattaat
    12961 aacttagatt caagtggata ttctttaaga gatgaatgta aagaaatcag aaatataact
    13021 ctaaagatag atagtgtatt ttttaagctt ttaaagttag cttttggttc aatattgctt
    13081 atggtagctt ttaatttaaa catggtttta ggtataggag tgtttttagt tggtgtagtt
    13141 tatatactat ataaaagaaa tatggaagaa caagtaaaag agcatataaa taatgtgaaa
    13201 aataatatcg acatctctaa aataactttt atggatgaaa aagggagaac aggtctaaat
    13261 gcattaatta cattacttct tataggatta ttgacaggat ttaactggat attagttgct
    13321 agttttgtcg ttgtttttgt ttttactata aagaatgtat gttaaaatac taataaatag
    13381 tttaatatat agggggagaa attgagtatg actaatggca gttataaaat gaagaattta
    13441 gtggaaatat ccgctatggt gactgaatct acagattttt ttaatataaa agatgacata
    13501 atagaaaaaa tgttagaagt tgttcaccct acaaaggcat gtgtgaatct attttataaa
    13561 aatgattcta aatatgccta cttagtatgt tcgcaaacct tagaatatgt acctcaaatt
    13621 tttccaataa atagtcttaa aggtgcaaaa attgattttg acacatatcc agagtatata
    13681 catgaggctg taaatgaaaa aaagataata tatgtggaaa atgtatttga agattctaga
    13741 gcagaaggtg aacgagattt agcaaaagct gaaggttata ttgggagaat agtttttcct
    13801 tttataataa ataacgtagt tgttggattt atgacttgtt ttttaaaaga ggatgattat
    13861 ataacagaac aagatataga ttttatatca tctgttgcat cactcttgag tttatcaata
    13921 gaaataacta ataaaaataa taatgtacaa attttaattg ataaactaag aggctcaata
    13981 agtgccataa atgaagctac taaaaaacta taccttaata agagtattga tggctttttg
    14041 gaaaatttaa gtaaacaagc gtgtaatatt actaatagta aagaagcttt aataattata
    14101 aatagtcatc ataataagga tgctatagtt agttgttata atgttgagca aaaaaagaaa
    14161 acaaatttat atcctatgat tgatatgttt ttaaagaaag agtcattggg ggggtatcta
    14221 aataatttaa aaccatgctc aaaaaaggga ataaatttgg aaagttatat atattacaaa
    14281 cttcaggata aaaatgagac tataggatgt atagtttgtg caaatagcaa aaactatact
    14341 agtgatgatt taaatattct tagtatattg tccaaacaag tttctgttgg tatgcaatta
    14401 tatgaacata atgaaaagga agtaaaacac aaagttcttg aaaacgagtt gaacatatta
    14461 aataaacaac aacagcttat tatggataaa ggtaaaatgg attgtaatga tgagaaagaa
    14521 ctttattttt accataaacc agcaagggta gtaggtggag atttttatta tgctacaaaa
    14581 gtggatgacg aacatatagt ttatattgtt gctgatgtaa tgggacatgg aatggtatca
    14641 aattatgttg ttgcaatgat aaaaggtgct tttaaagtat tatgcaatca atacaataca
    14701 ccaagagaaa taatgacaaa tttaaatagg atgttatatg atgaatttga caagatggga
    14761 gtatttacaa cttgtttgat aggtattata gatactaaag aaaatatgat tactgtgtct
    14821 aatgcaggtc actatagtcc tgtagttgta aagaaagatg gcacaataga aaataattta
    14881 aattgtaaaa agggcatacc tattggaata atggaagatg ctacttatga aaataatact
    14941 ctttcaatgg aagattatgc aatggtatgt atgtacactg atggaatttt agagataaaa
    15001 aattcatcaa aagaagagta tggtataaac agattagaaa actttctaaa agaaaatttt
    15061 agattaaatc aacagttaat agtagaaaat ctaaaattgg atttaaagaa cttctcatca
    15121 aaagataatt atgatgatga tattttaata gttatgttaa aggataggta gattgattat
    15181 ggattcaaac gataaaaaag gacttaaaag tccagagatt ataataataa atggaagtcc
    15241 aagaattaat aaaaattgca gttttatagc aaatgaagta aaagctatgc tagaagagtg
    15301 tggattaagt tgtaaaatat ttaatatcta caatatggat attgaatatt gcacagcatg
    15361 tggattttgt gaaaaaacag ggtattgcaa gtttaatgat gatatgaagc cattatataa
    15421 aatgtttgat gattcaaaag gaactatagt aataagtcct gtacattttg attcaatatc
    15481 agctaaatta aagactgttg ttgatagaac tcaagctata tatgcaagta aatatgtatt
    15541 aaataaacct tcaattgata gaagtaagaa acggatagga atgtatattg cagtgggggg
    15601 gagtaaatca tatgattcac agtttaaagg tggacagatt gttatggatt ttttctttaa
    15661 gagtataaat actaaacttt tacacaatat atatttaaac aatacagatg atgtatctta
    15721 tatagataat caagaattta aagatataat atataaaaat ttaaagatat atattgattc
    15781 aatataattt gattttgtag gtaatattat gtataattgt attgcaataa tttaaataat
    15841 taaaaggagg gaatttcaat gaaattacca atagcattat ctaataaaca tgttcatttg
    15901 agtcaagctg atatagacgt attatttggg gcaggtcatg agttaactaa atttaaacca
    15961 ttatctcaac cagggcaata tgcctgtgaa gaaaaagtgg atttagtagg accaaaagga
    16021 actttaaaag gagttagagt actaggacca gctagagctc atactcaagt tgaaatatct
    16081 ttagcagatg gtttcccatt aggagtaaaa gcaccaataa aagaatctgg tgatatagct
    16141 ggaactccag gtgttaaatt agtaggacct gctggagaag ttgaaatgaa agaaggagtt
    16201 atagttgctt ctagacatat acatatgagc aatgaagatg ctgctaaatt tggtgtaact
    16261 gataagcaaa tagtaaaagt taaaacatct ggaccaagag cattagtatt tgaaaatgta
    16321 ttagtaagag ctagtgacag ttttaatcta gaaatgcatg ttgatatgga agagggaaat
    16381 gcagcaggcg ttaaaaatgg agatttagta gaattaatag ttgattaata ttataaatag
    16441 actttatgct agtagatatt ttatttgcta gcatattttt aaatgtaata aatttctata
    16501 ggataaattt aatcgattag attaatttat aaaataaagg ggtattataa aaaatgtaat
    16561 aaaaacttac aaaaatatga tgtaatatgg taaaattata tat
//
LOCUS       DAEQAF010000083        15785 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.086, whole genome shotgun sequence.
ACCESSION   DAEQAF010000083 DAEQAF010000000
VERSION     DAEQAF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15785)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15785)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15785
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.086"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..572
                     /locus_tag="KRN00_002825"
     CDS             <1..572
                     /locus_tag="KRN00_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBH1828681.1"
                     /translation="CKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFTDVNREEKIN
                     DIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKFLGYKQNTNV
                     NAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWKVYGDTKQSE
                     DTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(670..1629)
                     /locus_tag="KRN00_002826"
     CDS             complement(670..1629)
                     /locus_tag="KRN00_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1828682.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(1663..2394)
                     /locus_tag="KRN00_002827"
     CDS             complement(1663..2394)
                     /locus_tag="KRN00_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828683.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(2387..3157)
                     /locus_tag="KRN00_002828"
     CDS             complement(2387..3157)
                     /locus_tag="KRN00_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828684.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGANKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(3242..3952)
                     /locus_tag="KRN00_002829"
     CDS             complement(3242..3952)
                     /locus_tag="KRN00_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH1828685.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(4132..4284)
                     /locus_tag="KRN00_002830"
     CDS             complement(4132..4284)
                     /locus_tag="KRN00_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBH1828686.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(4310..6466)
                     /gene="feoB"
                     /locus_tag="KRN00_002831"
     CDS             complement(4310..6466)
                     /gene="feoB"
                     /locus_tag="KRN00_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1828687.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(6566..6787)
                     /locus_tag="KRN00_002832"
     CDS             complement(6566..6787)
                     /locus_tag="KRN00_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1828688.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(6800..7012)
                     /locus_tag="KRN00_002833"
     CDS             complement(6800..7012)
                     /locus_tag="KRN00_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1828689.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(7333..10230)
                     /locus_tag="KRN00_002834"
     CDS             complement(7333..10230)
                     /locus_tag="KRN00_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1828690.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEKFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(10557..11165)
                     /locus_tag="KRN00_002835"
     CDS             complement(10557..11165)
                     /locus_tag="KRN00_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBH1828691.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISYQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKYLA"
     gene            complement(11425..11970)
                     /locus_tag="KRN00_002836"
     CDS             complement(11425..11970)
                     /locus_tag="KRN00_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH1828692.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(12088..13911)
                     /locus_tag="KRN00_002837"
     CDS             complement(12088..13911)
                     /locus_tag="KRN00_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828693.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDIDTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMISNINVVKSFNYERKSLNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KSGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTVLSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(13924..15699)
                     /locus_tag="KRN00_002838"
     CDS             complement(13924..15699)
                     /locus_tag="KRN00_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828694.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRARIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
BASE COUNT         5243 a         2829 c         1560 g         6153 t
ORIGIN      
        1 gttgtaaaaa taaaattgaa tcatcatata taaaatggct tttagaagtt ttaggtccag
       61 tctttttagg ctctaaacct gctgaaataa taaatatttc gtttactgat gtaaatagag
      121 aggaaaaaat taatgatatt tataaatatc tatataaatg taagaaaata gattttatag
      181 ttattgataa agaaaaaaag ggattaaaaa tcttatttgt aaataaaaaa gcattatcag
      241 aaaaattaaa atgtaaaaaa acagtaaact ttttaaagtt tttaggatac aaacaaaata
      301 cgaatgttaa tgcttattta gagcatttag tagataaact taagagtgat gtttttcctg
      361 atgaaatagg tattttttta ggatatcctc ttaaagatgt gattggattt atgggatata
      421 gtaattatga agtttctatg attaaatatt ggaaagttta tggtgacaca aaacaatccg
      481 aggacacata ttcgaagttt ttacttcacc gtaagaaaat gagaaaatta ctagactaca
      541 taagtgtaga taaaatagta agctgttttt aattatgttt ttgtataata ataaaaatac
      601 accctctttt accatacagt ttccataata aataagggtg tattttccac tttaatattt
      661 taaagtattc taattttgat tgtacaacat atctttaata tttattttct tttgttgcat
      721 tccattagac atcaaaaatt cctgtgtatc ttctaattct tttatatcct tgtccgttat
      781 tttagaacta aagtcatacc aagaatacat ttcttttgtt tcatctaaag ataaaccaac
      841 ttctttagat acaacatcca tcacttcatc cttgttttca ttcatatatt ttaaagtttc
      901 ttcatgaacc ttcataaatc tttttactaa ttcaggatat ttttcagcaa agtcatcact
      961 tacagcagta actattattc cacttactaa tccttctcca tttacaatca ttttggcacc
     1021 tgaatttatc gttttcaatg ccactggacc tgcaagcatt gctacatcag cacttttact
     1081 ttctaatgca gaagcagcac taggaatatc catatttaca tattcaacat catctatagt
     1141 atagccttct ttagcaagtg cagcaatcaa cagttgatga agtatagtcc cctttggacc
     1201 tacaattttt ttacctttta agtcttttat agatttaata ttatcattat tagttataag
     1261 catatatcct tttggtgaac ggctataaat attcgtaatt ttaagaccaa caccatttga
     1321 tgcagctatt attgcagacg ttcctcctaa tgcatgtaaa aagtctagct cacctgctgc
     1381 taatgcttga gtttgctctg gtcctgttgt caattcatgg aaattgactt ttatattgtc
     1441 ctttttaaat tcctttccaa ataaatcatc ctttttttct aatatactag gaacattaag
     1501 tggtgatttt acataagtta aatttatttc cttaggtaaa ctagcctctt tttttgcagg
     1561 ttcatctttc ttatcatttg ttgttgaaca tcctacagtc ccaaccaaca ccattattaa
     1621 agatgtcatt actgctaaaa tctttttgtt tcttttaatc aattaaaact cccccaattc
     1681 ccttaatatt tcttttttca agtttatata atagttttta gttaaatctc tattatattc
     1741 atcttcgaca ctaaattgtt taatcctttt atttttacta aaaacaatta ttttctttgc
     1801 tatttccata gcttcttcaa tattgtgagt tacaaatact acaccttttt tagtattttt
     1861 atggatattt acaacttctt tttgcatttt tcttcttgtg aagtaatcta gtgctgcaaa
     1921 tggttcgtcc atcagcaaaa tatcgggatt gaaggaaagt gctcttgcta tacttactct
     1981 gtgagccatt cctcctgata attcatttgg atatgagttt ttaaactttt caagcttcat
     2041 catttttaaa tacttgtcta aatcaacttt atttctatta tctttttcag tatgtaaaag
     2101 tatattttca cttacattca gccatggcat aagtctactt tcttgaaata ccattcctac
     2161 ttttggagta cactttttat cattattaaa aaaatatatg tttccactag tagcattttc
     2221 aagccctgct aaaattctaa gtagcgttgt tttcccacat ccactttcac ctaatataac
     2281 agttatctct tcactagata tatttaaaga tatattatca agaactaaat gctctttatt
     2341 atcaactaaa tatttcttat atatattctc tagcaaaaat ccacttctaa ccatttaaat
     2401 caacctgctt ccctttgcta aattttgtta ttatctttga aaatagataa tctgaaagta
     2461 tacctaaaaa tccaataaca aaaattccta ccaatacaac atcagttcta gacatatctt
     2521 ttccatcaga aatcaaatat cctagtcctg aagaagctgc aataagctct gctccaatta
     2581 tagccctaaa actataccca agccctaaac taagtccaac aacaatatcc agcatagaat
     2641 tagggattat tattttataa aaaattctct ttttagataa attaaaagat ttacctactt
     2701 ctattaattt attgtcacaa ttttttatac ctttcaatgt atttaaaaat attggaaaaa
     2761 aggatgccaa aataataatt ataattttag attcttcacc tataccaaac cataaaataa
     2821 gcattggcac caaagctagt ggaggtgtac ttcgcataaa ttcaaatagt ggtttgaaat
     2881 attcatacat ttttttattt gctccaaata aaactccaag tggtatagcc atcaatgaac
     2941 ttattaaaaa acctattaat atccttctta cactggcata aacatttaag aaaatagaac
     3001 cgtcatatat catttttata aaagtatcta agactatttc aggaggaggc agaatatagc
     3061 tactccatat acccaaaaca catactatct tccataaaat taaaattatt aaaaaaatat
     3121 aatatccttt aagcctttta tgaattttct caaacatata aaactccttt taacatatct
     3181 atccctgcta ccctttttat tttttaatat cttaaataat aattaagcta tatcataaga
     3241 tttaatctat gccaagtctt aatccacctg aactcattct atcagaaggt gtagaatctg
     3301 tttttaagcc agacaatctt tcagatggtt gtataatgac tatttgtcca ggttcaacaa
     3361 attccatatg ataagattct cctgaagtct gaccaataaa agtcttccat gatagttttg
     3421 atactttagg atatggttct cttccagtcc aagctactaa tgcatctggg tcaacacaac
     3481 aaggtccttc aagaattaga ggattaccat ctgttattat agcaacatct tgattttgac
     3541 ctgttttatt tactaaatgt gtagtaaaaa gacctttttg agatattacc cctgaaccaa
     3601 tcaattttac actgtaattt aattgttcag aaaatgccaa taagttttca ctctcaacat
     3661 aaatggaatc acctgggtca attgatatta catctacatg gtaagcattt tgagctaggt
     3721 aaatttcacc ttcaccttca accaccatta ttggcatttg ttctcctgtc aatgacctct
     3781 gaacatgacc taataatgct cttcccaatc caccgccatt acttggacct aacagcaatt
     3841 tttcaaaatt aaaatttcct ttaaaggcta ccatagcacc tttttttgca aaaaatttac
     3901 cacttcccct tgctatacac ataagctcgt ttgtaacatc aaatttaaac ataatattca
     3961 cttatattgc ttaatttagc aataatccct cctaatcata tatttatata taattataca
     4021 gtaaaattac agcatagtct aacctacttc aaatatgaaa tttgttattt atacaaaaaa
     4081 taagaacctg ataataaagc aattcaactt tttatcaggc tcttatccta tttatctctt
     4141 agcgctatga caactcttac tacttgagca tccagaacaa ccacatccac aactgctacc
     4201 attctttttt gaatttttaa ccatatacat tacagctagt gccattaata ctactacaat
     4261 agctgctata ataaatgtag ccatattcat cactccttat ttatatgaat taatttttca
     4321 tataacttaa tttacccatt ttttcttttt tcatattttt atttgaataa gttaaaacta
     4381 caaagactac tgctactgct ataaatatag atattattgc cccagcaata cttcctccag
     4441 tacctaaaac taaacttcca acttgattta taagaagagc aattatatac gctgttaaag
     4501 tttggaatcc taatgtaatc catgtccatt tccatgaacc catttctctt tttatggctc
     4561 caatagctgc aaaacaaggt gcacaaagca tattaaatgc cataaatgca aacgcactag
     4621 ctactgtaaa catgcttgca actgaagcaa gaagtgttgg gtcttgctct gttgcatctg
     4681 atataccaaa taaaactcca aatgttccaa ctacattttc cttagctact agacctgtaa
     4741 ctgttgctac tgatgattgc caatttccaa atccaagagg agcaaatatt ggtgcaacta
     4801 tatttcctaa gctagctaat atactatctc cagcatctac catttgtaat gaccaattaa
     4861 atgattgtaa gaaccagatt actccacaag caacaaatat aattgttcct gctttgatta
     4921 taaatgcttt tcctctatcc cacatatgta ttaaaacacc ttttgcactt ggaatatgat
     4981 attgaggtaa ttccataaca aatggagatg gttctcctgc aaataaacta gttttcttta
     5041 atataattcc acaaatgatt atcattgcaa tacctaagaa atacattgat ggagctaccc
     5101 atgaagcacc tccaaataat gcccctgcaa ataatgctat tattggaatc ttagctccac
     5161 atggaatgaa tgtagttaac ataatagtca tttttctatc tctatcattc tctatagtac
     5221 gagttgacat aactcctgga actccacaac ctgaacttat aagcattggt ataaatgatt
     5281 ttcctgaaag accaaactta cggaaaattc tatccattat aaaagctaca cgtgacatgt
     5341 acccacaatc ttctaatatt gataataata agaataaaag catgatttgt ggtacaaatc
     5401 ctagtactgc tccaactcca ccaattagac catcaactac aagtccttgt aaccactctg
     5461 ctacatttaa agaagctaga aaattactta cattgccttg aataatttct ccaaacagta
     5521 catcatttgt ccaatcagtt gctatagtac ccaatgaact tactgctata tagtaaactc
     5581 cccacattat aagtgcaaaa ataggcaatg ctagtatacg atttgttaca atcttatcta
     5641 tcttatctga tacagtttcc ttaccttttc gattcttctt tattatactt gaaattattg
     5701 aactaataaa ttcataacga ttggctgtta ttatactttc actatcatca tccaattcat
     5761 cttcacaatt tctagttatt tcttcaatac tattcaatat tgttttagaa atatcaagtt
     5821 tttgtataac attttcatct ctctcaaata gctttatagc taaccagcgt gtttctacat
     5881 ctatatatgg agtcttttct tctattattt tttcaatttt ttctattgca tccttacttt
     5941 catcaacaaa gggtaatttg aaatttaatt tattgttact acttgcaagt tcaactgcct
     6001 tttcagcagc ttccataatt ccttgacctt taactgctgt tacttctacc actgggcaac
     6061 ctataacttc agatagttct ttaatattta tcttatcacc attcttattt acaatatcca
     6121 tcatattaag agctataacg gtcggtatac ctagctctaa aacttgagtt gtaagataca
     6181 aatttctctc tatatttgat gcatctacaa tatttattac tgcatccggc ttatcatcta
     6241 gcataaaatt acgtgtaact acttcttcta atgtatatgg agataaagaa taaatacctg
     6301 gtaaatctac tatttccaca tctttatttc cttttaattt tccacctttt ttttcaactg
     6361 ttactcctgg ccagttacca acatattgtg atgagcctgt aagcccattg aacattgttg
     6421 tcttaccaca gttaggattt cctatgagac ctatttttat tgacatttcc attccctcca
     6481 ttattattta aatacatcac tgtttgtgat acagaaaatc attctcatta tataattaca
     6541 ttaaccctac tctaattaat ctttattatt ccacaataat tttttctgca tctgacttac
     6601 gaattgatag ttcataatct ctgactgtta cctcaattgg gtcaccaaga ggagctactt
     6661 ttcttataaa tatattaaca cctcttgtaa tccccatatc cattatacgt cttcgtgtag
     6721 ctccttctcc ttctaacttt ttgactttta cagtctctcc acacttaata tccttcagtc
     6781 tgttcatgtc attacctccc tatattatta ttctacttgc cattttttta tctaatgcaa
     6841 ctctagtatc ttttacgtct attattaagt taccatctat cttagaaact attttaacat
     6901 ttgtacccac tacaaaacct atactattta aaaaagtcct cgtcttatca cttcccgaaa
     6961 ttttctttat aactacttct tcacctgtat ttgataatat caatggcatc atataatatc
     7021 cctcctctta aagtaattta aatctacaag caatcgttat cttatatata aattacaata
     7081 ccttaaatct taatctatta aaataatatc ctattttttc cttcttttta caattcctaa
     7141 ttttgattta agtctatcac aatagtatat tttttgcaag tgattattgt attcttttga
     7201 ttttttttct catttgattt attttattaa taaaatcgta aaaattaata caaaaataaa
     7261 gatgctctaa aatagtatac tcaactaata ttaaagcacc tttattatat atgtcattat
     7321 ttacacattg ctttattctt ttttaaaagc gattttttca aactctttta caggcattgg
     7381 cttagaaaac aaatatcctt gtaccatatc acacccaatt tgctttagaa attctacttg
     7441 cgaaatagtc tctacacctt ctgatattac tttcattttc agttcctttg ccattttaat
     7501 gacattagat ataacaattt tttcattatt actctcatct ttttctgtaa aaaatgctct
     7561 atctagtttt aatatgtcaa caggcaattc ttttaaaaga ttaagagagg aatatcctgt
     7621 accaaaatcg tccatagaga ttacaaatcc cttttctttc aaattgttca ttgtatcaag
     7681 taatccttct atattatcta atactgctgt ttctgttagc tctaattcta taagtcttgt
     7741 cggaattttg tatttatcta caattaattt aaacttctct ataaaattac tatttacaaa
     7801 atgcattcga gacaagttta cagatatagg tactactttt tgtccttcat ccatccattc
     7861 tctaatcttt ttacacactt cctcaaatac atagaaatca atatttacaa taaaaccatt
     7921 cctctcaaat acaggaataa attctattgg tggtattaga cctttttgtg gattatccca
     7981 acgaacaaga gcctctgccc ctataatttg ataatctgaa agactatatt taggttgaaa
     8041 ataaacaata aattctccat tattaagagc atctaccatt gaattttcaa tttctttctc
     8101 ttttaatatt tttttgtgca tttccttatc gtaaaaagca aatgaatttt tatgaccacc
     8161 ttttatagtt tttcttgcag tattagctct atccataata gtatttatgt cattatcact
     8221 tttacttatt ttatatatac cacaatctaa aatcaattta taatagttta ttttaggatt
     8281 actaagtatt tgaaccttat tgtaaatatt gtttaacctt gttttaatat catcatctgt
     8341 cttatactta ataagaagaa caaaatggtc agcagaaact cttgcaaaaa tttcatcttc
     8401 ctttaattca cttgcaatag tatttgatat atgtatcaaa gtatcatttc ccatatcata
     8461 tccaaacata tcatttatat atttaaattt gtcaacatct atataaaaca acgcatattc
     8521 ttctggatta tttttagcaa acagtttatt agaatttatt ttaaatttat ctatactatc
     8581 tgctcctgtc aatgggtctg tatatgctat cttccttaga taatcctctt tcttcttttt
     8641 attataaatt atatatttaa tagcaattaa gaataaaata catacaaaag aaataatttg
     8701 tattgaatat tctttaaaaa tcacaccaaa tggtacttta taaggtttgt caatagtatt
     8761 agaatatata caatcactta attcttcttc agtaattttg tctattgatt tatttaaaat
     8821 agacactaat atagggtcag ttttatttga tacccctata cgcatcccat agcttgtgtc
     8881 taaaacagat ataacagata aattctcact ctttccttct cttaaaagtt catcaaactg
     8941 ataagagcta agtatcatta agtttgcttt accttcattt atagcgttta gacaactttc
     9001 tacactctta taagatgttg tcttagcatt ttcaaaactc ttttctatat aagaatcaat
     9061 agacttataa ctactagtta aagcaatatt taaatcatta ttgagattgg tatccaattt
     9121 tcctaccata atcattggaa tatttatgta tggatttgtc aatttcatat taaatcgttt
     9181 tgccttatca ttttcattga ttgagccaca tagcatagtt gccttaccac tttttatgta
     9241 atcaagactc tcattataat tttttgtttt aatatattca aattttatac cacatttttt
     9301 tgatataatt gacattaaat cggaacttat acctttaaat gaattgcttt ctttatcata
     9361 atactctaca ggagaccact ctgaatcata taccatagta agttttgggt ttgctttaat
     9421 aaaattcatt tcttgccgag taaatgctat ggaattattg acctctcttt tgaaatattt
     9481 tttatataat tccaattcat aatacatatc atttattttt aattctttta aagcataatc
     9541 taattctttt accaaattag gtttatcttt tgcagtagca aaataaaaag gttctactga
     9601 aaatttgcta actattttca ttcctttagc atttataata cttccacaaa caaatgcatc
     9661 tgcctttttt tcattgacgg actcaattaa ttcatcaata gaattacagt atatatattc
     9721 aactgaaaaa ttattttctt ctctatactt ctcaaatgca gtattatgaa agtttcctct
     9781 aagtacagct actctcattc ccttaaagga acttatatct tcataaaaca tattattgtt
     9841 actatccttt gtatatagtg cactatattc atatcctgaa cttagtttag gaaaattaaa
     9901 tagtttattt ctttcatcat tcttctgtaa aggtccgagt aagtctattt cacccttttc
     9961 tagtctgtct aaacattctt cccaagaccc ttttacaaat tcatattccc atcttgtata
    10021 ttttgagatt tctcttagat aatcataacc atatcctgta taagaatgct cttttgatga
    10081 ggatattatt ccgtagtcat cacaatatcc aactcttatt ttttttgaat tttcagactc
    10141 atcagcaaag catagtatat tgttaaaaca tgatataata agtaaaaata tcaaagaaag
    10201 tatcaagaag tgctttttaa atgctttcat atttaaaaac ctccaatttg ccaacttact
    10261 ttaacttatt tggttttcta gttgtaacta cttttattgt aatggtaaat atatcaaatt
    10321 gcaatattct catataatat tcttattcaa ctataatgaa tttattatta tctatttaaa
    10381 tacactatct aatattagtt tcttataagt cataaaagca caactaacac tataattcta
    10441 gtgattaatt ttatttcaaa aaatataata acactactaa tattttaaat atcaatagtg
    10501 tcataaaaac ttttcagatt aattaaatct ttctatatat tttataataa tctaaatcat
    10561 gctaaatatt tagacagaaa acttttttct ttaatagtaa atacttttgt ttgaatatca
    10621 gaataattat ttgaatatct atctataaaa ccatgatttg catctaaaat ctcaatttgg
    10681 atattttgtt tcctagaaag ttggtaagaa atagaatcaa catcaaatga atcgtgcttt
    10741 gcaaatacta ataaggtagg acattttgga attacatcca tgtaatctcg aatccgagag
    10801 ccataacaac aaattatgcc atcacaaaaa gaatcttcac tgcatctcca tgcaatagtt
    10861 gctcccacgc tatacccagc aacaaataca tatttatact ctgattttaa atcatttata
    10921 agcttttcaa cttttttata aatatcaaaa ccaacattat ttataaaaaa atcatatgcc
    10981 tcttggactt ttgaatatgg aaaaactctt ttttctccca gaagttcagg acaaaataca
    11041 tcatatccat atttataata cttttgacaa acatcttcta taaagctatt aatcccatag
    11101 atttcatgca aaacaacaat agctacatca cttttatgta tatactttat cagattatcc
    11161 accaccttta caaaacagca aattttttat acttagttta atatattctt ctttacatgt
    11221 caatttactt ttctaaaatc aaatttattt ttggattaat catttatttt taaaagttgt
    11281 gcattattac tattaaatta ttctctatta ttaaaaatat aatcgttaga aataaaaaat
    11341 aaagtacaaa taattaaaaa atatctcact cataacttta aaaattataa gtgagatact
    11401 cctaaaatct actttatatt aaatttattt tccaaaatat ctatttaata atcctaagaa
    11461 tgctttacca tgtctagctt catctttaca catttcatgt actgtatcat gtatagcatc
    11521 taatcctaat tcttttgctt tcttagctaa ttttaatttt ccatcagttg caccatactc
    11581 agcatcaact ctaactctta agttttcttt tgtatctgca actacaactt ctccaagaag
    11641 ttctgcaaat ttagcagcat gttcagcttc ttcaagagct attctcttat aagcttctcc
    11701 tacttctgga taaccttctc tatcagcttg tctactcatt gctaaataca ttcctacttc
    11761 tgtacactca ccaacaaagt tagctcttaa tccttcgatt atttcttcat ctacaccttg
    11821 agctactcct attctgtgct catcagccca atttttttcg cctttcattt cttcaaattt
    11881 atcagctcca actttacata ctggacattg tgctggtgca gcatctcctt catgtatata
    11941 tccacatact gtacaaacaa atttcttcat aattactttc ctcctaaatt ttatatatca
    12001 aattaaattt tttatttatt aagttagtct atatataccc gcaccatata cctttaaaca
    12061 atttttttaa aagttttttc taaatactta ttttccctgt gtcaataata tgtttctata
    12121 ataatgtccc tttaatttta tcaattcttt atgatttcct gattccacaa ttctaccatt
    12181 ttctaaaact attatattat cacaatttga tatggtactt aatctatgag ctataattat
    12241 acttgtcttt ccataagtta aattatttat tgcttcttga attttagctt ctgttgctat
    12301 atctatgtta cttgtagcct catccaaaat aagtattgga gcatttttta atactgctct
    12361 agcaatactt attaattgtt tttgaccttc acttaaatct tcacccctat ccgataatac
    12421 agtactatat ccttcacgca ttttaactat aaatttatgt gcatttgcta ttttactagc
    12481 atatataact tcttcatcag tagcctccag atttccatac cttatatttt ccataactgt
    12541 atcattgaat atataacctt cttgtggaac tactccaaaa caagttctca aatagtttct
    12601 gttaatagag tatatatcct taccatctaa aaatatactt ccttcatcta tatgataaaa
    12661 atttgtaatt agatttataa tagttgtttt tccacttccc gtctctccta tgatggcatt
    12721 tgatgtgcca gatttgattt ttaggtttat attatctaaa attttctttt ttgaatcata
    12781 agaaaaactt acatctttaa gctcaatttc tccctttaca aaatgagagt ttaaattacc
    12841 atctttatta tcgttaatct cacttttaaa catgttatgc acttcttgct cttcttgttc
    12901 atctataatt tcaaaaactc tttcacatcc agctatggct gaaagtaatg tattaaatag
    12961 atttgctaat tcatttaaag gtcttgtaaa ttgtcttaca taacttaaaa aactagctat
    13021 aacccctatg gttataatat ctttagatgc aagaatgcct cctataatac atatagttgc
    13081 aaatcctata ttactaatca cattcataat aggcattaaa agagaagtgt aaatttgcga
    13141 tttaagggaa atatttagaa gtctatcatt gacttcttta aaatcattta gagattttct
    13201 ttcataatta aaagatttta ctacatttat gtttgatatc atttcttcaa tatgtgcatt
    13261 tagttttccc aactcaactt gttgttgctt aaaaaaaact ctagttctct ttgcaataaa
    13321 attactcaca aacattacta tcggtattaa tattacactg caaaaggtta aaattgggct
    13381 taatacaaac atcataataa aagtcatcaa tatgtttaag attcctgtaa ttaactgtac
    13441 taatgaattt gatattcctg tactgatatt atcaacatca tttgtcactc tactcataat
    13501 atctccagta gaacttttat caaaaaaggt tattggtaga tttttaaatt ttaaaaataa
    13561 attacttctc atttctctga ctatactttg agataatcta gctgtacata tccccttaga
    13621 cagtttaact gaaaactcaa ttatataaaa tgaaagtaaa ataattattc cttttaagaa
    13681 aatggatttt gaataagtat cgatatctat tatgtcaact acctttccaa tagtatatgg
    13741 tattacagtt gatataattg aatcaattat tactagcaaa aaaataaatc tagtaatctt
    13801 cttatctttt ttaaagtaca taaaaattct tttaaacgtt tttttaaaat ctttaggctt
    13861 ttcttttttc tttaatctac tgaccttctg atttccagta cttaaattca atatacttcc
    13921 tccttaattt acatcttcac ttactaaatt ttgcaacgca aaaatttttt tataaattgg
    13981 agaactaacc agtaaatctt catgtgtagc aaatccaacc acctcaccct catccaagac
    14041 taaaatctta tcacagtcaa ttatagaact aatcttttgt gaaatagtta ttacagtaca
    14101 tttcttactt tccttttctc ttaaattact tatatactct tttatattct ttcttataat
    14161 tgtctctgta ttaatatcca ttgcactaaa acaatcatca agaattaata tttgtggttt
    14221 tttggctata gctctagcta tagtaattct ttgtctctgt cctcctgata aatttttacc
    14281 cctttggaat aaaacttcat cataagtatt ttcgagtttt gttataaatt gatttgcatt
    14341 tgctatttca catgatttta caacatcctc tttgcatata tctctatttc ccataactac
    14401 attctccaat atactttttc caaacacact actattttga aatactacac ctattcttgc
    14461 ccttaaactt tcttcagaaa tactgtatat actacgtcct ccaatcttaa tatcaccttt
    14521 atcaattata tataattttt gaattaaatt tactaaagaa gtctttcctg aaccagtttg
    14581 accaatcaca ccaatatttt gaccttcttc tattttaaag gatacgtttt ttaatatttt
    14641 ttcatctgta tttttgttat acgaaaaatc tacattttca aaaattatat cacagtttac
    14701 aaactttaaa tctttttctc caacatctaa actttcttct ctctcaatta cttcttcatt
    14761 ctcatcaacc aaaacctcac ttattctctc ataagatgct tttgccctaa caaaaacatt
    14821 aaaaacatgt gaaatcatta taagagatgt taatattcta gtcatatagt ttacataagc
    14881 aactataatc ccaattttaa tttctcctga ataaattaaa tgccttccaa tcagtaatat
    14941 tattattatg gaaacattaa tgattattgt aattgtcggt ctaaaaaatg acatcatagt
    15001 tgtagctttt ctactatttt taaaaagttc atcatttaac tcttcaaagc tttggttctc
    15061 ataatcgtat ctacaaaata gtttaactac ttttattcca cttaaaaact gtcttaattt
    15121 tgaatttact ttatctgtac tttcttgtac atttttaaat aatctatacc ctatcttcat
    15181 attaagcaat attataataa atataattaa aactgcaatt agaataatta ttgacatctt
    15241 taaatttaat tttatagcta taattaaact tcctatacac attattggtg actttataaa
    15301 aactctcatc attccattaa cgaattgttg catttgattg atatcattag taattcttgt
    15361 tattaatgaa gctctaccaa atttatctat ttgttttaat gagtatgtat ttatcttttc
    15421 aaatacatcc tgtcttaaat cataagaaaa atgctgagaa actcttgccg agattacact
    15481 tcttattatt gcaaatattg cacctaaaaa agttatacct atcattatag ctcctgttga
    15541 tagtatgtag tctaagttct tatttgaaac ccctatatct attatttttg ccattatagt
    15601 tggttgagct aaatcacaaa aagcttccaa tgttaaaaaa aatactgctg ttagaaataa
    15661 tactatatat ttttttatgt attttttaaa atacctcatt caatcatccc ttcatagaat
    15721 tttctcatta ccaaaagtat atcataatgg ctaatttaat tgattatatc aattataaat
    15781 atttg
//
LOCUS       DAEQAF010000084        15765 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.087, whole genome shotgun sequence.
ACCESSION   DAEQAF010000084 DAEQAF010000000
VERSION     DAEQAF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15765
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.087"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            122..1078
                     /locus_tag="KRN00_002839"
     CDS             122..1078
                     /locus_tag="KRN00_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBH1828695.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            1255..1410
                     /locus_tag="KRN00_002840"
     CDS             1255..1410
                     /locus_tag="KRN00_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828696.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNTCTSFLVRPY
                     FSDFEHK"
     gene            1540..2553
                     /gene="aroF"
                     /locus_tag="KRN00_002841"
     CDS             1540..2553
                     /gene="aroF"
                     /locus_tag="KRN00_002841"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBH1828697.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKIVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            2575..3639
                     /locus_tag="KRN00_002842"
     CDS             2575..3639
                     /locus_tag="KRN00_002842"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBH1828698.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            3639..4952
                     /gene="aroA"
                     /locus_tag="KRN00_002843"
     CDS             3639..4952
                     /gene="aroA"
                     /locus_tag="KRN00_002843"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBH1828699.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLAFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGKTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            4930..6009
                     /gene="aroC"
                     /locus_tag="KRN00_002844"
     CDS             4930..6009
                     /gene="aroC"
                     /locus_tag="KRN00_002844"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBH1828700.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGIELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            6012..7208
                     /gene="pheA"
                     /locus_tag="KRN00_002845"
     CDS             6012..7208
                     /gene="pheA"
                     /locus_tag="KRN00_002845"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBH1828701.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRAVDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFGLDS
                     SNKKFDLSNVNKYKSLKDELNKKNILVGFPGKSGSFTEEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDITNNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAENNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            7255..8064
                     /gene="aroE"
                     /locus_tag="KRN00_002846"
     CDS             7255..8064
                     /gene="aroE"
                     /locus_tag="KRN00_002846"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBH1828702.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            8076..8609
                     /locus_tag="KRN00_002847"
     CDS             8076..8609
                     /locus_tag="KRN00_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBH1828703.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNNKSLNNVVY
                     NITNAVSENFKFDFKEK"
     gene            8630..9469
                     /locus_tag="KRN00_002848"
     CDS             8630..9469
                     /locus_tag="KRN00_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBH1828704.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNKNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNKLIEYFKKSSIRREA
                     LEK"
     gene            9737..11218
                     /locus_tag="KRN00_002849"
     CDS             9737..11218
                     /locus_tag="KRN00_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1828705.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTDINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLLEDKIEKEMEYALESGQFVMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            11251..14688
                     /locus_tag="KRN00_002850"
     CDS             11251..14688
                     /locus_tag="KRN00_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBH1828706.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQKDILKANKEISSITNSIPGG
                     VQKCTLGETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERIKKEIFKQL
                     YKNKTIELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQLEQEMEQK
                     NLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKYKACNLVFY
                     EDKKKALESIQHQLNTKGIAVYQHRIRRRNGNIIWVSIKGRLIIDDDGIEKGIWILND
                     ITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYNIYKITKNV
                     PYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKVTLTTIFDE
                     DGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDTFIKGNESW
                     QKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVTEIKLEYRR
                     MNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAERDTLTGLYN
                     KGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFEVSKNLKPI
                     FRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTYKISGTVGI
                     SFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISDNNIKLADK
                     CEKSKPVLKEILDSIDNYIYIVNPSTYELLFVNNKVSRLDLEIKLGETCYKSLLKSER
                     PCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECIDSSLYKNK"
     gene            14706..15452
                     /locus_tag="KRN00_002851"
     CDS             14706..15452
                     /locus_tag="KRN00_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBH1828707.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQRKLSDLKVKIVTTDFHVLRSKILAYRNEYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(15401..15709)
                     /locus_tag="KRN00_002852"
     CDS             complement(15401..15709)
                     /locus_tag="KRN00_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBH1828708.1"
                     /translation="MNFLKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
BASE COUNT         6522 a         1540 c         2617 g         5086 t
ORIGIN      
        1 acttacctta taataaattt aatataaata ttaaataata attattaaaa tagtgtaaaa
       61 taattacagt aaggattata aaaaattttt agaatgtaaa ttgaaattta ggagtagatg
      121 tatgtatata ctgaatttaa atacaagaga gactattgaa gattttagag ataaatttta
      181 tgtagcagaa aattcttatc ttatattaag tgctccaaaa aatttaaaat tgcttaagga
      241 aactttggat atagatgaaa taacttttaa tgattgtctt aaatttgatg aaataaccaa
      301 acttgattta tttgataatt acgatttttt aagcctaaat acatttgaac taagagatgg
      361 agaagctgtt atagaagagg taaatatgta tttatcagat aattttatat tggttgtagt
      421 gaatgaagaa cactttttat tcgaatttgt aaaaaatatt attttgaaga actctcaact
      481 tgaaaaaaat ccagttatta atctatttaa gataaactac ttgattctta gagaagttat
      541 aaaaaatggt tttgagtctt tggaaaaagt tgaagagtta attcttcaaa tagaagatga
      601 aatgatggac aacattaata agaatcatgt atctagaata agtgatgtaa gaggattaac
      661 aagaattata gttaagaata ctagacctct tttgtatatt ggggatagaa tagttaagga
      721 aaatataaga tatttaaaat attcaaatgt aaaaaaatat aatttagaaa attttcaagg
      781 tatagatttt ggaattgaca aattatacaa tttcgcattg tcaacacgag agttagcaga
      841 taaattatta gatatttatt cttccagagt aggtgagaaa acaaataact taattacaaa
      901 attaaccttg ttaacagcca tatcagcacc acttacaatt ataactggta tatatggaat
      961 gaactttaga tatatgccag aattaaactg gatttatgga tatccagcaa ctttattttt
     1021 tatgctatgt ataatttttg ttggaattat aatatttaaa ataaaaaaat tattgtaaat
     1081 tacagatgat atttaattga ttttataaaa atacatcaat tgagaagctg atttaagtaa
     1141 ataaaaaaat attttaaatt gaaaatattt atagaaaata ttgacaatta tattttcttt
     1201 gttataatta ttaaacaaga agaataataa attataaaaa tggaggataa tactatgaaa
     1261 ggaatattaa aagaactaac agcaaaactt tatagctttt tttactttat gttctggggc
     1321 ttttatttta gcgctggcta tttcttttac aaaaatacat gtacttcctt tctggtgagg
     1381 ccttatttta gtgattttga gcataagtaa attttataaa aatgattatt ttatatattt
     1441 atataagatt tagtgcttga tagattattt tagagaactc attagtgagt tctctttttt
     1501 attttaaata taaaattata atattgggag gtagtaaaaa tgatagtagt attaaaaatg
     1561 ggagcagata aaaatgaagt taaaaaatta attgaggcta ttgggagaga aggagtagaa
     1621 gttaatccca tagatggaac agaattaact gttttaggtt tagttggaga tactagtaaa
     1681 atagatgcca aaagaataga agcaaataag atagttgaaa aagttatgca tgtagtagag
     1741 ccttttaaaa aggccaatag aaaatttcat ccagaacctt caatcataaa tgttaatgga
     1801 atggaaattg gttcaaagaa aattgctatg atagctgggc cttgttctgt tgaaacagaa
     1861 gaccaaatag tatctatagc taaagatgtg aaaaaatcag gtgcaggatt tttgagaggt
     1921 ggagcattca aaccaagaac atcaccatac gctttccaag gattgaaata tgatggattg
     1981 gatttattaa aaaaagcaaa agaaaaaaca gggcttccta tagttacaga aataatgtca
     2041 acacaagata tagatatatt tgaagaaaat gtagatgtaa ttcaagttgg agctagaaac
     2101 atgcaaaact ttgatttatt aaaagaatta ggtaaaacaa ataaaacaat acttttaaaa
     2161 agaggattat ctgctacaat tgaagagtgg ctaatgtcag cagagtatat aatggctgga
     2221 ggaaatgaaa atgtagttct ttgtgaaaga ggtataagaa cttttgaaac atatactaga
     2281 aatactttgg atttaagtgc aattttagct gtgaagaaac ttagtcattt accagttata
     2341 gttgacccaa gtcatgcagc aggtaaatca tggatggttg actctttatc taaggcagca
     2401 attgcagttg gagcagatgg tctaataata gaagttcata atgacccagc acatgcactt
     2461 tgtgatggaa aacaatcgat taagccaaat gaatatgatg aattgataag tgaattaaag
     2521 actatcgcat cagcagttgg tagagaaata taatctataa aaggatggtt aaacgtggaa
     2581 gaaaaactat tagtaaattt aaaagaaaat agctacaata tatttattaa aaaaaatata
     2641 ctaaagaata taggagaaga aataaaaaaa atatattttg gaaataagat ttttattgta
     2701 actgatgaaa atatagcaaa attatacttg gataaagtaa aaaataattt aagtgaatct
     2761 ggatttgaaa ttaaatcttt aatattaaaa tctggtgaag aaacaaaatc atttaatact
     2821 cttcctaaaa tatacgatag tttacttgac tttaagttaa ctagaaaaga tttgattatt
     2881 actttaggag gaggggtaat aggtgattta ggtggatttg cagcagcaac ttttttaaga
     2941 ggtataagtt ttattcaaat tccaacatct ttattagcac aagttgatag ttctgtaggt
     3001 ggaaaagttg gagttgacct tgagagaggc aaaaatttag tgggaagctt ttaccaacca
     3061 aaggctgtgt ttatcgaccc aaatgtatta ttatcacttc cagaaaaatt ctatagagat
     3121 ggaatggcag aagttataaa atatggatgt ataaaagaca aaactttttt caataaactt
     3181 ttaagtttaa aaaatagaga agaagtaatg caacatatag aatacattat acataaatgt
     3241 tgctttatta aaaaaactgt agttgaagct gatgaaaaag actttggaga tagaatgctt
     3301 ctaaactttg gccatacatt aggtcatgct attgagaaat actacaattt tacaggttat
     3361 acccatggag aagctgttgc cataggaatg tataagataa ctttagaaag tgaaaagata
     3421 ggaattacaa aaaaagggac atcagaactt ataaaatcaa ttttaatgaa ttataatttg
     3481 ccttatgaga ttgaattaag agataataaa tctatagtag atgctatatc tcttgataaa
     3541 aaaaatctag gtgatacatt aaaaataata cttttaaaag atattggaga gagtattata
     3601 tataatacta cttctaaatt ttttcaggag gtaagataat gggaagtcta aaaatatatc
     3661 caagtaaatt atctggagat gtaaaaatac caccatcaaa aagtatggca catagggcag
     3721 ttatttgttc atctctaagc aatggaaaaa gtagaatttc taatatagat ttttctgatg
     3781 atataatagc tactataaga gcaatgacat cattaggagc tattatagaa aagaaagaag
     3841 atattttaga aatttcggga attttttcta aagaaggtat tttaaataga gagaatcagt
     3901 tgaatcaacc taaattgaca atagattgta atgaatcagg ctctacattg agatttttag
     3961 tacctatatc tttagcattt gatggtgtaa aaaggtttat aggtagagga aatcttggaa
     4021 aaagaccact tgatacttat tatgagatat ttgacagaca gaatataaaa tatagttaca
     4081 aagaaaatca gttagatttg attatatcag gtaagcttaa accagatgaa tttagagtaa
     4141 aaggaaatat aagttctcag tttatcacag gtttactgtt tatattgcct acgctagaga
     4201 gtgattcaaa gataataatt actactgagc tagaatctaa aggatattta gatttaactc
     4261 tttcaacgat aaaagatttt ggggtagaaa ttataaacaa taactataaa gaatttatta
     4321 taaaaggaaa tcaaacgtat aaagcgagag attataaagt agaaggagat tattctcaag
     4381 gagcatttta tttatcagca gatgctatag gagaagatat tagcatatta gaccttaaag
     4441 aagattctct tcaaggggat agtgaagtag ttgaaatttt atctaggatg ggaatggaaa
     4501 tattaagaga aggcaacaaa ataaaaggaa taacaaatgg tttaaatggt actttgatag
     4561 atgcatctca atgcccagat ataatacctg tattatctgt agtagcatcc ttaagtatag
     4621 ggaagactac aataattaat gctggtaggc ttagaattaa agaatgtgat agacttcatg
     4681 caataaatgt tgagttaagt aaacttggag caaatataga ggagaaagag gatagtttga
     4741 taatcgaagg agtaagcaag ttaaatggtg gagtagaggt gtggagtcac aaagaccata
     4801 gaattgctat gacacttgca attgcttctt gtagatgtga taaaccaata atattaaaag
     4861 attttgagtg tgtatcaaaa tcttatccac atttttttaa agattttaag atgttaggag
     4921 gtcgaattga tgagtggaat atggggaaat aatttaaaag tatcaatttt tggagaatct
     4981 catggaaatg ctataggtat aaatatagat ggtcttcctt cggggattga acttgacctt
     5041 gataatattg ataaagaaat gaagagaaga gcacctggaa aaaattctat atctacttca
     5101 agaaatgaaa gtgatatacc agaaattcta agtggatatt ttaatggaag aactacagga
     5161 acgccattat gtgcaatcat aagaaatagt gatactcgtt caaaagatta tggagagctt
     5221 aaaaatttaa tgagaccagg acatgcagat ttcacaggta atgtgagata ttctggattt
     5281 aatgactata gagggggagg tcatttttca ggtaggataa cagctccatt agtattttgt
     5341 ggggctatat gtaaacaaat tttatcacaa aaaggaatag agataggagc acacataaaa
     5401 aaaattaaaa atatagaaga tatgagtttt gattatgtaa atatttcaaa acaacagtta
     5461 tcaaatttgc aaactttgga actaccttta cttgatttat caaaggaaga agccatgaaa
     5521 aatacgatta tagatgcaaa aaatcaagga gattcagttg gtggtataat tgagtgtgca
     5581 gtagtaggta ttaatgtagg gcttggaaat ccattttttg actctgttga atctacttta
     5641 tcacatttat tgttttctgt tcctgccgta aaaggtgtag agtttggttt aggttttgaa
     5701 cttgcagata tgtatggctc tcaaagtaat gatgaaatgt attatgaagg aaatcaagtt
     5761 aagagcaaaa caaataacaa tggaggaatt ataggaggga ttactactgg aatgccaata
     5821 attttcaaag tggcaattaa gccaactcca tcaattagca gacaacaaaa cacagttaat
     5881 ataaaagata aaaaggacga tattttatat attaaaggca gacatgaccc ttgtatagtt
     5941 caaagggcta tacctgtaat agaagcagta acagccattg gaatttttga tttgatgaaa
     6001 ggacgataat aatggaggat ttaacgagat atagaaatga gattgacaat atagataaag
     6061 agcttattca attatttgaa aagagaatga atacagttct tgaaattgcc agacataaaa
     6121 tgaaaaataa cactactata cttcaaaaag atagagaaga aaaagtacta agtagagctg
     6181 tagataattt agataataaa gcatattcac aagaaacggt acagtttttt aattctataa
     6241 tggaaattag tagaggatta caaaaaagat tgatagataa tgatggtgag cagaaaatcg
     6301 agtttggttt agattcatca aataagaaat ttgatttgtc aaatgtaaat aaatataagt
     6361 ctttaaaaga tgaattaaat aaaaaaaata tcctagtagg gtttcctgga aaatcaggtt
     6421 catttacaga agaagcacta aataaattct tcaacaaaaa aatatcaaaa aaacaattta
     6481 aagaatttga agatgttttc atagcactta aaaataaaga aataaactat ggaataatcc
     6541 ccatagaaaa ttcatctaca ggagctatct ctgaaactta tgaccttttg agaaagtacg
     6601 gtttttatat agttggagaa gaatgtataa aaatagacca aaatttaata gggataaaag
     6661 acacaaagct tgaagatata aaagaaatat attctcatcc acaaggtata ggacaatgta
     6721 gtgaattttt aaaacaaaat agtacatgga aattgatacc atttaataac acagcaacaa
     6781 gtgcagaact tgtaagaaaa cttcaagata aaacaaaagc agcaattgca agcaaaaaag
     6841 ctgcaagtat ttatggatta gaaataataa gtccttgtat aaatgatatt acaaacaact
     6901 atacaagatt tgtagtaatc agtaatcaaa tacacattga agaagaatca aacaaaatga
     6961 gtgtagtatt ttctgttgaa catgaagcag gaaaacttta taaagtactt ggatactttg
     7021 ctgaaaataa tataaatatg acaaaaatag aatcaagacc tatgaaaaat gcctcatgga
     7081 gatatttctt ttatatagat tttgagtgtt ctatatacaa tgctaaagtg tacgatttat
     7141 tagaattgat agaacataat acagcatatt ttaaatttat gggagtatat aaaaataaaa
     7201 ctgaatagat aagataaatt tttatttaat ttataattat taggaggtgt aagtatgaat
     7261 tttttcggtc tagtaggtga aaaactctct cacagtgttt cacctcaaat ccacaagaga
     7321 gtattcgaga tattgaatat tgaaagtgct tataaaaact ttgaaatttc aaaagaagat
     7381 atatctaagc tagacggtgc tataaaatta ttaggaatac aaggggtaaa tgttactgta
     7441 ccatataagg agcgtattat gaaatatctt gattttatat caccagaggc aaaacgtata
     7501 ggagcagtta atacaatttt actcagagaa aatatgttat atggttacaa tacagattac
     7561 tttggtcttg atagtatgtt taaaatggct aatattgatg ttcaaggaaa agtagcagtt
     7621 atattaggaa ctggaggtgc ttctaaagct gctcttacat attttattga ttctggtata
     7681 gaaaagcttt atgtttcaac tagaaaaaag gatgataaaa aattattaaa tagtaaagct
     7741 atattaatag attatgaaga acttaaacat ataaaaggag atataatatt aaatgctaca
     7801 ccagtaggta tgtaccctaa tgtaggaatt tcaccagtgt caaaatctat tatacaaaat
     7861 tttgatatat taatagattt aatttacaat cctggagaaa cagagttttt aagaattggt
     7921 aatagtatgg gtaaaaaaac ttgtgatgga ttatatatgc tggtagggca agcaataaaa
     7981 tctcaggaaa tttggcaaga tactaaaata gataatagta ttttagatgt tatatataat
     8041 gaactaaaat tagaattttt gtaagggaga ttgttatgat aaataaaaca aaagaaaaat
     8101 tgatattaat aggtatgcca ggtagtggaa aaactacaat tggtaaactt ttggccaaag
     8161 aatataattg tagtttctgt gatatggatg attatataat tcaaatatct caaaaaagta
     8221 tagcagagtt gttttcagaa ggagaagata tctttaggaa ctatgagact caagcatgta
     8281 gagaactttc tataagtgat aaaacagtga tatctacagg tggaggtgta ataaaaaagg
     8341 atgttaatat ggaaatacta aaagaaacag gtataataat ttttattgat agacctatac
     8401 aaaagatttt ggaagatata aatattaatt caagaccatt attaaaaaac ggaaaagata
     8461 gattgtataa tctttacaat gagagaataa atctttataa aaaattttca gatatagaga
     8521 ttttaaataa taaatcatta aataatgttg tatataatat tacaaatgca gtcagtgaaa
     8581 attttaaatt tgactttaaa gaaaaataat ctagggggaa gtaaaaataa tgaatattgt
     8641 tattgtagga ctaggagtta taggaggctc ttttgctaaa gcattaaaaa aagctggata
     8701 tgaaaatgta tttggagtag atgtagattt agaaacttta aaaaaagcag aaaaagcaaa
     8761 aatcataaaa aaaggatgta ctacaggtaa agagttattt aaaaaagctg atttaattat
     8821 actatctata tatcctagat tagttgtaga ttttctaaat aagaataaaa acttttttaa
     8881 aaaagggact ataattactg atactacagg aataaaagaa acacttatca atgatgtgtt
     8941 gcaaattatt ccagatgata tagattttat atttggacat ccaatggcag gtagggaaaa
     9001 aaagggtatt gattttgcaa gtgaacaagt ttttaatggt gcaaattata taattactcc
     9061 aactggcaga aacaacataa aaaatttaga gttagttgaa aatttaattt tagagattgg
     9121 atttaaaaga gtaaaaaagt taacttcaca aaaacatgat gagattatag cttttacttc
     9181 tcagttacct catgttatgg cagttgctct tataaatagt gatgaagaag gtagagatac
     9241 gggtaaattt attggagata gttatagaga tttaactaga attgcaaata tgaatgaaga
     9301 cttatggagt gaactttttt taggaaatag agataattta ctaaaagtta tagaaaactt
     9361 tgaatcagaa gtaaatttag taaaagaagc tatatttaac aatgataaaa ataaattaat
     9421 agagtatttt aaaaaatcat caataagaag agaagcttta gaaaaataaa tattaatatt
     9481 taagctatat atagatgggt ataaatataa gcgatagtgt atttaattgt attaataagt
     9541 atggattcaa tataattaaa tatgctattg atatatttgt acccttaact attgttatct
     9601 tttaaatgat aatgatattt atttaaatac tctttattaa caatttataa aacttaattg
     9661 taaaaaatac ttattaatag taaaataaag tgaatcaatt atattataat tgctaaagag
     9721 agtgaggtgt agctatttga aaaaaaatag attaatagca aagaatatat caatagcatt
     9781 tatagtacta ttctttttta gtgtatttac attcttttat gtaggtaata ttaatagagt
     9841 gttagaatat gaaacaaatg acataataac agttacaatt gctggatgga ttatactttc
     9901 atttttattt ttaggtatta taatttacat attatattca aaagcaaata gtcaaaaaac
     9961 tatagaaaaa gtagcatata cggattttgt aacaggttat tccaactgga gaaagtttga
    10021 attagatgtt acaaatttat taaagaaaac atcacaaaat aataaatatg caatggtcat
    10081 attcgatatt gataaattta aagcaattaa tgatatatat ggccataaaa agggaaattt
    10141 aatattaaaa gatattgcag atactttaaa tgaattgact gatatcaatg aaacttttgc
    10201 tcgtgtaagt gctgataatt tcaatatatt attaacatat aacaaaaaag aggatataat
    10261 aaatattatc aaaaagatta tggcaaataa tgaacttgta aacttatctt ttggaattta
    10321 tgaaatcaaa gataaggatt tatctgtaag tgtatatagt gatagagctt cacttgcaaa
    10381 atcatcaata aaaaataata gtgatgtaaa ttttgcattt tttaatgata aattaagaga
    10441 gaaattatta cttgaagata agatagaaaa agaaatggaa tatgctcttg aaagtgggca
    10501 attcgtaatg tatttacaac caaaatacaa tattaaatta gataaatttt gtggaagtga
    10561 agccctagtc agatggcaat atacagaaaa agaggtcata tatccaggtg attttattcc
    10621 tatatttgaa aaaaatggat ttattagaaa gattgatatg tacatattag aacaagcttg
    10681 taaagaaatc cggtctttat ttgataaagg aatttcacct ttacctatat ctgtaaactt
    10741 ctcaagagtt gattttttta aaaaagattt tattgaaaac atagtaaata tatgtgatag
    10801 atataaaata ccatatagtt taatagaaat tgaaattact gaatctagta tgtttggaga
    10861 tactgatact ctatttaatg ttagtagaaa cctacaggat attggcttta tagttgcaat
    10921 ggatgatttt ggctcgggat attcttctgt aaatatgctt aaaaatatac cattaaatgt
    10981 aataaaatta gatagaggat tttttgttga tgataaagat gttgataaga gtcaaattgt
    11041 tataaaaagc atagtttctc tcattaagca attaggaata agggttgttg ctgaaggaat
    11101 tgaaacaaga agtcaaatag aaatgttaaa aaaagcaaat tgtgatattg ttcaaggata
    11161 ttatttttca aaaccattac caattaaaga atttgaaaaa ttagtctata aaatatagtc
    11221 agcgagtctt aaatgggagg tggtgattaa gtgataagag caaaatcgtt aaaaaatgta
    11281 ctgagtattg ttttaatatt tttatttaca ataatttctt tttctgattt tgcatttaaa
    11341 actaatgtcc aggaagaaga aaatagtaaa attaatttaa gagaaatatc cctacaaagt
    11401 tccaatgcta taaaaataaa attagatagt tctctatcct ttattaaaag tgtggcaaat
    11461 atggtttctt attttaatac tatagataac tcaaaaatag ttccattatt agctaatata
    11521 tcaaaagaat ctgactttca aagaatctct attgtatctc ctgatggaat aagtcatacc
    11581 agtgatggca aaattatcaa tgtgtcaaag tatcagtatt ttaagaaagc tattaaagga
    11641 gaaagtaata tatctgaagt tgtgaaatct ccaattgatg gaaaagatac ttttgttata
    11701 gctactcctg tatttaataa gaataacaaa ataattggtg ttttatacgg ttcttactac
    11761 aatgataaat tagctgaatt tatagatata acaagtttta atagtgaagg gtacatagat
    11821 atatttgaat ctagtggtca atttgtttta aaatcttcac atacaaacaa actgattaag
    11881 tcaagtagta acatatatga tatatttaaa aaagcttctt ttgatgatgg ttatagctat
    11941 aaaaaaatat atgaagatac aaaaaataac aagagtggct ttacctcata tgaatacaaa
    12001 ggagaaaatc gttatgctac ttatacaccc attggtgtaa atgactggta tgtaatttct
    12061 gtgataccac aatatactgt aagaagaaac attgataaaa taaatcaatt agcattttct
    12121 cttattttca aggtattctt attgtttatt atgcttataa tatatattat ttataaaaac
    12181 aataaatctc agaaagatat actaaaagcc aacaaagaaa tctcatctat tacaaatagc
    12241 attcctggag gagtacaaaa gtgtaccctg ggtgaaacat gcaatattaa ttttttaagt
    12301 gatggattta tagagttgtt tggttataca agagaagaaa taaaaacatt gtttaataat
    12361 gatttttata gtttaataca taaagatgat gttgaaagaa taaaaaaaga aatttttaaa
    12421 caactttaca aaaataaaac tattgaatta gaatatagga ttataacaaa aaatggtaat
    12481 acagtatggg ttttagataa aggggagctt ataacagaac ctgatggaaa agaatatttt
    12541 tgttgtgtaa ctgtagatat tactagaaca aaacaattag aacaagagat ggaacaaaaa
    12601 aatctagaac ttgaaatgat atcagaaaat gttttaggtg gtataattat aacagaattt
    12661 aatgatgatt ttactataaa atacgctaac tctggttatc tttcaatgat tggatataca
    12721 cgtgaacaat tagaaaatga acttaaatac aaagcttgta atcttgtttt ttatgaggat
    12781 aaaaagaagg ctcttgaaag tatacaacat caattaaaca caaaaggaat agctgtatat
    12841 caacatagaa taagaagaag aaatggtaat attatttggg tttctataaa aggaaggctt
    12901 attattgatg atgatggtat tgaaaaaggt atttggattc taaatgatat aacagattta
    12961 aaaaatgcag aacaaaaact taaaataaat gaagaaagat ttagaattgc attaaagcaa
    13021 acatcaaaca ctatatttga gtatgatata aaaacaaagt cacttttaaa tactagtaaa
    13081 gagcttgata aatataatat ttataaaatt actaaaaacg ttccatattc tctagtagaa
    13141 tcaggagtta ttcataaaga ttttagtgat gattttataa acatgtatga aaatgtaata
    13201 aatggagcaa aaaaagcaag ttgtgtagtt aagatgaaac ttccagatga aaattatata
    13261 tggaataaag ttaccttgac tactattttt gatgaagatg gtaatcctgt aagagcaatt
    13321 ggtatacagg aagatataag caaacaaaag gaagcagaga taagatacaa tcaagaaggt
    13381 aagtatcatt cagctatatt gtcggaagca atgataacct atgaaataaa tgtatcaaag
    13441 gatactttta tcaaaggaaa tgaaagttgg caaaaaccat ttggaattaa gcctgacaat
    13501 aactattctc aaatggtaaa aactatagca aatagtattg tacataaaga caataaagaa
    13561 acatttttaa atacattttt atgtgaaaac ttattggatg catataaaaa taatgtgact
    13621 gaaataaaat tagaatatcg aagaatgaat caagaaaata aaatgatttg ggtcatttgt
    13681 acaatgcact taataaaaga ttctattacg aacgatataa aagcacttgc ttatgttaaa
    13741 gatattgaca agcaaaaaaa tgaagaaatt agattaaaat taaaagctga aagagatact
    13801 cttacaggat tatataataa aggtactaca gaaaaattga ttaatgattt cttgaactct
    13861 gaggaagcaa gcttaggaat gcatgcattt ttaattgttg atatagataa ttttaaatct
    13921 gtgaatgata atttaggaca tgtatttgga gataaagtat tatttgaagt ttctaaaaac
    13981 ctaaaaccta tatttagaaa agatgatata gtaggtagaa ttggtggaga tgaatttata
    14041 gtattcttaa aaaatattca gtcttttgag aatatcaaaa agaaagcaga aaaaatatgc
    14101 gatatattta gaaattctta tacggaaaat aaaaagacat ataaaatatc tggaacagtt
    14161 ggaatttcat ttgtaccaga acatggaact gtatttgaag aactttataa aaaagcagac
    14221 atagcacttt attatgcaaa gagcaaagga aaagataagt atgcacttta taatgattgt
    14281 atctaccaaa atgaacttga aaataatata agtgataata atataaaatt agcagataaa
    14341 tgtgagaaat ccaaaccagt acttaaagaa attcttgatt ctattgataa ttatatctat
    14401 atagtgaatc caagtactta tgaacttctt tttgtcaata ataaggtgtc tcgtttggat
    14461 ttagagataa aattaggaga aacctgttat aaatcactat taaaatctga gagaccatgt
    14521 aataattgcc ctcttaacgg attagaagaa aataagcatt caaaattcaa aatagagaca
    14581 aatacatttg gtaaaaatat cagtatagca agttggatta attgcataga tggagaatac
    14641 aactgtctta tagagtgtat agattcttct ttatacaaaa ataaataaaa aaggactatg
    14701 aagatatgtt aaatagtata actttgatac ttggtataat atttacaatt tactattttt
    14761 atctcaaaat agtttttgga ggaatttcat ttagtgagat tttcttagtt gtaggaattg
    14821 tactaattat ctatcaaata tttaagaaaa aaattaaaga aaagaaggtt ttttataggg
    14881 tgttaaaaat aataatcagc atttttttaa tagtatttgt agttactgag agtctaatta
    14941 ttttttatcc caaaaatagt ttagaatcaa aaagtgatta tctcttaatt ttaggagctt
    15001 ctgtaaaaaa gactacacca agtacaaccc tgaagggtag gttagacact gcattgaaat
    15061 acctaaaaat taatgataat tgttatgtgg tagtatctgg tggtaaagga agtggagaaa
    15121 aaataactga ggcaaaagct atgaaagatt atcttataaa aaatggtata gataaaaata
    15181 ggataataga agaggataaa tccacgaata cttatgagaa ttttaaatat tcaaaattga
    15241 agatagaaga acatagtcaa agaaaactaa gcgatttaaa agtaaaaata gtaacaacag
    15301 attttcatgt tctcagaagt aaaatattag catatagaaa tgaatataaa aatacgtctt
    15361 tttatgctag taaatcaaaa ctttcatttg taccaactta ctatacaaga gaattttttg
    15421 cattatggaa aacaatcatt tttgatagat aataaataaa aagactagat ataaactcat
    15481 atctagtctt ttctattccc ttaattctaa tccattttcc aactttactt gttgtagaaa
    15541 tttcaacatt gggatttaca agtaattgct tataagaagt tttatatttt acgattccaa
    15601 aatataattt tccttcataa tccattataa atccaaatgg tcttactctt ggtttattat
    15661 cttcaactgt agcaaaatag aatgttgagt tttcttttaa aaaattcatt attttttcat
    15721 gattaaatcc tctttgtatc ttatactaat ataatgaata taaat
//
LOCUS       DAEQAF010000085        15740 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.088, whole genome shotgun sequence.
ACCESSION   DAEQAF010000085 DAEQAF010000000
VERSION     DAEQAF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15740
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.088"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            278..1294
                     /gene="gap"
                     /locus_tag="KRN00_002853"
     CDS             278..1294
                     /gene="gap"
                     /locus_tag="KRN00_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH1828709.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            1689..2858
                     /locus_tag="KRN00_002854"
     CDS             1689..2858
                     /locus_tag="KRN00_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828710.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            3239..7492
                     /locus_tag="KRN00_002855"
     CDS             3239..7492
                     /locus_tag="KRN00_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBH1828711.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINLIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKAELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKNIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            7641..8135
                     /locus_tag="KRN00_002856"
     CDS             7641..8135
                     /locus_tag="KRN00_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBH1828712.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            8251..8628
                     /locus_tag="KRN00_002857"
     CDS             8251..8628
                     /locus_tag="KRN00_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBH1828713.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            8834..9274
                     /locus_tag="KRN00_002858"
     CDS             8834..9274
                     /locus_tag="KRN00_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBH1828714.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            9919..11226
                     /locus_tag="KRN00_002859"
     CDS             9919..11226
                     /locus_tag="KRN00_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828715.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYLDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLTSKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRKTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    11312..11574
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            11700..12503
                     /locus_tag="KRN00_002860"
     CDS             11700..12503
                     /locus_tag="KRN00_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1828716.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGDTVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            12541..13152
                     /locus_tag="KRN00_002861"
     CDS             12541..13152
                     /locus_tag="KRN00_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBH1828717.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            13184..13855
                     /locus_tag="KRN00_002862"
     CDS             13184..13855
                     /locus_tag="KRN00_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBH1828718.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            14154..14516
                     /locus_tag="KRN00_002863"
     CDS             14154..14516
                     /locus_tag="KRN00_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBH1828719.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            14952..15653
                     /locus_tag="KRN00_002864"
     CDS             14952..15653
                     /locus_tag="KRN00_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBH1828720.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
BASE COUNT         6380 a         1524 c         2763 g         5073 t
ORIGIN      
        1 attattttta aaaataagta tagtttaaaa attcaaaaaa aagatggcaa aatatgtccc
       61 aagggacatt gagtaaaata aatgatttca gcttatttac actaaaaagt acatactaaa
      121 tgaggggtaa aataaagaaa aatgatatac taattgtctt ttgataataa aaaaacatgg
      181 aatttgatta tttaatcaag aaaaagtatt gaacaaatga tttatttagt gtacaataat
      241 catgtaaaaa catagtaatg gagggagaca tttcataatg aaaattaagg taggaatgaa
      301 cggatttgga agaataggaa gagctgtatt aagaatagct caagaagaat taggagataa
      361 tatagaaatt gtagccataa atgcaagagc aacaacagaa tctttggcac atttatttac
      421 atatgattca tgctatggaa cttttagagg tgaagtagag gcaaaggatg aagacactct
      481 agtagtaaac tctaaagaga taaaaatatt aagatataat gacccagaag aattaccttg
      541 gaaagaattg ggggttgata tagtaataga atcaacagga ttatttacac aaagagaaaa
      601 ggcagaaaaa catattaaag caggagcaaa aaaagtaatt ataacagctc caggaaaaaa
      661 tgaagatata actatagtta tcggagttaa tgagaaagaa tatgataatg aaaagcacaa
      721 tataatttca aatgcatctt gtactacaaa ttgtctagct ccttttgcta aagtattgga
      781 cgaaaaattt ggtatagtaa aagggttaat gactacagta cattcatata ctaacgatca
      841 aagaatatta gataaaagcc ataaagattt gagaagagca agagcagcgg ctgaatctat
      901 aatacctacc actacaggag cagcaaaagc tgtgtcaaga gtactaccac aattagaagg
      961 aaaattaaat ggtttttcac ttagagtacc aacaccaaca gtttcacttg ttgatttagt
     1021 gtgcgaactt aaagaaaacg ttacatctga gcaagttaac tctgtgttaa aagatgctgc
     1081 tgaaggagaa ttaaaaggtg ttttaggata ttgtgacaag ccacttgttt ctatagatta
     1141 taaaggagat tcaagatcat ctattataga cgctctatcc acaatggtta tagaagacaa
     1201 tatggttaag gtagtttctt ggtatgataa tgaatgggga tattcttcaa gaactgttga
     1261 cttagtaaaa tatgtagctg aaaaattaaa ataatatata tttcttaaag caaattttaa
     1321 aaaaattttt taaaaaaatt atataaaact aaaaaaaaag attatgaaaa atattgaagg
     1381 aaaaattttt tcataatctt ttttctttca tgcaaaaaga tacaagttac aacttatatt
     1441 tgcatattag gtcgttagag aagtatatat atatttagta aggaatcata ctttttataa
     1501 aatgaaagat aagatgtcga aaacttgcat aaatctgaaa aatttttatt attaaaatac
     1561 tgattttcat tttaaaaatg ataaaaaaat gacaaataaa gttgcaaata gtaatactta
     1621 taagtataat taaaaaagag aaaaggtttt gttaaacttt ataacaaaaa aagaagggat
     1681 gattcaaaat ggagaagtta acagacagga gacaggttaa ggcagtaagc atggaaacct
     1741 tcattttcct aatattacta gtagttggtt ttgggtatgt tggtagtatt atgggagcag
     1801 gaatgatgtt caaagtaata atgagtacag cacatgcttt actattggag acagttttct
     1861 taattatggc tatggcagtt cttgcaggcg cattaagcgc actactttca gagtttggag
     1921 taatagcgtt aattaataaa attttcgctg tatttatgaa gcctttatat ggactacctg
     1981 gtgctagtat agcaggagct ataacaactt atttatcaga taatccagct attatacctt
     2041 ttgctaaaga taaaacattc acacagtatt ttaaacaata ccaagttcca gcattatgta
     2101 acttaggaac agcctttggt atgggactta tcttaacaac atttatgatt tctcaaggta
     2161 cagaatatgt acttccagca ttaattggta atttaggtgc aattataggt agtgtcataa
     2221 gtgttagaat aatgttgaca tttactaaga agttttataa atacaatccg gaagaagata
     2281 aagcaacagg aacattagag aaaaaggatg aatttagaga aatcagagaa ggaaatgtat
     2341 ttcaaagagc tttagatgca attcttgaag gtggtaaaat gggggtagat atgggaatgg
     2401 ctataattcc tggagtccta gtagtatgta cattggtgat gttattaact tttggaccat
     2461 ctacagaccc tgttacaggt caagaagttt atacaggagc tgcatatgaa ggaataaaat
     2521 tacttccagt tattggagat aaacttggat ttatattaga accattattt ggatttacat
     2581 caccagaggc aatagcattc cctataactt cattgggagc tgttggtgca gcaatgtctc
     2641 tagttccaga gtttataaag tcaggagcta taactcctaa tgatatagca gtatttacag
     2701 ctatgggtat gtgttggagt ggatatttaa gtacacatat tggtatgatg gatgcattaa
     2761 atgctagaca gttggcaggt aaagctattc tttctcatac aataggtggt ttatgtgcag
     2821 gagcagctgc tcactttata tttacactcg taggataaat gtaatcagct aagataaaaa
     2881 ataatataca aaaaaatggt tgttgatatg taataagaat ttacatatca acaaccattt
     2941 ttttctgact aaagataatt tataatacat aaacattaag tggatattag agttaagtta
     3001 tatttatgta aaaagtaaca aaaatctgta gaaatttatg acaaaattta gtacactaac
     3061 tatatgttct tatttaaaat ttaaggttag aattaggaat tacctagtag agtaagcttt
     3121 gattaataaa agaatcataa aataaaaata ttagtcataa agattataaa taacttactt
     3181 aaaataaagc catagaactt acaaaaatta aaaaagcata taaatatgga ggggtacaat
     3241 ggatgaatta tttcatatag gaattgatgt aggttctaca acggtgaagg ttgtggtact
     3301 taataatagt aataatatag ttcataaaga atatagaaga cattattctg atgtaaaaaa
     3361 atcagttaaa gaagtactaa atggtatata tgaaaaattg ggagatataa atactaccat
     3421 tataataact ggttcaggtg gaattggaat atcaaaaaaa ttaggtgtaa aatttgttca
     3481 ggaagttata tctagtacaa aatcaataga gtattttcat cctgaaactg atgttgtcat
     3541 agaacttgga ggtgaagatg caaagataac atatctaagt ggaggaatag accaaagaat
     3601 gaatggaata tgtgcaggtg gaactggagc attcatagac cagatggcat cacttttaaa
     3661 gacagatgcc agtggattaa atgaacttgc taaagggtat aatgttatat atcccatagc
     3721 ttcaagatgt ggtgtttttg ctaaaacaga tattcaacct cttataaatg atggagccaa
     3781 tcagactgat atagcaatga gtattttcaa tgcagttgtc gtacaaactg tgagtgtcct
     3841 ttcttgtgga agaaaaatag aaggaaatgt tgcgtttttg ggtggtccat tgtacttttt
     3901 atctgaactt agagaagcat ttaaaagagt attggattta aaagatgaaa acataatctt
     3961 cccagaaaat gcacaacttt atattgctat tggagcagga ttattatcag tagatgaaga
     4021 taatatacaa ctaaaatctc taatagaaaa attggatagt ataaagaata ttgaagatgg
     4081 agaagtaaat ttattagaac ctttatttaa agataaaaat gagtatgaag aattttcaag
     4141 aagacatgaa aaagaaaaaa taaattatgt ggacataaat ttaataaaaa gcaattgtta
     4201 tttaggaatt gatgcaggct caactacaac taaagcagca cttattgatg aggatggaag
     4261 acttgtatat tcttattata atagcaatga aggaaatcca ttaaaaacaa ccattaaagt
     4321 tataaatgaa gtatatgata tattaccaaa aaatattaaa atattgagtt caactgtaac
     4381 tggatatgga gaaggtctta ttaaaaaagc tcttaaaatc gataacggag agatagagac
     4441 tatagcacat tacaaagctg ctaaattttt caataaagat gtagatttta tacttgatat
     4501 tggtggtcaa gatatgaagt gcctaaaaat aaaagatgga gtaattgata atataatatt
     4561 aaatgaggct tgttcatcag gttgtggctc atttttagag acatttgcaa gttctttatc
     4621 tatgacaata gaagaatttg cacacgaagg tatttattct caaaatcctg tagatttagg
     4681 ttcaagatgt actgtattta tgaattctag agtaaaacaa gctcaaaaag aaggtgcaag
     4741 tgttggagat atatcagcag ggctatctta ttcagtaata aaaaatgctt tatttaaagt
     4801 aataaagatt agagatttaa atgagattgg taataatatt gttgtacaag gtggaacctt
     4861 ttataatgat ttggtgctta gaagctttga aaaactaatt ggaaaaaatg taattagacc
     4921 taatatttca ggaattatgg gagcttttgg ttcagcactt atagctaaag aaaaatatga
     4981 aagtggatac aaaacatcct tgttatctaa ggcagagttg aataatatca agctagaagc
     5041 aagtgtaact agatgtaaag gttgttcaaa tcattgtctt cttacaataa ataaattttc
     5101 tgataatgaa atttttattt caggtaatag atgtgagaag ggtgaagcta tttatggtga
     5161 taaaaaaata ggattagaaa agaaaaaacc aataaattta tttaagtaca aatacaatag
     5221 aatttttaga tacaaaccat tggaaaaaga agaagcaaaa aatggggaaa tagggatacc
     5281 aagagtattg aatatgtatg aagattatcc attttggttt acttttttca atgctatggg
     5341 ctttagagtt gtactttcag ataggtcatc aaaacagtta tatgaaactg gtataactag
     5401 tattgcatct gaaacagttt gttatccagg aaaattagtt catggacata tagaaaattt
     5461 aattgcaaaa ggtataaaaa atatatttta tccaagtgta acaaatgaaa ataaagagga
     5521 ttcaaatgca gataattatt ataattgtcc tgttgtaata tcatattctg aagtaataaa
     5581 aaacaatgta gagaatataa gaaataagaa cataaattat ataaatccat ttataagtct
     5641 aaatgataag gaaaaattga agaaaagact atatgatgaa ttatcaagac atttttctga
     5701 tataaaaata actaaagaag aagttaatca tgcagttgat aaagctactg atgaacagaa
     5761 tttatttaaa atggagatac aagcagcagg tgaaagagca cttaaagaaa taaaagaaag
     5821 aaatatgaag gggattgtgt tatgtggaag accatatcat atagacccag aaataaatca
     5881 tggaatgcca gagcttataa attcattaga tatggcagtg cttactgaag actctatatg
     5941 tcatttagcc aatgtacaaa gaccacttag agttgtagac caatgggtat atcattcaag
     6001 attgtataaa gcagctagtt ttgtaagaga taaaaactat ttggaacttg ttcaacttaa
     6061 ttcatttggc tgtggattag atgcagtaac tacagaccag gttcaagaaa tacttaatga
     6121 aaaatcgaag atatatacta ttataaagat tgacgaaggc aacaatttag gagcagctaa
     6181 gataaggatg aggtccttaa aagcagctat gtttgagaga gaaagcaaaa atatagatgt
     6241 aaaaaatata aaggtaaaca ggatacagta tgctaaaaat aatcagataa cgaacaaaca
     6301 tactatatta gcaccacaaa tgtctccaat acatttccaa ttccttgaaa aagctgttaa
     6361 cttaagtggt tataatatag aaattctaaa agatactgat agtagtgtaa ttgaagaagg
     6421 gttaagatat gtaaataatg atgcatgtta tccagctata atagttgtag gtcagctaat
     6481 aacagcatta aaatctggca aatatgattt aaataacact tctgttacta taactcagac
     6541 tggtggaggt tgtagagcta caaattatat tggattctta agaaaggcta tatatgatgc
     6601 tggatttaaa gatgttcctg tcattgcact tagtgtaaat ggaatagaag atagtggtat
     6661 aatggataat atatcactaa aattaatcaa tagactcttt atgtctgttg tttatggtga
     6721 tttgctgatg aaagtactat atagagtaag accatatgaa aaagttactg gaagtgcaaa
     6781 tgctctatat gaaaaatggg ttgatatatg caaatcttct cttgttaaag caaaaatttc
     6841 tgtatttact agaaatataa aaaatatagt aaaagaattt gataatttag agatactaga
     6901 tatcaaaaaa ccaaaagtag gtttggttgg agaaatattg gtgaaattcc atccaattgc
     6961 aaataataat ttagtagata tattagagcg agaaggtgct gaagcagtcg tgccagacct
     7021 tacaaatttc ttcttaagtt gtgcctttaa tactatatac aaacacactc atttagaagg
     7081 aagtagaaag agtagaatga taggagaagc atttatatac ataactggaa tatatcaaag
     7141 agtatataaa aaagcacttg ataagagtga gagattttat gctccagcca atataaaaaa
     7201 tgttgctaaa agtacagaac cagtagtgtc attaggtaat caaactggag aaggttggct
     7261 tttaacaggt gagatggttg aattattaaa tgaaggtgta gaaaacatta tttgtatgca
     7321 accttttgga tgtttaccta atcacataat tggtaagggt tctataaaag aattaaagag
     7381 gttgtataaa aatgcaaata taatacctat tgattatgac ccttctgcaa gtgaggtaaa
     7441 tcaacttaac aggataaaac ttatgctttc taaggctttt aaaaatatat aagatttata
     7501 ttttgatatg ttaaaagtta atgaatttaa aaatatactc tatattaagt atctataaaa
     7561 aagagttatc ctatttttta gggtaactct ttattagtta aaaaattata tgtatactga
     7621 tattaaaggg gggaagtaat atgagtttag tatatgatgt ttataaatca aaattaggaa
     7681 atttgtacat attaagtgaa gatggtttta tagttagtat atacatagga gatgaaaaat
     7741 ttaataattt aaaaaatgaa tgtattaaaa aaggaattga tataaagaga agtaaggaag
     7801 atttaaagga agcaataagc cagatagatg attactttaa tggaaaaaga aaagtcttta
     7861 atttaaatat tcgtattgaa gggactgaat ttcaaaaatc agtttatagg gaaatgttaa
     7921 aaatacctta tggagaaaca ttgtgttatt cagatatagc aagaaatata aacaatccaa
     7981 aatcagtaag agcaatagga caagcaagta aaagtaataa aattccaata ataatacctt
     8041 gtcatagagt agttggcaaa aaagatattg gtggatatat ggggaatcat tctgatttga
     8101 aagagatact attaaattta gaaagacaga gttaacttag aaagaaatgt ttttattgtt
     8161 aatatttgat ataataatag taaaaagaag tattttttac aaaaataata aggaatttat
     8221 tttaatttac aaaaatgagg ggggatttta atgtgtgata aagttatagc atcaaaatat
     8281 catgagaagg gatttaattg tgcagaatca gttataaaag catataatga ggaatttaat
     8341 acagatatac cagtttgttt aggaagtgga ctgggttcag ggtgtggggt tgctagttta
     8401 tgtggtgcag taaatgcatc aaatataata attggatatg taaaaggcag aaaccacgaa
     8461 gatgaaagta ctaaagctaa agtatatgct aaagatttaa ctacaacagt aagaaaagag
     8521 tatggttcag agttatgtat agacctaaaa aaagatttag ttgcttgtag agaaataatg
     8581 gatttcgcat atgatagtct aaaggaaact ttaaaaaaag aattataaga aaataagcta
     8641 tcaaatataa attatttgat agcttatttt tatagccgat actaaataaa tcaaatatat
     8701 tttagaatta ttatttgtaa ataaacagca aataatttta ggctttttat ttaatatagt
     8761 ttttatttat atttagtttt gaatatgtta tactttgttt aaataaatat ttgtaatgag
     8821 ggagatgaga agattgaaga atctcaattt acttattaat aaattatatt caaaaaatca
     8881 taatgaagca tataaaactt ttttattctt agaaaatgaa agtttaaaat caaatattac
     8941 atattgtttt tttgactcat tcctagaaat gattgataac gaaaactcat atattcgaac
     9001 aaggggattg ttattaatct ctgcaaatgc tcagtgggat attgataata aaattgaaat
     9061 aaatatagat agtatactaa gtcatatcgt agataaaaaa ccttctgtat caagaatgtt
     9121 tattaaatcc atacctaata ttacaaagta taaagaaaat cttattaatc gcataaaaat
     9181 ggaattaagt aatgcagata taagtattta taataataat atgaaaccat tagtagaaaa
     9241 ggatataaac gatacattat ctaatattag ttaaatatta atatagaaat tgaatattat
     9301 ctagttacaa ttatttataa ctaagataat aaaacaacaa tggtgctaat ttatatgtat
     9361 aaattaatta tgaaaaattt atataagtaa aatatattaa cataaaggta aaattttgta
     9421 tactaaaagg gaatatttac agtttaatgg cagttttaaa ataataaatt aaagctgtca
     9481 tttttattta aaaattttta gaaaaagtac aatagtgtta atgtgtgaat tagataaggt
     9541 gtatataata gtttagatga tatgatataa aatatgttgt aaattaaatg ttttctttga
     9601 caatatatac acaaggatga taatatctat atgaataaaa gatagtgtgt aatttgataa
     9661 tatgtaatta taacattatg atataattac aataaagtat gtaataatct gtagaaattt
     9721 caagctagtt atctaagttt tcggataact aaatctaaac ggaatacata atgtattaaa
     9781 taaatgatga tactaaaatg atactatttt tatagaaatt tattgaggta tataattaat
     9841 gaaaataata tattaaatta tataaattaa attatataat atattgagtt ttacataaaa
     9901 gcaaaggtgg gaataaaaat gaaagaaatt gctgatgcta taacatcaga gtatttaagc
     9961 tatggtatca atgaagatat tagtatctat gaaggtagat tttgcatata tttagataaa
    10021 aaatatagat gtaatgggaa aatttattat aaaatgacac ctccaatatc tataagtttt
    10081 aaagcagaca taggttgtgt tgaagagata gacaatgaag atgacaattt agctttagat
    10141 tatgataatg ctattcttga agttcatgga tataaaatta tttctataac aataaatact
    10201 ttaagtgaat ttagtgtaga aggttatatc aatgatgact gcataaaatc taagaactcc
    10261 tatgttgaat atttagattt taatataata aacttagata aaatacctgg aaaactcatt
    10321 aaatacaatg ataaggtata cgcaggtaga attgaatttg atataaatga ttatgttgta
    10381 actatagaca agcgatatga ttatagaaaa gaattaaaat cagaattaaa gtctaaatct
    10441 ggagcaataa taactcatat aggtaggatt agaagaaaag atggtagaat ttttagaaca
    10501 aataatacaa taaatctttt agataggata tcaacagctt tgagttttat gtgtggaaga
    10561 tatgtagggt tttgtttggc caaagggtat agaagtggta atgaagttta tagaatatgg
    10621 aatgaaaatc aaatatctcc ttttagatat gtaccaacat ggtcagatac actttcaaat
    10681 tatcataata tggaaaaata tataagcctt atgtgtaaaa agctagaaga tttttattat
    10741 ggttctgcta taaagagtgt tgttgattgg tacatagaat ctcttggaag tgctaccatg
    10801 gaaaacaata taatatctgt acaaattgca cttgaaactt tgtcatatgt aattctagtg
    10861 gaacaaaata agatacttac agatgaagca tttgactgta atttgacatc taaaaatata
    10921 agactcttac ttgatacatg taagatacca tatggtaaac atgaattaaa tatatttgat
    10981 aatataataa aaaataaatt tgatgatgga gtggatttag tcatttattt aagaaatagc
    11041 atagttcatc caagtagaaa gactcataga gctgtgttag aggttgaaga tatttggaat
    11101 ataatttcaa taggaacgag atatattgaa cttgttttac tctttatttt aggttataga
    11161 ggagaatatt caaacagatt agtagaaagg tgttatggtg aagtggaagt tgtaccttgg
    11221 aactagattt ttatatttat tttaaaatat atattgacat atattgcctt atgctataaa
    11281 atcaatatta taataataat tcagaataac attaaatgct aagaaaagaa atagtaaaag
    11341 tagttaatct taaacagaga gtttccgatt ggtgagagga gcaatagatt ttactttgaa
    11401 cacatctttg agcaggactc tgaaagagta gaaatacttt attaggagat ttccggaatc
    11461 cttgcacccg ttatagtgct agagtataat aattttattg tacttaaaga ggttagtgtc
    11521 gtgaggcatt aatgaacaga ggtggaacca cgagagttaa ctcccgtcct ctagcagaag
    11581 ctagaggcgg gagtttttta atataatttt ttaagcgcgc agagaattat attgcaatag
    11641 atacactttt taaaaaataa tcaaaatatt ttaaaaatta aaagacgagg gagaatatta
    11701 tgaaaaatat attaaaaaaa gtaggaatat ttacaattat gttaggttta ttaggtggag
    11761 ttgtaggttg ttcaaaacca gataatgaaa aagataagga tgcttcaaag gaatctaaaa
    11821 aagaagtagt tgtagggttt gataatacgt ttgtaccaat gggattttta gatgaaaagg
    11881 gagatacagt aggatttgac gtagacttag ctaaagaaac atttaaaaga cttggaatgg
    11941 aagttaagtt tcagcctata gattggtcaa tgaaggaaac tgaattaaat gattcaaaaa
    12001 ctgtagatgt attatggaat ggatattcta taacagacga aagaaagaaa atagtatcat
    12061 atacagaacc atatttacaa aataaacaga taatagttac tctaagtgac tcaaaaataa
    12121 attcaaaagc tgatttaaaa gataaagaag ttggaacaca acaaggttca acagcacttg
    12181 atgcagtgga aaaggataaa gattttatga atagcttaaa aggtggagca ccagttcttt
    12241 atgatactta tgataaagca cttagagatt tagagatagg tagaactagt gcagttgttg
    12301 gtgatgaagt tttaattaga tactatatgg gacaaaaggg tgaagacaaa tacaaggtat
    12361 taaaagacga ttttggatta gaagattatg ttgtagcaac ttctaaagaa aatccagaac
    12421 tttgtgagaa aataaatgaa acattaaaag aaatgaaaaa agatggaact tttgacaaga
    12481 tttatgataa gtggtttaaa tagaagataa gttagctgtt aagaaggggg cactaaaggc
    12541 atgttacaag gtttagagat agttatagca atgttttgta taacattgat agtatcaatt
    12601 ccattgggga ttggagttgc atttttaaga ttatcaaaga ataaattagt aagtggtatt
    12661 acacaatgtt atatattgat aatgagaggt acacctttac ttttgcaaat gatagtcata
    12721 ttttacggat tacctctttt aggaattgta tttgacagat ttacagctgg agtagtagct
    12781 ttcttcttaa attatgcagc atattttgca gaaatattta gaggtggaat acagtcaatc
    12841 gatagaggac aatatgaagc ttcaaaagta ctaggatttg ataagtttac tatgtataag
    12901 agagtaatct ttccacaagt ttttaaaaga atactagcac ctatttcaaa tgaagtaatc
    12961 acattagtaa aagatacatc tttagtatat atattaggat taaatgatat tttaagaata
    13021 tctcaaatag caatgaacag ggaagcaagt ctgttaccat tatttgaggc aggagcgata
    13081 tatcttatat ttgtagctat acttactaag ggatttgaat tacttgaaaa aaaatattct
    13141 tattatagat aaagttacaa tattatagga ggaggttttt tatatgttga aaatcaaaaa
    13201 cttaaataaa tcatttaaaa aaaatagagt acttaaagat atttcttttg agttagaaga
    13261 aggtcagatt ggagttttac ttggtaagtc tggtgcagga aagaccacaa tattaaggtg
    13321 tataaatggt cttgaagaat ttgatagtgg agagattata atagataatg aggtaataaa
    13381 aaataagaga gatatggcaa aaatacgagg aaaaataggt atggtttttc aaaatttcaa
    13441 cttatttcct catatgacag tccttgaaaa tataattgaa tccccagtta atgtttttaa
    13501 agttcctaga aaagaggctg aagagagggc tagagaactt ttaagattag ttgatttaga
    13561 agataaatta aattcttatc catttgaatt gtcaggagga cagcaacaga gagttgctat
    13621 agctaggtca tgtgcattga tgccaaaagt cctttgtttt gatgaaccta cttctgcact
    13681 tgatattgat actattcaaa gagtagtcaa tataatgaac agacttaaag acaaaggtat
    13741 gacaatatta ataattacac atgatgttgt cttctcaaat aatgttgcag ataaaattat
    13801 aagtataaaa gatggtatag tagaaaatgt tcaaataaaa gaaaaaattg tttagagttt
    13861 tataaatata aactagggta gaattttata atataaataa agggcaagta aaatcaaata
    13921 tactatgccc ttttgttatc tcaaaattta atcttatatt ttatgtttaa gttacattat
    13981 aatttataat aaaaataaaa ggactattta aatatataat gtgaataaat gtttaataat
    14041 ttgaaatatg ataatttttt atgttgaaag cttataatga ttatgatata aattggttat
    14101 agtatacaat ttatgggtat aacaataaaa aattagaaag gaatttttat aaaatgatta
    14161 aattatatgg atatacaaaa tgctctactg ttaaaaaagc taaaaattgg cttaaggaaa
    14221 ataatttaga atttgaagat atagatatgg ttcaaaaccc tcctagtaaa gaggagttaa
    14281 aatcaattta taagactagt ggatatgata taaagaaatt ttttaataca agtggtatga
    14341 aatatagaga attgggtctt aaagatattg taaaaactga atctgatgat aaacttttag
    14401 aaatattggt aagtgatggt atgcttatta aaagaccatt acttttggat ggtaaaaatg
    14461 tattattggg ctttaaagaa gatgtatgga aaagtacttt gctaaaagaa gattaggaag
    14521 agataggtgt gttgattaaa attattaatt aatacaccta taaatttatg tattaaatct
    14581 aatttttata aatattaatt agcaaattca aatcaaaaaa attcatatca acaaacatat
    14641 tacttcttat tacaaattat atcatatgtt ttatattaaa atattataat attacaacga
    14701 attgttacaa aattacttat tattaaccat gaacatttgt tttgtgctat catatttata
    14761 taagggaatt gtcataaaaa atatcttgtt catacagttt tatatagaaa aaagaaatga
    14821 atcttttctt tatataagta tattttgtaa attgcctcta tatttatagt ttaaataata
    14881 gtggtattaa aaatctgaca acaaaaataa aactttcaaa aaattaaatc taaaaagaat
    14941 aggagataaa tatgagtatt gaagatttat atgattttga atgtgttcct ttgaacaatg
    15001 agattgatat tgatgtttta tttgaaaaga tgatagaaga tggaaaagaa aaagaatata
    15061 caccaattat agtcattgat gaaaaagtag ggctattaag aaaaaatata gatatgatta
    15121 ctaaagagta tggttctctt gaaaactata gagagtattg tttaacaaaa tataatgaaa
    15181 ttgatgtaaa tcaatttttt gattttagga agagtgagat ttcagaatta ttaaaggagc
    15241 taattgattt agaagatgat ttttatgatt ataaacattt tagacccatt atgaatatag
    15301 atatatttca tgaatataac aaagtttaca tagctaaaat tccaacaatt aaaccatatg
    15361 aagtatttgc atacatacct attggcggat ttaatgattg tcctagagat gaagaacata
    15421 tagctattgc aaaatattgg tatgaaaagc atggaatctt tccaatcgca attggatgtg
    15481 atacagttca atattctgta aaaaatttaa ctaaagatgg taaaaaattt gatgacttat
    15541 gtattgaatt agtattttat tgtgaggata ttattataca agggtatgaa accttaaagg
    15601 ctcttaagga tgtattaaaa cgctctacaa tagtgctttt ttggtgggat tgatattcta
    15661 tcatttagat agtattaaat tgttagtcac caagaatcca cttgctttag ttatggggag
    15721 tgtgtcaaac taggttttta
//
LOCUS       DAEQAF010000086        15609 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.089, whole genome shotgun sequence.
ACCESSION   DAEQAF010000086 DAEQAF010000000
VERSION     DAEQAF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.089"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            50..868
                     /gene="larE"
                     /locus_tag="KRN00_002865"
     CDS             50..868
                     /gene="larE"
                     /locus_tag="KRN00_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBH1828721.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            923..2071
                     /locus_tag="KRN00_002866"
     CDS             923..2071
                     /locus_tag="KRN00_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBH1828722.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRTLDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            2207..3595
                     /locus_tag="KRN00_002867"
     CDS             2207..3595
                     /locus_tag="KRN00_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1828723.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSVGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            3624..4322
                     /locus_tag="KRN00_002868"
     CDS             3624..4322
                     /locus_tag="KRN00_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828724.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            4325..5758
                     /locus_tag="KRN00_002869"
     CDS             4325..5758
                     /locus_tag="KRN00_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828725.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            5780..6517
                     /gene="truA"
                     /locus_tag="KRN00_002870"
     CDS             5780..6517
                     /gene="truA"
                     /locus_tag="KRN00_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBH1828726.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    6628..6835
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            7088..8287
                     /locus_tag="KRN00_002871"
     CDS             7088..8287
                     /locus_tag="KRN00_002871"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBH1828727.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            8534..9580
                     /locus_tag="KRN00_002872"
     CDS             8534..9580
                     /locus_tag="KRN00_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBH1828728.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            9688..10851
                     /locus_tag="KRN00_002873"
     CDS             9688..10851
                     /locus_tag="KRN00_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1828729.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     NRNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSNYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(10940..11320)
                     /locus_tag="KRN00_002874"
     CDS             complement(10940..11320)
                     /locus_tag="KRN00_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBH1828730.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(11323..11982)
                     /locus_tag="KRN00_002875"
     CDS             complement(11323..11982)
                     /locus_tag="KRN00_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBH1828731.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(12088..13062)
                     /locus_tag="KRN00_002876"
     CDS             complement(12088..13062)
                     /locus_tag="KRN00_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1828732.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGILVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDITGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVEGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKIINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(13102..13449)
                     /locus_tag="KRN00_002877"
     CDS             complement(13102..13449)
                     /locus_tag="KRN00_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828733.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(13666..14622)
                     /locus_tag="KRN00_002878"
     CDS             complement(13666..14622)
                     /locus_tag="KRN00_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBH1828734.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            15065..15433
                     /locus_tag="KRN00_002879"
     CDS             15065..15433
                     /locus_tag="KRN00_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBH1828735.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
BASE COUNT         6148 a         1662 c         2536 g         5263 t
ORIGIN      
        1 agaatgtaaa aaaataatat atagttttat agttcatatt tttccagata tggaggtaaa
       61 ttttgtgaag gaaaaagaaa aattagataa attaaaaaaa atgttacttg aattaggcag
      121 tgttgtagtt gcttattctg gtggagtaga tagtaatttt ttgcttaagg ttgcaaaaga
      181 tacattaggt gaaaatgtta tagctgtgac tattcatgca atgatgcatt caagtaggga
      241 aattgaagag gctaaacaat atactcaaaa ttttggtgtt aaacatatca tattaaatat
      301 agaaaacttt gatttaaaag aatttaaaga aaatggtgtt gatagatgtt atcattgtaa
      361 aaaatatata ttctctaaaa taaaagaggt agcaaaagaa cataatataa agtacatagt
      421 agatggaaca aatatagatg atttaggaga ctatagacct gggcttaagg cattgagtga
      481 attaggagta attagtccat taaaagatag tagtttaaaa aaagaagaaa ttaggtcgct
      541 ttcaaaaaca ttaggattaa atacttttaa taaaccatca tttgcatgtc ttgcgagtag
      601 gataccttat ggagttgaaa taacagatga aaatttaaga atagtagaaa agagtgaaga
      661 atatctatcc aatttaggtt tttctcaatt tagagtgaga atgcatggag atatagctag
      721 aatagaagtt ggacaggaag aactaggtaa attttttgaa aataacaatt ttaataaagt
      781 tgatactaaa ttaaaaatat ttggctttaa atatgttaca ctagatatgt caggatataa
      841 aatgggaagt atgaatttaa atgtgtagat tattttaaaa ataaataagt tttatagtta
      901 atataaggaa acaggaggtt ttatgaaaaa ttatacgtta atatcgccat gtttttttgg
      961 aatggaaaaa atgctggcta gagagattac taatttagga tatgaaataa taaaaacaga
     1021 agatggaaga ataacatata aaactgatga gtttggaata gcaaagtcaa acatgtggtt
     1081 gagatgtgct gaaagagtac atcttaaaat tgctgaattt gaggcaaaaa gctttgatga
     1141 attatttgaa aatacaaaaa gaataaactg gtctagatat ataccttatg gagctcaatt
     1201 tcctatatca aaagcttcct ctataaaatc aaaattatac agtacaccag atgtacaagc
     1261 catagtaaaa aaggctatag tagaaagctt aaagaaaagt tatttggagg atggtttgct
     1321 taaagaagat aaggagaaat accctatttt tgtatttata cacaaagata aagtaaccat
     1381 ttctatagat acaacaggag atgctttgca taagagagga tatagagaaa aggcaaataa
     1441 agctccaata agagagactt tagctgctgg gcttatttat ttaactccct ggaaagcagg
     1501 tagagtttta gtagacccta tgtgtggttc tggtactata ttgattgaag ctgctatgat
     1561 tggtataaat atggcacctg gcttaaatag agagtttata tcagaaaagt ggagaactct
     1621 tgataagaaa atatggtggg atgtaagaaa agatgctttt aataagatag ataatgaatc
     1681 taaatttaag atttatggat atgatataga tgaagaatct atagatatag ctagagaaaa
     1741 tgctgaaata gcaggtgtag atgaatatat agagtttaat gtaggagatg caactcaatt
     1801 taaaagtgaa gatgagtttg gatttataat cactaatcct ccttacggag aaagattaga
     1861 agataaagac agtgttaaac agttgtataa ggagcttggt tatgcattta gaaaattaaa
     1921 aaattggtcg tattatttga taacttctta tgaagacttt gaatatgagt ttgggcaaaa
     1981 agcagacaaa aaaagaaaat tgtataatgg tatgttaaaa actaactttt tccaatatcc
     2041 gggtcctaag cctcctagaa ataataaata agttttacat gatttatttg taaaatataa
     2101 aattttatta aaataagtaa aacattatga tgccttgaaa cgtctaatta ttgtgaggag
     2161 atttttgtga acaaatttaa aaatttatag gattaggagg agttaaatga aagtgttaaa
     2221 gcttattact gtagtagccc tgatgatgtt atttgttact ggatgtaata taaaaactga
     2281 atctccagaa caattagcga agatacctga ctatgatgat acaaaaaaag tattgtatga
     2341 tggtattgac cagttactaa aaccagattc atctatgata ttgccttcta atacaaaaga
     2401 agtaggaaaa ataaataagg tagatttaaa cagcgatgga attgatgaat tagtagtatt
     2461 tgaacaaaaa gaagatttaa gtaataatgt gagtcaggta gggtttgtaa ccttgagtta
     2521 caatggagaa aaatacgtac ttggagacca ttttttagaa aatggcgaat caatagaata
     2581 tgctaatttt tatgatttgg actcagatgg atataaggaa gttatcttat tggttaaatc
     2641 caaagacaaa actaatatgc atatatataa agtagtagat aatgaaataa caaaaatata
     2701 tgacttggat gcatcatggc ttcaaaataa agaagatttt aatgatatga aagtaaaaat
     2761 tggatatata gatggagatg acaagttaga catattgatg cttcatttga ataataagac
     2821 taatgaaatg tttgcaagtg ttgcaaattt tgatgggaaa atgaaaatca aagattctgt
     2881 taagtttgaa aatgtaaaaa acttaagtga attatatata acattaggta atgttgcttc
     2941 atctgttgga aattcttctg cagctataaa aggtattgta cttgatattc ctatattgaa
     3001 agataataac tatattacgc agatacttta tatgaaagat gggaaaatta acaaagcttt
     3061 tagtgattat gataaaacta ttactaaatc ttattatata cctgtagatg atattgacaa
     3121 agataagatt atagaaatac ctatagttgc aggcagtaca ggtaataata aaaatactta
     3181 tagttctaaa tcatctgcaa ctataagttg gtatagatgg aatggaaaag aaggtgctga
     3241 ctcaagttta atatttacaa gtcagatata ttataattat aaatataatt ttaaattatt
     3301 tattccaaat aatttatttg ataaaatact tgttgaacag gaatttgttg gagaaaaagc
     3361 agtatttaaa ttttactatt ttgactattc agaccgtaag aatttattta atatagtagt
     3421 agagagtaaa aataaacttg aagatagaaa aaatacaggt actcaaaatt ctattgtact
     3481 tcaagagagc gatgaatata ctttcttact agttgtaaac aatgcaaatg aaatggataa
     3541 gctagatatg actatagacg cattaaaaga atatttctca ttaatatatg gttaatatta
     3601 tactcaattg gaggttttat tttatgaagg aaaagatact tatactagaa gatgaaattg
     3661 gtattagaag ttttgttagt ataaacttaa aaagggaagg ctatgaaata gttgaggcag
     3721 gtactggaag agaagctata gaaaaaatga caacagaaaa ggatattaca atagctcttt
     3781 tagatgtaat gcttccagat ataagtggta tagaagtatg taaatttata agggagaatt
     3841 ttgaccaagt aggtataata atgcttactg ctaaagctca agaagatgat aaaatagaag
     3901 gatttatctc aggagcagat gattacatca taaaaccatt tagtataaaa gagcttttag
     3961 tcagagtttc tgctcttctt agaagagtag caaaggatga ttcaagtgtt aagtcgagtg
     4021 agatagtttc tccaccattt atacttgata tagacaaaag aaaattattt aaaaatggaa
     4081 aggaaattga gcttacacca actgaatttt caatagtgaa atatctaata tcaaatgcta
     4141 agcagtcgtt aagtagagac cagatattag acgaagtatg gggaactaac tatttatatg
     4201 attttaaaat agtagatgta aatataagaa ggataagaaa taaaatagaa gatgacccat
     4261 caaaaccaaa atatatacaa actatttggg gttatggata ctgttttaga aaggaagaat
     4321 aatagtgtta cattttgaag gtctgagaaa aaaagtaata aaaaactatt ttataataat
     4381 tattataatg gttactctgt ttgaaggatt gttcatgttt tacatacaaa actactatta
     4441 tgattctgtc aaacagctac ttgaatctga aataaaatat gctgatgaat ataatgctat
     4501 tacaatggaa actacaagtt ttgagaaaaa agtaaaaaat atatttgata aacaaccctt
     4561 aactaaaaat tcagaatttg gaatttcaat aatagataaa gataaaaata ttatattaga
     4621 ccaatatggt tttaaaagta aagaaaaagc aaactatgaa gatgttaaca atgcattaaa
     4681 agatataaaa actaaaaatt taacacctta tacttataga ataccagata caggagagca
     4741 tgttatgagt atctccttac cacttaaggt aaataatata atagaaggtg ttgttagata
     4801 tacagtatca ttagatgcta ttgataatgc aatattaaag caagctacat ggcttatatt
     4861 agcaggaata tttatactta ttatagctat actaataagt cttaaatttg ctgagactct
     4921 tataaaacca ttacgagagc taaagaaatt tgcaaatgaa ttggctgtag gaaattataa
     4981 tataaaatta gaaaagatga agattgtaga tgatgaaatt ggtgatttag cacagacatt
     5041 tgaacacatg gcacatgaga ttgacaaaag tgaaaaatta aaagaggaat ttatatcatc
     5101 tgtatctcat gaactaagga ctcctcttac atctataaag gggtggagtg aaaccttagg
     5161 ttatgaaagt ataacaagag aagaactaga cttaggttta ggcattatac aagatgaaac
     5221 agaaagactt ataaaactag ttgaagaatt gttagacttt tcaaggcttt cttcagacag
     5281 gataaaactt catgttgata tagttgatgt tgaaggttta attgtaggtg ttgtaaatca
     5341 acttaaagtt aaagcagctg aaaaagatat atcactttta tttgaatttg aaaatgaatt
     5401 tatagagaac attcaaggag ataaaaatag attaagacag gttctcataa atttaataca
     5461 aaattcattt aaatttacga gtcaaggtgg ttacataaaa gttgtagctt ctcaagatga
     5521 agagataaca accatatcag tagaggataa tggttcaggt atagaaaagc aaaatttaaa
     5581 taaagtgtta gataaatttt tccaagaaga ttataataag gctggtagtg gattaggact
     5641 agcaattagt aatgaaattg taaaacttca tggtggaaga atgaaaatag aaagtgaaaa
     5701 gaatgttgga acaaaaataa cttttaatat aaaaaataaa tttgctaaac aagcataaat
     5761 tcttagaaag aggattaaga tgagaaacat aaaaatgata gtagcatacg atggttcaag
     5821 atataaagga tatcaaaaat taggtgacaa taatatgact attcaagaaa aacttgaaaa
     5881 tgttttaagt aaaatgacta atgaaacagt ggagataata ggttctggaa gaactgatat
     5941 gggagctcat gcaagaggac aagtggtaaa ttttagaact aattgtatgg attctttgga
     6001 taaaattcaa aaatatttat atgaatattt accagaagat atagttgtaa aaactgttga
     6061 agaagttgat gaaagatttc attcaagata caatgtaaag tcaaagactt atatgtataa
     6121 aattgacaat aataagtatc ataatccttt tataagaaaa tatgctactc atgtaagtaa
     6181 aaaattagat ttagatagaa tgagaaaagc aagtgagtat ttagtaggag aacatgattt
     6241 tactagtttt gcttcttcta aatctaagaa aaaatcaaat gtaagagaaa tttattctat
     6301 aaatataaaa gaagatgata atgttataga aatatatgta gaaggaaatg gatttttgta
     6361 taacatggta aggataatag taggtgcatt gatagatgtt ggtctaaaaa gaagagctcc
     6421 acaagatatt aagtatatgc ttgaatcaaa agatagatgt caatcatcag atactgcacc
     6481 agctaaagga ctatgtcttt ggaaagtaac atattagtca attatataaa actctcttta
     6541 aaataaaaat aaaataaatt atatagttga cataaatgga aaaataaact attatatatt
     6601 ttataagaga gatataaaac tttatattta aatcctgtga gaaagagagt aacttctatg
     6661 tgttttatag agagctgagg atggtggaag cttagcaaat aagtattagt gaaaagaact
     6721 ttggaggata ctaattgaat ttagtatgtt agtaggtaat ctcgccttaa gagaaagagt
     6781 ggataagttt atcttatcaa ttagagtggt aacgcggata tatttcgtct cttggttttt
     6841 ccaagaggcg ttttttaata tatttaatta ttagtgttta tctggtatgt tgaacattta
     6901 ctaattgatt agctaagttt atcaataaga gtggtaccgc ggatatttcg cctcttagta
     6961 ttttaaaata ctaaggggtt tttttagtat taaaatgatt ttatgtgagt ctaaattctc
     7021 agagtcattc aatattaaga atttctataa aataaaaatt ataatttaag attgggagga
     7081 attaaaaatg aaggaaaaag tagtattagc atattcagga ggacttgaca catcaatcat
     7141 aataccttgg ttaaaggaaa attatgaaga tatagatgtt atagctgttt gtggaaatgt
     7201 aggtcaggaa gataaaatgg aagatgtata tgaaaaagct ttacaaagtg gagcatcaaa
     7261 ggcatatgtg gatgatataa gtgaagaatt tgtaactgaa actatattta aagccgtaaa
     7321 agcagaggct aaatatgaag gaaaatactt attaggaact tctttagcaa gacctataat
     7381 agctaaaaaa ttagttgaag ttgctcataa agaaggtgca aaatatatat gccatggatg
     7441 tacaggaaaa ggtaatgacc aagttagatt tgaagctaca attgcagctc ttgacccaac
     7501 tataaaagtt attgcacctt ggagaatttg ggatataaaa tcaagagaag atgctataga
     7561 ctatgctgaa aaacataata taaaggtaac agcaactaaa gctaaaatat attcagtaga
     7621 tgctaacctt tggcatgttt caacagaagg tggagatata gagcacctag aaaatgaaca
     7681 taaaaaagat gtttataaac aatgtgtaga cccagaagat gcatgtgatg tagctgaata
     7741 tgtagaagtt tactttgaaa aaggtgtacc taaaaaggta aatggcgaag aattatctcc
     7801 agttgcactg attcataagt taaatgagtt gggttgtaaa catggaattg gtgttataga
     7861 tatagttgag aatagacttg ttggtatgaa atcaagaggt atatatgaga ctccaggagg
     7921 aacaatcctt tatgaagcac ataatatttt agaaagtgct actttagaca aagatacatt
     7981 acatttcaaa caaatggtat cttataaata cggagaactt atttacaatg gactatggta
     8041 ttgtaaatta agagaatcta tagatgcatt tatggaacaa actcaagata atgttacagg
     8101 aacagtaaaa gttaaacttt acaaaggaaa tataaaacct gctggaatat ttactgaaaa
     8161 tgctctttat gatgagggaa tatcttcttt tggaaatagt gaactttatg accacaaaga
     8221 tgcagaagga tttattaatt tattcacttt accattaaaa atcagagcta tgaaagctgg
     8281 aaaataataa aataaattat ttaagagtgt ataaaaacta tttttaggtt tttatatgct
     8341 ctttttttat ttgaatttat taaattatac agtaaatagt ataaaaaaat atattatagt
     8401 tccaaatggc ttaataatgt gaaaatataa gacctaaaat ataaatttta taaatacaat
     8461 agttattgac tctctcattg taagagggtt tatactgaat ctaatgaaaa tttatagtga
     8521 ggagatagat tatatgagaa aaataattga aattaaacat cattcacatg attatgagtg
     8581 tatgtggaat ggtatagaag atttatatat aaataaaacc ggtgaatgcc ttccaaacga
     8641 ttttttcttt ttactgtcag gttttggttc attttgttat atgaaaacaa ataaagctga
     8701 tttgaaaaga atggtagctt tgggagatgg aaggacaaaa cagatgtata aatttttagc
     8761 accaattgtt ggatttgaat ataaacatca tgagtttaaa aagtatgagc aagcattaaa
     8821 gaaagcaaaa tctgaaattg atgatggata tccagttatt ttaggagctt tagatatgta
     8881 ttatctacca tattataaga aactatatca taaagaacat attccttttc attatatatt
     8941 aatggtagga tatgatgatg aaggaatata tctgtatgat tgtggtagaa cagaattatt
     9001 acatctttct tatgataaat tacgtgaaag catgaattgc aattcccctg gattaagcaa
     9061 agaaaatact atttgcacaa taagaatgaa tacttcaaag aataaatata acattgctag
     9121 agaagctatt gctataaagc gtgatatgtt tttaaatcca cctaaaggat ttttgggata
     9181 taaaggtttt gaaaagttta ttaaagagtt accacagtgg aacactgaat tggataaaga
     9241 tgattatgat aagattttga ccaatatggt tatgtttttt ggaacagtac caacaattcc
     9301 aaatgcaatc aaaggaatta aagaaccaga tactgttcaa tttaaaggtg gatttgataa
     9361 aatgagtaga atgctcaaca gtattgggga ggaatacaaa aacgactctt ttatacaagt
     9421 agctgatatt tttgataaaa ctgctattat aattgagaaa atatccaata ttataataga
     9481 ttacttaact caaacatgtg atgatacaga acaacttccg ttattgttct ctgaggtctt
     9541 agagcatatg aaaacaggat atttaatctt ggatgtataa aaaatatatt gttgacccta
     9601 acattacgta atagtgtaat atgaaaatat agcttgaata tattagtagg tattgatggc
     9661 tgtaaaatta aaatttgagg tgtggatatg agaacagtga aacaagtttc tgatttaact
     9721 ggaataagtg tgagggcatt acattattat gatgaaatag gtcttttaaa accaaataaa
     9781 attacagatg caggatatag actttatgat gatgaatcta ttaaaactct tcaacaaatt
     9841 ttatttttta aggagattga tattccttta agagaggtta aggaaataat gtcaagccaa
     9901 tattttgata aggttgaagc tctaaaaaat caaaaaaaat tacttatttt aaaacgaaag
     9961 agactggatg aattgataga gcttataaat caaactctaa gaggagaagg aaatattgat
    10021 tttaaagagt ttgatatgag cgagtatttt gatgttttag aagaatttaa aagagagcat
    10081 aggaataagg taattaaaat ttatggtagt gtagaaaaat acaatgaata tatagaaaga
    10141 gttaagtcta atgaagagaa aattgctaaa atggctataa aacaatatgg aactattgag
    10201 aagtttgcta aagctataaa aacaaatttt agcagtgata tattgaattt aggagaaaaa
    10261 tttgatagat ataaaaatga ttgtttaaaa gaaaaacatc caaaattaaa agaattatat
    10321 agaaagcttg tagaagattt aaataggaat ccttcttcaa cagaccttca agaaatagca
    10381 aaagagataa cagatatatc taaaaaagat tatgaaattt tctctatgga tactggtgat
    10441 gacaactggt attatatggt tcaaaattat ctagtaaatc ctatgtggat agaagaagta
    10501 gataaaaagt atggaagtgg agcaggtaag tttattggac aagtactaaa gacttatcta
    10561 agagatagaa aaccaaagat aaatacattg tatgaaaaac ttgtagaaga tttgagtaga
    10621 gattgttctt caagggaagt tcaaagcatt gttgaagaaa tagacaatga aatgaaaaga
    10681 agtaatgaat tttataaaat agacaatggt gaaagatact ttgattatat gtcagagctt
    10741 tatttacaag attctaacta tataaaagta actgataaga attatggtga tggtgcatct
    10801 aagtttattg gagaagcttt taagatttat tttgataata ataattgttg aaaatttgga
    10861 agtaaaaaat atgcaagttt tataaaagca caaaaataag gatgtagatt agctccatct
    10921 atatccttat ttaaagttat taaaatatat agtttacatc aaacttaaca ctttcaataa
    10981 tatttcccaa atatgttttt atactttcaa cttcttctaa agattttaat ttattttcag
    11041 tataaattgc tttgtccaga atattaaacc ttaatcctat ttcatcaaag tactcatgat
    11101 ttaaaacttt gtaccaatgg tttttttctt tattccaact cgtagatatt gaatcagctt
    11161 ctttttgagc tttttcccaa tcttcatttt ctatagattt ttctaaaaca gatatattgt
    11221 ctttatatcc ttctgtaaaa tcatatagtt tattgttaac ataaaatcca aataatacaa
    11281 ataagatagt ccatagtata acaaatgttg tagatttcaa tattaatcac cctttttatt
    11341 ttgaataaat attttgtcat tttcatctaa aacacaaata agaacatctt taaaagtttc
    11401 tatgtgatta gattttaaaa tacccattaa ccagttagta tctttttgag ctatgtctag
    11461 atttttattt attattctac catccagtat aagtgggata ggtaaatgat taaaagctct
    11521 tggaggagta ctattgtagc ttgatgctgg tacaacactt agattaccat cagtctccaa
    11581 aatagcatat tgtacatctt ttaggttaaa gtatccttga atcctaagtt gttctaataa
    11641 ttcatctata ctaattcttt cttttttaag ctctttatat acaatttttc ctttatctat
    11701 taatacagaa ggtttacctg ataaaaatga acttaatttt ctacttttta atgataagaa
    11761 tgaaattaga gtctgcatga ttacaagtcc agatattgct gcaacaccat ttatgattgg
    11821 tatattatta ttttccattg ggacagatgc aacttctgca attaatagtg ttataactaa
    11881 atcaaaacag ttcatttcag ctatttcacc ttttcccatg actctaagtg caattagcac
    11941 tgttatgtat aatataatac ttcttattaa tactactgtc atatctatca attactcctt
    12001 taaaaaatat ttacacttag ttagtatatc ctatataaaa aatttaattc aaagtataaa
    12061 aaaccttaaa taattggatt caactattta aggttttttt gataatttta atattaaatt
    12121 ttttatggat tttctgttac ttttatttat tttaataaca gattcaacaa aactcttttt
    12181 atctcctaat tttaagataa aatcaggata ttcttcaaat tcattgagtt ttattaattt
    12241 gaaagaagaa gatagatttt taaagttaat aattttagag ttattcacta atacacttct
    12301 ttttttaaaa taaatttctt ttttacttat atttagtata gttaatattt gtttaagata
    12361 tattattata tcttctggag ttctatcaaa tttgagttca aaattttcat cttcaaagta
    12421 gggaatataa tataaaggtg ttttgagagc aggtaattta ttatataatt cttcaagaat
    12481 atcgatattt ttaggggagt taaagaaaaa gcatttacat acattcatta aatccacagc
    12541 atctgaaagt gagttatgtt taatatctcc ttctacagaa aaaatttttt tcatattcag
    12601 taaagatatt tgcttagata agattctatt attgtatgta atatgttgag atataaaagg
    12661 ttgaatgtca atcatcatat taaataactc taagcattta cctgtatatt tatacactct
    12721 aaatgaagtt agaaggccag ttatatcaaa atcaccccaa ttatatattg taacatcatc
    12781 aaatttacaa aaccatttat aaaaatcatc cataacatat aaaagattag gagcattatt
    12841 gatatctagt tggttcaatt tggttaaatt tttacattta tttgaaagta ttttattgta
    12901 ttttggctta actaaagagt aataattatc tattgtatta aattcgttat caactaaaat
    12961 tccaccaata gaaattaatt ccgcaccatt atattctttt ggtttatttt tattatcgtc
    13021 tagtatatta aattcaaagt ctataaataa cttgtatttc ataaatctaa agcacatcct
    13081 caggtaaatt atttattgag cctaagcatc ataagaatca atagatataa tgactctaaa
    13141 catcaaaggt tcattacaac ttttatttat ttcataattt aattcaaata gatcttttaa
    13201 gatataattt ataagtattc tttcccaacc catttttaaa ttaactttag agtctattaa
    13261 tatattttct atctttttaa atatttctat atttgctggt attatactga gctcaatatt
    13321 acttttaaac gggttagact gtaaatctgt tataagtata ttttttaatt cctctgtaag
    13381 ttcagaaatt aaactatcac ctatgtattt ttttatgatt tcctctctaa tttcttttaa
    13441 atttagcaat attagtacct gctacttaca tagtagcttt tcctttccat ttaatactat
    13501 tattcatttt tgaatcttat ttagatatat tttaagatta aaagtcttta gctatataat
    13561 tttttaccca tttttaactt atattaacat attacagctt atatctccac cctgcttaca
    13621 ttgaggatgg agtatattgc ctattttgat aaaaatgata ggttgttatt tgcctattcc
    13681 tttttctgat aatttttcta acatatcttt ggtcatttta tctaaatcat aactaaactt
    13741 aaagttccat tcttttactg cactactact gtctagagag ttaggccaag aatcagctat
    13801 actttgtctt acagggtcta catcatattc tatcacaaaa tcaggaatat atttttttat
    13861 agaatcagct atttcttcag gagaaaagct catagcagta atattaaaag catttctatg
    13921 gatgagttta tcagctggag cttcgattaa atccactatt gattgaagtg catcaggcat
    13981 atacatcata tccatttttg taccttctgc tatataagat ttatatctct tattttttaa
    14041 tgcctcataa tatatatcaa ctgcataatc tgtagttcct ccaccaggag gcgtaacata
    14101 agaaataaga cctggaaatc taacacctct agtgtctact ccaaattttg agtgataata
    14161 atcacatagt aattctccag aaactttagt cacaccatac atagtattag gtctttgtaa
    14221 tgtatcttga ggagtcatat tttttggaga attttcacca aaagcagcaa ttgaactagg
    14281 tgtaaaaaat ttacaatcca attctttggc tatttcaaga ccatttatta atccattcat
    14341 atttaagttc caagcttcta gaggtttact ttcagcaact gcagaaagta aagatgctag
    14401 atgaattata gtatctacat catatttttt tgcaatttca aaaaaacgat tcttatctgt
    14461 aacatctaat atctcaaata taccagattc acatactgga ttaccttctt ttactctcct
    14521 tgaactagcg attacatttt gttctccata ctcatttcta agctttattg ttaattctga
    14581 acctatttgt cctaatgcac ctgttataag tatttttttc aatttcacaa cctcctaagg
    14641 gtttaattta tgtagtacta cttattttta ttttagcaaa tcttttgttt aaatacaaag
    14701 aattaaagat aataatatac gacttaattg aatgaagtgc agtaagtgcc taaaaattta
    14761 aagctaatat ataatagtat attgtataac aataaaagag tagattaaat tattatatat
    14821 agattgtgtg actaagtcac agaaaataga gttaatttaa tatataataa aagcatatca
    14881 agtaaagctt taaattaaag taactttata taaaaagtaa tataaattga taaaattata
    14941 aatttattta tagtgaatat gggttggatt ttatagatac aaaaatagta tatatgatat
    15001 gtagaccatt agcatgttta aagtagcaaa acatataaaa taaaatttga aaggaagtat
    15061 aaaaatgaca agaccatcaa tatatcatag ccaaggatac acttgtgcag aggcattaat
    15121 aaagtcttat aatgaggaac ataacacaga tataccaatc tcaataggaa gtggtatggg
    15181 ggttggaatg aatgttggaa gtgtttgtgg agctgtaaat gctgctgttg ttataatagg
    15241 gtatttaaat gggcgaaata gtaatttaga tgaaaatata gcaaggaagt attcaagaga
    15301 gctattgaat agagtaagaa ataaatacag ctcagaaata tgtgtatctc ttaaaaaaaa
    15361 taaagtaact tgtgaagaaa taataaattt cacatatgat gctctaaatg atatgctaaa
    15421 aaatcaaaaa taattctaag aaacaagtat tttacattcg atagaatact tgttttttta
    15481 tgatattttt aataggtatc agtttattat aatttttaaa tcaattttat tatattttaa
    15541 ttgaaataat ctactttgaa aattactaac tgacaaaaga atatgattat agtatagaaa
    15601 aaatgtaaa
//
LOCUS       DAEQAF010000087        15575 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.090, whole genome shotgun sequence.
ACCESSION   DAEQAF010000087 DAEQAF010000000
VERSION     DAEQAF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15575
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.090"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            209..1285
                     /locus_tag="KRN00_002880"
     CDS             209..1285
                     /locus_tag="KRN00_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1828736.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(1388..2230)
                     /locus_tag="KRN00_002881"
     CDS             complement(1388..2230)
                     /locus_tag="KRN00_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1828737.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            2414..2986
                     /locus_tag="KRN00_002882"
     CDS             2414..2986
                     /locus_tag="KRN00_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1828738.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(3149..3421)
                     /locus_tag="KRN00_002883"
     CDS             complement(3149..3421)
                     /locus_tag="KRN00_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828739.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGTHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(3548..4420)
                     /locus_tag="KRN00_002884"
     CDS             complement(3548..4420)
                     /locus_tag="KRN00_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBH1828740.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(4707..7814)
                     /locus_tag="KRN00_002885"
     CDS             complement(4707..7814)
                     /locus_tag="KRN00_002885"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBH1828741.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGAKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(7907..8139)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8314..8841)
                     /locus_tag="KRN00_002886"
     CDS             complement(8314..8841)
                     /locus_tag="KRN00_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBH1828742.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(8876..9661)
                     /locus_tag="KRN00_002887"
     CDS             complement(8876..9661)
                     /locus_tag="KRN00_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBH1828743.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLQKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(9671..9928)
                     /locus_tag="KRN00_002888"
     CDS             complement(9671..9928)
                     /locus_tag="KRN00_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBH1828744.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(9947..10405)
                     /locus_tag="KRN00_002889"
     CDS             complement(9947..10405)
                     /locus_tag="KRN00_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBH1828745.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(10445..11149)
                     /locus_tag="KRN00_002890"
     CDS             complement(10445..11149)
                     /locus_tag="KRN00_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBH1828746.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(11159..11794)
                     /locus_tag="KRN00_002891"
     CDS             complement(11159..11794)
                     /locus_tag="KRN00_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828747.1"
                     /translation="MKKVKYTRLVILGILIYLVFNTLVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFEKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKCGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            12175..13215
                     /locus_tag="KRN00_002892"
     CDS             12175..13215
                     /locus_tag="KRN00_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1828748.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(13678..15033)
                     /locus_tag="KRN00_002893"
     CDS             complement(13678..15033)
                     /locus_tag="KRN00_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBH1828749.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(15059..15328)
                     /locus_tag="KRN00_002894"
     CDS             complement(15059..15328)
                     /locus_tag="KRN00_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBH1828750.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
BASE COUNT         4957 a         2709 c         1799 g         6110 t
ORIGIN      
        1 aactttatag acttaattta ttacttttat agaattttca caataaaaag tcattttact
       61 tccgtattta atgcaaaagt agagattaaa cttaatataa aaaatatata acaaattttt
      121 tttatatttc tagaagaaaa gtatactctt ttttgtttaa taatgctaaa attgatttgt
      181 attgaatttt gattaggagg aaattattat gaaagctcaa agattaaatg ctgtacttga
      241 acaaatgaaa aaagatgata tttctcaaat gttagtaagt gaccctactt ctatatttta
      301 tcttacagga gtactaatcc atccaggcga aagactatta gcattatact taaatttaaa
      361 tggcaataat aaattattta taaatgaatt attcccagtt tcagaagatt taggtgttga
      421 aatggtttgg tttaatgata ctcaaaatcc agtagaaata ataactgaac atatagacaa
      481 aaatgctact atgggtgttg ataaaaactg gccagctaga ttcttattaa acttaataga
      541 attaggtgga ggaagtaagt ttgtaaattc atcttatata atagatactt taagaatgtg
      601 taaagatgaa gaagaaaaag agttaatgag aatagcttca aaattaaatg acaaggctat
      661 ggaacaactt aaagctactg tttctggtga acttacagaa aaacaacttg ttggtaaatt
      721 atctaaaata tatgaagacc taggtactga tggattttca tttgacccta ttataggttt
      781 tggacctaat ggagctaatc cacatggtga acctggaaat gcacttgtga aaccaggaga
      841 tgcaataatc ttagatatag gttgtataaa agataactat tgtgctgata tgacaagaac
      901 tgtattctat aaagaaatac ctgaaaaagg tagagaaata tttgaaatag ttcttgaagc
      961 taataagaga gctgaagcta ttgtaaaacc aggtgttaga ttctgtgata tagatgctgc
     1021 tgctcgtgac tacataactg aaaagggata tggacagtac ttcactcata gaactggtca
     1081 ctctatagga cttgaagttc atgataaagg agatgtatct tctataaata cagatactgt
     1141 acaaccagga atgatattct ctatagagcc aggtatatat ttaccaggtg agttcggagt
     1201 tagaatagaa gatttagtac ttgttactga agatggttgt gagatattaa acaaacatga
     1261 caaagaaata tgtgtagttg gttaattcta aaatcaattt gataaaatta aaaagccata
     1321 taaaaatgtt ttaaacattt ttatatggct ttaatttctc aatctatgat ttatttcaat
     1381 ccattattta tattgcagtt attaagattg caccctttga agtatatgtc cccatcactg
     1441 aaccaatttc acagattaca acatctttgt attttacatc cttttccata acttccctta
     1501 ccttttgagc cttttctggg caattagcat gtcctataaa taaaaccttt tcttctttat
     1561 ctttaatttt tgactctact aaagtaatca gctttttcaa actgtttcct tcacctcttg
     1621 ccttatctat aggagttaca acgccatctg caacttgtat tatcgcctta aaatttaagg
     1681 tatttataat ttttcctgct attggattta ttctaccacc cttaatagca ttttctaaag
     1741 tttcaagtgt tccaaaaaat ggaggattat ctttatattt atttattatt gaaacaatct
     1801 cttcaatttc ttttccttct tttattaata ttgctgcttt taacactaat tgtcctattc
     1861 caattgaccc actaagtgaa tctataacct caactttctt gttatttcct tccttttcaa
     1921 acatatcttt tgctaaaagt gcactattat aagtcccaga taatcctgaa cttatattaa
     1981 tcactaatac actttcttcc tgacaatggt atgcttctaa aaatttatca ggagaaggac
     2041 atgatgtttt tggtagtact ttactctcac tcatttttct atagaaagtt tcattatcta
     2101 tttcctttcc agatatataa ctttcttctc caaaagatac atttaaacca acaacttcta
     2161 tgttgtattt ttctattata tcatcaggta agtcacatgc actgtccact atcaatttta
     2221 ttttatccat attaacctca ctataagata ttattttatt tattcagtcg gtcgtacgac
     2281 cgatttaatt attattttat atattgaatg aaaaaaagtc aatagatata gattctcgct
     2341 ttattgacaa taaatatcca taagcttata atgttattaa tttgttataa atatacatgg
     2401 aaaggtaggt tttatgaaaa caaataatat gaaacaggct attttatcat ctgcaaccaa
     2461 tttaatagcc aaaaatggag ttcaaaatac tagccttgct gatattgcaa aagatgtaaa
     2521 tataagtaaa ggtactttgt attatcacta cgcatctaaa gatgatatta tatatgatat
     2581 tgcggatact catttagaag ttataactag tgctatacta aactgtgtaa aaaatgtcaa
     2641 atcaaaaaat tctcaaatag aaatggttaa cttaatctta gagaaaatat ctactataga
     2701 aagtcgtggt agggtacata tgtatcttat ttgtgaggca attacttcaa ataatgattt
     2761 aaaggaaaga ataagattaa aatatattga atggagaact actcttaaat ctgaaattgt
     2821 tgaatcacta gaaaaatata atagtagcga aaatgaacag gatgctgaat cattttcttt
     2881 tttactcatg tcaatagttg atggtttagt tgtccaaagt ttattaaaaa cagaaaaaat
     2941 accttatgaa aatatagctt cttttttagt taatcattgg atttaaactt aatacttaga
     3001 taattaataa aagtgaacta tttaagttat ctactttaac agttcacttt cttatttatt
     3061 ctcaataatt tttacttaaa acattcaatt tttatttaaa ccttcatgga atcacaaaat
     3121 aaaaatctct tataaattta aaatgttttt atttatgttc atgtgtatgc ccatctgaat
     3181 gttcatgacc atgtgtatgt gtatgctcat ggctatgctc atgagtacct gaaaaaccat
     3241 catcatgatt atggtcgtga cctacaccat ttacatgctc atgttcatgc ccatgactgt
     3301 gagaatgttg atgtgaatgt tcatggttat ctcctccaca gcatccttct cctccagtcc
     3361 cacaacaccc acttgtatgt ggattatgat gatttcttac tacaaatctc tctcttaaca
     3421 taattcttat acctcctagt atattattga gtacttcatg taccccatta actacagtat
     3481 acatctaact aggtataatc tcaatacata tggcattttt taacatatat aattaacata
     3541 tataatctta aagaaattta tccttaaaac ctccaccttt tacttcttca acgttattga
     3601 cagaaataaa agcttcacta tccatatcat aaattaaatc tttaaattta cctatttcat
     3661 ttgcagatat tatgcaataa atcatctttt tcttattttg tgtatatgca ccttctgcct
     3721 ccaaaaaagt gactcctcta cccattttat tcattatcac tttggatatt tcatcatatt
     3781 tatttgatat taaaagtata gatttttttc tatcaaagca atcttttcct atatccatag
     3841 taaaagaaat tatatacatt gtaattaaag tgtacatcac caatttagct ccaaataaaa
     3901 aagctcctgc acatactaca aaaaaattaa taaataaaaa tgtatttttc ataggtatat
     3961 catactttct tttcattatg gctgctatta tatcaagtcc tccagcagta gctcttgctt
     4021 taaaagttaa ccccatacct ataccagtta atgcaccacc ataaatacac tgtagcatag
     4081 tatcatctat tgggaaatat ttagcaatat cttgtgttag ccccagtgct agagaaaata
     4141 gtaacatatt gacaaaactt attagcaaaa atttattatc aaaatacttt ctagctataa
     4201 taaatattgg tatgttcatc aagaaacttg atattccctg atttatacca aataatttgt
     4261 ataatataac acaaattcca gctactcctc cacttaataa cttggctggt gctagatata
     4321 aatttattcc taaggttgat agaatcatac ccaatataat aagacaatat tgtaaaaata
     4381 tattattatc aatacttagc tttttacttt caccatacat caaaacgcac ccctttgcat
     4441 aataaataaa ccaccctgca taacacacga taaatttaca aataaattta tcagaagtag
     4501 tttcctaaaa atattattca tcctcactta aacgtttatt cattaatatt ctatcacatg
     4561 acataaataa tttatatgat ttatatagat ttatttattg taaattttgg aatattaaaa
     4621 cattttattg aatagataat tatattacat aaaaaatccc tatagaaatc tataaactaa
     4681 tttctatagg gattttggtt aactaactat ttttttataa cttttatacc tgtcatatgg
     4741 tcatttaagt tttgttcctc taaagattta tcatctactc tgtttatttc taaagctaaa
     4801 gtttcagact tgatatattc attaaaatgg tcaacagcct tagcaatttc atcatcacca
     4861 cagtattcta ttactatatt atctaatact tcaaagttat tagattttct taattgctgt
     4921 actttagata taaattctct agcataacct tcattaatca actcttcagt tagcttagta
     4981 tctagtataa caaaaagatt gttttcaaca gatacattaa acccttcctt agcagttata
     5041 cctattaata ctaaatcctt attaaattca aaagcttcac catctaaatc aactgttaaa
     5101 gtctcacctt tttcaagttt attagcagtt tcatgagcat ttaatttact taatgctcca
     5161 acgaataaat tcatcttagc acctaataat ggccctgctt ccttaaagtt tggttttaaa
     5221 ctaaagttca tatactcatc taaatcctta gcaaatatta cctctttaac attaagctct
     5281 tcttttatta aatcaactac atcacttatt gtatcttcaa acttaccatc tactaacact
     5341 ttttgtaatg gttgacgaac ttttattctt tctacttctc ttgaagctct acctaaagta
     5401 actaagtttt tagctaaatc cattttttct tctaatttag tatctactaa ctcttcatta
     5461 catttaggat attcagctaa atgaacagat acttctcctg ttaagtttct atacatttct
     5521 tctgacatat atggtgcaaa tggagctata gctctacaaa gaccatgtaa caattcataa
     5581 gttgtattgt acactgcttt tttatcttct gttaattcag ttgcccagaa tcttcttctt
     5641 gaacgtctta tataccagtt agataaatca tcatttataa aatcttgtat cattcttaaa
     5701 gttttattta actcaaatat agctaaattt tcttctacat ctttcattaa attattgaac
     5761 ttagataata tccatctatc aagttctggt ctatctttat attctacaaa aaattcagtt
     5821 ggatttatat catctgtgtt tgcatataaa gtaaagaagt tatatacatt cttcatagta
     5881 cctataaatt tactttggat ttcttttaat ccatccatat caaatttagt tggagtccat
     5941 ggtggagaaa catatagtaa ataccatctt aatgcatctg ctccatattg gtcaaataat
     6001 tccattggat ttactgtatt tcctcttgat ttactcattt tcttaccatc tttatcaagt
     6061 acaaggtctg gaactaaaac actcttatat ggtgcttttc ctaatacaaa tgttgatact
     6121 gcaagtaatg agtagaacca acctctagtc tggtctatac cttctgatat atagtcagct
     6181 gggaacaatt ggtcaaaatt ttccttattt tcaaatggat agtggtgttg agcaaatggc
     6241 atagccccac tatcaaacca acagtctata acctctgtta ctcttgtcat tggttttcca
     6301 catttttcac attttaagtg tatatcatct acatatggtc tatgaagttc aactgtttct
     6361 ggatttacat cttctatagc tttttcagct aattcagctc ttgaaccaac tgaatctgta
     6421 tgaccacatt cacatctcca tataggaagt ggagttcccc aatatctagt tcttgatatt
     6481 gcccagtcat ttagattttc taaccagttt ccaaatctct tctctcctac aaaacttggg
     6541 aaccatttta caccattatt attttctatt aatttatctt taagtttagt catctctata
     6601 taccagcttg gttttgcata gtatactaat ggagtttgac atctccagca gtgtggataa
     6661 ttatgaacta ctttttcttt gctatataat ttattttcag aagctagcca ttttattatt
     6721 tcaacatcta gcccatcttc cattacaaat ctaccttccc aaggagtaga tgtaaattta
     6781 ccagtttcat ctactggttg aataactggt aaatcatatc ttttacctgt gttgtagtca
     6841 tcttcaccaa atgctggtgc tgtatgaact ataccagttc catcttcagt agttacataa
     6901 tctcctactg taataaaaaa tgcttttttg tcaacttcta caaaaggcat taattgttca
     6961 tattctaaac cttctaggtc tttacctttc atttcttcta aaacttcata atcttcacct
     7021 agtactttat cagctaaagg tttagataca taatatacct catcaccttt tttaactttt
     7081 aaataatcta catcagcatt tactgttaat gaaacatttg atggtaaagt ccatggagtt
     7141 gttgtccatg ctaagaagta ttcatcagca tcttttttct taaatttagc tataactgta
     7201 ttagttttta cttctttata tccttgtgca acctcatgac tagcaagacc agttccacat
     7261 cttgggcaat aaggaagtat tttatgccct tcatatatat atccttcttt gttgaatttg
     7321 tttagtatcc accatacaga ctctatatag ttattatcta aagttatata tggattatct
     7381 aaatcaactt cataagccat tctctcagtc attattctcc attgtttttc aaatgagaaa
     7441 actgactctc tacatttttg gttaaattca gctattccat attcttctat ttgttgctta
     7501 ctagtaagtc ctaactcttt ctctacttgt atttcaactg gtaatccatg tgtatcccaa
     7561 ccagcttttc tctttacttg ataaccagac attgttttat atctacaaac tgaatcttta
     7621 agcgttctag ataaaacatg gtgtactcca ggatttccat tagctgttgg aggtccttca
     7681 tagaatacga aacttgggtc atctttccct ttttctaaag ttttttcaag tatatttatg
     7741 tctttccaat aatcaaaaac ttgtgcttct gcttgtttta cagaactgtc taccaatggc
     7801 ttaaatttcg ccatgtaaat caccctttcc tactaaatat tataattcca aaatttttta
     7861 ttctttcaca taaatttaaa tactaaaaaa ctcgccccct ttaaaccaaa gggacgagtt
     7921 ataaatcgcg ttaccaccct aattctatat gtaaactaaa tactagctac atataacact
     7981 ctaatagtat aacggtacta accggcacag cttagtagaa tttaatcgtt cagcctgcag
     8041 ctcaagagtg atttttatct ttataaattc attggttctc agcataccca attctctgta
     8101 aaattatcta aagataaatg tctctatcaa cgcttttaaa aatttatctg tgtttatatg
     8161 aaattctata acaaataatt tgaatagtca atatattttt gaaaaatata ataatttcta
     8221 tttttcttac atttttatcc tatttttaat ctttgttata gatttctcaa actcacacaa
     8281 ttattctaca taaaaaataa acaaattaca agcttattct aaagttgtag cagcttcatc
     8341 attactataa ttatacactg ttgttccttc aaatgcgttt acacattttt catctacatc
     8401 ataaaaaatc tcatcaacac ttcttatttc atcttctaac agtgatttaa atttatttct
     8461 aaatatctta aattctttga ctaaagcatc atactctttt cttatctcta taacacggtt
     8521 attagcttgt tctataattt gtctagcttt taaatcagct tcttcaacaa ttatcttagc
     8581 ctttttatta gccgcgctac aagtgtcttc tgctgcactt tgagcagtta ttaaagtagc
     8641 ttttagtgtt tcttcaatat tttcatactt gtttacttgg tcttgatata accctaattt
     8701 ttctttaaga gctgtatttt ccctacatag agattcataa tcttccttga tgatatctaa
     8761 aaattcatca acctcttcat ctctataccc tcttaaacct tttttaaact ctttattttc
     8821 tatctcaatt ggagttagca ttacatttcc tcccagctat aatttaaatt agtccttata
     8881 caattaatct tgcttgaact tttatttttc cttttttagt aatatctcct atttgtgtta
     8941 ccttagctct tcctttgcct ctaatagaaa tcaaatcatc attttttact attttagaag
     9001 ttgaagttat cttttcataa ttgacatgga ctttttctcc atttatgtat tttgcactat
     9061 cttgtctaga tatattgtaa ataccactta tcacacaatc taacctatct gaagatactg
     9121 taaatgatac ttctttatat tttgaagaac tattaacaat attttctctg gaaatttcct
     9181 ttacaattac attatttctt gaaacctttt gtaagtttac aattataaaa tcgcaaatat
     9241 cactacttac aactacttga caaaagctat catgtataat tatatctcca attttttctc
     9301 tttttatacc tagacccagt attgacccta agtaatcttt atgagatata tttttaaatt
     9361 tgaaattccc ttctatttgt aaaaatctaa gagtatcttc tatatcttca tattccatgt
     9421 aaaatggata aataaataca gtgcttcttt cagcttgttc ataacctcca tccacactgt
     9481 attttatttc atttgtagaa tttaatattg ctacagcatt tttcacttca tatggattaa
     9541 gaaactccgt agacttaaca tcatagtttt ttatacaact attagccttg tctatcactt
     9601 taaacatttt atttttcaag tctatatcct ttatgtgatt tgttagtttt aatttatcca
     9661 tcctatcacc ttagaatata accaatacta attgtcttag gaacatcaat aatactattg
     9721 caattaaagg agaaaaatct ataggtccat ttgtatattt atacattata gaccttattg
     9781 gcccttctat tggctctgta agattttcca aaatatcaaa aattttactt tgtcttccat
     9841 ttggaaacca agtcatcaag ctttttataa ctatcatcca tgctattata tctaaaagat
     9901 aataaagtgc aattcttatt gttcccatat attaaccgcc tttttactat ttattttgcc
     9961 aagggaagaa tgctttactt tctaattctt ttttcatatt tgcatctata tccacattat
    10021 taggagctag tataaatatt gatttagaaa ccttttgtat acttccatct aagacataaa
    10081 ctgccccatt cataaagtta aatatagatt tacgaacttc agaattagtc aatccttcca
    10141 aattcactat aactgccctt ctttgtttta gatggtctgc tatagttgca gcttcatcat
    10201 aaaccttagg ttcaactatt acaactttca tttggctagt tgtatgtaaa tttacaattt
    10261 tatttgcttt tgcagtacta aagccactgt tcatttcttc ttcttgaact atatcgtcca
    10321 tgccactttc atattcatct tcaatgtaat cttcttcttc atcaactatc caattcttaa
    10381 atttagatat tattccattt gacattatta acttcctcct taaaatttat tcaaatttga
    10441 gtaattattt tttattgtag tttctttctc caaagattga tgttccaact ctaacaatgg
    10501 tagccccttc ctctatagca atttcataat cgtgactcat tcccattgat aaaacatcca
    10561 tccctacatt agggatgttt agttctttta tttgttttga taaatcttta agacctttaa
    10621 atacacctct tatctcatct tcatcttcta taaaaggtgc cattgtcatt agacccttta
    10681 tttttatatt tttatatttt tctgacactt ctttgacaaa gtctacaact tcttctctat
    10741 caagtccatg cttagactct tctttagata tattcacttg tactaagcaa tctatttctc
    10801 tgtttatttg ttctgcacgt ttttgaattt cttcgcataa tgcaattcta tctaaagagt
    10861 gtatcataca aactttatcg attatgtact taactttatt ggtttgcaaa gttcctatca
    10921 ggtgccagtt taatttatca cctataatat catactttct agctaattct tggggtttat
    10981 tttcaccaac agaagtgatt ccttccctca ttgcctcatt aactaagtct acatcaacag
    11041 tctttgtgac tgccaaaagg gtaatctctt tgctgtctct atctactttt tttgcagctt
    11101 tatcaatttt gtttcttatc tcagacaaat tatctttaat agaacccatt attatcacct
    11161 actttatcct tatatttgtg tttatactgt taggtcttaa aattattttg tcatatagat
    11221 taacacttgt aactccattt atgtcatttt tataataatc cacaaataca gaagattcat
    11281 tctcataagt tattccttct aatatgacaa attttacact ttgtgattgt tcatcaatta
    11341 catatacacc acatttattg tcttttgttt ttatagaagt tttaggtatt tttaaacatt
    11401 ccatctgatt atatattata tcaaattctt cgacacttgt atcctgattt gcaacaattt
    11461 ggttacttat ttttaatttt accattattt tattattatt ttcatatatt ttgtaaactt
    11521 ttgcatctaa tttttgctca tgatattcaa ttattacatt ttgatttttt tcaaagttat
    11581 tagaatcttc tttactgatg tatgtagata gataattact ctggtcattg gcatcttttt
    11641 ctatagttcc ttttacatga atctttgcat caactttttc attttttaac accaacgtat
    11701 ctacattttt gctaattatc attactaatg tattaaatac taaatatata agaataccaa
    11761 gtatcactaa tctggtatat tttacctttt tcaaagactc tccccctata aaattacttt
    11821 cattataagt acttcttcta aaaaatgttt attccttttt tataagctaa tattttacgt
    11881 tctaataatt attttttcca tattaaattt attttttatc aatcttccta tacaagactg
    11941 cattatttat atataattgt attataaagt ataagtttaa tttacatttt atacgttaag
    12001 cttactttat atgtttttat agttattttt atttttagat acaatataaa accaattaag
    12061 atttaaaata acttttgtta tgttgacatt tatttaggta atcatttacg aatcaggata
    12121 acgttatcat agcaaaagtt tatgtcctaa aaaaaataca aggaggattt tcttatgtca
    12181 gaaattttat taggaacagg tttactttta ttggttctat gttgtttcac aatttttagt
    12241 tacaaggccc catatggtat gaaggctatg ggagctctag caaacgctgc atgtgctact
    12301 ttcttagtag aggcattcaa cctttcttta cttggtgatg ttttaggtat ggaatttttt
    12361 agaagtgttg gagctgctaa tggtagtctt ggtggagttg ctgctgctat acttgtgcct
    12421 ttagccttag gtgtatctcc agtttatgca gttttaatag gattatcttg tttagatttt
    12481 tctatattat ctggattcgt tgctggatac tttgtttctt tcttaattaa gtttatagag
    12541 aaaaaagtgc cacctggagt ggatttagtg gttgtaattc ttctatgtgc accgctatct
    12601 cgtcttatag catcaaatgt agacccatta gttaatagta cactactaca aattggacaa
    12661 gttttgatag aagctaccaa cattagccct ataataatgg gaattatact aggaggtcta
    12721 ataacagtag ttggaacgtc tccacttagt tcaatggctc ttacatctat aattggtctt
    12781 actggtcttc ctatggcaat aggagcatta ggtgcttttg gttcagcttt tatgaactca
    12841 acactatttg caaaattgaa attaggttct aaaaaagata ttatatctgt tgctattgaa
    12901 ccattaaccc aatcagacat aatttcagct aatccaatac ctatatattc tactaatttc
    12961 tttggaggag ccttttctgg tatcattgta gccttgatgg gtcttgtaaa catgacacca
    13021 ggtacagcta cacctgtggc tggttttgct ataatgtttg cttataatcc agttcaacaa
    13081 gttcttataa cagctggttt atgtgcttta ttcaatgtaa ttgcaggatt tttaggttca
    13141 aaaatattca gtacctttaa agttcttact gctggtgaaa tacgtggtac tgatgtagaa
    13201 gaagaaattg cttaaaaaac aataagattt ataaatttat atctcaagta gtagagtttt
    13261 atattgtagg caattttatt aattgcaaac gttttatttt ttatttatgt ttatgattat
    13321 tatgtgtgtt gaatatttag ataaattttt atttattatt tttatttaga tttttgttta
    13381 gttttttatt tggttgatat attaggaaca aaaattagta tagtttatta ctagttaaat
    13441 agcataactt tttagataca taaaaaattt tatattaatt agatattatt aaaataaaag
    13501 cgatacatga atttttaaat gtccatgtat cgctttattt ttgccataat cttaacaact
    13561 gatttttaaa gtttattatc ttaacaaagt tcattatctt atataatatt taaatgcata
    13621 gacttcttta atttaaccat ctaaatattt aattaaatat tattatatgt aatataacta
    13681 atttttaaat gaatgtatag gagctggaat ccttcctcct ctttgagtaa ataattcaga
    13741 tgaatttgta tttataggca ttactggtgc tcgtcctaaa agtcctccaa attctaccat
    13801 atcacctaca tcacatcctg gggctggtat aattctaacg gctgtagtct tattattaat
    13861 catacctatt gctgcctcat cagctatcat ggctccaagc gtacctgctg tagtatttcc
    13921 tggcacagct atcatatcaa gacctacaga acaaatagca gtcattgctt caagcttatc
    13981 tatacttaaa gcacctttaa taacagcatc aatcatacct gcatcttcag atactggtat
    14041 aaacgctcca ctaagtcctc caacatgtga acatgccatt actccacctt ttttaacagc
    14101 atcatttaaa agtgctaatg ctgctgtagt cccatgagta ccaacaactt caagacccat
    14161 ttcctctaat atatttgcta ccgaatcacc aatagcaggt gtaggagcta gtgataagtc
    14221 tattatccca aatggaacat ccaatctact agaagcttcc tttgccacaa gttgtccaac
    14281 tcttgtaatt ttaaatgcag tctttttaac tgtttctgaa acaacatcaa aaggctctcc
    14341 ctttactttc tctaaagctc tcttaacaac accagggcca cttacaccaa catttataat
    14401 tctatcagcc tcaccaacac catggaaagc tcctgccata aatggattat cttctactgc
    14461 attacaaaat actactaatt ttgcacaacc aaaacctttt gcatcttttg ttaattctgc
    14521 agtttctttt atgatttctc ccatttcttt cactgcatcc atatttatac cacatcttgt
    14581 agaacctaca tttactgaag cacatacttt attagtactt gctagagctt ttggaattga
    14641 cttaattagt atcttatcac cttttgtata tcccttttga actaatgctg agaatccacc
    14701 aataaaatct atacctaaat cctctgcagc cttatccaat gtctgtgcaa actttacata
    14761 gtcattttca tctgttgcac ctgcaataat ggaaattgga gttactgata cccttttatt
    14821 tacaattggg ataccaaatt cacgctctat atcttttcca accttcacca aatctttagc
    14881 agaactcata atcttattgt atattttttc tctagcttta tctccatcag ggtctataca
    14941 atctaataaa gaaatcccca tagttatagt tcttatatcc aactgttctt catctatcat
    15001 ctttattgtt tcaagtatat ttcctacatt cactattatc acctcccctt actgtctact
    15061 acagattatg cattgaatta aatatttctt ctcgctgaat ttttacatcc actgataatt
    15121 tcttacctct ttcaaccaag tcctcaaccg ttttctcaaa agaatttaat gatttctcta
    15181 aatcaactat cataatcata gtaaaataat cctgtaatat tttttgtgat atatctacta
    15241 tgttgatatt ttgcttgtat aattcatcac taattcctgc cactatacct ggtttatcct
    15301 ttccaattac tgttaaaatt gctttcataa taatatcctc ccttattttt ttataaatct
    15361 tatattttta caaattgaac tatgtgttaa catatatttc atttatttgt tagtaaacca
    15421 ctttttatgt atatatttaa tatattttaa tacctataca ttcatttgtc aatttttttt
    15481 caatattcta ttatttttat actatttaga aaattcatat attatatatg ttttctcaac
    15541 aacaaataca gttttcataa taatgaaagg tatta
//
LOCUS       DAEQAF010000088        15510 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.091, whole genome shotgun sequence.
ACCESSION   DAEQAF010000088 DAEQAF010000000
VERSION     DAEQAF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15510
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.091"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            21..872
                     /locus_tag="KRN00_002895"
     CDS             21..872
                     /locus_tag="KRN00_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBH1828751.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1005..2618)
                     /gene="ggt"
                     /locus_tag="KRN00_002896"
     CDS             complement(1005..2618)
                     /gene="ggt"
                     /locus_tag="KRN00_002896"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBH1828752.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2843..4780)
                     /locus_tag="KRN00_002897"
     CDS             complement(2843..4780)
                     /locus_tag="KRN00_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828753.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFLKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSVLAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDANEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKKELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4767..5534)
                     /locus_tag="KRN00_002898"
     CDS             complement(4767..5534)
                     /locus_tag="KRN00_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828754.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5822..6496
                     /locus_tag="KRN00_002899"
     CDS             5822..6496
                     /locus_tag="KRN00_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828755.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6520..7524
                     /locus_tag="KRN00_002900"
     CDS             6520..7524
                     /locus_tag="KRN00_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828756.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7636..8865
                     /locus_tag="KRN00_002901"
     CDS             7636..8865
                     /locus_tag="KRN00_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBH1828757.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIIAEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8873..9547
                     /locus_tag="KRN00_002902"
     CDS             8873..9547
                     /locus_tag="KRN00_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828758.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9550..10782
                     /locus_tag="KRN00_002903"
     CDS             9550..10782
                     /locus_tag="KRN00_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828759.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFAATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11068..12333)
                     /locus_tag="KRN00_002904"
     CDS             complement(11068..12333)
                     /locus_tag="KRN00_002904"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBH1828760.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12386..13534)
                     /locus_tag="KRN00_002905"
     CDS             complement(12386..13534)
                     /locus_tag="KRN00_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBH1828761.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13634..14179)
                     /locus_tag="KRN00_002906"
     CDS             complement(13634..14179)
                     /locus_tag="KRN00_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBH1828762.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14402..15346)
                     /locus_tag="KRN00_002907"
     CDS             complement(14402..15346)
                     /locus_tag="KRN00_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBH1828763.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
BASE COUNT         5420 a         2425 c         1945 g         5720 t
ORIGIN      
        1 aaacacagga ggtacattct ttgaaaaaca ttatttcagc aaaagaactt atatcaaaac
       61 tagaaaaaaa tgataatcta gttgtaatag attgtagatt tgatcttatc aatagaactt
      121 atggtattga ttcttataaa aaaggacaca tcaaaggcag ttttatctta gatatagaca
      181 aggatttatc atctcctaca aaagaacatg gtggtaaaaa tcctttacaa gaccctttaa
      241 tactaaaaga aaaattagaa aaaatgggtg ttgataacga cactacgatt gtaacttatg
      301 atgatggaga tttaaatgga gcttgcagat tatttttcca attaaaacat ttggggctta
      361 aaaatgtcta tgtactagat gggggaataa catctttcgt aaaggaaggt ggagaattag
      421 aagagaaagt gaatatacca agttgtacag gtaaggaaat tagaccaaat ataaacaatg
      481 atttagttgt tccaatggaa tatgttaagt ctaaattata caaaaaagat actgtaataa
      541 tagattgtcg tgctaatgag agataccagg gtttagttga acctgcttac tcaaaagctg
      601 gtcatatacc aagtgcaaaa aattattttt gtaaggattt aataaaaagt gactttgaaa
      661 atggctcact taaagatata gaatttttaa aaaaattctt taaagattta aataattatg
      721 atgaagtaat tttatcttgt ggttcaggga tatctgcttg tgttaacagt cttgctctta
      781 gagaactgga tatacctcac aagatttata ttggtagctt tagcgactgg attagttatg
      841 atgacaatga aatcaaaact ggtcaagaat aaggctcata atctatataa aatcagcata
      901 tgatagctta aattttgtaa aggcgtcagt cattgtagac tttcgccttt acttattatt
      961 tcatatactc tttaaattta ttatatatat tttagttgat aatattaata aactgcaata
     1021 tgaccatcac atcttgattc cgtcccacaa atataacttt cctgttctgt tttaaatatt
     1081 atttgacctc gtcccatgtc gacagtatca tgaattactt ttatttcatg acccttttca
     1141 attaatgaat ctattatatg ctttggcatc tctggttcaa cttctatttc ttttcctttt
     1201 atccactgcc atcttggagc atctagcgcc tcttgtggat ttaatccaaa atcaatcata
     1261 tttgttaaca cctgaatatg tccttgtggt tgcataaaag ctcccattac accaaatgga
     1321 cctattgctt tatcttcttt acctaaaaat ccaggtatta tagtatgata aggtttttta
     1381 aatggtttta ctacattgtg gtgtttaggg tctaaattaa aattatttcc tctactatgt
     1441 aaagcaatcc cagttcttgg tatcacaatt cctgaaccaa aatttatgta attgctctgt
     1501 atatatgaaa ccatatttcc atccttatct gcagtacaaa ggtatactgt accaccacaa
     1561 tatggctctc ctgcagttgg atacaaagcc tctttattgt caattaataa acttcttttt
     1621 ttggcatact cttggcttag taattcctga atctttacct tcatatgctc tatatcagtt
     1681 acatatgttt tagaatctgc aaaagctaat tttaaactct ctataatttt atgtatgtct
     1741 tctacatttt ctatatttcc ttctaattcc aattctttta atatgttaag tgccattaaa
     1801 actgttattc catgaccatt tggtgggatt tcaaatattt tatatccctt atattctgta
     1861 cttataggtt ctacccatgt tggataaaaa cactctaagt cactctttct tatagcccca
     1921 ttaaattttt tagaatattc atctatttta tcagcaagtc ttcctctata aaagctttca
     1981 gcctgagtat ttgctatctc ttctaatgta cttgcctgtt cttcacatat aaatatatct
     2041 ccagcctctg gggctttacc atctttagaa aatgtatcaa accatggttt gaactcttct
     2101 ccaataagtt ctttttcata gagttcatat gattttttcc ataccttagc tacattagga
     2161 gatactacgt atccctctct tgcatagttt atcgctggag ataagcattc cattaagcta
     2221 agtttaccat attttttatt taattctgac caagctgctg gtattccagg tacagttact
     2281 gctccaaacc catattttgg catttctttc atattattat aattttttaa ttccatattt
     2341 tctggagcaa agccactaga atttaaacca tacaatcgtt tttcttcctc tatccaaaca
     2401 agggcatatg catctcctcc aatcccattg cttgtaggtt ctactactgc taatgtggcg
     2461 gctgttgcaa ctgctgcatc aacagcattt ccaccctttt ttagtatttc aagtccagct
     2521 tgagatgcta gtggtgttga tgttgcaact gctccatttt tagcatacac gacatttctt
     2581 attgatgagt atttatgttg gtaggcatta aacttcataa atttcagctc ctcgtcattt
     2641 tttatttgat attctgctta gatttattat ataacatcaa gtaatgtaac tgatacaaaa
     2701 tgatataaaa tatagacttt ttcctaactt taattttatc tttaaataaa tatcttaaac
     2761 tcaattctag tattttctat ctgcacttaa ataagttatt ttattcaaaa catatatcta
     2821 attcttttaa cttaaaaata atttattctt ttatcatgtt tagagcatat tttaaagtta
     2881 aaaaataata tataaaatat cctataaaat aaatgactag agttatgata attggtacaa
     2941 gtaatgacct tggtataaac ttttgtgcta tagacatagc aaataaatta tgaactgtac
     3001 ctacaactaa tggcattaaa aatataactt ttaactgttt tgatattatt ttctcaatat
     3061 ctttattatt tgctccaagt tttattaaca taatatatct ttccttatca tcatatatat
     3121 ttgataattg tttaaataag attatactac ctgtacataa aagaaatact acagacaaaa
     3181 atatgcctat aaacagcatt agaccactta attttatcaa gttattataa ctttcaatac
     3241 ttgatgtaaa attaaaagga taagtaaatt tcatattttc acttactata ttttttaatt
     3301 ttaaagtcaa atccagttct tttttttcat tttttatatc aattaatctt attaatctag
     3361 aatttccatg taattttaac tgattaaata cgtcatcttt tactacaatt aaatcaaacg
     3421 tagcttgtga atttatttct ggctccaaga tgcttttttg tactttaaac agatttatat
     3481 catactcatt tgcatcttta atatgcaagt ttattttttc aatctcaaag tctttaaaaa
     3541 atattttttt gtatgaatca gaaacatagt acacagattc ctttgaagtt aattcttcat
     3601 aattgttatt ctgatattgt cttaattttt taaaatcact ttctctaata atatctacag
     3661 acgttctatc ttctatataa ctatttccat ttttataata catttcaata tttatatctt
     3721 tgtctataag ttctattgtt ttatcaaaga ttatcttatt atctttttta tatttatata
     3781 ataatttgtc aatttcgtta tttacataag aatttcctaa atttatggta taactgtatt
     3841 tataattttc acttatgttc ctatctatat cgtaataaag tgatatggta aaccctagca
     3901 tagttacact tgtagctatt aatattgcta ttacagccaa tacactacta ttgctcttta
     3961 atttaaatcc aagttcagaa aatgcaatta aattctgtcc cttataataa aaactttttc
     4021 tcttcttaac agcatcaata atcatataca tagttgatga aaaaaataaa aaagttccag
     4081 gtattattgt aactaatata aaaactgaaa gcataatatt ttcagcaata aaataactaa
     4141 ttgacattaa ataagaaata gctattaata aaacaccaag tacacatttt aactttataa
     4201 attttttaaa cttatacttt tctggatatt tattaaataa ctctataatt ctcttatttc
     4261 tgataactat agtatttctt attccaataa ctataaatat tattaaaaat acagctaatg
     4321 tctgaactaa ggcctttata cttaagttca tatttactac tatcatttca ttcattaatt
     4381 ttacaagcat catagtcata agctttaaaa ataacagtcc taaaaatata cctattagta
     4441 ttgcaactat acccatcaaa aaagtttcat ataaaaatat ttttcctatc tgatttttcc
     4501 tcattccaag taaactataa gttcctactt ctcgcctacg tctattgaaa aaaaatgagt
     4561 ttgaataata tataaataaa aatacaaata ccactattac aattgaactt gtattaatac
     4621 tcatcctggt tttctctcca agtgaactca acgcttcatt atactctata gatttaaaac
     4681 taaaaaatac aaatacacta aatacaattg aaataaagta cattaaataa ttaaaaaaac
     4741 tattctttac attttgcatt gcaattctaa ataaagtcat ttttattaac tcctccaatt
     4801 aaggaaactg tatttactat tttattatag aactctctgt tactttctcc ctttacaatt
     4861 tctgtgaata ttattccatc ctttataaag agtattctat tgcaaaaact cgcacttata
     4921 gcatcatgag ttaccatcaa tattgtttta ttgctgtctt tgtttaattt taatagacaa
     4981 ttcaacaaat ccctagcaga tttagaatct aatgctcctg taggctcatc tgcaagtact
     5041 aatgatggtt ttgttgctat agctctacat acagctcctc tttgcttttg tccaccagaa
     5101 acttcgccag ggtatttatc taatatagat tctatattta attcttttga aatctctttt
     5161 attctatttt ctattactga tactctttca ttttttaaag aaagaggcaa cattatattt
     5221 tcttttattg taagtgtatc caaaagatta gaatcttgaa atacaaagcc tagattatca
     5281 cgtctaaaat ctgccaattc attttgcttc attttaatag tattctttcc atttatataa
     5341 atatctcctg atgaaggtaa atctattgta gaaataatat ttaaaagtgt tgatttacca
     5401 gcaccggaag accccataat accaacaaat tctcctttat aaaccttgaa agttattcct
     5461 cttagagctt catgttttga accttttctt ccatactcct tttttatatt ttcaacagat
     5521 aatatttctt ccatagttaa taatcacctt tcatcacaat tagttattta tcaattctca
     5581 caaatatatt atatatatta aaatggcttt taaacattta attatattaa tttaaggtta
     5641 cattttcgta agtattaatt atatttcttc aaatttattg caattatgtt taaaatataa
     5701 tttatcaagt aaaatatagt tatattaata taattatttt aggtaataag gtagaaatat
     5761 tttaatttat caagtagaat atagttatgt taatataact attttgaatt aggaggtaag
     5821 aatgtttaaa ataatggtag ttgaagatga cgtctcattg aaaaatatca tagcaaagtg
     5881 tcttactaaa tggggacatg atgttcatca aatagaaaat cttgaaaata taatagaaga
     5941 gttcaaaaac tataacccag aattagtttt attggacata aaccttccat tttatgatgg
     6001 ttttcattgg tgtaatgaaa taagaaaaat ttcaaaagtt cctataattt ttatttcttc
     6061 aagaaattct aatatggatg taataatggg tgtaaattta ggtgcagatg attatataca
     6121 aaaacctttt tctgtagatg tcttagtagc taaagttaat gcccttttaa gaagaactta
     6181 taattttgtt gataataact caaatcagat tattcacaat ggtgttactt tagatttatc
     6241 aactgcaaca ataaactatg aagataatac tattgagcta acaaaaaatg aaatcaaaat
     6301 tctccatgag cttatgaaat ataaggggca gatagtaagt aggaataaac tcatgaaaaa
     6361 attatgggat aatgattggt ttgtagatga taatacatta actgtcaatg taaatagaat
     6421 acgctcaaaa ttaaatgaaa ttggtttaga agattttata gaaacaaaaa gaggattggg
     6481 ttatataatc agttaaaaca attctaagta ggtgaattta tgagctttaa agattttctc
     6541 aaggataaac taggtttttt agtatacaat tttactttct taatttttac agtatcagtt
     6601 attatatttt ctcctgtaga tgtttttctg actgatacta ttttatatat attagttgta
     6661 aatgttgtgt ttttattttt atatctattt attagctaca tcaagaagaa caaattttta
     6721 gataagataa aaaatgatac attcaaaatt aatatgaatg atatagaatt agctagatgt
     6781 aaaaatgaag aaaaaatata cttgaacatt attaaaaatc atcaatatca atgtaataac
     6841 ataataaata ataatatcga gaaatttgaa gaaaacaaag agattttaaa tatgtgggta
     6901 catgatgtaa agatacctat agctataata aaactcattc ttgaacaaaa tgaaaattta
     6961 attgatgaaa aaatttcaga tgacatagat agtgaaatat ttagaattga aaactccgtt
     7021 gaaaaaattt tatatttatc aagactcgaa gattttcata aggatttttt aattcaagag
     7081 gtaaatattg aaaaaatcat tagaaatatt ataaaaaaat actcaaaata ttttatttca
     7141 aaaaaaatta ttttagactt aaataatttg aattttaagg ttttatctga tgaaaaatgg
     7201 ctatacttca tattcgagca attattgagt aattccctaa aatactcctc attaggagat
     7261 aatatatcta tctattgcaa aagaaccaaa aattatttac aattaagagt ggaagatact
     7321 ggttgtggta taaaaaagga agatttaaat cgaatattca ataagggatt tacaggtaat
     7381 aatggaagaa acaattctaa atctacaggt cttgggcttt atttagtaaa agaactttgt
     7441 gataagcttg gtcataaaat tgatgtagat tcagagtaca accaatatac aaaatttact
     7501 attacattca aatgtgattt atagtatctt attattgata gtttattttc attaacttat
     7561 attcaacttc ttatagtaat tctatatgta catcccagta tataattaag tagtttttat
     7621 aaaaaggagg aagacatgtc ttttctaaaa aaatttaaaa ataaaagatt tagaaataac
     7681 agttttaaaa gtaacaactt tagaaatagc agttttggaa gtagtggctt caagtctaaa
     7741 aataaaggtt ttaaaaacaa tccctttaaa aataagagat tcaaaatata tgcaggaata
     7801 gcagtaatca tacttttaat tctaggagtt cttgcttatg ttgattcgaa aaacactgaa
     7861 ttacaagcta atgaaaattt tatcgaaaca tatactattc ctgaaaatga aaaaatattt
     7921 ataaatggga tggttgttcc taagcaaact aaggacttca atatatctgg agattatgag
     7981 ttaagtgatg ttaatgttac aaatggtcaa aaagtaaatc aaggagacct tctttttact
     8041 gctaaaaatc caactataat agcagaaata gatagtttaa aatcacaact tagtcaatac
     8101 aaaaaacaaa aaatatcact ttctgatatt gctgaaaata aagatgctat tgcttctata
     8161 aatgcacaga taactgcttt aaactctcag atagcttctc tggataaaaa agcttatgac
     8221 agagttactg ctccttttga tggcacagta tacttgaatg accaaactgg aaatccagac
     8281 caaccagttt catttatgac tattcaaggt ctagagtttt atatgaaagg acaagcaagt
     8341 gaacaagatt tacctaaaat gaagattgac caaatggtca atatactagt tttttcaact
     8401 gaccaaaagc ttactggtag aataagtttt atatctgata aaccatctac tccaaatact
     8461 gaaatgggag ctcagcagaa tacactatct tattatgata taaacatagc atttgataat
     8521 caagaaggat tagtaaatgg attccatctt caagcatcac ttgaagtagc taattcaagc
     8581 tttaaaatac cagcatcttg tgtacttaaa gacaacaaac actcatatgt atttaaggat
     8641 ttagatggta tattgaaaaa gcaaattgta gatgtagcaa gtcaaaatga tgattttgct
     8701 gtagttagag gcggtcttga acaaggcgat ataataataa aacaccctac taaagaaatg
     8761 aaagaaggag acccagttca aggcgatggc gtaactgctg gttctaataa tggagatact
     8821 actccaaaca aaaaagtaga agaagttact atggatgtga attaatttac atatgttaat
     8881 taaattagaa aatattcaaa aatattacaa agtagggaaa gatgaattac atgttttaaa
     8941 atccttaaat ttagaaattg aatctggaga atttgtcatg ataatgggta agtctggtag
     9001 tggtaaaact actttactta atatcttagg ttttctagat gtatttgatg aaggaagata
     9061 tatatttgat ggaacagatg taactaattt gagtgaaaat gaacgttctg tttttagaaa
     9121 tattaatatt ggatttgttt tccaacaatt taatttaata gaaactctaa atgtatatca
     9181 aaatgtagag ttgcctctaa tttacaataa agcactaaaa aaatctaata gagaagaaat
     9241 tgttaaagat aaattaagtt ctgttgggct tttggacaag cttaagcaga aaccacttca
     9301 attatctggt ggtcaacaac agcgtgtagc cattgcacgt tgcctagcaa atgaccctca
     9361 gataatcttt gctgatgaac cgactggggc attagatagt gaaactagca gagaaattat
     9421 ggagctttta acaaggctca acaaacaagg taagactata ataatggtta cacatgatca
     9481 agatttaact aagtatgcaa ctaaggttat acgacttaaa gatggtgtgt ttacttcgga
     9541 ggtgtaatca tgagtttatt aaaaaattct ttggccaatt taaaaggtca caagcttcgt
     9601 gtatttgtag ctttactctg gattataata ggaataactt cagtaatact tgttagttct
     9661 ataggtaatg gatttcaaaa agaaattaag aaatctgtaa acaatgtaaa ccctaataaa
     9721 actactattt cgtttgaatc agccgataac acaggtctta ctgatgatat gagtattttt
     9781 ttaaaaccct ttaatgcaaa agatttagaa gaattatcat ttgttgaagg agtagaaaga
     9841 atagctcctt caagagatgg gtttaacctt gattcagttt actcttcaca agcatctttt
     9901 gataaaaaaa ctacgtatgt tgatgttgga ccagtaaaaa aagattctaa aataaattta
     9961 atttgtggta gagatttttc tttagatgat gaaaaaagaa aagtaatttt acttacatta
    10021 caaagtacaa gtgaaatttt tgaaaatcca gaagatgcct taggtcatgg tatcaacata
    10081 aatggaacta tatttgaaat aataggggta ttagatgatt ctcagcaaaa ccaagctgga
    10141 ggattctttg gaggttacca agatatgcaa tttactactt ccctagtacc taaaaaggct
    10201 tttgacactt taatgagtca aaattcttat tcaaatgaaa tttaccagtt agacttagtt
    10261 tcttctaaag gctataatgt aaatgaagtt gcaaacaatg ttatagctaa attatatgag
    10321 atgcaccctg gtatcaatgg ttcttatact acaccagacc caactgaaca gacagcttat
    10381 cttgaaagca ttaattccaa tgtaaacaaa tatgtatcta taataactgt agttgcaatg
    10441 tttgttggtg gtattggtgt aatgaatata atgtatgtat ctgttatgga aagacaaaga
    10501 gaaattggta taagacgtgc tattggagca aaacctaggt ctatattatt tcaattttta
    10561 gttgaagctg tttttataac agtatgtggt ggaattttag gaactatagt tggatttgct
    10621 gctactaact atgtttctaa atatataggt tttgaagcta tacctagctt aaatagctta
    10681 ttttatgcaa ttgtagctac tatattgact ggagttgtat ttggtctgat tccagccttt
    10741 aaagcctcta aactagaccc tataaaggca atttataagt agaaattgta taaagatttt
    10801 cgatttttag attagtttat ataaaacata cttaaatata taacgcacta ttatatatga
    10861 tagattagga acttaatctt tccaaatata atagtgcgtt ctttcataaa aaggattctc
    10921 ttccttacta tatctaaatt accaagatgt tatgttctaa ttgttcaaac taatacttcc
    10981 aattttgatt aatcaatctc attctcctaa tatacaatct tttactttca atcattgtac
    11041 actccgcctt aaaaaaataa tcttaaatta tgcgttatat acaatctccc cattacatat
    11101 tgtataatta acctttccat ataaagattt acctttaaat ggtgaattat cagctttaga
    11161 aacaaagctt tcaactgtcc attcttcttc tggattgaat ataacaatgt ctgctacagc
    11221 cccttcttct ataaatccaa tatttaaatt gtacaacttt gcaggattta tagacatttt
    11281 ttctattaac tgcatcatac taagatgatt tttatgcacc aaatttgtta ttccaagagc
    11341 taaagaagtt tcaagcccaa taattccact tggagctttt ataaactctc tatctttttc
    11401 ttctttacta tgaggtgcat ggtccgttgc tattatttca atagtaccat catttaatcc
    11461 ctctataatc ttatctctgt cccatttact tcttagaggt ggattcattt ttgcatttgt
    11521 tccaaactcc aatacatctt cctcagtcaa tgtaaagtga tgtggtgaag cttctgcaac
    11581 tacatttgca cctaagtatt ttgcaaatct aaccatatca acagatacac ctgaacttat
    11641 atgttgtata tcaactttag caccagtctt tagtgccaac atacaatctc tggctaccat
    11701 aacatcttct gctacacttg atgcaccttt taatcctagt tctgaagcta cctttcctgc
    11761 atttacacct ggatttccaa ctaaagaagg gtcttcttca tgaaaactaa gtggtacatc
    11821 caactctttt gccttaatca ttgcctccat aattagattg ctatccatta aaggtaatcc
    11881 atcatcagta aaccctggta caccagcttt tttaagagct tccatatcaa ctaactcttt
    11941 accttcaaaa cctttagtta tagctgctgc ttgtaaaaca tttatacatg cattttttga
    12001 cttttcttta acataattaa aagtatcttc attatctaca ataggattag tatttgccat
    12061 acatataaca gttgtaaatc cacctctagc agcagattta gctccacttt ctatatcttc
    12121 tttatatgta aacccagggt ctctaaagtg tacatgtaca tccactaaac ctggagcaac
    12181 tacattacca ctagcatcta ttattttttc atattcatca ctttcatcaa acttgcctat
    12241 tttataaatt ttattttctt ttataattaa gtcaatattc tcatctcttt gacttttagg
    12301 gtctattact ctaccatttt taattaaaat catattattt ctcctttata tttttaattt
    12361 atatagactc atataatatt atacattatt ttacatactt aaatacaaaa ttacgtttga
    12421 catcaatagc ctttttagga caaagttcat ggcaacagta acatcttata catttactta
    12481 agtctataat agcaccctta gtccctatct ctatagtgga tgcaggacaa gcttccttgc
    12541 attttccaca ttttatgcaa tcttgaaatc ttaccacagg ctttggtgtt ataagctttg
    12601 aaataggttc atttaaaaat tttggtagct ttacagaaaa caatcttaaa tccttactta
    12661 catttggaat cttgtaattt tttataatta aatcttttat atcttcacct aaaatttcaa
    12721 tatctgaaaa atcttcttgt atatatcctc tcttaatagc acctctaatt gtagcaactc
    12781 tatttggaag taaacttata atcttacatg caacaacatc tatagcatat ggattttgtg
    12841 atgctaataa aactcctatt tctcgagtag taccagctga aggtccatca ccttccatac
    12901 ctactatacc atccataatt gtcaatgttg gttttatata atcacaaata tctaaaagta
    12961 cattttcgca aaacaactct tctgtaggaa atctataatg tatctctgct tttttcaatc
    13021 cagctatgca tccatataag ttttttgtac caccagtaaa agttgccatt atatgagtct
    13081 ttaatttaca aagatttatt atataatctg aatctactat tggtttaata atatccatat
    13141 attttagaac atgtgctttt tcactatgta tcttaacatc tgaaacatca taatttaact
    13201 taatgcccag ttcatttgct acttcttcaa ttccagatgc cttataaatg ctcttaagag
    13261 aactttgatt atatggacca ccagggctat ctgctattgt aatatcacaa tttaactcta
    13321 aaagtttttc acatacaact tttacaacca taggatgtgt agttgtagct tcttcaggct
    13381 tttttttcat taataaattt ggttttataa gtactttgct tcctttttta acaaacttat
    13441 ctataccacc aatatcctct aaattttttt caatagataa ctttacttct tcataattgt
    13501 aagttttaca actcctaaca gataccgact tcatattatc tccatccttc tatcacaaca
    13561 gtttatttgt ataatttaaa aaaggagaaa ccaaagtttc tccttttaat ctatgtttta
    13621 attgttttaa ttattatttt ccaaaatgtc tgtttaataa tcctaagaat gctttaccat
    13681 gtctagcttc gtctttacac atttcatgta ctgtatcatg tatagcatct aatcctaatt
    13741 ctttagctct cttagctaat tttaattttc catcagttgc accatactca gcatcaactc
    13801 taactcttaa gttttctttt gtatctgcaa ctacaacttc tccaagaagt tctgcaaatt
    13861 tagcagcatg ttcagcctct tcaaaagcta ttctcttata cgcttcagct acttctggat
    13921 aaccttctct atcagcttgt ctactcattg ctaaatacat tcctacttct gtacactcac
    13981 cagtaaagtt agctcttaat ccttcgatta tttctgcatc tacaccttga gctactccta
    14041 ttctatgttc atcagcccaa accatttcgc ctttcatttc ttcaaattta tcagctccaa
    14101 ctttacatac tggacattgt gctggtgcag catctccttc atgtatatat ccacatactg
    14161 tacaaacaaa ttttttcata attaatttcc tcccaatttt atataattaa atttttattt
    14221 ttaagtttaa taacttgcta caagaatata tataccccag actttatagc ttaaacacta
    14281 aaaataaaat ttatttccta attaatttta tcactttgaa acaccagtat caaccaagtt
    14341 ttgatgtcaa atttctacat aatacataat ttatttgatt aattaggaaa tagttgtcat
    14401 attaaatact ttctaatgaa gactcctctg aatctttaag tttcactttt ttgctcttta
    14461 aaaaagataa tttagtttct gcagttatga ttgcaacaaa tatcaagata ctaccaataa
    14521 ccaattttgc tgtaataagc tcctttaaaa ttattataga aaatattgta ccaaatacag
    14581 cctctgtgga taatattata gctgttctag ttccatcaac tcttttttga catatagtct
    14641 gaaataaaaa tccaattgta gtactaaata cagctagata catagttccc atgtaaccag
    14701 ataattcagc ttccatcttt aattgacctg caaatgtttg aactacaaca gacattaaaa
    14761 acgctactgt aaattgaata gctgtcaatg ccattgggtt gttatctttt gcaaactcac
    14821 ttgtaaagaa tatatgaaat gcaaatccga atgaacatat aagtgttaga aaatctccaa
    14881 aattaataga gaaatcagct tctaaagaaa gtatcccaat tcctataaga gctaccaaac
    14941 tacttattat tcctatttta tcaagttttc ttctataaag tataaatcct atgaatggaa
    15001 ctattacaac attagctgct gttataaacg catttttaga tggtgtagtg tacataagtc
    15061 caatagtttg tactgtgaat gctagaaata aaaatattcc taaaatccct cctgctttta
    15121 ataatttttt acccatattg gcacgaatct gtttaaaaaa cagtaaattc ataattatag
    15181 ctgccaagaa aaatcttaaa gttatgattt gtagaggtgt aagcccaccg tctaatgcaa
    15241 attgggttgc tacaaagcca cttccccata taattgctat aaatattagt cctatttctc
    15301 caaagtattt tttcaataaa gccccctcct ttttattttt ttgcaaaatt ataaaccccc
    15361 taaacagcaa gagagttttt ctataagcat tactataaat taatatagta aattttttca
    15421 gtattttaaa tctaaattta catacatttt gagctcaaat ttatatccac tatttaacag
    15481 taatatatta atcatttttt gtaaacacct
//
LOCUS       DAEQAF010000089        15500 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.092, whole genome shotgun sequence.
ACCESSION   DAEQAF010000089 DAEQAF010000000
VERSION     DAEQAF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15500
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.092"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            165..1556
                     /locus_tag="KRN00_002908"
     CDS             165..1556
                     /locus_tag="KRN00_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1828764.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            1809..3602
                     /locus_tag="KRN00_002909"
     CDS             1809..3602
                     /locus_tag="KRN00_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBH1828765.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIVPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(3683..5065)
                     /locus_tag="KRN00_002910"
     CDS             complement(3683..5065)
                     /locus_tag="KRN00_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1828766.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPSNGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            5323..5670
                     /locus_tag="KRN00_002911"
     CDS             5323..5670
                     /locus_tag="KRN00_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1828767.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            5688..6722
                     /locus_tag="KRN00_002912"
     CDS             5688..6722
                     /locus_tag="KRN00_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828768.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(6771..7820)
                     /locus_tag="KRN00_002913"
     CDS             complement(6771..7820)
                     /locus_tag="KRN00_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1828769.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGIFLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            8095..9630
                     /locus_tag="KRN00_002914"
     CDS             8095..9630
                     /locus_tag="KRN00_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828770.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(9816..10502)
                     /locus_tag="KRN00_002915"
     CDS             complement(9816..10502)
                     /locus_tag="KRN00_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBH1828771.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALNSI"
     gene            10627..12009
                     /locus_tag="KRN00_002916"
     CDS             10627..12009
                     /locus_tag="KRN00_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1828772.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            12411..13679
                     /gene="eam"
                     /locus_tag="KRN00_002917"
     CDS             12411..13679
                     /gene="eam"
                     /locus_tag="KRN00_002917"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBH1828773.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDICDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(13772..14128)
                     /locus_tag="KRN00_002918"
     CDS             complement(13772..14128)
                     /locus_tag="KRN00_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828774.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTSEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(14279..15373)
                     /locus_tag="KRN00_002919"
     CDS             complement(14279..15373)
                     /locus_tag="KRN00_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1828775.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
BASE COUNT         6007 a         1916 c         2491 g         5086 t
ORIGIN      
        1 aaataatatt tttcataatt ttaaaaataa taataaaaaa atgaaaatac aggcgataat
       61 ctattgagta aacatagaaa agatgatatt ataagtatgt gctaaaatgg ttaaagcaat
      121 attaatatta aatttaacta taaaacaaaa gggggcgttt ttttatgtca agtacagaaa
      181 gcgtatctaa aaaaagtggt catccgaaga gtttttggct tatttgcatg acaattttgt
      241 gggaaagatt tagttattat ggtttaacag ctttattggt attatttttt acagcaagtg
      301 tagctcaagg tggtttaggt ctttctactc aagaagcaac atccatgttt ggcttattta
      361 caggtcttat atatcttaca ccattagtcg gtggctggtt agcagataaa gttttaggtc
      421 aacaaaaatg tatttctata ggtgcacttt taatagcaat aggagatttc gtactatttg
      481 cttcatctac atctattgca atggtttggg taggtctatc aataattatt ttaggaaatg
      541 gtttttttaa atcaagttgc tcaaatatag ttggggatat atatcctaaa actgatgtgt
      601 caagaaaaga tgcagcatac agtttattct atatggcagt aaatgtagga gcatttatag
      661 ctccaataat atgtggattg ctttctgata atgtatttgc agtaagagga gcaagtggag
      721 atatagtatc ttatggatat aagatggcat ttttaatttg tggtataggc atgatgttag
      781 gtatgattat atttacactt cttgcaccaa aattattaaa tgaagttgga aaatatcctg
      841 tgactaaagg taataaaggt gaaaaaattg agtatggacc acttactaag ttggagaaaa
      901 ataggataat agcaatggtt attttatttt tatttgtggt cttattctgg acagcatact
      961 atcaaacaca aagttctttt atgatttatg taagggataa tgtaaataga actctatttg
     1021 gatttgaaat gccagtagca tggcttacat cactaaatgc tatattatgt gtggctttat
     1081 gcccagtatt agctacccta tgggttaaat tatctcatac caaaagaggt gatttctcta
     1141 ttccagttaa aatgggatta ggaatgataa taatgggtgt tgggtttata gttatggtat
     1201 ttgctacatt agctaatggt ccagatggaa tggtaaaggc tagtatattg tttatagtat
     1261 tgacttatat atttacaaca gtaggtgaat tattcttatc tcctatagga cttgcaatgt
     1321 tcaataaatt agctccagct aagtatgcta cgttgtctat gggagcctgg tatctaacaa
     1381 gtttttttgc aagtttatta tcaggaaaga ttgctggttt tacagccaca cttggttttt
     1441 tacagatatt tggaggaata gcaacagttt taataatatt tggtttaata ttattgggaa
     1501 taagaaatgt attaacaaga ttaatggcta tggatttact aacaaaagaa aaataattca
     1561 tgacgaatta ttgtaaataa atgaattact ttaaataaag gaagttacat ttaaatataa
     1621 aattaaatgt aatttcctct ttgattatga aaaaaagctt tacacaaata gatattataa
     1681 ttaaaattat aattgtgata attagagtgt ataagattta tataaattat acaaaaaata
     1741 tttatgtaat aaactttaca tacttatata tttagttatt caaactatta tttcgaggag
     1801 gtcttgttgt gaatataaaa gatagattaa gtggattaag aaaatttatg gaagaaaaaa
     1861 atatagatgc ctatatgatt ccatcttctg acaatcacca aagtgaatat gtaggagatt
     1921 acttcaaatc aagagaattt atatcagggt ttaatggttc agcagggacg gttattgtga
     1981 ctaaagacga agctgggtta tggacagatg gaagatattt tatacaggca gaatctcaat
     2041 tagaaggaag tacaataaaa ttattcaaaa tgggacaaga aggttgccca actacagatg
     2101 aatatttata taaaaatatt cctgaaggag gaactttagg atttgatggt agagttatat
     2161 ctgctagaga aggagctaca ttagctgaaa aattatctaa aaaaggtata aagatagaat
     2221 atcagtatga tttaatagat agtatatggc cagatagacc tgctttatca gatagtaaag
     2281 catttttatt agatgttaaa tattgtggag aaagttttag ctcaaaatta gctagattaa
     2341 gagaaaaaat gagtgaaaaa ggtacttcta ctcatgtaat aactactctt gatgatatag
     2401 catggttatt caatataaga ggtggagatg ttaaatataa tccagttgta ctttcttatg
     2461 cagtaataac tttaaaagaa gtttatctat ttgttgatga aagtaagtta aatgaagaaa
     2521 tactaaatga actagctaag gaaaatgttc aaataaagcc atataatgat gtgtatgaat
     2581 ttgtaaaaaa tatagacaaa actgaaaaag ttttattaga tggaactaag cttagttata
     2641 caatttacaa taatatacct tgtgaagttg agaaagttga tgagttcaat ccagtaatgt
     2701 tttttaaagc tcaaaaaaat gaggtagaat tagaaaatat aagaaattca catgtaaaag
     2761 atggtgtagc tttcactaaa tttatgtact ggttaaagaa aaatgtaggt aagatggaaa
     2821 tcactgaaat aagtgctact caaaaattag aggacttaag aagagagcaa gaaggtttct
     2881 ttgagccaag tttcaataca attgctgcat ataaagagca tgctgcaatg atgcactata
     2941 gtgcaactcc agagtcaaat tataaattag aggcagaagg attattttta gtagattcag
     3001 gtggacaata ttatgatgga actactgata taactaggac tacagtttta ggacctataa
     3061 gtgatgaatt aaaactacac tttacttctg tagcaagagg aatgataaat ctttctaagg
     3121 ctaagttctt gcatggttgt agaggatata acttagacat actatctaga agttgcatgt
     3181 ggaatatggg aattgattat caatgtggaa ctggacatgg tataggattt gtgctaaatg
     3241 ttcacgaagc tccaaatgga tttagatgga gagtagtacc tgaaagattt gatagtgcag
     3301 ttcttgaaga aggaatggta actactaatg aaccaggtat atatatagaa ggttctcatg
     3361 gtataagaac agagaatgaa attgtagtta gaaaagctga aaagaatttc tatggtcaat
     3421 ttatggaatt tgaagttgtt acgttagctc ctattgactt agatggtata gtaccagaat
     3481 taatgaataa ggatgaaaaa gattatttaa actggtatca taagttagtt tatgataaaa
     3541 tatcaccttt cttaactgat gaagaaagag aatggttaaa agtttacact agagctatat
     3601 agtttgtact agatacaata aaaatcgagg tattataatg cctcgatttt ttattgtata
     3661 ttttattaac tttaaaaaat ttttaatttg ataattctac taatttttta ttcattataa
     3721 gtagtataat tccaaatatc aataaaaatg atggtatcac tatgaagact tgtaacatac
     3781 caagttggtc tataatagct tgcgtatagc cagataattt atttgctgca aatttgccta
     3841 aaaaccaaac acccattagg aatgaaatat acttttcagg cgaaagttta tttaccatac
     3901 catacccgac tggagaaaag caaatttctc ctatactttg gaatgttaaa aatccaacta
     3961 cccaaaatac acttgctttg tgaattgaat tagggtctgt tcctgtttgt ataactgcta
     4021 ctatcataaa caaaaatgct atggctaata gtataaaacc taagctcatt ttttttggca
     4081 cacttaaatc gcctttttta gtttgagata attttaccca tactaaagca gagataggtc
     4141 caagaataac acaaaggaga ccattatatg aatctatcca tgaagtagga atttgaaaat
     4201 tgccaacagt aagatttatg tgttcctttg tatagagtgc aatagacata gaggcttggt
     4261 tatatgctat ccaaaaaaat actgtgaaaa aagctaacac caatattact attattcttt
     4321 ttttctcaat caaagttaaa ggtcttgaag ctagcatttt cttatattct agtgattttc
     4381 ttatagactc tctcccgtta ctagggtcat tattcaaagg tttataaaac tttctgtttc
     4441 caaatataaa gaagaataaa cctattagaa ccgtaattga tgaaaataaa aatacatatc
     4501 tatatccata catacttata gataatccgc ttttcatagc aaaccattca ttagcaacta
     4561 aaccgcatat taaagggcca aataaggtac ctagattagt agccatatac gtaatagaga
     4621 aagctccatc ttttcttggg tcatcattgg tatataagtt tccaaccata gtatgtaagt
     4681 ttcctttata aaaacctatt cctaatccag ataaaaatat catgatgttt atatccatct
     4741 tactatttgc tatgtatcct agaaaataac caattgaaac cattagcatt ccaagtataa
     4801 tacagttttt gggacctaaa aatctatcac tgacccatcc accaataact ggagagaaat
     4861 aagtccatgc taaaaaagat gcaagcattg atgcggattc tgctggtgtt aaccctaaac
     4921 cacctttgga gacttgttca gctaaaaaca ataataatac caatttcata ccatagtatg
     4981 caagtcctac aaaggtaaat attgaacagc agaaatataa atctctaggt tgtttaagtt
     5041 tttcttgcgt ttttaaaact gacatatgtc gagaacctcc agataaatag tttaacaaaa
     5101 ttttaccata ctatatgagt atatgttttt ttcatataga cgtcaacttg taagataatt
     5161 taattaagtc gaaatatatg taaaaatagt atcatttttg tgtattcagt aatatttttt
     5221 tatgataata tatgttatta ttatattaaa atacaaacat atttatggaa aggatatgcc
     5281 aatttagtag ttagattgat tgtttggcag gtgggatgag ctatgataag aaagaaatct
     5341 gaattacaag tagaagtaaa agaaaattta aatggtggta taggaaaggt taagcttgaa
     5401 aacataatac aaaatgaaga gcttaaagga aaaggaagac tatttaaaag agtagcttta
     5461 ccagtaggaa gttcaattgg tgtgcatgac catacaacag attttgaagt atattatata
     5521 ctaaagggaa aaggtaaagt atttgataat ggggaatttg tagaagtaaa tgagggtgat
     5581 gtagtgtata cagctgatgg cgaaaaacat tctatagaaa atataggaga agaagatctt
     5641 gagtttgtag cactagtttt atatatgtaa aatatggagg aggagtcatg acaggcaaga
     5701 tagaagaaat taaggacaag ataaatagat tttgcaactc caatttaaat caagaataca
     5761 aagatataag ctttaaaatt ttgcaaaacc ttttagataa taataaagag ataattcatt
     5821 cttctagagc tgatatatgg tcttcagcta tactaaatat agttttagaa caaaatcttt
     5881 tatacaataa gaagcatcca ctacatataa caaaaaaaga gttttcaaaa caaataggtg
     5941 tttctttaaa tactataaat aataaatcgt ctttaataaa ggatgtttgt agtattgact
     6001 ttttaaatca agatactata gctatttcta atgtagaatt ttgggtaaaa gagactaatt
     6061 ccaaatcaaa gtctgtagat ttagatttag aaaagaagaa aatactatat aaaagatata
     6121 ttaagctatc acaagatgcg aatagtgata ttgaatcaat tagatatatg gaggaagctg
     6181 taaatatagg taaaagtatg attactaaag aagataaaga acttggattt tggaaaggtt
     6241 tatctaccag agcctatatg atagcacttg aatcccttgc tagaaagtta gaaagtatta
     6301 ataatctaaa ggagtccaaa aaagtattag aatatttaat agaaattaat cctagtgatg
     6361 agcagggaat aagatacaaa ttattaaatg tattaattag attaaatgat agaacttcaa
     6421 taaataaatt atttgaactt tataaagaag aaaaatctgc tacatggatg tacagtaaag
     6481 ctctttatta ctttaaaaat aaaagtatgt ttttggcaaa tgattctatt aaggttgcta
     6541 gaagtaaaaa taagtacgtt ggattatatt tgttagattg gcgaaatgct tttggtagag
     6601 aatttgttac agaggaagaa aaggcagaag ctgtctatta ctatgatgaa aacatagtga
     6661 tttggaatga agttaaaggt tctatggatt ggctattaaa aaaaatgttg gaattttcat
     6721 aaaaaaaact actccttact tttatataag tcaaaggagt agtttttaat ttatacatct
     6781 agttttaaat cttcaggttt tattagacct ttttttctca taaattctga aatcaacaaa
     6841 gttacaatag caggaagtat aaaattaagt aaaaatatac caacccacat agatatacct
     6901 ccttttccag cactttgcat agcagttact gttccaaatt gtccaaccaa tccacaagta
     6961 cccataccag aaccaatagg aatattctcc attttgaata ttgttgtaga taatggtcca
     7021 agtaatattg aagctacagt aggtggtatc caaattttcc aattttttat tatattaggt
     7081 acttgcaaca tagatgtccc aagaccttgt gccacaaggc cgccaactcc attttctcta
     7141 aagctcataa cagcaaagcc taccatttgg caacaacaac ctacagttgc tgcaccacca
     7201 gcaagaccac ctaaacttaa catcatacaa atagctgcac tacttatagg taatgtaaga
     7261 gctattccaa caagtgcaga gactaaagct cccattatta taggttgcat agttgtagct
     7321 tgcattatta tatttccaaa tgaagtcata aaagcagaaa cagctggacc aataagttca
     7381 gctacaagta ctccaattag tattgttaca gcaggtgtaa ccaatatatc tatttttgtt
     7441 tcttttgaaa ctaattttcc aacctctaca gcaaaaagtg tagcgacaaa tgctccaaca
     7501 ggtcctccta attcattacc acaagctcca acaagtgcac aagaaaatag tacaagtgga
     7561 ggtgcttgaa gtccatacgc aatagccact gctatagctg gaccagtaac ctgtttagca
     7621 agagggctta taacttcagt aaaaagagaa atattgaaat tatctcctaa tgtattgaaa
     7681 attgttccaa ttaaaaggga cgaaaaaaga ccgagtgcca tataacttag tgcgtcaata
     7741 agataccttt gaacagaaat ttcaatattt tttcttttag caaatgattt gaaatttctt
     7801 tttttataat tgatttccaa tttaaaatcc tcctcatata atataagtat aatttctttt
     7861 taattaatta tataactttt cagctgacaa gacaaatgtt atttcactaa aattagacta
     7921 ttgtaatagt aagaaattaa cattaatttt agttttaaat tttaaattta tggtttataa
     7981 ttagtatagg gatattctga aatataataa ttttccagtt tatcccaata tttaacttag
     8041 gtagattgct tacaaaacaa atgattatat attaggctaa aaggaagtgg atagatgata
     8101 tttgtaaaaa ataagaaata cagaaaaatt gccataatta tatctattcc tatattgctt
     8161 gttgcgcagt actacctttt taaatttgga atacttagac caatggtaaa gggagtagaa
     8221 attgaaattg tagatgggga atatgttaaa gatatagata aatatgtagt aaaattaaat
     8281 gaaacagtta ctttgtctac aggtgaatat attaaggttc cttcgtatgc taaaaatcca
     8341 aatatttggt ttaatgtatt ggataactca gggactttaa aaatagatgg aaataaaatg
     8401 acagcattaa aggttgggta ttcttctgtg ggtatcatga aaaattcaag agtattaaaa
     8461 aaggctacta taaaagtagt agacccagag gtagaatcac tagatatgga gattaatggg
     8521 gatttaaaac atgttggtga tagtgctact atagaaagta caatagaagt tgattatgat
     8581 aagtttaaaa aatcatataa gccagtttat aagagtagca atgaaaatat tttaaaaatc
     8641 aaaggaaata aagtaagtgc agttggagtt ggtaaagcta caatatatgc taagtgtgga
     8701 aataaagaaa ttgagagaac atttaggatt caagctagag ttgctgaaat aaatatggat
     8761 gatataaaaa tagaagttga ccagaatgaa aaattgaaac cagatataat aacttctccg
     8821 cctggtttag aaccaccaaa aatatattat gagttagtag attcaaaatt acctgtagaa
     8881 agagcaataa gtttaagtag taatggaaat gttgtagggc ttagagaagg taaagatagg
     8941 gtgagaataa cttgtggaga taaatctaaa gtaataacag taacagtagt caaagaaact
     9001 ataacgaatg actatataca aaacttggtt ggttcacata aaatagtaaa caataaagtt
     9061 attattaaac ttgaatggga ttatatgaaa gatgtctttg attatgatat atatcttaaa
     9121 gataagttgt caggagaatc atttaagaaa attaaatcta taactataaa tgaaagtgat
     9181 ttaggtaagt ctaacaaggt atatgcaact atagaagtag atatgaaggg taatcaaaat
     9241 atagattttg atatttatgt catagggaaa aaggattcag atacaactaa gccaagtaat
     9301 gtaataaata ttaccaatgg aaatggaaat tcaaataatg ataataatat taaagatatg
     9361 agggtagaaa atatatcagc taatgttgat agagataata atgtcattag agttaactgg
     9421 agtagtatat ctcataagga ctgtacttac agtatatatg taaaaaataa tactaatgga
     9481 gatggagaat ttactctata tcaaagtgat atacagggaa atgagcatac tataagtatt
     9541 cctgaaggag atttaaatct agatatttat gttgttgcaa attataatgg aaatagctct
     9601 caaaatagtg atgttataaa tgtaagatag atttgtatac aaattgaaag tgttgagttt
     9661 atttaaatat taaattaaga aaaaggatag tatagggtaa ttatactatc ctttttttgt
     9721 tataatatat aggtttaaaa tctctagtaa tataaattat aaaaagtctt atttacacaa
     9781 atctatagat attcttttta ttaatcaata ttgtcttaaa ttgaatttag tgcagcttct
     9841 attgcatgta ttactgtcgt atcaaatagt ggaatagaag tgtcattttg tttaattaaa
     9901 agacctattt ctgtacatcc taatataaca gcctctgcac cttgtttgcc aagcttatct
     9961 ataatagata agaaagcttt ttttgaagat tcagatataa ttcctaagca aagttcatta
    10021 aatattgtgt catttactat tatacggtct tcttcatttg gaattaagac ttcaattcca
    10081 ttattaataa ttacattttt ataaaaatct tgttccattg tatatttagt acctaataag
    10141 gccacttttt ttatttcttt ttcccttaat accgtagcag ttacatctgc tatgtgaagt
    10201 aatggaatat gtatactttc ttgtatttta tctgatacct tatgcatagt attagtacag
    10261 ataacaataa aatctgcccc tgcctcttgt aatttaattg cagcatcagc taaaattttg
    10321 gcgctttttt cccaatttcc actagattgg cattcttcaa tttcttgaaa atctacactg
    10381 taaagtatac atttagaaga gtgtagtcca cctaatcttt cttttattac tgtattaata
    10441 acttgataat atgtaatggt actttcccaa ctcataccac caattaagcc tatagtcttc
    10501 atattatacc tctcttattt atttattttg aaatagctat ttacaaatac aagtatagca
    10561 tctaaaatag aagcatacaa tgataaaatt gtatggagta caattataat taagaggagt
    10621 aattatatgc caataaattc ttttgaaaac tatcctatga catggaaacc aaaattagat
    10681 aaccgaaaac caccaatata taaaacttta gcaatgttat tagaagaaga tattaaaaga
    10741 ggaaatttaa atcctggaga taaactgcct ccacaacggg aattagcaga ttttctagat
    10801 ttaaacttaa gtacaataac acgagcattt aaactttgcg aagaaaaggg actaatatgt
    10861 gcaaaagtgg gaaagggaac attcatttct tctgatgtaa atgtaagtaa tacattatta
    10921 tatcaaacgg aatcaaaaga cataattgaa ttagggacag ttcatcctcc atatgagcaa
    10981 aatacatata ttattgactt tattaaaaat gtactaaaac aaccagaaat ggataggttt
    11041 ttacaataca tgtctccatc tggcacatat atgcaaaaaa agtcaattgc aaaatggata
    11101 gaaagaaata atgtatacac cagtgaagaa aatatattat tatctacagg agggcaaaat
    11161 gctatatgtg caactttact aggattattt aaagctggtg atagaattgc tacagattct
    11221 ttaagttttt ctggaattaa gtcaatagct aaaatgatag gtattcaatt agtcccaatt
    11281 cctcaagaaa ataatgaaat atcgattgaa tatcttgaaa gttattgtaa aaatgaaaat
    11341 ataaaaggca tatatcttat accagattat cataatccaa cgacacatac tatgtctgat
    11401 ttatctcgta aaaagatagc caagatagca aagcaatata atataataat tattgaagat
    11461 gctataaata gcatttttag agatggtata caaactccca tattttcttt agctagtgat
    11521 aatactatat atatttttag tacatctaaa tttttatgtg ctggtcttag agtagcattt
    11581 gtagttgctc caaaacgata tatagaaaat ttagaaaatg cactatataa tatgaatcta
    11641 atggtttctc catttacagc agaaatagta caccgtttat tatattctcc tattatagat
    11701 aaaattatag aagagaaaag agatgcaatt atagaaagaa atgaagttgc tgataaagtt
    11761 ttgtcagatt ataatttgat tggtgataag aattgcagtt ttcgttggtt acttcttcct
    11821 gatgaattgg atggaaaatc atttgaaatt tctgcaaaaa atctaggagt tcaagtatat
    11881 tgtgctgaac gattttcagt aggaaactct acagttccaa aagcagttcg tatttgtgta
    11941 acagctccaa aagatgtaga agaattagaa aaagggctta atataataaa gtcacttctt
    12001 aagagttaaa tttattttac tattatttaa ttaaataaat aaaaaggcgg agaaatttat
    12061 tataataaac ctccgctttt attatttaat gaaatacttt actttttatt aaaaaattta
    12121 attttaataa tcttgaaaat ataatcgttt tatggtaaaa taattcttaa aaatagaaaa
    12181 aattaatcat ttgttaaaaa aaatgcataa tttattgtaa tttattgacg aaggttgaaa
    12241 aatattcata aatgtgcgaa ataacagaaa aaatgcaaaa attaattcaa tttcatttgt
    12301 tataaaatct atatggcaaa attaaatctg cctatcagaa tgatataaac acatcagaaa
    12361 ggaggacgct atcaaataat acaagtagtt aactttgata gcaaaaaatt atgaatgaac
    12421 aaactagaat atccttagag agagctgctg aattaaaatc aaaaattgat gattatattc
    12481 aggctagaaa aacgattaac agaggtcttg aaaaagaaga agagataaat aaacgaaaac
    12541 agaaaatatt aagtatctta aatggaactg aagaggattg gaataactac aaatggcaat
    12601 tatcaaatag aataacagat gtagatactt tatcaaaaat tataactcta actaaaaaag
    12661 aaaaagaata tataaaagag gttggtactc aatttagatg ggcaatatct ccatattatt
    12721 tgagtcttat agacccagaa gatatatgtg acccaataaa attactgtct ataccaacac
    12781 atatagagtt ggaagatgaa caagaagatt tggacccaat gggagaagag tatacaaacc
    12841 cagcagggtg tataactaga agatacccag atagattaat aataaatgta acaaatgagt
    12901 gtgctatgta ttgtagacac tgtcagagaa gaagaaatat tggacaacaa gattctcata
    12961 agtcaaaagc tattatccaa gaatctatag actatataag agaaaatgaa gaaataagag
    13021 atgtactagt aactggtgga gatgctctta cattaaaaga tgattattta gagtggattc
    13081 ttagccaact taaagagata ccacatgttg attatgttag attaggtact aggactcttg
    13141 ttacaatgcc acaaagaatc acagatgaat tttgcaatat gctaaaaaaa tatcaccctg
    13201 tatatataaa tactcatttt aatcatccaa tggaaataac taaggaatct aaagaagctt
    13261 gtgaaaagtt agcaaatgca ggcgttccat taggaaatca ggcagtatta ttaaatggaa
    13321 taaataatga taaatttgta atgagatgtt taaatcaaga attactgaaa ataagagtaa
    13381 aaccttatta tatattccaa agtaaacatg taaagggaac aaaacatttc aatacatcag
    13441 tagatgatgg tcttgaaatc atggagtatt taagaggata tacatcagga atggctatac
    13501 caacatatat agtaaatgct ccaaaaggag gaggaaagac tcctttgctt cctcaatacc
    13561 ttgtatcaaa aggaacagat tacgttatgc ttagaacatg ggaaggaaaa gttataaaaa
    13621 tggaagatga acctgctgta gatataaaga aacttataaa agaacaagca caggattaaa
    13681 aaaatattta aagtttataa aaagaaacaa ctttaaaata aaaagaaaat ggatgtcaaa
    13741 tttatatcaa tttgcatcca ttttttatta gttatttatt attttgttgt tgattaacta
    13801 attcaagata tccacttggg tggaagtaat atatctcaga agtattttca tttacaaagt
    13861 aaccaatatc accatctgca tctggtaaaa atacataacc attaagattt ttagctttta
    13921 atgcttcaaa atcactagca tttccttgat atatgtaatc aacttcattg ttgtatttta
    13981 ctaaaagttc tttagcttgt tcttgagtca atttagtatt ttggcttaca ggaacattct
    14041 tttgagaatc tgcataagaa gattcattta ctggtgcagt taataacaaa caagataaaa
    14101 ctaataaaga tataagtgct tttttcatac taaaaccctc tttcatgttt aattatataa
    14161 gattcattac ttaataatat tgtatgtttc ctataattaa atattaccat taaagagaat
    14221 aatattacag ttacacagct gtaacttttg attacaaaat cgtaattaaa ttgtattttt
    14281 attccatttg tattttatca tgtctacgat ttacaaactc acagaagtat atctttataa
    14341 cgcccatcac aggagcagat agaatcatac caggtatacc aaagaatcct ccaccaacag
    14401 taactgctag gattgtaaag aatgggctaa gacctagttg tccacctacg atttttggct
    14461 ctataaatgt aacttcaact tgttgaatta ttattaagta aattaaagaa gttaaagcaa
    14521 ttgttggatt ggagaataaa ttaattatta caactggtgc catacctatt actggaccaa
    14581 aatatggaac catattcatg acacccataa gtgtaccaaa taatagtgca tattcagatt
    14641 ttaaaaagta aagaccaatt ccagaaagta ctccaactat aaaagaatct aaaatcttac
    14701 ctgtaaagta tttaccaata tttaaattta agctttgaca tagttctatt ataaagtctc
    14761 catatttttt acctaaggaa atataaacta ctttttttgt aaacagtaag aatttttctt
    14821 tttctaataa tatatagaaa caaattataa aacctaaaag aaattgtact ataaattttc
    14881 caactgaaaa tgtagtgcta aatatcccac caagtgaacc aataagcaag ttactaaatt
    14941 taggcattac actcataatt ttgtcaccat actcttttaa tgtattaggg tcaactgatt
    15001 gtaaactctt gcctaagtcg aataaaaact gctctgtttt atctatgtat gtaggaattt
    15061 gagcaactaa atcagctaaa ctatttacta tggatggaac tgtaaataat ataaacgaaa
    15121 ttagtataac tatgagtaca ccataagtaa gaagtaacga atatattctc ttaaaattta
    15181 atttactttc taagaacttt actagtgggt tgaatatata tgctaataca aatgctatta
    15241 taaatggtgt tagtagtgac attaataaac ttatcactcc aaaaaaatat ttgtaattat
    15301 caataacttt aatcaagata tatgaaacaa ctacagtgag tacaatattt agataaattt
    15361 ttttatcttg caaaataaca caacctttct tatatttatt aaatttagat atacttaaat
    15421 ctaagttaaa gttaatattt atagcttatt atacaataaa aagcagtatt aatatagtat
    15481 gattaatatg aaattataaa
//
LOCUS       DAEQAF010000090        14343 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.093, whole genome shotgun sequence.
ACCESSION   DAEQAF010000090 DAEQAF010000000
VERSION     DAEQAF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.093"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            75..986
                     /locus_tag="KRN00_002920"
     CDS             75..986
                     /locus_tag="KRN00_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH1828776.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            1161..1658
                     /locus_tag="KRN00_002921"
     CDS             1161..1658
                     /locus_tag="KRN00_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBH1828777.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            2402..2764
                     /locus_tag="KRN00_002922"
     CDS             2402..2764
                     /locus_tag="KRN00_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBH1828778.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            2829..3446
                     /locus_tag="KRN00_002923"
     CDS             2829..3446
                     /locus_tag="KRN00_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBH1828779.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSIPDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            3443..3928
                     /locus_tag="KRN00_002924"
     CDS             3443..3928
                     /locus_tag="KRN00_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBH1828780.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            3971..4489
                     /locus_tag="KRN00_002925"
     CDS             3971..4489
                     /locus_tag="KRN00_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBH1828781.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFRVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTINCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            4625..5584
                     /locus_tag="KRN00_002926"
     CDS             4625..5584
                     /locus_tag="KRN00_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1828782.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKIFSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            5610..7313
                     /locus_tag="KRN00_002927"
     CDS             5610..7313
                     /locus_tag="KRN00_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBH1828783.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            7526..9628
                     /locus_tag="KRN00_002928"
     CDS             7526..9628
                     /locus_tag="KRN00_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBH1828784.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREDKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESTDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPNDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKNTSNNDAVENKLKNNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            9641..10081
                     /locus_tag="KRN00_002929"
     CDS             9641..10081
                     /locus_tag="KRN00_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBH1828785.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            10117..10920
                     /locus_tag="KRN00_002930"
     CDS             10117..10920
                     /locus_tag="KRN00_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBH1828786.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDKTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            10960..11556
                     /locus_tag="KRN00_002931"
     CDS             10960..11556
                     /locus_tag="KRN00_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBH1828787.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            11662..12525
                     /locus_tag="KRN00_002932"
     CDS             11662..12525
                     /locus_tag="KRN00_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBH1828788.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            12592..13581
                     /locus_tag="KRN00_002933"
     CDS             12592..13581
                     /locus_tag="KRN00_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBH1828789.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAINNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            13673..14284
                     /locus_tag="KRN00_002934"
     CDS             13673..14284
                     /locus_tag="KRN00_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1828790.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
BASE COUNT         5825 a         1363 c         2670 g         4485 t
ORIGIN      
        1 gattttattt atttaaaaat tagtatgatt aatttagatt aaataaattt aataatttta
       61 gtaggtggta atgaatgaaa ataaatagat taacagaaat aatagtaatt ctattaaata
      121 aaaaattagt aacagctaaa gagttggcag ataggtttga agtttctaca agaaccatat
      181 atagagatat agaaactctg tctatgtcgg gagtaccagt atatatgacg aaaggcaaag
      241 gaggagggat atctttaata gaagaatatt ctatagacaa ggctatattg tcaaaaaaag
      301 ataaagagag tttaatagtt gcactgaaaa cattacaggc gactaagtat ccagaaataa
      361 attcagtagt aaataaaatt ggctcaatat ttggagagca aaatttttca aactggattg
      421 aaatagactt tactgaatgg ggaagtaatt ttaatgaaga tgataaattt acaaaaataa
      481 aagaagctat tttaaggcgt aatactataa attttaatta tgtaaatagt ttgtcaagcc
      541 agacaaacag aactgtcgaa ccactgaagc ttatgtataa gagtaagact tggtacttgt
      601 atggattttg taaactaaaa gatgatttta ggatatttag aattagtagg ataaggaatt
      661 tatctataaa ggatgaagta ttttcaagaa agataataga agaagtatgt ttgaatgatt
      721 ctaaagtaat taaggaaaat actataacgt tgaaattgag gtttaaagaa aagatgcttt
      781 ttagagtatt tgatgatttt aataaggatt taataactaa aaatgaagat gatacatatg
      841 atgtaattac agaatttcct attggtgaat ggatttatgg atatatttta tcatttggtg
      901 acaatgttga agtacttgaa cctaaagatg ttagggataa tgtaataact agactaaggg
      961 agttgtctaa aatttattca ttataatata atgctagatt aaagatttta ttaaatatat
     1021 aatatcttgc atttagtata taatatctca ctgtgtttaa ttatattaaa aatatgacat
     1081 aaaggtgtcg tatattataa attataattg aattagttca aaataaaata gattaataaa
     1141 aacaaagtga ggtataaagt atgaattatg aaatagtaga gataaatgag aaaatagtta
     1201 taggaatatc gaaggagact acaaataaag atggacaagc ggtaaatgat ataggtgaat
     1261 tgtggaaaaa atttatgggc aaagggatat ataatgctat aaagggtaaa aagaatgaca
     1321 agacaatagg tctatataca gattaccagg gtgattttac aagtccatat agctttgttg
     1381 catgttgtga agtaaatagt aattctgata aagagaagaa tttagaagaa ttaaacacta
     1441 ataatactgt tggagaaagt attattagta aagttatacc agcaggtaag tatgcaaagt
     1501 ttgttatagt aggaggtcaa aaagaagtag gagatttttg gtttaagttt tggcaaatgg
     1561 attttgatag gacttatata agtgattttg aagagtatca atgtaatact tttgatacaa
     1621 agaaacaaga agttcatatt tacataggaa taaagtagat ttgttattac tatattgaat
     1681 gaagtattga gcatagtaca tttattatag atagttttat tatttataac tataagcagt
     1741 aaatctgtaa aagatttact gcttttttag taattaatag tatcagtatc actttgaatc
     1801 ttcagacata ttcttcattt aatattgttt attgataaat gatacttgta aatataatga
     1861 tttgttattt aatttaaaat atgaaaaaaa gtattataaa cacattagaa tacttctgga
     1921 tttatgggta tacaatttga aaaatataaa aaataatgta taaagctaaa tctaatttaa
     1981 tcgataatac atatagagaa atataattaa gtaaataaac aactatctat tagatattga
     2041 gaaagtcaaa tcctatatga atctacagaa atgattttaa tgaatctgaa aaattttttt
     2101 atacaaacat aaaaaaggta taaagttgtt ttattataat ttaattactt ttgataactt
     2161 tttatgtttt atacaattat atttttaata actcgtcaaa acgccaaaca tatattacaa
     2221 tagatatata agtttttttg ttgacaaatt atgttaagag aattaagtat aatatggcat
     2281 aaataattac ttttatttat caatgaaatg tatttattgt gtagcgaaaa atagtcagat
     2341 agtatagaca ataactgaag ataaaagcgt ttattgttgt acatatggag gagttagttt
     2401 tatggaaaat aaaattttga tagtagatga tgctattttt atgagaatga taattaaaga
     2461 agctctgagt aaaagtggct ataataattt aatagaagca aatgatggag aagaagcgtg
     2521 taatatattt aaatatgaaa agcctgattt gatgttgctt gatattacaa tgccaaaaaa
     2581 agatggttta gaggtgctaa gagaaataaa aaagttggat tcaagtgcta aggttgtaat
     2641 gtgctctgca ataggacaag agaatatgat tgtagaagcc ataaaacttg gagcgttaga
     2701 ttttatagtg aagcccttca aaacagaaac attagttaaa gttgtagata atgctttaaa
     2761 ataaaagtgt aaatatacac taatacaatg aaaagcaaat aaatgcaata ataaagggag
     2821 gggtttatat tataaattat ttagaacttg atgatgttca tatagatgct cttagagaaa
     2881 ttggtaatat aggctctggg aatgcaatta ctgcacttgc atccatgata aatagcaatg
     2941 tagaagtatt aatacctatg gtcaagatac ttgaatataa tgaagcgaca aatttgcttg
     3001 gtggtccaga aaacaaagta gtatgtattt tactcgatat gaaaggtgat atcaatggaa
     3061 tgtttatgtt tttgttggat gaatcaataa ctcaacttat gctaagttct ctttttaata
     3121 aagaagaagc ttttttagat gagattgagg caattgaaat ttcagcaatt aaggaaatag
     3181 gaaatattat ggcaagttca tatgtaaatg ctattgcatc tatgttaaac atgactataa
     3241 gtgtttcaat tccagatata tgtattgata tggttggagc tgttctaaat gtgcctatga
     3301 taagattttc agatgttggt gacaaagtct tatttataga aaataaattt aaaatgagtg
     3361 ataattattt tactagccac attttgatga ttccagaaat gagctcactt agagaaatac
     3421 tcgtgaggtt gggattagaa gtatgaatag agagatagta gtgaacattg cagatatgaa
     3481 gatagcctat agaccaaatg ttttagttac ttatgcactt ggttcttgtg taggagtatg
     3541 tttgatagat aaagtagctg gaattggtgg aatgttacac gttatgttgc catatagtaa
     3601 agatgctatt aacattgaaa ataagtgtaa atttgctgac acaggaataa atgagctcat
     3661 taaatctatg gagaatatag gtgcaaatag aatatatata aaagcaaaaa ttgctggagg
     3721 tgctcagatg tttttaggaa gtagcaattc agtaattgca agtataggac ataggaatgt
     3781 tgaggcagta aaaaaaactc ttttaggatt aaatattcca atattagctg aggacacagg
     3841 tatgaattat ggtagaacaa tacgttttta cactgagacg ggtgaattac ttgtagattc
     3901 aataaataaa ggtaagaaga aattataata tatatttcat agaaagtgta ttttaggagg
     3961 gaggtattaa atgagatttc cagatgaccc atatttagat tatggactaa ttgatgaagg
     4021 aattaagtat ctaaagttta gagtagatga gcaagacttt ggggttgaac ttgaaaaggt
     4081 aatagaaatt actggaaatc aagaaattat atttattcca gaactaccta catattctaa
     4141 aggcataata aatctaagag gaaaaattat tccgataata gatatgcgtt tgagacttaa
     4201 aaaagatgaa ttaatgacta taaattgcat gtatatagta gtaactgaaa taaaggactt
     4261 ggtagttgga tttgtggttg atagagttga tgatatagta agcttagaaa aaagtaaaat
     4321 atcacctcca ccaagagtta ctatagaata ttcggattat tttgtaagtg gcgttggaga
     4381 attagaaggt aaaataatta ctttactaga tttagagaaa cttttgacag ataaagatga
     4441 agttttaata gatgaattaa tcaatgggtt tgattgcact atcatgtaac atagggatgt
     4501 agttagagtg ttattataaa aagattgtga tgagaacatt taagaatata gtggtataat
     4561 tattaagtat aaaaatttta aatcattaaa atttgaatat attatgttta agagaggttt
     4621 gtatatgaaa aataagcaac agggaacaat tttagtcgtt gatgatagtg ttctgatgtg
     4681 tgacttaata gataaaacac ttacaaaaga taattttaag gttaaaaaag catttaatgc
     4741 aatagaggca aaagaattta ttgaagaatt tataccagac attattttgc ttgatataat
     4801 tttaccagat aactctggtt ttgagttttg taaggaagta aaatctaatg ctcgtacagc
     4861 agatatacct ataattttta taacttcaaa aaatacagat acagacatag taaaaggatt
     4921 tggtgtagga gcaattgact atatggtgaa accttttagt atgacagaat taaaagctcg
     4981 tgttatagct catcttgaag taaagaaatc tcaagataaa ttaaaaaaga taaataatga
     5041 actggaatct tctcttgaaa aattgaatag actcgttgta agagattatc ttacaggtct
     5101 ttacaatagg cgacatataa ttaatcagct tatggagcaa agaagaatta ataaatatag
     5161 tgaaacatca atatccctta tccttggtga tattgatgac tttaaggtta tcaatgatac
     5221 ttatgggcat gaagcagggg atttcgtgtt aacagtaata tcaagtataa taaaaaagaa
     5281 ttgtagacaa attgatactg tatcaagatg gggtggagaa gagtttttga taatgctcac
     5341 aaatactcca atagaaggtg ctaagatatt ttcagaaaga atccgtaaag agataaagga
     5401 gtttgatttc aactataaag aacataaaat aaagtgtact attacattag gagtagtaga
     5461 agtaaactca aatatatcat tagaagaaaa catatcctta gcagataaag caatgtatga
     5521 gggtaaaaac ttaggaaaag attgtagcgt agtgagtaca atgaaaggat taaaaaagat
     5581 ataaacttac tttatgaagg agtacagata tgaaaagaga agtaaagctt tctaaattag
     5641 caattgtatt gttgattatt atagtattgg ctgttctagc agggattttt tcttctattt
     5701 catcttataa agcatttgaa aaagtagaaa aaagtattaa tgatatgaat aatttgagga
     5761 ctcaaagtca gtatataaaa gatacaacta gagagatcag tgatgtatta agaagatatg
     5821 tatttacagg agaaaaaaag aataaagata tttatgaaaa agaattatac ggaaaaacaa
     5881 gagaatcagc tttaaacaaa ttagaaaaaa ttggtcttac aaagagcgag tcaaataaaa
     5941 tcttagaagc aaaagaaata tcagattctt tagtaccaac agaacaaagt gcaataaagg
     6001 cagtcgaaag taatgataag agtaaagctc aaagtataat ttttggtagt gactatataa
     6061 actcccaaga gaaaatggat tctttaataa atgaatttca agaggatata gttacccgtt
     6121 caaattccaa aattgtagaa gtaaaaaaag aattacaaag tctaatatta agaacaatat
     6181 ttatactttc ccttttaata atattgacaa taatagaata tacagtaata aaattaaaga
     6241 tagtgattcc tattaataaa gtagaaaaac acttttcaag aattgcatct ggggacttaa
     6301 gaacaagtat agacgttgaa gaaagtaaat ctgaaatagg gctattagtg agttctgtca
     6361 aaaagatgca aagtatgctt ttaaattaca tagaccttat agacagtaca ttaactagta
     6421 ttgcaaaagg agatttaaga gtagagatag accaagaatt tataggtgat tttaaatcaa
     6481 ttaaaatatc tttagaaagt ataataaact cttttaatgg tgatttttct gaaataaatt
     6541 tatcagcaga acaagttgca agtgcttcag aacaagttgc agcaggtgca caagctcttt
     6601 cacagggtgc tactgaacaa gctagttcag tagaagaatt agcttccacg attaatgaga
     6661 tatcagatgg aattaagaag tgtgcagata gtgctagtct tgcatgtgag gtatctgacc
     6721 aatctgcatc acaagttggt ttcggaagta gatgtatgga tgatatgatg acatcaatgg
     6781 gtgaaataag tgaaaaatcg agtgaaatat caaaaataat caaaacaata gatgagatag
     6841 cattccaaac taatattctt gcattaaatg cagctgttga agcagcaaga gcaggtcaat
     6901 atggtagagg atttgcagtt gtagcagatg aagttaggtc tttggctggt aaaagtgcaa
     6961 aagcagctca aaatacagct attctcatag aagaagctat taaaacagta gaaaatggtg
     7021 tcagaattgc taaagagact gcaaatgcat tggacttggt agtaaatggt gtagaaaaaa
     7081 ctactaatta tattaatggt atttcttcgg ctgtacatag tcaagaagta gcaattacac
     7141 agattttatc tggaatagag caaatttcca tagtagtcca aatgaactca gcaacagcag
     7201 aggaaagtgc agcagcctca gaagagatgt ctgctcaagc tcaaatttta aaagaattag
     7261 tagaaaaatt tcatctaaag gaaagtgaag taagagaatc atcatgggtt taaattatga
     7321 ggtgaatatt gaagtaagag aatcattgtg tatttaaatt atgagatgta tatatattga
     7381 aataagagaa tgattgtgta tttaaattat gaggtacata tagtgagata agagaatcat
     7441 caaggattta aattatgaga tgcatatata atagaaaatt atttgtaggt cgtaggtgat
     7501 aaatgtgaat tatattgaac cgagtatgag acaaatgtta gatatgttta tatttgagac
     7561 aagtttatta ctcgaacaat tagatgaaat tatgattcaa atagaaaaag agaaagtatt
     7621 tactcataac aacattaatg aaacttttag aataatgcat acgataaaag gttcagcatc
     7681 tatgatgggg ttagacaata tatctgcttt agcacatagt gtagaagact tgttttatgc
     7741 tatacgtgaa gataaaatag aagttttaga caatgaccta ttatttgatt tagtctttca
     7801 atcattagat tttataagaa gagatataga tgagttacaa tcaagaggtt gtatatcttc
     7861 tgattactct aattttattg aaggaattga agagtatgtg agtactttgg aattatcaag
     7921 ttctatgaaa tcaaaggata atgcaaattt agaaagtaca gacgaaaaag aagtaataga
     7981 ttcaaatttt gaatacaaag aagactctga tgtagtaaaa ataatctttg aacaaggttg
     8041 catgatggaa aatgtgagag ctttcatgct tgtatttgaa cttagagatt actgtgaatt
     8101 tatagatttt tatccaaatg atgtagaaac aaatgcagag tctacagagt atattaaaag
     8161 ttatgggttt tatatacaat ttgtagctaa agaggataag gcaatagttt ataaaactat
     8221 agaagataat ctctatgtaa aagaatacat aaatattagt aaaaaagaaa tagaaatgaa
     8281 aaatacatca aacaatgatg cagtagaaaa taaattaaaa aataataata aagtaagtaa
     8341 aagttatcaa aataactata cagaagatga gatacaagaa gatgttttaa atgaaaaaac
     8401 tgatatggaa aaagatagtc taagtgaaga aaatgaacat ttaccaataa gtaagcagag
     8461 tattatgagt gtaaatttag aaaaattgga cttacttcaa aatatagttg gagaaattgt
     8521 aattatggaa tcaatggttg taaatagcgt aaattctaca ggtgttgata tagataattt
     8581 caataaggca acaagacaat tacacaagct tacagatgaa ttgcaagata tagtaatgtc
     8641 tatgcgtatg attcaaattg ctggtgtatt tcaaaaaatg catagaattg tacgagatat
     8701 gaataaaaaa ttagataaaa atgtagagtt aataactata ggagcagaaa cagaggtgga
     8761 taagagtgta attgataatt tagcggaacc ttttatgcac cttataagaa atgctatgga
     8821 ccatgcaata gagcctattg aggagcgtat agcgaaaggt aaagaagaag tgggaaagat
     8881 agttttatct gctgaaaatc taggcggaga agctgtgata agtatttcag atgatggtag
     8941 aggcattatg agagataaga ttttggcaaa agctaaggaa caaggtcttc ttaaacatca
     9001 aagtaatgag tatactgatg acgaggtcaa ttctttgatt atgactccag gcttttctac
     9061 aaaagaatct ataactgaat tttctggaag aggagtaggc atggacattg ttcgtaaaag
     9121 tattgaaaaa gttggaggtt caattgaagt aaaaagtaaa caggatgagg ggacaacctt
     9181 tactataaaa ataccattaa ctctttctat agtagagggt atgaagttta aagttggaga
     9241 ttcactattt actttaccaa tatcatccat aagaagaaca tttaaactta cagacttaaa
     9301 tcaaataatt acagaaggaa ataagacaga gttaattaca atatatggag catgtattcc
     9361 cattataagg ttacataaaa tatataatat tcaaacaaaa gtaaccaatc tgatgaatgg
     9421 gaatatgata attattgaaa atgagcataa agcagtatgc atttttgttg atgaaataat
     9481 aggtaatcag caagttgttg tgaaaccatt tccagtttat tttaaccgat ttaatataaa
     9541 aaataagggt ttatcgggat gtacaatact tggggatgga agtataagtt taattataga
     9601 tgcagatagc attatagaaa tatattaggg gatttaaagt atggctaaag atgaaattat
     9661 taaacaagta ttaacatttt atgtcaatga tgttatttat ggaatagaat tagaaaatgt
     9721 gattgaaacc ataagatttc aatcaataac gtatgtacca tgtcttccaa catacataag
     9781 tggagttatt aatttgagag gaagaataat accagttatt aatatgcata taaagtacaa
     9841 tcttcctaaa gctgattata atgagagaac ttgtataata attacaaagg ttgatgagta
     9901 tcaagttgga attattgtag ataaagttgt tgatgttatt catatagaaa atctaaattt
     9961 actagagacg actaattcta acaacactaa tattaataaa gatataaaag agattgcgaa
    10021 agttgaagat aattctatat taattttaga tattcgaaag tttttgatta atagcatata
    10081 gttagttctg ataaattagc aggaggaagt ttttgtatga taaaactcac agatgaagaa
    10141 tttatagttc ttgtaaacca tgtaaaaaaa gaatatggta ttgatttaag taaaaaaaga
    10201 gcgttaattg aaggtcgctt atacaataca atgatagaga aaaaacttag ttcttttagt
    10261 caatatatga atctattatt taaagataag acaggaaatg aagctataaa cctaataaat
    10321 agattgagta ctaaccacac attttttatg agagaacctc aacattttga gtttatacag
    10381 aatagtatac ttcctttttg ggaagaaaat aataaaataa gaaacataaa tatatggagt
    10441 gcaggatgtt ctagtggaga agaagcgtat tcaatagcta tgactttgga tgattatttt
    10501 ggatataata aagagttgtg gaacattaaa atcatagcca cagatatttc aactaactca
    10561 cttgaaaaag ctaaaagagg tatatacata gaatcaaatg ttaacaatgt tcctgagtta
    10621 tggaagaaga agtattttat agacaacaag gatggtacat ttaaaatttg tgataagatt
    10681 agaaaaagtg taatttttaa gccatttaat ttaatgaatg atttctcata tcaacatttt
    10741 gatttgattt tttgtagaaa tgttatgatt tattttgatt taaaaacaag agaagaactt
    10801 ataaataaat tttataatgc taccaaaaaa gatagttttt tgtttgtagg acatgcagaa
    10861 gtaatcaaca gaagtagtac taaatacaaa tatgtaaaac ctgctatata taaacgataa
    10921 aaaggtattt ttgatatatg attttttgga ggcggtaatg tggaacgttt taataatatg
    10981 gttattgcta taggcgcatc tgtaggtggt acagaagcaa tacttgaaat tataaaagac
    11041 ctaccaaaat caacaccagg gattgttgta gttcaacata tgccagctat atttacttat
    11101 atgtatgcac aacggcttga caagcagtgt attatgaatg taagagaagc taagaataat
    11161 gatagagtcg aacaaggaaa tgtgttaatt gcacctgggg gttaccagat gaaattgtgt
    11221 acggataaac aaggatatta tgtaacttgt gaaaagggag aaagaataag tggtcactgt
    11281 ccatcagtag acgttttgtt tgattcagta gcagaagtag caggtaaaaa ttcaatagga
    11341 ataatactta caggtatggg ttatgatgga gcaagtggac ttttaaaaat gaaagaaaat
    11401 ggttcattta caattggaca ggatgaaaat tcttgtatag tatatggaat gccaatggta
    11461 gcttttgata gaggttctgt tatgttacaa ttacctcttg gtgaaatttc aaactgtttg
    11521 ataagacata ttaatatttt aaaacaaaaa gattaatttt ttataaataa aaattaatct
    11581 tttattaaat tatatggata aaaaacccta gaaactccaa atataataag agagatttat
    11641 atttaggagg aaaatgataa tatgaaattt tttaaagtcg atacaaaagc taaagtttta
    11701 agatatgtat ttgttttaac attgactata atggctgttt tggcaattaa acatgactat
    11761 aaatataata atttaaggaa agatgcttca attaatttaa atagtaataa ggaagcagtg
    11821 actgttatga gtaaccagtc attaccaaag ggtaatacaa atagtaaaca aactttatca
    11881 gtaagtacaa taggaagtaa aacaatagtg aaaaatgatg agtatttaga aagtactata
    11941 aacatgcctg taataacaaa ttcaaataaa attgttgaaa ggtctacaaa tgataagata
    12001 aaaaatgaca tatttgaatt ttataataaa tcatataaag aagcaaagca gtatcttaag
    12061 gataatcctg acgagaaaaa taagtttgtt gcaaatgtag actttgaact taaaaagaat
    12121 actgattctg ctcttagtat aaaagtgaga tattatactt atagtggtgg agcacatgga
    12181 ttttatcaag atatagcata taatgtggat atgagaactg gaaaattttt agaattaatg
    12241 gacttgttta aggataatac taaatataaa gaagttatag atgaagaaat taaaagacaa
    12301 atagctgaac ttgaaaaaaa ggatgaagaa aatataggaa tatataattt taaaggtata
    12361 aaagagaatc aaaactttta cttgcaagat gagaatctag ttgtatattt tgatttatat
    12421 gatataactc catatgcagc aggaatacca gaattttcaa taaataaagc gttgataagt
    12481 tctatgctaa aaccagagta tgtagattta tttgatttga aatagaagat taaattaaat
    12541 gttatgctat aatatttagc atagagactt attaaaattg ggggtataaa aatgctactt
    12601 ttaaaaaaag acgacataaa aaaagtattt acaatgagag atgcaattga agctgataag
    12661 gaagctttta gaatttattg tgaaggaaag agtgtaaatc ctttgagaac caatatatct
    12721 gttccaagtc aagatgctag tatgttattt atgccaggat acgtagaaga attaggctgt
    12781 gggggaataa aaattgtatc tgtatttcct aaaaatgctc aaaaaggcaa accagtaatt
    12841 ccagcaacag tactattatt agatggagaa actggagaag ttagtgcagt attggatggt
    12901 acttatgtaa ctcagattcg tactggagca gcctctggag cagctataga tgtattggct
    12961 aaaaaagatt ctaagattgg agctttgata ggtctaggag gacaaggtga gccacaactt
    13021 gaagccatga tagaagctag aaatttggat gaggtaagag tttttagtag aaacaaggaa
    13081 agtagagaaa aatttgcaga agaaatgaac ttaaaattaa gtaaatataa tactaaaata
    13141 gttgcagttg aatcatctga tgaagccata aataacgcag atgtgatagt tttagctact
    13201 ccatcaaaac aaccagtact taatggaaac ttagtgaaaa aaggagcttt aataagtgca
    13261 gtaggttcat atatgccaga tatgcaagag ttgtgcccaa actgtttaac tagagcgtct
    13321 aagatatttt ttgaatcaac agatgcagtt ttatctgagt caggagatat attaattcca
    13381 ttaaaagaag gtaagataag taaagatgat tttagtggtg atttaggaaa tgttataaac
    13441 ggaactattc ctggaagaga agatgatgat gagataattg tatttaaaac tgttgggata
    13501 ggtgtacaag atgtcgtaac agcaaaaaga atatacgata aagcaaaaga aaacggtatt
    13561 ggaatagact ggaagtggta aaatattcaa aataattcta tagttagaca aatttatgtt
    13621 ataatgttga taaataaatt ttttattatt ttaattgagg gaggatgttt gtatgaaaat
    13681 ggtaaaaaag ttaatattat ctacgattat ggctctagtt ttagttctaa ctatagggtg
    13741 ttctaatgca gaagaaaaag taaagtcgaa ttttgaagct aatttagctg cattagaaat
    13801 gtataagtat gatgaaaaag gaatttctga tgcattaaca gaagctgaat ataaacagat
    13861 tcaaacttat aacagcaagg acaaggtttc aatgattgct caattgacac ctctttatgg
    13921 taaagaaaat gctgaaaaga tatacgaaac aattgttaaa ttaattcaag gtgttgaaaa
    13981 gacagtaaca gtggaatctt ctagtaagga taagataact ttgaaagttg taagtaaagc
    14041 tttagatact agtaaagtaa tgagtgaagc gaacacttta gtaaaatctt atgtaactga
    14101 tgaaaagaat tacgataaaa aagaaaaaga agttcaagat gatatgacaa aaatgattat
    14161 agacctttac aataagaaac caactaagga agttacaact atgattacat atactaaaaa
    14221 agatggtaaa tggcaaccac ctagtaatat acaaaagtta tgtgaaggaa tatatacaat
    14281 ttaatttatt ttaaagacac aaaactatct tttaagcata taataaaatg tttggaagat
    14341 agt
//
LOCUS       DAEQAF010000091        14068 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.094, whole genome shotgun sequence.
ACCESSION   DAEQAF010000091 DAEQAF010000000
VERSION     DAEQAF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14068
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.094"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            402..1805
                     /locus_tag="KRN00_002935"
     CDS             402..1805
                     /locus_tag="KRN00_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1828791.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            complement(2206..3228)
                     /locus_tag="KRN00_002936"
     CDS             complement(2206..3228)
                     /locus_tag="KRN00_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1828792.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(3263..4861)
                     /locus_tag="KRN00_002937"
     CDS             complement(3263..4861)
                     /locus_tag="KRN00_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBH1828793.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYVLVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETPNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGIDKIDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            complement(4903..6168)
                     /locus_tag="KRN00_002938"
     CDS             complement(4903..6168)
                     /locus_tag="KRN00_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1828794.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAG
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            complement(6310..7707)
                     /locus_tag="KRN00_002939"
     CDS             complement(6310..7707)
                     /locus_tag="KRN00_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBH1828795.1"
                     /translation="MASINKNNVTSKEEEKEVSTSVLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKNKKVIFKGEDN
                     MSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDYIMKITHNIWE
                     EKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIGQNVIWSNFGA
                     DGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEWLVRDNLWIVT
                     QLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDDSVGEMMLEMT
                     SRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLLASIPNGSYEVERVT
                     CNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQGKVKEEWITF
                     DGMDVLKQMYMGVEE"
     gene            complement(7745..8752)
                     /locus_tag="KRN00_002940"
     CDS             complement(7745..8752)
                     /locus_tag="KRN00_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBH1828796.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDN
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            complement(8949..10271)
                     /locus_tag="KRN00_002941"
     CDS             complement(8949..10271)
                     /locus_tag="KRN00_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828797.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIDTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTKFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKLFLLF"
     gene            complement(10629..12269)
                     /locus_tag="KRN00_002942"
     CDS             complement(10629..12269)
                     /locus_tag="KRN00_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH1828798.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHISHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            complement(12425..13081)
                     /locus_tag="KRN00_002943"
     CDS             complement(12425..13081)
                     /locus_tag="KRN00_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828799.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            complement(13107..13808)
                     /locus_tag="KRN00_002944"
     CDS             complement(13107..13808)
                     /locus_tag="KRN00_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBH1828800.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
BASE COUNT         4787 a         2642 c         1667 g         4972 t
ORIGIN      
        1 aacaaatcct ataattatat tctaatatac tacctactac tttgtgctac aacaatttct
       61 ctatttatat gatttgtaaa atatagtaca acatttttta tcattttcat ttcaactaaa
      121 tttgtaatat tttattcaat acttaataaa tacttaataa atacatgctt tataatactt
      181 tactcaatat ataatcaata cataatttat aatttgtaat actttattca atacataagt
      241 agaaatctct atatacataa attcattttt tcatacatct tacaaattta tttttattta
      301 gataacatgt atattttttc catgaaaaat aaataataaa aaatagtaaa tatggaaaat
      361 ataaaattga ttaacaataa ttaattacct gaggtgtgaa tatgaaaatg ctaaacaact
      421 tttttaagaa aatcaacaat ccagctcctg tctttgcaca gacaaaaatg gaaagagata
      481 atcaaacaga tgattcactt tctacaaaac caaagactac atttagagac gttgctggat
      541 tagacgaagt aaaagaagaa ctatttgaaa tagtcgattt tatgaagtca ccacaaaaat
      601 atcaaaaaat gggtgcaaaa atacctaaag gagtattatt ttatggtcct ccaggaacag
      661 gtaaaaccct acttgcatct gctgtagctg gtgaaacaaa ctcatcattt ttcaatgtta
      721 ctggttcaga gttcgttgaa aaatatgtag gtgtgggagc aaaaagagtt agaactctat
      781 ttgaaaaagc tagaaaagaa gctccaagta taatatttat agacgaaata gatgctgtag
      841 gagcaaagag acatcttgaa agtaacaacg aaaaagacca aacactaaac caacttttag
      901 ttgaaatgga tggatttaat aaagattcca atgtattaat aataggtgct accaatagac
      961 ttgacttatt agatgaagct ttacttagac caggaagatt tgacagacac attcatatag
     1021 gtgcaccaaa ctatcacact agatttgaaa ttctaaaggt acatacagat gacaaaccta
     1081 tagacaaatc tgtaaatcta gaacttttag ctaaaaaaac tcatggtttc aatggggctc
     1141 atctttcaaa tatagcaaat gaagcagcta tatttgcagt tagagatgac agtgagtgta
     1201 ttacatcaga acattttgac aaggcacttg aaagagttat tgcagggtta gaatctaaaa
     1261 actctgcact ggttgaaaaa gagaaaaaaa tagtagcata tcatgaagct ggacatgctc
     1321 ttgtaagtga tatagtagga atttgtccta tacaaaaaat atctatagtt cctagaggac
     1381 aagcattagg ttatgttctt caattacctg atgaagatag atatatttat actaaggatg
     1441 agttgattgg aaaaataaaa atattacttg ctggaaaggc ttcagaagaa ttaatattta
     1501 atcataaatc tactggtgca aaggacgact taaagaaagt cactgaaata gctaaccaaa
     1561 tggtttgtga atatggtatg agtaacttag gatttatgac tattgatgga aatgataaga
     1621 ctttcttatg tgataaggtt caaaaggaag caaatcgtat agttgaaatt tgttataaag
     1681 agactttaga gatgttaaag gataatcttg aagatttaca ttctgtttct aaattcttat
     1741 ttgaaaaaga aactatgact catgaagagt taaaagattt gataggaaaa gaagctgtaa
     1801 actaatatag ttttaaaaat ttgaggctgt ctcaaaatag agataagcct ctttttattg
     1861 ttaaagttat aaaaatacat ttgattttat acaaaaaagt gcctcataaa ctaaaaattt
     1921 cattttgaga cacttacata ttttaattac atattttaat tttgtctatt tacagaatat
     1981 tatatctaca taaaactaaa ctgctgtaaa cttaactacc tccagtaatg tttgaagtgg
     2041 tataaaagct agtagcctag tttctacact tataatttat attttacata actaaattta
     2101 gtagattttt atactcacaa tttagaacga ttgaaaactt aaaaatttct tatcagatat
     2161 ctacaactta attaggtatc taccacttaa ttaaatatct accacttaaa gtgtagaacc
     2221 tctttcaatc aattcaggtt ttaacatttc aacaactgac tctggatttt cttcatttaa
     2281 taaggactta agtatgttaa ttgttttttc aatcaacaaa tctagtggct gtctaatcgt
     2341 cgttaaatta taactcttcc atgaagccat ttgaatatca tcatatccta tcactgataa
     2401 atcctctggc accctcaact tgtactcaaa ccttgcagca tccattacac caatagctat
     2461 caagtcactt gtgcaaaaaa ttgctgttgg aggatttgat aatgctaaca ttctcttacc
     2521 tgcttcatat ccagaatcat aatcatagtt tgcagattct tctttaaggt tatgaatccc
     2581 actttgtctt aacttagaat aaaatccaat tttcttttcc atttcttcac ttgtttctct
     2641 cgtaaattga atatatccta tattcttatg acctttctta agcagatatt cagcagccat
     2701 tcccccacct tcaattgggt ctacatagac tgtacttatt tttataccag gtataaaacg
     2761 attaaaaaga atcacaggaa tattgttttc ttcacaagtc tcagccatca ccttattcat
     2821 ggccgaagct gtaataatca cagcttctac ttgaaactga attacttttg aaattatact
     2881 atctatactt tgttgtctag gaactttaaa aacgagacac tgtttaccta tctcttgaat
     2941 tttttctaca aataaattga taattctatt gtaaaatgga cctagactat caccaactat
     3001 caatcctata acattagttt ttccactaat cattccccgt gctaccaaat taggaacata
     3061 tcctatttca tttgctacac gaaaaattct ttctcttact tcaggtttta cgccctttcc
     3121 atttgcacta ccaaatgctc ttgaaacaga tgattgagat actcctgcca atcttgcaac
     3181 atcttttgag gtagccgatt tattataatg aactttcttt tgattcattt agtatttctc
     3241 cttaaatatc tagtatttct tcttaaaatt gtatcaaaaa taatataata tattggataa
     3301 taaaaaaagc taatacaatt agttcttgtt tacctaaaga aaatggcact atagatactc
     3361 catctatttt atcaatgcct tgagaaataa ggtgatttct cataccaaat gcagtgtatt
     3421 ttttaatatc atctgcatta tgatttttct ttaaaatgac actaaaaata tatccaaata
     3481 tcaatgttat tgtagcacct attgctggat tccacaacca actcacatta tatttattag
     3541 aaataaaaaa tcctaaaact aaccctacaa taaaaccaat agatactcct ttatcattag
     3601 ctttatatgt aaacattgct agtacaaatg cacctgtagc tggtccagca aagtatgaga
     3661 tatagttacc aacaaggtca agaattgatt tgatgcttcc tccaaatccc ataataataa
     3721 aacctgtcat aacaactcct ataactacag ttataatcat tgtaactttt aatgatgatt
     3781 ctttgttatc ttttttgaaa taaaactcat aaatatcctt cgtaaaaaca gttgtcatac
     3841 tgtttaatat agagtcgata ctagacattg ctgctgcaaa cacacctgca ataataattc
     3901 caatggctcc tactggaagt tcatttaaaa taaaagtaat cattatttca tttggagttt
     3961 caaatgtcct tcccccataa aaaacaaata aaattactcc taccaatagc ataaagtagt
     4021 aaactaaatt cataacaaat gcactaacta caaaagaatt ttttgcacat tttaaagatt
     4081 tagatgttaa aactctttgt acttgagatt ggtcaaaaca aaagtatctt atccacatta
     4141 cagttccacc aattaaagta gcccaaaaag tatttgtcac tgaaatatcc ctactgaaat
     4201 caaatgtatt taattttcca ctctgttgtg caatttgtaa tgtatcaaag aaacttagat
     4261 tcattccttt taaggctaca ataattacta taaatacagc acttattact actatcattt
     4321 gaatactatc agtccatata actgccttaa tcccacctaa tagagtgtat ataattgaca
     4381 caagtacaac tattgggact aaaacataaa gtgaccagcc agtaatcatt tgaataataa
     4441 gcactggaat atataccata gaactagctt gaatcaatga attaataaaa aattgaataa
     4501 tagttaatcc tcttgaataa tttcctaaac gaagtcccat atattcatat atagaggtta
     4561 tttttaattt atagataact ggggtggtaa tgctcagtgc aaaaaatatt gctaaaggta
     4621 ctgtaatatt aaccattact ggatacattc catctacata tgcccatcca ggaccaccta
     4681 taaagccatt tgcactaatc atagtagctg caactgataa agcaattgga atccatggca
     4741 ttgacctacc tgccaagaaa taatcttctt gatttttatt atcttttcct gaataataac
     4801 caataactaa cattaatagc aaatatccta ttataataca tacatcaatt gatgaaatca
     4861 taagccaccc ctttctaagt aacaaaataa attcctagta ttttattttt tattatttaa
     4921 cgtctccggt aagaataacc atacaatagc acctgctaca aagactgcga ttgatatgta
     4981 aaagatagtc atcataccta aagtaccaga agctgtacca gctatagcag gtattgcaaa
     5041 cgtagatata atccttcctc cattaaatga cataccagat gacaacgaac gatatttact
     5101 tgggaacaac tctgtgtagt atgctcccca tgctccagaa tatccaacag caacacctag
     5161 taatactgat atcatataga atgttgttgt attatctcca cctaattttg tatatataaa
     5221 aacaaatact gctgctaatg ccatacctat aaaaggtatt tttcttccaa atttatctgc
     5281 aattgaaccc cagaataaat atcctactaa ttgaccaatt ccttgtaaac tatatataga
     5341 cccagccact gctgctgaca ttcctattcc tgtcactagg tatgtagttg cattatttga
     5401 aaatgctgaa tatgctgtaa aatttgcacc tgataaaaga atcgttccca atccaatcca
     5461 taagtatttt cccttataca tacttatata gctaatcttt tcaccagttt cttttccctt
     5521 tttaactaat tcctttgtat actccaaatc atctggcaca aagaaaattg ctaagatagc
     5581 tccaactata ggtggtataa tcgcagtata catcaatatt tgccaatttg catcacctaa
     5641 aacgccatat actttcccac caaaaatcat tgctaatgaa aataaagcag ttaatatagc
     5701 agctaactta ccacgatatt tacttggaaa catatctgca actaaaggca tagctgttcc
     5761 aaatacgcct cccaacacta ctcctgtaca caaacgtgct attttccata acataatatt
     5821 tgtaggagat aacattggta taaatgttgt caatccaatc agtaaagcaa cgctaattaa
     5881 agtcctcttc ttcccaattt ttgtagaaat caccccaaaa ataaatgtac ctggaattgt
     5941 accaaaagac ataactgcaa atatttcttc tgtttgtttt aatgaaaaac caaatccccc
     6001 atctgctaaa gcataaatca ttgttggttt aataaaagta cccaccataa aattgtagca
     6061 ataaaaaaag tatattaaag caattgaaaa aaatgcaatt cctcttttta ggtttgaata
     6121 gtcttttcct aatatgatat cattttctat ttcaaccgtt gttttcatat ttttataatt
     6181 ccccctttta aatttagtca taattttgct aaaagtttaa acatctattt ttcatatata
     6241 ttccccactt aaattttata aagcaatact tccctatata tttcaaaact atttatactc
     6301 taaacagctt tattcttcta ctcccatata catttgtttt aatacatcca taccatcaaa
     6361 agttatccac tcctccttta ctttaccttg tagtatatga taatgattga ttcccattac
     6421 ttctatatgc tttccagaag gctgtccaaa aaatcctata ccttcattta ttccacgtaa
     6481 tctccatctt acagatacat cataaccttc atttttttct ctttgattac aagttactct
     6541 ttccacttca taacttccat ttggaattga tgcaagtaaa cttacaatca ttccttgaat
     6601 ctcatcataa ccatttaaat ctttatcaca tataaaatgt actactgcat tatcatgata
     6661 gtatttttta acttcattta tatatttata attataaata cggcttgtca tttcaagcat
     6721 catttcgcca acagaatcat cttttgcttg atacttagtt ggcataaatt gaccatccat
     6781 agattcacag ataccataag ttgattgtaa actaagcact ttagattcac ttgcctttgc
     6841 catactcttt gctacttcct gagggtttaa tcctaattga gtaacaatcc ataaattatc
     6901 tctaaccaac cattcttcgt ggattctatt gttagttgtg gcacaatcaa ttacagttct
     6961 aaagtttatt tttctacctg ttgctggtcc aaaattacta tcacctaagt tagttgctgt
     7021 agacaaaaca cggtgagaag ataaaaaacc atcagcacca aagttagacc atattacatt
     7081 ttgaccaatt aatcttctat caggaaacgc atgtaatgtt tgaagagtat tggaaataac
     7141 atctttaata ccaactaaat ttgaagagcc acaatgcatt gtaacattat tgtgatatgt
     7201 atcataaata acacctatac ctttttcttc ccagatatta tgtgtaatct tcataatata
     7261 atctacaaaa tctctatact tagaatcaaa tccaggtatt tcctgttccc tttttgtctg
     7321 ctttgaaaaa tcattgtaat ccattactcc aacaggcgtt acttctaatg aatctccata
     7381 gtaaattttt gtagatgaca tattatcttc ccccttaaat ataacttttt tatttttttc
     7441 agtaagagta tttgtattta atttatctgt atccactgta tctatgttaa ctttatttat
     7501 gtcggattta tttgtgtttg ttttatctat atttccttta tatgtgttcg ttttattctc
     7561 atttgtttga ttttcattta tattactaaa attagtttga ttcattttag ctttgttttc
     7621 tttaaccgta catgattcaa gcacacttgt agaaacttct ttttcttcct ctttacttgt
     7681 tacattattt ttgttgatag atgccacttt atatcctcct ttgttttaga atacgtatgc
     7741 gtaactaagc attaaaaata cttttagttc tctcaagaat atcaagccct tgttgtttca
     7801 accaataagg aatatcaatt aacacccagt tttcttgaag tttatcgccc ttacgataat
     7861 aaacatcaac aacttgcata tctgctttaa cctctccacc tggtaatcct aaaaaacctc
     7921 cacatggtac attagtcaga ttaggccatc caaagaaaca agcaaaatta ccttctgcaa
     7981 atctacatac atgcccattg aaagtctttc cttttaaatt atttctaaat ggtagctggt
     8041 gttgctcttg atatctaggt atagtataag aagcaccaat tccacctgga ccataccaaa
     8101 tcatatcttt agcccaagat ttttcaagta tttctggtgg gcatcccata gcaccacttt
     8161 catttaattc agataaatca tctaccattt tatttactaa tgctaaagtt tttactcctt
     8221 caacttcatc tgcatcttca aaaagtaatc cattatggtc aattggccct ggatatacaa
     8281 aatatgaacc tgtttgtggt ggcaatggat taactcctgc ttgaatcata aacccaatta
     8341 tatctacaaa taatccagtt ttagcaattt taccatcttg aacacagtta aattctgcat
     8401 atcttaaact aatcatttta cgagtatgtt taatgccaag ccaatcatta tcaaaaagtc
     8461 ccataaaatg ccccatactc attacccatt cactattgtc aatctcattt gttcctgcaa
     8521 tgaaaatatc ttgtcgtctt tgcatattac tcaatgattt ttttaaaggc ttccaaaata
     8581 catctgctac attttcagtg ccttcttgtt cacgaaatgg atacacacct ttccagttat
     8641 aatctgattt catatgttgc tttaagacat tttcaacctc atccccagta gcattttcta
     8701 atgcttcaaa ataatttctt acaacttttt ttgaatcctg atattttccc ataattatct
     8761 cctcccagat ttatttaagt tataaattaa ctttcttatt ttatgcatac gatttccttt
     8821 ttaatgattt tttagctgtt ttaagtttat tttatgaata catatgcatt tttctaaata
     8881 ttaacatata tctaaaaaat tgtaaagaaa atgttatcat aaaaatttaa tttttgactt
     8941 atatctattt aaaacaacag aaaaagttta aaacgtaata ttctactggg tctaccatac
     9001 ttgctcataa gctgttcact cactacctca caataaccag aatcacacaa tctaagtata
     9061 atcctgtcca tagttctaat acttacacca catatagtag ctaattcctt tgatgtaaat
     9121 ttagtttttc cactatttat tattttattg aacactttat atacagtatt agcacttagc
     9181 cctgtctctg tagcaatttg ataaaaacgt tcatcaaaac tatttttctc tttgacagta
     9241 ggatttggct ttagtggtcc cataatttct ccattttcaa aaactacata tgctgcatca
     9301 tttttttgac tttgagccat cttaatactc tcataagcgt taaatttagc ttcatttgct
     9361 gtttttccat aaccaattcc tatataagtg tttataactg aaacttcacg aatcatatcc
     9421 aacaaataaa tatctctgta tttctttgtt tctaactcaa gtattttttt agttgtaaaa
     9481 atcataaatt cacttctact ctgctctacc aaaacaccat ctatacggct attgaaatgg
     9541 tatagtttat caagaatctt aatcctttgt gaaagataag cgtactcatc ttccttcatt
     9601 agtgaatatt ctgaaggcat gttcagttta atagcaagaa caataatctg attctcattg
     9661 tttttctttg caatataacg catctgaatg ttttttatac tttgcaccat tacgtcctca
     9721 gaaggcaagg ctaaaactac tggaatatta tcttttttca ttatatgata ggcctcttca
     9781 agacctgtaa tacaacaaca tacatcatta ttttgataat tatatttatg aaattcaagc
     9841 acaaacttta tatagtcctc ttctaaatac ttttgctctg caaaaaacat atgttcatcc
     9901 ttaaattcaa ctccaatttc tttatacaat ctcttcatca tagccttatc ataagtatct
     9961 atactaagtc tactaatatc gaatttaagc aaatatgtaa tttcaagcaa cactctgtac
    10021 aatgttgttt catgtctagg aatataatca gacaatacaa aatctttttg tcttttttca
    10081 aaaaatttaa atggcgactt acctgtaaaa agaactgcat ccactctacc tctatatttt
    10141 tccaataaat caggtacttc aatatatcta tcatatctaa gaaaatctgc ttcaatatta
    10201 ggaaaattct ttttacttac tgctagtatt ttatcgatta ccatacctgg tcctacataa
    10261 agtattttca tttcgtctct cctttcctaa tgatactatt atctcttaaa acattttcta
    10321 aacctaccat gactaaagcc acaggactcc tgattcatag aattttgaat aatcaattat
    10381 acctaatata aaaagttact ttaagttttt taattacgac tatctgttga aacatttttg
    10441 tatttaaatt tttgtattta aatcttattc attaatatta attacatttt acaattaata
    10501 tattgttttt tctacttaaa gttaaattct ttagaaaaca caagtagagt aatctttatt
    10561 aatttaacaa aaatagcctt ccttaatatt caaagaaaga ctatttttat aaaagttctt
    10621 aatgtattct attttgctat gctaagagga tttttaatta cacgtccagc acatacatca
    10681 gtttgctttc ctcctgccaa tgcaatttta ccattcacca acacatattc cactcccact
    10741 gtatactgtt taggattact ataagtcgct ttatcttcta ttgtatctgg gtcaaatacc
    10801 acaatgtcag caaaataatt ttctttaagt agaccccttt ctttataaat gcctaagcgt
    10861 tttgctgaaa gataagttat ctttttaact gcttcctcaa aagtcaacat acctttttct
    10921 ctaacatagt aagagaaaat tcgtccaaaa gtaccaaatg cacgaggatg aggctttcca
    10981 agagaaagta aaccttctgt agaaaggtcc atactatcag aacctataca tgactttgga
    11041 tggcaaacaa ccttatctgt atcctcttga ccttgtgtat gaacaactac ttgaatttta
    11101 cttttttctt caatcaaaag cctaaagaac gtatcaaatg gattttcacc attgattttg
    11161 gctacctcca ttaaagtttt accctctaca tatttatttg cttcagtcat tacagaggct
    11221 agtacaacac cgttccaccc acctgctaat tggtagaaac attgccatcc aggaatccct
    11281 tcctccaact cttttataat tctgtctcta ttttcttgta cttctaatcg ttttaccata
    11341 ttttctacac cgccttcaaa agcccaagga ggtaaaagtg cacccaaaga tgtcattcca
    11401 gctgtatatg ggtaacaatc aaaagttact tccaaaccat ctgcctcagc ttcatctagc
    11461 tttttaaata cctcatcaat agttccaaaa ttcttatgac ccataacttt taaatgagaa
    11521 atatgtagag gaactcctgc agtcttagct atataaattg cttcatcaag agcttccatt
    11581 tcttcatcac cttcatctct aatatgagat atatagtatc cattgtatgg tatcaattcc
    11641 ttacataatt cagccatttc ttctttcttt gtgtatgctc ctggtaaata aactaatcct
    11701 gatgaaagag ctacacatcc agcttccata gcttttctaa cttccaactt catattttta
    11761 agttgctcta aagtagctgg ttcctttgaa aatcccattt cattgatacg tacaggtcct
    11821 tgtgctacat aagctacaac attgactgct ggagaatttt cagttaagta atcaaagtat
    11881 tcttgcattg tattccaatg aagctctaat tttgttggaa ttgtaccaat tatcctagtt
    11941 ccaagataat caattaactc ttgcttcttc tcttctctta tcggagcaac tcctatacca
    12001 cagtttgcaa taacatctgt tgttacacct gtatggatac ggcttcttgt gtatttatca
    12061 tacacaagag ataaatcaga atgagtatgg aaatctataa aaccaggtga tacaaatttt
    12121 ccagttgcgt ctatagtctc tttagcctct ttttgactta aatctccaat agccatgatt
    12181 ttgtctccta caatccctac atcactttta tatcttgaat ttcctgtacc atcaacgatt
    12241 attccattga caattttaac atcaaacatg ctttttctcc tttcaagact tatttatatt
    12301 catatttctt aataaacaat cctattcttt tttctcaaca aataattcta gtctttctcc
    12361 ttaataaaca atcctattct ttttctcaac aaataattct agtctttctc cttaataagc
    12421 aatcctattc ttttgtttta ttgttatcaa ttacaaagaa gacccttgtg ataagtatcc
    12481 cacctaacac aataaacaat gttaataatc cacctggtat accaattttt tcaccaaagt
    12541 acataattgc taacgctaca gcaatcgtac atccaccagc tcgaatatcc ttacgtgcaa
    12601 tatcaacata aattgctcca aataatgctg gaagtatata attaaatgaa ttagtaacaa
    12661 attcaggtaa caaaggaatt actttatagc ctacaatggt aaaaatggta atcatagaag
    12721 ctgatacaaa gattgaacaa catgtaccaa ttgttccaac aacttcaccc tcatgagttc
    12781 ctgcttctac acctgcaatt ttctgtgcca ttgatgctgc aggcatacgt atatctccaa
    12841 cagaacctgc aagccaacct atataagaac ctggagctcc tagtgtagga taataagcta
    12901 taggttgaac aatccaacta accccataag tcgcagcgac taacccccaa atttgaaata
    12961 taacagaaag cattggcatc tgaccaaagc gaatacctac atagatagcg ggaataaagt
    13021 ttgcaataat tgcaagacct atagaaattc ttcctatttt tatcatcttt ttatcataca
    13081 taattatcac ctcttatccg ttttaatcac gataatataa tctgtgtacc aaacatacca
    13141 attaacatgg caatacctaa ggataattct tgtaatcgtt gattcttttt aaataaagtt
    13201 gtcaatacta gcataactat agctgaaata attgctggtg taagttttgg tatttcaaat
    13261 gtttttattt gatttgaaag aaggtaagca aataatccaa ctgtagctcc tgcaagtagt
    13321 tttttaaccc aagtaggatt atacttcatg ttcatctttt caacaattcc acgcattcta
    13381 tgacccaaaa taaatacaac aaatagccaa cctaagttat ttaaagccat cccccatagt
    13441 gcatacgaaa aagcttctgc tccaaatgca gcactaccta cttctacccc agataaattg
    13501 gatgtaagag atattactcc aagctctgtt ctagctgctc cgacatcaca gagcctcatc
    13561 caagtcgtag gagcgccaat cacagctacc agtgataata atgtaataac aggagataga
    13621 gaaggtccaa tggctgtaac actagctgag cgaattgctg ctttaattcc tttcctttca
    13681 ataccaagat ttgaagcctc ttttagtgcc tctttcataa atacgattgc ttgaacaact
    13741 gaaataatta ctaaaaaact agaaacaatc caaagacctg ggctattaat catttcttga
    13801 aacttcatac tttattcctc cttaaaataa atttttcagc attttattgt gagctttctt
    13861 tctgtaatct tgttatgttt ttatattgtt ttaatttatt ttatctaaga tatagtatct
    13921 ttaataggag attatctgtc ttaaagtctc actaaaaaca ttaatactta aatattttat
    13981 tcataattag taaatatcag aaaattcaca tattattttt ttaacctgta attaacttat
    14041 aaggtctttt attattttga catttcaa
//
LOCUS       DAEQAF010000092        13982 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.095, whole genome shotgun sequence.
ACCESSION   DAEQAF010000092 DAEQAF010000000
VERSION     DAEQAF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13982
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.095"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            201..341
                     /locus_tag="KRN00_002945"
     CDS             201..341
                     /locus_tag="KRN00_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828801.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(516..836)
                     /locus_tag="KRN00_002946"
     CDS             complement(516..836)
                     /locus_tag="KRN00_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBH1828802.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(956..1693)
                     /locus_tag="KRN00_002947"
     CDS             complement(956..1693)
                     /locus_tag="KRN00_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBH1828803.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            1908..3731
                     /gene="acd"
                     /locus_tag="KRN00_002948"
     CDS             1908..3731
                     /gene="acd"
                     /locus_tag="KRN00_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBH1828804.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            3946..8244
                     /locus_tag="KRN00_002949"
     CDS             3946..8244
                     /locus_tag="KRN00_002949"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBH1828805.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIVQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            8448..8909
                     /locus_tag="KRN00_002950"
     CDS             8448..8909
                     /locus_tag="KRN00_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBH1828806.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EKGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            8939..10093
                     /gene="nusA"
                     /locus_tag="KRN00_002951"
     CDS             8939..10093
                     /gene="nusA"
                     /locus_tag="KRN00_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBH1828807.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            10100..10381
                     /locus_tag="KRN00_002952"
     CDS             10100..10381
                     /locus_tag="KRN00_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBH1828808.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            10371..10682
                     /locus_tag="KRN00_002953"
     CDS             10371..10682
                     /locus_tag="KRN00_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBH1828809.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            10704..12644
                     /gene="infB"
                     /locus_tag="KRN00_002954"
     CDS             10704..12644
                     /gene="infB"
                     /locus_tag="KRN00_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBH1828810.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            12687..13067
                     /gene="rbfA"
                     /locus_tag="KRN00_002955"
     CDS             12687..13067
                     /gene="rbfA"
                     /locus_tag="KRN00_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBH1828811.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            13048..13725
                     /locus_tag="KRN00_002956"
                     /pseudo
     CDS             13048..13725
                     /locus_tag="KRN00_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT         5589 a         1591 c         2622 g         4180 t
ORIGIN      
        1 tatataaaaa agataataat agttagattt tttatatgaa ttttaatagg taaaatatcc
       61 tattgttttg tagatatatc ctaattatgt caaaaaataa aaaaaatttt atttattaga
      121 gtttttggaa ataataataa cagatattat aattaattaa cagtttttgt aagtatttga
      181 caatagagag ggtgtaacaa atgggaataa tagagtcagc atcaaaattg gctgagatgg
      241 ttcatttatt ggctgttgaa aaggggataa ctgatataga agcatgggat gaagctgtga
      301 aagaatacag caaaatttat gaagaaagaa gaaatgaata gaatgataaa aaatgaaaac
      361 ttgatgataa aaaataactt tatttaaaga aattcaattt ttatagaagt attaaaaata
      421 atataaataa aaagatggta tttcaaatgt aagtaaaaaa tcattttggg ataccatcct
      481 tattatttat tttaataata tataagtaat aaatcttact tatccatatt ttttatgtaa
      541 cctctttttt ctagcttttt tatatgctcc ttacgtattt catcaagatt aataccatat
      601 tgttcttcta gcttaaacat catagtaaca catgtctgcg ctacatccat tagttcctta
      661 gcagttttct ttataatatc aacttcatct aaatcattat tttctccact tagatttctg
      721 aatttaccta tacattcagc taattcacct tgttcttcac ccattttgat aaatgtagat
      781 tctagtgttg ggtctaaatt attaagctct ggtaaagata tagtttttag tttcataaaa
      841 gctcctttca agttattcgt atttatacta aaacatcata acaaaaataa tactaaaaaa
      901 aaactttaaa ttcaacataa aaacttacat atataataaa aatcgtgaaa taaatctata
      961 tttgtcttaa tacagcctca tataaaactt ctccaatagg tttatttatt acaagagaag
     1021 ctgacttatc atagactgta tttgctttat taataagagc aatataatca cctttgtaat
     1081 aatctataaa acttgctgct gggtacacag ctaatgatgt acctcctata atcaataaat
     1141 cagcattact tatagcagaa attgttttag taatgacatc actgtcaaga gcttcctcat
     1201 aaagtactac atctggtttt actatagaac cacagttgtc acagtaagga atattacctc
     1261 ccagatttaa catagattct aagtcaaaaa acttaccaca tttagtacaa taatttctat
     1321 gtacagaacc atgaagttct agcacatttt tacttccagc catttgatga agtccatcaa
     1381 tattttgagt tatgacagct ttaagcttac ccatttcttc gagttttgct aaagctatat
     1441 gagcattatt gggttttgca ttaggatata ttaatttatc cttataaaat tcaaaaaatt
     1501 cttctggata tctaacaaaa aaagtatgtg aaactaattg ttcagcagta aattgtttat
     1561 tgagtttttg gctaaataat ccagtagaac ttctaaagtc tggaatatta gattcagttg
     1621 aaacacctgc tccaccaaaa aatacaatat tattgtgatt agctattaag tcttttaagc
     1681 tatttgcatc catagttaca cctccaaatt attatatata aattgtacta catattaggt
     1741 cgtttatgtt ttattaattt aaataaatat atagtttaat aagttaaata aagggaatat
     1801 aaataaaatg tatacagagt ataaatagac aatatttact aaaataacaa gttgtcgtat
     1861 aattatatta aaattgtttt agtgtataag aagggcgggg gaagtacgtg aagaaaaaag
     1921 cagctttagc aacattggct atgttaccct taggtgtggt aaatgcacat gctgatggag
     1981 atataggtat agtgactata aattatttaa atgtaagaaa tgaaccaact gccgaaagta
     2041 gcatagcctt tgttgctaaa aaagatgata aagttttgat taaagactct tctaatggat
     2101 ggtataaaat aaaagctgaa tctggacaag aaggttgggc ttcatcaaaa tatatagcaa
     2161 aatcaaatag tgactcttta agaacgtcta caaataaaga aaaacaagtt atttcaaata
     2221 gtttaaatat gagaaatgga gcaggtacaa gttacagagt aataactgta ctaaaaaaag
     2281 gtcaaaaagt agaagtaata tcagagagta atggatggtc taaaatcaaa tatgatggaa
     2341 gactaggata tgtatctagc tcttatttag gagacgtttc aaactcaact aataaatcaa
     2401 aaactaaaca agtgaataca acttcactaa atgtaaggag tggaccaaat acaagttatg
     2461 gtttgttagg caagttgcca aaaggaagta aagtagaagt aatatcagaa agtaatggat
     2521 ggtccaaaat aaagtataat ggaaaagatg cctatgtatc tagtatgtac ttatcggatg
     2581 taagtcaaag taattcagac aattctagtc aaagcaatga taaaaagaat actgataagg
     2641 ttgtaaatac agcttcttta aatgtaagaa gtggaccagg ttctacatat agtaagttgg
     2701 gaaaagttta taaaggaagt aaagtaactg tactatcaga aagtagtgga tgggctaaga
     2761 ttaattttaa caataaagaa gcatttgtag taggcaatta tttatctacc tcagcagata
     2821 cttcaaataa taactcaaat agtaactctg ataacagttc taatagtaat ggtaataatt
     2881 cttcatcatc aggccaagta aatggtatgt caggtataag tggggctaaa attgattata
     2941 aatctttgag ttatacttta gaatctcata taagtaaaca agttgagaaa gcagcatcag
     3001 gaggaaatgt gatagctcca agtaatagga aaagtactcc aagtcctgag tttagtactt
     3061 tttcagctca aagaacaagc tcatttgtaa atgcaagttc aagtgatata gaatattatt
     3121 taaatcctaa gaattttaca aatactacta aaggtatgat gcagttttta aagattaaca
     3181 gttatagaga tggtatttca gaatcaagtc ttaactcgta tcttaatggt ttatcttcta
     3241 gtgtatttaa aaaccaggga gcagccttta taaatgctgc caagaagtat aatatagatg
     3301 ttgtatatct agtatctcat gctatgtggg aaactgctta tggtaagtct acacttgccc
     3361 aaggtcaaac attaacatct tataagggac aacctcttag taagccagtt aaagtataca
     3421 atttttttgg tataggagca atagataaaa gtgctaatgt ttcaggtgca gaagcagcgt
     3481 attccaatgg ctggactagt gtagaagcta caatagatgg ctctgcaaag tggatatcac
     3541 aaaattacgt aaatagttct aagtacaatc agaatactat ctacaagatg aagtggaatt
     3601 atgattatac atggcatcag tatgcaactg atgtaaactg ggctaatgga atttctggaa
     3661 ttatggaaaa tttaattggt ctttatggag gaggaagtag tttggttttt gaagttcctc
     3721 aatataagta atacataaat aaaaaatata gactatgggt agttttcatt ttatttaaat
     3781 tatctatagt ctttttgtat ataatttata atctgtaaat ttaatgttaa caaaactttt
     3841 atgttataat attaattcta agtaaatata agtgagtaat aggtagaaat agataaaaag
     3901 tggtaataat atatataaag ataattttga gaaaggagga tatatatgga aagtattaag
     3961 gaatatttgg ataagttaga aattaataat agtggtcttg gaaagcaact taaagaagtt
     4021 tatataaata gagtagttta ttttaaggaa gataagatag tttattttta tctaacttct
     4081 aaagatattg tttctcatga acttttagat aaatttaaag aagaattgat gtataaactc
     4141 gattatttta aagatatgag gatgaagata agatttactg gtcttgaaag aaaatccaat
     4201 aaagatgtta taaaaaaata ttggaataat atattgtata tattaaagta tctttgtcca
     4261 tctattgcag ggtggtataa acaagtagaa tttctttgtt tagaagaaga attaaaaata
     4321 aaacttccaa aaggtatatt ttatgagcga ttaatgaaaa aaaatgtaac ttatgtactt
     4381 aaaaccgtgc ttagcgaaga gttgggatta gatttaaata taacaataga aaaagctgtt
     4441 gatgaaaagg taaataaaga aagactcata agaatcaatg atagagaaat ggaagaaaaa
     4501 attagggctt tagaaattgg aaaagttaat aactgtgaag aaaatgaaga ggaaagctat
     4561 gtcattaagt ctgatgtaga tgaaaattta atctatggag ataatgcaaa tgctatgatt
     4621 gaaaatatag ttgaattaaa tgcatcttct ggaacagttg cagttgttgg agatatattt
     4681 gatgttgaca ctaaagaact taaaaacgga aaaatactta tgatagcttc aattacagat
     4741 tatactagct caataagctg taaacttttt ttaacagata caaataagga tggagtactt
     4801 gaaaatgtta aaaaaggagc atacttaaaa atcaagggtg acatagttta tgatacatat
     4861 caaagagaaa ttagtatgat gattagtggg ataagaaaag aaactagaat agagagagaa
     4921 gataaatcag aggaaaaaag agtagaactc catgcacata cacaaatgtc ttctatggat
     4981 gctatttgtt ctgttaaaaa gcttgtagag cgtgcagcca aatggggtca ttctgctatt
     5041 gctataacag accatggtgt tgtacaagga tttccagatg ctatgaatgc aggtaagtca
     5101 aataatataa aaatacttta tggagtagaa gggtacctgg ttgaagatga ttctctcatt
     5161 atagaggatg caaatgataa agaactttcg cagacatttg ttgtatttga catagagaca
     5221 actggctttt ctaatacaaa tgataaaata actgagattg gtgctgtaaa aatagaaaac
     5281 tttaagattg tagatagatt tagtgagtta ataaatcctg aaaaagatat ttcttataag
     5341 atacaggaat tgacaggaat aactaatgaa ttaattaaag acaagccaac cattgaagaa
     5401 gttcttccta agtttatgga atttgttgga gatagtgtat tagtagcaca taatgcagag
     5461 tttgatactg gatttatatc gcaaaaatgt agggaacaag gcttgttata taataacaaa
     5521 aaagtagata cacttatgtt agcaagagta atgttgccaa acttaaaaag acatagatta
     5581 aatgtcgttg caaaagaact tggtattcct cttttaaatc accatagagc agtggatgat
     5641 gctgaagcta cagcacttat atttaataag tttttgcaga tgcttacaga aaaaggtgca
     5701 aaaactctaa gtgatgtaaa caatatactt ggaaagattg attacacaaa gcttagcaca
     5761 aatcatataa ccttgatagc aaaaaattct ataggtataa aaaatttata taaaataatt
     5821 tcagatgcac atgtaaatca tttttttaga gcaccaagaa tccttagaag tgtattaaat
     5881 gaatataaag aaggattaat aattggttcg gcttgtgaag ctggggtggt ttttcaagct
     5941 gtaaagaaaa acgtgtctga tgaggaaatg aaaaaaataa tagatttata cgattatatt
     6001 gaagtaatgc ctatagataa taatagattt atgattgata aaggagaagt aaaggacgaa
     6061 gaagagttaa gggagttgaa taggaaacta attgatacag ccaaaaaatt tgacaaaatt
     6121 ccagtagcta ctggggatgt tcatttttta gacaaacatg aagctgtctt aagaaaagtt
     6181 cttaaatatt ctcaaggttt taaagtagat gaagaagaaa cttatttaca ttttagaaca
     6241 acagatgaaa tgttggaaga gtttagttat cttggagaag aattggcata tgaagttgta
     6301 gttgaaaata gtaatctgat tgccgatatg gttgaagata taaaacctat accagatgat
     6361 acttatcctc caattataga gggctcagat gtggagttaa gagaaatgtg ttacaaaaaa
     6421 gccaaacgaa tctatggaga cccaatacca gaaatagttc aaaaaagact ggatagagaa
     6481 ttaaattcaa taataagcaa tgggtatgca gttatgtata ttatagctca aaaactggtt
     6541 gcaaaatctc tttcagatgg atatttagtt ggttcaagag gctcagttgg ctcatctttt
     6601 gcagctacta tgagtgatat aacagaagtt aatcctcttc cagcacatta tatttgtgaa
     6661 aacgaagact gtaaatattc attcttttat gaaataggtg aatggggctc aggtgttgat
     6721 ttgccagaca aggattgtcc aaagtgtgga agaaaacttg ctaaaaacgg tcatgatatt
     6781 ccatttgagg ttttcttagg ttttgaaggt gataaggaac cagatataga cttaaatttc
     6841 tcaggaaatt atcagccaac aattcataaa tacacagaag aactatttgg agaggggtat
     6901 gtatataggg ctgggactat aggtactgta gcagaaaaaa cagcttttgg atacgcaaga
     6961 aaatatgtgg aagaaaataa tataagtgta ccaaatgcag aagtacttag gctttcaaat
     7021 ggatgtactg gagtaaaaag aacctcagga caacatcctg gtggagttat ggttatacca
     7081 gactataaag atgtatacga ttttacacct atacagtatc cagcaaatga tacttcttgt
     7141 ggtgttataa ctactcactt tgattatcat tcaataagtg gtagaatact taaacttgat
     7201 atacttggac acgacggtcc taccattata aggatgcttg aagatatgac tggaataaat
     7261 ataacagaaa ttcctttaga tgataaagag actatgtctc tatttacatc tacagaagca
     7321 ttaggtgtta caccagaaga aataaactgt cctataggtt gccttgctgt accagagttt
     7381 ggaactaagt ttgtacgaca aatgttactt gacacaaaac ctactacatt tgcagaactt
     7441 gtacgtatat ctggtctctc tcatgggaca gatgtttggg taaataatgc acaagactta
     7501 gttagagaag atatagttgg attaaaagat gttatatcta cacgagatga cataatgaac
     7561 tatttaatat ttaaaggatt acctcccaaa atgagcttta caataatgga gagtgtaaga
     7621 aaaggtaaag gtttaaaacc agaacacatt gaagaaatga aaaaaaataa tgttccagaa
     7681 tggtatatag gctcatgtaa aaagattaag tacatgttcc caaaagcaca tgctgttgct
     7741 tatgtaatga catcatttag aattgcatat tgtaaagttc actatccaga agcattttat
     7801 gcgacttatt ttacgacaaa agttgaggat tttgatgcag atttaattgt taaaggatta
     7861 gatgctataa aatcaaaaat aaatgaaatt gagtcactgg gaaatgatgc aaccacaaaa
     7921 gaaaaaggta tgttgaccgt tttagaagtt gctcttgaaa tgtatgctag aggaataaaa
     7981 ttattaccag ttgatatata taaatcagat gcaactgagt ttatagttgt aggagaaaaa
     8041 acattacttc caccaatggc agcaatacaa ggtcttggag gaaatgcggc tataaacatc
     8101 caaaatgaaa gaaaaaatgg tgaatttata tcaaaagaag atttgagaaa gagaacaaaa
     8161 atatcaaaaa cggtaataga aactcttact aatcatggtt cacttgagaa tatgagtgag
     8221 agaaatcaat tgtcattgtt ttaagttagc ccaaaaagtt gcaaataaaa gaattttatg
     8281 atatcatagt atagaaaata gtatactttg cagaaactaa gagtgagaca gctgttctca
     8341 ctcttttatt ttaaatatat tattaaaaag ctggtttatt tttattaaat atattttatt
     8401 taagattata taaactggtc atttacaatt gaataggagg aactttaatg aaaaaaaatt
     8461 tagaagctac aattgaggag attgtaacta aaataacgga tgaacatgga tttgaaatgg
     8521 ttgatgttga atatgtaaaa gaagcaggag aatactactt aagagtatac atagataaag
     8581 aaaaaggaat atctttaaat gaatgtgaat tagttagtag agaattaagt ccaatactag
     8641 atgaaaaaga ccctataaaa gaaaattatt ttttagaggt atcttctcca gggcttgata
     8701 gagcattaaa aaaagacaga gattttgtta gatatcaagg tagagatgta gatttaaaat
     8761 tatataaacc attaaatgga tgtaagcaat ttgaaggtga acttgtagga ttaacagaag
     8821 ataataatat aaaaatcatt gcaaatggta aggaaatgga atttaataga aaagatgttg
     8881 ctattgtcag attagcaata aagttttagt ggtatattaa atagggagga tataaaaaat
     8941 gaatcatgaa tttatggaag cattagatga attagtagtt gacagaggta tagataaaga
     9001 aatacttata gatactatag aacaagctct tttaactgca tacaagaaaa actttggttc
     9061 agcacaaaat gttagagttg aatttgatag agacaaggga gatataaaag tattttctca
     9121 aagagttgtt gttgatgaat cagatttata tgatactttc ttagaaatag agttagcaga
     9181 tgctagagag ataaatccta attatgaatt aggtgatatt atagaacatg aagttacacc
     9241 taaaaacttt ggaagaattg cagctcaaac agcaaagcaa gtagttgttc aaagaataag
     9301 ggaagctgag agagaaatag tgtataatga atttatagaa aaagaaaatg aaatagttac
     9361 aggagaggtt gctagagcaa ataaaaatgt tgtttatgta aatcttggaa gaatagaagg
     9421 tataatgact caaagtgaac aaataccatt tgagaattat aaagcaggtc aaaaaataaa
     9481 attctatata cttgaagtta aaaagactaa caaaggacct caaatagttg tatcaagaag
     9541 tcatccgggt ctagtaaaga gattgtttga agaagaagtt cctgaaatat atgaaggaat
     9601 agttcaaata aaatctgtag caagagaagc agggtcaaga actaaaatgg cagtaagatc
     9661 tatagatgaa aaaatagacc caattggagc ttgtgttgga ccaaaaggac ttagagtaaa
     9721 aaatatagtg gatgaacttg gcgatgagaa aatagatata ataaaatata gtgaagaccc
     9781 agcagagttt atatcagcag cacttagccc atcaaaggtt gttagagtag atatagatga
     9841 agatgaaaag tctgccttag taatcgttcc agattatcag ttatcgcttg ctataggtaa
     9901 agaaggtcaa aatgcaagac tagcagcaaa attgactaac tggaaaatag atattaagag
     9961 cgaatctcaa gcagaacaag aaatgttaaa tcttgaaaat tccaaagaaa tagaagctga
    10021 ggatgttgaa gctgaattta tcgaccaaga agagttagat acttcagagg ataattttag
    10081 tgaagaagag taaggaggga tgattttgaa aaaagtaaaa aaagtgcctc aaagaaaatg
    10141 catagcatgt caagatagag actctaaaaa agagcttata agaatagtta aaaataaaga
    10201 aggaaaaata tttttagacc caacaggaag agccaatgga agaggagcat atgtatgtaa
    10261 aagctctgaa tgtctaaaaa aagctataaa gagtaaagca ttaaataaag cttttaaaat
    10321 agatgttcct gatgaagtct atgataatct acttatggag ttagaagaat atgaaaaata
    10381 ataaagaaaa agtactttcg ttcttagggc tcgcaactcg tgcagggaaa atagtgtctg
    10441 gtgatgattc aactttgctt gaccttaaaa aaggaaaagt aaatttgatt ttaatcgcag
    10501 aagatgcatc aaataatact aaaaaacttt ttaaagataa atcaactttt agaaatattc
    10561 catatctatt tttttcaaca aaagaggaaa taggatttgc aataggaaaa tctccaagag
    10621 cagttgtagg aataaaagat gaaaattttt ctaaaaagat aattgaacta atagaaattt
    10681 aaaataaaat agggggtgat cttgtgtcaa aaacaagagt ataccaaata gcagaagaat
    10741 taaatatatc aaatgaagag cttataaata agttagctga attagatata aatgtaactg
    10801 acaaagattc agtattagaa ggtgaagagt tagaattagc acttgaaatg ttaggtgaag
    10861 atttatctca agaaaatgga aatgttatag aaatagatgg aaagttgaca gtacaagtat
    10921 tagcaacgaa attagataaa tctccatcag aaataattat gaagcttatg aaaatgggaa
    10981 ctatggcaac aataaatcaa gagataagtt ttgagattgc tgctttggct gccaaagact
    11041 atggatttga attaacagta gctgaaagtg atgatacaga agctttagaa atagaagctt
    11101 taatggaaat tgaagaagac aaagaagagg atttaaaacc tagaccacca gttgttacag
    11161 ttatgggaca tgttgaccat ggtaagacat ctttactaga tgcaataaga aaaactgatg
    11221 tgatctcagg tgaagctgga ggaataactc agcatatagg tgcttcagaa gttaaaatca
    11281 atggacacaa aatagtattt ttagatactc caggacatga ggctttcaca tcaatgagag
    11341 caagaggagc acaagttaca gatatagcaa tattagtagt tgcagcagat gatggtataa
    11401 tgcctcaaac agttgaagct ataaaccatg ctaaagcagc aggtgtacct ttaatagttg
    11461 ctattaataa aatagataaa ccaggtgcaa acccagataa ggttaaacag gaattagcag
    11521 accaaggatt attagttgaa gactggggtg gagaagtaat agcagttcca gtatcagcta
    11581 agaaaaaaga aggaatagat acacttttag aaatggtatt attggttgct gaaatggaag
    11641 agttaagagc taatccaaat aaaagagcag taggaactgt tatagaagct gagcttgata
    11701 aaggaagagg gccagttgca acagtacttg ttcaaggtgg tactttaaca gtaggtgacc
    11761 caatcgttgc aggtgttgca tgtggtaaag ttagagcaat gataaatgca aaaggtaaga
    11821 gagtaaaaac agcaggacca tctacagcag tcgagatatt aggtctatca gaagttccac
    11881 aaggaggaga ccaatttgtc gaagttccaa ctgataagat tgctagaagt gtagcagcaa
    11941 gaagacaaca aatagttaga gatgaaatgt taaaatcaac tcaaagatta tcactagatg
    12001 ctctatttag tcaaatgagt gaaggttcta taaaagacct taatatagtt ataaaagcag
    12061 atgtacaagg ttcagtacag gcagttaaac aatctttaga aaaattatca aatgaagaag
    12121 ttcaagttaa agtaatacat ggtggtgttg gagctgtaac agaatcagac atattacttg
    12181 cagcagcttc taacgcaata ataataggat tcaatgtaag accagttcca ggtgcagaat
    12241 ctctaggaga aaaagaaaat gttgatataa gaacatatac tataatatac aaggcaatag
    12301 aagatataca agcggctatg actggtatgt tagaccctga atatgttgat gaagaaacag
    12361 gaaaagctga aataagagaa atatataaaa tatctggtgt tggaacagta gctggatgtt
    12421 atgtgactaa tggtaagata tttagaaatt gtaaagtaag attagttaga gatagcataa
    12481 taatacatga aggtgagctt gcagcactta agagatttaa agatgatgta aaagaagtta
    12541 attctggata cgaatgtggt atgagttttg taaattataa cgacataaaa gaaggcgata
    12601 tagtagaagc ttatataact aaagaagtag aaagaaaatt ataaattcgt atcaaagaaa
    12661 atcagttagt aaagaaggtc gatggtatgg catcatataa tagaacaaga aggatagcag
    12721 aagaaataag aaaagtcgta agtactatgc ttataaatgg agtaaaagac cctagaataa
    12781 catctatggt gagtgtaact gatgtagaag ttacaaatga cctaagatat gcttatgtat
    12841 atgtaagtat tctaggcgga gatgaagaat ccacactaac aggtcttaaa agtgctggag
    12901 gatatataag aagagaagta ggaaaaaata taaaacttag atatattcct gagatagtat
    12961 ttaaacttga tgattcaata gaaaaaggaa tgtatatgga tagccttata aaaagagtta
    13021 atgaaaaaaa tgctcaacaa aatgaggatg aaaattatga tgaataatat ggatagtatt
    13081 ataaactata tttatgaggg tgactatttt atagttacct ctcatatcag tccagatgga
    13141 gacaatattg gttctacact ttcaatgtat tatacattga agaatttagg aaaaaatgta
    13201 tattatgtac ttgatgatga agctccatta aatttaaggt ttttggttga aggtgtaaaa
    13261 atctataagt ctaatgaatt taatatgaag aactattctc taattgcact tgattgtggg
    13321 gataagatga gaatatgtgt gagtgatgaa atcaaaaata atgcatcaaa attaatctgt
    13381 attgaccatc atgctagtaa tgattcatat ggagatttaa attatgtaga tattgatgca
    13441 tcttctacat gtgaattagt ttataattta ttagttagat ttcagcaaat aaaagatatt
    13501 aatattataa atgaagatat agcaacatgt ttatatacag gtcttgtaac tgatactgga
    13561 aacttttcgt attcaaatgt acatgcaagt agctttgaaa tggcaaaaaa tttacttgtt
    13621 ttaggtgcac aaaaaaatac tataatacaa aatatatatc aaagcaattc ttctggttat
    13681 tacaaattat taggagaagc tctaaagggt ttggagatat ttgattaaaa aatagttacg
    13741 cacactcgtg actttagtca tgagttagta gctaaaatag tcagcatata gggaaactta
    13801 tatgtagaga taggataaaa cctatccaat actacttgaa ttgctggaaa cccctaaagc
    13861 taaccaaact aaaacataag gatgaaataa acctaagtgt gaaagttacg aaagtagaaa
    13921 aaattggtta gatggtataa ggttaaaccc taagtacttt aaaatgggca atcagcaggt
    13981 aa
//
LOCUS       DAEQAF010000093        13898 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.096, whole genome shotgun sequence.
ACCESSION   DAEQAF010000093 DAEQAF010000000
VERSION     DAEQAF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13898
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.096"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            154..1659
                     /locus_tag="KRN00_002957"
     CDS             154..1659
                     /locus_tag="KRN00_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBH1828812.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            2049..3146
                     /gene="dinB"
                     /locus_tag="KRN00_002958"
     CDS             2049..3146
                     /gene="dinB"
                     /locus_tag="KRN00_002958"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBH1828813.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            3409..4545
                     /locus_tag="KRN00_002959"
     CDS             3409..4545
                     /locus_tag="KRN00_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828814.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            4538..6085
                     /locus_tag="KRN00_002960"
     CDS             4538..6085
                     /locus_tag="KRN00_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBH1828815.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVVVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMRHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILDDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            6419..7285
                     /locus_tag="KRN00_002961"
     CDS             6419..7285
                     /locus_tag="KRN00_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBH1828816.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            7426..8568
                     /locus_tag="KRN00_002962"
     CDS             7426..8568
                     /locus_tag="KRN00_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1828817.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            8952..10190
                     /locus_tag="KRN00_002963"
     CDS             8952..10190
                     /locus_tag="KRN00_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828818.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIKMQRLTLILLTMIMIFSFPQLFMTLNV
                     ERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLFGITISNIYLYFFNMIFEFKLKI
                     GKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQYDTKFISGEPILEKIAMIIERLL
                     YSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCFCVLSVIENSEKRVPKLCMGIII
                     FNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTKALRKNEKNMYNIFLSLLLVTIV
                     ISNVNGFIEILNIGIKSYPV"
     gene            10219..11106
                     /locus_tag="KRN00_002964"
     CDS             10219..11106
                     /locus_tag="KRN00_002964"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBH1828819.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            11140..11769
                     /locus_tag="KRN00_002965"
     CDS             11140..11769
                     /locus_tag="KRN00_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBH1828820.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKLKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            11774..12238
                     /locus_tag="KRN00_002966"
     CDS             11774..12238
                     /locus_tag="KRN00_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBH1828821.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            12488..13855
                     /locus_tag="KRN00_002967"
     CDS             12488..13855
                     /locus_tag="KRN00_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBH1828822.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
BASE COUNT         5261 a         1466 c         2380 g         4791 t
ORIGIN      
        1 taccataaaa ctatcttgaa aaaaattaat cttaattgta taatattact ttgagtgaaa
       61 aagtattaac atttttttat aagatgtttt actaaaaaaa tatatataaa tatactgtta
      121 tcaacaagaa atttaattta gtgaggtgtt aagatgaaag taggatttga ccacaaaaaa
      181 tatttagaag agcagtctaa atatatctta gaaagagtaa ataattttga caaactttat
      241 ttagagtttg gaggaaaatt gatgggagac cttcatgcaa aaagagtact tccaggattt
      301 gatgaaaatg caaagataaa agtattacaa catatgaaag aaaaagttga agttgtaatt
      361 tgtgtctatg caggagatat agaaagaaac aaaataagag gagactttgg tatcacttat
      421 gatatggaag ttttaagatt aatagatgat ttaagaggtt atgaactaga tgtaaatagt
      481 gtagtgatta ctagatttga aggacaacct gctacaactg tatttataaa taaattagaa
      541 cgtagaggaa ttaaagttta taagcattat ccaacaaagg gatatccgtc agatgttgag
      601 actatagtta gtgatgaggg atatggagca aatgaatata tagaaactac aaagccaata
      661 gtagtagtca cagcaccagg acctaatagt ggaaaacttg gtacttgtct aagtcagttg
      721 tatcatgaaa ataaaagagg taatgtagtt ggatattcta agtttgagac attcccagtt
      781 tggaatgtac ctgtaaaaca tcctttgaat atagcttatg aagcagctac agttgattta
      841 aaagatgtga atatgataga ttcattccac cttgaaacgt atggtgaaat gtcagtaaac
      901 tacaatagag atttggaatt atttccagtg cttaaaaaaa taatagaaaa gataactgga
      961 aaagaatcaa ttttccaatc tccaactgat atgggtgtta atagagttgg ctttggaata
     1021 atagatgatg aagtaataag aaaagcttct atagaagaaa taataagaag atattttaaa
     1081 actgcctgtg agtataaaaa gggacaagtt gataaaggtg cttatgatag aatgaaaatg
     1141 attatggaag agcttaactt aaagccagaa gatagaaatg ttgtattacc tgctagaaac
     1201 tacagtaata aattgaaaga aagtgctgac aagaatgata cttgtcctgt agttgcatta
     1261 gaattagaag atggtacaat attaactggt aagggttctg atttaatgaa tggaactgca
     1321 gcagtagtat taaatgctat taaacattta gccaatatat ctgatgatat gcacttaata
     1381 tcacctgtaa tattagaacc tatcataaac ttaaaaacaa agactttagc tagtagaaat
     1441 gtttcactta gttgccaaga ggtgttaact gcacttagta tttgtgctgt aactaatcca
     1501 actgcacaat ttgctatgga aaagttagca ttattaaaag ggtgtcaagc tcattctact
     1561 actatattaa atagagatga tgaacaaaca tttagaaaac ttggtataga tgtaacttgt
     1621 gacccagaat atccttcaca aaatctttac tatagttaaa attatataaa aaaatatggg
     1681 ctgttttaaa gtaatagttt gagcagtcca ttacaattat aataaaatca gtaggctgtc
     1741 ttgtataaga cagtcttttg tttttaaaac atcccataaa ttaaatatat atactgttat
     1801 ccataaggaa ttttaaattt agttccttgg aatacctatt gtaaagcttt tatatagttt
     1861 ttgcaagtgt ttttaaggat tttttataaa ttatattgaa gttaatggat tatagatggt
     1921 tttatttatg gaaaatatga atatataaag aaaataatga aaaaatacca aaaagaaaca
     1981 taagtttggt ataattaaaa agtaatataa ataaaattaa tctatttata ctttaaaagg
     2041 tgataataat gaaacattat agaaaaataa ttcatataga tatggacgct ttttatgcat
     2101 ctatagaaca aagagataat aaaaaattaa aaggaagacc tgttattgtc ggtggaaatc
     2161 cacaaagccg aggtgtggtt gcaacctgtt cttatgaagc tagaaaattt ggtatccatt
     2221 cagctatgcc atcagctgta gcttacaata ggtgtccata tgcagttttt gtaagaccta
     2281 gatttgatgt ttataagagt gtgtcagagc aaataagaga tatattttat agatacacag
     2341 atttagttga accattatct ttagatgaag cttacttaga tgtaacaaaa aataaaaaaa
     2401 atattgattc atcaattgag atagcaaagc aaataaaaaa agatatattt agagaagttg
     2461 gtcttacttc ttcagctggt gtgtcataca ataagtttct tgctaagatt gcatcagact
     2521 taagaaagcc aaatgggtta actgtaataa ccgaagaaaa tgcccaggac tttttagata
     2581 aattacctgt gaataaattt tttggtgttg gaaaagttac ttcaaatact cttaaaaatt
     2641 taggtataaa aactggatat gatttaaggt gtttaaattt atttgaactt gaaaatatat
     2701 tcaaaaaaag aggttatgaa ttatataaat ttgctagagg aatagacgat agaccagtgg
     2761 aaccaaatag ggttagaaaa tctgttgggg ctgagactac attaagtcat aatttggata
     2821 ttgatgaaga agaaacacgc aacattcttg atgaactttg tgaagaagta tgtcatagat
     2881 taaaaaactc tgagaagttt ggaaaaacat taacattaaa aattaaatat gaggacttta
     2941 caaagataac tagaagcctt agtttagaac actatattga cgaatataat gatataagaa
     3001 gtggtgtaga taatttgttg agaaatgttg aggttaatgg aaaacaaatt aggctattgg
     3061 gagttacaat atcaaaccta agtgataaaa aagaaactta taaagatatt acattatttg
     3121 aatacatgga tagtatccaa atgtgagttt tgtttaaatg aaataacact agctttaata
     3181 ctatataatt gaggctagtg ttattttatg aatattttta tattttttgt tttttgacat
     3241 tgtatattat atactatata taaatacttt atatttgtag caatattcag acaaatagtg
     3301 acctaaaaat cgtactttgt ttacataaat aaaatagtat gatataatta taaaaacaac
     3361 ttataatatt ggagaaggtt gcttgttcga aaaaggggat gataaattat gatagagata
     3421 agaaatgtaa caaaaaaaat aggaaataat gttatattag atgatatttc tctagttgta
     3481 gaaacaggta cattggtagt tttgattggt tcaagtggtt gtggaaagac tactactttg
     3541 aagcttataa acaaattaat aaaacctaca tctggtgaga tatatattaa tggcaaacca
     3601 atttctcagg aaaatgaaat agagcttaga agaaaaatag gatatgttat acagaacaca
     3661 ggcctattcc ctcatcttac aataaaagaa aatatagagc taattccacg cctaaaaaag
     3721 gaaaaatccg ttgaagaaat tgaaaaaaga acgttgcaac tacttgagat ggtaggactt
     3781 gatagtgatg aatttttgaa taagtatcct tcagaactta gtggtggaca gcaacaaaga
     3841 atcggtgttg caagagccat tgctactgat gctgaaataa tattgatgga tgagcctttt
     3901 agtgctttag acccaataac gagaacatct ttacaagaac aattattttc tcttcaagat
     3961 gaattgaaaa aaactataat atttgtaact catgatatgg atgaggcttt aaagatagct
     4021 gataaaattt gtattatgaa ggatggaaga atagcacaat atgatactcc cgaaaatata
     4081 cttagaaagc ctgcaaatga ctttgtaaaa gattttatcg gagaagatag agtttgggat
     4141 aatccagaat atataaaagc aagagatatt atgataaaaa atcctattgc tgttaattct
     4201 actagaactg taactcaagg aatagaaatt atgagaacga gtaaggttga tagcttacta
     4261 attatagata gagcaaaaac attaaaaggt attgttactg taaaagatat gaaagatatt
     4321 gatgataagt caatattact tgctgatatt atgtcaagtg agcctttgca tgtaaatgaa
     4381 ggtgataatt tagtagaaat actaaatgta atgaatcgta attcggttgg atatattccg
     4441 gttatttctg atgaaaataa actggtaggg cttattacta gaagtagttt actttctgtt
     4501 ttaagtgaac aattcttaga aatggaggtg agtgttcttg gctaattttt ttaactttat
     4561 actattacaa aaagataaga ttatagagct tttaatacaa catatgagtc taactgttac
     4621 atctatttta atagctataa tagttggtgt tcctcttgga ataattattt caagaatctc
     4681 atctcttaga aagtttgtac ttggatttgt aaacttagtc caagcagttc cgtctatggc
     4741 acttttgggt cttcttgtac ctatacttgg tataggaagt aaaccagcca tatttatggt
     4801 agtggtttat tcattactac caattgtaaa aaatacgtat ataggtataa caagtattga
     4861 cccagtagta ttagaatcag ctaaaggtat tggtcttaca agaaatcaga cattatttaa
     4921 aatacaattc cctttagcac ttcctataat aatgggtgga gttagaatat ctgcagttac
     4981 agctgttggt ttgatgactc ttgcagcatt tataggtgct ggtggtttag gatatttagt
     5041 attttcaggg gttcaaactg taaataataa tatgatttta gcaggggcaa tcccatcatg
     5101 tataattgca ctgttagttg attatttatt tagtaaaatt gaagttgcag ttactccaaa
     5161 aggattaaat ccaaaagcac ctaagaagaa ttatatagca cttaaagtaa tatctgtagt
     5221 ggttgttgtt tcaatgttgt tcgttgtttt tagttctagt ttttcaagta aaaaagatac
     5281 aataactatt ggttctaaag attatacaga acaacttata cttggcaatg tttatgctga
     5341 attagtagaa aaaaatacga atcttaaagt taagaagaat ttaaatctag gtggttcatc
     5401 tgttgcattt aatgcaatta aatctggtga gttagacatg tatgttgact atacaggtac
     5461 acttttggta aatgtaatga gacatgcacc gattaaagat gctgatgaag catataatgt
     5521 tgtaaaagat actatggaaa aagaaaatca gttaacttta cttgaccctc ttggatttaa
     5581 taatacttac acattagcca tgatgcctga aactgctgaa aagtatggaa taaatactat
     5641 ttctgatttg actaaatatg gtaaagaatt tacattctca ccaactttgg agtttgaaaa
     5701 tagagaagat ggtcttgtag gactttctag agattatggt ttaaaattca aagatgtaaa
     5761 agcaatgaat ggaagtttaa gatatacagc tttagataat aatgaatctc aggttataga
     5821 tgcattttta actgatggtc ttattaaaaa gtttaatctt aagatattag atgatgataa
     5881 aaatttcttt gtaccatatt atgcagcacc attagtaaga gaagatactt tgaagaaata
     5941 tcctgagtta gaaaaagtta tgaatatgct ttcaggaaaa ataaatgaag aaactatgag
     6001 agaacttaac tatcaagtgg atgaacttgg taaatcacca gaagaagttg ctcattcatt
     6061 cttagttaaa gaaggcttag tataaaaaat taatagttta tatcaaaaat ttaagggagt
     6121 gtctcaaaat gaacttttta gttcatgagg cactcttttt tatatgaaat caaatatatt
     6181 ttatcatttc aacaataaaa aagaagatta tctttatttt gagacagtct cttattttta
     6241 tgtataccaa aaccatacct acgattttta tttataatta agtttcaaat agaatgaaca
     6301 agtacaacca attttgaata taaatatagt aaatgtgctt atatacgatt ttattgtctg
     6361 gttgattgat attgatagat agctttcttt attgaatcga agggaggggg aatttgttat
     6421 ggataactat aagaaagtga agcaagtatt gtggataatt ttatttgcta attttgcagt
     6481 agcattatta aaaatcatta ttggtaatca aataaaaagc tatagtatga cagcagacgg
     6541 atttcattct ttgtcagatg gagcatctaa tatagtgggg cttataggta ttttctttgc
     6601 atctaaacca aaagataaaa atcatcctta tggacataaa aagtttgaaa ttataaccag
     6661 tttatttata agtggtatgt tgtttgttat agcaattaag ataattctta gtgcagtgtt
     6721 aagaatagct aatccagttg tacctgctat aactatagaa agtttaattg ctttaattat
     6781 tacacttttt ataaatattt ttgtatgcat gtatgaatat agaattggga ctaaactaaa
     6841 tagttatgtt ttgatttcgg attcattgca tacaagaagt gatatatttg tgtctctagg
     6901 tgtattggtt actttagttg gtgttaagtt aggatttcca gtaataatag aatctatagt
     6961 tcctattatt atttctgcat tcataattta ttcggcttat ggaatattta ggccatctat
     7021 tggaattttg gtcgatagag tggctgtaga tgaggattat ataaaagaaa ttgtgtttga
     7081 atttaatgag gtaagggatg ttcacaatat cagaagtaga ggtagcaaaa gttctattta
     7141 tattgacatg catgtaatgg tagacccatt tataagcgta gagcaatctc atgatttaac
     7201 acataaaatt gagaaacaaa tacaagaaga aattaatgaa aatgctcaag taatagtcca
     7261 tattgaacct ttttatagtt tttaacttag ttataaaata caagttataa aaaaatataa
     7321 tttataaaaa aaatattata ccataaataa tttataaaaa ttatttatgg tataatattt
     7381 tctataaaga aattaagtct taatatatct aaggaggaat ttacaatgag atacgttgaa
     7441 tatggaaaga cagggaaaat ggtttcagta gttggctatg gaggattaag gtttgattta
     7501 gaaaaaagta atcaagaaaa tgctgattta gtcaaatatg cgtatgaaaa aggtattaat
     7561 tactttgata cagcaccagg gtattgtgat gacagaagtg aagatatatt tggactagcc
     7621 tttagacaaa tgataaagga aggtaagacc gatttttatg tatcaactaa agaaaagcca
     7681 aaagcatgtg atacatcaga aaaagctata gaggctgtaa aaaaatcaat agaacgatta
     7741 ggcgtatcta aaataaattt ttatcatgtt tggaatatta gaaagatgga acattacgaa
     7801 ctagcaatga gacctggagg tcaatatgaa ggattattga aatgtaaaga agaaggattg
     7861 atagaccata tagtattttc atctcatcaa ccaggagatg aggttataga tattctaagt
     7921 gaaaataagt ttgaaggtgt aactatggga ataaatatat taaactttcc atataggcta
     7981 aaaggtgcca aatatgctgt tgataatgga tatggtgttg tggcaatgaa tccattaagt
     8041 ggtggaacta ttccaaaata taataaagaa ctttcttttc tatcaaaaga tggcgaaagt
     8101 actatagaat cagctttaag attcaacata ggaatttcac aaataagtat atctttgata
     8161 gggtttaata aaaaacaaga tatagatgat gcatgtaaaa ttgcagacga aaatagaatt
     8221 tattcagatg aggatataca tgatattgag actagattaa ataagaatat gaacgaaata
     8281 tgtacaggtt gtggttattg taaagtatgt ccaaaaggta ttaatacccc agcctatatg
     8341 cttttttata atgaaaagca gatgtttaaa aagagtgatg aagaaatgac aaagttagtt
     8401 tatggcttag gacattggaa ttacacaatg aatagtaagg caaaagctaa agaatgtata
     8461 tcttgtggaa aatgtgaagt tgaatgtact cagcatttac ctataataga tagattaaaa
     8521 gaaattaaaa aatgggaaga agatggagct aatagtgtta aagtctaatt aattttatac
     8581 tatatttgaa atttgtatag tatttagtaa tgttttaaaa tatagtttta atatttaagg
     8641 agacagatta taattttgtc tccttaaatt atgctttaat ttgttatagt ttaattccat
     8701 aagcaacatt gtatattttt atataaagtt tttcaaatat tttacattaa tattgcttac
     8761 aaattctcat tttatacaac actaatctat gttatataaa caatacttga ctgattataa
     8821 catcaataaa gtaaatattg tggttgtaaa taaagagtta ttcaattaca ataaaacaag
     8881 taagaacatt atgaagatgg ctattaaata taaggaataa attgtaggtg tcagcaaatc
     8941 ctatataatg aatggatggt gatatattga tgagtaaaat attaaaatat aaaaacgaga
     9001 tgtttttgtt tatattagtt gtaataactt acttaataat aactaagata tttttttcta
     9061 agactactat attttatgat ttaaacaata cttatgatgt attgttagat acagatacag
     9121 gagttttatt caatttaaat gtatttgcta taagtcaaga caatagtaag cacatattgt
     9181 tttcagcaat tatatcaatt tttgcatatc caatatacct attttgtact tcaatagcaa
     9241 atcctgggac aacagatttt aatagtgcct atgggtttgg actaatttgt ctacaaataa
     9301 taactagtgc tatgtcaata actttagtct ttaatcatat taaaaagata aaaatgcaga
     9361 gattaacttt aattttactt actatgataa tgatattttc ttttccacag ttatttatga
     9421 ctttaaatgt agagagattt atatatagcc aattttcatt aatatttttc atagttattg
     9481 caaataagat gaaaggaaaa aattcttatt tagtagaatt agcagctatt cctctatttg
     9541 gaataactat tagtaatata tatttgtatt tttttaatat gatatttgag tttaaattaa
     9601 aaataggaaa aatgttaaaa catttaatta catttatcct aatggcatat atttgtgtag
     9661 tttcaacgaa gtcttatgag agttttatga accttggaaa tgtaatacag tatgatacga
     9721 aatttataag tggagaacca attttggaaa agattgcaat gattatagag agattattgt
     9781 attcggtttt ttattttcct ggagcaagta ttaaaaaagg gttatttttg caaaatggag
     9841 aagttgctac aataccagta attcttacat tattagcttt atgtttttgt gttttatcag
     9901 ttattgaaaa ttcagaaaaa agagttccta agctatgtat gggaataatt atattcaatc
     9961 taactttaca tggtatagta ggatataatc tagtcaattc aagtattatg gctataaatt
    10021 ttagttttgc agttataatt ttattggctt actttacgaa agcgcttaga aaaaatgaaa
    10081 agaatatgta taatatattt ctatcgctgt tattggtcac tatagtaatc agtaatgtca
    10141 atggatttat agaaatttta aacataggga taaaatcata tcctgtttaa aaaataatat
    10201 tgaaagggta gtaagtttat gaaacagacc aatacaagta taaggcttct tactaaaatt
    10261 tcagattata taaagttaat gagaataaag caatatataa agaatttctt tgtattttca
    10321 gctataattt tttcaaacaa catactaaat ataaatttat ttttaaatac gtttattgcg
    10381 tttgtgtgtt tttgcctaat gtcatcatca gtatatgcac tgaatgatgc tatagacatg
    10441 gataaagata aaaaacatcc taaaaaatgt aatagaccag tggcaagtgg aagaataagc
    10501 aaaaaaagtg ctaatatact atttgtagta ttagctttaa tttcagtctg tttatcaaca
    10561 gttgttagtt ttaatctttc tataattctt agtctctatt tgataaacaa tatattatat
    10621 tctcttaaac taaagaatat aatactatta gatgtgtttt caatatctct tggttttata
    10681 cttagggttt atgcaggatg tgtagccata agtgttagtt tatcaaattg gataatttta
    10741 tgtacatttt tcttatctct gtacttagct cttggaaaac gtaaaaaaga aatagaaact
    10801 ctaagagatg atgcagttga acatagaaaa atattggaag attatgacat agaaaatcta
    10861 aatcaaatga tgatagttat attaagttct acaattgtat gttatgcatt gtattctaca
    10921 agtaatccag aaaagccaca tatgatattt acaacaatat ttgtagttta tggtgtactt
    10981 agatataatt atataattaa cactacaaat gaaaataatc ctactgatat tgtcctaaaa
    11041 gataatgctt taaaaataaa cgtaatctta tggataatta catgtttaat aatattgatt
    11101 ttttagtgat atttttagtg ataggatggg gaaatactta tgaaaaaaag tgtattatta
    11161 cttgatgtag attatactgt tataaatact gatagcatga tagatttttt tatttactct
    11221 ttaaaaaata aaacctttaa aactattata aagttaccat acattatttt tattctattt
    11281 atgtatttaa ttagaatgat acctttgaag aaggcaaaag aggcaatctt ttatccaata
    11341 gtagatttta gtgaagaaga tttaaaaaag ttttttgatg attgcataat gaaaaaaatt
    11401 aacgaatcta tgaaaaaggt tatttacaaa aataaagaag aagataatgt tataattatg
    11461 ataactgcat ctccatatgc atatatgaaa tattttaagt attatggtct tgcagacgag
    11521 gttataggca cggagttttt ttatgaaaat tcaagatata aaaatcaatt cattggagaa
    11581 aactgtaagg gaattgaaaa attaaaaaga ataaaggctg tattaggtaa acttgggata
    11641 gagattgatt atgaaaattc atatgcatat tcagactcta agagtgattt accaatgctt
    11701 tcattgacta aaaatgcatt tttagttagt aaaaaggatg gtgaggttat agaacaaata
    11761 aattcataac ttaatgtcac ttagaatagg agggaatagt ttgggatatt tacacatatt
    11821 aattttatct atggttcctg taacagaatt gaggggagcc attcctatag gtattgcaat
    11881 gggcttaaat cctatatggg tttatgtatt tagtgtaata ggttctacat tggtatcgat
    11941 tcccttgata ttgacattca gacatgtatt acaattttta agagggaaga aactatttaa
    12001 agggattgct gatgtaattg atagaaaaat aaactcaaga atgaagaaat taaaaagtgt
    12061 ttcgataatt ggtataatac tatttgtagg tataccactg ccaactacag gaacatggac
    12121 tgcatctgct atagcttcca tattaaaaat gagaataaaa gatgctttta tgggagtatt
    12181 tcttggcaat ttgttatcag gggttatagt ttcagctctt tctttacata taatataaaa
    12241 ctatctaagt aatatacttg gatagttttt ttatgagtat gtgtgaaaaa tttttaataa
    12301 taaataaaaa atgagataaa gtatttaact tcagttagtt ctaaaatgtt tactatggca
    12361 aaagaaatat agtatagtat tacttgtagg gaaagtactc taaatttgtc tgctaataaa
    12421 atgaaatttt tatatagaat aaaattttag tgatacattt taattattgg attgaggagg
    12481 ttttaaaatg gaaaattcaa acactaactt aggtagtgaa agtgtgggta aattattatt
    12541 taaacttgct acacctgcta ttatcgcaca aattgtaaat gttttataca acatagtcga
    12601 taggattttt attggtagaa tggaaaatgg agaagttgct atggctggtg ttggagtggc
    12661 atttccaata ataattataa taactgcatg tagttattta atcggtatgg gaggaggtcc
    12721 attagctgct ataaaaatgg gtgagcaaaa caatgatgag gcagagaaaa taatgagtaa
    12781 cagtttttct gtactggtga ttttagcaat acttttgact ataggtttta agattggaaa
    12841 agagccttta ctttggatgt ttggagcaag tgaatctaca attggatatt caatggacta
    12901 tttaaatatt tatttaatag gtacagtgtt tgttcagatt tcaatgggta tgaatacttt
    12961 tataaatacc caagggtttg ctacaactgg aatgatgaca gttgctatag gtgctttaat
    13021 aaacataata cttgacccga tttttatatt tggctttaat atgggtgtaa aaggagctgc
    13081 attagctact ataattgcac aaggcgtttc tgctatttgg gtacttatgt ttctctttgg
    13141 aaagaaaagt atacttaaaa taaaaaagaa gtatatgata ccaaaagcaa gtatcatctt
    13201 accagtgctt ggcttgggaa tctctccatt tataatgcaa tctacagaaa gtttagtact
    13261 tatagcctta aatagtaaat tacaaatgta tggaggagat ttagcagtag gttcaatggc
    13321 tataatgagc agtataatgc aaattcttat gcttcctaat atgggggtta cacaaggagc
    13381 acaaccaata ataagttata attatggttc aggtcaactt gatagagtaa aaaagacatt
    13441 taagttgtgt ttgttgtcat gttttacata ttctactatt ttatggcttt tattaatgat
    13501 atttcctgca ttttttgtta gtatatttaa taagaatccg cagttactta gtatgactag
    13561 ttggagtata aaaatatatt ttgctggtgc ttttatgttt gggattcaaa tagcttgtca
    13621 acagacattt ttagcacttg gaaaagcaac aatatctttg gttttagctc tacttagaaa
    13681 gattgtactt ttaatacctt taatatttat actcccaaca ttctttaatg aaaaactttt
    13741 tgcagtaatt ttagcagagc cagttgcaga tataacagct gctactataa cagcaatttc
    13801 tttctttata ttttataaat gttttctatc aaaacctaaa gcaataaaag aataagatat
    13861 acaatataaa ttttttatga aaatatttta ttagataa
//
LOCUS       DAEQAF010000094        13876 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.097, whole genome shotgun sequence.
ACCESSION   DAEQAF010000094 DAEQAF010000000
VERSION     DAEQAF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13876
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.097"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            389..1039
                     /locus_tag="KRN00_002968"
     CDS             389..1039
                     /locus_tag="KRN00_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBH1828823.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLVQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            1241..1912
                     /locus_tag="KRN00_002969"
     CDS             1241..1912
                     /locus_tag="KRN00_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828824.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHYIVTLIRSGYK
                     FEVKE"
     gene            1909..3039
                     /locus_tag="KRN00_002970"
     CDS             1909..3039
                     /locus_tag="KRN00_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828825.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKLEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            3459..4304
                     /locus_tag="KRN00_002971"
     CDS             3459..4304
                     /locus_tag="KRN00_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828826.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSLFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFAYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            4304..5332
                     /locus_tag="KRN00_002972"
     CDS             4304..5332
                     /locus_tag="KRN00_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828827.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            5335..6348
                     /locus_tag="KRN00_002973"
     CDS             5335..6348
                     /locus_tag="KRN00_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828828.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKDSILKEFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(6865..8115)
                     /gene="cme"
                     /locus_tag="KRN00_002974"
     CDS             complement(6865..8115)
                     /gene="cme"
                     /locus_tag="KRN00_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBH1828829.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(8201..8947)
                     /locus_tag="KRN00_002975"
     CDS             complement(8201..8947)
                     /locus_tag="KRN00_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1828830.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(9081..10103)
                     /locus_tag="KRN00_002976"
     CDS             complement(9081..10103)
                     /locus_tag="KRN00_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBH1828831.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKVVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKIIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(10103..12523)
                     /locus_tag="KRN00_002977"
     CDS             complement(10103..12523)
                     /locus_tag="KRN00_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBH1828832.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPVSDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSDKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLGAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQTNSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVHFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPTLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKTLKENP
                     KSITGRYL"
     gene            complement(12609..13529)
                     /locus_tag="KRN00_002978"
     CDS             complement(12609..13529)
                     /locus_tag="KRN00_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1828833.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
BASE COUNT         4883 a         1806 c         2188 g         4999 t
ORIGIN      
        1 gttttctata ctataattat ttaaaactaa atataaatgt tggaattatt taggacttga
       61 aattgtctaa aaataaatat aagtgatgaa gaggtgatgt gatgagatta gatatggata
      121 gtatgttata tgtactaatt tatatgacat tattggtatc tatcattgga agtatatttt
      181 atttttgtaa agacctctta aatcataaaa ttaagtatgt tttaataaga gacatatttg
      241 taaatagaat tacatattct gaagaacggt tgcctaaaca gtatatagtt tttcagaaat
      301 atgatatttg gaggtattgt agtttgtttt aatttgaaat gaatctatta taaattctaa
      361 agtttaaaaa taaaaaggag agaataaaat ggatttcatt tcaagtatat tgcaaggatt
      421 attaagtata ttatttaatt ttacaggtga ttttggaatt tctattgtac ttataacttt
      481 aatcgttaaa ttagtactta tgccactatc attaaaacaa agattttctg taaaaaaaca
      541 gcaagaatta gctgaaaaaa tggaacatat aaaagaaaag tataagaatg atactaaaga
      601 attggaaaag caaatacaag taagttctgt agaaagtatg aagagtatgc tgggatgtct
      661 tatagttttg gttcaaatgc cagtagtata tgctttatat catgtatgtt tagatatgac
      721 aaaggaattt acaacaatta taattccatg gattgctaat ttaggtacat ttgataattt
      781 gtttatatta ccttgtatat atacattaat tatgttagct tcaaatttag tgaattatat
      841 accatattta aaaataaatt ctcaagtaaa gtttaacaaa caaatggctg tggtgactac
      901 cataacaagt cttatactaa ctgttagaac tccagtagcc ataggtctgt actttataac
      961 aagtgcaatt tattcattaa ttgaagatat ttgttttaga atatatttta atcgaaaaaa
     1021 tagaatagtg acaaaataat ataattatta ttagaaatat tttagcctgc taacatagaa
     1081 aaagttagta ggctattttt atctatgata tcaattccat taagaatagt ctaaaaaata
     1141 ctatcaaaat gctatcaaaa tactataaaa aaatagttga aaaataaata aattaatata
     1201 aactaaaata aagcctacaa aaaagaggtg ataaatagaa atggctaaaa tactaattgt
     1261 agaagatgaa aaaaggatgc aaagtattat tgtagaatat atgcaaaagg gaggatatac
     1321 ttgtataact gctgatgatg gagtcgaggc acttacaata ttaaagagca acaatataga
     1381 tttaatgata ttggatatta tgatgccgta tttagatgga ttttcagtgt gtagagtttc
     1441 acgtgaaatg actaatatac ctattattat attgacagct aaaggtgaag aggaggacaa
     1501 attaaagggt tatgaatatg gcgcagatga ttatataaca aaaccattta gccccaaagt
     1561 acttttagca aaagttaatg ccttgttacg tagatacact actgatattc ccaaaaattc
     1621 attgagttta ggaaagattt ttattatggt agcatcaaga caagtgtatg tagaagataa
     1681 attgattgat ttaacatata aagaatttga attattgcgt ttatttatgg aaaaccctaa
     1741 tcaagttttt tccagagaga aacttttaaa ttgtatatgg ggatatgatt ttgaaggaaa
     1801 cacacgaact gtagatacac atataaaaac cttacgcaaa aagcttggta gtgaaggaca
     1861 ctatatagtt acattaattc gttcaggata taagtttgag gttaaggaat gaatagttta
     1921 agaaagatta tagaaaaact gaaaaatgta gatatttcaa attggattaa acaaaatttt
     1981 ggactatatt cagttagaaa aaaagtgttt ttactttcta aattatcagg agcgttaatt
     2041 atattatttt atctggttgt tgaagaattt tcgataaact ctaaattaga attttggatt
     2101 tggtttataa tactggttat atttattatg agtattgatt tcttattggg aaaatttatt
     2161 tcagaaccaa tcacatctat aaataaatct gcaaaaagta tgtcccaact tgatttttct
     2221 aatccatgta ctgtaaatac taatgatgaa tttggagaac tttctaggag cctgaataca
     2281 atgtctacaa atctacaaca ggcattatca gacctagaaa gtgcaaatat tcaacttgaa
     2341 aaggatgtaa ataaggaaag aatgctattg gaacaaagaa aggagttggt agatacaatt
     2401 tcacatgaaa tgaagactcc acttggcatt atacgtgcgt atacagaggg gcttatggat
     2461 gaagttgatg aagaaaaaaa gaaaaattat atgaatgtta taatagaaga aactgataga
     2521 atgaacaata tgattgtatc attattagac ttatctgcat tggaagcagg agtttctaaa
     2581 cttaacccag agcgttttga ttttatagag tttgttgaaa ctgtggcagg tcgtctttta
     2641 attgatatac cagatgccaa tttttatttt acatatgatt tgccagagta tgaagttttt
     2701 gtagtggcag ataaaatgag aatggaacaa gtagtagaga atctagttat taatgcaaag
     2761 aagcatgttg tatataatgg taatttagat ttatcgatta catgtgaaaa tggcttgctt
     2821 ttatttgaaa tttataatga tggtaggttt atagagcaag atgagatttc aaagatttgg
     2881 tctaagtttt atcgtagtgt tcaatctcag cgtacaggag gttcaggcct agggcttgca
     2941 attgtttcac aaatacttac aatgcaaggg ttagaatatg gagtgaataa tcgtgataga
     3001 ggagtagagt tttattttat gattccaatt gatgaataat ttagtattaa tttataaatt
     3061 ataagtatct gatgtaaaat atttttcttt gtatatgtaa gcatttaaag agaataaaat
     3121 aaaaaaactt aatgaaaaaa gcttaatgaa aaagtctaat aaaaagctta atgaaaagtc
     3181 ttgtttttct gatgaaaaca agatttttta ttaagctttt tattatttca cttcgatttc
     3241 acaagagaga cactctgatt tcaccaaata gaaataaaat aggttaaata aattaaaaaa
     3301 tagaagcgta attaaataag gttacaaggg ggagtactta tgaaatggta tacatggttg
     3361 actattatat tgataatatt gctttctatt ccgcttaaaa ttaaatttat aaaatggtgg
     3421 gatagacgac aaaaaaatga taaaggaggt tatgatagat gataaaagta agagagttaa
     3481 aattttctta tggaaaagat aaacagatat tgcatggact taattttgaa gtaaaagaag
     3541 gagaaatctt tggattcctt ggacctaatg gttcaggaaa atccacaaca cagaaaatct
     3601 taaatggtgt tttaaaaggt tacaatggtc acgtatccct ttttggtaag gaagttaaag
     3661 catacacaga atctttatat caaaagattg gtgttttatt tgaatttcct tatttatata
     3721 ccaatttaag tgcaattgat aatttagaat atttttcgtc tttttatcct aaaaatcaaa
     3781 ggagagacat atatgaactc ttagatttgt tagagtttaa gaaagagttt ataaataagc
     3841 ctgtatcatc ctactcaaaa ggtatgaagc aacgtattag catggcaaga gcattggtaa
     3901 gtaatccaaa gttgttattt ttagatgagc ctactagtgg acttgaccca tctggggctg
     3961 tactatttcg taagattatt gaagaagaac gaaaaaaagg aacaactatc tttttgacta
     4021 ctcataatat gctagatgca gatttaatgt gtaacaatgt ggcttttatt gcagatggaa
     4081 agattatggt aatagataaa cccaaaaatt taaaaatgaa aaatagcaat aataaagttg
     4141 aagtggaatt tgcatataat ggaaatcgag atattgaaat tgtagatata caagagttag
     4201 aatctggaat aacttttaaa tatgatgaaa tcttaagtgt acattcaaaa gaacctacac
     4261 tagaagaagt ttttattaaa tacacaggaa ggatgttagt gtaatgtatt ctaaattttt
     4321 taccttagta aaaaaagatt tttggatgat gatttatggt aaattttttg tgctgacact
     4381 tggttctctc atactttatt cgtgttatat taattttggt tatgtaaagt ttatggatga
     4441 agatagttat cacaataatg tatatctata taatccagag aatataagca tgagtgcatc
     4501 tccattaatt aatcaagttt cttctatagg tgaattaaaa gcaaaacttg atgaagatac
     4561 aagtgcagtt tgtattgata tgagttccag taagccgaaa gtaattttac atgaaagtat
     4621 taaaggagtt gacaattata gagctgacta tgcattgtca ttattatcat cagaaaaaga
     4681 ccataatagc aaaatatcag acaacaatgc aataattcaa attaatgata aggatacatc
     4741 tgagataaaa caaagaaaag acatgacttg tgagatttta ttctttgaaa ttgtagctat
     4801 tggattttta gggattgcct ctttattatt taaagaaaag cagatgggag taatgcgtat
     4861 tactggtatt ttacctgtaa aaagaagtct ttttatatta tcaaagatat ttgctttttt
     4921 tatatgtgac ctatgtttta cagttctttt agtagtattt aatattggat ttttagaagg
     4981 aataaaaata cttccacaag tattagttca agctagtatt ttatcaatta ttatgtcttt
     5041 gattggaata ggatgctcaa tgttattgag agattttaag caattttctc ttatatatct
     5101 tgtggttgct gtattcataa ctacacctat atttctatct gcaaatacat cttttgaaat
     5161 agattggatt aaataccatc ccttctatca tgtttatagt cagcttaaaa atgcgttttt
     5221 catgaatttt tcaaaagaat tagtttattt tgtagtgtgt tctttgacaa taatagttct
     5281 atttttactt gtaaaatata tttttaataa agaattggtt agggagggat aatcttgata
     5341 ggattacgtt accagttaaa gagtataaaa aaagataaaa tgtgtataat ttccttcttt
     5401 ttaccagttg ttatggcgat tttaataaat tttatgggaa caattgatat atcttcatta
     5461 ggagagatac gttttggtat agtgaaggat acacttcctg tacaaacaga gcagtggttg
     5521 aagaagtatg gtatggtaag tgtatatgac acaaaaatgc atttaatacg tgaaattaag
     5581 gatattaaaa cggacacaat tggagttgtt agagatggta aaggaataaa aactgtgctt
     5641 tatggaaatg agattaatgc tataaaaaat gttggaaaga cattgccaga gatgtttaga
     5701 ctaaagggtg atttaaaaga tgttgaggtt acaatattgc ctaaagatag tattttaaaa
     5761 gagtttcaaa atgtttttat tgctatgatt ttaattactg ctatgtttat gggatgcacc
     5821 tttaatgcaa tgaatattat atctgaaaaa gaagatggaa tatcatttat aaatgaagtt
     5881 ttgccacaga gtagaagtca gtatattata caaaaagtat ttttgggtct tttatgtggg
     5941 tgtttatctt caatgataac tgtatttata tgtttggata tttcaatatt agatatgata
     6001 atgatgttgt tactcgttgt attttcagca tttatttcat cacttatagg tttatttatt
     6061 ggaaagttgt cagaaggtct tatggtagga attgtttata ttaaaatagt aatgatttta
     6121 tttataggta ctcctttgtt aatatatctt ctaggggtta ataccagcgg tatagggaat
     6181 ttatgctata taatgccatc agttgctaca tttaatggta ttatggagat tattaatggt
     6241 aatgtcatta ttataaaaga tattgtaatt ttggctgtac attgtgtagt atggtttatg
     6301 atatatatta ttttagataa aaaaagaaag ttatctttta gtagataact cagtataatt
     6361 ataattggga caatttaata ggtgatttaa tatactttgt atagtgtaat ttatgtagtg
     6421 caatttgtat actttaattt atgtagtgta atagttagtt ttattttata attattcaat
     6481 ataatttagt aagaagttca gtacaattag agctacttag tggaaaactt aataggtact
     6541 taaactatat aaatacttta ttttcctcca tttgtactat aaatttaatt tatgatataa
     6601 atggaggtat tattatatga tttgataaat ttcatcatta taacctacaa gtaaaggtat
     6661 tattatataa agttaataaa gatagtatca aaatattatt tgctataaag agagggactc
     6721 aaaataaaga taaacctatt tttcaatgtt gaaatgataa aatatatttg atttcatata
     6781 aaaaattttc ttcataaatt aaaaggtcca ttttaagcca cctcattttt aaccagataa
     6841 atcgagttaa actatttaaa tatattactc ggattcattt gacttagata ttccttgctt
     6901 gtaaaattgt tttgaatagg ggatagccaa agcaaaaaat aaaagtataa ttcctgctat
     6961 gattattaaa ttattaatag aaattacatc tgccattggt ccgaaaatca tcataccaag
     7021 aggaataaaa ccagtatata taataatagg taagctaaga actcgaccta gcatttgtgg
     7081 tgctacatgc tcttgcaaca tagtcatagc tgatgcttga atgattggaa ttgaaaaatt
     7141 cgtaaaaaac ataaatataa aaaattgcca agcttgtgtt acaagaccta gaataattga
     7201 aaaaatagca taggataata ttgctagaaa aaaggtctta tttctatttt taaaaccacc
     7261 aaaaactcct ataatcaatc cacctaaaac catacctaaa aatccaatca tttcaataat
     7321 agacaggtat atataaccct tgccaaatgt tcgttcaata agaagtccta taagaaatcc
     7381 tgatggaaca caaagaagca tgaatgctcc ataagtaaaa agcacttttc taatgaactt
     7441 atctgaaaaa cagtacttta tccctgatac catatctgca aaaaatgaga ctttttcagt
     7501 ttgttttggt atatcatgtt taggaatttt gatgaatatc aataatacaa tagcaataat
     7561 tgcagtaaat acatcaatta aaagaacttg atttatttta ttaccaaatc caagtattgc
     7621 agcagctaca ataggaacta taaattgtac tatagattgt aggctactat ttataccatt
     7681 aaaacgcatt aaatgttctt ctggtacaag ttgaggaatc attgcgttta cagcaggtgt
     7741 ttgtacacca cttcctagtg aacgtataac agatattact gatatggcta ttaattcact
     7801 tgttgtgcca tttgatgaca tcataaatag aattagaact aatgtagata tagcaattgt
     7861 tgaatctgat acaattatga gtacctttcg attgtagtag tctgcccata caccagcaaa
     7921 aaaagaaatt atcatttgag gtataaagga gcatacagtt aaaactgtta cccatacacc
     7981 tgatgatgtc tgaagtgtga cataccatat cattgccatt tgtacaagtg atgagccaaa
     8041 taaggaaata tattgacttg ctaaaaaaag aatgactttt ttcttccatg tagaattagt
     8101 atttttgttt tccatcctat tcctcctttg atttgtgtgt tgaatttttc ttgctcttaa
     8161 ggataacaca caaatcaaag tctggagtta gagtggaggg ctaggaaaat tgttttttca
     8221 taatttgaag atgagatttc atggtttttg cattatgttc agcttctttc aatgaagtta
     8281 tcagtttgtc acacactgag ataatttcgt catcatcttt tggagtgtca aggacagttt
     8341 taatattagt attaggatta gaagataaag catttaacat tcgtaaaata gctgaaagag
     8401 aatagtttgc acaacgaagt gcgcttataa ttttaagtcg ttttatatct tcatcagtat
     8461 atacacgata accattttgt tttcttttta cttttaacaa accattcatt tcccaatttc
     8521 ttaaagtatc tattgtaacg tttaagtgtt ctgcagtttc ttttctagtt aaaaagagtt
     8581 tatttgtttc tggagtattt ccatttaaaa tctgtgcaac aatagtaagt gcttcctcgg
     8641 cattagattt ttctatttct aattgttgca agtattgatt tacaagacta atagccttat
     8701 caaagtccct attcgctgat gttcttacaa tctcaagggc atcttttctt aatccccttt
     8761 gtaccacttc aattttcaag gctgtacgag caaatctaaa ttgttctata tgaaaatcat
     8821 taaagatacg ataaccattg gtattacgct taggtttagg tattaagttt agttcttcat
     8881 ataaacgtac tgtattagga tgtacaccaa ttaaatctgc tacctctgat gtcgtgtaag
     8941 tgtccattag tattcaactc cttttagata tatagtatta gtcataataa caccaaacaa
     9001 aagtctggtg ttataatgga gggtttggtt atctaagagt aattaattta tgaaagagta
     9061 attaatttat gaaagagtaa ttaatctatt atagaagtaa gtatatattt ttcaataaac
     9121 tcccatctat cacgaggttt aaacactatt ttagatggta tggctattac taagtcatat
     9181 tgtggaatac aacaaatagc atttcctcca gttcccattg ctgaatacca caaaacacca
     9241 tcttttttac atagccacca cagataaccg tattcattac tattcatttt aactgattct
     9301 tcaatccacg atttagatat aatacgttta ttattccaaa taccatcatt taaatacaga
     9361 aaaccaaatc gcaacatatc tctagcactc aatgtaagtc cccagccacc tatagaataa
     9421 ccctgtctat cttttgccca acccttaaga ttttttccaa agaaatcttc aaaaccaaaa
     9481 tctttcatat cataatctgg tataattttc ataccaatag gtttaaataa gtattcatta
     9541 gcaaattcac gagcagattt tccagtagtt tttgttataa tagctgaaag taggtgcgtt
     9601 ccagctgaag aatatttgaa agtaccaatt tcgccttttt gaccaagttg attcaaggta
     9661 tattttatcc aatctttttg tttgcaaagt ctttctaaag actcagtcat atttttaaaa
     9721 gggtatggtg cagtcattgt aagtaggtga cgtatagtta ctgctttttt acatatttca
     9781 gaaggactac aagtatattc agggaaaaaa tcaacaacct tttggtcaac atcttttata
     9841 tatcctttat ctattgcaat acctattaag gctgatataa tactttttgt aactgatgca
     9901 acatgaaaag tatcatcagc attatatcca ttatagtact tttcaaagac aacttttcct
     9961 tttcttgcaa taattattcc atttatatta ctatattgtg agattattaa aggttcaagt
    10021 tgtgagagct tttctgaact catgccaaca cttgaagggt ctactttttc aaatattaaa
    10081 tctaagcaat tgtttttatt cattaaagat acctccctgt tatagatttt ggattttctt
    10141 ttagagtttt tggagaacct tctgcaatta tataacctcc tttgtcacca ccttctggac
    10201 caagctcaac aatccagtca caaacattta atacatctat atcatgttca acaacaatta
    10261 cagaatttcc attttcaacc aattcatcta ataattgaat caacttagaa gtatcgtata
    10321 gacttagacc agtagttggc tcatccaata cataaaggat attaccattt cgttttttac
    10381 caatttcttt tgcaagtttg attctttgag attcaccacc acttaaagtt ggtgtaggtt
    10441 ggcctaattt tatatacccc atacctattt gttctaatac atttaagtgt gaaacaatat
    10501 ttggaatatc tttgaagaaa tgtacagatt cagaaacact catatttaaa atatcatgta
    10561 tatttttatt tttatattta atagataaag attcatcatt aaatcttttt ccctgacatt
    10621 cactgcatat atggtctata cttagattat ttcccaacca gaccttttca tatccactac
    10681 cactacattt aggacaagca cctttggagt taaatgagaa atgaccagct gtaaatcctc
    10741 gttctaacga ttctggctga cctgcaaata gtgtacgtat cttatcccat ataccaatat
    10801 aagaagcagg agttgagttc atatttttgc caataggaga ttgagatatc tctgaatatc
    10861 cagaaatatg tttagtacca atcagtctat ctgcaatagt ttcaacaact gcataatcgt
    10921 cttcctcacc tatttcactc tctgaagaat ttgtttgatt attgatagta tggttattaa
    10981 attggcttct aagaagagga agtagggtgt ctgatataag tgaactcttg ccactacctg
    11041 attttccaga tattccaacc atagcaccca aaggtaatga tacagttaca tttttaagat
    11101 tatttgtatt tgcattttga atagttatac aaggtatttt atcagtatgt gtaatgtttt
    11161 tattgcttgt tctattaggc attggatatt ttccagatag atactgtcca gtaagtgatt
    11221 tgtcggattg aagtagacct tctaaatctc cttgatatac taattgacca ccttcaacac
    11281 cagcctttgg accaatatca ataatatgtt ctgccatttt aattgtgttt ttatcatgct
    11341 caactactat gactgtattg cctaaatctt taagtttctt tattgatttt aagatgtcta
    11401 ttttttctga ttcatgcaat ccagctgttg gttcatcaag cacataaatt aatgagtcca
    11461 tctctgaatc gagatgtgaa tttaaaaata gtctttgcat ttccccacca ctcaaagttg
    11521 acatttctcg gtataaggat agatgaccta atcgtgattc tattaaatgt tgagttttgg
    11581 ataaaatatc atttacaaga tttgtaccaa atgtgtttaa attaccttga tttattaaga
    11641 gtttaaggaa atcatcaatt tctaaaatcg tcatttttcc aagttctcca atatgttttc
    11701 cgtttaaaag tactctacgt gcttcttcac caattttaaa accattgcaa tctgaacagg
    11761 cagtcatagt ataaactcca tttaaatctt cgcccctttt gtaacgattg tgaaatacct
    11821 ttgataaaga ggaacttttt ttaccatttt cataatgacc atagagtact tcatttctta
    11881 tttcttcagg tagttgtaag aattgtatgt ctaaataatc gttgaatttt ttagaaaata
    11941 ctctcaaata tcctggtgta atctttgctc tatctaagac ttgttttagg gtgtcatgct
    12001 tatcaaggac taatttttca atattaatct caaaatatgc accatgtcca gagcacttca
    12061 tacacattcc atctgaagag ttgtatgaga aataacttgg tcttaatcgt tcttcctcat
    12121 atccacaatt attgcaaatt agattatcgc ttacaggagt atcacacata gtacacatta
    12181 tttgaccttc cactgaatac aatagtgtaa gcatgttgag aatattggtt cttgtgccta
    12241 ctgttgaacg aggattgctc tggcgaataa tattttgttg aacagctata gtgggagcta
    12301 aaccttgaat attatcaaac ttatcttcac tatcaatacc tgcaagtata cctaaagatt
    12361 gcagatattg tttacgccct tcctcaaata caatgtcaaa cataaggcta gacttacctg
    12421 agccactgac acctgttgca acaacaagct tatctttggg gatagaaaca tctatatttt
    12481 taagattgtg tatctttgct ccattaattt ttatttcttt cattggttca cctcatttta
    12541 tcaattttat caaaccgtaa aatagggata tattaatcct taatacaaga atagattagg
    12601 tgaggttatt aaaaaggttc tataggtaaa tatatatcga ccaagtgtct attttgaggg
    12661 tgattgtgtg ggttgttaag atatacttca aaagggaagg aggcacgtag cttataatta
    12721 ccatttgata gccattcatt atacataaaa tcccacgcat cactatattc agattttgaa
    12781 atatcaaaat gtcccacaag atattttcca gaaggtatta tcatattgcc aagattgtca
    12841 ttctctttga caactatgtt atctggaata gtcatgcaaa tactagtcct taattgatgc
    12901 tcctgtgtaa attgtggatt atcatgataa atggctaata tttgtgtgtt ttcaagtcca
    12961 agtagattct gctcacttgc atatgtgaat aaccgttcta aaagttttgg gaaagtactg
    13021 gttagattac catatgaacc agtataccta gtgtaaatag tattcatatt atcaagttct
    13081 agaatttcaa tttcaccttt aacctctcta gtattcttac atttaggttt tgatatgctt
    13141 ctattgtact gagaaatttt atatggttct ttgcaattct tgctataatt gtttctatat
    13201 tttatagggc ttattttata gtaattttta aatgctcttg agaaaactgc tgaatcagta
    13261 aagccaaagt agtgtgcaat atcagtaaca gtcatgtcag ttctatgaat aagaaaagca
    13321 gttgcatttt ctagttttag cctatttaca tattgtgcca aagtttcttt ttctattgct
    13381 ttgaagattc tatgaaaatg aaattttgaa aaacctgcta tattagaaag ttcatcaaga
    13441 gaaagaggtt catgtaaatg ttcttctata tagtcttgca ctttgcaaat acgatttaga
    13501 tattcttttt tacttttagc atttgtcata tataaccctc cttattgtgt aaaatgtgta
    13561 tcaattaatt tatagcaata tagtaataaa attttatgtt tttgtaattt atgataaata
    13621 agatagcgtt taatttttta taattgataa aagatattta taattgataa aagatataag
    13681 atgccttata tttgtctttg catataagta tagtcttcgt aataattagt ataccatagt
    13741 gatttatttt taattgtgta tttatataaa tacacaactt atgatatgga cgaattatta
    13801 tgcaaataag ctgtaattaa ataaattgca atataaacca gttgaaacat aagttaggga
    13861 aatattatca aagtta
//
LOCUS       DAEQAF010000095        13711 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.098, whole genome shotgun sequence.
ACCESSION   DAEQAF010000095 DAEQAF010000000
VERSION     DAEQAF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13711
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.098"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            31..777
                     /locus_tag="KRN00_002979"
     CDS             31..777
                     /locus_tag="KRN00_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBH1828834.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHVELEHSDYLEQLINSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKFYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            838..1512
                     /locus_tag="KRN00_002980"
     CDS             838..1512
                     /locus_tag="KRN00_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBH1828835.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKRESIIDVSKCFCVLKCMMSCPWSL
                     RYANQK"
     gene            1880..2961
                     /locus_tag="KRN00_002981"
                     /pseudo
     CDS             1880..2961
                     /locus_tag="KRN00_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
     gene            3099..4043
                     /locus_tag="KRN00_002982"
     CDS             3099..4043
                     /locus_tag="KRN00_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBH1828836.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLEEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGITLEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRL
                     YKEGNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            4212..5144
                     /locus_tag="KRN00_002983"
     CDS             4212..5144
                     /locus_tag="KRN00_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBH1828837.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKVK"
     gene            5249..5716
                     /locus_tag="KRN00_002984"
     CDS             5249..5716
                     /locus_tag="KRN00_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBH1828838.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(5960..6814)
                     /locus_tag="KRN00_002985"
     CDS             complement(5960..6814)
                     /locus_tag="KRN00_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBH1828839.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSSKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSSIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VFMLSIIK"
     gene            6980..8944
                     /locus_tag="KRN00_002986"
     CDS             6980..8944
                     /locus_tag="KRN00_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1828840.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVASDQHRDTNELKNTSTNPCETNTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAIKYITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            8944..9405
                     /locus_tag="KRN00_002987"
     CDS             8944..9405
                     /locus_tag="KRN00_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1828841.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            9408..9728
                     /locus_tag="KRN00_002988"
     CDS             9408..9728
                     /locus_tag="KRN00_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBH1828842.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            9744..10844
                     /locus_tag="KRN00_002989"
     CDS             9744..10844
                     /locus_tag="KRN00_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBH1828843.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            10964..13564
                     /locus_tag="KRN00_002990"
     CDS             10964..13564
                     /locus_tag="KRN00_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBH1828844.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKSRENVLEETPAGNIFIEEPGYYILKVR
                     INIQLPALGYKVVSFESSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDEDIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRENGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         5452 a         1451 c         2320 g         4488 t
ORIGIN      
        1 aaatgtaaac tgtgaaatgg aggtagtaac atgaaaattg aaaatctttc tattgatgat
       61 attaaacgag gctatatatt taatgatgat ttaaattgtt atagttgcat taaatgtaca
      121 aaaacatatg aggtaggaga aatatataaa ataggtaata gattctttga agcttcaaaa
      181 gctattgaac ttcatgtgga attagaacat agtgattatt tagagcaatt gattaatagt
      241 gattcaaaat acaacacatt gactgaaaat caaaaacaat tatttcaatt atttattagt
      301 gatttaccag ataaggagat agcaaaacag gttggagtat ccacatctac tatacgccat
      361 caaaaattta ttttcagaga aaaagcaaaa caggctaagt tctatttagc actatatgaa
      421 tctgtatttg aagataaatc taataaaagt agtactataa taccaatcca tgaacatgct
      481 cgaatggtag atgaaagata tgtagtaact gaagaagaga gaaaacacat tttggataca
      541 tcatttgaaa gtatgaatcc tttaaaatta aaagtatttt cttcaaaaga aaagaaaaag
      601 gtcgtaattt tatctaagat tttggaacaa tttgaacgtg ggaagaaata ttcagaaaag
      661 gaagttaatc agattttaga atctatatat gatgattttg caacaattag aagatatcta
      721 attgagtatg gttttatgag tagaaataaa gaatgtacaa aatattggtt aacataatta
      781 aaataataaa ttttactaat gtgtaatgtt atttttatct agggggagga gtcaaatatg
      841 aatgatgaat taaaatctat tttatacaat aaaggtgtgg acattgttcg ctttgttgat
      901 atatctgaat ttccaataaa tcaaacgcaa ggtttttcta aagcaatttt attttgtata
      961 ggattatcaa aaaaatttat tacagatata tacaataact tacctacaga tagtgatgag
     1021 tttttggaaa aagaggagaa agtagaagaa ttagctgact ggatttcaaa atatattcaa
     1081 aataaaggat atagagcata ttctcaatcg gagaaaaaca atctagaaca tggatatttt
     1141 gaaaaagcct atattaatcc agaaatgcaa tcagggatta gtcctttacc acataagaca
     1201 atagcaaata ttagtggcat tggatttatg ggaaaaaata atttgtttgt aacagaggaa
     1261 tatggatgtg cttttagcat gtgtacagta cttacagatg ctccaatttc tgttgaaaga
     1321 tatcctttga ttgattcaaa atgtatggat tgtaatgttt gtgtagaaaa ctgccctgca
     1381 aaagctatac atggaaatga gtggactttg ccaggaaaaa gagagtctat tattgatgtt
     1441 tcaaagtgtt tttgtgtatt gaagtgtatg atgagttgcc catggtcatt aagatatgca
     1501 aatcaaaaat aattttacta gagaaggtat taaattgaat attataaaat ttttaaaatg
     1561 taagattata taagattttt caaaataaaa atttgtatag aacactcaga aatgagtgtt
     1621 tttttattgg aattaaatta tattgataca aagtttaact attttaatca ttatataaaa
     1681 tttgtattaa aaaattaaga ataacttggt aatagtgaaa atataatgag attttaaata
     1741 atttataaca aaattataat aatattttaa aaatgaaagt tatcttctca aaattcctaa
     1801 agatagtaaa aggcacttca gttatagttc aaaactgttt ctgtgagaag aatttagatt
     1861 taaaaagaag gaattaatca tggaaattga aactaaaact cctgattgga ttaatgtact
     1921 agaattaaac tgtagaatga atgttactgg gaaatataat gtaagtaata tgatacaaga
     1981 tattgtctct gataagtcac taaaaggttc tattatatat tttccaaaag gtaaatacct
     2041 atttacaagt ggtattaaaa ttaataaaga aattgtatta caaggtgatt ctaatttatc
     2101 tacaggtact acacaattta taactcgtgg agtagaaaat atgagtatta ttacattgac
     2161 agggaagaac aatgtattaa aaatataaat ttctattctg atagttgtga gatacaggta
     2221 aataaagaac caccgacaaa aggtaatcct aaatatcatt atgagatgat tattaataag
     2281 aatgaaaaga atgttgagat gaataatgta tcagcaatcc tgtatgataa cagtaagaat
     2341 atgattaaag gtctaggtca ttatgaaaat atttatataa gtggtttttc gggtacagga
     2401 attaggatac catattactc aattgtaaat gatattacag tttcatcttg tgggctgggt
     2461 attgatacag gaatagacac aattatttct aatagtagaa tatctaagtg tcaaaatgga
     2521 atgaggatta gaactggaac tagtataaat aatgtaagga ttgaaaaaat acagaaagtt
     2581 ggtcttataa gtagtcaagt taagggggat gaggggtatg gaagttataa aattaataat
     2641 attacgattg accaatgtgg gtattgtggc ttttcatttg attcaatgaa agatagttat
     2701 ttttctggta ttataagaag gtgtggtcag tattattata atacagatta tgacacatat
     2761 ttaagcatta aagatagagt agaagaagca tattctttat tttatggaaa ttattttaca
     2821 gaatgtaata ttgatttagt tagtgataat aaggataact gggatgatgg cttagaatat
     2881 aaacataaag tttatgtatt taaaaccctt caaatacaaa agttaatatg taatatagat
     2941 gcctataatt atatcattaa attatatttt aaattctaga aatgagtcag taaatcttgc
     3001 tggaattatc ttagatattt tgattaaatt aagtacttag agttataatt atattaaaaa
     3061 tatattagaa cataattata ttactatgga ggttaaatat gatagtaagt gtgagtagaa
     3121 gaactgatat acctgctttc tatagtaagt ggttttttaa cagacttgaa gaaggttttg
     3181 tttatgtaat taatccaatg aatccaaaac aggttagtaa gatagagtta aatccacata
     3241 ctgttgattg ttttgtattt tggacaaagg atgtaactcc aatgttatat gatttaaata
     3301 aattaaaaga ctataaatat tattttcact atactataac atcatatgga aaagaagtag
     3361 agacatgtat tttagataaa agaaaggtaa tagattcatt taaggaattg tctagaaaaa
     3421 taggcaaaga aagagtaatt ttaagatacg acccgatttt cttaagtgaa aagtacacag
     3481 tagattatca tatcaaagca tttgcgagtt tatgtaatca gcttgatgga tttacagaaa
     3541 aatgtataat aagttttatc gatttataca agaaaacaaa atttaatact aaagcattac
     3601 atataaagcc aatagaaatt acagaaatag aaacattatc aaaagagatt tctaagattg
     3661 ctcataagca tgggataaca cttgaaatgt gttctgaaga atataattta agtaaatttg
     3721 ggattggaaa aagtaagtgt attgatgata gattaatatc aaaaattata ggatgtgaag
     3781 tagaggtaaa aaaagatagt acacaaagag atatttgtgg atgtgttaaa agtgtcgata
     3841 taggacaata caatacttgc agacattatt gtctgtattg ttatgctaac tttaattatg
     3901 caaaagtaga agaaaactgt aggctttata aagaaggtaa taaattactc atagatactt
     3961 taagagatga tgcaaaaata agcattagag atatgaagac tattaaagta gataagaata
     4021 aacaaattag tatatttgat taaaataaat atactaatta ccttaatata ttaagaatat
     4081 agatactttt gataacaaaa ttaaacttaa tagatatttt ctatataaga aagatggtca
     4141 taatatgtca atttgaccat ctttttgata taattaaaac acaaataatt tagtaacaaa
     4201 ggaggcagaa cttgaattta ttaaaaaaat atcctatacc tattgcaagt ttgattttat
     4261 caatttttac tttaggtaac ttattacaat cttatagtga atcattacgt aatgtaattg
     4321 gatttatagg atttattttg tatgcaattt atatagtcaa aataatatta cttagaaagg
     4381 gtgttaaaga gcaattagag aaccctttaa tatcaagtac atttccaact ataacaatgg
     4441 caacaatgat atttgctaca tatataaaac cattatcttt agaattaagt attatgattt
     4501 ggagcatagg aattgtgggt catcttgtgt taatagtctt atttagtaag aagttcttag
     4561 ttaaattctc aataaaaacg gtatttccat cttggtatat agtatatgtt gggatagttg
     4621 cagctagtgt tacggcacca gcatttaatc aacttttgat tggcaaaatt gctttttgga
     4681 taggatttgt atcttatata gttcttatac cagtaatttt aaagagagta tggataatca
     4741 aggaaatgcc tgaaccatct ttaccaagta tagctatatt agctgcacca gggtcactat
     4801 tattgtctgg atatattaat tctttttcag ataaaaataa tgtagtatta tacttgttat
     4861 tcatattatc aattgtattt tatattatag ttttgggata cttaccgaaa ttattaagat
     4921 tgccttttta tccgagtttt gctgcattta cattccctat ggcaataagt gcaatgggta
     4981 tgaaactaat gaatggttat ttaactaaat caggtcattt tataagttgg atttcatatg
     5041 cttctaagtt agaagagata attgctacag tgattatttt atatgtttta gttttgttta
     5101 ttatatatct tagtaaatct gaaactacat ctaaagttaa ataagaatta ttaaatatgt
     5161 gtatttaata ggaatattga tataaatata tgaagataag ataaaccata gaaacttaat
     5221 ttagcttaat tttattggag gaaaacaaat gaaaacaaaa gaagaatatt taaaagaagt
     5281 tagaaacata tcagaagaat actttagaaa aggagagttt ttttgctctg aagcagttct
     5341 ccagacaata aatgatgctt taggccaacc tttaagtcca gagataacta agttagcatc
     5401 aggatttccg ataggacttg gaaaggcaca atgtctttgc ggagcaatat ctgggggaga
     5461 gatggcttta ggtatagtat atggaagagt tcatggtgaa gctatgaatc caaagatgtt
     5521 tgagcatgct aaaggtttgc atgattatat taaaaaagag tatggtgcaa catgttgtag
     5581 agctattaca aagaaatggg atggtgataa ctttatgtct cccgaaagaa aagagcactg
     5641 tattaaaata acaggtcaag ttacagagtg ggttgcagat aagcttatag aagatgaaaa
     5701 acttaatatc aaatagtgta atattagttg gtgaatttat aaagttaaat ttacttatag
     5761 tataagatac ttgatattct cgtattgata gaaaaattta tagcatatgt atttaatgaa
     5821 atatacttat atttagagtg tggtttaatt tcataaatac atatgctatt attttaagta
     5881 tataagcaaa tttatttaaa taaatagaaa cagttaattt atatgtacaa aattatatat
     5941 gattagtgta aataaatacc tattttataa tactcaacat aaagacacca gacatgatta
     6001 gtattatacc aataaaaata gcaagccatt cttttttgtt cttcttttct ttaaaaaata
     6061 taatccctcc taaagtggct actatcacac aactctgaga gatagaaaaa cttattgtaa
     6121 ctcccaatgt attagtcgtt atgaacatac ctaaatttgc tattgaccac aatataccag
     6181 taattaaatt gaataaaaca ttttccctat atacaatctc tttagaaaaa tacttgacaa
     6241 taatagatga agttatcaac ataccaacag attgaggtaa tataattcta tatccttcaa
     6301 ttaaaaatat ttgattagtt acaacatata atgataaaaa tagagatgat aataatacaa
     6361 ctccaacaca ttttaacata tttttatctg tagatttttt agtttgataa tttgtgagaa
     6421 gtataccaag tattatacat aatattgata aagaaccaat cagtaacatt ttagaactgg
     6481 tccattcatt aaacaagatt acagctaata atgtcgtaaa agttaattgt gaaccatttg
     6541 aaattggcat tactttagat acactagcaa tttgaattgc tttaaactgc attaattgtc
     6601 ccaaactcca gaatatgcca gaaatcatac ttatacaaaa tgaaaaaaat gtaatttcag
     6661 gatgtataac cagagttatt atagtggaaa atataaacgc acttatggat gtacctaaaa
     6721 gctgttcatg aggagaactt ttctttagat ttgcaactat gggcatcaat ccccatccca
     6781 ttacaggaag taaagcaata attattgtca gcattaaact atttcctttc atattaaatt
     6841 tagacagctt ttaatttatc atctaaaatt aaagtgttca atacataaaa attaccgtat
     6901 ttaatcagga aatattagta gttttttaga aaaacatttt ccattaaaat aaagacaaag
     6961 ggaaggagta aaattgaaaa tgttaactga tatgattcaa aatcgtgaaa ttaaaataat
     7021 aaagttttta ttaaaagaag gtcatacaac tgtaaaagca atagcagatg atttagatgt
     7081 ttcagaaaaa acagtttcaa aatctcttaa agaagtagaa gcagtgctta aaaagatagg
     7141 tctttcttta ataagaaaac ctaagatagg tgtttatatt gatggagatt taaaaaaaat
     7201 acttccttac ctagataata aaggaagtca aattcctaca accagagagg agagagttat
     7261 ctatatatat tcagtacttt taaagagtaa tgattatatt actatacaac aactttctga
     7321 tgaactatat ataagtcgtg gaactattga aagggattta gcagaagttg aaaaactgct
     7381 aaaaaacgaa gggatttcca tatataagaa acctagtaag ggaataaagt taaatataag
     7441 tgaaagagat aaaagacaac ttactgctaa gtttatacat aaattttgga gtagaaactg
     7501 gtatattaag caagagcaag aaagctttta tcaagcattt gaaaagatac aggcagatgt
     7561 aaatggtatt ttttcggaag atgatttatc aataattatt gatattctta ggaatttcag
     7621 cagagaaaga aaatttgagt tctctgatta tgaatttcag tcattagtta ttcatttggc
     7681 aatagctgta gagagaatta gaaaaggcga atatatagaa gaaagtttgt atattggtaa
     7741 tatagaaaat aatcaaatgt caaataccaa ttatttagca aaacaattag aagaaaaatt
     7801 ttcaatatta ttaccaaaat ctgaaattgg atatataaat ttacatttag tagcgtctga
     7861 ccaacataga gatactaatg aactaaaaaa tacttcaacc aatccttgtg aaacaaatac
     7921 aaataatata tcaaatcttc gggaaattat aaaaaataca ttgtatgaga cagcttatga
     7981 caaggattta attgatggat taacttcaca tgtacattca tcaataaata gactgaaata
     8041 tggacttagt attaaaaatc catatgtaaa tacaatcaaa caaaactttt ctttatcatt
     8101 tgagcaagct ttagatttaa agaaagtaat tgaatttata tatgatatta ggataaatga
     8161 tgatgaatgt gcttatatag cattacattt tgaagctttt agagaaagaa tgaaagaact
     8221 tccacaaaat attagagtaa ttctagtatg cagtacagga ttaggttcat ctaggttatt
     8281 gtctgcaaga ataaaaaaat actttccaat gataaagatt gaaaaagtac tttccgtaca
     8341 agaattagta tccagtaaaa ttgatgcaga tttagtaata agtactattt atttagagtt
     8401 agaaacaatt ccaaccatag tagttagtcc tattttaaat gaaagtgata taagaacctt
     8461 ggaaagaaat atacaaaatg tttcaagttg tacttctaag aagtataaat ctttcagaaa
     8521 cttaatcttt gaagaaaata tattgttgaa tattgaagct tcaaattatg aagatgcaat
     8581 taagtatata acagataacc taataaaaaa aggttttgca aaagaaggta tagctaaaag
     8641 tgcaattgag agagaaaatt tatcttacac gtctttccag tcaatagcta cacctcatgc
     8701 taatcctagt tatattaaaa aatctaatat atctgttgca acgttaaaaa atcctattac
     8761 atggggaaat gaaaaggtgg aagttatttt ctttatttca ttagaaaatg acaaaaacct
     8821 agagcttgat gaaatatatg aagtttttta tgactttatt gacaataaaa aaaatataaa
     8881 tgacatatta agtgcaactt ccacaaagga agtgtacgat ttgctagtgg aggagagtat
     8941 atagtgaaaa tatcagatgt attgaaaaaa gagcaaattg tttttaatct tgatacaaat
     9001 acaaaggaag aaacaataaa aaaattaagt agtatatttg ttgaaaatgg gattgtggac
     9061 aatgaagaag aatatgttaa gtctgttttg gaaagagaag aacattcaac tacaggtatt
     9121 ggtaatggta ttgctattcc tcatgggaaa agtaatgctg tcaaaaaatc ttctataata
     9181 tttgcaaaga ctaagcataa gattgaatgg gatgctttag atgaaaaacc agtagatagt
     9241 attttcttat tggctataag caatattgat aaggatagca atcatcttgt actattatct
     9301 aaattagcaa ctaaacttat ggatgatgac aatgtagatg cactaaaatt agccaattca
     9361 gaacaagaaa taatcaatat atttagtgaa gaaggagaga tgtagaaatg aaaagaaaaa
     9421 ttatagcagt tacagcatgt gcaacaggag ttgcacatac atatatggca gcacaagcat
     9481 taaagaaagc ttcaaaaaag atgggtcacc ttataaaagt tgaaacacaa ggagctacag
     9541 gaatcgataa tgagttaact acaaaggatg cacaaattgc agaagtagta atatttgcag
     9601 tagatactaa agtcagaaat gctgaacgtt ttgagggaaa agaaatacta gaagtaccag
     9661 ttaatgcacc tataaaggat gcagagaaag taataaatga tgcattaaag ttaattgaca
     9721 ctaaataaat ggagggaaat gtaatgttga aaaagatagt ctctgagtta aaaaagcatg
     9781 tcttaactgg aatctcatat atgattccat tagtaattgc aggtgctatg ataatggcga
     9841 tatctcgtgt aggtggttct ttctataata taccagatat atgggatgct aaatatgcag
     9901 aaagtgctag tagtattgtt agattattac atgatttaga tgggtttgga ggtactgcat
     9961 taggattaat gtttcctgta attgctgcat ttataggatt ttctatagct gataaattag
    10021 ctattgtacc aggtcttgtt ggaggtatga ttgctaaaga tataggtgca ggatttttag
    10081 gagctttggc agttggtctt atagcaggat atacatgttt gtttattaaa aatcatgtta
    10141 aattaccaaa atcagcagct tcaatagtac caatatttat agtaccagtg tttgggacat
    10201 taatcactgt tgtattaatc aattatgtga taggtatacc ttttgccaca ttaaatactg
    10261 gattagaaaa ttggttaaat ggattatctg gtacaaatca gatactaatg gcagctatta
    10321 taggggctat gatggcagtt gacttaggtg gaccagttaa taaagcagct ttaacaacat
    10381 cacttgcatt attaacaagt ggaatttatg cgcctaacac tgctgcaatg gtaggaatag
    10441 ttataccacc actaggattg ggacttgcta ctatactagc aaaacaaaaa tataataaac
    10501 agttacgtga agctgggaaa tcatctctta taatgggttt aattggagta agtgaaggag
    10561 caattccttt tgcagtagaa tctccattaa aagtaatacc ttcatgtgta attggaacag
    10621 caattgcttc agctatggca gttggtttag gttcagtaaa tgcaactcca attagtggat
    10681 tttatggatg gtttacagta gagaattggc caatgtatgt gttatcaata gcagttggaa
    10741 cagtaattgt agctggatta gttatagtat tgcgtggaaa tccagtgatt gaggatgatg
    10801 aatttgaaga tgatgatttt gatgaagcag agtgggaatc ttaaaattta ataactattt
    10861 aagacgtgtt ataagctata ttcaatataa atcttatact aaataaagtg ttaaatattc
    10921 agtttagact taaatataaa agataaagaa cagaggagaa taaatgataa aagcacatat
    10981 tgttaatcat acacactggg atagagaatg gtattttact tctggagatg cattagtact
    11041 tagtgaacaa ctatttacag atgtaattga tgaattagaa cgtaatccag atgtaagttt
    11101 tgtacttgat ggacaacttt ctattttgga tgattatgta caattacaca aagaaaaaat
    11161 agaaatcatt aaaaagttaa taaaagaaga tagactacat attggaccat ggtttactca
    11221 aactgatgca ttctttgcta gaggagagtc tattttaaga aacttaatga ttggaatttt
    11281 tgaaagtaaa aagtatggta agtatatgaa aattgggtat ttgccagata catttggatt
    11341 taatgcacag atgcctatac tattaaagca tgtaggtctt gataatatat tcttttggag
    11401 aggtatacat cttggtaaac aggttcaatc accatatttt aagtggaaaa gcttaaatgg
    11461 agaaagttat atatatgcag taaatatgcc acatggatat ggaactggta tgcttttaga
    11521 gccttcatta aagtatgtta atggacgctt agacccagct attgatttta ttaaatcata
    11581 tactgatgta gatgaggtgt taataccttc tgggaatgac cagttaaata taataggtga
    11641 tttcaaaaat aaaattaaag cgattaatga tatcggaaag tattcatata taacgagttc
    11701 atatcaagag tttttaaaat atataaagtc catagaatca ctagaaagct atagaggtga
    11761 atttagagaa cctgtattag caagaataca taaatcaatt ggttctagta gaatggatat
    11821 aaaattagca tgtgataaac tagaaaacaa gctgattaaa agaatagagc cattattagt
    11881 aattgctaaa aagagtaaaa ttgaaataag caatcagtta cttataaata catggaaaaa
    11941 acttttggaa ggacaagcac acgatagttt agctggatgt gtaactgata ctgtaacaga
    12001 tgatattctt caccgtataa gagaagcaaa tgaaatatgt gacagtattg aaaatactat
    12061 tgtaaaaaag atttcagaag ggcttaaatt atctaaaaat gatattttag tattcaatac
    12121 agaagctaag cgttttaatg gatataaaga gatacaagtt gtaagtgata gtaaaaatat
    12181 ttattttaaa gataatttag atgctactat aattgaagaa acttatgtaa aatcgagaga
    12241 aaatgtatta gaagaaacac ctgctggtaa tatatttatt gaagaaccag gatattatat
    12301 attaaaagta agaataaata tacagcttcc tgcacttggt tataaagttg ttagttttga
    12361 atcaagtgat aaagaaatgg tgtcacttga taaatctaat gacactttta tatctaatga
    12421 taattataag ataatatatg aagatggaag cttaaattta caacttaaag atggaactta
    12481 catatcaaac tttttaacat taaaagatag tggtaatgca ggtgatacct atgacttttc
    12541 tccactaaaa aatgatgagg atataaaact ttcgtttgat aaagtgtata cagaaaaagc
    12601 tttaggatat gaaaaaatgg tggttaaagg tactacttta ctaccactta cattagaaga
    12661 tagaaaaaac aaatatctta atgggaaatt aaatgtaaaa gtaagtattg tcttatccaa
    12721 agaaaatcca ttgatggatg taaaactttg tgttgataac acaatatata atcatagact
    12781 acgtgttcat ataaaaactg atataaaaga taataaaaac atagcatcat tgccatttgg
    12841 ttatataaca agagaaaatg gagttttaga caactgggaa gatatttaca gtgaaatgcc
    12901 tatagattta gaacctttgg aaagtaatat tacgcttaca aaccaaaata gaagttgtac
    12961 tgtatttact agaggaataa aagagtatca acatattgaa gatgaaattg cattgacctt
    13021 acttgctact acagatgaac taggaaagcc tgatttatta tatagaccag gacgtgcttc
    13081 tggtgataca actaaaaaag gtcatataag aattaaaaca gataaagccc aaatgcttaa
    13141 ggaattagaa ttttcatttg caatatatat ggattctaaa tcatttgatg aattggaaat
    13201 tgcgaattta acccacaatt atctaaggga atgtgtaaat tatcaattac aggattacaa
    13261 tttcttttta tatcgtatag ataataagat tcaaaaatca attgtcaata aaactgtaag
    13321 tagagaatta gaaataatat ctttaccaga aaactatctt atatcagcat gttatccttc
    13381 ttattacagt aaagataaat ttataataag agtggaaaat ccaagtagta atagaatgat
    13441 attggatgag caaatattta aaaatagaaa tgggaaaatt gtaaatgcaa tagaagatgt
    13501 agaagaggaa caggtatatg aaatagcacc ttttgacgtt atttcaatat tattggattt
    13561 ataagtgtaa aagtaagttt attgtttaaa gtctgacaga tattaatctg ccagactttt
    13621 taatttgtat aaatttgggt aaatattaat gaatggtttt agtatttaag tatgaattta
    13681 gtatttaata tagaatttat tgaagtagaa t
//
LOCUS       DAEQAF010000096        13707 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.099, whole genome shotgun sequence.
ACCESSION   DAEQAF010000096 DAEQAF010000000
VERSION     DAEQAF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13707
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.099"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..703)
                     /locus_tag="KRN00_002991"
     CDS             complement(<1..703)
                     /locus_tag="KRN00_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBH1828845.1"
                     /translation="MGKVAKILLSLIVIVLVLAGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKT"
     gene            995..2659
                     /locus_tag="KRN00_002992"
     CDS             995..2659
                     /locus_tag="KRN00_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBH1828846.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(2766..3665)
                     /locus_tag="KRN00_002993"
     CDS             complement(2766..3665)
                     /locus_tag="KRN00_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBH1828847.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(3692..4330)
                     /locus_tag="KRN00_002994"
     CDS             complement(3692..4330)
                     /locus_tag="KRN00_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH1828848.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(4667..5665)
                     /locus_tag="KRN00_002995"
     CDS             complement(4667..5665)
                     /locus_tag="KRN00_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBH1828849.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFLTSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(5763..6338)
                     /locus_tag="KRN00_002996"
     CDS             complement(5763..6338)
                     /locus_tag="KRN00_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828850.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
     gene            6653..6916
                     /locus_tag="KRN00_002997"
     CDS             6653..6916
                     /locus_tag="KRN00_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828851.1"
                     /translation="MIKNTKQITVEVNEILLQEMSKITNDENNILTDLINESIVNYIL
                     ENKKHNIENKDLEEVIKFYKKENTEKPKSAARAIAEAKTHTLY"
     gene            complement(7353..7730)
                     /locus_tag="KRN00_002998"
     CDS             complement(7353..7730)
                     /locus_tag="KRN00_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1828852.1"
                     /translation="MTITKIPPAELKVMKFIWSSDFTVASKDVIEAMEKLYNWKQTTT
                     LTLLSRLVNKQFLSARKIDRHTHYTVLIGEEEYLHFETKTFLDNMHGSSIESFMKSLF
                     KKGVNEEELNSVEKWVKDIKKDE"
     gene            8071..9183
                     /locus_tag="KRN00_002999"
     CDS             8071..9183
                     /locus_tag="KRN00_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBH1828853.1"
                     /translation="MNAFIRKRNKNYVVYLEFEDEKTGKRKQKNMGTFDKKREASKRL
                     NEVKESLYNDGFLVPSEITVSEFLLDFLNKYSENISLATYNNYVSICKNYINPSIGKY
                     KIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRAYRLKLIKENVMDSIEAPR
                     YKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRISEVLGLTWDNIDFEENTI
                     TVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEYKIKQNKNLLKSSIRNNNN
                     LLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHSHVTLLINSKVPIKVISER
                     VGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(9391..9867)
                     /locus_tag="KRN00_003000"
     CDS             complement(9391..9867)
                     /locus_tag="KRN00_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828854.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(10066..11691)
                     /locus_tag="KRN00_003001"
     CDS             complement(10066..11691)
                     /locus_tag="KRN00_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1828855.1"
                     /translation="MLQVIGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(12029..13048)
                     /locus_tag="KRN00_003002"
     CDS             complement(12029..13048)
                     /locus_tag="KRN00_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBH1828856.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(13045..13614)
                     /gene="mocA"
                     /locus_tag="KRN00_003003"
     CDS             complement(13045..13614)
                     /gene="mocA"
                     /locus_tag="KRN00_003003"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBH1828857.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCNGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
BASE COUNT         4769 a         2192 c         1429 g         5317 t
ORIGIN      
        1 atgttttctt caaattaatc agatgattta gtatatcttg aacctttcca gagtccttta
       61 aatatcctaa tgccccattt atttgtgatt ttaaatctat ttctacttcc atatccaaat
      121 caacatttcc tttttttata gatatatttt taagtgttat tgggtaaaga taactttttt
      181 ccaaagtaat cttatttcca ttaacctcaa atggaacttt tttattgtag ttacttaata
      241 ttttttctag cattttatca cttagtttaa attttccaat tttcacattc tcaagactta
      301 caactaagtt tccatccttt aaagtaggtc tcaattcaag ttcatattga ctatttacca
      361 aaccaaatac cttatatggt cctgctacct ttattttacc atttttcatt tcaacaaaat
      421 tattttcaag ttcattaatt ccatgcttct gcatcaatgt atatattaaa tttttaaact
      481 cttcctctga aacagatatt tttccaacca ttctaagtgg attttttact acctccatag
      541 aatttatata tgagcctttt gataaatatt cttcatctat gattttatta ttttgtgaac
      601 taacatcata tctttctttt ggtgtcaaga tatatacaac aattcctgca agtactaaaa
      661 caataacaat taaacttaac aaaatctttg caacctttcc cataatcgtc tcctttacaa
      721 atctgtcatc agatttaaaa taaatttaga taactaactt cacataatat tcttaacaat
      781 atacatacta taatacagtc ttttaaaaat taattcaacc aatctaatgt tttgtaaata
      841 aactgtaaaa acatgttttt agtataaaag ttaatatttt gcataatact cttaattaca
      901 cctttatttt tttctaatct tggattaaaa ttaatattat gcaatacagt gtagtgttct
      961 gtattataat caaattaaat aggaggtata gaatatgtca aatgaaacga actcatctaa
     1021 ctttataaag aatattatta taaacgactt agaaacagga aaacatgaca gtatcataac
     1081 tcgttttcca cctgagccaa acggatattt acatattggt catgcaaaaa gtatatgtct
     1141 taattttgga ttagctaagg agtttaatgg aaaagctaat ttaagatttg atgatacaaa
     1201 cccattaaaa gaggatgttg aatatgtaga gtccataaaa gaagatgtaa agtggttagg
     1261 atttgattgg aacgagttaa attttgcatc taactacttt gatgaaatgt ataagagagc
     1321 tttaatacta ataaaaaagg gtaaagctta tgtatgtgat ttgacacaag aggaaatgag
     1381 agaatatcgt ggtactctaa ctgaaccagg aaaagaaagt cctcatagaa acagaactat
     1441 tgaagaaaac cttgatttat ttgaaagaat gaaaaatggt gaatttaaag atggtgaaaa
     1501 aacattaaga gccaaaatag atatgtcttc tccaaatata aaccttagag acccaattat
     1561 atatagaata tctcattcaa cacaccataa tacaggagat aaatggtgca tatatcctat
     1621 gtatgctttt gctcatccaa ttgaagatgc aattgaagga ataactcact ctatatgtac
     1681 tttagagttt gaagaccaaa gacctcttta tgattggttt gttaaagaat gtgagatgga
     1741 aaatatacct agacaaatag aatttgctag acttaatata aataatactg tcatgagtaa
     1801 aaggaaatta aaacaacttg tagatgaggg tattgttgat ggttgggatg accctcgtgt
     1861 tcctacaata tccggaatca gacgtaaggg atatactgca gaagcattgc gcaatttctg
     1921 tagtgaaata ggggtatcaa aagttaactc tacggtagat agtcaaatgc ttgattattt
     1981 cctaagagaa aacttacaac caaaggctcc tcttactatg ggagttttaa gacctttaaa
     2041 acttattata actaattacc cagaagataa gattgagatg cttgaaatag agaataatgc
     2101 taaagatgaa tctcaaggaa agagattagt tcctttctct agagaattgt atatagaaca
     2161 agatgatttt atggaagaac ctgttaagaa atattttaga tttttcccag gaaatgaagt
     2221 ccgtttaaaa ggtgcttatt ttgtaaaatg tactgatgta attaaggatg aaaatggaaa
     2281 tgtagttgaa atacatggta cttatgaccc tgaaactaag agtggctctg gctttacagg
     2341 acgtaaggta aaatctacaa tacattgggt tgatgctaaa tcagctatac catgtgaatt
     2401 tagattattt gaaccattaa ttcttgatga tatacctgaa aatgaaggta aacatttctt
     2461 agaacaaata aatcctaatt cattggaaat attacaaggt tttgttgaac ctacacagat
     2521 aaaagatgct aaaccttttg ataaattcca atttgttaga aatggattct ttagtataga
     2581 taataaatat acaactgatg aaaaatttgt atttaataga atagttcctc taaaaagttc
     2641 ttttaaacca ggtaaataat cttacaatca aaaaatgaag acttaaaata taaattactt
     2701 ctactataaa taaacttagt tagaagtaat tttttatttg agtcttcatc atttacttta
     2761 aatgattaac ttttttcact acagattccc atgacttcta ttccatcttt tatgcattct
     2821 atgttaagag gaaaatctgg tcctttttct ccgtcaatat ctgttataag tgaatcttca
     2881 cattctatat gcaccttttt agttttaaag tatagtattt catttccatt atattgatct
     2941 aaataatcac ctctaagcac acttatcaaa actggtattg attttggtat tggcattcct
     3001 ttaaaaataa ttacatccaa atatccatca tctatttcag ccttatatgc tagatttata
     3061 tttcctgctg ttttgccatt aaaaatcaac ataagataca tatctccatc ataatacatt
     3121 tcctcagaag atacttttat cttaaatttc ctcatataca atgcttcttc tattcccttt
     3181 atataataag aaattcttcc aaatgaattt tttaagtctg tgtttatcct ttgtgataca
     3241 tccgtaaaca taccagcact tgcaacattt ataaagtact tattattgac tttccctatg
     3301 tctattttct ttggttttga atttatgatt tcatttatag cttcttttat atcaaatgaa
     3361 atttgaagag catttgaaaa atcatttgca gttcctgtag gcaaaattcc aattggaatt
     3421 tttatgtcta attctttcat tgcatttact actaaatcta cagtaccatc accaccagct
     3481 atcaatatgt gttcataaga actatcaact tccttaaatg cattctttac aggttcttta
     3541 atagttaatc tatagggtat caataaataa tttttttctt gatataattc tataatagtg
     3601 tctaaatttg ataatatctt tttttcacct gaattaggat tgtatataag ttttactttt
     3661 ttcattattt ctccttactc attttattct tttagtatcc aaaatcttca tttaaaaaaa
     3721 tcacatgtat tctttctggt gttaattgtc tttttataag tgtataacta cagcatattc
     3781 ttcctggact tgaacagtct atacatatac cagtagtctt acatccagta tttgtactta
     3841 atcttttaca attggctgga gcagctattg tttttgttct ttttatagct tcatctacat
     3901 ctttaactat tttatttact cctgctataa ctattacttt atcaggtcca tatatcatag
     3961 cagcaactct attcccattc ccatctaaat tgtaaagttc tccatcctct gttatcgcat
     4021 tagtacttgt aaaataagca tctgcagaaa atgactttct atatatttct ttcatttctt
     4081 ctggtttgat atcttttgca tatctatcaa gaaaattata tttttctctt ataaaatcaa
     4141 tcactcctgt ttcaaataag gtcatagaac ctccacatcc tactagagaa cctgctttaa
     4201 ctatttcttc aattttttta agaagctctt ctttgttact tactaaatac cctttcatat
     4261 tattgttttc caaagatttt attgtttttt ctattctttt ttcattaagc caatttaaat
     4321 tttgatccat tttaacttcc cccttatttt taatatgcac ttaattattt ataaacttta
     4381 ttttctttat aagtttattt tagtacatct aaaaaaaaat acaatataaa acttaaatag
     4441 ttttacataa ttttttccaa aataacttac tcaatcaaaa aaggaaagta gatgtactat
     4501 tctactttcc ctatattgta tgtagtattt attgcctaaa atctatatat taattatatg
     4561 tttcatatta tataatatca cagttaatta aaatgtaata ctatcttctt tttaaacata
     4621 taaattgtat tattaaattt aatatatcca acttcaataa atcttattaa tttgatgaag
     4681 aagatgctat agctgcactt gttgctgcca ttacacatgc aatttgaata gcaacaacaa
     4741 tatttaaaaa tatattatta gttatagagc ctatattatt ctcatttcgt atcaaatctg
     4801 cataaattga agctacaata gcagaactaa tcattactct attacttttt cctaaagacc
     4861 aatttccaaa gcctttttct tctttaagtt tatttgaaac attttttatc tcttctatta
     4921 tttcatcttc tctataatct aataatgaaa ttgctcctat tattggatat ccataataat
     4981 tcattttaca atcattttct ttaaatgctt ttttaagttc aatagtcttt ttacatttaa
     5041 gcatagttct atcatcacta aataaaagaa tttgggataa tgcttgtaaa tcatttcctt
     5101 tataaaaacc attttcattt agaaattcat aacatttttc tatgtattct aaatcttcat
     5161 ctaaattttt tgaatgaatt gcaataagtg ctatattaca atagtcatca ctagaagtta
     5221 gaaatggatg ttttttcctc atgtaatcat atattatttt catttttgat atacatgtaa
     5281 gataatccat tttctctcta ttttcataaa ctattgatgc tgtaagtggt aaatatgtat
     5341 cgccccaaaa cttttcactt ttaagttctt tgtatatatc taaaatcatc ttaaaactac
     5401 tttctggatt tgattcaaac gaaagtagtg ttgccatata aaacatatta tatcctctaa
     5461 aattagagaa taatccagta ttttttttaa taagctctat tcgttcttcc actaatctag
     5521 gacttattct cttgttctta agggtaaatg caagtgcaca actatgttgt atcaatccca
     5581 tttgccaaga acctttaact tcatttaatg ctttgtaatt ttctattaat aagtttactt
     5641 ttccatttat aaacgattgt tccatattgc cctcctagta atatatctca ttgtactaat
     5701 agttttatat ttattatata tatattaaat actacaatca atacatatta cttcaaagaa
     5761 catcattctt caacaataat gtagcctttt ttgtaatgtc ttcccatatt attgactcta
     5821 tcatagtact ctgattcact ttcattactc catttgggca caaatacatc tattgcatta
     5881 gaattactaa aatacttact agacccccta tccataacag tttttaattt tccatctaca
     5941 ataatcttag ttccaaaact taagtgattg tttgctacaa aaccatcttc taaatcatct
     6001 cctgtagcag ttatcgctcc atatccattt tcttgattaa gacttgtgta ataactaact
     6061 tcaaaagtta taggtactaa cttctttatt ttaataccta actgattttg tagtttctcc
     6121 ttttgtactt tcaacttata ctcatcacta tttttataat cttccatacc ttgattatac
     6181 ttggaattaa agcttttacc tgactttact atagtatcta tatttactat agattcttta
     6241 caatgatctg catctatttt tgtttctcca tttaccaata atggagttaa acatacacta
     6301 catacaacac atgtaatcaa tgcttcttta agcttcataa attcccccct tattattttg
     6361 atatattagc atatttaata ttatatgtct acatttagat ttaaatacca cacccatttg
     6421 ctttaagaag ttgtcttata tttaattcac cttaaacact tataaatcct ctatcttaga
     6481 atcatataga ataaagcttt tatctttaaa tattttttat taatctttta aaatctaaac
     6541 cactttatct aattttctct tttttagaat ttaagaatta aaattctata attttaaaac
     6601 atattgaatt tatttttttg agatgatata attttcttaa gaggtggttg atatgataaa
     6661 aaatacaaaa caaattacag tagaagttaa tgaaatttta ttacaagaaa tgtctaagat
     6721 aactaatgac gaaaataata ttttgacaga tttgataaat gaatcaattg taaattatat
     6781 tcttgaaaac aaaaaacata atattgaaaa taaagattta gaagaagtga ttaaatttta
     6841 caaaaaagaa aatactgaaa aacctaaaag tgcagcaaga gctatagctg aagcaaaaac
     6901 tcatactctg tattaatcaa ataaaaaagt tcctaaaaac taggaacttt tttatattaa
     6961 taattattaa tatatctcaa tatttatctc aaatctatca atataagcat gtttaataca
     7021 atctattgta tacttatctt accctagaaa taatcaaaac aaaaataaaa ttatgccctt
     7081 tatatctaaa acaattaatt tacatgatta atatacaaaa attctgactt ttaaattcgt
     7141 atacaatatc aaactaaaat aatattaatg acaaacccaa tataaattaa attcaaacag
     7201 gtttgatttt acatcaaact tattgtatta atattaaata acaagacaaa aatatttata
     7261 aaaatcacaa attttacata aaactttata tttgattcat ttaactaatt attgtaaaaa
     7321 ctatttattt tatgataatt aactacacca aattattcat cttttttaat atccttaacc
     7381 catttttcaa cagagttcaa ttcttcttca tttaccccct ttttgaacaa ggatttcata
     7441 aaactctcaa tagaacttcc atgcatatta tctaaaaaag tttttgtttc aaaatgtaaa
     7501 tactcttctt ctccaataag aactgtataa tgtgtatgtc tatcaatttt tcttgcactt
     7561 aagaattgct tatttactaa tcttgataaa agtgttagtg ttgtagtttg cttccaatta
     7621 tatagttttt ccatagcttc aatgacatct tttgatgcta ctgtaaaatc tgaactccaa
     7681 ataaatttca tgacttttaa ttctgctggt ggtatcttag taatagtcat atgattttac
     7741 actcctctca aacttctaca taattaaata ctatattaat agacttttcg agtcaaaggt
     7801 tttatttaaa atatctcatc caaatttatt aatacaaaaa atttatattt ttattcaaaa
     7861 ttaaacacac aatctattaa tataaagata aatatctatt ctataagtat aacagattat
     7921 caaattaaaa ttctaatatt tgacataata tatacatttt ttaaataaat atatacaatg
     7981 tattaaaatg tatgcaactc tatttcaaaa ttattttgtg atatatatat gttataataa
     8041 atgtataaaa ttttgattgg tgggttacat atgaatgcat ttattagaaa aagaaataaa
     8101 aactatgttg tttacctgga atttgaagat gaaaagacag gtaaaagaaa acaaaaaaat
     8161 atgggtactt ttgataaaaa aagggaagca agtaaaagac taaatgaggt aaaagaaagc
     8221 ttatataatg atggtttttt agtaccaagc gaaattacag tgtcagaatt tctattagat
     8281 tttctaaata aatatagtga aaatatatct ttagctacat ataataatta tgttagtatt
     8341 tgtaagaatt acattaatcc atctattgga aaatataaaa tacaagactt acatccggtt
     8401 cacatacaaa actacataga taaactatct tataaactaa atcctcaatc aattaagatt
     8461 catataaata tattgaaact tgcaataaaa agagcttata gactcaaatt aataaaagaa
     8521 aatgttatgg atagtataga ggctccaaga tataaaaaat ttaaaaatga gatttatgat
     8581 agagaacaaa tgataaaatt attagattta gcaaaaaata cagaaatgga attacctatt
     8641 aatttggcta ttggattagg tcttagaatt tcagaagttt taggtctaac ttgggataat
     8701 attgattttg aagaaaatac aataacagta aataagataa cttcccgaat taatggttct
     8761 gttattctca aagagccaaa gacagaaagc tctgttagaa aaatatcttc tcccaaagaa
     8821 ttaatgtctt tattaaaaga atataaaata aaacagaata aaaatttatt aaaatcttcc
     8881 attagaaata ataataattt gttgtttttc aataagaaat gtgaacctat tgctgaagat
     8941 gttatgagta aaaaatttaa aagattttta gaaaagaatg aattacctca tattagattc
     9001 catgatttaa gacactcaca tgttacttta cttataaatt ctaaagtacc tataaaggtt
     9061 atatccgaga gagtaggaca ctcaaatata agtactactc taagcgttta ttctcatgta
     9121 cttaaagaaa tggataaaga ggcttctgac aaaatttctg aaagtttatt taatgctaat
     9181 taatattaat ttatcttagc tttaaattag cttagcttat tgagatagat tcattaatat
     9241 taaatgtatc tatctcaaat taataactac ttaaataatc tgttttattt taatttatcg
     9301 cctcagttat tatacttttt tacgaaaaat tatactttac aataaaaaag atattccctt
     9361 atagaaaata tctttttaaa tactatatta ttatatactt gctaacattg gaatatctaa
     9421 catcttcttc attacatcat ctactttttt tgctttatat tcattgtatc caattaaata
     9481 tcctttttca tatgaacttt ttaaaatctc tttttcatat aaattatcag atttggcttc
     9541 tgtgacactt aaattataaa gccctttaca cccatcttca taacctttat tatacccttt
     9601 ttctgcaaaa tagtttttat gatttttttc gttatgtact gaagatattg ttactccaga
     9661 attttctttt gtactagcat aaggacaaaa acctttattg tgttgatgtg ctgaatgtcc
     9721 tccacaataa taacgtgtta actctgattt atttttatta tgatgacctc ctgatgaatt
     9781 atgccctcct gagtgagcat atgaaaaatt ccctacacta atcatagcta aactcaatac
     9841 tacagctact aaccttttct taaccataat ctattccccc caaaatgtta tatattttta
     9901 ttatatcatc tactatatta tatttaaatt cttaatatac aaaatattac tctattctgc
     9961 taataaacat gtttaaacaa cataaaaaac ctcctaatat ttgattaaaa atttacacac
    10021 tcatgcatag catgtctcaa atattaaaag gttttatact aataattatt tatcttttcc
    10081 atacatttta gctaattggt cttgtatctc tttactttct aaatactcat caaagtccat
    10141 ttttctatcc attattccat ttggagttat ctctataatt ctatttgcta tagtagatat
    10201 aaattcatgg tcatgagaag taaataaaag cactcctggg aacttttcaa gtcctttatt
    10261 tacagaagtt atactttcta ggtctaagtg gttagtaggg tcatctaata caagtacatt
    10321 tgcatttgaa agcattagct tactaagcat acatctaacc ttttctcctc cagatataac
    10381 ttgagcttct tttaatgctt cttcacctga gaataacatt ctacctaaaa atcctcttat
    10441 aaaactttca cttttttctt cagagaactg tctaagccag tcaaccaaag aatattctac
    10501 tccgtcaaaa aacttattat gattttttgg aagataatct tgagaagtag ttactcccca
    10561 tttatactct ccactgtctg gttcaagttc tcccataact atgttgaaaa gtgcagtagt
    10621 agctatttca tctcccataa atactacttt atcatctcta tccaatctaa atgacacatt
    10681 atcaagaacc ttaaccccat ctatagtttt agttaaattg tgtacttcta aaacttcatt
    10741 cccaatttct cttgcaggtg taaatcctac atatggatat cttcttcttg atggttgtat
    10801 atcttcaact tctaatttct ctaactgttt ctttcttgat gttgcttgtt tagcctttga
    10861 agcattagaa ctaaatctag ctataaattc ctttaattga gctatctttt cttcagtctt
    10921 tttattttgg tccttagcca gttgtaaagc caattgactt gactcatacc agaaatcata
    10981 gtttccaacg tacatttgta ttttaccaaa atctacgtca actatattag tacatatttg
    11041 atttaggaaa tgtctatcat gtgatactat tataactata gattcttcta aatccattat
    11101 aaaattattt aaccagttta ttgatttaaa atctaagtgg tttgtaggtt cgtccattaa
    11161 tagtatttca ggcttaccaa aaagtgattg tgctaacaat accttaacct tttccccacc
    11221 aactagttcc ttcatttgtt tgtaatgcat atctttcgtt ataccaagac ccataagtat
    11281 tttctcagca ttagtttctg catcccatcc gtcaagctct gcaaactcac cttcaagttc
    11341 ggcagctttt atcccatctt cttcattaaa gtcttccttc atatacaatg catctttttc
    11401 tttcattatg ttccaaagtc tctcatgacc tcttataaca acatttaaaa cagtttcttc
    11461 ttcatattca aagtggtcct gttttaaaac tgacattctt tctttatcag ttatagatat
    11521 actacctgta ttaggctcta tttctcctga taatattttt aaaaaagtag attttcccgc
    11581 accattagct cctattattc catagcaatt acctttagtg aattttaagt taacatcttt
    11641 aaatagttcc ttatcaccaa atctaagtcc aacacctata acttgtaaca ttaatatatt
    11701 ttcctttctt tttgctcata atttatttta tcataaaact ttgataacat ttttattata
    11761 tattatcacg taaatagtat attttttata ctaaatttgt gaaatattta ttaaaataat
    11821 actaaaaatt gtaaatttat aaaaattaac aatctcttat attatactta taaagaaatc
    11881 aaattgcaac tttattcatt cttttacaca ttgaaaataa gttattataa tttctaaata
    11941 aatatgcttt ttttaaaaca tcattctagc tgttttgttt catatttaaa aagagtactt
    12001 aatttgtaaa tactcttttt taataacttt atattttagc aaaattacat gcaggataag
    12061 tacatacatc acagttcata caaaggccac catgaccata tctagctata tcatacttat
    12121 caagcttttc atcaattaaa accctagata aaactatatc aaatactgta gttttgtgat
    12181 acattgcgca tcctggtata cccataattg gaacttctcc ataataagca agtaaaaaca
    12241 tagctcctgg taatattggt gaaccatatg tcactaaatc agctccagtt tcttttatag
    12301 ctgttggtgt aacatcatct ggatctacac tcatcccacc agtacaacag ataagttctg
    12361 ctccttgact tataaattct tttattgcac tctttataat ctctttatca tctgggcata
    12421 tagtctgtcc tataacttca caaccaaagc cttttacttt ttcttctatt acgggtccaa
    12481 atttatcaac aattctgcta taaaacactt catttcctgt agtaacaatt cctactttct
    12541 taggtttaaa aggtactaca tttactattt ttctattacc aactactttt tttgcatctt
    12601 ctaatttttt ctcatctata accaaaggta tcactcttgt tccagctact tttaaacctt
    12661 tatttactat aaaattatta tgaagagtag ccatcattat ttctccaaca caattcaaat
    12721 caaaaagtgc atcaacatct atctttaata gaccatcaca tgctgctata aaatctattt
    12781 tcccttcttt tatttcacta aaatctaaat tttctccagc agttagttct tttaaaaaca
    12841 atgcgccttc attttcatga accattcctt ctgacttttc ccatacatac aaattatctt
    12901 taccaagaga taataacact ggaatatctt cttcttttac tatgtggccc tttttaaatt
    12961 ttcttccttt aaattctcca ggtattattt gagttatgtc gtgacataaa acttgtccaa
    13021 cagcatctat agtttttatt agcttcataa tttaccccca attctctcat aatccatttt
    13081 tgtatcgata tcaaataaca tttctttagg aacttctaca tactttattt ttgatgaatt
    13141 ttttaaaatg gttttacctt tttcatcttc tttaagtgcc aacaattctt ctttcttact
    13201 atatgggaat atgactggat ttccacacat atctttgtat cttggaatta ctataaaatc
    13261 tctatctaat ttaaaagtat ttataatttt atctatatat aagttatcaa taaatggctg
    13321 gtctcctaca aagaacatat aaccattaca ttttgagcta tttaaaactc ctaattttat
    13381 agattcactt tgacctatat ttgcattttt attatctata tattcaaaac catatttatt
    13441 acacaataac aaaacctctt catattgact tactactaca acttgatgaa aatcaatctt
    13501 gctaacttct ctaaatacat gttctattat agaacagcct ttataattta ataaaagttt
    13561 atttgctccc attcttctgg caaagcctga tgccattatc actgcattta tcatatatat
    13621 catccttggt atttataata tattgatagt tctatgattt ttataatatc tctattgata
    13681 ttatctatat atataatatc atataaa
//
LOCUS       DAEQAF010000097        13699 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.100, whole genome shotgun sequence.
ACCESSION   DAEQAF010000097 DAEQAF010000000
VERSION     DAEQAF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13699
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.100"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(225..1892)
                     /locus_tag="KRN00_003004"
     CDS             complement(225..1892)
                     /locus_tag="KRN00_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBH1828858.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(1966..2721)
                     /locus_tag="KRN00_003005"
     CDS             complement(1966..2721)
                     /locus_tag="KRN00_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBH1828859.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EVLTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(2731..3267)
                     /gene="lepB"
                     /locus_tag="KRN00_003006"
     CDS             complement(2731..3267)
                     /gene="lepB"
                     /locus_tag="KRN00_003006"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1828860.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(3433..3969)
                     /gene="lepB"
                     /locus_tag="KRN00_003007"
     CDS             complement(3433..3969)
                     /gene="lepB"
                     /locus_tag="KRN00_003007"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBH1828861.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(4069..5379)
                     /locus_tag="KRN00_003008"
     CDS             complement(4069..5379)
                     /locus_tag="KRN00_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBH1828862.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(5458..6174)
                     /locus_tag="KRN00_003009"
     CDS             complement(5458..6174)
                     /locus_tag="KRN00_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBH1828863.1"
                     /translation="MKLDLFLLAIVPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            6419..7690
                     /gene="sleC"
                     /locus_tag="KRN00_003010"
     CDS             6419..7690
                     /gene="sleC"
                     /locus_tag="KRN00_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBH1828864.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTSLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(8198..8854)
                     /locus_tag="KRN00_003011"
     CDS             complement(8198..8854)
                     /locus_tag="KRN00_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828865.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGARILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(10127..10537)
                     /locus_tag="KRN00_003012"
     CDS             complement(10127..10537)
                     /locus_tag="KRN00_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828866.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(10753..12135)
                     /locus_tag="KRN00_003013"
     CDS             complement(10753..12135)
                     /locus_tag="KRN00_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBH1828867.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSSIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIEQSGYNDNRFVISRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(12146..12505)
                     /locus_tag="KRN00_003014"
     CDS             complement(12146..12505)
                     /locus_tag="KRN00_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1828868.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(12710..13489)
                     /locus_tag="KRN00_003015"
     CDS             complement(12710..13489)
                     /locus_tag="KRN00_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBH1828869.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
BASE COUNT         4666 a         2478 c         1332 g         5223 t
ORIGIN      
        1 aaaataatca cataaactaa caaaatatta aacaaaaaag taaaatttaa aataaaaagc
       61 ttgcttcata caaaagtata aaacaagcct ttttatatat caactcaaac tttaaaatct
      121 gtatcaattt aattctccac tttacactta atatacttaa cataaaccaa taacactact
      181 tgctatgcca tttaatcttc ataaaacaat ctataataca cacattaatc aactatttta
      241 cttcctccaa taaattccct aagaattgaa atacctggta tgtcagaagt atcgtccaat
      301 tcaacaaaat actgcaaaaa ctttagtaat ctagtagctt caatatgtgc aggattatct
      361 tcctttatct cttccaacaa aggtttcgca aatcgtttta aaactgccaa ttcatataca
      421 caagcagagt taaatatagc atctgcctcc tcttggtacg ggaatatatt cttcttttct
      481 cctcttctaa ctgatgccca ttgtaaaata gtattatcag cactatatcc tctaaaatta
      541 tagtctctaa caattcttct tatcattctc aaatcagcag tagggattcg attatggtca
      601 tccaaattta tttgagtaag ggcacttatg tatatcttaa atttatcttc atctggtata
      661 gatgatgtta aaataggatt tagcccatgt ataccttcta atataattgg ctgatttgaa
      721 tctatcttta tctttttacc agtgtattct ctcttacctt ctttaaaatt gaatcttata
      781 tcatcaattt cttcaccagc taaaagtttc tttaagtcta agttaaactt ctctaaatct
      841 attgcataaa ttgattcaaa atcataattt ccatattcat ctaaaggagt atgttttcta
      901 tctataaaat aatcatctaa agaaattgaa ataggattta aattatttac tctaagatgt
      961 attgataatc tgtgagcaaa acttgttttt ccagatgaag atggagctgc tattaaaact
     1021 actctcttat tgccatcctt tatcatatcc gctatttggg ataacttctt ttcatgcaat
     1081 gcttcaaatg tccttattat atctccatat tcattgtttt ctattatttt attaagagat
     1141 actaccttgt caattcccat aagtcttgac cattcttctg cttcataata tacacttgat
     1201 agcttaggtt gaggtacaaa tttcatagga agagtcttat cttcttcact aggtcctaaa
     1261 attataacgc ctccattata aagcttaata tcaaatgatt ttatataacc agttgatggc
     1321 aacatataac cataaaaatg gtctatatag tttctacact tatatacttt agcactatca
     1381 tactctttgt atttcaaaag ctctgccttt tcatacattt cattattttc aaagatagaa
     1441 atagcttcat ttcttgtaac ttcaattttt tctataacat aatcgttgtt tactatctct
     1501 ttcatcttgt tttttatatt ttcaacatct gcttctttaa gctttctatc tatatgaact
     1561 tcacaatata gcccatctga tagtgaatgt tctattgtaa ctctgctatc ccaaaagatt
     1621 tctctacatg ccattacaaa tataaatgac atgactctaa agtaaactct ctctccatct
     1681 tcattagtag tatctaaaaa atttatctca caatccttct taactctaca atttagctct
     1741 tttagtttat tgtctacaac tgcaagtgtt atataaccct tatgctcatc acaaaattct
     1801 tttgctatat ctcccaatct aattccaggg gaattttctt ctaatgaata ttccttatct
     1861 tttccttcta tttttaagtt tatttttttc acttcaacat ctccttcctt ttgatgaata
     1921 taaattttaa ttaatgaggc atatcaacaa gataaagaga ggtatttaac cctctcctac
     1981 aatattattc aatttactta tagtatcttc aatgtcttcg taatttattt ctaatactaa
     2041 atattctgca tctaatgtta agacctcttt aatcccctct tcagataaaa ttcctcttcc
     2101 tataccaaca tgtgtatcat tgataccatc attatcactt aagtgtatca gtcttatttt
     2161 atcctttaag ttctttacat aagcatcctc atcaattaaa cagtgtccag tatcgtaaca
     2221 aaaacaaatc ttagaatttt taatcctctt aaatatatat tcaaaatcat aagatatatt
     2281 tccaatattt gaaaaatccc caccttttga ataagtattc tctatacata catatgaatt
     2341 tgtatttaat ttatctaaaa aatccacact atttcctaaa tatttgtctc tattctttct
     2401 aactctattt gtcataacat atcccaaatg aaggttaaaa taccttaaat caaatccttt
     2461 tagttcaaat tctatcttct caataaaatt tatccatgaa tttcgtatat actctatgtt
     2521 ttcgcaagta tttaattcca taggcaagtg tatccctata gataatccta acttagaaat
     2581 tctctcttta tatttacata actcactaca ttcagatata ttgtcaattc caatctctaa
     2641 atgagttatt tgctttatac tctcacaaat gtttaaagcc tcctcaatat taaacaataa
     2701 ggacgctata ccaactgcca tacaaatcac ctactcaaaa atacctatat ctgtaaaagg
     2761 aaatactctt aaaataactt ttcctttaat attttcttca tctactaatc ccacttcttt
     2821 atatctactg tctaaactaa cttctctatt gtctcccatc gcaaatactt ttcccttagg
     2881 aatcaccata tcaatatcgc cttcagtata attatcatgt atatatgaaa cttcatttaa
     2941 taacttacca tttatataaa ccttagaatc cttaattttt agatggtcac caggaacacc
     3001 tataaccctt tttacaagct cttttttcct tccattctct tgtaataaat cagtcttaaa
     3061 tatcattata tctccacatt ttggttctga taacttatat gtcatcctgt ttgctaccaa
     3121 ataatcatgt gatttaagtg ttgggtacat tgattctcca tttactaatg ttggttttat
     3181 aaaacgagtt ataataaatg caaaaaaaag tgcagtaata attattttta tccactctac
     3241 aatctcttct ttaatagttt cattcattca caaattctcc tttatagtta tattatcttt
     3301 attgataatg tctcttaaac actatctttt agataagtct actaaataag gttttgtctt
     3361 ttttatatag acaactattg tgtatggtct ggtgatttca gctaatcagc gattgctcca
     3421 aattttatat gtttagtcaa tagttcctat cttagaaaat ggatacaatc tgactagaac
     3481 ctttcctaaa atggtatgct cgtcgaccaa tccaacctca tcgtatctac tatctaaact
     3541 tttttctcta ttatctccca ttgcaaataa ttttccttct ggaactacga tatcaatatc
     3601 tccatcagta cgattattat gtatatagga agtctcatct aacaacttat catttacata
     3661 taccttggag tcttgtattt ttacatggtc accaggaacc ccgataactc tttttactaa
     3721 atcttttttc tttccatttt cctctgttaa gtcggttttg aatactatta tatctttgta
     3781 ttttggctct cctaccttgt acgcaattct gttaactatc aaataatcac gttcaactaa
     3841 tgtaggatac attgattctc ctttgactat tgttggcact ataaaacgag ttattgcaaa
     3901 tgccaaaaca agagctatga caatcacttt tatccattct acaacttctt ttttaactgc
     3961 ttcacccact aaaatcgtct cctctgtgtt aaatattaag tcaatctaca gcaaaataat
     4021 ctaccataaa cctacaatat aaatattata cttctttttt ctaatagttt aaaatacttt
     4081 tctaagacct ttaggataat gattcttaat tacaccagaa gattcttttc cccaacctaa
     4141 aggtattcct tcaaccgaaa ccaaaaccca tcctctacta tcattagaat ttacaacatc
     4201 cccttttaaa tatttaagaa ttgattcact ctgtacactg aagttttcaa cattttttac
     4261 atcttcaact tttaagtaat gagatagtgc atgagaaggc tcaaatctat tcttctttaa
     4321 aacccctaaa tgcaaaccat atctcaatac ttttagtttt ttcgtatctg gatatatttc
     4381 aggaagtagg tacaaatttt ctcctcttaa ataaaattta ttttttttat tactataaaa
     4441 atcaaccttt aaaaatttct tttcaaactc cctataatcc tttatttctt tatctaaatt
     4501 ttttattttt aattctttga cattacattc ttcttcttct aattttttta ttttggcaac
     4561 aaaatgacct tctcccttta tcttatgagg ccataatctt tccatttcaa taagttctgc
     4621 atgtggatat tcactgataa actcatttat aacatgctca ttttcctccc ttgaaaaagt
     4681 acaagttgag taaattaaaa tgccatcctt ctttaacatt ttatatccat ctcttataat
     4741 ctctttttgg atggattgac attctactac ctttgcataa ctccaatctg atatggcaac
     4801 ctcatccttc ctaaacatac cttgcccaga acaaggtgca tctataataa ccttatcaaa
     4861 atacccatta aacgtctttc ttaagctatt agaatcggtg tttgttataa tacaatttct
     4921 cgctccaaat cgctctaaat tttcccctag agccttaatt ctactagcat taatttcatt
     4981 agaaaccaat aaacctgtat cgtttagctt agatagtata tatgtagatt ttccaccagg
     5041 agcagcacac atatcgagaa ctttttcacc ctctttaata tctgcctttg gtattacact
     5101 cattgcagaa ggctcttgca aatagtatgc tccagcctca tgcagtggat ttctaccagg
     5161 tctgtcaatt ttatcatcat aataaaaacc ttcttctgcc catggtattt gattcaaatc
     5221 aaacaactcc aaatcaaata attttttctt gtcaattttt aaagtattta ttctaagccc
     5281 agtagtctta ctttcctcat aactttttat aaaatcatca tattcatctt ttagtatttc
     5341 ttcaatatct tctaaaaatt cctttggtaa ttctgtcaaa tctataatcc cccttcaatc
     5401 tgctttactt gtgtgtcatt tattatactt taattattta tgtctttcct ttaaatttta
     5461 tttcttcttc tttttcctaa gattaccgaa aaacactttt ttagagtgat tcatatattt
     5521 ctcaagttta tcaagattta tcttccacaa aattattaca taaactataa gtaatataat
     5581 agcccatcta tattctatca tcaatatgaa atcaaaaact ccatgtaata aaattggaat
     5641 taacactgcc ataaacaaat actcacgtct tttattttta tttccctcaa atttatactt
     5701 agaaatatag tagcccatag taattgcaaa cattacatga gctggtatag agataactgc
     5761 cctattaata ccaacttgca gtgctagatt tctactttca gaaaaaatat aaaccatatt
     5821 ttcaattgtt gcaaatccta aagctaaaaa tacagagtaa ataataccat ctaacttttc
     5881 agtaaagtgt ttttctttaa ttagggcagg aatcagtatc agagctttta caccttcttc
     5941 tacaagtcct gcaactacaa atgatacata tattagttct gaataccctt caaatacatt
     6001 aaacttcatc agtaaatttt ctaaaagtat aattataaca cttagaaaag cacctattaa
     6061 aaaaaattta attagatgga ttaggggttc tctacaatat ctatctttag accttatcca
     6121 aaacatccct atcaatatag gaactattgc taataaaaat aaatctagct tcatagatta
     6181 ttttcctttc aaaatttttg atttatttat gatttatatc atctacttat ttttaactta
     6241 ttcgtgtttt aaatacatac taaaatatac attaaattat tttaaattat ttaaatacaa
     6301 atatactcaa atactcaaaa aaatttaaat ttatatctat attatttaac aaatttcaag
     6361 ctatattcat atcttgaaat ataagggaac taaattcatt taaagaaagg gtgatttgat
     6421 gcaagatggt ttcttaacag taagcataat tgatgctact aacaatagac ctattcaaaa
     6481 tgcagtagta aacatatatt caatgtctaa tggtagccaa agctcatcaa ctttatacca
     6541 aaacctaaga agtaatgaat ctggtcaagt gactagttta gtattaccag caccagatgt
     6601 agattactct ctacaaccat ctgatgttag accttatagc cagtatatag tggaagccat
     6661 agcagatgga tatgagacag ttgtcataga aggaacacag ttgttagcta caattgaagc
     6721 aagacaagga gttcccatgt ctcctagaac aagaagtaag cgttctttct caagacaaag
     6781 tgagttgatt tttgatatag gagaacatac tctatatggt acttatcctc ctaagattcc
     6841 agaaagtaac ttaaaaccat taccacctcc tactggtttc gttgtattag ataaccctgt
     6901 agtgcctgaa tttatagtag ttcatgatgg tttgccagaa gattcatcag ctccaaacta
     6961 ttggattcca tttaaagagt acattaaaaa catagcgtca tctgaaatat attcaacttg
     7021 gcctgaacag acaatctatg caaatgtaat agctataata tcatttactt taaatagagt
     7081 ctttactgaa tggtatagaa ataaaggata taactttaca ataacttcaa caacagcata
     7141 cgaccataag tttataaata atagaaactt atttgaacca attaacgtag ttgtagatgc
     7201 tatttttaat acttttataa aaagacctcc tacatcaaga cagccactat tagcacaata
     7261 ttgtgatgga caaaaatccc aatgtcctga ccaaatgact caatggggca gtaaagactt
     7321 aggtgaccaa ggatatgact atgagagtat actaagatat ttctatggag atgaaatagt
     7381 atttgaaaga gcacctatag taagtggtgt accagtgtca ttccctggta ctacactaca
     7441 agttggttct tctggacagt atgttagaac catacaaaat cagttaaatg ctatatctaa
     7501 ttcttatcca gctgtaccaa aagttataga ggatggtatc tatggaacag atacagaaaa
     7561 cgctgttaag atattccaag gaatctttgg tttacctcaa agcggagtag tagattttaa
     7621 aacatggtat gaaatatcca gagtttatgt agctacaact agaatagctt ctttaaatcc
     7681 tttaatttaa agcttgattt agaacataaa ctcaaattat tgaataaaat tattaattta
     7741 aaataaaaat ggctgttatg aactaatata taccataagt attacttata agtattgtag
     7801 tcttaacagc cattttttag ttataacttg tttttttaga atcttaaaac tttaaatggg
     7861 ggattttaag cttcttaaaa acagtgctta gcaacttaga tttctttaaa atattatatt
     7921 tatttttaag tttaataaaa tgctattcta acgaaaaacc tactttttat ttaaaatctc
     7981 acttattatt taaaacacta tctatcactt agagtattac tccttattat ttaaaacact
     8041 atctatcact tagaatatta cttcttatta tttaaaacac tatccatcac ttagaatatt
     8101 acttcttata taaattatta tttattataa atacaaataa tattaattta aaaagttatt
     8161 cctaatttaa ataatactat tatcttcatc agtgaatcta aactgcaact ttagacttat
     8221 tagctaaagc caatattaga cctaaagcta tagatgcaaa tgcagaagca attactctat
     8281 actcagcagg gaataaaaat acaattgtat gacatggtat ccagaaaaat ggtatagttt
     8341 ttaaaacact aaaaccaagg taagcattcc agtccacaat atttaccaca tctttaagtt
     8401 ttaccttaat cccctttcca acctcatatt ttttatctat aaaacagtcc ataaccttat
     8461 ggaataaaaa tacagttggt gacattagta tattcatagt tgcactctta aatagagcat
     8521 ttgcaaaagc tattccctca aatggaagca taccatccac ttgtgcttga cctacacctg
     8581 atgagtagat tgacattcca tatgtggtaa ctacacctat tattccccaa actattgctc
     8641 tataaaatac tcctactggt attttccaat ccttatacaa aattctagca ccaagtaaat
     8701 ctcccattgt agctaataca gcaaacttta aaaaacctcc aatatatgga tgtgcacctg
     8761 ttgcttccat aaatacttct ctactacttg gtattgctaa gacagcaata atacaaataa
     8821 gaactccact ccatataaaa tcgccttttt tcatatttat aaatactatt taatatataa
     8881 atagttctcc tttctattaa agatttattt aatttacaat ctatctacaa ttatttatta
     8941 atcacttatt attagatatt cattttccat atttaaattt attctatccc tttatctatt
     9001 tattttctta ctactctatc caccattatc tatatattta ttttacgatt actctttcac
     9061 cctaaccctt taattatcta tttttttctg atattcttat ctaccatcat ccatatattt
     9121 attttacgat tactctttca ccccaaccct ttaattatct attttttctg atattcttat
     9181 ctaccattat ctatatattt attttacgat tactctttca ccctaaccct ttaactatct
     9241 attttttctt actattctta tccacatcat ccatatattt attttacgat tactctttca
     9301 ctctaaccct ttaactatct attttttctg atattcttat ccaccatcat ccatatattt
     9361 attttacaat tactctttta ccctaaccct ttaactatct atttttttct ggtattctta
     9421 tctactatta tctgtatatt tattttatga ttactctttt aacctacccc ctatacttta
     9481 tagtaatatg tttttaacct ttttcattat tcccaatatg ctttataact acaaatactc
     9541 tcccccctta aaaataataa taaaattaat caataaattt ataatcatat tattactcta
     9601 tgtattaagc aattactatg ccaataaact ttgatttttt taaacaaatc ttaaaaatcc
     9661 taaaatgcta attttcttta acttttaatg aatctaatag ataacattta attttcgtta
     9721 tatttttcag aatatttcta ttattatttt taagaaaaaa aaataatgtt aacatttctt
     9781 aacatacatt aaaaaatgtt aacattataa attgggttta atacttttac tttgactcga
     9841 tttactttta ttctacttct tactttattt ttaacttaga ctttattttt ttattactta
     9901 tttgagtctt atttatttta ttatcactcc atatgttcaa ttacatttgt ctaaattctt
     9961 tgatactttt attacataat tttaacaagc ttaagtgtta tttgggtagt gcagttgata
    10021 attatttaaa taatcatcaa ctgcatgttt atatcattac agtagcttaa tgtatttaat
    10081 catacttact taggattttg aaatatctta gagattatat ttaacattag tcaattgctg
    10141 cataattgta agcaattgaa atttgagacc catcttcatt ttctatagtg ataggcttca
    10201 taatttttaa tccttcagtt tttatctttt ctaattcttg ttccattttc ttaattgttt
    10261 cctcaaggtc tttttgactt acatctttga ctgcattagg gtctttagca tagtctttta
    10321 attcttgaat atgtttagca tactcttcat aagtataatg ctcaacacca tacttttcca
    10381 attcagtagg gtcagttatt cctgatttta ttagagattc aaatttaggt aaagcaatat
    10441 tagatgaatc atttccattt gcaaatactg ctccagttcc tcctagtacc attgcagata
    10501 ccatcattgc acttataagg gattttttta ttttcataac caatcttcct ttcttagaga
    10561 tttatttggg tagtgtagtt tgaaatgact attgcaatag ttatcaacca cacccttaga
    10621 ctatcacagt agtcatgttt atgtcaagcc tttttaaaaa acttttcaat aaaaaatact
    10681 atctcaaaac aaaattaatt attttgagat agtattttaa ttctaaatct tttatattac
    10741 taagatttat ggttactcta tccatgttct atattgttct ttattaactg ctaacaaatt
    10801 cccttttctt gatatgacaa agcgattatc attatagcca ctttgctcaa ttgaaacttc
    10861 tcctgaatca gtataaagta catccttact attactagat ttatttacat acgtttcttc
    10921 actattctca gaattagtta ctttgctcat agatgattct tcatgctctc taaattcaat
    10981 tacagatact tttgccgtac taaaatgagt ctctccatca cttttagctt tactaacaag
    11041 aatatcagat tctactttgg gagaatataa atcagttgat ttactactta ttgaaaatcc
    11101 aattttatca ctttgttcat tttttgttaa accaaaagat tcaacctcat taatctcttt
    11161 attttctgtt gcaaaaacaa gacctgtccc acaaactaat acagttgaaa ctaaaaaagt
    11221 aacataagtt gattttttaa atttcataat attaactatt ctcttttcta tttttgtctt
    11281 tccaaatcca ctacatattg tcattgaaaa tggattattc tcctctgcta gacttattag
    11341 tgtggttgca taatcagccc tatattcttc accaagtata ctcataacct tttcatcaca
    11401 actaaattct atgtctttat ttagtaaaaa aaacatcacc caaactaagg gattaaacca
    11461 atggacaaca agagctacaa gcataaataa ctttaacaga ttatcaaagc tattaatatg
    11521 aaccatttca tgagttaaaa caaagtctaa agtttgatta ttagcataat tcatttgctt
    11581 tggcaaaata attcgtggtt ttaaaatacc agatgtaagt ggtgtcctag taaattcaga
    11641 tatgcaaaca ataaatcttc taaaacggct attcttacac atccattttt taatgaactc
    11701 atgatttttt atatgaattg aagttttaaa aagattaatt attttaaaat atctaaagca
    11761 taaaagtatg ctaaacataa tagtaactat aaaagacaaa atgcccaaca tttccaacat
    11821 cataatattt tcaatactag acattatttc aaattcgtca gaattgtttt tacctgtaga
    11881 gtcactagct ttcttaagag tataattttc tgttgatgta ttacccaatt ccacatcaaa
    11941 agtcgattca attatactat aaatactaaa accagaattt aaacttactg gtattagaag
    12001 tttaaataaa acaatcaacc acaataatac aaataccttt ttaggtaatt ttttaaataa
    12061 acatgctctt ataaaaataa ctattaaaag taatactcca gaagtaaaac tcatttctaa
    12121 caatttaatg aacataaatc ttacctcact ttaatttttc aacaatttgt ttaagttttg
    12181 taatctcatc acttgaaaga ttttctttat taataaaagc tgaaagaaat ttttctgaag
    12241 accctccaaa cattttatta attaaagttt ctgtttcctg tttttgtact tcctctttgc
    12301 ttattaaagc tttacaaaca aaattcggct caattctctc tattgcacct tttgacacta
    12361 atttttttat aacggtatac gtagtgtttc tattccatcc tgtttcttct tttaaaattt
    12421 ttactaactc tccagccttg ctttctcctc tctcccatag aacttccatt actttaagtt
    12481 ctgaatcaaa taattttatc tccatataaa atcgctcctc aaatatagtt atcacaatag
    12541 tcattactat aataaaaaac tatcatagta gtctatacta tgtcaatcat ttatttttta
    12601 ataataaaaa ctgtcttttt aaaaaattct tataaaagac agttttatca atgttatact
    12661 ttaatgttta attaaagcca tattttattt aaatatataa ctatctatct tagtacatag
    12721 tataagattt ttctttatct aatagtatat cctctacatc tgggttttct tttactaatt
    12781 gtctataaaa attacaatta gtaacaccta catatggaat tagccatagt agacctattc
    12841 caagagtagc tattgaaagt atataccatc ctataaaact aaagtttagt acaaataatt
    12901 taagtacatt tcctttcatc atatctaaac tagcacccat tgatttaaat acacccatat
    12961 tatccttgtc ttcacaaatt aagaaagtag cttgagaaac atataatagc aatatataaa
    13021 ccggtaacat aagaacaagt attataagaa ctagagttat tccagtagaa ataatagtcc
    13081 ctattccaac attatcactt gataaatatt caattgctcc actagtaagt aaaactccaa
    13141 atgataaaaa cgctcctata attgtgatta taaaagaata aatataaaca ataattgatt
    13201 caaataaata aaaaccaaaa cttcttaaat aaattctccc acttacaaag atatctccta
    13261 tcttgacttt ttcatcttta gtaattttca agaacataca tgtaaatcct gctgaaacgc
    13321 aaaaagctat tacagccact acaatagtag tcaatggttc aaaaggtaat cctacaattg
    13381 atattaatac tatcaatgca atatatactg ccatagaaat tgcacatatc ccccagtttc
    13441 cagataactg agctttagat actcgtttta attcttgcct tgataccata aaaaacaccc
    13501 ctttcatttt ataaaaaaac ttttaaaaat ataaataatc ttttaacgta taatattaat
    13561 atatcatatt ttcgactata taagatacaa ttattcacca tgttttatca agatatgcca
    13621 taattgtatt actagtttta tatagtcaac attaccaaat acatcaaata aatttgatta
    13681 attattcaac aagtaataa
//
LOCUS       DAEQAF010000098        13388 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.101, whole genome shotgun sequence.
ACCESSION   DAEQAF010000098 DAEQAF010000000
VERSION     DAEQAF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.101"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            169..1482
                     /locus_tag="KRN00_003016"
     CDS             169..1482
                     /locus_tag="KRN00_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1828870.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            1654..2829
                     /locus_tag="KRN00_003017"
     CDS             1654..2829
                     /locus_tag="KRN00_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBH1828871.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINIDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            2932..3951
                     /gene="hrcA"
                     /locus_tag="KRN00_003018"
     CDS             2932..3951
                     /gene="hrcA"
                     /locus_tag="KRN00_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBH1828872.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            3981..4601
                     /gene="grpE"
                     /locus_tag="KRN00_003019"
     CDS             3981..4601
                     /gene="grpE"
                     /locus_tag="KRN00_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBH1828873.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            4693..6540
                     /gene="dnaK"
                     /locus_tag="KRN00_003020"
     CDS             4693..6540
                     /gene="dnaK"
                     /locus_tag="KRN00_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBH1828874.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            6751..7905
                     /gene="dnaJ"
                     /locus_tag="KRN00_003021"
     CDS             6751..7905
                     /gene="dnaJ"
                     /locus_tag="KRN00_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBH1828875.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            8871..9806
                     /locus_tag="KRN00_003022"
     CDS             8871..9806
                     /locus_tag="KRN00_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBH1828876.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRAECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EDLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            9842..11215
                     /locus_tag="KRN00_003023"
     CDS             9842..11215
                     /locus_tag="KRN00_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1828877.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGAISFLLNFILK
                     KELRKVE"
     gene            complement(11403..12170)
                     /locus_tag="KRN00_003024"
     CDS             complement(11403..12170)
                     /locus_tag="KRN00_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1828878.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEILGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(12200..13309)
                     /gene="ugpC"
                     /locus_tag="KRN00_003025"
     CDS             complement(12200..13309)
                     /gene="ugpC"
                     /locus_tag="KRN00_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBH1828879.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNNIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
BASE COUNT         5145 a         1513 c         2354 g         4376 t
ORIGIN      
        1 aaataatttt tagagaatat tttagaagtt acgattgtat gatttttaaa tgcataggca
       61 tttactctag gactatagac taatataaaa aaaaactttg ggaatactaa aaccataaat
      121 ttataaaatt aatattttat atactgtaaa acagtgagga gggacagtat gcatactcaa
      181 ctacaaaaga ctattggtct ttcagcagct ctttctactg ttgtaggtat ggttataggt
      241 tcgggagttt tttttaagcc acaagcaata tacactacaa ctaatggagc tccaggttta
      301 ggtattatag cgtggctttt aggtggtttt ataacaataa ctgctgggct tacagctaca
      361 gaaatttcag ctgctatacc aaaaactggt ggtatgatga tttatatcga agaaatatat
      421 ggagaaaagt taggtttttt aactggatgg atgcaaactg tattattttt cccaggtaca
      481 tcagcagcat taggagtaat atttgctcaa caagcatctg aacttttagg aatgagccca
      541 aataatatgg caaatgtact tcctatagca attggagtta tactattttt agcattatta
      601 aatataatag gttcatcctt aggaggaaaa gttcagacag tagccactat tggaaagatg
      661 atacctttaa ttttaataat agtctttgga tttattaaag gtcaaagtag tgaagtatta
      721 aatccatttg taggagatgg tgtaaatgca tcaaatgcac ttggacaagt attaatagct
      781 actttgtttg catatgatgg ttggataaat gttggagcta tatcaggaga aatgaagtct
      841 ccagagaaag atttaccaag agcaatagtt ggtggtttat cattagttat ggcagtttat
      901 attataataa atatagctta tctttgggta gtaccagcaa gtgaattagc aacagttact
      961 tccccagcta cattagtagc aacaagattg tttggaaata taggtggaaa agtaataact
     1021 gtgggtatat taatatcagt atttgggaca ttgaatggat atttattaac aggttcaagg
     1081 ataccttata cattagctga aatgggaact ttaccagcat ctaaaactct tttaaaagta
     1141 aattctggag gttctcctgt aaattcaata ctacttataa ctgtgttagc ctgtgtatat
     1201 gcattatctg gtcaatttaa tcttttgaca gacttaacaa tattttcaat atgggtattt
     1261 tatgtattga cttttatagg tgttatgagg cttagaagac aaaagccaga tttacacaga
     1321 ccatataaag tccctttata tccaataata ccaattatag ctatattagg tggactgttt
     1381 gtaataataa atcaaatatt gacttcaaca gtcatatctt taggtggaat atttataaca
     1441 ctattaggtt taccagttta ttattatatg aaaaaaagat aactacttaa tttaagttag
     1501 ataaatttgg gtaaaggtga aaattaactt ttatccaaat tttttatact gttatacaat
     1561 ataagtatta tatattgctt gatgtgctat tttgtttgat ttataattta gtaattgatg
     1621 ttttaagata atttaagaaa tgaggagtga aagatgctag gactttatgt acatattcca
     1681 ttttgtgtga aaaaatgtaa gtattgtgat tttaattctt ataaaatgga catagattca
     1741 aaaaaaagat atatagaaga cttaaaaata gaaatggaat tatatagtaa taaattatat
     1801 aaagataata aatataaaaa taaagaatgc tgtagtctaa ataaaaatga caaaataacg
     1861 agtatatttg tagggggagg tacacctagt atactaacct ctgatgaaat aagagaagta
     1921 tttataagta taaaagaaat gtttgatata gatgagaatg cagaaataac tatagagtgt
     1981 aatcctggga cattaacatt agaaaaatta aaaactatga aagagattgg cataaataga
     2041 cttagtatag ggctacaagc tattcaagaa aagcatttga actttatagg aagaatacat
     2101 acttatgaag aatttgagaa aaactataaa gatgcattga gtgtaggttt taaaaatatt
     2161 aatatagatt taatgtacag tcttccaaat caaactctat gtgattggaa ggaaactctt
     2221 gaaaaagttg tacacttaaa tccaacacat atatcagctt attcccttat actagaagaa
     2281 ggaactgaac tatacaatat gtatgaaagt aataaatttg aacttataga tgaaaatgta
     2341 gatatagaaa tgtatgagta tacaataaac tacttaaagt caaaaggata taatcaatat
     2401 gaaatatcca actactcaaa agaaggctat aattgtgagc ataatatttt atattgggaa
     2461 tgtgaacatt atatagggat tggagcagga gcttctggct atattaatga gaacagatac
     2521 aataatgtag aatctttaga agattatcat ttaagtttgg taaaaagaga aaaaccaata
     2581 caagaaaatg aaattctttc tgagaaagat atgatagaag aaaagatatt tatggggctt
     2641 agaatgaata aaggcataaa atttgaagat tttaaaaaaa aatttggaat agattttaga
     2701 gagaagtata ataagcaaat agaaatgcta ttagctagaa agcttataaa tcagagcttt
     2761 gaaggtatac aattaactca aaaaggaaga gaaatatcta atagtgtatt tatagaattt
     2821 atggaataat ttttaaggtg ttgacaaaat aaatttataa tggtatataa tatatataat
     2881 ctttttagca ctcgaactta gtgagtgcta acagctagga ggtataataa tatggaatta
     2941 aatgaaagaa aattaaatat cctcaaagct atagttaaag attatataga aacagctgaa
     3001 gctataggtt ctagaacaat atctaaaaga catgatttag gtgttagtgc tgctaccata
     3061 agaaatgaaa tggctgacct tgaagaatta gggtatttaa ttcagcctca tacttctgcg
     3121 ggtagagttc catctgaaaa aggctataag ttatatgtaa actctcttat gagtaaaagc
     3181 gaattggatg ataatgataa gattcttatt gaacaatgta tgaatcacaa tataaatcat
     3241 ataaaagaat tgattcatga aacttctaag ctattatcgc aactaacaaa ctatacaact
     3301 gtagcagtta ctaagagttt aataaatcaa agtgttataa agcacataca gttggttgct
     3361 atgaatgaca ataatatttt acttatagtt gtaacagata aaggggactt aaaaaaagct
     3421 aaccttacaa ctaatgtata tttagatcaa tctaagttaa atttgatttc tgataatctt
     3481 acaaggaagc tcttaggtaa aagtataaca gatttggatg ataatctaat tgcttttatt
     3541 aaatacgaaa taagtgagta ttctgggctt atagatgagc ttttaaatgc tttgaactca
     3601 aatatgaaag aagaagattt ttctctatca ttaaatggag ctactaacat atttagttat
     3661 ccagaattta atgatgtatt aaaagcaaag tcatttttaa atatgttgga aaaaaaggaa
     3721 acaatagctg acataattaa atcaaaggga atacaaaaag acaatctaaa tataataatt
     3781 ggtagtgata atgattgtga actggcacag gattgtagta tagttacagc aacttataat
     3841 gtagatagag acttggttgg gcgaataagc tttataggcc ctaccagaat ggattatgct
     3901 agaatttact ctataataaa ttatatgagt ttattaatta atagaaagta aagaaatttt
     3961 aaattgcgag gtgtaaagtc ttggataaaa aaaatgagca acaggaagta agagaagaaa
     4021 atgatacttc tattaaccaa gaatcggaaa ctcaagtaga gttagaagag gaagttgtta
     4081 atgaagaatg tgaaacatca agtgaaaaaa ctgatgaaaa agaagttgat gatgaaaatg
     4141 taacagatat aaattctaag ttagcagaaa aaaaattgca ggatgagttg gatgaattaa
     4201 atgataaata tcaaagactt caagccgaat atgcaaacta cagaagaaga actcaacaag
     4261 agaaagagac aataggtgta tttgcaaatg aaaaaataat aactgaattg ataccagtta
     4321 tagatagtat ggaaagagcc ttagatgcat gtgaagataa ggaagatact atgtataagg
     4381 gtataagcct tgtacataaa caattaatag acactttagt aaaatttgga gtagaagaaa
     4441 tagaagcaga atctaaggaa tttgacccta atctacatct agcagttatg caagaaagtg
     4501 tagatggagt tgaagcaaat caaatagtaa tggtacttca aaaaggatat aagctaggaa
     4561 ctaaagttgt aagaccttca atggttaaag tttcttgcta agtataaatt aaaggttaaa
     4621 ttatttaacc taatataaaa tattaaaata agtaaaactt aattatataa ttactcgagg
     4681 aggattttag tcatgggaaa aataatagga atagatttag gaacaacaaa ttcatgtgtt
     4741 gcagtgttag aaggtggaga agcacaaata atagcaaata gtgaaggtat gagaactact
     4801 ccatcagtag tagcatttac aaaagatggt gaaagaatag ttggagaacc tgcaaaaaga
     4861 caagcagtta caaatgcaga taaaacaata acttctataa aaactcatat gggaactgat
     4921 tataaagtaa atatagatgg aaaatcatat actccacaag aaatatcagc aataatatta
     4981 caaaaattaa aatcagatgc agaaagttac ttaggacaaa cagtaacaga agcagttata
     5041 acagtaccag cttactttac agatgctcaa agacaagcaa ctaaagatgc tggtagaata
     5101 gcagggcttg atgttaagag aataataaat gagccaacag cagcagctct tgcttatggt
     5161 atggataaat tagaccaaga aaagaaaata ttagtatttg acttaggtgg aggaactttt
     5221 gacgtatcta tacttgaaat aggagatgga acttttgaag ttttagctac agctggtaac
     5281 aatagattag gtggagatga ctttgaccaa atagtaatag attatttagc agaggaattt
     5341 aaaaaagctg aaggtgtaga tttaagaaat gataaaatgg ctcttcaaag attaaaagaa
     5401 gcagcagaaa aggctaagaa agaattatca tcaacaatga gttcaaacat aaacttacct
     5461 ttcataactg ctacagcaga aggaccaaaa cacttaaata tagatttatc aagagctaaa
     5521 tttgaagaat taactagagg tttagttgaa aaaactatgg aaccaactaa gacagcttta
     5581 caagatgcag gactttctac aggtgatata gatgatgtat tattagtagg tggttctaca
     5641 agaataccag cagtacaaga agctgttaag aagtttatag gaaaagaacc tcataaaggt
     5701 ataaacccag atgagtgtgt tgcagcaggt gcttctatac aagctggagt tttagcaggg
     5761 gatgttaaag acttattatt actagatgtt actccattat ctcttggtat agaaactatg
     5821 ggtaatgtaa tgactaagat aatagaaaga aatactacaa taccaactaa gaagtctcaa
     5881 atattctcaa ctgctgctga taaccaaaca gctgttgata tacatgttct tcaaggtgaa
     5941 agaagtatgg cttatgacaa tacaacttta ggaagattcc aattaacaga tataccacca
     6001 gcacaaagag gaatacctca aatagaagtt acttttgata tagatgcaaa tggtatagtt
     6061 aatgtttcag ctaaagattt aggtacagga aaagagcaaa aaataactat aacatcaaac
     6121 actaatttat cagaagcaga aatagagcaa aagataaaag aagcagaaat gaatgcagaa
     6181 gctgacaaac aaaagaaaga aaaaatagaa gcattcaatc aagctgaatc tactatatat
     6241 caaactgaaa aaactttaaa tgaacttgga gataaaataa gttcaggtga aaaagaggat
     6301 atagaaaaag ctatagcaga cttaaaagct gtaaaagata atcaagatgc tacagcagaa
     6361 gaacttaaga aagctacaga tgaagtaatg actaagttcc aaaaagtatc tcaagaaatg
     6421 taccaaaaag cagctcaaga acaacaagcg gcacaaggtg cagaacaagc acaagacaat
     6481 ggacctaaag atgacaatgt agtagatgct gactttaaag aagtagatga agataaataa
     6541 gctatataat atgtaacact aaatgataat tggaacatat atgatttgtg aaaatcatat
     6601 agatgttaaa gatatatgga caatatacat cataaagaat ataatatatc atagattata
     6661 taacttaaag tagaatataa gaattaatga tagcttgtag tttattattc tacaagctat
     6721 cgttttgtaa aatgaaggtg gtgtcaattt ttgagtacaa aaagggatta ttatgaagtc
     6781 ttaggtatca gtaaaggtgc agaagctcaa gagataaaaa aagcttatag aaaattagca
     6841 atgaagtacc atccagatag aaatcctgga gataaagagg cggaagaaaa atttaaagag
     6901 ataaatgaag cttatgaagt tctatctgat gatacaaaga gaaaaactta tgatcagttt
     6961 ggacatgatg ggctaaatgg tcaaggcggt tttggtggtc aaggaggatt tggcggtcaa
     7021 ggctttggtg gttttgaaga tatgttcgga gatatatttg gtgacatgtt tggaggaagc
     7081 ttcggaggtg gaagagcaag aagaagagga cctcaacgtg gtgcagatat aagacagagt
     7141 gttactatat cttttgaaga agctgcattt ggtaaaaaga tgtctataaa agtaaataga
     7201 agtgaagagt gtgaagaatg taatggaact ggagcaaaac caggaacatc aaagaaaact
     7261 tgttcaactt gtaatggaac tggtcaagtt agaactgttc aaagaactcc atttggtaat
     7321 atagcaagtt caagaccatg tagtgcttgt aatggaactg gagaagtgat tgaatctcca
     7381 tgtagtaaat gtcatggaac tggaaataca agaaaagtta agactataga agtagatata
     7441 cctgctggta tagatgatgg tcaaatgata aaactttctg gtcaaggtga agtaggagaa
     7501 aaaggtgctc caagaggaga cttatatatt gtagttaatg ttaagtcaca tccactattt
     7561 actagagatg gaaatgatat ttattttgaa atgccaatta catttgttca agcaacttta
     7621 ggtgatgaga tagaagtacc tactttggat ggaaaagtta aatatagtgt gccagagggg
     7681 acacaaactg gaactgtatt tagacttaaa gagaaaggaa tccctagaat tagaggtaat
     7741 tcaagaggag accaatatgt taaggttgta gttgaaattc ctaaaaaatt aaacgataag
     7801 caaaaagaac tattgagaga atttgcgaag gagtgtgggt cgaacgtcca cgaaaagaag
     7861 aaaaccttcg gacaaaagat agaagatatg tttaagaaaa agtagttaaa gtagccaata
     7921 tataatcata tttttaaaat cttagttatt tataagattg tcaaaggaga tattatgatt
     7981 tttatattgg ctatttttgt ataaaaaata aatgtgcata aaataaaact gaatataaat
     8041 aattttctga aaaatacttg tcctaaaata tataatatgc tataatataa tcaaataaaa
     8101 gaaaggggtg attccagtgg gaacggatgt ggcactgcca aatgatgaag aaaactttat
     8161 tgtaatatac aaaataaaat tagatacttt tagtgctaga ttaagtactg gaaaaactca
     8221 tgagctggga taattattgt aattacctag actcaaactt ttagtagtaa aatagtaata
     8281 ttatatagac aaggtatcta atttttaaat cttttgtatg aattaaaatt tttataaagg
     8341 gtatatctga ttagaatgta attagggaaa cctagttgtg aattactttt agtatataca
     8401 tgtgtaaaga aatatgtata tggtattggt tattgtgcta gatgtgtatg taaaggaata
     8461 tgtgtctagt tgggtatatg taaagaaata tacttataat ctatgaaaaa tttttagtat
     8521 aaattgctaa aacattgaga ttgtttttta tagaaagtta gtttatacca actaaaaatg
     8581 tgcttaagat ttgtttgatg tttaattata aataaggttg tagataaaaa aataagtaaa
     8641 gacaaaggtt taaaatactt gctttaaata tagtttgttt tgaacacttg ccaaattaaa
     8701 ataattaata aaatagacat cttctcatag taaaatatac tgtgagagga tgtttttgct
     8761 ttgttcataa acttttatga aaaatttgca tagtgtcaca ttttaatata ctatatatat
     8821 aataaaatat agataaaatt aaatgattca aaagagaaag gtgaaaagag atgtattata
     8881 taggtgtaga cataggagga acaggtatac aagcaggagt agttgataac tatgggaaaa
     8941 taatttttag ggcagagtgt aaaacagtaa ttgaaaaagg ctttgaagga atacttaatg
     9001 acataaaaat aatgatttat aagttgttgg aagataataa acttactatg agtgacataa
     9061 aatctattgg atttggtgtt ccaggtttta taaataaaga aggattagta acttgtgtaa
     9121 atttaaaatg gaataaaaaa gcttttaata aagagttaaa aagaagattt ccagatgttg
     9181 aaattcatgg agaaaatgat gcaacagtag cagcacttgg agaggcaaag tttggaagta
     9241 tgaaaggtgc taatgttgga gtattatata ctttaggaac tggtgtaggt ggaggaatag
     9301 taattaatca aaaagtcttt tctggagcac atggattggg ttcagaaata ggtcatcaaa
     9361 ttataggaga aaactatttt aattgtaatt gtggaaataa tggttgtgta gaaacttttt
     9421 gttcagcaac tgcaattata aagtattctc aaaaactgat agaagaagga gaaaagagta
     9481 ggattttaga tttggcagag ggaaatttag aaaatgtaaa tgcaaagatg gtgtttgatg
     9541 catatagaga aaatgattta gtggcaatta aagtaataaa tagatttaaa gagtatttag
     9601 caaaaacttt tgcaaacaca ataaattctt tagacccaga aattatatct ataggaggag
     9661 gcatttctaa atctagcgat ataatacttg atggaataga agatttggta agaaaatttg
     9721 tattatacaa aacagaagat atagctacaa ttacatgtgc aactttaggt tcagacgcag
     9781 gaattatagg agcagctttt ttataatgta aatgaactgc ttattggagg cgtgatgata
     9841 tatgggtaaa acaaatgcta gaagaacgct ttttttgata gcaataggtt caggaactat
     9901 gctgaatcct cttaattctt ctatgatttc acttgcttta catagtatac aaaatgattt
     9961 tcatattagt tttacaactg tatcttggat tgtttcagca ttttacctag ctagtgctat
    10021 tgcacaacca gtttcaggta agataggaga tttaataggt agaaaggtct tatttttgag
    10081 tggtttgatg cttgtaattt tatcagcatc catagtacca cttgttcaat cattctttat
    10141 attgattttt ataagagtaa ttcaagcaat tggaacaagt accctatatc catctggagt
    10201 tgctcttata caaaataata taaaagaaag acaatcttct gcattagcag ttctaaccat
    10261 ttttgcttca actacagcag gattaggtcc gacacttgga ggattattgt tggacttagg
    10321 aggatggcat gctatatttc ttgtaaatat acctgttgtt ttggtttcta tatgcttagg
    10381 gtatttttta ttcccaaaag aagtaaaaga aaagaaatct ataaaagaaa ctttaaaaaa
    10441 tgttttgtca agattagata ttattggcat acttctattt tcaattgcaa tgatttttat
    10501 attactattt ttgctatcta tgaaggaatc ttttaactta gaacaacttg tatttggtat
    10561 aatactgatg tgtcttttta tttggcatga attgagaaca aaattgccat ttatagatat
    10621 taagcttttt gtaagtaatc ctaaattgtc aaaagtttac ttgcaattta ttatattaaa
    10681 tttctttaat tatattttgt tttttggtct tcctagttat tttcaagatg ccttacatta
    10741 tagtgcaaag tcgactggat tatttatgct atttatgtct ggtataggta tatttatatc
    10801 tccattaact ggaaaatgga tagataaatc tggaactaga tttcctcttg ttacatcatc
    10861 aatctttatg tttattagtg cagtacttct ttcagtagtt tttatccata tacctgtaat
    10921 aggaaagggt attatattat cattagcagg tattagttat ggagttggta atgtagccct
    10981 gcaatcctct atgtttgaag aaagtcctcg tgacagtata gggacagctt ctggtctgtt
    11041 tcaaactagt cgttatttag gttctatttt agcaactgtt ttacttggaa tggtatttga
    11101 agtaaatata acatcagaac aatttcagat attaggttat gttatggtgg tcttaggtgc
    11161 aataagtttt ttattaaatt ttatattaaa gaaagaatta agaaaagtag aatagtggat
    11221 ttatggattt aataagtcta ataactgata agtttaaaaa tattgtttgt aaaacataac
    11281 tggtttgata tttattaatt ctaagttttg aagcatagag tactcgataa gtatacaata
    11341 ttttgaatta aaattaagca gaaatttgaa ctagtctttc aaatctctgc ttaatttagt
    11401 agttaaattt ttttatagag aaaataagat ttgacactta gataaaaaat cattgcattt
    11461 tcaaaattct ttaaatcaaa cccaagtatc tcattaatct tttccaatct atatactagc
    11521 gtgtttctat gtaaaaacat actagtagat gtcttagaaa tatttaaatc attatttata
    11581 aattttattc ctgtatatag aagttcttcg tcaatagatt taatcttatt aaaatctatt
    11641 aatttattga gtatattatc ctcattaatt aaatctaaag ttttatatct aataaggtca
    11701 aacaaattta aaaacttatt ttcagcgttg tcttttataa tatgaggtag taaatcagaa
    11761 cataactgta atctaaaatc aaaatcagct ttactatcta atttaccaag ataaaaaata
    11821 taagtacttt gataagtttc agtttcaatt atattttgtg tagttacatt aatatctaag
    11881 ttatatttag aatttactat aaaaaaacca ttgtgttgta ttatatttat atcttcaaat
    11941 aaattataaa aaatattttt tagatattca aagtctatat gagattggta aattaaataa
    12001 aagttgcctt ttaaattatc aagattattt ttatctagaa aatcaataac ataaatagca
    12061 ttattgaaag taactaaatg gctactagca tctaactttt ggttttcata tggatagata
    12121 tttatttttt tattaagctg tctttctaaa aaatctttta actcttccat aaagtctcct
    12181 taaaaataag attatattct tatcttatag ctaaagtagt ttctttgtca aatatgtgta
    12241 ctctactgtt gtcaactgaa agtgttaagt catcaccaac attaattctg tttttactgt
    12301 caaatctaat tgttatcgta ttttcgccta gttttaagtg agcataagtt tctgctccca
    12361 taagttcttt tatttcaatt cttgatttaa aacaagtatc tggattagat ttaataaaag
    12421 tatcttctac atgaatatct tctggtctga tacctataac aacttcatta ttaatataat
    12481 tgtcttttat taaatcatag tgtttttctt tattcaattt aagcttaata tgttcatttt
    12541 gtgcataaat ttcatcattt tcttctatta atattacatc aataaaattc atctgtggtg
    12601 ctccaataaa tcctgcaaca aatatattag ctggataatc gtatacatct tgtggagttg
    12661 caatctgctg aactactcca tccttcatta ctacgattct atcagccata gtcatagctt
    12721 caacttggtc gtgtgttaca tagataaatg tagttccaag ctgttggtgt agcttagtta
    12781 tctctgttct catagcagtt ctaagttttg catctaagtt ggatagaggt tcatccatta
    12841 agaatacctt aggatttcta actattgcac gtcctaaggc aaccctttgt ctttgtcctc
    12901 cagataatgt tttaggtttt ttatttaaaa gaggtagtaa gtctaatatt ttagcagctt
    12961 ctttaacttt tttgtctatt tcatctttag gcaattttct aagtttaagt gcaaatgcca
    13021 tgttttcgta aacagataag tggggatata aagcatagtt ttgaaaaacc atagctatat
    13081 ctctatcttt tggttctata ttattgacaa gtttatctcc aatgtatagt tctccttcag
    13141 agatttcttc aagaccagca atcattctaa gtgtagtcga tttaccacaa ccagatggtc
    13201 ctactaaaac gataaattct ttatctttaa tgtctatatt tatatttttt actgcattaa
    13261 atccatttga gtaaagtttt gatatatttt ttaaaattac ttctgacata atatcctcct
    13321 tgatatttaa attttaatta tatagtatca aattttttta ttatattaaa tgtgtaaaat
    13381 gactaaat
//
LOCUS       DAEQAF010000099        13311 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.102, whole genome shotgun sequence.
ACCESSION   DAEQAF010000099 DAEQAF010000000
VERSION     DAEQAF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.102"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            485..2005
                     /locus_tag="KRN00_003026"
     CDS             485..2005
                     /locus_tag="KRN00_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1828880.1"
                     /translation="MKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIII
                     SIIGILACIILILQYSKKMIRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIH
                     KDKKFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVA
                     LRCYVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINR
                     ANFAQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHS
                     QKINCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIKKRLDENK
                     PFVQISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIH
                     DLHENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHM
                     LKELNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEEILDKEFVYNS"
     gene            complement(2279..2878)
                     /locus_tag="KRN00_003027"
     CDS             complement(2279..2878)
                     /locus_tag="KRN00_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1828881.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNAQGENLRIN
                     GNKIKEIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKDHREMDTEFHWGLKWVAGRK"
     gene            complement(2981..3778)
                     /locus_tag="KRN00_003028"
     CDS             complement(2981..3778)
                     /locus_tag="KRN00_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBH1828882.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3891..3996)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4088..5074)
                     /locus_tag="KRN00_003029"
     CDS             complement(4088..5074)
                     /locus_tag="KRN00_003029"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBH1828883.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPIVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5557..7287
                     /locus_tag="KRN00_003030"
     CDS             5557..7287
                     /locus_tag="KRN00_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBH1828884.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVAELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFIGIQIIGKR
                     VDEAEIELVE"
     gene            7397..7477
                     /locus_tag="KRN00_003031"
     tRNA            7397..7477
                     /locus_tag="KRN00_003031"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7431..7433,aa:Leu,seq:tag)
     gene            7812..8326
                     /locus_tag="KRN00_003032"
                     /pseudo
     CDS             7812..8326
                     /locus_tag="KRN00_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
     regulatory      8802..8906
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9116..11590
                     /gene="gcvPA"
                     /locus_tag="KRN00_003033"
     CDS             9116..11590
                     /gene="gcvPA"
                     /locus_tag="KRN00_003033"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBH1828885.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISTLKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGSLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSVLRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYMATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11590..13047
                     /gene="gcvPB"
                     /locus_tag="KRN00_003034"
     CDS             11590..13047
                     /gene="gcvPB"
                     /locus_tag="KRN00_003034"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBH1828886.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIEDMIDPDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RSYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
BASE COUNT         4989 a         1586 c         2187 g         4549 t
ORIGIN      
        1 actctaaagg tgaactatgt aaaacaaggt ttatatattc taattgtata gaaaaattta
       61 ttgtaaacgc atgtatatta ttagaaaaaa tagtttggag atattcaata aacataaaaa
      121 acaatatagg ggataaaggt gttttatgaa gagatttttg aggagaatta tcttagtttt
      181 atttatttta ttgattttta taagttttat ttctattaaa ttaattcata atgttgaaga
      241 ttgttgaaaa ttgattaatt atgttgggat tgttcgtgga gctagccaac gtctaactaa
      301 actagagatg aatcatcaac caaatgatga attaatagaa tatattgatg aaatactaca
      361 ggaattgatt acagggcatg gagattatgg tttagtaatc actgattgta atgaatataa
      421 tgaggactta cttttattag aaaaaaagtg ggaagattta aatattgaaa ttaaaaaagt
      481 aagaatgaaa gaacagaata accagttatt aagtataagt gaagagtttt tttctcttgc
      541 aaatgataca gtgtttaaaa tagaaaactt ttctaaagaa aaaagtaatt acttaatgac
      601 tttaataata attatatcta ttataggtat attagcatgt atcatattga ttttacaata
      661 tagtaaaaaa atgattagac tggagaaatt aaatgtagat ttaaaaaata ttgcatataa
      721 agatgaacta acaggagtaa atactataga aaaatttaaa ttggatgcaa atcaaaatat
      781 ttgtatacat aaggataaga aatttgctgt attctatatt gattttgaaa actttaaata
      841 cattaatgat atatttggat atgattatgg tgacatgata ctgaaaagat atgctaatct
      901 tatgatgaat gatataggga aatatgaaat atttgcaaga gaaattgcag atagatttgt
      961 tgcgttaaga tgctatgtag ataaggaaga tttagtagta aggcaacgag atgtagacaa
     1021 tgaactaatt aatataacaa atgaaattaa aaataaacat agcattactg ttgttagtgg
     1081 aatttgttgt attgaagatg taaatgaaaa attaagtata gatggtttaa taaatagagc
     1141 aaattttgca caaaaaactg ttaagaataa accaggtact aattatgctt tttataatga
     1201 cagtattcgt aaaaaaatga ttgaagaaaa tactatcaag agtagaatac atgaagctat
     1261 tgaaaaaaga gaatttatag tttatttaca gcctaaagtt aatttacata gtcaaaaaat
     1321 aaattgtgca gaagctttag ttcgttggct gactccggat aaaggtatta tatctccagc
     1381 aatatttatt ccagtacttg agaagaattt ttttattgcc ttagtagata agtatgtttt
     1441 tgaggaagtt tgtaaatgga ttaaaaagag gttagatgaa aataaacctt ttgttcagat
     1501 atcagttaat gtttccagaa tacaatttta taacactaaa tttgtagaaa cttattccaa
     1561 catacaaaat aaatacagga tacctaaaaa tactatagaa attgaattta cagagagtgt
     1621 tgcttttgag aatcaaaaac atcttttgga aattatacat gatttgcatg aaaatggatt
     1681 tacttgttct ttagatgatt ttggaaaagg ttattcgtct ttaagtgttt taaaagattt
     1741 accatttgat gttttaaagc ttgactctat gtttttcaag gctagtttag ataaagataa
     1801 agagaaaata gtaataaaaa atattgtaca tatgttaaaa gagcttaata tcacaactgt
     1861 tgctgagggc attgaatgca aggaacaagt tgaatttctt agggatattg ggtgtgattt
     1921 agttcaggga tttgtatttt ataaaccaat gccaatatta gaatttgaag aaatattgga
     1981 taaagagttt gtttataata gctaaaatgt actttataaa atatgaacta attaagtaaa
     2041 attattttgt actgaataaa tttttacttt atttacagaa tagtgcgaaa agtacactcc
     2101 tttaagtgtg ggatggatag tacaaatagt gtataaaaaa tattgaccat ataagaatgc
     2161 ataatgatat aaatatttga aaggtcacta ttatatgaaa attaaaaaga aaataaataa
     2221 tttttctata aaaaagagac tatgagaaaa gttactcata gtctcctaaa taatgtattt
     2281 attttcttcc tgcaacccat tttaagcccc aatgaaattc agtatccatt tctctatgat
     2341 ctttgaagta tttaactact ttttcaacac tgaatgtctc atcatttaca ttttctatca
     2401 atgctattga acacatatta tagccatttt tatgttcatc aagtttgaca actaagtctg
     2461 aatcttgttt ttgtttgatt gttacaattc catcagcttc tgaccaatta gccacacctt
     2521 cataaataaa agcataaatc aatattcttt ttatttcttt tatcttgtta ccatttattc
     2581 ttaaattttc tccttgtgca ttacttcctg ttctgtcatc tccatctaat tgagcaaaag
     2641 gtggattgtc taaactacca aaagcatttc ctaatgcttg aacagcacct tttacaccat
     2701 ttttcatctc aaataggcaa cccaaatcta aatctatatt actgcttctt aaagagccaa
     2761 aaaaaccctt tttttgtact ttttgattcc aatttaaatt aactaagatt tcacctaaat
     2821 cgctattttc cttttttgta aggtttattt tttgtccctt ttttaattct atagccatag
     2881 taatcttcct ccacaaacat agatttattt aaatggtagc acttaataag tcaatattca
     2941 acaagattag aataataata ttaaaattat actaaatata ctaaaaagta ggaatcacaa
     3001 tacctttgta tttttcttca attaagcttc ttgctttatc tgatgtaaga acatcttgta
     3061 gaactttaat cttttcactg tctttatctt cagttctaaa tgctaaaaga tttgcatact
     3121 cgtcatttat aggagctgta taaattccgt ttttcttggc atcaagacca gcaggtacag
     3181 cataagtagt atctataaat gcagcagtca catctggaag agaagatgga atttgagcaa
     3241 tatctaactc tttgaattgt attccctttg gattttctat tatgtcctta ggactaacta
     3301 atccatcccc tttaggtaac gttaaaagtc caatactttc aaggtatcta aggttcttag
     3361 aacaagaaga tgggttattg cttattgcaa ttgtatctcc ttttttaaat tcatcaacag
     3421 attttatctt ataagagtaa agtattgctg ggcatacata tagtttttta ccagccatta
     3481 ttttgtaacc tttggcctta acagcttctt ttagataagg ttcatgttga aatagatttg
     3541 catcaatttc accattattt aaagcttcgt ttggaagtat gtaatcatca aagtttttaa
     3601 cttctaaagt atatcctttt tctttaataa gtggttttaa ttcttctaat aactctcctc
     3661 ctggaactaa agtagcacca acaacaattt ttttatcatc tttagcttta gaacatccaa
     3721 ccacagctaa agttaatact agacataata acaaacataa taattttttg aatttcatat
     3781 aaattccctc ctgaatataa ttgattagtt aaaaataaaa taccattctt tatcacactg
     3841 caaaataaaa ataagcctga gtttaaactc aggctttaaa agctaattta gactcatctt
     3901 tcagtataat actgcaggat ttagcaccaa tgtatataaa aatatactgg ttgctgggtt
     3961 tcatagggcc agtcccttca ccactctgga taagaagtat caatttttaa ttatgttata
     4021 aatattatca tgatttttta cgtctgtaaa cataatttta taaatatttt aaaatcttta
     4081 atgtatttta cttaacacct aaaattccag aaactagaat atcagtatca gcacctaaga
     4141 aatagtcatt tatttcaata gaatccagag tatttctcaa agcattttct tcatgcctta
     4201 taccaataag tttattttct acaaatgcaa catcacattt tccaaaaaaa tctccaaaaa
     4261 attttatact agttattatg cctttatcaa catttaaatt aaactcaaca tttccaccag
     4321 aatattttaa ttcatttgaa agagtatatt ttggtgaatt accaaaattc caatcccaag
     4381 tttcgtattt tgatttagta agcttttcta tttgttttat atcatgttca ctcaaacaat
     4441 aattagtatt atcagtattt gttttagaaa gataatccat tatagcatct ttaaattcta
     4501 atatgtccat tttagagtgt aaatgttcac ttatattggt tacacgagat tttacagatt
     4561 ttattccttt tccttcaaat tttataggtt taacctttaa tgcttttgag aggtcattta
     4621 tttcagatga aaataaaagt gtaccatgat gcattacttt atttttgtag ttgtattgag
     4681 catttccaga aaatttcttg ccatctataa gaaggtcatt tcttccagaa aattcagcat
     4741 tgacatctag tgttttaagt aaatctatta tgggttgagt gaatcttctg aaatcactaa
     4801 aattattatt gttacaagct ataaatgtaa aatttatatt tcctaaatca tgaaatacag
     4861 ctccaccacc agactgtctc ctaacgatag gtatagaata ttcttttata tattctaaat
     4921 ttatttcaga aagtgtgttt tggttttttc caacaattat agaaggttca ttcctccata
     4981 aaataaataa gtcttcatca aaatttttta gaagatattc ttccattgct aaattaaaat
     5041 aagggtttgt tttttcatta taaattaata acattaaagt agttcctcca tataattgat
     5101 aaaattttta ttatgaatac aattaatttt ataattcgac aataatgtaa aaactccttt
     5161 aaattagaaa ttttaaaaac taccttgcaa agtttaaata aataatatat actcaaaata
     5221 tgtttaataa aagtgaatag aagggtagag gcgcaataat ctatcagtac taataaggag
     5281 ttaagcacag agagttatta ggaaaggaga tattgccgaa gttttataat cgatgcttta
     5341 agattatatt gctgggggta catagaaaat atgtacaact gtcacaggtt tatttgtggt
     5401 gagctatcat ttaaggaatt atattatatt tatttttact attgttgata tattgtaatg
     5461 tttaagcctt gagtgtttac cactcaaggc ttttttagtt ttattgtaac aaataccctg
     5521 tacagttcac aaaattaaaa agagagggag atttatatga ggaacaaaaa aattaatatt
     5581 atttttctga cgacaatcat gtttataatg tcaacagtaa tggtttttgc agaagaagat
     5641 atagacacta ttgcactagc taatgcagaa aaatttggga ttttaacttt aataccacca
     5701 ttagttgcta taatacttgc atttataact aaaaacgtaa taatttcttt acttataggt
     5761 attctttctg gtagttttat aattaaagct agtggtatta atgtttttgc gacatttata
     5821 caggcatttt tagatttagt agatagagct ttagtatctt tagcagaccc ttggaatgca
     5881 gggataatac tacaggtttt ggcaattgga ggagtaataa atcttgttgc taaaatggga
     5941 ggagctaaag ctatagctga agcacttgct aaaagagcaa agtcagcaaa agggacacag
     6001 cttataacat ggtttttggg gcttttagta ttctttgatg attatgccaa ttcactaata
     6061 gtaggtccta tgatgagacc tgttgcagat aaaatgaaaa tatcaaggga aaaactagcc
     6121 tttataatag atgctacagc agcaccagtt gctggtttag ctataatatc tacatggata
     6181 ggtcttgagg ttggtttaat acatgatgct tttgaaagta taagtataga tgtagatgca
     6241 tttggtatat ttttaaatac aataccattt agattttaca atatattaat attggcgttc
     6301 attgtaatat cagcattatt attaaaagaa tttggaccaa tgagaaaagc tgagataaaa
     6361 tctagaagca gaaaaattag tatagacctt gatgaaggcg tagcagagtt ggatgattta
     6421 gctccaaaaa atggagtaaa attgagtgta tggaatgcta taatcccaat agggacattg
     6481 ataatagttg cattagcatc attttattat agtggatata catctataat gggaggagat
     6541 gataaggctc tgatacaact atttacaaat tctccatatt cttttgaagc aataaaagaa
     6601 gcatttagtg catctgatgc atctagagca ttattccagt ctgcacttgt tgcaagttta
     6661 gttgctatta taatggctgt agtaaaaaag atttttacaa tatcggaagc aattgatgtt
     6721 tggatagatg gaatgaaaag tttagtaatc actggtgtaa tattaatact tgcatggtca
     6781 ttaagttcag taataaaaga gttaggtaca gctaaatttt taatacacct attatcaggt
     6841 tcactaccac cattcttatt accaagttta atatttggtt taggagcaat aatatctttt
     6901 gctactggaa cagcttatgg aacaatgggt atacttatgc cacttgcaat tccattagca
     6961 tactcattaa atcctgatat gtcttatgta atagtaagta ctagtgcagt tttaacaggt
     7021 gcaatatttg gagaccattg ttctccaatt tcagatacaa caatactttc ttcaatggga
     7081 gctggctgta atcatataga ccatgttaac actcaaatgc catatgctat atttacagca
     7141 gtaatcacta ttgtatttgg gtatatacca gctggacttg gattgccaat atatatagta
     7201 ttaccagtgg caatagctgc tatatttata ggtattcaaa taattggtaa gagagttgat
     7261 gaagcggaaa tagaacttgt agaataaaga tataaataag tttcaccttt tattatcatt
     7321 attttgttag tttttagata attttaaaaa gttattgaaa ataatagcga aatatagtaa
     7381 aataaaagag tgataagcgg atgtggcgga attggcagac gcactagact taggatctag
     7441 cgccattggc gtgggggttc gactcccttc atccgcactt tacagtactt aattgtactg
     7501 aaaaaaactg gggttgctgg ctttcggagt gggctatccc gtttttattt ttttgtatat
     7561 atgatagatt ggcactttag tataaagtgc tttttttata ggcaaaaaca gtacatttat
     7621 ttctgtttta ttatcattca tctattagag catactttag ttaagaatgt gttaacaagc
     7681 agtgttcaca ttcttgataa aatgtggaat aatatgtatc tttactaaga cggaaatgaa
     7741 gtaattaaac tattaaataa tattataaga cgataaataa gtagataaat taaattttgt
     7801 aggaggatgt tatggaaaaa tatatatggt tgtttccatt actttttatt tttcatgata
     7861 tggaagagat aataggtttt ggaatatggc ttaaaaaaaa taaatcaatg cttgataaga
     7921 agtatccatt tatcagtaaa atttatgaaa attatagtac tgataaatgg catttgctgt
     7981 gtttgaagaa tttattttat gcattatttt ctgtatactt atagttataa cagataatca
     8041 gtatgtatat ttactatggt taggtagttt tatcgcatat actttacatt tggtaattca
     8101 tatagggcag tcaatcataa taagaaaata tataccttca cttattacca gtatcatatg
     8161 cctaccaata agcatttggt gtataagtaa gagtatttat atagttgatt gtgaaatgag
     8221 tacaacaatt ctgtacagta taattggtat tataattgta gcattgaatt taaagtttgc
     8281 acagtcgctg attggaaaat ttacaaagtg gatgtcaaac atataaattt cagtttattg
     8341 ggcagttcaa ggagtcagaa attggagttt tatagtctta atataatgta taaaatttta
     8401 tagcaatgta tttcataagt ataaagtgac tagaacttta agaaatatac aaattctata
     8461 gaaactaaat agtttcaagt atattttaaa aatcttattt ttcacaagtt taaaattgta
     8521 aacgatttca tcaagtctat gaatatactt ttaacatgtt atagtaaatc tcaatataaa
     8581 tttacatttg gttctttgtg tgttatttta ataataaatt aagtgaaaat gttattttac
     8641 attaatatat aatatctttg cataagagtg aataatataa aagagaaata attgataata
     8701 aaaacttaac aaaaaaatta atacataaaa aaaaataaat ataatgtgtt gacatttaat
     8761 tgaaatattc atacaataaa attgaaaata aatatttcca aatgagatta gcgagagagt
     8821 cctttatacg aaaaggcgcc gaagaagaaa tttaagaaat gccaattttt agagaagctt
     8881 tcaggcaaaa atatcgctaa ttgatgggac tctggagaga cttaagttaa gatactataa
     8941 gtcaccgaag aagcaaaata atattaaatt attaaatctt tcaggtatac aaacagggat
     9001 atataggcta ggattatttt ctatgctgat atatcttttt tttatgaaaa agtacaggaa
     9061 ataatatcaa agttacttaa atacagtagg tctaatttta tagggagggt tatatatgaa
     9121 tgaattgaaa agagtatctt tgtacaatat acacaaagag cttggagcaa aacttgttga
     9181 atttgctggc tgggaaatgc ctttagaata tgaaggtata aataaagagc atgagaaggt
     9241 cagaaaaagt gcaggtatat ttgatgtatc tcatatggga gaggtacaga taaagggagc
     9301 agagtcagaa aaatttatac aaaacctagt tacaaatgat ataagcacat taaagataaa
     9361 tgacattata tatacaccta tgtgttatga aaatggtgga gtagttgatg atttattaat
     9421 atataaattt ggtgaagaag attatttatt agtaataaat gcaggtaata tagataaaga
     9481 tgtagcatgg ataataaaac aaagtgaagg atacaatgta gatataaaaa atatatctag
     9541 tgaagtgagt caattagcaa ttcaaggacc taaagcagaa gaaattcttc aaaaaatcac
     9601 agatatagac ttaaactcaa taaaatttta taagtcaatt ccatcaacaa aagtatgtgg
     9661 ttgtccttgt ttagtttcaa gaacaggata tactggggaa gatgggtttg agatatactg
     9721 taaaaataaa tatgtagaaa taatttggaa tgaagttcta aaggttggag gagaagatat
     9781 atgtccagct ggtctaggtt gtagggatac tttgagattt gaagcagctc tacctctata
     9841 tggacatgaa ataaatgaac atatatctcc aattgaaggt agtttatcta tctttgtgaa
     9901 aacaaataaa gaatcattta ttggcaaatc aattttatca aaagaaaaag aaagtggagc
     9961 taaaagaaag ttagtaggat ttgaaatgca aggcaaagga atgcctagaa atggatatga
    10021 tataaggatt ggtgataaaa cagttggatt tgtaacaaca ggatgtgcat ctccaacaac
    10081 aggaaaaatt ttaggtatgg gaattataga ttctgagtat gcaaaagtag gaaatgaaat
    10141 aggtatagca atcagaaaaa aagttgttcc tgctgtgata gttaagaaac ctttttataa
    10201 aaaacaatat aaaaaagata atattatatt aaacaaagaa aataaatttt catatatacc
    10261 tgctacaagt gaagataaat caaaaatgtt aaaagtagtt ggattaaatt cagttgatga
    10321 attattttca gatataccag aagaagtaaa attaaaaaga gatttaaatt tggaaattgg
    10381 aaaatctgaa ttagaggtaa gcaaaatagt aaaaagattg tcagaagaaa atttaagttt
    10441 agaagacttg acttgttttc ttggtgctgg tgcatatgac cattatatac catcaattat
    10501 aaaacatata acttcaagat ctgaatttta tacagcatat accccatatc aagctgaaat
    10561 aagtcaggga actttacaag tagtttttga atttcaatct atgattgcag aaattacagg
    10621 tatggaaatt gcaaatgcat caatgtatga tggagcaact gctgcaatag aagcatgtat
    10681 aatggcaatg aatcagacta gaaaaagtaa aatagtagtg tcaaaaacta ttcatcctga
    10741 aactctgtca gtattaagaa cttacttaca atataaagat tgtgagatag tagaaattga
    10801 cttttgtaat gaatatggga ctacagatat agaaaaatta aaagcttctg tagacaaaga
    10861 tacagcatgt gttcttatac aaactcctaa tttctttgga attattgaag aaatggaaga
    10921 aatagaaaag ataactcatg aaaataaggc tatgttaatt atgagtgtag acccaatatc
    10981 attaggagtt ttaaaaacac caggtgagat aggtgcagat attgttgttg gagaagctca
    11041 atcacttgga aaccctctta attttggagg tccttatgta ggatttttag ctagcaaatc
    11101 taaatatact agaaaaatgc caggaagaat agttgggcaa agtttagatg tagaaggtaa
    11161 aattgcatat gtattaactt tacaaactag agaacagcat gtaagaagag aaaaagcaac
    11221 ttctaatata tgttcaaatc aagctttaaa tgctcttgta gcttcaatat atatggctac
    11281 tatgggtaaa gaaggattta aagaggttgg tatgcagtct atgaaaaaag cacattatac
    11341 ctacaataaa cttgtacaaa ctggaaaata taagccaata tttaaaggta agtttttcaa
    11401 agaatttgct gtacaaggaa atcttaatat agaaactata aatgataaac tcttagaaga
    11461 aaatatatta ggaggttata atttagaata caattatcca gaattaaaaa attcaacttt
    11521 gctttgtgtg actgagaaaa gaagcaaaga ggaaatagat aagttagttg gaataatgga
    11581 gggattataa tgaaagaata caatagtttg ttgatagata tatctaaaaa aggtaggaaa
    11641 gcatactcac ttccaaagtt agatatagat gatataaaaa tagaagatat gattgaccca
    11701 gatatggcaa gacaaagtga gttgaatttg ccagaagttg gtgaattaga attagttaga
    11761 cattatacat tattatcaaa taaaaacttt ggagttgata caggttttta tcctttgggt
    11821 tcttgtacta tgaaatataa tcctaaaata aatgaagata tggcagcact tccaaacttt
    11881 actggaatgc atccatacca atcttcggat acagctcaag gttctctttc tttgatgtat
    11941 gatttatcaa gaagacttgc agaaattaca ggtatggatg aagttacact acaaccttca
    12001 gcaggttctc atggtgagtt tacagggctt atgattataa aagcatatca tgaaaataga
    12061 ggtgaccata agagaaccaa agtgataatt ccagattctg cacatggaac aaatccagca
    12121 agtgcagcta tggcaaactt tgatgtgatt caaatagcat ctgataaaaa tggagctgta
    12181 gacataaatg cattaaaaga ggttttgaat gatgaagtag cagctcttat gcttactaat
    12241 ccaagtactc ttggtttatt tgaaaaaaat ataaaagaaa tagctactct tgtacatgaa
    12301 gcaggaggac ttttgtacta tgatggtgca aacatgaacg ctattatggg gataacaaga
    12361 cctggagata tggggtttga tgtggttcat cttaatcttc ataagacttt ttcaactcct
    12421 catggaggtg gaggtccagg agctggtcct gttggagtta aaaaagaatt agtacctttt
    12481 ttaccaatac cagtaattga aagaaaagaa gataagtatg tactaaatta tgatagagaa
    12541 aaatctattg ggaaaattaa aaatttctat ggtaattttg gagttcttgt aagatcttac
    12601 acatatatac taactatggg aagggatgga cttaaagagg ctagtgaaat ggcagtttta
    12661 aatgctaatt atataaagga aagtataaaa gatgattata ttttgccaat agataccttg
    12721 tgtaagcatg agtttgtatt aggtggattg ccaagaggag aggccaatat aaaaactatc
    12781 gatattgcaa aaagactact agattatgga taccatcctc caacaatgta ctttcctctt
    12841 attataaatg aggcacttat gatagaacct acagaaagtg agagtataga gacattagat
    12901 agttttatag aagctatgaa aagtgttgct aaagaggcaa aggaagaacc agaactattg
    12961 aaaactgctc cacataatac tttggtcaaa agagtagatg atgcaagggc agtaaagaaa
    13021 cctatactaa catggtcaca aagataaata gttaaaaagt agagatttaa agtataaaga
    13081 gaattaaatt tgtaagaaaa agctatctaa cttaatctag tttagatagc ttttttgtat
    13141 attagtatgt atggtatttt ctatataaag ttttaaattg tattagtgct tatatagaat
    13201 attgatatat tatgtataga tattaataag aattgttgaa tttatcttgc cttaacttta
    13261 tttactcttt tatattaaaa aaacttaact aaaatatagc gaaattcata a
//
LOCUS       DAEQAF010000100        13164 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.103, whole genome shotgun sequence.
ACCESSION   DAEQAF010000100 DAEQAF010000000
VERSION     DAEQAF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13164
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.103"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            87..1274
                     /locus_tag="KRN00_003035"
     CDS             87..1274
                     /locus_tag="KRN00_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBH1828887.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            1290..2873
                     /locus_tag="KRN00_003036"
     CDS             1290..2873
                     /locus_tag="KRN00_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBH1828888.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            2901..4229
                     /gene="ssnA"
                     /locus_tag="KRN00_003037"
     CDS             2901..4229
                     /gene="ssnA"
                     /locus_tag="KRN00_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBH1828889.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DPRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLVNIDEESILAKSRELSQNLWNRI"
     gene            4428..5780
                     /locus_tag="KRN00_003038"
     CDS             4428..5780
                     /locus_tag="KRN00_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBH1828890.1"
                     /translation="MSQDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVILNIFFNELGSKKEKNNKVEEAK
                     "
     gene            5972..7081
                     /locus_tag="KRN00_003039"
     CDS             5972..7081
                     /locus_tag="KRN00_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1828891.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            7364..8755
                     /gene="hydA"
                     /locus_tag="KRN00_003040"
     CDS             7364..8755
                     /gene="hydA"
                     /locus_tag="KRN00_003040"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBH1828892.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            8749..11310
                     /gene="xdh"
                     /locus_tag="KRN00_003041"
     CDS             8749..11310
                     /gene="xdh"
                     /locus_tag="KRN00_003041"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBH1828893.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETASLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSVPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            11462..12808
                     /gene="rpoN"
                     /locus_tag="KRN00_003042"
     CDS             11462..12808
                     /gene="rpoN"
                     /locus_tag="KRN00_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBH1828894.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
BASE COUNT         5232 a         1531 c         2693 g         3708 t
ORIGIN      
        1 gattaagtga aatgctaata aattaaaaaa gtgaaatatc aaaataaaac gtcaacaaat
       61 taaaaattat atgggggaat atcaaaatgt taaatgaaac aagaaaaaaa caattaactg
      121 aagtatgcca agacttaata agaaatgcta gttattcagg tcaagaagaa aacgtagtaa
      181 aagctataga agaaaatttt gctttactag gttttgatag ttggtcaaga gatagatatg
      241 gaaatatagt aggatgtata aaaggaaata aaccaggtaa aaaaatatta tttgacgggc
      301 atatagatac agttccagtt ccagatgcaa gtaaatggag tgttcctcct tttgaagcga
      361 gaatagtaga tgggaaaata tatggtagag gaacttctga tatgaagggg caagtaagtg
      421 ctatgatggc tgctgtttca tactttgcag aagatactaa caaagacttt gaaggtgaat
      481 tgtatgtagc aggtgttgtt catgaagaaa tatttgaagg tgtttcagct agagagataa
      541 gtaaggctgt tcaacctgat tatgttgtaa taggtgaatc ttcagaatta aacttaaaga
      601 taggtcaaag aggtagagga gaaatagtag tagaaacttt tggtaaacca gctcactctg
      661 ctaatccaga aaaaggtata aatgcagttt ataaaatggc taatgtaatc caaaagatac
      721 aacaattagt acctccaact catccagttt tgggtgatgg aatattagtt ttaacagata
      781 taaaatcttc tccatatcca ggagcatcag tagtgccaga ttattgcaaa gctacttttg
      841 atagaagatt attagttgga gaaacaagag aaggcgtatt agctccaata caagctttat
      901 tagatgaaat gatgaaagaa gacccagaat taaatgcaaa agtttcttat gcagttgaaa
      961 aagctgattg ctatacagga aatactatag aaagtgaaag attcttccca ggttggttat
     1021 atgacgaaga agatgaattt gttcaagcag cgtataaggg attaaaagaa gctggaatag
     1081 attcagaaat aactcaatac tcattctgta cgaatggaag tcactacgca ggtgaggctg
     1141 gaataagaac tataggattt ggtccttcta aggaaaatct tgctcataca atagatgagt
     1201 atatagaatt agaccaatta ttcaaaggtg cagaaggata ttatggtata ttaaaatcag
     1261 tttataaaaa ataattagga gatggttttg tgagaacttt aataaaacat gggcttatag
     1321 tagatggaaa taaaacacca gcatatgaag gagatatttt aatagaaaac gagaaaatat
     1381 taaaaatatc acaagattta aacgaagaag ctgacaaagt tatagatgca aaaggtagag
     1441 ttatatgtcc aggtttcata gatactcata gccattcaga cctagttatt ttagttaatc
     1501 catataatga ggtaaagatt agacagggaa ttacaacaga agtgttgggc caagatggta
     1561 tatctatggc ccctctacct caagagcata tatcttcttg gagaaaaaat ttagcaggtc
     1621 tagatggtga aagtgatgaa attgattgga aatatgaaac aacagagaat tatttaaaaa
     1681 tgatggatta caatggggta ggtttaaatg aaacttattt agtacctcat ggaaacgtta
     1741 gaatggaagc tatgggactt gaagatagac ctgctactaa agaagaaatt caaaaaatgt
     1801 gtgaaatcac agagagagaa ttaaaagcag gagctatagg attgtctact ggacttatat
     1861 atataccttg tgcatactca ttgactgaag aaattataga gatgtgtaag gtagtagcaa
     1921 aatatgatgg agtatttgta gttcaccaaa gaagtgaagc agatacaatt ttaacttcaa
     1981 tggaagaaat catagaaatt ggaaaacaat caggagtaaa agttcatttt tcacatttta
     2041 aggtttgtgg taaagcaaac tggaagtata taccacaagt tatagagctt ttagaaaaag
     2101 cagaaaagga aggaataaga gtatcttttg accaatatcc atatgcagca ggaagtacaa
     2161 tgcttggagt agttttacct ccttgggcac attctggagg aactgataag ttaatagaaa
     2221 gattaagtga tgaaaacgaa agagcaaaaa tgaaaaaaga tatagcaaat ggaatagaag
     2281 gctgggataa ttttatagaa tttgctggaa tagaccaaat atttgtaaca agcgtaaaaa
     2341 cagaaaagaa taaagataca attggtaaga gcttattaga aattggaaaa atgagaggaa
     2401 aagacccatt agatgcaacg tttgatttat taaaagaaga agaaaatgca gttgggatgg
     2461 tagatttcta tggattagaa gaacatataa taggattcat gaaaagagac gagcaaaatg
     2521 tgtgtacaga tggtctttta gcaggtaaac cacatccaag agcttatggt tctttcccta
     2581 aaatactagg aagatatgtt agagagttga atgtgttaac aatcgaagaa gctgtttata
     2641 aaatgactaa aaaggcagct acaagcttta gtataaaaga tagaggcgaa ttaaaagaag
     2701 gatattttgc agatatagtt atatttgaca aggatacagt tagtggttgt gatgatttta
     2761 tcaactctat gcagtaccct acaggtatag attacgtaat tataaatgga aattgtgttg
     2821 ttgaagaagg aaaatacaat aaaattaaag caggaaaagt acttaaaaat taaatcttag
     2881 ctttaaggag gaataaattt atgattttag tggggaatgg gaggctaata agccaagatt
     2941 ctttaaatcc ctatatggaa gatggatgtg tagtaataaa tgataatcta attgaagata
     3001 taggtactac agaagaaatg aaagctaaat atccagtaca tgaatttata gatgcaggca
     3061 agaaaataat catgccaggt ctaataaatt cacatatgca tatatacagc tcatttgcta
     3121 gaggaatggc agttccagga aaaccttctg agaacttttt agagatacta aacaatttat
     3181 ggtggagact tgacaaacag cttacactgg aagatacaaa atacagtgca tatgcaacgt
     3241 atatagaatg tataaaaaat ggtgtaacaa cagtttatga ccatcatgca agtccaaatg
     3301 caattgaagg cagtttgttt acaatatcag atgttgcaaa ggatttggga attagaacgt
     3361 gtctttgtta tgaagtgtct gatagagatg gtggaaatac aatccaacaa ggtatcaatg
     3421 aaaacgtaaa ctttataaaa tacgctcaaa aagatgatac agacatgata aaaggaatgt
     3481 ttgggcttca tgctgcattt acactatctg atgatacatt aaataaatgt gcttcagaga
     3541 tggctggtct tgatacaggt taccatgtac atgttgctga aggactagca gacttacaat
     3601 ataatgtaga taaatatgga aaaagggttt tagaaagatt caatgatttt ggagtactaa
     3661 aagaaaaaac aatagcagtt cattgtatat atataagtgc agaagaaatc agtcttttaa
     3721 ataaaacaaa tacatttgta gttcataatc cagaatctaa tatgggaaat gcagttggat
     3781 gttctcctgc aatagagtta ttgaaaaggg gagttacagt aggattagga actgatggat
     3841 atactagcga tatgtttgaa tcattaaaag ttgccaatat aattcacaaa catcacttaa
     3901 aagacccaag agttggattt gaagaatcac aaacaatgtt atttgataac aatagaaaaa
     3961 tagctaaagc ttattataaa aatgacctag gagtacttaa aaaaggtgct tatgcagatg
     4021 ttatagtagt tgattatata ccacatactc cattgacaga aaatacaata gggggacaca
     4081 ctatttttgg aatgagtgga agaagcgtag atacaactat tataaatgga aaagtactta
     4141 tgaaagatag aaagttagta aacatagacg aagaaagtat tttagctaaa agtagagaat
     4201 taagccaaaa tctatggaat agaatttaaa taattgatta tgcaaaattc tatgaagcag
     4261 gaaccctgtg actttagtca tgggaggttc agattaatat acaagtaaga aacaagagtt
     4321 tagatgttaa aaacagagct taaacaaaaa taggaattta aatgaagtat ataaataaaa
     4381 aatatacgga atagaatatt aaattaaata tagaagggag acccaaaatg tctcaagata
     4441 aaagccctaa aatagctcca gtagatgaaa ggttacctgt atccaaatct tgggtatttt
     4501 cactacagca cgttttagca atgtgtgcag gagcagtagc agttcctatg atgataggaa
     4561 gtgctgcacg actagatcat gctagtattg tttttttaat aaatgcttgc ttgtttatgg
     4621 caggtatagg aacactcata caaagtgttg gtataggaaa tattgtaggt gctaaaatac
     4681 cagtaataga aggaactagt tttgccgctg tggcaggtat gacagcaata gcctcatcat
     4741 atagtgattc acaagttgca atacagacgg tatttggctc tgtaatagta gctggattgt
     4801 tttgtatatt acttgctcca gtatttgaaa aattaataag atttttccct agtgtagtta
     4861 ctggaacagt tgttatggta ataggtattt cactatttcc agttgggata aaatggataa
     4921 ctgacaacaa attggaagcg gttgaaccaa actcattagc attagcttta gcagtattgg
     4981 caataacttt actttcattt aaattcttaa aaggaatttg gaatagcaca gctatattgg
     5041 taggtatagt acttggtaca ctactttcca tggcagttgg aatggcagat tttagtgcag
     5101 taaatggagt tggttggctt aacttaaatg tacctttaaa atttggaatg cctagatttg
     5161 aaccatctgc aatactatca ttgtgtttga ttatgttggt acttatgaca gaatcagttg
     5221 gtaatatgat agctattcat gaaatggtag acaaagaagt aacaggtaaa aatattaaaa
     5281 gaggtctatt tggagatgga atatctacag cattatctgg aatattcaat tcatttccaa
     5341 taactccatt tggtcaaaat acaggaatag taggtcttac aggtataaaa tcaagattta
     5401 tagcagttta cgcaggggtt atattgctag tacttggatt cttaccaaaa tttgcagcaa
     5461 taataggagc aatacctaag cctgttcttg gaggcgtagg atttgcaatg tttggaatgg
     5521 taatggttgg aggagtaaaa actttaagca aagtgaaatt tgatggaact aaaaatgggg
     5581 ttatagtagc agttagtgtt ggtttgtcta tgataccact aacaaatcct gatttctatc
     5641 ataatttccc aacttgggta caaacaatat tccatagtgg aataacaaca ggtagtttat
     5701 cagcagtgat tttaaacata ttcttcaatg aactaggttc taaaaaagaa aaaaataata
     5761 aagttgaaga agcaaaataa aaataaaaca agtaaaaatc tatattgact taaagtcatt
     5821 aagcattaat aaaaataatt cagagatatt aataattcaa caaaactatc ttatatttta
     5881 aataatataa aaaagtaaat aaataacgaa tacaaataaa agaatacaat ctaaatatta
     5941 aaaatattta atttaaggga gagataataa tatggctaat ttaaaagtta atttatatgg
     6001 gatggaattt ttaaacccaa ttatgacagc ggcaggacct ggagcaaaag atggtgctct
     6061 ctgtcaagag gcagcaaaag gtggagcagg agctatatgt acaaaaacta tatctgtatt
     6121 accagctgat gtaccaagac catgtatggc aaaaactaat agtggttttt taaacacaga
     6181 attatggtca gagcttccaa aagagcaatg gatagaggaa gaatacaaaa aggtaaaaga
     6241 aacagggctt ccagtaatag taagtatggg atattcagca gagcaaatag ctgaggttgc
     6301 tcctttagta aagccttatg cagatgcagt tgaattatct actcattatg taggtacaga
     6361 cgttgcacca atagtaaatg ctttaaaagc tgcaaaagct gttttagatg taccagtatt
     6421 tatgaaaatg agtcctcata ctgacattca aactattgca aaagctgttg aagaagcagg
     6481 tgcagatgga cttgtaatga taaactcatt tggaccatgt atggcaatag atgtaaatac
     6541 aggataccct ataatgggaa gtaaagctgg atacggatgg ttatcaggtg caccaataag
     6601 acctctagca ataagatgta tatatgaagc ttctcaagtt gtaaatatac caataatcgg
     6661 tgttggtgga atcacttgtg gaaaagacgt ggctgaaatg atgatggctg gagcaagtgc
     6721 tgttcaagta tgtacagaag caatccttaa agggccttct atctatggaa aaattgctaa
     6781 agaattaaat gaatttttag atgagaatgg atatgctgat gttaatgaaa taaaaggatt
     6841 aactcataag aaaatggcag ctagagggtt tagaactcat tcagtagctc cagtagtgga
     6901 tgataacaag tgtatcaaat gtaagcaatg tgtaacaagc tgtgtatacg aagctttaga
     6961 agttacagat aagttgaaca tagatgcaga caagtgtttt ggatgtggat tatgtgtaac
     7021 tagatgtcca aaaggagctt taagcatctg ctacaatcaa gtagaagcta tgaatgagta
     7081 ataattatat agaattttgg taattaactt agagtaatag gtattaggat aataaaatat
     7141 atcagataaa caaacacgca ttatgcatta ataatacagt ctaaagttaa taattttatt
     7201 atattgattt aactaaatat tagtttagct gaatattaat ttaattaggt attggtttaa
     7261 tcttaatata gatttactgc gtataagtga actaactaga ttactttaag ttaatttttt
     7321 catataaaat aaattgatac attacaagta aggtggagtc tatatgggaa ttgttttaaa
     7381 aggtgggaaa gtagtaacaa gtgaaaaaac ttactgtgca gatgtaagaa tagaagatga
     7441 aaaaatagtc gatataggtc ttgatatatc aaaagaaaat gatgaaatag ttgatgttag
     7501 tgattcttat gttataccag gaggtataga tacacacaca cactttgact tagatacagg
     7561 cgttactaag acagcagata actttgagac aggaacaaaa gctgctatag taggaggaac
     7621 tactactata ttggattttg ctacacaagc taaaggatgt tctttgaaag acggattaga
     7681 agaatggcat gaaaaagcta aggataaatc ctattcagat tatggctttc atatggctat
     7741 aacagattgg aatgactcgg tttgtaatga aatggaggat atggtgaaag agggagtatc
     7801 ttcatttaaa ctgtatatgg cgtataaagg aagccttcaa gttgatgatg gtgtaatctt
     7861 tgaagcattg agaaaagcag aagagatagg agggattatt ggtttccatt gtgaaaatgg
     7921 ggacataata tgtgaacttg tggataaagc aaagtcagaa aataatttat ctccaaaata
     7981 tcatcaatta actagaccag ctataatgga ggcagaagct acatcaagac ttatgaagat
     8041 agctgaagtt gcaaactcta aagtatatgt agttcactta agctgtaaag aatccttaga
     8101 ggaggtttta aaagctaagc aaagaggtgt ggatgtaata gttgaaactt gtcctcaata
     8161 ccttctatta aatgatgaat tatatgattt agatggattt gaaagtgcta agtatgtaat
     8221 gtcaccacct ttaagaaata aagaaaataa tgaaatatta tggaatgcta ttttagataa
     8281 tcaaatagac actataggaa cagaccattg ttcttttaat tataagggac agaaggaact
     8341 tgggataaac gatttcagta agataccaaa tggttctcca ggtgtagaac ataggatgag
     8401 tcttttatac acatatggag tctgtaaaaa taaaatatct atcaacaaga tggtagaagt
     8461 aacatcaact aatgcagcaa agttgtttgg aatgtatcct aataaaggaa ctatagaaat
     8521 aggcagtgat gcagatatat tagtcttaaa tccaaacaaa aaatccaaaa tagaagcgaa
     8581 aaaacaatta caaaatgtag attatacacc ttatgaaggg tatgaagtgg attgtcaaat
     8641 agaacatgtt tatttaagag gaaaagaagt agttagagat ggagaattaa tctgtaatac
     8701 tccaagtggg agatatataa ataggcgtct aacaaagggg gctagagaat ggtagaattt
     8761 atattaaatg gagagaaagt tgttgcaaaa gaaggcaaaa aacttttaga cttccttaga
     8821 gaagatatga atataacttc agttaaaaat ggatgttcag aaggtgcttg tggaacatgt
     8881 atggttataa tagatggtaa agctactaaa gcatgtgtat ttaaaactga taaattagct
     8941 gggaaaaaca taacaactat agagggatta tcagagagag aaagagatgt ttttgcatat
     9001 tcttttgcta gtcaaggagc tgtacaatgt ggattttgta ttccaggtat ggtaattagt
     9061 tcaaaagcac ttatagacgt taataataat cctactgaag atgatataaa gaaagcttta
     9121 aaaggtaata tatgtagatg tacagggtat gtaaaaataa ttaaagctgt cgatttagca
     9181 gcaaagattt ttagagaaaa tatagatgtg ccaaaagtaa actgtaaggg tttagtaggt
     9241 gaaaatcttc ctagagttga tgcagttggc aaagcacttg gatattctga atatgtagat
     9301 gatatgagaa ttgagggtat gatttatggt tcagcagtta gagctaagta tcctagagct
     9361 ttagttaaaa aaatagatat agaagaagca aaagcttatc caggagttgt tgcagttcta
     9421 acagctaaag atattccagg aactataaag gtagggcact taaagaagga ttgggatact
     9481 ttaataccag aaggtgaaat aactagatac ttaggagatg gaatagtttt agtagcagca
     9541 gaaactagag aagcgttaga agaggccaaa aagctagtta agatagatta tgaggaatta
     9601 acaccattaa gtactacagc agatgcactt agagaagatg ctccaaagat acatgagaca
     9661 gggaatatac ttgttaagga acatttagta agaggaaacg ctaaagaaaa gatagaaaat
     9721 tcaaaatatg ttgtaactaa aagatatact acacctgcta cagaacacgc atttttagag
     9781 cctgaatgtg cagtagctgg tccttatgaa gatgatggag taataatcta ttcaacagac
     9841 caaggggtgt ttgccactca acatgaatgt gcagatatgt tagggttacc atatgagaag
     9901 gtaagagtta taaacaaaat ggtaggagga gggtttggtg gaaaagaaga catgagtgtt
     9961 caacaccatg cagccttact tgcataccat acaaagagat ttgtaaaagt acagttaaca
    10021 agaaaagaaa gtattattgt tcatccaaaa cgacatgcca cagaaatgga atttacgaca
    10081 gcatgtgatg aaaatggata cttaacgggt atgaaggcaa cgataatatc tgacacaggt
    10141 gcatatgcct ctcttggagg accagtgcta caaagactgt gtactcatgc agcaggacca
    10201 tacaattatc aagatattga tataacagga acagcagtat atactaataa ccctcctgga
    10261 ggagcattta gaggatttgg agttacacag agttgttttg caactgaatg taatctaaat
    10321 ttacttgctg aaatggttgg aatatctcct tgggagataa gatataaaaa tgcaataaga
    10381 cctgggcaag ttttaccaaa tggtcaattt gcagatgaag gaacagcaat ggcagagaca
    10441 ctagaagctg taaaagaaga gtatgaaaag catccacgtg caggtatagc ttgtgctatg
    10501 aaaaatagtg gggttggagt tggtatacct gatgttggaa gatgtagatt ggtgataaaa
    10561 gatggcaaag ttcacataag aacaagtgct tcttgtatag gtcaagggct tggtactgtt
    10621 atgactcaag tagtttgtga aactgctagc ctacttcctg aaaatatagt gcatgaagtt
    10681 ccagatactc atttaacacc agactctggt aatactacgg cttcaagaca gacagtattt
    10741 acgggagaag ctactaaggt tgcatcaaat aagttaaaag aagctttaga ctctggcaaa
    10801 actttacttg atttagaggg agaagagttt tatggagaat atgaaagtat tacagataaa
    10861 atgggttgtg acaaagaaaa tccagtaagt catgttgctt atggatatgc aacacaagtt
    10921 gtaattctgg atgaaaatgg aaaactagaa aaagtagtag cagcacatga tgttggaaga
    10981 gctataaatc caatcagttt agaaggtcaa atagaaggtg gagtagttat gggtcttgga
    11041 tatgctctaa ccgaagatta cccagtagtc aactctgttc ctacagctaa gtttggtaca
    11101 ttaggtttat ttaaatctac agatatacca gaaatacaag ctttaatagt tgaaaagaac
    11161 aaagatttat tggcttatgg ggcaaaaggt gtaggagaaa tttgtacagt tcctactgca
    11221 ccagcagtac aaaatgccta ttatgtattt gataaagaat ttagaactga gctaccacta
    11281 caaaatactc catatagtaa aaaaaagtaa caaaaaaaag aaatattaaa taaaaaaata
    11341 gatgaaattg taaataaaaa aaaccctttt gcataaggta tattttaaat gatagaatat
    11401 acatatacag gagggttttt cttttataaa ataagtttaa taaaattgag aggtgagcag
    11461 aatgaatttt aataatagtc tagaattaac tcagtctcag aagctaataa tgactacaca
    11521 acttaagcaa tcattatcaa tattaaatat gagtaagtta gagttagaag aagagataaa
    11581 aagagaagca gagaataacc cattagttga agtcgagaaa agtggggaga taaattggga
    11641 agagtatata aaagacatgg ataggtcaag acgtttagat agaacagaga taagctataa
    11701 tcctgataat gaagttaatc tagaaaattt agttaaatat tcgtcaaatt tatatgaaga
    11761 tttaaaattt cagataagcc tgtataaact tacagacaaa gaattggaag tctgtgagta
    11821 tataattgat agtttagatg aggatggata tttaagaact gaggaaaaag taattgttga
    11881 taccttaaag atagatgaag aactttttga aaaatgttta attagtgttc agcagttgga
    11941 acctagtgga gtaggggcaa gaagtctttc agaatgtctg atgatacaaa tggctagttt
    12001 aggaatatat aatgaaattt tagaggaaat cgttacaaaa gacttaaatt taattgcaaa
    12061 taataaatat aaagagataa gtaaaaagta caatatgtca ttacaaaaat gtgttgaact
    12121 aataaacata attaagacat tagaccccaa accaggaaga acttgttcag tagagaaaag
    12181 tgtatacatt caacctgatg taacagtaga aaaaattgat gatgaattta ttgtatattt
    12241 aaatgagaaa gattcttatc aaataagaat caatagttat tataaagaca tattaaaaaa
    12301 ttcacagtct gatgaaagtg caaaagaatt tataaaagaa agactaaatt cagcaacagg
    12361 acttatgaaa aatatagaga gtaggaaaac tacagtactt aagattgcag aagagatagt
    12421 aaaagctcaa gatgaatttt tgagaaaagg gacaaaatat ataaaacctt tgaaaatgaa
    12481 agacatagca gaaaaattag aatttcatga atctactata agtagaggtg taaatggtaa
    12541 atatatgcta acaccttttg gcgtatatga atttaggtac tttttcagta gcgccattga
    12601 gactgagaat aatgaaatgg catctagtac aagcataaaa aaaattataa aggaaacaat
    12661 aaaagacgaa aataaaaaga aacctttaag tgatgaccat atatctaagt tattaaaaga
    12721 aaaaggaatc aatgttgcaa gaaggacagt tgccaaatat cgtgaagaat taggaatccc
    12781 atcttcaagt aagagaaaag aatactaata agtaaaagac aaatatcagt atggtaaggg
    12841 gaaaaggcta attaagagat gaatgtagat tgggctaaaa attttataaa gtaaaataat
    12901 agaatatgga aaagtattaa aatgctataa ggtattaaaa aactggggaa cattaaaaca
    12961 ttaagatagc aaagagcata aaaaactaaa gaagattaaa acattaaaga acattagagc
    13021 tttgaggaat attagaactt taaagaatat taaaatttat aaaatataaa aatactaaaa
    13081 agaattgaaa aactggggaa cattaaaata ttgtaaaatg ctaaaaaact agaaaacata
    13141 attaaataag tgcttataaa gaat
//
LOCUS       DAEQAF010000101        13062 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.104, whole genome shotgun sequence.
ACCESSION   DAEQAF010000101 DAEQAF010000000
VERSION     DAEQAF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13062
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.104"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            33..497
                     /gene="bcp"
                     /locus_tag="KRN00_003043"
     CDS             33..497
                     /gene="bcp"
                     /locus_tag="KRN00_003043"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBH1828895.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            507..1250
                     /gene="yaaA"
                     /locus_tag="KRN00_003044"
     CDS             507..1250
                     /gene="yaaA"
                     /locus_tag="KRN00_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBH1828896.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFGIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLQVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFDLEGYKYKENLSNNSEYIFVKE"
     gene            1378..4035
                     /locus_tag="KRN00_003045"
     CDS             1378..4035
                     /locus_tag="KRN00_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBH1828897.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVVGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTISPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      4089..4191
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            4301..5566
                     /locus_tag="KRN00_003046"
     CDS             4301..5566
                     /locus_tag="KRN00_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBH1828898.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            5596..6486
                     /gene="metA"
                     /locus_tag="KRN00_003047"
     CDS             5596..6486
                     /gene="metA"
                     /locus_tag="KRN00_003047"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBH1828899.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            6977..7420
                     /locus_tag="KRN00_003048"
     CDS             6977..7420
                     /locus_tag="KRN00_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1828900.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            7451..9268
                     /gene="ftsH"
                     /locus_tag="KRN00_003049"
     CDS             7451..9268
                     /gene="ftsH"
                     /locus_tag="KRN00_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBH1828901.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            9446..12148
                     /locus_tag="KRN00_003050"
     CDS             9446..12148
                     /locus_tag="KRN00_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBH1828902.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALERK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            12182..12880
                     /locus_tag="KRN00_003051"
     CDS             12182..12880
                     /locus_tag="KRN00_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828903.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKEIWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
BASE COUNT         5119 a         1506 c         2396 g         4041 t
ORIGIN      
        1 aattattaat aaaaacaaaa ggagagatat ttatgttgag tataggaaca aaagcaccag
       61 aatttacact agaagataaa gatggaaata aggtaagtat gtcagatttt aaaggtaaaa
      121 aagtagtagt atatttttat cctaaagata atacaccagg atgtacacgt caagcttgtg
      181 cttttagaaa tgcatatgat ggatttaaaa aggaagatat acaagttatt gggataagta
      241 aagatagtat aaaatcacat caaaaatttg cagaaaagca tgaacttcct tttattttac
      301 tttctgaccc tgacttagtt gctataaaag cttttgatgt atggaaagag aaaaaaatgt
      361 atggaaaaac tgcattggga gttgtacgtg cgacatatat tatagatgaa aatggaatta
      421 ttgaaaaagt ctttgaaaaa gcaaaaccag acacaaatgc acaagagatt cttgaatatt
      481 tggaaaaaca ggagtaataa gaatttatga ttataatgtt atcaccagct aaaaatatga
      541 agaatataga agtatttgat agagatttga gtttgccttg ctttatagat aacacaaaag
      601 aaatagtgga aaatataaag acatttggta tagaagattt taaaaataaa atgaaaatta
      661 atgaaaaatt agctgtatta aataaaaata gatttgaaag cattaaattt gatagattag
      721 gaaaccctgc aatcttaact tatgatggaa tacaatataa aaatatagaa gcagaaaatt
      781 ttacaaggaa agatgaagag tttgcaaata gctgtattcg aatcataagt ggattgtatg
      841 gtgttgtaaa accatatgat agtatatatg aatatagatt agaaatgcag acaaaattac
      901 aagtaggtga gtttaagaat ttatacgaat attggggaaa tcgtatatat aaagaactaa
      961 tcaaagaaaa aacagctatc gttaatcttt catcaaatga atacagcaaa tccatagaaa
     1021 aatttattaa agatagtgat acatatatta catgtacttt taaagtaaat aaaaatggca
     1081 tattgaaagt ggaatctaca caagcaaaga aagctagagg tatgatgaca aaatacattg
     1141 taaaaaatag gataagagat attgaagaac tgaaaaagtt tgatttagaa ggttataagt
     1201 ataaagaaaa cttatctaac aatagtgaat acatatttgt aaaagagtag aagttttgtt
     1261 aaatattaaa tggcattgtt aaatttaggt aaaatatact tagtgtgtat tgaattgaac
     1321 ttgattttaa aatataatta ttcttaaatt aaaaaaagaa aggagtggtc ttccaaaatg
     1381 gaaaatcaca aacagatgcc ttggcattca agagcaacgc atgaaatttt agaaagtcta
     1441 gattcatcag aggaggggct caccgatacc gaggcggaaa aacggcttaa agagaatggc
     1501 ttaaatgaac ttagaaaaaa accacctaga acaactttac aaatgctttg gagtcaaatt
     1561 acagatgcta tggttatgat actaatagga gcagcaatat tatctttgat atttggcgaa
     1621 tttacagaag cttttgtaat actaataatt gtaacagtaa atgcagttat tggaattgtt
     1681 caagagaaaa aagcagaatc atcattagaa gcattaaaaa atatgaattc acctacagct
     1741 cgtgttatgc gtgatggtga agaaaatgtt attccagcaa gtaatcttgt agtaggagat
     1801 attgtttttt tagaagatgg agctatggtt ccagcagacc ttcgtttaat agaaacatca
     1861 agtttaaaaa ttcaagaggc ttctttaaca ggagaatctg ttccatcaga aaaagatgca
     1921 gatacaatct cacctaaaga atgtgtatta ggagaccgta gcaatatggc gtatacatct
     1981 tcaatagtca catatggtag aggtgtaggt gttgtagtag caactggtat ggatacagaa
     2041 gtgggtaaca tagcacatct tttagattca caagatgatt ttgatactcc tataaaacgt
     2101 aaacttaata ctgttggaaa gacattaagt gtcataggta ttattgtatg cgttgttata
     2161 tttgcaatag gtgcatttta tcagagacct ctcttgccaa tgtttatgat tgcaatttcc
     2221 cttgccatat caattattcc agagggatta cctgcaacag ctactattgt aatggcttta
     2281 ggcgtacagc gtatggctaa aagaaatgct ttaattagaa aattacctgc tgttgaaaca
     2341 ttaggaggag ctacagtaat atgttgtgat aaaactggta cgttaacctt aaataaaatg
     2401 actgttacac atattgctgt caatggagat tttgaatctg gaaaagtgac atcaatagat
     2461 actgcatctg aaaaacatcc attagtgtat aaagagattg tttatgctgg tgcactttgt
     2521 aatgatgcat gtattaatcc agataaaaca gatgaaatat taggtgaccc aacagagggc
     2581 gcattaattt ttatggccaa aaaatttgga atagatcaag aagctcttga agaagaatat
     2641 ccacgtgtat ttgaacagcc ttttgattca gatagaaaat gtatgacaac tgttcataat
     2701 atagatgaaa agattattgc ttatactaaa ggagcagtag acgaaattct tgacctatgt
     2761 actaaaatat taacttcaaa aggtgaaaga aacattactg aagtggataa aaagaatata
     2821 cacgaattat gtcttaacat gtctaaagat gcattgcgtg tacttggttt tgctaagcgt
     2881 gagatttcat ctataccaaa agaagatagt gaaaatatag aatatgattt aacatttata
     2941 ggtatggttg gtatgattga cccaccaaga actgaggtaa ttgatgcagt aagtacttgt
     3001 aaagaagcag gtataagaac cataatgata acaggtgacc ataaagttac tgccacaaca
     3061 atcgctcatg agttaggaat atggagtgaa gaaaatactg tgatatctgg tgatgaactt
     3121 gataatttga gtgatgatga actagatgaa gctgttaaaa atactacagt atttgctcgt
     3181 gtatccccat ttgataaact tagaattata caatctctaa aaagaattgg agaagtacca
     3241 gcaatgactg gggatggtgt aaatgactct cctgccttaa agtctgctga tattggtata
     3301 gccatgggta taagtggtac agatgttgca aaagattctt ctgacatgat tttaatggac
     3361 gatagtttta caacaattgc ttatgcaata aaagaaggta gacgtgtata tagaaacata
     3421 caaaaagtta tacaattttt gcttgttggt aatatagcag agatacttac gttgtttgta
     3481 gcaatattat taaattggga tactccgctt cttgctgttc atattttatg ggtaaacctt
     3541 gcaactgcta cgcttccagc ccttgctctt ggagttgacc caccaagcag aaatataatg
     3601 aagcaccagc cagtgaaatc aaccactttg tttgaaaaaa atcttataca aagagttgtt
     3661 acccaaggta tatttgtggc aataatgact attttagcat ataaaattgg tcttaatata
     3721 gaaaatcatt ctgtaggtca aacaatggca ttttgtgtat tagcattttc acagatgtta
     3781 cgagcattta gtcagcgttc aaatacagat tcaatgttta atagaaataa tggtaaaaat
     3841 ccatttcttt taatctcatt tttaacttct gcatttttaa tagcagtaat actgtttgta
     3901 cctgttttta gaaatgcttt taacttaaca gttttaaata acttagagtg gcttataacg
     3961 attgttttag ccataatgtc tgtaattcaa gtagaggttg ggaaaattat taaaagaaaa
     4021 aaattaaaaa aatagttgac aaaattagga aaaatatata agatataaaa catagaaaaa
     4081 ttaaataaat cttatccaga gaggtggagg gactggccct atgaaacccg gcaaccagta
     4141 tatttatata cattggtgct aaatcctgcg gcgaaagctg agagatgagt ataattaagc
     4201 ttatacagag cctgagttat atactcaggc tttatttatt ttaactctca tctggtaaat
     4261 agtttaattt tttttactaa aatctaaggg ggatacaaga atgtataata aagaaacaat
     4321 atgtgtgcaa ggaaattata aaccaggtaa tggagaacca agagtactac ctttatatca
     4381 aagtacaact tttaaatata gcagtataga ccaacttgct gaattatttg atttaaaagt
     4441 tgatggacat atatattcaa gaataagcaa tcctactatt caagcttttg aagaaaaaat
     4501 aagtttacta gagggtggag tatcttctgt agctgtatca tcagggcaat ctgcaaatat
     4561 gttggcagtt ttaaatatat gtaaatcagg agatagtata ctttgttctt caaaagtata
     4621 tggaggaaca ttcaatttac taggacctag tcttaaaaaa tttggtatag atttaatatc
     4681 gtttgactta gattcaagtg aagatgagat agtagaactt gcaaaggaaa atactaaggt
     4741 tgtgtttgca gaaacacttg caaatccaac tcttgaagtc atagattttg aaaaaatagc
     4801 aaatgtagct aagagaatta atgttccatt tattgttgat aattcattag catctccagt
     4861 gctttgtaac cctttaaagt atggagcaaa tatagttact cattctacca caaaatattt
     4921 agatgggcat gcttcaagtg ttggaggaat tatagtggat ggtggaaact ttaactggga
     4981 taatggaaaa tttccagaat tagttgagcc agacccaaca tatcatggta taagctatac
     5041 tcaaaaattt ggaaatgccg catatgcaac taaagcaaga gttcagttgc ttagagacta
     5101 tggaaattgt ttaagcccat tcaatgcgta tcttactaat ttaaatgttg aaacactaca
     5161 tcttagaatg gagagacata gtgaaaatgc acttaaaata gctagatttt tagaaaaaca
     5221 tgaaaatgta gattggatta attacccagg acttgaagat aacaagtatt atgagaatgc
     5281 caaaaagtat ttatcaagag gatgtagtgg tgttttatca tttggagtaa gaggtgggtt
     5341 agaaaatgcc aaaaaatttg tggaaaaatt acagatagca tctttggtta cacatgtttc
     5401 agatgtaaga acttgtgtta tacatccagc ttcaactact catagacaat taacagaaga
     5461 acaattaatt gcatctggag tattgccttc actaataaga ttatctgttg gaatagaaaa
     5521 tgtagaggat ttaatagctg atttaaatca agctttaaat ttctaatatt ctaagagaaa
     5581 gagaagtgaa aagatatggc tttaatacta ccaaagggat tacctgttat taataaatta
     5641 ttagatgaag gaatagatgt aatttataaa gaagatttta aaaaggaatt aaagtatgaa
     5701 gaaaacatag acactaagat agctatacta aatctaatgc ctataaagat agatacagaa
     5761 ttagatttac taagaaggat agataaaaca ggattcaacg tgtctgtgga atttattaaa
     5821 atttcaacaa gagaaagtaa aagaagttgt aatgaatatg ttaaagaatt ttataaaaca
     5881 tttgatgaag ccaaaggaga gtattttgat ggctttataa taacaggagc tccagttgaa
     5941 caaatggagt ttgaagaagt tgattattgg aatgaactag aagaaattat ggattattct
     6001 aagagaaaaa ctaaatctac attatatata tgttgggcag ctcaagcaag tctttacaaa
     6061 tactacaatg taaaaaaact tccactaagt caaaaatgtt ttggagtatt taagcataag
     6121 gtagataaag atagtaaaat agtagatgga tttgaaaatg aattttttgc tccacattca
     6181 agacatacta ctgtaaatat tgaagctttg aaagagaata aagagttgag cattgtgagt
     6241 cattctaaag aagctggtcc ctatataatt acaaattcaa gagatgtgtt cgtaatgggt
     6301 catagcgagt atgacaaata cactcttgat aaagaatata agagggatat aaataaagga
     6361 gataaaatat ctatacctca aaattactat attaatgatg acccttcaga agagccaact
     6421 gtaaaatgga aaaaacattc agaattgttg tttagaaatt ggataaaaaa ctatttgata
     6481 caataaattt taagagtata taaatgttaa ctaaaaaaat atagaaattt ataggtataa
     6541 agttaatctt aatgatactt tataccttat ttttttaaaa tttgacctta taatagtagt
     6601 tttatatttt aagaaaatca ctttaggtgt atgtagatag aggtggcttt aattttatat
     6661 atggtgcgat aatgggagac taaaccttta tagtatcaat aaatttgtat tttaactttt
     6721 aaaagagatt aaaaagggag aaatcagtgt aaaatatata tatagatttt ttattaaatt
     6781 ttattaaaaa tatcctgtat aaaattaaat atcaataaga taacaaaatt tcaattgaag
     6841 ttacaatatt gtaattgaca ataaatactt aatactataa tatttaatac attaaacatt
     6901 atagtgttaa gtatttattt acagtatgca cttcagccta aatttgaaat aaagtatttt
     6961 cgtagggagc gtttgtatgg atgagatgag ttttaagaaa gagctactag agttgactag
     7021 agatataaat atgaaattta caactttatt aagtgatttt tatcagccac ttggtattac
     7081 agcagtgcaa gctttgattt tatctgagtt atgtgaacat ggagagaaaa aaataagcga
     7141 tttagggaag aacttaaaca tgacaaatag taatgtatca gtaatctgtc aaaggcttga
     7201 aaaaaatggc tttttaaatc gcataagaga tatagaagac caacgaattg taaaagtaaa
     7261 agttacaaat aaatcattgg atatacaaga acatatttca agtagtattt ttgatagtta
     7321 ttttgaaaat atgaccagtg aaaaattgca agatatggaa gatataatag aaggtttaga
     7381 gaaattaaat aaacttttaa cttacattga ttgcaaataa cataaaaata atttaaagga
     7441 gaataaaatt atggatgaac ataaacccca aaaaaggtca gcactctatt attatacagt
     7501 tataataata gtagtaatgt ttttaaatgc tttaatattt ccaagtttaa tggataaaaa
     7561 aatggttgag attgactatg gaaagtttct cacaatgttg gatacaggaa aggttaaatc
     7621 tgttgagata gaaaataata gaatagcaat aaatccatct agtagcaagg ataagaatat
     7681 atacataact ggtagaatgg atgacccaga attggtagat agactaaaaa atgcaaaagt
     7741 agaatttact aaggttattc ctaaggaaaa ttcacctctt ttaagtattt tacttacatg
     7801 gataatacct ataggtattc ttatgctatt tggtaactta atgatgaagt ctatgcaaaa
     7861 gcgaatgggt ggtaatgcta tgcaatttgg aaaaagcaac gccaaaatgt atgtatctgc
     7921 tcaaagtgga aaaagattta atgatgtagc tggtcaagat gaggcaaaag aagctttaac
     7981 tgaaatagta gatttcttac acaatccaga aaagtataaa aagataggag cacaaatgcc
     8041 taaaggagca cttttagtag gacctccagg tacaggaaaa acactccttg caaaagctgt
     8101 agcaggtgaa gcaaatgtac catttttctc aatatctggt tctgagtttg ttgagatgtt
     8161 tgtaggaatg ggagcttcta ggattcgtga tttatttaaa caagcaaaag aaaaagctcc
     8221 atgtatagtg tttatagatg agattgatac tattggtaaa aagcgtgata atggaagtgg
     8281 attaggtgga aatgatgaac gtgaacaaac tttaaatcag ttgttaagtg agatggatgg
     8341 ttttgatggt ggaattggag tagtaatact tgctgctaca aatagacctg acagtcttga
     8401 caaagcatta cttcgtccag gaagatttga tagacgtata ccagttgaac ttccagacct
     8461 tggaggacgt gaagctatat taaaggtaca tgctcaaaat gtaaatgtaa gctcagatat
     8521 agattataat gcaattgcaa ggtctacatc aggagcatca ggtgcagaac ttgcaaatat
     8581 tgtaaacgaa gcagcacttt tagcagttaa gtctggcaga gatatagtag aacaacagga
     8641 ttttgatgaa tctgttgaaa ctgtaattgc tgggtatcaa cgtaaaggag ctgtaatttc
     8701 agataaggaa aagaaaatta tagcatatca tgaaataggt catgcacttg ttgctgctat
     8761 gcaaaaacat tctgcacctg tccataagat tactataata cctagaactt caggagcatt
     8821 gggatatact atgcaagttg ctgaagatga gagtgtactt atgtctaaag aagaagcaat
     8881 tgataaaata actactttta caggtggtcg tgctgctgaa gaggttatct ttaacacttg
     8941 tacatcagga gcatcaaatg atatagaaca agctactaaa attgcaagag ctatggttac
     9001 tcgccttggt atgagtgaag agtttgatat ggtcgctctt gaaactgtaa gcaatcaata
     9061 tttaggagga gatacttctc ttgcttgttc ttccgacact gctgctaaaa tagatgaaga
     9121 ggtatttaaa atagtaaagg cttgtcacaa aaatgcaatt gaaatcttag aaaataatat
     9181 tgataaattg catgaacttg ctaattattt attagaaaaa gaaactatta caggtgatga
     9241 gtttatggaa atacttaact taaactaaaa tgattataca caagataaaa atgcctattg
     9301 ttaggcattt ttattttaca actaaatttt ttaaattcat atttaaatct ttacataatc
     9361 ttaatcatta aaaatacatc ttaactacaa ttttatatcg gaattgatat tataatagta
     9421 atgaatggtg taaggaggtt ttttaatgga tagacctaat cctgatattc tattagaaaa
     9481 aattaaaaat gaagaagaaa aactaagtag aggtcaatta aaaatattct ttggttatgc
     9541 agctggagta ggaaaaacct actctatgtt ggaatctgca caaaatttaa aaaaagtggg
     9601 tgtggatgta gtagttggat atattgaacc acacactaga ccagaaacat tggctttact
     9661 tgatggcttg gaaattcttc ctgtaaagga gatagaatat aaatctataa aactaaaaga
     9721 atttgattta gatgctgctt tagaaagaaa accagaagtt atattagtag atgaatttgc
     9781 ccattctaat gttgctgggt taaggcatac aaaaagatgg caagatatag aagaattgct
     9841 gttagcaggc ataaatgtct acactactgt aaatgtacaa catttagaaa gtctaaatga
     9901 cattgttgag ataattacaa acgtatcagt taaagagact ataccagata agtttttgga
     9961 tacaaataca cagttagaac ttatagatgt tgaacctgat gtacttcttg aaaggttcaa
    10021 tgaaggtaag atatataaga aagaacaagc tactagagca aaaaataatt tttttataaa
    10081 agataacctg gttgcactta gagaaattgc acttagaaaa acagcagaga gagttaataa
    10141 agaagttcaa atgaccagac tatcaaaggg tgatgtaact gtaataccta catcagatac
    10201 acttcttgca tgtataagtc catctccatc ttcagcaaaa gttattagaa ctgcatccag
    10261 aatatcagac agtacatttg caaaatggat agctttatat gttgaaactc caaacacagc
    10321 aagacttcca tttgatgaac aaaaacaact acaaaataac ctaaaattag ctaagaaatt
    10381 aggtggagaa ataattgttt tacatggtga aaatataata gagcaaatac ttagaattgc
    10441 aaagctgaga aatgtaacaa aaattgtaat aggtagaaat cattcaagta ataaaagatt
    10501 tagtaaaaga tttaaaaaag atatagttga caaattaatt gatgaagttg attatataga
    10561 tatacatata attccatata aatttgcctc agatgttaaa tacaaaccta aaaaggataa
    10621 atcatcaata aaatctaaat ttaaaattag caaagttgat tttataaaac ttatatttat
    10681 tactttgatg ataagtattt tagcatatgc agtacaaagc atgggattta taagagaaaa
    10741 tatattgtta atatatatgt tgggtgtagt tttagtttct atgtggacta aagggtatag
    10801 tacaggcata ataagttctg tatttaatat agttctttta aattattttt ttacagcacc
    10861 attatataca ttatctatag cagattcaaa ctatatagta acactggttg tattctcaat
    10921 agtaggtata ataactagca ctcttacgtc taagatacag catgaagcag aaactgctgc
    10981 taaaagagaa gaaaatacaa aaatgatata tcaaataatt aagggatttt taagattatc
    11041 aaataaagat gatatagtaa acaaaggtat agaacttttg tctcttagct taagtagaga
    11101 tgtaatttgt tatttaaatg tagataagca taataaatca aagctttaca aaaaaaatac
    11161 taataataag gataaaaatg atttggatag tgaagatgaa aaagctgttg caagttgggt
    11221 tttatccaat tcaacagtgg caggaaatga cacggataca cttcctggtt caaagggata
    11281 ctatatacca attgtaggaa tgaatttaac tttaggagta gtgggaatat catgtattga
    11341 ttcgaaattg gatacagaag atataagctt aattgaaaca ataattgctc aaatggcaat
    11401 agcgcttgat agagaaatct tgtcagaagc taaagaaaat accaatcttg agattgaaag
    11461 ggaaagatta agaagtaatc ttttaagagc agtttcgcat gaccttagaa ctccactagc
    11521 aggaatatct ggtgcagtaa gtacaattat aaaaaacaag ggtactatag gtcaagatat
    11581 aatagatgaa ttacttagtg gtgtatatga agatactcag tggttaataa gacttgttga
    11641 aaatttactt agtatgacca agatagatga agggaaattg gaagttaaaa aacattctga
    11701 actggttgag gaaattatat cagaagcgtt acaaaaaata aaaaaaagaa ttgaaaatgc
    11761 acttatagat attaatatac cagaacagat attatttgtt cctatggatg caaaattaat
    11821 agaacaagtt ttaattaatt taatagataa ttctttgaaa tattcaaagg aagattgtaa
    11881 gatagagata aatgtatatg agaaagatga ttatgtttgg tttgaagtat ctgataatgg
    11941 tcctggtata tcaaaggaac ttaaaaagca tatctttgac agatttttta ctggagaaga
    12001 aggagctaaa gattccagaa agggtgttgg acttggatta tcaatttgta aatctataat
    12061 tcaagctcat aaaggtgaaa ttatggtaga aaacaataaa gataagggtt caacttttaa
    12121 gtttagtttg cctaaggaaa atgaatagtt ttaaatttta aaattagttt tggaggaaga
    12181 aatgagtaaa aaacttatat tgttagtaga ggatgataag acaataagaa aatttatatc
    12241 tactgcactt ttaacacagg attatgatgt caaggaggct ataactggaa aagaaggtat
    12301 atctattgct gtctcatatt ctccagatgt tgttctttta gatttaggct tagaagatat
    12361 ggatggaata gaggtaataa aagctatcag acaattttca aatataccaa taattgtagt
    12421 ttcagctaga gagcaagata gagacaaggt agaagtattt gatgcagggg cagatgatta
    12481 cttaacaaaa ccattctcca tagtagagtt attagcaaga gtaagagtag catttagaca
    12541 ttcacaagta gaagctcaac aaaaagatga tgttaaatct acgtttgaag tagataaatt
    12601 attgattgat tttgataaaa gaaaagttat tgttgatgat gttgaagtcc atttgacacc
    12661 tattgaatat aatattcttt cattacttgc aaagcatcat ggaaaagtgc ttactcataa
    12721 ttttataata aaagaaatat ggggtagtgt tatagggaat gagactaagt ctctaagggt
    12781 ctttatggca acgttaagac gaaaaataga aaaacaacct gcaaacccaa gatatataat
    12841 tacagaagtt ggtgtaggat acagattaaa tgatgaatag ttgtaatata ttaattatta
    12901 gattatgcgc ttattaatat atattaaaat tatatagttt agttaaaata agaatgaagt
    12961 gtatgtgctt gttgtcagtt tagcacatgc attttatttt ttagcttttt tagtatcaat
    13021 aattttttag tatcaataat atgaaatatg ttttaaaata ag
//
LOCUS       DAEQAF010000102        13009 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.105, whole genome shotgun sequence.
ACCESSION   DAEQAF010000102 DAEQAF010000000
VERSION     DAEQAF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13009
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.105"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..681
                     /locus_tag="KRN00_003052"
     CDS             <1..681
                     /locus_tag="KRN00_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1828904.1"
                     /translation="RILNATISKEPSGRYYVSLCCTDVDIEAFENTNNHIGLDLGIKE
                     FCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLEVAGLQEHIANQR
                     KDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWHG
                     RQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGL
                     RLITTQNK"
     gene            1236..2642
                     /locus_tag="KRN00_003053"
     CDS             1236..2642
                     /locus_tag="KRN00_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBH1828905.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLDFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEILDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            2670..3518
                     /locus_tag="KRN00_003054"
     CDS             2670..3518
                     /locus_tag="KRN00_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1828906.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLPEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            4179..4871
                     /locus_tag="KRN00_003055"
     CDS             4179..4871
                     /locus_tag="KRN00_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828907.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            4868..5803
                     /locus_tag="KRN00_003056"
     CDS             4868..5803
                     /locus_tag="KRN00_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828908.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKFGHIYKRLKDIEEIL
                     ADVEIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYLDAVHSGIVIEQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            5951..6874
                     /locus_tag="KRN00_003057"
     CDS             5951..6874
                     /locus_tag="KRN00_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828909.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            6858..7628
                     /locus_tag="KRN00_003058"
     CDS             6858..7628
                     /locus_tag="KRN00_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828910.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPLLSVLPAPVIMRWWMAFWGDPTGEY
                     TVLRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            7638..8420
                     /locus_tag="KRN00_003059"
     CDS             7638..8420
                     /locus_tag="KRN00_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828911.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVILVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            8797..9333
                     /locus_tag="KRN00_003060"
     CDS             8797..9333
                     /locus_tag="KRN00_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBH1828912.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            9365..9754
                     /locus_tag="KRN00_003061"
     CDS             9365..9754
                     /locus_tag="KRN00_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBH1828913.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            9791..10177
                     /locus_tag="KRN00_003062"
     CDS             9791..10177
                     /locus_tag="KRN00_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBH1828914.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            10304..11746
                     /locus_tag="KRN00_003063"
     CDS             10304..11746
                     /locus_tag="KRN00_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBH1828915.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            12043..12858
                     /locus_tag="KRN00_003064"
     CDS             12043..12858
                     /locus_tag="KRN00_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1828916.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
BASE COUNT         4737 a         1584 c         2459 g         4229 t
ORIGIN      
        1 agaatactta atgctactat atctaaagag ccaagtggta gatattatgt atcattatgc
       61 tgtactgatg tagatattga agcatttgaa aatactaata atcatatagg tttagattta
      121 ggaattaaag aattttgtat ctcaagttgt ggagaattta tagaaaatcc taagtatctt
      181 aagaagtcat taaacaagct tgctaaatta caaagagaat tatcgagaaa aacaatcggt
      241 agtttaaata gaaataaagc aagattagaa gttgcaggac ttcaagaaca tatagctaat
      301 caaagaaagg attttttaca aaaactatct actaaattaa taaaagagaa tgatattatt
      361 tgcatagaag atttacaagt aaagaatatg attagaaatc gtaaactatc tcgcttaatt
      421 tctgatgtgt catggtcaga gtttattcgt caattagaat acaaggctaa ttggcatggt
      481 agacaaattg taaaggtggg taaattcttt gcaagttcac aaatatgcaa taaatgtggg
      541 tataaaaacg aggaagttaa ggatttaaat ataagagaat ggatttgtcc tagttgtaat
      601 gaaactcacg atagagatat aaatgcaagt ataaatatat taaaagaagg attaagacta
      661 ataacaactc aaaataaata acttatgtaa gaaccgtagg aactacgggg atagcctgtg
      721 gagaattagt aagacatatt ttagtatgca aaattctgtg aagcaggaac cctgtgactt
      781 tagtcatggg aggttcagtt tgggcaagta gtttcttgta aatctagtta tgtttcaacc
      841 aatgataata taatttcatt agtattagct ggtaattaag ttaatttgac tagagataag
      901 taaattgatt taaaaggaaa taagtaaatc aacaattaaa tacatctaaa agtaagttta
      961 ttgcaatgaa ttgttaaaga aaataattaa tatggagtaa atctattgca atgaagtaac
     1021 aaagaaaata attaatatag agtaagttta ttgtaatgaa ttgttaaaga aaagagttaa
     1081 tatagagtaa gtttattgta atgaattgtt aaagaaaata attaatatag ggtaaatcta
     1141 tctcaatgaa ataacaaaga aaagagttaa tatagagtga acttattgca atgaatcaac
     1201 aaagaaaata attaatataa aaaggagaaa tatttatgaa tacaggattt ccaaaagact
     1261 ttttatgggg agcatcatct tctgcatttc aagtggaagg agcttgggat aaagacaata
     1321 aaggaaaaac cgtagccgac tataattctt ttaaaaagtc tcatttacag gcagatacta
     1381 aagtcgcatc agacttttac cataattatg aagaagatat tgaattaatg aaagaattag
     1441 ggatgaaaac atatcgtttt tcaatttcat gggcaagaat aataccagat ggtgaaggag
     1501 agataaacca gaaaggttta gacttttata ataagataat agacaaacta atagagtgtg
     1561 atattgagcc attcgtaact ttataccatt ttgaccttcc atttaaatta gtagagaaat
     1621 ataatggttg ggaaagtaga gaaactgtct atgcttttga aagatttgct aaaatatgct
     1681 ttaagcattt tggagatagg gtaaagtatt ggcaacctca taatgaacag aatttaattg
     1741 ttagagtgga ggagagaatt aatatatatg atgaaacaga ttcatggaag atagataaaa
     1801 tgcgtgctca gatggattat aatctttgct tagcacatgc attagcagtc aatgcatgtc
     1861 atgagatgat aaaagaaagt aaaattggag cagcagtatc atcatctgta acatatcctc
     1921 ttacttctaa gccagaagat gtatatgcag ctagaatgaa tgataatttt aaagtgtact
     1981 atatgcttga tatgcatcat tatggagaat atccagggta ttatatgaag tatcttgaaa
     2041 aaagaaatat agttcctcac atggaagatg gggataaaga gatacttaaa aaagctaaaa
     2101 tggattttat agctgtaaat tattatagga caaattgtgc agaagcttta cctgaagatt
     2161 cacaacatcc atttggatta agagaaggaa ctgttgattt tagtatgtat ggactattta
     2221 aaatgtcaat gaatcctaac ttagaggctt ctgagtatgg agcagcaata gacccatcag
     2281 gtcttagagt tgccttaaat gaatattggc aaagatatca cttacctgtt ataataacag
     2341 aaaatggtct aggagctaaa gatatattag aagatggaaa aattcatgat gactatcgta
     2401 tagactattt aagaagtcat ataaatgcat gtaaactagc tattgaagat ggtgtagaga
     2461 tgattggata ttgtccatgg tcatttacag accttttaag ttcttctcaa ggttttaata
     2521 agcgttatgg acttgtttat ataaatagaa ctgaccatga aattttagat ttaaaaagaa
     2581 tcaagaaaga tagtttttac tggtataaag aagttataga gaacaatgga atagtaaaat
     2641 aaacataaat atatattgag ggttttagta tgtacattac aaaggtatta aataattcgt
     2701 tgctacttgc aaaggatgat aatgatgaag aaataatatt gatggggaaa ggcattggcc
     2761 ataattataa ggccgggtct gagttaaata aaaaagatat agaaaagatt tttgttcttc
     2821 atgatgaaaa tataaaaaag agtattatac aattggcaac agaaatagat gcagaatatt
     2881 ttggtatagc tcaaatgata attgcatatg gaatagaaaa atataactta aaacttatga
     2941 accatatata tttggcctta actgaccaca ttgcctttgc agtgagacgt tttaaagaag
     3001 gtataatgat tgaaaatcac tatttgttcg aaatcaagga atttaatcca aaagagtatg
     3061 atataggaaa atatgctatt actgttttta aggaggttct tggtttagac ctaccagaag
     3121 aagagattgg taatatagca ggccatttta taaatgcaca acaagataat ccttatagtg
     3181 atagaaataa gagaagtgct aaaattgtaa atgctatttt gcaaatagtt cattatcact
     3241 tttctattgt atataataaa gagtcatttt attataggag atttgtaatg catctaaagg
     3301 ccttttcaca aagatttctg gctaatgaac catcaagaga aaaaatagat tttatatatg
     3361 agcaagttca aaaaaattgt aaggaagagt atgaatgtgt gaaaaaggta ggagcttata
     3421 tgtataagga atactccaga gaattaccaa gacaagagga gttatatttg atgattcata
     3481 ttcataagat tttaggagaa ttatgcgaaa atagttagaa tatcttaata tgctagtaat
     3541 attataaaaa attaaaaatt aactacactt taaatatgaa taattgcatt acttaagggg
     3601 gttgtcttaa aattgatttt tttaattaaa tttgaagctc aactcctttt ttaaaccttt
     3661 atatcattac aactttaatg tttatacgcc tgtactttag atgtatatct actttttaca
     3721 tttctcaaca tgcaaaccca ccattttttg cagtatgtta attgaaataa accattgagt
     3781 taaccctaaa tttattctgg acttatagga atagttccaa agatacttta aaatattttc
     3841 tggaataatt gcttatttca catatgtttt attgtgatgt tttgatttaa taaattcttc
     3901 aactctgtat atagtaaatg tattatcatg tttgttttat tcaagcacac ttataatacg
     3961 cttgattttt tcacaatgat gaaatatact aatgggtgtt ataggtataa gaatagcatt
     4021 acacttgaag aagtaagtga taaatgagat ataaatcctc atatgataaa ctactatttc
     4081 attgaggagc atattctaaa tgatgtaaag atactacaat atgactaaat tcctagtgat
     4141 aaaaaagtct acgaatgagt gtagaaaggg gaactaagat gaataaagtt ttaattatag
     4201 atgatgataa agatctttgt attttgttaa aaaagagtat ttcaattgaa cagattgaag
     4261 caaactattg ccattctggg agagatggac tggttgaact ttcaaaacaa gattatcagt
     4321 tagtagttct agacgtgatg atgccaggta tggatggttt tgaaactatg gaacaaatac
     4381 gaaaatatag cagtattccc atcttaatgc tgacatcaaa aagcgataat tacagcaaag
     4441 tgcatggatt gcgagctggt gcagatgact atctaaccaa accatttgaa attacagaat
     4501 ttactgctcg tgtactgtct ttaatccgac gttacacccg ttttaatcca aaaaatgagg
     4561 agccacagca actttctttc aaaggtttgt tgattgacct tgaccagcat acagttacta
     4621 ccaatggcga acctatgttg cttccaccca aggaatttgg tgtacttctt tactgtgcaa
     4681 ggcatcaggg taagattttg acaaaacagc agatttatga agccgtgtgg ggtgagccat
     4741 atgtatatga tgacagcaat atcatggcta ttatcagtcg cctaagaaaa aaaattgaac
     4801 tagacccatc atctcccatc tatttgcaaa caataaaagg aattgggtat caattcaaca
     4861 cggaggtatg aaaatggatg aacaaacgat aattcttttc ttactcttgc tgtcgattgg
     4921 tctacttttt ctttccatat ttgctttttc caagtttggg catatttaca agcgcctaaa
     4981 agatatagag gagatactgg ctgatgtaga aattggagac gaaaatcgta aaatactaat
     5041 taagccatgt gatgttatgg ctccattggt ttatcagctt aatgagattg tctacgatta
     5101 tgaaaataag ttactttctc tgaaaaagtc ggataaagct agcaaacaac ttatgacaag
     5161 tttatctcat gatgttcgta caccattaac aactctgatt ggttatctgg atgctgtaca
     5221 cagtggtata gttatcgaac aagagcggga ggaatacctt gaaatcgcta ggcgtagagc
     5281 ctacgacctc aaggattaca ttgatgttct ttttgactgg tttcggttga actctgatga
     5341 atttacgctg tcaatagaat ctgtggaaat tgcagagttg tcacgcaata ttttgaaaga
     5401 ctggattcct atattccatg aaaagaaact gaattttgaa attgatattc cagaaaatcg
     5461 actaatggta aacctcgacc cagatggata ttcccgtgtg gtcaataatc tggttcaaaa
     5521 tgttcttgct cacagtaagg ctcggcaaat caagattacc atgagtgagg attccagaat
     5581 ggtattactc cgtgttgagg atgatggtgt tgggattgcc agagaaaatt taccacatat
     5641 ttttgagcga ctgtataagt gtgataaagg acgttcagaa aaaggaagtg gtcttggtct
     5701 atctattgtc agtcaaatgg tggagcgaat gggtggtcag gtttccgtag aaagtgagat
     5761 tggaaagtat accgtattta cagtgagctt accattaata taaaattgtt tttcccccat
     5821 gtgacatgta tacacagggg gattttttgt aagttataaa gttgcaaggt taatacaagg
     5881 ttgttgcaag gttaatgtaa gattgaggtg gtatgataac tttaataaac aaaggaggct
     5941 tttattattt atgaataatt taattattga aacaaaaaat ctcactaagc aatatggtgc
     6001 tcaaaagagc gtttctaatt tgaatattca cgttcagaaa ggtcgcattt acggattgct
     6061 aggaagaaat ggtgcgggta agacgacaac tatgaaaatg ttattgggtc taacaaaacc
     6121 aactactgga gaaattaaaa tatttggtca ggacattcac aataacgaga agaagcttct
     6181 tcctcgaatt ggatgtttga ttgaatcacc agggttttat cctaatctga caggaacaga
     6241 aaatcttaaa atctttgcaa ggcttagagg aataccaaaa aaaaatgcag tagaatcagc
     6301 actggatgta gtcggtttgc caaacaatga caaaaagtta ttttctcaat actctcttgg
     6361 tatgaaacag aggttggcga ttgctcttgc cattatgcat gacccacaac tgttgatttt
     6421 ggacgagcct atcaatggac ttgatcctat tggtattgca gaagtaagaa cgtttattcg
     6481 tgatctctgc acagaacgag gtaaaactat tttgatttcc agtcacattc tttctgaaat
     6541 tgccttgttg gcagatgaca ttggcattat tgaccatggt attttgttgg aggaagaaag
     6601 tcttgcccaa ttagaagaaa aaaacagtaa atacatacat tttgctgtat ctgatgcagc
     6661 acaggcagca aggcttctgg aaacccaact taacctgaaa aatttcaaag tagcagataa
     6721 ttacaatatt atgctatatg atacagatgt ttctgttgca gaaataaatc gtgctttcat
     6781 tctaaacaac attgaggtat cagaatctca tttatgcgaa gatactcttg aagattactt
     6841 caagaaagta acagggggtg aaggaattgc ttgatataat ttcatgtgaa ttttcaaaac
     6901 tcaagcggtt aaaatttata ctgatttcta ttttaggtgc ttgcttattt ccaattcccg
     6961 caacaatttt gattgcaaag gacaacttgc cctttgagca attgttcaaa ttagttgtca
     7021 attttggata ttttttgcta ttaccaattg tattaagtat tgttgctagc caactatttt
     7081 ttatagaaag agataatgat gtattaaaaa atcttgcaac agtgccagtg caaaaaggaa
     7141 aactggctct ggcaaaattg gctgtgttgc tgtttatatc attgttctac tccgttgcag
     7201 ggttaggagc tactatcatt ggaggtttca ttgttggaat agtagagggg gttgctgtaa
     7261 aattaggaat gagcattgct tttggaatta tgttttttgt tactgtactt cctgttgtgg
     7321 tactcattgt atatttcaat cgcagctata ttttttctat tatactttct tttgtatatg
     7381 ctattttcaa ttttagtata tccttaaata ttatcaattt tgaaccaaat aacccactat
     7441 taagcgtatt acctgctcct gttataatgc gttggtggat ggcattttgg ggagatccca
     7501 ctggcgaata cacggtactt agacagccat atttgctctc aactcctgct tgtgtaggta
     7561 ttttatgttt gataaccatt atagcagtcc tgctgatttg tatgatatac aaaaagcagg
     7621 agaattagga ggtatctatg cttgatataa ttactacaga atttcaaaaa ataaaaagat
     7681 ataatattct atggattggt gttgttgctg ttctgttttc agcactattg gcagtttttc
     7741 aggttgtaag ttcacatggc agtgaccctc taacgtatga gagctttgca aacggagtta
     7801 tctggaataa tttcagtctt agttttccat ttgggattac acttattgga ggatatctta
     7861 ttaaccgtga atatacagac caaaccttaa aaaacatcct aactgttcct atttcattac
     7921 gcaaattgct agtgggaaaa ttaattgcgg ttggaggaat tactgtattg ttaagtcttt
     7981 tcagcttctt atgcacattt attttggggt tgttattttg caatatcaat atatctgtta
     8041 tactcgttgt aaaatcctta gttcagattt tgtctgttaa tctgtactgt tatgttgctg
     8101 ttttgccgat tattgcttat tttggtcgta aacaaaatgc atttctgacg ggtgtaggga
     8161 ttgcatttgt atacggtttt tgtggtgtgt ttgttgctgg aagaaatctg acagactttt
     8221 atccaatcac agcaggtctt ggtctagttg gatacaacaa tggtgctggt actgtttatc
     8281 agccacttat cggtgctatg actttgattg taattctaat cttgacaact attctacttg
     8341 tatttacacc taattatgat aaagttatga ccatatctaa gaaaaaaggg ataaagcata
     8401 aaaagtattc tcataaataa cataaatatt gtttctatta tttaagttgc tagacagtga
     8461 aaagaaaaaa tctgtcgtac agtggctata tgctcatgta ttcaagaagc tacagttttg
     8521 atttttcata actgtagctt ctttttgtat ttattaaatc acgactatca taatacttgc
     8581 aataggtata gcgacaagag agagtactgt catatgtgtt ttatatatta cattaagtat
     8641 attctaaaat atatgtttta aataatatat ttgaaaatag gaatatttaa ataaaaaaaa
     8701 taatattata tatagttgac aaaaattggc aaatgagata ctatataaat atagaaatag
     8761 taatcattac tattattaaa aagggaggaa ttaattatga acttaaaagg aactaaaaca
     8821 gaaaagaatt taatggcagg atttgcagga gagtcagaag caagaaataa atatacatac
     8881 tacgcttcaa aagcaagaaa agaaggttat aatcaaatag ctgctatatt tgaagaaact
     8941 gctaacaatg aaaaggaaca tgctaaatta tggtttaaac ttttacatga tggtatgcct
     9001 tcaacagagg aaaatttaaa ggatgcagca gcaggtgaaa actatgaatg gactgatatg
     9061 tatgcaaaat ttgctaaaga agctagagaa gaaggatttg acaagatagc ttatttattt
     9121 gaagctgttg gaaaaataga gaaagagcat gaagaaagat acttaaagct tttagaaaac
     9181 ttaaatgaag gaaaaatatt taaaagagat gaagaagttg tttggcaatg tcaaaactgt
     9241 ggtcatgtgt atgtaggtac tgaagcacca gaaaaatgcc cagtatgtga ccatccaaaa
     9301 gcatatttca atataaaagc tgaaaattat taaaaattat cattattaaa aaggaatgtt
     9361 aactatgaaa ttttctaaac aacgagaact gattttaaat gaaatattaa ataatccggt
     9421 tcatcctact gcggattacc tatatgaaaa cttaaaaaaa gataatccaa atttaagctt
     9481 aggaactgtg tatagaaatt tagctcagct aacggaacat ggctttataa gaaaggttag
     9541 tattccaggg tatccagata gatttgatgg tcgaatagat aatcactatc atatcatatg
     9601 tgaagtatgt ggagaggtat acgatttaga atccgaagtt cttaataatt tacaagaatt
     9661 aatatctgag gagacagaca taaaaataac atcttataac ataagtttta aagggatttg
     9721 taataattgt aaaaggtgta gccaagtagg ttagttttca aattctaaaa ataattaatg
     9781 aggtgagttt atgtgtagtg aacaaaaatt ttttatatgt gagacttgtg gaaaccttgt
     9841 aggaatgata caaagtggtg gtgtacctat tttctgttgt ggaaaaccta tgaaggaact
     9901 tgttcctaat acaacagatg cagcagttga aaaacatgta cctgtaattg aagtggatgg
     9961 aaataatgtt actgttaaag taagtagcac aactcatcca atgactaaag aacatcatat
    10021 agcatgggtg tatcttatga ctgaacaagg tggtcaacgc aaatgtctag cagtagatgg
    10081 agaacctgta gttaaatttg ctttgaatga tgatgataaa gtgatttctg cctatgctta
    10141 ctgtaattta catggattat ggaaggctga actgtaatat ttaaataaat tgagtcaaaa
    10201 aggaggctat aaatgtattt tcatacaaat agcctcctat aaatttatat aaattcaagt
    10261 tttaattttg tttaatgtca atataatata aggagaaaat aatatgtcaa tttataaatg
    10321 tagtgtttgt ggatatattt atgatgaatc taagaatgat aaaacatggg atgaattaag
    10381 tgaagattgg gaatgccctg tatgtacaaa aggtcgtagc tattttggaa agataagtac
    10441 tgtttactat gaagaagatg aaaagatagc agaagacata gttgaagatg aatctaaatt
    10501 aaatactgaa aaagagggag atttaaatta cttaagtaca tatttaagaa gagatgatga
    10561 agttgagaaa catatggata taattcacga aatggctgtt acaggaaaat ctataataga
    10621 acctatgaga acgaaactac cagtaatttc ttgggatgat attttaatta tgggtgctca
    10681 attaaatcca ttacctttaa atgagcatga tgaagtaaat acaacaacaa taataggaaa
    10741 aaaagcaaag aaacctatga ttatagaaaa tccagtttat atttcccaca tgtcatttgg
    10801 agctttgtct aaagaactaa aaatagcttt agcaaagggt gcagcccaaa ataagacagc
    10861 tatgtgtagt ggtgaaggag gtatattacc agaagagaag gaagcttcat acaagtatat
    10921 ttttgagtat gtaccaaata aatatagtgt aactgaagaa aatcttaaaa attctgatgc
    10981 tatagagata aaaattggtc aaggaacaaa acctggtatg ggaggtcatc ttcctggcga
    11041 aaaagtaact gaagaaatag caaaagtaag aaataagcct gtaggtcaag atgtaataag
    11101 tccatcttgt tttgaggaaa tacaatccaa agaggattta aagaaacttg tagatgaact
    11161 tagagaagtt tcagaagggc gtccaatagg tgttaaaatt tcagcaggtc atattgaaaa
    11221 agatatggaa tttatagctt atgctaaacc tgattttgta actattgatg gtcgtggtgg
    11281 agctactgga gcaagtccaa agttgcttaa agatgcaact tcaattccaa caatatttgc
    11341 tctttatcgt gctagaaaat acatagatac acatggatta gatatagatt tggttataac
    11401 aggtgggctt cgtatatcta ctgattttgc taaggcaatt gctatggggg ctgatgcagt
    11461 tgctattgca agttctgctc ttatggcagc ggcgtgtcaa caatatcgta tatgtggttc
    11521 tggtaagtgt cctgtaggag tagctactca ggatgaggaa ttgagaaaaa gattacatat
    11581 agaaaatagt gctaatagag tggcaaactt tttaaatgta agtttagaag aacttaagac
    11641 ttttgctaga atttctggtc ataaagatat acatgattta agtgttgatg atttatatac
    11701 tgttaactct gaaatatcaa attatacaaa catacagcat gtatagattg aagtttgaaa
    11761 ctattagatt ttagatagct ataaaagtaa atgataaata tattttataa aatagagtgt
    11821 cttaaaatga actttttagt tcataagtca ctcttttttg tatgaagcca aatatattta
    11881 ttattttagc aatgaaaaag aatcttatct ctttattttg agatagactc cttctattta
    11941 tgaaaattaa agatattaaa ttgtaaaata ttctgtgatg tcgtactatt aaactaaaga
    12001 ttctatactt taaagtaaat aaaaatttaa ggagtgatta ttatggaaag attgaagata
    12061 caagttttag tcgacaataa tacttatatt gatagatact ttgttggaga accagcagta
    12121 agctattata ttgagattga tggaaatagg attttgtttg actcagggta ttcagatgta
    12181 ttcatatcaa acgctgaaaa attaaatata gatttaggaa atttaactca tgttgttttt
    12241 tctcatgggc ataatgacca tacaagaggt atccagtttt tagaaaatag gtatgattta
    12301 tctacagttg aacttatttc acatcctaac tgttttatac ctagaaaaca tggagagaaa
    12361 agcataggag ctccattttc tgctgaggaa attaaaaata tttttatgta taatcctaag
    12421 gataagccat ttaatctaag caagaattgt gtgtttttag gtgaaatacc ttctataaat
    12481 gattttgaaa aaagagctaa aattggtaaa tgtaaaatag gagatttgtg ggaagatgat
    12541 tatgttttag atgattctgc tatagtttgt aaaactgata aaggtatttt tattgttaca
    12601 ggatgttctc atagtggaat ttgtaatata gtagagtatg ctaaaaaggt atgtggagat
    12661 gatagagtta ttggtatact aggtggtttt catctttttg aattgaataa taggttagat
    12721 agtacaatac aatatttgga taaagaagaa atgagaatgt tgtacccttg tcactgtgtt
    12781 tcttttaagg taaaagcgaa gatgaatgaa atattgaata taaatgaagt tggagtaggg
    12841 ctgaccataa gtatatagta tttgaaagta tataagattt aagttgaagg ttaaaaagat
    12901 attttctata taaaatatct tttttgttac gtttatttta agagaaatca atatactttt
    12961 atatgaaata ttgtaaaaaa atttattttt aatgagaata tattttcat
//
LOCUS       DAEQAF010000103        12654 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.106, whole genome shotgun sequence.
ACCESSION   DAEQAF010000103 DAEQAF010000000
VERSION     DAEQAF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12654
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.106"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            179..2524
                     /gene="secA"
                     /locus_tag="KRN00_003065"
     CDS             179..2524
                     /gene="secA"
                     /locus_tag="KRN00_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBH1828917.1"
                     /translation="MSVLDAILDKADEQEIKKLNLIVDKIESLEKDMEIKENEQLKEM
                     TNTFRLRLDKGESLDDILPEAFAVVREVSKRVLGMRQYKVQLIGGIVIHQGKIAEMKT
                     GEGKTLVEVAPVYLNALTGKGVHVITVNDYLAERDKELMRPVYEFLGLTVGVILSNQD
                     PSIRKEQYKCDITYGTNSEFGFDYLRDNMVPDLSHKVQRELNFAIVDEIDSILIDEAR
                     TPLIIAGDGDEDLKLYELANNFVKTVKEEDFEMDRKDKTIALTASGISKAESFFGITN
                     LTDIKNIELYHHINQALRGHKLMEKDVDYVISNGEVMIVDEFTGRVMDGRRYTDGLHQ
                     AIEAKEGVEIKNESKTMATVTYQNFFRLYEKLSGMTGTAKTEEGEFESIYKLNVVQIP
                     TNRPVIRADLHDKVFKTEEEKYSAVVEEIIRIHKTRQPILVGTVSVEKSEKLSKMLKK
                     QGIKHQVLNAKQHDKEAEVISKAGKLDAITIATNMAGRGTDISLGAGDKEEEEKVKNL
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDDVIKLYGGKTIEKLMKR
                     TSSKENTAIESKALTRAIERAQKGVEGKNFEIRKNVLKYDDTINEQRKVIYNERNKVL
                     NDEDIKEDIQKMVKDIIQEAGETYLIGRKRDYYGYFKHLYSTFMPADTLLIPGVDKKS
                     VQEIIDSTYEISKRVYDLKKMMIGIDKVAELEKTVLLKVVDQYWIDHIDAMEQLRQYI
                     GLKSYAQKDPFKEYALEGYDMFEALNKNIREATVQYLYKFN"
     gene            2939..4810
                     /locus_tag="KRN00_003066"
     CDS             2939..4810
                     /locus_tag="KRN00_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp2"
                     /protein_id="HBH1828918.1"
                     /translation="MNKKNLSVIMAAAMISTSVAPVFAAETTQVKKETITKKEATELV
                     SKVRGLMSQKYTGGSQVGQPIYEIKVGETLSKLKIITNIDELEKLVNALGENKELIVT
                     ITDKGHITNSANEVVAEATEKYENSADLSAEANSITEKAKTETNGIYKVADVKASYDS
                     AKDKLVITLRDKTETVTSKTIYVGIGDEKVDLTANPVDSTGTNLDPSAEGFRVNKIDK
                     LGVAGAKNIDDVQLAEITIKNSDLNTVSPQDLYDGYRLTVKGNMVANGTSKSISDISA
                     KDSETGKYKFTIKYTDASGKATELTVESTNEKDLKDAKAALEGNSKVKLIAGDDRYAT
                     AVAIAKQTKYTDNIVIVNSNKLVDGLAATPLAQSKKAPILLASDNEIPKVTLDYIKDI
                     IKKSPSAKIYIVGGESAVSNTAKKQLESVTKNVERLAGDDRHMTSVAVAKAMGSFKDA
                     FVVGAKGEADAMSIAAKAAELKAPIIVNGWNDLSADAIKLMDGKEIGIVGGSNNVSSQ
                     IENQLADVDKDRKVQRVEGETRHDTNAKVIETYYGKLDKLYIAKDGYGNNGMLVDALA
                     AGPLAAGKGPILLAKTDITDSQKNALSKKLNLGAEVTQIGNGVELTVIQKIAKILGW"
     gene            4917..5624
                     /locus_tag="KRN00_003067"
     CDS             4917..5624
                     /locus_tag="KRN00_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1828919.1"
                     /translation="MVDATLFFTPHQDDETLSMGSAIIEHVEKSDTHVILCTDGSKSI
                     IRKVLDDGGSCSYHIKDVHKYSLSENEFSKDRDEEFKDSCEAMGVKESNIHIEDNRAH
                     DGELSKEKAREIILKYLEEYPDAKVKTVTPFKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYKDFKKVNPNVEVWKVLPSQEEKLLSAMNAYKKWNPESGHYAIGYHSVK
                     SHFDELATNKIQYVHAP"
     gene            5657..7492
                     /locus_tag="KRN00_003068"
     CDS             5657..7492
                     /locus_tag="KRN00_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1828920.1"
                     /translation="MKISKKIVSLLTITFLTIMLYGNTSNASTKDTLTGSGRWETAIK
                     ISQAGWTKSESAVLVNDNSIADALSATPFAKAKDVPILLTQSNKLDSRTKAELKRLGV
                     KNVYLIGGSIALSSEIEKQLNAENISFERISGNSRYDTSLKLAEKLDREKSISKIVVV
                     NGEKGLADAVSVGAIAAQENMPIILSDSENGTEVADNFIDSKDIEKSYVIGGTYSISN
                     SVERSLPNATRIAGSSRSETNAKIIEEFYKDTDIKNIYVTKDGTRSKHDLIDSLAVGV
                     LASKNGSPILLAGNKLDSSQKDVLNTKIIDKVIQIGGLGNENVVEDVIDMQEETKYTV
                     ETIDELNVAIKKSDANDIIRFKPEKDKNITNSFKIETNKAITIEFDGIYKQSITIDMP
                     NGDIKNFGDIDNDLVINNIKNETLVNEGSIQGIDVYDENGCKIENEDSGEIWLITILK
                     NSKDVYILNRGEITKISNNSSSVTIKNSGNINTISGSEEPSISGKKPITNDTDKDEDK
                     KARGLYPKVESCIPALKDYVRITISTKPESSKYKIYYRVVDEKPSAKYVGEKISTKGW
                     SMVTISNQSFIERAKDGSYIEAVEIDTSNNEVSRWGKSSITDDGI"
     gene            complement(7540..7935)
                     /locus_tag="KRN00_003069"
     CDS             complement(7540..7935)
                     /locus_tag="KRN00_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBH1828921.1"
                     /translation="MILKKYKETILYLFFGAFTTLVNIVSYLFFTRVILFNFMVANAL
                     AWILAVLFAYVTNKFFVFESKRIEIKFLFKEFLSFVSFRLLSGVVEMLIMYVMIDLLF
                     VNDVIVKIFTNIVVIVLNYLFSKMIIFKK"
     gene            8162..10573
                     /locus_tag="KRN00_003070"
     CDS             8162..10573
                     /locus_tag="KRN00_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBH1828922.1"
                     /translation="MRKYKSKKLSKLLALLTVCFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMDLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEEDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETD
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGESLT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGSDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNENAFNELN
                     TLLGK"
     gene            10870..12447
                     /locus_tag="KRN00_003071"
     CDS             10870..12447
                     /locus_tag="KRN00_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBH1828923.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIKSLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKENTVNEAFRMVTNKPITVNIKGDCSKTLTVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGTIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
BASE COUNT         5281 a         1408 c         2286 g         3679 t
ORIGIN      
        1 ttcgaataca aaaaaagaga ctaaatttag tctctttttt atgtgagaaa tacttaaata
       61 tataaagatg taatttattt aagtatgatt attatactat acaataaaat aattgtctac
      121 tattctataa ttttaaggta taataataat tgtatgataa aaaaggaggt caaaaaatat
      181 gtcagtttta gatgcaatct tagataaagc ggatgaacaa gaaattaaaa aattaaattt
      241 aatagtagat aaaatagaat ctttagaaaa agatatggaa atcaaagaga atgaacaatt
      301 aaaagaaatg acaaatactt ttagacttag attagacaaa ggtgaaagtt tggatgatat
      361 acttccagaa gcatttgctg ttgttagaga ggtctcaaaa agagttttag gaatgcgtca
      421 atataaagtt cagttaattg gaggtatagt aattcatcaa ggaaagatag ctgagatgaa
      481 gactggtgag gggaaaactt tagttgaggt agctccagta tatctaaatg ctttaacagg
      541 aaaaggtgta catgtaatta cagtaaatga ttatttggca gaacgtgata aagaacttat
      601 gcgtccagta tatgaatttt taggattgac tgtaggtgta attttatcta accaagaccc
      661 aagtataaga aaagaacaat ataaatgtga tataacttat ggaacaaata gtgaatttgg
      721 atttgactat ttaagagata atatggtgcc agatttgtct cataaagtac aaagggaact
      781 aaactttgcc atagtagatg agatagactc aatattaata gatgaagcta gaactccact
      841 tattattgca ggagatggtg atgaagattt aaaactttat gagttagcaa ataactttgt
      901 aaaaactgtt aaagaagaag actttgagat ggatagaaaa gataaaacta tagcattaac
      961 agcaagtggt ataagcaaag ctgagtcatt ttttggtata acaaacctta ctgatataaa
     1021 gaatatagaa ttatatcatc atataaatca agctttaaga ggtcataagc ttatggaaaa
     1081 agatgttgac tatgttatct caaatggaga agtaatgata gttgacgaat ttacaggaag
     1141 agtaatggat ggtagaagat atacagatgg acttcaccaa gctatagaag ccaaagaagg
     1201 tgttgagata aagaatgaat ctaaaactat ggctactgtg acttatcaaa atttcttcag
     1261 actatatgaa aaactttctg gtatgactgg tactgcaaag acagaagaag gggaatttga
     1321 gtcaatctat aaattaaatg ttgtccaaat accaactaat agaccagtta ttagagctga
     1381 tttgcatgat aaggtattta aaacagaaga agaaaagtat agtgctgttg tagaagaaat
     1441 aataaggata cataagacta gacagccaat actcgtggga acagtttctg ttgaaaaatc
     1501 tgagaagtta tctaaaatgc ttaagaagca aggtattaag catcaagtct taaatgctaa
     1561 acaacatgat aaagaggcag aggtaatttc taaagctggt aaattagatg ctataacgat
     1621 tgctacaaat atggcaggta gaggtacgga tatttctcta ggtgcaggag ataaagaaga
     1681 agaagaaaaa gttaaaaatt taggtggtct ttatgttata ggaacagaaa gacacgaatc
     1741 aagaagaatt gacaatcagc ttagagggcg ttctggtcgt caaggagacc caggtacatc
     1801 aagattcttt gtaagtcttg aagatgatgt aataaagctt tatggtggaa aaactataga
     1861 gaaacttatg aagagaacaa gttcaaagga aaatacggct attgaaagta aagcacttac
     1921 aagggctata gaaagagcac aaaaaggtgt agaaggtaaa aattttgaaa taagaaaaaa
     1981 tgttcttaaa tatgatgata ctattaatga gcaaagaaag gttatatata atgaaagaaa
     2041 taaagtgtta aatgatgaag atataaaaga agatattcaa aaaatggtta aagacatcat
     2101 acaagaagca ggagaaactt atttaattgg aagaaaaaga gattattatg gatattttaa
     2161 acatttatat agtacattta tgcctgcaga tacattacta atacccggtg tagataaaaa
     2221 aagtgtccaa gagataattg atagcacata tgaaatttca aaaagggttt atgacttgaa
     2281 aaagatgatg attggtattg ataaagttgc ggagttagaa aaaacagtac ttttaaaagt
     2341 ggttgatcaa tactggatag atcatataga tgctatggaa cagttaagac agtatatagg
     2401 tcttaaatct tatgctcaaa aagatccgtt taaagaatat gctttagaag gatatgatat
     2461 gtttgaagct ttaaataaaa atataaggga agcaacagta caatacttat ataaatttaa
     2521 ctaaaaaagt tcatgtaatt tttattaaat gaaaaataaa atattttgat tctttatatt
     2581 gtaattacaa ttaaataatt aaggaataca aatgaaaaag aagctgaaaa tcagcttctt
     2641 tttctgtgtg agaaatacgg aaaaaagaga tgcttgaaat ttctttcttc catttaatat
     2701 tatactataa agaagatgaa aagtctatta gttataaact ggattattaa aaaaaattac
     2761 aattttgtta cttttttgta tacataaata ttaaaaaaat aaaatataag aaaaagttta
     2821 tatcttttgg ttaattatta caataagtct catttattga aataatatca aatatatatt
     2881 ataattggta aataaggaaa aaataataaa aatttgaatt ttttaggggg aaaataccat
     2941 gaataaaaaa aatctttctg taattatggc tgctgcaatg ataagtacat cagtagctcc
     3001 agtttttgcc gcagaaacta cacaggtaaa aaaagaaaca ataactaaga aagaggctac
     3061 agaactagtt tcgaaagtta gaggtttaat gtctcaaaag tatacaggag gttctcaagt
     3121 tggacaacca atatatgaaa taaaagttgg tgagacttta tcaaaattaa aaataataac
     3181 taatatagat gaattagaaa aattagtaaa tgctttggga gaaaataaag aacttattgt
     3241 aactataaca gataaagggc atataacaaa tagtgcaaat gaagtagttg cagaagcaac
     3301 tgaaaaatat gaaaattcag cagacctttc cgctgaagct aattctataa cagaaaaagc
     3361 taaaactgaa accaatggaa tttataaagt tgcagatgta aaagcttcat atgatagtgc
     3421 taaagataag ttagttataa ctttaagaga taaaacagaa acagtaactt ctaaaactat
     3481 atatgtaggt attggtgatg aaaaagttga tttaacagca aatccagttg attcaactgg
     3541 aacaaattta gacccttctg cagaaggatt tagagtaaat aaaatcgata aactaggtgt
     3601 agcaggagct aaaaatattg atgatgtcca attggccgaa ataactataa aaaatagtga
     3661 cttaaataca gtttcaccac aagatttata tgatggatat agattgactg ttaaaggtaa
     3721 tatggtagca aatggtacat caaagtcaat tagtgatatt tcagcaaaag attcagaaac
     3781 aggaaaatat aaatttacta ttaagtatac tgatgcatct ggaaaagcaa cagagcttac
     3841 tgtagaaagt actaatgaaa aagatttaaa agatgccaaa gctgcattag aaggtaattc
     3901 aaaggttaaa ttgatagctg gagatgatag atatgcaact gcagtggcta tagcaaaaca
     3961 aacaaaatat actgacaata tagttatagt taattcaaat aaactagttg atggattagc
     4021 agctacacca cttgctcaat ctaaaaaagc acctatatta ttagcatccg ataatgaaat
     4081 accaaaagta actttagatt atataaaaga tataattaag aaaagcccat cagctaaaat
     4141 atatatagta ggtggagaat cagcagtatc aaatacagct aaaaagcaat tagaatcagt
     4201 aactaagaat gttgaaagac tagctggaga tgatagacat atgacttctg tagcagtagc
     4261 aaaagctatg gggtctttta aagatgcatt tgtagtaggt gcgaaagggg aggctgatgc
     4321 tatgagtata gctgccaaag ctgctgaact taaggctcct ataatagtaa atggctggaa
     4381 tgatctttca gcagacgcta tcaaattgat ggatggaaaa gagattggta tagttggtgg
     4441 ttctaacaat gtatctagtc aaattgaaaa tcaacttgct gatgttgata aagatagaaa
     4501 agttcaaaga gttgaaggag aaacaagaca cgatactaat gctaaggtta tagaaacata
     4561 ttatggaaaa ttagataaac tatatatagc aaaagatgga tatggaaata atggtatgct
     4621 agtagatgca ttggcagcag gacctctagc agcaggtaaa ggtccaatac ttttagctaa
     4681 aactgatata acagactcac aaaagaatgc acttagtaaa aaattaaatc ttggtgcaga
     4741 agtaactcaa ataggtaatg gagttgaatt gacagtaata caaaagatag ctaaaatact
     4801 aggttggtaa taacttatac tgtggagaag attccttaat taatacagga atctttttct
     4861 ataattatgc tatttattgt aaattataac attttataaa gtaggaggat gtagtagtgg
     4921 tagatgcaac tttatttttt acaccacatc aagatgatga aaccttaagt atgggaagtg
     4981 ctataattga acatgttgaa aaaagtgata cacatgtcat attatgtaca gatggtagta
     5041 aatctataat aagaaaagtt ttggatgatg gagggtcatg ttcttatcat attaaagatg
     5101 ttcataaata ctctttatca gaaaatgaat tttcaaaaga tagagatgaa gaatttaagg
     5161 atagctgtga agcaatgggt gtaaaagaaa gtaatataca tatagaagat aatagagcac
     5221 atgatggtga gttaagtaaa gaaaaggcaa gggaaataat acttaagtac ttagaagaat
     5281 atccagatgc aaaagtaaaa actgttactc cgtttaaagc tagtggaata catgaagacc
     5341 atagggcatt aggagaagct gcactagagt tatataaaga aggcaaaata aaagatttaa
     5401 gattttatgt agaaccatat gactataagg attttaaaaa agttaatcca aatgtagagg
     5461 tatggaaggt attacctagt caagaagaga aattattaag tgcaatgaat gcatataaaa
     5521 aatggaatcc tgaaagtgga cattatgcta taggatacca ttcagtaaaa tctcattttg
     5581 atgagctagc tacaaataaa atacagtatg tacatgctcc ataaaatatt atgaaagaat
     5641 taggaggtaa gaattaatga aaatatcaaa aaagatagtg tccttgttaa ctataacatt
     5701 tttaactatt atgttatatg gaaatacatc taatgcatct acaaaagata cattaacagg
     5761 ttctggaaga tgggaaacag caataaaaat aagtcaagct ggatggacaa agtctgaaag
     5821 tgctgtatta gtaaatgata attcaatagc agatgcttta tcagctactc catttgcaaa
     5881 ggcaaaagat gtaccaatat tattaactca aagtaataaa ttggatagta gaacaaaagc
     5941 agaattaaaa agacttggtg tgaaaaatgt atatttaata ggtggttcaa ttgcattaag
     6001 ttcagagatt gaaaagcagt taaatgcaga aaatataagt tttgaaagaa tatctggaaa
     6061 tagtagatat gatacttctt taaaattagc tgaaaagcta gatagggaaa aatctatatc
     6121 taaaatagta gtagtaaatg gagaaaaggg tcttgctgat gcagtgagtg ttggagctat
     6181 agctgctcaa gaaaacatgc caataatact ttctgattca gagaatggaa ctgaagtagc
     6241 tgataatttt atagatagta aagatataga aaaatcgtat gtaataggtg gtacatattc
     6301 tatttctaat tctgtagaaa gaagtttacc aaatgcaaca agaatagcag gtagtagtag
     6361 aagtgagaca aatgcaaaaa ttatagaaga attttacaaa gatactgata taaaaaatat
     6421 ttatgtaaca aaggatggta caaggagtaa gcatgattta atagattctt tagctgtggg
     6481 tgtattagct tctaaaaatg gttctccaat acttttagca ggaaataagc tagatagttc
     6541 tcaaaaagat gtgttaaaca ctaaaattat agataaagtt attcaaattg gcggattggg
     6601 taatgaaaat gttgtagaag atgtaataga tatgcaagaa gaaactaagt atactgttga
     6661 aactattgat gaacttaatg ttgctataaa aaaatcagat gcaaatgaca tcataagatt
     6721 taagccagaa aaagataaaa atataactaa ttcttttaaa atagaaacaa ataaagctat
     6781 aactattgaa tttgatggta tatataaaca atcaataact atagatatgc caaatggaga
     6841 tataaaaaac tttggggaca tagataatga tctagtaata aataatataa aaaatgagac
     6901 tttagttaac gaaggaagta tacaagggat agatgtttat gatgagaatg gatgtaaaat
     6961 agagaatgag gattctggag aaatatggct tataacgata cttaaaaatt caaaagatgt
     7021 atatattttg aatcgtggag aaataactaa aatatctaat aattcttcta gtgtaacaat
     7081 aaaaaattca ggtaatatta atactataag tggaagtgaa gaaccatcaa taagtggtaa
     7141 aaaacctata actaatgata cagataaaga tgaagataaa aaggcacgtg gtttatatcc
     7201 taaagtagaa tcttgtatac ctgctttaaa agattatgta agaataacta tatcaacaaa
     7261 accagagagt tcaaagtata aaatttatta tagagtagtt gatgaaaaac catctgcgaa
     7321 atatgttgga gaaaaaatta gtactaaagg ttggagtatg gttacaatat caaatcaatc
     7381 ttttattgaa agagccaaag atggatcata tatagaagca gtagaaatag atacctcaaa
     7441 taatgaagtt tcacgatggg gaaaatctag cattacagat gatggaattt agacattaaa
     7501 cttattcatt ttgcagatta ctatttagta atctgctatt tattttttaa aaattatcat
     7561 cttgctaaac aagtaattta aaactataac aactatatta gtaaatattt ttacaataac
     7621 atcatttaca aaaagcaaat caatcattac atacataatt aacatttcaa cgacaccaga
     7681 aagtagccta aaactaacaa aagacaaaaa ttccttaaat aagaacttta tttcaattct
     7741 tttactttca aacacaaaaa acttattagt aacataagca aataaaacag caagtatcca
     7801 tgccaaagca tttgcaacca taaaattaaa taaaataact ctagtaaaaa ataaatacga
     7861 aactatattt acaagagtag taaatgctcc aaaaaataaa tataatattg tctctttata
     7921 cttttttaaa atcaaatata atcctcctaa gctaatttaa tataaatata cttaaagata
     7981 ctaacaaaca ttagtatagc acatctatta ataaatcaat atatcttaaa atattataaa
     8041 aataaaacta taatattcta taattaatat gtactcataa tccatatttt atcaaaataa
     8101 aatatgacct taatttagaa atctgatata ataaaaatta aatacatata agggggtaaa
     8161 catgagaaag tataaatcaa aaaaattgtc aaagctacta gcattgttga cagtttgctt
     8221 tttaatagtg tcaacaatac ctgtctcagc agaaaaccat aaaactctag atggagtaga
     8281 aactgcagag tattctgaaa gctatcttca atacctagaa gatgtcaaaa atggagacac
     8341 agcaaaatat aatggagtaa taccttttcc acatgaaatg gaaggtacaa cacttcgaaa
     8401 taagggtaga agtagtcttc catcagcata taaatcaagt gtagcataca acccaatgga
     8461 tcttggtctt actacaccag caaaaaatca aggaagtctt aatacatgct ggtctttttc
     8521 aggtatgtca actttagaag catatcttaa attaaaagga tatggaacgt atgacttatc
     8581 agaagaacat ttaagatggt gggcaactgg tggaaaatat ggatggaact tagatgatat
     8641 gtcagggagt tcaaatgtaa cagccatagg atatctgaca gcatgggcag gtcctaagtt
     8701 agaagaggac ataccatata atcttaaatc tgaggcacaa ggtgcaacta aaccttcaaa
     8761 tatggatact gcacctactc aatttaatgt aacagatgtt gttcgtctta ataaagataa
     8821 ggaaactgta aaaaatgcta taatgcaata tggttcagtg acatcaggtt atgcacatta
     8881 ttcaacatat tttaataaag atgaaacagc atataactgt acaaataaga gggctccatt
     8941 aaatcacgct gtagcgatag taggatggga tgataattat tcaaaagata actttgcatc
     9001 tgatgtaaaa ccagaatcaa atggagcatg gttagtaaaa agtagttggg gagagtttaa
     9061 ttctatgaaa ggattcttct ggatttctta tgaagataaa actctactaa cagatacaga
     9121 taactatgca atgaaatcag tatcaaaacc agatagtgat aaaaaaatgt accaacttga
     9181 atatgctggt cttagcaaga taatgtcaaa taaagtaaca gcagcaaatg tatttgattt
     9241 tagcagagat tctgaaaaac ttgactctgt tatgtttgaa acagattctg taggagcaaa
     9301 atatgaagta tattatgcac cagtagtaaa tggagttcct caaaacaatt caatgacaaa
     9361 acttgcaagt ggaacagtat catattctgg atacataaat gtacctacta attcttacag
     9421 cttaccaaaa ggtaaaggag caatagtagt agttatagac aacacagcaa atcctaatag
     9481 agaaaaatca actttagcat atgaaactga tatagatgga tactatctat atgaggctaa
     9541 agcaaactta ggtgaaagct acatacttca aaacaataaa tttgaggata taaatacata
     9601 tagtgaattt tctccttgta actttgttat aaaagctata acaaaaacat cttctggaca
     9661 agctacttca ggagaatctt taactggagc agatagatat gaaacagcag ttaaagttag
     9721 tcaaaaagga tggacttctt cacaaaatgc agtattagta aatggagacg caatagtaga
     9781 tgctttaaca gctacaccat ttacagcagc aatcgactct ccaattcttt taacaggaaa
     9841 agataactta gattcaaaaa ctaaggcaga gttacaaaga ttaggaacta aaaaagttta
     9901 tctaataggt ggagaaaatt ctttaagcaa gaatgtacaa actcaactta gtaatatggg
     9961 tatatcagta gaaagaattt caggtagtga tagatacaag actagtatat ctctagctca
    10021 aaagttaaat agtataaaat ctgtttcaca agttgcagtg gcaaatggtg taaatggact
    10081 tgcagatgca ataagtgttg gtgcagcagc tgctgataac aatatgccaa taatacttac
    10141 taatgaaaaa agtgagttgc aaggtgctga tgagttttta aattcatcaa aaataactaa
    10201 gtcttatata attggtggaa cagctacttt atcatcaaat ttagaaagta agctttcaaa
    10261 tccaacaaga cttgcaggaa gtaatagaaa tgaaactaat gctaagataa tagataaatt
    10321 ctatcctagc tcagatttga aatatgcttt tgttgttaaa gatggttcaa agagtcaagg
    10381 agacttgata gatggactag cagtaggagc attgggtgct aaaactgatt caccagtagt
    10441 tttagttgga aataagttag atgaaagtca aaaaaatgta cttaagtcta agaaaataga
    10501 aactcctatt agagttggtg gaaatggaaa tgaaaatgct tttaatgaac taaatactct
    10561 tttaggaaaa tagtgaatgg aaagatagta aggatataca ttttattatt aaaaaatgtt
    10621 caatagaagt ttataaatat aaaataacaa aaaggggtgt ctcaaaatga actttttagt
    10681 tcatgaggca ctcttttttg ttgttttata tttttatcat ttaaataatg aaaaataaga
    10741 ttgtctatat ttttagatag ttttcttatt attgatgaaa aatgtaataa ttttaaactg
    10801 taaaatagtg taaagttatt ttataatata aatatagtaa gattttaaac aaaataaggg
    10861 ggaataataa tgaaagcacc aaaaactatt ttaacaatac tgacaatagc gcttacttta
    10921 agtagcattt ctataatacc atcatatgca cttacagagg aaaaattaat aggtaatggt
    10981 agatatgaaa ctgctgtaaa gataagtcaa aaggcataca gttctagttc taatgtagta
    11041 ttagttaatg acaattcatt agctgatgca ctttcagcta caccatttgc aaaggctaaa
    11101 ggagcaccaa tacttttgac agaaagtgat aagctagatg ataggactga aaaagagata
    11161 aaacgtctag gagctaaaga tatttatttg ataggaggta ctgctgtact taataaagat
    11221 atagagaaca agttaaaagg taatggactt aatgtagaaa gaattaatgg taaggataga
    11281 tatgaaactt cactgatttt ggctaataag cttaaggata taaaagatat taaggaagtt
    11341 gctgtagtaa atggtgaaaa aggattaagt gatgctgtta gcgttggagc accagcagct
    11401 caaaataaga tgcctataat tttgtctagt cctaaggacg gagtagaagc atttgataaa
    11461 tttataaggg atgagaaagt tataaaagca tatgtaattg gaggaacaaa ttctgtttca
    11521 agagctgtag aaaagagtct tcctaatgca gaaagagtga gtgggaaaga tagaaatgag
    11581 actaatgcta aggtcataga aaagttttac actgatacaa atttaagtaa tttatatgta
    11641 actaaggatg gtagtaaaaa tgagaatcaa ctaatagact cgttagctgt tggagtattg
    11701 gctgcaaaaa atgagtctcc tgttgttttg gttggtaata aattaaacac aaaacaaagg
    11761 gacatactta gtactaaaaa attaaatact ataacacagg taggtggaaa tggaaatgaa
    11821 gaagcttttg atgaaattaa aagtctacaa gaaaaaactg tgtttgaagc aaaaactgtt
    11881 gaggaattaa ctgatatgat aaatatagca agtcctaatg atattataaa ctttaaacca
    11941 aaagagaata ctgtaaatga agcttttaga atggtaacaa ataaaccaat aactgtgaat
    12001 ataaagggtg attgttcaaa gactcttaca gtagatatgc ctaatggtga agtgaataac
    12061 tatgctactt tggtaaatgt tatagttaga aatattggag aaggtggatt taataatcat
    12121 gatacaatca ctatattgtc agttcgtgac aaaaatggta gagttataga aaatactaga
    12181 aattcagata tagatacgtt gatgatatta gcttctgcta atgatacaaa attgattaat
    12241 gatggatata taggaaaact tatagataat tcatctaata gtgatataac taataatggt
    12301 actatagata aaaaagttaa tcaggttgaa gatttagagg ctaaagtaga ttcaattgaa
    12361 aaagctatag attctataag tcaaaaagtc aataaaatac aagatatact agataagctt
    12421 ggatttctaa agaaatttct tagctaagaa tatatatatt taagtgaagt gtgtgttgta
    12481 attgttctaa agttatgtag ttaaacaggt ttatatacaa atagatttat agataaatat
    12541 gcagttcagt atatatttga ataagctttg gggaggtaac atggggattg gaattgaatg
    12601 taacaaaaaa ataaataaaa gtattgacaa aactagaata aagaaaaata atct
//
LOCUS       DAEQAF010000104        12493 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.107, whole genome shotgun sequence.
ACCESSION   DAEQAF010000104 DAEQAF010000000
VERSION     DAEQAF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.107"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            142..330
                     /locus_tag="KRN00_003072"
     CDS             142..330
                     /locus_tag="KRN00_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828924.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTRFKNII
                     EVMYISKSLIMDEISKRD"
     gene            590..1789
                     /locus_tag="KRN00_003073"
     CDS             590..1789
                     /locus_tag="KRN00_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBH1828925.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKNIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAISLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            1841..2344
                     /locus_tag="KRN00_003074"
     CDS             1841..2344
                     /locus_tag="KRN00_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1828926.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            2451..2768
                     /locus_tag="KRN00_003075"
     CDS             2451..2768
                     /locus_tag="KRN00_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828927.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            2926..3885
                     /locus_tag="KRN00_003076"
     CDS             2926..3885
                     /locus_tag="KRN00_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1828928.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIIASKLLIGLYE"
     gene            4000..4785
                     /locus_tag="KRN00_003077"
     CDS             4000..4785
                     /locus_tag="KRN00_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828929.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            5077..6396
                     /locus_tag="KRN00_003078"
     CDS             5077..6396
                     /locus_tag="KRN00_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBH1828930.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(6471..6899)
                     /locus_tag="KRN00_003079"
     CDS             complement(6471..6899)
                     /locus_tag="KRN00_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828931.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(6990..8366)
                     /gene="hydG"
                     /locus_tag="KRN00_003080"
     CDS             complement(6990..8366)
                     /gene="hydG"
                     /locus_tag="KRN00_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBH1828932.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIREEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(8367..9452)
                     /gene="hydE"
                     /locus_tag="KRN00_003081"
     CDS             complement(8367..9452)
                     /gene="hydE"
                     /locus_tag="KRN00_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBH1828933.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(9488..10696)
                     /gene="hydF"
                     /locus_tag="KRN00_003082"
     CDS             complement(9488..10696)
                     /gene="hydF"
                     /locus_tag="KRN00_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBH1828934.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(10711..10962)
                     /locus_tag="KRN00_003083"
     CDS             complement(10711..10962)
                     /locus_tag="KRN00_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBH1828935.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(11343..12383)
                     /locus_tag="KRN00_003084"
     CDS             complement(11343..12383)
                     /locus_tag="KRN00_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBH1828936.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
BASE COUNT         4612 a         1529 c         1892 g         4460 t
ORIGIN      
        1 attaaaatat gtaatgtcac tgatagttag aatatttaag tgctaaaaga tgtgtataaa
       61 taataatgat gtcagtttat aatgatatta aattgaggta tactgtttct ctaaattaaa
      121 aaataaagga gtaaatgtgt tatgaattat catacaaaag aagaattggt ggaagcactg
      181 agagtagtat cttcaagtat tattaattgt ggaaaaggac agaagaaatt ttctgaggag
      241 acatctcatc atacacgttt taagaatatt atagaagtaa tgtatatttc aaaatcatta
      301 ataatggatg aaattagtaa aagagattga agcttatttt gcaatttaac atgttttaat
      361 atacatttta ttatataaga aaataagtaa acatacatgt tataaaatat tgaaataata
      421 tacaattata aatttgttaa cattaatatc tatatgttaa aatatagtag aagatgttag
      481 taaataatag gatgagttct attttaatac aattaaatta agcttagttt gaaatttgta
      541 tctaaaaagt aaagtaatct agaattaaga aaatggagat agaattataa tggaaaaatt
      601 atattataca aatcagtata taagagattt tacagcagaa ataattgaaa taaaagaagt
      661 agaaaataag tatcatgttt tattagataa gacagctttt tttcctggtg gaggaggtca
      721 gtttggagac ctgggaaaaa tagagaatga tgatgtaata aatgtgtatg aagatggaaa
      781 aaatatatac catgtattag ataaaaaacc tataaagata cataaggtaa agtgtagtat
      841 tgattgggat agaagagaag atggaatgca tcaacatttt ggacaacatg tattgtctgg
      901 atgttttttt aaaactttta atgcaaatac gacaggtttt catttgggaa atgagtatag
      961 tacagtagat atagaaggta atttagaaga ggataaaatt agagagatag agttgtttgc
     1021 caatgaaatt attcgtcaaa atatacaagt agagacatta cttccaacga aaaaagaact
     1081 aaaaaagatt tggttaagac gtgatttgcc aaatactgat gaagagataa gagtaataaa
     1141 aataggtgat ttagatacga atgcatgttg tggagtgcat ccaaaatcaa ctggtgaatt
     1201 gagaatgata aaaataaaga aatgggaaaa acataagtca agtacaagaa tagagtttct
     1261 agcaggtaaa agggcagtgg atgaagtatt gaagagggat atatatttga ctaaaatatg
     1321 tagatattta agctgtagtg aggaagatgc tataaatggt attgtaaatc taaatagtaa
     1381 agtggaagag gctttaatta aaaaaagaag gcttgaagaa gtagtatcta catatcaggt
     1441 caaagaaatg attgaaaaag caaataaggt tggcaatatt tcggtcatta aaaaaattta
     1501 tgatgatgaa gatttgaaat atgtaaataa gatagcaaat aaaattgcag aatatgaaaa
     1561 tagtattgca ttattagctg ttaaatttaa tgataaaata aatttagttt ttgcatgttc
     1621 taaaaattta aaagatatta atatgggagt tttattaaag gatgcaataa gtcttataga
     1681 tggcaagggt ggtggaagta aagtattagc tcaaggagga ggtaagaata atggaaattt
     1741 agaggctaca cttgattatg catttatgaa gatagaaaaa actctataaa tatattatat
     1801 aaaaaacctt agtagataaa atagatatgg aggaataagt atggagcaac aaaaggacta
     1861 catagagtta tatgaaaatg aagaactaat agagataaga gaagcacgta tggatgattt
     1921 ggatacaata gcaaaattta attataattt ggctaaagaa actgaaggaa aagaacttga
     1981 tatggatgtt ttaactaaag gtgtaaaagc attgttatta gatgagagaa aaggaaaata
     2041 tcatgtatat acagtatttg ataaagttgt tgcacagatt atgtatacat atgagtggag
     2101 tgattggaga aatggaaatt tcctttggat tcagagtgta tatgtagata aggaatatag
     2161 aagaaaaggt atctttaatt atttatttaa ttatataaaa aatatatgtg ataaagatga
     2221 aaatatagtt ggaatgagat tatatgtaga aaaagaaaac ataaatgcaa aagcaacata
     2281 tgagtcttta aatatgtatg agtgtgatta taatatgtat gaatacgaag taatacattc
     2341 gtaatataaa tttgtaatac tgttatactg atgttataaa gtattgatta tattgacgat
     2401 tatatgaaat aaactggata ttataattag aatttttagg gggtataaaa atgggcgttt
     2461 taaaaggaat gttttatgta tttttatttt tagatttagt gtcaatattc tgtttctttt
     2521 ttaataaagg aaaaatagca tctaataaaa ttgtgtttaa tgcaatagga gtacttacat
     2581 ttgtactttg ttttatgctt tttagttatt atcctaataa taatcttatt ggaaaattta
     2641 ttgcttctct attttttata tttggagttg caggagttat gttgaaagaa aaaaattttt
     2701 tatatgctag acttctttta actgtagtta tagttttttc tacattaaga ttgttcgtta
     2761 ttcaataaaa tgtatttgta tgaaaattta ttaaagtcta cacatttaag tgtaggcttt
     2821 tttgattttt tgtttgaaaa ttaaggaaat tttaaggaaa ttttaaaatc gtcttaaata
     2881 tttattgata tacttaaaat attaatagcg aaaggagact tatcagtgat agaaagtaaa
     2941 aagtcagaaa aattgttact gtcaattata tacataatat ttttggtata tattttaatg
     3001 attataagaa taattttatt tagagatgta ccaatttacg ctattttcaa gggaacgttt
     3061 aggaatgtaa atttaattcc attttataca atatatcaat ttatagtaga tagtaatctt
     3121 gactttatga aagctactgt aaatattata gaaaatatag gtatatttat tcctatggga
     3181 atttttttac ctatagtatg taaaaatcta aataaaaaaa ctataattat agtaattata
     3241 cttgttagcc tagcatttga attaacacaa tatatttttg ctcttggaag tagtgatata
     3301 gatgatgtta ttttaaattc attaggtggc ataattggaa ttaatattta cataaacatg
     3361 aataaattat ttcccaatga tattaacaga tttaaggcta taataggtac tagtttagtt
     3421 ttaggagtta taggattagg agttatttct aaaaattatc ataacttact aacttttaaa
     3481 tttagacctg atagaaaaat atcaaaaata ttaattgaag aaaataggga aataattaaa
     3541 gatataaata aagatacagt agatatagtt gggacatttg agagctttaa aaaaggaata
     3601 ataactatta aagcaggttc taataacaaa gtaaagagac cagagaattt aattgattct
     3661 gatggaaata taagaattta tttaaatgaa aatacaaaat tagtatctta tataattacc
     3721 aaagaatcaa aaatggatat agttaaatat gaggaatttg atgtgaagaa tttagattta
     3781 ttaaggagat atgatactat taatgtttgg attgataaag aaaatcagcc aaaggataaa
     3841 catggtatta tagctagtaa attattaatt ggattgtatg aataaaatat taaacaagaa
     3901 taaaagaata acaaatataa aaaacgaaaa aactatttct ataattattt ttacgttgtg
     3961 cataaaataa gaacattagt gaaggagtag agataaatta tggagataat aaaatatatc
     4021 ttgtactttt ttatatattc atttttagga tggacagtag aaagtatagg atgttctata
     4081 gcaagcaaaa gaataatcaa cagaggtttt ttaaatggtc caatatgccc tgtttatggt
     4141 tttggagcgg taattgtgat atcactattg ggaagattta ataatgtagt aatagtattt
     4201 ctattaggaa tgattttaac tacgatacta gaatatttta caggatttat tttagaaacc
     4261 ttatttcatg ctaaatggtg ggattattct gacagaaaat tcaatataaa gggtagagta
     4321 tgtttaaaaa atgcaatata ctttggtgta atgtctgttt taataataag atttatacat
     4381 ccatttataa aatattttgt aagtataatt ccatatagaa tattaatttc aatggctata
     4441 attacaacac tttggactat acttgatttg attgttacta ttataacact taaaaaatta
     4501 gatataaagt taaacttact agacgatata attacagacc ttaatgatat aaatgtgaaa
     4561 ttggataaat ttgatagagg agaaatacaa gctttattta aaacaataaa taacgacgaa
     4621 ttagaagtta gagaaaaaat aaacaaaata aatagtaagt tggaccgtat agagtctaat
     4681 attattttac aaaaaagagt tataaaagct tttccacata taaaacataa aaaacaacaa
     4741 gagcaactag aacattttaa aaaaattatt aatgagaaaa ggtaattata caatttaatg
     4801 aagacgaata gaataatggt atttataaga tgattttcag aggactctat aaaaatagaa
     4861 tagagtcctt tattttttga aaaataatgt ttatttgata aaaataaaat atattgtttc
     4921 tgaataacaa atattttgaa aattataaaa acatatattg acaatttgtg tcaaaaatac
     4981 taacattaag tatataaaga attttatatg agaatatctt tataaatcgc aataatttta
     5041 aaacataaat ttatttaaag aggggatgat ttgccaatga gcgagataac tagtcaaatg
     5101 ataagtacag aagaaaaaaa atatgttgct aaaactcaaa agatacctta ttatccagta
     5161 gcatttaaat caggtgatgg tgcaatgcta tatgattatg aaggtaatga atatgtagat
     5221 tttttagcaa gtgcaggctc tgcaaatgta ggtcatggta ataaggaaat ctcacaagca
     5281 gttaaagaac aaatggatga tataacacaa tatacacttg catatttcca tagtgatcct
     5341 cctgtaaaat tagctgagaa gcttgtggaa atagcccctg gagataatga taaaaaagta
     5401 ctatacagtg caactggttc tgcttgtata gatgctgcta taaaattagc aagaggatat
     5461 actggaagaa caaagataat atctatgtgt gaatcttatc atggaagtac ttatggagct
     5521 atatctatat ctgctttaag tacaaatatg agaagaaaaa tgggtccatt gttaccagaa
     5581 gtttatcact tccattatcc tgataaaaat agaacagcta aagaatgttt agatgagata
     5641 gaatatgctt ttgcacacta tctaccagca gaagaggtag ctgcaatatt tatagagcca
     5701 attgcaggag atgcaggaat aatagtgcct ccagtagagt gggtacaagg tttaagtaaa
     5761 atatgtaaag aaaatggaat attacttgta agtgatgaaa tacaacaagg tatgggaaga
     5821 acaggtaagt ggtttggtat agaaaatttt ggtgttgaag cagaccttat agttcttgga
     5881 aaatctgttg gaggtggatt acctctagga gcagttgttg gaagaacaga aataatgcaa
     5941 agtcttgatg caccagcaca tttatttact ttagctggaa acacaacagt atgtgtggct
     6001 gctttaaaat ctatagagat aattgaaaaa gaaaacttac ttcaaaagag tatagaaatg
     6061 ggagattata ttaaagcagg atttgaaaaa ctaaaagaaa aatacgatat aattggagaa
     6121 ataagaggca taggattatc tataggagtt gatatagtta aaggaaaagg ttctaatgaa
     6181 aaacatccag atgctacagc taagatatgt tatagatgta tacaaactgg attaataatg
     6241 atattcttag gacaatctac tttaagagtg caaccacctc tagtaataac taaggagcaa
     6301 gtagataaag caatgaacat catagattct gcaatagatg attatttaaa tggtagaatt
     6361 ggtgatgaag tatatgaagt aactcaaggt tggtaaaata aatattaaat gaaaatagga
     6421 gttatctcaa ttttagaaaa ttatttctga aatgagataa ctcttttaag ttacccacaa
     6481 ataagaaaat tgtttgattc attaaagact atatttcgga tgtcgttttt gtgagtatca
     6541 gagacagtat tacgagaata attaccttta ttcgtactat ctgttaattt agttataatt
     6601 aagatagcta aaagaataag aattactgtg tataaagcaa taacatatgg ttttctttta
     6661 tatttgtatt tgttattgaa aaaagaatgg ccataattat ttttatttac tttagatgta
     6721 tttgtattct ttttcttgtt acctttcttt ttatcatcct tttttctatt tttagggtaa
     6781 ggaatgactt tgtgtgtatt atcaagtttg atatttttat ttttttgaat attgttttcc
     6841 aggctagcct ttttttctcc aaattgaata gttttattgg tattgttgtt atctttcaat
     6901 gttaatctcc ctcccttaaa ctttcccttt agataatatt actactaacc tatggaatat
     6961 acaataaata atatataagt aataaaattt tataggtata aatctctttc tccacgctct
     7021 aaggcagtca tattgttaga tactatgttt cttatatctt ctctttctat cttacctatt
     7081 tcttctgcga taagtttttt acccataatt ttaagttctt catctccata atcgattaaa
     7141 aattcattta atgtagtaag agcatttggt gtacatacat tatggatttg tcgactttta
     7201 gctaagctca tgaatctatc gccagttcta cctttacgat aacaagctgt acaataacta
     7261 ggtatatatc catcagtaat cagttcttta agcacctcaa cagggcttct atggtctcca
     7321 acttcgaatt gttctgtatt gtcaccatct tcatatgctt tatatcctcc aacacctgtt
     7381 agagaacctg cactaatttg tgatacacca tattttagta actcatttct catttcagca
     7441 gtttctctag tggacattat gattccagta aaaggaacag ctaatctagt tatagctact
     7501 atttttttga acatatcgtc agaaactaag tgaggaaaat cttctaagct cataccttca
     7561 gcttttttca atctagggaa agatatagta tggaaaccta caccaaattt ttcctctaag
     7621 tgttcgttgt gcatcataag tcctagaact tcaaatttag ggtcagataa accaaataaa
     7681 actcctgcac caacatcatc aacaccagct tccatagctc tatcaaaagc tgttaaatgg
     7741 taataatagt cattttttat agattgacca tgcattttta taaatgttgg tttgtgataa
     7801 gtttcttgga ataatatata agttcctatt cctttttctt ttagtaattt atactcatct
     7861 acacttgtag ctgctatgtt aacgtttacc cttcttatat ttccgttttc attatatgtt
     7921 gaataaattg catctaagca atctaagatg taatttatat cacaattttt agggtcttca
     7981 ccagcttcta gagcaagtct tttatgaccc attttttcta atattttaac ctcttccctt
     8041 atctcttcca tggtaagttt ttttctttta aatttgttgc atttactaaa accgcaataa
     8101 acacattcat ttacacagta gtttgataca taaagagggg caaataaaac cactctatta
     8161 ccatatattt cattttttat ttgcccagct atactaaata atctatctag ttgtttttta
     8221 tcttctactt caagaagtgt agctatatct ttataactaa gtttttccct tctatcagcc
     8281 ttatcaagta ccttttcaat atcatcagaa gttgaatttt ttgcatcttc taataaagaa
     8341 ttaataagtt catggtttat gaacatttac aaacgcctcc attcaatatt atcaccgcga
     8401 gaatagtcaa cttcaagtcc taatgacttg atgttttctt ctaaactttg gtgatattca
     8461 caagcttctt gaccagtaaa ggctttgtta tcgtaaagag aatattgttt tctaaattct
     8521 tgaggagaaa ggtttggcat aattacattg caaccagcta aaagacctgc atttctacca
     8581 ctagggttta tagatgccaa ggctgttgta gcgggtaata aaacttttgg aagtagaagt
     8641 cttgtaattg aaagcataag taatgtcttc tctaaatctc catgtttata atccttaaaa
     8701 attgtatcat ggtgtggaat gaaaggtcct attccaacca tatgaggatt taactctttt
     8761 aggtataata aatcacgaac aaggtcttcg ttgttctgaa atggtgattc aaccataaat
     8821 ccagcaccta cctgataacc aatttcttta aggtttttta ggcattcttt tctagttcta
     8881 agctcaatgt ttggcggatg taatttttta taatgactgt ctgtagcagt ttcatgtctt
     8941 aaaagatatc tatctgcacc acataaaaag tattttttat acgaatcata actcttttct
     9001 cctagtgata gagttatggc acaatcctca tatttatttt ttatacttga aacaatttca
     9061 catattttat catcagtaaa atatgcatct tcaccacctt gcaaaacgaa tgttctgtat
     9121 cctattttat aacctatatc acaacattca agtatttcat caagtgaaag cctgtatctt
     9181 atgatatttt tattagaaga ttgtattcca caatagtagc aattattttt acaatagttt
     9241 gtaagctcta taagtcctct caagtagact ctatttccat aatgtttatt tctcatgtcg
     9301 ctagcttgtt tataaagata gtttcttaaa ttttgttcga agttatattc ctcattgtcg
     9361 atattttcta ttaaatatag tagttcatca aaacttaatg aattaatgct gtaaagttta
     9421 tctataaagt atttaatctt atttttagtc atattcaaat atgtaattat taagtatagt
     9481 taaattttta ataattgaaa agttcaagtg atctttccaa aatacctttt acatatgcta
     9541 ttaagacacc atagtttaca ataggtacat tgaaagattt tgccttttct attctagata
     9601 acattccagc tctattcatc atacaagctc cacagtgaac tacaagggca tatttattta
     9661 tatcttcagt gaaggatact ccagaactaa attcaaaagt aatgtttttg ccagttttct
     9721 ttctaatcat attaggaatt tttactgttc caatatcatc agtttgtcta tgatgggtac
     9781 atccttcggc catcaagatt ttatcaccat cttttaaatt ttctaaagca taagctccat
     9841 taatcaattc tttaaggtct cccttttgtc tagcaaacaa tatagaaaaa gatgtaagag
     9901 gaatatcttt tggtgtatct ttatctactt gtggaaatac ttgagagtca gtaataacaa
     9961 gttttggttt tttgcctaaa ttagatagag tttcttttaa actatcttct tttgtaacta
    10021 tagaaattgc accattatcc aaaatatctc ttataacttg ctgttgagga agtataagtc
    10081 taccttttgg agctgcttta tctattggaa caactaaaac aactaaatca tttggttcaa
    10141 ttaaatctga taccaatttg aactcagtgc tatccttagg caaaactttt attatttcat
    10201 tttttaaatt ttcaattcca attttatctg ttgatgagac agaaacaact ggacatttaa
    10261 ctttattttt agttaagttt aaaatttctg attgattctt aatagtatca attttgttga
    10321 gaattagaat atgagggata ttcttatcat taaatttttc aattagtgac aaatcttctt
    10381 gtgatatacc aatttggcaa tccactacta gtaaagctat atctgtcttt tctaaaacat
    10441 ctagtgattt acctattcta agttcaccaa gttcaccaac atcatcaaga ccagcagtat
    10501 ctataagaac acaaggtcct ataggaagga tttccattgg tctaaatact gggtctgtag
    10561 tagttccagc aatatctgag actattgcag cactttgatt tgttatagca tttattatgc
    10621 tagatttacc tgcatttctt ttaccaaaga gacctatatg tactcttacc gattgtggag
    10681 tagaatttag actcatttgt actcaccacc ttaaacttct ttttttgata tactagtttt
    10741 tacagataca tgaggtatgt tgcctaattt accagtcaaa ctattaatag tatccatttc
    10801 gccaacaact gctatacata cgattgagac accttcttct tcgcaaggaa tgcccattct
    10861 tcctttaata atacctttaa aacctgatac aacctcattg aatttaaatt gacattcttt
    10921 tggctcttcc aaaatagcac ttataactgc aacctttttc ataaatatcc tcctaactca
    10981 gaaaatatgt cttaaacaaa tccaaaatca aaaaactttt ctttgtaaag aaaagtttct
    11041 acaaaagaaa agttattaat tacacaagta taatgtgcta tattaaacta tttccttaca
    11101 gattagataa ctcttttctg gtagggttag cttgtaaaaa tttaatttaa caacaagtaa
    11161 ctgaagaaaa tttttataca atttatataa attataataa aaattaacta aagaaaattg
    11221 aagttactta tataatagta gtaaattgaa attaagtcta tagaaaaacc aatttttgta
    11281 taaaaataaa aattaaagtt aattatttgt taagaattga ctttggtaaa atatataatt
    11341 aattattctt taagcatata atttataagt aattttagtg tattttcaat agcttctata
    11401 tgtgttcttt cataatggtg actattgttt gttccaggac caacacatgc tatttgaaca
    11461 tcttctcccc aacgaatagc ttctgaagca tctgaaccat agaaagtaaa tacatcgaca
    11521 gcgtagtcta aattattgtc ttctgcaaca tcgacaagct tgtttcttaa attaaaatca
    11581 tataatgata aattatcttt tgcaactata gttacaccat gttcactaga tgtttgactt
    11641 ggtccagtag gtgctatatc tattgctaca aattcttttg ttttttcagg taaacattta
    11701 gaaacaccat gtccaatttc ttcataatta cttatataaa agttagtagt atgcttaggt
    11761 gttaaattgt tttctttaaa atatctacat atttcaagaa ccattgctac agctgattta
    11821 ttatctatat atctagattt tataaaacca gattctgtag cctcaaatct atggtctagg
    11881 catacaaaat ccccaacact tattcctaaa tctaatacat cttgctttgt aaatactttt
    11941 tcatcaagtc taataatcat tgtttcttca tttctttcag tggcagcttt tgtttgacca
    12001 tatatatgag tagaagcata cttaaataca acacttcctc tgattttttt accttttcta
    12061 gttataacag tacagttttc tccctctata gctgcccaac atccaccacc aactttatgg
    12121 tatttaagag taccatcaga tgatatttct tttactatag ctccaagtgt atccatatgt
    12181 gcagatattg ttatttgatt tgaatcatct tcaccaggaa gagtagctat aagtgcacct
    12241 ttttttgtaa gaatagtgtc aagacctaaa ttttcaaaat cttttttgat ttctaaaact
    12301 gcattttcag tatatccagc tgggcttgga atgtccaaat attttttcat taaatttata
    12361 gtattagtta aatttaaatt catattgttt cctcctaaat aaatatattt atacaaatta
    12421 taacataaat acaaatgttc tgaaaactaa aattaaaaga atagaatcta aacatattta
    12481 aaaaaaaagt ata
//
LOCUS       DAEQAF010000105        12390 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.108, whole genome shotgun sequence.
ACCESSION   DAEQAF010000105 DAEQAF010000000
VERSION     DAEQAF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12390
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.108"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            133..1014
                     /locus_tag="KRN00_003085"
     CDS             133..1014
                     /locus_tag="KRN00_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBH1828937.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(1075..2283)
                     /locus_tag="KRN00_003086"
     CDS             complement(1075..2283)
                     /locus_tag="KRN00_003086"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBH1828938.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(2356..2608)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(2760..3749)
                     /locus_tag="KRN00_003087"
     CDS             complement(2760..3749)
                     /locus_tag="KRN00_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBH1828939.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVIGLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            3901..4341
                     /locus_tag="KRN00_003088"
     CDS             3901..4341
                     /locus_tag="KRN00_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1828940.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGFICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            4668..4895
                     /locus_tag="KRN00_003089"
     CDS             4668..4895
                     /locus_tag="KRN00_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBH1828941.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            4921..7041
                     /gene="feoB"
                     /locus_tag="KRN00_003090"
     CDS             4921..7041
                     /gene="feoB"
                     /locus_tag="KRN00_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBH1828942.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKEDQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(7174..7992)
                     /locus_tag="KRN00_003091"
     CDS             complement(7174..7992)
                     /locus_tag="KRN00_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1828943.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIVGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            8199..8483
                     /locus_tag="KRN00_003092"
     CDS             8199..8483
                     /locus_tag="KRN00_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828944.1"
                     /translation="MLVRVKIVIGATIRYLIKHKVNYCNKKSLDKLELKYGNIDREKA
                     VKLEIFYQYLIELEYIEMSLLIRRLDTAITSLALVSIITIASYYLIRKNV"
     repeat_region   8583..9272
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=8718..8746
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(9930..12023)
                     /locus_tag="KRN00_003093"
     CDS             complement(9930..12023)
                     /locus_tag="KRN00_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1828945.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLVYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
BASE COUNT         4429 a         1803 c         1478 g         4680 t
ORIGIN      
        1 tgcaaataat gtcatataag ttacacttta gttatcttag ttacaacttt gtcggtttac
       61 tttttctact ttcttcgata taattataat atatttttga tacaattcga caaaaggggg
      121 aatgctgtaa ttatggtaaa aaaaagaaaa aagaaaactg ttacacttac tatacttgtt
      181 gtaatagtta ttggtatttt ttctatggca tgggcggaca tgtctagaaa aaaagaaatg
      241 aaagaaactc aagaaagact taaagctgaa agattagaaa aagaaagaat tgaaaaagaa
      301 aaaaatgaac ctattattgg tgcaaaaaaa gaagctgtaa aagaatatgg atatgacgca
      361 aaaatagttt gggacaaact taacaaatac gactattcaa acaatggaga aaagatagtc
      421 tttcttacat ttgatgatgg accatctact actaatactc cacaagttct agatatcttg
      481 aaaagacatg gtgttagagg aactttcttt attaagggtg attctcttga aagaaaagga
      541 gctaatgaaa ttttaaaaag aacatttgac gaaggaaatg caatagccca tcactcttat
      601 actcatgact ataaaaaact atatcctaac agaagcctaa atctcgatac attcgtaaat
      661 gaacttaaca aaactgatga agctatgaaa aaagtcttag gaaagaattt ttcctcaaat
      721 gtagttagat gcccaggcgg gtatatgtca tggaaaaata tggaacctct aggaaactac
      781 ttaaaagaga aaaacatggc atcaattgat tggaacgctt taaatgctga tgcagaaggt
      841 aaaaagaaaa atgcacaaga attatttgaa catgcaaaga aatcttctga aggcaaagaa
      901 atggttgttc ttttaatgca tgatacttat ggaaaacaag aaacagtaaa tgcattggac
      961 caaattataa catattttaa agataatggt tatcaattta aaattttaat ataataaaaa
     1021 agcaagttta ttgaatgtac attttatact caatagactt gcttttactt tactctattt
     1081 tactagctcg atttttacaa attttttctt tcctatttga acaactaatt cactctcttt
     1141 tacaatagtg cttaaatcct ctactttttc accatttacc tttactccac cttgagaagc
     1201 taatcttcta acttcactct tactcttaac aatctcatta gaaactagta cttcgattaa
     1261 gtcaaatcca tcttccttaa cttgaattgt ttgtatatct tcaggtattt gacctttttg
     1321 gaatacagat ttaaatcttt cttcagcttc tttagcagat tcttctccat ggtataatgt
     1381 tactatttct cttgctaagt tcatctttat atctcttgga tttactgaac cctctttcaa
     1441 ctgagattct attttattaa cttcatcagg atgaacatct gtcactaaat tgtagtattt
     1501 aattataagt tcatcaggaa tttccataga tttttggtac attattcccg cttcttcatc
     1561 tattccaata tagttaccta aactcttact cattttttct ttaccatcta atccttctat
     1621 taaaggcatc attattacta tttgagactc cataccaaat tctctttgta atgatcttcc
     1681 cattagtaaa ttgaatcttt ggtcagttcc accaagttct atatcagctt ctaatgctat
     1741 agagtcatat gcttgcatta atgggtagaa gaactcatgt actgatattg gcatttgtcc
     1801 ttcatatctc tttttaaaat cttctctttc taacattctc gcaacagtaa tagttgctgc
     1861 taattttatt acatcttcaa aatttaactt agctaaccac tcgctattaa atcttacaat
     1921 agttttttct ttatctaaaa ctttgaaaat ttgttcttca taagtttttg catttgcaag
     1981 aacttgctct gttgttaaag cttttctagc tttagatttt ccagttgggt ctccaatttt
     2041 tcctgtaaaa tctccaatta ttattactat ttgatgacct aaatcttgta attgtttcat
     2101 ctttctaaga actactgtat gccctaaatg tatatctgga gcacttgggt ctagacccaa
     2161 ttttactatc ataggttttc cttctttttc tgatttaata agcttttccc ttaactcttt
     2221 ctcatctatt aaatcatcta cacctttcat aattattcgc atttgctcgt ctatcgattt
     2281 catttttcat tcctcctaaa atatttatat aatctataat ttttattttt ataataaaaa
     2341 aagctttcat cctcttaaaa ggacgaaagc attgcttacg tgttaccacc ttagttcatc
     2401 aatatctcac gatattaatc tcttagagta caattacata tactcgtgta ctataacgtg
     2461 tactaatccg atatctctta atggttgtta tctttcagag atagtgctct gagatgtatt
     2521 caaactaaat caatttattc catttcacca aactggaact ctctgttaaa taaaatctag
     2581 ccctacttct tctcttcata gcatttatat attcagatta tttcatcaat tacaagaaat
     2641 ttttcttaac ttactcataa tatattatta tttttatatt ttgtcaacct tttttattat
     2701 tatatacatg tttttttaca ttatactact tttttatatt ttttaccaat acccaaaatt
     2761 tatttttcaa tcaaaagatt tatttgttta ttgactatat tactctgact caatcttata
     2821 tttattttct tatttaaaaa tgcgtttata attattaaac caataactgt tacatcaaat
     2881 ataaaaaaca gcaataaaat tattatcaaa aataaaattc tagcatataa taattttcta
     2941 aacttagcta ttataaagtt ttgtagtgac atacatgagt ctctaatgat aaaatagaca
     3001 cttatatagg ttattgatat aaagattgtt tttaaataaa cagaatcaac tttaacattc
     3061 aacagtttta gaacttcaaa aatggctaga taagaaacac atatgtaaaa agcttttttt
     3121 gagcaacata aaaattggtt taaatttcta aaattcttaa atattaaaaa tttttttaaa
     3181 gaattagaat ctaaaatatg caatttattc cctaaaatta aacttaataa atatatgcaa
     3241 aacaccatac caaaaggaaa caatgctatc attaaataat aaataaaatt tgtataccca
     3301 ttaaaataaa tccatttgct atatccttga aattctttca taaaactata acctattaat
     3361 gttgaagcat atatatcaat gaaaaccatt acaataaccc caaatactga accatatact
     3421 aaatcatcca taaccattgt aggcttattt attagatagc cacacattat accaagtaat
     3481 acactctgac ttgcccaaat agcagttcct agatttccaa gtaccagaga aattattaaa
     3541 agcgaagtaa ttccagataa aatggtatac tttaaatcac atttcaagca gattatacaa
     3601 aaaaatactg gcactataaa atctaagtaa atagcatatc caaatccagt actcacagct
     3661 ataattgtta ctactatgaa taaagatgac aataaagctg cttcagttaa ttttttagta
     3721 gtattcaaaa cactgcctcc ataaatcata aattttctaa ctaaagtttt gtttttaata
     3781 tagtatatca ctttttaaaa atatttttaa taaatataaa ttttaataaa ggtatttatg
     3841 ttaaaaatgg tataatgtat cttaatattc agttttttag gatgctagga ggtaattact
     3901 atgtttaaaa ttaaacactt taatgatttg agtttagatg aattttatga aatagcaaaa
     3961 tcaagatatg aggtatttgc ttgtgaacag aagatatttt cattaaacga ttatgatgat
     4021 atagataaaa gctcttatca catattttta aaagaaaatg gatttatttg tgcttacgct
     4081 agaataattc ctaaagaata cagctcttat aatgatgttt ccattggtag agttttagtt
     4141 ctttctagtc atagaagaaa aggattagca aaacaaatga tggattgtgc tatagatttt
     4201 ataaaagtta acttacacga aaataatata accttatcag cacaaactta tataaagaac
     4261 ctttacttat cttgtggttt taaagaaatc tcagaagtat acgacgaagc aggtattgaa
     4321 catattaaaa tgagattata gtgttgacaa gctaatattg ttaatatata atttaagtat
     4381 aaattaaata ttgaattgat atttaggtat ttgaaaatac cttacataga gtcagaaggc
     4441 ttttgctttc tgactttttt attatcaaaa ttcaataatt atatggattc aaagtgttaa
     4501 tttttattct atattctact ttccccaaaa gtaagaatta tacccaactt tgtatgatag
     4561 gcatcttgcc tatctttttt ttgtaaaagt aacaaggtaa taatataatg catagtttaa
     4621 aataagaaga ttagcccagg ctaaatttca agcatggagg tgctattatg aaaaacctta
     4681 acgatattca agtgaaaaaa actgtcaaag ttgaagatat attatctagt ggtaatttaa
     4741 gagaaagaat gttagcgctt ggtcttacta gaggagctgt tatagatgta gttagaaaag
     4801 gtccaaaaaa taatttaact gtctataaaa tcagaggtag caagatagct ctacgacaag
     4861 aagaaagtag cttaatatta gtttctgaca tttaaaaatt tctagcagga ggatattaat
     4921 atggggttga cacataactc aactaaaatg agttctttaa aagacatgtt tgatatagac
     4981 aataaggaag accagtttgt aattgcactg gctggcaatc caaatacagg taaaagtact
     5041 gtatttaatc atcttacagg gcttagacag catactggaa actggccagg aaaaactgta
     5101 gctacagctc gtggtaattt taaatataaa aataccgaat atgcattaat agatttacca
     5161 ggaacatatt ctttatttgc cttatcacaa gaagaaattg tagctcgtga ttttatatgt
     5221 tttggtaatc cagatgcagt aatagtagta tgtgatgcta catgtcttga aagaaattta
     5281 aatttagtat ttcaagtgat ggaacttaca gataaagtta ttttgtgtat taatttaata
     5341 gatgaagcta gaaaaaaagg cattactatt gataaaaaac ttttagagga ttctcttggt
     5401 attccagtta ttttaactgc tgcaagaaat ggctctggta tggatgaact attggatact
     5461 ttaaatgatg tatcttttga caaatataaa ttaaataata aacctgttag atacaatgaa
     5521 aatatagaga atgtggtaaa atcaattcaa ccagaattgg ataatattat accaggtata
     5581 aattctaggt ggttgggact tagacttatt gatggcgatg aaagtatatt tgaatctatg
     5641 agtaattata tagacaaaga ttctatagat gctattaatg aagtaaagaa aaagattcca
     5701 gacaatataa ataaacagaa aataagagat gaatttacta aaatcaacta tgattatgct
     5761 aaaaaactga gtgatgagtg ttgttctaat gttgctaaaa aatcaactga tagagaagaa
     5821 aaagtagata aaatattaac atctaaaata tttgggcttc caataatgct cttattatta
     5881 ggtactatat tgtggattac tatagaagga gctaactatc catccacttt attatctaat
     5941 ttattactcg gatttgagcc aagtatttcg ggtatattaa atagtattaa ttgtccatca
     6001 tggttaaatg atatgttggt tttaggatta tacagaacat tagcatgggt aatctctgta
     6061 atgctacctc ctatggcaat attttttcca ttatttacct tacttgagga ttttggatat
     6121 ttgccaagag ttgcatttaa cttagaccac ctatttaaaa aagcttgtgc acatggaaaa
     6181 cagtgtttga ctatgtgtat gggatttgga tgtaatgcag ctggagttat tggttgtagg
     6241 ataattgact ctccaaggga aagacttata gctatactta caaacaactt tgttccttgt
     6301 aatggtcgtt ttcctacttt gatagctata tctacaatat tttttagctc agttataacc
     6361 aactctttcg tatcaagcgt agcaactgca ctttgcataa ctttactgat aattctaggt
     6421 gttataataa cattgttggt ttcttatact ctttctaaaa cgctattaaa aggagttccg
     6481 tctacattta cattagaact tcctccttat agagttcctc aaataggaag aactttatat
     6541 acctctataa tagatagaac aatatttgtt ttaggaaggg ctgtaatggt agccatacct
     6601 gctggtgtca taacttggat atttgcaaat atatatatag gagatttaag tatattatca
     6661 catgttgcaa actttttaga ccctttagct aaattaattg gtcttgatgg ttttatatta
     6721 cttgctttta ttcttggatt cccagcaaat gagatagttg tacctatact tttaatggct
     6781 tacctagcaa ctggttctat gatagaatta gatagcttta gtgctttagg tcaagttctt
     6841 agagaacatg gatggactta tttgacagct ttaaatgtta tgctgttcag tttactgcat
     6901 tggccttgtg caacaacact tttaacaata aaaaaagaaa ctggtagttt aaaatggact
     6961 gccttaggat tcttaatgcc tactatactt gcttttgttg tttgtttttt aacaactaca
     7021 gtttacaatt tatttatata attagtatta actgacagta gacatatatt agagaaacca
     7081 tttaaaaatt tatatacttt attataaagc atagagatat attcaatgat aagtaaaatt
     7141 acttaacatt tgaatatatc tctattttaa ttcttatctg gatacttgga ttgaaatttc
     7201 agtcatataa ttatcttcat tactttcaca aaaaaagtca agtatactct cctcatacga
     7261 atttccaaca attttatatt cattttcata tatatatttt ttcaattttt cgtaagattt
     7321 atatgaatcc tcatattttc caatatgttt tatgcaagca tacattcctt ctggctttac
     7381 atatagcttt ttatccttta tttttttatc tatcttcaaa taaaaacttg atatacttaa
     7441 atagtcccca ttttttatat tttcattact tactattact cccaactcat atccttgata
     7501 caaatttttc gatttacaat aattggtaaa atctattaat tccatcataa aatcactatt
     7561 actcatatta ctcaaatcgc ttgatagaac taaatattct tcaaactttt tggatatata
     7621 aatttcttca ctattcattt tagaaattcc ttcaactgtt atatttattc tattttgcat
     7681 cttagaactt atctttctta gtttttttat tttttctctt atcttttttt cttcttcttt
     7741 aagcattttc acacaaagct ggggagttct attttgtata tactctttta tttcctctaa
     7801 actcattcct atttctctta atgattgtaa tatatcaagt gtatcatatt gataaactga
     7861 gtaatatcta taattatttt tatctttata ttcaggagaa aaaataccta ttttgtcata
     7921 gaaaattaat gtctgcttag atataccaca caatttagca aattcacctg ttgtaaaata
     7981 ctgtttttcc aagggttata cactcctttt ctttttgttg tctatatagt tactatattc
     8041 tttattattt actaaatcaa gtagttatta ttttagaaaa tcaatatgat tttgatttta
     8101 aagcttaaat atcagttaga tgtcagttat aaatatttta cccattccca tcataaaaaa
     8161 gatatcccct cttaactttt ggatggaata ttatatttat acttgttaga gtgaaaattg
     8221 taataggtgc tacaataaga tatttaatta aacataaagt taattattgt aataaaaaat
     8281 ctttagataa attagagtta aagtatggaa atatagatag agaaaaagct gttaaactag
     8341 aaatatttta tcaatattta atagaacttg aatatataga aatgagttta ttaataagaa
     8401 gattagatac tgcaataaca tcattagcat tagtatctat tataacaata gcatcatatt
     8461 atttaatcag aaaaaatgtg taattatgta agctatttat aataaaacac tgataaaatt
     8521 aataataaaa aggtaatagg atttctatac taccttttgg tttttataat atagtgtaat
     8581 tttattatat ttttgtatgc taatataact agataatcat aagataactc attaaaagaa
     8641 aattataaaa acttacattc tgtatagtta atataaaaca taagtaatat aaatttatgt
     8701 aaagcaacaa aagatggatt tacattccat atagttaata taaaacgatt tcaaatgatt
     8761 agaataaaaa tatcagaatt gctatttata ttccatatag ttaatataaa actttaaatc
     8821 atctttatga acttcaaaag taggaagcgt atttacattc catatagtta atataaaaca
     8881 aagattctag taataatagt attagttttg tttctaattt acattccata tagttaatat
     8941 aaaactcaaa ttgaaaagtt cagcagaaac aggagcaata acatttacat tccatatagt
     9001 taatataaaa cctgttccaa ctggtcttgc agtctgttct tgaccttgat ttacattcca
     9061 tatagttaat ataaaacggt ggaaaaatag ttagtatgat tggcggagtt ataatttaca
     9121 ttccatatag ttaatataaa actagaaggt ttagaaaaga gtttagaaaa ttttgcaaat
     9181 ttacattcca tatagttaat ataaaacaaa acgtcaactg ctaaaactaa gtaggtataa
     9241 ataatttaca ttccatatag ttaatataaa acaccaaaat aaacttagta ttttcaacac
     9301 ttacacgtat acaactctct taaatttgca gtgaacgagc aatagtgcaa ttgataacgc
     9361 ttatcatgca ctctcaacgc cttatatttc aactgttacg ccaaattttt tcacaaatat
     9421 cgctcactgc aaaatttcta taattttatt atatcataaa tatattactt ttgaatattg
     9481 ataccaattt ataccataat aaaagcaaaa aaacgtaatc tatctacatt agatttaaat
     9541 tctataactt aaagttttta cataatattt atgcttgttt aatcaatcta atatatcatt
     9601 cttgtatatt gcttctaata gtcttttttc ttaaataaat atctatctga acaagcatag
     9661 tttaattaaa aacttttgta ttcccttaaa actgtatcta cctcttatta ttttatttat
     9721 gatatattat ttttaatcta aaaatagata tctattttta ttatggttat ccctttttaa
     9781 aatactttaa tcatatacta ttcccaattt aacatccatt gaaatgctat tttcttatat
     9841 tacaatttat aattgatata tcttcaatat aataatttaa tgtatttttg attttaaagc
     9901 ttttcagtga tattattaat aaattagaat taattatcta gctttaaaag gtcaaagatt
     9961 tctgttgctg tctgcggttt tccaaataaa tatccttgta tgtaatctgg ctttatttgt
    10021 ttaactaaat catactcttc ttgtgtttct acaccttcta aacatacttt tattcctaca
    10081 tcgtgacaaa ttgcaacaat aaaatgtata aatgtagcat caaacttact ctttaatata
    10141 tctttaacaa atactctatc aattttcact atatctattg gagaaaattt taaaacttct
    10201 agagacgagt atcccgtacc aaaatcatcc atagcaatat aaattcctaa atcttgtaaa
    10261 gccttaaatt taaactgtaa aatactcata ttttgtactg tatgactttc tgtcaattct
    10321 aaaacaagat tttgataagg aaaattttca tcatctataa tttttactat atcttcaata
    10381 aatgtgtctt ctaatatttg aacagctgaa acgtttacac tcactttaaa aaaaggatag
    10441 taatcaatcc atttcctaaa agtacgtaat gccattcgaa gcacccaagc ccctacaata
    10501 tttatcatat cattttcttc taatattgga ataaattcca aaggagaaat tgctttgcat
    10561 ttgtcattag tccaccttaa aagaacttct acacctatta ttttatgact ttctgtatct
    10621 acttgtggct ggaatcgaag actaaacccc ctaaaatcat cattaattga tgcctttaaa
    10681 tcccgcatca tttctaatga atacatttta ttttttaata tttcttggga gaaaaaaaca
    10741 agcctgtttt taccatgctc tttcgcatat tgtaaagagt aactagcaca cttataaagt
    10801 tcttttactg tatctccatg ctttggatat attacacaac cagcagaaat tgttatattt
    10861 aatccatatt ttctccatag ttgaaggtgt ataatcatat tctgtatttg attatataga
    10921 gttagaattt cattttcttc aacattatca acaagaatgc ccatttcgtc cccatcaagt
    10981 ttataaagtt cagcattatc tggtaaaata gattgtatag actgtgctag tgtttttatt
    11041 atattatctc caaaatccct atcatacatc tcattaacat ttttaaaatc gtcaatattt
    11101 aataatacta tgcataattt ttcaatcata ggatttgaaa ttttatcttc aaatacactc
    11161 ataaattcat gataattcag taactgtgtc aatgaatcaa tcttattttg tttacctaat
    11221 tgcgtcatta ttcctgcaaa aatacttggt tctccaaatt catcacgcat tagttgacct
    11281 ctacatctta accatatata ttctccacta cgatttttag ccctaaattc cactgtatga
    11341 taatccatct ggtttttacc tatttcagtg tttgacttat aaaaacgatt ccagtcttct
    11401 ggatgtacaa tttttttcca gtaaacaagc ggattttcaa caatttctcc tggtaagtca
    11461 aataattcaa cttgtgatgg tgaatatcga aatacgcctg ttttcatatt gcaaatgtat
    11521 atatattcat ctgtacctct aatcaaagca tcgtaaagca atgtagaatt ataatcaaaa
    11581 ttgtctcttg aaaaattaaa aactcctttt tcttctttat tatttgatat ttcatgaaat
    11641 tcattaatct taattggttt atttaagctt gttgagtttg caatatctat tgattgatgc
    11701 atatgaacaa ctgtgccatc ttgccatgta attaaactat cataattttc aaaaacacga
    11761 tttaacttat tacatttttc ataccacttt attaatactc cttttttatc attctttaat
    11821 aattctaaaa ctttacaaaa actacaagta gaattttttt caggatataa tacttgccaa
    11881 caaacttttc cttctggatc taaaatatta tattcttctt tcattttttt gttcataaaa
    11941 ataatttcat tagtatgaat atttgtaaca tatatattaa tctgtagttg atttaatata
    12001 acttcaaaat tatgtttgtt catatactta tctcctccat agttactgct ctttataaca
    12061 acattgttaa aattattctt tttagaagat ttacttataa cttatacata tacactaaat
    12121 accttaattt aattagaaag tttattactt catattttaa attataattg ataaaaaaaa
    12181 atacagcaat atagtattac caatttaaaa aaaattaata ttacataata catctctctc
    12241 ttatattaaa ttttaacttg gtactaatct tgacaaattg tccacaaaaa taaattatat
    12301 attttattat tgttttaaat ttttataaaa aatcagtatt attgatacta ttgaagttaa
    12361 aaagcattaa tttctaaaaa catcataatt
//
LOCUS       DAEQAF010000106        12281 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.109, whole genome shotgun sequence.
ACCESSION   DAEQAF010000106 DAEQAF010000000
VERSION     DAEQAF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12281
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.109"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            234..416
                     /locus_tag="KRN00_003094"
     CDS             234..416
                     /locus_tag="KRN00_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828946.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            1248..2162
                     /locus_tag="KRN00_003095"
     CDS             1248..2162
                     /locus_tag="KRN00_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBH1828947.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVNPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            2552..3199
                     /locus_tag="KRN00_003096"
     CDS             2552..3199
                     /locus_tag="KRN00_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBH1828948.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNEALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(3366..3935)
                     /locus_tag="KRN00_003097"
     CDS             complement(3366..3935)
                     /locus_tag="KRN00_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828949.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKDNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(3940..4839)
                     /locus_tag="KRN00_003098"
     CDS             complement(3940..4839)
                     /locus_tag="KRN00_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1828950.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(4850..4999)
                     /locus_tag="KRN00_003099"
     CDS             complement(4850..4999)
                     /locus_tag="KRN00_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828951.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(4992..5576)
                     /locus_tag="KRN00_003100"
     CDS             complement(4992..5576)
                     /locus_tag="KRN00_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBH1828952.1"
                     /translation="MKKFFMVVLGCIFVLGVISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            5997..7322
                     /gene="cdeA"
                     /locus_tag="KRN00_003101"
     CDS             5997..7322
                     /gene="cdeA"
                     /locus_tag="KRN00_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBH1828953.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFISSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKGRYKY"
     gene            complement(7417..8211)
                     /locus_tag="KRN00_003102"
     CDS             complement(7417..8211)
                     /locus_tag="KRN00_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1828954.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(8212..9087)
                     /locus_tag="KRN00_003103"
     CDS             complement(8212..9087)
                     /locus_tag="KRN00_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828955.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSPDFKVGQIFEFSSS
                     FYKSYDKGLEEELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(9091..9459)
                     /locus_tag="KRN00_003104"
     CDS             complement(9091..9459)
                     /locus_tag="KRN00_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1828956.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(9642..10301)
                     /gene="deoC"
                     /locus_tag="KRN00_003105"
     CDS             complement(9642..10301)
                     /gene="deoC"
                     /locus_tag="KRN00_003105"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBH1828957.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(10337..11524)
                     /gene="murJ"
                     /locus_tag="KRN00_003106"
     CDS             complement(10337..11524)
                     /gene="murJ"
                     /locus_tag="KRN00_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBH1828958.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTVFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(11601..>12281)
                     /locus_tag="KRN00_003107"
     CDS             complement(11601..>12281)
                     /locus_tag="KRN00_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1828959.1"
                     /translation="RILNATISKEPSGRYYVSLCCTDVDIEVFENTNNHIGLDLGIKE
                     FCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQR
                     NDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWHG
                     RQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEGL
                     RLITIQNK"
BASE COUNT         4276 a         1894 c         1371 g         4740 t
ORIGIN      
        1 attaatttat attaaatatc tactaactca aatattcata attaaacttt aaactggata
       61 aattttcttt taagaatgaa agtttatcca gttttgcgat tataataacc agttttacat
      121 atccacttgt aaaatatatc taagcaatat atcatactat atagatttat gagtgaaata
      181 atatctgcta tttactgaat atttttattt ttcgtttttt agggggatta gttgtgttta
      241 aagataagat tgatgaatgt gttcatataa tgactgcata tattgctagt ttaaaagaat
      301 actattcatt catagaaact caaattggtg attttattaa aaaatatgga gaagatgttg
      361 tagagttatg tctccataga gtgatgattc tactatgcga atgtggtttg gcataaaatt
      421 aaatttatta aaatgggtaa gaagaatcct atataatatt cttcttaccc attttaatat
      481 atcaatttca tagcttatcg tttaaaatat tttacatcca ttactagaca actttacatt
      541 ctctttttaa ttctagtata tttaaatcat tttagttgct ccttatttat tcttattact
      601 tgttttattt tataaataaa ataattcttt ttaataatgt tttttgttga tattcctatc
      661 acacatccaa ttatttatca ttgtcttgaa attgtttgca tacttaattt aatccaattg
      721 aaacacccca gcatagaatc ccctgtaaaa tagaagttgg attaaatcct aacatctata
      781 cagaaaatac tactccaagc acaagcaata taatggaata tatttatcac ttaatttttt
      841 atacttttta aatcccatac ctaaaacatt aagtgcagct attagaatta ataattgttg
      901 tggtataaaa ttatgcttgc ttcatattta ttcatttttt gctataaaag ttcttgtttt
      961 acaaaaaaca tttgttttgt atcaaaataa tacttataaa ttacataatt ctcataaaaa
     1021 tttctagtat tacttgtact cttaataaat aatagccaac aagtacctta aatcattata
     1081 tctatatcta ataagaaaca cagtaagata attttttcgc ccataactta ataaaaactg
     1141 ttgatattag tagcaattga atttagttaa tttatttata atatacataa atttaaatat
     1201 tacgaataaa gtattataaa taggatactt tctaaaggga ggaaattatg atagataatc
     1261 aaaaatatgt tattttatca ctagaattac atttattttt ttcaagaatt atgaaagagc
     1321 atgctctttt tttagaagca ggattcacaa ataaaaatta taatcttgct atggaagctg
     1381 accattataa aaagcaattt gaagatttat tatcatacac tgttagtgct agtaatggta
     1441 taattagacc tgatatatta tattcagaag agcttgtaac tactctcaca tcagttgcag
     1501 aacaaaaaac agaagagttt acagggatag aaataaacaa aaacatcact acaagagaat
     1561 taaatctaca aagtggtgta aacccacaag ttggtcaaga cttagtgaac tatgtagctc
     1621 aacttaactc tgatgcaata agattacttg atgggcttat taattttaaa gaaagagtct
     1681 tagatggtgt actatcatgt actatattta catcaaacta ccctctactt cttgaacata
     1741 taatacatga agcaaattta tatcgttctt atgtagttga ccttgaaaat aaaatagata
     1801 ttgagtcaaa aaacgctaaa gaaatagaat tattctggga ccatattatg atggaacatg
     1861 ctctgtttat gagaggatta ctagacccct cagaaggtga actaataaat acttcaaatg
     1921 attttgctat aaaatttaat gaattaattg aaaaaacaaa cgaaatgact gattctaata
     1981 tcaagaacat tacagaagaa actctaaatg aaactgttga gtttaaagat tttaaagaag
     2041 caggagcatc aggaatagaa caatgtaaga taaaatctat aatattacca cttttagcag
     2101 accatgtttt aagagaggca aatcattata ttagaatatt ggagagttat aaaaacatgt
     2161 aattaaaaat tacttttaaa ataatctttg catatttaga taaaataaag gtacagttaa
     2221 ctgtaccttt attttttata aacttataaa atttaaacaa gttattcata aaataaaata
     2281 ataatcatct ataacccaca actttatttt atattaaata aaaagtatta gtgattatgt
     2341 tttataggta tttctttatt cagttattta ttaaaaacta atagtaaatc ttatactaat
     2401 cgcatattta tgttataact atattgtaac tattttctta atcttaggaa aagattactt
     2461 ataaaattaa ccttatacaa taatatatcg tataatctta attagcataa tagttacaat
     2521 attaaaattt aaatatggga gtgattttag tatgataaga caaacaccat tagagaaacg
     2581 atatgacaag ctaggtcctc atattgtaac agcactcaaa aaacgttatt ttgatgctta
     2641 ttactgtaaa actagaaatg aagctttgca acaaatttta gatttaattc ctcaaaatca
     2701 tgtagtatca tggggaggat ctgaaacact taaagaaatg ggcgtacaaa ctgctgttag
     2761 agagaaagga tttaaagtta ttgatagaga tttagcaaaa actccagaag aaagaactga
     2821 aattatgcgt caagcacttc tatgcgatac ttttttgatg agtagcaatg caattagtga
     2881 agatggacaa ctctttaata ttgatggaaa tggcaatcgt gtagctgcaa tgatatttgg
     2941 tccaaaaaat gttatagttg tagctggtat gaataaaatt gtaaaaaaca ttgatgatgc
     3001 aatacaaaga actagaacaa ttgcatctcc agcagttgtt cagcgttttc aagatgtcaa
     3061 tacaccatgc tatattaatg gaagttgtat agattgcaca agtcctgaaa gcatttgtgc
     3121 atacatggtt actacaagaa tcagtcgtcc agcaaaaaaa ataaaggtaa tattggtagg
     3181 agaaaatctt ggtctataaa atatacatac atgtaaatag ctctataaat aataaaatca
     3241 tatgaaataa cttatttcta aaagtggtag aataaaagct tctacaagac tttcattcta
     3301 ccacttttat attcttttaa tttgtgtttc tatattatta attgctccga ttttcatata
     3361 tattactaac tatttttatt ttcataattt ttttgttctt catcaagctg tttataataa
     3421 tctttattat agtcagctag ataatctata ccacctcctg taatcacatt taataatttc
     3481 attgcagatt cttgattaac tttacaaaca taattatcac cagatttaac aagctctaat
     3541 gtaatattaa attctttttt ctttgcagaa tcaatatctt tcatagttgg atttggcatc
     3601 atttctccta gtttaggagg attctttttt aaaatagaaa ccatatcagt attgttaatt
     3661 tttaaatcta cagtcacttt atccttatta tcctttatat ctgaaatttc ccaagtcata
     3721 tttttagaat acattttaaa tccttcttta tcttcgtata taagattacc taaccctgat
     3781 tttgggaaat acttatcaac agtatctgca tcttgtgttt ttattgaatt aaacatacta
     3841 tccacttcat tttttatctt attatcatta gtacaaccag ctaacaccag tactgatatt
     3901 gcaaacatta taatacatat aataaatttc ttcattaaat tatatccccc tatacttttt
     3961 tgcacaaata ttattctctt ttttatcttt tgaaaaagtt gtagtaattg cattttgtgg
     4021 acaaactttt atacattcac cacacctaat acagtctgga ctatttacat ctttatatat
     4081 tggtatatca agcttacatt ttgtttgaca tgctgtacaa tttgtacatt tatctttatc
     4141 aattttaaat ctatatattg aaataggatt aaaaaaacca tagattgctc ctaaagggca
     4201 tatatacttg caaaatggcc tataagtaat gattgacatc aataatatca atagcaaaat
     4261 acttaacttc cagctaaata aaaatcctat tgattctctt aaattctcat ttcctaaaat
     4321 aagtggtatt cctcccaaaa gtgttcctga agggcaaatc catttacaaa accaaggatt
     4381 tccaccccct gctacattta caatagcaac tggcaaaata attacaaaca ttattaagac
     4441 tatatacttt agatatttta gatatttatc accataaact ttttttatct ttactggaaa
     4501 gggtacttta tgtagtaaat cttgtacaag tccaaaggga caaagccaac cacaaacaaa
     4561 tctgccaaaa aaagcaccaa atgccattaa aaaaccaaca acataaaatg agaatttata
     4621 ctctctgctt gataaaactg cttgtaatga acctattgga catgctccaa gtgcacctgg
     4681 acatgaataa caattcaatc caggtacaca taatttttta ctttctcctc catatatagt
     4741 tccttctaaa aatccattta catatccatt tgttaatgct gtaaatgcaa cttgagtaat
     4801 aagtcttata ttattattta ccttagataa taacttcatc cctcttctcc taaccaatac
     4861 caatacactc aagacaaatc ataattgctt tagttaatac tgtatttgtt tctccacgat
     4921 atgtacctaa tgcaataaat ataatactaa ttgcaataat agaaatgcct tttttattat
     4981 ctttaataaa attactcatt ggcttttacc atttttagtc tttcatctat aatttttttc
     5041 caatcttcct tactatttgc acctacaacc ttctcaccca caaagtttcc tttcttgtct
     5101 acaaaataag ttgttggaaa ctccataact cttttaaaat cagttttttt aagttcttca
     5161 gatacagtca attgttggta agttgcatct gactttttca taatgtcttt aactaaattt
     5221 ttctcttcat ttgaaagacc agttctcata tcagttttat caacttctac aactaatccc
     5281 tttatagcta cattggaatt attactctca tattcttttg ataatgcttc aagctctggc
     5341 atttcaccca cacatggtcc acaccaagta gtccagacat taataagagt aagttcttta
     5401 tttgaaaata tctcttttgt taccttattt ccatcaacat cctccgtatc taaattacta
     5461 aaccattcac tattattctt gtttttttct actggcttag attctttttt gctacatcca
     5521 gaaatcacac ctaaaacaaa aatacaccct aaaactacca taaaaaactt tttcatatct
     5581 cacactccta aaatttatat agtatataaa atcgctgttt gaaataaaga taacttctct
     5641 tctatattaa aacattatat ttaataaata agaactattt aaaataagtt gtataaaaga
     5701 tatacagtta aaatctattt cttttcagac aaaatcttat atatatataa taacttataa
     5761 aacttaagat tatatacata tatttctaaa aattttctta agaaacagtt ataccttact
     5821 aatgcaatat acctattttt actaatataa gtttattaat tagcactata ctaatttatc
     5881 ttaatatgat tttttgttga ttttaagctg tttatcgtat aaataaaatt tttcttgact
     5941 atatagttac tatatagctt attatatata gagagtaata aaaggaggta aaatttatgg
     6001 aaaatttatt tacaagaaaa ttcactactt ttgaatttct aaaatttgtt tctcctgcaa
     6061 ttatatccat gatatttata tctttgtaca caataataga tggcatcttt gtatcgacat
     6121 tagttggttc tgatgctctt gctagtataa atattgtact acctataatt aaccttgttt
     6181 gtggatttgg aataatgatg gcaactggtg gaggtgctat cgtttctata cgtatgggtg
     6241 aaaatagaca ggatgaagcc aactctacat tttcttttat agttttgttt tcattgattg
     6301 ttgggatttt attcacagta atctcatatt tctttatcaa agaaatatct attttgcttg
     6361 gtgcaacaga taagttatta ccatattgca taacttatgg taaagttatg attttatgta
     6421 caccatttta tattttaaaa tttatatttg agtactttgc aagaactgat ggaaattcta
     6481 aatttagttt atttctatca gtcattggtg gtgtaacaaa tataatattg gattatgtat
     6541 ttattaaata ttttggaatg ggtcttttag gagctgcagt tgcaactgct ataggtatta
     6601 ttttaacttg tgttttaggt attatttact tcttatctaa taaatctaca ctaaaattaa
     6661 gaaaaccaaa aaccgatttt agacttataa gagatactat gataaacggt tcttctgaaa
     6721 tggttacaga attatctaca ggaattacaa cattcttatt taatgtagta gctttaaaat
     6781 tagcaggaga aaatggactt gctgctctta ctatagtatt gtatgctcat tttttaatga
     6841 catcagtcta tctaggattc gctgctggag tgtctccatt aataagctat aattttggtg
     6901 ctgaaaacag tgataaatta aaagaaacat ttaaacattc tctaaaattt atatttattt
     6961 cttctctttt agtgtttatt attgctttag tatttgcacc atttattgtt agggtctttg
     7021 taagtccaga taacacagta tttaaactag ccttacaagg attaaaaata tttgcatttg
     7081 cttttttgtt tgttggtata aatatatttg catcaggatt ttttacagca tttcacaatg
     7141 gaaaaatttc agctattata tcttttagtc gtgcctttgt ttttataatc ataggaatca
     7201 taattcttcc tcctatgtta aacatgactg gattatggct tacagttcca tttgctgagg
     7261 ttataaccat atttatatct attctattta taaaaaaata taaaggtaga tataagtatt
     7321 aaaaattaat acttaaaatc aacatttatt aaaactaata aacctgcttt aaaatacaaa
     7381 tttacaaatt tgatttttaa gcaggtttta ttttagttat aataagtcat ttgcatactc
     7441 tttaattggt gcttttctaa gtaataaaat tataaatatt atgcaaataa ctataattcc
     7501 tacctttgtt ccaaataaaa taaaaggatt ctgaaatgaa taaataattt tttctaaata
     7561 cagtagcatt ttatgcatat ttttagttgc aaaattaact atataaatta ccattaatat
     7621 cggtaatcct atcaatatag taatactagt aacttttcta actctatatg taaaagctcc
     7681 aagtaatact cctataaaac ctatacatat ttcatttata catatttgta caaaataatt
     7741 taaataagtt agtggcatac ttgatgttga aggatctatc agtgctgata tagatgtcca
     7801 aatcatatct ctctttagta aaactgatag ttctatactg taacctgtta taatttctat
     7861 aaataacttc gataaaaaaa tcaaaactat acctaaaata gaaatcacaa agcttaaaat
     7921 aattaaatct atgacaatag cttttataca actttttcta tctgctctta tacttaaagc
     7981 tcctgaaaag tctttatttg ctatatttac tccatacaca aatagcagta tagttatata
     8041 tgttaaaata ggattcacaa tcgtggataa attagtttta gatgcttctc caaaaatctt
     8101 gagaataaac actggcaaaa tattcataac aattcccaca atcataaata taattatata
     8161 taatttagta tttttattaa aaaattttat atatggcttt aattcattca attacaattc
     8221 ctccttctta gtcatgttaa caaacatatc ttgtagccct atgtatccta catcaatatt
     8281 tgaattttta agtatttttt catcattttc actaaaatca ccatagtaaa aataagcgac
     8341 tgcatttcca aatgcctttt taggttttat attttttata cattctaatt tttctaactc
     8401 ttctttattt ccagtaatat aatgagcttt ttgttttatg acatcaattt cttcatctat
     8461 aataattttt ccctcattta atattattac atgctccagt aaatcatcta tttcatcaat
     8521 caaatgagtt gatattatta ttgtccttgg attttttata taactatcta aaattatgtt
     8581 ataaaactct tgtctattta ctgcatccaa accaattgtt ggctcatcaa atatggtgat
     8641 agctgaatta gaacaaatac ctattatatt tgaaagtata gttttcatac ctcttgacag
     8701 ttgtttatac ttttttttag tatttaaatc aaaatatttg cataattctt cttctaagcc
     8761 tttatcataa cttttataaa aactagaaga aaattcaaat atctgaccta ctttaaaatc
     8821 tggactataa aattcttttt ccctgacgat acaaacttct tccaaaactt ttatatcttc
     8881 ttttgggttc tttcctaata tttctatctc accttcattt tgaattaact gatttaccat
     8941 tatatttaat aatgttgttt ttccagctcc attcttacct aataaaccat atatcttatt
     9001 tttttcaaag tttagagaca tattattaaa aatattttgc ttcttaaaac tgtgagataa
     9061 attttctatc ttaatagaac tactcatata ttaatcctcc ttgaaattaa ttataatatc
     9121 aaccaattct tctctattta tttctaattt gttagcttct tgaagtaggt tttttacaaa
     9181 attatgttta aaattttctt ttctagcttc ttttataata gtttttgcac catctgatac
     9241 aaacatccct atccccctct tcttatataa aatattttta tcaaccaata tatttatacc
     9301 ttttaatact gtagctggat taattttata aagctttgaa agctctgttg ttgatggaac
     9361 ctgttcttct tcttttattc catttgatag tatctcatct tcaattgctc gtgctatctg
     9421 aataaatata ggttcttcat tatttaatac taatttcata ggttcctcct ttctccatta
     9481 gttagttact caactaatta accatataac ttataatatc ttgaaaaata ttttctgtca
     9541 atactaaata aaaaacagag ggaaaattcc ctctgttttt tgttctttat atttataatt
     9601 aaattttgat ttttgtaatc ctatcccata agttaaaaac tttaataatc tgttgtatct
     9661 tcatttttta atattttaca tattgagcta gttcctaacc tttctgctcc tgcctctata
     9721 aatttttctg catcagaaat tgatttaact ccccctgcag cttttatttt tacatttttt
     9781 ccaacatgct ctttcataag ctttatatct tctaaagtag ctccacctgt tcccattcca
     9841 gtagatgttt ttataaaatc tgaacctgac attgttacta tttcacacat ttttattttt
     9901 tcatcttcat ctaaataaca tgtctctata atgactttta atactttatc tcctatagct
     9961 ttttttattt cttttatttc ttttcctata ttatcataat ctttattttt tatatctgaa
    10021 atgtttacaa ccatatcaac ttcatctgct ccattttcaa tagcatcttt tgcttcaaat
    10081 acttttgtag cagtagtttg atatcccaaa gggaacccta tcactgtaca tatctttatt
    10141 ttacctttta gatattctga tgctcttttc acatatgatg gtggtatgca aactgatgct
    10201 acactcatat ctacagcttc atcacataaa attttaatat cttcccatgt agttgtagct
    10261 tttaaaatag tatggtctac tgtttttaat atatgtttca taaaatcctc ctaaatttat
    10321 aattaatata attagattac ttttttaaat gcaattttct ctttgcaatg tttagtatca
    10381 tatcaacctc ttcaacttta aaaataatca ttagtagtgt ataaattcca cctccaacta
    10441 taactgaaat agctagtgat acaaactcat taaatgttcc tactcccaaa attccaaata
    10501 taaatttata cgtaaagtat gataaaacac ccataattaa agatgcaact accgatttca
    10561 aagttgcttt tattatttta tcttgtccaa aatatccaac ttttctcttt aggttcaaga
    10621 agagtaacaa tatacatgca attgatgatg aactagttgc aagagcaaga ccaccatgag
    10681 ccattggttt tattaaaact aagtccaata ctatatttac ccctacagat ataatcccat
    10741 ttaccatagg tgtttttgtg tcttgtaatg aataaaaaac ctttcccaaa atatctctta
    10801 agccaaatgc agtcatacca actgcataaa aaattaaggc agttgctgtc atttgggttg
    10861 ccctcgcatc aaaagcacct ctctcaaaaa tgattctaac aacaggagtt gcaaaaaaaa
    10921 tagaagcaac tgaaatagga atcatagaaa ttattatcat atttatacta gatttaactg
    10981 aactagtaaa cttcttttga ttattttctg cacttaactt agataacata ggatacataa
    11041 cagatactat tgaagctgta aatgtccctg taacaaaacc atttaatcta tctgcataag
    11101 taagtgctgg aatgcttcct ttaactaatg ttgaggctaa agttgtatct accaatgagt
    11161 tcacttgatt aacagcaaca cctataaata ctggtgaaag taatgctagt aatttaataa
    11221 ggctatcatc tttaaagttt aagtagtata agtatttgta gttcgttttt ttaacaaaaa
    11281 acatgtaaaa gagcagttga actaccatag caaccacagc accaattgga agtatgtatg
    11341 gtccaaatac ggtacttaac attattgaaa taattattac tatattatag ggtatacttc
    11401 caaatccaac tacaataaag ttctctttaa tttgtaaaaa tgctgacata acacttgtaa
    11461 tacctatgaa tattattcct gttctgaacc tcccatgact aaagtcacag ggttcctgct
    11521 tcatagaatt ttgcatacta aaatatgtct tactaattct ccacaggcta tccccgtagt
    11581 tcctacggtt cttacataag ttatttattt tgaattgtta ttagtcttaa tccttctttt
    11641 aatatattta tacttgcatt tatatctcta tcgtgagttt cattacaact aggacaaatc
    11701 cattctctta tatttaagtc cttcacttcc tcgtttttat acccacattt attgcatatt
    11761 tgtgaacttg caaagaattt acctaccttt acaatttgtc taccatgcca attagccttg
    11821 tattctaatt gacgaataaa ctctgaccat gatacatcag aaattaagcg agatagttta
    11881 cgatttctaa tcatattctt tacttgtaaa tcttctatgc aaataatatc gttctctttt
    11941 attaatttag tagatagttt ttgtagaaaa tcatttcttt gattagctat atgttcttga
    12001 agtcttgcaa cttttaatct tgctttattt ctatttaaac taccgattgt ttttctcgat
    12061 aattctcttt gtaatttagc aagtttgttt aatgacttct taagatactt aggattttct
    12121 ataaattctc cacaacttga gatacaaaat tctttaattc ctaaatctaa acctatatga
    12181 ttattagtat tttcaaatac ttcaatatct acatcagtac agcataatga tacataatat
    12241 ctaccacttg gttctttaga tatagtagca ttaagtattc t
//
LOCUS       DAEQAF010000107        11647 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.110, whole genome shotgun sequence.
ACCESSION   DAEQAF010000107 DAEQAF010000000
VERSION     DAEQAF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11647
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.110"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            16..2193
                     /locus_tag="KRN00_003108"
     CDS             16..2193
                     /locus_tag="KRN00_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1828960.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYRQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            2207..2629
                     /locus_tag="KRN00_003109"
     CDS             2207..2629
                     /locus_tag="KRN00_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1828961.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            2803..3378
                     /locus_tag="KRN00_003110"
     CDS             2803..3378
                     /locus_tag="KRN00_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1828962.1"
                     /translation="MVKVLAFMGSPRKKGNVDTILDEIIKGVNDNNVEVKKYYLNDMN
                     IKGCQGCLYCRKVPTCAFKDDMIDIYEDIKSAEYIIIGSPVYICQVSAQTKLLLDRLY
                     PLTEINKSKHIPRFGQKKLIMVYTQAAPISFLFKKYFKYTAKHLKGMGLNHYKTIVVT
                     KAFERNSTKKNFKVLKKAYKLGMKIAIDING"
     gene            complement(3503..4219)
                     /locus_tag="KRN00_003111"
     CDS             complement(3503..4219)
                     /locus_tag="KRN00_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1828963.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFQNKLDI"
     gene            4384..5109
                     /locus_tag="KRN00_003112"
     CDS             4384..5109
                     /locus_tag="KRN00_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1828964.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            5169..6761
                     /gene="hcp"
                     /locus_tag="KRN00_003113"
                     /gene_synonym="priS"
     CDS             5169..6761
                     /gene="hcp"
                     /locus_tag="KRN00_003113"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBH1828965.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            7132..8037
                     /locus_tag="KRN00_003114"
     CDS             7132..8037
                     /locus_tag="KRN00_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBH1828966.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKDVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            8161..9114
                     /gene="msrA"
                     /locus_tag="KRN00_003115"
     CDS             8161..9114
                     /gene="msrA"
                     /locus_tag="KRN00_003115"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBH1828967.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNSHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            9267..10397
                     /locus_tag="KRN00_003116"
     CDS             9267..10397
                     /locus_tag="KRN00_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1828968.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNMENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(10514..11482)
                     /locus_tag="KRN00_003117"
     CDS             complement(10514..11482)
                     /locus_tag="KRN00_003117"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBH1828969.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
BASE COUNT         4531 a         1322 c         2013 g         3781 t
ORIGIN      
        1 atttgaataa aaagaatgta taataagtat aataatttgt atttattatt gggaaaggaa
       61 aatgttaata tggatagtta tagacaactt aaagctaaaa taccctgtaa ggaaacaggt
      121 atagaaataa agaggacttt atgtgatatt tgttctccag gagtacattg tggaattgat
      181 gcatatgtta aagatggtaa agtaataaaa atagaaggta caaaagaaca tccaatgaat
      241 aaagggttgt tatgtaccaa aggtctttgc aatagagaat atatctatag agaagataga
      301 ataaaaacac ctctaaaaag aattggaaaa agaggtgaag gaaaatttaa accaatatca
      361 tgggatgaag cttatagaga aatagcagaa aaattaaata gagtaaaatc tgagtatgga
      421 gcaaagcatg tagctttttt tacgggttat ggaaagtggt atagaccttt tttacaaagg
      481 tttgcatctt catttggttc acctaattat ggtacagaat ctagttcatg ttcaacatca
      541 gcacagatgg ctggaaatgt tgctactgga agaaacttta caatgcaaga tatggagaat
      601 gcaaaaactt atttagggtg gggatttaat ccatactact ctaaattttt aaatagtgtg
      661 aatctaataa aattaaaaga aaaaggtcta aaatttataa ttgtagaccc tagaataaca
      721 ccgacaactc aaaaactagc agatttacat ttaagaatta aacctggaac tgatggagct
      781 ttagctcttg gaatggcgaa tctatttata caaaaggatt taatagatag agaatacata
      841 gaaaagcatg tacatggatt taatgaatat aaagaatatg taaaattatt tgatttagat
      901 actgtaagta gaattacagg agtttctaaa gataatatag taaaagctgt tgagatgttg
      961 tcacaaggtc cattttgtat aaatgaaagt gcagctccaa tagttcacca tcaaaatgga
     1021 tttcaaaatt atagagcaat gatgtcttta tccgctataa caggtaatta tgatagaata
     1081 ggtggaaaca taccaaaaca agattacttt gctggtaaga taggtggatt ccaaacacta
     1141 gaaaaagagt ttgtaaaaga agttctacct aaaaatataa atgaaagaat tggtggagaa
     1201 agatttcctc tatggaatga aatggtgact caatttcaag ctatggattt acctaggcaa
     1261 atagaagaaa agacaccata tgaaataaga gctttgtttt gtcatgggat aaatgctaga
     1321 atgtttccta attcagggag actttttaaa gcgttgaata gtgtagattt ttttgtgaat
     1381 atagatttat ttatgacaga tacatcaaaa tatgcagata tacttttacc tgcatgtaca
     1441 tcatttgaga gagaagaatg taagagttat ccaggagggt atattacata taccaaaaaa
     1501 gttattgata aattatacga ttcaaaatca gatgtagaaa tactttcaga tttagcaaat
     1561 gctatgaata tagatgatga tttattaaaa gcaggttatg aagcaagtgt aagacatatg
     1621 tttaaaaata catgtgtaga tgtagataaa cttaaagaaa gtgatttacc attaaaatgt
     1681 aaagatttta agccatatat agtaggttca tatacaagag aagggtatga tactagcact
     1741 tctaggtttg aattaaaatc tacaattatt gaaaaatata aagattttgg gctggatgca
     1801 ctaccaacat atagaggatt taatgataat atagatgatg aatatactca tttattgaca
     1861 tcaggagcaa gaatttcaaa tgcactacat tcaagacttc atgacatcaa actttcaaga
     1921 atattaaaaa atgaagctag ttgtgatatt tctagcttag atgcaaaaga attgggtgtt
     1981 atcagtggag attatataaa aataactact aagataggaa gtttggatgt aaaagtcaat
     2041 gttactgata gagtcttata taagaatata catatgtatc atggatatag agaagctgat
     2101 ataaatagta ttatttgtga taattttgac ccttatagtg gattccctgc gtatagaagt
     2161 tgtaagtgta agattgaaaa aatgaataga taaatggaga gatataatga aaagtttatt
     2221 taaatttaat aaagaattat gtacagcatg tggagcatgt ttgcttgcat gtatagacca
     2281 aaatgataat aatatagaca atggtgaact ttttagacat gtatttacaa tagaggaagg
     2341 tgaaaatata gaatattttt cattagcatg tatacattgt aatgagccaa aatgtttagg
     2401 tgtatgtcct aaaaattgtt ttaaaaaaga agaaggattc gttgtattag acaatcaaaa
     2461 ctgtataggg tgtaaacttt gtgaaaaagc ttgtgaatat ggagccttaa tttatggaaa
     2521 tgatggtaag gcaaataagt gtaatggttg tattgagaga tataagtgtg gtatggattc
     2581 accttgtgta atggtatgtc ctacaggagc attaaaattt aataaataat tgtattaaat
     2641 tgctatacta cttttaaata attgtgttaa gaattatttt ttgctatact tttgtaatat
     2701 aaaatgtaaa taaaacaaat acaaagtata taaaatatat ttttagaata aagtgtgctt
     2761 tagattaaat ttagaaaaat aaattagaca ggagaactta atatggtaaa agtattagcc
     2821 tttatgggca gtccaagaaa aaaagggaat gtagacacaa tacttgatga gataataaaa
     2881 ggtgtaaatg ataataatgt tgaagttaaa aaatattatc taaatgatat gaatattaaa
     2941 ggatgtcaag gctgtctata ctgtagaaaa gttcctactt gtgcatttaa agacgatatg
     3001 attgacatat atgaagatat aaaaagtgct gaatatataa taattggttc gccagtatat
     3061 atatgtcagg tatcagctca aacaaagcta cttttagata gattgtatcc tttaacagag
     3121 ataaataagt ctaaacatat acctaggttt ggtcaaaaaa agttaatcat ggtctatact
     3181 caagcagctc ctatttcgtt tttatttaaa aaatatttta agtatactgc aaaacattta
     3241 aagggcatgg gattaaatca ctacaaaact atagttgtaa ccaaagcatt tgaaagaaat
     3301 tccactaaaa aaaattttaa ggtattgaaa aaagcctata aacttggaat gaaaatagcc
     3361 attgatatca atggatagat aaaagtttaa tttatagtat agctaaagga gcattaatta
     3421 ttaatactcc ttttttgtat aaaggtttct agaaaataac taataaaaaa caatattatt
     3481 tgaatacaga tattatacaa gcctagatat ctaacttgtt ttgaaaataa aagatttcaa
     3541 atttattttt gttaaaagat aacaagcctt catctcgcat cttgccaagc tctcttgaca
     3601 tagaacttct gtcaacacat aaaaaatcag ccatttcatt tcttgaaaag ggaattgtaa
     3661 actggtggct acctgtttgt tctatctgtt ttgaaaaata cataagcaat ttctcgcgag
     3721 ttgttttacg agaaagtaat tctattttat tgtgaagtaa aatgtttttt tcagctatta
     3781 attgtagcat attttcaaca agcctattat gaaatacaca tgcagatgaa caaataccag
     3841 ttacactttt aaactttata aataaaactt cgcaagaaga tgttgtggtt actgtaacat
     3901 tacttttatg tagtctagta catgcgaata cctctccaaa taaatctcca ggcaagagtt
     3961 cagctacaat attcctattc ccttcgatat cttcctttat tatatgagca cttcctttaa
     4021 gcataattcc aatagaagta acttcacttc caacagagaa tattatacta tcttttgggt
     4081 aagttttatc tacaacacct aaacattcca acatttcttc aagttcatca cttttaattc
     4141 cttcaaatag aggaattttt ttaagtaggt ctatatgctt ttctaaaaat tttttcaaat
     4201 aatcacttcc ttgttgcata tgcaaccgat aatttgtttt cattgtacta tactaagttt
     4261 ataaaagcaa ggggatataa aaatcctact acaagaaatt tgaaataaag aaatataggt
     4321 attaaaaata aatatataag aaatcaatac tttaaattaa aaaaatttta tgaggtgata
     4381 taaatgatga gaaaaataat taaaattgat gaggaaaagt gtaatggttg tggactatgt
     4441 gttgaagctt gtcatgaaga agctatagga atggtaaatg gaaaagcaaa acttttaaga
     4501 gatgactatt gtgatgggct gggagattgt ctgccaactt gtccaacaaa tgcgatttca
     4561 tttgagtata gagaagcagc agaatatgat gaagctgcag taaaagcaaa tatggaagca
     4621 aagaaagcac aaaagaaaac tttagcatgt ggatgtccag gttctcagtc taagtcaata
     4681 aatagagagg tttcaaatag tacgtctata agcaatgata tagtagagat aaaaggttct
     4741 caacttaatc aatggccagt acaaataaaa ttagtaccaa ctaatgcatc atatttaaag
     4801 aatgcaagtc ttttaatagc agcagactgt acagcgtatg catatggaaa ttttcataat
     4861 aaatttatga aaaataaggt tacattaatc ggatgcccta aacttgatga agttgactat
     4921 gctgaaaaac ttacagagat tttaaaagaa aatgatatta aaaatatagt agtaacacgt
     4981 atggaagttc cttgctgtgg tggtatagta aatgctgtta agacagctct acaaaatagt
     5041 ggaaaaatga taccatggca aatagttact atatctgtag atggaaaaat tgtagatgga
     5101 gaaatttaat taagtgaatt atagaaaaat ataataaatt ttaataaata aaaagggagg
     5161 aataaaaaat ggaaaaaatg ttttgttttc aatgtgaaca aacagcagga ggtaaaggtt
     5221 gtactataaa tggtgtctgt ggtaaaaagg ggggtacagc taacttacaa gacgaactta
     5281 caggagtgtt gattggtctt tcaagagcaa ctattggaaa taagaataga ccaacaagtg
     5341 aaacagataa aattatgata gaggggctat tcactactat aacgaatgta agttttgatg
     5401 atgaagctat aaaaagacaa attgaaaaaa ctgaggtaga aaaaagtaaa cttgtaccta
     5461 gatgttcaga ttgttcaaca acttgtaata gaaatgataa ctatgatatg aaggatttat
     5521 ggaatgataa tgaggacata cgttcattaa aatcattaat cttatttgga ttaagaggta
     5581 tggctgccta tgcatatcat gcaatggtac ttggttatac agacaaagac gtaaatgaat
     5641 ttttctatga aggattaata gcagttggag gagacttgtc tattgacgaa cttttaggtc
     5701 tagttatgaa aactggagaa ataaacttaa aatgtatgga attgcttgat agagcaaata
     5761 ctgaaactta tggaacacca gaaccgactc aggtatctat gaaaatcgag aaagggccat
     5821 ttattgtagt tacaggacat gacctttatg atttacacaa attattagaa caaacgaaag
     5881 ataagggtat aaatatatat actcatggtg agttattacc agcacatgca tatccaaaac
     5941 taaaagaata taaacatcta aaaggtaatt ttggtacagc atggcaaaac cagcaaaaag
     6001 aatttgataa tattcctgct ccaatattat ttacaacaaa ctgtttaatg cctgttaaag
     6061 atagttatag agatagagta tttactacag aagtagttgc ttatccaggt atggttcata
     6121 ttgatgaaga taaagatttt tctagtgtaa tagaaaaagc tcttgaactt ggaggatata
     6181 gagaagatgt tcatatgact ggtattaatg gaggagatac attaactact ggttttgcaa
     6241 gaggtacagt ttcatctgta caagataaag tagtagatgc tgtaaagagt ggagctataa
     6301 gacacttttt attggttgga ggttgtgatg gtgcaaaacc tggaagaaat tattacactg
     6361 aatttgtaaa acaagctcct aaagacactg ttatattgac acttgcatgt ggaaaatata
     6421 gatttaatga tttagacctt ggggatatag gtggcttacc tcgtttaatg gatatgggac
     6481 aatgtaatga tgcttatagt gcaattaaag tggcagtttc attggcaaat gcttttgaat
     6541 gtggagtaaa tgatttgcct cttagcatgg tactgtcatg gtatgagcag aaagctgttt
     6601 gtatacttct tacactactt catttaggta tcaaaaatat ctatatagga ccttctttac
     6661 cagcattctt atctaagaat gtattagata tattggttga taaatttgca ttgacaccta
     6721 tatctactcc tgaagaagat atgaagaaga ttttaggata aataaatata tctacactta
     6781 aagatattta tagttaaaat atttttaagt atgccacaat taagataagg ggttaaactt
     6841 aaaatttgat taaaaaatca attttgagat gaccctttat ttattttttg taataattga
     6901 aaaataaacc tgctttcagt atattctttt aagaattttt gtattaaatt tataatactt
     6961 agatatataa tatcttatat attttatttt aagtattaaa ggtttgaatg taacttaaat
     7021 attaaaagag gaacattgta atatgtaact tgcataaaat atatatacta tagtgaaatt
     7081 attttgatta aaatttaaaa tataaggtgt tttatgtggg ggtatatgta tatgaaaaat
     7141 tctaatttta atatattggc atttgatggt ggtggattaa aaggggcatt gagtatatcc
     7201 atacttgaga ggatagtaaa agagtatcca aatctattaa acaatataaa tatgtttgga
     7261 ggtacatcta cagggagtct aattgcacta gggcttgcgt atggtgtaag ccctaaagag
     7321 ataaaagaac tttactcaat tgaaaattca aagtatattt ttaataaaag ttatgcagaa
     7381 atactcagac caaagtatga aaacaaaaac ttaaaagaag ttttattaag tatatttcca
     7441 gaggaactag aattaaaaga tttaaataaa ttagtaatga taccaagttt ttatatagga
     7501 aatgaggaaa atgcatggaa accagtgttt tataacaata tgccaaattc ttttacaaag
     7561 actagcaaag ttgtagatgt agcaatggca agtagtgctg ctccggtatt ttttccaaca
     7621 tataatcgtc atgttgatgg aggaataata gcaactgacc cgagtttagc gtgtataatt
     7681 catgccattg acagtggatt taaacttaag aatacaagac ttttttcaat agggactgga
     7741 tatgtatata acagtataaa ggcagatact actgaatggg gagctattga ctggataatt
     7801 aataaagaac ccgatttacc aattatatct attaccttag aaggaaattc tcaaatgagt
     7861 cagttatttt ctcaaaaact tcttggagat aattactata gattaaatcc taagatggaa
     7921 aaagatgtag ctatggatga ttgtgatgca ttagaatatc taatgtcttt aggagaaaat
     7981 tgtgatataa aagatgcttt tggatggata aagaaaaaga gcttttatag aaattagatt
     8041 caatttgcaa ttgtattttt acacatgatt tcattgagta ggtaaaaata ataaaatgca
     8101 gattattaag ttacttctta gggaataaat aaagtataat ttatttaagg agtgatgaaa
     8161 atgataaaac ttgctacttt tgcaggtgga tgtttttggt gtatggtaaa accttttgat
     8221 aagtatgatg gagttattaa agtagtttct ggatatacag gtggtcatgt tgaaaaccct
     8281 acatatcaag aggtatgttc aggaactact ggtcatttag aagcaattca aataacatat
     8341 gatgatgata taataagtta tgatgaactt ctaaatatct tctggaaaca gattaatcct
     8401 acagatgatg gtggacaatt tggtgatagg ggaactcaat ataagactgc tatattttat
     8461 catgatgaag aacaaaaaaa tatagcttta gagtcaagag aacatctgga aaatagtaaa
     8521 atatttgata gtaaaatagt gactgatata attccagcaa ctaaattcta cgaagcagaa
     8581 gaaaatcatc aggattatta taaaaaaaga ccattaaact acaatatgta ttataaaggg
     8641 tctggaagat ataattttgt aaaaagtcat tgggatggaa acaatataaa tagggaagag
     8701 ttaaaaaaga ctttaactcc tatacaattt gaagtcactc aaaatgatat gacagaagta
     8761 ccttttgaaa atgaatatta tgataataac aaagagggaa tttatgttga tattgtaagt
     8821 ggagaagtgt tattttcttc aaaagataaa tttgattctg gatgtgggtg gccaagtttt
     8881 tcaaagccag ttatagataa atctatcatt gagagaagtg atttctcaca aggtatgtac
     8941 agagttgaag taagaagtgc taaaggaaat tctcatttag gccatgtatt tgatgatggt
     9001 ccaaaagaac ttggaggttt aagatattgt ataaattctg cttctcttaa atttataccg
     9061 agagaaaata tggaagcttt aggatatgga gaatatttaa aactttttga gtaattagga
     9121 atatttatta taaacttatc taaaaggtga aaatctaaaa aaatattttc accttttgtt
     9181 tttttgtcaa tagtatgata aattattaat tgtaatctta tttataccaa tagattaaga
     9241 atttaatttt gaaagagaga aaacaaatga atttaaaaga ctttaatgga aagagattaa
     9301 aatcagctag aatttttaga gcaaagacga tagaacagtt gtctaaagaa actaaaataa
     9361 ataaaaaaga tttaaaagct tttgaggaaa ataagtatgt accaaatatg gaaaatacat
     9421 taaaattatc taatatatta aattttccaa aagagtattt ttataaaaat gaaaatataa
     9481 atatcgttgt agaggatagc cactttaacc ctcaatctaa actacctaga gtagaagaga
     9541 tttcttatag agaaaaaata attataatac ataaaatata ttcatttatg gagaattata
     9601 ttaagtttcc aaaagaaaac ttgccaaata gaaaagtaat gtcagatatt aatataaatg
     9661 atatagaatc tcttgcatat aagactagag agttttggga tttaaatagt actccaatag
     9721 taaatatggt aagtttgtta gagtctaaag ggattataat atcaggtatg aatgtagata
     9781 gaaaaggggc aactatcttt actcaaaaac agagaattag taaagaatct aaatatctaa
     9841 tatctctggg taatgacaaa aagtcagcat caattagaaa ttatactttg gcatgtgagc
     9901 ttggatatat aatatcaagt gaattaagaa taccaagtaa gcaattttca gaagatgagt
     9961 atgcctgtgc atttttattg ccaaaagaga gttttttaaa agatttgact catccagaag
    10021 atttagatta ttatgtagaa ctaaagaaaa aatggattgt acctatatct gctatgattt
    10081 ttagagcata taatctagaa aagataaatt acaaaaaata caattatctt atgaatgaaa
    10141 tggataaaaa aggctggttg atagaagaac cactagacaa aatgaaaggt tcaagcccaa
    10201 cgtatttaaa aagagcagtt gaattattga tagaaaataa aataatgagt gtaaatagta
    10261 tagtatcaag tttagaggaa tttggaataa atctttatcc agaagactta gaattattga
    10321 tgggattgaa aaaaggattg ttatctcaag aggtaaataa aaaaagtaaa gttataaaat
    10381 ttgatggtaa aaaataggtt tatattttag tattaaaatt aaaagcaggt acaaatgatt
    10441 taaacattaa cttagttaaa agtcttttca ataagtcatt tacctgcttt tagtgtaaga
    10501 aagaatattg aatctaaagt gtttttgaaa gtgcaatata ttcccttaaa acagaacaag
    10561 atttattaaa ttcgttttgc tcatattcag tcatattgat ttcaataatt tcttcaatac
    10621 catcttttcc tataacacat ggaacacctg caaatacatt tctttcgtta tattgacctt
    10681 ctagtaatgt agaaactgga agaacttttt tctcattgtg tagtatagct tttacaattt
    10741 ctactaaagc agtacctata ccaaattctg tacaatcttt accatttatt atacttatcc
    10801 ctgttttttt atttttttca actattgatg gtaagtctaa attgctataa gtacttgggt
    10861 tgtcttttat catgtctaag attggtttac caccaattga aacatgagac caaggaacca
    10921 tttgagaatc tccatgttca cccatagaat aagcttgaat tgattgttga gcgattccag
    10981 tttcttcaga taaaatcctt ctaagtcttg ttgaatctaa agctgttcca gttccaatga
    11041 ctttgttttt aggaaagcca gatttttccc aaatataatt tgtaactaca tcaacaggat
    11101 tagatatgac tacaaatata ccatcaaagc cagaatcaac tatgggtttt actatagatt
    11161 ttatcattcc aatagttggt cttagtaaat ctaatctagt tgtgttttgt ctacgtaaag
    11221 gcccttctga agagtctgca acacttatca ctactatgtc agaatcttta cagtcagaaa
    11281 aagttccttt ttctatatgt actttatgtg gcagatatga aactgcatca gctaaatcta
    11341 aagcttgagc ttttgattta gattcatcta tatcaatcat aaagagttca tcacaaactc
    11401 cttgagttat taaactaaat ccacaatgag aaccaacatg ccctgaacct acaatagata
    11461 tttttcttgg ctttattgcc attttaaatc actcccccta aaataacgat acattgaaaa
    11521 ttatagatgt tattaaaagc tgtttttgaa tattttaata ttctattatt tcagaaaatt
    11581 tatttaatat gattttatac taaaattttt aaaaaagcaa tgttaatata ctctctatta
    11641 gtgaata
//
LOCUS       DAEQAF010000108        11254 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.112, whole genome shotgun sequence.
ACCESSION   DAEQAF010000108 DAEQAF010000000
VERSION     DAEQAF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11254
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.112"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            272..2292
                     /locus_tag="KRN00_003118"
                     /pseudo
     CDS             272..2292
                     /locus_tag="KRN00_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            2661..3881
                     /locus_tag="KRN00_003119"
     CDS             2661..3881
                     /locus_tag="KRN00_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBH1828970.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKADYIFGLHVMPHIETGLIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHISDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3918..5267
                     /locus_tag="KRN00_003120"
     CDS             3918..5267
                     /locus_tag="KRN00_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1828971.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            5324..5944
                     /locus_tag="KRN00_003121"
                     /pseudo
     CDS             5324..5944
                     /locus_tag="KRN00_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(6052..8385)
                     /locus_tag="KRN00_003122"
     CDS             complement(6052..8385)
                     /locus_tag="KRN00_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBH1828972.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLCLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSRLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(8382..9065)
                     /locus_tag="KRN00_003123"
     CDS             complement(8382..9065)
                     /locus_tag="KRN00_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1828973.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            complement(9136..10377)
                     /locus_tag="KRN00_003124"
     CDS             complement(9136..10377)
                     /locus_tag="KRN00_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1828974.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            complement(10388..11074)
                     /locus_tag="KRN00_003125"
     CDS             complement(10388..11074)
                     /locus_tag="KRN00_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1828975.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKNLLTVR
                     RMGYKWNVIK"
BASE COUNT         4171 a         1575 c         1460 g         4048 t
ORIGIN      
        1 caatagaatt tattaaaata aatttttttg ggtgtatatt ataatttaat cgaatagaaa
       61 tgaaaaatat acatacagtt taagttttaa gcaacaatta gggggatttg gtgacaagat
      121 ttttaattat aagaaagaaa gtgtcttaat gcaactttta taaagtcatt atagacactt
      181 tcttttttat ttgataaatt taaattatca aaattatatt gctttataca actattttgt
      241 tggaaactat ttattatata aggagaaata aatgaaaaaa tcagtagctc tggtaaatga
      301 tagtagaaaa gatttaatag actttttaga aaataatttg aaattagttt ttggagattc
      361 tataaatatt aatagatact tcataaatga aataaatgat aatgatatta taaatgatga
      421 tgtgatatta gtaatgtcag tagaaagatt agacaaaatt ataaataata tactagataa
      481 gaaaaaagtg attgtggtaa gaagaacttt tagggaagat aaaatttata atctactatc
      541 tttaccacag ggtacaaacg ttctaatcgt aaatgattct gatgaaacta ctctagaaac
      601 tataagttta ttttataaaa ttggagtgac taatattaga ccaattccat atatgaatga
      661 taataactat aaaaatataa aaatataaaa atagctataa ctccaggagt tccagaaaaa
      721 gtacctagct ttatctcaga tatatttgat ttaggtcaca gatatataga tatctctaca
      781 tttatagaaa taataaattt attacaaatt gattcaaagg aaatacaatc taatctagtt
      841 aaatactcag aagaaataat aagtttagat actggtataa aagataaata taaggaatta
      901 tttttaaaaa tagaagaatt agatacaatc ttgaatttat caaaagatgg tatattattt
      961 acttcaaaag atggtgaaat aaatacatat aatagtaaag taaaagatat tttagacata
     1021 aatgaggata tatatggaaa atacattgag gatatatttg tagatagttt aaaagtttta
     1081 ttgagtgaga aagagatact agataaagtt gtcgtattca ataagaaata tataaatgta
     1141 aataaaaaaa acatatacaa tagagatgaa aaaatgggca catattatag tttacaagaa
     1201 ataacataca taaaaaaatt agaacaaaat ctcactaaaa aattaagaga aaaaggacaa
     1261 atagcaaaat atacatttaa ggatataaaa acaaatagtc ctaaaatgtt tgaatgtata
     1321 gatttagcta agaaggtttc taaatctgac ttaagcatac ttatcagagg tgaaagtgga
     1381 actggcaagg aactcatagc tcagtctata cataacaact caaatagaaa aaatcaaccc
     1441 tttatagcag taaattgtgc agctgttcct gaaaatttat tagaaagtca gctattcgga
     1501 tatgacaaag gaacttttac tggaggtcta aaagatggaa aacaaggatt atttgaactt
     1561 gctaataatg gaacaatatt cttagatgaa ataggcgata tgcctttaga attacaaaca
     1621 aaactactta gagttcttca agagaaacag ataatgcctg ttggttctca caatgtgatt
     1681 aatatagatg ttagaatcat atctgctaca aataagaatt tagaacaaat gattgataat
     1741 agccaattta gagaggattt atattatcga ttaaatacaa ttccaataaa tatacctcct
     1801 ctaagagaaa gaaaagaaga catattaatt attatggaag atttaattaa taagaaatta
     1861 gtaatcacac cagaagcaaa aaaacttata caaaactata tgtggaaagg taatataaga
     1921 gaactccaaa atgttacatc ctatttaaac attatgtgtg aagatattgt attagagaaa
     1981 gatttacctc caaacttaag gtcttcagat aacaaaaata catcattaaa actaaaatat
     2041 agtaagaatg atatattgaa tatattagag atactaattt taaataagga atcagatgtt
     2101 ggtattggta gaggattaat tttaaaagca ctactcgata agaaccttca aattacagaa
     2161 ggaaaaatta aaaaaatatt tgaatatcta aaaaaagaag aacttataat ttgtagttca
     2221 ggaagatatg gaagtaaaat aactcaaaaa ggagaagatt tttacaataa attaaaatat
     2281 aaaggtctat aaaattataa tttatcaaac aaagaaatct attcaggatt aaagtactcc
     2341 ttcaataggt ttttttattt ttcaagtacc ctaaaattat aatttatttt gtacataaat
     2401 aataggaatt aataggaata ggataatttt tttatttcct atttttttta tataaactag
     2461 catataaaat atattttctt caaaataata ttttttactg aaaattgaaa ctatgcaatc
     2521 attttttata ctatacatat agataaatga ttatatttat tcaatattct tataaaaaac
     2581 aaaattttcc atcgaaaatt atggcataat aattgcttat tatattaata aaacaataaa
     2641 aagcaattgg aggaataaaa atgcaacagg ctttgaaatt aaaatatcaa accaaagaat
     2701 taggaaaaga ttttgtaata gaaagttgta attctataaa accatggctt ataaacataa
     2761 gaagagaatt acataaaatt ccagaattag ctcttgaaga aaatcttact aaacagaagg
     2821 taatttctta tttaaaagaa atcggaattg attatatgga atttacaaaa cacaatggaa
     2881 ttatggcata tattttaaaa gaaagtgcag ataaaacgat ttgtataaga gcagatatgg
     2941 atgctcttcc tattgaagaa gaaaacaaca taccttataa atcaatacat tctggaaaaa
     3001 tgcatgcttg tggccatgat gcacatacaa ccatgctact tggagcatgt aaagttttac
     3061 attcaataaa agataaactt aatgtaaatg taaaattctt atttcaacca gcagaagaag
     3121 gttttggagg agcaaaattt ttagttgagg atgggtgttt agaaaacccc aaggccgatt
     3181 atatattcgg acttcatgtt atgccacata tagaaacagg ccttatcgaa acaaaatatg
     3241 atacattaaa tgctagtgta gacactataa aaataagtat caaaggtaaa agagctcatg
     3301 gtgcatatcc tgaaaacggt attgatgcaa tagttacagc ttcacaaatt gttacatcat
     3361 tacaaactat aataagtaga aacttagaac caaataatgc tgctgttttg actataggta
     3421 aaatatatgg tggtgatgca cacaatgtaa tatgtgaaga tgtaaaatta gaaggcactt
     3481 taagaacctt aaatagcaaa acaagaaact ttatgattga taaaatagct aaaattgttg
     3541 gagatactgc atctgcattt ggttgtgttg ggactttaca tataagtgat gaaaactatc
     3601 ctgctgttat aaatgaaaaa gaattagtag atacagttat atcaaatact aaagaattac
     3661 ttggagagga aaaatttata ttgagaccaa acccgtcttt aggtggtgaa gacttttctt
     3721 tttacacaga acattgtaaa ggagcattct tccatttagg atgtaaaaat gaggaaaagg
     3781 gcttaatttc acctcttcat acctctagct ttaatataga tgaagattgt ttaccaatag
     3841 gtgttatgat gcatgtaatg aatactttgt attttaatta gtacagtaat taataaaaga
     3901 ataggagata aattaatatg gaaaaagcta agaaattagg tctatttagt atgatattat
     3961 tagggattaa tagcataata ggttcaggta tattcttact accaggtaaa gtttataatc
     4021 tagcaggtca aaacagtatg tttatataca tttttgctac actcttagtt ctatcaatac
     4081 ttttatgttt tgcagaagtt ggaagcatgt ttgataagaa tggaggagca tatctatact
     4141 ccaaaaaagc ttttggagat tttataggat ttgaagttgg tacaatgtct tgggttatta
     4201 gaattatatc atggtctact ctagcagtag gatttgcaac agctttaggt tcattttggc
     4261 cagaatctgc cactgaatac aaaggttata tagctgcaat actcgtaaca ctactttcaa
     4321 taaatagctt atttggaatt aaaagcacaa agataatgaa taatgtaata actatagcta
     4381 aattagtacc attaatagtt tttataatag ttggaatatt ctttataaaa tttgtaaata
     4441 ttgttccttc aggaaatgta gttaactcta gtatgggtcc agccattata ttagtatttt
     4501 acgcatttac cggctttgaa tcatttattg tggcaagtgg agaaatggaa aatcctaaaa
     4561 aaaatcttcc agtcgcatta ataaccacaa tatttatatg tgcaataatt tatatattaa
     4621 ttcaaattgt ctgtatgggt atacttggag atagactatt tgaaaacagt attccaattg
     4681 cagatgcttc aagtgtattt ttaggcaatt atggtaaagt tttcatatct gtagcaacat
     4741 taatatctat atttggtata aatataggtt catcaatagt aactcctaaa tgtggttctt
     4801 ctctagcaga agaaggttct cttcctgcat ttataggaaa aacaaataaa tatggtgctc
     4861 catatgtagc aataataata tctttaattt gttgtatacc acttgtgcta actggaagtt
     4921 ttgaacaact tgcagtaatg agtgtaattg caagatttgc tcagtatata ccaacttgtt
     4981 tatcagtaat agttttaaga aaaagaacag atgttaaggc ctcttttaag attccatttg
     5041 gtcctgttat accaatggta gctattttag gtagcttatg gttgttacaa caagcttggg
     5101 cagaagatat ttcaaaacct ataactcaaa atagagtttt aataggatta ggggcaatgt
     5161 tgttaatagc tcctctatat atatttatga aaaaaaataa agaaatcgag cataaaaata
     5221 aatcagagga ttctaaatta tatatttcga gagaaaaaat tcaataatat tttacaaact
     5281 atttaaaaat tatttttcta atactataga aataattaga aatggagatg ttgcatatct
     5341 aaaagtagtt gataacacgg atattggtac ttttatagat atgggactta caaaagacat
     5401 actagttcct tttaaagcta agacttatcc attgtttaga gatgaaaaat atttattcta
     5461 tatatacttg gataaaagcg gaagaatagc tgctactaca gacatagatt catatttaga
     5521 aacagaccat acttacaatg taggagatgt tgtaaatgga gttgtatatg gattccaaac
     5581 caacaactct gctatgatat gtgttgacaa taaatatgct ggtgtaatcc ttcataatga
     5641 atactttaca gaattaaaag ctggggatgt tcttgaaaat ttacatgtta taaaaatata
     5701 cgatgatggt aaattaggac tttctcctag aggaaacaga aaagatgaac ttgatacctt
     5761 agaaaataag attttaagct atttagaagg ttcagatgga tatatgagat tcaatgataa
     5821 atctgatcct aaagatattt ctatcttatt taattcaagt aagaaaaatt ttaaacgtgc
     5881 tcttggagta cttatgaaga aagacttaat ttatcaagat gaagatagaa cttatctaaa
     5941 gtaaattata taacacaaaa atcgaagtaa attatgaaag atattttcta tttcatattt
     6001 acttcgattt tttatttaaa ttactacctc tatttaaatt actacttata tttattgtgc
     6061 atttactacc tctattatgt ctaattcaca aatcttttta attggttttc ttactgcaag
     6121 caaagttatt attatcatag ttactacaat gataaacagt aaatcaaaag gtatttgcca
     6181 gtctatatgg aattttaatg ttactaagga tacaaatata tatctatgta atattaatcc
     6241 aagtacactc cccaataaac agccacttac agcatatgta cttgattcta ctattaccat
     6301 ttttcttaat tgcttattgg acatgcctat tgcacgcata ataccatagt aatttattct
     6361 acttgtaacg cttatattca tactgtttat gatattaaac atacttataa tcgcaattat
     6421 aaatacaaac ccatatacaa aaactgccat agtgtaaaat gaatttttag cctctaagtt
     6481 accttgtcgc ttatctcgaa cctctaaatt atcatctaga acatttctta tattttggat
     6541 taaatcttca ggagcatctt catcaacttg agtatcaatt attatatagt cttttatatc
     6601 tgttatacta gtaaaagtat tttcagatgt tataatattt ccaatatatt tgtctttaac
     6661 atcaaatgaa attgaagaaa gtatacctgc tacctctatc tctttcttag aatttccatt
     6721 tttaatatat atcttatctc caatattaaa cccatgacct tcttctacca atccgatatt
     6781 ttctgactct aatttatctt cattgatttc cccttttact agatactttt tggcccagtc
     6841 aaattgattt ttttcataag aaattagctg agatgttgcc tccttattat tgtatgtagc
     6901 ctctacatcc gtcatcattc tactgtatac tttttttatt cctttgatat tacttatttc
     6961 attaatatcg tctttagtaa gaacagactt aaagtcagcg tcaacaatag atatatgagc
     7021 agcttctggt tttataggtt taagtgcctg atacataaag tctataaata cactaaaacc
     7081 taaaaacaat acaatactaa tagcaaatga agaagtcata agtataaaag atttttttct
     7141 tgaaaaggca tgatttattc ccatagaaac atcaatttta gaacttcctg cgttagcaat
     7201 tttacttgct tttccactag ttaaaatttc tttgaacatt agattaccac gtatagcact
     7261 tagtggagac accccagaag ctttttttgc tggaacaata gctgataata ttactgttaa
     7321 aaatcctact attattccaa acacaatacc aataaagcta acctttaaaa ttggcatcga
     7381 accaaataac tctgtattca catatttgag aaatatagag gatataatgg ttacaataca
     7441 tcctaataac aatcctagtg gaatagcctt tacacttaga attaaacttt ctaaaacaac
     7501 aaattttttg acttggagtt ttgatgctcc caagcaacgt aatagtccaa aaaactttat
     7561 tctctctatt acacccatat taaagctatt atatatcatg ataatacttg ctattaacac
     7621 aagtataaaa agtcctcctg ctgttaagta aagtggttta gaataatcag agtcaccttg
     7681 acctataata gaaagtaatt tttcattttt accgatttgt ttatcactta aattgaaggt
     7741 attcttaata tcagaagtag cttttctaat attaaccttg tctttaaatg taatataata
     7801 ataatcatat gtttctgatt ttttgatagc ttgtgtacct aatattgaaa gcattaatcc
     7861 atgcttatct gaggctctta atcttgataa tgatgaatat tcacctacta tcttataatt
     7921 tttatttcta ccatctgcta attttatttt gataaaatct cctactttta gattaaagct
     7981 tttaactgca tctacatcta ttaaagtctc attctccaca acaggataac gaccttttat
     8041 tatttctaga cataattgtt ttgctaaatc ttcatctaaa ccttgtatca aaatctcctt
     8101 tgatttaaac tctccattat caatgacttg tcctctacca tagtgagcta tatctactct
     8161 actacttatt tctgatatag cttcttcatt aagattttta agtactatgt gccaatttcc
     8221 atcatctttt ataaattgta ctttttgaca ttgtatagcc atgtctgcta gtccaaaaat
     8281 agcagtaact aaacatactg caatgacaat acataaaatt gtagttctat tttttttctt
     8341 atgtaccttt gcatattgtg gtactagttc taaatagctt ctcattctct attcacccct
     8401 aggtctttaa gcattccatc agaaacctgt agtatcctat ctgctgtaga agctatattt
     8461 gtattatgag ttatcataat aatagtttgg ttatattttt ctgctgtcac ttttaaaagt
     8521 gaaattacat cactgctatt tttactgtca agatttcctg ttggctcatc tgccaatata
     8581 attgatggct ttgtaatcaa tgctcttcca attgcaaccc tttgttgctg accaccagat
     8641 aattgatttg gaagatgact ttttctatct ttaagaccta aaattgtcaa tacttcatct
     8701 agataaatag tgtctggttt tttgtaatct agtagtaaag gaaatattat attttgttcc
     8761 acagttaatt cgggtataag attatatgat tgaaagataa aacctatatt acgacgtcga
     8821 aaaatagtct gtttttcttc tttcattgaa catatttctt taccatcaac aaatattttt
     8881 cctgaggttg gagtatcaag acctcctaaa agatttaata atgtactctt acctgagcca
     8941 gattctccaa ctacagtaac aaactctccc tttgaaactg taaatgatac atcttttaat
     9001 gcctctactt ttgtatatcc atttccatat gttttacata aattattaac cacaagaata
     9061 tccatttgct ctatctcctt tctgatgatt aatataagaa taattcatac accttactgt
     9121 aagatgtatc ctatcttaca tattagtaag ctttaaaaaa cttagagtaa atgtacttcc
     9181 ttgtaaaaaa ttactttcta cagttatggt tccattgtgc tgttctatga tagatttaac
     9241 tagtggcaac cctaatccaa ggccttgatt actttttgaa aacttactcc tataaaatct
     9301 tttaaatata tgatgtatat cttcaatatg aattccattt ccggtatcac tcactgaaat
     9361 aatagttgtt ataggtgttt caacccattc tatcattatt ttatcgttct cttttgtatt
     9421 atctaatgca ttttttataa ggttgcttaa agcttctgat atccattcat aatcgcaaaa
     9481 caagtttgta ttttctagac ctcttataga gatactcttt ccttcttttt ctgctctagt
     9541 ttcaaaacta tataaaattt tagtaatcaa cttttttacg ttaacactag ctttgttaag
     9601 aattattgtc tttgaatcta tctttgtaat ctttaacaag ttttgtatca atgattctat
     9661 acgctctaat tcattttgac tcttctgcac aaaattctca acaatttcac tattatgact
     9721 ctcttcctgc aatatttgat tatacatcat caatgctgta agtggagttt ttagttgatg
     9781 tgatatatct gaaattgtat ttttaagaaa ttctttattc tgcttttctt tcaatatatg
     9841 tgtgtttaga gatgttgaca tagcatctat tgaaccaaat aactttgata aactaccttc
     9901 ttcataagta tttaaccgta catttatatt tccattcata aatgaatcaa ttttataact
     9961 agcttcttct atcttgttct gttgcctaaa aaaatacaca tacaatataa aaataatcat
    10021 agtaaagaac acaaataaat acaaaaacat agtttttata tatttacctt gaaacaattt
    10081 cacacttggc ataaaactat catctgtacc aaagtcatat ctagctgtat ttaagatttc
    10141 ttttcctttt aaagtatatt tatcttcatt agtagtaaat actgctggta tttttgattt
    10201 atcaacaccc atactattta agtatccagc tatattataa tcatgttcta acagtgcact
    10261 tttataatca ttagttatat ttataactac tatttgacct actactataa acatcaataa
    10321 aacggatata atcaccaaaa aaaatatttt tatgtcttta ttagaaaata ccttcatatt
    10381 aacaccctca ctttataaca ttccatttgt aacccattct tctaactgtt aatagatttt
    10441 ttggattttc aggattatct tcaatcttat ttcttaacct tcttacatat actgacagag
    10501 tattatcatc tacaaaacta ccatttccat cccataactt atccaatata ttttttcttg
    10561 taagtacaat atttttattt ttcataagta agcataataa tttatattct gctgtagtaa
    10621 gttcaagctc aatttcattt ttaaaaacac gattttcaag taatttaaca gtaatattat
    10681 ttgattttag ttcagttaca ttttcacttg taaaattata acgtctaagt aaagctttta
    10741 ttcttgaaat taactcattt aatttaaaag gttttgttat gtaatcatct ccacccatat
    10801 caagtcccat cactacattt acttcttcat cagaagcagt taaaaatatg attggtacat
    10861 tagaagcttc tcttaccctt ttacaaatat caaaaccatc accatcaggt aaggatacat
    10921 ccaaaagcag taaatcataa tttttttctt tataaatttg caatgcttct tctactgttc
    10981 ttgctacatc aacactaaat ccattctttt gtatagaata ttctaatcca tatatcaaac
    11041 ttaaatcatc ttcaaccaac aatatactac tcatctcaat cacttccatt tttttatttt
    11101 ttactttata tatattatat acctaactta ttatattttt actcttttaa aaatacaata
    11161 ccttgaaatc aatgatttaa atattttaaa attattttta tatgatttta tatagttaat
    11221 ttaatacttt gaaatcttaa taataaaaaa agct
//
LOCUS       DAEQAF010000109        11234 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.113, whole genome shotgun sequence.
ACCESSION   DAEQAF010000109 DAEQAF010000000
VERSION     DAEQAF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11234
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.113"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..1041)
                     /locus_tag="KRN00_003126"
     CDS             complement(<1..1041)
                     /locus_tag="KRN00_003126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828976.1"
                     /translation="MYIEELKQNLNNKIGDIINIYLKIYWNRISNRGEKNLYNIYFNR
                     EIKRVLYNKYLENINIDKRDISVVYDCIINDLNSEIDKRIRNSNINELMAILYGIACF
                     QAEFHGRVFITLNNNTSNFSNILHIEKDILRYIERNLKKRFIVDSISATDKSSIQYLI
                     EKCMNFSSDSDNQNNFGVKLFTDVYMMSLIITNLIAEKNMLLSGLCDDISVWINDYMI
                     YNNLDRYYDNEIIYKEYIEDLNFDIRDYDSKIIEKLKNNFFKSYGFRIETIERFLNST
                     NKTIKDTELVHLVEEKTLVKAFCDDSGADIEEIRFLIKYLTITKSIEYDKLKSMENYS
                     NRILEKAFININN"
     gene            complement(1128..2255)
                     /locus_tag="KRN00_003127"
     CDS             complement(1128..2255)
                     /locus_tag="KRN00_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBH1828977.1"
                     /translation="MTIPKLEPSDRKREFDKYTSQQINKVVYNYLFEKNMSNRKIEGE
                     ILNLSSKQNKGYQAMSILHHLGINKNHKGVFMGYTIDKAIEVLKEDEIYFKQIINILL
                     ESKNINKYPIIVDSWELLDEKIALKTIDKSTLKHNRTGVPIEIRHFFEINNLGKNEKK
                     NVNFRYDDNYYSAVIEMDKLENPRSRIIWKSKFRDLLRNIFPKYYEKFLEDEIEGKTN
                     LPKIRFVKFDSNNFDIEFIFTSEIEDDVLEEISQDNPLDIDTINIELETEIRKEGKVK
                     YVYGKQYERNPKNRIEAIKYHGTKCVVCGFDFEKTYGNRGKGYIEIHHIRPLSSVGKE
                     SNINPKTDLVPICSNCHRMIHRKKDSVLSIDELKQLIKDKK"
     gene            complement(2501..2776)
                     /locus_tag="KRN00_003128"
     CDS             complement(2501..2776)
                     /locus_tag="KRN00_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828978.1"
                     /translation="MYDEIIEIYFDYWINEHMYRDILEKDKYYIESWKEIITTNELLE
                     KSLLEEDRRYVLVELNDLFNSLIEFERELSYKFGFKAGVKFIIELLK"
     gene            complement(3024..4358)
                     /locus_tag="KRN00_003129"
                     /pseudo
     CDS             complement(3024..4358)
                     /locus_tag="KRN00_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(4371..5114)
                     /locus_tag="KRN00_003130"
     CDS             complement(4371..5114)
                     /locus_tag="KRN00_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828979.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNKSTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNINNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKASFDWIMSPNNFIK
                     ILEGNYQDKSINVKVDADAYSPDDSQLKW"
     gene            complement(5135..5449)
                     /locus_tag="KRN00_003131"
     CDS             complement(5135..5449)
                     /locus_tag="KRN00_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828980.1"
                     /translation="MADTNNLEVLKTLQATLNILVKQEQEAQEKAKGYKEIQTYRRDK
                     AQLITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            complement(5453..5647)
                     /locus_tag="KRN00_003132"
     CDS             complement(5453..5647)
                     /locus_tag="KRN00_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003450825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1828981.1"
                     /translation="MKLKLKRIEKGIKQYELAQKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKGE"
     gene            5791..6651
                     /locus_tag="KRN00_003133"
     CDS             5791..6651
                     /locus_tag="KRN00_003133"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1828982.1"
                     /translation="MINNTIGEKIKQYRKSLNLSRDELANKIGCSVHAIAKYEQNQRK
                     PNLDIIKKISTALSIPINRLIIEENDLDTSTNNYTNLKEFDSVVKTFDNYSAKLIGNN
                     ISKFRNINNISIKELSEKINCSENEVINYENGTKMPRIEILKKIALATYANIEDLFGF
                     PLEEIKIDNQTILYRNPQTGYIINDFLIDFINKDIDIDNTPVSHYIDKSEFDLVIHIL
                     ENYGYDINTDYKTKFEITDNADTIKPINLNFSDFKNFSKNLNWVINGLVEKFIQENSN
                     GLVEDEDEEY"
     gene            6740..7492
                     /locus_tag="KRN00_003134"
     CDS             6740..7492
                     /locus_tag="KRN00_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1828983.1"
                     /translation="MNKSYIPKYTHKFPTNLPHGDKKYTLTYIRRMISEFVYDMGNLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVSDINIINKITNPLEKAI
                     IVNLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDEYNYKSYKELFKNGN"
     gene            7482..8648
                     /locus_tag="KRN00_003135"
     CDS             7482..8648
                     /locus_tag="KRN00_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBH1828984.1"
                     /translation="MATKRANGEGSIGKYKDGWRSRIMIGYNEDGKPIRKEFYGKTQK
                     EVKDKLDAYKKQYYLSSDISDDKITLEHWFYNWLFEYRIKDLKPKSFERYESIYRNYI
                     KDTDLGNVKLKDLRVSHIQKYYNRLLDSNKSIPTIRQINTKLKTCLSEAEKQGLIQRN
                     YCTMVNIPVEKKENKLEILTLEQQKSFIKAIEGHKLEVLFLVALGTGLRLGELLGLKW
                     FDIDFKKSNLTVKRTLQRTYFIDKNGNRELKVLEQEPKTSNSYRTVPIPKDVLNKLKE
                     HKINQNTDILKAGELYRNDNYVFCNELGISIDDKRPLRNLKSILNSLDIEPIKFHGLR
                     KTYATRLFENDVPPKTVQVLMGHYDISITLNIYTQVMEDKKVEAVEKLDKIFSL"
     gene            complement(8766..8996)
                     /locus_tag="KRN00_003136"
     CDS             complement(8766..8996)
                     /locus_tag="KRN00_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828985.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVSDMHCKGHIYLSQELMLENGLMYHKGYPR"
     gene            complement(9002..9478)
                     /locus_tag="KRN00_003137"
                     /pseudo
     CDS             complement(9002..9478)
                     /locus_tag="KRN00_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433745.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
     gene            complement(9478..9693)
                     /locus_tag="KRN00_003138"
     CDS             complement(9478..9693)
                     /locus_tag="KRN00_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBH1828986.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            complement(9993..10342)
                     /gene="ssrA"
                     /locus_tag="KRN00_003139"
     tmRNA           complement(9993..10342)
                     /gene="ssrA"
                     /locus_tag="KRN00_003139"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(10500..10955)
                     /gene="smpB"
                     /locus_tag="KRN00_003140"
     CDS             complement(10500..10955)
                     /gene="smpB"
                     /locus_tag="KRN00_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBH1828987.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
BASE COUNT         3874 a         1784 c         1162 g         4414 t
ORIGIN      
        1 attatttata ttaataaagg ctttttcaag tattctatta gaataatttt ccatagattt
       61 taatttatca tattctatag atttagttat agttagatat ttaatcaaaa atcttatttc
      121 ttcaatatca gcacctgaat cgtcacaaaa agctttgaca agagtttttt cttctaccaa
      181 atgtactaat tctgtatctt taatagtttt atttgtagag ttcagaaatc gttctatggt
      241 ctcaatccta aaaccatatg atttaaaaaa attattcttt aatttctcta taattttgga
      301 atcatagtct ctaatatcaa aatttaaatc ttcaatatac tctttgtata ttatttcatt
      361 atcataatat ctatctaaat tattatatat catataatca tttatccaaa cactaatatc
      421 atcacacaat ccacttagta gcatattttt ttctgctatt aaatttgtaa ttattaggct
      481 catcatataa acatcagtaa ataattttac accaaaatta ttttgattat cactgtctga
      541 tgaaaaattc atgcattttt caattaaata ttgaattgaa cttttatcag ttgcacttat
      601 agaatcaact ataaatcttt tttttaaatt tctttcaata tatcttaata tatctttttc
      661 tatatgtaat atattactaa agttgcttgt attattattc aatgttataa atactctacc
      721 atgaaattct gcttgaaaac atgctattcc atatagaatg gccataagct catttatatt
      781 actattccta attctcttat ctatctctga atttaagtca tttattatac aatcatagac
      841 tacactaata tctcttttat ctatattaat attttctaaa tatttattat ataataccct
      901 ctttatctct ctattaaagt atatattata taaatttttt tctcctctat tagatattct
      961 attccaataa atcttcaaat atatgttaat aatatctcct attttattat ttaaattttg
     1021 tttcaactct tctatataca ttgtagtata accccactta ggctttagat ttttttcatt
     1081 atattacaaa tttcaatcta ttatataaat tcaaaaagta tcaaatatta tttcttatct
     1141 tttataagtt gcttcaactc atctatactt aaaacactat cttttttcct atgaatcatt
     1201 ctatgacaat ttgaacatat tggcactaaa tctgttttag gatttatatt actttctttt
     1261 ccaacagaac ttaatggtct aatatgatga atttctatgt atcccttacc tctgtttcca
     1321 tatgtttttt cgaaatcaaa cccacataca acacactttg taccatgata ttttattgcc
     1381 tctattctat tcttaggatt acgctcatat tgttttccat aaacatattt aacttttcct
     1441 tcttttctaa tttcagtttc taattctata ttaatagtat caatgtctaa aggattatct
     1501 tgacttattt cctctaatac atcatcttct atttcagaag taaaaataaa ttctatatca
     1561 aaattattac tatcaaattt tacaaatctt attttaggca aatttgtttt tccttcaatt
     1621 tcatcttcta agaatttctc ataatactta ggaaatatat ttcttaataa atctctaaac
     1681 ttagatttcc aaattattct acttcttgga ttctctaatt tatccatctc tataactgca
     1741 ctataataat tatcatcata tctaaaattc acatttttct tttcattctt ccctaaatta
     1801 tttatctcaa aaaaatgtct tatttctatt ggaacccctg tcctgttgtg ttttaatgta
     1861 gatttatcaa ttgtttttaa agctattttc tcatctaata actcccaaga atcaactatt
     1921 ataggatact tatttatatt tttactttct aaaagtatat taatgatttg tttaaaatat
     1981 atctcatctt ctttaagcac ttcaattgct ttatcaattg tatatcccat aaaaacccct
     2041 ttatgatttt tatttattcc taaatgatgc aatatactca tcgcttgata acctttattt
     2101 tgttttgatg ataaattcag tatctctccc tctatctttc tattactcat atttttttca
     2161 aataaataat tataaactac tttatttatt tgctgtgatg tatatttatc aaactctctt
     2221 tttctatcac taggctctaa cttaggtatt gtcatattat cctcctcaat tgattatttt
     2281 agattttaat aaaattattg tatcatatat ttattattaa aatatgttat gttatttatt
     2341 taaatataaa aataatacaa tgtaattgat tccacaaaaa attaaagagg gcatccttaa
     2401 taccctcttt ataaaatata tttaattcaa ggtgttatag tacaatttat tcataatctc
     2461 aatctacaat ttaattaatc tactgaaaca tacaaaataa ttacttcaac agctcaatta
     2521 taaattttac tcctgcttta aatccgaatt tataactaag ttctctttca aattctatta
     2581 atgaattaaa taaatcattt agttccacca atacatatct tctatcttct tctaataaac
     2641 tcttctctaa caattcatta gttgttataa tttctttcca actttcaata tagtatttgt
     2701 ctttttctaa aatatctcta tacatatgtt catttatcca ataatcaaaa tatatttcta
     2761 taatttcatc atacatgtta gtacctcctt gactttcatc tggcacttaa tatatactta
     2821 acttgtgtag gttagtgtac attaagtacc taatttataa aggtagttgt tatatttata
     2881 tggcagctac ctttttctaa taaatttttc aatctaaata ctatatattt taaatcttta
     2941 ttgcatacaa ttaaggatta tatactttgc ttctagcact ccttaaacaa tagtttatat
     3001 atcacttaat aaattatatt ttttcatacc tcctttacct tcttacattc cttaaaagaa
     3061 aacaaacttc ctatatacca ataaggtcta aagcctgatt ccccatctct atttttagca
     3121 actataattt cacttaaatt agctccaaaa cctttttctc tacgtcttaa ttcttttata
     3181 tcctctattc ccattgtctt acaataatca agagcctctt tctctgtagg tctatgaata
     3241 tatatgactg aattagaatc catatatatc tgttttgaac ttctcattac tctatctcct
     3301 tttggtcttt catccttcaa ttcatcattt aattgagcca actgtataat tggaatatta
     3361 aagtctaaag taatcttttt tatttgcctt gataaatcag caaacttagc ttctccaact
     3421 tctttacctt cgtaatccaa aatctgaaga taatcaatta taacaacatc tggtttaata
     3481 ctttttatct ccctcttaat tcctgatatt gtattcactg aatcattaat atagagatta
     3541 ttctcctgat ttaaaatact taaagcattt atgtatttaa ttatttcttc ttcatttagt
     3601 tttctattct tcatttttac aactgatatt cccgttaaag aagctatatt tctaaacaaa
     3661 atttgtatat cactcatttc cccacttata aaaagtactt ttttaccttg aaataccaca
     3721 tttctcatta tctgtaaggc tagtgctgtt tttcctcttc cacttttggc tgctattgta
     3781 attaattcac cactatatag acctccaata gtttcatcta aaaattttat tcatatattg
     3841 ataccttctt caatttcatc atttatgtat tcaaaagctc tttctgatat agctgttata
     3901 ctagaatcct tcttaaccaa tttctgatta acttcattaa cgtatttttc taattgatat
     3961 ataagtgtat tatcatctat ttcacctaat ttaaatttat taaatttata aattatattt
     4021 ctatttttat atttttcaat aactatctca atataatggg atacattacc tatagttgga
     4081 actattgttg atagttttgt caaataactt atacctccaa cataatctat aagccccttt
     4141 ttctttaaat cttctgtaag agttattatg tctataggct catccctttt atgtatatct
     4201 ttcactgaat tgaatatatg tttgtgttct tgatgataaa acatatcttc acttattaat
     4261 atctcaacct cttctatttt cctcgaatct agtaaaatac tacctaatat agattgttct
     4321 gcttctgtgt tcttaactaa attactcata ttatccataa tataaactcc ctaccacttt
     4381 aattgtgaat catctggact atatgcatct gcatctactt taacattaat tgatttatct
     4441 tgataattgc cttctaatat cttaataaaa ttatttggac tcattatcca atcaaaactt
     4501 gccttccaac ctttttcatt gcttccattt aaaaagctag ttttactaac tatatgaata
     4561 atttctaata cagtctcttt atcatattct tttatcctag cattaattac tttttttcta
     4621 gcttctgtaa gtttctttac ttttgatagt tctgtacaag taatattgaa tttttctata
     4681 atttcactgt atattttact tttttcatta tttatattct tgttagttgt tagttgcttg
     4741 ttaattgcat gttgattagt ctgttgattt tcttcattag attgatatag ctcccagttt
     4801 tcaatagtta taagcctatt tttgtttgtt gatttatttg ttagaaatcc atatctttca
     4861 aatttcttta aagcagttct tacattctga atacttacat cttttgaaca catatttgct
     4921 atactttcca aagatgttat taactgtcca gatttaactt catattcttt acctccataa
     4981 acccatttat taggcttatg attaactgac agtaataggt ttatgagtat atctctttgt
     5041 ttggaattac aatctttata tagtgggctt tcttttatct ttctatgaag ctttatccaa
     5101 cctagattac tcaaatacta tcacccactt aagcctataa ttttatgcca tttgcatttt
     5161 caataaacca atcatctagt ttatttttta ttatatacac tctattatct atccatatac
     5221 aaggaaatcc tttattttta gaatgacata actgtctaaa ttttgattcc cctatgggat
     5281 aaattttgga agcttcttta caagtgataa gttgagcttt atctcttcta tatgtctgta
     5341 tctccttgta cccttttgcc ttttcttgtg cttcttgttc ttgtttgaca agtatattca
     5401 atgtagcttg tagtgtttta agaacttcca gattatttgt atctgccata gatcattccc
     5461 ccttatcaaa aaataattct tctacacttg tatctagttc ttgagccaat tttaacatca
     5521 acatattact tggatttttg gatttgcctc tttctaaaga agataaataa tatcttgaaa
     5581 tgccaacttt ctgagctaat tcatattgct ttataccttt ttcaattctt tttaatttaa
     5641 gcttcattga tttcctcctt cctcacatac ccatattgtg cctttttatc tttctataaa
     5701 acatagaata acacccattt cgtgctttgt caatatattt aagtgtatta atacacccat
     5761 ttcgtgctat aatgtatttg aggtgaaatt atgataaata atacaattgg agaaaagatt
     5821 aaacaatata gaaagtcatt aaatttgtca agagatgaac tagctaacaa aattggttgc
     5881 tcagttcatg ctatagctaa atatgaacaa aaccaaagaa aacctaattt agacattata
     5941 aaaaaaatat ctactgcttt atcaattccc ataaatagac ttattattga agaaaatgat
     6001 ttggatactt caacaaataa ttatactaat ttaaaagaat ttgattcagt tgtaaaaaca
     6061 tttgataatt actcagcaaa actcatcgga aataatataa gcaaatttag aaacataaat
     6121 aatatatcta tcaaagagct ctcagaaaaa ataaattgct ctgagaatga agttataaat
     6181 tatgaaaatg gaacaaaaat gcctagaatt gaaatattaa aaaaaatagc acttgctact
     6241 tatgcaaata ttgaagattt atttggattc ccattagaag agataaaaat agataaccaa
     6301 acaatccttt atagaaaccc tcagactgga tatataataa atgactttct tattgatttt
     6361 ataaataaag atattgacat agataatact ccagtttctc attatataga caagtctgag
     6421 tttgatttag tgattcatat attagaaaat tatggttatg atataaatac agactataaa
     6481 acaaagtttg aaattacaga taatgcagat acaataaaac caattaacct aaacttctct
     6541 gatttcaaaa acttctctaa aaatctaaat tgggtgataa atggtcttgt tgaaaagttt
     6601 atacaagaaa actccaatgg tcttgttgaa gatgaggatg aagaatatta gtattgcaca
     6661 ttttcaaaat atatatttac ttattaattt tgatatagtc ataattagat aagaattaaa
     6721 taaggaagga gctacaatca tgaataaatc atatatacca aaatacacac ataaattccc
     6781 tactaatcta cctcatggag ataaaaaata tactttaaca tacattagaa gaatgataag
     6841 tgaatttgta tatgatatgg gtaacctaga aaataacccc tttacattcc cagaagtaca
     6901 aacattactt gatggtataa ccgtaggtgg acataaatta agtgaccaaa atcaaatact
     6961 aaatataaaa tcatcatggg attatgtaat aaaattaagt aacaaagaaa acttatcttt
     7021 aaataaagat acaatttgct ctatacataa aatagttgca aaagatgaag ctctaatagt
     7081 cggagatttt agaaatggta acataggtat agctggtact actcaatatg aatgcataga
     7141 agccactcta ttaaatgatt tatttgtaag cgacataaat atcataaata aaataactaa
     7201 ccccttagaa aaggctataa tagtaaattt atggttatcc tattgccaat ttttctatga
     7261 tggcaacaaa agaactgcta gacttacctc aaacctaata cttataagta atgatatagg
     7321 agttctatca ataccagcta aacataaaca agagtacaac acattaatgc taaacttcta
     7381 tgaaacacta gaagctgatg aagttataaa attcttatta gagaaatgta ttacattctt
     7441 tgatgaatat aactataaat catataagga gctgtttaaa aatggcaact aaaagagcta
     7501 atggagaagg ctctatcgga aaatataaag atggttggcg ttcccgtata atgattggct
     7561 ataatgaaga tggtaaacca ataagaaaag aattttatgg taagactcaa aaggaagtta
     7621 aagataaact agatgcttat aaaaaacaat attatttaag ctctgatatt tcagatgata
     7681 aaataacttt agagcattgg ttttacaatt ggttgtttga atatagaata aaagatttaa
     7741 aacccaagtc atttgaaaga tatgaaagca tctatcgtaa ttatattaaa gatactgatt
     7801 taggtaatgt taagttaaag gacttaagag tatctcacat acaaaaatat tacaatagat
     7861 tgcttgattc caataaaagt atacctacta taagacaaat aaacactaaa ctgaaaacct
     7921 gcttatcaga agctgaaaaa caaggtctta tacaacgtaa ctattgtact atggtaaata
     7981 taccagttga gaaaaaggaa aataagcttg aaatattgac tcttgaacaa caaaagagtt
     8041 ttataaaagc tatagagggt cataaattag aagtattatt tttggttgct cttggtactg
     8101 gacttagatt aggagaatta ttaggactta aatggtttga tattgatttt aaaaagtcta
     8161 atttaacagt taaaagaact cttcaaagaa catattttat agataaaaat ggaaatagag
     8221 agcttaaagt attagagcaa gagccaaaga catcaaattc ttacagaact gtacctattc
     8281 caaaggatgt cttaaataaa ttgaaagaac ataaaataaa tcaaaataca gatatattaa
     8341 aggctggaga attatataga aatgataatt atgtattttg caatgaatta ggcatttcta
     8401 ttgatgataa aagaccacta aggaatctaa agtctatatt aaacagttta gatatagaac
     8461 ctataaagtt tcatggtctt agaaaaactt atgcaactag actttttgag aatgatgtcc
     8521 ctcctaaaac tgtacaagtt ttaatgggtc attatgatat atcaataact ttaaatatat
     8581 atactcaagt tatggaagat aagaaggttg aagctgtaga aaagttagat aaaatatttt
     8641 cattgtaaaa agcaaataca taaaaatgct atgattccat ataagttaat tataaaatca
     8701 aaataaggat acaaattaat tttatattat cttgtatcct taattcgtat ctcgtttcta
     8761 actatttatc ttggatagcc tttatggtac attaatccat tttctaacat taattcttga
     8821 gacaagtata tatgaccctt acagtgcata tctgatacac cctcacttat aagtttatat
     8881 gtttcagaag tatataaata atccatactt tcttccaagc tcttacctgt ttgtttggaa
     8941 aattctaata tgattttttt atatagtatt tgtaataatg ttttatttgc ttccataatc
     9001 attatacctc ctcttcatac ctaaacttta aatatttatc tattacattt tgattggtta
     9061 tacatatttg ttcatttggt ttatagtatt ttaatctttt taaagcttca tctttttcaa
     9121 taagattatc ttgatacagt tccattgtat tgtaaatctt attatcagca atgccactat
     9181 tataatgtca tatttcatat atattactca tatttctaca ttctattata aaatcaagcc
     9241 attctaaatt ataactattg aagattttta ccttgcagtt ttcttttaat ttatcaatat
     9301 ctaaagaata actatttaaa tatgcttttt tacctctttt tttaaaacgc tctgtccagt
     9361 taattgcttc tgtctttata ctggttacat agaatccttt tccaaaatct aaagaatctc
     9421 ttgaaaaggt aatactaggc gtctttacca cacaatatga accatgatat acaatcatta
     9481 tatcacaccc ttttctttaa gtacttgcat taaatcttcc actatgtaac ctttactttg
     9541 agaatgtagt gcttcatagc aaggtattat atagttatct aaaatatcag tatcatgttt
     9601 aagaagttta taaactcctt ctgaatctat attcaatttt tctgctaaag cttcaatgca
     9661 aaaaatagaa aattctagtt ttctttcatc cattacaaac ctcaactcct atcaagctta
     9721 tataatatat atttttacta attaacaact taaactgtct tacatttata aaaatattat
     9781 atcataaagt agatattaaa attctatgtt acctattatc ataataaaca aataaaaact
     9841 ttttatacaa cctaaatgca ccccaatata cccacaaaaa aacctctttt tctgtggttg
     9901 gggtacggtt ggtggatttc ttctccaaaa taaaaaatac tagtcaataa agactagtat
     9961 tttcaagtat ttcatcattc ttttttcaaa attggtggag acgaggggag tcgaacccct
    10021 gtccgcaaat cttttccttg ctgcatctac atgcttagcc aacttcacta atatctcacc
    10081 tcacatagcg ccaagtggca ggctctatgc ttagccagtc ccaattaatc tacttcaagt
    10141 cgagacaccc ctaaagtagt tccctgcata atgacgtcca gtcttagtcg gcaggaggac
    10201 taagagggac gagcagcaac taggctgcta tcgcgaaatt atcgtctgcg tttattttaa
    10261 agttccccag tttttacgtg acccagagta acacgacatg cagcctcaag ttccaaaccc
    10321 acgtcgaaac ctttacgccc ccttgagtag tttatagtcc agtagacttt tcgcaaactt
    10381 tatcaccatt tttattaaat ttttaatgta tatataatat aatactttta agaataaaaa
    10441 tcaatgttat gttctagata ataaagaatt ttattctaaa aaatacagtt ttatctagtt
    10501 taatacttac ctgtcatttc tctttctata cgtctttgtg catctttctt agccatatct
    10561 tgacgtttat catatagttt tttacctttt gctaaggcaa tctctacttt aactttaccg
    10621 ttttttagat acaaactaag tggtataagt gaatacccct ttatagtagt tgctccaata
    10681 agctttctta tttcatgctt atgaagtaat agttttctaa ctcttaaaga atcaacattg
    10741 aatatatttc cttgctcata tggacttata tgaacttgtt ttaaaaatac ttcgctatta
    10801 tctacagatg caaatccatc acttaggtta actttgcctt gtcttattga ttttacttct
    10861 gttcctttta attcaattcc acattcgtaa gtttcttcta taaaatattc atgtcttgct
    10921 cttttgtttg ttgctaatat ttttttacca gccatataaa tctcaccttc tttgctagaa
    10981 atttcttcca taagtgttag aaatttacta aatatttaat gttgccaaat tatttgacta
    11041 acttgtatga taacatattt aggtatttta gtcaatattt cactgatata ttaagttagt
    11101 taggctatat ataattaagt aatataaatg tatgaaaata gctaaaaaac tacttcgaat
    11161 atacttaata ctaaactaac tctaaccagt aatactaatt tataaatttc aaaacaaaaa
    11221 tattacatat tata
//
LOCUS       DAEQAF010000110        11218 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.114, whole genome shotgun sequence.
ACCESSION   DAEQAF010000110 DAEQAF010000000
VERSION     DAEQAF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11218
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.114"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(69..701)
                     /locus_tag="KRN00_003141"
     CDS             complement(69..701)
                     /locus_tag="KRN00_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH1828988.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(773..1126)
                     /locus_tag="KRN00_003142"
     CDS             complement(773..1126)
                     /locus_tag="KRN00_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1828989.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVDSFGKPQFVYSWK
                     LVSTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLHAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(1204..1407)
                     /locus_tag="KRN00_003143"
     CDS             complement(1204..1407)
                     /locus_tag="KRN00_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1828990.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNGNRIQIKRKQFEKIVDTLDVI"
     gene            complement(1788..2018)
                     /locus_tag="KRN00_003144"
     CDS             complement(1788..2018)
                     /locus_tag="KRN00_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1828991.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DKYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(2020..2427)
                     /locus_tag="KRN00_003145"
     CDS             complement(2020..2427)
                     /locus_tag="KRN00_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1828992.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            complement(2787..3236)
                     /locus_tag="KRN00_003146"
                     /pseudo
     CDS             complement(2787..3236)
                     /locus_tag="KRN00_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(3250..4176)
                     /locus_tag="KRN00_003147"
     CDS             complement(3250..4176)
                     /locus_tag="KRN00_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828993.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            complement(4301..5083)
                     /locus_tag="KRN00_003148"
     CDS             complement(4301..5083)
                     /locus_tag="KRN00_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBH1828994.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDFPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(5239..5859)
                     /locus_tag="KRN00_003149"
     CDS             complement(5239..5859)
                     /locus_tag="KRN00_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1828995.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFFNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(5947..6645)
                     /locus_tag="KRN00_003150"
     CDS             complement(5947..6645)
                     /locus_tag="KRN00_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1828996.1"
                     /translation="MYKLSYVVRVSTKDLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFRATQTLGEHEDIYLGYNLDTGKNVYLK
                     PDLASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKNDSESLAIDILTFLAGISSRDSD
                     KFLQKNDNWKIIME"
     gene            6746..7561
                     /locus_tag="KRN00_003151"
     CDS             6746..7561
                     /locus_tag="KRN00_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBH1828997.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMENDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDYQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNVKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            8233..9000
                     /locus_tag="KRN00_003152"
     CDS             8233..9000
                     /locus_tag="KRN00_003152"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH1828998.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDITKEAKELEDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(9328..10005)
                     /locus_tag="KRN00_003153"
     CDS             complement(9328..10005)
                     /locus_tag="KRN00_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1828999.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(10155..10472)
                     /locus_tag="KRN00_003154"
     CDS             complement(10155..10472)
                     /locus_tag="KRN00_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829000.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(10494..10832)
                     /locus_tag="KRN00_003155"
     CDS             complement(10494..10832)
                     /locus_tag="KRN00_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829001.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT         3750 a         1752 c         1576 g         4140 t
ORIGIN      
        1 caaattttga aaaagctctt ataaaatgat tattaaagta aagtttaata taaataaatt
       61 ataaaatatt aaactaattt atcaatattt cctgattgaa tatgcttaat gtttgattga
      121 atttttttat atggccaatc ccaccattta atttctaata attttgaaat tgtatcatta
      181 ttaaatctct tttttataat ttttgcaggt actcctccaa caatagaata cggtggaacg
      241 tcattagtaa ctactgctct tgttccaata attgcaccat caccaatatt tacacctgac
      301 ataattatag aatcataacc tatccacaca tcatttccaa ttataatgtt acccttattg
      361 tcccaagcgt ccgttatatg gttgatatcg agtttccatt cttcataaaa gatgggaaaa
      421 gtatatgtgg attttgattt cattgagtga tttccactag tcattagaaa ttttgcatta
      481 catgctattg agcaaaactt accaattatt aatttatcat tgtttatagg gtaatgatac
      541 aatacattgt ttttctcaaa atctcttggg tcattataaa agtcattata tattgtgtaa
      601 tctccaactt ctatattttc ccttgttatt acatttttaa gatatacagt ttgataatca
      661 ttacttcttg gatatacctt atttgaactt ggaatagtca tatttaaatc tctcctttaa
      721 tatatattat gtttttgact attccactac tacaatacat ctcttcacag aatcactcct
      781 tgttcagaat cttcataaga taatggcgtc cttttttagt gttaagtcgg atattctttc
      841 ttagtacatt ctttttagcg tgtaactgac aaactgtcat tttcttacca atagtgtcaa
      901 tgctatcatc aaggtcattt tgtattgctt tttccttatc ccttaatgat atatcatcac
      961 gttttccctt tgggggttta tcagtagata caagtttcca agaataaaca aattgtggtt
     1021 taccaaatga atctacatac ttatatgcgt atcttccatc ttttctctgg ctctctccag
     1081 ttcttaaaat tctatcttta ttatctcgtc ttttttcagt tgacatgata agaagctcct
     1141 ctcaataacc gaattgagct tgatacgtca tatgaatatt ataacatata aggctcgatt
     1201 ttattagata acgtcaagtg tatcaacgat tttctcaaat tgttttctct ttatttgaat
     1261 gcgattgcca ttcataatga cccagccaga atcaaggttt tcatcagcaa gtttacgtaa
     1321 ttttttctct ccaatacgaa agtattttga cgcttcttca atcgtcaagg tatatttttc
     1381 ccaaataggt acatcagtat tgttcataga atgtatcact cctttctatg ttcgtagttc
     1441 agaagtagat agatggcttt ggtaagctcc attggtattt caaccaatcc cattcttatg
     1501 ggcaaaaccg tgtcatacag gtgtatcatt atactgtgac ggcaaaacaa ccgttccaaa
     1561 ggttattcac aaatcactat atagtggctc tcttgattaa ggtcatggcg tataatattt
     1621 gttggctatc tgtatcacaa acgtatctat ctactttatt cagttgtcaa agaacagtcg
     1681 gcattgattt gcctataaaa aatcacaata gcttgtgggc ttttatagac aaataattag
     1741 tgattctcca tgtaccaaat agcttgatac atggagagag ggcgagatta agacaaatta
     1801 aatctcaaaa tagcagtgat tagttttgtt cctagcattc gctttgtttc ttcttctaca
     1861 tgaatatagg gatttccgta tttatcaaat aaagttttct gtgaaagacg aatgatatag
     1921 tgttcaaaat gtttaagtat tccgtttatt gcatttacat cgccatgtac agcaagtaaa
     1981 ataattgtaa aaggtaatac ttctttagta ggtttcattt caatgttcct ccatgagttc
     2041 tttcaactct tttagtgcat ttgttttgtg ataatgtatg gtattttctg ctaaatccat
     2101 caatgttgct atgtcagcat ttgtcatgtt gagaaagaat gaaagtagaa ttatatcttg
     2161 ttttcttttt gtaagttttc cgattgcttg cgccattaat acatcttcaa ttcgtatgtt
     2221 gtagtcgtaa gaaaccatac agatgtagtt agaatcataa tcatctaaaa tactcaattt
     2281 acttaattct gcaagtgaca aagattcgag agataccaaa taatcatttc tgcgtttatt
     2341 ttcgtcataa atatctctag catagttacg caaaactgtt ttacagaaac tgtcgaattg
     2401 atgttcaatt gtcttttcat caaccataag atttcaccct ctttccatcg caaggagtta
     2461 aataaccttg cttactccta tcacggtggg agggcgttaa atcttcgata aatttcaaaa
     2521 aaaagagaaa aaaatacaca ctctgcctat agggcaaaaa tgtgtattct ttaaaacgta
     2581 tttaatttat attggttgta agccaccacc atattgatgt atggaaatat gcattggcta
     2641 gcttttcata aaaatacaaa gatgcataag aaattaatag aggggaaaaa cttattctgt
     2701 tattaaaaag taggttaatt ctaataaatg ctattgcggt cgaattaaac tatatacatg
     2761 gcaatcaatc atgtttctat tctttattat gaattgtgac agtattcttc aatcttaaag
     2821 ccacattttt ccaatacttt acttgactct ctattgtagg aatatacatt agcatgaatt
     2881 ttgttaaggt tgtatttttc aaaggcaatt ttgcatattt cttttactgc atttgttgct
     2941 atccctttgc ctcaatagtt cctagcaagc cagtaaccta attcagcatt tttattaata
     3001 gaggtatctt cttcaaatgt taggctgata cttccaatag ccctttcttg ataaaaaata
     3061 gcatagctaa gttgtttaac atctgaagtt gccaaacaaa aactaataaa atctctagcg
     3121 ttttgctccc tataagggtg ggggaagttg tcacgaagat tctttgcaat ttctttatca
     3181 ttcgcaaact caactaaatc ggtaatataa gcataattcc actctataag ttccattttt
     3241 cttctccttt tatgaaacag ctacaagaaa tctttctaag ccaataccac ttatcaaaca
     3301 gcgttctttt ttatttccaa gcatttgata agtccagtca acaaatccac cgtcaactat
     3361 ttcaacggtt tcatttcctt gtttgaccga taatttgaaa ttgatacctt tataataatt
     3421 attatcaaca tcatcattat gaattgataa ctctatatta ggaaaaataa gtttgatagt
     3481 ttcaaccatt ctgtcgaaaa atccgtcatt atctttgtat ccgtttcttt tgcgtagaat
     3541 aatagagaaa cgaacatttt ctatttcact taatatatct ttataatagt ttaagtgctt
     3601 ttctaacaac attttttcac aagtgtaaga ccctgtatct ataccagatg aaaccataca
     3661 atataagcca aaatgtgaat ataaaccttt acctacaaaa ttttgtgctc ttattaccct
     3721 agcagtagta gccatgtgga taggtatggt attattttct tcttttcttt ttaatttatc
     3781 agcaataatt attgccaaca tatttgaggg gtctgcaagt gtttctgtcc ctcgtagagc
     3841 acttactacg ttatattgat ctacggagcc aaaaacgcta cagctaccta atggggcaga
     3901 gggagaaagc ataatcgtct tgatatccat attgaatgct tttctcaata attttgattc
     3961 caaagcatga atttcttctg gatctatacc gctagggata gtaaatctat ttagttggta
     4021 tgactttaga atatcagttg cagttaaagt atttgcttgt ctatcaaaca cttctaatag
     4081 aagtgagttc aaatctgatt ttgatagagc tgataactta tcaactatat tcttatcccc
     4141 aattttattt gtaattctac ttaaaatatc actcatagtt atcctccata ctgttacttt
     4201 caaaataatt atagaattgt tacaacaact aatctaggtc atttgaccaa aaatgaaaaa
     4261 acactgaata tttactattc aatatttttt tactttgggt ttatttgatt aaatcttgaa
     4321 aatactgtaa tgcaaccctt tcagcttcaa cctttcggac aataggactt tgtgataatt
     4381 cctctcttaa ctcaagatac aggttgatag tagcctgcaa tgcattaaca cagcttttat
     4441 attcatggtt agcaaccgtc ttttctaatg cttcaatata ttggggtgcg tccaattcaa
     4501 tttttctaac tccacgaggt aatttaccta agagaagctg tattaatggg gcaagtactg
     4561 attgtcttaa aaaagataaa aaatcaattg tttcaaatag ttctctacgt ccaatcttag
     4621 tgcaagcgta atgaacccaa atccaaaatc tatcttcaat ccactgtaag tctggagttg
     4681 ggaagtatgc ttctttttta gaataaattt ctgttatgca gttgttttct tcatagagaa
     4741 tagctgaatc ttcaacccta tctagtaaac catctaaggt tgtaaactta aaatcaacat
     4801 gaagaacagg gaaatcatag agggaaatta tcaatcgagg ttctccaacg tgttcgccag
     4861 taaaagcaga aactaatgtt ccaaactgtt ccacaataag taatctctct tcgataactt
     4921 cttcatagga tttatcatct gctacaatca gaaaatccaa atcagaatat tcatctaacg
     4981 attttgtgat ataagaaccg ctaattgcaa gtcctattat cctactatct ctttttgaaa
     5041 attctaatac gttttgtatc atttcctgtt gtgttttagt cataatataa cacctctcac
     5101 tgtcttttat tagctatcaa tccaacataa ttatgcatag gagtattata taatgaagaa
     5161 ataaaaaaaa ataggtcact tgacccgaaa taaaaaagta ttgaataatt attatccaat
     5221 acttttttga aattatactt atgttgtagg aagattcttt aatacctctc gctgattaat
     5281 tacactaaat cttttgtttt cataagcaat tagatgttct tgtacacatt catttatagc
     5341 acgattaatg cttctaattg gagcgtttac ttcgctagca agctgttttt tggtaagcag
     5401 atttaattca cttctataat agtgtaagga tatacacctc agaagtcgtt ctttaacact
     5461 taaagatgat aattcttcaa ttaattcagc atttacaact aatttactag atatttctcg
     5521 aatcagaaat tttgtagctt caaaatctcc ccttaaccag ttaaaaaaat catctctatg
     5581 aagtttatat acattacaat ctgtgaaagc gacaatttca acgggttttt tcccatcatt
     5641 aaattgttcc atttctccaa aaaaactacc acttctataa agatgaatag ttgagatgtt
     5701 tcctttcaca tttaagatga atgcttctgc aataccgtca atcataagaa ttacatattc
     5761 attttcttgc tcagcaaaaa gaatagtctc tttcttttta tacgtttttt taacaagctt
     5821 ctttttaata tcttcattca taaaatcaat taaatgcata ttcatccctc cttaccaaat
     5881 ctttgattaa attatatcat ctttcaatta gttaggtaag atagtaaaaa tatatttaca
     5941 tagaaactat tccattatta ttttccagtt gtcatttttc tgcaaaaact tatcactgtc
     6001 acgactggag ataccagcaa ggaatgttag gatatcaatc gctaaacttt cagaatcatt
     6061 tttacggctc aaaatgacgt aagggtcaag caatcctttg ttttcatcat tactggttaa
     6121 attgacaatg tttatctcat gggctatttc tggtagcgtt tctttccatt tgccgcgttc
     6181 tgctttaggg tcaactatga ccgcctgtcc gccgaatagt accgcatagt aaacaagcat
     6241 attgttactg aataatttac caccacccaa tgaaccgata aacgcagacg ctaacgcatt
     6301 ggtaatagaa ccctttaccc cttgactagc aaggtcaggt tttagataga cattctttcc
     6361 agtgtccaga ttgtagccaa gatagatatc ctcatgttcg ccaagggttt gtgtcgctct
     6421 aaaaccaagt ccagccaaaa aatccgaagt gacatattga atataatcat tgatgtaacg
     6481 tttgctgaca ggaataaatt cgccatgcaa tcctaacata tccccaaagg gacgcacgag
     6541 cttgattgat aagtcgtcgt aaaagtcttt gacttcatca caacgccttt ttagctcgtc
     6601 aagatccttt gtagatacac ggacaacata gctaagttta tacatagatt ctttacagtt
     6661 aaaagtctgt ttttaaaaaa atgtataaat tataaatcaa aatatagata ctatcaatga
     6721 cccactaggt gcaaaaagca ttgatatggt taaattatca gacgctaaaa gctgggctat
     6781 ccgaatgagt gaagatgggt gcgcttataa atccattgac aattataagc gctcactgaa
     6841 agcgtcgttt ttcatggcaa ttcaagacga ctgtattaga aagaatccat ttaattttca
     6901 gttaagtgat gttttggaag atacaacaga accaaaaatc gctctaacac cagaacagga
     6961 aatgggctta ttatccttta tggagaacga taagacttat tgtaaatatt atgatgatgt
     7021 tgttatcctc ttagaaacag gactacgcat ttctgaatta tgcggtttga ctttagaatt
     7081 ggatatgaaa aataaagcca ttatggtaga ctatcaattg ttgagtgata ctaagattgg
     7141 ctattatgta gaagttccaa agaccacaca gggtaagcga gaaattccaa tgactgaaag
     7201 agcttatcaa tcatttgaac gtatcgtgga acggcgtaag aacgttaaag cagaaccaat
     7261 cattgttgat ggttaccaga acttcctatt tcttaaacaa gatggattac caaaacaagc
     7321 aactcattat caaagcatgt taagagcgtt agtcaagaag tataacaaga cccatgagga
     7381 caagctacca aagattacgc cacatacctt taggcataca ctctgtacaa atatggctaa
     7441 caaaggaatg agtcctaata tattgcaata tattatgggg cataaaaaca ttactatgac
     7501 gcttggctat tatgcacatg gttcatttag ttcttcgaga gctgaaatgg aacggttata
     7561 atcctagtag tatgactaga gtttactact tatttactac ttttgatggc attcttatac
     7621 agttaaatgc caacttatgc aaagtatctt ccaaaaagaa aatgccgata ctccttgtag
     7681 atacaggata tatcgacatt taccaactta tgaaaagata atcaaattta atataagttt
     7741 ttcaaataaa aagatactaa attctttttc gagaatctat ataacattac ttaagcttgg
     7801 ttggggcata aacaattgag tagctacttt tgtatggtgt tcaactttag tcaaaactct
     7861 taagcaatgc aaatgattta gattcattaa tattcaatct cttcataagt agtgaaattc
     7921 gagttatttc tgcataatta tactatgatt tatagattaa ttctattagc atccagaata
     7981 atattgttta tatgaataaa atttaaagaa tattgtgaaa attatagaat gttaaaataa
     8041 atttaggtaa aaaagaagtg tttgtatatt atagagtacc ttttctaaaa tatgtgggat
     8101 tgttttaaga attagaataa aaattatttt taaattagta tttttataat gtatagtatt
     8161 tttaatgtat aattaaattg tgcagaaaat agaatttaaa gtcctataaa atttctgatt
     8221 atggaggaga atatgaaaag aaaagttcaa gtaaaaaata ttactattgg agaaggtaga
     8281 cctaaaattt gtgtaccaat tattgggaaa aataaaaaag atattacaaa agaggctaaa
     8341 gagttagaag atgcatgttt ggatattata gagtggcgag ttgatttttt tgagaatgta
     8401 gaaaatatta aagaagttaa ggaagttctc tatgaattaa gaagttatat acatgatatc
     8461 cctttattat tcacatttag aagtgtagta gaagggggag aaaaattaat atcaagagat
     8521 tattatacta ctttgaataa agaaatttct aatacaggtt tagtagattt aatagatgta
     8581 gagttattta tgggagatga ggtcatagat gaagtagtta attttgctca taaaaaagaa
     8641 gtgaaagtaa ttatatctaa tcatgatttt aataaaactc caaaaaaaga agagattgta
     8701 tctcgtttat gtagaatgca ggaattgggc gcagatttac ccaaaatagc tgttatgccg
     8761 caaaatgaaa aagatgtgtt agtgctactt gaagctacaa atgaaatgtt taaaatttat
     8821 gcagatagac caataataac aatgtcaatg tcaggaatgg gtgttataag tagactgtgt
     8881 ggtgaaatat ttggttctgc attgactttt ggagctgcaa aaagtgtttc agcaccaggg
     8941 caaatatcat ttaaagagtt aaattcagta cttaatctat tacataagag tattaattaa
     9001 attaattata tagaaatatt agatgatatt tttgaatata taaattaaat ataaaaaact
     9061 tttcagatag taaaatttaa attgggcaat tatatctgaa aagcaactat ttagtgtgta
     9121 ttttgaaagt gatatagaaa atcttataaa tcaactatgg catatttaaa atatgccatt
     9181 aaaacctact agacattaga ttatagatgg tatactagca tttctattat ttatagatag
     9241 taagttttca taataactgt tttatctaaa gtagaagata tatttgtatt atgtatattt
     9301 gtcattattt ttttgtaatt atgtatatta atggttatat atgtaatata atattatcac
     9361 tctatttttt gtatattgta cattacaaca tttatatcta tcatcatcaa ttacagtaga
     9421 atgtatggga tacttatttt cacttaacca atatttttgc atattctttg tccaagactt
     9481 tggaaacttc aatacttttt tgtttattat aacatcctca tcttcaaaaa tattaacttc
     9541 tctttctatt tttatttttc tgttgtatat cttattgata gattctttgt cgagttttat
     9601 gtctctatac atatcagggc aatagcaaca aacataattt cttttttttc gacgtttaaa
     9661 tttcacaact ttctctatgc taatttctaa tttttttgta ccatctttta taaatttaat
     9721 atcttctatg ttctcgcttg aaaaaatttc tgtcaatctt aaagtatcta cagtttctct
     9781 aattatttgc tttttataag aagagaatcc atatccaaaa gaaaggttta atttattagg
     9841 gatgtagcca tttttatatt taaacatctt aattttttct aattcagcat tatctttaaa
     9901 tttcaacttt tcatacctaa aagttacttt gctaaaaaga gtatattcta catcaatata
     9961 ttcttttgca atcttaaatt tatcgctacc ttcaatcaca atcatagcct atctccaatc
    10021 gttttatatt aaaataaggc catagaacat ggtctaatag tactcattag cactataaga
    10081 caatgttaac acaaaaagac aaaaaaaggt tatttatttc aaataacctt tttttttata
    10141 taaaatataa agaattatat tttattcttt tttatgatgt ctataatctg cgatatcaga
    10201 tttagttctc ttgaatttaa gtcttttaac tcttcattta tatcattttc taaatatgtt
    10261 tttccagtgg aagtaatatc ttttataaga acatctgcag aaatatttaa tatatttaca
    10321 aattttatga atgttttaag acttggattc tttttaccac tttcgatttg agttatatac
    10381 caaggcgata ctccaaccat atttgcaaat tcttttgaag ttaaatttgc ttttttccgt
    10441 tcttctttaa gtcttttacc tatataattc attattgtta ctatttccct cacttatatt
    10501 tctttgtatt taatgatgca ctttattaac tctagcattg caatttgttc tttttcagtt
    10561 aatttattaa tcatttcata acattctaaa ggtacagagt tatcaacgcc ttctgttgta
    10621 ataatatttg caaataacaa ttcaagtggt atgtctaaag cagtagcaat tttcattata
    10681 atattgatag atgtatttgt ctcagctctt tcaatctgac caatatatgt tggatgtaaa
    10741 cctgcctttt ctgctagaaa ctcttgacta tatcccaatt ttgttctata gacttttatt
    10801 ctatctccta ttatttttcc tatatttgcc aattattatc cctccacttt agattatatt
    10861 catagtttaa gttgttttat atagactatt tatacttttt tagtctaaat atagactata
    10921 tatgttttta tactgaaata agtgctattt atttttgtat agtctgtatc tacaataaac
    10981 aaatatggat aaatcatatt tttaattaga gaaatatttt cataatttca tagccatact
    11041 acaataataa aacgaattaa taatatgtta attatagcat tttttattgt aattacatat
    11101 tagatatgta gaatatattt tgaaaattaa aaaaattttc tattttatat attgaacaat
    11161 ttatgtaaat agaaaatttt tcaataagac ttttgagttt aatcattata ttggtaag
//
LOCUS       DAEQAF010000111        10984 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.115, whole genome shotgun sequence.
ACCESSION   DAEQAF010000111 DAEQAF010000000
VERSION     DAEQAF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10984
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.115"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            198..1259
                     /locus_tag="KRN00_003156"
     CDS             198..1259
                     /locus_tag="KRN00_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBH1829002.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLIVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            1350..2963
                     /locus_tag="KRN00_003157"
     CDS             1350..2963
                     /locus_tag="KRN00_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1829003.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            3294..5648
                     /locus_tag="KRN00_003158"
     CDS             3294..5648
                     /locus_tag="KRN00_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1829004.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMYAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDKLDTTSNKVNYISDELD
                     TTSNKVNCVSDELDMTSNKVNYVSDELDMTSNKVNYVLDELDITSNKVNYVSDELDMT
                     SNKVNYVSDELDITSNKTDYISNELYNLSNKSIKGNIPIKMAVITKSNMLNQLPDLVE
                     LERVFSKIEFKVCFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVK
                     PAHKLMDEYYFFMELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFT
                     IHNPVAWEDKKFETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNH
                     HADTLFSQHFMDKKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGN
                     YIVKMYVGWWKKHGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            5736..6071
                     /gene="spoIIAA"
                     /locus_tag="KRN00_003159"
     CDS             5736..6071
                     /gene="spoIIAA"
                     /locus_tag="KRN00_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBH1829005.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            6085..6513
                     /locus_tag="KRN00_003160"
     CDS             6085..6513
                     /locus_tag="KRN00_003160"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBH1829006.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            6536..7300
                     /gene="sigF"
                     /locus_tag="KRN00_003161"
     CDS             6536..7300
                     /gene="sigF"
                     /locus_tag="KRN00_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBH1829007.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAVKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            7580..8017
                     /gene="spoVAC"
                     /locus_tag="KRN00_003162"
     CDS             7580..8017
                     /gene="spoVAC"
                     /locus_tag="KRN00_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBH1829008.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            8184..9197
                     /gene="spoVAD"
                     /locus_tag="KRN00_003163"
     CDS             8184..9197
                     /gene="spoVAD"
                     /locus_tag="KRN00_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBH1829009.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            9211..9573
                     /gene="spoVAE"
                     /locus_tag="KRN00_003164"
     CDS             9211..9573
                     /gene="spoVAE"
                     /locus_tag="KRN00_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBH1829010.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            9756..10772
                     /locus_tag="KRN00_003165"
     CDS             9756..10772
                     /locus_tag="KRN00_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBH1829011.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
BASE COUNT         4423 a         1129 c         1987 g         3445 t
ORIGIN      
        1 tttctaatat aataatagca tattattcgt atcctgtata cataaaaaat aaaaaattgt
       61 cgctttaaag tataaaacag attatatgtt aataatgtgg tgaaattata cccatatata
      121 aataaaataa aacaaataaa tagctaatta aggagaaaat attttttatt ttttgtttag
      181 gataaataaa ttttattatg gaaaaaagaa aaagcataca tcttcacaaa ctgaatattt
      241 atttaatagg gggaggtgat agattgttta tcacagtggt attattttta gtaggtttcc
      301 tattaattac taaaggcgca gatatcttta taaattgtac tgtagagata ggtaaaaaaa
      361 cgaatatatc agaaattata cttggagcta ctatagttag ttttgcaaca acattacctg
      421 agtttacagt gtctctactt gcttctattg atggtcatac tactatgagt ttaggaaatg
      481 cagttggttc tataatatgt aatacagggt tagcattagg gttggttgtt tttataagtc
      541 catttaatgt agataaaaaa atgttttttt ctaagtcttt actattaata gtatccgtta
      601 tagttttaat tttattgagt ttagatggag ttataacaag aggtgattca ttattactta
      661 taataatatt aatcttttat atggttaata attatagaag tgtcgttgga aaatctgata
      721 ctaaaaatag aaatattaaa aataacacta ttaaagacat atctactaaa aaagggaaaa
      781 attatagagg tttttccgta ttagaaattg taaaaatact attacttttt gctacaggat
      841 tgataatgat gataataggt tcacaaatcc ttatagagag tggagtaata atagctagtt
      901 ttttaaatat acctcaaggt atagtaagtt taactataat agcacttgga acttctctgc
      961 cagagatagt ttcgtcgatt actgctataa gaaaaaatca tcatgaaata tcagtaggaa
     1021 atattttggg tgcaaacata ttgaatatag tatcagtaat agctgtatca gcaataccaa
     1081 ataacatacc aatactatct caaaatagac aattggatat accattcatg atattattat
     1141 tattaatagt aataatacca acacttaaat ctaataaact tagtagaata caaggtatat
     1201 tgatgttatt cacatatttt ctgtacatat caattttgta tttcatgtat attatttaac
     1261 tatactgttt aaaatattaa ttgcagaata tcctaaaaaa gtatataatg gataggttaa
     1321 gattaattga taacggagag gaataatata tgaatataac aaagtttgaa gatttaccaa
     1381 taagtgaggg aataaaaaaa gctatagctg aaatggggtt tgaagaacca tctcctatac
     1441 aagcacagtc tatacctgcg attttgtcag gtaaagacgt tataggacaa gctcaaactg
     1501 gtacgggaaa aacagctgct tttagtatcc ctatactaga aacaatagac ccaaataata
     1561 gaagtttaca agctgtagtg ctttgtccaa caagagaact ggcaatacaa gtatcaacag
     1621 aaataagaaa gttagctaag tattcgcacg gaataaagac attacctata tatggtggtc
     1681 agccaataga tagacaaata aaatctctaa agagtggtgt gcaagttgta ataggtacac
     1741 caggacgtac aatagaccat atcaatcgta aaacattaaa gatggataat gtaaaaatga
     1801 ttatattaga tgaagcagat gaaatgctag atatgggatt tagagaagat atagaaatga
     1861 ttttaagtaa gattccagaa gaaagacaaa caactttctt ttcagctact atgccaagag
     1921 gaattttgga attaactaag agatatcaaa aagacccaga gcatataaaa gttgttagaa
     1981 aagaacttac agtttcaaat acaaagcaat actatataga aactaggtca tcaaataaat
     2041 tagaagtatt atgtagatta gtagatgtat atgaccctaa actatctgtt gttttctgta
     2101 atactaagag aaaagcagac gaattggtag gagatttaca agcaagagga tattttgcag
     2161 atgcattaca tggtgactta aaacagactc aaagagatat agtaatggat aagtttagaa
     2221 atggtacaat agatatactt gttgctactg atgttgcagc tagaggtata gatgttgatg
     2281 atgttgaatg tgtattcaac tatgacttac cacaagatga agagtattac gttcatagaa
     2341 ttggtagaac tggtcgtgct ggtagagaag gtatgtcatt tacttttgta tttggaaaag
     2401 aaatgagaaa gatgaaagat atagaaagat atactaaatc taaactaata aagcataata
     2461 taccaacaat aactgatgtt gaagagaaaa aagtaggtac tttctttgca caagttaaac
     2521 aaactataga agaaggtcac ttaactaaac aattacaatg gttagaaggt ttctgtaatg
     2581 atgaagatta tgcaatggtt gatatagctg ctgcacttgt aaaactatct ctaggtgaag
     2641 aaatgaaaga agaaataata gaagaaaaac ctagaagaga gcgtggagat agaaaaggtg
     2701 gtactggagc taaagatggt atgattagat tatttatcaa tattggtaga aatcaaagag
     2761 tacaagcaaa agatatagtt ggtgctatag ctggagaagt tggaatacca ggtaaagtag
     2821 taggtactat agatatatat gataagtata cttttgttga aatacctaaa aaagatgcaa
     2881 aaacagtaat tgaaaagatg aaagatatta agataaaagg taataagatt aatatagaaa
     2941 aagcaaataa gaagaaaaaa taacgtatag tatacaaaac tataattaga aaatatataa
     3001 aataatatat tggatattta aaaagcctga tgtgttttca aaacagatag tagataatct
     3061 gtaagagtta acagcataag gcttttcttg ttttatataa ggaatctgaa taacttactg
     3121 ttaaatcttt gaattactgc acctcattta cgttaaggat ggagtattct acctattttt
     3181 gataaaatat atctatgttt tatatactgt agttttgaat atataaagtt taataaatta
     3241 tagtatatat gttaattttt aataaggtaa gaaagtagaa agaaggatat tttatggata
     3301 taataaaaaa attaagtcat gggtgtacat tagattgtca tgactgttgt aaattcaatg
     3361 tttatactaa aggaaataat gtagtaaaaa ttgaaggaga taaaaatcat ccttatacaa
     3421 aaggttttat atgcaaaaaa gggatggccc atttagatag attaaatcat aaagatagaa
     3481 taaagactcc tatgcttaaa gttgatggag tatggaaaga gatttctttt gataaagcta
     3541 tagaaataat ggcagaaaag cttacatact ataaagaaaa gtatacatca aagtctgtca
     3601 tgcattatga ccaatatgga agtgggtctg tgctaaaata cataggagat atatttttta
     3661 atttttatgg aggtgttagc agacataagg ggggtccctg ttggagtgca gggatgtatg
     3721 ctcaaaaata tgattttgga gtagctaaga gtcatgctat agaagatatg ttaaatagta
     3781 aaagtatatt tgtttgggga aaaaatccag catatactac aattcatact atgcaaataa
     3841 ttaaaaaagc taaagaaaaa gggataaaga tagtagtgat tgaccccata tatacaaaaa
     3901 cagctcaaat agcagataag tatgtacaag taaatcctgg aacagatgga gctttagcta
     3961 tagctatggc aaaaattata gtagaagata aattatatga tgaagaatat ataaactcgt
     4021 atgttattgg ttttgaagaa tataaaaaat atttatcttc attggaatta agttttttaa
     4081 ttgatgaatg tggtgttaaa gagaatgata taagagagtt agtggattta tatactaaca
     4141 aatattcaag tataaatgtt ggatatgggc ttcaaaaata taaaaatggt ggaaacacaa
     4201 taagagcaat agatgcttta ggtgctataa ctggtcaaat aggatttagt ggtggagggg
     4261 taaactatgc taataaagtt tatccgagtg ttataaattc tgacccttac aatagccaat
     4321 catatggtga agatagggag ttttatgtaa gtaatatcag taaatttata gaagaatctt
     4381 taaaaaatac atcaaataaa gtaaattatg catcagataa acttgataca acatcaaata
     4441 aagtaaatta catatcagat gaacttgata caacatcaaa taaagtaaat tgtgtatcag
     4501 atgaacttga tatgacatca aataaagtaa attatgtatc agatgaactt gatatgacat
     4561 caaataaagt aaattatgta ttagatgaac ttgatataac atcaaataaa gtaaattatg
     4621 tatcagatga acttgatatg acatcaaata aagtaaatta tgtatcagat gaacttgata
     4681 taacatcaaa taaaacagat tatatatcaa atgaattgta taatttatct aataagtcaa
     4741 tcaaaggtaa tattcctata aagatggctg taataactaa aagtaatatg ctgaatcaac
     4801 tgccagattt agtagaattg gagagggtgt tttcaaaaat tgaatttaaa gtatgttttg
     4861 atatgtttat aacggataca gctactttat gtgacatgtt tataccgtgt acaaatacac
     4921 tggagagtga agatataatt tatagctcaa tgaccaatcc atatataacc tataatgaaa
     4981 gagctgtaaa gccagcacat aaattgatgg atgaatatta cttctttatg gagctagcta
     5041 aaaagatggg attaaatgat tatccttttg tagaaaagag aacttattta gaaaaagtga
     5101 ttgaaccact taagcgtttt gacaaaaatc tggatataga aaaacttaaa aacaattact
     5161 ttactataca taaccctgtt gcttgggaag ataagaagtt tgagactcca tctggaaaat
     5221 acgagcttta ttcagaaagt ataaaaaact tgggaataag tccaacacct gtatatataa
     5281 gcaataaata taaagaaata gaagataaaa atatttcttt tagattatta actaatcatc
     5341 atgcagatac tttatttagt cagcatttta tggacaaaaa atctatagct caagcatata
     5401 taaatcggag aatggctaaa aaagtaggta ttgaggacaa agatattgtg atattgaggt
     5461 caaaaaaagc aaaaataaat gtacaaataa atatagatga tggagtaggt aattatatag
     5521 taaaaatgta tgttggttgg tggaagaaac atggaaatcc taatagttta acagacactg
     5581 gtatatcaga ttttgggggt caggtaacat ataatgaaag tatggtagaa ataatacgac
     5641 aaaactagtt aaatttcatt gaaggaataa aaatataatt atagaattga ttaaaagtta
     5701 ctatttttac aaaactattg aaggagggat ttttgatggt aaattattcc ttagaacata
     5761 agaatctata catagaattt atgtgctcag aactagacca ccatgtagcc aatgaaataa
     5821 gggaagaaat agataactta ttaagtgtaa atcaagtaaa aaatgttgta tttaattttg
     5881 aaaatattaa ttttatggat tcttcaggta taggcgtcat cataggtaga tataaaaaga
     5941 tttctaatga agggggacga gtttcagtaa ttaatataag ttcacgagtt aagaagattt
     6001 ttgatttatc tgggttaaat aaaattattg gcatttatga tacgtatgaa gaagctctaa
     6061 gttctttgta gggaggagta tgtgatgaat aatattatgg aagttaaatt ttcggcaata
     6121 tctgaaaatg aaagtttagc aagagttata gtagcatcct ttgcagctaa gttagaccca
     6181 acagtagatg agttagtaga tataaaaact gctgtctctg aggctgttac gaatgctata
     6241 atacatggat atgaagaaga cagttctaag tttgttttct taagatgtga gatagaagga
     6301 aatactataa agattatagt tgaagatgaa gggtatggaa tagaaaatgt ggagaaggca
     6361 atggaaccac tttatacatc aaaaccagaa cttgatagat caggaatggg attcacagta
     6421 atgaaaagct ttatggacga tgtagaggta agttctgtaa aagataatgg gactagaatt
     6481 gaaatgacta aaaaaataaa tgtgcctaaa taaagtccaa aagtgaggtt ttattatgga
     6541 agtaactgtt gccagagaag aaaaaaaacc tcttcttagt catgaagaga ctctagaact
     6601 tattgaaaaa gttcaaaatg gagatgaaga ggcaaaagaa atattaatat caagcaattt
     6661 aggtctagtt aggagcgttg tatctagatt tttaaatata ggatatgata gagaagattt
     6721 atttcagtta ggttctatag gcttaataaa atcaatatat aaatttgacc caaaatttaa
     6781 tgtaaaattc tctacttatg cagtaccaat gattttaggt gaaataaaga gatacttaag
     6841 agatgatggt atgataaaag tatcaaggtc gttaaagcaa atagctgtaa aggcaaagat
     6901 ggaaagtgaa gctttaacta aaaaattagg tagagagccg agtatagaag aattagctaa
     6961 agcaatagat gtagaaaaag aagatttagt aatggctatg gaagctaatt tcaatgttga
     7021 gtatttgcaa ggagttattc atgaagagga aggttctcca atatgcctta ttgataaaat
     7081 aagcatgaaa ggagaaagtg aagaagaaaa agtagtggat aacatattgt taaaagacat
     7141 acttggaaga ctggataaga gagagcgtca aataatagtt ctcagatact ttgaagacat
     7201 gactcaaagt gaaataggag agatgctcaa tatatcacaa gttcaagtat ctaggataga
     7261 gaagaaagta ttgtctaagt taaaagaata tatatcgtga taatacttat gatatgtaga
     7321 ataataaaat ataataaata tattactaaa ataaaatgta ataacttttt atgttaagtt
     7381 tttaaattat taaaagatat taaaataata aaaagcatta aaaaagtaaa aatataaaaa
     7441 caaggtgtct ttatggaaaa atagattttt tctttattag gcatcttttt tattttttga
     7501 taaaacttta gatagtcaaa ataaataata ggtttatttt tttaaaatta acaaataata
     7561 ctttagagag gtgtttagta tggataaaaa ttataaaaaa tatgtagacc aaataagccc
     7621 aaaacctaca tatttaaaaa actatacact tgcatttatt gtaggtggaa ttatttgtat
     7681 gatagggcaa gcaataaatg atttgtatat gaaagtggga ggtcttgata aactaggtgc
     7741 tagttctgca acatcaataa cattaatatt tataggggca tttttaactg gattaggagt
     7801 ctacgaccta ataggaaaaa gagctggagc tggttctata attccaataa caggttttgc
     7861 taactcaata gtatctccag caatggagta taaaagagaa ggctatgtat taggtgtagg
     7921 tgcaaactta tttaaaattg caggaccagt tttagtttat gggataggtt cttctatttt
     7981 atgtggaatt atttattata tttttaagat gttttagatg atttttattt aatttaaatt
     8041 ttattaatta tgaagaaggt ataaaatctg aaaatagcta ctaaagtaac taattgaaaa
     8101 ataattgtgc agatttaatt aatattttta attaatatta aaaatttgaa tagtaaaatg
     8161 caaaattaaa aaggtgtgaa aatatgaaaa ataaaagaat tggaaaaaga acagtcaagt
     8221 tagaaaataa accaaccata atatcaactg gaactatagt aggtcctaag gaaggtgaag
     8281 gaccactaaa ggactatttt gatatgatta tgactgacga tttatatggt gaaaagactt
     8341 gggaattagc tgaaagtaaa atggtagaga ctgcatctca acaagctatc caaaaggcag
     8401 gtaaaaaatt gtcagatgta aattatatgc taggtggcga tttaataaat caaatagttc
     8461 cagcatcctt tgcagcaaga gaactggcta ttccattttt aggtatatat ggagcttgtt
     8521 ctacaatggc agaaggtctt tgtataggtt ctatgcttat agatggtggt tttgctgatt
     8581 tagtactgtc aggtacatca agtcactatt gtacagcaga aagacaattt agattcccac
     8641 ttgaacttgg aaatcaaaaa ccaatgacag ctcagtggac agttacagga gcaggaagtg
     8701 tattattagc tcctaatgga gacggtccaa aagtaaagta tgttactgtt ggtaaagtaa
     8761 tagatgaggg tattgatgat ggtaataata tgggaccagc tatggctcca gcagcaatag
     8821 atactatcta ctcttacttt gaagatacta atgatgaccc aaatagcttt gatataattg
     8881 ctactggaga tttaggtact cttggaaaac agatagcaga agactttcta aaagaaaagg
     8941 gtgtagatat atcaaaagtt tatactgact gtggtataga gatgtttaac cttaaagaac
     9001 aagatgtcca ctgtggtgga agtggatgtg ggtgttcagc tacagtgttt gcaggatata
     9061 tatatgataa gttgagaaaa aaagaattta acaaagtaat gcttgtatca acaggagcac
     9121 tactttcacc gacaagtaca ctacaaaagc agacaatacc atgtgttgca catgcagtag
     9181 taatagtaaa tgagtaggaa gtgatataat atgttaatgg actatgtaag agtatttatt
     9241 gtaggtggaa ttatatgttt aatagcccaa gtaatgatgg attatttcaa aatgcaaact
     9301 ccatatgtta tggtaacgta tgtaacaact ggtgtagttt taacttttct aggtctttac
     9361 gagccattag ttaagtttgc agcagcaggt gcaacagttc ctataatagg atttggatat
     9421 tcacttgcta caggagtaat aaaatcaatt caaagtgatg gttttttagg tattttttta
     9481 ggaggtacaa ctgctacagc tggtggaata gcagcagcta tattctttgg atatattatg
     9541 tcagtagtat ttactccaaa agcaaaacca taaatcttta ttaaaagaat aataagtttt
     9601 tgaaataata aatttttata aagcaggtgg atatctttta gattccacct attttttata
     9661 taaagaagcg tttacataat tgaagttgac aattatttac aacatagtgt agtattatat
     9721 tatcaaaata aaatgaagtg aagtagggga taaagatggt aactattaaa gatattgcaa
     9781 ggaatctagg tatcagttat tcaactgttt ctaggtgctt aaacaataat cctaatgtat
     9841 ctgaaaaaac aaaaaagaaa gtggtagaag aggcaaatag actagggttc cattttaatg
     9901 taaatgcaag aaatttagca aaaaaagaaa ctaacaggat aggggtaatc ttttcaaata
     9961 attttaatca tcaagatact agaaagtttt ttagtgatat aatggatagt tctataaatt
    10021 ctattgagac taataaatac gattttataa tacagcctaa taataacatt agtggtgata
    10081 gtaatgtata taaaatggta aatggacaaa tggttgacgg attagtaatt gtgtctcaat
    10141 caataaaaaa agaagagtat gattttttaa aagacaataa ttttccacat gtatttatat
    10201 attttaaacc atcttttata ggagaagtag ataatttctt ttgggacgat aacgtgtatg
    10261 gaggttatat agctaccaag catttaattg accatggtca taaagatata ataacagtaa
    10321 cttcagatga taagagttca aaaatgcatg aagatagaac caagggatat ttgaatgcta
    10381 tggaagaagc aaatttaaag acagaagtca ttaaatctaa aatggatttt gaatctcaag
    10441 ttgaattttt agaaaaatac attgataaaa taaaaaaagc ttcagctata tttgtacaac
    10501 aagatgtacc agcgatttct ataatacaag agttaaaaac tacttatggt ataaatgtac
    10561 cagaagatat ttccataata gggtataata atattgaatt aatatcatat tttaggtcgc
    10621 atttatcaac aatagatgac ccaagagagc aagttataaa aaatggagta gatagtttag
    10681 taaatataat aaataaaaag agtacagaac acattccaag aaaattatat ccaaggttaa
    10741 taatacgaaa tagcgttaaa agaataaagt agtaagcttt taagtatcaa acgtttatta
    10801 aaaatattat agattatgtg aagtttttta acaaataata taaataaaaa ttaaaaggag
    10861 taggtgtata taagtacatt gtactccttt atttattgag atagttttta taatatgaat
    10921 gaataatttt attcaattat ttgaaaatcc gttattttaa caatataaat taataaatta
    10981 tttg
//
LOCUS       DAEQAF010000112        10734 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.116, whole genome shotgun sequence.
ACCESSION   DAEQAF010000112 DAEQAF010000000
VERSION     DAEQAF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10734
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.116"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            285..743
                     /locus_tag="KRN00_003166"
     CDS             285..743
                     /locus_tag="KRN00_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBH1829012.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMGIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            804..1079
                     /locus_tag="KRN00_003167"
     CDS             804..1079
                     /locus_tag="KRN00_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1829013.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            1138..2412
                     /locus_tag="KRN00_003168"
     CDS             1138..2412
                     /locus_tag="KRN00_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBH1829014.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            2542..3594
                     /locus_tag="KRN00_003169"
     CDS             2542..3594
                     /locus_tag="KRN00_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBH1829015.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DNHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDINPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            3594..4625
                     /locus_tag="KRN00_003170"
     CDS             3594..4625
                     /locus_tag="KRN00_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBH1829016.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGATVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     KESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            4717..5529
                     /locus_tag="KRN00_003171"
     CDS             4717..5529
                     /locus_tag="KRN00_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBH1829017.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            5532..6452
                     /locus_tag="KRN00_003172"
     CDS             5532..6452
                     /locus_tag="KRN00_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBH1829018.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            6627..7073
                     /gene="rpiB"
                     /locus_tag="KRN00_003173"
     CDS             6627..7073
                     /gene="rpiB"
                     /locus_tag="KRN00_003173"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBH1829019.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            7103..7768
                     /locus_tag="KRN00_003174"
     CDS             7103..7768
                     /locus_tag="KRN00_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBH1829020.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            7878..9380
                     /locus_tag="KRN00_003175"
     CDS             7878..9380
                     /locus_tag="KRN00_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBH1829021.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(9692..>10734)
                     /locus_tag="KRN00_003176"
     CDS             complement(9692..>10734)
                     /locus_tag="KRN00_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1829022.1"
                     /translation="SMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFMYIYYAEAIA
                     IVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVIGDDEISTLA
                     KSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDMLKNNDFDRET
                     INDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQSIVEFEDKIQ
                     NSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDMFIKEENIIL
                     TFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENAHMEIIIDAD
                     LFKVMLTFRRVN"
BASE COUNT         4290 a         1218 c         1962 g         3264 t
ORIGIN      
        1 taaaaaacca tttgtaaaaa acaaaaaaat catttctcta acaaaaaaaa ccacaaaaaa
       61 tataaaaaag tatggctagt taagtgatta acaagtaaaa attaaaataa aaatcaaaaa
      121 aaatttatca atgaaagtca gctaaaatcc tggaagagag cattattttt gggaaaacat
      181 tttcttttgt ttcacaaaaa aagccacttt ttggcacaca acatgcttta tataaagtca
      241 agaaaaacta aggtataaga caaaggcaat taggaggtgt aaatatggag tttataaatt
      301 ttgtaagtga taaagttata gaccttaaaa tggattgtaa aacgaaagaa gatttcttta
      361 aagaaataca taataaagtt tttgatttag gctttgtaaa agaagaattt ggagaaaaaa
      421 tattagcaag agaaaatgta tttccaacag gtttaaattt aggagattat ggagtagcaa
      481 taccacatac agatgcagaa tatattaaag agcaatttat atcagtctgt acttttaatg
      541 aaccagtagt gtttagttct atggaagacc aagatgaaaa agtacctgta aatttggctt
      601 tcgtattagg acttaatcaa ccacacagtc aattatctgt attaacagaa ttaatgggaa
      661 ttatgcaaaa taaagagtta gttgataagt tgatgagttc tactgataaa gaagaagttt
      721 taaagacact aaagtcttta taaaaataaa aaagtactaa aaataaaaaa tataaaaata
      781 aaaattatta ggaggaaata aaaatgaaaa aaatattagt agcatgtgga gcaggaatag
      841 caacatcaac agtagtttgt gacaaggtag agagattagt taaggaaaat aatatacaag
      901 cagaagttat acaatgcaaa atagctgaat gtgcaacaaa gcaagaagga gcagatttaa
      961 tagtatcaac aactatacta ccaacaactt ataatatacc agcaataaaa gcaacagcat
     1021 atataactgg agtaaataca gcagcattag ataaaaaaat attagatgct ttaaaataat
     1081 cctatcatag atacattgaa ataatatttt ataaaacaga aaaaggagga tttataaatg
     1141 gataaattat tagcagtagt acaatacatt ttaaatatgg gaccgacagt aatactacca
     1201 ataacaattg tagtactagg aatgatattt agaattaagt ttacaaaagc tttaaagtca
     1261 ggtcttacaa ttggtatagg atttgtgggt ataaacttag ttgtaaacct attaacatca
     1321 acactagggc cagcggctca aggaatggtt gaaagattcg gacttaattt aacagtaata
     1381 gatgttggtt ggccaacaac agcatcagca acatgggctt caccagttgc accaatatta
     1441 ataccagttt gtttattagt aaacttacta ttattatact tcaataaaac aaagatatta
     1501 aacgttgata tatggaatta ttggcacttt atagtagcag gtgcagttgg atatatagta
     1561 acaggaagtt atgtttgggc tatattctgt gcaatactaa tggagttatt agtactgttt
     1621 attgcagaaa agacagcaaa aaatgttcag gagttttatg atttagaagg tatagcatta
     1681 ccaactggtt caacagcttc atttgctcca cttggatatt tagtaggtaa atttgttgaa
     1741 aaaataccag gaataaataa aatacaagca gacccagact ctatacaaaa aagatttggt
     1801 atatttggag aaccaatgat gatggggatt atactaggta taatacttgg agcacttgcg
     1861 ggatatgatg tagcaggaat attcaatgta ggtatatcaa tgggtgcagt aatgttactt
     1921 atgcctagaa tggttagaat attaatggaa ggtttaattc caatttcaga atcaataaga
     1981 gatttcttac aagcaaaata tggagacaga gaactttata taggtctgga tgcagcagta
     2041 gcaactggac atccagcagt tatatcaaca gctcttatac ttgttcctat aactttgttc
     2101 ttagcagtta tactaccagg aaacaaagtt ttaccatttg gagacttagc gacaatacca
     2161 ttttatatgg catttatagt gtgttttaga aaaggtaata tagttcaatc agttataaca
     2221 ggaacaatag taatagctat atcactttat atggctacaa actttgcaga tgttcataca
     2281 caattattac aacaagcaaa tatgatgcca gaaggaacaa caatggttac aagtatagat
     2341 acaggtggaa acttgctaaa atggggaata ttgaaattat ctcaattagt ttcttcattt
     2401 ggaatattct agtatgtagt taatagagat tactcttttt tagtaaagta tgcgaaaatt
     2461 taacatttag cagctactaa aaaagagtaa tattttttat aaatttttaa aaatacaaaa
     2521 tacaagagga ggagatttat cgtgaaagca gcagtattac atggcacaaa tgatatgaga
     2581 tttgaagata tagaaataaa accatgtgaa agtgatgaag taaaaataaa agttatggca
     2641 gcaggaatat gtgggtcaga tcctccaaga gtattaaaac attggaaata tccagttcca
     2701 gctataccag gacatgagtt ttctggagta attgctgaag ttggtaagga tgtaaaaaat
     2761 gtaaaagttg gagatagagt agttgcaatt ccttttatac cttgtaatga atgtgaatat
     2821 tgtaaaagag gattattttc attgtgtgat aaccatggaa tgttaggagc taaaagtttt
     2881 ggagcttttg cagagtatgt aaatataaaa gctacaaatg tacttccaat aggagatatg
     2941 aactttgaag atgctgcaat gatagagcca ctagcagttg ctatgcatgg agtacttaat
     3001 ataggtgttc aagttggaga cactgtagct gtaatgggta gtggaacaat ggggcagttg
     3061 gtaatacaag gacttaaaat agcaggggca ggaacaatta tagcagttga tatatctgat
     3121 aataaattaa gagaatcaaa ggaattaggg gctgatataa taattaatgc taaagatatt
     3181 aacccagtag aaaaaataaa agaacttact ggtggaaaag gtgttgacat agctcttgaa
     3241 tgtgcaggtt caaaaataac tcaagaacaa tgtttactta taactaaaaa gaaaagtaag
     3301 ataggatttt tagggatagc atattcagat ataactttat cagaagaagc atttgaaaat
     3361 atatttagaa aagaactaga attaaaaggt ttttggaact cttattctgc accatttcca
     3421 ggacaagaat ggactaaggg aatcaatcta gttaatgaag gaaagataaa attaaaagaa
     3481 atggtatctc atagattctc acttgaagat acttacaaag catttgaaat gataagagat
     3541 agaaaagaag aatttaacaa aatattaatt ttaccacaag gggttgaaaa ataatgaaag
     3601 cagtagttaa aactaaacca ggctatgata atgtagaagt tttagaagta gaagaaccaa
     3661 aagctacagg agacaaggtt aaaataaaag tagaatatag tggtatatgt ggttcagata
     3721 tacattcatt taaaggtgaa tatgcaaata taaaagcccc agtaacatta ggtcatgaat
     3781 tttctggaat tgttgtagaa gtaggagaag atgttaaaaa tataaaagta ggagatagag
     3841 ttacatcaga gactactttt gcaacttgtg agaaatgtat atattgtgaa actaaagatt
     3901 ataacttatg cccaactaga aaaggtattg gtactcaagt aaatggaagt tttgctgagt
     3961 atgtattatc aagagaagaa agcatacatg tacttcctga aaatgtatct ttattatcag
     4021 cagcccttac agagccacta gcttgttgtg ttcatgcagc tcttgaaaag actactatag
     4081 aaagttctga tacagtttta ataataggac caggaccaat tggtttatta ttagctcaag
     4141 ttgttaaatc tcaaggtgct acagttataa tgtctggtgt tacaaaagat aaggaaagat
     4201 tagaaatagc taaaaatctt ggagtagata gaactgtaaa tgtaatgaaa gaaagtttgg
     4261 cagatgtagt gaatgaaatg actgatggaa atggagtaaa caaaggattt gattgttctg
     4321 ggtttatgcc agcagttaac gaagccttaa gactgcttag aaaaaaaggt actttcgtac
     4381 aagttggaat ctttgctaaa aaattaaatg aaatggacca agaagcaata atccaaagag
     4441 agttacaata tataggaagc aggtctcaaa agccaagttc ttggattaca gcattagatt
     4501 taatggcaaa tgggaaagta aatacagaag ctttagttac tagaactgtt ggtttagacg
     4561 aatttaaaga aggtattaca gctttaatga acggggaaga aataaaagta gcagtaaaat
     4621 cttaaaaaaa catttgtatt attttaaaaa aaattgtaaa atctactgta ggataaaaaa
     4681 atgtaaggtc ttaaaaaata acaggaggaa gaaagtatga gcactcttag agatcattct
     4741 aataatatta gaaaaaacat aataaaaatg gttgcagaag ctaaaagcgg acatccaggt
     4801 ggttcattat caatagctga tatgttgaca gtattatatt ttgataagat gaacgtatgt
     4861 gcagaaaatc caaaaatggc tgatagagat agatttgttc tatcaaaagg tcatgcagca
     4921 ccagctttat atgctacatt agcagaaaaa ggatttttcc cagaagaaga attaataaca
     4981 ctaagaaaat ttggttctaa gttacaaggt cacccagaca tgaaaaaagt agcaggaatc
     5041 gatatgtcta ctggttctct tggtcaaggg ctatctgcag caaatggtat ggcacttgca
     5101 ggaaaattag ataacaaaga ctatacagta tatactatat taggtgatgg agaaatccaa
     5161 gaaggtcaaa tatgggaagc tgcaatgaca gcatcacatt acaaattaga taatttaatt
     5221 gcatttgttg acttaaatgg attacaaata gatggttcta atgaagaagt aatgaatgta
     5281 aatccagtag atgacaaatt caaatctttt ggatggaatg taatagtaat aaatggacat
     5341 tcttttgaag aaataggaaa tgcagttgat gaagctaaaa aagttacagg aaaaccaact
     5401 gtaataatag ctaaaacagt aaaaggtaaa ggtgtttcat ttatggaaaa taatgctgca
     5461 tggcatggaa cagctccaaa tgcagaacaa gcagagcaag cattgaaaga tttagaagga
     5521 ggtctatagg aatgggaata gcaactagag aagcttacgg acaagtgtta aaagaacttg
     5581 cagaaaataa agatatagta gtattagatg cagatttagg aaaagctaca aaaagtatat
     5641 catttaaaga agttgcccca gatagatttt ttgacatggg gatagcagaa ggtgacatga
     5701 ttggtacagc agcaggtctt gctacttgtg gaaaaatacc ttttgcgagt acttttgcaa
     5761 tatttgcagc aggaagaggc tatgagcaaa taagaaactc tgtagcatat ccaaatttaa
     5821 atgtaaaaat agcagctact catgcaggtg taacagtagg tgaagatggt ggtagccatc
     5881 aagctataga ggatatatct ctaatgagag gtataccaaa tatggttgta ttaaatccag
     5941 cagatgcttt agaagcaaga caagctattc ttgcatctat tgattataat ggacctgttt
     6001 atataagatt aggtagagct gcaactcctg atgtaaacag tgaaaattat aaatttgaaa
     6061 taggaaaagg aactgtttta agagaaggtt ctgacataac agtaatagct acaggaataa
     6121 tggtagcaaa agccttagaa gcagcagaag aacttgctaa agaaggtata aatgtagaag
     6181 ttgttaatat atctacaata aaaccattag atgaagcatt aataaaagaa actgctaaga
     6241 aaactggaaa agtagttaca gcagaggagc acagtataat aggtggttta ggttcagctg
     6301 tatgtgaagc tttagcagaa actaaagatg tagtagttag aagaattggt gttaaagatg
     6361 tatttggtca atcaggtaca ccagctgatt tattaaaaca ctatggttta actacagaag
     6421 atatagtaaa aaatataaaa gagttattat agatataaat atatctaaat aacaaattga
     6481 tttgacataa gtcaattaaa gctgtcttaa aaatagaaag aaatttctac aatgggacag
     6541 ctttattttt acaatacttt atttttatga taattataaa atagtctgaa agtaatcaaa
     6601 aaaattataa aaagaggtgc tatttaatga aaatatctat tggatgtgac catggtggtt
     6661 atgaattaaa ggaatatata aaggaaaatt taataaataa aggtatagaa gttgaagatg
     6721 tgggtacaaa ttcaaaagaa agtgtagatt ttccaatata tgcaaaaaag gtaagtcaaa
     6781 atgttcaaag taaaaaatct gatttaggca tactttgttg tggaacagga ataggtatgt
     6841 ctattgcagc aaataagttt aaaggaatca gagcagctgt tgtttctgac tgtttttcag
     6901 ctaaggcaac tagagaacac aataatacaa atgtactttg tttaggagaa agagttattg
     6961 ggaaaggatt agcaatgaga attgttgaag aatggttaaa ttcaagttat aatggagaaa
     7021 gacatgcaag aagattacaa atgattgatg atatagaaaa agaaaattta taaatatata
     7081 atttataaca agggggagcg ttatgtctat tatttgtgct tcaataatgt gtgcagacca
     7141 aatgaagtta aaagaggaat tagaagctct tgaagaagca ggtgtaaaat tacttcattg
     7201 tgatgttatg gatggaatat ttgttaaaaa cttggctatg ggaccagagt tattaaaatc
     7261 aataagtgaa aatacaacaa tacctttaga catacactta gccacagaaa ctccagataa
     7321 atatattgat atgatgtctt atataaagcc aaaatatatt tcttttcatg tagaatcaag
     7381 tacaaatgta aaagctgata tacaaaagtt aagaaattat ggtatagggc cagtgttagc
     7441 aataagccct caaacaagtg tggataaaat agaagaatat ataagtttag ttgagggtat
     7501 cttagtaatg acagtaaatc cagggtttgc aggtcaaaag tttaatcttt ctgtattgga
     7561 taagttggat aaacttacag agatactaaa agattatgat aatcctccat ttatagaggt
     7621 tgatggaaat ataaataagg atactattaa acttatgaat ggtaaaaaag tagatatata
     7681 tgttgttggt acttcagctt tatttaatga taagcctcca atttcatata aagataaaat
     7741 agaagaacta aaagaaagta taaagtaacc atgtaataaa attataatat gtttctgttt
     7801 aatagtaaaa atttaggtgg aaacaagaaa ttttataata tttaataaaa attttggttg
     7861 agtaaggaga attttttatg ggagacctat ataaactaca aaatggtact gatattagag
     7921 gaatagcgta tgaaaatgat tctaaagaag ttaacctaac tgtagaagaa gtaaaaaaaa
     7981 tagctaaagc gtttcatatt tggttaaaag aaaagactaa gaaagataaa gtaactgttg
     8041 ccataggaac tgattctagg ataacaggaa gccaatttag aagtactgtt attgaaactt
     8101 taactaatga tgattgtaat gtaattgatt gtgagattgc cacaactcca gctatgttta
     8161 tgacaactat tatggatgga tacaattctg atggggcgat tatgattaca gcaagtcact
     8221 taccttatta ctataatggt ttaaagtttt tcacagaaag tggaggttta gaaaaaactg
     8281 atataaaaga gatgttggat atagctgtta aaaatgatag tgtagactat gaggaagtaa
     8341 ataaaaaagg tgaagttata gtaaaaaatt taatagaaga ttattctaat ttattaatag
     8401 ataaaattag aaaaggtgta aattcaagta aaaattatga aaagcctttt tctgggctta
     8461 agatattggt tgatgcagga aatggggctg gtggattctt tgctgaaaaa gttttacaca
     8521 tactgggagc agatacgaca ggtagtcagt ttttgaaccc agatggtatg ttcccaaatc
     8581 atatacctaa tcccgaaaac aaagaagcaa tggaaagcat atgtaaagct gtgttagata
     8641 ataagagcga cctaggaata atctttgata cagatgtaga cagagctgct attgtaggta
     8701 aaaatggcaa accaataaat aaaaatgctc ttatagctgt tatatcatca atagtattag
     8761 aagaacatcc aaaaacagct atagtaacag attcgattac ttctgaagga cttgctaaat
     8821 ttataaatga attacaagga agacatcata gatttaaaag aggatataaa aatgtaataa
     8881 atgaagctat aagattaaat agtgaaggtg aagagtgcca tttagctata gaaacgtctg
     8941 gacatgctgc tttaaaagaa aattatttct tagatgatgg ggcatattta atagctaaaa
     9001 ttttaataaa agtagcaaag ctatccttag aaggaaagac tatagaagaa ttgatagaaa
     9061 accttgaaga agctcaagaa gagaaagaag ttagaatagg cattaataaa gaagatttta
     9121 gaccatatgc agaggatata ttaaaagatt tagattctca tgtcaagagt attgatggat
     9181 ggtctgtagc accaaataat tttgaaggca taagagttaa ttgtgatgaa tcaaatggag
     9241 atggatggtt tttacttaga atatcactac atgaaccatt attagcttta aatattgaat
     9301 caaataaaat tggcggagca gaacaaattt attctaagtt aaaacttttc ttagaaaaat
     9361 atgatttaaa aggtctttag ggtaaataga aagaatatat ttatattgaa gaataaatgt
     9421 aaatttgtac ctaagattac aaatattaca aaattgtaat cttaggtaac agagatgtaa
     9481 ctgattatgg aaacactatg tgatattata gatacagaga gatgaaatat gtgatgaatt
     9541 atagagaaat ataatttaaa atgtattaat atcacaccaa aaaggtataa tcaaaaaata
     9601 tgtaaatata aaccccaaca tttagaaaaa gacctctaag gaggtttttt tcttgtttaa
     9661 ataacttaaa atatattttt atatcaatat atcaattaac tcttctaaaa gtaagcatta
     9721 ccttaaataa atcagcatct ataattattt ccatgtgtgc attttctaat tcaattatat
     9781 tttgagcaat tgataaacca agaccagagc catctgtttt tctagatata tcaccccttc
     9841 taaatctttc tattaactct tctggcttta gatttagttt atcatttgaa atatttttaa
     9901 acgttaatat tatattttct tcctttataa acatatctat atagacccta gtgttaggca
     9961 tagagtattt taatatattg caaattagat tctcaaaaac tctccaagtt tttttaccat
    10021 ctatcatggt aaaaacagca tattcaggtg tttctattat aaaatctaaa ctgctatttt
    10081 gaattttgtc ttcaaattct acaatacttt gaattaaaag ttctcttata tcggtttttg
    10141 ttatattaaa ttctacatct ccactactta gcttagatgc ttcaaatatg tcatctatta
    10201 ataattttaa tctttgtgat tttttatcta aaatatttat atagtcattt atagtctctc
    10261 tgtcaaagtc attatttttt aacatatcaa catagcttaa tatagatgta agtggagttt
    10321 ttaagtcatg agatacgttt gtgataagct ctgccttcat cctttcattt tttatattag
    10381 catctacagc agtttcaaga ccgcctgtta tattatttat acttttggct aaagtagata
    10441 tttcatcatc tcctataact tctaatttat actttaaatt gccattttct atatttttta
    10501 tattttttga tatgttattt atgtaattaa acttaacaga taaaaagttg tatatataaa
    10561 aatgaaaaac tgtgtttaca agtgtaaata aaattactat agctattgcc tcagcataat
    10621 atatatacat aaagaatatc aaaacaagat attggataat agcttgtaca actatagata
    10681 ttaaaaatac tatagctaat tttttattta tagttttttt attatacata ctaa
//
LOCUS       DAEQAF010000113        10672 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.117, whole genome shotgun sequence.
ACCESSION   DAEQAF010000113 DAEQAF010000000
VERSION     DAEQAF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10672
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.117"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            158..1318
                     /locus_tag="KRN00_003177"
     CDS             158..1318
                     /locus_tag="KRN00_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBH1829023.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            1660..1821
                     /locus_tag="KRN00_003178"
     CDS             1660..1821
                     /locus_tag="KRN00_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829024.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            2014..2643
                     /locus_tag="KRN00_003179"
     CDS             2014..2643
                     /locus_tag="KRN00_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBH1829025.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKEYTVEKIYLSDHYPVIGYI"
     gene            2882..4141
                     /locus_tag="KRN00_003180"
     CDS             2882..4141
                     /locus_tag="KRN00_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBH1829026.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKAITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            4400..5395
                     /locus_tag="KRN00_003181"
     CDS             4400..5395
                     /locus_tag="KRN00_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBH1829027.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQVKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            5641..6708
                     /locus_tag="KRN00_003182"
     CDS             5641..6708
                     /locus_tag="KRN00_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBH1829028.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKGKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            7242..9152
                     /locus_tag="KRN00_003183"
     CDS             7242..9152
                     /locus_tag="KRN00_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBH1829029.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNVGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEGYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(9215..9838)
                     /gene="ytaF"
                     /locus_tag="KRN00_003184"
     CDS             complement(9215..9838)
                     /gene="ytaF"
                     /locus_tag="KRN00_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBH1829030.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            10026..10670
                     /locus_tag="KRN00_003185"
     CDS             10026..10670
                     /locus_tag="KRN00_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1829031.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT         4365 a         1053 c         1755 g         3499 t
ORIGIN      
        1 aaatctttat taatatatgt caatagttag gtatatatgt atttaattag catgatatag
       61 ataaaagtat ttattttaat tgtctattat ctgaaaaagt ctttacttag aaatcataaa
      121 aatcaaatta attaggaaaa gaaagggtgt gtataatgtg attgagactg gatttgtata
      181 ttgtagtttc ttggttgtat tcgtaggtgt aatttttttt atggttgata aattgaaatg
      241 gaaggtattt gatgttatta atccaatgct tttaatatac ttaggttcag ctatacttgg
      301 atcatttggt ttatttgcac agaatgaaga tgttggaacg tatcaaaaca taataacagt
      361 gaacttcctt ccattaatgt tagtgttttt gttaattcaa tgtgatttaa gaaaaatatt
      421 aaagatgggg cctaaaatgt tattatcatt tttctgtgct acatttacat ttatgcttgg
      481 atttgttata gcattcataa tttttaaaaa ttcaatgggt gcagattcat ggaaaattct
      541 tggggcagca tctggttcat ggataggtgg ctcatcaaat atgattgcag cagcgaatgc
      601 tctaggagtt gcagaagaag gacttagtta tgcaatactt atgggttcta taggatatac
      661 agtatggatg tctgtttgtc taatgtctgt gaaatttgga cctaaattta acaaatggac
      721 aaagtgcgat acaagtttta tagatgaggt tacatcaaaa cttgaaaaag aaaataaaga
      781 taatacggca cctacgtttg tagaacttat gattttactt tctgttgggt ttggagttgc
      841 gtcttttgca caaattgtat ccaagatact tccaacttca ggtatactta atgaaactat
      901 gtgggtagta cttgttgcat ctacagtatc aatattattg ggtatgacaa aaatatcaaa
      961 gcttaaaggg agtacactgg taggaaatgt gtttatgtat ttactccttg cagctacagg
     1021 tagtaaagca aatttctttg gattgtcaga agcacctgtt tacataatgt ttggattggt
     1081 agtagtcctt gtacatgcta tttcatttat agggcttgct aaactattta aacttgattt
     1141 atttacttgt gaagtaggaa gtatagctaa tataggagga gtaactacag ctccaatgat
     1201 tgctggggtt cacaatcctg tattaatacc agtaggtgta cttatggggc ttctaggaaa
     1261 tattataggg acttattgtg ctcttatggt aactcaaata ttacatatgt tagcttaata
     1321 aaaatatggt ataaaattaa taatttaaat aagaaaagtc atttcaattt aagcagaagc
     1381 ttttactgaa atggcttttt tgtttgacaa gataatctat ttcaagaaga tgttttgaca
     1441 tatttagtgt ataatattgt aaaatttact aaaaacgaga tatatttaat ttttatattg
     1501 aatcgaacgt ctgtatgatg tataataaat atacagaacg aatgtttgca gaacgggtgt
     1561 tttttgaatt tattttaata atttatgaat atatatcata atgcataaat atatttaaat
     1621 ataaagatta aaaagaattt aaaggagtgt tgataactta tgataattcc atcaagaaga
     1681 atacaagata taacattaac aaatttaaaa aatggtgaag taactttaat tgaattggat
     1741 gaaatataca agaagatggg atttttattt gttgttagtg aaggcaaatt gaaaaagata
     1801 aaaaaggaga atcatcatta gaaatgaatg aaataataaa tattataata gtttataaaa
     1861 cctaacttat gtagaatata aatacttaag ttaggttttt ttgtgataaa gtttataagt
     1921 actcaatttt ataagataaa taatggtctt aagtgaaaag taaataagtt taaattttag
     1981 taagtattat attgcataag aggtgatatt attatgaaaa tagtaaccta caatattcat
     2041 aaaggtatgg attcaaataa tagattaact ctaactaaaa tggggttata tttaaaacaa
     2101 ttggattgtg atgtaatttg tttgcaagaa gtattatatc ctcaattttt agctttaaaa
     2161 gctgttttaa atatggatgg tgtctttgcg acaaatgtaa aaaaagtaaa tatgatatat
     2221 ggtatttgta catttacaac atctaaaatg ttaaacagta atcatttttt cttaactagc
     2281 aaaaaagaac aacggggagc tctttgtata actatagatg catatggaag aattataaat
     2341 gtaataaata ctcacttggg acttgatagg caggagagag caaaacaatt agacgaaata
     2401 atagactata ggaacagatt agtggggata gttattttat gtggtgattt taatgagaaa
     2461 aatgtctttt taagtatgtt taatgatatg gctatttcac taaacaagtc ttacttacca
     2521 acatttgaaa aatcaaactc tagaatagat tacatttttg ttaataaaaa tactgaacta
     2581 aaagaataca cagtagaaaa aatttacctg tcagaccatt atcctgtaat aggttacatt
     2641 taaatttcaa tataaatgaa attagttgtt ataaaataaa caattttttg ttaagaaata
     2701 gtaaaagaaa tataataaaa aatatcaaaa ataaaactaa ttataagaca taaatttaca
     2761 ataaagttac atttgattaa attccttgtt taacaaaagc tattcaaata taatctaagg
     2821 tagttttgaa atgggaactc tattatgcaa atttaagcta gtgttaaaat gaggtgaagt
     2881 tatgggcaga agaacaacaa gagtttcaag attaggtaaa gaaaaaaaac gaagtgtttt
     2941 aattgtattg gcagctttag ttctaataat gggtggattt acttattttt ttaacagtaa
     3001 atttctgtac aatgggaaaa tcgctaaaaa tgtatatata gaaggagtaa atgtatctga
     3061 tatgactaaa gcagaggcat taaaagctat aacagataag tatactccag aagatttaaa
     3121 tcttgcttat gatgggaaaa aatatacaat atcaccaaaa gatattgatt taaaatatga
     3181 tacagaagat gttgtaaaag atgcttatga aagtacaaaa aaagggtcct attttcaaaa
     3241 cttaaaaaaa tatattgata taagagtgaa taaggcaaat atgaagataa aagctgaata
     3301 tgatgaggca aaacttagtt ccaaagtgtc ttctatagca gatagtataa atgttaagat
     3361 gaaaaatgct tctattagtg ttggaagtgg tggactaagt tatacagact ctgttgtagg
     3421 tagagaattt gatttggcag caaataaaga gtctatatat aatatgataa aaaataaaga
     3481 gcataaaact ttagaactta aagtaaatct tcaaaaacca gatataacaa ctgaacaagt
     3541 aaaaactgta aattctgtta taggtcaata ttcaactact tattcacaag ctgtagaggg
     3601 taggtcatat aatgtaggat tatcagcaag aaaaactagt gatgtattat taatgccagg
     3661 tgaagaattt tcatacaata aacttacagg acctagtaat aaagcaaatg gttacaaaga
     3721 tgcacctgtt atagtttatg gtaagctaga acaatcagca ggaggaggtg tttgtcaaac
     3781 atcttcaaca gtttataatg cggctcttct ttcgggtatg gagataactc aagttacaaa
     3841 tcattcatct gcatctactt atgtgcctaa agggagagat gctactgtga gcgatggagg
     3901 attaaactta aagtttaaaa atccatataa gcatcctgta tatattaaaa attatgcagg
     3961 tggaggaagt gtatcatcag taatctatgg taattctggt gacaaaccaa atatatctat
     4021 agaggtaaaa caaactggtc agaataaata ttctacatat cgaatattta aagattcaag
     4081 tggaaaggtc ataaaaaaag aacatatatc aaatagttct tataaagaat taaaaaaata
     4141 gataattttt tagagaaata tttgtaatat aaaagggagt gtctcaaaat gaacttttta
     4201 gtttatgagg cactcttttt ctgtgaaatc aaatatattt tcatcatttc aacaatacaa
     4261 aagaagcgta tctctatttt gagacagcct tttttgtaaa aattaacact attagttctt
     4321 gttttaatat tacaatcatt aatatataga aaatattcct atatattggt ataattgtaa
     4381 atagatttag ttatataaaa tgtatgagga ggtgacatgg ttgaatttta taggcaatag
     4441 atatgaggta gtaaattctg atgacgtttt agaaattaac aaaatctata aagctagaga
     4501 tgttttttac aggaaaaatg tgttaataaa agttataaag cacaataatt atatctgtga
     4561 agattttgtt tcaaatttaa ttgatgaaag tactgcttta gatgagataa actctcctta
     4621 tatactaaaa ataatagatg ttgggattca ctgtacagaa gaaacaacat tatattatgt
     4681 tgtaagtgaa gactttaatg gtatcggact agatgaatta attctaggta attatcttca
     4741 tttagaagca attgtaaaca taatgataca agttttaaaa gctttagaaa tgatacatag
     4801 gaatcattca tatcatggta gtttaaaatc gagtagtata atagtagata cagaatacaa
     4861 tataaaaatt tgtgattttg gaattacaaa agcaaataat ggggttaata caagaagcta
     4921 tggaaacagg agatatttat gcccacatca actatgtata aattatactg ataaagaaag
     4981 tgattttttt gcaacaggtc ttattctatt tgaatctata tttaaaaaat tgccttttgg
     5041 agaatcaaat tcagaagaaa aaatgctaca atctattgat aagggattag attggaatag
     5101 tataaaagca attaatggaa atactgaact tataaatgtt ataaaaaggc ttcttggaag
     5161 aaataataag tataccagag ccaatgatat tattattgat ttaagtaaag taatgtatga
     5221 aaaagcatat atagaagttg aagatgagaa agaagaagag cagaaacaag acaaagttat
     5281 acaagttaaa aaagaatata aaagtaaaat gagaaaaaaa ttacataaaa aacttgttgt
     5341 tgccggtcta gctatagtca tgatttcaat gattattatt agttccataa tataaaaatt
     5401 gtatattaag tattttaaaa tcaatgtcta taaaggatat acatagaaat tttagtgtag
     5461 tcttaaatta tgaaaggaag tggttattat gttaacaaaa aataatgagg tattaaacgt
     5521 ctaggagtat tttaacaaat agccacctgc ttttacagtt tagaataaaa aagctgtggc
     5581 taaaggtcac agctttttgc tactttttaa aggcaggaga atattaaaaa ggagcaaatt
     5641 atgagcaata taaaaataat agcaagtaat aaatgttgga ttgaagatat agcaaggaaa
     5701 caacttgaag atatttcaaa gttaaatgga attttaagag tagtaggatt acctgactta
     5761 catgcaggta aaatacctgt aggtttagca gttgagacta aaaatattat ttatccacat
     5821 ataattggaa atgatatagg atgcggaatg actttattta aaactggggt tctaaaaaag
     5881 aaatttaaaa aagacaaatg gattaagtca cttagtaaga ttaaagattt gtctgatata
     5941 gaaataaaaa acacatataa agaagaatgt ccaattttaa atttaggaac tatagggagt
     6001 ggaaatcatt ttgtagaaat tcaatgtata agtgaaattt ataataaaga acaatttgaa
     6061 caattaaaat tttcatctga tgatattatg atgttagttc actgtgggtc aagaaattat
     6121 ggagaagata ttttaaaaaa attttatgat aaagatggac ttgaagttga aagtgagaaa
     6181 gctatagatt atattaaaaa acatgataat gctttaatgt gggcagagcg taatcgtgaa
     6241 gctatcagta aaaaaattat gcagtcaata ggtacatctg gagatgttga aacaatattc
     6301 tctataaatc ataattttat agagaaaagg gaagataaat ttatacatag aaaaggtgct
     6361 gtttcaagtg aaagaggagc tgtgattata ccaggttcaa gaggcagtct atcatatata
     6421 gttatgccta ctgaaaatac agagatatct ttatattctc tatcacatgg agcaggtagg
     6481 aaatggtctc gttcagtttg taaatctcgc cttaaaggta agtatagtaa agatactata
     6541 aaacaaacta aatttaaaag tcagattata tgtaatgatg taaatttatt atttcaagaa
     6601 gctccagagg catataagaa tatagagcag attattgaaa gtttgataga atatgaactt
     6661 attcaagtag tggcaactat gaagccattg attacttata aaggataatt tttaaagtta
     6721 aaaaagatta aaattatatt ataaatagct aattttatag aacatttaaa agtgttttat
     6781 tattagctat ttttttattt tgtagagacg ataatttata gagctaaatt ctttgatata
     6841 taatgattac aaagttagac tgtattggaa actgcacata catgaattga tgacaatata
     6901 agtgattcca aaatataaat gaaagtataa gcttattttc actataaaaa ttttcactgt
     6961 acaaaaacat taatgacatt atttttattg acataaatat ataatttatg gaataatatt
     7021 agaagcactt gtataagtgt ttaaataaga atagaaaagg agaagtgttt tatgaaaaaa
     7081 aatactaaca ttaatgagtc cggagttaaa cttcttaata aataaggagt ttgatatata
     7141 ataactcctt atttattaag ttgttcgcaa aataactatt atcaaagtaa atgatagggt
     7201 gatttaaaag acgatgactt ataaataaag gagaaaaaat aatgaatagt aatacatttg
     7261 aaagattaca actaaatgaa gttaaagaat taataaaaat acattgtgta agttcgctag
     7321 gaaaaaattt aatagataaa ttaactccta gtgggaatat tggagtagta agaaggaaat
     7381 tagcagaaaa taaagaagct agaaagataa ttgaaaatag taatcacata ccacttgaag
     7441 gattgtttaa tgtaggttct acaatagata aaattgaaaa aggaatgata atagaacctg
     7501 ttgaacttgt aaatattgaa gattttttaa gaggttgtag gaagatgaaa gcttttatgt
     7561 tagaaaaaga attttattca cctacattaa gttcttatgc cttaaatata acagaatgta
     7621 aaagtataga agatgagata aattactgta taaaatctaa taaagttgat tctaatgcta
     7681 gtaaagaatt aaaaaagata agacgaaata tagaaattac agaaggaaag ataaaagata
     7741 gattaaataa atttataaca tcaactgtaa ataaaaagta tatacaagag tttataataa
     7801 gtaaaagaaa tgatagatat gtaataccaa ttaaatcttc ttataaaaat gaagttaatg
     7861 gtactatatt agatacatca tcaaaaggaa atactgtatt tattgaacct attagtgttt
     7921 caaatttaag tacagagtta actatgctaa aagctgatga aactattgaa gaatacaaaa
     7981 tattatctta tttaacagaa cttatatttg agaagataag tcagataaaa ttaaatatag
     8041 agatactttc agaatacgat atggtatttg caaaagctaa gtatagtcaa aaaataaaag
     8101 gaattactcc aaaaataaat aataatggct atataaaaat aattaaaggt aaacatccac
     8161 ttctaacagg agatgcagta cctttagatt ttgaaatagg caaaaattat agaagtctta
     8221 taataacagg tcctaatgca ggaggaaaaa ctgtaaccct taagactgtt ggtttactaa
     8281 ctttaatggt tcaatgtgga tttgatattt ctgcaaaaga aggtagtgaa tttagtgtat
     8341 ttgaaaaagt ttttgtagat ataggggata atcaaagtat tgaaaatgcc ttaagtactt
     8401 tttcatcaca tataaaaaat attgcagaga ttatgagttt atcaaataat tctactcttg
     8461 ttctgtttga tgaaatagga agtggaactg aacctaatga aggagctggt ttagcaatat
     8521 cattattaga agagttttac aaaatgggat gtataactat agcatcaact cattatggag
     8581 agataaaaaa gtttgctaca ttgcatccag aatttgaaaa tgctggtatg atgtttgata
     8641 aagaaacgtt agaaccattg tataagttaa ctattggaaa atctgaagat agtaatgctc
     8701 tttttatttc taaaaaaatg ggaataaaaa atagagtttt agatagagct aaagaatatg
     8761 taattgatag aaactacaat ttagatttag ttaaaagaag taagctacaa tctaatattg
     8821 aagataaaaa tagttctgaa gtcattttaa actatacaga ttataatgta ggggataagg
     8881 taaaattact agatgaagat gattttggaa ttgtatataa acctatggac aagtttaata
     8941 atgtagaagt attgtttaat gataatttta tttcagtaaa tataaaaaga ttacaactta
     9001 gcataaaagc atcagaattg tatccagaag ggtatgattt agatgtatta tttactagtt
     9061 ttaaagaaag aaaattagaa aaagatattc aaagaggttc aaaaaaagct cttaaaaaga
     9121 ttcagaaaga aattagagag aatagaaaat aaatataaaa agcacaaaag aaagcaatct
     9181 aaagagaaaa gtttatcttt agattgcttt cttattaaca tatcttcata aatccaatga
     9241 ctaacaagat taaaccactt aaccaagata agtttaaatt tacgttttta acaaacatat
     9301 ttcctagtaa acagccaagt aatactgcaa ttatatttga tattaaagaa aatagaataa
     9361 cttgtatata attcacacct acaaggccac taccaaaacc gatagctaat ccatctaaac
     9421 ttaaagcaag tgcaagtgta aatgcttcag cagatttaag cactttagat ttacttgtat
     9481 ctaagacatc aggttcgata cttacattaa aatttaattt aaggtctaac atattaaaat
     9541 tataattctt tgagtgtata gattttttct taaaataaga tttaaaaaaa ctttcaatta
     9601 gtctagcact tcctaataaa aataaaataa agaaacatat taacattgtt atattttgag
     9661 gtaaaaagtc tctaactatt gtacctgcaa aaagcgatat tgctaaaata gctgaacaaa
     9721 ctacgctgat aattatattt gaatataagg gaactttaac tttatttaca ccatatccaa
     9781 agcttgtcac aaaggcatct atacaaagag aagtaactaa taaaattgat tcaatcacag
     9841 tagattaaca tcctttctct taaattttgt acttatatta gttatagtat tgtaaaaatg
     9901 gataaattgt tacagataat ccaataaatt gttgataaaa ttccaacatc atacaacacc
     9961 taaataacaa aagaatcata tcatataata atataaaacc aatcataata aagcaggtga
    10021 aaataatgga acaaaataat aaggttggga atttcggtga tttgttgaag attttattag
    10081 atgaaaaaga attatcaatg ggagaactaa gtaaaaaaag tggaattgat aaatctacta
    10141 tatctcgtat agctaataat aaacaaaagc caaatataaa tcatttagaa aagatggcaa
    10201 tacatttaaa tattaaccta gaagaactgt tgaaagcttc aggatatgaa tttagaaaca
    10261 gcaataatca aatatttaat gcagatagtg attttagtaa ctttgatgat attcttggat
    10321 ttgcaaattt aatcaatgat aagaacttta atggaaatat tgaaaaagag ttaagtaagt
    10381 gtaagttata tgtccaaaca gatgaaggta aaaaattact ttttgataat tttaataaaa
    10441 aaatagattc tattgaaaaa caaggtcaat ttacagatag attaagacaa atgtatgctg
    10501 atttttgtac agatggactt acaataaaga aatatttatt gattggaagt atgctacttt
    10561 actttgttat atcaacagat gtgattccag acttcgtgtt cccaatagga tttatggatg
    10621 atttagtagc attaaatata gttacaaaat tacttaaaaa tgataagtaa gt
//
LOCUS       DAEQAF010000114        10653 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.118, whole genome shotgun sequence.
ACCESSION   DAEQAF010000114 DAEQAF010000000
VERSION     DAEQAF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10653
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.118"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            228..1007
                     /locus_tag="KRN00_003186"
     CDS             228..1007
                     /locus_tag="KRN00_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBH1829032.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDVVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
     gene            complement(1317..2138)
                     /locus_tag="KRN00_003187"
     CDS             complement(1317..2138)
                     /locus_tag="KRN00_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallohydrolase"
                     /protein_id="HBH1829033.1"
                     /translation="MKLKIIGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGNVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEMWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(3082..3900)
                     /locus_tag="KRN00_003188"
     CDS             complement(3082..3900)
                     /locus_tag="KRN00_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1829034.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYEVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            4068..4649
                     /locus_tag="KRN00_003189"
     CDS             4068..4649
                     /locus_tag="KRN00_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1829035.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            4646..4840
                     /locus_tag="KRN00_003190"
     CDS             4646..4840
                     /locus_tag="KRN00_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829036.1"
                     /translation="MKIITIGSSLITVLLFLSTMVCGFWIKNNKVTDASSIKFHMNSA
                     IFTGIFLLISTIFLIIYIKK"
     gene            complement(5004..6746)
                     /locus_tag="KRN00_003191"
     CDS             complement(5004..6746)
                     /locus_tag="KRN00_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M3"
                     /protein_id="HBH1829037.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMNLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKYVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
     gene            7175..8551
                     /locus_tag="KRN00_003192"
     CDS             7175..8551
                     /locus_tag="KRN00_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBH1829038.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            8881..9552
                     /locus_tag="KRN00_003193"
     CDS             8881..9552
                     /locus_tag="KRN00_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBH1829039.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            9741..10538
                     /locus_tag="KRN00_003194"
     CDS             9741..10538
                     /locus_tag="KRN00_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBH1829040.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
BASE COUNT         3954 a         1288 c         1604 g         3807 t
ORIGIN      
        1 tataatcaat accgattcta taatataatt aacactactt tttaaatata atcaataccg
       61 attctataat attaacacta ttttttatgc tatataacaa ttattgaaaa tgatataagt
      121 ataatatctc aaatgatatg aatataacat ctgaatagag ggtgttttat ttgtaaaaaa
      181 taagtttaca gtttgagcgt ataaacttat ggcaaaggag aataattatg agttataaga
      241 agattgcaat tataacgggt gctaatagtg gttttggtaa agagtttcta aagttattaa
      301 taaatgaaga agaaataaca gaaatatggg cagttgcaag aaacaaggcg agattaaatc
      361 aattagtaga tgaatttgga agtaaggtaa aaattttttc aaaagattta tcaaaaatag
      421 aagaagtaaa agaaattggt acatttttaa gtaaagaaaa tgtatgtata aaatacctta
      481 taaacaatgc tggttttgca aaattctgtt catacaatga tttaagtata gatgaatcta
      541 ttaatatgat tgatttaaat attagtgctg ttgtagcatt gggacttata tgtattccat
      601 atatgcaaaa gggaagccat atcatgaata tttcttcaca agcatcattc cagccattgc
      661 catatcaaaa tatttatagt tcaactaaag cgtttataag aaattataca agagcattaa
      721 atgttgaact taagagtaaa gggataaatg caattgctgt atgtccaggt tggatgagta
      781 caaatctatt taagagaggt atagttgtag ctgaaaaagg gacaaaaaat ttcccaggca
      841 tagtgtctcc agacgttgtt gccaaaaaag cattgaagga tgcaaagaaa aataaggata
      901 tttctgtgta tggtataaat acaaaatcca gtcatttatt agcaaaacta ttgccacaaa
      961 aaatgatgat gaaggtttgg ttaatgcaac aacatattaa ggaataagag ttttggtaat
     1021 taagtatcag ttggagattc aatctgttat atattatgag aagttttgtt gagcaaataa
     1081 taattgtgac aaaacggctt atctagtgac gataagccgt ctataatgta tataaaatat
     1141 atttttgatt ttactttatt tagatattga agtattaaaa tatgtaggac ttgaaatttt
     1201 ataaagataa atactatgat actttgtaaa aactgcgata tgttgatatt acatagttta
     1261 actatactgt taaattgaag ttttcttatt ttgcattatg cttattactt aatgatttag
     1321 actataattt ccataccatc atatgcaaaa taaatgttat caagtttctt ttctaattca
     1381 ctgtaataac catatgattt tccccacatt tcgtcaatat gtgtaatgat aatcttttta
     1441 attctataat agtttttaat ttcaacaatc tcatctaaag taaagatttc atctttaaat
     1501 ggtgtgtctt taagttttgt accatcattt aatataccat catcagaaac tagacttatt
     1561 attaaaacat cagcatcaaa gtacatatca ctatgagtaa atggcttggg attacagcag
     1621 gcatatatga cttttttttc attctctttg ataacataga aggttatatt cctgtctggg
     1681 ttattgttaa tcaaatcaat atcaaaatta tttatcttta catgcgaagt ttcattaata
     1741 gaaatgcaat ttataacatt accataatat ttaagacaat cgagattcgt tcggtttata
     1801 tcttcaatta cttcaggaag cgcataaaag ccaattggat tattttctcc tgtgataaag
     1861 tcacatccta ttttttcgac aattctaata cccttaacat ggtctgggtc atggtgagaa
     1921 attgaaatat gttttacttc cgatattttt tgtctgttac aagctactgc aatgtcttca
     1981 ggtgtgtcta tcagcatttt tatatcatca atatataaac ttggccctaa tcgttcatat
     2041 cttccgcctt tttgtctggc ttcttcacat attttgcatt tgcaaaatga acttggaata
     2101 attgacatac cgccactacc aataattttt aatttcaaag ttattacacc accttcttaa
     2161 aatattagat tatataaata atatacaagc acaactgatt aacaaaatta tgagttaata
     2221 aattatatca catgcaaata tgaaagaata gtatgaaatt tttataaaca tatattaaat
     2281 gtttctcaat gaaattgact ttgtatatga actgaatgac ttattcaata tggataagac
     2341 atttttcttg taataagata tgattgtcct ataaggttta tgtaattttg atataatttg
     2401 atataatata ttgattaaca acatacatgt tattggtgag catatttcta tagaatggaa
     2461 tatataattt tttatattta tcattgtatt attgtctaaa gaaagttaaa aagagtagag
     2521 cacaaaggaa ttatttgtac tttactcttt tattgttttg ttaaaaaaac taatttatat
     2581 tagtgattaa aatatattta actagagtat aaggatagta tataatctta taattgattt
     2641 atctgacaaa ttaagataat atcctaatca aattctagtc atttaaatat aacatcataa
     2701 gtaatttatc tgacaaatta agataatatc ctaatcaaat tctagtcatt caaacataac
     2761 atcacaagtg atttatctga caaattaaga taatatccca atcaaattct agtcatttaa
     2821 atataacatc ataagtaatt tatctgacaa attaagataa tatcccaatc aaattctagg
     2881 tatttaaaca taacatcaca agtgatttat ctgacaaatt aagataatat cctaattaaa
     2941 ttgtaggtat ttaaacataa catcacaagt gatttatctg aaaaagtaag ataatatcct
     3001 aattaaattg taggtattta tacataacac taaaagtaat ttgtctaaca aattaaaata
     3061 ttatccaatt taatataaaa attacttctt tttaactggg aagcatacct ctgttaccca
     3121 attatcagga ttactatcgt tgccaggact tacatgataa atattaaaca taggaccatc
     3181 cacctcatag ttattatctg atatccaatt accaatagcc tcacaagcgt ctgcaacttg
     3241 attgaaattt ccattaacaa ttgcagttgc agcagtcaca cttggaacag tcttaaattt
     3301 aacatgttca gtatctttat actttccaga tacagcaact tgtacttcaa catctacata
     3361 atcttcttta tatccagtat cataaaaaac tgctttagaa tactttgggg gttcaatttg
     3421 aacattctgg tcttttgtct ctaaaaatgc ttgatgccat aacattcctt cgtcttgata
     3481 agttggtata acccttctaa gtgtcatcat atattttggt gcaaaattct ttatagttac
     3541 atcataattt ttcataatat catttcctcc aattctttta atagtggttt ctatttttaa
     3601 tagttttttc tgtgtatctt ctaattgttc ttttacttga gaatgatgga tatttagata
     3661 ttttatgaga ctttctttat cgttatattc tgtcaaaatt tcttttatag aatacaagcc
     3721 aaagcccata tcttttagtg catggattct gtttgtagta gaaagttggt ctgcactata
     3781 gtatctatat ccattagttt tattcgtatg agaaggagtt aaaagtccta tttcatcata
     3841 atgacgtaac atacgaatac taattttact tagctttgaa aaatcgccta tcttaaacat
     3901 gtttttgtct cctttataaa ggtactttta gcttaatatt aatataaacc atatcataat
     3961 gttagagtca actaaaatta taattaaatt atattgacat atgatgaaaa aaatattata
     4021 ctgaacatgt tcagaaccga aaatgttaat tgttttggag gtctattatg aaaagtaatg
     4081 ataaagatgc tagagaacgt ataattgaag ttacattgaa tcttttaaat gaagtagatg
     4141 atattgagga aattacagtt agaaaaattg ctgagcgtgc aaatgttgga gttggtttaa
     4201 taaattatca ttttaaaaca aaggataatt tgttgagtac tgccatagga gatgtgatgt
     4261 caaatataat agcagagcta tatgacgata gtgtatatac tctaagacct attgaagatt
     4321 tgaaaaattt attaaaaaaa ttgtgtgata ctggattaca ttatgaaaaa gtgcttcctt
     4381 ttgtattgaa tcaatgtata accaatggag atatgcaagc agaacttgat attgtcccta
     4441 tgcttcgtaa aatttttgga aataaaaaag atgaaatgag tctaagaatt attgccctgc
     4501 aaattatttt accaatacag atttctgctt tatctacaga atcatttcag ttatacagtg
     4561 gtataaatat aaagaataaa tatgagcgag ataaattcat tgatatttta atagaaaata
     4621 ttattggaga ggatgttgat gtaagatgaa aattataact attggttcaa gtcttatcac
     4681 tgttttactt tttctttcaa ctatggtttg tgggttctgg attaagaata ataaggtaac
     4741 agatgcaagt tctattaagt tccatatgaa tagtgctatt tttacaggga tatttttatt
     4801 gatttccaca atctttttaa ttatatatat aaaaaaataa taatattatt aataaataaa
     4861 gtatcagaaa ttataaagac aagagtctta aaaatttctg atactttacc atataatttt
     4921 attaaacatt aattgtgtgt gaaaaaatat cacttatttc aatctaatac taaatcttaa
     4981 gaatgagtat aaagtattag aaattaagaa gcatttttta gttcaagtgg attatctata
     5041 ccaaaataat catataaagt agagcttatt tcctctaaat ttccatcttg gaaaggtaat
     5101 tgtaaattta ccttttctac cacatattta aatccagcat cagtattttg atttaaaaaa
     5161 tccatatata catcaacagc ttttctgtaa tcttcttgtg ataattgcca tatctgaagt
     5221 gatacatcag atgcaagacc ataactcaag taataaaaag gaacttggaa gttatgagat
     5281 acaagtatcc aaaaaggagc atttttttct ctaagtatat tattggaaac tccatattct
     5341 tcctctaaat caaaaaacaa tttattgata tcatttagat tcatatatgg attcttgtat
     5401 ataatttctt gaaattcatc ataaagacaa gcatcaataa tagtatttaa aacaatcgat
     5461 aagtgttctt tttttatagc ttcagattgt ttaccaaaaa aatcatcaaa atatttataa
     5521 aatagaattt ctaaagatgt tgaatgaact tcacatacat ctatacttgg ttgcatctta
     5581 ttatttaagt taatactgtt gtagtaatta taaaaatgac caaactcatg agcaaaacta
     5641 gtaacaccta aaaaagaatt gtcccatgta ttaaacaaga aaggtgcttt atatttattt
     5701 atataagtag tatatcctcc aggtgatttg ttttttccag aagaataatc gtacaagtca
     5761 tattttttca tatagtcgaa gctctctttt agttttggag atatatcttc aagtacttta
     5821 tcaaacttcc taaatgagcg atttttatat actttaatat aaatagaaga atcagatggt
     5881 ttagatgaaa tctctctata taatggaact atgtaatctt ttacatcttg tctaaatttt
     5941 ttagcttctt cttgagaata gtctttgttt aggttcatat aggcataatc tatataattc
     6001 ttaaatcctt gcttacttgc tatttcagtt cttgtctgta taagttctaa gaatatgtta
     6061 ccaaatatag gattgtattt ttttaagtaa tctgaataaa ttttcacata ttcttcaggg
     6121 ctaagatttg gtcttgacaa ggcttcttca aagtctacct ctataccatc tattgatact
     6181 gtagatttag ctaataaatc ttcatatttt acaactaggt cttgctcttt tttaagcaaa
     6241 ccttcaactt ctttagaatt aagttttcca atgttcttta gataattaaa tgtatccttt
     6301 ccaagttctt tttctaattc tttagagaat ttagaagtta caaatctatc ttgaaagtct
     6361 ttgtatgaca tgtcaacatc tactgattta ctcataagat acttatattc cttagagtaa
     6421 aattcgtctg atgaatctat gttatttcta atttttgcta tagtaagtgt actgtaaaaa
     6481 tcctgataaa ttttatcaac ttcattaaat aaatttaatt gttccttagc tgttttagct
     6541 gttaaaagtt tgtcgttaca cttgttaatg ttttcgcaaa ttgactgtat attaggacgc
     6601 ttatattcca ttttttcaaa aggaatagtt cctctaacag aatctttttt tgtatcatta
     6661 gtataatttc ttatgtatga tgcaaatata ataaaaactg caattaaaat tagaaaaaca
     6721 aatattttct tcttggattt aaccataaaa atcctccaat catggatata gttattaatt
     6781 attttactat attaaatata aaaaatgcat gttaagaaaa tttaacataa agatatagat
     6841 aagattataa ataatataaa aaatttaact tcaaaaaagt atatgaaatt tatactggta
     6901 aaatgataaa taaattttaa gtacaaaata gtaaaagcta tgatagtttt agacctatta
     6961 tatgtaaaaa atatagatgt ttttggtgca atttaaatta aaagatatat ataaaaattt
     7021 aaaatattcc aaacagaaat tataaaaatt actatcattg tctttataca atatttatac
     7081 tataatagaa taataattta gaggaaagct ctaaaaataa acaaattaag ggtcttaaca
     7141 gtagtgattt tatgttaagg aggtataaag aaagttgaaa acaatagtta gaagacttat
     7201 tctctacgca gatggaatgc gtcctactca aataatggta tctgggtttg ctgcgattat
     7261 tgtaatcgga gcattgttgt taacactccc gatagcgtcg cagagtggag agagtatagg
     7321 cttattaaat gctctattta cggctacttc agcggtttgt gttactggtc tagttatggt
     7381 agatacagca acttattgga gtttatttgg acagatagtt ataataacat tgatacaaat
     7441 tggtggtctt ggatttatga ccgtagccac aatgttttca cttatggcac gaaaaaaaat
     7501 acaactaaga gaaagattat taatacaaga gtcattaaat caagctgatt tatcgggact
     7561 tgtaagactt acaagatttg tattaataat aaccataaca atagagggaa taggtgcact
     7621 ggttttatca actgtcttta ttccacaatt tggtttgtct aaagggatat ggtatagtgt
     7681 atttcacgca atatcagcgt tttgtaatgc cggatttgac ttgatgggca gtgtaagtgg
     7741 cccatttaca tcgttaaatt cttatgtaaa caactttaca gtatcaatga ctgtttgcgc
     7801 acttatagtg cttggagggc taggattccc tgttgtactt gatattgtaa gaaaaagaag
     7861 attttcaaaa ttaaatgtgc attctaaggt tgtattgttt tcaactgcta cacttatttt
     7921 tgtgggtgca ttatttattt ttcttataga atttaatcaa aaagctacta tggcggactt
     7981 gcctttaaag ggaaaagtac tatcagcaat atttcaatca gtaacagcaa gaactgctgg
     8041 ttttaatacg cttgatttag ctactttacg agaaagtagt gtatttgtaa tgataatttt
     8101 gatgtttatt ggagcatcac ctgcatcaac tggtggaggt ataaaaacaa caacactagc
     8161 tgttttaatc attacagtta gaagttttct atcaggaaaa tcagatatag aagcttttga
     8221 aagaagatta gctccatcaa ctataaaaaa atctcttggt atatttgtaa tcagtatatc
     8281 agcagttatt tttggaacat tgattatttc aataactcag cctaatttta cattagttca
     8341 atcagctttt gaggttacat cagcacttgc tacagttggt tcaagtttag ctggaactcc
     8401 aaacttaaat gctttaggta agattataat aataatcttt atgtttatgg gtagagttgg
     8461 ttctcttact ttatttatgg ctatactttc tggtggtaga agaaagagtc aaccaatcag
     8521 atatgcagaa ggtaaaatta tggttggtta agttaccaag gagtaatata aatttataat
     8581 ggatttagag tagcactgta aatctgttga taaaataaat gagtctagat gtaattatat
     8641 gaagaaataa aatcgactaa tgaacaaaat taattaatga aataaaaaaa cagggaaata
     8701 aaatacaaat aaaaaggtaa atcaaaatta atctgtgtat ataaaattat atattgtgta
     8761 taagttttgt atgtgtaaag tatataagtt ttgtatgtgt aaagtatata agttttgtat
     8821 gtgtaaacaa ttaatttaag agatattata taaattgtgt attagggagg aagtttcgag
     8881 atgaagcaat atatagtcat tgggtgtggg agatttggaa gttcagttgc gtctactatg
     8941 catcttttag gacatcaagt aatggcaata gacaaaaatg aagattcagt tcaaagtata
     9001 tctgacaagg taacccattc acttatagtg gatgttactg atgagcaagc gttaaggtca
     9061 ttaggtttag gtaactttga tgtagcagta gttgcaatag gttctgatat aagggcatct
     9121 ataatggcga ctcttatagc caaagaaatg ggtgtagagt tgataatatg taaggcaaag
     9181 gatgaattac aagctaaagt tctttataaa attggtgcag atagagttgt atttccagaa
     9241 agagatatgg gagtaagagt tgcacacaat ttagtttcgg ataatatatt agaccatatt
     9301 gaacttgacc cagagtattc aattgttgaa atcgtaactc caaatagttg ggttggcaag
     9361 acacttatag agcttgaatt aagagctaga tatgagataa ctgtacttgc tataaaaaca
     9421 ggtaaaaata taaatgttac accttctcca gatgaggaac ttacagccgg aagtatccta
     9481 gttataatcg gtcaaaatac tagtataaca gcgataacat ctggaaataa ggggataatt
     9541 agaagaagat aatttactat ttaatatata tttaattgca atgaaagtag atagtatcat
     9601 ataattatga atagttatat gatactattt ttttaatcga aggtagtatt tatttgtaag
     9661 attagataaa gagaagttaa attaaaagta aggaggctgt gctaatataa aaatttataa
     9721 gttattagca tttagataaa atgattacaa atataaacag taaggataat gaaaagttaa
     9781 agtatacaag agcactatta aaatcaaaga ataggaataa agagtcaaag ttcataatag
     9841 aaggatacag aatagtaatg cttgcacttg aatgtatggc aaaccttgat tatgtattta
     9901 tcaatgaaga atttgaaaat aagaaagaac atgtaaaact attagaagat ttggataaaa
     9961 aaaacacaaa gatatacaag actactaata aaaactttaa agaattagtg gatacagaaa
    10021 atactcaagg aataataggt gtagtttcat ttaagaaaaa aaaattaagt gaaagtataa
    10081 ataaaaaaga taaatttgta ttgattttag acagaataca agacccagga aatatgggga
    10141 ctataataag gactgctgat tctgctggag tagatgccat aatagcacta aagggatgtg
    10201 tcgatatata caacccaaaa gtaattaggt ctactatggg ttctattttt gatatgaata
    10261 taattgatgc ttcacaagat gaaactgtgg acatgcttaa atcattggat tttaatatag
    10321 tttcaagtta cttaaataca gaaaattttt atgacaaaat agattatggt tcaaaagtag
    10381 cattggtgat aggaaacgaa gcaaatggaa taaatgaaga acttgtatca aagtctgata
    10441 ttttggttaa gatacctata tatggtaaag ccgagtcgtt aaatgctgcg ataagctctg
    10501 ctatactgat gtatgaaata aaaaaatact taatttaatg tattgtaata aatataatgt
    10561 catgttataa tcttgaatta aatagtagag tatcaaaaat agtcaatata tattaaaaaa
    10621 ataattaaat taattatata ttagatgtat att
//
LOCUS       DAEQAF010000115        10587 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.119, whole genome shotgun sequence.
ACCESSION   DAEQAF010000115 DAEQAF010000000
VERSION     DAEQAF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.119"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            41..1741
                     /locus_tag="KRN00_003195"
     CDS             41..1741
                     /locus_tag="KRN00_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829041.1"
                     /translation="MKRYLKTYGVALIIVIIYAFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            1911..2528
                     /locus_tag="KRN00_003196"
     CDS             1911..2528
                     /locus_tag="KRN00_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829042.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            2889..4082
                     /locus_tag="KRN00_003197"
     CDS             2889..4082
                     /locus_tag="KRN00_003197"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBH1829043.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEENLVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            4100..5392
                     /gene="lysA"
                     /locus_tag="KRN00_003198"
     CDS             4100..5392
                     /gene="lysA"
                     /locus_tag="KRN00_003198"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBH1829044.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            5609..6268
                     /locus_tag="KRN00_003199"
     CDS             5609..6268
                     /locus_tag="KRN00_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829045.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNSNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(6423..7508)
                     /locus_tag="KRN00_003200"
     CDS             complement(6423..7508)
                     /locus_tag="KRN00_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBH1829046.1"
                     /translation="MIIISKENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            7699..8415
                     /locus_tag="KRN00_003201"
     CDS             7699..8415
                     /locus_tag="KRN00_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBH1829047.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            8473..9051
                     /locus_tag="KRN00_003202"
     CDS             8473..9051
                     /locus_tag="KRN00_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1829048.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVELIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            9445..10317
                     /locus_tag="KRN00_003203"
     CDS             9445..10317
                     /locus_tag="KRN00_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBH1829049.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
BASE COUNT         4371 a         1113 c         1842 g         3261 t
ORIGIN      
        1 tataatagta ataataacat tttttagaga ggagtattaa atgaaacgat atcttaaaac
       61 atatggagtt gcattaataa ttgtaataat ttatgcattt attaaattac ctgtactaag
      121 attagatttt acatctttat tttcagtagg aataattttc tttgttgtag caggaatact
      181 agatatgatg ttagatagaa atgaaagagc atctaaaatg gctaaatata atttttcaat
      241 agcaatagct ttgcttgtgt atattgtagt agttcccttt ataacttcta cacctgtact
      301 tcatgcaaaa tcatatagag aactattggg aaaagtaact gaaagtaaat ttactgatga
      361 cattagccct gtcagtgtaa atgacattcg tcttgtagat gaagatatgg caatgaaatt
      421 aggtgacaaa aagcttggag aagttcctgc aatagggagt gtatccaaat taggaaaatt
      481 tcatatacaa aatgtagatg gagagttgta ctgggtagcg cctcttgttc acagagacat
      541 aattaaatgg ataacatctc taagtggtac aagtggttat gtaaaagtat cagctagtaa
      601 tcctcaagac gtccaattag ttcaagaaat agatggaaag ccaataaaga tagtttacca
      661 accagaagcc tacttacatc aagatttaca aagacattta tacatacatg gtattgtaaa
      721 tgttggtatg acagatttca ctcttgaaat aaatgatgaa ggaagacctt attgggttgt
      781 aagtttatat gaacataaaa ttggctatgg aggagcaaat gcaacaggaa tagccactgt
      841 tgatgcagaa actggaaaaa taaatgttta tgatgttaaa aacacaccta aatgggtgga
      901 tagaatacaa ccacaaagct ttgtaacaga ccagattaaa gactggggtg tttatgttaa
      961 tggattttta aactctgtta tatcagaaaa gggagtttta gtaccaacag aaggtacatc
     1021 attagtttat ggcaatgata acaggtctta ttggtataca ggtataacat cttcaggtgg
     1081 agatgaatct acaattggat ttatgttagt tgattctaga acaaaagaag ctagattata
     1141 taaacaacca ggagctactg aaacggctgc aatgaaatca gctgaaggta atgttcaaga
     1201 aaaaaattat gaagctacgt tccctgtaat gtataatata ttgggtcagc caacatatgt
     1261 atcatcatta aaagataagg ctggtcttgt taagagagtt gcatttgtat ctgttgaaga
     1321 ttataatgta cttggaatag gtgaagataa gaatgaagca ttaagaaact ataaggatgc
     1381 attagaatct aagggtaatg atttaaaact tgataatgat ttaaaagatg aggtattaga
     1441 aggcacagtg acaagaataa gcccagatgt gcgaggtggt aacactaatt attatgtaac
     1501 tttagattca aataaagata taatatttag ggctacttca aaagtatcta gcgaattgcc
     1561 attgactcag gttggtgata aagtcaaaat atcgtattca aaagaagaat ctggtgtaat
     1621 agaaatgtca gaatttgata acctaaatat tgcaaacttt gaagataaaa aagcaaaaga
     1681 aaaaacagga actgatgaaa atacagattc caaagattct gaaaatcaag gtaatgtata
     1741 atttaaataa aaagattgat aatagtattt aacatagtga tagctaattt ttatagaatt
     1801 taattctata aaaattagct attttatttt aattctttgt aaatttaatg tcataaaatt
     1861 aatataatat tagtacaact ttgcaaataa tacttcaagg agaatgtact atgacgaata
     1921 tggaaaaaga gatattactt ttaattagca gggttagatg tgttacagag tctcaattta
     1981 gaaaaattta tggagaccaa aaaagataca ataaaaaaaa ttttaaaaaa actttgagaa
     2041 aaatgtgtag tgaatataca ctaaaaaaat atccttgtga tgtggattat tataattata
     2101 aagacctctc ttatgtatac tatttaaacg gtagtaaact ttttaaggga gatgatttaa
     2161 taaaggctct agtaggatca gaattagttg ttagaatcaa tactgcaggt tgtgatgtaa
     2221 aaagatttta ccgaaatgtt agtgtagatg atgtgaaata cgatttattt attgaatata
     2281 cagaccaatt tggtaatata aagcaagttt tagttgatgt tgacttaaat aatgaaatag
     2341 acatttctaa atacgaaaat ctttctaaaa aaatagataa atctacaatt ccatttttta
     2401 aagtaccaaa cgttttggta gttacaccag ataatctatc cgaattaaat gatttagaga
     2461 gatatgataa tgagtatagc ataaatttta tagatttagg attaaataaa ctatttaatt
     2521 gtatataagc taactttaga aaagaaaact atcgatttgc cacattttgt aaaataattg
     2581 ttgcaatatt atatagaata tgataaaact atattaataa attaattaaa aataatgagc
     2641 ctagggtaga ggtagctgta ttcaatagta ttcaatagga gctggtaagc gttgataatt
     2701 gatgaaaggg tatatagccg aagaaatttt gttgacggac aaattttctg gacttatgca
     2761 gaatatgcat aaggctgtca cttttaaagt ggtgagctac aaggttactt ggtctatgaa
     2821 atttacacgt ccaaagtata cctttgggcg tttttattta tcaaaattta gcttgagggg
     2881 gagaaagcat gagtataatt gttcaaaaat atggtggaag ttcagtagca gatactgaaa
     2941 aaataaaatc aatagcagaa aatataatag aacgaagaaa agaaaatcca caaatggtaa
     3001 tagttgtatc tgccatggga aaatccactg atgaatatat aactttagca aaggaattga
     3061 gtaatgaacc tagtaagagg gaattagatg ctttaatgtc tactggtgaa atgatttcag
     3121 catctttatt atcaatagca ttaaatgcac ttggatgtaa agctataagt tataatgctt
     3181 accagttaaa tataaaaacg agtggtcttc atggaaagtc tcaaattgat gatataaacg
     3241 taaacagaat taaaaatagt ttagatgaag gaaatgtcgt gatagtaact ggatttcagg
     3301 gaatcaacga agatggtgat gtaaccactc ttggaagagg tggttcagat acatctgctg
     3361 tagctcttgc ggttaaatta aatggaaaat gtgagatata tacagatgtt gatggaattt
     3421 attttacaga cccaagaaaa tattcaaagg ctagtaaact tgatgagatt gaatatgaag
     3481 aaatgcttga gttagcgagt ttaggagcac aagtaatgca ttcaagaagt atagagcttg
     3541 cacaaaaata tggtgttgaa atctatgtcg gacgtacatg tggtacagaa aaaggaacat
     3601 atataagagg gggaaaagac atgaaattag aggataaagt aataacagga ttagctacta
     3661 gtgatgatga cagttctata acaataaaag attttaaagc tgaaaatata tctagcttat
     3721 ttgaagatat agcaactata ggtataagtg tagatatgat aagccaaact gcacctattt
     3781 tagataagat aagtgtatca tttacagttc caaaagaaga gttgggagaa tgtaaaaaga
     3841 tagtatctaa atatacagat gaagaaaatt tagtgattga taataatatc actaaatttt
     3901 ctttagtagg tcttggtatg aaaaatactt ctggagttgc tgctaaagta tttaagatat
     3961 tcaatgaaaa tggtataatg ataaaactta taactacatc agagattcgt ataacttgtg
     4021 ctataaattc tgatgataag caagtagcta tagaaaaaat agcagaagta tttaatatat
     4081 aaaatttggg gaggctatta tgaaacttca tggaactatg actgtaaata atgatgaatt
     4141 atatattgga ggagtgagtt gtttagaact tagtaaaaaa tatcaaactc cactttatgt
     4201 atttgatgaa gctttagtta gacaaaattg tagagaatat atagaatatt ttaaggctag
     4261 agagggaaaa aataaggttg cttatgcagg gaaagctttt ttacctcttt acatgtgtaa
     4321 tcttataaat gaagaacaaa tgtgtttaga tgtagtttca ggaggcgagt tatatacagc
     4381 ttataaatca aattttccta tggaaaaagt tttctttcat ggaaacaata agactaaaga
     4441 agaaataaac atgggattag atttaggtgt aggtaaattt gtagtggata atttttatga
     4501 attagatttg cttgaagcat tatgtgaaga taaaggtaaa actcaagaga tatactttag
     4561 aataactcct ggtatagaag ctcatacaca tgattatata aaaactggac agatagattc
     4621 taaatttgga tttgctttag taaatggaga tttatttaga gcaatagaaa aattaagtga
     4681 atataaaaat attaaacttg taggtcttca cgctcatata ggttcacaaa tatttgatgt
     4741 agaaccatac atagatacag tggatataat gatgaacttg gtaaaagaaa taaaagaaaa
     4801 attcaacata caactaacag aaattgacct aggtggagga gttggcgttt attatagcga
     4861 aggagataaa cctaaaacta taaaagagtt ttgtgaaacc ataatcacta aagcagaaac
     4921 ttcatgtaaa gagcttggaa tagaagtacc tacattggta atagaaccag gaaggtcaat
     4981 agttgcaaat gcaggaagta cattgtatac agtaggttct ataaaagata taaaagatgt
     5041 tagggtttat gtaagtgtag atggaggtat gacagataat gtaagacctt cgttgtacca
     5101 agctagttat gagtgtagta ttgtgaataa aattaatcat gaggctatga atcatgtaac
     5161 aatagctgga aaatgttgtg agagtggaga tatattaatt ggagatataa acataatgga
     5221 tattaaaagt ggagatatac ttataacaac atcaactggt gcatatggat attcaatgtc
     5281 ttcaaattat aataaaatac caagagcagc agtagtatca gtatttgatg gaaatgataa
     5341 gataatttgt aagagacaaa gctatgagga cttattagct ttagagatat aaaatagaga
     5401 agtatataat aaaaattaaa tattaaagtt tattatgagc agatttgcta ggatatgtat
     5461 ctctaaatta atttttggtt tattgtatcg ttcgtagcat atctgcttat tttttgtttt
     5521 actaacaaat ttcttgtaat aaatataaaa tattttaaaa actttataat tatgataaaa
     5581 tttaaagtat atgacaagga gggatttaat gagaggaaga gtaattttat taatatcgat
     5641 attatctata tttcttgtag gatgttcatt taataaaaaa gatgaaataa atttagtaga
     5701 gcaaggaaaa acatatttag aaaaacataa ctataaaaaa gctatggaat cattatcctc
     5761 tgcactggaa gaagatagta ctaatgagaa tgcaagagct atgtatatgc aagctatgag
     5821 aatgtcaaat atgacggagt ttgaagaatt aaaaaattat gagggtgcaa tcaaggaact
     5881 taaacttata gagaaaatca aaaatggttc ctctgttatt aaagaagagg caactaaaaa
     5941 gaaagaagag ttaactaaat tagaaaaaga acaaaacgaa gcagaggaac aaagaaagaa
     6001 aaaggcaaaa gatacggctg gagaagatag gtatagagtt gaatcagatg caaggaaatc
     6061 ttcttatagt ggaagtagta aaaataataa atctagttct aaaaataatg ataaaaaatc
     6121 agatagtaat aagtctgaca atagtaacag ctcttctcaa aatcaagaaa agccaaataa
     6181 tagtaatcca acaccagcac caactccaca agatactact ggtggttcag atagtggtgg
     6241 aaattctcaa aactcaaata atcaataagt ataaaatata tgcataaatt taatgaacaa
     6301 attatatatt ataaaaaata tctcttagca attttttctt actaagagat attttttgag
     6361 aaataattta ataaataaca gttaaatttt aaactaaaaa ttaaagtcac agtagagatg
     6421 agctattgta aacgattatc tatatattta tcaacataag tttttacaac agcagctatt
     6481 ggtactgaaa gaaaaactcc tatgaaacca aatagagatt gtcccaccaa aatagcagat
     6541 attacccata tagctcctat accaacttga ttacccataa cttttggttc tataaaattt
     6601 ccatctaatt gttgcaatat aaatagaaat gcaatgaccc atatagtttt ttgtggacta
     6661 tataatatag tcatggctat tggagggatt gcaccaataa aaggaccaaa atagggaatt
     6721 atattaccta agaatattat tgaagctaaa aataaagcat tttctattct gataacaaat
     6781 tgaaatccta aaaatgcaat tataccaata ataagagagt ctaatattct accaagtaaa
     6841 taatcataga aaatatcatg agtagtccta aaaaattcta taatgttatc tgccttgttt
     6901 ctagcagtag aagaatatag aaatctctta aatcccaatg caattttttc tttgtcatat
     6961 ataatgtata tggatagtat aaatcccatt gtcatattaa atagcataga agatatacta
     7021 agtgtataga ttaagaagtt tttaggaatt ttaccaacaa aattacttgc ttcttttaat
     7081 aaattatcta aactatgttg tatatgagga attaaagttt ttagaaaatc tatgtttgac
     7141 atattttttt ctataaaact atctatataa tcagtataca taggcatttc atttatcaat
     7201 ctatttaatg tattagctat tgatggaatt aataacctaa tggcaaaggc taaaataaaa
     7261 cctataaata tataagataa aaaaatggct aaaagtctat gtgctttgaa ttttacctca
     7321 aaaagcatca caagtggatt taaaagtaaa gcaagtaaaa tagctaataa aaatgggcta
     7381 aaaaacttta agaatccttc aatactagat ataaagtctg atggagtatt aataaattta
     7441 aaaaataaaa ttccaataaa tacgactatt aaataatatt ttatattttc ctttgaaata
     7501 ataatcactt ccttaaaata gtgtttagtc agctattaca tattaatagt atgtgaaaag
     7561 aaattacaat tatttaggaa aattaaataa tttttttgct tgtttttaat taaggtctag
     7621 tatagtataa taatgtagca aaattaacat tgataaaaat attaaacaca cataatttaa
     7681 gataaggaag gattaagtat gagaattaat aagtatatag cttcttgtgg aatagcatca
     7741 agaagaaaag cagaagaaat aattcttgga ggaagaataa aggtaaatgg aagtgtagta
     7801 aaagagttat cttttaatat tgatgaagaa aaagacatag tagaatttga taataaaaaa
     7861 gtaaaaccaa gtgaaaatta tatatatata gtattaaata aaccagaggg atatataact
     7921 acagtaaaag accaattcaa tagacccagt gtaatagaca tacttaaaga tgtaagggaa
     7981 agagtatatc caatagggag attagattat gaaactagtg gattattaat acttactaat
     8041 gatggcgatt taacatataa gcttacccat ccaaaacatg aaattgataa aacgtatgtg
     8101 gcaagtgtga agggaattat aagtgatgat gagataagac aattcgaaac aggactaaaa
     8161 atagaagatt acacaacggc acctgccaaa ataagggtaa ctaaagaaaa taaagaaaaa
     8221 aattattcag tgtgtgaaat aactatacat gagggtagaa atagacaagt aagaaaaatg
     8281 tgcaaagcta taaatcatcc agttttaaat ttaagaagga tttctgtggg gaaaatagta
     8341 ttaaaagaca ccaaagttgg agaatataga tacctaacag aagatgaaat aaaatattta
     8401 aaatcaataa aataagataa aaataaattg agaaaaaatg aaataaagtt aatagtaggg
     8461 agaaatagta ttatggcata tgcaaagtat ttaactaaaa ttacagatat aaataaattt
     8521 tatttagaaa atattataaa tgaaggtgac atagtaattg atgctactat gggaaatggg
     8581 tatgatacaa ggtatctagc tgagaaggtt ggagaaaagg gctttgtata tgcttttgat
     8641 atacaagaag aagcaataaa gtctacaaga aagaaactag agaaagaagg atatacagat
     8701 agagtagaat tgatatttga tgggcatgaa aaaatgaatc aatatataaa agaagaagtt
     8761 tcatgtgttt tatttaattt gggttatctt ccaagagcga aacattcaat tataaccaaa
     8821 ccagatacaa ctttaaaggc tataaagtta agtttagaaa tgttaaaaga aaatggagta
     8881 ataagcattg ccatatatac agggcatgat ggaggtcaag aagaaaaaga ttgcatatat
     8941 aaccttgtca ataatttaaa tcaagatgaa tttaatgttt tagaatctaa gtttttaaat
     9001 caagtcaata acccaccaca attgatttta attgaaaaga aaaaagcata ataaatacta
     9061 aaaaacttga caagattgta ttaagagtta atatatatag tgtgacctat taaaaatact
     9121 ttaaataata agtatacaac agcttatttt caaaacaaaa tatacatcta aatatgcaaa
     9181 ataagataga taacttttaa atgagtaaaa attgaaaaat ttaaaagaaa tattggataa
     9241 atattaaaaa atgcaaggaa agatggtata ataaatttaa tcgaaaatac tatgtgaagt
     9301 ataaggtaca gaaaagttag aattttatga gtttaagaag ctatgataaa aactaagatg
     9361 aaattgagat aaaaaataaa atttttagag aaaaagacag tgttaataaa acaaaatagt
     9421 ttatataact aaaaggagaa aaaaatggaa gaaacaaatg aaatgaagga cagtaaacat
     9481 ttgatatcaa atatacaatc tcaatatacg agattgagta agggtcaaaa acttatagca
     9541 caatacattt taaataatta tgataaagtt gcatttatga ctgcatgtaa attgggtgaa
     9601 accgtaggag taagtgagtc tacagttgta agatttgcaa atgcattagg ttatagtgga
     9661 tatcctaaat tacaagctgc acttcaagaa ctcataaaaa ataaactaac tacagtacaa
     9721 agagttgaaa tggcacatga ttattccgat gattttgcaa tactaaacaa agttttaaaa
     9781 agtgatatag ataatataag gtctacacta gaagaaattg acgagagagc gtttaaagaa
     9841 gcttctaaca aacttttaag agcgagaaaa atatatatac ttggaatgag gagttctttt
     9901 gtagtagctc aatatttagg tttttactta gatataatac ttgacaatgt tcatataatt
     9961 agaatggata tgggagatgc ttttgagcag attgtaagaa taaatgaaga agatgtaata
    10021 gttgctatta gtttccctcg ttattctaag aaatcttatc aaattgtcaa ttatgctaag
    10081 gaaaaaggag cccatgtaat atcattaaca gatagcttat ttgcgccagt agcatcactt
    10141 gcagataaca ctcttctagt taagagtaat atggcttcat ttgtagattc tctagttcca
    10201 gctcttagta tttcaaatgc ccttgctata tctgttggga tgaaggaaaa agaagatatt
    10261 aaacagcatt ttgatgattt agagcaaatt tggaaaagat attctgtgta tgagtaaagt
    10321 ttgtatatta ataaggctat gaaattgaga atcatagcct tattagtaaa tactcgatta
    10381 tcacttaaaa aataaatttt cgtttaaata atacaaataa atatttcgag actcaaaaca
    10441 taaaggtgta ttctgaatac atctttacta cgtcaactaa tttattaaag aaagcatttc
    10501 cattcatgga gagtgctttt tttatttctc taaacaatat catttcctta attaacaatt
    10561 ataaaattaa ttttatttgt atttaag
//
LOCUS       DAEQAF010000116        10303 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.120, whole genome shotgun sequence.
ACCESSION   DAEQAF010000116 DAEQAF010000000
VERSION     DAEQAF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10303
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.120"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            374..1534
                     /locus_tag="KRN00_003204"
     CDS             374..1534
                     /locus_tag="KRN00_003204"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBH1829050.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            1536..2666
                     /gene="glgD"
                     /locus_tag="KRN00_003205"
     CDS             1536..2666
                     /gene="glgD"
                     /locus_tag="KRN00_003205"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBH1829051.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            2695..4137
                     /gene="glgA"
                     /locus_tag="KRN00_003206"
     CDS             2695..4137
                     /gene="glgA"
                     /locus_tag="KRN00_003206"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBH1829052.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSIN
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            4151..6571
                     /locus_tag="KRN00_003207"
     CDS             4151..6571
                     /locus_tag="KRN00_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBH1829053.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            6576..8441
                     /locus_tag="KRN00_003208"
     CDS             6576..8441
                     /locus_tag="KRN00_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBH1829054.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGISILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKKADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            8686..9339
                     /locus_tag="KRN00_003209"
     CDS             8686..9339
                     /locus_tag="KRN00_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1829055.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            9435..10034
                     /locus_tag="KRN00_003210"
     CDS             9435..10034
                     /locus_tag="KRN00_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDOD domain-containing protein"
                     /protein_id="HBH1829056.1"
                     /translation="MYPNKEIAIEELEVAGKMNPGPWIKHSYNVANVAKLIAEQCENL
                     NSEKAFVCGLLHDIGRRTGISSVRHIIDGYDYVISKGWDEVARVCLTHSFPVKNIEAD
                     IGNKDISKEQYDFINHYLNNLEYNDYDKLIILCDALADANGFCILEKRFVDTTRRYGI
                     YPFSVERWNKTYEYKEYFEKIINKSIYTLLPNIEKSIYY"
BASE COUNT         4144 a         1001 c         1872 g         3286 t
ORIGIN      
        1 ctttggataa ttatttaaca aatattagat tatattttgc tattacgaat ttaacaaatt
       61 aaaaaataag catgtttata tgacacaagg gatttataaa aaatgttttt atatttataa
      121 aataaaattt gtattatttt ttaaccgata attgaatatt aataaatact atagtgctta
      181 tggaaaataa tgtatacgtc ggtaagtcca ttatggggta tacattatat caattgtata
      241 gttgatatta ttttattttt attaaggtat tatttaagca acatttatac acgacattta
      301 ttgactgata aagtttataa aagtaaaaat gcaattataa atattaatta ctagatgagg
      361 ggagtgtcat taaatgaaaa aagagatgtt agctatgatt ttggcaggag ggcaaggttc
      421 aagattaggt gtttttacaa aaagaattgc caaaccagct gtatcatttg gaggtaagta
      481 tagaattata gattttgtgt taagcaattg ttcaaactct ggtattgata ctgtaggtgt
      541 tttaactcaa tatagaccgt tgatattaaa ttcacatata ggcatgggaa gtcattggga
      601 tttggacaga ataaatggtg gtgtctatgt tttacaacca tttatgaatg aaaaagaagg
      661 aaattggtat aatggtacag cacatgcgat atatcaaaat atggactttg tagataccta
      721 taatccagaa tatgtattga tattatctgg tgaccatata tacaagatgg attatagcaa
      781 aatgttaaaa tttcataagg aaaaaggctc taaagctaca atagcagtga ttgaagttcc
      841 ttgggatgaa gcttcaagat ttgggataat gaatacaaat gaagattcaa gtatctatga
      901 atttgaagaa aaaccaagtg aacctaagag caatttggca tctatgggag tatacatatt
      961 tgattggaaa atgttgagaa attattttaa ggaagcagaa aaaaatccag aaataaatta
     1021 tgatgatttt ggaaaaaatt taatacctaa aatgttagaa gataatgttg gaatgtatgc
     1081 ttatccattt aaaggatact ggagagatgt aggaactata caaagtctat gggatgctaa
     1141 tatggatata ataaaatctc cagaaacact tgatttagca gaccctaagt ggaagatata
     1201 tacaaatact atggcaatgc ctccacaata tataggtaaa aatgcaaatg ttcatagatc
     1261 aatgatagct gatggttgta gaattttagg tgaagtaggt aactctgtat tatcacatgg
     1321 agttgttgtt ggtaaaggaa gtaaagtaat tgattcagta ataatgccaa atgttgtaat
     1381 aggtgaaaat gtaactatag aaaaagctat gataggtgag tgtgcaacta taaatgataa
     1441 tgttcagata aagaatgtaa ataatgaaat aaatgtagtt tctgagtatg aaaatatcga
     1501 acctagatgc gtattaatag aaggaggtct ttaagatgag aaatgaatgt ttagggataa
     1561 taaatttaaa caaaaaagga gacccagcaa taaacaaact taactatgga agaccaatag
     1621 catctacacc aatagctgga agatatagaa taatagactt tgctttatct aatatgataa
     1681 attcaggaat cactaaagtt ggaatattcg caaaagaaaa atacagatca ttaacagacc
     1741 atataggtag tggtaaagat tgggatttaa gtagaaaaaa aggtggccta tcaattttta
     1801 gtccagaaaa cactaagtat agaaatactt actcacatag agaaggtgat atatatacta
     1861 tcttagctaa tctagattat atagaaaaga gtgaagaaga atatatttta atagctccaa
     1921 gttatatgct atgcaattta aattattctc aagcattgga ataccataaa aaatctcata
     1981 atgatataac tataatatat aaaaatgtaa ataatgcaaa taaagatttt gctggtaact
     2041 taactctaaa tttagatagt aacaataggg taataaatgt aggaaataat ttaggtaagt
     2101 tccctagagc aaacatatgt atggagacat atattatgaa gcgtgaagat tttgttgaat
     2161 gtatatataa cattgtaaat aaaggcaatt attgttattt agaagaattt attattgaag
     2221 aagcagaaaa catgaaaata ggagcctatg aatatacagg atatctaaaa tgtgtaaatt
     2281 ctgttgaatc atattttgaa atgagcaaag atttattaaa tttagaagtt gcagatgaat
     2341 tattatattc tgaaagaaag atatttacaa aagaaaagaa tgaatcacct acaatttata
     2401 cagatagtgc taaagtagaa aatagcttta tagcatctgg ttgtttaata gaaggtactg
     2461 taaaagatag tatcatattt agaaaggtaa atgttgaaaa aggaacagtt atagagaact
     2521 caatagtaat gcaaaattgt gtaataaagt caaatgcaaa actatataat gcaatattag
     2581 ataaaaatac gagtgtatca aatgggaaag aattaagagg agatgaaaaa tatcctcttg
     2641 tagtggaaaa gaatacaaat atataaataa attttttaga agggggaatg actaatgaag
     2701 gttttttatg taacagcaga gtgttggccc tttgcaaaaa ctggaggatt aggagatgtt
     2761 tcttatgcat tgcctaaaga attaaaaaaa gaaggtgtag atgtaagggt aataatgccc
     2821 aaatattcaa ctataccaag ttatttaaaa gatcaactaa aagaaatagc tgtgtttagt
     2881 gtacgtgttg gatggagaaa tcaatactgt ggtcttttag aaatggaatt agatggtgta
     2941 aaattttact ttatagataa tgaattttat tttagaagag aagatgaaag aaagagtatc
     3001 tatggatatg gagatgatgc agaaagatat actttcttta cagatgcagt tttagaagct
     3061 ataagtagaa ttgattttta tccagatgta atacatataa atgattggca tacagggatg
     3121 ttaccattaa ttctaaaaga aagatatgca acccttgagg ggtataaaaa tataaaaact
     3181 atgtatacta tacataatct ccaatatcaa ggtgtatttg ataagcatgt tttatatgat
     3241 atattggatt taccacaaaa atactttgat aatggagata tagagtatta tggctcaata
     3301 aattttatga aagctggtat aaattttgca gataaaatta taactgttag tcctacttat
     3361 gcaaatgaaa tacaaacatc tttttatggc gaacaattag atggattact tagaaaagag
     3421 tcaggaaaat taaaaggtat attaaatggt atagattatg atttaaatga ccctgcaaaa
     3481 gataaagata tatttgttca ttatgatgta gactcaatta acaaaaaagt agaaaataaa
     3541 ttgagattac aagatatatt gggactaaaa aaagattcat ctattccgtt gataggtata
     3601 gtttcgagat tagtttctca aaaaggattt gatttaatag catacatgat gccagaactt
     3661 atgagagaag atttacagat tgtcgtttta ggaactggag aacatcaata tcaatcaatg
     3721 ttcaactatt acgattctaa tttttcagat aaagtatcag ctagaattac ttttaatgca
     3781 tcattggctc aacagatata tgctgcaagt gatatgttct taatgccatc attatttgag
     3841 ccttgtggta taggtcaaat gttagctatg agatatggtt ctttaccaat agttagagag
     3901 actggagggc ttagagatac agtaacacct tataataaat ttactggaga aggcaatgga
     3961 tttagtttta aaaattacaa tgctcatgag atgtttttct gtttgaaaaa tgcaatcaaa
     4021 gtatttaagg acaaagaaaa atggattaaa ttagttgaaa atgcaatgaa aacagataat
     4081 agttggaaaa aatcagctaa ggagtatata gaaacatata gagacatatg tgattaaagg
     4141 agtggttttt ttggtaacaa taagcaaaaa gaaattcaag caaaaatttg aagtaaaaat
     4201 gtatagctta tatgcacaat ctatcaagga agctactgat gaacaattgt taaatgtatt
     4261 atgtagtcta ttgaaagatg agatagcaaa aaaatgggtt gctacaaagt tagataagaa
     4321 aaaagaagtt tattatttta gtttagaatt tttaataggg agacagttaa aatctaattt
     4381 attaaattta aatattgaag aagaagttag agaaggttta tctgaattag gaatcaactt
     4441 ggatgattta attgaagctg aagtagaccc agccttagga aatggtggac ttggtagatt
     4501 agcagcttgc tttttagatt ctatggcatc tttgaacata agtggtcaag gatatggaat
     4561 aaggtataaa tatggtctgt ttgaacaaaa atttgtaaat ggttatcagg tagaagtgcc
     4621 tgataactgg cttacagaag gacgatatgc atgggaaact gtaagaccaa atgaagcaac
     4681 aatggtgaag tttggtggtg aggtagaatt aatcaaggaa ggtagtcatt taaaagtaat
     4741 tcataaaaac taccttcctg taatggcaat gccttatgat ataccaataa tcggatacca
     4801 aaaccaatgt ataaatactt taagattgtt taagagtgaa ataccaaaga gagattttgg
     4861 tgaacttacc tcaaatgctc taaattattc tggtagctat gaagaggctt taaaacataa
     4921 gtattatact gaggaaatat cacaggtatt atatcctgat gattcaaatt atgcaggtaa
     4981 gttgttgagg ttgaaacaag aatacttttt tgtaagtgca gggatacaag atataataag
     5041 aaaatataaa aagaacaaat taaatattaa taatttattc gataaggtag caattcatat
     5101 aaatgataca catcctacct tatgcatacc agaacttatg agaattttgc ttgatgaaga
     5161 aaatttatct tgggatgaag catgggaaat aactaaaaaa acagtgtcct atactaatca
     5221 tactataatg tcagaagcaa tggaaaaatg gcctgtaagt atgatgaaag agctattacc
     5281 aagaatttat atgataatag aagaaataaa tagaagatat gtagaggaat taaataataa
     5341 aggatatgac caagatagaa taaaaagaat gagtataata gactgtgaca atatcaatat
     5401 ggcaaactta tgtattgtca caagtcatag tgtaaatgga gttgctaagc ttcatactca
     5461 tattcttgaa acagaggtat taaaagattt ctatcaagat gaaccaaata aatttaataa
     5521 taagactaat ggaattgcac ataggcgatg gcttataagt tcaaatcctc aacttagcaa
     5581 tttaattaca gatttaattg gtgattcatg gaagaaagat acattacaat taaaaaatat
     5641 tgaaaaattt aaaaatgatt cctctgtttt acaaagactt gatgatataa aatacaataa
     5701 taaagcaaat ctagcaaagt ttataaaaga taaatacgat ttaaatgtag acccaagttc
     5761 gatatttgat gttcaagtta agagattgca tgcgtataaa agacagttac tgaatatatt
     5821 taatgtactt catatgtatc atgaattact tgataatcct aatttgaatc ttgacccaag
     5881 aacttttata tttggcgcaa aagcagcacc aggatattat ttggctaaat gtataattaa
     5941 atttataaat tctgttgcaa gtactataaa taatgatgtt agagtaaagg acaagttaaa
     6001 agtagtattt ttagagaatt atggagtatc attagcagaa ataataatac cagcagcaaa
     6061 tgttagtgag caaatttcaa ctacaactaa ggaagcatct ggaacaagta atatgaagtt
     6121 tatgatgaat ggtgctataa ctttggctac acttgacggt gcaaatgtag agatatgtga
     6181 acaggttggt aaagaaaata tgtttttatt tggacttagt gcagaacaag tactaaatta
     6241 taataaatat ggtggatatt cttcacttga cctatatcat tctaatatgg atataaaaag
     6301 ggtagtagat gatttaataa atggatttat tcctaatctt ggcgaagaag gaagaagtat
     6361 ttataattca ctcactactt acaatgatga gtattttgta ttgagagatt ttgaaaatta
     6421 tggtcaagct caagcagata taaacaggtt atatagagat aaagaaaaat ggaataaaat
     6481 gtctttagtt aatatagcta actctggatt tttttcttct gatagaacaa tttctgagta
     6541 tgcaaaagac atttggttta aaagggtgtg attaaatgca aagtgtaata gaatataact
     6601 cttgggataa aaattttaag gctccgtttg gagctttaaa atttgatgag gaattgacca
     6661 tttgtgttaa agtaaatgag ggatacaata tcaagtctat ttccctagaa ataaatagag
     6721 aagaagaaat gagaacaata actttaaatg aagaattaga taatgataaa cttggaaagt
     6781 gcttttgtgg taagattgaa aagtttgatg gtacaggtgt ttatttttat tactttaaag
     6841 ttgatgttga aatggatggt caaataaaga ctttatttta tggaaaaaac agagataatg
     6901 gatattcttg tgaatataat tatagtgata ttaataaata tcaaatcact gtttataaag
     6961 attttaaagt accaacatgg tacaaagaag gaatacttta tcatatattt gtagatagat
     7021 tcaataatgg aaatcgtagt ggtaaggttg ataatcctaa aaaaaatagt ttcatatatg
     7081 gaaattggga agatacacct atgtacataa aggatagtca aggggatgtt ataagatggg
     7141 atttccatgg tggaaattta agagggataa tcaataaact tggatattta aaaaaattag
     7201 gtataagtat actatatcta agccctatat ttgaagcctc tagtaatcat aagtatgata
     7261 caggtgacta taaaaaaatt gacccaatgt ttggggatga agatacattt aaagaactta
     7321 ttgataaagc aaaagaaaaa ggtatatcaa tagtattaga tggagttttt agtcatactg
     7381 gagcagatag taaatatttt aatatgtatg gaaactataa tagtttaggg gcatatcaat
     7441 ctaaagaatc tccatattat tcatggtata tgtttgaaga atttcctcaa aaatataaaa
     7501 gttggtggga tgttaagaca ttgccaaata taaatgaatt agaacatagc tatatggatt
     7561 atataatata tgacaatgat agcgttataa ataaatgggt aaatatgggt attaagggct
     7621 ggagactaga tgttgcagac gaattaccaa ctaagtttat aagagagtta aaaaaggaat
     7681 taaaaaaggc agatgatgac tcaattctta taggtgaagt atgggaagat gcatcaaata
     7741 agattagcta tggtcagaga agaagttatt tattaggtga agaattagat tctgttatgg
     7801 gttatccttt tagaaataac atgttttctt tcttaaaagg agaaattaat tcatatgaac
     7861 tttgtaatag atatatgcag attaaagaaa attatccaaa agaatcattt aggtctaatt
     7921 taaatttaat tggaacacat gatgttacaa gagctaaaac ggaattaaat gatgatgtag
     7981 atttagtgaa gcttgctgta gctatacaga tgacatttga aggagtacca tatatatatt
     8041 atggagatga agcaggtctt tgtggaggtg ttgacccaga taatagaaga acttatccat
     8101 ggaaaaatga agacgaagat atgcttaatt tttatagaga tgttataaaa attagaaata
     8161 agaataaact tttaagttct ggaaatacag aatttatata tactaataat gattctgtat
     8221 tttcttttat tagagttaat gaaaataatg atagaatgtt aattttagta aatagaagtg
     8281 aaaatgtgga aagtatatca ttatgtatag agagtagttt tattgaggaa atacctataa
     8341 agtatagtct taaaaatgca aatagtacta tacaaattga aaataatgag ttgaaagtag
     8401 atttagactc taaatcattt agaattttta gagtaaatta aatatctttt tttagaaaaa
     8461 taaatagaaa ataaggtgaa tgtggaaaga gttttgtttt atcaaaactt tttctacttt
     8521 ttttgtataa attatcataa gaattttagt atttcaaaat attacaaaga agtataaaaa
     8581 atatcataat tgtgatatta tataaattag taagataaaa ctgaactctc taccaaagtt
     8641 gtagggagat ttaactttta taatcttaat atggaggaac gtcttatgaa ggtagatcca
     8701 cttacaactc aagtatatga ctatatatca aagaaaatcc aaaatggaga gtatgaagct
     8761 aatcagagaa ttactgaatc tgagatttgt aaatctatcg gagttagtag aacaccagcg
     8821 agagaagcat taactaggtt agcaggtgaa aatttactag aaaaaatacc taataaggga
     8881 tttgtagtaa aagaatttca ggaaaaggag aaattagaca cctattccgt aattggagta
     8941 ttggatgcgt tagccggttc ttcagcatta caaaatttaa ctgaatcaga cctagtaaaa
     9001 atggaagaat taacagaaat gatggcggtc tctataaagt ataaaaatta caatagctat
     9061 ttaaaattaa gtaatgaatt tcacgatata tacataacta aatcagataa tcaggtgtta
     9121 gtaaatctat tgaactcttt aagatataat tttatgtcaa agtcatatac tagtgataat
     9181 gaagatgagt tatataaaat gttgacatac agcaataatc aacatattga agtagtaaaa
     9241 tctatgaggg agaatgattt agaaaatgtt gaaagagttt tgagagaaca ttggaaaacg
     9301 atacctatag cagagatgaa aaaagagaag cttttataaa gtttctcttt attttttata
     9361 ccattttatc actatttttt tgaattatta agtagaaaat aataattaat ttaaacttga
     9421 ggaggaaaac taatatgtat ccaaataaag aaattgcaat agaagagtta gaagtggctg
     9481 gcaaaatgaa tcccggtcca tggataaaac attcttacaa tgttgctaat gtagctaaat
     9541 tgattgcaga gcaatgtgaa aatttgaata gtgaaaaggc ctttgtgtgt ggattattac
     9601 atgacattgg aagaagaact ggtatttctt ctgtaaggca tattattgat ggatatgatt
     9661 atgttatttc taagggatgg gatgaagtgg caagggtatg tttgacacat tcttttcctg
     9721 ttaagaatat agaagctgat attggaaata aagatattag taaagaacag tatgatttta
     9781 tcaatcacta tttaaacaac cttgaatata acgattatga taagttgatt attctttgtg
     9841 atgcattggc agatgcaaat gggttttgta ttttagaaaa aagatttgtt gatacaacac
     9901 gaagatatgg aatatatccg ttttcagttg aacgatggaa taagacttat gagtataaag
     9961 aatatttcga gaaaataatc aacaagtcta tatatacatt gttacccaat attgaaaaat
    10021 ctatatatta ttaaatccta agttaataac ttaatatcca gtatcaccag cagttggtca
    10081 ttatgattga ctgcttttat tctgcttata ttaaaaaaat acactatggt ttgtgtatat
    10141 caaagttata tggaatgaaa agagaattta ttttatcaat taaaaaattt aataaatttt
    10201 atattaaaat taaaatacaa aaataggaaa attatttagt ccaactaaac caagaatttt
    10261 gatatgtgaa ataagaataa tataaaagtt tagtaataaa ata
//
LOCUS       DAEQAF010000117        10139 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.121, whole genome shotgun sequence.
ACCESSION   DAEQAF010000117 DAEQAF010000000
VERSION     DAEQAF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10139
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.121"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(40..1116)
                     /locus_tag="KRN00_003211"
     CDS             complement(40..1116)
                     /locus_tag="KRN00_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBH1829057.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(1489..2004)
                     /locus_tag="KRN00_003212"
     CDS             complement(1489..2004)
                     /locus_tag="KRN00_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBH1829058.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(2367..3437)
                     /gene="leuB"
                     /locus_tag="KRN00_003213"
     CDS             complement(2367..3437)
                     /gene="leuB"
                     /locus_tag="KRN00_003213"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBH1829059.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(3444..3935)
                     /gene="leuD"
                     /locus_tag="KRN00_003214"
     CDS             complement(3444..3935)
                     /gene="leuD"
                     /locus_tag="KRN00_003214"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBH1829060.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKRGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(3950..5227)
                     /gene="leuC"
                     /locus_tag="KRN00_003215"
     CDS             complement(3950..5227)
                     /gene="leuC"
                     /locus_tag="KRN00_003215"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBH1829061.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(5184..6926)
                     /gene="leuA"
                     /locus_tag="KRN00_003216"
     CDS             complement(5184..6926)
                     /gene="leuA"
                     /locus_tag="KRN00_003216"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBH1829062.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGNDYDAENISQTC"
     misc_binding    complement(7050..7296)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7444..7890)
                     /locus_tag="KRN00_003217"
     CDS             complement(7444..7890)
                     /locus_tag="KRN00_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829063.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(7911..8630)
                     /locus_tag="KRN00_003218"
     CDS             complement(7911..8630)
                     /locus_tag="KRN00_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBH1829064.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLKHLDYIIASL
                     HRPCIASGTKEKNTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(8748..10022)
                     /locus_tag="KRN00_003219"
     CDS             complement(8748..10022)
                     /locus_tag="KRN00_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBH1829065.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAELQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
BASE COUNT         3068 a         1959 c         1064 g         4048 t
ORIGIN      
        1 attctaaatt tatcttaaaa catacatatt tttacaatat tatttattaa aacctaatat
       61 atcatcaata ttatctaata attcttgtac atcttcgaca gtatagtcac ccatatgtga
      121 aattctaaaa gttttttctt ttaaatctcc atagccattt gctatttgga atcctcgttc
      181 ttgtaatttt gaatttaaat ttgatacact aataccttga gtattttcta taacagtaag
      241 tgtattggat aagtgatttt cattggtaaa aatttggaag tgttttttag cccagtttct
      301 aactaagttt gccatgtctt catgtctgtt gaatctgtta tctaggcctt catctaatat
      361 attatctaat tggaaatcta aagcgaacat gtgagaaaga gatggtgttg aagggtattg
      421 gtagtttttc ttgattaagt attcatacat tgctaacaaa tcaagatata ctcctctaaa
      481 aggtacttgc ttagctctat cgattgcttt ttgagaaaat gtgcaaatag acattcctgg
      541 tggtaatccc agtgcttttt gtactgatgt tatacaaata tctattccaa tcttatcaac
      601 ctcgactttt attccaccgg ctgaacttac agtatctaca cagtagatta catcttcata
      661 ctttttaaca acttctccaa tttcttctat tggatttctt attccagttg aagtttcatt
      721 gtgagttaca gttattaaat cgtattctcc ggtagaaagc accttatcaa ccatttctgg
      781 cgttgttgcc tctcctaatt caactttaaa tatatccgct gggacattat tagccactgc
      841 cattttgtac catctatcac caaaggatcc acaggaaaat actgctgcct ttttggatgt
      901 acaggaacga atggagcctt ccattaaacc agttccggat gacgtggata aaagtatcgt
      961 gttgtttgta tagaatagtt tttgcatctt ttcacttata ctcttttgga gcatagatgc
     1021 atcttttcct ctatgtccta tcattggtgt agccatcttt tgcaagactt cttctttaac
     1081 atcaatagga ccaggaataa ataatttctt actcattata attcccccct ttttagtttg
     1141 taatatggat agcgttttta ctgtccttat ttttaataac tataatatca agctgaatta
     1201 actatgtcaa cataaaattt attttttata tataatttat tttatatatt ttatgaaaac
     1261 attcattttc caccttttca taagtctgaa ttttctgaat tattctctca aaaaaaatat
     1321 actttttatc tatataaatt atttttttta gtatgtaaat ttgacgctat tacgataaat
     1381 ctttttagta taactaattt atttttatct tgtattttta ttgtattttt aaattttatt
     1441 ttttctaaat ataaaattta tgttttaaaa tgtaaaattt ttatttaatc aaagttcaat
     1501 atattccact ttttctttcg attcttcaaa aaaccattct tcattagaaa aatcaccttc
     1561 tgcaatttgt ccaataggca ttttcatata ctttccagtt gctgtcactg ctatatctcc
     1621 atttggtaga attatttctc ctgtaccttc aaataatttt ctgttttctt tagttattct
     1681 tccaacaact tttatagtag catctgttgg tactggtttc ttatatttca actctaaaga
     1741 tactgttact ccccatattt ggtcatcatt tatacttaca gctcttccaa tagtctcatc
     1801 caatattgca gcagacatac ctccatgaac tctcccagga taactttgat gccaatcctt
     1861 tgtattacaa attgatacaa gctctccatt ttcaagttca taaaaatctg ctttaagtcc
     1921 tagctcattt tgtgttccac aaactaaaca agatttacta ctattttgct tcttcaaaac
     1981 tttatacttt gccaaaaaat ccatctccta accgacatta gtagtcgctt aatattaaat
     2041 aattctaaaa tatattatat aatattaata aaatccctgc aaacttctaa taataaaaat
     2101 aggctacttc aatatgataa gtttaattta aagtattatt ttccaaaaaa taactttatc
     2161 aaaatagaaa ctcaaagtag atataaacct ctttttcgtt attaaaatag taaaaatata
     2221 tttgacttaa tataaaaaag agtgtctcat taactaataa agtttatttt gagacacccc
     2281 tcataaaaca aattatacta caatagattt ttactaattc tacaagttat atatttaaat
     2341 tatattattc aaattaaact ataattctaa atttcattta ctattaattc gcccatttcc
     2401 cttgttccta caacatttcc cacaccatta tagatatcaa tagttctata acctttattg
     2461 agtacacttt gtacagcatc ttcaatacac ttagcttctt cttctaagtt aaaactatgt
     2521 cttaacatca tgcttacaga tagaatagtc gcaattggat ttacaatatc ttttccagct
     2581 atatcaggtg cacttccatg tattggttca tacataccaa aactatcttc tctaagtgat
     2641 gctgacggta acatacctat agaacccgta atcatagatg cttcatcaga tattatatct
     2701 ccaaatatat tattagtcac tattacatca aattggctag ggtcttttac aacttgcata
     2761 gcagcattat caacatacat atgtgacagt tctacatctt caaactcttt agctaagtct
     2821 tccattatac ttctccaaag tcttgaactc tcaagcacat ttgccttatc tacacttata
     2881 agttttttat ttctatttct ggctatttca aaagctctct taccaattct tcttatttca
     2941 ttttcgttat atatttctac atcataagca ttttcgatac catcaatgat ttttcttcca
     3001 cgttctccaa aataaatacc ccctgttaat tcccttacaa caacaaaatc aatgcctttc
     3061 tcaactatat ccgttctaag tggtgaagct tcttttatac tttcatacat tgtagctggt
     3121 cttaaatttg caaataaacc caatgactct cttaatttta aaagaccaga ctctggtctt
     3181 ttatctccct tacatttatc ccactttggt cctccaacag caccaagcaa tacagcttcg
     3241 ttttttcgac aagtttcaac agttttatta ggtagaggtt ctccagtttc atcaatcgcg
     3301 catcctccag ctaatacata ttcacaatcg aatctatgat taaatttaca acaaatttta
     3361 tttagaacct ttataccttc atctataatt tccggtccaa caccatcacc ttttatgact
     3421 gctatattac aattcatact ccactacccc ctatttgctt ttattgagtt aattaagcct
     3481 tcatttaata taatattttg cataaactca ggaaatggtt ctgctttata ttcttttcct
     3541 tttgttatat tttttatcac acctgtagaa aaatctactt ctatattatc cccttcatct
     3601 atgttattgg cagcttcttc acattcaagt ataggaagcc ctatatttat agagtttcta
     3661 aaaaatattc tagcaaaagt agaagcaatc acacaggata ctccactttc ttttattaca
     3721 attggtgcat gttctcttga tgaaccacaa ccaaagtttt tagttgcaac tataatatct
     3781 cctcttttta ccttagaaat aaatttatca tcaatatcct ccatacaatg cgttgctagt
     3841 tctttataat cagctatatt taaatatcta gctggtatta ttacatctgt atctatatta
     3901 tcaccgaatt taaaaacact tccattggca atcataaatt ttacctccct taaattattt
     3961 ctgatggttt tgatattttt ccagttatag ctgatgctgc tgctacagct gggcttgcaa
     4021 gatacacctc tgaatcaaca tgccccattc ttcctacgaa attcctattt gttgttgaaa
     4081 tggatttttc tcctgctgca agtataccca tatgtccccc tagacatgga ccacaagttg
     4141 gtgtagaaac tgctgctcct gcctctataa aagtggtaat ataccctttt tctatagctt
     4201 caagatatac tttttgagtt ccaggaaata tcataactct aactccatct gctacttttt
     4261 tgcctttcat tatctcagct actacttcaa ggtctgatat tcttccattt gtacaagaac
     4321 ctattacaac ttggtctatc tttatatcct tatctatctc atctactgtt ctagtatttt
     4381 caggaagatg aggaaaggct actgtttctt ttagttcggc taaatctatt tcgtatactt
     4441 catcatagac tgcatcttca tctgcttcat atatatttac atcttttgtc atagttgaac
     4501 acttatgtga atttatatat tccatagtct tatcgtctac tggaaaaatt ccattttttg
     4561 ctcctgcttc tattgccata ttacaaatag taaatctatc atccatagat aagtattcta
     4621 ctccatctcc acaaaattcc attgacttgt aaagtgctcc atcaacacct atctccccta
     4681 ttatatgaag tattatatct ttaccactta tccatttatt tggtttattt ttcaaaacaa
     4741 attttattgc tccaggaacc ttaaaccaac attttcctgt agccatacct gctcccatat
     4801 cagttgaacc tacaccagta gaaaatgctc ctaatgctcc atatgtgcaa gtatgagagt
     4861 cagcacctat aattacatct ccagcagtta ctataccttt ttcaggaaga agaacatgct
     4921 ctattcccat atctcctaca tcaaaaaaat ttacaactcc ttttgatttt gcgaaacttc
     4981 ttgtaaattt acattgttct gcactcttta tatctttatt aggtgtaaag tggtctaaaa
     5041 ccatcactac tttagtctta tcataaacat cttcaattcc taatttttca aattctctaa
     5101 tggctactgg tgatgttata tcattaccta aaactacatc taaatctgct tcgattaatt
     5161 gccctttctt aacttcattt aatttagcat gtttggctaa tattttctgc gtcatagtca
     5221 ttcccatttt ttatttcctc ctcaatataa cttttattta ttgcattcat aagtgcatta
     5281 atagctgctg tatttatgtt ttccgatata cttacaccaa aatagacttc attattgtgc
     5341 tctattccta cataagctac ccctcttgaa tgtgaccctt cctctaatgc atgttcccag
     5401 taatatctaa atttataatc tttcatgcca cattgcttta gtgcattatt aaatgaatct
     5461 acaggtccat ttcctatacc aacaatcctt tgttcatttc ccatataact tattcttgca
     5521 gtcatctcaa tcatgttagt atcattagaa tcatcatttt catagtttaa ttcatccatt
     5581 gattttattt tatacttctt aactttataa gggctctcaa cttcaatata ttctttctta
     5641 aacaaattaa atattgcttc actactaagt tcttccccaa ttctatcaga ttccattttg
     5701 actacatttc caaaatcaga atgcatattc ttaggtatca taaatccata atctgtttcc
     5761 attatataaa cagctcctcc ttttccagat tggctattta tccttataat ttctttgtat
     5821 tctcttccaa tatcatgagg gtctattggt aaatatggaa cttcccagta atcattatct
     5881 ctgtttttca ttgctatcat gccttttcta atagcatctt gatgtgaacc tgaaaaagca
     5941 caatgtacaa gattacctgc atatggatgt ctatcatgta ccataagttt tgtacagtct
     6001 tcatatatac ctattatctt atctatattg ctaaaatcta gctctgggtc tattccttgt
     6061 gtataaagat taagtcccac atttactata tccatattcc cagttctttc accatttcca
     6121 aatagtgttc cttcaagtct atcggcacca gccaataatc caagttcact tgcagccgta
     6181 caagttcctc tatcattgtg agtatgcaaa cttagtataa tagaatccct acaacttata
     6241 tttttacaaa accattctat ttggtctgca tatacgtttg gtgttgccat ttcaactgtt
     6301 gatggaagat ttattattac ttttttttga ggagttggtt tccaaacatc tatcactgcc
     6361 tcacatattt caagtgcata atccatctct gttcctgtaa aactctctgg tgaatattca
     6421 aaagtaaatt ctgtttctgg atattttttt acttcttcat taaataattt tgctccttca
     6481 actgctatat ctattatttc ttgtttactc atattaaaaa ccacatctct ttgaagaaca
     6541 gatgtagagt tatataaatg tataattgct tttttacatc cccttattga ttcaaatgtt
     6601 ttttctataa gatgagccct agattgtgta agtacttgta tagttacatc atctggaatc
     6661 atattctcat ctattaattt tcttaaaaat gtatactctg tatttgatgc tgatggaaat
     6721 cctacctcta tttctttaaa tcctgtatca ataagcattt tgaacattct gactttttca
     6781 tttacactca taggtgttgg cagtgactga tttccgtctc ttaaatcgac actacaccaa
     6841 attggagcct taaatatttc attatctggc catttacgat ttactatttg cattttatca
     6901 tattttttat actttccaca cttcatgtta tttccccctt tttctgtttt ttgtattcag
     6961 tatacctcat atcgacgcaa tcctgcacaa ttcataagga taaatgtcaa ttttatcatt
     7021 agaataaaaa aaacctcatc tctaataaaa ttagagacga ggttttgctc gcggtaccac
     7081 tctatttagc tttctaaaaa gctcccttag taatagccaa tacaataatt ataatgacta
     7141 tatttcctat aacgtggaat tactccgatt attctaagat ttaaatctta gaaaacagct
     7201 cctagacaag ttcagaacta tcaactacta aatcacacca tcctttagct ctctgaaagt
     7261 ttcattgttc ttactacttc tattcatcac ttttttaatc atttaaattt tctaaatatt
     7321 ttgatttaat agttattata tacacattaa aatgtattgt caacacaaaa aataattatc
     7381 tcaatttttt atttttgata agcaattcta taaaacatgc taactattga aaacagtatg
     7441 atattatgcc ttaaactttt tcatcttttc atctatgata ttcaataatt ttttttcatc
     7501 ttccaaactc aatgccctta atctaatttt ataattagat tcgtcagtgt atatatttaa
     7561 tatatttttt actacttcta ttttttctat tatcttataa ttaaactttt gactttgttt
     7621 agattttata ctgaatatac attgattatt tattaatatt gaatgattat cgagagtaat
     7681 atatactttt ccctcatatt tatttgaaaa atcacgacct tgtttaaata gaaaaactgc
     7741 tgttattata cataaaatat ataatattgt cgttgaatat ataaaaattg tagctaaaat
     7801 tataagtgct aaaaccatat atatagtcat tcctttttta aaataaccat tgtcataata
     7861 attcatatag ataaacttat ttttactcaa attttttcac tcccaagatt ctaaaaattt
     7921 atatcaaaaa attctataat ttcatcttca tgataattta tgactaattc atctggaaaa
     7981 tctactgctt ctaaaacttt ttctgcattt tcaaattctc ctatagaata acatatatga
     8041 gagtcagtac caagaattac tcttgcacca tatgttttac acaatgtcaa catatgactt
     8101 acattttccc aagtacccgt tctatgagag tttgaactta atgatgaatt atttatttct
     8161 aaaaggatat ttttatcttt agcttttttt actataggtt cataatctaa aggataccta
     8221 ctgtcatctg gatgtccaat tatttttacc ttaggtttat ccataacttt taaaatagca
     8281 tttgtatttt tttcttttgt accagaggct atacaaggtc tatgcaaact tgcgattata
     8341 taatccaaat gtttcaacat atcttcttga acatctaaat taccattata atccattata
     8401 tttccttcta ttcctctaag aatctttacg ccttgcactt cacgtggaag caaatgcaaa
     8461 ttataaaaat agaatggatg tggtcctcct ggcatattag gtccatggtc tgatattcct
     8521 aagtatttta tattcttctt actcgcctct tcgacatttt ccttgaaagt actatgtgca
     8581 tgtccactta ttagagtgtg acaatgtaca tccataatag actttttcat taaatttcct
     8641 cctaatattt tacataaatt cgtgaaaata gctaaagggc tatttcaaaa ctaaagctgt
     8701 cataatagac agtgtaacgt tttaaaacag ccccattttc aattatttta cacttctaaa
     8761 tctttaaatt tatctttaaa taattctcca atacttccta aagattcctc tacttctagg
     8821 tattctgtta tatcctcttc tggctctcta gttgcttctt ttattgaaac caacattctt
     8881 ttagtctttg gtttaaaatc aagaatctta actttaacct catctccaat attaacaaca
     8941 ttagtaactt tagccactct agtatcactc aattcagata ttggtaaata cgcatctaca
     9001 ccttctttaa tttgaacaaa agcccctttt tctattattc taagaacttt agcattgaca
     9061 acatcatcaa tttgtacttc ttttgctatt aaatcccaag ggtcattatt tatgtctttt
     9121 aatgccaagg caattttttt agtctcttta tttacatcca acacataaac ttctacttct
     9181 tgtccctctg aaacaacatc ttcaacactt tcaactcttg tccaagctaa attatttata
     9241 tgtgctaatc cttcaatccc accaatatcc acaaatgcac cataaggcat tatctttgtc
     9301 accttaccat ctcttttttg tccaacttca agagaattaa ataagtcttc tttagctgct
     9361 ttgatacgag ctttttcttc ttctctttct tgcttaattc ttgctctttc agcttctttt
     9421 tctgccttaa tttgagctct tctttcttct ctctctttat ttatacgctc ttgtaataca
     9481 tctctatgag atgctacaag tctatttttt ctaacatcca attcttttat ataaacttct
     9541 aagttaagac caacaaattt agatgtatct gtaataaatt ttgtatcaag ttgagaaatt
     9601 ggtataaaaa atgtatatgt attgtaatta gcaaatacac ctttatctat attcttttca
     9661 acatttacag ttattattct atgttcatca taagcctttt gtaactcggc aaaatcattt
     9721 cttttgtcaa gttgtaattt agataaagtt attgtaccat ctttttgaga tacttttgtt
     9781 attacagcag ttatttcatc acctatgtgg tatatatctt ctatatattg atttttttct
     9841 atgttcaatt cacttatagg tattattcca tcaaacccat agtctaatcc taattgtact
     9901 tcatcatttc tcactgcagt tatttttcca gttgtcaatt ctccaacttt cactttgctg
     9961 aatacttgtt cttgctggtc aagtaattct tgcattgtta aatcattttc cattataaac
    10021 atcctttcct cttattgatt atcatatctg taaatattat accattaata ttgcaaatac
    10081 ttacattttt cttactataa tttttaaaat aaattcaact tcatatattt atacattat
//
LOCUS       DAEQAF010000118        10058 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.122, whole genome shotgun sequence.
ACCESSION   DAEQAF010000118 DAEQAF010000000
VERSION     DAEQAF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10058
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.122"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            200..1081
                     /locus_tag="KRN00_003220"
     CDS             200..1081
                     /locus_tag="KRN00_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBH1829066.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESVKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            1272..1439
                     /locus_tag="KRN00_003221"
                     /pseudo
     CDS             1272..1439
                     /locus_tag="KRN00_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418025.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(1699..4266)
                     /locus_tag="KRN00_003222"
     CDS             complement(1699..4266)
                     /locus_tag="KRN00_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBH1829067.1"
                     /translation="MIYYVLPLEHKQATIEIVGGKGMSLSKLLTAGIPVPDGFHVTTD
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKMAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     LLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPLHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSPAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     APQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(4269..4874)
                     /locus_tag="KRN00_003223"
     CDS             complement(4269..4874)
                     /locus_tag="KRN00_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1829068.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTDTALVT
                     RLLINSMLSISYTSRPLDSSEKMLDETMNIFLHGIMNDGGE"
     gene            complement(5248..6708)
                     /locus_tag="KRN00_003224"
     CDS             complement(5248..6708)
                     /locus_tag="KRN00_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBH1829069.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRANIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEAVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            7041..7619
                     /locus_tag="KRN00_003225"
     CDS             7041..7619
                     /locus_tag="KRN00_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1829070.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKALKMLYRLYDKN
                     PFLYSPTNTDYITLLNKIPKEMLSQLEYSNVQSFYSLIERHNLKLKIEKEKAFGVCNA
                     LLSSLLLKEDIGYDYIEVFDFMVDNLVEHILE"
     gene            7670..7903
                     /locus_tag="KRN00_003226"
     CDS             7670..7903
                     /locus_tag="KRN00_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829071.1"
                     /translation="MIELIQRLNDIIYKINDKLNIHTKLVDPNSELMPLYSMLSIIVS
                     IFLIILGIKVRKKFLIIIAIISIIINILIILDR"
     gene            7912..9162
                     /locus_tag="KRN00_003227"
     CDS             7912..9162
                     /locus_tag="KRN00_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1829072.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            9323..9892
                     /locus_tag="KRN00_003228"
     CDS             9323..9892
                     /locus_tag="KRN00_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1829073.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3343 a         1734 c         1497 g         3484 t
ORIGIN      
        1 tttaattttt attatttgta cttatttaaa gtttcatcta attataaatt ggacaatttt
       61 tatgttgatt ttattcatac aaattaaagt aacttataaa atctccacaa taaaaaacat
      121 tttttattca ctaaactgct ccatcattgg tttagcaata aatatatttt ttaggtcttt
      181 aatgtcaata gtgttaaata tgccagcata tttatttgat agtaattcta ttgcaaatat
      241 ttacagagta tttcctatat catttagctt tatagttaca ggactatatt tcagttataa
      301 aaataataaa aataataaga ttaactttga ggcagtttta gaggacaaaa aaaacttaat
      361 tttcttattg agccttatgt ttggaatgta cttgtatcta tgtttgagtt tgtcaatata
      421 ctatactgtt ggaaatgtat tgattttaaa attatatgga atcaagtctg ccataatagt
      481 tttggtaggt aactatattg cagaaagata tagctttaga attactcaaa taaaaggtta
      541 tgatattaaa aatcaaatag aatatgtaga aagtgtaaag acagagtatg aaattaataa
      601 attgaatgat attgtatata cagatttact gacaggcttc tacaatagac cttttgtaaa
      661 tcaaaaacta tcagagtgga catcaaatca ctacaaattt accttatgtt ttactgattt
      721 aaatagctta aaacctgtaa atgataaatt tggacaccaa tttggtgata aatacatatc
      781 cactactgct caaataataa aaaaacttat aaatgtagaa aattccttac tatttagata
      841 tggtggagat gaatttttat tccttttaca gaatacaagt tgtgtagaag cagaaaaaat
      901 aatgattaat ataaattatg aattatcaaa attaagtaat actgacgagt atccttatgc
      961 tctttccata agctatggat tagttgagtg ggatggaata tccgacattg aaactttaat
     1021 atcaaaggca gattctttga tgtatgaaaa taagcttaaa aataaatcta ctttaaacta
     1081 gctagttcag atattctaca aaagatatgt tataagagag tactaagaat gtcaaaatat
     1141 atagattttg caaatattga atacagttta ctaatgaatg cactggatgt aagtgttagt
     1201 aaacacctat tagatgaaca ctttactgtt gtttgggcta atgaccgtta ttatgaaatg
     1261 ttcggctata cctagctaaa aagttaaaaa tgaccactgt agccgaggga atagagacca
     1321 gttttcaaaa agatttcttg caagaaatag actgtgatat gttacaagga tacgtgttct
     1381 ctagaccttt accaataaaa gactttgaaa aacttatgtt tcaaaactcc tccaattaac
     1441 aatataaaat tgcttattat aagtgatatt attgtatcaa caaataaagg aattgtctca
     1501 aaattgattt tttctaatca aatttttatt ttgagacatt ctcatttttt tgcataagaa
     1561 aatacccacc aagctacggt ttttcttacc gctgttcggt gggtattagt agtattatga
     1621 aatctgaaaa ctttaagtat tactacttcc gctaacgcaa tcacaaaggt cgaaagcttc
     1681 aaagcgaaaa taggcttttt actcatcaaa cgtcaccgta cctgccaacc cgtccaccgt
     1741 tatcatttgt ccgctcttaa tagttcgtgt ggcaatgtgt gtagccataa cggctgggat
     1801 gccatattca cgtgcgacaa tgcttgaatg gctaagagga ccaccaatgt ccgttacaat
     1861 cgcacttgca gatgaaaata atggtgtcca tgctggagtt gtggtaactg caaccaaaac
     1921 acttccaggt tgaaagcttt caaaatctgc tggactattc agtacacaag ctggagccgt
     1981 cacaacacca gtactggtac caatgcccgt caacacaatt ttcccatctt tctgcttctg
     2041 tggtgcttgt gatatagttt ttttgttttt ctctggcaac ttggatggtg acacataacc
     2101 catgtatttt ttaagttcag cttttcgaac aggtattatc ccgttcatat cagatagaga
     2161 cttgttttta tccaactgct ctataagtac ctccaattcc gattttgtga gccaataaat
     2221 atcatctaaa tgtgaaatag ctcctcctcg tatgaatcgt tctgaaattt cctgaaacat
     2281 acaacgaatc agaggatgtc ccattcccat caaataaata gcattttcac gcataggaga
     2341 ggtttcctgt gcccaatgga gcaacttaaa aaatagtttt ttacgcaatc cacctatgtg
     2401 ttgtaaaatc tcttcttctg catgttttct acgcttttca aacgtggtct ggcgtaaaaa
     2461 aggactttcc ccttttcctt ccacaaatgt ttttacggat tcaaaagttg gtgtaagtgt
     2521 ttcctgcggt gtggaatgcg caaaatcaaa ctcataagcg gtacgaccaa actctttaaa
     2581 gtacttattg attcgatttt tccattctat ccatacttcc tgtgaaactc caacaggcac
     2641 aactgaagac atgaaatctt ctgctatctt tattgcagga ctgttttgca gataaaggtt
     2701 gatgctgtta ttttgcttta cccattctga aataccccac aactcctttt ccgattgcag
     2761 aacaatcgta tcaaacccaa gcaggaaaac ggaagtatcc gttataccag cacgtcgaac
     2821 tgctccttga aataattttg taaataatgt ttcactgata gaagcagcag gcaatgtaag
     2881 ctgaatcctt gtgaaataaa tacatgcggc ataaaatatt gtctgaatac cctccataat
     2941 ttgatgggcg ttcatagtat gcaggggctt ttcttcccat tgtttaatag catcctcata
     3001 tccttttcgt gccgtttccc agcgtgcaac gctgttcata agtgtcctac gtaaagagcg
     3061 tggggaaagg gatttgatag caatcaaaag tggctttgat ttagcagaaa gataaacata
     3121 tccattaata accgtatatg ccccgttttt tggtaataat tttttcgcac ttttaccaaa
     3181 catatctatc cataaaagct ctgatgcacg gtttacgatt tcaagaccaa gcgtagcgaa
     3241 caaaggtgta acaggatttg gcaagtgttc tgccaaactt ccctttgtgt atacaacatc
     3301 ctgttctggc aatacccatt ctggtggcag aacagtaatt ggacgagcct gaacaatgta
     3361 caatttatct ttttccagtg cccactctac atccataggc atttgataat acttctcaat
     3421 tttctttcca agctgtatca gttgcattac ctgattacga gtaagagcat atttttttct
     3481 caacctttca ggaaccatgg tttcttctgt tccttctgaa gtacgaaccg tcataatctc
     3541 tttatttgcc acttcatacg atataattcg ttcggaatcc ttatccacca cgattgtatc
     3601 gggtgtaact aagctagaaa ccaccgcttc accaagcccc catgcagcgt taataatcat
     3661 ttcgctacgt ctaccattga ttgggtttaa cgtaaacata ataccagatg aatcggaaaa
     3721 tgcaagcttt tgtactacaa cagcaagtgc gacaatctcg tgctttatat tattcttcac
     3781 acgataagca atagcacgag ctgtccataa ggaagcccag catctcttta cagcgtcaat
     3841 aactttatct tcaccttgta tgttaagata agtttcctgc tgacctgcaa aagaagcgtc
     3901 aggtaaatct tcagcagtcg cagacgaacg gacagccacc gatatgttcc ctaatccggc
     3961 ataagccatt ttaattgcgt ccgacacttc ctgtggcatt tctccattat ggaaaagctc
     4021 ccctattttc ttagatacat cttcaagttg gctggtatta ttggaatcaa taccatctag
     4081 cagtttatta attcgagact gaatatggtt cgtctcaaca aaaatctggt atgaatcagt
     4141 cgtaacatga aaaccgtctg gcacagggat acctgctgtc aatagttttg ataaagacat
     4201 cccttttcca ccaacaattt caatggttgc ttgtttatgt tccagtggca agacataata
     4261 aatcataatc attcacctcc atcattcata attccgtgca gaaatatatt cattgtttca
     4321 tccaacattt tttccgaact atccaatggt cgtgacgtgt agctgattga taacatggag
     4381 ttaattaaca aacgtgtcac aagagcggta tccgttttgc gaaagatgcc tgtggtcaca
     4441 ccattatcaa ttaccgattt tataatatct tgatatgcat aacgagcatc tttaagtctc
     4501 tttcgatact cttcttctaa ataatcagat tctgtattta accacatcag tacagttcta
     4561 tactgctctg gaaatctaag atgattaagc atgatttttc taaggcactg ttgtggtgaa
     4621 ggttcaccat caataatcct atgaacttgt tggatagttt tttctatttc tttctcaact
     4681 gcatatacaa caatctcgtc tttcgttttg aaaaaatcgt atagacttga ctttcccatg
     4741 ttggctaaaa ctgcaatttc tctcattgat gttttttgga atccattttc agccatgaga
     4801 ctcaaagcaa cagcaactat tttttctcgg cgttctgctt gttgttcggg tgtaagcaca
     4861 attccttttg gcatagggcg atacctcctt ttagcgacca ctggtcgttt cttttttatt
     4921 tatcatacag cgaccaacgg tcacttgtca aggttaattt ttttcattgt atatggtact
     4981 cgagataaaa atgttcattt tagaaattgc tctatttaag tagaaatagg cttcatcatt
     5041 agaaagcaag actataaatt tgagatattt atcatgttca aatttcatca atatcaaagt
     5101 ttaagatatt aataaaaaaa gaattactaa gaaataacat ataaagattc aaaaaaggag
     5161 ttgaacttaa aatttaatta caaaaaatca aatttaagac aactccttta ttctttatct
     5221 ctactattct ttatctctat ttatttatta caactcccta acatttacca ctactgcctt
     5281 aggtctagtc atagcctcaa ttgaatactt aacaccttga gttcccatac cagatgcctt
     5341 tacacctaaa aatgggaagt ggtctggacc tctttcagtc ttattattta tttgaacagt
     5401 accaacttca agtttatcag ctatataaaa tgccttatca atatcacttg taaatactga
     5461 tgattgaagc ccatactctg attgattagc aatttcaatt gcttgattta tatctttaac
     5521 tcttataatt ggaagtactg gaccaaatgg ttcttcccaa gcaattttca tatcaacatt
     5581 tacattatct aacaatgttg gatagaataa attatttttt ctaacattgc ctgttattaa
     5641 ctttgctcct ttatgtaatg catcatcaac caacccttga acaaaatcag ttgctttatt
     5701 atctataaga ggagtgataa ctgcttcatc cattggattt ccaattgtca acttctctac
     5761 caatggcttt atttttccga ctaatttatc cgccacactc tcttgtacta aaattctctt
     5821 tactgccgta catctttgtc ctgaatatga atacgctcca gatactatat tcttagctgc
     5881 aaaatctaag tctgcatctt ctaatactat agccgcatct tttccaccaa gctccaataa
     5941 taatggtacc attccagata ttttagatat atgctgacca acttcagtac taccagtaaa
     6001 gttaataaaa ttaattcctt tatgcgttac aacataatct cctatctcac tacccctacc
     6061 tgtaatagta ttaagtactc catctggtat cccagctttt ctcataattt ctaccacatg
     6121 aagtgcgcta atagcccctt gtgtagcagg ttttaatacg actgcatttc caccaataag
     6181 tgctggagca atctttgaca ttgatagatt tacaggataa ttaaaaggag atatagctaa
     6241 aacagtacct aatggaaccc ttgaaacata agacatttta tttcttgttc caccagggaa
     6301 attatctcca ctaatggctt caccctccat attttttccc acatcagctg tgtatcttaa
     6361 aaaatctgct gttctctcaa cttctgccct tgcagatttt atgtctttag ctatttcaag
     6421 taccagtata ttagctatct catctatatt ttctaacaat aaatcagcag ccttatgaaa
     6481 tatattggct ctcttgtata caggcatttc agcccatact tttatactct cttttgtgtt
     6541 ttttataacc tcatctacct catgttttgt catagattgt actttcccaa caagagaatt
     6601 atctattggt gagtaaattt ctattggctt tctcgaatta gattctaccc attttccatt
     6661 tattaaattt ttatatacat tttcttttgt tttaagttca ttaaacatat ttttattcct
     6721 ctctctgata taactttgtg tatttaaatt atagccattt attcgttatg taaacatttc
     6781 tttttttcat aaacgtttac ctataaaaaa aattttaagt taacgttttt ctacattctt
     6841 ctattttaat aacatactcg ctccaaatct atataggtca cactttaata ctaatatacc
     6901 aatatactaa tatatcaata taccaatatt ataaacataa atcacttgac aaatttataa
     6961 gtagacaata ttatatatct atgacttaaa atatttttaa agtcatagat atcatatata
     7021 gatagaaagg attgataaac atggctaaaa gttttacaga aatagaaaaa gacaatataa
     7081 gaaaaagact aatttcagaa tgtgaaatca actggtctaa atatggatac aaaaaaacta
     7141 atattgatga actttgttca aaatcaggaa ttgcaaaggg ttcattctac acattctttg
     7201 attcaaaaga aaagttattt tttgaagtat taaatggaat ccaaaacaga cttatatcat
     7261 cagtagatga aattttaagt aacatgcctc caaaagaagg ctttgcaaaa gccttaaaga
     7321 tgttgtatcg attatatgat aaaaacccat tcttatattc accaactaat actgattaca
     7381 tcactttatt gaataagata cctaaagaga tgctttcaca acttgaatac agcaatgtac
     7441 aaagttttta tagcttaatt gaaagacata atctcaagtt aaaaatagag aaagaaaaag
     7501 cctttggtgt ttgcaatgcc ctactgtcaa gcctattgct aaaagaagat attggatatg
     7561 actacattga agtatttgat tttatggtag acaatcttgt agaacacata cttgagtaat
     7621 aatttaaaat aaattttcta aacatttctt tataactagg aggagtaata tgattgaatt
     7681 aatacaaaga ctaaatgata ttatttacaa aataaatgat aaactaaata tccacacaaa
     7741 acttgtagac cctaacagtg agctcatgcc actttactct atgttatcta taatcgtttc
     7801 tatatttcta ataatattag gtattaaagt aagaaaaaaa ttccttataa taattgctat
     7861 tatatcaatt attataaata ttttaataat cttagatagg taggtacata tatggtaaaa
     7921 tcctcgaaca cttttaataa aaacttcaac ttgatgatat taggtcaaat aatctcattg
     7981 tttggtgcat caatacttaa atttgcttta tctttataca tacttgatat aactggtaaa
     8041 gcagaaatat ttgctactat actagcagta tcttcaatcc caattatagt attctcccct
     8101 attggtggag ctattgcaga tatattcaac agaagaaact taatggttat ttttgatttt
     8161 tcaagtagtc ttacagtact aatcttagca gtattcttat tcaacaataa tggttcaata
     8221 ttacttgtag gaattattat gaccatatta tcagtcataa gcacaatgta tcaaccaact
     8281 gttcagtcaa gtacacccct tttagttgat aatgagcatt taatgaatgc aaatggtatt
     8341 gtagctggag ttgcatctct tacaaatatt gcaggacctg tattaggagg tgtcttgtat
     8401 ggtgtgattg gaattaatgc aattatagtt atcagttgtg taagtttctt tctatctgca
     8461 attatggaga tatttataca gattcctttt atcaaacaag agcaaaacag caacattata
     8521 aaaactatat ttactgatat aaaggatggt attgttcata tatgtaaaga aaatagattt
     8581 atactaaaaa tacttttttt agctatagca ataaacttat ttttaagctc tatgttaata
     8641 gttggtatcc cctatatagt aaaaatcact atgggagcta gtaacttctt atatggtcta
     8701 gcagaaggag caatttcttt tagttcactg gtagctgctg ttagtattgg tattttctca
     8761 aaacatctaa aaatcactaa tttgcacatt tcctttatta tatgtgcagt tatgttcata
     8821 ccaatggcgg tttcagtata tccatttata ttaaacacag gatttccagt tccattttta
     8881 atctttatag tatcatctat gctaatattt tttacaacga ctcttatctc aatatatgtt
     8941 ataacagtca cacaattaaa aactccaaat gaactcttag gaaaagtaat gtcaattctt
     9001 tttgcaggaa cagcaattgc aatgcccctt ggtcaggtta tgtatggtaa actttttgat
     9061 ttattatcag atagagtgta catcattata ctaggagttg gatttattac actgcttata
     9121 gcatttgtat caaagataac attgaggaac gaaaatcttt agatacaaag aatttagata
     9181 taaagattta attttcacta atttctgaat ttaaatgcaa aattgtgtat cagtatgttg
     9241 acgttttaga aattgattga tataatcaat ggaaaataaa ctttataaaa attcaaaata
     9301 ttcagctaga ggagtgataa aaatgagtta catgccaact ttagaacaag catgggaaat
     9361 attaagaaaa tacaataagg aagaatttca tataagacat gctcaaattg tatctggagt
     9421 tatgagatac tatgcaaagg agtacgaccc tgaaagagta gaattttggg aaatagttgg
     9481 acttttacat gatttagatt ttgaaatgta tcctgatgaa cattgtgtta aacaaagaga
     9541 attaatgaca gagcttgatt tagataaatc aataatcgat tctacaataa gtcatggata
     9601 tggattaact ggttcagatg ttaaaccaga gcaatttatg gagaaagtat tatttgctgt
     9661 ggatgaactt actggtttaa ttggtgctgc tgcaataatg cgtccttcaa agagcgtttc
     9721 tgatttagaa ttaaaatctg ttaagaagaa atttaaagat aaatcatttg ctgctggctg
     9781 ttctcgagac gttataagaa gtggtgcaga aatgcttgga tgggaacttg ataagcttat
     9841 ccaaacaact atagaagcta tgagaagctt gattccagag atggcaatat agctcctcca
     9901 tacatatacc atagaagtta catctttaaa gagcatttct ctttttgatg caacttcttt
     9961 ttatattttg tagaataaaa agtttaatat tttaaactca ctatataatc tataataaat
    10021 actataaata atataatgta taatagttat aaactttc
//
LOCUS       DAEQAF010000119        10025 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.123, whole genome shotgun sequence.
ACCESSION   DAEQAF010000119 DAEQAF010000000
VERSION     DAEQAF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10025
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.123"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            215..1690
                     /locus_tag="KRN00_003229"
     CDS             215..1690
                     /locus_tag="KRN00_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1829074.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISLGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            1777..2190
                     /gene="speD"
                     /locus_tag="KRN00_003230"
     CDS             1777..2190
                     /gene="speD"
                     /locus_tag="KRN00_003230"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBH1829075.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            2220..3071
                     /gene="speE"
                     /locus_tag="KRN00_003231"
     CDS             2220..3071
                     /gene="speE"
                     /locus_tag="KRN00_003231"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBH1829076.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            3061..3939
                     /gene="speB"
                     /locus_tag="KRN00_003232"
     CDS             3061..3939
                     /gene="speB"
                     /locus_tag="KRN00_003232"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBH1829077.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(4120..4320)
                     /locus_tag="KRN00_003233"
     CDS             complement(4120..4320)
                     /locus_tag="KRN00_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1829078.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            4786..6276
                     /locus_tag="KRN00_003234"
     CDS             4786..6276
                     /locus_tag="KRN00_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1829079.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            6556..8052
                     /locus_tag="KRN00_003235"
     CDS             6556..8052
                     /locus_tag="KRN00_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1829080.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            8186..9112
                     /locus_tag="KRN00_003236"
     CDS             8186..9112
                     /locus_tag="KRN00_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1829081.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINSAEINIHPASKSKYESSNDYSTITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            9230..9421
                     /locus_tag="KRN00_003237"
     CDS             9230..9421
                     /locus_tag="KRN00_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829082.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            9644..9994
                     /locus_tag="KRN00_003238"
     CDS             9644..9994
                     /locus_tag="KRN00_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829083.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMSFSKQEV
                     YQGIEDIRKVLNLE"
BASE COUNT         4005 a         1045 c         1812 g         3163 t
ORIGIN      
        1 aattaatata aacaacaaaa aattaaaaag tttataaata ttgatatagc taatgtatat
       61 gtttttgagt aacttcaaaa aaacacttgt aaaaatgctg agatgttaat ataataaata
      121 tcatgagttt aataaaagta aaaataaaaa atagaaataa taaataataa atattaaaaa
      181 tatttgaata tagagaggag atgaatttga aatcatggat agcgagtttg caaatgcagt
      241 tgaattaagc tatgagtgtg ctccattatt agagtcgtta aaggaatact cagagaaaga
      301 tatagcttgt tttgatgtgc ctggacatgt aaaaaataga ggtgtagcta tattaaataa
      361 atatctaggt gaaagtctca tgaaaatgga tataaattca tcaccaacta tggataatgt
      421 atctgcgcca aatgggatta taaaaaatgc acaagatttg ctagcacaag catatatggc
      481 tgatgaggca ttctttataa cgaatggcac aactcaagca atacatgcaa tgattttgag
      541 tgttataaaa ccaggtgaaa aagtattact tccaagaaat atacataaat cagtaataaa
      601 tgcgttaata ctttgtggag ggataccaat atttatacaa ccagaatttg atgaaaaact
      661 aggtataagt ttaaatatta ctcttgaaaa agttagaaca gagatagaaa aagattgtaa
      721 tataaaagca ttatttttcc ttaatccaac ttactatgga gtttgtgcag accttgagag
      781 tattatagaa ctatgccata aaaataatgt tttagtgtta gttgatgaag ctcatggtgc
      841 acattttcca tttcatttag atttacctcc ttctgcaata agtttaggag ctgacatggt
      901 agctgtaagt atacataaaa ctggaggggc attgacacaa tcttcagcac tcttattgaa
      961 tagagataat gtaagttttg aaaaggttct tcaatcaatt aatatgctac aatcaacatc
     1021 agcatcctat ttgcttatgg caagtataga tggtgctaga gttaatctag ttgagaatgg
     1081 tgaaaagcaa ctgtcaaaag cattaaatct atctaggtat gcaaaatcta aattgaacaa
     1141 aattgatgga ataaaagttt tatctacaga aatattgaaa caaaaaggtg ttaaatttat
     1201 agatgaaaca aaattgtgta taaatgtaaa agaattaaat ttgactggat ttgaagtata
     1261 cgatttatta tataaaaatt tttcaattca agtagaattg ggagattcat ataatatact
     1321 ggcacttgtg tccattggaa caaataaatc agatatagat agattagtaa aagcactttc
     1381 tataattgca aagatttata gaaaagaatc aacattaaat gaatttaata tggttcaaat
     1441 aaatccaatt attaaactta atccaagaga agctttttat gcaccaaagg aaagtgtaga
     1501 aatcaattca tgtatagata gaatttgtgg agaatcaata atggcatatc caccaggtat
     1561 accgattatt gctccaggag aattgataac agaagaaatt atggagtata ttattttctt
     1621 aaaaaatagc aatgcgtatc ttacagatgt acaagataaa aacttagata gaatactagt
     1681 aataaaataa attaccttat tttgtaaggg caagtgtttg ttaagtagag tttatcaaat
     1741 agaacttatt aaaagtataa aggagttggg gttgaaatga aatttgaaac actaggaaga
     1801 catatactag tagaatacta taattgtgat gaaaacgtac ttaaagaccc acgtcttata
     1861 gaaaatttta tgaatgattc agcattaaat gcaaaagcga caattgtgga ttctgtattc
     1921 caccatttta atccttgggg ggtttcagga gctgttataa ttgctgaatc tcatttgaca
     1981 atacatacat ggcctgaata tggttatgca gcagcggatt tttttacttg tggtgatata
     2041 gacccatgga aaagttttga attattagag caacttttaa agtctgaaag aagcgagtct
     2101 acagaaattc caagaggctt aactacaaaa attaaaaaat attcaaaaaa agatttaggt
     2161 aagattactc ataaaccaga agcagtataa aacatacaag agaaagtgag gattattata
     2221 tggaactttg gtatacagaa gaatggacag aaaatgtaag attttctata aaagtaaata
     2281 aacatctatt tgaaggaaag tctcaatttc aaaggataga tgtgtttgat agtgatgaat
     2341 ttggaaaatt tctaacaata gatggattaa tgatggtaac atataaagat gaatttatat
     2401 accatgagat gataactcat gttcctatgg ctacaaattt aaacataaag aaagtattag
     2461 tcataggtgg aggtgatgga ggtacagtaa gagaattaag ccgttatcct caaatagaaa
     2521 agattgacat ggttgaaata gataaaatgg ttgtagatgt atctaaggag tatatggata
     2581 tatgctcatg taaattagat gataaaagag tgagtttata ttttgaagat ggtgttaatt
     2641 ttgttaagtg tgcacatgat aaatcatatg acctgataat agtagattca actgacccaa
     2701 taggaccagg cgaagggctt ttctcaactg atttttataa ggattgttat agaatactga
     2761 ctgatgatgg aattttagta aatcaaagtg aaagtccgta ttttgacttt aatgctaaag
     2821 agatgaaaag agctaataaa aaattaaaac agatatttcc aatatcagaa gtttatcaag
     2881 cacatatacc aacatatcca tctggtcact ggttgtttgg atttgcttca aaaaaactta
     2941 atccagtaaa aaatcaagat agaaatggat gggagaaatt aagtttaaaa actaaatatt
     3001 ataatagtga tatacattta ggttcgttta tgttacctca atatgtgaag gagatgctag
     3061 atgaagaata atttctatca tatgaacact tttatgagta tggacaaaaa ttatgaagaa
     3121 tctaatctta tagtatttgg tgttggattt gatggaacta cttctaacag acctggggct
     3181 agatttgcaa gtagctctat gagaaaagaa ttttacggtc ttgagacata tagtcctttt
     3241 ttagatttgg atttagagga ttataatata tgtgattatg gagatttaga aattagtgtt
     3301 ggaagtacag aacaagtctt aaaagaaatc tatcaagaga catataagat tgttagagat
     3361 tcaaaggtac cctttatgat tggaggagag catttagtta cattaccagc ctttaaagca
     3421 gtacatgaaa agtataatga tatatatgta attcattttg atgcccatac tgatttgagg
     3481 gaagaatata ataatagtaa aaattctcat gcaacagtaa ttaaaagaat atgggatatt
     3541 gtaggtgata ataaaatatt tcaatttggt ataaggtctg ggacaaaaga agaatttaaa
     3601 tttgctacag aagaaaaaca cacatacatg gaaataggag gaatagatac gtttgaaaat
     3661 atagttaata tgctaaatgg aaagaatatt tatctaacta tagatttaga tgtattggat
     3721 gcatctgtgt ttccaggaac aggtacacca gaacctggtg gtgtaaatta tagagagttt
     3781 caagagattt ttaagattat aaaaaactct aatataaata tagttggttg tgacattgta
     3841 gagttaagcc ctgattacga tacaacaggt gtatcgacag ttatagcttg taaaatctta
     3901 agagagttat gcttaataat atctgataaa attaaataga gtattttata taaatagtat
     3961 atatatataa tataagaagt tattttaaaa aagttagttt aagtttgacg cttttctaaa
     4021 gtaacttctt atttttgtaa ttaaaaataa atataataaa caacaaaaaa gagccctcga
     4081 tagctccttt tctaaaatat atatatttaa attaaataat tatattctat ttacgttttc
     4141 agcttgaggt cctctattac cttgagttat atcaaagcta accttttcgc cttcttctaa
     4201 agttttgtat ccatcatttt gtatagctga gaaatgtacg aaaacatcat cttctccctc
     4261 tacagatatg aacccaaatc ctttttcatt gttaaaccat tttactattc cgtttttcat
     4321 tataagaaaa cctccgcatt attaaaaata caaactaaaa aaataagtct gttctattaa
     4381 tataacataa attttaaata aaagcaaata aaatttttaa aaaaattaat tacttttaga
     4441 atttaataaa aattgttaaa ttatacagtg agaagtattg taaaatttga cgaaaatgta
     4501 aatgtagata ataaatttaa tatcaaaaaa tgtaacaaaa aggtatgtaa gtaaaaagta
     4561 aaattaaaat atataataaa aaatattata tattagattg aaaagtaaaa ataaaaatag
     4621 tgaaatttca gaaatatcaa taatattata taataaaaca aaaaaacatt atatatattc
     4681 gataaaataa aatttaaaca tataatattt tatgtatata ttaataaaag gacatattgt
     4741 gttataatgg tatcgtataa aatcatttac gggggtggta ttaaaatgtt tcaatttgaa
     4801 acacaaatac acaaattaag acatgatgtt ttaactgcaa tagctagact tggaaaagaa
     4861 gataacctta ccagagaagc aatggataat attcagtatg aaataataaa aggtgagaaa
     4921 cctacataca gatgctgtgt ttataaagaa agagctataa tatctgagag agtaaatgta
     4981 agtatggggt tacaaccagg tcaagataag atagatttag atacaatgga tatagaagaa
     5041 gatgaacaaa ttatatatat tttggaagct gcatgtgaca gttgtccaat aaatgaattt
     5101 acagtaacag atatttgtag aggatgtcta gcacatagat gtaaagaagc ttgtaaattt
     5161 ggagctataa cacatgtcgg aggaatggcc tatataaatc atgaattatg taaggcttgt
     5221 ggaatgtgta aaaaagcttg tcaatatgat gccatctcag aggttgttag accatgtaag
     5281 agtgtttgtc caactaatgc cttaggattt gatagagaaa atatgaaagc tatgatacat
     5341 gaggataaat gtttaaactg tggagcatgt atgtcagcat gtccatttgg agcaatatct
     5401 gataagagtt tgatagctcc tgtagctaga aagttagttc aaaaagagaa aatgtatgcg
     5461 gtggtagctc cagctataac aggtcaagtt gaagcaaatg ttacatatgg tcaaataaaa
     5521 aatgctataa aatcactagg atttgttgat gtattagaag cagcttgtgg agcagatgca
     5581 gttacagttc atgaaagctt agaatttgct gaaagaatgg aaaagggaga agcttttatg
     5641 acaaattctt gttgtccagg atttgttggt tatatagaaa aaacataccc aaatcatgta
     5701 ggaaaaatat cttctacagt gtctcctatg atagctagtg gtagatttat aaaaagtcat
     5761 gaaccagatg ctaaagttgt attcatagga ccatgtacag ccaaaaagag tgaggcagct
     5821 aagaaagaat taaaaggagc tgttgattat gtacttactt ttgaagaaat aatggcatta
     5881 tttgaggcat ttgatataga cttggctaag tgttcaaatg aagatataga tgacgcatca
     5941 atttttggaa gaggttttgg agctgctggt ggtcttacaa aagctataga aaattatctt
     6001 gctgaaaaag gtattggtgt taattttgaa cctgtaaaga tttctggttc aagagaaatc
     6061 aagaaaacta tgactatggc taatttagga aagctagaag gtaattttat agaaggaatg
     6121 atgtgtgaag gtggttgtat aaatggttct ggtaaattct tatcaggtgc aaaggttaaa
     6181 gccacttttg atagaaaaaa ttctcaatca actaagaaaa gtgtcttagc aaatacaaag
     6241 ataaaagatt ttagtaatat aaatttagaa aaataaagat aatacaaagc aacaaaaata
     6301 catattgtta atagagttgt tctaagttga ggtttaactt ttggacaact ctatttttat
     6361 ttatatattt aattattgaa cgactaaaat aaaaattata tacacttaaa ataaaaatta
     6421 catatataat attttgtata taacttaaca aagtatatgc ctatgttata ataatttata
     6481 gaaataaata aaaaatacaa tatacataat agtagaaata tagcaaaaag gtgtgattta
     6541 tagggaggat tacttatgtt tgaatttgaa acgcaactaa aaaggttaaa acatgaagtt
     6601 ttaacagcag tagcaagact atctattgaa gaaaatttaa caaaagaaaa tatagaaaaa
     6661 attccatatg aaataattaa aggagaaaag gcgagatata gatgttgtgt ttataaagag
     6721 agagaagtag ttcttgaaag ggcgcaactt gcattaagtt taactccaaa tagtaaatat
     6781 ggagatataa atccagattc agttagtttg gacacagatg agcaaattat atatatagtt
     6841 gaagcagcat gtgatagatg tccaataaat gaatttacag ttacagagct ttgtagaggg
     6901 tgtttggctc atagatgtaa ggaagcatgt aaatttgggg caatttctta tataaatggg
     6961 agagcatata taaatcatga tttatgtaag gcttgtggaa tgtgcaaaag ttcatgtcaa
     7021 tatgatgcta tatcagaagt tgtaagacct tgtaaaagcg tttgtccaac aggagctttg
     7081 gattttaata gaaacactat gaaagcaatg atacatgaag ataattgtat aaattgtgga
     7141 gcatgtatgt cagcatgtcc ttttggagca atatctgata agagtttgat agcacctgtt
     7201 gcaaaaaaac ttgcaaagaa agaaaatatg tatgcaatag tagctccagc tataacaggt
     7261 caaatagata gtaatattac atatggtcag ttaaaaaatg ctataaaatc actgggattt
     7321 gtagatatga tagaagcttc ctgtggagca gatgcagtta cagttcatga aagcaatgag
     7381 cttattgaaa gaataaaatc aggagataat tacatgacaa attcatgttg tccgggattt
     7441 tttaagtata tagagaagat gttcccagat gaaaaagata gaatatcatc tacagtgtct
     7501 cctatggtag caacaggaag attagtaaaa aaaatagatt ctgatgctaa agttgtattt
     7561 ataggtccat gtacagctaa aaagagtgag gcaacagaga aaagtttaaa agattcagta
     7621 gattatgtac ttacttttga agaactaatg gcattatttg aagcatttaa tatagattta
     7681 tcaaaatgtt caaatgaaga tataaatgat ggttcgattt ttggaagggg atttggagca
     7741 tctggtggac ttgccaaatc agtacagaac tatattgctg aaaaggggct tagttttgat
     7801 tttgaaccta taaaagtatc tggtccaaga caaattaaaa agacaatgac aatggctaaa
     7861 ttgggaagat tagaaggtaa ttttatagaa ggaatgatgt gtgaagaagg ttgtattaat
     7921 ggagcaggta agtttttatc aggtgtaaaa gctaaaaata cttttgatag aaaaaatgga
     7981 caatctacta aaaagagtgt tttatctaat gataagatta aagaatttga agatgtaaat
     8041 ttagaaagat aattgttttg atacagtcat ttttttatca tgccacaaat atgcctaaaa
     8101 tttgcccttt ttatatgtgt attttacaga gttaaggttg ctatactata aatatgtaat
     8161 aaataaaatt tataggagct tttggatgag gaaaatagta ttaaaagata tcctgttttt
     8221 agttactaca ttatctataa tagtaatatt attgcttgta acaaatataa ctactaatag
     8281 taagataaaa tcaacaagtg aatcttattt aaaaagtgac aaaaatagtg tgaggcaaaa
     8341 tggtatccag aggagcacaa agagtagcac aaaaaatact gcatttaaga ctactatact
     8401 aaacactgga aagtctgatt gcatattggt tgagataggt aacaaagtca taatgattga
     8461 tacaggagaa gataaaaatg gaaaacaaat agtggatagg ttaaaagaaa aaggaataaa
     8521 tacacttgac tatttaattt taactcattt agataaggac catataggtg gagtagatag
     8581 tgtgttatct agtgttaaag taaagaatat tatacaagca aattataaga aagatagtaa
     8641 gcaatatgat gaatatattg actcacttaa aaaagctgat atagaaccag tgctactaaa
     8701 agataatatg aatattgtaa tcaatagtgc agaaataaac atacatccgg cttcaaaaag
     8761 caagtacgag agttcaaatg attattcaac aatcactaat ataagctatg gagcacataa
     8821 gtttttattt gcaggagatg cagaggaaga aagattgtca gagtttataa atggaaatac
     8881 tttaaaatat gattttgtta aaatgcctca tcatggaaga tatgacaaat taactgaaac
     8941 atttttagag tctatttcac cccaatatgc tgttattaca tgttcagaga aaaaagaacc
     9001 agaggaaggt gttttaaaaa tattggaaag attgaatata aaaacatttt tgacttctaa
     9061 tggagaggta gttatcaata gtgatggtaa gacattgagt gtgaatcaat aatttttttt
     9121 aaaatatcta aaaaaattta aaaaaatcat tagcaaatat taccccttaa acatagtata
     9181 ttttaggagc tgaaactcca catacaaaat gactaggagg taacatatta tgttggatag
     9241 attttttggt gaaggcggat ttggtggatg tgcttggtgg ataataatat tattcttctt
     9301 attcttagca ttccaagatt gttgggctga aatggactta tgtgcatgga tacctttctt
     9361 aatattatta ttaatacttt gtgaatgtgg tgacgttttt gatggaggat gtggatgcta
     9421 aaaaaatcaa tttagatgat ttaataaagc ttatggtggg tataaataaa ataccaaacc
     9481 aatcacaatc tagtgtttga aggtagtcgg aaatcccccg ctaccttctt ttttttattg
     9541 ttaaaattta tttttgaatt atttcattta catataataa tttttacgat aaagtctgat
     9601 ataattaaaa agaaaataaa atttatttat aggagatgta aaaatggcta tagtggataa
     9661 gattttcaat gagataaaac ttatggttgc aagactttta ttgggaaaaa aatacagtga
     9721 atatgaagaa aaagatttag tgtataatac agaagaagaa gttatactta taactttaaa
     9781 aagattagtt tttcagggaa atgtaaacga agcagaagaa attttatttg ataaagctaa
     9841 gagtgtaaat agtgaaaata tgcagtatat agcaatagaa ttttatacta tgcttatgga
     9901 aaagactgat gaagaattag aagctatgag tttttctaaa caagaagttt atcaaggtat
     9961 agaagatatt agaaaagtat tgaatttaga ataaaagata tatgaaaata ttgaaataaa
    10021 ttaat
//
LOCUS       DAEQAF010000120         9950 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.124, whole genome shotgun sequence.
ACCESSION   DAEQAF010000120 DAEQAF010000000
VERSION     DAEQAF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9950
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.124"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            727..1656
                     /gene="glsA"
                     /locus_tag="KRN00_003239"
     CDS             727..1656
                     /gene="glsA"
                     /locus_tag="KRN00_003239"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBH1829084.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            1754..2317
                     /locus_tag="KRN00_003240"
     CDS             1754..2317
                     /locus_tag="KRN00_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829085.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            2805..3641
                     /locus_tag="KRN00_003241"
     CDS             2805..3641
                     /locus_tag="KRN00_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBH1829086.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDSLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKKELKMIKEILS
                     SK"
     gene            3925..4920
                     /locus_tag="KRN00_003242"
     CDS             3925..4920
                     /locus_tag="KRN00_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBH1829087.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKDYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(5177..5581)
                     /locus_tag="KRN00_003243"
     CDS             complement(5177..5581)
                     /locus_tag="KRN00_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBH1829088.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            6422..7336
                     /gene="queG"
                     /locus_tag="KRN00_003244"
     CDS             6422..7336
                     /gene="queG"
                     /locus_tag="KRN00_003244"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBH1829089.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRNIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLDYDEIQNISNKEFKR
                     RYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            7442..9679
                     /locus_tag="KRN00_003245"
     CDS             7442..9679
                     /locus_tag="KRN00_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBH1829090.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
BASE COUNT         3994 a          874 c         1851 g         3231 t
ORIGIN      
        1 tgttgggtta gaaatttttg gtgttataaa aatttaaatt actggattat tagattgctg
       61 gattgctaaa ttactaggtt gttaaattat tgaattatta ggttgttgaa ttactaaatt
      121 actaggttgt taagttactg gattatttag atagttagat tactaggttg ttgaattact
      181 aaattactag gttgttaagt tactggatta tttagatagt tagattacta ggttgttaaa
      241 ttattgaatt attagattgt tgaattacta aattactagg ttgttaagtt actggattat
      301 tagatagtta gattactagg ttgttaaatt attgaattgt tagattgttg aattactaaa
      361 ttactaggtt gttaagttac tggattatta gatagttaga ttactaggtt gttaaattat
      421 tgaattgtta gattgttgaa ttactaaatt attaggttgt taagttactg gattattaga
      481 tagttagatt attagattgc taaattatta ggttgttaaa ttactggatt attagattac
      541 taaattgcta ggttgttaaa ttattgaatt actaaattat taagctcttt aaactattta
      601 aattgtttga aaaatgaatt gattcttgta gaaaataatt ttaaagtata atttttttta
      661 acattgtttt attatagtat aaacttgtgc taaaatagaa tatataacat aatataagag
      721 gtgcatatga atacgttaga tgagacatta ttaaaagaaa ttataagttc taataagaag
      781 tatactaatt atggacaagt cgctagttac ataccagaat taaaaaacgc tagaagaaat
      841 gatttaggaa tttgtatcat agatagcgaa aataatcttt atagtgctgg aaactgtagc
      901 acaaagttta ctatacaaag tatttcaaaa ccaattgtgc ttgctatggc acttatggat
      961 aatgattggg aagacgtttt ttcaaacgtt ggaatggagc caagtgggga cccatttaat
     1021 tcaataatga aacttgaaat taatgacaca aaaaaaccct gtaatccaat gataaatgca
     1081 ggggctatag taaccacttc ccttataaat gggagttgtt tagaagaaaa agaagaaaga
     1141 atgcttagtt tctttagaaa gttagcaaaa aatgataata taggaataaa ctatgatgtc
     1201 tataagtctg aaaaaatgac tggagataga aacagagcta tggcttactt attgaaaagt
     1261 gatggattta tcagagggaa tgtagaagat gttctagacc tttattttaa acaatgctca
     1321 attgagatag attctgtaga tttagcgaga attggaataa atcttgcaaa ttatggagta
     1381 gatatagaaa atggtgagca tttaatgagt gaaatggttt ctaggattgt caagacattt
     1441 atgatgactt gtggaatgta tgatgcttct ggggaatttg ctattaaagt tggcattcct
     1501 gcaaaatctg gagttggggg tggtataatg gcttctgtgc cgggacgcat ggggattggt
     1561 gtttatggac ctgcgcttga caaaaaaggt aacagcgtcg caggagttaa agttttagag
     1621 gagttgtcaa ataaactcaa attaaatatt ttttaaaata ttaagaaagg atttttttga
     1681 caacaacata taatttaata tataattaaa ttgtaaagaa atatgaatta aataaatttt
     1741 ttaggagggg tcaatgaaag aggtattggt attacgagat ttggagtgca taaaggctat
     1801 tgcgcatcca cgtagaatag atattctaaa agcatttgac aaatcgccat tgtcagcaaa
     1861 acaattatct caattattgg aagaacctca tgcaaaaata aactaccata taaaaatgtt
     1921 atacaaagtt ggtattttag aattagttga ggaaaaaata aagtcgggga ttgtggaaaa
     1981 gtactattat ccaagtgcaa aaaatgtggt tatagggaat aggatactta atttttcttt
     2041 agacaatggg gaagaaaaag aagaattgta catatcaaaa tttgaaaata tgagtgaagt
     2101 tttttataag gcagcagagg aagatgtttt agaaaatgaa aatatagttg attatcatga
     2161 tatttctctt actcatgatg aattagttga acttagtgac actatgaagt caaagataga
     2221 tgaaatttta aataaaagac aacacaatgt tgaaggttct aagtatgata tagctatggt
     2281 tatagttcct actcttgagg aggaatgtcc tagttagaga attaattatg gattaattaa
     2341 agatataata ttagagattg aacatcaaaa tttacttaat aatcaaaaaa tagtttttgg
     2401 tatgggtaaa acaatgattt tcaatctcta tttttttgtt ttcttatacc tattgtattt
     2461 gtaaataatg tgtatagtgt aagatgtata cactatctga gaagtgctta gataatatac
     2521 aaagtatgta agattataat atttgaaatt gattaaaatg ggtataatta aagtgtaaat
     2581 attaaaatta aaaattaata taaattaaat caatgctaga aatatgttaa aagaggaatg
     2641 agattagttg ggatagaaca tcccttagag cttatgaatt tttagtgaaa aagtactatc
     2701 aaataggaat ctccatcttc atatgttggc taaatgtagt taaggtggag tagttcaaaa
     2761 ttaaaattga gtacaagtag tagtacaaat aaaaggagat taatatgatt aaattaggaa
     2821 cacatctttc aatagcaaaa ggctttgcta atgcggctga gacagctgta tatattggtg
     2881 caaatacatt tcaatttttt agtagaaatc caagaggagg aaatgctaaa gaatttgatg
     2941 aaaaagatat aattaaattt caagaaatta gaaaagaaaa taattttgca ccactgcttg
     3001 cacatgcacc atatactatg aatctgggtg gtacaaagga tgatgtatac gaatttgcaa
     3061 caagggtgat agatgaggat ataagaagga tggactcatt aggaattgaa tacatgtgtt
     3121 ttcatcctgg aagtcatgta ggtggtggtg tagattttgg tatagataga atagtaaaag
     3181 gattgaacaa tgccataaag ggtgatgaaa atataactat acttcttgaa actatgtcgg
     3241 gaaagggaac tgaaataggt tttaaatttg agcaattaaa aagtataata gacaaaattg
     3301 agcataaaga aaaaataggt gtgtgtcttg atacatgtca tattttttca gctggttatg
     3361 atatagtgaa tgatttagat ggggttttgg aagaatttga taaggttata ggcatagaaa
     3421 gattgaaaac tgtccatcta aatgatagta tgatgccatt tggagataaa aaagacagac
     3481 atgctcctat aggggaagga aagataggat taaaagcatt aattgatttt atggaacatc
     3541 ctagtctaaa acatttacca tttttcttag aaactccttt tgatgatgaa ggtcacaaga
     3601 aagagcttaa aatgataaaa gaaatactat ctagtaaata aacctttatt aaaaatatgt
     3661 gaaatacttc accctcaaca taattagggt ggagatacaa tcatgaaatg tgataattta
     3721 aattaatgga taggaataac aaaaattgta tacaaattaa ctgggtataa agtatgatta
     3781 tattatgaat agactgatat aaaatataat tatactatga atagtatgta aatatattgc
     3841 aaagattctc ataatttgtt gtataattaa agatgacata tttatattat ataaaaaatt
     3901 attaaaagtt aggtggggaa agatatgaga aatttaggca atactaacat gaaaataaag
     3961 agagttggct ttgggggcat tccaatacaa aggattactc aagatgatac taacttagtt
     4021 ataaatgagt tagaaaaaca aggaataaac tttattgata gtgcaagagg gtatacaata
     4081 agtgaggaag caatcggaat tgccattgaa ggaaaaagag ataaattttt cttagctact
     4141 aaaagtatgt ccagagatta tgattcaatg aagagagatg ttgaaataag tttaaataat
     4201 tttaaaactg attttataga tttatatcaa ttccataatg ttaaagaaga ggagtatgat
     4261 aatcttttta aagataaaat ggcttatagt gcccttttag aggcaaagga gcaagggaag
     4321 ataaaacata ttggtataac tagtcacaat ttaaatacta tagaaaaagc tatagaagat
     4381 ggaaaatttg acactataca attcccttac aatatagttg aaggacaagc agatgaagtg
     4441 tttaaaaaag ctcatgaaaa aggaattggg ataatagtaa tgaaaccttt agctggaggt
     4501 gctttagaca atgcaacact ggctattaaa tatatactat ctaaagatta catagatgta
     4561 gttataccag gtatggagag tgttgaacag gttagacaaa atgtcgctgt acttgaaaat
     4621 cttgtgctag atgaaaaaga taataaggaa attgaagaaa taagaaattc tttaggtaaa
     4681 aaattctgta gaagatgcga atattgtatg ccttgtgctg taggaataaa tataccattg
     4741 agttttttat gtgaaggtta ttatactaga tatggattaa aagagtgggc taaagaaaaa
     4801 tatgaggtta tggatgttaa acctactgag tgtattgact gtgggctttg cgagagtaga
     4861 tgtccatatg aacttcctat aagagaaatg cttaagactg ttgttgaaaa gctaggatag
     4921 attttattta ttgaaatcgg tgtattaaat ttactccgat ttctttttat tagatgtggt
     4981 cttatataca aatattaaat ttacatagtt atagctatta tataaattta atatttgttt
     5041 aatacttatt aaatatttgc ttaatgcttt ttaaaaacat ttgtttgagt atagacataa
     5101 cacaattatt attgttgtat tagtatagtt tcaaatactg gagtatcaat ataatgtcga
     5161 ataacacata aaatctttat ttttcaaaaa tattatagga tatatcgtat ttagatactg
     5221 gataaagttc aatttcaacc ctagggttat ctttatctat aaaatcaaat agaagtactg
     5281 gcttaagttg tttatcattt tttattattc cacttttttc aataccatca caaatacttt
     5341 ttggataatt atgtaaatcc cccattctct tatttgggaa gaataatttc aagactgtta
     5401 ttagattttc ttcaacagtt tccccttgat actgttggtt tataaaacct gcaatcatgt
     5461 tttcgtatgc aagatactta gaatattttc cctttgaagg catccatgct tgaccattta
     5521 tgttatgaag cttaaaatta gatttactaa taggtctacc tggaattgtt attttaatca
     5581 aatttttcac catccttata cagtatttat tataatctgt atatgattta aaagcaaatt
     5641 gttatttaaa gtgtttttac agagcttgtt tgtaaaattt tccactttag atgtagtaat
     5701 ataagataaa tattttgctt acaaatttta aaatttgata tatgatggac atattcatat
     5761 tagactatta taagaccttc ataatattaa taagtataag tttagtaaag agagtaaaaa
     5821 gaaatccata taagtcaagt aaagacttaa taaatggcaa tgtaaatggg atattaatta
     5881 taagaaaaaa tcaatctttt tgcttaacta tagaaagaat gtcaaaatat aactaatgat
     5941 atttgaagtt ttagagttta tattaaaagg taagaaggtt aagtgggtaa aaaaggttga
     6001 atagattaaa aaggctaagt atctaaaaga gttaagtagg taaaaaagtt aaataagtaa
     6061 atgaaaaagg ctaagtatct aaaagagtta gtaggtaaaa aagttaaata agtaaataaa
     6121 aaagatgaag tatctaaaag agttagtagg taaaaaacta aataggtaaa aagatgaagt
     6181 atctaaaaga gttagtaggt aaaaaattaa ataggtaaaa agacgaagta cctaaaagag
     6241 ttagtaggta aaaaaattaa atagataaaa agacgaagta tctaaaagag ttaagcaggt
     6301 aagaaaattg aatagctaaa aagattaagt atttaaaaga gttagtagct agaaaaggtt
     6361 aaaaagacta aaaaaattaa ataaatttaa aaagtcaatt agattaaaaa ggaataattt
     6421 tatggataat aaggaattaa aagcattttg taatttaata ggattaaact gtgtaggagt
     6481 agcaggggta gataagtatg ataatttaga aaagatactt aaggacagac aacaaaaagg
     6541 ttatttaact ggtatggaag aaccaataat tgagaacaga attaacccaa gaaatataat
     6601 gaaggatgct aactctataa tagtctgtgc atttccatat catataaata gacaagaaaa
     6661 gaataaaaat tcaaatttat caaaatattg tcatggaaag gattatcaca ttgtagtaaa
     6721 ggacttttta caacaaattt gtgattatat ttctaaaaca gtaacagatt ttaaatacaa
     6781 gttatttgct gataatggac cattagttga caggtattta gcttatttat caggaatagg
     6841 atattttgga ataaataata atatcataac tgatgaatat ggttcttacg tatttatagg
     6901 gtatatagta aataattata aatttgaaga agataaacca ctagaaaaaa gttgttttaa
     6961 atgtggtaag tgtgtaaaat attgtccggg aaatgctata ttgggaaatt atgatatgaa
     7021 ccccaaaaaa tgtttatcat atataactca aaaaaaagga gatttgtcag agaaagaaaa
     7081 agttgtttta aagaatggca aaaaggtatt tggatgcgat atttgtcaag aagtatgtcc
     7141 acataatgtt gaaataccaa caactcatat tttggaattt aaagaaaata taatagatta
     7201 tttggattat gatgagatac aaaatatttc aaataaagaa tttaaaagga gatatggaga
     7261 tagagctttt agctggagag ggagaaatat aataaagaga aatatggaaa taattttaga
     7321 taagtatgat gactaataat aagagtctgt ttcatatact ttaatgtgta tttactttaa
     7381 cacttgttgt gtaaaagtca tattatatca ttaaagttaa atatggggag gtgggggaat
     7441 attgaaatat aataatacat ctgaaataaa tccactagat tatatattgg gtcaagaaag
     7501 agctgtagaa gctatggaat tagggttgaa aataaataat ccagcgtaca acatatatat
     7561 agctggtgaa cctggaactg gtaaaagtac ttatgcctta aaggttttaa atgagtatgc
     7621 atccaaaaaa aatacgcata aagattggtg ttatatatat aattttgaaa accctagaga
     7681 gcctattata gttgaattag aaaaggggtt tggaagagaa cttaagaaag atatggagaa
     7741 attaattgaa agtcttttag aagattttaa aaatgcgttt gaaagtgaaa attttgaaat
     7801 agaaaaaaat aaacttctgg atgaatatga aatagaaaaa gatatgcttt tgaagcaaat
     7861 taaaaaatat ggagaagaaa aaggatttaa attaaaacag agtaaaatgg gaatagtttt
     7921 tatccctttg aaagaagagg aagatgaaag tgatgagtct gatgaagagt tttacaaagc
     7981 taaaagagaa ctagaaaata tggcgataca ggtcgtatat aaaattagaa acttagaaga
     8041 aatagctgaa aaagcagtgt tagagcttga agaagagata gctaaacttg tagtagaacc
     8101 tcatatcaag agattgtgtg aaaaatatga aaattatgat aaaattcaaa cttatctgga
     8161 aaatataaag aaagatataa tagaatatat gtatttattc tatttagatg aagaggagtt
     8221 aaaagataag tatgataaag agcattttat taaatataaa attaacctat ttgtagacaa
     8281 tggaagctca aagaataaag aatcagcacc tgttgtagta gagataaacc caagtccagc
     8341 aaatctattt ggaaaggcag agtatgatta tgcaaatgga aatataaaga ctgatttcac
     8401 aaaactatta tcaggagcat ttcatagggc taatggtggt tatttagtac tttatgcaga
     8461 ccaattacta aaatatacaa tgtcttggga aattcttaaa aagactttgc agactaaaaa
     8521 agtaatattg gaaacacaaa cagcaattaa accagaaaat atgccattgg atgttaaatt
     8581 agtactgatt ggaagccact atatatatga tattttatat agatatgatg aagattttga
     8641 aaaatatttt aaagtatttg tagactttga tagtgaaatg gataaaaatg aagataatga
     8701 agaaggaata gcaagattta tagcatacca atgtgataag aataatttaa ggcattttac
     8761 taaatcagca gttgaagagg ttattaaatt tagcactaga ttgtctggtg atttagaaaa
     8821 actatcaact aagtttaata aaataatgga agttgtaata gaaggaagtg cttatgcaga
     8881 gtttagaaat tcggagtata cagagcagtg tgatgttaaa aaagcaataa gtgaaaagag
     8941 aaaaagaatt aatagagtgg aaacacatat ggatgaatca attgaaaatg gatttactct
     9001 aatagaaaca gagggacgaa aagtaggagt gataaatggt ctgtcagtct taagtacagg
     9061 agaatactct tttggtagag cttcaaggat tacagcgacc actagcccag gaagtaaagg
     9121 catagtaaat atagaaagag aagtaaatat gagtggttct atacataaca aaggagtact
     9181 tatattaggt ggttatcttt ctgagaattt tgcacaggat ttactattgt cactaaatgc
     9241 atatgtttgt tttgaacaaa attatggtgg aatagatgga gatagtgcat cttctgcaga
     9301 attatatgta ctattatcat ctcttagtgg agtatcaatt aaacaaaata ttgctgttac
     9361 aggttctata aatcaaaagg gtgatataca agtagttggt ggtataagtg aaaagataga
     9421 aggattttat tctatatgta aaactaaagg gttaaatggt gagcaaggtg tcataattcc
     9481 tagaaaaaat caaagaaatc tcgttttatc agatgaagtt aatgatgcag tgcgagatgg
     9541 aaaatttaag atatatactg ttgaaagagt agaagaggct atagagatat tgacagatgt
     9601 taaatttgaa gaaataaaga aattggtaaa agaaaaatta atatctttca gcaagataca
     9661 aactgtgtca aaagaataag tttattatag aatttaatgg gtatttatgt ataataaaaa
     9721 gcaagaactt taataggttt ttgctttttt tgtaaatata tataaattaa attcttattt
     9781 tgtatgtttt atatattgat gtttattttt ttgttgatat gattaaacta tttataaata
     9841 gagttttata aattggtatt ttgaaggggg ataattatga aaaatgtaaa tctaaaagag
     9901 ataaatgaaa aagatgtaat tttggaagaa gagataaata aaaaaggaat
//
LOCUS       DAEQAF010000121         9736 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.125, whole genome shotgun sequence.
ACCESSION   DAEQAF010000121 DAEQAF010000000
VERSION     DAEQAF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9736
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.125"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            173..1183
                     /locus_tag="KRN00_003246"
     CDS             173..1183
                     /locus_tag="KRN00_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBH1829091.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAVEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            1319..1807
                     /locus_tag="KRN00_003247"
     CDS             1319..1807
                     /locus_tag="KRN00_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBH1829092.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            1983..3911
                     /locus_tag="KRN00_003248"
     CDS             1983..3911
                     /locus_tag="KRN00_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1829093.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFEDLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            4088..4498
                     /locus_tag="KRN00_003249"
     CDS             4088..4498
                     /locus_tag="KRN00_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBH1829094.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            4520..4822
                     /locus_tag="KRN00_003250"
     CDS             4520..4822
                     /locus_tag="KRN00_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBH1829095.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(5039..5731)
                     /locus_tag="KRN00_003251"
     CDS             complement(5039..5731)
                     /locus_tag="KRN00_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBH1829096.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMIAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(5757..6944)
                     /locus_tag="KRN00_003252"
     CDS             complement(5757..6944)
                     /locus_tag="KRN00_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1829097.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQKATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            7280..9079
                     /locus_tag="KRN00_003253"
     CDS             7280..9079
                     /locus_tag="KRN00_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1829098.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNIGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGAA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFD"
BASE COUNT         3706 a         1066 c         1724 g         3240 t
ORIGIN      
        1 ccacatattt tgggtattgt atactggaat tagagtaatt aatttatttt ttaacataca
       61 aatgatttta tgaaaaaaaa caagactcaa aaatttttat attctttgat agaataaaat
      121 tgagagtaaa tttattgaat tttataaaat ttataagggg tgagtttaag atatgcatga
      181 agataaaaat gatatatttg aatcaataga tactgaggat tttgataata aaacagaaga
      241 agaatgttta gagctagtaa gaaaaaatgg attgaattta atatacataa aaaatcaaac
      301 agaagagata tgtctagagg ctgttagaca aaattgtaat gcaataaaat gtgttcagaa
      361 tcagacagaa aaaatatgta tagaagcagt taaacaagat tggagaatgt tagagtttgt
      421 ggaagagcca acagaagaaa tttgcatgtt ggctattaac caagatggaa cagcattaaa
      481 atatatagaa aatcagacag aggagttatg cttaagagcc gttgaaaaaa atggtgcggc
      541 tttggagtat gtaaaagaac aaacagaaga aatatgtata gaagcagtta gaaacagcga
      601 atttggattg gcaagagtga aaaatcaaac agaaaaaata tgtatggaag cagttaagca
      661 ttgtagctat aatctaaaat gggtagaaaa tcaaacagaa gaaatatgta tggaagcagt
      721 gagacaaaat gggcttgatt tgaaatttgt aaaaaatcaa acagaaacaa tctgtttaag
      781 agcagtgaga caaaatggaa tggcattaga atttgtaaag gaacagactg ttggtatatg
      841 cttaaaggca gtaagacaat atggaatggc attaaaattt gtaaaagaac aaacagaaga
      901 aatttgtaca gaagctataa aacaagataa aagagcactt agttttgtaa aaggagataa
      961 ggaaaaatac aaggctctat atgataataa tgaaccattt gcaaagagat atgttagaaa
     1021 tgtaatagaa aaagaaaaca gagcattgat taaaaaagga gaagaaaatg caaaaatcaa
     1081 aattgcagga aaactttatg atagaggcat gtcttttgaa gatatatcag atatagttga
     1141 gattgaaata agcaagttaa aagtgagttt aggtgttttt taaagtaata aatgtaggtg
     1201 ttttttatgg gaaatagtta ataaaaaaat aatcgactag ctctttgtag gacagcaaaa
     1261 ttagtgatat aatttgatgt ataataaatt atttttatta gataaggggg aattaaagtt
     1321 gaagattaca gtattatacc aaacaagaag tggaaacaca gaaagggtcg ctaagctgat
     1381 agaagatgga gctaaaaagg tggatggagt agatgtaaag cttatgagac ttgataatat
     1441 tgatttagat tatttaaatg aaagtaaagc agtaatattt ggaacaccta cttatttagc
     1501 aaatacaact tgggaagtaa aaaaatggtt tgatgaagat tcaaaaaaag ttaatttagc
     1561 tggaaaatta ggagctgttt ttgctacatg tgattatata tgtggaggtc cagatgttgc
     1621 gatacttact atagtaggac atttgatggt taaagggatg cttgtgtatt ctggaggtgg
     1681 ttctttagga aagccattta tacatttagg acatgtacat tcaattgaag gtccagagtt
     1741 acaagatgag aaggctataa tatttggtga aagaattgct actaaggcaa aagaactatt
     1801 tgcttaattt ctatatgcat agtaatgatt agagtaaatt tagggtttta atggagattt
     1861 gaagtaaaag ttataaaata aaaaattttc cataaaatta ctcaagatga attataatat
     1921 aattataaat aaattatatt attaaaatat ttaaaatcaa acgtcaatag cgagggaagt
     1981 ttatggtatg gcatatagaa tatgagattt tttctgcaat tatagttatt tttttaatgg
     2041 tatacttttt tagaagtaaa tttataccta ctttacaaaa caaaatatat tgtgcacttt
     2101 taatattctc atttttattt ataatttcaa atattttagg ttcattttgt ctaaataata
     2161 tagacaaaat tccaattttt attacttttt tattgaatca gatatactta ttgttattgc
     2221 caataccagc agcacttgta tcattttatg ttatggctat tatttatcaa gatataaggt
     2281 atatgaaaaa aagattatta tttttatcta taccacttat aatttgtata atcttatcta
     2341 ttacaaatcc ttttacgcat attctatttg gattgtcaaa agaaacaggt tatatacgag
     2401 gttgtggata tgttgcaact tttgcatctt ttttctttta tgcaatatat tcagcatttt
     2461 tatcttttaa atatagaaaa gcaatgcatg aatcaaaaat atgggctatt agaggttttc
     2521 ttatagtttc aattgtggca attatcttac aggcaatttt tttacagtat cttcttacag
     2581 gaactgcatg tgcatgtagt ttacttttga catatctttc tatgcagaat cgaggtctta
     2641 ttattgatga ccttactggt gtactcaata gacaatcttt tattcaagag ctagatttga
     2701 atatcaatac tgaacaatca ggatttatta ttacaattgc gcttgatgat tttaagttta
     2761 tgaatgaaac ttttggaaca aaaaatggag atattgcact aaaagaagtt ggaaaatatt
     2821 tgattcagat acatgatgta aaccatgtat atagaatagg gggagatata ttttctattg
     2881 ttgtcaatag tcaattaggt atagaaccag atgatattat cagaaagata gaagaaagat
     2941 ttaaaaagcc ttggctagta gaagagataa gttttaattt agcaactagt attgctgttg
     3001 tttattaccc agaaaatgca gaaacgacag aagatgtaat tgttgctata gatttctcta
     3061 tacatgaagc aaaacgttct gagtcaaggc gagttgttta tgcagatgcg tctataagtg
     3121 aaaagataaa gaagaaacat gttattaaaa attgtttaaa agaggcatta aaaaatgatg
     3181 ggtttgaagt gtactaccaa cctatatttt ctaatagcag gggcaggttt acttcagcag
     3241 aggcattact taggctagaa cacaaagagt taggttttat acctcctgat gaatttattc
     3301 caattgcaga acaaacagga ttgattaact caattggatt agtagtcttt gagaaggtat
     3361 gtagatttat agctagtgat gagtttgaag atttaaaatt ggataatata gctgtgaatc
     3421 tttctgtagt acaatgtatg caaaaaaact tagctgatga tttactttat cttatgaata
     3481 aatataatgt atcaccaact aaatttaaac ttgaaattac tgagactgtg gctatgggct
     3541 cttttaatat aattaaagaa acaatggaaa gattaattga tttaggtgtt aagtttgcac
     3601 ttgatgattt tggaattgct tattctggag ttactaatat gctttcttta ccattttcag
     3661 taattaagtt agataagagt ttgatttggt ctatgaatga agatagtagg cataaactta
     3721 cagttgagac gattatagca cttataaata aattgaatat gaaggctgta gcagaaggtg
     3781 ttgaaaccat taagtgtgct gaagatttaa tagctatgga gtgtgaatat ttgcaagggt
     3841 attatttttc taaaccagtt ccagaagatg tttttaaaaa tttgttgaaa gaaaatactt
     3901 ttacaagtta acacccttta tttttttaat tacaactttg ttcattgaca ctgccagcga
     3961 tatattataa aattaacaca ataataaata ttaaatttat tatacatatt attaatatta
     4021 attaatggag taaagattta ttatatattt tatttaatta tcctaaagtg agaaaggaag
     4081 atgtgacatg aataaaaaga aaatattagt gccaattgat gggacagaaa gaagtatgca
     4141 ttctttggaa tttataaaag gaatatttaa aaaagatgaa gttgaagtag aaataatgaa
     4201 tgtaaaagaa ctagtattta ttgatggcat atccctggct gaagagataa aaaattctga
     4261 aaatttagga agaagaatct tggataaagc agcagagata atgggagagt atgatgttaa
     4321 agtacatttt acttttggat atccaggaga tgagataatt agaaaagcaa aagaagataa
     4381 tgtagatttt atagttatga caaaatctac taaaaaaggt cttacaagaa tgataggttc
     4441 agtaacagca agtgtagtta aacaagcaaa atgtatagtg atgattgtac cggagtagaa
     4501 ttagaaaggt atttgaaata tgaataaaaa gatagtagca gtttgtgaaa gtgaaagaag
     4561 tttaaattct cttaagacag ctgcaaatga tttaggattt gatttagttt atgaaattca
     4621 agaaaatgat aatataaaaa atgaactttc tatttatgat atagaagatg catccatagt
     4681 gttatttgtt acaagtgatt ctatagaaag catagagaag attgatagat ttatagatag
     4741 agaattttat gaagttgatc caaagtatat aatagaggat gcaaaatcta tagtaagtga
     4801 aattttaata gacttaaatt aatcgtgggt gtcgcactaa gaatagagcg acgccttttt
     4861 atatatttta cacaagaaat aaagaggttg tatcaaaata tagataagac tctttttcat
     4921 tgttgaaatg atgaaaatat atttgatttc atacaaaaaa gagtacctca taactaaaaa
     4981 gttcactttg agacactcca tttttatatg ttagttgcat ttaaggtaaa atagaagttt
     5041 aatcatgttg aaataactga attacatctt ctaaatgatt gtacattgat gtataaccta
     5101 agtaagagtc tttactatca aatgcaatca ttatcttgtt atggtggcta atcatatcct
     5161 tgagagaatt tctatattta aaaccaaagt attggttaga agaaactgtt ttaggtatta
     5221 actcataata ttttataaaa attggattat gagaagctaa aattatctct ttgtgaaatt
     5281 gcaagtcagc atcataacat tcttctatca aaccatgaga aaccttatcc aattcctcta
     5341 ttgactttag gtaagtatat tttatttttt gaagttcttt agatgtagca tttaaaattg
     5401 ctagtttagt agcttcgctt tcgataagtt gtcttgctct taaagattct acataaaatt
     5461 cttgtatgtt atgattttta tagatttcac catcatcaaa taggtcaact tttttaaatc
     5521 cttcaactat aggacttgaa taaggcacag ctctaagtat tccttcctta cagagtatat
     5581 ttatggcatt tcttacaggt attctactta tgttaaatag gtcagcaatc tttctctcac
     5641 ttggtaattt actattaatt ttaaaagttc catttagaat gtttaattta atataatcaa
     5701 taattttttc agtggcattt aagcttttca taaaaactcc taaacatata atttttttat
     5761 gattgtatta tatcatagtt aagagttaaa tctacttttt tataatatgt ataagacagg
     5821 atagaggcca aaatagctat aatagccaag ataaagtatc catattgtat tgaagtatat
     5881 tccgatattt taccaactat cattggaaat acagacattc ctatagcata aattgcttga
     5941 aaaaaaccca ttgcagtaga tttctgatgt tttggtacat ttttcataga ctcgctagta
     6001 aggtaagaaa ggagtatacc tgtagatata cctggtagta cttgtagtac aaatattata
     6061 ttaatatttt ttattgttgg aactaaaaag caataggctg aaactaaaat aaaaactaaa
     6121 ggaatccaaa attttggccc atacttagta caaaatttag tagaagcaaa gccagaagaa
     6181 gcaacagcac acaccatgta aaatatagaa gatagaccta tgagggtaga actagaacct
     6241 aagtttttaa gaatttgagt agtaaatgac attgttgtag acatttgaat accctgttga
     6301 attaatgcca taaaggaaaa aaatacaagt cttttatcct tgcagataga taaatatttt
     6361 ttaattgata ttttttcagg tatttttttt gaattatgat tttttatatt taaggctaga
     6421 atcgttccaa taactgaaga caatacactc atgatacata aggctgtcat tcctaatttt
     6481 tcataaaata aagtactcat aacaaatcca atcaacattc ctagattgtt taccaatatt
     6541 atcgtacttg tagctttttg ttgatgttct gtagaaaaaa agttggtata gtgaaccatg
     6601 taagaaatcc aagttgatga tgatattcca gataaaatgt tagctataag aaaaccattg
     6661 cctccaggag aaaagactct tataagagat gctaaaccag caaagaaaat tccagacagt
     6721 ataaatattt tatgtttatt tatggaatca gcaaatactc caacaggaag ccttaataaa
     6781 cattgtgaga ttccatatgc acctattatt ataccaatca tatttgtaga tacattacat
     6841 gcacttaaat atggattttg gaaaggtata tatacatatt gtgaaaacca gaaaaatgta
     6901 acaatagaaa gtaaaagtaa tttttgatta gatatttttt tcatattatc ctccgtatgg
     6961 tatttttata atgcaaataa tataccattt ggatttttta atcaagtact ttctctatta
     7021 aaaaaaattt aaatatataa ttattattta caaaaaaatt atactttata gttgaattaa
     7081 gaaaacgctt atgatactat aaagttaaca aatttgaata tataacagta gacgtgttac
     7141 tggtaatgca ggcaagatcg aatcaatttt tatagattat ctatagagta ctatgggtat
     7201 aatctattta tttggttcga tttttttgtt taattggcca taaaacaaaa agcctatagt
     7261 tgaaaatgga ggatttttta tggattataa aaatatagct caagaaattc tactaaatgt
     7321 aggaggaaaa gagaatgtaa atgaagtgac tcattgtatg acaagactta gatttaaagt
     7381 caaaagcgct tctaaagtga ataaggataa attatctaaa actgaaggag taataactgt
     7441 tgttgagagt atgggtcaaa tacaagttgt aattggaaat aaagtaaaaa aagtatatga
     7501 tgaggttata aaaattgtac ctcaatcaaa taacataggt aaaaagaatg aaagtcaaga
     7561 aaagcaaggt ataattaatt ctatattatc agcagtagct ggtatattta cacctacaat
     7621 acctgctata gcaggggttg gtatgattaa aggtatttta tcagttcttg ctatgtatta
     7681 tatgaataaa aatggagtag atataaaaga aacgcaaagc tatattatct taaatgctat
     7741 ggctgattct atattctatt ttatgcctat tatactagga tatactgcgg ctaaagtatt
     7801 taatgcaaat aaaataatat ctatggtatt aggagctaca ctttgttatc caacttttac
     7861 tgctttgatg gcaggtgaag aatctgttag atttttagga ttggcagtaa caaaagctac
     7921 gtatacatca tctgttattc caataattat tgctatatgg gctctttcat acgttgaaaa
     7981 agtattagaa aagtatatac ctgaggtaat taaaataata atggttccaa ctttatcatt
     8041 ggttgtaatg ttacctgcaa cattattttt atttggacca atcggaattt atataggaaa
     8101 tgtcataaac ttttcttata agtatattta tgaattaagc ccagcattgt gtggagcatt
     8161 tgtaggtggg ttatggtgtg tgttggttat atttggtgct catagagcat tattaccaat
     8221 aggtataagt gatgttgctc aaacaggaag acagaattta ttggcgtttg caggagctgc
     8281 aaacttttca caagcagggg ctgctctagg agtattcttt aaaactaaaa atcaaggact
     8341 aaaaacaatt tctatgtctg caactataac agctttattt ggtataactg aacctgcaat
     8401 atacggtgcc aatcttagat taaaaaaacc tatggtatgt gccgtaatat gtggtgcatt
     8461 tggaggtgcg ataatgggaa tgggtggagc ttatggtaat gcatttgcaa accaaggtgt
     8521 tttaactata cctgtatatg ctgaagcagg tgcattaggt ttcttaagtt atctaggtgg
     8581 ttgtgctata gcattttttg gttcagctat ttcaacttat ctagttggat ttgaagattt
     8641 ggaagagtct tctaataagg aaaattcatc tataaaagta gaaacgaagg atggtgttat
     8701 tgatataact tcacctgtag agggcgaatg tatagaattg tcagaagtaa aggatgatgt
     8761 atttgcttca aaagctatgg gagaaggtat agctgtgtta cctacaaaag gagtaataac
     8821 agcccctact gattgtgaag tagcttcttt atttccaaca ttacatgcaa taggattaaa
     8881 attagataat ggagcagaaa tgttaataca tgttggaatc aatacagtag agttaaatgg
     8941 taaatacttt acaaaacatg ttaatcaagg agatttagtg aaaaaaggtg ataaacttat
     9001 atcctttgat atagataaaa taaaaaaggc tggttatgat gtaactacgc cagttatagt
     9061 aaacaataca tttgattaaa aaatagctac gcacactcgt gactttagtc atgagttagt
     9121 agctaaaata gtcagcatat agggaaacct atatgtagag ataggataga acctatccaa
     9181 tactacttga attgctggaa acccctaaag ctaaccaaac taaaacataa ggatgaaata
     9241 aacctaagtg tgaaagttac gaaagtagaa aaaattggtt agatggtata aggttaaatc
     9301 ctaagtactt taaaatgggc aatcagcagg taaactccga ataggagaaa cttcaacgac
     9361 tattcctctt gagggaagta cactacaagc tattggtagt ggaagtgggt agaccttaac
     9421 ggataatgcc gaaggataag atatagtctg tgcttgcatg aaagtgtaag aagttcataa
     9481 gagaactgca taggtagtag cgaacttatg tgaacgacaa cctcaaaaat gataaaagtt
     9541 aagacttacg gttcttatat atgttattta aaattaaata taaaaccttc taaataattg
     9601 ttttaaataa ttacatttgt taatattatg ataggtgatt aataaattgt tcaccacagc
     9661 attatataat atattaaata tgataaaatt attaaaaagt gtatcaaaaa acaattaaag
     9721 tgaggtgata gcagtg
//
LOCUS       DAEQAF010000122         9192 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.126, whole genome shotgun sequence.
ACCESSION   DAEQAF010000122 DAEQAF010000000
VERSION     DAEQAF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9192
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.126"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            393..1598
                     /locus_tag="KRN00_003254"
     CDS             393..1598
                     /locus_tag="KRN00_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBH1829099.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVDPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTDRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1669..1890)
                     /locus_tag="KRN00_003255"
     CDS             complement(1669..1890)
                     /locus_tag="KRN00_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829100.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2031..2630)
                     /gene="recR"
                     /locus_tag="KRN00_003256"
     CDS             complement(2031..2630)
                     /gene="recR"
                     /locus_tag="KRN00_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBH1829101.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2643..2993)
                     /locus_tag="KRN00_003257"
     CDS             complement(2643..2993)
                     /locus_tag="KRN00_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBH1829102.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="KRN00_003258"
     CDS             complement(3052..4689)
                     /gene="dnaX"
                     /locus_tag="KRN00_003258"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBH1829103.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4766..5030)
                     /gene="ffs"
                     /locus_tag="KRN00_003259"
     ncRNA           complement(4766..5030)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KRN00_003259"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5068..5159)
                     /locus_tag="KRN00_003260"
     tRNA            complement(5068..5159)
                     /locus_tag="KRN00_003260"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5123..5125),aa:Ser,seq:gga)
     gene            complement(5160..5615)
                     /locus_tag="KRN00_003261"
     CDS             complement(5160..5615)
                     /locus_tag="KRN00_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBH1829104.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNRIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5936..7207)
                     /gene="serS"
                     /locus_tag="KRN00_003262"
     CDS             complement(5936..7207)
                     /gene="serS"
                     /locus_tag="KRN00_003262"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBH1829105.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7333..7538)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7666..8547)
                     /locus_tag="KRN00_003263"
     CDS             complement(7666..8547)
                     /locus_tag="KRN00_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBH1829106.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8559..9068)
                     /locus_tag="KRN00_003264"
     CDS             complement(8559..9068)
                     /locus_tag="KRN00_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBH1829107.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNIYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
BASE COUNT         2944 a         1606 c          972 g         3670 t
ORIGIN      
        1 ttcctttttt caaggacaag taatactata tcatctttat ctattctagt caatataatt
       61 ttttactttt tttaattttt ttatttatca tgtattcttt atctttaatt tttaaaactt
      121 aatgctaagt aaacctgttt atttcataaa actaatatat attctatgct ctattttcct
      181 ttttattcta tatttaaatt ttttatttac aagaatattt ttaatataac atatttgata
      241 aaattaattt acatttcttt cacttgtaat ttttgcaatc ttgtattaga ttaatattaa
      301 aaataattta tcaataacct tattcacaaa gacagttttt atatatcaaa atataatata
      361 aatactatgc tacattttag gaggatttta ttatgagcaa aaaagtatta ataatgtctg
      421 cttccactgg tggtgggcat aatagggctg ctctagctat taaagaagaa cttacttcca
      481 aaacacttga tggagagcca attgaatgtg aaataataga tagtttgaaa ttagttaata
      541 atacaatgga taaaataatt tcaagaggat acgaaaaatc tgctatatat actcccaaag
      601 cctatggaag tgtatataga ttatctgaaa caaatctttt gtcaaaaaat gaatttaaag
      661 ataatctact aataacattc atggctaaaa aatttaaaaa gcttattaga agcgaaaaac
      721 cagacttgat tataggaacg catccttttc caatgattgc tctaagtaca ttgaaaaaaa
      781 actttaattt acataataat gaatcaaatg cttacacaga gcatttttat aaacattata
      841 caaataccat taatgttcct ccgcttattt ctgtattaac cgattatact actcattcta
      901 catggataca aaatgaaatt gattactata ttgttggtca tgaatatgta aaagaattat
      961 tggtgtttga tggagttgac ccgagtaaaa ttagaacatt tggaatccct gttgaaaaat
     1021 cttttctctc tcacagagat aaagatattg ttctttctga gttgaattta tctcctgata
     1081 aattaactgt tttacttatg gggggtagct ttggggctgg aaatataaaa gagacacttg
     1141 atgaattact ggatactgat agagactttc aaatacttgt aattactggt aagaatgaaa
     1201 gcctaaaaga aaaaatcgaa aaaaaactta tgtctcgtta tcatgataaa aatgtatgtg
     1261 ttcttggata cactgataag atgaatgata ttttagcttc tatagatgta ttagtaagca
     1321 aacctggtgg acttactaca actgaggctc ttttaaaaga tgtacctatg atagttcctt
     1381 attatatacc aggtcaggaa gaagagaatc ttgatttctt atctaattgt ggtgcagcac
     1441 ttagaactac aaaaaaatat aacttgtcaa tattactaaa agttttaata gatgacccta
     1501 gcagattaga aatgctaaaa agaaatatta aatcaataag aaagtcaaat tcagcccaaa
     1561 atatagctaa tttaatttta aatataattt ctggttgata aaataaataa aatccctata
     1621 gtatatatat tatctattag ggatttttta ttttctaatt atttaatatt aaattggttc
     1681 ataaaagtct tcttcataat catactgata atttttataa ttatttctaa attcagcatt
     1741 tttatttcgt acattttttt tagttttttt cttattagaa aaacttatat cctcaaaatc
     1801 atcatattta ggtttatctt ttgatttcat ttttttaact cttttttctt tcattgcatt
     1861 atgttcttct aagttcataa ttggtttcat gttgcacccc tatcaaaatt tttaaatgat
     1921 ttatacaaca aattatacaa tacagaagaa atttattcaa taaatctaaa tcaaaattaa
     1981 tttgaattta actcaaaaaa ctacaaaaat cgaggtatta acctcgattt ttatatttct
     2041 cttctgcctt ctagtgcttt tgatattgtg acctcatctg catactctaa atcgcctcca
     2101 acaggaagac catgagctat ccgagtgact ttgattccca ttggttttac taacctagca
     2161 atatacatgg ctgtagcttc accttcaata gtaggatttg ttgccattat tatttctttg
     2221 acttcctgat tgccaagtct ttggataagt tcctttattt ttaacatatc tggtccaatt
     2281 ccatccattg gagaaattac tccatttaat acatgatact gtcctttaaa ctctctcgtt
     2341 ctctccatag ctgctacatc tcttggatct tccacaacac atataacact tgaatctcta
     2401 cttttatttg aacacatgct acatgggtct gtatctgtta tattacaaca aattgagcaa
     2461 tatcttattt ctctttttgc atctataatc gctttagata aagcttccac atcattagta
     2521 ttcatattaa taatatgaaa agccaatctt tgagcagtct ttcttcctac tccaggaagc
     2581 tttgaaaatt cctctataag tctcgttatg ggacctgtat aaacttgcat aaataccacc
     2641 tactagaata acccaggtat attcatacct ccagttacct tactcatttg acttgcttgt
     2701 atatcatcaa tatttctcaa tgcttgattt actgcactta aaactaaatc ttgtagcatt
     2761 tctatatcat ctggatcaac tacttctggc ttgatagtta tatctataac ttctttttta
     2821 ccattaactt ttacagtaac tgctcctcca ccaactgaag cttctacttc tttactttct
     2881 aactcttgtt gagctttttg catattttct tgcatttttt gagcctgctt taacaagttg
     2941 ttcatatttc caccaccagg catcattccg cctccaaaac cttttttagc cataaacact
     3001 attcctccta aacttatttt cattttatta ttatatcata atagtatttt attatttact
     3061 ctcattttca tcaatactat cttttatttc taatatctct tcactcacta tgttctttaa
     3121 tatctcctca ccaatgtcct ttttctcttt aacttcaaga tttatatctt taacttctga
     3181 tgtcagtact atttttacat taaaacttct atttaaaaca tctcttattg ttttttctaa
     3241 ataatttatt gtatcttgag agctcagtct agtttttgca aaatcaaatt tatcatcaaa
     3301 tataacatac aacatattag aatatacatt aaaacttttt acttcactta agagtgcgta
     3361 tattggcatt tttttatctt ttttaatttg tttaagtata ttcttccaag atgactctat
     3421 aagtataaca tcctcatttt ttacatcttc ataaactaca ttttcttgtt ttacatctat
     3481 ttctctatcg acctcatact ctttttcttt attattccca attttttcag acttaaagtt
     3541 ccccagttca atcatttttt ctaagttctc aactcttttt ataagagctt ctttactttc
     3601 atcaaacatt ggttgagcaa ttttcattat ggttatttcc actaaaaccc ttggatttga
     3661 agatgacttt atatcatcct gagttattga taatatattt aaaatcctta ttaaatcatt
     3721 tatatctata tttttagact gaattttaag ttgttctata gtttcttctg gtaatgaaat
     3781 tatttcatcc aattctgatg aaaccttaca taccattaaa tttctaaaat gatcaattaa
     3841 gtcatttata agatttctta tatctttgcc ccataagaca aattcattta atatctcaag
     3901 agacttttta gtgtcctgct ctacaataca ttgagacaat tcaaataatt gttctatatt
     3961 tacgcttccc attaattcaa caacatcttt ataatctatc ttactttctc caaaagacat
     4021 acattggtct aatatactaa gtgcatctct aagagctcct tgagaatttc tagctattaa
     4081 attaagagct ttatcatcta tatcaattcc ttcatcttca caaatctttt tcattctaag
     4141 ggtcatatct ttaactgtaa ctctcttaaa atcgtatctt tggcatcttg ataaaatggt
     4201 tgcaggtatt ttgtgaggct ctgtagttgc taatataaaa attacatatg atggaggttc
     4261 ctctaaggtc tttaataatg cattaaaagc tccttgagac aacatatgaa cttcatctat
     4321 tatatatact ttatatttag cattggctgg agaatatttc acactttctc taagctctct
     4381 tatatcatct acactattat ttgaagctgc atctatttct acaacatcca ttgtattatc
     4441 ttttaataca gattcgcata tctcacactc attacacggt tcttcattta ttttattcaa
     4501 acagtttact gctcttgaaa aaatctttgc agtagatgtt ttaccagtac ctcttgttcc
     4561 acaaaacaaa taagcatgtc ctatattatc actatatatt tgattcttta aagtcttaat
     4621 aatatgatct tgaccaataa catcttcaaa tttttgtggt ctatatgctc tatataatgc
     4681 tttatgcatc tttttacctc tctttagcaa aattaataaa aaaatccctc attatctaag
     4741 ggattagtct tttatatatt aaatgctgta caccatctat cgacttaatt ccataggcgt
     4801 taccaaaaca gttagctcaa cttaggcacc cccacggcac acaaaagtga tcacttaccg
     4861 ctgcttcctt ccggatctga cggggttcat gagctttcat tgcgcaggac ctaagcatca
     4921 acaccactta tttagggcgg ccctacagaa aataagcctt tagatggaat tcaatcctgc
     4981 tatagcggat tgcaggttac agggcaccgc tacctcccca tctagtacag caaaattaca
     5041 accatattta attactttta ttgtttctgg cggagagagt gggatttgaa cccacgatac
     5101 agttttaccc atatactcgc tttccaggcg agcgccttcg accactcgac catctctcct
     5161 taatctcttt ttctcaatgc cttaaaaaat tcttgcaata tgatcgagca ttcttcttgc
     5221 aaaacatcaa aagctacttt tacattatta ttattaaaat aatctaattt aaactcatgc
     5281 tgtttttcta tatatgaatt ttttacatgt cttgtcccta ttataagctt ttttattcta
     5341 gaattaacta ttgcaccact acacattatg caaggttcca ttgtaacata taaatcacaa
     5401 tcagtcaacc tccaaccacc taatttttct gatgcttgtt ttatcgctaa aatttctgca
     5461 tgtgccgtag agtcttttaa cgtttctgta aggttatgag ctctagctat tattcgatta
     5521 tctttaacta taatagcacc tattggtgtt tcttttttat tatatgcttt atatgcttct
     5581 tttaatgctt ctttcatata aaatgaactt tccataattc ctcccaaaac ttataacaaa
     5641 cttatcttat cataattcat tttataattc aacttaattt tattttgttt atttaattat
     5701 tactatatat agctatattt tttttaaatt agttctaaaa taatttttag atattcatac
     5761 aagagtgttt tataaaaata tttagtgttt tatgatgaaa attctgctgt gtaaattaac
     5821 ataaaaaaac tatgaaatta atatttataa taatttcata gtttttttat ttattgttta
     5881 ctcataatat attctcttca tcaaagcata ctctacatat acaattaata taaatttatt
     5941 ttataacatc aacacccata taaggtctta attcttctgg aactactaca gaaccatctg
     6001 cctgctgata attttctaat atagcagcca aacatcttcc tatcgctaat ccagaaccat
     6061 ttaatgtatg aacatattct gcttttgatt ttttatccct tttaaatctt attcctgctc
     6121 ttcttgcttg gaaatcttca aaatttgaac aagaagatat ttctacatat ctattgtagc
     6181 ttggcatcca aacttctaaa tcatatttaa atgcagctgt aaatcccaaa tctcctgtac
     6241 atatttttac aactctatat ggaagaccta acatttgtaa catagtttca gcatcatgag
     6301 ttaatgattc taattcatta taagaatctt ctggtttaac aaatttaact aattcaactt
     6361 tattaaattg atgttgtcta actaaacctc ttgtatctct tcctgctgaa cctgcttcag
     6421 atctaaaaca aggagtatat gcacagtatt taattggaag ctctgcaaca tctaatattt
     6481 cattagcatg tatattagta acaggaactt cagctgttgg tattaagaaa tactctaatc
     6541 cttctatttt aaacatatct tcttcaaatt taggaagttg accagtccct ataaaactat
     6601 ttctattggc cataaatgga ggtaagactt ccgtatagcc atgcttagct gtatgagtat
     6661 ttaaaaagaa attcattaaa gatctttcta atctagctcc taatccccta tataaagtaa
     6721 accttgaccc agttattttc cctgctcttt caaaatctaa aatacctaga cctgtaccta
     6781 tatcccaatg cgctttatgc tcaaaatcaa atttagtagg ttctccccaa gttcttattt
     6841 gaacattgtc ttcatctgtt tcaccttgtg gtacctctgg atgaggaaca tttggtattc
     6901 tcattaatgt atattccatt tttgcttcta cttcttttac tttctcatca atacctttta
     6961 tcttatctga taactctttc aatcttgcct tttcttctgt tacatctttt ccttctttta
     7021 ttaactgagg tattttttta gaatttacat ttaactcatt tttcataact tcaacttctt
     7081 gaagtatttc tcttctttta ttatctaatt ccactacagc atcaaggtca aattctcttt
     7141 cacctcttct ttccatagct tttttgatat catctagatt ttctcttatt cttttaatat
     7201 ctaacatatt aattcctcct aataattttg ataatataag ttataattcc aacttaattt
     7261 acaaacatta tacttgtaaa ctcttagttt aaacaaattt taaaaataaa aaaagacctc
     7321 cgtttaccct ataaaaggga cgaaaatctt ttatccgcgt tgccacccta attgactata
     7381 ctaaaatgta taatcctctc agacctataa cgtaggtaaa cgtctagctt taactagaag
     7441 ctctagagta gattcaaaaa ccattgtaat gagttttcac catccactca ttctctgaat
     7501 acaatctgtt ttttactatt ttccttcaca gctttttaac taattgtttt atttgataat
     7561 cattatatta tatatattaa catctttcaa tactattatt caaatttttt tagaattttc
     7621 tttaattttt tatattaaat tcattttttc tatttaatta agaccttatc ttttatccat
     7681 tgtatttaga ttacctgtat tattaaataa taatgaagaa ggaacaaatg gaacttttat
     7741 atcattctca tcaaatttat tttttacctt ttccattaca tcaaaatata catcccagta
     7801 atcatcagtt tttacccaag gtctagcaac tatttgcatg gtgttatttc ctatagagtt
     7861 taaacctatt ataggctttg gatcatttaa tattcttttt tcgtttgtaa aaatttcatt
     7921 taatatagac ttaactacat ctatatcact atcatatgaa atattatatg aaaaatctat
     7981 tcttcttttg ttttgatgtg tgtaattaat tatattatta cttgtcagtt gaaaattagg
     8041 tataattata gttttattat ctggcgtctt aagaacagtg ctaaatattt gtatgtcaga
     8101 aactgtacct tctacacctg aaccttgaat ataatcacct atattaaatg gcttaaaaaa
     8161 taaaataatc ataccagagc ctaaatttga taatatttct ttaaaagcta aacctatact
     8221 aaatccagca gctcctaaca cagctacaac tgatgtagtt tgtatcccta taatacctaa
     8281 gcttatcaat gatataatag ataacataga tatatatatt ccatatacaa taaaattatt
     8341 tacaccttta ctcattccat atttgattag aaactttgaa accatccttc ttactatttt
     8401 agatatataa atacctatca caaatacaat tattgcatat ataatatttg gtatattatc
     8461 actaaaatta tcgagcatat tttctaaagt tctcttagtt atattgctat ttgttgaggc
     8521 agtcttagcc aatgataaaa aattcattca actcctcctt atgataatat tccgttgtcc
     8581 tttaactctt ttactatagc ttctatagtt tcttctttta ttgcctcaat tgtatgaata
     8641 tggctacatt ctgtcagaac cgataattgt ttaaattcat ttgtctcaac tttcttcata
     8701 aagttgtcta tatccatttt agaataaata ttaagttctg cagttatctg accatatgtt
     8761 ggatgattta caatgacatc ttttataata ccacctaaat ctacaattat ctttaattca
     8821 tcataaattt ctttagaatc cttatgattt ttacacttta tttgttttgt aaaatacggt
     8881 tgattatata ttatatatcc ttgaggtgta gctattattt caaatcctct agctcttata
     8941 agggctatat cttgaactat tacttgccta cttacattta atagttcagc tagtgttcca
     9001 ccttttacag gatgcttaga ttcttttaaa atatctatta atttacttct tctttcatta
     9061 gaattcatat tacaccttct ttccaaataa aaactttacc tatactatat aattttatat
     9121 tttatcttat tataaatcaa tattgacttt atattctatt taatcttaac ttttataata
     9181 aataaaaaaa ga
//
LOCUS       DAEQAF010000123         8924 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.127, whole genome shotgun sequence.
ACCESSION   DAEQAF010000123 DAEQAF010000000
VERSION     DAEQAF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8924
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.127"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            98..439
                     /locus_tag="KRN00_003265"
     CDS             98..439
                     /locus_tag="KRN00_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBH1829108.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESGNYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            590..1003
                     /locus_tag="KRN00_003266"
     CDS             590..1003
                     /locus_tag="KRN00_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBH1829109.1"
                     /translation="MLELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            1205..1846
                     /locus_tag="KRN00_003267"
     CDS             1205..1846
                     /locus_tag="KRN00_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBH1829110.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            1870..3123
                     /locus_tag="KRN00_003268"
     CDS             1870..3123
                     /locus_tag="KRN00_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBH1829111.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            3169..3819
                     /locus_tag="KRN00_003269"
     CDS             3169..3819
                     /locus_tag="KRN00_003269"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBH1829112.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIGMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            3870..4466
                     /locus_tag="KRN00_003270"
     CDS             3870..4466
                     /locus_tag="KRN00_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH1829113.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            4479..5318
                     /locus_tag="KRN00_003271"
     CDS             4479..5318
                     /locus_tag="KRN00_003271"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBH1829114.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            5558..6712
                     /locus_tag="KRN00_003272"
     CDS             5558..6712
                     /locus_tag="KRN00_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBH1829115.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNPKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            7018..8715
                     /gene="ade"
                     /locus_tag="KRN00_003273"
     CDS             7018..8715
                     /gene="ade"
                     /locus_tag="KRN00_003273"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBH1829116.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKLYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
BASE COUNT         3650 a          858 c         1578 g         2838 t
ORIGIN      
        1 aatatcttaa gtaaatcagt cttacatata tttccgatag attatattga taaaaaacac
       61 taaaattaaa ttaataaaag tacttggagg gatggaaatg aaagaggaaa attttattaa
      121 tgttgaatac gaggataaac gtttttcaat taatagtaaa gaagttttgt acatagaaaa
      181 gcaagagtat gaagtaaaga tttatactga aagtggtaat tatgaagttg gagaaaatgc
      241 tccttgtata agaaaactat tgaaagaaga aaattttttc aaatgcagta atagttatat
      301 tgtaaatcta gacaagtgtg aattttatct cagcaataat tgtatttttg tgaataataa
      361 ttttataaga attttaggtt cagaaagaaa aaagaaatta aaaaagaaat tagaaaaatt
      421 atatgattat gaagattaat attgagaggc tgtattttat acagcctctt tatttattga
      481 ttgtattatt aataaatttt aaattatgat aaaatataaa acaagtaact tatttcagaa
      541 taaaatactt tttaaaagaa agggacgaga tatgggagat tataataaaa tgcttgaatt
      601 aaagaataac ttaggtatca gtgaaagaaa gttaaaatat ccttgtatct ataaacattt
      661 caaagggaaa tattatgcta caatgggtct tagcaaggct attgatgata tagaaaacat
      721 atgtgaaata tatggtaaag aaaatttaat ccaaaacaga aataaatata aattagttat
      781 tagacatact gaaagagaag aagatatcta tgtttatagg gatttagatg gaaactttta
      841 tcataaaaaa gaagaagata ctaatgattt agttttatac aagaccttat atgatgatac
      901 aggaatattt gcaagacctt tggatatgtt tttagaaaaa gtagatacag ataagtatgt
      961 caattcaatt caagaataca gatttgaaga agtatataaa taatataaga gaaatatgtt
     1021 tataaattta gaaaaattct ttaacagtac aataatttgc agaaatacaa atgagattta
     1081 ttgtaaataa tatgttagat tagattataa aatagaaaca aagtaaagta ttatatgata
     1141 taattaagtt ttgagaagtg ataatttata tttaataaaa aataggcata tattaggagg
     1201 acatatggga aatacttttt atatagtaag acatggacaa acggattgga atatattggg
     1261 aaaaacacaa ggtcatggta attctgacct tacgcctcaa ggtatagaac aggcaaaaga
     1321 actttctgaa gatattggca agtattcaat tgattatatt tttagtagcg accttgggag
     1381 agcaatgcaa acagctcaaa ttttaggaga taagctcaat attgaagttc aaaaaactga
     1441 ggcacttaga gaaatgggat tcggagtttg ggaaggcctt ttaataaaag aaattcaaaa
     1501 agattattca gatatatatg caacatggag aaatgaacca cacttagtaa atataccaga
     1561 aggcgaaact cttaagatta taaaggaaag agtagatgct tttataaagg aactaaatga
     1621 aaaatatgat aataaaaata taattcttgt tacacattca attacattga gggttatgtt
     1681 gttgtcattt ttagaatcag gtatggaaaa tatatataga attaagcaag ataatactgc
     1741 tttaaatata gtagaattta aagattatgg gcctgttata gtaaaaatga atgatacaag
     1801 tcatataaaa aatcatgtaa agataaataa ttctgcactg gagtaggaat caattataag
     1861 gagaaattta tgagtaaagt tatagtagtt ggtggaggag cttctggaat gatggcagct
     1921 ttgtcagctt caaaaaacaa taatgaagta atattagttg agagaaatgg agaattagga
     1981 agaaaactta gggcaactgg tggcggtaga tgcaatttta ccaataatag agagatagaa
     2041 gatttttttg ataaagttgt cagtaataaa aaatttctct atagtagttt ttatacattt
     2101 acaaataaag accttatttc gtattttgaa agtagaaatt tggaatataa gattgaagaa
     2161 gaaaatgacc acaaagtata cactaaaaat gataaatcta tagaagtaat agaagtatta
     2221 aataaagatt tactcaatca caatgtaaag ataatgtata ataagaaagt tatagatatt
     2281 ataactgaag aaattgctct aaaagatgat tctaataagg acaagtcaaa gtatctaata
     2341 aaagggatta ttttagataa tggagataaa atactaggag acaaggttat tatatcaact
     2401 ggaggagtga gttattcaaa gacgggttca gatggttcaa tgtataagat tcttaaaaag
     2461 catggacata cattaaacaa actatatcct gctttagttc cacttacaat agaggaaaaa
     2521 tggattaaag atttacaagg aatatccatg aagaatgtgg aaatatcttg taagattaag
     2581 aaaaggaaaa tatcaaaatc tggagacatg ctatttgccc attttgggat aacaggacct
     2641 tgtgttctta taatgtcttc ttatattaac aagattattg aaaaggaaaa ggtagaatta
     2701 aatatagatt tcttaccaaa tttaagtact gatgaaatct ctagtataat cagagcattt
     2761 ccaaataaaa atgttctaaa taatcttaag caaatactac ctcaaaattt cttaaaagag
     2821 attttttctc tattatcttt agttgataaa aaggcaagtg atttgtctaa ggcagatgaa
     2881 attagaatta ttgagtatat aaaaaatatg aagctaactt gtaatgggac tacaggtata
     2941 aacactggta tggttacttc tggtggtatt tcagttaaag aaattaattc ttctactatg
     3001 gaatctaaat tagttaagaa cttatttttt acaggtgaag taattgatat agatgcagaa
     3061 actggtggat ataatttaca aatagcattt tcaactggat atcttgcggg tataagtgta
     3121 taaatataat tttttaataa ttaaatatga ataaatagag gtgtatatat gggtaattta
     3181 gttatagctg tagatggtcc agcaggagct ggaaaaagta caatagccaa gatagtagca
     3241 aaaaagctaa atataaatta tatagataca ggtgctatgt acagagcagt tacttataag
     3301 tgtttaaaaa gtggtattga tgtcaataat gaaaaagaag ttattcaaat agctgaaaat
     3361 tcggatatag attttaaaga taacaatata tatttggaca aagaagttat aaatgaagaa
     3421 ataagaacaa tagaagtaag caataatgtt tctaatgtag caaaaataaa agaagtaaga
     3481 cagttgatgg ttgaagttca acgaaaaata ggaatgaaaa gttcagtaat actagatggt
     3541 agagatatag gttcatatgt tttcccagat gcagattaca aattcttttt agtagctact
     3601 ccagaagaaa gaggaaatag acgctataaa gaactttgta ataaaggata taatactact
     3661 ttagaagaag taattgagga tataataaga cgagatgaaa ttgattcaaa tagagaattt
     3721 gcaccattgg taaaagctaa tgatgcacta gaaatagata ctacaggaaa aactatagaa
     3781 gaagttgtag aagaagttgt atctaaaata aatctttagt tttttatgca tcataatgaa
     3841 aataaatgta gtgttgaagg gagataaacg tgaattttta tagatttgta ataaatattt
     3901 ttaagggttt ttctaaaata ttttttaaat atgaagttat aggtgcagaa aatattccag
     3961 atagaggaaa tatagtaata gcatcaaatc ataaatcgaa tcttgaccct atattcttgg
     4021 ctgctgccat agaaaataga gaaatagctg caattgcaaa gaaagaattg tttaaagtaa
     4081 agccattggg atttatatta aaaaaattgc atgttatgcc tataaataga gaaaaaccag
     4141 atgtatctac aataaaaact attttaaggt cagttagaga tggttatgta ttaggaatat
     4201 ttccagaggg tactagaata aaaggagatt cttttggtaa ggctaaggca ggtctttctg
     4261 tatttacaat aaaaagtaaa tctaaagttg ttccagtatc aataatatct aaatataaac
     4321 tttttagtaa agtaattgta tatattggag aaccaatatc atttgaagaa cattttaagg
     4381 aaaaattgag taatgatgac catgaaagga tatcacaaga gattttagaa gtgataaaac
     4441 aaaattactt taaatattca aaataagggg gtaaagttat gaacataaaa atagcaaaaa
     4501 atgctggttt ttgttttgga gtaaaaagag caatgaaaat ggcatgggat gaagttgaaa
     4561 aaaatgattc tggcatatat gctttaggtc ctcttattca taacaagcaa gcagtagcaa
     4621 aatatgaaga aaaaggtctt aagactgtga atgaaattga tacaatacca aatcatgaaa
     4681 atatgataat aaggtctcat ggagttcctg aaaatatata taaggaagcc aaagataaaa
     4741 aattaaaaat tgtggatact acatgtccat ttgtaaagaa aatacataca gtagtaagtg
     4801 aatatcataa taaaggctat gaaataatag ttattggaga tatgaagcat ccagaagtta
     4861 taggtataaa tggatggtgt gaaaattcag ctataataat aaagacctta gaacaaatgg
     4921 aaaatatgga atttgataac tccaaaaaat attgtcttgt tgcacagact acaataaatc
     4981 cagagttgta tataagtata gttaataaac tatccgataa attagaagaa atagtattta
     5041 atgatacaat ttgttcagct acaaaaacaa gacaagaatc agctaaagag ttagctaaag
     5101 aagttgattg tatgatagtt ataggaggta aacacagttc aaatactcaa aagttagtaa
     5161 aggtttgtga agacttagta ccaacttttg caatagagac taaagatgaa ttggatgtaa
     5221 atacgcttaa aaaatataaa aatttgggta ttacagcagg ggcatctaca cctaattgga
     5281 taatagaaga agttgtaaca ttccttgaaa atttataatt tgataggtaa taaaaatagg
     5341 tggacattgt tataatttat cataatatcc acctttgatt tcatattaca tgtggtaaat
     5401 agataaccta atatcaaaaa gtgtgtatct taagatgaaa aactaagagt ataagatgcg
     5461 cactttttaa tattagaaat tcaaaagaaa tgttgatatt gattatcaat agaaaataga
     5521 atataattgt tgcaaaatta gtctaggagg taaattaatg gaaatgttga tatccgcttc
     5581 tgaagaggcg tttttacatg taggttctat gattggattt tttattttgt tatttggata
     5641 tattaattat aaaactagtg gaaattttac taatatcata tcaaaaaaca gaaaatttca
     5701 accattaata ggtgctttaa ttggagctat accaggttgt ggcggaagtt tggcaataat
     5761 gccattgtat ataaatggaa aattaagctt tggagcaata attgcaagtt taatagctag
     5821 tatgggagat gcagcatttg tacttatttc atcaaatatt aaaatgtatt tttttgtcac
     5881 tatagttagt acaattacag gaataataac tggacaatta gtggattact ttaaactaga
     5941 agaaaaatta gggttaaaaa accgtagaaa atcagataaa tatgatataa gtaaaaataa
     6001 ccctaaagaa aataaagaac aacataatca tgatgaaata attttagaca ctctagctaa
     6061 atctcatgga aatacaaata gacttgcatt tataataaca catggaaagg gatataaaat
     6121 ttatatagga attatagtaa tcggttttat atttatgtca cttgctcact ctggacttaa
     6181 tcttcctata attgagaagt tacattcatt ggaagaagta atagcagtga ttggaatatt
     6241 attttcaata atttatatgt ggtgttttaa aaaggtattt aaaaattcta atcaaaaaga
     6301 ggaagaaaat aaaaagattt ctttgcgaga aatgcttatc cattctgttg gagaaatatc
     6361 atttgtaatt acatggattt ttattgcata tcttatttac gatttgataa tattaatttt
     6421 aggtggagat gaatacttag ttaaattagt attatcaaca ggtgtaataa gtgtatttat
     6481 aggtgcaggt cttggactta ttccaggttg tgggatacaa attgtgctta tgtcatttta
     6541 tttgaaggga actataccac ttggtgcagt gatagccaac tctatttctc aagatggaga
     6601 tgcacttttc ccacttttag caatggataa aaaatcttct ttatgggcta tgattattac
     6661 tactatacca gcaatacttg taggtatgat agtttatgca tttttaggtt aaatataatt
     6721 atgaataaag aagtattaaa aaaataataa agcacataaa tttatttata agaatagtga
     6781 agattaaata taaaaataaa aaattcaata tgaattaaat tattgcttaa atattaatga
     6841 gaacatggga gataatatta ttcctcatgt tctctctatt taattaaagg aattatggaa
     6901 caaatttcaa gtgatacttt ctatcaaaac tcatatataa tatatattaa taaattaaac
     6961 tataatacgt aatacagtca gtatattgat ataaaaaact taggaggagt tgtaaaaatg
     7021 ggtaatttaa aaagacagtg tgatgtttca agtggaagag aaaaagctga cattgtacta
     7081 aaaaatggga caatcataaa tgtatttaca gaagagttaa taacaggaga tgtagcaata
     7141 gtaggagaca ctattgttgg aattggcgat tacaagggca atgtagaaat tgattgtagt
     7201 aacaaatata tatcacctgg ctttattgat gcacatatgc atattgaatc tacaatggta
     7261 atgccaattg aattatcgaa aaaattatta aaatcaggta cgacaactat catagccgac
     7321 ccacatgagt tggtcaatgt aaaaggagct agtgcaatag attttttatt agaatcgaca
     7381 aaagatatac cacttaatgt atatattatg gtgccttcat ccgtacctgc aacaagtttt
     7441 gaaactaatg gagttggtaa atttagtgca aaagacatgg agagttatgt aaataatcct
     7501 agaattttag gtttaggaga ggtaatgtgt tttaatgatg ttataaattc tgaaaatgaa
     7561 atcttggata aactagagct ttttaaaaat aaagttgtag atggacatgc acctaatata
     7621 aatggtaaat cacttcagac atatgtatgt gcaggaatag aaaatgacca tgaatgtata
     7681 acttttgatg aagtatatga aaaattgaga gcaggattaa aaattttaat aagagaagga
     7741 agcgcagcaa aaaatttaaa gtctatagta agtggtatgc taaagcataa cttgccaatt
     7801 gaagaattta tgttttgcac agatgataag cacttagatg atatagaaaa acaaggtcac
     7861 ataagatgga atataaaatg tgcgattgat ttaggtatgg aacctgttag ggctataaaa
     7921 gttgcaactt ataattctgc aaaagcatat gggttaagga aaattggagc aataggtgcg
     7981 ggttataagg cagatattgt tgtattgaat gatttagaca aaatggaagt ggatagtgta
     8041 tataaagatg gtaatttggt aaacgaagag atgttttcta attacaatta tgagattaaa
     8101 gataaagaat tgcttaatac agtcaagttt aaatatatta ataaagaaaa aatacagtta
     8161 aaagtaagtg aaaaaaatta tgtaatggag attgtacctt atcaaatttt gacaaataag
     8221 ttatatgaat ctttaccatg tgcagatgga tattttgttc caaataaaga gtattcaaaa
     8281 ctttgtgttg ttgagagaca tagaatgact ggaaatgtag caattgctcc actaaaagga
     8341 tttggcataa aaaatggagc aattgctact actgtggccc atgattctca taatattata
     8401 gttgcagggg ataatgatga tgatattcta gtagctataa attacttaaa ggaaatacaa
     8461 ggtggttatg taattgtatc aaatggaaaa gttcttgcac acctaagtct tcaagtagct
     8521 ggattaatta gtacttttac agctgaagaa gtacaagaaa ttactgataa tatgttggag
     8581 atagcaagaa aaatgggagt tccagagtat gtagaccctt ttattacact ttcttttatg
     8641 gcacttccag ttgttccaca aataagactt acagatttag gtctatttga tgttgaggaa
     8701 tttaaattta tatagataat ataaaagtaa taataaatga ggctttctca aaatagggat
     8761 aagtctcttt ttattgttga aatgataaaa atatatttga tttcatacaa aaaagagcat
     8821 ctcatgaact aaaaatttta tttttagata tccttatttt aattaatcta tcatttaacc
     8881 ttgttttaag catagatatc ttaataaaac tattttcagt ctat
//
LOCUS       DAEQAF010000124         8894 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.128, whole genome shotgun sequence.
ACCESSION   DAEQAF010000124 DAEQAF010000000
VERSION     DAEQAF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8894
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.128"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(27..635)
                     /locus_tag="KRN00_003274"
     CDS             complement(27..635)
                     /locus_tag="KRN00_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBH1829117.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(744..3482)
                     /locus_tag="KRN00_003275"
     CDS             complement(744..3482)
                     /locus_tag="KRN00_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBH1829118.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRAFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(3630..4421)
                     /locus_tag="KRN00_003276"
     CDS             complement(3630..4421)
                     /locus_tag="KRN00_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBH1829119.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(4457..5113)
                     /locus_tag="KRN00_003277"
     CDS             complement(4457..5113)
                     /locus_tag="KRN00_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829120.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(5106..6071)
                     /locus_tag="KRN00_003278"
     CDS             complement(5106..6071)
                     /locus_tag="KRN00_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBH1829121.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(6177..6283)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(6573..7517)
                     /locus_tag="KRN00_003279"
     CDS             complement(6573..7517)
                     /locus_tag="KRN00_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBH1829122.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNIVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSASIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKRCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            7628..8095
                     /locus_tag="KRN00_003280"
     CDS             7628..8095
                     /locus_tag="KRN00_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829123.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(8265..8864)
                     /locus_tag="KRN00_003281"
     CDS             complement(8265..8864)
                     /locus_tag="KRN00_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829124.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
BASE COUNT         2878 a         1475 c          869 g         3672 t
ORIGIN      
        1 gatacatatc ttacctatat aaaaacttat tctatataaa aacgccataa aaaatctttt
       61 gcttcttctg cataatctat atttatacgt ttactagttt ttatatctaa ctcatcttta
      121 ctaaatactt tttttccttt atcatcataa taaaaatcac ttatatataa ttcttcaccc
      181 attatactct tactatttag acttctatct atttttaaag ctttgcaaag ttttcctggt
      241 ccgttagtaa tattttttac ttgatattta ctcaactcag tgtaagcttt gttgtatcta
      301 ttcatagata tctcatctaa agaagttata ggctctaccc ctcttattaa tacacactct
      361 ggcacatttt ctatatttgc agataaattt aagcaattat acataccata aattaaataa
      421 acatatatat gtccaccatc taaatataat ggcttagttc tatctgtctt tttattgcca
      481 tatacatgtg ctcctttatc atttacaccc atgtatgctt ctgtctctat gattttggta
      541 acaattactt tattttcata tttccttatt agatatttac ctaatattga tttggctaaa
      601 tcaattccat tttttctaaa aaaatccttt tccaaaattt cacctcataa aatttattta
      661 aaacgcatca aatacaacta aagtaataaa taaaattaac tcttattaat gtgatatata
      721 taaacaataa atttagacat ttattattta tatatatcaa aaaattctat ctcaaacttt
      781 tcaatattat cattgtaatt tgaattatca tatacttctt caacaacctc tttaattggg
      841 aatataactt ttacattagt tccttctcct accttactat ctatgtaaat cttcccattt
      901 tgaatttcaa tcaatgattt tgtaaggcat aaacctatac cacttccaaa ttcatttgat
      961 ataccactgt tttcaatttg tttaaatcga ttaaatatat catttaattt ttctttgtct
     1021 atgcccaccc cagtatcttt tataattatc tctactgttt cgtctttttt atatatacct
     1081 acaaggattt ctcctccttc taaagtaaat tttatagcat ttgataatat atttagtatt
     1141 attctttcta tcgattctgg gtcaagccct accataacag tttcttcatc tgtatcaaaa
     1201 attaaatcta ttcctttaga cttagcataa ctactaatag atgtaactat tctttctgtt
     1261 atgtcaataa tatcaaaatt aactgcttta atcttatata tgtctgactt aacttgagaa
     1321 atatttatta tattatctat taatctcaat aatctaaaca tattttgttt agttattttt
     1381 atatgttctt ttagtatatc ctgaaaatca attatttttc cttttttata aaggttttca
     1441 ataagttgaa ctgaactata tatattattt aaaggtgtct taagttcatg agatatatta
     1501 gcataaaact ccatcttcat ttggtcatac tgtctttgtt ttattaatgc ttttttaagt
     1561 ctttcagact ctctttgcac acttaaatct ttaataattc tcactctact tcttttctgt
     1621 ccaaagtata atgttcttga tatcattttt acttctttaa tgtgattatt ttcatttact
     1681 atatggatac tcttctctct ttctcctata tttaaattgt ttatgtattt ttttactaat
     1741 atatttctat atttttgtgt tgtaactcct aatacatcac tagaaattcc gaacaactct
     1801 ctaaaggctc tatttgtata tagtactctt gatgtactta aatcctcaag aaaaatagcc
     1861 tctggtataa catcaagtaa tttttcatat attatttttt gttcatttac tgttctaaga
     1921 atatttatct ctttagttat atctctaaat gtaagcaatt taaagagttt attatctgac
     1981 caatagtctc caactctaac ttcttcaaca tgttcttcac cttctgagtc agacatcaca
     2041 aaattaacta tacagtttgc tgtgtcattg taacttacta tttcagcttt cttttcttgt
     2101 gttagattta atcttttaaa ttccctattg tcaaagaaat ctatgttaaa agtttcaaaa
     2161 tattgttcta atgtcatatc gactaaatca cttgaaacac atttaaaact cttttcatat
     2221 tttttattta tacttattac cttattcttc tttatgccac cctcagcact tcttacaagt
     2281 ataggagatg gaatatttag tataatgttt tcatagtctt tatttatatt tcttatttct
     2341 tcatctattt tgatttcatt tgtaatatca tttaaactta ttaagtaatt gctttcatct
     2401 ttattattac ttaaacttaa caaataaatt ttatcattta actctaccag tttatcaatt
     2461 atacttatat cgttatcaaa tttcttcaat ttttcagcaa ctttttcatc ttcctttata
     2521 aaagttaata ttttataata attattcata tcctttgaaa attcatcttt aaatttatta
     2581 tttgtgtaac ttatattaaa atcatagtct gttactatcc atacatttgg tattgtatcc
     2641 agagcttgtc taagtaattc ttttctctgg tctatgtagt tttttaatgt tctttgtata
     2701 atcatatcct tttctattgc taaatttatc tttcctaatt gctctgactt tttacttaat
     2761 tttttattga ttgaatcaag ttcataatat ggatacacta ctctattatt aagactgtat
     2821 acatatacat aataagtatg gttacataat agtaaatata ttactcctat taatctatct
     2881 gaatctacta tattaatctt agaaattgct acaaaacata taatagttgt aaaaaaaaca
     2941 aaatatgtta aatcttttat taacttatag tgctcaatgt tactatcaag tttattcaac
     3001 aaatatagta aattaaacat agatatacaa atattaatta atataataat catattccag
     3061 ttaatatcac taaaaatatt tcttataaag taatctaata tcacaaaagc actataaaaa
     3121 attagtattg ggcttattct tagttttttt actttagaaa tggttaagta tataaaagta
     3181 gacatattaa ttatgcttaa gttaagcaat acaatttgga atttttgaat ttttaaattt
     3241 actactccta aaatacttac aaaaactaat acaagacacc ctactttcaa tatatttata
     3301 aattcatctg ttttaaagct acttatataa actatagaat atccaaatat ccaaagtaaa
     3361 attattctat acatatttat agaaactgta tacaaattta tatttaaaag tgcaataacc
     3421 aaaaataacc cattagctag tatatagacc ttattcttac ttaaagttcc tttagattcc
     3481 atattcccca ccacttcttc atttttatat agttttacct ataaatatgt taccacaatt
     3541 cttccaaaaa atttgtcact ttctagttat aaaaaaaaat gagtaaatat ttttaatttt
     3601 actcattttg tagattttgt atattcagtt taaaaagctg gaactatact tcctttatat
     3661 tcatcttgta taaatttttt aacttcttta ctattcatag cctctgataa agccttaatc
     3721 ttatcactat ctttattatt ttctctacaa gctattatat ttacatatgg agaatcactt
     3781 gattctatta ctattgcatc cttagtagga tttaagttag ctgttaaagc ataattagaa
     3841 tttattactg ctccgtcaac atcttttaat actgttggta attgctctgc attcatttct
     3901 tttattacta tatttttagg atttttagtt atatcttttt tagttataag ctctccatct
     3961 tttacttcta tcaatttatt ttttgctaat aatttaagtg ctctagctcc attagttgca
     4021 tcatttggca cagctataac agctccatct tttaattcat ctaatgactt aactttttct
     4081 gaatagaatc ccattggctc tatatgaact ttagatgtat aagtaagttt atatcctttc
     4141 tccttcacag tttcctctaa aaatggaata tgttgaaaga agttagcatc caaagaccct
     4201 tcatctaaag ctgtatttgg aagtacataa tcatcaaata tttttacttc taaatcatat
     4261 cctttttctt ttaacaaagg ttttgcaact tccaatatct ttgcatgtgg atttgatgaa
     4321 gctcctacta gtattttttt atcctctttg tttgaacaac ctactgctga tattgctatt
     4381 gctgacacca atgctactga taataatttc tttaatttca tttttactcc ccctctttaa
     4441 aatgtttata attaatttat tttagtttct tataagccag atttcctact ccctggatta
     4501 tctgaactaa tattataagt gctattacag tatataccat tactgctgta tcaaatcttt
     4561 gatatccata aataagtgct atattaccta atcctccagc tcctactgca cctgccatag
     4621 ctgtataacc aagtatagat attattgata atgtaattcc agatactatt gaaggcatag
     4681 cttcctttat cataacttta aatactattt gtctttttgt agctccaaaa gattttgctg
     4741 cttctatcaa tcctttatca acttcattta atgagctttc tataattcta gcgataaacg
     4801 gtgctgcccc aatagttatt ggcactattg cagcagtttc ccctatactt gttccaacga
     4861 ttaatctagt tattggaatc attgcaacta taagtatcat aaatgggaaa cttctaaata
     4921 tatttactat aaatcctaat gcactattta ttgtgctatt tggttttaat ccatctggtt
     4981 ttgtaactac taatatgatt gctaatataa atcctaatat tgttgccact atagttggta
     5041 ctataaccat atacaaagtt tgtaacaatg catttggaaa tagtgttgtt aaaaagtcaa
     5101 ttaaactatt catttatcat ttcctcccat cttatgccct tactagttag atattgtttt
     5161 acttgctctc cacttttatc tgaaatgttt ataataagtg aacctaaaat atcatcttta
     5221 aattgttcta atttcccaaa tattatagac acatctatat ttagttctct tgccatagtc
     5281 gtaataatag cttcattaga aatatcttta gggaatagta tctttatatt tgttcctttt
     5341 ggcaatatta tactttcttc acctattaat tttctaagtc ctttagtatt tcttaagaat
     5401 atttcttctg tatctcctac ctctaatact tctccatttt ccattattgc tactcttcca
     5461 caaatctgct ttataacttc catttgatga gttacaacta ttattgttat tcctaatttt
     5521 ttatttatat cttcaagcaa tgaaagaatt gactttgtag tatttgggtc taatgctgaa
     5581 gttgcttcat cacaaagaag tacttgtgga tttagtgcta aagctctagc aattgcaacc
     5641 ctttgttttt gtccgccact tagatttctg ggtttatcat ttttcttttc agatattcca
     5701 actacttcta ataactctaa aactcttttt ttaatttctg cctttgagta tccaaaacat
     5761 tctaatggca atgctacatt atcaaataca gtttttcttt caagcaatga aaagtgttga
     5821 aaaatcattc ctaactcttt tcttaaatct ctcatttgct tttcattcaa tgactttact
     5881 tctttatcag aaacaagtac actgccttct tggtattctt ctaatccgtt tatacatctc
     5941 agtagtgttg atttccctgc accactatga cctattattc caaaaatttc tccagattct
     6001 atttcaatac ttacatcttt aagcacttga atctttccat aatacttatt aacatttttt
     6061 atgctaatca taaaatttcc tcccatatat tctgctcagt ttttatgttt atcctctctt
     6121 atgtattaca acaaaataaa agcccgagta taaactcagg cttagaaagc tatttatact
     6181 catctatcaa ctatattagt tgcaggattt agcaccaatg tatataaaat atactggttg
     6241 ccgggtttca aagggccagt ccctccacca ctcttgataa gacgttattt aatttaattc
     6301 tattatcatt tgttgctatg ttatatatga tatattcatt aatagtattt gtcaataaat
     6361 ttatttaaat tttttatttt ttattatcgt taattaacta tttttaatta gttttctagc
     6421 tcctaacact ttatatttta atgtctatat aactatagaa catcattata agaaataaat
     6481 taaataacat caatctatct aaatcatctg taaagtaaat taagaaaatt aacattttat
     6541 ccaaactcta tcctactatt aaataaaata atttaaatac aatgatgatt atatagctct
     6601 agtactttag actttatcaa atgtttaagt tctataggtt ctattattgt agcatttttc
     6661 ccaaaagtta aaaaatattc agccacccag ttaagtgtag attttggtat atacatatct
     6721 atgtatccac ctttagacaa gattttcaac cctcttgcca acaaaaattc tgtttcacaa
     6781 cgttttactc cctcatctgt caaattaatt ttaatatgat aatctgtacc tacttccata
     6841 ttcttaagat aatcatgtat agaagataaa accttatatt tcttacttga taagttttct
     6901 atactcaaaa tcttcacaat tctgtctaca cgaaattcct taatagatgc tgattttata
     6961 cagtaagctg gacaatacca aagtccattc atggcataca aaccaatagg aacaatggta
     7021 cgtacactat ttttttgctt tgatgaatat tcaattttaa ttgtagattc attcattact
     7081 atattaaaca attctttcaa taatggtgtt gaacagtgcc tatctggtgt ccaaaaaaca
     7141 aatttacgcc ttatattctc aatattatat tgaatatcat ttggtataca atttaaaaat
     7201 ttttttaaaa cagaaatagt ttcttgctca aatggcaaat cattataata ttctagtgac
     7261 tgatatgcaa agaatataga ttttacctca ctttctgaaa atgcaatcgg tggaagtata
     7321 cgctctttaa gtacatgata tccaccagcc gctccaactt ttgaatataa tggaaatcca
     7381 atactctcca gcacctgtaa gtctcttagt atagtacgtt ttgatacaga aaattcttct
     7441 gctaattctc ctgctgtaaa acttcttttt gcatttattg ttatcatcag ttcaattaaa
     7501 cgctcagctc ttgacatatt tatactccta atttaaatat agtgacaata attgtcacta
     7561 ttatatgata agatattctt acatttaaag caataataat agtaaagaaa gaagggactg
     7621 atactttatg gaaaataata ctattaaggc tgatgatatt atcaattatt gtctatcaaa
     7681 cttagatgat gttttattaa tgaatagttg gggggaacga gcaatttact acaatcctaa
     7741 tggtatttta aagcgaggag tatatgttct taccattaaa gaaaaagaca gtaatcatga
     7801 taaaggttcg ttggttagtc gtccaaatgt ataccgtgtg aatataggat taaaaaaaga
     7861 aacttttatt gaaatgtttg gatatattcc aaagcgtcca ggtgtaggtc aaatagttga
     7921 tatggatttt gattttacaa aattggacac aatcatgcca catcctatct actcatggat
     7981 gggatggata tgtgtcctaa gccctactga aaagacattt gagaacttta aaactttaat
     8041 aggagaatct tacaattttg caaaacaaaa atttaaaaag agaaaaaaca agtaaaaacg
     8101 tgtgaaaata acctctaaat aaattataat aaaaatatta aggttacaag ataaaaatta
     8161 atatcttaat aacatgcaaa aaagcgaagc caaaaaatgt attatttata aggcttcgct
     8221 atatctcaaa taatttattt caaatttcaa aactatttat tctattattt cttattattt
     8281 cctgttattc ctaatctatc attcatatct tttatcattt ttctaaaacc actacctata
     8341 tcatttccaa catcttcagt tccatgaact aattttataa agtcattttg accttttttc
     8401 atatcttcat cagatacctt atctaatttt tctattctct tatctatatc ttttactaat
     8461 ctttcccctt cagcgattag gtcatcattc attttcttta actctgtatc ttctgtttta
     8521 ccatcttttt taagagatgt gacaaatgat tgtattttat ctctactatc tttatatgca
     8581 gcctttacat cacttagata tttttcattt cctggatatt ctttatcttt aaactgatta
     8641 tttatacttt ctggagtatc ataaatagaa tatctattta gacctgctat ataatcatta
     8701 tagcttgttg aataataatt catatatcct tcattattat ttacagattc attaggattt
     8761 tttcctgtat tttcacttgg tttttcatta tttttagtac atgcagttat acctatagct
     8821 aatactagtg ctaatcctac aaataaagtt ctttttaatt tcatttttat taccctccta
     8881 gatattttat acta
//
LOCUS       DAEQAF010000125         8816 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.129, whole genome shotgun sequence.
ACCESSION   DAEQAF010000125 DAEQAF010000000
VERSION     DAEQAF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8816
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.129"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..522
                     /locus_tag="KRN00_003282"
     CDS             <1..522
                     /locus_tag="KRN00_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829125.1"
                     /translation="ALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQMIKSLGINIGSI
                     KILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKKFTFIKDT
                     TAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNISLKKNKCKASTK
                     NKSEKRGVVDVTN"
     gene            509..1264
                     /locus_tag="KRN00_003283"
     CDS             509..1264
                     /locus_tag="KRN00_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1829126.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            1395..2417
                     /locus_tag="KRN00_003284"
     CDS             1395..2417
                     /locus_tag="KRN00_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1829127.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(2581..3138)
                     /locus_tag="KRN00_003285"
     CDS             complement(2581..3138)
                     /locus_tag="KRN00_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1829128.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(3144..4220)
                     /locus_tag="KRN00_003286"
     CDS             complement(3144..4220)
                     /locus_tag="KRN00_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBH1829129.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(4221..4904)
                     /gene="modB"
                     /locus_tag="KRN00_003287"
     CDS             complement(4221..4904)
                     /gene="modB"
                     /locus_tag="KRN00_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBH1829130.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(5053..5865)
                     /gene="modA"
                     /locus_tag="KRN00_003288"
     CDS             complement(5053..5865)
                     /gene="modA"
                     /locus_tag="KRN00_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1829131.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDDGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            6058..6987
                     /locus_tag="KRN00_003289"
     CDS             6058..6987
                     /locus_tag="KRN00_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829132.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(7148..7597)
                     /locus_tag="KRN00_003290"
     CDS             complement(7148..7597)
                     /locus_tag="KRN00_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829133.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(7800..8780)
                     /locus_tag="KRN00_003291"
     CDS             complement(7800..8780)
                     /locus_tag="KRN00_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1829134.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
BASE COUNT         3054 a         1442 c         1076 g         3244 t
ORIGIN      
        1 gccttagctt ttgtattcat ctgtaaagtc cttttagatt tattcctaaa aacaggtctt
       61 ggatacactt taaaaggtgt tggtgataac tctcaaatga ttaaatccct aggtataaat
      121 ataggttcta taaaaatact aggacttatg atttcaaatg gacttatagc tttatctggt
      181 agtcttatgg ctcagttctt gggattctca gatgtaaata tgggtatagg aactttagtt
      241 cttggaattg cctctatcat aattggtatt acactattta agaaatttac ttttatcaaa
      301 gatactactg caataattgt tggctctttt atataccaat tcactatata ctttgcaatg
      361 agtttaggaa tgttatcaac tgacttaaaa ctaataactg ccatagttat aatagctttc
      421 ctagctactg gtaacttaaa tatttcacta aaaaaaaaca aatgcaaagc tagtaccaaa
      481 aataaatcag aaaaaagagg tgttgtagat gttacaaatt aaaaatcttt caaagagctt
      541 ccctaatcca tatggtgaac ctaatactat ctttgaaaat ttatcaatcg atatagaaga
      601 tggtgaattt gtaagtatca taggtagtaa tggaactggt aaatctactt tattaaatat
      661 aatatccggg cttataaaag aatcttctgg tcaagtatta ttaaataaac ataacttgtc
      721 taatttagct gaacacagaa gaactcaaat agtaagtaga gtttttcaag acccaagtct
      781 tggaacttgc ccttctatga ctgttagaga aaacttgtct ttagctctta acaaaggaaa
      841 actattaaat ctaagaaaat gtcttcgtta caaaagagat ttcttagaaa atttattgga
      901 aggtgtatct cttgatttaa aaaaatacct tgatgttcaa gtaaaatttt tatcaggagg
      961 tcaaagacaa tcattatcac taattatgtc gtgcttaaca aatccatcag ttttattact
     1021 tgatgaacat acagcagcac ttgacccaaa aacatcaaat gaagtaattg aattgactaa
     1081 taagattgta agggaaaaaa acataactac acttatggtt actcacaact taaaacacgc
     1141 tcttcattat ggtgatagat tgataatgct tcataagggt gaagttgtat tagatgtaaa
     1201 aggtaaagaa aaagaacaat taacagttga agaaatctta gaaaaatttg aatatgcagt
     1261 ttaaaataat atatctattg tattaaactc ggctttaaaa taaagttaaa attacaataa
     1321 ttatggttac tttgtaataa ttcatatgaa tatatgaaca tatataataa taaatttttg
     1381 agggggatat aaaaatgatt aataaaaaaa gattggcaag tttgatttta gctggtgctc
     1441 ttagtatatc tatgcttaca gggtgttcac aaggaggaga ctctggtaat tcaaaacaag
     1501 aaagtaattc taaaggtaaa gaagttaaaa aaattggtat aactcaactg gttgaacatc
     1561 cagcattaga tgccactagg acaggttttg taaaagcatt agaaaagaac ggatttaaag
     1621 atggagaaaa tattgatata gacttccaaa atgctcaaaa tgacatgcct actacacaaa
     1681 gtattgcgag taaatttgca tctgataaga aggacttaat atttgctata tctactccat
     1741 cagctcaggc agcatttaat gctactaaag atatacctat acttattact gctgtgagtg
     1801 accctgttgc tgctggatta gttaaaactc ttgaaaagcc aggcacaaat gtatctggaa
     1861 catcagattt tgtttctgta gacaaaggtt tagaacttct taaaatattt gctcctaagg
     1921 caaaaactat aggagttatg tacaatacta gtgaagtaaa ttccaaagtt caagttgatg
     1981 ctttaaaaga atatgcatct aaaaatggat ttaaagttgt tgaaaaaggt ataactactt
     2041 caaatgaagt taaccaaggt atttctagtt tagttggcaa aatagacgta ttatatgtcc
     2101 ctacagataa cttagtggct tcttctatgc ctatagtctc taaaatagct actgagaata
     2161 aaatacctgt tatagcagct gaatctgggc cagttgaaaa aggtgctctt gcttgtcaag
     2221 gtatcaacta cgaaaaacta ggttacaaaa caggtgaaat ggcagttaaa attttaaatg
     2281 gcgaatcagt atctgatatg cctgtggcta catcagatga tacagatatc attgttaatg
     2341 aagatatatt aaaagcttta ggtatggaaa aaccttctaa tgaaaatatt tcttatgtaa
     2401 agactaaaca agaatagaaa gatattttct atatacgatt aatatgcctg tttctataaa
     2461 ttaatttata gaaacaggca tatattttta ttttaatgta ttatctattt aaagattata
     2521 tgtaaatgct cttaatttgt ttgtataaat tttacttgta taaactttat acaatcatat
     2581 ttattcttct attttcttta ttactctaca tggatttcca acagctacag tatttggtgg
     2641 tatatctttt gtgactacac ttcctgcacc tattactaca ttatcaccta tagtaattcc
     2701 tggtgttatg attactcccc cacctatcca tacattatca cctattttta caggagaacc
     2761 atactctata cctgaatttc taagttgtgc atcaattgga tgataggctg tatagatttg
     2821 aacgtttgga gctaacatta cattgtcacc tatttcaatt ttacatacat ctaaaaaaat
     2881 acaatcataa tttgcaaaga aattttcgcc tacatgtatg ttatatccat aatcacacct
     2941 aatgttttgt tctacattta tttgcttgcc aactgaacca aatagttgtc ttaaaatatc
     3001 ttctcttttt tcatattcat cctctaaagt attattaaac aatctagtta attttttaca
     3061 atactctctt tcttttacta acaattcatc atttgcatag tatcctttcc cagacaacat
     3121 tttttctttt tcagtcatat agtttactcc tttttgttat aattgtatct aaagcaaaat
     3181 aaatattcct gtggaaaatc taaatatatt ctgtcacctt tcttaaatct cattttactt
     3241 ttttccaatt ctatttgaat aggtacacat tcgttagata aatcagtttt tctaacatat
     3301 atagtatatg taaaaggatt ttctacaatg ttaatcaatt cgaaacataa cttttcattt
     3361 aaatcttcat tagaatccaa gaccttaata tgatgctccc tgattcccac atattctata
     3421 ttatcaccta tttctctatt taatgtcaac tcgcatcccc agtctgtagc ataaatagta
     3481 tttttatcca gtctatttaa tttggatata tttttacacc ctgttatctt agcttctata
     3541 aggtactttg gagattcaaa gagctctttt ttaggtctct ttggaagacc ttctcctttg
     3601 ttgtacacta taatatcatc acaaactcgg taagcttctt caatatcatg agtaacaaat
     3661 agtatatctc ccttgtaatc ttttaacata ttcataagtt ctttttccat attgcttctt
     3721 aaatgatggt ccaatgctga gaaaggttca tctaaaagta atatatctgg agatgttgcc
     3781 aatgctctag ctagtgctac cctttgttgt tgaccaccag ataattgcca agggtatctc
     3841 ccctcaaacc catttaattt aagtatatct aaataccttg ctactatttc ctttttttca
     3901 ctcttactta gttttaaaag cccaagttct atattttgac ttacagtcat atgtggaaac
     3961 aaagcatagt tttgaaataa aaatcctacc tttctatctt gtgttgataa atttatcttc
     4021 ttttcagaat caaatagaac tctatcattt aatacaattt tacctcttgt tggtttctca
     4081 agccctgcta tacattttaa tgtcatactt tttccagaac cagattctcc caaaaacccc
     4141 agagtacctt tttcttgttt aatttctacc tttagtttaa aagaggataa atctttttca
     4201 atatccacgt ataagctcaa ctatccacac ctctttccta taattttctg ctgaaattcc
     4261 gaccaataat ttagtaataa aatcattgct atagatattg ctacaataat cataacccac
     4321 atcatagctt tattcatatc tccgccttca acagcaaaaa atatagctat tggcatagtt
     4381 tgagtttttc caggtatatt tccagctatc ataagtgtag caccaaattc tccaagagct
     4441 ctggcaaacg acagcaccaa tccaccaatt attccaggcc atgctaatgg aactgcaatc
     4501 ttaaaaaata ctttccattc attaagacct aatgttctag cagctgacaa catattatta
     4561 tcaatctgtt caaaagctga ccttgaagtt ctatacatca taggaaaaga caccactact
     4621 gctgaaatta cagttgctgt ccaactaaat attaaagtcc tatcgaaatt taataaaaac
     4681 tttcctataa atccattctt cccacatagt aataataaaa agaaacctac aactgttggt
     4741 ggcaaaatta gtggaagtgt aaatagtcca tctataagac ccttccactt acctctatag
     4801 ttagccataa tatatgacac aaatattcct attacaaaag ttattattgt tgacaaaata
     4861 gatgtcttaa gtgatatcca taagggtgac caatctgttc ccatctttcc ctccttaatt
     4921 ttaaatggaa atagtgaaac taataactct attaatttca ctatttccat tttattataa
     4981 tacacaatta ttttcaattt tcatttattt atatataatt tatacttaat tacacataat
     5041 ttatttctaa gtttattcta cttttttata tccaaattct tcaaaaatct tttgtcctga
     5101 ctcacttaat aaaaattctt caaatttctt agcagcatct acgtttttac tagctttaat
     5161 tactgaaact ggatatgtaa taggtgaatg agttttttcg tctgtttttt caactacttt
     5221 tatcttatca ttattgacag tatcactgaa gtaaacgaat ccaacatcag catttcctga
     5281 ttgcacccat gctaaaactt cttttacatc ttttgcaaat actagcttat cttttaactt
     5341 atcttttaaa tttaaattag ttaacacctc atctgcatac ttaccagctg gaacactttc
     5401 agcttcacca acagcaattt tcttcacttt atctgtagtc aaatctttca tacctgatac
     5461 actactgtca gcagaagaaa taagaactaa atcatttttt actaaatctt tcatagtatc
     5521 agaaactaat aacttctctt catccaaagc tttcatttgt ttttgacctg ctgaaataaa
     5581 taaatcacaa ggtgctcctt gttctatttg ttgttgtaat gagcctgatg ctccatagtt
     5641 aactgtaagt tttacatttg aatcaacttt tttatattct tcttcaatct ttgccattgc
     5701 ttcttttaaa cttgcagcag ccgatatatt taactctact gaatcactac ttttagttgt
     5761 tttttcttgt tttccatcat cttttttgtc ttcattacta ttgcacccaa ctgtccccaa
     5821 agttaaacat gcaactaatc ctaatattcc caatattttt ttcataacaa tctccctttt
     5881 tgtaaatttg atacacattt taacatgttt tattatgttt tatcatgttt tgttatatat
     5941 agtttaatta tatatacatg ataataaatt ttcaagtaat ttatttacac tacttttaaa
     6001 tattttgcta cattttcctt tttttaatgt taaaataacc ttatatggag gtggattatg
     6061 gactcattat catctttgac acctgtcgag gtagctgaat tattaaagat aacaaaaaat
     6121 actgtatatg aattaatcaa aagaggtgaa cttccttctt ataaagtagg gaaaaaaata
     6181 agagttgata ctaaagatgt tgaagaatat atcaacagcc aaaaaactgg taaagtaaag
     6241 gatacacatt tcaacaataa aaatatagat ataaataata atttcaaaat tattatttct
     6301 ggtcaagatg taatattaga cattttagct aggtctgttg aaaaaaaatt ggatggaata
     6361 agtacatttc gctcttatat aggtagttat aatgctttgt atgagttata taatggcaga
     6421 gtttctatag catcatccca tctatgggat ttcgaaacgg atgaatataa tagcactttt
     6481 gttaaaaagc tattgccagg aataccatgt gtacttataa atctagctta tagaatgcaa
     6541 ggtttctatg ttgctaaagg aaatcctaaa gagataacaa cctgggagga tttaacaaaa
     6601 ccaagtataa ccattgtaaa tagggaaaaa ggttctggaa ctagggtttt actagatggt
     6661 aaacttagac ttctaaactt taatggtaaa catataaaag gttatgataa tgaagaatta
     6721 tcacatcttg gagttgcaag tactgtttct cgtggaatag cagatgttgg tttgggaaat
     6781 gaaaaagctg ctttacaagt aaataatatc gactttattc ctcttcacaa agagcgctat
     6841 gatttagtta ttaaaaaaga agacttacaa aatccagttt accaaactat aattaacata
     6901 ataaactctc ctgagtttaa agctgaactt caaggtcttg gcggatatga tttaactgat
     6961 actggaaaaa ctatagcaaa agtttaagat taaaatcgca atctatttta taagatttat
     7021 aatttttcac aaaatttata acttaaacac gaaataaatt gcgattttag tgtctcaaaa
     7081 aatttatgtc tttcatttta tcatccaata caaaatttaa tataattaat tgtgcaatca
     7141 tattatatta atatatattt acataatagt atttttcttt aatgtagatt aacatatgat
     7201 atgttttaaa catcaatccc cttgctttct tatatatatg tggcaacaca tatgagttta
     7261 ataaattata tacaatgtta ctttcttctt gtattttttc aaccaacaag ttatttataa
     7321 aattaccttt ctcattttca ataatctcac tccaatttat cttaactttt aatatatatc
     7381 ttcccactag gtatacacac tctacaataa ataataaaaa tacaatgcag tcagtacctg
     7441 ttgtcttata taaattacct gatactaatg gctttgcgaa gaaattataa aaattcaaag
     7501 tatcacccgt ataatcaaaa agtattaata gcactcctag aactctcaat actttaatat
     7561 tcaacatgtt tttatcttta ttatttttgt ttttcatata tactacctct cttttcttta
     7621 gatttgattg taatctaata ctaactcttt tatttgatgt ataaatgaat ttaattggta
     7681 gttattttca tttttactag aaattaattc acattactaa acaaaactta tatttaaaca
     7741 taaaaatagc ctatctattt tttaataaat acaaaaataa ataagctact aatattcaat
     7801 taacttttat cacttaaaac attactatct ataaatttaa atattttatt gaagtatact
     7861 gtactatcat gttcaaatcc atcaacatga ccaatacctt ctataagcca taggtctttt
     7921 ttatcatgtt taactaaatc atacattttc ttgctatttt gataattaca aacagtatct
     7981 tttgttccat gtataaacag tatgggtaca ttagatttct caaccgactc atatggtttt
     8041 acatcactat accaaaatcc agatttaaac ttattatata aatctccaca agtcaccaca
     8101 taattgatta atatatctgg tattcgtttt tctagtactc ccattctaat tgcatctttc
     8161 atttcagaat aaggagaatc cagtatataa aaatcgacct tatcatcttt tgaatttatc
     8221 tctgaatgca tagcagctgt ccctgccccc atggaaaatc catgcactcc taatctccct
     8281 tcaggaaatt tattttttac aaatttaact agactatcta aatcatacct ttcataaaga
     8341 ccaaatgtgt aattatctcc accactatta ccagtatttc tttgattata aactaataca
     8401 ttataacctt tatctaaata tctatatgct acctttaaca tttcatagta actacttcca
     8461 attccatgaa caagtatcat agtatctctt gtctttatat ttgaagttat aaaaagactt
     8521 tcaagcttgt aattattaga actttgtatc attaattcag atgtcttgta gttttttaat
     8581 ttctccagtg gtttatcttt tctctcagaa aatattttta ctatatcttc gttttttatt
     8641 aactgctcta aaccaactga actattatac actaatttgc caaatatata agatacaatt
     8701 aataggatta atagaaacac aattgatata attataaatt tatttcttaa actaatacaa
     8761 tttttaaaac tatttttcat atttatttac catacaattt tcctatatta tatttt
//
LOCUS       DAEQAF010000126         8738 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.130, whole genome shotgun sequence.
ACCESSION   DAEQAF010000126 DAEQAF010000000
VERSION     DAEQAF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8738
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.130"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            247..2901
                     /gene="adhE"
                     /locus_tag="KRN00_003292"
                     /gene_synonym="adhC"
     CDS             247..2901
                     /gene="adhE"
                     /locus_tag="KRN00_003292"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBH1829135.1"
                     /translation="MAHKEQVIIENKKENEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDVPKKMGAFSQYKYPEALKRYAG
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            3177..5396
                     /locus_tag="KRN00_003293"
     CDS             3177..5396
                     /locus_tag="KRN00_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1829136.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLDEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLKQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFIAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LSEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIQMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRKHGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            5650..6312
                     /locus_tag="KRN00_003294"
     CDS             5650..6312
                     /locus_tag="KRN00_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829137.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRISSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            6683..8092
                     /locus_tag="KRN00_003295"
     CDS             6683..8092
                     /locus_tag="KRN00_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBH1829138.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLTSSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMVNLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            8207..8482
                     /locus_tag="KRN00_003296"
     CDS             8207..8482
                     /locus_tag="KRN00_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBH1829139.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
BASE COUNT         3468 a          896 c         1564 g         2810 t
ORIGIN      
        1 tataaacgtt aaaaaaataa cgttatcctt aagtttttag atgatttcat tagtgatttg
       61 cgtaaaaaat aaagtgatat ctagttaaat taagtatttg taaagctaga tattattagt
      121 agaaatggtg ttatattaga taaaaaataa aatgttaaaa aaataacttg aaaatagaaa
      181 aagtaaatgc tataatgtta ataaattaac ataataaata aaaaactatc tcaggaggtt
      241 gttaaaatgg ctcataaaga acaagtaata atagaaaata aaaaagaaaa tgaagttatg
      301 tcagttggtt tagatactgt aaataacgtt gaaagcttag ttaaaaaact agcaaaaatc
      361 agagaagctc aaaaaatatt tgctacatat agtcaagagc aggtagataa aattttttta
      421 gcagcatctt tggcagctaa taagcaaaga gttcctctag ctataatggc acaaaaagaa
      481 actggtatgg gaattgctga agataaggtt ataaagaatc attatgcctc agagtatata
      541 tataatgcat ataaagaaac taaaacttgt ggtgttatag agaaagacga agcatttggt
      601 atgactaaaa ttgctgagcc aataggtgtt attgcagcag ttgtacctac aactaatcca
      661 acttctactg ctatctttaa agcactttta gctttaaaaa ctagaaatgg aataattttc
      721 tctccacatc caagagcaaa aaattctact atagaggctg caaaagttgt tcttgaggct
      781 gctgttttag ctggagctcc tgaaggtata ataggatgga tagatgagcc atctttagaa
      841 ttaactacaa ctgttatgaa agaagtggat ttgacccttg ctacaggagg tcctggaatg
      901 gttaaatcag cgtattcatc tggaaaacca gctattggag ttggtgcagg taatactcca
      961 gcaataattg atgatagtgc agatataaaa actgctgtaa actcaattct tgtatctaag
     1021 acttttgaca atggtatgat atgtgcttct gaacaatcgg ttatagtatt agaaaatata
     1081 tacaatgaag tcaaaaaaga atttaaagag cgtggtgctt atttattaga taaagatgaa
     1141 acagaaaaaa taagaaatat aattttagta aatggaggat taaattctaa aatagttggg
     1201 caaacagctt gtactatagc aaaacttgca ggctttgaag tcccagtaga tactaaggtt
     1261 ttaataggtg aagtagaatc agttgaaata gaagaagctt ttgctcatga gaaactttca
     1321 ccagtacttg caatgtacaa ggcaagtgat tttgatgatg cagttagaaa agcagaaaaa
     1381 ttagtagaag atggtggatt tgggcataca tcttcattat atattgatga tgtaaatcaa
     1441 agagaaaaac ttgataagtt tacttcagcc atgaaaactt gtagaatttt aattaatact
     1501 ccttcttctc aaggtggtat aggggactta tataatttta aactagctcc ttctcttact
     1561 ttaggatgtg ggtcttgggg tggaaattca gtatctgaaa atgtaggagt taagcattta
     1621 cttaatatta aaacagtagc tgagaggaga gaaaatatgc tttggtttag agcaccagaa
     1681 aaagtttatt tcaaaaaagg ttgtttagga gtagcattaa aagaacttaa agatgtaatg
     1741 aataagaaga gagcttttat tgtaacagat acattccttt ataataatgg atatactaaa
     1801 gcagttactg atttattaga tgaaatgaat attaagcaca ctacattctt tgaagtagaa
     1861 ccagacccaa ctttggaatg tgctaagata ggcgctaaag ctatgagaga atttaatcca
     1921 gatgtaataa tatctatagg tggaggaagt gcaatggatg caggaaagat aatgtggaca
     1981 ttgtatgagc atccagatgt agatttccaa gacctagcta tgagatttat ggatataaga
     2041 aaaagggtat atacattccc taaaatgggt gaaaaagcta attttgtagc tataccaaca
     2101 tcagcaggta ctggttcaga agtaacacca tttgctgtta taactgacca agatacagga
     2161 gtaaaatatc cattagcaga ttatgaactg atgccaaata tggctatagt tgattctgat
     2221 atgatgatga atatgccaaa aagcttaaca tctgcttctg gtatagatgc tttaactcat
     2281 gcattagaag catatgtatc tatgcttgca accgattata caaatggatt agcgttacaa
     2341 gctattaaga gtatatttga atatcttcca cgtgcatatg ataatggtgc aaaagaccca
     2401 gaagctagag aaaaaatggc aaatgcttct acaatggcag gtatggcttt tgcaaatgca
     2461 tttttgggtg tttgtcactc tatggctcat aaattaggtg ctttccacca tgtaccacat
     2521 ggtgttgcaa atgctctttt gataacagaa gttatgaaat ttaattcttc agatgtacca
     2581 aagaaaatgg gagcattctc tcaatataaa tatccagaag cattaaagag atatgctgga
     2641 atagcttcat ttttaggatt aaaaggaaat tctgatgaag agaaattcca aagtttattg
     2701 gtagctattg aagatttaaa acttaaagtt ggtattccta aatctataaa agagtttggc
     2761 gttgaagaat ctaagtttat ggattcaata gatgaaatgg taattcaagc atttgatgac
     2821 caatgtacag gagcaaatcc aagatatcca cttatgaatg aaataaaaga tatgtattta
     2881 aattcatatt atggaagata agtttgctat aaaatagata aaataaaaac tcttatacat
     2941 aaaacaaagt tttattgtat aaggtttttt ttgtttgaga aaatggatag tttttattct
     3001 ttaatttaaa attcaattaa atagtgttat tataataata aaagaatgtt tttatggtta
     3061 ttatgttgat tttatgtgta acatttaaga atagttatat acaatataaa tgatgaattg
     3121 gtataaaaag gatatattat ctatatgaag tattgactaa ttaggggagg agtcgaatga
     3181 cagggagaaa taaaagtttt acattaatta caattctttt tttaacatca ttatttttga
     3241 caatggggta tatctatata gaagatacaa aacatcttct tatgtcagag gcaaaaatac
     3301 atataaaaga agttgcagta caaggctctc aactagcaca aagacaaatt gaaaaagatt
     3361 tagatgtttt aaatattttt tctaactatt atgcttcaaa tccagatata cctaatgagg
     3421 aaaaaatgaa aaatctttta gatgaaatgg aaaatcaaaa attttacact atggcaatag
     3481 ttgatataaa tggtaatgct gaaaatacca aaggtgataa gttttcagtg aaagatagag
     3541 aatttttcaa aaactcaatt aaaggtaaga agtatgtttc aagtccatat gttgatgaag
     3601 taaataagtc tataaagaag attgctattt cagtaccatt attaaataat gataaagtag
     3661 ttggagtttt atattgtact tacaatatca atactctgat gaaacttatt aatatatctt
     3721 tttatgaaaa taatagtata tcttatgttg taaaaaatga tggtacaatt atccttcatc
     3781 cacaagggga tagcctatca aaaaatattt ataaattgtt aaaacaggat aatgatattc
     3841 aagaagtaaa tagattaaaa aaagaattgc aagaaaataa aacaggtgca actgtattaa
     3901 atatgttgga agaaagaaga tatttaggat atgccactat ggataatggg aatagtgaaa
     3961 ataattatat aaaagactgg aatttaattt tttcaattcc agaaactgtt gtatttagta
     4021 attcaaaaca aataatcaac agagctgtat atgcagtgtt atctattgta ttaatattta
     4081 ttgcaattat tttttatata atttatataa aaaaatctaa tgaaaaagaa atattaagtt
     4141 tggcttatga agataaagtt acatatatag gaaatcaaaa taaattttat agagaatgta
     4201 gtaagtatct tttagataaa ccatctttaa attatattat agtatatttt gatattaata
     4261 actttaagat gattaatgat acttttggat atgaatttgg tgacaattta ttaattacaa
     4321 tagcaaaagc tttaaaagaa gaattaacag aaggtgaggt atatgcacga ctttcaagtg
     4381 attattttgc aattttctgt gattataaaa atggaagaaa taaaattata agaaaacttg
     4441 ataatatacg aagtaatatt gaaagtaatt tgagtatagt ctttgaaatt tctctgtgtg
     4501 tgggtattta ttttgttgaa gaaggtgaag tagatattca aaaggctgta aataaagcaa
     4561 atatggctag gtctgttgct aaaggtaaaa atataaatta tgctatttat aatgaagatg
     4621 ttaggaataa gcttagtgag gaatcaatga ttttagatga tataaaaata gcattggtaa
     4681 aaaatcaatt tgaagtgtat tatcaaccta agttttcact tgtaactgga gaaatgatag
     4741 ggagtgaagc actaataaga tggaatcatc cagaacatgg ttttataagt cccgcagtat
     4801 ttattccaat agcagagaaa agtaagttga ttttaaaaat tgggagattt gtatttgaaa
     4861 gggtttgcaa tgatttatct gaatggaaaa agcaaggtaa aaagatagtt ccagtttcag
     4921 taaatttatc tagagtcgag ttgtatcaac cagatattgt aaaatttatc aataaaacaa
     4981 tacaaatgta taatctaagt tcagatttca ttgaaataga gataacagaa actgtggcta
     5041 ttaatgagtt aaatatttta aagaatgttt taaatgaatt gaggaagcat ggattttcta
     5101 tttctatgga tgactttggc acaggatatt cttctattag ttgtttaaga gatatgccaa
     5161 ttgatatatt gaaactagat aagtcttttc ttggtggcat tgaacatgat gagagaagtc
     5221 gcaatatagc aaaatcaata gtgtctctag caaaatcact agatttagtt gtaattatag
     5281 aaggtgttga gagtaaagaa caagctgagt taatgaaaca atttggatgt gatttagtcc
     5341 aaggatttta ttttgcacga ccaatgccag ctaagaattt tttagattta ctttaaaaca
     5401 aaatttgatt tttatataaa gcactattat gaatgcttga ttttgataaa tcattgctaa
     5461 ataattagtg tttttttatt ttatcaatgt attgtctaat ataaagcaaa aaataattgt
     5521 attttataaa aattatatta aaaataaatt tattttgcta ataaacatgt tattaacaaa
     5581 agaatagtac tataatgtat agatgataaa aactttaata aaaatttagt gtataggagt
     5641 tgtttaagta tgatagatgt aagtattgat gacaaactta aggaaagatg gcctaatgct
     5701 aagctgggtt gcattcaagc aaaagtagca gtaaataaaa gctcagaaaa attaattaat
     5761 gaaataaatg agttttgtga tactataaat caaagtctaa aagttgaaga cattacgaaa
     5821 ctagataaaa ttaaagatgc aagaaatgct tataaagagc ttggaaaaaa tccaagtaga
     5881 tatagaatat cttcggaagc attggttaga agaattattc aagggaaggg tctttataca
     5941 ataaataata tagtagaaat aaacaattta atatcaataa aatcattata tccagtaggt
     6001 acatataatg taagcaaatt acattcacca gtatgtttta ctgtaggaga tgaaggagaa
     6061 cagtataagg gcattgggaa agaattaata aatatagaaa atcttcctat attgtctgat
     6121 tcagtgggta aatttgggag tccaactagt gattctgaaa gagcaatgat aacagaagat
     6181 gcaaatgaaa tattaatttg tatattttct tttagtcaag aatctgatat tgaagaatat
     6241 tttggatatg ctaaggaatt acttaaagaa tatgcagatg gaaaagatat agaaactaaa
     6301 ataattaaat agaatctata taacaacgtt atgttaagct aaaattcaat ataaaaataa
     6361 gttaagataa agaaactaac acaaaattag tttctttttt aaaagagtag tttagtgtta
     6421 caaaaataga tagatagtcc cacgattatt aaaagtatgg taatatatta atatagcaga
     6481 gattgtgttt aagggatttt gaaagggggg atttataata atcattttat ctaaaagata
     6541 aaatgatttt atggaaataa ctatatattt aaaaatataa ataatgatac agtaatttgg
     6601 gtatataaaa taaggcatac atggttttgt ttaaaaacca ataaggtaca taggtaatta
     6661 caatgtaagg aaggatttaa ttatgattga tggaaaagag gtaaaacaag aaagtggaca
     6721 aaaaaatcta aaatttaaga tagctatagt agtaggtgtt ttgtttgtag cttatatagg
     6781 aatggcaatc ttttttagaa atcattttta ctttggaacg actattaatg gcgtaaaggc
     6841 ttcaggaaaa acagttgagc aagtaaatga tttgttaaca tctagtacaa attcctatac
     6901 tttaaactta gaggaaagaa acaataagaa agaacaaata aaagcaaaag atattgattt
     6961 aaaatttaca ccagatgata aagttcaaaa gataaaagat agtcagagcg ctattggatg
     7021 gattggtgga atatttaagt ctaaagagta taataatatg gtgaatcttt catataataa
     7081 agatttatta gaaaaaagat ttaacgctct atcttgcttt gatagtaaaa atgttgtaga
     7141 acctaagagt gcttatccta agtatgatag cactaaaaac gcttatgtta tagtaccaga
     7201 ggtacttgga aacaaagtga aaaaagatga tttttataag ttagtacaaa actcaattaa
     7261 ttctgggaat acttctattt ctctggatga aagtaaagtt tatgaagcac caaacaacac
     7321 aaaggattca gaaaagttga aacaagctat taagacatta gataagtatg ttggtgtagt
     7381 cgttacatat gattttagtg accgtaagga aactttagat ggttctgaaa ttaataaatg
     7441 gttaaaagta gactcagaaa agaattatga cataactttt gataatgatg ctatggtaga
     7501 atatacaaga ggtttaagta aaaaatacag tacttttggt gactcaagac catttaaaac
     7561 tgccacaggt aaagatatta caatttcagg tggaatttat ggttggttga tagataaaaa
     7621 gaaagaagct gaagcattag ttgatgttgt aaaagctggt aaaaatgtta caagagaacc
     7681 tatttacata caaaaagctg tatctcgtaa taaagatgat attggaaata catatgtaga
     7741 gattagtctt tctggccaac atatgtggtt ctttaaaaat ggagaaatgc ttgtatcaac
     7801 agacgttgta acaggtgatt tagctagagg atttgctaca ccatcaggta tatatcctct
     7861 taattataag gctagaaatg tttcattaac tggtcaaggt tacagttcac ctgtaagtta
     7921 ttggcttcca tttaatggga acataggcat tcatgatgct acttggagaa attcttttgg
     7981 tggaagtata tataagtctt caggttcaca tggatgtgta aatacacctt tttctaaggc
     8041 aaagaaaata tatgaaaata tagaaccagg tacaccaatt attttatact agtaaatgtg
     8101 ttgctaacag ttaagcgaag tcatcttagt ttatttagga tggcttcctt tttatataaa
     8161 gcttattgaa gtttacagaa agactactta aaaggagaaa tacataatga atgaaaaatt
     8221 aactaaaatt ttagaagaag ctaagaatga tgatgaattt agaaaggaac ttataaaaac
     8281 aagagaacaa cgtgatgtta tggattcatt ttgtaaggtt gttacatcta gaggttatga
     8341 tatgacagta ggggaacttt tttctatggg agaagaatat acatccaatc tactgaaaag
     8401 tgtaaatgga ggagcagcat atcctattga agattggagt gattggtacg aggatttttt
     8461 tataatgttg tcgaatatat agagtaacta atgatattat ctacttaaga ttaatacatt
     8521 gccttaaaat aaaactatta gaactaggtg taagttttat caatctttaa aaatattgat
     8581 ttatttctaa ctagatataa aaaaattaga ttaaaaataa ggtgacaaaa atcgatatag
     8641 cttgatgatt tataaaagtt agataaaata gtgcgagata tttctaaaaa ttcaaaaaaa
     8701 acaataaact tcaatggtta gaggttgaaa aagaatat
//
LOCUS       DAEQAF010000127         8700 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.131, whole genome shotgun sequence.
ACCESSION   DAEQAF010000127 DAEQAF010000000
VERSION     DAEQAF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8700
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.131"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            138..905
                     /locus_tag="KRN00_003297"
     CDS             138..905
                     /locus_tag="KRN00_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBH1829140.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            1188..1385
                     /locus_tag="KRN00_003298"
     CDS             1188..1385
                     /locus_tag="KRN00_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBH1829141.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            1414..2490
                     /gene="vorB"
                     /locus_tag="KRN00_003299"
     CDS             1414..2490
                     /gene="vorB"
                     /locus_tag="KRN00_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBH1829142.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            2493..3212
                     /locus_tag="KRN00_003300"
     CDS             2493..3212
                     /locus_tag="KRN00_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBH1829143.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            3225..3764
                     /locus_tag="KRN00_003301"
     CDS             3225..3764
                     /locus_tag="KRN00_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBH1829144.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            3921..4979
                     /gene="buk"
                     /locus_tag="KRN00_003302"
     CDS             3921..4979
                     /gene="buk"
                     /locus_tag="KRN00_003302"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBH1829145.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            4997..5890
                     /locus_tag="KRN00_003303"
     CDS             4997..5890
                     /locus_tag="KRN00_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBH1829146.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            5920..7128
                     /locus_tag="KRN00_003304"
     CDS             5920..7128
                     /locus_tag="KRN00_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBH1829147.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            7152..8411
                     /locus_tag="KRN00_003305"
     CDS             7152..8411
                     /locus_tag="KRN00_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1829148.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
BASE COUNT         3376 a          963 c         1734 g         2627 t
ORIGIN      
        1 ttattttaca aattaagtat aatatttttg ttttataaaa tataattaag ataaatagat
       61 aattttgtaa ttttaatata taatatttag tagagtgtgg gagtagcact taatatttgc
      121 aggaggagtt tttgtatatg ggagaaataa taaatgcatt agatagagcc ctagacataa
      181 ttttgctgtt atatcatgaa aagagagaaa tgggaataac tgaaataagc aaggctatgg
      241 gagtatataa aagtactgta catagaactt tggttactct tgaaaacaaa ggttttgtta
      301 tacaaaatgc agagaatggt aagtattggc taggaataaa tttatatgca ataggtatgg
      361 ttgtgggaga aaaaatgtca ttgactgaaa tagtaaaacc atatacgaaa aaattaaatc
      421 aagaatttaa cgaagtagtt aatgtatcta tattagaaga aagagctcaa gattctccaa
      481 gaagtatcat aatacataaa gagtatggtt caaatcaatt actttcagta aatccatccg
      541 ttggttcaag tagtgaatgt tattgttcag cagttggtaa atgtcttatg gcatttaatg
      601 attctataga ttttgaaaaa tatagaaaaa caccaataca caagtataca gaacatacaa
      661 ttgataattg ggatgatatg atgctttttt tagcaaaaat aaaagaacaa ggatatgcta
      721 tagatgatga agaactagaa catggactaa cttgtattgg agcacctatc ttagataaaa
      781 ataataaagc tattgcagcc ataagtttgt caggtccaac tataagaatg agagaagggg
      841 actttgagta taagattaaa agagttatag aaactgcaaa aagtatatct gaacttttta
      901 gatgattttt aatctcgata ataaaaatag gctatattta aattgttatt tgtaaatatc
      961 aatttaaatg tagcctattt ttctttaatc taaaattaaa tattcttaaa atttaaaatg
     1021 ttattgaaat atataagcga atgtgttatc ttttaattaa gcaataaaaa tagaacaagg
     1081 ttctatacta tagaacaaaa ttgatgcata tatagtattt atacaaaata taaatattat
     1141 atatttaaaa ttaagtaaaa atattacata aaggggagat ttgagaaatg gaaaaagtca
     1201 agttgagtgt tgaaagatgt aagggatgct atctttgtat tgaagcttgt aaaaaagatg
     1261 caataagtct ttctgactac acaaataaaa aaggctttgt aactattaaa gtcgacgaag
     1321 aaaaatgtat tcaatgtggc gcttgttata caatgtgccc tgatttagta tttgagatat
     1381 tataaattat ttttattaga ggggagaaaa ggtatgcaaa gtttattaat taaaggaaat
     1441 gaagctttag cagaaggtgc tatacgtggt ggctgcagat tttatgcagg ttatccaata
     1501 acaccacaat cagaaatatt agaaatgatg gcatggagac aaaaagaagt tggaggagta
     1561 tttatccaag gtgaatcaga aatagccagt gtaaatatgg ttatgggagc aagtgcactt
     1621 ggagcaagag ctatgacttc ttcatctggt ccaggatttt cattaaaaca agaaggtatt
     1681 gcatattggg tatcagctgg tttgccagca gttgtagcat gtgtgcaaag atatggtata
     1741 ggtgatggat ttataggagc tggtcaagat aattattggc aagcagtaaa aggcggtgga
     1801 aatggagatt atcatttaat cgtgttagca cctaatagtg ttcaagaaaa tatggatatg
     1861 gcatatgaat cttttgaatt ggctgaaaaa tatatgcatc cagtacttat actttctgat
     1921 gctacaatag gtcaaatggt agaaccttgt atagcaccac caatgaaaga atacgatatg
     1981 gataaagctc catgggctgc aaaaggaaca cctgtaggag aaaaaaataa agtaataact
     2041 gatataacat attttgaaga ccaagataca tggcaaaaag ggtatataga aaaaatgaga
     2101 aaagttcaag aagatgaaca aagatgggaa gagatagaaa tagaagatgc tgaagtggta
     2161 tttgtggcat acggtatttc atcaagaata gcagaaggtg cagttagaga tgctagagca
     2221 aaaggaatga aattaggtct aataagacca aaaacattgt ggccttaccc aagaaaagca
     2281 tttaagaaat taagtgattc attgaaggga cttgtaacag ttgaaatgaa catgatggca
     2341 cagatgaagg aagatgtaat tatagcatgt gataatagat ttccagtata ttcagtagca
     2401 acagctcaat atatggcaga agtaaatcaa ttaatagatt ttgctcaaca gattatagat
     2461 ggaaaagcta agcaagagga ggtattttaa ttatggctaa aaaagcacca gcaataatga
     2521 tgtgtgaaaa tatgttctgt ggaggctgtg gacactctat agtcgataga attattggag
     2581 aagtattaac agaaatggat atatgtcaag atacaattat atgttcagat ataggttgta
     2641 atcatatgtt tcaatttagt atgaatgtag atgttgtcgt tccacctcat ggtaaaatgg
     2701 gagcagcaat ggcagctatg aaaagagtta gaccagataa atatatattt acaatagctg
     2761 gagatggtgg agcttatgca atagggcttg gagaaactat gtcagctgct actagaaatg
     2821 ataatgtaat atttcttgtt atgaacaata atatgtttgc aatgacagga gggcaaatgg
     2881 ctccaactac tatagaaggt caatatacag cttctactcc agcgggtaga aattacgcag
     2941 atcatggttc aacatttgat gttgtaaaag ttatgggaaa tttagatata gcatatctag
     3001 caagaggaac aataactaac cctaaagaaa taaatacaac aaaaagatac atcaaaaaag
     3061 ctctagaaaa acaaaaagaa aagaaaggtt tttgcttaat agaagtgctt gtaccatgtc
     3121 caacaaactg gggattaaag ccagtagatg ctatgaagag aattgaaaat gaacttgttc
     3181 caaagtatcc acttggagaa tttattgatt agggaggaaa taatatgttg aatgaaatta
     3241 tatgtgctgg ttttggagga cagggagttc ttacagcagg aaaaattata atgtatgttg
     3301 catataaggc agaaaagaaa attacatggt tcccatctta tggaaatgag atgaggggag
     3361 gaagtgcaaa ttgcaatgtt gttgtaagtg atgaaaaaat tgcaaatcct tgtgtaaaaa
     3421 atccagatat actattggga atgaacagcg tatcagtaga taagtatgaa agtttaatga
     3481 aaaaaaatgg ttatatgttt gtcaatgaat cactagtaag taaggataga aaatacagag
     3541 aagacattaa tgttataaaa gtacctgtta ctgaaatagc acaaaattta ggcaatgaaa
     3601 aagctgctaa catttgcatg ttaggtgcta tggtaaagag tttggattta tttacaaaag
     3661 aagaatttga aagtggcatg tgtgaatact ttgaaaatca aggcaaaggt aaatttaatt
     3721 ctaaaaatgt agaagcattt gaagctggat acgactacga atgaatattt taaatattta
     3781 aaataattat tgaaatactt atttttatat gttagtattt aattaataaa atatagaacg
     3841 tcgttctgga caataggacg aagtctttag gtcggaatac aagaacggcg ttctgtatag
     3901 tagaactagg gggtgttaaa ttgaaagttt tagtaataaa tcctggtggt acatccacaa
     3961 aaatttctgt tttccaagat gaaaatgaaa ttttgaaaaa aaatataacc catacaagag
     4021 aagatttaaa aaatttttct aaagtatttg atgaatatga ttatagaaaa caactgatag
     4081 tagatatttt aagtagtgag aatcatagta taaattcttt tgacgcagta gttggtcgtg
     4141 gtgggcttat gaaggctata aaaggtggta cctatactgt gagtgaagaa atgattgagg
     4201 atatgagaaa tgaaataaat ggggaacatg catcaaattt aggtgcatta ttagctaaaa
     4261 ctatagctga tgaaatagga gtacaatcat ttgtagtaga cccagtttct gtagatgaat
     4321 ttgatgatgt atcgaggatt acaggaatat cagacataga aaaagcaagt tggttacatg
     4381 cattaaacca taaagctgtt tcaagaaaaa ttgcacaaaa actaggggga aaatacgagg
     4441 attataactt tattgtagct catttaggtt caggaatatc gattgtagca cataaacaag
     4501 gcaaaatgat tgatggaagt ggtggtaggt ctgatggtcc attttctcca gaaaggagtg
     4561 gtggattact tgcatatcct cttatagaat tgtgttactc cggaaaatat actcatgatg
     4621 aaatggtcgc aaaagtaagt tcgattgggg gaatgtacga ttatttagga acaaaggaca
     4681 tgatagaaat tgaaaacaga atcaaggagg gtgatgaaaa ggcaaaactt ataatggatg
     4741 catttattta tcaagtagca aaagaaattt ctatgtatgg agcttcactt tcagggaatg
     4801 tagatagagt tatcttgaca ggagggatat ctcactcaga aatggtagtc aaaggagtag
     4861 cagaaaaagt ttcatatcta gctccaatag agatagtacc aggagagatg gaaatggagg
     4921 cacttgctct aggggcactt agagtactta atggagaaga aatagcaaaa acttattaat
     4981 atttaggaga aagagtatgt taaaagattt taataattta ttagaagagg ctaaaaagct
     5041 tgaacctgtt attgtaagtg ttgctgttgc agaagacaaa gaagtattaa aggctgtgaa
     5101 atcagcaaca gatttaaaca ttataaagcc aattcttgta ggagacaagg ataaaataga
     5161 aagtatatca agagaaattg gattaaaagg tcatgaaata ataggttgtc aaaatcccga
     5221 tgaatcagtt aaaaaagctg tagagatagt taaaaataag gaagctaaag ttcttatgaa
     5281 gggattagta aatacaagtg tctatatgag agctatatta aataaagaaa cgggtcttag
     5341 aacaggaaga ttattaagtt tgcttgcagt atatgaatta cctcaatatc ataaacttct
     5401 ttattgtact gatagtggaa taaatgtatc gccaaactta aatcaaaaaa aagatataat
     5461 gacaaatgca cttcttacta tgaaaagtat aggtatggaa aatcctaaaa ctgcgatact
     5521 tactgcaaat gaaatggtag accctaagat acaatctaca gtggatgcca acctacttgt
     5581 agagatggaa aaatcgggag aaataccaaa gtgtatagtg gaaggtccaa tagcatttga
     5641 tgtagcattt gatgcacatg cagcagaaca taaaggtatt aaaagtaata ttgctggtga
     5701 tgttgattta ttagtatttc caaatataga agcagggaat atattaggaa agtcatggct
     5761 tagatttaat aaagctaagt gggcaggtat agttttagga gcaacaaatc cgataatttt
     5821 aggttcacgt tctgacacag ctgaaataaa aataaattca atagcattag cgtgcctagc
     5881 atcacaataa gaaattatta ttaaggagga aaaagtatta tgaaatatgc aaaaagaatg
     5941 gatatggtaa aagcttcagc tataagagat tctcaaaaga aaatagctca gaaggtagca
     6001 agtggtggaa ctgttatatc ttttgctgca gggcttcctg acccaaattt atttccaata
     6061 gaagagataa gtgaaataac tcaaaaagta cttaatgaaa ggggaaaatt tgccctagca
     6121 tatggaccta ctaaaggtga agatgagttg ttagatctat tagtaaaaag aatgaaagaa
     6181 gaagaaaata ttgatacaaa agcagaaaat attataataa ctactgggtc acaacaaggg
     6241 atagcattaa gtgctatgat tttattagaa aagggagatg tagtagttac agaaaatcca
     6301 agttacttag gtgcaataaa tgcatttaga ccttatgaat gtgatttttt aggagtagat
     6361 acagatgaag aaggaatggt aacagatgat ttagacaaat tattatctga aaattctaac
     6421 ataaaggtga tatatgtaat accaacattt caaaacccta caggaaaaac atggtcttta
     6481 caaagaagaa aagattttat ggaagtcgtg aataaatatg atgtcatagt aatagaggat
     6541 aatccttatg gagaaataag atttacacca gaaccgctac ctacacttaa atctcttgat
     6601 actaaagata aagtattgta ccttgggtca ttttcaaagg tattatgtcc aggatttaga
     6661 gttgcttgga tgtgtggtaa tgtagacatc atagataagg cagaactttt aaaacaaggt
     6721 atagatttac agtcaaatca attttcgcaa gtacaagtaa tagaattttt aaagaaatac
     6781 aacttaaatg aacatataga aaaaataaga gcagagtata agaaaagatg tctgctaatg
     6841 ttagatgcta tgaagaaaca tttcccagag gaagctaaat atacagaacc agatggagga
     6901 atgtttatat gggttgaact tcctgaaagt ataaatgtag atgatttatt agataaagcc
     6961 attgatgctg gagttgctta tgtttctgga gagtccttct ttgcaaataa tggtccaaaa
     7021 aatactatga gacttaacta tacaacaatg tcagaagaac aaatcgttaa aggtgttgag
     7081 atacttgcag aagttataaa aaaagaactc aattatgctt gtgaataaat ataaaaagtg
     7141 agggtttaaa tatgggagaa aaagaaaacg gtataaagtt tggaaagtta atgtttcaac
     7201 ttgttattat agcaatatct tgggaattag tttatattat accatttatc caatatacat
     7261 tatatgatcc aatcctaaaa gcattagaat gtacaaacac tcaactaggt tttctactta
     7321 caatttatgg gttaggtaat atatttggag ctcctatagg aggctggtta gcagatagat
     7381 ttgattatag aaagataatt ttaggttctg tatttcttaa tggagtagta tcatttttat
     7441 ttgcatttaa tatgaactat ccatttgcag ttgctacttg ggtaggttgt gcaatcacat
     7501 cattagttat gaactatcct tctatggtaa aaatacttag agttatagga aaagataatc
     7561 aaggtaaggt ttatggattt aatgaagcta tggttggagt ttctggagta gtaatgggag
     7621 caatattctt atatatttat acatgctttg caactcctac attgggtatg agatgggtaa
     7681 tgatatcttt aggaatatta tcaatagcaa tgtgtccagt attatggttt gtaattaaag
     7741 atgtagatat taaagaagaa agagaagaag caggtgaaaa aatgtctgct ggtgatttta
     7801 taacagtact aaaatcacca aatacttggc tagtaggaat aagtatattc tgtgtatatt
     7861 cattcacagt tacaatgtct tattttacac catatataac atctgtactt ggaggttctg
     7921 tagcattatc tggtgcatta gcaataataa gacagcatgg tctaaaatta tttggagcac
     7981 catttggagg atattgtgca gacaaattaa aatctcctac aaaagtactt ttaccaatat
     8041 atgtatttgg tatagcagta atagttttat tcctagtatt acctgcatca actccaatga
     8101 ctatattcat agctttaaca tttgtagtag gtatattagg ttacatggga aaaggtatat
     8161 attatgcagt acaagatgaa gtaaaagttc cagttaaata ttcagcaact actataggta
     8221 tagctgcagc tttaggattt tcaccagatg tattccaatt tgcattaata ggacactgga
     8281 tagatactta tggcaataaa ggttacacat atacatttat attccaaata gcaattctag
     8341 ttattggaat actatcttgt ttatatatat taaaggttaa aaagagaaga gcaagtaaat
     8401 tagaagctta aatattcaat ttggtaatta agtatatata aatacaatac ttattttgat
     8461 gaatgtgatt gtataaataa cataaaaaat atcaatagat taagttttat aataatgttt
     8521 agagaataaa gtataaaaat aaaaatgtta tcaagttttc taggttttaa cataaagtta
     8581 cccctgaagg tgtaaaattg agtggcaatt attatctatt ttcttaccta cataaaccta
     8641 tttaatttaa attctaagag attttcaaaa tagatggtag ttgtactcaa ttttaaacct
//
LOCUS       DAEQAF010000128         8666 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.132, whole genome shotgun sequence.
ACCESSION   DAEQAF010000128 DAEQAF010000000
VERSION     DAEQAF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.132"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..617)
                     /gene="yqeC"
                     /locus_tag="KRN00_003306"
     CDS             complement(<1..617)
                     /gene="yqeC"
                     /locus_tag="KRN00_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBH1829149.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENE"
     gene            complement(800..2077)
                     /locus_tag="KRN00_003307"
     CDS             complement(800..2077)
                     /locus_tag="KRN00_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1829150.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(2216..4522)
                     /locus_tag="KRN00_003308"
     CDS             complement(2216..4522)
                     /locus_tag="KRN00_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBH1829151.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISVYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPVFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(4515..5309)
                     /locus_tag="KRN00_003309"
     CDS             complement(4515..5309)
                     /locus_tag="KRN00_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBH1829152.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(5416..6774)
                     /locus_tag="KRN00_003310"
     CDS             complement(5416..6774)
                     /locus_tag="KRN00_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBH1829153.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     ASGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(8121..>8666)
                     /locus_tag="KRN00_003311"
     CDS             complement(8121..>8666)
                     /locus_tag="KRN00_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829154.1"
                     /translation="EVRQEINIMKEDMSEVRQEMTVMKEDTSEVKQEINVMKKDMSEV
                     RQEITVMKEDVSEVKSEVNFMQNKINNINEDMNGIKDEVSIANEKLYGIEIKIDSLEC
                     EDKSMKEIQIEQNNILGSLLHNSEINKATHDNIEHNIAYIKGDTNSIKEDIAEIRRDL
                     NLVELATSKNWSDIVKLKSVK"
BASE COUNT         2698 a         1579 c          913 g         3476 t
ORIGIN      
        1 ttttcatttt caactttatt aataaataat actctttttc cagaataatt tttaaataat
       61 ccatttggat ttaatactat attttttaag ttttcaatac ttactgtaga actactatta
      121 atactacttg tatctaaatt tgctattttt ttaaatattt ctactctatg tatattctct
      181 tcattaatat tcattccaaa tgatgttata tctaatatcc ctatggtttt tgtagtttta
      241 tgatatacta ctggttcttt agcattccaa cctttaagtt tttttctctt tgagccatct
      301 ccctctatta aaactaaatc aaattggtct acaatttcat ccaaaataga ggaatcaata
      361 cttactaatt tattttcatt atttatataa ctgccacata ctgttattcc atgacaaata
      421 gatggaataa cagttccatc tattgtaata attatattgt cataatcgtt tggtacatat
      481 attttagttg ttgttgtaag gagaactttc aatttatctc tataaaaatt tgcaaaatag
      541 tttataaacg aagtttttcc tcctgctcca actacagtta ttatttcatt cttttctatt
      601 atatttgata gttccacact ttcacctctt ataaccagtt ttctaatctc ttaattatta
      661 tagttagacc tttttagtaa aagtgatttt tgaaattcca taaactcgaa agtaaataga
      721 ttctgttgta aacaacaagg cggatccaat tcgccgctaa gctgtaagct tacgctatca
      781 gtttatcttt taaatataat taagatattc ttactctctg tggttgcttt aatatttgag
      841 gattattctg taaattagat aaattaacta cttgtgattt ttttagtata ttaagactcg
      901 catttacatc tgcatttata atgattccaa cactggattt gtactgtcca cgtgttattc
      961 tttccccttt aaagtcatat tttttaacat tgtccacatt gatatcaggt agaaaatcat
     1021 cagcaaaaaa atctgattta ctagtatagc tttcttcttg cctaataaaa ttgatatttt
     1081 ttattttaca cagatattct aattttcctt ttatctctcc aaatgggatt cttataaaat
     1141 ttctatatat ttttctctcc atattatcac ttttttctaa cttagcatta tatcctacaa
     1201 ttaaatttcc aatattattt tttacacaat aatcaattat ataaaaacag gttttattta
     1261 catagtcttt aacttgatta tttctcttat tccaaacttt aaattgtttt cttgttattg
     1321 cagttatatt cttttttaat tttaaggctt ctattttatc attctgtttg tttgcccact
     1381 gattcacaga ttttagcctt tttccatcta tgataaaact atcacctaaa ttggtaacac
     1441 atgtacataa attttctaaa cccaagtcta tagctagtgc atttttttga tttgaaactt
     1501 cctctgattt tggtatttca taacaatact gaatttcaaa gaacctagct ttatgtttag
     1561 gtattattct tatttcttta atttttttct ctagtatatt ttgtggaact tttatactta
     1621 ctttcccata tagtttttta aatgctggag acataggtac atttaaaatc ccatcttctt
     1681 tgattcttat ttgacctatt attatgctaa aaaacccttc tttatctaaa tatttaggtg
     1741 attttatccc tctaaagtca tattttcctt ctttggctaa tttaattaac ccaaaaaatg
     1801 acctaaacga actgtctact tcttttaata tttgttgcgc tatattacta ttgagaagct
     1861 tatagttctc attttctttg catacatgat aattagcttc atagttaaga tgttctcctt
     1921 gattgaaata atgctgtctt acattatatg taccaacatt atataagttc ttagctaaga
     1981 agcacatctc tcgtagagct tgatattctt ttttagttaa gttttttaat tgttgtctct
     2041 gagttccata gtgtatattt tttattctgt ttgacatgaa ctcacctcct ttagaatata
     2101 ctctactaga cattatatac ggtattttta caaaacacca tatataatgt ccatttaatt
     2161 actttatttt acaaaataat ttaaatttac ttgcttttat acaccttatt atttattata
     2221 attgtttatt attatttttc atacccatat aaactttttc aaaagtcata ggaagctctc
     2281 ttaaacgaac tcctgtagca ttaaatattg catttgctat agctggtgct ggtgtatgta
     2341 taactatttc tcctaatgat ttagcaccat aaggacctcc tgggtcgaaa ttctcagcaa
     2401 aatctaccaa tatatttcca acttcttttt ttgtaggaac tttatactgt aggaaactat
     2461 ctgttaataa tctcccatct ttatcaaata cagggtcttc atacattgca aaccctatac
     2521 ccatcatcac accaccttct acttgtattc tagctaaagt tggatttata actgttccac
     2581 aatcaggtac acatgcaaaa tttatgactt tatattcgcc tgtattttta tctaattcta
     2641 tctctgcaaa tcctgctata aatggtttta tttttttcaa catgccaaaa gattctgttg
     2701 cttccaaaac tactggtaca tcatcactag caaatcctat tcctccaaca gattctctac
     2761 ccaattcctc taatagaaca aacttgctat tatcattttt aacaaaaacc ctgtcttttc
     2821 ccaactctaa atcttctttt ttaaatccta gctttgactc tgcaactgaa agtaatatat
     2881 cttttaattt atttgctgtc tttattgttg catttcctgt aaccgttgtt gtacaagaag
     2941 caaatgctcc tgtatcatag ggacataaat ctgaatcacc tgtataaaca gaaattctat
     3001 ctacagtagt atttaaagct tccgcagcaa tttgagcttg aattgtatca gccccttgac
     3061 ctaagtcagc aagaccagat aatagtttat atgtgccatc ttcatccatt cttatagtga
     3121 ctgttgccat atctacacgt ggtataccag aaccatgatt tgctactgcc atacctactg
     3181 ctcttacttt gttgtttcct atatctttac atggatattt atcatcccaa ttaattaatt
     3241 tctttccctt ttctatacat tgtctcagct cacaacttaa tatttcgtct tcagctgctt
     3301 ttccattggt atacctatct attatatttt taattctaaa ttcaagtggg tccattccaa
     3361 tcttatgtgc caattcatca atagcactat ctattgcaaa tattccctgt gtagcaccat
     3421 accctctaag tgctcctgct ggtaacctat tagtatatac tgttctagca ttaaatctaa
     3481 cagcatcaat atcattatat attggtaagg tattgtgtcc agattcggaa gaaacagaga
     3541 caccattccc accataagca cctgtattgt ttaatgactt tagctctatt gcttttaaat
     3601 ttccttcttt atctgcacca actttaacat caaaaaacat ttcatgtcta ctattagaac
     3661 ctacaaaagt ttcacttctt gtaaatacaa attttgctgg tctaccagtt ttcatagtaa
     3721 caaatgcagt aaatatatct gttgctgcta tattctttcc tccaaatcca ccacctattc
     3781 taggtttaat tactcttatt tttgaagacg gtatacccaa tacttttcta agtattctct
     3841 ttacattgtg tggtgattgt aatgatgaaa ctacaacaat tctatcattt atatctttat
     3901 atgaatatga cctatgagtt tccatcatgc aatgcgattg actttgggtt ttgtatgaag
     3961 attcaaccac aaaatcactt tctttaagct tagcttcaac atctccaaat tcaaaaaatt
     4021 cttttgatac tatattattt tttgcatcca atccaaaagg gtatggctct actatgtctt
     4081 tttctggatg tataacaact tcatttcctt ctgcttctct tgcatcaaac acaggcttta
     4141 aaacctcata atctaccttt atcattttta aggctttaag tgctgttttc tcatcttcag
     4201 cagccactaa agctacttca tctccaataa atctaactgt atcttcaagt aaaactctat
     4261 cataaggtga tgcttctggt tctgtttgac ctggaacaca atatctgacc tgtggtacat
     4321 ctttatacgt ataaataccc acaacccctg gaattttttc ggcttttgat gtatctatat
     4381 tctttatctt agcatgagca tgtggacttc taagtagttt taatgtcaaa acatctttat
     4441 gcataatgag gtcttcagta tatagaggtt ttcctgtgac aattgctgta ctatctatct
     4501 ttcttatccc cttattaatc attatacatt ccctcctcaa tagcattata catcctttta
     4561 actaatgcac ttgccatatc ctttctgtac tctttactag ctctcatatt acttccataa
     4621 gtaagttcct tactagcaac aatagatgcc ttatctatat ctttttcttt atttaatata
     4681 ttactcgctt caagtgctaa tctagctttt tgaggtcttg ccccaattgc tattttgtaa
     4741 gtatcatttt cttttagcat tgctgaattt aatacagaaa aatctcctgt gcattttctt
     4801 attgagtcaa aaacagctat tgcatctttt tttggtagta ttacttcgac caatatatcc
     4861 ctacttaatt cactatccaa aaactcactt aactctagta ttcctttatt gtataatctc
     4921 accttcgctc caacaaccaa aagtgctggt attaagtcag aaaagccata ctttgaaaat
     4981 acacttgcac caattctagc cccttgtcta aattgaacac caactatatt agaaacagca
     5041 cttgaaagta ttccactaca gtaatttttt atagttttat caatttctaa acttctaagt
     5101 gaagtatctg cacctatcaa aatatttttt tcatcctctt ttatataatt tagatttata
     5161 tcttttaaat ctatcgctgt tcctatattt ttattactta attttataaa tccacatcca
     5221 cctaaaataa cattattttt tttagaaatt aaaattttat atgcttcttc taaactctgc
     5281 ggaactgaat attcctttat agtaaccatc ttatcccccc atcattaact tattaaaaca
     5341 caaaagtttt taataaatct tttatttata tttataattg tagtatattt aattcacata
     5401 tattaaacct ttacattata aacttttatt tttatcctca accttatcac ttttatttcc
     5461 aggaaatttt accatatata aagcttgaat tattatggct accattgctc ctgaaactac
     5521 acttgaatct gcaagtaatg tctctataaa ttttggaaat ttttcaagaa cttgaggagc
     5581 taccatgaat ccaataccag aagccataga aagacctaat atcatgctat tttcttgatt
     5641 aaatccatcc atactaacaa gtcttaaacc agatgttgta agagttgaaa atataacgag
     5701 tgttgctcct ccaaccacac agggaggaat tgttcttatt aaattagcta ataaaggaga
     5761 tattcctgcc aaaaataatc caattcctcc aatagctagt acaaatttac ttacaacctt
     5821 tgtattggaa acgattgcag aattttgtcc aaacatcccc attggagttg cagaaaataa
     5881 tgcacctatt gtagagagta ctccatttcc taaaacagca gaagaaagtt cttcatctgt
     5941 tacttgtcta ttaagccctc ctaccgcaga aagtgtacaa gcacccatta tatcagctat
     6001 ctcaactaaa tatattattg aaaacattac aacaacttca agtcttatat ctagcccaaa
     6061 agcaagtggt tttggaagtg caaccaaagt aaactcctga attgaagaaa aatttactat
     6121 acccaaaatt aatgataaaa tgtatccaaa aattatgcta actaatattg atgcatcttt
     6181 aaataatcct tttccatatt tatttaatcc taatatcata agagatacag atattccaac
     6241 tataaaatta attggattcc caaaagtctc attgcccata cccccagcta agttttttat
     6301 agctattgga aaaagtccaa gacccataca tgcaactatt gttcctgata cagctggagt
     6361 aaatataaat cgtatttttt taagaccaaa accaattata attattacta taccagctat
     6421 tatttgagag ccaaataata ctggtagtcc atacttactt gcaacagata ccccagctcc
     6481 tataaacata gctgtagctc ccattataac tggtattcct cctcctaatt taaaaccttt
     6541 aaacaaaggt attggatata attgtaataa agttgataat cctgcaaaaa ctaatgcggc
     6601 ttgaatcaat aatgttgaca tcttatgatt aagtccagat gcatttgcaa tcaatatcgc
     6661 tggtaaacaa ctacctatta ccattgccat taagtgttgt aaccctaaag gtattgcttc
     6721 ctttagtggt ggtattccgt ctaattcaaa ttttgatgta ctttttgctt tcataataaa
     6781 aactcccgtt acataaaact tattgaatta tataaatact taaaaatcta atatattaaa
     6841 ttaatgatgt tcataaatat caactatact ccaacatata tttaagtttt tagtcttaaa
     6901 aaacagatgc aataaattta attattaaca aatacacgta ttctttaatt ttgtatacat
     6961 tatataccat gctttataaa tataagagta ttatagctat gaatttttaa ttttttatag
     7021 taaatttaat tcaatttaaa tctttcaatc ttaatcatta taagttataa gttttcataa
     7081 gtatttacat gtttcaagtt ttaaacattt acctataaac gctactttat agatgtcact
     7141 tcaaatccag tgacctcata ctttcatatg agcgtagact atttcttcat cttcagcatt
     7201 acctgctaag agcaacccgt ttccactatc aatcgcttat agtgtactct ctctcgagat
     7261 agtcgtttga ccttcctatt tctaggcttg gcgaccaaat gtccattttt aagtacttag
     7321 gctctcacca tataccatcc tcactattgt ttctggtttt caccacattc ataaaagttt
     7381 ctttctatct tttattgtag ttgcaaggct ttaggattta ctggttttaa agttgtgtcc
     7441 tacatagatt tctctatgta cggggccaaa agtacaattt atttaacata ctttgcttta
     7501 ccccctgtaa ataatattat ttactctttc actgtttttg ttattaaatt aattaaatat
     7561 caattaatct aagcataaaa taattattta atttaaactc aaaatattta tgaatatttt
     7621 ataatataat tctcataaga cagaaaaact taataagcta tgtatctcag ttgtaccaat
     7681 gtactctcct ttactatatt tgtatctgca acataaaata tacaagtttc tatctattta
     7741 tagatatata tatctataag caaaatagta atattatttt tatagtaaaa attttattca
     7801 tattactatt tataattttt atagagcaat tttagtgcca atatttgcat acatttgtat
     7861 agtataaaat ttttatgttc tcattgataa aattttactt atttcaagcg ttctattaga
     7921 ttttatcatc taaattttag gttttatttt tataaattaa ttgtatttac ataaaaaaaa
     7981 agacctaaaa acaaattttt aacggtcttt tctcaatttt ttattttcat ttctaaaatt
     8041 tataataaat agtaagaaca ctataaattc ttttatataa aattcttagt ttgtggatga
     8101 taaattagtg aattaaaata ctactttact gattttagtt tgacaatatc actccaattt
     8161 ttactagtgg ctaactctac taaatttaag tctcttctta tttcagctat atcctctttt
     8221 atagaattag tgtcaccttt tatatatgct atgttatgtt ctatattatc atgagtagct
     8281 ttatttattt cagaattatg taataaactt cctaaaatat tattctgttc tatctgtatc
     8341 tctttcattg atttatcttc acattctaga ctatcaatct taatttcaat tccatataat
     8401 ttttcatttg ctatggatac ctcgtcctta attccattca tatcttcatt aatgttattt
     8461 attttatttt gcataaagtt tacttctgat ttaacttcgg aaacatcttc tttcattaca
     8521 gttatttctt gtcttacttc tgacatgtct tttttcatta catttatctc ttgttttacc
     8581 tctgatgtat cttctttcat tacagtcatt tcttgtctta cttcagacat atcttctttc
     8641 attatattta tctcttgtct tacttc
//
LOCUS       DAEQAF010000129         8386 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.133, whole genome shotgun sequence.
ACCESSION   DAEQAF010000129 DAEQAF010000000
VERSION     DAEQAF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.133"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            268..1275
                     /gene="asrA"
                     /locus_tag="KRN00_003312"
     CDS             268..1275
                     /gene="asrA"
                     /locus_tag="KRN00_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBH1829155.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVTSKEE
                     V"
     gene            1276..2067
                     /gene="asrB"
                     /locus_tag="KRN00_003313"
     CDS             1276..2067
                     /gene="asrB"
                     /locus_tag="KRN00_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBH1829156.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSIYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            2080..3051
                     /gene="asrC"
                     /locus_tag="KRN00_003314"
     CDS             2080..3051
                     /gene="asrC"
                     /locus_tag="KRN00_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBH1829157.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAIVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEDINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            3108..3884
                     /locus_tag="KRN00_003315"
     CDS             3108..3884
                     /locus_tag="KRN00_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBH1829158.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLVDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     STVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            4155..6173
                     /locus_tag="KRN00_003316"
     CDS             4155..6173
                     /locus_tag="KRN00_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBH1829159.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIVNTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            6388..7245
                     /locus_tag="KRN00_003317"
     CDS             6388..7245
                     /locus_tag="KRN00_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1829160.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            7342..8211
                     /locus_tag="KRN00_003318"
     CDS             7342..8211
                     /locus_tag="KRN00_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBH1829161.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
BASE COUNT         3422 a          757 c         1510 g         2697 t
ORIGIN      
        1 ataaaaaaca aataagattc ttttttattc aaaaaattga gtagatagta gttttattgt
       61 acttaatgat tgtatttaag tgattagatt tgaaatcgaa taatgtagat aataaaaaaa
      121 tattaacaga acttaataaa ttccattaat atttttttta ttatttttga aactgtgata
      181 attatcacgg aagcatagaa aataaagtgt taagatttaa acaagatagc aagtaagtaa
      241 aactaaaata taagaaaggt gataaaaatg aaactaaaat tagattcatc taagttcaat
      301 gaaggtctga attatctaaa aaaagactac aagatatttg caccagtttt aatcccattt
      361 aaaggtactt tttcagatac tgatgttata agatacaagg aggtaaacgc ttttgaagaa
      421 atggaatttg ctaagaaagc aaacttttca ccaaaagaag ttgtacttcc cataaatcaa
      481 gtattgtttt attttactga aaaagagttt aaggaaagcg atttagacaa caagaaaatt
      541 ttaattttct taagagcttg tgacataaat ggtataaaaa gacttgatga aatatatcta
      601 aataatggtg aagaaaaaga ttatttttat aaaaatatca gagataaagt aaagtttgca
      661 cttgtagggt gtaaggaaag ttttagaaac tgtttttgtg tgagcatgga ttctaacaaa
      721 actgataatt attcaattgg attaaatata gaaggagata cactgtactt agatataaag
      781 gatagtgaat ttgaagtatt taatggagaa gcaactgaat ttaatgttga ttatgtaact
      841 gataatttaa tatctgtaga tgtgccagag aatattgatt caaatgaaat gataggaaat
      901 tcaatatggg atgaatatga tacaagatgt ataggatgtg gtagatgtaa ttttgtatgt
      961 ccaacatgtt catgttttac aatgcaggat attttctata aggaaaacga aaatgtaggt
     1021 gagagaagaa gggtttgggc ttcttgtcaa gtagatggat atacagatat agcaggtgga
     1081 aattctttta gaaaaaaaca aggcgaaaga atgagattta aaactatgca taaaatacat
     1141 gattttaaaa aaagattcgg atatcatatg tgtgttggct gtggaagatg tgatgatgcc
     1201 tgtccgcaat acatatcatt ttcaaagtgt atagaaaaaa taaatgattt agtaactagt
     1261 aaggaggaag tataaatgaa cccatatata ccagtaagtg caaaaatact agatatagtt
     1321 aaacatactg ataaagaatg gacttttaga gtaaactgca atacaaaagg tgtattgcct
     1381 ggaaagtttt atgagatatc tatacctaaa tacggtgaaa gtccaatatc agtatcagga
     1441 tatggagagg attatattga ctttacaata agaaatgtag gaaaagtaac tagcgagctg
     1501 tttaattata aagaaggaga ttcttttttt ataagaggtc cttatggaaa tggatttgat
     1561 gtatccattt atgaaggaag agaaattgta gtagtggcag gaggaagtgc attagcccct
     1621 gtaagaggaa tagttgaata tttttataat aataaagaaa aatgcgaaaa gtttaaatta
     1681 atagtaggat ttaaatcacc aaaagatatt ttatttgcag atgatttaaa gagatggagt
     1741 aaaaaacttg atattttagt tactgtagat ggagcagagg aaggatatag tggtaatgta
     1801 ggattagtaa caaaatacat accagaattg gatatgaaag atataaacaa tacttctata
     1861 gttgtagttg gacctccaat gatgatgaaa tttacagtag aagaattttt aaaaagagat
     1921 ttagatgaaa agaacatttg ggtttcttat gaaagaaaaa tgtgttgtgg aataggtaaa
     1981 tgtggacatt gtaaaatgga tgatacttac atatgtttag atggaccagt atttgattat
     2041 tcatatgcta aaaatcttat tgattagggg gtgaagtttg tgataagaga tttaaatacc
     2101 aaaaaagtaa tgaaaaatgc ttatagaatt acaaaaacaa aatatgagac ttctttaaga
     2161 gttagagtac ctggtggtct tattgaccct gaaagtttag ctatagtttc taaaattgca
     2221 agtgagtacg gcaatggaca ggtgcacata actacaagac aggggtttga aatattagga
     2281 ataaatatgg aagatatgga agatataaat aaaattatac aacctgttat tgaaaaaatg
     2341 aatataaatc aaagtgagaa aaacgcaggt tatccagcgg caggtacaag aaatatagca
     2401 gcttgtatag gaaataaagt ctgtccaaag gctcaatata atacaactga atttgctaaa
     2461 agaatagaaa aagctatatt tccaaatgat ttacatttta aagtggcttt aactggttgt
     2521 ccaaatgatt gtataaaagc tagaatgaat gactttggaa ttattggtat ggctttacca
     2581 atatatgaaa aggatagatg tgtaaattgt ggagcatgtg taaaaaaatg ttctaagata
     2641 tctgttggag cattaaaaac agaaaataat aaggtggtaa gagataaaga taagtgtata
     2701 ggctgtggag agtgtgtact aaattgccca acaaatgcat ggactagaga tgagaaaaaa
     2761 tactatagat tagctataat gggtagaaca ggaaagaaaa accctagact agcagaagat
     2821 tttcttttat gggtagatga ggacagcata ataaagataa tacttaatac ttatagatat
     2881 gtagaaaagt atatagataa agatgcacca ggaggaaaag aacatatagg atatataatt
     2941 gatagaacag gatttatgga atttaaaaaa tgggcacttg aaggtgtaga gcttccagaa
     3001 ataactaaaa tgtacgaaaa catatactgg agtggaatta aatatctata aattgagtaa
     3061 aacatatatt tgaataaatt aaaatttaat agaaggaaga gggaattatg cataaagaaa
     3121 ctttggataa attaactaat gcagctataa ataagataaa tttattaaac acaagtaaag
     3181 taaaatattt ggtatcttct gcgtttgcag gactttatgt aggtataggt atacttttga
     3241 tatttactat tggaggactt ttgactgatg caggttcacc tatgactaag atagtaatgg
     3301 ggttatcatt tgcaatagca ctaagtttgg ttataatgac gggaacagag ttatttactg
     3361 gaaacaatat ggttatgtct gctggtatgt taaataaagg tgtaagtata aaagatactt
     3421 ctaaaatatg ggcatacagt tgggtaggta atttaatcgg agctttggtt ttaggcatta
     3481 tatttgtagg aactggtcta gtagacaaag gacctgtagc tgaatttttt gcaaatacag
     3541 cagctagtaa agcatccatg ccatttacag ctcttttctt tagagggatt ttatgtaata
     3601 ttctagtatg tgtatcagtg ttgtgttcgt ttagaactaa tagtgatact gcaaaaataa
     3661 ttatgatatt cttatgttta tttgctttta taacatcagg ctttgagcat agtgtagcaa
     3721 atatgacaat ttatagtgtt tcattatttt caccaacaat aagtacagtt actattggag
     3781 gagctattta taatttagta gctgtaacac ttggaaatat tgttggagga gctttattta
     3841 tgggtcttgg aacttatata ttaggtaaag aaaagcttaa ttaaatttat tgtataaatt
     3901 ataactctct tgataaatac atttttagta ttattgagag agttattttt atatttttga
     3961 aaaaatattt gaaacaaaaa aaatatggga gcatacgaaa atatatcggt tatatataaa
     4021 aaaaatacgt ttatatatga attatatagt tctaaatata aaaaaagtta aagtcctacc
     4081 gtaaaaaagc gcattttgaa taagataaca aatatgataa aattggtctt gttgaaattt
     4141 ttagggggga tatgatgaca aagaaactag taatatcaaa aacaaagttg tttattttta
     4201 taatagcatt tatttctata tttatatatt tatttggaag taaaaataca cttataggtg
     4261 taggtatagt aacagctatg ctaacactct tggaaagaga tttaactatt tctccaatta
     4321 aaaatttact gaagtattta gcaataaata taatcttagg aatactatca ttttttgcag
     4381 tacaaaatat gtatttagga gttttattaa attttatagc attatttata atagggtatg
     4441 tatttagtta tgacttaaaa agagcagtat atgtaccttt tggtctaatg tatatattta
     4501 tggtaagtat acctgtagga aaaagtgaat ttcctatgag attgtcggct ttagctgttg
     4561 gagcagttat aataatgatt gctcaatttg ttatgaatag aaataggatg aaaaatgtcg
     4621 gagataaaga actgatatct atatgtgatg aattattaga aaaaattagt cttttaaaaa
     4681 atactattaa tgatgatagt tctataatta aatctagtat gagaaaaata gatagctgta
     4741 attatagaat aaattctata tctaaaaatt tgaaaatggt tatttttgat aatagaaaag
     4801 atgactttta tatcagcatt agaggtatag acataatgaa tattttattt tcattagaaa
     4861 gaataagttt aatcctggaa agatacaaaa aggatagtaa agaatttgaa gatgaagata
     4921 taaaaaatat tttagaagaa agtagcataa atagtaaatc agatgtttta gttgtagcaa
     4981 cgaaagaaat aaactatatt aagatgtgtt tagaaaataa agataccata actgataaag
     5041 agatattagg atttagagat tatgttattg ctcaggatac taaaaatata aatttaaaag
     5101 aaatttatag tgttttagaa aatttatatg agtttttagt agattataaa aaagtaaaat
     5161 caagagacga aaagaaagct gaaagaaaat caaagatacc tcatgaattt aaacgactat
     5221 caatatataa gaaaaacttt aatttaaatt ctataagatt ttcttatgca gtaaagattg
     5281 ctttagctac agctgtagca ggttttatta tggattattt ccatttaaga gatggaagat
     5341 ggataatgtt aactgtcttt tcattaacac aaccttacgc agaaaattgt atacaaaggt
     5401 ctagaaaaag aatagaaggt acatttatag gagctgtaat atttattgta ttattttcaa
     5461 taataaaaga tagtacatta aggtcgttaa tagttctttt agcagggtat ataaactctt
     5521 atgtagttga ttatagaaaa ttaatggtat gtgtaactgt ttcagctctt ggttcagcag
     5581 tagttatggg agacccaaat gttttaacaa taagcaggat ttcatatgta gcattaggag
     5641 caattattgc attaatagta aataagttta tattaccata tgatgctaaa acaggctatc
     5701 aacatgttat agaaatgtat aaaggaatag ttaaaaatat aattgatgaa gtcaataagt
     5761 ctatagaaaa tgtagctgat gtttactata taaaaaattt attattgata ccatcactta
     5821 ttgaagatag acttatgttg ataaatgcta tatataaaga taaacatcaa gaggattttt
     5881 tagaaaatca gaaattacta ataagtaata tgtataatct atatataaat gttaataaaa
     5941 ataaaataaa agatgaagat gttgaaaaaa tattgagaga tactaattat atttcaaatt
     6001 acaatgtaga taagtatgat gaaggaagaa gtgtaatttt agagagtatt gtaaatacta
     6061 aaagtctagg tgacaagata atatgtctaa acttactgca aactctaaat ggtgtcaaag
     6121 aaatgtatag aataagtaat ataactaaag tttcaataaa agaagcagct tagatattaa
     6181 attatagaat agccatatat ttaaaataaa gtatatggct atttgtttta taaaatacta
     6241 aaagaaaata atatataaaa aacaaaaaac atatatttat gaattttata tgaaaatagt
     6301 taaaatattg atttttttca ttggttgaaa aaacaattta cttaggataa actataatag
     6361 tattcaaata ttatgggggt tagatttatg agtaaagatg taaaggtaaa gcgtaataag
     6421 aaatatgata catttagtat aactatggaa cttgagagac ctttacttta tgatgaggtt
     6481 gagaacaaag atgataaaaa taataataga aaatttaaca taaagaataa gatatttaag
     6541 ggaataggta tactatttgt attgattttg cttggctttt tcatatggat aaataaaaca
     6601 tatgaacctc aaaagctggc aaaagaagct ctagtcagca atagtaaagt tgaagtaact
     6661 gtaaatgaaa acatttcatt tacaccaaaa ggaagaaaag tttctaaagg cttaattttg
     6721 tatccaggag ctaaagtaga aatagaatct tatgctccac ttgcaagaaa aatagcagaa
     6781 agtggatatg aggttgtaat cgtaaagatg ccacttaatc tagctatact tggaactaat
     6841 aaggcacaga aagttatgga ttcttacaac aacatagaac attgggtaat aggaggtcat
     6901 tcattaggag gagttgcagc atcaaatttt gcacgtgata ataaattaat tgaaggcgtt
     6961 gtatttttag cttcttatcc aatgggtgat gagttgaaag aattaggaaa aaaagttata
     7021 tctatatggg ggagcaaaga tggagtagtc aattttaaaa gtcttgtaga atcaaaacaa
     7081 aaacttcctg atgatacaac ttatgttgag attgaaggag gaaatcatgc acaatttgga
     7141 gactatggaa aacaaaaggg agataatgat gctattataa gtcaagaaaa acaacttaat
     7201 attactgcca atagtatcat taaattttta aagaatatat cttaaactaa aatttaaaaa
     7261 atataatttt ataagttatt atttaaagta aatattaata atataataga atgaatattt
     7321 tattacaagg gggattttaa tatggaatac gatatgccac tttacagacc accaagtgag
     7381 gcttatagtc ttataataca agtcacacta ggatgttctc ataacaaatg tacgttttgt
     7441 agtatgtaca aatctaaaaa atttaaaata aagccactag aagtaataaa aaatgaaatt
     7501 gatatattta gaagatatta taaacatgta gaaagaatat tcttagcaga tggagatgca
     7561 ttgataatac caatggagaa attaagagat attattttat atataaaaga agtttttcca
     7621 gagtgtgaaa gaattactat gtacggctct cctaaatcta tagagaaaaa atctgatgat
     7681 gaacttaaag aattaagaaa acttggtgtt aaaatgattt atctagggct tgaaagtgga
     7741 agcaatgaag tattagaaga tattaagaaa ggttttagta gtgaacaatt aataaaagtt
     7801 ggtagaaaag ttaaaaaaag tgggattaaa ttatcagcca ctgtaatagc aggtcttgga
     7861 ggaactaaaa aaacacatca gcatgcagtt gatacaggaa aaatgttagg agcaatttca
     7921 ccagattatg tgggtgtact tagtttaatg gtagaaccta atactgaact ttacgattta
     7981 cttaaggcag gagagtttac aatactagag gataaggctg tgttacaaga aattaaagag
     8041 atgataaaga atatagatgc taatgaaaaa attgtattta gaagtaatca tgcatcaaat
     8101 tatgctaatt taaaaggtgt attacctgat gataaacaac gtctaattga tgaaattgat
     8161 tactatctaa gtaaccaaaa gctaaaaaga gaagaatata gaagactata gtttttgata
     8221 tatcaatcta tattgatagg taaatactaa gattatttag atacaaaaaa tcatgctaca
     8281 ttaatagttg cttactattg atgtagcatg attttttatt aaaaaacaaa atggtatatt
     8341 catataataa tatatcaata ataatgaaaa tgtgaactag tttaat
//
LOCUS       DAEQAF010000130         8285 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.134, whole genome shotgun sequence.
ACCESSION   DAEQAF010000130 DAEQAF010000000
VERSION     DAEQAF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8285
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.134"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            403..1059
                     /gene="nth"
                     /locus_tag="KRN00_003319"
     CDS             403..1059
                     /gene="nth"
                     /locus_tag="KRN00_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBH1829162.1"
                     /translation="MKNESANEKDVNKILDELEKLYPDAKCELNYGTAFELLIATILS
                     AQCTDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKSQKIKDTSEQLC
                     ELYDGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSNRIGIVDEPN
                     PQKTEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCNYYKELNETK
                     "
     gene            1253..1723
                     /gene="trmL"
                     /locus_tag="KRN00_003320"
     CDS             1253..1723
                     /gene="trmL"
                     /locus_tag="KRN00_003320"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBH1829163.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            1759..2607
                     /locus_tag="KRN00_003321"
     CDS             1759..2607
                     /locus_tag="KRN00_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBH1829164.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            2997..4001
                     /locus_tag="KRN00_003322"
     CDS             2997..4001
                     /locus_tag="KRN00_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1829165.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFIGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            4127..5239
                     /locus_tag="KRN00_003323"
     CDS             4127..5239
                     /locus_tag="KRN00_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1829166.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLPTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDLIIAVGARFAEPIKEAATEYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDIEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            5729..6490
                     /locus_tag="KRN00_003324"
     CDS             5729..6490
                     /locus_tag="KRN00_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829167.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            6493..7311
                     /locus_tag="KRN00_003325"
     CDS             6493..7311
                     /locus_tag="KRN00_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBH1829168.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            7491..8093
                     /locus_tag="KRN00_003326"
     CDS             7491..8093
                     /locus_tag="KRN00_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBH1829169.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
BASE COUNT         3480 a          753 c         1515 g         2537 t
ORIGIN      
        1 aaaaaaggaa tagataagaa agatataatt gagaagaaag agataaatct aaaaggaatg
       61 gataagaaag atataattga gaagaaagag ataaataaaa aagaaatgga taagaaagat
      121 ataattgaga aggaagagat aaataaaaaa ggaatgaata agaaagatat aattgagaag
      181 gaagagataa atgaaaaaga aatagataaa atgattggta aaaaagatga gataattgat
      241 gagaaagata tagagaattt tatggatatt gaagaagata aaaaaagtat caaagtaagt
      301 aaaaaaagta ctaaaaaagg tgaaacggag aaaaaaacaa agaagagtag ttctaataag
      361 gctacacaaa aaacaagtaa agaaactaaa agtaagtcta aaattaaaaa tgagtcagca
      421 aatgaaaaag acgtaaataa gattttagac gagttagaaa aattgtatcc agatgctaaa
      481 tgtgagttaa attatgggac agcctttgaa cttttaatag caactatttt atcagcacaa
      541 tgtactgatg taagagtgaa taaagttact tcagagttgt ttaaaaagta caacacagct
      601 agagactttg ctaatttgag cattgaagaa attagtaaag agataaagag ttgtggtctt
      661 tacaaaagca agtctcaaaa aataaaggat acatctgaac agctatgtga attatatgat
      721 ggtgaagtac ctgatagctt agaaaagctt ataaaattac ctggtgttgg aagaaaaaca
      781 gcaggggttg tacttagtaa cgcttttaat catccagcaa tagctgtaga tactcatgta
      841 tttagagtta gcaatagaat aggaatagtg gacgagccaa atcctcaaaa aacagaattt
      901 gcacttatgg aagctatacc aaaagaaaga tggtcacact cacatcatgt attaattttt
      961 catggaagaa gaatgtgtaa agctagaaat ccagaatgtg caagttgccc aataaaagaa
     1021 gattgtaatt attataaaga acttaatgaa acgaaataac ttttagaaag taagttgtac
     1081 aagagggatt ttctgatata ataatacttg tgaaaatgtt agataaaaaa ctattatata
     1141 catgaaataa aaattattat taacattatt ttatataata gtataatatt attgttattc
     1201 tgtttataaa ataaaatttg ataaataaaa gcgatactta gggaggatta aaatgtcatt
     1261 aaatatagta ttagtagaac cagaaatacc tcaaaataca ggaaatataa taagaacctg
     1321 tgcagcaaca ggttcaactt tacatttagt aaaaccactg ggtttttcat tggatgataa
     1381 acacctaaaa agatgtgggc ttgactattg ggatatagct gatatacaat attacgatag
     1441 ctttgaagaa ttacaagaaa agtatccaaa tagtaaatac tttttttcta caacaaaggc
     1501 taaacagtca cattcagatg tgaaatatga agaaaattgt tttatagtat ttgggaaaga
     1561 aacaaaggga ttaccagaac ctttgttgaa agcaaatatg gatacttgta ttagagtgcc
     1621 tatgttggat gttgaaaaag ctaggtcatt aaatttatca aattcagttg ctattgtagt
     1681 gtacgaggct ttaagacaaa taggataccc aaatatgagg tagttttaac aagcctaaat
     1741 gagaaaggag catacttaat gaaaaatcta aagataatct gtgacagttt atcggacgtg
     1801 ccaaaagatt tgttagataa atatgatata gatatagttt cattaacagt tatactggag
     1861 gaaagagaat acaaggatag aattgatata tctggagatg aattttataa aaggcttaga
     1921 gaagaaaatg tatatccaaa aacttctcaa gctacttatg cccaatttaa ggaaattttt
     1981 gagaaatata caaatgagga tagagagata ctttatatag cagggtctgc cacagctaca
     2041 ggtacgtatc aaagtgctgt aatggcaaag aatgatgtag atggtaaaat atatacatat
     2101 gactctaact tgctttgtat gggaactggt ttacttgtaa taaaagcagg agaacttgca
     2161 agtgaaggaa agtctgttgc tgaaatattg cctgttttgg atgaattaaa agagaaggct
     2221 tttgttatat tttcagtaga tacattggaa tatttacaaa agggaggtag aatatcatct
     2281 actaaggcag caataggaag tatattaaat ataaaaccga ttcttgaaat aagagatgga
     2341 ttagtttcgc aaatatctca agtaagagga aagaagaatg taatttctaa gatgatggaa
     2401 ttgataaaat caaattgtgg tgatgattta tcagaccaaa ttgtatatat aggatatagt
     2461 gatgatttta aggaaaaaga acaattatct aaggttatgc aagatgaatt aagacctaaa
     2521 gaaattagat ttttccaaat tggtgtgtgt ataggtgcac atgctggtcc tggtgttact
     2581 ggtatcatat gcttaaaaaa taaataatat atttttggat gacattattt atttttttat
     2641 taaattagga tagaatatta attattgaga tgttaaattg gatttatttt ggatgaaatt
     2701 aagtgttgat atattagatt tagtttgtag ggaagtgtgt aaatagataa gaatctattg
     2761 cacacttttt tatagtaaga tttattaaaa aaatttcaaa atgtacttgt aaattgtata
     2821 taaaaaaatt ataaatagga tgtaaaagta aataggatgt aaaagtaaat aggatgtaaa
     2881 agtaaatagg atgtaaaagt aaataggatg taaaagtaaa taggatgtaa aagtaaatag
     2941 gatgtaaaag taaataggat ataaaaatat cgtaaatgta tgaggagtga aatttaatgc
     3001 gtttcaaaag aatattgata ttgatgttaa ctgtagcaat gatagctgga atgttggttg
     3061 ggtgtgctaa taacccaagc aataatccta gctctagcaa agataataaa agtgatataa
     3121 gcgataaaag taattcaaaa aaatctgtat caatgatact agatattgaa ggaacaaata
     3181 atgaagctat gaataattca gctttattag cattaaacaa tgctcaaaag aaacttaata
     3241 tagatacaaa caaagtggaa tcagatgatt cctcaacttt ttctaatagt atagatattt
     3301 tatgtaatga caattacgat ttaattatag ctgtaggagc tagatttgca aaaccattgg
     3361 agatggtagc caagaaatat ccaaagcaac aatttgcaat tatagactat gagtatgaca
     3421 agcaaccttc taatataact tcaatttctt atgaagataa taaatctgga tatctagctg
     3481 gattaattgc tggaaaaatg actgaaagcg ataaggttgg ttttatagga ggaacaaaga
     3541 gttctagtag agataaattt gaatcaggtt ttagagaggg tgttaaattt tctaatagta
     3601 gtataaagga tatttcagtt gagtatgcag atgtttttaa agatagcaaa tcagtagaat
     3661 ctatagctaa aaaaatgatg gataatggag tggatattat tttttctact actgaagatg
     3721 attcaaaagc tgtaatagat gcagtaaggg caaaaaataa aaaagttata gcaacgaata
     3781 aagaccaaca tgagttagct ccagaaaatg ttataagttc tattgtaaaa gattttgaga
     3841 atcctactta taatctgata caaagttttg taaaaggaaa ttataaaggc ggaaaagtta
     3901 tagaaaacac agttaagtct ggaagtactg ggcttgccca aaatagttct caaaatattc
     3961 ctccagatgt gttagaatat gttaataaga acaataaata atctactata atatccaaga
     4021 atacttatga ctttagttat gaggtgaatt ggatgttata atagacatat atagaaagac
     4081 atatgcagag gtaggtcaga cctatctaaa tcagggagtg aattttgtga aaataaaaag
     4141 gatattgatg gcttgctttg tagtagtttt tacaattttt atattagcta tatgtaattt
     4201 tgattttggg tttgataaag taaataagaa taattctaat atagatagtg ctaaatcgaa
     4261 acagagtgag tctaaaagtt tgccaacttc agcagaaaag gataaatcaa atagtaaaag
     4321 taagaataaa gaagatgaca cagaagatga ttcatatgta agaaaaacta ttggagtatt
     4381 gttagatacc gaaaacttaa ataacgaatc atataataac aatgtactat cagccttaaa
     4441 aagggctgac gaagattttg atgttaggat aaaacttgaa aaaccaaaga cttctaaaag
     4501 ttttaaagag agtatagaaa aactgcataa gtatgaacca gatttgataa tagcagttgg
     4561 agccagattt gcagagccaa ttaaagaagc tgctactgaa tatcccaaac agcaatttgc
     4621 aatagttgac tatacttata aagttcagcc agctaatgta atttctgtat catttcaaga
     4681 taatgttact ggatatttag caggacttat tgcaggtaaa atgactgata ctgggaaggt
     4741 tggttttata ggaggagttg agggttctag tagagataag tatgaatctg gatttagaaa
     4801 ggggcttaaa acttcaaata aagatgctga gttactagtt aagtattcaa atatatttga
     4861 aaaccctgaa tcagctagaa ctattgcaaa ggaaatgaga gattctgata gagatgttgt
     4921 attttcagct acagaggatg atagtaaaag agctattcag gtagcaagag aaaatggagg
     4981 taaagttata gctattaata aagaccaata cgatatggct ccagataatg taataagttc
     5041 aattataaaa gatatagaac aacctgtata tgaactgata aagaacgttg caaaagatgg
     5101 ttttaaggga agtaaagtaa tggaatttaa aataaaagat ggagaacttg gcttgacttc
     5161 aaagagcagt agaaatatac caccagatgt tttggaatac ataaaaaaag agtataacaa
     5221 agtgaaagat acatattaat tattgatgta gaagattata aaaatatact gcttaagttt
     5281 agattggtga taaaaggata tatttattaa atttgtgcta actgtacaaa atatattgat
     5341 taagtttaga ttagtgataa aaagatatat ttattaaatt tgtgttaaca gtatggaata
     5401 tactgcttaa gtttagattg gtgataaaag gatatattta ttaaatttag tctaactgta
     5461 caaaatatat tgattgagtt tagattagca ataaaaagat atatttatta aatttgtgct
     5521 aactgtacgg aatatactgc ttaagtttag attagtgata aaaagatata tttattaaat
     5581 ttgaaccaac tgtacaaagc tatactaatt aagcttagat taactatata aaattataac
     5641 aataagtgtg tgggcagaaa aattctgcta cacactttat ttatattcac ataaaaaatt
     5701 tatcaaaaaa aagaaaaagg agtaaaaaat ggaatttaca agagaaccat ttatactaga
     5761 tgacgatttg tgtctagctt tggtggacaa aagaattagt tatctaatgg aaaatgaatt
     5821 aaaattaaga aatatagaga taataaaaac aatagaatgt aaagaattat atgaaagcat
     5881 aaaatatcac ccggatatat gtatttgtaa tttaggaaaa ggagatataa ttgttgcgcc
     5941 gaatgtatat aatcaataca aagagttatt aagtagatat aaatttaata taattaaggg
     6001 agaagctaat ttattaaata gataccctta tgatatacct tacaatattg cgatagttgg
     6061 tgactatgct atacacaatt ttaagtatac tgacaaagca atattagatt atattgaaaa
     6121 taataaactt aaaaagataa atatagagca gggctattct aaatgctcaa tctgtatagt
     6181 agatagaacg tctataataa catcagataa aggtatttgg aaaagtatga agaatacaga
     6241 aatagagtgt ttattgatag aaaaaggtca cataaattta tttgagatga attatggatt
     6301 tataggtgga tgtacagggt tgatttctaa ggataaacta gctttttgtg gagatgttaa
     6361 aaaacatcct gactatgaac gtataaaaag ttttgtagaa agtaaaaaca aggagatagt
     6421 tacacttagc tgtgaaaatt tactagatat aggttctata gttcctctca tgacaagaaa
     6481 ggagcgataa ctttggttga gaaggataat atttcttcca tgaaattttt gaggaataat
     6541 aatgtaaacg atagattaat atatacgaat gacattgtag aagtagtgat agattctgca
     6601 aagcaagaag tgttaaataa aaaaatactt aatggtacta aagctgaaca aagagcttta
     6661 aatattgatg agatatcaac ggaaataact agtatgataa taagtataat gaaagagaaa
     6721 cttttgaaag aatacattct aaaatgctat gggcgtacat atcctgaaga taaaaataat
     6781 atatacatat attcactgaa catatttgct aaaaaagaga tttttatgag agaaacagta
     6841 tttactaggg tgagaaatta tatagaagaa aatgatttta taaatgtaga aggttttatt
     6901 agatttagaa tgagagaatt tatgaaatat atttctgcta taggtgatat tgcagttgag
     6961 gagtatttaa taaagaaaga ccaagatgaa tttataagag ttttaaaata ctttatagat
     7021 actcaagaag aaaagattga tttgcttaaa gttcatataa tggaagataa tacatttgtt
     7081 ttatacgata aaaatggaaa taagatagac agtatagatg atgaagaaat tataaatatg
     7141 gtaataagag aaaatttaaa ttatgaggac tttttaataa gtaccttatt aactctatgt
     7201 cccaaaaaaa tagaaatatt ggatttgtta aataataatt gctcaaagga aattatagat
     7261 actgtagaag caatttttga aaataaagtt agtataatta tggaaaacta gaatctaagc
     7321 atataaaagc tatccatata aaattaaaaa aattcttttt aaatcgacac aaaagactta
     7381 taattgtata taaagctata gtataactag tgttattaag tataaagaat atctacttga
     7441 ttaatacaat atagctggca aatatacaat tgataaggag taattttata atggataatt
     7501 taattaggat actgatatta gctgttattg gtggatttat aggttatgtt acgaatgtag
     7561 ttgctataag actgatattt agaccaatag agcctattaa aatacctatt ttaaatatag
     7621 aaatagtagg tcttatacca aagagaagag cagaaatagc agcaaatgta ggagaaataa
     7681 ttcaagaaga atttctttct atggacgaaa tacttgcaaa tatcattact gacgaagata
     7741 aggaagaagt tgtaagatac ataaaagcaa gggtaaaaat tataatacat gagaaagttt
     7801 catttatccc gagtggtata aaaaatatga tacaagatta tctaggagag ataattgagt
     7861 ctgaagttaa gcaaagtata gatgaattga gtaaaaatat aataaataaa gcaaatgaac
     7921 gtatagatat acaaaaaatg gtcgaagata agattaatga actagattta tatgaattgg
     7981 aagagataat aataagaata gctaagaaag aattaaaaca tatagagttt ttggggcttg
     8041 tcttagggtt tttaataggt atagctcaag ggttaattac tatgtttatt taaatatatg
     8101 agaagtagca tttatttaag tactaattat atttacctat ttgagtgaat tacttattaa
     8161 taacatttag atattaattg tatttaccta tttgagtaaa ttacttatta atagcattta
     8221 gatattaatt gtatttacct atttgagtga attacttatt aatagcattt agatattaat
     8281 tgtat
//
LOCUS       DAEQAF010000131         8179 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.135, whole genome shotgun sequence.
ACCESSION   DAEQAF010000131 DAEQAF010000000
VERSION     DAEQAF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8179)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8179)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8179
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.135"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            42..1925
                     /locus_tag="KRN00_003327"
     CDS             42..1925
                     /locus_tag="KRN00_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBH1829170.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDSTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKSDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            2150..2830
                     /gene="pgmB"
                     /locus_tag="KRN00_003328"
     CDS             2150..2830
                     /gene="pgmB"
                     /locus_tag="KRN00_003328"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBH1829171.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYIAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNYYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            2827..5112
                     /locus_tag="KRN00_003329"
     CDS             2827..5112
                     /locus_tag="KRN00_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBH1829172.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFYRELDMKNGILNRRFIVNINDKKFEVRVARFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAISHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHTKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLPYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGR
                     PIKIIVYGKKYILEKCIKIDK"
     gene            5337..6230
                     /locus_tag="KRN00_003330"
     CDS             5337..6230
                     /locus_tag="KRN00_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH1829173.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            6673..7164
                     /locus_tag="KRN00_003331"
     CDS             6673..7164
                     /locus_tag="KRN00_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829174.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            7192..8139
                     /locus_tag="KRN00_003332"
     CDS             7192..8139
                     /locus_tag="KRN00_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829175.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQKGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGCIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
BASE COUNT         3459 a          719 c         1390 g         2611 t
ORIGIN      
        1 tttagattat ataaattatt ataaaggagg gaaattttaa aatgtctaat aaaaataaag
       61 aaaatataac tttaagtaat caaatcaaag gaacaattca aaatagttta acaaaagaag
      121 ctatattaca tataccaatg agcaattatg cctatggtta tgatagagaa acactacata
      181 taagacttag aactaaaaaa aatgaagcga aaagagtaat tttacgaata ggagaccaat
      241 atgtgtggga taaaggaggt gcaggaggag gaaatttaaa tgcatctgga gttggttggt
      301 ctggtggaac aaatatagta atgagtaaag aagtagaaac tgaattattt gactattgga
      361 tagctaagtg taagccttta aataaacgct cacgatatgg ctttataata gaaggtcaag
      421 aggaaaaact tttatttaca gaaaaaagaa taatagagtt gggaaatgaa aatgatgaaa
      481 aggaattatg tgaaataggt aatttttttg gatatccata tttaaattat atagatatac
      541 ctaaagtgcc aaattgggtg aaagatactg tttggtatca gatatttcca gatagatttg
      601 caaatggtga cccgtctata aacccagaag gagtagataa atggggagct attccaacca
      661 gagataattt tacaggtgga gatttacaag gtgtgataga acacttagat tatttgagtg
      721 atttgggaat aaacggaatt tacttttgcc ctattacaat tggaaaaacc aatcatagat
      781 atgatacggt agattatatg gaggtagact ctacattagg agataaagag actttaaaaa
      841 aactaataga agaagcgcat aagagaaata taaaaataat gttggatgct gtttttaatc
      901 atataggata ttattctaaa cagtggcaag atgtagttca aaataaggaa aattctcgat
      961 ataaaaactg gttttatata aaagatatga gtaaaattga tactccaata gaacaaatag
     1021 atgaaaaaaa tataccttat gaaacctttg ggtgtgaaaa atatatgcct aaacttaata
     1081 cagaaaattc agaagtaata aaatatttat tggatgtagg caagtactgg atacaggaat
     1141 ttgatataga tgcgtggaga ttagatgttt caaatgaagt agaccatgtt ttttggagaa
     1201 agtttagaga agaagtcaaa aaagtaaaat cagacattta tatattggga gaaatttggc
     1261 atggtagttt accatggcta atgggtgacc aatttgattc agttatgaat tacttgatgt
     1321 cagaagccat gaaaaaattc ttttgtacag atgagataaa cgccgaagaa tttaagtata
     1381 tgataaatga tgtaatggta agttatccaa tacaagttag tgaagttatt tttaatttac
     1441 ttggaagtca cgatactaca agaatattga cttatgctaa tggaaatatt gatagattta
     1501 aacttgcata tatgtttatg tttgtacaaa caggatgtcc ttgtatatac tatggtgatg
     1561 aaatcggaat ggaaggagaa ttaagttcaa tatctgaagg tcaaagaaaa tgtatggaat
     1621 ggaatgaaga aaaatggaat aaggatatat ttgattttat gaagaagatt attagacttc
     1681 gtaaagaaaa taaagaactt aggtctatat caaatgaatg ggtgttagca gataaggaaa
     1741 atggaacgat tatattgaaa aaagaatcta tttctataat aataaataat tcatctaaaa
     1801 atataatttt gacgttacca gattatttag caaataaaaa agtaaaagat ttatatgaag
     1861 aagaaatagt tgatttaaaa gaagaactaa tgttagagaa atacaagttc attattttaa
     1921 aataatacaa aaaagtattt attttagatt tcatgttaaa ttattataca gtttaaacaa
     1981 gtctttataa acgataaaaa aatatggtct acaagtgagt gaattgaaag tagattttaa
     2041 attaaagact gagttagagt agataatttt ataaataata tcttaaatac aagatagaaa
     2101 ataaattgat tattagtcta aaaatttctt gtagaaagag gaaataagaa tgattgaagc
     2161 atttatattt gatttagatg gtgtaattac agatactgca tattatcact atatagcttg
     2221 gagaaaacta gcccataaag ttgggataga tatagacaca aaatttaatg aatctttaaa
     2281 aggcataagt agaatggagt cattggacag gatattagaa tttggaaata agaaatattc
     2341 attttcagaa gaagaaaaag tgagaatggc tgaagaaaaa aattattact atgtatcatt
     2401 gatagatgag ataacttcaa atgatatttt gccaggcata gaaagcttgt taattgatgt
     2461 aaaatctaat aatataaaga taggtctatc ttctgcaagt aagaatgcaa taaatgtatt
     2521 aaatcatttg ggtataagtg acaaatttga ttttatagct gatgcaggaa aatgtaaaaa
     2581 caataaacca catccagaga tatttcttat gtcagcgaaa gggcttaatg taaatccaca
     2641 aaattgtata gggatagagg atgcaagtgc aggtatagac gctataaact cagctaatat
     2701 gttttctgtt ggtgttggaa attatgaaaa cttaaaaaaa gcaaatttag ttgtagattc
     2761 aacaaatcaa ttaaagtttg aatatataca agaaaagtat aatgagtata tagttaggag
     2821 aattatatga aatgtttatt tagtaatgta gatgagtgga agattataca agataagatt
     2881 gaaatcaaag aaaatagatt agcagagtcc ataatgagta taggcaatgg atatatgggt
     2941 atgagaggaa actatgagga aaattatagt ggagatacac acaaggggtc ttatatagct
     3001 ggagtatggt ttccagataa aactcgtgtt ggttggtgga aaaatgggta tccagaatac
     3061 tttggtaaaa ttcctaattc agtcaactat ataggtgtaa gaattttcat agatgatgta
     3121 gaattagatt tagcaaaatg taaagtagaa gatttttata gagaattaga tatgaaaaat
     3181 ggtattttaa atcgtaggtt tattgtaaat ataaatgata aaaaatttga agttagggtt
     3241 gctaggtttt taagtatatc tgttaaggaa cttgcagtaa ttaaatacag tataaaatca
     3301 ttaaattcta atactaaaat aaaatttgta ccatatttag attcaaatat aaaaaatgaa
     3361 gattcaaact atgaggaaaa gttttggaat ggaatttctt caagttcttt agaatataaa
     3421 gggagtattc tttctcgaac aaaggagaat gcatttaata caccagtatt cactgtgggt
     3481 tcaatgatgt atattaagac aaatggtgat gtagaagcta tatctcatga gagtgattat
     3541 aattactgtg aaaattcgat aacaatggat gttttaaaaa atgaggttgc aagtatagaa
     3601 aaatatgtat ctataacttc aactagagat tataaggaaa gtgagctatt aagaaaatgt
     3661 gaagacattt taaatagaga actatctaaa agttatgatg atatattaaa tgaacataca
     3721 aagttatgga ataaaagatg ggaaagtgca gatgtaaaaa taaatggaga taaaagtagc
     3781 caacaaggta taagatataa tttattccaa ctattttcaa catattatgg agaagattcg
     3841 cgattaaata taggtccaaa aggatttact ggtgaaaagt atggaggagc tacttattgg
     3901 gatacagaag cattttgtgt tccagtatat ctaggtgtag cagataagga ggtaactaga
     3961 aatcttttag aatataggta caatcagtta gaacaggcaa aggataatgc aaaaaaacta
     4021 gggcttaaag gtgctttata tccaatggta acatttgatg gagtagaatg tcataatgaa
     4081 tgggagataa catttgagga aatccaccga aatggaagta tagtatatgc aatatataac
     4141 tatacaaatt atacaggtga ctataaatat ataaaagaaa aaggaataga tgtaataata
     4201 gaaatagcta gattttgggc aagtagagtt catttgtcta caaaaaaaga tttgtatatg
     4261 atacatggag taacaggtcc aaacgagtat gaaaacaata tcaataataa ttggtatact
     4321 aattatatag ctaaatggtg tttagattat gctgtagaaa atatcttacg attagagaaa
     4381 gagtgtaatg aatgtattga cagaaataat gtgactaggg aagaagttga gttttggaaa
     4441 ataatatcaa ataaaatgta tctgccgtat gatgaggaac tacaaataat aattcaaaat
     4501 gataattttt tagataaaga atttgtagaa gtaaaggatt taccaaaaga aaattttcct
     4561 cttaatcaaa attggtcttg ggataagatt cttaggtcgt gttttataaa acaagcagat
     4621 gtattacagg gaatttacta ttttggaaat agatttacta aagaagaaaa aaagagaaat
     4681 tttgacttct atgaaaaata tactgtccat gaatcttctt tatcttctag tatttattct
     4741 attattgcct cagaaataga taacctagaa aaggcttatg aattatattc aagaacagct
     4801 aggcttgatt tagataatta caataatgat acaaatgatg gactgcacat aacttcaatg
     4861 tctggttcat ggctttccat tgtacatgga tttgcaggca tgagaacatg gaatgaaact
     4921 ctatcttttg accctaagtt gccaaaagag tggaaaaatt attctttcaa tataaattat
     4981 agagataata ttattaatgt agatgtatgt agtgatttaa ttaaaataga aaatttaaaa
     5041 ggtagaccaa taaaaattat tgtatatggg aaaaaatata tattagaaaa atgtataaaa
     5101 attgataaat agatttaata atatttttat tatataaata gttaaaataa gctatctaat
     5161 tatttattta ttttaactat tttgtgtgat agaaaactat atattataac aatagtagtg
     5221 cttttaatta aatatatttc ataaatcttc ataaaatctt caaaatttcg taaagaatat
     5281 gtcacaaaag taaggtatat tatattcagc agatagtata agggaggaca atatttatga
     5341 agaataaaaa attcattgtt ataatactga taatatcaat tttaataggt gtattagtga
     5401 aggaatattc atctagagag ataaaaaagg atgatataaa tgtcagtaag tatataaaat
     5461 atgctgattt agcaagtaaa aataatgcac aagttaactg gaagtatgta gcttccattg
     5521 ttgctgtgtt aaataaaaat aacttaaaaa acgttaagga ttcacagata caagaagtat
     5581 cagatttatt tgttaagaat ttttctaaaa ataataaaat aaataagtta agtgatattt
     5641 tggatgagtt agaatttagt aatagacaaa aaagattggt tgataattat atagacaatc
     5701 ttaaggatta tggtataaaa ccagaaagat tgaagtctga tacaaaatat atgaagttta
     5761 ttgatgaaat taaaacagaa gcaatacaaa attataagga ttataaaata cttccatcta
     5821 taactattgc acaagctata atagaatcta gctggggtaa gtcaactttg gcaaaacaat
     5881 ataacaatct atttggtata aaggctgacg cttattggaa aggtaagtca gtgactttag
     5941 aaacgaaaga acatttagat acaattatag atgataaatt tagaatatat gatgataaaa
     6001 atgaatctat aaaagaccat gcaaaatttt tagccacaaa taaaaggtat aaaaacaatg
     6061 gtgtatttga tgcaaaaacg tatatatatc aagctaaagc attagaaaag gcaggttata
     6121 gtactgcgaa ggatgaaaat ggcaatagta tatatgcagc tcgtctaata gaattaattc
     6181 aacagtataa tcttcaatta atagacagtg aaattcaaag tgaaatgtaa ctttgattaa
     6241 atttttattg ataaggctat gatttttaaa atcatagcct tattttgaca tgtttttact
     6301 tgtaattatt aaatcgatat cattatcttt caaaatttac tttatactgt aaatcaaatt
     6361 atttaagtta aaacttggaa ttatttataa aaggattatt tactttatct aaattctgca
     6421 cttaaagaac atcttttccc ttaagactga ccgttagtct ataaaaatta taattactta
     6481 taaaaaagtg aatagagaga tatatatata attttcagaa agacttttac ttgtaaattg
     6541 aaattaatga agtaaaaaag gattctttct taaaagtaaa taacaactag atagtgaata
     6601 ataaaaaatg gtaatttgaa ataattttta tgaatagtat taatatatag atacagggag
     6661 attgatgcga ttatgtatga aaataataag gtaatataca accttgaaag atgtgaaaaa
     6721 ctagaaaaga ctctttattt atctcaattt aatacatata aaaattttaa attagcttct
     6781 aaaaaaactg taataaattc attagagaca tatgtttaca atatgaatat taacaatata
     6841 agtcttgttg atactataga atgtatatca ttagaagatg aacaacttac aggaaagaag
     6901 ttgattttag ttggtgatat agatattgat gcaatattag attatgcagg aaataaaaga
     6961 aatagaaatt ctagtaaaaa aaatacattt aaattaaaaa taccctttag tacatttata
     7021 caaatgccta gaaagataga aaataaagat aaaattaatt taaagtatct tatacaagat
     7081 attacttcat ctattttaga tgataattta tttattagtg ttactgcaat tataagttat
     7141 gaaaatagtt ccaagataga gtaatcttta aattatagaa aggtggatgc aatgagaata
     7201 acgaaaacta cttttaatga tgtattttca aatgatgcaa atggaagtat tataaaagta
     7261 gaaaaatatg ttgataaaaa atgtgcatct gtatttgaga ttttgaccta cactattatt
     7321 gttacaaata caagtaggta caaaactgga aatatatttt tcaaagatta tatttctaaa
     7381 tatatagagt ttataaataa tactgtaaaa gttaatggca ttataaaacg tggattagac
     7441 ccacagaaag gtttttacat agggagaata gatgcaagtt gtaaaaaaat aatatctttt
     7501 aagagtgtag ttttaccaaa ttctgcacat aggattataa agaatagtgc taatatatac
     7561 tattattata agtgtaatct agataaattc ccaacaagaa tatcaataga aagtaataga
     7621 gtttatacta atgtaaataa aattgtattc aaacaattga atataagtaa tactttaaaa
     7681 gctcctaaaa atctaagaga tatattaaaa gtaaatgtaa atagtaaaat atttgatgtt
     7741 aaacctatga aaaatcttat aaacaaaggt agtaatttga aattatgtaa cttgatagtt
     7801 tttgggtgta tagaagttga aatagactat agttgtaaaa ataggagtaa ttttaaaaca
     7861 gtaaataagt ctaatgacat taaaaaagat aagtattata aaaatgatat acaaaataac
     7921 aatgaaaata taaacgattg taaaaagcaa ataagttttg gtgataataa ggtaaaaaaa
     7981 ataacaaaaa cttttggatt ttcttgtttc atttgttctc cagttggaat tatttatgaa
     8041 gatatgaaaa atataaatat aaaaattgaa catacatcaa taaatgaatt aaatccagaa
     8101 gaattatttg taaatacatc acttttattg tattattaag tattttaaag ctaaaactta
     8161 aacttattaa aatagcatt
//
LOCUS       DAEQAF010000132         7983 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.136, whole genome shotgun sequence.
ACCESSION   DAEQAF010000132 DAEQAF010000000
VERSION     DAEQAF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7983
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.136"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            22..98
                     /locus_tag="KRN00_003333"
     tRNA            22..98
                     /locus_tag="KRN00_003333"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56..58,aa:Asp,seq:gtc)
     gene            108..182
                     /locus_tag="KRN00_003334"
     tRNA            108..182
                     /locus_tag="KRN00_003334"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:140..142,aa:Thr,seq:tgt)
     gene            197..281
                     /locus_tag="KRN00_003335"
     tRNA            197..281
                     /locus_tag="KRN00_003335"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:231..233,aa:Tyr,seq:gta)
     gene            291..374
                     /locus_tag="KRN00_003336"
     tRNA            291..374
                     /locus_tag="KRN00_003336"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:325..327,aa:Leu,seq:tag)
     gene            398..472
                     /locus_tag="KRN00_003337"
     tRNA            398..472
                     /locus_tag="KRN00_003337"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:430..432,aa:Gly,seq:gcc)
     gene            497..573
                     /locus_tag="KRN00_003338"
     tRNA            497..573
                     /locus_tag="KRN00_003338"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:531..533,aa:Arg,seq:tct)
     gene            583..658
                     /locus_tag="KRN00_003339"
     tRNA            583..658
                     /locus_tag="KRN00_003339"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:616..618,aa:Gln,seq:ttg)
     gene            667..742
                     /locus_tag="KRN00_003340"
     tRNA            667..742
                     /locus_tag="KRN00_003340"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:700..702,aa:Lys,seq:ttt)
     gene            745..833
                     /locus_tag="KRN00_003341"
     tRNA            745..833
                     /locus_tag="KRN00_003341"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Ser,seq:tga)
     gene            837..912
                     /locus_tag="KRN00_003342"
     tRNA            837..912
                     /locus_tag="KRN00_003342"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Phe,seq:gaa)
     gene            919..992
                     /locus_tag="KRN00_003343"
     tRNA            919..992
                     /locus_tag="KRN00_003343"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:953..955,aa:Met,seq:cat)
     gene            1007..1083
                     /locus_tag="KRN00_003344"
     tRNA            1007..1083
                     /locus_tag="KRN00_003344"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1041..1043,aa:Ile,seq:cat)
     gene            1101..1177
                     /locus_tag="KRN00_003345"
     tRNA            1101..1177
                     /locus_tag="KRN00_003345"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:His,seq:gtg)
     gene            1186..1261
                     /locus_tag="KRN00_003346"
     tRNA            1186..1261
                     /locus_tag="KRN00_003346"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1219..1221,aa:Lys,seq:ttt)
     gene            1269..1342
                     /locus_tag="KRN00_003347"
     tRNA            1269..1342
                     /locus_tag="KRN00_003347"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Cys,seq:gca)
     gene            1350..1426
                     /locus_tag="KRN00_003348"
     tRNA            1350..1426
                     /locus_tag="KRN00_003348"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Arg,seq:acg)
     gene            1439..1514
                     /locus_tag="KRN00_003349"
     tRNA            1439..1514
                     /locus_tag="KRN00_003349"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1472..1474,aa:Val,seq:tac)
     gene            1590..2003
                     /locus_tag="KRN00_003350"
     CDS             1590..2003
                     /locus_tag="KRN00_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829176.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVDGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2312..5743
                     /locus_tag="KRN00_003351"
     CDS             2312..5743
                     /locus_tag="KRN00_003351"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBH1829177.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTRESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5985..7913
                     /locus_tag="KRN00_003352"
     CDS             5985..7913
                     /locus_tag="KRN00_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBH1829178.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
BASE COUNT         3106 a         1030 c         1617 g         2230 t
ORIGIN      
        1 cctgttggtc ccaccatttg cggcctggta gttcagttgg ttagaatgcc agcctgtcac
       61 gctggaggtc gagggttcga gccccttcca ggtcgccaaa ataaaatgct ggtgtggctc
      121 aacggtagag cagctgactt gtaatcagca ggttgtaggt tcgattccta tcaccagctc
      181 catataaaat taatacggag gatttcccga gcggccaaag ggggcagact gtaaatctgt
      241 tgtcatcgac ttcggtggtt cgaatccacc atcctccacc aaaaaaatgc gcggatgtgg
      301 cggaattggc agacgcacta gacttaggat ctagcgccat tggcgtgggg gttcgactcc
      361 cttcatccgc accattttta tttaatttaa taaacgagcg ggaatagttc agtggtagag
      421 cgcaaccttg ccaaggttga agtcgcgagt tcgaatctcg tttcccgctc caaattttat
      481 gtttatgttg taatgtgggt gcatagctca gctggataga gcaacgccct tctaaggcgt
      541 gtgtccgggg ttcgaatccc tgtgcgctca ccacatatat attggggatt agccaagtcg
      601 gtaaggcaca tgactttgac tcatgtatgc gtaggttcga gtcctgcatc cccagccaaa
      661 cagtatggtc tattagctca gttggtagag cacctgactt ttaatcaggg tgtcccgcgt
      721 tcgagtcgcg gatagatcac caatggagag gtgtccgagt ggtttaagga gctggtcttg
      781 aaaaccagtg acttcgaaag gggccgtggg ttcgaatccc accctctccg ccaaatgccc
      841 agatagctca gtcggtagag caggggactg aaaatccccg tgtcggtggt tcgattccgc
      901 ctctgggcac caaaatgtgg cggtatagct tagttggcta gagcgttcgg ttcatacccg
      961 aaaggtcata ggttcgactc ctattaccgc tactaaaatt taatgtgggc cattagctca
     1021 gttggttaga gcgcccggct cataaccggt aggtctgggg ttcgagtccc tgatggccca
     1081 ccacattaaa ttaacttatg gtgggtatag ctcagttggt tagagcgcca gattgtggct
     1141 ctggaggtcg tgagttcgac tctcattatc caccccaact tatatggtct attagctcag
     1201 tcggtagagc acctgacttt taatcagggt gtcccgcgtt cgagtcgcgg atagatcacc
     1261 aaaaaggcgg cgacatagcc aagtggtaag gcagtggact gcaactcctt gatccccagt
     1321 tcgaatctgg gtgtcgcctc caataaaatg cgctcatagc tcaactggat agagtgtctg
     1381 actacgaatc agaaggttag gggttcgagt ccctttgggc gcaccatatg aatagcgagg
     1441 gattatagct cagctgggag agcacctgcc ttacaagcag ggggtcacag gttcgagccc
     1501 tgttaatccc accagtgcaa acctctagta aaactactag aggttttatt tttgattgaa
     1561 aaagttttta tatttaggag gtaaaaaatt tgtatatagt aataggaaat gaaatagttg
     1621 atagtgaaga acttaaaata attatagata aaaatagtga atttaaagtt gaaaaagatt
     1681 taagtaaaag cacaaaaaga gaagatgtaa tagcatatca gttaagtata gatttaaatt
     1741 acctagattc tcttataaat gagcaatgta atttagccag tctatctgat gaagagaaat
     1801 ttgatgaata tatgactttg tctgatgaac ttgcactgga tttagaagag ttaatgccaa
     1861 aatatacaat aataaatgct agagcatata aattagacga ggtagatgga attgtaaaaa
     1921 taatactagc tgtagcgtat gcagatttag ggcacttaaa actttctgat gtagtaaaga
     1981 ggctatctag acaagtagat taggatatga atatgaacta tattaaaaaa atgtataaaa
     2041 tcttacgtaa agatgaaaat aattatgtaa acatagaaaa aaacagtata aaatcaagtc
     2101 aattgtagaa attttcacat aaattcatct gaaattctgt aaaaaatgcc ttaattttaa
     2161 tgaggtaaat cgagtttaca cagtctaaaa attacttata tttataaatt tatcttatta
     2221 attaaggaac tttcttaaac atcttcaaaa ataaagtatt ttagtctata atctttaata
     2281 ttacacaaac aataaaggag aagaatagag tatgcttaaa aagtttaata aaatactagt
     2341 ggctaataga ggcgaaatag ctataagaat atttagagcc tgttcagaat tggggataaa
     2401 aagtgttggt atatacagta aggaagataa gtatggattg tttagaacaa aagcggatga
     2461 atcatatttg ataggagaag gtaaagggcc aatagatgca tatttagata tggatggaat
     2521 aatagaccta gcaaagagaa aaaaagttga tgctatacat ccaggatatg gttttctagc
     2581 ggagaatgca gaatttgctc gtaaatgtga agagaatgga attactttta taggaccatc
     2641 atctaaggta atgaatatga tgggggataa gattaactct aaaaaaatcg caaaagaagt
     2701 taatgttcaa actataccag gagtagaaaa agcaataaga agtactgaag aagcaaagga
     2761 agttgcaaac aaaataggat atcctgttat gataaaagca tctaatggcg gtggcggtag
     2821 aggtatgaga attgtacatc gcgaagaaga cttagagctt gaatatgaaa ctgcttgtag
     2881 tgaatcaaga aaagcttttg gagaagatat tatatttata gaaaaatata tagctgatcc
     2941 aaaacatata gaagttcaaa tattaggtga taattatgga aatatagttc acttatatga
     3001 aagagattgt tcagttcaaa gaagacatca aaaaataata gaatatgcac cagctttttc
     3061 gttagatgat aaagtaagaa aagagatatg tgaagatgca gttaagttat caaaacatgt
     3121 gggttattct aatgcgggaa cattagaatt tttagtagat gcaaatggtg ggcattattt
     3181 tatagagatg aacacaagag tacaggttga acatactgta acagagatgg ttacaggaat
     3241 agatatagtt caaagtcaaa tactaatagc ccaaggttac agcttagata gtgaagaaat
     3301 taatataaaa tcacaagatg atgtggaaat aagaggttac tctatccaat gtagaataac
     3361 tacagaagac cctaagaata aattcatgcc tgatacaggt aaaattcaag tttatagaac
     3421 tggttcagga tttggtataa gactagatgg aggaaatgga tttacagggg caaacataag
     3481 tcctcactat gatagtttat tggttaaaac aatatcttgg gatagaacat tccaaggagc
     3541 aataaataaa actataagat ctataaaaga acttagagtt agaggtgtta aaactaatgt
     3601 aggattccta gttaatgttt taaataatcc tatattctca aatggtaaat gtagtactaa
     3661 gtttatagat gaaaatccag atttatttga aataacagaa agtaaagaca gaggaacaaa
     3721 attacttcaa tttataggag atgtaattgt aaatgataat gcttgtaaag aaaaaccatt
     3781 atttgatgca ttacatgacc caagaatgga taaggatggt tcaaaatcgg aaggaagtaa
     3841 aatacttttc gataagttag gtaaatctgc atatatagaa aagataaaaa atgataagaa
     3901 attactatta acagatacaa caatgagaga tgcacatcaa tcattattag caacaagaat
     3961 aagaacatat gacttattaa aagctgctaa gccaacagaa aaatatcaaa aggatttatt
     4021 ctcacttgaa atgtggggag gagctactta tgatgttgca tatagatttt taaaagaatc
     4081 tccttggcgt agattacaaa agctaagaga agaaatacca agcataatgt tccaaatgtt
     4141 gcttagagca tcaaatggag ttggatataa aaactatcca gataatgtaa tagaagaatt
     4201 tacaagagaa tctgctagac aaggtataga tgtatttaga atatttgatt cattaaactg
     4261 ggttgaaaat atgaaaccat ctattaatac agctttagaa actggaaaaa ttgttgaagc
     4321 aactatgtgt tatacaggtg atatactaga taagactaaa actaaataca atctagaata
     4381 ttatattaaa atggcacaag aattagaaag cttgggagca gatataatag caataaaaga
     4441 tatgtcaggt cttcttaaac catattcagc ttacacatta gttaaagagt taaagaaaaa
     4501 tgtaaaagca ccaatacatt tacacactca tgatacaagt ggaaatggtg tagcaacttg
     4561 tttaatggcg tcagaagctg gagtagacat aattgatgct gcattagaat ctatggcagg
     4621 acttacaagt cagccatcac ttaatgctat agtagaggca cttaagaata cagagagaga
     4681 tacaggaata gatttatttg gatatgatga gttaggaaaa tattataagg atttaagaaa
     4741 agtttataat aaatttgaaa gtgatttaac taattcttgt gcagaaatat ataattttga
     4801 aataccagga ggccaatata caaacttaaa acctcaagct gatagtttag gattagttaa
     4861 tagatttgat gaagttaaag aaaaatataa agaagctaat gaagttgtag gagatataat
     4921 aaaagtaact ccatcttcaa aagttgtagg agacttagct atctttatga ctaaaaataa
     4981 attagataaa gataatataa tagaagaagg taaaaattta tcattcccag attctgttgt
     5041 ggattactgt aaaggtatga ttggtcaacc agaaggtgga ataccaaaag atttacaaga
     5101 ggtagttcta aaaggtgaag aagctataac agtaagacca ggttcattat taccagcaga
     5161 agattttgat gaaatagcta aatatctaaa tgaaaagtat gatataaatg ctaatataag
     5221 aaatgttata agttatgctt tatatccaaa agtatatgaa gattatatca aacatctaca
     5281 acattataat gatatatcta aacttgaaag tgatgtattc ttctatggat taaataaaaa
     5341 tgaagaatgt gaagtagaaa tagaagaagg taaggtatta acaataagat tagttgaaat
     5401 tggtgaagtt aaggaaaatg gatttagaac tataggattt gagttaaatg gaatggttag
     5461 agaagtagaa ataaaagata agaatttctc tggaaaaatt aataatgttg aaaaagctga
     5521 tatgaatgac cctcttcaaa ttggagcaag cataccagga aaagttataa aaataatggt
     5581 taaagaagaa gatgaagtaa aagcaaatca accattaatc gttatagagg ctatgaagat
     5641 ggaaactata atagttgcta agactgatgg agtaattaag tcaatcaaag taaaagaaga
     5701 tgatatggtt gaagataaac aattattaat gataatgaag taatttaatt aaaataaatt
     5761 aaaaagcact ctgaaatgtt taataaaaaa tgttttagag tgtttttatt tattttaatt
     5821 aaatatttgt taaaaaaaag aggacaatta cctccagatg tagaaataaa gctagtaagg
     5881 aaaatgttat ctaaaaattc taaatatagt aaatattttc cataatattt cttaggaaat
     5941 aacagcaaag ataaaataca taaatttaaa aggtgggtgc ttatatgaag gtttatgata
     6001 gtaaaatgtt gagaaatgta gcggtattag gacatagcgg atgtggaaaa acaaatctaa
     6061 tcgaaactat agcttacaca gcaaacacta ataagatacc taaattaaca gacaaggtaa
     6121 atatgactta tagcatggga ttaataccta tagagtataa tgattataag tttaacttat
     6181 tggatacccc aggatatttt gactttagcg gagacgttgt gtcatctctt agagcaagtg
     6241 atgcagcaat aatagtaata gatgcaacag cgcctattca agttggtaca gagaaatcat
     6301 tagaactaac tgagagtatt cctaagataa tgtttataaa taaaatagat aatgaaaagg
     6361 caagatacaa agatgcaata gcaatgttaa gagaaaaata caataataag atagttccta
     6421 tgataagtcc tatatacaaa gataaaaact ttgtaaagtt acataatgtt tttgaaaaca
     6481 tagatgattt agaaggtgaa tttaaggaac aagctatgag tgttaaagaa gcattaatgg
     6541 aacttatagc agaaactgat gaccaaatat tagataaata ttttaatgga gaagaactaa
     6601 ctacagaaga gatacaaaaa ggtattatta taggtataca aagaggtgat attatacctg
     6661 taatatgtgg ttcaactata aataatatag gcacaaagga aatattagat acaatatcga
     6721 gttatttaga acctatcttt acagaggaaa gcaaaccatt taggggatta gtatttaaaa
     6781 ctatggttga cccatttgtt ggaaagatgt catatataaa aattactgag ggtgtacttt
     6841 ctaaggataa agatgttttt aatataaata aaaatgtaaa agaaaaaata gctaatatat
     6901 atacattgag aaatagtgaa ttagtagaaa tagaaaaagc taaagctggt gatatagtag
     6961 ttataactaa agttaattct ctaaaaacag gagacactat atctgcagat aaagatgcag
     7021 aagctttaga aaagatagat tttcctaaac cacaaatata ttatgcagta actcctaaga
     7081 ataaaggtga tgaagaaaaa gtagcatctg tattaaataa actagtagaa gaggacccta
     7141 cattacattg gtatagaaat acagagacaa aacaagcact tttaggaggt caaggagaac
     7201 ttcatataaa aacaattaaa aataaaatga aagataagtt tggtgttgat gttgaattga
     7261 atgaccttaa agttccttat agagaaacta taaaaggaac agctgatgta caaggaaaac
     7321 ataaaaagca atcaggtggt catggtcaat atggagacgt aaaaataaga tttgaaagat
     7381 gtgaatctga ttttgaattt acagaagaaa tatttggtgg ttctgtacca aaacaatata
     7441 taccagcagt tgaaaaaggt ttaaaagact ctatgcaaaa aggtatatta gcaggatatc
     7501 ctgttacaaa cataaaagct acgctttatg atggttcata ccatgatgta gactcttctg
     7561 aaatggcctt taagatggca gcaagtgcag cctttaaaaa aggtatggaa gaagcacacc
     7621 caatactact agaacctata atgaaactta agataactgt tccagaagaa tatatgggag
     7681 atgtcatggg tgatataaat aagagaagag gaaaaatatt tggaatggaa ccagatgaca
     7741 aagggaaaca aataatattt gcagaagctc cacaagcaga gacatttaaa tatgcaatag
     7801 atttaagagc aatgacacaa ggtagaggat actttgaaat ggaattagag agatatggag
     7861 aggttccatc acagtttgca gaaaaaataa ttgggttagc tactgcaaag taatgaacaa
     7921 aataaataga aaaataatta atatatatta ttaaaaatat ttttagggtt ttaactaggt
     7981 ata
//
LOCUS       DAEQAF010000133         7750 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.137, whole genome shotgun sequence.
ACCESSION   DAEQAF010000133 DAEQAF010000000
VERSION     DAEQAF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7750
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.137"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(234..2513)
                     /locus_tag="KRN00_003353"
     CDS             complement(234..2513)
                     /locus_tag="KRN00_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBH1829179.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(2780..4234)
                     /locus_tag="KRN00_003354"
     CDS             complement(2780..4234)
                     /locus_tag="KRN00_003354"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBH1829180.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            4398..5267
                     /locus_tag="KRN00_003355"
     CDS             4398..5267
                     /locus_tag="KRN00_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1829181.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNMHDIESIKSFIEQINISESNTEFGNEILRNALFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(5480..7552)
                     /locus_tag="KRN00_003356"
     CDS             complement(5480..7552)
                     /locus_tag="KRN00_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1829182.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALASFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENALVEKIDSLTNGEILDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVSTAKEENRVSIL
                     RDDIEKIG"
BASE COUNT         2627 a         1299 c          825 g         2999 t
ORIGIN      
        1 attactatta ttactatcta aagtattttg ctataatccc atatactctt acctcaaaaa
       61 cattcaaatg taaaaaatac tacatattaa taaactttgc ccaataattc ctaaaataat
      121 atcctaacaa tgatttatgt ttttataata gtatattttt acataaaaaa gtgaacattg
      181 attaacaaag ttcacttttt tataaatttt tatgttataa ttcacaattt tatttaattt
      241 gtttcttttc tatttaaact atatctatct aatattaatt tttcatattc ttctattggc
      301 attggtctag caaataaaaa tccttgagcc atatcacaac ctataaacct taaaaactct
      361 gcttgctcta cagtttcaac accttctgaa acaactttta tatcaagttg ctttgccatt
      421 tgaacaatac ttgaaactac aatttgactc ttttttgcat ttcccactgt tataaagaat
      481 tgcctatcta atttcaatac atcaattggc atatctttaa gcatatttaa agaagaataa
      541 ccagaaccaa aatcatccat agaaatttta aatccaacag atttcaaagt ttgcattatt
      601 ttaaataata tttttgtatt gtcaaatatt gcactttctg tcaattcaat ctcaattaaa
      661 tttggttcaa tttcatattc ttttgttatt ctttcaagct cagaaataaa gcctggattc
      721 tcaagatgta ctcttgataa gtttattgat ataggaaatg tggggaaatt ttcattttcc
      781 caacgtttaa aatttttaca aacttgggta aatacaaaca tatccaattc tgttataaag
      841 ccatttttct caaaaatagg aataaataca cctggactta ttagaccttt tttaggatgt
      901 tgccaacgta caagtgcttc agcacctaca attttagtag ttgataaatc aaccttaggc
      961 tgtaaataaa ctttaaattg ttcatttttt aaagcatcat gcatttcttg ttcaatatca
     1021 cgttcttcta tgagagtttc ttttaaattt tcagcataaa tctcataaac ttttaaatat
     1081 tttcttttta ctgtagtttt tgcaatcata gctttgtcaa gacaggtaga aatatttgtt
     1141 tctccctctt caacaaaata tacacctatg gatggaatta aattgagttc tactcccaaa
     1201 cttgttttta tcattgacaa ttttttacgt ataagttcac atatttctat aattgactct
     1261 ctattatttt tcttttcaaa tattatagca aaattgtcat ttgaaattct tgaaaataca
     1321 gattgctctt taaatatatt cttaattatc tctgctattt cctttaatac tctatctcct
     1381 tcttcatacc caaacctatc atttactagc ttaaacttat ctatatcaaa ataaattaaa
     1441 actagattct ttttctcatg agaggataaa aattttcccc cttcaagatt aaatttattt
     1501 gaattgccaa tacctgtaac gttatcttta aaagcaaatt cttccaattt ttccttactc
     1561 tttttatgta taaatagtat ataaattgtt aatgccgtaa agattataat caagactaca
     1621 catgctgata atgtaagttt tataatagca tatgatttct cagatatagc agttttagga
     1681 acttcagaaa aaagatacca atcattgatt cctattgggg cataacttaa ataatatcct
     1741 tttccaaaca tactataact taatgaacct gatttaaagt tttttatatt tgacttcata
     1801 ttgttgatac tagattttga tattgaatca cttctgccaa tgtaagaaaa taaattttct
     1861 ttagtagagt tggcgttttt actgcttgga tttaaaacaa tatcaccatt acttctagtt
     1921 atataagaat atccttttcc attaaatgta ggtacagaaa gtattttttc atacaacttc
     1981 gtactatgtg tggcaaatat aactccttta acctcattat ctttataaat tggtacagaa
     2041 tatacattaa tattactatt ggtattttta tcatcttcta ttacatcttt taatttgcct
     2101 gttataacca cttctccttg cattgatttt aagaaataat ctcttttaga aaagtcttct
     2161 atataaccat ctgtagtgta tgctgtacca tttggtaaaa taactcccat tcttttaaat
     2221 gaactattaa tagcttgcct ttttagtata gaaaggatat tatctacttc aaaagactct
     2281 tctccttcaa taaatattga aattgactct agtaacttta tatctccatt aatttgtttt
     2341 tttaacacat tgacgctttg atttgctatt tctgaaagat attgattcgt ttcttcacct
     2401 aatgtcttat tcaaccttga accataaatc aaacaggaaa ttgtaattac taagatactt
     2461 atgacagcaa ttatggacaa accataccta ttattttttg catcacttaa cattatgctt
     2521 cctgcctttc tcgaatctat gtataatcat tatcttatga caattattgt aaacatttta
     2581 taataatact tatttttcca tatttactgt aattatacaa aattataaac tttattacaa
     2641 caataaatta attaatatag atattagtgt ttacattatt gcattatcta ttttacaatt
     2701 atttacatat aaaaaaatgt aatatcaaag tgaagcttga tattacattt ttgttcttgt
     2761 attttgttta atttttatgc tacatcttac ttaaacactc atttgcaact tctttatcat
     2821 caaaatgatg cttaacttta cctataattt gataagtttc atgtccctta cctgttataa
     2881 ttacaacatc atcctttttt gccatactta tagcttctgc tatagcttgt tctctatcaa
     2941 caacaacatg gtaattttct tttttcttgt caattccttc aagtatatct tttattattg
     3001 cctctggttc ttcagttctt ggattatcag aagttataat acataaatca gaatattttt
     3061 gtccaattgc tcccatcaaa ggtctctttt cagtatctct atctccacca cacccaaaca
     3121 cagaaattat ttttccttct gcaaattgtt gagttgtctt tagtacattt tcaagtgcgt
     3181 caggagtatg agcatagtct acaattacgc ttataccttt atcatttgga actgtttcaa
     3241 accttcctga tactccatta gaaagtctaa ggccttcttt atatattggt ttaggtatgc
     3301 caagtacata gcaagcagct ataactgcta aagtattata tactgtaaac attcctggaa
     3361 ctggtataaa tattacttct tcatatgaag gtgttattaa tctataagat actccatccg
     3421 aatctgattt tatatctcta gccataaaat cagccttagt atcaacacca taagtgtaac
     3481 aaggtacatt tatacctttt atattttcat atatcttctt tccaccttca tcatctatgt
     3541 ttattatatt tgccatagta gtcttaaaaa ataatttttc ttttgctttt ctataatcct
     3601 ctaaatcttt atgaaaatct aaatggtctg gtgttaaatt tgtaaatatg cctagtttaa
     3661 agtctgtttc atcaactcta tttaatgcca atgaatgtga tgaaacttcc attgcacagt
     3721 agtcacatcc attatccaac atattattaa aatgatattg taaatctata ctttctggag
     3781 ttgttgaatt ggaaacaatg tctttttctc catcaaaaat ttttatagtt cctataagtc
     3841 caactttatt cttatttaaa gttaatatct catttagtat agtagttata ctagtttttc
     3901 cattagtacc tgtaactcct ataacgttaa atttttgaga tggatgattg taaaaattat
     3961 cagctacttt tgccatatct tttcttgtat cttttacctt tataaatgta catcctttta
     4021 ttgctacatc ttcttcaaca agaaatgcac ttgctccctt ttctatggca tcttttatat
     4081 acttatgacc atctgacaca aatcctttta tacatataaa taatgtacct tttgtaacct
     4141 ttcttgaatc atattgtaca ttattaatat ctatatttaa ttcacccttg acattgatta
     4201 tatccaaccc ctgtataata tcatttaatt tcataaatgc tttcctccct ttaaactctt
     4261 tctgctaaaa ttacactaca tataatatta tattaagaat tttttactat gtgaatggtt
     4321 aaaaatgctt gaaacattgc aaaaaatgct ctataatttt ctataatata actgaggaaa
     4381 ggtcttctat aaaaactatg gataataaaa tcgggtactt aaacgataac tttaaaatat
     4441 ttaatattag agataaaaaa gatatacaat ttgaatacca taatcatgat tttaataaga
     4501 taattatatt tataaatgga aatgtaactt attttgttga tggtattccc tataaactaa
     4561 agccttggga tatactcttt atcagcaata atgaaatcca taaaccagtt atagattcaa
     4621 atgtctttta tgagagaatt gcaatatgga ttagcccaga atttatgaaa aaaaatagtg
     4681 atgctagtag tgacttagaa aaatgtttta aaatagctac agagaataaa tgcaatagat
     4741 tgcgtttaaa tatgcatgat attgaatcta ttaagagttt tattgagcaa ataaatattt
     4801 ccgaatccaa tactgaattt ggaaatgaaa tattgagaaa tgcattattt atacaactta
     4861 tgatattctt aaacagaatt ttcctaaaaa atgaaaatat ggaatcaaca gaagatgttt
     4921 tttatgatga aactattaag aaagtattaa actatataaa ttcaaatata gatgataagc
     4981 tttcaataga tagcatatcg tctgaatttt ttataagtaa gtattatctt atgagaaaat
     5041 ttaaatctca tactggaacg tctatacaca attatatagt tcaaaaaaga ttaattttgg
     5101 caaagtcact aataaccaat ggtcacctta tgagtgaagt ttgtaataaa tgtggattca
     5161 acgattattc tagttttgta agggcattta aaaaaaacta cggggtatct cctaaaaatt
     5221 atataaacaa taaaaatcct ttggatatta ctcttttaga tgaatagata atttatgtaa
     5281 attttatttt aataaaactt gaagtattag tgtatttatc ttactaatac ctcaagtttt
     5341 ttaatgtttt aaaatatatc aaaatataat gatatatatt tctattactt aaaatatata
     5401 ttaaataaat tgcatgttaa ctgaacctat ttatatattt attaaatccc acataacttt
     5461 tagttacact atcatatagc tatcctattt tttcaatatc atctcttaat atacttactc
     5521 tattctcctc ttttgctgtg cttactcctt ttttaatgct taatttctga ttttgttcta
     5581 aattcgtaaa tactacagga cttattgttg atagaccatt tttttcaata tattctaagt
     5641 ccattttaac taatttttct cccgctttta cttcatcccc tacattcaca aatacttcaa
     5701 atccatttcc ttctaaattt acagtttcta tccctaaatg tataagtatt tctactccac
     5761 ttttttggga ttttattatt attgcatgct tagttggaaa tataactcca atagttccat
     5821 caactggtga ataaatcaat ccatcactag atttaattgc aaatccatcc cccatcagtt
     5881 tacttgaaaa tacagaatct ggcacttctt ctatatctaa tatctctcca tttgttaatg
     5941 aatcaatctt ttctactaaa gcattttcca tatttgcaac ttccatattt tttttcactt
     6001 tatttttatc aacattttta gtaacagtac tttcaacctt tgtttttccc tctattatat
     6061 cttttatatc agactttatt gaatccgatt ttggtccaaa tatagcttga acattgttgc
     6121 caataaccat aacacctgct gctccaagtg atttcaattt ttctttatct actttattta
     6181 tatcatttac aaccaatcta agtcttgtta tacacgcatc taggctcttt aaattgtctt
     6241 tatttcctaa agcaatcaaa atctctgatg ctaattcatt cttagacatt tcaatgactt
     6301 cagcgttagt ttctgactca tcttctcttc ctggtgtctt taaattaaac tttcttatca
     6361 taaatctaaa tacactatag tataatactg caaaaccaat acctaccaag atagccaagt
     6421 accatggagt tctattagga agaacaccaa ataataagaa atctattaat cctcctgaaa
     6481 atgtgaatcc aattttaact cctaataatt gcataattgc gtatgataaa cctgaaaata
     6541 aacaatgtat tgcaaataat actggtgcaa caaataaaaa cgcaaactct attggctcgg
     6601 ttattcctgt taaaaaagag gctaatgctg ctgatgccat tatacctgct acaaattttt
     6661 tcttttctgg ctttgcttca tgcaccatag caagagctgc tgctggaaga ccaaacatca
     6721 taaatggaaa tgcacctgtc ataaaagtac ctgctgtgaa atttactcca tctttaagtt
     6781 gagcaaagaa tatcttttgg tcacccatta caagctcacc agctttattt acatattctc
     6841 caaattgata ccaaaatgga ttatggaaaa catgatgcaa accaaatggt attaatagtc
     6901 tttccaaaga accttccata aatgctgcta gtgtttgatt tgcttctata acattttttg
     6961 agaaactaag taatccctct tgtattggag gccaaataaa agacaatata attcctattg
     7021 ctatagcaac taatgaagta acgattggta caaatctttt acctgcaaaa aaacctagat
     7081 actgaggtaa ttcaatttta taaaactttt tataaagata agcagccact atccctataa
     7141 taataccacc aaatacccct gtttgaattg ttggtattcc aacaatattt gcatacatag
     7201 aattgtctac catatcttct gtaacacctg ccataacacc catagatgta ttgagaatta
     7261 aaaaacctac tatggctgcc aatgctgcaa caccttctcc ttcagttaaa ccaacagcta
     7321 ccccaactgc aaatataagt ggtaagttat taaatataat ttgacctgaa ctttccatta
     7381 tacttattat aagttgaaat gtaggattcg ccaaagctgg aaaatgagcc aacaatgcgt
     7441 ctcctgctaa agcattactc acgccaagta atatacctgc tgcaggaagt aatgcaactg
     7501 gtagcattag agattttcct actttttgta aaacaccaaa tacttttttc atttactttt
     7561 ctctccttat tattttatat ttttttaaat aaaaaagact taagtttata aaaagttaca
     7621 ttagtatact taattctaaa attaaactta tgttaatata aacaaaccta tattaaccta
     7681 atttcagaat taaaaataaa ctattataat ttttttataa acataagtct tgcctgcatt
     7741 atcagtaaca
//
LOCUS       DAEQAF010000134         7722 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.138, whole genome shotgun sequence.
ACCESSION   DAEQAF010000134 DAEQAF010000000
VERSION     DAEQAF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7722
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.138"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            107..2335
                     /locus_tag="KRN00_003357"
     CDS             107..2335
                     /locus_tag="KRN00_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBH1829183.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            complement(2573..2872)
                     /locus_tag="KRN00_003358"
     CDS             complement(2573..2872)
                     /locus_tag="KRN00_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBH1829184.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            3078..6119
                     /locus_tag="KRN00_003359"
     CDS             3078..6119
                     /locus_tag="KRN00_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBH1829185.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTTENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKVDDNNISNSVKEVWKKRSGKGYYLVDEKYTSQSYMFGSVKASFSLSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDIANKKIEVNLPQNSAFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            complement(6280..7554)
                     /locus_tag="KRN00_003360"
     CDS             complement(6280..7554)
                     /locus_tag="KRN00_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBH1829186.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILASKQLKSVYLDKLLSINDK"
BASE COUNT         2854 a         1075 c         1106 g         2687 t
ORIGIN      
        1 tattaaaatt aagacaaaat tttaacttta ctatttgtgt aaaaagtaat ataatttaaa
       61 attgattata aatctaactt ttttctttat caaaatattt taggaggtga gacatttgaa
      121 aaaaactaat agtttaaaag aaattttaaa ctggaataat atcaagaatt taagaccttc
      181 aaagggttta aaaaatatat tagaaatttt taaaagtgac ctaaaagata tacgtggcaa
      241 ttatgccgta cttgtaatag ttttaggtct tgctttttta ccatctctgt atgcttggtt
      301 caatataaag gcatcttggg acccttatgg aagcactgct aatatgcttg tagcagtaac
      361 aaatgaagat aaaggaaatg aaatagcagg acaaaagatt aatgtaggag accaattaat
      421 tgaacaactc aaagataaca agagtttagg ttggcagttt gtagatgaaa aaactgctct
      481 tgaaggtgtt aaaaaaggta cttattatgc atcacttaag attccaaaaa attttacaaa
      541 agatttgaca tctttaatta cagatgatgt taaaaaaggc gaaattatct atactgttaa
      601 tgaaaaaata aatgcagttg caccaaagat tacagataaa ggtgcttcta caatacaact
      661 acaggttaat cagactatag taaaaacagt tagtgaaatc gttcttggta tatcaaacgg
      721 agttggtgca ggaattgaac acagtcttcc aaaattgaca aaagttgaaa attcccttat
      781 tgaccttcaa aagagatttg accatataaa taagactgtt gatttagctt ctgatgctac
      841 ttcaaaatta tctgatacag ttaaagatat taaatctgat ttacctacaa ttaaaaagac
      901 tctgaatgat acaaaactat tatcaagtga cttaaaaaaa ttcttagagg atacaaatga
      961 taatttagac gaactttctc ctcttattaa gtctgactta aatttaatgg ttgacctttc
     1021 atcttctgct tcttctctta cattaaattt aattgatgca gtaaatagtg gcagtgaaga
     1081 tgtacctaag ttgatagata atttatcaga aaaactttct aatttgcaat ctttaaatga
     1141 tactttggtg gattttttaa ctaaattaaa ccaacttaca tcaaataata gattggatga
     1201 tgtcatagat aatcttgaag actctagcaa taaaatagat tcatctatat caacattaaa
     1261 tgatattaaa aacaaagtta tatctggaca acaaccatct ataagtgctt tgaataatgt
     1321 tttaagtcta tcaaatggta ttggaagaat taatttaaat attttaaata attttgactc
     1381 aaaaatatca aaacctataa atagtatatt tgcaaacagt ataaaagtag caaatgatat
     1441 aattactgtt ttagataagg cagaagcaaa acttccaaag gttgaagaaa tacttactac
     1501 ttctctaaaa ctttcaggaa atgcacagga aagtatatca ttgataagag aaagacttcc
     1561 tttagcaaaa ggaatgttgg atgatttgat tgatacttta agcaaaatta gtaatggtga
     1621 agatatgaaa aaattagtca gcttgcttga aagtgatata ttgacaaagt ctaatttctt
     1681 aaaagaacct gttgaggtga aaacagagaa attatatcca attgaaaatt atggttctgc
     1741 aatgacacca ttttatagtg ttctttctac atgggttggt atattactta tttcagcgct
     1801 attgtctaca tctgtacatg gaaactataa accttatgaa atttactttg gaagaggcct
     1861 tactttttta agtatagctc ttgtccaagg ttttataata ggaactggag atatattatt
     1921 gttaggagta acagcaaaac atccaatttt attgatagtt ctgcttatgt ttactagtat
     1981 ggtatttaac tttatagtgt attctttagt ttctgtattt ggaaatgtag gaaaagcaat
     2041 tgcaatagta ctattagtcg ttcagattgg ttcttctggt ggtacattcc ctatacaagt
     2101 tacacctaca ttcttccaaa gaataaaccc tataatgcca tttacctatg caataggtgc
     2161 tacaagggaa gcagttggtg gtatatatgc tccaaatcta actaaagata tactagttct
     2221 attactattt atgattctgt ctatttgttt gaatgtactt ctaaaaggac ctataaatag
     2281 agttataaaa ccatttaatg ataaattcgg cgatagtaat ttaactggtc attaaaaaat
     2341 taattctgtc tttaaatata tttttttaat aatattctaa gttcatacta aaaggtagta
     2401 gctaaaaagc tactaccttt ttccaactta aaaactaata tttactacaa aaactgtcat
     2461 agaaaaaaac gaaaaaattc gttctttcct aaatttatct tataaatatt tagatatatt
     2521 cctacttaat aagcagagct atacatagta tttaatgtat aacttacatt atttaactca
     2581 tataatcaat tattcctgaa tttaaattat ataaatgctc aaaaccttct tcagctaaca
     2641 aattacatgc agtaacactt ctatgaccac ttctgcaata aactactact ttcttatctt
     2701 tataatcgta aatttcatct atattattga ttaactcttg taaagatata tttatagcat
     2761 tttctatttt atattcctta aattcatctt tagttcttac atctaataat aaaacatcct
     2821 tttcattttt catcatttct ttaagttgct tcttatttat attcttatac attgtctaaa
     2881 attcctccat tttatttata tattacctat accctttatt ctttatacaa caacaaatat
     2941 tatttttata tttttctctg ttatataaaa agctatactt ataaaagctt tttttattga
     3001 taataatctg ttgattaaaa taattaagaa tgttatgcta attataaatt attaaaaagg
     3061 gaaagaggta atgtaatatg tttaagcaaa ggctctctaa attattatct agtacattag
     3121 tattgagtat gttatttact gctgctccaa atattacttt tgctgataat acaaaagata
     3181 attccgaaaa atatcaaagt tctgatatag aattacatga ttatagtaaa aacgcggaat
     3241 cttacacaaa aactaaagct cttgctaaag agaaaatcca aactttgcta tcaaagtatg
     3301 gtgctgtaag tgctcaatat gctttgattg ataatggcaa aattgagatt tctggtaatg
     3361 gtggagttta cagcaaacag gataacaaaa acttaaataa ggataatatg tatagtatcg
     3421 catctatcag taaaatgttt actacaacag ctgttatgaa gttggttgat gatggaaaat
     3481 taaatttaga tactcctgtt gtaaagtata tacctgaatt taaaatggct gatgatagat
     3541 acaaggaaat cactccaaga atgttattaa atcattcatc agggttgatg ggaagtagtt
     3601 ttaaaaacac tattttatta gcagacaatg attcttatgg tcatgataat ttcttaaaag
     3661 aattacaaaa acaaagatta aaagctaaac caggagcttt ttctgtttat tgtaatgatg
     3721 gatttacttt agctgaaatt ttagtagaaa gagtatctgg tatgtcattt actaattttc
     3781 ttgataaata cataaataat ccacttaact tacaaaatac aaaaactaca gaaaatagtt
     3841 ttgatagttc aaaactagca aaagcatatg taccttattg ggaagatgca gttccacaag
     3901 ataaccttaa tgctataggt gcaggtggtt tatattcaag tgcagaaaat ctatgtacat
     3961 ttgcacaaac atttatgaaa aattcaaatg gtattctttc tcctgcttca gtaaaagcta
     4021 tggaaaacaa agaatattta aatggtctat ggcctgaagg agaagattct atacttggat
     4081 atggtttagg ttgggattgt gtcaacactt atccatttaa tcagtataat ttaaaagctc
     4141 ttacaaaagg tggagactct ttattattcc acagtaatct tatagttctt ccagatgaaa
     4201 atatggcagt tgcagttctt tcttctggtg gaagtagtca acttaacgaa ataattggac
     4261 aagaaatctt actatctgca ttaaaagaaa aaggtaaaat taaagaaata aaacctgata
     4321 aaacatttag taagccacaa caagttaaaa tgcctagctc tttaaaagaa aatagtggtc
     4381 tttatgcttc ttcaaatatg ataaaagtag atgttaatga taatggtact ttaacagtat
     4441 cttctcctta tatagaaaat ggacctgaag ataaatacgt atacataggt caagatagat
     4501 ttgtatctga aaaaggtaat agttgtttaa aatttgtaaa agaaaaaaat aatatcacat
     4561 atttaaatat gagctcttat gatgatgtcc ctggattagg tcagacagca agtttatact
     4621 atgtagctca aaaagtagat gacaacaata tatcaaatag tgtcaaagaa gtgtggaaaa
     4681 aaagaagtgg caaaggttac tatctagtgg atgaaaaata tacttctcaa agctatatgt
     4741 ttggctctgt aaaagcaagt tttagtcttt ctgatgaaac tccaggttat atagttaaca
     4801 ctaaaataat ggatgagaat aactcaaatg cttttataga aatacctggt gtaataggtc
     4861 gtgatttatc cgacattaaa cttcataaag aaaatggtac agagtattta tcttttggaa
     4921 cactaacgta tgttagtgaa gattctataa ctaatttgcc agcagaaaaa tcttttactt
     4981 gtgaactaga atccaatggt tatgcaaaat ggtataagat tggtgacgat atcgcaaata
     5041 aaaaaataga agttaatctt cctcaaaatt cagcttttgc tgtttatgat gataaaggtg
     5101 ttcctgtaaa ctattcttta gttacaaaga acaatagagt tagattgcca aaaggaggcg
     5161 taattgtttt cttaggaagt ccaaatgcta gatttgaggt tacatatcaa gatgaagtaa
     5221 atgcaagtgc acttacagga actgatagat atgaaacttc tattaagata agtcaagcag
     5281 gttgggaaaa tgctgaaaat gcagttttaa taaacgattc agcaattgca gatgctttgg
     5341 ctgcaacacc atttgcatac aagaaaaacg ctcctatatt attgactgga agctctcaaa
     5401 taaatgaaaa aactttggct gaattaaaga gattaaaagt taaaaatgta tatgtagttg
     5461 gtggagaggc ttctataaat gaaaaatctt tagatactat aaaatcaaac aatatctctg
     5521 tatctagaat ttcaggaagt gatagatatc aaacttctat gaacattgct aaagaattga
     5581 acaatattag caatatatca aagatttcag tagttaatgg cgaaaaagga ttagccgatg
     5641 cagtaagcat tggagctgta tcagctcaaa atgatatgcc tataatactt actaatgaaa
     5701 atagtaatat aactgaaata aataacttgt ttaaaaacaa aaagattgat aaatcttatg
     5761 taatcggtgg agaatataca gtttctaaaa atatagaaag taaacttcaa aatccacaga
     5821 gaatatcagg tagcactaga aatgaaacta atgcaaaagt aataaaagaa ttttacaagg
     5881 attctaagat agacaattta tatgttgcta aaaatggaat gaataaacaa gatgatttaa
     5941 tagacggatt atctgttgga gttttggctg gaaaaactaa atctcctgta atgctagtag
     6001 gaaactcact agattataat caaaaagaac tatttaaaac tatgagattt aaatctgtaa
     6061 cacaaattgg tggaaatgga aatgaaaact catttaagca aataaaagaa atagcttaac
     6121 ataactaaaa aaggctgtat tcaagtaata ttaattgaat atagcctttt tttatttaag
     6181 ttataagttt tatatgtgta aaaattaaat ttaaatatta aatgataagt ttattaagat
     6241 atagataagt ctaaaacttt gcctttttta agttagtttc tatttatcat taatacttaa
     6301 caatttatct aaatatactg actttaattg tttactggct aaaatctttt tggctggttc
     6361 aagctttaat atagctgaca gtatagctcc catagctcta tgactagcca gagcattatt
     6421 atcaaaaatt aaattttgta actgcccttt ttcaattgcc ataagaactg ctctatgtac
     6481 tgaatttgct ggagttatta ttttttcatc tctctttaat aacataatgc tatttttatg
     6541 gcaatttcta acacaaactc cacaacctag acatctatcc tcatcaattt ttatatattc
     6601 tttaccatct tccttaacct tgcttatcgc atctattgga catgcagtta tacatttacc
     6661 acactttaca caattttcat ggtttatatt tggtataaaa cttgttgtct gtactggatg
     6721 aagatttcca aatcttttag ctgctaccat tgcttcacag caacatccac agcaattaca
     6781 tataaacgta acccctttcc taacattttc tccacattga actaagttat gttcatatgc
     6841 ttgatgaagt agttctttac attctatttt atccacacgt cttgcaaatt tattatttat
     6901 taaagaattt gctacattgt caaacgtcat acatatatcc ataggagcat cacaagcttt
     6961 tccaacatgt tgcattctat gtctacagta acacatactt atacctatat gagttgattc
     7021 atcaattata tgagtagccc tttcataatc taaaatacta acctcattat cattagttaa
     7081 aacttcctct tgaacgtata ctcttccaag cttcgtttct gttgaataaa ataaatcttt
     7141 gataaaatct tcttctacat tcatatattg atagtaaagc tctgccaaaa gtttttggtc
     7201 tatatcgtgt ctcgttctca tcatggcaaa ctcaaaaaaa ccagccattg gaggaggcat
     7261 tatatatttc ttccctttat tatcttctat atctagtatc agagccttac tagcaagttt
     7321 atccaatacc ctatatgctt cactttcact tacactccaa attttagctg ctgtttttac
     7381 tctgaaaggc tttattggaa gctgagcaac taacttcgcc tcttgttctg tatatagtac
     7441 atttagtatt ttgtataatg tatcagatgg tggagcacct tgtggaaact tgtttattct
     7501 ttcctctaaa cttttataca tattcttcgc agttatatga gaaatagtaa tcaccttctt
     7561 tttcttttgt tttccaataa aatcaaatat tctttcttat tatatattct cttactttat
     7621 ataataccaa ttctttctaa atagttaaat acctctagta atttattatt agatttctta
     7681 tataaataaa aaatcattta agtgatataa taatatttta ta
//
LOCUS       DAEQAF010000135         7688 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.139, whole genome shotgun sequence.
ACCESSION   DAEQAF010000135 DAEQAF010000000
VERSION     DAEQAF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7688
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.139"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            289..1482
                     /gene="nifV"
                     /locus_tag="KRN00_003361"
     CDS             289..1482
                     /gene="nifV"
                     /locus_tag="KRN00_003361"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBH1829187.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            1507..3432
                     /locus_tag="KRN00_003362"
     CDS             1507..3432
                     /locus_tag="KRN00_003362"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBH1829188.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            3454..4449
                     /locus_tag="KRN00_003363"
     CDS             3454..4449
                     /locus_tag="KRN00_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBH1829189.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            4775..5248
                     /locus_tag="KRN00_003364"
     CDS             4775..5248
                     /locus_tag="KRN00_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBH1829190.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDKFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            5282..5776
                     /locus_tag="KRN00_003365"
     CDS             5282..5776
                     /locus_tag="KRN00_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1829191.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            5873..6394
                     /locus_tag="KRN00_003366"
     CDS             5873..6394
                     /locus_tag="KRN00_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBH1829192.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYSD
                     SDLDYKKVHFNNF"
     gene            6583..6894
                     /locus_tag="KRN00_003367"
     CDS             6583..6894
                     /locus_tag="KRN00_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBH1829193.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            6922..7608
                     /locus_tag="KRN00_003368"
     CDS             6922..7608
                     /locus_tag="KRN00_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1829194.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
BASE COUNT         3076 a          763 c         1496 g         2353 t
ORIGIN      
        1 tatttttaaa ggttttttga aaataaatct atttaaaaat taaattaaaa tgcaagaaaa
       61 acataataac tttcattttt aagaagtttt cacaaaaaag aaaaaatata gtgcaataaa
      121 tgatgcaaag taatataata gattacaaga tatgaaaagc taaaaaaata aattgcaaat
      181 gaaattaaaa tgaataaaaa ataaaaaaat aatcataagt tagaggtatc aatgaaaaat
      241 aagacttaat gtttttaaaa ttaaaagtat actaaggggg gcattaatat gtgcgttata
      301 tcaaaagata gagcaaagga aataaaaata gtagatacta ctttaagaga tggagagcaa
      361 acagctgggg ttgtatttgc aaatagagaa aaaataatga ttgctgaaat gttaagtgac
      421 ctaggtgttg accaaattga agttggtata cctactatgg gtggagatga aaaaaatgta
      481 ataaagcaca tatgtagtag aaatttaaaa tcagatataa tggcttggaa tagagcagta
      541 ataaaagatg ttgaagaatc tatttcttgt ggtgttgatg cagtagctat atcaatatca
      601 gtatctgaca ttcatataga aaataaattg agaacttcta gaggctgggt tttagaaaat
      661 atggctaaaa cagttgaatt tgcaaagaaa aatggattat atgtttcagt aaatggagaa
      721 gatgcttcaa gagcagatat agacttctta actgaattta taaatgttgg aaaacaagca
      781 ggggcagata gatttagata ctgtgataca gtaggagtta tgaatccttt ttctataaag
      841 aatgcaatag aaactcttta tgaaagaact aattttgata tagaaatgca tacacataat
      901 gactttggga tggcaactgc aaatgcactt gcaggaatag cagcaggagc aaattatgtt
      961 ggtgttacag taaatggatt aggtgaaaga gcaggaaatg cagcattaga agaagtttta
     1021 atggcactta agtgtgttta taaatgtgat ttaaataata tagatactag aaaatttaga
     1081 ggaatatgtg agtatgtagc acaggcatca ggaagaatac ttcctacatg gaaaccagta
     1141 gttggggata atatgtttat acatgaatct ggtatacatg cagatggagc tttaaaagac
     1201 ccacataact atgaaccatt tgacccaagt gaagtaaatc ttgaaagaaa aatagtaata
     1261 ggtaaacatt caggaagagc tgcagttgta aataagttga gtgaatatga aatgtatatt
     1321 tctccagaaa acgctaccaa gctattaaat gctataagag ctacatctat aagattaaaa
     1381 agaagtttaa tggataaaga aattcttcaa ttatattgtg atatactagc acatgagaaa
     1441 ggcacaacag aagaagaagc agttagaggt tcatatattt aagatataat tgtttaggag
     1501 gaaaatatgg gagataatat agtttataaa ataattaaaa aacatatagt agatggagaa
     1561 gctgttgctg gaagttcaat tggtataaaa atagaccaaa ctttaacaca agattctact
     1621 ggaacaatga catatcttca actagaagct atgggaatag ataaagtaaa gactaaaaga
     1681 agtgtggcat ttgtagacca taatatgtta caacaaggat ttgaaaatgc agacgaccat
     1741 aagtatatac aaacagtggc agataaatat ggagtttatt tctctaagcc aggaaatggt
     1801 atttgtcatc aagtattttt agaaagattt tcaacaccag gagatacact tttaggttct
     1861 gatagccaca cacctactgc tggaggtgtg ggcatgatgg ctattggagc tggtggatta
     1921 gatgttgctt tagccatggc aggaggagca tactatataa aagcaccaaa agtctgtaag
     1981 gtgaatctag ttggaaaatt aaataatatg gtatcatcaa aagatataat attagaagtg
     2041 ttaagaaaac aaactgtaaa aggtggagta ggtaaagttt atgaatatgg tggagaaggt
     2101 gtcaaaagcc tatctgttcc acaaagagct acaataacaa atatgggggc tgaacttgga
     2161 gcaactactt caatcttccc aagtgatgaa aaaacactag aattttttaa gagtcaagga
     2221 agagaagacg catgggtaga gctaaaacca gatgcagatg cagtttatga tgaagagatt
     2281 actataaact tggatgaatt aaaaccatta gctgcaaaac ctcatagccc agacaatgta
     2341 gatgaagttg aaaatatagg caagattaaa atagaccaag tggcaatagg aagttgtaca
     2401 aattcttctt atgaagactt aatgaaagta gcacaaatcc tgaaaggaaa taaagtacat
     2461 aaggatgtga gtttggtaat agcaccaggt tcaagacaag ttatggagat gattgctaga
     2521 aatggggctt tggcagatat aataagtgct ggagctagaa tactagaaaa ttcttgtggt
     2581 ccatgtattg gtatgggtca atctccaggt actgactctg tgtctttaag aactttcaat
     2641 agaaatttct atggtagaag tgggactttg tcagcacaag tatatttggt aagtccagaa
     2701 gtggcagcag taagtgcaat caagggagtg cttacagacc caagagaatt tgatattaaa
     2761 tttacaaatt tagatgtaaa tgagtttttg atagatgata gcatgataat taaacctgct
     2821 gatgtaggaa gtgatgtaga agtagttaga ggacctaata taaaaccttt ccctcttaat
     2881 acagagctaa gtcagtctat aggtggaaaa gttatattaa agacagaaga taatataact
     2941 actgaccata taatgccatc aaatgctaag ttacttcctt ttagaagtaa tataccgtat
     3001 cttgcaaact attgtttcaa tactgtagat acagaatttc ctcagagagc aaaagacaat
     3061 aatggtggat ttatagttgg tggagataat tatggtcaag gttcaagtag agaacatgca
     3121 gctttagcac cattatatct aggtgttaaa ggggtaatag ttaagagctt tgcaagaatc
     3181 cacaaggcta acttgataaa tagtggtata attccaatgg agttttgtga tgagaaagat
     3241 tatgaaaata tatctctttt agataatctg gagataccaa atattttaga caatctaggt
     3301 agtggaattt tagaagttaa gaatacaact aaaggaactt cttttaaggt caaagtagaa
     3361 ttgtcagcaa aagaagttga tgtattaaaa gctggtggaa aattaaacta cactaaaaat
     3421 caagctaatt aatatgaaaa gagggaatat tgaatgtata aagtgacact tataccagga
     3481 gatggaatag gaccagaagt tgcgaaagct atgaaaaagg tagtagaagc tactggagta
     3541 gaaatagaat gggaagaagt taatgcagga gaggcagtta ttgaagagta tggtactcca
     3601 cttcctgaat atattataga tagtataaaa aagaacaaaa tagctataaa aggcccaatt
     3661 actactcctg taggtaaagg atttaggagt gtaaatgtaa ctttaagaca ggcattagat
     3721 ttgtatgtca atttaagacc tattaaaagt tttaagggga taaaatcaag atatgaagat
     3781 gttgatttag tggttgtaag agaaaataca gaagatttat atgctggaat agaacataaa
     3841 ataggtgatt atgcagctga aagtataaag ataataacaa gaagtgcaag tgaaagaatc
     3901 gttgattttg catgtaacta tgttaaagat aataagagaa aaaaagttac agctatacat
     3961 aaggcaaata taatgaaaat gtctgatgga ttgtttttag atgtgtttag agaagttgca
     4021 tcaaaacatg gtgtagaata tgatgatttg attgtagatg cagcagctat gaacttagtt
     4081 ttaaatccag aaaattatga tgtaatggta atgccaaatc tttatggaga tatactatca
     4141 gatttaggtg ctgggcttgt tggaggttta ggtataattc caagtgcaaa tattggtaaa
     4201 gattgtgcga tatttgaagc tgttcatgga agtgctccac aaatagcagg tcaaaataag
     4261 gctaatccaa cagcacttat tcaatcatca gtaatgatgc ttagatactt aggtgaatat
     4321 gaaaatgcac aaaaaataga aacagcttta gaaaaagtat ttcttgaagg aagtaaattg
     4381 actgtagatt tgggtggctc agcttctact acagagtttg cggatgaggt gtgtaagtat
     4441 attgtataga ttttatttag ggaaaaagta aaatatagat tgaaggaaag aggctttctc
     4501 aaaatagaga gaagcctttt ttattggaat gataaaatat atttgatttt atacaaaaga
     4561 gagttcctca taaacgaaaa agttaatttt gggatatcca ttttaatttt aaaattaatt
     4621 gattaatacg caaagaaaga ttaaataaat ttattatttt taattgaact ttcaaccaaa
     4681 atatggtaaa atttaaaaaa gttgaacttt caactaaaaa tgaatatatt gattatgtga
     4741 aattctataa aacagaaact atttgacttt agccatggta gtttcagtgg aggtgtgttt
     4801 gattaagact ttagatagta atatattaag agaagtaggt actttatcta gagcagtaaa
     4861 ttcaataaat gatattaagt acaaggaatt aaagttacaa aaaggacaat ttacattttt
     4921 gacaagaatc tgtgaaaatc ctggtataaa tcttgtggaa ttatcaaata tgttaaaggt
     4981 agacaaggct acaacaacca aggctataca aaaattaata aaggcaggat atgtagataa
     5041 aaagcaggat aagtttgata aaagaggata taatttaact ccaactgata aatctttgga
     5101 agtttatgag ttgataattg aagaagagaa tagaagtata gagatatgtt ttgataattt
     5161 tacagatgaa gaaaaacaag tggtaactaa gttattagaa aaaatgagca aaaacgtaga
     5221 aaatgaatgg tttaaagtaa agagatagta aataaataca ttaacttaag gagatatttt
     5281 tatgattaga aaagcgaata tgaatgattt agaaagcatt atgaaaatta taaaatctac
     5341 agtggaagaa atgaagactt ataataatac acaatgggat gaaaactatc cattagaaaa
     5401 agactttgtt tcagatatta agaaacaaga tttatatatt tatgaagtgg atggagaagt
     5461 agcagggttt atatgtctta attatgaaga gccagaagaa tatttaggct taaattggtc
     5521 atctaataaa aaagcaatgg taatacatag aatggctgta aatccaaact ttagaaagac
     5581 aggaatagca tctaagttag ttgattttgc tgaaaaatta gctgtagaaa acaatgtatc
     5641 atacttaaag agcgatacat attcaataaa ctcaaaaatg aatttattac ttacaaagtg
     5701 tggttttata aaaatcggag aaatgagttt tttaggaaag gagaaatctt tctactgtta
     5761 tgataaaata ttataaagag catttacaat acaaggggta aataatagat tttcagcatt
     5821 agtaagggca taatataacc tagtatatgc tattatgaaa gggatgattt atatgattgg
     5881 atttctaaag aaaagaagaa gtattagaaa atacaaggat gttgaagtag agaaagaaaa
     5941 attagataaa atattaaaag ctgctctttt agctccatca tcaaaggggc ttagaacatg
     6001 ggaatttata gtggtagatg ataaagaaaa gctaattaat ttatctcaat gtagaactaa
     6061 aggtggtgga tttttcttaa aaaatgcacc tttagctatt gtaattattg cagataaaga
     6121 aaaaaatgat gtttggatag aggatgcaag tatagctgct tcatacatac aacttcaagc
     6181 tcatgaacta ggtttaggtt cttgttggat acaagtaaga aatagaatgc atgatgataa
     6241 tatagaagct gataagtaca ttagagaaga attaaaagta cctagcaagt acagtgtaga
     6301 atgtataatt tctataggat atcctgatga agaaaagaaa gcatacagtg actctgattt
     6361 agactataaa aaggttcatt ttaacaactt ttagtatata atatgttgta ttaagacatt
     6421 atattttttt ctattgttaa tatatactta aaattgtaaa aatatatctg aattttacta
     6481 acttatctag gggttatgta caaggatttt aaagataaat atagaaatta atgtttataa
     6541 tcgatacata acttgagtaa caaaatttaa ggaggttaaa gtatgggtat atttaaaaca
     6601 aaaatggatg aggactggaa agtaaactac attaaagagt ttaatgaaat gagagattct
     6661 tatgagagta aacttcaaaa aaaacagttt gaggtagata gtttgaaatc agaattggat
     6721 agactaagaa gctataaaaa tagccttaag ccaaaagaaa aacaaattac tgatgatgat
     6781 ataaataata taaagagttt aagaagagat ggcttaagct ataaagaaat ttcaaatcaa
     6841 acaagttgga gcaaagcaac tgtaagtagg gtattaaatg gactttacga ttagcatata
     6901 catggggtga tttaaattgg gatgaagtat agttacaaaa aatgcataat agattctatt
     6961 ttattgatgt ttatagttca aatattaagg atgattttga attatgtact tctaagtcaa
     7021 tttgaattta ctcttgaaaa ttttaatatt ataaacttaa tttcttttac attagttggt
     7081 ttatcgttaa ttttattttt aaaagataat tctttgtata acaaggttag aaatagaaaa
     7141 atcacagaag cttttgaaga aaataaaaac aatatactta ttgaaaagtg taagctgata
     7201 ctttttgttg tggttttatc tttagcaata attgtaactt attgtactaa gggatatgta
     7261 ctttttaatg taactatgat gactttgtct gtattgatag tcccaatatt tgaagagtta
     7321 ttttttagag aatatatatg gaactatcta agtaatttta taaagtcaaa gagtaaaatt
     7381 atctgtataa catctatact atctggaatt tataatatag gatacataga tgttataaga
     7441 aattatgtaa tattgtataa caattcaagc tacacctttg aagttattat ttcaaaaatt
     7501 atgataggta ctgtttttgg tattgtactt ggattagtta agtataggtt tagagatgta
     7561 gggttttgta tattattgag gagcttattt gctatattta ttaggtagat agtataatcg
     7621 gtttataagg ttgttttaaa tttaatttta aatcaacctt attttatttg tgttttataa
     7681 agcactta
//
LOCUS       DAEQAF010000136         7657 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.140, whole genome shotgun sequence.
ACCESSION   DAEQAF010000136 DAEQAF010000000
VERSION     DAEQAF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7657
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.140"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            159..1562
                     /locus_tag="KRN00_003369"
     CDS             159..1562
                     /locus_tag="KRN00_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBH1829195.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     misc_binding    1653..1893
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1936..2634
                     /locus_tag="KRN00_003370"
     CDS             1936..2634
                     /locus_tag="KRN00_003370"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBH1829196.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELVNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     gene            2657..3658
                     /gene="trpS"
                     /locus_tag="KRN00_003371"
     CDS             2657..3658
                     /gene="trpS"
                     /locus_tag="KRN00_003371"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBH1829197.1"
                     /translation="MSEKKVIFSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(4310..5876)
                     /locus_tag="KRN00_003372"
                     /pseudo
     CDS             complement(4310..5876)
                     /locus_tag="KRN00_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(5851..5994)
                     /locus_tag="KRN00_003373"
     CDS             complement(5851..5994)
                     /locus_tag="KRN00_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829198.1"
                     /translation="MYVYYFESPEKFAFNKVIRTKNQNEISLEKFNEFKETIQDKLLP
                     YNR"
     gene            complement(6212..6394)
                     /locus_tag="KRN00_003374"
     CDS             complement(6212..6394)
                     /locus_tag="KRN00_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829199.1"
                     /translation="MKKFRKHKSISNCISILLILYLTLGSLLPNNIYAQDLQSYSGKV
                     CNTTYKAPIERSEGFF"
     gene            complement(6783..7529)
                     /gene="cdtR"
                     /locus_tag="KRN00_003375"
     CDS             complement(6783..7529)
                     /gene="cdtR"
                     /locus_tag="KRN00_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family response regulator CdtR"
                     /protein_id="HBH1829200.1"
                     /translation="MDILIFDNDVCFGMKLKEKINNILIKEGFDNDVVRLYHNANLLL
                     KELTEKNKVRIYFIVVDAKYKISNELCDGLWIAQKIRESDYISPIIFLTNHIEMILGI
                     FDYRLEVMDFILKHDMEIAESKIKACIKIAHKRYIKEKNYRSNFFTIYSDFSLWKISF
                     DEVIYFETSTIPHKIKLVTTSRIFEFYKSLKSLPDLDACFIRVHKSFVVNKYHIVSLD
                     LKKNNIKMSNGHICRISNTYRNILKNIIKT"
BASE COUNT         2738 a          910 c         1123 g         2886 t
ORIGIN      
        1 taataagatt tgatttcaaa gtatttaagg tttattatta aaactgtttt tgaatatgca
       61 aatattttga aaaatatcag tttaataata atgaatctat tttattaatt ttgaaattaa
      121 atttaaaata attaatagag aggggaaatt aaattaggat ggaaaagaaa aaaataggcc
      181 tatggagttt ggtatttatg aatgtatcag ctttatatgg tataagatgg atagctaaat
      241 ctacagcatc aagctttggt ttaggattag gtgcaatacc tatgtggtta ttattctcat
      301 ttatatactt tgtaccagga gctttaattt gtgctgaatt agcttctaca tatcaaaaag
      361 gtgatggagg tctttacgat tgggttaagg aagcctttgg agaaaagtat ggatttttag
      421 tttcttggtt aaactggaca gctaaaatat tttggtattc ttcattttta actttcttag
      481 cagtaaatgt ttcttataca ataggaaatc cagcccttgc tgataataag atgtttgtac
      541 ttatattatc tttaataata ttctgggcat tatctcttat agcaactaaa ggaataagtt
      601 ttacaaaaat atttactaat acaggtgcat taggttcaac aataccaagt gctatactta
      661 taatattttc atttgtagca gtatttgtat tgaaaaaaca tgatatagct tctacataca
      721 caatagcttc aatgactcca aaacttaata tggatgcatt tgttgctata tcagctataa
      781 tgtttggttt agcaggagca gagactgctg ctaacttcat aacagaaata gataagcctg
      841 aaaagaactt ccctaaggca atattaatat cagctggaat agtagcttca ttatatgtat
      901 taggttcaat tgcaataaca atgataatac caccagacca aattactgct tctaaaggtg
      961 tattagatgc actttctgct gtttgtgcgt ctttaggaat tggttcttgg ttggttcaat
     1021 taatagcttt tggtatagct ttttcagtat taggagcaat agttctttac atagcatcac
     1081 caataaaaat gttatttggt agtgttaaaa aaggaatatt tccagatagt ttagtagagg
     1141 taaatgaaca caagatacct tctaaagcag ttatacttca agcaataata gttactataa
     1201 tactattggt gactacatta atgccttctg ttgatgctat atacaatgtt cttgtaacta
     1261 tgacagcatt aactgcatta ttcccatatg tattgttata tgcttcttat attaaactaa
     1321 gaaaagagag accagatgaa attagacctt atactatggc aaaatcaaca agtacttgcc
     1381 taggtttagc aaaaatggtt ttagttgtaa ctgtagtggg tatattatta tctgcagcac
     1441 cagttatgcc tacatttgct gaaaatgtta tatatgagat agagatgatt ggtggaggtc
     1501 ttctagttat attatctggt ctatggttat ggaatagata tgaaaagaaa acagctaaat
     1561 aaaatgtatt ttaaaaattt cttttggata ttataatata tagttgacaa tttatagtgt
     1621 aaggaatatt ataaaataaa gaaattaata aattaaatcc tgagataaga aatagtaaat
     1681 aaatatattt ttgcacagag aattaaggat gctgagaact taataaaaag tatttattga
     1741 atgggtcttt gaggagtaaa atgaaatgta atttaagatt acagagtatt tgatatcgtg
     1801 tatgcacgtt atagcatata ttaagatata tatattcaat tttgagtgta tataaattta
     1861 ggtggtacca cggaaaatat atccgtccta ttgatttagg acggattttt taatatagaa
     1921 aatttaggag gaaaaatgaa cgtaatagga attataggtg caatggatga agaagttagt
     1981 attttagttg atttaatgga tattagagag actataaaaa aagctagctt agaattttat
     2041 aagggaattt tggaaggtaa gaatgtagtg ttagtaaagt gtggcatagg taaggttaac
     2101 tctgctcttt gtgcccagat actaataagc gaatttaagg ttgatgctat tgttaataca
     2161 ggtgttgcag gagctttaaa cgaaaaactt gatgttaatg atatagtaat atcaactgat
     2221 gctatacagt atgatgtaga cactacagca tttggagacc ctaagggagt tataccaaga
     2281 atgaagactt ctgtatttaa agcagatgaa agacttatag atgctgctta caaatcttct
     2341 gtggaagaag taaagactca taaagtatta aaaggaagag tagttacagg agataaattt
     2401 ataaattcta aagaattaaa agaagaatta gtaaatgatt ttggtggata ttgtggagaa
     2461 atggaaggtg gagctatagc tcatgtatgc tatttaaata atactccatt tgtaataata
     2521 agagcaatgt ctgataaggc agatggaagt gctgatgtta cttatgatgt atttgtacat
     2581 gatgctgcca ataactctaa agacatagtt ttaaatatgt taaaatcaat ataaatatat
     2641 aaggaggtac aaaaaaatga gtgaaaaaaa agttatattt agtggtgcac agccatcagg
     2701 caaaatgact ttaggaaatt atttaggagc tataaaaaac tggactgaac ttcaagacaa
     2761 ttatgattgt tattatagta tagttgattt gcatgcaata acagtacctc aagaccctaa
     2821 agttttaaga gccaatacta tagaattact tgctcaatat atagcttgtg gattagaccc
     2881 agaaaaaaat actatattta tacaatcaca tgtcaaagag catgttgaac ttatgtgggt
     2941 attgaatact atgacttata tgggtgaatt aagtagaatg actcaattca aagataaatc
     3001 acaaaagagt gaagcaaatc taaatgcagg tttattcaca tatccagttc ttatggctgc
     3061 tgacatattg ttgtatcaaa ctgacctagt tccagttgga gatgaccaaa aacaacattt
     3121 agaattagct cgtgatttag caaatagatt taataataga ttttcaccta cttttgtagt
     3181 tccagaagga tactacccaa aaggtggagc aagagtgatg agtttgcaag agccaactaa
     3241 aaaaatgagt aaatccgatt caaatgaaaa tgcatttata ctattagcag atgattcaga
     3301 ttctataaag agaaagataa aaagaagtgt tactgattct ttaggtgttg taaaatacaa
     3361 tgatgaacaa ccaggtatta aaaatctaat tgatatatat tctaatttaa gtaaaaagag
     3421 tgtagaagag attgtaaaca tgtatgaagg aaagggttat ggcatattta aagaagatgt
     3481 ggctgaagta gtatcagaag ctttaagacc tataagagaa aaatatgttg accttcttaa
     3541 taataaagat tatttagaaa aaatatatag tatgggagca gaaaaagccg aaaaacaagc
     3601 tagaaaaact cttagaaaag tttataaaaa agttggattt atagagagaa gatactaatt
     3661 attagctatc tttacttgat aaataaattt taaagttatt aaaaaggtat atgatatgaa
     3721 agagagagtc tcaaagtgaa cttttgttca tgaggcactc ttttttgtat gaaataaaat
     3781 atattttaat catttcaaca atgaaaaaga ggattatctc tgttttgaga cagcatcttt
     3841 tgataataaa aaaagatgag cttttgctca tctcaaaggg gttagattat tcttactttg
     3901 gggaaagtag aataaaggta aaagttaact gatgtcaact ttgtcttttt tgcatatcac
     3961 tactgagcat aaaaaaatca gaaaaccata gccttctgaa acaacttcta acatacattg
     4021 tattttatac ccaatatgta atttatgagt taattttaac tcttataatg aaaattgtca
     4081 ataatatatc aaaaaaatat tttttaaatt tatataatta aatgaattta tgtttatata
     4141 taggtgatat gatacagata attatctttt taatacaata tagttctaaa aaagaatata
     4201 ttagaagaag ataatattta aataaaaaat accttataaa gttaattttt taatacttta
     4261 taaggtaaat acatattgta ttgtggggat aaatttaaat catttgatac taatcaacac
     4321 taagaaccaa taactctcta tcatcttgag taattgtata tattcttaat ttcttgtatg
     4381 tcataatatt ttctccacct gtaaaataac tcctaagatt aacacaatca gttttaggtt
     4441 gatttgtatc tcctaaataa ttacgcaatt ctttatcttt agttacaata tctttaaatc
     4501 caaaatattg taaagtagct tcaactctat atttttggac ataatcgaga gcttctttat
     4561 tagtttatgt tggtgtaaaa tacataccat ttatataagc atttattgta cttggattaa
     4621 atttaaaatc tgcagaatat attttatgtg taactattat ttcttgaaca gttggaattt
     4681 taacttctgg ttcattaagt atttcaggag tactatttag ctctgtaata gataagttat
     4741 ctaagtatat tgtatcacta tcaattaatg ttatatctat attagaagaa tctttttcag
     4801 tagtttcaaa ttcataacta aattttgtat atccttgttc tagtaccaaa taatccgttt
     4861 tttcttcttt tacttttata tttacaatta ttgaattata tgttaaagga ttttttgaat
     4921 tttactaaaa acataacgtt tataaggttt tagttcagac ataggtattt taatcttcgt
     4981 ctcaccattt aatctatttg ctgagccttg taaaccatct tgatttgtag tattaacatt
     5041 actccatata ctagggtaat tattgtaatc atcaaaatta gtaaagtaag taggtgtttt
     5101 tataagtata ttcattcctc tttcaagttt aacattacat atttgtttat cagacaaagt
     5161 ttttaaactg tctttaatct tattgctata ttatcatcaa atatgagttc aacacaactt
     5221 tcatctattg gtatattatt aaaatataac aaaccatctt ttttagtagt gccaaaagtt
     5281 ttttcaattg cttctccaat tgtaagttca ggtgttttat cttctgggat ctgtaaactt
     5341 ttagcagtaa ttcttctttt gtaagattca ttttctgtat ctaatataat agatacagaa
     5401 atactgtcaa tttgacctat atcgtcttac caactatttc attctgttac tatttgtcca
     5461 gaaccatttt ttgtaccaaa atttccactt acttgtgttg tttctaattt aatttgcttt
     5521 ccatcatcta atttttttaa ttaattataa tttataggaa tcagtctaga actaaattga
     5581 tacattgtgt taagagccat aggtgaaaat ccttttttga gataagtatt tccaggagat
     5641 agattattgc caatttgatt ttcttgtgct ttgatagttg ataatgcatc tccatctaac
     5701 actaaatttg ttgttggtgt cactttgtac ataggtgcag tacctgtgtt gtagtatcta
     5761 acatttgcat ttatatatgc agattctcct ttgtttatac ttaatccagt atttcatgat
     5821 tatccattgc tattttgaac agcagttgaa ttatctgttg tatggtaata atttgtcttg
     5881 tatagtttct ttaaactcat taaatttttc taatgaaatt tcgttttgat tttttgttct
     5941 tattacttta ttaaatgcaa atttttctgg agattcaaaa taatatacat acataggttt
     6001 atctatttta ttttttgata tagcatttcg aagttctcta tattcttttt ctcaagaatt
     6061 tgcttctatt tgataatcat aaaaataatt tcttgtctga gaatatttgc ttatctctat
     6121 agaatctttt ttatatgatc ctaatacttc tttttcagat ttttcaagtt tttgatcttt
     6181 tctttctcat tctttagcct tttctttatc tttaaaaaaa tccttctgat ctttctatag
     6241 gagccttgta agtagtatta caaacttttc cactatagct ttgtaaatct tgtgcataaa
     6301 tgttattagg taacaaacta cctaaagtta gatataatat caacaatata gatatacaat
     6361 tactaatact tttatgtttc ctaaattttt tcatttattc tccctacaaa tattagttta
     6421 gttaactttt gaattttaat ttatttagat catataatct aaataagaat tttttatata
     6481 aatttcataa aatatgtagg tatatatcat aaaaatatgt atttatatga tatgtcagta
     6541 caaaataaca actgaatatt ttaaagagac tatttcgtac ttttatgatt taatgagcta
     6601 tcttatcgaa tcataatcta ggaacaattg ttataatatc taatagtagt tatatatgat
     6661 atagtcagta tgtgtttttt cacaatatga ttattatata gaggattctt agggattact
     6721 ctttttgtat aaaaaagaga tggttcaaat ttttatcttg agacatctcc tttttctatt
     6781 tattatgttt taataatatt ctttaaaata tttctatatg tattagatat acgacatata
     6841 tggccattac tcattttaat attatttttc tttaggtcga gagaaacaat atgatattta
     6901 ttaactacaa aagatttatg tacacggata aagcatgcat ctaaatctgg taaagacttt
     6961 aaacttttat agaattcaaa tattctagaa gtagtcacta attttatttt atgtggaata
     7021 gtgcttgttt caaaatatat aacttcatca aatgaaattt tccatagtga gaaatctgaa
     7081 tagatagtaa aaaaattaga gcgataattt ttttctttaa tgtatctttt gtgagcaatt
     7141 ttaatacaag cttttatttt actttcagca atttccatat catgttttag tataaagtcc
     7201 ataacttcta acctataatc gaagatccct aaaatcattt ctatatgatt tgtaagaaat
     7261 atgattggac taatataatc tgattctcta attttttgtg ctatccataa tccatcacat
     7321 aattcattac ttatcttata ttttgcgtct acaactataa aatatattct tactttattt
     7381 ttttcagtaa gctcttttaa taacaaattt gcattatgat ataatcttac aacatcatta
     7441 tcaaaacctt cttttattaa aatattattt attttttctt ttagtttcat tccaaaacaa
     7501 acatcattat caaagattaa tatatccact aaataccctc ctataaaaaa ttcaaaagta
     7561 aaaaaacaaa agtattttat agaaaataca taaaataaca ctaggagata aataagatta
     7621 aggatagtta gaattaaggt atatttatgc ttgttta
//
LOCUS       DAEQAF010000137         7643 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.141, whole genome shotgun sequence.
ACCESSION   DAEQAF010000137 DAEQAF010000000
VERSION     DAEQAF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7643
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.141"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            16..1074
                     /locus_tag="KRN00_003376"
     CDS             16..1074
                     /locus_tag="KRN00_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBH1829201.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGFYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1178..2362
                     /locus_tag="KRN00_003377"
     CDS             1178..2362
                     /locus_tag="KRN00_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBH1829202.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHVCKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2569..3282
                     /gene="rpsB"
                     /locus_tag="KRN00_003378"
     CDS             2569..3282
                     /gene="rpsB"
                     /locus_tag="KRN00_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBH1829203.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3361..4272
                     /locus_tag="KRN00_003379"
     CDS             3361..4272
                     /locus_tag="KRN00_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBH1829204.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4357..5061
                     /locus_tag="KRN00_003380"
     CDS             4357..5061
                     /locus_tag="KRN00_003380"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBH1829205.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5087..5644
                     /gene="frr"
                     /locus_tag="KRN00_003381"
     CDS             5087..5644
                     /gene="frr"
                     /locus_tag="KRN00_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBH1829206.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5647..5850
                     /locus_tag="KRN00_003382"
     CDS             5647..5850
                     /locus_tag="KRN00_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829207.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5879..6613
                     /locus_tag="KRN00_003383"
     CDS             5879..6613
                     /locus_tag="KRN00_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBH1829208.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6626..7405
                     /locus_tag="KRN00_003384"
     CDS             6626..7405
                     /locus_tag="KRN00_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBH1829209.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3144 a          784 c         1455 g         2260 t
ORIGIN      
        1 ggaggatata tatttatgaa ttgtaaatgg atatctaaaa tagatgagag aaaaaaatgt
       61 catagagaag cagattcttc tggatattgt atctttcata aagaaaataa gtctgatgaa
      121 gagatacaat tgatgatgga tactcttcat aaagaagaga taagtgaatt taatggattt
      181 gtttttgaaa atgaatttaa tgcggaagaa atattaactt acaattataa aatactggat
      241 ttttctgaat ccatatttaa acaaaaagca aattttaaaa aatatatttt taaaaagaat
      301 attattttta actatacaga atttagagat aaagttttat ttaatggttg tgtattctta
      361 gaaaactgtg attttaatag aaccatattt agtaaacact atataaatga ccgtatattt
      421 gaaaaagtga aatttaaagg acctgatttg gtagttaata aagtagaaaa ttttccacga
      481 atggatggaa taatttttag catgtgtaca aaatttgtgt taaagaatgt tgaatatgga
      541 aaaagtgagt atgagcatgg caagataaat tatagaatag ctagaaatca agcaacaaaa
      601 attggagaat atgagatgat aggattttac tattataagg aaagaattta tagtagtaaa
      661 ataatgaaac gttctaatta tcctaccttc agtgattatt tagttgaaaa attttttgac
      721 caaatagcac gttacacaac aggttatgga gaaaagccat ggaatatatt attagttatt
      781 atagcaataa taagtgtttt tgctttatta tacttatttg taggcataga aagttcaaat
      841 agcacacttg tagctttaga tataaataat ataggtgatt actcactaag tgagattttc
      901 aaaatgtata tggatttatg gtattttagc atggctacat ttagtacagt aggatatgga
      961 gatatggttg ctacaagttt gattgggaaa gcattggcag gtatagaagt attttttgga
     1021 gttacaatag gagcaatttg ggcatctgtg attattaaaa gaatgataag gtaatatttg
     1081 tgtaaatatg gataggtatt aattactaga tataaattgg actaaatagg gaaaatttaa
     1141 atataaatat acttaataat ccaagaaggt gaaaaatttg aaaaatgcac taaaaaaaat
     1201 tatatcatta gccatgattc tagtttttat aataccaaat tattcatatg cagatgataa
     1261 atctgtagac aagtattcaa aaacatctat acttatagac caagaaacag gtagagtttt
     1321 atatagtaaa gaacctgata tgaaggtacc attagctagt ttaagtaaga tgatgacttt
     1381 tttacttgca atagaagcta ttgaaaataa agaagtaaaa gaaactgata aggtaaaaat
     1441 agacaaatct attgcatcag taaaagggtc aagttataaa cttaaagatg gtgaagaagt
     1501 gccacttata gagcttatga gaggtcttat gattgtatca ggaaatgatg cggcaattgc
     1561 tatagcaaaa catgtttgta aaacgaaaga agcatttgta gatagaatga ataaaaaagc
     1621 aaaagaaata ggaatgagta atacacattt tctaaatcca aatggtcttc caatatacga
     1681 tttaagcaac cccaaaaaac cagcaaaaga aaatatctct actgcaaaag atatagctat
     1741 tcttggaaaa tacatgtttg accattatga aaaacaagta acagctataa ctgatatgga
     1801 gacatataca aattcagata gaagttttga aaaaagcaat acaaatgcat tattaagaat
     1861 tataccagaa gtagatggta taaaaactgg atatactggc aatgctggat attgcttatc
     1921 attttctatg gttgtaaata aaaatgataa aaatgagaaa aaacgtagag taataggggt
     1981 tgtattaggt actaaccata aaaataaaag aacctctgct tcattagctc tactgaaata
     2041 tggaaaagaa aatttcaata tgaaaaaagt aattgataaa gatagcttta ttggtaagaa
     2101 atatataaaa ggaatgaaag agttagaggt tacattaaaa gcaaaagatg aactttatac
     2161 aatattaaaa gatgatgaaa gtataaagtc agaagttaag attaaaaata tagagtaccc
     2221 tgttaaaaaa ggtgatacta tgggtattat aaaatattat actaattcag gtgacttact
     2281 tggaagtgta gatatagtaa gtaataatag tatagataac gtatcattaa aaacaaaatt
     2341 aaaaatgaaa tttgcaaatt aaattcaaaa aatggtataa aatacacaaa aaaatataaa
     2401 aatagaaaat atggaaaaaa tattgttatt tcttcacctc tgtgatatac tactagaggt
     2461 gaaaaaataa aataaatcac acacagcatt gggatcctta aaaggtgcct attacatggt
     2521 tttttaggga gaagatcaag ctggaggtat aaaaccagga ggtaagatat gtcagtaata
     2581 tcaatgaaac aattattaga agcaggtgtt cactttggtc accaaacaag aagatggaac
     2641 cctaaaatgg ctaagtatat attcacagag agaaatggaa tatatataat cgacttacaa
     2701 aaaacagtta aaaaagttga agaagcttac aagttcacta aagaagtagc tgaaacagga
     2761 aagccaatct tattcgtagg aactaaaaaa caagctcaag atgcgataaa agatgaagct
     2821 gaaagatgtg gaatgtactt tgttaatgaa agatggttag gtggaatgtt aacaaaccac
     2881 aaaactataa aaacaagaat aaataaatta agagaattag aaaaaatgga agaagaaggc
     2941 gtatttaatg ttcttcctaa aaaagaagtt ataaaattaa gagctgaaaa agaaaaacta
     3001 gaaaaatact taggtggaat aaaagacatg cctgaattac caggtgcaat gttcgtagtt
     3061 gacccaagaa aagaaaacat agctattcaa gaagctcata gattaggtat accagtagtt
     3121 ggtatagttg atactaactg tgacccagaa caattagact ttgctatacc aggaaatgat
     3181 gacgctataa gagccgtaaa attaataact ggtgctatgg caacagctgt aattgaaggt
     3241 agacaaggtg ctgaggaaga agtagctgaa gaccaagaat aataatttga caattaaatg
     3301 gtaagggtcg cccttaccat ttataatatg gaatagaata agtaggagga aacttaaaaa
     3361 atggctaata taactgctca aatggtaaaa gagttaagag aaagtacagg cgcaggaatg
     3421 atggactgca agaaagcttt acaagaagct gaaggaaaca tggaaaaagc agtagattta
     3481 ttaagagaaa aaggattatc aaaagctgct aaaaaagctg gtagagttgc tgctgaaggt
     3541 ctagttgcaa tagaaatgaa tgatgataat acagttgctt ctatggtaga agttaactca
     3601 gagacagatt tcgttgctaa aaacgaagac ttcaaagtgt tcgttaaaga tgctgcttgt
     3661 atggcattag ctactgataa agaagatata gcttctttat taggtgaaac tcataaagag
     3721 ggaataactt tacaagaagt tttaaataat agagttgcaa aaataggtga gaaattagac
     3781 tttagaagat ttgctaaagt tgtaactaat ggacaagttg ctggatacat tcacggtggt
     3841 ggaaaaatag gtgttcttgt tgaaatggaa acagaagcta gagatgctaa agttttagaa
     3901 ttaggtaaag atgtagctat gcaagttgct gctatgaatc ctaagtatgt ttcaagagat
     3961 gaagtagatg ctgaatacat agcacatgaa acagaagtat taactcaaca agctttaaat
     4021 gaaggaaaac cagctaatat agttgaaaaa atggttaaag gaagattaga aaaagaatta
     4081 aaagaggttt gtttattaga gcaaactttc gttaaaaatc cagatataac tgttaaacaa
     4141 ttagttgctg atgttgctaa ggcagtaggt tctgatataa aagttgttaa agttgtgaga
     4201 ttcgaagttg gtgaaggtat acaaaagaga gaagaaaact ttgcagaaga agttgctaag
     4261 caacttaagt aataaccaaa gagagaacac gcaggtgttc tcttttttaa aaaatagaaa
     4321 aaattggata tgaaggattg aaataggagg tttctgatgg ataaaccaat gtacaaaagg
     4381 gtattgttaa aattaagtgg agaagcatta gcaggagaaa gaggttttgg tataaataat
     4441 gatgtagtta atgatattgc tattgctata aaaaaaatac aagaaatagg tgttgaagta
     4501 gctgtagtag taggtggagg aaacttctgg agaggcagaa ccagtgaagg aatggacaga
     4561 actactgctg actatatagg aatgttagct acagttatga atgcaatggc gctacaggat
     4621 gcactagaaa atatagatgt tgctacaaga gttcaaactg ctatagacat gagacaaatt
     4681 gcagaaccat atataagaag aagagcagtt agacacttag aaaaggaaag agttgttata
     4741 tttggtgcag gaacaggaaa cccttacttt acaacagata caactgctgc tttacgtgct
     4801 gctgagatgg aagcagaagt tatattgtta gctaaaaatg ttgatgcagt atatgacaag
     4861 gatccaaaag tacatgcaga tgctaagaaa tttacagaat taagttacat ggaagttata
     4921 cagaaagaat taaaagtaat ggattctaca gctacatctt tatgtatgga taataaaatt
     4981 ccaataaagg tatttgagct tacaacagag aatataataa gagcagtaaa aggcgaaaat
     5041 ataggaacta ctgtaaaata atgaagaatg aaggaggagt aaaattatga aactggaaat
     5101 acataagcaa ttagaagaga aaatgaatgg gacaattgat gctttaaagt ttgaatttgg
     5161 aactataaga gcaggaagag ctaatgcaca aatgctagac aaaataagag ttgattatta
     5221 tggaactcca actccaataa atcaaatagg tgctatatct gtaccagaac caagaatatt
     5281 aatgatatct ccttgggata aatctgctat gcatgaaata gaaaaagcga tagctaactc
     5341 agacttagga ttaaatccat caaatgatgg tgaggttata agactttctg tacctgcttt
     5401 aacagaagaa agaagaaaag aattagctaa aaaagctagt aaagctgcag aagaatttaa
     5461 agttagaata agaaatgaaa gaagagacgc caatgagaaa attaaaaaga tggaaaaagg
     5521 cggagaatta actgaagatg aattaaaaaa agcacaagat gaagttcaaa aaatgactga
     5581 taaatttata aaagaaatag atacattatt atctaaaaaa gaaaaggaca taatggaggt
     5641 ataatattga aaaaatatta taacctttta ggtcttcatg tagatgaggt aaaacaatat
     5701 tttgatgagc aaaatataaa ttataccgta aaatctattg aaggtaaaaa ggataaagaa
     5761 aaacttgtag ttcctagagt tataaaaata tctgagatag gtgatagtgt agaactgata
     5821 atcacatact tttctgactc cttagtttaa ggagtcagaa caatattgga ggcaaaatat
     5881 gaataacaac attatatatg atatagactt aaataacata cctactcata ttgctattat
     5941 aatggatgga aatggaagat gggcaaaagc tagatttctt ccaagaactg caggacataa
     6001 ggctggagta gaaactataa gagatatagt aaaagaatgc tcaaaattag gtgttaagca
     6061 cttaacatta tatgcatttt caacagaaaa ctggaaaaga ccgaaacttg aagttgacac
     6121 acttatgaac ttattatcta catacttaag aaatgaaata gctgaacttc accaaaacaa
     6181 tgtaaaagta actgctatag gagatataag tgctttacca aaaacttgta taagagaatt
     6241 aaactcagct aaggaactga caaaaaacaa tacaggagtt aacttaaatt tagcattaaa
     6301 ctacggaagt agagcagata taaaaaatgc tcttatagat atagtaaaaa attgtgaaag
     6361 tggtaaaata gatataaaca atattgatga agatattata aaaaactatt taagcacaaa
     6421 gtctatacca gatccagact tggtaataag aacaagtggt gaacaaagat tgagtaactt
     6481 tttactttgg gaagttgctt attctgagtt ttactttact gatatacatt ggcctgattt
     6541 taaaaaagaa gaactacaga aggctatata cgtatatcaa agaagggata gaagatttgg
     6601 aggacttaag taaggagatt attttatgct tacaagaatt attgcttcac tagctctggt
     6661 tccattattt ctatttgttg tatatggagg tattcctcta tatatagctg agacagcaat
     6721 agtttatatt gcattgcatg agttttataa ggcatttaaa ataaaagatg tacatccaat
     6781 attcattata ggatatttat tttctattta tttagctgta aaaaatattt ttaatttacc
     6841 attagaatat acttatgcag taatttttat tttattttta gcaagtataa tttatatgtt
     6901 gatgggcaaa aacaatgtta tagatgtttc gattacgttt ttaggagttt tttatatagg
     6961 agtattttta gattttataa ttataactat aaatggattt gaaaaaggta gtatatatgt
     7021 atggcttata tttgtgatat cttttatgac agatatattt gcatatttta gtggttattt
     7081 acttggaaaa cataagctaa ttcctaaagt tagtcctaaa aagactatag aaggagctat
     7141 tggaggaata ataggaagta cactttgttg tattttattt ggatatttat ttggcattga
     7201 tttgcttcaa ttagcgataa taggaagtat aggaagtgta atagctcaat taggagattt
     7261 atttgcatct tctataaaga gatatgtagg gataaaggat tatggaaaga taatacctgg
     7321 tcatgggggt atattagata gatttgatag tgttatatta gttgcacctt ttgtatatag
     7381 tgcgattaaa ttttttatta gataaagatt ggttggattt aaaagagcaa tctataattg
     7441 ctagtaatga aaatagctat gtaactttta aatgcagaga tattctgcag ttattagtta
     7501 catggctatt ttcattgttc aaaaatttag aagaccttgg ggaattgtat aagaataggt
     7561 attactttat aatagtatac tatatttgta gtgagtatat tttttatact ataactatca
     7621 ttaaaaaata tttttttgtt taa
//
LOCUS       DAEQAF010000138         7488 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.142, whole genome shotgun sequence.
ACCESSION   DAEQAF010000138 DAEQAF010000000
VERSION     DAEQAF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7488
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.142"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            61..1038
                     /locus_tag="KRN00_003385"
     CDS             61..1038
                     /locus_tag="KRN00_003385"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBH1829210.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTEFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWDSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            1031..1999
                     /locus_tag="KRN00_003386"
     CDS             1031..1999
                     /locus_tag="KRN00_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBH1829211.1"
                     /translation="MYNNILDIEGLKVGQVEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKKTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            2183..2773
                     /locus_tag="KRN00_003387"
     CDS             2183..2773
                     /locus_tag="KRN00_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBH1829212.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            2792..3562
                     /locus_tag="KRN00_003388"
     CDS             2792..3562
                     /locus_tag="KRN00_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBH1829213.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            3699..4667
                     /gene="dusB"
                     /locus_tag="KRN00_003389"
     CDS             3699..4667
                     /gene="dusB"
                     /locus_tag="KRN00_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBH1829214.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            4776..5255
                     /gene="greA"
                     /locus_tag="KRN00_003390"
     CDS             4776..5255
                     /gene="greA"
                     /locus_tag="KRN00_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBH1829215.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            5270..6799
                     /gene="lysS"
                     /locus_tag="KRN00_003391"
     CDS             5270..6799
                     /gene="lysS"
                     /locus_tag="KRN00_003391"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBH1829216.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            7108..7302
                     /locus_tag="KRN00_003392"
     CDS             7108..7302
                     /locus_tag="KRN00_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829217.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
BASE COUNT         2982 a          758 c         1518 g         2230 t
ORIGIN      
        1 tgtataatta tttattagaa gaaaataagt catgaaatta tgtcatatta gaggtgaaat
       61 atgagagata aaataataga gattatatta aataataaat ctgaatttat ttcaggagaa
      121 gaattatcaa aacaattagg ggtgtcacgt gcagctatat ggaaacatat gaaagcctta
      181 aaagaagagg gatataatat agaatctgta aataaaaaag ggtatcgatt agcggaaaat
      241 ccaactgatt tattaagccc acagaatatt tactataaat tagatacaga gtttattgga
      301 aaaaatattg aacatcttga cactatagat tcaacaaatg aacatgctaa aaggatagct
      361 ataaatagtg tagatgggac tgtgatttta agtgaacatc aagatatggg gaaaggacga
      421 ttgggaagaa gatgggattc aaaacctcat gaaggaatct ggatgagtat tatattaaaa
      481 ccagatatgg aaccattcaa agccccattt ataactttaa tagcaggagc aagtgtaacg
      541 aaagctttaa acaatctagg agcaaataca ttaataaaat ggccaaatga tgttatttta
      601 aatggaaaaa aaatatgtgg tatattaaca gagttatctg ctgaaattga aagaacaaat
      661 tatgttgttc ttggaattgg aataaatgtt aaaataatgg attttgaaca agaaatagct
      721 gacaaagcca catcattgta taaagaaggg tatatgttat ccagagtaga tattgttagg
      781 aatgtattga ctgaatttga aaaattatat ttagattata ctgtaaataa ttccaaagaa
      841 aaaaccttaa aaatatgtag agattattct gcaattatag ataaaaatat atatgtatta
      901 aaaggagata atagagaact agtgaaatgt ttagacataa atgaagaggg aaatttatta
      961 gttcaaagaa gtgatggaag tataaaagaa attatttcag gtgaagtttc tataagagga
     1021 gaaaaaggat atgtataata atattttgga tatagaaggc ttaaaggttg ggcaggttga
     1081 ggatagaaat ggtcttactg ggtgcacagt agtaatatgt gaagaaggag ctacttgcgg
     1141 tgttgatgta aggggctctg ctccaggtac tagagaaacc gatttattag accctgtaaa
     1201 tatggttcaa aaagttcatg cagtagtttt ggctggaggt tctgcatatg gtcttgaatc
     1261 cacttgtggt gtaagtagat acttagaaga aaaaggaatt ggatttgatg taggtgtagg
     1321 taaagtgcct atagttgtag gagcagtttt atttgattta ggagtaggga gctttaaatg
     1381 tagaccagat ttaaagatgg gttatagagc ttgtgaagtt gcaaatactg atattttaaa
     1441 tcaaggaaat tatggagcag gttgtggagc cactgttgga aagataagag gtcaggaata
     1501 tgctatgaaa ggcggaatag gtagctattc tataaaatta gataatggtc taattgtatc
     1561 tgcattaatt gctgtaaatg ctcttggaga tgtttatgaa aatggtaagg ttatagctgg
     1621 tgctttaaat gataaaaaga cagaaacaat tgatacatat aaattaatga aacaaggtga
     1681 aagtaaaggt ggatttagtg tagataatac tacaattggg ataattgcaa caaatgctaa
     1741 gttaaccaaa gctggatgta aaaagatatc tcaaatggga catgatggat atgctaagtc
     1801 tatttttcct atccatacac ctcatgatgg agatacaata ttcacaatat caacaggaga
     1861 aatagaagca gatataacat tagtaggttc attggctgta gaggttgtgg aaaaaagtat
     1921 aataaatgca gtaaaaaaag cggatagtgt agaaaatata atggcatata aagatatagt
     1981 aaaaaaacga gaaatatgat gaaattagca tatttttctt gtcaaattgt tgacaatggc
     2041 aactcatctt gataaaatta ttcttgttag agcgggcatc ctacaatggt agcttgactc
     2101 atagttataa gaaaaaaacg aaaaaaatta aaaaattaag tagtccggca tcttaatgag
     2161 ctggaacgga ggtgtatttt ttatgatgaa cacaagtgca tcagtaagaa aagtaaatgt
     2221 aagaaagatg actataatag gagtactatc agctatttct attatgctat ctatgactcc
     2281 attgggattt attccagttg gacctacaaa agcaactata atgcacatac cagttattat
     2341 tggagctatt atggaaggac caatagttgg ggcagcaata ggatttatat ttgggatatc
     2401 aagtctctta aatgctataa caaacccaac agtaacatct tttgttttta taaatccatt
     2461 agtttcaata ttaccaagag ttatgatagg tgtattagct tattatgtat atcagttaat
     2521 aattaaggct acaaataagg tatacatatc aggtttaatt acaggggcaa taggttctct
     2581 gttaaataca gctggagttt taggaatgat atatgtctta tatgctgaca agtatcttca
     2641 tgcaatgggt aaaagtggtt cagcaggaaa agtaataatg gctcttgccg cagcaaatgg
     2701 ggtgccagaa gcaatagtag gggctttagt agtagctgct gttgccactg tacttaagaa
     2761 aagcaaaaaa tagaaagaag gttaatgaca tatgcttcta gtatttgatg ttggaaatac
     2821 taatatggtt ttaggtatat ataaaggtga caaattagtt aattactgga gaattaaaac
     2881 agatagggaa aaaacgtctg atgaatatgg aatcctgata agtaacctat ttgattatga
     2941 taatgtgaat ataagtgata ttgatgatgt tataatatca tctgtagttc cgaatgttat
     3001 gcattctctt gaaaactttt gtataaagta ctgtaaaaaa cagccattaa tagtaggtcc
     3061 aggcataaaa acaggtctaa atataaaata tgataatcca aaacaagttg gggcagatag
     3121 aatagttaat gctgtagcag ggatagaaaa gtatggagca ccaagtatac ttgttgattt
     3181 tggaacagca actacatttt gtgctatctc tgaaaaaggt gaatatttgg gtggaacaat
     3241 agcaccagga ataaaaatat ctagtgaggc gttatttcaa agtgcgtcta aattacctag
     3301 agtagaatta gctaagccag gtatgactat ttgtaagagt actgtatcag ccatgcaatc
     3361 tggaataatt tatggatatg ttggtttagt tgacaaaata ataagtatga tgaagaaaga
     3421 attgaattgt gatgatgtta aggttatagc tacaggtgga ttagctaaac tgattgcttc
     3481 agagacgaaa agtatagatt atgtagatgg ttttttaaca ctagaaggat tgagaataat
     3541 atatgaaaaa aaccaagaat aattaatata cagggaattg ggttatatat ccaattccct
     3601 ttttatgata gatttctagc tatatgtggt atattataat gaggaaataa gaatttaaag
     3661 ttaaatcaca aaataaaggc aaaaatagga gaaaaacaat gaaaatagga aatttagaat
     3721 tgaaaaataa agtttttcta tcacctatgg caggtgtaac agaccttcca tttagattaa
     3781 tttgtaaaga acagggatgt gggcttttat atacagaaat gataaatggt aaggcacttt
     3841 gctatgatga tgaaaatact aaaaaaatgc ttaagataga agaggaagaa catcctgtag
     3901 cagttcagat attcggttca gaaccagagt ttatgggaag agcagcagag ataatgaatg
     3961 attattcaaa tgagattctc gatataaata tggggtgtcc agctccaaaa gtagttaaaa
     4021 atggagatgg ttcagcactt atgaaaaatc ctaagcttgc agaagaggta ttgagggcag
     4081 tagtgaagaa ctcaaaaaag ccagtgactt taaagattcg aaaaggctgg gatgataata
     4141 gtgtaaatgc tgttgaaata gcaaagatag cagaggattg tggaataagt gctttagcaa
     4201 tacatggaag aactagagaa cagttttata caggcaaagc agactgggat ataattgcag
     4261 agattaagaa aaatttgagt atacctgtta taggaaatgg tgatgtattt acaatagaag
     4321 attcaataaa tatgttagac aaaactggtt gtgatgctat aatgataggt aggggtgctc
     4381 aaggtaaccc ttggatattt aaaagaataa accattatat gaatacaggc gagattttgc
     4441 cagagccaac tcttaacgaa aaaataagta ctgccattaa gcatttaaaa cttgcagtag
     4501 aagaacatgg agagtatgta gctgtaaggg aaatgagaaa acacatcgct tggtatttaa
     4561 aaggacttag aaactctgca aaattaaggg atgaaattaa caaaatagaa gactatcaag
     4621 aagttgtgtc gaaattggag tactatatgg aagactcctt gacataaaaa taatagtgac
     4681 ttataatata gcgcataaat taaaaaaaga ttataaaatt tttaaaatat aattaggaaa
     4741 attcctaaga aatttgtgaa ggagttgtat ttataatgga agaaaataaa gagtttttat
     4801 tgacacaaga gggatatgat aaattagaag aagaattaga aaacttaaag gttgtaaaga
     4861 gaaaagaagt tgcagagaga ataaaagttg ctatatcttt tggtgattta tctgaaaatg
     4921 ctgagtatga tgaagctaaa aaggaacaag cacaagttga agaaagaatt ttaaaattag
     4981 aaaatatggt tagaaaagct gttatcatag atgaaagcaa aatagacctt aatgttgtta
     5041 caataggatc aatagttaaa gttaaggatt tagaatttga tgaagaggtt gaatatacta
     5101 tagttggttc gacagaagca gacccatatg atggtaaaat atcaaacgaa tctcctgtag
     5161 ggaaagcact tttaggtaga gctgcgaaag aagttgtgga agtgcaagtt cctgatggag
     5221 ttgctaagtt tgaaatatta gaaataagaa gataatttgg aggaaaaaaa tgaaaaataa
     5281 tcaacaaagc aatgaagaag cgcaaattca agaagacctt agtgaagtac ttcaagtaag
     5341 aagagataaa ctaaaaaaat tacaagagtc aggtagagat ccttttaaag aaagtagata
     5401 tgatagaact cattattcta tggatataaa agataacttt gattctcttg agggtaaaac
     5461 tacaaaaata gcaggacgta taatgagcaa gagaatacaa ggaaaagctg gctttataga
     5521 tattcaagac caagagggaa gaatccaatc ttatgtaaga ctagatgcta taggagagga
     5581 agaatatagt gtattttcaa catatgatat tggagatata gttggaattg aaggagaaat
     5641 ctttaaaact aaaaaaggtg aaatatctgt aaaggctaaa tctgtagtat tactatgtaa
     5701 atctttacaa gttttaccag aaaaatatca tggattaaaa gaccaagaac taagatatag
     5761 acaaagatat gttgacttaa tagtaaatcc agaagtaaaa aatgcttttt taattagaac
     5821 aaaagcatta aaagcattaa gagcatactt agatgataga ggatttttag aagttgagac
     5881 tccaatatta aatactatag caggtggggc aaatgctaga ccatttataa ctaatcataa
     5941 tactttacat ataccaatgt atttaagaat agcgaatgaa ttgtatttaa aaagacttat
     6001 tgttggtgga tttgataaag tttatgaaat gggaagaatg tttagaaatg aaggtatgga
     6061 tttaaaacat aatcctgaat atactgcaat agaattatat caagcatatg cagactatac
     6121 tgatatgatg gaaataacag aaaatgttat tgcacatatg gctgaagttg ctacaggaag
     6181 tatgatagtt aactatcaag gaacagaaat aaactttaca ccaccttgga aaagaatgag
     6241 tatggaagat tgtgttaaag aatattctgg tgtagatttt tctactataa atacagatga
     6301 agaggcacta gaagttgcta gggaaaaagg tatagagata aaacctggaa tgagaagagg
     6361 ggaagtaata aatgctttct ttgaagaatt tggagaagat aaattaatcc aaccaacatt
     6421 tataactcat catccagttg aagtatctcc attatctaag agaaatgttg aagacccaag
     6481 aagaactgat agatttgagg catttgctaa taagtgggag ttagctaatg cattttctga
     6541 acttaatgac cctattgacc aaaaaggaag atttatagac caattaagaa aaagagaatt
     6601 aggtgatgat gaagcttttg aaatggatga agatttctta aaagcattag aggtaggtct
     6661 acctcctaca ggaggactag gaataggtat agatagagta attatgttat taactaactc
     6721 tccatctata agagatgtat tattattccc gactatgaaa cctattgata acaatccaaa
     6781 taaagaagaa gaaaactaag aaatattagc attctactaa gttttaaata aagtttagct
     6841 attaaattat caataaatag ctaaatttta tttaaaatgt cagtgtagaa tgctttttat
     6901 atgcttcaaa gattctttta gatatttaat ttataaatta ccaacaaacg ttagaaattg
     6961 atattagttt ttgttgattg agactttata tttagaaaat atgattgaaa gtaatttatt
     7021 atgaaaatat ttagaataat ttatgagaag gtaaaaagaa taatttatga gaatactata
     7081 tataaaaaat tattggggga atgtctgatg tttcaagtaa ttaatttttt atgtttattt
     7141 tgtgttggat ttttggttct tgatgttatg atatattttt gtaaggatgc aatggatatt
     7201 tttgagggta caactaatgt taataaagtt aagagtataa atgtttgggc agatagagtg
     7261 agagctaatt catattctta tgaaaataaa attgcaaaat aggtaaaatt atatatgcat
     7321 gcattgtttg taatatcaag ggttatatct attagtttta attatattta ttaaaaaaaa
     7381 ccaaaagtta taaccttttt taaaataaaa aacaaaaaaa gtattgacga attattttta
     7441 aggtgatata gtattacttg tccttaagaa aagggcaaac ataaaaaa
//
LOCUS       DAEQAF010000139         7244 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.143, whole genome shotgun sequence.
ACCESSION   DAEQAF010000139 DAEQAF010000000
VERSION     DAEQAF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7244
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.143"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            467..976
                     /locus_tag="KRN00_003393"
     CDS             467..976
                     /locus_tag="KRN00_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBH1829218.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            1004..1198
                     /gene="rpmI"
                     /locus_tag="KRN00_003394"
     CDS             1004..1198
                     /gene="rpmI"
                     /locus_tag="KRN00_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBH1829219.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            1254..1610
                     /gene="rplT"
                     /locus_tag="KRN00_003395"
     CDS             1254..1610
                     /gene="rplT"
                     /locus_tag="KRN00_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBH1829220.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            1920..2465
                     /locus_tag="KRN00_003396"
     CDS             1920..2465
                     /locus_tag="KRN00_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829221.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            2467..2558
                     /locus_tag="KRN00_003397"
                     /pseudo
     CDS             2467..2558
                     /locus_tag="KRN00_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002605025.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
     gene            2900..4825
                     /locus_tag="KRN00_003398"
     CDS             2900..4825
                     /locus_tag="KRN00_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1829222.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLSKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWTINDKFSKTIEVE"
     gene            5226..7130
                     /locus_tag="KRN00_003399"
     CDS             5226..7130
                     /locus_tag="KRN00_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBH1829223.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAESRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDGEDLSSSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT         3052 a          722 c         1362 g         2108 t
ORIGIN      
        1 tagtacatta gagtacaata tagaatttgt tatgtagtat agtagtatat tagaatacaa
       61 tatagaattt gttgggtagt atagtgttat attagaatac aatataggat ttgttatgta
      121 gaatatatag agtcatgtag aatatacata tataaaagga ttttgggtat aaatttaaaa
      181 attaatagca aaatgagtag tatagacata taattagtag taggaagtaa ttaaattttt
      241 cctaaacaaa aaaaatagtt gcaaataatt tgattaagtg atatagtaaa taaggtaaga
      301 ataaaacaaa gaagaagtcc gcttctcacc ttacgccgga ggttagtaag gtaaatataa
      361 gttaaagctt aattttaatt taagtttgtt taaatttggt aacttatatt gcggatgatt
      421 acgtcatccg ctttttattt tataaaaatt ttggaggtgt cctacaatta gcaaagaatt
      481 agcaatcaat gaacaaataa aagataagga aataagagtc ctttcaccaa caggtgaaca
      541 acttggagta atgcctacta aagaagctca agcaatggct aatagcaaaa acttagattt
      601 ggttcaaatc tcgccgaatg caaatccacc agtatgtaag ataatggatt atggaaagtt
      661 tagatatgag caagcgagaa aagagaaaga agctaagaaa aaacaaaaaa ctatagttgt
      721 aaaagaagta agacttagac caggtattga acaaaatgat ttaaatacga aagctaataa
      781 tgctataaag ttccttaaaa aaggggataa agtcaaagtt gaacttagat ttagaggaag
      841 agaattagga cataaagaca taggtaaaga agttatgctt aagtttttag atataataaa
      901 agagtttgga gaaccaacaa aagcccctgc atttgagggt aataatatgg ttgtaattat
      961 agatccaaaa aaatagatga ttaactgaga ggaggaattt gtcatgccta aaatgaaaac
     1021 tcatagaggt gcagcaaaga gattaaagaa aacaggaact ggaaagttaa agagagcaaa
     1081 agcttttaaa aaacatatat taactaaaaa atctgcaaaa actaaaatga acttaagaaa
     1141 atcaacttta gtaagtgatg gagatgctaa gagaatagca caattattac catactaaga
     1201 tacagattgt aaataataac tatagaagag ggatataaaa ggaggtcata acgatggcaa
     1261 gagttaaaaa agctatgaac gctcgtaaaa agcataagaa aatattaaaa cttgcaaaag
     1321 gattcagagg atctagaagc aaattatata gaccagcaaa tacattcgta atgaaagcat
     1381 taaaaaatgc ttatatagga agaaagttaa agaagagaga cttcagaaaa ctttggatac
     1441 aaagaataaa tgcagctgct agaatgaatg gaatatctta ttcaagatta atgaatggat
     1501 taaaattatc tggtgttgaa gttaacagaa aaatgttatc tgaaatggct atacaagacc
     1561 cagaaggatt tgcaaaatta gcagaagttg ctaaagcaaa attagcttag tattgaatca
     1621 tgagatgtaa agtctttgag ttatataaat aattcaagga cttttttatt ttttgaaaaa
     1681 tacttattag tgttatgtac aaccaatttt ataatgataa ataaaataag caatacaata
     1741 gaattttatg agatttatta taagaattgt tacaattatt tatgatagct ataaaaagtc
     1801 atagtaaaaa tgatattgat gtatgttgat atatgtataa agctttcaat caatcttgaa
     1861 ttaatattat caacatgata atattatctt attaataata taaataaggg ggagataata
     1921 tgaatgaaaa actaatggat tgttttgtaa acccaattaa atgcaagtta ttgattgaaa
     1981 ttttttcaaa taatcgaact acagctaaac aattaggaga aaaatttcaa gatatatcaa
     2041 aggcaacact ttatcgttac cttaataaaa tgttgaaaga tgatattata aaagtagttg
     2101 aagaaaataa aataagggga actgttgaaa aagtatatgc tatgaagtta gatatagctg
     2161 atgatgtgaa caaaattata gatgagaact ctggagaaga atatgctcaa ctgtttactc
     2221 aatatatgat gggattttta agagaatttt atgaatacgc tgaaagaaag gaaaaggata
     2281 tcttaaaaga tggttcagga ttttctgtct gtccagtata tgctagtatt gatgagatag
     2341 ttgaagtgag taaaaaaatt gctagtatac tagaacctct aagaaataac tcacatgaag
     2401 aaggtagaag aatgcattct ataggagtga taatcactcc acctaaagag gatgaaggga
     2461 aataaatctg atttacatgg ggtagagcca atttatacag ggaatcgttt tatgatttac
     2521 atatgtatcc agagcaaagt atctctgctt ggattgtact tcattgtacc atttcatcca
     2581 atgacttgga gtggtacaat gaagtttttt aatttttcat attaatgcta aagaaatgaa
     2641 ctttagacca catatgcaat taggttgcat tatacaatta gaccacatat acaaaataaa
     2701 aatcagtatt tttatagcag ataaattgac tgttattctt cttaaaaatc atctattagt
     2761 tattgttagc atattgaaag aaattatagt aatctattga ataaatgaat attgcccata
     2821 atcatataaa ctgctatagt ttaaaataaa gcaggacgtt aaattttata gtaatctaaa
     2881 aatttaagag ggggatttta tgaaaataaa atttgttatt atgccattgg tgatattttt
     2941 aatggtatta tttgtggggt gtcaaagtac aaaagataca gaagttaaag caaaagatac
     3001 agaaattaaa atattaggga caggtgattt gcattcaatt ttgacagact ctatggtttc
     3061 atatgtaaat gaggaaaggg aaaagaataa aaatctgctt atggtagatg cgggagattt
     3121 ctatggtaca caaagtagag aaatgtggga atggtcttct ggaaaaaagt taattaatat
     3181 taaaagaaat ggtagagcag agtatgatga cataattaag agtagtaaag atgaagtacc
     3241 tatagttaaa gatatggcaa agttgaaata tgatgctgta gttttgggag ataatgaatt
     3301 tgtttcaaat gataagcaaa gtcttgataa actggtttct gattttaaaa ataataatat
     3361 gccattggta tcagcaaata tatatgaaca atctggagaa aattatgtac aaccatatgt
     3421 aatgaaaaat attaagacag atgagggcaa tgtaaaagtt ggaatactag gtcttactat
     3481 aaaagaagta ggggaaaccc ttggtcttga ggattttgaa aaggataaaa aagctagaga
     3541 gcttggagaa caagctgatt acaaaggaaa attatatgca aatgatttag tagaagatgc
     3601 aaagaaatgg ataaaagtta tggaaaaaga aagtccagac ataatagttg cagttgtaca
     3661 ctcaggggaa gaacctaaaa cagatagaaa tccaggaaat agaataaaag agttagcaac
     3721 tacagtggat ggaatagatg caattgtagc tggtcatact catgaaaaaa tagatgaaca
     3781 caaatataaa aataaatctg gagatgaagt aattgttaca caaccaggtt ggcatggaga
     3841 tagagtatca gagattaatt tcaaattaag taaagagaat ggaaagtggg acataaagga
     3901 aaagtctagc aaattaaaaa taattgataa agaagtaagc atagttgcta ctgcagattt
     3961 acattcacat ttctctgata aattaacagt tgaccttgtt aatgaacgta gtaacccaat
     4021 tgaacctgtt gtagtagatg caggcgactt cttagaccct caaacagatg aaatgactca
     4081 atggtataaa gagtggaaaa gtataagaga taataatagt gataaaacga ttagtagatg
     4141 cccaatggtc atggatatga atcagggaat gtatgatgca gtagtacttg gaaatcatga
     4201 atttgtatct gaaaaagatg aattttggtc agatgaacgc cttttagatg ctgttataga
     4261 ggattttgaa caggtggcaa tttctgtgtt atcggcaaat atatataggc aatctggtaa
     4321 aaattatgtt aaaccatata ttataaaaga tgtggagacg agtgaaggta atgtaaaagt
     4381 aggaatattg ggacttacta taaaagaagt aggtaaaggt cttaaaaatg taaacttaca
     4441 agagcaattt caatataagg ataaattgta tgcaaatgat ttagtggaag atgcaaagaa
     4501 atgggtaaaa gttatgaaaa agaaaaaacc agatataata gttgcagttg tacattcagg
     4561 agaagaacca aaaaatccaa aacatccagg aaatagaata aaagaactag caactacagt
     4621 agatggaata gatgcaattg ttgctagtca tactcatgaa aaaatagatg agcatgaata
     4681 taaaaataag tctggagaaa aagttatagt gacacaacca ggtgagcatg gtaaatatta
     4741 ttctaaaatt acctttaaag taaataaaga aaagggttcg tggactatta atgataaatt
     4801 cagtaaaaca attgaggttg aataacttta taaaatttat agataaagta aattatctga
     4861 tattgacatg atatataaga taaagtttct aatattagta taatgcataa tgtgaaatat
     4921 tttaataata agagaataaa caagacaaat aaaaatattt taacatgtaa gatatagtat
     4981 gaactattat actaatgctt actttataat ttgaacatat tagaataagt cttatttgaa
     5041 aattttagtg tattagagta agtattattt taccagtaaa aaatattgag aactatatgt
     5101 agatttgctt aaaaaggaat ttacatatag ttcttttcgt ataataaata gtacaatctt
     5161 atatggtaaa gataaagtgt gatattaaat tttattatca tccaaaatct aaggaggagt
     5221 ctcttatgaa aataaaattt attatagtag catcaataat atttttaata gtattacttg
     5281 tggggtgtca aagcactaaa gatacagaaa tcaatgtact cgccacaagt gatttacatt
     5341 caattattcc agataattta atttcctatg tagaagagga gagaaaatat gatgagaatc
     5401 tacttatggt agatgcagga gatttttttg acatgcaaag tggtgagatg aataagtggt
     5461 ttactggtca aaaattagta agatttaaag atgggatacc agagtacaaa aaaatagctg
     5521 aatcacgtga aggagaagtt ccattggcta aaaaaatggc aaagctgaag tatgatgcag
     5581 ttacatttgg gaatcatgaa tttgtatcta atgacaagca gagccttgat aaattggttt
     5641 ctgattttaa aaataacaat ataccattag tatcagcaaa cgtatatgaa caatctggag
     5701 aaaactacgt aaagccatat gtaatgaaaa atataaatac tgacaaggga actgtaaagg
     5761 ttggtatact tggtctgact ataaaagaag taggggaacg ttcaaggttt aaaagttttg
     5821 aacaagataa aaaggctaga gaacttgggg aacaacctca atacaaaggg aaattatatg
     5881 caaatgattt agtagaagat gcaaataagt gggtaaaggt tatggaaaaa aaagaaaagc
     5941 cagatataat agttgccatt gtacattcag gtgaagagcc aaaaaatcct aaaaatccag
     6001 gaaatagaat aaaagaacta gcaacaactg tagagggaat agatgctatt gtagcaggtc
     6061 atacacatga aaaaatagaa cagcatacat ataaaaataa ttctggtgaa gaagtaatag
     6121 taacacagcc tggagctcat ggtaatagta tatcaaagat taattttaag ttggataaga
     6181 agaatgataa gtggtttata aaagacaaat atagtgaatt aaaggttttt ggaaaggaag
     6241 taaatataat tacaacttct ggtctgaatc caaaattttc agatgaaatg gcagttaatt
     6301 tgtttaatga aagagataga gatgttcaac ctatctttat agatactgga gattttttaa
     6361 atactaatac aaaagaaatg actaagtggg ctaaagagtg gcaatacaat gaaaataaag
     6421 gcatctataa aaaaataaat gaatggccaa ttgtatatct tggttatgat gctgtagtac
     6481 ttggtagcca tgaatttaca gaggataaag agacttttga ggaaaaaaaa tctacattgg
     6541 attatattat agaaaacttt gaagaaatga agataccagt attatcagct aatatatatg
     6601 atgaatctgg agaaaattat gtaaaacctt atataattca taatgtagaa actagggaag
     6661 gaaatataaa ggttggagta ttaggtctta ctactactga taaggatgga gaagacttaa
     6721 gtagctcaag tttaagcaaa gactcaaaga cttcgaaaat tcctgaagaa acaggaaagt
     6781 tatatactaa caatctagta aaagatgcaa gcgaatgggt aaaagttatg caaaaggaaa
     6841 gtcctgatgt gattgttgca gttgtacatt cagataataa tagtactcta aaaaatccaa
     6901 gtagtgaagt caaaaaactt gcaatgtcag tagatggaat agatgctatt gttgtaggtc
     6961 atacgaaaaa taaggtagaa gaacatattt acaaaaataa gtctggggat gaggttatag
     7021 taacacaatc tggagaagat tgttattcaa aaataagtct tgaactaaga aaagaaaatg
     7081 gcaagtggaa tatcataaac aaatatagta aagcaataaa aatgaagtga atttattgat
     7141 atataaacca ttattaatac tgatttttat aatataataa atactgattc tacaatataa
     7201 ttaacactga tttttataat ataataaata ctgattctac aata
//
LOCUS       DAEQAF010000140         6667 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.144, whole genome shotgun sequence.
ACCESSION   DAEQAF010000140 DAEQAF010000000
VERSION     DAEQAF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6667
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.144"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(661..1068)
                     /locus_tag="KRN00_003400"
     CDS             complement(661..1068)
                     /locus_tag="KRN00_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829224.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1542..2426)
                     /locus_tag="KRN00_003401"
     CDS             complement(1542..2426)
                     /locus_tag="KRN00_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1829225.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEIE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(2717..3193)
                     /locus_tag="KRN00_003402"
     CDS             complement(2717..3193)
                     /locus_tag="KRN00_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBH1829226.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDENCGCGCNHHHEN"
     gene            3460..4635
                     /locus_tag="KRN00_003403"
     CDS             3460..4635
                     /locus_tag="KRN00_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBH1829227.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(4716..5519)
                     /gene="proC"
                     /locus_tag="KRN00_003404"
     CDS             complement(4716..5519)
                     /gene="proC"
                     /locus_tag="KRN00_003404"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH1829228.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAALIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5559..6143)
                     /locus_tag="KRN00_003405"
     CDS             complement(5559..6143)
                     /locus_tag="KRN00_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829229.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
BASE COUNT         2192 a         1130 c          747 g         2598 t
ORIGIN      
        1 cactgctatc acctcgcttt aattgttttt tgatacactt tttaatgatt ttatcacatt
       61 ttatcacatt taatatatta tataatgctg tggtgaacaa tttattaatc acctatcata
      121 atattaacaa atgtaattat ttaaaacaat tatttagaag gttttatatt taattttaaa
      181 taacatattt aagaaccgta agtcttaact tttatcattt ttgaggttgt cgttcacata
      241 agttcgctac tacctatgca gttctcttat gaacttctta cactttcatg taagcacaga
      301 ctatatctta tccttcagca ttatccgtta aggtctaccc acttccacta ccaatagctt
      361 gtagtgtact tccctcaaga ggaatagtcg ttgaagtttc tcctattcgg agtttacctg
      421 ctgattgccc attttaaagt acttaggatt taaccttata ccatctaacc aattttttct
      481 actttcgtaa ctttcacact taggtttatt tcatccttat gttttagttt gattagcttt
      541 aggggtttcc agcaattcaa gtagtattgg ataggttcta tcctatctct acatataggt
      601 ttccctatat gctgactatt ttagctacta actcatgact aaagtcacga gtgtgcgtag
      661 ctatttttta atcaatattt tagtaaattt tacggtaagt aaaaacctct ctccttcaaa
      721 tcctatagca aatatactta caagttgctt tgagaaaata actcctaata tagctacaac
      781 tatgcatata ccaactatta tatttaaaac attgtttaaa aactttagtg cttgcttttc
      841 accttgttta ctacttatat cttgatacat tggaataaaa gtagtaacta tagcagtacc
      901 tattgctgca aatataatat ttggtatatt catagctgtt aaataactct ctgtatataa
      961 gcctgtacca taaattgatg ataatactaa ttctctaccc attccaagaa tcttagagat
     1021 tatagtaact atcatcaaat aaaaagttgc tttagctacc ttgctcattt tatcactcca
     1081 cttctaacat acctcttttt aatcaagtaa aatttagctc attagatata attctatcaa
     1141 ctaatttgcc ttgcttagcc ctatcaaaat ataattaaca cctatttctt aatatatcac
     1201 aaactacatt attcttcata tttttttatt tctccaataa gttttacatt tttcctatat
     1261 aaattgtata gcttcaatta tattcaaaga aatggagttg ctacccgata actttaaaag
     1321 taaaaaacag attttattat ctttttaaac tatattctaa catattttgt ccatattgag
     1381 aaattttact aaactattat gtactttatt aaataaataa aataacagca cacctataaa
     1441 atacaagtgt gctgttcata aacagatttt ataaaaaaat aattcctaag tagagattaa
     1501 catgctttct catactctca tatataatgt gtctaaaaat attaataaaa atgctttaat
     1561 tgttttaact tacttggatg tcttaatttt cttattgctt tagcttctat ctgtcttatt
     1621 cgttctctgg taactccaaa tacctttcca atctgttcta gtgttttagg gtcatcatca
     1681 tcaattccaa atctcattct taaaacttgc tgttcttgct ctccaagacc tgtaagtagt
     1741 tcttctatct tttcttttaa attatgctgt tcaacttcgt gtattacaac atctttaaaa
     1801 tcagcatctg atggtataaa ttcaactaaa ctactatcct catcttcttt taatggagta
     1861 tccaaagata caacattttt atctcttctt aataattcca acactttgtc aacttctaaa
     1921 ccacatgcat ctgcaatctc atctatagtt ggctctctta ataatacatt taaaagttct
     1981 tgtttctttt tctttacaaa atttattctc tgatgaagat gtataggtat cctaatagta
     2041 ttttcgcaat cgtcgatata tcttgttata ctttgtttta tccaccaagt tgcataagtg
     2101 ctaaatttgt atcctttttt ataatcgtac ttttctacag cttttataag tcctatattt
     2161 cctgcttgaa ttaaatccaa catatcaata ctatctcttt tatatctctt tgctatgctc
     2221 actaccaacc tataatttga atttataaat ttttcttttg ctactgaaga tgagttgatt
     2281 atttccttag ccagctctat ctcttctcct gctgacaaca ttttgtattc ctctatttcc
     2341 tttaaataca ttttcatcgc atttgataca tttgatgaac ccacacaaat ataattttca
     2401 taattatttt cttttttagt atccataatc aaaccccttc tattcataga atttgctaaa
     2461 acaaaaataa ataatttaaa cctacataat ctacaattac ataatatccc attctttaaa
     2521 tgaattgttt tgtatattat gtatacaaat ttataaaaac tatacctata atattattct
     2581 acttctaaca gcaatatcct ccttatatat ataatttatt ttattatatg ttgttatatt
     2641 cttagttttt tgaatgatat atgtctaaaa aaagactgtt tactaaacag tcttttttta
     2701 tatatatgct caatatttaa ttttcatgat gatgattaca tccacatcca caattttcat
     2761 catggtgatg atgttcttct aaatcttttg cctgttgttc catttcatga aactctttta
     2821 ccattatatc ataagttgga agagctgcct cagtatcgta ttcttcccct ctccaatcag
     2881 cgtacatcat agcatctcca ttagttaaaa ccaatctacc tgacatagtt atattatcca
     2941 cttcttctaa aaattctatt tgtttttgta aaacttctcc ttctaactcc acatcttcat
     3001 ctaaacattg cactatcatt acaggtgcat aataatcttc ttcatcttta acatttacaa
     3061 caatatctaa aattccttct gcaccttctt caaattctgc caactcaaca tttgtatcaa
     3121 tcatatcttg aggtactaat aaatcttcta ttaaatattt tattactcta tcttttacta
     3181 attcttttga catttatttt tctccttccg attctataac attatcataa tcatttctat
     3241 attatagtat actacattaa ttgttttttc aatctcttac aaaaattatt tttttattat
     3301 cttccttata ttcccttttt tattacaaag ttgtaatcgc attgatttaa aaaatagttt
     3361 atatttagta taatagaaat gtagcacata tttttattca atatattaat aaaaaaatat
     3421 attgaaaatg taatgtatgt taaatctagg aggaatatta tgaagtttaa aaaacaaatt
     3481 agttctattg ttgtgtctac tatgcttgta cttgggagta tgaacctttc ttatgcagac
     3541 ggtacaaatg tagttacact tggagctaac ttatcagagt ctcaaaagca gcaaatgctt
     3601 aattactttg gagtaaaaaa agaccaagtc ttagttttag atgtaacaaa tgcagaagaa
     3661 agacagtatt tacaaggtgt tgcaacagag ggtcaacttg gaaaagttac tatctcttgc
     3721 tcatacgttg aacctactaa aaaaggaaat ggaattaatg ttaaaacagc aaacttaact
     3781 tgggtaacta gttcaatgat tgcttcaacc cttacaacag ctggtcttga agatgcaaat
     3841 gttattgctg ctgctccata tcctgtaagt ggtactggag cattgacagg aatcatgaaa
     3901 gcatttgagg atgcttcagg aaagaaactt gatgaaacta agaaagaaat tgcttctgaa
     3961 gaattggtag ttacaggtga cttaggagat gatatagggc aagaaaaagc aacaggtgta
     4021 atgaatgata taaaaacaga aattgtaaag aatggtacaa aagataccaa tcaaatagca
     4081 aatacaataa ataatgttgt aaataattac aatattacta ttacaccaga acaaaaagaa
     4141 caaattaaag gtgtaatgaa aaaaatagct gaccaaaatt acgattacaa tagcatgaaa
     4201 aatacactag ataatgtatc agataatgta aatgaacaat taaagaaatt aggtgaaagt
     4261 gttaagggtt ctggtatact agatactatt ggtggatggt ttagtggaat aggagactgg
     4321 ttctctggtt tattctcagg cggagataaa aaagatttgg gaatcttaaa taacactaat
     4381 gatgagtctc ttggctctga tgctgtaata aattctacag aaggtgttca aataaatcca
     4441 caaaataata ctaattctaa caatgatagt gatacaaata gctcaaaaaa tgatacttca
     4501 agtaataatg aaaataacga tagttctcaa acaaatgaaa acaacacaac aaataattca
     4561 gaaaatcaat caaataataa tgactcagtt ggtttctttg aaaaaataaa aaattggctt
     4621 tcaggcttat tttaaaaatt aaacaaataa aaagaattgc ctaaaatgga aattttctat
     4681 aaaaggcaat tctctttatt tacaataaat ttttattact cactcatttt tttagatttt
     4741 tctatacatg cacatattgc ttttatcaca gaagctctaa aaccttcttc ttcaagtact
     4801 ttaactgctt ctatagtagt tccaccaggt gaacatacca tatcttttaa ttcaccagga
     4861 tgttttcctg tctcaagtac catttttgca gaacccataa cagcctgtga tgcaaactta
     4921 tatgcttgtg gtcttggcat tcctgcaatt aatgctgcat ctgctatagc ttctataaat
     4981 aaaaatacat atgctggtgc agaaccactt gcaccaatta cagcttctat aagatactct
     5041 ggtactacct cagtatttcc aaaagaatta aatacttctg taactgcttc taagtcttct
     5101 ttgtttatat ttttatttat agaaagagaa gacatggctt catttacaag agctggagta
     5161 tttggcatag ttctaactat ttttttatct tctcctataa tagactctat atcttttata
     5221 gattttcctg ctgctattgt aactataatt ttattgtcat ctataaagtc ttttatctct
     5281 tccaaaatat catcatatat atctggttta acagctacaa ttactatatc agaggttcta
     5341 gttacttcct tcgagtcttt tgtagtattt attccaaaat ttgcatctat tctatcgaga
     5401 gttccttgac tatatgctga tgctataacc atattaggtt caactaattt tgaatttact
     5461 attcccccta tcatagcgct tgccatattt cctgcaccta tgaatccaat ttttttcact
     5521 ttagtacctc cttattgact aatagtaatc gttaaaattt aagcttcttt aactgcatca
     5581 gacttttcaa atggatttgg tatacttact accaaaattt tcactacctt attagtatag
     5641 ttgacccaat tatgattgtt cttttcacta ttatagtgta ttgtgtctcc tggatacatt
     5701 tctatttgtt catctcccaa aaacactgta agagtaccct ctaatacata cacaaactcc
     5761 tcaccttcat gtacgtaaca acaaatttcc tcactactct tacttggaag aatttcaatt
     5821 aatcttggta gcattgtttt ttcctttaaa ctagatgata aatgataatg tataaatgtt
     5881 gagttttcta catcaaatac ttctttttca taacttctta atacagctct tttatgctct
     5941 tttggcttca taaaaaagta agttaattct acatctagta cacttgctat ttttcctaag
     6001 gaatctgttg ccacacttgt taatcctctt tcaagttgtg ataaaaaacc aattgacaag
     6061 tttgtttttt cactcatatc cttcagcgtc atttgctttt gagttctgag ttgctttatt
     6121 tttgctccta tgtccttatt caaaaccatc acccctaaat aattttaatt ttttcataat
     6181 ataaatacaa aaatataaat ataggtactg aacctatctt tatttcattt aaaaaaattt
     6241 ttataagtat tactataatt tatcaatctt tttttgtcta catttttacg attatttacg
     6301 atttattttt cacatatgta tatttaatct tgccaactaa agatacattt tttataagca
     6361 tttactcttt atataataaa acttaagttg ttcatgtagt cttcttctgg tttaattatt
     6421 aaaatttcaa attatattat tatttctaca cattattaca tcctttagta caattataac
     6481 ataattttac aatttaatga tatctattca atgtcttttt ttactctaca acatatttta
     6541 ttttagagtt taatactata tatatttttt atatacagcc ttgtcatttt ttagattgtc
     6601 aagagttatt gaagtatttt atgtagattt agattttatt ttctaatttc tcatttaaca
     6661 agaattg
//
LOCUS       DAEQAF010000141         6657 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.145, whole genome shotgun sequence.
ACCESSION   DAEQAF010000141 DAEQAF010000000
VERSION     DAEQAF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6657
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.145"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(362..619)
                     /locus_tag="KRN00_003406"
     CDS             complement(362..619)
                     /locus_tag="KRN00_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1829230.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            1199..1420
                     /locus_tag="KRN00_003407"
     CDS             1199..1420
                     /locus_tag="KRN00_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBH1829231.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKNKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2069..2299
                     /locus_tag="KRN00_003408"
     CDS             2069..2299
                     /locus_tag="KRN00_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBH1829232.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            2312..2461
                     /locus_tag="KRN00_003409"
     CDS             2312..2461
                     /locus_tag="KRN00_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBH1829233.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            2718..3155
                     /locus_tag="KRN00_003410"
     CDS             2718..3155
                     /locus_tag="KRN00_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBH1829234.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSTPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            3412..4305
                     /locus_tag="KRN00_003411"
     CDS             3412..4305
                     /locus_tag="KRN00_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1829235.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLVQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNVQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            4483..5307
                     /locus_tag="KRN00_003412"
     CDS             4483..5307
                     /locus_tag="KRN00_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1829236.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAKTDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            5406..6014
                     /locus_tag="KRN00_003413"
     CDS             5406..6014
                     /locus_tag="KRN00_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBH1829237.1"
                     /translation="MGKFLRGKIMKSDSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            6118..6294
                     /locus_tag="KRN00_003414"
     CDS             6118..6294
                     /locus_tag="KRN00_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829238.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
BASE COUNT         2568 a          802 c          813 g         2474 t
ORIGIN      
        1 aatttaacaa ctaatacctt aaaatatcta tttatattct taattttata aatatattat
       61 gtcatattaa ttgctatttc tttatttata tagtttattt atttattttt cccctttata
      121 caagcaattg tatcatttta tctatttttt agccaacaaa tattttcgac cattttcttt
      181 gtattctcaa tatatctcca gtatttaaca aattttttta tagaatatac aatgtattta
      241 aattaataag tagtaaattt agttaatttg tctaaaaaaa ctttataaaa catcttcttt
      301 gtctttactc ttacgtttaa caaggctatt ttcattatgt ttaaacatta ttttattata
      361 tttaaacact attttcattg agtattcgct taatattgct tacacacata ttatatctaa
      421 tagccaattc attgtggttg actccattaa attgttttac tatatcccta tttctagcat
      481 atctaaaaag ccccttatac gtaggtatat aagtatttgt tcctccatac aacttggcaa
      541 cctctatgaa cttatcaatt ccgattattt ctaccattgc atgaaattga actggtatat
      601 cctccacttt tatcttcata agttacacct cctttaagat atttttatag acttaacaaa
      661 gtttttattt aatacattat tgactaaact atatttatta gttttattga atctaataaa
      721 aaatttctta gctttaaaat taatttttgt attaacttta ataaaatttc tcataactta
      781 taactttgtt agctttaata aagattttaa tggtttaaaa gtaaaatgtt aatattggac
      841 ttttaacttt tttatttaca gattaaattt aataaaattt ttaacataag ctttaacatt
      901 taatttaaca taaactttag tacctaacat ttaactctac acatatgaaa atccatacaa
      961 aactatctca actaagcatg aatatataca aatactattt caaaacacta agaacatatc
     1021 ttcacaaata acttgtaaac tttttcatca gcaaaaaagt aaaatttttc ctataaaaat
     1081 ttacacaaaa aatctttaga aattactgtt taactccgat attatcttag atgatagtat
     1141 tatagctaac aaagaaagtc gacaaatctt tgaaattaaa tttttaggag gtaattttat
     1201 ggaagttgtt tcaacaaaaa atttatctag tataaaacta aaattggatg ctggttttga
     1261 tgataagggt aaggcagttg ttaaaaataa atcatttgca aatgtaaaag cagaggcatt
     1321 aaatgaagat gtttatgctg ttgcagaagc aatagcaagt cttcaagaga accctattgt
     1381 agatatttta aaattagata gtacatcact atctaaatag tatcttttaa acgtactctg
     1441 ctttacaaat taaaaaatta actctttata taaaagatta agttatataa cgtacttaat
     1501 acgctataga tttggcagat tataacttca attttggtta taactttaat atattaacgc
     1561 tttgaaaaat taatatatta aacgtatttc aacttaaaca tgttagctat tttagatgct
     1621 accctacttt aatctaatta attgaaataa attaaatatt ttctatatca gcaataacta
     1681 gagtcaacaa ttaaaatact aatattgaca attgaaacac tgatactaac aaacaaaaca
     1741 ctaatattga caattgaaat actaatacta acaagcaaaa cactaatatt gacaattgaa
     1801 atattaatac taacaagcaa aacactaata ttgataatta aaatattaat actaacaagc
     1861 aaaacactaa tattgacaat taaaatatta atactaacaa gcaaaacatt aatattgaca
     1921 attgaaatac taatactaac aagcaaaaca ctaatattga caattgaaac actgatacta
     1981 acaaacaaaa cactaatatt gacaattgaa atattaatac taacaagcaa acaattaaaa
     2041 tataaattat tatatcggag gtaattatat ggaaattaag aaaaaattag tcatgagctt
     2101 taaaaatgta aaggataaac aagtttcttt ttctatagaa aatccaaagg atgatttaac
     2161 tgaagaaaat ataaaatctg tcatggattt gatagtatct aaaaatattt tttcggttgg
     2221 aggatttgac ctagcttctg tggttgaagc caaggttgtg gaaacaaata ccactcctta
     2281 tgacttagtt atagaatagg gggctaattt tatggatgat agtttacaac tgttaataac
     2341 caatgttggt tttcctatag ctctatccat gtacttattg gttagaattg agggtaaatt
     2401 aaatacttta tcaaacagta ttgatacatt atccaaaaat attttgatat ttaagaagta
     2461 atttgacaat atatgtaagt cataaaatag gtctatttgt aaaataatta ggcatattct
     2521 atgcgaaata ctaggatatt tggataattt atccaaatat ccatagtatt tttttgaatt
     2581 ttaccacctc aaatttgaat ttcactgttt tatttttgaa tttcactatg cttaatttga
     2641 aatttagaac gcatctagtt ggactcaata agatataatg ctattctaat gacagtaata
     2701 aaatgaggtg atgattaatg aaaatacatg tcgaacaagg tattaattgt gatgatattg
     2761 aaataaccat aaaatgttct gctctagata ataacattga aaaaataatt tcattattga
     2821 gtacaccgtt acttgatata aaaggtaaaa aatcaggaga gatttataag ctcaatgtct
     2881 gtgatatttt atactttgag acagttggaa ataaaacatt tgcttattat gaagatgatg
     2941 tatttgaaat tgatttaaaa atatataaat tatcaaaatt attagctaat acatctttct
     3001 cacgaatatc taaatccatg attttaaata tggactacat aaaaagtata aaagtaatat
     3061 cacataatcg catgcaagct actttaaaaa acaacgaaaa agttattata aatcgtcgtt
     3121 atataaaaaa tattaaagaa aagctaaaca tttaataaaa atctaaagta atttattaat
     3181 atcactaatt gcaaatttat tgacctattt aataattaat aataatataa tatattcaat
     3241 attaaatact aattaattat atttagtgta aaaataatta atcaaaatat aaaaaatagg
     3301 atattattat aggcaataac taacatcaag cgataactta atacatataa aaataaataa
     3361 acaattaata aaaattaaaa cttcattata aaacggaagg atagtgaaaa aatgcaacta
     3421 tataacaccc cctttaatac aaacaaacac ttaatctatt tctttacatt tacgctagta
     3481 ttgaactgga tattcagtct tacacctgcg ttacttggaa ttacaaatac aatacttgga
     3541 gaaatcattt tttatcttgc atatacatca ccagctattg taggtctatt ttttatttct
     3601 acaatctatc cacaaagtgc aaaacaagat tttatttata gatacctaag ctttaaagaa
     3661 atcggaataa aatggatact attaacaata ttattttttg ctttaacttt tattacttcg
     3721 ttaataatcg gaaattactt taatgtaaaa acttctgata tagattggat acatatagca
     3781 gtgtttagac cttctaaaat agcttatatg ctattagcaa gttttatatt gagtatactt
     3841 agtcaagaag ctggatggag aggatacgcc attgacaaat tattagttag atttggattt
     3901 ataggttctt caattatttt agggcttgtt tgtggaatct ggtatctagg gtcgtatttt
     3961 acacctaatc aaataccata taatttggta caatactccc tatttgatgc ttttttattt
     4021 ataccaaaca ttgtactttt aaactttata attaattttg tatatatcaa tacaagtaga
     4081 agcattttat cagctgggtt agttcatatg atgtactatt ttttcaacgt tcaattactt
     4141 ctacactacc ctattaaatt atgtgtaata gctcaatatg tacaaataat atttggttta
     4201 atatttcttg tatatatgat ttcttctaat aaatttaaac agaaggtaaa ttctgaaatt
     4261 gaacagataa agtcggatga ttttgaattt gagttagact ggtaatttta atatgaatta
     4321 taaattaaga taatctatga tttgatacga ttactactta aatataattt actctctata
     4381 atttattgca acatctggaa aataattgta tttccacaaa cgcttgaagt atataaaaac
     4441 aaaatatata ctgattataa gtgaaaagga ggtcatattt tcatgtttaa aataggagag
     4501 gtttcaaaac taacacaaat ttctattcgt atgttgcgtt attatgatga acttggtatt
     4561 ttaaaacctg caaaaacaga caaatataca ggtcatagat tatactcagt tgaacagatt
     4621 tcaatattac aaagaattgt attattgaga gattcaaaat ttagcgttgc agaaatagca
     4681 aatatcgtac ataattggaa tgatgaattt gtaattaagg aattgaatag aaaaaagaat
     4741 gaaatacaaa aggaaataaa gcaggaacaa caaagaataa ataaaattga taaatttata
     4801 gaagctataa actgtgataa agatgaaatt cattacaatg ttgtctttaa aaagattcca
     4861 agttataaaa tcatatcact tagagagata attccagact accaatctga aggtatactc
     4921 tgggaaaagc tatctaaatt tatcaaagaa gaacatatag aagtatcacg tcaatccaac
     4981 aataacatag ctttttacca tgatgaagaa gtcaaagata acggtgtaga tattgaagtt
     5041 ggaatggttg taaagaagat tggaaagaac aaatctggat ttatatatcg tgagacagaa
     5101 gaaattgata tgatggcatg tactatggtt tatggtccat atgaaaatat agctggtgca
     5161 tatgaatcgt tctgttattg gttagataaa aatagtgatt atcaaatatc aggtataaat
     5221 agacaaatcg gtcataaagg tgaacataat gaaataaatc ctgaaaatta tcttacagaa
     5281 attcaaatcc cccttataaa agtctaatcg attagtactt aaatacttaa gtactaatca
     5341 cccattgaca tcccaaaatt ttcatgatag tatctaaacg tgtattaaac atgtttaatt
     5401 tttttatggg gaaattttta aggggaaaaa ttatgaaatc agattcaaca aaggaacaat
     5461 taattaatgc tacaatccag ttactatctt cacatagaga tgtttcaagc attacggcta
     5521 gagaaattgt agctaaagca aatgtcaatt tagctatgat taattattat tttaaatcta
     5581 aagaggagtt aattaatatt tctattaaaa aatttttaaa gcgtcatatg gatgaatata
     5641 aggctacaca tgatactaaa aatttagcac ctaaacagca attaagggaa atactaattg
     5701 cattttttga ttttataggt gaacatagtc aatttataaa gatttctgta ccctatatat
     5761 tgatacagga agaaattgtt tatccatttg agatactacc tttaattaag gctcactatg
     5821 aaaatcagaa taacaaaaaa actgaagctg aatacagaac tattgcgtat caaataactt
     5881 catttattca gttgcttttt cttcgttcta atgctttttt caagtatagt ggtattgata
     5941 ttcttaatgt tgaacagaga aatggtttaa tagattttca attagattta ttattggtag
     6001 atattacaaa ataatactat attaattttt tatgtacatt tttttatttt atggtaacgt
     6061 ttgaaaatat tctcattgac taaaaatact tgcattaaat aagggggagg aattttaatg
     6121 ttttttacat ttataggagt aatatcagca attttattgt tgtgtacaat tatatgtggt
     6181 ttatggataa aacttaataa tcgtaataat gactctaatt ctcactttac tttttcaata
     6241 ctttcaattg ctttttcact gttaattgtg gtggcctttt tagtaagaaa ttaatgtctt
     6301 tgttatgctg gggtttatta ttatagattt ttattattgc attattttta ctatattata
     6361 gtatttttat tatattacag ggtcttattt attatagtgt tttgttgtta cagcatttta
     6421 ttatattaca gagtcctatt tattatagga tttttattat attgtaaaat cttatttatt
     6481 ataggatttt gttatattac aatctcttat ttattgcagt gttttgttat tacagtattt
     6541 ctattatatt gcaaactctt atttattatg gtgttttgtt attgcaacat ttctattata
     6601 ttgtaaagtc ttatttatta cagttcttta ttatactaca gacttttatt attacaa
//
LOCUS       DAEQAF010000142         6478 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.146, whole genome shotgun sequence.
ACCESSION   DAEQAF010000142 DAEQAF010000000
VERSION     DAEQAF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6478
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.146"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            233..3412
                     /locus_tag="KRN00_003415"
     CDS             233..3412
                     /locus_tag="KRN00_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1829239.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGIDKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNIKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            complement(3697..4461)
                     /locus_tag="KRN00_003416"
     CDS             complement(3697..4461)
                     /locus_tag="KRN00_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBH1829240.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIIDFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(4617..4850)
                     /locus_tag="KRN00_003417"
     CDS             complement(4617..4850)
                     /locus_tag="KRN00_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829241.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            complement(4924..6417)
                     /locus_tag="KRN00_003418"
     CDS             complement(4924..6417)
                     /locus_tag="KRN00_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1829242.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVNLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELTDIEQSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
BASE COUNT         2414 a          907 c          742 g         2415 t
ORIGIN      
        1 aagaatattt ttaataataa gattttatat ttattaataa tctatttata taattatttt
       61 tcattcatag tttataagat aattcaataa aaatctaata gtaaattgtt atttacacat
      121 atattgtgat agataaaagc tattcatatc tgccttaatt ttagtcttaa atttagagtg
      181 taaattgaat gcatttagat tataatatat acagtgaggt aaggtgaata atatgaaaat
      241 agatatgata tataaactaa taagaagaaa tacagaacca tcaagatggt caagaggtgt
      301 aaaatattat actaatcaat tagttgatta tatagacata gatattgatg acctacaaaa
      361 taacctgttg acatttcgtg gtggagtcaa ttctgaagat aattatagct tttattttaa
      421 ttcaataact atagatataa agcactttaa gataattgaa aatgattgta gttgcgctga
      481 ctgtcaatca aagggcaaaa gtatttttat atgtaagcat atagttgcta ttgtgataaa
      541 aagcttaaaa caaataaaaa ataaaaaaga tgttcctcct attctaatag atatattagg
      601 tgcagataag gataagcttt ctaatacaaa ttctaaaacc agcttagatt taagcaagca
      661 attactttct ttgttagaca atactaaaag agaaagggtt aatttagatg tattgataaa
      721 tgtggattca aataaagcaa ttgctgaatt taaaatagga attgataaaa tgtacatttt
      781 aaaaaacatt actgaatttg catattcaaa acttaatgga tatgaattag attttgggaa
      841 gaaatttact tacaacccca acactcatta ttttgctgat gaagatgaga agttagtaga
      901 tattatagaa gaatatggga caaatctttc atacaacttt tcttcatcac attcaaaaaa
      961 atttatggag ataaatgcaa gctctttaaa acaattttta aatgctatta agtacaagga
     1021 ttttaccctt attttttcta aagaggaata tcatccaaag atattaaatg atactctacc
     1081 tgtaaggttt gattttaaaa atatagaaga taaaatagtc ttatattcta aagattcact
     1141 acctgttcca cttactaaaa aaaatgatgt acttttatat gatggcaata tctatttatt
     1201 atcacataaa aaagctcatg attattcaaa aatatatcaa atattatcaa agactaaaga
     1261 gttaaaattt gataaagagg attctaagga tgttttagga ttgctagttc ctagattaaa
     1321 atctatatct caagaagttc atttagatga taacataaaa aataatataa caaaagattt
     1381 taaatctgag ttctactttg atatgattga tggcaacata tgttgtgatg taaagtatat
     1441 atatgatgat gaagataaaa aatttgtgct ccccaacata caaaaggaag ctactattga
     1501 aaataaactt acttcttcac aatttacaaa ggaaaataat cattatgtgt ttaaaggaac
     1561 tgaccatgac ctatttacat ttttagattt acaattagaa tctctaaagg aatttggaga
     1621 tatatattat tctgagaagt ttaaattgaa aaaaatatat aacgcttcat caattcaagc
     1681 ttcaatcaat cagactaacc agaattacct agaatttaat tttaatatat ctgatataaa
     1741 tccaaaagag tacaaggata ttttgaaagc ttttcaagaa aaacgtactt tttataaact
     1801 taaagatgga aactttatag atttatcaga aagagaaaca aaagattttt ttgaattagt
     1861 tgaaaatcta gatataatgg ataaatcaaa aaataataaa attcataaaa ataaagctct
     1921 atatataaat gatgtaatac gtagtaaaaa tttaaagttt atagatggta aaaaagaact
     1981 agacagtata tgtgaaaaat ttagaaattt tgatagcata aatttagaaa ttcccgcaaa
     2041 tttaaatgca aaccttcgtg actatcaaat aaatggcctc aattggttta aagttttaga
     2101 ttattataaa tttggtggta tattagctga tgaaatgggt cttggtaaaa caatacagac
     2161 tattgcattt ttattatcat tatctaataa aaaaagtctt attgttacac cgacatcact
     2221 catttataat tggaaaaatg aatttgaaaa gtttgctcca gatataaaag ttttattgat
     2281 acatggaaat aaaagagata gagaaaaatg ttttatggaa ttagaaaatt ttgatgtaat
     2341 acttacaaca tatggtactc ttagaaatga tttagaaaaa tatagtgaaa taaagtttga
     2401 ttattgtata ttagacgaag ctcaaaatat aaaaaatcca gtagctttag taactgagtc
     2461 tgtaaaaagt ataaatgcag aaaataaatt tgcactcact ggtacaccta tggaaaataa
     2521 tctactagaa ttatggtcta tatttgattt tataatgcct ggctatctat atagtaaagc
     2581 aaagtttcag gaattgttta taaataaaga agataatatt aaaaacctga aaaaattgat
     2641 aaaacctttt attcttagaa gaagtaaaaa acaagttatg aaagaacttc cagataagat
     2701 tgaaaaaaac ttttttgttg aattgaataa agagcagaaa aagatatata gtgtatattc
     2761 aaaagatata caagataaaa tgaaagataa aaatttaaag aaagataaaa tagttatatt
     2821 ttcttattta actaaactaa gacaactttg tttagaccca agtatagtag taaaagatta
     2881 caataaaaaa agttcaaaaa ttgaaacatg tttagaaata cttagggata gtataaacga
     2941 aaaccacaaa atattattgt tttcacaatt tacttctgtg cttaagaaca taagtaagga
     3001 acttgataag tataaaatta aataccatta tatagatggt aaaactaatg ccaaagaaag
     3061 acttgaactt gtagatgagt tcaataatag tatggataaa aaagtttttt taatatcttt
     3121 aaaagcaggc ggaactggtt taaatcttac atctgctgac atggtaattc actttgaccc
     3181 atggtggaat ccatcagtag aaaatcaagc tagtgataga gctcatagat ttggtcaaaa
     3241 aaattcagta caagttataa aattgattgc taaagggact atagaagaaa aaataataaa
     3301 attacaagaa agtaaaaaag agcttataaa tcaatttata aatggagaac tttctaatga
     3361 aggtgtatta aaaagtctat ctgatgagga gataataaac ttatttaact aaattattta
     3421 atcctacagc ttaactatat aaatttgttc taacatttat atagttaagc taaaatatct
     3481 gaataaataa aatttaatat tgttatttaa tcccaacttt acaatctaat gatatctctt
     3541 tctatacata ttgcatatac aaatgtaata acttgactat tagaatattt tgttttaaca
     3601 atactatttc atcataataa tgaagtatat gtacactcac ttttgtaagt tttgcaatcc
     3661 attttacagt tttcattatt gtaaattttg gttaaattat tcctctaaaa atttctttgc
     3721 tacatttgaa aaatctaatc cattcgataa aattgcagga tgaccacctt tatcaaacaa
     3781 atacatttta ccatttttaa tcttttcaag aagtaatgaa aaagtatttt caaaaaaatc
     3841 actagatatt agagatacaa actcatcttc tctacttcct gttaaaagca cctctggttg
     3901 catagtttct agaggcttat gaaaaaactt tcctatagtt ttataatgtt caaaaatagc
     3961 ttctgtatca ttatctacaa ctttttccca gttttctcct tgattataaa tataaaaagc
     4021 ttttgcacca tcatcttgct tagatgcttc acgctctatt ttcacatttt gtacaaatga
     4081 ctctagagga acttctcctt caaaactatc tgcaattacc ttattcacta aatcaggtct
     4141 ctcaagtgca acatttaatg caacaagagc tcctccacta ctaccaatta tgtttacttt
     4201 tttatagttc attgcttcta aaaaacatat cacttgcata gcctcatcaa accataagtc
     4261 agcagaaaat ttatcgacca tttgagattt tccatgacct acaaaatcaa ttaatattac
     4321 tttatattca tctttataaa aatcgattat atcattaaac atcttggaag aggctgtatt
     4381 tccatgtaaa aaaagtaatg gtgtaccatc cccaatttca ttatagtagc actgtttgtc
     4441 gttatagtta aaatatgcca tatattttcc ccctttaata tccctatagg tatatattta
     4501 ttacttatat ttaaaatgac tattccctta gccacttaaa aatagtataa cttagaatgt
     4561 agataaaatc aacattcctt gctaatttat ctattgtttg tctaatttat tataatttaa
     4621 cttctgtaaa atttcttttt tgtacgaaaa tattccttcc atttacaaca atcattcaaa
     4681 tgaagtataa catgacgagt aggaggcata agcaaaattc cagcaatatc tttattcccc
     4741 caaaagtcca acaaccaaat agaatcttca tgctttatta ctcctccagt caccaaaatc
     4801 ctttctaagt caattggaga gacctttcgt ttcatatctt cagctttcaa atccttaaca
     4861 acttctattg tgttttttgc aacttcattt cgataacaaa gcaattcatc aatattgact
     4921 aaattatcgt atatctcttt tcactttaac catttttttc tttataggta tctccttata
     4981 tttttttaat atcaaatctc ccttataatt taatatatct acatatgaac ataaatcttg
     5041 aacttcaatt acacctatat catcattagt tatacctttt atattactaa atgcaccaac
     5101 tatatctaaa actcttattt tcttcttctt accagcattt aaatataatt taacaacttc
     5161 actttctata tttagtttta tatctttact tttgtaagaa tttttatcaa ctttttttct
     5221 ctttgatact ttttttagga ttccttttga atattcttca aacaaaactt tgccatgtgt
     5281 aattctactt tgttctatat ctgttaattc atttatttta tatcctatat atgtttctat
     5341 attctctata tatttttcat ccttttcagt tactatagta attgccttcc cactatttcc
     5401 ttttctccca gttctaccta ttctatgtat atagttttct ttatcttgtg gtacatcata
     5461 atttattact aaagaaatat catcaatatg tattcctcta gacgctacat cactactaac
     5521 taatatatta aatttttggt ttttaaaatc cttaattaca aaaattcttc tttcttgtga
     5581 taaatctgca tgtaactctc ttattaaaaa accctcttta ctcatcttat tatataattt
     5641 agatactttc tctttggtat tacaaaatat tatcacactc tttggatttt cgctgtatat
     5701 taattctttt aaaaggatgt acttctctct tccatttgcc ttgattattt tgtcatctat
     5761 ttgtcttgtt ttttgattag tatcgctctc attttcttct atatttataa cactgtaatc
     5821 tagcatatat ttttcacata tatattttat ctcttcatct attgtagctg aaaaaagatt
     5881 tactattttc tccttaggta aatttaataa tattttttcc atttgttcaa caaaaccttt
     5941 attaaacatt ttatctgcct catctattac taaatacttt acattttcca acttaataga
     6001 acctctattt atatggtcaa gtattctgcc tggagtagct acaacaatat gaaccctttg
     6061 tttcaattca gctatttggt cttttataga ttgtttgcca aatatagcac tacatctcac
     6121 cttctttagt ctccctatat ctgatatctc atcttttact tgcaaggcta attctcttgt
     6181 tggaaccact ataagagctt gaatattatt gtaatctaca tttatattct cgcataaagg
     6241 tattgcaaaa cttgctgtct ttccacttcc tgtttttgac ctaactacta agttttgacc
     6301 ttttaataat tttggaataa cttctctttg tactctagaa ggtatattat atcctaaact
     6361 cttcaatgac ttaagtatct tttcatttaa cttaaatttt tcaaatgtat atttcatata
     6421 ttaccacctt attatattta tcttatctat atatttttct acattatatt attataat
//
LOCUS       DAEQAF010000143         6461 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.147, whole genome shotgun sequence.
ACCESSION   DAEQAF010000143 DAEQAF010000000
VERSION     DAEQAF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6461
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.147"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..664
                     /locus_tag="KRN00_003419"
     CDS             <1..664
                     /locus_tag="KRN00_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829243.1"
                     /translation="KSYKLLNRFNLGLQNGEQQNINEIKFSIGSKLYLEIVNNKSKNG
                     YIEGHDSYSNFIIYDIEDNTFNISNKFMDNLNKEKNANPKEIGLLSKTKLDYMVKNNK
                     LNLIVTDMSNSITNLVYDINSNEIKLEDYEILDLKVDYNEASSGVRKVKLLDDKIYSI
                     SGIKNSISGELKGFKGIVDVVGTKPVKFQVFDMKLKKNIYEAELINGDISLQEKLFFV
                     TN"
     gene            1030..2211
                     /locus_tag="KRN00_003420"
     CDS             1030..2211
                     /locus_tag="KRN00_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1829244.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(2353..3270)
                     /locus_tag="KRN00_003421"
     CDS             complement(2353..3270)
                     /locus_tag="KRN00_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829245.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            3523..4317
                     /locus_tag="KRN00_003422"
     CDS             3523..4317
                     /locus_tag="KRN00_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1829246.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            4318..6378
                     /locus_tag="KRN00_003423"
     CDS             4318..6378
                     /locus_tag="KRN00_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1829247.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT         2507 a          696 c         1052 g         2206 t
ORIGIN      
        1 taagtcttat aaattattaa atagatttaa tttaggatta cagaatggag aacaacaaaa
       61 tatcaatgaa attaaatttt ctattggaag taaattatac ttagaaatag taaataataa
      121 aagtaaaaat ggatatattg aaggacatga tagttactct aactttatta tatatgatat
      181 agaagataac acttttaata taagtaataa atttatggat aatctaaaca aagaaaagaa
      241 tgcaaatcca aaggagattg gcttattaag taaaactaag ctagattata tggtaaaaaa
      301 caataaattg aatcttatag ttacggatat gagtaattcc ataactaatc ttgtttatga
      361 tattaattct aatgagatta aattagaaga ttatgagata cttgatttaa aagtagatta
      421 taatgaagca tcatctggag ttaggaaagt taagctactg gatgataaga tatattctat
      481 ttcaggtatt aagaacagta tatcaggaga attaaaagga tttaaaggga ttgttgatgt
      541 agtcggaact aagccagtaa aatttcaagt atttgatatg aaacttaaaa agaatattta
      601 tgaagctgag ctaataaatg gagatataag tttacaagaa aagttatttt ttgttacaaa
      661 ttaagtgtta gaattaattt tagaacttta aacttttata tgtatcacag ataagtataa
      721 gtaagggagt gtctcaaaat aaacttttta gctcatgaga cacttttttt atatgaaatc
      781 aaatatattt tcattgttta gatttatttt gatagtgaaa aaaagattat ctttatttta
      841 agaaagacat ttatttataa ttatatacaa aaatattttt taatgttttt gtgtataatt
      901 ataacaattt aatttatatt aatgcactta aatttgaaat agaatgctta tagtggtaaa
      961 attaattatt agaatattag aaataataaa taaataatac attgtactta aaagggggag
     1021 aaatttaaga tgaacaaaaa atatattaaa gcagggaatt taattgatgg aaccggaaat
     1081 agtattatgc aaaataaggg tataattatt gatggagata ctatagttga aattgaagat
     1141 ataagagatg atttaaatgg atatgatgtg tacgattact tagataaaac tgttatgcca
     1201 ggcattatga attgtcatgt tcacttgaca atggagccag ttggaaatcc aaagatatat
     1261 tatgataatg tatcagatgt agagcttgta gtaaatacga taaaacaact tgatgcttat
     1321 ttggattcag gagtaacata tattagaagc ttaggttgtc ccaaatatgt ggatgtacaa
     1381 cttaaaaatc ttatagacaa agggtctata gatggtcctg gtatagttac ttcaggtcca
     1441 gttatatgta tgacaggagg gcatggatat tattttggta ttgaaagtga tggagtggat
     1501 gaatgtagaa aatcagccag aacagtttta aaaaatggag tagattgtgt aaagataatg
     1561 gcaactggag gtgtaacaac tgatggagtt gagccagggt caccacaatt aactttggag
     1621 gaaatgaagg ctgctgtaga tgaagctata aaagcaggta aaataactgc cacacatgca
     1681 caaggaagaa ctggtataaa aaatgcagtg cttgcaggaa ttacttctat agaacatggt
     1741 gtttatttag atgatgaaat aattgatttg atgcttgaaa gaggaactta cttagttcca
     1801 actgtggctg caccatattt tattctaaat gcaggaaaag aaagtggaat aactgaagct
     1861 actcttagaa agtgtgagat tgttgccatt ccacataaag agtcattcct aaaagcatat
     1921 aaaaaaggaa ttaaaattgc agttggttct gatgcaggaa cttcttataa tgaacatgga
     1981 aaaacatatt atgaaatgaa actaatgtca gattatggta tggataatat ggatataata
     2041 gttgctgcta caaaaacagc atctgaactt ttaagaattg ataaaaatta tggaactcta
     2101 gaaaaaggaa agaaagcaga tgttatagtt gtaaatggaa atccagtaga gaatatagac
     2161 gtacttgcag atgtgttagc agtatttaaa cttggtaaaa aagttagata aatagtataa
     2221 aaataaaaaa gagtgtctaa agaaattttt aaataattat agacactctt ttttattagt
     2281 aataattaaa tcttttatac tttagaaaat agattctatt ttatatttag atataactct
     2341 ttaaaatcat tcttatgcaa tataatctat agaatctaca catacaaagt atattcttga
     2401 atcattagaa tttccaagta ctataacatc atttttctta cctagaactt caacaccagt
     2461 tagaaccaaa ctaccagcta ctacagtaac ttgattattt atatttgaca tataaagatt
     2521 atctaggata cctttattac aacagcaatc atcacaatcg cagttgcaat tacattcttt
     2581 gtaatgtttt ttatcaagat agtaacctaa agatgctatg aaatcttcat aatctgcagg
     2641 tgtaatatca aatgcaacag ctttaagatt acacaatgat gctaaatcta cgtttgctaa
     2701 tggagtagat gcagcaagta taaaatcaat tatagcagca agtattgcat ctaatatagc
     2761 cccaaggtct atcgtaggag gaataactgc atcaataagt gcaattaatt cagctactcc
     2821 tggtatagtt cctatagtat taattaatcc ctcaagagtt aaagggactg gaataggata
     2881 agatactcta ccagctatat ctattaaatc acagttacaa gcagaaaatc tttcaaaagt
     2941 accatcaagt ccagataaat tatcttttgg aggagctgaa agatctatac ctaccaaatt
     3001 agcacctact ataaagaaat ctgagataaa agcaaattga ttaaagttta caaaaggtct
     3061 tagagcatca tatcttagaa gttctaaggc ctctctcata ctttttttac aacaacattg
     3121 ttttatttta ggttctttat atttatttgg ataattatag tatctatcag ctacttgata
     3181 attttcatag tatctttcat ttgtatttgg ataatcttcc tcatattctt gtgtaaatct
     3241 aaagtcctct ctacatttat tattttccac gaaatacact ccttttatat tttaatttaa
     3301 atgtatagat aattaagctt atctatatag taatattata tttataatgt aaaaaaatgt
     3361 tacaaaagat attataaacg aataaaaaat aataatttgt cagataaact tgtaaatttt
     3421 tatgaataat ccattctaaa acaaaaaact gtgtataaaa aaggtttata tgttatattt
     3481 atataaatat aacatatgaa cgagaaagga gtggtttgat aaatgattga ggtagataaa
     3541 ttgtgtaagt cttttacaag ggttgtaaaa gatgataaga ataaaagttc aataagaaag
     3601 ctaaagaaag taaaaactaa aaaagaagaa ttttttgctg taaataatgt ttcatttaaa
     3661 gttatggaag gtgaaattgt tggaatatta ggtccaaatg gtgcaggaaa gactacatta
     3721 cttagaatgt taggtggcat attaacacca acatcaggaa gtataaatat ttctggatat
     3781 gattattcaa tagatagaaa ttcagcaaaa aaagaaatag gttatctctc tggaaataca
     3841 aaactatatg gaaggctttc tccgagagaa cttctaacaa cttttgcaag tctatatgag
     3901 atgtcaaaag aagatataga agaatcaatt gaaaatattg taaaaataat ggatatgagt
     3961 gaatttatag ataatagaat tgaaaatcta tcaactggtc agactcaaag aacatctata
     4021 gctcgttgtt taatacattc tccaaaagta tatatttttg atgagccaac actaggtctg
     4081 gatgttttaa gtagtgcatc tattatagat tttatgaaga atgaaaaact aaggggaaaa
     4141 actgttcttt actcaactca ttatatggaa gaagcagaaa ctttatgtga caagattttt
     4201 atgattcaca atgggaaaat aattgcatca ggaacaccac agagtttaaa agaggaatct
     4261 ggagtaaata atttgagaga tgtattcata aaacttgcca gaaaggagga catttaaatg
     4321 agaagtaaga ttgtaaaata catatttaaa aaagaaatgc tagacatatt gagagataaa
     4381 aagactttat ttatgatgat tgttgtgcca cttcttttat atcctttact tatgttatta
     4441 atgattcaag taatgaatat gtctgcaagt agtatgaata gtaaggacat taatatagct
     4501 tttaataata aacctaataa ggttttagta tccatgattg aagatgataa tttagaaaaa
     4561 gatactaaaa atacttcaaa tgataaaggc aaaataagag tgttagatgt agataactat
     4621 aaaaagtcat tagaagaaaa taaaattgat gcttatataa agatggaaga aaaaaaatca
     4681 tctataaatt atcaaatata tataaattct tctcaagaaa attcttctaa tgcactaaaa
     4741 agaattgaaa ctgttttgga taaatataaa agatttacca tagaaaaaac tttatctgaa
     4801 aaaggattag atgtacaagc tactttagaa ccaataacat atagcactgt agatgttgca
     4861 aagacggaag aagtggcagg atacttttta ggtcagatac ttccatttat attaataata
     4921 ggagttttac taggttcaat atatccagca atagatgtta tggctggaga aaaggaaaga
     4981 ggtacattag aaacattatt tacactgcca atatcaaact tagaactggt tatgggaaaa
     5041 tatatggcag tttctcttag tgcaatagta acagcaattt taaacatttt atctatggga
     5101 ctgactatgg catttatttt agttagtgga ggtattagta gccaatttgg ctttggaaac
     5161 tttaattatg gagacttagt cttaccaatt ataactactt taatttgcat atgtcttttt
     5221 tcaatggtag tttcagcaat aagtatgtgt gtatgttcat tagcaaaaag ttttaaagat
     5281 gctcaaaact acataacacc tcttatgtta attattatga taccatcata tgtttctatg
     5341 ataccaaata tagtattaga tagagtgaca gctgtaatac ctgtagtaaa tatatcttta
     5401 cttataaaaa gtgtattatc ttttaaaagc gatttaaatt taatagcctt agttttagca
     5461 tcaaatgtag cctttgttat attggcaatc atactactgt ctaagatgtt caattctgag
     5521 gaaatacttt ttggtaatag taagagtttt tctttcttag agaaaagaag taatataaaa
     5581 aaagggtcta taccaactgt aagtgatggt gttattttat atgcagtagg attagttcta
     5641 ttgatttatg ttggttcttt agttcaaatt aaatttggta tggcaggtat tataatgaca
     5701 caattcatga taatttcttt accattatta tttgcatact atattaaagc tgattttaaa
     5761 gaggtattta gcttgacagt tcctaaatta aagcatgtgt ttgggagcat tgttctttgg
     5821 attggtggat acatacttat tatgattata acacagctaa ttttattctt atttcctcaa
     5881 aatatggaag ttgctgaaag tttaaataag gctcttttta tcaaagatag tgttttactg
     5941 aatttactag caatagcttt attaccagct atatgtgaag aaatgttttt taggggattt
     6001 atattttctt catttagtaa atcaaaagat aaaaataagt ctatcaagct agctataata
     6061 tgcagtgggg tactatttgg tattatgcat atggatttta ttagaataat tccaacatca
     6121 atattaggta ttatatttgc atatagtgtg tataaatctg gttcaatatt tgtatcaatg
     6181 ttattgcatt ttttaaataa tagtgtagca gttgtgttaa atcattatac aactggaaat
     6241 ataaccaact tatataaatt tgttgaagtt gatttttcga acttaaatgt acttaaattt
     6301 gccttaattc ttctaataag tcttatatta attatgttag gattaagagt tttagataga
     6361 aagtctttaa gaaattaagt ataaagttat tatatagatt aaaatattaa taagcactaa
     6421 agtatatgga tatatcttgt atataaaaat actttagtgc t
//
LOCUS       DAEQAF010000144         6260 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.148, whole genome shotgun sequence.
ACCESSION   DAEQAF010000144 DAEQAF010000000
VERSION     DAEQAF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6260
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.148"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            204..1226
                     /locus_tag="KRN00_003424"
     CDS             204..1226
                     /locus_tag="KRN00_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1829248.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            1286..2293
                     /gene="gap"
                     /locus_tag="KRN00_003425"
     CDS             1286..2293
                     /gene="gap"
                     /locus_tag="KRN00_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBH1829249.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            2515..3717
                     /locus_tag="KRN00_003426"
     CDS             2515..3717
                     /locus_tag="KRN00_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBH1829250.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            3743..4486
                     /locus_tag="KRN00_003427"
     CDS             3743..4486
                     /locus_tag="KRN00_003427"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBH1829251.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            4495..6027
                     /locus_tag="KRN00_003428"
     CDS             4495..6027
                     /locus_tag="KRN00_003428"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBH1829252.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVVSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGKLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTVLDMMKLEKPEEMTGHSLI
                     SK"
BASE COUNT         2508 a          727 c         1252 g         1773 t
ORIGIN      
        1 atataaaaag ccttatataa aaagaaaaaa tactgtgatt tgaaaatggt ggagaaatat
       61 tttataaaat aaaaaaataa aaaagttttt gaaaaactat tgaaatctat acgcaaatcc
      121 tataaaataa aaatatcttg tgggacttaa ataaacacta gggacaaaaa aagtcccgaa
      181 aggaaagcaa taaggagtat gttatgaaga acttattaga aattcaaaag aaattgattc
      241 cacaggcaat tgaacttatg gaaagaagat actctatttt aagacaaata tctttaagtg
      301 aaccaatagg taggagaaca ttatcaaatg tattagagat tagtgaaaga ataatcaggt
      361 cagaaactga gtttttaaaa gaacaaggac ttatagacgt agctgtatct gggatgacta
      421 tcactaaaga aggttctgat ttgttagata aacttaagga catcatgagt gacatcatgg
      481 gattgtctaa gttacaagat agagtcagag aaaagcttgg aataaaaagg gtaatattag
      541 ttcctggaag ctgtgatgaa aatggaagtt tactaaaaga tgtaactaga tatggatgcg
      601 aatatttctt aggcatttta aaagatggag atatcgtttc aataacagga ggaagcacta
      661 tgttggagtt ttcaaacgtt attaaaactg ataagagata tccaaactct acaatagttc
      721 cagctagagg aagtatggga actgatgtag agatgcaatc taacaatata gttgcttcaa
      781 taagtaagaa attacattct aattgcaaac ttttacatat accagatgag ttggatgaaa
      841 gtgcaatgaa aactcttagc caagtgccag agattaagac aactttggag tatattaaaa
      901 gaacagacat tttagttttt agtataggta gagcagatgt catggcaaag agaagaaaac
      961 ttccagaaga caaggttgat gagatattat ctaaaaatgc agttggagaa gcatttggat
     1021 attatttcaa caaagatgga gaaatagttt acaaactgaa cactgttgga attgatttag
     1081 aaacagttaa acaagtaaaa gaaactattg caatctttgc agggactgaa aaagtagaag
     1141 ccttattagc tatatcaaat atgcataaaa acatggttct tgtaacagat gaagaaagtg
     1201 cttataagat attgtcatta ttataaaagt caagacctag cacagagcta gaaaacatac
     1261 atttacttta taggaggtag cgaaaatggt taaagtagct ataaatggat ttggaagaat
     1321 aggaagatta gcattaagaa aaatgatgga gcaacaagat aagttcgaag ttgttgcaat
     1381 aaacgactta acagacgcta aaatgttagc tcatttattt aaatatgata cagctcaagg
     1441 aagatttaac ggagaaatag aagttaaaga aggtgctttt gtagtaaacg gaaaagaaat
     1501 aaaagtaaca gcagaaagaa atcctgctga cctaccatgg gctgaattag gagtagatat
     1561 agtattagaa tgtacaggat tctttacatc taaagataaa gctgaagctc atatacaagc
     1621 aggggctaag aaagttgtta tatctgcacc agctactgga gatttaaaaa caatagtatt
     1681 caacacaaac agtgacatat tagatggttc tgaaacagtt atatcaggag cttcttgtac
     1741 tactaactgt ttagctccaa tggctaaagt attaaatgat aaatacggta tagaaaaagg
     1801 attaatgact actatacatg catacactaa tgaccaaaat actttagatg gtcctcatcc
     1861 aaaaggtgat ttaagaagag ctagagctgc tgctggaaac atagttccaa acactacagg
     1921 agctgcaaaa gcaataggct tagtaatacc ttcattaaaa ggaaaattag atggggcagc
     1981 acaaagagta ccagttgtaa ctggttcaat aactgaatta gtttgtacat taggaaaaaa
     2041 tgttacagtt gaagaaataa atgcagctat gaaagaagct tcaaacgaat ctttcggata
     2101 tactgaagaa atgttagtat cttctgacat aatcggaata agctacggtt cattatttga
     2161 cgctactcaa acaaaagtta tggaagtaga tggaaaacaa ttagttaaag ttgtttcttg
     2221 gtatgataat gaaatgtctt atacttctca attaataaga actttaggat actttgcaca
     2281 attagcaaaa tagtcagttt tgagaaaata gaaaagtaga ttgacaaagt ccgagtttgt
     2341 agtttaatac tacggactca ggactttttt taagaaaaaa tatataaaat acacctaaat
     2401 aatgttacat actatatata aaaatatgat aatatgatat atttaatagg gtaaaagtat
     2461 gtactatatt atacttggca ataaaaaatt actttattaa aaggagagat atttatgtca
     2521 atgcttaaca aaaaaactat agaagatatt gatgtgtgcg gaaaaaaagt attagtaaga
     2581 tgtgacttta atgtgccatt acaagatggt gtaattactg atgaaaatag attgaacgga
     2641 gctttaccaa ctattcaata tttaatttct aaaggggcaa aagttatatt atgctctcac
     2701 ttaggaaagc caaaaggaga agctaaacca gaattatctt tagcaccagt agcaaagaga
     2761 ttatctgaga tgttaggaaa agaagttgta tttgcagcag acgataatgt tgtaggagaa
     2821 aatgcaaaga aagcaactga aaaaatggaa aacggagatg tagtattatt agaaaatact
     2881 agatatagaa aagaagaaac taaaaacgaa gagaatttct ctaaagaact agcatcactt
     2941 gctgaaatat ttgtaaatga tgcatttgga actgctcata gagcacattg ctcaacagtt
     3001 ggtgcaggcg agtttttaca agagagagtt tgtggatact taattcaaaa agaattaaaa
     3061 ttcttaggag aagctgttgc aaaccctgta agaccattta cagctatact tggaggagct
     3121 aaagtttctg ataaattagc tgttataaac gaattattag aaaaagttga taatctaata
     3181 ataggtggag gaatggctta tacattctta aaagctcagg gttatgaagt aggaacttct
     3241 ttacttgaaa tagataaagt tgaatatgct aaagaaatga tggaaaaagc taagaataag
     3301 ggtgttaact tattattacc agtagacgtt gttatggcag accactttgc accagatgct
     3361 actccaatag taacagaaga tgctaatgta aaagaagatt acatgggact agatatggga
     3421 cctaagacta tagcaaactt tgtaaaaact ataaaagaat caaaaactgt agtatggaat
     3481 gggccaatgg gagtatttga atttgaaaac tttgcaaatg gtacattatc agtagctaga
     3541 gctatggcag agttgactga tgcaactact gtaattggcg gtggagatag tgcagcagca
     3601 gttaatcaat taggatttgg tgacaagatg actcacgtat caacaggtgg aggagcatca
     3661 ctagaatttt tagaaggtaa agaattacca ggtattgcag cattagataa taaataaact
     3721 aatatataga ggagattgta aaatgagaaa acctataatt gcaggaaact ggaaaatgca
     3781 taaaacaata aaagaagctt tagaatttgt aaatgaagtt aaagataaag taaattctga
     3841 taaagtagaa gctgttatat gtgcaccatt tactttatta aaggatttaa aagaagctac
     3901 taagggtaca aatataaaga taggtgctca aaatatgcac tttgaagaaa aaggagcatt
     3961 tacaggagaa gtttcacctc ttatgttaaa agaaatagat atggactatg ttgtaatagg
     4021 acattcagaa agaagacaat acttcaatga aactgatgaa actgtaaaca agaaagtttt
     4081 aaaagcatta gaagtaggaa tagacccaat attatgtgtt ggagaaactt tagaacaaag
     4141 agaagctgga aaaactaaag atgtttgtaa agttcaagtt gaaaaagctt tagaaaatgt
     4201 tcttaaagat gatttagcaa aagtagttgt tgcatatgag ccaatctggg ctattggaac
     4261 tggtaaaact gcaactgctg aagatgctaa tgacgttata tcttatataa gagaagttat
     4321 aaaaggatta tatggagaat tagctaatga agttagaata caatacggtg gaagtgttaa
     4381 accttcaaat gtagccgaaa taatgggtca aagtgatata gatggagctt tagtaggtgg
     4441 agctagttta gctagtaatg attacctaga ccttgttaat ttctaaggag tgaaatgatg
     4501 aaaaaaccag ttgctttaat tattatggac gggtttggat acaataagga tgttaaggga
     4561 aatgcaattg ctgagtccaa aactcctaat ttagatagaa taaaaaaaga gtatccaaac
     4621 acattgataa atgctagtgg tcttgatgtt ggtctacctg atggtcaaat gggaaattca
     4681 gaagttggac acactaacat aggtgcaggt agaatagtat atcaagattt aactagaata
     4741 acgaaatcta taaaagatgg tgactttttt actaataaag ttttatgtga agcaatggat
     4801 aatgcaaaag aaaattctct tcatgtaatg ggacttttgt ctgatggagg agtacattca
     4861 catatagacc atcttaaggc tataatcaaa atggcaaaag ataaaggcgt acaaaaggtg
     4921 tatgttcacg catttactga tggtagagat actgaccctc aaagtgcatt agaatatgcc
     4981 aaagaagtac aagctagtat ggatgaaatt ggagtaggtg aatttgctac agtttctggt
     5041 agatactacg ctatggatag agataagaga tgggaaagag tagaacttgc atacaatgcc
     5101 atggttagag gtattggtga aaaagcaaat tctattgagg aagctattca aaactcttat
     5161 gatgatggaa aaaatgatga gtttataatg ccaacagtta ttatgaaaga tgataaacca
     5221 gttgtaagta taaaggaaaa tgattcaatt atattcttca actttagacc agatagagct
     5281 agacaaataa ctagagcttt agtttgtgaa gagtttgatg gatttaaaag agaagatatt
     5341 aaaaacttct ttgtatgctt aacagagtac gatataacta tagagaatgt gcatatagca
     5401 tttggacctc aatctttagc caacactcta ggtgagtatc tagctaaaaa tggaaaaact
     5461 caacttagag ctgctgaaac tgaaaagtat gcacatgtaa ctttcttctt caatggtgga
     5521 gtagaagagc caaataaagg tgaagaaaga ctattgatac cttctccaaa ggttgcaact
     5581 tatgatttaa aaccagaaat gtcagcatat gaattgacag ataaagcttt agataaatta
     5641 ggagaagata agtttgactt tatagtatta aactttgcaa atcctgatat ggtaggtcat
     5701 acaggaagta tagaagcggc tataaaggct gttgaaactg tagatacttg tgtaggaaaa
     5761 ttgatagata aaatagtaga gttaggtgga agtgcaataa taactgctga ccacggaaat
     5821 gctgaatata tgttagaccc agaaacagga aaaactgtaa cagctcactc tattaatcca
     5881 gtaccattta ttgtagttgg tcaagaatat gaaagtgcaa aattattgga tggaggaaga
     5941 ttatctgata tagcaccgac tgttttagat atgatgaagt tagaaaagcc agaagaaatg
     6001 actggtcatt cacttatttc aaaatagtcg attttgataa gtagagaata atatataaac
     6061 tacaatataa atttaaaaat aatgcagttt aggtttattt tgtaaagttt agactttatg
     6121 acataagatt taaattttgt aagttctgga tattgtaagg tgtagatgaa gatatatttt
     6181 ataaaattta caagatagac aatttataaa ataaaaaatt acaatataga taataatgta
     6241 aataatgata taaataataa
//
LOCUS       DAEQAF010000145         6169 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.149, whole genome shotgun sequence.
ACCESSION   DAEQAF010000145 DAEQAF010000000
VERSION     DAEQAF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6169)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6169)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6169
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.149"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(1213..2619)
                     /locus_tag="KRN00_003429"
     CDS             complement(1213..2619)
                     /locus_tag="KRN00_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBH1829253.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKEILHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2664..3371)
                     /locus_tag="KRN00_003430"
     CDS             complement(2664..3371)
                     /locus_tag="KRN00_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1829254.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     RVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKDGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            3542..4456
                     /locus_tag="KRN00_003431"
     CDS             3542..4456
                     /locus_tag="KRN00_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1829255.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            4456..5217
                     /locus_tag="KRN00_003432"
     CDS             4456..5217
                     /locus_tag="KRN00_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829256.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFVAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSISVLMQVLSIMLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            5229..5966
                     /locus_tag="KRN00_003433"
     CDS             5229..5966
                     /locus_tag="KRN00_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829257.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEVANRNFRKNDVIS"
BASE COUNT         2131 a          974 c          718 g         2346 t
ORIGIN      
        1 tttactacaa cttattactg aacttcctac ttcctaaact ttttatttac tacaacttat
       61 tactgaactt ctcacttact aaacttttta tttactataa cttattactg aacttctcac
      121 ttactaaatt tcttacttac tataaattat aactaaactt ctcacttact aaatttctta
      181 cttactataa attattacta aatttcctac tttctaaatt tcttacttgc tataaattat
      241 tactaaactt cctactccct aaatttctta cttgctacaa attattacta aacttcctac
      301 ttcctaaatt tcttacttac tactacttat aactaaactt cccacttcct aaatttctta
      361 cttactacca cttataacta aacttcccac ttcctaaatt tcttacttac taccacttat
      421 cactaaactt cctactttct aaatttcttg cttactacca cttataacta aactttttac
      481 ttcttaaatt tcttacttct taagaataat tttaatttta agattatagt ttttgccttg
      541 tttaattgaa acattctata taattatatc cttctatttt agagtttttt tatttatata
      601 ttacaaagtt taaatttttt cattaattat attataaatt ttccatatat ttcaacataa
      661 atacatatat atatatgtta tctctaaaaa tactacacaa aaactctact ttagtagaac
      721 tcaatggcgc aaaatacttc aatttaaaac atttatcgta ctttaaataa ataactataa
      781 taaaatatac ttacaatagt tacatagaag ctattataac tacacagaac aacgtataat
      841 taaaactttt ttaggatgtc attatatttt ttcttaaaat taaaaaacac tataccataa
      901 ttctatttta gtagaatttt tttgtcaata ataaaattaa atattaacta aaaaataaaa
      961 aaaatggaat tatctaaaga atttaataac cttacaataa ttccaaaata ttatttctat
     1021 gaaaattttg ataccataag taactcagcc ataagcgcat aaagcacaag ttactcttta
     1081 ctttaataaa acttgacaag aaaagaattt attcttattc tactctaata gagttaattt
     1141 gtcaataaag aataaaatta ttttcaaaat attttcattc ttcattctta tctgttatta
     1201 ttttataaaa tatcacttaa ttagaggtaa ttttagtatt gtttttagtc cctgactatc
     1261 aatgctcgta atatctaatt tacctctatg tgcattaata atgccagata ctatcaaaat
     1321 acctagacca tgattttgac ctttggcata tgcctcactt agtccatttt ggctctttaa
     1381 taaactatta attctttctt gactcatacc ttttccatca tcttcaacaa ttatatagca
     1441 aaaatctaaa tcagacttag aggtaaccct tatattacat ccttgttggt tatgagttat
     1501 actattttgt attaaattac taatagccct ttttaataat tttttatctg catctataat
     1561 aatatcttca tttagtatat caagttcaac gtaaaagtca ttatccaaat tattatttat
     1621 aaactcagaa ataagctctc tcaaaaacgc agaaactcta atcttatcac aattcaatgc
     1681 ttgcatatta tattcaagtt tagacactaa atttaggtca tttactaatt ctctgatttt
     1741 aatcccttga ttgcatataa tagacacttg ctcttgttct ctatttgaaa ggctactgct
     1801 ttcttcaagt tctccagcat atccaattat cattgaaagt ggagttctta tatcatgaga
     1861 tattcctgca atccagttag acctagcttc ctctttcttc ctaagttttt catctttcat
     1921 ttgcaactct ttagatacag tattaataga ttttgaaata tcacttagta ttcctttttc
     1981 ttgtaaaagt actggttctc cttttgacat aagctttatg ccagtaataa ttggttttat
     2041 agatttcacc atttttaaac ctatgaatag agctattaaa aaagtaacta ttgcattaac
     2101 cagaaacata cctattatta acataggaaa ttgttctatt tccttaaccg tataagtaag
     2161 gttaaactta gtgtacttgt cttttggata acctgttact aatattccat ttggatgttc
     2221 ccatacatac acaggatagt cctttaaaaa gaaccttgaa aactttgcta catctgtcaa
     2281 agtataatga cttggaattt cttttggtaa atcaaatccc catattctat ctccattgtt
     2341 atcaattaac attgcccaaa ctttattttt atgtagtatt tccttactag aatcatctaa
     2401 aataaacttt ccatctttta aaaccaaatt atcttcaatc ataatcaagt ttgattttat
     2461 ttctctgcta tcacttgtat ctaaattatc agagtattta gatacaaata gcatatatga
     2521 aaacagaaga aaacctgcta tatttaatac aataaaaagt aatgaaatca agatacttga
     2581 acctataaat cgcctcaata tgtactttac actatccaaa attaaatcac tcctcttgat
     2641 ttcttttatt ctaatatcta aaattaatta atcatcaact tatatccaag accccttact
     2701 gtaataagat gtttaggtgt agatggagtt ttttctatct tctctctaac tcttctaaca
     2761 tgaaccataa gggtattttc atatccatac atatcatctc cccaaatggc ttgacatagt
     2821 gaatcattag taacaattct ccctttattt tcatacaact ttaaaagcaa cgaatgctct
     2881 ttagctgtta aagaaatctc ttgcccatct ttctcaacac atgcactatt taaattcaca
     2941 acaacagaat ctcccagttt aaatactggc aactcctctt cttctatagg cacatataca
     3001 cgatttaata tacccacaag ccttaaagta agttcctttg gtaaaaatgg ctttactata
     3061 taatcgtcag cacctaagcc caaaccaatc aatctatctt catcttcacc tcttgcagag
     3121 agaaaaatca ctggtatttt agatgtctct ctaatttttc tcataataga aaaaccatct
     3181 ccatctggca atacaacatc taaaattgca caatctggct ttacatttct aaatacccta
     3241 acagcttcct cataacttga tgctaaaaat actctactaa atccctcttt tctcaggatt
     3301 tcatctatca tttttaataa ttccttgtgg tcatcaacca caagtatttt tttatctttt
     3361 attgactcca taatcatcac cctcctttag tataccatat acccattttc acaactttgc
     3421 ctaaatagac ttttaaggtt attgtaaggt aaacttcagc taactgaaat gtaaccaagt
     3481 tattatactg atataagtta aaagaatcaa taagcacaga ttaaaaaagg ggatgaaaca
     3541 tatggaaatg ataattagaa cacaaagact ttcaaaggaa tacaataaaa tatttagagt
     3601 aaaggatata gacctaagag ttccacaagg agctgtatat ggttttttgg gtcctaatgg
     3661 agctggaaaa tctaccactc ttaaaatgct tcttggactt gctaaaccca cacaaggaaa
     3721 tattaatatt ttaggtaaag agttaaatga aaaaaataga atatcaattt taaaagatat
     3781 aggttctttg atagaatctc catcatacta tggtcatctt acagggcttg aaaacatgac
     3841 cataatgcaa agactcttag atttacctaa aaaaaatgta aatgaagcat taaaaattgt
     3901 aaggttagaa aatcaaaaaa ataaaaaagt tagtcaatat tctttaggta tgaagcaacg
     3961 tcttggcatt gctatggcaa taatgaagtt tcccaaatta ttaatacttg atgaacctac
     4021 aaatggactc gacccagcag ggattgagga aattagagaa ttaataaaat ctctaccaga
     4081 aaaatacggg atgactgttc taatctctag ccatctttta agtgaaattg accaaattgc
     4141 cacatcaata ggaataataa atcatggcga actggttttt caagatagca taaaagaact
     4201 tcataataga ggtcaaagtc agattgctat caaaactaag aatgttgtat ctgcacaaaa
     4261 actattaaat actaaaggat atatgtcact tatacaagat gggtacttga ctattgaaaa
     4321 tttaaaagac tcagatgtag ctaaaataaa cggtatgctt gtccattcaa atatagatgt
     4381 atttagaata gaagaacata aaaaaagctt ggaagatata ttcttagaac ttactggtaa
     4441 ggcggtgact ttataatgaa ataccttggt ctagaatttt ataaacttaa aagaaagaag
     4501 attattctga tgaccttttt atttgtagct gttgaaataa tgtggtgtat cgtaaattca
     4561 aatagggcta ttacacgtaa tccagatatg ttaggtggat ttgaatattc ctatatgctt
     4621 atgagttttg caagtttaaa tggtctattc tttcctatct taatatcaat aattacatca
     4681 cgtataagcg atatagaaca taaaggagat acatggaagc ttttaaaatc ttctgtgaca
     4741 tctttaaata gtatttattt atctaaattt ttatgttctg ctattttggt atctatatct
     4801 gtattgatgc aagtgttatc tattatgtta tttggacatt ttagaggggt tattgagtca
     4861 atttctgtat ctttactttt aaaatacaca ttaggaacaa ttcttgtaag tattgctatc
     4921 attgcactac acctatggat tgcaactgta attccaaatc aaatgattgc aattacattt
     4981 ggcatgattg gtagttttat aggtttgaca tcaggtttgt tttatcaagg tattcgtaga
     5041 ttgtttatat ggtcttatta cctagagtta tcacctttaa gttatgctta tgataatgtt
     5101 ttaggttcat ctgtctatag aattgatatg aatttttcta ttacgatttt agttttctta
     5161 attggaatgc taatttatta tattggaaga aatcatttat taaaaaaaga agtataggag
     5221 ggatttaaat gttaaggaag tcagttttgg gagaaattct aaagttaaaa aattctttta
     5281 tatggtatgt attattagct ttgccactta taagtgtgtt gattggttct ggtaattttt
     5341 atctaaatca aggcatactc aaaaaagaat ggtacagctt atggactcaa gttagtcttt
     5401 tttatgggga atttttcttt cctatcttaa tcgcaatctt ttgtgcatat atttgtaggc
     5461 ttgaacatat gaatcataat tggaataatg taatgacact gccagttaat ttaaaaaata
     5521 tctttttatc taaacttaca gtagtttcaa tacttacagc tattacacaa gttttctttg
     5581 ttatctttta tatagttgca ggaaatatgt ttggtttttc tggtagtgta cctaaagaat
     5641 tgactggttg gattgctaaa ggttggatta tttctatttc aatagcttct atacaattat
     5701 acatgtctat aaagattaga agttttgcaa ctcctattgg tattagtctt tgcctttctc
     5761 tatttggtat gggattaata gtagcaaaac ctgctgttgg tatatttttc ccttattcta
     5821 tgttaggtag tgctatgggg gttataaagc aatctgcttt aaatgttaat gacactatag
     5881 ttacaatatg tgttgcattt attactacta tagtattttc tgaagttgcc aatagaaatt
     5941 ttagaaagaa tgatgttatt tcttaatggt aaatgctaga tattttttgg tttgaaattt
     6001 atattctttt tagttgaaat ctatatccat tttatttaaa aatatatatc ttttatttga
     6061 attttatatg ttttatctac tcgctatata atagatatat tcctaaaatt aaaaaatata
     6121 taataatgtt attatttaaa attattatgt attatattaa aacttaatg
//
LOCUS       DAEQAF010000146         6157 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.150, whole genome shotgun sequence.
ACCESSION   DAEQAF010000146 DAEQAF010000000
VERSION     DAEQAF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6157
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.150"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(150..2744)
                     /gene="clpB"
                     /locus_tag="KRN00_003434"
     CDS             complement(150..2744)
                     /gene="clpB"
                     /locus_tag="KRN00_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBH1829258.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNIFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(2781..3377)
                     /locus_tag="KRN00_003435"
     CDS             complement(2781..3377)
                     /locus_tag="KRN00_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829259.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(3394..3798)
                     /locus_tag="KRN00_003436"
     CDS             complement(3394..3798)
                     /locus_tag="KRN00_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBH1829260.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            4165..4539
                     /locus_tag="KRN00_003437"
     CDS             4165..4539
                     /locus_tag="KRN00_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1829261.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            4536..5399
                     /locus_tag="KRN00_003438"
     CDS             4536..5399
                     /locus_tag="KRN00_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1829262.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            5399..6037
                     /locus_tag="KRN00_003439"
     CDS             5399..6037
                     /locus_tag="KRN00_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBH1829263.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
BASE COUNT         2033 a          933 c          706 g         2485 t
ORIGIN      
        1 taaaatactt cctttgagtt aaatttaatt tggacatatt gacttaaaaa tgttttatta
       61 atttgataaa atatttcttt tcctatagtt tataaataaa aatcagctga gcaaaatatt
      121 tagtatatta tgctcaactg attcctttat tatttaacta aaacttcaat attttcatct
      181 tttccatcta taactatagt acatccatta tacacatctc cagcaataag tttctttgca
      241 attatagttt ctaatgtatt tcctatatat ctcttaagag gtcttgctcc atatacaggg
      301 tcatatcctt ctctcaccat aacatctttt gctgaatttg taacttcaat agtaatatct
      361 ttttctttta atctattttt taaatctttc ataaatatat ctataatttt cttgatattt
      421 tcttggtcta aaggcttaaa cattataata tcatctactc tgtttaaaaa ctcaggttta
      481 aatctatgct tcatttcatt cattactaaa ttgttagtag tctctgttat atttcctcct
      541 gcttctaata gataattact tcctatatta gaagtcatta ttataagagt atttttaaag
      601 tctactgtct tacctttatt atcagtaagt ctaccatcat ctaatatctg taagaaaatg
      661 ttaaatacat cctcatgtgc tttttctatc tcatcaaata gtattacaga ataaggagca
      721 cgtctaactg cttctgtaag ttgaccaccc tcttcatatc ccacgtaccc tggaggaggt
      781 ccaactagtc ttgatacagc atgtttttcc atgtattcag acatatctat tcttattata
      841 ttatcttcac tatcgaataa atttctagca agagtttttg caagttcagt tttaccaaca
      901 cctgtagggc ctaagaaaat aaatgaacca attggttttc tttcatcttt taatcctgct
      961 cttgcacgta ttactgcatt tgaaactgct gtaactgctt catcttgtcc aataactctt
     1021 ttatgaagtt catcttctag tttaagtaat ttttctcttt ctccttcaac tagtttagtt
     1081 actggtatac ctgtccactt tgatacaatg ctagatattt cttcttcagt aacttcttct
     1141 tttaaaagag aattttcaga accgtcattc atattttctt cgtactgctt tatttgttct
     1201 tctaacttag gtatttcacc atatttaacc tctgctgctt tgttgaaatc atattctctt
     1261 tcatactttt cagctttacc tttagcttcg tctaattgag cctttaagtt tttaatatct
     1321 aatatttgac tcttttcttt ttcatatttt gctgtcattt catcattttt agattttaac
     1381 tctgctattt ctttttgaat atcatccaat cttgatttac ttttatcatc attttcttta
     1441 agtaatgctt ctctttcagt ttctaatgta aataactttc ttctaacaac atctaattct
     1501 gttggcaatg aatctatttc actacgaatc atagctccag cttcatcaat taaatcaatt
     1561 gctttatctg gtaaaaatct atcttgtata tatctatgag aaagttttgc tgctgctaca
     1621 atagcattat catgtattct tactccatga tgtatctcaa atctttcttt taaacctcta
     1681 agtatagata ttgtatcttc aacagtaggt tcttctgcaa ttacaggctg aaaacgtctt
     1741 tcaagagcct tatctttttc tatatacttt ctatattcat caaaagtagt tgcaccaata
     1801 cagttcaatt cacctcttgc aagcataggt ttaataagat tacctgcatc cattgaacct
     1861 tctgttttac cagctccaac aatagtatga atctcatcta taaacagtat aatttttcca
     1921 tcagaacttt gaacttcttt taaaactgcc tttaatcttt cttcaaattc acctctatat
     1981 tttgcaccag caattaaagc tcccatatca agtgagaata caatcttatc ttttaaacct
     2041 tctgggacat ctcctcttac tattctctct gctaaccctt ctacaattgc agttttacct
     2101 acacctggct caccaatcaa tacaggatta ttttttgttc ttcttgataa aattcttata
     2161 atccttctta tttcttcatc tctcccaatt acagggtcta atttattttt cttggctaaa
     2221 tctactaaat ttgttccata tctagcaagt gcatcatatg tgccttctgg gtcttgtgtt
     2281 tctactcttt gactacctct cacttgtgat aaaatattta aaaagtcatt cttatttata
     2341 ttatattgtt ttaatatttt accaacagct gattttgatt ctgtttccat cattgcaagc
     2401 ataacatgct ctacacttat atatgaatct ttaaattctt tagaaatact ctctgccttt
     2461 ataagcacct catttatttt tctagtagct gatactcctt gtgagtcagc accttctcca
     2521 tatacttttg gaagcttatc aatttcaaag tttacagtat ttctcaaaga atcaattgat
     2581 atattcattt tttcgattat atttggtatc aatccatcct cttgattaat aagtgctgag
     2641 aaaagatgaa ttacatctac ttgttggtta tgatttttta ctgcttcgtt ataagcctca
     2701 tttaaacttt tttgaactct taaagtcatt ttttctacgt ccatataaat ccctccattt
     2761 taatattata tccaaataaa ttaaattctc tcatttataa ttattgattt tctaagctct
     2821 aaaagactat caagtaaatt ctcgtttttt tgtatatcga aactcaatgt taaattaaat
     2881 gttccatctg aattaaaaaa atcgaatact tcttttgatt ttgctattaa atacaagtct
     2941 tcatctataa gtcttttttc acctattaat aaatactgac atttatctat aaaactcttt
     3001 ttaaaatcaa tagtgtatag attttctaaa atattatatt gataaatagc aatattatta
     3061 aacactttta atatgtttga atttacaaaa ttgtaaattt gattattgtt atacagtgat
     3121 atttgttcgt atatatattc cctaaataaa gggtgaatgt tttgcttaag ttttaaagta
     3181 acttcagctg gtatttcaaa ataaagcttc cagtacttag agttattttt ttctaaaata
     3241 aaagctactt tgttcaaact ggtagaacta atctccttta gtgtacaatt aaaattatag
     3301 tgtctcaaac tagttttttc attctcaaat acatagtcaa accactgtag aacatttcta
     3361 tcaagtttta aactcatata aaaaccttct tccttattta ctaaccttat taggtctttt
     3421 tatctgatta tattctgcta ataaactttc tttatcagct ctactacctt tatatgctat
     3481 atgtggattt atcatatact caccattttt cactctttgt aaaaaatcca tttttttcag
     3541 ctccgtaaac aatgaagata aagaagtttt tggatattca aattcacaag ataattcata
     3601 taatgttttt ctaatcttat tatttttatc catagagttt attaatttta atggaattaa
     3661 atccctctta gtatacattc cttctactac tttaatataa ttcttaaaac aaacattcat
     3721 atacttactt ttattcataa ctaaactttt gctctctgta tattcctgat ttaaatcctt
     3781 ttttaatgtc ttatccaaat taaatatctc ttctcactct ccttatctct aattgataat
     3841 ataaatatat tacaaaaaaa tatgtatgtc aaaactgaaa atgcaaaaag ttcagcttat
     3901 aagtaaactt ttatttagct ataagctaaa ctttattatt tttttaattt agtatttcca
     3961 atttattggc aggatttttg aacaatattt ataaattttt taaaaaaatt tatatctatt
     4021 taatatggca gactttcata aaatacatta catttattaa atgtataata ttggcaatta
     4081 gttttttcta aaatcagttg acatattata tatatattta tataatgtgt atatactata
     4141 tatacaattt aaggaggtgt cttattgaat atagttatta gtaattcgag tgggaagcca
     4201 atatatgaac agattactac acaaattaaa agtatgatta taagtggaga gttaccagaa
     4261 ggctcagctc ttccaagtat gagactattg gcaaaagaac ttagaataag tgtaattact
     4321 acaaaacgag catatagcga tttagaacga gacggattta ttgagacagt tactggtaaa
     4381 ggcagttttg tatctagtaa aaacatggat tttgtcaaag aagaacaatt tcgtttaatt
     4441 gaagaatacc tacaaaaagc agttgataca gcaaaaagta gtgatattac atatgacgaa
     4501 ttaaaagata ttttattttt attatataaa ggagaatgat aagtatggat gcaataacta
     4561 taaaaaattt aaataaaact tataaagatt ttagcctaca agatatatct ttttcagtac
     4621 caaaagggag tgtaatggga tttgtaggtg aaaatggtgc aggaaaaaca actacattaa
     4681 aagcaatttt aaatttaata tcttatgata gtggaaatat agaaatcttt ggtcttgata
     4741 gtaaaaaaaa tgaaaaagaa attaaagagc aaattggggt tgtatttgag ggaagcaact
     4801 ttcatgaaaa tttaaacact gaccatgttt caaaaatcat gagtaaaatc tataaaaatt
     4861 ggaatgacac attatttaaa gactacttaa aaaaattgag agtaccagac aataaattaa
     4921 ttaaggagtt ttcaaagggg aataagatga aacttagtat tgctgtagcc ttatctcata
     4981 aaccaaaatt attaatacta gatgaggcaa ctagttcact tgaccctatc gttcgtgaag
     5041 aaatactaga tatattttta gattttatac aagatgaaga acactctatt atcttatctt
     5101 cacatattac aagtgattta gataagatag cagactatat tacatttata cataaaggaa
     5161 aaattgtatt tagtgaaaat aaggatgaat taattgatac tatgggagtt ttaaaatgta
     5221 aacctagtga ttttgataac ctttcaagag aggattattc atattatcgt aaaagccaat
     5281 ttggatatga agtacttctt aaagataaac atagatttat ctcaagacat ccaaactgta
     5341 ttgttgataa tacgtctata gaagaaatta tgttatttta tgtgagaggt gataaataat
     5401 gaaaggtcta attttaaaag atttacttaa tttgaaagga aatataaagt ttatactttt
     5461 attcatcatt atgtttggct ttatgtcttc tttaggagat ggaaatgtta ataactttat
     5521 aggtgttatt atagttttat gtactacaat gattgtttca acattttcat atgatgattt
     5581 gaataaatgg gatagttatg tacttacaat gcctattaat cgcaatgata ttgtattaag
     5641 taaatattta actatgttaa tatttagctt tataggtgtt cttgtttcac ttattgttag
     5701 tgtaactatt ggttatttta aaaatacact tatattaaat gaaacactac ttattaatgc
     5761 actaatctta tcaatttcag tatgttttgg tagccttatt ctaccactta tttataaatt
     5821 tggtacagaa agagctcgtt tattaatgat tttatgcttt ttagttccaa cactagcttt
     5881 attagttttt aaaagtattt tagaaaatat tagttcacct atttctatag aaattatact
     5941 taatacacta gtatattctc ttccatttgt tgctatttta ctatttgtga tttcatattt
     6001 tatatcatca aaaatctata gtaaaaaaga agtataaaat atactatata tgtttctgta
     6061 tttaagtatt taaataaaat actatcgagt ttattttggt agtattttat tttttaatta
     6121 ttaatctcta ctaggtattt attattttat tacttat
//
LOCUS       DAEQAF010000147         6153 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.151, whole genome shotgun sequence.
ACCESSION   DAEQAF010000147 DAEQAF010000000
VERSION     DAEQAF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6153
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.151"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(402..986)
                     /locus_tag="KRN00_003440"
     CDS             complement(402..986)
                     /locus_tag="KRN00_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBH1829264.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
     gene            complement(1308..3152)
                     /locus_tag="KRN00_003441"
     CDS             complement(1308..3152)
                     /locus_tag="KRN00_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBH1829265.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYHSEIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASNAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNRHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            complement(3447..4409)
                     /locus_tag="KRN00_003442"
     CDS             complement(3447..4409)
                     /locus_tag="KRN00_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBH1829266.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            4600..5151
                     /locus_tag="KRN00_003443"
     CDS             4600..5151
                     /locus_tag="KRN00_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829267.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
BASE COUNT         2216 a          934 c          594 g         2409 t
ORIGIN      
        1 aaataaatgt tactcttatt aataaaaaaa attataacca cttttgatta ctaatcaaaa
       61 gaaaatatct aagtaaaata aaaattatat ttattaagct ttatgtatta tagtatttta
      121 ttcttactta atcatcatac tatagcaaaa tactaaccta aaagttagta ttttacttaa
      181 aaataagtgc ttattcaaac atcaaataga atatatacta ttataaataa atctataaag
      241 gaatgacttt tataaaaaaa tggtggaaat gcaagacaga agtgataaaa actacattcc
      301 acaaaaattt aacaaatgaa tatggatgtg aaagtattag aaaataccct atgtataaag
      361 taagaaaggt gttttttgag attttgcaag aaaatttaac tttatttatt ttctcgaata
      421 atacggcatg gatttccgta tgcaatcata ttacttggaa tatcttttgt aacaatactt
      481 cctgcaccta taactacatt atctccaata gtaacacctg gcatgataat agcacccccg
      541 ccaatccaaa cattatctcc aatagtaact ggagctgttt gagttttaca aaattcaaat
      601 gaaccatctt ctttggcatt accaaatcta tcaccagcat tagttggatg aaatgcagta
      661 tatatttgta cgtttggtgc gattagtgca ttatcaccaa tgataatttt attatcatct
      721 aaaaacgtac aattcatatt gacttcacaa ttatttccaa aataaatatt atttccataa
      781 tctacataat acggtgcagt aatccataag tttttaccct taccaccaag taattcattt
      841 aatatttttt cttttttttc caaatccgag gaatctgttt ggttataatc tcttactagg
      901 tcttttgctt tatgccattg agttaacaac tcaatatcac cacaatcgta aagttctcct
      961 gccaacattt tttctcgctc tgtcatgttt ttaatcctcc aaatttatat tgtttttcat
     1021 atatattcta gcataagatt tattaattta tatattttac ttatataaaa tttaataaat
     1081 aacaagattt attaaatata cagttgacaa tctatctctc tgtcatctta aaactctttt
     1141 aactgtaata atctcagagc aattttttca cttttattcc ttgtttatag ctgataagca
     1201 caatttttat aagaataacc ttaatttaac aaccttattt atgttaaaaa gagatattat
     1261 tgattttaat aatatctctt ttactggata atacaattat agaatattta aaataaataa
     1321 tctgacactt gactaataaa tccatttttc ttccaataaa ttgcactctc tataaggtat
     1381 ggattatctg taataatact atctacattt aggtcaagca ttttctcaat taaactgtca
     1441 ctattaacag tccaaacgaa gatttttttg ttcattttat gaatcttttc tactactgtt
     1501 ttattaacaa aagttgattc aattccatat atatcaacat aatttaactt tgaaaaatca
     1561 ccatatgcaa ttgccataaa atagcatgtc aataaattct catccagttt ttttactttt
     1621 tgtaatatag ttttatccat agatgcaact atacattgat tttcaaaatt attttcttta
     1681 attaactgaa caactttttt tactacgtct cccttttcat gtctattaag ttttatttct
     1741 attaataatt tcaccttacc tttagaatat tttatcattt ctttgagtgt tggtatcttt
     1801 tccccaacaa acttttcatc ataataacct tttccataat aataaaagct tcccgcatca
     1861 tatgtcttta cttcattata atttacatcc caaacatttt tatctactcc tgtagttctc
     1921 ttaaagtttg aatcatgaag tacaataagt tctccatctt tagtttcttg aacatctatt
     1981 tctgcataat cagctttagc atttgaagct tcttctattg ctgccaaagt attctctgga
     2041 gccatttcag ctcctgctct atgagcaatt gctgttgtat aaaatgaaaa tgacgtatta
     2101 aacataccat ttatatgtga agaaaatgca actgactcta tataagaaat caataatatt
     2161 aatactaaat taaaaacaat ttttgatata gattttttct cttttttaat attattttta
     2221 gaaatactta ctcctttata ttgataataa gttgctgaga taaatccaat gtccaatata
     2281 aaaatgaata ttgataaaat caatctaaaa tattcttcaa atgcaataca tctatttata
     2341 aatacattct tcaaaaattc catatcagta caatatttag tccatatgcc tataaatata
     2401 atttcactat gataaatcgc atatccaata atagctacta ctaaagataa tattaatgaa
     2461 taaataattg ttcttataat ctttcccttt ataagattaa cactttcttt tcttgctctt
     2521 ttaaaatttt ctgtatttaa agttatctca tgaatgctaa aaatccatct aataactgaa
     2581 atatatatta ttaaaagaaa aatcatatag attatattta aaattatatc agactttata
     2641 taatctaata tgtactctgg tatttgtatt tttcctataa accctgaaat taaaactgta
     2701 tttactaatg gaattattaa tatcacaaat ataaataata gtatattttt aggatataac
     2761 aattttatag agttctcaaa tgatatttta aagagttcaa ataaccctat tttttcatat
     2821 tttatcgatt tattaaaaca aataattaca gaggtaaatt caaaaaatgc ataaaaagct
     2881 agtattataa ctgatagtat tatcagaact attgacatgg gattggtcaa aacttttata
     2941 aaattatcca tatttaggta gactatatgt aaacttttta ttaaaatatc aaatatatat
     3001 ctaatagatg gccatataaa aaataaggct aatcctttat gaaataattc aaataaaatt
     3061 aatgtactaa aattatattt tattataaaa acaagtttac ttaaaatatt tttacccgta
     3121 aatataaaat ttcttaaaat tctcttttgc atttttatct ccttgtatct atttgttcta
     3181 attttatcat atgttttaaa tacatttaga acattaatat gtattattcc aagttatgat
     3241 gtataaatgc aaaaacacat actctttttt attgcatagc taatcatcaa tatctatata
     3301 gcttaatact tataagtagg atactccata tttacaaaat aaaaaagtat ctcctttata
     3361 actttcaaaa attacattga gatacttttt ataatttaaa tctatatact taatttaaaa
     3421 aacattgcat aactattgtg ctattattac aattcttcat ataaatcagt acttaaatat
     3481 tttaaaccac tatcattaag agttaaaact atattttttc ctttttcact gctctttaat
     3541 aacttaattg ctgcacatac atttgcccct gaagaaaatc ctgcaaatac accttctaat
     3601 ttagctaatt ttcttgctac atcagttgcc tcctcgtctg taacttgaat ataaccatca
     3661 ataagtttct tgtctactaa tggcaaatcc atagaatatc ctccaccttg tattttatgc
     3721 ccttggtcag ttatttcttt acctgaataa attgctgctg tttcaggttc aacaacataa
     3781 catttgatag aagaattatg ttttttaagt gtttttgaac atcctgcaaa agtactacca
     3841 cttccaagaa aatctacaaa tacatcaata tttccatcca attgttccca catttcttct
     3901 gctgtatact tttcatgtgc atgattacaa gcttctaaat taaattggtc tgctctaaat
     3961 gcatttcttt cttttgctat tttttgagcc tcaatttcta caagtgccaa atcttcacca
     4021 gatacctgtc catgaactga attaggcatt tggtctacaa gaactacttc agcacctaaa
     4081 gctttcatca ttcttgctct ttccatagaa tttccttttg acatacacgc tataaattta
     4141 tatcctttac atgcacaagc tattgctagt cctgttccag tattaccact tgttaattcc
     4201 acaactgctt gacctggaac taataaacct gcattttctg cttcggtaat catttgtaat
     4261 gctacacggt cctttttact aaatcccgga tttaagtatt ccatctttgc ataaatatta
     4321 ccttgaactc caaattcatc tgctattttg gataaatgta acatatgagt attgcctata
     4381 gcctctgtaa cattattaag tacacgcatt acaattcccc cttaatctct caactatcat
     4441 ccgttgaaaa acaactcttt atgcagtata atttatatta cggatgtaca gtatatttaa
     4501 cgttcattat attatacatt tgtaaattat aaataatgtt aaataaatta tacattcgta
     4561 aattatattt gtcaataatt tacattttaa ggagttacta tgagtattaa tactgttatt
     4621 gctaaaaatt taaatagatt acgtaatgaa cgtaacttaa gtctaggtca acttgctgaa
     4681 ttatctggcg taagtaaagt aatgctttcg caaattgaaa agggagactc aaacccaaca
     4741 gtaaacacaa tttggaaaat tgcaagtgga ctaaatgttc catatactgc aatactggaa
     4801 caacctcaaa atgaaacttt tattgtatca aaaactgata tagatgtaca agtttcagaa
     4861 aataaagatt atcgtcttta ttgttattat cccaatacac caactagaaa cttcgaatta
     4921 tttcaaatgg aattagaaga aggtcatagt tatacatctg ttggtcattc tgaaaaatca
     4981 caggaatata ttatgattat agaaggtcaa ttaaaattag aagtaaatga ctctatttat
     5041 caacttagag aaaatgactc tatttgtttt tcagctgaat caattcatac ataccataat
     5101 caaggagaaa aaacattgaa agcagtaata ataaattatt atccagttta gtcatgccat
     5161 ttaataatag aataattatt ttctatacaa aaagataaat cctttgatta ggatttatct
     5221 tttttatttt atttttcttt ataaattcat tatatatctt tacactttta tcaattatgt
     5281 tataataagc ttatataaaa gttttatatt tttgacaaat ggagtacaaa atactccttt
     5341 ttctttttta ctattgtgat aattatttag ttagtattaa aatattatca cttaaaacaa
     5401 atacaaaacg tctcttatat gtacattttt cattgttgta ataatgattt gtgtatgtat
     5461 ttctcacaat tggagtgctt atgcactctt tttaaatacc tttattacca taacctaaaa
     5521 gctattttat tatccctttt agtttatttt taagtagtta aataaattat tttatatttt
     5581 tttcttcatt tatatgaaac ttttgtttta tcactatatg cactttatat ttactacaaa
     5641 taacacataa gcttactttt atcataagac tcctatatct aaatataatt taagaggtta
     5701 aataattgaa tagtatatta aaacataatg gtaatgacaa aaatataaaa atctttatag
     5761 tcataaattt tatcttatca tttttatcct ctctattaaa ataattatct tgataaaatg
     5821 tagctctatt ttgataacct gtttttaaaa ctccattttg aattaacagc aatataaaaa
     5881 agattgctaa taaaataaag ttataatttt tttcttttaa tctaaaatta gctataataa
     5941 caatgaaact atataaagca tataaaaatt ttttcataaa aaacacctaa attctatatt
     6001 tgtattttat attgagccaa atctaatttc tgtatattta ttaagtgtag ttctagttcc
     6061 tattgtaata gcattaaata ttttttaatt tttattttca aagggcatct ccttatattt
     6121 aaattatagt atgaatattc ataaatttca atc
//
LOCUS       DAEQAF010000148         5992 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.152, whole genome shotgun sequence.
ACCESSION   DAEQAF010000148 DAEQAF010000000
VERSION     DAEQAF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5992
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.152"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            173..985
                     /gene="modA"
                     /locus_tag="KRN00_003444"
     CDS             173..985
                     /gene="modA"
                     /locus_tag="KRN00_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1829268.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            995..1786
                     /locus_tag="KRN00_003445"
     CDS             995..1786
                     /locus_tag="KRN00_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829269.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQIFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGCNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFLSLTCLMLFEIFFNREVDKN"
     gene            1788..2483
                     /locus_tag="KRN00_003446"
     CDS             1788..2483
                     /locus_tag="KRN00_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1829270.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAEPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            2470..3201
                     /locus_tag="KRN00_003447"
     CDS             2470..3201
                     /locus_tag="KRN00_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829271.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNSHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            3515..4315
                     /locus_tag="KRN00_003448"
     CDS             3515..4315
                     /locus_tag="KRN00_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBH1829272.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            4855..5571
                     /locus_tag="KRN00_003449"
     CDS             4855..5571
                     /locus_tag="KRN00_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1829273.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
BASE COUNT         2334 a          726 c          845 g         2087 t
ORIGIN      
        1 ttaaaaataa aataactacc tatggaaatg acattatgaa tagatttttt cttaactata
       61 cataacaaaa cataacaaaa cattataaaa cataacaaaa acttagacat cgttttctta
      121 gtatgatata ctaaaaaaga atttacacta atttaataag ggggaatatc ttatgtttaa
      181 aaaactttca gtactagctt tagctatgat tatttcatta agtattactg catgtaattc
      241 taaagaaaac aaagctaatg atgaatctaa tactaaagtg acaacagctg atgattcaaa
      301 agaaaaagag actctttttg tctattcagg ggcaggttta aagaaaccaa tggatgaaat
      361 agcaaaaaaa tttgagaaag aaaataatgt caaagttgaa tatagctatg caggttctgc
      421 acagctaata gctcaaattg agacaagtca caaaggagac gtatttattg ttggttctga
      481 accaatttat tcaaaggcct ttgaaaaaga acttgtaggt gaacataaaa cggttgcaca
      541 tcatacacct gcaatagttg tacctaaagg aaatccagct aatattcaaa aattggaaga
      601 cttaaataaa gatggagtta aacttatttt gggagacaaa gagtctaatg ctataggtaa
      661 gactacacaa aaaatacttg aaaaaaataa tttaaaatct ataaatgata atgttgtctc
      721 tacagctgca actgtaaatg aaatgattgt acagttaaca tcaagtaaag ctgatgctac
      781 aatagccaca aaagattcgg tctttggtaa tgaagatgta gaagttatag aaattgccca
      841 agataaaaat atagaccaac tcatatcagc aggaatcgta aactatagtg ataaaaaaga
      901 tttagctaat aaatttataa attatataga gtcagacgaa gctaaacaga tatttaaaaa
      961 atatggtttt gaacctgtta agtagtgatt aaacttgaaa aataaatttt ttactactct
     1021 acttactgga ttttttgcta tagtcttttt gtttattgta tcaccacttc ttatgttaat
     1081 cattaaaggg ataagttatg ttcctatatg cttaaaatca gtggaagtac agtatgcaat
     1141 aacacttagt attaaaacat ctttaatatc tactatagta tgccttttat tagctattcc
     1201 agtagcatat tttttacata ttactaaatt accatttaaa aaactgatta tacagataat
     1261 aaatctccct atgtctcttc cacacttagt atcaggaatt gctcttttac ttttgtttgg
     1321 aagaatgggg attggagatt ccatttataa gatttttaag cttgatttta tatttacaaa
     1381 gcaaggtata gttttagcac aaatatttgt aaatcttcca cttactatta aaatacttca
     1441 cacttcatta aatgaaagta atgaaaagat gatatttgtt gcacgtaccc ttggatgtaa
     1501 tagttgggaa gcatttagat ttataattct tccaaatcta aaaactggaa tcatatctgc
     1561 aactgtaatg acttggtcaa gagcacttgg tgaatttggt gcagtagcta tgatagcagg
     1621 ttctacacgt atgaaaactg aaattattcc tacatctata tatttaaata tgtctactgg
     1681 tgatatagac attgctatcg gaatagctgt aattttgata tttctctcac ttacatgctt
     1741 gatgcttttt gagatatttt ttaatagaga ggttgataag aattaatatg ttaaaaataa
     1801 aaaatttatc tcttgattta cctaatttta aattacaaga aaatagttta aatattaata
     1861 atcatgaata ctttgtttta ttaggagcta gtgggtcagg taaaactcta tttctagaaa
     1921 cattagcagg aagatatcca tctgctaaag gaaatgtatc atacaaagaa aatttaatat
     1981 caaacttacc tccagaaaat agaaatatag gatttgtata tcaaaatttt gaattatttc
     2041 caaatatgaa tgttgaagat aatataaggt ttccacttaa attgagaaaa atacctatag
     2101 atgaacagat tcttaaggct aaccacttgt ctaaattaat gcagatagaa gatataaaaa
     2161 ataggtatcc taaaaattta agtggaggcg aaaagcaacg agttgctttt gcacgtgcct
     2221 taatagctga acctgatata ttacttttag atgaacctat gagttcattg gattatatta
     2281 caaaaaaaca tataagcaaa attttgaagg atgtctacat aaaatacaaa ccaacagtga
     2341 ttcatgttac tcatgatatt tctgaagcaa tgttttttgc tcataagata ggaataatga
     2401 acaatggaaa aataaatcat atttttgatt taaatgaaga aataaaaaat aaaggagaat
     2461 cttttttcta tgaatatatt tgatattttg agagattatc tattagtaca agtcgataaa
     2521 tataatttaa atatggatat gataagtatt gtgtccaaat ctctatcttc aaaagaagca
     2581 attggaaata ctaagcgtaa agatttccca attatagttg gtaaagaaat aatgcttgaa
     2641 gctgacttta aaggagctaa aggacaagca tttacttcta ctccatctac atttgaaggt
     2701 tctttaaaag acatattatc attagattta catgacaatt ctcatgatag aagtcttttt
     2761 atagcatcat taaatgcagt tatgaaatac ttaggcaaga cggatagaac cattcattgt
     2821 aaaaataacg agccagaggt atgtgcaaaa aaattccctg agtttataaa aatggaattt
     2881 ggtaatccaa aagtagcaat tataggatat caaccagcca taattgataa tattaaggac
     2941 tttttcgaaa caagagtatt agatttaaat cctgaatttg tggatactat tcaatataat
     3001 gttaagattg aagatggtat acgagattat gaagatgtaa tatcttgggc tgatttagtg
     3061 atttgcacag gaagtacatt atgtaataac tcaattataa attttctatc acttaacaaa
     3121 ccagtttact attatggaac tacgatagct ggtgcatcaa atattttagg tttaaaaaga
     3181 ctctgttttt gtagtaaata agcaatcata tcatcaagga gtacacaaat atatatgtgt
     3241 actctttaaa tttaaaaagt tattactttt attctaagta ctaaagtaaa attctattaa
     3301 aatgaatccc gaataaatgt acaatccctt taaatctcaa ttcctatcaa tcattaatat
     3361 tttgattagt cttatacata aatgttttct ttattttaaa ctaataaaaa aattttattc
     3421 cattaatcta ctctatattt ttcagcattt aagaaataat ttttagtact ttgtttgata
     3481 atataactaa gacaaccttt caggagatga ttaaatgaca tttaagaata aaaaatttac
     3541 tataaataaa tataaaattc tatctattat tctagtttta tgtttgattt taaccgcttt
     3601 tagtagctat gtgaattata gtcataaaaa atttaaagat tatgttgtct tctatgttca
     3661 gcatcaagat gatgaagtgt tgtgggctgg gagtgctatt gttaatgcta taaaagaaag
     3721 aggaaaaaat catgtatttg tggttttagt atctactgga tgtggtatat ccgtctttga
     3781 taaatataaa aaatatgaaa acctaacaaa tatacaaaaa tcagaatata gaaatagaga
     3841 atttttagct tctcttaata gccttggtgt aataagggaa aatataatat tattaccaga
     3901 aacaaataca aatggtaata ctgacttcaa ttacatggaa aaaattgctc ttacatttga
     3961 agaaaaattt aaaaatgtaa ctcatatagc acatacttat aagttagatg accatttaca
     4021 acatttaaaa aatggttctg ttatccaaaa tttatataat gctggtaaaa taaaagatgc
     4081 taaatatttt gtaaaaccta aatttgctga taaaataact tttaataata agatagttta
     4141 taaagctcat tctactgaag actatgaaaa ggttaaaaat gcctgtcaac aatacaaaat
     4201 tgttgatgaa ttagaatata gagaaggtat tggctataag tctgaccata aatcatttga
     4261 taagttatta aataataaag atgttcctgc tatacttcat acacctaatt tataagaaat
     4321 atttattctt ttaatttaag ttataaaaag gaaattattt gagattttgt gatatagcac
     4381 tttttgtgct atactacttt ttctcataca actattaccc atatctaatt tcatcatctc
     4441 ttaaaatata taaagatatc atcattaaaa cctataagcc ttattaaatg ctttatacat
     4501 acctacatta aactacctgt ttatattaaa ctacattaaa ataaatattt gttataaatt
     4561 cttaataatt atgaaactca tttgttattt atatttgtta atatatgttt aaacctaaaa
     4621 aattaataaa ccaaaataac ataagaagtg tgatagatta ctctagatat tttcataaac
     4681 ttttaccttc agattaatat gggcgtctat acttttaaat ttactatatg cattgacaat
     4741 atattaaaag tactagtttt tatttcataa tgaatgggct tactgttttc taatacctct
     4801 ttttggtata aaataaaaat tggttaaaaa taaaatttca agggggttaa taagttgaat
     4861 caaaatatat tggttgtaga tgatgataga gagatagttg atgctataga gttctatttg
     4921 agacctgata actttaatgt tttaaaggca tatgatggac ttgaagcatt ggacatacta
     4981 atcgaaaatg atattaagtt aataataatg gatgtaatga tgcccaattt agatgggctt
     5041 aaaactacac ttaaaataag agaaaaaagg aatataccaa taattctctt atctgcaaaa
     5101 tcagaagata tggacaaaat tataggtctt aatatgggtg ctgatgacta tataactaaa
     5161 ccatttaatc cactagaact tactgctcga gtaaaatctc aacttagaag gtatataaat
     5221 ttaggtgatt ttagtaatac aaataactca aatgatacta attatattct aaaaagtggt
     5281 ggcctagagc taaatacaga tacaaaaata gtttctttag atggtgaaga aattaaaatg
     5341 acaccacttg aatataaaat acttacactt cttatgtcac gaaaaggtaa aattttctct
     5401 tctcatgaga tttatgaaaa tgtctggaat gaggatgctt atagttgtga gagaactatt
     5461 gctgttcata ttagaagaat tagagaaaag attgaaatta atccaaaaga accaaaatat
     5521 ttaaaggtgg tgtggggcat tggttacaaa attgaaaaac ttaattatta atgattctaa
     5581 agcaaaattt attttattat tattactgtt tctattagtt tctatattat ttgaagcagt
     5641 ttatgatttg aataataact tttctaatat taattattat tatagagagt ttgctctccc
     5701 ttatttttat tttttcggta ctcctgtaca tttgtcaaaa gtagaattag agtttgtctg
     5761 cataggtatt atattatcaa gttttttatt gactatacta tgttttacat tgtataaaaa
     5821 aaataaacaa actaaagtca aattcttaga gaatgtcata agcctttttt ctaaggtaaa
     5881 aatagaactt acacttatat taactttgat actattaacc ttaaggtttc atgcatttac
     5941 aagtaataaa atattttaca acactaattt aataatctac aattttataa tt
//
LOCUS       DAEQAF010000149         5904 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.153, whole genome shotgun sequence.
ACCESSION   DAEQAF010000149 DAEQAF010000000
VERSION     DAEQAF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5904
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.153"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            171..2195
                     /locus_tag="KRN00_003450"
     CDS             171..2195
                     /locus_tag="KRN00_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1829274.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKSLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            complement(2425..3612)
                     /locus_tag="KRN00_003451"
     CDS             complement(2425..3612)
                     /locus_tag="KRN00_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBH1829275.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(3814..5085)
                     /gene="brnQ"
                     /locus_tag="KRN00_003452"
     CDS             complement(3814..5085)
                     /gene="brnQ"
                     /locus_tag="KRN00_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1829276.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(5226..5879)
                     /locus_tag="KRN00_003453"
     CDS             complement(5226..5879)
                     /locus_tag="KRN00_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1829277.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
BASE COUNT         2203 a          928 c          704 g         2069 t
ORIGIN      
        1 tccttatctt gcaaaaataa ttttaaaata ggtttttata ggataaaatc ctaaaaaaac
       61 ctattattta atcaaatata taaatttata ctactatttg ttgtataata taacttgcct
      121 tatactttaa atactttaaa aataaatact attttgttag gagaaataaa atggataaaa
      181 agaagttaat ccttataaca tatgataaat tgaatagtga ccactacaaa gaagaattaa
      241 caaatttttt tggagacgaa ataatcatag aaacacaaaa tatacttgat ggaataaaag
      301 aaaatttaga gggagatgta gtgctttctc tatcaccttt aactagtaat tttttaataa
      361 aacattttaa ggaagatatt gaaattattc atggaacgaa agcactttca aaacttggat
      421 atgaaaaaat gatgaaacta cctccaggta caaaatcgtt acttatgaca accaataaaa
      481 cttcagcatt tgagatggct acttatctat ataaaattgg tataaatcat atagattttg
      541 taccgacata tccagattgt gatgaaatat atgatttaga tacagctata acaccaggtc
      601 agattagatt tataccaaaa tacataaaaa atattgttga tttaggttgg agaaaaatct
      661 cattagatac atatatgtca ttattagtag tattaaaatt aaaaaatgag aaatttatag
      721 aaaaactata caaattgtcc aaggagacac taagtcatga tttcttaaat acatcattag
      781 ataatatatc taaattaaaa actatacttt acatgaccat tgatgaaata ggtgatggtc
      841 taatattttt caacaccttt aacaaggtta cttttgtaaa taagtcttta cttaatatgt
      901 tggaactaga tgaaaaactt ataaaatcac cttccttaat ggaatatatg ccaaagagtt
      961 tcttagataa aattacaaag aacttaaata tcgataatat gattatatac atagacgaaa
     1021 tagataaaaa attcatactt tctaaaaaac cattttatct ttataaaaat atagagggtt
     1081 gcttaattac attaaaagat gtaaacaata tagaaatatt agaacaaaaa ataagaagtg
     1141 attctgtcaa aagaggttat gtagctaaat ataaatttaa taatattatt ggaaatagtt
     1201 ctattataaa agattgtatt aaaaaggcaa aaaaaatggc tcttacagat aatcctatat
     1261 taataacagg tgaaacagga acaggtaaag aagcctttac tcagtcaata cacaatcatt
     1321 caaatagaaa aaataaacct tttgtagcaa taaattgtgc ttcattacca agtgaattac
     1381 ttgaaagtga actatttgga tatgaagatg gttcttttac tggagcaaaa aaaggtggaa
     1441 aaaaaggatt attcgaatta gctcacactg gcactatatt tttagatgag ataggagata
     1501 tgccacatga tttacaggtt aaacttttaa gagtcttaca agaaaaagaa attagaaaaa
     1561 ttggtggtac aagtattatt ccaattgatg tgagaatatt agctgccaca aataaagatt
     1621 tagagaaatt aattatagaa aataaattta ggatggattt attttatagg ataagtatgt
     1681 tcactttaga tttacctcct cttagaaaga gattagaaga tatacctctt cttttagaat
     1741 catttttaaa agaacttccc tataaaaaca taaaactcga taagagtctt ttagaagctt
     1801 taaattcata cacttggatg gggaatatta gagaactgag aaattgtgtt gaatatatgg
     1861 cttacatggg ttccaattat cttacaataa atgatttacc tcaaaacata tcttcaaaat
     1921 taaataataa tcatatgtca agtaatatgt ccatattcaa tgatttaaac caatatgaca
     1981 aaaacatatg catttctatc ctaaaatcat tgcacatgaa accaatgggg aggacaaagt
     2041 taatgaaatt tatggaatat aatgtcacag aatacgaagt aagaaatatg ctagaatatt
     2101 tgacacgtaa tggatactta atttctagta aaggaagaaa aggctcatca ataactgaga
     2161 aaggcataaa aataatagaa aataatataa tttaaaccta tagtaattca tctttacttt
     2221 atcaaaattt atatataatt ataatttttt atttttctat aaatttttta taaaataata
     2281 aaacttattt atattaaaaa cgaagctatc tcaacatagg gataagcttc tttttaattg
     2341 ttaaaaagat aaaaatatat ttgatttaac agaaaaagag tgcctcataa actaaaaagt
     2401 tcattttgag acacttcctt aatattaata aattaattgg cttaaaatta ctgattgata
     2461 attataaagt acctctgtta aaggagtaaa ttctgaaccg attccaaatc ttaattctgt
     2521 aaacgcctct aaataatctg ggtcacatac atcttcttgt gttaaatctt gttttaccat
     2581 ttcagtagca agataaattg ctactgatgg tagaaaagca tccattggca taggatatcc
     2641 accaagtcta tttgacatgc caaaagcctt agccttttca cttatcatgt cgtttatttt
     2701 atcataattt tgagcatctt tttcagatat ttttagaccc ataacactag gatatgtttg
     2761 tattggtgat ggattgcttt gctctgcaac tatatacttt aattctaaag ccttagtcaa
     2821 tataacttca tccatatact catttacacc aaatacattt atatcttttc catatttttt
     2881 aacttgtttt tcaatatctt catttaaaaa ctgcttaact ttgtttttgt cttcttcagt
     2941 atttatattt ggagtattaa cttgtacaaa tggcaatcct atatttttgc aagtctcttt
     3001 aatcatttct aatcttttgg ctatattaac atctttcaaa tcatctgtag aggcataatg
     3061 aataaaagct tttgctccca tttcttttga acgttcagct aatacttttc ctctttcttc
     3121 tgcactaacc cctagattca catcaacaaa ttggcttaat tggtttttat catctcccat
     3181 aggggcagaa atagttatta tttctggacg cttttccttt accttttgta aagcaggtaa
     3241 aagccctgct tggtcagttg aaactacaat agcctgaact tctttatcgt cagccaactt
     3301 tactatctta ttaatagcac tatctatatt agaagtaaaa ttctctggca atacaacatg
     3361 ctttatagtt tgtttaactt tagtttgacc atctttgtct ttatcaattt tattctcttc
     3421 ctcatattct tttgccatct cttccaccat attatattgt actttatttt cagataatgg
     3481 ttgagttacc actgcaactt taaaatcatc tataattttc tctttatctt tcttgcctac
     3541 aagtaaacta caacctgtaa gtccaataat taaacatatg gatagcataa atgctgttat
     3601 ttttctaagc attaattaaa acctcctaaa tttgtacatt cttatcacta ttactaattt
     3661 tatcatactt caaagaaaaa ttatattata aaaaattata tacatgctat tataatccaa
     3721 tctaaaaagt actatgggta gattaggttt agattaaacc tacccatagt actaaaaatt
     3781 aatatattat aaaattaaat taattacaaa ttattatgct acttgtttgt tgctttttat
     3841 aaagttacca actattccac ccaatatagc tggtattacc cagttaaagc ccaaacctgc
     3901 aagtggcaag ctttgtataa atggaacagc tcctgtcatt ccatttatag ctgataataa
     3961 actaatcact aatgtaacat atgctgcacc tttaaaagca ttatcattct ttatatgttt
     4021 accagccaac tccataacaa ctattgctaa taaaacagga tatatagttt gtaggattgg
     4081 aactgatatg gctattatag aatcaacacc taaatttgat ataagcatac tagctacaca
     4141 tatacctata accagttgtt tataactcgc cttacttatt ccttcaaaat aagttgatat
     4201 tgatgctgtt aaacctgtag aagtagtcag acaggcaagt gccacaatta cacctaaaat
     4261 tacctttcct acttgaccat ataacaatat actagttatt tcaactaata aagatgcttg
     4321 aggtatacta gtatcatata aagttgaaac tgttgcacct aaataagtaa gaccaccata
     4381 tactactgct agaaatacac aggctacaaa accagcttta atagtcattc ctatttggtc
     4441 tttatctgat gtatatcctt tagctattat agacatcaac attatagttg ccatagatgc
     4501 tgcacctaga gcgtccattg tttgataacc ttgtgatata ccttcaccaa atagattttt
     4561 atctatcata tgctcaggac tcataggtcc tgctggagaa attataccct ttactattaa
     4621 aacaaataat actaataata acgctggagt taaatactta cctattatgt ctataacctt
     4681 agaagaccta atagtaaatg ctaaagttag cccaaagaag attattgaaa atacagcttt
     4741 agctactgga ccatggtctc caaatatagg cataataccc atttcatatg ttgttgcgca
     4801 agttcttggt attacaagaa gtgctaaaca tgctagagca gctacactca ttactcttgc
     4861 taacccttta ccagctctcc taagtacatc atccatgctt cccttacatc ttgctgttgc
     4921 tataataaca agcattgcta taccagcatc tgcaacaaca aatccaataa gaggaattaa
     4981 ccagtctttg ccggattcca tccctaaaaa tggaggaaac ataagatttc ctgcaccaaa
     5041 gaacatagaa aataaagcaa aaccaactat aaaaatatct ctcatctgct tactcacact
     5101 aaattacccc ctttgaaaat attttgaata ttaagataat cttactttat tttcagaaaa
     5161 atgtcaatct ggtaaaaatt cacacattgt taacgttttc ccaatttatt ttatgaatat
     5221 ttttttcatt ttatgataat tcccatcaat ttcgttaaat caattgcttg tgacacatca
     5281 aaaattgctc ctctaatatc atctatacca atctcaattc cctcaatatt attagtagta
     5341 aaatctatgc cagaaagttt agttccatta aagtttgctt tttttaaatt tgtatactca
     5401 aatactagat tgtcaccttt tacttcttga aatacagaat tttcaaaatt tgaatctaag
     5461 atagaaacta tcttaaattt agagaatgaa aagttagaat acttacctaa aacatccttg
     5521 aacaaaacgt ttttaagtat acaatcatca aatctaactc ctatcaattt actattttta
     5581 aattcaactc tgtatatact tcctccatca aaaaatgtat ttgataaatt gcagttttca
     5641 aataccacat caagtaaatc aatctttttt aaattacaat tttcaaaaga cacatttcta
     5701 aatatacaag attcaaagct aactcttaca gaatctaaat cacttataac ttcattttct
     5761 ataattttat taaatatttt ttcatcatta aatatatctt caagtatatc ttcaagattt
     5821 tcaataattt ctaattctcc tgtaaattta ggtttttgca ctttaataat tttagtcatt
     5881 ttcccctcca ctataaatta tatt
//
LOCUS       DAEQAF010000150         5779 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.154, whole genome shotgun sequence.
ACCESSION   DAEQAF010000150 DAEQAF010000000
VERSION     DAEQAF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5779
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.154"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            1..1066
                     /locus_tag="KRN00_003454"
                     /pseudo
     CDS             1..1066
                     /locus_tag="KRN00_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1193..2362
                     /locus_tag="KRN00_003455"
     CDS             1193..2362
                     /locus_tag="KRN00_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBH1829278.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKAIKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(2525..3067)
                     /locus_tag="KRN00_003456"
     CDS             complement(2525..3067)
                     /locus_tag="KRN00_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBH1829279.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(3215..3499)
                     /locus_tag="KRN00_003457"
     CDS             complement(3215..3499)
                     /locus_tag="KRN00_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBH1829280.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(3562..4326)
                     /locus_tag="KRN00_003458"
     CDS             complement(3562..4326)
                     /locus_tag="KRN00_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBH1829281.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPGLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(4608..4874)
                     /locus_tag="KRN00_003459"
     CDS             complement(4608..4874)
                     /locus_tag="KRN00_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBH1829282.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(4916..5725)
                     /locus_tag="KRN00_003460"
     CDS             complement(4916..5725)
                     /locus_tag="KRN00_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829283.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
BASE COUNT         2076 a          766 c          822 g         2115 t
ORIGIN      
        1 tataagttta gactgtatcc aaataaaaag caacaagagt taattaacaa aacttttgga
       61 tgttgtagat ttgtatataa taagtatctt gctaaaagaa tagatgttta taaaaacaat
      121 aaagaaactt ttacttataa acagtgtagt tctgatttga ccaatttaaa aaaagaatta
      181 aaatggctta aagaacctga caaattttca ctacaaaacg ccttaaaaga tttagataat
      241 gcatataaaa aattctttaa agaaaaagca ggatttccta aatttaaatc aaagaaaatt
      301 aatagatttt catataaaac taactttaca aatggaaaca ttatgtattg tggtcaacat
      361 ataaaactac ctaaacttgg tatggttaag gtaagggata aacaagtacc taaagggaga
      421 atacttaatg ctactatatc taaagagcca agtggtagat attgaagcat ttgaaaatac
      481 taataatcag ataggtttag atttaggaat taaagaattt tgtatctcaa gttgtggaga
      541 atttatagaa aatcctaagt atcttaagaa gtcattaaac aaacttgcta aattacaaag
      601 agaattatcg agaaaaacaa tcggtagttt aaatagaaat aaagcaagat taaaagttgc
      661 aagatttcaa gaacatatag ctaatcaaag aaatgatttt ctacaaaaac tatctactaa
      721 attaataaaa gagaatgata ttatttgcat agaagattta caagtaaaga atatgattag
      781 aaatcgtaaa ctatctcgct taatttcaga tgtatcatgg tcagaattta ttcgtcaatt
      841 agaatacaag gctaattggt atggtagaca aattgtaaag gtaggtaaat tctttgcaag
      901 ttcacaaata tgcaataaat gtgggtataa aaacgaggaa gtgaaggact taaatataag
      961 agaatggatt tgtcctagtt gtaatgaaac tcacgataga gatataaatg caagtataaa
     1021 tatattaaaa gaagaattaa gactaataac aattcaaaat aaataactta tgtaagaacc
     1081 gtaggaacta cggggatagc ctgtggagaa ttagtaagac atattttagt atgcaaaatt
     1141 ctgtgaagca ggaaccctgt gactttagtc atgggaggtt cagggtagaa agataaatga
     1201 actttgtaaa gatgaagttg tagagttttg caatagaata aaaggtaaag tggaaagtgt
     1261 tgcaataagt ggagtatttg ctccagtaaa taaacaacaa gaagaagaag ttgcaaaatg
     1321 ggttagagaa attttagggg atattcctat atctttatca aatgaaatag gtaatatagg
     1381 tatattagaa agagaaaatg gagctatttt aaattctgca ttgtctcaag taggtaaagc
     1441 tgtatcttta ggatttgaaa aagcacttaa agacttaggt atagatgctc aaatatattt
     1501 cagtcaaaat gatggaacat taatgaattt agagtataca atgaaatacc caatttttac
     1561 aattggatgt ggaataacaa attctataag aggagcttcc ttcttatcaa aagtaaaaaa
     1621 tgcaatagta ttagatgttg gtggaactac aagcgacttg ggtgtactat ataatggatt
     1681 ccctagagaa tcatctattc cagttacaat tggaggagta catacaaact ttagaatgcc
     1741 agatgtttta actattggtc ttgctggtgg tacatgtgta aaaggcgaaa aagataatat
     1801 aaagataggt cctgaaagtg tgggatatag aataactgaa gatgcaataa tatttggtgg
     1861 agacactcta actttatcag atgttgttac aaaattagat atggcgtttg aagatagaaa
     1921 aagcaatgtt gaaaacttag ataaagagta ttgtaatgag gtatataaga aggttatttt
     1981 aaaattagaa gatgctgtag accaaatgaa gactagtcaa gatgatgttg aattggtttt
     2041 aactggtgga ggaagtataa ttgttcctga aaaactaaaa ggcataagca atgttataag
     2101 acctcctcat tatactgctg caaatgctat tggtgcagct ttaggacaaa taagtggaga
     2161 tgtagaaaaa gtatacagtt tagataaaat gtcgagagaa gatgccatag aagatgcaaa
     2221 aaaagaggct gtaaataaag ctataaaagc tggtgctaaa gaagatacta tagaagtatt
     2281 aaatatagaa gatgttccac ttgcatacct tcctggtaat gcacttctta taaaagtaaa
     2341 agttgttggt gatttaattt aaagaataaa tataagtatt tccagaatta tataaatatt
     2401 tctggactca tttttaaact tattttatca ataaaaacag cataactttt gactatattc
     2461 ttataagttt ccaaacagcc gatatatacc tattttttga ggtttatcgg ctgtttgtta
     2521 tcttttatcg cattccaact atttttctta ccgtatttgc tgtacgaatt gtaatcttat
     2581 cacttacatt tgaactggca gtctttgacc accaatttgt ctttttataa tctttacgac
     2641 taaaagacca aaagatagca tttttataat gatatacttt ttcatactct tctttaggat
     2701 ttccaacctc atcataaaac tcgtcataag ataagtcagg aaacataaaa ataagattat
     2761 catatatttc tttgttgtta tctccccacc aattaggagc attatttagt atatctttta
     2821 actcctcttg tgaaataata aaaactggta tttccaattc aaactgtttt tttatcatta
     2881 atcttattgt atttgagata accttgctgt catctacatc acttaaaaag acaacattac
     2941 cactattaag gtatgtagaa acttctgaat aaccaagttc tacaaagctt gcttttaatt
     3001 cagacataat tatcttgttc ttaccactta tattgatacc tcttaataat gcgatataac
     3061 ttttcatata ataatttcac ctctaaacat tcacattttt ctatgtagta caaacttgaa
     3121 tttgcatctt ttataattct ttcaaaactt cttcatatgt aattttttta atataaaaaa
     3181 atcggtgctt aatttgtacc gatttttgtt tttcttagta aagaactcgt ttttttgctt
     3241 ctgctatagc tctagcagca ctttttgctt gcattctttt ttcttcttct tttttaaatt
     3301 catttattgt ttcatttaga ttcttatcat gttcattttt ttctttatct tcgttttctc
     3361 tgtatactaa tatataatct attattgatt cgtttattat ctgagatata cttttatttt
     3421 cattaattcc tattctctta acttccttaa gtagagtctc atcaatatga accgttgttt
     3481 gctttgtatt ttttgccacc ttaatcacct cttaaaaaaa attctaacat taaaattttt
     3541 tttagtcaat aaattttaat attaaaattc tttaaatgtt ttatttgatt ttctaaaatt
     3601 ttctattgta tttatcatct tattttttat attttcacct agtacagaag actttagtcc
     3661 aggattttcg atatggtcat aaattggttc taaaaattcg acttcgacag gaacagagtt
     3721 aattttacca ataggttggt atccttcata agtatctttt gaatttttta ttactagtgg
     3781 aacaataggg cattttgctt tatatgctat ctttaaagct ccacttctaa actccgaaac
     3841 caatgaattt ggttctttaa tccatgttaa atctccttct ggaaacactg ccatactttg
     3901 acctgtaagt atattttgag aggcttgggc tatactcttt ataccttcac gattgttttt
     3961 tctgtttaca tatacacatc ttagtaattt tgcccattct ttaaatatag gtatatttct
     4021 ccaaactggt tcatctgcaa ttacacatcc aattggtctt tctacacttg ctgttagtat
     4081 gaagctgtca agcatactag aatgatttac aacaaataga agtggttctt ttggcagtgt
     4141 ttccttacca attatattaa gctctatgtt cactatatct aaagattttt tagcttgttt
     4201 ttgcataaat tcaaattttt cctttaagct aaatttatca ggattctttt taattttaat
     4261 aagcctaggt atagaagatg taaaacctat aagttgatat gtagcaaatt ttaagtaatt
     4321 attcataaaa ttatctcctt aaaataaaat tatttattac tgtaaagatt ttaacataaa
     4381 ataaaattta agtctatttt aattcaattt tgtaacatat attttaaata gacagagatt
     4441 gagattttat atttccaatt ttagtaatca gattttatca ataaattact attctattaa
     4501 tttaattaaa taacctttaa atttaattat aaaaactgtt gcagaaattt ctacaacagt
     4561 ttaaaaaatt taccttacaa aaacttattt tataacaaga gagtatatta taaggctagt
     4621 acagcccatt ttttgcactg agaaattctt ttgccatcat caccttgttc tttgtcatat
     4681 gcaaattgat taagcatttc acatggaaat gtatcacata gaccacaatg tgtaaggttt
     4741 ttatcttcac aacaagattt tacaggacat tgttcacccc aaaatggttt ctcaatctct
     4801 gtacaacctt tacaattgac tttttccttg tatccacatt cataacataa aattccacat
     4861 cttgattcta tcattttaag tcactcctta aatataaatt ttatatgatt gtatatcaaa
     4921 atttatactt ttcattgtaa aaatcggaca aattttttat ataggttgtt ggattaacac
     4981 cacaaataga tttaaaatcg tttataaaat gagattggtc gtaataacca atatcttgtg
     5041 ctaaagttgc aaagggtatt ttattatttt gtatttcttg taatacaagg tttatacgaa
     5101 gtaatctaag gtatgattta acactcatac caagagaatt attaaaaatt ctatttaaat
     5161 gtcgttcact ataacaacta atttgtgaaa tgtttttaac agacataata gagttttgtt
     5221 ttctagcatt ttcaagaatt ggtatagtca tatctactat atttgatttc aataagtatg
     5281 ataagaataa catatctaat tgttctacta attcttttat agtacttgtt ctttcaaaaa
     5341 tggaattaac ctctaagcta aataatgtgt taaaatcttc aagtgaaatt tttaaatctg
     5401 tagattctct ttgagaaaga cctgtcaaat aatatactcc acctgggcga aactcaacga
     5461 atactctaaa aagtacattt tctatatcat tttttacaat agtagttttt gttgtggctc
     5521 cccagaatgc gctttctata ccttttttgt caaatttaaa tatcatacat ccactagcat
     5581 caggtattaa tgtaagattt tctttaatac ttgtatctgg aatagatatt gtatagtgtg
     5641 ctatatactg tcttaacaat ttatgtggca aaatatatgt atactgtttg caggtattta
     5701 aaatgttatt gattatttta ttcataagta tatcctcctg atatataaaa aataagtata
     5761 ctaatttatt ttttatata
//
LOCUS       DAEQAF010000151         5742 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.155, whole genome shotgun sequence.
ACCESSION   DAEQAF010000151 DAEQAF010000000
VERSION     DAEQAF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5742
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.155"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            52..2283
                     /gene="pflB"
                     /locus_tag="KRN00_003461"
     CDS             52..2283
                     /gene="pflB"
                     /locus_tag="KRN00_003461"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBH1829284.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPGALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            2443..3177
                     /gene="pflA"
                     /locus_tag="KRN00_003462"
     CDS             2443..3177
                     /gene="pflA"
                     /locus_tag="KRN00_003462"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBH1829285.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLNELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNTDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3299..4969)
                     /locus_tag="KRN00_003463"
     CDS             complement(3299..4969)
                     /locus_tag="KRN00_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBH1829286.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYKEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRMNYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTEETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
BASE COUNT         2030 a          818 c          825 g         2069 t
ORIGIN      
        1 attaatttta atagtattat ttatcattta aatctaagga ggaaatactt aatgaatgca
       61 tggcaaggat ttaaaacagg aagatggact aaagaaataa atgttagaga gtttatacaa
      121 ttaaactatt ctccatatga gggaaatgac tctttcttag ctggtgccac tgaaaatact
      181 aaaaaattat gggacgaagc aatggtccta tttaaaaaag aaagagaaaa tggtggtact
      241 ttagatgttg atacaaaaac tgtttctgga atagctgcat atgctccagg atatttagat
      301 aaagaattag aaacaatagt tgggttacaa acggatgccc ctttaaaaag agctgtcatg
      361 ccatatggtg gtataaagat ggttgaaaat tcatgcgaag cttttggata tgaattagac
      421 ccagaaataa aagatatatt tactaaatac agaaaaacac acaaccaagg agtttttgat
      481 gtttatactc cagaaatgag agctgctaga aaatctggta taataacagg tcttccagat
      541 gcttatggta gaggtagaat aattggtgac tacagaagag ttgctctata tggtgttgat
      601 gctttaatag aagataaaaa tgagcaaaag aaatcattag aagtttcttg catggatgag
      661 gaagttatca gattaagaga agaaataact gagcaaatat cagctttaaa tgaacttaaa
      721 aaaatggctg aatcttatgg atttgatata tcaaaaccag caactaactc aaaagaagct
      781 gtacaatggt tatactttgg ttatttaggt gctgttaaag accaaaatgg tgctgcaatg
      841 tctttaggta gaacatctac tttcttagat atatactttg aaagagattt aaaagctgga
      901 atcgtaacag aagaagaatt acaagagtat atggaccatt ttgttatgaa attaagaatg
      961 gttaagttcc taagaactcc tgattacaat aacctattct ctggagaccc aacttgggta
     1021 actgagtgta taggaggtat gggaatagat ggtagaacat tagttactaa aaactcattt
     1081 agaatgttaa atactctata tacattagga ccttctccag aaccaaactt aacagttcta
     1141 tggtcaacta aattacctca aggattcaaa gatttctgtt ctaaagtatc tatagataca
     1201 agttcagtac agtatgaaaa tgatgattta atgagagcat actggggaga tgactatggt
     1261 atagcttgtt gtgtatctgc aatgagaatt ggtaaacaaa tgcagttctt tggagctaga
     1321 gttaacttag ctaaaacttt attatacgct ataaatggtg gtgtagatga aaaatctggt
     1381 gttcaagttg gaccaagatt tgaacctata acttctgagt acttagatta tgatgaagtt
     1441 atgagtaaat ttgaaccatt cactgattgg ttagcaacat tatatgtaaa tactttaaat
     1501 gtaatacatt atatgcatga taaatattct tatgaagcat tagaaatggc attacatgat
     1561 agagatatat ttagaactat ggcttgtggt atggctgggt tatcagtttg tgcagactca
     1621 ttatctgcta taaaacatgc taaggttaaa actattagaa atgaacaagg aatagctgtt
     1681 gattttgaaa tagaaggaga ttatccaaaa tacggaaata atgatgatag agttgatagt
     1741 atagctgtag agttagttga aagctttatg aataaaataa gaaagaataa aacttataga
     1801 aattcttatc caactcaatc tatacttaca ataacttcaa atgttgttta tggtaagaaa
     1861 actggtaata caccagatgg tagaagagct ggtgctccat ttgctcctgg tgctaaccca
     1921 atgcatggta gagatactaa tggtgcttta gcttcattat cttcagttgc taaattacca
     1981 tatgaacatg ctcaagatgg tatatctaat actttctcta tagtacctgg tgctttagga
     2041 aaagatatga ctgaaagaat aaacaatctt tctgcaatga tggatggata cttcgctcaa
     2101 aatgctcatc acttaaatgt aaatgtattt gatagagcta ctttagaaga tgctatggaa
     2161 catccagaag aatatccaca attaactata agagtatctg gatatgcagt taacttcata
     2221 aaattaacta aagagcaaca attagatgtt ataaacagaa cattccacgg taaaatggct
     2281 tagtctttaa atttttatac tttaactaag attactactg tgtaaaaaat aaaaataaaa
     2341 ggctatctta tatttgaatt atttctggta taagatggcc ttttttagag aaatattata
     2401 actattgata aggttattaa aatatattgt gaggtgaact ctatgattaa gggaaagata
     2461 cattctatag aaacgtttgg tactgtagat ggaccaggaa taagatatat attatttttt
     2521 caggggtgtc ctcttagatg caaatactgt cataacaggg atacatggga tattaaatca
     2581 ggaaaagaat acacagttga tgaaataata acggatgctc ttaagtatac ttcttttatg
     2641 aagttttctg gtggaggtat aactgcctct ggtggtgaat ccactcttca accagaattt
     2701 ttaaatgaat tatttaaaaa agcaaaagaa aatgatatac acacttgctt ggatacatct
     2761 ggatttgtag atatagaaac tatagaccca gttttagata atactgattt ggttttactt
     2821 gatttaaaac atatggttga ggaaaaatct attgatttga ctggtgttgg tatggataag
     2881 gcattaaaac ttgctagaca cttagaatca agaaatattc ctgtatggat aagacatgtt
     2941 ttagttcctg gcattactga tgatatagat aatttagaaa aactaggtca atttgtagct
     3001 acattgaaaa atgtagaaag atttgaattg ctaccatacc attctatggg aatacacaaa
     3061 tgggaaagtt taggtatcga ttatgaacta aaagatgttc ctgatgccac taaggaagat
     3121 gtccaaaaag ctagtgaaat aatctctaaa tttggagtga aagtatataa tagttagtgt
     3181 agtatattaa tcctttatag aagacataac aaaatagggt aaagtgtaaa tttttaataa
     3241 acttcaaaac ttccactttg ccctattttt atatactata tatctcattt tatatacatc
     3301 actttgatag ttgaaattta taaaattcag aggcacttac aggtcttcca aataaaaaac
     3361 cctgaataat atctacccct aagcttttta ctatatcata ctcttcataa gactctattc
     3421 cctcaacaca aacttttaaa tttataatat gagctaattt aataatatat tcaagaaaag
     3481 tatattcata actattatat gtaatattct taacaaaact tctttcaatt tttattatat
     3541 taacagacag ttctttaagg taatttaaag atgaatatcc tgtaccaaag tcatctattg
     3601 caatatatac tcctataccc tttaaactaa taaatttatc atttagtaaa tttatatctg
     3661 gtatccaaca attctctgtt aattccaaaa ttaaaaattc aggtcttaat tgatactcta
     3721 ctaaacattc tactataaaa tctctaaaaa aatcttcctt taactgaata tacgatacat
     3781 ttacagatat tttaaagtct ggatttattt tatgccattc tttacactgt tttacagctt
     3841 cttttataat ccacttccca actggtataa ttaaattact ctgttctagt attggtataa
     3901 attcaacagg agatacttct ccataagtac tcgaatgcca tcttaaaagt acttctgccc
     3961 ctattacctc ttttgtaaca gcatttacct ggggttgaaa aaacaactca aaatcattaa
     4021 aattattttc aacgcactct cttagttttt gttgcattga aattaccttt agtttatttt
     4081 catagagctc ttgtgaaaaa aacttaattc tatttttacc actaattttt gctatatcca
     4141 atgcaatatc agcatgttta aataaatcta aataattatc tccatcttct ggatacatag
     4201 caacgcctgc agtcactgtg caatagtact tatttgattc aatttcatgc tgagtatttg
     4261 tatacatctg tatcttttca tatattttct ctatagtttc ttcagtacac atagggtaaa
     4321 aaaatgcaaa ttcatctcca tctaacctat acaatcttac atcttttgga agatattcta
     4381 atacttcagt agcaattgca cgcaatactt tgtcaccata agaatgtcca tatttttcat
     4441 ttatattttt aaaattatca atatccataa taaacatagc accattttta taaattttct
     4501 cttttataag ataattcatt ctatgttcaa attgttctct attccacgtt cctgtgatag
     4561 aatcaaattt atttttttca ccaatattct ttattctccc gactagaaat atagtttttg
     4621 ggtcatccga cacataaact ttacctctac aagaaatcca tactatttct ttatatttat
     4681 taatcaacct atattctaaa ttgtgctcac ctttttttcc atgtagtaat tcttgtatat
     4741 catctttcca tatttgaaca tcatccggat aaacaatttt actccaacaa ttgactaaat
     4801 cagattctat ctctttactt aagttaaatt catcaaaaat tgctgaagaa attttaaatt
     4861 tattcctatt tatatcccaa aaaaatatat aatcttctgt actttgagat aaaagttcaa
     4921 agaaaatttc tatatggtct aaacttaaag agttcgattc ttctctcatc ttttccccct
     4981 acaatattac tattagtgta gtttaatcaa caaaatatcc ttatttagat tatactattt
     5041 tactaatttt ttgtctcatc aaacacattt ccccaacttt agttatctta tcaaatctct
     5101 tactcttaac taagtttttt gagattcata aagtaatttt tctataatca ttactggtga
     5161 tttattttta cctgctaaaa caccatgtta aatcatttat taaatcattt tctcttaaaa
     5221 ttctattttt cgttatataa agagttatca gttctttatt ctataaaact tttctattac
     5281 tcttgaattt attttatttt tttcttcgcc tattctcttt ggatttggta ttgcttttct
     5341 atagattttg gcaaagaagt gtctcttcct ataatataag attttgatat ttcttcatca
     5401 tctataaatt ttttaatagg gattatatca ttttttatat ttatttatat aaatattttt
     5461 tgtttttaat tttttctatc ttcttatgta cttacattta atttattctt ttcagttaat
     5521 aaaataggta catttttagt acatgaaaat agagttgctt acagggtata taggattgat
     5581 gtactattta ctaatattac attttcaact gattcaaccc ctcttttact tacataattt
     5641 aagtatattt ttctggattt ttaaatttat gtactttaaa atggatatac ttattttcat
     5701 tgattttgta agaattaata aaaaatacga ttacactaca aa
//
LOCUS       DAEQAF010000152         5594 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.156, whole genome shotgun sequence.
ACCESSION   DAEQAF010000152 DAEQAF010000000
VERSION     DAEQAF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5594
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.156"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            122..238
                     /gene="rrf"
                     /locus_tag="KRN00_003464"
     rRNA            122..238
                     /gene="rrf"
                     /locus_tag="KRN00_003464"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(452..1636)
                     /locus_tag="KRN00_003465"
     CDS             complement(452..1636)
                     /locus_tag="KRN00_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBH1829287.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            2009..4360
                     /locus_tag="KRN00_003466"
     CDS             2009..4360
                     /locus_tag="KRN00_003466"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBH1829288.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDDLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4382..4921
                     /gene="nrdG"
                     /locus_tag="KRN00_003467"
     CDS             4382..4921
                     /gene="nrdG"
                     /locus_tag="KRN00_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBH1829289.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2173 a          631 c          902 g         1888 t
ORIGIN      
        1 tttgatgttc attcattaag atatatgtgt agtttttaga gtgctaactc taaagaaact
       61 agtattgcta ggttctataa acttattaaa aacttaatag aaatattaag cataaagatt
      121 atgtggttac aatagcagag aggatacacc tgttcccatt ccgaacacag aagttaagct
      181 ctctagcgct gatggtactt ggtgggaaac tgcctgggag agtaggacgt agccacgtaa
      241 tttttttgtt ataataaatt tagaatttaa cttatatagt ttaatttgat aatttgatga
      301 aaaaaataaa agacttactg atttttaaat ctataggtct tttatttttt atctaacatt
      361 taaattaagt tgttgaatat atcttatatt acttacctta tatattaatt atcattaata
      421 cattatatct aattactatt catctaaatt attatgccat tattttatat acaaattctt
      481 ttaatttatc taatccagat aagaaagtat tttcactgca agcataggat atacgaatat
      541 atttatccat accaaatgct atgccaggaa caactgcaac attatattct tctaaaaatt
      601 gattacaaaa ttctatagaa aaactatctt tatattcaaa tttctcagat actttagaaa
      661 gatctataaa tatatagaat gcgccatttg gattcacata tcctacatta tcaatagagt
      721 ctagttttga tttaattaaa tctcttcttg atttatatgt tttaaccata ttgtctatgt
      781 caattgagca atctttcaag gctccatagg ctatgtattg tgctgttaga cttgggtgag
      841 atataagatg tccttgtata gaactcattg ctttagcaat cgttttatta gatgcagtat
      901 atcctaatct taatccagtc attgcagctg acttagaaaa accatttata gttattgtta
      961 tatctttagc ttcttcgctt aatgatgcaa ttgatgtaaa ttcaccagtg tagcatattt
     1021 tttcatatat ttcatctgct aaaatatata ttttattttg tatgcataca tctactattt
     1081 ctattaattc atcttttgta taaacactac cagtaggatt tgaaggattg tttattacaa
     1141 gaatttttgt tttatctgtt atagattttt caagttcttc ttttgttaac ttaaatccat
     1201 tttctttttt agtatcaata aaaactggaa cagcattaac taacttaatc atttcaggat
     1261 aactaaccca ataaggcttt ggtaataaga cttcatctcc ttcgtctgtt aaagctagta
     1321 aagtatttgt tattgagttt tttgctccac ttgatacaac tatttcgtct attgaatagt
     1381 tacagttatt ttcttcaata agttttttac agatttcctc tctaagtatt tttaatcctg
     1441 gaactaaatc atatttagtg taatctttat ttaaagaatc aataccataa gattttgcgt
     1501 tattaggtac attaaaatcg ggttctccta tactaagatt tattacttta actccattac
     1561 tttccatttc tttaacttta gaactaatac ctattgtgta ggatggtgtt ataaagttta
     1621 gtctttttga taacataaaa tgcctccttt taaattatta tttatattat acgacaaatt
     1681 taaagaattt acataaggaa atttgtagat atatacatta atatatataa tagcctacac
     1741 tttttgccta aaattagtgt aaaaaaaaga gaaaaaaatt ttaactttca aagttgttag
     1801 aaacgctact gttcaaaata tccacatagt atttgcaatg atttgcgcaa gtttgactat
     1861 tatgtacaaa tttggtaatc ttaatatagc aattattaag ataatccctt taacttagtt
     1921 gaaggggatt tttttagact taacatacta catatagtgg tatggggatt aataaaatac
     1981 aatatatagt aacaggaggt ttttttaatt ggttgaattc gtaaaaaaaa gagatggaag
     2041 agtaattcca tttaatgaag atagaataac aagagctata tttttagcag caacgaatgt
     2101 tgcagaaaga gaaggaatag tacctgatta taaattatct gagcaattaa ctcaagaagt
     2161 aataaagttt ttaaatcata aatactcaga atcagttcca agtgttgaag atatacaaga
     2221 ttctgtagtt aaggttctta tagaaactgg ccatgcaaaa actagtgaag aatatataat
     2281 atacagaact gaaagaagta gaataagaaa ttcaaaaaca agattgatga aggcaataga
     2341 ggaaattacc tttgaagatg cagaagatgc tgatataaaa agagaaaatg caaatattaa
     2401 tggtaataca gcaatgggaa ctatgttaca atatggaagc actgtatcta aagaattttg
     2461 taaaacacat atattaaaac cagaacattc ttttgctcat gataatggag atatacacat
     2521 acatgatatg gattttttaa atatgggaac attaacttgt tgtcaaatag atgttaaaaa
     2581 actattcaat ggtggatttt caacaggaca tggcttttta agagagccac aagatataat
     2641 aagttatggt gcattagctg caattgctat acaaagcaat caaaacgatc aacatggagg
     2701 tcaaagtata ccatttttcg attatggatt ggctgaaggt gtatataaga catttaagaa
     2761 attctacata ggaaatttag ctaaagcatt gaagttattt aaaggaattg aaaataatga
     2821 tgtgataaag aacatagtat ataatacaga gaaagaaaca aatcaaaaag ttggtcttaa
     2881 gagagatgaa ttgtatctaa acttagaaaa agagaaatta atacagactt ttgatataga
     2941 tgatgaactt gtaaataaga tgcaaaactt tgcatttgaa gaatcgtata gagaaactga
     3001 taaaaaaaca tatcaatcta tggaagcatt tatacacaat ctaaacacaa tgcactctag
     3061 agcaggtgca caggtaccat tttcaagtgt aaacttcgga acagatactt ctgaagaagg
     3121 aagaatggta actaagaatc ttctattatc tcaagaaaga ggtttaggta atggagagac
     3181 accaattttt ccaattttaa tatttaaggt caaagaaggc ataaatttaa atcctgaaga
     3241 ccctaattat gatttattta aattatcatg cagagtatca gctaaaagac tattccctaa
     3301 ttttagtttt ttagatgcgc cttttaatgc aaaatattat aaaaaaggtg aaccagatac
     3361 agaggctaca tatatgggtt gtagaacaag agtacttagt aatgtgtgtg gttcagaaac
     3421 agttagtggt agaggaaaca tatcttttac tacagtaaat ttaccaagat tgggtataaa
     3481 acatggtatt ataaataatg aaaaggctaa tttagatggt ttctttgaag aattagatga
     3541 gaaaataaac ttaattatag aacaattatt ggagcgcctt gaggtacaag gaaataaaaa
     3601 gatgaagaat tttccattct taatggggca aggtgtatgg aaaggttctg atgatttagg
     3661 accagaagat acactaaaag aagtaataaa acaaggaaca ttgacaattg gatttatagg
     3721 tttagcagag tgccttattg ctcttatagg taaacatcat ggagaaagta aagaagctca
     3781 agaattagga ttaaaaatag tgtcacatat gagacataaa atggatgaag caacggacaa
     3841 atataaatta aatttctcct taatgggtac tccagcagaa ggtctttcag gtaggtttac
     3901 taaaatagat aaaaaagttt atggagaaat taaaggtatc acagataaag aatattatac
     3961 taattcattc catgtaccag tttattacaa tataagtgca tatgataaaa ttgagataga
     4021 agctccatac catgaattga ctaatgcagg tcatataaca tatgtagagt tagatggaga
     4081 tccatctgat aatttagaag cttttgaaac tgttataaaa gctatgaaag atttgggtat
     4141 aggatatgga agtataaatc atcctgtaga tagagaccca atatgcggtt tttcaggtgt
     4201 aataacaagt aatatatgcc ctgtatgtgg aagaaatgaa gatgaaagtg acatcaaatt
     4261 cgaaagaata agaagaataa caggatactt agttggtaca gttgatagat ttaataatgc
     4321 taaaaaagca gaagtaagag atagagtaaa acatagatag ttttatttgg gggaataagt
     4381 tatgaaaata agaatgtcat ctactataag ttatgacagc atagttgatg gaccaggatt
     4441 aagaatggta atatggactc aaggatgtat tcataattgt aaagagtgcc ataatcctca
     4501 gacacatgat ttatgtggag gattttatat ggatacagaa gaaattataa ataaagtcaa
     4561 atcattgaaa ttacaaaaag gcattacgct atcaggagga gaaccatttt tacaaccaga
     4621 accattagaa gaaatagcaa gagaagctaa aataaatggg ttagatgtat ggtcatatac
     4681 tggatttacg tttgaacaac tgttagataa aaaaaataga gcgtatttta aaaatttaaa
     4741 tttactaaag caaattgata ttttagtgga tggaaaattt atagctgaaa aaaaagatat
     4801 aagcttaaag tttagagggt catcaaatca aaggataatt gatgttcaaa aaagtttgaa
     4861 atataaaaaa gtgtttttgg ttgagcaata tatgaaggat gatttatcta tagcagaata
     4921 aaatataaat aaacaggatt aaatatatgc atatatttaa tcctgtttat tttcatataa
     4981 tatttcaagc ttgtataatg taacaattaa accaaaagac tcattgtata tttgaaatta
     5041 agttttttat agtttatagg tgttttatgt ggattacgaa tgatatagta tcgatacatt
     5101 atttaataga ttcttatgcc aagaaacaat taatttatag aaatttttaa ttgttacaat
     5161 ataaatatct agataagtta taagatactg ataaataatt tataaagttt attaatctaa
     5221 tattgtgtgt gaatattaag tggtcaagta gtctaaaaat gaaaaagatt taaaaaagtg
     5281 ttttaactaa acacataagt gttaaattca tgtataagta taggttagat acataagaaa
     5341 taattatgta atatctatct ttgtaaaaaa atattaaatt ttgtaatttg tggataaata
     5401 tgtttataat gtggataata tttaatgtaa taagttaaag caatatgaat caactgttta
     5461 taatgtggat aatattataa atgtatgaat aattgcagta tttaaaaaca aaaaaagtta
     5521 aaaaagttgt tgactctaaa agaaaaagtt ggtatagtaa tacttgtcct caagaaaagg
     5581 gcaaacaaat aaag
//
LOCUS       DAEQAF010000153         5400 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.157, whole genome shotgun sequence.
ACCESSION   DAEQAF010000153 DAEQAF010000000
VERSION     DAEQAF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5400
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.157"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(420..620)
                     /locus_tag="KRN00_003468"
     CDS             complement(420..620)
                     /locus_tag="KRN00_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBH1829290.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            complement(845..1021)
                     /locus_tag="KRN00_003469"
     CDS             complement(845..1021)
                     /locus_tag="KRN00_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829291.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(1075..1164)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            complement(1344..1544)
                     /locus_tag="KRN00_003470"
     CDS             complement(1344..1544)
                     /locus_tag="KRN00_003470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829292.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(1546..1896)
                     /locus_tag="KRN00_003471"
     CDS             complement(1546..1896)
                     /locus_tag="KRN00_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBH1829293.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            2058..2247
                     /locus_tag="KRN00_003472"
                     /pseudo
     CDS             2058..2247
                     /locus_tag="KRN00_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2724..2894)
                     /locus_tag="KRN00_003473"
     CDS             complement(2724..2894)
                     /locus_tag="KRN00_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829294.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESRYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(3283..3771)
                     /locus_tag="KRN00_003474"
     CDS             complement(3283..3771)
                     /locus_tag="KRN00_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBH1829295.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTEGNIIWWTKKDGKITVNSGIGDEDPLAHKIENLGMPYN
                     GSYTLVSSNGSEEYLELNIIIDGEISKSGLDKLEEDYGSSIKIPNDKNMIITFLSNKS
                     DN"
     gene            4575..4949
                     /locus_tag="KRN00_003475"
     CDS             4575..4949
                     /locus_tag="KRN00_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1829296.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLVAKRYLARYIINSQSHYKIIDSKEYYTFKKKVLKSSKSIKIMRSLTT
                     THKNVSKEKLDLLDEYYRNLKE"
     gene            5054..5400
                     /locus_tag="KRN00_003476"
                     /pseudo
     CDS             5054..5400
                     /locus_tag="KRN00_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
BASE COUNT         2171 a          652 c          615 g         1962 t
ORIGIN      
        1 tcaaattaac ttattgtaga ttttttactt tttaactaat tttatattta ttatatttca
       61 gtgaaaaaat agaacattga aacatataga tatgttttaa ttgcttttta ttaacaaatt
      121 actaaaagta ttatatcaga attgaataca aaagaaagag tatgtattta tgagatagtt
      181 gaaaattttg atgtgccaca actaaaatta ttatattact atatattcta attaaaagag
      241 tacttgtagg tttaagtaca tactttataa atatattttt gtcagattta ttttataaaa
      301 agtatttaga ctaagtatta tttttaagta tttttttgtt gaagttattt tttccttttt
      361 tacaaaatgc gtaaataaaa aaaagactct taaaagagtc tttccgaaaa atctatatat
      421 tataatatag ttatattttc tgcttgagga cctctagcgc ctttaactat atcaaagctt
      481 actttttgac cttcttctaa tgatttaaat cctgaagttt gtatagctga gaaatgagca
      541 aatacgtcat ctccactttc cattgatata aatccaaatc ctttttcatt attaaaccat
      601 tttactattc cattattcat taaaaatact cctattaacc tatatcaaga tatacttgat
      661 ttacttgtgt attaccacaa atactattgt atcatagatt aacataaatg tctatttaat
      721 tataattttt agttaacatt tttatttatt cttaatatga aaataaattt aaacatttta
      781 tattaccaat atattaatgt aaatgtagat aaaactaaaa agggttttct agaaaaaaat
      841 ctgtctaatt atacttactt accaatacca tcacttgatg caagcaagat tccacaactt
      901 tttctccgta ctctaatata aaatcatcta actgtgtatc tataaaatca caataatcat
      961 atgaactacc aatataagca gttaacatat gtgtacattt atccatttta tctctaaaca
     1021 taatgtattt atccccctaa aaaactttca tgaaaaacaa aaagaaaata tctttttggc
     1081 aactggctga cataacttat tttataagcg ttagtcccta tagctttgcg tcactaaatt
     1141 tctctagttt tgccgattta gttttattct acagattaat aatacaatag aattagttat
     1201 tattcaacat atctagctga aaaattaata aatttatata tgaacgttaa attatctgaa
     1261 aaaataaaaa gcccctctgt caggagtgac ttaaaaattg aatttaagtt tgtatttaaa
     1321 acacattttt aataatgcaa aaactaatca aaaataaaca attcatcaat aggtgtatct
     1381 actatttttg atatatctat tgctaatttc aaagaaggat tatactttcc tgcttctaaa
     1441 cgcataatgg tttctcttct aactcctact ttttctgcta attgttcttg agttaattct
     1501 tttaattgtc tatatttttt taggttacaa gtgaatttag gcatattatt tttcctctaa
     1561 aatataaagt tttatagcat aaacatttaa agtgattgca tatgtaattg atagtaaaac
     1621 acacattaat tctatattcc tagacactat agtaatacac cataaaatga ataattctat
     1681 aatagcaagc tgtcctgtaa atgccatagc tgctttttca tcttgtacat acctttcatc
     1741 tgctttatca ccatttattt ttgctataat aaagtttgag aaaaaagcaa aaaatccaat
     1801 atatgtaagg tcagcaacat tgccagatga aaaatatcta agacttaaaa atccaaggaa
     1861 accacaaaaa cccataaaaa attttttctg aatcattttt tatcctcctt agtaatttta
     1921 aaagagatat atttatatct ttatgataca aatatatctc ttttatattc ttttgtcaat
     1981 agaaaatcag tattatacaa tatttgtact gcaccataat tgttagagca aaaatctact
     2041 gcttgagatg tttatgtatg actaaatatg attttaattt caaattaaaa gtagctaaat
     2101 tttatttgaa tagagaagga agagatattt taatagtaaa acaatatgga gtttataacc
     2161 attctcaagt tgaaagatgg gttaatatat taggagagtg tgcactaaaa ataaaaaaaa
     2221 ttttctatac tatatggttc aagttagatg ttataaacta tatgatgata actaaatata
     2281 gtgtacaata aatcgctaag tattttggaa taaacaatag cacagttata gcaacatgaa
     2341 aataaaaatt tttacatagt ggtgttgatg ccttttctaa aatgaaagga agaccataat
     2401 gaataaaaac aaaaacacta aagaaaaaat aaattaacaa gagaacaaga attagaatat
     2461 gaaaataaat ttttaaaaga tgagcttgag tttttaaaaa agatgtgtgt ctcagggaag
     2521 ccacattaaa aaacagtggt atcattatta atcaaaagaa agttagatgt attatcaaaa
     2581 aattagaact taaatgcata gcattttttc ataaatcaca taaatataac tcctataaag
     2641 gtataattgg aaaagtaaaa aataataaaa caaatagaag atttaaaaca tcaatagcat
     2701 atcagaaaat aacaaatgat atgctagaat ttataaaata tatctaatga taaaaatgga
     2761 aaatcaatta taaaaaaggc atatctcgat tcattttttg ttatatagtc aaataagaat
     2821 actatagatg aaagatacga ttttgcatat gtattaagta agtattctga tgtttttggt
     2881 tgatacacat gcaataaaga agttgtgttt gcagataaat tagcaaaact atagtataag
     2941 ttgcaacaat aaagaaaatg aaaattatca tactaaagca taaggcatgt tacaatttta
     3001 ttagatagga cattaacata cactaaagta ctttttatta taaagagtac ttattttttt
     3061 gaaattcatt aatgtataaa ctatcaagaa tattactcaa cataatttaa aaacaacttg
     3121 aataggtatt tttaaattat gtgatataat aaaaaataga agtgtatgcc aatacacttc
     3181 tgtagttata actaagcatt ctattcttga ggagtgcttt tttcattttt ataaccaact
     3241 ctttttactt taacaataat tatcagacct atatatttat ttttaattgt ctgatttatt
     3301 agataaaaaa gttattatca tatttttatc atttggtatt tttattgaac taccataatc
     3361 ttcttctaat ttatctagac cacttttact tatttctcca tctataatta tgtttaattc
     3421 taagtattct tcactaccat tagatgacac taaagtgtac gaaccattat aaggcatgcc
     3481 taaattttct attttatgtg ccaaagggtc ttcatcacca ataccagagt ttactgttat
     3541 ttttccatct tttttagtcc accatattat gtttccttca gtatattttg attcatctgc
     3601 atagtagcta agagacgcac tttttattgc acttatatca gcttcaagtt tagctatctt
     3661 tgctttttct atatttttaa ataatgctgg aagtgctact attgccaata ttcctattat
     3721 agcaattact actaataatt ccactagagt aaatcctttt ttatttttca tttatttccc
     3781 ctccatataa aattaataat atataaattt ttattttgtt gatttctact ttctatattt
     3841 taccatatat agacaaaaaa atcactttct atgacaaata tactattatt ttacaattta
     3901 tggaaatgat ttaaaatgac atttcttgtt agaaaagata taagaaatgg attaaaataa
     3961 agaaaactac agtcatatca atgtcaataa tattatttaa aagcagatga aaataaaaag
     4021 aggactcaga aaataatgtc tatttaatta tacttactta ccaataccat aacttgatat
     4081 aaacaagatt atactacatt tttttatgct ctagtataaa atcatctaac tgtgtatcta
     4141 taaaatcaaa ataattatat gaactatcag tataataagt caaaatatgt atacatgaat
     4201 acatatttta aaagatatat attattacat acctaaaaaa ctttcataaa aacaaaaata
     4261 aaatatgctt ttagtaactt gttaacataa cttataattt attttataag cattagccta
     4321 tatagctttg tgctactaaa tctctttgat tctaacgatt tagtgctatt ctacaactaa
     4381 aataatacaa tagagctatt tattgtttgg tagcattgtt tgtaaattaa acaaatttat
     4441 acatatgaat attattttac attcaaaaaa acagactaaa tatgtagaat atttggtaaa
     4501 acttacctct agtttttgtc ttaaaaagct cctattatta acttaagtta gaagaattaa
     4561 ggaagtgaca taaattgaaa gaagaaatat taatagaaaa attattaaga gcagaattaa
     4621 tagtaatgga gtatttatgg aaaaaagaca ctctaatgcc taaaaaagaa attgtaaaag
     4681 aaataaaaca gatttatgga tggcataaaa gtacaataaa aatactacta aaaaggctag
     4741 ttgctaaaag gtatttggct agatatatta taaattctca atctcattat aaaataatag
     4801 atagtaaaga atattatact tttaagaaaa aggtactaaa atctagtaaa agcataaaaa
     4861 taatgcgttc acttaccact acacataaaa atgtaagtaa agagaagtta gacctattag
     4921 atgagtatta tagaaactta aaagaatgat atagtaaaaa tcgaatgtaa ttatttacct
     4981 taattctttt gtttgtaaaa ctttattgat acagaattta acatatacat aaattggtaa
     5041 aggaatgtat actatgaaaa ttagtaaatt accagaagcg gaattaaaag ttatgagata
     5101 tatttgggaa tcagaaaagg tattaatatc aagagaaatc accaagtcta tggaacaaaa
     5161 atatgaatgg aaagatacaa ctatatttac agtattaaaa agattactaa agaagagagt
     5221 ttttagaagc ggagaaaata gataagtgta cacactataa tgtattagta aaaaaaaata
     5281 atatcagaga ttttaaacaa aagaattttt aaagaataca cataaaaatt caatattaag
     5341 tttaatgtca gcactatgta gtaaggatga tgaagtagat ggtgatattt taaatttatt
//
LOCUS       DAEQAF010000154         5390 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.158, whole genome shotgun sequence.
ACCESSION   DAEQAF010000154 DAEQAF010000000
VERSION     DAEQAF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5390
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.158"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            185..1021
                     /locus_tag="KRN00_003477"
     CDS             185..1021
                     /locus_tag="KRN00_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBH1829297.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1374..2951
                     /locus_tag="KRN00_003478"
     CDS             1374..2951
                     /locus_tag="KRN00_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBH1829298.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEHTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            2944..4128
                     /locus_tag="KRN00_003479"
     CDS             2944..4128
                     /locus_tag="KRN00_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBH1829299.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVIINNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGEESEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     IL"
     gene            4146..4745
                     /locus_tag="KRN00_003480"
     CDS             4146..4745
                     /locus_tag="KRN00_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1829300.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4769..5239
                     /locus_tag="KRN00_003481"
     CDS             4769..5239
                     /locus_tag="KRN00_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBH1829301.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEVLVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
BASE COUNT         2017 a          562 c         1032 g         1779 t
ORIGIN      
        1 tttcaatgaa aatatgataa aatatgacaa attaattgat gacaataaaa aatattttgt
       61 tattgtagta ttatagggta aattgcaaaa tatatacgaa agtaaaattt taaatattga
      121 cattaaatta aatatactat actatgtaag tgtgatgaga gaattttttt agaggggatt
      181 tatagtgaat ataaaaaaga tatttaataa caatgtagta gtaagctccc tagaagatgg
      241 cacagaaata attgtcactg gtgctggagt aggatttaag aaaaaagtag gcgatttgat
      301 agatgaaaat ttgatttcta agaaatattt tgttcaagac gatcaaaggg acaaatacaa
      361 tcaaatactt aataagacct ctattgaata ctttaaaatt tcagaagaaa ttatagaaaa
      421 ggctaatgaa gttttaaata ctcaagtgaa tgattcaata atattagcct taactagtca
      481 catagaattt gctgtccaaa gagaaaaaca aggtataaaa ttaccaaact taatattgaa
      541 tgagacaaaa caactttata gggaagaatt tgaatttgga ttatgggcaa ttgatgaaat
      601 tgaaaaaagg ataggaataa aattgcctga agatgaagca ggatatattg ctattcacat
      661 aatcaatggt ttggaaaatt ctcaaaaaga tgaaggtatt aatatactag agttttcaaa
      721 acaagttatt cagataattg aagaagtaca tggatttaaa ttggatgtaa attcattaaa
      781 ttatactaga cttataactc acttaaagtt ttttgttcaa aggattctcc gaaaagaaac
      841 ttacaatgat agtgatattg aagatatgta taagttagtg aataaaaatt acaataaacc
      901 taaagtgtgt actgaagaaa ttgcagcatt ggtattagac agatttgaat ataagattag
      961 taaagaagaa gaattatatt taatgattca cataaataaa ataacaaaca gtggttgtta
     1021 ggattgtaac tgataaagca ggcaaaacct aagtcattga gcttaactat tagattaagt
     1081 tttttgattt aggttttttt attagataca atcaaaatac agacagtgac ttttaggatt
     1141 gtaactggtt aagcaggcaa aacctaaatc attgaattta actattaggt taagtttttt
     1201 gatttaggtt tttttattag atacaatcaa atacagacag tggttgttag gattgtaact
     1261 ggttgagcag gcaaaaccta aatcattaaa cttaattatt aaattaagtt ttttgattta
     1321 ggtttttcta taaatttgat tatgttttta gataaaaata ggaggggaaa attatgaaaa
     1381 aaaataagtt aggtttatgg aacttcttcc aaatgttagg aaaaacgttt atgttcccaa
     1441 tagcactact tagtgtttct gggatgatgc taggacttgg ggcaggtttt acagacccta
     1501 agatgattga aatggttcca tttttaggga atgaatatgt taacttagtt ttaaacttca
     1561 tgttaacaat aggattattt gcatttaaca acttgggagc attatttgca atggcaattc
     1621 cactaggatt attaaaaaaa gaaaaagagt ttggtgcttt ttcaggatta gtaggattta
     1681 tagcaatgca tataggtaca aatttttatt taacaagagc tgatttgtta gtaccagcag
     1741 aacagatgtc aactaatggt caagctatga ttatgggtat acaaacatat aatacaagtg
     1801 ttttaggtgg tattgtagca ggattaattg tttatgcaat atatgataaa gttagtaatt
     1861 taaagatacc agaatcatta ggattctaca gtggaccaag attagttcca attgttagtt
     1921 taatagttat gagtatagtt ggattattaa tacctattgt ttggccacca tttttcaatg
     1981 cattccaaag tttaggaaga tggatttctt cagcaggacc attaggatat ttttcatatg
     2041 cagtggcaga aagagttaca attccatttg gactaaatca tcttgtaaca tctgtattcc
     2101 gttttacacc aataggtgga actgctgtta ttgatggaga aacgtacttt ggtacattga
     2161 acatgtttat ggcatatgta gaaaataatc agattatacc tcttgattta gctggtaaaa
     2221 tggaacaagg taaattgatg attcaatatg gattagctgg tgctgcattg gctatctacc
     2281 gtacagcaaa accagaaaat agaaaggcac ttaaaggact tttaatatca ggagtgttga
     2341 cagttattat aggtggtata agtgaaccaa tagagtttct attcttattc atatcaccag
     2401 cattatttgc tttccataca tttatgaatg gtctagcaaa catggtactt ccatacttag
     2461 gcgtgttaat gggattcaca ggagatttaa ttgcatttat aagttttggt gtgttaagag
     2521 gaacagctac aggatggcca atagcagtat tagtagcagt tttatatttt gcaatatact
     2581 attttgtatt taagtgggca attattaagt ttaatataaa gaccccagga cgtgaggata
     2641 aagaaataaa agtatctgaa ggaaatggtt cagatttcaa aaatttgtct acatataaag
     2701 gacaacaaat gatatctgct ttaggtggtc aatctaatat attatcacta gataattgtg
     2761 taactagatt gcgtttaaaa ctacaagatg tatcattaat aaatgaggat gcaattaaag
     2821 aggctggtgg tatagcagtt gttaaattag atgagcatac aatacaagta attataggaa
     2881 ctcaagtgta ttctttaaga aagcagatgg ataaagctat ggaaggtcat ttggaggcat
     2941 gtaatgatta attttgataa aaaagtagac cgattgggta catattgtac ccagtgggac
     3001 tatgtagaag atagatttgg taagaaggat ttgcttcctt ttacaatttc agatatggat
     3061 ttagagtttc catttgaaat aacagaggtg ttgcaggaaa ggttaaatca tagagttttg
     3121 ggatacagta gatggaaaca tgatgatttt agaaattcag ttacgaattg gtatattaaa
     3181 agatttaatt gtagcgttga tagtaactgg atatattata gtccaagtgt aatgtattca
     3241 attagcaaac ttattgagat gttaagtaat gaaggagatg gaatccttat aaatactcct
     3301 gcatacaatg ctttttatga tgtgataata aataacaatc gtaatattat aaagtcacat
     3361 cttgtaaata ggaatggatt ctattcaatt gattttaatg attttgagaa aaagtgtaaa
     3421 aaatctaaga tatttatttt atgtaatcct cacaatccaa ctggtagagt atggagtgag
     3481 ttagaacttg ttaagatgat aggaatttgt aagaataatg atgtcaagat aatatcagat
     3541 gatatacaca tggatattgt atatgacaat agaatgacac ctatcttaaa tgttgcaaag
     3601 gactatttag attctgtatt catttgtaca tcagcgtcta aatctttcaa tataccagca
     3661 ttgactgggt catatgtgat tataccaaat gaaggtatta gaaataaatt tgaaaatatc
     3721 actagatacc gtgattttgt aaattcgcca gcaattctag caatattagc tacaatggtc
     3781 tgttatgatg actgcgaata ttggttagat gaactattaa aataccttaa agagaatctt
     3841 aaatatacga ttgattatat aaaagataat ttagaaccat tgaaattggt catgccagaa
     3901 ggctgttact ttgcttggat agatttttcc gaacttaaaa taagtggtga gaaattccaa
     3961 aaattattga tggatattgg agaagttgct attatgtcgg ggtctgtata tggtgaagaa
     4021 agtgagtttt atttaaggtt aaatgtggca tgttcaagag aaaaacttga agatggttta
     4081 aataggatta aaaaaactat ggattatatt gcaaaaagaa ttttatagta ggaagggaga
     4141 tagttatggg atatttaaaa acaatggttg atgttatgac tactgaaatg aatgccataa
     4201 gatgtttaat agatgaggca ggaatagaat atgaaagtat agttagtgaa attgcaaatt
     4261 gtgaaggcaa agtaattttt atgggtgtag gaaaatctgc acatataggt aagaaattgg
     4321 cagctacatt tgctagtact ggtacaccta gcttttttgt acatgcaaca gaggcagtgc
     4381 atggagattt aggaatgatt gaaagtaagg atattacaat tttaatatca aatagtggaa
     4441 attctatgga agtggtaaac tgtataaaat atattaaagc aataggttct aagacaattg
     4501 catttacttc aaacagaaat tcagtactgg caaaagagtg tgattatgct ttaatatatc
     4561 ctgcaaagga tgaagcagac catttaaatc tagcaccaac aacatcatct acaattactt
     4621 tggttttagg agattctatt gcatgtgcat tatctaagag tagtaatttt ggttcttcag
     4681 atttttataa gtaccatcca ggaggaagtt taggtgagaa gttaaaaaca gctaacaatg
     4741 gataaaagca aaaaggagag tagtttttat gttcaaaatg tttaaaaaaa aatcaataaa
     4801 atcacccata tcaggaaaag taatagagtt atctaaaata caagatggtg tattttctca
     4861 aaaaattatg ggagagggtg tagctataga ttctacagga gacattgtat atgctccaat
     4921 caatggaaag atagtagtag tagcagagac taaacatgca tttgtaatag aattagaaaa
     4981 tgggatggaa cttcttattc atgttggttt agatactgta aatttaaaag gcgaaggttt
     5041 tgaggtattg gtgagtatgg gagaacaagt gaaggaagga acaccaatgt tgaaaattaa
     5101 ccgtcctttg attgaatcaa agggtatatc acttattact ccagttacaa taactaatca
     5161 ttcagagtac aatatgaata catgtaatgt aggcaatagt gttgaaggtg ggaaagatac
     5221 tgtaattgag tttaaataaa gaactaaaat acaaggttaa tatttataaa tacctataaa
     5281 cttatgtttt ataagattga ttgtatagat ttgttgtata aaaaagaact ctttaattat
     5341 aaattaagga gttctttttt attttgtaaa tattgtttag atttatatag
//
LOCUS       DAEQAF010000155         5350 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.159, whole genome shotgun sequence.
ACCESSION   DAEQAF010000155 DAEQAF010000000
VERSION     DAEQAF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5350
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.159"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            305..1831
                     /locus_tag="KRN00_003482"
     CDS             305..1831
                     /locus_tag="KRN00_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBH1829302.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            1859..2416
                     /locus_tag="KRN00_003483"
     CDS             1859..2416
                     /locus_tag="KRN00_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829303.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            2938..3981
                     /locus_tag="KRN00_003484"
     CDS             2938..3981
                     /locus_tag="KRN00_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829304.1"
                     /translation="MLKKWFGIVKKRQKSESVKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDLLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VESEKIGLNKFEGLDQNENYNLEKNVIEEKKVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            4092..5234
                     /locus_tag="KRN00_003485"
     CDS             4092..5234
                     /locus_tag="KRN00_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBH1829305.1"
                     /translation="MSEEKNPKENTLDEPKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYVFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
BASE COUNT         2261 a          442 c          943 g         1704 t
ORIGIN      
        1 agtaaactga ttgcataaaa atgattttta tataattata taaaatttaa gcagaagaat
       61 aaatttctaa cgaaattgga tatttcttct gtaaatacat attcaaaaaa agaattataa
      121 gagtttagtc agcagtcgtg taagtaataa ggactttata aatatataga aatataatga
      181 tattaatata accaagcgat ttttaattta gctttttatt aagcttattt tttatactat
      241 ttataataaa taaactccat gatgggaaaa ctattactat ttaatatgta aaggagtatt
      301 ttaaatgaat gaatcatatt ggtttttaaa ctcaagtcca aaagaatata acaaattagg
      361 tgaaaatata aaaacagatt gtcttatagt aggtggtgga ataactggat tgacaactgc
      421 atatttatta gcaaaagaag gtaaaaaagt agtgcttgtt gaggctgata aaataggata
      481 tggaacttct ggaaggaata ctggtaaggt aacttgtcag catgatatat tttactctaa
      541 gatagagaaa aaatatggat tagataaagc aaaatcatat tataatgcaa ataatgaagc
      601 tttaaattta gttgaacaaa taatagaaga aaacaatata aaatgtgatt ttaaaaggga
      661 aacttctttt gtatttacag aaaaagagga tactataaag aatattaaag atgaatatcg
      721 tacatgtaaa aaaataggaa taaattgtga gtatcatgaa actatagaaa atattccatt
      781 agatataaag ggggctatta gttttactaa tcaaggtcaa tttaacccaa agaagtatat
      841 tgatggattg gcaaaagcag cagtaaattt agggctaaaa atatatgaaa atacaccagt
      901 agtagacctt gaaaaaggaa aaatatgtag ggttaaaaca agagaagata atataataga
      961 agctgagaat gttataattt catctcatag tccatggtat gatggattga atttttattt
     1021 tgcaaaagaa tatgcagagc gtgcttattt aatggttgca gttttggaaa ataaattagc
     1081 agatggtatg tttataagta tagatgaccc atcaataact tttagacaat ataatgatgg
     1141 aagtgaaaat ttactgattt ttggaggagg agaccataaa gttggtcagg gaggaactga
     1201 gaaagaaata tttgatgatt tagagcatta tggtaaagaa gtctttaagg taaaagattt
     1261 taaggggaaa tggtctgctc aagataatat gagttttgac aatgttcctt atattggtta
     1321 tatcaacaaa agagaagaca atatttatgt agctacaggg ttctctaaat ggggaattac
     1381 taatggaact gctgctggaa taataataaa agatttaata ataaataata attctgatta
     1441 taaagatact tttaatccat ccagactagg tagctacttt tcaaaagatt ttataaagga
     1501 aaatgcaaac gtagcaataa attatgtaag tggaaaatta aaaataggta gtggagatat
     1561 gcctaaaaat aatggagaag gaaagattgt taatattgat ggaaaaagat atggtgtata
     1621 taaggatgat aatggagatt tttatattgt agacactaca tgtactcatt taggatgtga
     1681 acttaatttt aacagtgaag aaaaaacatg ggactgtcca tgtcatggtt ctagatttga
     1741 ctataaggga aatatacttg aaggaccagc tcttaagcca ttaaaacttt atggacatgg
     1801 tgataatgat gttaatccta agttattata aaattatttt taggaaggta aagtgtatat
     1861 gaataaactt ttaaagccaa taactatact attgtatata gtttatattt tatctgccgt
     1921 attttttgta gcaaacaaag aatatggaag tctaggtcta gtagcaatta gtttagttgg
     1981 tactttcatt ttgagtttta taaataagca aactgaaaga ttattgagta aagaattata
     2041 tataatgctt gctttattta taatgttttc atcattgtta ggtacttgtt ttaattttta
     2101 tgatataaat tattatgatg attttttgca tttatggtca ggtataatat cttgtattgt
     2161 ggctttttct ataattaaat acttttatac acaaagagag ataagtaaaa tgagtaaagt
     2221 gtttttagtt atatttttat ttatgtttag tatgggagta gcgagtttat gggaaatagg
     2281 tgaattttta atggatactt ttgttgggac tactacacag gccggagggt tagaagatac
     2341 tatgattgat atggtagatg ctttaatagg cacaattata actattcctt ttatagtaaa
     2401 aaaatctaat atatagtttt aaatttttta tattaattat aatggattta attaatcatg
     2461 ttgagtttca aggtctatat gattaattaa atccattttt gttatttata attattattg
     2521 aatatatttt tacatataag atataaggtg atagatagaa attgttggat tatgtaaata
     2581 attaatatat aataccatta tgggcaataa atacaaatca aatgataata tagtctattt
     2641 atgtaaatgt tatattgtat cctaagtata atagtaagtt ttttgatagt ggtgtagaaa
     2701 gtaaaaatct actagcctaa attgatgtat ggattagttt aggaacagta attgcatatc
     2761 ttaagtttga tgtcatgttg ggctactaga aataggtcat ctttttcact tgaatatctt
     2821 ttctttaaac atggggagta tcatatcaaa aacatatgaa aattaagtga tttatgagaa
     2881 cagtaatatt ttatatgata gtatagaata gtaataaagt attaggagga acattgagtg
     2941 ttaaaaaagt ggtttggtat tgtgaaaaaa agacaaaaaa gtgagtcagt aaaagaagaa
     3001 ggtgaagtaa tattaaaaaa cgaaaaaata ttatctgaag aaaagttgat agatgaagaa
     3061 ggagttgtag ttaatattga taatgaaata ttaactaaag tagaagtagt aaatgatgac
     3121 aatgaaatag aagaaaaaat aatagaagaa gatttgttaa ttagtgaaaa taccataaaa
     3181 ttagatgata aagaagcaat tattaatgat aaaaacatag aattatgtaa aaaagaagtt
     3241 caagttgaaa gtgaaaaaat aggtttaaat aagtttgaag gactggacca aaatgaaaat
     3301 tataatctag aaaaaaatgt tattgaagaa aaaaaagtaa gtgaatgttt gacagaagaa
     3361 gatttagagt acataaaaga aattaaaata aaaagaggaa aaagtataaa agctataaac
     3421 ttgtatacta aagaagagtg ggtttttgac actcatatac agtgtagtaa aaaactcaaa
     3481 gttccattag ggtacataag agaaaattta aaatatggat atatggatta ctttggagat
     3541 gcaataaatt atttaagtga agtattaaat atagatgaat actgcaaaag tgaatggagc
     3601 tatctcgata atagcaaatc tccatctgag atatttaata ttctaaacaa taaaatattt
     3661 agtataaggc tttctaatga aaaaagaaat gaaattttga caaatgataa aattgaagca
     3721 ttaaaaatga attatagatt tgaatgtatt gatgaagaat atgatgaata ttttaaaaaa
     3781 tataagtcta taatcaaaag aggtggaaag aaaaaagttg aattagtaaa taaaaaaggt
     3841 gacattttag aaatatttaa gtctttagaa gaatgtgcca tttatttgca aaaggaaaag
     3901 aatgaagtta tacaaatgtt aaaatatgga gatacaaaag taggaagaaa ctttataagg
     3961 tatagtttga gaagtattta atttcatttt aaattcataa gagtttcatt tctgattcac
     4021 acatttaata ttattttaat gtaaaataat aaaggtgaag tattgcacaa ttaaaattaa
     4081 ggagggtatt aatgtctgaa gaaaaaaatc caaaagaaaa tacattagat gaacctaaaa
     4141 attcagataa tgtaaattct aaaaaagatg atgtgtcaga tgaaaaaaat actgataaca
     4201 aagttaaaaa aagggaaata aagctaaaca acaaaacact taaagctatt gtagcaattg
     4261 ttgcagtagg agctatatgt ttaggtggag gctatgtttt tggcaaagaa gctggaagaa
     4321 aattgcctgc tacttcaaaa cactataata gcagtgaggt agtagctact attggggata
     4381 aaaaaataac aggtgaaatg ttaagaaaga gaatggagcc attattttat ttaaatgcaa
     4441 aaactactat gactgatgac gaaatacgtt catatgaatc aaatatgatt gaaactatga
     4501 ttacatctga tatattatcc tctgaagcag caaaagagaa aataagtata actaatgacc
     4561 aactagatgc tcagtataat aatttaatga gtagtataga atcagcaatg ggaatgacta
     4621 aagaagagtt tttaaaacag tttgatttga ctgaaaaata tataaaagat gatatgaaaa
     4681 aagagctagt agcatcaaaa tatttaaatg aaaaatcaaa agttactgat aaagaagcag
     4741 agaactatta caataaaaac aagagcaatt atttacaagt tagagcttca catattttaa
     4801 taaaaactgt tgatgataaa ggtaagcaag ttagtagtag caaaaaagct gaacttaaga
     4861 aagaagctga agaaatactt aaaaaagccc aagctgggga agattttgct actctagcta
     4921 aaaaatactc tgaagatagt agtgcagaat caggtggaga tttaggtttc tttggtaaag
     4981 gtcagatggt ggaatctttt gaaaaagcag cctttgcatt gaagaaggga gaggtatcta
     5041 acaaacttgt agaaagtgat tatggatatc atataattaa gaaaactgat gaaaaatatc
     5101 agccatttga agaggtaaaa tcagatttag taagtagttt aacatcagaa aaacaaaacc
     5161 tacttataca aaatctaaaa gaaaaatata atgttaaaat tacagataaa tatcaaatga
     5221 aagctaaaga atagataaag tcaatttatt aaaaaaaaga aaaattaact gtatggataa
     5281 aagctatttt tactctcaat atagagagta taaaatagct tttattattt tgcaataaaa
     5341 tctatttata
//
LOCUS       DAEQAF010000156         5330 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.160, whole genome shotgun sequence.
ACCESSION   DAEQAF010000156 DAEQAF010000000
VERSION     DAEQAF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5330)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5330)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5330
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.160"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            434..898
                     /locus_tag="KRN00_003486"
     CDS             434..898
                     /locus_tag="KRN00_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1829306.1"
                     /translation="MNLNKVKFTEEHAIVVTNWKYEGKYSIYNLSPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMRIGKEIISLGLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(1165..1809)
                     /locus_tag="KRN00_003487"
     CDS             complement(1165..1809)
                     /locus_tag="KRN00_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829307.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(1739..3028)
                     /locus_tag="KRN00_003488"
     CDS             complement(1739..3028)
                     /locus_tag="KRN00_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829308.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDDILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGNIIIQNFNQIMINRIVISLGALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            complement(3025..3897)
                     /locus_tag="KRN00_003489"
     CDS             complement(3025..3897)
                     /locus_tag="KRN00_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1829309.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            complement(4427..4918)
                     /locus_tag="KRN00_003490"
     CDS             complement(4427..4918)
                     /locus_tag="KRN00_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBH1829310.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMDIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASDDGLAVIF
                     FIM"
BASE COUNT         1925 a          778 c          595 g         2032 t
ORIGIN      
        1 aactactaga atactaattt agtagttatt gtatctctaa agtttaagca tggatagata
       61 tacatttgat aatttgccta taatttacct actacttgga gtattggagc aaatacaata
      121 tattaataat aagttcctaa agccaataaa ttaactaata cacataaaga tattgatgtt
      181 gattatacaa ctataagaaa cagatttaac agaatttaat caagctaaga aattatatat
      241 atcgtgatgt ttttgaatta gaaggtaatt caaaattagt ttatagtctt ctgtgaatcc
      301 aataaaaagt acagggtaca agaattgtta gtaaaatttt taaagatttt atggataaat
      361 ataaatagtt ttacttattg tctaaaactt taaaatacca ttaattacct taaatatttt
      421 aataggagga catatgaatt taaataaagt taaatttact gaagaacatg ctattgtagt
      481 tactaattgg aaatatgaag gtaaatattc aatatacaat ctatctccat gggaggaaat
      541 taaaaagaag aatttttcac tagcaaaaga agataaaaga aaaaatttta taagttttat
      601 aaatgacaat aaagaattga taggttttat aaacttatta gatgaaggaa gctctgtatt
      661 ctttggtatt ggtatgaaac cgaattattg tggaatgaga attggtaaag aaataattag
      721 cctaggatta caagaatgta gaaataaata tagtactaaa ccaattgtat taaatgtaag
      781 aacctggaac atgagagctg taaaatgtta tgagtctcaa ggatttaaaa tagttgagac
      841 taaggtacaa aaaacgcatt taggagatgg agaatttttt gttatgaggt atcaatagtt
      901 tataacaata gtcttattgt taatacaaca attaaaataa aaaaatacat atgtgtaggt
      961 catagcaata agtgtctttg aaatataaat ttgagagctt ttgataaaat tttgtataca
     1021 tatatatttt atactacgga tatataaatc tatctacata cataaagaga ttgtaagtag
     1081 gtttgtgtat ataaaaatag atttatattt cataaatgta ccttttattt gtattacctt
     1141 tattttatct aagctctcat tttattatct aatcttcctt tttactggtt ttattaagag
     1201 agatgcaatt atcaacacaa cacttccaag tatcagccaa tatttctcat caaaactacc
     1261 ttgactcata gacattataa aaaattttcc aacatacttg cctttagtca tcatatttaa
     1321 aattaaatat cctatagata tcatataacc tatgattgta ttattaaata aatttgagaa
     1381 aaacattcct aaacttccta taaacatagc tgatgcgaaa cttccaataa tatactcaac
     1441 tactggaaaa ttacatccaa gatatattaa aacatttaca aaacctatga ttaataccac
     1501 tatacctata attgacatca gtatcctaat taattgtaca ataacttgag ataatgcttt
     1561 tgaagatact atctcatcaa tttcttttga ttgctctagc gaaaatacag gtaccaacat
     1621 tactatccct attattgcaa cataattttc taaacatata gctgttgaaa ttctgtctaa
     1681 attagctact ccttgtatta gaggaatcat acatagcaat ataattgaac atattaaatt
     1741 agttaaagtg cttaatttga agttttcttt tattagaact aaacagtttt gaaaactttg
     1801 cccaaacatc aagattcccc cttctttttt gctcatataa gaatatagct aacaaaacaa
     1861 gcaccaatgc tcccaagctt atcacaattc tattaatcat aatttgattg aagttttgta
     1921 taataatatt cccatttaat acactattat gtcttatcat tagccccatt gttgaataat
     1981 cacctttgag tcctgtagaa tttatactgt aaagccacca aattaattgc acaataattg
     2041 ctactggtgt atctgttaat atagtaatac tcattcctac agctgtaact atcataagag
     2101 ttggtagtat ccaccataat gtatatttta taaatgctaa gttatcaata gatatacctt
     2161 tatctttagc aaagaaaatc aaaggaagta aatctttcat acctaaaatt aatacaggca
     2221 atatcatcat aaagacaagt gcaaaatatc ttgataaaac tattttgcat gaagatactt
     2281 gttttgaata aataatctct ctcattcttg aacgcttatc tttaagtgac ataaaaactg
     2341 ccacaaatac tggaaatata cttaaaacta tacctatata atcgcaaaaa attcttgcat
     2401 acccattact aactttatct ttttgtattg tatagttgta attcttcata gcttcatcat
     2461 aggtaactgg aactactcca aatctttgta acttgtcaaa agcatatgca gaccctcctc
     2521 ctaaaatgtc gtctactctt tgcattattt cttcaaatct ttcaagagat actttagaat
     2581 aatctatttt tatactttca tcagttttcc aaagtgaatt tatttcgcta atacttttac
     2641 cagttatttc ttctatatat ttttctatgg tcttcgtttt attttggtct aattttatat
     2701 acttaactac ccctgttgga tacgttgtat atgtgttttt ttgatattct ctaattaggt
     2761 ttatagttgc atttggaatg actttttctg ttttcataga ttctttttga ccatatggat
     2821 attgattgtg tacagagtaa tattcctcaa tattctctac tttttgtgga gcaactaatg
     2881 gatttccatc attaggaata tttttactta catcatttga aactgaactt ccaagttgag
     2941 aaatatagaa aaaaactaaa actacaataa aaatataata taccatactc tttaatatat
     3001 ttttacattc ttttataaat agattcatat attatctcct cccattataa gcatatagcc
     3061 atcttcaata gttggattac aatttactgc tgtctcaaaa ggtttatcat ctgatataat
     3121 cctaagtata gcctttccac catgagtcaa cattcctata actataaatc tactttttat
     3181 attttcaatg tcttttttat ctacttcaat actatatact ttcccttcag ctagttttgc
     3241 taatgcttct gttgagccat tgtatatgac ttttccacta ttcaatatag ctacgttttc
     3301 acatgtagct tctatatctc caacaatatg tgtagataaa ataacgattc tatcatttgc
     3361 aatttcgcat agtaaatttc taaatcttat acgttcttct gggtcaagac ctgctgtcgg
     3421 ctcatctact attaaaactc tgggattatg aattaatgct tgtgctatcc caagccttct
     3481 attcatacct ccagataaag attttacttt cacattttga taattagtaa ggtttacttt
     3541 gcttaataac tttgctataa tttttcttct ttttcttagt ggtatatccg ataaaactgc
     3601 taaataatcc attgctttat atactgtcat gttaggatac attgaaaagt cttgtggcaa
     3661 ataaccaacc atatttctaa tttccttagt attctcaata ggaactccac acatatgtat
     3721 tgaaccttct gtttttgata ataaagtggc taaaattctc ataaatgtgg tttttcctgc
     3781 tccatttctt cctaaaagac caaacatacc actgtcgatt tcaagattta tattatcaag
     3841 agcttgtttt ttcccaaatc ttttactaag attggatact gctattttca tttccatata
     3901 taaatacacc cccagaaata attttataga attttatttt tataaatttt tactgtattt
     3961 tcataataaa ttctaaaact taagatatta tttataaatt tctaaatttt ttctaaagat
     4021 tttaattttt ctgtttttaa ttaaattaaa gtatccttgt ttctgaaatt ttttaagttt
     4081 atgaagttat aatttaatat atatttattt tatttgtgag tctattttta tatataatga
     4141 aaaatgtgat aagtatccaa aagaattact ggatataata agatagggta tttagccttt
     4201 taagataaat aaaaatatct gcaactatat attgcaaaaa tttaaaacta atttatatat
     4261 gctaatataa atatttataa agacataaga caaatttgcc tacagattta aatttaactt
     4321 atatatttta aaaggctaat ataatatgta ttttcttcta tacaatcaaa aggcttcata
     4381 tctaagatat gtgatgacac taatattcac aattttttag taattatcac attataaaaa
     4441 atattacagc tagtccatca tcagatgctt cttgtataaa ctttttaagc tcaattagat
     4501 ttgcccatac atattcaaaa aaatcatctt cactctcatc attcataaca ggataaatat
     4561 tattttctaa catctcatta atattaaatc tttttctaaa tgcttgttct tccaaactgt
     4621 tcattgcttt tgatagtttt tttacatcat ttgctgtaat caacatgaca ggaaattctc
     4681 catcaatgtc cataagtatg tttccactta gtactaattt gctaaatata ttatcatcat
     4741 ctccaccaaa aggacaacct gtcaaagtaa agtgaatggc atgccatgct ttatcaatat
     4801 tgatagtact attttcgttg gcatcttcaa aaacaaaatc ttgtaagttt tcttctgctt
     4861 gctgtaattt aaaaacattc tcttcactta ttttagtata acatcctatc atccccataa
     4921 ttacattcct cctaagtagc gtttttttaa ttgtaactta taattaaact tagttacaat
     4981 aaaatatatt gagaaaagta ttatttcatc ttaaatttaa atacctatat tatcaactaa
     5041 aattctgtgt ttatagcgta agtattatta ttttttccta aaaattaaat gaatcagaag
     5101 ttctataggc aatattgact ataaataaga actattactt tttaaaaaaa atttaagaaa
     5161 ttatactgta gaatcatgct ctacttatta gcttcaaata aaaaataaat catgttctca
     5221 aattaaataa taaataacaa taaatttaaa ttttaaacta taagagtttc tgaagtgtta
     5281 ataagcatac caataattat atgtgtaaga atttgattta atagatatga
//
LOCUS       DAEQAF010000157         5164 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.161, whole genome shotgun sequence.
ACCESSION   DAEQAF010000157 DAEQAF010000000
VERSION     DAEQAF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5164
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.161"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     misc_binding    198..460
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            536..3202
                     /locus_tag="KRN00_003491"
     CDS             536..3202
                     /locus_tag="KRN00_003491"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBH1829311.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            3627..4337
                     /gene="rgaR"
                     /locus_tag="KRN00_003492"
     CDS             3627..4337
                     /gene="rgaR"
                     /locus_tag="KRN00_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBH1829312.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNTITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         2080 a          508 c          893 g         1683 t
ORIGIN      
        1 aattaatgag aaagcattaa aattaaaata aaataatctt gcaattattg acattataag
       61 acagaataac tgtaaaaaca tattttaaaa tataacaact atataaaaga gaatagacat
      121 aattaagaaa attcagaaaa aataaaataa aaataattga caaagagaat aatatttgta
      181 tataataata tgtaatatta aagactgaga agaagaggag taagtaaata ctactaaaag
      241 agaggaaaat tcactggctg taagattttc taagtataag atttactgaa tgtagctttg
      301 gagtttctaa actgaactat aagtaagttt agacggttag aaccgttaaa ttctttgaga
      361 gtcaaagttg ataaaataac attaaccaat aatttaatta tatgttaatg tattttaagc
      421 tttggaatta aggtggtaac gcgagctctt cgtccttttt aaagaggatg aagagctctt
      481 ttttatttct aaagatattt aaaaaattta tttataaaat acaggaggca ggacaatgga
      541 aaatacgaat ttatcaaaaa cttataaccc aaaagatttt gaggctaggc tatataaaaa
      601 atggatggat gaagggtatt ttaaatctaa accaaatcca gataaaaaac catttacaat
      661 aatgatgcca ccaccaaata taacagggca attgcatatg ggacacgctc ttgaccatac
      721 acttcaagat atattaatca gatggaaacg tatggatgga tatgaagctt tttggcttcc
      781 aggaactgac catgcttcta tagcaacaga agttaaagtt gttgaaagaa taaaaaaaca
      841 agaaggcaag acaaagtatg aaataggtag agaagaattt ttaaagagag cctgggaatg
      901 gaaagatgaa tttggaggaa aaatatctaa tcagcttaaa caactaggtg attcttgtga
      961 ttgggataaa gaaagattta ctatggatga agggtgtaat gaagcagtta tagaattttt
     1021 tgtaagccta tatgaaaaag gtcacatata cagaggaaat agaataataa actggtgccc
     1081 agattgcaaa actactttat cagatgcaga agttgaacat gaagaacacg acggaaactt
     1141 ttatcatata aagtacccac taaaagatag tgaagacttt ttagaaatag ctacaactag
     1201 acctgagaca atgataggag atactggtat agcagtaaat ccagaagatg atagatataa
     1261 acatttaata ggaaaaacag caatacttcc attagtagga agagaacttc caatagttgc
     1321 agatagttat gttgatttag agtttggaac tggtgcagtt aagatgactc cagcacatga
     1381 ccctaatgat tttgaagtag gattaagaca taatcttgag cagttaaata ctatgaatga
     1441 agatggaact atgaatgaag tttgtggaaa atatgaaggt atggatagat ttgagtgtag
     1501 aaaagctatc gtagcagact taaaagaaca aggttaccta attaagataa aagagcataa
     1561 tcataatgta ggaacttgtt atagatgcca tacagtagtt gagcctagat tatcagagca
     1621 atggtttgtt aagatggaag aacttgcaaa accagctata gatattctta aaaaaggaga
     1681 attagaattt gttccagata aatttgataa aacttattta caatggctag aaaatataag
     1741 agattggtgt atatcaagac aattatggtg gggtcatcaa ataccagctt attattgtca
     1801 agagtgtgga gaaatagtag ttgctagaaa aatgccagat aagtgtccta aatgtggaag
     1861 cactcatttt aaacaagatg aagatgcctt ggatacttgg ttcagttctg cattatggcc
     1921 tttctctact ttaggatggc caaataagac tgaagcttta gattattatt atccaacaag
     1981 tgtacttgtt acaggatacg atataatatt cttctgggta gttagaatgg catttgcagg
     2041 tatgttctgt atgaatgaaa agccatttga ccatgttttg gttcatggat tagtaagaga
     2101 ttctcaaggt agaaaaatga gtaaatcttt aggaaatggt atcgacccat tggagataat
     2161 cgagcaatat ggagctgatg ccctaagatt tacattaaca actggaaatt ccccaggaaa
     2221 tgatatgaga ttctatatgg aaagagtaga atttgctaga aactttgcaa ataaattgtg
     2281 gaatgcatca agatttgtat ttatgaatat tgatgaagat ataattaaaa acatgactag
     2341 agaaagtgtt aaagaggact taactctagc tgataaatgg ataatatcaa gagcaaataa
     2401 tattgtaaaa gaagcaacta ataacatgga taagtttgat ttaggaatag cacttcaaaa
     2461 gatatacgat tttacttggt cagaatactg tgactggtat attgaaatgg ttaaacctag
     2521 attatatgga gaagatgcaa atgctaaatc tgcagcatta tatacattaa cttatgttct
     2581 tgaaaaaata ttaaaattat tacatccata catgccattt ataacagagg aaatatatac
     2641 tcatcttcct actgttgaag gatgtataat agtatctgaa tggccaaaat ataatgaaga
     2701 agataacatg gctgaagaag aagatatgat gaacttattg atggaaggta taagaagtat
     2761 aagaaatgtg agagcagaaa tgaatgtacc accttctaag aaagctaaat tgataataat
     2821 cccaagtgaa gaaaaaatag aagctattga gcttggtaaa gactatttta taactttagc
     2881 atctgcttca aatgtagaga tagcaaaaga taaatctaat gttccagaag atgcagttgg
     2941 agtagttatt gatggtgttg aaatatttat acctcttaat gaattagttg attttgaaaa
     3001 agaaattgag agattatcta aagaaaagaa aaagttagaa ggcgaaataa agagagttaa
     3061 tggaaagctt gcaaatcaag gtttcttagc aaaagctcct gaaagtttaa ttgaagaaga
     3121 aaaagcaaaa aaagaaaaat ttgaagagat gattaaatct gttgaggaaa gattaacaaa
     3181 tttagaatct aaaataaaat aaatataaga attagtaaaa acatacaaaa agtatatatt
     3241 ctatactttt tgtatgtttt tctttatata tatacaaata tgatgttata attctttaca
     3301 gatgtgttat atttttattt tatgttgtga atatatgaat tttatgtctt aaaatttata
     3361 agcaataaaa atttgatata ttatgatgtt taatataggg taataaatac atattatatt
     3421 tattttacta tattttttta cataatatat ctagaaaagt ataggaattt atcgtaattt
     3481 aagtttaaat attaaagaga atttctataa gtagtttaat cgacaattta aatttataaa
     3541 gaaatttaaa tttgaaagct agtgagtaca gtttggaaat tgaaataaag taaactaaat
     3601 gatattttag atttggaggt gatattatgt tcagggtagt tatatgtgat gacgaaaaaa
     3661 tacaaagaag catactaaaa gagtttacag aaaaactttt gtctgaaaga tgtctaaatt
     3721 atcaaatact ggaattttcc tgtggagaag atttaatatc caaataccca gaaaaaattg
     3781 atattatatt tttagatatc caaatgaaag atatcaatgg aattgaggtg gctaaaaaaa
     3841 taagaaagtt tgatgaaaaa gtagaaatca tatttacaac agctttttca gagtatgccc
     3901 cccaaggtta tgaggttcgt gcttatagat atttagtaaa gcctatagag tatagtaact
     3961 ttgcaatggg tgtaaatctt tgtattgata accttcaaag aaagaaggag cgttatatag
     4021 ttttaaatag taaaaaagga tttaatagaa tactgataga ttctatttta tatgttgaaa
     4081 ctgtaaagag agatttagtt gtacatacaa taggtagaga ttataaagct aatatgagca
     4141 tgaaacaagc agaaaaatta ctgtgtgaaa atggcttttt tagatgtcat acaagtttta
     4201 ttgttaattt aagaagaata gaagatctta gggataatac gattactatt aatgaacaat
     4261 ttatacctat aagtaagtat agacttaaag atttaaaagt agcattaaca agcttgttat
     4321 gtgatataat gtattaattt taaaaaggta attgaaaata tcgtaaaaaa gatttaatgt
     4381 catcacaggg ctattgattg aaactgtctt aatatataaa atgttattta tattaagaca
     4441 gttttattat gtaaaatagc agtttataga cttttaatat ggtttaatat gtatatgtag
     4501 agtttccatt ataatagcat gattattaat tagtagcttg attatcaata tactattatt
     4561 gatttttata tgcattatat gtatttttag aatatgatta cctttttaaa ataatgacta
     4621 tttataaaac tctatagata tttgtttcat ttagctatgc atactttaat taattatatt
     4681 aatatttaat ggagtacaat ataaatatta aagcgacatc ttatagttta ttgaacctat
     4741 agtaatgaat taataaatag tttaattcta tgaaaagatt tccttttatg caatttattt
     4801 attgaaatat gatataatat ataaaggtgt aagtattagt tgttaaaata atatttatat
     4861 tagtttttat gcatacttgg tataagtttt tcatatattg attaaaattg atgttgattt
     4921 attattttta gtattttttc accttttgat tcatactttg tagaatggtg tattttctaa
     4981 aactgattat aagacaagtt cgttcaaatt agcattttta tatcatataa ataattgttc
     5041 cccctaaata agatttagat gtatagtatt aaaatcaaaa agtataaaat aaaattgatg
     5101 cttaatcata gataaatatt aataaaatat acaaggggat tgtctaataa aaagataatc
     5161 tcct
//
LOCUS       DAEQAF010000158         5076 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.162, whole genome shotgun sequence.
ACCESSION   DAEQAF010000158 DAEQAF010000000
VERSION     DAEQAF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5076
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.162"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            960..1067
                     /locus_tag="KRN00_003493"
                     /pseudo
     CDS             960..1067
                     /locus_tag="KRN00_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1219..1881
                     /locus_tag="KRN00_003494"
     CDS             1219..1881
                     /locus_tag="KRN00_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1829313.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            1890..4397
                     /locus_tag="KRN00_003495"
     CDS             1890..4397
                     /locus_tag="KRN00_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829314.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDAAN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQVMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNAFINKFMIKFFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IVTTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSIIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            4728..5072
                     /locus_tag="KRN00_003496"
     CDS             4728..5072
                     /locus_tag="KRN00_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829315.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKHLTVKGNEYTIINY
                     YMSNFSQYIIFAILLASMGFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
BASE COUNT         2229 a          457 c          769 g         1621 t
ORIGIN      
        1 aactatgcta aaatttaatt gaataaatta aaaatataat gaaagtttag ttttaattca
       61 tttatttaat aaacatttca agtaaaataa tgtttaaatc agaaatataa ataaatatta
      121 ttataatcgt tattaaagac caaaaatccc atcttagaag tttgtatcat atgaaacctt
      181 tatagattat gaaagcaata atatagtgta tgatatataa aataagttat aaaagtattt
      241 ttttagatat tcaaaaagac attgtaagtt atattaataa tatgggtatc aacgaatttt
      301 ggatataatg agtttttcaa cttaaagtta tgtaataatg aatgtaaaga atatttaatg
      361 aaatcatttt gttggttatg tctagctgaa tacaataatc ttttagataa agattttata
      421 tttgaagata ggtgtgaaaa aattaagaag atattaacat cagcagttta gaggcaaagc
      481 atgtaaagta aagtctgggt aactaaaagt agtaatttag attgtaacta ttgttataaa
      541 tatgaaaatg aggaaacagg aaatataagt taggatgtag aaaataggtt actaaataaa
      601 aagcttaatt atataatcaa agaaataggt atatactgta caatttcatg gtgaagaact
      661 tttcctaaat aaaaaggttg gtaaaagaga tataagaaat aaaattcaat tataagatat
      721 ggtatgataa ctaaaggcac tatatggagt gaataggcgg aagaattttt tgaaaattat
      781 aaaaatagtt tctgttgcta catatcaata agtatagata gagattgcaa aatccatagc
      841 aaaaatcgaa tttataaaaa tagtatagga ttatttgatt aaagaatagc tacgtacact
      901 cgtgacttta gtcatgagtt agtagctaaa atagtcagca tatagggaaa cctatatgta
      961 gagaatggat ttgtcctagt tgtaatgaaa ctcacgatag agatataaat gcaagtataa
     1021 atatattaaa agaaggatta agactaataa caattcaaaa taaataacgt atgtaagaac
     1081 cgtaggaact acggggatag cctgtggaga attagtaaga catattttag tatgcaaaat
     1141 tctatgaagt aggaaccctg tgactttagt catgggaggt tcagaagtgt aaataacatg
     1201 taagacaagg agtaaattat gagtatttta gagataaaaa acctaaataa aatatatggt
     1261 aaatcggaaa cagaggtgaa agcgttaagt caaataaatc taaaaataaa tagtggagaa
     1321 tttgttgtga tagtaggtaa aagtggaagt gggaaaagta ctttactaca cataatggca
     1381 gggcttgaaa ctccaacaaa tggtgatgtg attattgata atataaatat atcatctctt
     1441 gatgaaaaga aaagatctgc attacgtaaa gaaaagttgg gattaatatt tcaatcatat
     1501 aatttgattc cagttttaac tgttgaagaa aatataaaac taccaactat aaatataaaa
     1561 aataaagatg aagcttatat taatgaattg atggagttac taggaataaa agatagaaga
     1621 atgtatttgc caaatcaatt atcaggtggg caacaacaaa gagtagcaat agcaagggct
     1681 cttgtaaata aaccatcaat tgtatttgct gatgaaccta ctggaaattt agacacaaag
     1741 acagagtcag atgtattaag tttattaaaa gaatctcaaa aaaaatataa tcagacaata
     1801 ataatgataa cacataatat agatataaca aaatatgctg atagagttat agaaatagaa
     1861 gatggattta taagagagta ggtagattta tgaaacttaa ttatattgta aaaaaatata
     1921 taatgggaaa taagaaaaat acattattaa taattgtaag tattgtaatt tcaacagcgt
     1981 tgtttttaat tatgaatata ataagtgaag atgcggcaaa cttaatgata aatcaagcta
     2041 aaaatgaatt tacattaaaa catgcacaat atatcaatcc aaaagacgaa gaaataaaat
     2101 atatagaaaa taacacaagt atagataaag ttggaaaatc aatgctttta ggaattagtg
     2161 atattggtaa aggtcaaaca ctacaaattc tatctcagga taaagttgct gaagaactaa
     2221 atgatattta cacactagaa aaaggtaaat taccagtagc tgaaaatgaa atcgctatag
     2281 attcatggta tattaaacaa aaaaagataa aaaaccctat aggaaaaagg ataacattag
     2341 attatagaag acaagggata gatcaagaag atttatatac tggggaaaaa gaatttaaaa
     2401 taactggtat cttaaatagt aatcctattt taaaagctca aggaacatca attggcctta
     2461 taagtaacga ttgtgctatc aagaatattc ctactaaaaa taaatatgat caagttatgt
     2521 ttacttttaa aaaggaaaaa aatatacaga gacaatcaca aaaacttatt aaaaatggaa
     2581 atttgaatga gaataacatt tattttaata atgaattatt aatagctata tctgatagta
     2641 tgaatttaaa aataccttat ataatagtta atatagtact agcactagca actatattat
     2701 taatttataa tattttttat atattagtat caaatagaat aaaggatttt gggatattta
     2761 gggctttagg gtttaatcca aatgatattt ttaaaataat gattttagaa gtatctatat
     2821 actctattat aagtatttct ataggtctaa ttttaggtgg gataatagct agtttatcaa
     2881 gggagtatgt tataggagta atatacaatg tcaactatat aaattctata aaaaaccaga
     2941 actatataaa cacatacata atttctatat tattaagttt aggaactata ataatatcag
     3001 tttcaaaacc tcttatgtta tcagttaaaa ctgatccaat gatttgtata agaagaaata
     3061 atgaaaaagt ggatataaaa caaaatgcct ttataaataa atttatgata aaatttttca
     3121 aagactatgg taacatagca tcaaaaaata tacaaagaaa taagaaacgt acaaatttat
     3181 ctatagcatc aatggtaatt atatttttct taatggcaac aatatacaca aagtctacta
     3241 gtaacttttt aagtgatggt gtattaaaat attggataca aggagattat ttattacata
     3301 atattgatat aagtactata cgttcaaata ataaaggtta tgataaaaat gtactacaag
     3361 agataaaggc aattgatggt gtaacaaaag taaactcata taggcataag tggtttaata
     3421 taaaaattga tgataaaagt ataaataaga actctgatta ttggaaaaaa aataaagata
     3481 atattgaagc tagatcagaa gtaaaagatg gaattaaggt atataataat tcttttgaat
     3541 ttttaggaat agaagataca gatatactag aggatttctt gataaatgga aaggaaaata
     3601 tagataaatt tagtaaacaa ccatatctgt atataacaaa gaaatccagt gattcactta
     3661 atataaaaaa aggagataga ataaaagtat actttgatat tatagattca aaaacaaaca
     3721 attttaccaa aacaatatct caagaattta tagtatgtgg aattgtaact acattaccag
     3781 taacctcaca agtgggagct gaatttggcg gagtaatatc aacaaatcaa tttaataagt
     3841 ttacaggaat atcatcttat gaaagatttg acatatggac gagtaaacta gccaatgata
     3901 aatatgttga aagtgagtta aacaaaataa cagaaaaaac aaataaagga attttaattc
     3961 catacaaagc tgaaacagct gaatatgaaa aaattgataa tcaaaaaaca ctaattatgg
     4021 tattagtaac tggaattata gttatattat ctttatttaa ctgttgcaat actatagtta
     4081 ctagtattaa tagcagaagt agggaatttg cactatttag aggaatagga atatcaaaac
     4141 atgaaataaa taaaattgtt aaattggaaa gttatatata tattatagta agcttttgta
     4201 tatctataat acctatttta attgtaagaa gtataataat aaaacctttt gaaagtatca
     4261 atttaataaa ttggaaattt ataggggcta ttatactaat agtatttatt ttagtatcta
     4321 taatcatgat aactacacta aaaacattga ataaaattca aaatgaaaat tttatggaag
     4381 aaataaagac tttatagtga acagcctata aattaaagag gttttatatg aatttaattg
     4441 caattatcga taatggtgta gatattgatt ttaaataatt tagaaataaa aataaaataa
     4501 gttatccaag ttatatgtat gatgtaatag gggtacaatg tatagcaaat ataaatattg
     4561 gcttaataaa actctactct taagtctact gtcgttttaa cacaagacta ataataagtg
     4621 taacctaaaa attattgata atacaataac cttgtttatg ataaataaca aatattaagt
     4681 gttgtaaaga tagtaagttt aaaaaaatat caaagatttc aatcacaatg tattgtttat
     4741 ctgtagtgtt agctatttat ggtatatatg tatttataaa ttgtactgaa tatatatata
     4801 ctatgctatc tacaaaacat ttaacagtca aaggaaatga atataccatt ataaattatt
     4861 atatgagtaa ctttagtcag tatataatat ttgctatttt acttgcatca atgggatttg
     4921 taatacaaaa gatagtgcat atgcatttca gtgagataga acttagtggt aactattcaa
     4981 caactgttag aaatataagt gatatctctt tagataatga taatgaaatg tttaatagag
     5041 gcaatattga aaatagtatt ttaaaaaaat aaataa
//
LOCUS       DAEQAF010000159         5020 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.163, whole genome shotgun sequence.
ACCESSION   DAEQAF010000159 DAEQAF010000000
VERSION     DAEQAF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5020
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.163"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            28..831
                     /locus_tag="KRN00_003497"
     CDS             28..831
                     /locus_tag="KRN00_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829316.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYANNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
     gene            843..1973
                     /locus_tag="KRN00_003498"
     CDS             843..1973
                     /locus_tag="KRN00_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1829317.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISKSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            1977..3386
                     /locus_tag="KRN00_003499"
     CDS             1977..3386
                     /locus_tag="KRN00_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829318.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYVIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKSEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            3597..4106
                     /locus_tag="KRN00_003500"
     CDS             3597..4106
                     /locus_tag="KRN00_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBH1829319.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
BASE COUNT         2090 a          422 c          860 g         1648 t
ORIGIN      
        1 aaataattat agaaagaaag gcacattatg gaaaaattga gagttattga aatgataaaa
       61 aataatccca atattatagc tacaatagat aatccaactg atgaaatgaa attgttagct
      121 attaaagaaa atgggcttgt actagaatat ataaataatc caaccagaga gatgcaagaa
      181 ctagcaatag ataataatat tagagcaatt aaatttatag ataatccaac agaagatatg
      241 atgataaaag cagtaaatga gggatggagt atactggatt atatcaagaa tccaactgat
      301 aaagttattg aaatggctat aaatcaagca ggatgggcaa ttaaatatgc taacaatcca
      361 agtgaagaat tacaactatt agcagtaaga aaaaattatg attcgataaa gtttataaaa
      421 caaccttatg aaagtgtaca agaggaggca gtgagaataa gttatgatgc cttgagatat
      481 atagattcac ctagttacaa tgcagaactt atagctataa aaaataatga agcagctatt
      541 agctttataa ctgatttaga taaaaataaa atgttggaat ttttaaaagt gaatatttta
      601 gtgattaagt acattctgaa aaaagtatct aaagatgaat tagagagtgt attaaaagaa
      661 gtattatcca aagaagatgt tgaggaaaag tatattagag attttttgaa ttgtagtgtt
      721 atagatagaa atagtgaaag tataccaata gataaaatta tgtttattta taaatatgga
      781 agtaagacag caaaaaaaat agctgtagat gagaaattaa agattatgta ggagagagaa
      841 aaatgaattt tatagacaca ttaaaaagcg ttgacttaat attatccact ggagaagtac
      901 ctttaatagt aggtgaaagt ggaataggaa aaacagcttt agcaaataag cttgccaaag
      961 aaaatgattg gagtttaatt gttattgatg gaaacttact taaagagggt gaaataggtg
     1021 gtcttccaac tatagaatct tatgtaggag ttaattctaa tggatataag actgaaaaga
     1081 aaacaacagt gtatgctgtt cataacaaat taagagaaat tgatgaagag atatctaaaa
     1141 gtaagacagt tcttttattt atagatgaga taaatcgttg tgagcataca gtacaacaag
     1201 aacttatgaa tttaatttta aatagagaaa ttaatggata taaactgcat gatgatgtaa
     1261 agattttagc agcaatgaat ccatcaagta aatatggttc agattttgat tatcaagtgg
     1321 tagatatgga tgcagcccaa gaaaataggt ttgtttggtt aaatatggag agtgaccata
     1381 cacaatggat aaaatgggca atagatgagg gtattgaaag aaaagttatc gagtttattt
     1441 ccacttttcc agaatatctg cataaaataa atgaagatga tgtaagagct actcctagaa
     1501 gttatgagag agtatctaaa atttataaag tttataaaga aaaaaataat tctattccta
     1561 gagcagtatt tttaaatgtt gtaaagggta atgtaggtaa agttattgca gaagaattta
     1621 taagttttat tgaatcaaac tctgaaccat taatatctta tgaagatgtt tttttaggag
     1681 aatctattga tgagtctatt gtagaaagag taaaaaatga gagtcataca agactttatc
     1741 tatcagctat gaacattcta aaagacttag aattaaatat taagaatgat aaatatgaat
     1801 caaaccacta tattaataga tttattgaat ttttaaaaat gtatcctgta gatttaatga
     1861 taggtattat gaaggatatt agaaacagtt atattgaagt atataaaaaa gctatagaaa
     1921 atgaagagtt tgtaaaatcg tattttgaat cttatagttt aataagggga taatgtatgg
     1981 aaaattattt tgataaacaa gcaaaagagc tttataataa agcaagtgaa attataaata
     2041 ctcattctat gctaaaggca aatcgtgcta atgagaaatt tgatatagat ataccacaag
     2101 attttaagta tgagtttttt agtcttgtag ataaagtgaa tttaagtctt atggaagaag
     2161 aagataattt ttatggatat tttttgtttc agatgtcaag agaaataaga tttgatataa
     2221 gtagtcctac aggtgtgaat tttaagggag ctaaatatgt tatatatttt aatccaataa
     2281 tctttttaac gcttgacata aagcaaatgg agactacaat taaacatgaa attcatcata
     2341 tattatctat gcatttgatg agagcaaagg agttaaaagg aaagtatagt acattagcaa
     2401 ttaatatggc aatggatata gtagtaaata aatttctaaa caatttacca ccatatgcaa
     2461 ctaccttaga gtgggtaaat ttaaaatatt ccttaaaact tgaaccatat gaaccttttg
     2521 aatattatgt agaaaagatt cagactgaat tagatttgat ggaagtggat gaagatggtg
     2581 aggaagatga tagtgataaa tatggagata tagaaattga ttatagcccc gaaagaactc
     2641 atgatatatg ggatgaatcc aatgagatag atgaaaatac ccttagagaa tttactgaaa
     2701 aatttattaa cagttctcaa aaaggtaaag ttcctgctta tttagaaagt atgatatcat
     2761 cacttaaaaa tagtaagggt gaattgccat ggaatttata tcttaataga ataatgggaa
     2821 cagttgaaaa taataaaaag aagactataa caagaagaaa tagaagacaa ccaaatcgtt
     2881 tagatttgag gggagaactt agaagtcata agtcagaaat agcagttgca cttgatgtaa
     2941 gtggaagtat tagtgatgaa gagtttaaac aagctattaa agaagttctt agtatagtga
     3001 aaaactataa tcatgaaatt acaattatag aatgtgataa tgaaattaga cgtgtatata
     3061 aagtgagaac tgaaaaagat ataaaagata gaattaggat aggtggaggt actagatttt
     3121 ctccagtctt tgagtatgct aataataaaa agattaattt gttagtctac tttactgatg
     3181 gtaaaggtga aaataaacta caagtaatac ctagagggta taaaatttta tgggttattt
     3241 ctggaagagg agataaaatt tcattaaaag aaccttatgg agcagttaaa aaacttacta
     3301 aggttaaaac aaatgatgaa atattagaaa taaatgatgt aagaaatgat gggtactcaa
     3361 tgaatagcca agcaccaatt ttataggtat tcacaggaga taagctgtat taatttattt
     3421 tgatatgctt gttataaaaa tctaaaaaat acattaatca atggttaatg tattttttaa
     3481 ttttaataat ataagtttta cttacattta agtcttaaaa tgtgttaaaa tataatatat
     3541 agcagatagt tttggcaagg tggatttagt tgtcaaaact atttttttta ttaaggatgg
     3601 tgatgttttt gtttaagatt gatgattata taatgtatgg tatgacagga gtctgcaaag
     3661 tcatggatat aacaaatgaa cgatttacaa atggaataaa aaaagagtat tatgtattga
     3721 gtcctattta ttctaataat acagtaataa aaattcctgt agataatgaa aaagtaccaa
     3781 tgagaaagtt actttctaaa attaatgtgc tttcattaat aaatgatatt cctaatatgg
     3841 atacatcatg gatagataat gaaaaattga gaagtgagca atttaaaaaa atactcagag
     3901 gtggtaaatg tgaagagtta ataaaattag taagaagtat agataataac agagagtatg
     3961 taaaatctat tggtaaaaaa acacatcaag cagatgataa tataatgaaa gaagctgaaa
     4021 ggttattaaa tgaagaattt gcaactattt tagatatttc tcctaatgaa gttagttcat
     4081 atatttcaag tcatatacct caataaagtg ttttagtatc ctttatttaa tctattttaa
     4141 gtattattta tgtatgctgg ttttggtaaa ataaaatata taattaaatt atataaaaaa
     4201 taatgatgat tgtattgaag aattacagaa tagtgcggag agcccactcc tttaggtgtg
     4261 agatggatat cacttaaaga tttaaattgt tattgtagat gtttttgtac tttttaatat
     4321 aaagcaagat taataagtgt attgtaagct ttaagtgaaa ttgatactat aatgagttac
     4381 ttagatttta aaatatataa tattataaaa aatcctttta ggttttgaat gaataagatg
     4441 gatactatgt tgaatagaat ccatcttatt taagttttat ttatgttgtt tatttgtaag
     4501 cattattttt gtacatgaaa acacagtgta aaaatatgct tagaattatg aagttttatt
     4561 aaaaacatat tcgacaaaat aagactaaaa atattcttaa acttataact aagataaata
     4621 ttgtatattt atagtgtagc ctgaaaaatt gtggatgtac gaaatttatt tagtatttta
     4681 ttgaaacaaa gtagaaaaag tactatagtt tatctttgaa tagattgtta ttttttagtg
     4741 aaaaagttat taggttaata cataaatata atagattata aatattttaa gcatgttaaa
     4801 aaagtagtta ttagagatat atagttacat tgcttataag atacttaaaa tgagagcatt
     4861 cacttatatt tagaaaatta agataaaaaa tcatttttat atagtaaagc atacctaaat
     4921 ttagaaaata attgaattta taaaattaat taaatacata aaaaagtatt caatcaactt
     4981 aacaaatttt tttaaattta atttgaattt tttattctat
//
LOCUS       DAEQAF010000160         4965 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.164, whole genome shotgun sequence.
ACCESSION   DAEQAF010000160 DAEQAF010000000
VERSION     DAEQAF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4965
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.164"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            688..4830
                     /locus_tag="KRN00_003501"
     CDS             688..4830
                     /locus_tag="KRN00_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBH1829320.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDITTGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDVVVESIPN
                     PNPTNNIATIDYSYTPVEGGIPNDFSVDSNPVPVEVISADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDLPASIINPEYSLDGGVTFQPWNGSLNIGTLEVGETK
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIPDVILNPEYSLDGGATFQPWN
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIVTLDAGEIRSIIIRGTVSQTAVGIIINTATISSPTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIVNTATVSSTTPDPNLNN
                     NTSTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVTFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVIILRGIIKSTCLDRLTNI
                     AEVTSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKDCCCNCCKNDF
                     WC"
BASE COUNT         1930 a          723 c          827 g         1485 t
ORIGIN      
        1 attcaaaatt atatataaaa ttcagaaaaa aattttagtt tacataataa aaataaagtc
       61 aactaaaatt attgatttta gattaaagta ccagattaag catttaagta gattttaagc
      121 ttgatttgat tagaaaggta caaactatca ccgaaaaaaa ttaaacccat ttaaaaagca
      181 atataaaagc ttgttatttt tgagaaaaat agaccctcta aactcaatta gattaaaaat
      241 aaaatacaga aaattatatc tctaaatatc ttaaataatt aagtttaaat tttacgatat
      301 tttgtttgat gatttataat ataaaagcat actcttaatc ttcaaaattt aaaaagagta
      361 aaaaataaca aaaaaatcac tgacatttca ctgacaaatt gtaattttgt tattataaat
      421 acattgaaaa tacttgatta ttgaaaaatg gcataaaata atacatttta tgccatttac
      481 tattatttga tagtttttaa cttatgacat aagatatttt ttaacatata caataaaata
      541 taaaaaaatt gatattgcaa ataaaaaaaa tacatattag atgttataga aaaaaagcgc
      601 acttataggc ttaaaatgtc acataaaaga gttttaaaga ataatatatt atgaacacaa
      661 attttgtaat cacaaaggag tgataatatg gcaacagtat caggacaaat agtttttgat
      721 agaaatagaa gtgctaccat tgattctgga gactcaggaa tagccaatat accagttgta
      781 ttacaagata taacaactgg agttagactt gtggttctca cagatgcatc aggaaattat
      841 gtttttacta atgttccaaa tggtaactat agaattgtag aagcttttgg aactacagga
      901 ggagtaccaa caccagggaa ttttgcaaca gcgatagtag gtccagttcc aattgcagaa
      961 atgccaccta ttagttctgt gacaaatcct cctattggtt caacaaactt agatggtaca
     1021 acacctaaca cactattaat aacagtagca ggttcagata taacaaatca aaatatatta
     1081 aatgggcctg tgatttatac acctatagag aatatattgg attcttgcgt atctgtatct
     1141 aatataaacc ttattacaga tgcagataac ggaacattcg gtttttttcc accaggtaca
     1201 ccaagtaata caggacctga aatagaacct tacccaaatg tgacgccaga ttttacgtat
     1261 gttgtaccag acccaactaa gtttacacct ttagatggag aatatacagt acaaaatatt
     1321 atgacaaatg caatgagtaa tgttatagga gcttggtggc gtattgctga ccatactaca
     1381 ggaaatgaaa caggaagaat gatggtggta aatggtttta atcctggagc tgtatttttt
     1441 aaatcaacag tacaagttac acctaacact aattatttat ttagcacttg gattttaaac
     1501 ctttttaagg taacaggata tccaccacca cagctaggtg taagaatatt tgaccaaaat
     1561 aataatatac tatatcaagc aacattagga gctcaaattc cagttaatac aaacgcacca
     1621 gaatggaaag aagtaggtac tgtgattaat tctcaaaata ataatcaact tacagtagaa
     1681 ttttttagtg aaggagaaag cgccattgga aatgactatg ctatagatga tgtttcttta
     1741 agagaaatag ctgttccaac ttttactcca ataaaaacaa gtaacacaga aactgctaat
     1801 gtaggtgata taatcacata tacagttaca ttagataata cttgtgatag ccctttaact
     1861 aatgtatttt ttagggattt aattccaaat ggtttagagt ttatacctgg aactgtaacg
     1921 gttgatggag tatctgtacc aggagtagac cccaatacag gtttcccact tccagatatt
     1981 ggaggaggaa caggggttga agtaactttt gatgttgtgg ttgaaagtat tcctaaccca
     2041 aatcctacta ataatatagc tactatagat tactcctata cacctgtaga aggcggtata
     2101 ccaaatgatt tttcagtaga ttctaatcca gttcctgttg aagtaatatc agcagatatt
     2161 gaagttacaa aattatctga acctactata gtgaatccag gagaggaatt aatatacact
     2221 ataaaagtag taaataatgg accattccca tctgagaatg tggttttaac agatgattta
     2281 ccagcttcta ttataaatcc agagtattca ttagatggag gagtaacttt tcaaccatgg
     2341 aatggaagtt taaatatagg gacattagaa gtaggagaga caaaagttat tataattagg
     2401 ggtattgtaa atccatcaac agtaggaatt ataacaaata cagctgtagt atcttcaact
     2461 acagcagacc caaaccttaa taataataca tctacaatag agacagaagt gaatttatta
     2521 gcagatattt tagtaatgaa aacagcagaa cctaattcag ctgttccagg tactttattg
     2581 agatatacta ttcaagtaga aaacttagga ccagcaaatg ctgaaaatgt aatattaaat
     2641 gatgatattc cagcttctat tataaatcca gaatattcat tggatggagg agcaagtttt
     2701 caaccatgga atggaagtct taatatagga actttaaact ctggaatttc attaacagtt
     2761 ttaattcaag gaacagttag tttaaattct tcagaatata tagtaaatac agcaacagtt
     2821 tcttcaacta cacctgaccc agatttaagc aacaatatat ctaccattat tacaccagtt
     2881 aacccacaag caggtatttc tattataaaa gtagctgacg aggatgtagc tgttccagga
     2941 gaagaatttg tatatacaat tgaaattttt aatgaaggac catctaatgc tacgaatgta
     3001 gttttaacag atgatatacc agatgttatt ttaaatccag aatattcatt ggatggagga
     3061 gcaactttcc aaccatggaa tggaagtctt aatataggta cagttgcacc agggcaatta
     3121 ataagaatta tcataaaggg attagtaagt tcaactgcta caggagatat tactaataca
     3181 gcagaagtaa gtgcagatgt accagaacca gttacggatt catcaacagt gacaactcct
     3241 atagttccat cagcagatat agaagtaata aaaactagca atatggatac agcagttcca
     3301 ggagaaactt tcagttatac tataacagtt acaaatttag gaccatctgc tgcacaaagt
     3361 atcgttttga cagatgatat accagatgtt attttaaatc cagagtattc attggatgga
     3421 ggagtaactt tccaaccatg gaatggaaat cttagtatag tcactttgga tgctggagaa
     3481 ataagaagta ttataataag aggaacagtg agccagacag cagtaggtat aattataaat
     3541 acagcaacaa taagttcacc tacacctgac ccaaatccag ataataatac ttcaacagat
     3601 gaaacagata taagtccatt agcagatatt tctgtgataa aaggcaacga accagttgct
     3661 ataccagggg gaagatttat ttatggaatt gaaattgcaa atgcaggacc atcttttgca
     3721 gagaacgtaa ctttaacaga taatatacca gcttctattt taaatccaga gtactcaata
     3781 gataatggag tgactttcca accatggaat ggaagcctta atataggtac tttagatgct
     3841 ggagagataa gaaatatcat aataagggga acagtaagtc aaacagcaat aggcacaatt
     3901 gtaaatacag caacagtaag ttcaactaca cctgacccaa atctaaataa caatacttca
     3961 acatcagaag cagaggtaag ttcatcagca gatatttctg tagtaaaacg aagcaatcag
     4021 actgttgttg taccaggaga tgtactagac tatacaattg aggtgagaaa tgcaggacct
     4081 tctactgctc agaacgtaac tttaacagat aatataccag cttctatttt aagtccagaa
     4141 tattcaatag ataatggagt gacttttcaa ccatggaatg gaagtcttag tataggcact
     4201 ttagatgctg gagagataag aaatattata ataaggggaa tagtaagtca aacagcaata
     4261 ggtacaatta taaatacagc aacagtaagt tcaactacac ctgacccaaa tccagataat
     4321 aatacttcaa catcagaaat agatataagt tcatcagcag atatttctgt aataaaatta
     4381 gcaaataaaa cagaagcatg tgtaggagag caaatagatt ttgtaatagt agtatcaaat
     4441 gcaggaccag aaaatgctca aaatgttact ttaatagata atgtttcaga taagcttaag
     4501 aaagcagtat tttcacttga tagaggtgta agtttccaac catggactgg aagtcttaat
     4561 ataggtacac taccagctgg aactttaaga gtgattatat taagaggaat tataaaatca
     4621 acatgtcttg atagattaac aaatattgca gaagttactt caacaacacc agattcaaac
     4681 cttaacaata atatatcaag agtgcaagta gaaataaaac aatgttgttg taatgattgc
     4741 tgttgtaaca actgtagtaa ttgttgttgc aatgattgtg gttgtaaaga ttgttgctgt
     4801 aattgttgta aaaatgactt ttggtgttga ttttataaaa taattttgta taccttaaat
     4861 taaactgaaa taaaaaataa attcacatat gagtaaaata ttttataaat attaataaat
     4921 tttctatctt tgatatggac cacattcgta atactagtta ttaaa
//
LOCUS       DAEQAF010000161         4741 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.165, whole genome shotgun sequence.
ACCESSION   DAEQAF010000161 DAEQAF010000000
VERSION     DAEQAF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.165"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            249..1388
                     /locus_tag="KRN00_003502"
     CDS             249..1388
                     /locus_tag="KRN00_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBH1829321.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKTIEDKNDLALESYYSSVIEGAFSTRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HTGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKDFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICNKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            1414..1602
                     /locus_tag="KRN00_003503"
     CDS             1414..1602
                     /locus_tag="KRN00_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829322.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            2386..4170
                     /locus_tag="KRN00_003504"
                     /pseudo
     CDS             2386..4170
                     /locus_tag="KRN00_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
BASE COUNT         2049 a          536 c          765 g         1391 t
ORIGIN      
        1 aatatataat cgagatattg ttaagacatt gtcgagatat tataatatgt aactaatgta
       61 ttataaataa tagttgcaaa cttcctgtga catatatttt aaatgcttat tcttaaattt
      121 ttgcattatt tattaaaatt tattatgctt taacgctaaa ttgagtttga taattataaa
      181 acaaataatc aaaaatagtg taaaaattaa tactttttgt taatattaat agataaagat
      241 aatctaaggt ggtgattaaa ctgacaatag aagaatacaa aaacaaatac tttactggaa
      301 ataaaatcgt actttctata aatagttttg acaataaaga actatactat catgaaactg
      361 aaaatatatt aaatttaata aatgaaatag ataaattaac atcaagtaag atatttaaaa
      421 caatagaaga taaaaatgat ttggcactag agtcttatta ttctagtgta atagaaggtg
      481 ctttttcaac tagaaagatt gcaaaatcta taattagagg aaagatgaaa ccaagtaata
      541 aaagtgaata tatgatttac aataatcata gagccttaga atatggatta gacaacttag
      601 ataaattata tagtcacaaa tttatatatg atttgcatca tatattgggc gaaaactgct
      661 tggattcaga agaatatgag tatagaactg aaaaagtata tgtatgtgat tcaaaaggtg
      721 agattataca tacagggctt gaacctttga agatatatga ctttatgagt aaattaatag
      781 attttatgga aaatagcaaa gtaagtaatt taattaaaag tgctataatt catttttact
      841 ttgtatatgt tcatcctttt agtgatggta atggaagaac atcaagagcc ttatcatatc
      901 tatatttgat tgataaagga tatgatactt tcaaggattt ttcaatatca tatatgatat
      961 ctaaaaacag aactaagtat tataaggcta tacttgatgt agaaaacaaa ggaaataatt
     1021 taactgtatt tatagaattt atgctcaagt ctataataca atctattaat gagatgcgta
     1081 atatgcatga tagaaaatct ttagaaagta tattaaaaga agaattgttt gaaaatgaca
     1141 taactctatc agcaacagaa gaacatatat taaaatatat ttgcaataaa gataactatt
     1201 ctatgacatt agaaaattat ataaaaaaga ataaaagtag atacttaaag gctggaataa
     1261 aggaaattga attagttgac cagttgatgg aagtgtttaa taatcttgaa gagatagaga
     1321 ttttgtctaa agaaaaaaat atatataaag ttaatgataa gtacttaaaa atgcttgata
     1381 tagactaatt tagataatct ggagagggaa tatatgaata ataagaaaaa ggcatttttg
     1441 atttctgggg ctataaacgt aatttcatta attattgttt tttcattgtt tcattataat
     1501 attatagaaa atagtacaca aaatatgata ataactgtaa tcttaatttt tatttttgaa
     1561 atgataaaaa taaaaatcat agagaaatac tataaactat aaacaagaaa tatcttttct
     1621 aagagcatat tgtacaatat gctcttaatt tagttatata gatttaatat aaataatgta
     1681 ttttttgtag atgatttatg taagatttat gaccaatttg tgtatgattt gtgttattta
     1741 atcatgacaa tattatattg taaaaaataa atttaataaa aaatgacttg gaatttatat
     1801 tctaggtctt ttttatataa aaatttaata agtttcaaat gttggtaact ttgacagtag
     1861 aaaacgtcta ttgagataac gaggattcta attgaggggg agagatatta gcacttaaag
     1921 tagtatatgc aacagatata atctttacaa aagtaatttg aattaaaatg taaatataaa
     1981 gaataattaa aaaaatatcg taattatttg tttttcatat ggataaaatt ggttatttaa
     2041 tatataatta caagtataaa taataaaatt tatttgtaaa aagagtagca cttttaattc
     2101 taaaggctac tttttttata caaaacccta ttttttataa caattcatta acataaaaat
     2161 caaacttacc ttaaaatata aatttacaaa tttttcaatc aataagaaaa tttctttatt
     2221 ccttacataa tgactgcaat gtaacaaaat aattacaaat taattatgaa atcattatag
     2281 ttagaaacct ctttaaaatt agatattaag tatcctttag aattagaacg ggaacaaagt
     2341 taaaaaatta agtaatatca aatggacaag ggggaagaaa ataaaatgaa aataccaaag
     2401 aagattgctg caatgcttac agttacaatg atagctggaa gttcaacagc aggcatagct
     2461 agtgcacaaa ctgtggcaac aaatttaaca gggcaagaaa gatatgaaac tgctgttaaa
     2521 ataagtcaag atggatggaa aaatgctgat gaggtagtaa tcgtaaacga ctcatctata
     2581 gcagatgctc tatctgcaac accatttgca aaagcaaaaa atgctccaat acttttaaca
     2641 agtaaagata aattaaatga taagacgaaa gcagaaatac aaagattaaa agctaaaaaa
     2701 gtatacttaa taggtggaac ttctgtatta agtacaaata tagaaaaaga aataaaagat
     2761 ttaaaaatat cttttgagag aatctctgga gctgagagat atcaaacatc cttagaatta
     2821 gcaaagaaat tagatgctat aagtgatgtt aagaaaatag ctgtagttaa tggtgaaaaa
     2881 ggacttgcag atgctgtaag tgtaggagca ccagctgcac aaaacaatat gccagtaata
     2941 cttgctgact ctaaaaatgg aacagcagtt gcagacaaat ttataaagga tgctggaata
     3001 actcaatctt atgtagtagg tggagagagt tcaatttctg aagctgttaa aaataaacta
     3061 ccaaatagta caagactagg tggaacagat agaaatgata caaatgcaaa agtaataaaa
     3121 gaattttata aaaagacaga tttaaaaaat gcttatgtaa ctaaagatgg tatgaataaa
     3181 caagaccaac ttatagatgc actagcagta ggtgtattag gtgctaaaaa tcaatcacca
     3241 gtagttttag ttggaaagaa cttatcagct tcacaaaaat ctctagttaa ctctaagagt
     3301 tttgataaga taactaaagt tggtgggaat ggtaatgaga cagcatttaa tgaaatgaag
     3361 tcattacaag aagtaaaaac agttgaagct aaaacaattt ctgaattaaa atcagctata
     3421 gataaagcta ctgctaatga tgttataaac tttaagccaa ctagtgaggt taaagaagca
     3481 tttacaatac aaactgataa agcagtaaca gtaaacttaa atggtacata tacaaagact
     3541 gtaactatca acatgcctaa tggagatgta aataactatg caaaagtgga tgatgtagtt
     3601 atagatgatg taaaagatgg aacttttgtt aattatggaa aaataactaa cttaaaggtt
     3661 aatgataaaa atggagccaa gatagaaaat aattctaaag gtgagattgg tagtttaaca
     3721 gtagcatctg gagcaagtca agtaaaagtg actaatggtg gtaagataac tacagttaca
     3781 aataattcta aagggactac tatagataat aaaggtacaa taagtagtgt taagggagat
     3841 aattctccaa caataagtgg aaatagtcca agttctaact cttcaggagg aagttcatca
     3901 agtggaggtt cttcacatgg aggaggctca tcttcaggag gaagttcttc taatcaaaca
     3961 tcagtaaata atgaagcagc aaaaataaca agcgtgccta caccagcaaa agatgcaact
     4021 agattaacta tgccatcagt atcaagtgga tatactatag caataaaaac atcaagtaat
     4081 gagagtgtta taaaaaaaga tggaacaata atacctccaa atacagcaac aacagtaaaa
     4141 ttagtattta cggtaacaca tacatcaagt ggtaaaacag cagatacaaa agaactatct
     4201 gtaacagtac cagctaaatc aacagatgaa gaattacaag cagcattaga caatgaagtg
     4261 gcaaaaataa caagcgttcc tgcaccagca aaagatgcaa ctaaattaac tatgccatca
     4321 gtatcaagtg gatatactat agcaataaaa acatcaagca ataagggtgt tataaaggaa
     4381 gatggaacaa taatacctcc aaatacagag gaaacagtaa cattggtatt tacagtaaca
     4441 caagaatcaa gtggtaaaac agcagataca ggagaaatag atgtagtagt accagccaaa
     4501 tcaacagatg gggaaataca agcagaagta caagctgagg cagataaaat aacaagtgta
     4561 actcagccaa cacaagatgc aacaacacta actatgccaa cagtagcaag tggatacaca
     4621 ataaagataa aatcatcaac aaatgaaagt gttatagcga aagatggaac aatagtgcca
     4681 ccagatacag aaacaaaagt aacattagta tttacagtga cacacacatc aagtggtaaa
     4741 a
//
LOCUS       DAEQAF010000162         4720 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.166, whole genome shotgun sequence.
ACCESSION   DAEQAF010000162 DAEQAF010000000
VERSION     DAEQAF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.166"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     misc_binding    293..531
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            595..2514
                     /gene="thrS"
                     /locus_tag="KRN00_003505"
     CDS             595..2514
                     /gene="thrS"
                     /locus_tag="KRN00_003505"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBH1829323.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     gene            3282..4373
                     /locus_tag="KRN00_003506"
     CDS             3282..4373
                     /locus_tag="KRN00_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBH1829324.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPRLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
BASE COUNT         1868 a          472 c          843 g         1537 t
ORIGIN      
        1 attgtattta agtatacaaa acctaaaaag agtacaaaaa ttagaagtta gttttaataa
       61 aaattagttt tagtatttat ctagtcatat ctatcatgca tgtggatacg ttttaaaaat
      121 tttaaattta tgaaaatatt ataatatcac tataaatcaa gagattaatt taatataaaa
      181 atataagaat attggtttac agctgattga gatgaaaaat aatgggtaat taatatatta
      241 cattaatgtt gattgatgta taactatctg ttataatgaa aatatattaa aaatcatagt
      301 gttgaagagg aagagtagag tagaaaccat tctcagagaa tttgggtcta tggctgagag
      361 cccatgtaat aggtctattt gaaaactacc ttggagctga gcttattagc agtatttgta
      421 tttgtactat acgtgaaagt gctcgggtga cgaccttata gtcatcaaga gggttgtata
      481 tacttgtata cgccaacttg ggtggaaccg cgaattaata tcgtcccaaa catatttggg
      541 gcgatttttt attacaaaaa atctaaaaat tatttcaata aggaggaaaa aacaatgatt
      601 aaagttgctt taaaagatgg ctcaataaaa gaatttgaaa atgctatttc tgttatggat
      661 gtagctaaat ccattagtga aggattagct agaaatgtgg tagcagcgtc tgtgaacgga
      721 gaggttgtag gtctggacca cattatagat actgattgtg acttgaattt atttaagttt
      781 gaagataaag aaggtaagga agtttttaga catacatcag cgcatatatt agctcaagct
      841 ataaaaagac tttacccaga agcaaagctt gctataggac caagtataga aaatggattc
      901 tactatgata tagatttaga ccatagatta gttccagagg acctagagaa aatagaagct
      961 gaaatgaaaa aaatagctaa agaagattta aaaatagaaa gatttgaact tcctagaaat
     1021 gaagctttag agcttatgaa agaacaagga gaagactata aggtagaact tatatctgat
     1081 ttacctgaaa gtgaaataat atctttctac aagcaaggtg attttactga tttatgtaga
     1141 ggaccacatt taccatctac taaaaaggta aaagctgtta aattacaaag tgtagcaggt
     1201 gcatattggc gtggtgacga aaataataag atgcttcaaa gaatatatgg aacttctttt
     1261 gagaaaaaca aagacttaga agagtactta catttactag aagaagctaa aaagagagac
     1321 cacagaaaat taggtaaaga attaggatta tttatgatac ctgaagaagg tccaggattc
     1381 cctatgtttt taccaaaagg tatggaactt aaaaatgaat tattaaaatt ctggagagaa
     1441 atacacagaa aagctggata tattgagata gaatctccaa tcatattaaa tagaaaatta
     1501 tgggagactt caggacactg gtatcattac aaagaaaata tgtatacagt taaaatagat
     1561 gatgaggatt atgctataaa acctatgaac tgtcctggtg gattaattta ctataactct
     1621 caactacatt catatagaga tttcccaatg agagttgcag agcttggtag agttcataga
     1681 catgagttat ctggtgcatt acaaggatta atgagagtta gagcatttac tcaagacgat
     1741 tcacatatat tcatgttacc agagcaaatt aaggacgaaa taaaaggagt agctaactta
     1801 atagatggta tatacaaaac ttttggattt gaatataatt tagaattatc tacaagacca
     1861 gagaactcta tgggaagcga cgaagagtgg gaagcagcag aaaatggatt aagagaagct
     1921 ttagaagagt taggtctacc atatactatt aatgagggtg atggagcatt ctatggtcct
     1981 aagatagact tccatctaaa agattgttta ggaagaactt ggcaatgtgg tactatccaa
     2041 ttagatatgc aacttccaag acaatttgat aatacttata ttggtcaaga tggtgaaaag
     2101 catagaccag ttatgattca tagggttgct tttggtagta tagaaagatt tataggtata
     2161 ttaatagagc attatgctgg taaattccca gtttggttat ctccaactca agttaagata
     2221 cttcctatat ctgataaatt tatggattat gcaaatgaag ttaagaaaga gttatttgat
     2281 aagggtataa gagttgaatt agatgataga gctgaaaaaa ttggatttaa gataagagaa
     2341 gctcagcttg aaaaagtgcc atacatgcta atagtaggtg aaaaagaagt agctgataat
     2401 aatgtttctg ttagatcaag agataaaggt gaaataggta gtattaaatt agatgaattt
     2461 atagctagta tttcaaaaga aattgaatca agagaaagta ttattcaaga ctaatatata
     2521 ttatattagt agctaagata ttgttatata agataagttt aatcaatatg ttgatatgtt
     2581 gatgcatagt gattaaattt atgaaaagat gagtataatt agaggtacag ttaatcatat
     2641 ttttatgatt aatgtacctc tagttttttg tatggtagat ttattaataa atatatcata
     2701 gaagtgtttt gaacatggaa atatttatgt gcattcttta aataaacgtt tattttttga
     2761 gtgataatta agtgcttgtt ggtaaggtta tggttgtaaa aatcataact ttattttcat
     2821 atttgttcaa ttttcataaa aattattatc cctttaagaa aatttcttaa tcctcttgaa
     2881 atatttcctt tttagtctaa agttaaattt ctttcttcaa aatgaatatt taaatgaact
     2941 aaaatttaag tacattttct aatcttatga gtctattttt catagataat tgccctataa
     3001 tagaagaatc tatgttggtg ctatgtggtg acaataacag cattgtcagt gattaattaa
     3061 tgctttataa atgattaatt agtgttttat gttatttttg gacttatcct ctatacatag
     3121 attaatttat ttaactttag atagagagag aatgtcaagt acatacacag acattagagt
     3181 ttaagaaagt gtttatggag caagaacttt taaaagaggt agtgacttag tttaatttca
     3241 agaaatgata aatacaaaag aggaaaaaga gaggtgttga aatgatagaa aaagtagaag
     3301 aaaaatctaa gattattaaa acatcaaaag aatataagcg aactataatt gaagaaaaag
     3361 ataaagaatg gaccaaaaaa ttaaatgata tacttagtag aagtagtttt tctaatgatg
     3421 aattagataa aatcaaggca ttaattccaa aagagatttt gactaatgaa aatgttggag
     3481 aagttgtgac tgaagatgga tatgctaagc ctgagtatga tgaggtattt aaatcattgt
     3541 tcactttaaa taatgaatat gatttacttg taaattttat aaatgatatc ctaaaagatg
     3601 ctccatatgc taacaggaat atcaaaccgt tcactcaaat aaagagaata attagagttg
     3661 aaactgaccc aacaattaat tacattggag agaaaagacc tagacttgat attttggctg
     3721 aagatgaaga aaataatcat ataaatattg agatgcaaag agcttttgag aacgattatt
     3781 tggaaagagc tgaatattat cttagtcgtg tacatggtag aaagttagaa gaaggtaaag
     3841 agtataaaga aattggaaaa actattggaa tacatatact aaatcatgta aaatataatc
     3901 acatagaaga ttatgtaaat tgcctgagat taacaatgga cgggcatcca gatatttatt
     3961 ctagtaaaac tgcattatat tttatagagc ttccaaaaat tcataaatct gactatatag
     4021 taaatagaat tatgctatgg ggaaaactta ttagtaatcc ttctaactta gatgtaagag
     4081 ttatagctaa gaatgattct attattaaaa aagcacttga tagattaaaa gaattaggta
     4141 gcaatgaaga atatttatta aatctgaaaa gaggtgctta tatcatgaat aaaagtagaa
     4201 attttaaaga agagattgaa agagagacag caattagagt tgcaaaagaa aaagattata
     4261 aaataattat aatgttgaaa aaaaatggtt ttaaattaga tgacatatta aataaattta
     4321 atgattttga cttaagtgaa gatgagataa aagaagtata tgaaaataat tgatgataaa
     4381 taaaaagtga acttatataa gtttgctgaa tcggagtctg gaaatattta tgtgtatttt
     4441 ttaatgaatg aaaatttatt ttaaaaacaa taatttagaa gtacagttaa ttatattttt
     4501 atgatactgt acttctagtt ttttctattg tagatttatt atttactaat aaatctacaa
     4561 tagaaatgct tttgttgtaa gaatcatttt atctaatgat tgttttttat aatagttaaa
     4621 tttccatttg tagtgtttaa atataaatct ataacagcat ttctataaat gttataaatc
     4681 actataatga ttcaactcaa agttactgct taaagaagca
//
LOCUS       DAEQAF010000163         4692 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.167, whole genome shotgun sequence.
ACCESSION   DAEQAF010000163 DAEQAF010000000
VERSION     DAEQAF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4692
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.167"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            137..1045
                     /locus_tag="KRN00_003507"
     CDS             137..1045
                     /locus_tag="KRN00_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBH1829325.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            1050..3419
                     /locus_tag="KRN00_003508"
     CDS             1050..3419
                     /locus_tag="KRN00_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBH1829326.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFKSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            3744..4547
                     /gene="proC"
                     /locus_tag="KRN00_003509"
     CDS             3744..4547
                     /gene="proC"
                     /locus_tag="KRN00_003509"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBH1829327.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEEFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
BASE COUNT         1891 a          511 c          910 g         1380 t
ORIGIN      
        1 ctaaaaatat atagacaaaa taataacaaa tatagtatta tgtaattgta gaaatgcttt
       61 tcataggtat attctatgaa gatgaattgc ataaaaatga aaaaatggaa tggatattat
      121 ttaggggtga aaaatcatga atccattagt tataaactta caaaaatgta gcatacatga
      181 tggaccaggg ataagaagta cagtattttt taaagggtgt ccacttgaat gtgtttggtg
      241 tcataatcca gagagtcaaa catatacaaa acaagttttg tataatgaag aaagatgttc
      301 aaaatgtgaa gcatgtataa atatatgccc tcataaggca atttacaaag gtgaaacaaa
      361 aatatgctta gaccaagata agtgtgagtt ttgtgaaact tgcttagact attgtgtaaa
      421 caatgcaaga gagattgttg gtcaagagta ttctgtaaga gatttggtta aagagataga
      481 gaaggataga attttctatg aagaatcagg tggtggagta actctatcag gtggagaagt
      541 aatggctcaa gatatggact tcatttgtgg agtaataaac atgtgcaaat caaagggaat
      601 ccatgtagca attgatacat gtggctatgc aaagtcagaa aattatgaaa gagttgctaa
      661 atgtgcagat ttgtttttat atgatattaa gcttattgat gaagataagc acataaaatt
      721 tacaggaaaa tcaaatgact taatactgaa aaatgttaag attttaagtg aattaggggc
      781 taacataaat ataagaatac cattaattgt aggagtaaat gtagatgatg aaaatttaga
      841 ggttaaaaaa atgatagagt ttttaaagcc tttgaatata caagcagtaa gtcttcttcc
      901 atatcataat attggtaaac acaagtatga taaaatttat aaaaagtatg aaggagaaga
      961 actacaaaga ccatcagaag aaaaattaga ggaaataaaa agactgtttg aagcaagtaa
     1021 tttcaatact aagattggag ggtaataaaa tggcaagagg aacttttgag agaactaaaa
     1081 aattaagaga agaaagtatt aatgcagagc cacacatatc tattgaaaga gcagtactta
     1141 tgacagaagc ttataaaaaa tatgagggaa gtgtagagat tcctgtactt cgtgctttat
     1201 catttaagca ttatattgag aatagaactc ttagtataaa tgatggagaa ttaatagtag
     1261 gtgaaaaagg tgattctcct aatggagcac caacatatcc agaaatttgt tgtcatacaa
     1321 tggaagattt agaagtaatg cacaatagag atataataaa ttttagcgta tcagaagaag
     1381 ctagaaaaat acataaagaa gaaataattc ctttttggaa aaagagacaa acaagagata
     1441 agataataaa tgcaatgaca cctgagtggt tagcagcata tgaagcaggt atgtttacag
     1501 agtttatgga acaaagagcc ccaggacata cagtttgtgg agatacaata tataaaaaag
     1561 gatttttaga tttaaagaaa gacatagaag caagattaaa agagctagat tttcttaatg
     1621 atttagatgc atataataaa aaagcagatt tagaagctat ggcaatagct tgtgatgcaa
     1681 tggttatatt aggtaaaaga tatgctgaga aagcaagaca aatggcagaa gaagaaacag
     1741 atgaagctaa gaaaaaagat ttattactaa ttgctgaaac ttgtgatgtt gtaccagctc
     1801 acaaaccaga aacttatcat caagctatac aaatgtattg gtttgttcat ataggggtta
     1861 ctactgaact taatatatgg gatgctttta ctccaggaag acttgaccaa catctaaatc
     1921 ctttctatga aagagatgta gaaaatggaa tactagatag agatagagca caagaattac
     1981 ttgaatgttt atgggttaaa tttaacaatc agccagcacc accaaaagtt ggtataacat
     2041 taaaagaaag tagcacatat acagattttg caaatataaa cactggtgga ataaatccag
     2101 atggtcaaga tggtgttaat gaagttagtt atataatact tgatgttatg gatgaaatga
     2161 aattgataca acctagttca aatgttcaaa taagtaaaaa gactcctcaa aaattcttaa
     2221 agagagcttg tgaaatatca agaaaaggat ggggtcaacc agcattttat aatactgaag
     2281 caatagttca agagcttatg gaagctggaa aaactataga agatgcaaga cttggtggaa
     2341 ctagtggttg tgttgaaact ggatgttttg gtaaagaagc atatgttcta actggatata
     2401 tgaacattcc aaaaatactt gaattaacat taaataatgg atatgaccca attagtaaaa
     2461 aacaaatagg tattgaaact ggagacccta gaaatttcaa atcttatgag gaactatttg
     2521 aagcatttaa aaagcaatta cattatatga ttgacataaa aatagaagga aatgctgtga
     2581 tagaaaatat atgtgcaaaa cacatgcctt gtccacttat gtctacaata gttgatgatt
     2641 gtatagaaaa aggcaaggat taccaaagag gtggagcaag atacaacact agatatatac
     2701 aaggtgttgg tataggaact ataacagata gtttaacagc aataaaatat aatgtatttg
     2761 ataagaaaaa attcgatatg gatacattgc ttaaagcact tgatgctaat tttgaaggat
     2821 atgaagctat acttaattta gtttcaaata agactcctaa atatggaaat gatgatgatt
     2881 atgctgatga aataatgcaa gagatattca atgcatatta caatgaggta actggtagac
     2941 caactgtttg tggtggagaa tacagagtag atatgttacc aacaacttgt catatatact
     3001 ttggagaaat tatgggagca agtccaaatg gtagactttg tgcaaaacca gtttcagagg
     3061 gaatttcacc tgaaaaaggt ggagatacta atggacctac agcagttata aaatcttgtg
     3121 ctaagatgga ccacataaaa actggtggaa cattattaaa tcaaagattt gcaccatcag
     3181 tagttcaagg agaaaaaggg ttagataata tggctaatct agtaagagca tactttaata
     3241 tggatggtca tcatatacaa tttaatgtat ttgataaaaa tgtactgtta gaggctcaaa
     3301 agaatcctca ggattataaa gacttaatag ttagagttgc aggatatagt gaccatttca
     3361 ataatttaag tagaacacta caagatgaga taataggaag aactgagcaa acattctagg
     3421 tttgcttgta aataaaactt cttactatat aaaatcgtaa ctgatataat aaagtataaa
     3481 tggtttgatt ccatttttaa aattttagat taattatgag ctaactttct aaataggaag
     3541 ttagctcgtt aagtttaatg aaaaaatcgt taaatttata tttagtaaat catacacata
     3601 ttagtaagta atacatacaa aagaataatt tattatagtt ataataaggt tatattttat
     3661 aaaaataaga taattttaag cagttaaaat aaagtcaatt tagctacttt aaaataaaac
     3721 taatagaaaa aaggagattt gatatgaaaa ctttaggatt tattggttca gggaatatgg
     3781 gaagtgcaat gataggtggc atagtacagt caggattagt aaaggcagaa gatataactg
     3841 tatcagattt aagccaagtt gccttagata aagtaaaaga agaatttgga gtaaatacta
     3901 caactgattc aaaggtagct gttacaaatt ctgatgtggt aatagtagca cttaaaccta
     3961 atatatgcga aaaggcttta actccactta aagaattaat agatgcaaat aaaataatag
     4021 tatctatagc agcaggtaaa actatagaaa gtctggaaag ttttataggt tcagataaaa
     4081 aaatagtaag agtaatgcct aatactccag cccttgttgg cgaaggaatg tcagctcttt
     4141 gtaaaaatag taatgtaaca gatgaagagt taaatatgat taaggctctg tttgaatctt
     4201 ttggtgaggc agaaatagta tcagaatatt taatggatac agttacaggt attagtggtt
     4261 cttctcctgc atatgtattt atgtttatag aagctatggc agatgcagca gtattagctg
     4321 gaatgccaag acaacaagct tataaatttg catctcaagc agtaatgggg tcagctaaga
     4381 tggttcttga aactggaaaa catccaggtg aattaaaaga tatggtttgt tctccagcag
     4441 gaactactat agaagctgtt aaggtattag aagaagaagg ctttagagca gcagttataa
     4501 aatctattgt tgcttgtata gataagtcta aagatatgag caaataacag atgtaattaa
     4561 gtttactata tggtttcttg aattgttttt tagtgcttat ttatatctat acataaatgt
     4621 atttggtata agtaaaataa gagtaattta ctataaaaag gaatttaatg attgagtgag
     4681 aatttattac tt
//
LOCUS       DAEQAF010000164         4292 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.168, whole genome shotgun sequence.
ACCESSION   DAEQAF010000164 DAEQAF010000000
VERSION     DAEQAF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4292
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.168"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            113..1711
                     /locus_tag="KRN00_003510"
     CDS             113..1711
                     /locus_tag="KRN00_003510"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBH1829328.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(1946..3910)
                     /gene="bclA1"
                     /locus_tag="KRN00_003511"
     CDS             complement(1946..3910)
                     /gene="bclA1"
                     /locus_tag="KRN00_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBH1829329.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPVGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECPPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGSIGPTGPTGNTGATGSIGPTGVTGPTGSTGATGSIGPTGVTGPTGNTGVTGSIGP
                     TGATGPTGNTGVTGSIGPTGVTGPTGNTGEIGPTGATGPTGVTGSIGPTGPTGEIGPT
                     GATGATGVTGSIGPTGPTGPTGATGVTGEIGPTGEIGPTGATGPTGVTGSIGPTGATG
                     PTGATGEIGPTGATGPTGVTGSIGPTGATGPTGATGEIGPTGATGPTGNTGVTGEIGP
                     TGATGPTGNTGVTGEIGLTGATGPTGNTGATGSIGPTGVTGPTGATGVTGPTGPTGNS
                     SQPVANFLVNAPSPQTLNNGDAITGWQTIIGNSSSITVDANGTFTVQENGVYYISVSV
                     ALQPGSSSINQYSFAILFPILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGTTFTINNF
                     SSTTVGIRNGQSAGTAATLTIFRIADTVMT"
BASE COUNT         1292 a          752 c          648 g         1600 t
ORIGIN      
        1 atataatatt ttttcactaa atttttttct ttttacaaca aatactcact accttttgat
       61 ataatatttt tatcaattat tattatattc aagttttgaa aggagtatta aaatgagttt
      121 attagttttc ggacataaaa atccagatac agattcaata tgttctgcaa tttcattagc
      181 acatttaaag aacaaactag gaataaaagc aacagcttat gctttaggag atatcagaaa
      241 agaagctaaa tatgccttgg attactttaa ggtagatgca cctgaaattt tagataatgt
      301 tagaatacaa gttagagatt taaattatga taaagtagta cctttaacac caacttcatc
      361 tatattagag gcttataacc ttatggatga aaaaaatgtt aaaacactac ctgtaactta
      421 tgatgatgga acttttgctg gtatcattac tatgaaagaa atagctaaaa atctacttca
      481 tcaacacttt acaactatac acacatcact atcaaacatt tgtaaaaacc ttaatggtac
      541 tattcttgtg gactgtggtg aagatataaa aggtagagta gtcactttat catttggaat
      601 ggagactcta atagagactt taaaagaagg agacatagct attgttggag atagatatga
      661 tagtattgaa tatgctattg atacaaaagt taaactttta atacttacta atcatacaga
      721 gatttcaaaa gatttgctag ctcttgctaa gataaatgga gtgtctgttg tttctgttga
      781 aagtgacaat tataaaactt ctaatgtaat aaatcaatgt agtttcttag actctataga
      841 agctacagaa aatttaatta cattcaaaga agatgattat atggatgaaa taaaagagat
      901 tatgctagaa acaaacttca gatcttatcc aatattagat gatgataata agtttttagg
      961 tttagtttca aaaggtcatc tattaaaccc atctaaaaag aatgttgttt tagttgacca
     1021 taacgaatat gctcaaagtg ctgatggaat tgaacaagca aacatagttg aaataattga
     1081 ccatcataaa cttggtggta tttctactga tgttcctatg tcatttagag ttatgcctgt
     1141 tggatgcaat agtactataa tttatcaaat gtacaaagaa aataatgttg agatacctta
     1201 tgaaatagct gggcttcttt tatctgctat attatcagat acattattat ttaagtctcc
     1261 aacaacaact gatatagata agaaagcttg tgaagaatta agtaaaatag caaaagtaga
     1321 catggaaaaa tacgctatgg acatgtttaa atgcggtact tctttagatg aatatactat
     1381 agaagaaata gtaaatatgg attttaaaga atttaatatg agtgggcata gagttggtat
     1441 tggacaagta tttaccttag acatagactc tatatttgct aaaaaagatg agtttttatc
     1501 ttatataaat tcgactgatt atgataaatt aattctttca gttacagata taatcaaaga
     1561 aggttcttat ttaatctata aagcagaaga tagcttaatt gctaacgcat ttggtgttga
     1621 aggtgttcaa ggcacatttg caccaggtgt tgtatcaaga aaaaaacaat tagtccctaa
     1681 tttaactact gcaatcaaaa attttaaata atataaaatt tttaaataac gaaaactgtc
     1741 tcaaatctat atttgagaca gttttttatt atatatatat tgataataaa gttaaataaa
     1801 aatccataaa tttaaaattt ttatgaatat attttattat tattgttatt ttattcattc
     1861 taaaataggt aaaactcaat atataaaaat acttttgtca tttaaataaa gcctaaatag
     1921 tttttaagat tattttagac acgttttaag tcataacagt atcagctatt ctaaatatcg
     1981 tcaaagtagc cgcagttcct gctgattgcc catttcgtat ccctactgtt gtagatgaaa
     2041 aattatttat tgtaaaagta gtcccaccaa ataaaaaacc agcaaaatat ccagaaagta
     2101 ctcctccgcc tcctggctca gtagtaagcc ctgccaaatc ttttcctcct aaaattggga
     2161 ataggatagc gaaagaatat tgatttatac ttgatgaacc tggttgtaat gctactgaaa
     2221 ctgatatata atacacacca ttttcttgta ctgtaaacgt accatttgca tctactgtta
     2281 tacttgaact atttcctatt attgtttgcc aacctgttat agcatctcca ttatttagtg
     2341 tttgtggaga tggtgcattt acgaggaagt tagcaactgg ctgagaggaa ttgcctgttg
     2401 gacctgttgg gcctgttact cctgtcgctc ctgttggacc tgttactccc gttggcccta
     2461 tacttcctgt cgctcctgta tttcctgttg gtcctgttgc tcccgttagt cctatttctc
     2521 ctgtcactcc tgtatttcct gtcggacccg ttgctcccgt tggtcctatt tctcctgtta
     2581 ctcctgtatt tcctgttggg cctgttgctc ccgttggtcc tatttctcct gtcgctcctg
     2641 ttgggcctgt tgctcccgtt ggtcctatac ttcctgtcac tcctgttggg cctgttgctc
     2701 ctgttggtcc tatttctcct gtcgctcctg ttgggcctgt tgctcccgtt ggtcctatac
     2761 ttcctgtcac tcctgttggg cctgttgctc ccgttggtcc tatttctcct gttggcccta
     2821 tttctcctgt cactcctgtc gctcctgttg gacctgttgg tcctgttggt cctatacttc
     2881 ctgtcactcc tgtcgctcct gttgctcccg ttggtcctat ttctcctgtt ggtcctgttg
     2941 gtcctatact tcctgtcact cctgttggac ctgttgctcc cgttggtcct atttctcctg
     3001 tatttcctgt tgggcctgtt actcctgttg gtcctatact tcctgtcact cccgtatttc
     3061 ctgtcgggcc tgttgctccc gttggtccta tacttcctgt cactcccgta tttcctgtcg
     3121 gacctgttac tcctgttggt cctatacttc ctgtcgctcc tgtacttccg gttgggcctg
     3181 ttactcccgt tggccctata cttcctgttg ctcctgtatt tcctgttggg cctgttggtc
     3241 ctatgcttcc tgtcgctcct gtacttccgg ttggtcctgt tactcccgtt ggtcctgtac
     3301 ttcctgtcgc tcctcttggt cccattggac ctgtaattct aattggagga cactcacatt
     3361 taggataaca attatctata attctatctt caaatgttac aagtatatac ggtttgttac
     3421 aacctctact agatgtaaat tcaagaatct gataagggta atttaaagat aaagctaacc
     3481 cataattagg atatttattc attgcccatg cttttatagt tcctgtaata tttaaacaaa
     3541 tatagttgga tgtatcactt atcccaactg gtaaatatcc cctaatattt tccatagaca
     3601 ctctatcatt ccatgttata gttcgtaaat tataatattc acttattctt ttaatttcaa
     3661 tatctacttt ttctttaaaa atatgattct tatttgaatc aatatgaata aataactctg
     3721 cttttaatat acttttgtct tttaatatat ctggtattct cactttaaaa aaagtaatca
     3781 acttttcttt tacaaaacta tttgaacatt tacttcctat taagcaataa tctaaattac
     3841 taaagttttt atctggatat tttttagata taaaagtatc atcatttaaa taaagtataa
     3901 tatttctcat ttataatccc tccattttgg gtctatatca tactatgttt aaaatgcatg
     3961 cttagttaca atacaattaa aatttatagt attaaatttt tatataataa tgctgatttc
     4021 tacaaaaaaa gaacatgtca ttagaaattt ctaatagcat gttctttttc attattatat
     4081 attacacttt aaattattcc ttgactggct tagctggtgt aaactaaacc agtctttcta
     4141 aaatattaag cacttttttc ttattatgtt ttttaggatt tattgtctat attattgtaa
     4201 accaaagtta taaaattgta aatagaatat attaccataa caatattttt ttataagtaa
     4261 aaattataaa aaactttatt tttgttaaat ag
//
LOCUS       DAEQAF010000165         4207 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.169, whole genome shotgun sequence.
ACCESSION   DAEQAF010000165 DAEQAF010000000
VERSION     DAEQAF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4207)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4207)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4207
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.169"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            47..1741
                     /locus_tag="KRN00_003512"
     CDS             47..1741
                     /locus_tag="KRN00_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBH1829330.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSYFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYIRMMRSDYREYMIKNVRKQVLKYVVPMANELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIKNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      2073..2183
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            2287..2658
                     /locus_tag="KRN00_003513"
     CDS             2287..2658
                     /locus_tag="KRN00_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBH1829331.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            2753..3700
                     /gene="trxB"
                     /locus_tag="KRN00_003514"
     CDS             2753..3700
                     /gene="trxB"
                     /locus_tag="KRN00_003514"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBH1829332.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            3785..4102
                     /locus_tag="KRN00_003515"
     CDS             3785..4102
                     /locus_tag="KRN00_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBH1829333.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
BASE COUNT         1746 a          390 c          785 g         1286 t
ORIGIN      
        1 tatatttata aatacaataa agtaaggttg taaaggagtg ctttaaatga agttttcaga
       61 gtttaagtat gaaagaccca attataatag tatgaaaaaa gagtttttga gttgtgtaga
      121 agatataaat aattctcgta attataaaga gcaacaaaaa aatatacata agattaattt
      181 attaagaaat aaaatagaaa cgttgtcaaa tatagcttcg ataagatata gtacagacac
      241 atttaataaa ttctacaaag aagaaaaaaa ttattgggat gaatatatgc ctttgtatga
      301 agaattaaat tcatattttt ataatgccat tgtaaattca aaatttaaat atgatttgat
      361 aaaagagttt ggagagcaat ttttcacaat agtagagtat tctttaaaaa gtttttccaa
      421 agaaataata agtgaattgc aggaagaaaa taaattgtgt tcagagtata ctagactttt
      481 agcttcagct gagataatgt ttgatgggaa aataagaaat ttatctggta tggggaaatt
      541 catgtattct aagaatagaa aaacaagaga attagcaaac aaagcatatt ataatttctt
      601 tgaagaaaat gaaactaaat ttgatgatat atttgataaa ttggttaaac ttagagataa
      661 gatgtctaaa aaattaggtt ttgaagattt tgtagagctt gggtacatta gaatgatgag
      721 aagtgactac agagaatata tgataaaaaa tgttagaaaa caagtactaa aatatgttgt
      781 tccaatggca aatgagcttt atgaaaaaca agctaaaaga attggtctag aatatttaag
      841 ttacatagat gaaggcgtgg aatttttaac aggaaatgca agtttaaagg gagattcaag
      901 atacataatt aaaaatggta aaaggatgta ttctgaactg tcaaaagaaa caaatgaatt
      961 ttttgatttt atgttagaaa atgaacttat ggatttagaa acgaagaaag gaaaaggagc
     1021 tggagggtat tgtacttata taccagatta taagtcacca ttcatttttt ctaattttaa
     1081 tcaaactgct gatgatatag atgtattaac acatgaggca ggacatgcat ttcagttgta
     1141 tatgtctaga tggattgata tgccagaaat taattttcca acgcttgata gttgtgaaat
     1201 ccattcaatg agtatggaat ttataacatg gccgtggatg gatttatttt ttaaagaaga
     1261 tacagataag tacaaattca ctcacttatc atcttcaatt aaatttatac cttatggagt
     1321 aattgttgat gaatttcaac actatattta caaaaatcct aatgtagata agtcaaaacg
     1381 aaaagaaatc tggagatttt tagagaaaaa atacttacct catagaaaat atggtgataa
     1441 ttctttttta gagagaggtt gttggtggtt taaacaagga catatattta aaaatccgtt
     1501 ttattatata gattatgtat tagctcaaat ttgtgcgtta caattttgga aaaaaatgat
     1561 tcaagataga gatgcaggat ggaaagatta tataaatatc tgtaaagttg gaggaacaaa
     1621 atcattttta gatattgtga gtatgggaaa tttgtattct ccatttgatg atggctgtat
     1681 tgagtctatt ataggtgatg ttaaatcttg gtttgatgaa ataaatgaca gcaaattata
     1741 aaaaattatg agaattttat tgtataaaag taaaaaatta aaaaatatat aaaaagtgat
     1801 tatttgttgt gaaaatagtc ttgtttttaa ctaaattgat aaaataaact aaaaaagatt
     1861 tgtacttaaa aaaaaaagaa aatacaagaa atatgcaata tcaacatttg gaaaaaaaag
     1921 taaaaatgta tacaaaatac atataaaaaa actattgcaa attttataga atgtttatat
     1981 acttaagtca acagagatag aaaaaagcta tttatagaaa acaaaggata aattgcttaa
     2041 ttttaaattt tctgaaaaaa ataataatcc ggatgaagag tatgggagac tgctttataa
     2101 aaagcgaccg aagggacaag tttaatctta cttacccaaa agattagatg aaattctcag
     2161 gtaaaggtga ctgtacttgg acggggctct gaaaatgatt ttaacaggga agacaaattg
     2221 ggagatttgt ttttcctgtt ttttatttat caagtaataa ataaaagttt gaaagagagt
     2281 aaaaaaatga taataattac gaataatcca aaagtaaaag aagaagttca aggcagagaa
     2341 gttttgttta aagacacaac ttatattgga atcttagaag caagtagaga tttgatacat
     2401 gaaggttatg aacttttatc tcatccactc tatgggagtg taaagccaaa tgaaacacct
     2461 tacaggactg ttatactaaa gaaaggaaat cgtttggata taaactcttt aaccttaatt
     2521 gaagaagcaa tcatcactgc aagtaaattt cagaataata aaaagactcc aaaatggaca
     2581 gaaagtgttc aagatgattt tagagtaatt gattatgata tattttataa tacaatacaa
     2641 agaatgcagt atgaataaaa aaattgttaa aaagttatta aaacagccta aatattaaat
     2701 ctaatttaat attaaataaa atgagaaatt taattgggga ggataagtca aaatggaaaa
     2761 tgtgtatgac ttagtaataa ttggttcagg accagcaggg cttgcagcag gtctttatgg
     2821 agcaagagca aagttaaaaa ctctaatcct agaaaaagac aagactggtg gacaaattgt
     2881 aataacacat gaaattgcaa attatccagg gtcagttcca aatgcaacag gaccaagttt
     2941 aatagctaga atggttgaac agtgtaaaga gtttggagca gaaatgctaa gagacaacat
     3001 tgttgatact gagctagatg gagatataaa agttttaaaa ggggaaaagg cagaatatag
     3061 agcaaaagca gtaataatag gaacaggagc aacaccaaga aagattggtt gtcctggaga
     3121 aaaagaactt actggtaaag gggtttcata ttgtgcaact tgtgatgcag atttctttga
     3181 agattttgaa gtatttgttg taggtggagg agacagtgca ttagaagaag caatgtattt
     3241 aactaaattt gctagaaaag taacaattgt acatagaaga caaggattta gatgtgctaa
     3301 gagtgttgaa gaaaaagcaa aagctaatcc aaagatagag tttttattag atacagtaat
     3361 tgaagaaatc aaaggtgatg gaatattaga atcagttgta tttaaaaata aagttactgg
     3421 agaaactcat gaatactttg cagatgaaga agatggaaca atgggagtat ttgtgttcgt
     3481 tggattagat gctcaaactg atttattcaa aggtaaagtt gatatggatg aaaaaggtta
     3541 cataataact gatgaagata tgagaactaa cataccaggc gtatttgcag caggagattg
     3601 tagatctaag actctaagac aggttgtaac tgcaactaat gatggagcaa ttgcatctat
     3661 agtagctgag aaatacattg atgaaaaatt tgggaactag aatctgtaaa ttaagaaata
     3721 gtgtctgtaa atttaatgaa taatatttaa aattaaaata aaaatttcaa gggggaataa
     3781 gaaaatgtta gatttagata aggctacatt tgaagaagaa gttttaaatg cagaaggttt
     3841 tgtatttgtt gatttttgga gtgaaggttg tgagccttgt aaagctttaa tgccagatgt
     3901 tcataaatta gctgagactt atggggataa aataaaattc tgtaagatgg atacaacaaa
     3961 agctagaaga ttagctataa aacaaaaagt attaggtctt ccaactatgg ctatatacaa
     4021 agatggagaa aaagtagacg aagttactaa ggatgatgct acagttccta atatagaaaa
     4081 catgattaaa aaatatcttt aatatgttga taaattatta acattaaaag aaaaaatcta
     4141 tttttatctg aagataagaa gaaaaaggtt tttatgtcca actttgttaa aaaaataatt
     4201 ttaaata
//
LOCUS       DAEQAF010000166         4127 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.170, whole genome shotgun sequence.
ACCESSION   DAEQAF010000166 DAEQAF010000000
VERSION     DAEQAF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4127
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.170"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            12..764
                     /locus_tag="KRN00_003516"
     CDS             12..764
                     /locus_tag="KRN00_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBH1829334.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            751..1632
                     /locus_tag="KRN00_003517"
     CDS             751..1632
                     /locus_tag="KRN00_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBH1829335.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNIADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKKINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(1858..3213)
                     /locus_tag="KRN00_003518"
     CDS             complement(1858..3213)
                     /locus_tag="KRN00_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBH1829336.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
BASE COUNT         1613 a          599 c          519 g         1396 t
ORIGIN      
        1 ggagtttcta tatggataat ataattaatg aattacaaaa tataggattt actaaatacg
       61 aatctcaaat atacatatca ttattaaagg aaagcccttt aacaggatat gaaataagta
      121 aattatcagg tgtaccacaa tcaaaagtct atgaaaatat aacaaagcta ttaaacaata
      181 atataattat caatgttgga actgacccta ttaagtacat accaataaac cctaatgaat
      241 tattaaaaaa taagaaaaaa gaatttgaca attctatgga taatctaaag aatagcttac
      301 agatattaaa taaaagtaaa agtgtagaat acgtattaaa cataaaagga gataaaaata
      361 tattaaaaaa agcaatagaa atgataaaaa atgcgaaaca agaaattata atttcttgcc
      421 cttatgaaga aattcttgaa ttaaaaaaag aactcctaat tgcttacaaa aaaaatatta
      481 atattgaaat actactttta gaaaacaaaa gtctgaaagg tcttgataat attcatattc
      541 atggaggtaa taaaactaca cttgaaaata aaatgcttta caaaggaatt attttgattg
      601 tagataatga tgaaatattg acaggaaact tatcagaagg cagtgaggcc atttcaattt
      661 ggacaaaaaa ctctaacatt ttatatattg gagttcaata cataaaacat gaaatttata
      721 tttcagaaca aataaaagga ggttataaaa atgaacaaaa ttaaaattaa acaagttgat
      781 gcttttacaa ctataccttt tggtggaaat cctgctggtg tcgttactga tgcctctaac
      841 atttctgatg aaattaagca gaatgtggct aaagaaatga atttatcaga aactgcattt
      901 gtttcagagt caaatattgc agattttaaa gtacaatttt tcacaccagg tttagaagtt
      961 gatttatgtg gtcatgcaac aataggtact ttccatgcac ttttggaaga agggaagctt
     1021 aatactaata agagtatatt ttatcaagaa acaaaagctg gtgtattatc tgtagagctt
     1081 aagaaaataa ataatgaaaa tatatttatg atggaacaga atacacctga atttgaaaat
     1141 ttagataatt gcagaaaaga acttgcacaa atgataggtg tgcatgaaga tagacttctt
     1201 gaatatccta ttataaaggt aaatactgga ctttggtggc ttgtatttgg tctaaaatct
     1261 ttagatgatt taaaaaatat ctctccagat ttaaataaaa tcaaaaaatt tagtggtgat
     1321 aataatataa ttggtataac tccattttgt atagaaacta tagataaaaa gtgtgactac
     1381 catttaagat ctatagcacc atatgttgga gttacagaag accctgtatg tggaactggg
     1441 aacgcttgcg tatcatctta tatagtacat cacaatattt tagataaaac tagttttatt
     1501 ggtgagcaag gtaactttat aaacagacct ggaaaggtat atgtaaatat aactagagaa
     1561 aacaatgaca taacttctgt aaaaattgga ggaagtgctt atactgtttt aagtggtgaa
     1621 attatgtatt aatcccatac ctaataaaaa caaataaaaa tactagctaa ctaaagctag
     1681 tatttttatt tgttattttt atttaataat catactctaa caaatattat aattatatat
     1741 atcataatat tgtatttaga agtaaaattt tatttttatt attaattagt tataaatcaa
     1801 tctaatacaa cataattaca gtagattaac ctataaaaca taataattgc ttactgatta
     1861 tttatcgtcc tcaacaagtc tacttaatgt cttatcagat aagaataata atatcgctgc
     1921 aacaaatagt attactggaa ttatagtata tactttaatc atatcaaatt taagagtaaa
     1981 tgcatatata tatccgtatc ctttaccagc tataaaagta gcaaatgtcc atactcccat
     2041 aagaacacct agaagcttct taggtgcata cttacttaca aaagagttac caagtggtga
     2101 gaataacatt tcaccaagac ttaaaagaat accaaacatg attatccata gtatactagc
     2161 tttagcagtt tcaggagctc caacccctct tgaaaattct gcaccaacaa gcattaagaa
     2221 tgcaagacct aagaatatta atccaagacc tgtcttttta aataaactca tatctccttg
     2281 tggtctacta gcaagtttaa accataatgc tccaagaact ggtcctaata ctatacatac
     2341 aagtgaattt aatgagtcaa accaagcaag aggaacatca aatcctccaa cattcatgtt
     2401 tacaaatgct gcaccataat cataaactgc aagataagtt agataccaga atacccagaa
     2461 aattacagag aagaatgata taagtataat agcccaaatt ctcttcttat ccatgcttgt
     2521 aagaggagac ttatcttttt cttcaatttt ttcagcaact acaccttctt taaaaggtct
     2581 ctttcctgca ttcccaagga atctccatcc atatatgaac catattgcac ctattacaca
     2641 aagtacagct gctataaaga aacattgaga aaatccaagt acaccatttt ttgcaaatgt
     2701 tttaaggtaa agaataccaa ctgctatagt accaataaaa gaacctatat taacaaaaga
     2761 atactgtact gaaaatgctg tatcaagttc ttcttgacta tcaaaaagct gtccatttac
     2821 cgcagatacg ttacctttaa agaatgcagt accaattgaa actaagatta tcattgcatt
     2881 taccatagaa actgtagttg caatagaacc aagatagtat cctactccca tgataagcat
     2941 acctataggt atagtatatc tagctcctat ccatctatct gatatatatc ccccaattat
     3001 aggtgcaagg tatgtgaatg caacaaggtt ggcttgcatt atagcagctt gtcctttatc
     3061 tattccaaga ccaccatgaa ctatagctgt tgtaaggaat atatatatta agtactttga
     3121 agcataatat gctgctcttt caaatgagaa agttgttgag cagatataaa atcccatagg
     3181 aaatttaccc ttctttttta ctgttgagct cataatttta aatcctttct taattgtatt
     3241 tttatttttt acgttttgtc caaattcttt cttttatgaa agatataata ttattatttt
     3301 gtaaaacaat ttgtaattat tattaagata attgcgcatt tatttgtaga gtacatattc
     3361 tcatggaata aaattaatac acttcttaat cataaattta aattatataa attcactatt
     3421 ttcagatata gttataaatt aatatattct catctaatac catgaaaaaa ccttcgccat
     3481 atgcaattct tattttttac gtgatagtat tttacaaact aaaatccccc ttttgtagca
     3541 acttatgtaa ttacatttta gtgctttttt aaaggagtct cgaataaagc aacatatatt
     3601 ttgttcaaat aatgttttta tttatttttt aaatttatat attacttcac tcaaccaatt
     3661 ctcaacttaa ataactaaac tactatctat tcacagatta ggcttatttc ttacacatta
     3721 gtttataata aacactgtga atctaaacat aaaaactgtt attttaaagt aattacccat
     3781 atattcgctt tgatactatt tattgaggtt atactcttta tgtataatat attatttata
     3841 aaatacctca aaatatatta ttcataaaat acctcaaact gaaaactttt tcacgaatat
     3901 ttatttttca cctccccttt tttatttcac catgtaaatc gtaccataaa tatgcactta
     3961 tatgcaagaa aaaaatctat taatcgacag taaataatta gaaaaattca aattatattt
     4021 atcaagtata ttatataaaa tatttcctat gaaaatataa attaaattaa tgttcagaat
     4081 tgtttttaga tatgaaatct tgattttttt attactttac ttatttg
//
LOCUS       DAEQAF010000167         4099 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.171, whole genome shotgun sequence.
ACCESSION   DAEQAF010000167 DAEQAF010000000
VERSION     DAEQAF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4099
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.171"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            16..414
                     /locus_tag="KRN00_003519"
     CDS             16..414
                     /locus_tag="KRN00_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1829337.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIERGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            402..1340
                     /locus_tag="KRN00_003520"
     CDS             402..1340
                     /locus_tag="KRN00_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBH1829338.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(1724..1948)
                     /gene="secG"
                     /locus_tag="KRN00_003521"
     CDS             complement(1724..1948)
                     /gene="secG"
                     /locus_tag="KRN00_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBH1829339.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(2541..3833)
                     /gene="eno"
                     /locus_tag="KRN00_003522"
     CDS             complement(2541..3833)
                     /gene="eno"
                     /locus_tag="KRN00_003522"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBH1829340.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
BASE COUNT         1415 a          655 c          458 g         1571 t
ORIGIN      
        1 tcttaaggag ttgccatgat aaaaaaaata gaacatgtgg tcattactaa taataatata
       61 gaaaattata tcaattttta taaaaaattt ggtttttcat ctaaagaaat gagcaaaaat
      121 tataaactta atgctagaaa tgttaagata aatcttaaca taaaaggtta taaattttta
      181 ccttatgtta aaaattcaaa agcaagtaga gataacttat gttttaaaat aaacacaaat
      241 attgatgagc caaaaaaata cttagaacaa aatgagattc aaattgagcg aggaattgta
      301 gaatgtacag gtgtctttgg taatatgaaa tctatttatt tgaaaaaaac taatggaaat
      361 ttaattgaat tatcaaatca tagaatcacg gagagtaaac cttggaaaat ttaatcctat
      421 caataaatgt tgttcttcct ttgtttctca caatgtcact tggatatgtt ctaaaaaaat
      481 taggtctatt tgatactcat actttaaata aaatgaataa tgtctgcttc aagtctttct
      541 tgccattatt attatttttt aatatataca atacagattt agatggttct cttaatttta
      601 agcttatggc tgtagctgtt ataattattt tttcaatctt cttaatctta gtctttatta
      661 ttcctaaaat tgaaaaagat aataagacaa ggggtgcatt aatacaaggt gtatttcgta
      721 gcaatttcgt tatatttggt attcctgtga caatttcact atttggcgat aagagtattg
      781 gagtcacatc tttattaatt gcagttattg tacctatgtt taatgtatta tctgttgtaa
      841 ttcttgaaat ttttagaggt ggcaaagtaa atataaaaca tatgattaaa agcgtcttaa
      901 caaatccact cataatcgcc tcttttatag gattgacaat gctaatttta aatattaata
      961 tacctacatt tttacacaaa actattggtg atatttctaa aatagctact cctttatcac
     1021 ttataattct aggtggctct tttagttttt ctgctataaa ggggcatata aaccccatta
     1081 tattgggcgt atgtggaaaa cttatacttg tacctgctat atttttacca attagcattt
     1141 ttcttggatt tagaaatgta gaattagctt cacttatgat aatgttatct gctccaactg
     1201 cagtttcttc atttacaatg gcacaacaga tggattctga cagtgaatta gctggacaaa
     1261 ttgtagtatt tacttctgga ttttctataa ttacagtatt tttaataata tttattttaa
     1321 agcagaataa tcttatttaa tgatatttga taacacaaat tggtattatg agaaacatat
     1381 ataaaatcga tttaattgcg taaaaacata ttattatact atttttacta tataatataa
     1441 ctttgtgtat attatctcat taaacatggt gaaagtagtg ttgctatata ttttttagtt
     1501 tgaaaaaaat atataaatac aaacaatata taaatacaaa taataaacgc caacaaatag
     1561 tcaatctata aaataaaaac tggactaatc atataaaatc attagtccag cttttatttt
     1621 acgtactttt tatgttgatg tacttttatt aaaaactaaa tttaattttt aaatgtctag
     1681 caaatgcact aattaaataa tggccagtta ttcaacaata tcactacttc ttaactataa
     1741 gtaatgccaa tgcatttata aaaaataata ctgctgttat ctttgtaact ctagcaagaa
     1801 atgcttgttt tccttttggt ttaaagtaag cttgacttcc ttctccacca aattctgaag
     1861 gtaaagcatt cttagaatct tgaggcatta tgctaattac tagtaaaatc cctagtacta
     1921 cttgcacacc cattaaaatg ttgctcattc ttgcccctcc tatctgttta ttacttaaat
     1981 ttcattactc tttagtgtat cacaataata tagccatttc aagactatta tgctataaat
     2041 aacatacaaa aaaatatatt gttactataa tatattacta tattctcaat ataaaaatga
     2101 ataaaactta gaagagaaaa ctatttaaat taatacataa attaacactt aaaataatct
     2161 actctcattg tatatattat aaatagccac caaaataaaa caatcatttt aaaatattga
     2221 tataactttt aatttcaaca taatttaaaa taaataatcc acatttagca ataatacttt
     2281 aatgacaatt atgattaaat caaaatatgt cttcactttt attttttaat aaaaacctcc
     2341 tatgcaatta gataaaaatg agatagaaac atttattcat attttttctg aatctatgaa
     2401 taaaattaag taataaaata taaaaaagga taagtgaatt gaaaaatcaa ttaacactta
     2461 tctcttttat atcttataag atgagcttaa atatcttata ttctctcttc attaatcttt
     2521 tttagtaacc attttaataa ctattttttt aagttataga aagattttaa tccacaatat
     2581 ctagcttgct ctccaaccat ttcttctatt cttaataatt ggttgtactt agcaactcta
     2641 tcagttcttg atggagcacc agtttttatt tgaccagcat ttactgcaac agctaaatct
     2701 gctatagtag aatcttcagt ttctcctgat ctgtgagata taacagcagt atatcctgct
     2761 ctcttagcca tttctatagc atctaaagtt tcagttattg tacctatttg attaacttta
     2821 actaatatag agttagctac tccattttca attccttttt ctaatctctc tgtgttagta
     2881 acaaataagt cgtcaccaac taattgtaat ttatttccta atttttcagt taataatttc
     2941 catccatccc aatcttcttc gtctaaacca tcttctatag ttattattgg gaagttgttt
     3001 gaccaatctt catataaagc aaccatttca gcagcagtta actcttttcc ttctcctgct
     3061 aaaacatatt ttttagtttc tttgttgtac atttctgtag cagcaacgtc aagacctaac
     3121 ataacgtctt cacctggctt atatccagct tttgttatag cttcaactat taattctaaa
     3181 gcttctctgt ttgaacctaa gtttggagca aatccacctt cgtcacctac accacaagct
     3241 aatccttttt ctcctaaaac tttctttaat gaatggaata cttctgctcc cattcttaaa
     3301 ccttctttga aacaacaagc tcctactggt aatatcataa attcttgaac atcaacgttg
     3361 ttatcagcat gctctccacc gtttaatatg ttcatcattg gaacaggtaa ttgtttagca
     3421 tttactccac ctaagtattg gaataatggt aaacctattt catcagcagc tgctctagct
     3481 actgccattg aaacacctaa tatagcatta gctcctaatt tacctttgtt tggagttcca
     3541 tctaattcta tcatgattgc atctatagct ggttggtcaa atgcatccat tccttctatt
     3601 tcaggtgcta ttatttcatt tacgttagca acagctgttt ctacaccttt tcctaagtat
     3661 cttcctttat ctccatctct taattcaaca gcttcaaaag ctcctgtaga tgctcctgat
     3721 ggaactattg ctcttcccat tgctccatct tctaatacta cttcaacttc tacagttgga
     3781 tttcctcttg agtctaatac ttctctagca tatactaatt caataactga catttgtata
     3841 tctcccttcg attttctatt agttaaattt tcatttactg taaacatccg tctactattt
     3901 taatctactt tctatattat agtacataaa gttgcttttg aaaattaggt acaaatttat
     3961 ttgatgggta aatttgtaaa agttcctatt tttattttat tttttataat attttaattt
     4021 atataatata aaaaaacttg tctaaaatcc aaaaccaatc ttaaatacac aaatattata
     4081 actagattta aaacattaa
//
LOCUS       DAEQAF010000168         3979 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.172, whole genome shotgun sequence.
ACCESSION   DAEQAF010000168 DAEQAF010000000
VERSION     DAEQAF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3979
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.172"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            80..1033
                     /locus_tag="KRN00_003523"
     CDS             80..1033
                     /locus_tag="KRN00_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1829341.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFMFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNET"
     gene            1023..1979
                     /locus_tag="KRN00_003524"
     CDS             1023..1979
                     /locus_tag="KRN00_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBH1829342.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFVIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTNIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            1976..2731
                     /locus_tag="KRN00_003525"
     CDS             1976..2731
                     /locus_tag="KRN00_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1829343.1"
                     /translation="MIEIKNIFKKYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTEEDENCIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRGLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVEKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            2823..3788
                     /locus_tag="KRN00_003526"
     CDS             2823..3788
                     /locus_tag="KRN00_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBH1829344.1"
                     /translation="MNKKAAIVAAIAIIGLVTVFALGGSKKNESKTSENSNNTIKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDEKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFEVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT         1612 a          375 c          669 g         1323 t
ORIGIN      
        1 aattattatt gataaactat aaaagtaaaa atgataataa ttttcatttt gattaataaa
       61 agatttttaa ggagggagaa tgaaaaaaag gtatttagtc ataggaataa taattttgtc
      121 ttatttttct ttatttatag gagctgaaga tataaatata atgcatatat ttgcaaaaaa
      181 tcagcataag cttatgatat ttatcatgag tagaatacca agattaataa gtatattgat
      241 tgctggtgta ggaatgagca tagcgggtct tataatgcaa cagataagta aaaataaatt
      301 tgtatcacct acaacaggag ctacaataga tgcagctcaa tttgggatag tgatatgtat
      361 gcttttagta ccaactgcct ctatttttac aaagacaata atagcatttg tattttctct
      421 tgtagggact tttatgttta tgaaaataat agggaagtta caatttaaaa atataatctt
      481 tgtaccatta gtaggtataa tgtttggaaa tataataggt tctatgacgg actttatcgc
      541 atataaatac gatttgagtc aaaatgttag ttcttggatg caaggtgact tttctatgat
      601 acttaaaggt aattatgaga tattatatat cacaataccc cttataatat tagcatatat
      661 ttatgcaaat aaatttactg ttgttggtat gggtatggat tttgcgacaa acttaggtct
      721 tagttacaaa agaattgtca atataggtct gataatagta gcacttgtta cagtatgtgt
      781 agtcgttaca gctggtaata tcccttttat aggtctaata gttcccaata ttgtatcctt
      841 gtatatgggt gataatataa gagcaagtat atggtatact ggtttacttg gagcgatatt
      901 tgtacttata tgtgatattt ttggaagaat tattatttat ccatatgaaa tatctatagg
      961 gcttacagtt ggagttatag gaagtatact attcctttat ttaatattaa ggaggaacgt
     1021 aaatgaaact tagtctcaat caaaaaattt actttgtaag tatattacta ttcatatcaa
     1081 tagcactttt tgtaatttat ggaatagaca tgaatcattt agaatatgca ttatcacaaa
     1141 gaataccaaa aatatttgct atggtattag gtggaggatg tatagcattt actactgtag
     1201 tgtttcaaac aattacaaac aatcaaatat taacaccaag tgtattaggt ttagattcat
     1261 tatatgtaat gattcaaact ataatagtat tcatatttgg ttcaagcagt agtctgatta
     1321 taaatgaaaa ttataatttt attattaatg tagctatgat gattggagct tcattgttat
     1381 tatataagac gttatttgaa aaaaataaaa ataatatttt ctttttaatc ctagtaggaa
     1441 tgatatttgg aaccttattt aaaagtgcaa caacatttat tcaagtaatg atagacccga
     1501 atgaattttt agctttgcaa actaatataa tggccagttt aaacaatata aacactaatg
     1561 tattgttaat agcatttata ataattattg ccataatacc ttttatatac gatgaaataa
     1621 agtatttaga tgtattatcg ttaggtaaag agcaagcaat taatttaggt gtagattttg
     1681 ataaagcagt taaaaaaatg ataatattaa tagcaatttt agtctcaata tcaacagcac
     1741 ttattggacc tatgacattt ttaggacttt tacttgccaa tataacaaga gaaattttta
     1801 aaacatataa gcatacatac ttgatttcgg gttctatgtt gataggaatg attacattga
     1861 taataggtca attttttata caacatgtat ttaagtttga tacaacttta agtgtagtaa
     1921 taaattttat aggaggaatt tactttattc aattactatt aaagggggca aatagatgat
     1981 agagataaaa aatatattta aaaaatataa gaataaaaat gttgtagatg atgtgtcttt
     2041 tagtatagaa aagggaaaga taacatcttt tataggacca aatggagctg gaaaaagtac
     2101 agtactatca atagttacaa ggcttatagg aggtgatggt ggagaagtaa taatagaagg
     2161 aaaaagcttg actaattata gcaataaaga attagcaaaa aaaatagcta ttcttaagca
     2221 atctaacaat ataactttaa aacttacaat aagagaatta gttggatttg gaagatttcc
     2281 atatagtgaa ggtaatctaa ctgaagagga tgaaaattgt attgatgaag caatagaata
     2341 tatgaagttg actgatatac aacacaagta tttagatgaa ttgagtggag gtcaaaggca
     2401 aagagcttat atagcaatgg taatagctca agatacagag tacatattac ttgatgaacc
     2461 actgaacaat ttggatatga accattcagt acagatgatg aaggtactta gaggtctttg
     2521 tgatgagtta gataagacta tagtattagt aatgcatgat ataaattttg catcatgtta
     2581 ttcagataat atagttgcat taaagaatgg aaaagttgaa aaagtaggtc gtacagatga
     2641 gatagtaaat gaaaaagttt tagaagatat ttatgagatg aattttaaca ttaagaatat
     2701 aaatggaaat cgaatctgta tttattttta aaatattgta tataaaaata agcttgctat
     2761 atgatttttt gtaaaatttt taaattaaaa taaagattaa taggagagag gaaaatattg
     2821 atatgaataa aaaagcagca atagtagcag caatagctat tataggatta gtgactgtgt
     2881 ttgcattagg tggaagtaaa aagaatgaat caaaaacatc agaaaattca aataatacta
     2941 taaagataac tcataacttg ggagaaacag atgtaaaatt aaatcctaaa aaggtagtag
     3001 tatttgacta ttcggcttta gatacaatgg atgcattagg tgtagctgag aatttagtag
     3061 gacttccaaa agcgagttta ccagcatctt tagaaaaata taaggatgag aagtatgcag
     3121 atttaggagg cttaaaagaa ccagatttag aaggtataaa gtcagcaaat ccagatttaa
     3181 ttataataaa tggaagacaa gaagattttt atgagcaatt gtcaaaaata gcaccaacaa
     3241 taagtacaag taaagatgat aagaagtact tagaatctgt taaaaataat atagataaaa
     3301 tagcaaaaat atttgaagta gaagaaaaag caaatcaaga atttagtaaa attgaaaaga
     3361 aaatagaaac tttgaataaa aaagtaacag ataaaaattt aaatgcttta actataatgg
     3421 tgaatgaagg taatttaagt gtatttggtg aagaatcaag atttagtata ttatacaata
     3481 gttttggatt tgaaaataaa gataagaata taaaagaatc aagtcatgga caaaatatta
     3541 cttttgaata tatagctaaa caaaatccag aagttatgtt cgttatagat agaggaatag
     3601 ctactgggag tgatgtaaaa gaaagctcaa ctgcaaaatc tgttttgaac aatgatataa
     3661 taaaatctat ggatgcatat aagaatgata atataatata tttagattca ccaacatggt
     3721 atgtaaatga tggtggtctg acatctttaa ataaaatgat agatgatgct tcaaaagcgg
     3781 taaattaata atccaatata atcaaaatgt attttttata aaatgattat caaataaact
     3841 aggagttttt aagaactcct agtttatttt tgcataagaa agatatagtt taaacaataa
     3901 tattatttac aataagataa atctattcaa aatctaataa aatatgaagt tatactagac
     3961 aaaaagaata actcttaaa
//
LOCUS       DAEQAF010000169         3971 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.173, whole genome shotgun sequence.
ACCESSION   DAEQAF010000169 DAEQAF010000000
VERSION     DAEQAF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3971
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.173"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(182..1474)
                     /gene="brnQ"
                     /locus_tag="KRN00_003527"
     CDS             complement(182..1474)
                     /gene="brnQ"
                     /locus_tag="KRN00_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1829345.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGIK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
     gene            complement(2593..3885)
                     /gene="brnQ"
                     /locus_tag="KRN00_003528"
     CDS             complement(2593..3885)
                     /gene="brnQ"
                     /locus_tag="KRN00_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBH1829346.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
BASE COUNT         1369 a          675 c          443 g         1484 t
ORIGIN      
        1 gaatcttttt tattttatta tctttataaa tcatactact ccaaaaataa atttttaaat
       61 ttatcaaata ggattaataa tgttctttta tctacaataa tttaataatt cttttaaata
      121 taaaaaggaa ttgcctatat aatttaaagg caattccata attatcaatt agtttttatt
      181 attatgcagt tttactgctt ttagatggaa taaagtttcc tattattcct gctattacaa
      241 ctggaactat ccagttaaat cctaatgaag caaatggtaa gctattaact agaggaattt
      301 ttataccaaa acttgttgca actgttaata cacttactaa taatgccatg tatgcagcac
      361 atttgaacac gttgtcattt ttaattttat tactaaataa tgctagtata actagagtta
      421 tagttgctgg atataccata cttagtatag gagaagagaa ttgtattatt gtacttactc
      481 caaagtttga tatgattgca ctaaatacac aaactactat aactatatgc tcatacttta
      541 attttccatc tgtaagtgtt gagaaatatt gaccagctgc tgaagaaaga cctatagctg
      601 ttgttaaaca tgctaatgca actataatag ccaataaaat tttacctgta gttccaagta
      661 aagctgctgt tattgcaact attaaagctg tttgttgaac atcttgtcca tattgttgag
      721 acacagttgc tccaagataa cataatccac cataaactaa tgccattcct attactgcaa
      781 ttacacctgc acttattgtg gctttcatct tttctttctc acctgtataa cctttagcta
      841 ttactgacat gattataatt gatgcaaata cactagctgc caatgcatcc attgtttgat
      901 aaccttgagt tataccttct gcaaatacat tttgtattaa agaactgtct cttatttctc
      961 ctaatggaga tacgatacct ttaactatta atactgctaa agctataagt aaagctggag
     1021 ttaatattga cccaactata tctacaactt ttgatggtct tattgttaaa accaatacta
     1081 gagcaaagaa tactatagag aatattactg ggcttattcc agaacctatt gtaggtaata
     1141 tacccatttc ataagttgtt gctgctgttc taggtattgc taaaagtggc cctatacaga
     1201 ttaccattgc acatcctaat gcaatactta atcctttgcc tgctcttgag aacatcttcg
     1261 atgtgtctcc attgaactta gttgctgcta taactgctaa taatgccaaa ccaccatctg
     1321 caaaaaggaa tcctatgaaa gctactagcc aactacttcc agataaaact cctagatatg
     1381 gagggaagat taagttccct gcaccaaaaa acattgcaaa tagtgcaaat ccaattacaa
     1441 ttacatcttt aaaattgatt tgtttctcac ccatttaaag cacccccatt tgaattttac
     1501 taccttttac taaaaaataa gtccaatctc ttaattaaat gaaaaccttt tgacgagatt
     1561 ttatttaatt atacattttt gacttaaatt tgtcaattat gtttcataat ttataaaatc
     1621 ttcacaatat ttaatacaac tttcttaatt aaacaaaatc aacctgtata ctttaaacat
     1681 agttggtttt ttgttttttc tctaattttt cttgataaaa ttaactattc cgaataatta
     1741 aaatattaag actttttaga ttattcgatt tattattaag ttgtattgct ttatatactg
     1801 tatatatcac tctccttttt tacattcata taatcttttt aattcaattt aaattttaaa
     1861 tattttgtgt ttattatata atctgaaaaa aaagcagtca atagcatttt taattttttt
     1921 aattttcaaa attatgattc ttaaaaaatc gttttccttt tatcataaca cctatttacg
     1981 ttaattcttg tagtattttg tatttatttt gctaaattga cagttaactt tattcaattt
     2041 ttattctact tacgtaaatt tgcctcttgt tttttactct taaaaccatt ttttctgaaa
     2101 attccttatt atgatttatc aacttatttt tcttcataac aattactctc taacttccaa
     2161 cttacttaaa ctttgcagtt gctagtattc acgtttacat acttatatgt cataattaac
     2221 taaaaattct taatatatct ctcaatgaaa acaatttact catttattta atacatttat
     2281 ataatcatat gtcttaaatt ttgttttatt attttattat tgtcacaatt ttatttatat
     2341 tatatttttg taaaaatcat ttaatatgta tacttaaatt tataaaatta ctctaaaatt
     2401 cttttttaat ctctattatt gttaaaaaat aaaccatata tttttttgat attttcttat
     2461 actttttcca tattaaatac aaataattaa atatagaatc taaaaataaa aggagttatt
     2521 tgtacaaata actcctttta cttttagtta actcatttat ttacaattga ttatatttta
     2581 attaaacaaa acttagtttg ttccaagtgt attagattga ctctttgatg gtataaaatt
     2641 accaattatt ccagctatta taactggcac cacccagtta aatcctaatg aattaagagg
     2701 taaagaattt actactggaa cagctactcc ataactagat ataactgtta gtatacttac
     2761 aagcaatgac atatatactg ctcctttgta tacattatca ttcttaattt tttcattgaa
     2821 gaaagctaaa attattaaaa caattgatgg tggataaact atacttagta taggagatgc
     2881 tatctttatt atagttccaa caccaaaaga tgctactact gcactgaata cagatacagc
     2941 taatactatt ttttcataac tcaatttacc ttttgtaagt ctagagaaat attgacctgt
     3001 ggcagatgta agacctatag atgtagttaa acatgctaat gatactacta ctgctaaaat
     3061 cgctttccca acatttccaa gcaatccttc agttatattt actattactt gtgattgtac
     3121 tgcatctgtt ccatacattg ttgatacagt tgccccaagg aaacataatc ctccataaac
     3181 tagagctaat cctccacaag caagaacacc cgccttacca atcattttca acttgtcact
     3241 aatagtagaa tatcctttat catttaaaga tactattagc actgatgcaa gtgctattgc
     3301 tgcaaaagca tccattgtct gatatccttg acctatacct tctgcaaata cattaggtat
     3361 cataggttta tctactatat ctccaagagg tgatataata ccttttataa ttataaatgc
     3421 taaagctatt agaagagctg gagttaaaaa ctgtccaact atatctacga ccttagaagg
     3481 tcttattgtt agtacatatg aaatcgcaaa aaaaagtata cagaataata acactggaat
     3541 tgaagttcca aacaaaggca ttatacccat ttcataagtt gttgcacctg ttcttggtat
     3601 agctaagaat gggcctatac ataaaatatc tgcacaacct ataagaatcc ctaacttcat
     3661 accacatctt ttaaacattt caactacgtt tccatcgaat ttagctgtag ccattactgc
     3721 tagaagtgcc aatccagcat cagcaaacgt aaatcctaag aaggcaatta accattctgg
     3781 acctgtaatt attcccaagt aaggtggaaa tattaagtta cctgctccaa agaacattgc
     3841 aaataacgca aatccaaata ctataacatc cttggtctta cccattataa aatccccctt
     3901 tttaacctta ttaaattaat aaaatgtctc gattgtttac gcttgcataa gtaagttgaa
     3961 ttaaacaata a
//
LOCUS       DAEQAF010000170         3925 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.174, whole genome shotgun sequence.
ACCESSION   DAEQAF010000170 DAEQAF010000000
VERSION     DAEQAF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3925
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.174"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(3..776)
                     /locus_tag="KRN00_003529"
     CDS             complement(3..776)
                     /locus_tag="KRN00_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829347.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            complement(782..1669)
                     /locus_tag="KRN00_003530"
     CDS             complement(782..1669)
                     /locus_tag="KRN00_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1829348.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQIDIDSIVLRIVSEDIPSEDNIQPVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            complement(1683..2705)
                     /locus_tag="KRN00_003531"
     CDS             complement(1683..2705)
                     /locus_tag="KRN00_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829349.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFIAPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            3280..3456
                     /locus_tag="KRN00_003532"
     CDS             3280..3456
                     /locus_tag="KRN00_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829350.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
BASE COUNT         1409 a          605 c          373 g         1538 t
ORIGIN      
        1 agttaaaacc ttttgcttga tgtaaaattt tcatatgtta ttttagttaa cactatcatt
       61 aatataattg agattactat agaaaaaact atcaaaatac ttggtacatt gtacttaacc
      121 atttgttggc tcatcataat ccaatttgga gtcactgaca taaattttat agctttatct
      181 ggtataaaac ctacactaaa gtatggaatt gccattatca atccacctag tataaatgga
      241 attacagccg atttaaatat agatgaaagt gttaagccta tttgtgcaaa tataaaagaa
      301 gcaaaaatag tagtcaatat aacaattata tacatttgta ttactgtaag atttaaatta
      361 ctatttccaa agtaccataa gttatgaatc gattcattta aatttttaaa atcaaaaaaa
      421 ctaaaacctc taattcctac taacaatata aaagaaatat taataataga taaaattaat
      481 ccattagcta ctagttttga taatactact gatttttttc cctttttagt tgtatttatt
      541 aaacctgtca tattagaatc atattcttta atgtaatttc cagaagttat tataaacatt
      601 atcaaaccta ttagaggtat tgagccttct atcttgtaaa atatatctgc ataagtatct
      661 aaaacatcaa actttctaat cagaaaaaat ccaaaaaata ttaaaaacag ccaaattatc
      721 caaacactct ttgattttaa tatttttatc atttcagctt taactaaata catcatttct
      781 actacacctc ccttgcatct tccaaatcaa aataaaacat gtatacatct tcgaattttg
      841 cttgaactgg ttgtatatta tcctcgcttg gaatatcctc tgaaacaatt ctaagtacta
      901 ttgaatcaat atcaatttga atacttacaa ccttatattt agattgtata tcatcaactt
      961 cacattcatt tttaacttga acattatata ctttattttc catgtgactt aatatgtctt
     1021 tgtgtgttcc tttcattagc agtttgccat ctttaatcat tattgtttcc tttgcaactg
     1081 attctatatc ggaaattata tgagtagaaa gtattattat cttatctcta gacatttttg
     1141 ctattaaatt cctaaatcta gctctttctt gtgggtcaag acctgctgtt ggttcatcaa
     1201 ggactattat cttagggtcg tttagcaaaa cttgtgctat cccaactctc ctcttcatac
     1261 ctcctgagaa ttttcctata gacttatttc tcacatcata aagacctact aaatctaata
     1321 attctcctat cttactattt aaatattttc cccttaaacc ttttaaagct ccaatatact
     1381 gtaaaaattc ttttgctgta aaatttttat aaactccaaa ttcttgtggc aaatatccta
     1441 aaatatttct ataatcagca tccattttaa atatatcctc accattataa agtatctgac
     1501 cttcatcagg ttttatcaac gttgttattt gtttcattaa tgtagatttt cctgctccat
     1561 ttggtcctag aagaccataa actccatttt ccagagttac tgtaatcttg tcgtttgcta
     1621 cttttttacc atatatcttt gaaagatttt ctatttctaa tttattcatc ttaactcccc
     1681 ttttatctac ttatataatc tgattttatt actaaaaaac ataatgacat agcacctatc
     1741 aatattgcca tcaaaagtcc tattgctata ttgacaatgt ctatattcac tttaaatatc
     1801 ataatatcac ctagataatt tcctattatt ttattaaaac caaatatcaa atcataataa
     1861 tttacatttg atacaactga aagtaatttt ttaggtaata tatggattac cgacattatc
     1921 ttagttatag atataataaa tataaaaaaa cttattgaag atattgaaga cttacttata
     1981 aaagacccaa atatggctat catggcccat ccttcaaaca tcaaaagctc tatgcctata
     2041 tttaatatta catactttgt tatacttaaa ttagttttca atgcaactac attgtctact
     2101 attctaaaag attctaaatc tccattaaca ggtactcctt gttgcataca agttataata
     2161 aatattccca ttaaataaac agaataaatt actaatggaa ctaataaagc aacaaatatt
     2221 ttagacttta atgctttttt cttctctttt gatgatagta tgatatcttt taccgaagta
     2281 acgacttcat ctacataaat attggatata attatagata taataattaa cattcctaca
     2341 tttataagtg aatttgtgac tctatagtta aatactttcc aaaaactaat atccttatat
     2401 tcattcacac ttagattatc aagttttttc tttgacatta attcaatttt tttagaaaat
     2461 tcacctgtat ctgtttgatt tgaaaactgc tttaaaacat taatcttatt ttgaaatttc
     2521 tcattaccta tgtcgatacc acttctcgta tcttctatac gtcctttttc tttatctata
     2581 taataacttt ctgtttctaa aacaggcgca ataaagatac taatcattag tattaacact
     2641 aatatcccta gagatataaa catactctta gatttagcca atttttttat ttcccaattt
     2701 accaatatat ttctcctcct aaatcatttt aattacacat atatattaaa acttaaatct
     2761 tatataaata taatactaac cttaaataaa gcttaaatta ttttataatt tataggtgtg
     2821 tttattattg gagttacatt tattattttt ctgggaaatt atacattttc aattattttt
     2881 attatttttg atatttttat tgattggaaa ttttattgtt gttcaaattg tagttattct
     2941 ttaaatttaa agatggagtt ttttaagaat agaacctact gtccttatta tggaaagatt
     3001 attaaatagt tgcatataac tttatttatc ttgaatctta tttttaaaaa caattataat
     3061 tttagaatat tttctattct caaacaagca tgttgaataa tgaagcatct tctagtatta
     3121 tatacttgta gaataaaact aaattggtaa aactgggaat atttaacctt aaggagttaa
     3181 gttatagaaa ctagtactaa aaaattttat aaattatgtt aattgactaa tagaatgcga
     3241 ctttttattt ttactaaatt ttttaggggg atggataata tgtttattgg agaaatagac
     3301 aaatgtacac atatactaac tgcttacatc agtagttcat atgattattg taatttttta
     3361 gatacacagt tagatgattt tatatcagaa tatggagaaa cggtagttga aacctgctta
     3421 catcaagtct tattattagt aagtagatac aattaaaact aaatttttct agaaaaacct
     3481 ttttagattt atctactcta ataaatatat aattttttgt actttataaa taactataac
     3541 ttctgctaaa gtaaagatgt attgggagta catctttact ttcccattat agaagttaaa
     3601 agcatacacc ataaaattaa tcatccaata caaattatat atttcctatg tctaacttaa
     3661 tttacaagaa tcattctata tgcatattct gcaatccact aaacatggct ctaaaccttt
     3721 actattttat acattctcta taaatcatac aaatcatata taaaatcccc ctaatatgtt
     3781 taaaccacct ataaaataac accaatattt agaatattca atatcaactg cataactggt
     3841 caataaaaac gtataactag acaaatttca atatttatat aaataataca agagaaacaa
     3901 gcattttatt tacataagtt tttta
//
LOCUS       DAEQAF010000171         3771 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.175, whole genome shotgun sequence.
ACCESSION   DAEQAF010000171 DAEQAF010000000
VERSION     DAEQAF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.175"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            201..815
                     /locus_tag="KRN00_003533"
     CDS             201..815
                     /locus_tag="KRN00_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBH1829351.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDDSEYLRKS
                     VGNALRDISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            833..1195
                     /locus_tag="KRN00_003534"
     CDS             833..1195
                     /locus_tag="KRN00_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829352.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            1301..1798
                     /locus_tag="KRN00_003535"
     CDS             1301..1798
                     /locus_tag="KRN00_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBH1829353.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGD
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
     gene            2602..3720
                     /locus_tag="KRN00_003536"
     CDS             2602..3720
                     /locus_tag="KRN00_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBH1829354.1"
                     /translation="MIAVKKAYKFRIYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELNWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPKGRILNATISKEPSGR
                     YYVSLCCTDVDIEALENTNNHIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT         1512 a          418 c          638 g         1203 t
ORIGIN      
        1 acaactttat aatataaaac ttataataaa agtaaattta tatgttaaat gaggttgatt
       61 ttttattatt ttttatttat gctagtacta aagacttgca aacgtttttt gacaagtctt
      121 tattttgtct aaattaaaca aactttttta caaataaata cataaaattt aaactaatct
      181 atttattgga ggagataaaa ttggaagaag taattgcaaa aattattact atagaaaatg
      241 gattcaaaga aattgaaaac attgctaaaa aaattgtaaa aaataatgac tcaaaaaagt
      301 gttattatct atcaatctac ttatataggt cagaatatta tcaagtaaga gaattggctg
      361 tgtttatact tggttttata tcagtaacta tttctgaagc tttgttattt ttaaaagata
      421 atgtgagtaa agatgaaaac tggagagtac aagaaatact agctaaatca tttgattatt
      481 attgcagtga agtaggatat gaaaaggctc ttcctgttat aaaagaatgg cttaattctg
      541 atagtccaaa cataaaaagg gctgtgacag aaggtcttcg aatttggact agtagagact
      601 attttaaatc taatcctgac gttgctatat cactactttc tagtttaaaa gaagatgata
      661 gcgaatactt gagaaagtct gtaggtaatg ctcttagaga tataagtaaa aaatatccag
      721 atttagtaaa aaaagaatta gattcatggg atatatcaaa taaaaaagtt gagtttgtat
      781 ataagcttgc ttcaaaatgt atcttggcaa agtaaaatgg aggtgaactt atttgaaact
      841 tcgtgatgag tatacttgcc cattagaact aacacatgat atgataaaag gcaaatggaa
      901 atctattata ttatggagat tacgcatagg accaacttcc ttatcaaaac ttgaaaagga
      961 aatcaatggt attaatcaaa agatgttact tgaacaactt aaagaattaa ttgaatttgg
     1021 tcttgtagat aaaaagacat atgaaggtta cccacttaaa gttgaatact cacttacacc
     1081 tattcgaggg aaacaaatat tggatgcttt ggctataatg caagatatag gaattagctt
     1141 tatgttggat aatggtatgg aagatattct taaggaaaaa ggtgttttaa agtaaataga
     1201 tacccacaaa aaagtaagta atttaccatt attttcaact ggtatataat taaattatag
     1261 atatattcta ttaatttatt ataataggag gtaaattatt atgaaagtaa ctagtacagg
     1321 tatagtaaat ggtgttatag aagataaata tggtaaaaga ggaactcagt tcaatgaagg
     1381 tggtatgcct acatattcac tacctctaaa gtttgaagat gctccaaaga atacagtatc
     1441 ctttgctgta tttttagaag ataaagactc tgttcctgta tgtgggtttg catggataca
     1501 ttggttagct gtaaatataa caaaagatga gttaaatgaa aatgaaagtg taacagctac
     1561 tgattttgta caagggacta ctagttggca tggtaaacta ggagatcttg acagattaga
     1621 ggccagtgta tatggtggaa tggctcctcc agacagacct catgtctatg aaatacatgt
     1681 atttgcactt gatactatcc ttgaccttga aaaaggattc tatatgaatg aatttttcaa
     1741 agctattgaa gggcatgttt tagatacatt tacactaaaa ggaagttatt ctaattaatt
     1801 aggttgacta tagctaatca ttaattaaat gctacattta attgatgatt agcttaattg
     1861 ttattagaat attttctgca ctttatctta atatatattt tagttgactg gtattttaat
     1921 ttctattaga ttattatcaa tttatataaa ttgattaaaa aatagctacg cacactcgtg
     1981 actttagtca tgagttagta gctaaaatag tcagcatata gggaaactta tatgtagaga
     2041 taggatagaa cctatccaat actacttgaa ttgctaaaaa cccctaaagc taaccaaact
     2101 aaaacataag gatgaaataa acctaagtgt gaaagttacg aaagtagaaa aaattggtta
     2161 gatggtataa ggttaaaccc taagtacttt aaaatgggca atcagcaggt aaactccaaa
     2221 taggagaaac ttcaacgact attcctcttg agggaagtac actacaagtt atcggtagtg
     2281 gaagtgggta gaccttagcg gataatgccg aaggataaga tatagtctgt gcttatgtga
     2341 aagtgtaaga agttcataag agaactgcat aggtagtagc gaacttatgt gaacgacagc
     2401 ctcaaaaatg ataaaagtta agacttacgg ttcttatata tgttatttaa aattaaatat
     2461 aaaaccttct aaataattgt tttaaataat tacatttgtt aacattatta taggtgatta
     2521 ataaattgtt caccacagca ttatataata tattaaatat taaaatcatt aaaaagtgta
     2581 tcaaaaaaca attaaagtga ggtgatagca gtgaaaaaag cttataagtt tagaatatat
     2641 cctaataaaa aacagcaaga gttaattaac aaaacttttg gatgttgtag gtttgtatat
     2701 aataaatatc ttgctaaaag aatagatgtt tataaaaacg ataaagaaac ttttacttat
     2761 aaacagtgta gttctgattt aaccaattta aaaaaagaat taaattggct taaagaacct
     2821 gataaatttt cactacaaaa cgccttaaaa gatttagata atgcatataa aaaattcttt
     2881 aaagaaaagg caggatttcc taaatttaaa tcaaagaaaa ttaatagatt ttcatataaa
     2941 actaacttta caaatggaaa cattatgtat tgtggtcaac atataaaact acctaaactt
     3001 ggtatggtta aggtaaggga taaacaagta cctaaaggga gaatacttaa tgctactata
     3061 tctaaagaac caagtggtag atattatgta tcattatgct gtactgatgt agatattgaa
     3121 gcattagaaa atactaataa tcatataggt ttagatttag gaattaaaga attttgtatc
     3181 tcaagttgtg gagaatttat agaaaatcct aagtatctta agaagtcatt aaacaaactt
     3241 gctaaattac aaagagaatt atcgagaaaa acaattggta gtttaaatag aaataaagca
     3301 agattaaaag ttgcaagact tcaagaacat atagctaatc aaagaaatga ttttctacaa
     3361 aaactatcta ctaaattaat aaaagagaat gatattattt gtatagaaga tttacaagta
     3421 aagaatatga ttagaaatcg taaactatct cgcttaattt ctgatgtgtc atggtcagag
     3481 tttattcgtc aattagaata caaggctaat tggcatggta gacaaattgt aaaggtaggt
     3541 aaattctttg caagttcaca aatatgcaat aaatgtgggt ataaaaacga ggaagtgaag
     3601 gacttaaata taagagaatg gatttgtcct agttgtaatg aaactcacga tagagatata
     3661 aatgcaagta taaatatatt aaaagaagga ttaagactaa taacaattca aaataaataa
     3721 cgtatgtaag aaccgtagga actacgggga tagcctgtgg agaattagta a
//
LOCUS       DAEQAF010000172         3542 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.176, whole genome shotgun sequence.
ACCESSION   DAEQAF010000172 DAEQAF010000000
VERSION     DAEQAF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.176"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(258..623)
                     /locus_tag="KRN00_003537"
                     /pseudo
     CDS             complement(258..623)
                     /locus_tag="KRN00_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(644..1723)
                     /locus_tag="KRN00_003538"
     CDS             complement(644..1723)
                     /locus_tag="KRN00_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBH1829355.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELRGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            complement(1777..3066)
                     /locus_tag="KRN00_003539"
     CDS             complement(1777..3066)
                     /locus_tag="KRN00_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBH1829356.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     misc_binding    complement(3229..3440)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
BASE COUNT         1151 a          709 c          397 g         1285 t
ORIGIN      
        1 ttacctgctg attgcccatt ttaaagtact tagggtttaa ccttatacca tctaaccaat
       61 tttttctact ttcgtaactt tcacacttag gtttatttca tccttatgtt ttagtttggt
      121 tagctttagg ggtttccagc aattcaagta gtattggata ggttctatcc tatctctaca
      181 tataggtttc cctatatgct gactatttta gctactaact catgactaaa gtcacgagtg
      241 tgcgtagcta ttttttaatc aaactcatat ccaccagata ccaatattga atctaattct
      301 attttttctc ttaagtcttc tggccaatct ataaatggaa gaatggcagt agtggctggc
      361 tttcctattc ttatcatagc cacattatta agtctttttc tttctacaat agcatttgta
      421 caatgagttg taccaagcat agcatatttt attaatgaat ggtcaatctt actttcatct
      481 ataacttttt ttaaggcatt gtaaacacca gtttcaacat cttttgtagt tgccacctta
      541 actgaatgaa ttacttttaa ttccccatcc agtatacaag catctgtatt tgttcctcca
      601 acgtcaattc ctacacgata catcaaaatt tcctcctaaa cttttatttt ccttgtaatt
      661 cttctactgt tttatattcc acatcatatc caaagtatcc aggtccaact gtctcaattc
      721 ctttttctgt tctccacttt tcattacaag gaaaagctac taccataaca cgagagccat
      781 attttattct ctctgtagtt attggaaatc cagtttctaa atctaatact gctattaaat
      841 ctggtgtaat acaaagtggt gtatcacctt ttttggcaat taaattctca ttttggaata
      901 atatagaata ctctccatca tactcattaa tcccagcaaa aaaggcatgt cctctagtaa
      961 atccaccttt caactctctc ttaatatcaa ttacttttcc ttcaaataac ttgtatccac
     1021 gcaattcttt tagtatattc tcaacagcac cttttgaatc agatttattt tcaagtaaaa
     1081 accctcctat agtttcagct attgtaagag tattacctat agcagctttt ttaacttgag
     1141 ctccacttaa attatagtca ctaatagaag aacttcctcc catttctaca gttaaagttc
     1201 tagctaatct ttctgaccaa attccatcca caggataaag gatggcagaa ttaccttttt
     1261 catcagacat tacggcagga gatgcctcat atccttcaag ataaaaagtt accatttgag
     1321 cttcagggaa agctctaccc atagaatctg catctaagat aggaagtcct tttttagcag
     1381 caactgctat aggcataagt gagtttatcc ctcctatttc tataggaatt ataacatcca
     1441 cttttctatt taataatttc tccattattt ctaaaggggt agttaactca acttctgaaa
     1501 gtaatttttc tattgtaatt acaggagaac ccataccaga tactggaact accaaagcat
     1561 catcatcaag ttcatctaaa cttattactt ttacaggacc atacttttta atggcttgtt
     1621 ttgcaaccaa tttacctaca tatgggtcac ctccacctcc agttccaagc actgctgcac
     1681 caactgctat tttatctaca ctttcttctg ttaaaaatct catgttactt tctcctcata
     1741 tttctaattt attttatact ttataaacaa atttctttat actgctttgt ctatttcttg
     1801 cttatttttt gttgaacaaa gcacttttcc aataatagat tgtactacaa accctgctat
     1861 aaaaccatct aaaggtgcta tagtagtaag agttataaat ccatatgttg aaaggtaagt
     1921 tattaatata ccaattatcc aagacactat tgaacgttta actattggtt tatataatac
     1981 tcctttatca aagcctttaa gttcttgctt tactatgtaa tattctgctg tatatacacc
     2041 accaacaggt gcaattacaa ttccaagtaa atttaaaaat cctataaaac cttcatatat
     2101 tccaaataca gccaataatg ttgctataat accaaggact atagttaata ctttctcagg
     2161 agccttctta agtacaagag ctatacttaa tgatgctgaa tatacattac ttgtatttgt
     2221 agtccattgt gctaatgtaa gtactattat acctggtata gcaattccta atgtaataaa
     2281 aattctcata atatctgaag ttcccataca ttttactaat actatcgaaa ctattatcat
     2341 aaaagcattt ccaaattgta ttcccaaaaa gcttgaaaga gcacagtctc ttctactttt
     2401 agcccaacga cttatatcag gagatacaat tgcaccaact attattatac tcattgacag
     2461 agaaactcca cctgcaaatg tcatagtaga tttcatatta tcatcaactg aaattccatt
     2521 tgctctaaaa gctaagaata tagttagcat cataagaact aataaaaatg gtactgaata
     2581 cacactcaac ttctccattg ccttatatcc ataaattgca gtactcatca tcaagagacc
     2641 acctattagg cttaaaatct gcatacttac atctaaatta aatatatctt ttattattat
     2701 ctgtgcattt tgagcaaaga aacctacttg aactccaaac caacctaata gagaaacccc
     2761 tataactaga gaaaatattt ttgctccagc ttctccaaat acatactttg ttatcataga
     2821 tgtagataaa cttgtagatg aaccaaccaa agagcatgta gtatacaaaa ttgcagaaaa
     2881 aaatgaacca acaattactg acaatattgc ttgtttcatt ggcatactct gtgccaactc
     2941 agcgcctaaa ataacagatg ataaatccac acctattgct actaaaactg aaaacatagc
     3001 tacccaacca cgtttttgat tctctggaat ctgttccaga gcatagttaa ttttttcttc
     3061 ttccattttc atccctccat ttaaatcgta aaactactga ccttagcata ttttacaatt
     3121 ttctaattta taaatttatt aactatcata tttttataat tttcatttaa tatatagttt
     3181 taaattttct gaaataagtt tataataaaa aacgcctctt ggaaaaatcc aagagacgaa
     3241 tataaatccg tgttaccact cttattagta aaaattaatt ttactcactc attttcttaa
     3301 ggcgaattaa accactattc taacataatt acaatagtat tctccaaagt ccttttcaca
     3361 taaattccaa tattagttct cagccaaatc taactctctg taaaattcct ttatgctact
     3421 ttcttcttct acgaatatat aatattgatt tgtagttaat ttatgattta tatcataata
     3481 tatatgcaat attttgtcaa cttaaaaagt caattacttg cattttttag ttttatatgt
     3541 aa
//
LOCUS       DAEQAF010000173         3501 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.177, whole genome shotgun sequence.
ACCESSION   DAEQAF010000173 DAEQAF010000000
VERSION     DAEQAF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3501
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.177"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            156..494
                     /locus_tag="KRN00_003540"
     CDS             156..494
                     /locus_tag="KRN00_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBH1829357.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            960..1463
                     /locus_tag="KRN00_003541"
     CDS             960..1463
                     /locus_tag="KRN00_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBH1829358.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            1510..2469
                     /gene="moaA"
                     /locus_tag="KRN00_003542"
     CDS             1510..2469
                     /gene="moaA"
                     /locus_tag="KRN00_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBH1829359.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLIENKCSDTNRRMYEIGG"
     gene            2473..2943
                     /gene="moaC"
                     /locus_tag="KRN00_003543"
     CDS             2473..2943
                     /gene="moaC"
                     /locus_tag="KRN00_003543"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBH1829360.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            2979..3410
                     /locus_tag="KRN00_003544"
     CDS             2979..3410
                     /locus_tag="KRN00_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBH1829361.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMKGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
BASE COUNT         1465 a          301 c          664 g         1071 t
ORIGIN      
        1 atataattag ttaataaaac atattatttt atagtataga ttggttaata aaagtacaga
       61 ttggttaatg aaacattaaa ttacaatatt tgttaaaaaa attgtgagtt acatgatata
      121 atgtattaaa taggatacta aggagttgat atattatgtt aatagtaact acagaaaaag
      181 tagaaggtaa aaagatatca aaggttttag gattagtgag aggaagtaca ataagagcaa
      241 aacatgttgg aaaagatata ggagcaagtt ttaagaatct tgttggagga gaacttactg
      301 gatataatga aatgctcact gaagcaagac aaattgccat aggtagaatg gttgaagatg
      361 cagaagctaa aggtgcaaac gcagtaatag catttagact gtcttcagct tcagttatgc
      421 aaggggcagc agaaatgctt gcttatggaa cagcagttgt tttagaagat gataatagta
      481 ttcttgaaaa ataaaatata aatagttaaa aagaggcatc ttttaaaaat tttatggatg
      541 ccttttttta tttgaaaaaa ctaatttgag aagaaatttt aactattatg acaataaaat
      601 tagggtgata ttatataaat aagtaaaatt atattatata atgtatggta tagactttaa
      661 aaattttatt tgtagagaaa aatatggaca atgttataat aattatagaa attaaaagta
      721 cttacattca ttatgtatgt gacatgtata attagtttta tatttaatac agttttgaag
      781 taatatcttc attttgagaa cgttggaata ataaaaaatg tattattata ggtgatataa
      841 ataaaaaata aatataatat gttatattgc tgatagaaaa gagaataaaa gaaaataggt
      901 tttattaaaa gagattttta tttataggac ttaatcaatg tatagagggg tgagaacata
      961 tgtttaatgt tgcaattata acacttagtg ataaaggata tgaaggaaaa agagaagata
     1021 taacaggaaa aaagttaact gaatttgttg aaaatacagg agcttataaa gttactgaat
     1081 atgtacttat aaaagatgat aaggaaatgc taaaggaaaa tattataaga ctttgtaata
     1141 gtaataaaat agatttaatt cttacaaatg gaggtactgg tttttcaaaa agagatataa
     1201 ccccagaagc aactaaggaa gtgttggaaa aagaaatacc aggtctgagc gaatatatga
     1261 gaatgaaatc cacagaaatt actaaaaagg ccatactaag taggggtgta agtggaataa
     1321 gaaataattc tataataata aatttacctg gaagtcctaa aggtgcagtt gaaaatctaa
     1381 gttttataat tgatgtttta gaccatggca tagaagtttt aagaggagaa gctacagaat
     1441 gtgccactaa aaaaagtgaa tagtatataa tctagataga taaaaaatag acaaagaggt
     1501 agataaagta tgattgataa gtatggaaga aaaatagact accttcgtat ttcacttaca
     1561 gataagtgta atttaaggtg tgtctattgt atgccaccag atgtaaaatt tgataaaaat
     1621 tatataaatg aaaatctaag ctttgaagac tacaagttta ttataaaggc tatggctgaa
     1681 caaggtataa caaaaattag atttactgga ggagaacctc ttttatatcc taaattaaat
     1741 gagcttataa aatttacaaa agaagaatgt ggaataaata acataggaat gaccactaat
     1801 gctattggtc tttctgatag aatttttgag cttgaaaaat gtggcttaaa taaagttaat
     1861 ataagtttag attctttgaa ggaatataag tataaatccg taacaagagg aggaaactta
     1921 aaagatgtct taaaatcgat tgaatcttgt ttaaatttag gtataaaagt aaagttaaat
     1981 tgcgttgcta taagtgggtt taatgatgat gagcttaaag attttatgtt tttaacagtt
     2041 aaatcaccaa ttgatgtaag atttatagag cttatgccat taggtgaggc taatagagtt
     2101 tataagaagg gttattttaa tgtaaaagaa atgattgaaa aaatatatgg tttatataaa
     2161 gtcaaaaatg atgaaaaaag tacagcagaa tattatatgt ttaaaggagc taaaggaaga
     2221 ataggaatta taactccatt aagctgttca ttttgtaaca cttgtaatcg tattagactt
     2281 acttctagtg gtgcaataaa attatgtcta cattcaaaag aagaaataga tataaaacca
     2341 tttttacata aaccattgtt atttagagaa tctatgaaag atataataaa acaaaaacca
     2401 gaaaaacatc atttaataga aaataaatgt agtgatacaa ataggcgtat gtatgaaatt
     2461 ggaggataag taatgttaac acatataaat gaaaaagggt atgccaagat ggtggacata
     2521 agtgaaaaag atgatactaa aagaacggct gtagctacag ctacaattac tcttagtaag
     2581 gaagcattag aaaaagtaaa aaatggtcag ataaaaaaag gagacgtatt gtctgtagct
     2641 caagttgcag gtataatggg agctaaaaat acatcttcaa acataccaat gtgccatcag
     2701 attaaattag ttggatgtga tttagaattt gatgtagatg attctatgtc tgctattaag
     2761 atatacgcaa cctgtaaatc tcttgggaaa actggagtag aaatggaagc tttaaatgca
     2821 tgttctttag cagcacttac aatttatgat atgtgtaaag cagttgataa aaaaatggtt
     2881 ataagtaata tccatcttgt agagaagact ggtggaaaat caggagattt taagttcgag
     2941 taaattaata atatattggg ttaaaatttg gaggaaatat ggcgaaggta gtgtcaataa
     3001 atataagtga gaaaaaaggt gtaattaaag ttcctgtaca atgtgcagag ctaaaaataa
     3061 atcatgggat agttggagat gcacatgcag gaaactggca tcgtcagata agcttacttg
     3121 gaaaagaaag catagataaa atgaaaatga aaggctttga ccaattaaaa tatggagatt
     3181 ttgctgaaaa tgtaactaca gaagggatag aagttttttc cctgcctgtt ggtacaaagt
     3241 taagaatagg gcaatgtgaa gttgaagtaa ctcaaatagg gaaaaaatgt cacaatggat
     3301 gtgaaattaa gaaattgaca ggtgactgtg tgatgccacg agaaggaatt tttgtaaagg
     3361 ttctaaaaga aggaattata aatgtgaatg attcaataga tgtaatctaa tgaagtcact
     3421 attaaaatat aattataagt aaatactatt aagatttaaa tatatatttt aagagagaat
     3481 taattttaat aaaatatttt a
//
LOCUS       DAEQAF010000174         3498 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.178, whole genome shotgun sequence.
ACCESSION   DAEQAF010000174 DAEQAF010000000
VERSION     DAEQAF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.178"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..1574
                     /locus_tag="KRN00_003545"
     CDS             <1..1574
                     /locus_tag="KRN00_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBH1829362.1"
                     /translation="GTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMYNSY
                     TVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGINIIN
                     INKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRVSKSDVVVDAIFGTGLKR
                     DITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRGFLN
                     YDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGKVSI
                     VAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERLNKL
                     LNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWKNRF
                     VITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTYINP
                     TGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVNATD
                     LISNISLTMKELLDI"
     gene            1752..2198
                     /locus_tag="KRN00_003546"
     CDS             1752..2198
                     /locus_tag="KRN00_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBH1829363.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKADATVNVTNQ"
     gene            2219..3262
                     /locus_tag="KRN00_003547"
     CDS             2219..3262
                     /locus_tag="KRN00_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBH1829364.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
BASE COUNT         1418 a          330 c          671 g         1079 t
ORIGIN      
        1 taggtacatc taaattaagc agaaatgttg atactgcatg tgtagaagaa gtagggattc
       61 caatgattgt attgatggaa aatgcggtta tatctgcaat gaaaaatatg gatatagaca
      121 tgtataatag ttatacagtt gtatgtggtg ttggaaataa tggaggagat ggtcttggaa
      181 tagcaagaca tctaaataca tatggaaaag aagtaaacgt atttttagta ggtaatcttg
      241 aaaaactaag tgaatgctct aaaataaatt acaatgtact tttaaatatg ggaattaata
      301 ttataaatat taataaaaat gatttaagtg aaaaaaatta tggagatgaa aatgaagtag
      361 ataaaattat taaagttgag aaacaaaata ttataaaaaa taaaaattta acaattttta
      421 aagatagagt atctaaaagt gatgttgtag tagatgctat atttgggact ggattaaaac
      481 gtgatataac tggtattttt aaagaagtta ttgacatagt aaatgataat agcaaaaata
      541 catattctat agatattcct tcaggtatag atagcgataa tggaaatgta ttaggaactt
      601 gtattagagc aaacaaaacg attagctttg agttttataa aagaggtttt ctaaactatg
      661 acactagcac acttataggt gatgtagttg tagaaaagat aggtgttcca gattttatta
      721 caagaaaata ccatgatgaa gagttcataa ctgataagac ttttgtaaaa aataatatta
      781 gaagaagaga taagcatggt tttaaaagtg attttggaaa agtatctata gttgcaggtt
      841 caaaaggatt ttatggtgca agtttcatag caactgaatc tgctgttaag agtgggagtg
      901 gacttgtaac attaattagt agtgaagatg tgcaagaaaa ggtatctatt agacttacag
      961 aagcaatgac tttaaatttt gaagaagaaa gattaaataa attacttaat tctagtgatg
     1021 caattggttt tggtccaggt atgggagata atagtcaaac atttgataaa ttacttaaga
     1081 tagtagaaaa ttctaattgc ccaatagtat tagatgcaga tggattgaac gttatgaagg
     1141 acagatgtta taagttttta gaatggaaaa atagatttgt aattacacct catttgggag
     1201 aaatggccag gttgacagga gattcaattg ggtatataag agaacataga gtagatgttg
     1261 caaaagaatt tgctcaaaaa tataatctgg tggtgctttt aaaaggttat caaactgtca
     1321 taacagatgg taaaaaaaca tatataaatc ctacaggaaa tagctgtatg gcaactggtg
     1381 gaatgggtga ttgtttgctt ggaatgatta cttcatttat aggtcaaggt atggatatat
     1441 tggaagctac agttagtgga gcatatatac atggctatat aggagataaa ttgagcaaag
     1501 caatgtatac ggtaaatgct acggatttaa taagtaacat ttcattaaca atgaaagagt
     1561 tgttggatat ataattggtg atatttgata ctactttgta acaattttaa caaagtatgt
     1621 tgatataata ctattaatta attaattaat ttattttatt gttttgtaat ttaaatttat
     1681 attcaaaaac attgtataaa catataattt atatagggtt ttataattca tatgaaaaga
     1741 gggtagatag tatgaagtta atatggttga tagtagcagt cttatttgga atagcagaaa
     1801 tgttaacacc aagcttaaca ttgatatggt ttagtgtagg agctgtaata cttatatttt
     1861 taagtagctt tatagagagt attttcttac aaattttaat atttgcagta atttctatag
     1921 caatgttagt cgtagctact aaaaaaatag taaaaaaaga taaaggctat aaatctaaca
     1981 ctaatttaca agcaatgatg tctaaaaaag gtattgttac agaagagatt tctccaaata
     2041 acacaggtct agttgtagtt gaacatgaaa catggacggc tatttctata gatggtgaaa
     2101 agatagaaaa aggttctaca gtagaagtat taaaaattga aggggtaaaa ttagttgtta
     2161 aaaaagcaga cgccacagtt aatgtgacaa accaatagaa taaaggagga tttatagtat
     2221 gggtactaaa attgttttaa gtattgtatt aatagtagta gtcgtagcaa taagtttaac
     2281 ttgtataaga gttataaaac aatctaaagt aggtataata atgagacttg gtaagtttca
     2341 aaaagtggct gaaacaggtg tacatttctt aataccattt ttagataaaa tggcatatgt
     2401 aattgacctt agagaaattg taatagattt tccacctcaa ccagttataa ctaaagataa
     2461 tgtaactatg cagattgata cagttgtata ttataaagtt acagacccag ttagatatgt
     2521 gtttgagata gctaatccaa tagctgctat tgaaaattta acagctacaa cactaagaaa
     2581 tataattggt gaacttgatt tagatgaaac attaacatca agagatataa taaatgtaaa
     2641 aatgagaact attcttgatg aagcaacaga taaatggggt ataaaagtaa atagagtaga
     2701 gttaaaaaat ataatgcctc ctcaggatat tcaagttgca atggaaaaac aaatgagagc
     2761 agaaagagaa agaagagagg caatacttca agcagaaggt aataagtcag ctgcaatact
     2821 tcaagctgaa ggtgaaaaac aatctgctat attaacagca gaagccaaaa aagaagctat
     2881 ggtacgtgta gcagaaggtg aaaaagaatc tgctatatta gtggcagaag gtgaagctga
     2941 agctataaga cagacagcta ttgctaaggc acaaggtgaa gctgaaatga taaaaagaac
     3001 tcaaatggca acagcagaag gtttaaaatt agttttttca gcaatgaaag aggctgatat
     3061 agacaataat attctagcat taaaatctat ggaagctctt gaaaaaatgg ctgaaggtaa
     3121 gtcaacaaaa ctggttttac cttcagaagc agttaatttc ctaggaacat tcaaaggaat
     3181 aaaggaagtt atgagtgatg ataacaaaga agtacttgat ataaaagaag ttttaaatga
     3241 taatgaatca ttaaaaaaat aaaagagttt tgttatcata ggaaggatat ggaaattaaa
     3301 ggtcgaatta attaaatata gcacaaaaat gcacgttgaa aagaagagga cttataaatt
     3361 tttaagtctt cttctttgtt tttattagaa agatgaaatt ataaaaataa attaacagaa
     3421 tctttataca atttatcctt tactaatgta aaaagtgtta tataatatta tataaaacat
     3481 atagcaaata agcatggt
//
LOCUS       DAEQAF010000175         3439 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.179, whole genome shotgun sequence.
ACCESSION   DAEQAF010000175 DAEQAF010000000
VERSION     DAEQAF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3439
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.179"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            55..1065
                     /locus_tag="KRN00_003548"
     CDS             55..1065
                     /locus_tag="KRN00_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBH1829365.1"
                     /translation="MVYFVSIELKDRSLVNNQYKGKIKSANLSVDYEINQVMKDIDKL
                     GLNTVNVPIIINVESINSDIMSIDNNSKEKAIKLIKKLNKKGISTILEAYPWIENGKL
                     YETDWNPINKKRFFYTWQNTILNELIIDVANPLDVNVLNIGSNFVHLEEYQQNWGEII
                     DFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQKLNNNFFDKLDFISIAAYFELSNKP
                     VNTVDELISALHSSTVNNRGQNIKQEIYNLYKAHRKPIFFGELGFSNRESASSQPWNH
                     VPSKAVNGEEQARCFEAYKKVFENEDWINGFSVFCVGKIDDEKNFYPSKESIKVIKSW
                     YE"
     gene            1119..2243
                     /gene="wecB"
                     /locus_tag="KRN00_003549"
     CDS             1119..2243
                     /gene="wecB"
                     /locus_tag="KRN00_003549"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBH1829366.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENINSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKYSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            2321..3295
                     /locus_tag="KRN00_003550"
     CDS             2321..3295
                     /locus_tag="KRN00_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBH1829367.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT         1436 a          334 c          599 g         1070 t
ORIGIN      
        1 tttaaattaa aaagaagtat tttaatctca ttaataatct taatttttat atttatagtt
       61 tactttgtaa gtattgagtt aaaagatagg agtctagtaa ataatcaata taaaggtaag
      121 attaaatcgg ccaatttatc tgtagattat gaaataaatc aagttatgaa ggatatagat
      181 aaattgggat tgaatacagt aaatgtacct ataattataa atgtagagtc cattaattct
      241 gatattatgt caatagataa taatagtaaa gaaaaggcaa ttaagttaat aaaaaaatta
      301 aataaaaaag gtatttcaac aatattagag gcatatccat ggattgaaaa tggaaaattg
      361 tatgagactg actggaaccc tataaataaa aaaagatttt tttatacttg gcaaaatacc
      421 atattaaatg aacttataat tgatgtagca aatccactgg atgtaaatgt tttaaatatt
      481 ggttctaatt ttgtacattt ggaagaatat caacaaaatt ggggtgaaat aatagatttt
      541 gtacaatcca aatttgacgg tcttgtaacg tacagaacta attggtggta tacaaaaaaa
      601 gatgatttaa gtagtaagtt gttttatgaa caaaagttga acaataattt ttttgataag
      661 ttagatttta tatctatagc agcatatttt gagttaagta ataaacctgt taatacagtg
      721 gatgaattaa tttctgcctt acactcatct actgtaaaca atagaggaca aaatataaaa
      781 caagaaatat ataaccttta taaagctcat agaaaaccta tattttttgg agaattaggt
      841 ttttcaaata gagaaagtgc aagttctcag ccgtggaatc atgttccttc aaaagctgta
      901 aatggcgaag aacaagcaag gtgttttgag gcatataaga aagtttttga aaatgaagac
      961 tggataaatg gtttttctgt gttttgtgta ggtaaaatag atgacgaaaa aaatttttac
     1021 ccatcaaaag agagtataaa agttattaag tcttggtatg aataattttg aaagtgtaga
     1081 atttatatag attaaataga tgattaggag agatataaat gaatgacatc aaggttatga
     1141 ctgtatttgg aactagacct gaagctatca aagtagcacc tttaataaag gaacttgaaa
     1201 aaagagagaa tataaatagt attgtttgcg ttacagctca acatagagaa atgcttgacc
     1261 aagttataga aacctttaat ataaatgtag actatgattt ggatataatg gaaaaaggac
     1321 aaagcctgaa tgatataaca tgtaagattt taaataaact tcccttgatt ttaaacaagg
     1381 aaaatccaaa tataatattg gtacatggag atacaaccac aactctagct acaagtttga
     1441 ctgcatttta taataaaact cttgttggtc atatagaagc tgggcttaga acctatgata
     1501 aatattctcc ttttccagag gagttaaata gacaacttac aggtattatt gctgatatgc
     1561 actttgctcc tactaatttg gctagaaaaa acttgatttc tgaaggaaaa cctaataata
     1621 atatatttgt aactggtaat actgctattg atgctttaaa gatgacaata aaagaaaact
     1681 ataatcatcc tataattgat gagattggta acgataggat gattttgtta acctctcaca
     1741 gaagagaaaa tttgggtaaa cctatgaaaa atatattcag agctataaag cgaatagtag
     1801 atgactttga agatgtacag atagtatatc ccatacattt aaatcctaaa atacgaacta
     1861 tagctgatga gatatttgga aaatttcctg aaaaaattca tattatagag cctttagatg
     1921 tagctgattt tcataacttt ttaaataaat cttatatgat aatgactgat agtggaggaa
     1981 tacaggaaga agctccatca ttaggtaagc cagtccttgt gttgcgtgat aaaacagaaa
     2041 gaacagaagg aattgaagca aagacactta aattagtagg tactaatgaa gatagaatat
     2101 ataattcagt gagcgattta ttaataaata aagataacta tgttcagatg agtaaagcat
     2161 ctaatccata tggagatgga aatgcaagca aatatatagt ggatataata attaaaaaat
     2221 ttaattgcaa atatttaaat tagataaggc ctaaaacatt aactaattga tataagattt
     2281 atgataatat taaggaatac aatttttaag ggggagtaat atggctagaa aattaataaa
     2341 aaatttgggt aaaagtaaaa gtgtaaagag agtgaaactt ttatttaaga agatttttat
     2401 tactgtattc atagtagcaa gtatagttgc tatttttaat ataacgaaat attttgagga
     2461 attatacaaa gtaagggatt taaaaagtac taaaattgaa tactatatgg atgtggctga
     2521 tgaagcagga gatggaaagg tccaattaag ttggaaggcc ttacttgcta tagacatggt
     2581 aatacatgat gaagatttaa gtaatataaa aaagaaagac acattggata taggggaaaa
     2641 gtttatagta gaagataaaa atgataaagg cgaaaaggtg tataaggtaa aaaagtttaa
     2701 taaggtatta agcgaattga aatttgactc ttctcaaaaa agtagagcaa gaaaatacat
     2761 gaaagattta gaatacacat accttggaaa taaacaatta gatagtagtg atgaaaaaat
     2821 taaatttata aagaagttag aagactcagc tataagagaa tatattgatt atggaatatt
     2881 gccctctata acaattggac aagctatatt agaatctggt tggggaaatt ctaaacttac
     2941 aaaacagagt aataatttat ttggtataaa agcagataaa gcatggaaag gaaaaagtgt
     3001 agaaatttca acttcagagc attataatga aaaaattgta gctagtttta ggtcgtataa
     3061 ttcattacaa gattctgtca aagaccacag tttattttta attaataata aaagatatag
     3121 aaaacatggg ttgtttgagg caaaagatta tattagtcaa gctcaatcat tagaaaatgc
     3181 aggatatagt acagcagaag ataaaaaagg aaatcgtata tatgcagagc tattaataga
     3241 tgttattagg agttataatt tgcaattgat agataataaa gttgagacaa aataattgtt
     3301 aactttaata tgaggagata acaagataag attcttttct acaaaaagaa tagaaaaatt
     3361 gtaaaaaaaa ctaaaaaaat gtattgactt gttatttaaa aggtgatatt attattactg
     3421 tactcgaaag agaacaaaa
//
LOCUS       DAEQAF010000176         3416 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.180, whole genome shotgun sequence.
ACCESSION   DAEQAF010000176 DAEQAF010000000
VERSION     DAEQAF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3416
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.180"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(292..1563)
                     /locus_tag="KRN00_003551"
     CDS             complement(292..1563)
                     /locus_tag="KRN00_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBH1829368.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIILEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     gene            1775..2014
                     /locus_tag="KRN00_003552"
     CDS             1775..2014
                     /locus_tag="KRN00_003552"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829369.1"
                     /translation="MECYLKRTLVIFSEAFLSISFKTRKYLFIVIFILVCPNLSEMIF
                     ILVPARRRIIRIDNIVSIYKYIGVLKLINYSILIL"
     repeat_region   2210..3229
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=2210..2238
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
BASE COUNT         1244 a          411 c          452 g         1309 t
ORIGIN      
        1 ttagatatat cattgtaaat taacatagct ttgaatataa taatgttcag aaggcaatat
       61 ttttgaggtc tgaatccaat aataatatag tcttatgatt gtagatatca aaaaatgtaa
      121 gttactagga atacgttttg tagatttata tatgattaat aactaaagct ataaataaac
      181 aaaataaaaa gagtatgttt caacctatag cttttagatt taaaatatac tcttttatta
      241 attatagttg tataaattaa ccctaatata taattaaaat ttttattata attatatatt
      301 aggttcttca attagttttc cacatacata tctatgaatg atatttctat catcaccaac
      361 atagataaat ctttcaagtc tttcaagtat agaataattg tcatgattta aatttgaatc
      421 atcaataatc aatgcatcaa aatcatagcc ttcttcaaag ctaccaactt ttccaaagaa
      481 acttccacca cttttggttg caatataaaa agcctcagat aaagataaga aattatactt
      541 cttaccagaa ttaacccaat ataatttaga taattgtatt gcagatacca ttgctttaaa
      601 tattgacaat gtatgtccac cgcttatatc tgatccaagt gctaatctaa tattattatc
      661 gattaatttt ctgataggca tagcaccact accaacatta aagttagaag ctggacagtg
      721 aactgccata acattatttt ctctcattaa atctatttca tcctgagaac aatgaacaca
      781 atgagccatt aaagtaggag tttgaccaaa taaattatat ctattatatg catctccata
      841 gaatttagat tcaggttcta gacttctaac ccattcaatc tcatcataat tttcagataa
      901 gtgtgattga ataggaatat tatattttaa acataaatct cctaaacctt ttaaaagttc
      961 acttgtacag cttggtataa atctaggtgt tattattggt tttacaatag aatctgtatc
     1021 actatactta tttataattt cttctgtatc agtaatagaa tcctgagtgt tttctaataa
     1081 agtatcaggg caattcatat tcatatttac tttaccaacg tatgctccaa gaccaacttc
     1141 tttgaatata tccataagtt tcatagaggc ttctttatgt actgttgcaa acactgctat
     1201 tcttgtagtt ccagatttcc aaagttcttt tacaaatttt ttatacattt ttgttgcata
     1261 ttctatatct ttataatttg attcttctgg aaatgtataa gtttcaagcc atggcaaaag
     1321 ctctttatcc atagccattc caagattttt aaattgagag gcatgggcat ggaggtcatt
     1381 cataccaggt attataagct tatcagtgta atctactact tttaggtttt tgtattcctt
     1441 aggtatctct ttaaatattc cctttacttt acctttttcc agtataatat aactattttc
     1501 aaatactgtg aaagtttctg aagtttttgt aaaaattata tttcctttta atacttttaa
     1561 catataggtc tccttagttt taaatttgtt ttaatatatg taggtaaaat tttgttttac
     1621 aaatcaaaat tttaccacat gtattatatc aaatctaaac tataaatact attagataat
     1681 agcaaatatt agtgaaatac agttgtttac tattattata tataactgac atttaagtga
     1741 catttaagaa aaatataatg cctacttaca taaaatggaa tgttatttaa agagaacttt
     1801 ggttatattt tcagaagctt ttttatccat atcgtttaaa acaagaaaat atctattcat
     1861 agttattttt atattagtat gtcctaatct ttcagagatg atttttatat tagttccagc
     1921 tagaagaaga attattagaa tagataatat agtaagtatt tacaaatata taggtgttct
     1981 taaattgata aattattcca ttttaatttt atagtttgag ttttatgata taataaaaat
     2041 atataaattt tgcagtgagc gatatttttg ataaagtagg gtttaacagt tgcaatgtaa
     2101 gggattgagg gtgtatgata aatgttatca attgcactac tcatggttca ctgcaaattt
     2161 gagagagttg tatgtgtata agtactgaaa atacttagtt tattttgggg ttttatatta
     2221 actaagtggt atgtaaatta ccaagtataa acagcaataa aaatagaaat aggaagtttt
     2281 atattaacta agtggtatgt aaatggaatt acaatattat ctccaacagg caaagaagga
     2341 ttgttttata ttaactaagt ggtatgtaaa tcgataaaac taagccaaaa aaggctttga
     2401 acgttcaagt tttatattaa ctaagtggta tgtaaataca tttgaagaac aaaacttaga
     2461 cttttataac gcacgtttta tattaactaa gtggtatgta aatatataag caggaaataa
     2521 accagccttt tttgctaatg gttttatatt aactaagtgg tatgtaaatc ttgctggatt
     2581 tgaatttaat atagaatttt ctcaggtttt atattaacta agtggtatgt aaatagtcat
     2641 tgtttgttat gtttatctta ttaccctgta agttttatat taactaagtg gtatgtaaat
     2701 ataaacataa aaaacattga tagtaatata tactatgagt tttatattaa ctaagtggta
     2761 tgtaaatagc tacttaaaca catcagtaat ggcaaattat ggggttttat attaactaag
     2821 tggtatgtaa atcaaattgc tgacaacact gaaagcatta tgaacgctag ttttatatta
     2881 actaagtggt atgtaaattc tggaatatga gaagtttctg tagtaccata aagtgtttta
     2941 tattaactat gtggtatgta aattagaaaa taacgtcagt agtattagca ggtaaatcta
     3001 aagttttata ttaactatgt ggtatgtaaa taacacttta aaaactaatg tattcagtat
     3061 aagagattgt tttatattaa ctatgaggta tgtaaatctt atacttagtt agaactatat
     3121 atcgacacaa atatgcttta tattaactat atggtatata aattgcaatt tttattcgtt
     3181 gtccaatatc tttgaaattt gttttatatt aactacgtgg tatgtaaatt tgcaacaagt
     3241 ataggtaaaa taccccaata atttatacag cattttctcc tttaaaatat aattattttt
     3301 tagcatttgt agtaaataat taccagataa cattgacttt agttttaatg attaaaatat
     3361 aaaagtagaa taattataaa aagtattgaa aaatttatac atatatataa taaaac
//
LOCUS       DAEQAF010000177         3328 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.181, whole genome shotgun sequence.
ACCESSION   DAEQAF010000177 DAEQAF010000000
VERSION     DAEQAF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3328
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.181"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(56..628)
                     /locus_tag="KRN00_003553"
     CDS             complement(56..628)
                     /locus_tag="KRN00_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBH1829370.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(657..923)
                     /locus_tag="KRN00_003554"
     CDS             complement(657..923)
                     /locus_tag="KRN00_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBH1829371.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            complement(923..1132)
                     /locus_tag="KRN00_003555"
     CDS             complement(923..1132)
                     /locus_tag="KRN00_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBH1829372.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            1401..2261
                     /locus_tag="KRN00_003556"
     CDS             1401..2261
                     /locus_tag="KRN00_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBH1829373.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            2309..>3328
                     /locus_tag="KRN00_003557"
     CDS             2309..>3328
                     /locus_tag="KRN00_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBH1829374.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVN"
BASE COUNT         1286 a          379 c          544 g         1119 t
ORIGIN      
        1 aacacaacag taaattataa attatcaaat aataatagtt atacaaataa aaattttaga
       61 acattttttg agattcttct aactcgtaag catccattaa agcttcacca aatctttgat
      121 agtgaattat ttctctttga cccaagaatt ttaatacatc tataacatca acgtcatctg
      181 ttaggtttat aagttgataa taagttgcaa gtgctttttg ttcagctgcc atatcctcat
      241 gtaaatcggt tacgggattt gacataactg ctataggtct tacatcaaat ggaacaccat
      301 ttgaatctgt tggataaatt ccatatccat tttgagcata gtttgaacca agacctgcag
      361 cttttaactc ttctgggctt gcatcagaag ttaactgata aaccatagta catataagct
      421 caacgtgagc tagttcttct gtaccaatat ctgttaaaag tgcacgcata ttaccagtag
      481 gcattgtata tctttggctt aaatatctta aagatgcagc aagttcccca tttggcccac
      541 caaattgagt tataagaaat ttagccattc tagggtcaca agtttttata ttaactgggt
      601 gttgtatagt tttctgatat atccacatga attttcaatc ctccaatact tgatgtctaa
      661 taattaaatt ctctgtccca aggccaaggt tggtcagccc attgccaagg gcatctactt
      721 ggagcatacc caaagttagt taaaggaccg tatttatttt cgtaagcata tctagcttgc
      781 gcaaattgat tacataatga attataagtg ttgatagcat ttttatcatc agggtgattg
      841 tctaaatata agttcatatc aacacatgca aaagatgttt cctgaacttt tctcataagt
      901 tcagctctag atgagtcttt cattatcttc tacctcctct atattttttt ggcttagcat
      961 ataattcttt gttgtacatt tcagactcta gtaagtttag ttctggaaat atagttccaa
     1021 attttaatgc atcagaaagg cagtacattt ctgtgaaaat ttgattatta atgtatggtc
     1081 tagccaaaga tggaccacaa ttttttttga tatctctagt cttattttcc aagatgaaaa
     1141 cctccttgtt gtaaatagat aggtaactct atctagtgta taatattcaa tcatttaaaa
     1201 atcgttacta ataataaaat attaaatgag aaaaataaaa aagataataa aagaaagagg
     1261 ttatttatgt tattataagt ttatgtgtta ttgtaaacta taaattattt agtaaaatta
     1321 aagtaaaaat tatagtattt tgtggatgaa ggtagacttt tttgtaaaat attattaaca
     1381 taaatatacg aggtgattag atgagtgaac tatcaggaaa aggctgtgaa attatagttc
     1441 cttttgagga aagacttcca gtaagagata tagaaaaaag tataataaaa aaatatagga
     1501 aaaatttatg gtctaagttt atgaaggcaa taagagatta taaattggtt gaagaaggtg
     1561 ataagatagc tgtagcgatt tctggtggaa aagacagtat tcttatggct aaaatgtttc
     1621 aagagttaaa aaaacatgga caagttaatt ttgatgttga atttattgct atggaccctg
     1681 gatatcatgc aaatataaga caattactta tagataattg tgagtatcta aatataccaa
     1741 tacatttatt tgattcaagg atatttgaga tagcagatga aatagcaaaa gattatccat
     1801 gctatatgtg tgcaagaatg aggagaggag cattatattc aaaggcagaa gaattagggt
     1861 gtaacaaact tgcattaggt catcattatg acgatgtaat agagacaaca atgcttaatt
     1921 tattgtgtgc tggaaatttt aaaacaatgc ttcctaaact taattctact aattttgaag
     1981 gtataaaaat tataagacca ctttattata taagagaaga acatattata agatttattc
     2041 aaaatagtgg tatatggcca ttaaattgtg catgtatggt tgctgctaaa aaaacaggta
     2101 ataaaagata tgagataaaa gacttaataa agagcttaga atcaaatttt aaaaatgtag
     2161 aaaaatctat atttaaggcg gcagaaaatg taaatcttga ttcagtactt ggttggcaaa
     2221 aagatgggga gaaacattct ttcttagaaa attttgaata aaaatagtta aaaagaatca
     2281 ctataaacaa ttggaaaggg tgtttatatt gaaaagagta tatatagatt ttgaaatgaa
     2341 tatgccaaat tctaaatcaa aaagagcagt atttaattct gatataattg caatcggagc
     2401 agttatgtat gatgaaaaaa caaaaaatat tgataaattt aaatctttaa taagaccagt
     2461 aagtaatgag gagttgtatc ctcatataca agaattaaca catatatctt ctgaagaatt
     2521 gaagagtgca ccaagttatg aagaggtcat gagaaagttt aaaaaatggc ttggcatatt
     2581 ttctgatatt aaaggaatat atacttttgg taatttggat ttgacatgtt tcaataacac
     2641 agatatgaga agtgctaaaa aaaataacca tccaaggttt gtaaataaca ttagagattt
     2701 atttgtagat ataaaagaaa aatatataaa ttgtggtatg agatgtatga actatatatc
     2761 attgaaaaat ttacttgaat ttgttaactt agagtttagt ggagatgccc atgacccatt
     2821 aaatgatgca tataatttat ttattttgga tgaggcaatc acaaataatg tagatataca
     2881 aaatctttta ataatacgtg acataataag accaccattt aacgatataa attctaattt
     2941 agataattgt tttaacaaat ttaaggagtc attatataaa aaagaaggaa attataatat
     3001 tgtagatttt tctgttgaaa taataaaaac tgtgagaatg tacttattaa caatcataga
     3061 tgtaaatata caaaatttag aaattatgaa agatataagt aaaaaaatgg atactataga
     3121 taaattgaaa gatatagagg aaggctattt ttatttatta gaagatgtgt acttcgatat
     3181 gaaagatgta ctagaagatt taatgcttta tagaatgaat gaagatgagt acaagtatga
     3241 gataaaaaat ataataaaaa tgtttgatga agacttagat aatgaaaaaa tatatataaa
     3301 taaatgtaat aacttaaatg ttgttaat
//
LOCUS       DAEQAF010000178         3259 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.182, whole genome shotgun sequence.
ACCESSION   DAEQAF010000178 DAEQAF010000000
VERSION     DAEQAF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3259
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.182"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            52..663
                     /locus_tag="KRN00_003558"
     CDS             52..663
                     /locus_tag="KRN00_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBH1829375.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            961..1299
                     /locus_tag="KRN00_003559"
     CDS             961..1299
                     /locus_tag="KRN00_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBH1829376.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(1705..3141)
                     /gene="miaB"
                     /locus_tag="KRN00_003560"
     CDS             complement(1705..3141)
                     /gene="miaB"
                     /locus_tag="KRN00_003560"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBH1829377.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT         1119 a          477 c          377 g         1286 t
ORIGIN      
        1 tgttaaaact caattatata atttttaata atattatttt aggaggtaaa aatgataaac
       61 gatattaaaa ataaattcaa aaattacaaa ccatatataa atggatacaa gaatatgaag
      121 agagcatctg ttttaattcc aatagtagaa ataaataaca cacactatat attatttgaa
      181 gttcgctcaa aaaatttgaa gcatcaacct agcgaaattt cttttccagg tggtaaaata
      241 gaatcaggtg agactccata tgaagctgtt attagagaaa cttgtgagga acttggaact
      301 tttagtgaca atatagaagt aatatcaagt cttgacctcc ttataacacc agtaaagttt
      361 atcatacatc catacttagg atatataaaa aatattaata atttaaatat aaacaaggat
      421 gaagttgacc atactttttt ggttcctata aaatatcttt tagagaatcc tccaaatact
      481 tatagtaata ctgtaaaagt ttttccagat gaaaatctac catatggttc aattccaaac
      541 caaaaagatt ataaatttga aagtggaagt tatcctattc tgttttataa atataaagat
      601 tatgtaattt ggggaatgac agcaaaaata ctagaaaact ttttaaattt tttatcagaa
      661 taacactcat aataaattat caaaactttt acataagaaa tttataaaag tttctaaatt
      721 taacaattct aaaatatcaa taactatatt ttgtagcact tttttatttt attattgttt
      781 gaatatttga tggttttcaa tgcaatttca acataaatac tatgtattag tgtatactgt
      841 tgatgaatta aagtatgata atctatttaa taaagtatga agtaaatgat tttaatgtgc
      901 ctttatggta aaattactaa taagtaataa aattaattaa aatatatgga ggtgcttata
      961 atgtttgctg taggatttgt tgttataatt gcacttgcct ttttcatttt aagtgtacta
     1021 ttatttaatg gaaaagccag tatgctacta gcaggttata actctatgag taagaaagaa
     1081 aaagcacgat acgataaaaa aaaattatgt agaagttcta gcattgttac ttttattgtc
     1141 tctataatgc tatttattat ggcgtttttg ggatatagaa tagagagtgg tcaaatggac
     1201 gaaaaaaaaa tggttccctt ttctataata tttataatag tcatactttc cagtgtattt
     1261 tttaatatcc tctactctaa caaaaaatgt aaaaaataaa tagttgtaag ttgagcagtt
     1321 aattataaaa gattgactgc tttttcatgt atattgacta ctcttattaa atattttaac
     1381 atttaaaatc tatgtaaaaa taatgaatat agtacaaact tctaataatg attttacctt
     1441 tgtggttaca gtccactata tataatttaa tatgataaca gggaattact aatgacaact
     1501 aggtaagctt ttataaaata taataaaaca aaaatagatg tacaatgaaa ttatatctta
     1561 tatcaaattt atttttatta atagcaaaaa cttacattag cataacatat gacaaattcg
     1621 cttaaaataa aaatttttaa tataatttgt tctatagtac atctattttg attagtttac
     1681 ataattttat tattttgtac aatattaatt atttactaat atcccattta atgaaaaagt
     1741 tctaggttca gtaattttga ccataactag cttaccaatt aaatcatcat ttccaccttc
     1801 gaaatttacg agtttatttt gtctagttct accagcaaac ttattttcat tatttttact
     1861 tcttccttca actagaactt caactattct atctttatat ccatcattta tttctgcaga
     1921 aatcctattt acagcttcta acaccctatt aaatctatca tgctttatat cttctggtat
     1981 ttgattttcc attttagcag caggagttcc ctgtctttta gaataaataa atgtaaaagc
     2041 tgaatcatat ctaacttttt caaccacatc taaagtgtcc aataaatctt cttctgtttc
     2101 tcctgggaaa ccaatcatta agtctgtaga aaaagcaata cctggaactt cctttttagc
     2161 tttttctatt atttctaaat aatattcctt tgtataatgt ctattcattt ttttcaaaag
     2221 gctactgctt ccacattgta ttggtagatg taaaaactcg cacaccttat cacaatctct
     2281 aattgcgtat attacttcat cagatatatc ttttggatga gatgtcataa atcgaaccct
     2341 ttcaattcct tctatatcat tcacttttct taaaagttct gagaatgaaa ctggattttc
     2401 aagtgtctta ccataagaat ctacattttg tccaagtaaa gtgatttctt tcgttccatt
     2461 tgcaacaagc tcttttatct cgttaattat atcttcagga gttctacttc tttctcttcc
     2521 tcttgtgtat gggactatac aatatgtgca gaaattattg catccataca ttatatttac
     2581 aaatgctttt aattcaaatt ttctattact tctaagacct tctattactt ctccatccac
     2641 atcccataca tccactaaca ttttgtcaga atttattgat tctgtaagta attgcggaaa
     2701 tttatataga ttatgtgttc caaatataag gtctacatgt ttatattttt ttcttaattc
     2761 ctctacaaca tgtggttgtt gcatcataca tccacataca gctattttca tatctggatt
     2821 ttttcctttt agatgtttta attgtcctaa gttaccatac acttttagct ctgcattttc
     2881 tctaactgca caggtgttat atattattaa atcactttct tcaaccatca ttgacatttg
     2941 gtatcccatc tcttctaaca ttgaacataa tttttctgaa tcatgttcat tcatttgaca
     3001 cccgaaggtt tgagtaaaca cgagttttct ctttccagtt ctgttgaagt attcttcatt
     3061 ttgtctgtgt atttgttcta tatatttatc ttgttcttgt attttctcta taggtattgt
     3121 tacttgtttt cttttgctca cgtctattcc tcctagttaa tttcttatat tacacataac
     3181 cttaattata tcaaataaga aaaatctttt aaagatatta ttatttttct agttgtgttt
     3241 taatagtaaa tctaatgat
//
LOCUS       DAEQAF010000179         3232 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.183, whole genome shotgun sequence.
ACCESSION   DAEQAF010000179 DAEQAF010000000
VERSION     DAEQAF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3232
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.183"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..522
                     /locus_tag="KRN00_003561"
     CDS             <1..522
                     /locus_tag="KRN00_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829378.1"
                     /translation="ALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQMIKSLGINIGSI
                     KILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGITLFKKFTFIKDT
                     TAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNISLKKNKYKASTK
                     NKSEKRGVVDVTN"
     gene            509..1264
                     /locus_tag="KRN00_003562"
     CDS             509..1264
                     /locus_tag="KRN00_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003399531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBH1829379.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQITLDSTTITNLAEYKRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLKKCLRHKTNDLEHLLEGISLDLKKYLDIKVQYLSGGQRQSLSLIM
                     SSLASPKVLLLDEHTAALDPKTSNEVIELTDKIVREKNITTLMVTHNLKHALQYGDRL
                     IMLHKGEVVLDVKDKEKEDLTVEEILEKFEYAV"
     gene            1361..2398
                     /locus_tag="KRN00_003563"
     CDS             1361..2398
                     /locus_tag="KRN00_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1829380.1"
                     /translation="MIKSKKILSLIIAGVLGVSMLTGCSQNDGSNASNENKETDSKKQ
                     KNIGISQLVEHPSLDKAKKGFIKALEDKGYKDGDNIKIDFQNAQNDMPTTQSIASKFV
                     SDKKDLIYAISTPSAQAAYNATKDIPIIMTAVTDPVEAGLVKSLEKPGGNVSGTSDYL
                     SIDKTLELVKTLTPKAKKIGVIYNTSEVNSKIQVDSLHDYAKKNNYEVVEKGISSSSE
                     VNQAISSLVGKIDVLYVPTDNLIVSSMPIVSKVANENKIPIIASEEGSVSSGALACCG
                     IDYEKLGYKAGELAIEVLEGKSVGDIPVTTLDETEIIINEDTLKALDMQKLSADNIKY
                     IKSDENAKSAK"
BASE COUNT         1241 a          419 c          485 g         1087 t
ORIGIN      
        1 gccttagctt ttgtattcat ctgtaaagtc cttttagatt tattcctaaa aacaggtctt
       61 ggatacactt taaaaggtgt tggtgataac tctcaaatga ttaaatccct aggtataaat
      121 atcggttcta taaaaatact aggacttatg atttcaaatg gacttatagc tttatctggt
      181 agtcttatgg ctcaattctt gggattctca gatgtaaata tgggtatagg aactttagtt
      241 cttggaattg cctctatcat aattggtatt acattattta agaaatttac ttttatcaaa
      301 gatactactg caataattgt tggctctttt atataccaat tcactatata ctttgcaatg
      361 agtttaggaa tgttatcaac tgacttaaaa ctaataactg ccatagttat aatagctttc
      421 ctagctactg gtaacttaaa tatttcacta aaaaaaaaca aatacaaagc tagtaccaaa
      481 aataaatcag aaaaaagagg tgttgtagat gttacaaatt aaaaatcttt caaagagttt
      541 ccctaatcca tatggtgaac ctaatactat ctttgaaaat ttatcaatcg atatagaaga
      601 tggtgaattt gtaagtatca taggtagtaa tggaactggt aaatctactt tattaaatat
      661 aatatctggg cttataaaag aatcttctgg tcaaattact ttagatagta ctactataac
      721 aaatttagct gagtataaaa gaactcaaat agtaagtaga gtttttcaag acccaagcct
      781 tggaacttgt ccttctatga cggttagaga aaatttatct ctagcactta ataaagggaa
      841 attattgaac ttaaaaaaat gtcttcgtca taaaacgaat gacttggaac acttacttga
      901 aggaatttct ttggatttaa aaaaatattt agatattaaa gtacaatatc tttcaggagg
      961 tcaaagacaa tcactatcac taattatgtc tagcttagca agtcctaagg tcttattact
     1021 agacgaacat acagcagcac ttgacccaaa aacatcaaat gaagtaatag agttaacaga
     1081 taaaatcgta agagagaaaa atataactac acttatggtt actcacaact tgaaacacgc
     1141 tcttcaatat ggagataggt tgataatgct tcataagggt gaagttgtat tagatgtaaa
     1201 agataaagaa aaagaagatt taacagttga agaaatctta gaaaaatttg aatatgcagt
     1261 ataagaaatt aaaatcttag ttttaatcag aaatatttat aatctatcat atgaatatat
     1321 gaacaaatat aattaataaa ttttaaggga ggaaaataaa atgataaaaa gtaaaaaaat
     1381 attaagttta attatagcag gagtacttgg tgtatcaatg cttactggat gttctcaaaa
     1441 tgatggctcc aatgcttcaa atgaaaataa agaaacagat agcaaaaaac aaaaaaatat
     1501 aggtattagt caattagtgg aacatccgtc tctggataaa gcaaagaaag gattcatcaa
     1561 agcactcgaa gataaaggct ataaagatgg agataatata aaaatagatt tccaaaatgc
     1621 acaaaatgat atgcctacta cacaaagtat tgctagtaag tttgtatccg acaaaaaaga
     1681 tttgatatat gctatatcta ctccatctgc acaagcagct tataatgcta ctaaagatat
     1741 tccgataata atgactgctg ttacagaccc tgtagaagct ggacttgtta aatctcttga
     1801 aaaaccaggt ggaaatgttt ctggtacatc tgattatctt tcaattgata aaacattaga
     1861 attggttaaa acattgactc caaaagcaaa gaaaataggg gttatataca atactagtga
     1921 agttaattca aaaatccaag ttgattctct acatgattat gctaagaaaa ataattatga
     1981 agtagttgaa aaaggaatca gctcttcaag tgaagttaac caagctattt ctagtttagt
     2041 tggcaaaata gatgttttat atgtccctac tgacaattta atagtttctt ctatgccaat
     2101 agtttctaaa gttgctaatg aaaacaagat tcctataata gcctctgaag aaggttctgt
     2161 atcttctggt gctttagctt gttgtggaat agattatgaa aaactaggtt ataaggctgg
     2221 agaacttgct attgaagtat tagaaggaaa atctgttggc gatataccag ttactacatt
     2281 agatgaaact gaaataataa ttaacgaaga tacactaaaa gcacttgaca tgcaaaagtt
     2341 atcagcagat aatataaagt atataaagtc agatgaaaat gcaaaatctg caaaataaaa
     2401 cttattaatt tcaaaaaata ggtaatatga agtaggtaat atgaaaactt tatataataa
     2461 gtactcttat ccaccctaac cctttgaaaa ttgtgcttat tgtagcaatt tgaatattgc
     2521 atataaagtt attcattttc cataaaagtc gtctatattg acgactgatt atgaaagtta
     2581 tataactttc taatcactac ttgagctgtc caaaagaatt ttaatattct ccagacagct
     2641 tttttttatg atatttgatt gatatacatg tctagttatt ccatatttag taaatatttt
     2701 gataaaattt ccacattcac ttataactta ggataacgtt ttttgcaaac aatacattaa
     2761 tttaaaagta ttctgagtat acattattta gtattttaat taaatttagc agttgacttt
     2821 tattattgta taatttataa tttataacaa gtcgagaata catataattt tctgactaat
     2881 taaaatatta aaagggagag ataattatga atactttatt aaacaataga aaatattatt
     2941 attattatag ccactatttt tagggtttgt acctacgttt taacatagat acagacccct
     3001 taagactact aaaattttgg gattgtatct atgttggcta tattgtttat aaagttttca
     3061 tttaactata taagagccac atagattaaa ctatgtggct tattcgtgtt tttaccacat
     3121 agttttgtac actatgtggt ttttttatac acaaaattag caaataatta aaattataaa
     3181 aatattttca aaggagtgtt ttatttatgt caggtattat atctgtaatg ac
//
LOCUS       DAEQAF010000180         3221 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.184, whole genome shotgun sequence.
ACCESSION   DAEQAF010000180 DAEQAF010000000
VERSION     DAEQAF010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3221
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.184"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            322..2457
                     /gene="rnr"
                     /locus_tag="KRN00_003564"
     CDS             322..2457
                     /gene="rnr"
                     /locus_tag="KRN00_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBH1829381.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
BASE COUNT         1423 a          287 c          574 g          937 t
ORIGIN      
        1 atacttatat gagatgaata ttttaccaat cctatttgat ggtgtataat taggtgataa
       61 agagtaattt aagcaattat gataaagaat aacttaagta attataatga tatttacaaa
      121 taatttataa aacatcataa tttgtttgaa gttagtatga caaagcttac attaaatcaa
      181 aaatataaat aagtaatttt aacttgtaat aataataagg aaatatagaa aattatgtga
      241 taagtaaaaa atgttttgtc tgaagaaata taaaagacaa tataaataat aatataatga
      301 aaagtaaaac aggagggaaa aatgatacca ggacttaaag aaagtttgct aggattaata
      361 aatgaaagtg catataatcc tctaaaaaaa gaagaattag cagaaatatt tgatatacat
      421 tcatcagaaa tgccaatgtt ttataatttt ttaaatgaat tagaagaaga tggttatatc
      481 tgctttacta aaaaaggaaa aatagtatct cccaatcaaa tgggatactt tgttggaaaa
      541 tttgtatcac acaaaaaggg ttttggattt gtagaatctg atgttgaata tacacaggat
      601 ttatttatct caagtgacaa tataaatggt gctatgcata atgatagagt tatggcagaa
      661 atagtagtac ctgcaactga agaaaagaga gcagaaggaa gaatagtaaa agtaataaag
      721 agagaaataa ctagaatagt aggtactttc caatcaagta aaacttttgg atttgtaaca
      781 ccagacaaca agaaatttac taaagatata tatataccta aaaaacattt tagtggagca
      841 gtagataatg ataaggtagt atgtgaaatt acagtatggc cacaagagga tagaaaacca
      901 gaaggcaaaa ttatagagat actaggtcaa aaaggtgaaa gaggcgtaga aatagattct
      961 ataataagag aacatggtct tccagaagaa tttccaaaga aagtattgca agaagcagaa
     1021 gctgtagctg ttgagattcc tcaagaagag ataaaaagaa gaagagattt aagagattta
     1081 aacatattta ctatagatgg agatgacgca aaagacttag atgatgccat atcaatagaa
     1141 gtattaccta atggaaactt caaactagga gttcacatag ctgatgttac acattatgta
     1201 agagagaaaa ataaacttga caaggaagcc ttaaaaagag ctacatcagt ttatttagta
     1261 gataaagtaa ttccaatgtt gccaaaaact ctttcaaatg gagtatgtag cttaaatcca
     1321 tttgaagata agttaactct ttctatattt atggaaatag accataaagg aaatgtggtt
     1381 aaacatgaaa tatgtgaatc tgtaataaat tcaaaagcta gaatgactta tacagaagta
     1441 tctgatatat tagaaaagga tgatgaaaaa cttaaaaaga cttttgaaca tgttgttgaa
     1501 gattttaaaa atgctgaaat tttagctagg attcttatgt caagaaggga aaaaagagga
     1561 gctatagact tcaatttccc agaggcaaag ataattctaa atggaaaagg cgaagttgta
     1621 gatataaagc catatgaaag aagaatatct aataagataa tagaagaatt tatgcttata
     1681 agtaatgaga caattgccga acatttttac tggatgggaa taccgtttgt gtatagaata
     1741 catgagacac catctttgga aaaaatggaa gaattgagta agtttatatc tacatttgga
     1801 tatataataa aaggtgataa agaggaagta catccaaaag cattacaagg tataatagag
     1861 aaaataaagg gcaaaaaaga agaaggagct atcagtacta taatgcttcg ttctttaaaa
     1921 caagctaagt actcaccaga atgtagtgga cattttggat tagcagctaa attttactgt
     1981 cactttactt caccaataag aagatatcct gaccttcaaa ttcatagaat aataaaagaa
     2041 tctttaaata ataaaataag tggaaaaaga caagaacagc ttactactat agtggattat
     2101 gcatctgttc aatcatccga gaaagaaaga aaggcagagt tagctgaaag agatgtacat
     2161 gatttctata aggctcttta tatgaaggat aaagttggtc aagaatttga gggtgttgta
     2221 tctagcgtga cttcatttgg aatatttgtt gagttagata ataccataga aggattgata
     2281 agacttgcaa atatgaatga tgattactat atttatgatg agagttctta tagtgtttta
     2341 ggagaaagaa ctaagaagtc atataagata ggagaccttg ttaagataaa ggttgaaagt
     2401 gttaatgtag attttaaaga aattgacttt gagatagttg aaaaaataga ggagtagata
     2461 aaacagctaa aataagagat aacaagttgt agtatttatg atatgtataa atatatagtg
     2521 cacaatactc tataaaataa atgataaaaa taggtaattg agaaatatct aatggaaata
     2581 gttaactgaa agataaataa ttaagaaata tttaatgaaa gtagctaatt gaaaaataag
     2641 taattgagaa atgtttaata gaaagagcta actgaaagat aagtaattaa gaaacattta
     2701 atagaaaaag ccaactgaaa aataaataat taagaaatgt ttaatagaag tggctaattg
     2761 aaaaataagt aattaagaaa tgcttaatag aagtggctaa ttgaaaaata agtaattaag
     2821 aaatgcttaa tagaagtggc taattgaaaa ataagtaatt gagaaatgct taatagaagt
     2881 ggctaattga aaaataagta attaagaaat gcttaataga agtggctaat tgaaaaataa
     2941 ataattaaga aatgtttaat agaagtgact aattgaaaaa taagtaatta agaaatgctt
     3001 aatagaagtg gctaattgaa aaataagtaa ttgagaaaca tttaatagaa aaagctagct
     3061 gaaagataag taattaagaa atatttaatg taaacagata gtttaaaaat acctaattaa
     3121 gaatagatat taaaaaatat aatttcaata taaaaataag tgtatcattt aaaatttaag
     3181 atacacttat tttttattta agataacttt tcttttttag a
//
LOCUS       DAEQAF010000181         3201 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.185, whole genome shotgun sequence.
ACCESSION   DAEQAF010000181 DAEQAF010000000
VERSION     DAEQAF010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3201
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.185"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            228..1670
                     /locus_tag="KRN00_003565"
     CDS             228..1670
                     /locus_tag="KRN00_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBH1829382.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            1712..2065
                     /locus_tag="KRN00_003566"
     CDS             1712..2065
                     /locus_tag="KRN00_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829383.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            2256..3077
                     /locus_tag="KRN00_003567"
     CDS             2256..3077
                     /locus_tag="KRN00_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBH1829384.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
BASE COUNT         1244 a          327 c          557 g         1073 t
ORIGIN      
        1 attacaaatt gttactaaat ataggtacat tagaacaaaa atctagtaaa ttgtaactaa
       61 aatgtaaatt tttcctttaa tctatacaat attatggaaa ctttttgtaa tttatgatat
      121 aataacaaat atataattat taaattataa taaatgacta tagcgtagat gtaatactat
      181 gttatagtca tttttgaatt aaacttgata tatcaagggg gaagaatatg agaacaatta
      241 gaagagtttt agcattaggt ttaacattag ctatatttct aataaatgta cctaatgtag
      301 atgcattaac atcagataca attaaaggta acaatatata tgagacggct ggattaatag
      361 cagataaaaa gagttatgat acagcaatta tggtaaatat ggataattct atagcagatg
      421 gtctttcagc aagtggtctt gcaggtgctg ttgatgctcc aattttgctt gcacaaaaaa
      481 ataagatacc aaatgaaaca aaacaaagat taaaaaatgt taaaaagata tacataatag
      541 gtaaagaatt atcaataagt aaatcagtag aaactgaact aaaaaacaca ggggcacagg
      601 taactagatt gggtggagat gacagaataa agactagtta tagtgttgct aaagaggtaa
      661 atggtatcaa aaaagttgat gaagtgatat taactaatgc atataaagga gaagcagata
      721 caataagtgc tgcacctgta tcagtaagag atatagctcc tatagtactt acagatggaa
      781 agagtgtgcc tttttcaaca agcaatgtaa aaacatatgc agtaggtggg agtatatcaa
      841 tgagcactag tttagttaat aaaactaatg ctaaaagact tggtggttca gatagatatg
      901 atacaaataa gaaagttata aaagagtttt atccagatgc atcagaattt tatttgagtg
      961 atggatatga tttagtaaat gcacttacag gttctacaat tgctaaggaa aatccaattg
     1021 tattggtgtc agaaagtagt gataagtcta tattagcagg agcagataag attactagat
     1081 taggttcaat aagtgacagt gtgtataata agtgtgtttc tgctgcacaa aataatggcg
     1141 attcgtctac aaaaggtgag tcacctatga aaaatgagac aagcatatta ggtcagccaa
     1201 cagctagttt agaagcgtgc ttaaaatggg caaaatctaa aaaagctaat gatttattta
     1261 tagagttaat accaatatta tatgatactg ctgttcagga aggtgttaat cctgttttgg
     1321 cagtagctca atctgcaaaa gaaactggtt tttgtaattt tggtggagta ttagatgcat
     1381 catttaagaa tccttgtgga cttaaaactt ctgtaggtgg ttctgatact gataagaatg
     1441 cccattcaag atttgatact tgggaagaag gaatattagc tcaaattcaa catttatgct
     1501 tatatgcagg acaagatggt tacccacttt caaatccagt agaccctaga catgaaaaat
     1561 ctttatttgg taaggctaaa acagttgaaa gtttatctaa taattgggct ggaggtcaat
     1621 atggacaaga tttagtaaga atgatgggag aaattgaggc aacaaaataa ttgaagatta
     1681 tcaaatatcc aataaataag gattgattat tatgaaaaag agtaatattt ttagtatcat
     1741 atttcctaca gtcataatgg tgctaatgtt tttaactttt gctacagata tatttaatat
     1801 tccagatatt caatctaaaa gtatttttgt tgtgggaatg gttttgattt ttccaatttc
     1861 ttttttgata caagggataa tttgtgtatt aaataagact aattggattt tatctcttat
     1921 tgtgtcttta gtaacttata tagtattaat gtatatattt ttaaatgatt ctgcatatat
     1981 atatgtttta ctttatacag ctttttatat gattggacat ataacagcta aactctatta
     2041 caaaattaag acttttaaaa attaaattga agtatataaa agtaacatta agagaagtat
     2101 ccttaatgat tttctaaaat cagaaatagg tgcttctctt ttttgtaaaa ataaaagtat
     2161 gtaaataaaa tttaaccatt ataattttct tttaacaaat gtatacaata aacttgttgt
     2221 ataattaaga tagataaaat aaagggaggg ataatatgaa tttaatagat aatcatattc
     2281 atactaattt ttcaagtgat ggaaaggatt ccatggaaga tacaataaaa aaagctataa
     2341 gtattggtgt tagatatttg acttttacag accatttaga acatgatgaa gatagaggat
     2401 tttgcataaa ttataatgac tatgttccag tatttaataa gtttaaagaa aaatataaaa
     2461 aggacataga gttattacta ggtgttgaag tgggttacag aaaacatcta aaaaatgaaa
     2521 tagaagaaat aataaattct aatccttttg attttgtatt gtgctcaact catacaattg
     2581 acaatgtacc tgttccatca aaggcgtatt ttaaaggtct tagcaaagaa gatgcgtatt
     2641 ataaatattt taatagcata cttgaaacta atcgtgaatt tggagattac aatatatatg
     2701 gtcatttgga ttatatatct aggtatggaa tatattcaga taatagagtt atatacaatg
     2761 actttaaaga tgttattgat gaggtcttaa agtcaataat caataatggg agtggtatag
     2821 agctaaatac ttctggttat agatatggac taaatgctat acatccaaat gaagatattc
     2881 taaaaagata taaagaactt ggaggattta tagttactgt aggttctgat tctcataggg
     2941 tagaagatat atgcaaagat tttgatgtgg cctatgatat gcttaagtat cttgacttta
     3001 aatatgtatc tttatttaaa gaaagagaaa cttattttgt aaatatagaa aaagttaaat
     3061 ctaacaatat agcttagagt gtgttttgaa gtaaattaat ggatagttaa aaagttaata
     3121 gttataatat tgtatcctct agaaaaatac tagaggtttt tattttgcta aaataactaa
     3181 atagaattaa atttaaatag t
//
LOCUS       DAEQAF010000182         3181 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.186, whole genome shotgun sequence.
ACCESSION   DAEQAF010000182 DAEQAF010000000
VERSION     DAEQAF010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3181
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.186"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(205..381)
                     /locus_tag="KRN00_003568"
     CDS             complement(205..381)
                     /locus_tag="KRN00_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829385.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(435..531)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            1327..1728
                     /locus_tag="KRN00_003569"
     CDS             1327..1728
                     /locus_tag="KRN00_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBH1829386.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLISIALKPLAQPPFPLERIIEKLEKEETE"
     gene            1725..2792
                     /gene="rsgA"
                     /locus_tag="KRN00_003570"
     CDS             1725..2792
                     /gene="rsgA"
                     /locus_tag="KRN00_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBH1829387.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQVV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVYRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LMGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWEAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
BASE COUNT         1142 a          389 c          530 g         1120 t
ORIGIN      
        1 ttttaagaga tgtttatttt cacatagata agagaattta agttctcata tttattattt
       61 gatacaaatt tacatcttta ttatatgtat tttaaataaa aaataaaatt atgaatacta
      121 gaaatctatc ttaattagct ttctaacata aggctattta aagtagataa aactaaaaag
      181 ggttctctag aaaaccaaat ctatttaatt atacttactt actaatacca tcacttgatg
      241 caaacaagat tctaccacat tttctccgta ctctagtata aaatcatcta gttgtgtatc
      301 tataaaatca caataatcat atgaactacc aatataagca gtcaacatat gtgtacatct
      361 atccatttta tctctaaaca tatatattat tatcccccta aaaaactttc ataaaaacaa
      421 aaagaatatc tctttttggc aactggctga cataactcat agtttatttt ataagcgtta
      481 gtccctatag ctttgcgtca ctaaatttct ctagttttgc cgatttagtt ttattctaca
      541 attacaataa tacaatagaa ttgcttatta ttcaatatac ttatttgaaa attaaataaa
      601 tttacaaata tgaatgttat tttatatcaa aaaaatagac tatgcatgta gaatatatgg
      661 aaaaacttga ttgtaggttt tgtatgaaaa gacagttgtt attaatttaa gtgagataaa
      721 ttgagcaata ggcataaaat gagaaaacaa ataatagcag ttaattttta ttattaatac
      781 taggtgaaca ttaaatttta aaataccact agattttata gaataagaaa atgagacaaa
      841 cataaatata tgaatatatt aaattatact tgaacatact tatattttat gataaaattt
      901 caataataat tattagtgaa ggagtgtctt gcctgatgtc agagttatat ataatggtaa
      961 ccaacaaata aatagttgga gacgcatatg ggttctgttt aatcagaatt tttaagtgta
     1021 tttttgatac atttgattgt tgtgtcttac tctgccttta tagataacta acattagaca
     1081 acaaataata atattacata ttactttgtt aaattatggt gtagtgggct ttaatctgct
     1141 acacttttat taattttaca cagtattatt ttgaatataa ttatgttgaa atagaagata
     1201 ctaaattttc tagtccacag gggttttctg tttttgtgta ggtaaatatg tataccacat
     1261 aaaaaggcag atataaatac ctgtggactt tttttgtaga aaatacacga tacggaggaa
     1321 ataaaaatga attataaaaa tagaaaacga gcttattatc aggaaaattc ctgtatggat
     1381 aactttattt gcaaaaattg tggttgcctt gtagttcctg aaggagctgg tacacaacat
     1441 agaaatcatt gtccacattg tttacatagt cttcatgtag atatcattcc tggtgaccgt
     1501 gctgcagatt gtgatgctaa tatggaacct attggagtgt gggtgagaaa aaatggtgag
     1561 tgggcaatta ttcatcgttg tacacgctgt ggacatctta gttctaatcg tattgcagct
     1621 gatgataatt cagtgaaatt aatatcaatt gcattaaaac cactggcaca gccccctttc
     1681 ccactagaaa gaatcattga aaagttggaa aaggaggaaa cagaatgaat ggtatgaaac
     1741 aaataaattt acaagactat ggtctaaata ggaattttat tactcaaagt atggaatatc
     1801 atgatttata ccttgctcgg attatctcgc aggaaaagaa cttttatcaa gttgtatgtg
     1861 taaatggtgt actgtttgca gaagtttcag gaaaactgcg ttttgaggct actatacaat
     1921 ctgattttcc cacagttggt gatttcgtta tgttggatcg ttgcaataat aaaaatggta
     1981 atgctattat tcatcatgtg cttcatagaa aaagcttgtt tgtgcgtaag gctgctggaa
     2041 aggtaaatga ggaacaggtg gttgcagcta atattgacat tgtttttttg tgcatgtcac
     2101 tgaataagga ttttaacatt catagattgg agaggtatct gtctttaaca tgggaaagtg
     2161 gagctatccc agtagtagta cttactaaat cagacttatg tgacaatgtg tatcgtaaat
     2221 tacaagtagt taattctata gccttgggtg tagatgtagt tgttacctca tctatagagc
     2281 cagatggtta taaacagatt tctaagtata ttaaaccagg ctgtactgtt gccttacttg
     2341 gttcttcagg agttggaaaa tcttcattaa ttaattgtct gatgggtgga gaatttttaa
     2401 atacaaagga aattcgcata gatgatgata aaggaagaca tgccacgact agacgagagc
     2461 tatttttaat ttcaggtggt ggtattgtta ttgacacacc aggtatgaga gagttgggaa
     2521 tgtgggatgt ttcagaaggt ttagataaaa gttttgcaga tatagaagct tatttcggaa
     2581 aatgtcattt tcgtaattgt actcacacct cagaaccagg ctgtgctatc tgggaagcta
     2641 ttgctcatca agaactttcg cctaaaagat gggaatccta tcgtaggctt aaaactgaag
     2701 cagtatttgc agacaataaa agcgaatact tagcaaaaaa agaaaaaaaa tttaaaaata
     2761 tctcaaaaat aaataagaag attagaagat aagtgtagtt tttttgttca ttctatgagt
     2821 ctatatacta ttaatatatt aaatttgcca tcaatttgtt actttaatgt gattttgatg
     2881 gcaaatttgg tttgtggtat tatttaaagc aatttattaa tttttttaat aaagtttgat
     2941 tttttatatg atgatatata catgtgataa tgtatacata tttgttacga taggctcctt
     3001 tataaagagg tcttatgtaa gataagaaaa ggcatattta tactaataca taatagagta
     3061 tatgcttatg tatgatagag atgtttctta agagcaaaac tgcaatattg ctaatttata
     3121 aagtaaaaat atatgaatta taaaatacaa ataatatatt tataaaaatt attgttttaa
     3181 t
//
LOCUS       DAEQAF010000183         2987 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.187, whole genome shotgun sequence.
ACCESSION   DAEQAF010000183 DAEQAF010000000
VERSION     DAEQAF010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2987
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.187"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            104..610
                     /locus_tag="KRN00_003571"
     CDS             104..610
                     /locus_tag="KRN00_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBH1829388.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            738..1754
                     /locus_tag="KRN00_003572"
     CDS             738..1754
                     /locus_tag="KRN00_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBH1829389.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            2108..2812
                     /locus_tag="KRN00_003573"
     CDS             2108..2812
                     /locus_tag="KRN00_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBH1829390.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     GGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
BASE COUNT         1261 a          281 c          528 g          917 t
ORIGIN      
        1 taatttgtaa aatcttccta tatcatataa aattaagtat tgattagtct attacataaa
       61 tatagaatat aaatatatcc atttaataat aaggagaaga gatatgaaag agtatgtagt
      121 tgtggattta gaaactacag gattagatcc atataaaggt tgtgaaataa tagaaatagg
      181 aataacagaa ataaaaaatg aacaaattgt aaaaaactat tcaaggttga taaaacctaa
      241 ggggataatt tcttcattta taacagaatt gacacatata agtaatgaaa tggtagaaaa
      301 tgaagaacca ctagaattag ttttacctag atttagaaaa tacataggtg atagaactat
      361 aattgcacac aatgcgaaat ttgatttaaa atttttaaat tactatctta gaatgttaga
      421 tttagaacca ataaacaatt atatatgtac agtagagtta ttaaaaaaat gtaaaagtta
      481 taaaggaaaa aacaagaaac ttgaaacagc ttgtgcttat tacaacatag agaatataaa
      541 tgctcataga gctgacagtg atacattagc aactgcaaaa ctatttttga aaataaaaga
      601 tgaatattaa ttataaatat agagaaaatt agtgaaaata tcctttataa aattgaccct
      661 taagcttaca attttgttct ttgatttatt ttgtagaaca atgtataatg taccttatat
      721 gaagaaggga gactaaaatg ggttattaca atgataatga taataataaa ataagacgta
      781 aaaaaattag taacaacaaa gatagtaata aaaaatctaa acattcttat acttcggcaa
      841 ataaaaaaaa taaaagtcct aatacaagtt ccagtaaaag aatgagtgaa aaagtagatt
      901 cacagaatct tataaaaaga gatagagata gttttacaag agataatgta agacctttaa
      961 atacagatta caatcaaaga gaaagaagaa gagtcgagta taaacaaaga gagaaaaaat
     1021 taaaaagtaa aaaaagaaaa aaacaaaaaa ggattagaat agttagagca ttattatcta
     1081 ttatgttagt tgcactaatt atattttcag tggcaggtgc aatatttaca gtttcagcta
     1141 taaaagggtc accagaagtt actaaaaagt taattaggtc taaatatata agtagtgagg
     1201 ttgtaagtat aaaacaaatg ccaaatgatt taaaacatgc aatagtttcc atagaagatg
     1261 agagatttta taagcataaa ggagtagatg ttatttctct agttaggtca gtattaaaca
     1321 atgtgtttac agatacaaca caaggtgcaa gtactataga tatgcaagtt tcaaaaaacc
     1381 tgcttactag taatgataaa actatgaagc ggaaaataag ggatatgtat aatgctaagc
     1441 agatgaataa gattatgact aaggatgaaa ttcttgaagc atatttaaat aatatgtatc
     1501 taggtaaaaa tgcatatgga gctgcaaagg gagctgaagt ctactttggt aaaaaggtta
     1561 gtgaattaaa tttagctgag tgtgctatgt tagctggtat gacaaataat cctgcaaggt
     1621 atattgacca tggagaggct aagaagagac aagtgattgt actgtataag atgcatcagc
     1681 ttggttatat aactgataag gagtatagaa tagcaaaagc tgatgacact ccatttaaat
     1741 cagaaattga ttaaaattgt aagaatatag tattttcaat agtttaaaca aacgaaaatg
     1801 taataaaaaa ggtgatttgc cacccatttg ccaccataat tacaatctaa tggcaaattg
     1861 ttttaatgta caaactagat aatagaatat tgttttaaat gctatattat gctaaaattt
     1921 aattgtattt tgtaaattaa aaaacttata atttagtttt ctagggttcc gcattttgta
     1981 atggtcaggt ccaagagaaa acgcacaatt tttgtgtaca cggaaggata aaagcctggg
     2041 agatatttaa gaatatttct ataggctttt ttatttttac atattttaaa tttgaggagg
     2101 ttttctaatg aaaaaatttg ttattgagga tgcattttgg aatctatttc ctagtgcaaa
     2161 aattggagtt gttatttgta atgatataga taactctata aaagatgaag actataagaa
     2221 aataattttg aagggagaag aagaagcatt aaaatacttg gaggactcag aatttagcaa
     2281 caaccaagtg attaaagtat ggagagaagc atttaaaaaa tttaaaacga aaaaaggagc
     2341 aaggtcttct attgaagcat tattaaaaag agttcataat ggaaataata taggaactat
     2401 taacccttta gtggatatct acaattttat ctcattaaaa tatgcattac cttgtggagg
     2461 ggaggatata gataaattta taggagatat taggctaact agagcaattg gtaatgagga
     2521 gtttatccca ctagggacag atgaaaattc atttccatat gaaggagaaa taatttataa
     2581 agatgatggt ggagcaattt gtagatgttg gaattggcgt gaagcagtga gaacaatgct
     2641 tactgaagat actaacaatg cctttttatg cattgaatta gtagatgaaa gtagatttaa
     2701 agaatttgaa aatgctttaa atgaattagc taaaatagtt caagaaaaat tgggtgggaa
     2761 ttgtaaaatt tcaattttag atattgataa taaagaggta tcagtggatt aatatggagg
     2821 tgctgttgta atggactatt ctagttataa agatacttat atttagggta agaaggtcta
     2881 ttttagatgt aacgattatc aaaggatata atatagaaaa taaaaatgta gaatataaaa
     2941 agcctttaaa ataagaaaaa aatgtatttt aaaggctttt attatac
//
LOCUS       DAEQAF010000184         2922 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.188, whole genome shotgun sequence.
ACCESSION   DAEQAF010000184 DAEQAF010000000
VERSION     DAEQAF010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2922)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2922)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2922
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.188"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            68..141
                     /locus_tag="KRN00_003574"
     tRNA            68..141
                     /locus_tag="KRN00_003574"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:100..102,aa:Gly,seq:tcc)
     gene            156..272
                     /gene="rrf"
                     /locus_tag="KRN00_003575"
     rRNA            156..272
                     /gene="rrf"
                     /locus_tag="KRN00_003575"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            546..2564
                     /locus_tag="KRN00_003576"
     CDS             546..2564
                     /locus_tag="KRN00_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1829391.1"
                     /translation="MRRNTKLLTTGILSMAIVTPTIAFATESNAMENNADLNINLEKK
                     SIVLGSTSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKNLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKENLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPTKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
BASE COUNT         1174 a          362 c          498 g          888 t
ORIGIN      
        1 gatatatatg tagtttttag ggtgctaact ctaaaaaatt agttttacta atttataaaa
       61 atttaatgcg ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt
      121 cgatcccctt cacccgctcc aaatccaaaa gattatgtgg ttacaatagc agagaggata
      181 cacctgttcc cattccgaac acagaagtta agctctctag cgctgatggt acttggtggg
      241 aaactgcctg ggagagtagg acgtagccac gtaatctttt tttgttgtat taaatttaat
      301 aaacctacaa ttgttatatg tttttatttg tcttttatag atttttttgg caataaatga
      361 tatagtgaag ataattaaat atattcaata tatttaattt ttttattttt tgtttttata
      421 atttttttag aagtttattt tttatataat tatttataat tttgggtaaa aacactttga
      481 tatattttca aaagataaaa gatcaaaaaa caaggtagaa atttatgtta agtaaggaga
      541 ttaatatgag aagaaataca aaattattaa caacaggaat tctttcaatg gcaatcgtca
      601 cacctacaat agcatttgct actgaatcta atgctatgga aaataacgct gatttaaata
      661 taaacttaga gaaaaaaagt atcgttttag gtagtacctc aaaagtcagt gttaagttta
      721 aagaaaaacc agatgcagat agcattacat taaagtataa atgctatgat atgccattgg
      781 atacaacttt aaactacaat caatcaactg agtcatatga aggaactatc aattataata
      841 aagacccaga atatctaaat gtttgggaac tacaagggat aacaataaac agcaaaaata
      901 atcctaaaaa tttaaacaaa caagaactag aaaagatggg attaaattta aaagactata
      961 atgtaacgca ggaatgtata attgaagata taacttctag aaaagatgta aataaatatt
     1021 taagaaaaac ttctgcacct attacagaac ttacaggaag tgatagatac gaaacagcag
     1081 ttaaaataag taaagaaggc tggaaaaatg gttcagataa ggtagttata ataaatgggg
     1141 atgtaagtat agatggcatt atatcaactc cactagcaac tacatataat gcgccaatac
     1201 ttttggttga aaaaaacaat gtacctaata gtgtaaaatc agaattaaag cgtttaaatc
     1261 ctagggatgt aattataatt ggagatgaga atgctatttc taaaactact gctaatcaaa
     1321 ttaaatcgac tgtaaatgct agtcaaacac gtctaaaggg ctctaataga tatgagacat
     1381 ctttattgat agcaaaggaa atagataaaa atcatgatgt ggaaaaagta tacataacaa
     1441 atgctaatgg cggagaagtg gatgcactta ctatagcagc aaaagcaggt caagacaagc
     1501 aaccaattat attaactgat aaaaatagta ttacagacaa cacatataaa tggttaaaga
     1561 gtgaggattt acaaaatgct tattttatag gtggccctca aatgatatca acaaatgtta
     1621 taaataaggt aaatgatata actaaagata atgttactaa taatagagta tatggagcag
     1681 atagacacga aacaaatgca aacgtaataa aaaaattcta tacagatgat gagctagagg
     1741 ctgttttagt agctaaatca gatgtacttg ttgatgcttt agcagcaggt ccattggctg
     1801 ccaacttaaa atctccaata cttataacac caaagacgta tgtatctgca taccataaag
     1861 aaaacttaga agctaaatcg gccaataagg tatataaaat aggaggagga ttgacttcta
     1921 aggtaatgaa ctctatagca tcatcattat ctaaacacaa tacaactcca acagaaccag
     1981 gaaatagtgg gggtaagaca gttatgattg acccaggaca tggtggttcg gacactggaa
     2041 caacaggtaa accattaggg ggtattaaag aaaaagacta tacattaaat acttcacttg
     2101 cgacaactga atatttacgt tcaaagggat tcaatgtaat aatgacaaga gatacagata
     2161 agactttatc tcttggaaat agaactgctt tatctaactc tttgagacca gatttattta
     2221 cgagcataca ctataatgca tctgatacaa ctgggaatgg tgtagaagta ttttataagc
     2281 ttaaagataa agatggagga actactaaga ctgtagctac aaatatatta aatagaattt
     2341 tagagaaatt taatctaaaa aatagaggtg caaaaacaag aacactatca actgacccta
     2401 caaaagatta tttatatgtt ttaagaaata atgatatgcc agctgtactt gtagaatgtg
     2461 catttttgga taatgagaaa gatatgagtt tacttaatac atcaaataaa gtaaaagaaa
     2521 tgggtacaca aataggtaaa ggcatagaag attcattaaa atagtctaca atgagagcat
     2581 agaaaaattt aaaataaatt aatctgcaat tttaaattta gactaaagct ataagataag
     2641 aatgtaatta taatagtaat aaagactgta tatacattgt gcatataagt gcgaaatgag
     2701 gtatatacag tctttttatg attaattgta aaaggattta tattatatga agaatttaca
     2761 tatcttaagg ctacagttaa ttgtcaagag ttggagtatt catttgtaat acacaataaa
     2821 agcttaatta ctatatttta ttgtgtgttt gtgtgttttt tgtggatttt tatgtcaata
     2881 aatgatatag tatagataat taaatgtatt aaatatattt aa
//
LOCUS       DAEQAF010000185         2875 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.189, whole genome shotgun sequence.
ACCESSION   DAEQAF010000185 DAEQAF010000000
VERSION     DAEQAF010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2875
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.189"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            337..2148
                     /locus_tag="KRN00_003577"
     CDS             337..2148
                     /locus_tag="KRN00_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBH1829392.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVAAALSKTFNIKETCARIGSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSMMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
     gene            complement(2236..2817)
                     /locus_tag="KRN00_003578"
     CDS             complement(2236..2817)
                     /locus_tag="KRN00_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829393.1"
                     /translation="MLYLLKINQFEKSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
BASE COUNT         1075 a          303 c          408 g         1089 t
ORIGIN      
        1 aatatagatt atgtatatgc caaatttaaa aagagacata aagacattat acaaatatat
       61 tattggggtg atattttgta agaaaagaag tgatgcagta aattaattga gtaatttaaa
      121 aatgatttaa tgataatgtt gatgaatgtt taaaaagaaa ttttagaaaa acgtatattg
      181 ctgtttgtgt tggaggtgat gaatttgtag aatttatagg gtataaatga ttaaactatt
      241 taagataaat acatatcact gtaaaatatt gataatcatt ttttataaga gattgattat
      301 ttgcaaatta tatatattac aaatgaggta acaataatga agaaaaaata tgatttttta
      361 atttattctg ctatttggct agttattatt attcttttta tattttctct atatcacagt
      421 atagagcata ttaaaattat aagtcacact ggtactattc gcagtgaaac tcaaaaggtt
      481 gttaagcaag aattgaataa tgaaagaaat gatgacttga taaaacgact ggataatatt
      541 ctgataaagc taagaacagg taatggagaa aatggatttc aaagatgtga taataaagaa
      601 tttcaacaaa aactaaatca aatggattct atgtgggaat ctatgaagaa agaaattata
      661 aaagttagaa atggtgcttc aggtgataaa ttatataaat tgagtgaaga gtattctgtg
      721 ttgtctaatc aaattgtttt tatatctgaa aaacactcta atgcaaaatt gtattctttt
      781 gctactgcac tatttattta tcttatattc tcaacaataa gccttttaat ttgggaatat
      841 tataataaaa aaaggtttaa aagaatattt tatactgata atttaacaaa aataaaaaat
      901 caggttgcat ttgaaaacag agcgattgaa attttgcaca atgcatctaa caaagagtat
      961 gtactgctaa atattgatat tgacaatttt aaatatatta atgatacaca tggatatgaa
     1021 tatggagata aagttctaat aatagttgca gctgcacttt ctaaaacttt taatatcaaa
     1081 gaaacttgtg caagaattgg ttcagataac tttgtaatac ttgcaaaata tagagattct
     1141 cttttagagg atattcggga aatgctaact aatgctataa tctctgaatt agatatgaat
     1201 gtaactcaaa ctatatctta ttgtatagga gcgtacttag ttgaaattga taatttaggt
     1261 tataaatcca tcaattctat gatggataag gcaaatattg cacacaaggt aagtaaaaca
     1321 agaggaattt cctctacagt atggtataat gagaatctgt taaaacagtt acaaatggaa
     1381 aatagtattt ataattatat gtataaagcg atagaaaatg aagaatttca tatgtatttg
     1441 caacctaaat ttcaaatatc ttctttaaat gttgtgagcg cagaagctct tgtaagatgg
     1501 ttttctccag aacttggttt tttatcacca gatgaattta ttccattgtt tgaaaaaagt
     1561 ggatttatta ttgaattgga cttttatatg ttaaaaaaag cgtgttcatt tgtaaaaaaa
     1621 acgtttatga aaaaaaatca atatacatat ccgattgcag ttaatttttc aagggttact
     1681 atttaccaaa atagctttta tcaaaggttt ttagatactg ttaaagaata tgaaattcct
     1741 tttaagtata tagagataga ggtaactgaa agtgctttta atgaaatatc tcaaccagtt
     1801 atttcgattt tagaggagct taaaaagtta ggatttttaa tttcgatgga tgattttgga
     1861 tcaggatact cttcattaag tcttttatgt tctctatcta ttaatggatt gaagttagat
     1921 aaaagcttac ttaaagaaac atttaaccgg gagaaagtat atagtattat tcagtgtatt
     1981 attgaaatgt cacatcgtat aggcatgtct gttgtatgtg aaggtattga aactaaaaaa
     2041 gacttggaat ttttaaatac agttaaatgt gatgtaggac aagggtttta tttttctaaa
     2101 ccgatagaag aaaaagaatt ttttaacaaa tatgtaacta aaaaataata taattatttt
     2161 tatcagtcta tacattgagt cattttatat ctcgttaaat gactcaatgt actgttatgt
     2221 attttaaaat ataaattatt taaaacgttt tttatactta tatagaaatt cttctatatt
     2281 ttttgattgt tctcttattt caactgcttc tatatctagt aaataaagta tagaatcatt
     2341 tgtaagttca acatattcac catcttctga accgagtgca tgtctctcaa tttttaatcc
     2401 tttttcttca taatattttt ttgtttctat atataatgat tctcgctttt gtatgtagtc
     2461 tttcacttca ttatttggaa agttatatga atccactaat gtttcgccat ttataaaagt
     2521 tttctcggta gcaacttttt catcccaaca atggatttct tcccaagtaa aaaatatctc
     2581 agttccatct ggaatgaatg aaaacctggt aataatatat aaataattat tgaaatttac
     2641 ttcataatat tcaggaatat cttcaaattc catatagtaa tttgtataat taaaattact
     2701 attatctttt tttacaaagg gtattttttc aataaattta tatattgatt gttcattttt
     2761 aaaaattcct atatcataac ttttttcaaa ttgattaatt tttaataaat acaacattct
     2821 ttctcctttt attcaaaata taatttttat aaatttacta atctttagct ttttt
//
LOCUS       DAEQAF010000186         2872 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.190, whole genome shotgun sequence.
ACCESSION   DAEQAF010000186 DAEQAF010000000
VERSION     DAEQAF010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2872
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.190"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            50..1159
                     /locus_tag="KRN00_003579"
     CDS             50..1159
                     /locus_tag="KRN00_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBH1829394.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDLKNERMLSEIETAIESKISRRIIEL"
     gene            complement(1536..2720)
                     /locus_tag="KRN00_003580"
     CDS             complement(1536..2720)
                     /locus_tag="KRN00_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829395.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
BASE COUNT         1090 a          437 c          405 g          940 t
ORIGIN      
        1 attaattggt taataaaaaa gaaaattttt catgaaaggt aagataacaa tggatttcaa
       61 aagcttaggg attagtgaaa atacaataaa tattctaaaa aaatcaggaa taacaacacc
      121 tacacctata caaaaagaaa gtattaaact aataaaagaa ggaaaagatg taatagcaga
      181 agctcaaact ggaacaggaa aaacactagc ttttttactt ccgatatttg aaaatatatc
      241 attagatata aatgatatac aagtacttat actttctcct acaagagaac tcgctattca
      301 aataacagaa gaagctatga aacttaaaga atctaaagat gtaagtattc ttgcagcata
      361 tggaggaaaa gatattggtt ctcaaataaa gaaactaaaa ggaaatattc atatgattat
      421 agctacacca ggtaggcttt tagaccatct aaatagaaaa acaatagacc ttagtaagtt
      481 aaagactttt gttttagatg aagcagacca aatgttgctt atgggattta aaaatgaagt
      541 ggaagctatt ttaaaagaga cttcaaacaa aaagcaaaca ctatgctttt ctgcaactat
      601 aaattctcaa gtaaaaaaat tagcttatag atacacaaaa aatcctgttg tagtttctat
      661 tcaaaaagaa gaaatcactc ttaataatat aaaacaagaa gtagtagaaa ctacagatag
      721 aaaaaaatta gatgccttat gtaaggtact agatgaagat aatcctttta tggcaataat
      781 attttgtagg actaagagaa gggttgacaa tcttgaagaa gctcttgcta taagaggata
      841 taattgtcaa aaacttcata gtgatattgc tcaatcaaaa cgagaaagaa taatgaaatc
      901 atttagaaat ttagatatac aatacttaat agctacagat gtagcttctc gtgggcttga
      961 tatatctgga gtaagtcata tatataatta cgatttacca gaaacaccag aagactacat
     1021 ccaccgtatt ggtagaactg gtagagctgg tgaagaaggc tatacatgtg cttttattga
     1081 ccttaaaaat gaacgaatgt taagtgaaat agagacggct atagaatcta aaattagtag
     1141 aagaattata gaattataat ttatagattg cttaaaatac caatgtcaca caaacactgt
     1201 aatatataga aagctacaga aaacatgtat caatctatac tttgctgtta tactatttta
     1261 tattaaagaa aaaagaggct atccaaagta ggattagtct cttttattgt caaaataatg
     1321 aaaatatatt tgacttcata taaaaaagag tgccttataa actaaaagtc cattttgaga
     1381 caccctcttt ttatctttta ttcttagttt tatattgctt gtttatagtt gtttaatatt
     1441 agattttgca aataatctta ataaacatgc agatatatta tctatagtat tcttatctat
     1501 agtattctct ttagcaatat tttttgctac tacatctaat ttacattttc atttaattcc
     1561 gctggccatt tagcttctgg attttccttt gcaaacttct tattcttata atgtcctagt
     1621 gtaaggaatg gaattactat agtgaataga ccaagataac cacaatatcc atatccatat
     1681 ttaacaatat tacttaatcc tgtaagtgat ataagcattg acactaccat tattgcacaa
     1741 gctgtaaata cccttctttt cattcttgaa gaaaggaaag aaagtgcttt atggtcttca
     1801 aatctattta caagaccaaa tatagtagtt actcctgtag acattaaaca aaggaataat
     1861 gcaacattat aaattatgta tatagtatga tttccagatt gacctgcaac ataaagagta
     1921 gggagtgttg tttgcccagc agcaataatt tctctatacc atcccattag catagttaca
     1981 gcaagtccta atgcaattgc attcataaca aatgaaatta tcattgcctt agtagcttct
     2041 tttgagtttt taagaagtgg tcttgaacat cctgcaagtg taggtataac aaccgattga
     2101 aaacctgcat aaataaaagt attaagtatt ggcttgatat agccaggtgt gaaactcgtt
     2161 ctatttgata atatttcagt tatttctggt actttagctt ttataccaac aataaaaata
     2221 gtaagagtac atactagaat agctattgtc attgctgtag ctgctttaga tacaagcata
     2281 gcaccaaata tagtaaagac aagaagtaca actccaataa taaatacagc tacaaaataa
     2341 tttactccta tactttgaaa tactgctgct gcacctgcta taacagcact tacagctatt
     2401 aaaaccatta gatagtaata tatctcccat attatttcaa gttttggata tggtctccaa
     2461 agctcacaaa ataaatcctt ataattccta caattgttat tattatacat tatgataact
     2521 tctctcatgg tagcagtaag tataatcatt gctaaaattg ccataagcgg tgctgtccat
     2581 ccatactgca catagtactg agtttcttga ttccctgtag caaatcctcc tcctgcatgt
     2641 gaactaaaaa gaacgcttgc aacaccaaaa atagctaaca tagagcccgt tacttttgct
     2701 ttctttacac ttttttgcat gaaatcatcc tccctaaaat gatattgaaa gtttttattt
     2761 taacacttta ttgataaaac aataacattt ttgctcatta aattcaacta tatttttcca
     2821 atgactttac atttttaact tatttctacc tttgtattaa atatttttta ta
//
LOCUS       DAEQAF010000187         2842 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.191, whole genome shotgun sequence.
ACCESSION   DAEQAF010000187 DAEQAF010000000
VERSION     DAEQAF010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2842
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.191"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            50..2407
                     /locus_tag="KRN00_003581"
     CDS             50..2407
                     /locus_tag="KRN00_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBH1829396.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGIIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDDNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(2493..2810)
                     /locus_tag="KRN00_003582"
     CDS             complement(2493..2810)
                     /locus_tag="KRN00_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBH1829397.1"
                     /translation="MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
BASE COUNT         1057 a          327 c          473 g          985 t
ORIGIN      
        1 tatttgtaga tttgagtata aaaaagtgct aagttgaaag gagtaaaata tggataaggt
       61 taatttagaa aggtatagtt gtgatataaa tgttggttta aataaaaatc aacttcaaag
      121 tagaatagat gataatttaa ttaatgcatt tgataatgga aaaaccaaaa catataaaca
      181 aatttttaaa gacaatatat ttacactttt taatctcata aatattgttt tagtctgttt
      241 attagtttca gttggttctt ttaaaaatac cttatttata tttattgctg taattaatac
      301 tattatagga ataatacaag agataagagc taaaagatta ttggacaatc tatctgttat
      361 agtttcaaat aaggtatctg tcataagaga aaaagagaaa aaagagattg atgtacaaga
      421 attagtatta gatgatatta tgattttaaa aacaggtaat caaatttgtg cagattcaaa
      481 agttttaaat ggaaaattag aggtaaatga gtccttggtt acaggtgaat ctgatattat
      541 tataaaaaat aaaggcgatt ttttatattc tggaagtttt gtagtttctg gagaagcttt
      601 tgtaagagtt gaaaatatag gaaaagataa ctatgcaaat aagatagcta atgatgcaaa
      661 gatttctaaa aaacataatt ctcaacttag aaattcatta aatgcaatat taaaaattgt
      721 aggtataata ataattcctc taggaattat attgtttgca aaacaacatt ttggaaatgg
      781 agattctata gctacatctg tagtaggtac agtggcagct gtaaatggta tgataccaga
      841 gggattaaca ttacttacga gcattgctct agctgtagga actataaaac ttgctagtca
      901 taaaacttta gtgcaagaac tgtactgtgt agagactctt gctagagttg atacactatg
      961 tcttgataag acaggtacaa ttacagaagg taaaatgcaa gttgatgata tagtaatgtt
     1021 ggaagaagtg gatattaatg aaataatggg gaatatatgt aattctctca aagatgataa
     1081 tgcaacacta aatgcaataa gagataagta taatgtttta gatacgtata aagctaagaa
     1141 tttaatacca ttttcttcag aaagaaaata cagtggggtt acctttgaaa ataaaggtac
     1201 atatttatta ggtgcatttg agtttatatt taaggaaaaa aataaaaaac ttaggataga
     1261 agttgaaaga tattctaaaa aaggaaacag agtaatagtt ttagctcata gtgattctta
     1321 tatggaagat gataatattc ctgaagatat aaagccacta gcttttatat tgatattgga
     1381 taaaattaga gatgaagcta aggaaacttt agaatttttt tacaatgaag gtgtagatat
     1441 aaaaattata tctggtgaca atcctataac agtaagtgag gtagctagaa aagcaggtct
     1501 taaaacagct agtaatttta ttgatgcaac aacacttaaa aatgatagtg atatatacaa
     1561 agcagttgat aaatacagtg tttttggaag ggtaagccca caacagaaaa aacaaatgat
     1621 tttagcatta aaaaaacaaa atcatacagt agctatgact ggagatggtg taaatgatgt
     1681 gctagcactt aaagaagcgg attgtagcat tgccatggca tctggaagtg atgttactaa
     1741 gaatgtgtct aatttagtct tattagattc aaactttgca tcaatgccaa aagttgttat
     1801 ggagggaaga aaagtaatta ataacattca aagagcatct tctttgtttt tagtaaagac
     1861 aattttttca ttcttcttgt cgttattaac attattcttc ttcagtagac agtatccatt
     1921 tgttcctata caattatcac tcattggggc tgtaacagtg ggtataccat cattcttctt
     1981 agctcttgaa gcaaacaaaa gtagaatttc aggaaatttt ttactcaata tattaaaaaa
     2041 tgctttacca ggagcactat gtgtgacagt aaatgtaatt attgtttaca atatagttga
     2101 atatttgggt tatagttcaa gtgtattttc cacaatgtgt gctatattaa ctggtgtatg
     2161 tggtctttta atattaagac aacaatgttt gccatttaat aaagaaagat tatttttaat
     2221 agtaagtatg actattgcat ttgttattgg gattctattt ttaggtggat tattctcatt
     2281 tgtagcattg agtagagaat taattctcat aactatggca ttagcaatat taatgccaat
     2341 tatgataaaa gttatgttat ttgtcttaga tgagatatta gagacaattg ttccagattt
     2401 aaattaattt taaaatgata taaaaaagag cagttttagt tgaactgctc tttttagatg
     2461 tgtttaattt tatgtaagaa tatgtatttt tattaatcag ctatatatga gcaacagtag
     2521 tcaacaactt cattaacctt taagtcaaaa cttgaatcac taggaacatt aaatttttgc
     2581 ccttctttat aagttacaaa ctcattgctt ccaggcagtt ttacatccat acttccagca
     2641 agcatctcca ttatttcttc ttctctagta gaaaaagtgt attctcctgg caacattaat
     2701 cctaaagttt ttctttctcc attaggcagt attattactc tgctacttac cttaccatca
     2761 aaataaacgt ttgccttctt tactgcagta acattcttaa attcactcat tagataaaac
     2821 ctccaaaatt atttgtacat at
//
LOCUS       DAEQAF010000188         2783 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.192, whole genome shotgun sequence.
ACCESSION   DAEQAF010000188 DAEQAF010000000
VERSION     DAEQAF010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2783
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.192"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(25..480)
                     /locus_tag="KRN00_003583"
     CDS             complement(25..480)
                     /locus_tag="KRN00_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829398.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(708..1127)
                     /locus_tag="KRN00_003584"
     CDS             complement(708..1127)
                     /locus_tag="KRN00_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829399.1"
                     /translation="MDTLGERIVYLRKAKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPLNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            1426..1635
                     /locus_tag="KRN00_003585"
     CDS             1426..1635
                     /locus_tag="KRN00_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829400.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            1667..1876
                     /locus_tag="KRN00_003586"
     CDS             1667..1876
                     /locus_tag="KRN00_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829401.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(2093..2491)
                     /locus_tag="KRN00_003587"
     CDS             complement(2093..2491)
                     /locus_tag="KRN00_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1829402.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
BASE COUNT         1030 a          349 c          344 g         1060 t
ORIGIN      
        1 agacaactcc ttttttttat taaattattg tctattaacc aaaatagcta ttttagcatc
       61 tggattataa cttatctgaa ccatttgatt tttcttaaca tgttcaaggt cttcaccacc
      121 ataagctatt tgtaacttaa ctggtaactt accttgtttt ataatagcaa cgtactcttt
      181 tttacctttt ttctctaaac taatcaaatt gccaacataa ggtttaaagt tctgatactt
      241 tttactagaa tttcttatgt agaagaaagc accaacagca ataactaaat ttatgccaag
      301 tgtaacccaa gaattgattt taagcatagc tccagcgatt attatcacga acattaaaac
      361 gataggtaat atagctttct taagaagcaa tttacccatt atttcattag cctttttctc
      421 agggccactc atagtttttg atctagcaaa tgattgcgcg aatttgtctc ttaagcccat
      481 tttatcctcc taattttaat aaatatttag ttataataac gagatattac ttgaaactaa
      541 aaatttacta catttatatt atgtttgact tttgtataaa taattacatt caagtaaagc
      601 aaaatatact aattatttta tcataaaatt ataaaaaaga aaataaatga aataaaaata
      661 ttagaacaaa gaaatgatgt aaaatcgtat caaaagcaac ataaaaatta tttatctatt
      721 ttctcatctt tatttttgtt atactcaatt tttcctaaat ccttctcttt ttcatattca
      781 tgaagtttta attcaatcat accttctatt ttggctttat cataatcatt taactttcta
      841 aagttgttta aaagttttat ttcattagag tttatgctat taagtggata gtttgaggag
      901 gaatcgcaaa ttaaatctga tttatgtgat agattatctc catttaatag ccagtctact
      961 gaaacattaa atatctcagc tatagatttt aatatttcat aatttggttt tctaatgttt
     1021 ctctcaaatt tacttaagtt gtcacagccc aacatttctt ctagttcata ttgtttaagg
     1081 ttttttgctt ttctcaaata aacaattctt tctcctaaag tatccataaa cactctccat
     1141 tcaattaatg tcaaaaagac tttttaagat gtaaatagtt tcaaattaaa ggtcaaaatg
     1201 acataaaaac cattgactta aggtcaaaat gactttataa ttaacttaat gatacgaatt
     1261 tacatcctaa ttttagcaca aagtaatcaa aaaatcttat ttagtattaa ataaatttat
     1321 atacttaata tgtgtacata ttaaaaatat atactaaata gagggggtgt gtaagctaaa
     1381 ataatataaa agtaaatata aatcacttag aaaggaagtt gataaatgga tgctcgaaaa
     1441 aaatggatac cttttttggg agtgcaagtc aagcaaagac ttattgaatt aaatatgact
     1501 caaagggaat tagcgaagaa aataggtgtt aatgaaaact atttgtcagc tattttaaat
     1561 ggaagaagaa caggtaaaaa atataaatca tcaatttatc aattacttaa tatagaatat
     1621 tcagaagatg attaataaat agtatataaa gtaggtgaat attcttgtgt gtaaattgga
     1681 ttcagatggg gttatagagt gttgtagagc aattgatgat tttattacag cactcagtaa
     1741 tataaaaagc ttaaatatgg aaagattaaa tactttaact aaatattcta gtacatgttc
     1801 aatccttctt aaagagggga attatgaagg atgtacaatt gtgtatagaa agatgttgga
     1861 agaattaaaa acatgagtaa tgcatttctt aggaatataa gttatacata gagatgtatt
     1921 atatttttca aagtacttaa actaaaatat ggataagata atctaaatat tataaatgtg
     1981 cttgaaatta gactatactt gtttttaaat aatccaatat ccatatttta gtaatatact
     2041 acaaaaaaag aaggttagta gatgatgtaa aatcgtatca aattatgtat gtttaaacca
     2101 ttttatcttc attattatta gaggaatgct tttttaagtc tttatattca gatatcttaa
     2161 gttcaagtat tccttctatt tttattttat cacgttcgtt tagttgtctg tatagattta
     2221 atatcgtcat ttcatcatta gtaacatgta agtaatcttc tttatcttct tttacactac
     2281 tattgacatt taccttctct ttaccataga gaagccagtc agtcgtaaca ttaaaataat
     2341 cagctattga cattagtata tcacaattag gttttctatc tcctgtttca tacttgccta
     2401 agttttcaaa ttttaaaata tccataagtt tacgctgagt aagttttttg gagtttctca
     2461 aataagcaat tctttttcct aaagtatcca caaaatacac tcctttcttt ttatgagtaa
     2521 tgtctaaatg acatttaaaa ttaaaaatat ataaatttat aatataaaac tactaaatta
     2581 aagtctaaat gacattttgc ttaaattaat atgctcataa tatgatttta acatattata
     2641 gttgaaaata tatggtttat tttgatttgt atatataaca ataggtttaa ttgttatata
     2701 aatgtaaagg ggtgtatgaa tagattgtat aaatttattt cgataaacta agattgcttt
     2761 ttgattgtct gtaaaagaga aaa
//
LOCUS       DAEQAF010000189         2778 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.193, whole genome shotgun sequence.
ACCESSION   DAEQAF010000189 DAEQAF010000000
VERSION     DAEQAF010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2778
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.193"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(312..1208)
                     /locus_tag="KRN00_003588"
     CDS             complement(312..1208)
                     /locus_tag="KRN00_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBH1829403.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            1349..2776
                     /locus_tag="KRN00_003589"
     CDS             1349..2776
                     /locus_tag="KRN00_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBH1829404.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
BASE COUNT          948 a          382 c          328 g         1120 t
ORIGIN      
        1 tcatactatt ttagctgttt acttgcttat ttaatagttt tatttctttg attaaatatc
       61 tttcagaatc taagccagat gtctcaaaaa aactgattta taatataatc attttttctg
      121 ctattcttat ttttccagtt ttagtttcat attaaaatat acttttcata gacactgcat
      181 tctttcatac tcattttcac atttaactat acaagtagtc ttactcattt atgtactata
      241 ctttattaat atttattaag aaaaactcaa agatttaaaa atatatattt tctataaagt
      301 atatttatga attatttcat atcttctttt aaaataacat tactaacttc tttatgttca
      361 tttctatact tagttggaga tatattataa ttccttttaa ataagcgact aaaataattt
      421 atgctatcaa agccacatct catagcaatt tctgtcatat ttaaatctgt ttcctttaaa
      481 taatatatag ctttatcaag cctgattcca tttataaaat cgattgtagt cttacctgtt
      541 atttgtttaa atgttctaca aaagtgatgt gcactcaagt tcacatgact agcaagttct
      601 tttaatgtaa ttttatccat atatttttct tctatcaaat caaagataca ttcaaatttt
      661 tccaaagaat actttctttt tataaattca tcttcagaat atattttatc aatatgactt
      721 cttaataaga gtactattaa ttgatagata ttagctttta tagataactc atatccaact
      781 tctttattgt gatattcatc aagtatagtt gtaatacatt ttaaaatcag agaatcattt
      841 tgaattaaat tattaaatac aatatgattt aaagccaatg gtgctaagta cttggtttgt
      901 aacaaatcga cttgattact aaaaaggaat gtgggttcaa tacgaatact atagaatttt
      961 aaattatctg ataagctttc taaataatgt aattcattac tgtttgctat tacaatattt
     1021 ccaggcacta ccttaaaatt atccaatcca cattcaagat atgctatacc atcaataaaa
     1081 taatatattt gtagatgctc atgccaatgt cttttaaagt ttgctccttt tttaatgtca
     1141 tcctttaaaa aaatatctat aaagttttct tgacctttcc tgttaaaata tgtattttta
     1201 tccttcatta ttcccccctc atcaaaatag tgctaattat aagcaatata gttattgtat
     1261 tcattatttc atatcgctat tatataaaat gtaactatca ttgtaaacat taacataatg
     1321 cagtcgttat aataaggagg taataaaaat gacaaactct tttaaaaaag atgataatag
     1381 aaaaaaaatc acagttttat ttgtagtcat tgccatgact tttatggcaa cattagattc
     1441 tagtattata aatgttgctc tcccagttct tgcaagcaaa ctaaatgtat ctctagcatc
     1501 tattgaatgg gtaatagcaa gttactcaat tattatttgt tcaacactat tattttttgg
     1561 aagacttgga gatattattg gtaaatcaag agtatttcaa gtaggtacta ttctctttac
     1621 atcagcttca ttactatgtg gattaagtaa ttctttaact ttacttatag tttgccgctt
     1681 tattcaagga ataggcgctt ctgcctacat ggcaaacaat catggaatta tcacagaact
     1741 atttccaaaa gaaagcagag gaaaagccct agggatttta gttactgcag ttgctattgg
     1801 aaatatggtt ggaccatctg tgggaggatt tattttgtca atatttgatt ggaatgttat
     1861 attttttata aatattccaa tcggtcttat tgtaatcttt ttaaatacaa aatttcttcc
     1921 taatagtaaa aaatcttcag aaaatatgga taaaactggt gctatacttc aatttttagg
     1981 aacaacatta ttttttagtg ctctaattag tgctcaacaa acaggattac taaatccata
     2041 tatattaatt gcactattat tatcaattat ttttattata ttatttttga tattagaaaa
     2101 aaaacatcct caaccgcttc ttgaccttga aatttttaga aattttaaat tttcattgaa
     2161 tttaatttgt gctcttacat cattcatttg tattgcatca tcaagtattt taattccatt
     2221 ttatttacaa agtactatga aacttccccc tattcaagca ggtttattta tgatactatc
     2281 acctttgatt ttagccattt tttcacctat atttgggaat atatcagata aaattaagtc
     2341 agaaaaaatt attttaattg gtcttctcgt tatgagtttt ggattctttc taatgtcaag
     2401 attgaaagaa agttctgccc ttattttatt tgtaatttat atatcgataa tatcaatagg
     2461 acaagctata tttcaacctg ctaacaatgc tttgataatg tcaagctgtt ctagaagtaa
     2521 gctaggagtt gtaggaagca taaattccct tgtaagaaat ttaggacaag ttataggtat
     2581 tactatttct acaacacttt tatataattt tatgagtatt aaagctggat atagggtcaa
     2641 tgattatgtg attaataatg ataaaatatt tgtatttgga atgagaaatg tttatattat
     2701 tgttacactt gtttgcttaa taggtgcaat attaattggc ttttatttat ttaaatataa
     2761 taaaaatgaa caatagtt
//
LOCUS       DAEQAF010000190         2773 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.194, whole genome shotgun sequence.
ACCESSION   DAEQAF010000190 DAEQAF010000000
VERSION     DAEQAF010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2773
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.194"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            155..1078
                     /locus_tag="KRN00_003590"
     CDS             155..1078
                     /locus_tag="KRN00_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBH1829405.1"
                     /translation="MGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKTKIY
                     SNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSKKAG
                     ALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDALGNQFFIRDKDT
                     SSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNGFTK
                     ALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNITIEN
                     AIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            1053..1880
                     /gene="panB"
                     /locus_tag="KRN00_003591"
     CDS             1053..1880
                     /gene="panB"
                     /locus_tag="KRN00_003591"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBH1829406.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHISIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGTFPQEKHSFSINESELEKLY"
     gene            1899..2747
                     /locus_tag="KRN00_003592"
     CDS             1899..2747
                     /locus_tag="KRN00_003592"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBH1829407.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIIDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
BASE COUNT         1105 a          333 c          454 g          881 t
ORIGIN      
        1 atggtaagat atttatggat ggtatcttgt tataagaact atactttaaa tgtttttaat
       61 tattttgtct tatgtaactc atatcctcag gaatgagatt agaaattaag atgttgtatc
      121 acaaagtgga ggtgatacta ttaaaatagg ctttattggt tctggaaaag ttggaacatc
      181 tttggcaaat tattttttat caaaaggtta ttgtgtttca ggcttttatg gaaggaatca
      241 attatcttta ttagaatcaa caaatttaac aaaaacaaag atttacagca atttgaaaga
      301 tataatttat gaaaacgata tattatttat tacaacatca gatgattcta ttgaaattat
      361 agacaaaaaa ctttccaaat ttaatttaaa acataaatac atttgccaca caagtggctc
      421 tttaaaatct agtatattgt tctgttcaaa aaaagcaggt gcattaattt attctatcca
      481 tcctatattt gcattttcca ataaaaatac caacataaaa aaaatgaaag acatttgttt
      541 ttccatagaa ggtgataatg aacaagatga tttagttatt caaaatttca tagatgcttt
      601 gggaaaccaa ttttttataa gagataagga tacttcatcc acttatcatt tagctaatgt
      661 tttagtttca aatttagtat tatctttact agatatagga gtaagttact ttattaaatt
      721 aggtttatct gaagaggaat ctttaaaagc tatcagtcct ttagtaaaaa aaaatataga
      781 aaatatactt gataatggct ttactaaagc tcttactggt cctgtttctc gtggagatat
      841 aacaccaata agaaaacatc tatctgtatt ggataaaaaa gatgaggata tttacaaaat
      901 actatcctta aacctactaa aaataattgc cttaggaaat gacaattcat taaaaggtat
      961 aaaaaatatt actatagaaa atgcaatcga aaatttaata agtaaatctg aaaaatacaa
     1021 agaaatttac aaacttttag gaggaaaaaa cgatgaaaaa taccatacag acttttaaga
     1081 atgctaaata tgaaggaaaa aaactatcta tgcttactgc ttatgactac tcaattgcaa
     1141 aaataatgga tgagtgtgat ataaatggta ttttaatagg agattcatta ggaatggtca
     1201 taaaaggtga agaaaacact ctatctgtta ccatagacga aattatatat catacaaaag
     1261 ctgtaaaaaa tggtgtaaaa aatgccttaa tcgtaagtga tatgcctttt ctatcttacc
     1321 atatttctat agaagatgca gttaaaaacg ctggtagact tataaaagaa ggaggagctc
     1381 atgctgtaaa gttagaaggt ggctcaaacg ttataaagca aatagaaagc attgtaaatg
     1441 ctcaaatacc tgtaatgggg catttaggat taactcctca atcagtaaat tcatttggtg
     1501 ggtttaaggt tcaaggaaat accagtgaaa cagcaagaca acttattgaa gatgctaaat
     1561 taatagaaaa agcaggtgca ttctctattg tccttgaagg agtgcctacg aaaatagctg
     1621 agatggtaac taattctatt tcaattccta caataggtat aggggcagga attaactgtg
     1681 atggacaaat tttagtttat caagatatgt tgggaatgtt tggagatttt gttcctaagt
     1741 ttgtaaagca gtatgcaaat ataggagata taatgaaaga ttcaattaaa aattacatcc
     1801 tagaagttaa tacaggtaca tttccacaag aaaaacacag cttttcaata aatgaatctg
     1861 agttagaaaa attatactaa tattaaggat ggtacaaaat gcttgtaaaa gaaattaaat
     1921 tactaagaaa tataatcaaa gattggagaa aacatggcta ttctataggg cttgttacaa
     1981 caatgggatt tttacatgaa ggacaccaaa gtcttataaa aaaagctgta aaagaaaatg
     2041 ataaagtagt agtgagtgta tttgtaaatc caactcaatt tggaccaaat gaagatttta
     2101 atagctatcc aagagatata gataaagatt ttaaatattg tatggatagt ggagcaacag
     2161 tagtctttaa cccatcacca gaagaaatgt atttaaaagg taattgtact accattaatg
     2221 tttctggact tacagatttt ctttgtggag ctaaaagacc tgttcatttt ggaggtgtct
     2281 gcctagttgt ttcaaagttt ctaaatatag taacacctga taaagcttat tttggagaga
     2341 aggatgccca acaattagct gtaattaaaa gaatggtcaa ggatttaaac atagatacag
     2401 aaataatagg ctgtcctata attcgtgaaa atgatggatt agcaaaaagt tcgagaaata
     2461 catatctctc tgaggaagaa cgaaaatctg ctctaatatt aaataagagc ttaagtttag
     2521 caaaagaaga attagtaaaa ggcaatctaa atccagagaa tataaaagaa ttaataacag
     2581 ctaaaataaa ttctgaacac ttagcaaaaa tagactatgt tgaaattata gatagtgaga
     2641 cattacaacc tgttaagcaa atagaacatt ctatacttgt ggcaattgct gtgtttatag
     2701 gaaaaaccag actaattgat aattttacat ttgagttaaa tatatagtct ataattttat
     2761 ataatatatc taa
//
LOCUS       DAEQAF010000191         2719 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.195, whole genome shotgun sequence.
ACCESSION   DAEQAF010000191 DAEQAF010000000
VERSION     DAEQAF010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2719
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.195"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(253..1065)
                     /locus_tag="KRN00_003593"
     CDS             complement(253..1065)
                     /locus_tag="KRN00_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1829408.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(1141..2559)
                     /locus_tag="KRN00_003594"
     CDS             complement(1141..2559)
                     /locus_tag="KRN00_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBH1829409.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
BASE COUNT          955 a          483 c          277 g         1004 t
ORIGIN      
        1 atatttatat atattttgta tattaaatac aattatttat aaagtcttta ataaaaattt
       61 ataaatagag catctttaga aaactattat aataaaaaaa taagaggctg tctaaaaata
      121 tagataagcc ttttttcata atcgtaatta taaaaatata cttgatttca tatgaaaaag
      181 agtgtctcat aaactaaaat gtttactttg agacaccacc ttttttattc ttatttatac
      241 tttgtagaca tattataaca tgcgtttcac tggtatctga acttctgtca accagtcttc
      301 ttcactctct ttattccata taccatctat ataagattct ctaggatttc caaccacttt
      361 atatttattg tcctctatcc atttaaatgc atctgcgtaa gtttttccta atgttgaata
      421 tggaccattg tgtaatatac aaactgcatt ttcaactgca tctaattctt taaattttaa
      481 tatatccgta tcttccttta aatcatttat agcttgacac atttcaacat ccatatcagt
      541 ctctctatat tcaccatcat gatatatatt aaaacaataa tcaggaactg cacatgtaca
      601 ccctgttttc atcatttctt cagccattac atttggaaat agattaaaaa gttcatcata
      661 cccctttaac acttttctca tagaagcaac tttaactttt ggtaaagact taataattac
      721 atcattcata ttgacttctc ctttcaaatt cataaggtaa ttacgtagtt taattatttt
      781 atattcttca cttttaatta catccaacat ttctttttct ttattcatta aaatattttc
      841 aacttcttca ggattttcta cagctttttt tatctcagct aatgataaac ccatttgttt
      901 taaagttatt atctgatgta atttaggtaa ttgctctgtt gtataatacc tatattttgt
      961 aaattcatct acatattctg gttttaacaa ccctatatct tcataatacc ttaatgtctt
     1021 tgtagttatt ttatttattt tagaaaacat tcctatagaa aacatctcat cacctgcgca
     1081 ttagatttga ttaatttaag tttaaacttt ccccttaggt taaagtcaat acaaaataaa
     1141 ttataattgt attaattctt caattctatc tccactcaat accaaaatat cccctgtttt
     1201 tataatggtt gaacctttag gtattaaaac ctgttccttt ctttttatca taactattaa
     1261 tatatcgtct ggtatattag aatctattat actcttatta gcccatttat taccctcatc
     1321 aacatttact tcgataagtt tagagctaat ttctccatca taatcattaa atgtttttaa
     1381 tacaggtgta ttatcatcaa ctaaatccaa ctttctggct acagttggta tcaatgaacc
     1441 ttgtattcct actgaaagca acgctataaa aaatattata tggaatatgt cattctctat
     1501 ggctactcct tgagtaacag cataaattgc aaaaactact gaagccgcac ctctaagacc
     1561 tacccacgat atgaataatt tttctttatt tgagaattta aattttgcta gaactataaa
     1621 tgttgctaat ggtcttgcaa taactatcat gaatatagat atggccattg ctataccaaa
     1681 tacatttggt aacttagaag ggaaagataa caatcctaac ataaagaata acattatttg
     1741 cataatccat gaaattccat caaagaaatg aaccaaactt tttttaagag gtatcctact
     1801 atttcctata ataatacctg aaatgtaaac acttaaatat ccatttcctc caagatactc
     1861 gctaaatgca taagaaagta ttgcaatagc tgttataaat atagtataaa atccttctat
     1921 ctcgaagttt gaatgtctta aaatataaac agataatttt gctagtataa atcctatagc
     1981 taacccaaaa gctatttgtt ttattaccat tggtgcaata agttctaccc cagaattatt
     2041 catcaatgtc aaaagaatta gtgtcaacat atacgctatt gggtcattac ttccactttc
     2101 aacttctaat aatgatgcaa gtgaaccctt taagtttagt ttttgagaac gcaacacagc
     2161 aaacacagat gcagcatctg ttgaagctgc aattgcccca attaataaac cttcaagtaa
     2221 actagttcct attaccatgt ggcaaaacat acctgtaacg ccagccgtaa ttattacacc
     2281 cagtgaagac attaatatag aaggtatagc aacaggttta gccatattcc agtttgttcc
     2341 aaaccctcca aaaaacatta taaatattag tccaatagaa cataattgtt ttgttagttc
     2401 atagttatca aaatagattc ctaccatccc atcagaccca aataacatcc ctagtaagat
     2461 aaaaatcaat aatattggta ctccaaattt atacaatacc ttgctagaag ttatacaaat
     2521 caatagtact aacccactta taatcattaa ttctgtcata gcatcaactc catttcatat
     2581 aaattttgta gattaattta catctacaat tttattactt attcaaatat aacatgacat
     2641 aaattttata agttatggta cataaagttc aacaaaaatt tcacaataca ttaaaatgtg
     2701 agtgttatac ttaaattta
//
LOCUS       DAEQAF010000192         2623 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.196, whole genome shotgun sequence.
ACCESSION   DAEQAF010000192 DAEQAF010000000
VERSION     DAEQAF010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2623
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.196"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            453..932
                     /locus_tag="KRN00_003595"
     CDS             453..932
                     /locus_tag="KRN00_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1829410.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAVNNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            929..1708
                     /locus_tag="KRN00_003596"
     CDS             929..1708
                     /locus_tag="KRN00_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829411.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANNVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEDYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNEFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(1958..2458)
                     /locus_tag="KRN00_003597"
     CDS             complement(1958..2458)
                     /locus_tag="KRN00_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1829412.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNTINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELKLI"
BASE COUNT         1029 a          361 c          317 g          916 t
ORIGIN      
        1 aaaataatga catttctaac tcttaattct catttaagtt tcattgtttt ttcttaaaag
       61 cctactttta gtcaagatac tgttatcttt actcattatt taaagaactt attttaaatc
      121 tgtacatgaa gtaaataatc caaaagcatt gttattctaa ctactcaaca ttaaatactt
      181 actattttct aattactcaa tataaacact tactataaaa ctaaatacat aaatggcttc
      241 taaagtttaa tatatctaca tggctttata tatgacagga aaaatactag aaaaaatata
      301 ttatagaata cttgtatata ataggcaaaa ctttcaaact taaatttatc aaataatcat
      361 aaaaaaagtg aaccatctat agtaaaattt tatctaataa gtgaaaggca aaaaagtagc
      421 gctacgattt gcatagaagg gaaggaactt agttggataa aactacattt acaaacaata
      481 tacttgaatc agaacagact ttgtatcgag tatctaagtc tattctagga aacgaccaag
      541 actgtgaaga tgccgtcaac aatgctattt taaaagcata tgaaaagttg gattctctta
      601 aggaagaaca atactttaaa acatggctga ttagaatagt cataaatgaa tgtaattcat
      661 taagacgcaa acgattaaaa tctctatcat ttgaagatgt cttcaaaaac aaaaaaattg
      721 atgaaaaaga tgactatagc gatttgtata ctgctattca aagtctacct aaaaaaatta
      781 aaattccaat agtcctttac tatattgaag gttattcagt agatgaagtt aaggaaatat
      841 tagatatacc tcaaggaact gtaaaaagta gattatcaag aggaagaaga ttattaaaaa
      901 ctaaattaga aaacacggag gtaatcatat gaataaaaat atattaaata attcgtttcc
      961 agaagttcca gaaagttttc ataatagttt aagtaaaaca ctaaatagtt taccagaaag
     1021 agaggaaaat tataaaatga ttaataataa aacacacaaa ttaccattta gaaaaggctt
     1081 agttgcaact ttagccatta ctttgatatt gagcacaaca gcccttgcag taggacatat
     1141 atatagtttg gttggaaaat caagtactaa ggctacctat acatctatcc caactacaga
     1201 acaagtaaaa aaagacttta actttacccc taatatagtt tctgaattta gtaatggata
     1261 taaatttaaa ggagcatata ctgtaaataa aaaagcattt gacaaagaaa ataatgtttt
     1321 aggaaaatca aaagcactta gttttgaata taaaaatggc aatgatgaaa tatctcttga
     1381 cacagcaaat aatgtacttg ggaagagttc tgacaatcta aaagttgtag atacttacaa
     1441 agatattaat atttcttatg aagcattcgc acaaaagttt gtaccagaag attataaaat
     1501 gacagaacag gataaaattg atgaaaaatc aggcaaatac acatttagtg tagggccaaa
     1561 taatgaatca gacaaagttg aagttaatga atttaagttt ttgacatgga aacaagatgg
     1621 agtttactat tcttttacag ttcaagactc aaatttatct atgaatgact tagttaaaat
     1681 ggctcatgaa gtaatagatg caaaataaac ataagtaata ataagtcgtt tatgagttta
     1741 ttatttatga ctttaatttt tttattagta aacatggttg tatcttccat ctttatattt
     1801 tctttaaatt taatatataa aattttagat atttagctac cttcaaaaga accattatta
     1861 aaaagccctt aaaaatattt cttttatatg gaattttaag ggctttaact ttattttata
     1921 caagtgtata tggaatttta aagactttaa ctttatttta tataagttta agctccattt
     1981 gaattacttc ttcttttaca ggtctatcat tccatgtaaa accactagat attgtattta
     2041 cctctacaaa ccctaaagat ttataaacat gaatagctct actattactt ttaaatacat
     2101 caagctcaat tttttcatac ccatattctt ttgataaatc aataatttgt tttaaaagac
     2161 tacttccgat acctttttcc ctatactctt taagaatacc catgcctaaa taaccaactt
     2221 tttcagtttt aggtaaaacg tcacaccaac caatacagtt atctgattct aaatcaatta
     2281 taaacagttg tggtaagttt ttatttatag tattttttat aaattcaact gtttcttcaa
     2341 aaggaaaggc ttcatccata gctagatatt tcctctcttt tgctatttta tcaaaagttt
     2401 gccaatacga ataaatatac ttttcttctg cctttataaa ttttatgcct tctatcaact
     2461 taacatttcc cctttttaat ttgtgattgt agttaactta ttttatatga ttctagttta
     2521 taatgctata taaattacta catattagct taaaatatct ttgtatattt ctataaaatt
     2581 aaaaccaata tatctatctc ttgtatctct attaaaataa ttt
//
LOCUS       DAEQAF010000193         2563 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.197, whole genome shotgun sequence.
ACCESSION   DAEQAF010000193 DAEQAF010000000
VERSION     DAEQAF010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2563
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.197"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(213..1463)
                     /locus_tag="KRN00_003598"
     CDS             complement(213..1463)
                     /locus_tag="KRN00_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBH1829413.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1495..2436)
                     /locus_tag="KRN00_003599"
     CDS             complement(1495..2436)
                     /locus_tag="KRN00_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBH1829414.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
BASE COUNT          768 a          493 c          240 g         1062 t
ORIGIN      
        1 aaccttataa atatacaaat acaattatat gaattttcat cctcaattat agcatagaat
       61 atgactatct atatcctaaa attatccatt tctaaaaaaa aggtaactat tattaagaat
      121 atcaacttat agaatttata ttccacatac gattttcaat caaaaaaaca agggctaaaa
      181 agtgaattgt gcacttttta gccctttatt aattattcat ttatttcatg taagaataga
      241 ccacatctta ctttaggttc aaaccatgtt gacttagctg gcattatctt atttgcatct
      301 gctactctta ttaaatcttc aatactagta ggatacattg caaatgctac tttcatatct
      361 tcattaactc ttttttctaa ttcttcaaga cctctaattc caccgataaa atcaattctt
      421 ttatctactc taggattatc aattcctaaa atagcatcaa taacatagtc ttgtaatata
      481 gaaatgtcta atgagtcaac agggtcttct atttctaata aatttttatt tgctttcatt
      541 ttataccact tatcacctag gtacattccg aaagttcctt ttttgtcagg tttatatttt
      601 tcttttcctt ctatttcttc tagttcaaaa ttttctttta ttttatttat aaattcttcc
      661 tcgcttaaac catttaagtc tttgataacc ctattataat ccaaaaccat taaattctca
      721 tctggtgcaa tcattgctat gaagtaatta aattcttctt ttccagtata atttggattt
      781 ttagctctca tttctttggc tacattttct gctgaagctg tcctatgatg accatctgca
      841 atgtatagat aatctaattt ttcaaattta tctactaggt tatctattat atcatcatta
      901 tcaatcttcc atactgtatg ctctatcttg tcatctgtta tgaaatcata taaaggttca
      961 ttattatcca taaaatcatt gattatatca tctatcaccc tttgatgttt gtaagttaca
     1021 agtatagttc ccgtattagc atcacagtat tttatgtgtt tagttctatc aatttccttt
     1081 tctggtcgag tgtactcatg tttttttatt gttccattca agctttcatc aactgatata
     1141 catgctacta taccaacttg agctctacca tccatgattt gtttatatat atatatacac
     1201 tctttgtcat cttttactag aatttcttgt tttcgaaact catctaaatt ttctcgcgct
     1261 tttaaataaa ctttttcatc atataaatct atattttcat ctaaatcaat ttctgattta
     1321 tctatatgca aaaatgaata tggattccct tctgcaattc ttctagcttc tttactattc
     1381 ataacatcgt aaggaagtgc tgctacttta tctactatat atttatttgg tctaatcgcc
     1441 ttaaatggtt taatcgttgc cattactaat ttcctcctaa ttatacaaaa tattttataa
     1501 tgctacccct attagattgt tgaagtcaag aaagaaatct tgaatcacat ttactatttc
     1561 gtctcctatt ctttcttgag cttctactgt agatgcccca atatgaggtg taggagaaac
     1621 tcttggatga tttactaagt ctaaatttaa tgtaggttct tgttcataaa catctatagc
     1681 agctgctgat aatttacctt catctaatgc ttttagtaaa tctttttcat caactaaacc
     1741 gcctcttgca cagtttatta aataagcccc tttcttcatc ttatttattt ctttttcagt
     1801 tattactgcc cccttattct tatcaaatgg tatgtgtaaa gataagaaat ctgcattttc
     1861 taaaacttct tccatatcac agaatttata attgttaaag ccttgcgcct cacccattat
     1921 gtcagtatat ataacattca tacctaataa ttctgctctc tttgcaactt cttttgcaat
     1981 tcttccaaaa cctataagtc caagtgtctt tccattaatt tctgtacctt tatacttttt
     2041 cttctcccat tttccatctc tcatagttac atttgcagta tttatgaatc ttgcaagaac
     2101 aaataattga cctattgtaa gctctgcaac agatatactg cttgcatttg gagtattcat
     2161 aacttttatg ccattagctt gagcatattt aacatctata ttatccagac ctactccacc
     2221 tcttactatc aacttcaact ttttaccctc taatgcttta tctattacat ctttagtaac
     2281 tttagtagct gaacgtacta caagtacatc aacatcttta agtttatctc ctaaaacatc
     2341 tttttcataa aactgctcta tcacattaaa atctaactct ctcaattttc tcgctgcttc
     2401 tttctctatt ccatcagtaa ctaatatatt atacataaca aactcctcca atttttattc
     2461 acttaatttt tccaattttt attttttaaa gtattttcat caataaaaaa ctttacttaa
     2521 ttcaactttc tgtttatata attttcaaaa tattttttta tta
//
LOCUS       DAEQAF010000194         2388 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.198, whole genome shotgun sequence.
ACCESSION   DAEQAF010000194 DAEQAF010000000
VERSION     DAEQAF010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.198"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            180..497
                     /gene="trxA"
                     /locus_tag="KRN00_003600"
     CDS             180..497
                     /gene="trxA"
                     /locus_tag="KRN00_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBH1829415.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            complement(704..1978)
                     /locus_tag="KRN00_003601"
     CDS             complement(704..1978)
                     /locus_tag="KRN00_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBH1829416.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVMD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKPFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
BASE COUNT          860 a          306 c          335 g          887 t
ORIGIN      
        1 ttaagaaaaa aataaaatat attagaaata tttagtctca taaatattta atcttataaa
       61 tctatttatc ataatattaa atctattaaa aataggcggt tacaaaaaag tgcctaattg
      121 aactgttata tagggcgtag tatattaata tcaagaagat aataaaggag atgtatatta
      181 tggtaaaaat aataaataat aatgaattta taaatgaagt agaaaataaa gatggtttag
      241 tagttgtaga tttctttgcg acttggtgtg gaccttgtaa gatgctatca ccaatatatg
      301 aagctttagg aaatgagatg gttgaaaaag caaacttctt gaaggtggac atagaccaaa
      361 gtatagaatt agctcagaaa tttgaagtat ctacagtacc aactatgcta atatttaagg
      421 atggaaaacc tgtagataga ttaataggtt ttatgcctaa ggagaattta aaaaacaaaa
      481 ttgaatcata tatgtaatta aagtaaattg aagtaattaa aataaatctc atatataaac
      541 aaaaaaactc attgtaatga gttttttgtt tgtatagtgt aaaatagttt gtatagttac
      601 aaatgagtgt ctaattgcta atgaaattga ctgttgatat aatttgcttt tttgtgaaaa
      661 caaaactact ctctatttat tgataaaaaa gaatagaaaa aacttattta aaagccaaag
      721 ttttaatagc atgtataaag ctatccacct catcaaaagt attgtacatt cctaagctta
      781 tcctaacaag acctacagga ttttccctca taaatctgac gtatgcctct tttggattta
      841 tacctaataa tttttgtaca taaatatctg cacctactac tccagctcca gtttctattc
      901 caaagttatc aactaaatat tttgctacat ctttgtaata catattactt atattaaaag
      961 atatatttgg gataattaca ttatttgatt tatctccata tattattata ttaggtattt
     1021 tactcatttc ttctttagca tataaaaata attctctttc gtattttgaa attctgttta
     1081 gaccaatttt atttaaagtg ttcagtgctt ttcccattgc aagagttcca aaatactctg
     1141 ggtatcctgc ttcaaaacgt tggggtacgt ttgcatatag tattttgtta tcatttacaa
     1201 atttggtaga acctgagcca tatagtacag gattaaattt ttcaaagaat tttttaggtc
     1261 ctaccagagc tcctccattt agtggagaat aacatttatg agcactaaaa acaacaaaat
     1321 ctatatgctc atcacattca tgtggcatca ttgaaaaagg tttatgctga attacttgca
     1381 caatatccac caatatcttt gcaccatact tatgagctat tcttgctatt tcatatatag
     1441 gagtggttat acctgtgaca ttactagctc ctgtaactgt aacgagagat acattaccag
     1501 cataattttt aagtatattc tctaattgac ataaatcaag ttctcctttt tctgtaattc
     1561 caacaacttt tgtaggaaaa ttaactttaa aaggcaggta attagccata tgctccattg
     1621 ctgtggtaat aacaaattta tctggatttt catctttaaa aaattttgct aagaagttta
     1681 ttccttctgt agcatttttg acataaataa cagaatcctt ttcttcgtct ccatcaataa
     1741 gtttgaggat agtagagcgt acattttcat attttaaagt atttttttct gagattattc
     1801 ctggagcatt aatataagta agccaaggaa tctcacagtt taagttatcc attacgtttt
     1861 ttaaaactaa tggagtggca gagttgttaa aatatattct tttaacagtt tcaccatttt
     1921 tagttttaac tttaagattt gcaccttcaa tgtatttaga tacatccatg aattgcataa
     1981 aaaaacccct tatctaataa actattctgt tttttattaa aaaagctcaa gttttaatca
     2041 agagcttgtt taatatatgt tatgttttta taaggggttt tgttaattaa ttcttgttga
     2101 gatgtttatt aaattacacg aaaatgagct acagttgggg gaaactgtag ctcacttgat
     2161 tttgggggag ataggttgaa cttattgttt atccgtatca tatttttagt atagtcactt
     2221 attttaattt atatacattt ttttataaat tttacataaa atgttaaaca ctaattagaa
     2281 ataattatga atatgactaa taaagttgta aaaatagtaa agaaattgat tagaacataa
     2341 tggaaaatat attgtatata attagaaaaa aagattttat atgttata
//
LOCUS       DAEQAF010000195         2266 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.199, whole genome shotgun sequence.
ACCESSION   DAEQAF010000195 DAEQAF010000000
VERSION     DAEQAF010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2266
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.199"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(140..268)
                     /locus_tag="KRN00_003602"
     CDS             complement(140..268)
                     /locus_tag="KRN00_003602"
                     /inference="COORDINATES: protein motif:HMM:NF016296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829417.1"
                     /translation="MEYIQFICKNTVVINGKDIPVSKYRMANLKKKLTYVLGDVLC"
     gene            complement(407..1117)
                     /locus_tag="KRN00_003603"
     CDS             complement(407..1117)
                     /locus_tag="KRN00_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1829418.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKNTVVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
BASE COUNT          901 a          309 c          172 g          884 t
ORIGIN      
        1 ataatagcaa ttactatgct actatttagg gttaatctat tctttcttaa ctcactaaat
       61 tcatttaata aaaattttaa tacaatccat tctatcgtcg tagaaaatat aggtaaaaaa
      121 atccaaaata catttatatt taacataata catctcccaa tacatatgtt aattttttct
      181 ttaaattagc cattctatat ttactaactg gtatatcttt accattaata actacagtat
      241 ttttacatat aaattgaata tactccaaat taattaaata gctcttgtaa catttttaaa
      301 aatttattct ttcttaaatc actgaattca tttgataaaa attttaatac aattcattct
      361 atcgccgtag aaaatatagg taaaaaaatc caaaatacat ttatatctaa cataatacat
      421 ctcccaatac atatgttaat tttttcttta aatcagccat tctatattta ctaactggta
      481 catcttcatc attaataacc acagtatttt tacatataaa ttgaatatac tccaaattaa
      541 ttaaatagct cttatgacat ctaaaaaaat tatatttttc tagctctaat tctattttat
      601 ccatactatt tttagtataa taagtatcat ttttagtatg tatagtcaaa acctttttcc
      661 taacctctat atacataata ctattaatta aaattttatt gattatacct ttattttcta
      721 tcagcataaa attttctctt ttttttataa tatccgatat acaactcaaa atactttcat
      781 ttaaatctcc aaaatctata ggctttaata aatatctata agcccttacc ttatagcctt
      841 cctgtatgta atcaactatt gaagttataa atattatttc agaagtatca ttagtttctc
      901 taattatttt agccacatcc atgcctgtta gttgaagcat tttaatatct aaaaaaaata
      961 tatcaatacc ttctaaattt gtttccaata attcttctcc tgaattaaac tcaaatagtt
     1021 caatttgact agaaataccc tctaaggact ttaatataca ctctcttaaa aaagctattt
     1081 gtgtaatatc atcctcacag ataactattc tatacataaa cacccctcct tagacattag
     1141 atctgaaaac aaataaaata tcaatttata aataattatt tagttataca actaacatgg
     1201 tcatcaaata ctattattca cttaaaaaat caccccctat ttttagtatg ttaacaacaa
     1261 aataagaaga tatcttagat ttttaaaaac aattaatact taatgtagtt ttgtatacta
     1321 tttataggta attttttata tcattttaaa cattaaaatt attgatgttt aagaactatt
     1381 atattgatag taatatataa ttaatgatat caaaaatttt taattagact tctctcttat
     1441 tcaagatttt tctatataaa atctaagaat aaatagaaaa ctaacatcta accttttatt
     1501 ttttattttc gatctattta cttgaatttt aacataaatc tatcttttag tatatattaa
     1561 tcatgctgaa tttgtgatga catgtataca aaatatcgtt tagtattttc taataaaaaa
     1621 tattactgaa attaaaaatc tacaatagca tttaacaagt aaaaacatgt ttacacaaat
     1681 atataattta aggtctttaa aatagagtat gtattattct aaaaattagt tatagttatc
     1741 acataaaaat agaaaagaat tttcaaaaga tttaaagaac atatatactt caattgcaga
     1801 agatgtaatg ttaagtgagc tagcattctt cgaggaaaaa tagactcaaa aaattagaaa
     1861 atagaatcag gttttagatg atttaagtat ttattttcaa aaaagaaatt tgattctaag
     1921 ttaataaaga aatatttaaa aaaatcaaaa aattttctta aataagtaat aggttttgta
     1981 aaaatggaaa aatatcaaaa taagactatg atttttaaaa ctatagcctt atcaataaat
     2041 ttttatttaa agaacacaca taaatatttt taaacctaat ttatgtgaag ttttatgtat
     2101 tttttatata agtagtattc taatcttact catctaatat accaaaaaga ctgtaagtaa
     2161 gttcactttt atgcaaactt acccacaatc tcttttacac attaattcta tttattaaaa
     2221 ttaaaaatat ttactgctat tctacccaat aaagatgata ctgttg
//
LOCUS       DAEQAF010000196         2003 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.200, whole genome shotgun sequence.
ACCESSION   DAEQAF010000196 DAEQAF010000000
VERSION     DAEQAF010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.200"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..>2003
                     /locus_tag="KRN00_003604"
     rRNA            <1..>2003
                     /locus_tag="KRN00_003604"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          542 a          427 c          601 g          433 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaaggt
      661 ttccagggga aggttcgtcc gccctgggtt agtcgggacc taagctgagg ccgaaaggcg
      721 taggtgatgg acaacaggtt gatattcctg tactaccgat aaccgtttga gagaagggat
      781 gacacagtag gataagctaa gcacactgtt ggttatgtgt gcccaagcat tgaggcagtc
      841 aaagtaggca aatccgcttt gataatgctg ggatgtgatg gggagcgaaa tttagtagcg
      901 aagtagctga tttcacactg tcaagaaaag tctctatcga ggttaaaggt acccgtaccg
      961 caaaccgaca caggtgggtg aggagagtat cctaaggcca gcgagagaac tgttgttaag
     1021 gaactcggca aaatgacccc gtaacttagg gataaggggt gccaccatca ggtggccgca
     1081 gagaataggc ccaagcgact gtttaccaaa aacataggtt tctgctaagt cgcaagacga
     1141 tgtataggag ctgacgcctg cccggtgctg gaaggttaag gggatctgtt agagcaatcg
     1201 aagcagtgaa cttaagcccc agtaaacggc ggccgtaact ataacggtcc taaggtagcg
     1261 aaattccttg tcgggtaagt tccgacccgc acgaaaggcg taacgatttg ggcactgtct
     1321 caacaacaga ctcggtgaaa ttgtaattcc ggtgaagatg ccggatacct gcgacaggac
     1381 ggaaagaccc catggagctt tactgtagct tgacattggg tcttggtact acatgtacag
     1441 gataggtggg aggctttgaa accaggacgc cagttttggc ggagccatcc ttgggatacc
     1501 acccttgtag tactgggact ctaaccatag gccatgaatc tggtcttggg acactgtcag
     1561 gtgggcagtt tgactggggc ggtcgcctcc caaaaggtaa cggaggcgct caaaggttct
     1621 ctcagtacgg tcggaaatcg tacgtagagt gtaaaggcaa aagagagctt gattgcaaga
     1681 catacaggtc gagcaaggat gaaaatcgga cttagtgatc cggtggttct gcgtggaagg
     1741 gccatcgctc aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtc
     1801 cacatcgacg gggaggtttg gcacctcgat gtcggctcat cacatcctgg ggctgtagta
     1861 ggtcccaagg gttgggctgt tcgcccatta aagtggtacg cgagctgggt tcagaacgtc
     1921 gtgagacagt tcggtcccta tccgtcgcag gcgtaggaaa tttgagaaga cctgtcctta
     1981 gtacgagagg accgggatgg acg
//
LOCUS       DAEQAF010000197         1955 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.201, whole genome shotgun sequence.
ACCESSION   DAEQAF010000197 DAEQAF010000000
VERSION     DAEQAF010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1955
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.201"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(54..524)
                     /locus_tag="KRN00_003605"
     CDS             complement(54..524)
                     /locus_tag="KRN00_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBH1829419.1"
                     /translation="MKYQVSLLAVKDIEISKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTIIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
     gene            complement(1258..1647)
                     /locus_tag="KRN00_003606"
     CDS             complement(1258..1647)
                     /locus_tag="KRN00_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBH1829420.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          613 a          325 c          142 g          875 t
ORIGIN      
        1 ttgaactagt tccactacaa ttaatttcta ctaaataatt ataatttaaa caatcattcc
       61 ttactatttt cacactgctt tacaaattca attggatgtt gaattatttt agaagtttct
      121 tctacagaat atccctcaga taaatatctt ctagctataa cttccataga ctctcctatc
      181 tcaataatat gcttatctgg gtcataaata cgcactactc tttgttgcca ttcatgtttt
      241 agtggcttat ggacaaactc tacatcttta taataattga gtttttcaat aaattcgtca
      301 aaatcatcaa cctcaaaata aagttccata ttatttgatt tttgtataat tgtatctgga
      361 ttaatccctg taagccatgc gaagtcttct tgtatagcaa atcctccttt aaatgttaca
      421 tttttaccta agtccaattc aatttcttgc tcaaataatt ctttgtaaaa tttttttgat
      481 atttcaatat ccttcactgc taataatgaa acctgatatt tcataaattt tcctcctaat
      541 tttttatttc tattttttca gtatcttcta ttaacatttt tttctctatc tcttcagtac
      601 cttttattaa tcctttattt ttactttttt aatatcttct attaacactt ttgtttctac
      661 ctattcagta tcttatatca atcttttatt ttttcaatat cttctattaa cacttttatc
      721 tctatctatt cagtactttc tatcaatctt ttgtttttat tttttcaata tcttctatta
      781 atacttttgt ttctacctct tcagtatctt atatcaatct tttatttttt caatatcttc
      841 tgttaacact tttatctcta tctctttaat atcttatatt aatcctttat ttttattttt
      901 tcaatatctt cattaattcc tatttatttt atcatcttaa atacgaaaac actgtgtcat
      961 atttacaaaa tatatattat catctatatt aaagcttcac aatttatatt taaaaattct
     1021 ctttaattac actacctcta tttaaaaagc taccttaatt atacttataa gtaaaggtag
     1081 ctttttaaat ttaattaaat agaatatcca ctattaattt ttatttaatt tatttagatt
     1141 cacattatag tatcataatc cacttataat catttgtcat attacttaag tagactaata
     1201 tattacataa atacacttac atacacttta tattgatgct ataagaaata cgtttgctta
     1261 tacgtctttc tcctcttctt ttagattttt tatccactct tcaataagta aaatatcatc
     1321 tttgctcaaa ttaatatttt catgtaatga caacaataaa ctttttatag aagaatcatg
     1381 aatatttcta aaaaaatctc ttgtctcaac tcctatgtat tccttttctt taattaaaac
     1441 ttcataatgc gtatatttat ctatcttttg agaatttaga aatcttttta ctactaatct
     1501 agataaaaga gtcaaagttg tcgtttgttt ccattgatat ttttgctcca ttcctaaaac
     1561 aatatctcta gatgttactt tggaatctga tttccatata aatttcatta tctttaattc
     1621 tgattgtggc aactttttta tagtcatgat aaaaccttgc tactcagaat atagacaagc
     1681 aatatccata ataaaatttt tcgattaaat acatcttata cagatttata taagctcaga
     1741 cttataagat atttttcaat cttaatccta aatttagcta tttgtacacg gtaaatatat
     1801 ataaataatg tcaaaattct cttgtattat attgcttaat tttatgaaat attttgtact
     1861 cagctatcta ttttggatac ttgtccagta gctctccttt cttttaaact ctttgatttt
     1921 aaatatttgt atttcagtaa atcctacttc ctaaa
//
LOCUS       DAEQAF010000198         1944 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.202, whole genome shotgun sequence.
ACCESSION   DAEQAF010000198 DAEQAF010000000
VERSION     DAEQAF010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1944
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.202"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            128..244
                     /gene="rrf"
                     /locus_tag="KRN00_003607"
     rRNA            128..244
                     /gene="rrf"
                     /locus_tag="KRN00_003607"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            251..325
                     /locus_tag="KRN00_003608"
     tRNA            251..325
                     /locus_tag="KRN00_003608"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:283..285,aa:Asn,seq:gtt)
     gene            330..404
                     /locus_tag="KRN00_003609"
     tRNA            330..404
                     /locus_tag="KRN00_003609"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:363..365,aa:Glu,seq:ttc)
     gene            410..485
                     /locus_tag="KRN00_003610"
     tRNA            410..485
                     /locus_tag="KRN00_003610"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:443..445,aa:Val,seq:tac)
     gene            491..567
                     /locus_tag="KRN00_003611"
     tRNA            491..567
                     /locus_tag="KRN00_003611"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:525..527,aa:Asp,seq:gtc)
     gene            578..652
                     /locus_tag="KRN00_003612"
     tRNA            578..652
                     /locus_tag="KRN00_003612"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:610..612,aa:Thr,seq:tgt)
     gene            667..751
                     /locus_tag="KRN00_003613"
     tRNA            667..751
                     /locus_tag="KRN00_003613"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:701..703,aa:Tyr,seq:gta)
     gene            761..834
                     /locus_tag="KRN00_003614"
     tRNA            761..834
                     /locus_tag="KRN00_003614"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:793..795,aa:Gly,seq:tcc)
     gene            845..921
                     /locus_tag="KRN00_003615"
     tRNA            845..921
                     /locus_tag="KRN00_003615"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:879..881,aa:Arg,seq:tct)
     gene            931..1006
                     /locus_tag="KRN00_003616"
     tRNA            931..1006
                     /locus_tag="KRN00_003616"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:964..966,aa:Gln,seq:ttg)
     gene            1018..1093
                     /locus_tag="KRN00_003617"
     tRNA            1018..1093
                     /locus_tag="KRN00_003617"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:Lys,seq:ttt)
     gene            1096..1184
                     /locus_tag="KRN00_003618"
     tRNA            1096..1184
                     /locus_tag="KRN00_003618"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1130..1132,aa:Ser,seq:tga)
     gene            1213..1303
                     /locus_tag="KRN00_003619"
     tRNA            1213..1303
                     /locus_tag="KRN00_003619"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1247..1249,aa:Ser,seq:gct)
     gene            1312..1388
                     /locus_tag="KRN00_003620"
     tRNA            1312..1388
                     /locus_tag="KRN00_003620"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1346..1348,aa:Pro,seq:tgg)
     gene            1474..1549
                     /locus_tag="KRN00_003621"
     tRNA            1474..1549
                     /locus_tag="KRN00_003621"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1507..1509,aa:Trp,seq:cca)
     gene            1610..1686
                     /locus_tag="KRN00_003622"
     tRNA            1610..1686
                     /locus_tag="KRN00_003622"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1644..1646,aa:Pro,seq:tgg)
     gene            1693..1769
                     /locus_tag="KRN00_003623"
     tRNA            1693..1769
                     /locus_tag="KRN00_003623"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1727..1729,aa:Ile,seq:gat)
     gene            1773..1848
                     /locus_tag="KRN00_003624"
     tRNA            1773..1848
                     /locus_tag="KRN00_003624"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1806..1808,aa:Phe,seq:gaa)
     gene            1856..1932
                     /locus_tag="KRN00_003625"
     tRNA            1856..1932
                     /locus_tag="KRN00_003625"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1890..1892,aa:Met,seq:cat)
BASE COUNT          490 a          444 c          527 g          483 t
ORIGIN      
        1 tttgatgttc attcattaag atatatgtgc agtttttaga gtgttaactc taaaaaaaat
       61 aaaaaaagta ttgacaaaaa tagtaaaaaa tgttaatatt atacttgtcc tagcaacaag
      121 aaaaaaatgt ggttataata gcggagaaga tacacctgtt tccattccga acacagaagt
      181 taagttctct agcgctgatg gtacttggtg ggaaactgcc tgggagagta ggacatagcc
      241 acgtgaatgt tccaaggtag ctcaacggtg gagcaaccgg ctgttaaccg gtaggctgtg
      301 ggttcgagcc ccacccttgg agccattatg gctcgttggt caagaggtta agacaccgcc
      361 ctttcacggc ggtaacaggg gttcaattcc cctacgagtc accatttgtg ggatcatagc
      421 tcagctggga gagcacctgc cttacaagca gggggtcaca ggttcgagcc ctgttggtcc
      481 caccatttgc ggcctggtag ttcagttggt tagaatgcca gcctgtcacg ctggaggtcg
      541 agggttcgag ccccttccag gtcgccaaaa taaaaatgct ggtgtggctc aacggtagag
      601 cagctgactt gtaatcagca ggttgtaggt tcgattccta tcaccagctc catgtaaaac
      661 taatacggag gatttcccga gcggccaaag ggggcagact gtaaatctgt tgtcatcgac
      721 ttcggtggtt cgaatccacc atcctccacc aattaaatat gcgggtgtag ctcaatggta
      781 gagttctggc cttccaagcc agctgtgagg gttcgatccc cttcacccgc tccaaagaaa
      841 gcgtgggtgc atagctcagc tggatagagc aacgcccttc taaggcgtgt gtccggggtt
      901 cgaatccctg tgcgctcacc acatatatat tggggattag ccaagtcggt aaggcacatg
      961 actttgactc atgtatgcgt aggttcgagt cctgcatccc cagccaaata aaaatatggt
     1021 ctattagctc agtcggtaga gcacctgact tttaatcagg gtgtcccgcg ttcgagtcgc
     1081 ggatagatca ccaatggaga ggtgtccgag tggtttaagg agctggtctt gaaaaccagt
     1141 gacttcgaaa ggggccgtgg gttcgaatcc caccctctcc gccaaaaaaa tgactgaata
     1201 atgactgaat ttggagaagt actcaagtgg ctcaagagga tcccctgcta agggattagg
     1261 ctgggtaacc ggtgcgaggg ttcgaatccc tccttctccg ccattcaaaa acgaggtgta
     1321 gcgcagtttg gtagcgcaca tggtttggga ccatggggcc gggggttcga gtcccttcac
     1381 ctcgaccaac ttaagctttt agttcagttg gttagagtgc ccaactcagg gctagtaatt
     1441 ctagggtttg agtccatgaa ggttattctt cataggggtg tagctcagtt ggtagagcgt
     1501 cggtctccaa aaccgtgcgc cgggggttcg agtccctcca cccctgccaa ataaaaagga
     1561 cttgaaaaaa attggatttt agagtagtat aagatagtaa ataagatttc gaggtgtagc
     1621 gcagtttggt agcgcacatg gtttgggacc atggggccgg gggttcgagt cccttcacct
     1681 cgaccaagaa aagggcctat agctcaggtg gttagagcgc acgcctgata agcgtgaggt
     1741 cgctggttcg agtccagcta ggcccaccat ttgcccagat agctcagtcg gtagagcagg
     1801 ggactgaaaa tccccgtgtc ggtggttcga ttccgcctct gggcaccaga aatacggcgg
     1861 tatagcttag ttggctagag cgttcggttc atacccgaaa ggtcataggt tcgactccta
     1921 ttaccgctac catctaacta tatc
//
LOCUS       DAEQAF010000199         1822 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.203, whole genome shotgun sequence.
ACCESSION   DAEQAF010000199 DAEQAF010000000
VERSION     DAEQAF010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1822
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.203"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            151..1200
                     /locus_tag="KRN00_003626"
     CDS             151..1200
                     /locus_tag="KRN00_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBH1829421.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            complement(1350..1697)
                     /locus_tag="KRN00_003627"
     CDS             complement(1350..1697)
                     /locus_tag="KRN00_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBH1829422.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
BASE COUNT          678 a          248 c          280 g          616 t
ORIGIN      
        1 attacacatt actaaaaaaa ctaaacataa aactgaaaat tattattaag tttttgtaga
       61 aatattataa gtatagatac atttttgtaa caactacaat aaatatttaa tactatatac
      121 tattcgtatg tcttatggga ggtatttatt atgtttaaaa aaatagtcgc aatagcaagc
      181 tctatcattg taagtacaat atgtctaact ggatgtgatt ttaactctaa tgacaaaaaa
      241 gatgaatctt cttcgtctaa aaatctggat aaagtaacta tagcagaagt tactcactct
      301 gttttttatg ctccacagta tgctgctatt acgaaaggat tctttgaaga tgaaggtata
      361 aagattgacc ttataaatac ccaaggtgca gataaaacta tggcagcttt gatttcaggt
      421 gaagcaaacg taggtttaat gggtcctgaa gcatctatat atgtatataa tcaaaacaaa
      481 aacgattatg cagtgaactt tgctcaattg acaaaaagag atggtagttt tctagttgct
      541 aggaaaaaaa tgcctaattt ctcttacaat gatttaaaag gaaccgaaat attaggtggt
      601 agaaaaggtg gagttccact aatgactttt gaatatgttc taaaagaaaa aggtcttact
      661 attggagaaa atctaaaagc aggcaatgtt aatgtaagaa ctgatgtaca atttggtgta
      721 atggctggag cttttgcagg tggagagggt gactttacaa cagcatttga acctacagca
      781 acagcaatgg aaaaagaagg tagtggatat atagttacat ctataggaaa agattctgga
      841 gaaatacctt ttacagcata ctctactacg agatcataca tgaaaaacaa taaagattta
      901 attcaaagat ttacaaacgc tgtttataaa ggtcaattat ggattcaaca agcatctagc
      961 aaagaagtag ctaaggctat gcaacctttc tttgaagata tatctttaga agatttaaca
     1021 acagttgtag atagatataa atcaatagat gcatggtctc aaaatcctgt attaaaagag
     1081 gaaggtttga agaaattgat gactgttatg aaagaagcta aagaactaga taaggaagca
     1141 ccttataaag atatcgtaaa tactgagttt gcaaacaatg ctataaaaaa tattaaataa
     1201 aatatattag ttttagctag atattttctt gtttttataa tgaaaattaa caaaaatata
     1261 aaaagagcct tttaaaagac tctttttata tttgagatta aagtttatat aataaaatag
     1321 atattaaagt actaactgta cttatatatc tatcctctgt attctgctcc agcattaatt
     1381 tttgtaattt gaacggctac catttcttca ttgcttccat tagtaatttc atgccactct
     1441 cctgttggta caaatacagt atctccgttt tttacatcac attcatgctc accaagtttc
     1501 attttacctt ctccttttag gaacacaaat atttgttcac cattagggtg tctatgagca
     1561 ttaagaactt gattaggttt aaaataataa acttctgaag ttatatcgtt accagcaaat
     1621 actggtattt ttggaactgc tgtatcatta tattgagcta agcttccgtc taatagattc
     1681 tttttatttt catgcatact agaaatacct cttttctata ttatagattt actattatta
     1741 taccaatata agaaaatagt attctcactt tacacaatag gaataaaatt cttttatttt
     1801 taaatataag tataatacta tt
//
LOCUS       DAEQAF010000200         1789 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.204, whole genome shotgun sequence.
ACCESSION   DAEQAF010000200 DAEQAF010000000
VERSION     DAEQAF010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1789
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.204"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            23..385
                     /locus_tag="KRN00_003628"
     CDS             23..385
                     /locus_tag="KRN00_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829423.1"
                     /translation="MYKLIKNLKKNDIDTTLIENELYYRKAGTNKIVWTKADFDLYLS
                     KGVALTLAGAGTGVVGLLAGAIPGIGQYLAAAIVGAITMHLGSNITSGKIFKFKKMRY
                     NKGGAYVTKYYLQSVRNQ"
     gene            677..994
                     /locus_tag="KRN00_003629"
     CDS             677..994
                     /locus_tag="KRN00_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829424.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEILYRYVTGLEYIAIGLFTKRLDITIIAIILVATITVILYYLVRKRY
                     ITI"
BASE COUNT          736 a          191 c          234 g          628 t
ORIGIN      
        1 ataattatat tatacaataa caatatataa gctaattaaa aaccttaaga agaacgatat
       61 tgacactact cttattgaaa atgaattata ttatagaaaa gctggaacaa ataaaatagt
      121 ttggactaag gcagactttg atttatatct ttctaaagga gttgcattaa ctttagctgg
      181 tgctggtaca ggggttgtag ggcttttggc tggtgccatt cctggtatag gacagtatct
      241 tgcagctgct atagttggag caattacaat gcatcttggt tcaaatataa catctggaaa
      301 aatatttaaa tttaaaaaaa tgcgttataa taaaggtggg gcttatgtaa ccaaatatta
      361 cttacaatct gtaagaaatc aataggtgat aaaatgatta taaaatatct actttttgca
      421 attatctcag cactagtttt attcttttgt aataaaatat ttcaactaag taaattacac
      481 aagttcatta tattgtttgt ttcatttttt atactaactt ttgtagcatc atttattaat
      541 agataaaaaa taagatggtg gggttaacct accatctttt tctcatttaa tatttgtaat
      601 attttagata ctctttatac ttgtgttgct gatatacttt gattaagaaa agtaaattta
      661 acaggaggta tctgctatgg attttggaaa tatcaatctt atacttattg gaataatagt
      721 tataatagga actacaataa tatatttaat taaacctaaa actgcttttt gtagtaaaaa
      781 atattttaat aaattagaat caatatatgg aaatatagat aagaaaaaaa ctgttaaact
      841 agaaatactt tatcgctatg taacaggtct tgagtatata gcaataggct tatttacaaa
      901 aagattagat attacaataa tagcaataat attagtagct actataacag taatattata
      961 ttacttagtt agaaagagat atataactat ataaaatcta atagaattaa tatcaaaaga
     1021 aggtagcaac taatcaccag taatgtaaaa taatttgttt ttcaaagtta ataaaagtct
     1081 tctttatggc aatgatttaa atataatcaa atatcgtaac ggagattttt ttatgaataa
     1141 tttaagaaaa caattaatca aagaaattat ataagatgga gaacttataa aatctacaga
     1201 tataagtagt tttagtagta aacacagatg acttatttca aagagacaat agctacaagt
     1261 tatcctcatt ctgtaataca aaaatgttta atacattaga taagaaatac tttaaatatg
     1321 tttcatacaa ggactcaaaa gaattaataa gtgattttaa atctgtatat aggtcagtta
     1381 atgaataaaa atccttatcg actttagata aaatagatta aaaataatgt aaacagtata
     1441 cttcagaaat taaaacgttt ggaaataact ggaatgttgt agcatcagcc tttagtttta
     1501 ctaaaataag taatatctat aatatatatt acaagtataa tcgaaggatt taataaatat
     1561 ttcaaaaatg tctcaaaaac aaagtccaga tttacatcaa acgcttcact cttaaagata
     1621 ttattcttga caagcgaaaa tgtgatgaaa aaatggacta tgaaatataa aaattgatat
     1681 aatatataca atcatttatt catatctttt gatagtagaa tataatttta aaaattatac
     1741 cctaaaaatt tgctataatt gttataatat atataatttc caaaaatat
//
LOCUS       DAEQAF010000201         1771 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.205, whole genome shotgun sequence.
ACCESSION   DAEQAF010000201 DAEQAF010000000
VERSION     DAEQAF010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.205"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            233..1573
                     /locus_tag="KRN00_003630"
     CDS             233..1573
                     /locus_tag="KRN00_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBH1829425.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCV
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKMNKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
BASE COUNT          704 a          129 c          283 g          655 t
ORIGIN      
        1 taatatattt tatacctagt tatagataaa tttatatagt tattattaaa aaaagcaata
       61 aaaagtttaa ttcaatttag caaatttagt gatataatta aaaaagaaaa gaaatatgga
      121 cttatttgga ataattttga caatctattt actacacgtg tagagtcgta tataattaaa
      181 ttatacataa aatataaaaa aataatttag taatacgtta ggagaaagta ttatgataaa
      241 gtcaagctta ttttggaata ttttcattgc gatatccttt atgatagaat ggtttctttg
      301 taagaaaatg ctagattata caagtgagaa aaggatttct aacaaaaaaa taaacttttg
      361 tgtggtaggt attattgttt ttgctgacat aatatatttt tttgatgtac ctccaaatat
      421 aagagtaatt atatctatga taattactat tgcattttat aaaatctcat atgatgtggg
      481 gtttataaag tctgtattaa tatccttaat ttattggatg ttactaatcg ccacagatgc
      541 tttgagtata tctttaacag tttggcttaa ttctataaat gacatgagta gtatggggac
      601 gggagatata tacagaattg agtctataat attgggaaag atacttttga ttgtgtcttt
      661 gcttttatat agagccttaa agataaaact taatatagaa ataaataaaa ggacattatt
      721 ttatatagtt attcctatag tcgctaatat agcatctttt tttgtaattt ttgaatacat
      781 atttaatcca gggtctggta gcttaataca taatttccaa ttcgttatga tttctgttgt
      841 attgcttata tcaagtatca ctttagtttt aattgctaaa aaattacagc aatataatac
      901 tttagttgta gaaaacaata tgattaaaaa tactttgaag tatgaaaatg agtattatga
      961 agatatagaa aagaaatatt taaaaactag attactaagt catgatatga aaaatcacat
     1021 cttgtgtata aatgctatga ttaaaaaagg tattgatgtt acttcttatt taaataattt
     1081 gcaggtagaa attcagagta atgacttgtt atttaatact ggtaatttta tattagatgc
     1141 tatattaagt gaaaagaaag aggtttgtga taagaatgat atagaactaa aaataggaat
     1201 aaattttagt tgttgtgaag ctgttgaatt agtggatata tgtcatatat tttcaaatat
     1261 tttagacaat gcaattgagg catgtaataa aattgatagt ggaaatagag ttatttgtgt
     1321 taaaggtgat gttatgcaaa atttttattt aataagagtt gaaaatacta agatgaataa
     1381 gattattact aaaaatggag atattttgac agacaaaaaa ggttctcttc atggacttgg
     1441 aataaaaagt gtaaaaaact ctgtaaataa gtatggtggt aatgttgtaa ttgaatatga
     1501 tgataaaaaa tttgtagtta aaattgctat tccacttaga aatgtgaaga aagcagttaa
     1561 tcatgtgatt taaatgtata taaatttgat gtgtagaaat ttaatatata agaattaatg
     1621 tataaaagtg atgcatagaa gtttaatata taagaattaa tgtataaaag tgatgcatag
     1681 aagtttaata tataagaatt aatgtataaa agtgatgtat agaagtttaa tatataagaa
     1741 ctaatgtata aaagtgatgc ataaaagttt a
//
LOCUS       DAEQAF010000202         1675 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.206, whole genome shotgun sequence.
ACCESSION   DAEQAF010000202 DAEQAF010000000
VERSION     DAEQAF010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.206"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            104..838
                     /locus_tag="KRN00_003631"
     CDS             104..838
                     /locus_tag="KRN00_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBH1829426.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGNNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNMLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(981..1472)
                     /locus_tag="KRN00_003632"
     CDS             complement(981..1472)
                     /locus_tag="KRN00_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBH1829427.1"
                     /translation="MNNQQQEVYKKLDELSIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
BASE COUNT          629 a          196 c          241 g          609 t
ORIGIN      
        1 gtttatagaa acttttatta ttttatataa aagtgataaa aacttatatt ttgtatttaa
       61 tagagtgttg ctaagtgaat atatttaaaa tggaggaaac tttatgaaac aaaataaata
      121 tgatgatgat agatttttta ataaatacag taaaatggaa cgttctacaa atggattagc
      181 aggtgctgga gaatggcatg ttttaaaaaa aatgttacct gatttcaaag gaaaaagagt
      241 tttagattta ggatgtggat ttggatggca ttgtcaatat gcagttgaga atggagcaat
      301 ttctgctgtt ggagttgata tttcagaaaa aatgttaaaa gaagctagaa acaaaacgca
      361 acttgataat ataaattaca tatgtatgcc tattgaagat attaattttc caaaagatag
      421 ttttgatgta gttattagtt ccttggcatt tcattatatt caatcatttg aagatatatg
      481 taagaatata agtaattgtc tttcaaataa aggtaatttt gtattttctg ttgaacatcc
      541 tatatttact gcatatggaa gtcaagagtg gtactgtgat aaagatggaa ataatctaca
      601 ctggccagta gatagatatt ttgaagaagg agtacgtaag tcaaattttc taggagaaga
      661 ggttataaaa tatcataaaa cattaacaac ttatttaaat atgttaatga aaacaggatt
      721 tgaaatatta gaaattattg aacctcaacc agaagaaaaa ctgttagata caattcctga
      781 tatgaaagat gagctacgta gacctatgat gttacttgta tctgcaaaaa aaagataagt
      841 aaatataaat aatcattatt gtagaaaaaa agttgtagaa aataattaca ctaatggaga
      901 tgattatacc agtggtatta attacaccag tagtaaggag gcaaaagcat tcgttgcttt
      961 tgccattttt taagttgcaa ttatacttct acgtagtata tttcgtttcc attttcttct
     1021 ataagctttt tcatatcttc aaattttaaa aatacagtag cagtattatc atttggatgt
     1081 atacctattt tatccatttt taataaatcc ttatcaaata caacttttac aacagcctct
     1141 ttatcattta atataccaaa aggagtcaca gctcctttag taagtttcaa gtatttttga
     1201 agtctttctt ctgatgcaaa actaagaggt ttactatcaa tttgttgacg aatatctttt
     1261 aaatctgctt ttttgtcttt acctaataca actaaaaaat gttcttttcc tttagcatca
     1321 cgaagaaata ggttttttac aacaaattcc atatgtaatg tttttaattc ttccatttct
     1381 tcaattgtat aaactggtgg atgatttaca gcctcataag gtatgcttaa ctcatctaat
     1441 tttttatata cttcctgttg ttgattgttc atgatttcct cccattagaa atttatttta
     1501 tatataaata atattatcac agaaaacttt aaaagaaaac gttttatata atatagacaa
     1561 tagattatat ttttataaag aagcaagaat actcaataaa acttaaagaa attaaacaat
     1621 ttctaaaaat accttgaaaa tagaacctta tttgccattt ataaattata taaaa
//
LOCUS       DAEQAF010000203         1609 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.207, whole genome shotgun sequence.
ACCESSION   DAEQAF010000203 DAEQAF010000000
VERSION     DAEQAF010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1609
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.207"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            97..1533
                     /locus_tag="KRN00_003633"
     CDS             97..1533
                     /locus_tag="KRN00_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBH1829428.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          658 a          165 c          271 g          515 t
ORIGIN      
        1 taatttgcaa ttttacataa gtttgttaag tacataacta atttaagaat atgtatttat
       61 atattaaaaa tttattatga gggggacaat tttattatga aattctataa aagaatatta
      121 acattgactt taagtatttc ttttgtattt gcaaatattc aattagtaga tgcaatatca
      181 tctgtagaaa aaatacaagg aaaaaataag tatgaaatag caggtaaaat agcagataaa
      241 aatgcatata aaactgctat attaattaat actagtaact ctattgcaga tggattaagt
      301 gcaagtggac tagcaggagc tttaaatgcc cctatactat taactgaaaa aaatactata
      361 ccaactgaga catctgcaag attaaaaaat gtatcaaaag tttatataat tggaggaaca
      421 tattctatta gtacatctgt cgaaaattca ttaaaatcta agaaaatgaa agttgtaaga
      481 attaagggaa atgacagaat aaaaacaagt tataatgttg caaaagaaat aaattcaata
      541 aaaaaagtca atactgttat gctaaccaat gcatataaag gagaagcaga tgctataagt
      601 attgcatctg tagcagcaag agataaagca ccaataattc ttactaatgg acaaagtata
      661 cctttttcaa ctagtggttt aaagtcttat gtaataggag gaacagcttc aatgagtacc
      721 actttagtaa acaatactaa atctactaga ctagggggga gtactcgttt tgaaactaat
      781 aaagcaataa taaataagtt ttataaggat gctagagagt tttatatagc tggagcttat
      841 gaattaacaa atgcacttgt aggatcttct ttatcaaaac atggtccaat ggttttagtt
      901 aatgatggta gcaataaaag cattttaaaa aatgctaaga agataacttc tataggatat
      961 atagattcaa atatagtaca acagtgttta aatataacaa atggaattgg agatattaat
     1021 actggggttg taaaaaatgt taaacctact acaaagacta taaaagatgg aatgtataag
     1081 gttggaaaag atatctcagc aggtgaatac ttaataactt caaactcagg aagttatgct
     1141 tcttattatg aagttacaag tgatagtaca ggtaatgctg atagtatact ttcaaatgat
     1201 atttttagtg ggactagata tatcacctta aagaatggtc aatatattaa aattgaggat
     1261 tcaacaatga cattagcaaa gtatgctaaa gcccagaagg ccaagaatgg taagtttgga
     1321 aatggtatgt ataaaattgg attagaaatt cctgctggag aatatattat aatgtcaaat
     1381 tcttctgatg catattatga agttagaaat gatagcttag gtaatgcaga gggaatagtt
     1441 actaatgata ctttttcagg aagaagatat ataacagttg aggaaggtca atatttaata
     1501 ttaaatgatt gttatttaat tgaaaatgaa tagatgtaat tgtatttaat attaaatcat
     1561 atattttatt taaggaaaga tgttttaagt tttaatttaa aacatcttt
//
LOCUS       DAEQAF010000204         1574 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.208, whole genome shotgun sequence.
ACCESSION   DAEQAF010000204 DAEQAF010000000
VERSION     DAEQAF010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1574
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.208"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            76..1314
                     /locus_tag="KRN00_003634"
     CDS             76..1314
                     /locus_tag="KRN00_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBH1829429.1"
                     /translation="MNKGFYKLNSVVLNFDIKNDVNKIRFNHYIMRKENIQRLQGTLP
                     NGQFYMTVRRAATDLQLSISTISRLVKEFLDLGIIRLVSKGVKGNRSVYSYVSIEFNG
                     SLFDDSKYMELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYFSDDDVE
                     HNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFNDTCNEID
                     KRTNNSIENNQNKRPMRLSDISVLSDKGMTNKKNYFNHNHGIQKGTKSVTKKKESLNK
                     FNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEVKVAKWK
                     NTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSDYTTYDG
                     SVHERKKYENVRYWNPICEI"
BASE COUNT          668 a          141 c          267 g          498 t
ORIGIN      
        1 taaactattt tgttatttat ataaaaatac ttatctagtt actagcaatt attagtagaa
       61 atgggggaaa tagagatgaa taagggattt tacaaattaa attcagtggt attgaacttt
      121 gatattaaga atgatgttaa caagataaga tttaatcatt atataatgag aaaagaaaac
      181 atacaaagac ttcaaggaac tctgccaaac ggacaatttt atatgacagt gagaagagct
      241 gctacagatt tacaactttc tatttctact ataagtaggc ttgtaaaaga gtttttggat
      301 ttagggataa taagattagt gtctaagggt gtaaaaggta atcgttctgt atatagttac
      361 gtaagtatag agtttaatgg aagtttattt gatgatagta aatatatgga acttgactgt
      421 gtatgtaatg atgaatttat tgataatagt ggcatagagt ttgattgtga tagcaaagat
      481 aattctttta atggagatat aaatgtagaa actgtgcatt gcattaatga gtatttctct
      541 gatgatgatg tagagcataa ttataacaat ttccataaca aagatactat aaaggataaa
      601 gccatttcta atattagcac tatcaaaaaa tatattgatg aatcttttga tacaaataaa
      661 tcagaaaatt ctaacttaca acaggagtca ataaatttca actttaatga tacatgcaat
      721 gaaatagata aaagaacgaa taatagtata gaaaataatc aaaataaaag gcctatgaga
      781 ttgagtgaca tcagtgtttt aagtgataaa ggtatgacaa ataaaaagaa ttactttaat
      841 cataatcatg gtatacaaaa agggactaaa tctgtaacaa agaaaaaaga atccttaaat
      901 aaatttaata aaaaaaatat acagcaaagc attataaata tgctaaataa aaaatcaggt
      961 aagaatttta aaatcgattc tccaataagc ataaaactta tcaatgaaag gctaaaggaa
     1021 ggctatgtct tagaagattt ctacaaagtt attgaggtaa aagtggctaa gtggaaaaat
     1081 accataatgg aaatgtatat aagaccagaa accttgttta gctataagtt tgaatcctat
     1141 gtaaatgaaa acatatctat gaaaagtcaa agtaatgttc acccatgtaa agaaggcaat
     1201 agtaatgata gcagtaatta tatacattct gattatacaa catatgatgg cagtgtgcat
     1261 gagagaaaaa aatatgagaa tgtaagatac tggaatccta tatgtgaaat ttaattagtt
     1321 taagaatgta tttatgataa ataagatatt aatagagaat agtgagctat agcaaatgat
     1381 atatcaatag ttggtagtaa gttatattaa gcaagatatt actatcaggt agtgaattat
     1441 attgaacgat atatcaataa ttggtagtaa attatattaa gtaagatatt actatcaggt
     1501 agtgaattat attgaacgat atattaataa ttggcagtaa attatattaa ataagatatt
     1561 aatattggat agtg
//
LOCUS       DAEQAF010000205         1567 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.209, whole genome shotgun sequence.
ACCESSION   DAEQAF010000205 DAEQAF010000000
VERSION     DAEQAF010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1567
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.209"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(284..595)
                     /locus_tag="KRN00_003635"
     CDS             complement(284..595)
                     /locus_tag="KRN00_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829430.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(651..1244)
                     /locus_tag="KRN00_003636"
     CDS             complement(651..1244)
                     /locus_tag="KRN00_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBH1829431.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
BASE COUNT          576 a          206 c          204 g          581 t
ORIGIN      
        1 aggaagtata gaaagctaat ctaaagaagt atagtaaact aatttaggaa gtatagaaaa
       61 ttaatctaaa gaagtataat aaactaattt aagaaatata gaaaattaat ttaaagaaat
      121 acaatacatt aatttttgag taacattaaa ttaatgtaag taaaataatg ttcatatgaa
      181 gatttaaagg tgcattttct gaagctaagt atatgttgta gagtgttatg tctctctagc
      241 ctgtgaagtt taatagctca agaaaatgca ctatttatga tgattatttt gttttatttc
      301 caattttgga aataactatt ctaattaaat ctaaaattat accataaata agaaaagaaa
      361 gtatagatgc tatgtaccaa taaatcgaaa ttgaccctgt aattgttcta catgggattt
      421 gcatacctga atccataaaa acaaaaaaac tatcaactct ggaaataata gacaaaatag
      481 gatttaaacc tattagaaca atactttttg agtcttgacc aatttgatgc atataaatct
      541 caaataatgc aattaaaaaa aaccaaaatg taaaagattt aataattttt ttcatcaaaa
      601 tacctcacat aatataaatt ctgtttgcac tatttgctta ctacaactat ttatctccat
      661 tcagtcacat cacttaattg taatctaggt cttcttgatg gttcttcatc aggataaccc
      721 aaagatattg ctgccactaa ttgactatct gtatttaacc attcacataa ttcacgatat
      781 gcaaagtata catcacaaat ccaaagacta cctagaccta attccacagc tgtaagcgac
      841 atattctgaa ttgcagctcc aattgattgc atgtttgcca tttcatagaa tcgttcttca
      901 ggggatagct tttctaaagg tgatttacct aatatattta aaataaaaat tgttactgga
      961 gcttgtttca tgatttcaac tgtgtaattt gcaccagcga tatgttgacg acttcctgga
     1021 agaagcccat tatcattaat ttcattttga atacctttgc tcatggcttt aagcatagat
     1081 tctttttcct tttcagtgat gacaacaaaa cgccatggtt gcctgttttt agatgaaggt
     1141 gcatttattc cagcttcaat tattttctct atagtttcat gtgaaatgct ttgattttta
     1201 tattttctga tacttcgtct ttttgatata gaatcactta tcattttaag taacctccgt
     1261 ttattttttg gaaaaatcta tttaattttt attttctatt ttaattattt tagcattaat
     1321 cagaaaaaaa gtcattgatt ttagtataca attattaatg attatattaa gaattgtatc
     1381 aaaaagtatg tgattatact aagggattat attagacatt atatttaaaa ttgtatgaaa
     1441 ggttgtattt aatattatat tgagagagat atatattagg atttatatat attaagattt
     1501 attattatat tgagccttat attaaattaa ggactataat ttgaaaataa gctataaaaa
     1561 ctcaata
//
LOCUS       DAEQAF010000206         1552 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.210, whole genome shotgun sequence.
ACCESSION   DAEQAF010000206 DAEQAF010000000
VERSION     DAEQAF010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1552
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.210"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            240..1067
                     /locus_tag="KRN00_003637"
     CDS             240..1067
                     /locus_tag="KRN00_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBH1829432.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGNGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
BASE COUNT          585 a          169 c          223 g          575 t
ORIGIN      
        1 ataattttaa catgcccata aaatataata cccacaaatg ataaataata ctcaaaatat
       61 ctattgaaat aactatacat ccttaaataa cttaacttaa atctaaacat ttcaaaaact
      121 tcttaaaaat atgtaaaaat ttgatgataa agtagcgatt ttttcaaaaa aaatgtaata
      181 tagagttata tcttataata ttttagagat aaattttatc atagtgggga gaaatttgta
      241 tggatttaag caaaaaagta aaaattttag aaaatgcatc agatggcaaa agcgaatttg
      301 agatattaga atttgaaaaa cttgagggag cttctagccc attaatggca atgggattat
      361 attttgctag agaagctggt ttgaaagcta gacaaattaa gataaaatta aataattcat
      421 caataaaaac agaagctggt gcattatact attataaagg aaatatatct tctgaaacta
      481 agattggtgg tgttggaggt ctttttaaaa aaggaatatc aggagcactt actaatgaat
      541 caatgatgaa acctgtatac aaaggtactg gagaagttta tttggaacct tcttttagac
      601 attatttatt tatgagtctt gataatgatt ctataattgt tgataaagga ttattctatt
      661 gttgctctga tacaatagaa gtaaaagcat ttacacaaaa gaacttctca tctgctttac
      721 ttggtggtga aggcttcttc caaatagaat taagtggtac tggtgtaatc gttctggaat
      781 gtgttgtacc tcaaagtgaa attgtagagt atgaattgaa aaatggtgaa gaattaaagg
      841 tagatggtaa ctttgcaata gcaagaacat ctggtgttaa tttttctgtt acaaaatcag
      901 ataaatcttt aattggttct gctttaaatg gtgaaggttt cttaaataca tttactggta
      961 atggtacagt ttggctagct ccaactcaag taatgtatga aaaactaagt tttggagcaa
     1021 tgcctactaa tgataatatg aataataaag tttctaagca aaaatagttg ttttataaat
     1081 atttattaaa tcattattga ttttataaag tcactataaa ttttattaga ttattattat
     1141 aaaatcagag tgtggaaatg tttatgtgta ttctttaaat aaaaatttcc acattctgta
     1201 aggttattat acttgatata taaaattcaa tttaggaaca tagtctaaca tttataaaca
     1261 tattaaggta atgatttctc ttggtaatta ttctcatatc ttattctttg attatattta
     1321 tcttattcct agcccttatg tcatattata tttcttatct tattacttat aattagcatt
     1381 aacttatcta aaatcttgta tttttttaat agtaaagttt acatctatat taaaaagttt
     1441 acatctatat taatttcata aaacaatcaa ggtagtcaag agattcaact ttatttgatt
     1501 ttaaaaattt aagtgaattt gttcttatac acaccttttt aaaattatat ct
//
LOCUS       DAEQAF010000207         1527 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.212, whole genome shotgun sequence.
ACCESSION   DAEQAF010000207 DAEQAF010000000
VERSION     DAEQAF010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1527
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.212"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(386..1093)
                     /locus_tag="KRN00_003638"
     CDS             complement(386..1093)
                     /locus_tag="KRN00_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBH1829433.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     ENFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAMNDKKMME
                     IENGKYFNTISLIARTK"
BASE COUNT          494 a          257 c          135 g          641 t
ORIGIN      
        1 atttgattta aagtataata aaatatataa aaaaatatgt aaaatggtac tataaaattt
       61 ttaatcttca tcaatacctt ttttgctttc attgttaaaa ctattttttc tattagttta
      121 tttcttataa aacaaacatt tagtattaaa atatatatca cacaatagta tttgcaattt
      181 aactttaaaa aaataaaaat acccaactga cctaagcaac tcgattgggt ataaataatc
      241 taaaaaatca tttttgtata aactctttat ttaacttaca tttttattta ccttctactt
      301 taattcaact tatatttcta tgcttcttat actctcattc aacttatatt tctatgcttc
      361 ttatactttt ataaattcat cacaattatt tagttctcgc tatcaaagaa attgtattaa
      421 aatactttcc attctctatt tccatcattt ttttgtcatt catagcatat gaattatcac
      481 aatttatcca atccttccaa gcttcatcat gacaatttaa agcttcacat ttctctacaa
      541 tcacagactc cgattcagac caaagtttat tccaccatgt aattgaatgg aagttcatat
      601 tatcttgcca aaatggaatg agttcatctg gtatacaatc cacgaaatct tcttttaatc
      661 caggcattgc catagcaagt attcccccct cttttacaag aggtgatata tgattgtcta
      721 aaaatccttc tttgtttcca aaatagtgat aagaatcgat acttatcacc gcatcaaaga
      781 aattttctgc ataaggtagt tcatgtgcct ctgcctgtat tggaaatatt ttatcatcca
      841 atttaaactc tttaaatctt ttatagtttt cagttggttc tatccataaa tctgttgcaa
      901 atacagtagc atcaaattcc tttgctaaaa atatcgaaga tataccctta ccacaaccta
      961 agtctaaaat acgcattccc ttttctagtt ttatcttact tgttaattct tccaatattt
     1021 ttatacaatt aggtcccatc atatttttca tgagaaagtc cttatcgtat ttattacttt
     1081 ttgtaaatat cattctatct ttccttcccc tatcagttat tatttattaa attttatacg
     1141 tttgattttt tattttttat atgcttctta tattgagcaa tctctttttt attcattctt
     1201 taataggcaa ttttaatgtg taattttatc cactctgtga tagtaacttt aatgaataat
     1261 cttatctagt gtgatagtta ttttagtgag taattttatc tactccacag taatcgcttt
     1321 aatgagtaat cttatccact ctatgatagc tatttttatg gacaatttta tctactctat
     1381 aatatagtca ctttaatgag taatcataat ttttatatca ttttagatac ttactctaat
     1441 aagaagtcat tttctaatac ttaataagtt ttaattactt ccactttaac ctatatacta
     1501 attaacttat ttaatttagt gcatatt
//
LOCUS       DAEQAF010000208         1417 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.213, whole genome shotgun sequence.
ACCESSION   DAEQAF010000208 DAEQAF010000000
VERSION     DAEQAF010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1417
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.213"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            22..98
                     /locus_tag="KRN00_003639"
     tRNA            22..98
                     /locus_tag="KRN00_003639"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56..58,aa:Asp,seq:gtc)
     gene            108..182
                     /locus_tag="KRN00_003640"
     tRNA            108..182
                     /locus_tag="KRN00_003640"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:140..142,aa:Thr,seq:tgt)
     gene            197..281
                     /locus_tag="KRN00_003641"
     tRNA            197..281
                     /locus_tag="KRN00_003641"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:231..233,aa:Tyr,seq:gta)
     gene            291..374
                     /locus_tag="KRN00_003642"
     tRNA            291..374
                     /locus_tag="KRN00_003642"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:325..327,aa:Leu,seq:tag)
     gene            404..480
                     /locus_tag="KRN00_003643"
     tRNA            404..480
                     /locus_tag="KRN00_003643"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:438..440,aa:Arg,seq:tct)
     gene            488..563
                     /locus_tag="KRN00_003644"
     tRNA            488..563
                     /locus_tag="KRN00_003644"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Gln,seq:ttg)
     gene            651..739
                     /locus_tag="KRN00_003645"
     tRNA            651..739
                     /locus_tag="KRN00_003645"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:685..687,aa:Ser,seq:tga)
     gene            743..818
                     /locus_tag="KRN00_003646"
     tRNA            743..818
                     /locus_tag="KRN00_003646"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:776..778,aa:Phe,seq:gaa)
     gene            825..898
                     /locus_tag="KRN00_003647"
     tRNA            825..898
                     /locus_tag="KRN00_003647"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:859..861,aa:Met,seq:cat)
     gene            913..989
                     /locus_tag="KRN00_003648"
     tRNA            913..989
                     /locus_tag="KRN00_003648"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:947..949,aa:Ile,seq:cat)
     gene            1013..1089
                     /locus_tag="KRN00_003649"
     tRNA            1013..1089
                     /locus_tag="KRN00_003649"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1047..1049,aa:Pro,seq:tgg)
     gene            1097..1173
                     /locus_tag="KRN00_003650"
     tRNA            1097..1173
                     /locus_tag="KRN00_003650"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:His,seq:gtg)
     gene            1182..1257
                     /locus_tag="KRN00_003651"
     tRNA            1182..1257
                     /locus_tag="KRN00_003651"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1215..1217,aa:Lys,seq:ttt)
     gene            1265..1338
                     /locus_tag="KRN00_003652"
     tRNA            1265..1338
                     /locus_tag="KRN00_003652"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Cys,seq:gca)
     gene            1345..1416
                     /locus_tag="KRN00_003653"
     tRNA            1345..1416
                     /locus_tag="KRN00_003653"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1377..1379,aa:Asn,seq:gtt)
BASE COUNT          334 a          329 c          381 g          373 t
ORIGIN      
        1 cctgttggtc ccaccatttg cggcctggta gttcagttgg ttagaatgcc agcctgtcac
       61 gctggaggtc gagggttcga accccttcca ggtcgccaaa ataaaatgct ggtgtggctc
      121 aacggtagag cagctgactt gtaatcagca ggttgtaggt tcgattccta tcaccagctc
      181 catgtaaaat taatacggag gatttcccga gcggccaaag ggggcagact gtaaatctgt
      241 tgtcatcgac ttcggtggtt cgaatccacc atcctccacc aaaaaaatgc gcggatgtgg
      301 cggaattggc agacgcacta gacttaggat ctagcgccat tggcgtgggg gttcgactcc
      361 cttcatccgc accatttttg tttgatatac atatataaat tgtgggtgca tagctcagct
      421 ggatagagca acgcccttct aaggcgtgtg tccggggttc gaatccctgt gcgctcacca
      481 catatattgg ggattagcca agtcggtaag gcacatgact ttgactcatg tatgcgtagg
      541 ttcgagtcct gcatccccag ccaaatgatg tattactaag ctatatttga attattttat
      601 tttaaatata gttaggttca attttagaat aagtttaagt atccgaatgt ggagaggtgt
      661 ccgagtggtt taaggagctg gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg
      721 aatcccaccc tctccgccaa atgcccagat agctcagtcg gtagagcagg ggactgaaaa
      781 tccccgtgtc ggtggttcga ttccgcctct gggcaccaaa atatggcggt atagcttagt
      841 tggctagagc gttcggttca tacccgaaag gtcataggtt cgactcctat taccgctact
      901 aaaatttaat gtgggccatt agctcagttg gttagagcgc ccggctcata accggtaggt
      961 ctggggttcg agtccctgat ggcccaccac attaaattaa ttaatataaa ttcgaggtgt
     1021 agcgcagttt ggtagcgcac atggtttggg accatggggc cgggggttcg agtcccttca
     1081 cctcgaccaa tataaggtgg gtatagctca gttggttaga gcgccagatt gtggctctgg
     1141 aggtcgtgag ttcgactctc attatccacc ccaattcata tggtctatta gctcagtcgg
     1201 tagagcacct gacttttaat cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa
     1261 aggtggcgac atagccaagt ggtaaggcag tggactgcaa ctccttgatc cccagttcga
     1321 atctgggtgt cgcctccaaa atattccaag gtagctcaac ggtggagcaa ccggctgtta
     1381 accggtaggc tgtgggttcg agccccaccc ttggagc
//
LOCUS       DAEQAF010000209         1407 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.214, whole genome shotgun sequence.
ACCESSION   DAEQAF010000209 DAEQAF010000000
VERSION     DAEQAF010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1407
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.214"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(111..1151)
                     /locus_tag="KRN00_003654"
     CDS             complement(111..1151)
                     /locus_tag="KRN00_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1829434.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
BASE COUNT          446 a          255 c          139 g          567 t
ORIGIN      
        1 ggataataaa atgctattac acaaaaaaac acttagaaaa tagttttcca agtgtttttt
       61 atcaatttta taatttcaaa ttttagaatt gagaataaaa agcctaatta ttatacatct
      121 atttttctgt acaatgtagc tagtgatatt ccaagttttt tggcagctag ttttttagac
      181 ttagtatcat ttccgtaaaa ctttaacact ttctttatat aggctctttc aaactcttca
      241 agtgtaagta tgtcttgttc catacttatc tcatagtcac tttcctcaag taactttata
      301 tttatattat ttaacttaaa atattcaagt atctttctat ttattattcc tttatgtatt
      361 attccatctt cctcaagaag gtttaatgcc agttctatag tattttccaa ctctctaata
      421 tttcctggcc aaggatactt aagcaacatt tgttccacat ctggctctat atggtacacg
      481 tttttcttca tctttctcga atatttgtct ataaaattgt ttattaatat ttgtatatcg
      541 tctcctcttt ctctaagtgg aggcacttct aaaggtatta cattcaatct atagtataag
      601 tcttctctaa atttattttc cttaaccaac tcaaataaat ctctattagt agctgatatg
      661 attctaacat ctatatcaat tagttcattt gaacctattc tcgtaaactt cttttcctgt
      721 aataccctca ataactttga ttgtagttga attggcatat ctcctatctc atctaaaaat
      781 acaacccctc cattggccaa ttcaaactta ccaattttac cttttgaatc tgctccacta
      841 aaagctcctt ttgtatatcc aaaaagttca ctttctagta aaggttctgg tatagcagca
      901 cagtttatag caacgaatgt tttattccct ctgtttcctg cgagatgaat ggctcttgct
      961 attaattctt ttccagtgcc actttctcca gttatagcta cagtagaatc actatttcca
     1021 attttacaaa ttctattctt aagagcacgc attacatcag actctccaat tatggagtct
     1081 actgttgttg ttccccaaat attatatact tccattccac catacattac tgaatcactg
     1141 tgtttgtcca taaaatatca actccaaata agtattctat ataataatca ttcacattat
     1201 ctatttaatt atatcataac agaaaagctt agttataatt taataatatt attttaaaac
     1261 aaaacttaat aaaaagtata tctacttagt tttaatttga tagatatact ttcttcattt
     1321 tacaaaaatc ctctattaaa taagcaatta caatgccata ttttatatgg aaataatttt
     1381 taaaattttt aatttaagtt cttatta
//
LOCUS       DAEQAF010000210         1403 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.215, whole genome shotgun sequence.
ACCESSION   DAEQAF010000210 DAEQAF010000000
VERSION     DAEQAF010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1403
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.215"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            30..1310
                     /locus_tag="KRN00_003655"
     CDS             30..1310
                     /locus_tag="KRN00_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBH1829435.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSSISFSLDDTIFKTLISY
                     DIKATNIYNLIYYKNNKDLVKGPMDFYTHPIYVK"
BASE COUNT          597 a          179 c          163 g          464 t
ORIGIN      
        1 aaaataatta aagataaaag gagtatttta tgaacatact tggattaata gttgaatata
       61 acccatttca taatggacac atatatcatt tatctaaatc tatagaaaaa acaaatgcaa
      121 cacatactgt agcaataatg agtggaaatt ttctacaaag aggcgaacca gctttatttg
      181 ataaatacac tagagcaaaa attgctgtcg aaaatggtgt agacttagtt atagaattac
      241 caactttatt tgcttgtcaa agtgctgaaa ttttttctca tggtgctata acaattttaa
      301 attcactaaa ctgcataaat tctatatgtt ttggtagtga agaaggaaat acagaaattc
      361 tttataatat agctgaaatt ttagcaaatg aaccaaatga atttaagtta cttttaaaaa
      421 aatatttaga tgatggtctg ttatttccaa cagctagagc taatgcactt tttgattata
      481 tacatcaaga caaaaaaaat aattttatac aaaattattc aaaggaacaa ttatcaaaaa
      541 cattaaattc atcaaacaac atactgggta tagaatacat aaaaaacctc atccatttaa
      601 acagtagtat aaaaccattt actatatcca gggtccaatc agaatataat tccgaagaaa
      661 ttgagagtga tatttgttct gctactgcta taagaacttc acttaaagaa aatacagacc
      721 tttttcattt aaaaaatgtt attccagaaa aaacttataa catcctaaat gaaaaaatag
      781 ataatggttt tttacctatg tttgatgact tcttctttga tattttaaaa acaattatac
      841 ttagagatat ggacacttta aaagagtatt ttgaagtaaa tgaaggcata gaaaacagaa
      901 tctataaaga tatctttaca tctgaatttc tacatgaact acaattagca attaaatcca
      961 agcgatacac tttaaccaaa atcaaacgaa ctctaaacaa tatattgcta ggtattaaaa
     1021 aaagcgacat gcaacttata aaaaacatag atactatacc ttatataaga atacttgctt
     1081 ttaatgataa aggtagagaa attctaaaag agataaaaaa taaatctgaa ataaaaataa
     1141 taaacaagtt ttcaagtata tcattttcat tagatgatac gatttttaaa acactcataa
     1201 gttatgatat aaaagctaca aatatatata atttaatata ttataaaaac aataaagatt
     1261 tagtaaaagg ccctatggat ttttatactc atccaatata tgtaaagtag ttttttaaaa
     1321 taactatatt tataaaaatc attttattaa ctctttatta tataagatac aatagtctta
     1381 ctttatttat gtacacatgc ttt
//
LOCUS       DAEQAF010000211         1336 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.216, whole genome shotgun sequence.
ACCESSION   DAEQAF010000211 DAEQAF010000000
VERSION     DAEQAF010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.216"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(302..1183)
                     /locus_tag="KRN00_003656"
     CDS             complement(302..1183)
                     /locus_tag="KRN00_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBH1829436.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEVDQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNAND"
BASE COUNT          456 a          246 c          138 g          496 t
ORIGIN      
        1 ttataattaa tatacttttt aatcaaattt aaacagaata attataccaa tatataaaaa
       61 aatttctaaa aaacaataaa attaagttat aaacaccaat atatttctat tatttcaata
      121 agtatacaat tagattagaa tctaacgcta gtaataaaaa attactttcc caaaatagat
      181 ataagcttca ttttatcgtt caaataatga aaatatattt gatttcatgc aaaaagagtg
      241 cctaatgaac taaaaagttc attttgagac actcattttt ttatataaat ttatatagtt
      301 tttaatcgtt cgcattcaac cactcagtta agacttttat atatttctca ttttcttcaa
      361 cgaatggcat atgtcttgaa tactcaaata attcccactt actattaggt attctatcat
      421 acatagtctt tgcaatatat ggtgaacata aatctattgc tccactagtt actagacaag
      481 gctcttttat ttcatgtaat ctatctgtaa attcatatcc agaaagagtt cctgtaggag
      541 aaaattcatt ttgtccccat cctacaatat atgcttcaga acctgatttt ttaggtcttc
      601 tcaggcactc tggagaatct tctgtcactt cacctgcaca atacatttcc ataaatcttt
      661 ctaatgcatc attatattct ttgctagagt aatctccagt atttactgca tcaagtaatg
      721 ctttttggtc aacctcactc atatatgata ttcttctttt ttgttctttc tcccaaagtt
      781 ttgcagaaga aagagtagat gaaaggatgt aagacttaat accttttggt ttatattcaa
      841 tagcatacca aatagcctgc atacctcccc aagattgacc taacagatga atttcatcaa
      901 gtcctagatg ttttcttagt tcaataagct cctctatcca agtatctgca ttaaatagct
      961 caggatgccc ttctacaaat gaatttccac aaccaatttg gtcatacatt attacttgtc
     1021 taccactttc agctatctta tccaatacct caaaatagtt gtgtgtagaa cctggacctc
     1081 catgaagtaa tactaatggc ttcttccctt ccgtattttc tcctactata cggtaatacg
     1141 ttttaaaacc tttaaaaggc atatatcctt cagtaatttt catgtttatc tcctccaatt
     1201 tgtaattata aacaataatc aagttcatta acaatactat ttaaaacctc ttatacatat
     1261 ttgattatgt attttaatct ttatacctac ttttataaat agtataacat aaaagttaaa
     1321 aatctctata ctaaac
//
LOCUS       DAEQAF010000212         1192 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.220, whole genome shotgun sequence.
ACCESSION   DAEQAF010000212 DAEQAF010000000
VERSION     DAEQAF010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1192
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.220"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            6..473
                     /locus_tag="KRN00_003657"
     CDS             6..473
                     /locus_tag="KRN00_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH1829437.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGCCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMVISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            484..699
                     /locus_tag="KRN00_003658"
     CDS             484..699
                     /locus_tag="KRN00_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829438.1"
                     /translation="MAIVVNLDVMMAKRKISLKELAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
BASE COUNT          432 a          139 c          151 g          470 t
ORIGIN      
        1 attttatgat tacaaaattt tttagtaata tattatcagt atttctatat tttctattat
       61 cacttttagg agttgctggt ataatattct tatgtatgat acctatgttt ttatatgatt
      121 ttagttctga caaagtaatc gctttaattg caagaatact atatttttct gactacttta
      181 tagtcatctt attcttgata tttataatta atagtactaa gtattcccca ttcgtacttg
      241 aaaatgtaaa aaggtttaag gtaatgggat gttgtttatt gataaacact ataattgaat
      301 gtatcaatgg ttataattta aatactaata atataagaat ttttggaact gatagtggcg
      361 gtatctcacc acttatggtt atctctttta tatttgcact aatgtgcttt gtaattgcag
      421 aaacatttga taaagctata aaaataaaag aagataatga tttaacgata tagaggtgat
      481 gttatggcaa tagtagttaa cctagatgta atgatggcaa aaagaaaaat atcacttaaa
      541 gaattggcag aaaaaataga tattacaaat gcaaatttat caattttaaa aactggaaaa
      601 gcaaaagcta ttagatttac cactctaaac gaaatttgca aagctttaga ctgtcagcca
      661 ggtgatatac ttgaatatgt agaagatgaa aatgattaaa aaagagtgtt tagaaacact
      721 cttttttatt atactatatg atttttattc ttttactata ttattgacat taatattaac
      781 tttgtttaaa gtcataacaa aatatgttct aagaaagaaa ctgttccttt atctatttgt
      841 tatccattac ctataagaac tgtatcatac taaataatac ttttaaattg ataattttac
      901 cacagattcc tatatacatt cttttctacc taatatttat ttaaactgtt agcaaaacat
      961 ggaacttttt catttactta tacccccatt tatattattg catagtttat agctacgtgt
     1021 tataaattac attattgatg attttatcta acatttgtaa tcttttagat actctttgaa
     1081 gttacaacac tgttatactc taattaagta aactaaatct gatacaagtt ggtgattata
     1141 tgaaaagaaa actttcaacc tattttaaag gatatatttt aggtttatgt at
//
LOCUS       DAEQAF010000213         1183 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.221, whole genome shotgun sequence.
ACCESSION   DAEQAF010000213 DAEQAF010000000
VERSION     DAEQAF010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1183
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.221"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            7..264
                     /locus_tag="KRN00_003659"
     CDS             7..264
                     /locus_tag="KRN00_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829439.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(374..1054)
                     /locus_tag="KRN00_003660"
     CDS             complement(374..1054)
                     /locus_tag="KRN00_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBH1829440.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYLIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISEKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
BASE COUNT          483 a          148 c          128 g          424 t
ORIGIN      
        1 attgatatga taataattag aagtcaagat aaaactaatt taatgcagat aaaccaaatt
       61 aaaatagatg gtagtcaagt ttatgcagta tttgaaagta aaattgatac tgtaaaaata
      121 ggagattatg aaaataatac aagagctata caagtgttgg acaatataca aaacttcatt
      181 gaaaatggaa caaaatatga ttatataaca tcaaataaag tcagatacaa tgttaataaa
      241 atatttcaga tgccagctaa atagtgagtg tgcattttaa tttaataact aaagcccact
      301 ttcttttgta gtatgaaaga gggctttaca tatttgtaaa tatcgaagta cacttgtttt
      361 atcaataaat tatttaataa ggtataatgg accaattaaa caataaaaat tctcctaaaa
      421 cagcaagtat taaatatata atagcttcat ttttgtaaag agaggtaatt ttttcgctta
      481 tgtcatcatc aattgtaata gcaatttcat cttgaataat atttttatat atagatggga
      541 aaatatcttt tttctttata agattaaata aattatttac acctacccat atcaaatatc
      601 ctaaaacagc acctaatgtg ttcatcatta aatcatcaat atctgtagct cttaagttaa
      661 acaattgaca aagttcaatt gctaatgaaa aacctaatcc agttaatgaa acattgataa
      721 tatttctaaa atttttccaa attaaaggta gtaaaaatcc taaaggcata aacataatta
      781 tatttaaaat atatgttaag atgccaactg agtcaaaagg tattagattt atttcatcaa
      841 ttctaaaaag cccactatac cttcctatat cccatatgct accaattcca gctttactaa
      901 gtgctagata gatatataat aaaaaaatat atacccatac taaatgtatc attacattct
      961 tttcaacttt caaatttttt cgttttataa cgactatttg gtatattaag catggtaata
     1021 taacgcaaat aaatgaataa aatgtccata tcattttatt ttgtcccctt tcaaatttat
     1081 gtttttagtt ttataagtac tatctttata ttaaactgta agttttaaaa atcttttaat
     1141 aaaatcttaa aaatttatta atttataaaa atatattatt aag
//
LOCUS       DAEQAF010000214         1128 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.223, whole genome shotgun sequence.
ACCESSION   DAEQAF010000214 DAEQAF010000000
VERSION     DAEQAF010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.223"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            71..940
                     /locus_tag="KRN00_003661"
     CDS             71..940
                     /locus_tag="KRN00_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBH1829441.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITPEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
BASE COUNT          427 a          107 c          175 g          419 t
ORIGIN      
        1 ttaaacgtat aaagtttatt atcggaaatt tctatattaa tatgtagtaa ttcaatatta
       61 ttataaagga gtggttatta ttaaggcaat tgaactttat aaaaaattag atttagaatt
      121 taatattaaa aatattaatg atgattggag ttttatgaat tttgaaaatg attttattac
      181 tccagaattt agaaaaaaat acataggatt agtattagat aatgctcaaa atattaataa
      241 agtatacaca actacttttc ctgataaaga aataattaag caagttatag ataaagatga
      301 aaaagatatt ttaatttttt cacatcatgc aatgggatac atagcatcag atgaaggttt
      361 tccatttcac gacataccac tatcttatat ggaagagatg aaaaatcgta gaatttcttt
      421 ttatgtatta cattctccac tagacaacta tagtgactat tcaacttctg ttagttttgc
      481 aaaagctatg ggtttagaaa tagtcaaacc attttgtaaa tatgacgata aaattgaggt
      541 aggagttata tgtaaaacat cactaaaatc aatagaagag attaaggaat taattaaaaa
      601 atctgttggt catgatgtga aattgtatga ttatggagat tctgtattaa aagatggttt
      661 agttgctatt gcagcagggg gaggaagtta tccatttgta gcaagagaag ttgctgaact
      721 tggtataaat ctatatatta ctgggtttac taagccttta aaacattttg aaccagtatt
      781 agagttccat caaatagcaa aagataattt aattaatgtt ataggtgcta ctcattattc
      841 tacagaaaaa tttgcgtgta tgggcatggt tgattatttt aaaaatctag gtttagaatc
      901 agaatttttg caaggaaagt attacttaga ggatttatag gacatattaa acaaaaaaaa
      961 taaacagtta gtaaaaattt attttactaa ctgtttattt ttttacctat ttatctagtg
     1021 ttttgaaaaa atctatcttt attttttaaa ctaagaaaat agacttttaa ttgctgatta
     1081 gaagatttag ttttgatgtc ttttaaatta tttttcgata ttttttag
//
LOCUS       DAEQAF010000215         1126 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.224, whole genome shotgun sequence.
ACCESSION   DAEQAF010000215 DAEQAF010000000
VERSION     DAEQAF010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1126
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.224"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(297..803)
                     /locus_tag="KRN00_003662"
     CDS             complement(297..803)
                     /locus_tag="KRN00_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBH1829442.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTIAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHGNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
BASE COUNT          402 a          162 c          104 g          458 t
ORIGIN      
        1 atattaaaat aaatcaagta caaatgccat aaattaagtg tttctagtta gcataaaaat
       61 acttataaag tatactcaag tatttcaaat aaatactttt attcaaataa atctctactt
      121 atataagtgc ttatataaat aaaaagatga actatagtaa atatagttca tcttttttat
      181 aatagtattt atttaaaatt aatatttatt tagttactag catctactta gatatcagat
      241 aagaaagcac agtcatttac ttataataag ttcttttcat atatttttta ttataattat
      301 tcttttacaa gaacttttat aatttctgaa atgtacatag tatggtagtc tttctctgga
      361 taccattttt tatcattttc tttagcatca aagttttctg gtggcatatt accatgatat
      421 agctttttac atactataat catattagct tcttcaaaag ctaccgtatc atccacaaaa
      481 tatggtgtaa gtcctgcttt ttctatttta tttatatctc taccagaaat agtgccacaa
      541 atatttaaag cttctctata cgtttcatca aagaaggcaa ttgtaaatgt atcattacta
      601 tctacaaatt cttttgtata tctctgtggt cttatgtaag ttgtaacaac atttttaccc
      661 caatagactc caacaccacc ccagctagca gtcattgtgt taaacttttc tgaatcacca
      721 gctgttataa gtaaccattc tttgccaatc ttagtaaatg gattaaactg taattcctca
      781 atttttactt ctctaaaacc catgacttca tcctaccctt cattttttaa ttatataaat
      841 taattgttaa aaatttgaat atatgtactc ttataatact gacttttgat tgtcctacat
      901 aattcatgta aattataata caacaaatca attactttcg caataagtag ttttcatatt
      961 ttataagtgt aaaatataga taaaatatat tgattataaa gtatataata tatttttaaa
     1021 cctaaagcaa tatacaataa aaaaatgtag aaagtaagta tctctctaca ttttttattg
     1081 tatattattt ttatattaat ttaattttat cttgattcag ttttat
//
LOCUS       DAEQAF010000216         1074 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.225, whole genome shotgun sequence.
ACCESSION   DAEQAF010000216 DAEQAF010000000
VERSION     DAEQAF010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.225"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            210..350
                     /locus_tag="KRN00_003663"
     CDS             210..350
                     /locus_tag="KRN00_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829443.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(347..718)
                     /locus_tag="KRN00_003664"
     CDS             complement(347..718)
                     /locus_tag="KRN00_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829444.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
BASE COUNT          406 a          108 c          132 g          428 t
ORIGIN      
        1 taatagattt ttttgttatt attacgagtt ttttattgca actgtagaat aaaagtatta
       61 ttatataatt aagataatta tctagggaaa ttttggataa tcaaaatata ttttataaaa
      121 tcaaaatgca attacataaa ctttattaaa aatttgttgg gaatttctga ctaacattaa
      181 gaacgtaagt ttgttggggg atggtatatg tggaaaagtc aaacactact gttacaaaaa
      241 aagaaaaaat tgaagatata ggaatgaaat tagaacattt attgagtgaa gatattactt
      301 tttatgaatt attacttgag attttgtata aagaaaaaga agagaattaa ttctcttctt
      361 taaggaatct ttttaaatag gcattatcaa tcattttttc tatagcttct ctatcttctt
      421 tttcaagaga atatattttt tctaagagct tttttgtttt ttcacttact gataagttct
      481 ctatgattaa tttatcttct ttgcttattt ttgtattatc atttacgcct aataaataat
      541 ctgttgatgt ttctaatgct tttgctaatc taactattat ttcactttta ggttctctta
      601 aattattttc ataacgtgac aagctagcct cagttatacc gactttagta gcaagttctt
      661 tttgatttat atctaattct tttcgtagat ttgctattct atctcctaaa ctttccatat
      721 gtacatcact ccttaccgaa attataagtt attttgataa aaagtaaaat aaaattacca
      781 aaaatataaa aaaaaaaggt taaaataata aaatatattg aaaattacca tttgtatatg
      841 tataatatga attatacaaa tggtaatttg atgagaggtg gtatgttgaa ataagaaact
      901 gaattaatta ataaatacat agaaagtttt gaaaaccttt aattgaaata taaacaatat
      961 gtacaaaatt ttttgcaagt aaaattacca aatgtataaa ataaatcagt agcatagata
     1021 attttatgct ttaatacatt agattattta atttagttat aatggtcaaa aatg
//
LOCUS       DAEQAF010000217         1048 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.226, whole genome shotgun sequence.
ACCESSION   DAEQAF010000217 DAEQAF010000000
VERSION     DAEQAF010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1048
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.226"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            225..905
                     /locus_tag="KRN00_003665"
     CDS             225..905
                     /locus_tag="KRN00_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBH1829445.1"
                     /translation="MQIDVLIIDGDKNSSQELKNFLEGKGINVYLAYNCKDAIIKIFS
                     KKFDLIFLEIILVDGDGWDFCKKVRSITTCPIIHITYINENQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRRDLFLNNNKNNIKLEDYNRASGVIKLENKMIKLTPTENRLL
                     NYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVVVAVSGLRKKIEKDYKNPQKIITIRE
                     VGYYFNKI"
BASE COUNT          457 a           65 c          172 g          354 t
ORIGIN      
        1 ataccaaata aagtgtatat cttaaaacaa tttactagag atacaaggat gctatgtgaa
       61 ttttgaagtg tgcagtttag ataataaata tatataaata ataaagaaaa tggatttata
      121 gtatttaaaa tttcttataa gggtaaaaaa tgctattaga aaatgtacta aaaatatttt
      181 tccaattctt tatagaaaaa taatgatatt taggagagat tgtaatgcaa attgatgtat
      241 tgataattga tggagataag aatagttctc aagagctgaa aaatttttta gaaggaaagg
      301 ggataaatgt ctatttagca tataattgta aagatgctat tataaaaata tttagcaaga
      361 aatttgactt aatattttta gagataattt tagttgatgg tgatggttgg gatttttgta
      421 aaaaagttag aagtataact acttgcccaa ttattcatat aacttatata aatgaaaatc
      481 aaagtatttt aaatgcttta aattctggag gagatgatta tttaataaag cctttaaatt
      541 tagaaatatt atatgcgaaa gtgaaagcta ttttaagaag aagagattta tttttaaata
      601 ataataaaaa taatataaaa ctagaagatt ataatagagc tagtggagta ataaagttag
      661 aaaataaaat gataaagtta actccaacag aaaatagatt attaaattac tttatagaga
      721 atgctgaaaa gactctaact attaaggaga tatatgaaca tgtatggatg aatgagtatt
      781 tagatgataa ttatagtgta gtggttgctg tgagtggatt aagaaagaaa atagagaaag
      841 attataaaaa tcctcaaaaa attataacga taagagaagt agggtattac tttaacaaga
      901 tataaagctt tataaacaga atgaatgata aggcatagat aatatgttag tatattacaa
      961 gagtttttgt tctaacgata tatttgtaaa attagattta atttacttaa ttaaattata
     1021 gcagtagaat aaatataaaa aatgtctg
//
LOCUS       DAEQAF010000218          949 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.227, whole genome shotgun sequence.
ACCESSION   DAEQAF010000218 DAEQAF010000000
VERSION     DAEQAF010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..949
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.227"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            96..659
                     /locus_tag="KRN00_003666"
     CDS             96..659
                     /locus_tag="KRN00_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829446.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
BASE COUNT          384 a           93 c          140 g          332 t
ORIGIN      
        1 aaaatttgta aaaccacatt tattatgtta gaatatctta tgatattaaa ttgtaagtgt
       61 ataatattat ttagttacta gattgggggg aaatgatgaa taaagtctat attgtaacaa
      121 catatacagg aactatatta tcttacttaa taaggaatat aagtaaaaag ctgtatacac
      181 atgtgtcaat atcattaaat gaaaatctaa aaccaatgta ttcttttgga aggctaaatc
      241 caaggaatcc atttattgga ggatttgttg aagaaaatat aaatcaagga ttatatgcta
      301 taagaaaaaa cactgtgtgt agggtatatt cgttagaagt agataattta caatatgaaa
      361 atctatataa aaatataaaa ttaattagtg attatagaga agattactat tacgatacaa
      421 tggcattaat atatttacta atgaatattc agagacaatc tgaatataaa tatgtatgtt
      481 caaattttgt tgctgacatg ttagaaaaaa gtgagataga cattttaaat aaacaagcat
      541 ttgaagtaac gccaaatgat ttttataatt tatctggctt aaccttagag tatgaaggtt
      601 tattatcaga atataattct agacaacatt cttatgtatc aaaaatcgca aacatttaaa
      661 aacttgattt agagtttttc atataaaaaa atattgctag ataattaggc tgaagatagt
      721 agtttaactt cgataggatt aagaatttgt aaatcttagt tagaatactt tcttcagttt
      781 ttaaatttct gctaatattt gtatttttat aacatttttg gatatatata atacagaata
      841 gtgcaaaaat cccactcctt taggtgcggg atggatagca caaacagtgt ataaaaagta
      901 tttatacata cacgtataat attaaatata gttgaataag cagaactat
//
LOCUS       DAEQAF010000219          920 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.229, whole genome shotgun sequence.
ACCESSION   DAEQAF010000219 DAEQAF010000000
VERSION     DAEQAF010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..920
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.229"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            217..876
                     /gene="cprR"
                     /locus_tag="KRN00_003667"
     CDS             217..876
                     /gene="cprR"
                     /locus_tag="KRN00_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBH1829447.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
BASE COUNT          374 a           55 c          175 g          316 t
ORIGIN      
        1 attgttaaat aaatttttat atttaagtaa atacgtgtaa aatgaatata aagtttttga
       61 aatataaagt ttttgtatct aaaatatttt atttgtaaaa tagtaattaa ttattgtaag
      121 ctataatatg agagtattat ggttaatgtg aattttaaag atattattaa atatataaat
      181 tagaatgcta ttagatggat aaatggagga gttattatgt ctaagatatt agtagtagat
      241 gatgagttag atatgttaaa gttgattgaa aatgtgttga aaagagatgg acatgaagta
      301 aaggtaatta gtgatgtaga aaaggctatg aacatggatt ttaattattt taatctaata
      361 atattagatg ttatgatgcc taagatggat ggttttgaag tatgtaaaac tataagaaat
      421 aaggttgatt gtccaatact gtttttgaca gcaaaaaata tggaaagtga tattatgtac
      481 ggtcttggta taggtgcaga tgactatata accaaacctt ttggtgtagg agaattaagg
      541 gctaggataa ctgctcattt aaggcgagaa agtagagaaa aaaagaattt attaactatc
      601 tcaaatgttc aatttaactt tttaggcaaa gaagtttcaa ttgatggtaa aaaaattaat
      661 tttactaaaa gtgaatatct aatatgtgaa tttctagcaa aaaataaggg acaagtattt
      721 tcaaaagaaa gaatatatga gtcggtatat ggttttgatg gagaaagtga tataagtact
      781 atcacagagc atataaaaaa tatacgaagc aaattaaaac aatatgatat ttatacaata
      841 gaaactgtat gggggatagg gtataaatgg gtgtaataag tataagtgtt gtttagtgaa
      901 aatattatat atatctacaa
//
LOCUS       DAEQAF010000220          882 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.230, whole genome shotgun sequence.
ACCESSION   DAEQAF010000220 DAEQAF010000000
VERSION     DAEQAF010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.230"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..798
                     /locus_tag="KRN00_003668"
     CDS             <1..798
                     /locus_tag="KRN00_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBH1829448.1"
                     /translation="KYNNNKLIYSNMIDKKTQNSVKEILKENKINEKDIDTFIKAVNN
                     YNKLQVKILQNNINISKSGYSSINAKQVPYNLEKLQDNWVKKFPDYMDVNCRITAFRL
                     FKDFINSNKKFTGDSIDLNVDLDTIMNNKDAKFSTKDVEKFINFFSAIPAKDTDDTIK
                     IAEQIKNEWKKRKISFKNNKNISIINGFLRYPETKNVFIGHTGICIKTKNGILFLEKY
                     GVTSPYQVTKFKNKEDVKNYMFNRLKMSEGEIELPDPIIMENDKLMK"
BASE COUNT          409 a           94 c          108 g          271 t
ORIGIN      
        1 aaatataata ataataaatt gatatattct aatatgatag ataaaaaaac tcaaaatagt
       61 gtaaaggaaa tcctaaaaga aaataaaatt aatgaaaaag acatagatac atttattaaa
      121 gcagtcaaca attataataa attgcaagtt aaaatacttc aaaataatat aaatatatct
      181 aaatctggat attcttcaat caatgcaaaa caagttccat ataacctaga aaaattgcaa
      241 gataattggg tgaaaaaatt ccctgattat atggatgtaa attgtagaat aactgctttt
      301 agacttttta aagattttat aaattcaaat aagaaattta ctggagactc tattgacttg
      361 aatgtcgact tggacactat aatgaataat aaagatgcta aatttagcac caaagatgta
      421 gaaaaattta ttaacttctt ttctgcaata ccagctaaag acacagatga tacaatcaaa
      481 attgcagaac aaataaaaaa tgaatggaaa aaaagaaaaa tatcttttaa aaataataaa
      541 aatatatcta ttataaatgg atttcttcgt tatccagaaa ctaaaaacgt atttataggt
      601 catacaggca tatgtattaa aactaaaaat ggcattctat ttttagaaaa atacggtgtt
      661 acatcacctt atcaagttac taaatttaaa aataaagaag atgtaaaaaa ttatatgttt
      721 aatagattga agatgtcaga aggtgaaatt gaattacctg accctataat aatggaaaac
      781 gataaactta tgaaataata actttaaacg caaaataata tttataatta ctaagtcaat
      841 ataatagaga aggtctatag atttgtgtaa atacaagctt at
//
LOCUS       DAEQAF010000221          876 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.231, whole genome shotgun sequence.
ACCESSION   DAEQAF010000221 DAEQAF010000000
VERSION     DAEQAF010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.231"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            110..652
                     /locus_tag="KRN00_003669"
     CDS             110..652
                     /locus_tag="KRN00_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBH1829449.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
BASE COUNT          362 a           74 c          148 g          292 t
ORIGIN      
        1 atcacggaga acttttacct tcttcaatta atatattatt attagtaata actttaaaat
       61 tatattacta ttatataaaa attggcttaa aagaaggtga aaaaagtaaa tgaaaatatg
      121 cataacagta ggtcatagta tactaaaagg tggtaaaagt acaggtgtaa atggtatagt
      181 tgatgaatac aattataata aaaaattagc tcctatgtta gctgagatgc ttataagtca
      241 aggtaataca gtagatgtaa taatttgtcc agaaaggcac tttatgtcag aaagagaaga
      301 atttttctat agagttccaa aagtaaacag tggtaaatac gatttattag tagagctaca
      361 tttaaataaa gctgatggaa cacaatgtgg tacagaagtg ctttactatg gcactgaagg
      421 attagaatat gctaaaagag tatctaatag acttggagaa ttatttgaaa atagaggagc
      481 taaaaaaaga gaaaatttat atatattgag aaatacaaat ccagttgcaa tacagattga
      541 aagttttttc tgtgataatg tgaatgattg taacaaagca aatgaatcag gttatgatta
      601 tatagcacga ttgattacag aaggtatatt gaataaagat ataaatatgt gagattatgg
      661 tgatttaggt attgattaat accttttaat attagatata aataaaaata caatgtatta
      721 gtataattta aactttcaaa agatagatta gtttgattat tgacaagaga tacctccttg
      781 aaaatattga tttatcagta tatttaagga ggtatttaaa tataaaaatt taattaattt
      841 gctactaaac tataggttta tagagtatat actttt
//
LOCUS       DAEQAF010000222          854 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.232, whole genome shotgun sequence.
ACCESSION   DAEQAF010000222 DAEQAF010000000
VERSION     DAEQAF010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..854
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.232"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(172..639)
                     /locus_tag="KRN00_003670"
     CDS             complement(172..639)
                     /locus_tag="KRN00_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1829450.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDILGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSIDEVAKRMDVTVEYIESVLE"
BASE COUNT          329 a          150 c           55 g          320 t
ORIGIN      
        1 tttaaacttt agtataaata tataagaaat atcataatat ttttaaaaac tcaaataaag
       61 ctaaacaagt attatattct ttattttaga aaaataaaaa ctgtaagcaa atttgttttc
      121 acacaagttt acttacagcc ttcacctcaa ttttacttta atataatcca tctattctaa
      181 aactgattca atatattcga cagttacatc cattctttta gctacctcat ctattgaaag
      241 accactatct aaaaaacgtc tacacacaga tgacatagtt tctccaacct caataatatg
      301 cccatctaaa tcataaaatc taattgctct ttgaccccac ctatgctcta tagctagatg
      361 aacataatct atatctttca ttgtactcaa tctttcaaca aaagtatcaa aattatcttc
      421 ctcaaaatat aactcagcat catttccatt gaacttaact tcactgtcac tcttattaat
      481 aaattctaac caaagctttt tttcttgtaa tgatatatta ccttctaata caacattttc
      541 tccaaaatca cagattacct ttaaccccaa aatatcataa taaaactttt ttgatttctc
      601 aatatcttca actactatta aaacatttaa aaacttcata ttacctcctt aatatacaca
      661 tactttattt ataatatata attagaatta aactataaag gtttcaataa ggtctagtat
      721 aaagaaaaaa attataagtc ttattgaaat agttaagtta attttatcat ataatataaa
      781 ttttaatctt gtaaaaaaca gacatgttca tacttttagg tttaaatcta tatgtattct
      841 tattaatttt gcta
//
LOCUS       DAEQAF010000223          729 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.239, whole genome shotgun sequence.
ACCESSION   DAEQAF010000223 DAEQAF010000000
VERSION     DAEQAF010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..729
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.239"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
BASE COUNT          276 a           72 c           75 g          306 t
ORIGIN      
        1 actaaaacta agagttttga aataatttaa aataacaaaa aattttgaat taaaacaatt
       61 atttaattta ttataccata taatttaagt tattatgttg atttaaaacc tatttacact
      121 aattatctaa atatctcttt atttttataa tcttttatga cttatttata tttttcattt
      181 ttataaaaaa acaataatta agaatataac tatattctac atgtaaaaat ttttttattt
      241 aaactcaatt ttctgataat ttgataattt ttcaaaattt atagttgact tttatttttt
      301 actgtattaa actaattact atacaaaaca gaaaacaaaa ttttcaaaat tattaaatta
      361 aaaggagagg taaatatgaa gactttatta aacaaacaag tacgattttt tagtagccaa
      421 tttagttagg gtttgtacct aagttaagac aaattgtcat aacatagata caagcccctt
      481 aggattatga tttttaagga ttgtatctat gttggctata gtaattgttg ttaaagtttt
      541 tattttatca tcataatata gagccacatg gattatactg tgtggcttat tcgaattttt
      601 gccatacagt tatatatact gtgtggtttt tttatatcaa aatcattttt taaaaccaaa
      661 ttttaaaaac catttaaaat attttcaaag gggtgtttta tttatgtcag gtattatatc
      721 tgtaatgac
//
LOCUS       DAEQAF010000224          702 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.242, whole genome shotgun sequence.
ACCESSION   DAEQAF010000224 DAEQAF010000000
VERSION     DAEQAF010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.242"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            225..509
                     /locus_tag="KRN00_003671"
     CDS             225..509
                     /locus_tag="KRN00_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829451.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
BASE COUNT          296 a           46 c          101 g          259 t
ORIGIN      
        1 aaagatagta gctattttta tatagctatt atttttttat tgttgtggat gaaaatatac
       61 ttatatttta ctaatataca tttaaaaatt acaatttaaa gcattaaaaa ataaatttgt
      121 attttgtttt atataaagta atttgaaaaa tatggaaaaa ttgattagta cattattaat
      181 tagggtataa aatggtgtaa atagaatgat aaggggtgga tgaaatgctt gtatataata
      241 aaagttttta tcctaatgac atatttccaa gattagattt ttcaaaaata aaaaaacagt
      301 taaaattgat agataatgac ctgtcagatt ttggaagcat atgtataata gaaaaagaac
      361 attatacgat aagtgtaaac agtataggtg aaataaatgt gtactatgat ttagagtacg
      421 aaaataaggt gtatagaata gtttatgaga ttgaaaagtt atttaaatct caagttggaa
      481 ggtttagcat atctacatac agaaattgat aattaaaaaa gtagaaatta aaaaacttaa
      541 tactaaagat atagataaat atatgaggta acagctagag agagttgtta ccctttttaa
      601 atactaagta tatattattc ttattaattt tttgtaaatt cactaaaaga cctttttata
      661 gaatattatt ttcttttttt attaaatagg taaatcagta aa
//
LOCUS       DAEQAF010000225          663 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.247, whole genome shotgun sequence.
ACCESSION   DAEQAF010000225 DAEQAF010000000
VERSION     DAEQAF010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.247"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..608)
                     /locus_tag="KRN00_003672"
     CDS             complement(<1..608)
                     /locus_tag="KRN00_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829452.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDL"
BASE COUNT          211 a          117 c           35 g          300 t
ORIGIN      
        1 tttaaatctt taaaatctaa acttttacat tgttcatcat cttcccatat tcctgcttgt
       61 ttatttccat catttttata taatacacct ttaccatttt tcttattatc taaaaaatat
      121 cccttataaa tgtcattatt gggatatgtt aattttccca aaccattttt taatccgtat
      181 ttaaattcac ctgtatatat tgaaccatct ctataagtat attttcctat tccatgcatc
      241 ttgtcatctt tccataatcc ttcatacttt tccttacttg aaaaaatata tattccaaat
      301 ccatttttct ttccatcaac aaactcacct ttatataaat caccattatc gtatttaaat
      361 actttttctt cctttaattt cttattgtta ctcttatttt tattattatt gttatccttt
      421 atatgtattt cttctcttct ggcttcaata aaatctctat catacctaaa tccgtttctt
      481 gatttaattt tttgattaat cttcttctta ttaataaata ctctagctag ttgagtaaat
      541 ataaatacag atgataagca tataaataca catagtattg ttgtaaaata actagttata
      601 ttttccataa aaaatcaccc tttaaaaaat ttatttaaaa tacctaatat aatatatatt
      661 ttt
//
LOCUS       DAEQAF010000226          651 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.249, whole genome shotgun sequence.
ACCESSION   DAEQAF010000226 DAEQAF010000000
VERSION     DAEQAF010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.249"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(197..>651)
                     /locus_tag="KRN00_003673"
     CDS             complement(197..>651)
                     /locus_tag="KRN00_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBH1829453.1"
                     /translation="LSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATLQGTIYGILM
                     FILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEFISTFGTTGK
                     GMRFLDLGFGFYFTVPIFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
BASE COUNT          257 a          101 c           51 g          242 t
ORIGIN      
        1 ttttataaaa aaatgtgctt ttaatatcta ctaataaagt tctttatttt aattaaaaca
       61 taattatatt ttagtattat aatcttttaa ttttagcatt atagtttatg tattataccc
      121 taatatattt tattttaaat tactagttag tcactctttt cgggttattt atctcctata
      181 tattaaagtg tcacacctaa atagttaaat cattatcctc ttttatcttt attgccttta
      241 caaatccatc tgcaattaca aaactcatca gagaagttat aaaatataca aatattggaa
      301 cagtaaaata aaatccaaat cctaaatcta gaaatctcat tccttttcca gtagtaccaa
      361 aagttgaaat aaactcaatt agagagttta aaagcaaaag atatccaata atcctaaatc
      421 tttttacatt ctcttttaca aataggctat attcagaact acctaatact tctatcaatg
      481 attttataat gataaaatat gatacaccta aaataaacat taatattcca taaatagtac
      541 cttgtagagt tgcttctcca ctaaaacaga ggtacataaa acttttaaat cctcctgcaa
      601 caattactaa tcctaaaaga aaaaataaaa tttgtaatat accacttagt a
//
LOCUS       DAEQAF010000227          638 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.252, whole genome shotgun sequence.
ACCESSION   DAEQAF010000227 DAEQAF010000000
VERSION     DAEQAF010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.252"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            272..388
                     /gene="rrf"
                     /locus_tag="KRN00_003674"
     rRNA            272..388
                     /gene="rrf"
                     /locus_tag="KRN00_003674"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            394..482
                     /locus_tag="KRN00_003675"
     tRNA            394..482
                     /locus_tag="KRN00_003675"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:428..430,aa:Leu,seq:taa)
     gene            494..570
                     /locus_tag="KRN00_003676"
     tRNA            494..570
                     /locus_tag="KRN00_003676"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:528..530,aa:Ile,seq:cat)
BASE COUNT          213 a          108 c          138 g          179 t
ORIGIN      
        1 gataggtcga aggtgtaagt gcagcaatgt atttagctta tcgatactaa taggtcgagg
       61 acttgaccaa tattatttga tgtcattcat taagatatat gtgcagtttt tagagtgcta
      121 actctatatt tttaaacttg tcaaaactta tggattttta atagttttat aaggcaaaaa
      181 atcgaataaa aaaagtattg acacaataag acaaagatgt tattataata cttgtcttag
      241 aaaaaaagtt aaatgaaaat ttagacaata atctggttat aatagcagag aggatacacc
      301 tgttcccatt ccgaacacag aagttaagct ctctagcgct gatggtactt ggtgggaaac
      361 tgcctgggag agtaggacat agccaggtga tgtgccgaag tggcggaact ggcagacgca
      421 caggacttaa aatcctgcgg gacttacctc tcgtaccggt tcgattccgg tcttcggcac
      481 cacaaattat tgtgggccat tagctcagtt ggttagagcg cccggctcat aaccggtagg
      541 tctggggttc gagtccctga tggcccacca caataattta aagaactttg aaaattaaac
      601 agtaggttaa tttataaaac aagaaacaaa ccataaag
//
LOCUS       DAEQAF010000228          577 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.261, whole genome shotgun sequence.
ACCESSION   DAEQAF010000228 DAEQAF010000000
VERSION     DAEQAF010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.261"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            <1..>577
                     /locus_tag="KRN00_003677"
     rRNA            <1..>577
                     /locus_tag="KRN00_003677"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          121 c          190 g          112 t
ORIGIN      
        1 caggatggac ccgcgtctga ttagctagtt ggtaaggtaa cggcttacca aggcgacgat
       61 cagtagccga cctgagaggg tgatcggcca cattggaact gagacacggt ccaaactcct
      121 acgggaggca gcagtgggga atattgcaca atgggcgaaa gcctgatgca gcaacgccgc
      181 gtgagtgatg aaggccttcg ggtcgtaaaa ctctgtcctc aaggaagata atgacggtac
      241 ttgaggagga agccccggct aactacgtgc cagcagccgc ggtaatacgt agggggctag
      301 cgttatccgg atttactggg cgtaaagggt gcgtaggcgg tctttcaagt caggagtgaa
      361 aggctacggc tcaaccgtag taagctcttg aaactgggag acttgagtgc aggagaggag
      421 agtggaattc ctagtgtagc ggtgaaatgc gtagatatta ggaggaacac cagttgcgaa
      481 ggcggctctc tggactgtaa ctgacgctga ggcacgaaag cgtggggagc aaacaggatt
      541 agataccctg gtagtccacg ctgtaaacga tgagtac
//
LOCUS       DAEQAF010000229          549 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.264, whole genome shotgun sequence.
ACCESSION   DAEQAF010000229 DAEQAF010000000
VERSION     DAEQAF010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.264"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..>549)
                     /locus_tag="KRN00_003678"
     rRNA            complement(<1..>549)
                     /locus_tag="KRN00_003678"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          127 a          153 c          130 g          139 t
ORIGIN      
        1 tcccgtggtg tgacgggcgg tgtgtacaag acccgggaac gcattcaccg cagcattctg
       61 atctgcgatt actagtaact ccagcttcat gtaggcgagt ttcagcctac aatccgaact
      121 gagagtagct ttaagggatt agctccacct tacggcttgg caaccctctg tactacccat
      181 tgtagcacgt gtgtagccct aagcataagg ggcatgatga tttgacgtca tccccacctt
      241 cctccaggtt atccctggca gtctctctag agtgcccaac ttaatgatgg caactaaaga
      301 caagggttgc gctcgttgcg ggacttaacc caacatctca cgacacgagc tgacgacaac
      361 catgcaccac ctgtcaccaa tgtccccgaa gggaactctc cgattaagga gatgtcattg
      421 ggatgtcaag cttaggtaag gttcttcgcg ttgcttcgaa ttaaaccaca tgctccgcta
      481 cttgtgcggg tccccgtcaa ttcctttgag tttcactctt gcgagcgtac ttcccaggcg
      541 gagtactta
//
LOCUS       DAEQAF010000230          374 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.358, whole genome shotgun sequence.
ACCESSION   DAEQAF010000230 DAEQAF010000000
VERSION     DAEQAF010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..374
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.358"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..372)
                     /locus_tag="KRN00_003679"
     rRNA            complement(<1..372)
                     /locus_tag="KRN00_003679"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           87 a          102 c           63 g          122 t
ORIGIN      
        1 aggactatta ccttctgtgg tgggtctttc caaacctctt caattacgat acctcttcgt
       61 tatgatatgt ccgcaacccc aataaagaaa actttattgg tttgggctaa tccgcgttcg
      121 ctcgccgcta cttacggaat cgaatttctt tctcttcctt caggtactta gatgtttcag
      181 ttccctgagt tcccctcatt aagctatgta ttcacttaat gatacttaga cattactcta
      241 agtgagtttc ctcattcgga aatcttcgga tcaaagttta cgtgcaactc cccgaagctt
      301 atcgcagctt atcacgtcct tcatcggctc ctagtgccaa ggcatccgcc ctgcaccctt
      361 aataacttga ccag
//
LOCUS       DAEQAF010000231          373 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.361, whole genome shotgun sequence.
ACCESSION   DAEQAF010000231 DAEQAF010000000
VERSION     DAEQAF010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.361"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            177..293
                     /gene="rrf"
                     /locus_tag="KRN00_003680"
     rRNA            177..293
                     /gene="rrf"
                     /locus_tag="KRN00_003680"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            300..371
                     /locus_tag="KRN00_003681"
     tRNA            300..371
                     /locus_tag="KRN00_003681"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:332..334,aa:Asn,seq:gtt)
BASE COUNT          118 a           61 c           80 g          114 t
ORIGIN      
        1 tttgatgtta ttcattaaga tatatgtgca gtttttagag tgttaactct atgtaaagta
       61 ctaacttcaa ttgatgaagt atatatcgta aaaacaatta ctatttagta cttcaaaact
      121 attgacattt aaaaataaag atgttaatat aatacttgtc ttataaatag gcaatatgtg
      181 gttataatag caaagaggat acacctgttc ccattccgaa cacagaagtt aagctcttta
      241 gcgctgatgg tacttggtgg gaaactgcct gggagagtag gacgtagcca cgtgaatatt
      301 ccaaggtagc tcaatggtgg agcaaccggc tgttaaccgg taggctgtgg gttcgagccc
      361 cacccttgga gcc
//
LOCUS       DAEQAF010000232          311 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.denovo.526, whole genome shotgun sequence.
ACCESSION   DAEQAF010000232 DAEQAF010000000
VERSION     DAEQAF010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.denovo.526"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(<1..>311)
                     /locus_tag="KRN00_003682"
     CDS             complement(<1..>311)
                     /locus_tag="KRN00_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBH1829454.1"
                     /translation="MALGVYITYKILDFPDMSADGSYTMGASIVAFSLTNGISPVVAT
                     LMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLRIMGKSNIPLFSFKHLF
                     NG"
BASE COUNT          125 a           55 c           46 g           85 t
ORIGIN      
        1 ccattgaata agtgtttaaa gctaaataga ggaatatttg attttcccat tattcttaaa
       61 ttgatagagt atagcattcc cataactaaa ataccagaaa gtaaattaga tatcttaaac
      121 ttaatgtgaa gaatccctgt aacaagacca gcagtacaac cacataagat agccattaaa
      181 gttgctacta caggagaaat accattagta agagaaaatg ctacaataga agcacccatt
      241 gtatagctac catcagcaga catatctgga aaatctaaga ttttgtaagt tatataaacc
      301 cccagtgcca t
//
LOCUS       DAEQAF010000233        49110 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.guided.016, whole genome shotgun sequence.
ACCESSION   DAEQAF010000233 DAEQAF010000000
VERSION     DAEQAF010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49110
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.guided.016"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            complement(422..1414)
                     /locus_tag="KRN00_003683"
     CDS             complement(422..1414)
                     /locus_tag="KRN00_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1829455.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(1423..2481)
                     /locus_tag="KRN00_003684"
     CDS             complement(1423..2481)
                     /locus_tag="KRN00_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBH1829456.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNGEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            2606..4069
                     /locus_tag="KRN00_003685"
     CDS             2606..4069
                     /locus_tag="KRN00_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBH1829457.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIKKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIYDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            4171..4968
                     /locus_tag="KRN00_003686"
     CDS             4171..4968
                     /locus_tag="KRN00_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBH1829458.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            4981..7083
                     /locus_tag="KRN00_003687"
     CDS             4981..7083
                     /locus_tag="KRN00_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBH1829459.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVIMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTITSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            7151..7630
                     /gene="rlmH"
                     /locus_tag="KRN00_003688"
     CDS             7151..7630
                     /gene="rlmH"
                     /locus_tag="KRN00_003688"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBH1829460.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLPVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSRMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            8519..9781
                     /gene="tetA(P)"
                     /locus_tag="KRN00_003689"
     CDS             8519..9781
                     /gene="tetA(P)"
                     /locus_tag="KRN00_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003479690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter TetA(P)"
                     /protein_id="HBH1829461.1"
                     /translation="MVNKLSAYKTYLLFSAITAMCFSLVATVMIVYHIETVHLNPLQL
                     ILVGTTLEVACFIFEIPTGIVADVYSRKLSIVIGVVLTGVGFILEGSISSFVFVLVAQ
                     IVWGLGSTFISGSVEAWIAEEEKDKDLDKIYIKGAQAGQIGSVIGIVLSTVIANLSVR
                     LPIIVSGVLFIILALFLWLYMPENNFKSSAPEDLNTFKKMGYTFKSGLKFIKNKPIII
                     ILLSVTLFYGLSSEGYDRLSNMHFLQDTMLPKLGNLKPVTWFGIFGIAGMILSAIVMH
                     FMEKKLKDDDKNKNGKLLLCINIFYISFMFIFAITKRFNLMLIAYLATSTFRTINEPI
                     FSAWLNGHIDDKARSTVLSINGQINSLGQILGGPIIGIIATNISVSMGIACTSLLVTP
                     VLVLYIVAMIMDKKVVDRVGGIDYEENN"
     gene            9765..11723
                     /gene="tetB(P)"
                     /locus_tag="KRN00_003690"
     CDS             9765..11723
                     /gene="tetB(P)"
                     /locus_tag="KRN00_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012478245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein TetB(P)"
                     /protein_id="HBH1829462.1"
                     /translation="MKKIINIGIVAHVDAGKTTITENLLYYSGAIKSVGRVDLGNTQT
                     DSMELERKRGITIKSSTISFNWNNVKVNIVDTPGHVDFISEVERSLSVLDGAILVISG
                     VEGIQSQTRILFETLKELNIPTIIFVNKLDRIGANFNKVFEDIKKNMSNKVVRLQEVY
                     DVGSKAVYIKKLFDTCMINDDAIDVLSDLDEAFLERYIGGIEPDKEEIQEKLSLYASE
                     GSLYPVFCGAAAIGLGVEDLLDGICSYFPFAGDDCESDLSGVVFKIERTSKNEKKVYV
                     RLFGGKISVRDKIQVPNKEIAEKVKKINRLENGGVVEAQRIEAGDIGILYGLTSFQVG
                     DVIGISNDKIKNISIAKPALKTTISAIDKEKNPELFKALTLLAEEDPLLELEMNDIDK
                     EIYVNLFGEVQMEILSSMLDDLYGIKVEFSNIETIYKETPKGFGASIMHMQEDLNPFW
                     ATVGLEIEPAGRGEGLRYISNVSVGSLPKSFQNAIEEAVIKTSKQGLFGWEVTDVKVT
                     LSCGEFFSPASTPADFRNVTPMVFMEALYKAQTVLLEPLHEFELKIPQNALSKAVWDL
                     ETMRATFDNPIVIGDEFSIKGLIPVENSKEYKMKIASYTEGRGMFVTKFYGYKEASAE
                     FSKARKKTTYDPLNKKEYLLHKLNAIRD"
     gene            11915..12193
                     /locus_tag="KRN00_003691"
     CDS             11915..12193
                     /locus_tag="KRN00_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829463.1"
                     /translation="MKIDFKITKDDYISFNLHHLENSKSQKSTFNILRYAVPIILSIP
                     IYFTGTGIFNQPSIYWIIVAIVFLVIWILTYPKQYKKLVAKETDKLIS"
     gene            12630..13811
                     /locus_tag="KRN00_003692"
     CDS             12630..13811
                     /locus_tag="KRN00_003692"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829464.1"
                     /translation="MGERKVNLDVSNEIYLRMIKEGYSPEDIKEMVIEEFNQFFMNNQ
                     VLERNAIDVLLPELINLTKLKQYGKYYREFTMCLDMYKNSMNIDKEECFKAFANWSSD
                     INKAINKYWIIYNLDKVREKLTIEEYVEVTFKKIGKLIEGIIKPYSFNILNNIYIIKG
                     KKEKVNTFERKDLGTFFEEIIQSNITGELFRIQLDTISGIKEIKLNQLRNIVAHENYE
                     IEGEIINCFIKNKNEIKDSFRISIEQLKKCFGDVYYTLGAIKLAYTIFFVDNIDEIIK
                     YNPDKSIIRVEQLITNTFLGIQSQGFKIIDFVEDSIESKLILKDALCDNEKQRMIHSS
                     QFLFRLWEITKAKNNVIEYLDNTGKLKAIFQLDSNVCERINNGELEPLAQAEMMKIKI
                     I"
     gene            13951..14682
                     /locus_tag="KRN00_003693"
     CDS             13951..14682
                     /locus_tag="KRN00_003693"
                     /inference="COORDINATES: protein motif:HMM:NF024800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBH1829465.1"
                     /translation="MKCPVCGASMTVSRSTRKIKDGTEAVNEYYACGNWTNKGTAVCN
                     SNSVKAEVADEVVINNLIEKVNNEILLKRIIDNINKNKSSKLKPKLDETNLVNKEIDK
                     LNGKKNSNIELFEDGILTKSELAERVKKLNEEIDTLKFRLDEIKQDVMLAEGEPAPFE
                     LVSQVMKQFGQVFKESSTRQQRKQLLNLLVSKITIDKLRAIDTIELQINEDIISYLFK
                     EGSFKEDPSFFSTFIINCSCFKFTI"
     gene            14898..15209
                     /locus_tag="KRN00_003694"
     CDS             14898..15209
                     /locus_tag="KRN00_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1829466.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            15257..15574
                     /locus_tag="KRN00_003695"
     CDS             15257..15574
                     /locus_tag="KRN00_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBH1829467.1"
                     /translation="MDEKIIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            15787..16488
                     /locus_tag="KRN00_003696"
     CDS             15787..16488
                     /locus_tag="KRN00_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBH1829468.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKKTIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            16712..18013
                     /locus_tag="KRN00_003697"
     CDS             16712..18013
                     /locus_tag="KRN00_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBH1829469.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            18150..19244
                     /locus_tag="KRN00_003698"
     CDS             18150..19244
                     /locus_tag="KRN00_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBH1829470.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIMLLDFIEPWSKFKLILEGE"
     gene            19246..20379
                     /locus_tag="KRN00_003699"
     CDS             19246..20379
                     /locus_tag="KRN00_003699"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBH1829471.1"
                     /translation="MKIDILIKGGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELKRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            20397..21506
                     /locus_tag="KRN00_003700"
     CDS             20397..21506
                     /locus_tag="KRN00_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBH1829472.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            21571..22311
                     /locus_tag="KRN00_003701"
     CDS             21571..22311
                     /locus_tag="KRN00_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBH1829473.1"
                     /translation="MNCIPQYYKNRVCLNVLAESIKNAKEVYDACDGHVLIGVLSKNY
                     STVEVAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            22316..23308
                     /locus_tag="KRN00_003702"
     CDS             22316..23308
                     /locus_tag="KRN00_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBH1829474.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYIITGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIGIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGVGDGYVV
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(23496..24377)
                     /locus_tag="KRN00_003703"
     CDS             complement(23496..24377)
                     /locus_tag="KRN00_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBH1829475.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            24650..26038
                     /locus_tag="KRN00_003704"
     CDS             24650..26038
                     /locus_tag="KRN00_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829476.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYADGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            26066..27019
                     /locus_tag="KRN00_003705"
     CDS             26066..27019
                     /locus_tag="KRN00_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBH1829477.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            27079..27303
                     /locus_tag="KRN00_003706"
     CDS             27079..27303
                     /locus_tag="KRN00_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829478.1"
                     /translation="MNEKPSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIGQAREATNYNIGNG"
     gene            27296..27808
                     /locus_tag="KRN00_003707"
     CDS             27296..27808
                     /locus_tag="KRN00_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBH1829479.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            27840..28694
                     /locus_tag="KRN00_003708"
     CDS             27840..28694
                     /locus_tag="KRN00_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBH1829480.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            29228..30022
                     /locus_tag="KRN00_003709"
     CDS             29228..30022
                     /locus_tag="KRN00_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBH1829481.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            30126..30932
                     /locus_tag="KRN00_003710"
     CDS             30126..30932
                     /locus_tag="KRN00_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBH1829482.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            30994..31515
                     /locus_tag="KRN00_003711"
     CDS             30994..31515
                     /locus_tag="KRN00_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBH1829483.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            31930..34017
                     /locus_tag="KRN00_003712"
     CDS             31930..34017
                     /locus_tag="KRN00_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBH1829484.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMEDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            34032..34319
                     /locus_tag="KRN00_003713"
     CDS             34032..34319
                     /locus_tag="KRN00_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBH1829485.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            34346..35617
                     /locus_tag="KRN00_003714"
     CDS             34346..35617
                     /locus_tag="KRN00_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBH1829486.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYGLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYAAGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            35675..36274
                     /locus_tag="KRN00_003715"
     CDS             35675..36274
                     /locus_tag="KRN00_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBH1829487.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKILKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQQYLKWHPAGSLGKSIREGI"
     gene            36279..37184
                     /gene="dapA"
                     /locus_tag="KRN00_003716"
     CDS             36279..37184
                     /gene="dapA"
                     /locus_tag="KRN00_003716"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBH1829488.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKAQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            37290..37922
                     /locus_tag="KRN00_003717"
     CDS             37290..37922
                     /locus_tag="KRN00_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBH1829489.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGETLCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGINIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNANKIREIIKNIRKI"
     gene            38400..40907
                     /locus_tag="KRN00_003718"
     CDS             38400..40907
                     /locus_tag="KRN00_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBH1829490.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAECPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNRNYQDYEDYEKFFEDES
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSMI"
     gene            41249..43411
                     /locus_tag="KRN00_003719"
     CDS             41249..43411
                     /locus_tag="KRN00_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBH1829491.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVTISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            43416..44033
                     /locus_tag="KRN00_003720"
     CDS             43416..44033
                     /locus_tag="KRN00_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBH1829492.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLELSEQADRVIKL"
     gene            44222..44566
                     /locus_tag="KRN00_003721"
     CDS             44222..44566
                     /locus_tag="KRN00_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBH1829493.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            45136..46002
                     /locus_tag="KRN00_003722"
     CDS             45136..46002
                     /locus_tag="KRN00_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBH1829494.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPIDK
                     ESGKPCINLQPDFKCSVHNSLMKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESVMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            46115..46519
                     /locus_tag="KRN00_003723"
     CDS             46115..46519
                     /locus_tag="KRN00_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBH1829495.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEAIPINVGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            46683..47132
                     /locus_tag="KRN00_003724"
     CDS             46683..47132
                     /locus_tag="KRN00_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBH1829496.1"
                     /translation="MKSGIILEMKQINSIEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(47288..47665)
                     /locus_tag="KRN00_003725"
     CDS             complement(47288..47665)
                     /locus_tag="KRN00_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1829497.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            47927..48844
                     /locus_tag="KRN00_003726"
     CDS             47927..48844
                     /locus_tag="KRN00_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBH1829498.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
BASE COUNT        19063 a         5285 c         8570 g        16192 t
ORIGIN      
        1 aatcagcagg ttgtaggttc gattcctatc accagctcca caaagtacat aaattcaaat
       61 taatataatt ttctatgtta caggatactt ttaagtatct ttttttaatt tcatttttat
      121 tgtattaaaa atgaaattaa acatacaaca aaattttgaa ttacttgcaa tgtgatagtt
      181 ttaaatataa aatttagaat cattctagca tagtattatg taatatagca aatttaattt
      241 atagtatcaa taaatataga ctactaagaa tgtaatgatt tgttagatta agatacatta
      301 gatatgtaaa tagaaaaata aaaagtatgt tttaatttat gtggcataag ttttaaacag
      361 agaagcaagt ttgctcttac ctctctattt aaaaataaaa aaatgttttt taagggctat
      421 tttatttaaa tctttcccat ctcaaatcat ctccagtaaa ttctaaaatc ctaaacttat
      481 ctaagattct agagagagtt ctttgagtgt aagtatttcc tatttgagat ggtgttaagt
      541 tggttgaaat aatgattttt ttaccagcaa caagtcttgt atttacaata ttgaagattt
      601 ctccactagt aaaagaatta ttaagttcag ttccaaggtc atctattatt aataaatcac
      661 aatcaaacaa gtttttataa ttatcttcac ttatttgatt atttgtgtct cttctaaatt
      721 tataatcttc aagaatatct aaaattctaa aagaagtttg atagattaca acattgcctt
      781 tatctaacaa ttcctttgca atacaattgc acatataggt ctttcctagt ccagtagaac
      841 cataaaacag tagattttca ctattatcct tcttaaaatc atgaacaaaa ttttcgcaga
      901 tacttaaatt atttagcata ttttctctag gagatatttc accatcagag cctttcttag
      961 gagaaaatat attcaagtta aaattcgaaa aattttcctg acttaaaatc ctatctaaat
     1021 tagacatttt ataagcttca tttacaattt cttgtttgag gcaagaacat ttttctccat
     1081 taggtaaaaa tcctttatct ttacaagaaa tacattgaaa ctttatttcc aagtaatcaa
     1141 gaggtatgtt actttcagct aaaagtcttt ctttctttac ttttaaagac tctatattct
     1201 ctttagtctt ctttacaatt tcatctttag acttgggatt taaaagtact atcttagcta
     1261 aactgagacc tattttagaa atttcatcat ctatagattt tatctcaggg attctattat
     1321 atacctcatt ttttctatgt tctaataaga gttcattatc atctcttctc ttagcatatt
     1381 tagcaagtat ttttcttatt ttatcctcat tcatttaatc acctacttaa acttttcttt
     1441 ttgacttttt ttaataatct catcgagctc atcagaggta tactgagtga atgtttcgtt
     1501 gaaattatga aacttagttt ttttgtaagt attgttgttt tgagtagtat taatctgctt
     1561 cttattaata ttctccttaa ctatacgttc ttcctctttt tgctttaaat catttaaatt
     1621 ttttatattt ttttcattcc aatttttaat tatgccattt atataagata tacttgggtt
     1681 tgaaatattc ttagacttag aacatgcatt tattatcaaa tctatatcca tattaaattt
     1741 atcaaaccag gtgtccataa gttctttttc tgattttgat ggttgtcttg aaaatcccaa
     1801 ttcattgaaa atcgttttat ataaaatata tcgttcactt cttaccaaaa agctttcttc
     1861 aacatctttt ggcgtatata aatttgaatc ataccaattt ctaataatgc cttcaatgta
     1921 tttaactggc tttgatgtac cagttttatc tttgacgtat tcatatgcgc aaagtatcat
     1981 atcggggctc atattgtatt tattcattat atccataata ctcatctttt cacttgggtc
     2041 gagatatcgc ccaactattt tatttataga attaaacatt tttctaatac ttggattttc
     2101 agaagtagat acaaccttat ctgtattaga ttttatagat gaattattgc ttaatatatt
     2161 ctcaatatag aaatttttta aatctaaaaa ttctattgaa taattaaaat tatcatattc
     2221 tccattgtca tgtattttta taatcttctt ttcttcccag aatttccaag cagataacac
     2281 atcagacaat ggtatattta ggtttttggc tattgaatta ttgtcgaact taggattaga
     2341 agtaatatca catgcttgtc tatatcctaa aagataaact tttacgtata acccgtccgc
     2401 cattggcata aatatatcta taaagatatt gggaatagtg atttcaccta aatctatttc
     2461 attgctttct ttaaaaaaca ttttatcacc tcagattaaa ttatatcatt ttttatatta
     2521 tatttgtctg taaacaaata aaaggtcaca agattagcat gtaaatattt tctaaaagta
     2581 ttcattttga aaaggaggag atattttggt tataaaattc aaccaaaaag taagaagaac
     2641 attatcagta gcgattctat ttatggtatt aataataggt tgctttataa aaaaggatga
     2701 cagtttagaa acatacaaag aaaaaactaa ttcaaaaata aatcagtata atatggatgt
     2761 tatatttgat gatgagacta agaggttaat gtgcaatcag aatgttgact acataaataa
     2821 tacaaaatca aacatagata aaatatattt ccatatatat ccgaatgctt tttccaagaa
     2881 agattttgct ccttttgaaa aaagtgaaat gacaagggct tatcctaatg gatttaacga
     2941 aggatatata gatataaaga atatattaaa taataatagt aaaatggagt ataaaattaa
     3001 aggagacaaa aatgacatat tagaaataga attagggaaa gagttaaaac caaatgaaag
     3061 aatgtcatta gatataaaat ataacgtaaa aataccaaat tcaattggaa gatttggata
     3121 tggagaaaat actataaatg ttactaattg gtttcctata gcttgtgtaa atgatgaaag
     3181 gggatggaat ttaaagagtt atgaaactat tggcgaccca ttttatagtg agactagcga
     3241 ttttcatgtg aaactattga ttccaaataa atataaaatt gctcatacag gaaaacttat
     3301 ttatgataaa catgataata agaaaatgct atatgaaata gaagctgaaa acgttagaga
     3361 ttttgcattt atactaagta gtaaatttga tgtaaacaaa gtagattcaa aaggagtagc
     3421 tatcaataca tataatttaa ataaaaagct ttctaaaaaa gcaactgaag tggcaaaaga
     3481 ttcaataaat atatttagtg aattatttgg aaagtatcct tacaaagaat tttctgttgt
     3541 agcaagtgac ttttttatag gggggatgga ataccctatg cttgttatga tagaccaaag
     3601 tttatataat gaaaaaaatg aatttttact agaatatgtt attgcccatg agacagcaca
     3661 tcaatggtgg tattctgctg ttggaaatga tgaaataagt gaaccctggt tagatgaagc
     3721 acttactgaa tattctacaa tagtttattt tgaacaaaag tatggtaaag atatggcaaa
     3781 caagcttata aaaactatgg agatacagac aaaaagttat ttgagcgaaa atatatttaa
     3841 gccagcaaat gagtataaaa attctactga atacagcttg aatgtttata caaaaggcgc
     3901 aatagcattt aatgaaataa gaaaagaagt tggagataaa gtattctttg agactttaaa
     3961 tgagtactat aataaatata agcataaaaa tgctaatgga agagcctttg tggaactatg
     4021 gaatagtaaa ggtgtagata taaataagat tataagtgaa tgtaagtaaa cagtgaatgt
     4081 aagtaaattt tgtgtagagt attaaatttt atttaatact ctgttttttt ggtataatat
     4141 aatttataag gcagaaaaag aggtgaagga atgctaaagt attgttcagt agggagtggt
     4201 agtagtggta attgccacta tatagggtat aaaaatacta atatactagt agatgcagga
     4261 ttaagtggca agagaataac tacaggtctt aaagacattg gtgtagatgc agataaatta
     4321 aaaggaatat ttataacaca tgagcatgtt gaccatataa aaggagcagg tatattatca
     4381 agaaagtttg atataccagt atttgctaat ataaaaacat ggtgttctat gaaggacaaa
     4441 ttaggtgaca tcaaagataa gaatatgaaa gtatttgaaa atgataaaac ctactcatta
     4501 ggtgatatca tagtaagacc tttttcaata gaacatgatg cgtctgaccc agttggatat
     4561 aatttttata cagagagtga tgaaaaaatg tctatagcta ctgatatagg atgtataact
     4621 caaaatataa aaaaacatct atataaatct aaattagtag tattggaatc aaattatgac
     4681 cctaatatgc ttatgatggg ttcatataca tatgctttaa agaaaagagt aatgtcaagt
     4741 actggtcatt tatccaatga agatgcagct aatttctgcg ttgaacttat taatgaaggt
     4801 acagaatcta tattattagc acatttgagt aaagaaaata attttcctga gttagcgtat
     4861 gagacttcaa aaggagtatt agcatcaaat gatatagtag ttggacaaga tgtaaaacta
     4921 gatgtactat cacgaaatga tgtttctaat gtttatgaga tgaagtagag gtgaataact
     4981 ttgctaaaga gaaattttga aaatgttgag gataataaaa ttttatactc tataaagcag
     5041 ggtatgattt tagcgatacc tgctattatg actggttcaa ctgctcttgt aattttgaat
     5101 cttccaataa aggcttatca agaatattta tcaggcttgt ttaatggaga ggttacaaat
     5161 attcttaact ttataaatga ttctacttta ggaattattt cattaataat attattaaca
     5221 ataagctata gttatggaaa aatatatggg agcaagtata cagtacttgt tcctatagtt
     5281 gcaatgtgct cttttttagt attttcacat ggtaatgagc ttaattctta tatagaaata
     5341 tttaaaacaa agtggttatt tacatctata attgtttcta tgacatcttc tgtattgttt
     5401 gtaaaactta cagaatcttt tgttacaagt gtaaagtttc atacagaagg ggctgatgca
     5461 gactttaata tggtagtttc ggctatagtt cctttcataa tagtagtatt tttgttttct
     5521 atttttagag tgataatgat aagtctaatt ggcagttcaa actttcaaga tatattttat
     5581 aatttatttt caaatgtttt taataaaatg ggaacaaacc ttatgagtgc tctgttgttt
     5641 atttttttaa tgcactttat gtggtttttt gggattcatg gtagtaatgt attagatacc
     5701 gtcgcaaaaa atttatttga aaatagtatg gcaattaaca taaatttagt taataataat
     5761 caattaccaa cagaaatttt tactaagacc ttttttgata caatggtttt attgggagga
     5821 tgtggctctt tactatgttt agtaattgca atttttctta gtgaaaaacg tataaatgta
     5881 agaaagttag ctaaaattgc ttcaatacca gctcttttta atatcaatga gatgctagtt
     5941 ttcgggatac caattgtttt taactatatt atgtttgtac cttttgtaat tactcctata
     6001 atcttaacca tcacaagtta tgtggctatg tctacaggta ttgtaccatg tacagtttca
     6061 gctgtagaat ggacctcacc tatattttta agtggatata tgtctacagg ttcaataaga
     6121 ggtagtttgt tgcaagtatt taatttatgt gttggtgtta tgatttatat tccgtttata
     6181 aaaatgtcgc aaaatagata tacatatatg tttaaaaata atatagaaaa tttaacaaac
     6241 ttattaaaaa ggtatgaatt aacaggtgaa cagcctaatc ttctaaacca taatggtaaa
     6301 ataggttcaa tttcaaaaat gttggcatca gacttgaagt ttgctatgaa aagaggagaa
     6361 atagagcttt tttatcaacc acaagtcaat tataatggaa atgttgtggg agcagaggga
     6421 ttacttagat ggaaacattc aataggaggg ttcatttatc caccactagt tataattttg
     6481 gctaaagaag aagggttctt agatgaactt ggagagtata ttattaataa agcatgtatt
     6541 gatttaaaga agagtgaaaa gctattgaga aatcctgtta agttctctgt aaatatatct
     6601 ccagaccaac ttgatgaccc taagttacca gagcaaataa aaaatatcat tagtagtaat
     6661 gatataaatc ctaatatgtt aggtatagaa ataacagagc aaattgcatt atcaggttca
     6721 caaataatta ttgaacgtat caatgcgata cataacttgg gaataaagtt aattatggat
     6781 gattttggga tggggcatag ctctcttata tatcttcaaa ataataactt tgatatagtt
     6841 aaattggatg gttcattagt taaagagata cttacaaata aaagaagtag tgaaattata
     6901 atgactattg taaatctttc aaaaaattta gattttgata tagttgttga gtatgttgaa
     6961 aatatagacc aaagggataa gttatatggt ttaggatgtg aaatatatca aggatattat
     7021 tatagcaaag caataccttt tgaagagttt gtagaatatg caaatcaaga aagagagata
     7081 taattttata agagcttgta aattctagta atgcatagat ttgtaataaa attaagttta
     7141 ggagaaatat atgaatataa gtatagtagt agtaggtaaa attaaagaaa aatatttaaa
     7201 attaggtatt gatgagttta agaaaaggct ttctaagtat tgtaagttag aaattataga
     7261 gttggatgat gaaaaagctc cagagaattt gagtgttaag gaaatggaaa ttataaaaga
     7321 caaagaagga aagaaaattt tagggaagat aaagcataat agttatgtta tagccttggc
     7381 tattgatggg aaaggtttat cctctgaaga acttgctaag actatgagtg atttaccagt
     7441 tagaggtaat agtagtctct gttttataat aggaggttct ctagggcttt ctgatgaggt
     7501 tttaggaagg gctgattata ggttatcctt ttctaggatg acttttcctc atcagatgat
     7561 gagattgata ttgttagaac agatttatag ggcttatagg ataaataatg gagaaccgta
     7621 tcacaagtaa gtgcgaactt taccaaaatt ggatatataa atgaaaggta ggtctgcttt
     7681 aattctgcaa tgaaactcac aaaaatctaa aatttgaatt tttgtaggtt attgtagttt
     7741 tattcatagg ttcttcgttt ttcacctatt tcagcaaatt agaatttgtt ttttctaatc
     7801 tatagtattg aaagaaattg taaaacattc cacaaatata ttttttatat tcatttcaga
     7861 tttaggttaa agttagtagt tattcttttg tgtatataag ttatttgaag taataaagtt
     7921 tcaattgaat ttggataaat atgaatataa aagtattgaa aaaaaataaa agtttatata
     7981 taatgtaatt atactaaaat ataaacatga aaaatataaa tgtaaaggag atgtaaatat
     8041 gcgcaaagag gtagttttta actaaactaa ctgaataagg attattttaa aaagtatatg
     8101 aaaaaaatct tggataactc aaggtttatt tgtggtagaa acaattatta ataatattga
     8161 tattaccatg tctatttgtg tactctaaaa ataatcagta ttataatgag catattacat
     8221 ctttatttga agaataggaa aactgtgttc taaacacggt atttttatgc ctatttttac
     8281 tatatttata gatatgatat aagactttaa tttgcatagc ttaatcataa gttatataaa
     8341 ttaaagttgt atatttcatg tttatattta ggttatataa ttatgaggct gtaagtgaat
     8401 tatgttcact tacagctttt tttatttaag gagattattt tgatgattta tatatttaaa
     8461 tatgaagatt atgaaaaaca aataaatttt tttaaaaata ctaggatggt gattattaat
     8521 ggttaataaa ctttcagcat ataaaactta tttattattt tcagctatta cagcaatgtg
     8581 tttttcacta gtagctacag ttatgatagt gtatcacatt gaaacggtgc atttaaatcc
     8641 acttcagctt atacttgttg gaactacttt agaagtagca tgctttatat ttgaaattcc
     8701 tacaggaata gttgcagatg tgtacagtcg taaactatct attgttattg gtgtagtttt
     8761 aacaggagtg ggatttattt tagaaggttc tatttctagt ttcgttttcg tacttgtagc
     8821 acagattgta tggggattag gttctacttt tattagtgga tctgttgaag cttggattgc
     8881 ggaagaagag aaagataaag atttggataa aatttatata aagggagcac aagcaggaca
     8941 gataggatcg gttattggaa tagtactaag cactgtaata gctaatttat ctgtaagact
     9001 acctattata gttagtggag tcttatttat aattcttgca ttatttttat ggttatatat
     9061 gccagaaaat aattttaaat catctgctcc agaggattta aatactttta aaaagatggg
     9121 atataccttt aaatctggtc ttaaatttat aaaaaataaa cctataatta taattttgct
     9181 ttcagtaact ttattttatg gattatccag tgaaggttat gatagacttt ctaatatgca
     9241 ttttttacaa gatactatgc ttcctaaact tggaaacctt aaaccagtga cttggttcgg
     9301 aatttttgga attgcaggaa tgatattgag tgctatagta atgcatttta tggaaaagaa
     9361 gcttaaggat gatgataaga ataaaaatgg aaagctgtta ttatgtataa atatatttta
     9421 tatatcattt atgttcatat ttgctattac aaaaagattt aacttaatgc taatagctta
     9481 tttagcgaca agtaccttta gaactataaa tgaacctata tttagtgcat ggcttaatgg
     9541 acatatagat gacaaggcca gatctactgt actttctata aatggacaaa taaattcctt
     9601 aggtcaaatt ttaggtggac caattatagg aatcatagct acaaatattt cagtgagtat
     9661 gggtatagca tgtacttcgt tattagtaac accggtatta gtgttatata ttgttgctat
     9721 gataatggat aaaaaggtgg ttgatagagt tggaggtatt gattatgaag aaaataatta
     9781 atataggaat cgtagcacac gtggatgcag gaaaaacaac tataacagaa aacttattat
     9841 attatagtgg agctataaaa tcagttggaa gagttgattt aggcaataca cagacggatt
     9901 ctatggagct tgagcgtaag agagggatta ccattaaatc atcaaccata tcttttaatt
     9961 ggaataatgt caaggttaat attgttgata ctccaggaca tgtggatttt atttcggaag
    10021 ttgaacgttc attaagtgtt ttagatggag cgatactagt tatatcagga gtagagggta
    10081 ttcagtcaca aacaagaata ttatttgaga cattaaagga gttaaacatt ccaacaataa
    10141 tttttgtaaa taagctagat agaattgggg caaatttcaa taaagtattt gaagatataa
    10201 agaagaatat gtccaataaa gtagttagat tacaagaagt atatgatgta ggaagcaaag
    10261 ctgtttatat aaaaaaacta tttgatacat gcatgataaa tgatgatgct attgatgttt
    10321 tatcagactt agacgaagca tttttagaaa gatatattgg tggaatagaa cctgataaag
    10381 aagaaataca agaaaagctt tcattatatg caagtgaagg aagtctatat ccagtatttt
    10441 gtggtgcggc agcaattgga cttggagttg aagacttatt agatggaatt tgtagttatt
    10501 ttccatttgc aggtgatgat tgtgaaagtg atttatctgg agtagtattt aaaatcgaaa
    10561 gaacaagtaa aaatgaaaag aaggtttatg taagattatt tggaggaaaa atatctgtaa
    10621 gagataaaat tcaagtacct aataaggaga tagcagaaaa agtaaagaaa attaataggt
    10681 tagaaaatgg gggagttgtt gaagcacaga ggatagaagc aggggatata ggtattttat
    10741 atggacttac aagtttccaa gtgggagatg ttattggaat ttcaaatgat aaaattaaaa
    10801 atatatctat agctaaacca gcattaaaaa caacaatttc tgcaattgat aaagaaaaaa
    10861 atccagagct atttaaagca ttaacattac ttgcagagga agatccacta ctagaattag
    10921 agatgaatga catagataaa gaaatttatg tcaacttatt cggtgaagtt caaatggaaa
    10981 tactaagttc catgttagat gatttatatg gaataaaagt agagttttcg aatattgaga
    11041 ctatctataa ggaaacacct aaaggttttg gagcgtcaat aatgcatatg caggaagact
    11101 taaatccatt ttgggcgaca gtaggcttag aaatagaacc agcagggaga ggcgaaggtc
    11161 ttaggtatat ttctaatgtt tcagtagggt cattgccaaa atcttttcaa aatgcaattg
    11221 aagaagcagt tattaagaca agtaaacaag gattatttgg atgggaggtt acagatgtaa
    11281 aagtcactct tagctgtggt gaatttttta gtccagccag cactccagca gattttagaa
    11341 atgtgacacc tatggtattc atggaagcat tatataaagc acaaactgtt ttattagagc
    11401 cattacatga gtttgagtta aagattcctc aaaatgcttt aagcaaagcg gtatgggatt
    11461 tagaaactat gagggcaacc tttgataatc ctattgttat aggggatgaa ttctcaataa
    11521 agggattaat tccagtagaa aattcaaaag aatataaaat gaaaatagct tcatatacag
    11581 aaggtagagg aatgtttgtg acaaaatttt atgggtataa ggaagcttca gctgaatttt
    11641 caaaagcacg caaaaaaaca acgtatgatc cattgaataa aaaagagtat ttgcttcata
    11701 aactaaacgc aattagagat taaatttaaa tagataagtt aaatttttat atgtaggatt
    11761 taaatataag acattcaaag cctaaaagta aaggaagggt cgtctgaaga agatgaagac
    11821 ccttcctttt ttcatgttac tatgcttaat tgtaagtgct tgaaatttgt aatataatgt
    11881 aaataaagtt tttaataata aggggacggc acaaatgaaa atcgacttta aaataacaaa
    11941 agatgactat ataagcttca atttacatca tttagaaaac tcgaaatcac agaaaagtac
    12001 atttaacata cttagatatg ctgtacccat aatactttct ataccaatct actttacagg
    12061 aacggggata tttaatcaac cgagtatata ttggattata gtagcgatag tttttttagt
    12121 catttggatt ttaacatatc ctaagcaata caaaaaatta gtagctaaag aaactgataa
    12181 actcataagt taaggagata attcatcaat atttggaagt aagactttag aaattattga
    12241 tgggacaata gtagtaaaag gggattctat atcagaaaca gtatcgttag aaagtataaa
    12301 agatgtaaaa gtttacgaag atatgatcct tatatataag tggatttgta gctcatataa
    12361 ttccaaggag atatttagat aaagaaatag agaaagaact tatgaaagag cttaaaaaat
    12421 ataaggcttt agaacaatta aagtaaaacg tgctcctttg gaggtgtaac ggagaaccgt
    12481 atcacaagta acggagcgcg atagccttat caattgatat atcttgatta aggctatttt
    12541 catacataaa aatactgtat cataagtaat ataatataat tgaaaaatat cgtatagttg
    12601 taattgataa tgattaaagg agagcgttta tgggggaaag aaaagtaaat ttggatgtaa
    12661 gtaatgaaat ttacttaaga atgattaaag agggatattc accagaggat ataaaagaaa
    12721 tggtaataga agagtttaat cagtttttta tgaataatca agtactagaa agaaatgcaa
    12781 ttgatgtttt attaccagaa ttaattaact taactaaatt aaaacaatat gggaagtatt
    12841 atcgagaatt tactatgtgt ctagatatgt ataagaatag tatgaatatt gataaagaag
    12901 agtgttttaa agcatttgct aattggtcgt cagatattaa taaagcaata aataaatatt
    12961 ggattatata taatttggat aaagtaagag aaaaattgac tatagaggaa tatgtagagg
    13021 ttacatttaa aaaaattggc aaattaatag aagggattat aaagccttat tcatttaaca
    13081 tattaaataa catatatata atcaaaggta aaaaggaaaa ggttaataca tttgaaagga
    13141 aagatttagg tacatttttt gaagaaataa tacagtctaa tataacaggg gaacttttta
    13201 gaatacaatt agacactata agtggaataa aagaaataaa actaaatcaa ttaagaaata
    13261 tagtagcaca tgaaaattat gagattgaag gagaaatcat aaattgtttt ataaagaata
    13321 agaatgaaat aaaagactca tttagaatat ctatagaaca attaaaaaaa tgttttggtg
    13381 atgtatatta tacattagga gcaataaagt tagcttatac gatatttttt gttgataata
    13441 ttgatgaaat aattaagtat aatcctgata aatcaattat aagagtagaa cagttgatta
    13501 ccaatacctt tttgggaata caatcacaag gatttaaaat catagatttt gtagaagata
    13561 gtatagagag taaactaatc cttaaagatg ctttatgtga taatgaaaaa caaagaatga
    13621 ttcactcatc tcaattttta tttagattgt gggaaattac taaagctaaa aacaatgtaa
    13681 tagaatatct tgataataca gggaagttga aggctatatt tcaattagat tcaaatgtat
    13741 gtgaacgtat taataatgga gaattagagc cattagctca agcagaaatg atgaaaataa
    13801 agattatata aaaagctcat ttatcatcaa tatggagaac acgaaactat aatagataat
    13861 attacatggg aaaaggtaca gataatagta aaagatagaa ttaaaactca caatagagtc
    13921 taggatagtg agctaattct aagtagacta ttgaaatgtc ctgtgtgtgg agcctcaatg
    13981 actgtaagta ggtcaactag aaaaataaaa gatggaactg aagcagtaaa tgagtactat
    14041 gcatgtggga attggacgaa taaaggaacg gcagtgtgta actcaaactc tgtaaaagca
    14101 gaagttgcag atgaagttgt aatcaataat ctaatagaaa aagtaaataa tgagatactg
    14161 ctaaagagga taatagacaa catcaataag aataagtcta gtaagctaaa accaaaatta
    14221 gatgaaacta acttagtaaa taaagaaatt gataagttaa atggcaagaa gaactctaac
    14281 atagagctat ttgaagatgg aatattaact aagagtgaat tggcagagag agtaaagaaa
    14341 ctaaatgaag agatagacac attgaaattt agactagatg aaataaagca agatgtgatg
    14401 ttagcagaag gagaaccagc accttttgag ttagtaagtc aagtgatgaa acagtttggg
    14461 caagtattca aggagagtag tacaagacaa caaagaaagc agttgttaaa cttacttgtg
    14521 tcaaagataa ctatagataa attaagagca atagatacta tagaattaca aataaatgaa
    14581 gatataataa gttatttatt taaggaagga tcgtttaaag aagatccttc cttttttagt
    14641 actttcatta ttaattgcag ttgttttaaa tttacaatat aattaattaa gttaaaatat
    14701 taaaaatacg ctcctttggt agtgtaacgg agaaccgtat cataaataaa tgatacggtt
    14761 tttgttagtt tgcaacttaa taatattaaa ataacaaaaa agtattgaaa gtatattgca
    14821 tttaaggtag aattaaataa aatattataa cattataatg tttataaagt tgttaataaa
    14881 aatttggagg aaaatatatg ataaaaataa tgttggcctg ttcagcaggg atgtctacaa
    14941 gtttattagt tactaaaatg gaaagtgcag ctaaagaaaa tggtatagag tcgcaaattt
    15001 gggcaatacc agaatcaact atacaaaatg aaatagaaaa atgtgatgta ttattactag
    15061 gaccacaagt tagatatgta ttacctaagg ctcaagaaat tgctaagcca tataatatac
    15121 cagtagaagt tataaatatg atgcactatg gaacagttaa tggagaagct gttttaaata
    15181 gagcgataga acttaacaac actaagtaat ataaattata atgtattttt aatatataaa
    15241 ttgggagaat caaaggatgg atgaaaagat tatagaaata tcttttaata taataggtta
    15301 tgcaggtgaa ggtaaagggt tagcttttga agcaataaaa gaggctaaga atggaaatat
    15361 agaaaaagca aaagaattat taaaagagtc tagggaagtt ataaataaag cacatagata
    15421 tcaaacagaa ttaatacaaa acgaagctag tggaaacagg actgaaataa gtgtcatact
    15481 tatacatgca caggaccact taatgaatgg catgaatttt caacagttag ctgaggaaat
    15541 cgttgattta catttgaaat tacaagataa ataaaaatta aagataataa attaagagag
    15601 ttcttaaaag atacattatg tgtagcacac taattgttag attattgatt caatatttag
    15661 tgagtaatac attaggatta ttttgaggac tctttttata tttagtttaa agttaataaa
    15721 tatttattat taataatata agattatatg ttataatatt ataacatata atttaagagg
    15781 tgaatcatgt taagaaatca accattatat atacaagttg tagatatatt aaagcaaaaa
    15841 atattaaata acgaatataa aattgatgaa aatattccaa cagaaaggga gttagagcaa
    15901 gagtttggag tcagtaaaat tactattaga aaagctattg agatattaga atcagaaggg
    15961 tatgtagaga aaaaaagtgg aaaagggaca aaagtaataa gtaatagtct ttttaataag
    16021 ctatcaaaag cagagtcttt ttcaagtata cttttatcta aaggtcataa gttatctaaa
    16081 aagactattt caattgaaaa aataataaat gatacaaatt cacaagtatt tagtatattt
    16141 ggagaaaaat gtagcaagat tactagaatg tattacttag atagtaagcc atatatattt
    16201 tttactcatt atattccttt tgatgaaaat ctaactgttg aaagttttaa taatgaaagt
    16261 tctttatata tgtacttata taggagaaat ataaatataa ctagatttga agatgaattt
    16321 tttatagaag aatcagaact agaggtatca aaggctctaa atctagctaa agacatatta
    16381 ttaggaagaa aaagaaagac ctatgatgag aatgataata tagttgagct atcatttgca
    16441 agatataata cagaagtaca aaactatgta attaaatacg aaatataata agaatcctga
    16501 gtttattgaa atgataatat gctcaggatt tttgtttagt tgtaaaaata aaaaatatta
    16561 taacattata atgtttacaa ctaaacatta taatgttata atatttttaa taaacaagtg
    16621 atattatcaa ttacataaaa attagtttat gttatgaaat cgttattgca ttataaataa
    16681 aggataatat caataataca gggggataac tatggaaaaa ttcgcaagtt ttttagagcg
    16741 caagattatg cctgtagcag cgaagataag taatcagaga catatgagag ctgtaagagc
    16801 aggtataata gcaacattac cactaacaat agtggggtca tttttcacaa tattattaaa
    16861 catacctatt gatgcttata tggattttat agctccattt aaagcaatat tagatatacc
    16921 atttagatat actgtaggat ttttatctct atatgctact tttgggatag catcatcact
    16981 tgctaaaagc tacgatttag atacaacagg tgttggtatg cttgcagtta tggcattttt
    17041 agtttctaca atagttccaa ctcaagtagt tgaaccagta ggtggagtta tagaagctgg
    17101 tagatggatg gatatggcaa aacttaattc gccatcatta tttggagcta tcgtaacatc
    17161 attaattaca gttgaaatat atcgttttat gaaggaaaag aatattacaa ttaagatgcc
    17221 agcaggagtt ccagtagagg tttcaaattc atttactgca ttattaccga cagcagtaat
    17281 tttaatgtta ttctgggtaa taagacatat tttaggattt gatataagtg ttgcactaag
    17341 cgctatgtta tcacctttaa aaggattctt atcaggaaat agtttaggtg gtgggttact
    17401 gacagtattc ctaataactt tattctgggt acttggaata catggtccag ctataatggg
    17461 gccagtaata agacctatat gggacatgtc tatagcagaa aatataactg cattcacaga
    17521 aggagtatca gctcatgcaa tgccaaacat atttacagaa caatttttac agtggtatgt
    17581 atggataggg ggagcagggg ctactcttgc attagttgta atgtttatgt tttctaagtc
    17641 acaatatcta aaaagtttag gtagattagg atttttacca gggttattca acataaatga
    17701 acctataata tttggagcac caatagttat gaatccaata ctagggatac catttataat
    17761 tggacctata ataatgacaa ttctatcata tgttcttact attacagggg ttatacctat
    17821 gatggtagca agattaccat ttgcaatgcc agcaccaata gcagcagtaa tgagtactaa
    17881 ctggagtata ttagcaggta tcttagtatt aatcaacttt gtgatatcat ttgctgttta
    17941 ttatccattc ttcaaagttt ttgaaaaaca acaattacaa agagaacaag aagaaatgag
    18001 tgaaaattta taaaaataca tagatataga ggttttgtac tatataaaat atagaaaaaa
    18061 cttataagtt attaagggtg aaggtaggag gaatgacctt tgcctttaat tttatatatt
    18121 ttaaataatg taatttgagg aggagaaaga tggaaagaag attaggaata tcagtatatc
    18181 cagagcatag taacatggaa gatgataagg catatataaa aatggcttca aaatacggat
    18241 ttaaaagaat atttatgtgc atgctttcaa ttacaagacc taaggaagaa gttaaaaaac
    18301 attttaaaga gattataacc tatgcaagag aattaggatt tgaagtaatc cttgatatag
    18361 ctccaaacat atttgatata ttacaaatat cttatgatga tttaacattt tttagtgagt
    18421 taaatgctag tggaataagg cttgactatg gatatgatgg aagtaaagaa gctatgattt
    18481 ctttcaatcc atatgattta aaagtggaac taaatatgag taatgatgta gcatacttgg
    18541 ataatataat tacttacaag ccaaatgtaa ataatatata tggttgtcac aatttttatc
    18601 ctcaaagggg tacaggcttg ccatatgatt tttttgtaag atgttcaaat agatttaaaa
    18661 agtatggaat aagaactgct gcttttgtta attcaaaata tgcaacaatc ggaccttgga
    18721 atataaatga tggactgtgt acgcttgaaa tgcatagaaa cttagatatt gctacagcaa
    18781 ctaagcactt attcgcaaca ggattgattg acgatgtaat tgtagggaat gcatatgcaa
    18841 gtgaagatga attaaaaaga atgtctgaag taaataaata tcaagttgta tttaatgtag
    18901 taactgagga aaaaacttct gaagtagaaa agacaataat ggcaaatgag caacacttta
    18961 gaagagggga tataaccaac caagtagcaa ggtctacaga agtaagaaaa aaatatgcta
    19021 aagaaaattt ccctaagcat gataatacga ccatctttaa aagaggagat gtagtgattg
    19081 gtaatgatga ctttggaaag tataaagggg aattacagtt gatacttcaa gattgtgcag
    19141 atgaaagaaa aaataaggta ggtagaataa aggaagacga aataatgctt ttagacttta
    19201 ttgaaccttg gagtaaattt aaacttattt tagagggaga gtaaagtgaa gatagacata
    19261 ttaataaaag gtggaaaaac agtagataaa agtataattg atatagctat attagacgat
    19321 aaaataatag aagtaaaaaa tcagatagat gattctaagt atcaggcaaa tcaaattata
    19381 aacctagatg gagaaaaatt tattagtgct ggttggatag atatacatac gcattgctac
    19441 gaaagactag acctttataa ggattatcca gatgaggttg gaataaaaag cggtgttact
    19501 actgtagtag atgcaggaac aacaggagct ttagatatag gtaaatttta tgaagatact
    19561 aaaaaatata aaacaaatgt atatgcttta ataaatattg ctaagcaggg aataacatct
    19621 caagatgaac tttcaagtat gatgaatatt gatgaatatg aacttaaaag agcagttaaa
    19681 aaatacaaag attttgttgt tggaatcaaa gctagaatga gtaaaagtgt tgtaatttca
    19741 aatgatgttg aacctttaaa agtagctaaa agaataaaaa atgaacttaa tctacctatg
    19801 atggttcact ttgggagttc tcctccaacg atagaggata tatttgacta tatggaaaaa
    19861 ggagatatat taacccatat atataatgga aagccaaatg gaatacttag aggcaatgag
    19921 gttaaaaaag aaatcataga agctagagaa agaggtataa tccttgatgt aggtcatgga
    19981 accgaaagtt ttagtatgga tattgcaatg aaatctaagg atgcaggaat ttttccagac
    20041 actataagta cagatatata tattaaaaat agaataaatg gtccagtgta taatctatct
    20101 acaacaatgg aaaagtttat atatatgggc tattcacttg aagatataat agataaagtt
    20161 actaaaaatg cagcagatgc aataagttta aaaaataaag gtttaataaa agaaggatat
    20221 gatgctgatt taactatatt tgatgtggtt aatgaagaaa aagaacttca agattctttg
    20281 aataagtcag taatcacaag tacgtctata aagccaagag cagtagtagt caatggagaa
    20341 tatttaaata taggtaagtc tataggagag aatgagtaga agggagaaac tattgtatga
    20401 gtagtatatt tgaaaaatac tctgtaagac gtgttataaa tgcttcaggc aaaatgacta
    20461 tactaggagt atcaacagta gataaggaag ttattgaagc aataggtgaa gggtgtaaaa
    20521 atttctttat aatagaagaa cttataaata aaacaggtga atatatagca aatttattag
    20581 ggtgtgaaag tgcactaata gtttctagtg catctgctgg gattgcacag agtgtgggag
    20641 caatgatagc aaaagatgat atgagtctag tttacaatgt aaataatcct aagaaacaag
    20701 ttaaaaggga aataataatt ccaaagggac ataatgttga ttatggagtt ccagtagaag
    20761 taatgataag acttggagga ggagaagttg ttgaggccgg ttatgctaat atgtgtaaca
    20821 aggaacatat aataagagag ataaatgaaa atacagcagc aattatgtat attaaatctc
    20881 atcattgtgt tcaaaagagt atgctaagtg tattagatgc agtacaagtt gctaaagaat
    20941 ataatttacc tttgatagta gatgcagcag cagaagaaga tttaaatgta tattatgaat
    21001 tgggagcaga cctagtgata tacagtggtg ctaaggctat agagggtcct agctcagggt
    21061 tagtaatagg taagaaaaaa tacatagata atgtaaagct tcaatcaaag ggtataggaa
    21121 gagctatgaa aataggaaaa gaaaatattg taggtctaac atgtgcaatt gagagatata
    21181 taagtaatga taaagtaact ttaaaagaaa tggaggacaa gctaaatcca tttatagaca
    21241 agataaatac tataaaggga gtgagtgcta gtataactag ggattcagca ggtagagaaa
    21301 tacttcgtgg agaaattgac tttaatgaag atataataaa taagtcaaca caacaaatta
    21361 taaatgaact tagaagtgga gagatagcta tatacactag agactataag gctaatgaag
    21421 gcaagattga gattgatata agaagtgtaa ctggaagtga tttagatact atttataata
    21481 ggataaaaaa tatagtagaa agttagagtg tagagtaagt gacattataa tgatttaata
    21541 aattgaattt taccaatgga ggggataaat atgaattgta taccacaata ttataaaaat
    21601 agagtttgtt taaatgttct tgcagaaagc ataaaaaatg ctaaagaagt atatgatgct
    21661 tgtgacgggc atgtattgat aggagtacta tcaaagaatt acagcactgt agaagtagct
    21721 attgaagata tgaaaaaata ctcaaaggaa atagataatg caatatctgt ggggcttgga
    21781 gctggagacc caaatcagtc aaatatggta tctcagattt ctaaagaact tcagccacaa
    21841 catataaatc aagtgtttac aggtgtggct acgtctagag cattgcttgg tcaaaatgat
    21901 agtataataa atggattagt ttctccaact ggtaaaccag gatttgtaaa aatatccaca
    21961 ggtccattaa gttcaaaaga aaaagatggt atagttccta tagaaacagc aatagctatg
    22021 atgaaagata tgggaggaag ctcaattaag ttttttccaa tgggagggct taaaacaaag
    22081 gatgaatata tagaagttgc aaaagcttgt gcaaagcata atttttattt agaaccaaca
    22141 ggaggtatag acttagataa cttcaaagag atagttcaaa ttgcacttga tgctggtgta
    22201 gaaaaagtta tacctcatgt ttatacatca ataattgata aagaaacagg tgaaacgaaa
    22261 gtggaagata taggagtact ttataaaata atgaaagaat tattgggata gatttatgaa
    22321 tatattagct tttggtgaaa taatgatgag actttcagta cctgactaca agttcttaac
    22381 acaaaccaat gaactaaatt atataattac aggcacggga ttaaatatat tatctggact
    22441 taaaaacttt ggatacaata cctatatgtt gacaaagttg cctaataata atgtaggtaa
    22501 agcatcaagt gcaaatataa gaaagcttgg agtaaaagat gactttatca cgtatggagg
    22561 gaatcatata ggagtgtatt ttcttgaaaa tgggtatgga gaaagacctt ctgaagtgac
    22621 ttatttgaat aggttaaata gttcattttg tgagagtaaa ttacaagatt atgatattga
    22681 taaatgttta gaagaaatgg atatagtcca tatttgtggt attgctatgc aacttacaga
    22741 ttcagttaaa gagattgctt tagaactagc tagaaaatct tatgaaaagg ggataaaagt
    22801 attctttgat tttaatttta gacaatcatt aaatccagaa aggacttatg atgatttagt
    22861 aaatgattat aagaaaatac taccatattg tcatgggctg tttgctagtt atagagatat
    22921 aaataagata cttaatatag atagtctaaa tataaaatct agttcagaat tgattaaaaa
    22981 agagtatgat ataggtattg tagctggaac tatgagaaga tttgatgata tgaataatag
    23041 atttataaag ggatatatat caaatgatga tggttatttt gaaagtaggg agtataagtt
    23101 agaaatatat gacagggttg gtgtcggaga tggatatgta gtaggaatta tatattcata
    23161 tttggaaaat atgaagagtg aagatatagt tgagtttggg gttgctagtt cggtgttagc
    23221 tcatacaact tatggggata attctttagt aagcacaggt catgtactta gactgatgaa
    23281 caatgaaaaa atagatatat tgagataata catttgtata taataaaatt tttatctttt
    23341 ttagacacat ttttgacttg cttatatttg ttaaacagag ttatttttaa cgattataaa
    23401 tattaaatta aaagttaaat aataaaatag tagaaaatag cattaactat agaaaaaatg
    23461 gttaatgcta tttttatcgt taatattgat taattttata ttatagaaat gaacttttct
    23521 aatgctggat ttgtattttt tttattccat acaactacaa cttcaattct attttctact
    23581 tcttttatag gtactattgc aatatcacgt tctatcattg tatctgtaac acaaaatgaa
    23641 ggtaaaatgg atattcccat gttagaagat accaatgatt caatagtatt aagattattt
    23701 gaacgttgta ccacattagg tacaaaccct gcttcacgat atctattctg tatcattgac
    23761 ttttgtccat actcatcccc tgtttctttt acaaaaataa atttatcatg ttgtaattca
    23821 attaaatcga tagaatcctc attgtaaagt ggatgaccag gaggtaaaag agctaccaaa
    23881 gaatatcttt ctacagtttt atattcaaaa tcttttaatg gttgattttc tggattaata
    23941 acaaaagcga ggtccataga attatttttt actaagttta aaagttcggt tatctcatta
    24001 gtacaaatat ccatagatat attagggtat gtattagaaa attcttttaa atattgttga
    24061 agtttgtttt tttcgtatcc tattaaggtt ccaatgctca aagttccaaa aaaaccatgt
    24121 gcaaattgtt gtgtttttgc aatagcatca ttgatatttt ttattatagt acgtgcctca
    24181 gataaaaaaa cttttccagc tggtgttagt tcaacatgac gtttacttct tgtaaataga
    24241 gttacattta tttgttcttc taaagctttt atttgctgtg taacagcagt ttgagaaata
    24301 taaaattttt ctgctgtttt tgtaaaactt agattttctg ctacagatat aaaatattct
    24361 aattgtttag tattcaaata atcaccccta tttaaacttg attgtttgta aaccttattt
    24421 atctataatt aaagcttatt atagtataag aaaatttact tttaaagaat attagaaaat
    24481 atttgtataa aaatatatgt tttaagtata tctttacatt agattttata aatttattaa
    24541 taagaataac ttatatattc caatgaaaac gatattggat ttaagtaagt ttgtctcata
    24601 aaatgaaagt atatcaattg ataatacttt aaataagaag ggagaaaaaa tggaagataa
    24661 attttatgca aaaggcaacg gaaataacgg atatattaaa aatcttgaag tttgttcctt
    24721 taataactta gatggaactt gtggaatgtt tcaaatggct ctgtacaaaa gagatgaaaa
    24781 atactattta tatggatgct gttttggagg aaataaaaaa aatggagtaa tgattagcga
    24841 tattacagac ccttataatc cacaatttat aaaacatttt caaatgttag accctaaaga
    24901 gtatcctaca acaacaactc ccaaaattca aatagcagat gatttaatga tagtagcaat
    24961 gagttgtgga agtggaccag gagcacttgt tgaccaagct aaattagcaa atattaagtg
    25021 tgaagcagga attagaatat acagtttaaa agaagaccct ttaaatccta agtttttagg
    25081 atattgggat tgtggcttaa agcatgtaat gggtgttcat agattcatgt acaatggtgg
    25141 aagatatgta catttatcaa gtgattgtgt tggctttgaa ggtctgattt atagggtcat
    25201 agatataata aatcctacta atccagtgga aataggtaaa tggtggagac cagaccaata
    25261 tgcagatgga tatccaaata gaacttttga tgcaggagca cctcattgcc cagaatttat
    25321 ggataaagga tggcttcatg gacctccatt tgtaagagat ggaaaagcat attgtggtta
    25381 tggaggagct ggtttagttg tattagatgt tgaagattta acaagaccaa gatgcttagg
    25441 tgaattgcca tttatgcctg cattttctag tagacttgca ggtgcaagaa ctcatacagc
    25501 attaccattg ccaggaagag atttagtcgt tgttcaaaat gagggagaaa gattccagtt
    25561 ctttaaacca gataacatta cagatgttca agctatgaat aatatacata tggttgatgt
    25621 tagtgaccca acaaaaccaa cattaattgc tcaatttcca tatcctgaag ttccaaaaga
    25681 tttcccttat cctaacttta atgttgcggg attaggaaaa ccagggccat ttggcccaca
    25741 taatcttcat gaaccaatgg ataataagcc atggttagag caaagaggag atagagtata
    25801 ttgctgttat ttccatgcag ggctaagggt ttatgatgta tcagacccat attatatcaa
    25861 agagctagca tattttatac caccaaatcc aaataaaaca ccagaagaat cttatttccc
    25921 aggattccca ggaccacgct tggcagtaac agaagatctt atcgttgatg atagaggcta
    25981 catcatcata gatgctttag atgatggatt ctatatatta aaaatgaaag aagattaaat
    26041 aaatactaaa gagggagagt tgaaaatgaa aatactaggt atttcttttg gaacaaaaaa
    26101 tggaaataat gacacaatgt gtaaagttgc acttaaaggt gccaaagaag caggggctga
    26161 agtagaattt attcaaatgt catctattaa cattaaacat tgtactggat gttgtgcgtg
    26221 tgttaaaact ttattatctg ggaaaggtag tatgtgtgta ttaaaagatg attttgaatg
    26281 gttgcttgac aaaatgaaag atgcagatgg tatagtagtt tcagacccta tttttgaaga
    26341 aggggcatca ggattattcc atactataat ggaccgtttt ggacccagag cagatagagg
    26401 aaataacatt ataggaacaa aagttgcaga agctatagga ggaaaaattc cagattcaag
    26461 aatgcttaat gataaagtaa tatcatttat gggaatagga ggttctgact ggggtacaag
    26521 agttcaatgt gaacatgcta tgctagctct cataccaatg tggaaagtta tagataatgc
    26581 ttggttccca tgggcaaagg aattagtaat ggatgataca aggcttgttc aagttcatca
    26641 aattggttta aatatagttg aagcagcaaa agattttgaa aaagcttcat atcaaggaga
    26701 agaaggtgta tgtccacatt gccacaatag attattctac cttgagccag gtactaaaaa
    26761 ggcaatttgt gctctatgtg gtatagttgg agagttagat actataagtg gaaaaactat
    26821 atttagtttt ccagaagagc aattaggtca tgctcatgat actttaccag gtaagtttat
    26881 acatggtgat gatattaaga aaatggaagg tcattatgca gaagttcgta aaacacaaga
    26941 atttaaagaa agaaaaacat cttataattt tatagagcca ttaactaaag aaaagcaagc
    27001 tggagtttca ttaggataat aattaaaata ctaagactct tttttaaggg atgttagatg
    27061 ttataggagg cttattgtat gaatgaaaag ccaagtttta aacaaattga aattatttta
    27121 gcagttattt ttttggtact tacatattac aaggttagat taactccagc atttattgtt
    27181 atatttatac cactatattt aagttatttt gcagtatcta tgattgtaaa tcaaatagca
    27241 attaagctat tggagatagg gcaagctagg gaagctacta attacaatat aggaaatgga
    27301 tagaaagaaa aaagaaatat taacactgtc tatggggatt gctttactac ctcctttatg
    27361 ggcagtatta gcaccttata taggaataaa aactggagct gtagcactaa tctgtgcagg
    27421 attatatgta actaatggta ataaacaaaa agatggatta aaaataatgt ttggtttttg
    27481 gtgtggagat ttatgggcag tgttagccat tttaattatg ggatatatga atttcaatca
    27541 aaacctagaa ttatttttaa cacttagtat attaggtttt tttgcagttg taattgcatc
    27601 cttatttgaa aaaataattt tcctaccatc atggctttgt ggttgggcta taggtctaac
    27661 tattatgaca ggtgaaaata ttattaattt acaagatatt tgtattcaaa ttgctgtagc
    27721 tatggcagta ggagtatggt acgtgggtgc aggtgtagat ttgtttacaa tatatatttt
    27781 gagtaaagat aggaaaaagg gaaattgaaa gcatgtgaat atactttgat tataggagaa
    27841 tggctatggg ttttgaattt aaaataatga gaagtttaat atatgtagga cttgccaagg
    27901 aagaatatag acctaagcta atggactggt tatatcgtca ccatattcca gatagtatta
    27961 gcacttttgg accatattgt actaaatatg ccttttatca agcatatcct acaccaaatg
    28021 aaggtgagcg ttttggtgca cgtaagatgc aactaacaga acattattgg cttgtagatg
    28081 aacatatgcc tgagatggca aatagaatta tgacagaata tatgcctatg gatgttctac
    28141 gttggcaagg gtgtatacca gatgtagaaa ataaaagggt tcatgaaaat gcagaaagtg
    28201 gagatgcagg acgtgcagta ggtggagata atggatgtcc accatttata tttgcctttg
    28261 ttccaataaa ctgggaagaa gactttagag gaaaaggacg tactgtacaa gatggaccaa
    28321 actatcgttg gcaatttatg attaagtatc cagatggtat ctctaaagaa gaaggagaaa
    28381 aatggttcta tgatgaggta gtgccatact ttacaaactg ttgctatgtt aatcgttttg
    28441 tcagtagtaa aataatgatt aattatggag caactgcttt tgaccgtgta tcagaactat
    28501 ggtttgaagg ggaagaagaa tggtataaag ctgtggttga agagacaaag tcgtttatta
    28561 aaaaaccaga atgggcacaa gaagaggagt tcccatattt aaaaccacaa ttcaatatcg
    28621 catcagtatt cttaggtgat atagcaacta tggatgcata ctcacagtat cgtggatata
    28681 taccaatgag ataaaaatta tagtttgtga taagtagagg aggcatttac tcttactggt
    28741 agaagaagac ttattgtatc cttaaaagta ggtgaatata tagttttata tttaaattta
    28801 tataaaacta agactaataa atatgaaaca atagaattag aataatttga taatatttgt
    28861 taaaagagca tttagaatgt gtttaaagat taagatattc cttttatggt agcagatagt
    28921 tgaaataata aaactgttat catgaaagga atatttttat gtataggaaa tttttaaaaa
    28981 taaaagttaa atatgtttaa gaacatctta aagtgaaaga atcattgtta gaaatatgta
    29041 gacaatatag tctttataac gtatcatatt aacaagttta cacttggatt atgaaataaa
    29101 aagagtaatt ccaaaggttg taaatactat gctgactttg atacttcaaa gtttaggtga
    29161 ttttgtaatt ggtaatagaa atacgtttaa tgagcataaa gaatttatct aataatagga
    29221 gaatataatg tatacaattg gacaagtatc taaattttta ggaatatcta gagatacact
    29281 aaaattttat gaggacaaag gattagtaaa tcctaagaaa aatgatgaaa atggatatag
    29341 aatatataat caggttgata tctatgatat tgcaacaata aacttttata gagaaattga
    29401 tatagaaatt aaaaagattc aagaaataag aaaaagtaag agtataaaca atttagaact
    29461 cttactagaa gagaaggaac aaatcatact aaaagagata gaatataaaa agcttctctt
    29521 aaaaaaggtt cagttagtca aagaagattg tgacaaaata aaaacatatt ttggaaaata
    29581 cacaataaaa gaaatgaagc ctttggaagt aaaaggtaaa ataaaacatg ttactaacta
    29641 tgaggaatat gaagccctaa aagagaatac aaacaactta aaaaaagcag ttacattaac
    29701 tgatttaaga agagtaataa attttaatga agaaggtata atagaagaaa aatttataat
    29761 tgtaagggaa gtagatgact acaacaaaat catagaaggt gaagttctat ctcatcccaa
    29821 ttgtatttat actattattg aagatggcag atggtcaact ggaggagaaa atattgataa
    29881 taaagtggaa gacagattaa gagaaatagc aatagaaaat gaatgtgaat tacttggaat
    29941 agtctatgtt aatatattgc ttactactta tgaagaaggg attgagcgta tatttttaga
    30001 gatttatgca cctataaaat aatataaaag cattgacctg ggacttactc ataggtttaa
    30061 actcatgata taagcagtta taacttatat agcaattaaa tattaatttg aaatgaggat
    30121 tacttatgag aacagagaaa tcattaaaaa ggcctatagc cagttttatt attctaacaa
    30181 atataatttt tttaccactt tttttattgg tagtagtgac tataatgtta aaacttccaa
    30241 cagtgatatc tgacattgcg ttgtgtatat cagcgtggtc atccactttt gcatttatga
    30301 tattatttaa aaaaatttat ccaggtaaga aatttttagt acacgtaaaa gatagattta
    30361 gaaataaact taaattttca acagtatcta taataattag tatacaagtc ctaatagctg
    30421 tagtagttat atttatatta gcatctaaaa atcatggaat aatgcctaac tttacagttt
    30481 catcatgggg agcatttata tatttatttt taaaaaattt atttgcagga tcattaggtg
    30541 aggaattagg ttggagagga tttgttcaaa atcatcttca gaaaagacat tctcctttaa
    30601 aagcatccat aatagtaggt ttttggtggg ggatgtggca tttaccaata tggtttacaa
    30661 caggattcaa agggcttgat ttaataaaat atattatatt ttttatgatt gcaattatat
    30721 caatcagtat tataatgaca actttttata atctaaataa aactttgata atacctattg
    30781 taatacatca actatttaat tttttaatag ggataattaa tggagattta atagagctta
    30841 taaattacta tgcaatgtta tatttaatat ttgcaattgc attaatagtt ataaatccag
    30901 gaaatgtatt atataaaaat attagagagt aatatatatc tttatggtaa gatataaaga
    30961 aattattaga agaacatcca aggaggaata aacatggttt tactgattgt tgatgcacaa
    31021 aagttaataa caaacgagag gttatataaa tttaatgaat ttgtagtaaa tgtagaaaat
    31081 ttaattgata cagctagaaa aaataatata gaagtaatat atgtacgtca tgatgatgga
    31141 gttgaaaatg aattgactaa aggtaaaaat ggctttgaaa tatacgaaaa atttaaacca
    31201 tgtaatggag aaaaaatatt tgataaaaaa gtaaatagtg cttttaaaga aactggtcta
    31261 ttagaatacc taacaaataa tggtgaaaaa gatattatta ttgctggtct ccaaacagat
    31321 tattgtattg atgccactat aaaatgtgga tttgaacatg gatttaatat aatagttcca
    31381 gcttattcaa atacaactgt tgacaatttt tttatgtcag cagaacaatc atataaatac
    31441 tacaatgaat ttatatggaa tgaaagatat gcgaagtgta tttcattaga ggaaacactt
    31501 agaaaaatga aataaaaata gagtatgaat tgtatatgta cataagttga tttcataaaa
    31561 aaggatgtta aattccaagt taaaaattag attaaatata ttatattata gataaggcac
    31621 atcaatttta ttttaaatta atgtgctttt taattgtagt aatttattta taatcaatat
    31681 gatttttatt atttaaatca atttctcttg agtttctttg tctaaagaaa ctttttttat
    31741 ttataaaatc tacagttata ttatagtatc tattttagag aagtttaatt tttgtatcaa
    31801 tctaaaacaa aagttatact taaatgaaat tgaaaacgat aaaattctca aataaaataa
    31861 gtattgtgga ggtgatgaaa gaatccaatg ataatatgaa gactaatctt aataagaaag
    31921 taggggttaa tggtagtgga caaagaaatt gtatcaattc tccagatttt attaaatagc
    31981 acattgatta caactaatgg attacaagag gagtctaatt catcaaagag acaaattact
    32041 tatagaataa ataaaatcaa tgacatgctt aaagtaaaaa atgtaccact tatatgttta
    32101 agagctgata aagatattat cgttagaaaa gaaacaaaaa aagcaattaa agaaatttta
    32161 gaaaaaaact attctaagaa tacttattat tttagtaaga cagaaagact tttatatatg
    32221 tatttaatgc tttttattaa catggaggat atttcaatta atcattttat aaattctata
    32281 aaagtaagta ggtctactgt aaatcttgat ttcaaggatt tgataccaga gcttgaaaag
    32341 aagaacatta aagttaagaa caatcgtata aatggatatt acatagttgg caatgagatg
    32401 gaaattagga gagtgcttat taaaaacatt atagaaactt tgtctaatga gaaaagttca
    32461 agagtatttg atatttttat taaagaatat aatttagata gttttgaaga ggctaaaaaa
    32521 attatattaa agctaataaa aaaatatgaa attacttttg ttgaagatag attagtagaa
    32581 tttatatata tatttatctt tctaaaggca aggatgtatt caactagaat agttactcag
    32641 gaaaatgtag atattcctaa tatttcggtt atgagttcaa tgaaggagta taaatttgct
    32701 aaggaattat tagaagtata tgggagtgaa gataagataa agcctcacaa tataatgtat
    32761 attagtgctt ggattttagg tatatcagta ggaaattatg aagaagatac agaagataag
    32821 gatgtaattt caaaaattgt aaataaaatg atgacaaagt ttggatattt aagcggagtt
    32881 tactatataa gccaagaaaa aatatttaaa caattatatt ctcattttag acctgcctac
    32941 tatagacttt tatttaaatt acctatttat aatccgattt gtgaaaaagt aaaagaagaa
    33001 tataaattag tttatagaat tgtaagtaat gcaatgaaag agttttgcgg attatttgga
    33061 gaagaaattc aggaagaaga gttagcatat cttacaatgc actttgcaac acttttttca
    33121 aataaaaaag aatttgatgg ttttagaaaa agaatagcat taatagtttg ttcaaatggc
    33181 gttggtagtt cagctatttt gcatgcagaa cttacaaact tatttcctga cttacacttt
    33241 ataccaatgt cggaatcagt tggattagaa aatataagtg aacctgtaga tattgtattt
    33301 actactaatt ataacgcaga gggtttaaaa acagatgtac cagtaattaa agtaagccct
    33361 gttatgacca caaaagaaaa atataagatt acacgtgaag tgtatattca attaggtgat
    33421 atttttttaa gacaacctaa aatagatgag gttatggata taataaaaaa atatgcaaat
    33481 gtaacctctg aaagtattct ttcaagtgag ctattagctt attttacaca gatagagaat
    33541 tttacatcta aggaaggaga ggggcctatg ctaagtgaga ttactaatga aacactagta
    33601 aaaataaagg taaaagctaa gaattgggag gaagctatta gacagtcagc ttctgtatta
    33661 gttgaaaata acaaagtaac tgaagggtat gtagatgcta tgattaactc agcaaaagca
    33721 tctggaccat acatagtaat tacaaaacat gttgcacttc cacatgctag accagaagct
    33781 gggtcaaaag agattgcaat aggcattgct actttagata gtcctattga gtttgggaat
    33841 aacgaaaacg accctgtaaa atatgtattt tgtctaagtg caatagacaa taatagccat
    33901 ttacgtgcta tgtctgagct agttgaacta ttggaagaag atgagttttt taaggtttta
    33961 gatagtgcta aagaagctaa agaaattatt gattttataa aaacacacga attataaagg
    34021 aggatttaat tatgtataaa attttaatcg catgtagagc aggagttggc tcaagtttaa
    34081 tgttaaaaat aaagactcaa caaattatta aggaaaataa ctttccaatt gaagtagagc
    34141 atggttcatt ggattcacta aatggattca atggagatgc tgtagaaaca ttaattgatg
    34201 ttgctgaaga attaaaaaat aaaaatttga agtttgatat aattgggatt cacaatattg
    34261 ttgaccgtaa tgaaataaag acagcactag aaaaattcct tgcttcaaaa gagggataaa
    34321 tttaagatga taaggaggaa tatttatgga gtttattatt agtttgctga gtacacctgc
    34381 tgttttgctt ggcgtagttg catgtatagg attgattctt caaaagaaat cagctgttga
    34441 agtatttaca ggctcttcaa aaacacttat cggttttttg atatttggta ttggtgcctc
    34501 tgctatgaca ggagcacttc aaaatttcaa taaactgttc caacatggct ttggaattac
    34561 tggtgttata gcttcaccag aagcagctac agcacttgca caaggtacat atggttttgc
    34621 agtttcatgt acattaattc ttggattcat attaaattta gtatttgcac gtattacaaa
    34681 gtttaagaat attttcttta caacaggtca tagtttgttc ttttcttgtg tattagtttt
    34741 aattatgaaa gcacatggat ttgataatac aatcactatt ttaataggag gaactatctt
    34801 agggtttatg tctgctgcac tacctcaatt ctgtcaacca tttatgcgtg aattaacagg
    34861 tggcgacgaa caagctattg gtcactttaa catgattggt tatggtttat caggttatat
    34921 tgggcgttta ttttcaaaac ataaagatga tacaacagag actatagaat ttcctaagtg
    34981 gttatcaata ttcagagact tcttaatggg tctatccata gttatgttaa tcttatttta
    35041 tattgcaaca ttaaaagctg gtcaagcatt tactcaagaa attgctggtt caacacattg
    35101 gttggttttt ccgcttatag aggcatttac atttgtggca ggtatgtcaa tattgatgtc
    35161 aggtgttcgt atgttcttag ctgaaataac tgcagcattt gtaatcattt cagaaaagta
    35221 tattccaggt tcacgtcctg cgctagatgt tccaacagta tttccatatg caccaaatgc
    35281 agttattatt gggtttatat cagcatatgc tgctggtcta ttagcaattg ctattatggc
    35341 atcatttcct agtatatttc ctgtagtaat tattccagct gctcacatat gttttttctc
    35401 aggaggtaca gctgcaatat ttggcaatac ttcaggagga tggagagggg ctattgctgg
    35461 gtcatttgtt gtggggttat tacttgcatt tttaccagtt atactatatc cagtttatgg
    35521 gactcttggt atagaaggag caactttccc taatattgat tacaatgtag ttggttcgat
    35581 attacataat attttacaat ttataaaacc tatttaaact aaattatata aaagtatagt
    35641 catagttact atgatttcaa ggaggataca tcttatggaa aatacattat ctgaattttt
    35701 agataatata tctaatgaat tgtcagaatt tattgcctca atagatgaga catctataaa
    35761 taaagcatgc gaattaattc ttgaagctga aaaaaatcac ggacgtgtac atgtgactgg
    35821 tattggcaaa ccaggacatg tatcgggata tatttcatca ttgctttcat ctactggaac
    35881 gtcagcatat atattgcatg gtacagaagc agtacatggg tcaagtggtc aagtagttga
    35941 aggagatgtt gttattgcaa tatcaaatag tggtgaaact caagagttaa aagcaactct
    36001 taagattcta aaagtaaatg gagcaaagat aattggtgta agtggtaatg agagttcatt
    36061 tttaaaaaat atttctgata tattcctgtt tgcaggtgtt aagcaggaag gagattgtct
    36121 taataaagct cctcgtgctt caattttagc tgaaacaata atattacaat cattaagtgt
    36181 tgtattacaa tatgctaaag gtcttaatac acagcagtat ttgaagtggc atccagcagg
    36241 aagtcttgga aagtctatta gagagggaat ataattttat gaaatataaa gggattatat
    36301 gtgcaatgat aacaccattt gatgaaaatc aaaatattaa ttcacaagca acatgtcaat
    36361 taattgatta tttgattgaa aagggaattt atggattatt tattttgggc actaatggtg
    36421 aatgtcatgt attaacagat gatgaaaaag ttgaatttgc aaagattgtt attaatcata
    36481 caaataatcg tgtacctgtt tttgttggaa cagggggtaa ttcaactcgt gaagttgtag
    36541 atttatctaa gagaatggaa gcgattggag caagtgcatt atctattatt acaccatact
    36601 ttgttacacc aacacaacag gaattaatct tacattacaa aactattgct aattcagtta
    36661 atttacctat tataatgtac aatatgccag gtaagactgg aattaatatt gaaccagagt
    36721 cagtacgtga attatcaaag ataaagaata ttgttggaat taaggatagt agtggtaaac
    36781 ttgacaacat gaaagcttat attgaagcaa cgaagaatga gaattttagt gtgttttcag
    36841 gctcagattc acttattctg gatagtctaa aagctggtag tcaaggagct gttgcagcaa
    36901 caacaaactt cctcacagag attggtatct ctatctatga aaactttatg aaaggggatt
    36961 tggaagaagc tcaaaaagct caaagtagta tagaagaact tcgacgtata ctgaaacttg
    37021 gaacaattcc atctgttatg aagaaaacta ttgtcttgaa tggaattaat gttggaactg
    37081 cacgacttcc tgtaactgaa ccaactgggg aagtacttga agaaattaaa cgagtagttg
    37141 aaaattatag gacaatactt aataaaagta gtgagaatag ataatataaa tagggaaatt
    37201 acactggtat ataattaata tatatattat aaaacatgac taaaattaat gaataagtaa
    37261 agtggtttga tgagtataga ggtgataata tgaaaaagat gaatataacc aaaagaatgt
    37321 cagaatgtgg ggctcttgca attgtaagag aagaaaatct taaccgtgca tgtgaaattg
    37381 ctgaaggatg tataaaaggt ggtataacag ttatagaaat gagttatacc ctaaataatg
    37441 ctggagaaat aattcaaggg cttaataaaa agtatggtga aacactttgt gtgggagcag
    37501 gaacagtttt ggatagtgaa acagctcgtc atgctatatt acatggagct caatttatta
    37561 ttgcaccaaa ttacaatgaa ggtgtagcga agatttgcaa tagatatcag attccttatg
    37621 ctccaggatg tacatcattg actgaggcag tagatgcact aagtttagga gcaactttta
    37681 taaaagcttt cccaatatca gatttctatg gacctaaact agtaaaggta tttaagacac
    37741 caatacctga tatgccagtt ttagcaagtg gagggattaa tattgaaaac ctacatatat
    37801 ggttagaaaa tggagttgat gtatgtggat ttggtggttt attaactaaa ggttctgttg
    37861 aagatattgc taaaaatgct aacaagattc gtgaaatcat taaaaatata agaaaaattt
    37921 aacatagggc tgtatcatag tatcttataa ttactatgat acagcctttt taatattatt
    37981 caaatttaaa acagtttaca tttatattat attaaatata atttcagtaa ttttatatta
    38041 atttttctat ctggaaaaaa atgatttaaa acttaagtta tgatataatt tcattaaaag
    38101 aaggcgattt ttagtaaata tgagaaaata atgtgttttt aggggaaaag ttaaatacag
    38161 atttaagtga acaagaatcg ataattaaga tattaaatgg tgaatagggc atcaaaaaaa
    38221 ttactaaatt aaaagtttta gagggagaat cttagcaagt gtgtgtgaaa attcaatttc
    38281 aaacaaaaaa taattgtaaa tgaaatcaat ttatacacgt tgaagattca cttttatcat
    38341 tatattaaaa agcagagtga attaaaagtg agtctaaaga taggaggata attaaaacaa
    38401 tgaaagaaga cattaggtta catcgaatgt gtaaaaaaga acaagcaaca aagaatgaag
    38461 ttatatcaga ggatattcta aaatctatga gtattggggt cagtaaacat tttttagatg
    38521 attcatttac aataatatgg ggaaatacat cattctatca attattagga tatacagaag
    38581 aagaattttt agttaaattt tctagtttaa aagattatta tgaacagaat ctttatcatt
    38641 ttgaatctat gaaaaatcat tttttagagg cttatcatca tggcgaaaag agtatagaat
    38701 atcaaatttg catttcagca aataatggag accctgtttg ggtaataatg actggtatat
    38761 taattgaatc acaagataat gagaaatcaa tggtctatat attgtattca aaaattaatg
    38821 agttaaaaat aaagcaagaa gaactatctg atatggaaaa agagagtaca gagaatttta
    38881 aatggatgat gtcagagtat gctgggaatg tttatattag cgatatggat acatatgaat
    38941 tactatactt aaataagcac tcatgcaata ctttacaggc atcagcaaat gaacttattg
    39001 gaagaaaatg ttatgaggta attcaaggta gaacttcgcc atgtccgttt tgtacaaatt
    39061 cgtatttaaa aaaagatgac atatatgaat gggaatttta taataaaaaa ctgaaacgaa
    39121 catttataat taaagaccgt atgttgaatt ggcaagggcg aagagttcgt attgaattat
    39181 cttatgatat gtatagtgct gaatataaat tagcaaaaaa agatcaggaa agagaatcaa
    39241 ttttgaaaac tattccagca ggaatggtta gattagatgc aagagattat cttactatac
    39301 tttggtgtaa tgatatattt ttgaatatga ttgaatatac aaaggaacag tttgcagagg
    39361 aacttaataa tcaatgtgga tatttatttt ctgaagatta taaacgtagt aagaaactgg
    39421 cacaagattt gaaggagtct ggggataatg ttgtatttga agcaaaaata tatacacgtt
    39481 caagggaaga acgtatatgg actgttacat tgtgttatat cagtggggaa gacagttggg
    39541 atggaatacc atctttttat agtataggta ttgacataac aaaggaaaga aaacagattg
    39601 agaaattaca gcatatatca gagaaagatg cattaacagg aatttataat cgtgctgaga
    39661 ctgaaaggca gattaagaaa tattttgaaa aaaatttaaa tgttatgggt gcactgttta
    39721 tgattgatac agataatttt aaacagatta atgatacaga agggcatatg attggagata
    39781 tagtacttac tgagatggca tcaggtatga aaaaaataat gcgtgacagt gatgttgttg
    39841 gaagaatagg tggagatgag tttacaattt ttatgaagaa tatttcttca gttaaagatg
    39901 cagaaaagaa agcagaagaa ctattgtata tgttccgtca tctatttcag aaagaaaaaa
    39961 gttttctaaa agtaacttgc agcataggaa tagctatata tccaaaggat ggtactacat
    40021 tcaaggaaat atatgcaaga gctgataaag cactatatca agcaaaaaat atgggaaaaa
    40081 ataattatgt aatctacaac caagattatt ttaaagaatt agaagaattt gattgttctt
    40141 ctcttggtac agttattgat tcagaaaaac aatatgctga atgtcctgat aatcttacac
    40201 gttatatatt ccgtatgctt tatcagactg atgatataga ccaggcgatt aatatgatac
    40261 ttgaggttgt tgggaaacag tttgatgtaa gtcgtgttta tatttttgaa aatacagaag
    40321 atggtcgata tacttctaat acttatgaat ggtgtaatga aggaatctct tctcaaatgg
    40381 cttatttgca aaaccgcaat tatcaagact atgaggatta tgaaaagttt tttgaggatg
    40441 aatcagtttt ttattgtcga gatatccaca cattaagtcc taaactagaa gaattgtttt
    40501 ctagtcaagg tatccactct acacttcaat gtgcatataa agaagataga gttttcagtg
    40561 gatttgttgg atttgatgaa tgcacaggac tacgtctatg gtcacaagag gaaataagta
    40621 cattatcatt gatttctcaa attatatcaa tgtttttaca acgtaaaaaa aataataaac
    40681 ttaatcaaca gattcaacaa taccagaata ttttagataa tattgaccag tgtatttgtg
    40741 tgattaataa agaaaataat tttttattat atgtaaataa aaaatttaaa aatacatatt
    40801 ctaaattcca aattggacaa ccttattatc ttgattctat agatattcat aagatatcca
    40861 ttatatggaa taaaaaagaa gcatacctat gtactagcat gatttaatgg taaagtaaag
    40921 tttatattgg acttaaatta aatttcgttt taaataagat attattttag ttgattactg
    40981 aaaagactag aatctatatt aatgaattat actaatttta taccactatt aaaatattgt
    41041 ttgctaaaaa taaaaaatag ccttaaaaca gttgattata aaaaattaac tgctttaagg
    41101 ctatttttat ctttgtgacg aaatagacac ttgccattta gaatgtgaca atatagtagt
    41161 tgtttagaaa aggcacaaag cattatactt taactaaagt aaaatgtatt ttgcttttag
    41221 aataaaaaca attaggaggg agctataatt gaaaaagata atatatgtat tatttacaat
    41281 tgaactatta atagtatctt tattaggtct aaatatagtt aaagataatg aaattaataa
    41341 tattttatat aacgatacaa caagtatatc tgtaatgttt aaagattata aaaagttaaa
    41401 taaaaattat agtaagtgga ttaaagatat tgcagatgaa aataatgtga ctatatcaaa
    41461 gtatgttttt aataataatg aaaaattatc tatatatacg actgatacaa gtttgaataa
    41521 caatataaag ttaaaatcag gaaaatttcc taatactaat tcaaatgaat ttattagtaa
    41581 tataaacact aataatagta atcaagtagg taaattctca actatgagta aagacatatc
    41641 aattttaatt agggattttg gtaaaataag tgaagttgga gaatcaggaa tcttatatat
    41701 ttcaactcaa aatgaagata caataaataa aatattaaga gaactaaatg tagatagaag
    41761 tatttttgta gcaagattac atgatagata tgttaactca aatttatact taaatccttc
    41821 aataattaga gatttaatac taattatcct ttgtttcttg gctacaataa tacattattc
    41881 aattagtgtg agtagagagg cttctatttt aagattaaat ggatactcta agctagatat
    41941 aattgctaga gttataaaaa atatacttag aattatgatt ttatcatctg tcacagcatt
    42001 attaatatat ataatctata ttttaaaatt aaatataggt gttagagcat gcttatactt
    42061 tgctatgttt tcgattatat gtattttgat aaatattttg atatctatat taatagttgg
    42121 ttttaatagt agaagttcta aatatgtgct atctctaaat ggaaaaaaat cttatggttt
    42181 tgtaaatata atgcatttca cattgaaaat tgtatttgta tcatttctta tattatccat
    42241 aaataactgt attttaaatt ataatatgct acaaactcag ttaggaaatc tatctgagtg
    42301 ggataaagca aaaaatgttt ataatcttac tcttaaagat acaggcgaac aatctttagg
    42361 aaaggaagaa gtaattaaaa atgccaagat taaaggtttc tataaaaatt tggtagaaga
    42421 aaaagatgct ttcttaatag attcaactaa ttttgaaaaa cttgaagatg gaagttacat
    42481 gtatgaaata aattcaaagg gtaaaaaccc agaagtaagt caatatggta aaaatataaa
    42541 aataaataaa aactatctta aagttaaccc tatttactca aatggcaaag aaatatttaa
    42601 tctaatcgat tatgacgata agactataaa tttattagtt cctaaaaagt tacaagtaca
    42661 tgaaaatgag attaaaaaag agtttagaga attattttat tttgaaaaaa tagaagtaga
    42721 aaatatgtac aataaagagt taaatagaga gttaaataaa acaaagaagt cagatttaaa
    42781 tgttaatata atatatgtag ataataatca aagctatttt acttataact cccttgttat
    42841 ggatgacaat aggaatctca ttgatgaccc aatagcaata gttgacatag ataatattga
    42901 tgattctttt tatctttctt atatatctag atgtgtatat tttaattcta agaaattaga
    42961 tgcccttgca gatataagta gcattattga agctcaaggt gtagaagcgc atatccaaag
    43021 tttacatgct gtttataatg agtatggttt agaaataaat aaactagaaa aatatttgaa
    43081 tagtgaaatt tttactataa taataatagc aatatcaaac ttaatgatta cctacaatat
    43141 agtagctagc tactatgaaa gaaataaata taagttatat attaaaaaaa tatttggtta
    43201 ttcaactaca gctagaagta tgttgttaat agtctcatta atattaacaa acattattcc
    43261 aataggcatt atatcaacaa gagtagattt aagtaataat attatcttat ttggactttt
    43321 gatattagtt atagaagtaa ttgtatctat tgtattagac aagattatct caaatagttc
    43381 atttaataaa attataaaag gagaacatta aaaagatgat ttcattaata aatatatcta
    43441 aaaaatttaa agataaatct ataatagaca aatttaacct agaaatttct aagggcgagt
    43501 ttgtagcgat aacaggaaat agtggttcag gtaagacaac tttacttaat ataatgggat
    43561 tattagaaaa acctaattct ggtgatatta taataaataa tataaaaaat ccaaatagta
    43621 aacagataag aattttacaa agggattttt atggctatct atttcaaaat tatgctttaa
    43681 ttgagaatga aaatgttgaa aataacttga aaattgcttt aaagtatcaa aaaaatatca
    43741 accataatga aaaaataaat tacgcacttg agtctgtagg tcttagaaaa tacaataaaa
    43801 aaaagatata cgaattgagt ggaggagaac aacaaagggt agcattagca agagtaatat
    43861 taaaagaatg tgaagtaata tttgcagatg aacctacagg taatttagat aaaaaaaata
    43921 gagacatagt atttgatata cttaaaagcc taaataagaa tggtaaaact atcgtatttg
    43981 taactcatga tttagagtta tcggagcagg cagatagagt tataaaattg taataatatc
    44041 aactataata aatataagaa agagattaca gctaaatcaa gtttaataat aatacgaata
    44101 gaatttaaac attaagtaaa ttagtagttt gtaaatataa gtataatatg atatcataaa
    44161 ggctcaaaag aaattttata taataagaaa tctaaaaata acaaatggag gacatataaa
    44221 gatggaaaat ttaccaaatt gcccgaaatg taattcagaa tatacttatg aagatggaac
    44281 tcttttagtt tgtccagaat gctctcatga gtgggcatta ggattgggag ctgaagaaga
    44341 ttcaaatatt atcaaagatg taaatggaaa tgtattaaat gatggagatt ctgttacagt
    44401 aattagagac cttaaagtaa aaggaagttc atcatctata aagattggaa caaaagtgaa
    44461 aaatatccgt ttaatccatg actcatcaga tggacatgat atagaatgta agatagatgg
    44521 ttttggagct atgaagctaa agtcttctgt tgttaaaaaa gcgtaatatt ataaataagc
    44581 tgtagtgttt attgtttttc agtacagtat aaaaccataa gaatctatta agtaataaaa
    44641 gtttgtttat ttgtctttat attttcttat ggttttatta aatataaatt ttattgaaca
    44701 ccaaaatatt ctctcctcta caaataagcc aatcttattt aaactaatat actttgtact
    44761 atttatactg aaattgtaaa tttaaatgct atgttattta ggtttgtata gttaatttat
    44821 atatttctga ttttataaat tgtatttatt attatatctt gattctaaaa tcattaaaaa
    44881 tttcaacttc tataaagatt tacaatttat caaatacatt atgagtatat aaacaattta
    44941 ttattacagt gctacattta aaataagtct tagtataaag gtattgttac aagtataaag
    45001 aaacttatgt atgctattgg aataaataat accttaaatt ataattaaga ataagaactg
    45061 ttaaataagg gacttgatta tcatttagtt atagataata taatattaaa aataaagttt
    45121 aagaggagaa aaaatatgat agatatacat aaaaatatat atgataataa gttatttgag
    45181 gagctaaaga ttgactgtaa gaagtgcttt ggactttgct gtgtagctct ttatttttct
    45241 gcttcagatg gatttcctat cgataaggaa tcaggaaaac cttgtattaa tttacaacca
    45301 gattttaaat gttctgtaca taatagtctt atgaagcgag gttttaaagg gtgtactgca
    45361 tatgattgtt ttggttcagg tcaaaaagta gcacaagtaa catataaggg gatagactgg
    45421 atgcaatcac cagaactaac aaatcaaatg tctgaagtgt ttttaattat gagacaatta
    45481 catgaaatgt tatggtatct taaagaagca tctgtattaa atatatcaga tacaatcaaa
    45541 tcaaaaattg atttaataat tgaagaaact gaaaagataa ctaatatggg cccagaacag
    45601 ataattaatt tggatatcat atcacataga acaaaggtta atttattatt atcacaagcg
    45661 agtgagtctg tgatgggaaa ggttaaatca tttatcaaga cttctactct taaaaacatg
    45721 aaaaaattaa gtaaaaatat agatttaata ggagcagacc ttagaaaaat aaatctaata
    45781 ggagcagatt taagaggtag atttctaata gcagcaaatt taagaaatac agatttgagt
    45841 ggggcaaatt taataggagc agacttaaga gattgtgata ttagaggtgc taatcttgaa
    45901 aatagtatat ttttaacaca attacaagta aatactgcaa aaggagattc tagtacgaag
    45961 ttaccagctt cactaatacg ccctaaatac tgggaaaaat aattaaatta atacataatt
    46021 ttacaaaata taaacttttt tgactttagt tcatattata cattagagat tctttacaag
    46081 aatttcttaa tataatatag ggagagatat aaaaatgagt tatcaaaatt ataaatgtga
    46141 aagagattat gtgtatgatg attataaata caataagtgc aacaagtgct ataatgatta
    46201 tgaggaaatg acacatgttc atgaatattc agaaagtgtt aagttagcag aagaatgtga
    46261 ggatagacat aaccaccgtg cagcaggggt tactggtgaa gctataccaa taaatgtagg
    46321 tacaaatcat gttcataaaa taaatgataa tgtagatttc cttgaccatt tccataagat
    46381 atgtgttaca acagggccag caattagaat acctggaact gataaacaca ttcacttaat
    46441 atgtggagaa actactgtta atgatggtca ttgtcataaa ttccttttta ctactcaaat
    46501 agaagcacct ttagtataag ctgatgtgaa ttattgtagt gaatttgcta gattatagta
    46561 taatatataa tagataatat ttaaacttaa tgaggactat gatatttaac cttcgtagtc
    46621 ctttctaagt tttgtataaa aaagtgttat gcaattaaaa gtgatatagg gaggaaattt
    46681 ttatgaaatc tggaataatt cttgaaatga aacaaataaa ttcaatagaa tatgacgaaa
    46741 tgttgcaagt ctgggaatca tcagtaagag caacgcatga ttttttaaca gaaaaagata
    46801 ttgaatcttt gataccatta gttgagattg gacttaaaga agtagaaaat atagtttgta
    46861 taaaagataa tgatataata aagggcttta taggaataga taaagataaa attgagatgc
    46921 tctttataga agataaatat agaggaaatg gtattggtaa aaaattaata aaatatgcta
    46981 tagataaata caatgtaaaa tatgttgatg taaatgagca gaataaaaaa gctgtaggat
    47041 tttatattca cttaggattt aaagtgtttg ataggtctga aatagatgga caaggtaacc
    47101 catttccaat actacatatg aaattaattt aaagttataa ttctcactta ttcgcaaaaa
    47161 tatttactta aatttttata caaataaaag tcgtgacagt cttaggacac gactttttta
    47221 ctacactatt aaattgaaat ttatctgttc tatattatga ttattagatg tagttttttt
    47281 attttaacta tgtacttaaa taccaagtat acccatacct atcaagtact tcagcagcgc
    47341 catcattttg atgtggtggt gggtgtggta aaaattcttg tacaagtgta ccaccttcgg
    47401 caagttttac agatatttct tctatcgctt ctcgagatgg tagaacaaca caaatcgcca
    47461 tgccagaaat tacaacaggc ttgtctgtat ccgctcccat tatacaacct tcgtattttg
    47521 tgaaagtaac acttgcgtgc ataataggat tgtttggatt gctgtctaat cgcgcaaata
    47581 tagtttttcc tcctccgaaa gcctcagcat aaaaattaaa tgctttttca caagtaccat
    47641 taaatattaa atatggagtt agcatgacca atatatcctc cttgatatag aataatttat
    47701 agttgcacct gataatctaa attatgattt agtaaattgt atcataggga aaccttgaag
    47761 tatataattt tttattatta tattatacaa atttattaat ttaaaaaaat gttatatgta
    47821 cggaaggttt acaggataaa atataataaa aagattaagg tgacattata aaaaatgtat
    47881 attgacattg acgctacgta attgtatata ctttgtctta aaggagatgg taaatatgaa
    47941 tattatagaa attcgctcag ataaaatata caagaagata atggatgcgc caataaacaa
    48001 aaaagaagat atatacagat atgaattaat gaagcctttt gaatttaagt ggaagtgtat
    48061 gaatgttcca atagttgcta gacagaaagg tggatatgat gtaattatag caagtgaaat
    48121 gttaggggtt ttatcgccta aggatattga tgaaaagcaa aaaaagaata taaatgtgtt
    48181 atctgctgat aaaatttggg gcacttgcaa agaaaccata gaaaactcta taaatgcttt
    48241 tataaaagaa gggtatgatt taaacattaa ggactataaa tattcaatat tattggcgaa
    48301 tccaaatagt ccttatacaa tattaagtga tggatactgg ggtgatggtg ggattcctgg
    48361 atatatattt ctatcattgg ttcctaatga atatactatc aatagattac cagtattaat
    48421 agcacatgaa tgtaatcaca atattagatt tcagtttata gagtggaata ataatataac
    48481 attagaagaa atgatgataa atgaaggtct tgcagaaaat tttgcaacat ggatgtttgg
    48541 agaggaaatg ttaggacctt gggtcagtag aacagatatc gaaacattaa atacttatat
    48601 aaagccaata ataaaaagtg ctttaaaaga aactggattt caaaatataa catcttatct
    48661 ttatggtgat gatatagcta aaatgcaagg atattttcca gtagggttgc cttattgtgc
    48721 aggatatgct tgtggatatt atatgattaa gtattattta gaaaagacaa ataaatcaat
    48781 aatcgaagcg actttattgc cttatagtga gataatcgaa gcagtaaaag agttttggga
    48841 ataaatttta taaattgcat aatttgaaat aaattatgca attattttat ttttaagaaa
    48901 aaataaattg acaataattt ataagaaata tacaataata tatataaaga aatatttcaa
    48961 tatttaaaag ttttaagatt tcatatctag agtagctaac attacatgtt agtttcttgt
    49021 tacttatcta attactttat atttcgtagt tatacataaa attactataa aaaatgaaat
    49081 atattaaaca atcaactgaa aaatgaaatg
//
LOCUS       DAEQAF010000234        26094 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.guided.050, whole genome shotgun sequence.
ACCESSION   DAEQAF010000234 DAEQAF010000000
VERSION     DAEQAF010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26094
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.guided.050"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            247..864
                     /locus_tag="KRN00_003727"
     CDS             247..864
                     /locus_tag="KRN00_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBH1829499.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTTDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            972..3503
                     /locus_tag="KRN00_003728"
     CDS             972..3503
                     /locus_tag="KRN00_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBH1829500.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLHSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNIKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3937..4638
                     /locus_tag="KRN00_003729"
     CDS             3937..4638
                     /locus_tag="KRN00_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBH1829501.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4688..5761
                     /locus_tag="KRN00_003730"
     CDS             4688..5761
                     /locus_tag="KRN00_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBH1829502.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFMNHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIITFKVIIPIV"
     gene            6031..7131
                     /gene="vanG"
                     /locus_tag="KRN00_003731"
     CDS             6031..7131
                     /gene="vanG"
                     /locus_tag="KRN00_003731"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBH1829503.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPILHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7128..7934
                     /locus_tag="KRN00_003732"
     CDS             7128..7934
                     /locus_tag="KRN00_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBH1829504.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7952..10090
                     /gene="vanT"
                     /locus_tag="KRN00_003733"
     CDS             7952..10090
                     /gene="vanT"
                     /locus_tag="KRN00_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBH1829505.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFMLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKKLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIAFIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKVFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10404..11024
                     /locus_tag="KRN00_003734"
     CDS             10404..11024
                     /locus_tag="KRN00_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBH1829506.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11190..11726)
                     /locus_tag="KRN00_003735"
     CDS             complement(11190..11726)
                     /locus_tag="KRN00_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBH1829507.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11839..12513)
                     /locus_tag="KRN00_003736"
     CDS             complement(11839..12513)
                     /locus_tag="KRN00_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBH1829508.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12716..14590
                     /gene="asnB"
                     /locus_tag="KRN00_003737"
     CDS             12716..14590
                     /gene="asnB"
                     /locus_tag="KRN00_003737"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBH1829509.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNNLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSAGFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWYQLFIEHKNVEY
                     "
     gene            complement(14682..16118)
                     /locus_tag="KRN00_003738"
     CDS             complement(14682..16118)
                     /locus_tag="KRN00_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBH1829510.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKRSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYNSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWM
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVDRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESNLVKIFANNFIEIVN"
     gene            16447..17025
                     /locus_tag="KRN00_003739"
     CDS             16447..17025
                     /locus_tag="KRN00_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1829511.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            17064..17642
                     /locus_tag="KRN00_003740"
     CDS             17064..17642
                     /locus_tag="KRN00_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1829512.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            17728..18357
                     /locus_tag="KRN00_003741"
     CDS             17728..18357
                     /locus_tag="KRN00_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBH1829513.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            18347..21106
                     /locus_tag="KRN00_003742"
     CDS             18347..21106
                     /locus_tag="KRN00_003742"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBH1829514.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            21193..22755
                     /locus_tag="KRN00_003743"
     CDS             21193..22755
                     /locus_tag="KRN00_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBH1829515.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            22756..23892
                     /locus_tag="KRN00_003744"
     CDS             22756..23892
                     /locus_tag="KRN00_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBH1829516.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            23956..25032
                     /locus_tag="KRN00_003745"
     CDS             23956..25032
                     /locus_tag="KRN00_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBH1829517.1"
                     /translation="MKYFDYICKDDLERIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNSHSITGILIPKVNSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            25010..>26094
                     /locus_tag="KRN00_003746"
     CDS             25010..>26094
                     /locus_tag="KRN00_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBH1829518.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWISDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMDSKESLKKEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIG"
BASE COUNT        10139 a         2769 c         4566 g         8620 t
ORIGIN      
        1 tcaaaatgaa ctttttagtt catgaggcac tctttttgta cgaaataaaa tatattttta
       61 ttatttcaac aatgaaaaag atgcttgttt ccattttgag acagtataat ttttatgtaa
      121 ctttaatttt agtaaatata aagttttaaa attgataaaa taggaggaat ttttaatata
      181 aaagggtaaa taaagggttt agagggcata atatagaata aattaatata tttaaggagg
      241 gtttttatgt gtaaaaaaac gtatttatta gtggtaagta tgcttatagc gggtttatta
      301 actgcatgta gtgggagtcc aactacggat tcaggacaag cacaagataa tacaaaaaag
      361 gaggcaaatg catcaaataa cgctttaaaa gatgaaaaaa ataatgaaaa tttaatggaa
      421 caagatttta aagtgccata cacagatgca ataaacatat ttaaagataa atataaggat
      481 gctgatatag tagatttaag tcttgagaga gatttaaata aatttgttta tactgtggaa
      541 ggtgtagatg ataataatga atataagatg aaaattgatg ctaatacaaa agatgtatta
      601 gaagataaaa cagaaaagtt ggattcagaa gatttaaatg gagttgctag aaaagaaaaa
      661 ttagatttaa atgacataat gacacctcaa caagctatgg aaattgcatt aaaagaacaa
      721 aatggaatag ttaaagaatg gagtttagac aaagatttag atgttacttt ttataaaata
      781 agaatagata aagataaaaa tgaatatgac ataaaagtag attctaaaaa gggaactgta
      841 ttgaaggtag aaaaagaaga ttagaagatt taaactatct ttaaaataat ttcttttttg
      901 aataaatttt gtttaaaata taacaagcag ggtataaaga gactaaataa ctattttagg
      961 aggagtacgg tatgtcattg aaatcactaa aaataaaaga aaatttatat tgggtaggtt
     1021 cgcttgaccc tgatttaaga gtatttgaca taattatgta tacaccttat ggaactactt
     1081 ataattcata tgtattaaaa ggaacagaaa aaacagtttt atttgagaca gttaaagata
     1141 agcattttga caattatatt gaaagattaa atgatttaaa tatagatttt gaaaaaatag
     1201 actatattgt tgtaagtcat actgaaccag accatgcagg aagcgttgaa aagcttttgg
     1261 atttagctaa aaatgcaaaa gtagtagctt cagaaacagc aattaaatat cttaaggaaa
     1321 tcgtaaacaa agactttgaa tatgttgcag ttacagatgg agatacatta tcaattgggg
     1381 acaaaacttt agaatttttc tctgtaccta tgcttcattg gccagatacc atatacacat
     1441 atataaaaga ggataaaact cttgtaacat gtgattcatt tggtagtcac tatagtaatg
     1501 ataagatagt aaatacactt gatgaaaatg aagaaaagga ttacttggat gctttaagat
     1561 actattatga ttgtataatg ggtccattta aaccatctat ggtaactgct atagaaaaga
     1621 taaaagattt agatatagat actgtatgtc caggtcatgg tccagtatta actgaaaatc
     1681 ctagaaaaat tatagacctt tattacaact ggagtgtaaa tgaacaaata aagttagaaa
     1741 aagaagttac aatttgttat gtttctgcac atggatatac aaagattatg gcagaagcta
     1801 taaaagcata tattgaaaaa aatagcaact ataaagtaaa tttatttgat gtaatagagc
     1861 ataagcaaga agatattttg gcaaaaatag cagtatcaca aggtgtatta tttggaacac
     1921 caacaatatt aggagatgcg ttaaagccta tatgggatat attaatatcg ttaaacccag
     1981 ttcttcatgg tggaaaagtt gcttcagtat ttggttcata tggatggagt ggagaaggta
     2041 tagaaaatgc tatggagaga ataagtcagc ttagaatgac agcagtaaaa ccttttgctg
     2101 ttaactttaa accatcaaat gaagagattg ataaattaca ttcttataca ggtaaattcc
     2161 tagataagtt aaattctact tttggaagta aaaagaaaac taagaaattt aaatgtgtaa
     2221 tttgtaatga agtttttgaa ggtgatagtg ctcctagtgt atgccctgta tgtggagcta
     2281 aggaagacca atttatagaa gttgaagaag atgaagttac ttttagaaaa gatactgatg
     2341 aatatttcgt aatagtagga aatggagcag ctggttttta tgcagcagat gctataagaa
     2401 aaagaaataa aacttgtaag ataactatga tttctaatga agatgagttg acttactata
     2461 gacctgcact ttctgatggt ataaatgaag aacttggttc agatttctac atggaagata
     2521 aagattggta tgataaaaat aatatagtag taatattagg aacgaatgta gataaattag
     2581 atgaagtgaa taaaactatt atagtgaatg atggagctat taaatttgat aagcttgtaa
     2641 tagctacagg aagtagaaac tttataccac caattaaggg ccatgattta gaaaatgtgt
     2701 ttactcttag aaatataaaa gatttatata gtgtaaaaga agcactagaa aaatctaaga
     2761 aagttgtagt gattggtggc ggtttattgg gacttgaagc tgcatgggaa tttagactaa
     2821 aaggattaga agtagtagta gttgaagcca tggatagcat actatcaaaa caacttgata
     2881 aagaaggtag taaaatatta gaacaatgtg taagagatac aggaatagat gtaagattgg
     2941 gtgtagcagt tgatggtatt gaaggtgatg gaaaagctca aaaagttgta tttaaagatg
     3001 gagatagtgt tgactgtgat atggtagtat tttcaattgg tgtaagagca aacactcaaa
     3061 tggttcagga tacatctgta aaaattgata gaggtattgt tgtagataag acattacaga
     3121 caaatattaa agatatatat gcttgtggag atgttgcaca agtgggaaat attagtttag
     3181 caatatggcc atcttcagta gaaatgggaa aaatagcagg ggcaaatgca agtggagata
     3241 atttgacatt tgaaagtgaa gtatatccag tttcattaga tgcaatgaat gtaaaagtat
     3301 ttagtattgg taatatacaa aattttgata aagaaatttc atcaaaagat gaaggtcaaa
     3361 gaatatataa aaaattattt atgaaagatg gttcattagt tggagctata cttataaatg
     3421 atttaagctg tactgttaaa ttgataagat taatatctga aaaaggtgat tttgaggata
     3481 ttatgaaggc tgatatacta taatttaaat acattaaaat aaaaaggagt tgtctcaaaa
     3541 ttgatttttt tctaatcaaa ttttaaattc aactcctttt ttgaattttt atataaaata
     3601 acatggaaat tttagtaatg tctgtggtta catacatagg tttaattgtt ttttatatgg
     3661 attgtctctg gtataataaa ttgaattgtg tttgactgat agatattttt attgaaagtt
     3721 aatacctgtt atgcgataat aaggacgtgt taggggagtt tttataataa caattaatct
     3781 cagtttttgt gttccaatag tagcatcaac acattctgat gtagtagttc ttttcttata
     3841 aaaattagtt acaaatatgc ttgtaattat ttgatatgta aatttaccaa tattataaat
     3901 gatgacctcg ataataagga gagtgaaaaa taatctatga acgaaaatat tttgattgtg
     3961 gatgatgaaa aagaaatagc agatttaatt gaagtatatt taaaaaatga aggttttaca
     4021 gtatacaagt tttatacagg taaggaagct ctagaatgta ttgaatctaa aaatttggat
     4081 atggctattt tagatattat gcttcctgat attgatggat ttcatatttg ccagaaaatt
     4141 cgagaaaaat actattatcc tatcattatg ttaacagcta aaattgaaga tatagacaag
     4201 ataatgggtt taaccatagg tgctgatgat tatataacaa agccatttaa ccctttggaa
     4261 gttgttgcaa gagtaaagac acaattaaga agatatatgc gatataataa ttcttatgaa
     4321 caacagtcga taattgttaa tgagtatgat attaaaggat tgattatcaa taaagaaaca
     4381 cataaatgta gtttatttgg gaaagaagta gcattaacac cgattgaatt ttctattctt
     4441 tggtatttat gtgaacatca aggaaaagtg gttccttctg aagaattgtt tgaagctgta
     4501 tggggagaaa aatatcttga taataataac acagttatgg ctcatatagg gcgattacgt
     4561 gaaaaaattc atgaaccttc taaaaacccg aaatttataa aaactgtatg gggagtaggt
     4621 tatacaattg aaaagtaaaa atattaaagt caatcctgac tttactcaag tgagaaataa
     4681 aatttttatg agaacagctt taatggcatt tatagccatt attttcatat ggattttata
     4741 ttcttttata ttgtatggta agttttctat ctggatagta tcattctttg aaaatgcttt
     4801 tcgtatggaa tataaagctg cattgaattt atatcagcag attttccgta atagtatgga
     4861 gctcttcatg atactagcta tggtgattgt gttttttata atattccgtg tttatttaaa
     4921 ttggtttaca aaatatttta gtgaaataaa tcaaggtatt gactctctta tcaaagaaga
     4981 tgttggagaa gtggctttat ctccagagtt attggcaata gaaaagaaaa taaactcaat
     5041 taaacatata cttgaacaac gtaaatttga gacacaaatg gcagaacaac gtaagaatga
     5101 acttattgtt tatcttgcac atgatttaaa aacaccactt acatcagtta tagggtatct
     5161 gacactactt cgagatgaaa gtcagatttc tgaagaactg cgaaaaaaat atttatctat
     5221 ttcgttggat aaggcagagc gtcttgaaga tttaattaat gaattctttg aaattacaag
     5281 gtttaattta tcaaatatat cacttgaata cagtacagta agcttaactc gtatgcttga
     5341 acaactaaca tatgagttta aacctacttt gatgagtaag aatttaaaat atacactgaa
     5401 tgttacacca aatatgatga taaggtgtga tgttaataaa atgcaacgtg tatttgataa
     5461 cttattacga aatgctgttt attatagttt tgaagatact actattgaaa taacagctgt
     5521 acaggaggat gattatataa agcttaaatt tatgaatcat agcaatacga ttccagagga
     5581 aaaacttgag cgtatttttg aacaatttta caggttggat acatctcgta attcaaacag
     5641 tggtagagct gggttgggac ttgctatagc taaagaaata gtggagcttc ataacgggac
     5701 aataacagct catagcgaga acaatataat tacctttaag gttattattc cgattgtatg
     5761 aaatttgtaa gaatttaagt ataaaaaaat aggaaattct ttaggataaa taaataaaga
     5821 gcactcttgt tattgatata attactgtat caaaacaaga gtgcttttat tttgatacag
     5881 taattatatc aatagaaaaa tgtgaaaata tattatgtgg aacagatgca attgtaagtg
     5941 aaggttgatt ggatttgaaa tagaaaaagt attttaacat gtttctgtag attgtataaa
     6001 aataaataaa tcaacaaagg agaatcaaag atgaataata aaaaaattgc agttatattt
     6061 ggtggaaact caacagaata tgatgtatca ttacaatcag cttttgcagt acttgagaat
     6121 ttgaatacgg aaaaatatga tattatacca attggaatta caagggaggg taattggtat
     6181 cattatattg gagattataa taatatccag aataacactt ggtttgaaag ggatactgat
     6241 ataattccag ttattgtttc gcagaaccgt gtcaaaaatg gtattattga atttttaatt
     6301 cctgatgctg tttctcagaa tcatattcca aatagtgcta ttgaatcatg tgaaaatgat
     6361 attaaataca ctaaacttga ttttgtattt cctatattgc atggaaaaaa tggagaagat
     6421 ggaacagtgc aggggttatt tgaattggca ggtatacagg ttattggatg tggtactctt
     6481 tcttcagcat tatgtatgga caaagacaaa tcacataaac ttgttcattc agaaggtatt
     6541 aaagtaccaa aatcaatatt actaaaatac tcagataaat ttaatgtggc tgaactgtca
     6601 aaagacttaa cttatccatt atttataaaa cctgtgcgtg caggttcatc atttggtatt
     6661 agtaaaattt ataaaaaaga agagttacaa gtagcagtag acttggcttt tgaacatgat
     6721 aatgaagtaa taattgagga aaatattgat ggttttgagg tagggtgtgc agttttagga
     6781 aacgatgact tacttgttgg aagagtagat gaaatagaat tgtcaaaagg attttttgat
     6841 tatacagaaa aatatacatt gaaaagttca aaaattcata tgccagctag aattgatttg
     6901 gattgtgaga aaagaataca agagacagca aaaattattt atagaactct tggatgttct
     6961 ggatttgcta gagtagatat gtttttaact ccatctggtg aaattatttt taatgaagtc
     7021 aatacaattc ctggctttac ttctcatagt cgttatccaa atatgatgaa aggtattgga
     7081 ctgtcttttg aagaaatatt ggacaagata attgaggtgt acataaaatg atgaataata
     7141 ttttattaga taaaaataaa gaagataaaa tgacaaatac tatcttattg actaaagata
     7201 aagtttatga tgggaatcta attctagtaa atgctttttt accagttaaa acatctgaag
     7261 atatagattt aattcctgta gatacaaggt ttccaagtat tcttatgaaa cgtgaagcta
     7321 caaacatttt acaaaatatt ttaaaaagta tatgtggaat aaatgaaata gtacctgtaa
     7381 gtggatatcg tactgcagag gaacaacaag atatatattc aagttctctg cgtgacaatg
     7441 gaaaagactt tactaaaaag tttgtagcac ttccaaatca cagtgaacat cagacagggc
     7501 ttgctattga tttagggtta aagaaagaag ttatagattt tatctgccct gaatttcctt
     7561 ataatggtat ttgtaatgag tttcgtaagg cagcactaca ttatggtttt atagagcgtt
     7621 atcagtgtaa aaaagaagaa ataacaggaa tatctcaaga accatggcat tttcgttatg
     7681 tgggatatcc gcattctgag attatcaata aaatgaatct cgctcttgaa gaatatatag
     7741 aatatattaa gagattttcg tatacaaatt gtttaaaaat agaagataaa gaaaaaatta
     7801 tagaaatctt ttatgtacct attcatacta aagaagaagt gagaatctct atacctgaac
     7861 aatgtgtata tcaaatatcg ggtaacaata aggatggttt tattgtgaca ttttggagaa
     7921 atagaaagga ctaagaaatg gaggaacaag aatgattagg aataaatctt atgcagggct
     7981 tgattatttt aggattatag ctgcattact tataattgca attcatacat ctccattatt
     8041 atcatatagt aaaatggctg actttatgtt aactagtata attgctcgta ttgctgtgcc
     8101 attctttttt atgctatcag gcttttttct aatttcaaca tataattata attgtaataa
     8161 actgaaatct tttctaaaaa atgtattatt tatttacggg atagctattg taatttatat
     8221 tcccttaaat atttacactg gatatttttc catgaataat ttagtgccca atattattaa
     8281 ggacattgta tttgatggga ctttatatca tttatggtat ctacctgcat caattattgg
     8341 tgcaagtatt gcatactttc ttgtaaaaaa actaggttta aagtactcac tagtaatcac
     8401 tattgttatt tatgtaattg gtatgtttgg tgatagttat tatggttttt tagaaaaaat
     8461 accactatta aagaatttat atgggtatat ttttgaagta tcagattata cacgaaatgg
     8521 tatatttttt gcacctgtat ttttcatact tggtggaata atatctaata aatctaatta
     8581 tatgtcaact aaaaatagct tgattggatt tcttatatca ttcttactta tgttatgtga
     8641 gggaatgttt ttacataaac taggggtaca gcgtcatgat agcatgtata ttatgttatt
     8701 gccatgtatg tatttcttat ttacagcctt aacatttttg aaaggttctc gagctaggtt
     8761 attgcgaaca tcatcattaa ttatttatat tatacatcct atgatgattg ttgttattcg
     8821 tatgttttct aaaatattcg gaatacaaac tgtcttggtt gacaatagcc ttattcatta
     8881 tatagtggta agtatagcat cttttatagc ttttataatt attatattga ttcttaaacc
     8941 tctaaaaaaa gacttgaaag gagaacataa ggtaaatacc aatagagctt ggattgaaat
     9001 tgatttaaat aatttggaac ataatgtaaa gatgatacaa aaagctatgc cagaagattg
     9061 tgaattgatg gcagttgtaa aagctaatgc ctatggtcat agtgcttttg aagtagcgac
     9121 ttgtgcaaac caaataggtg taaaagcatt tgcagtagca acaatagatg aggggattga
     9181 tttacgtcga tatggaatac taggagaaat attgattctt ggatatacta acccaataag
     9241 ggcaaaggaa cttcataaat acaatcttac acagagtgtt attgacctta atcatgctat
     9301 ctctttaaac aaacagaaat acaacataaa atcacacatt aaaattgata caggtatgca
     9361 cagactgggt tttgatgtta atgatgtgag gtcaatttta aaggtattta aattaaaata
     9421 cttagatata tgtggcatat ttacacactt gtgtgtttca gatagtctga aagatgaaga
     9481 tgtagacttt acaaataaac aaattgaatg tttttataag ttaattgatt ttctgttaaa
     9541 aaaaggtata aaaattccta aagtacatat tcaaagtagt tatggttttt ttaattatcc
     9601 caatcttaag tgtaattatg taagaattgg aattgcatta tacgggatat taagttctcc
     9661 aaatgatacg actaaattgc aacttgattt acgacctgtt ttatccttaa aatcacaagt
     9721 aattcttatt agaaaaatac aaaaagatga tagttttgga tatggaagag tctttattgc
     9781 aagcagagat agcgtaattg ctatattatc tattggctat gccgatggta tacctagaaa
     9841 tttatcctgt ggaaaaagtt acgtaataat aaatggttgt agagcagcaa tagtgggtcg
     9901 aatttgcatg gaccaacttg ctgttgatat tacagatata cctaatgtag aagttggtaa
     9961 tacggcaata ataataggaa gagataattt atctgaatta tctgcttctg aagttgcaaa
    10021 taactcatgt agtatatcga atgaattatt gagcagagta ggaagaaggt taaatgttat
    10081 aaagaagtaa ctcaattaaa tagtaatatt tgttgtactg tgtaatttat tttactctga
    10141 ctagacattt ttagtaatat tatgtctaat atatattttt tataacttac atgacaattt
    10201 aagttataaa aaggtgatgt ttcagatttt tattttgaaa catcaccttt tttgttataa
    10261 tatataataa aataattata ccttaactgt aaacttatat agattattta ctttttaata
    10321 ttagattcat tttttgagat tggtatataa taaacatata gagtatataa taatagttaa
    10381 agttaaaaaa ggggaaaagc aatatgcagt atatacaaga actacttgat ttgactcaaa
    10441 attattgggt gttagccaca ataatcggct tattaagtgc atttatagaa agctttatac
    10501 cagccttacc acttgttgct atagttacag caaatgctgc aatacaagga ttatttattg
    10561 gatgtttgtt atcatggatt ggctcaggac ttgggacaac ttcattattc ttattaataa
    10621 gcagatttaa tgatagtaag ctttttaata agttgagaaa tagtaaaact gaaaaagcaa
    10681 taagttggat ggataaacag ggatttaagt tattatttat agcgtatgcc tgtccattta
    10741 tgcccggttg tttagttact atcgcatcag cttttggtaa aaaagattta aaagattttg
    10801 tgccagcaat gttggcagga aaatttgtaa tgtttatagt tataagttac gtggcaagtg
    10861 atatagaagg ttttataaca agtcctttaa agatagcatc atttatatta ttggtgtttt
    10921 tgtcatggaa gattggaaat agagtaaata aaaatcttga aaatcataat tatgatttcc
    10981 atcataaaaa acatcacaat gataaagatg ataaaatgat ttagcttgta cgaaataaaa
    11041 cgtatcttaa aatgatttag tactaaatta ttttaagata cgttttattt tttgtattaa
    11101 agtacaaaat ttttagttct tttgtaaact aaaatatata aaacttattt atacttagtt
    11161 caaaatattg ttatttattt tttctacaac tataataaaa tataaaattg atatccaatc
    11221 aaaaaaataa ctatgaaatt taatagctta gatatgaatt tttctgtttt tgagttagtt
    11281 tttataggta gtaaagaaat gtttatagta atgggataaa acaattcaat accttcttta
    11341 gtaataaggt caagacacaa gtgagataga tatcctatta taaacccact ggacaaacat
    11401 gagaaaacta tattattgtt agtgaagatt gtcagagatt taaaaaaact ataaataagt
    11461 aataaggcaa ttagactgtg agtaaaccct ctatgtctaa acctacttcc aaataatttg
    11521 tatattaaca taaatttttt acttatgtaa gaacctctca tatctatatc tggaaataaa
    11581 gaacctaaat atgcaaaata aatataaatt ataattaata ctattttata tgcaatatcg
    11641 tatttaacta ggtacagatt gtttataaag gggagtatca aaagtgcgaa tatataacct
    11701 cccctttcat gtgtttcttt tatcatataa aaatcctcct gaatcgtcac tataaacatt
    11761 atattggtaa atttagacta tcttttatta tattatatag caaacataag tttttttcaa
    11821 aaggatttta atatttaatt aatcttgaga ttttaaattt ttgtaatttt ctaaagcacc
    11881 attccaattt actacattaa accagttgtc aatgtattca tttcttctat tttgatattt
    11941 taaatagtaa gcatgctccc aaacatcaag tcctattata ggagttaggt ttttacttac
    12001 agggctatcc tgatttggag tagtcataat agataatttg ccatctttag tagctacaag
    12061 ccaagcccaa ccagaaccaa agacatctaa agcagatttt tggaactctt gcttaaattt
    12121 ttcaaaagaa ccaaagtctc tatcaatagc ttcttttaaa gattcagaag gtatggtttt
    12181 ttctggcgtc attatatcaa aaaagaattt atgattataa gctccacctg cattatttct
    12241 tacagttgta gcaatatctt taggtaaaga atctaaattt tgcaataatt cacataaaga
    12301 ataattataa agctcaggat atttttcaag agcagcattt aatttatcaa cataagcttg
    12361 ataatgctta tcatgatgca gtttcattgt ttctttatct atataaggtt caagtgcatc
    12421 atatgcataa ggtaatggtt taaccttaaa tttgttattt tcaggtgtaa aagcaaatga
    12481 agttatgcac tgtgagatta taaataaaga cataataact ggtattaata tttttttctt
    12541 cataaaaatc acctcctaat atagtatttc tagaaataaa aaaaatatga aatattaaca
    12601 gataatttat aagaatttaa tagcaatttc attttaaatt gaataagttt taaagccaaa
    12661 gacaaaacta tgaaatatag aataagacta aaggacagaa aggaattttg attatatgga
    12721 cggcaatatt tcaatttatt ataaaggtga tatatctaaa aaagaagata ttaaatttaa
    12781 aataaaagaa tctgtaaata atacaagact ttctagtaga atagagtata aggatgagga
    12841 aaaaactttt gattttgaaa gatttaatgt aattgatgct atttatggaa ataaaccatt
    12901 tgaaaaagat ggaaaagtta ttgtttttaa tggaaatata tataactatc atgaaataaa
    12961 agaagaatta attaaaaaag gacacaattt tactacaaat gatgatattg aagtcttatt
    13021 ggcatcttat atagaatttg gtaagaattg tgtacataag attaaaggaa tgttcaattt
    13081 tataatctat gatagagaaa atgaaagtat atttggagca agagatttat ttgggataaa
    13141 accactttat tatataaata aggaaaatgc aataattttt tcctcagagt ataagttttt
    13201 acttgaatat atgaaaaatt taaatataaa tgaaagaagc ttacaaagtt atttttcatt
    13261 tcaatatgta cttcctgaag atactatgat acaaggaata aggctgatac cagcaggtca
    13321 ctattttagg gtagaaaatg gtatactatc tttaaagaga tataataaac ttgagtttag
    13381 aagtagtaca aaattttttt atactaaaaa taacttaggc aatagagatg tgaatgagga
    13441 tgatataaga aatatagtag tagattcaat agtaactcat atggaagagg agaaagaaat
    13501 tggaacattt ctgtctggtg gaatagattc atctattata actactgtgg cttcacaaat
    13561 taatccaaat ataaaatctt tttctgcagg ctttagtgtc aaaggatata gtgaattaga
    13621 agtagcaaag aaaacagctg ataagttagg tatagaaaat atccagatta atataacaca
    13681 agatgaatat ataaaatcat taccgaatgt aatttattct ttggatgacc ctatagcaga
    13741 cccttcagaa gtaggtcttt atttcttaat taaagaggca ggtaaacatg ttaaagtagc
    13801 attgtctgga gaaggagcag atgaattatt tggaggatat aatatatata aagagtatag
    13861 tactatgaaa tcagttgtca attcacctac ttatattaaa agtatattag gaagagtttc
    13921 agaacttatg ccaaacataa aaggaagaaa ttatctttat agagctacaa caccattaga
    13981 aaaaagatat ataggaaatg caaaagtttt tgaaaacagc gaagtaaaaa gattcttttt
    14041 taagtataag gaaaagaata tatatgaata cctgttgtct aatttgtata gagatgcaca
    14101 aaaaaataat tacgattata taagtaaaat gcaacatata gatgtgaata catggcttca
    14161 aggcgatata cttcaaaaaa ttagcaaact ttctacagct gagcaggttg aacttagagt
    14221 accattttta tataaagatg tatttgatgt agcaaaaaat ttaagaatgg agcaaaaaat
    14281 aaataagaat aatacaaaag ttttacttag agaggctttt agagaaatag tcccagaaca
    14341 tgttgttcaa aggaaaaaat taggatttcc aactccaata agagtttggt taaaagattc
    14401 tctaggggat attgtaaagg aaactattta taattcaaat gtagatgaat ttatagataa
    14461 aaaatatgca ataaaacttt tagatacgca tcttaaaggt catagagata attcgagaaa
    14521 aatatggact atatttacat tttgtctatg gtatcaatta tttattgagc ataaaaatgt
    14581 cgagtattaa tactgttttc aatattaatc agagggcaaa agcatgcaat gttttcaccc
    14641 tcttgattat tatggaatag gataagtaga attttgattg attagtttac tatctcaata
    14701 aaattattgg caaatatttt gacaagatta ctttcaacag ctaaatttaa gttttgtcca
    14761 tcatcatatc cagcggaaat caatcctagt aagtttccaa acatatctaa aagagctcct
    14821 cctgaactac cactagagat tggagctgta aattgtatca tttgaaccgt ttcaaaatca
    14881 cgaaaagctg agataattcc atctgaaact gtattaaaaa gacctaaagg gcttccaatt
    14941 gcaactattt tttgacctct cacaggtttt ttactgactt taacaggtat tggcttgcat
    15001 tttctatcaa cctttatcac agctaaatca taatctgaat ggtattttat aatttggtaa
    15061 gatgtataaa ctttatcatc attttcaaat ctaactaaaa atgaataccc atcattgact
    15121 acatgaagat tcgtaagtat ataaccttca ttatttatta ctactccaga accgctctta
    15181 aacggtttat tttcgttatt gcacacaaca atcataacaa cagaagctga taactttgca
    15241 aggtcttcat aagaaagttc tacttcctca tcttgtacaa tttttttaga tgttagattt
    15301 gtgttattaa gtgtattttt agagttaggt ttattcgtag taggagaagt cttattggta
    15361 ttttcactgt aatttatatt tgtaatatgc ctttcaaaag gtatttctaa tatatttgga
    15421 gtcttcctag aaagttcaaa tagagtagaa aattttgaac attcaggata taaatcaaga
    15481 atatctttat ttggatttat atataaaata tcacacccaa gttgtgataa aaaatataag
    15541 aaaaaaagtt cttgcctttt aatatttcca aagtatacta tctttggtga aatagtagtc
    15601 ttcaccttgt tataaaataa tttaggtaga aaatagtcca tccaacacaa aagtttaact
    15661 gcaaagtttt tgatgataga ggatgtacaa tttggcatac ttgtggaaaa taaatctaaa
    15721 gtatttttaa atgcaatctt tttagtccaa tttaaggtgt cattttctat tttacatgga
    15781 aagtcgatat tatataaatc ccaactgtta aacttagaac tattataaat attaaaaatt
    15841 ttaagcatct tatctgtttg ttctttgtca aaatttattt ttagattgtt taatctaata
    15901 tagggaattg taggattatt aaaaaaataa gtatctatat ttttaatttt ttctatgtat
    15961 ttatcaattg aatcatcaac acctatatat cttgtaaagt agacttcttt aatatatgaa
    16021 gaacgcttat ttttataggt agtatcagat ataaattcaa ttagaggttc agttgacttt
    16081 tttattgaaa tctttaatgg tttaatagta caaatcatat tttttctcct ataataagat
    16141 gatataatct attataaaac aacttaaaac aatatagtac aataattttg tagtttcaaa
    16201 ataaaatatg tacttgttta tataaatgat atataattac atattaaaca tagcttttat
    16261 acatttaata aagtatgtaa aatctatgta aaaagtaaga aatataaaca tttttttaat
    16321 tatattttaa aaatatcaag caagttttct tcacaaatga ataaaaaatg ttataatatg
    16381 attaaagaaa aagataaata attagcaaga tttgtttagc taaaattaac aagggagcga
    16441 taaattatgg gtataacatt atcaaaaggc caaaaggttg atttaactaa aggaaatcca
    16501 ggtcttaaaa atattttagt aggtttagga tgggatacta acaagtatga tggtggattt
    16561 gactttgatt tagatacagc agcattttta acaggagcaa gtggaagtgt tactaatgat
    16621 ggagattttg tattttacaa caatttaaaa catacatctg gagcagttga gcatctagga
    16681 gataacagaa ctggcgaagg tgatggagat gatgaacaaa tagttgttga tttatctaag
    16741 attcctggag aaataagcaa gatttctttt actgttacaa ttcatgatgc aacagaaaga
    16801 agacaaaatt ttggacaagt aagtaattct tatataagaa tagtagataa agacacaaat
    16861 gaagagttaa taaagtatga attaggagaa gattttagta tagaaacagc tatagtagta
    16921 gctgaaatat ataagcacaa tggagaatgg aagtttaatg cactaggttc tggctttgaa
    16981 ggtggtcttg ctgcattatg tggaaacttt ggaataaact tataatttca actataacaa
    17041 taaactaaag ggggatattt tccatggcta tagtattaaa aaaaggacaa aaaatcgatt
    17101 taactaaggg aaatccaggt cttaaaaata taaaacttgg actaggatgg gatacaaatt
    17161 catttgatag tggctatgat tatgatttag atgtaagtgt tttcatggtt ggagaatctc
    17221 aaagagttga aaaagatgaa gattttatat tctacaataa cttaaaacat ccatctggag
    17281 cagttgaaca cttaggtgat aatagaactg gtgaaggtga tggagatgat gaggaaatat
    17341 tagtgaattt agagacaatg ccaaagcata tacaaaagat agctgtaaca gttacaatat
    17401 atgaggctgc tgaaagaaga caaaattttg gacaagtaag caactcatat ataagagtat
    17461 taaattctga aaatgatgaa gaaatattaa gatatgactt aggtgaagaa tttagtatag
    17521 aaactgcaat tacagtatgt gagatatata agtataatgg agaatggaag tttagtgcag
    17581 ttggagcagg atttgaaggt ggcttagaag cactttgtag aaactatggc ttaaatgttt
    17641 aatttaagca atataatata ttaaatataa ataacctata caaataatgt ataggttata
    17701 ttatataaaa ttttgtggag gtttagtatg tcgattaatt tatcaaaagg tgataaaata
    17761 gatttaaaaa aatctaaccc aggactgagt aacatacttg taggtctagg atgggaccct
    17821 gtgcaacaat ctggcggagg tttttttaaa tcgttatttg gtggaggaca agctgatata
    17881 gattgtgatg catctgtatt tatgcttaat caagaaggta aattaagtgg aataaaagat
    17941 ttaatttatt ttggaaatct aaaaagtgcc tgtaaatcag ttttgcatac aggagacaat
    18001 ctaactggtg agggtacagg tgatgatgaa caaatcctag ttaatttgga taaagttcca
    18061 tcaaatattc ataaattatt gtttgtagta aatatataca attgtgtaga tagaaaacaa
    18121 cactttggaa tgatagaaaa tgcctatata agagttgaag accaaggtaa taagaaagag
    18181 atagcaaaat acaatctatc tgataattat tctgaaaaaa ctactcttat agtaggagct
    18241 atatatagaa aagatggaag ttggcaattt aaagcaattg gtgaaggaac aaaagatgcg
    18301 ggtcttaaag aagtaatgca aaatttagac aggattgagt gtgcatatgg aatttaataa
    18361 tgatatcaaa tattataatg tagataaaga agaagttaca aaagacttat ctgttaatcc
    18421 tgaaaaaggt ttatcagaat cagaagtcaa gactagaaga gaaaaatatg gtttgaatga
    18481 atttactcca aaagaagagg gtagtttttg ggatgattta aaggaaagtt taagtgaacc
    18541 aatgatagtt atcttgatta ttgcagcagt agtaagtgca gtaattgggg aaactcatga
    18601 tgcaataggg attgtaggtg ctatagcaat aggtatagca ataggtatga ttacagaagg
    18661 tcgttctaag aaagcagcag aggctctttc taagttgact gaaaacatag aagtaaaagt
    18721 attgagagat ggggaagtac atcaaatttc taagagtgaa ttggtaccag gtgatatagt
    18781 atatattgaa actggtgaca tggtacctgc tgatggtaga cttatagaaa gtataaacct
    18841 taaaattaga gaagatatgt taacaggaga atctgatgac gtatctaaaa agtgtgatgt
    18901 agtagtttct atggaagaga tagaatctaa aggagcagta gtagtacagg aaccaatacc
    18961 tgcaaaacag ataaatatgg tgtttggtgg tacacttgta gcttatggta gaggagctct
    19021 agttgtaact tcaattggag ataatagtga aatgggtaaa attgctcaaa acttatcaga
    19081 aacagatgag caaactccac ttcagataaa acttggaaat ttaggtggtt tgatagccaa
    19141 agtttctagt gcagtagcag gattactatt tatatttatg gttttccaaa tgataagtaa
    19201 gaatgtatta aatgtagata tgtctggaat attaccgttt ttagaatcaa tagacccagt
    19261 taaaacagca tttacagtat gtgttgcgtt gatagttgca gcagtgccag aaggtcttcc
    19321 aactatgata aatatgacac ttgcaataac aatgcaaaaa atggctaaaa taaatgcatt
    19381 ggttactaaa aaagaagctt gtgaaacgat aggttctgtt tctgtaatat gttcagataa
    19441 aactggtaca ttaactgaaa atagaatgac tgtagaagtt gcatatgttg atggcagata
    19501 tattgaaagt tcagaagagg aaataaatag ttattttgaa gaaaactgta tgataaactc
    19561 tacagctgat gtagagcaca atgatggtga tattaagtat ttaggaagtg ctactgaatg
    19621 tgcattgctt ttatattaca aaaacgtaga ttatagacaa gttagaaaaa attctaatat
    19681 agtagctcaa aatcctttta cttcagattc aaagagaatg acttctgtta taggtcaaga
    19741 taatcatcat gtactattat caaaaggagc accagaagtc ttacttgaat tatgttcaca
    19801 tattcaaaga ggaaaagaca tagttccatt aactgaaaat ataaaacatg agattttaga
    19861 agaaataaag aaattgcaaa taaaatcaat gagaacttta gggtttgcat ataaagaaat
    19921 ctcacaagct gaagaagaag cagcagtaac tgctgaaagt gatgctatga atgtaagtgc
    19981 aatggaaaac aatttagtat ttagtggttt tgttggtata agagacccac ttagaaaaga
    20041 tgttatagag tctgtaaata cagcaaataa agctggtgtt tctgtaaaaa tgcttacagg
    20101 agataatata aatacggcaa gagctatagg tgaagagtta ggcctattaa aaaataatat
    20161 gagagtggtt gaagcttcat atatagatac tttagatgat gaagaattaa aacaagagat
    20221 acaaagtatt tcaatcgtgg caagaagtaa accagatagt aaaatgagaa tagtttcagc
    20281 tctgcaaaag agcggagatg ttgttgcagt aacaggtgat ggtataaatg atgctccagc
    20341 actttcaaaa gcagatgttg gtatagcaat gggtatatct ggtacagagg tatctaaaaa
    20401 cgcagcagac ataattttaa ctgatgatag ttttagtacc attgtaaaag gtattaaatg
    20461 gggtagagga atttatgata acttccaaag attcgttcaa ttccaattaa ctgtaaatgt
    20521 aattgcattt ttagtggcta taatatctca agttatggga caagagatgc catttactac
    20581 aatacaatta ttatgggtaa acatcattat ggatggacca ccagcactag cattaggttt
    20641 agagccagtt agggaccatg tgttaaatag aaaacctgtt gatagaaaag ccaatataat
    20701 ttctaagtca atggtgtata caatagtatt aaatgcattt tatataacag caatactaat
    20761 gttacaatct acatttaatt tcttaggagt tgatgaagca cataagggaa cagtaatgtt
    20821 tgcgttattt gcttttagtg cactgtttaa tgcatttaac tgtagagagt ttaatgcaga
    20881 tagtatcttc cctaatttta cacataacaa attagcacta caaataatag tgttgacagg
    20941 aattgcacaa gtaatattta ctcagctatt ccaagatttc tttaactctg tagcaatgga
    21001 ttttatgaca tgggtaaaag ttttatgtgt agcagcaagt gtaattgtgg ttaatgaagt
    21061 tgtaaaatgt ataataagac tggtaaaacc aaaaaagact gcttaaaaca aattttttag
    21121 aagaaaacag actgactcaa aatatgaatt ttgggtcagt tctgaataaa catttaaatt
    21181 gggaggatag ttatgggtga ctcaaaggta tttgaaaaaa tattctccag ccaatcagat
    21241 agaggaaatt acactccttc aaagggatat ctaagttatt ttatttcgta tattggttta
    21301 gaagatgaag ttttgtacaa tctcgagata tttaaaacaa aacaaaatat tgatagcaaa
    21361 aaagatattg ctttatttac tgatgttata gcaaatccta gtgattttga tattataaat
    21421 tattttaaaa gtggacttca aaaatataga actagcatgg aagatgtaga tataaatatt
    21481 ttgggatttg aagagattga ttataaaata aagcaagcaa tggatagagt gttaaaagaa
    21541 gaggaaaaag aatttactaa tgatagagtt aaacaaaatt ttatagtgaa aataatggca
    21601 tggataaaaa tttatatcgg tgctttagat ataaataaaa atgaagctcc aaaagtaata
    21661 ttttatggag atataaaaaa acatgaagtt tatttactct taatattata cttggcaggt
    21721 tttgatgttt tatatcttaa tccaaattca aagagtaata tagatatttt aaaatcagaa
    21781 agatacaata tagagtttga agaagccaac ataatagaag aaaaaatttc ttttgaagaa
    21841 agggttattt taggggaaaa aatagataaa agttctgtaa aaaaagcttt tactgttggg
    21901 gcagaagcat caaagcgtat aagtgaggaa ttgttaaatg atgcaggatt tataaaacct
    21961 tggcaactcc aagatagaaa aataaaaaat ctacttctaa gttcaactgt tgatgaaata
    22021 tcaatatact ggaatcaacc acttaaatta agaccaggat ttaagtttaa tgatgctatt
    22081 gtagaagctc caaattttct ttctaagatt aatggaatat ataacgataa gaatgaatat
    22141 attaagtttt tagatttatt aagagattcg gaaagttcaa catttattga atttaatgga
    22201 gatgtagata gattttcaaa agcttttaca agagaagctt ttagtttatc ctttttattg
    22261 gattcaaaag gtgcaataga taaaaactct gttttaaata ataaagatta ttccatatca
    22321 acactagcat tgaatcaaca aattatgatt ttagagaaag tggaagagtt gttagaagga
    22381 agtatgtttt tgaatggttt aagtggagaa gacaagataa aaggtctatt tacagtactt
    22441 cacatggata agaaatttgt tcatatgatg aacaatttcg attactcact tataaaccca
    22501 aaattgatta tatacatgta caagagtatt gtatttgata aagaaatagt ttttcttatg
    22561 cttttactta gtaagattgg atttgatatt atcatattat gtccaggagg agaaaacaat
    22621 atagagaatg ttataaataa ccaattgatt gatgtacaca gattggataa aatggtatat
    22681 gaccttaaat taaattcgct tgaaaatgat atacctttac ttaaaaaaat ttttggaaag
    22741 aggagacgat tttagatggg gataaatata aatagttttt caaaagataa gaactctgta
    22801 gaggttactg agaatttgcc tacagcagtt caagaagaaa acttcgatat aatggaatat
    22861 acaaataata aaaaaaatga actgagaaag tctaaggaag ttgaggcatt gacatctctt
    22921 atagaagtag aaaatccaga tacgatttta cagtttggta ggaaagcatc tgaaggagta
    22981 gcaagagttt ctgatagcct tttaaataca ataaaattaa atagaaatga agaaaattct
    23041 aaaatgctgg ttcatttaac taaaataatg gataagtttg atttagacga ttttcaagaa
    23101 actaaggaac caaatttcgt tcaaaaactt ttcaaaaaag ctaataatgc cattgaaatg
    23161 atgtttcaaa agtatgaaac attgggagga gaagttgaga aaattcaaat tgagcttgag
    23221 caatacgaaa gagatatagc actttctaat aagcaaatag gtgctatgtt aaatgaaaac
    23281 tttgagtttt ataatgaact tcaaaaatat attgttgctg gagaaatggc aatagaagaa
    23341 atggataatg aaatactacc tttctttaaa caaaaatcag agactagtgg agaccaaatg
    23401 gatgttgtca attatcaaga actattaaaa gtttatgata tgttaaatca aagagtctat
    23461 gatttaagga tagcagaaaa tatagctatc caaacaatac ctatgcttag aggtatgcaa
    23521 cataataatt atggtttaat tagaaaaata aatagtgcat ttgtcgtaac tttaccagta
    23581 tttaaacaat gtttatctca agctatatta cttaaaaagc aagaattaca agcaaaatct
    23641 ctaaaagcac ttgatgacaa aactaatgaa ttattgctta gaaatgcaca aaatgtaagt
    23701 actcaaagtg cacaaatagc tagaatggct ggaacaagtt ctgttcaaat agaaacattg
    23761 gaaaaaatgt acaatactat caagtctggt atagatgaaa ctatgagaat agaagaaaac
    23821 aatagagctt taattaagga taatacaaag agattggaag aattaaatac gactataatt
    23881 tataataagt agtattatat taagggctaa tttgtataaa gttggccctt tctatgtata
    23941 tgaggaggct agacattgaa atatttcgat tatatctgca aagatgattt ggagagaatt
    24001 tttttgaaag agccagaaga ctttagtgct aagactgaaa aagatgtgtt gaaatatgca
    24061 ctgggcgctt ttttatacgt tccagctact caatataata tgatttataa gagtattata
    24121 ggggatgtta agggagttag accattagct atttgtttag aagatgctgt tggagtaaat
    24181 ggagagttag aggctataga aaatcttaga ttaattttaa aaaatattag caatgaaagt
    24241 ataactaata aagatggaat accactaatt tttgtaagaa taaaagatgt ggagcaactg
    24301 ttgagaatta aagagattat aattaaaaat agtcattcta taacaggaat attaattcct
    24361 aaagtaaatt cggagttaat tgaaaattgt atagaagctt tagattctat gaatcttcaa
    24421 gatatgtatg ttattccaat aatagagaca aaagaattta tatataatga aaaaaaagaa
    24481 cttagtttta ctaatttgta caatgctatt ttaagacata agtcaagaat attaagcatt
    24541 agagtaggca taactgatat attagggatg tatggtataa ggagagataa aaacttctct
    24601 atatataata atttgatttg ttcttcattt atattagata taatcacata tcttcaaaga
    24661 ccagagttag atatacctat aagtggtgga gtatcagaat tttttgatat gacaaataag
    24721 gatataagaa ataagtatat agaagaaata ttattggata aatatcatgg attaattgga
    24781 aagaccgtaa ttcatccaat gcaaattcaa attgtacaag cgctatctac agtatcatat
    24841 gaagatttta ctgatgcttt ggatatactg gatagtacag acagtaagta tggtgtgagc
    24901 aagggtgtat taggagagag aatgaatgaa acaaatccac attttttatg ggctaaaaaa
    24961 acattgattc tatctaaaat atatggtgta ttaaataaag gagtagacta tgaagaattg
    25021 cttaaatttt aattgtgaga ttgacattat tgataatcca ttgaatttag aactaaatga
    25081 ttttttagac gtaggaataa gaaataatag caaaagacgt tttttgttta tctcaaagaa
    25141 actcggtaaa catttagcat gtaagccaag tgagatggat aatttgggaa aattaatggc
    25201 tacaatttat aatgaaaaaa ataaggaaga atcaaatggt actgttatag cttttgctga
    25261 aactggtaca gctgttgggc atagtttttt tgattactta tgtggagatt atgaatttat
    25321 tcatactact agagagcagt ttgacgagtt agaaaatctg gaatttttag aggaacattc
    25381 ccatgcaaca gaccagaatc tatactttgg gatgcttaac aactttaaat ttggagatga
    25441 gataatattg gttgatgatg agattaccac agccaataca tgcatgaata taattaggaa
    25501 gattcaaagc atttatccta aaaagaaata cactatatgc tcaatactaa attggataag
    25561 tgatgaaaat ttaagtaaag ttactcgttt agaaagagag ctagattgta agatagattt
    25621 tgtatactta tttaaaggaa actttaaatt ttatatagat gaagatatta tttcaaatta
    25681 caacgacaat tatagtatta ctaaattaga gactatttca agtgataaag taaatttagt
    25741 agtaaatcat atttatgttg atttagaaga ttatattgga aataagaaat atgtaaaata
    25801 tacaggaaga tttggaatta atagaagaga acaatttaga ttaaaagaaa tcgttaagag
    25861 agaaagtaaa aaaataacta tggacagtaa agaatcttta aaaaaagaaa aagaaaagat
    25921 tctattttta ggtactgaag aatttatgta tatacctatg ctgtttgcaa aagaaaaaga
    25981 aaatcaatat gatatatact atcattcaac aacaagaagt ccaattatta atattgataa
    26041 gaataattat cctattaaaa gtaaatttat gctaaagagt ttttataata tagg
//
LOCUS       DAEQAF010000235        19405 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.guided.072, whole genome shotgun sequence.
ACCESSION   DAEQAF010000235 DAEQAF010000000
VERSION     DAEQAF010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 19405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19405
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.guided.072"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            140..1513
                     /locus_tag="KRN00_003747"
     CDS             140..1513
                     /locus_tag="KRN00_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBH1829519.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILANSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIEKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            1769..2836
                     /locus_tag="KRN00_003748"
     CDS             1769..2836
                     /locus_tag="KRN00_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBH1829520.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            2980..3288
                     /locus_tag="KRN00_003749"
     CDS             2980..3288
                     /locus_tag="KRN00_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBH1829521.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            3281..4711
                     /locus_tag="KRN00_003750"
     CDS             3281..4711
                     /locus_tag="KRN00_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBH1829522.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            4789..5163
                     /locus_tag="KRN00_003751"
     CDS             4789..5163
                     /locus_tag="KRN00_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBH1829523.1"
                     /translation="MKKREDDFEVRRKHLQELSDDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            5157..7361
                     /locus_tag="KRN00_003752"
     CDS             5157..7361
                     /locus_tag="KRN00_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBH1829524.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKNNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            7361..8770
                     /locus_tag="KRN00_003753"
     CDS             7361..8770
                     /locus_tag="KRN00_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBH1829525.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIKYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     FKLLLKSLNFEEERLCILG"
     gene            8755..9819
                     /locus_tag="KRN00_003754"
     CDS             8755..9819
                     /locus_tag="KRN00_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBH1829526.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVSKKIIV"
     gene            9849..11270
                     /gene="nhaC"
                     /locus_tag="KRN00_003755"
     CDS             9849..11270
                     /gene="nhaC"
                     /locus_tag="KRN00_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBH1829527.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VVFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            11534..11998
                     /locus_tag="KRN00_003756"
     CDS             11534..11998
                     /locus_tag="KRN00_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBH1829528.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLAKLDVEVGFPVATYIDGKNEILQRIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            12296..12658
                     /locus_tag="KRN00_003757"
     CDS             12296..12658
                     /locus_tag="KRN00_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBH1829529.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHLDGTIIEYVQHTKQD"
     gene            12726..13340
                     /locus_tag="KRN00_003758"
     CDS             12726..13340
                     /locus_tag="KRN00_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBH1829530.1"
                     /translation="MNEKWLEWAIELQSIAQAGITYGKDIYDIERYERIREISAEMIA
                     YKTDISTEKVRNLFCNESGYQTPKLDTRAVIFENGKILLVKENTGKWSLPGGWVEVNL
                     SVKENTIKEVKEEAGLDITADRIIAIQDRAKHNLPIYAYGVCKIFVLCTVIGGTFKEN
                     IETTEFSYFSENELPELATEKNTEEQIKMCFEACRTDTWTVIFD"
     gene            13360..13989
                     /locus_tag="KRN00_003759"
     CDS             13360..13989
                     /locus_tag="KRN00_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBH1829531.1"
                     /translation="MDYKEIVFDVDGTWIDTEYAILHSLQDTIKQINRKIIPIKELSF
                     ALGITGEDALRYLKIEDITIALSMWDRNMEKYKNTVLVFKEIKEMLTELIKLNIGIGI
                     VTSKTHEEFRNDFLSFDIAPYFNTVVCSNDTLEHKPKAVPLLKYMELTKCQNNELLYI
                     GDSIYDMQCAYRANVDFGLVKWGSGDRVSAVISFTTPLDLIRQLSVSSN"
     gene            14600..15460
                     /locus_tag="KRN00_003760"
     CDS             14600..15460
                     /locus_tag="KRN00_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829532.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASISDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     CVEERDNRQN"
     gene            15718..17832
                     /locus_tag="KRN00_003761"
     CDS             15718..17832
                     /locus_tag="KRN00_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBH1829533.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLEKVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMAEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTGELTQLIDM"
     gene            18373..19326
                     /gene="blaCDD"
                     /locus_tag="KRN00_003762"
     CDS             18373..19326
                     /gene="blaCDD"
                     /locus_tag="KRN00_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBH1829534.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNNKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLINKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGYTNFKKEHINILRDIMKIDVNDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
BASE COUNT         7605 a         2240 c         3652 g         5908 t
ORIGIN      
        1 tattaatata atgtacataa aaaatatcat aaatatatga taagataaat acaatagcaa
       61 cattttatta attttttggg tttttatata tttaggtact ggggtgatat agttgaacca
      121 agagatattt tttaaaataa tgaatgaaat attggaaaat attgatgaag gggtacattt
      181 tgttaataaa gacgggaaaa ctataatcta caataattct gtacaaaaaa tggaaaaaat
      241 gaacagacac gatattttag ccaattcatt ttttgatata gtcaacaaaa tgaaaataaa
      301 caggagtaca ctattagaag ttttggaaaa aagggaagtt atcaaagaca atattcagaa
      361 atatctggat aaaaatggaa aagagataac agcaattaat actacaatac caattgatat
      421 taaaggcgag tttgtagggg cacttgaaat atcaaagaat atgacaacga tagaaaattt
      481 actaaataga aattataaaa aaaatttagt caataaagtt agtagtagac aaaaaaaggg
      541 ttatgaattt gatgatattt taggggaaag taatttgatt aaagaagcaa tagaaaaatc
      601 taagaaagct tgcaagtctg atgcttcagt atttatatat ggtgaaactg gaacgggtaa
      661 agagttattt agccagtcca ttcactatgg aagtaatagg agaaactatc catttatagc
      721 acaaaattgt gcagctttgc cggaatcact attcgaaggt atcctttttg gaactagcaa
      781 gggaggattt acaggagcaa tagataggcc aggtttattt gaacaagcta acaaagggac
      841 attgttattg gatgagataa attccatgcc tattatgtta caggctaaac tattaagggt
      901 tttacaagaa ggttatgtaa gaagggttgg aggaactaag gatataccta tagatgtaag
      961 aattattgca acgacaaatg aaagtccaaa ggtaatttta aacgagcata aaatgcgaaa
     1021 agatttatat tataggctta acataattca tataaaaatt cctcctctta gagatagaaa
     1081 agaggacata cctctattgt gcaaaaaatt tatttcaaag tataataaaa agttaaataa
     1141 aaaagtggta ggaatttcag atgaagctat taaaatttta aaaaattacg attggcaagg
     1201 taacataaga gagctagaaa acataattta ttgtactatg agtatgatgg aagatgaggt
     1261 acaaatagaa acaagtatga ttaatctaaa cgactattac aatcttaaag agaataaaga
     1321 gagtaacaat tattctttaa acgatttgga ggacaaaaca cttagtaaga ttatcagtga
     1381 gatagaagaa aagtatatat atgaatcatt agaaaaggca tcatacaata taactaaagc
     1441 tgcatcaatt ttaggtatga ataggcaaaa tttacagtat aaaataaaaa aatataatat
     1501 caaaatatta taaataagca agataaaaaa acaaaatcaa agtaaaataa aaaagcaaaa
     1561 tagaggagca aaattattat aaaagagcaa aatattttgc tctttttttt atttctcata
     1621 agaaatatta ttttttattt atgaaaatac ataataaaat aattatagtt tcaacgttcc
     1681 aataaatatt tgctttaatt ttaaagttgg cacgatttat gctttaacta attattgaga
     1741 atatataaat ttttaggagg gtgtatatat gagaaaagta agagtaggaa tatggggatt
     1801 tggagctatg ggaataggta tggctaatat gattctaaag aaagaaggta tagaaatagt
     1861 atctgtttgt agtagaagta cttcagggaa aagtatgtat gatgttttag gaattgaaag
     1921 aggagaaaga ccagaagtta ttatcaataa aaattatgaa gaagttttta gagaaaaaag
     1981 tgtagatgtt gttttgttag caactgattc atttactaaa aaggcttttg ataaaataat
     2041 tttcttatta aatagaaaaa taaatgttat atcaacagca gaacaaatgg catatccaca
     2101 agctgatgat gcagatttag ctaaaaaaat ggatgaagtt gcaaaggaaa atggagtaag
     2161 tatacttgga acaggaataa atccaggatt tgtattagat ttactagtat tggcactttc
     2221 aggtacttgt gaagaagtta ctagtataaa agctaagaga gtaaatgatt tatctccatt
     2281 tggaaagtct gttatggagg aacaaggtgt tggagtaaca agggaagaat ttataaaagg
     2341 tgtagaagat aagactatag caggtcatgt aggttttgta gaatcaataa atatgatagc
     2401 tgatggatta ggttggaaat tagataagat agaacaaaca aaagagccaa taatgactac
     2461 agtagataga aaatctaagt acggagaggc attggctgga aatgttgctg gttgtagaca
     2521 atgtggatat ggatatgtaa atggagaagt tttaattgaa atggagcatc cacaacagat
     2581 aataccagaa gcagaaggta ttaaaacagg agactatgta tcaataaaag gtataccaaa
     2641 cattgattta caaataaatc ctgaaatacc tggaggagta ggtacttatg caatgatagt
     2701 aaactctatt ccattaataa taaatgctag accaggtctt aaaactatgt tggatatacc
     2761 agtacctaga gcaataatgg gagatataag aaatcagata gaagttgaat tggaagaaga
     2821 atcaaaggct aattagtaag ataacagata actaattagt aagatagcaa ctagctaatt
     2881 agtaagataa cagttagcta attggtaaaa taatgtttaa tttaaaataa cagtaaatta
     2941 attagtaagg caatagtcaa ttaataaggg gatgaaaaaa tggatgctaa aattaatgat
     3001 tgggttatta tacacaatat agtattgact ccagaagaaa gagctccaca agttccagag
     3061 gatactaaga aagtatcctt agaaatgtgg gttaaaggtt ttatacaaag tgatgcttct
     3121 ataggcgact tagtagaagt taaaacaatt acaggtagac ttgtaaaagg taatttactt
     3181 aaaataaatc catattatac tcatgattat ggtaaatgta taccagagtt actccaaata
     3241 ggaatccaag ctaaagaaat attatttgga ggtgtatata atgaataatt caacatcaat
     3301 gaaagatatg agttatcaag ctgttatggg aagaaataac gaaataatga aaaatgcaat
     3361 cggattggat tattcttctt ttgaacaaga gggaataggg tttgattatg agaaaatgat
     3421 gagtgaaaca ggatatacat tacaagatat tgaagcaatt caatcacagt atgctgttgg
     3481 aaatactcct ttaatagagc ttaaaaattt gactaaatta gctagaaaat gtgctaaaga
     3541 aggtaaagga gctagaatat ttgtaaaaga tgaagcaatg aatgcatctg gtagttttaa
     3601 agcaagaaga gcagctactg cagtatatca tgccaaacaa atgggatata aaggtgtaat
     3661 agcagctacc agtggtaact atggtgcagc tgtagcatca caagcggcaa tgcagggatt
     3721 aaaatgtata atagttcaag aatgttatga ttctaatggt gtaggtcaac ctgaaattat
     3781 agaaaaagcg cgaaaatgtg aggcatatgg agcagaagtt gttcagttaa ctgttggacc
     3841 agagttattt tatacgttct tagttttatt agaagaaaca ggctatttta acgcatcatt
     3901 atattcacca tttggaattg caggtgtaga aactttaggt tatgagttag ctatccaatt
     3961 tagagaaaag tataaaaaag accctgatat agttgtttgt acaaatgcag gtggtggtaa
     4021 tcttactgga actgcaagag gattgataaa agctggttct attaatacta aagtagtagg
     4081 agcaagtgta gatttaaaag gattacacat ggctagtgat aatcaattta ataaaaaatc
     4141 atttacaaca ggacatacag gttttgggat accatactgt acatggcctg ataggtcaga
     4201 tgtacctagg tctgcagcta gaccacttag atatatggat agatatgtat tagtaaaaca
     4261 aggagaagtt ttttatacaa ctgaattatt ggcacagcta gaaggtatag aaagaggtcc
     4321 agcaggaaat acatctttag cagcagcatt ctctttagct caagagttag atgaagataa
     4381 agttatagtg gtacaagaaa cagaatatac gggtgcaggt aaacatatat gtccacaact
     4441 tacctttgca agagaaaatg gaatagatat aaaatttgga aatccaagag aagaaattgc
     4501 aggagtaaac ttaatattac cagaaagacc agaattattg aaatgtgttg atattgatat
     4561 gaataaaata agaaagtcat ttataaaaaa ttgtatatct aataatcaca ttgataatat
     4621 tgataagcta agtaatcgag atatagaatt tttaatggaa gaagtaaaaa gttcaagaga
     4681 ttttgttgtt gatgtattaa ataatttata gtaattattg ttttttaatt taatataaaa
     4741 taaaaattca gaaaattcga ttaaagcaat acgaatggag gaatgttcat gaaaaaaaga
     4801 gaggatgatt ttgaagttag aagaaaacat cttcaagaac tgagtgatga tgagttaaaa
     4861 gaaaggtttt ggagtttagc tacccagata gtagaaccaa tgatagaact tggtaaaaag
     4921 aatacaacac catcaataga aaggtctgtc ttgttgagaa tgggattttc ttctcttgaa
     4981 gtaaaaccta ttttagaagg ggttatggaa agaggtctta taggtaaagg agcaggtcat
     5041 gtagtttata aattggctaa atctaaaaat ataacggtta gagaagcagg tttgttatta
     5101 gttaagggtg aatattggga tgaagttaca tgtttattta gagaaggggt agaatcatgt
     5161 taaaggaaaa taaaaaattg gatatagact atatattaaa agatttggat aaatataaac
     5221 caaaacgaag aggttgggtt tggagagaac acttggaaaa tcttgaaatg ggacctttta
     5281 aatataaaga ctgtacaaaa cctttaaaga agagtgtagg gctaccatca tctaagtatt
     5341 tcaataatat agaccctcaa ccaagtccag ttattactac tgaaatagct tctggtagat
     5401 ttgaggatga tataagaaga atgagaatgg cagctcatca tggagctgac catctaatgg
     5461 ttatcagaac tgctggacaa tcacattttg atgggcttat agaaggaact ccacaaggta
     5521 taggtggagt tccaataaca agaaaacaag taagagctca aaggaaggct cttgatttta
     5581 tagaagaaga agttggtaga cctattaatt atcattcata tgtaagtggt gttgctggtc
     5641 ctgaagtagc agtaatgttt gctgaggaag gagtcaatgg agcacatcaa gacccacaat
     5701 ataatgttct gtataggaat ataaacatgg taaggtcttt tgtagatgct tgtgaggcaa
     5761 agaaaataat ggcttttgcc aatatagctc aaattgatgg agcacataat gctaatgcta
     5821 ctgctagaga agcatggaag gtaatgcctg aacttatggt tcaacacgct ttaaactcta
     5881 tattctcaga aaaaataggt atagataaaa ataatatatg cttatcaaca gttccaccaa
     5941 cagcacctcc agcaccatgt ttaaaaatag acttacctta cgctgttgca cttagagagt
     6001 tatttagtga ttataagatg agagctcaaa tgaatactaa atatatggaa tcatcaacta
     6061 gagaagcaac agttactcat gtattaaact tattaacatc agtattaact agagctgaca
     6121 tacaatcaac tataacacct gatgaaggta gaaatgtacc ttggcatata tacaatatag
     6181 aagcatgtga tacagcaaag caagctttag ttggtatgga tgggcttatg gatatgatag
     6241 aacttaaaga tgtcggtgaa ttaagagaca aagcaagaga acttaaagaa agagctgtat
     6301 tatatatgga agaaatatct gaagttggtg gatattttga atctgtggaa caaggatttt
     6361 ttgttgattc tggaaattat ccagaaagaa atggtgatgg aatatctaga aaaataaaag
     6421 gtggagttgg tgaaggtact gtttatgaaa gagaagaaga ttatttagca cctgtaactg
     6481 ctcactttgg atacaataat gtagctcaat atgatgaaaa tgctatagat aatccatcaa
     6541 tgttaataga tggatgtaca tttgaaaatc cagacaaaat aatatatatt gatgagcttg
     6601 acgattttga taatgtagaa aatagactaa aagaatcata tgagtacaga aatggaacta
     6661 aaattaagcc tgaaatggaa tggtgtgcag atggaattgt aatgataaca atgatgcttc
     6721 ctactgataa aagaacagca gagtttgcag ctttggaatt tgtcaaaaaa atgaacttac
     6781 aagaaattga ggtcataagt agagaagtta tgcatgaatc tgaagggact agaatagaag
     6841 tgaaaggaag agttccgttt gatatagatt taaacaattt agtaatacca gaagaaccta
     6901 aggtactaac tgatgaagaa ataagagcag atatagaaga aaaacctatg aaaatagttt
     6961 cagctacggt tggagaagat gaacattcag ttggtttaag agaaataata gatataaaac
     7021 atggaggtat tgaaaaatat ggcatagaat gccactatct agggacttct gtacctgtag
     7081 aaaaattggt agatgcagcg attgaactga atgcagatgc aatacttgca tctacaataa
     7141 taagtcatga tgatattcac tataaaaaca tgaaaaaatt acacgattat tgtgtagaaa
     7201 aaggtataag agataaagta atgattgcgt gtggaggaac acaagtaaca cctgaaatag
     7261 ctgttgaaca aggcatagat gctggatttg gaagaaacag caaaggcata catgtagcca
     7321 ctttcttagt tgaaaaaaga agagaaatga gtaataaata atggaaaata gcaaagtttc
     7381 tttaaaaata gatgtgttgg tagctgaaat tggaagtact actacagtgg taaacgcttt
     7441 ccatgatatt aatactaaca atcctatatt tttgggtcaa ggtcaagctc caacaacagt
     7501 gtttgaaggt ggcgatgtaa gaaatggctt atcaggtgct attaaagatt tagctaataa
     7561 attatctgta gatgatataa agtataatga tatgtttgca acttctagtg cagctggtgg
     7621 attaaaaatg actgttcatg gattagtcta tgatatgaca gtaaaagcag ctaaagaagc
     7681 agctttaggg gctggagctg ttattcgtca aataacatca ggtagaatta aaagaactga
     7741 tttaaataaa ataaaagaaa taaacccaaa cataatttta atagctggtg gagtcgatta
     7801 tggagaaaga gatacagcta tttataatgc agaaatgata gcttctatga atctaggcat
     7861 accagttata tatgctggta atgttgaaaa tcaagaggaa ataaggttaa tatttgaaga
     7921 tactaattat aagctttata taactgaaaa tgtataccct aaaatagatt tattgaatat
     7981 agaacctaca agaagaatca ttcaaagtgt atttgaagaa cacataacta cagcaccagg
     8041 aatgaaatac attaaagaaa tggttaatga aaatattact ccaaccccag gagctgtaat
     8101 ggaagcttct aaacttttat ataaaaatat tggagattta ttaactctgg atgtaggtgg
     8161 agcaactact gatgtacatt ctgttacaga tggaagtgac tatattaata aaattttggt
     8221 taatcctgaa cctactgcaa agagaagtgt tgagggggat ttaggtgtat atgtaaatat
     8281 gaagaatata gtagaagtta taggtaaaga aaacttacaa agtgaactat ctatagatat
     8341 tgatgcagta atagagaatt atcctccaat accaaaatca aaagaagaaa tattatttgt
     8401 tgagaggttg acaaaagaag ctgttgttaa agctatgcta agacattcag gaaaaataag
     8461 aaatatctat ggaacaactg gaaaagtcaa aattgcagaa gggaaagatt taacagaagt
     8521 aagatatata gttggtacag ggggagcact tactaggctc cctagtagaa ttgaaatatt
     8581 agataatatg ctcaaataca ataaaaataa tgaattacta tttccaaagg aaaaaacaaa
     8641 gatattaata gataatgact atattatggc atctatgggt gttttatcta aaaaatatga
     8701 agaagcatct tttaagctcc tgttaaaaag tttgaatttt gaggaggaaa gattatgtat
     8761 cctaggttag aaatagatat agaaaagtta aagcataatg caaaattaat ttcgcagatg
     8821 tgtcatgaaa gaaatattaa gatatctttt gttactaaat cattttgtgc acaaaaagaa
     8881 atagtagaag aaatatgtag tgaaggaata gaccatatag cagattcaag aatacaaaac
     8941 ttaaaaaatt tacaagatat aaatctacct aagatattga ttagaatccc aatgttaagt
     9001 gaattagaag aagttatcaa ttattgcgat attagtttta actcagaatt aggaacaata
     9061 aagaaattaa atgaattatg tgaaagtaaa aatattattc ataagatagt tcttatgttt
     9121 gacttaggcg atttacgaga aggatacttt tatgaagaag acttttttag taatgtaaga
     9181 gagatagtaa gattaaaaaa tattgaaata attggtatag ctacaaactt aacctgttat
     9241 ggagctatta taccatctag ggaaaatata ggcagactgg taagtatagc aaaaagaatg
     9301 gaagaaaaat ttggaataaa tctagaaata gtatctggag gtaattcaag ttcgattcat
     9361 ctgttgataa ataataatat gccagaaggt attactaatt tgagaatagg cgagtccatt
     9421 ctacttggta gagaaacggc atacggtgaa aatataaatg gaacatatca agatgcattt
     9481 aaattaatat gccaagtagt tgaatgtaaa gaaaaaccat cagttcctat tggagaaata
     9541 ggagttgatg cctttagaaa taaacctgtt tatgaagata agggaatctt aaaaagggca
     9601 atcatagcta taggtaaaca agatataaat attgactctt taattccaat agacactgat
     9661 ataaaaatat taggggcaag ttcagaccac atgatactag atgtaagtaa cacaaaatat
     9721 gattataaat taggtgacaa tttagaattt ttattaactt atgggggtat catgtcatct
     9781 agtacaagca aatatgtttc aaaaaaaatt atagtgtagt gtttaaataa ttaggaggaa
     9841 actattttat gaaagagcga gaatgtagaa aagcaagtct gtttgatgca atgataccaa
     9901 ttacttgttt gatattattt ttaagtctag gagtattagt gtatggttca tcacctcatg
     9961 taccactaat aggagcagca gcagtagcag gacttgtggc tgtatataga cttggattta
    10021 aatggaaaga gttagaatta agtatgttta atagtataaa gatggcaatg caagcaatct
    10081 taatcataat tataataggc gtacttatag gaacttggat agtaagtgga gtagttccat
    10141 gtatgattta ctggggacta aaaattttat caccaaatat ttttttagta gcatcaacat
    10201 tagtctgtgc aatagtatct cttgcgacag gttcatcttg gagcacaatg ggtacagtag
    10261 gagtagctct tttaggaatt ggtcaaagtt taggtatgcc aattggatta atcgtaggtt
    10321 ctataatatc tggagcttac tttggagata aactatcacc tttatctgaa acgactaact
    10381 tagctccagc aatggcagga acagatttgt ttacacatat aaaatatatg ctatattcga
    10441 ctataccatc attattaatt tgtttagtaa tttatggtgt aattggaatg aagtattcag
    10501 gtcaagcact agatataaaa caaatagaat taattaggtc tacattagat tctacattta
    10561 atactttatc accagtatta ttattagctc cagcaatagt aattggattg gttgtattta
    10621 aagttcctgc tataccaggg cttatagtag gtgctgtatt gggagtattg tttgcagtag
    10681 tttttcaagg agaatctatg aatacgatat tagatgcagc acaaaatgga tatgtttcgt
    10741 caacacaaat acaggaggta gatgctttat tatctaaagg tgggattatg aatatgatgt
    10801 ccactgtatc cttaacaata tgcgctttat ctcttggagg tattttagaa aaaacaggta
    10861 tgcttgaagt agtagcatct tctttactaa gattagcaaa gggtgtattt ggaacagtat
    10921 tatgtactat ggtaacttgt acaattacca atataatagc aggtgaacaa tatctatcta
    10981 tagttatacc aggaagaatg tataataagg aatataaaaa gagaggtata catcctaaga
    11041 tgttgtcgag agctttagaa gatagtggaa ctttaacttc tccattagta ccatggaata
    11101 catgtggggc gtatataaca gcaacattag gtgtatctgc actaacatat ggtccatacg
    11161 ctttattaaa tattataaat ccaatagtat ctttagtatt aattgcatgt aagtttaaaa
    11221 tagcaagaat agaagatgaa cctgaaactt gtttaaattt tgatgtttga tattttaatt
    11281 gtttgtataa attttttata gaaaaagatt tcttttagac ttgcctaaaa attaggcaag
    11341 tcttttaagt atgttctgat tataagagca ctgcgtgaca agaatgatga gattattttt
    11401 gctatacttt cgatataaga aatggaagga ggttatgttt tatattcata tgaaataatt
    11461 agttacacag tgaattttcg tataatttgg tataaaaaga ttagaaatga aaataaagta
    11521 atggaggaat aaaatgacta gaatatccaa tataacaata gctgaacaat ctgagtactg
    11581 ttttttggca atacgaaaaa caattgactt tatggtagag ttttcagagt tttcaaaaca
    11641 aagttttgaa aaaatttcta aatatctgga ggagagagga attttatctt caggagcacc
    11701 gattgtatgt tttcataaca tggatttagc aaaattggat gttgaagtag ggtttcctgt
    11761 agccacttat atagatggga aaaatgagat tctacaaagg attgttcctg cacagaaaat
    11821 aataactgca attgatttag gaccttatga attacaagac cctactttag aagacttatt
    11881 ttcatgggca aatagcaatg gatataaact tcatggcgat atatattacc agtatttaaa
    11941 tgatatcaat cgtccagcta gtgaatatct tacgaaaatg atgttaccca ttatatagaa
    12001 agttaaagat tatcgtttgt tagttgataa ttagaagaac atttactgct actacataaa
    12061 ttttatccta aataatatca aggtgattta atttatgtat tctaatgtaa ctgtagataa
    12121 tcaatttata actaacttag tgtaatttag atttaattta ttattctaat gtaaccccaa
    12181 tatattgtta aggtctactt aagatgctca aaaggctatg cttaatttat tgttatataa
    12241 tttgtagagt ggtataattt agaagtgata ctatatagat atataggggg aaaatatgaa
    12301 aatatatgat atattaacac gtttttatat tcaagatata gaaaaagcca taccttttta
    12361 tgagaatctt ttaaaagaaa aatgttcttt gcgtttttct tataaagaag ttgggttgga
    12421 attagcgcaa ataggaaatg ttttactatt atctggttct gatgatgctc ttaaaccatt
    12481 tatagaaaca aaatctactt ttatggttga ttctgttgat gaatggagaa gttatctatt
    12541 ggataatgga gcagttgtag taagagataa gaaaaaagtt cctacaggat ataatatgac
    12601 attgagacat ctagatggta caattataga atatgttcaa catacaaagc aggattagtt
    12661 aaaaatatat tttactactc agtaactaat tataatatat tcttcggaaa actggaggta
    12721 attttatgaa cgaaaaatgg ttggaatggg cgatagaatt gcaaagcatt gctcaagccg
    12781 gaataactta tgggaaagat atatacgaca tagagcgata tgagagaata cgagaaattt
    12841 ccgccgaaat gatagcatat aaaactgaca tatcaacaga aaaagtaaga aatctttttt
    12901 gcaatgaaag cggataccaa actccaaaac ttgataccag agccgttatt tttgaaaatg
    12961 gaaaaatact tcttgttaaa gaaaatacag ggaagtggtc gcttccgggt ggttgggttg
    13021 aagtaaattt atcagtcaag gaaaatacta ttaaagaggt caaagaagaa gctggattag
    13081 atataaccgc cgacaggatt attgcaattc aagaccgtgc gaaacacaat ttacctatat
    13141 atgcttacgg agtatgcaaa atatttgttc tttgtaccgt tatcgggggt acattcaaag
    13201 aaaatataga aactacggag ttttcttatt tctccgaaaa tgaacttcct gaactcgcca
    13261 cagaaaaaaa tacagaagaa cagattaaaa tgtgctttga agcatgtcgt acagacactt
    13321 ggacagtgat tttcgattag gttaattaag gagaaattaa tggattacaa agaaatcgtc
    13381 tttgatgtag acggcacatg gattgatact gaatacgcca ttttacactc tctacaagac
    13441 acgataaaac aaatcaatag aaagataatt cctatcaaag aattgtcttt tgctttagga
    13501 ataacaggcg aggacgcttt acgttatttg aaaatcgaag atataacaat tgctctatca
    13561 atgtgggata ggaatatgga aaagtataag aatacagttc ttgtgttcaa agaaataaag
    13621 gaaatgctta ctgaactcat aaaattaaat attggcattg gaattgttac atccaaaact
    13681 catgaagaat ttagaaacga ttttctgagc tttgacatag caccatactt taatactgta
    13741 gtatgctcca atgacactct agagcataag ccaaaagcag taccattatt gaaatacatg
    13801 gaactgacaa aatgtcaaaa caacgaactg ctttatattg gggatagtat atatgatatg
    13861 caatgtgcct atcgtgcaaa tgttgatttt ggactggtaa aatggggttc tggcgataga
    13921 gtaagcgctg taatatcttt taccacacca ttggatttga taaggcaact atctgtatca
    13981 agcaactaac aatcatagaa aatagcaaag tcagccgagc cagtcaatgg tcaagatgaa
    14041 cggcgcattt catgtgccac cgttgacagc cccgtctgct tttgctgacg ggcaatcaag
    14101 atgggaaagc cctaaaatgg cttcccgcct atttcaattt tgagaggaaa atccgtctgc
    14161 tttttcgtga gtgtggctac aagttggagc gtaggacgag ggacgggagc tttcatatac
    14221 ccatgtatgc tgctgaaacc cgccttgcgc ttgtgacttc acgctatgca atcacagccc
    14281 tgttttcctg ccgcttcaaa tgcccttgcc ttccctgatg gcaacggcat ttttacggca
    14341 acgccaacag agcgtataac acactacact ttgcaagtaa agtcgtgtgc caaggggaaa
    14401 gcccctttgg aaattccaga caacaaaaca gtctgaacac ctcgcgcttt ccctgtgctt
    14461 gatgttcagc ttttatttgt tgtaagcagc cccatttcgt ggtctgcgtg tagttccttg
    14521 taaactgacc taagattcat taaatataac taagttataa ttaatataat gttgcatgga
    14581 taaaaggagg gaagctgcaa tgtcttacaa agtaattaat gtcataactg ctattgacta
    14641 tatagaggag catttatcag aaaagctgga tttagatata gttgctaatg ctgttcatta
    14701 ctcaaaatat cacctgcata gaactttcac aacttctgtt ggcctaacaa tgcatgatta
    14761 cataaagcgg agaaagttga cagaagcagc aaaattattg gtattttcaa agaaaccaat
    14821 tattgaaatt gcattgatag ctggatatga aagtcaacag gcattcactt ctatatttaa
    14881 agctatgtat aaaaaatctc caaataaata taggaaagaa caagaatttt atcctttgca
    14941 gctaagattt gttttgaaaa aagataacct attttcaaag aatgtactag agttggaaaa
    15001 agaaattaaa cttgcaagta tatctgacat accattatgg atgaatttag tgagattagt
    15061 catagatgga tttccaaatt tgcaagagga agaatatata tatcaattag aacagtatat
    15121 tttagaagaa agagctttaa tattaaaact taataatgtc gctattgcaa atatggtgtt
    15181 taatagagaa actagaagta ttgatttttt tggaatacat ccacagtatc gtaattcaga
    15241 cattgcacaa gtgtttttga agaaagttat tgaagatttc ttgatagata cagatatttc
    15301 aattactacc tttcgagagg gtgacaaagc tgatacagga catagagata tgataaagaa
    15361 gttgggcttt gcagaagcag aattgcttgt ggaatttgga tatcctactc aaaaatttat
    15421 tcttccttgt gtagaagaaa gagataatag acaaaattaa ttgtagatta aatgaaaagt
    15481 ttaccacata ttttttgttt gaattatttt atatataaga gcatttctgc ttttaatgta
    15541 ttttgcttgt aagtgtactt atggtaataa atatagaaag atttagtttt ttaaaaaagg
    15601 aactttaaag ctaaaaagct aacatttaag ttaaatagca agaatgatta aaaactccaa
    15661 aacacaatta agtataatga ttcagtgtaa gtacttaatt aacaaaggag gatttaaatg
    15721 tctgaaaata aacaagtagt aaattgcgat attattgcat ctaattctaa acataatatg
    15781 tgtgaatatg atgcagagtt attaactttt tttccagatg agattgcaca tctaatagag
    15841 ataaataaca agctagacaa tgcttttaag aaagctgaaa atcttgttga caagcttgat
    15901 aaggattata tggacgctaa aatgtatatg gtaaaaaatc gtggtgaaat agacccacat
    15961 gaaatgtttc aaaatgaaca aggactaaaa caaatagata actatggggc ttttatggta
    16021 aaagttcgag ataagattaa taaaatcaaa gattctccat actttgctag aatagatttt
    16081 aggctgaaag atatggatga tgaatctaag tattatattg gtagatttgc atttgattat
    16141 gaagatgagc ttataatact tgactggcgt tctccaattg ccagtatgtt ttatgattat
    16201 gaaatcggaa aagctggata tgatgctcca ataggatggg tggatggaga aataacaaga
    16261 aaacgacaat ttaaaattaa aaatggaaaa ttagaatatg cactagaaag ttccattaat
    16321 atacaagatg atattcttca aaaagaactt agtcacactt cagatgaaaa aatgaagtca
    16381 atcatttcaa caatacaaaa ggaacaaaat caaattatta gaaatgataa agctgataca
    16441 ctgattattc aaggggtagc tggttctggg aaaacatcta tagcattaca cagaattgct
    16501 tttcttcttt atcgatttaa agataaaata tcagcaaata atgtaattat cctatcacct
    16561 aataaagtct ttggagacta tatttccaat gtccttcctg agcttggaga agagccatta
    16621 tgtgaattaa gttttgaaaa tatagcagag gtacaattag atagagttat taattttgaa
    16681 agtgagaaag acccattaga aataaatgat gctaaatggt ctgaaagagt gcgttttaaa
    16741 tctacacttg attttgtaaa acttattgat gattatataa aacaaatgcc aaataagatt
    16801 tttattccaa aagactacac ttttggaagt tttacagcta aaagtgactg gatacagagt
    16861 agatttgagg catataacag atatccagtt aagaagagat tagaaaaggt agctgaagac
    16921 attcattata aatttgaatc agataatatt atggaagaag atttaccaaa ggtaaaaagt
    16981 atacttaaaa gtttgaatgg aatgttgaca ataaaaaata ctcttacact atataaggat
    17041 ttctttaaac aaatgaatat atcaaacatg tttgtgatgg cagaaaagaa aacacttgaa
    17101 tggtcagatg tatacccatt tatatatatt catgctgcat atgaaggtat acaagaagat
    17161 aagattataa ggcatattgt tattgatgaa atgcaggatt atacacctat tcaatatgct
    17221 gtaataaact tactttttaa gtgtaaaaag actattcttg gagattttgg acaattggtt
    17281 aatcctaatc atactcatac attagatgat atgaaacagc tatataatga tggggaacta
    17341 gttatgttga acaagagtta ccgttctact tttgagatta ttaatttcgc caaaaagatt
    17401 caagacatat cttcattaga gcctattgaa cgacatggtg aagaaccagc tttattaaaa
    17461 tgtaataacg agcaagatga aataaataag ataaaaatag aaattgaaga atttaaaaag
    17521 agtgataatg cgactcttgg tattatatta aagacagata atgacgctaa agctgtatat
    17581 gatgcgttaa gagaagaata tagtgttcac ttaatatctt ctgaaagttc tagctttaca
    17641 aaaggagtat ccataacttc tattaaaatg tcaaaaggtt tagagtttga tgaagttatt
    17701 gtaccttcag taaataataa aacatattat agtgattatg accgcagttt gttatatatt
    17761 gcttgtacac gagctatgca taaacttaag ttgacatata ctggtgaatt gactcaactt
    17821 atagatatgt agattatata cttattatgt aagtgtttac ttatataaat ataacctgta
    17881 aataaaattc attaataaat caataaaaac aatatttgta aaagtaaaag ctataaatta
    17941 tatattaaat tttataattt atagctttta taatactgct tatcttaatc ctcccaatag
    18001 caaaataatt ttaaacatgc catattttat aaatgtaata acaattatac aattaaaata
    18061 actttcccaa actaacttga catttaaaac ctactattgt aatatttaaa tattacaata
    18121 gtaagtttta aatgtggaat caattattat atcacaaatt aaaaggagga caggatgtta
    18181 ttaatagtta cctaattatc ttcgcaatag gtttaatcaa cataattgta ctaggtgaag
    18241 aaaatataag agatacagct attcatttag tcttgtttct tataagtaga acctagattg
    18301 gagtatatta caaataatgt ctactatttt aatagtaggt tataaattta aatatgggag
    18361 atgatataaa ttatgaaaag aaaaaagaat tttatttgga tagctatctt attggttggt
    18421 gtagttatgg taatgtatta tgtagggaaa aaacataacg atataaatca aaaaactgat
    18481 aagaattata taaaatctga attaaataag tctgaattaa ataaatccaa aattgaaaac
    18541 aataataaaa acaaaaaaga aaaaattaat atggttgact atagtgattg ttttgaaggt
    18601 attagtggag gagctatttt ttataatact aaaaataaag aatataatat atataacaaa
    18661 gaattaattg aaacaagaag gtcaccatgt tctactttta aaatagtttc aactttaatt
    18721 ggtttagaaa aaggggtaat aaactcaaaa gaatcagtta tgggatatga tggtacagag
    18781 tatccaaata aaaattggaa taaaaatctt agtttagaag aggcatttaa ggagtcttgt
    18841 gtttggtact acaaaaaatt gataaataaa gttgatgcta aatctgtcca aaacatttta
    18901 gatgatttaa agtatgggaa ttgcgatatt agcgaatggg aaggagattt aaaaaatgga
    18961 aagggacatt taaatggatt ttggttagaa tcttcattac aaatatctcc aaaagaacaa
    19021 gtgcaaacaa tggcaaaaat atttgaggga tatacaaact ttaaaaaaga gcatattaat
    19081 attttaagag atattatgaa aatagatgta aatgataaaa acataaatgt atatggaaaa
    19141 actggaacag gatttgatga aaaaaataaa cgtgtggatg catggtttgt tggtatgcta
    19201 gagcgtgaag gtgacaccta ttattttgct attaaatcag atgattccaa taaagaaatt
    19261 acagggccaa aggtaaagga aattgcaatt aatataatta agaaatatta tagtgtaagg
    19321 gaataaactt aattttattt gtaaatatta tttacctata gtctgtaata tttattaaat
    19381 aattttacta aattgagtct atata
//
LOCUS       DAEQAF010000236        11280 bp    DNA     linear   BCT 17-JUN-2021
DEFINITION  TPA_asm: Clostridioides difficile strain WA814
            SAMN13376495-rid12478723.guided.111, whole genome shotgun sequence.
ACCESSION   DAEQAF010000236 DAEQAF010000000
VERSION     DAEQAF010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN13376495
            Sequence Read Archive: SRR10518337
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 14-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001069529.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001069529.1
            Genome Coverage       :: 338x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/15/2021 01:19:34
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,777
            CDSs (total)                      :: 3,689
            Genes (coding)                    :: 3,648
            CDSs (with protein)               :: 3,648
            Genes (RNA)                       :: 88
            rRNAs                             :: 7, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 7 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 41
            CDSs (without protein)            :: 41
            Pseudo Genes (ambiguous residues) :: 0 of 41
            Pseudo Genes (frameshifted)       :: 19 of 41
            Pseudo Genes (incomplete)         :: 16 of 41
            Pseudo Genes (internal stop)      :: 17 of 41
            Pseudo Genes (multiple problems)  :: 9 of 41
            CRISPR Arrays                     :: 7
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11280
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN13376495-rid12478723.guided.111"
                     /strain="WA814"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="Australia"
                     /collection_date="2017"
     gene            418..756
                     /locus_tag="KRN00_003763"
     CDS             418..756
                     /locus_tag="KRN00_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829535.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            778..1095
                     /locus_tag="KRN00_003764"
     CDS             778..1095
                     /locus_tag="KRN00_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBH1829536.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1245..1922
                     /locus_tag="KRN00_003765"
     CDS             1245..1922
                     /locus_tag="KRN00_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829537.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2250..3017)
                     /locus_tag="KRN00_003766"
     CDS             complement(2250..3017)
                     /locus_tag="KRN00_003766"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBH1829538.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDITKEAKELEDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3689..4504)
                     /locus_tag="KRN00_003767"
     CDS             complement(3689..4504)
                     /locus_tag="KRN00_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBH1829539.1"
                     /translation="MVKLSDAKSWAIRMSEDGCAYKSIDNYKRSLKASFFMAIQDDCI
                     RKNPFNFQLSDVLEDTTEPKIALTPEQEMGLLSFMENDKTYCKYYDDVVILLETGLRI
                     SELCGLTLELDMKNKAIMVDYQLLSDTKIGYYVEVPKTTQGKREIPMTERAYQSFERI
                     VERRKNVKAEPIIVDGYQNFLFLKQDGLPKQATHYQSMLRALVKKYNKTHEDKLPKIT
                     PHTFRHTLCTNMANKGMSPNILQYIMGHKNITMTLGYYAHGSFSSSRAEMERL"
     gene            4605..5303
                     /locus_tag="KRN00_003768"
     CDS             4605..5303
                     /locus_tag="KRN00_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBH1829540.1"
                     /translation="MYKLSYVVRVSTKDLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFRATQTLGEHEDIYLGYNLDTGKNVYLK
                     PDLASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKNDSESLAIDILTFLAGISSRDSD
                     KFLQKNDNWKIIME"
     gene            5391..6011
                     /locus_tag="KRN00_003769"
     CDS             5391..6011
                     /locus_tag="KRN00_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBH1829541.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFFNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            6167..6949
                     /locus_tag="KRN00_003770"
     CDS             6167..6949
                     /locus_tag="KRN00_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBH1829542.1"
                     /translation="MTKTQQEMIQNVLEFSKRDSRIIGLAISGSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDFPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            7074..8000
                     /locus_tag="KRN00_003771"
     CDS             7074..8000
                     /locus_tag="KRN00_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBH1829543.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKKERCLISGIGLERFLVAVS"
     gene            8014..8463
                     /locus_tag="KRN00_003772"
                     /pseudo
     CDS             8014..8463
                     /locus_tag="KRN00_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8823..9230
                     /locus_tag="KRN00_003773"
     CDS             8823..9230
                     /locus_tag="KRN00_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBH1829544.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFLNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMEEH"
     gene            9232..9462
                     /locus_tag="KRN00_003774"
     CDS             9232..9462
                     /locus_tag="KRN00_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBH1829545.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINGILKHFEHYIIRLSQKTLF
                     DKYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            9843..10046
                     /locus_tag="KRN00_003775"
     CDS             9843..10046
                     /locus_tag="KRN00_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBH1829546.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLADENLDSGWVI
                     MNGNRIQIKRKQFEKIVDTLDVI"
     gene            10124..10477
                     /locus_tag="KRN00_003776"
     CDS             10124..10477
                     /locus_tag="KRN00_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBH1829547.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVDSFGKPQFVYSWK
                     LVSTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLHAKKNVLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10549..11181
                     /locus_tag="KRN00_003777"
     CDS             10549..11181
                     /locus_tag="KRN00_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBH1829548.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
BASE COUNT         4167 a         1580 c         1754 g         3779 t
ORIGIN      
        1 cctatatata attagattta aaaatgttta ccttaccaat ataatgatta aactcaaaag
       61 tcttattgaa aaattttcta tttacataaa ttgttcaata tataaaatag aaaatttttt
      121 taattttcaa aatatattct acatatctaa tatgtaatta caataaaaaa tgctataatt
      181 aacatattat taattcgttt tattattgta gtatggctat gaaattatga aaatatttct
      241 ctaattaaaa atatgattta tccatatttg tttattgtag atacagacta tacaaaaata
      301 aatagcactt atttcagtat aaaaacatat atagtctata tttagactaa aaaagtataa
      361 atagtctata taaaacaact taaactatga atataatcta aagtggaggg ataataattg
      421 gcaaatatag gaaaaataat aggagataga ataaaagtct atagaacaaa attgggatat
      481 agtcaagagt ttctagcaga aaaggcaggt ttacatccaa catatattgg tcagattgaa
      541 agagctgaga caaatacatc tatcaatatt ataatgaaaa ttgctactgc tttagacata
      601 ccacttgaat tgttatttgc aaatattatt acaacagaag gcgttgataa ctctgtacct
      661 ttagaatgtt atgaaatgat taataaatta actgaaaaag aacaaattgc aatgctagag
      721 ttaataaagt gcatcattaa atacaaagaa atataagtga gggaaatagt aacaataatg
      781 aattatatag gtaaaagact taaagaagaa cggaaaaaag caaatttaac ttcaaaagaa
      841 tttgcaaata tggttggagt atcgccttgg tatataactc aaatcgaaag tggtaaaaag
      901 aatccaagtc ttaaaacatt cataaaattt gtaaatatat taaatatttc tgcagatgtt
      961 cttataaaag atattacttc cactggaaaa acatatttag aaaatgatat aaatgaagag
     1021 ttaaaagact taaattcaag agaactaaat ctgatatcgc agattataga catcataaaa
     1081 aagaataaaa tataattctt tatattttat ataaaaaaaa aggttatttg aaataaataa
     1141 cctttttttg tctttttgtg ttaacattgt cttatagtgc taatgagtac tattagacca
     1201 tgttctatgg ccttatttta atataaaacg attggagata ggctatgatt gtgattgaag
     1261 gtagcgataa atttaagatt gcaaaagaat atattgatgt agaatatact ctttttagca
     1321 aagtaacttt taggtatgaa aagttgaaat ttaaagataa tgctgaatta gaaaaaatta
     1381 agatgtttaa atataaaaat ggctacatcc ctaataaatt aaacctttct tttggatatg
     1441 gattctcttc ttataaaaag caaataatta gagaaactgt agatacttta agattgacag
     1501 aaattttttc aagcgagaac atagaagata ttaaatttat aaaagatggt acaaaaaaat
     1561 tagaaattag catagagaaa gttgtgaaat ttaaacgtcg aaaaaaaaga aattatgttt
     1621 gttgctattg ccctgatatg tatagagaca taaaactcga caaagaatct atcaataaga
     1681 tatacaacag aaaaataaaa atagaaagag aagttaatat ttttgaagat gaggatgtta
     1741 taataaacaa aaaagtattg aagtttccaa agtcttggac aaagaatatg caaaaatatt
     1801 ggttaagtga aaataagtat cccatacatt ctactgtaat tgatgatgat agatataaat
     1861 gttgtaatgt acaatataca aaaaatagag tgataatatt atattacata tataaccatt
     1921 aatatacata attacaaaaa aataatgaca aatatacata atacaaatat atcttctact
     1981 ttagataaaa cagttattat gaaaacttac tatctataaa taatagaaat gctagtatac
     2041 catctataat ctaatgtcta gtaggtttta atggcatatt ttaaatatgc catagttgat
     2101 ttataagatt ttctatatca ctttcaaaat acacactaaa tagttgcttt tcagatataa
     2161 ttgcccaatt taaattttac tatctgaaaa gttttttata tttaatttat atattcaaaa
     2221 atatcatcta atatttctat ataattaatt taattaatac tcttatgtaa tagattaagt
     2281 actgaattta actctttaaa tgatatttgc cctggtgctg aaacactttt tgcagctcca
     2341 aaagtcaatg cagaaccaaa tatttcacca cacagtctac ttataacacc cattcctgac
     2401 attgacattg ttattattgg tctatctgca taaattttaa acatttcatt tgtagcttca
     2461 agtagcacta acacatcttt ttcattttgc ggcataacag ctattttggg taaatctgcg
     2521 cccaattcct gcattctaca taaacgagat acaatctctt ctttttttgg agttttatta
     2581 aaatcatgat tagatataat tactttcact tcttttttat gagcaaaatt aactacttca
     2641 tctatgacct catctcccat aaataactct acatctatta aatctactaa acctgtatta
     2701 gaaatttctt tattcaaagt agtataataa tctcttgata ttaatttttc tcccccttct
     2761 actacacttc taaatgtgaa taataaaggg atatcatgta tataacttct taattcatag
     2821 agaacttcct taacttcttt aatattttct acattctcaa aaaaatcaac tcgccactct
     2881 ataatatcca aacatgcatc ttctaactct ttagcctctt ttgtaatatc ttttttattt
     2941 ttcccaataa ttggtacaca aattttaggt ctaccttctc caatagtaat attttttact
     3001 tgaacttttc ttttcatatt ctcctccata atcagaaatt ttataggact ttaaattcta
     3061 ttttctgcac aatttaatta tacattaaaa atactataca ttataaaaat actaatttaa
     3121 aaataatttt tattctaatt cttaaaacaa tcccacatat tttagaaaag gtactctata
     3181 atatacaaac acttcttttt tacctaaatt tattttaaca ttctataatt ttcacaatat
     3241 tctttaaatt ttattcatat aaacaatatt attctggatg ctaatagaat taatctataa
     3301 atcatagtat aattatgcag aaataactcg aatttcacta cttatgaaga gattgaatat
     3361 taatgaatct aaatcatttg cattgcttaa gagttttgac taaagttgaa caccatacaa
     3421 aagtagctac tcaattgttt atgccccaac caagcttaag taatgttata tagattctcg
     3481 aaaaagaatt tagtatcttt ttatttgaaa aacttatatt aaatttgatt atcttttcat
     3541 aagttggtaa atgtcgatat atcctgtatc tacaaggagt atcggcattt tctttttgga
     3601 agatactttg cataagttgg catttaactg tataagaatg ccatcaaaag tagtaaataa
     3661 gtagtaaact ctagtcatac tactaggatt ataaccgttc catttcagct ctcgaagaac
     3721 taaatgaacc atgtgcataa tagccaagcg tcatagtaat gtttttatgc cccataatat
     3781 attgcaatat attaggactc attcctttgt tagccatatt tgtacagagt gtatgcctaa
     3841 aggtatgtgg cgtaatcttt ggtagcttgt cctcatgggt cttgttatac ttcttgacta
     3901 acgctcttaa catgctttga taatgagttg cttgttttgg taatccatct tgtttaagaa
     3961 ataggaagtt ctggtaacca tcaacaatga ttggttctgc tttaacgttc ttacgccgtt
     4021 ccacgatacg ttcaaatgat tgataagctc tttcagtcat tggaatttct cgcttaccct
     4081 gtgtggtctt tggaacttct acataatagc caatcttagt atcactcaac aattgatagt
     4141 ctaccataat ggctttattt ttcatatcca attctaaagt caaaccgcat aattcagaaa
     4201 tgcgtagtcc tgtttctaag aggataacaa catcatcata atatttacaa taagtcttat
     4261 cgttctccat aaaggataat aagcccattt cctgttctgg tgttagagcg atttttggtt
     4321 ctgttgtatc ttccaaaaca tcacttaact gaaaattaaa tggattcttt ctaatacagt
     4381 cgtcttgaat tgccatgaaa aacgacgctt tcagtgagcg cttataattg tcaatggatt
     4441 tataagcgca cccatcttca ctcattcgga tagcccagct tttagcgtct gataatttaa
     4501 ccatatcaat gctttttgca cctagtgggt cattgatagt atctatattt tgatttataa
     4561 tttatacatt tttttaaaaa cagactttta actgtaaaga atctatgtat aaacttagct
     4621 atgttgtccg tgtatctaca aaggatcttg acgagctaaa aaggcgttgt gatgaagtca
     4681 aagactttta cgacgactta tcaatcaagc tcgtgcgtcc ctttggggat atgttaggat
     4741 tgcatggcga atttattcct gtcagcaaac gttacatcaa tgattatatt caatatgtca
     4801 cttcggattt tttggctgga cttggtttta gagcgacaca aacccttggc gaacatgagg
     4861 atatctatct tggctacaat ctggacactg gaaagaatgt ctatctaaaa cctgaccttg
     4921 ctagtcaagg ggtaaagggt tctattacca atgcgttagc gtctgcgttt atcggttcat
     4981 tgggtggtgg taaattattc agtaacaata tgcttgttta ctatgcggta ctattcggcg
     5041 gacaggcggt catagttgac cctaaagcag aacgcggcaa atggaaagaa acgctaccag
     5101 aaatagccca tgagataaac attgtcaatt taaccagtaa tgatgaaaac aaaggattgc
     5161 ttgaccctta cgtcattttg agccgtaaaa atgattctga aagtttagcg attgatatcc
     5221 taacattcct tgctggtatc tccagtcgtg acagtgataa gtttttgcag aaaaatgaca
     5281 actggaaaat aataatggaa tagtttctat gtaaatatat ttttactatc ttacctaact
     5341 aattgaaaga tgatataatt taatcaaaga tttggtaagg agggatgaat atgcatttaa
     5401 ttgattttat gaatgaagat attaaaaaga agcttgttaa aaaaacgtat aaaaagaaag
     5461 agactattct ttttgctgag caagaaaatg aatatgtaat tcttatgatt gacggtattg
     5521 cagaagcatt catcttaaat gtgaaaggaa acatctcaac tattcatctt tatagaagtg
     5581 gtagtttttt tggagaaatg gaacaattta atgatgggaa aaaacccgtt gaaattgtcg
     5641 ctttcacaga ttgtaatgta tataaacttc atagagatga tttttttaac tggttaaggg
     5701 gagattttga agctacaaaa tttctgattc gagaaatatc tagtaaatta gttgtaaatg
     5761 ctgaattaat tgaagaatta tcatctttaa gtgttaaaga acgacttctg aggtgtatat
     5821 ccttacacta ttatagaagt gaattaaatc tgcttaccaa aaaacagctt gctagcgaag
     5881 taaacgctcc aattagaagc attaatcgtg ctataaatga atgtgtacaa gaacatctaa
     5941 ttgcttatga aaacaaaaga tttagtgtaa ttaatcagcg agaggtatta aagaatcttc
     6001 ctacaacata agtataattt caaaaaagta ttggataata attattcaat acttttttat
     6061 ttcgggtcaa gtgacctatt tttttttatt tcttcattat ataatactcc tatgcataat
     6121 tatgttggat tgatagctaa taaaagacag tgagaggtgt tatattatga ctaaaacaca
     6181 acaggaaatg atacaaaacg tattagaatt ttcaaaaaga gatagtagga taataggact
     6241 tgcaattagc ggttcttata tcacaaaatc gttagatgaa tattctgatt tggattttct
     6301 gattgtagca gatgataaat cctatgaaga agttatcgaa gagagattac ttattgtgga
     6361 acagtttgga acattagttt ctgcttttac tggcgaacac gttggagaac ctcgattgat
     6421 aatttccctc tatgatttcc ctgttcttca tgttgatttt aagtttacaa ccttagatgg
     6481 tttactagat agggttgaag attcagctat tctctatgaa gaaaacaact gcataacaga
     6541 aatttattct aaaaaagaag catacttccc aactccagac ttacagtgga ttgaagatag
     6601 attttggatt tgggttcatt acgcttgcac taagattgga cgtagagaac tatttgaaac
     6661 aattgatttt ttatcttttt taagacaatc agtacttgcc ccattaatac agcttctctt
     6721 aggtaaatta cctcgtggag ttagaaaaat tgaattggac gcaccccaat atattgaagc
     6781 attagaaaag acggttgcta accatgaata taaaagctgt gttaatgcat tgcaggctac
     6841 tatcaacctg tatcttgagt taagagagga attatcacaa agtcctattg tccgaaaggt
     6901 tgaagctgaa agggttgcat tacagtattt tcaagattta atcaaataaa cccaaagtaa
     6961 aaaaatattg aatagtaaat attcagtgtt ttttcatttt tggtcaaatg acctagatta
     7021 gttgttgtaa caattctata attattttga aagtaacagt atggaggata actatgagtg
     7081 atattttaag tagaattaca aataaaattg gggataagaa tatagttgat aagttatcag
     7141 ctctatcaaa atcagatttg aactcacttc tattagaagt gtttgataga caagcaaata
     7201 ctttaactgc aactgatatt ctaaagtcat accaactaaa tagatttact atccctagcg
     7261 gtatagatcc agaagaaatt catgctttgg aatcaaaatt attgagaaaa gcattcaata
     7321 tggatatcaa gacgattatg ctttctccct ctgccccatt aggtagctgt agcgtttttg
     7381 gctccgtaga tcaatataac gtagtaagtg ctctacgagg gacagaaaca cttgcagacc
     7441 cctcaaatat gttggcaata attattgctg ataaattaaa aagaaaagaa gaaaataata
     7501 ccatacctat ccacatggct actactgcta gggtaataag agcacaaaat tttgtaggta
     7561 aaggtttata ttcacatttt ggcttatatt gtatggtttc atctggtata gatacagggt
     7621 cttacacttg tgaaaaaatg ttgttagaaa agcacttaaa ctattataaa gatatattaa
     7681 gtgaaataga aaatgttcgt ttctctatta ttctacgcaa aagaaacgga tacaaagata
     7741 atgacggatt tttcgacaga atggttgaaa ctatcaaact tatttttcct aatatagagt
     7801 tatcaattca taatgatgat gttgataata attattataa aggtatcaat ttcaaattat
     7861 cggtcaaaca aggaaatgaa accgttgaaa tagttgacgg tggatttgtt gactggactt
     7921 atcaaatgct tggaaataaa aaagaacgct gtttgataag tggtattggc ttagaaagat
     7981 ttcttgtagc tgtttcataa aaggagaaga aaaatggaac ttatagagtg gaattatgct
     8041 tatattaccg atttagttga gtttgcgaat gataaagaaa ttgcaaagaa tcttcgtgac
     8101 aacttccccc acccttatag ggagcaaaac gctagagatt ttattagttt ttgtttggca
     8161 acttcagatg ttaaacaact tagctatgct attttttatc aagaaagggc tattggaagt
     8221 atcagcctaa catttgaaga agatacctct attaataaaa atgctgaatt aggttactgg
     8281 cttgctagga actattgagg caaagggata gcaacaaatg cagtaaaaga aatatgcaaa
     8341 attgcctttg aaaaatacaa ccttaacaaa attcatgcta atgtatattc ctacaataga
     8401 gagtcaagta aagtattgga aaaatgtggc tttaagattg aagaatactg tcacaattca
     8461 taataaagaa tagaaacatg attgattgcc atgtatatag tttaattcga ccgcaatagc
     8521 atttattaga attaacctac tttttaataa cagaataagt ttttcccctc tattaatttc
     8581 ttatgcatct ttgtattttt atgaaaagct agccaatgca tatttccata catcaatatg
     8641 gtggtggctt acaaccaata taaattaaat acgttttaaa gaatacacat ttttgcccta
     8701 taggcagagt gtgtattttt ttctcttttt tttgaaattt atcgaagatt taacgccctc
     8761 ccaccgtgat aggagtaagc aaggttattt aactccttgc gatggaaaga gggtgaaatc
     8821 ttatggttga tgaaaagaca attgaacatc aattcgacag tttctgtaaa acagttttgc
     8881 gtaactatgc tagagatatt tatgacgaaa ataaacgcag aaatgattat ttggtatctc
     8941 tcgaatcttt gtcacttgca gaattaagta aattgagtat tttagatgat tatgattcta
     9001 actacatctg tatggtttct tacgactaca acatacgaat tgaagatgta ttaatggcgc
     9061 aagcaatcgg aaaacttaca aaaagaaaac aagatataat tctactttca ttctttctca
     9121 acatgacaaa tgctgacata gcaacattga tggatttagc agaaaatacc atacattatc
     9181 acaaaacaaa tgcactaaaa gagttgaaag aactcatgga ggaacattga aatgaaacct
     9241 actaaagaag tattaccttt tacaattatt ttacttgctg tacatggcga tgtaaatgca
     9301 ataaacggaa tacttaaaca ttttgaacac tatatcattc gtctttcaca gaaaacttta
     9361 tttgataaat acggaaatcc ctatattcat gtagaagaag aaacaaagcg aatgctagga
     9421 acaaaactaa tcactgctat tttgagattt aatttgtctt aatctcgccc tctctccatg
     9481 tatcaagcta tttggtacat ggagaatcac taattatttg tctataaaag cccacaagct
     9541 attgtgattt tttataggca aatcaatgcc gactgttctt tgacaactga ataaagtaga
     9601 tagatacgtt tgtgatacag atagccaaca aatattatac gccatgacct taatcaagag
     9661 agccactata tagtgatttg tgaataacct ttggaacggt tgttttgccg tcacagtata
     9721 atgatacacc tgtatgacac ggttttgccc ataagaatgg gattggttga aataccaatg
     9781 gagcttacca aagccatcta tctacttctg aactacgaac atagaaagga gtgatacatt
     9841 ctatgaacaa tactgatgta cctatttggg aaaaatatac cttgacgatt gaagaagcgt
     9901 caaaatactt tcgtattgga gagaaaaaat tacgtaaact tgctgatgaa aaccttgatt
     9961 ctggctgggt cattatgaat ggcaatcgca ttcaaataaa gagaaaacaa tttgagaaaa
    10021 tcgttgatac acttgacgtt atctaataaa atcgagcctt atatgttata atattcatat
    10081 gacgtatcaa gctcaattcg gttattgaga ggagcttctt atcatgtcaa ctgaaaaaag
    10141 acgagataat aaagatagaa ttttaagaac tggagagagc cagagaaaag atggaagata
    10201 cgcatataag tatgtagatt catttggtaa accacaattt gtttattctt ggaaacttgt
    10261 atctactgat aaacccccaa agggaaaacg tgatgatata tcattaaggg ataaggaaaa
    10321 agcaatacaa aatgaccttg atgatagcat tgacactatt ggtaagaaaa tgacagtttg
    10381 tcagttacac gctaaaaaga atgtactaag aaagaatatc cgacttaaca ctaaaaaagg
    10441 acgccattat cttatgaaga ttctgaacaa ggagtgattc tgtgaagaga tgtattgtag
    10501 tagtggaata gtcaaaaaca taatatatat taaaggagag atttaaatat gactattcca
    10561 agttcaaata aggtatatcc aagaagtaat gattatcaaa ctgtatatct taaaaatgta
    10621 ataacaaggg aaaatataga agttggagat tacacaatat ataatgactt ttataatgac
    10681 ccaagagatt ttgagaaaaa caatgtattg tatcattacc ctataaacaa tgataaatta
    10741 ataattggta agttttgctc aatagcatgt aatgcaaaat ttctaatgac tagtggaaat
    10801 cactcaatga aatcaaaatc cacatatact tttcccatct tttatgaaga atggaaactc
    10861 gatatcaacc atataacgga cgcttgggac aataagggta acattataat tggaaatgat
    10921 gtgtggatag gttatgattc tataattatg tcaggtgtaa atattggtga tggtgcaatt
    10981 attggaacaa gagcagtagt tactaatgac gttccaccgt attctattgt tggaggagta
    11041 cctgcaaaaa ttataaaaaa gagatttaat aatgatacaa tttcaaaatt attagaaatt
    11101 aaatggtggg attggccata taaaaaaatt caatcaaaca ttaagcatat tcaatcagga
    11161 aatattgata aattagttta atattttata atttatttat attaaacttt actttaataa
    11221 tcattttata agagcttttt caaaatttgt atattatttt aatatatata aatttaatac
//
